ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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| Clone Name | basd2f06 |
|---|---|
| Clone Library Name | barley_pub |
>FA62A_PONPY (Q5RAG2) Protein FAM62A| Length = 1104 Score = 67.8 bits (164), Expect = 2e-11 Identities = 53/190 (27%), Positives = 88/190 (46%) Frame = +2 Query: 32 GKSDPFAVLYIRPLSAKTKKSKTINNDLNPIWNEHYEFVVEDSSTQHLTVKIYDDEGLQP 211 GKSDP+ L L+ ++ +S + DLNP WNE +E +V Q L V+++D + L Sbjct: 672 GKSDPYVKL---KLAGRSFRSHVVREDLNPRWNEVFEVIVTSVPGQELEVEVFDKD-LDK 727 Query: 212 SEIIGCARVDLSDIMPGKVKDVWLELVKDLEIQRDKKPRGQVHLELLYYPFDKQEGVSNP 391 + +G +V L+ ++ D WL L + P G++HL L + P Sbjct: 728 DDFLGRCKVSLTTVLNSGFLDEWLTL--------EDVPSGRLHLRL-------ERLTPRP 772 Query: 392 FASQIQLTSLEKVLKTESNGYDVNQRKNVITRGVLSVTVISAEDIPAMDVMGKADPFVVL 571 A++ LE+VL+ N Q+ + +LS+ + AED+P P+ L Sbjct: 773 TAAE-----LEEVLQV--NSLIQTQKSAELAAALLSIYMERAEDLPLRKGTKHPSPYATL 825 Query: 572 YLKKGETKKK 601 + G+T K Sbjct: 826 TV--GDTSHK 833 Score = 59.3 bits (142), Expect = 8e-09 Identities = 46/183 (25%), Positives = 83/183 (45%) Frame = +2 Query: 32 GKSDPFAVLYIRPLSAKTKKSKTINNDLNPIWNEHYEFVVEDSSTQHLTVKIYDDEGLQP 211 GKSDP+A++ L +T S+ I+ +LNP W E YE +V + Q + V+++D + Sbjct: 354 GKSDPYALVR---LGTQTFCSRVIDEELNPQWGETYEVMVHEVPGQEIEVEVFDKDP-DK 409 Query: 212 SEIIGCARVDLSDIMPGKVKDVWLELVKDLEIQRDKKPRGQVHLELLYYPFDKQEGVSNP 391 + +G ++D+ ++ V D W L + +GQVHL L + Sbjct: 410 DDFLGRMKLDVGKVLQAGVLDDWFPL---------QGGQGQVHLRLEWLSL--------- 451 Query: 392 FASQIQLTSLEKVLKTESNGYDVNQRKNVITRGVLSVTVISAEDIPAMDVMGKADPFVVL 571 L+ EK+ + V+ R + +L V + A+D+P + +P V L Sbjct: 452 ------LSDAEKLEQVLQWNQGVSSRPEPPSAAILVVYLDRAQDLPLKKGNKEPNPMVQL 505 Query: 572 YLK 580 ++ Sbjct: 506 SIQ 508 Score = 40.8 bits (94), Expect = 0.003 Identities = 41/182 (22%), Positives = 74/182 (40%), Gaps = 17/182 (9%) Frame = +2 Query: 83 TKKSKTINNDLNPIWNEHYEFVVEDSSTQHLTVKIYDDEGLQPSEIIGCARVDLSDIM-- 256 T++SK + + P+W E + F ++D +Q L V++ DD + +G + L+ ++ Sbjct: 511 TQESKAVYSTNCPVWEEAFRFFLQDPQSQELDVQVKDD---SRALTLGALTLPLARLLTA 567 Query: 257 PGKVKDVWLELVKDLEIQRDKKPRGQVHLEL----LYYP-----FDKQEGVSNPFASQIQ 409 P + D W +L P +++++L LY F G + + Sbjct: 568 PELILDQWFQL-------SSSGPNSRLYMKLVMRILYLDSSEICFPTVPGCPGAWDVDSE 620 Query: 410 LTSLEKVLKTESNGYDVNQRKNVITRGVLSVTVISAEDIPAMD------VMGKADPFVVL 571 + T VL + V+ A+D+ A D V GK+DP+V L Sbjct: 621 NPQRGSSVDAPPRPCHTTPDSQFGTEHVLRIHVLEAQDLIAKDRFLGGLVKGKSDPYVKL 680 Query: 572 YL 577 L Sbjct: 681 KL 682 Score = 32.3 bits (72), Expect = 1.1 Identities = 17/71 (23%), Positives = 38/71 (53%) Frame = +2 Query: 44 PFAVLYIRPLSAKTKKSKTINNDLNPIWNEHYEFVVEDSSTQHLTVKIYDDEGLQPSEII 223 P+A L + S KTK T++ P+W+E F++ T++L +++ + + ++ Sbjct: 821 PYATLTVGDTSHKTK---TVSQTSAPVWDESASFLIRKPHTENLELQVRG----EGTGVL 873 Query: 224 GCARVDLSDIM 256 G + LS+++ Sbjct: 874 GSLSLPLSELL 884
>FA62A_MOUSE (Q3U7R1) Protein FAM62A (Membrane bound C2 domain-containing protein)| Length = 1092 Score = 67.8 bits (164), Expect = 2e-11 Identities = 52/190 (27%), Positives = 89/190 (46%) Frame = +2 Query: 32 GKSDPFAVLYIRPLSAKTKKSKTINNDLNPIWNEHYEFVVEDSSTQHLTVKIYDDEGLQP 211 GKSDP+ L + + K+ ++ + DLNP WNE +E +V Q L ++++D + L Sbjct: 659 GKSDPYVKLKV---AGKSFRTHVVREDLNPRWNEVFEVIVTSIPGQELEIEVFDKD-LDK 714 Query: 212 SEIIGCARVDLSDIMPGKVKDVWLELVKDLEIQRDKKPRGQVHLELLYYPFDKQEGVSNP 391 + +G +V L+ ++ D WL L + P G++HL L + P Sbjct: 715 DDFLGRYKVSLTTVLNSGFLDEWLTL--------EDVPSGRLHLRL-------ERLTPRP 759 Query: 392 FASQIQLTSLEKVLKTESNGYDVNQRKNVITRGVLSVTVISAEDIPAMDVMGKADPFVVL 571 A++ LE+VL+ N Q+ + + +LSV + AED+P P+ + Sbjct: 760 TAAE-----LEEVLQV--NSLIQTQKSSELAAALLSVFLERAEDLPLRKGTKPPSPYATI 812 Query: 572 YLKKGETKKK 601 + GET K Sbjct: 813 TV--GETSHK 820 Score = 56.6 bits (135), Expect = 5e-08 Identities = 44/180 (24%), Positives = 79/180 (43%) Frame = +2 Query: 32 GKSDPFAVLYIRPLSAKTKKSKTINNDLNPIWNEHYEFVVEDSSTQHLTVKIYDDEGLQP 211 GKSDP+A++ + +T S+ I+ +LNP W E YE +V + Q + V+++D + Sbjct: 344 GKSDPYALVRV---GTQTFCSRVIDEELNPHWGETYEVIVHEVPGQEIEVEVFDKDP-DK 399 Query: 212 SEIIGCARVDLSDIMPGKVKDVWLELVKDLEIQRDKKPRGQVHLELLYYPFDKQEGVSNP 391 + +G ++D+ ++ V D W L + +GQVHL L + Sbjct: 400 DDFLGRMKLDVGKVLQAGVLDNWYPL---------QGGQGQVHLRLEWLSL--------- 441 Query: 392 FASQIQLTSLEKVLKTESNGYDVNQRKNVITRGVLSVTVISAEDIPAMDVMGKADPFVVL 571 L EK+ + + R + +L V + A+D+P + +P V L Sbjct: 442 ------LPDAEKLDQVLQWNRGITSRPEPPSAAILVVYLDRAQDLPLKKGNKEPNPMVQL 495 Score = 50.4 bits (119), Expect = 4e-06 Identities = 43/177 (24%), Positives = 78/177 (44%), Gaps = 14/177 (7%) Frame = +2 Query: 83 TKKSKTINNDLNPIWNEHYEFVVEDSSTQHLTVKIYDDEGLQPSEIIGCARVDLSDIMPG 262 T++SK + +P+W E + F ++D +Q L V++ DD + +G + L+ ++ Sbjct: 501 TRESKATYSTNSPVWEEAFRFFLQDPRSQELDVQVKDD---SRALTLGALTLPLARLLTA 557 Query: 263 K--VKDVWLELVKDLEIQRDKKPRGQVHLEL----LYYPFDKQEGVSNPFASQIQLTSLE 424 D W +L P +++++L LY + + + P A SLE Sbjct: 558 SELTLDQWFQL-------SSSGPNSRLYMKLVMRILYLDYSEIRFPTVPGAQDWDRESLE 610 Query: 425 KVLKTES--NGYDVNQRKNVITRGVLSVTVISAEDIPAMD------VMGKADPFVVL 571 ++ Y + T VL + V+ A+D+ A D V GK+DP+V L Sbjct: 611 TGSSVDAPPRPYHTTPNSHFGTENVLRIHVLEAQDLIAKDRFLGGLVKGKSDPYVKL 667
>FA62A_HUMAN (Q9BSJ8) Protein FAM62A (Membrane bound C2 domain-containing protein)| Length = 1104 Score = 67.0 bits (162), Expect = 4e-11 Identities = 52/190 (27%), Positives = 86/190 (45%) Frame = +2 Query: 32 GKSDPFAVLYIRPLSAKTKKSKTINNDLNPIWNEHYEFVVEDSSTQHLTVKIYDDEGLQP 211 GKSDP+ L L+ ++ +S + DLNP WNE +E +V Q L V+++D + L Sbjct: 672 GKSDPYVKL---KLAGRSFRSHVVREDLNPRWNEVFEVIVTSVPGQELEVEVFDKD-LDK 727 Query: 212 SEIIGCARVDLSDIMPGKVKDVWLELVKDLEIQRDKKPRGQVHLELLYYPFDKQEGVSNP 391 + +G +V L+ ++ D WL L + P G++HL L + P Sbjct: 728 DDFLGRCKVRLTTVLNSGFLDEWLTL--------EDVPSGRLHLRL-------ERLTPRP 772 Query: 392 FASQIQLTSLEKVLKTESNGYDVNQRKNVITRGVLSVTVISAEDIPAMDVMGKADPFVVL 571 A++ LE+VL+ N Q+ + +LS+ + AED+P P+ L Sbjct: 773 TAAE-----LEEVLQV--NSLIQTQKSAELAAALLSIYMERAEDLPLRKGTKHLSPYATL 825 Query: 572 YLKKGETKKK 601 + K K Sbjct: 826 TVGDSSHKTK 835 Score = 61.6 bits (148), Expect = 2e-09 Identities = 46/183 (25%), Positives = 85/183 (46%) Frame = +2 Query: 32 GKSDPFAVLYIRPLSAKTKKSKTINNDLNPIWNEHYEFVVEDSSTQHLTVKIYDDEGLQP 211 GKSDP+A++ L +T S+ I+ +LNP W E YE +V + Q + V+++D + Sbjct: 354 GKSDPYALVR---LGTQTFCSRVIDEELNPQWGETYEVMVHEVPGQEIEVEVFDKDP-DK 409 Query: 212 SEIIGCARVDLSDIMPGKVKDVWLELVKDLEIQRDKKPRGQVHLELLYYPFDKQEGVSNP 391 + +G ++D+ ++ V D W L + +GQVHL L + Sbjct: 410 DDFLGRMKLDVGKVLQASVLDDWFPL---------QGGQGQVHLRLEWLSL--------- 451 Query: 392 FASQIQLTSLEKVLKTESNGYDVNQRKNVITRGVLSVTVISAEDIPAMDVMGKADPFVVL 571 L+ EK+ + + V+ R + + +L V + A+D+P + +P V L Sbjct: 452 ------LSDAEKLEQVLQWNWGVSSRPDPPSAAILVVYLDRAQDLPLKKGNKEPNPMVQL 505 Query: 572 YLK 580 ++ Sbjct: 506 SIQ 508 Score = 40.8 bits (94), Expect = 0.003 Identities = 41/182 (22%), Positives = 74/182 (40%), Gaps = 17/182 (9%) Frame = +2 Query: 83 TKKSKTINNDLNPIWNEHYEFVVEDSSTQHLTVKIYDDEGLQPSEIIGCARVDLSDIM-- 256 T++SK + + P+W E + F ++D +Q L V++ DD + +G + L+ ++ Sbjct: 511 TQESKAVYSTNCPVWEEAFRFFLQDPQSQELDVQVKDD---SRALTLGALTLPLARLLTA 567 Query: 257 PGKVKDVWLELVKDLEIQRDKKPRGQVHLEL----LYYP-----FDKQEGVSNPFASQIQ 409 P + D W +L P +++++L LY F G + + Sbjct: 568 PELILDQWFQL-------SSSGPNSRLYMKLVMRILYLDSSEICFPTVPGCPGAWDVDSE 620 Query: 410 LTSLEKVLKTESNGYDVNQRKNVITRGVLSVTVISAEDIPAMD------VMGKADPFVVL 571 + T VL + V+ A+D+ A D V GK+DP+V L Sbjct: 621 NPQRGSSVDAPPRPCHTTPDSQFGTEHVLRIHVLEAQDLIAKDRFLGGLVKGKSDPYVKL 680 Query: 572 YL 577 L Sbjct: 681 KL 682 Score = 31.6 bits (70), Expect = 1.8 Identities = 18/71 (25%), Positives = 37/71 (52%) Frame = +2 Query: 44 PFAVLYIRPLSAKTKKSKTINNDLNPIWNEHYEFVVEDSSTQHLTVKIYDDEGLQPSEII 223 P+A L + S KTK TI+ P+W+E F++ T+ L +++ + + ++ Sbjct: 821 PYATLTVGDSSHKTK---TISQTSAPVWDESASFLIRKPHTESLELQVRG----EGTGVL 873 Query: 224 GCARVDLSDIM 256 G + LS+++ Sbjct: 874 GSLSLPLSELL 884
>FA62A_RAT (Q9Z1X1) Protein FAM62A (Membrane bound C2 domain-containing protein)| (vp115) Length = 1088 Score = 66.6 bits (161), Expect = 5e-11 Identities = 55/191 (28%), Positives = 90/191 (47%), Gaps = 1/191 (0%) Frame = +2 Query: 32 GKSDPFAVLYIRPLSAKTKKSKTINNDLNPIWNEHYEFVVEDSSTQHLTVKIYDDEGLQP 211 GKSDP+ L + S +T + DLNP WNE +E +V Q L ++++D + L Sbjct: 661 GKSDPYVKLKVAGRSLRTH---VVREDLNPRWNEVFEVIVTSIPGQELDIEVFDKD-LDK 716 Query: 212 SEIIGCARVDLSDIMPGKVKDVWLELVKDLEIQRDKKPRGQVHLELLYYPFDKQEGVS-N 388 + +G +V L+ ++ D WL L + P G++HL L E +S Sbjct: 717 DDFLGRYKVGLTTVLNSGFLDEWLTL--------EDVPSGRLHLRL--------ERLSPR 760 Query: 389 PFASQIQLTSLEKVLKTESNGYDVNQRKNVITRGVLSVTVISAEDIPAMDVMGKADPFVV 568 P A++ LE+VL+ N Q+ + + +LSV + +ED+P P+ + Sbjct: 761 PTAAE-----LEEVLQV--NSLIQTQKSSELAAALLSVYLERSEDLPLRKGTKPPSPYAI 813 Query: 569 LYLKKGETKKK 601 L + GET K Sbjct: 814 LTV--GETSHK 822 Score = 56.6 bits (135), Expect = 5e-08 Identities = 44/180 (24%), Positives = 79/180 (43%) Frame = +2 Query: 32 GKSDPFAVLYIRPLSAKTKKSKTINNDLNPIWNEHYEFVVEDSSTQHLTVKIYDDEGLQP 211 GKSDP+A++ + +T S+ I+ +LNP W E YE +V + Q + V+++D + Sbjct: 346 GKSDPYALVRV---GTQTFCSRVIDEELNPHWGETYEVIVHEVPGQEIEVEVFDKDP-DK 401 Query: 212 SEIIGCARVDLSDIMPGKVKDVWLELVKDLEIQRDKKPRGQVHLELLYYPFDKQEGVSNP 391 + +G ++D+ ++ V D W L + +GQVHL L + Sbjct: 402 DDFLGRMKLDVGKVLQAGVLDNWYPL---------QGGQGQVHLRLEWLSL--------- 443 Query: 392 FASQIQLTSLEKVLKTESNGYDVNQRKNVITRGVLSVTVISAEDIPAMDVMGKADPFVVL 571 L EK+ + + R + +L V + A+D+P + +P V L Sbjct: 444 ------LPDAEKLDQVLQWNRGITSRPEPPSAAILVVYLDRAQDLPLKKGNKEPNPMVQL 497 Score = 45.8 bits (107), Expect = 9e-05 Identities = 42/177 (23%), Positives = 75/177 (42%), Gaps = 14/177 (7%) Frame = +2 Query: 83 TKKSKTINNDLNPIWNEHYEFVVEDSSTQHLTVKIYDDEGLQPSEIIGCARVDLSDIMPG 262 T++SK + P+W E + F ++D +Q L V++ DD + +G + L+ ++ Sbjct: 503 TQESKATYSTNCPVWEEAFRFFLQDPRSQELDVQVKDD---SRALTLGALTLPLARLLTA 559 Query: 263 K--VKDVWLELVKDLEIQRDKKPRGQVHLEL----LYYPFDKQEGVSNPFASQIQLTSLE 424 D W +L P +++++L LY + + P A S E Sbjct: 560 SELTLDQWFQL-------SSSGPNSRLYMKLVMRILYLDSSEMRLPTEPGAQDWDSESPE 612 Query: 425 KVLKTES--NGYDVNQRKNVITRGVLSVTVISAEDIPAMD------VMGKADPFVVL 571 ++ Y + T VL + V+ A+D+ A D V GK+DP+V L Sbjct: 613 TGSSVDAPPRPYHTTPNSHFGTENVLRIHVLEAQDLIAKDRFLGGLVKGKSDPYVKL 669 Score = 29.6 bits (65), Expect = 6.9 Identities = 14/48 (29%), Positives = 25/48 (52%) Frame = +2 Query: 44 PFAVLYIRPLSAKTKKSKTINNDLNPIWNEHYEFVVEDSSTQHLTVKI 187 P+A+L + S KTK T++ PIW E F++ + L +++ Sbjct: 810 PYAILTVGETSHKTK---TVSQTSAPIWEESASFLIRKPHAESLELQV 854
>DOC2B_RAT (P70610) Double C2-like domain-containing protein beta (Doc2-beta)| Length = 412 Score = 64.3 bits (155), Expect = 3e-10 Identities = 54/194 (27%), Positives = 79/194 (40%), Gaps = 5/194 (2%) Frame = +2 Query: 32 GKSDPFAVLYIRPLSAKTKK--SKTINNDLNPIWNE---HYEFVVEDSSTQHLTVKIYDD 196 G +DP+ L++ P ++K K +KT+ N LNP WNE +Y ED + L + + D+ Sbjct: 160 GLADPYVKLHLLPGASKANKLRTKTLRNTLNPSWNETLTYYGITDEDMIRKTLRISVCDE 219 Query: 197 EGLQPSEIIGCARVDLSDIMPGKVKDVWLELVKDLEIQRDKKPRGQVHLELLYYPFDKQE 376 + + +E IG RV L + P K + L K L P DK E Sbjct: 220 DKFRHNEFIGETRVPLKKLKPNHTKTFSICLEKQL-------------------PVDKAE 260 Query: 377 GVSNPFASQIQLTSLEKVLKTESNGYDVNQRKNVITRGVLSVTVISAEDIPAMDVMGKAD 556 S E G + K + L V ++ + AMD G +D Sbjct: 261 DKS-----------------LEERGRILISLKYSSQKQGLLVGIVRCAHLAAMDANGYSD 303 Query: 557 PFVVLYLKKGETKK 598 P+V YLK KK Sbjct: 304 PYVKTYLKPDVDKK 317
>DOC2B_MOUSE (P70169) Double C2-like domain-containing protein beta (Doc2-beta)| Length = 412 Score = 64.3 bits (155), Expect = 3e-10 Identities = 54/194 (27%), Positives = 79/194 (40%), Gaps = 5/194 (2%) Frame = +2 Query: 32 GKSDPFAVLYIRPLSAKTKK--SKTINNDLNPIWNE---HYEFVVEDSSTQHLTVKIYDD 196 G +DP+ L++ P ++K K +KT+ N LNP WNE +Y ED + L + + D+ Sbjct: 160 GLADPYVKLHLLPGASKANKLRTKTLRNTLNPSWNETLTYYGITDEDMVRKTLRISVCDE 219 Query: 197 EGLQPSEIIGCARVDLSDIMPGKVKDVWLELVKDLEIQRDKKPRGQVHLELLYYPFDKQE 376 + + +E IG RV L + P K + L K L P DK E Sbjct: 220 DKFRHNEFIGETRVPLKKLKPNHTKTFSICLEKQL-------------------PVDKAE 260 Query: 377 GVSNPFASQIQLTSLEKVLKTESNGYDVNQRKNVITRGVLSVTVISAEDIPAMDVMGKAD 556 S E G + K + L V ++ + AMD G +D Sbjct: 261 DKS-----------------LEERGRILISLKYSSQKQGLLVGIVRCAHLAAMDANGYSD 303 Query: 557 PFVVLYLKKGETKK 598 P+V YLK KK Sbjct: 304 PYVKTYLKPDVDKK 317
