ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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| Clone Name | basd2j04 |
|---|---|
| Clone Library Name | barley_pub |
>BRI1_LYCPE (Q8L899) Systemin receptor SR160 precursor (EC 2.7.11.1)| (Brassinosteroid LRR receptor kinase) Length = 1207 Score = 107 bits (266), Expect = 4e-23 Identities = 61/172 (35%), Positives = 90/172 (52%) Frame = +1 Query: 82 KDAGFQSAEEGGSGTFRQGSTHGITAPSPLVGLPEFSYLGWGHWFTLRDLELATNRFSKD 261 K+A ++ +G S + S T+ + + ++ T DL ATN F D Sbjct: 832 KEAALEAYMDGHSHSATANSAWKFTSAREALSINLAAFEKPLRKLTFADLLEATNGFHND 891 Query: 262 NXXXXXXXXXXXXXXXXNGTPVAVKKLLNNLGQAEKEFRVEVEAIGHVRHKNLVRLLGYC 441 + +G+ VA+KKL++ GQ ++EF E+E IG ++H+NLV LLGYC Sbjct: 892 SLVGSGGFGDVYKAQLKDGSVVAIKKLIHVSGQGDREFTAEMETIGKIKHRNLVPLLGYC 951 Query: 442 VEGTQRILVYEYVNNGNLEQWLHGAMSHRGSLTWEARIKILLGTAKALAYLH 597 G +R+LVYEY+ G+LE LH L W AR KI +G A+ LA+LH Sbjct: 952 KVGEERLLVYEYMKYGSLEDVLHDRKKTGIKLNWPARRKIAIGAARGLAFLH 1003
>BRI1_LYCES (Q8GUQ5) Brassinosteroid LRR receptor kinase precursor (EC 2.7.11.1)| (tBRI1) (Altered brassinolide sensitivity 1) (Systemin receptor SR160) Length = 1207 Score = 106 bits (265), Expect = 5e-23 Identities = 61/172 (35%), Positives = 90/172 (52%) Frame = +1 Query: 82 KDAGFQSAEEGGSGTFRQGSTHGITAPSPLVGLPEFSYLGWGHWFTLRDLELATNRFSKD 261 K+A ++ +G S + S T+ + + ++ T DL ATN F D Sbjct: 832 KEAALEAYMDGHSHSATANSAWKFTSAREALSINLAAFEKPLRKLTFADLLEATNGFHND 891 Query: 262 NXXXXXXXXXXXXXXXXNGTPVAVKKLLNNLGQAEKEFRVEVEAIGHVRHKNLVRLLGYC 441 + +G+ VA+KKL++ GQ ++EF E+E IG ++H+NLV LLGYC Sbjct: 892 SLVGSGGFGDVYKAQLKDGSVVAIKKLIHVSGQGDREFTAEMETIGKIKHRNLVPLLGYC 951 Query: 442 VEGTQRILVYEYVNNGNLEQWLHGAMSHRGSLTWEARIKILLGTAKALAYLH 597 G +R+LVYEY+ G+LE LH L W AR KI +G A+ LA+LH Sbjct: 952 KVGEERLLVYEYMKYGSLEDVLHDRKKIGIKLNWPARRKIAIGAARGLAFLH 1003
>BRI1_ARATH (O22476) BRASSINOSTEROID INSENSITIVE 1 precursor (EC 2.7.11.1)| (AtBRI1) (Brassinosteroid LRR receptor kinase) Length = 1196 Score = 105 bits (262), Expect = 1e-22 Identities = 53/127 (41%), Positives = 74/127 (58%) Frame = +1 Query: 217 TLRDLELATNRFSKDNXXXXXXXXXXXXXXXXNGTPVAVKKLLNNLGQAEKEFRVEVEAI 396 T DL ATN F D+ +G+ VA+KKL++ GQ ++EF E+E I Sbjct: 872 TFADLLQATNGFHNDSLIGSGGFGDVYKAILKDGSAVAIKKLIHVSGQGDREFMAEMETI 931 Query: 397 GHVRHKNLVRLLGYCVEGTQRILVYEYVNNGNLEQWLHGAMSHRGSLTWEARIKILLGTA 576 G ++H+NLV LLGYC G +R+LVYE++ G+LE LH L W R KI +G+A Sbjct: 932 GKIKHRNLVPLLGYCKVGDERLLVYEFMKYGSLEDVLHDPKKAGVKLNWSTRRKIAIGSA 991 Query: 577 KALAYLH 597 + LA+LH Sbjct: 992 RGLAFLH 998
>PSKR_DAUCA (Q8LPB4) Phytosulfokine receptor precursor (EC 2.7.11.1)| (Phytosulfokine LRR receptor kinase) Length = 1021 Score = 104 bits (260), Expect = 2e-22 Identities = 49/131 (37%), Positives = 78/131 (59%) Frame = +1 Query: 217 TLRDLELATNRFSKDNXXXXXXXXXXXXXXXXNGTPVAVKKLLNNLGQAEKEFRVEVEAI 396 +L D+ +T+ F++ N +GT VA+K+L + GQ ++EF+ EVE + Sbjct: 732 SLDDILKSTSSFNQANIIGCGGFGLVYKATLPDGTKVAIKRLSGDTGQMDREFQAEVETL 791 Query: 397 GHVRHKNLVRLLGYCVEGTQRILVYEYVNNGNLEQWLHGAMSHRGSLTWEARIKILLGTA 576 +H NLV LLGYC ++L+Y Y++NG+L+ WLH + SL W+ R++I G A Sbjct: 792 SRAQHPNLVHLLGYCNYKNDKLLIYSYMDNGSLDYWLHEKVDGPPSLDWKTRLRIARGAA 851 Query: 577 KALAYLHEAIE 609 + LAYLH++ E Sbjct: 852 EGLAYLHQSCE 862
>BRL1_ARATH (Q9ZWC8) Serine/threonine-protein kinase BRI1-like 1 precursor (EC| 2.7.11.1) (BRASSINOSTEROID INSENSITIVE 1-like protein 1) Length = 1166 Score = 104 bits (260), Expect = 2e-22 Identities = 56/131 (42%), Positives = 76/131 (58%), Gaps = 2/131 (1%) Frame = +1 Query: 217 TLRDLELATNRFSKDNXXXXXXXXXXXXXXXXNGTPVAVKKLLNNLGQAEKEFRVEVEAI 396 T L ATN FS + +G+ VA+KKL+ GQ ++EF E+E I Sbjct: 848 TFAHLLEATNGFSAETMVGSGGFGEVYKAQLRDGSVVAIKKLIRITGQGDREFMAEMETI 907 Query: 397 GHVRHKNLVRLLGYCVEGTQRILVYEYVNNGNLEQWLHGAMSHRGS--LTWEARIKILLG 570 G ++H+NLV LLGYC G +R+LVYEY+ G+LE LH S +G L W AR KI +G Sbjct: 908 GKIKHRNLVPLLGYCKVGEERLLVYEYMKWGSLETVLHEKSSKKGGIYLNWAARKKIAIG 967 Query: 571 TAKALAYLHEA 603 A+ LA+LH + Sbjct: 968 AARGLAFLHHS 978
>BRL3_ARATH (Q9LJF3) Serine/threonine-protein kinase BRI1-like 3 precursor (EC| 2.7.11.1) (BRASSINOSTEROID INSENSITIVE 1-like protein 3) Length = 1164 Score = 103 bits (258), Expect = 3e-22 Identities = 56/130 (43%), Positives = 75/130 (57%), Gaps = 1/130 (0%) Frame = +1 Query: 217 TLRDLELATNRFSKDNXXXXXXXXXXXXXXXXNGTPVAVKKLLNNLGQAEKEFRVEVEAI 396 T L ATN FS D+ +G+ VA+KKL+ GQ ++EF E+E I Sbjct: 847 TFAHLLEATNGFSADSMIGSGGFGDVYKAKLADGSVVAIKKLIQVTGQGDREFMAEMETI 906 Query: 397 GHVRHKNLVRLLGYCVEGTQRILVYEYVNNGNLEQWLHGAMSHRG-SLTWEARIKILLGT 573 G ++H+NLV LLGYC G +R+LVYEY+ G+LE LH G L W AR KI +G Sbjct: 907 GKIKHRNLVPLLGYCKIGEERLLVYEYMKYGSLETVLHEKTKKGGIFLDWSARKKIAIGA 966 Query: 574 AKALAYLHEA 603 A+ LA+LH + Sbjct: 967 ARGLAFLHHS 976
>PSKR_ARATH (Q9ZVR7) Putative phytosulfokine receptor precursor (EC 2.7.11.1)| (Phytosulfokine LRR receptor kinase) Length = 1008 Score = 98.2 bits (243), Expect = 2e-20 Identities = 49/128 (38%), Positives = 67/128 (52%) Frame = +1 Query: 226 DLELATNRFSKDNXXXXXXXXXXXXXXXXNGTPVAVKKLLNNLGQAEKEFRVEVEAIGHV 405 DL +TN F + N +G VA+KKL + GQ E+EF EVE + Sbjct: 726 DLLDSTNSFDQANIIGCGGFGMVYKATLPDGKKVAIKKLSGDCGQIEREFEAEVETLSRA 785 Query: 406 RHKNLVRLLGYCVEGTQRILVYEYVNNGNLEQWLHGAMSHRGSLTWEARIKILLGTAKAL 585 +H NLV L G+C R+L+Y Y+ NG+L+ WLH L W+ R++I G AK L Sbjct: 786 QHPNLVLLRGFCFYKNDRLLIYSYMENGSLDYWLHERNDGPALLKWKTRLRIAQGAAKGL 845 Query: 586 AYLHEAIE 609 YLHE + Sbjct: 846 LYLHEGCD 853
>EXS_ARATH (Q9LYN8) Leucine-rich repeat receptor protein kinase EXS precursor| (EC 2.7.11.1) (Extra sporogenous cells protein) (EXCESS MICROSPOROCYTES1 protein) Length = 1192 Score = 95.9 bits (237), Expect = 8e-20 Identities = 51/126 (40%), Positives = 67/126 (53%) Frame = +1 Query: 220 LRDLELATNRFSKDNXXXXXXXXXXXXXXXXNGTPVAVKKLLNNLGQAEKEFRVEVEAIG 399 L D+ AT+ FSK N VAVKKL Q +EF E+E +G Sbjct: 907 LGDIVEATDHFSKKNIIGDGGFGTVYKACLPGEKTVAVKKLSEAKTQGNREFMAEMETLG 966 Query: 400 HVRHKNLVRLLGYCVEGTQRILVYEYVNNGNLEQWLHGAMSHRGSLTWEARIKILLGTAK 579 V+H NLV LLGYC +++LVYEY+ NG+L+ WL L W R+KI +G A+ Sbjct: 967 KVKHPNLVSLLGYCSFSEEKLLVYEYMVNGSLDHWLRNQTGMLEVLDWSKRLKIAVGAAR 1026 Query: 580 ALAYLH 597 LA+LH Sbjct: 1027 GLAFLH 1032
>BRL2_ARATH (Q9ZPS9) Serine/threonine-protein kinase BRI1-like 2 precursor (EC| 2.7.11.1) (BRASSINOSTEROID INSENSITIVE 1-like protein 2) (Protein VASCULAR HIGHWAY 1) Length = 1143 Score = 95.5 bits (236), Expect = 1e-19 Identities = 51/122 (41%), Positives = 71/122 (58%), Gaps = 2/122 (1%) Frame = +1 Query: 238 ATNRFSKDNXXXXXXXXXXXXXXXXNGTPVAVKKLLNNLGQAEKEFRVEVEAIGHVRHKN 417 ATN FS + +G+ VA+KKL+ Q ++EF E+E +G ++H+N Sbjct: 834 ATNGFSAASMIGHGGFGEVFKATLKDGSSVAIKKLIRLSCQGDREFMAEMETLGKIKHRN 893 Query: 418 LVRLLGYCVEGTQRILVYEYVNNGNLEQWLHGAMS--HRGSLTWEARIKILLGTAKALAY 591 LV LLGYC G +R+LVYE++ G+LE+ LHG + R L WE R KI G AK L + Sbjct: 894 LVPLLGYCKIGEERLLVYEFMQYGSLEEVLHGPRTGEKRRILGWEERKKIAKGAAKGLCF 953 Query: 592 LH 597 LH Sbjct: 954 LH 955
>BAK1_ARATH (Q94F62) BRASSINOSTEROID INSENSITIVE 1-associated receptor kinase 1| precursor (EC 2.7.11.1) (BRI1-associated receptor kinase 1) (Somatic embryogenesis receptor-like kinase 3) Length = 615 Score = 91.7 bits (226), Expect = 2e-18 Identities = 52/137 (37%), Positives = 77/137 (56%), Gaps = 1/137 (0%) Frame = +1 Query: 193 YLGWGHWFTLRDLELATNRFSKDNXXXXXXXXXXXXXXXXNGTPVAVKKLLNNLGQA-EK 369 +LG F+LR+L++A++ FS N +GT VAVK+L Q E Sbjct: 270 HLGQLKRFSLRELQVASDNFSNKNILGRGGFGKVYKGRLADGTLVAVKRLKEERTQGGEL 329 Query: 370 EFRVEVEAIGHVRHKNLVRLLGYCVEGTQRILVYEYVNNGNLEQWLHGAMSHRGSLTWEA 549 +F+ EVE I H+NL+RL G+C+ T+R+LVY Y+ NG++ L + L W Sbjct: 330 QFQTEVEMISMAVHRNLLRLRGFCMTPTERLLVYPYMANGSVASCLRERPESQPPLDWPK 389 Query: 550 RIKILLGTAKALAYLHE 600 R +I LG+A+ LAYLH+ Sbjct: 390 RQRIALGSARGLAYLHD 406
>PBS1_ARATH (Q9FE20) Serine/threonine-protein kinase PBS1 (EC 2.7.11.1)| (AvrPphB susceptible protein 1) Length = 456 Score = 91.3 bits (225), Expect = 2e-18 Identities = 61/172 (35%), Positives = 82/172 (47%), Gaps = 1/172 (0%) Frame = +1 Query: 88 AGFQSAEEGGSGTFRQGSTHGITAPSPLVGLPEFSYLGWGHWFTLRDLELATNRFSKDNX 267 +G S E S GS + P GL + + H F R+L AT F D Sbjct: 38 SGLPSGGEKLSSKTNGGSKRELLLPRD--GLGQIA----AHTFAFRELAAATMNFHPDTF 91 Query: 268 XXXXXXXXXXXXXXXN-GTPVAVKKLLNNLGQAEKEFRVEVEAIGHVRHKNLVRLLGYCV 444 + G VAVK+L N Q +EF VEV + + H NLV L+GYC Sbjct: 92 LGEGGFGRVYKGRLDSTGQVVAVKQLDRNGLQGNREFLVEVLMLSLLHHPNLVNLIGYCA 151 Query: 445 EGTQRILVYEYVNNGNLEQWLHGAMSHRGSLTWEARIKILLGTAKALAYLHE 600 +G QR+LVYE++ G+LE LH + +L W R+KI G AK L +LH+ Sbjct: 152 DGDQRLLVYEFMPLGSLEDHLHDLPPDKEALDWNMRMKIAAGAAKGLEFLHD 203
>APK1B_ARATH (P46573) Protein kinase APK1B, chloroplast precursor (EC 2.7.11.1)| Length = 412 Score = 87.4 bits (215), Expect = 3e-17 Identities = 50/140 (35%), Positives = 70/140 (50%), Gaps = 10/140 (7%) Frame = +1 Query: 214 FTLRDLELATNRFSKDNXXXXXXXXXX----------XXXXXXNGTPVAVKKLLNNLGQA 363 FT +L+ AT F D+ G +AVKKL + Q Sbjct: 57 FTFAELKAATRNFRPDSVLGEGGFGSVFKGWIDEQTLTASKPGTGVVIAVKKLNQDGWQG 116 Query: 364 EKEFRVEVEAIGHVRHKNLVRLLGYCVEGTQRILVYEYVNNGNLEQWLHGAMSHRGSLTW 543 +E+ EV +G H NLV+L+GYC+E R+LVYE++ G+LE L S+ L+W Sbjct: 117 HQEWLAEVNYLGQFSHPNLVKLIGYCLEDEHRLLVYEFMPRGSLENHLFRRGSYFQPLSW 176 Query: 544 EARIKILLGTAKALAYLHEA 603 R+K+ LG AK LA+LH A Sbjct: 177 TLRLKVALGAAKGLAFLHNA 196
>RLCK7_ARATH (Q9LQQ8) Probable serine/threonine-protein kinase RLCKVII (EC| 2.7.11.1) Length = 423 Score = 87.0 bits (214), Expect = 4e-17 Identities = 44/92 (47%), Positives = 58/92 (63%) Frame = +1 Query: 325 VAVKKLLNNLGQAEKEFRVEVEAIGHVRHKNLVRLLGYCVEGTQRILVYEYVNNGNLEQW 504 VA+K+L N Q +EF VEV + H NLV+L+G+C EG QR+LVYEY+ G+LE Sbjct: 129 VAIKQLDRNGVQGIREFVVEVLTLSLADHPNLVKLIGFCAEGDQRLLVYEYMPQGSLEDH 188 Query: 505 LHGAMSHRGSLTWEARIKILLGTAKALAYLHE 600 LH S + L W R+KI G A+ L YLH+ Sbjct: 189 LHVLPSGKKPLDWNTRMKIAAGAARGLEYLHD 220
>CRI4_MAIZE (O24585) Putative receptor protein kinase CRINKLY4 precursor (EC| 2.7.11.1) Length = 901 Score = 85.9 bits (211), Expect = 8e-17 Identities = 45/131 (34%), Positives = 77/131 (58%), Gaps = 3/131 (2%) Frame = +1 Query: 214 FTLRDLELATNRFSKDNXXXXXXXXXXXXXXXXNGTPVAVKKLL--NNLGQAEKEFRVEV 387 F+ +LE AT FS+D+ +GT VAVK+ + +++ ++ KEF E+ Sbjct: 493 FSYEELEQATGGFSEDSQVGKGSFSCVFKGILRDGTVVAVKRAIKASDVKKSSKEFHNEL 552 Query: 388 EAIGHVRHKNLVRLLGYCVEGTQRILVYEYVNNGNLEQWLHGAMSH-RGSLTWEARIKIL 564 + + + H +L+ LLGYC +G++R+LVYE++ +G+L Q LHG + + L W R+ I Sbjct: 553 DLLSRLNHAHLLNLLGYCEDGSERLLVYEFMAHGSLYQHLHGKDPNLKKRLNWARRVTIA 612 Query: 565 LGTAKALAYLH 597 + A+ + YLH Sbjct: 613 VQAARGIEYLH 623
>NORK_MEDTR (Q8L4H4) Nodulation receptor kinase precursor (EC 2.7.11.1) (Does| not make infections protein 2) (Symbiosis receptor-like kinase) (MtSYMRK) Length = 925 Score = 84.0 bits (206), Expect = 3e-16 Identities = 49/128 (38%), Positives = 68/128 (53%) Frame = +1 Query: 214 FTLRDLELATNRFSKDNXXXXXXXXXXXXXXXXNGTPVAVKKLLNNLGQAEKEFRVEVEA 393 FTL +E AT ++ +G VAVK + Q +EF E+ Sbjct: 586 FTLEYIEQATEQYK--TLIGEGGFGSVYRGTLDDGQEVAVKVRSSTSTQGTREFDNELNL 643 Query: 394 IGHVRHKNLVRLLGYCVEGTQRILVYEYVNNGNLEQWLHGAMSHRGSLTWEARIKILLGT 573 + ++H+NLV LLGYC E Q+ILVY +++NG+L L+G S R L W R+ I LG Sbjct: 644 LSAIQHENLVPLLGYCNEYDQQILVYPFMSNGSLLDRLYGEASKRKILDWPTRLSIALGA 703 Query: 574 AKALAYLH 597 A+ LAYLH Sbjct: 704 ARGLAYLH 711
>NORK_PEA (Q8LKZ1) Nodulation receptor kinase precursor (EC 2.7.11.1)| Length = 924 Score = 84.0 bits (206), Expect = 3e-16 Identities = 49/128 (38%), Positives = 68/128 (53%) Frame = +1 Query: 214 FTLRDLELATNRFSKDNXXXXXXXXXXXXXXXXNGTPVAVKKLLNNLGQAEKEFRVEVEA 393 FTL +ELAT ++ +G VAVK Q +EF E+ Sbjct: 585 FTLEYIELATEKYK--TLIGEGGFGSVYRGTLDDGQEVAVKVRSATSTQGTREFDNELNL 642 Query: 394 IGHVRHKNLVRLLGYCVEGTQRILVYEYVNNGNLEQWLHGAMSHRGSLTWEARIKILLGT 573 + ++H+NLV LLGYC E Q+ILVY +++NG+L L+G + R L W R+ I LG Sbjct: 643 LSAIQHENLVPLLGYCNEYDQQILVYPFMSNGSLLDRLYGEPAKRKILDWPTRLSIALGA 702 Query: 574 AKALAYLH 597 A+ LAYLH Sbjct: 703 ARGLAYLH 710
>KPRO_MAIZE (P17801) Putative receptor protein kinase ZmPK1 precursor (EC| 2.7.11.1) Length = 817 Score = 83.6 bits (205), Expect = 4e-16 Identities = 47/93 (50%), Positives = 59/93 (63%), Gaps = 2/93 (2%) Frame = +1 Query: 325 VAVKKLLNNLGQAEKEFRVEVEAIGHVRHKNLVRLLGYCVEGTQRILVYEYVNNGNLEQW 504 VAVKKL N+ Q ++ F+ E+ IG + H NLVR+ G+C EG+ R+LV EYV NG+L Sbjct: 559 VAVKKL-ENVRQGKEVFQAELSVIGRINHMNLVRIWGFCSEGSHRLLVSEYVENGSLANI 617 Query: 505 LHGAMSHRGS--LTWEARIKILLGTAKALAYLH 597 L S G+ L WE R I LG AK LAYLH Sbjct: 618 L---FSEGGNILLDWEGRFNIALGVAKGLAYLH 647
>TMK1_ARATH (P43298) Putative receptor protein kinase TMK1 precursor (EC| 2.7.11.1) Length = 942 Score = 83.2 bits (204), Expect = 5e-16 Identities = 46/131 (35%), Positives = 72/131 (54%), Gaps = 4/131 (3%) Frame = +1 Query: 217 TLRDLELATNRFSKDNXXXXXXXXXXXXXXXXNGTPVAVKKLLNNL--GQAEKEFRVEVE 390 +++ L TN FS DN +GT +AVK++ N + G+ EF+ E+ Sbjct: 577 SIQVLRSVTNNFSSDNILGSGGFGVVYKGELHDGTKIAVKRMENGVIAGKGFAEFKSEIA 636 Query: 391 AIGHVRHKNLVRLLGYCVEGTQRILVYEYVNNGNLEQWLHGAMSHRG--SLTWEARIKIL 564 + VRH++LV LLGYC++G +++LVYEY+ G L + L S G L W+ R+ + Sbjct: 637 VLTKVRHRHLVTLLGYCLDGNEKLLVYEYMPQGTLSRHLF-EWSEEGLKPLLWKQRLTLA 695 Query: 565 LGTAKALAYLH 597 L A+ + YLH Sbjct: 696 LDVARGVEYLH 706
>APK1A_ARATH (Q06548) Protein kinase APK1A, chloroplast precursor (EC 2.7.11.1)| Length = 410 Score = 82.8 bits (203), Expect = 7e-16 Identities = 40/96 (41%), Positives = 61/96 (63%) Frame = +1 Query: 316 GTPVAVKKLLNNLGQAEKEFRVEVEAIGHVRHKNLVRLLGYCVEGTQRILVYEYVNNGNL 495 G +AVKKL + Q +E+ EV +G H++LV+L+GYC+E R+LVYE++ G+L Sbjct: 100 GLVIAVKKLNQDGWQGHQEWLAEVNYLGQFSHRHLVKLIGYCLEDEHRLLVYEFMPRGSL 159 Query: 496 EQWLHGAMSHRGSLTWEARIKILLGTAKALAYLHEA 603 E L + L+W+ R+K+ LG AK LA+LH + Sbjct: 160 ENHLFRRGLYFQPLSWKLRLKVALGAAKGLAFLHSS 195
>SIRK_ARATH (O64483) Senescence-induced receptor-like serine/threonine-protein| kinase precursor (FLG22-induced receptor-like kinase 1) Length = 876 Score = 82.4 bits (202), Expect = 9e-16 Identities = 45/95 (47%), Positives = 55/95 (57%) Frame = +1 Query: 313 NGTPVAVKKLLNNLGQAEKEFRVEVEAIGHVRHKNLVRLLGYCVEGTQRILVYEYVNNGN 492 NG VAVK L Q KEFR EV+ + V H NL L+GYC E +L+YEY+ N N Sbjct: 594 NGEQVAVKVLSEESAQGYKEFRAEVDLLMRVHHTNLTSLVGYCNEINHMVLIYEYMANEN 653 Query: 493 LEQWLHGAMSHRGSLTWEARIKILLGTAKALAYLH 597 L +L G S L+WE R+KI L A+ L YLH Sbjct: 654 LGDYLAGKRSF--ILSWEERLKISLDAAQGLEYLH 686
>NAK_ARATH (P43293) Probable serine/threonine-protein kinase NAK (EC 2.7.11.1)| Length = 389 Score = 81.3 bits (199), Expect = 2e-15 Identities = 38/96 (39%), Positives = 59/96 (61%) Frame = +1 Query: 316 GTPVAVKKLLNNLGQAEKEFRVEVEAIGHVRHKNLVRLLGYCVEGTQRILVYEYVNNGNL 495 G +AVK+L Q +E+ E+ +G + H NLV+L+GYC+E R+LVYE++ G+L Sbjct: 100 GIVIAVKRLNQEGFQGHREWLAEINYLGQLDHPNLVKLIGYCLEEEHRLLVYEFMTRGSL 159 Query: 496 EQWLHGAMSHRGSLTWEARIKILLGTAKALAYLHEA 603 E L + L+W R+++ LG A+ LA+LH A Sbjct: 160 ENHLFRRGTFYQPLSWNTRVRMALGAARGLAFLHNA 195
>SRK6_BRAOE (Q09092) Putative serine/threonine-protein kinase receptor| precursor (EC 2.7.11.1) (S-receptor kinase) (SRK) Length = 849 Score = 81.3 bits (199), Expect = 2e-15 Identities = 44/121 (36%), Positives = 63/121 (52%) Frame = +1 Query: 238 ATNRFSKDNXXXXXXXXXXXXXXXXNGTPVAVKKLLNNLGQAEKEFRVEVEAIGHVRHKN 417 AT FS N +G +AVK+L Q EF EV I ++H N Sbjct: 524 ATENFSSCNKLGQGGFGIVYKGRLLDGKEIAVKRLSKTSVQGTDEFMNEVTLIARLQHIN 583 Query: 418 LVRLLGYCVEGTQRILVYEYVNNGNLEQWLHGAMSHRGSLTWEARIKILLGTAKALAYLH 597 LV++LG C+EG +++L+YEY+ N +L+ +L G + R L W R I G A+ L YLH Sbjct: 584 LVQVLGCCIEGDEKMLIYEYLENLSLDSYLFG-KTRRSKLNWNERFDITNGVARGLLYLH 642 Query: 598 E 600 + Sbjct: 643 Q 643
>CLV1_ARATH (Q9SYQ8) Receptor protein kinase CLAVATA1 precursor (EC 2.7.11.1)| Length = 980 Score = 80.9 bits (198), Expect = 3e-15 Identities = 39/96 (40%), Positives = 60/96 (62%), Gaps = 1/96 (1%) Frame = +1 Query: 313 NGTPVAVKKLLNN-LGQAEKEFRVEVEAIGHVRHKNLVRLLGYCVEGTQRILVYEYVNNG 489 N VA+K+L+ G+++ F E++ +G +RH+++VRLLGY +L+YEY+ NG Sbjct: 713 NNVDVAIKRLVGRGTGRSDHGFTAEIQTLGRIRHRHIVRLLGYVANKDTNLLLYEYMPNG 772 Query: 490 NLEQWLHGAMSHRGSLTWEARIKILLGTAKALAYLH 597 +L + LHG S G L WE R ++ + AK L YLH Sbjct: 773 SLGELLHG--SKGGHLQWETRHRVAVEAAKGLCYLH 806
>CX32_ARATH (P27450) Probable serine/threonine-protein kinase Cx32, chloroplast| precursor (EC 2.7.11.1) Length = 419 Score = 77.4 bits (189), Expect = 3e-14 Identities = 40/95 (42%), Positives = 59/95 (62%) Frame = +1 Query: 313 NGTPVAVKKLLNNLGQAEKEFRVEVEAIGHVRHKNLVRLLGYCVEGTQRILVYEYVNNGN 492 +G VA+K+L + Q E+R EV +G + H+NLV+LLGYC E + +LVYE++ G+ Sbjct: 117 SGMIVAIKRLNSESVQGFAEWRSEVNFLGMLSHRNLVKLLGYCREDKELLLVYEFMPKGS 176 Query: 493 LEQWLHGAMSHRGSLTWEARIKILLGTAKALAYLH 597 LE L W+ RIKI++G A+ LA+LH Sbjct: 177 LESHL---FRRNDPFPWDLRIKIVIGAARGLAFLH 208
>RLK5_ARATH (P47735) Receptor-like protein kinase 5 precursor (EC 2.7.11.1)| Length = 999 Score = 72.8 bits (177), Expect = 7e-13 Identities = 42/104 (40%), Positives = 57/104 (54%), Gaps = 10/104 (9%) Frame = +1 Query: 316 GTPVAVKKLLNNLGQAEKE----------FRVEVEAIGHVRHKNLVRLLGYCVEGTQRIL 465 G VAVKKL ++ + E F EVE +G +RHK++VRL C G ++L Sbjct: 705 GEVVAVKKLNKSVKGGDDEYSSDSLNRDVFAAEVETLGTIRHKSIVRLWCCCSSGDCKLL 764 Query: 466 VYEYVNNGNLEQWLHGAMSHRGSLTWEARIKILLGTAKALAYLH 597 VYEY+ NG+L LHG L W R++I L A+ L+YLH Sbjct: 765 VYEYMPNGSLADVLHGDRKGGVVLGWPERLRIALDAAEGLSYLH 808
>IRAK1_MOUSE (Q62406) Interleukin-1 receptor-associated kinase 1 (EC 2.7.11.1)| (IRAK-1) (IRAK) (Pelle-like protein kinase) (mPLK) Length = 710 Score = 70.1 bits (170), Expect = 5e-12 Identities = 38/98 (38%), Positives = 52/98 (53%), Gaps = 4/98 (4%) Frame = +1 Query: 319 TPVAVKKLLNNLG----QAEKEFRVEVEAIGHVRHKNLVRLLGYCVEGTQRILVYEYVNN 486 T AVK+L ++ F EVE + RH N+V GYC E LVY ++ N Sbjct: 234 TTYAVKRLKEEADLEWTMVKQSFLTEVEQLSRFRHPNIVDFAGYCAESGLYCLVYGFLPN 293 Query: 487 GNLEQWLHGAMSHRGSLTWEARIKILLGTAKALAYLHE 600 G+LE LH L+W R+ ILLGTA+A+ +LH+ Sbjct: 294 GSLEDQLHLQTQACSPLSWPQRLDILLGTARAIQFLHQ 331
>IRAK1_HUMAN (P51617) Interleukin-1 receptor-associated kinase 1 (EC 2.7.11.1)| (IRAK-1) Length = 712 Score = 69.3 bits (168), Expect = 8e-12 Identities = 38/98 (38%), Positives = 53/98 (54%), Gaps = 4/98 (4%) Frame = +1 Query: 319 TPVAVKKLLNNLG----QAEKEFRVEVEAIGHVRHKNLVRLLGYCVEGTQRILVYEYVNN 486 T AVK+L N ++ F EVE + RH N+V GYC + LVY ++ N Sbjct: 234 TVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPN 293 Query: 487 GNLEQWLHGAMSHRGSLTWEARIKILLGTAKALAYLHE 600 G+LE LH L+W R+ ILLGTA+A+ +LH+ Sbjct: 294 GSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQ 331
