ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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| Clone Name | basd2k16 |
|---|---|
| Clone Library Name | barley_pub |
>NEK4_MOUSE (Q9Z1J2) Serine/threonine-protein kinase Nek4 (EC 2.7.11.1)| (NimA-related protein kinase 4) (Serine/threonine-protein kinase 2) Length = 792 Score = 79.0 bits (193), Expect = 9e-15 Identities = 36/96 (37%), Positives = 58/96 (60%) Frame = +2 Query: 293 PMEQYEVVEQIGRGAYGTAYLVHHKAERKRYVMKKIRLTKQNDKFQRTAYQEMSLMASLS 472 P Y + +GRG+YG LV H+ + K+YV+KK+ L + + +R A QE L++ L Sbjct: 2 PQAAYCYMRVVGRGSYGEVTLVKHRRDGKQYVIKKLNLRNASSRERRAAEQEAQLLSQLK 61 Query: 473 NPYIVEYKDGWVDEGTSVCIVTSYCEGGDMAQRIKK 580 +P IV YK+ W + IV +CEGGD+ +++K+ Sbjct: 62 HPNIVTYKESWEGGDGLLYIVMGFCEGGDLYRKLKE 97
>NEK4_HUMAN (P51957) Serine/threonine-protein kinase Nek4 (EC 2.7.11.1)| (NimA-related protein kinase 4) (Serine/threonine-protein kinase 2) (Serine/threonine-protein kinase NRK2) Length = 841 Score = 78.6 bits (192), Expect = 1e-14 Identities = 35/96 (36%), Positives = 59/96 (61%) Frame = +2 Query: 293 PMEQYEVVEQIGRGAYGTAYLVHHKAERKRYVMKKIRLTKQNDKFQRTAYQEMSLMASLS 472 P+ Y + +G+G+YG LV H+ + K+YV+KK+ L + + +R A QE L++ L Sbjct: 2 PLAAYCYLRVVGKGSYGEVTLVKHRRDGKQYVIKKLNLRNASSRERRAAEQEAQLLSQLK 61 Query: 473 NPYIVEYKDGWVDEGTSVCIVTSYCEGGDMAQRIKK 580 +P IV YK+ W + IV +CEGGD+ +++K+ Sbjct: 62 HPNIVTYKESWEGGDGLLYIVMGFCEGGDLYRKLKE 97
>NEK1_MOUSE (P51954) Serine/threonine-protein kinase Nek1 (EC 2.7.11.1)| (NimA-related protein kinase 1) Length = 1203 Score = 77.4 bits (189), Expect = 3e-14 Identities = 35/93 (37%), Positives = 67/93 (72%) Frame = +2 Query: 296 MEQYEVVEQIGRGAYGTAYLVHHKAERKRYVMKKIRLTKQNDKFQRTAYQEMSLMASLSN 475 ME+Y +++IG G++G A LV + + YV+K+I +++ +DK ++ + +E++++A++ + Sbjct: 1 MEKYVRLQKIGEGSFGKAVLVKSTEDGRHYVIKEINISRMSDKERQESRREVAVLANMKH 60 Query: 476 PYIVEYKDGWVDEGTSVCIVTSYCEGGDMAQRI 574 P IV+YK+ + + G S+ IV YCEGGD+ +RI Sbjct: 61 PNIVQYKESFEENG-SLYIVMDYCEGGDLFKRI 92
>NEK1_HUMAN (Q96PY6) Serine/threonine-protein kinase Nek1 (EC 2.7.11.1)| (NimA-related protein kinase 1) (NY-REN-55 antigen) Length = 1258 Score = 73.9 bits (180), Expect = 3e-13 Identities = 33/93 (35%), Positives = 66/93 (70%) Frame = +2 Query: 296 MEQYEVVEQIGRGAYGTAYLVHHKAERKRYVMKKIRLTKQNDKFQRTAYQEMSLMASLSN 475 ME+Y +++IG G++G A LV + ++YV+K+I +++ + K + + +E++++A++ + Sbjct: 1 MEKYVRLQKIGEGSFGKAILVKSTEDGRQYVIKEINISRMSSKEREESRREVAVLANMKH 60 Query: 476 PYIVEYKDGWVDEGTSVCIVTSYCEGGDMAQRI 574 P IV+Y++ + + G S+ IV YCEGGD+ +RI Sbjct: 61 PNIVQYRESFEENG-SLYIVMDYCEGGDLFKRI 92
>NEK3_HUMAN (P51956) Serine/threonine-protein kinase Nek3 (EC 2.7.11.1)| (NimA-related protein kinase 3) (HSPK 36) Length = 506 Score = 72.0 bits (175), Expect = 1e-12 Identities = 37/95 (38%), Positives = 59/95 (62%) Frame = +2 Query: 296 MEQYEVVEQIGRGAYGTAYLVHHKAERKRYVMKKIRLTKQNDKFQRTAYQEMSLMASLSN 475 M+ Y V+ IG G++G A LV H++ + + MK+IRL K Q + +E L+A + + Sbjct: 1 MDDYMVLRMIGEGSFGRALLVQHESSNQMFAMKEIRLPKSFSNTQNSR-KEAVLLAKMKH 59 Query: 476 PYIVEYKDGWVDEGTSVCIVTSYCEGGDMAQRIKK 580 P IV +K+ + EG + IV YC+GGD+ Q+IK+ Sbjct: 60 PNIVAFKESFEAEG-HLYIVMEYCDGGDLMQKIKQ 93
>NEK3_MOUSE (Q9R0A5) Serine/threonine-protein kinase Nek3 (EC 2.7.11.1)| (NimA-related protein kinase 3) Length = 511 Score = 69.7 bits (169), Expect = 6e-12 Identities = 37/95 (38%), Positives = 61/95 (64%) Frame = +2 Query: 296 MEQYEVVEQIGRGAYGTAYLVHHKAERKRYVMKKIRLTKQNDKFQRTAYQEMSLMASLSN 475 M+ Y V+ IG+G++G A LV ++ + + MK+IRL K + +T+ +E L+A + + Sbjct: 1 MDNYTVLRVIGQGSFGRALLVLQESSNQTFAMKEIRLLKSD---TQTSRKEAVLLAKMKH 57 Query: 476 PYIVEYKDGWVDEGTSVCIVTSYCEGGDMAQRIKK 580 P IV +K+ + EG + IV YC+GGD+ QRIK+ Sbjct: 58 PNIVAFKESFEAEG-YLYIVMEYCDGGDLMQRIKQ 91
>NEK2_MOUSE (O35942) Serine/threonine-protein kinase Nek2 (EC 2.7.11.1)| (NimA-related protein kinase 2) Length = 443 Score = 64.7 bits (156), Expect = 2e-10 Identities = 34/96 (35%), Positives = 53/96 (55%), Gaps = 1/96 (1%) Frame = +2 Query: 296 MEQYEVVEQIGRGAYGTAYLVHHKAERKRYVMKKIRLTKQNDKFQRTAYQEMSLMASLSN 475 +E YEV+ IG G+YG + K++ K V K++ + ++ E++L+ L + Sbjct: 5 VEDYEVLHSIGTGSYGRCQKIRRKSDGKILVWKELDYGSMTEVEKQMLVSEVNLLRELKH 64 Query: 476 PYIVEYKDGWVDE-GTSVCIVTSYCEGGDMAQRIKK 580 P IV Y D +D T++ IV YCEGGD+A I K Sbjct: 65 PNIVRYYDRIIDRTNTTLYIVMEYCEGGDLASVISK 100
>NEK2_HUMAN (P51955) Serine/threonine-protein kinase Nek2 (EC 2.7.11.1)| (NimA-related protein kinase 2) (NimA-like protein kinase 1) (HSPK 21) Length = 445 Score = 63.2 bits (152), Expect = 5e-10 Identities = 34/95 (35%), Positives = 52/95 (54%), Gaps = 1/95 (1%) Frame = +2 Query: 299 EQYEVVEQIGRGAYGTAYLVHHKAERKRYVMKKIRLTKQNDKFQRTAYQEMSLMASLSNP 478 E YEV+ IG G+YG + K++ K V K++ + ++ E++L+ L +P Sbjct: 6 EDYEVLYTIGTGSYGRCQKIRRKSDGKILVWKELDYGSMTEAEKQMLVSEVNLLRELKHP 65 Query: 479 YIVEYKDGWVDE-GTSVCIVTSYCEGGDMAQRIKK 580 IV Y D +D T++ IV YCEGGD+A I K Sbjct: 66 NIVRYYDRIIDRTNTTLYIVMEYCEGGDLASVITK 100
>MAST2_HUMAN (Q6P0Q8) Microtubule-associated serine/threonine-protein kinase 2| (EC 2.7.11.1) Length = 1798 Score = 62.0 bits (149), Expect = 1e-09 Identities = 36/97 (37%), Positives = 55/97 (56%), Gaps = 4/97 (4%) Frame = +2 Query: 299 EQYEVVEQIGRGAYGTAYLVHHKAERKRYVMKKIRLTKQN----DKFQRTAYQEMSLMAS 466 E +E ++ I GAYG +LV HK+ R+R+ MKKI KQN ++ Q+ A+ E ++ Sbjct: 510 EDFETIKLISNGAYGAVFLVRHKSTRQRFAMKKI--NKQNLILRNQIQQ-AFVERDILTF 566 Query: 467 LSNPYIVEYKDGWVDEGTSVCIVTSYCEGGDMAQRIK 577 NP++V + D +C+V Y EGGD A +K Sbjct: 567 AENPFVVSMFCSF-DTKRHLCMVMEYVEGGDCATLLK 602
>MAST1_MOUSE (Q9R1L5) Microtubule-associated serine/threonine-protein kinase 1| (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase) Length = 1566 Score = 61.6 bits (148), Expect = 2e-09 Identities = 41/125 (32%), Positives = 67/125 (53%), Gaps = 6/125 (4%) Frame = +2 Query: 221 SNSAPQDEHARARAKEQELGKARNPMEQ--YEVVEQIGRGAYGTAYLVHHKAERKRYVMK 394 SN+ QD+ + R+ KA+ P + ++ ++ I GAYG YLV H+ R+R+ MK Sbjct: 348 SNTPEQDDTSEGRSSTS---KAKKPPGESDFDTIKLISNGAYGAVYLVRHRDTRQRFAMK 404 Query: 395 KIRLTKQN----DKFQRTAYQEMSLMASLSNPYIVEYKDGWVDEGTSVCIVTSYCEGGDM 562 KI KQN ++ Q+ A+ E ++ NP++V + + +C+V Y EGGD Sbjct: 405 KI--NKQNLILRNQIQQ-AFVERDILTFAENPFVVGMFCSF-ETRRHLCMVMEYVEGGDC 460 Query: 563 AQRIK 577 A +K Sbjct: 461 ATLLK 465
>MAST1_RAT (Q810W7) Microtubule-associated serine/threonine-protein kinase 1| (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase) Length = 1570 Score = 61.6 bits (148), Expect = 2e-09 Identities = 41/125 (32%), Positives = 67/125 (53%), Gaps = 6/125 (4%) Frame = +2 Query: 221 SNSAPQDEHARARAKEQELGKARNPMEQ--YEVVEQIGRGAYGTAYLVHHKAERKRYVMK 394 SN+ QD+ + R+ KA+ P + ++ ++ I GAYG YLV H+ R+R+ MK Sbjct: 349 SNTPEQDDTSEGRSSTS---KAKKPPGESDFDTIKLISNGAYGAVYLVRHRDTRQRFAMK 405 Query: 395 KIRLTKQN----DKFQRTAYQEMSLMASLSNPYIVEYKDGWVDEGTSVCIVTSYCEGGDM 562 KI KQN ++ Q+ A+ E ++ NP++V + + +C+V Y EGGD Sbjct: 406 KI--NKQNLILRNQIQQ-AFVERDILTFAENPFVVGMFCSF-ETRRHLCMVMEYVEGGDC 461 Query: 563 AQRIK 577 A +K Sbjct: 462 ATLLK 466
>KIN3_YEAST (P22209) Serine/threonine-protein kinase KIN3 (EC 2.7.11.1)| Length = 435 Score = 61.2 bits (147), Expect = 2e-09 Identities = 36/108 (33%), Positives = 59/108 (54%), Gaps = 1/108 (0%) Frame = +2 Query: 257 RAKEQELGKARNPMEQYEVVEQIGRGAYGTAYLVHHKAERKRYVMKKIRLTKQNDKFQRT 436 R+ +Q+ G P +Y+V+E+IGRG++G+ V H +K V K I+ N K ++ Sbjct: 11 RSPQQQQGHP--PRSEYQVLEEIGRGSFGSVRKVIHIPTKKLLVRKDIKYGHMNSKERQQ 68 Query: 437 AYQEMSLMASLSNPYIVEYKDGWVDEGTSVC-IVTSYCEGGDMAQRIK 577 E S+++ L + IVE+ + DE V + YC GD++Q IK Sbjct: 69 LIAECSILSQLKHENIVEFYNWDFDEQKEVLYLYMEYCSRGDLSQMIK 116
>NEK8_MOUSE (Q91ZR4) Serine/threonine-protein kinase Nek8 (EC 2.7.11.1) (Never| in mitosis A-related kinase 8) (NimA-related protein kinase 8) Length = 698 Score = 61.2 bits (147), Expect = 2e-09 Identities = 29/95 (30%), Positives = 58/95 (61%) Frame = +2 Query: 296 MEQYEVVEQIGRGAYGTAYLVHHKAERKRYVMKKIRLTKQNDKFQRTAYQEMSLMASLSN 475 ME+YE + +GRGA+G +L KA++K ++K+I + + + ++ A E ++ L++ Sbjct: 1 MEKYERIRVVGRGAFGIVHLCLRKADQKLVILKQIPVEQMTKEERQAAQNECQVLKLLNH 60 Query: 476 PYIVEYKDGWVDEGTSVCIVTSYCEGGDMAQRIKK 580 P ++EY + ++ E ++ I Y GG +A+ I+K Sbjct: 61 PNVIEYYENFL-EDKALMIAMEYAPGGTLAEFIQK 94
>MAST1_HUMAN (Q9Y2H9) Microtubule-associated serine/threonine-protein kinase 1| (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase) Length = 1570 Score = 61.2 bits (147), Expect = 2e-09 Identities = 39/123 (31%), Positives = 65/123 (52%), Gaps = 4/123 (3%) Frame = +2 Query: 221 SNSAPQDEHARARAKEQELGKARNPMEQYEVVEQIGRGAYGTAYLVHHKAERKRYVMKKI 400 SN+ QD+ + R+ + + N ++ ++ I GAYG YLV H+ R+R+ MKKI Sbjct: 349 SNTPEQDDLSEGRSSKAKKPPGEN---DFDTIKLISNGAYGAVYLVRHRDTRQRFAMKKI 405 Query: 401 RLTKQN----DKFQRTAYQEMSLMASLSNPYIVEYKDGWVDEGTSVCIVTSYCEGGDMAQ 568 KQN ++ Q+ A+ E ++ NP++V + + +C+V Y EGGD A Sbjct: 406 --NKQNLILRNQIQQ-AFVERDILTFAENPFVVGMFCSF-ETRRHLCMVMEYVEGGDCAT 461 Query: 569 RIK 577 +K Sbjct: 462 LLK 464
>MAST2_MOUSE (Q60592) Microtubule-associated serine/threonine-protein kinase 2| (EC 2.7.11.1) Length = 1734 Score = 60.8 bits (146), Expect = 3e-09 Identities = 39/117 (33%), Positives = 61/117 (52%), Gaps = 4/117 (3%) Frame = +2 Query: 239 DEHARARAKEQELGKARNPMEQYEVVEQIGRGAYGTAYLVHHKAERKRYVMKKIRLTKQN 418 D+ R Q K + E +E ++ I GAYG +LV HK+ R+R+ MKKI KQN Sbjct: 432 DDSVEGRGVSQPSQKTPSE-EDFETIKLISNGAYGAVFLVRHKSTRQRFAMKKI--NKQN 488 Query: 419 ----DKFQRTAYQEMSLMASLSNPYIVEYKDGWVDEGTSVCIVTSYCEGGDMAQRIK 577 ++ Q+ A+ E ++ NP++V + + +C+V Y EGGD A +K Sbjct: 489 LILRNQIQQ-AFVERDILTFAENPFVVSMFCSF-ETKRHLCMVMEYVEGGDCATLLK 543
>NEK8_HUMAN (Q86SG6) Serine/threonine-protein kinase Nek8 (EC 2.7.11.1) (Never| in mitosis A-related kinase 8) (NimA-related protein kinase 8) (NIMA-related kinase 12a) Length = 692 Score = 60.8 bits (146), Expect = 3e-09 Identities = 29/95 (30%), Positives = 58/95 (61%) Frame = +2 Query: 296 MEQYEVVEQIGRGAYGTAYLVHHKAERKRYVMKKIRLTKQNDKFQRTAYQEMSLMASLSN 475 ME+YE + +GRGA+G +L KA++K ++K+I + + + ++ A E ++ L++ Sbjct: 1 MEKYERIRVVGRGAFGIVHLCLRKADQKLVIIKQIPVEQMTKEERQAAQNECQVLKLLNH 60 Query: 476 PYIVEYKDGWVDEGTSVCIVTSYCEGGDMAQRIKK 580 P ++EY + ++ E ++ I Y GG +A+ I+K Sbjct: 61 PNVIEYYENFL-EDKALMIAMEYAPGGTLAEFIQK 94
>ATG1_COLLN (P87248) Serine/threonine-protein kinase ATG1 (EC 2.7.11.1)| (Autophagy-related protein 1) (Colletotrichum lindemuthianum kinase 1) Length = 675 Score = 60.5 bits (145), Expect = 3e-09 Identities = 28/93 (30%), Positives = 53/93 (56%) Frame = +2 Query: 302 QYEVVEQIGRGAYGTAYLVHHKAERKRYVMKKIRLTKQNDKFQRTAYQEMSLMASLSNPY 481 ++ + +IG+G++ Y HHK + +K + + + N+K + Y E+ ++ +L +P+ Sbjct: 24 EFVIGGEIGKGSFAQVYSGHHKNSKAAVAIKSVEMGRLNNKLRENLYGEIQILKTLRHPH 83 Query: 482 IVEYKDGWVDEGTSVCIVTSYCEGGDMAQRIKK 580 IV D V+ T + +V YCE GD++ IKK Sbjct: 84 IVALHD-CVESATHINLVMEYCELGDLSFFIKK 115
>ATG1_MAGGR (Q52EB3) Serine/threonine-protein kinase ATG1 (EC 2.7.11.1)| (Autophagy-related protein 1) Length = 982 Score = 60.5 bits (145), Expect = 3e-09 Identities = 32/110 (29%), Positives = 58/110 (52%) Frame = +2 Query: 251 RARAKEQELGKARNPMEQYEVVEQIGRGAYGTAYLVHHKAERKRYVMKKIRLTKQNDKFQ 430 RAR + +G Q+ + +IG+G++ Y+ HK +K + L + N K + Sbjct: 8 RARPGDDSVG-------QFVIGAEIGKGSFAQVYMGKHKVSGAAVAIKSVELARLNKKLK 60 Query: 431 RTAYQEMSLMASLSNPYIVEYKDGWVDEGTSVCIVTSYCEGGDMAQRIKK 580 Y E++++ +L +P+IV D V+ T + ++ YCE GD++ IKK Sbjct: 61 ENLYGEINILKTLRHPHIVALHD-CVESATHINLMMEYCELGDLSLFIKK 109
>ATG1_NEUCR (Q7RX99) Serine/threonine-protein kinase atg-1 (EC 2.7.11.1)| (Autophagy-related protein 1) Length = 932 Score = 59.7 bits (143), Expect = 6e-09 Identities = 28/92 (30%), Positives = 51/92 (55%) Frame = +2 Query: 305 YEVVEQIGRGAYGTAYLVHHKAERKRYVMKKIRLTKQNDKFQRTAYQEMSLMASLSNPYI 484 + + ++IG+G++ YL HK +K + L + N K + Y E+ ++ +L +P+I Sbjct: 24 FVIDQEIGKGSFAKVYLGRHKVTGALVAVKSVELARLNKKLKENLYGEIQILKTLRHPHI 83 Query: 485 VEYKDGWVDEGTSVCIVTSYCEGGDMAQRIKK 580 V D V+ T + ++ YCE GD++ IKK Sbjct: 84 VALHD-CVESSTHINLIMEYCELGDLSLFIKK 114
>MAST3_HUMAN (O60307) Microtubule-associated serine/threonine-protein kinase 3| (EC 2.7.11.1) Length = 1309 Score = 58.2 bits (139), Expect = 2e-08 Identities = 39/121 (32%), Positives = 62/121 (51%), Gaps = 5/121 (4%) Frame = +2 Query: 230 APQDEHARARAKEQELGKARNPMEQ-YEVVEQIGRGAYGTAYLVHHKAERKRYVMKKIRL 406 AP+ +RA + R P E +E ++ I GAYG YLV H+ R+R+ +KKI Sbjct: 345 APESPESRALVGQSR----RKPCESDFETIKLISNGAYGAVYLVRHRDTRQRFAIKKI-- 398 Query: 407 TKQN----DKFQRTAYQEMSLMASLSNPYIVEYKDGWVDEGTSVCIVTSYCEGGDMAQRI 574 KQN ++ Q+ + E ++ NP++V + + +C+V Y EGGD A + Sbjct: 399 NKQNLILRNQIQQ-VFVERDILTFAENPFVVSMFCSF-ETRRHLCMVMEYVEGGDCATLL 456 Query: 575 K 577 K Sbjct: 457 K 457
>ROCK1_RAT (Q63644) Rho-associated protein kinase 1 (EC 2.7.11.1)| (Rho-associated, coiled-coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK) (p150 RhoA-binding kinase ROK beta) (Liver regeneration-related protein LRRG199) Length = 1369 Score = 57.8 bits (138), Expect = 2e-08 Identities = 35/95 (36%), Positives = 54/95 (56%), Gaps = 3/95 (3%) Frame = +2 Query: 287 RNPMEQYEVVEQIGRGAYGTAYLVHHKAERKRYVMK---KIRLTKQNDKFQRTAYQEMSL 457 R E YEVV+ IGRGA+G LV HK+ RK Y MK K + K++D ++E + Sbjct: 70 RMKAEDYEVVKVIGRGAFGEVQLVRHKSTRKVYAMKLLSKFEMIKRSD--SAFFWEERDI 127 Query: 458 MASLSNPYIVEYKDGWVDEGTSVCIVTSYCEGGDM 562 MA ++P++V+ + D+ + +V Y GGD+ Sbjct: 128 MAFANSPWVVQLFYAFQDD-RYLYMVMEYMPGGDL 161
>ROCK1_RABIT (O77819) Rho-associated protein kinase 1 (EC 2.7.11.1)| (Rho-associated, coiled-coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK) (cAMP-dependent protein kinase ROCK-I) (CePKA) (Corneal epithelial Rho-associated-Ser/Thr kinase 1) (HEB Length = 1354 Score = 57.8 bits (138), Expect = 2e-08 Identities = 35/95 (36%), Positives = 54/95 (56%), Gaps = 3/95 (3%) Frame = +2 Query: 287 RNPMEQYEVVEQIGRGAYGTAYLVHHKAERKRYVMK---KIRLTKQNDKFQRTAYQEMSL 457 R E YEVV+ IGRGA+G LV HK+ RK Y MK K + K++D ++E + Sbjct: 70 RMKAEDYEVVKVIGRGAFGEVQLVRHKSTRKVYAMKLLSKFEMIKRSD--SAFFWEERDI 127 Query: 458 MASLSNPYIVEYKDGWVDEGTSVCIVTSYCEGGDM 562 MA ++P++V+ + D+ + +V Y GGD+ Sbjct: 128 MAFANSPWVVQLFYAFQDD-RYLYMVMEYMPGGDL 161
>ROCK1_MOUSE (P70335) Rho-associated protein kinase 1 (EC 2.7.11.1)| (Rho-associated, coiled-coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK) Length = 1354 Score = 57.8 bits (138), Expect = 2e-08 Identities = 35/95 (36%), Positives = 54/95 (56%), Gaps = 3/95 (3%) Frame = +2 Query: 287 RNPMEQYEVVEQIGRGAYGTAYLVHHKAERKRYVMK---KIRLTKQNDKFQRTAYQEMSL 457 R E YEVV+ IGRGA+G LV HK+ RK Y MK K + K++D ++E + Sbjct: 70 RMKAEDYEVVKVIGRGAFGEVQLVRHKSTRKVYAMKLLSKFEMIKRSD--SAFFWEERDI 127 Query: 458 MASLSNPYIVEYKDGWVDEGTSVCIVTSYCEGGDM 562 MA ++P++V+ + D+ + +V Y GGD+ Sbjct: 128 MAFANSPWVVQLFYAFQDD-RYLYMVMEYMPGGDL 161
>ROCK1_HUMAN (Q13464) Rho-associated protein kinase 1 (EC 2.7.11.1)| (Rho-associated, coiled-coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK) (NY-REN-35 antigen) Length = 1354 Score = 57.8 bits (138), Expect = 2e-08 Identities = 35/95 (36%), Positives = 54/95 (56%), Gaps = 3/95 (3%) Frame = +2 Query: 287 RNPMEQYEVVEQIGRGAYGTAYLVHHKAERKRYVMK---KIRLTKQNDKFQRTAYQEMSL 457 R E YEVV+ IGRGA+G LV HK+ RK Y MK K + K++D ++E + Sbjct: 70 RMKAEDYEVVKVIGRGAFGEVQLVRHKSTRKVYAMKLLSKFEMIKRSD--SAFFWEERDI 127 Query: 458 MASLSNPYIVEYKDGWVDEGTSVCIVTSYCEGGDM 562 MA ++P++V+ + D+ + +V Y GGD+ Sbjct: 128 MAFANSPWVVQLFYAFQDD-RYLYMVMEYMPGGDL 161
>CDC22_MEDSA (Q05006) Cell division control protein 2 homolog 2 (EC 2.7.11.22)| Length = 294 Score = 56.2 bits (134), Expect = 7e-08 Identities = 27/68 (39%), Positives = 41/68 (60%) Frame = +2 Query: 296 MEQYEVVEQIGRGAYGTAYLVHHKAERKRYVMKKIRLTKQNDKFQRTAYQEMSLMASLSN 475 MEQYE VE+IG G YG Y +A + +KKIRL ++++ TA +E+SL+ + + Sbjct: 1 MEQYEKVEKIGEGTYGVVYKARDRATNETIALKKIRLEQEDEGVPSTAIREISLLKEMQH 60 Query: 476 PYIVEYKD 499 IV +D Sbjct: 61 RNIVRLQD 68
>CDC2_PONPY (Q5RCH1) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1) Length = 297 Score = 56.2 bits (134), Expect = 7e-08 Identities = 28/68 (41%), Positives = 38/68 (55%) Frame = +2 Query: 296 MEQYEVVEQIGRGAYGTAYLVHHKAERKRYVMKKIRLTKQNDKFQRTAYQEMSLMASLSN 475 ME Y +E+IG G YG Y HK + MKKIRL + + TA +E+SL+ L + Sbjct: 1 MEDYTKIEKIGEGTYGVVYKGRHKTTGQVVTMKKIRLESEEEGVPSTAIREISLLKELRH 60 Query: 476 PYIVEYKD 499 P IV +D Sbjct: 61 PNIVSLQD 68
>CDC2_HUMAN (P06493) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1) Length = 297 Score = 56.2 bits (134), Expect = 7e-08 Identities = 28/68 (41%), Positives = 38/68 (55%) Frame = +2 Query: 296 MEQYEVVEQIGRGAYGTAYLVHHKAERKRYVMKKIRLTKQNDKFQRTAYQEMSLMASLSN 475 ME Y +E+IG G YG Y HK + MKKIRL + + TA +E+SL+ L + Sbjct: 1 MEDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRH 60 Query: 476 PYIVEYKD 499 P IV +D Sbjct: 61 PNIVSLQD 68
>CDC2_BOVIN (P48734) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1) Length = 297 Score = 56.2 bits (134), Expect = 7e-08 Identities = 28/68 (41%), Positives = 38/68 (55%) Frame = +2 Query: 296 MEQYEVVEQIGRGAYGTAYLVHHKAERKRYVMKKIRLTKQNDKFQRTAYQEMSLMASLSN 475 ME Y +E+IG G YG Y HK + MKKIRL + + TA +E+SL+ L + Sbjct: 1 MEDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRH 60 Query: 476 PYIVEYKD 499 P IV +D Sbjct: 61 PNIVSLQD 68
>NEK11_HUMAN (Q8NG66) Serine/threonine-protein kinase Nek11 (EC 2.7.11.1)| (NimA-related protein kinase 11) (Never in mitosis A-related kinase 11) Length = 645 Score = 56.2 bits (134), Expect = 7e-08 Identities = 30/96 (31%), Positives = 57/96 (59%), Gaps = 3/96 (3%) Frame = +2 Query: 302 QYEVVEQIGRGAYGTAYLVHHKAERKRY---VMKKIRLTKQNDKFQRTAYQEMSLMASLS 472 +Y + +++G G++GT YLV K ++ V+K+I + + N A E L++ L Sbjct: 28 RYVLQQKLGSGSFGTVYLVSDKKAKRGEELKVLKEISVGELNPNETVQANLEAQLLSKLD 87 Query: 473 NPYIVEYKDGWVDEGTSVCIVTSYCEGGDMAQRIKK 580 +P IV++ +V++ + CI+T YCEG D+ +I++ Sbjct: 88 HPAIVKFHASFVEQD-NFCIITEYCEGRDLDDKIQE 122
>ROCK2_RAT (Q62868) Rho-associated protein kinase 2 (EC 2.7.11.1)| (Rho-associated, coiled-coil-containing protein kinase 2) (p164 ROCK-2) (RhoA-binding kinase 2) (p150 ROK-alpha) (ROKalpha) Length = 1379 Score = 56.2 bits (134), Expect = 7e-08 Identities = 33/91 (36%), Positives = 53/91 (58%), Gaps = 3/91 (3%) Frame = +2 Query: 299 EQYEVVEQIGRGAYGTAYLVHHKAERKRYVMK---KIRLTKQNDKFQRTAYQEMSLMASL 469 E Y+VV+ IGRGA+G LV HKA +K Y MK K + K++D ++E +MA Sbjct: 81 EDYDVVKVIGRGAFGEVQLVRHKASQKVYAMKLLSKFEMIKRSD--SAFFWEERDIMAFA 138 Query: 470 SNPYIVEYKDGWVDEGTSVCIVTSYCEGGDM 562 ++P++V+ + D+ + +V Y GGD+ Sbjct: 139 NSPWVVQLFCAFQDD-RYLYMVMEYMPGGDL 168
>ROCK2_MOUSE (P70336) Rho-associated protein kinase 2 (EC 2.7.11.1)| (Rho-associated, coiled-coil-containing protein kinase 2) (p164 ROCK-2) Length = 1388 Score = 56.2 bits (134), Expect = 7e-08 Identities = 33/91 (36%), Positives = 53/91 (58%), Gaps = 3/91 (3%) Frame = +2 Query: 299 EQYEVVEQIGRGAYGTAYLVHHKAERKRYVMK---KIRLTKQNDKFQRTAYQEMSLMASL 469 E Y+VV+ IGRGA+G LV HKA +K Y MK K + K++D ++E +MA Sbjct: 90 EDYDVVKVIGRGAFGEVQLVRHKASQKVYAMKLLSKFEMIKRSD--SAFFWEERDIMAFA 147 Query: 470 SNPYIVEYKDGWVDEGTSVCIVTSYCEGGDM 562 ++P++V+ + D+ + +V Y GGD+ Sbjct: 148 NSPWVVQLFCAFQDD-RYLYMVMEYMPGGDL 177