>SY65_APLCA (P41823) Synaptotagmin-1 (Synaptotagmin I) (p65)| Length = 428 Score = 64.3 bits (155), Expect = 3e-10 Identities = 50/193 (25%), Positives = 84/193 (43%), Gaps = 3/193 (1%) Frame = +2 Query: 32 GKSDPFAVLYIRPLSAKTKKSKTINNDLNPIWNEHYEFVV--EDSSTQHLTVKIYDDEGL 205 G SDP+ +Y+ P K ++K LNP++NE + F V + ++ LT +YD + Sbjct: 187 GTSDPYVKVYLLPDKKKKYETKVHRKTLNPVFNESFTFKVPYAEVGSKILTFAVYDFDRF 246 Query: 206 QPSEIIGCARVDLSDIMPGKVKDVWLELVK-DLEIQRDKKPRGQVHLELLYYPFDKQEGV 382 + IG +V L+ I G+V + W +L D E +++ K G + L Y P Sbjct: 247 SKHDQIGQVQVPLNSIDLGRVVEDWKDLQSPDTESEKENK-LGDICFSLRYVP------- 298 Query: 383 SNPFASQIQLTSLEKVLKTESNGYDVNQRKNVITRGVLSVTVISAEDIPAMDVMGKADPF 562 T G L+V ++ A+++ MDV G +DP+ Sbjct: 299 ---------------------------------TAGKLTVVILEAKNLKKMDVGGLSDPY 325 Query: 563 VVLYLKKGETKKK 601 V + L +G + K Sbjct: 326 VKIALLQGTKRLK 338 Score = 42.0 bits (97), Expect = 0.001 Identities = 22/42 (52%), Positives = 28/42 (66%), Gaps = 5/42 (11%) Frame = +2 Query: 485 RGVLSVTVISAEDIPAMDVMGKADPFVVLYL-----KKGETK 595 +G LSV VI A D+P MD+ G +DP+V +YL KK ETK Sbjct: 167 KGELSVNVIQAADLPGMDMSGTSDPYVKVYLLPDKKKKYETK 208 Score = 35.0 bits (79), Expect = 0.17 Identities = 23/69 (33%), Positives = 35/69 (50%), Gaps = 4/69 (5%) Frame = +2 Query: 32 GKSDPFAVLYIRPLSAKTKKSKTI--NNDLNPIWNEHYEFVVEDSSTQHLT--VKIYDDE 199 G SDP+ + + + + KK KT N LNP +NE + F V Q +T + + D + Sbjct: 320 GLSDPYVKIALLQGTKRLKKKKTTIKKNTLNPYFNESFGFEVPFEQIQKVTLIITVVDYD 379 Query: 200 GLQPSEIIG 226 + SE IG Sbjct: 380 RIGTSEPIG 388
>RP3A_HUMAN (Q9Y2J0) Rabphilin-3A (Exophilin-1)| Length = 694 Score = 63.9 bits (154), Expect = 3e-10 Identities = 53/194 (27%), Positives = 87/194 (44%), Gaps = 5/194 (2%) Frame = +2 Query: 32 GKSDPFAVLYIRPLSAKTKK--SKTINNDLNPIWNE---HYEFVVEDSSTQHLTVKIYDD 196 G +DP+ L++ P ++K+ K +KT+ N NPIWNE ++ ED + L + + D+ Sbjct: 426 GLADPYVKLHLLPGASKSNKLRTKTLRNTRNPIWNETLVYHGITDEDMQRKTLRISVCDE 485 Query: 197 EGLQPSEIIGCARVDLSDIMPGKVKDVWLELVKDLEIQRDKKPRGQVHLELLYYPFDKQE 376 + +E IG R L + P + K+ + L + + ++R G LY Sbjct: 486 DKFGHNEFIGETRFSLKKLKPNQRKNFNICLERVIPMKR-AGTTGSARGMALY------- 537 Query: 377 GVSNPFASQIQLTSLEKVLKTESNGYDVNQRKNVITRGVLSVTVISAEDIPAMDVMGKAD 556 + +E+V E G + +G L V +I + AMD G +D Sbjct: 538 ----------EEEQVERVGDIEERGKILVSLMYSTQQGGLIVGIIRCVHLAAMDANGYSD 587 Query: 557 PFVVLYLKKGETKK 598 PFV L+LK KK Sbjct: 588 PFVKLWLKPDMGKK 601 Score = 31.6 bits (70), Expect = 1.8 Identities = 15/34 (44%), Positives = 21/34 (61%) Frame = +2 Query: 494 LSVTVISAEDIPAMDVMGKADPFVVLYLKKGETK 595 L T+I A+ + MD G ADP+V L+L G +K Sbjct: 409 LQCTIIKAKGLKPMDSNGLADPYVKLHLLPGASK 442
>RP3A_BOVIN (Q06846) Rabphilin-3A (Exophilin-1)| Length = 704 Score = 63.5 bits (153), Expect = 4e-10 Identities = 52/194 (26%), Positives = 87/194 (44%), Gaps = 5/194 (2%) Frame = +2 Query: 32 GKSDPFAVLYIRPLSAKTKK--SKTINNDLNPIWNE---HYEFVVEDSSTQHLTVKIYDD 196 G +DP+ L++ P ++K+ K +KT+ N NPIWNE ++ ED + L + + D+ Sbjct: 436 GLADPYVKLHLLPGASKSNKLRTKTLRNTRNPIWNETLVYHGITDEDMQRKTLRISVCDE 495 Query: 197 EGLQPSEIIGCARVDLSDIMPGKVKDVWLELVKDLEIQRDKKPRGQVHLELLYYPFDKQE 376 + +E IG R L + P + K+ + L + + ++R G LY Sbjct: 496 DKFGHNEFIGETRFSLKKLKPNQRKNFNICLERVIPMKR-AGTTGSARGMALY------- 547 Query: 377 GVSNPFASQIQLTSLEKVLKTESNGYDVNQRKNVITRGVLSVTVISAEDIPAMDVMGKAD 556 + +E++ E G + +G L V +I + AMD G +D Sbjct: 548 ----------EEEQVERIGDIEERGKILVSLMYSTQQGGLIVGIIRCVHLAAMDANGYSD 597 Query: 557 PFVVLYLKKGETKK 598 PFV L+LK KK Sbjct: 598 PFVKLWLKPDMGKK 611 Score = 31.2 bits (69), Expect = 2.4 Identities = 15/34 (44%), Positives = 21/34 (61%) Frame = +2 Query: 494 LSVTVISAEDIPAMDVMGKADPFVVLYLKKGETK 595 L T+I A+ + MD G ADP+V L+L G +K Sbjct: 419 LHCTIIKAKGLKPMDSNGLADPYVKLHLLPGASK 452
>DOC2B_HUMAN (Q14184) Double C2-like domain-containing protein beta (Doc2-beta)| Length = 412 Score = 63.2 bits (152), Expect = 6e-10 Identities = 53/194 (27%), Positives = 79/194 (40%), Gaps = 5/194 (2%) Frame = +2 Query: 32 GKSDPFAVLYIRPLSAKTKK--SKTINNDLNPIWNE---HYEFVVEDSSTQHLTVKIYDD 196 G +DP+ L++ P ++K K +KT+ N LNP WNE +Y ED + L + + D+ Sbjct: 160 GLADPYVKLHLLPGASKANKLRTKTLRNTLNPTWNETLTYYGITDEDMIRKTLRISVCDE 219 Query: 197 EGLQPSEIIGCARVDLSDIMPGKVKDVWLELVKDLEIQRDKKPRGQVHLELLYYPFDKQE 376 + + +E IG RV L + P K + L K L P DK E Sbjct: 220 DKFRHNEFIGETRVPLKKLKPNHTKTFNICLEKQL-------------------PVDKTE 260 Query: 377 GVSNPFASQIQLTSLEKVLKTESNGYDVNQRKNVITRGVLSVTVISAEDIPAMDVMGKAD 556 S E G + K + L V ++ + AMD G +D Sbjct: 261 DKS-----------------LEERGRILISLKYSSQKQGLLVGIVRCAHLAAMDANGYSD 303 Query: 557 PFVVLYLKKGETKK 598 P+V YL+ KK Sbjct: 304 PYVKTYLRPDVDKK 317 Score = 35.4 bits (80), Expect = 0.13 Identities = 24/69 (34%), Positives = 35/69 (50%), Gaps = 4/69 (5%) Frame = +2 Query: 32 GKSDPFAVLYIRPLSAKTKKSKTI--NNDLNPIWNEH--YEFVVEDSSTQHLTVKIYDDE 199 G SDP+ Y+RP K K KT LNP +NE YE D + + L V ++D + Sbjct: 300 GYSDPYVKTYLRPDVDKKSKHKTAVKKKTLNPEFNEEFCYEIKHGDLAKKSLEVTVWDYD 359 Query: 200 GLQPSEIIG 226 + ++ IG Sbjct: 360 IGKSNDFIG 368
>SYT1_CAEEL (P34693) Synaptotagmin-1 (Synaptotagmin I)| Length = 441 Score = 62.0 bits (149), Expect = 1e-09 Identities = 47/192 (24%), Positives = 78/192 (40%), Gaps = 2/192 (1%) Frame = +2 Query: 32 GKSDPFAVLYIRPLSAKTKKSKTINNDLNPIWNEHYEFVV--EDSSTQHLTVKIYDDEGL 205 G SDP+ LY+ P K ++K LNP++NE + F V + + + L IYD + Sbjct: 193 GTSDPYVKLYLLPEKKKKVETKVHRKTLNPVFNETFIFKVAFNEITAKTLVFAIYDFDRF 252 Query: 206 QPSEIIGCARVDLSDIMPGKVKDVWLELVKDLEIQRDKKPRGQVHLELLYYPFDKQEGVS 385 + IG + L I G V + W ++ + + +K G + L Y P Sbjct: 253 SKHDQIGQVLIPLGKIDLGAVIEEWKDIAPPPDDKEAEKSLGDICFSLRYVP-------- 304 Query: 386 NPFASQIQLTSLEKVLKTESNGYDVNQRKNVITRGVLSVTVISAEDIPAMDVMGKADPFV 565 T G L+V ++ A+++ MDV G +DP+V Sbjct: 305 --------------------------------TAGKLTVVILEAKNLKKMDVGGLSDPYV 332 Query: 566 VLYLKKGETKKK 601 + L +G + K Sbjct: 333 KIVLMQGGKRLK 344 Score = 45.8 bits (107), Expect = 9e-05 Identities = 24/42 (57%), Positives = 30/42 (71%), Gaps = 5/42 (11%) Frame = +2 Query: 485 RGVLSVTVISAEDIPAMDVMGKADPFVVLYL-----KKGETK 595 +G L+VTVI AED+P MD+ G +DP+V LYL KK ETK Sbjct: 173 QGQLTVTVIQAEDLPGMDMSGTSDPYVKLYLLPEKKKKVETK 214 Score = 30.8 bits (68), Expect = 3.1 Identities = 21/69 (30%), Positives = 32/69 (46%), Gaps = 4/69 (5%) Frame = +2 Query: 32 GKSDPFAVLYIRPLSAKTKKSKTINND--LNPIWNEHYEFVV--EDSSTQHLTVKIYDDE 199 G SDP+ + + + KK KT LNP +NE + F V E L + + D + Sbjct: 326 GLSDPYVKIVLMQGGKRLKKKKTSIKKCTLNPYYNESFSFEVPFEQIQKVSLMITVMDYD 385 Query: 200 GLQPSEIIG 226 L ++ IG Sbjct: 386 KLGSNDAIG 394