>IRAK4_HUMAN (Q9NWZ3) Interleukin-1 receptor-associated kinase 4 (EC 2.7.11.1)| (IRAK-4) (NY-REN-64 antigen) Length = 460 Score = 60.8 bits (146), Expect = 3e-09 Identities = 36/100 (36%), Positives = 54/100 (54%), Gaps = 4/100 (4%) Frame = +1 Query: 313 NGTPVAVKKLLNNLG----QAEKEFRVEVEAIGHVRHKNLVRLLGYCVEGTQRILVYEYV 480 N T VAVKKL + + +++F E++ + +H+NLV LLG+ +G LVY Y+ Sbjct: 206 NNTTVAVKKLAAMVDITTEELKQQFDQEIKVMAKCQHENLVELLGFSSDGDDLCLVYVYM 265 Query: 481 NNGNLEQWLHGAMSHRGSLTWEARIKILLGTAKALAYLHE 600 NG+L L + L+W R KI G A + +LHE Sbjct: 266 PNGSLLDRL-SCLDGTPPLSWHMRCKIAQGAANGINFLHE 304
>IRAK4_MOUSE (Q8R4K2) Interleukin-1 receptor-associated kinase 4 (EC 2.7.11.1)| (IRAK-4) Length = 459 Score = 60.1 bits (144), Expect = 5e-09 Identities = 41/140 (29%), Positives = 64/140 (45%), Gaps = 9/140 (6%) Frame = +1 Query: 208 HWFTLRDLELATNRFSKDNXXXXXXXXXXXXXXXX-----NGTPVAVKKLLN----NLGQ 360 H F+ +L+ TN F + N T VAVKKL + + Sbjct: 166 HSFSFHELKSITNNFDEQPASAGGNRMGEGGFGVVYKGCVNNTIVAVKKLGAMVEISTEE 225 Query: 361 AEKEFRVEVEAIGHVRHKNLVRLLGYCVEGTQRILVYEYVNNGNLEQWLHGAMSHRGSLT 540 +++F E++ + +H+NLV LLG+ + LVY Y+ NG+L L + L+ Sbjct: 226 LKQQFDQEIKVMATCQHENLVELLGFSSDSDNLCLVYAYMPNGSLLDRL-SCLDGTPPLS 284 Query: 541 WEARIKILLGTAKALAYLHE 600 W R K+ GTA + +LHE Sbjct: 285 WHTRCKVAQGTANGIRFLHE 304
>KPEL_DROME (Q05652) Probable serine/threonine-protein kinase pelle (EC| 2.7.11.1) Length = 501 Score = 59.7 bits (143), Expect = 6e-09 Identities = 29/76 (38%), Positives = 47/76 (61%), Gaps = 2/76 (2%) Frame = +1 Query: 382 EVEAIGHVRHKNLVRLLGYCVEGTQRILVYEYVNNGNLEQWL--HGAMSHRGSLTWEARI 555 E++ + +RH N++ L GY ++G + LVY+ + G+LE L H A + +LTW+ R Sbjct: 262 ELKYLNSIRHDNILALYGYSIKGGKPCLVYQLMKGGSLEARLRAHKAQNPLPALTWQQRF 321 Query: 556 KILLGTAKALAYLHEA 603 I LGTA+ + +LH A Sbjct: 322 SISLGTARGIYFLHTA 337
>RPK1_IPONI (P93194) Receptor-like protein kinase precursor (EC 2.7.11.1)| Length = 1109 Score = 59.3 bits (142), Expect = 8e-09 Identities = 34/91 (37%), Positives = 49/91 (53%), Gaps = 1/91 (1%) Frame = +1 Query: 328 AVKKLL-NNLGQAEKEFRVEVEAIGHVRHKNLVRLLGYCVEGTQRILVYEYVNNGNLEQW 504 AVKKL+ + E+E IG VRH+NL++L + + +++Y Y+ NG+L Sbjct: 842 AVKKLVFTGIKNGSVSMVREIETIGKVRHRNLIKLEEFWLRKEYGLILYTYMENGSLHDI 901 Query: 505 LHGAMSHRGSLTWEARIKILLGTAKALAYLH 597 LH + L W R I +GTA LAYLH Sbjct: 902 LHETNPPK-PLDWSTRHNIAVGTAHGLAYLH 931
>TMKL1_ARATH (P33543) Putative kinase-like protein TMKL1 precursor| Length = 674 Score = 57.0 bits (136), Expect = 4e-08 Identities = 29/76 (38%), Positives = 45/76 (59%), Gaps = 1/76 (1%) Frame = +1 Query: 385 VEAIGHVRHKNLVRLLG-YCVEGTQRILVYEYVNNGNLEQWLHGAMSHRGSLTWEARIKI 561 + +G +RH+NLV L Y + +++L+Y+Y+ N +L LH + + +L W R KI Sbjct: 418 IRQLGRIRHENLVPLRAFYQGKRGEKLLIYDYLPNISLHDLLHESKPRKPALNWARRHKI 477 Query: 562 LLGTAKALAYLHEAIE 609 LG A+ LAYLH E Sbjct: 478 ALGIARGLAYLHTGQE 493
>TESK2_HUMAN (Q96S53) Dual specificity testis-specific protein kinase 2 (EC| 2.7.12.1) (Testicular protein kinase 2) Length = 571 Score = 57.0 bits (136), Expect = 4e-08 Identities = 32/95 (33%), Positives = 49/95 (51%) Frame = +1 Query: 313 NGTPVAVKKLLNNLGQAEKEFRVEVEAIGHVRHKNLVRLLGYCVEGTQRILVYEYVNNGN 492 +G +A+K +N L EV+ + + H N++R +G CV Q + EY+N+GN Sbjct: 80 SGQVMALK--MNTLSSNRANMLKEVQLMNRLSHPNILRFMGVCVHQGQLHALTEYINSGN 137 Query: 493 LEQWLHGAMSHRGSLTWEARIKILLGTAKALAYLH 597 LEQ L + L W R+K+ A L+YLH Sbjct: 138 LEQLLDSNL----HLPWTVRVKLAYDIAVGLSYLH 168
>TESK2_RAT (Q924U5) Dual specificity testis-specific protein kinase 2 (EC| 2.7.12.1) (Testicular protein kinase 2) Length = 570 Score = 55.5 bits (132), Expect = 1e-07 Identities = 31/95 (32%), Positives = 49/95 (51%) Frame = +1 Query: 313 NGTPVAVKKLLNNLGQAEKEFRVEVEAIGHVRHKNLVRLLGYCVEGTQRILVYEYVNNGN 492 +G +A+K +N L E++ + + H N++R +G CV Q + EY+N+GN Sbjct: 80 SGQVMALK--MNTLSSNRANLLKEMQLMNRLSHPNILRFMGVCVHQGQLHALTEYINSGN 137 Query: 493 LEQWLHGAMSHRGSLTWEARIKILLGTAKALAYLH 597 LEQ L + L W R+K+ A L+YLH Sbjct: 138 LEQLLDSNL----YLPWTVRVKLAYDIAVGLSYLH 168
>TESK2_MOUSE (Q8VCT9) Dual specificity testis-specific protein kinase 2 (EC| 2.7.12.1) (Testicular protein kinase 2) Length = 570 Score = 55.5 bits (132), Expect = 1e-07 Identities = 31/95 (32%), Positives = 49/95 (51%) Frame = +1 Query: 313 NGTPVAVKKLLNNLGQAEKEFRVEVEAIGHVRHKNLVRLLGYCVEGTQRILVYEYVNNGN 492 +G +A+K +N L E++ + + H N++R +G CV Q + EY+N+GN Sbjct: 80 SGQVMALK--MNTLSSNRANLLKEMQLMNRLSHPNILRFMGVCVHQGQLHALTEYINSGN 137 Query: 493 LEQWLHGAMSHRGSLTWEARIKILLGTAKALAYLH 597 LEQ L + L W R+K+ A L+YLH Sbjct: 138 LEQLLDSDL----YLPWTVRVKLAYDIAVGLSYLH 168
>TRK1_LYMST (O76997) Putative neurotrophin receptor LTRK 1 precursor (EC| 2.7.10.1) Length = 794 Score = 54.7 bits (130), Expect = 2e-07 Identities = 34/104 (32%), Positives = 54/104 (51%), Gaps = 14/104 (13%) Frame = +1 Query: 325 VAVKKLLNNLGQA-EKEFRVEVEAIGHVRHKNLVRLLGYCVEGTQRILVYEYVNNGNLEQ 501 VAVK L + + +++F E E + + H N+V G C E Q ++++E++ NG+L + Sbjct: 535 VAVKTLKGSCSDSLKRDFEREAEMLATIEHANIVTFYGVCTESDQWMMIFEFMENGDLNK 594 Query: 502 WL--HG-----------AMSHRGSLTWEARIKILLGTAKALAYL 594 +L HG S G LT E +KI+L A A+ YL Sbjct: 595 YLRMHGPDAAFLKDRDSMDSDEGQLTREQLMKIVLQIASAMEYL 638
>TESK1_HUMAN (Q15569) Dual specificity testis-specific protein kinase 1 (EC| 2.7.12.1) (Testicular protein kinase 1) Length = 626 Score = 54.7 bits (130), Expect = 2e-07 Identities = 32/89 (35%), Positives = 47/89 (52%) Frame = +1 Query: 331 VKKLLNNLGQAEKEFRVEVEAIGHVRHKNLVRLLGYCVEGTQRILVYEYVNNGNLEQWLH 510 + KL +N G +E V+ + +RH N++R +G CV Q + EY+N G LEQ L Sbjct: 87 MNKLPSNRGNTLRE----VQLMNRLRHPNILRFMGVCVHQGQLHALTEYMNGGTLEQLL- 141 Query: 511 GAMSHRGSLTWEARIKILLGTAKALAYLH 597 S L+W R+ + L A+ L YLH Sbjct: 142 ---SSPEPLSWPVRLHLALDIARGLRYLH 167
>VAB1_CAEEL (O61460) Ephrin receptor 1 precursor (EC 2.7.10.1) (Tyrosine-protein| kinase Eph receptor) (Variable abnormal protein 1) Length = 1122 Score = 53.9 bits (128), Expect = 4e-07 Identities = 29/91 (31%), Positives = 48/91 (52%), Gaps = 1/91 (1%) Frame = +1 Query: 325 VAVKKLLN-NLGQAEKEFRVEVEAIGHVRHKNLVRLLGYCVEGTQRILVYEYVNNGNLEQ 501 VA+K L + + +A+ EF E +G H N++RL+G ++V EY+ NG+L+Q Sbjct: 745 VAIKTLKSGSSAKAKAEFLTEATIMGQFSHPNVIRLIGVVTSAEPVMIVAEYMANGSLDQ 804 Query: 502 WLHGAMSHRGSLTWEARIKILLGTAKALAYL 594 +L + WE ++L G A + YL Sbjct: 805 FLRNTDQRGEKVHWEKITEMLYGIASGMKYL 835
>TESK1_RAT (Q63572) Dual specificity testis-specific protein kinase 1 (EC| 2.7.12.1) (Testicular protein kinase 1) Length = 628 Score = 53.9 bits (128), Expect = 4e-07 Identities = 30/85 (35%), Positives = 43/85 (50%) Frame = +1 Query: 343 LNNLGQAEKEFRVEVEAIGHVRHKNLVRLLGYCVEGTQRILVYEYVNNGNLEQWLHGAMS 522 +N L EV+ + +RH N++R +G CV Q + EY+N G LEQ L S Sbjct: 82 MNKLPSNRSNTLREVQLMNRLRHPNILRFMGVCVHQGQLHALTEYMNGGTLEQLL----S 137 Query: 523 HRGSLTWEARIKILLGTAKALAYLH 597 L+W R+ + L A+ L YLH Sbjct: 138 SPEPLSWPVRLHLALDIAQGLRYLH 162
>TESK1_MOUSE (O70146) Dual specificity testis-specific protein kinase 1 (EC| 2.7.12.1) (Testicular protein kinase 1) Length = 627 Score = 53.9 bits (128), Expect = 4e-07 Identities = 30/85 (35%), Positives = 43/85 (50%) Frame = +1 Query: 343 LNNLGQAEKEFRVEVEAIGHVRHKNLVRLLGYCVEGTQRILVYEYVNNGNLEQWLHGAMS 522 +N L EV+ + +RH N++R +G CV Q + EY+N G LEQ L S Sbjct: 82 MNKLPSNRSNTLREVQLMNRLRHPNILRFMGVCVHQGQLHALTEYMNGGTLEQLL----S 137 Query: 523 HRGSLTWEARIKILLGTAKALAYLH 597 L+W R+ + L A+ L YLH Sbjct: 138 SPEPLSWPVRLHLALDIAQGLRYLH 162
>NTRK2_HUMAN (Q16620) BDNF/NT-3 growth factors receptor precursor (EC 2.7.10.1)| (Neurotrophic tyrosine kinase receptor type 2) (TrkB tyrosine kinase) (GP145-TrkB) (Trk-B) Length = 822 Score = 53.5 bits (127), Expect = 5e-07 Identities = 26/65 (40%), Positives = 43/65 (66%), Gaps = 2/65 (3%) Frame = +1 Query: 325 VAVKKLLNNLGQAEKEFRVEVEAIGHVRHKNLVRLLGYCVEGTQRILVYEYVNNGNLEQW 504 VAVK L + A K+F E E + +++H+++V+ G CVEG I+V+EY+ +G+L ++ Sbjct: 569 VAVKTLKDASDNARKDFHREAELLTNLQHEHIVKFYGVCVEGDPLIMVFEYMKHGDLNKF 628 Query: 505 L--HG 513 L HG Sbjct: 629 LRAHG 633
>NTRK2_RAT (Q63604) BDNF/NT-3 growth factors receptor precursor (EC 2.7.10.1)| (Neurotrophic tyrosine kinase receptor type 2) (TrkB tyrosine kinase) (GP145-TrkB/GP95-TrkB) (Trk-B) Length = 821 Score = 53.5 bits (127), Expect = 5e-07 Identities = 26/65 (40%), Positives = 43/65 (66%), Gaps = 2/65 (3%) Frame = +1 Query: 325 VAVKKLLNNLGQAEKEFRVEVEAIGHVRHKNLVRLLGYCVEGTQRILVYEYVNNGNLEQW 504 VAVK L + A K+F E E + +++H+++V+ G CVEG I+V+EY+ +G+L ++ Sbjct: 568 VAVKTLKDASDNARKDFHREAELLTNLQHEHIVKFYGVCVEGDPLIMVFEYMKHGDLNKF 627 Query: 505 L--HG 513 L HG Sbjct: 628 LRAHG 632
>NTRK2_MOUSE (P15209) BDNF/NT-3 growth factors receptor precursor (EC 2.7.10.1)| (Neurotrophic tyrosine kinase receptor type 2) (TrkB tyrosine kinase) (GP145-TrkB/GP95-TrkB) (Trk-B) Length = 821 Score = 53.5 bits (127), Expect = 5e-07 Identities = 26/65 (40%), Positives = 43/65 (66%), Gaps = 2/65 (3%) Frame = +1 Query: 325 VAVKKLLNNLGQAEKEFRVEVEAIGHVRHKNLVRLLGYCVEGTQRILVYEYVNNGNLEQW 504 VAVK L + A K+F E E + +++H+++V+ G CVEG I+V+EY+ +G+L ++ Sbjct: 568 VAVKTLKDASDNARKDFHREAELLTNLQHEHIVKFYGVCVEGDPLIMVFEYMKHGDLNKF 627 Query: 505 L--HG 513 L HG Sbjct: 628 LRAHG 632
>NTRK2_CHICK (Q91987) BDNF/NT-3 growth factors receptor precursor (EC 2.7.10.1)| (Neurotrophic tyrosine kinase receptor type 2) (TrkB tyrosine kinase) (Trk-B) Length = 818 Score = 53.5 bits (127), Expect = 5e-07 Identities = 26/65 (40%), Positives = 43/65 (66%), Gaps = 2/65 (3%) Frame = +1 Query: 325 VAVKKLLNNLGQAEKEFRVEVEAIGHVRHKNLVRLLGYCVEGTQRILVYEYVNNGNLEQW 504 VAVK L + A K+F E E + +++H+++V+ G CVEG I+V+EY+ +G+L ++ Sbjct: 565 VAVKTLKDASDNARKDFHREAELLTNLQHEHIVKFYGVCVEGDPLIMVFEYMKHGDLNKF 624 Query: 505 L--HG 513 L HG Sbjct: 625 LRAHG 629
>PTK7_CHICK (Q91048) Tyrosine-protein kinase-like 7 precursor (Kinase-like| protein) Length = 1051 Score = 53.5 bits (127), Expect = 5e-07 Identities = 36/94 (38%), Positives = 48/94 (51%), Gaps = 3/94 (3%) Frame = +1 Query: 325 VAVKKLLNNLGQAEKEFRVEVEAIGHVRHKNLVRLLGYCVEGTQRILVYEYVNNGNLEQW 504 V VK L Q + +FR E E G + H N+VRLLG C E +V EYV+ G+L+Q+ Sbjct: 808 VLVKSLQTRDEQLQLDFRREAEMFGKLNHVNVVRLLGLCREAEPHYMVLEYVDLGDLKQF 867 Query: 505 LHGAMSHRGSL---TWEARIKILLGTAKALAYLH 597 L + S SL + K+ L T AL H Sbjct: 868 LRISKSKDESLKPQPLSTKHKVSLCTQVALGMEH 901
>IRAK3_MOUSE (Q8K4B2) Interleukin-1 receptor-associated kinase 3 (EC 2.7.11.1)| (IRAK-3) (IL-1 receptor-associated kinase M) (IRAK-M) Length = 609 Score = 53.5 bits (127), Expect = 5e-07 Identities = 29/77 (37%), Positives = 42/77 (54%) Frame = +1 Query: 367 KEFRVEVEAIGHVRHKNLVRLLGYCVEGTQRILVYEYVNNGNLEQWLHGAMSHRGSLTWE 546 K F E+E + RH +++ L Y E + LVY Y++NG L L + L+W Sbjct: 220 KRFLSELEVLLLFRHPHILELAAYFTETEKLCLVYPYMSNGTLFDRLQ-CTNGTTPLSWH 278 Query: 547 ARIKILLGTAKALAYLH 597 RI +L+G AKA+ YLH Sbjct: 279 VRISVLIGIAKAIQYLH 295
>YR831_MIMIV (Q7T6Y2) Putative serine/threonine-protein kinase/receptor R831| precursor (EC 2.7.11.1) Length = 1624 Score = 52.4 bits (124), Expect = 1e-06 Identities = 31/98 (31%), Positives = 51/98 (52%), Gaps = 2/98 (2%) Frame = +1 Query: 316 GTPVAVKKLLNN-LGQAEK-EFRVEVEAIGHVRHKNLVRLLGYCVEGTQRILVYEYVNNG 489 G VAVKK + L + + EFR E+ + ++H N+V +G C++ +V EY+ G Sbjct: 1385 GVDVAVKKFVKQKLSETQLLEFRAEMAFLSELKHSNIVTFIGACIKKPNICIVTEYMRMG 1444 Query: 490 NLEQWLHGAMSHRGSLTWEARIKILLGTAKALAYLHEA 603 NL L +T+ ++K+L G A + YLH + Sbjct: 1445 NLRDVLKNPDI---KITFANKLKLLYGAAMGIDYLHSS 1479
>PTK7_HUMAN (Q13308) Tyrosine-protein kinase-like 7 precursor (Colon carcinoma| kinase 4) (CCK-4) Length = 1070 Score = 51.6 bits (122), Expect = 2e-06 Identities = 35/96 (36%), Positives = 50/96 (52%), Gaps = 3/96 (3%) Frame = +1 Query: 319 TPVAVKKLLNNLGQAEKEFRVEVEAIGHVRHKNLVRLLGYCVEGTQRILVYEYVNNGNLE 498 T V VK L + Q + +FR E+E G + H N+VRLLG C E +V EYV+ +L+ Sbjct: 825 TLVLVKSLQSKDEQQQLDFRRELEMFGKLNHANVVRLLGLCREAEPHYMVLEYVDLEDLK 884 Query: 499 QWLHGAMSHRGSLTWE---ARIKILLGTAKALAYLH 597 Q+L + S L + + K+ L T AL H Sbjct: 885 QFLRISKSKDEKLKSQPLSTKQKVALCTQVALGMEH 920
>IRAK3_HUMAN (Q9Y616) Interleukin-1 receptor-associated kinase 3 (EC 2.7.11.1)| (IRAK-3) (IL-1 receptor-associated kinase M) (IRAK-M) Length = 596 Score = 50.8 bits (120), Expect = 3e-06 Identities = 28/77 (36%), Positives = 39/77 (50%) Frame = +1 Query: 367 KEFRVEVEAIGHVRHKNLVRLLGYCVEGTQRILVYEYVNNGNLEQWLHGAMSHRGSLTWE 546 K F E+E + H N++ L Y E + L+Y Y+ NG L L + L W Sbjct: 207 KRFLSELEVLLLFHHPNILELAAYFTETEKFCLIYPYMRNGTLFDRLQ-CVGDTAPLPWH 265 Query: 547 ARIKILLGTAKALAYLH 597 RI IL+G +KA+ YLH Sbjct: 266 IRIGILIGISKAIHYLH 282
>IRAK2_HUMAN (O43187) Interleukin-1 receptor-associated kinase-like 2 (IRAK-2)| Length = 590 Score = 50.1 bits (118), Expect = 5e-06 Identities = 30/99 (30%), Positives = 47/99 (47%), Gaps = 4/99 (4%) Frame = +1 Query: 313 NGTPVAVKKL----LNNLGQAEKEFRVEVEAIGHVRHKNLVRLLGYCVEGTQRILVYEYV 480 +G P KKL ++ G E+ F+ E++ H N++ +LG+C +Y Y+ Sbjct: 230 HGKPFVFKKLRETACSSPGSIERFFQAELQICLRCCHPNVLPVLGFCAARQFHSFIYPYM 289 Query: 481 NNGNLEQWLHGAMSHRGSLTWEARIKILLGTAKALAYLH 597 NG+L+ L G L W R+ I G A+ YLH Sbjct: 290 ANGSLQDRLQG-QGGSDPLPWPQRVSICSGLLCAVEYLH 327
>NTRK1_HUMAN (P04629) High affinity nerve growth factor receptor precursor (EC| 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 1) (TRK1 transforming tyrosine kinase protein) (p140-TrkA) (Trk-A) Length = 796 Score = 49.7 bits (117), Expect = 7e-06 Identities = 24/65 (36%), Positives = 41/65 (63%), Gaps = 2/65 (3%) Frame = +1 Query: 325 VAVKKLLNNLGQAEKEFRVEVEAIGHVRHKNLVRLLGYCVEGTQRILVYEYVNNGNLEQW 504 VAVK L A ++F+ E E + ++H+++VR G C EG ++V+EY+ +G+L ++ Sbjct: 541 VAVKALKEASESARQDFQREAELLTMLQHQHIVRFFGVCTEGRPLLMVFEYMRHGDLNRF 600 Query: 505 L--HG 513 L HG Sbjct: 601 LRSHG 605
>NTRK1_RAT (P35739) High affinity nerve growth factor receptor precursor (EC| 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 1) (p140-TrkA) (Slow nerve growth factor receptor) (Trk-A) Length = 799 Score = 49.7 bits (117), Expect = 7e-06 Identities = 24/65 (36%), Positives = 40/65 (61%), Gaps = 2/65 (3%) Frame = +1 Query: 325 VAVKKLLNNLGQAEKEFRVEVEAIGHVRHKNLVRLLGYCVEGTQRILVYEYVNNGNLEQW 504 VAVK L A ++F E E + ++H+++VR G C EG ++V+EY+ +G+L ++ Sbjct: 544 VAVKALKETSENARQDFHREAELLTMLQHQHIVRFFGVCTEGGPLLMVFEYMRHGDLNRF 603 Query: 505 L--HG 513 L HG Sbjct: 604 LRSHG 608
>NTRK1_CHICK (Q91009) High affinity nerve growth factor receptor precursor (EC| 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 1) (Trk-A) (Fragment) Length = 778 Score = 49.3 bits (116), Expect = 9e-06 Identities = 31/103 (30%), Positives = 50/103 (48%), Gaps = 11/103 (10%) Frame = +1 Query: 319 TPVAVKKLLNNLGQAEKEFRVEVEAIGHVRHKNLVRLLGYCVEGTQRILVYEYVNNGNLE 498 T VAVK L A +F+ E E + ++H+++V+ G C EG I+V+EY+ +G+L Sbjct: 522 TLVAVKALKEVTENARLDFQREAELLTVLQHEHIVKFYGVCTEGDPLIMVFEYMKHGDLN 581 Query: 499 QWL-----------HGAMSHRGSLTWEARIKILLGTAKALAYL 594 ++L G G LT ++I A + YL Sbjct: 582 RFLRSHGPDAKILDQGQGQPCGQLTLSHMLQIATQIASGMVYL 624
>NTRK3_CHICK (Q91044) NT-3 growth factor receptor precursor (EC 2.7.10.1)| (Neurotrophic tyrosine kinase receptor type 3) (TrkC tyrosine kinase) (Trk-C) Length = 827 Score = 48.9 bits (115), Expect = 1e-05 Identities = 24/65 (36%), Positives = 43/65 (66%), Gaps = 2/65 (3%) Frame = +1 Query: 325 VAVKKLLNNLGQAEKEFRVEVEAIGHVRHKNLVRLLGYCVEGTQRILVYEYVNNGNLEQW 504 VAVK L + A K+F+ E E + +++H+++V+ G C +G I+V+EY+ +G+L ++ Sbjct: 571 VAVKALKDPTLAARKDFQREAELLTNLQHEHIVKFYGVCGDGDPLIMVFEYMKHGDLNKF 630 Query: 505 L--HG 513 L HG Sbjct: 631 LRAHG 635
>M3LK7_DROME (P83104) Putative mitogen-activated protein kinase kinase kinase| 7-like (EC 2.7.11.25) Length = 393 Score = 48.9 bits (115), Expect = 1e-05 Identities = 25/78 (32%), Positives = 43/78 (55%) Frame = +1 Query: 364 EKEFRVEVEAIGHVRHKNLVRLLGYCVEGTQRILVYEYVNNGNLEQWLHGAMSHRGSLTW 543 +K E+ + + H+N++R++G G + L+ EY+ G+L +L+G + T Sbjct: 48 KKNAEREITHLSEIDHENVIRVIGRASNGKKDYLLMEYLEEGSLHNYLYG--DDKWEYTV 105 Query: 544 EARIKILLGTAKALAYLH 597 E ++ L AKALAYLH Sbjct: 106 EQAVRWALQCAKALAYLH 123
>NTRK3_HUMAN (Q16288) NT-3 growth factor receptor precursor (EC 2.7.10.1)| (Neurotrophic tyrosine kinase receptor type 3) (TrkC tyrosine kinase) (GP145-TrkC) (Trk-C) Length = 839 Score = 48.9 bits (115), Expect = 1e-05 Identities = 24/65 (36%), Positives = 43/65 (66%), Gaps = 2/65 (3%) Frame = +1 Query: 325 VAVKKLLNNLGQAEKEFRVEVEAIGHVRHKNLVRLLGYCVEGTQRILVYEYVNNGNLEQW 504 VAVK L + A K+F+ E E + +++H+++V+ G C +G I+V+EY+ +G+L ++ Sbjct: 569 VAVKALKDPTLAARKDFQREAELLTNLQHEHIVKFYGVCGDGDPLIMVFEYMKHGDLNKF 628 Query: 505 L--HG 513 L HG Sbjct: 629 LRAHG 633
>NTRK3_SAIBB (Q5IS82) NT-3 growth factor receptor precursor (EC 2.7.10.1)| (Neurotrophic tyrosine kinase receptor type 3) Length = 825 Score = 48.9 bits (115), Expect = 1e-05 Identities = 24/65 (36%), Positives = 43/65 (66%), Gaps = 2/65 (3%) Frame = +1 Query: 325 VAVKKLLNNLGQAEKEFRVEVEAIGHVRHKNLVRLLGYCVEGTQRILVYEYVNNGNLEQW 504 VAVK L + A K+F+ E E + +++H+++V+ G C +G I+V+EY+ +G+L ++ Sbjct: 569 VAVKALKDPTLAARKDFQREAELLTNLQHEHIVKFYGVCGDGDPLIMVFEYMKHGDLNKF 628 Query: 505 L--HG 513 L HG Sbjct: 629 LRAHG 633
>NTRK3_PIG (P24786) NT-3 growth factor receptor precursor (EC 2.7.10.1)| (Neurotrophic tyrosine kinase receptor type 3) (TrkC tyrosine kinase) (GP145-TrkC) (Trk-C) Length = 825 Score = 48.9 bits (115), Expect = 1e-05 Identities = 24/65 (36%), Positives = 43/65 (66%), Gaps = 2/65 (3%) Frame = +1 Query: 325 VAVKKLLNNLGQAEKEFRVEVEAIGHVRHKNLVRLLGYCVEGTQRILVYEYVNNGNLEQW 504 VAVK L + A K+F+ E E + +++H+++V+ G C +G I+V+EY+ +G+L ++ Sbjct: 569 VAVKALKDPTLAARKDFQREAELLTNLQHEHIVKFYGVCGDGDPLIMVFEYMKHGDLNKF 628 Query: 505 L--HG 513 L HG Sbjct: 629 LRAHG 633
>NTRK3_PANTR (Q5IS37) NT-3 growth factor receptor precursor (EC 2.7.10.1)| (Neurotrophic tyrosine kinase receptor type 3) Length = 825 Score = 48.9 bits (115), Expect = 1e-05 Identities = 24/65 (36%), Positives = 43/65 (66%), Gaps = 2/65 (3%) Frame = +1 Query: 325 VAVKKLLNNLGQAEKEFRVEVEAIGHVRHKNLVRLLGYCVEGTQRILVYEYVNNGNLEQW 504 VAVK L + A K+F+ E E + +++H+++V+ G C +G I+V+EY+ +G+L ++ Sbjct: 569 VAVKALKDPTLAARKDFQREAELLTNLQHEHIVKFYGVCGDGDPLIMVFEYMKHGDLNKF 628 Query: 505 L--HG 513 L HG Sbjct: 629 LRAHG 633