>ROCK2_HUMAN (O75116) Rho-associated protein kinase 2 (EC 2.7.11.1)| (Rho-associated, coiled-coil-containing protein kinase 2) (p164 ROCK-2) (Rho kinase 2) Length = 1388 Score = 56.2 bits (134), Expect = 7e-08 Identities = 33/91 (36%), Positives = 53/91 (58%), Gaps = 3/91 (3%) Frame = +2 Query: 299 EQYEVVEQIGRGAYGTAYLVHHKAERKRYVMK---KIRLTKQNDKFQRTAYQEMSLMASL 469 E Y+VV+ IGRGA+G LV HKA +K Y MK K + K++D ++E +MA Sbjct: 90 EDYDVVKVIGRGAFGEVQLVRHKASQKVYAMKLLSKFEMIKRSD--SAFFWEERDIMAFA 147 Query: 470 SNPYIVEYKDGWVDEGTSVCIVTSYCEGGDM 562 ++P++V+ + D+ + +V Y GGD+ Sbjct: 148 NSPWVVQLFYAFQDD-RYLYMVMEYMPGGDL 177
>ROCK2_BOVIN (Q28021) Rho-associated protein kinase 2 (EC 2.7.11.1)| (Rho-associated, coiled-coil-containing protein kinase 2) (p164 ROCK-2) Length = 1388 Score = 56.2 bits (134), Expect = 7e-08 Identities = 33/91 (36%), Positives = 53/91 (58%), Gaps = 3/91 (3%) Frame = +2 Query: 299 EQYEVVEQIGRGAYGTAYLVHHKAERKRYVMK---KIRLTKQNDKFQRTAYQEMSLMASL 469 E Y+VV+ IGRGA+G LV HKA +K Y MK K + K++D ++E +MA Sbjct: 90 EDYDVVKVIGRGAFGEVQLVRHKASQKVYAMKLLSKFEMIKRSD--SAFFWEERDIMAFA 147 Query: 470 SNPYIVEYKDGWVDEGTSVCIVTSYCEGGDM 562 ++P++V+ + D+ + +V Y GGD+ Sbjct: 148 NSPWVVQLFCAFQDD-KYLYMVMEYMPGGDL 177
>CDC2_MAIZE (P23111) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34cdc2) Length = 294 Score = 55.8 bits (133), Expect = 8e-08 Identities = 28/68 (41%), Positives = 41/68 (60%) Frame = +2 Query: 296 MEQYEVVEQIGRGAYGTAYLVHHKAERKRYVMKKIRLTKQNDKFQRTAYQEMSLMASLSN 475 MEQYE VE+IG G YG Y KA + +KKIRL ++++ TA +E+SL+ +++ Sbjct: 1 MEQYEKVEKIGEGTYGVVYKALDKATNETIALKKIRLEQEDEGVPSTAIREISLLKEMNH 60 Query: 476 PYIVEYKD 499 IV D Sbjct: 61 GNIVRLHD 68
>NEK11_MACFA (Q8WNU8) Serine/threonine-protein kinase Nek11 (EC 2.7.11.1)| (NimA-related protein kinase 11) (Never in mitosis A-related kinase 11) Length = 637 Score = 55.8 bits (133), Expect = 8e-08 Identities = 30/96 (31%), Positives = 57/96 (59%), Gaps = 3/96 (3%) Frame = +2 Query: 302 QYEVVEQIGRGAYGTAYLVHHKAERKRY---VMKKIRLTKQNDKFQRTAYQEMSLMASLS 472 +Y + +++G G++GT YLV K ++ V+K+I + + N A E L++ L Sbjct: 28 RYVLQQKLGSGSFGTVYLVSDKKAKRGEELKVLKEISVGELNPNETVQANLEAQLLSKLD 87 Query: 473 NPYIVEYKDGWVDEGTSVCIVTSYCEGGDMAQRIKK 580 +P IV++ +V++ + CI+T YCEG D+ +I++ Sbjct: 88 HPAIVKFHASFVEQD-NFCIITEYCEGRDLDYKIQE 122
>CDC22_ORYSA (P29619) Cell division control protein 2 homolog 2 (EC 2.7.11.22)| Length = 292 Score = 55.8 bits (133), Expect = 8e-08 Identities = 27/68 (39%), Positives = 41/68 (60%) Frame = +2 Query: 296 MEQYEVVEQIGRGAYGTAYLVHHKAERKRYVMKKIRLTKQNDKFQRTAYQEMSLMASLSN 475 MEQYE VE+IG G YG Y H+ + +KKIRL ++++ TA +E+SL+ + + Sbjct: 1 MEQYEKVEKIGEGTYGVVYKGKHRHTNETIALKKIRLEQEDEGVPSTAIREISLLKEMQH 60 Query: 476 PYIVEYKD 499 IV +D Sbjct: 61 RNIVRLQD 68
>CDC22_XENLA (P24033) Cell division control protein 2 homolog 2 (EC 2.7.11.22)| (EC 2.7.11.23) (p34 protein kinase 2) Length = 302 Score = 55.5 bits (132), Expect = 1e-07 Identities = 27/64 (42%), Positives = 38/64 (59%) Frame = +2 Query: 296 MEQYEVVEQIGRGAYGTAYLVHHKAERKRYVMKKIRLTKQNDKFQRTAYQEMSLMASLSN 475 M++Y +E+IG G YG Y HKA + MKKIRL + + TA +E+SL+ L + Sbjct: 1 MDEYTKIEKIGEGTYGVVYKGRHKATGQVVAMKKIRLENEEEGVPSTAIREISLLKELQH 60 Query: 476 PYIV 487 P IV Sbjct: 61 PNIV 64
>CDC21_XENLA (P35567) Cell division control protein 2 homolog 1 (EC 2.7.11.22)| (EC 2.7.11.23) (p34 protein kinase 1) Length = 302 Score = 55.5 bits (132), Expect = 1e-07 Identities = 27/64 (42%), Positives = 38/64 (59%) Frame = +2 Query: 296 MEQYEVVEQIGRGAYGTAYLVHHKAERKRYVMKKIRLTKQNDKFQRTAYQEMSLMASLSN 475 M++Y +E+IG G YG Y HKA + MKKIRL + + TA +E+SL+ L + Sbjct: 1 MDEYTKIEKIGEGTYGVVYKGRHKATGQVVAMKKIRLENEEEGVPSTAIREISLLKELQH 60 Query: 476 PYIV 487 P IV Sbjct: 61 PNIV 64
>CDC2A_ARATH (P24100) Cell division control protein 2 homolog A (EC 2.7.11.22)| (EC 2.7.11.23) Length = 294 Score = 55.5 bits (132), Expect = 1e-07 Identities = 26/68 (38%), Positives = 41/68 (60%) Frame = +2 Query: 296 MEQYEVVEQIGRGAYGTAYLVHHKAERKRYVMKKIRLTKQNDKFQRTAYQEMSLMASLSN 475 M+QYE VE+IG G YG Y K + +KKIRL ++++ TA +E+SL+ + + Sbjct: 1 MDQYEKVEKIGEGTYGVVYKARDKVTNETIALKKIRLEQEDEGVPSTAIREISLLKEMQH 60 Query: 476 PYIVEYKD 499 IV+ +D Sbjct: 61 SNIVKLQD 68
>PAK2_RABIT (Q29502) Serine/threonine-protein kinase PAK 2 (EC 2.7.11.1)| (p21-activated kinase 2) (PAK-2) (Gamma-PAK) (p21-activated protein kinase I) (PAKI) Length = 524 Score = 55.5 bits (132), Expect = 1e-07 Identities = 46/177 (25%), Positives = 74/177 (41%), Gaps = 21/177 (11%) Frame = +2 Query: 95 HTRAAAVHARSPLRDHHHQRRALPVSSP--EHHRIIYTRPAATASNSAPQDEHARARAKE 268 +T+ + A D + A PV +P +H + IYTR + D H + AK Sbjct: 158 NTKVSETSAVVTEEDDDDEEAAPPVIAPRPDHTKSIYTRSVIDPIPAPVGDSHVDSGAKS 217 Query: 269 QELGKAR-------------------NPMEQYEVVEQIGRGAYGTAYLVHHKAERKRYVM 391 + K + +P ++Y E+IG+GA GT + A + + Sbjct: 218 SDKQKKKTKMTDEEIMEKLRTIVSIGDPKKKYTRYEKIGQGASGTVFTATDVALGQEVAI 277 Query: 392 KKIRLTKQNDKFQRTAYQEMSLMASLSNPYIVEYKDGWVDEGTSVCIVTSYCEGGDM 562 K+I L KQ K E+ +M L NP IV + D ++ G + +V Y GG + Sbjct: 278 KQINLQKQPKK--ELIINEILVMKELKNPNIVNFLDSYL-VGDELFVVMEYLAGGSL 331
>CDC2_ORYLU (Q9DG98) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1) Length = 303 Score = 55.5 bits (132), Expect = 1e-07 Identities = 28/73 (38%), Positives = 40/73 (54%) Frame = +2 Query: 296 MEQYEVVEQIGRGAYGTAYLVHHKAERKRYVMKKIRLTKQNDKFQRTAYQEMSLMASLSN 475 ME Y +E+IG G YG Y HK+ + MKKIRL + + TA +E+SL+ L + Sbjct: 1 MEDYVKIEKIGEGTYGVVYKGRHKSTGQVVAMKKIRLESEEEGVPSTAVREVSLLQELKH 60 Query: 476 PYIVEYKDGWVDE 514 P +V D + E Sbjct: 61 PNVVRLLDVLMQE 73
>CDC2_ORYLA (Q9DGD3) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1) Length = 303 Score = 55.5 bits (132), Expect = 1e-07 Identities = 28/73 (38%), Positives = 40/73 (54%) Frame = +2 Query: 296 MEQYEVVEQIGRGAYGTAYLVHHKAERKRYVMKKIRLTKQNDKFQRTAYQEMSLMASLSN 475 ME Y +E+IG G YG Y HK+ + MKKIRL + + TA +E+SL+ L + Sbjct: 1 MEDYVKIEKIGEGTYGVVYKGRHKSTGQVVAMKKIRLESEEEGVPSTAVREVSLLQELKH 60 Query: 476 PYIVEYKDGWVDE 514 P +V D + E Sbjct: 61 PNVVRLLDVLMQE 73
>CDC2_ORYJA (Q9DGA2) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1) Length = 303 Score = 55.5 bits (132), Expect = 1e-07 Identities = 28/73 (38%), Positives = 40/73 (54%) Frame = +2 Query: 296 MEQYEVVEQIGRGAYGTAYLVHHKAERKRYVMKKIRLTKQNDKFQRTAYQEMSLMASLSN 475 ME Y +E+IG G YG Y HK+ + MKKIRL + + TA +E+SL+ L + Sbjct: 1 MEDYVKIEKIGEGTYGVVYKGRHKSTGQVVAMKKIRLESEEEGVPSTAVREVSLLQELKH 60 Query: 476 PYIVEYKDGWVDE 514 P +V D + E Sbjct: 61 PNVVRLLDVLMQE 73
>CDC2_ORYCU (Q9DGA5) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1) Length = 303 Score = 55.5 bits (132), Expect = 1e-07 Identities = 28/73 (38%), Positives = 40/73 (54%) Frame = +2 Query: 296 MEQYEVVEQIGRGAYGTAYLVHHKAERKRYVMKKIRLTKQNDKFQRTAYQEMSLMASLSN 475 ME Y +E+IG G YG Y HK+ + MKKIRL + + TA +E+SL+ L + Sbjct: 1 MEDYVKIEKIGEGTYGVVYKGRHKSTGQVVAMKKIRLESEEEGVPSTAVREVSLLQELKH 60 Query: 476 PYIVEYKDGWVDE 514 P +V D + E Sbjct: 61 PNVVRLLDVLMQE 73
>NEK11_MOUSE (Q8C0Q4) Serine/threonine-protein kinase Nek11 (EC 2.7.11.1)| (NimA-related protein kinase 11) (Never in mitosis A-related kinase 11) Length = 628 Score = 55.5 bits (132), Expect = 1e-07 Identities = 31/96 (32%), Positives = 56/96 (58%), Gaps = 3/96 (3%) Frame = +2 Query: 302 QYEVVEQIGRGAYGTAYLVHHKAER---KRYVMKKIRLTKQNDKFQRTAYQEMSLMASLS 472 +Y + +++G G++GT YLV K + + V+K+I + + N A E L++ L Sbjct: 29 RYVLQQKLGSGSFGTVYLVSDKKAKPGEELKVLKEISVGELNPNETVQANVEAQLLSRLH 88 Query: 473 NPYIVEYKDGWVDEGTSVCIVTSYCEGGDMAQRIKK 580 +P IV + ++++ T CI+T YCEG D+ RI++ Sbjct: 89 HPAIVRFHASFMEQET-FCIITEYCEGRDLDYRIQE 123
>NEK9_HUMAN (Q8TD19) Serine/threonine-protein kinase Nek9 (EC 2.7.11.1)| (NimA-related protein kinase 9) (Never in mitosis A-related kinase 9) (Nercc1 kinase) (NIMA-related kinase 8) (Nek8) Length = 979 Score = 55.1 bits (131), Expect = 1e-07 Identities = 36/116 (31%), Positives = 59/116 (50%) Frame = +2 Query: 227 SAPQDEHARARAKEQELGKARNPMEQYEVVEQIGRGAYGTAYLVHHKAERKRYVMKKIRL 406 SA Q A A EQE Y + +GRGA+G A L + V K++ L Sbjct: 33 SASQGPRAGGGAAEQE-------ELHYIPIRVLGRGAFGEATLYRRTEDDSLVVWKEVDL 85 Query: 407 TKQNDKFQRTAYQEMSLMASLSNPYIVEYKDGWVDEGTSVCIVTSYCEGGDMAQRI 574 T+ ++K +R A E+ ++A L + I+ Y + ++D T++ I YC GG++ +I Sbjct: 86 TRLSEKERRDALNEIVILALLQHDNIIAYYNHFMD-NTTLLIELEYCNGGNLYDKI 140
>NEK8_BRARE (Q90XC2) Serine/threonine-protein kinase Nek8 (EC 2.7.11.1)| (NimA-related protein kinase 8) Length = 697 Score = 55.1 bits (131), Expect = 1e-07 Identities = 28/95 (29%), Positives = 52/95 (54%) Frame = +2 Query: 296 MEQYEVVEQIGRGAYGTAYLVHHKAERKRYVMKKIRLTKQNDKFQRTAYQEMSLMASLSN 475 ME+YE + +GRGA+G +L + + ++K+I + + + A E ++ LS+ Sbjct: 1 MEKYEKTKVVGRGAFGIVHLCRRRTDSALVILKEIPVEQMTRDERLAAQNECQVLKLLSH 60 Query: 476 PYIVEYKDGWVDEGTSVCIVTSYCEGGDMAQRIKK 580 P I+EY + ++ E ++ I Y GG +A I+K Sbjct: 61 PNIIEYYENFL-EDKALMIAMEYAPGGTLADYIQK 94
>CDC2_VIGAC (Q41639) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34cdc2) Length = 294 Score = 54.7 bits (130), Expect = 2e-07 Identities = 26/68 (38%), Positives = 40/68 (58%) Frame = +2 Query: 296 MEQYEVVEQIGRGAYGTAYLVHHKAERKRYVMKKIRLTKQNDKFQRTAYQEMSLMASLSN 475 MEQYE VE+IG G YG Y + + +KKIRL ++++ TA +E+SL+ + + Sbjct: 1 MEQYEKVEKIGEGTYGVVYKARDRVTNETIALKKIRLEQEDEGVPSTAIREISLLKEMQH 60 Query: 476 PYIVEYKD 499 IV +D Sbjct: 61 RNIVRLQD 68
>CDC2_CHERU (P93101) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34cdc2) Length = 294 Score = 54.7 bits (130), Expect = 2e-07 Identities = 26/68 (38%), Positives = 40/68 (58%) Frame = +2 Query: 296 MEQYEVVEQIGRGAYGTAYLVHHKAERKRYVMKKIRLTKQNDKFQRTAYQEMSLMASLSN 475 M+QYE VE+IG G YG Y K + +KKIRL ++++ TA +E+SL+ + + Sbjct: 1 MDQYEKVEKIGEGTYGVVYKARDKVTNETIALKKIRLEQEDEGVPSTAIREISLLKEMQH 60 Query: 476 PYIVEYKD 499 IV +D Sbjct: 61 GNIVRLQD 68
>CDC2A_ANTMA (Q38772) Cell division control protein 2 homolog A (EC 2.7.11.22)| (EC 2.7.11.23) Length = 294 Score = 54.7 bits (130), Expect = 2e-07 Identities = 26/68 (38%), Positives = 40/68 (58%) Frame = +2 Query: 296 MEQYEVVEQIGRGAYGTAYLVHHKAERKRYVMKKIRLTKQNDKFQRTAYQEMSLMASLSN 475 MEQYE VE+IG G YG Y + + +KKIRL ++++ TA +E+SL+ + + Sbjct: 1 MEQYEKVEKIGEGTYGVVYKARDRVTNETIALKKIRLEQEDEGVPSTAIREISLLKEMQH 60 Query: 476 PYIVEYKD 499 IV +D Sbjct: 61 GNIVRLQD 68
>ATG1_BOTCI (Q6H9I1) Serine/threonine-protein kinase ATG1 (EC 2.7.11.1)| (Autophagy-related protein 1) (Botryotinia fuckeliana putative kinase exons 1-3) Length = 952 Score = 54.7 bits (130), Expect = 2e-07 Identities = 28/92 (30%), Positives = 50/92 (54%) Frame = +2 Query: 305 YEVVEQIGRGAYGTAYLVHHKAERKRYVMKKIRLTKQNDKFQRTAYQEMSLMASLSNPYI 484 + + EQIG+G++ T Y H +K + L++ N K + Y E+ ++ SL +P+I Sbjct: 23 FTINEQIGKGSFATVYRGTHMPSGNLVAIKSVNLSRLNKKLKDNLYVEIEILKSLYHPHI 82 Query: 485 VEYKDGWVDEGTSVCIVTSYCEGGDMAQRIKK 580 V D + + + ++ YCE GD++ IKK Sbjct: 83 VALID-CRESASHIHLMMEYCELGDLSYFIKK 113
>CDC2_CHICK (P13863) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1) Length = 303 Score = 54.7 bits (130), Expect = 2e-07 Identities = 28/68 (41%), Positives = 38/68 (55%) Frame = +2 Query: 296 MEQYEVVEQIGRGAYGTAYLVHHKAERKRYVMKKIRLTKQNDKFQRTAYQEMSLMASLSN 475 ME Y +E+IG G YG Y HK + MKKIRL + + TA +E+SL+ L + Sbjct: 1 MEDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELHH 60 Query: 476 PYIVEYKD 499 P IV +D Sbjct: 61 PNIVCLQD 68
>CDK10_HUMAN (Q15131) Cell division protein kinase 10 (EC 2.7.11.22)| (Serine/threonine-protein kinase PISSLRE) Length = 360 Score = 54.3 bits (129), Expect = 2e-07 Identities = 30/96 (31%), Positives = 54/96 (56%), Gaps = 1/96 (1%) Frame = +2 Query: 266 EQELGKARNPMEQYEVVEQIGRGAYGTAYLVHHKAERKRYVMKKIRLTKQNDKFQRTAYQ 445 E LG+ R+ ++++E + +IG G YG Y + +KK+R+ K+ D ++ + Sbjct: 27 EHRLGRCRS-VKEFEKLNRIGEGTYGIVYRARDTQTDEIVALKKVRMDKEKDGIPISSLR 85 Query: 446 EMSLMASLSNPYIVEYKDGWV-DEGTSVCIVTSYCE 550 E++L+ L +P IVE K+ V + S+ +V YCE Sbjct: 86 EITLLLRLRHPNIVELKEVVVGNHLESIFLVMGYCE 121
>CDC2_RANDY (Q9W739) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) Length = 302 Score = 54.3 bits (129), Expect = 2e-07 Identities = 27/64 (42%), Positives = 38/64 (59%) Frame = +2 Query: 296 MEQYEVVEQIGRGAYGTAYLVHHKAERKRYVMKKIRLTKQNDKFQRTAYQEMSLMASLSN 475 M++Y +E+IG G YG Y HKA + MKKIRL + + TA +E+SL+ L + Sbjct: 1 MDEYAKIEKIGEGTYGVVYKGVHKATGQIVAMKKIRLENEEEGVPSTAIREISLLKELQH 60 Query: 476 PYIV 487 P IV Sbjct: 61 PNIV 64
>CDC2_RAT (P39951) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1) Length = 297 Score = 54.3 bits (129), Expect = 2e-07 Identities = 27/68 (39%), Positives = 38/68 (55%) Frame = +2 Query: 296 MEQYEVVEQIGRGAYGTAYLVHHKAERKRYVMKKIRLTKQNDKFQRTAYQEMSLMASLSN 475 ME Y +E+IG G YG Y H+ + MKKIRL + + TA +E+SL+ L + Sbjct: 1 MEDYIKIEKIGEGTYGVVYKGRHRTTGQIVAMKKIRLESEEEGVPSTAIREISLLKELRH 60 Query: 476 PYIVEYKD 499 P IV +D Sbjct: 61 PNIVSLQD 68
>CDC2_MOUSE (P11440) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1) Length = 297 Score = 54.3 bits (129), Expect = 2e-07 Identities = 27/68 (39%), Positives = 38/68 (55%) Frame = +2 Query: 296 MEQYEVVEQIGRGAYGTAYLVHHKAERKRYVMKKIRLTKQNDKFQRTAYQEMSLMASLSN 475 ME Y +E+IG G YG Y H+ + MKKIRL + + TA +E+SL+ L + Sbjct: 1 MEDYIKIEKIGEGTYGVVYKGRHRVTGQIVAMKKIRLESEEEGVPSTAIREISLLKELRH 60 Query: 476 PYIVEYKD 499 P IV +D Sbjct: 61 PNIVSLQD 68
>NEK9_MOUSE (Q8K1R7) Serine/threonine-protein kinase Nek9 (EC 2.7.11.1)| (NimA-related protein kinase 9) (Never in mitosis A-related kinase 9) Length = 984 Score = 54.3 bits (129), Expect = 2e-07 Identities = 30/99 (30%), Positives = 53/99 (53%) Frame = +2 Query: 278 GKARNPMEQYEVVEQIGRGAYGTAYLVHHKAERKRYVMKKIRLTKQNDKFQRTAYQEMSL 457 G A Y + +GRGA+G A L + V K++ LT+ ++K +R A E+ + Sbjct: 43 GAAEQEELHYIPIRVLGRGAFGEATLYRRTEDDSLVVWKEVDLTRLSEKERRDALNEIVI 102 Query: 458 MASLSNPYIVEYKDGWVDEGTSVCIVTSYCEGGDMAQRI 574 +A L + I+ Y + ++D T++ I YC GG++ +I Sbjct: 103 LALLQHDNIIAYYNHFMD-NTTLLIELEYCNGGNLYDKI 140
>CDC2_VIGUN (P52389) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34cdc2) Length = 294 Score = 53.9 bits (128), Expect = 3e-07 Identities = 26/68 (38%), Positives = 40/68 (58%) Frame = +2 Query: 296 MEQYEVVEQIGRGAYGTAYLVHHKAERKRYVMKKIRLTKQNDKFQRTAYQEMSLMASLSN 475 MEQYE VE+IG G YG Y + + +KKIRL ++++ TA +E+SL+ + + Sbjct: 1 MEQYEKVEKIGEGTYGVVYKARDRVTDETIALKKIRLEQEDEGVPSTAIREISLLKEMQH 60 Query: 476 PYIVEYKD 499 IV +D Sbjct: 61 RNIVRLQD 68
>CDK2_CARAU (P43450) Cell division protein kinase 2 (EC 2.7.11.22)| Length = 298 Score = 53.9 bits (128), Expect = 3e-07 Identities = 26/68 (38%), Positives = 40/68 (58%) Frame = +2 Query: 296 MEQYEVVEQIGRGAYGTAYLVHHKAERKRYVMKKIRLTKQNDKFQRTAYQEMSLMASLSN 475 ME ++ VE+IG G YG Y +K + +KKIRL + + TA +E+SL+ L++ Sbjct: 1 MESFQKVEKIGEGTYGVVYKAKNKVTGETVALKKIRLDTETEGVPSTAIREISLLKELNH 60 Query: 476 PYIVEYKD 499 P IV+ D Sbjct: 61 PNIVKLHD 68
>PAK2_HUMAN (Q13177) Serine/threonine-protein kinase PAK 2 (EC 2.7.11.1)| (p21-activated kinase 2) (PAK-2) (PAK65) (Gamma-PAK) (S6/H4 kinase) Length = 524 Score = 53.5 bits (127), Expect = 4e-07 Identities = 50/183 (27%), Positives = 75/183 (40%), Gaps = 21/183 (11%) Frame = +2 Query: 77 PLLSHFHTRAAAVHARSPLRDHHHQRRALPVSSP--EHHRIIYTRPAATASNSAPQDEHA 250 P L+ T A AV D + A PV +P +H + IYTR + D H Sbjct: 155 PALNAKGTEAPAVVTEEEDDD---EETAPPVIAPRPDHTKSIYTRSVIDPVPAPVGDSHV 211 Query: 251 RARAKEQELGKAR-------------------NPMEQYEVVEQIGRGAYGTAYLVHHKAE 373 AK + K + +P ++Y E+IG+GA GT + A Sbjct: 212 DGAAKSLDKQKKKPKMTDEEIMEKLRTIVSIGDPKKKYTRYEKIGQGASGTVFTATDVAL 271 Query: 374 RKRYVMKKIRLTKQNDKFQRTAYQEMSLMASLSNPYIVEYKDGWVDEGTSVCIVTSYCEG 553 + +K+I L KQ K E+ +M L NP IV + D ++ G + +V Y G Sbjct: 272 GQEVAIKQINLQKQPKK--ELIINEILVMKELKNPNIVNFLDSYL-VGDELFVVMEYLAG 328 Query: 554 GDM 562 G + Sbjct: 329 GSL 331
>PAK2_RAT (Q64303) Serine/threonine-protein kinase PAK 2 (EC 2.7.11.1)| (p21-activated kinase 2) (PAK-2) (Gamma-PAK) (p62-PAK) Length = 524 Score = 53.1 bits (126), Expect = 6e-07 Identities = 49/177 (27%), Positives = 80/177 (45%), Gaps = 21/177 (11%) Frame = +2 Query: 95 HTRAAAVHARSPLRDHHHQRRALPVSSP--EHHRIIYTR------PA----ATASNSAPQ 238 +T+ + A D + A PV +P +H + IYTR PA + + A Sbjct: 158 NTKGSETSAVVTEEDDDDEDAAPPVIAPRPDHTKSIYTRSVIDPIPAPVGDSNVDSGAKS 217 Query: 239 DEHARARAK---EQELGKAR------NPMEQYEVVEQIGRGAYGTAYLVHHKAERKRYVM 391 + + +AK E+ + K R +P ++Y E+IG+GA GT + A + + Sbjct: 218 SDKQKKKAKMTDEEIMEKLRTIVSIGDPKKKYTRYEKIGQGASGTVFTATDVALGQEVAI 277 Query: 392 KKIRLTKQNDKFQRTAYQEMSLMASLSNPYIVEYKDGWVDEGTSVCIVTSYCEGGDM 562 K+I L KQ K E+ +M L NP IV + D ++ G + +V Y GG + Sbjct: 278 KQINLQKQPKK--ELIINEILVMKELKNPNIVNFLDSYL-VGDELFVVMEYLAGGSL 331
>PAK2_MOUSE (Q8CIN4) Serine/threonine-protein kinase PAK 2 (EC 2.7.11.1)| (p21-activated kinase 2) (PAK-2) Length = 524 Score = 53.1 bits (126), Expect = 6e-07 Identities = 49/177 (27%), Positives = 80/177 (45%), Gaps = 21/177 (11%) Frame = +2 Query: 95 HTRAAAVHARSPLRDHHHQRRALPVSSP--EHHRIIYTR------PA----ATASNSAPQ 238 +T+ + A D + A PV +P +H + IYTR PA + + A Sbjct: 158 NTKGSETSAVVTEEDDDDEDAAPPVIAPRPDHTKSIYTRSVIDPIPAPVGDSNVDSGAKS 217 Query: 239 DEHARARAK---EQELGKAR------NPMEQYEVVEQIGRGAYGTAYLVHHKAERKRYVM 391 + + +AK E+ + K R +P ++Y E+IG+GA GT + A + + Sbjct: 218 SDKQKKKAKMTDEEIMEKLRTIVSIGDPKKKYTRYEKIGQGASGTVFTATDVALGQEVAI 277 Query: 392 KKIRLTKQNDKFQRTAYQEMSLMASLSNPYIVEYKDGWVDEGTSVCIVTSYCEGGDM 562 K+I L KQ K E+ +M L NP IV + D ++ G + +V Y GG + Sbjct: 278 KQINLQKQPKK--ELIINEILVMKELKNPNIVNFLDSYL-VGDELFVVMEYLAGGSL 331
>E2AK2_SCHPO (Q9UTE5) Eukaryotic translation initiation factor 2-alpha kinase 2| (EC 2.7.11.1) (Heme-regulated eukaryotic initiation factor eIF-2-alpha kinase) (Heme-regulated inhibitor 2) Length = 639 Score = 52.8 bits (125), Expect = 7e-07 Identities = 27/85 (31%), Positives = 46/85 (54%), Gaps = 3/85 (3%) Frame = +2 Query: 296 MEQYEVVEQIGRGAYGTAYLVHHKAERKRYVMKKIRLTKQNDKFQRTAYQEMSLMASLSN 475 +E +E +GRG +G+ Y V +K + Y MKKI T Q + + ++E+ +A + + Sbjct: 168 IEDFEEYSLLGRGGFGSVYHVRNKIDGAEYAMKKINSTFQQMSYSK-IFREIKCLAKMDH 226 Query: 476 PYIVEYKDGWVD---EGTSVCIVTS 541 P ++ Y WV+ E T + IV S Sbjct: 227 PNVIRYFSSWVESTTEATQMPIVMS 251
>SAPK5_ORYSA (Q7XKA8) Serine/threonine-protein kinase SAPK5 (EC 2.7.11.1)| (Osmotic stress/abscisic acid-activated protein kinase 5) Length = 370 Score = 52.8 bits (125), Expect = 7e-07 Identities = 31/93 (33%), Positives = 52/93 (55%) Frame = +2 Query: 296 MEQYEVVEQIGRGAYGTAYLVHHKAERKRYVMKKIRLTKQNDKFQRTAYQEMSLMASLSN 475 ME+YE V +IG G +G A L+ +K R+ MK I ++ ++ ++E+ SL + Sbjct: 1 MEKYEPVREIGAGNFGVAKLMRNKETRELVAMKFI---ERGNRIDENVFREIVNHRSLRH 57 Query: 476 PYIVEYKDGWVDEGTSVCIVTSYCEGGDMAQRI 574 P I+ +K+ V G + IV Y GG++ +RI Sbjct: 58 PNIIRFKE-VVVTGRHLAIVMEYAAGGELFERI 89
>CDK2_HUMAN (P24941) Cell division protein kinase 2 (EC 2.7.11.22) (p33 protein| kinase) Length = 298 Score = 52.8 bits (125), Expect = 7e-07 Identities = 26/68 (38%), Positives = 40/68 (58%) Frame = +2 Query: 296 MEQYEVVEQIGRGAYGTAYLVHHKAERKRYVMKKIRLTKQNDKFQRTAYQEMSLMASLSN 475 ME ++ VE+IG G YG Y +K + +KKIRL + + TA +E+SL+ L++ Sbjct: 1 MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNH 60 Query: 476 PYIVEYKD 499 P IV+ D Sbjct: 61 PNIVKLLD 68