>RP3A_MOUSE (P47708) Rabphilin-3A (Exophilin-1)| Length = 681 Score = 60.5 bits (145), Expect = 4e-09 Identities = 50/194 (25%), Positives = 86/194 (44%), Gaps = 5/194 (2%) Frame = +2 Query: 32 GKSDPFAVLYIRPLSAKTKK--SKTINNDLNPIWNEHYEF---VVEDSSTQHLTVKIYDD 196 G +DP+ L++ P ++K+ K +KT+ N NP+WNE ++ ED + L + + D+ Sbjct: 413 GLADPYVKLHLLPGASKSNKLRTKTLRNTRNPVWNETLQYHGITEEDMQRKTLRISVCDE 472 Query: 197 EGLQPSEIIGCARVDLSDIMPGKVKDVWLELVKDLEIQRDKKPRGQVHLELLYYPFDKQE 376 + +E IG R L + + K+ + L + + ++R G LY Sbjct: 473 DKFGHNEFIGETRFSLKKLKANQRKNFNICLERVIPMKR-AGTTGSARGMALY------- 524 Query: 377 GVSNPFASQIQLTSLEKVLKTESNGYDVNQRKNVITRGVLSVTVISAEDIPAMDVMGKAD 556 + +E++ E G + +G L V +I + AMD G +D Sbjct: 525 ----------EEEQVERIGDIEERGKILVSLMYSTQQGGLIVGIIRCVHLAAMDANGYSD 574 Query: 557 PFVVLYLKKGETKK 598 PFV L+LK KK Sbjct: 575 PFVKLWLKPDMGKK 588 Score = 31.2 bits (69), Expect = 2.4 Identities = 15/34 (44%), Positives = 21/34 (61%) Frame = +2 Query: 494 LSVTVISAEDIPAMDVMGKADPFVVLYLKKGETK 595 L T+I A+ + MD G ADP+V L+L G +K Sbjct: 396 LQCTIIRAKGLKPMDSNGLADPYVKLHLLPGASK 429
>RP3A_RAT (P47709) Rabphilin-3A (Exophilin-1)| Length = 684 Score = 60.5 bits (145), Expect = 4e-09 Identities = 50/194 (25%), Positives = 86/194 (44%), Gaps = 5/194 (2%) Frame = +2 Query: 32 GKSDPFAVLYIRPLSAKTKK--SKTINNDLNPIWNEHYEF---VVEDSSTQHLTVKIYDD 196 G +DP+ L++ P ++K+ K +KT+ N NP+WNE ++ ED + L + + D+ Sbjct: 416 GLADPYVKLHLLPGASKSNKLRTKTLRNTRNPVWNETLQYHGITEEDMQRKTLRISVCDE 475 Query: 197 EGLQPSEIIGCARVDLSDIMPGKVKDVWLELVKDLEIQRDKKPRGQVHLELLYYPFDKQE 376 + +E IG R L + + K+ + L + + ++R G LY Sbjct: 476 DKFGHNEFIGETRFSLKKLKANQRKNFNICLERVIPMKR-AGTTGSARGMALY------- 527 Query: 377 GVSNPFASQIQLTSLEKVLKTESNGYDVNQRKNVITRGVLSVTVISAEDIPAMDVMGKAD 556 + +E++ E G + +G L V +I + AMD G +D Sbjct: 528 ----------EEEQVERIGDIEERGKILVSLMYSTQQGGLIVGIIRCVHLAAMDANGYSD 577 Query: 557 PFVVLYLKKGETKK 598 PFV L+LK KK Sbjct: 578 PFVKLWLKPDMGKK 591 Score = 31.2 bits (69), Expect = 2.4 Identities = 15/34 (44%), Positives = 21/34 (61%) Frame = +2 Query: 494 LSVTVISAEDIPAMDVMGKADPFVVLYLKKGETK 595 L T+I A+ + MD G ADP+V L+L G +K Sbjct: 399 LQCTIIRAKGLKPMDSNGLADPYVKLHLLPGASK 432
>DOC2A_HUMAN (Q14183) Double C2-like domain-containing protein alpha| (Doc2-alpha) (Doc2) Length = 400 Score = 59.7 bits (143), Expect = 6e-09 Identities = 51/194 (26%), Positives = 88/194 (45%), Gaps = 5/194 (2%) Frame = +2 Query: 32 GKSDPFAVLYIRPLSAKTKK--SKTINNDLNPIWNEH--YEFVVEDSSTQH-LTVKIYDD 196 G +DP+ L++ P + K K +KT N LNP+WNE Y + +D T L + + D+ Sbjct: 123 GLADPYVKLHLLPGACKANKLKTKTQRNTLNPVWNEDLTYSGITDDDITHKVLRIAVCDE 182 Query: 197 EGLQPSEIIGCARVDLSDIMPGKVKDVWLELVKDLEIQRDKKPRGQVHLELLYYPFDKQE 376 + L +E IG RV L + P + K + L + + + + Sbjct: 183 DKLSHNEFIGEIRVPLRRLKPSQKKHFNICLERQVPLASPSSMSAALR------------ 230 Query: 377 GVSNPFASQIQLTSLEKVLKTESNGYDVNQRKNVITRGVLSVTVISAEDIPAMDVMGKAD 556 G+S + +++ + L E ++ + RG+L V ++ + AMDV G +D Sbjct: 231 GISC-YLKELEQAEQGQGLLEERGRILLSLSYSSRRRGLL-VGILRCAHLAAMDVNGYSD 288 Query: 557 PFVVLYLKKGETKK 598 P+V YL+ KK Sbjct: 289 PYVKTYLRPDVDKK 302 Score = 38.1 bits (87), Expect = 0.020 Identities = 28/92 (30%), Positives = 47/92 (51%), Gaps = 4/92 (4%) Frame = +2 Query: 32 GKSDPFAVLYIRPLSAKTKKSKTI--NNDLNPIWNEHYEFVVEDS--STQHLTVKIYDDE 199 G SDP+ Y+RP K K KT LNP +NE + + +E S +T+ L V ++D + Sbjct: 285 GYSDPYVKTYLRPDVDKKSKHKTCVKKKTLNPEFNEEFFYEIELSTLATKTLEVTVWDYD 344 Query: 200 GLQPSEIIGCARVDLSDIMPGKVKDVWLELVK 295 + ++ IG V L G+ + W + ++ Sbjct: 345 IGKSNDFIG--GVSLGPGARGEARKHWSDCLQ 374
>SY61_DISOM (P24505) Synaptotagmin A (Synaptic vesicle protein O-p65-A)| Length = 427 Score = 59.3 bits (142), Expect = 8e-09 Identities = 46/193 (23%), Positives = 85/193 (44%), Gaps = 3/193 (1%) Frame = +2 Query: 32 GKSDPFAVLYIRPLSAKTKKSKTINNDLNPIWNEHYEFVVEDSST--QHLTVKIYDDEGL 205 G SDP+ +++ P K ++K LNP++NE + F + S + L + +YD + Sbjct: 181 GTSDPYVKVFVLPDKKKKYETKVHRKTLNPVFNESFIFKIPYSELGGKTLVMAVYDFDRF 240 Query: 206 QPSEIIGCARVDLSDIMPGKVKDVWLELVKDLEIQRDKKPRGQVHLELLYYPFDKQEGVS 385 ++IG A+V ++ + G V + W +L + +++K G + L Y P Sbjct: 241 SKHDVIGEAKVPMNTVDFGHVTEEWRDLQGAEKEEQEK--LGDICFSLRYVP-------- 290 Query: 386 NPFASQIQLTSLEKVLKTESNGYDVNQRKNVITRGVLSVTVISAEDIPAMDVMGKADPFV 565 T G L+V ++ A+++ MDV G +DP+V Sbjct: 291 --------------------------------TAGKLTVVILEAKNLKKMDVGGLSDPYV 318 Query: 566 VLYL-KKGETKKK 601 ++L + G+ KK Sbjct: 319 KIHLMQNGKRLKK 331 Score = 35.4 bits (80), Expect = 0.13 Identities = 21/69 (30%), Positives = 34/69 (49%), Gaps = 4/69 (5%) Frame = +2 Query: 32 GKSDPFAVLYIRPLSAKTKKSKTI--NNDLNPIWNEHYEFVV--EDSSTQHLTVKIYDDE 199 G SDP+ +++ + KK KT N LNP +NE + F V E + V + D + Sbjct: 312 GLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQVVVTVLDYD 371 Query: 200 GLQPSEIIG 226 + ++ IG Sbjct: 372 KIGKNDAIG 380 Score = 32.7 bits (73), Expect = 0.82 Identities = 17/39 (43%), Positives = 26/39 (66%), Gaps = 5/39 (12%) Frame = +2 Query: 494 LSVTVISAEDIPAMDVMGKADPFVVLYL-----KKGETK 595 L V +I A ++PA+DV G +DP+V +++ KK ETK Sbjct: 164 LIVGIIQAAELPALDVGGTSDPYVKVFVLPDKKKKYETK 202