>NTRK3_MACFA (Q5IFJ9) NT-3 growth factor receptor precursor (EC 2.7.10.1)| (Neurotrophic tyrosine kinase receptor type 3) Length = 825 Score = 48.9 bits (115), Expect = 1e-05 Identities = 24/65 (36%), Positives = 43/65 (66%), Gaps = 2/65 (3%) Frame = +1 Query: 325 VAVKKLLNNLGQAEKEFRVEVEAIGHVRHKNLVRLLGYCVEGTQRILVYEYVNNGNLEQW 504 VAVK L + A K+F+ E E + +++H+++V+ G C +G I+V+EY+ +G+L ++ Sbjct: 569 VAVKALKDPTLAARKDFQREAELLTNLQHEHIVKFYGVCGDGDPLIMVFEYMKHGDLNKF 628 Query: 505 L--HG 513 L HG Sbjct: 629 LRAHG 633
>NTRK3_RAT (Q03351) NT-3 growth factor receptor precursor (EC 2.7.10.1)| (Neurotrophic tyrosine kinase receptor type 3) (TrkC tyrosine kinase) (GP145-TrkC) (Trk-C) Length = 864 Score = 48.9 bits (115), Expect = 1e-05 Identities = 24/65 (36%), Positives = 43/65 (66%), Gaps = 2/65 (3%) Frame = +1 Query: 325 VAVKKLLNNLGQAEKEFRVEVEAIGHVRHKNLVRLLGYCVEGTQRILVYEYVNNGNLEQW 504 VAVK L + A K+F+ E E + +++H+++V+ G C +G I+V+EY+ +G+L ++ Sbjct: 569 VAVKALKDPTLAARKDFQREAELLTNLQHEHIVKFYGVCGDGDPLIMVFEYMKHGDLNKF 628 Query: 505 L--HG 513 L HG Sbjct: 629 LRAHG 633
>ITK_HUMAN (Q08881) Tyrosine-protein kinase ITK/TSK (EC 2.7.10.2)| (T-cell-specific kinase) (Tyrosine-protein kinase Lyk) (Kinase EMT) Length = 620 Score = 48.5 bits (114), Expect = 1e-05 Identities = 30/97 (30%), Positives = 49/97 (50%) Frame = +1 Query: 313 NGTPVAVKKLLNNLGQAEKEFRVEVEAIGHVRHKNLVRLLGYCVEGTQRILVYEYVNNGN 492 N VA+K + +E++F E E + + H LV+L G C+E LV+E++ +G Sbjct: 384 NKDKVAIKTIREG-AMSEEDFIEEAEVMMKLSHPKLVQLYGVCLEQAPICLVFEFMEHGC 442 Query: 493 LEQWLHGAMSHRGSLTWEARIKILLGTAKALAYLHEA 603 L +L + RG E + + L + +AYL EA Sbjct: 443 LSDYLR---TQRGLFAAETLLGMCLDVCEGMAYLEEA 476
>EPHA8_HUMAN (P29322) Ephrin type-A receptor 8 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EEK) (EPH- and ELK-related kinase) (HEK3) Length = 1005 Score = 48.1 bits (113), Expect = 2e-05 Identities = 28/94 (29%), Positives = 47/94 (50%), Gaps = 1/94 (1%) Frame = +1 Query: 322 PVAVKKLLNNLGQAEK-EFRVEVEAIGHVRHKNLVRLLGYCVEGTQRILVYEYVNNGNLE 498 PVA+K L + ++ +F E +G H N++RL G G ++V EY+ NG+L+ Sbjct: 663 PVAIKALKAGYTERQRRDFLSEASIMGQFDHPNIIRLEGVVTRGRLAMIVTEYMENGSLD 722 Query: 499 QWLHGAMSHRGSLTWEARIKILLGTAKALAYLHE 600 +L +H G T + +L G + YL + Sbjct: 723 TFLR---THDGQFTIMQLVGMLRGVGAGMRYLSD 753
>ITK_MOUSE (Q03526) Tyrosine-protein kinase ITK/TSK (EC 2.7.10.2)| (T-cell-specific kinase) (IL-2-inducible T-cell kinase) (Kinase EMT) (Kinase TLK) Length = 625 Score = 48.1 bits (113), Expect = 2e-05 Identities = 30/97 (30%), Positives = 49/97 (50%) Frame = +1 Query: 313 NGTPVAVKKLLNNLGQAEKEFRVEVEAIGHVRHKNLVRLLGYCVEGTQRILVYEYVNNGN 492 N VA+K + +E++F E E + + H LV+L G C+E LV+E++ +G Sbjct: 389 NKDKVAIKTIQEG-AMSEEDFIEEAEVMMKLSHPKLVQLYGVCLEQAPICLVFEFMEHGC 447 Query: 493 LEQWLHGAMSHRGSLTWEARIKILLGTAKALAYLHEA 603 L +L S RG E + + L + +AYL +A Sbjct: 448 LSDYLR---SQRGLFAAETLLGMCLDVCEGMAYLEKA 481
>EPHA8_MOUSE (O09127) Ephrin type-A receptor 8 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EEK) (EPH- and ELK-related kinase) Length = 1004 Score = 47.8 bits (112), Expect = 3e-05 Identities = 28/94 (29%), Positives = 47/94 (50%), Gaps = 1/94 (1%) Frame = +1 Query: 322 PVAVKKLLNNLGQAEKE-FRVEVEAIGHVRHKNLVRLLGYCVEGTQRILVYEYVNNGNLE 498 PVA+K L + +++ F E +G H N++RL G G ++V EY+ NG+L+ Sbjct: 662 PVAIKALKAGYTERQRQDFLSEAAIMGQFDHPNIIRLEGVVTRGRLAMIVTEYMENGSLD 721 Query: 499 QWLHGAMSHRGSLTWEARIKILLGTAKALAYLHE 600 +L +H G T + +L G + YL + Sbjct: 722 AFLR---THDGQFTIVQLVGMLRGVGAGMRYLSD 752
>LIMK2_CHICK (P53666) LIM domain kinase 2 (EC 2.7.11.1) (LIMK-2)| Length = 642 Score = 47.8 bits (112), Expect = 3e-05 Identities = 24/94 (25%), Positives = 47/94 (50%) Frame = +1 Query: 316 GTPVAVKKLLNNLGQAEKEFRVEVEAIGHVRHKNLVRLLGYCVEGTQRILVYEYVNNGNL 495 G + +K+L+ + +K F EV+ + + H N+++ +G + + L+ EY+ G L Sbjct: 354 GKVMVMKELIRCDEETQKTFLTEVKVMRSLDHPNVLKFIGVLYKDKKLNLLTEYIEGGTL 413 Query: 496 EQWLHGAMSHRGSLTWEARIKILLGTAKALAYLH 597 + +L A W+ ++ G A +AYLH Sbjct: 414 KDFLRNA----DPFPWQQKVSFAKGIASGMAYLH 443
>CTR1_ARATH (Q05609) Serine/threonine-protein kinase CTR1 (EC 2.7.11.1)| Length = 821 Score = 47.4 bits (111), Expect = 3e-05 Identities = 32/97 (32%), Positives = 50/97 (51%), Gaps = 2/97 (2%) Frame = +1 Query: 313 NGTPVAVKKLLNNLGQAEK--EFRVEVEAIGHVRHKNLVRLLGYCVEGTQRILVYEYVNN 486 +G+ VAVK L+ AE+ EF EV + +RH N+V +G + +V EY++ Sbjct: 571 HGSDVAVKILMEQDFHAERVNEFLREVAIMKRLRHPNIVLFMGAVTQPPNLSIVTEYLSR 630 Query: 487 GNLEQWLHGAMSHRGSLTWEARIKILLGTAKALAYLH 597 G+L + LH + R L R+ + AK + YLH Sbjct: 631 GSLYRLLHKS-GAREQLDERRRLSMAYDVAKGMNYLH 666
>LIMK2_RAT (P53670) LIM domain kinase 2 (EC 2.7.11.1) (LIMK-2)| Length = 638 Score = 47.0 bits (110), Expect = 4e-05 Identities = 23/94 (24%), Positives = 47/94 (50%) Frame = +1 Query: 316 GTPVAVKKLLNNLGQAEKEFRVEVEAIGHVRHKNLVRLLGYCVEGTQRILVYEYVNNGNL 495 G + +K+L+ + +K F EV+ + + H N+++ +G + + L+ EY+ G L Sbjct: 354 GKVMVMKELIRCDEETQKTFLTEVKVMRSLDHPNVLKFIGVLYKDKKLNLLTEYIEGGTL 413 Query: 496 EQWLHGAMSHRGSLTWEARIKILLGTAKALAYLH 597 + +L W+ +++ G A +AYLH Sbjct: 414 KDFLRNV----DPFPWQQKVRFAKGIASGMAYLH 443
>EPHA8_RAT (P29321) Ephrin type-A receptor 8 (EC 2.7.10.1) (Tyrosine-protein| kinase receptor EEK) (EPH- and ELK-related kinase) (Fragment) Length = 372 Score = 47.0 bits (110), Expect = 4e-05 Identities = 28/94 (29%), Positives = 47/94 (50%), Gaps = 1/94 (1%) Frame = +1 Query: 322 PVAVKKLLNNLGQAEKE-FRVEVEAIGHVRHKNLVRLLGYCVEGTQRILVYEYVNNGNLE 498 PVA+K L + +++ F E +G H N++RL G G ++V EY+ NG+L+ Sbjct: 30 PVAIKALKAGYTERQRQDFLREAAIMGQFDHPNIIRLEGVVTRGRLAMIVTEYMENGSLD 89 Query: 499 QWLHGAMSHRGSLTWEARIKILLGTAKALAYLHE 600 +L +H G T + +L G + YL + Sbjct: 90 AFLR---THDGQFTILQLVGMLKGVGAGMRYLSD 120
>LIMK2_HUMAN (P53671) LIM domain kinase 2 (EC 2.7.11.1) (LIMK-2)| Length = 638 Score = 46.6 bits (109), Expect = 6e-05 Identities = 23/94 (24%), Positives = 47/94 (50%) Frame = +1 Query: 316 GTPVAVKKLLNNLGQAEKEFRVEVEAIGHVRHKNLVRLLGYCVEGTQRILVYEYVNNGNL 495 G + +K+L+ + +K F EV+ + + H N+++ +G + + L+ EY+ G L Sbjct: 354 GKVMVMKELIRCDEETQKTFLTEVKVMRSLDHPNVLKFIGVLYKDKKLNLLTEYIEGGTL 413 Query: 496 EQWLHGAMSHRGSLTWEARIKILLGTAKALAYLH 597 + +L W+ +++ G A +AYLH Sbjct: 414 KDFLRS----MDPFPWQQKVRFAKGIASGMAYLH 443
>ROR1_DROME (Q24488) Tyrosine-protein kinase transmembrane receptor Ror| precursor (EC 2.7.10.1) (dRor) Length = 685 Score = 46.2 bits (108), Expect = 7e-05 Identities = 27/92 (29%), Positives = 53/92 (57%), Gaps = 2/92 (2%) Frame = +1 Query: 325 VAVKKLLNNLG-QAEKEFRVEVEAIGHVRHKNLVRLLGYCVEGTQRILVYEYVNNGNLEQ 501 VA+K L N + +++F+ E+E I ++H+N+V +LG + +++EY+ NG+L + Sbjct: 439 VAIKALKENASVKTQQDFKREIELISDLKHQNIVCILGVVLNKEPYCMLFEYMANGDLHE 498 Query: 502 WLHGAMSHRG-SLTWEARIKILLGTAKALAYL 594 +L G SL+ ++I L ++ + YL Sbjct: 499 FLISNSPTEGKSLSQLEFLQIALQISEGMQYL 530
>ARK1_SCHPO (O59790) Serine/threonine-protein kinase ark1 (EC 2.7.11.1)| (Aurora-related kinase 1) Length = 355 Score = 46.2 bits (108), Expect = 7e-05 Identities = 27/79 (34%), Positives = 42/79 (53%) Frame = +1 Query: 364 EKEFRVEVEAIGHVRHKNLVRLLGYCVEGTQRILVYEYVNNGNLEQWLHGAMSHRGSLTW 543 EK+ R E+E ++RHKN++RL G+ + + L+ E+ G L Q L A + Sbjct: 131 EKQVRREIEIQSNLRHKNILRLYGHFHDEKRIYLILEFAGRGELYQHLRRAK----RFSE 186 Query: 544 EARIKILLGTAKALAYLHE 600 E K + A AL+YLH+ Sbjct: 187 EVASKYIFQMANALSYLHK 205
>LIMK2_MOUSE (O54785) LIM domain kinase 2 (EC 2.7.11.1) (LIMK-2)| Length = 638 Score = 45.8 bits (107), Expect = 1e-04 Identities = 22/94 (23%), Positives = 47/94 (50%) Frame = +1 Query: 316 GTPVAVKKLLNNLGQAEKEFRVEVEAIGHVRHKNLVRLLGYCVEGTQRILVYEYVNNGNL 495 G + +K+L+ + +K F EV+ + + H N+++ +G + + L+ EY+ G L Sbjct: 354 GKVMVMKELIRCDEETQKTFLTEVKVMRSLDHPNVLKFIGVLYKDKKLNLLTEYIEGGTL 413 Query: 496 EQWLHGAMSHRGSLTWEARIKILLGTAKALAYLH 597 + +L W+ +++ G + +AYLH Sbjct: 414 KDFLRSV----DPFPWQQKVRFAKGISSGMAYLH 443
>GUC2C_HUMAN (P25092) Heat-stable enterotoxin receptor precursor (GC-C)| (Intestinal guanylate cyclase) (EC 4.6.1.2) (STA receptor) (hSTAR) Length = 1073 Score = 45.4 bits (106), Expect = 1e-04 Identities = 26/95 (27%), Positives = 48/95 (50%), Gaps = 2/95 (2%) Frame = +1 Query: 325 VAVKKLLNNLGQAEKEFRVEVEAIGHVRHKNLVRLLGYCVEGTQRILVYEYVNNGNLEQW 504 V +K L +N G ++ ++E+ + + + NL + G T V EY G+L + Sbjct: 513 VILKDLKHNDGNFTEKQKIELNKLLQIDYYNLTKFYGTVKLDTMIFGVIEYCERGSLREV 572 Query: 505 LHGAMSHRGS--LTWEARIKILLGTAKALAYLHEA 603 L+ +S+ + WE +I +L AK ++YLH + Sbjct: 573 LNDTISYPDGTFMDWEFKISVLYDIAKGMSYLHSS 607
>IPL1_YARLI (Q6C3J2) Spindle assembly checkpoint kinase (EC 2.7.11.1) (Aurora| kinase) Length = 371 Score = 45.1 bits (105), Expect = 2e-04 Identities = 27/81 (33%), Positives = 43/81 (53%) Frame = +1 Query: 355 GQAEKEFRVEVEAIGHVRHKNLVRLLGYCVEGTQRILVYEYVNNGNLEQWLHGAMSHRGS 534 G EK+FR EVE ++RH N++RL G+ + + L+ EYV +G L + L ++ Sbjct: 138 GNVEKQFRREVEIQSNLRHTNVLRLFGHFHDKDRVYLILEYVVHGELYKLLR----NQKR 193 Query: 535 LTWEARIKILLGTAKALAYLH 597 T + ++AL YLH Sbjct: 194 FTESTASSYIYQMSEALLYLH 214
>IPL1_ASHGO (Q755C4) Spindle assembly checkpoint kinase (EC 2.7.11.1) (Aurora| kinase) Length = 367 Score = 44.3 bits (103), Expect = 3e-04 Identities = 30/79 (37%), Positives = 42/79 (53%) Frame = +1 Query: 364 EKEFRVEVEAIGHVRHKNLVRLLGYCVEGTQRILVYEYVNNGNLEQWLHGAMSHRGSLTW 543 EK+FR EVE +RH NL +L GY + + L+ EY+ NG L + L G SH + Sbjct: 151 EKQFRREVEIQSSLRHPNLTQLYGYFHDEKRVYLLMEYLVNGELYKHLKG-RSHFNDVVA 209 Query: 544 EARIKILLGTAKALAYLHE 600 + + A AL Y+HE Sbjct: 210 SYYVYQM---ADALDYMHE 225
>EPHAA_HUMAN (Q5JZY3) Ephrin type-A receptor 10 precursor (EC 2.7.10.1)| Length = 1008 Score = 44.3 bits (103), Expect = 3e-04 Identities = 29/93 (31%), Positives = 48/93 (51%), Gaps = 1/93 (1%) Frame = +1 Query: 325 VAVKKLLNNLGQAEK-EFRVEVEAIGHVRHKNLVRLLGYCVEGTQRILVYEYVNNGNLEQ 501 VAV L ++ +++ F E +G H ++VRL G G+ ++V EY+++G L+ Sbjct: 674 VAVHMLRDSASDSQRLGFLAEALTLGQFDHSHIVRLEGVVTRGSTLMIVTEYMSHGALDG 733 Query: 502 WLHGAMSHRGSLTWEARIKILLGTAKALAYLHE 600 +L H G L + +L G A A+ YL E Sbjct: 734 FLR---RHEGQLVAGQLMGLLPGLASAMKYLSE 763
>RTK2_GEOCY (P42159) Class II receptor tyrosine kinase (EC 2.7.10.1) (GCTK)| Length = 605 Score = 43.9 bits (102), Expect = 4e-04 Identities = 21/62 (33%), Positives = 38/62 (61%), Gaps = 1/62 (1%) Frame = +1 Query: 325 VAVKKLLNNLGQAEKE-FRVEVEAIGHVRHKNLVRLLGYCVEGTQRILVYEYVNNGNLEQ 501 VAVKKL ++ + ++ F E++ + ++H ++V+LL C +V EY+ NG+L Q Sbjct: 390 VAVKKLKPDVSEEVRQSFDKEIKFVSQLQHDSIVQLLAVCTHSKHPFIVMEYMENGDLNQ 449 Query: 502 WL 507 +L Sbjct: 450 FL 451
>EPHA7_CHICK (O42422) Ephrin type-A receptor 7 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor CEPHA7) (Tyrosine-protein kinase receptor CEK11) Length = 993 Score = 43.9 bits (102), Expect = 4e-04 Identities = 31/93 (33%), Positives = 44/93 (47%), Gaps = 3/93 (3%) Frame = +1 Query: 325 VAVKKLLNNLGQAEKE---FRVEVEAIGHVRHKNLVRLLGYCVEGTQRILVYEYVNNGNL 495 VA+K L +G EK+ F E +G H N+V L G G ++V EY+ NG L Sbjct: 657 VAIKTL--KVGYTEKQRRDFLCEASIMGQFDHPNVVHLEGVVTRGKPVMIVIEYMENGAL 714 Query: 496 EQWLHGAMSHRGSLTWEARIKILLGTAKALAYL 594 + +L H G T + +L G A + YL Sbjct: 715 DAFLR---KHDGQFTVIQLVGMLRGIAAGMRYL 744
>HT1_ARATH (Q2MHE4) Serine/threonine-protein kinase HT1 (EC 2.7.11.1) (High| leaf temperature protein 1) Length = 390 Score = 43.9 bits (102), Expect = 4e-04 Identities = 21/78 (26%), Positives = 44/78 (56%) Frame = +1 Query: 364 EKEFRVEVEAIGHVRHKNLVRLLGYCVEGTQRILVYEYVNNGNLEQWLHGAMSHRGSLTW 543 E++F+ EV + + H N+V+ + C + ++ EY++ GNL +L+ + SL+ Sbjct: 129 EQQFKSEVALLSRLFHPNIVQFIAACKKPPVYCIITEYMSQGNLRMYLNKKEPY--SLSI 186 Query: 544 EARIKILLGTAKALAYLH 597 E +++ L ++ + YLH Sbjct: 187 ETVLRLALDISRGMEYLH 204
>EPHA3_MOUSE (P29319) Ephrin type-A receptor 3 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor ETK1) (MEK4) Length = 983 Score = 43.9 bits (102), Expect = 4e-04 Identities = 29/95 (30%), Positives = 46/95 (48%), Gaps = 3/95 (3%) Frame = +1 Query: 325 VAVKKLLNNLGQAEKE---FRVEVEAIGHVRHKNLVRLLGYCVEGTQRILVYEYVNNGNL 495 VA+K L +G EK+ F E +G H N++RL G + ++V EY+ NG+L Sbjct: 650 VAIKTL--KVGYTEKQRRDFLGEASIMGQFDHPNIIRLEGVVTKSKPEMIVTEYMENGSL 707 Query: 496 EQWLHGAMSHRGSLTWEARIKILLGTAKALAYLHE 600 + +L H T + +L G A + YL + Sbjct: 708 DSFLR---KHDAQFTVIQLVGMLRGIASGMKYLSD 739
>GUC2C_PIG (P55204) Heat-stable enterotoxin receptor precursor (GC-C)| (Intestinal guanylate cyclase) (EC 4.6.1.2) (STA receptor) Length = 1073 Score = 43.9 bits (102), Expect = 4e-04 Identities = 25/95 (26%), Positives = 48/95 (50%), Gaps = 2/95 (2%) Frame = +1 Query: 325 VAVKKLLNNLGQAEKEFRVEVEAIGHVRHKNLVRLLGYCVEGTQRILVYEYVNNGNLEQW 504 V +K L +N G ++ ++E+ + + + NL + G + V EY G+L + Sbjct: 513 VILKDLKHNDGNFTEKQKIELNKLLQIDYYNLTKFYGTVKLDSMIFGVIEYCERGSLREV 572 Query: 505 LHGAMSHRGS--LTWEARIKILLGTAKALAYLHEA 603 L+ +S+ + WE +I +L AK ++YLH + Sbjct: 573 LNDTISYPDGTFMDWEFKISVLYDIAKGMSYLHSS 607
>ICL1_KLULA (Q6CWQ4) Spindle assembly checkpoint kinase (EC 2.7.11.1) (Aurora| kinase) Length = 361 Score = 43.5 bits (101), Expect = 5e-04 Identities = 27/78 (34%), Positives = 40/78 (51%) Frame = +1 Query: 364 EKEFRVEVEAIGHVRHKNLVRLLGYCVEGTQRILVYEYVNNGNLEQWLHGAMSHRGSLTW 543 +K+FR EVE G +HKNL +L G+ + + L+ EYV G L ++L + G L Sbjct: 142 QKQFRREVEIQGSFKHKNLTQLYGFFYDEKRVYLLMEYVYYGELYKFL----KNNGPLNE 197 Query: 544 EARIKILLGTAKALAYLH 597 + A AL Y+H Sbjct: 198 TLASYFVYQMANALDYMH 215
>EPHA3_BRARE (O13146) Ephrin type-A receptor 3 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor ZEK1) (EPH-like kinase 1) Length = 981 Score = 43.1 bits (100), Expect = 6e-04 Identities = 28/93 (30%), Positives = 45/93 (48%), Gaps = 1/93 (1%) Frame = +1 Query: 325 VAVKKLLNNLGQAEK-EFRVEVEAIGHVRHKNLVRLLGYCVEGTQRILVYEYVNNGNLEQ 501 VA+K L + ++ +F E +G H N++RL G ++V EY+ NG+L+ Sbjct: 655 VAIKSLKAGYSEHQRRDFLSEASIMGQFDHPNIIRLEGVVTRCKPVMIVTEYMENGSLDT 714 Query: 502 WLHGAMSHRGSLTWEARIKILLGTAKALAYLHE 600 +L H G T + +L G A + YL E Sbjct: 715 FL---KKHDGQFTVIQLLGMLRGIAAGMQYLSE 744
>TYK2_MOUSE (Q9R117) Non-receptor tyrosine-protein kinase TYK2 (EC 2.7.10.2)| Length = 1180 Score = 43.1 bits (100), Expect = 6e-04 Identities = 23/69 (33%), Positives = 37/69 (53%) Frame = +1 Query: 394 IGHVRHKNLVRLLGYCVEGTQRILVYEYVNNGNLEQWLHGAMSHRGSLTWEARIKILLGT 573 + V H +L L G CV G++ I+V E+V +G L+ WL RG + ++ + Sbjct: 655 MSQVSHMHLAFLHGVCVRGSENIIVTEFVEHGPLDVWLR---RQRGQVPMTWKMVVAQQL 711 Query: 574 AKALAYLHE 600 A AL+YL + Sbjct: 712 ASALSYLED 720
>ABL_DROME (P00522) Tyrosine-protein kinase Abl (EC 2.7.10.2) (Abelson| protein) (D-ash) Length = 1620 Score = 42.7 bits (99), Expect = 8e-04 Identities = 29/93 (31%), Positives = 48/93 (51%) Frame = +1 Query: 316 GTPVAVKKLLNNLGQAEKEFRVEVEAIGHVRHKNLVRLLGYCVEGTQRILVYEYVNNGNL 495 G VAVK L + A K+F E + ++H NLV+L+G C ++ E++++GNL Sbjct: 394 GNTVAVKTLKEDT-MALKDFLEEAAIMKEMKHPNLVQLIGVCTREPPFYIITEFMSHGNL 452 Query: 496 EQWLHGAMSHRGSLTWEARIKILLGTAKALAYL 594 +L A R +L A + + A ++YL Sbjct: 453 LDFLRSA--GRETLDAVALLYMATQIASGMSYL 483
>SPK1_DUGTI (P42687) Tyrosine-protein kinase SPK-1 (EC 2.7.10.2)| Length = 497 Score = 42.7 bits (99), Expect = 8e-04 Identities = 26/92 (28%), Positives = 51/92 (55%), Gaps = 2/92 (2%) Frame = +1 Query: 325 VAVKKLLNNLGQAEKEFRVEVEAIGHVRHKNLVRLLGYCVE--GTQRILVYEYVNNGNLE 498 VA K L ++ + EK F +E + + +RH+ +V LLG C E +++ EY+ NG+L+ Sbjct: 245 VAAKMLQSSKAEREK-FVLEAKIMHKLRHRKIVELLGVCTEPQDMPMLIIVEYMKNGSLK 303 Query: 499 QWLHGAMSHRGSLTWEARIKILLGTAKALAYL 594 ++L + +L + ++ ++ +AYL Sbjct: 304 EYLKTPDGKKTNL--NQMVHMMAEISEGMAYL 333
>FGFR4_RAT (Q498D6) Fibroblast growth factor receptor 4 precursor (EC| 2.7.10.1) (FGFR-4) Length = 800 Score = 42.7 bits (99), Expect = 8e-04 Identities = 30/104 (28%), Positives = 48/104 (46%), Gaps = 14/104 (13%) Frame = +1 Query: 325 VAVKKLLNNLGQAE-KEFRVEVEAIGHV-RHKNLVRLLGYCVEGTQRILVYEYVNNGNLE 498 VAVK L +N + + E+E + + RHKN++ LLG C + ++ EY GNL Sbjct: 498 VAVKMLKDNASDKDLADLISEMEMMKLIGRHKNIINLLGVCTQEGPLYVIVEYAAKGNLR 557 Query: 499 QWLH------------GAMSHRGSLTWEARIKILLGTAKALAYL 594 ++L G S G L++ A + A+ + YL Sbjct: 558 EFLRARRPPGPDLSPDGPRSSEGPLSFPALVSCAYQVARGMQYL 601
>EPHA3_HUMAN (P29320) Ephrin type-A receptor 3 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor ETK1) (HEK) (HEK4) Length = 983 Score = 42.7 bits (99), Expect = 8e-04 Identities = 29/95 (30%), Positives = 46/95 (48%), Gaps = 3/95 (3%) Frame = +1 Query: 325 VAVKKLLNNLGQAEKE---FRVEVEAIGHVRHKNLVRLLGYCVEGTQRILVYEYVNNGNL 495 VA+K L +G EK+ F E +G H N++RL G + ++V EY+ NG+L Sbjct: 650 VAIKTL--KVGYTEKQRRDFLGEASIMGQFDHPNIIRLEGVVTKSKPVMIVTEYMENGSL 707 Query: 496 EQWLHGAMSHRGSLTWEARIKILLGTAKALAYLHE 600 + +L H T + +L G A + YL + Sbjct: 708 DSFLR---KHDAQFTVIQLVGMLRGIASGMKYLSD 739
>AURKC_MOUSE (O88445) Serine/threonine-protein kinase 13 (EC 2.7.11.1)| (Aurora/Ipl1/Eg2 protein 1) (Aurora-C) Length = 282 Score = 42.7 bits (99), Expect = 8e-04 Identities = 24/79 (30%), Positives = 38/79 (48%) Frame = +1 Query: 364 EKEFRVEVEAIGHVRHKNLVRLLGYCVEGTQRILVYEYVNNGNLEQWLHGAMSHRGSLTW 543 E + R EVE H++H+N++RL Y + T+ L+ EY G L+ + L Sbjct: 58 EHQLRREVEIQAHLQHRNILRLYNYFYDDTRIYLILEYAPGGE----LYKELQRHQKLDQ 113 Query: 544 EARIKILLGTAKALAYLHE 600 + I+ + AL Y HE Sbjct: 114 QRTATIIQELSDALTYCHE 132
>LTK_MOUSE (P08923) Leukocyte tyrosine kinase receptor precursor (EC 2.7.10.1)| Length = 888 Score = 42.7 bits (99), Expect = 8e-04 Identities = 27/97 (27%), Positives = 48/97 (49%), Gaps = 4/97 (4%) Frame = +1 Query: 322 PVAVKKLLNNLG-QAEKEFRVEVEAIGHVRHKNLVRLLGYCVEGTQRILVYEYVNNGNLE 498 PVA+K L Q E +F +E I H+N+VR +G R+++ E ++ G+++ Sbjct: 536 PVAIKTLPELCSHQDELDFLMEALIISKFSHQNIVRCVGLSFRSAPRLILLELMSGGDMK 595 Query: 499 QWLHGAMSHRGS---LTWEARIKILLGTAKALAYLHE 600 +L + H G LT + +++ A+ YL E Sbjct: 596 SFLRHSRPHPGQLAPLTMQDLLQLAQDIAQGCHYLEE 632
>EPHA3_RAT (O08680) Ephrin type-A receptor 3 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor REK4) (TYRO-4) Length = 984 Score = 42.7 bits (99), Expect = 8e-04 Identities = 29/95 (30%), Positives = 46/95 (48%), Gaps = 3/95 (3%) Frame = +1 Query: 325 VAVKKLLNNLGQAEKE---FRVEVEAIGHVRHKNLVRLLGYCVEGTQRILVYEYVNNGNL 495 VA+K L +G EK+ F E +G H N++RL G + ++V EY+ NG+L Sbjct: 651 VAIKTL--KVGYTEKQRRDFLGEASIMGQFDHPNIIRLEGVVTKSKPVMIVTEYMENGSL 708 Query: 496 EQWLHGAMSHRGSLTWEARIKILLGTAKALAYLHE 600 + +L H T + +L G A + YL + Sbjct: 709 DSFLR---KHDAQFTVIQLVGMLRGIASGMKYLSD 740