>CDK2_MOUSE (P97377) Cell division protein kinase 2 (EC 2.7.11.22)| Length = 346 Score = 52.4 bits (124), Expect = 9e-07 Identities = 26/68 (38%), Positives = 40/68 (58%) Frame = +2 Query: 296 MEQYEVVEQIGRGAYGTAYLVHHKAERKRYVMKKIRLTKQNDKFQRTAYQEMSLMASLSN 475 ME ++ VE+IG G YG Y +K + +KKIRL + + TA +E+SL+ L++ Sbjct: 1 MENFQKVEKIGEGTYGVVYKAKNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNH 60 Query: 476 PYIVEYKD 499 P IV+ D Sbjct: 61 PNIVKLLD 68
>CDC21_ORYSA (P29618) Cell division control protein 2 homolog 1 (EC 2.7.11.22)| Length = 294 Score = 52.4 bits (124), Expect = 9e-07 Identities = 26/68 (38%), Positives = 38/68 (55%) Frame = +2 Query: 296 MEQYEVVEQIGRGAYGTAYLVHHKAERKRYVMKKIRLTKQNDKFQRTAYQEMSLMASLSN 475 MEQYE E+IG G YG Y K + +KKIRL ++++ TA +E+SL+ + + Sbjct: 1 MEQYEKEEKIGEGTYGVVYRARDKVTNETIALKKIRLEQEDEGVPSTAIREISLLKEMHH 60 Query: 476 PYIVEYKD 499 IV D Sbjct: 61 GNIVRLHD 68
>CDK2_RAT (Q63699) Cell division protein kinase 2 (EC 2.7.11.22)| Length = 298 Score = 52.4 bits (124), Expect = 9e-07 Identities = 26/68 (38%), Positives = 40/68 (58%) Frame = +2 Query: 296 MEQYEVVEQIGRGAYGTAYLVHHKAERKRYVMKKIRLTKQNDKFQRTAYQEMSLMASLSN 475 ME ++ VE+IG G YG Y +K + +KKIRL + + TA +E+SL+ L++ Sbjct: 1 MENFQKVEKIGEGTYGVVYKAKNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNH 60 Query: 476 PYIVEYKD 499 P IV+ D Sbjct: 61 PNIVKLLD 68
>CDK2_MESAU (P48963) Cell division protein kinase 2 (EC 2.7.11.22)| Length = 298 Score = 52.4 bits (124), Expect = 9e-07 Identities = 26/68 (38%), Positives = 40/68 (58%) Frame = +2 Query: 296 MEQYEVVEQIGRGAYGTAYLVHHKAERKRYVMKKIRLTKQNDKFQRTAYQEMSLMASLSN 475 ME ++ VE+IG G YG Y +K + +KKIRL + + TA +E+SL+ L++ Sbjct: 1 MENFQKVEKIGEGTYGVVYKAKNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNH 60 Query: 476 PYIVEYKD 499 P IV+ D Sbjct: 61 PNIVKLLD 68
>CDK2_CRIGR (O55076) Cell division protein kinase 2 (EC 2.7.11.22)| Length = 298 Score = 52.4 bits (124), Expect = 9e-07 Identities = 26/68 (38%), Positives = 40/68 (58%) Frame = +2 Query: 296 MEQYEVVEQIGRGAYGTAYLVHHKAERKRYVMKKIRLTKQNDKFQRTAYQEMSLMASLSN 475 ME ++ VE+IG G YG Y +K + +KKIRL + + TA +E+SL+ L++ Sbjct: 1 MENFQKVEKIGEGTYGVVYKAKNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNH 60 Query: 476 PYIVEYKD 499 P IV+ D Sbjct: 61 PNIVKLLD 68
>CDK2_BOVIN (Q5E9Y0) Cell division protein kinase 2 (EC 2.7.11.22)| Length = 298 Score = 52.4 bits (124), Expect = 9e-07 Identities = 26/68 (38%), Positives = 40/68 (58%) Frame = +2 Query: 296 MEQYEVVEQIGRGAYGTAYLVHHKAERKRYVMKKIRLTKQNDKFQRTAYQEMSLMASLSN 475 ME ++ VE+IG G YG Y +K + +KKIRL + + TA +E+SL+ L++ Sbjct: 1 MENFQKVEKIGEGTYGVVYKAKNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNH 60 Query: 476 PYIVEYKD 499 P IV+ D Sbjct: 61 PNIVKLLD 68
>E2AK1_RABIT (P33279) Eukaryotic translation initiation factor 2-alpha kinase 1| (EC 2.7.11.1) (Heme-regulated eukaryotic initiation factor eIF-2-alpha kinase) (Heme-regulated inhibitor) (Heme-controlled repressor) (HCR) (Hemin-sensitive initiation factor Length = 626 Score = 52.0 bits (123), Expect = 1e-06 Identities = 33/123 (26%), Positives = 54/123 (43%) Frame = +2 Query: 143 HHQRRALPVSSPEHHRIIYTRPAATASNSAPQDEHARARAKEQELGKARNPMEQYEVVEQ 322 HH R + R+ R A NS Q +R A E + + N E+ + Sbjct: 122 HHNRAITHLMRSARERV---RQDPCADNSHIQKIRSREVALEAQTSRYLNEFEELSI--- 175 Query: 323 IGRGAYGTAYLVHHKAERKRYVMKKIRLTKQNDKFQRTAYQEMSLMASLSNPYIVEYKDG 502 +G+G YG Y V +K + + Y +KKI + +E+ ++A L +P IV Y Sbjct: 176 LGKGGYGRVYKVRNKLDGQYYAIKKILIKGATKTDCMKVLREVKVLAGLQHPNIVGYHTA 235 Query: 503 WVD 511 W++ Sbjct: 236 WIE 238
>NEK6_RAT (P59895) Serine/threonine-protein kinase Nek6 (EC 2.7.11.1)| (NimA-related protein kinase 6) Length = 313 Score = 52.0 bits (123), Expect = 1e-06 Identities = 27/98 (27%), Positives = 55/98 (56%), Gaps = 1/98 (1%) Frame = +2 Query: 287 RNPMEQYEVVEQIGRGAYGTAYLVHHKAERKRYVMKKIRLTKQND-KFQRTAYQEMSLMA 463 R + +++ ++IGRG + Y +RK +KK+++ + D K ++ +E+ L+ Sbjct: 39 RCSLADFQIEKKIGRGQFSEVYKATCLLDRKTVALKKVQIFEMMDAKARQDCVKEIGLLK 98 Query: 464 SLSNPYIVEYKDGWVDEGTSVCIVTSYCEGGDMAQRIK 577 L++P I++Y D ++ E + IV + GD++Q IK Sbjct: 99 QLNHPNIIKYLDSFI-EDNELNIVLELADAGDLSQMIK 135
>NEK6_MOUSE (Q9ES70) Serine/threonine-protein kinase Nek6 (EC 2.7.11.1)| (NimA-related protein kinase 6) Length = 313 Score = 52.0 bits (123), Expect = 1e-06 Identities = 27/98 (27%), Positives = 55/98 (56%), Gaps = 1/98 (1%) Frame = +2 Query: 287 RNPMEQYEVVEQIGRGAYGTAYLVHHKAERKRYVMKKIRLTKQND-KFQRTAYQEMSLMA 463 R + +++ ++IGRG + Y +RK +KK+++ + D K ++ +E+ L+ Sbjct: 39 RCSLADFQIEKKIGRGQFSEVYKATCLLDRKTVALKKVQIFEMMDAKARQDCVKEIGLLK 98 Query: 464 SLSNPYIVEYKDGWVDEGTSVCIVTSYCEGGDMAQRIK 577 L++P I++Y D ++ E + IV + GD++Q IK Sbjct: 99 QLNHPNIIKYLDSFI-EDNELNIVLELADAGDLSQMIK 135
>NEK6_HUMAN (Q9HC98) Serine/threonine-protein kinase Nek6 (EC 2.7.11.1)| (NimA-related protein kinase 6) (Protein kinase SID6-1512) Length = 313 Score = 52.0 bits (123), Expect = 1e-06 Identities = 27/98 (27%), Positives = 55/98 (56%), Gaps = 1/98 (1%) Frame = +2 Query: 287 RNPMEQYEVVEQIGRGAYGTAYLVHHKAERKRYVMKKIRLTKQND-KFQRTAYQEMSLMA 463 R + +++ ++IGRG + Y +RK +KK+++ + D K ++ +E+ L+ Sbjct: 39 RCSLADFQIEKKIGRGQFSEVYKATCLLDRKTVALKKVQIFEMMDAKARQDCVKEIGLLK 98 Query: 464 SLSNPYIVEYKDGWVDEGTSVCIVTSYCEGGDMAQRIK 577 L++P I++Y D ++ E + IV + GD++Q IK Sbjct: 99 QLNHPNIIKYLDSFI-EDNELNIVLELADAGDLSQMIK 135
>CD2L7_CAEEL (P46551) Putative cell division cycle 2-related protein kinase 7| (EC 2.7.11.22) Length = 730 Score = 52.0 bits (123), Expect = 1e-06 Identities = 32/121 (26%), Positives = 56/121 (46%) Frame = +2 Query: 152 RRALPVSSPEHHRIIYTRPAATASNSAPQDEHARARAKEQELGKARNPMEQYEVVEQIGR 331 +R P+ P + I TRP T HA R + + N + Y +++QIG Sbjct: 266 KRQDPLPMPPDSKRIATRPVITTRRG-----HATNRPSDSDSWYKTN-LTHYTMLDQIGE 319 Query: 332 GAYGTAYLVHHKAERKRYVMKKIRLTKQNDKFQRTAYQEMSLMASLSNPYIVEYKDGWVD 511 G YG Y + ++ +K++RL + + F TA +E+ ++ L + IV D +D Sbjct: 320 GTYGQVYKAVNNLTGEQVALKRVRLENEKEGFPITAIREIKILRQLHHKNIVRLMDIVID 379 Query: 512 E 514 + Sbjct: 380 D 380
>CDPK2_ORYSA (P53683) Calcium-dependent protein kinase, isoform 2 (EC 2.7.11.1)| (CDPK 2) Length = 533 Score = 45.4 bits (106), Expect(2) = 1e-06 Identities = 33/105 (31%), Positives = 55/105 (52%), Gaps = 5/105 (4%) Frame = +2 Query: 275 LGKARNPMEQ-YEVVEQIGRGAYGTAYLVHHKAERKRYVMKKI---RLTKQNDKFQRTAY 442 LGK + + Y + +++GRG +G YL A K+Y K I +L + DK Sbjct: 74 LGKPYDDVRSVYSLGKELGRGQFGVTYLCTEIASGKQYACKSISKRKLVSKADK--EDIR 131 Query: 443 QEMSLMASLSNPY-IVEYKDGWVDEGTSVCIVTSYCEGGDMAQRI 574 +E+ +M LS IVE++ + D+ ++V +V C GG++ RI Sbjct: 132 REIQIMQHLSGQQNIVEFRGAYEDK-SNVHVVMELCAGGELFDRI 175 Score = 25.8 bits (55), Expect(2) = 1e-06 Identities = 11/21 (52%), Positives = 13/21 (61%) Frame = +3 Query: 183 TIESFIRAQPPPPATVRHKTS 245 T S+ QPPPPA VR+ S Sbjct: 32 TTPSYNHPQPPPPAEVRYTPS 52
>CDK2_XENLA (P23437) Cell division protein kinase 2 (EC 2.7.11.22) (CDC2| homolog Eg1 protein kinase) Length = 297 Score = 51.6 bits (122), Expect = 2e-06 Identities = 25/68 (36%), Positives = 40/68 (58%) Frame = +2 Query: 296 MEQYEVVEQIGRGAYGTAYLVHHKAERKRYVMKKIRLTKQNDKFQRTAYQEMSLMASLSN 475 ME ++ VE+IG G YG Y ++ + +KKIRL + + TA +E+SL+ L++ Sbjct: 1 MENFQKVEKIGEGTYGVVYKARNRETGEIVALKKIRLDTETEGVPSTAIREISLLKELNH 60 Query: 476 PYIVEYKD 499 P IV+ D Sbjct: 61 PNIVKLLD 68
>CDC2_SCHPO (P04551) Cell division control protein 2 (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinse) Length = 297 Score = 51.6 bits (122), Expect = 2e-06 Identities = 24/60 (40%), Positives = 36/60 (60%) Frame = +2 Query: 296 MEQYEVVEQIGRGAYGTAYLVHHKAERKRYVMKKIRLTKQNDKFQRTAYQEMSLMASLSN 475 ME Y+ VE+IG G YG Y HK + MKKIRL +++ TA +E+SL+ +++ Sbjct: 1 MENYQKVEKIGEGTYGVVYKARHKLSGRIVAMKKIRLEDESEGVPSTAIREISLLKEVND 60
>E2AK1_RAT (Q63185) Eukaryotic translation initiation factor 2-alpha kinase 1| (EC 2.7.11.1) (Heme-regulated eukaryotic initiation factor eIF-2-alpha kinase) (Heme-regulated inhibitor) (Heme-controlled repressor) (HCR) (Hemin-sensitive initiation factor 2- Length = 620 Score = 51.2 bits (121), Expect = 2e-06 Identities = 32/123 (26%), Positives = 53/123 (43%) Frame = +2 Query: 143 HHQRRALPVSSPEHHRIIYTRPAATASNSAPQDEHARARAKEQELGKARNPMEQYEVVEQ 322 HH R + R+ R NS Q +R A E + + N E+ + Sbjct: 119 HHNRAITHLMRSAKERV---RQDPCQDNSYMQKIRSREIALEAQTSRYLNEFEELAI--- 172 Query: 323 IGRGAYGTAYLVHHKAERKRYVMKKIRLTKQNDKFQRTAYQEMSLMASLSNPYIVEYKDG 502 +G+G YG Y V +K + + Y +KKI + +E+ ++A L +P IV Y Sbjct: 173 LGKGGYGRVYKVRNKLDGQHYAIKKILIKSATKTDCMKVLREVKVLAGLQHPNIVGYHTA 232 Query: 503 WVD 511 W++ Sbjct: 233 WIE 235
>STK3_HUMAN (Q13188) Serine/threonine-protein kinase 3 (EC 2.7.11.1)| (STE20-like kinase MST2) (MST-2) (Mammalian STE20-like protein kinase 2) (Serine/threonine-protein kinase Krs-1) Length = 491 Score = 50.8 bits (120), Expect = 3e-06 Identities = 27/105 (25%), Positives = 54/105 (51%) Frame = +2 Query: 263 KEQELGKARNPMEQYEVVEQIGRGAYGTAYLVHHKAERKRYVMKKIRLTKQNDKFQRTAY 442 K E + P E ++V+E++G G+YG+ + HK + +K++ + + Sbjct: 13 KLSEDSLTKQPEEVFDVLEKLGEGSYGSVFKAIHKESGQVVAIKQVPVESDLQEI----I 68 Query: 443 QEMSLMASLSNPYIVEYKDGWVDEGTSVCIVTSYCEGGDMAQRIK 577 +E+S+M +PY+V+Y + + T + IV YC G ++ I+ Sbjct: 69 KEISIMQQCDSPYVVKYYGSYF-KNTDLWIVMEYCGAGSVSDIIR 112
>CDC2_CARAU (P51958) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1) Length = 302 Score = 50.8 bits (120), Expect = 3e-06 Identities = 26/73 (35%), Positives = 39/73 (53%) Frame = +2 Query: 296 MEQYEVVEQIGRGAYGTAYLVHHKAERKRYVMKKIRLTKQNDKFQRTAYQEMSLMASLSN 475 M+ Y +E+IG G YG Y +K + MKKIRL + + TA +E+SL+ L + Sbjct: 1 MDDYLKIEKIGEGTYGVVYKGRNKTTGQVVAMKKIRLESEEEGVPSTAVREISLLKELQH 60 Query: 476 PYIVEYKDGWVDE 514 P +V D + E Sbjct: 61 PNVVRLLDVLMQE 73
>ATG1_YARLI (Q6C7U0) Serine/threonine-protein kinase ATG1 (EC 2.7.11.1)| (Autophagy-related protein 1) Length = 710 Score = 50.8 bits (120), Expect = 3e-06 Identities = 26/95 (27%), Positives = 48/95 (50%) Frame = +2 Query: 296 MEQYEVVEQIGRGAYGTAYLVHHKAERKRYVMKKIRLTKQNDKFQRTAYQEMSLMASLSN 475 ++ Y + ++GRG++ T Y H A +K + K N K E+S++ + + Sbjct: 4 IKSYTIGNELGRGSFATVYKGEHVASGSPVAIKSVLRAKLNRKLLENLGSEISILKQMKH 63 Query: 476 PYIVEYKDGWVDEGTSVCIVTSYCEGGDMAQRIKK 580 P++VE D + + T +V YC GD++ +KK Sbjct: 64 PHVVELLD-FQETPTHFHLVMEYCSLGDLSFFLKK 97
>E2AK1_MOUSE (Q9Z2R9) Eukaryotic translation initiation factor 2-alpha kinase 1| (EC 2.7.11.1) (Heme-regulated eukaryotic initiation factor eIF-2-alpha kinase) (Heme-regulated inhibitor) (Heme-controlled repressor) (HCR) (Hemin-sensitive initiation factor Length = 619 Score = 50.8 bits (120), Expect = 3e-06 Identities = 32/123 (26%), Positives = 53/123 (43%) Frame = +2 Query: 143 HHQRRALPVSSPEHHRIIYTRPAATASNSAPQDEHARARAKEQELGKARNPMEQYEVVEQ 322 HH R + R+ R NS Q +R A E + + N E+ + Sbjct: 119 HHNRAITHLMRSAKERV---RQDPCQDNSYMQKIRSREIAFEAQTSRYLNEFEELAI--- 172 Query: 323 IGRGAYGTAYLVHHKAERKRYVMKKIRLTKQNDKFQRTAYQEMSLMASLSNPYIVEYKDG 502 +G+G YG Y V +K + + Y +KKI + +E+ ++A L +P IV Y Sbjct: 173 LGKGGYGRVYKVRNKLDGQHYAIKKILIKSATKTDCMKVLREVKVLAGLQHPNIVGYHTA 232 Query: 503 WVD 511 W++ Sbjct: 233 WIE 235
>STK3_MOUSE (Q9JI10) Serine/threonine-protein kinase 3 (EC 2.7.11.1)| (STE20-like kinase MST2) (MST-2) (Mammalian STE20-like protein kinase 2) Length = 497 Score = 50.8 bits (120), Expect = 3e-06 Identities = 27/105 (25%), Positives = 54/105 (51%) Frame = +2 Query: 263 KEQELGKARNPMEQYEVVEQIGRGAYGTAYLVHHKAERKRYVMKKIRLTKQNDKFQRTAY 442 K E + P E ++V+E++G G+YG+ + HK + +K++ + + Sbjct: 13 KLSEDSLTKQPEEVFDVLEKLGEGSYGSVFKAIHKESGQVVAIKQVPVESDLQEI----I 68 Query: 443 QEMSLMASLSNPYIVEYKDGWVDEGTSVCIVTSYCEGGDMAQRIK 577 +E+S+M +PY+V+Y + + T + IV YC G ++ I+ Sbjct: 69 KEISIMQQCDSPYVVKYYGSYF-KNTDLWIVMEYCGAGSVSDIIR 112
>PAK1_MOUSE (O88643) Serine/threonine-protein kinase PAK 1 (EC 2.7.11.1)| (p21-activated kinase 1) (PAK-1) (P65-PAK) (Alpha-PAK) (CDC42/RAC effector kinase PAK-A) Length = 545 Score = 50.4 bits (119), Expect = 4e-06 Identities = 43/162 (26%), Positives = 68/162 (41%), Gaps = 33/162 (20%) Frame = +2 Query: 176 PEHHRIIYTRP------------------AATASNSAPQDEHARARAKEQE--------- 274 PEH + +YTR + T +N+ P D R K+++ Sbjct: 194 PEHTKSVYTRSVIEPLPVTPTRDVATSPISPTENNTTPPDALTRNTEKQKKKPKMSDEEI 253 Query: 275 LGKARN------PMEQYEVVEQIGRGAYGTAYLVHHKAERKRYVMKKIRLTKQNDKFQRT 436 L K R+ P ++Y E+IG+GA GT Y A + +K++ L +Q K Sbjct: 254 LEKLRSIVSVGDPKKKYTPFEKIGQGASGTVYTAMDVATGQEVAIKQMNLQQQPKK--EL 311 Query: 437 AYQEMSLMASLSNPYIVEYKDGWVDEGTSVCIVTSYCEGGDM 562 E+ +M NP IV Y D ++ G + +V Y GG + Sbjct: 312 IINEILVMRENKNPNIVNYLDSYL-VGDELWVVMEYLAGGSL 352
>STK4_HUMAN (Q13043) Serine/threonine-protein kinase 4 (EC 2.7.11.1)| (STE20-like kinase MST1) (MST-1) (Mammalian STE20-like protein kinase 1) (Serine/threonine-protein kinase Krs-2) Length = 487 Score = 50.4 bits (119), Expect = 4e-06 Identities = 28/109 (25%), Positives = 55/109 (50%) Frame = +2 Query: 251 RARAKEQELGKARNPMEQYEVVEQIGRGAYGTAYLVHHKAERKRYVMKKIRLTKQNDKFQ 430 R K E + P E ++V+E++G G+YG+ Y HK + +K++ + + Sbjct: 12 RQLKKLDEDSLTKQPEEVFDVLEKLGEGSYGSVYKAIHKETGQIVAIKQVPVESDLQEI- 70 Query: 431 RTAYQEMSLMASLSNPYIVEYKDGWVDEGTSVCIVTSYCEGGDMAQRIK 577 +E+S+M +P++V+Y + + T + IV YC G ++ I+ Sbjct: 71 ---IKEISIMQQCDSPHVVKYYGSYF-KNTDLWIVMEYCGAGSVSDIIR 115
>ATG1_ASPFU (Q4WPF2) Serine/threonine-protein kinase atg1 (EC 2.7.11.1)| (Autophagy-related protein 1) Length = 973 Score = 50.4 bits (119), Expect = 4e-06 Identities = 31/107 (28%), Positives = 55/107 (51%), Gaps = 1/107 (0%) Frame = +2 Query: 263 KEQELGKARNPMEQYEVVEQIGRGAYGTAYLVHHKAERKRYVMKKIRLTKQNDKFQRTAY 442 + +E + + +Y +++IGRG++ T Y H R +K + L+K N K + Sbjct: 9 RSRETPQPEMSIGRYTRLDEIGRGSFATVYQGVHTKTRTYVAIKSVNLSKLNKKLKDNLS 68 Query: 443 QEMSLMASLSNPYIVEYKDGWVDEGTS-VCIVTSYCEGGDMAQRIKK 580 E+ ++ L +P+IV D E TS + +V YC GD++ IK+ Sbjct: 69 SEIHILKGLYHPHIVALID--CHETTSHIHLVMEYCALGDLSLFIKR 113
>PAK1_HUMAN (Q13153) Serine/threonine-protein kinase PAK 1 (EC 2.7.11.1)| (p21-activated kinase 1) (PAK-1) (P65-PAK) (Alpha-PAK) Length = 545 Score = 50.1 bits (118), Expect = 5e-06 Identities = 43/162 (26%), Positives = 68/162 (41%), Gaps = 33/162 (20%) Frame = +2 Query: 176 PEHHRIIYTRP------------------AATASNSAPQDEHARARAKEQE--------- 274 PEH + +YTR + T +N+ P D R K+++ Sbjct: 194 PEHTKSVYTRSVIEPLPVTPTRDVATSPISPTENNTTPPDALTRNTEKQKKKPKMSDEEI 253 Query: 275 LGKARN------PMEQYEVVEQIGRGAYGTAYLVHHKAERKRYVMKKIRLTKQNDKFQRT 436 L K R+ P ++Y E+IG+GA GT Y A + +K++ L +Q K Sbjct: 254 LEKLRSIVSVGDPKKKYTRFEKIGQGASGTVYTAMDVATGQEVAIKQMNLQQQPKK--EL 311 Query: 437 AYQEMSLMASLSNPYIVEYKDGWVDEGTSVCIVTSYCEGGDM 562 E+ +M NP IV Y D ++ G + +V Y GG + Sbjct: 312 IINEILVMRENKNPNIVNYLDSYL-VGDELWVVMEYLAGGSL 352
>PAK1_RAT (P35465) Serine/threonine-protein kinase PAK 1 (EC 2.7.11.1)| (p21-activated kinase 1) (PAK-1) (P68-PAK) (Alpha-PAK) (Protein kinase MUK2) Length = 544 Score = 50.1 bits (118), Expect = 5e-06 Identities = 43/162 (26%), Positives = 68/162 (41%), Gaps = 33/162 (20%) Frame = +2 Query: 176 PEHHRIIYTRP------------------AATASNSAPQDEHARARAKEQE--------- 274 PEH + +YTR + T +N+ P D R K+++ Sbjct: 193 PEHTKSVYTRSVIEPLPVTPTRDVATSPISPTENNTTPPDALTRNTEKQKKKPKMSDEEI 252 Query: 275 LGKARN------PMEQYEVVEQIGRGAYGTAYLVHHKAERKRYVMKKIRLTKQNDKFQRT 436 L K R+ P ++Y E+IG+GA GT Y A + +K++ L +Q K Sbjct: 253 LEKLRSIVSVGDPKKKYTRFEKIGQGASGTVYTAMDVATGQEVAIKQMNLQQQPKK--EL 310 Query: 437 AYQEMSLMASLSNPYIVEYKDGWVDEGTSVCIVTSYCEGGDM 562 E+ +M NP IV Y D ++ G + +V Y GG + Sbjct: 311 IINEILVMRENKNPNIVNYLDSYL-VGDELWVVMEYLAGGSL 351
>PKND_CHLMU (Q9PK92) Serine/threonine-protein kinase pknD (EC 2.7.11.1)| Length = 934 Score = 50.1 bits (118), Expect = 5e-06 Identities = 32/95 (33%), Positives = 47/95 (49%), Gaps = 1/95 (1%) Frame = +2 Query: 296 MEQYEVVEQIGRGAYGTAYLVHHKAERKRYVMKKIRLTKQNDKFQRTAY-QEMSLMASLS 472 M++YE++ IGRG G YL H KA +R +KKIR ++ R + +E + A L Sbjct: 1 MQRYELIRLIGRGGMGEVYLAHDKACSRRVALKKIREDLSDNPLLRKRFLREAKIAADLI 60 Query: 473 NPYIVEYKDGWVDEGTSVCIVTSYCEGGDMAQRIK 577 +P IV +G SV Y EG + +K Sbjct: 61 HPGIVPVY-SICSDGESVYYTMPYIEGFSLKHLLK 94
>KS6A_CAEEL (Q21734) Putative ribosomal protein S6 kinase alpha (EC 2.7.11.1)| Length = 784 Score = 50.1 bits (118), Expect = 5e-06 Identities = 36/141 (25%), Positives = 71/141 (50%), Gaps = 2/141 (1%) Frame = +2 Query: 158 ALPVSSPEHHRIIYTRPAATASNSAPQDEHARARAKEQELGKARNPM-EQYEVVEQIGRG 334 ALP S+ H R + SN+ ++ A++ NP + YE++E+IG G Sbjct: 407 ALPASANGHEIF---RGFSFVSNAVMEERKLIAKSVRSVPTAKTNPFTDDYEILEKIGNG 463 Query: 335 AYGTAYLVHHKAERKRYVMKKIRLTKQNDKFQRTAYQEMSLMASLS-NPYIVEYKDGWVD 511 A+ + KA R++Y +K ++ K A +E+ ++ S + ++V+ D + D Sbjct: 464 AHSVVHKCQMKATRRKYAVKIVK------KAVFDATEEVDILLRHSHHQFVVKLFDVYED 517 Query: 512 EGTSVCIVTSYCEGGDMAQRI 574 E T++ ++ CEGG++ ++ Sbjct: 518 E-TAIYMIEELCEGGELLDKL 537 Score = 45.1 bits (105), Expect = 1e-04 Identities = 26/107 (24%), Positives = 58/107 (54%), Gaps = 3/107 (2%) Frame = +2 Query: 269 QELGKARNPMEQYEVVEQIGRGAYGTAYLVHHKAERKR---YVMKKIRLTKQNDKFQRTA 439 ++ G+ +P Q+E+++ +G+G++G +LV R Y MK ++ + ++ Sbjct: 93 RKCGEKADP-RQFELLKVLGQGSFGKVFLVRKVRGRDSGHVYAMKVLKKATLKVRDRQRT 151 Query: 440 YQEMSLMASLSNPYIVEYKDGWVDEGTSVCIVTSYCEGGDMAQRIKK 580 E +++A +S+P+IV+ + EG + ++ + GGD+ R+ K Sbjct: 152 KLERNILAHISHPFIVKLHYAFQTEG-KLYLILDFLRGGDLFTRLSK 197
>CDK3_MOUSE (Q80YP0) Truncated cell division protein kinase 3 homolog| Length = 186 Score = 49.7 bits (117), Expect = 6e-06 Identities = 24/68 (35%), Positives = 39/68 (57%) Frame = +2 Query: 296 MEQYEVVEQIGRGAYGTAYLVHHKAERKRYVMKKIRLTKQNDKFQRTAYQEMSLMASLSN 475 M+ ++ VE+IG G YG Y +K + +KKIRL + + TA +E+SL+ L + Sbjct: 1 MDVFQKVEKIGEGTYGVVYKARNKVTGQLVALKKIRLDLEAEGVPSTAVREISLLKELKH 60 Query: 476 PYIVEYKD 499 P I++ D Sbjct: 61 PNIIKLLD 68
>SAPK2_ORYSA (Q84TC6) Serine/threonine-protein kinase SAPK2 (EC 2.7.11.1)| (Osmotic stress/abscisic acid-activated protein kinase 2) Length = 339 Score = 49.7 bits (117), Expect = 6e-06 Identities = 31/93 (33%), Positives = 50/93 (53%) Frame = +2 Query: 296 MEQYEVVEQIGRGAYGTAYLVHHKAERKRYVMKKIRLTKQNDKFQRTAYQEMSLMASLSN 475 ME+YEV++ IG G +G A LV ++ + +K I ++ K +E+ SL + Sbjct: 1 MERYEVIKDIGSGNFGVAKLVRDVRTKELFAVKFI---ERGQKIDENVQREIMNHRSLRH 57 Query: 476 PYIVEYKDGWVDEGTSVCIVTSYCEGGDMAQRI 574 P IV +K+ V T + IV Y GG++ +RI Sbjct: 58 PNIVRFKE-VVLTPTHLAIVMEYAAGGELFERI 89
>ASK2_ARATH (P43292) Serine/threonine-protein kinase ASK2 (EC 2.7.11.1)| Length = 353 Score = 49.7 bits (117), Expect = 6e-06 Identities = 29/93 (31%), Positives = 50/93 (53%) Frame = +2 Query: 296 MEQYEVVEQIGRGAYGTAYLVHHKAERKRYVMKKIRLTKQNDKFQRTAYQEMSLMASLSN 475 M++Y+VV+ +G G +G A L+ HK ++ MK I ++ K +E+ SL + Sbjct: 1 MDKYDVVKDLGAGNFGVARLLRHKDTKELVAMKYI---ERGRKIDENVAREIINHRSLKH 57 Query: 476 PYIVEYKDGWVDEGTSVCIVTSYCEGGDMAQRI 574 P I+ +K+ + T + IV Y GG++ RI Sbjct: 58 PNIIRFKE-VILTPTHLAIVMEYASGGELFDRI 89
>STK36_PONPY (Q5RAJ5) Serine/threonine-protein kinase 36 (EC 2.7.11.1) (Fused| homolog) Length = 1315 Score = 49.3 bits (116), Expect = 8e-06 Identities = 28/86 (32%), Positives = 44/86 (51%) Frame = +2 Query: 296 MEQYEVVEQIGRGAYGTAYLVHHKAERKRYVMKKIRLTKQNDKFQRTAYQEMSLMASLSN 475 ME+Y V+E IG G++G Y K + +K I +++K R +E+ +M L + Sbjct: 1 MEKYHVLEMIGEGSFGRVYKGRRKYSAQVVALKFIPKLGRSEKELRNLQREIEIMRGLRH 60 Query: 476 PYIVEYKDGWVDEGTSVCIVTSYCEG 553 P IV D + + V +VT Y EG Sbjct: 61 PNIVHMLDSF-ETDKEVVVVTDYAEG 85
