ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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| Clone Name | basd3d10 |
|---|---|
| Clone Library Name | barley_pub |
>ASPRX_ORYSA (P42211) Aspartic proteinase precursor (EC 3.4.23.-)| Length = 496 Score = 199 bits (507), Expect = 3e-51 Identities = 102/158 (64%), Positives = 120/158 (75%) Frame = +2 Query: 86 LGVTCLWILSCALLLGGACSDGLLRINLSKKRLDKETLTAAKLARQETKLLRSDDGSRHS 265 L TCLW LSCALLL A SDG LR+NL+KKRLDKE LTAAKLA+Q +LL++ Sbjct: 8 LVTTCLWALSCALLLH-ASSDGFLRVNLNKKRLDKEDLTAAKLAQQGNRLLKT------- 59 Query: 266 LGLSGDDIVPLDNYLDTQYFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKCYFSIACYLHH 445 G S D VPL +YL+TQY+G IG+G+PPQNFTVIFDTGSSNLWVPS+KCYFSIACYLH Sbjct: 60 -GSSDSDPVPLVDYLNTQYYGVIGLGSPPQNFTVIFDTGSSNLWVPSAKCYFSIACYLHS 118 Query: 446 XXXXXXXXXXXXNGETCTISYGSGSIAGFFSEDSVLVG 559 +GETC I+YGSG+I+GFFS+D+VLVG Sbjct: 119 RYNSKKSSSYKADGETCKITYGSGAISGFFSKDNVLVG 156
>ASPR1_ORYSA (Q42456) Aspartic proteinase oryzasin-1 precursor (EC 3.4.23.-)| Length = 509 Score = 154 bits (388), Expect = 2e-37 Identities = 79/146 (54%), Positives = 98/146 (67%), Gaps = 1/146 (0%) Frame = +2 Query: 125 LLGGACSDGLLRINLSKKRLDKETLTAAKLARQETKLLRSDDGSRHSLGLSGD-DIVPLD 301 LL + ++GL+RI L K+ +D+ + AA+L+ +E G+ G G+ DIV L Sbjct: 19 LLPASAAEGLVRIALKKRPIDENSRVAARLSGEEGARRLGLRGANSLGGGGGEGDIVALK 78 Query: 302 NYLDTQYFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKCYFSIACYLHHXXXXXXXXXXXX 481 NY++ QYFGEIGVGTPPQ FTVIFDTGSSNLWVPS+KCYFSIAC+ H Sbjct: 79 NYMNAQYFGEIGVGTPPQKFTVIFDTGSSNLWVPSAKCYFSIACFFHSRYKSGQSSTYQK 138 Query: 482 NGETCTISYGSGSIAGFFSEDSVLVG 559 NG+ I YG+GSIAGFFSEDSV VG Sbjct: 139 NGKPAAIQYGTGSIAGFFSEDSVTVG 164
>ASPR_HORVU (P42210) Phytepsin precursor (EC 3.4.23.40) (Aspartic proteinase)| [Contains: Phytepsin 32 kDa subunit; Phytepsin 29 kDa subunit; Phytepsin 16 kDa subunit; Phytepsin 11 kDa subunit] Length = 508 Score = 150 bits (379), Expect = 2e-36 Identities = 82/158 (51%), Positives = 101/158 (63%), Gaps = 5/158 (3%) Frame = +2 Query: 101 LWILSCALLL-----GGACSDGLLRINLSKKRLDKETLTAAKLARQETKLLRSDDGSRHS 265 L +L+ LLL + ++GL+RI L K+ +D+ + A L+ E + L S G+ Sbjct: 8 LALLAAVLLLQTVLPAASEAEGLVRIALKKRPIDRNSRVATGLSGGEEQPLLS--GANPL 65 Query: 266 LGLSGDDIVPLDNYLDTQYFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKCYFSIACYLHH 445 DIV L NY++ QYFGEIGVGTPPQ FTVIFDTGSSNLWVPS+KCYFSIACYLH Sbjct: 66 RSEEEGDIVALKNYMNAQYFGEIGVGTPPQKFTVIFDTGSSNLWVPSAKCYFSIACYLHS 125 Query: 446 XXXXXXXXXXXXNGETCTISYGSGSIAGFFSEDSVLVG 559 NG+ I YG+GSIAG+FSEDSV VG Sbjct: 126 RYKAGASSTYKKNGKPAAIQYGTGSIAGYFSEDSVTVG 163
>ASPR_CUCPE (O04057) Aspartic proteinase precursor (EC 3.4.23.-)| Length = 513 Score = 140 bits (353), Expect = 2e-33 Identities = 73/158 (46%), Positives = 102/158 (64%), Gaps = 4/158 (2%) Frame = +2 Query: 98 CLWILSCALLLGGACSDGLLRINLSKKRLDKETLTAAKLARQETKLLRS---DDGSRHSL 268 CL++L ++ A +DGLLR+ L K +LD E AA++ ++ ++L++ + +L Sbjct: 12 CLFLLVSFNIVSSASNDGLLRVGLKKIKLDPENRLAARVESKDAEILKAAFRKYNPKGNL 71 Query: 269 GLSGD-DIVPLDNYLDTQYFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKCYFSIACYLHH 445 G S D DIV L NYLD QY+GEI +GTPPQ FTVIFDTGSSNLWV +C FS+AC+ H Sbjct: 72 GESSDTDIVALKNYLDAQYYGEIAIGTPPQKFTVIFDTGSSNLWV-LCECLFSVACHFHA 130 Query: 446 XXXXXXXXXXXXNGETCTISYGSGSIAGFFSEDSVLVG 559 NG + +I YG+G+++GFFS D+V VG Sbjct: 131 RYKSSRSSSYKKNGTSASIRYGTGAVSGFFSYDNVKVG 168
>CYPR1_CYNCA (P40782) Cyprosin precursor (EC 3.4.23.-) (Fragment)| Length = 473 Score = 133 bits (334), Expect = 4e-31 Identities = 61/112 (54%), Positives = 77/112 (68%), Gaps = 6/112 (5%) Frame = +2 Query: 242 SDDGSRHSLGLSGD------DIVPLDNYLDTQYFGEIGVGTPPQNFTVIFDTGSSNLWVP 403 +D +R G+ G+ +++ L NY+D QYFGEIG+GTPPQ FTVIFDTGSSNLWVP Sbjct: 19 NDANARRKYGVRGNFRDSDGELIALKNYMDAQYFGEIGIGTPPQKFTVIFDTGSSNLWVP 78 Query: 404 SSKCYFSIACYLHHXXXXXXXXXXXXNGETCTISYGSGSIAGFFSEDSVLVG 559 SSKCYFS+AC H NG++ I YG+GSI+GFFS+DSV +G Sbjct: 79 SSKCYFSVACLFHSKYRSTDSTTYKKNGKSAAIQYGTGSISGFFSQDSVKLG 130
>NAPSA_MOUSE (O09043) Napsin-A precursor (EC 3.4.23.-) (Kidney-derived aspartic| protease-like protein) (KDAP-1) (KAP) Length = 419 Score = 115 bits (289), Expect = 6e-26 Identities = 64/156 (41%), Positives = 87/156 (55%), Gaps = 3/156 (1%) Frame = +2 Query: 101 LWILSCALLLGGACSDG--LLRINLSKKRLDKETLTAAKLARQETKLLRSDDGSRHSLGL 274 L +L LLLG + L+R+ L + L L Q +L SR S Sbjct: 4 LLLLLLCLLLGNLEPEEAKLIRVPLQRIHLGHRILNPLNGWEQLAEL------SRTSTSG 57 Query: 275 SGDDIVPLDNYLDTQYFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKC-YFSIACYLHHXX 451 VPL +++TQYFG IG+GTPPQNFTV+FDTGSSNLWVPS++C +FS+AC+ HH Sbjct: 58 GNPSFVPLSKFMNTQYFGTIGLGTPPQNFTVVFDTGSSNLWVPSTRCHFFSLACWFHHRF 117 Query: 452 XXXXXXXXXXNGETCTISYGSGSIAGFFSEDSVLVG 559 NG I YG+G ++G S+D++ +G Sbjct: 118 NPKASSSFRPNGTKFAIQYGTGRLSGILSQDNLTIG 153
>CATD_CLUHA (Q9DEX3) Cathepsin D precursor (EC 3.4.23.5)| Length = 396 Score = 115 bits (289), Expect = 6e-26 Identities = 63/143 (44%), Positives = 85/143 (59%), Gaps = 4/143 (2%) Frame = +2 Query: 143 SDGLLRINLSKKRLDKETLTAAKLARQETKLLRSDDGSRHSLGLSGDDIVP---LDNYLD 313 SD ++RI L K R + TL+ + L ++ LL + +H+ G + L NY+D Sbjct: 16 SDAIVRIPLKKFRSIRRTLSDSGLNVEQ--LLAGTNSLQHNQGFPSSNAPTPETLKNYMD 73 Query: 314 TQYFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKCYFS-IACYLHHXXXXXXXXXXXXNGE 490 QY+GEIG+GTP Q FTV+FDTGSSNLW+PS C F+ IAC LHH NG Sbjct: 74 AQYYGEIGLGTPVQMFTVVFDTGSSNLWLPSIHCSFTDIACLLHHKYNGAKSSTYVKNGT 133 Query: 491 TCTISYGSGSIAGFFSEDSVLVG 559 I YGSGS++G+ S+DS +G Sbjct: 134 EFAIQYGSGSLSGYLSQDSCTIG 156
>NAPSA_HUMAN (O96009) Napsin-A precursor (EC 3.4.23.-) (Napsin-1) (NAPA)| (TA01/TA02) (Aspartyl protease 4) (Asp 4) (ASP4) Length = 420 Score = 115 bits (287), Expect = 1e-25 Identities = 52/91 (57%), Positives = 61/91 (67%), Gaps = 1/91 (1%) Frame = +2 Query: 290 VPLDNYLDTQYFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKC-YFSIACYLHHXXXXXXX 466 VPL NY D QYFGEIG+GTPPQNFTV FDTGSSNLWVPS +C +FS+ C+LHH Sbjct: 68 VPLSNYRDVQYFGEIGLGTPPQNFTVAFDTGSSNLWVPSRRCHFFSVPCWLHHRFDPKAS 127 Query: 467 XXXXXNGETCTISYGSGSIAGFFSEDSVLVG 559 NG I YG+G + G SED + +G Sbjct: 128 SSFQANGTKFAIQYGTGRVDGILSEDKLTIG 158
>CATD_RAT (P24268) Cathepsin D precursor (EC 3.4.23.5) [Contains: Cathepsin D| 12 kDa light chain; Cathepsin D 9 kDa light chain; Cathepsin D 34 kDa heavy chain; Cathepsin D 30 kDa heavy chain] Length = 407 Score = 111 bits (277), Expect = 2e-24 Identities = 66/152 (43%), Positives = 88/152 (57%), Gaps = 7/152 (4%) Frame = +2 Query: 122 LLLG--GACSDGLLRINLSKKRLDKETLTAAKLARQETKLLRSDDGSRHSLGLSGDDIVP 295 L+LG A S L+RI L K + T+T ++ L+ +++S+ S P Sbjct: 9 LILGLLDASSSALIRIPLRKFTSIRRTMT--EVGGSVEDLILKGPITKYSMQSSPRTKEP 66 Query: 296 ----LDNYLDTQYFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKC-YFSIACYLHHXXXXX 460 L NYLD QY+GEIG+GTPPQ FTV+FDTGSSNLWVPS C IAC++HH Sbjct: 67 VSELLKNYLDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWVHHKYNSD 126 Query: 461 XXXXXXXNGETCTISYGSGSIAGFFSEDSVLV 556 NG + I YGSGS++G+ S+D+V V Sbjct: 127 KSSTYVKNGTSFDIHYGSGSLSGYLSQDTVSV 158
>CATD_HUMAN (P07339) Cathepsin D precursor (EC 3.4.23.5) [Contains: Cathepsin D| light chain; Cathepsin D heavy chain] Length = 412 Score = 110 bits (276), Expect = 2e-24 Identities = 64/155 (41%), Positives = 88/155 (56%), Gaps = 5/155 (3%) Frame = +2 Query: 107 ILSCALLLGGACSDGLLRINLSKKRLDKETLTAAKLARQETKLLRSDDGSRHSLGLSGDD 286 +L AL L A + L+RI L K + T++ ++ L+ S++S + Sbjct: 6 LLPLALCLLAAPASALVRIPLHKFTSIRRTMS--EVGGSVEDLIAKGPVSKYSQAVPAVT 63 Query: 287 IVP----LDNYLDTQYFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKC-YFSIACYLHHXX 451 P L NY+D QY+GEIG+GTPPQ FTV+FDTGSSNLWVPS C IAC++HH Sbjct: 64 EGPIPEVLKNYMDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWIHHKY 123 Query: 452 XXXXXXXXXXNGETCTISYGSGSIAGFFSEDSVLV 556 NG + I YGSGS++G+ S+D+V V Sbjct: 124 NSDKSSTYVKNGTSFDIHYGSGSLSGYLSQDTVSV 158
>RENI_CALJA (Q9TSZ1) Renin precursor (EC 3.4.23.15) (Angiotensinogenase)| Length = 400 Score = 110 bits (276), Expect = 2e-24 Identities = 58/147 (39%), Positives = 84/147 (57%), Gaps = 1/147 (0%) Frame = +2 Query: 122 LLLGGACSDGLLRINLSKKRLDKETLTAAKLARQETKLLRSDDGSRHSLGLSGDDIVPLD 301 LLL G+C+ GL + KR+ + + + + + +E + + G ++ V L Sbjct: 14 LLLWGSCTFGLPTETTTFKRISLKRMPSIRESLKERGVDMARLGPERMALVNITSSVILT 73 Query: 302 NYLDTQYFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKC-YFSIACYLHHXXXXXXXXXXX 478 NY+DTQY+GEIG+GTPPQ F V+FDTGSSN+WVPSSKC AC H Sbjct: 74 NYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCSRLYTACVYHKLFDASDSSSYK 133 Query: 479 XNGETCTISYGSGSIAGFFSEDSVLVG 559 NG T+ Y +G+++GF S+D + VG Sbjct: 134 HNGTELTLRYSTGTVSGFLSQDVITVG 160
>CATD_CHICK (Q05744) Cathepsin D precursor (EC 3.4.23.5) [Contains: Cathepsin D| light chain; Cathepsin D heavy chain] Length = 398 Score = 110 bits (276), Expect = 2e-24 Identities = 50/89 (56%), Positives = 61/89 (68%), Gaps = 1/89 (1%) Frame = +2 Query: 296 LDNYLDTQYFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKCY-FSIACYLHHXXXXXXXXX 472 L NY+D QY+GEIG+GTPPQ FTV+FDTGSSNLWVPS C+ IAC LHH Sbjct: 70 LKNYMDAQYYGEIGIGTPPQKFTVVFDTGSSNLWVPSVHCHLLDIACLLHHKYDASKSST 129 Query: 473 XXXNGETCTISYGSGSIAGFFSEDSVLVG 559 NG I YG+GS++GF S+D+V +G Sbjct: 130 YVENGTEFAIHYGTGSLSGFLSQDTVTLG 158
>CARP_NEUCR (Q01294) Vacuolar protease A precursor (EC 3.4.23.-)| Length = 396 Score = 109 bits (273), Expect = 5e-24 Identities = 67/162 (41%), Positives = 93/162 (57%), Gaps = 11/162 (6%) Frame = +2 Query: 107 ILSCALLLGGACSDGLLRINLSKKRLDKETLTAAKLARQETKLLRSDDGSR---HSLGL- 274 +L+ A+LLG A + G+ + L K L E L + + Q L + G R H+ + Sbjct: 5 LLTAAMLLGSAQA-GVHTMKLKKVPL-AEQLESVPIDVQVQHLGQKYTGLRTESHTQAMF 62 Query: 275 -------SGDDIVPLDNYLDTQYFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKCYFSIAC 433 SG+ VP+ N+++ QYF EI +GTPPQ F V+ DTGSSNLWVPSS+C SIAC Sbjct: 63 KATDAQVSGNHPVPITNFMNAQYFSEITIGTPPQTFKVVLDTGSSNLWVPSSQC-GSIAC 121 Query: 434 YLHHXXXXXXXXXXXXNGETCTISYGSGSIAGFFSEDSVLVG 559 YLH+ NG + I YGSGS++GF S+D + +G Sbjct: 122 YLHNKYESSESSTYKKNGTSFKIEYGSGSLSGFVSQDRMTIG 163