>JAK1_MOUSE (P52332) Tyrosine-protein kinase JAK1 (EC 2.7.10.2) (Janus kinase| 1) (JAK-1) Length = 1153 Score = 42.4 bits (98), Expect = 0.001 Identities = 23/66 (34%), Positives = 36/66 (54%) Frame = +1 Query: 403 VRHKNLVRLLGYCVEGTQRILVYEYVNNGNLEQWLHGAMSHRGSLTWEARIKILLGTAKA 582 V HK++V L G CV + I+V E+V G L+ ++H +LT + K+ A A Sbjct: 644 VSHKHIVYLYGVCVRDVENIMVEEFVEGGPLDLFMH---RKSDALTTPWKFKVAKQLASA 700 Query: 583 LAYLHE 600 L+YL + Sbjct: 701 LSYLED 706 Score = 38.9 bits (89), Expect = 0.012 Identities = 25/96 (26%), Positives = 51/96 (53%), Gaps = 3/96 (3%) Frame = +1 Query: 316 GTPVAVKKLLNNLGQAE-KEFRVEVEAIGHVRHKNLVRLLGYCVE--GTQRILVYEYVNN 486 G VAVK L G + + E+E + ++ H+N+V+ G C+E G L+ E++ + Sbjct: 901 GEQVAVKSLKPESGGNHIADLKKEIEILRNLYHENIVKYKGICMEDGGNGIKLIMEFLPS 960 Query: 487 GNLEQWLHGAMSHRGSLTWEARIKILLGTAKALAYL 594 G+L+++L ++ + + ++K + K + YL Sbjct: 961 GSLKEYL---PKNKNKINLKQQLKYAIQICKGMDYL 993
>DDR1_PANTR (Q7YR43) Epithelial discoidin domain-containing receptor 1| precursor (EC 2.7.10.1) (Epithelial discoidin domain receptor 1) (Tyrosine kinase DDR) (Discoidin receptor tyrosine kinase) (CD167a antigen) Length = 909 Score = 42.4 bits (98), Expect = 0.001 Identities = 22/62 (35%), Positives = 38/62 (61%), Gaps = 1/62 (1%) Frame = +1 Query: 325 VAVKKLLNNLGQ-AEKEFRVEVEAIGHVRHKNLVRLLGYCVEGTQRILVYEYVNNGNLEQ 501 VAVK L + + A +F EV+ + ++ N++RLLG CV+ ++ +Y+ NG+L Q Sbjct: 648 VAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQ 707 Query: 502 WL 507 +L Sbjct: 708 FL 709
>SRC42_DROME (Q9V9J3) Tyrosine-protein kinase Src42A (EC 2.7.10.2) (Dsrc41)| Length = 517 Score = 42.4 bits (98), Expect = 0.001 Identities = 26/94 (27%), Positives = 44/94 (46%) Frame = +1 Query: 313 NGTPVAVKKLLNNLGQAEKEFRVEVEAIGHVRHKNLVRLLGYCVEGTQRILVYEYVNNGN 492 N TPVA+K L + K+F E + + +RH L++L C ++ E + +G+ Sbjct: 269 NTTPVAIKTLKSGT-MDPKDFLAEAQIMKKLRHTKLIQLYAVCTVEEPIYIITELMKHGS 327 Query: 493 LEQWLHGAMSHRGSLTWEARIKILLGTAKALAYL 594 L ++L SL + I + A +AYL Sbjct: 328 LLEYLQAIAGKGRSLKMQTLIDMAAQIAAGMAYL 361
>ERBB4_RAT (Q62956) Receptor tyrosine-protein kinase erbB-4 precursor (EC| 2.7.10.1) Length = 1308 Score = 42.4 bits (98), Expect = 0.001 Identities = 31/94 (32%), Positives = 50/94 (53%), Gaps = 1/94 (1%) Frame = +1 Query: 322 PVAVKKLLNNLG-QAEKEFRVEVEAIGHVRHKNLVRLLGYCVEGTQRILVYEYVNNGNLE 498 PVA+K L G +A EF E + V H +LVRLLG C+ T + LV + + +G L Sbjct: 747 PVAIKILNETTGPKANVEFMDEALIMASVDHPHLVRLLGVCLSPTIQ-LVTQLMPHGCLL 805 Query: 499 QWLHGAMSHRGSLTWEARIKILLGTAKALAYLHE 600 +++H H+ ++ + + + AK + YL E Sbjct: 806 EYVH---EHKDNIGSQLLLNWCVQIAKGMMYLEE 836
>EPHA7_RAT (P54759) Ephrin type-A receptor 7 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EHK-3) (EPH homology kinase 3) Length = 998 Score = 42.4 bits (98), Expect = 0.001 Identities = 30/93 (32%), Positives = 44/93 (47%), Gaps = 3/93 (3%) Frame = +1 Query: 325 VAVKKLLNNLGQAEKE---FRVEVEAIGHVRHKNLVRLLGYCVEGTQRILVYEYVNNGNL 495 VA+K L +G EK+ F E +G H N+V L G G ++V E++ NG L Sbjct: 662 VAIKTL--KVGYTEKQRRDFLCEASIMGQFDHPNVVHLEGVVTRGKPVMIVIEFMENGAL 719 Query: 496 EQWLHGAMSHRGSLTWEARIKILLGTAKALAYL 594 + +L H G T + +L G A + YL Sbjct: 720 DAFLR---KHDGQFTVIQLVGMLRGIAAGMRYL 749
>EPHA7_MOUSE (Q61772) Ephrin type-A receptor 7 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EHK-3) (EPH homology kinase 3) (Embryonic brain kinase) (EBK) (Developmental kinase 1) (MDK-1) Length = 998 Score = 42.4 bits (98), Expect = 0.001 Identities = 30/93 (32%), Positives = 44/93 (47%), Gaps = 3/93 (3%) Frame = +1 Query: 325 VAVKKLLNNLGQAEKE---FRVEVEAIGHVRHKNLVRLLGYCVEGTQRILVYEYVNNGNL 495 VA+K L +G EK+ F E +G H N+V L G G ++V E++ NG L Sbjct: 662 VAIKTL--KVGYTEKQRRDFLCEASIMGQFDHPNVVHLEGVVTRGKPVMIVIEFMENGAL 719 Query: 496 EQWLHGAMSHRGSLTWEARIKILLGTAKALAYL 594 + +L H G T + +L G A + YL Sbjct: 720 DAFLR---KHDGQFTVIQLVGMLRGIAAGMRYL 749
>EPHA7_HUMAN (Q15375) Ephrin type-A receptor 7 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EHK-3) (EPH homology kinase 3) (Receptor protein-tyrosine kinase HEK11) Length = 998 Score = 42.4 bits (98), Expect = 0.001 Identities = 30/93 (32%), Positives = 44/93 (47%), Gaps = 3/93 (3%) Frame = +1 Query: 325 VAVKKLLNNLGQAEKE---FRVEVEAIGHVRHKNLVRLLGYCVEGTQRILVYEYVNNGNL 495 VA+K L +G EK+ F E +G H N+V L G G ++V E++ NG L Sbjct: 662 VAIKTL--KVGYTEKQRRDFLCEASIMGQFDHPNVVHLEGVVTRGKPVMIVIEFMENGAL 719 Query: 496 EQWLHGAMSHRGSLTWEARIKILLGTAKALAYL 594 + +L H G T + +L G A + YL Sbjct: 720 DAFLR---KHDGQFTVIQLVGMLRGIAAGMRYL 749
>DDR1_MOUSE (Q03146) Epithelial discoidin domain-containing receptor 1| precursor (EC 2.7.10.1) (Epithelial discoidin domain receptor 1) (Tyrosine kinase DDR) (Discoidin receptor tyrosine kinase) (Tyrosine-protein kinase CAK) (Cell adhesion kinase) (Protei Length = 911 Score = 42.4 bits (98), Expect = 0.001 Identities = 22/62 (35%), Positives = 38/62 (61%), Gaps = 1/62 (1%) Frame = +1 Query: 325 VAVKKLLNNLGQ-AEKEFRVEVEAIGHVRHKNLVRLLGYCVEGTQRILVYEYVNNGNLEQ 501 VAVK L + + A +F EV+ + ++ N++RLLG CV+ ++ +Y+ NG+L Q Sbjct: 650 VAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQ 709 Query: 502 WL 507 +L Sbjct: 710 FL 711
>EPHA5_CHICK (P54755) Ephrin type-A receptor 5 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor CEK7) Length = 1013 Score = 42.4 bits (98), Expect = 0.001 Identities = 29/96 (30%), Positives = 47/96 (48%), Gaps = 3/96 (3%) Frame = +1 Query: 322 PVAVKKLLNNLGQAEKE---FRVEVEAIGHVRHKNLVRLLGYCVEGTQRILVYEYVNNGN 492 PVA+K L +G EK+ F E +G H N++ L G + ++V EY+ NG+ Sbjct: 679 PVAIKTL--KVGYTEKQRRDFLGEASIMGQFDHPNIIHLEGVVTKSKPVMIVTEYMENGS 736 Query: 493 LEQWLHGAMSHRGSLTWEARIKILLGTAKALAYLHE 600 L+ +L + G T + +L G A + YL + Sbjct: 737 LDTFL---KKNDGQFTVIQLVGMLRGIASGMKYLSD 769
>DDR1_HUMAN (Q08345) Epithelial discoidin domain-containing receptor 1| precursor (EC 2.7.10.1) (Epithelial discoidin domain receptor 1) (Tyrosine kinase DDR) (Discoidin receptor tyrosine kinase) (Tyrosine-protein kinase CAK) (Cell adhesion kinase) (TRK E) Length = 913 Score = 42.4 bits (98), Expect = 0.001 Identities = 22/62 (35%), Positives = 38/62 (61%), Gaps = 1/62 (1%) Frame = +1 Query: 325 VAVKKLLNNLGQ-AEKEFRVEVEAIGHVRHKNLVRLLGYCVEGTQRILVYEYVNNGNLEQ 501 VAVK L + + A +F EV+ + ++ N++RLLG CV+ ++ +Y+ NG+L Q Sbjct: 652 VAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQ 711 Query: 502 WL 507 +L Sbjct: 712 FL 713
>M3K7_DROME (Q9V3Q6) Mitogen-activated protein kinase kinase kinase 7 (EC| 2.7.11.25) (TGF-beta-activated kinase 1) (dTAK1) Length = 678 Score = 42.4 bits (98), Expect = 0.001 Identities = 29/95 (30%), Positives = 46/95 (48%), Gaps = 4/95 (4%) Frame = +1 Query: 325 VAVKKLLNNLGQAEKEFRVEVEAIGHVRHKNLVRLLGYCVEGTQRILVYEYVNNGNLEQW 504 VAVK+ + Q K+ EV+ + V+H N++ L G L+ E+ G+L + Sbjct: 43 VAVKEFFASAEQ--KDIEKEVKQLSRVKHPNIIALHGISSYQQATYLIMEFAEGGSLHNF 100 Query: 505 LHG----AMSHRGSLTWEARIKILLGTAKALAYLH 597 LHG A S +++W + A+ LAYLH Sbjct: 101 LHGKVKPAYSLAHAMSWARQ------CAEGLAYLH 129
>LTK_HUMAN (P29376) Leukocyte tyrosine kinase receptor precursor (EC 2.7.10.1)| (Protein tyrosine kinase 1) Length = 864 Score = 42.4 bits (98), Expect = 0.001 Identities = 23/84 (27%), Positives = 43/84 (51%), Gaps = 3/84 (3%) Frame = +1 Query: 358 QAEKEFRVEVEAIGHVRHKNLVRLLGYCVEGTQRILVYEYVNNGNLEQWLHGAMSHRGS- 534 Q E +F +E I RH+N+VR +G + T R+++ E ++ G+++ +L + H G Sbjct: 553 QDELDFLMEALIISKFRHQNIVRCVGLSLRATPRLILLELMSGGDMKSFLRHSRPHLGQP 612 Query: 535 --LTWEARIKILLGTAKALAYLHE 600 L +++ A+ YL E Sbjct: 613 SPLVMRDLLQLAQDIAQGCHYLEE 636
>M3K7_MOUSE (Q62073) Mitogen-activated protein kinase kinase kinase 7 (EC| 2.7.11.25) (Transforming growth factor-beta-activated kinase 1) (TGF-beta-activated kinase 1) Length = 579 Score = 42.0 bits (97), Expect = 0.001 Identities = 30/96 (31%), Positives = 47/96 (48%), Gaps = 5/96 (5%) Frame = +1 Query: 325 VAVKKLLNNLGQAEKEFRVEVEAIGHVRHKNLVRLLGYCVEGTQRILVYEYVNNGNLEQW 504 VA+K++ + K F VE+ + V H N+V+L G C+ LV EY G+L Sbjct: 60 VAIKQIESE--SERKAFIVELRQLSRVNHPNIVKLYGACLNPV--CLVMEYAEGGSLYNV 115 Query: 505 LHGA-----MSHRGSLTWEARIKILLGTAKALAYLH 597 LHGA + +++W L ++ +AYLH Sbjct: 116 LHGAEPLPYYTAAHAMSW------CLQCSQGVAYLH 145
>JAK2_MOUSE (Q62120) Tyrosine-protein kinase JAK2 (EC 2.7.10.2) (Janus kinase 2)| (JAK-2) Length = 1129 Score = 42.0 bits (97), Expect = 0.001 Identities = 26/95 (27%), Positives = 48/95 (50%), Gaps = 2/95 (2%) Frame = +1 Query: 316 GTPVAVKKLLNNLGQAEKEFRVEVEAIGHVRHKNLVRLLGYCVEGTQR--ILVYEYVNNG 489 G VAVKKL ++ + ++F E+E + ++H N+V+ G C +R L+ EY+ G Sbjct: 876 GEVVAVKKLQHSTEEHLRDFEREIEILKSLQHDNIVKYKGVCYSAGRRNLRLIMEYLPYG 935 Query: 490 NLEQWLHGAMSHRGSLTWEARIKILLGTAKALAYL 594 +L +L H+ + + ++ K + YL Sbjct: 936 SLRDYL---QKHKERIDHKKLLQYTSQICKGMEYL 967 Score = 37.4 bits (85), Expect = 0.034 Identities = 29/97 (29%), Positives = 45/97 (46%) Frame = +1 Query: 319 TPVAVKKLLNNLGQAEKEFRVEVEAIGHVRHKNLVRLLGYCVEGTQRILVYEYVNNGNLE 498 T V +K L + F + + HK+LV G CV G + ILV E+V G+L+ Sbjct: 576 TEVLLKVLDKAHRNYSESFFEAASMMSQLSHKHLVLNYGVCVCGEENILVQEFVKFGSLD 635 Query: 499 QWLHGAMSHRGSLTWEARIKILLGTAKALAYLHEAIE 609 +L + ++ W+ LG AK LA+ +E Sbjct: 636 TYLK-KNKNSINILWK------LGVAKQLAWAMHFLE 665
>FPS_AVISP (P00541) Tyrosine-protein kinase transforming protein Fps (EC| 2.7.10.2) Length = 533 Score = 42.0 bits (97), Expect = 0.001 Identities = 28/95 (29%), Positives = 43/95 (45%), Gaps = 1/95 (1%) Frame = +1 Query: 313 NGTPVAVKKLLNNLG-QAEKEFRVEVEAIGHVRHKNLVRLLGYCVEGTQRILVYEYVNNG 489 + TPVAVK L + + +F E + H N+VRL+G C + +V E V G Sbjct: 294 DNTPVAVKSCRETLPPELKAKFLQEARILKQYNHPNIVRLIGVCTQKQPIYIVMELVQGG 353 Query: 490 NLEQWLHGAMSHRGSLTWEARIKILLGTAKALAYL 594 + +L H L + IK++ A + YL Sbjct: 354 DFLSFLRSKGPH---LKMKELIKMMENAAAGMEYL 385
>M3K7_HUMAN (O43318) Mitogen-activated protein kinase kinase kinase 7 (EC| 2.7.11.25) (Transforming growth factor-beta-activated kinase 1) (TGF-beta-activated kinase 1) Length = 606 Score = 42.0 bits (97), Expect = 0.001 Identities = 30/96 (31%), Positives = 47/96 (48%), Gaps = 5/96 (5%) Frame = +1 Query: 325 VAVKKLLNNLGQAEKEFRVEVEAIGHVRHKNLVRLLGYCVEGTQRILVYEYVNNGNLEQW 504 VA+K++ + K F VE+ + V H N+V+L G C+ LV EY G+L Sbjct: 60 VAIKQIESE--SERKAFIVELRQLSRVNHPNIVKLYGACLNPV--CLVMEYAEGGSLYNV 115 Query: 505 LHGA-----MSHRGSLTWEARIKILLGTAKALAYLH 597 LHGA + +++W L ++ +AYLH Sbjct: 116 LHGAEPLPYYTAAHAMSW------CLQCSQGVAYLH 145
>KYK1_DICDI (P18160) Non-receptor tyrosine kinase spore lysis A (EC 2.7.10.2)| (Tyrosine-protein kinase 1) Length = 1584 Score = 42.0 bits (97), Expect = 0.001 Identities = 30/100 (30%), Positives = 51/100 (51%), Gaps = 7/100 (7%) Frame = +1 Query: 319 TPVAVKKLLNNLGQAEKE---FRVEVEAIGHVRHKNLVRLLGYCVEGTQ--RILVYEYVN 483 T VA+K + + + + F+ EV + +RH N+V+ LG C G + +V E++ Sbjct: 1311 TDVAIKIIYRDQFKTKSSLVMFQNEVGILSKLRHPNVVQFLGACTAGGEDHHCIVTEWMG 1370 Query: 484 NGNLEQWL--HGAMSHRGSLTWEARIKILLGTAKALAYLH 597 G+L Q+L H + + R+K+ L AK + YLH Sbjct: 1371 GGSLRQFLTDHFNLLEQNP---HIRLKLALDIAKGMNYLH 1407
>JAK2_RAT (Q62689) Tyrosine-protein kinase JAK2 (EC 2.7.10.2) (Janus kinase 2)| (JAK-2) Length = 1132 Score = 42.0 bits (97), Expect = 0.001 Identities = 26/95 (27%), Positives = 48/95 (50%), Gaps = 2/95 (2%) Frame = +1 Query: 316 GTPVAVKKLLNNLGQAEKEFRVEVEAIGHVRHKNLVRLLGYCVEGTQR--ILVYEYVNNG 489 G VAVKKL ++ + ++F E+E + ++H N+V+ G C +R L+ EY+ G Sbjct: 876 GEVVAVKKLQHSTEEHLRDFEREIEILKSLQHDNIVKYKGVCYSAGRRNLRLIMEYLPYG 935 Query: 490 NLEQWLHGAMSHRGSLTWEARIKILLGTAKALAYL 594 +L +L H+ + + ++ K + YL Sbjct: 936 SLRDYL---QKHKERIDHKKLLQYTSQICKGMEYL 967 Score = 37.4 bits (85), Expect = 0.034 Identities = 29/97 (29%), Positives = 45/97 (46%) Frame = +1 Query: 319 TPVAVKKLLNNLGQAEKEFRVEVEAIGHVRHKNLVRLLGYCVEGTQRILVYEYVNNGNLE 498 T V +K L + F + + HK+LV G CV G + ILV E+V G+L+ Sbjct: 576 TEVLLKVLDKAHRNYSESFFEAASMMSQLSHKHLVLNYGVCVCGEENILVQEFVKFGSLD 635 Query: 499 QWLHGAMSHRGSLTWEARIKILLGTAKALAYLHEAIE 609 +L + ++ W+ LG AK LA+ +E Sbjct: 636 TYLK-KNKNSINILWK------LGVAKQLAWAMHFLE 665
>EPHA3_CHICK (P29318) Ephrin type-A receptor 3 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor ETK1) (CEK4) Length = 983 Score = 42.0 bits (97), Expect = 0.001 Identities = 29/95 (30%), Positives = 45/95 (47%), Gaps = 3/95 (3%) Frame = +1 Query: 325 VAVKKLLNNLGQAEKE---FRVEVEAIGHVRHKNLVRLLGYCVEGTQRILVYEYVNNGNL 495 VA+K L G EK+ F E +G H N++RL G + ++V EY+ NG+L Sbjct: 650 VAIKTL--KAGYTEKQRRDFLGEASIMGQFDHPNIIRLEGVVTKSKPVMIVTEYMENGSL 707 Query: 496 EQWLHGAMSHRGSLTWEARIKILLGTAKALAYLHE 600 + +L H T + +L G A + YL + Sbjct: 708 DSFLR---KHDAQFTVIQLVGMLRGIASGMKYLSD 739
>DDR1_RAT (Q63474) Epithelial discoidin domain-containing receptor 1| precursor (EC 2.7.10.1) (Epithelial discoidin domain receptor 1) (Tyrosine kinase DDR) (Discoidin receptor tyrosine kinase) (Tyrosine-protein kinase CAK) (Cell adhesion kinase) (Protein- Length = 910 Score = 42.0 bits (97), Expect = 0.001 Identities = 22/62 (35%), Positives = 38/62 (61%), Gaps = 1/62 (1%) Frame = +1 Query: 325 VAVKKLLNNLGQ-AEKEFRVEVEAIGHVRHKNLVRLLGYCVEGTQRILVYEYVNNGNLEQ 501 VAVK L + + A +F EV+ + ++ N++RLLG CV+ ++ +Y+ NG+L Q Sbjct: 649 VAVKILRPDATKNARNDFLKEVKIMSRLKDLNIIRLLGVCVQDDPLCMITDYMENGDLNQ 708 Query: 502 WL 507 +L Sbjct: 709 FL 710
>EPHA5_MOUSE (Q60629) Ephrin type-A receptor 5 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EHK-1) (EPH homology kinase 1) (Brain-specific kinase) (CEK-7) Length = 877 Score = 42.0 bits (97), Expect = 0.001 Identities = 29/96 (30%), Positives = 47/96 (48%), Gaps = 3/96 (3%) Frame = +1 Query: 322 PVAVKKLLNNLGQAEKE---FRVEVEAIGHVRHKNLVRLLGYCVEGTQRILVYEYVNNGN 492 PVA+K L +G EK+ F E +G H N++ L G + ++V EY+ NG+ Sbjct: 542 PVAIKTL--KVGYTEKQRRDFLGEASIMGQFDHPNIIHLEGVVTKSKPVMIVTEYMENGS 599 Query: 493 LEQWLHGAMSHRGSLTWEARIKILLGTAKALAYLHE 600 L+ +L + G T + +L G A + YL + Sbjct: 600 LDTFL---KKNDGQFTVIQLVGMLRGIAAGMKYLSD 632
>TYK2_HUMAN (P29597) Non-receptor tyrosine-protein kinase TYK2 (EC 2.7.10.2)| Length = 1187 Score = 41.6 bits (96), Expect = 0.002 Identities = 23/67 (34%), Positives = 35/67 (52%) Frame = +1 Query: 394 IGHVRHKNLVRLLGYCVEGTQRILVYEYVNNGNLEQWLHGAMSHRGSLTWEARIKILLGT 573 + V H +L + G CV G + I+V EYV +G L+ WL RG + ++ + Sbjct: 662 MSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR---RERGHVPMAWKMVVAQQL 718 Query: 574 AKALAYL 594 A AL+YL Sbjct: 719 ASALSYL 725
>CSK_CHICK (P41239) Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase)| Length = 450 Score = 41.6 bits (96), Expect = 0.002 Identities = 31/94 (32%), Positives = 46/94 (48%), Gaps = 1/94 (1%) Frame = +1 Query: 316 GTPVAVKKLLNNLGQAEKEFRVEVEAIGHVRHKNLVRLLGYCVEGTQRI-LVYEYVNNGN 492 G VAVK + N+ + F E + +RH NLV+LLG VE + +V EY+ G+ Sbjct: 216 GNKVAVKCIKNDA--TAQAFLAEASVMTQLRHSNLVQLLGVIVEEKSGLYIVTEYMAKGS 273 Query: 493 LEQWLHGAMSHRGSLTWEARIKILLGTAKALAYL 594 L +L R L + +K L +A+ YL Sbjct: 274 LVDYLRS--RGRSVLGGDCLLKFSLDVCEAMEYL 305
>ROR2_DROME (Q9V6K3) Tyrosine-protein kinase transmembrane receptor Ror2| precursor (EC 2.7.10.1) (Neurospecific receptor tyrosine kinase) Length = 724 Score = 41.6 bits (96), Expect = 0.002 Identities = 23/62 (37%), Positives = 35/62 (56%), Gaps = 1/62 (1%) Frame = +1 Query: 325 VAVKKLLNNLG-QAEKEFRVEVEAIGHVRHKNLVRLLGYCVEGTQRILVYEYVNNGNLEQ 501 VAVK L ++ Q + +F E + H N+VRLLG C G L++EY+ G+L + Sbjct: 472 VAVKMLKDDASDQMQMDFEREACLLAEFDHPNIVRLLGVCALGRPMCLLFEYMAPGDLSE 531 Query: 502 WL 507 +L Sbjct: 532 FL 533
>KIN31_CAEEL (P34265) Probable tyrosine-protein kinase kin-31 (EC 2.7.10.2)| Length = 437 Score = 41.6 bits (96), Expect = 0.002 Identities = 30/93 (32%), Positives = 48/93 (51%), Gaps = 2/93 (2%) Frame = +1 Query: 325 VAVKKL-LNNLGQAE-KEFRVEVEAIGHVRHKNLVRLLGYCVEGTQRILVYEYVNNGNLE 498 VAVK++ + +G+ + K+F +E + ++ H N+VR LG V LV E G L+ Sbjct: 160 VAVKQVKTDGIGKDQIKDFLMEARTMRNLGHPNIVRFLGIAVLQEPLFLVMELATGGALD 219 Query: 499 QWLHGAMSHRGSLTWEARIKILLGTAKALAYLH 597 +L H L + R ++LL A L Y+H Sbjct: 220 SYL----KHNELLPIDKRHEMLLQAAWGLEYIH 248
>FGFR2_XENLA (Q03364) Fibroblast growth factor receptor 2 precursor (EC| 2.7.10.1) (FGFR-2) Length = 813 Score = 41.6 bits (96), Expect = 0.002 Identities = 24/63 (38%), Positives = 37/63 (58%), Gaps = 2/63 (3%) Frame = +1 Query: 325 VAVKKLLNNLGQAEKEFRV-EVEAIGHV-RHKNLVRLLGYCVEGTQRILVYEYVNNGNLE 498 VAVK L +N + + V E+E + + +HKN++ LLG C +G ++ EY GNL Sbjct: 504 VAVKMLKDNATEKDLADLVSEMEMMKMIGKHKNIINLLGACTQGGTLYVIVEYAAKGNLR 563 Query: 499 QWL 507 Q+L Sbjct: 564 QYL 566
>JAK1_HUMAN (P23458) Tyrosine-protein kinase JAK1 (EC 2.7.10.2) (Janus kinase| 1) (JAK-1) Length = 1142 Score = 41.2 bits (95), Expect = 0.002 Identities = 23/66 (34%), Positives = 35/66 (53%) Frame = +1 Query: 403 VRHKNLVRLLGYCVEGTQRILVYEYVNNGNLEQWLHGAMSHRGSLTWEARIKILLGTAKA 582 V HK++V L G CV + I+V E+V G L+ ++H LT + K+ A A Sbjct: 633 VSHKHIVYLYGVCVRDVENIMVEEFVEGGPLDLFMH---RKSDVLTTPWKFKVAKQLASA 689 Query: 583 LAYLHE 600 L+YL + Sbjct: 690 LSYLED 695 Score = 38.1 bits (87), Expect = 0.020 Identities = 25/96 (26%), Positives = 50/96 (52%), Gaps = 3/96 (3%) Frame = +1 Query: 316 GTPVAVKKLLNNLGQAE-KEFRVEVEAIGHVRHKNLVRLLGYCVE--GTQRILVYEYVNN 486 G VAVK L G + + E+E + ++ H+N+V+ G C E G L+ E++ + Sbjct: 890 GEQVAVKSLKPESGGNHIADLKKEIEILRNLYHENIVKYKGICTEDGGNGIKLIMEFLPS 949 Query: 487 GNLEQWLHGAMSHRGSLTWEARIKILLGTAKALAYL 594 G+L+++L ++ + + ++K + K + YL Sbjct: 950 GSLKEYL---PKNKNKINLKQQLKYAVQICKGMDYL 982
>ABL1_CAEEL (P03949) Tyrosine-protein kinase abl-1 (EC 2.7.10.2)| Length = 1224 Score = 41.2 bits (95), Expect = 0.002 Identities = 23/61 (37%), Positives = 33/61 (54%) Frame = +1 Query: 325 VAVKKLLNNLGQAEKEFRVEVEAIGHVRHKNLVRLLGYCVEGTQRILVYEYVNNGNLEQW 504 +AVK L + EF E + + HKNLVRLLG C ++ E++ NGNL ++ Sbjct: 337 IAVKALKED-AMPLHEFLAEAAIMKDLHHKNLVRLLGVCTHEAPFYIITEFMCNGNLLEY 395 Query: 505 L 507 L Sbjct: 396 L 396
>CAD96_DROME (Q9VBW3) Tyrosine kinase receptor Cad96Ca precursor (EC 2.7.10.1)| (Cadherin 96Ca) (Tyrosine kinase receptor HD-14) Length = 773 Score = 41.2 bits (95), Expect = 0.002 Identities = 24/72 (33%), Positives = 39/72 (54%), Gaps = 2/72 (2%) Frame = +1 Query: 319 TPVAVKKLLNNLGQAE-KEFRVEVEAIGHVR-HKNLVRLLGYCVEGTQRILVYEYVNNGN 492 T VAVK L + + + K+ E+E + + H N+V LLG C + ++ EYVN G Sbjct: 499 TTVAVKTLKESATEVDRKDLLSELEVMKSLEPHINVVHLLGCCTDKDPTFVILEYVNRGK 558 Query: 493 LEQWLHGAMSHR 528 L+ +L + + R Sbjct: 559 LQTYLRSSRAER 570
>TXK_MOUSE (P42682) Tyrosine-protein kinase TXK (EC 2.7.10.2) (PTK-RL-18)| (Resting lymphocyte kinase) Length = 527 Score = 41.2 bits (95), Expect = 0.002 Identities = 25/94 (26%), Positives = 46/94 (48%) Frame = +1 Query: 322 PVAVKKLLNNLGQAEKEFRVEVEAIGHVRHKNLVRLLGYCVEGTQRILVYEYVNNGNLEQ 501 PVA+K + N +E++F E + + + H LV+L G C++ +V E++ NG L Sbjct: 295 PVAIKAI-NEGSMSEEDFIEEAKVMMKLSHSRLVQLYGVCIQQKPLYIVTEFMENGCLLD 353 Query: 502 WLHGAMSHRGSLTWEARIKILLGTAKALAYLHEA 603 +L +G L + + + +AYL + Sbjct: 354 YLR---ERKGQLQKALLLSMCQDICEGMAYLERS 384