>STK36_HUMAN (Q9NRP7) Serine/threonine-protein kinase 36 (EC 2.7.11.1) (Fused| homolog) Length = 1315 Score = 49.3 bits (116), Expect = 8e-06 Identities = 28/86 (32%), Positives = 44/86 (51%) Frame = +2 Query: 296 MEQYEVVEQIGRGAYGTAYLVHHKAERKRYVMKKIRLTKQNDKFQRTAYQEMSLMASLSN 475 ME+Y V+E IG G++G Y K + +K I +++K R +E+ +M L + Sbjct: 1 MEKYHVLEMIGEGSFGRVYKGRRKYSAQVVALKFIPKLGRSEKELRNLQREIEIMRGLRH 60 Query: 476 PYIVEYKDGWVDEGTSVCIVTSYCEG 553 P IV D + + V +VT Y EG Sbjct: 61 PNIVHMLDSF-ETDKEVVVVTDYAEG 85
>CDPK1_PLAYO (Q7RAH3) Calcium-dependent protein kinase 1 (EC 2.7.11.1)| Length = 534 Score = 49.3 bits (116), Expect = 8e-06 Identities = 37/117 (31%), Positives = 59/117 (50%), Gaps = 11/117 (9%) Frame = +2 Query: 257 RAKEQELGKARNPMEQYEVVEQIGRGAYGTAYLVHHK---AERKRYVMKKIRLTKQN--- 418 R KE ++G E Y V ++G GAYG L K +E+ V+KK + K Sbjct: 46 RKKEGKIG------ESYFKVRKLGSGAYGEVLLCKEKNGHSEKAIKVIKKSQFDKGRYND 99 Query: 419 -----DKFQRTAYQEMSLMASLSNPYIVEYKDGWVDEGTSVCIVTSYCEGGDMAQRI 574 +KF Y E+SL+ SL +P I++ D + D+ +VT + EGG++ ++I Sbjct: 100 DNKNIEKFHEEIYNEISLLKSLDHPNIIKLFDVFEDK-KYFYLVTEFYEGGELFEQI 155
>PAK3_RAT (Q62829) Serine/threonine-protein kinase PAK 3 (EC 2.7.11.1)| (p21-activated kinase 3) (PAK-3) (Beta-PAK) (p65-PAK) Length = 544 Score = 49.3 bits (116), Expect = 8e-06 Identities = 47/159 (29%), Positives = 68/159 (42%), Gaps = 30/159 (18%) Frame = +2 Query: 176 PEHHRIIYTRPA--ATASNSAPQDEHA-----------------RARAK-----EQELGK 283 PEH + IYTR + AS +AP E R R K E+ L K Sbjct: 195 PEHTKSIYTRSVVESIASPAAPNKEATPPSAENANSSTLYRNTDRQRKKSKMTDEEILEK 254 Query: 284 ARN------PMEQYEVVEQIGRGAYGTAYLVHHKAERKRYVMKKIRLTKQNDKFQRTAYQ 445 R+ P ++Y E+IG+GA GT Y A + +K++ L +Q K Sbjct: 255 LRSIVSVGDPKKKYTRFEKIGQGASGTVYTALDIATGQEVAIKQMNLQQQPKK--ELIIN 312 Query: 446 EMSLMASLSNPYIVEYKDGWVDEGTSVCIVTSYCEGGDM 562 E+ +M NP IV Y D ++ G + +V Y GG + Sbjct: 313 EILVMRENKNPNIVNYLDSYL-VGDELWVVMEYLAGGSL 350
>CDKL5_HUMAN (O76039) Cyclin-dependent kinase-like 5 (EC 2.7.11.22)| (Serine/threonine-protein kinase 9) Length = 1030 Score = 49.3 bits (116), Expect = 8e-06 Identities = 24/87 (27%), Positives = 47/87 (54%) Frame = +2 Query: 290 NPMEQYEVVEQIGRGAYGTAYLVHHKAERKRYVMKKIRLTKQNDKFQRTAYQEMSLMASL 469 N M ++E++ +G GAYG HK + +KK + +++N++ + T +E+ ++ +L Sbjct: 8 NVMNKFEILGVVGEGAYGVVLKCRHKETHEIVAIKKFKDSEENEEVKETTLRELKMLRTL 67 Query: 470 SNPYIVEYKDGWVDEGTSVCIVTSYCE 550 IVE K+ + G + +V Y E Sbjct: 68 KQENIVELKEAFRRRG-KLYLVFEYVE 93
>CDC2_DROME (P23572) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) Length = 297 Score = 49.3 bits (116), Expect = 8e-06 Identities = 26/73 (35%), Positives = 41/73 (56%) Frame = +2 Query: 296 MEQYEVVEQIGRGAYGTAYLVHHKAERKRYVMKKIRLTKQNDKFQRTAYQEMSLMASLSN 475 ME +E +E+IG G YG Y ++ + MKKIRL ++ TA +E+SL+ L + Sbjct: 1 MEDFEKIEKIGEGTYGVVYKGRNRLTGQIVAMKKIRLESDDEGVPSTAIREISLLKELKH 60 Query: 476 PYIVEYKDGWVDE 514 IV +D ++E Sbjct: 61 ENIVCLEDVLMEE 73
>PAK3_PONPY (Q7YQL3) Serine/threonine-protein kinase PAK 3 (EC 2.7.11.1)| (p21-activated kinase 3) (PAK-3) Length = 559 Score = 49.3 bits (116), Expect = 8e-06 Identities = 45/159 (28%), Positives = 70/159 (44%), Gaps = 30/159 (18%) Frame = +2 Query: 176 PEHHRIIYTR------------------PAATASNSAP---QDEHARARAK---EQELGK 283 PEH + IYTR P+A +NS+ + R ++K E+ L K Sbjct: 210 PEHTKSIYTRSVVESIASPAVPNKEVTPPSAENANSSTLYRNTDRQRKKSKMTDEEILEK 269 Query: 284 ARN------PMEQYEVVEQIGRGAYGTAYLVHHKAERKRYVMKKIRLTKQNDKFQRTAYQ 445 R+ P ++Y E+IG+GA GT Y A + +K++ L +Q K Sbjct: 270 LRSIVSVGDPKKKYTRFEKIGQGASGTVYTALDIATGQEVAIKQMNLQQQPKK--ELIIN 327 Query: 446 EMSLMASLSNPYIVEYKDGWVDEGTSVCIVTSYCEGGDM 562 E+ +M NP IV Y D ++ G + +V Y GG + Sbjct: 328 EILVMRENKNPNIVNYLDSYL-VGDELWVVMEYLAGGSL 365
>PAK3_PANTR (Q7YQL4) Serine/threonine-protein kinase PAK 3 (EC 2.7.11.1)| (p21-activated kinase 3) (PAK-3) Length = 559 Score = 49.3 bits (116), Expect = 8e-06 Identities = 45/159 (28%), Positives = 70/159 (44%), Gaps = 30/159 (18%) Frame = +2 Query: 176 PEHHRIIYTR------------------PAATASNSAP---QDEHARARAK---EQELGK 283 PEH + IYTR P+A +NS+ + R ++K E+ L K Sbjct: 210 PEHTKSIYTRSVVESIASPAVPNKEVTPPSAENANSSTLYRNTDRQRKKSKMTDEEILEK 269 Query: 284 ARN------PMEQYEVVEQIGRGAYGTAYLVHHKAERKRYVMKKIRLTKQNDKFQRTAYQ 445 R+ P ++Y E+IG+GA GT Y A + +K++ L +Q K Sbjct: 270 LRSIVSVGDPKKKYTRFEKIGQGASGTVYTALDIATGQEVAIKQMNLQQQPKK--ELIIN 327 Query: 446 EMSLMASLSNPYIVEYKDGWVDEGTSVCIVTSYCEGGDM 562 E+ +M NP IV Y D ++ G + +V Y GG + Sbjct: 328 EILVMRENKNPNIVNYLDSYL-VGDELWVVMEYLAGGSL 365
>PAK3_MOUSE (Q61036) Serine/threonine-protein kinase PAK 3 (EC 2.7.11.1)| (p21-activated kinase 3) (PAK-3) (Beta-PAK) (CDC42/RAC effector kinase PAK-B) Length = 559 Score = 49.3 bits (116), Expect = 8e-06 Identities = 47/159 (29%), Positives = 68/159 (42%), Gaps = 30/159 (18%) Frame = +2 Query: 176 PEHHRIIYTRPA--ATASNSAPQDEHA-----------------RARAK-----EQELGK 283 PEH + IYTR + AS +AP E R R K E+ L K Sbjct: 210 PEHTKSIYTRSVVESIASPAAPNKEDIPPSAENANSTTLYRNTDRQRKKSKMTDEEILEK 269 Query: 284 ARN------PMEQYEVVEQIGRGAYGTAYLVHHKAERKRYVMKKIRLTKQNDKFQRTAYQ 445 R+ P ++Y E+IG+GA GT Y A + +K++ L +Q K Sbjct: 270 LRSIVSVGDPKKKYTRFEKIGQGASGTVYTALDIATGQEVAIKQMNLQQQPKK--ELIIN 327 Query: 446 EMSLMASLSNPYIVEYKDGWVDEGTSVCIVTSYCEGGDM 562 E+ +M NP IV Y D ++ G + +V Y GG + Sbjct: 328 EILVMRENKNPNIVNYLDSYL-VGDELWVVMEYLAGGSL 365
>PAK3_HUMAN (O75914) Serine/threonine-protein kinase PAK 3 (EC 2.7.11.1)| (p21-activated kinase 3) (PAK-3) (Beta-PAK) (Oligophrenin-3) Length = 559 Score = 49.3 bits (116), Expect = 8e-06 Identities = 45/159 (28%), Positives = 70/159 (44%), Gaps = 30/159 (18%) Frame = +2 Query: 176 PEHHRIIYTR------------------PAATASNSAP---QDEHARARAK---EQELGK 283 PEH + IYTR P+A +NS+ + R ++K E+ L K Sbjct: 210 PEHTKSIYTRSVVESIASPAVPNKEVTPPSAENANSSTLYRNTDRQRKKSKMTDEEILEK 269 Query: 284 ARN------PMEQYEVVEQIGRGAYGTAYLVHHKAERKRYVMKKIRLTKQNDKFQRTAYQ 445 R+ P ++Y E+IG+GA GT Y A + +K++ L +Q K Sbjct: 270 LRSIVSVGDPKKKYTRFEKIGQGASGTVYTALDIATGQEVAIKQMNLQQQPKK--ELIIN 327 Query: 446 EMSLMASLSNPYIVEYKDGWVDEGTSVCIVTSYCEGGDM 562 E+ +M NP IV Y D ++ G + +V Y GG + Sbjct: 328 EILVMRENKNPNIVNYLDSYL-VGDELWVVMEYLAGGSL 365
>NEK9_XENLA (Q7ZZC8) Serine/threonine-protein kinase Nek9 (EC 2.7.11.1)| (NimA-related protein kinase 9) (XNek9) (Nercc1 kinase) Length = 944 Score = 49.3 bits (116), Expect = 8e-06 Identities = 26/90 (28%), Positives = 48/90 (53%) Frame = +2 Query: 305 YEVVEQIGRGAYGTAYLVHHKAERKRYVMKKIRLTKQNDKFQRTAYQEMSLMASLSNPYI 484 Y + +G GAYG A L + V K++ L + ++K +R A E+ +++ L + I Sbjct: 34 YIPIRVLGHGAYGEATLYRRTEDDSLVVWKEVGLARLSEKERRDALNEIVILSLLQHDNI 93 Query: 485 VEYKDGWVDEGTSVCIVTSYCEGGDMAQRI 574 + Y + ++D T + I YC GG++ +I Sbjct: 94 IAYYNHFLDSNT-LLIELEYCNGGNLFDKI 122
>CDC2_EMENI (Q00646) Cell division control protein 2 (EC 2.7.11.22) (EC| 2.7.11.23) (Cyclin-dependent protein kinase) Length = 323 Score = 49.3 bits (116), Expect = 8e-06 Identities = 25/65 (38%), Positives = 38/65 (58%), Gaps = 1/65 (1%) Frame = +2 Query: 296 MEQYEVVEQIGRGAYGTAYLVHHKAERKRYV-MKKIRLTKQNDKFQRTAYQEMSLMASLS 472 ME Y+ +E+IG G YG Y R V +KKIRL +++ TA +E+SL+ ++ Sbjct: 1 MENYQKIEKIGEGTYGVVYKARELTHPNRIVALKKIRLEAEDEGVPSTAIREISLLKEMN 60 Query: 473 NPYIV 487 +P IV Sbjct: 61 DPNIV 65
>CC2H2_TRYBB (P54665) Cell division control protein 2 homolog 2 (EC 2.7.11.22)| Length = 345 Score = 48.9 bits (115), Expect = 1e-05 Identities = 25/84 (29%), Positives = 44/84 (52%) Frame = +2 Query: 299 EQYEVVEQIGRGAYGTAYLVHHKAERKRYVMKKIRLTKQNDKFQRTAYQEMSLMASLSNP 478 ++Y +E++G G+YG Y H + MK+I L + TA +E+SL+ L++P Sbjct: 44 DRYSRIEKVGEGSYGIVYKCHDNFTGRTVAMKRIPLIVNDGGVPSTAVREVSLLRELNHP 103 Query: 479 YIVEYKDGWVDEGTSVCIVTSYCE 550 Y+V D + E + ++ Y E Sbjct: 104 YVVRLLDVVLHE-AKLLLIFEYME 126
>CDPK1_PLAFK (P62343) Calcium-dependent protein kinase 1 (EC 2.7.11.1) (PfCPK)| (PfCDPK1) Length = 523 Score = 48.9 bits (115), Expect = 1e-05 Identities = 37/119 (31%), Positives = 58/119 (48%), Gaps = 13/119 (10%) Frame = +2 Query: 257 RAKEQELGKARNPMEQYEVVEQIGRGAYGTAYLVHHK---AERKRYVMKKIRLTKQ---- 415 R KE ++G E Y V ++G GAYG L K E+ V+KK + K Sbjct: 45 RKKEGKIG------ESYFKVRKLGSGAYGEVLLCREKHGHGEKAIKVIKKSQFDKMKYSI 98 Query: 416 ------NDKFQRTAYQEMSLMASLSNPYIVEYKDGWVDEGTSVCIVTSYCEGGDMAQRI 574 +DK Y E+SL+ SL +P I++ D + D+ +VT + EGG++ ++I Sbjct: 99 TNKIECDDKIHEEIYNEISLLKSLDHPNIIKLFDVFEDK-KYFYLVTEFYEGGELFEQI 156
>CDPK1_PLAF7 (P62344) Calcium-dependent protein kinase 1 (EC 2.7.11.1)| Length = 523 Score = 48.9 bits (115), Expect = 1e-05 Identities = 37/119 (31%), Positives = 58/119 (48%), Gaps = 13/119 (10%) Frame = +2 Query: 257 RAKEQELGKARNPMEQYEVVEQIGRGAYGTAYLVHHK---AERKRYVMKKIRLTKQ---- 415 R KE ++G E Y V ++G GAYG L K E+ V+KK + K Sbjct: 45 RKKEGKIG------ESYFKVRKLGSGAYGEVLLCREKHGHGEKAIKVIKKSQFDKMKYSI 98 Query: 416 ------NDKFQRTAYQEMSLMASLSNPYIVEYKDGWVDEGTSVCIVTSYCEGGDMAQRI 574 +DK Y E+SL+ SL +P I++ D + D+ +VT + EGG++ ++I Sbjct: 99 TNKIECDDKIHEEIYNEISLLKSLDHPNIIKLFDVFEDK-KYFYLVTEFYEGGELFEQI 156
>CDK3_HUMAN (Q00526) Cell division protein kinase 3 (EC 2.7.11.22)| Length = 305 Score = 48.5 bits (114), Expect = 1e-05 Identities = 24/68 (35%), Positives = 38/68 (55%) Frame = +2 Query: 296 MEQYEVVEQIGRGAYGTAYLVHHKAERKRYVMKKIRLTKQNDKFQRTAYQEMSLMASLSN 475 M+ ++ VE+IG G YG Y ++ + +KKIRL + + TA +E+SL+ L + Sbjct: 1 MDMFQKVEKIGEGTYGVVYKAKNRETGQLVALKKIRLDLEMEGVPSTAIREISLLKELKH 60 Query: 476 PYIVEYKD 499 P IV D Sbjct: 61 PNIVRLLD 68
>CDC2H_PLACH (Q4Y4B1) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) Length = 288 Score = 48.5 bits (114), Expect = 1e-05 Identities = 24/68 (35%), Positives = 42/68 (61%) Frame = +2 Query: 296 MEQYEVVEQIGRGAYGTAYLVHHKAERKRYVMKKIRLTKQNDKFQRTAYQEMSLMASLSN 475 ME+Y +E+IG G YG Y + ++ + + +KKIRL K+++ TA +E+S++ L + Sbjct: 1 MEKYHGLEKIGEGTYGVVYKAQN-SDGESFALKKIRLEKEDEGIPSTAIREISILKELRH 59 Query: 476 PYIVEYKD 499 IV+ D Sbjct: 60 SNIVKLYD 67
>CDC2H_PLABA (Q4Z6R1) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) Length = 288 Score = 48.5 bits (114), Expect = 1e-05 Identities = 24/68 (35%), Positives = 42/68 (61%) Frame = +2 Query: 296 MEQYEVVEQIGRGAYGTAYLVHHKAERKRYVMKKIRLTKQNDKFQRTAYQEMSLMASLSN 475 ME+Y +E+IG G YG Y + ++ + + +KKIRL K+++ TA +E+S++ L + Sbjct: 1 MEKYHGLEKIGEGTYGVVYKAQN-SDGESFALKKIRLEKEDEGIPSTAIREISILKELRH 59 Query: 476 PYIVEYKD 499 IV+ D Sbjct: 60 SNIVKLYD 67
>CDC2_AJECA (P54119) Cell division control protein 2 (EC 2.7.11.22) (EC| 2.7.11.23) (Cyclin-dependent protein kinase) Length = 324 Score = 48.1 bits (113), Expect = 2e-05 Identities = 25/65 (38%), Positives = 37/65 (56%), Gaps = 1/65 (1%) Frame = +2 Query: 296 MEQYEVVEQIGRGAYGTAYLVHHKAERKRYV-MKKIRLTKQNDKFQRTAYQEMSLMASLS 472 ME Y+ +E+IG G YG Y R V +KKIRL +++ TA +E+SL+ + Sbjct: 1 MENYQKIEKIGEGTYGVVYKARDLTHPNRIVALKKIRLEAEDEGVPSTAIREISLLKEMH 60 Query: 473 NPYIV 487 +P IV Sbjct: 61 DPNIV 65
>CDPK_SOYBN (P28583) Calcium-dependent protein kinase SK5 (EC 2.7.11.1) (CDPK)| Length = 508 Score = 48.1 bits (113), Expect = 2e-05 Identities = 34/123 (27%), Positives = 59/123 (47%), Gaps = 1/123 (0%) Frame = +2 Query: 209 AATASNSAPQDEHARARAKEQELGKARNPMEQYEVVEQIGRGAYGTAYLVHHKAERKRYV 388 AA +S+S+ +A + +N E YEV ++G+G +GT + +A ++ Sbjct: 2 AAKSSSSSTTTNVVTLKAAWVLPQRTQNIREVYEVGRKLGQGQFGTTFECTRRASGGKFA 61 Query: 389 MKKIRLTKQNDKFQ-RTAYQEMSLMASLSNPYIVEYKDGWVDEGTSVCIVTSYCEGGDMA 565 K I K K ++E+ +M LS V +G ++ T+V +V CEGG++ Sbjct: 62 CKSIPKRKLLCKEDYEDVWREIQIMHHLSEHANVVRIEGTYEDSTAVHLVMELCEGGELF 121 Query: 566 QRI 574 RI Sbjct: 122 DRI 124
>MYLK_DICDI (P25323) Myosin light chain kinase (EC 2.7.11.18) (MLCK)| Length = 295 Score = 48.1 bits (113), Expect = 2e-05 Identities = 23/90 (25%), Positives = 48/90 (53%) Frame = +2 Query: 305 YEVVEQIGRGAYGTAYLVHHKAERKRYVMKKIRLTKQNDKFQRTAYQEMSLMASLSNPYI 484 YE E++GRGA+ YL +K ++RY +K I ++ +++ E+ ++ +++P I Sbjct: 8 YEFKEELGRGAFSIVYLGENKQTKQRYAIKVINKSELGKDYEKNLKMEVDILKKVNHPNI 67 Query: 485 VEYKDGWVDEGTSVCIVTSYCEGGDMAQRI 574 + K+ D + +V GG++ +I Sbjct: 68 IALKE-LFDTPEKLYLVMELVTGGELFDKI 96
>STK36_MOUSE (Q69ZM6) Serine/threonine-protein kinase 36 (EC 2.7.11.1) (Fused| homolog) Length = 1268 Score = 48.1 bits (113), Expect = 2e-05 Identities = 28/86 (32%), Positives = 44/86 (51%) Frame = +2 Query: 296 MEQYEVVEQIGRGAYGTAYLVHHKAERKRYVMKKIRLTKQNDKFQRTAYQEMSLMASLSN 475 ME+Y V+E IG G++G Y K + +K I +++K R +E+ +M L + Sbjct: 1 MEKYHVLEMIGEGSFGRVYKGRKKYSAQVVALKFIPKLGRSEKELRNLQREIEIMRGLWH 60 Query: 476 PYIVEYKDGWVDEGTSVCIVTSYCEG 553 P IV D + + V +VT Y EG Sbjct: 61 PNIVHMLDSF-ETDKEVVVVTDYAEG 85
>GCN2_ARATH (Q9LX30) Probable serine/threonine-protein kinase GCN2 (EC| 2.7.11.1) Length = 1241 Score = 47.8 bits (112), Expect = 2e-05 Identities = 37/164 (22%), Positives = 64/164 (39%), Gaps = 23/164 (14%) Frame = +2 Query: 95 HTRAAAVHARSPLRDHHHQRRALPVSSPEHHR--IIYTRPAATASNSAPQDEHARARAKE 268 H A +R PL D ALP + E H I+ AS S+P A Sbjct: 338 HLLRVACTSRGPLAD------ALPQITDELHELGILSEEVLDLASKSSPDFNRTFEHAFN 391 Query: 269 QELGKARNP---------------------MEQYEVVEQIGRGAYGTAYLVHHKAERKRY 385 Q + P + +E ++ +G+G +G L +K + ++Y Sbjct: 392 QNMASTSVPQFWEPPSDSCEPNASLPSSRYLNDFEELKPLGQGGFGHVVLCKNKLDGRQY 451 Query: 386 VMKKIRLTKQNDKFQRTAYQEMSLMASLSNPYIVEYKDGWVDEG 517 +KKIRL + +E++ ++ L + ++V Y W + G Sbjct: 452 AVKKIRLKDKEIPVNSRIVREVATLSRLQHQHVVRYYQAWFETG 495
>CD2L5_MOUSE (Q69ZA1) Cell division cycle 2-like protein kinase 5 (EC 2.7.11.22)| (CDC2-related protein kinase 5) Length = 1511 Score = 47.8 bits (112), Expect = 2e-05 Identities = 20/79 (25%), Positives = 44/79 (55%) Frame = +2 Query: 263 KEQELGKARNPMEQYEVVEQIGRGAYGTAYLVHHKAERKRYVMKKIRLTKQNDKFQRTAY 442 KE+++ + +++++++ IG G YG Y K + +KK+RL + + F TA Sbjct: 691 KEKDIDWGKRCVDKFDIIGIIGEGTYGQVYKARDKDTGEMVALKKVRLDNEKEGFPITAI 750 Query: 443 QEMSLMASLSNPYIVEYKD 499 +E+ ++ L++ I+ K+ Sbjct: 751 REIKILRQLTHQSIINMKE 769
>CDC7_SCHPO (P41892) Cell division control protein 7 (EC 2.7.11.1)| Length = 1062 Score = 47.8 bits (112), Expect = 2e-05 Identities = 24/80 (30%), Positives = 42/80 (52%) Frame = +2 Query: 323 IGRGAYGTAYLVHHKAERKRYVMKKIRLTKQNDKFQRTAYQEMSLMASLSNPYIVEYKDG 502 +G+GA+G Y + + +KK++L+K E+ L+ +L +P IV+Y+ G Sbjct: 15 LGKGAFGAVYRGLNIKNGETVAVKKVKLSKMLKSDLSVIKMEIDLLKNLDHPNIVKYR-G 73 Query: 503 WVDEGTSVCIVTSYCEGGDM 562 S+CI+ YCE G + Sbjct: 74 SYQTNDSLCIILEYCENGSL 93
>SULU_CAEEL (P46549) Serine/threonine-protein kinase SULU (EC 2.7.11.1)| (Protein kinase 18) Length = 982 Score = 47.8 bits (112), Expect = 2e-05 Identities = 24/90 (26%), Positives = 52/90 (57%), Gaps = 1/90 (1%) Frame = +2 Query: 287 RNPMEQYEVVEQIGRGAYGTAYLVHHKAERKRYVMKKIRLT-KQNDKFQRTAYQEMSLMA 463 ++P ++Y+ + +IG G++G Y + K + +KK+ + KQ + +E+S + Sbjct: 24 KDPEQRYQDLREIGHGSFGAVYFAYDKKNEQTVAIKKMNFSGKQAVEKWNDILKEVSFLN 83 Query: 464 SLSNPYIVEYKDGWVDEGTSVCIVTSYCEG 553 ++ +P+IV+YK ++ + T+ +V YC G Sbjct: 84 TVVHPHIVDYKACFLKD-TTCWLVMEYCIG 112
>CD2L5_HUMAN (Q14004) Cell division cycle 2-like protein kinase 5 (EC 2.7.11.22)| (CDC2-related protein kinase 5) (Cholinesterase-related cell division controller) Length = 1512 Score = 47.8 bits (112), Expect = 2e-05 Identities = 20/79 (25%), Positives = 44/79 (55%) Frame = +2 Query: 263 KEQELGKARNPMEQYEVVEQIGRGAYGTAYLVHHKAERKRYVMKKIRLTKQNDKFQRTAY 442 KE+++ + +++++++ IG G YG Y K + +KK+RL + + F TA Sbjct: 691 KEKDIDWGKRCVDKFDIIGIIGEGTYGQVYKARDKDTGEMVALKKVRLDNEKEGFPITAI 750 Query: 443 QEMSLMASLSNPYIVEYKD 499 +E+ ++ L++ I+ K+ Sbjct: 751 REIKILRQLTHQSIINMKE 769
>NIMA_EMENI (P11837) G2-specific protein kinase nimA (EC 2.7.11.1) (Never in| mitosis) Length = 699 Score = 47.4 bits (111), Expect = 3e-05 Identities = 28/94 (29%), Positives = 49/94 (52%), Gaps = 1/94 (1%) Frame = +2 Query: 299 EQYEVVEQIGRGAYGTAYLVHHKAERKRYVMKKIRLTKQNDKFQRTAYQEMSLMASLSNP 478 ++YEV+E+IG G++G V K++ K+I K + K + E ++++SL +P Sbjct: 9 DKYEVLEKIGCGSFGIIRKVKRKSDGFILCRKEINYIKMSTKEREQLTAEFNILSSLRHP 68 Query: 479 YIVEYKDG-WVDEGTSVCIVTSYCEGGDMAQRIK 577 IV Y + + + YC GGD++ IK Sbjct: 69 NIVAYYHREHLKASQDLYLYMEYCGGGDLSMVIK 102
>E2AK1_HUMAN (Q9BQI3) Eukaryotic translation initiation factor 2-alpha kinase 1| (EC 2.7.11.1) (Heme-regulated eukaryotic initiation factor eIF-2-alpha kinase) (Heme-regulated inhibitor) (Heme-controlled repressor) (HCR) (Hemin-sensitive initiation factor Length = 630 Score = 47.4 bits (111), Expect = 3e-05 Identities = 30/118 (25%), Positives = 52/118 (44%), Gaps = 8/118 (6%) Frame = +2 Query: 182 HHRIIYTRPAATASNSAPQD--------EHARARAKEQELGKARNPMEQYEVVEQIGRGA 337 HH T +A QD + R+R E +R + ++E + +G+G Sbjct: 119 HHNRAITHLMRSAKERVRQDPCEDISRIQKIRSREVALEAQTSRY-LNEFEELAILGKGG 177 Query: 338 YGTAYLVHHKAERKRYVMKKIRLTKQNDKFQRTAYQEMSLMASLSNPYIVEYKDGWVD 511 YG Y V +K + + Y +KKI + +E+ ++A L +P IV Y W++ Sbjct: 178 YGRVYKVRNKLDGQYYAIKKILIKGATKTVCMKVLREVKVLAGLQHPNIVGYHTAWIE 235
>KAPCB_PIG (P05383) cAMP-dependent protein kinase, beta-catalytic subunit (EC| 2.7.11.11) (PKA C-beta) Length = 350 Score = 47.4 bits (111), Expect = 3e-05 Identities = 36/133 (27%), Positives = 65/133 (48%), Gaps = 9/133 (6%) Frame = +2 Query: 209 AATASNSAPQD--EHARARAKEQELGKARNP------MEQYEVVEQIGRGAYGTAYLVHH 364 AATA + + + A+AKE L K NP +E +E + +G G++G LV H Sbjct: 3 AATAKKGSEVESVKEFLAKAKEDFLKKWENPAPNNAGLEDFERKKTLGTGSFGRVMLVKH 62 Query: 365 KAERKRYVMKKIRLTKQNDKFQ-RTAYQEMSLMASLSNPYIVEYKDGWVDEGTSVCIVTS 541 KA + Y MK + K Q E ++ +++ P++V + + D +++ +V Sbjct: 63 KATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVRLEFSFKD-NSNLYMVME 121 Query: 542 YCEGGDMAQRIKK 580 Y GG+M +++ Sbjct: 122 YVPGGEMFSHLRR 134
>KAPCB_HUMAN (P22694) cAMP-dependent protein kinase, beta-catalytic subunit (EC| 2.7.11.11) (PKA C-beta) Length = 350 Score = 47.4 bits (111), Expect = 3e-05 Identities = 36/133 (27%), Positives = 65/133 (48%), Gaps = 9/133 (6%) Frame = +2 Query: 209 AATASNSAPQD--EHARARAKEQELGKARNP------MEQYEVVEQIGRGAYGTAYLVHH 364 AATA + + + A+AKE L K NP +E +E + +G G++G LV H Sbjct: 3 AATAKKGSEVESVKEFLAKAKEDFLKKWENPTQNNAGLEDFERKKTLGTGSFGRVMLVKH 62 Query: 365 KAERKRYVMKKIRLTKQNDKFQ-RTAYQEMSLMASLSNPYIVEYKDGWVDEGTSVCIVTS 541 KA + Y MK + K Q E ++ +++ P++V + + D +++ +V Sbjct: 63 KATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVRLEYAFKD-NSNLYMVME 121 Query: 542 YCEGGDMAQRIKK 580 Y GG+M +++ Sbjct: 122 YVPGGEMFSHLRR 134
>KAPCA_PIG (P36887) cAMP-dependent protein kinase, alpha-catalytic subunit (EC| 2.7.11.11) (PKA C-alpha) Length = 350 Score = 47.4 bits (111), Expect = 3e-05 Identities = 34/133 (25%), Positives = 66/133 (49%), Gaps = 9/133 (6%) Frame = +2 Query: 209 AATASNSAPQD--EHARARAKEQELGKARNP------MEQYEVVEQIGRGAYGTAYLVHH 364 AA A + Q+ + A+AKE L K NP ++Q+E ++ +G G++G LV H Sbjct: 3 AAAAKKGSEQESVKEFLAKAKEDFLKKWENPAQNTAHLDQFERIKTLGTGSFGRVMLVKH 62 Query: 365 KAERKRYVMKKIRLTKQNDKFQ-RTAYQEMSLMASLSNPYIVEYKDGWVDEGTSVCIVTS 541 K + MK + K Q E ++ +++ P++V+ + + D +++ +V Sbjct: 63 KETGNHFAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEYSFKD-NSNLYMVME 121 Query: 542 YCEGGDMAQRIKK 580 Y GG+M +++ Sbjct: 122 YVPGGEMFSHLRR 134