>RENI_CANFA (Q6DYE7) Renin precursor (EC 3.4.23.15) (Angiotensinogenase)| Length = 403 Score = 109 bits (272), Expect = 6e-24 Identities = 67/154 (43%), Positives = 84/154 (54%), Gaps = 8/154 (5%) Frame = +2 Query: 122 LLLGGACSDGL-------LRINLSKKRLDKETLTAAKLARQETKLLRSDDGSRHSLGLSG 280 L+L G+C+ GL RI L K +E+L + + R S G S Sbjct: 13 LVLWGSCTFGLPADTGAFRRIFLKKMPSIRESLKERGVDVAGLGAEWNQFTKRLSSGNST 72 Query: 281 DDIVPLDNYLDTQYFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKCY-FSIACYLHHXXXX 457 +V L NYLDTQY+GEIG+GTPPQ F V+FDTGS+NLWVPS++C AC +H Sbjct: 73 SPVV-LTNYLDTQYYGEIGIGTPPQTFKVVFDTGSANLWVPSTRCSPLYTACEIHCLYDS 131 Query: 458 XXXXXXXXNGETCTISYGSGSIAGFFSEDSVLVG 559 NG T TI YGSG + GF S+D V VG Sbjct: 132 SESSSYMENGTTFTIRYGSGKVKGFLSQDMVTVG 165
>CATD_CANFA (Q4LAL9) Cathepsin D precursor (EC 3.4.23.5)| Length = 410 Score = 109 bits (272), Expect = 6e-24 Identities = 66/155 (42%), Positives = 90/155 (58%), Gaps = 5/155 (3%) Frame = +2 Query: 107 ILSCALLLGGACSDGLLRINLSKKRLDKETLTAAKLARQETKLLRSDDGSRHSLG---LS 277 +L L L A + L+RI L K + T+T +L L+ S+++ G ++ Sbjct: 6 LLLLVLGLLAAPAAALVRIPLHKFTSVRRTMT--ELGGPVEDLIAKGPISKYAQGAPAVT 63 Query: 278 GDDIVP-LDNYLDTQYFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKC-YFSIACYLHHXX 451 G I L NY+D QY+GEIG+GTPPQ FTV+FDTGSSNLWVPS C IAC++HH Sbjct: 64 GGPIPEMLRNYMDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWIHHKY 123 Query: 452 XXXXXXXXXXNGETCTISYGSGSIAGFFSEDSVLV 556 NG + I YGSGS++G+ S+D+V V Sbjct: 124 NSGKSSTYVKNGTSFDIHYGSGSLSGYLSQDTVSV 158
>CATD_MOUSE (P18242) Cathepsin D precursor (EC 3.4.23.5)| Length = 410 Score = 108 bits (270), Expect = 1e-23 Identities = 59/150 (39%), Positives = 82/150 (54%), Gaps = 5/150 (3%) Frame = +2 Query: 122 LLLGGACSDGLLRINLSKKRLDKETLTAAKLARQETKLLRSDDGSRHSLGLSGDDIVP-- 295 L+LG S I + ++ T ++ L+ +++S+ S P Sbjct: 9 LILGLLASSSFAIIRIPLRKFTSIRRTMTEVGGSVEDLILKGPITKYSMQSSPKTTEPVS 68 Query: 296 --LDNYLDTQYFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKC-YFSIACYLHHXXXXXXX 466 L NYLD QY+G+IG+GTPPQ FTV+FDTGSSNLWVPS C IAC++HH Sbjct: 69 ELLKNYLDAQYYGDIGIGTPPQCFTVVFDTGSSNLWVPSIHCKILDIACWVHHKYNSDKS 128 Query: 467 XXXXXNGETCTISYGSGSIAGFFSEDSVLV 556 NG + I YGSGS++G+ S+D+V V Sbjct: 129 STYVKNGTSFDIHYGSGSLSGYLSQDTVSV 158
>RENI_PANTR (P60016) Renin precursor (EC 3.4.23.15) (Angiotensinogenase)| Length = 406 Score = 108 bits (269), Expect = 1e-23 Identities = 60/154 (38%), Positives = 88/154 (57%), Gaps = 8/154 (5%) Frame = +2 Query: 122 LLLGGACSDGLLRINLSKKRLDKETLTAAKLARQETKLLRSDDG-------SRHSLGLSG 280 LLL G+C+ GL + KR+ + + + + + +E + + G R +LG + Sbjct: 14 LLLWGSCTFGLPTDTTTFKRIFLKRMPSIRESLKERGVDMARLGPEWSQPMKRLTLGNTT 73 Query: 281 DDIVPLDNYLDTQYFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKC-YFSIACYLHHXXXX 457 ++ L NY+DTQY+GEIG+GTPPQ F V+FDTGSSN+WVPSSKC AC H Sbjct: 74 SSVI-LTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCSRLYTACVYHKLFDA 132 Query: 458 XXXXXXXXNGETCTISYGSGSIAGFFSEDSVLVG 559 NG T+ Y +G+++GF S+D + VG Sbjct: 133 SDSSSYKHNGTELTLRYSTGTVSGFLSQDIITVG 166
>RENI_MACMU (Q6DLW5) Renin precursor (EC 3.4.23.15) (Angiotensinogenase)| Length = 406 Score = 108 bits (269), Expect = 1e-23 Identities = 60/154 (38%), Positives = 88/154 (57%), Gaps = 8/154 (5%) Frame = +2 Query: 122 LLLGGACSDGLLRINLSKKRLDKETLTAAKLARQETKLLRSDDG-------SRHSLGLSG 280 LLL G+C+ GL + KR+ + + + + + +E + + G R +LG + Sbjct: 14 LLLWGSCTFGLPTDTTTFKRIFLKRMPSIRESLKERGVDMARLGPEWSQPMKRLALGNTT 73 Query: 281 DDIVPLDNYLDTQYFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKC-YFSIACYLHHXXXX 457 ++ L NY+DTQY+GEIG+GTPPQ F V+FDTGSSN+WVPSSKC AC H Sbjct: 74 SSVI-LTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCSRLYTACVYHKLFDA 132 Query: 458 XXXXXXXXNGETCTISYGSGSIAGFFSEDSVLVG 559 NG T+ Y +G+++GF S+D + VG Sbjct: 133 SDSSSYKHNGTELTLRYSTGTVSGFLSQDIITVG 166
>RENI_MACFA (Q6DLS0) Renin precursor (EC 3.4.23.15) (Angiotensinogenase)| Length = 406 Score = 108 bits (269), Expect = 1e-23 Identities = 60/154 (38%), Positives = 88/154 (57%), Gaps = 8/154 (5%) Frame = +2 Query: 122 LLLGGACSDGLLRINLSKKRLDKETLTAAKLARQETKLLRSDDG-------SRHSLGLSG 280 LLL G+C+ GL + KR+ + + + + + +E + + G R +LG + Sbjct: 14 LLLWGSCTFGLPTDTTTFKRIFLKRMPSIRESLKERGVDMARLGPEWSQPMKRLALGNTT 73 Query: 281 DDIVPLDNYLDTQYFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKC-YFSIACYLHHXXXX 457 ++ L NY+DTQY+GEIG+GTPPQ F V+FDTGSSN+WVPSSKC AC H Sbjct: 74 SSVI-LTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCSRLYTACVYHKLFDA 132 Query: 458 XXXXXXXXNGETCTISYGSGSIAGFFSEDSVLVG 559 NG T+ Y +G+++GF S+D + VG Sbjct: 133 SDSSSYKHNGTELTLRYSTGTVSGFLSQDIITVG 166
>RENI_HUMAN (P00797) Renin precursor (EC 3.4.23.15) (Angiotensinogenase)| Length = 406 Score = 108 bits (269), Expect = 1e-23 Identities = 60/154 (38%), Positives = 88/154 (57%), Gaps = 8/154 (5%) Frame = +2 Query: 122 LLLGGACSDGLLRINLSKKRLDKETLTAAKLARQETKLLRSDDG-------SRHSLGLSG 280 LLL G+C+ GL + KR+ + + + + + +E + + G R +LG + Sbjct: 14 LLLWGSCTFGLPTDTTTFKRIFLKRMPSIRESLKERGVDMARLGPEWSQPMKRLTLGNTT 73 Query: 281 DDIVPLDNYLDTQYFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKC-YFSIACYLHHXXXX 457 ++ L NY+DTQY+GEIG+GTPPQ F V+FDTGSSN+WVPSSKC AC H Sbjct: 74 SSVI-LTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCSRLYTACVYHKLFDA 132 Query: 458 XXXXXXXXNGETCTISYGSGSIAGFFSEDSVLVG 559 NG T+ Y +G+++GF S+D + VG Sbjct: 133 SDSSSYKHNGTELTLRYSTGTVSGFLSQDIITVG 166
>RENI1_MOUSE (P06281) Renin-1 precursor (EC 3.4.23.15) (Angiotensinogenase)| (Kidney renin) Length = 402 Score = 108 bits (269), Expect = 1e-23 Identities = 52/91 (57%), Positives = 61/91 (67%), Gaps = 1/91 (1%) Frame = +2 Query: 290 VPLDNYLDTQYFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKC-YFSIACYLHHXXXXXXX 466 V L NYL+TQY+GEIG+GTPPQ F VIFDTGS+NLWVPS+KC +AC +H Sbjct: 74 VVLTNYLNTQYYGEIGIGTPPQTFKVIFDTGSANLWVPSTKCSRLYLACGIHSLYESSDS 133 Query: 467 XXXXXNGETCTISYGSGSIAGFFSEDSVLVG 559 NG TI YGSG + GF S+DSV VG Sbjct: 134 SSYMENGSDFTIHYGSGRVKGFLSQDSVTVG 164
>RENI2_MOUSE (P00796) Renin-2 precursor (EC 3.4.23.15) (Angiotensinogenase)| (Submandibular gland renin) [Contains: Renin-2 heavy chain; Renin-2 light chain] Length = 401 Score = 107 bits (267), Expect = 2e-23 Identities = 51/91 (56%), Positives = 62/91 (68%), Gaps = 1/91 (1%) Frame = +2 Query: 290 VPLDNYLDTQYFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKC-YFSIACYLHHXXXXXXX 466 V L NYL++QY+GEIG+GTPPQ F VIFDTGS+NLWVPS+KC +AC +H Sbjct: 73 VVLTNYLNSQYYGEIGIGTPPQTFKVIFDTGSANLWVPSTKCSRLYLACGIHSLYESSDS 132 Query: 467 XXXXXNGETCTISYGSGSIAGFFSEDSVLVG 559 NG+ TI YGSG + GF S+DSV VG Sbjct: 133 SSYMENGDDFTIHYGSGRVKGFLSQDSVTVG 163
>CATD_SHEEP (Q9MZS8) Cathepsin D precursor (EC 3.4.23.5) (Fragment)| Length = 365 Score = 107 bits (267), Expect = 2e-23 Identities = 49/88 (55%), Positives = 61/88 (69%), Gaps = 1/88 (1%) Frame = +2 Query: 296 LDNYLDTQYFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKC-YFSIACYLHHXXXXXXXXX 472 L NY+D QY+GEIG+GTPPQ FTV+FDTGS+NLWVPS C IAC++HH Sbjct: 46 LTNYMDAQYYGEIGIGTPPQCFTVVFDTGSANLWVPSIHCKLLDIACWVHHKYNSDKSST 105 Query: 473 XXXNGETCTISYGSGSIAGFFSEDSVLV 556 NG T I YGSGS++G+ S+D+V V Sbjct: 106 YVKNGTTFDIHYGSGSLSGYLSQDTVSV 133
>RENI_SHEEP (P52115) Renin precursor (EC 3.4.23.15) (Angiotensinogenase)| Length = 400 Score = 106 bits (264), Expect = 5e-23 Identities = 52/91 (57%), Positives = 59/91 (64%), Gaps = 1/91 (1%) Frame = +2 Query: 290 VPLDNYLDTQYFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKCY-FSIACYLHHXXXXXXX 466 V L NYLDTQY+GEIG+GTPPQ F VIFDTGS+NLWVPS+KC AC +H Sbjct: 70 VVLTNYLDTQYYGEIGIGTPPQTFKVIFDTGSANLWVPSTKCSPLYTACEIHSLYDSLES 129 Query: 467 XXXXXNGETCTISYGSGSIAGFFSEDSVLVG 559 NG TI YGSG + GF S+D V VG Sbjct: 130 SSYVENGTEFTIYYGSGKVKGFLSQDLVTVG 160
>PEPA_PIG (P00791) Pepsin A precursor (EC 3.4.23.1)| Length = 386 Score = 105 bits (261), Expect = 1e-22 Identities = 60/155 (38%), Positives = 90/155 (58%), Gaps = 3/155 (1%) Frame = +2 Query: 104 WILSCALLLGGACSDGLLRINLSKKRLDKETLTAAKLARQETKLLRSDDGSRH---SLGL 274 W+L +L++ C L+++ L +K+ ++ L + K + + S++ + L Sbjct: 3 WLLLLSLVVLSEC---LVKVPLVRKKSLRQNLIKNGKLKDFLKTHKHNPASKYFPEAAAL 59 Query: 275 SGDDIVPLDNYLDTQYFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKCYFSIACYLHHXXX 454 GD+ PL+NYLDT+YFG IG+GTP Q+FTVIFDTGSSNLWVPS C S+AC H+ Sbjct: 60 IGDE--PLENYLDTEYFGTIGIGTPAQDFTVIFDTGSSNLWVPSVYC-SSLACSDHNQFN 116 Query: 455 XXXXXXXXXNGETCTISYGSGSIAGFFSEDSVLVG 559 + +I+YG+GS+ G D+V VG Sbjct: 117 PDDSSTFEATSQELSITYGTGSMTGILGYDTVQVG 151
>PEPA4_MACFU (P27678) Pepsin A-4 precursor (EC 3.4.23.1) (Pepsin I/II)| Length = 388 Score = 105 bits (261), Expect = 1e-22 Identities = 58/155 (37%), Positives = 85/155 (54%), Gaps = 3/155 (1%) Frame = +2 Query: 104 WILSCALLLGGACSDGLLRINLSKKRLDKETLTAAKLARQETKLLRSDDGSRHSLGLSGD 283 W+L L+ C + ++ L +K+ + L+ L + K + S++ Sbjct: 3 WLLLLGLVALSECI--IYKVPLVRKKSLRRNLSEHGLLKDFLKKHNLNPASKYFPQAEAP 60 Query: 284 DIV---PLDNYLDTQYFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKCYFSIACYLHHXXX 454 ++ PL+NYLD +YFG IG+GTP QNFTV+FDTGSSNLWVPS CY S+AC H+ Sbjct: 61 TLIDEQPLENYLDVEYFGTIGIGTPAQNFTVVFDTGSSNLWVPSVYCY-SLACMDHNLFN 119 Query: 455 XXXXXXXXXNGETCTISYGSGSIAGFFSEDSVLVG 559 +T +I+YG+GS+ G D+V VG Sbjct: 120 PQDSSTYRATSKTVSITYGTGSMTGILGYDTVKVG 154
>ASPP_AEDAE (Q03168) Lysosomal aspartic protease precursor (EC 3.4.23.-)| Length = 387 Score = 104 bits (260), Expect = 1e-22 Identities = 50/97 (51%), Positives = 64/97 (65%), Gaps = 1/97 (1%) Frame = +2 Query: 272 LSGDDIVPLDNYLDTQYFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKCYF-SIACYLHHX 448 +SG PL NYLD QY+G I +GTPPQ+F V+FDTGSSNLWVPS +C F +IAC +H+ Sbjct: 52 VSGPVPEPLSNYLDAQYYGAITIGTPPQSFKVVFDTGSSNLWVPSKECSFTNIACLMHNK 111 Query: 449 XXXXXXXXXXXNGETCTISYGSGSIAGFFSEDSVLVG 559 NG I YGSGS++G+ S D+V +G Sbjct: 112 YNAKKSSTFEKNGTAFHIQYGSGSLSGYLSTDTVGLG 148
>CATD_PIG (P00795) Cathepsin D precursor (EC 3.4.23.5) [Contains: Cathepsin D| light chain; Cathepsin D heavy chain] Length = 345 Score = 104 bits (260), Expect = 1e-22 Identities = 50/89 (56%), Positives = 61/89 (68%), Gaps = 2/89 (2%) Frame = +2 Query: 296 LDNYLDTQYFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKC-YFSIACYLHHXXXXXXXXX 472 L NY+D QY+GEIG+GTPPQ FTV+FDTGSSNLWVPS C IAC++HH Sbjct: 7 LKNYMDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWIHHKYNSGKSST 66 Query: 473 XXXNGETCTISYGSGSIAGFF-SEDSVLV 556 NG T I YGSGS++G+ S+D+V V Sbjct: 67 YVKNGTTFAIHYGSGSLSGYLSSQDTVSV 95