>ERBB4_HUMAN (Q15303) Receptor tyrosine-protein kinase erbB-4 precursor (EC| 2.7.10.1) (p180erbB4) (Tyrosine kinase-type cell surface receptor HER4) Length = 1308 Score = 41.2 bits (95), Expect = 0.002 Identities = 30/94 (31%), Positives = 50/94 (53%), Gaps = 1/94 (1%) Frame = +1 Query: 322 PVAVKKLLNNLG-QAEKEFRVEVEAIGHVRHKNLVRLLGYCVEGTQRILVYEYVNNGNLE 498 PVA+K L G +A EF E + + H +LVRLLG C+ T + LV + + +G L Sbjct: 747 PVAIKILNETTGPKANVEFMDEALIMASMDHPHLVRLLGVCLSPTIQ-LVTQLMPHGCLL 805 Query: 499 QWLHGAMSHRGSLTWEARIKILLGTAKALAYLHE 600 +++H H+ ++ + + + AK + YL E Sbjct: 806 EYVH---EHKDNIGSQLLLNWCVQIAKGMMYLEE 836
>EGFR_DROME (P04412) Epidermal growth factor receptor precursor (EC 2.7.10.1)| (Egfr) (Gurken receptor) (Protein torpedo) (Drosophila relative of ERBB) Length = 1426 Score = 41.2 bits (95), Expect = 0.002 Identities = 30/97 (30%), Positives = 50/97 (51%), Gaps = 4/97 (4%) Frame = +1 Query: 322 PVAVKKLLNNLG-QAEKEFRVEVEAIGHVRHKNLVRLLGYCVEGTQRILVYEYVNNGNLE 498 PVA+K+LL + G ++ +EF E + H NL++LL C+ +Q +L+ + + G L Sbjct: 967 PVAIKELLKSTGAESSEEFLREAYIMASEEHVNLLKLLAVCM-SSQMMLITQLMPLGCLL 1025 Query: 499 QWLHGAMSHRGS---LTWEARIKILLGTAKALAYLHE 600 ++ GS L W +I AK ++YL E Sbjct: 1026 DYVRNNRDKIGSKALLNWSTQI------AKGMSYLEE 1056
>M3K1_MOUSE (P53349) Mitogen-activated protein kinase kinase kinase 1 (EC| 2.7.11.25) (MAPK/ERK kinase kinase 1) (MEK kinase 1) (MEKK 1) Length = 1493 Score = 41.2 bits (95), Expect = 0.002 Identities = 29/101 (28%), Positives = 52/101 (51%), Gaps = 6/101 (5%) Frame = +1 Query: 316 GTPVAVKKL--LNNLGQAEKE----FRVEVEAIGHVRHKNLVRLLGYCVEGTQRILVYEY 477 GT +AVK++ + N ++E R E+ +GH+ H N++R+LG E + L E+ Sbjct: 1247 GTLMAVKQVTYVRNTSSEQEEVVEALREEIRMMGHLNHPNIIRMLGATCEKSNYNLFIEW 1306 Query: 478 VNNGNLEQWLHGAMSHRGSLTWEARIKILLGTAKALAYLHE 600 + G++ L + + S+ ++L G L+YLHE Sbjct: 1307 MAGGSVAHLLSKYGAFKESVVINYTEQLLRG----LSYLHE 1343
>EPHA5_RAT (P54757) Ephrin type-A receptor 5 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EHK-1) (EPH homology kinase 1) Length = 1005 Score = 41.2 bits (95), Expect = 0.002 Identities = 29/96 (30%), Positives = 46/96 (47%), Gaps = 3/96 (3%) Frame = +1 Query: 322 PVAVKKLLNNLGQAEKE---FRVEVEAIGHVRHKNLVRLLGYCVEGTQRILVYEYVNNGN 492 PVA K L +G EK+ F E +G H N++ L G + ++V EY+ NG+ Sbjct: 705 PVATKTL--KVGYTEKQRRDFLSEASIMGQFDHPNIIHLEGVVTKSKPVMIVTEYMENGS 762 Query: 493 LEQWLHGAMSHRGSLTWEARIKILLGTAKALAYLHE 600 L+ +L + G T + +L G A + YL + Sbjct: 763 LDTFL---KKNDGQFTVIQLVGMLRGIAAGMKYLSD 795
>LIMK1_DROME (Q8IR79) LIM domain kinase 1 (EC 2.7.11.1) (LIMK-1) (dLIMK)| Length = 1257 Score = 40.8 bits (94), Expect = 0.003 Identities = 23/95 (24%), Positives = 49/95 (51%) Frame = +1 Query: 313 NGTPVAVKKLLNNLGQAEKEFRVEVEAIGHVRHKNLVRLLGYCVEGTQRILVYEYVNNGN 492 +G + +K+L +A++ F EV + + H+++++ +G + + +V EYV G Sbjct: 423 SGEVMVLKELHRADEEAQRNFIKEVAVLRLLDHRHVLKFIGVLYKDKKLHMVTEYVAGGC 482 Query: 493 LEQWLHGAMSHRGSLTWEARIKILLGTAKALAYLH 597 L++ +H L W R+++ A ++YLH Sbjct: 483 LKELIHDPAQ---VLPWPQRVRLARDIACGMSYLH 514
>LIMK1_CHICK (Q8QFP8) LIM domain kinase 1 (EC 2.7.11.1) (LIMK-1) (chLIMK1)| Length = 662 Score = 40.8 bits (94), Expect = 0.003 Identities = 22/94 (23%), Positives = 43/94 (45%) Frame = +1 Query: 316 GTPVAVKKLLNNLGQAEKEFRVEVEAIGHVRHKNLVRLLGYCVEGTQRILVYEYVNNGNL 495 G + +K+L+ + ++ F EV+ + + H N+++ +G + + + EY+ G L Sbjct: 369 GEVMVMKELIRFDEETQRTFLKEVKVMRCLEHPNVLKFIGVLYKEKRLNFITEYIKGGTL 428 Query: 496 EQWLHGAMSHRGSLTWEARIKILLGTAKALAYLH 597 + SH W R+ A +AYLH Sbjct: 429 RGLIKSMDSH---YPWSQRVSFAKDIAAGMAYLH 459
>CSK_RAT (P32577) Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase)| Length = 450 Score = 40.8 bits (94), Expect = 0.003 Identities = 31/94 (32%), Positives = 46/94 (48%), Gaps = 1/94 (1%) Frame = +1 Query: 316 GTPVAVKKLLNNLGQAEKEFRVEVEAIGHVRHKNLVRLLGYCVEGTQRI-LVYEYVNNGN 492 G VAVK + N+ + F E + +RH NLV+LLG VE + +V EY+ G+ Sbjct: 216 GNKVAVKCIKNDA--TAQAFLAEASVMTQLRHSNLVQLLGVIVEEKGGLYIVTEYMAKGS 273 Query: 493 LEQWLHGAMSHRGSLTWEARIKILLGTAKALAYL 594 L +L R L + +K L +A+ YL Sbjct: 274 LVDYLRS--RGRSVLGGDCLLKFSLDVCEAMEYL 305
>CSK_HUMAN (P41240) Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase)| (Protein-tyrosine kinase CYL) Length = 450 Score = 40.8 bits (94), Expect = 0.003 Identities = 31/94 (32%), Positives = 46/94 (48%), Gaps = 1/94 (1%) Frame = +1 Query: 316 GTPVAVKKLLNNLGQAEKEFRVEVEAIGHVRHKNLVRLLGYCVEGTQRI-LVYEYVNNGN 492 G VAVK + N+ + F E + +RH NLV+LLG VE + +V EY+ G+ Sbjct: 216 GNKVAVKCIKNDA--TAQAFLAEASVMTQLRHSNLVQLLGVIVEEKGGLYIVTEYMAKGS 273 Query: 493 LEQWLHGAMSHRGSLTWEARIKILLGTAKALAYL 594 L +L R L + +K L +A+ YL Sbjct: 274 LVDYLRS--RGRSVLGGDCLLKFSLDVCEAMEYL 305
>JAK2_HUMAN (O60674) Tyrosine-protein kinase JAK2 (EC 2.7.10.2) (Janus kinase 2)| (JAK-2) Length = 1132 Score = 40.8 bits (94), Expect = 0.003 Identities = 22/66 (33%), Positives = 38/66 (57%), Gaps = 2/66 (3%) Frame = +1 Query: 316 GTPVAVKKLLNNLGQAEKEFRVEVEAIGHVRHKNLVRLLGYCVEGTQR--ILVYEYVNNG 489 G VAVKKL ++ + ++F E+E + ++H N+V+ G C +R L+ EY+ G Sbjct: 876 GEVVAVKKLQHSTEEHLRDFEREIEILKSLQHDNIVKYKGVCYSAGRRNLKLIMEYLPYG 935 Query: 490 NLEQWL 507 +L +L Sbjct: 936 SLRDYL 941 Score = 34.3 bits (77), Expect = 0.29 Identities = 21/63 (33%), Positives = 31/63 (49%) Frame = +1 Query: 319 TPVAVKKLLNNLGQAEKEFRVEVEAIGHVRHKNLVRLLGYCVEGTQRILVYEYVNNGNLE 498 T V +K L + F + + HK+LV G CV G + ILV E+V G+L+ Sbjct: 576 TEVLLKVLDKAHRNYSESFFEAASMMSKLSHKHLVLNYGVCVCGDENILVQEFVKFGSLD 635 Query: 499 QWL 507 +L Sbjct: 636 TYL 638
>ANPRB_RAT (P16067) Atrial natriuretic peptide receptor B precursor (ANP-B)| (ANPRB) (GC-B) (Guanylate cyclase B) (EC 4.6.1.2) (NPR-B) (Atrial natriuretic peptide B-type receptor) Length = 1047 Score = 40.8 bits (94), Expect = 0.003 Identities = 24/97 (24%), Positives = 47/97 (48%) Frame = +1 Query: 316 GTPVAVKKLLNNLGQAEKEFRVEVEAIGHVRHKNLVRLLGYCVEGTQRILVYEYVNNGNL 495 G VA+K + + ++ E++ + V+ +L R +G C++ +V EY G+L Sbjct: 545 GNVVAIKHVNKKRIELTRQVLFELKHMRDVQFNHLTRFIGACIDPPNICIVTEYCPRGSL 604 Query: 496 EQWLHGAMSHRGSLTWEARIKILLGTAKALAYLHEAI 606 + L + +L W R ++ K +A+LH +I Sbjct: 605 QDILE---NDSINLDWMFRYSLINDLVKGMAFLHNSI 638
>ANPRB_MOUSE (Q6VVW5) Atrial natriuretic peptide receptor B precursor (ANP-B)| (ANPRB) (GC-B) (Guanylate cyclase B) (EC 4.6.1.2) (NPR-B) (Atrial natriuretic peptide B-type receptor) Length = 1047 Score = 40.8 bits (94), Expect = 0.003 Identities = 24/97 (24%), Positives = 47/97 (48%) Frame = +1 Query: 316 GTPVAVKKLLNNLGQAEKEFRVEVEAIGHVRHKNLVRLLGYCVEGTQRILVYEYVNNGNL 495 G VA+K + + ++ E++ + V+ +L R +G C++ +V EY G+L Sbjct: 545 GNVVAIKHVNKKRIELTRQVLFELKHMRDVQFNHLTRFIGACIDPPNICIVTEYCPRGSL 604 Query: 496 EQWLHGAMSHRGSLTWEARIKILLGTAKALAYLHEAI 606 + L + +L W R ++ K +A+LH +I Sbjct: 605 QDILE---NDSINLDWMFRYSLINDLVKGMAFLHNSI 638
>ANPRB_HUMAN (P20594) Atrial natriuretic peptide receptor B precursor (ANP-B)| (ANPRB) (GC-B) (Guanylate cyclase B) (EC 4.6.1.2) (NPR-B) (Atrial natriuretic peptide B-type receptor) Length = 1047 Score = 40.8 bits (94), Expect = 0.003 Identities = 24/97 (24%), Positives = 47/97 (48%) Frame = +1 Query: 316 GTPVAVKKLLNNLGQAEKEFRVEVEAIGHVRHKNLVRLLGYCVEGTQRILVYEYVNNGNL 495 G VA+K + + ++ E++ + V+ +L R +G C++ +V EY G+L Sbjct: 545 GNVVAIKHVNKKRIELTRQVLFELKHMRDVQFNHLTRFIGACIDPPNICIVTEYCPRGSL 604 Query: 496 EQWLHGAMSHRGSLTWEARIKILLGTAKALAYLHEAI 606 + L + +L W R ++ K +A+LH +I Sbjct: 605 QDILE---NDSINLDWMFRYSLINDLVKGMAFLHNSI 638
>ANPRB_BOVIN (P46197) Atrial natriuretic peptide receptor B precursor (ANP-B)| (ANPRB) (GC-B) (Guanylate cyclase B) (EC 4.6.1.2) (NPR-B) (Atrial natriuretic peptide B-type receptor) Length = 1047 Score = 40.8 bits (94), Expect = 0.003 Identities = 24/97 (24%), Positives = 47/97 (48%) Frame = +1 Query: 316 GTPVAVKKLLNNLGQAEKEFRVEVEAIGHVRHKNLVRLLGYCVEGTQRILVYEYVNNGNL 495 G VA+K + + ++ E++ + V+ +L R +G C++ +V EY G+L Sbjct: 545 GNVVAIKHVNKKRIELTRQVLFELKHMRDVQFNHLTRFIGACIDPPNICIVTEYCPRGSL 604 Query: 496 EQWLHGAMSHRGSLTWEARIKILLGTAKALAYLHEAI 606 + L + +L W R ++ K +A+LH +I Sbjct: 605 QDILE---NDSINLDWMFRYSLINDLVKGMAFLHNSI 638
>EPHA5_HUMAN (P54756) Ephrin type-A receptor 5 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EHK-1) (EPH homology kinase 1) (Receptor protein-tyrosine kinase HEK7) Length = 1037 Score = 40.8 bits (94), Expect = 0.003 Identities = 28/96 (29%), Positives = 47/96 (48%), Gaps = 3/96 (3%) Frame = +1 Query: 322 PVAVKKLLNNLGQAEKE---FRVEVEAIGHVRHKNLVRLLGYCVEGTQRILVYEYVNNGN 492 PVA+K L +G EK+ F E +G H N++ L G + ++V EY+ NG+ Sbjct: 703 PVAIKTL--KVGYTEKQRRDFLGEASIMGQFDHPNIIHLEGVVTKSKPVMIVTEYMENGS 760 Query: 493 LEQWLHGAMSHRGSLTWEARIKILLGTAKALAYLHE 600 L+ +L + G T + +L G + + YL + Sbjct: 761 LDTFL---KKNDGQFTVIQLVGMLRGISAGMKYLSD 793
>EPHB4_MOUSE (P54761) Ephrin type-B receptor 4 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor MDK-2) (Developmental kinase 2) (Tyrosine kinase MYK-1) Length = 987 Score = 40.4 bits (93), Expect = 0.004 Identities = 26/93 (27%), Positives = 44/93 (47%), Gaps = 1/93 (1%) Frame = +1 Query: 325 VAVKKLLNNLGQAEK-EFRVEVEAIGHVRHKNLVRLLGYCVEGTQRILVYEYVNNGNLEQ 501 VA+K L + ++ EF E +G H N++RL G +++ E++ NG L+ Sbjct: 644 VAIKTLKGGYTERQRREFLSEASIMGQFEHPNIIRLEGVVTNSVPVMILTEFMENGALDS 703 Query: 502 WLHGAMSHRGSLTWEARIKILLGTAKALAYLHE 600 +L + G T + +L G A + YL E Sbjct: 704 FLR---LNDGQFTVIQLVGMLRGIASGMRYLAE 733
>CSK_MOUSE (P41241) Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase)| (Protein-tyrosine kinase MPK-2) (p50CSK) Length = 450 Score = 40.4 bits (93), Expect = 0.004 Identities = 31/94 (32%), Positives = 46/94 (48%), Gaps = 1/94 (1%) Frame = +1 Query: 316 GTPVAVKKLLNNLGQAEKEFRVEVEAIGHVRHKNLVRLLGYCVEGTQRI-LVYEYVNNGN 492 G VAVK + N+ + F E + +RH NLV+LLG VE + +V EY+ G+ Sbjct: 216 GNKVAVKCIKNDA--TAQAFLAEASVMTQLRHSNLVQLLGVIVEEKGGLYIVTEYMAKGS 273 Query: 493 LEQWLHGAMSHRGSLTWEARIKILLGTAKALAYL 594 L +L R L + +K L +A+ YL Sbjct: 274 LVDYLRS--RGRSVLGGDCLLKFSLDVLEAMEYL 305
>DDR2_MOUSE (Q62371) Discoidin domain-containing receptor 2 precursor (EC| 2.7.10.1) (Discoidin domain receptor 2) (Receptor protein-tyrosine kinase TKT) (Tyrosine-protein kinase TYRO 10) (Neurotrophic tyrosine kinase, receptor-related 3) (CD167b antigen) Length = 854 Score = 40.4 bits (93), Expect = 0.004 Identities = 20/62 (32%), Positives = 36/62 (58%), Gaps = 1/62 (1%) Frame = +1 Query: 325 VAVKKLLNNLGQ-AEKEFRVEVEAIGHVRHKNLVRLLGYCVEGTQRILVYEYVNNGNLEQ 501 VAVK L + + A +F E++ + ++ N++RLL C+ ++ EY+ NG+L Q Sbjct: 605 VAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIRLLAVCITEDPLCMITEYMENGDLNQ 664 Query: 502 WL 507 +L Sbjct: 665 FL 666
>KYK2_DICDI (P18161) Tyrosine-protein kinase 2 (EC 2.7.10.2) (Fragment)| Length = 410 Score = 40.0 bits (92), Expect = 0.005 Identities = 27/96 (28%), Positives = 47/96 (48%), Gaps = 2/96 (2%) Frame = +1 Query: 316 GTPVAVKKL--LNNLGQAEKEFRVEVEAIGHVRHKNLVRLLGYCVEGTQRILVYEYVNNG 489 G VA+KKL + + Q ++ F EV+ + H+N+V +G C + ++ EY+ G Sbjct: 129 GIHVAIKKLKIIGDEEQFKERFIREVQNLKKGNHQNIVMFIGACYKPA--CIITEYMAGG 186 Query: 490 NLEQWLHGAMSHRGSLTWEARIKILLGTAKALAYLH 597 +L LH S + + + + + T AL LH Sbjct: 187 SLYNILHNPNSSTPKVKYSFPLVLKMATDMALGLLH 222
>FPS_FUJSV (P00530) Tyrosine-protein kinase transforming protein FPS (EC| 2.7.10.2) Length = 873 Score = 40.0 bits (92), Expect = 0.005 Identities = 28/95 (29%), Positives = 43/95 (45%), Gaps = 1/95 (1%) Frame = +1 Query: 313 NGTPVAVKKLLNNLG-QAEKEFRVEVEAIGHVRHKNLVRLLGYCVEGTQRILVYEYVNNG 489 + TPVAVK L + + +F E + H N+VRL+G C + +V E V G Sbjct: 634 DNTPVAVKSCRETLPPELKAKFLQEARILKQCNHPNIVRLIGVCTQKQPIYIVMELVQGG 693 Query: 490 NLEQWLHGAMSHRGSLTWEARIKILLGTAKALAYL 594 + +L S L + IK++ A + YL Sbjct: 694 DFLSFLR---SKGPRLKMKKLIKMMENAAAGMEYL 725
>EPA4A_BRARE (O13148) Ephrin type-A receptor 4a (EC 2.7.10.1) (Tyrosine-protein| kinase receptor ZEK2) (EPH-like kinase 2) (Fragment) Length = 292 Score = 40.0 bits (92), Expect = 0.005 Identities = 26/93 (27%), Positives = 45/93 (48%), Gaps = 1/93 (1%) Frame = +1 Query: 325 VAVKKL-LNNLGQAEKEFRVEVEAIGHVRHKNLVRLLGYCVEGTQRILVYEYVNNGNLEQ 501 VA+K L + ++F E +G H N++RL G + +++ EY+ NG+L+ Sbjct: 24 VAIKTLKAGYTDKQRRDFLSEASIMGQFDHPNIIRLEGVVTKCKPVMIITEYMENGSLDA 83 Query: 502 WLHGAMSHRGSLTWEARIKILLGTAKALAYLHE 600 +L + G T + IL G A + YL + Sbjct: 84 FLR---KNDGRFTVIQLVGILRGIASGMKYLSD 113
>EPHB4_HUMAN (P54760) Ephrin type-B receptor 4 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor HTK) Length = 987 Score = 40.0 bits (92), Expect = 0.005 Identities = 26/93 (27%), Positives = 44/93 (47%), Gaps = 1/93 (1%) Frame = +1 Query: 325 VAVKKLLNNLGQAEK-EFRVEVEAIGHVRHKNLVRLLGYCVEGTQRILVYEYVNNGNLEQ 501 VA+K L + ++ EF E +G H N++RL G +++ E++ NG L+ Sbjct: 644 VAIKTLKGGYTERQRREFLSEASIMGQFEHPNIIRLEGVVTNSMPVMILTEFMENGALDS 703 Query: 502 WLHGAMSHRGSLTWEARIKILLGTAKALAYLHE 600 +L + G T + +L G A + YL E Sbjct: 704 FLR---LNDGQFTVIQLVGMLRGIASGMRYLAE 733
>ABL2_HUMAN (P42684) Tyrosine-protein kinase ABL2 (EC 2.7.10.2) (Abelson murine| leukemia viral oncogene homolog 2) (Tyrosine kinase ARG) Length = 1182 Score = 40.0 bits (92), Expect = 0.005 Identities = 29/92 (31%), Positives = 45/92 (48%) Frame = +1 Query: 325 VAVKKLLNNLGQAEKEFRVEVEAIGHVRHKNLVRLLGYCVEGTQRILVYEYVNNGNLEQW 504 VAVK L + + E EF E + ++H NLV+LLG C +V EY+ GNL + Sbjct: 314 VAVKTLKEDTMEVE-EFLKEAAVMKEIKHPNLVQLLGVCTLEPPFYIVTEYMPYGNLLDY 372 Query: 505 LHGAMSHRGSLTWEARIKILLGTAKALAYLHE 600 L +R +T + + + A+ YL + Sbjct: 373 LREC--NREEVTAVVLLYMATQISSAMEYLEK 402
>RIPK1_HUMAN (Q13546) Receptor-interacting serine/threonine-protein kinase 1 (EC| 2.7.11.1) (Serine/threonine-protein kinase RIP) (Cell death protein RIP) (Receptor-interacting protein) Length = 671 Score = 40.0 bits (92), Expect = 0.005 Identities = 24/72 (33%), Positives = 38/72 (52%) Frame = +1 Query: 382 EVEAIGHVRHKNLVRLLGYCVEGTQRILVYEYVNNGNLEQWLHGAMSHRGSLTWEARIKI 561 E + + +RH +V+LLG +E + LV EY+ GNL L MS S+ + +I Sbjct: 63 EAKMMNRLRHSRVVKLLGVIIEEGKYSLVMEYMEKGNLMHVLKAEMSTPLSV----KGRI 118 Query: 562 LLGTAKALAYLH 597 +L + + YLH Sbjct: 119 ILEIIEGMCYLH 130
>EPB1A_XENLA (Q91571) Ephrin type-B receptor 1-A precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor XEK) Length = 985 Score = 40.0 bits (92), Expect = 0.005 Identities = 25/93 (26%), Positives = 45/93 (48%), Gaps = 1/93 (1%) Frame = +1 Query: 325 VAVKKLLNNLGQAEK-EFRVEVEAIGHVRHKNLVRLLGYCVEGTQRILVYEYVNNGNLEQ 501 VA+K L + ++ +F E +G H N++RL G + +++ E++ NG L+ Sbjct: 649 VAIKTLKAGYSEKQRRDFLSEASIMGQFDHPNIIRLEGVVTKSRPVMIITEFMENGALDS 708 Query: 502 WLHGAMSHRGSLTWEARIKILLGTAKALAYLHE 600 +L + G T + +L G A + YL E Sbjct: 709 FLR---QNDGQFTVIQLVGMLRGIAAGMKYLSE 738
>EPHB2_HUMAN (P29323) Ephrin type-B receptor 2 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EPH-3) (DRT) (Receptor protein-tyrosine kinase HEK5) (ERK) (NY-REN-47 antigen) Length = 1055 Score = 40.0 bits (92), Expect = 0.005 Identities = 24/91 (26%), Positives = 46/91 (50%), Gaps = 1/91 (1%) Frame = +1 Query: 325 VAVKKLLNNLGQAEK-EFRVEVEAIGHVRHKNLVRLLGYCVEGTQRILVYEYVNNGNLEQ 501 VA+K L + + ++ +F E +G H N++ L G + T +++ E++ NG+L+ Sbjct: 650 VAIKTLKSGYTEKQRRDFLSEASIMGQFDHPNVIHLEGVVTKSTPVMIITEFMENGSLDS 709 Query: 502 WLHGAMSHRGSLTWEARIKILLGTAKALAYL 594 +L + G T + +L G A + YL Sbjct: 710 FLR---QNDGQFTVIQLVGMLRGIAAGMKYL 737
>TXK_HUMAN (P42681) Tyrosine-protein kinase TXK (EC 2.7.10.2)| Length = 527 Score = 40.0 bits (92), Expect = 0.005 Identities = 22/86 (25%), Positives = 42/86 (48%) Frame = +1 Query: 337 KLLNNLGQAEKEFRVEVEAIGHVRHKNLVRLLGYCVEGTQRILVYEYVNNGNLEQWLHGA 516 K +N +E++F E + + + H LV+L G C++ +V E++ NG L +L Sbjct: 299 KAINEGSMSEEDFIEEAKVMMKLSHSKLVQLYGVCIQRKPLYIVTEFMENGCLLNYLR-- 356 Query: 517 MSHRGSLTWEARIKILLGTAKALAYL 594 ++G L E + + + + YL Sbjct: 357 -ENKGKLRKEMLLSVCQDICEGMEYL 381
>EPB1B_XENLA (Q91736) Ephrin type-B receptor 1-B (EC 2.7.10.1) (Tyrosine-protein| kinase receptor XELK) (Fragment) Length = 902 Score = 40.0 bits (92), Expect = 0.005 Identities = 25/93 (26%), Positives = 45/93 (48%), Gaps = 1/93 (1%) Frame = +1 Query: 325 VAVKKLLNNLGQAEK-EFRVEVEAIGHVRHKNLVRLLGYCVEGTQRILVYEYVNNGNLEQ 501 VA+K L + ++ +F E +G H N++RL G + +++ E++ NG L+ Sbjct: 566 VAIKTLKAGYSEKQRRDFLSEASIMGQFDHPNIIRLEGVVTKSRPVMIITEFMENGALDS 625 Query: 502 WLHGAMSHRGSLTWEARIKILLGTAKALAYLHE 600 +L + G T + +L G A + YL E Sbjct: 626 FLR---QNDGQFTVIQLVGMLRGIAAGMKYLSE 655
>EPHB2_MOUSE (P54763) Ephrin type-B receptor 2 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EPH-3) (Neural kinase) (Nuk receptor tyrosine kinase) (SEK-3) Length = 994 Score = 40.0 bits (92), Expect = 0.005 Identities = 24/91 (26%), Positives = 46/91 (50%), Gaps = 1/91 (1%) Frame = +1 Query: 325 VAVKKLLNNLGQAEK-EFRVEVEAIGHVRHKNLVRLLGYCVEGTQRILVYEYVNNGNLEQ 501 VA+K L + + ++ +F E +G H N++ L G + T +++ E++ NG+L+ Sbjct: 658 VAIKTLKSGYTEKQRRDFLSEASIMGQFDHPNVIHLEGVVTKSTPVMIITEFMENGSLDS 717 Query: 502 WLHGAMSHRGSLTWEARIKILLGTAKALAYL 594 +L + G T + +L G A + YL Sbjct: 718 FLR---QNDGQFTVIQLVGMLRGIAAGMKYL 745
>GUC2C_RAT (P23897) Heat-stable enterotoxin receptor precursor (GC-C)| (Intestinal guanylate cyclase) (EC 4.6.1.2) (STA receptor) Length = 1072 Score = 40.0 bits (92), Expect = 0.005 Identities = 25/95 (26%), Positives = 47/95 (49%), Gaps = 2/95 (2%) Frame = +1 Query: 325 VAVKKLLNNLGQAEKEFRVEVEAIGHVRHKNLVRLLGYCVEGTQRILVYEYVNNGNLEQW 504 V +K L + G ++ ++E+ + + NL + G T+ V EY G+L + Sbjct: 512 VILKDLKHCDGNFSEKQKIELNKLLQSDYYNLTKFYGTVKLDTRIFGVVEYCERGSLREV 571 Query: 505 LHGAMSHRGS--LTWEARIKILLGTAKALAYLHEA 603 L+ +S+ + WE +I +L AK ++YLH + Sbjct: 572 LNDTISYPDGTFMDWEFKISVLNDIAKGMSYLHSS 606
>EPHB1_RAT (P09759) Ephrin type-B receptor 1 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EPH-2) (ELK) Length = 984 Score = 40.0 bits (92), Expect = 0.005 Identities = 25/93 (26%), Positives = 45/93 (48%), Gaps = 1/93 (1%) Frame = +1 Query: 325 VAVKKLLNNLGQAEK-EFRVEVEAIGHVRHKNLVRLLGYCVEGTQRILVYEYVNNGNLEQ 501 VA+K L + ++ +F E +G H N++RL G + +++ E++ NG L+ Sbjct: 648 VAIKTLKAGYSEKQRRDFLSEASIMGQFDHPNIIRLEGVVTKSRPVMIITEFMENGALDS 707 Query: 502 WLHGAMSHRGSLTWEARIKILLGTAKALAYLHE 600 +L + G T + +L G A + YL E Sbjct: 708 FLR---QNDGQFTVIQLVGMLRGIAAGMKYLSE 737