>KAPB1_BOVIN (P05131) cAMP-dependent protein kinase, beta-1-catalytic subunit| (EC 2.7.11.11) (PKA C-beta-1) Length = 350 Score = 47.4 bits (111), Expect = 3e-05 Identities = 36/133 (27%), Positives = 65/133 (48%), Gaps = 9/133 (6%) Frame = +2 Query: 209 AATASNSAPQD--EHARARAKEQELGKARNP------MEQYEVVEQIGRGAYGTAYLVHH 364 AATA + + + A+AKE L K NP +E +E + +G G++G LV H Sbjct: 3 AATAKKGSEVESVKEFLAKAKEDFLKKWENPAPNNAGLEDFERKKTLGTGSFGRVMLVKH 62 Query: 365 KAERKRYVMKKIRLTKQNDKFQ-RTAYQEMSLMASLSNPYIVEYKDGWVDEGTSVCIVTS 541 KA + Y MK + K Q E ++ +++ P++V + + D +++ +V Sbjct: 63 KATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVRLEYAFKD-NSNLYMVME 121 Query: 542 YCEGGDMAQRIKK 580 Y GG+M +++ Sbjct: 122 YVPGGEMFSHLRR 134
>CDC2H_PLAVI (Q9XZD6) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (Pvcrk2) Length = 288 Score = 47.0 bits (110), Expect = 4e-05 Identities = 24/68 (35%), Positives = 40/68 (58%) Frame = +2 Query: 296 MEQYEVVEQIGRGAYGTAYLVHHKAERKRYVMKKIRLTKQNDKFQRTAYQEMSLMASLSN 475 ME+Y +E+IG G YG Y + + + +KKIRL K+++ TA +E+S++ L + Sbjct: 1 MEKYHGLEKIGEGTYGVVYKAQNNYG-ETFALKKIRLEKEDEGIPSTAIREISILKELKH 59 Query: 476 PYIVEYKD 499 IV+ D Sbjct: 60 SNIVKLYD 67
>CDC2H_PLAKH (O96821) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) Length = 288 Score = 47.0 bits (110), Expect = 4e-05 Identities = 24/68 (35%), Positives = 40/68 (58%) Frame = +2 Query: 296 MEQYEVVEQIGRGAYGTAYLVHHKAERKRYVMKKIRLTKQNDKFQRTAYQEMSLMASLSN 475 ME+Y +E+IG G YG Y + + + +KKIRL K+++ TA +E+S++ L + Sbjct: 1 MEKYHGLEKIGEGTYGVVYKAQNNYG-ETFALKKIRLEKEDEGIPSTAIREISILKELKH 59 Query: 476 PYIVEYKD 499 IV+ D Sbjct: 60 SNIVKLYD 67
>NIM1_NEUCR (P48479) G2-specific protein kinase nim-1 (EC 2.7.11.1)| Length = 779 Score = 47.0 bits (110), Expect = 4e-05 Identities = 27/94 (28%), Positives = 50/94 (53%), Gaps = 1/94 (1%) Frame = +2 Query: 299 EQYEVVEQIGRGAYGTAYLVHHKAERKRYVMKKIRLTKQNDKFQRTAYQEMSLMASLSNP 478 ++YE++E+IG G++G V KA+ K+I K + K + + E S++++L +P Sbjct: 5 DKYELLEKIGHGSFGIIRKVRRKADGMILCRKEISYLKMSQKEREQLHAEFSILSTLRHP 64 Query: 479 YIVEYKDGWVDEGT-SVCIVTSYCEGGDMAQRIK 577 IV Y + T + + YC GD+ + I+ Sbjct: 65 NIVGYYHREHLKATQDLHLYMEYCGNGDLGRVIR 98
>KAPB2_BOVIN (P24256) cAMP-dependent protein kinase, beta-2-catalytic subunit| (EC 2.7.11.11) (PKA C-beta-2) Length = 397 Score = 47.0 bits (110), Expect = 4e-05 Identities = 32/116 (27%), Positives = 58/116 (50%), Gaps = 7/116 (6%) Frame = +2 Query: 254 ARAKEQELGKARNP------MEQYEVVEQIGRGAYGTAYLVHHKAERKRYVMKKIRLTKQ 415 A+AKE L K NP +E +E + +G G++G LV HKA + Y MK + K Sbjct: 67 AKAKEDFLKKWENPAPNNAGLEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKV 126 Query: 416 NDKFQ-RTAYQEMSLMASLSNPYIVEYKDGWVDEGTSVCIVTSYCEGGDMAQRIKK 580 Q E ++ +++ P++V + + D +++ +V Y GG+M +++ Sbjct: 127 VKLKQIEHTLNEKRILQAVNFPFLVRLEYAFKD-NSNLYMVMEYVPGGEMFSHLRR 181
>KAPCA_HUMAN (P17612) cAMP-dependent protein kinase, alpha-catalytic subunit (EC| 2.7.11.11) (PKA C-alpha) Length = 350 Score = 47.0 bits (110), Expect = 4e-05 Identities = 34/133 (25%), Positives = 66/133 (49%), Gaps = 9/133 (6%) Frame = +2 Query: 209 AATASNSAPQD--EHARARAKEQELGKARNP------MEQYEVVEQIGRGAYGTAYLVHH 364 AA A + Q+ + A+AKE L K +P ++Q+E ++ +G G++G LV H Sbjct: 3 AAAAKKGSEQESVKEFLAKAKEDFLKKWESPAQNTAHLDQFERIKTLGTGSFGRVMLVKH 62 Query: 365 KAERKRYVMKKIRLTKQNDKFQ-RTAYQEMSLMASLSNPYIVEYKDGWVDEGTSVCIVTS 541 K Y MK + K Q E ++ +++ P++V+ + + D +++ +V Sbjct: 63 KETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKD-NSNLYMVME 121 Query: 542 YCEGGDMAQRIKK 580 Y GG+M +++ Sbjct: 122 YVPGGEMFSHLRR 134
>PBS2_YEAST (P08018) MAP kinase kinase PBS2 (EC 2.7.12.2) (Polymyxin B| resistance protein 2) (Suppressor of fluoride sensitivity 4) Length = 668 Score = 46.6 bits (109), Expect = 5e-05 Identities = 26/93 (27%), Positives = 48/93 (51%) Frame = +2 Query: 284 ARNPMEQYEVVEQIGRGAYGTAYLVHHKAERKRYVMKKIRLTKQNDKFQRTAYQEMSLMA 463 +R +++ E ++++G G YG V HK K++RL KF R E+ ++ Sbjct: 353 SRITLDELEFLDELGHGNYGNVSKVLHKPTNVIMATKEVRLELDEAKF-RQILMELEVLH 411 Query: 464 SLSNPYIVEYKDGWVDEGTSVCIVTSYCEGGDM 562 ++PYIV++ + EG +V + Y +GG + Sbjct: 412 KCNSPYIVDFYGAFFIEG-AVYMCMEYMDGGSL 443
>ATG1_CRYNE (Q5K8D3) Serine/threonine-protein kinase ATG1 (EC 2.7.11.1)| (Autophagy-related protein 1) Length = 988 Score = 46.6 bits (109), Expect = 5e-05 Identities = 29/110 (26%), Positives = 55/110 (50%), Gaps = 3/110 (2%) Frame = +2 Query: 260 AKEQELGKARNPMEQ---YEVVEQIGRGAYGTAYLVHHKAERKRYVMKKIRLTKQNDKFQ 430 ++E+E G R+ E+ Y V +IGRG++ T Y + R +K + K K Sbjct: 9 SREKESGHHRSHKERIGNYVVGAEIGRGSFATVYKGYRSKTRVPIAIKAVSRQKLTSKLL 68 Query: 431 RTAYQEMSLMASLSNPYIVEYKDGWVDEGTSVCIVTSYCEGGDMAQRIKK 580 E++++ +++ IV D + ++ T + +V YC G D++ IK+ Sbjct: 69 ENLESEINILKVINHRNIVALTDCFKND-THIYLVMEYCSGSDLSVYIKQ 117
>E2AK1_SCHPO (O13889) Eukaryotic translation initiation factor 2-alpha kinase 1| (EC 2.7.11.1) (Heme-regulated eukaryotic initiation factor eIF-2-alpha kinase) (Heme-regulated inhibitor 1) Length = 704 Score = 46.6 bits (109), Expect = 5e-05 Identities = 19/69 (27%), Positives = 38/69 (55%) Frame = +2 Query: 305 YEVVEQIGRGAYGTAYLVHHKAERKRYVMKKIRLTKQNDKFQRTAYQEMSLMASLSNPYI 484 +E +E +G+G YG+ Y +K + Y +KKI L ++ ++E +A L++P + Sbjct: 224 FEELELLGKGGYGSVYKARNKFDGVEYALKKIPLRLRSFSTSSNIFRESRTLARLNHPNV 283 Query: 485 VEYKDGWVD 511 + + WV+ Sbjct: 284 IRFFSSWVE 292
>CDC2B_ARATH (P25859) Cell division control protein 2 homolog B (EC 2.7.11.22)| (EC 2.7.11.23) Length = 309 Score = 46.6 bits (109), Expect = 5e-05 Identities = 24/64 (37%), Positives = 33/64 (51%) Frame = +2 Query: 296 MEQYEVVEQIGRGAYGTAYLVHHKAERKRYVMKKIRLTKQNDKFQRTAYQEMSLMASLSN 475 ME+YE +E++G G YG Y K K +KK RL + TA +E+SL+ LS Sbjct: 1 MEKYEKLEKVGEGTYGKVYKAMEKGTGKLVALKKTRLEMDEEGIPPTALREISLLQMLST 60 Query: 476 PYIV 487 V Sbjct: 61 SIYV 64
>KAPCB_RAT (P68182) cAMP-dependent protein kinase, beta-catalytic subunit (EC| 2.7.11.11) (PKA C-beta) Length = 350 Score = 46.6 bits (109), Expect = 5e-05 Identities = 32/116 (27%), Positives = 57/116 (49%), Gaps = 7/116 (6%) Frame = +2 Query: 254 ARAKEQELGKARNP------MEQYEVVEQIGRGAYGTAYLVHHKAERKRYVMKKIRLTKQ 415 A+AKE L K NP +E +E + +G G++G LV HKA + Y MK + K Sbjct: 20 AKAKEDFLRKWENPPPSNAGLEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKV 79 Query: 416 NDKFQ-RTAYQEMSLMASLSNPYIVEYKDGWVDEGTSVCIVTSYCEGGDMAQRIKK 580 Q E ++ ++ P++V + + D +++ +V Y GG+M +++ Sbjct: 80 VKLKQIEHTLNEKRILQAVEFPFLVRLEYSFKD-NSNLYMVMEYVPGGEMFSHLRR 134
>KAPCB_MOUSE (P68181) cAMP-dependent protein kinase, beta-catalytic subunit (EC| 2.7.11.11) (PKA C-beta) Length = 350 Score = 46.6 bits (109), Expect = 5e-05 Identities = 32/116 (27%), Positives = 57/116 (49%), Gaps = 7/116 (6%) Frame = +2 Query: 254 ARAKEQELGKARNP------MEQYEVVEQIGRGAYGTAYLVHHKAERKRYVMKKIRLTKQ 415 A+AKE L K NP +E +E + +G G++G LV HKA + Y MK + K Sbjct: 20 AKAKEDFLRKWENPPPSNAGLEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKV 79 Query: 416 NDKFQ-RTAYQEMSLMASLSNPYIVEYKDGWVDEGTSVCIVTSYCEGGDMAQRIKK 580 Q E ++ ++ P++V + + D +++ +V Y GG+M +++ Sbjct: 80 VKLKQIEHTLNEKRILQAVEFPFLVRLEYSFKD-NSNLYMVMEYVPGGEMFSHLRR 134
>KAPCB_CRIGR (P68180) cAMP-dependent protein kinase, beta-catalytic subunit (EC| 2.7.11.11) (PKA C-beta) Length = 350 Score = 46.6 bits (109), Expect = 5e-05 Identities = 32/116 (27%), Positives = 57/116 (49%), Gaps = 7/116 (6%) Frame = +2 Query: 254 ARAKEQELGKARNP------MEQYEVVEQIGRGAYGTAYLVHHKAERKRYVMKKIRLTKQ 415 A+AKE L K NP +E +E + +G G++G LV HKA + Y MK + K Sbjct: 20 AKAKEDFLRKWENPPPSNAGLEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKV 79 Query: 416 NDKFQ-RTAYQEMSLMASLSNPYIVEYKDGWVDEGTSVCIVTSYCEGGDMAQRIKK 580 Q E ++ ++ P++V + + D +++ +V Y GG+M +++ Sbjct: 80 VKLKQIEHTLNEKRILQAVEFPFLVRLEYSFKD-NSNLYMVMEYVPGGEMFSHLRR 134
>KAPCA_SHEEP (Q9MZD9) cAMP-dependent protein kinase, alpha-catalytic subunit (EC| 2.7.11.11) (PKA C-alpha) Length = 350 Score = 46.6 bits (109), Expect = 5e-05 Identities = 34/133 (25%), Positives = 65/133 (48%), Gaps = 9/133 (6%) Frame = +2 Query: 209 AATASNSAPQD--EHARARAKEQELGKARNP------MEQYEVVEQIGRGAYGTAYLVHH 364 AA A + Q+ + A+AKE L K NP ++Q+E ++ +G G++G LV H Sbjct: 3 AAAAKKGSEQESVKEFLAKAKEDFLKKWENPAQNTAHLDQFERIKTLGTGSFGRVMLVKH 62 Query: 365 KAERKRYVMKKIRLTKQNDKFQ-RTAYQEMSLMASLSNPYIVEYKDGWVDEGTSVCIVTS 541 Y MK + K Q E ++ +++ P++V+ + + D +++ +V Sbjct: 63 TETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKD-NSNLYMVME 121 Query: 542 YCEGGDMAQRIKK 580 Y GG+M +++ Sbjct: 122 YVPGGEMFSHLRR 134
>KAPCA_BOVIN (P00517) cAMP-dependent protein kinase, alpha-catalytic subunit (EC| 2.7.11.11) (PKA C-alpha) Length = 350 Score = 46.6 bits (109), Expect = 5e-05 Identities = 34/133 (25%), Positives = 65/133 (48%), Gaps = 9/133 (6%) Frame = +2 Query: 209 AATASNSAPQD--EHARARAKEQELGKARNP------MEQYEVVEQIGRGAYGTAYLVHH 364 AA A + Q+ + A+AKE L K NP ++Q+E ++ +G G++G LV H Sbjct: 3 AAAAKKGSEQESVKEFLAKAKEDFLKKWENPAQNTAHLDQFERIKTLGTGSFGRVMLVKH 62 Query: 365 KAERKRYVMKKIRLTKQNDKFQ-RTAYQEMSLMASLSNPYIVEYKDGWVDEGTSVCIVTS 541 Y MK + K Q E ++ +++ P++V+ + + D +++ +V Sbjct: 63 METGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKD-NSNLYMVME 121 Query: 542 YCEGGDMAQRIKK 580 Y GG+M +++ Sbjct: 122 YVPGGEMFSHLRR 134
>ATG1_EMENI (Q5BCU8) Serine/threonine-protein kinase atg1 (EC 2.7.11.1)| (Autophagy-related protein 1) Length = 935 Score = 46.6 bits (109), Expect = 5e-05 Identities = 25/92 (27%), Positives = 47/92 (51%) Frame = +2 Query: 305 YEVVEQIGRGAYGTAYLVHHKAERKRYVMKKIRLTKQNDKFQRTAYQEMSLMASLSNPYI 484 Y ++ IG+G++ T Y R +K + L K N K + E+ ++ L +P+I Sbjct: 24 YTRLDHIGKGSFATVYRGVQTKSRTFVAIKSVNLGKLNRKLKDNLAMEIDILKYLLHPHI 83 Query: 485 VEYKDGWVDEGTSVCIVTSYCEGGDMAQRIKK 580 V D ++ + + ++ YC GD++Q IK+ Sbjct: 84 VALLD-CLETNSHIHLIMEYCALGDLSQFIKR 114
>SPS1_YEAST (P08458) Sporulation-specific protein 1 (EC 2.7.11.1)| Length = 490 Score = 46.2 bits (108), Expect = 7e-05 Identities = 28/107 (26%), Positives = 51/107 (47%) Frame = +2 Query: 260 AKEQELGKARNPMEQYEVVEQIGRGAYGTAYLVHHKAERKRYVMKKIRLTKQNDKFQRTA 439 +KE + P + Y + IGRG +G Y + ++ +K + L ++ + A Sbjct: 3 SKEISIRSRTPPSKLYSIQSCIGRGNFGDVYKAVDRVTQEIVAIKVVNLEHSDEDIELLA 62 Query: 440 YQEMSLMASLSNPYIVEYKDGWVDEGTSVCIVTSYCEGGDMAQRIKK 580 QE+ +A L +P I Y +++ S+ IV YC GG + +K+ Sbjct: 63 -QEIFFLAELKSPLITNYIATMLED-VSMWIVMEYCGGGSCSDLLKR 107
>KAPCA_CANFA (Q8MJ44) cAMP-dependent protein kinase, alpha-catalytic subunit (EC| 2.7.11.11) (PKA C-alpha) Length = 349 Score = 46.2 bits (108), Expect = 7e-05 Identities = 30/116 (25%), Positives = 59/116 (50%), Gaps = 7/116 (6%) Frame = +2 Query: 254 ARAKEQELGKARNP------MEQYEVVEQIGRGAYGTAYLVHHKAERKRYVMKKIRLTKQ 415 A+AKE L K NP ++Q+E ++ +G G++G LV HK + MK + K Sbjct: 19 AKAKEDFLKKWENPAQNTAHLDQFERIKTLGTGSFGRVMLVKHKETGNHFAMKILDKQKV 78 Query: 416 NDKFQ-RTAYQEMSLMASLSNPYIVEYKDGWVDEGTSVCIVTSYCEGGDMAQRIKK 580 Q E ++ +++ P++V+ + + D +++ +V Y GG+M +++ Sbjct: 79 VKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKD-NSNLYMVMEYVPGGEMFSHLRR 133
>PKND_CHLTR (O84303) Serine/threonine-protein kinase pknD (EC 2.7.11.1)| Length = 934 Score = 46.2 bits (108), Expect = 7e-05 Identities = 29/95 (30%), Positives = 46/95 (48%), Gaps = 1/95 (1%) Frame = +2 Query: 296 MEQYEVVEQIGRGAYGTAYLVHHKAERKRYVMKKIRLTKQNDKFQRTAY-QEMSLMASLS 472 M++YE++ IG+G G YL H KA +R +K+IR + R + +E + A L Sbjct: 1 MQRYELIRLIGKGGMGEVYLAHDKACSRRVALKRIREDLSGNALLRQRFLREAKIAADLI 60 Query: 473 NPYIVEYKDGWVDEGTSVCIVTSYCEGGDMAQRIK 577 +P IV +G +V Y EG + +K Sbjct: 61 HPGIVPVY-SICSDGEAVYYTMPYIEGFSLKSLLK 94
>CDC2_DICDI (P34112) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) Length = 296 Score = 46.2 bits (108), Expect = 7e-05 Identities = 23/68 (33%), Positives = 39/68 (57%) Frame = +2 Query: 296 MEQYEVVEQIGRGAYGTAYLVHHKAERKRYVMKKIRLTKQNDKFQRTAYQEMSLMASLSN 475 + +Y+ +E++G G YG Y KA + +KKIRL ++D TA +E+SL+ + + Sbjct: 7 LSRYQKLEKLGEGTYGKVYKAKEKATGRMVALKKIRL--EDDGVPSTALREISLLKEVPH 64 Query: 476 PYIVEYKD 499 P +V D Sbjct: 65 PNVVSLFD 72
>CDC2C_DROME (P23573) Cell division control protein 2 cognate (EC 2.7.11.22) (EC| 2.7.11.23) Length = 314 Score = 46.2 bits (108), Expect = 7e-05 Identities = 24/83 (28%), Positives = 45/83 (54%) Frame = +2 Query: 296 MEQYEVVEQIGRGAYGTAYLVHHKAERKRYVMKKIRLTKQNDKFQRTAYQEMSLMASLSN 475 ++ ++ E+IG G YG Y + + +KKIRL + + TA +E+SL+ +L + Sbjct: 5 LDNFQRAEKIGEGTYGIVYKARSNSTGQDVALKKIRLEGETEGVPSTAIREISLLKNLKH 64 Query: 476 PYIVEYKDGWVDEGTSVCIVTSY 544 P +V+ D V G ++ ++ Y Sbjct: 65 PNVVQLFD-VVISGNNLYMIFEY 86
>GCN2_YEAST (P15442) Serine/threonine-protein kinase GCN2 (EC 2.7.11.1)| Length = 1590 Score = 46.2 bits (108), Expect = 7e-05 Identities = 22/70 (31%), Positives = 40/70 (57%) Frame = +2 Query: 305 YEVVEQIGRGAYGTAYLVHHKAERKRYVMKKIRLTKQNDKFQRTAYQEMSLMASLSNPYI 484 +E + +G+GA+G + + + Y +KKIR T++ T E+ L+ASL++ Y+ Sbjct: 530 FEEIAVLGQGAFGQVVKARNALDSRYYAIKKIRHTEEK---LSTILSEVMLLASLNHQYV 586 Query: 485 VEYKDGWVDE 514 V Y W++E Sbjct: 587 VRYYAAWLEE 596
>CDK7_XENLA (P20911) Cell division protein kinase 7 (EC 2.7.11.22) (EC| 2.7.11.23) (40 kDa protein kinase) (P40 MO15) (CDC2/CDK2,4-activating kinase) Length = 352 Score = 45.8 bits (107), Expect = 9e-05 Identities = 25/76 (32%), Positives = 41/76 (53%), Gaps = 3/76 (3%) Frame = +2 Query: 287 RNPMEQYEVVEQIGRGAYGTAYLVHHKAERKRYVMKKIRL---TKQNDKFQRTAYQEMSL 457 R+ +QYE ++ +G G + T Y K + +KKI+L + ND RTA +E+ L Sbjct: 12 RSRAKQYEKLDFLGEGQFATVYKARDKNTDRIVAIKKIKLGHRAEANDGINRTALREIKL 71 Query: 458 MASLSNPYIVEYKDGW 505 + LS+P I+ D + Sbjct: 72 LQELSHPNIIGLLDAF 87
>CDC2H_DICDI (P34117) CDC2-like serine/threonine-protein kinase CRP (EC| 2.7.11.22) (EC 2.7.11.23) Length = 292 Score = 45.8 bits (107), Expect = 9e-05 Identities = 22/68 (32%), Positives = 38/68 (55%) Frame = +2 Query: 296 MEQYEVVEQIGRGAYGTAYLVHHKAERKRYVMKKIRLTKQNDKFQRTAYQEMSLMASLSN 475 ME+Y +E++G G YG ++ + +K+IRL +++ TA +E+SL+ L + Sbjct: 1 MEKYSKIEKLGEGTYGIVNKAKNRETGEIVALKRIRLDSEDEGVPCTAIREISLLKELKH 60 Query: 476 PYIVEYKD 499 P IV D Sbjct: 61 PNIVRLHD 68
>KAPCA_MOUSE (P05132) cAMP-dependent protein kinase, alpha-catalytic subunit (EC| 2.7.11.11) (PKA C-alpha) Length = 350 Score = 45.8 bits (107), Expect = 9e-05 Identities = 33/133 (24%), Positives = 65/133 (48%), Gaps = 9/133 (6%) Frame = +2 Query: 209 AATASNSAPQD--EHARARAKEQELGKARNP------MEQYEVVEQIGRGAYGTAYLVHH 364 AA A + Q+ + A+AKE L K P ++Q++ ++ +G G++G LV H Sbjct: 3 AAAAKKGSEQESVKEFLAKAKEDFLKKWETPSQNTAQLDQFDRIKTLGTGSFGRVMLVKH 62 Query: 365 KAERKRYVMKKIRLTKQNDKFQ-RTAYQEMSLMASLSNPYIVEYKDGWVDEGTSVCIVTS 541 K Y MK + K Q E ++ +++ P++V+ + + D +++ +V Sbjct: 63 KESGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKD-NSNLYMVME 121 Query: 542 YCEGGDMAQRIKK 580 Y GG+M +++ Sbjct: 122 YVAGGEMFSHLRR 134
>SAPK9_ORYSA (Q75V57) Serine/threonine-protein kinase SAPK9 (EC 2.7.11.1)| (Osmotic stress/abscisic acid-activated protein kinase 9) Length = 361 Score = 45.8 bits (107), Expect = 9e-05 Identities = 27/92 (29%), Positives = 50/92 (54%) Frame = +2 Query: 299 EQYEVVEQIGRGAYGTAYLVHHKAERKRYVMKKIRLTKQNDKFQRTAYQEMSLMASLSNP 478 ++YE+V++IG G +G A L+ ++A +K I + +K +E+ SL +P Sbjct: 20 DRYELVKEIGSGNFGVARLMRNRASGDLVAVKYI---DRGEKIDENVQREIINHRSLRHP 76 Query: 479 YIVEYKDGWVDEGTSVCIVTSYCEGGDMAQRI 574 I+ +K+ + T + IV Y GG++ +RI Sbjct: 77 NIIRFKE-VILTPTHLAIVMEYASGGELFERI 107
>CDC21_MEDSA (P24923) Cell division control protein 2 homolog 1 (EC 2.7.11.22)| (EC 2.7.11.23) (Fragment) Length = 291 Score = 45.8 bits (107), Expect = 9e-05 Identities = 22/64 (34%), Positives = 36/64 (56%) Frame = +2 Query: 308 EVVEQIGRGAYGTAYLVHHKAERKRYVMKKIRLTKQNDKFQRTAYQEMSLMASLSNPYIV 487 E VE+IG G YG Y + + +KKIRL ++++ TA +E+SL+ + + IV Sbjct: 2 ENVEKIGEGTYGVVYKARDRVTNETIALKKIRLEQEDEGVPSTAIREISLLKEMQHRNIV 61 Query: 488 EYKD 499 +D Sbjct: 62 RLQD 65
>CDC2H_PLAFK (Q07785) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (PfPK5) Length = 288 Score = 45.4 bits (106), Expect = 1e-04 Identities = 23/68 (33%), Positives = 39/68 (57%) Frame = +2 Query: 296 MEQYEVVEQIGRGAYGTAYLVHHKAERKRYVMKKIRLTKQNDKFQRTAYQEMSLMASLSN 475 ME+Y +E+IG G YG Y + + + +KKIRL K+++ T +E+S++ L + Sbjct: 1 MEKYHGLEKIGEGTYGVVYKAQNNYG-ETFALKKIRLEKEDEGIPSTTIREISILKELKH 59 Query: 476 PYIVEYKD 499 IV+ D Sbjct: 60 SNIVKLYD 67
>CDC2H_PLAF7 (P61075) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) Length = 288 Score = 45.4 bits (106), Expect = 1e-04 Identities = 23/68 (33%), Positives = 39/68 (57%) Frame = +2 Query: 296 MEQYEVVEQIGRGAYGTAYLVHHKAERKRYVMKKIRLTKQNDKFQRTAYQEMSLMASLSN 475 ME+Y +E+IG G YG Y + + + +KKIRL K+++ T +E+S++ L + Sbjct: 1 MEKYHGLEKIGEGTYGVVYKAQNNYG-ETFALKKIRLEKEDEGIPSTTIREISILKELKH 59 Query: 476 PYIVEYKD 499 IV+ D Sbjct: 60 SNIVKLYD 67
>FIN1_SCHPO (O13839) G2-specific protein kinase fin1 (EC 2.7.11.1)| Length = 722 Score = 45.4 bits (106), Expect = 1e-04 Identities = 25/96 (26%), Positives = 49/96 (51%), Gaps = 1/96 (1%) Frame = +2 Query: 296 MEQYEVVEQIGRGAYGTAYLVHHKAERKRYVMKKIRLTKQNDKFQRTAYQEMSLMASLSN 475 ME+Y+++E IG G++G Y V + K+I + ++ E++++ +L + Sbjct: 1 MEKYKILECIGHGSFGRIYKVQRLKDGALLAQKEIHFGNITRQEKQYIADEVNILRNLKH 60 Query: 476 PYIVEYKDGWVDEGTSVC-IVTSYCEGGDMAQRIKK 580 P IV+Y ++ V + YC GD+A I++ Sbjct: 61 PNIVQYCGEELNRSAQVINLYMEYCGHGDLANLIQR 96
>CTK1_YEAST (Q03957) CTD kinase subunit alpha (EC 2.7.11.23) (CTD kinase 58 kDa| subunit) (CTDK-I alpha subunit) Length = 528 Score = 45.4 bits (106), Expect = 1e-04 Identities = 22/82 (26%), Positives = 41/82 (50%) Frame = +2 Query: 305 YEVVEQIGRGAYGTAYLVHHKAERKRYVMKKIRLTKQNDKFQRTAYQEMSLMASLSNPYI 484 Y + Q+G G YG Y + K +KK+RL + + F T+ +E+ L+ S +P + Sbjct: 183 YLRIMQVGEGTYGKVYKAKNTNTEKLVALKKLRLQGEREGFPITSIREIKLLQSFDHPNV 242 Query: 485 VEYKDGWVDEGTSVCIVTSYCE 550 K+ V+ +V ++ Y + Sbjct: 243 STIKEIMVESQKTVYMIFEYAD 264
>KCC4_RAT (P13234) Calcium/calmodulin-dependent protein kinase type IV (EC| 2.7.11.17) (CAM kinase-GR) (CaMK IV) (Calspermin) Length = 474 Score = 45.4 bits (106), Expect = 1e-04 Identities = 30/100 (30%), Positives = 53/100 (53%), Gaps = 1/100 (1%) Frame = +2 Query: 278 GKARNPMEQY-EVVEQIGRGAYGTAYLVHHKAERKRYVMKKIRLTKQNDKFQRTAYQEMS 454 G R+P+ + EV ++GRGA Y K +K Y +K ++ T + K RT E+ Sbjct: 32 GSKRDPLSDFFEVESELGRGATSIVYRCKQKGTQKPYALKVLKKT-VDKKIVRT---EIG 87 Query: 455 LMASLSNPYIVEYKDGWVDEGTSVCIVTSYCEGGDMAQRI 574 ++ LS+P I++ K+ + + T + +V GG++ RI Sbjct: 88 VLLRLSHPNIIKLKEIF-ETPTEISLVLELVTGGELFDRI 126
>CDC15_YEAST (P27636) Cell division control protein 15 (EC 2.7.11.1)| Length = 974 Score = 45.4 bits (106), Expect = 1e-04 Identities = 27/100 (27%), Positives = 52/100 (52%) Frame = +2 Query: 281 KARNPMEQYEVVEQIGRGAYGTAYLVHHKAERKRYVMKKIRLTKQNDKFQRTAYQEMSLM 460 +A QY + + IGRG+YG Y +K + +K++ +ND+ E+SL+ Sbjct: 17 RASEKSVQYHLKQVIGRGSYGVVYKAINKHTDQVVAIKEV--VYENDEELNDIMAEISLL 74 Query: 461 ASLSNPYIVEYKDGWVDEGTSVCIVTSYCEGGDMAQRIKK 580 +L++ IV+Y G++ + + I+ YC G + + I + Sbjct: 75 KNLNHNNIVKY-HGFIRKSYELYILLEYCANGSLRRLISR 113
>KCC2_SCHPO (O42844) Calcium/calmodulin-dependent protein kinase type II (EC| 2.7.11.17) (CAM kinase II) Length = 504 Score = 45.1 bits (105), Expect = 1e-04 Identities = 25/104 (24%), Positives = 56/104 (53%), Gaps = 1/104 (0%) Frame = +2 Query: 266 EQELGKARNP-MEQYEVVEQIGRGAYGTAYLVHHKAERKRYVMKKIRLTKQNDKFQRTAY 442 ++E+ A P +E+Y+++E +G GA+ Y + ++ +K IR + N K ++ + Sbjct: 51 DEEIRVANYPGLEKYQLIENLGDGAFSQVYKAYSIDRKEHVAVKVIRKYEMNKKQRQGVF 110 Query: 443 QEMSLMASLSNPYIVEYKDGWVDEGTSVCIVTSYCEGGDMAQRI 574 +E+++M + + +V D +V+ +V EGG++ +I Sbjct: 111 KEVNIMRRVKHKNVVNLFD-FVETEDFYHLVMELAEGGELFHQI 153