>RENI_RAT (P08424) Renin precursor (EC 3.4.23.15) (Angiotensinogenase)| Length = 402 Score = 104 bits (259), Expect = 2e-22 Identities = 51/91 (56%), Positives = 59/91 (64%), Gaps = 1/91 (1%) Frame = +2 Query: 290 VPLDNYLDTQYFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKC-YFSIACYLHHXXXXXXX 466 V L NYLDTQY+GEIG+GTP Q F VIFDTGS+NLWVPS+KC AC +H+ Sbjct: 74 VVLTNYLDTQYYGEIGIGTPSQTFKVIFDTGSANLWVPSTKCGPLYTACEIHNLYDSSES 133 Query: 467 XXXXXNGETCTISYGSGSIAGFFSEDSVLVG 559 NG TI YGSG + GF S+D V VG Sbjct: 134 SSYMENGTEFTIHYGSGKVKGFLSQDVVTVG 164
>CATD_BOVIN (P80209) Cathepsin D precursor (EC 3.4.23.5)| Length = 390 Score = 103 bits (257), Expect = 3e-22 Identities = 48/88 (54%), Positives = 59/88 (67%), Gaps = 1/88 (1%) Frame = +2 Query: 296 LDNYLDTQYFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKC-YFSIACYLHHXXXXXXXXX 472 L NY+D QY+GEIG+GTPPQ FTV+FDTGS+NLWVPS C IAC+ H Sbjct: 51 LKNYMDAQYYGEIGIGTPPQCFTVVFDTGSANLWVPSIHCKLLDIACWTHRKYNSDKSST 110 Query: 473 XXXNGETCTISYGSGSIAGFFSEDSVLV 556 NG T I YGSGS++G+ S+D+V V Sbjct: 111 YVKNGTTFDIHYGSGSLSGYLSQDTVSV 138
>PEPC_RAT (P04073) Gastricsin precursor (EC 3.4.23.3) (Pepsinogen C)| Length = 392 Score = 103 bits (256), Expect = 4e-22 Identities = 59/148 (39%), Positives = 79/148 (53%), Gaps = 2/148 (1%) Frame = +2 Query: 119 ALLLGGACSDGLLRINLSKKRLDKETLTAAKLARQETKLLRSDDGSRHSLGLSGDDIVPL 298 ALL LLR+ L K + +ET+ + + K + D G ++ G GD V Sbjct: 7 ALLCLPLLEASLLRVPLRKMKSIRETMKEQGVLKDFLKTHKYDPGQKYHFGNFGDYSVLY 66 Query: 299 DN--YLDTQYFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKCYFSIACYLHHXXXXXXXXX 472 + Y+D YFGEI +GTPPQNF V+FDTGSSNLWV S C S AC H Sbjct: 67 EPMAYMDASYFGEISIGTPPQNFLVLFDTGSSNLWVSSVYCQ-SEACTTHARFNPSKSST 125 Query: 473 XXXNGETCTISYGSGSIAGFFSEDSVLV 556 G+T ++ YG+GS+ GFF D++ V Sbjct: 126 YYTEGQTFSLQYGTGSLTGFFGYDTLTV 153
>PEPA3_RABIT (P27822) Pepsin-3 precursor (EC 3.4.23.1) (Pepsin III) (Pepsin A)| Length = 387 Score = 103 bits (256), Expect = 4e-22 Identities = 62/155 (40%), Positives = 88/155 (56%), Gaps = 3/155 (1%) Frame = +2 Query: 104 WILSCALLLGGACSDGLLRINLSKKRLDKETLTAAKLARQETKLLRSDDGSRHSLGLSGD 283 W+L LL C + ++ L +K+ ++ L L + K + +++ L + Sbjct: 3 WLLLLGLLALSECI--IHKVPLVRKKSLRKNLIEKGLLKDYLKTHTPNLATKY-LPKAAF 59 Query: 284 DIVP---LDNYLDTQYFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKCYFSIACYLHHXXX 454 D VP L+NYLDT+YFG IG+GTP Q+FTVIFDTGSSNLWVPS C S AC +H+ Sbjct: 60 DSVPTETLENYLDTEYFGTIGIGTPAQDFTVIFDTGSSNLWVPSVYC-SSAACSVHNQFN 118 Query: 455 XXXXXXXXXNGETCTISYGSGSIAGFFSEDSVLVG 559 E+ +I+YG+GS+ GF D+V VG Sbjct: 119 PEDSSTFQATSESLSITYGTGSMTGFLGYDTVKVG 153
>PEPC_CALJA (Q9N2D3) Gastricsin precursor (EC 3.4.23.3) (Pepsinogen C)| Length = 388 Score = 102 bits (254), Expect = 7e-22 Identities = 54/135 (40%), Positives = 76/135 (56%) Frame = +2 Query: 152 LLRINLSKKRLDKETLTAAKLARQETKLLRSDDGSRHSLGLSGDDIVPLDNYLDTQYFGE 331 ++++ L K + +ET+ L + K + D ++ + P+D Y+D YFGE Sbjct: 18 VVKVPLKKFKSIRETMKEKGLLWEFLKTHKHDPARKYRVSDLSVSYEPMD-YMDAAYFGE 76 Query: 332 IGVGTPPQNFTVIFDTGSSNLWVPSSKCYFSIACYLHHXXXXXXXXXXXXNGETCTISYG 511 I +GTPPQNF V+FDTGSSNLWVPS C S AC H NG+T ++ YG Sbjct: 77 ISIGTPPQNFLVLFDTGSSNLWVPSVYCQ-SQACTSHSRFNPSASSTYSSNGQTFSLQYG 135 Query: 512 SGSIAGFFSEDSVLV 556 SGS+ GFF D++ V Sbjct: 136 SGSLTGFFGYDTLTV 150
>CATEA_XENLA (Q805F3) Cathepsin E-A precursor (EC 3.4.23.34)| Length = 397 Score = 102 bits (254), Expect = 7e-22 Identities = 63/148 (42%), Positives = 84/148 (56%), Gaps = 3/148 (2%) Frame = +2 Query: 122 LLLGGACSDGLLRINLSKKRLDKETLTA-AKLARQETKLLRSDDGSRHSLGLSGDDIV-- 292 LLL GL+R+ L +++ ++TL KL+ T+ + D +++ S D Sbjct: 7 LLLFATLVYGLIRVPLKRQKSIRKTLKEKGKLSHIWTQ--QGIDMVQYTDSCSNDQAPSE 64 Query: 293 PLDNYLDTQYFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKCYFSIACYLHHXXXXXXXXX 472 PL NY+D +YFGEI VGTPPQNFTVIFDTGSSNLWVPS C S AC H Sbjct: 65 PLINYMDVEYFGEISVGTPPQNFTVIFDTGSSNLWVPSVYC-ISQACAQHDRFQPQLSST 123 Query: 473 XXXNGETCTISYGSGSIAGFFSEDSVLV 556 NG ++ YG+GS++G D+V V Sbjct: 124 YESNGNNFSLQYGTGSLSGVIGIDAVTV 151
>CARP_YEAST (P07267) Saccharopepsin precursor (EC 3.4.23.25) (Aspartate| protease) (Proteinase A) (Proteinase YSCA) Length = 405 Score = 102 bits (254), Expect = 7e-22 Identities = 54/126 (42%), Positives = 72/126 (57%) Frame = +2 Query: 182 LDKETLTAAKLARQETKLLRSDDGSRHSLGLSGDDIVPLDNYLDTQYFGEIGVGTPPQNF 361 L ++ LT + A E R H G VPL NYL+ QY+ +I +GTPPQNF Sbjct: 50 LGQKYLTQFEKANPEVVFSRE-----HPFFTEGGHDVPLTNYLNAQYYTDITLGTPPQNF 104 Query: 362 TVIFDTGSSNLWVPSSKCYFSIACYLHHXXXXXXXXXXXXNGETCTISYGSGSIAGFFSE 541 VI DTGSSNLWVPS++C S+AC+LH NG I YG+GS+ G+ S+ Sbjct: 105 KVILDTGSSNLWVPSNEC-GSLACFLHSKYDHEASSSYKANGTEFAIQYGTGSLEGYISQ 163 Query: 542 DSVLVG 559 D++ +G Sbjct: 164 DTLSIG 169
>PEPA1_RABIT (P28712) Pepsin II-1 precursor (EC 3.4.23.1) (Pepsin A)| Length = 387 Score = 102 bits (253), Expect = 1e-21 Identities = 48/88 (54%), Positives = 59/88 (67%) Frame = +2 Query: 296 LDNYLDTQYFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKCYFSIACYLHHXXXXXXXXXX 475 L+NYLD +YFG I +GTPPQ FTVIFDTGSSNLWVPS+ C S+AC+LH Sbjct: 67 LENYLDAEYFGTISIGTPPQEFTVIFDTGSSNLWVPSTYC-SSLACFLHKRFNPDDSSTF 125 Query: 476 XXNGETCTISYGSGSIAGFFSEDSVLVG 559 ET +I+YG+GS+ G D+V VG Sbjct: 126 QATSETLSITYGTGSMTGILGYDTVKVG 153
>PEPC_MOUSE (Q9D7R7) Gastricsin precursor (EC 3.4.23.3) (Pepsinogen C)| Length = 392 Score = 101 bits (251), Expect = 2e-21 Identities = 59/151 (39%), Positives = 81/151 (53%), Gaps = 2/151 (1%) Frame = +2 Query: 110 LSCALLLGGACSDGLLRINLSKKRLDKETLTAAKLARQETKLLRSDDGSRHSLGLSGDDI 289 L C LL A L+R+ L K + +ET+ + + K + D G ++ G GD Sbjct: 8 LLCLPLLEAA----LIRVPLKKMKSIRETMKEQGVLKDFLKNHKYDPGQKYHFGKFGDYS 63 Query: 290 VPLDN--YLDTQYFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKCYFSIACYLHHXXXXXX 463 V + Y+D Y+GEI +GTPPQNF V+FDTGSSNLWV S C S AC H Sbjct: 64 VLYEPMAYMDASYYGEISIGTPPQNFLVLFDTGSSNLWVSSVYCQ-SEACTTHTRYNPSK 122 Query: 464 XXXXXXNGETCTISYGSGSIAGFFSEDSVLV 556 G+T ++ YG+GS+ GFF D++ V Sbjct: 123 SSTYYTQGQTFSLQYGTGSLTGFFGYDTLRV 153
>PEPA_HUMAN (P00790) Pepsin A precursor (EC 3.4.23.1)| Length = 388 Score = 101 bits (251), Expect = 2e-21 Identities = 58/155 (37%), Positives = 84/155 (54%), Gaps = 3/155 (1%) Frame = +2 Query: 104 WILSCALLLGGACSDGLLRINLSKKRLDKETLTAAKLARQETKLLRSDDGSRHSLGLSGD 283 W+L L+ C + ++ L +K+ + TL+ L + K + ++ Sbjct: 3 WLLLLGLVALSECI--MYKVPLIRKKSLRRTLSERGLLKDFLKKHNLNPARKYFPQWEAP 60 Query: 284 DIV---PLDNYLDTQYFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKCYFSIACYLHHXXX 454 +V PL+NYLD +YFG IG+GTP Q+FTV+FDTGSSNLWVPS C S+AC H+ Sbjct: 61 TLVDEQPLENYLDMEYFGTIGIGTPAQDFTVVFDTGSSNLWVPSVYC-SSLACTNHNRFN 119 Query: 455 XXXXXXXXXNGETCTISYGSGSIAGFFSEDSVLVG 559 ET +I+YG+GS+ G D+V VG Sbjct: 120 PEDSSTYQSTSETVSITYGTGSMTGILGYDTVQVG 154
>CATEB_XENLA (Q805F2) Cathepsin E-B precursor (EC 3.4.23.34)| Length = 397 Score = 101 bits (251), Expect = 2e-21 Identities = 60/139 (43%), Positives = 79/139 (56%), Gaps = 3/139 (2%) Frame = +2 Query: 149 GLLRINLSK-KRLDKETLTAAKLARQETKLLRSDDGSRHSLGLSGDDIV--PLDNYLDTQ 319 GL+R+ L + K + K KL+ T+ + D +++ + D PL NY+D Q Sbjct: 16 GLIRVPLKRQKSIRKTPKEKGKLSHVWTQ--QGIDMVQYTDSCNNDQAPSEPLINYMDVQ 73 Query: 320 YFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKCYFSIACYLHHXXXXXXXXXXXXNGETCT 499 YFGEI +GTPPQNFTVIFDTGSSNLWVPS C S AC H+ NG + Sbjct: 74 YFGEISIGTPPQNFTVIFDTGSSNLWVPSVYC-ISPACAQHNRFQPQLSSTYESNGNNFS 132 Query: 500 ISYGSGSIAGFFSEDSVLV 556 + YG+GS++G DSV V Sbjct: 133 LQYGTGSLSGVIGIDSVTV 151
>PEPC_HUMAN (P20142) Gastricsin precursor (EC 3.4.23.3) (Pepsinogen C)| Length = 388 Score = 100 bits (250), Expect = 2e-21 Identities = 58/150 (38%), Positives = 81/150 (54%) Frame = +2 Query: 107 ILSCALLLGGACSDGLLRINLSKKRLDKETLTAAKLARQETKLLRSDDGSRHSLGLSGDD 286 +L C LL A ++++ L K + +ET+ L + + + D ++ G Sbjct: 7 VLVCLQLLEAA----VVKVPLKKFKSIRETMKEKGLLGEFLRTHKYDPAWKYRFGDLSVT 62 Query: 287 IVPLDNYLDTQYFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKCYFSIACYLHHXXXXXXX 466 P+ Y+D YFGEI +GTPPQNF V+FDTGSSNLWVPS C S AC H Sbjct: 63 YEPMA-YMDAAYFGEISIGTPPQNFLVLFDTGSSNLWVPSVYCQ-SQACTSHSRFNPSES 120 Query: 467 XXXXXNGETCTISYGSGSIAGFFSEDSVLV 556 NG+T ++ YGSGS+ GFF D++ V Sbjct: 121 STYSTNGQTFSLQYGSGSLTGFFGYDTLTV 150
>PEPA4_RABIT (P28713) Pepsin II-4 precursor (EC 3.4.23.1) (Pepsin A)| Length = 387 Score = 100 bits (248), Expect = 4e-21 Identities = 48/88 (54%), Positives = 59/88 (67%) Frame = +2 Query: 296 LDNYLDTQYFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKCYFSIACYLHHXXXXXXXXXX 475 L+NYLD +YFG I +GTPPQ+FTVIFDTGSSNLWVPS+ C S+AC LH Sbjct: 67 LENYLDAEYFGTISIGTPPQDFTVIFDTGSSNLWVPSTYC-SSLACALHKRFNPEDSSTY 125 Query: 476 XXNGETCTISYGSGSIAGFFSEDSVLVG 559 ET +I+YG+GS+ G D+V VG Sbjct: 126 QGTSETLSITYGTGSMTGILGYDTVKVG 153
>PEPA_CALJA (Q9N2D4) Pepsin A precursor (EC 3.4.23.1)| Length = 387 Score = 99.8 bits (247), Expect = 5e-21 Identities = 61/155 (39%), Positives = 85/155 (54%), Gaps = 3/155 (1%) Frame = +2 Query: 104 WILSCALLLGGACSDGLLRINLSKKRLDKETLTAAKLARQETKLLRSDDGSRHSLGLSGD 283 W+L +L+ A S+ L +++L KK+ ++ L L + K D S++ Sbjct: 3 WLLLLSLV---ALSECLYKVSLIKKKSLRKNLIEHGLLKDFLKNNTLDPASKYFPQGEAA 59 Query: 284 DIV---PLDNYLDTQYFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKCYFSIACYLHHXXX 454 ++ PL NYLD +YFG IG+GTP Q FTVIFDTGSSNLWVPS C S AC H+ Sbjct: 60 TMIANQPLVNYLDMEYFGTIGIGTPAQEFTVIFDTGSSNLWVPSIYC-SSPACTNHNRFN 118 Query: 455 XXXXXXXXXNGETCTISYGSGSIAGFFSEDSVLVG 559 +T +I+YG+GS+ G D+V VG Sbjct: 119 PQESSTYQATSQTLSIAYGTGSMTGILGYDTVQVG 153
>PEPA_MACMU (P11489) Pepsin A precursor (EC 3.4.23.1)| Length = 388 Score = 99.4 bits (246), Expect = 6e-21 Identities = 57/155 (36%), Positives = 83/155 (53%), Gaps = 3/155 (1%) Frame = +2 Query: 104 WILSCALLLGGACSDGLLRINLSKKRLDKETLTAAKLARQETKLLRSDDGSRHSLGLSGD 283 W+L L+ C + ++ L +K+ + L+ L + K + S++ Sbjct: 3 WLLLLGLVALSECI--IYKVPLVRKKSLRRNLSEHGLLKDFLKKHNRNPASKYFPQTEAP 60 Query: 284 DIV---PLDNYLDTQYFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKCYFSIACYLHHXXX 454 ++ PL+NYLD +YFG IG+GTP Q+FTVIFDTGSSNLWVPS C S+AC H+ Sbjct: 61 TLIDEQPLENYLDVEYFGTIGIGTPAQDFTVIFDTGSSNLWVPSVYC-SSLACTNHNLFN 119 Query: 455 XXXXXXXXXNGETCTISYGSGSIAGFFSEDSVLVG 559 T +I+YG+GS+ G D+V VG Sbjct: 120 PQDSSTYQSTSGTLSITYGTGSMTGILGYDTVQVG 154