>RIPK2_HUMAN (O43353) Receptor-interacting serine/threonine-protein kinase 2 (EC| 2.7.11.1) (RIP-like-interacting CLARP kinase) (Receptor-interacting protein 2) (RIP-2) (CARD-containing interleukin-1 beta-converting enzyme-associated kinase) (CARD-containi Length = 540 Score = 40.0 bits (92), Expect = 0.005 Identities = 30/94 (31%), Positives = 44/94 (46%), Gaps = 3/94 (3%) Frame = +1 Query: 325 VAVKKLLNN---LGQAEKEFRVEVEAIGHVRHKNLVRLLGYCVEGTQRILVYEYVNNGNL 495 VAVK L + L K+ E E + R ++ +LG C E +V EY+ NG+L Sbjct: 44 VAVKHLHIHTPLLDSERKDVLREAEILHKARFSYILPILGICNEPEFLGIVTEYMPNGSL 103 Query: 496 EQWLHGAMSHRGSLTWEARIKILLGTAKALAYLH 597 + LH + + W R +IL A + YLH Sbjct: 104 NELLHRKTEY-PDVAWPLRFRILHEIALGVNYLH 136
>EPHB1_HUMAN (P54762) Ephrin type-B receptor 1 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EPH-2) (NET) (HEK6) (ELK) Length = 984 Score = 39.7 bits (91), Expect = 0.007 Identities = 25/93 (26%), Positives = 45/93 (48%), Gaps = 1/93 (1%) Frame = +1 Query: 325 VAVKKLLNNLGQAEK-EFRVEVEAIGHVRHKNLVRLLGYCVEGTQRILVYEYVNNGNLEQ 501 VA+K L + ++ +F E +G H N++RL G + +++ E++ NG L+ Sbjct: 648 VAIKTLKAGYSEKQRRDFLSEASIMGQFDHPNIIRLEGVVTKSRPVMIITEFMENGALDS 707 Query: 502 WLHGAMSHRGSLTWEARIKILLGTAKALAYLHE 600 +L + G T + +L G A + YL E Sbjct: 708 FLR---QNDGQFTVIQLVGMLRGIAAGMKYLAE 737
>EPHB1_CHICK (Q07494) Ephrin type-B receptor 1 (EC 2.7.10.1) (Tyrosine-protein| kinase receptor EPH-2) (Tyrosine kinase CEK6 receptor) (Fragment) Length = 984 Score = 39.7 bits (91), Expect = 0.007 Identities = 25/93 (26%), Positives = 45/93 (48%), Gaps = 1/93 (1%) Frame = +1 Query: 325 VAVKKLLNNLGQAEK-EFRVEVEAIGHVRHKNLVRLLGYCVEGTQRILVYEYVNNGNLEQ 501 VA+K L + ++ +F E +G H N++RL G + +++ E++ NG L+ Sbjct: 648 VAIKTLKAGYSEKQRRDFLSEASIMGQFDHPNIIRLEGVVTKSRPVMIITEFMENGALDS 707 Query: 502 WLHGAMSHRGSLTWEARIKILLGTAKALAYLHE 600 +L + G T + +L G A + YL E Sbjct: 708 FLR---QNDGQFTVIQLVGMLRGIAAGMKYLAE 737
>MUSK_RAT (Q62838) Muscle, skeletal receptor tyrosine protein kinase| precursor (EC 2.7.10.1) (Muscle-specific kinase receptor) (MuSK) Length = 868 Score = 39.7 bits (91), Expect = 0.007 Identities = 22/70 (31%), Positives = 35/70 (50%), Gaps = 1/70 (1%) Frame = +1 Query: 319 TPVAVKKLLNNLG-QAEKEFRVEVEAIGHVRHKNLVRLLGYCVEGTQRILVYEYVNNGNL 495 T VAVK L + +F+ E + + N+V+LLG C G L++EY+ G+L Sbjct: 603 TMVAVKMLKEEASADMQADFQREAALMAEFDNPNIVKLLGVCAVGKPMCLLFEYMAYGDL 662 Query: 496 EQWLHGAMSH 525 ++L H Sbjct: 663 NEFLRSMSPH 672
>MUSK_MOUSE (Q61006) Muscle, skeletal receptor tyrosine protein kinase| precursor (EC 2.7.10.1) (Muscle-specific kinase receptor) (MuSK) Length = 868 Score = 39.7 bits (91), Expect = 0.007 Identities = 22/70 (31%), Positives = 35/70 (50%), Gaps = 1/70 (1%) Frame = +1 Query: 319 TPVAVKKLLNNLG-QAEKEFRVEVEAIGHVRHKNLVRLLGYCVEGTQRILVYEYVNNGNL 495 T VAVK L + +F+ E + + N+V+LLG C G L++EY+ G+L Sbjct: 603 TMVAVKMLKEEASADMQADFQREAALMAEFDNPNIVKLLGVCAVGKPMCLLFEYMAYGDL 662 Query: 496 EQWLHGAMSH 525 ++L H Sbjct: 663 NEFLRSMSPH 672
>SRMS_MOUSE (Q62270) Tyrosine-protein kinase Srms (EC 2.7.10.2) (PTK70)| Length = 496 Score = 39.7 bits (91), Expect = 0.007 Identities = 27/93 (29%), Positives = 46/93 (49%) Frame = +1 Query: 322 PVAVKKLLNNLGQAEKEFRVEVEAIGHVRHKNLVRLLGYCVEGTQRILVYEYVNNGNLEQ 501 PVAVK ++ + + E+EA+ +RH+ L+RL C G +V E + GNL+ Sbjct: 258 PVAVK-VIKSADMKLADLTKEIEALKSLRHERLIRLHAICSLGEPVYIVTELMGKGNLQV 316 Query: 502 WLHGAMSHRGSLTWEARIKILLGTAKALAYLHE 600 +L S +L+ + A+ ++YL E Sbjct: 317 YL--GSSEGKALSLPHLLGFACQVAEGMSYLEE 347
>EPHB3_XENLA (Q91735) Ephrin type-B receptor 3 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor TCK) Length = 974 Score = 39.7 bits (91), Expect = 0.007 Identities = 27/93 (29%), Positives = 43/93 (46%), Gaps = 1/93 (1%) Frame = +1 Query: 325 VAVKKL-LNNLGQAEKEFRVEVEAIGHVRHKNLVRLLGYCVEGTQRILVYEYVNNGNLEQ 501 VA+K L Q ++F E +G H N++RL G +++ E++ NG L+ Sbjct: 638 VAIKTLKAGYTEQQRRDFLGEASIMGQFDHPNIIRLEGVVTRSRPVMILTEFMENGALDS 697 Query: 502 WLHGAMSHRGSLTWEARIKILLGTAKALAYLHE 600 +L + G T + IL G A + YL E Sbjct: 698 FLR---MNDGQFTVIQLVGILRGIASGMKYLSE 727
>ZYG1_CAEBR (Q621J7) Probable serine/threonine-protein kinase zyg-1 (EC| 2.7.11.1) (Zygote defective protein 1) Length = 709 Score = 39.7 bits (91), Expect = 0.007 Identities = 26/96 (27%), Positives = 45/96 (46%) Frame = +1 Query: 313 NGTPVAVKKLLNNLGQAEKEFRVEVEAIGHVRHKNLVRLLGYCVEGTQRILVYEYVNNGN 492 NG VA+KK+ N Q + E++ + +RH+N+V+ E + LV E G+ Sbjct: 34 NGEKVAIKKIGNAASQTR--IKEEIKTMKLLRHRNIVQFYETFFENGETYLVMELCEGGS 91 Query: 493 LEQWLHGAMSHRGSLTWEARIKILLGTAKALAYLHE 600 L + + +G L + IL A+ Y+H+ Sbjct: 92 LMDY----VKQKGPLDDSTAVHILRQLIAAVKYIHD 123
>FGFR1_XENLA (P22182) Fibroblast growth factor receptor 1 precursor (EC| 2.7.10.1) (FGFR-1) Length = 812 Score = 39.7 bits (91), Expect = 0.007 Identities = 21/65 (32%), Positives = 38/65 (58%), Gaps = 2/65 (3%) Frame = +1 Query: 319 TPVAVKKLLNNLGQAE-KEFRVEVEAIGHV-RHKNLVRLLGYCVEGTQRILVYEYVNNGN 492 T VAVK L ++ + + + E+E + + +HKN++ LLG C + ++ EY + GN Sbjct: 503 TKVAVKMLKSDASEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYTSKGN 562 Query: 493 LEQWL 507 L ++L Sbjct: 563 LREYL 567
>MUSK_HUMAN (O15146) Muscle, skeletal receptor tyrosine protein kinase| precursor (EC 2.7.10.1) (Muscle-specific tyrosine protein kinase receptor) (Muscle-specific kinase receptor) (MuSK) Length = 869 Score = 39.7 bits (91), Expect = 0.007 Identities = 22/70 (31%), Positives = 35/70 (50%), Gaps = 1/70 (1%) Frame = +1 Query: 319 TPVAVKKLLNNLG-QAEKEFRVEVEAIGHVRHKNLVRLLGYCVEGTQRILVYEYVNNGNL 495 T VAVK L + +F+ E + + N+V+LLG C G L++EY+ G+L Sbjct: 604 TMVAVKMLKEEASADMQADFQREAALMAEFDNPNIVKLLGVCAVGKPMCLLFEYMAYGDL 663 Query: 496 EQWLHGAMSH 525 ++L H Sbjct: 664 NEFLRSMSPH 673
>FGFR4_MOUSE (Q03142) Fibroblast growth factor receptor 4 precursor (EC| 2.7.10.1) (FGFR-4) (Protein-tyrosine kinase receptor MPK-11) Length = 799 Score = 39.7 bits (91), Expect = 0.007 Identities = 30/104 (28%), Positives = 47/104 (45%), Gaps = 14/104 (13%) Frame = +1 Query: 325 VAVKKLLNNLGQAEKEFRV-EVEAIGHV-RHKNLVRLLGYCVEGTQRILVYEYVNNGNLE 498 VAVK L +N + V E+E + + RHKN++ LLG C + ++ E GNL Sbjct: 497 VAVKMLKDNASDKDLADLVSEMEVMKLIGRHKNIINLLGVCTQEGPLYVIVECAAKGNLR 556 Query: 499 QWLH------------GAMSHRGSLTWEARIKILLGTAKALAYL 594 ++L G S G L++ A + A+ + YL Sbjct: 557 EFLRARRPPGPDLSPDGPRSSEGPLSFPALVSCAYQVARGMQYL 600
>ABL1_MOUSE (P00520) Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2)| (p150) (c-ABL) (Abelson murine leukemia viral oncogene homolog 1) Length = 1123 Score = 39.3 bits (90), Expect = 0.009 Identities = 22/61 (36%), Positives = 33/61 (54%) Frame = +1 Query: 325 VAVKKLLNNLGQAEKEFRVEVEAIGHVRHKNLVRLLGYCVEGTQRILVYEYVNNGNLEQW 504 VAVK L + + E EF E + ++H NLV+LLG C ++ E++ GNL + Sbjct: 268 VAVKTLKEDTMEVE-EFLKEAAVMKEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDY 326 Query: 505 L 507 L Sbjct: 327 L 327
>ERBB3_PONPY (Q5RB22) Receptor tyrosine-protein kinase erbB-3 precursor (EC| 2.7.10.1) Length = 1342 Score = 39.3 bits (90), Expect = 0.009 Identities = 31/94 (32%), Positives = 49/94 (52%), Gaps = 1/94 (1%) Frame = +1 Query: 322 PVAVKKLLNNLG-QAEKEFRVEVEAIGHVRHKNLVRLLGYCVEGTQRILVYEYVNNGNLE 498 PV +K + + G Q+ + + AIG + H ++VRLLG C G+ LV +Y+ G+L Sbjct: 738 PVCIKVIEDKSGRQSFQAVTDHMLAIGSLDHAHIVRLLGLC-PGSSLQLVTQYLPLGSL- 795 Query: 499 QWLHGAMSHRGSLTWEARIKILLGTAKALAYLHE 600 L HRG+L + + + AK + YL E Sbjct: 796 --LDHVRQHRGALGPQLLLNWGVQIAKGMYYLEE 827
>ERBB3_HUMAN (P21860) Receptor tyrosine-protein kinase erbB-3 precursor (EC| 2.7.10.1) (c-erbB3) (Tyrosine kinase-type cell surface receptor HER3) Length = 1342 Score = 39.3 bits (90), Expect = 0.009 Identities = 31/94 (32%), Positives = 49/94 (52%), Gaps = 1/94 (1%) Frame = +1 Query: 322 PVAVKKLLNNLG-QAEKEFRVEVEAIGHVRHKNLVRLLGYCVEGTQRILVYEYVNNGNLE 498 PV +K + + G Q+ + + AIG + H ++VRLLG C G+ LV +Y+ G+L Sbjct: 738 PVCIKVIEDKSGRQSFQAVTDHMLAIGSLDHAHIVRLLGLC-PGSSLQLVTQYLPLGSL- 795 Query: 499 QWLHGAMSHRGSLTWEARIKILLGTAKALAYLHE 600 L HRG+L + + + AK + YL E Sbjct: 796 --LDHVRQHRGALGPQLLLNWGVQIAKGMYYLEE 827
>ABL1_HUMAN (P00519) Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2)| (p150) (c-ABL) (Abelson murine leukemia viral oncogene homolog 1) Length = 1130 Score = 39.3 bits (90), Expect = 0.009 Identities = 22/61 (36%), Positives = 33/61 (54%) Frame = +1 Query: 325 VAVKKLLNNLGQAEKEFRVEVEAIGHVRHKNLVRLLGYCVEGTQRILVYEYVNNGNLEQW 504 VAVK L + + E EF E + ++H NLV+LLG C ++ E++ GNL + Sbjct: 268 VAVKTLKEDTMEVE-EFLKEAAVMKEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDY 326 Query: 505 L 507 L Sbjct: 327 L 327
>ABL_FSVHY (P10447) Tyrosine-protein kinase transforming protein Abl (EC| 2.7.10.2) (V-abl) Length = 439 Score = 39.3 bits (90), Expect = 0.009 Identities = 22/61 (36%), Positives = 33/61 (54%) Frame = +1 Query: 325 VAVKKLLNNLGQAEKEFRVEVEAIGHVRHKNLVRLLGYCVEGTQRILVYEYVNNGNLEQW 504 VAVK L + + E EF E + ++H NLV+LLG C ++ E++ GNL + Sbjct: 217 VAVKTLKEDTMEVE-EFLKEAAVMKEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDY 275 Query: 505 L 507 L Sbjct: 276 L 276
>STK6_HUMAN (O14965) Serine/threonine-protein kinase 6 (EC 2.7.11.1)| (Serine/threonine kinase 15) (Aurora/IPL1-related kinase 1) (Aurora-related kinase 1) (hARK1) (Aurora-A) (Breast-tumor-amplified kinase) Length = 403 Score = 39.3 bits (90), Expect = 0.009 Identities = 27/91 (29%), Positives = 40/91 (43%) Frame = +1 Query: 325 VAVKKLLNNLGQAEKEFRVEVEAIGHVRHKNLVRLLGYCVEGTQRILVYEYVNNGNLEQW 504 V K L G E + R EVE H+RH N++RL GY + T+ L+ EY G Sbjct: 163 VLFKAQLEKAG-VEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGT---- 217 Query: 505 LHGAMSHRGSLTWEARIKILLGTAKALAYLH 597 ++ + + + A AL+Y H Sbjct: 218 VYRELQKLSKFDEQRTATYITELANALSYCH 248
>LRRK2_MOUSE (Q5S006) Leucine-rich repeat serine/threonine-protein kinase 2 (EC| 2.7.11.1) Length = 2527 Score = 39.3 bits (90), Expect = 0.009 Identities = 31/97 (31%), Positives = 49/97 (50%) Frame = +1 Query: 316 GTPVAVKKLLNNLGQAEKEFRVEVEAIGHVRHKNLVRLLGYCVEGTQRILVYEYVNNGNL 495 G VAVK + N + + R E+ + H+ H +L+ LL + R+LV E + G+L Sbjct: 1900 GEEVAVK--IFNKHTSLRLLRQELVVLCHLHHPSLISLLAAGIR--PRMLVMELASKGSL 1955 Query: 496 EQWLHGAMSHRGSLTWEARIKILLGTAKALAYLHEAI 606 ++ L + SLT + +I L A L YLH A+ Sbjct: 1956 DRLLQ---QDKASLTRTLQHRIALHVADGLRYLHSAM 1989
>LRRK2_HUMAN (Q5S007) Leucine-rich repeat serine/threonine-protein kinase 2 (EC| 2.7.11.1) (Dardarin) Length = 2527 Score = 39.3 bits (90), Expect = 0.009 Identities = 31/97 (31%), Positives = 49/97 (50%) Frame = +1 Query: 316 GTPVAVKKLLNNLGQAEKEFRVEVEAIGHVRHKNLVRLLGYCVEGTQRILVYEYVNNGNL 495 G VAVK + N + + R E+ + H+ H +L+ LL + R+LV E + G+L Sbjct: 1900 GEEVAVK--IFNKHTSLRLLRQELVVLCHLHHPSLISLLAAGIR--PRMLVMELASKGSL 1955 Query: 496 EQWLHGAMSHRGSLTWEARIKILLGTAKALAYLHEAI 606 ++ L + SLT + +I L A L YLH A+ Sbjct: 1956 DRLLQ---QDKASLTRTLQHRIALHVADGLRYLHSAM 1989
>ABL_MLVAB (P00521) Tyrosine-protein kinase transforming protein Abl (EC| 2.7.10.2) (V-abl) Length = 746 Score = 39.3 bits (90), Expect = 0.009 Identities = 22/61 (36%), Positives = 33/61 (54%) Frame = +1 Query: 325 VAVKKLLNNLGQAEKEFRVEVEAIGHVRHKNLVRLLGYCVEGTQRILVYEYVNNGNLEQW 504 VAVK L + + E EF E + ++H NLV+LLG C ++ E++ GNL + Sbjct: 154 VAVKTLKEDTMEVE-EFLKEAAVMKEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDY 212 Query: 505 L 507 L Sbjct: 213 L 213
>RIPK2_MOUSE (P58801) Receptor-interacting serine/threonine-protein kinase 2 (EC| 2.7.11.1) Length = 539 Score = 38.9 bits (89), Expect = 0.012 Identities = 23/72 (31%), Positives = 35/72 (48%) Frame = +1 Query: 382 EVEAIGHVRHKNLVRLLGYCVEGTQRILVYEYVNNGNLEQWLHGAMSHRGSLTWEARIKI 561 E E + R ++ +LG C E +V EY+ NG+L + LH + + W R +I Sbjct: 66 EAEILHKARFSYILPILGICNEPEFLGIVTEYMPNGSLNELLHRKTEY-PDIAWPLRFRI 124 Query: 562 LLGTAKALAYLH 597 L A + YLH Sbjct: 125 LHEIALGVNYLH 136
>STK6L_XENLA (Q91819) Serine/threonine-protein kinase Eg2-like (EC 2.7.11.1)| (p46XlEg22) Length = 408 Score = 38.9 bits (89), Expect = 0.012 Identities = 21/57 (36%), Positives = 30/57 (52%) Frame = +1 Query: 325 VAVKKLLNNLGQAEKEFRVEVEAIGHVRHKNLVRLLGYCVEGTQRILVYEYVNNGNL 495 V K L G E + R EVE H+RH N++RL GY + ++ L+ +Y G L Sbjct: 170 VLFKSQLEKAG-VEHQLRREVEIQSHLRHPNILRLYGYFHDASRVYLILDYAPGGEL 225
>PGFRB_RAT (Q05030) Beta platelet-derived growth factor receptor precursor (EC| 2.7.10.1) (PDGF-R-beta) Length = 1097 Score = 38.9 bits (89), Expect = 0.012 Identities = 23/64 (35%), Positives = 37/64 (57%), Gaps = 2/64 (3%) Frame = +1 Query: 325 VAVKKLLNNLGQAEKEFRV-EVEAIGHVR-HKNLVRLLGYCVEGTQRILVYEYVNNGNLE 498 VAVK L + +EK+ + E++ + H+ H N+V LLG C +G ++ EY G+L Sbjct: 630 VAVKMLKSTARSSEKQALMSELKIMSHLGPHLNVVNLLGACTKGGPIYIITEYCRYGDLV 689 Query: 499 QWLH 510 +LH Sbjct: 690 DYLH 693
>PGFRB_MOUSE (P05622) Beta platelet-derived growth factor receptor precursor (EC| 2.7.10.1) (PDGF-R-beta) Length = 1098 Score = 38.9 bits (89), Expect = 0.012 Identities = 23/64 (35%), Positives = 37/64 (57%), Gaps = 2/64 (3%) Frame = +1 Query: 325 VAVKKLLNNLGQAEKEFRV-EVEAIGHVR-HKNLVRLLGYCVEGTQRILVYEYVNNGNLE 498 VAVK L + +EK+ + E++ + H+ H N+V LLG C +G ++ EY G+L Sbjct: 630 VAVKMLKSTARSSEKQALMSELKIMSHLGPHLNVVNLLGACTKGGPIYIITEYCRYGDLV 689 Query: 499 QWLH 510 +LH Sbjct: 690 DYLH 693
>FGFR1_RAT (Q04589) Basic fibroblast growth factor receptor 1 precursor (EC| 2.7.10.1) (FGFR-1) (bFGF-R) (MFR) Length = 822 Score = 38.9 bits (89), Expect = 0.012 Identities = 21/65 (32%), Positives = 38/65 (58%), Gaps = 2/65 (3%) Frame = +1 Query: 319 TPVAVKKLLNNLGQAE-KEFRVEVEAIGHV-RHKNLVRLLGYCVEGTQRILVYEYVNNGN 492 T VAVK L ++ + + + E+E + + +HKN++ LLG C + ++ EY + GN Sbjct: 509 TKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGN 568 Query: 493 LEQWL 507 L ++L Sbjct: 569 LREYL 573
>FGFR1_MOUSE (P16092) Basic fibroblast growth factor receptor 1 precursor (EC| 2.7.10.1) (FGFR-1) (bFGF-R) (MFR) Length = 822 Score = 38.9 bits (89), Expect = 0.012 Identities = 21/65 (32%), Positives = 38/65 (58%), Gaps = 2/65 (3%) Frame = +1 Query: 319 TPVAVKKLLNNLGQAE-KEFRVEVEAIGHV-RHKNLVRLLGYCVEGTQRILVYEYVNNGN 492 T VAVK L ++ + + + E+E + + +HKN++ LLG C + ++ EY + GN Sbjct: 509 TKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGN 568 Query: 493 LEQWL 507 L ++L Sbjct: 569 LREYL 573
>FGFR1_HUMAN (P11362) Basic fibroblast growth factor receptor 1 precursor (EC| 2.7.10.1) (FGFR-1) (bFGF-R) (Fms-like tyrosine kinase 2) (c-fgr) (CD331 antigen) Length = 822 Score = 38.9 bits (89), Expect = 0.012 Identities = 21/65 (32%), Positives = 38/65 (58%), Gaps = 2/65 (3%) Frame = +1 Query: 319 TPVAVKKLLNNLGQAE-KEFRVEVEAIGHV-RHKNLVRLLGYCVEGTQRILVYEYVNNGN 492 T VAVK L ++ + + + E+E + + +HKN++ LLG C + ++ EY + GN Sbjct: 509 TKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGN 568 Query: 493 LEQWL 507 L ++L Sbjct: 569 LREYL 573
>RET_MOUSE (P35546) Proto-oncogene tyrosine-protein kinase receptor ret| precursor (EC 2.7.10.1) (C-ret) Length = 1115 Score = 38.9 bits (89), Expect = 0.012 Identities = 21/64 (32%), Positives = 34/64 (53%), Gaps = 1/64 (1%) Frame = +1 Query: 319 TPVAVKKLLNNLGQAE-KEFRVEVEAIGHVRHKNLVRLLGYCVEGTQRILVYEYVNNGNL 495 T VAVK L N Q+E ++ E + V H ++++L G C + +L+ EY G+L Sbjct: 754 TTVAVKMLKENASQSELRDLLSEFNLLKQVNHPHVIKLYGACSQDGPLLLIVEYAKYGSL 813 Query: 496 EQWL 507 +L Sbjct: 814 RGFL 817
>M3K1_HUMAN (Q13233) Mitogen-activated protein kinase kinase kinase 1 (EC| 2.7.11.25) (MAPK/ERK kinase kinase 1) (MEK kinase 1) (MEKK 1) (Fragment) Length = 1495 Score = 38.9 bits (89), Expect = 0.012 Identities = 28/101 (27%), Positives = 51/101 (50%), Gaps = 6/101 (5%) Frame = +1 Query: 316 GTPVAVKKL--LNNLGQAEKE----FRVEVEAIGHVRHKNLVRLLGYCVEGTQRILVYEY 477 GT +AVK++ + N ++E R E+ + H+ H N++R+LG E + L E+ Sbjct: 1249 GTLMAVKQVTYVRNTSSEQEEVVEALREEIRMMSHLNHPNIIRMLGATCEKSNYNLFIEW 1308 Query: 478 VNNGNLEQWLHGAMSHRGSLTWEARIKILLGTAKALAYLHE 600 + G++ L + + S+ ++L G L+YLHE Sbjct: 1309 MAGGSVAHLLSKYGAFKESVVINYTEQLLRG----LSYLHE 1345
>DDR2_HUMAN (Q16832) Discoidin domain-containing receptor 2 precursor (EC| 2.7.10.1) (Discoidin domain receptor 2) (Receptor protein-tyrosine kinase TKT) (Tyrosine-protein kinase TYRO 10) (Neurotrophic tyrosine kinase, receptor-related 3) (CD167b antigen) Length = 855 Score = 38.9 bits (89), Expect = 0.012 Identities = 19/62 (30%), Positives = 35/62 (56%), Gaps = 1/62 (1%) Frame = +1 Query: 325 VAVKKLLNNLGQ-AEKEFRVEVEAIGHVRHKNLVRLLGYCVEGTQRILVYEYVNNGNLEQ 501 VAVK L + + A +F E++ + ++ N++ LL C+ ++ EY+ NG+L Q Sbjct: 605 VAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLSVCITDDPLCMITEYMENGDLNQ 664 Query: 502 WL 507 +L Sbjct: 665 FL 666
>PGFRB_HUMAN (P09619) Beta platelet-derived growth factor receptor precursor (EC| 2.7.10.1) (PDGF-R-beta) (CD140b antigen) Length = 1106 Score = 38.9 bits (89), Expect = 0.012 Identities = 23/64 (35%), Positives = 37/64 (57%), Gaps = 2/64 (3%) Frame = +1 Query: 325 VAVKKLLNNLGQAEKEFRV-EVEAIGHVR-HKNLVRLLGYCVEGTQRILVYEYVNNGNLE 498 VAVK L + +EK+ + E++ + H+ H N+V LLG C +G ++ EY G+L Sbjct: 631 VAVKMLKSTARSSEKQALMSELKIMSHLGPHLNVVNLLGACTKGGPIYIITEYCRYGDLV 690 Query: 499 QWLH 510 +LH Sbjct: 691 DYLH 694
>ROR1_HUMAN (Q01973) Tyrosine-protein kinase transmembrane receptor ROR1| precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase, receptor-related 1) Length = 937 Score = 38.9 bits (89), Expect = 0.012 Identities = 21/62 (33%), Positives = 35/62 (56%), Gaps = 1/62 (1%) Frame = +1 Query: 325 VAVKKLLN-NLGQAEKEFRVEVEAIGHVRHKNLVRLLGYCVEGTQRILVYEYVNNGNLEQ 501 VA+K L + N Q EF+ E + + H N+V LLG + +++EY+N G+L + Sbjct: 503 VAIKTLKDYNNPQQWMEFQQEASLMAELHHPNIVCLLGAVTQEQPVCMLFEYINQGDLHE 562 Query: 502 WL 507 +L Sbjct: 563 FL 564
>STK6_XENLA (Q91820) Serine/threonine-protein kinase Eg2 (EC 2.7.11.1) (pEg2)| (p46Eg265) Length = 407 Score = 38.9 bits (89), Expect = 0.012 Identities = 21/57 (36%), Positives = 30/57 (52%) Frame = +1 Query: 325 VAVKKLLNNLGQAEKEFRVEVEAIGHVRHKNLVRLLGYCVEGTQRILVYEYVNNGNL 495 V K L G E + R EVE H+RH N++RL GY + ++ L+ +Y G L Sbjct: 170 VLFKSQLEKAG-VEHQLRREVEIQSHLRHPNILRLYGYFHDASRVYLILDYAPGGEL 225
>PGFRB_CANFA (Q6QNF3) Beta platelet-derived growth factor receptor precursor (EC| 2.7.10.1) (PDGF-R-beta) Length = 1103 Score = 38.9 bits (89), Expect = 0.012 Identities = 23/64 (35%), Positives = 37/64 (57%), Gaps = 2/64 (3%) Frame = +1 Query: 325 VAVKKLLNNLGQAEKEFRV-EVEAIGHVR-HKNLVRLLGYCVEGTQRILVYEYVNNGNLE 498 VAVK L + +EK+ + E++ + H+ H N+V LLG C +G ++ EY G+L Sbjct: 631 VAVKMLKSTARSSEKQALMSELKIMSHLGPHLNVVNLLGACTKGGPIYIITEYCRYGDLV 690 Query: 499 QWLH 510 +LH Sbjct: 691 DYLH 694