>TLK2_MOUSE (O55047) Serine/threonine-protein kinase tousled-like 2 (EC| 2.7.11.1) (Tousled-like kinase 2) Length = 718 Score = 45.1 bits (105), Expect = 1e-04 Identities = 28/100 (28%), Positives = 48/100 (48%), Gaps = 6/100 (6%) Frame = +2 Query: 299 EQYEVVEQIGRGAYGTAYLVHHKAERKRYVMKKIRLTKQN------DKFQRTAYQEMSLM 460 ++Y ++ +GRG + Y E+ RYV KI +N + + + A +E + Sbjct: 406 DRYLLLHLLGRGGFSEVYKAFDLTEQ-RYVAVKIHQLNKNWRDEKKENYHKHACREYRIH 464 Query: 461 ASLSNPYIVEYKDGWVDEGTSVCIVTSYCEGGDMAQRIKK 580 L +P IV+ D + + S C V YCEG D+ +K+ Sbjct: 465 KELDHPRIVKLYDYFSLDTDSFCTVLEYCEGNDLDFYLKQ 504
>TLK2_HUMAN (Q86UE8) Serine/threonine-protein kinase tousled-like 2 (EC| 2.7.11.1) (Tousled-like kinase 2) (PKU-alpha) Length = 772 Score = 45.1 bits (105), Expect = 1e-04 Identities = 28/100 (28%), Positives = 48/100 (48%), Gaps = 6/100 (6%) Frame = +2 Query: 299 EQYEVVEQIGRGAYGTAYLVHHKAERKRYVMKKIRLTKQN------DKFQRTAYQEMSLM 460 ++Y ++ +GRG + Y E+ RYV KI +N + + + A +E + Sbjct: 460 DRYLLLHLLGRGGFSEVYKAFDLTEQ-RYVAVKIHQLNKNWRDEKKENYHKHACREYRIH 518 Query: 461 ASLSNPYIVEYKDGWVDEGTSVCIVTSYCEGGDMAQRIKK 580 L +P IV+ D + + S C V YCEG D+ +K+ Sbjct: 519 KELDHPRIVKLYDYFSLDTDSFCTVLEYCEGNDLDFYLKQ 558
>COT1_NEUCR (P38679) Serine/threonine-protein kinase cot-1 (EC 2.7.11.1)| (Colonial temperature-sensitive 1) Length = 598 Score = 45.1 bits (105), Expect = 1e-04 Identities = 27/101 (26%), Positives = 52/101 (51%), Gaps = 1/101 (0%) Frame = +2 Query: 281 KARNPMEQYEVVEQIGRGAYGTAYLVHHKAERKRYVMKKIRLTKQNDKFQRTAYQ-EMSL 457 + ++ E Y+ ++ IG+GA+G LV KA+ K Y MK + T+ K Q + E + Sbjct: 206 RTKDKPENYQTIKIIGKGAFGEVKLVQKKADGKVYAMKSLIKTEMFKKDQLAHVRAERDI 265 Query: 458 MASLSNPYIVEYKDGWVDEGTSVCIVTSYCEGGDMAQRIKK 580 +A +P++V+ + D + ++ + GGD+ + K Sbjct: 266 LAESDSPWVVKLYTTFQD-ANFLYMLMEFLPGGDLMTMLIK 305
>CDC2_CAEEL (P34556) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) Length = 332 Score = 45.1 bits (105), Expect = 1e-04 Identities = 21/64 (32%), Positives = 35/64 (54%) Frame = +2 Query: 296 MEQYEVVEQIGRGAYGTAYLVHHKAERKRYVMKKIRLTKQNDKFQRTAYQEMSLMASLSN 475 + + +E+IG G YG Y ++ MKKIRL +++ TA +E+SL+ L + Sbjct: 19 LNDFTKLEKIGEGTYGVVYKGKNRRTNAMVAMKKIRLESEDEGVPSTAVREISLLKELQH 78 Query: 476 PYIV 487 P +V Sbjct: 79 PNVV 82
>WIS1_SCHPO (P33886) Protein kinase wis1 (EC 2.7.12.2) (Protein kinase sty2)| Length = 605 Score = 45.1 bits (105), Expect = 1e-04 Identities = 26/89 (29%), Positives = 45/89 (50%) Frame = +2 Query: 296 MEQYEVVEQIGRGAYGTAYLVHHKAERKRYVMKKIRLTKQNDKFQRTAYQEMSLMASLSN 475 M + +E++G+G YG Y H+ +K+IRL+ + F + E+ ++ + Sbjct: 317 MSEIIKLEELGKGNYGVVYKALHQPTGVTMALKEIRLSLEEATFNQ-IIMELDILHKAVS 375 Query: 476 PYIVEYKDGWVDEGTSVCIVTSYCEGGDM 562 PYIV++ + EG SV I Y + G M Sbjct: 376 PYIVDFYGAFFVEG-SVFICMEYMDAGSM 403
>LIMK2_RAT (P53670) LIM domain kinase 2 (EC 2.7.11.1) (LIMK-2)| Length = 638 Score = 45.1 bits (105), Expect = 1e-04 Identities = 27/82 (32%), Positives = 49/82 (59%) Frame = +2 Query: 317 EQIGRGAYGTAYLVHHKAERKRYVMKKIRLTKQNDKFQRTAYQEMSLMASLSNPYIVEYK 496 E +G+G +G A V HKA K VMK+ L + +++ Q+T E+ +M SL +P ++++ Sbjct: 335 EVLGKGFFGQAIKVTHKATGKVMVMKE--LIRCDEETQKTFLTEVKVMRSLDHPNVLKF- 391 Query: 497 DGWVDEGTSVCIVTSYCEGGDM 562 G + + + ++T Y EGG + Sbjct: 392 IGVLYKDKKLNLLTEYIEGGTL 413
>LIMK2_MOUSE (O54785) LIM domain kinase 2 (EC 2.7.11.1) (LIMK-2)| Length = 638 Score = 45.1 bits (105), Expect = 1e-04 Identities = 27/82 (32%), Positives = 49/82 (59%) Frame = +2 Query: 317 EQIGRGAYGTAYLVHHKAERKRYVMKKIRLTKQNDKFQRTAYQEMSLMASLSNPYIVEYK 496 E +G+G +G A V HKA K VMK+ L + +++ Q+T E+ +M SL +P ++++ Sbjct: 335 EVLGKGFFGQAIKVTHKATGKVMVMKE--LIRCDEETQKTFLTEVKVMRSLDHPNVLKF- 391 Query: 497 DGWVDEGTSVCIVTSYCEGGDM 562 G + + + ++T Y EGG + Sbjct: 392 IGVLYKDKKLNLLTEYIEGGTL 413
>LIMK2_HUMAN (P53671) LIM domain kinase 2 (EC 2.7.11.1) (LIMK-2)| Length = 638 Score = 45.1 bits (105), Expect = 1e-04 Identities = 27/82 (32%), Positives = 49/82 (59%) Frame = +2 Query: 317 EQIGRGAYGTAYLVHHKAERKRYVMKKIRLTKQNDKFQRTAYQEMSLMASLSNPYIVEYK 496 E +G+G +G A V HKA K VMK+ L + +++ Q+T E+ +M SL +P ++++ Sbjct: 335 EVLGKGFFGQAIKVTHKATGKVMVMKE--LIRCDEETQKTFLTEVKVMRSLDHPNVLKF- 391 Query: 497 DGWVDEGTSVCIVTSYCEGGDM 562 G + + + ++T Y EGG + Sbjct: 392 IGVLYKDKKLNLLTEYIEGGTL 413
>LIMK2_CHICK (P53666) LIM domain kinase 2 (EC 2.7.11.1) (LIMK-2)| Length = 642 Score = 45.1 bits (105), Expect = 1e-04 Identities = 27/82 (32%), Positives = 49/82 (59%) Frame = +2 Query: 317 EQIGRGAYGTAYLVHHKAERKRYVMKKIRLTKQNDKFQRTAYQEMSLMASLSNPYIVEYK 496 E +G+G +G A V HKA K VMK+ L + +++ Q+T E+ +M SL +P ++++ Sbjct: 335 EVLGKGFFGQAIKVTHKATGKVMVMKE--LIRCDEETQKTFLTEVKVMRSLDHPNVLKF- 391 Query: 497 DGWVDEGTSVCIVTSYCEGGDM 562 G + + + ++T Y EGG + Sbjct: 392 IGVLYKDKKLNLLTEYIEGGTL 413
>KS6AA_XENLA (P10665) Ribosomal protein S6 kinase 2 alpha (EC 2.7.11.1)| (Ribosomal protein S6 kinase II alpha) (S6KII-alpha) (P90-RSK) (MAP kinase-activated protein kinase 1) (MAPK-activated protein kinase 1) (MAPKAP kinase 1) (MAPKAPK-1) Length = 733 Score = 44.7 bits (104), Expect = 2e-04 Identities = 30/94 (31%), Positives = 45/94 (47%), Gaps = 1/94 (1%) Frame = +2 Query: 296 MEQYEVVEQIGRGAYGTAYLVHHKAERKRYVMKKIRLTKQNDKFQRTAYQEMSLMASL-S 472 M+ Y V E IG G+Y HK Y +K I DK +R +E+ ++ Sbjct: 413 MDVYTVRETIGVGSYSVCKRCVHKGTNMEYAVKVI------DKTKRDPSEEIEILRRYGQ 466 Query: 473 NPYIVEYKDGWVDEGTSVCIVTSYCEGGDMAQRI 574 +P I+ KD + EG S+ +VT GG++ RI Sbjct: 467 HPNIIALKDVY-KEGNSIYVVTELMRGGELLDRI 499
>KCC4_MOUSE (P08414) Calcium/calmodulin-dependent protein kinase type IV (EC| 2.7.11.17) (CAM kinase-GR) (CaMK IV) Length = 469 Score = 44.7 bits (104), Expect = 2e-04 Identities = 30/100 (30%), Positives = 54/100 (54%), Gaps = 1/100 (1%) Frame = +2 Query: 278 GKARNPM-EQYEVVEQIGRGAYGTAYLVHHKAERKRYVMKKIRLTKQNDKFQRTAYQEMS 454 G R+P+ + +EV ++GRGA Y K +K Y +K ++ T + K RT E+ Sbjct: 32 GSNRDPLGDFFEVESELGRGATSIVYRCKQKGTQKPYALKVLKKT-VDKKIVRT---EIG 87 Query: 455 LMASLSNPYIVEYKDGWVDEGTSVCIVTSYCEGGDMAQRI 574 ++ LS+P I++ K+ + + T + +V GG++ RI Sbjct: 88 VLLRLSHPNIIKLKEIF-ETPTEISLVLELVTGGELFDRI 126
>NRKA_TRYBB (Q08942) Putative serine/threonine-protein kinase A (EC 2.7.11.1)| Length = 431 Score = 44.7 bits (104), Expect = 2e-04 Identities = 23/85 (27%), Positives = 47/85 (55%) Frame = +2 Query: 323 IGRGAYGTAYLVHHKAERKRYVMKKIRLTKQNDKFQRTAYQEMSLMASLSNPYIVEYKDG 502 +G G+YG AY+ + V K + L+K + + +R A E+ +A+ ++P I+ Y + Sbjct: 26 VGLGSYGEAYVAESVEDGSLCVAKVMDLSKMSQRDKRYAQSEIKCLANCNHPNIIRYIED 85 Query: 503 WVDEGTSVCIVTSYCEGGDMAQRIK 577 +E + IV + + G++ ++IK Sbjct: 86 H-EENDRLLIVMEFADSGNLDEQIK 109
>CDK5_RAT (Q03114) Cell division protein kinase 5 (EC 2.7.11.22) (Tau protein| kinase II catalytic subunit) (TPKII catalytic subunit) (Serine/threonine-protein kinase PSSALRE) Length = 292 Score = 44.7 bits (104), Expect = 2e-04 Identities = 22/85 (25%), Positives = 45/85 (52%) Frame = +2 Query: 296 MEQYEVVEQIGRGAYGTAYLVHHKAERKRYVMKKIRLTKQNDKFQRTAYQEMSLMASLSN 475 M++YE +E+IG G YGT + ++ + +K++RL ++ +A +E+ L+ L + Sbjct: 1 MQKYEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELKH 60 Query: 476 PYIVEYKDGWVDEGTSVCIVTSYCE 550 IV D + + +V +C+ Sbjct: 61 KNIVRLHD-VLHSDKKLTLVFEFCD 84
>CDK5_MOUSE (P49615) Cell division protein kinase 5 (EC 2.7.11.22) (Tau protein| kinase II catalytic subunit) (TPKII catalytic subunit) (Serine/threonine-protein kinase PSSALRE) (CRK6) Length = 292 Score = 44.7 bits (104), Expect = 2e-04 Identities = 22/85 (25%), Positives = 45/85 (52%) Frame = +2 Query: 296 MEQYEVVEQIGRGAYGTAYLVHHKAERKRYVMKKIRLTKQNDKFQRTAYQEMSLMASLSN 475 M++YE +E+IG G YGT + ++ + +K++RL ++ +A +E+ L+ L + Sbjct: 1 MQKYEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELKH 60 Query: 476 PYIVEYKDGWVDEGTSVCIVTSYCE 550 IV D + + +V +C+ Sbjct: 61 KNIVRLHD-VLHSDKKLTLVFEFCD 84
>CDK5_HUMAN (Q00535) Cell division protein kinase 5 (EC 2.7.11.22) (Tau protein| kinase II catalytic subunit) (TPKII catalytic subunit) (Serine/threonine-protein kinase PSSALRE) Length = 292 Score = 44.7 bits (104), Expect = 2e-04 Identities = 22/85 (25%), Positives = 45/85 (52%) Frame = +2 Query: 296 MEQYEVVEQIGRGAYGTAYLVHHKAERKRYVMKKIRLTKQNDKFQRTAYQEMSLMASLSN 475 M++YE +E+IG G YGT + ++ + +K++RL ++ +A +E+ L+ L + Sbjct: 1 MQKYEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELKH 60 Query: 476 PYIVEYKDGWVDEGTSVCIVTSYCE 550 IV D + + +V +C+ Sbjct: 61 KNIVRLHD-VLHSDKKLTLVFEFCD 84
>CDK5_BOVIN (Q02399) Cell division protein kinase 5 (EC 2.7.11.22) (Tau protein| kinase II catalytic subunit) (TPKII catalytic subunit) (Proline-directed protein kinase 33 kDa subunit) (PDPK) Length = 292 Score = 44.7 bits (104), Expect = 2e-04 Identities = 22/85 (25%), Positives = 45/85 (52%) Frame = +2 Query: 296 MEQYEVVEQIGRGAYGTAYLVHHKAERKRYVMKKIRLTKQNDKFQRTAYQEMSLMASLSN 475 M++YE +E+IG G YGT + ++ + +K++RL ++ +A +E+ L+ L + Sbjct: 1 MQKYEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELKH 60 Query: 476 PYIVEYKDGWVDEGTSVCIVTSYCE 550 IV D + + +V +C+ Sbjct: 61 KNIVRLHD-VLHSDKKLTLVFEFCD 84
>KAPCA_CRIGR (P25321) cAMP-dependent protein kinase, alpha-catalytic subunit (EC| 2.7.11.11) (PKA C-alpha) Length = 350 Score = 44.7 bits (104), Expect = 2e-04 Identities = 32/133 (24%), Positives = 66/133 (49%), Gaps = 9/133 (6%) Frame = +2 Query: 209 AATASNSAPQD--EHARARAKEQELGKARNP------MEQYEVVEQIGRGAYGTAYLVHH 364 AA A + Q+ + A+AKE+ L K +P ++ ++ ++ +G G++G LV H Sbjct: 3 AAAAKKGSEQESVKEFLAKAKEEFLKKWESPSQNTAQLDHFDRIKTLGTGSFGRVMLVKH 62 Query: 365 KAERKRYVMKKIRLTKQNDKFQ-RTAYQEMSLMASLSNPYIVEYKDGWVDEGTSVCIVTS 541 K Y MK + K Q E ++ +++ P++V+ + + D +++ +V Sbjct: 63 KETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKD-NSNLYMVME 121 Query: 542 YCEGGDMAQRIKK 580 Y GG+M +++ Sbjct: 122 YVPGGEMFSHLRR 134
>KAD5_SCHPO (Q09831) Probable serine/threonine-protein kinase C4G8.05 (EC| 2.7.11.1) Length = 566 Score = 44.7 bits (104), Expect = 2e-04 Identities = 30/96 (31%), Positives = 50/96 (52%), Gaps = 4/96 (4%) Frame = +2 Query: 305 YEVVEQIGRGAYGTAYLVHHKAERKRYVMK---KIRLTKQNDKFQRTAYQEMSLMASLSN 475 +E V +G+G G YLV K K Y MK K + K+N + A+ E ++A+ ++ Sbjct: 195 FEKVFLLGKGDVGRVYLVREKKSGKFYAMKVLSKQEMIKRNK--SKRAFAEQHILATSNH 252 Query: 476 PYIVE-YKDGWVDEGTSVCIVTSYCEGGDMAQRIKK 580 P+IV Y DE +C+ YC GG+ + +++ Sbjct: 253 PFIVTLYHSFQSDEYLYLCM--EYCMGGEFFRALQR 286
>CBK1_YARLI (Q6CFS5) Serine/threonine-protein kinase CBK1 (EC 2.7.11.1)| Length = 588 Score = 44.3 bits (103), Expect = 3e-04 Identities = 37/147 (25%), Positives = 66/147 (44%), Gaps = 2/147 (1%) Frame = +2 Query: 146 HQRRALPVSSPEHHRIIYTRPAATASNSAPQDEHARARAKEQELGKARNPMEQYEVVEQI 325 HQRR+ +S E R + + + R R + R +E + V+ I Sbjct: 161 HQRRSAAEASVEQATSEERRNRVLTNYGKKETAYLRMR-------RTRMALEDFVTVKVI 213 Query: 326 GRGAYGTAYLVHHKAERKRYVMKKIRLTKQNDKFQRTAY--QEMSLMASLSNPYIVEYKD 499 G+GA+G LV + K Y MK + L K+ D ++ A+ E ++A +P+IV Sbjct: 214 GKGAFGEVRLVQKRDNGKIYAMKTM-LKKEMDMKEQWAHVKAERDVLADSDSPWIVSLYF 272 Query: 500 GWVDEGTSVCIVTSYCEGGDMAQRIKK 580 + D+ + ++ + GGD+ + K Sbjct: 273 SFQDD-LYLYLIMEFLPGGDLMTMLIK 298
>ST32A_MOUSE (Q8BGW6) Serine/threonine-protein kinase 32A (EC 2.7.11.1)| Length = 398 Score = 44.3 bits (103), Expect = 3e-04 Identities = 23/95 (24%), Positives = 50/95 (52%), Gaps = 1/95 (1%) Frame = +2 Query: 299 EQYEVVEQIGRGAYGTAYLVHHKAERKRYVMKKIRLTKQNDKFQ-RTAYQEMSLMASLSN 475 + +E++ IG+G++G +V +K Y MK + K ++ + R ++E+ +M L + Sbjct: 21 DHFEILRAIGKGSFGKVCIVRKNDTKKMYAMKYMNKQKCVERNEVRNVFKELQIMQGLEH 80 Query: 476 PYIVEYKDGWVDEGTSVCIVTSYCEGGDMAQRIKK 580 P++V + DE + +V GGD+ +++ Sbjct: 81 PFLVNLWYSFQDE-EDMFMVVDLLLGGDLRYHLQQ 114
>CDC2C_ANTMA (Q38774) Cell division control protein 2 homolog C (EC 2.7.11.22)| (EC 2.7.11.23) Length = 305 Score = 44.3 bits (103), Expect = 3e-04 Identities = 23/64 (35%), Positives = 34/64 (53%) Frame = +2 Query: 296 MEQYEVVEQIGRGAYGTAYLVHHKAERKRYVMKKIRLTKQNDKFQRTAYQEMSLMASLSN 475 ME+YE +E++G G YG Y K+ + +KK RL + TA +E+SL+ LS Sbjct: 1 MEKYEKLEKVGEGTYGKVYKALEKSTGQVVALKKTRLEMDEEGVPPTALREVSLLQMLSQ 60 Query: 476 PYIV 487 V Sbjct: 61 SLYV 64
>ST38L_HUMAN (Q9Y2H1) Serine/threonine-protein kinase 38-like (EC 2.7.11.1)| (NDR2 protein kinase) (Nuclear Dbf2-related kinase 2) Length = 464 Score = 44.3 bits (103), Expect = 3e-04 Identities = 29/116 (25%), Positives = 56/116 (48%), Gaps = 1/116 (0%) Frame = +2 Query: 236 QDEHARARAKEQELGKARNPMEQYEVVEQIGRGAYGTAYLVHHKAERKRYVMKKIRLTKQ 415 + +HAR + L + R ++ +E ++ IGRGA+G LV K Y MK +R + Sbjct: 67 RSQHARKETEFLRLKRTRLGLDDFESLKVIGRGAFGEVRLVQKKDTGHIYAMKILRKSDM 126 Query: 416 NDKFQRTAYQ-EMSLMASLSNPYIVEYKDGWVDEGTSVCIVTSYCEGGDMAQRIKK 580 +K Q + E ++ ++V+ + D+ ++ ++ + GGDM + K Sbjct: 127 LEKEQVAHIRAERDILVEADGAWVVKMFYSFQDK-RNLYLIMEFLPGGDMMTLLMK 181
>ST32A_HUMAN (Q8WU08) Serine/threonine-protein kinase 32A (EC 2.7.11.1) (YANK1)| Length = 396 Score = 44.3 bits (103), Expect = 3e-04 Identities = 23/95 (24%), Positives = 50/95 (52%), Gaps = 1/95 (1%) Frame = +2 Query: 299 EQYEVVEQIGRGAYGTAYLVHHKAERKRYVMKKIRLTKQNDKFQ-RTAYQEMSLMASLSN 475 + +E++ IG+G++G +V +K Y MK + K ++ + R ++E+ +M L + Sbjct: 21 DHFEILRAIGKGSFGKVCIVQKNDTKKMYAMKYMNKQKCVERNEVRNVFKELQIMQGLEH 80 Query: 476 PYIVEYKDGWVDEGTSVCIVTSYCEGGDMAQRIKK 580 P++V + DE + +V GGD+ +++ Sbjct: 81 PFLVNLWYSFQDE-EDMFMVVDLLLGGDLRYHLQQ 114
>CDC2H_THEPA (Q27032) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) Length = 298 Score = 44.3 bits (103), Expect = 3e-04 Identities = 23/68 (33%), Positives = 39/68 (57%) Frame = +2 Query: 296 MEQYEVVEQIGRGAYGTAYLVHHKAERKRYVMKKIRLTKQNDKFQRTAYQEMSLMASLSN 475 M +Y +E+IG G YG Y + + +KKIR+ ++++ TA +E+SL+ L + Sbjct: 1 MRRYHKMEKIGEGTYGVVYKAQNN-HGEICALKKIRVEEEDEGIPSTAIREISLLKELHH 59 Query: 476 PYIVEYKD 499 P IV +D Sbjct: 60 PNIVWLRD 67
>CDC2H_THEAN (Q26671) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) Length = 298 Score = 44.3 bits (103), Expect = 3e-04 Identities = 23/68 (33%), Positives = 39/68 (57%) Frame = +2 Query: 296 MEQYEVVEQIGRGAYGTAYLVHHKAERKRYVMKKIRLTKQNDKFQRTAYQEMSLMASLSN 475 M +Y +E+IG G YG Y + + +KKIR+ ++++ TA +E+SL+ L + Sbjct: 1 MRRYHKMEKIGEGTYGVVYKAQNN-HGEICALKKIRVEEEDEGIPSTAIREISLLKELHH 59 Query: 476 PYIVEYKD 499 P IV +D Sbjct: 60 PNIVWLRD 67
>CDK5_XENLA (P51166) Cell division protein kinase 5 (EC 2.7.11.22) (Neuronal| cyclin-dependent kinase 5) Length = 292 Score = 44.3 bits (103), Expect = 3e-04 Identities = 22/85 (25%), Positives = 45/85 (52%) Frame = +2 Query: 296 MEQYEVVEQIGRGAYGTAYLVHHKAERKRYVMKKIRLTKQNDKFQRTAYQEMSLMASLSN 475 M++YE +E+IG G YGT + ++ + +K++RL ++ +A +E+ L+ L + Sbjct: 1 MQKYEKLEKIGEGTYGTVFKAKNRDTHEIVALKRVRLDDDDEGVPSSALREICLLKELKH 60 Query: 476 PYIVEYKDGWVDEGTSVCIVTSYCE 550 IV D + + +V +C+ Sbjct: 61 KNIVRLHD-VLHSDKKLTLVFEFCD 84
>KAPCA_RAT (P27791) cAMP-dependent protein kinase, alpha-catalytic subunit (EC| 2.7.11.11) (PKA C-alpha) Length = 350 Score = 44.3 bits (103), Expect = 3e-04 Identities = 32/133 (24%), Positives = 65/133 (48%), Gaps = 9/133 (6%) Frame = +2 Query: 209 AATASNSAPQD--EHARARAKEQELGKARNP------MEQYEVVEQIGRGAYGTAYLVHH 364 AA A + Q+ + A+AKE L K +P ++ ++ ++ +G G++G LV H Sbjct: 3 AAAAKKGSEQESVKEFLAKAKEDFLKKWEDPSQNTAQLDHFDRIKTLGTGSFGRVMLVKH 62 Query: 365 KAERKRYVMKKIRLTKQNDKFQ-RTAYQEMSLMASLSNPYIVEYKDGWVDEGTSVCIVTS 541 K Y MK + K Q E ++ +++ P++V+ + + D +++ +V Sbjct: 63 KESGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKD-NSNLYMVME 121 Query: 542 YCEGGDMAQRIKK 580 Y GG+M +++ Sbjct: 122 YVPGGEMFSHLRR 134
>CBK1_CANGA (Q6FP74) Serine/threonine-protein kinase CBK1 (EC 2.7.11.1)| Length = 773 Score = 44.3 bits (103), Expect = 3e-04 Identities = 42/172 (24%), Positives = 76/172 (44%), Gaps = 8/172 (4%) Frame = +2 Query: 71 RRPLLSHFHTRAAAVHARSPLRDHHHQRRALPVSSPEHHRIIYTRPAATASNSAPQDEHA 250 RRP L T+ A + + +++ Q + E + T S++ ++ +A Sbjct: 288 RRPDLLSKSTQDKAAAVKLKVENYYQQSVKYAIERNERRVELETE---LGSHNWSEERNA 344 Query: 251 RARA----KEQE---LGKARNPMEQYEVVEQIGRGAYGTAYLVHHKAERKRYVMKKIRLT 409 R A KE + L + R +E + V+ IG+GA+G LV K K Y MK + + Sbjct: 345 RQLASLGKKESQFLRLRRTRLSLEDFHTVQVIGKGAFGEVRLVQKKDTGKIYAMKTLLKS 404 Query: 410 KQNDKFQRTAYQ-EMSLMASLSNPYIVEYKDGWVDEGTSVCIVTSYCEGGDM 562 + K Q + E ++A +P+IV + D + ++ + GGD+ Sbjct: 405 EMYKKDQLAHVKAERDVLAGTDSPWIVSLYYSFQD-AQYLYLIMEFLPGGDL 455
>ST32B_MOUSE (Q9JJX8) Serine/threonine-protein kinase 32B (EC 2.7.11.1)| Length = 414 Score = 43.9 bits (102), Expect = 3e-04 Identities = 22/95 (23%), Positives = 51/95 (53%), Gaps = 1/95 (1%) Frame = +2 Query: 299 EQYEVVEQIGRGAYGTAYLVHHKAERKRYVMKKIRLTKQNDKFQ-RTAYQEMSLMASLSN 475 + ++++ IG+G++G +V + +K Y MK + K ++ + R ++E+ +M L + Sbjct: 21 DHFQILRAIGKGSFGKVCIVQKRDTKKMYAMKYMNKQKCVERDEVRNVFRELQIMQGLEH 80 Query: 476 PYIVEYKDGWVDEGTSVCIVTSYCEGGDMAQRIKK 580 P++V + DE + +V GGD+ +++ Sbjct: 81 PFLVNLWYSFQDE-EDMFMVVDLLLGGDLRYHLQQ 114
>ST32B_HUMAN (Q9NY57) Serine/threonine-protein kinase 32B (EC 2.7.11.1) (YANK2)| Length = 414 Score = 43.9 bits (102), Expect = 3e-04 Identities = 22/95 (23%), Positives = 51/95 (53%), Gaps = 1/95 (1%) Frame = +2 Query: 299 EQYEVVEQIGRGAYGTAYLVHHKAERKRYVMKKIRLTKQNDKFQ-RTAYQEMSLMASLSN 475 + ++++ IG+G++G +V + +K Y MK + K ++ + R ++E+ +M L + Sbjct: 21 DHFQILRAIGKGSFGKVCIVQKRDTKKMYAMKYMNKQKCIERDEVRNVFRELQIMQGLEH 80 Query: 476 PYIVEYKDGWVDEGTSVCIVTSYCEGGDMAQRIKK 580 P++V + DE + +V GGD+ +++ Sbjct: 81 PFLVNLWYSFQDE-EDMFMVVDLLLGGDLRYHLQQ 114
>LIMK1_XENLA (O42565) LIM domain kinase 1 (EC 2.7.11.1) (LIMK-1) (xLIMK1)| Length = 615 Score = 43.9 bits (102), Expect = 3e-04 Identities = 26/87 (29%), Positives = 50/87 (57%) Frame = +2 Query: 317 EQIGRGAYGTAYLVHHKAERKRYVMKKIRLTKQNDKFQRTAYQEMSLMASLSNPYIVEYK 496 E +GRG +G A V H+ + VMK+ L + +++ QRT +E+ +M L +P+++++ Sbjct: 318 EVLGRGCFGQAIKVTHRVTGEVMVMKE--LIRFDEETQRTFLKEVKVMRCLEHPHVLKF- 374 Query: 497 DGWVDEGTSVCIVTSYCEGGDMAQRIK 577 G + + + +T Y GG + + IK Sbjct: 375 IGVLYKDKRLNFITEYIPGGTLRRVIK 401
>KS6A3_MOUSE (P18654) Ribosomal protein S6 kinase alpha-3 (EC 2.7.11.1)| (S6K-alpha 3) (90 kDa ribosomal protein S6 kinase 3) (p90-RSK 3) (Ribosomal S6 kinase 2) (RSK-2) (pp90RSK2) (MAP kinase-activated protein kinase 1b) (MAPKAPK1B) Length = 740 Score = 43.9 bits (102), Expect = 3e-04 Identities = 29/91 (31%), Positives = 46/91 (50%), Gaps = 1/91 (1%) Frame = +2 Query: 305 YEVVEQIGRGAYGTAYLVHHKAERKRYVMKKIRLTKQNDKFQRTAYQEMSLMASL-SNPY 481 YEV E IG G+Y HKA + +K I DK +R +E+ ++ +P Sbjct: 422 YEVKEDIGVGSYSVCKRCIHKATNMEFAVKII------DKSKRDPTEEIEILLRYGQHPN 475 Query: 482 IVEYKDGWVDEGTSVCIVTSYCEGGDMAQRI 574 I+ KD + D+G V +VT +GG++ +I Sbjct: 476 IITLKDVY-DDGKYVYVVTELMKGGELLDKI 505 Score = 41.6 bits (96), Expect = 0.002 Identities = 23/104 (22%), Positives = 52/104 (50%), Gaps = 3/104 (2%) Frame = +2 Query: 278 GKARNPMEQYEVVEQIGRGAYGTAYLVHH---KAERKRYVMKKIRLTKQNDKFQRTAYQE 448 G + Q+E+++ +G+G++G +LV R+ Y MK ++ + + E Sbjct: 59 GHEKADPSQFELLKVLGQGSFGKVFLVKKISGSDARQLYAMKVLKKATLKVRDRVRTKME 118 Query: 449 MSLMASLSNPYIVEYKDGWVDEGTSVCIVTSYCEGGDMAQRIKK 580 ++ +++P+IV+ + EG + ++ + GGD+ R+ K Sbjct: 119 RDILVEVNHPFIVKLHYAFQTEG-KLYLILDFLRGGDLFTRLSK 161