>DOC2A_MOUSE (Q7TNF0) Double C2-like domain-containing protein alpha| (Doc2-alpha) Length = 405 Score = 58.9 bits (141), Expect = 1e-08 Identities = 53/205 (25%), Positives = 86/205 (41%), Gaps = 16/205 (7%) Frame = +2 Query: 32 GKSDPFAVLYIRPLSAKTKK--SKTINNDLNPIWNEH--YEFVVEDSSTQH-LTVKIYDD 196 G +DP+ L++ P + K K +KT N LNP+WNE Y + +D T L + + D+ Sbjct: 128 GLADPYVKLHLLPGACKANKLKTKTQRNTLNPVWNEELTYSGITDDDITHKVLRISVCDE 187 Query: 197 EGLQPSEIIGCARVDLSDIMPGKVKDVWLELVKDLEIQRDKKPRGQVHLELLYYPFDKQE 376 + L +E IG RV L + P + K H + ++Q Sbjct: 188 DKLSHNEFIGEIRVPLRRLKPSQKK----------------------HFNIC---LERQV 222 Query: 377 GVSNPFASQIQLTSLEKVLK----TESNGYDVNQRKNVIT-------RGVLSVTVISAED 523 + +P + L + LK E + +R ++ R L V ++ Sbjct: 223 PLPSPSSMSAALRGISCYLKELEQAEQGPGLLEERGRILLSLSYSSRRHGLLVGIVRCAH 282 Query: 524 IPAMDVMGKADPFVVLYLKKGETKK 598 + AMDV G +DP+V YL+ KK Sbjct: 283 LAAMDVNGYSDPYVKTYLRPDVDKK 307 Score = 37.4 bits (85), Expect = 0.033 Identities = 24/69 (34%), Positives = 38/69 (55%), Gaps = 4/69 (5%) Frame = +2 Query: 32 GKSDPFAVLYIRPLSAKTKKSKTI--NNDLNPIWNEHYEFVVEDS--STQHLTVKIYDDE 199 G SDP+ Y+RP K K KT LNP +NE + + +E S +T+ L V ++D + Sbjct: 290 GYSDPYVKTYLRPDVDKKSKHKTCVKKKTLNPEFNEEFFYEIELSTLATKTLEVTVWDYD 349 Query: 200 GLQPSEIIG 226 + ++ IG Sbjct: 350 IGKSNDFIG 358
>SYT1_RAT (P21707) Synaptotagmin-1 (Synaptotagmin I) (SytI) (p65)| Length = 421 Score = 58.9 bits (141), Expect = 1e-08 Identities = 47/193 (24%), Positives = 84/193 (43%), Gaps = 3/193 (1%) Frame = +2 Query: 32 GKSDPFAVLYIRPLSAKTKKSKTINNDLNPIWNEHYEFVVEDSST--QHLTVKIYDDEGL 205 G SDP+ +++ P K ++K LNP++NE + F V S + L + +YD + Sbjct: 175 GTSDPYVKVFLLPDKKKKFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRF 234 Query: 206 QPSEIIGCARVDLSDIMPGKVKDVWLELVKDLEIQRDKKPRGQVHLELLYYPFDKQEGVS 385 +IIG +V ++ + G V + W +L + +++K G + L Y P Sbjct: 235 SKHDIIGEFKVPMNTVDFGHVTEEWRDLQSAEKEEQEK--LGDICFSLRYVP-------- 284 Query: 386 NPFASQIQLTSLEKVLKTESNGYDVNQRKNVITRGVLSVTVISAEDIPAMDVMGKADPFV 565 T G L+V ++ A+++ MDV G +DP+V Sbjct: 285 --------------------------------TAGKLTVVILEAKNLKKMDVGGLSDPYV 312 Query: 566 VLYL-KKGETKKK 601 ++L + G+ KK Sbjct: 313 KIHLMQNGKRLKK 325 Score = 35.4 bits (80), Expect = 0.13 Identities = 21/69 (30%), Positives = 34/69 (49%), Gaps = 4/69 (5%) Frame = +2 Query: 32 GKSDPFAVLYIRPLSAKTKKSKTI--NNDLNPIWNEHYEFVV--EDSSTQHLTVKIYDDE 199 G SDP+ +++ + KK KT N LNP +NE + F V E + V + D + Sbjct: 306 GLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQVVVTVLDYD 365 Query: 200 GLQPSEIIG 226 + ++ IG Sbjct: 366 KIGKNDAIG 374 Score = 32.7 bits (73), Expect = 0.82 Identities = 17/39 (43%), Positives = 26/39 (66%), Gaps = 5/39 (12%) Frame = +2 Query: 494 LSVTVISAEDIPAMDVMGKADPFVVLYL-----KKGETK 595 L V +I A ++PA+D+ G +DP+V ++L KK ETK Sbjct: 158 LLVGIIQAAELPALDMGGTSDPYVKVFLLPDKKKKFETK 196
>SYT1_MOUSE (P46096) Synaptotagmin-1 (Synaptotagmin I) (SytI) (p65)| Length = 421 Score = 58.9 bits (141), Expect = 1e-08 Identities = 47/193 (24%), Positives = 84/193 (43%), Gaps = 3/193 (1%) Frame = +2 Query: 32 GKSDPFAVLYIRPLSAKTKKSKTINNDLNPIWNEHYEFVVEDSST--QHLTVKIYDDEGL 205 G SDP+ +++ P K ++K LNP++NE + F V S + L + +YD + Sbjct: 175 GTSDPYVKVFLLPDKKKKFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRF 234 Query: 206 QPSEIIGCARVDLSDIMPGKVKDVWLELVKDLEIQRDKKPRGQVHLELLYYPFDKQEGVS 385 +IIG +V ++ + G V + W +L + +++K G + L Y P Sbjct: 235 SKHDIIGEFKVPMNTVDFGHVTEEWRDLQSAEKEEQEK--LGDICFSLRYVP-------- 284 Query: 386 NPFASQIQLTSLEKVLKTESNGYDVNQRKNVITRGVLSVTVISAEDIPAMDVMGKADPFV 565 T G L+V ++ A+++ MDV G +DP+V Sbjct: 285 --------------------------------TAGKLTVVILEAKNLKKMDVGGLSDPYV 312 Query: 566 VLYL-KKGETKKK 601 ++L + G+ KK Sbjct: 313 KIHLMQNGKRLKK 325 Score = 35.4 bits (80), Expect = 0.13 Identities = 21/69 (30%), Positives = 34/69 (49%), Gaps = 4/69 (5%) Frame = +2 Query: 32 GKSDPFAVLYIRPLSAKTKKSKTI--NNDLNPIWNEHYEFVV--EDSSTQHLTVKIYDDE 199 G SDP+ +++ + KK KT N LNP +NE + F V E + V + D + Sbjct: 306 GLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQVVVTVLDYD 365 Query: 200 GLQPSEIIG 226 + ++ IG Sbjct: 366 KIGKNDAIG 374 Score = 32.7 bits (73), Expect = 0.82 Identities = 17/39 (43%), Positives = 26/39 (66%), Gaps = 5/39 (12%) Frame = +2 Query: 494 LSVTVISAEDIPAMDVMGKADPFVVLYL-----KKGETK 595 L V +I A ++PA+D+ G +DP+V ++L KK ETK Sbjct: 158 LLVGIIQAAELPALDMGGTSDPYVKVFLLPDKKKKFETK 196
>SYT1_PONPY (Q5R4J5) Synaptotagmin-1 (Synaptotagmin I) (SytI)| Length = 419 Score = 58.9 bits (141), Expect = 1e-08 Identities = 47/193 (24%), Positives = 84/193 (43%), Gaps = 3/193 (1%) Frame = +2 Query: 32 GKSDPFAVLYIRPLSAKTKKSKTINNDLNPIWNEHYEFVVEDSST--QHLTVKIYDDEGL 205 G SDP+ +++ P K ++K LNP++NE + F V S + L + +YD + Sbjct: 173 GTSDPYVKVFLLPDKKKKFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRF 232 Query: 206 QPSEIIGCARVDLSDIMPGKVKDVWLELVKDLEIQRDKKPRGQVHLELLYYPFDKQEGVS 385 +IIG +V ++ + G V + W +L + +++K G + L Y P Sbjct: 233 SKHDIIGEFKVPMNTVDFGHVTEEWRDLQSAEKEEQEK--LGDICFSLRYVP-------- 282 Query: 386 NPFASQIQLTSLEKVLKTESNGYDVNQRKNVITRGVLSVTVISAEDIPAMDVMGKADPFV 565 T G L+V ++ A+++ MDV G +DP+V Sbjct: 283 --------------------------------TAGKLTVVILEAKNLKKMDVGGLSDPYV 310 Query: 566 VLYL-KKGETKKK 601 ++L + G+ KK Sbjct: 311 KIHLMQNGKRLKK 323 Score = 33.9 bits (76), Expect = 0.37 Identities = 20/69 (28%), Positives = 34/69 (49%), Gaps = 4/69 (5%) Frame = +2 Query: 32 GKSDPFAVLYIRPLSAKTKKSKTI--NNDLNPIWNEHYEFVV--EDSSTQHLTVKIYDDE 199 G SDP+ +++ + KK +T N LNP +NE + F V E + V + D + Sbjct: 304 GLSDPYVKIHLMQNGKRLKKKETTIKKNTLNPYYNESFSFEVPFEQIQKVQVVVTVLDYD 363 Query: 200 GLQPSEIIG 226 + ++ IG Sbjct: 364 KIGKNDAIG 372 Score = 32.7 bits (73), Expect = 0.82 Identities = 17/39 (43%), Positives = 26/39 (66%), Gaps = 5/39 (12%) Frame = +2 Query: 494 LSVTVISAEDIPAMDVMGKADPFVVLYL-----KKGETK 595 L V +I A ++PA+D+ G +DP+V ++L KK ETK Sbjct: 156 LLVGIIQAAELPALDMGGTSDPYVKVFLLPDKKKKFETK 194