>FGFR1_CHICK (P21804) Basic fibroblast growth factor receptor 1 precursor (EC| 2.7.10.1) Length = 819 Score = 38.9 bits (89), Expect = 0.012 Identities = 21/65 (32%), Positives = 38/65 (58%), Gaps = 2/65 (3%) Frame = +1 Query: 319 TPVAVKKLLNNLGQAE-KEFRVEVEAIGHV-RHKNLVRLLGYCVEGTQRILVYEYVNNGN 492 T VAVK L ++ + + + E+E + + +HKN++ LLG C + ++ EY + GN Sbjct: 507 TKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGN 566 Query: 493 LEQWL 507 L ++L Sbjct: 567 LREYL 571
>STK6_MOUSE (P97477) Serine/threonine-protein kinase 6 (EC 2.7.11.1)| (Aurora-family kinase 1) (Aurora/IPL1-related kinase 1) (Ipl1- and aurora-related kinase 1) (Aurora-A) (Serine/threonine-protein kinase Ayk1) Length = 395 Score = 38.9 bits (89), Expect = 0.012 Identities = 23/78 (29%), Positives = 36/78 (46%) Frame = +1 Query: 364 EKEFRVEVEAIGHVRHKNLVRLLGYCVEGTQRILVYEYVNNGNLEQWLHGAMSHRGSLTW 543 E + R EVE H+RH N++RL GY + T+ L+ EY G ++ + Sbjct: 166 EHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGT----VYRELQKLSKFDE 221 Query: 544 EARIKILLGTAKALAYLH 597 + + A AL+Y H Sbjct: 222 QRTATYITELANALSYCH 239
>STK6_RAT (P59241) Serine/threonine-protein kinase 6 (EC 2.7.11.1) (Aurora-A)| (ratAurA) Length = 397 Score = 38.9 bits (89), Expect = 0.012 Identities = 23/78 (29%), Positives = 36/78 (46%) Frame = +1 Query: 364 EKEFRVEVEAIGHVRHKNLVRLLGYCVEGTQRILVYEYVNNGNLEQWLHGAMSHRGSLTW 543 E + R EVE H+RH N++RL GY + T+ L+ EY G ++ + Sbjct: 168 EHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGT----VYRELQKLSKFDE 223 Query: 544 EARIKILLGTAKALAYLH 597 + + A AL+Y H Sbjct: 224 QRTATYITELANALSYCH 241
>FLK_RAT (P09760) Tyrosine-protein kinase FLK (EC 2.7.10.2) (Fragment)| Length = 323 Score = 38.5 bits (88), Expect = 0.015 Identities = 26/93 (27%), Positives = 43/93 (46%), Gaps = 1/93 (1%) Frame = +1 Query: 319 TPVAVKKLLNNLGQAEK-EFRVEVEAIGHVRHKNLVRLLGYCVEGTQRILVYEYVNNGNL 495 TPVAVK +L Q K +F E + + H N+V+L+G C + ++ E V G+ Sbjct: 87 TPVAVKTCKEDLPQELKIKFLQEAKILKQYDHPNIVKLIGVCTQRQPVYIIMELVPGGDF 146 Query: 496 EQWLHGAMSHRGSLTWEARIKILLGTAKALAYL 594 +L + L + ++ L A + YL Sbjct: 147 LSFLR---KRKDELKLKQLVRFSLDVAAGMLYL 176
>EPHB2_CHICK (P28693) Ephrin type-B receptor 2 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor CEK5) Length = 1004 Score = 38.5 bits (88), Expect = 0.015 Identities = 23/91 (25%), Positives = 46/91 (50%), Gaps = 1/91 (1%) Frame = +1 Query: 325 VAVKKLLNNLGQAEK-EFRVEVEAIGHVRHKNLVRLLGYCVEGTQRILVYEYVNNGNLEQ 501 VA+K L + + ++ +F E +G H N++ L G + + +++ E++ NG+L+ Sbjct: 668 VAIKTLKSGYTEKQRRDFLSEASIMGQFDHPNVIHLEGVVTKSSPVMIITEFMENGSLDS 727 Query: 502 WLHGAMSHRGSLTWEARIKILLGTAKALAYL 594 +L + G T + +L G A + YL Sbjct: 728 FLR---QNDGQFTVIQLVGMLRGIAAGMKYL 755
>EPHB5_CHICK (Q07497) Ephrin type-B receptor 5 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase CEK9) Length = 1002 Score = 38.5 bits (88), Expect = 0.015 Identities = 24/93 (25%), Positives = 44/93 (47%), Gaps = 1/93 (1%) Frame = +1 Query: 325 VAVKKLLNNL-GQAEKEFRVEVEAIGHVRHKNLVRLLGYCVEGTQRILVYEYVNNGNLEQ 501 VA+K L + + +EF E +G H N++ L G + ++V E++ NG+L+ Sbjct: 666 VAIKTLKSGYTDEQRREFLSEASIMGQFEHPNVIHLEGVVTKSRPVMIVTEFMENGSLDS 725 Query: 502 WLHGAMSHRGSLTWEARIKILLGTAKALAYLHE 600 +L G + + +L G A + YL + Sbjct: 726 FLR---QKEGQFSVLQLVGMLRGIAAGMRYLSD 755
>EPHA2_HUMAN (P29317) Ephrin type-A receptor 2 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor ECK) (Epithelial cell kinase) Length = 976 Score = 38.5 bits (88), Expect = 0.015 Identities = 28/94 (29%), Positives = 45/94 (47%), Gaps = 3/94 (3%) Frame = +1 Query: 322 PVAVKKLLNNLGQAEKE---FRVEVEAIGHVRHKNLVRLLGYCVEGTQRILVYEYVNNGN 492 PVA+K L G EK+ F E +G H N++RL G + +++ EY+ NG Sbjct: 642 PVAIKTL--KAGYTEKQRVDFLGEAGIMGQFSHHNIIRLEGVISKYKPMMIITEYMENGA 699 Query: 493 LEQWLHGAMSHRGSLTWEARIKILLGTAKALAYL 594 L+++L G + + +L G A + YL Sbjct: 700 LDKFLR---EKDGEFSVLQLVGMLRGIAAGMKYL 730
>EPHB2_COTJA (Q90344) Ephrin type-B receptor 2 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor QEK5) Length = 987 Score = 38.5 bits (88), Expect = 0.015 Identities = 23/91 (25%), Positives = 46/91 (50%), Gaps = 1/91 (1%) Frame = +1 Query: 325 VAVKKLLNNLGQAEK-EFRVEVEAIGHVRHKNLVRLLGYCVEGTQRILVYEYVNNGNLEQ 501 VA+K L + + ++ +F E +G H N++ L G + + +++ E++ NG+L+ Sbjct: 651 VAIKTLKSGYTEKQRRDFLSEASIMGQFDHPNVIHLEGVVTKSSPVMIITEFMENGSLDS 710 Query: 502 WLHGAMSHRGSLTWEARIKILLGTAKALAYL 594 +L + G T + +L G A + YL Sbjct: 711 FLR---QNDGQFTVIQLVGMLRGIAAGMKYL 738
>GCY3E_DROME (Q07553) Guanylate cyclase 32E precursor (EC 4.6.1.2)| Length = 1163 Score = 38.5 bits (88), Expect = 0.015 Identities = 24/96 (25%), Positives = 44/96 (45%) Frame = +1 Query: 316 GTPVAVKKLLNNLGQAEKEFRVEVEAIGHVRHKNLVRLLGYCVEGTQRILVYEYVNNGNL 495 G VA+KK+ + R E++ + VRH+N++ +G + I+ Y G+L Sbjct: 553 GNIVAMKKIHKKSVDITRSIRKELKLMREVRHENIINFIGASTDHGSVIIFTTYCARGSL 612 Query: 496 EQWLHGAMSHRGSLTWEARIKILLGTAKALAYLHEA 603 E L H + + + +L K + YLH++ Sbjct: 613 EDVLANEDLHLDHMFISSLVSDIL---KGMIYLHDS 645
>SPKB_SYNY3 (P74297) Serine/threonine-protein kinase B (EC 2.7.11.1)| Length = 574 Score = 38.1 bits (87), Expect = 0.020 Identities = 32/102 (31%), Positives = 44/102 (43%), Gaps = 8/102 (7%) Frame = +1 Query: 316 GTPVAVKKLL-------NNLGQAEKEFRVEVEAIGHV-RHKNLVRLLGYCVEGTQRILVY 471 GTP+ V K L N A++ F E + +G V H + RLL Y + Q LV Sbjct: 58 GTPICVVKQLRPQTDDPNVFRMAKELFEREAQTLGRVGNHPQVPRLLDYFEDDHQFYLVQ 117 Query: 472 EYVNNGNLEQWLHGAMSHRGSLTWEARIKILLGTAKALAYLH 597 EYV N LH + G+ T + + L L Y+H Sbjct: 118 EYVKGHN----LHQEVKKNGTFTEGSVKQFLTEILPILDYIH 155
>MUSK_CHICK (Q8AXY6) Muscle, skeletal receptor tyrosine protein kinase| precursor (EC 2.7.10.1) (Muscle-specific tyrosine protein kinase receptor) (Muscle-specific kinase receptor) (MuSK) Length = 947 Score = 38.1 bits (87), Expect = 0.020 Identities = 21/64 (32%), Positives = 34/64 (53%), Gaps = 1/64 (1%) Frame = +1 Query: 319 TPVAVKKLLNNLG-QAEKEFRVEVEAIGHVRHKNLVRLLGYCVEGTQRILVYEYVNNGNL 495 T VAVK L + +F+ E + + N+V+LLG C G L++EY+ G+L Sbjct: 684 TMVAVKMLKEEASADMQADFQREAALMAEFDNPNIVKLLGVCAVGKPMCLLFEYMAYGDL 743 Query: 496 EQWL 507 ++L Sbjct: 744 NEYL 747
>FGFR4_HUMAN (P22455) Fibroblast growth factor receptor 4 precursor (EC| 2.7.10.1) (FGFR-4) (CD334 antigen) Length = 802 Score = 38.1 bits (87), Expect = 0.020 Identities = 29/104 (27%), Positives = 46/104 (44%), Gaps = 14/104 (13%) Frame = +1 Query: 325 VAVKKLLNNLGQAEKEFRV-EVEAIGHV-RHKNLVRLLGYCVEGTQRILVYEYVNNGNLE 498 VAVK L +N + V E+E + + RHKN++ LLG C + ++ E GNL Sbjct: 500 VAVKMLKDNASDKDLADLVSEMEVMKLIGRHKNIINLLGVCTQEGPLYVIVECAAKGNLR 559 Query: 499 QWLH------------GAMSHRGSLTWEARIKILLGTAKALAYL 594 ++L G S G L++ + A+ + YL Sbjct: 560 EFLRARRPPGPDLSPDGPRSSEGPLSFPVLVSCAYQVARGMQYL 603
>LIMK1_RAT (P53669) LIM domain kinase 1 (EC 2.7.11.1) (LIMK-1)| Length = 647 Score = 38.1 bits (87), Expect = 0.020 Identities = 21/94 (22%), Positives = 42/94 (44%) Frame = +1 Query: 316 GTPVAVKKLLNNLGQAEKEFRVEVEAIGHVRHKNLVRLLGYCVEGTQRILVYEYVNNGNL 495 G + +K+L+ + ++ F EV+ + + H N+++ +G + + + EY+ G L Sbjct: 362 GEVMVMKELIRFDEETQRTFLKEVKVMRCLEHPNVLKFIGVLYKDKRLNFITEYIKGGTL 421 Query: 496 EQWLHGAMSHRGSLTWEARIKILLGTAKALAYLH 597 + S W R+ A +AYLH Sbjct: 422 RGII---KSMDSQYPWSQRVSFAKDIASGMAYLH 452
>LIMK1_MOUSE (P53668) LIM domain kinase 1 (EC 2.7.11.1) (LIMK-1) (KIZ-1)| Length = 647 Score = 38.1 bits (87), Expect = 0.020 Identities = 21/94 (22%), Positives = 42/94 (44%) Frame = +1 Query: 316 GTPVAVKKLLNNLGQAEKEFRVEVEAIGHVRHKNLVRLLGYCVEGTQRILVYEYVNNGNL 495 G + +K+L+ + ++ F EV+ + + H N+++ +G + + + EY+ G L Sbjct: 362 GEVMVMKELIRFDEETQRTFLKEVKVMRCLEHPNVLKFIGVLYKDKRLNFITEYIKGGTL 421 Query: 496 EQWLHGAMSHRGSLTWEARIKILLGTAKALAYLH 597 + S W R+ A +AYLH Sbjct: 422 RGIIKNMDS---QYPWSQRVSFAKDIASGMAYLH 452
>LIMK1_HUMAN (P53667) LIM domain kinase 1 (EC 2.7.11.1) (LIMK-1)| Length = 647 Score = 38.1 bits (87), Expect = 0.020 Identities = 21/94 (22%), Positives = 42/94 (44%) Frame = +1 Query: 316 GTPVAVKKLLNNLGQAEKEFRVEVEAIGHVRHKNLVRLLGYCVEGTQRILVYEYVNNGNL 495 G + +K+L+ + ++ F EV+ + + H N+++ +G + + + EY+ G L Sbjct: 362 GEVMVMKELIRFDEETQRTFLKEVKVMRCLEHPNVLKFIGVLYKDKRLNFITEYIKGGTL 421 Query: 496 EQWLHGAMSHRGSLTWEARIKILLGTAKALAYLH 597 + S W R+ A +AYLH Sbjct: 422 RGII---KSMDSQYPWSQRVSFAKDIASGMAYLH 452
>ROR1_MOUSE (Q9Z139) Tyrosine-protein kinase transmembrane receptor ROR1| precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase, receptor-related 1) (mROR1) Length = 937 Score = 38.1 bits (87), Expect = 0.020 Identities = 21/62 (33%), Positives = 35/62 (56%), Gaps = 1/62 (1%) Frame = +1 Query: 325 VAVKKLLN-NLGQAEKEFRVEVEAIGHVRHKNLVRLLGYCVEGTQRILVYEYVNNGNLEQ 501 VA+K L + N Q EF+ E + + H N+V LLG + +++EY+N G+L + Sbjct: 503 VAIKTLKDYNNPQQWTEFQQEASLMAELHHPNIVCLLGAVTQEQPVCMLFEYMNQGDLHE 562 Query: 502 WL 507 +L Sbjct: 563 FL 564
>SRK1_SPOLA (P42686) Tyrosine-protein kinase isoform SRK1 (EC 2.7.10.2)| Length = 505 Score = 38.1 bits (87), Expect = 0.020 Identities = 25/96 (26%), Positives = 42/96 (43%) Frame = +1 Query: 313 NGTPVAVKKLLNNLGQAEKEFRVEVEAIGHVRHKNLVRLLGYCVEGTQRILVYEYVNNGN 492 NGT K L + +EF E + +RH L++L C + +V E + G+ Sbjct: 260 NGTTSVAVKTLKPGTMSVEEFLQEASIMKRLRHPKLIQLYAVCTKEEPIYIVTELMKYGS 319 Query: 493 LEQWLHGAMSHRGSLTWEARIKILLGTAKALAYLHE 600 L ++L G G L E + + A ++YL + Sbjct: 320 LLEYLRG---EDGVLKIEQLVDVAAQVASGMSYLEQ 352
>CEK3_CHICK (P18461) Tyrosine kinase receptor CEK3 precursor (EC 2.7.10.1)| Length = 823 Score = 37.4 bits (85), Expect = 0.034 Identities = 21/63 (33%), Positives = 37/63 (58%), Gaps = 2/63 (3%) Frame = +1 Query: 325 VAVKKLLNNLGQAEKEFRV-EVEAIGHV-RHKNLVRLLGYCVEGTQRILVYEYVNNGNLE 498 VAVK L ++ + + V E+E + + +HKN++ LLG C + ++ EY + GNL Sbjct: 516 VAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLR 575 Query: 499 QWL 507 ++L Sbjct: 576 EYL 578
>FGFR2_MOUSE (P21803) Fibroblast growth factor receptor 2 precursor (EC| 2.7.10.1) (FGFR-2) (Keratinocyte growth factor receptor) Length = 821 Score = 37.4 bits (85), Expect = 0.034 Identities = 21/63 (33%), Positives = 37/63 (58%), Gaps = 2/63 (3%) Frame = +1 Query: 325 VAVKKLLNNLGQAEKEFRV-EVEAIGHV-RHKNLVRLLGYCVEGTQRILVYEYVNNGNLE 498 VAVK L ++ + + V E+E + + +HKN++ LLG C + ++ EY + GNL Sbjct: 514 VAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLR 573 Query: 499 QWL 507 ++L Sbjct: 574 EYL 576
>FGFR2_HUMAN (P21802) Fibroblast growth factor receptor 2 precursor (EC| 2.7.10.1) (FGFR-2) (Keratinocyte growth factor receptor 2) (CD332 antigen) Length = 821 Score = 37.4 bits (85), Expect = 0.034 Identities = 21/63 (33%), Positives = 37/63 (58%), Gaps = 2/63 (3%) Frame = +1 Query: 325 VAVKKLLNNLGQAEKEFRV-EVEAIGHV-RHKNLVRLLGYCVEGTQRILVYEYVNNGNLE 498 VAVK L ++ + + V E+E + + +HKN++ LLG C + ++ EY + GNL Sbjct: 514 VAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLR 573 Query: 499 QWL 507 ++L Sbjct: 574 EYL 576
>EPHA2_MOUSE (Q03145) Ephrin type-A receptor 2 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor ECK) (Epithelial cell kinase) (MPK-5) (SEK-2) Length = 977 Score = 37.4 bits (85), Expect = 0.034 Identities = 27/94 (28%), Positives = 44/94 (46%), Gaps = 3/94 (3%) Frame = +1 Query: 322 PVAVKKLLNNLGQAEKE---FRVEVEAIGHVRHKNLVRLLGYCVEGTQRILVYEYVNNGN 492 PVA+K L G EK+ F E +G H N++ L G + +++ EY+ NG Sbjct: 643 PVAIKTL--KAGYTEKQRVDFLSEASIMGQFSHHNIIPLEGVVSKYKPMMIITEYMENGA 700 Query: 493 LEQWLHGAMSHRGSLTWEARIKILLGTAKALAYL 594 L+++L G + + +L G A + YL Sbjct: 701 LDKFLR---EKDGEFSVLQLVGMLRGIASGMKYL 731
>MERTK_MOUSE (Q60805) Proto-oncogene tyrosine-protein kinase MER precursor (EC| 2.7.10.1) (C-mer) (Receptor tyrosine kinase MerTK) Length = 994 Score = 37.4 bits (85), Expect = 0.034 Identities = 27/99 (27%), Positives = 52/99 (52%), Gaps = 9/99 (9%) Frame = +1 Query: 325 VAVKKL-LNNLGQAE-KEFRVEVEAIGHVRHKNLVRLLGYCVEGTQR-----ILVYEYVN 483 VAVK + L+N Q E +EF E + H N++RLLG C+E + + +++ ++ Sbjct: 611 VAVKTMKLDNFSQREIEEFLSEAACMKDFNHPNVIRLLGVCIELSSQGIPKPMVILPFMK 670 Query: 484 NGNLEQWLHGAMSHRGS--LTWEARIKILLGTAKALAYL 594 G+L +L + + G + + +K ++ A+ + YL Sbjct: 671 YGDLHTFLLYSRLNTGPKYIHLQTLLKFMMDIAQGMEYL 709
>AURKC_HUMAN (Q9UQB9) Serine/threonine-protein kinase 13 (EC 2.7.11.1)| (Aurora/Ipl1/Eg2 protein 2) (Aurora/Ipl1-related kinase 3) (Aurora-C) Length = 309 Score = 37.4 bits (85), Expect = 0.034 Identities = 29/97 (29%), Positives = 44/97 (45%), Gaps = 5/97 (5%) Frame = +1 Query: 325 VAVKKLLNNLGQAEKE-----FRVEVEAIGHVRHKNLVRLLGYCVEGTQRILVYEYVNNG 489 VA+K L + Q EKE R E+E H++H N++RL Y + + L+ EY G Sbjct: 69 VALKVLFKS--QIEKEGLEHQLRREIEIQAHLQHPNILRLYNYFHDARRVYLILEYAPRG 126 Query: 490 NLEQWLHGAMSHRGSLTWEARIKILLGTAKALAYLHE 600 L+ + L + I+ A AL Y H+ Sbjct: 127 E----LYKELQKSEKLDEQRTATIIEELADALTYCHD 159
>RET_HUMAN (P07949) Proto-oncogene tyrosine-protein kinase receptor ret| precursor (EC 2.7.10.1) (C-ret) Length = 1114 Score = 37.0 bits (84), Expect = 0.045 Identities = 20/64 (31%), Positives = 33/64 (51%), Gaps = 1/64 (1%) Frame = +1 Query: 319 TPVAVKKLLNNLGQAE-KEFRVEVEAIGHVRHKNLVRLLGYCVEGTQRILVYEYVNNGNL 495 T VAVK L N +E ++ E + V H ++++L G C + +L+ EY G+L Sbjct: 753 TTVAVKMLKENASPSELRDLLSEFNVLKQVNHPHVIKLYGACSQDGPLLLIVEYAKYGSL 812 Query: 496 EQWL 507 +L Sbjct: 813 RGFL 816
>BTK_MOUSE (P35991) Tyrosine-protein kinase BTK (EC 2.7.10.2) (Bruton's| tyrosine kinase) (Agammaglobulinaemia tyrosine kinase) (ATK) (B cell progenitor kinase) (BPK) (Kinase EMB) Length = 658 Score = 37.0 bits (84), Expect = 0.045 Identities = 20/64 (31%), Positives = 34/64 (53%) Frame = +1 Query: 337 KLLNNLGQAEKEFRVEVEAIGHVRHKNLVRLLGYCVEGTQRILVYEYVNNGNLEQWLHGA 516 K++ +E EF E + + ++ H+ LV+L G C + ++ EY+ NG L +L Sbjct: 429 KMIREGSMSEDEFIEEAKVMMNLSHEKLVQLYGVCTKQRPIFIITEYMANGCLLNYLR-E 487 Query: 517 MSHR 528 M HR Sbjct: 488 MRHR 491
>BTK_HUMAN (Q06187) Tyrosine-protein kinase BTK (EC 2.7.10.2) (Bruton's| tyrosine kinase) (Agammaglobulinaemia tyrosine kinase) (ATK) (B cell progenitor kinase) (BPK) Length = 658 Score = 37.0 bits (84), Expect = 0.045 Identities = 20/64 (31%), Positives = 34/64 (53%) Frame = +1 Query: 337 KLLNNLGQAEKEFRVEVEAIGHVRHKNLVRLLGYCVEGTQRILVYEYVNNGNLEQWLHGA 516 K++ +E EF E + + ++ H+ LV+L G C + ++ EY+ NG L +L Sbjct: 429 KMIKEGSMSEDEFIEEAKVMMNLSHEKLVQLYGVCTKQRPIFIITEYMANGCLLNYLR-E 487 Query: 517 MSHR 528 M HR Sbjct: 488 MRHR 491
>EPHB3_BRARE (O13147) Ephrin type-B receptor 3 (EC 2.7.10.1) (Tyrosine-protein| kinase receptor ZEK3) (EPH-like kinase 3) (Fragment) Length = 500 Score = 37.0 bits (84), Expect = 0.045 Identities = 25/95 (26%), Positives = 44/95 (46%), Gaps = 1/95 (1%) Frame = +1 Query: 319 TPVAVKKLLNNLGQAEK-EFRVEVEAIGHVRHKNLVRLLGYCVEGTQRILVYEYVNNGNL 495 T VA+K L + ++ +F E +G H N++ L G ++V E++ NG L Sbjct: 214 TTVAIKTLKAGYTEHQRRDFLSEASIMGQFDHPNVIHLEGVLTRSCPVLIVTEFMENGAL 273 Query: 496 EQWLHGAMSHRGSLTWEARIKILLGTAKALAYLHE 600 + +L + G T + +L G A + YL + Sbjct: 274 DSFLR---LNDGRFTVTQLVGMLRGIAAGMKYLSD 305
>FGFR3_MOUSE (Q61851) Fibroblast growth factor receptor 3 precursor (EC| 2.7.10.1) (FGFR-3) (Heparin-binding growth factor receptor) Length = 801 Score = 37.0 bits (84), Expect = 0.045 Identities = 22/63 (34%), Positives = 36/63 (57%), Gaps = 2/63 (3%) Frame = +1 Query: 325 VAVKKLLNNLGQAEKEFRV-EVEAIGHV-RHKNLVRLLGYCVEGTQRILVYEYVNNGNLE 498 VAVK L ++ + V E+E + + +HKN++ LLG C +G ++ EY GNL Sbjct: 499 VAVKMLKDDATDKDLSDLVSEMEMMKMIGKHKNIINLLGACTQGGPLYVLVEYAAKGNLR 558 Query: 499 QWL 507 ++L Sbjct: 559 EFL 561
>ANPRB_ANGJA (P55202) Atrial natriuretic peptide receptor B precursor (ANP-B)| (ANPRB) (GC-B) (Guanylate cyclase) (EC 4.6.1.2) (NPR-B) (Atrial natriuretic peptide B-type receptor) Length = 1050 Score = 37.0 bits (84), Expect = 0.045 Identities = 22/96 (22%), Positives = 45/96 (46%) Frame = +1 Query: 316 GTPVAVKKLLNNLGQAEKEFRVEVEAIGHVRHKNLVRLLGYCVEGTQRILVYEYVNNGNL 495 G VA+K + + ++ E++ + V+ +L R +G C++ +V EY G+L Sbjct: 549 GNLVAIKHVNKKRIELTRQVLFELKHMRDVQFNHLTRFIGACIDPPNICIVTEYCPRGSL 608 Query: 496 EQWLHGAMSHRGSLTWEARIKILLGTAKALAYLHEA 603 + L + +L W R ++ K + +LH + Sbjct: 609 QDILE---NESINLDWMFRYSLINDIVKGMNFLHNS 641
>FGFR3_HUMAN (P22607) Fibroblast growth factor receptor 3 precursor (EC| 2.7.10.1) (FGFR-3) (CD333 antigen) Length = 806 Score = 37.0 bits (84), Expect = 0.045 Identities = 22/63 (34%), Positives = 36/63 (57%), Gaps = 2/63 (3%) Frame = +1 Query: 325 VAVKKLLNNLGQAEKEFRV-EVEAIGHV-RHKNLVRLLGYCVEGTQRILVYEYVNNGNLE 498 VAVK L ++ + V E+E + + +HKN++ LLG C +G ++ EY GNL Sbjct: 505 VAVKMLKDDATDKDLSDLVSEMEMMKMIGKHKNIINLLGACTQGGPLYVLVEYAAKGNLR 564 Query: 499 QWL 507 ++L Sbjct: 565 EFL 567
>KFMS_FSVMD (P00545) Tyrosine-protein kinase transforming protein fms (EC| 2.7.10.1) Length = 978 Score = 36.6 bits (83), Expect = 0.059 Identities = 23/63 (36%), Positives = 37/63 (58%), Gaps = 2/63 (3%) Frame = +1 Query: 325 VAVKKLLNNLGQAEKEFRV-EVEAIGHV-RHKNLVRLLGYCVEGTQRILVYEYVNNGNLE 498 VAVK L + EKE + E++ + H+ +H+N+V LLG C G +++ EY G+L Sbjct: 644 VAVKMLKSTAHADEKEALMSELKIMSHLGQHENIVNLLGACTHGGPVLVITEYCCYGDLL 703 Query: 499 QWL 507 +L Sbjct: 704 NFL 706
>CSF1R_RAT (Q00495) Macrophage colony-stimulating factor 1 receptor precursor| (CSF-1-R) (EC 2.7.10.1) (Fms proto-oncogene) (c-fms) Length = 978 Score = 36.6 bits (83), Expect = 0.059 Identities = 23/63 (36%), Positives = 37/63 (58%), Gaps = 2/63 (3%) Frame = +1 Query: 325 VAVKKLLNNLGQAEKEFRV-EVEAIGHV-RHKNLVRLLGYCVEGTQRILVYEYVNNGNLE 498 VAVK L + EKE + E++ + H+ +H+N+V LLG C G +++ EY G+L Sbjct: 611 VAVKMLKSTAHADEKEALMSELKIMSHLGQHENIVNLLGACTHGGPVLVITEYCCYGDLL 670 Query: 499 QWL 507 +L Sbjct: 671 NFL 673
>CSF1R_HUMAN (P07333) Macrophage colony-stimulating factor 1 receptor precursor| (CSF-1-R) (EC 2.7.10.1) (Fms proto-oncogene) (c-fms) (CD115 antigen) Length = 972 Score = 36.6 bits (83), Expect = 0.059 Identities = 23/63 (36%), Positives = 37/63 (58%), Gaps = 2/63 (3%) Frame = +1 Query: 325 VAVKKLLNNLGQAEKEFRV-EVEAIGHV-RHKNLVRLLGYCVEGTQRILVYEYVNNGNLE 498 VAVK L + EKE + E++ + H+ +H+N+V LLG C G +++ EY G+L Sbjct: 613 VAVKMLKSTAHADEKEALMSELKIMSHLGQHENIVNLLGACTHGGPVLVITEYCCYGDLL 672 Query: 499 QWL 507 +L Sbjct: 673 NFL 675
>CSF1R_FELCA (P13369) Macrophage colony-stimulating factor 1 receptor precursor| (CSF-1-R) (EC 2.7.10.1) (Fms proto-oncogene) (c-fms) Length = 980 Score = 36.6 bits (83), Expect = 0.059 Identities = 23/63 (36%), Positives = 37/63 (58%), Gaps = 2/63 (3%) Frame = +1 Query: 325 VAVKKLLNNLGQAEKEFRV-EVEAIGHV-RHKNLVRLLGYCVEGTQRILVYEYVNNGNLE 498 VAVK L + EKE + E++ + H+ +H+N+V LLG C G +++ EY G+L Sbjct: 610 VAVKMLKSTAHADEKEALMSELKIMSHLGQHENIVNLLGACTHGGPVLVITEYCCYGDLL 669 Query: 499 QWL 507 +L Sbjct: 670 NFL 672