>KS6A3_HUMAN (P51812) Ribosomal protein S6 kinase alpha-3 (EC 2.7.11.1)| (S6K-alpha 3) (90 kDa ribosomal protein S6 kinase 3) (p90-RSK 3) (Ribosomal S6 kinase 2) (RSK-2) (pp90RSK2) (Insulin-stimulated protein kinase 1) (ISPK-1) (MAP kinase-activated protei Length = 740 Score = 43.9 bits (102), Expect = 3e-04 Identities = 29/91 (31%), Positives = 46/91 (50%), Gaps = 1/91 (1%) Frame = +2 Query: 305 YEVVEQIGRGAYGTAYLVHHKAERKRYVMKKIRLTKQNDKFQRTAYQEMSLMASL-SNPY 481 YEV E IG G+Y HKA + +K I DK +R +E+ ++ +P Sbjct: 422 YEVKEDIGVGSYSVCKRCIHKATNMEFAVKII------DKSKRDPTEEIEILLRYGQHPN 475 Query: 482 IVEYKDGWVDEGTSVCIVTSYCEGGDMAQRI 574 I+ KD + D+G V +VT +GG++ +I Sbjct: 476 IITLKDVY-DDGKYVYVVTELMKGGELLDKI 505 Score = 41.6 bits (96), Expect = 0.002 Identities = 23/104 (22%), Positives = 52/104 (50%), Gaps = 3/104 (2%) Frame = +2 Query: 278 GKARNPMEQYEVVEQIGRGAYGTAYLVHH---KAERKRYVMKKIRLTKQNDKFQRTAYQE 448 G + Q+E+++ +G+G++G +LV R+ Y MK ++ + + E Sbjct: 59 GHEKADPSQFELLKVLGQGSFGKVFLVKKISGSDARQLYAMKVLKKATLKVRDRVRTKME 118 Query: 449 MSLMASLSNPYIVEYKDGWVDEGTSVCIVTSYCEGGDMAQRIKK 580 ++ +++P+IV+ + EG + ++ + GGD+ R+ K Sbjct: 119 RDILVEVNHPFIVKLHYAFQTEG-KLYLILDFLRGGDLFTRLSK 161
>M4K3_MOUSE (Q99JP0) Mitogen-activated protein kinase kinase kinase kinase 3| (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 3) (MEK kinase kinase 3) (MEKKK 3) (Germinal center kinase-related protein kinase) (GLK) (Fragments) Length = 681 Score = 43.9 bits (102), Expect = 3e-04 Identities = 26/92 (28%), Positives = 43/92 (46%) Frame = +2 Query: 287 RNPMEQYEVVEQIGRGAYGTAYLVHHKAERKRYVMKKIRLTKQNDKFQRTAYQEMSLMAS 466 RNP E +E++++IG G YG Y + + +K I+L D QE+ +M Sbjct: 10 RNPQEDFELIQRIGSGTYGDVYKARNVNTGELAAIKVIKLEPGED--FAVVQQEIIMMKD 67 Query: 467 LSNPYIVEYKDGWVDEGTSVCIVTSYCEGGDM 562 +P IV Y ++ + I +C GG + Sbjct: 68 CKHPNIVAYFGSYL-RRDKLWICMEFCGGGSL 98
>SWE1_YEAST (P32944) Mitosis inhibitor protein kinase SWE1 (EC 2.7.11.1)| Length = 819 Score = 43.9 bits (102), Expect = 3e-04 Identities = 37/156 (23%), Positives = 67/156 (42%), Gaps = 16/156 (10%) Frame = +2 Query: 143 HHQRRALPVSSPEHHRIIYTRPAATASNSAPQDEHARARAKEQELGKAR---NP----ME 301 H + R L +SS I T + ++S + + +K + + + NP E Sbjct: 388 HRESRPLSLSSA-----IVTNTTSAETHSISSTDSSPLNSKRRLISSNKLSANPDSHLFE 442 Query: 302 QYEVVEQIGRGAYGTAYLVHHKAERKRYVMKKIRLTKQNDKFQRTAYQEMSLMASLSN-- 475 ++ V IG+G + T Y V K+Y +K I+ K N + E+ ++ ++N Sbjct: 443 KFTNVHSIGKGQFSTVYQVTFAQTNKKYAIKAIKPNKYNS--LKRILLEIKILNEVTNQI 500 Query: 476 -------PYIVEYKDGWVDEGTSVCIVTSYCEGGDM 562 YI++Y W + S I+T CE G++ Sbjct: 501 TMDQEGKEYIIDYISSWKFQ-NSYYIMTELCENGNL 535
>M4K3_HUMAN (Q8IVH8) Mitogen-activated protein kinase kinase kinase kinase 3| (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 3) (MEK kinase kinase 3) (MEKKK 3) (Germinal center kinase-related protein kinase) (GLK) Length = 894 Score = 43.9 bits (102), Expect = 3e-04 Identities = 26/92 (28%), Positives = 43/92 (46%) Frame = +2 Query: 287 RNPMEQYEVVEQIGRGAYGTAYLVHHKAERKRYVMKKIRLTKQNDKFQRTAYQEMSLMAS 466 RNP E +E++++IG G YG Y + + +K I+L D QE+ +M Sbjct: 10 RNPQEDFELIQRIGSGTYGDVYKARNVNTGELAAIKVIKLEPGED--FAVVQQEIIMMKD 67 Query: 467 LSNPYIVEYKDGWVDEGTSVCIVTSYCEGGDM 562 +P IV Y ++ + I +C GG + Sbjct: 68 CKHPNIVAYFGSYL-RRDKLWICMEFCGGGSL 98
>CC2H3_TRYBB (P54666) Cell division control protein 2 homolog 3 (EC 2.7.11.22)| Length = 311 Score = 43.9 bits (102), Expect = 3e-04 Identities = 19/71 (26%), Positives = 40/71 (56%) Frame = +2 Query: 287 RNPMEQYEVVEQIGRGAYGTAYLVHHKAERKRYVMKKIRLTKQNDKFQRTAYQEMSLMAS 466 ++ ++Y ++ +G G YG Y +A + +KK+RL + ++ +TA +E+S++ Sbjct: 17 KDQFDRYNRMDILGEGTYGVVYRAVDRATGQIVALKKVRLDRTDEGIPQTALREVSILQE 76 Query: 467 LSNPYIVEYKD 499 + +P IV D Sbjct: 77 IHHPNIVNLLD 87
>OBSCN_HUMAN (Q5VST9) Obscurin (Obscurin-myosin light chain kinase)| (Obscurin-MLCK) (Obscurin-RhoGEF) Length = 7968 Score = 43.5 bits (101), Expect = 4e-04 Identities = 26/90 (28%), Positives = 44/90 (48%) Frame = +2 Query: 305 YEVVEQIGRGAYGTAYLVHHKAERKRYVMKKIRLTKQNDKFQRTAYQEMSLMASLSNPYI 484 YEV E+IGRG +G V HK + K I L + + AY+E ++A+LS+P + Sbjct: 6468 YEVKEEIGRGVFGFVKRVQHKGNKILCAAKFIPL---RSRTRAQAYRERDILAALSHPLV 6524 Query: 485 VEYKDGWVDEGTSVCIVTSYCEGGDMAQRI 574 D + T + ++ C ++ R+ Sbjct: 6525 TGLLDQFETRKTLI-LILELCSSEELLDRL 6553
>RIM15_YEAST (P43565) Serine/threonine-protein kinase RIM15 (EC 2.7.11.1)| Length = 1770 Score = 43.5 bits (101), Expect = 4e-04 Identities = 37/153 (24%), Positives = 62/153 (40%), Gaps = 15/153 (9%) Frame = +2 Query: 164 PVSSPEHHRIIYTRPAATASNSAPQDEHARAR-------------AKEQELGKARNPMEQ 304 P+SSP + P SN A D A A Q + ++ Sbjct: 734 PISSPFTFSKDFLTPEQHPSNIARTDSINNAMLTSPNMPLSPLLLATNQTVKSPTPSIKD 793 Query: 305 YEVVEQIGRGAYGTAYLVHHKAERKRYVMKKIRLTKQNDKFQRT--AYQEMSLMASLSNP 478 Y++++ I +GAYG+ YL K + +K +R + K Q T + +M P Sbjct: 794 YDILKPISKGAYGSVYLARKKLTGDYFAIKVLRKSDMIAKNQVTNVKSERAIMMVQSDKP 853 Query: 479 YIVEYKDGWVDEGTSVCIVTSYCEGGDMAQRIK 577 Y+ + ++ ++ +V Y GGD+A IK Sbjct: 854 YVARLFASFQNK-DNLFLVMEYLPGGDLATLIK 885
>CD2L7_HUMAN (Q9NYV4) Cell division cycle 2-related protein kinase 7 (EC| 2.7.11.22) (CDC2-related protein kinase 7) (Cdc2-related kinase, arginine/serine-rich) (CrkRS) Length = 1490 Score = 43.5 bits (101), Expect = 4e-04 Identities = 22/85 (25%), Positives = 43/85 (50%) Frame = +2 Query: 245 HARARAKEQELGKARNPMEQYEVVEQIGRGAYGTAYLVHHKAERKRYVMKKIRLTKQNDK 424 + R E + GK +++++++ IG G YG Y K + +KK+RL + + Sbjct: 709 YGERRQTESDWGK--RCVDKFDIIGIIGEGTYGQVYKARDKDTGELVALKKVRLDNEKEG 766 Query: 425 FQRTAYQEMSLMASLSNPYIVEYKD 499 F TA +E+ ++ L + +V K+ Sbjct: 767 FPITAIREIKILRQLIHRSVVNMKE 791
>JAK_DROME (Q24592) Tyrosine-protein kinase hopscotch (EC 2.7.10.2)| Length = 1177 Score = 43.5 bits (101), Expect = 4e-04 Identities = 27/85 (31%), Positives = 45/85 (52%), Gaps = 1/85 (1%) Frame = +2 Query: 305 YEVVEQIGRGAYGTAYLVHHKAERKRYVMKKIRLTKQNDKFQRTAY-QEMSLMASLSNPY 481 Y + IGRG YGT Y H + K +++ + N T + +E+ +M +LS+P Sbjct: 892 YNMENMIGRGHYGTVYKGHLEFNDKDQPREQVAIKMLNTMQVSTDFHREIGIMRTLSHPN 951 Query: 482 IVEYKDGWVDEGTSVCIVTSYCEGG 556 IV++K W ++ S CI+ Y + G Sbjct: 952 IVKFK-YWAEK--SHCIIMEYLQSG 973
>TSSK4_MOUSE (Q9D411) Testis-specific serine/threonine-protein kinase 4 (EC| 2.7.11.1) (TSSK-4) (Testis-specific kinase 4) (TSK-4) Length = 328 Score = 43.1 bits (100), Expect = 6e-04 Identities = 27/101 (26%), Positives = 53/101 (52%), Gaps = 3/101 (2%) Frame = +2 Query: 287 RNPMEQY--EVVEQIGRGAYGTAYLVHHKAERKRYVMKKIRLTK-QNDKFQRTAYQEMSL 457 R+ ME+Y EV + IG G+YGT Y ++ ++ +K I K D + +E+ + Sbjct: 17 RSVMEEYGYEVGKIIGHGSYGTVYEAYYTKQKVMVAVKIISKKKASEDYLNKFLPREIQV 76 Query: 458 MASLSNPYIVEYKDGWVDEGTSVCIVTSYCEGGDMAQRIKK 580 M L + Y++ + ++ + V I+ +GGD+ + I++ Sbjct: 77 MKVLRHKYLINFYQA-IETTSRVYIILELAQGGDVLEWIQR 116
>E2AK3_HUMAN (Q9NZJ5) Eukaryotic translation initiation factor 2-alpha kinase 3| precursor (EC 2.7.11.1) (PRKR-like endoplasmic reticulum kinase) (Pancreatic eIF2-alpha kinase) (HsPEK) Length = 1115 Score = 43.1 bits (100), Expect = 6e-04 Identities = 19/72 (26%), Positives = 40/72 (55%) Frame = +2 Query: 296 MEQYEVVEQIGRGAYGTAYLVHHKAERKRYVMKKIRLTKQNDKFQRTAYQEMSLMASLSN 475 + +E ++ +GRG +G + +K + Y +K+IRL + + + +E+ +A L + Sbjct: 589 LTDFEPIQCLGRGGFGVVFEAKNKVDDCNYAIKRIRLPNR-ELAREKVMREVKALAKLEH 647 Query: 476 PYIVEYKDGWVD 511 P IV Y + W++ Sbjct: 648 PGIVRYFNAWLE 659
>KAPC_ASCSU (P49673) cAMP-dependent protein kinase catalytic subunit (EC| 2.7.11.11) (PKA C) Length = 337 Score = 43.1 bits (100), Expect = 6e-04 Identities = 24/91 (26%), Positives = 51/91 (56%), Gaps = 2/91 (2%) Frame = +2 Query: 296 MEQYEVVEQIGRGAYGTAYLVHHKAERKRYVMKKIRLTKQNDKFQ-RTAYQEMSLMASLS 472 ++ ++ + IG G++G YLV H+A + + +KK+ + + Q + E L++ LS Sbjct: 26 VDDFDRICTIGTGSFGRVYLVQHRASEQYFALKKMAIREVVSMRQTEHVHSEKRLLSRLS 85 Query: 473 NPYIVE-YKDGWVDEGTSVCIVTSYCEGGDM 562 +P+IV+ Y W + ++ ++ Y GG++ Sbjct: 86 HPFIVKMYCASW--DKYNLYMLFEYLAGGEL 114
>STE20_CANAL (Q92212) Serine/threonine-protein kinase STE20 homolog (EC 2.7.11.1)| Length = 1230 Score = 43.1 bits (100), Expect = 6e-04 Identities = 34/127 (26%), Positives = 61/127 (48%), Gaps = 7/127 (5%) Frame = +2 Query: 203 RPAATASNSAPQDEHARARAKEQELGKAR------NPMEQYEVVEQIGRGAYGTAYLVHH 364 R A A+ A + + R Q + K + +P E Y + +IG+GA G +L H Sbjct: 913 RDAKQAALIAQKKREEKKRKNLQIIAKLKTICNPGDPNELYVDLVKIGQGASGGVFLAHD 972 Query: 365 KAERKRYV-MKKIRLTKQNDKFQRTAYQEMSLMASLSNPYIVEYKDGWVDEGTSVCIVTS 541 ++ V +K++ L +Q K E+ +M S+P IV + D ++ +G + ++ Sbjct: 973 VRDKSNIVAIKQMNLEQQPKK--ELIINEILVMKGSSHPNIVNFIDSYLLKG-DLWVIME 1029 Query: 542 YCEGGDM 562 Y EGG + Sbjct: 1030 YMEGGSL 1036
>CDC2D_ANTMA (Q38775) Cell division control protein 2 homolog D (EC 2.7.11.22)| (EC 2.7.11.23) Length = 312 Score = 43.1 bits (100), Expect = 6e-04 Identities = 26/81 (32%), Positives = 43/81 (53%), Gaps = 4/81 (4%) Frame = +2 Query: 296 MEQYEVVEQIGRGAYGTAYLVHHKAERKRYVMKKIRLTKQNDKFQRTAYQEMSLMASLS- 472 M+ + +E++G G YG Y K+ K +KK RL + + T +E+SL+ LS Sbjct: 11 MDAFVKLEKVGEGTYGKVYRAMEKSTGKIVALKKTRLHEDEEGVPPTTLREVSLLRMLSR 70 Query: 473 NPYIV---EYKDGWVDEGTSV 526 +P++V + K G EG +V Sbjct: 71 DPHVVRLLDVKQGQNKEGKTV 91
>KS6A1_MOUSE (P18653) Ribosomal protein S6 kinase alpha-1 (EC 2.7.11.1)| (S6K-alpha 1) (90 kDa ribosomal protein S6 kinase 1) (p90-RSK 1) (Ribosomal S6 kinase 1) (RSK-1) (pp90RSK1) (MAP kinase-activated protein kinase 1a) (MAPKAPK1A) Length = 724 Score = 43.1 bits (100), Expect = 6e-04 Identities = 35/116 (30%), Positives = 54/116 (46%), Gaps = 2/116 (1%) Frame = +2 Query: 233 PQDEHARARAKEQEL-GKARNPMEQYEVVEQIGRGAYGTAYLVHHKAERKRYVMKKIRLT 409 P+ A + Q+L GK + Y V E IG G+Y HKA Y +K I Sbjct: 382 PRTTQAPLHSVVQQLHGKNLVFSDGYVVKETIGVGSYSVCKRCVHKATNMEYAVKVI--- 438 Query: 410 KQNDKFQRTAYQEMSLMASL-SNPYIVEYKDGWVDEGTSVCIVTSYCEGGDMAQRI 574 DK +R +E+ ++ +P I+ KD + D+G V +VT GG++ +I Sbjct: 439 ---DKSKRDPSEEIEILLRYGQHPNIITLKDVY-DDGKHVYLVTELMRGGELLDKI 490 Score = 40.8 bits (94), Expect = 0.003 Identities = 24/105 (22%), Positives = 53/105 (50%), Gaps = 4/105 (3%) Frame = +2 Query: 278 GKARNPMEQYEVVEQIGRGAYGTAYLVHHKAER----KRYVMKKIRLTKQNDKFQRTAYQ 445 G + Q+E+++ +G+G++G +LV K R Y MK ++ + + Sbjct: 53 GSEKADPSQFELLKVLGQGSFGKVFLV-RKVTRPDSGHLYAMKVLKKATLKVRDRVRTKM 111 Query: 446 EMSLMASLSNPYIVEYKDGWVDEGTSVCIVTSYCEGGDMAQRIKK 580 E ++A +++P++V+ + EG + ++ + GGD+ R+ K Sbjct: 112 ERDILADVNHPFVVKLHYAFQTEG-KLYLILDFLRGGDLFTRLSK 155
>CDC2H_PLAYO (Q7RM49) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) Length = 289 Score = 42.7 bits (99), Expect = 7e-04 Identities = 23/69 (33%), Positives = 42/69 (60%), Gaps = 1/69 (1%) Frame = +2 Query: 296 MEQYEVVEQIGRGAYGTAYLVHHKAERKRYVMKKIRLTKQNDKFQRT-AYQEMSLMASLS 472 ME+Y +E+IG G YG Y + ++ + + +KKIRL K+++ T + +E+S++ L Sbjct: 1 MEKYHGLEKIGEGTYGVVYKAQN-SDGESFALKKIRLEKEDEGIPSTVSIREISILKELR 59 Query: 473 NPYIVEYKD 499 + IV+ D Sbjct: 60 HSNIVKLYD 68
>E2AK3_RAT (Q9Z1Z1) Eukaryotic translation initiation factor 2-alpha kinase 3| precursor (EC 2.7.11.1) (PRKR-like endoplasmic reticulum kinase) (Pancreatic eIF2-alpha kinase) Length = 1108 Score = 42.7 bits (99), Expect = 7e-04 Identities = 19/72 (26%), Positives = 40/72 (55%) Frame = +2 Query: 296 MEQYEVVEQIGRGAYGTAYLVHHKAERKRYVMKKIRLTKQNDKFQRTAYQEMSLMASLSN 475 + +E ++ +GRG +G + +K + Y +K+IRL + + + +E+ +A L + Sbjct: 582 LTDFEPIQCMGRGGFGVVFEAKNKVDDCNYAIKRIRLPNR-ELAREKVMREVKALAKLEH 640 Query: 476 PYIVEYKDGWVD 511 P IV Y + W++ Sbjct: 641 PGIVRYFNAWLE 652
>BUR1_ASHGO (Q75D46) Serine/threonine-protein kinase BUR1 (EC 2.7.11.22) (EC| 2.7.11.23) Length = 753 Score = 42.7 bits (99), Expect = 7e-04 Identities = 19/62 (30%), Positives = 39/62 (62%) Frame = +2 Query: 305 YEVVEQIGRGAYGTAYLVHHKAERKRYVMKKIRLTKQNDKFQRTAYQEMSLMASLSNPYI 484 Y+ +++G+G +G Y H A +++ MKKI + +ND F TA +E++++ L++ + Sbjct: 56 YKEEKKLGQGTFGEVYRGVHLATQRQVAMKKILVKTENDLFPITAQREITILKRLNHRNV 115 Query: 485 VE 490 V+ Sbjct: 116 VQ 117
>KS6A6_HUMAN (Q9UK32) Ribosomal protein S6 kinase alpha-6 (EC 2.7.11.1)| (S6K-alpha 6) (90 kDa ribosomal protein S6 kinase 6) (p90-RSK 6) (Ribosomal S6 kinase 4) (RSK-4) (pp90RSK4) Length = 745 Score = 42.7 bits (99), Expect = 7e-04 Identities = 33/102 (32%), Positives = 48/102 (47%), Gaps = 1/102 (0%) Frame = +2 Query: 278 GKARNPMEQYEVVEQIGRGAYGTAYLVHHKAERKRYVMKKIRLTKQNDKFQRTAYQEMS- 454 G A E YE+ E IG G+Y H + +K I DK +R +E+ Sbjct: 417 GNAAQFGEVYELKEDIGVGSYSVCKRCIHATTNMEFAVKII------DKSKRDPSEEIEI 470 Query: 455 LMASLSNPYIVEYKDGWVDEGTSVCIVTSYCEGGDMAQRIKK 580 LM +P I+ KD + D+G V +VT +GG++ RI K Sbjct: 471 LMRYGQHPNIITLKDVF-DDGRYVYLVTDLMKGGELLDRILK 511 Score = 41.6 bits (96), Expect = 0.002 Identities = 22/96 (22%), Positives = 50/96 (52%), Gaps = 3/96 (3%) Frame = +2 Query: 302 QYEVVEQIGRGAYGTAYLVHHKA---ERKRYVMKKIRLTKQNDKFQRTAYQEMSLMASLS 472 Q+E+++ +G+G++G +LV K + Y MK ++ + + E ++ ++ Sbjct: 72 QFELLKVLGQGSFGKVFLVRKKTGPDAGQLYAMKVLKKASLKVRDRVRTKMERDILVEVN 131 Query: 473 NPYIVEYKDGWVDEGTSVCIVTSYCEGGDMAQRIKK 580 +P+IV+ + EG + ++ + GGD+ R+ K Sbjct: 132 HPFIVKLHYAFQTEG-KLYLILDFLRGGDVFTRLSK 166
>TLK1_MOUSE (Q8C0V0) Serine/threonine-protein kinase tousled-like 1 (EC| 2.7.11.1) (Tousled-like kinase 1) Length = 766 Score = 42.7 bits (99), Expect = 7e-04 Identities = 25/99 (25%), Positives = 48/99 (48%), Gaps = 5/99 (5%) Frame = +2 Query: 299 EQYEVVEQIGRGAYGTAYLVHHKAERKRYVMKKIRLTK-----QNDKFQRTAYQEMSLMA 463 E+Y ++ +GRG + Y E++ +K +L K + + + + A +E + Sbjct: 454 ERYLLLHLLGRGGFSEVYKAFDLYEQRYAAVKIHQLNKSWRDEKKENYHKHACREYRIHK 513 Query: 464 SLSNPYIVEYKDGWVDEGTSVCIVTSYCEGGDMAQRIKK 580 L +P IV+ D + + + C V YCEG D+ +K+ Sbjct: 514 ELDHPRIVKLYDYFSLDTDTFCTVLEYCEGNDLDFYLKQ 552
>TLK1_HUMAN (Q9UKI8) Serine/threonine-protein kinase tousled-like 1 (EC| 2.7.11.1) (Tousled-like kinase 1) (PKU-beta) Length = 766 Score = 42.7 bits (99), Expect = 7e-04 Identities = 25/99 (25%), Positives = 48/99 (48%), Gaps = 5/99 (5%) Frame = +2 Query: 299 EQYEVVEQIGRGAYGTAYLVHHKAERKRYVMKKIRLTK-----QNDKFQRTAYQEMSLMA 463 E+Y ++ +GRG + Y E++ +K +L K + + + + A +E + Sbjct: 454 ERYLLLHLLGRGGFSEVYKAFDLYEQRYAAVKIHQLNKSWRDEKKENYHKHACREYRIHK 513 Query: 464 SLSNPYIVEYKDGWVDEGTSVCIVTSYCEGGDMAQRIKK 580 L +P IV+ D + + + C V YCEG D+ +K+ Sbjct: 514 ELDHPRIVKLYDYFSLDTDTFCTVLEYCEGNDLDFYLKQ 552
>STK38_MOUSE (Q91VJ4) Serine/threonine-protein kinase 38 (EC 2.7.11.1) (NDR1| protein kinase) (Nuclear Dbf2-related kinase 1) Length = 465 Score = 42.7 bits (99), Expect = 7e-04 Identities = 30/113 (26%), Positives = 54/113 (47%), Gaps = 1/113 (0%) Frame = +2 Query: 245 HARARAKEQELGKARNPMEQYEVVEQIGRGAYGTAYLVHHKAERKRYVMKKIRLTKQNDK 424 HAR + L + R +E +E ++ IGRGA+G LV K Y MK +R +K Sbjct: 69 HARKETEFLRLKRTRLGLEDFESLKVIGRGAFGEVRLVQKKDTGHVYAMKILRKADMLEK 128 Query: 425 FQRTAYQ-EMSLMASLSNPYIVEYKDGWVDEGTSVCIVTSYCEGGDMAQRIKK 580 Q + E ++ + ++V+ + D+ ++ ++ + GGDM + K Sbjct: 129 EQVGHIRAERDILVEADSLWVVKMFYSFQDK-LNLYLIMEFLPGGDMMTLLMK 180
>STK38_HUMAN (Q15208) Serine/threonine-protein kinase 38 (EC 2.7.11.1) (NDR1| protein kinase) (Nuclear Dbf2-related kinase 1) Length = 465 Score = 42.7 bits (99), Expect = 7e-04 Identities = 30/113 (26%), Positives = 54/113 (47%), Gaps = 1/113 (0%) Frame = +2 Query: 245 HARARAKEQELGKARNPMEQYEVVEQIGRGAYGTAYLVHHKAERKRYVMKKIRLTKQNDK 424 HAR + L + R +E +E ++ IGRGA+G LV K Y MK +R +K Sbjct: 69 HARKETEFLRLKRTRLGLEDFESLKVIGRGAFGEVRLVQKKDTGHVYAMKILRKADMLEK 128 Query: 425 FQRTAYQ-EMSLMASLSNPYIVEYKDGWVDEGTSVCIVTSYCEGGDMAQRIKK 580 Q + E ++ + ++V+ + D+ ++ ++ + GGDM + K Sbjct: 129 EQVGHIRAERDILVEADSLWVVKMFYSFQDK-LNLYLIMEFLPGGDMMTLLMK 180
>PCTK2_HUMAN (Q00537) Serine/threonine-protein kinase PCTAIRE-2 (EC 2.7.11.22)| (PCTAIRE-motif protein kinase 2) Length = 523 Score = 42.7 bits (99), Expect = 7e-04 Identities = 33/110 (30%), Positives = 51/110 (46%), Gaps = 1/110 (0%) Frame = +2 Query: 224 NSAPQDEHARARAKEQELGKAR-NPMEQYEVVEQIGRGAYGTAYLVHHKAERKRYVMKKI 400 NS P D+ R++ L + ME Y +E++G G Y T Y K +K+I Sbjct: 164 NSPPFDQPMSRRSRRASLSEIGFGKMETYIKLEKLGEGTYATVYKGRSKLTENLVALKEI 223 Query: 401 RLTKQNDKFQRTAYQEMSLMASLSNPYIVEYKDGWVDEGTSVCIVTSYCE 550 RL + + TA +E+SL+ L + IV D V S+ +V Y + Sbjct: 224 RL-EHEEGAPCTAIREVSLLKDLKHANIVTLHD-IVHTDKSLTLVFEYLD 271
>BUR1_ASPFU (Q4WTN5) Serine/threonine-protein kinase bur1 (EC 2.7.11.22) (EC| 2.7.11.23) Length = 580 Score = 42.7 bits (99), Expect = 7e-04 Identities = 29/115 (25%), Positives = 52/115 (45%), Gaps = 7/115 (6%) Frame = +2 Query: 227 SAPQDEHARARAKEQELGKARNPMEQYEVVEQIGRGAYGTAYLVHHKAERKRYVMKKIRL 406 S +D+H R + + +E + ++G G +G Y K + +KKI + Sbjct: 5 SLERDDHGNPRFR------GCTSIRDFEFLGKLGEGTFGEVYKARSKKDGSIVALKKILM 58 Query: 407 TKQNDKFQRTAYQEMSLMASLSNPYIVEYKDGWVDEG-------TSVCIVTSYCE 550 + D F TA +E+ L+ LS+ I++ K+ V+ S+ +VT Y E Sbjct: 59 HNEKDGFPITALREIKLLKMLSHRNILQLKEMAVERSKGDGRKKPSMYMVTPYME 113
>E2AK3_MOUSE (Q9Z2B5) Eukaryotic translation initiation factor 2-alpha kinase 3| precursor (EC 2.7.11.1) (PRKR-like endoplasmic reticulum kinase) (Pancreatic eIF2-alpha kinase) Length = 1114 Score = 42.7 bits (99), Expect = 7e-04 Identities = 19/72 (26%), Positives = 40/72 (55%) Frame = +2 Query: 296 MEQYEVVEQIGRGAYGTAYLVHHKAERKRYVMKKIRLTKQNDKFQRTAYQEMSLMASLSN 475 + +E ++ +GRG +G + +K + Y +K+IRL + + + +E+ +A L + Sbjct: 586 LTDFEPIQCMGRGGFGVVFEAKNKVDDCNYAIKRIRLPNR-ELAREKVMREVKALAKLEH 644 Query: 476 PYIVEYKDGWVD 511 P IV Y + W++ Sbjct: 645 PGIVRYFNAWLE 656
>SCH9_YEAST (P11792) Serine/threonine-protein kinase SCH9 (EC 2.7.11.1)| Length = 823 Score = 42.4 bits (98), Expect = 0.001 Identities = 28/98 (28%), Positives = 51/98 (52%), Gaps = 4/98 (4%) Frame = +2 Query: 299 EQYEVVEQIGRGAYGTAYLVHHKAERKRYVMK---KIRLTKQNDKFQRTAYQEMSL-MAS 466 + +EV+ +G+G +G Y V K ++ Y MK K + K+N+ + + + AS Sbjct: 409 QDFEVLRLLGKGTFGQVYQVKKKDTQRIYAMKVLSKKVIVKKNEIAHTIGERNILVTTAS 468 Query: 467 LSNPYIVEYKDGWVDEGTSVCIVTSYCEGGDMAQRIKK 580 S+P+IV K + T + +VT Y GG++ ++K Sbjct: 469 KSSPFIVGLKFSF-QTPTDLYLVTDYMSGGELFWHLQK 505
>KS6A1_HUMAN (Q15418) Ribosomal protein S6 kinase alpha-1 (EC 2.7.11.1)| (S6K-alpha 1) (90 kDa ribosomal protein S6 kinase 1) (p90-RSK 1) (Ribosomal S6 kinase 1) (RSK-1) (pp90RSK1) (MAP kinase-activated protein kinase 1a) (MAPKAPK1A) Length = 735 Score = 42.4 bits (98), Expect = 0.001 Identities = 35/116 (30%), Positives = 54/116 (46%), Gaps = 2/116 (1%) Frame = +2 Query: 233 PQDEHARARAKEQEL-GKARNPMEQYEVVEQIGRGAYGTAYLVHHKAERKRYVMKKIRLT 409 P+ A + Q+L GK + Y V E IG G+Y HKA Y +K I Sbjct: 393 PRAPQAPLHSVVQQLHGKNLVFSDGYVVKETIGVGSYSECKRCVHKATNMEYAVKVI--- 449 Query: 410 KQNDKFQRTAYQEMSLMASL-SNPYIVEYKDGWVDEGTSVCIVTSYCEGGDMAQRI 574 DK +R +E+ ++ +P I+ KD + D+G V +VT GG++ +I Sbjct: 450 ---DKSKRDPSEEIEILLRYGQHPNIITLKDVY-DDGKHVYLVTELMRGGELLDKI 501 Score = 38.9 bits (89), Expect = 0.011 Identities = 21/104 (20%), Positives = 50/104 (48%), Gaps = 3/104 (2%) Frame = +2 Query: 278 GKARNPMEQYEVVEQIGRGAYGTAYLVHHKAERKR---YVMKKIRLTKQNDKFQRTAYQE 448 G + +E+++ +G+G++G +LV Y MK ++ + + E Sbjct: 53 GSEKADPSHFELLKVLGQGSFGKVFLVRKVTRPDSGHLYAMKVLKKATLKVRDRVRTKME 112 Query: 449 MSLMASLSNPYIVEYKDGWVDEGTSVCIVTSYCEGGDMAQRIKK 580 ++A +++P++V+ + EG + ++ + GGD+ R+ K Sbjct: 113 RDILADVNHPFVVKLHYAFQTEG-KLYLILDFLRGGDLFTRLSK 155
>KCC4_HUMAN (Q16566) Calcium/calmodulin-dependent protein kinase type IV (EC| 2.7.11.17) (CAM kinase-GR) (CaMK IV) Length = 473 Score = 42.4 bits (98), Expect = 0.001 Identities = 27/90 (30%), Positives = 48/90 (53%) Frame = +2 Query: 305 YEVVEQIGRGAYGTAYLVHHKAERKRYVMKKIRLTKQNDKFQRTAYQEMSLMASLSNPYI 484 +EV ++GRGA Y K +K Y +K ++ T + K RT E+ ++ LS+P I Sbjct: 46 FEVESELGRGATSIVYRCKQKGTQKPYALKVLKKT-VDKKIVRT---EIGVLLRLSHPNI 101 Query: 485 VEYKDGWVDEGTSVCIVTSYCEGGDMAQRI 574 ++ K+ + + T + +V GG++ RI Sbjct: 102 IKLKEIF-ETPTEISLVLELVTGGELFDRI 130