>PEPA2_RABIT (P27821) Pepsin II-2/3 precursor (EC 3.4.23.1) (Pepsin A)| Length = 387 Score = 99.4 bits (246), Expect = 6e-21 Identities = 47/88 (53%), Positives = 59/88 (67%) Frame = +2 Query: 296 LDNYLDTQYFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKCYFSIACYLHHXXXXXXXXXX 475 ++NYLD +YFG I +GTPPQ+FTVIFDTGSSNLWVPS+ C S+AC LH Sbjct: 67 MENYLDAEYFGTISIGTPPQDFTVIFDTGSSNLWVPSTYC-SSLACALHKRFNPEDSSTY 125 Query: 476 XXNGETCTISYGSGSIAGFFSEDSVLVG 559 ET +I+YG+GS+ G D+V VG Sbjct: 126 QGTSETLSITYGTGSMTGILGYDTVKVG 153
>PEPA1_MACFU (P03954) Pepsin A-1 precursor (EC 3.4.23.1) (Pepsin III-3)| Length = 388 Score = 99.0 bits (245), Expect = 8e-21 Identities = 57/155 (36%), Positives = 83/155 (53%), Gaps = 3/155 (1%) Frame = +2 Query: 104 WILSCALLLGGACSDGLLRINLSKKRLDKETLTAAKLARQETKLLRSDDGSRHSLGLSGD 283 W+L L+ C + ++ L +K+ + L+ L + K + S++ Sbjct: 3 WLLLLGLVALSECI--IYKVPLVRKKSLRRNLSEHGLLKDFLKKHNLNPASKYFPQAEAP 60 Query: 284 DIV---PLDNYLDTQYFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKCYFSIACYLHHXXX 454 ++ PL+NYLD +YFG IG+GTP Q+FTVIFDTGSSNLWVPS C S+AC H+ Sbjct: 61 TLIDEQPLENYLDVEYFGTIGIGTPAQDFTVIFDTGSSNLWVPSVYC-SSLACTNHNLFN 119 Query: 455 XXXXXXXXXNGETCTISYGSGSIAGFFSEDSVLVG 559 T +I+YG+GS+ G D+V VG Sbjct: 120 PQDSSTYQSTSGTLSITYGTGSMTGILGYDTVQVG 154
>PEPC_MACFU (P03955) Gastricsin precursor (EC 3.4.23.3) (Pepsinogen C)| (Fragment) Length = 377 Score = 99.0 bits (245), Expect = 8e-21 Identities = 53/135 (39%), Positives = 75/135 (55%) Frame = +2 Query: 152 LLRINLSKKRLDKETLTAAKLARQETKLLRSDDGSRHSLGLSGDDIVPLDNYLDTQYFGE 331 ++++ L K + +ET+ L + + + D ++ G P+ Y+D YFGE Sbjct: 7 VVKVPLKKFKSIRETMKEKGLLGEFLRTHKYDPAWKYHFGDLSVSYEPMA-YMDAAYFGE 65 Query: 332 IGVGTPPQNFTVIFDTGSSNLWVPSSKCYFSIACYLHHXXXXXXXXXXXXNGETCTISYG 511 I +GTPPQNF V+FDTGSSNLWVPS C S AC H NG+T ++ YG Sbjct: 66 ISIGTPPQNFLVLFDTGSSNLWVPSVYCQ-SQACTSHSRFNPSESSTYSTNGQTFSLQYG 124 Query: 512 SGSIAGFFSEDSVLV 556 SGS+ GFF D++ V Sbjct: 125 SGSLTGFFGYDTLTV 139
>PEPA_BOVIN (P00792) Pepsin A precursor (EC 3.4.23.1)| Length = 372 Score = 98.6 bits (244), Expect = 1e-20 Identities = 49/89 (55%), Positives = 58/89 (65%) Frame = +2 Query: 293 PLDNYLDTQYFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKCYFSIACYLHHXXXXXXXXX 472 PL NYLDT+YFG IG+GTP Q+FTVIFDTGSSNLWVPS C S AC H+ Sbjct: 51 PLQNYLDTEYFGTIGIGTPAQDFTVIFDTGSSNLWVPSIYC-SSEACTNHNRFNPQDSST 109 Query: 473 XXXNGETCTISYGSGSIAGFFSEDSVLVG 559 ET +I+YG+GS+ G D+V VG Sbjct: 110 YEATSETLSITYGTGSMTGILGYDTVQVG 138
>PEPC_SORUN (Q9GMY4) Gastricsin precursor (EC 3.4.23.3) (Pepsinogen C)| Length = 389 Score = 98.2 bits (243), Expect = 1e-20 Identities = 59/147 (40%), Positives = 78/147 (53%) Frame = +2 Query: 110 LSCALLLGGACSDGLLRINLSKKRLDKETLTAAKLARQETKLLRSDDGSRHSLGLSGDDI 289 L C LL A ++++ L K + +ETL L + + D ++ G Sbjct: 8 LVCLQLLEAA----VVKVPLKKFKSIRETLREQGLLGEFLRTHPYDPAQKYHFGDFSVAY 63 Query: 290 VPLDNYLDTQYFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKCYFSIACYLHHXXXXXXXX 469 P+ YLD YFGEI +GTPPQNF V+FDTGSSNLWVPS C S AC H Sbjct: 64 EPMA-YLDAAYFGEISIGTPPQNFLVLFDTGSSNLWVPSVYCQ-SQACTGHARFNPSKSS 121 Query: 470 XXXXNGETCTISYGSGSIAGFFSEDSV 550 NG+T ++ YGSGS+ GFF D++ Sbjct: 122 TYSTNGQTFSLQYGSGSLTGFFGYDTM 148
>PEPA2_MACFU (P27677) Pepsin A-2/A-3 precursor (EC 3.4.23.1) (Pepsin| III-2/III-1) Length = 388 Score = 97.8 bits (242), Expect = 2e-20 Identities = 57/155 (36%), Positives = 83/155 (53%), Gaps = 3/155 (1%) Frame = +2 Query: 104 WILSCALLLGGACSDGLLRINLSKKRLDKETLTAAKLARQETKLLRSDDGSRHSLGLSGD 283 W+L L+ C + ++ L +K+ + L+ L + K + S++ Sbjct: 3 WLLLLGLVALSECI--IHKVPLVRKKSLRRNLSEHGLLKDFLKKHNFNPASKYFPQAEAP 60 Query: 284 DIV---PLDNYLDTQYFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKCYFSIACYLHHXXX 454 ++ PL+NYLD +YFG IG+GTP Q+FTVIFDTGSSNLWVPS C S+AC H+ Sbjct: 61 TLIDEQPLENYLDMEYFGTIGIGTPAQDFTVIFDTGSSNLWVPSVYC-SSLACTNHNRFN 119 Query: 455 XXXXXXXXXNGETCTISYGSGSIAGFFSEDSVLVG 559 T +I+YG+GS+ G D+V VG Sbjct: 120 PQDSSTYQSTSGTVSITYGTGSMTGILGYDTVQVG 154
>PEPC_SUNMU (P81498) Gastricsin precursor (EC 3.4.23.3) (Pepsinogen C-1)| Length = 389 Score = 97.4 bits (241), Expect = 2e-20 Identities = 54/133 (40%), Positives = 70/133 (52%) Frame = +2 Query: 158 RINLSKKRLDKETLTAAKLARQETKLLRSDDGSRHSLGLSGDDIVPLDNYLDTQYFGEIG 337 ++ L K + +E L L K D ++ G P+ Y+D YFGEI Sbjct: 20 KVTLKKFKSIRENLREQGLLEDFLKTNHYDPAQKYHFGDFSVAYEPMA-YMDASYFGEIS 78 Query: 338 VGTPPQNFTVIFDTGSSNLWVPSSKCYFSIACYLHHXXXXXXXXXXXXNGETCTISYGSG 517 +GTPPQNF V+FDTGSSNLWVPS C S AC H NG+T ++ YGSG Sbjct: 79 IGTPPQNFLVLFDTGSSNLWVPSVYCQ-SQACTGHARFNPNQSSTYSTNGQTFSLQYGSG 137 Query: 518 SIAGFFSEDSVLV 556 S+ GFF D++ V Sbjct: 138 SLTGFFGYDTMTV 150
>PEPA_RHIFE (Q9GMY7) Pepsin A precursor (EC 3.4.23.1)| Length = 386 Score = 97.1 bits (240), Expect = 3e-20 Identities = 57/153 (37%), Positives = 82/153 (53%), Gaps = 1/153 (0%) Frame = +2 Query: 104 WILSCALLLGGACSDGLLRINLSKKRLDKETLTAAKLARQETKLLRSDDGSRH-SLGLSG 280 W+L +L+ C + ++ L KK+ ++ L L + K + S++ S Sbjct: 3 WLLLLSLVALSECY--IYKVPLVKKKSLRKNLMEQGLLQDYLKTHSINPASKYLKEAASM 60 Query: 281 DDIVPLDNYLDTQYFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKCYFSIACYLHHXXXXX 460 PL+NY+D +YFG IG+GTPPQ FTVIFDTGSSNLWVPS C S AC H+ Sbjct: 61 MATQPLENYMDMEYFGTIGIGTPPQEFTVIFDTGSSNLWVPSVYC-SSPACSNHNRFNPQ 119 Query: 461 XXXXXXXNGETCTISYGSGSIAGFFSEDSVLVG 559 + +++YG+GS+ G D+V VG Sbjct: 120 QSSTYQGTNQKLSVAYGTGSMTGILGYDTVQVG 152
>PEPC_MONDO (Q689Z7) Gastricsin precursor (EC 3.4.23.3) (Pepsinogen C)| Length = 391 Score = 96.7 bits (239), Expect = 4e-20 Identities = 47/88 (53%), Positives = 57/88 (64%) Frame = +2 Query: 293 PLDNYLDTQYFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKCYFSIACYLHHXXXXXXXXX 472 P+ NYLD+ YFGEI +GTPPQNF V+FDTGSSNLWVPS+ C S AC H+ Sbjct: 66 PITNYLDSFYFGEISIGTPPQNFLVLFDTGSSNLWVPSTYCQ-SQACSNHNRFSPSQSST 124 Query: 473 XXXNGETCTISYGSGSIAGFFSEDSVLV 556 G+T T+SYGSGS+ D+V V Sbjct: 125 FTNGGQTYTLSYGSGSLTVVLGYDTVTV 152
>PAG2_BOVIN (Q28057) Pregnancy-associated glycoprotein 2 precursor (EC| 3.4.23.-) (PAG 2) Length = 376 Score = 95.9 bits (237), Expect = 7e-20 Identities = 60/152 (39%), Positives = 75/152 (49%) Frame = +2 Query: 104 WILSCALLLGGACSDGLLRINLSKKRLDKETLTAAKLARQETKLLRSDDGSRHSLGLSGD 283 W++ L+ A S+ ++ + L K + +ETL L + R S S Sbjct: 3 WLVLLGLV---ALSECIVILPLKKMKTLRETLREKNLLNN----FLEEQAYRLSKNDSKI 55 Query: 284 DIVPLDNYLDTQYFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKCYFSIACYLHHXXXXXX 463 I PL NYLDT Y G I +GTPPQ F V+FDTGS+NLWVP C S ACY H Sbjct: 56 TIHPLRNYLDTAYVGNITIGTPPQEFRVVFDTGSANLWVPCITC-TSPACYTHKTFNPQN 114 Query: 464 XXXXXXNGETCTISYGSGSIAGFFSEDSVLVG 559 G TI YGSG I GF D+V +G Sbjct: 115 SSSFREVGSPITIFYGSGIIQGFLGSDTVRIG 146
>PEPA_SUNMU (P81497) Pepsin A precursor (EC 3.4.23.1)| Length = 387 Score = 95.9 bits (237), Expect = 7e-20 Identities = 59/148 (39%), Positives = 82/148 (55%), Gaps = 3/148 (2%) Frame = +2 Query: 122 LLLG-GACSDGLLRINLSKKRLDKETLTAAKLARQETKLLRSDDGSRHSLGLSGDDIV-- 292 LLLG A S+ L ++ L KK+ ++ L L + + S++ + ++ Sbjct: 6 LLLGLVALSECLYKVPLVKKKSLRQNLIENGLLKDFLAKHNVNPASKYFPTEAATELADQ 65 Query: 293 PLDNYLDTQYFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKCYFSIACYLHHXXXXXXXXX 472 PL NY+D +YFG IG+GTPPQ FTVIFDTGSSNLWVPS C S AC H+ Sbjct: 66 PLVNYMDMEYFGTIGIGTPPQEFTVIFDTGSSNLWVPSVYC-SSPACSNHNRFNPQKSST 124 Query: 473 XXXNGETCTISYGSGSIAGFFSEDSVLV 556 +T +I+YG+GS+ G D+V V Sbjct: 125 FQSTSQTLSIAYGTGSMTGVLGYDTVQV 152
>PEPC_RABIT (Q9GMY2) Gastricsin precursor (EC 3.4.23.3) (Pepsinogen C)| Length = 388 Score = 95.9 bits (237), Expect = 7e-20 Identities = 57/149 (38%), Positives = 78/149 (52%) Frame = +2 Query: 110 LSCALLLGGACSDGLLRINLSKKRLDKETLTAAKLARQETKLLRSDDGSRHSLGLSGDDI 289 L C LL A ++++ L K + +ETL L ++ + D ++ G Sbjct: 8 LVCLHLLEAA----VIKVPLRKFKSIRETLKEKGLLKEFLNTHKYDPALKYRFGDFSVTY 63 Query: 290 VPLDNYLDTQYFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKCYFSIACYLHHXXXXXXXX 469 P+D YLD YFGEI +GTP QNF V+FDTGSSNLWVPS C S AC H+ Sbjct: 64 EPMD-YLDAAYFGEISIGTPSQNFLVLFDTGSSNLWVPSVYCQ-SEACTTHNRFNPSKSS 121 Query: 470 XXXXNGETCTISYGSGSIAGFFSEDSVLV 556 +T ++ YGSGS+ GFF D+ + Sbjct: 122 TFYTYDQTFSLEYGSGSLTGFFGYDTFTI 150
>CATE_RANCA (Q800A0) Cathepsin E precursor (EC 3.4.23.34)| Length = 397 Score = 95.5 bits (236), Expect = 9e-20 Identities = 57/139 (41%), Positives = 78/139 (56%), Gaps = 3/139 (2%) Frame = +2 Query: 149 GLLRINLSKKRLDKETLTA-AKLARQETKLLRSDDGSRHSLGLSGDDIV--PLDNYLDTQ 319 G++R+ L +++ ++ L KL+ TK + ++ + S S + PL NYLD + Sbjct: 16 GIIRVPLKRQKSMRKILKEKGKLSHLWTK--QGNEFLQLSDSCSSPETASEPLMNYLDVE 73 Query: 320 YFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKCYFSIACYLHHXXXXXXXXXXXXNGETCT 499 YFG+I +GTPPQ FTVIFDTGSSNLWVPS C S AC H+ NGE Sbjct: 74 YFGQISIGTPPQQFTVIFDTGSSNLWVPSIYC-TSQACTKHNRYRPSESTTYVSNGEAFF 132 Query: 500 ISYGSGSIAGFFSEDSVLV 556 I YG+G++ G D V V Sbjct: 133 IQYGTGNLTGILGIDQVTV 151
>CATE_CAVPO (P25796) Cathepsin E precursor (EC 3.4.23.34)| Length = 391 Score = 95.5 bits (236), Expect = 9e-20 Identities = 60/150 (40%), Positives = 77/150 (51%) Frame = +2 Query: 107 ILSCALLLGGACSDGLLRINLSKKRLDKETLTAAKLARQETKLLRSDDGSRHSLGLSGDD 286 +L LL G L R+ LS++ ++ L A Q T+L +S + + Sbjct: 6 LLLLVLLELGQAPGALHRVPLSRRESLRKKLRAQG---QLTELWKSQNLNMDQCSTIQSA 62 Query: 287 IVPLDNYLDTQYFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKCYFSIACYLHHXXXXXXX 466 PL NYLD +YFG I +G+PPQNFTVIFDTGSSNLWVPS C S AC H Sbjct: 63 NEPLINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYC-TSPACQTHPVFHPSLS 121 Query: 467 XXXXXNGETCTISYGSGSIAGFFSEDSVLV 556 G + +I YG+GS+ G D V V Sbjct: 122 STYREVGNSFSIQYGTGSLTGIIGADQVSV 151
>PEPC_RHIFE (Q9GMY3) Gastricsin precursor (EC 3.4.23.3) (Pepsinogen C)| Length = 389 Score = 95.1 bits (235), Expect = 1e-19 Identities = 56/150 (37%), Positives = 79/150 (52%) Frame = +2 Query: 107 ILSCALLLGGACSDGLLRINLSKKRLDKETLTAAKLARQETKLLRSDDGSRHSLGLSGDD 286 +L C LL ++++ L K + +ET+ L + K + D ++ Sbjct: 7 VLLCLQLLEAK----VVKVPLKKLKSLRETMKEKGLLEEFLKNHKYDPAQKYRYTDFSVA 62 Query: 287 IVPLDNYLDTQYFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKCYFSIACYLHHXXXXXXX 466 P+ Y+D YFGEI +GTPPQNF V+FDTGSSNLWVPS C + AC H Sbjct: 63 YEPMA-YMDAAYFGEISIGTPPQNFLVLFDTGSSNLWVPSVYCQ-TQACTGHTRFNPSQS 120 Query: 467 XXXXXNGETCTISYGSGSIAGFFSEDSVLV 556 NG+T ++ YGSGS+ GFF D++ V Sbjct: 121 STYSTNGQTFSLQYGSGSLTGFFGYDTLTV 150