>FER_HUMAN (P16591) Proto-oncogene tyrosine-protein kinase FER (EC 2.7.10.2)| (p94-FER) (c-FER) Length = 822 Score = 36.6 bits (83), Expect = 0.059 Identities = 26/93 (27%), Positives = 43/93 (46%), Gaps = 1/93 (1%) Frame = +1 Query: 319 TPVAVKKLLNNLGQAEK-EFRVEVEAIGHVRHKNLVRLLGYCVEGTQRILVYEYVNNGNL 495 T VAVK +L Q K +F E + + H N+V+L+G C + ++ E V+ G+ Sbjct: 586 TSVAVKTCKEDLPQELKIKFLQEAKILKQYDHPNIVKLIGVCTQRQPVYIIMELVSGGDF 645 Query: 496 EQWLHGAMSHRGSLTWEARIKILLGTAKALAYL 594 +L + L + +K L A + YL Sbjct: 646 LTFLR---RKKDELKLKQLVKFSLDAAAGMLYL 675
>EPA4A_XENLA (Q91845) Ephrin type-A receptor 4-A precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor SEK-1) (xSEK-1) Length = 986 Score = 36.6 bits (83), Expect = 0.059 Identities = 24/93 (25%), Positives = 43/93 (46%), Gaps = 1/93 (1%) Frame = +1 Query: 325 VAVKKL-LNNLGQAEKEFRVEVEAIGHVRHKNLVRLLGYCVEGTQRILVYEYVNNGNLEQ 501 VA+K L + ++F E +G H N++ L G + +++ EY+ NG+L+ Sbjct: 649 VAIKTLKAGYTDKQRRDFLSEASIMGQFDHPNIIHLEGVVTKCKPVMIITEYMENGSLDA 708 Query: 502 WLHGAMSHRGSLTWEARIKILLGTAKALAYLHE 600 +L + G T + IL G + YL + Sbjct: 709 FLR---KNDGRFTVIQLVGILRGIGSGMKYLSD 738
>YSK4_HUMAN (Q56UN5) SPS1/STE20-related protein kinase YSK4 (EC 2.7.11.1)| (Regulated in COPD, protein kinase) Length = 1328 Score = 36.6 bits (83), Expect = 0.059 Identities = 29/101 (28%), Positives = 49/101 (48%), Gaps = 6/101 (5%) Frame = +1 Query: 316 GTPVAVKKLL---NNLGQAEKEFRV---EVEAIGHVRHKNLVRLLGYCVEGTQRILVYEY 477 G +AVK++ +N AEKE+R EV+ + ++H N+V LG C++ + E+ Sbjct: 1083 GQLIAVKQVALDTSNKLAAEKEYRKLQEEVDLLKALKHVNIVAYLGTCLQENTVSIFMEF 1142 Query: 478 VNNGNLEQWLHGAMSHRGSLTWEARIKILLGTAKALAYLHE 600 V G++ ++ G L K + +AYLHE Sbjct: 1143 VPGGSIS----SIINRFGPLPEMVFCKYTKQILQGVAYLHE 1179
>CSF1R_MOUSE (P09581) Macrophage colony-stimulating factor 1 receptor precursor| (CSF-1-R) (EC 2.7.10.1) (Fms proto-oncogene) (c-fms) Length = 977 Score = 36.6 bits (83), Expect = 0.059 Identities = 23/63 (36%), Positives = 37/63 (58%), Gaps = 2/63 (3%) Frame = +1 Query: 325 VAVKKLLNNLGQAEKEFRV-EVEAIGHV-RHKNLVRLLGYCVEGTQRILVYEYVNNGNLE 498 VAVK L + EKE + E++ + H+ +H+N+V LLG C G +++ EY G+L Sbjct: 611 VAVKMLKSTAHADEKEALMSELKIMSHLGQHENIVNLLGACTHGGPVLVITEYCCYGDLL 670 Query: 499 QWL 507 +L Sbjct: 671 NFL 673
>M3K1_RAT (Q62925) Mitogen-activated protein kinase kinase kinase 1 (EC| 2.7.11.25) (MAPK/ERK kinase kinase 1) (MEK kinase 1) (MEKK 1) Length = 1493 Score = 36.6 bits (83), Expect = 0.059 Identities = 27/101 (26%), Positives = 50/101 (49%), Gaps = 6/101 (5%) Frame = +1 Query: 316 GTPVAVKKL--LNNLGQAEKE----FRVEVEAIGHVRHKNLVRLLGYCVEGTQRILVYEY 477 GT +AVK++ + N ++E R E+ + H+ H N++R+LG E + L E+ Sbjct: 1247 GTLMAVKQVTYVRNTSSEQEEVVEALREEIRMMSHLNHPNIIRMLGATCEKSNYNLFIEW 1306 Query: 478 VNNGNLEQWLHGAMSHRGSLTWEARIKILLGTAKALAYLHE 600 + ++ L + + S+ ++L G L+YLHE Sbjct: 1307 MAGASVAHLLSKYGAFKESVVINYTEQLLRG----LSYLHE 1343
>SRMS_HUMAN (Q9H3Y6) Tyrosine-protein kinase Srms (EC 2.7.10.2)| Length = 488 Score = 36.6 bits (83), Expect = 0.059 Identities = 28/97 (28%), Positives = 47/97 (48%), Gaps = 4/97 (4%) Frame = +1 Query: 322 PVAVKKLLNNLGQAEKEFRVEVEAIGHVRHKNLVRLLGYCVEGTQRILVYEYVNNGNLEQ 501 PVA+K ++ + + E++ + +RH+ L+RL C G +V E + GNL+ Sbjct: 254 PVAIK-VIKSANMKLTDLAKEIQTLKGLRHERLIRLHAVCSGGEPVYIVTELMRKGNLQA 312 Query: 502 WLHGAMSHRGSLTWEARIKILLG----TAKALAYLHE 600 +L G R R+ LLG A+ ++YL E Sbjct: 313 FL-GTPEGRA-----LRLPPLLGFACQVAEGMSYLEE 343
>RIPK1_MOUSE (Q60855) Receptor-interacting serine/threonine-protein kinase 1 (EC| 2.7.11.1) (Serine/threonine-protein kinase RIP) (Cell death protein RIP) (Receptor-interacting protein) Length = 656 Score = 36.6 bits (83), Expect = 0.059 Identities = 29/94 (30%), Positives = 47/94 (50%), Gaps = 2/94 (2%) Frame = +1 Query: 325 VAVKKLLNNLGQAE-KEFRVEVEAIGH-VRHKNLVRLLGYCVEGTQRILVYEYVNNGNLE 498 V +KK+ +AE E +E + H +RH +V+LLG +E LV EY+ GNL Sbjct: 42 VILKKVYTGPNRAEYNEVLLEEGKMMHRLRHSRVVKLLGIIIEEGNYSLVMEYMEKGNLM 101 Query: 499 QWLHGAMSHRGSLTWEARIKILLGTAKALAYLHE 600 L + SL + +I++ + + YLH+ Sbjct: 102 HVLKTQIDVPLSL----KGRIIVEAIEGMCYLHD 131
>GUC2C_CAVPO (P70106) Heat-stable enterotoxin receptor precursor (GC-C)| (Intestinal guanylate cyclase) (EC 4.6.1.2) (STA receptor) (Guanylyl cyclase C) Length = 1076 Score = 36.2 bits (82), Expect = 0.077 Identities = 23/93 (24%), Positives = 46/93 (49%), Gaps = 2/93 (2%) Frame = +1 Query: 331 VKKLLNNLGQAEKEFRVEVEAIGHVRHKNLVRLLGYCVEGTQRILVYEYVNNGNLEQWLH 510 +K L + G ++ ++E++ + +L + G T+ V EY G+L + L+ Sbjct: 518 LKDLKYSDGNFSEKQKIELDKLLPSDFYSLTKFYGTVKLDTRIFGVIEYCERGSLREVLN 577 Query: 511 GAMSHRGS--LTWEARIKILLGTAKALAYLHEA 603 +S+ + WE +I +L AK ++YLH + Sbjct: 578 ETISYPDGTIMGWEFKISVLYDIAKGMSYLHSS 610
>M3K9_HUMAN (P80192) Mitogen-activated protein kinase kinase kinase 9 (EC| 2.7.11.25) (Mixed lineage kinase 1) Length = 1104 Score = 36.2 bits (82), Expect = 0.077 Identities = 27/100 (27%), Positives = 44/100 (44%), Gaps = 5/100 (5%) Frame = +1 Query: 316 GTPVAVKKLLNN----LGQAEKEFRVEVEAIGHVRHKNLVRLLGYCVEGTQRILVYEYVN 483 G VAVK ++ + Q + R E + ++H N++ L G C++ LV E+ Sbjct: 165 GDEVAVKAARHDPDEDISQTIENVRQEAKLFAMLKHPNIIALRGVCLKEPNLCLVMEFAR 224 Query: 484 NGNLEQWLHGAMSHRGSL-TWEARIKILLGTAKALAYLHE 600 G L + L G L W +I A+ + YLH+ Sbjct: 225 GGPLNRVLSGKRIPPDILVNWAVQI------ARGMNYLHD 258
>GUC2F_HUMAN (P51841) Retinal guanylyl cyclase 2 precursor (EC 4.6.1.2)| (Guanylate cyclase 2F, retinal) (RETGC-2) (Rod outer segment membrane guanylate cyclase 2) (ROS-GC2) (Guanylate cyclase F) (GC-F) Length = 1108 Score = 36.2 bits (82), Expect = 0.077 Identities = 21/70 (30%), Positives = 35/70 (50%) Frame = +1 Query: 388 EAIGHVRHKNLVRLLGYCVEGTQRILVYEYVNNGNLEQWLHGAMSHRGSLTWEARIKILL 567 E + +RH+N+ LLG+ + +V E+ + G+LE L + L W + +LL Sbjct: 596 EMMKDLRHENINPLLGFFYDSGMFAIVTEFCSRGSLEDIL---TNQDVKLDWMFKSSLLL 652 Query: 568 GTAKALAYLH 597 K + YLH Sbjct: 653 DLIKGMKYLH 662
>AURKB_HUMAN (Q96GD4) Serine/threonine-protein kinase 12 (EC 2.7.11.1) (Aurora-| and Ipl1-like midbody-associated protein 1) (AIM-1) (Aurora/IPL1-related kinase 2) (Aurora-related kinase 2) (STK-1) (Aurora-B) Length = 344 Score = 35.8 bits (81), Expect = 0.10 Identities = 30/96 (31%), Positives = 43/96 (44%), Gaps = 5/96 (5%) Frame = +1 Query: 325 VAVKKLLNNLGQAEKE-----FRVEVEAIGHVRHKNLVRLLGYCVEGTQRILVYEYVNNG 489 VA+K L + Q EKE R E+E H+ H N++RL Y + + L+ EY G Sbjct: 103 VALKVLFKS--QIEKEGVEHQLRREIEIQAHLHHPNILRLYNYFYDRRRIYLILEYAPRG 160 Query: 490 NLEQWLHGAMSHRGSLTWEARIKILLGTAKALAYLH 597 L + L + + T I+ A AL Y H Sbjct: 161 ELYKELQKSCTFDEQRT----ATIMEELADALMYCH 192
>ERBB3_RAT (Q62799) Receptor tyrosine-protein kinase erbB-3 precursor (EC| 2.7.10.1) (c-erbB3) Length = 1339 Score = 35.8 bits (81), Expect = 0.10 Identities = 29/94 (30%), Positives = 48/94 (51%), Gaps = 1/94 (1%) Frame = +1 Query: 322 PVAVKKLLNNLG-QAEKEFRVEVEAIGHVRHKNLVRLLGYCVEGTQRILVYEYVNNGNLE 498 PV +K + + G Q+ + + A+G + H ++VRLLG C G+ LV +Y+ G+L Sbjct: 736 PVCIKVIEDKSGRQSFQAVTDHMLAVGSLDHAHIVRLLGLC-PGSSLQLVTQYLPLGSL- 793 Query: 499 QWLHGAMSHRGSLTWEARIKILLGTAKALAYLHE 600 L HR +L + + + AK + YL E Sbjct: 794 --LDHVKQHRETLGPQLLLNWGVQIAKGMYYLEE 825
>ERBB3_MOUSE (Q61526) Receptor tyrosine-protein kinase erbB-3 precursor (EC| 2.7.10.1) (c-erbB3) (Glial growth factor receptor) Length = 1339 Score = 35.8 bits (81), Expect = 0.10 Identities = 29/94 (30%), Positives = 48/94 (51%), Gaps = 1/94 (1%) Frame = +1 Query: 322 PVAVKKLLNNLG-QAEKEFRVEVEAIGHVRHKNLVRLLGYCVEGTQRILVYEYVNNGNLE 498 PV +K + + G Q+ + + A+G + H ++VRLLG C G+ LV +Y+ G+L Sbjct: 736 PVCIKVIEDKSGRQSFQAVTDHMLAVGSLDHAHIVRLLGLC-PGSSLQLVTQYLPLGSL- 793 Query: 499 QWLHGAMSHRGSLTWEARIKILLGTAKALAYLHE 600 L HR +L + + + AK + YL E Sbjct: 794 --LDHVRQHRETLGPQLLLNWGVQIAKGMYYLEE 825
>FES_MOUSE (P16879) Proto-oncogene tyrosine-protein kinase Fes/Fps (EC| 2.7.10.2) (C-Fes) Length = 820 Score = 35.8 bits (81), Expect = 0.10 Identities = 22/66 (33%), Positives = 31/66 (46%), Gaps = 1/66 (1%) Frame = +1 Query: 313 NGTPVAVKKLLNNLGQAEK-EFRVEVEAIGHVRHKNLVRLLGYCVEGTQRILVYEYVNNG 489 + TPVAVK L K +F E + H N+VRL+G C + +V E V G Sbjct: 581 DNTPVAVKSCRETLPPDLKAKFLQEARILKQYNHPNIVRLIGVCTQKQPIYIVMELVQGG 640 Query: 490 NLEQWL 507 + +L Sbjct: 641 DFLTFL 646
>ULK1_HUMAN (O75385) Serine/threonine-protein kinase ULK1 (EC 2.7.11.1)| (Unc-51-like kinase 1) Length = 1050 Score = 35.8 bits (81), Expect = 0.10 Identities = 20/63 (31%), Positives = 34/63 (53%), Gaps = 1/63 (1%) Frame = +1 Query: 325 VAVKKL-LNNLGQAEKEFRVEVEAIGHVRHKNLVRLLGYCVEGTQRILVYEYVNNGNLEQ 501 VAVK + NL +++ E++ + ++H+N+V L + LV EY N G+L Sbjct: 43 VAVKCINKKNLAKSQTLLGKEIKILKELKHENIVALYDFQEMANSVYLVMEYCNGGDLAD 102 Query: 502 WLH 510 +LH Sbjct: 103 YLH 105
>ROR2_MOUSE (Q9Z138) Tyrosine-protein kinase transmembrane receptor ROR2| precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase, receptor-related 2) (mROR2) Length = 944 Score = 35.8 bits (81), Expect = 0.10 Identities = 19/62 (30%), Positives = 34/62 (54%), Gaps = 1/62 (1%) Frame = +1 Query: 325 VAVKKLLNNL-GQAEKEFRVEVEAIGHVRHKNLVRLLGYCVEGTQRILVYEYVNNGNLEQ 501 VA+K L + G +EFR E ++H N+V LLG + +++ Y ++G+L + Sbjct: 504 VAIKTLKDKAEGPLREEFRQEAMLRARLQHPNIVCLLGVVTKDQPLSMIFSYCSHGDLHE 563 Query: 502 WL 507 +L Sbjct: 564 FL 565
>BMX_HUMAN (P51813) Cytoplasmic tyrosine-protein kinase BMX (EC 2.7.10.2)| (Bone marrow tyrosine kinase gene in chromosome X protein) (Epithelial and endothelial tyrosine kinase) (ETK) (NTK38) Length = 675 Score = 35.8 bits (81), Expect = 0.10 Identities = 22/86 (25%), Positives = 40/86 (46%) Frame = +1 Query: 337 KLLNNLGQAEKEFRVEVEAIGHVRHKNLVRLLGYCVEGTQRILVYEYVNNGNLEQWLHGA 516 K++ +E EF E + + + H LV+ G C + +V EY++NG L +L Sbjct: 445 KMIKEGSMSEDEFFQEAQTMMKLSHPKLVKFYGVCSKEYPIYIVTEYISNGCLLNYLR-- 502 Query: 517 MSHRGSLTWEARIKILLGTAKALAYL 594 SH L +++ + +A+L Sbjct: 503 -SHGKGLEPSQLLEMCYDVCEGMAFL 527
>AURKB_RAT (O55099) Serine/threonine-protein kinase 12 (EC 2.7.11.1) (Aurora-| and Ipl1-like midbody-associated protein 1) (AIM-1) (Aurora-B) Length = 343 Score = 35.8 bits (81), Expect = 0.10 Identities = 20/79 (25%), Positives = 37/79 (46%) Frame = +1 Query: 364 EKEFRVEVEAIGHVRHKNLVRLLGYCVEGTQRILVYEYVNNGNLEQWLHGAMSHRGSLTW 543 E + R E+E H++H N+++L Y + + L+ EY G L+ + G+ Sbjct: 122 EHQLRREIEIQAHLKHPNILQLYNYFYDQQRIYLILEYAPRGE----LYKELQKSGTFDE 177 Query: 544 EARIKILLGTAKALAYLHE 600 + I+ + AL Y H+ Sbjct: 178 QRTATIMEELSDALMYCHK 196
>ULK1_MOUSE (O70405) Serine/threonine-protein kinase ULK1 (EC 2.7.11.1)| (Unc-51-like kinase 1) (Serine/threonine-protein kinase Unc51.1) Length = 1051 Score = 35.8 bits (81), Expect = 0.10 Identities = 20/63 (31%), Positives = 34/63 (53%), Gaps = 1/63 (1%) Frame = +1 Query: 325 VAVKKL-LNNLGQAEKEFRVEVEAIGHVRHKNLVRLLGYCVEGTQRILVYEYVNNGNLEQ 501 VAVK + NL +++ E++ + ++H+N+V L + LV EY N G+L Sbjct: 43 VAVKCINKKNLAKSQTLLGKEIKILKELKHENIVALYDFQEMANSVYLVMEYCNGGDLAD 102 Query: 502 WLH 510 +LH Sbjct: 103 YLH 105
>CEK2_CHICK (P18460) Tyrosine kinase receptor CEK2 precursor (EC 2.7.10.1)| Length = 806 Score = 35.8 bits (81), Expect = 0.10 Identities = 21/63 (33%), Positives = 36/63 (57%), Gaps = 2/63 (3%) Frame = +1 Query: 325 VAVKKLLNNLGQAEKEFRV-EVEAIGHV-RHKNLVRLLGYCVEGTQRILVYEYVNNGNLE 498 VAVK L ++ + V E+E + + +HKN++ LLG C + ++ EY + GNL Sbjct: 499 VAVKMLKDDATDKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVLVEYASKGNLR 558 Query: 499 QWL 507 ++L Sbjct: 559 EYL 561
>ANPRA_RAT (P18910) Atrial natriuretic peptide receptor A precursor (ANP-A)| (ANPRA) (GC-A) (Guanylate cyclase) (EC 4.6.1.2) (NPR-A) (Atrial natriuretic peptide A-type receptor) Length = 1057 Score = 35.4 bits (80), Expect = 0.13 Identities = 22/94 (23%), Positives = 45/94 (47%) Frame = +1 Query: 316 GTPVAVKKLLNNLGQAEKEFRVEVEAIGHVRHKNLVRLLGYCVEGTQRILVYEYVNNGNL 495 G VAVK++ + ++ E++ + V++++L R +G C + ++ EY G+L Sbjct: 557 GNLVAVKRVNRKRIELTRKVLFELKHMRDVQNEHLTRFVGACTDPPNICILTEYCPRGSL 616 Query: 496 EQWLHGAMSHRGSLTWEARIKILLGTAKALAYLH 597 + L + +L W R + K + +LH Sbjct: 617 QDILE---NESITLDWMFRYSLTNDIVKGMLFLH 647
>ANPRA_MOUSE (P18293) Atrial natriuretic peptide receptor A precursor (ANP-A)| (ANPRA) (GC-A) (Guanylate cyclase) (EC 4.6.1.2) (NPR-A) (Atrial natriuretic peptide A-type receptor) Length = 1057 Score = 35.4 bits (80), Expect = 0.13 Identities = 22/94 (23%), Positives = 45/94 (47%) Frame = +1 Query: 316 GTPVAVKKLLNNLGQAEKEFRVEVEAIGHVRHKNLVRLLGYCVEGTQRILVYEYVNNGNL 495 G VAVK++ + ++ E++ + V++++L R +G C + ++ EY G+L Sbjct: 557 GNLVAVKRVNRKRIELTRKVLFELKHMRDVQNEHLTRFVGACTDPPNICILTEYCPRGSL 616 Query: 496 EQWLHGAMSHRGSLTWEARIKILLGTAKALAYLH 597 + L + +L W R + K + +LH Sbjct: 617 QDILE---NESITLDWMFRYSLTNDIVKGMLFLH 647
>LET23_CAEEL (P24348) Receptor tyrosine-protein kinase let-23 precursor (EC| 2.7.10.1) (Lethal protein 23) Length = 1367 Score = 35.4 bits (80), Expect = 0.13 Identities = 24/93 (25%), Positives = 44/93 (47%) Frame = +1 Query: 322 PVAVKKLLNNLGQAEKEFRVEVEAIGHVRHKNLVRLLGYCVEGTQRILVYEYVNNGNLEQ 501 PVA+K + Q + E E + +RH NL++++G+C+ +V Y GNL+ Sbjct: 959 PVAIKVFQTDQSQTD-EMLEEATNMFRLRHDNLLKIIGFCMHDDGLKIVTIYRPLGNLQN 1017 Query: 502 WLHGAMSHRGSLTWEARIKILLGTAKALAYLHE 600 +L H+ +L ++ A + YL + Sbjct: 1018 FL---KLHKENLGAREQVLYCYQIASGMQYLEK 1047
>EPA4B_XENLA (Q91694) Ephrin type-A receptor 4-B precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor PAG) (Pagliaccio) Length = 985 Score = 35.4 bits (80), Expect = 0.13 Identities = 23/93 (24%), Positives = 43/93 (46%), Gaps = 1/93 (1%) Frame = +1 Query: 325 VAVKKL-LNNLGQAEKEFRVEVEAIGHVRHKNLVRLLGYCVEGTQRILVYEYVNNGNLEQ 501 VA+K L + ++F E +G H N++ L G + +++ EY+ NG+L+ Sbjct: 649 VAIKTLKAGYTDKQRRDFLSEASIMGQFDHPNIIHLEGVVTKCKPVMIITEYMENGSLDA 708 Query: 502 WLHGAMSHRGSLTWEARIKILLGTAKALAYLHE 600 +L + G T + +L G + YL + Sbjct: 709 FLR---KNDGRFTVIQLVGMLRGIGSGMKYLSD 738
>JAK1_CYPCA (Q09178) Tyrosine-protein kinase Jak1 (EC 2.7.10.2) (Janus kinase| 1) (Jak-1) Length = 1156 Score = 35.4 bits (80), Expect = 0.13 Identities = 27/94 (28%), Positives = 45/94 (47%), Gaps = 4/94 (4%) Frame = +1 Query: 331 VKKLLNNLGQAEKE----FRVEVEAIGHVRHKNLVRLLGYCVEGTQRILVYEYVNNGNLE 498 VK +L LG ++ F + + HK++ L G CV + I+V E+V G L+ Sbjct: 619 VKVILKVLGSGHRDISLAFFETASMMRQISHKHIALLYGVCVRHQENIMVEEFVQYGPLD 678 Query: 499 QWLHGAMSHRGSLTWEARIKILLGTAKALAYLHE 600 ++ S S W+ ++ L A AL+YL + Sbjct: 679 LFMR-RQSIPLSTAWKFQVAKQL--AGALSYLED 709
>EPHA4_MOUSE (Q03137) Ephrin type-A receptor 4 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor SEK) (MPK-3) Length = 986 Score = 35.4 bits (80), Expect = 0.13 Identities = 23/93 (24%), Positives = 43/93 (46%), Gaps = 1/93 (1%) Frame = +1 Query: 325 VAVKKL-LNNLGQAEKEFRVEVEAIGHVRHKNLVRLLGYCVEGTQRILVYEYVNNGNLEQ 501 VA+K L + ++F E +G H N++ L G + +++ EY+ NG+L+ Sbjct: 650 VAIKTLKAGYTDKQRRDFLSEASIMGQFDHPNIIHLEGVVTKCKPVMIITEYMENGSLDA 709 Query: 502 WLHGAMSHRGSLTWEARIKILLGTAKALAYLHE 600 +L + G T + +L G + YL + Sbjct: 710 FLR---KNDGRFTVIQLVGMLRGIGSGMKYLSD 739
>EPHA4_HUMAN (P54764) Ephrin type-A receptor 4 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor SEK) (Receptor protein-tyrosine kinase HEK8) Length = 986 Score = 35.4 bits (80), Expect = 0.13 Identities = 23/93 (24%), Positives = 43/93 (46%), Gaps = 1/93 (1%) Frame = +1 Query: 325 VAVKKL-LNNLGQAEKEFRVEVEAIGHVRHKNLVRLLGYCVEGTQRILVYEYVNNGNLEQ 501 VA+K L + ++F E +G H N++ L G + +++ EY+ NG+L+ Sbjct: 650 VAIKTLKAGYTDKQRRDFLSEASIMGQFDHPNIIHLEGVVTKCKPVMIITEYMENGSLDA 709 Query: 502 WLHGAMSHRGSLTWEARIKILLGTAKALAYLHE 600 +L + G T + +L G + YL + Sbjct: 710 FLR---KNDGRFTVIQLVGMLRGIGSGMKYLSD 739
>EPHA4_CHICK (Q07496) Ephrin type-A receptor 4 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor CEK8) Length = 986 Score = 35.4 bits (80), Expect = 0.13 Identities = 23/93 (24%), Positives = 43/93 (46%), Gaps = 1/93 (1%) Frame = +1 Query: 325 VAVKKL-LNNLGQAEKEFRVEVEAIGHVRHKNLVRLLGYCVEGTQRILVYEYVNNGNLEQ 501 VA+K L + ++F E +G H N++ L G + +++ EY+ NG+L+ Sbjct: 650 VAIKTLKAGYTDKQRRDFLSEASIMGQFDHPNIIHLEGVVTKCKPVMIITEYMENGSLDA 709 Query: 502 WLHGAMSHRGSLTWEARIKILLGTAKALAYLHE 600 +L + G T + +L G + YL + Sbjct: 710 FLR---KNDGRFTVIQLVGMLRGIGSGMKYLSD 739
>MLTK_MOUSE (Q9ESL4) Mitogen-activated protein kinase kinase kinase MLT (EC| 2.7.11.25) (MLK-like mitogen-activated protein triple kinase) (Leucine zipper-and sterile alpha motif kinase ZAK) (Sterile alpha motif- and leucine zipper-containing kinase AZK) ( Length = 802 Score = 35.4 bits (80), Expect = 0.13 Identities = 26/95 (27%), Positives = 43/95 (45%), Gaps = 4/95 (4%) Frame = +1 Query: 325 VAVKKLLNNLGQAEKEFRVEVEAIGHVRHKNLVRLLGYCVEGTQRILVYEYVNNGNLEQW 504 VAVKKLL + E E + + H+N+++ G +E +V EY + G+L + Sbjct: 42 VAVKKLL--------KIEKEAEILSVLSHRNIIQFYGVILEPPNYGIVTEYASLGSLYDY 93 Query: 505 LHG----AMSHRGSLTWEARIKILLGTAKALAYLH 597 ++ M +TW + AK + YLH Sbjct: 94 INSNRSEEMDMEHIMTWATDV------AKGMHYLH 122
>MLTK_HUMAN (Q9NYL2) Mitogen-activated protein kinase kinase kinase MLT (EC| 2.7.11.25) (MLK-like mitogen-activated protein triple kinase) (Leucine zipper-and sterile alpha motif-containing kinase) (Sterile alpha motif- and leucine zipper-containing kinase Length = 800 Score = 35.4 bits (80), Expect = 0.13 Identities = 26/95 (27%), Positives = 43/95 (45%), Gaps = 4/95 (4%) Frame = +1 Query: 325 VAVKKLLNNLGQAEKEFRVEVEAIGHVRHKNLVRLLGYCVEGTQRILVYEYVNNGNLEQW 504 VAVKKLL + E E + + H+N+++ G +E +V EY + G+L + Sbjct: 42 VAVKKLL--------KIEKEAEILSVLSHRNIIQFYGVILEPPNYGIVTEYASLGSLYDY 93 Query: 505 LHGAMSHRGS----LTWEARIKILLGTAKALAYLH 597 ++ S +TW + AK + YLH Sbjct: 94 INSNRSEEMDMDHIMTWATDV------AKGMHYLH 122 Database: uniprot_sprot.fasta Posted date: May 25, 2006 5:36 PM Number of letters in database: 80,573,946 Number of sequences in database: 219,361 Lambda K H 0.318 0.135 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 88,301,317 Number of Sequences: 219361 Number of extensions: 1808940 Number of successful extensions: 5414 Number of sequences better than 10.0: 460 Number of HSP's better than 10.0 without gapping: 5182 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 5363 length of database: 80,573,946 effective HSP length: 107 effective length of database: 57,102,319 effective search space used: 5424720305 frameshift window, decay const: 50, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