>SYT1_MACFA (Q60HC0) Synaptotagmin-1 (Synaptotagmin I) (SytI)| Length = 419 Score = 58.9 bits (141), Expect = 1e-08 Identities = 47/193 (24%), Positives = 84/193 (43%), Gaps = 3/193 (1%) Frame = +2 Query: 32 GKSDPFAVLYIRPLSAKTKKSKTINNDLNPIWNEHYEFVVEDSST--QHLTVKIYDDEGL 205 G SDP+ +++ P K ++K LNP++NE + F V S + L + +YD + Sbjct: 173 GTSDPYVKVFLLPDKKKKFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRF 232 Query: 206 QPSEIIGCARVDLSDIMPGKVKDVWLELVKDLEIQRDKKPRGQVHLELLYYPFDKQEGVS 385 +IIG +V ++ + G V + W +L + +++K G + L Y P Sbjct: 233 SKHDIIGEFKVPMNTVDFGHVTEEWRDLQSAEKEEQEK--LGDICFSLRYVP-------- 282 Query: 386 NPFASQIQLTSLEKVLKTESNGYDVNQRKNVITRGVLSVTVISAEDIPAMDVMGKADPFV 565 T G L+V ++ A+++ MDV G +DP+V Sbjct: 283 --------------------------------TAGKLTVVILEAKNLKKMDVGGLSDPYV 310 Query: 566 VLYL-KKGETKKK 601 ++L + G+ KK Sbjct: 311 KIHLMQNGKRLKK 323 Score = 35.4 bits (80), Expect = 0.13 Identities = 21/69 (30%), Positives = 34/69 (49%), Gaps = 4/69 (5%) Frame = +2 Query: 32 GKSDPFAVLYIRPLSAKTKKSKTI--NNDLNPIWNEHYEFVV--EDSSTQHLTVKIYDDE 199 G SDP+ +++ + KK KT N LNP +NE + F V E + V + D + Sbjct: 304 GLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQVVVTVLDYD 363 Query: 200 GLQPSEIIG 226 + ++ IG Sbjct: 364 KIGKNDAIG 372 Score = 32.7 bits (73), Expect = 0.82 Identities = 17/39 (43%), Positives = 26/39 (66%), Gaps = 5/39 (12%) Frame = +2 Query: 494 LSVTVISAEDIPAMDVMGKADPFVVLYL-----KKGETK 595 L V +I A ++PA+D+ G +DP+V ++L KK ETK Sbjct: 156 LLVGIIQAAELPALDMGGTSDPYVKVFLLPDKKKKFETK 194
>SYT1_HUMAN (P21579) Synaptotagmin-1 (Synaptotagmin I) (SytI) (p65)| Length = 422 Score = 58.9 bits (141), Expect = 1e-08 Identities = 47/193 (24%), Positives = 84/193 (43%), Gaps = 3/193 (1%) Frame = +2 Query: 32 GKSDPFAVLYIRPLSAKTKKSKTINNDLNPIWNEHYEFVVEDSST--QHLTVKIYDDEGL 205 G SDP+ +++ P K ++K LNP++NE + F V S + L + +YD + Sbjct: 176 GTSDPYVKVFLLPDKKKKFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRF 235 Query: 206 QPSEIIGCARVDLSDIMPGKVKDVWLELVKDLEIQRDKKPRGQVHLELLYYPFDKQEGVS 385 +IIG +V ++ + G V + W +L + +++K G + L Y P Sbjct: 236 SKHDIIGEFKVPMNTVDFGHVTEEWRDLQSAEKEEQEK--LGDICFSLRYVP-------- 285 Query: 386 NPFASQIQLTSLEKVLKTESNGYDVNQRKNVITRGVLSVTVISAEDIPAMDVMGKADPFV 565 T G L+V ++ A+++ MDV G +DP+V Sbjct: 286 --------------------------------TAGKLTVVILEAKNLKKMDVGGLSDPYV 313 Query: 566 VLYL-KKGETKKK 601 ++L + G+ KK Sbjct: 314 KIHLMQNGKRLKK 326 Score = 35.4 bits (80), Expect = 0.13 Identities = 21/69 (30%), Positives = 34/69 (49%), Gaps = 4/69 (5%) Frame = +2 Query: 32 GKSDPFAVLYIRPLSAKTKKSKTI--NNDLNPIWNEHYEFVV--EDSSTQHLTVKIYDDE 199 G SDP+ +++ + KK KT N LNP +NE + F V E + V + D + Sbjct: 307 GLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQVVVTVLDYD 366 Query: 200 GLQPSEIIG 226 + ++ IG Sbjct: 367 KIGKNDAIG 375 Score = 32.7 bits (73), Expect = 0.82 Identities = 17/39 (43%), Positives = 26/39 (66%), Gaps = 5/39 (12%) Frame = +2 Query: 494 LSVTVISAEDIPAMDVMGKADPFVVLYL-----KKGETK 595 L V +I A ++PA+D+ G +DP+V ++L KK ETK Sbjct: 159 LLVGIIQAAELPALDMGGTSDPYVKVFLLPDKKKKFETK 197
>SYT1_CHICK (P47191) Synaptotagmin-1 (Synaptotagmin I) (SytI) (p65)| Length = 424 Score = 58.9 bits (141), Expect = 1e-08 Identities = 47/193 (24%), Positives = 84/193 (43%), Gaps = 3/193 (1%) Frame = +2 Query: 32 GKSDPFAVLYIRPLSAKTKKSKTINNDLNPIWNEHYEFVVEDSST--QHLTVKIYDDEGL 205 G SDP+ +++ P K ++K LNP++NE + F V S + L + +YD + Sbjct: 178 GTSDPYVKVFLLPDKKKKYETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRF 237 Query: 206 QPSEIIGCARVDLSDIMPGKVKDVWLELVKDLEIQRDKKPRGQVHLELLYYPFDKQEGVS 385 +IIG +V ++ + G V + W +L + +++K G + L Y P Sbjct: 238 SKHDIIGEYKVAMNTVDFGHVTEEWRDLQSAEKEEQEK--LGDICFSLRYVP-------- 287 Query: 386 NPFASQIQLTSLEKVLKTESNGYDVNQRKNVITRGVLSVTVISAEDIPAMDVMGKADPFV 565 T G L+V ++ A+++ MDV G +DP+V Sbjct: 288 --------------------------------TAGKLTVVILEAKNLKKMDVGGLSDPYV 315 Query: 566 VLYL-KKGETKKK 601 ++L + G+ KK Sbjct: 316 KIHLMQNGKRLKK 328 Score = 35.8 bits (81), Expect = 0.097 Identities = 21/69 (30%), Positives = 34/69 (49%), Gaps = 4/69 (5%) Frame = +2 Query: 32 GKSDPFAVLYIRPLSAKTKKSKTI--NNDLNPIWNEHYEFVV--EDSSTQHLTVKIYDDE 199 G SDP+ +++ + KK KT N LNP +NE + F V E + V + D + Sbjct: 309 GLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQIVVTVLDYD 368 Query: 200 GLQPSEIIG 226 + ++ IG Sbjct: 369 KIGKNDAIG 377 Score = 32.7 bits (73), Expect = 0.82 Identities = 17/39 (43%), Positives = 26/39 (66%), Gaps = 5/39 (12%) Frame = +2 Query: 494 LSVTVISAEDIPAMDVMGKADPFVVLYL-----KKGETK 595 L V +I A ++PA+D+ G +DP+V ++L KK ETK Sbjct: 161 LLVGIIQAAELPALDMGGTSDPYVKVFLLPDKKKKYETK 199
>SYT1_BOVIN (P48018) Synaptotagmin-1 (Synaptotagmin I) (SytI) (p65)| Length = 422 Score = 58.9 bits (141), Expect = 1e-08 Identities = 47/193 (24%), Positives = 84/193 (43%), Gaps = 3/193 (1%) Frame = +2 Query: 32 GKSDPFAVLYIRPLSAKTKKSKTINNDLNPIWNEHYEFVVEDSST--QHLTVKIYDDEGL 205 G SDP+ +++ P K ++K LNP++NE + F V S + L + +YD + Sbjct: 176 GTSDPYVKVFLLPDKKKKFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRF 235 Query: 206 QPSEIIGCARVDLSDIMPGKVKDVWLELVKDLEIQRDKKPRGQVHLELLYYPFDKQEGVS 385 +IIG +V ++ + G V + W +L + +++K G + L Y P Sbjct: 236 SKHDIIGEFKVPMNTVDFGHVTEEWRDLQSAEKEEQEK--LGDICFSLRYVP-------- 285 Query: 386 NPFASQIQLTSLEKVLKTESNGYDVNQRKNVITRGVLSVTVISAEDIPAMDVMGKADPFV 565 T G L+V ++ A+++ MDV G +DP+V Sbjct: 286 --------------------------------TAGKLTVVILEAKNLKKMDVGGLSDPYV 313 Query: 566 VLYL-KKGETKKK 601 ++L + G+ KK Sbjct: 314 KIHLMQNGKRLKK 326 Score = 35.4 bits (80), Expect = 0.13 Identities = 21/69 (30%), Positives = 34/69 (49%), Gaps = 4/69 (5%) Frame = +2 Query: 32 GKSDPFAVLYIRPLSAKTKKSKTI--NNDLNPIWNEHYEFVV--EDSSTQHLTVKIYDDE 199 G SDP+ +++ + KK KT N LNP +NE + F V E + V + D + Sbjct: 307 GLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQVVVTVLDYD 366 Query: 200 GLQPSEIIG 226 + ++ IG Sbjct: 367 KIGKNDAIG 375 Score = 32.7 bits (73), Expect = 0.82 Identities = 17/39 (43%), Positives = 26/39 (66%), Gaps = 5/39 (12%) Frame = +2 Query: 494 LSVTVISAEDIPAMDVMGKADPFVVLYL-----KKGETK 595 L V +I A ++PA+D+ G +DP+V ++L KK ETK Sbjct: 159 LLVGIIQAAELPALDMGGTSDPYVKVFLLPDKKKKFETK 197