>E2AK2_MOUSE (Q03963) Interferon-induced, double-stranded RNA-activated protein| kinase (EC 2.7.11.1) (Interferon-inducible RNA-dependent protein kinase) (Protein kinase RNA-activated) (PKR) (p68 kinase) (P1/eIF-2A protein kinase) (Serine/threonine-protein Length = 515 Score = 42.4 bits (98), Expect = 0.001 Identities = 19/67 (28%), Positives = 36/67 (53%) Frame = +2 Query: 305 YEVVEQIGRGAYGTAYLVHHKAERKRYVMKKIRLTKQNDKFQRTAYQEMSLMASLSNPYI 484 +E +E+IG G +G + H+ + KRY +K+++ + A E+ +A L++ I Sbjct: 242 FEDIEEIGLGGFGQVFKAKHRIDGKRYAIKRVKYNTEK------AEHEVQALAELNHVNI 295 Query: 485 VEYKDGW 505 V+Y W Sbjct: 296 VQYHSCW 302
>ATG1_SCHPO (Q9Y7T4) Serine/threonine-protein kinase atg1 (EC 2.7.11.1)| (Autophagy-related protein 1) Length = 830 Score = 42.4 bits (98), Expect = 0.001 Identities = 23/92 (25%), Positives = 43/92 (46%) Frame = +2 Query: 305 YEVVEQIGRGAYGTAYLVHHKAERKRYVMKKIRLTKQNDKFQRTAYQEMSLMASLSNPYI 484 Y + +IGRG++ Y H + +K + K K E+S++ + + ++ Sbjct: 14 YVIRSEIGRGSFAIVYKGKHTETNRVISIKSVLTKKLTKKLLENLESEISILKEIRHVHV 73 Query: 485 VEYKDGWVDEGTSVCIVTSYCEGGDMAQRIKK 580 VE D + G + +V YC GD++ I+K Sbjct: 74 VELID-CIKAGRFIHLVMEYCSLGDLSYFIRK 104
>BUR1_CANGA (Q6FQ83) Serine/threonine-protein kinase BUR1 (EC 2.7.11.22) (EC| 2.7.11.23) Length = 667 Score = 42.4 bits (98), Expect = 0.001 Identities = 18/62 (29%), Positives = 39/62 (62%) Frame = +2 Query: 305 YEVVEQIGRGAYGTAYLVHHKAERKRYVMKKIRLTKQNDKFQRTAYQEMSLMASLSNPYI 484 Y+ E++G+G +G Y H +++ MK+I + ++ND F TA +E++++ L++ I Sbjct: 60 YKEEEKLGQGTFGEVYKGLHLQTQRKVAMKRIIVNQENDLFPITAQREITILKRLNHKNI 119 Query: 485 VE 490 ++ Sbjct: 120 IK 121
>STK10_HUMAN (O94804) Serine/threonine-protein kinase 10 (EC 2.7.11.1)| (Lymphocyte-oriented kinase) Length = 968 Score = 42.4 bits (98), Expect = 0.001 Identities = 25/89 (28%), Positives = 47/89 (52%) Frame = +2 Query: 290 NPMEQYEVVEQIGRGAYGTAYLVHHKAERKRYVMKKIRLTKQNDKFQRTAYQEMSLMASL 469 +P E +E+V ++G GA+G Y +K E K+ TK ++ + E+ ++A+ Sbjct: 31 DPNEVWEIVGELGDGAFGKVYKAKNK-ETGALAAAKVIETKSEEELE-DYIVEIEILATC 88 Query: 470 SNPYIVEYKDGWVDEGTSVCIVTSYCEGG 556 +PYIV+ + +G + I+ +C GG Sbjct: 89 DHPYIVKLLGAYYHDG-KLWIMIEFCPGG 116
>KS6A2_MOUSE (Q9WUT3) Ribosomal protein S6 kinase alpha-2 (EC 2.7.11.1)| (S6K-alpha 2) (90 kDa ribosomal protein S6 kinase 2) (p90-RSK 2) (Ribosomal S6 kinase 3) (RSK-3) (pp90RSK3) (Protein-tyrosine kinase Mpk-9) (MAP kinase-activated protein kinase 1c) (M Length = 733 Score = 42.4 bits (98), Expect = 0.001 Identities = 29/91 (31%), Positives = 44/91 (48%), Gaps = 1/91 (1%) Frame = +2 Query: 305 YEVVEQIGRGAYGTAYLVHHKAERKRYVMKKIRLTKQNDKFQRTAYQEMSLMASL-SNPY 481 YE+ E IG G+Y HKA Y +K I DK +R +E+ ++ +P Sbjct: 415 YEIKEDIGVGSYSVCKRCVHKATDAEYAVKII------DKSKRDPSEEIEILLRYGQHPN 468 Query: 482 IVEYKDGWVDEGTSVCIVTSYCEGGDMAQRI 574 I+ KD + D+G V +V GG++ RI Sbjct: 469 IITLKDVY-DDGKYVYLVMELMRGGELLDRI 498 Score = 42.4 bits (98), Expect = 0.001 Identities = 23/96 (23%), Positives = 51/96 (53%), Gaps = 3/96 (3%) Frame = +2 Query: 302 QYEVVEQIGRGAYGTAYLVHH---KAERKRYVMKKIRLTKQNDKFQRTAYQEMSLMASLS 472 Q+E+++ +G+G+YG +LV + Y MK ++ + + + E ++A ++ Sbjct: 58 QFELLKVLGQGSYGKVFLVRKVTGSDAGQLYAMKVLKKATLKVRDRVRSKMERDILAEVN 117 Query: 473 NPYIVEYKDGWVDEGTSVCIVTSYCEGGDMAQRIKK 580 +P+IV+ + EG + ++ + GGD+ R+ K Sbjct: 118 HPFIVKLHYAFQTEG-KLYLILDFLRGGDLFTRLSK 152
>KS6A2_HUMAN (Q15349) Ribosomal protein S6 kinase alpha-2 (EC 2.7.11.1)| (S6K-alpha 2) (90 kDa ribosomal protein S6 kinase 2) (p90-RSK 2) (Ribosomal S6 kinase 3) (RSK-3) (pp90RSK3) (MAP kinase-activated protein kinase 1c) (MAPKAPK1C) Length = 733 Score = 42.4 bits (98), Expect = 0.001 Identities = 29/91 (31%), Positives = 44/91 (48%), Gaps = 1/91 (1%) Frame = +2 Query: 305 YEVVEQIGRGAYGTAYLVHHKAERKRYVMKKIRLTKQNDKFQRTAYQEMSLMASL-SNPY 481 YE+ E IG G+Y HKA Y +K I DK +R +E+ ++ +P Sbjct: 415 YEIKEDIGVGSYSVCKRCVHKATDTEYAVKII------DKSKRDPSEEIEILLRYGQHPN 468 Query: 482 IVEYKDGWVDEGTSVCIVTSYCEGGDMAQRI 574 I+ KD + D+G V +V GG++ RI Sbjct: 469 IITLKDVY-DDGKFVYLVMELMRGGELLDRI 498 Score = 42.4 bits (98), Expect = 0.001 Identities = 23/96 (23%), Positives = 51/96 (53%), Gaps = 3/96 (3%) Frame = +2 Query: 302 QYEVVEQIGRGAYGTAYLVHH---KAERKRYVMKKIRLTKQNDKFQRTAYQEMSLMASLS 472 Q+E+++ +G+G+YG +LV + Y MK ++ + + + E ++A ++ Sbjct: 58 QFELLKVLGQGSYGKVFLVRKVKGSDAGQLYAMKVLKKATLKVRDRVRSKMERDILAEVN 117 Query: 473 NPYIVEYKDGWVDEGTSVCIVTSYCEGGDMAQRIKK 580 +P+IV+ + EG + ++ + GGD+ R+ K Sbjct: 118 HPFIVKLHYAFQTEG-KLYLILDFLRGGDLFTRLSK 152
>CRK1_LEIME (Q06309) Cell division protein kinase 2 homolog CRK1 (EC 2.7.11.23)| Length = 301 Score = 42.0 bits (97), Expect = 0.001 Identities = 22/66 (33%), Positives = 34/66 (51%) Frame = +2 Query: 302 QYEVVEQIGRGAYGTAYLVHHKAERKRYVMKKIRLTKQNDKFQRTAYQEMSLMASLSNPY 481 +YE E+IG G YG Y + +K+IRL + + TA +E+SL+ L + Sbjct: 4 RYERQEKIGEGTYGVVYKARDTSTAATVALKRIRLDSEEEGVPCTAIREISLLKELRHEN 63 Query: 482 IVEYKD 499 IV+ D Sbjct: 64 IVKLLD 69
>E2AK3_DROME (Q9NIV1) Eukaryotic translation initiation factor 2-alpha kinase| precursor (EC 2.7.11.1) (PRKR-like endoplasmic reticulum kinase) (PERK) (PEK) (DmPEK) Length = 1162 Score = 42.0 bits (97), Expect = 0.001 Identities = 20/69 (28%), Positives = 36/69 (52%) Frame = +2 Query: 305 YEVVEQIGRGAYGTAYLVHHKAERKRYVMKKIRLTKQNDKFQRTAYQEMSLMASLSNPYI 484 +E+++ +GRG +G + +K + RY +K+I L + QR +E +AS + I Sbjct: 642 FELMQCLGRGGFGVVFEAKNKLDENRYAIKRITLPNKESSRQR-VLREARTLASCEHHNI 700 Query: 485 VEYKDGWVD 511 V Y W + Sbjct: 701 VRYFHSWTE 709
>NUAK1_MOUSE (Q641K5) NUAK family, SNF1-like kinase 1 (EC 2.7.11.1)| Length = 658 Score = 41.6 bits (96), Expect = 0.002 Identities = 29/124 (23%), Positives = 56/124 (45%), Gaps = 1/124 (0%) Frame = +2 Query: 212 ATASNSAPQDEHARARAKEQELGKARNPMEQYEVVEQIGRGAYGTAYLVHHKAERKRYVM 391 ATA+ P+ H R + N +YE+ E +G+G YG + + + Sbjct: 30 ATAAPVEPRKPHGVKRHHHKH-----NLKHRYELQETLGKGTYGKVKRATERFSGRVVAI 84 Query: 392 KKIRLTKQNDKFQRT-AYQEMSLMASLSNPYIVEYKDGWVDEGTSVCIVTSYCEGGDMAQ 568 K IR K D+ +E+ +M+SL++P+I+ + + + + I+ Y G++ Sbjct: 85 KSIRKDKIKDELDMVHIRREIEIMSSLNHPHIISIYEVF-ENKDKIVIIMEYASKGELYD 143 Query: 569 RIKK 580 I + Sbjct: 144 YISE 147
>KS6A1_RAT (Q63531) Ribosomal protein S6 kinase alpha-1 (EC 2.7.11.1)| (S6K-alpha 1) (90 kDa ribosomal protein S6 kinase 1) (p90-RSK 1) (Ribosomal S6 kinase 1) (RSK-1) (pp90RSK1) (MAP kinase-activated protein kinase 1a) (MAPKAPK1A) Length = 735 Score = 41.6 bits (96), Expect = 0.002 Identities = 35/119 (29%), Positives = 55/119 (46%), Gaps = 2/119 (1%) Frame = +2 Query: 224 NSAPQDEHARARAKEQEL-GKARNPMEQYEVVEQIGRGAYGTAYLVHHKAERKRYVMKKI 400 +S P+ A + Q+L GK + Y V E IG G+Y HKA Y +K I Sbjct: 390 DSKPRATQAPLHSVVQQLHGKNLVFSDGYIVKETIGVGSYSVCKRCVHKATNMEYAVKVI 449 Query: 401 RLTKQNDKFQRTAYQEMSLMASL-SNPYIVEYKDGWVDEGTSVCIVTSYCEGGDMAQRI 574 DK +R +E+ ++ +P I+ KD + D+ V +VT GG++ +I Sbjct: 450 ------DKSKRDPSEEIEILLRYGQHPNIITLKDVY-DDSKHVYLVTELMRGGELLDKI 501 Score = 39.3 bits (90), Expect = 0.008 Identities = 21/104 (20%), Positives = 50/104 (48%), Gaps = 3/104 (2%) Frame = +2 Query: 278 GKARNPMEQYEVVEQIGRGAYGTAYLVHHKAERKR---YVMKKIRLTKQNDKFQRTAYQE 448 G + +E+++ +G+G++G +LV Y MK ++ + + E Sbjct: 53 GSEKADPSHFELLKVLGQGSFGKVFLVRKVTRPDNGHLYAMKVLKKATLKVRDRVRTKME 112 Query: 449 MSLMASLSNPYIVEYKDGWVDEGTSVCIVTSYCEGGDMAQRIKK 580 ++A +++P++V+ + EG + ++ + GGD+ R+ K Sbjct: 113 RDILADVNHPFVVKLHYAFQTEG-KLYLILDFLRGGDLFTRLSK 155
>CDK2_ENTHI (Q04770) Cell division protein kinase 2 homolog (EC 2.7.11.22)| Length = 291 Score = 41.6 bits (96), Expect = 0.002 Identities = 21/85 (24%), Positives = 45/85 (52%) Frame = +2 Query: 296 MEQYEVVEQIGRGAYGTAYLVHHKAERKRYVMKKIRLTKQNDKFQRTAYQEMSLMASLSN 475 M +YE +Q+G G YG + +KKI+ +++D T+ +E++++ L + Sbjct: 1 MTRYEKKQQLGEGTYGVVCKAWDTVCNRYVALKKIKQEREDDGIPVTSVREIAVLLELKH 60 Query: 476 PYIVEYKDGWVDEGTSVCIVTSYCE 550 P +V+ D ++ E + +V +C+ Sbjct: 61 PNVVDLYDIYL-EDKFLYLVFEFCD 84
>ST38L_MOUSE (Q7TSE6) Serine/threonine-protein kinase 38-like (EC 2.7.11.1)| (NDR2 protein kinase) (Nuclear Dbf2-related kinase 2) Length = 464 Score = 41.6 bits (96), Expect = 0.002 Identities = 28/116 (24%), Positives = 54/116 (46%), Gaps = 1/116 (0%) Frame = +2 Query: 236 QDEHARARAKEQELGKARNPMEQYEVVEQIGRGAYGTAYLVHHKAERKRYVMKKIRLTKQ 415 + +HAR + L + R ++ +E ++ I RGA+G LV K Y MK +R Sbjct: 67 RSQHARKETEFLRLKRTRLGLDDFESLKVIARGAFGEVRLVQKKDTGHIYAMKILRKADM 126 Query: 416 NDKFQRTAYQ-EMSLMASLSNPYIVEYKDGWVDEGTSVCIVTSYCEGGDMAQRIKK 580 +K Q + E ++ ++V+ + D+ ++ ++ + GGDM + K Sbjct: 127 LEKEQVAHIRAERDILVEADGAWVVKMFYSFQDK-RNLYLIMEFLPGGDMMTLLMK 181
>NRC2_NEUCR (O42626) Serine/threonine-protein kinase nrc-2 (EC 2.7.11.1)| (Nonrepressible conidiation protein 2) Length = 623 Score = 41.6 bits (96), Expect = 0.002 Identities = 27/96 (28%), Positives = 50/96 (52%), Gaps = 3/96 (3%) Frame = +2 Query: 299 EQYEVVEQIGRGAYGTAYLVHHKAERKRYVMK---KIRLTKQNDKFQRTAYQEMSLMASL 469 + ++ ++ IG+G G YLV K + Y MK K + K+N K +R A E ++A+ Sbjct: 240 QSFDKIKLIGKGDVGKVYLVKEKKSGRLYAMKVLSKKEMIKRN-KIKR-ALAEQEILATS 297 Query: 470 SNPYIVEYKDGWVDEGTSVCIVTSYCEGGDMAQRIK 577 ++P+IV + E + + YC GG+ + ++ Sbjct: 298 NHPFIVTLYHSFQSE-DYLYLCMEYCSGGEFFRALQ 332
>CDPK1_ARATH (Q06850) Calcium-dependent protein kinase, isoform AK1 (EC| 2.7.11.1) (CDPK) Length = 610 Score = 41.6 bits (96), Expect = 0.002 Identities = 28/100 (28%), Positives = 49/100 (49%), Gaps = 2/100 (2%) Frame = +2 Query: 281 KARNPMEQYEVVEQIGRGAYGTAYLVHHKAERKRYVMKKIRLTK-QNDKFQRTAYQEMSL 457 K N E Y + ++G+G +GT +L K K + K I K D+ +E+ + Sbjct: 142 KTENFKEFYSLGRKLGQGQFGTTFLCVEKTTGKEFACKSIAKRKLLTDEDVEDVRREIQI 201 Query: 458 MASLS-NPYIVEYKDGWVDEGTSVCIVTSYCEGGDMAQRI 574 M L+ +P ++ K G ++ +V +V C GG++ RI Sbjct: 202 MHHLAGHPNVISIK-GAYEDVVAVHLVMECCAGGELFDRI 240
>ATG1_CANGA (Q6FL58) Serine/threonine-protein kinase ATG1 (EC 2.7.11.1)| (Autophagy-related protein 1) Length = 942 Score = 41.6 bits (96), Expect = 0.002 Identities = 28/98 (28%), Positives = 48/98 (48%), Gaps = 5/98 (5%) Frame = +2 Query: 302 QYEVVEQIGRGAYGTAYLVHHKAERKRYVMKK--IRLTKQNDKFQRTAYQEMSLMASLSN 475 +Y V ++IG+G++ T Y H + K ++ K R +N K E++++ + + Sbjct: 10 KYVVEKEIGKGSFATVYRGHVTTDPKSHIAVKAVARSKLKNKKLLENLEIEIAILKKIKH 69 Query: 476 PYIVEYKDGWVD---EGTSVCIVTSYCEGGDMAQRIKK 580 P+IV G +D T +V YC GD+ IKK Sbjct: 70 PHIV----GLIDCERTTTDFYLVMDYCALGDLTFLIKK 103
>CDK7_MOUSE (Q03147) Cell division protein kinase 7 (EC 2.7.11.22) (EC| 2.7.11.23) (CDK-activating kinase) (CAK) (TFIIH basal transcription factor complex kinase subunit) (39 kDa protein kinase) (P39 Mo15) (Protein-tyrosine kinase MPK-7) (CR4 protein kinas Length = 346 Score = 41.6 bits (96), Expect = 0.002 Identities = 22/72 (30%), Positives = 39/72 (54%), Gaps = 3/72 (4%) Frame = +2 Query: 299 EQYEVVEQIGRGAYGTAYLVHHKAERKRYVMKKIRL---TKQNDKFQRTAYQEMSLMASL 469 ++YE ++ +G G + T Y K + +KKI+L ++ D RTA +E+ L+ L Sbjct: 10 KRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQEL 69 Query: 470 SNPYIVEYKDGW 505 S+P I+ D + Sbjct: 70 SHPNIIGLLDAF 81
>CDK7_HUMAN (P50613) Cell division protein kinase 7 (EC 2.7.11.22) (EC| 2.7.11.23) (CDK-activating kinase) (CAK) (TFIIH basal transcription factor complex kinase subunit) (39 kDa protein kinase) (P39 Mo15) (STK1) (CAK1) Length = 346 Score = 41.6 bits (96), Expect = 0.002 Identities = 22/72 (30%), Positives = 39/72 (54%), Gaps = 3/72 (4%) Frame = +2 Query: 299 EQYEVVEQIGRGAYGTAYLVHHKAERKRYVMKKIRL---TKQNDKFQRTAYQEMSLMASL 469 ++YE ++ +G G + T Y K + +KKI+L ++ D RTA +E+ L+ L Sbjct: 10 KRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQEL 69 Query: 470 SNPYIVEYKDGW 505 S+P I+ D + Sbjct: 70 SHPNIIGLLDAF 81
>KPK1_PHAVU (P15792) Protein kinase PVPK-1 (EC 2.7.11.1)| Length = 609 Score = 41.6 bits (96), Expect = 0.002 Identities = 25/90 (27%), Positives = 44/90 (48%), Gaps = 1/90 (1%) Frame = +2 Query: 296 MEQYEVVEQIGRGAYGTAYLVHHKAERKRYVMKKIRLTK-QNDKFQRTAYQEMSLMASLS 472 M + +++++G G G+ YL R + MK + T+ N K A E ++ SL Sbjct: 226 MRHFRLLKKLGCGDIGSVYLAELSGTRTSFAMKVMNKTELANRKKLLRAQTEREILQSLD 285 Query: 473 NPYIVEYKDGWVDEGTSVCIVTSYCEGGDM 562 +P++ + E S C+V +C GGD+ Sbjct: 286 HPFLPTLYTHFETEIFS-CLVMEFCPGGDL 314
>CDK5_DROME (P48609) Cell division protein kinase 5 homolog (EC 2.7.11.22)| Length = 294 Score = 41.6 bits (96), Expect = 0.002 Identities = 19/68 (27%), Positives = 39/68 (57%) Frame = +2 Query: 296 MEQYEVVEQIGRGAYGTAYLVHHKAERKRYVMKKIRLTKQNDKFQRTAYQEMSLMASLSN 475 M++Y+ +E+IG G YGT + ++ + +K++RL + ++ +A +E+ L+ L + Sbjct: 1 MQKYDKMEKIGEGTYGTVFKGRNRDTMEIVALKRVRLDEDDEGVPSSALREICLLKELKH 60 Query: 476 PYIVEYKD 499 IV D Sbjct: 61 KNIVRLID 68
>STE7_CANAL (P46599) Serine/threonine-protein kinase STE7 homolog (EC 2.7.12.2)| Length = 589 Score = 41.2 bits (95), Expect = 0.002 Identities = 35/183 (19%), Positives = 78/183 (42%), Gaps = 6/183 (3%) Frame = +2 Query: 32 DLDPPDPTHTERARRPLLSHFHTRAAAVHARSPLRDHHHQRRALPVSSPEHHRIIY---- 199 ++DP + T+ + S+ + H + HHH LP ++ + +I Sbjct: 157 NVDPDNVVSTDMILNQI-SNLDLTSMNHHRQHYQNSHHH----LPTTNRKRQTVISSISP 211 Query: 200 TRPAATASNSAPQDEHARARAKEQELGKARNPMEQYEVV--EQIGRGAYGTAYLVHHKAE 373 T+ +A +S PQ + A ++ + + +++ +Q+G G G+ + H Sbjct: 212 TKSSAASSPLEPQIQSLPASSQSPIATTSSLKLNNKDLLTLKQLGSGNSGSVSKILHIPT 271 Query: 374 RKRYVMKKIRLTKQNDKFQRTAYQEMSLMASLSNPYIVEYKDGWVDEGTSVCIVTSYCEG 553 +K K I + ++ Q +E+ ++ +PYI+E+ ++ ++ I YC Sbjct: 272 QKTMAKKIIHIDSKS-VIQTQIIRELRILHECHSPYIIEFYGACLNNNNTIVICMEYCNC 330 Query: 554 GDM 562 G + Sbjct: 331 GSL 333
>PAK1_YEAST (P38990) Serine/threonine-protein kinase PAK1 (EC 2.7.11.1)| Length = 1142 Score = 41.2 bits (95), Expect = 0.002 Identities = 32/164 (19%), Positives = 70/164 (42%), Gaps = 26/164 (15%) Frame = +2 Query: 149 QRRALPVSSPEHHRIIYTRPAATASNSAPQDEHARARAKEQELGKA---------RNPME 301 ++R ++ P+H + I + A T + ++ ++ K +E + R + Sbjct: 72 RQRVRQLNHPQHQQHISSSLAKTPTTTSSFCSSGSSKNKVKETNRISLTYDPVSKRKVLN 131 Query: 302 QYEVVEQIGRGAYGTAYLV----------------HHKAERKRYVMKKIRLTKQNDKFQR 433 YE+++++G G +G L H K +RK + K +NDK +R Sbjct: 132 TYEIIKELGHGQHGKVKLARDILSKQLVAIKIVDRHEKKQRKFFTFIKSSKISENDKIKR 191 Query: 434 TAYQEMSLMASLSNPYIVEYKDGWVD-EGTSVCIVTSYCEGGDM 562 E+++M + ++V+ + D + + +V YC G++ Sbjct: 192 ----EIAIMKKCHHKHVVQLIEVLDDLKSRKIYLVLEYCSRGEV 231
>TSSK4_HUMAN (Q6SA08) Testis-specific serine/threonine-protein kinase 4 (EC| 2.7.11.1) (TSSK-4) (Testis-specific kinase 4) (TSK-4) (Serine/threonine-protein kinase 22E) Length = 328 Score = 41.2 bits (95), Expect = 0.002 Identities = 23/93 (24%), Positives = 49/93 (52%), Gaps = 1/93 (1%) Frame = +2 Query: 305 YEVVEQIGRGAYGTAYLVHHKAERKRYVMKKIRLTKQNDKF-QRTAYQEMSLMASLSNPY 481 YEV + IG G+YG+ Y + ++ +K I K +D + + +E+ +M L + Y Sbjct: 25 YEVGKAIGHGSYGSVYEAFYTKQKVMVAVKIISKKKASDDYLNKFLPREIQVMKVLRHKY 84 Query: 482 IVEYKDGWVDEGTSVCIVTSYCEGGDMAQRIKK 580 ++ + ++ + V I+ +GGD+ + I++ Sbjct: 85 LINFYRA-IESTSRVYIILELAQGGDVLEWIQR 116
>CHK1_XENLA (Q6DE87) Serine/threonine-protein kinase Chk1 (EC 2.7.11.1) (xChk1| protein) Length = 474 Score = 41.2 bits (95), Expect = 0.002 Identities = 25/94 (26%), Positives = 47/94 (50%) Frame = +2 Query: 296 MEQYEVVEQIGRGAYGTAYLVHHKAERKRYVMKKIRLTKQNDKFQRTAYQEMSLMASLSN 475 +E +++V+ +G GAYG L ++ + +K + +T+ D +E+ + LS+ Sbjct: 6 VEDWDLVQTLGEGAYGEVQLAVNRKTEEAVAVKIVDMTRAAD-CPENIKKEICINRMLSH 64 Query: 476 PYIVEYKDGWVDEGTSVCIVTSYCEGGDMAQRIK 577 IV + G EG + YC GG++ RI+ Sbjct: 65 TNIVRFY-GHRREGNIQYLFLEYCRGGELFDRIE 97
>KAPC_DROME (P12370) cAMP-dependent protein kinase catalytic subunit (EC| 2.7.11.11) (PKA C) Length = 352 Score = 41.2 bits (95), Expect = 0.002 Identities = 29/115 (25%), Positives = 57/115 (49%), Gaps = 7/115 (6%) Frame = +2 Query: 257 RAKEQELGK-ARNP-----MEQYEVVEQIGRGAYGTAYLVHHKAERKRYVMKKIRLTK-Q 415 +AKE+ K RNP ++ +E ++ +G G++G +V HK + Y MK + K Sbjct: 23 QAKEEFEDKWRRNPTNTAALDDFERIKTLGTGSFGRVMIVQHKPTKDYYAMKILDKQKVV 82 Query: 416 NDKFQRTAYQEMSLMASLSNPYIVEYKDGWVDEGTSVCIVTSYCEGGDMAQRIKK 580 K E ++ ++ P++V + + D +++ +V Y GG+M ++K Sbjct: 83 KLKQVEHTLNEKRILQAIQFPFLVSLRYHFKD-NSNLYMVLEYVPGGEMFSHLRK 136
>E2AK4_HUMAN (Q9P2K8) Eukaryotic translation initiation factor 2-alpha kinase 4| (EC 2.7.11.1) (GCN2-like protein) Length = 1649 Score = 41.2 bits (95), Expect = 0.002 Identities = 19/70 (27%), Positives = 42/70 (60%) Frame = +2 Query: 302 QYEVVEQIGRGAYGTAYLVHHKAERKRYVMKKIRLTKQNDKFQRTAYQEMSLMASLSNPY 481 ++E ++ +G+GA+G V +K + Y +K+I + + +F+R E++L++ L + Sbjct: 589 EFEELQLLGKGAFGAVIKVQNKLDGCCYAVKRIPINPASRQFRRIK-GEVTLLSRLHHEN 647 Query: 482 IVEYKDGWVD 511 IV Y + W++ Sbjct: 648 IVRYYNAWIE 657
>ZYG1_CAEEL (Q9GT24) Probable serine/threonine-protein kinase zyg-1 (EC| 2.7.11.1) (Zygote defective protein 1) Length = 706 Score = 41.2 bits (95), Expect = 0.002 Identities = 26/102 (25%), Positives = 52/102 (50%), Gaps = 1/102 (0%) Frame = +2 Query: 278 GKARNPMEQYEVVEQIGRGAYGTAYLVHHKAERKRYVMKKIRLTKQNDKFQRTAYQEMSL 457 GK+ + + Y +++IG+G +G Y + K + R+ K+ K + E+ Sbjct: 4 GKSGSRLSAYSHLKEIGKGGFGVVYAAQRENGEKVAIK---RIDKKVPK--NRVWTEIQT 58 Query: 458 MASL-SNPYIVEYKDGWVDEGTSVCIVTSYCEGGDMAQRIKK 580 M L + Y+VE+ + +V++G + IV CEGG + +++ Sbjct: 59 MKELKKSKYVVEFYEDFVEDGYTY-IVMELCEGGSLQAYVRE 99
>KAPCG_MACMU (O62846) cAMP-dependent protein kinase, gamma-catalytic subunit (EC| 2.7.11.11) (PKA C-gamma) (Fragment) Length = 208 Score = 41.2 bits (95), Expect = 0.002 Identities = 23/95 (24%), Positives = 49/95 (51%), Gaps = 1/95 (1%) Frame = +2 Query: 299 EQYEVVEQIGRGAYGTAYLVHHKAERKRYVMKKIRLTK-QNDKFQRTAYQEMSLMASLSN 475 +Q+E ++ +G G+YG LV H+ Y MK + K K E ++ +++ Sbjct: 40 DQFERLKTLGTGSYGRVMLVRHRETGNHYAMKILDKQKVVRLKQVEHTLNEKRILQAINF 99 Query: 476 PYIVEYKDGWVDEGTSVCIVTSYCEGGDMAQRIKK 580 P++V+ + + D +++ +V Y GG+M +++ Sbjct: 100 PFLVKLQFSFKD-NSNLYLVMEYVPGGEMFSHLRR 133
>ATG1_USTMA (Q4P0K0) Serine/threonine-protein kinase ATG1 (EC 2.7.11.1)| (Autophagy-related protein 1) Length = 990 Score = 41.2 bits (95), Expect = 0.002 Identities = 23/92 (25%), Positives = 47/92 (51%) Frame = +2 Query: 305 YEVVEQIGRGAYGTAYLVHHKAERKRYVMKKIRLTKQNDKFQRTAYQEMSLMASLSNPYI 484 + + +IG+G++ + + R+ +K + K K E++++ ++ +P I Sbjct: 15 FVIENEIGKGSFAVVHKGYRLQPREPVAIKIVIRKKLTPKLLDNLEGEIAILKAIHHPNI 74 Query: 485 VEYKDGWVDEGTSVCIVTSYCEGGDMAQRIKK 580 VE K+ E + +V ++C GD+AQ IKK Sbjct: 75 VELKECLKTEH-QIYLVMAFCASGDLAQYIKK 105 Database: uniprot_sprot.fasta Posted date: May 25, 2006 5:36 PM Number of letters in database: 80,573,946 Number of sequences in database: 219,361 Lambda K H 0.318 0.135 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 68,163,523 Number of Sequences: 219361 Number of extensions: 1282541 Number of successful extensions: 6457 Number of sequences better than 10.0: 500 Number of HSP's better than 10.0 without gapping: 5890 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 6332 length of database: 80,573,946 effective HSP length: 106 effective length of database: 57,321,680 effective search space used: 4929664480 frameshift window, decay const: 50, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