>CARPV_CANAL (P10977) Vacuolar aspartic protease precursor (EC 3.4.23.-)| (Aspartate protease) (ACP) Length = 419 Score = 94.7 bits (234), Expect = 2e-19 Identities = 46/89 (51%), Positives = 56/89 (62%) Frame = +2 Query: 293 PLDNYLDTQYFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKCYFSIACYLHHXXXXXXXXX 472 PL NYL+ QYF EI +GTP Q F VI DTGSSNLWVPS C S+AC+LH Sbjct: 95 PLTNYLNAQYFTEIQIGTPGQPFKVILDTGSSNLWVPSQDC-TSLACFLHAKYDHDASST 153 Query: 473 XXXNGETCTISYGSGSIAGFFSEDSVLVG 559 NG +I YGSGS+ G+ S+D + +G Sbjct: 154 YKVNGSEFSIQYGSGSMEGYISQDVLTIG 182
>PAG2_PIG (Q29079) Pregnancy-associated glycoprotein 2 precursor (EC| 3.4.23.-) (PAG 2) Length = 420 Score = 94.0 bits (232), Expect = 3e-19 Identities = 57/156 (36%), Positives = 83/156 (53%), Gaps = 4/156 (2%) Frame = +2 Query: 104 WILSCALLLGGACSDGLLRINLSKKRLDKETLTAAKLARQETKL----LRSDDGSRHSLG 271 W++ L+ A SD L+ I L+K + +E+L L + K + + S++S Sbjct: 3 WLVILGLV---ALSDCLVMIPLTKVKSVRESLREKGLLKNFLKEHPYNMIQNLLSKNSSH 59 Query: 272 LSGDDIVPLDNYLDTQYFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKCYFSIACYLHHXX 451 + PL NYLD Y G I +GTPPQ F+V+FDTGSS+LWVPS C S AC H Sbjct: 60 VQKFSYQPLRNYLDMVYVGNISIGTPPQQFSVVFDTGSSDLWVPSIYCK-SKACVTHRSF 118 Query: 452 XXXXXXXXXXNGETCTISYGSGSIAGFFSEDSVLVG 559 G++ + YGSG ++GF +D+V +G Sbjct: 119 NPSHSSTFHDRGKSIKLEYGSGKMSGFLGQDTVRIG 154
>PEPA_SORUN (Q9GMY8) Pepsin A precursor (EC 3.4.23.1)| Length = 387 Score = 93.2 bits (230), Expect = 4e-19 Identities = 60/156 (38%), Positives = 86/156 (55%), Gaps = 5/156 (3%) Frame = +2 Query: 104 WILSCALLLGGACSDGLL-RINLSKKRLDKETLTAAKLARQETKLLRSDDGSRH----SL 268 W+L L+ A ++GL+ ++ L KK+ +++L L K + S++ + Sbjct: 3 WLLLLGLV---ALAEGLIHKVALVKKKSLRQSLWENGLLEDFLKTHSLNPASKYFPTEAT 59 Query: 269 GLSGDDIVPLDNYLDTQYFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKCYFSIACYLHHX 448 LS + PL NY+D +YFG I +GTPPQ FTVIFDTGSSNLWVPS C S AC H+ Sbjct: 60 TLSANQ--PLVNYMDMEYFGTISIGTPPQEFTVIFDTGSSNLWVPSIYC-SSPACSNHNR 116 Query: 449 XXXXXXXXXXXNGETCTISYGSGSIAGFFSEDSVLV 556 +T +I+YG+GS+ G D+V V Sbjct: 117 FDPQKSSTFKPTSQTVSIAYGTGSMTGVLGYDTVQV 152
>PEPE_CHICK (P16476) Embryonic pepsinogen precursor (EC 3.4.23.-)| Length = 383 Score = 92.4 bits (228), Expect = 8e-19 Identities = 59/152 (38%), Positives = 78/152 (51%), Gaps = 3/152 (1%) Frame = +2 Query: 110 LSCALLLGGACSDGLLRINLSKKRLDKETLTAAKLARQETKLLRSDDGSRHSLGLSGDDI 289 L CA+L A SDG+ R+ L + + +E L L + R D G++ Sbjct: 6 LLCAVL---ALSDGITRLPLERGKKLREILREKGLLHHFLQHHRYDIGTKFPHAFPDVLT 62 Query: 290 V---PLDNYLDTQYFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKCYFSIACYLHHXXXXX 460 V PL N LD +Y+G I +GTPPQ+FTV+FDTGSSNLWVPS C S AC H Sbjct: 63 VVTEPLLNTLDMEYYGTISIGTPPQDFTVVFDTGSSNLWVPSVSC-TSPACQSHQMFNPS 121 Query: 461 XXXXXXXNGETCTISYGSGSIAGFFSEDSVLV 556 G+ +I YG+G + G D+V V Sbjct: 122 QSSTYKSTGQNLSIHYGTGDMEGTVGCDTVTV 153
>CATE_HUMAN (P14091) Cathepsin E precursor (EC 3.4.23.34)| Length = 401 Score = 92.4 bits (228), Expect = 8e-19 Identities = 45/86 (52%), Positives = 54/86 (62%) Frame = +2 Query: 293 PLDNYLDTQYFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKCYFSIACYLHHXXXXXXXXX 472 PL NYLD +YFG I +G+PPQNFTVIFDTGSSNLWVPS C S AC H Sbjct: 69 PLINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYC-TSPACKTHSRFQPSQSST 127 Query: 473 XXXNGETCTISYGSGSIAGFFSEDSV 550 G++ +I YG+GS++G D V Sbjct: 128 YSQPGQSFSIQYGTGSLSGIIGADQV 153
>CATE_MOUSE (P70269) Cathepsin E precursor (EC 3.4.23.34)| Length = 397 Score = 91.3 bits (225), Expect = 2e-18 Identities = 47/88 (53%), Positives = 52/88 (59%) Frame = +2 Query: 293 PLDNYLDTQYFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKCYFSIACYLHHXXXXXXXXX 472 PL NYLD +YFG I +GTPPQNFTVIFDTGSSNLWVPS C S AC H Sbjct: 70 PLINYLDMEYFGTISIGTPPQNFTVIFDTGSSNLWVPSVYC-TSPACKAHPVFHPSQSDT 128 Query: 473 XXXNGETCTISYGSGSIAGFFSEDSVLV 556 G +I YG+GS+ G D V V Sbjct: 129 YTEVGNHFSIQYGTGSLTGIIGADQVSV 156
>CHYM_CALJA (Q9N2D2) Chymosin precursor (EC 3.4.23.4) (Preprorennin)| Length = 381 Score = 91.3 bits (225), Expect = 2e-18 Identities = 54/140 (38%), Positives = 75/140 (53%), Gaps = 2/140 (1%) Frame = +2 Query: 143 SDGLLRINLSKKRLDKETLTAAKLARQETKLLRSDDGSRHSLGLSGDDIVP--LDNYLDT 316 + G++RI L K + + L L K + +HS + ++ L NYLD Sbjct: 16 ASGIVRIPLHKGKSLRRALKERGLLEDFLKNHQHAVSRKHS---NSREVASEFLTNYLDC 72 Query: 317 QYFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKCYFSIACYLHHXXXXXXXXXXXXNGETC 496 QYFG+I +GTPPQ FTV+FDTGSS+LWVPS C S+AC HH ++ Sbjct: 73 QYFGKIYIGTPPQEFTVVFDTGSSDLWVPSVYCN-SVACQNHHRFDPSKSSTFQNMDKSL 131 Query: 497 TISYGSGSIAGFFSEDSVLV 556 +I YG+GS+ G D+V V Sbjct: 132 SIQYGTGSMQGLLGYDTVTV 151
>PEPB_CANFA (Q8SQ41) Pepsin B precursor (EC 3.4.23.2)| Length = 390 Score = 90.5 bits (223), Expect = 3e-18 Identities = 55/141 (39%), Positives = 76/141 (53%), Gaps = 3/141 (2%) Frame = +2 Query: 143 SDGLLRINLSKKRLDKETLTAAKLARQETKLLRSDDGSRHSLGLSGDDIV---PLDNYLD 313 S+G+ RI L K + ++ + + ET L + L +D V P NYLD Sbjct: 14 SEGVERIILKKGKSIRQVMEERGVL--ETFLRNHPKVDPAAKYLFNNDAVAYEPFTNYLD 71 Query: 314 TQYFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKCYFSIACYLHHXXXXXXXXXXXXNGET 493 + YFGEI +GTPPQNF ++FDTGSSNLWVPS+ C S AC H+ + +T Sbjct: 72 SYYFGEISIGTPPQNFLILFDTGSSNLWVPSTYCQ-SQACSNHNRFNPSRSSTYQSSEQT 130 Query: 494 CTISYGSGSIAGFFSEDSVLV 556 T++YG GS+ D+V V Sbjct: 131 YTLAYGFGSLTVLLGYDTVTV 151
>PEPA_CANFA (Q9GMY6) Pepsin A precursor (EC 3.4.23.1)| Length = 386 Score = 90.5 bits (223), Expect = 3e-18 Identities = 45/88 (51%), Positives = 54/88 (61%) Frame = +2 Query: 296 LDNYLDTQYFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKCYFSIACYLHHXXXXXXXXXX 475 L NY+D +YFG IG+GTPPQ FTVIFDTGSSNLWVPS C S AC H+ Sbjct: 66 LKNYMDMEYFGTIGIGTPPQEFTVIFDTGSSNLWVPSVYC-SSPACSNHNRFNPQESSTY 124 Query: 476 XXNGETCTISYGSGSIAGFFSEDSVLVG 559 +I+YG+GS+ G D+V VG Sbjct: 125 QGTNRPVSIAYGTGSMTGILGYDTVQVG 152
>CATE_RABIT (P43159) Cathepsin E precursor (EC 3.4.23.34)| Length = 396 Score = 88.2 bits (217), Expect = 1e-17 Identities = 45/88 (51%), Positives = 53/88 (60%) Frame = +2 Query: 293 PLDNYLDTQYFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKCYFSIACYLHHXXXXXXXXX 472 PL NYLD +YFG I +G+PPQNFTVIFDT SSNLWVPS C S AC +H Sbjct: 69 PLINYLDMEYFGTISIGSPPQNFTVIFDTVSSNLWVPSVYC-TSPACQMHPQFRPSQSNT 127 Query: 473 XXXNGETCTISYGSGSIAGFFSEDSVLV 556 G +I+YG+GS+ G D V V Sbjct: 128 YSEVGTPFSIAYGTGSLTGIIGADQVSV 155
>CHYM_BOVIN (P00794) Chymosin precursor (EC 3.4.23.4) (Preprorennin)| Length = 381 Score = 88.2 bits (217), Expect = 1e-17 Identities = 58/153 (37%), Positives = 77/153 (50%) Frame = +2 Query: 98 CLWILSCALLLGGACSDGLLRINLSKKRLDKETLTAAKLARQETKLLRSDDGSRHSLGLS 277 CL +L L + RI L K + ++ L L + + S++S G Sbjct: 3 CLVVLLAVFALSQGAE--ITRIPLYKGKSLRKALKEHGLLEDFLQKQQYGISSKYS-GFG 59 Query: 278 GDDIVPLDNYLDTQYFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKCYFSIACYLHHXXXX 457 VPL NYLD+QYFG+I +GTPPQ FTV+FDTGSS+ WVPS C S AC H Sbjct: 60 EVASVPLTNYLDSQYFGKIYLGTPPQEFTVLFDTGSSDFWVPSIYCK-SNACKNHQRFDP 118 Query: 458 XXXXXXXXNGETCTISYGSGSIAGFFSEDSVLV 556 G+ +I YG+GS+ G D+V V Sbjct: 119 RKSSTFQNLGKPLSIHYGTGSMQGILGYDTVTV 151
>CHYM_SHEEP (P18276) Chymosin precursor (EC 3.4.23.4) (Preprorennin)| Length = 381 Score = 87.8 bits (216), Expect = 2e-17 Identities = 45/89 (50%), Positives = 55/89 (61%) Frame = +2 Query: 290 VPLDNYLDTQYFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKCYFSIACYLHHXXXXXXXX 469 VPL NYLD+QYFG+I +GTPPQ FTV+FDTGSS+ WVPS C S AC H Sbjct: 64 VPLTNYLDSQYFGKIYLGTPPQEFTVLFDTGSSDFWVPSIYCK-SNACKNHQRFDPRKSS 122 Query: 470 XXXXNGETCTISYGSGSIAGFFSEDSVLV 556 G+ +I YG+GS+ G D+V V Sbjct: 123 TFQNLGKPLSIRYGTGSMQGILGYDTVTV 151
>PEPA_CHICK (P00793) Pepsin A precursor (EC 3.4.23.1)| Length = 367 Score = 86.7 bits (213), Expect = 4e-17 Identities = 43/99 (43%), Positives = 57/99 (57%) Frame = +2 Query: 260 HSLGLSGDDIVPLDNYLDTQYFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKCYFSIACYL 439 H + + + P+ NY+D Y+G I +GTP Q+F+VIFDTGSSNLWVPS C S AC Sbjct: 39 HPVLTATESYEPMTNYMDASYYGTISIGTPQQDFSVIFDTGSSNLWVPSIYCK-SSACSN 97 Query: 440 HHXXXXXXXXXXXXNGETCTISYGSGSIAGFFSEDSVLV 556 H ET I+YG+GS++G D+V V Sbjct: 98 HKRFDPSKSSTYVSTNETVYIAYGTGSMSGILGYDTVAV 136
>CATE_RAT (P16228) Cathepsin E precursor (EC 3.4.23.34)| Length = 398 Score = 86.3 bits (212), Expect = 5e-17 Identities = 44/88 (50%), Positives = 51/88 (57%) Frame = +2 Query: 293 PLDNYLDTQYFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKCYFSIACYLHHXXXXXXXXX 472 PL NYLD +YFG + +G+P QNFTVIFDTGSSNLWVPS C S AC H Sbjct: 71 PLINYLDMEYFGTVSIGSPSQNFTVIFDTGSSNLWVPSVYC-TSPACKAHPVFHPSQSST 129 Query: 473 XXXNGETCTISYGSGSIAGFFSEDSVLV 556 G +I YG+GS+ G D V V Sbjct: 130 YMEVGNHFSIQYGTGSLTGIIGADQVSV 157
>PAG_HORSE (Q28389) Pregnancy-associated glycoprotein precursor (EC 3.4.23.-)| (PAG) Length = 388 Score = 86.3 bits (212), Expect = 5e-17 Identities = 61/160 (38%), Positives = 78/160 (48%) Frame = +2 Query: 77 MPFLGVTCLWILSCALLLGGACSDGLLRINLSKKRLDKETLTAAKLARQETKLLRSDDGS 256 M + GV L LS L+ LR NL +K + KE L R KLL Sbjct: 1 MKWFGVLGLVTLSECLVTIPLVKIKSLRENLREKDMLKEYLEKYPF-RLTHKLL------ 53 Query: 257 RHSLGLSGDDIVPLDNYLDTQYFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKCYFSIACY 436 H SG P+ NYLD Y G I VGTPPQ F VIFDTGS++LWVPS C S AC Sbjct: 54 -HKHADSGVAFEPMRNYLDIAYMGIISVGTPPQEFQVIFDTGSADLWVPSIYC-SSPACS 111 Query: 437 LHHXXXXXXXXXXXXNGETCTISYGSGSIAGFFSEDSVLV 556 H+ +G+ + YG+G ++GF D++ + Sbjct: 112 NHNTFNPLRSSTFVASGQPIKLIYGTGKMSGFVGYDTIKI 151
>ASP3_CAEEL (P55956) Aspartic protease 3 precursor (EC 3.4.23.-)| Length = 398 Score = 84.7 bits (208), Expect = 2e-16 Identities = 40/89 (44%), Positives = 52/89 (58%), Gaps = 1/89 (1%) Frame = +2 Query: 296 LDNYLDTQYFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKCYF-SIACYLHHXXXXXXXXX 472 L +Y + QY+G + +GTPPQNF V+FDTGSSNLWVP + C F IAC +H+ Sbjct: 61 LSDYSNAQYYGPVTIGTPPQNFQVLFDTGSSNLWVPCANCPFGDIACRMHNRFDCKKSSS 120 Query: 473 XXXNGETCTISYGSGSIAGFFSEDSVLVG 559 G + I YG+GS+ G D V G Sbjct: 121 CTATGASFEIQYGTGSMKGTVDNDVVCFG 149