>DOC2A_RAT (P70611) Double C2-like domain-containing protein alpha| (Doc2-alpha) Length = 403 Score = 58.9 bits (141), Expect = 1e-08 Identities = 53/205 (25%), Positives = 86/205 (41%), Gaps = 16/205 (7%) Frame = +2 Query: 32 GKSDPFAVLYIRPLSAKTKK--SKTINNDLNPIWNEH--YEFVVEDSSTQH-LTVKIYDD 196 G +DP+ L++ P + K K +KT N LNP+WNE Y + +D T L + + D+ Sbjct: 126 GLADPYVKLHLLPGACKANKLKTKTQRNTLNPVWNEELTYSGITDDDITHKVLRISVCDE 185 Query: 197 EGLQPSEIIGCARVDLSDIMPGKVKDVWLELVKDLEIQRDKKPRGQVHLELLYYPFDKQE 376 + L +E IG RV L + P + K H + ++Q Sbjct: 186 DKLSHNEFIGEIRVPLRRLKPSQKK----------------------HFNIC---LERQV 220 Query: 377 GVSNPFASQIQLTSLEKVLK----TESNGYDVNQRKNVIT-------RGVLSVTVISAED 523 + +P + L + LK E + +R ++ R L V ++ Sbjct: 221 PLPSPSSMSAALRGISCYLKELEQAEQGPGLLEERGRILLSLSYSSRRHGLLVGIVRCAH 280 Query: 524 IPAMDVMGKADPFVVLYLKKGETKK 598 + AMDV G +DP+V YL+ KK Sbjct: 281 LAAMDVNGYSDPYVKTYLRPDVDKK 305 Score = 37.0 bits (84), Expect = 0.044 Identities = 24/69 (34%), Positives = 36/69 (52%), Gaps = 4/69 (5%) Frame = +2 Query: 32 GKSDPFAVLYIRPLSAKTKKSKTI--NNDLNPIWNEH--YEFVVEDSSTQHLTVKIYDDE 199 G SDP+ Y+RP K K KT LNP +NE YE + +T+ L V ++D + Sbjct: 288 GYSDPYVKTYLRPDVDKKSKHKTCVKKKTLNPEFNEEFFYEMELSTLATKTLEVTVWDYD 347 Query: 200 GLQPSEIIG 226 + ++ IG Sbjct: 348 IGKSNDFIG 356
>SYT5_RAT (P47861) Synaptotagmin-5 (Synaptotagmin V) (SytV) (Synaptotagmin| IX) Length = 386 Score = 57.8 bits (138), Expect = 2e-08 Identities = 46/192 (23%), Positives = 80/192 (41%), Gaps = 2/192 (1%) Frame = +2 Query: 26 LVGKSDPFAVLYIRPLSAKTKKSKTINNDLNPIWNEHYEFVVE--DSSTQHLTVKIYDDE 199 L G SDP+ +Y+ P + ++K LNP + E + F V + + L + +YD + Sbjct: 140 LGGSSDPYVSVYLLPDKRRRHETKVHRQTLNPHFGETFAFKVPYVELGGRVLVMAVYDFD 199 Query: 200 GLQPSEIIGCARVDLSDIMPGKVKDVWLELVKDLEIQRDKKPRGQVHLELLYYPFDKQEG 379 ++ IG RV +S + G+ W EL + + +++ G + L Y P Sbjct: 200 RFSRNDAIGEVRVPMSSVNLGRPVQAWREL--QVAPKEEQEKLGDICFSLRYVP------ 251 Query: 380 VSNPFASQIQLTSLEKVLKTESNGYDVNQRKNVITRGVLSVTVISAEDIPAMDVMGKADP 559 T G L+V V+ A+++ MDV G +DP Sbjct: 252 ----------------------------------TAGKLTVIVLEAKNLKKMDVGGLSDP 277 Query: 560 FVVLYLKKGETK 595 +V ++L +G K Sbjct: 278 YVKVHLLQGGKK 289 Score = 37.7 bits (86), Expect = 0.026 Identities = 30/107 (28%), Positives = 49/107 (45%), Gaps = 4/107 (3%) Frame = +2 Query: 32 GKSDPFAVLYIRPLSAKTKKSKTI--NNDLNPIWNEHYEFVVEDSSTQHLTVK--IYDDE 199 G SDP+ +++ K +K KT N LNP +NE + F V Q + V+ + D + Sbjct: 273 GLSDPYVKVHLLQGGKKVRKKKTTIKKNTLNPYYNEAFSFEVPCDQVQKVQVELTVLDYD 332 Query: 200 GLQPSEIIGCARVDLSDIMPGKVKDVWLELVKDLEIQRDKKPRGQVH 340 L +E IG RV + + G W ++ + ++P Q H Sbjct: 333 KLGKNEAIG--RVAVGTAVGGAGLRHWADM-----LANPRRPIAQWH 372 Score = 31.6 bits (70), Expect = 1.8 Identities = 16/41 (39%), Positives = 26/41 (63%), Gaps = 5/41 (12%) Frame = +2 Query: 488 GVLSVTVISAEDIPAMDVMGKADPFVVLYL-----KKGETK 595 G L V ++ AE + A+D+ G +DP+V +YL ++ ETK Sbjct: 123 GQLLVGILQAEGLAALDLGGSSDPYVSVYLLPDKRRRHETK 163
>SYT5_MOUSE (Q9R0N5) Synaptotagmin-5 (Synaptotagmin V) (SytV) (Synaptotagmin| IX) Length = 386 Score = 57.8 bits (138), Expect = 2e-08 Identities = 46/192 (23%), Positives = 80/192 (41%), Gaps = 2/192 (1%) Frame = +2 Query: 26 LVGKSDPFAVLYIRPLSAKTKKSKTINNDLNPIWNEHYEFVVE--DSSTQHLTVKIYDDE 199 L G SDP+ +Y+ P + ++K LNP + E + F V + + L + +YD + Sbjct: 140 LGGSSDPYVSVYLLPDKRRRHETKVHRQTLNPHFGETFAFKVPYVELGGRVLVMAVYDFD 199 Query: 200 GLQPSEIIGCARVDLSDIMPGKVKDVWLELVKDLEIQRDKKPRGQVHLELLYYPFDKQEG 379 ++ IG RV +S + G+ W EL + + +++ G + L Y P Sbjct: 200 RFSRNDAIGEVRVPMSSVNLGRPVQAWREL--QVAPKEEQEKLGDICFSLRYVP------ 251 Query: 380 VSNPFASQIQLTSLEKVLKTESNGYDVNQRKNVITRGVLSVTVISAEDIPAMDVMGKADP 559 T G L+V V+ A+++ MDV G +DP Sbjct: 252 ----------------------------------TAGKLTVIVLEAKNLKKMDVGGLSDP 277 Query: 560 FVVLYLKKGETK 595 +V ++L +G K Sbjct: 278 YVKVHLLQGGKK 289 Score = 37.4 bits (85), Expect = 0.033 Identities = 30/107 (28%), Positives = 49/107 (45%), Gaps = 4/107 (3%) Frame = +2 Query: 32 GKSDPFAVLYIRPLSAKTKKSKTI--NNDLNPIWNEHYEFVVEDSSTQHLTVK--IYDDE 199 G SDP+ +++ K +K KT N LNP +NE + F V Q + V+ + D + Sbjct: 273 GLSDPYVKVHLLQGGKKVRKKKTTIKKNTLNPYYNEAFSFEVPCDQVQKVQVELTVLDYD 332 Query: 200 GLQPSEIIGCARVDLSDIMPGKVKDVWLELVKDLEIQRDKKPRGQVH 340 L +E IG RV + + G W ++ + ++P Q H Sbjct: 333 KLGKNEAIG--RVAVGAAVGGAGLRHWADM-----LANPRRPIAQWH 372 Score = 30.4 bits (67), Expect = 4.1 Identities = 15/41 (36%), Positives = 26/41 (63%), Gaps = 5/41 (12%) Frame = +2 Query: 488 GVLSVTVISAEDIPAMDVMGKADPFVVLYL-----KKGETK 595 G L V ++ A+ + A+D+ G +DP+V +YL ++ ETK Sbjct: 123 GQLLVGILQAQGLAALDLGGSSDPYVSVYLLPDKRRRHETK 163
>SYT5_HUMAN (O00445) Synaptotagmin-5 (Synaptotagmin V) (SytV)| Length = 386 Score = 55.8 bits (133), Expect = 9e-08 Identities = 46/192 (23%), Positives = 79/192 (41%), Gaps = 2/192 (1%) Frame = +2 Query: 26 LVGKSDPFAVLYIRPLSAKTKKSKTINNDLNPIWNEHYEFVVE--DSSTQHLTVKIYDDE 199 L G SDP+ +Y+ P + ++K LNP + E + F V + + L + +YD + Sbjct: 140 LGGSSDPYVRVYLLPDKRRRYETKVHRQTLNPHFGETFAFKVPYVELGGRVLVMAVYDFD 199 Query: 200 GLQPSEIIGCARVDLSDIMPGKVKDVWLELVKDLEIQRDKKPRGQVHLELLYYPFDKQEG 379 ++ IG RV +S + G+ W EL + +++ G + L Y P Sbjct: 200 RFSRNDAIGEVRVPMSSVDLGRPVQAWREL--QAAPREEQEKLGDICFSLRYVP------ 251 Query: 380 VSNPFASQIQLTSLEKVLKTESNGYDVNQRKNVITRGVLSVTVISAEDIPAMDVMGKADP 559 T G L+V V+ A+++ MDV G +DP Sbjct: 252 ----------------------------------TAGKLTVIVLEAKNLKKMDVGGLSDP 277 Query: 560 FVVLYLKKGETK 595 +V ++L +G K Sbjct: 278 YVKVHLLQGGKK 289 Score = 36.6 bits (83), Expect = 0.057 Identities = 23/69 (33%), Positives = 35/69 (50%), Gaps = 4/69 (5%) Frame = +2 Query: 32 GKSDPFAVLYIRPLSAKTKKSKTI--NNDLNPIWNEHYEFVVEDSSTQHLTVK--IYDDE 199 G SDP+ +++ K +K KT N LNP +NE + F V Q + V+ + D + Sbjct: 273 GLSDPYVKVHLLQGGKKVRKKKTTIKKNTLNPYYNEAFSFEVPCDQVQKVQVELTVLDYD 332 Query: 200 GLQPSEIIG 226 L +E IG Sbjct: 333 KLGKNEAIG 341