>PEPC_CAVPO (Q64411) Gastricsin precursor (EC 3.4.23.3) (Pepsinogen C)| Length = 394 Score = 84.0 bits (206), Expect = 3e-16 Identities = 42/102 (41%), Positives = 61/102 (59%), Gaps = 2/102 (1%) Frame = +2 Query: 257 RHSLGLSGDDIVPLD--NYLDTQYFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKCYFSIA 430 R+ L +GD V + +Y+D YFG+I +GTPPQ+F V+FDTGSSNLWVPS C S+A Sbjct: 56 RNRLAKTGDFSVLYEPMSYMDAAYFGQISLGTPPQSFQVLFDTGSSNLWVPSVYC-SSLA 114 Query: 431 CYLHHXXXXXXXXXXXXNGETCTISYGSGSIAGFFSEDSVLV 556 C H ++ ++ YG+GS+ G F D++ + Sbjct: 115 CTTHTRFNPRDSSTYVATDQSFSLEYGTGSLTGVFGYDTMTI 156
>PEP2B_GADMO (P56272) Pepsin IIB (EC 3.4.23.-)| Length = 324 Score = 82.0 bits (201), Expect = 1e-15 Identities = 39/88 (44%), Positives = 54/88 (61%) Frame = +2 Query: 296 LDNYLDTQYFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKCYFSIACYLHHXXXXXXXXXX 475 + N DT+Y+G I +GTPP++F VIFDTGSSNLWV SS C + AC H+ Sbjct: 6 MKNEADTEYYGVISIGTPPESFKVIFDTGSSNLWVSSSHC-SAQACSNHNKFKPRQSSTY 64 Query: 476 XXNGETCTISYGSGSIAGFFSEDSVLVG 559 G+T ++YG+G + G +D+V VG Sbjct: 65 VETGKTVDLTYGTGGMRGILGQDTVSVG 92
>PEPAF_RABIT (P27823) Pepsin F precursor (EC 3.4.23.1)| Length = 388 Score = 80.1 bits (196), Expect = 4e-15 Identities = 40/88 (45%), Positives = 51/88 (57%) Frame = +2 Query: 293 PLDNYLDTQYFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKCYFSIACYLHHXXXXXXXXX 472 PL NYLD Y G I +GTPPQ F V+ DTGS++LWVPS C S AC H+ Sbjct: 65 PLRNYLDLAYIGIISIGTPPQEFKVVLDTGSADLWVPSIYC-SSPACGKHNTFNPLLSST 123 Query: 473 XXXNGETCTISYGSGSIAGFFSEDSVLV 556 +G I YGSG ++GF + D+V + Sbjct: 124 FLVSGRPINIVYGSGRMSGFLAYDTVQI 151
>PAG1_PIG (Q29078) Pregnancy-associated glycoprotein 1 precursor (EC| 3.4.23.-) (PAG 1) Length = 389 Score = 77.4 bits (189), Expect = 3e-14 Identities = 52/156 (33%), Positives = 78/156 (50%), Gaps = 4/156 (2%) Frame = +2 Query: 104 WILSCALLLGGACSDGLLRINLSKKRLDKETLTAAKLA----RQETKLLRSDDGSRHSLG 271 W++ L+ A S+ L+ I L+K + +E L L ++ + G + SL Sbjct: 3 WLVILGLV---ALSECLVIIPLTKVKSIRENLREKDLLLNFLKEHPYNMIQKFGLKGSLC 59 Query: 272 LSGDDIVPLDNYLDTQYFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKCYFSIACYLHHXX 451 + L NYLD Y G I +GTPPQ F+VIFDT SS+LWVPS++C+ S AC H Sbjct: 60 SPKISCLRLWNYLDMVYVGNITIGTPPQLFSVIFDTASSDLWVPSNQCH-SRACVTHRSF 118 Query: 452 XXXXXXXXXXNGETCTISYGSGSIAGFFSEDSVLVG 559 + T ++ SG ++G D+V +G Sbjct: 119 NPTLSSTFQSSNRTVKLAPHSGLVSGLLGYDTVQIG 154
>PAG1_BOVIN (Q29432) Pregnancy-associated glycoprotein 1 precursor (EC| 3.4.23.-) (PAG 1) (Pregnancy-specific protein B) (PSP-B) Length = 380 Score = 75.1 bits (183), Expect = 1e-13 Identities = 48/154 (31%), Positives = 73/154 (47%), Gaps = 2/154 (1%) Frame = +2 Query: 104 WILSCALLLGGACSDGLLRINLSKKRLDKETLTAAKLARQETKLLRSDDGSRHSLGLSGD 283 W++ L+ A S+ +++I L + + + ++ + L+ S + G Sbjct: 3 WLVLLGLV---AFSECIVKIPLRRLKTMRNVVSGKNMLNN---FLKEHAYSLSQISFRGS 56 Query: 284 DIV--PLDNYLDTQYFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKCYFSIACYLHHXXXX 457 ++ PL N D Y G I +GTPPQ F V+FDT SS+LWVPS C S AC H Sbjct: 57 NLTTHPLRNIKDLVYMGNITIGTPPQEFQVVFDTASSDLWVPSDFC-TSPACSTHVRFRH 115 Query: 458 XXXXXXXXNGETCTISYGSGSIAGFFSEDSVLVG 559 +T I+YGSG + G D+V +G Sbjct: 116 LQSSTFRLTNKTFRITYGSGRMKGVVVHDTVRIG 149
>PAG1_SHEEP (Q28755) Pregnancy-associated glycoprotein 1 precursor (EC| 3.4.23.-) (PAG 1) Length = 382 Score = 73.6 bits (179), Expect = 4e-13 Identities = 50/154 (32%), Positives = 75/154 (48%), Gaps = 2/154 (1%) Frame = +2 Query: 104 WILSCALLLGGACSDGLLRINLSKKRLDKETLTAAKLARQETKLLRSDDGSRHSLGLSGD 283 W++ L+ A S+ +++I L + + + TL+ K+ K + S+ S S Sbjct: 3 WLVLLGLV---AFSECIVKIPLRRVKTMRNTLSGKKMLNSFLKE-HAYRLSQISFRASNL 58 Query: 284 DIVPLDNYLDTQYFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKCYFSI--ACYLHHXXXX 457 I PL N +D Y G I +GTPPQ F V+FDTGSS+L VPS C C Sbjct: 59 TIHPLRNIMDMLYVGNITIGTPPQEFQVVFDTGSSDLLVPSINCLSPTKRPCSKQDKFKH 118 Query: 458 XXXXXXXXNGETCTISYGSGSIAGFFSEDSVLVG 559 +T I +GSG++ GF + D+V +G Sbjct: 119 HQSSTFRFTNDTFRIYFGSGTMRGFVAHDTVRIG 152
>PLM2_PLAFA (P46925) Plasmepsin-2 precursor (EC 3.4.23.39) (Aspartic| hemoglobinase II) (PFAPD) Length = 453 Score = 72.8 bits (177), Expect = 6e-13 Identities = 41/114 (35%), Positives = 60/114 (52%) Frame = +2 Query: 218 RQETKLLRSDDGSRHSLGLSGDDIVPLDNYLDTQYFGEIGVGTPPQNFTVIFDTGSSNLW 397 ++ L S + LG S D+I +D + + ++G+ VG Q FT I DTGS+NLW Sbjct: 107 KESVNFLNSGLTKTNYLGSSNDNIELVD-FQNIMFYGDAEVGDNQQPFTFILDTGSANLW 165 Query: 398 VPSSKCYFSIACYLHHXXXXXXXXXXXXNGETCTISYGSGSIAGFFSEDSVLVG 559 VPS KC + C H +G ++Y SG+++GFFS+D V VG Sbjct: 166 VPSVKC-TTAGCLTKHLYDSSKSRTYEKDGTKVEMNYVSGTVSGFFSKDLVTVG 218
>PLM1_PLAFA (P39898) Plasmepsin-1 precursor (EC 3.4.23.38) (Aspartic| hemoglobinase I) (PfAPG) Length = 452 Score = 72.4 bits (176), Expect = 8e-13 Identities = 37/113 (32%), Positives = 62/113 (54%) Frame = +2 Query: 218 RQETKLLRSDDGSRHSLGLSGDDIVPLDNYLDTQYFGEIGVGTPPQNFTVIFDTGSSNLW 397 ++ K ++ + LG +GD + L++ + Y+GE +G Q F IFDTGS+NLW Sbjct: 106 KESLKFFKTGLTQKPHLGNAGDSVT-LNDVANVMYYGEAQIGDNKQKFAFIFDTGSANLW 164 Query: 398 VPSSKCYFSIACYLHHXXXXXXXXXXXXNGETCTISYGSGSIAGFFSEDSVLV 556 VPS++C +I C + +G ++Y SG+++GFFS+D V + Sbjct: 165 VPSAQCN-TIGCKTKNLYDSNKSKTYEKDGTKVEMNYVSGTVSGFFSKDIVTI 216
>PLM1_PLAF7 (Q7KQM4) Plasmepsin-1 precursor (EC 3.4.23.38) (Aspartic| hemoglobinase I) (PfAPG) Length = 452 Score = 72.4 bits (176), Expect = 8e-13 Identities = 37/113 (32%), Positives = 62/113 (54%) Frame = +2 Query: 218 RQETKLLRSDDGSRHSLGLSGDDIVPLDNYLDTQYFGEIGVGTPPQNFTVIFDTGSSNLW 397 ++ K ++ + LG +GD + L++ + Y+GE +G Q F IFDTGS+NLW Sbjct: 106 KESLKFFKTGLTQKPHLGNAGDSVT-LNDVANVMYYGEAQIGDNKQKFAFIFDTGSANLW 164 Query: 398 VPSSKCYFSIACYLHHXXXXXXXXXXXXNGETCTISYGSGSIAGFFSEDSVLV 556 VPS++C +I C + +G ++Y SG+++GFFS+D V + Sbjct: 165 VPSAQCN-TIGCKTKNLYDSNKSKTYEKDGTKVEMNYVSGTVSGFFSKDIVTI 216
>CARP5_RHINI (P43232) Rhizopuspepsin-5 precursor (EC 3.4.23.21) (Aspartate| protease) Length = 392 Score = 62.8 bits (151), Expect = 6e-10 Identities = 41/109 (37%), Positives = 54/109 (49%), Gaps = 2/109 (1%) Frame = +2 Query: 239 RSDDGSRHSLGLSGDDIVPL-DNYLDTQYFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKC 415 RS S +S G VP+ D Y D +YFG++ VGTP + FDTGSS+LW SS C Sbjct: 57 RSTSSSSNSTSTDGIGRVPVTDYYNDIEYFGQVKVGTPGVTLKLDFDTGSSDLWFASSLC 116 Query: 416 YFSIACYLHHXXXXXXXXXXXXNGETCTISYGSGSIA-GFFSEDSVLVG 559 + Y +G +ISYG GS A G D+V++G Sbjct: 117 --TNCGYSQTKYNPNQSRTYAKDGRAWSISYGDGSSASGILGTDTVVLG 163
>CARP4_RHINI (Q03700) Rhizopuspepsin-4 precursor (EC 3.4.23.21) (Aspartate| protease) Length = 398 Score = 62.0 bits (149), Expect = 1e-09 Identities = 51/163 (31%), Positives = 73/163 (44%), Gaps = 8/163 (4%) Frame = +2 Query: 95 TCLWILSCALLLGGACSDGLLRINLSKKRLDKETLTAA------KLARQETKLLRSDDGS 256 +C+ + AL + A S + + LSK K A K AR + S S Sbjct: 8 SCVALACMALAVEAAPSGKKINVPLSKNANYKPNAKRAIEKANAKYARFRSSSSSSSSSS 67 Query: 257 RHSLGLSGDDIVPL-DNYLDTQYFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKCYFSIAC 433 S G VP+ D+ D +Y+GE+ VGTP + FDTGSS+LW S+ C + Sbjct: 68 CGSAGTESSGSVPVTDDGNDIEYYGEVTVGTPGIKLKLDFDTGSSDLWFASTLCTNCGSS 127 Query: 434 YLHHXXXXXXXXXXXXNGETCTISYGSGSIA-GFFSEDSVLVG 559 + +G T +ISYG GS A G +D+V +G Sbjct: 128 QTKY--DPSQSSTYAKDGRTWSISYGDGSSASGILGKDTVNLG 168
>CARP_RHIMI (P00799) Mucorpepsin precursor (EC 3.4.23.23) (Mucor rennin)| Length = 430 Score = 61.6 bits (148), Expect = 1e-09 Identities = 44/163 (26%), Positives = 66/163 (40%), Gaps = 13/163 (7%) Frame = +2 Query: 110 LSCALLLGGACSDGLLRINLSKKRLDKETLTAAKLARQETKLLRSDDGSRHSL----GLS 277 ++ A+LL A +SK+ K+ L A L K ++ G + GL Sbjct: 6 ITSAILLTAASLSLTTARPVSKQSESKDKLLALPLTSVSRKFSQTKFGQQQLAEKLAGLK 65 Query: 278 GDDIVPLDNYLDT---------QYFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKCYFSIA 430 D +DT +Y + +GTP Q+F ++FDTGSS+ WVP C S Sbjct: 66 PFSEAAADGSVDTPGYYDFDLEEYAIPVSIGTPGQDFLLLFDTGSSDTWVPHKGCTKSEG 125 Query: 431 CYLHHXXXXXXXXXXXXNGETCTISYGSGSIAGFFSEDSVLVG 559 C I+YG+G G + EDS+ +G Sbjct: 126 CVGSRFFDPSASSTFKATNYNLNITYGTGGANGLYFEDSIAIG 168
>CARP_RHICH (P06026) Rhizopuspepsin precursor (EC 3.4.23.21)| Length = 393 Score = 61.6 bits (148), Expect = 1e-09 Identities = 48/162 (29%), Positives = 78/162 (48%), Gaps = 7/162 (4%) Frame = +2 Query: 95 TCLWILSCALLLGGACSDGLLRINLSK----KRLDKETLTAAKLARQETKLLRSDDGSRH 262 +C+ I + A+ + A + + I L+K K K + A + K+ S G Sbjct: 8 SCIAIAALAVAVDAAPGEKKISIPLAKNPNYKPSAKNAIQKAIAKYNKHKINTSTGGIVP 67 Query: 263 SLGLSGDDIVPLDNY-LDTQYFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKCYFSIACYL 439 G+ VP+ +Y D +Y+G++ +GTP + F + FDTGSS+LW+ S+ C C Sbjct: 68 DAGVG---TVPMTDYGNDVEYYGQVTIGTPGKKFNLDFDTGSSDLWIASTLC---TNCGS 121 Query: 440 HHXXXX-XXXXXXXXNGETCTISYGSGSIA-GFFSEDSVLVG 559 +G T +ISYG GS A G ++D+V +G Sbjct: 122 RQTKYDPKQSSTYQADGRTWSISYGDGSSASGILAKDNVNLG 163
>CARP3_RHINI (Q03699) Rhizopuspepsin-3 precursor (EC 3.4.23.21) (Aspartate| protease) Length = 391 Score = 60.5 bits (145), Expect = 3e-09 Identities = 39/104 (37%), Positives = 53/104 (50%), Gaps = 2/104 (1%) Frame = +2 Query: 254 SRHSLGLSGDDIVPL-DNYLDTQYFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKCYFSIA 430 S +S G VP+ D Y D +Y+GE+ VGTP + FDTGSS+LW SS C + Sbjct: 61 SSNSTSTDGIGYVPVTDYYNDIEYYGEVTVGTPGVTLKLDFDTGSSDLWFASSLCTNCGS 120 Query: 431 CYLHHXXXXXXXXXXXXNGETCTISYGSGSIA-GFFSEDSVLVG 559 + +G T +ISYG GS A G D+V++G Sbjct: 121 SQTKY--NPNESSTYARDGRTWSISYGDGSSASGILGTDTVILG 162
>CARP1_RHINI (P10602) Rhizopuspepsin-1 precursor (EC 3.4.23.21) (Aspartate| protease) Length = 389 Score = 59.3 bits (142), Expect = 7e-09 Identities = 46/156 (29%), Positives = 71/156 (45%), Gaps = 1/156 (0%) Frame = +2 Query: 95 TCLWILSCALLLGGACSDGLLRINLSKKRLDKETLTAAKLARQETKLLRSDDGSRHSLGL 274 +C+ + + L + A + + I L+K K + A L + K R GS Sbjct: 8 SCVALAAMTLAVEAAPNGKKINIPLAKNNSYKPSAKNA-LNKALAKYNRRKVGSGGITTE 66 Query: 275 SGDDIVPLDNYLDTQYFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKCYFSIACYLHHXXX 454 + + +D D +Y+GE+ VGTP + FDTGSS++W S+ C S H Sbjct: 67 ASGSVPMVDYENDVEYYGEVTVGTPGIKLKLDFDTGSSDMWFASTLC--SSCSNSHTKYD 124 Query: 455 XXXXXXXXXNGETCTISYGSGSIA-GFFSEDSVLVG 559 +G T +ISYG GS A G + D+V +G Sbjct: 125 PKKSSTYAADGRTWSISYGDGSSASGILATDNVNLG 160
>CARP2_RHINI (P43231) Rhizopuspepsin-2 precursor (EC 3.4.23.21) (Aspartate| protease) Length = 391 Score = 58.2 bits (139), Expect = 2e-08 Identities = 50/158 (31%), Positives = 73/158 (46%), Gaps = 3/158 (1%) Frame = +2 Query: 95 TCLWILSCALLLGGACSDGLLRINLSKKRLDKETL-TAAKLARQETKLLRSDDGSRHSLG 271 +C+ + AL A S L I L+K K + A + A + R+ S +S Sbjct: 8 SCVALAFMALATEAAPSGKKLSIPLTKNTNYKPSAKNAIQKALAKYHRFRTTSSS-NSTS 66 Query: 272 LSGDDIVPL-DNYLDTQYFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKCYFSIACYLHHX 448 G VP+ D Y D +Y+G++ VGTP + FDTGSS+LW S+ C + + Sbjct: 67 TEGTGSVPVTDYYNDIEYYGKVTVGTPGVTLKLDFDTGSSDLWFASTLCTNCGSSQTKY- 125 Query: 449 XXXXXXXXXXXNGETCTISYGSGSIA-GFFSEDSVLVG 559 +G T +ISYG GS A G D+V +G Sbjct: 126 -NPNQSSTYAKDGRTWSISYGDGSSASGILGTDTVTLG 162
>CARP_RHIPU (P09177) Mucorpepsin precursor (EC 3.4.23.23) (Mucor rennin)| Length = 427 Score = 57.4 bits (137), Expect = 3e-08 Identities = 34/110 (30%), Positives = 47/110 (42%) Frame = +2 Query: 230 KLLRSDDGSRHSLGLSGDDIVPLDNYLDTQYFGEIGVGTPPQNFTVIFDTGSSNLWVPSS 409 K DGS + GL D+ +Y + +GTP Q+F ++FDTGSS+ WVP Sbjct: 64 KAFAEGDGSVDTPGLYDFDL--------EEYAIPVSIGTPGQDFYLLFDTGSSDTWVPHK 115 Query: 410 KCYFSIACYLHHXXXXXXXXXXXXNGETCTISYGSGSIAGFFSEDSVLVG 559 C S C I+YG+G G + DS+ VG Sbjct: 116 GCDNSEGCVGKRFFDPSSSSTFKETDYNLNITYGTGGANGIYFRDSITVG 165
>CARP_SYNRA (P81214) Syncephapepsin precursor (EC 3.4.23.-)| Length = 395 Score = 50.4 bits (119), Expect = 3e-06 Identities = 35/97 (36%), Positives = 49/97 (50%), Gaps = 2/97 (2%) Frame = +2 Query: 275 SGDDIVPL-DNYLDTQYFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKCYFSIACYLHHXX 451 SG VP+ D D +Y+ + VGTP Q+ + FDTGSS+LW S+ C +C Sbjct: 73 SGTGSVPMTDVDYDVEYYATVSVGTPAQSIKLDFDTGSSDLWFSSTLC---TSCG-SKSF 128 Query: 452 XXXXXXXXXXNGETCTISYGSGSIA-GFFSEDSVLVG 559 G++ ISYG GS A G + D+V +G Sbjct: 129 DPTKSSTYKKVGKSWQISYGDGSSASGITATDNVELG 165
>CARP_CRYPA (P11838) Endothiapepsin precursor (EC 3.4.23.22) (Aspartate| protease) Length = 419 Score = 50.1 bits (118), Expect = 4e-06 Identities = 34/90 (37%), Positives = 45/90 (50%), Gaps = 1/90 (1%) Frame = +2 Query: 293 PLDNYLDTQYFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKCYFSIACYLHHXXXXXXXXX 472 P+D+ LD Y + +GTP Q + FDTGSS+LWV SS+ S Sbjct: 98 PIDS-LDDAYITPVQIGTPAQTLNLDFDTGSSDLWVFSSETTASEVDGQTIYTPSKSTTA 156 Query: 473 XXXNGETCTISYGSG-SIAGFFSEDSVLVG 559 +G T +ISYG G S +G D+V VG Sbjct: 157 KLLSGATWSISYGDGSSSSGDVYTDTVSVG 186
>CARP_IRPLA (P17576) Polyporopepsin (EC 3.4.23.29) (Aspartic proteinase)| Length = 340 Score = 48.9 bits (115), Expect = 1e-05 Identities = 27/90 (30%), Positives = 42/90 (46%) Frame = +2 Query: 290 VPLDNYLDTQYFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKCYFSIACYLHHXXXXXXXX 469 VP N L Y +GVG+P ++++ DTGSSN W+ + K Y Sbjct: 5 VPATNQL-VDYVVNVGVGSPATTYSLLVDTGSSNTWLGADKSYVK-------------TS 50 Query: 470 XXXXNGETCTISYGSGSIAGFFSEDSVLVG 559 + +++YGSGS +G D+V +G Sbjct: 51 TSSATSDKVSVTYGSGSFSGTEYTDTVTLG 80
>CARP4_CANAL (P43093) Candidapepsin-4 precursor (EC 3.4.23.24) (Aspartate| protease 4) (ACP 4) (Secreted aspartic protease 4) Length = 417 Score = 48.5 bits (114), Expect = 1e-05 Identities = 26/55 (47%), Positives = 34/55 (61%) Frame = +2 Query: 245 DDGSRHSLGLSGDDIVPLDNYLDTQYFGEIGVGTPPQNFTVIFDTGSSNLWVPSS 409 DD R+ +G G V LDN + T Y +I +G+ Q +VI DTGSS+LWVP S Sbjct: 65 DDTGRNDVGKRGPVAVKLDNEIIT-YSADITIGSNNQKLSVIVDTGSSDLWVPDS 118
>CARP6_CANAL (P43095) Candidapepsin-6 precursor (EC 3.4.23.24) (Aspartate| protease 6) (ACP 6) (Secreted aspartic protease 6) Length = 418 Score = 45.8 bits (107), Expect = 8e-05 Identities = 39/115 (33%), Positives = 56/115 (48%), Gaps = 11/115 (9%) Frame = +2 Query: 101 LWILSCALLLGGAC---SDGLLRINLSKKRL----DKETLTAAK----LARQETKLLRSD 247 L +L ALL+ A S G + ++ + KR D T + + L T++ D Sbjct: 7 LSVLRFALLIDAAPVKRSPGFVTLDFNVKRSLVVPDDPTAESKRSPLFLDLDPTQIPVDD 66 Query: 248 DGSRHSLGLSGDDIVPLDNYLDTQYFGEIGVGTPPQNFTVIFDTGSSNLWVPSSK 412 G + G V LDN + T Y +I VG+ Q +VI DTGSS+LW+P SK Sbjct: 67 TGRNVGVDKRGPVAVKLDNEIIT-YSADITVGSNNQKLSVIVDTGSSDLWIPDSK 120
>PEPC_PIG (P30879) Gastricsin precursor (EC 3.4.23.3) (Pepsinogen C)| (Fragment) Length = 73 Score = 45.4 bits (106), Expect = 1e-04 Identities = 23/73 (31%), Positives = 40/73 (54%) Frame = +2 Query: 152 LLRINLSKKRLDKETLTAAKLARQETKLLRSDDGSRHSLGLSGDDIVPLDNYLDTQYFGE 331 ++++ L K + ++ + L + K + D R+ +G + P+ YL+ YFGE Sbjct: 2 VIKVPLKKLKSIRQAMKEKGLLEEFLKTHKYDPAQRYRIGDISVALEPMA-YLEAAYFGE 60 Query: 332 IGVGTPPQNFTVI 370 I +GTPPQNF V+ Sbjct: 61 ISIGTPPQNFLVL 73
>BACE2_HUMAN (Q9Y5Z0) Beta-secretase 2 precursor (EC 3.4.23.45) (Beta-site| APP-cleaving enzyme 2) (Aspartyl protease 1) (Asp 1) (ASP1) (Membrane-associated aspartic protease 1) (Memapsin-1) (Down region aspartic protease) Length = 518 Score = 43.9 bits (102), Expect = 3e-04 Identities = 25/79 (31%), Positives = 34/79 (43%) Frame = +2 Query: 320 YFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKCYFSIACYLHHXXXXXXXXXXXXNGETCT 499 Y+ E+ +GTPPQ ++ DTGSSN V + Y+ G T Sbjct: 92 YYLEMLIGTPPQKLQILVDTGSSNFAVAGTP-----HSYIDTYFDTERSSTYRSKGFDVT 146 Query: 500 ISYGSGSIAGFFSEDSVLV 556 + Y GS GF ED V + Sbjct: 147 VKYTQGSWTGFVGEDLVTI 165
>YPS3_YEAST (Q12303) Aspartic proteinase yapsin-3 precursor (EC 3.4.23.-)| Length = 508 Score = 43.5 bits (101), Expect = 4e-04 Identities = 27/82 (32%), Positives = 39/82 (47%), Gaps = 5/82 (6%) Frame = +2 Query: 320 YFGEIGVGTPPQNFTVIFDTGSSNLWVP---SSKCYFSIACYLHHXXXXXXXXXXXXN-G 487 Y E+ +GTP QN TV+ DTGS++LWVP + C + C + N Sbjct: 63 YSVELAIGTPSQNLTVLLDTGSADLWVPGKGNPYCGSVMDCDQYGVFDKTKSSTFKANKS 122 Query: 488 ETCTISYGSGSIA-GFFSEDSV 550 +YG G+ A G F +D + Sbjct: 123 SPFYAAYGDGTYAEGAFGQDKL 144
>CARP_PODAN (O13340) Podosporapepsin precursor (EC 3.4.23.-)| Length = 425 Score = 43.5 bits (101), Expect = 4e-04 Identities = 25/73 (34%), Positives = 33/73 (45%) Frame = +2 Query: 302 NYLDTQYFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKCYFSIACYLHHXXXXXXXXXXXX 481 N +D Y + +GTPPQ + DTGSS+LWV SS + Sbjct: 102 NEVDIAYVTPVTIGTPPQTLMLDLDTGSSDLWVFSSLTPSNQVRGQEIYSPTKSSTSKLL 161 Query: 482 NGETCTISYGSGS 520 +G T +I YG GS Sbjct: 162 SGHTWSIRYGDGS 174
>CARP_SACFI (P22929) Acid protease precursor (EC 3.4.23.-)| Length = 390 Score = 43.5 bits (101), Expect = 4e-04 Identities = 35/109 (32%), Positives = 49/109 (44%), Gaps = 3/109 (2%) Frame = +2 Query: 242 SDDGSRHSLGLSGDD--IVPLDNYLDTQYFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKC 415 S G R +L + D + L+N Y I +GTP Q V DTGSS+LWVP Sbjct: 48 SSPGFRRNLRAASDAGVTISLENEYSF-YLTTIEIGTPGQKLQVDVDTGSSDLWVPGQGT 106 Query: 416 YFSIACYLHHXXXXXXXXXXXXNGETCTISYGSGSIA-GFFSEDSVLVG 559 Y H + +ISYG GS A G +++++V +G Sbjct: 107 SSLYGTYDH-----TKSTSYKKDRSGFSISYGDGSSARGDWAQETVSIG 150
>CARP1_CANPA (P32951) Candidapepsin-1 precursor (EC 3.4.23.24) (Aspartate| protease 1) (ACP 1) Length = 402 Score = 43.5 bits (101), Expect = 4e-04 Identities = 27/82 (32%), Positives = 38/82 (46%), Gaps = 3/82 (3%) Frame = +2 Query: 320 YFGEIGVGTPPQNFTVIFDTGSSNLWVPSS--KCYFSIACYLHHXXXXXXXXXXXXNGET 493 Y ++ VG+ Q TVI DTGSS+ WV S +C + C G Sbjct: 76 YASKVSVGSNKQQQTVIIDTGSSDFWVVDSNAQCGKGVDCKSSGTFTPSSSSSYKNLGAA 135 Query: 494 CTISYGSGSIA-GFFSEDSVLV 556 TI YG GS + G + +D+V + Sbjct: 136 FTIRYGDGSTSQGTWGKDTVTI 157
>MKC7_YEAST (P53379) Aspartic proteinase MKC7 precursor (EC 3.4.23.41) (Yapsin| 2) Length = 596 Score = 43.1 bits (100), Expect = 5e-04 Identities = 21/42 (50%), Positives = 29/42 (69%) Frame = +2 Query: 284 DIVPLDNYLDTQYFGEIGVGTPPQNFTVIFDTGSSNLWVPSS 409 ++V L N ++ Y E+ +GTPPQ TV+ DTGSS+LWV S Sbjct: 70 ELVELTNQ-NSFYSVELDIGTPPQKVTVLVDTGSSDLWVTGS 110
>YPS1_YEAST (P32329) Aspartic proteinase 3 precursor (EC 3.4.23.41) (Yapsin-1)| Length = 569 Score = 42.7 bits (99), Expect = 7e-04 Identities = 18/30 (60%), Positives = 23/30 (76%) Frame = +2 Query: 320 YFGEIGVGTPPQNFTVIFDTGSSNLWVPSS 409 Y ++ VGTPPQN TV+ DTGSS+LW+ S Sbjct: 83 YSVDLEVGTPPQNVTVLVDTGSSDLWIMGS 112
>PEP2_THUTO (P20140) Pepsin-2 precursor (EC 3.4.23.-) (Fragment)| Length = 72 Score = 42.4 bits (98), Expect = 0.001 Identities = 17/33 (51%), Positives = 22/33 (66%) Frame = +2 Query: 281 DDIVPLDNYLDTQYFGEIGVGTPPQNFTVIFDT 379 D P+ N D Y+G + +GTPPQ+F VIFDT Sbjct: 40 DGTEPMTNDADLSYYGVVSIGTPPQSFKVIFDT 72
>PEPF_ASPFU (P41748) Aspergillopepsin F precursor (EC 3.4.23.18)| (Aspergillopepsin I) Length = 395 Score = 42.4 bits (98), Expect = 0.001 Identities = 34/96 (35%), Positives = 45/96 (46%), Gaps = 1/96 (1%) Frame = +2 Query: 275 SGDDIVPLDNYLDTQYFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKCYFSIACYLHHXXX 454 SG + + Y D++Y + VG N FDTGS++LWV SS+ S + H Sbjct: 72 SGSAVTTPEQY-DSEYLTPVKVGGTTLNLD--FDTGSADLWVFSSE--LSASQSSGHAIY 126 Query: 455 XXXXXXXXXNGETCTISYGSGSIA-GFFSEDSVLVG 559 NG T I YG GS A G +D+V VG Sbjct: 127 KPSANAQKLNGYTWKIQYGDGSSASGDVYKDTVTVG 162
>CARP3_CANAL (P43092) Candidapepsin-3 precursor (EC 3.4.23.24) (Aspartate| protease 3) (ACP 3) (Secreted aspartic protease 3) Length = 398 Score = 39.7 bits (91), Expect = 0.006 Identities = 17/31 (54%), Positives = 22/31 (70%) Frame = +2 Query: 320 YFGEIGVGTPPQNFTVIFDTGSSNLWVPSSK 412 Y +I VG+ Q TV+ DTGSS+LWVP S+ Sbjct: 72 YASDITVGSNKQKLTVVIDTGSSDLWVPDSQ 102
>BAR1_YEAST (P12630) Barrierpepsin precursor (EC 3.4.23.35) (Extracellular| "barrier" protein) (BAR proteinase) Length = 587 Score = 38.5 bits (88), Expect = 0.013 Identities = 25/77 (32%), Positives = 37/77 (48%) Frame = +2 Query: 197 LTAAKLARQETKLLRSDDGSRHSLGLSGDDIVPLDNYLDTQYFGEIGVGTPPQNFTVIFD 376 L A A T ++DG+ H L L + + Y + +GTP Q+ TV+FD Sbjct: 11 LILASFAIINTITALTNDGTGHLEFL-------LQHEEEMYYATTLDIGTPSQSLTVLFD 63 Query: 377 TGSSNLWVPSSKCYFSI 427 TGS++ WV S F + Sbjct: 64 TGSADFWVMDSSNPFCL 80
>CARP1_CANAL (P28872) Candidapepsin-1 precursor (EC 3.4.23.24) (Aspartate| protease 1) (ACP 1) (Secreted aspartic protease 1) Length = 391 Score = 38.5 bits (88), Expect = 0.013 Identities = 18/38 (47%), Positives = 24/38 (63%) Frame = +2 Query: 320 YFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKCYFSIAC 433 Y +I +G+ Q F VI DTGSS+LWVP + S+ C Sbjct: 64 YAADITIGSNKQKFNVIVDTGSSDLWVPDA----SVTC 97
>CARP5_CANAL (P43094) Candidapepsin-5 precursor (EC 3.4.23.24) (Aspartate| protease 5) (ACP 5) (Secreted aspartic protease 5) Length = 418 Score = 38.1 bits (87), Expect = 0.017 Identities = 36/114 (31%), Positives = 53/114 (46%), Gaps = 11/114 (9%) Frame = +2 Query: 101 LWILSCALLLGGAC---SDGLLRINLSKKRL----DKETLTAAK----LARQETKLLRSD 247 L +L+ ALL+ A S G + ++ + KR D T+ A + L ++ + Sbjct: 7 LSVLAFALLIDAAPVKRSPGFVTLDFNVKRSLVDPDDPTVEAKRSPLFLEFTPSEFPVDE 66 Query: 248 DGSRHSLGLSGDDIVPLDNYLDTQYFGEIGVGTPPQNFTVIFDTGSSNLWVPSS 409 G + G V L N T Y +I VG+ Q VI DTGSS+LW+P S Sbjct: 67 TGRDGDVDKRGPVAVTLHNEAIT-YTADITVGSDNQKLNVIVDTGSSDLWIPDS 119
>PENP_PENJA (P00798) Penicillopepsin (EC 3.4.23.20) (Peptidase A)| Length = 323 Score = 38.1 bits (87), Expect = 0.017 Identities = 29/84 (34%), Positives = 39/84 (46%), Gaps = 1/84 (1%) Frame = +2 Query: 311 DTQYFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKCYFSIACYLHHXXXXXXXXXXXXNGE 490 D +Y + +G N FDTGS++LWV S++ + H +G Sbjct: 14 DEEYITPVTIGGTTLNLN--FDTGSADLWVFSTE--LPASQQSGHSVYNPSATGKELSGY 69 Query: 491 TCTISYGSGSIA-GFFSEDSVLVG 559 T +ISYG GS A G DSV VG Sbjct: 70 TWSISYGDGSSASGNVFTDSVTVG 93
>CARP7_CANAL (P43096) Candidapepsin-7 precursor (EC 3.4.23.24) (Aspartate| protease 7) (ACP 7) (Secreted aspartic protease 7) Length = 588 Score = 37.7 bits (86), Expect = 0.022 Identities = 32/99 (32%), Positives = 44/99 (44%), Gaps = 7/99 (7%) Frame = +2 Query: 275 SGDDIVPLDNYLDTQYFGEIGVGTPPQNFTVIFDTGSSNLWVPS---SKCYF---SIACY 436 +G + LDN T Y + VG+P Q V+ DTGSS+LW S S+C SI C Sbjct: 212 TGAFFLSLDN-TQTLYTATLKVGSPAQEVQVMIDTGSSDLWFISSGNSQCKVNGGSIDCD 270 Query: 437 LHHXXXXXXXXXXXXNGETCTISYGSGSIA-GFFSEDSV 550 + N +ISY G A G +D++ Sbjct: 271 KYGVFDKSKSSSWHDNKTDYSISYYDGDKASGTMGQDNI 309
>NEP1_NEPGR (Q766C3) Aspartic proteinase nepenthesin-1 precursor (EC 3.4.23.-)| (Nepenthesin-I) Length = 437 Score = 37.0 bits (84), Expect = 0.038 Identities = 26/83 (31%), Positives = 35/83 (42%), Gaps = 1/83 (1%) Frame = +2 Query: 170 SKKRLDKETLTAAKLARQETKLLRSDDGSRHSLGLSGDDIVPLDNYL-DTQYFGEIGVGT 346 S K L K L + R +L R + L+G V Y D +Y + +GT Sbjct: 50 SGKNLTKFQLLERAIERGSRRLQRLE------AMLNGPSGVETSVYAGDGEYLMNLSIGT 103 Query: 347 PPQNFTVIFDTGSSNLWVPSSKC 415 P Q F+ I DTGS +W C Sbjct: 104 PAQPFSAIMDTGSDLIWTQCQPC 126
>BACE1_MOUSE (P56818) Beta-secretase 1 precursor (EC 3.4.23.46) (Beta-site APP| cleaving enzyme 1) (Beta-site amyloid precursor protein cleaving enzyme 1) (Aspartyl protease 2) (Asp 2) (ASP2) (Membrane-associated aspartic protease 2) (Memapsin-2) Length = 501 Score = 36.6 bits (83), Expect = 0.050 Identities = 21/60 (35%), Positives = 29/60 (48%), Gaps = 3/60 (5%) Frame = +2 Query: 230 KLLRSDDGSRHSLGLSGDDIVPLDNYLDTQ---YFGEIGVGTPPQNFTVIFDTGSSNLWV 400 +L R D G G + +DN Y+ E+ VG+PPQ ++ DTGSSN V Sbjct: 42 RLPRETDEESEEPGRRGSFVEMVDNLRGKSGQGYYVEMTVGSPPQTLNILVDTGSSNFAV 101
>BACE1_RAT (P56819) Beta-secretase 1 precursor (EC 3.4.23.46) (Beta-site APP| cleaving enzyme 1) (Beta-site amyloid precursor protein cleaving enzyme 1) (Aspartyl protease 2) (Asp 2) (ASP2) (Membrane-associated aspartic protease 2) (Memapsin-2) Length = 501 Score = 36.2 bits (82), Expect = 0.065 Identities = 21/60 (35%), Positives = 29/60 (48%), Gaps = 3/60 (5%) Frame = +2 Query: 230 KLLRSDDGSRHSLGLSGDDIVPLDNYLDTQ---YFGEIGVGTPPQNFTVIFDTGSSNLWV 400 +L R D G G + +DN Y+ E+ VG+PPQ ++ DTGSSN V Sbjct: 42 RLPRETDEEPEEPGRRGSFVEMVDNLRGKSGQGYYVEMTVGSPPQTLNILVDTGSSNFAV 101
>BACE1_HUMAN (P56817) Beta-secretase 1 precursor (EC 3.4.23.46) (Beta-site APP| cleaving enzyme 1) (Beta-site amyloid precursor protein cleaving enzyme 1) (Aspartyl protease 2) (Asp 2) (ASP2) (Membrane-associated aspartic protease 2) (Memapsin-2) Length = 501 Score = 36.2 bits (82), Expect = 0.065 Identities = 21/60 (35%), Positives = 29/60 (48%), Gaps = 3/60 (5%) Frame = +2 Query: 230 KLLRSDDGSRHSLGLSGDDIVPLDNYLDTQ---YFGEIGVGTPPQNFTVIFDTGSSNLWV 400 +L R D G G + +DN Y+ E+ VG+PPQ ++ DTGSSN V Sbjct: 42 RLPRETDEEPEEPGRRGSFVEMVDNLRGKSGQGYYVEMTVGSPPQTLNILVDTGSSNFAV 101
>NEP2_NEPGR (Q766C2) Aspartic proteinase nepenthesin-2 precursor (EC 3.4.23.-)| (Nepenthesin-II) Length = 438 Score = 36.2 bits (82), Expect = 0.065 Identities = 13/35 (37%), Positives = 19/35 (54%) Frame = +2 Query: 311 DTQYFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKC 415 D +Y + +GTP +F+ I DTGS +W C Sbjct: 93 DGEYLMNVAIGTPDSSFSAIMDTGSDLIWTQCEPC 127
>CARP2_CANAL (P28871) Candidapepsin-2 precursor (EC 3.4.23.24) (Aspartate| protease 2) (ACP 2) (Secreted aspartic protease 2) Length = 398 Score = 35.4 bits (80), Expect = 0.11 Identities = 16/28 (57%), Positives = 19/28 (67%) Frame = +2 Query: 320 YFGEIGVGTPPQNFTVIFDTGSSNLWVP 403 Y +I VG+ Q VI DTGSS+LWVP Sbjct: 70 YAADITVGSNNQKLNVIVDTGSSDLWVP 97
>PEPA_ASPAW (P17946) Aspergillopepsin A precursor (EC 3.4.23.18)| Length = 394 Score = 35.4 bits (80), Expect = 0.11 Identities = 29/84 (34%), Positives = 37/84 (44%), Gaps = 1/84 (1%) Frame = +2 Query: 311 DTQYFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKCYFSIACYLHHXXXXXXXXXXXXNGE 490 D +Y + VG + FDTGS++LWV S + S H +G Sbjct: 82 DEEYLTPVTVGKSTLHLD--FDTGSADLWVFSDELPSSE--QTGHDLYTPSSSATKLSGY 137 Query: 491 TCTISYGSGSIA-GFFSEDSVLVG 559 T ISYG GS A G D+V VG Sbjct: 138 TWDISYGDGSSASGDVYRDTVTVG 161
>CHYM_FELCA (P09873) Chymosin precursor (EC 3.4.23.4) (Fragment)| Length = 54 Score = 34.7 bits (78), Expect = 0.19 Identities = 12/21 (57%), Positives = 19/21 (90%) Frame = +2 Query: 293 PLDNYLDTQYFGEIGVGTPPQ 355 PL ++LD++YFG+I +GTPP+ Sbjct: 34 PLADFLDSEYFGKIYIGTPPZ 54
>PEPA_ASPOR (Q06902) Aspergillopepsin A precursor (EC 3.4.23.18)| (Aspergillopepsin O) Length = 404 Score = 34.3 bits (77), Expect = 0.25 Identities = 28/84 (33%), Positives = 37/84 (44%), Gaps = 1/84 (1%) Frame = +2 Query: 311 DTQYFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKCYFSIACYLHHXXXXXXXXXXXXNGE 490 D +Y + +G N FDTGS++LWV S + S H G Sbjct: 92 DIEYLTPVNIGGTTLNLD--FDTGSADLWVFSEELPKSE--QTGHDVYKPSGNASKIAGA 147 Query: 491 TCTISYGSGSIA-GFFSEDSVLVG 559 + ISYG GS A G +D+V VG Sbjct: 148 SWDISYGDGSSASGDVYQDTVTVG 171
>PEPB_PIG (Q10735) Pepsin B precursor (EC 3.4.23.2) (Parapepsin I) (Fragment)| Length = 67 Score = 33.9 bits (76), Expect = 0.32 Identities = 13/19 (68%), Positives = 15/19 (78%) Frame = +2 Query: 293 PLDNYLDTQYFGEIGVGTP 349 P NYLD+ YFGEI +GTP Sbjct: 49 PFTNYLDSFYFGEISIGTP 67
>NEP1_NEPDI (P69476) Aspartic proteinase nepenthesin-1 (EC 3.4.23.-)| (Nepenthesin-I) (Fragments) Length = 164 Score = 33.9 bits (76), Expect = 0.32 Identities = 13/29 (44%), Positives = 18/29 (62%) Frame = +2 Query: 311 DTQYFGEIGVGTPPQNFTVIFDTGSSNLW 397 D +Y + +GTP Q F+ I DTGS +W Sbjct: 14 DGEYLMXLSIGTPAQPFSAIMDTGSDLIW 42
>PEPA_ASPSA (Q12567) Aspergillopepsin A precursor (EC 3.4.23.18)| (Aspergillopepsin I) Length = 394 Score = 33.9 bits (76), Expect = 0.32 Identities = 28/84 (33%), Positives = 37/84 (44%), Gaps = 1/84 (1%) Frame = +2 Query: 311 DTQYFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKCYFSIACYLHHXXXXXXXXXXXXNGE 490 D +Y + VG + FDTGS++LWV S + S H +G Sbjct: 82 DEEYLTPVTVGKSTLHLD--FDTGSADLWVFSDELPSSE--QTGHDLYTPSSSATKLSGY 137 Query: 491 TCTISYGSGSIA-GFFSEDSVLVG 559 + ISYG GS A G D+V VG Sbjct: 138 SWDISYGDGSSASGDVYRDTVTVG 161
>CARP8_CANAL (O42778) Candidapepsin-8 precursor (EC 3.4.23.24) (Aspartate| protease 8) (ACP 8) (Secreted aspartic protease 8) Length = 405 Score = 33.5 bits (75), Expect = 0.42 Identities = 17/30 (56%), Positives = 19/30 (63%) Frame = +2 Query: 320 YFGEIGVGTPPQNFTVIFDTGSSNLWVPSS 409 Y I VG+ Q TVI DTGSS+LWV S Sbjct: 89 YAATITVGSNKQQQTVIVDTGSSDLWVVDS 118
>CARP_CANTR (Q00663) Candidapepsin precursor (EC 3.4.23.24) (Aspartate| protease) (ACP) Length = 394 Score = 33.5 bits (75), Expect = 0.42 Identities = 15/27 (55%), Positives = 19/27 (70%) Frame = +2 Query: 320 YFGEIGVGTPPQNFTVIFDTGSSNLWV 400 Y +I VG+ Q TV+ DTGSS+LWV Sbjct: 74 YAADIVVGSNQQKQTVVIDTGSSDLWV 100
>ASP2_BLAGE (P54958) Aspartic protease Bla g 2 precursor (EC 3.4.23.-)| (Allergen Bla g II) Length = 352 Score = 32.7 bits (73), Expect = 0.72 Identities = 22/84 (26%), Positives = 36/84 (42%) Frame = +2 Query: 305 YLDTQYFGEIGVGTPPQNFTVIFDTGSSNLWVPSSKCYFSIACYLHHXXXXXXXXXXXXN 484 +++TQY G +G QNF +FD+ S N+ V S +C + + Sbjct: 34 FINTQYAGITKIGN--QNFLTVFDSTSCNVVVASQECVGGACVCPNLQKYEKLKPKYISD 91 Query: 485 GETCTISYGSGSIAGFFSEDSVLV 556 G + +GS G EDS+ + Sbjct: 92 GNVQVKFFDTGSAVGRGIEDSLTI 115
>PEPA_ASPNG (P55325) Aspergillopepsin A precursor (EC 3.4.23.18)| Length = 394 Score = 32.3 bits (72), Expect = 0.94 Identities = 28/89 (31%), Positives = 38/89 (42%), Gaps = 6/89 (6%) Frame = +2 Query: 311 DTQYFGEIGVGTPPQNFTVIFDTGSSNLW-----VPSSKCYFSIACYLHHXXXXXXXXXX 475 D +Y + VG + FDTGS++LW +PSS+ H Sbjct: 82 DEEYLTPVTVGKSTLHLD--FDTGSADLWGFSDELPSSE-------QTGHDLYTPSSSAT 132 Query: 476 XXNGETCTISYGSGSIA-GFFSEDSVLVG 559 +G + ISYG GS A G D+V VG Sbjct: 133 KLSGYSWDISYGDGSSASGDVYRDTVTVG 161
>IRS2_HUMAN (Q9Y4H2) Insulin receptor substrate 2 (IRS-2)| Length = 1338 Score = 30.0 bits (66), Expect = 4.6 Identities = 18/74 (24%), Positives = 34/74 (45%) Frame = +2 Query: 206 AKLARQETKLLRSDDGSRHSLGLSGDDIVPLDNYLDTQYFGEIGVGTPPQNFTVIFDTGS 385 A+ + +++ +R GS+ S+ + ++P +YL+ + GTPP F+ G Sbjct: 733 AESSPEDSGYMRMWCGSKLSMEHADGKLLPNGDYLNVSPSDAVTTGTPPDFFSAALHPGG 792 Query: 386 SNLWVPSSKCYFSI 427 L CY S+ Sbjct: 793 EPLRGVPGCCYSSL 806
>VG26_BPMD2 (O64220) Minor tail protein Gp26| Length = 836 Score = 30.0 bits (66), Expect = 4.6 Identities = 21/84 (25%), Positives = 34/84 (40%) Frame = +1 Query: 202 SRKIGEAGDKIAEV*RWISPLSRPVR*RHSSPGQLPRHPVLWRDRCRHAAAELHSHI*HG 381 SR +G D + V W+ S V+ GQLP W D E ++ G Sbjct: 541 SRLVGVLADCVGAVAEWVGSWSSGVQQVSDFVGQLPGKIKSWFDDAGSWLIEAGKNVVQG 600 Query: 382 ELKPVGSIIEMLLFDSMLLAPQIQ 453 + +GS+I + + LA ++ Sbjct: 601 LINGIGSMISSAVSKAKELASSVK 624 Database: uniprot_sprot.fasta Posted date: May 25, 2006 5:36 PM Number of letters in database: 80,573,946 Number of sequences in database: 219,361 Lambda K H 0.318 0.135 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 80,997,425 Number of Sequences: 219361 Number of extensions: 1684597 Number of successful extensions: 4714 Number of sequences better than 10.0: 130 Number of HSP's better than 10.0 without gapping: 4448 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 4623 length of database: 80,573,946 effective HSP length: 106 effective length of database: 57,321,680 effective search space used: 4585734400 frameshift window, decay const: 50, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