>SYT2_MOUSE (P46097) Synaptotagmin-2 (Synaptotagmin II) (SytII)| Length = 422 Score = 55.5 bits (132), Expect = 1e-07 Identities = 47/195 (24%), Positives = 85/195 (43%), Gaps = 5/195 (2%) Frame = +2 Query: 32 GKSDPFAVLYIRPLSAKTKKSKTINNDLNPIWNEHYEFVV--EDSSTQHLTVKIYDDEGL 205 G SDP+ +++ P K ++K LNP +NE + F V ++ + + L + IYD + Sbjct: 176 GTSDPYVKVFLLPDKKKKYETKVHRKTLNPAFNETFTFKVPYQELAGKTLVMAIYDFDRF 235 Query: 206 QPSEIIGCARVDLSDIMPGKVKDVWLELVKDLEIQRDKKPR--GQVHLELLYYPFDKQEG 379 +IIG +V ++ + G+ + W +DL+ ++P G + L Y P Sbjct: 236 SKHDIIGEVKVPMNTVDLGQPIEEW----RDLQGGEKEEPEKLGDICTSLRYVP------ 285 Query: 380 VSNPFASQIQLTSLEKVLKTESNGYDVNQRKNVITRGVLSVTVISAEDIPAMDVMGKADP 559 T G L+V ++ A+++ MDV G +DP Sbjct: 286 ----------------------------------TAGKLTVCILEAKNLKKMDVGGLSDP 311 Query: 560 FVVLYL-KKGETKKK 601 +V ++L + G+ KK Sbjct: 312 YVKIHLMQNGKRLKK 326 Score = 34.3 bits (77), Expect = 0.28 Identities = 21/69 (30%), Positives = 33/69 (47%), Gaps = 4/69 (5%) Frame = +2 Query: 32 GKSDPFAVLYIRPLSAKTKKSKTI--NNDLNPIWNEHYEFVV--EDSSTQHLTVKIYDDE 199 G SDP+ +++ + KK KT LNP +NE + F + E + V + D + Sbjct: 307 GLSDPYVKIHLMQNGKRLKKKKTTVKKKTLNPYFNESFSFEIPFEQIQKVQVVVTVLDYD 366 Query: 200 GLQPSEIIG 226 L +E IG Sbjct: 367 KLGKNEAIG 375 Score = 33.5 bits (75), Expect = 0.48 Identities = 17/39 (43%), Positives = 27/39 (69%), Gaps = 5/39 (12%) Frame = +2 Query: 494 LSVTVISAEDIPAMDVMGKADPFVVLYL-----KKGETK 595 L+V V+ A ++PA+D+ G +DP+V ++L KK ETK Sbjct: 159 LTVGVLQAAELPALDMGGTSDPYVKVFLLPDKKKKYETK 197
>SYT2_RAT (P29101) Synaptotagmin-2 (Synaptotagmin II) (SytII)| Length = 422 Score = 55.1 bits (131), Expect = 2e-07 Identities = 47/195 (24%), Positives = 84/195 (43%), Gaps = 5/195 (2%) Frame = +2 Query: 32 GKSDPFAVLYIRPLSAKTKKSKTINNDLNPIWNEHYEFVV--EDSSTQHLTVKIYDDEGL 205 G SDP+ +++ P K ++K LNP +NE + F V ++ + L + IYD + Sbjct: 176 GTSDPYVKVFLLPDKKKKYETKVHRKTLNPAFNETFTFKVPYQELGGKTLVMAIYDFDRF 235 Query: 206 QPSEIIGCARVDLSDIMPGKVKDVWLELVKDLEIQRDKKPR--GQVHLELLYYPFDKQEG 379 +IIG +V ++ + G+ + W +DL+ ++P G + L Y P Sbjct: 236 SKHDIIGEVKVPMNTVDLGQPIEEW----RDLQGGEKEEPEKLGDICTSLRYVP------ 285 Query: 380 VSNPFASQIQLTSLEKVLKTESNGYDVNQRKNVITRGVLSVTVISAEDIPAMDVMGKADP 559 T G L+V ++ A+++ MDV G +DP Sbjct: 286 ----------------------------------TAGKLTVCILEAKNLKKMDVGGLSDP 311 Query: 560 FVVLYL-KKGETKKK 601 +V ++L + G+ KK Sbjct: 312 YVKIHLMQNGKRLKK 326 Score = 34.3 bits (77), Expect = 0.28 Identities = 21/69 (30%), Positives = 33/69 (47%), Gaps = 4/69 (5%) Frame = +2 Query: 32 GKSDPFAVLYIRPLSAKTKKSKTI--NNDLNPIWNEHYEFVV--EDSSTQHLTVKIYDDE 199 G SDP+ +++ + KK KT LNP +NE + F + E + V + D + Sbjct: 307 GLSDPYVKIHLMQNGKRLKKKKTTVKKKTLNPYFNESFSFEIPFEQIQKVQVVVTVLDYD 366 Query: 200 GLQPSEIIG 226 L +E IG Sbjct: 367 KLGKNEAIG 375 Score = 33.5 bits (75), Expect = 0.48 Identities = 17/39 (43%), Positives = 27/39 (69%), Gaps = 5/39 (12%) Frame = +2 Query: 494 LSVTVISAEDIPAMDVMGKADPFVVLYL-----KKGETK 595 L+V V+ A ++PA+D+ G +DP+V ++L KK ETK Sbjct: 159 LTVGVLQAAELPALDMGGTSDPYVKVFLLPDKKKKYETK 197
>SY63_DISOM (P24507) Synaptotagmin C (Synaptic vesicle protein O-p65-C)| Length = 537 Score = 55.1 bits (131), Expect = 2e-07 Identities = 49/196 (25%), Positives = 81/196 (41%), Gaps = 6/196 (3%) Frame = +2 Query: 32 GKSDPFAVLYIRPLSAKTKKSKTINNDLNPIWNEHYEFVVEDSSTQH--LTVKIYDDEGL 205 G SDP+ +Y+ P K ++K LNPI+NE ++F V + Q+ L +YD + Sbjct: 270 GFSDPYVKIYLLPDRKKKFQTKVHRKTLNPIFNETFQFNVPFNELQNRKLHFSVYDFDRF 329 Query: 206 QPSEIIGCARVD----LSDIMPGKVKDVWLELVKDLEIQRDKKPRGQVHLELLYYPFDKQ 373 ++IG +D SD + +W ++ LE +K G+++ L Y P Sbjct: 330 SRHDLIGQVVLDNLLEFSDF--SEDTTIWRDI---LEATSEKADLGEINFSLCYLP---- 380 Query: 374 EGVSNPFASQIQLTSLEKVLKTESNGYDVNQRKNVITRGVLSVTVISAEDIPAMDVMGKA 553 T G L++T+I A ++ AMD+ G + Sbjct: 381 ------------------------------------TAGRLTITIIKATNLKAMDLTGFS 404 Query: 554 DPFVVLYLKKGETKKK 601 DP+V L E + K Sbjct: 405 DPYVKASLICDERRLK 420 Score = 42.0 bits (97), Expect = 0.001 Identities = 32/109 (29%), Positives = 53/109 (48%), Gaps = 4/109 (3%) Frame = +2 Query: 26 LVGKSDPF--AVLYIRPLSAKTKKSKTINNDLNPIWNEHYEFVVEDSSTQHLTV--KIYD 193 L G SDP+ A L K +K+ N LNP++NE F + + + +H+ V + D Sbjct: 400 LTGFSDPYVKASLICDERRLKKRKTSIKKNTLNPVYNEALVFDIPNENMEHVNVIIAVMD 459 Query: 194 DEGLQPSEIIGCARVDLSDIMPGKVKDVWLELVKDLEIQRDKKPRGQVH 340 + + +E+IG RV + PG ++ W E+ + +KP Q H Sbjct: 460 YDCIGHNEVIGMCRVGNATDGPG--REHWNEM-----LANPRKPIEQWH 501 Score = 32.7 bits (73), Expect = 0.82 Identities = 15/35 (42%), Positives = 21/35 (60%) Frame = +2 Query: 494 LSVTVISAEDIPAMDVMGKADPFVVLYLKKGETKK 598 L V ++ A D+PA D G +DP+V +YL KK Sbjct: 253 LVVKILKALDLPAKDANGFSDPYVKIYLLPDRKKK 287
>PA24A_BRARE (P50392) Cytosolic phospholipase A2 (cPLA2) (Phospholipase A2 group| IVA) [Includes: Phospholipase A2 (EC 3.1.1.4) (Phosphatidylcholine 2-acylhydrolase); Lysophospholipase (EC 3.1.1.5)] Length = 741 Score = 54.7 bits (130), Expect = 2e-07 Identities = 40/164 (24%), Positives = 77/164 (46%), Gaps = 1/164 (0%) Frame = +2 Query: 8 EGRTRXLVGKSDPFAVLYIRPLSAKTKKSKTINNDLNPIWNEHYEFVVEDSSTQHLTVKI 187 +G L+ DP+ L + K+++ INND+NP WNE +EF+++ + + L V + Sbjct: 26 KGAFGDLLDTPDPYVELSVPTTPESRKRTRHINNDINPKWNETFEFILDPNQSNVLEVTL 85 Query: 188 YDDEGLQPSEIIGCARVDLSDIMPGKVKDVWLELVKDLEIQRDKKPRGQVHLELLY-YPF 364 D + E +G A+ LS + +++ V L + K ++ D +L + Sbjct: 86 MDANYVM-DETLGTAKYSLSKLKVAQMEHVTLSIGKTTKVFLDLLLEVCASTDLRFSMTL 144 Query: 365 DKQEGVSNPFASQIQLTSLEKVLKTESNGYDVNQRKNVITRGVL 496 QE + + S++K+LK E+ + + + V T +L Sbjct: 145 CDQEKLFMQTRRDRVMLSIKKLLKMENPRFLPSSPREVPTIAIL 188
>SYT3_RAT (P40748) Synaptotagmin-3 (Synaptotagmin III) (SytIII)| Length = 588 Score = 54.7 bits (130), Expect = 2e-07 Identities = 49/197 (24%), Positives = 85/197 (43%), Gaps = 7/197 (3%) Frame = +2 Query: 32 GKSDPFAVLYIRPLSAKTKKSKTINNDLNPIWNEHYEFVV--EDSSTQHLTVKIYDDEGL 205 G SDP+ +Y+ P K ++K LNPI+NE ++F V + + + L +YD + Sbjct: 331 GFSDPYVKIYLLPDRKKKFQTKVHRKTLNPIFNETFQFSVPLAELAQRKLHFSVYDFDRF 390 Query: 206 QPSEIIGCARVD----LSDIMPGKVKDVWLELVKDLEIQRDKKPRGQVHLELLYYPFDKQ 373 ++IG +D L++ P + +W ++ LE +K G+++ L Y P Sbjct: 391 SRHDLIGQVVLDNLLELAEQPPD--RPLWRDI---LEGGSEKADLGELNFSLCYLP---- 441 Query: 374 EGVSNPFASQIQLTSLEKVLKTESNGYDVNQRKNVITRGVLSVTVISAEDIPAMDVMGKA 553 T G+L+VT+I A ++ AMD+ G + Sbjct: 442 ------------------------------------TAGLLTVTIIKASNLKAMDLTGFS 465 Query: 554 DPFV-VLYLKKGETKKK 601 DP+V + +G KK Sbjct: 466 DPYVKASLISEGRRLKK 482 Score = 37.4 bits (85), Expect = 0.033 Identities = 25/75 (33%), Positives = 38/75 (50%), Gaps = 4/75 (5%) Frame = +2 Query: 26 LVGKSDPFAVLYIRPLSAKTKKSKTI--NNDLNPIWNEHYEFVVEDSSTQH--LTVKIYD 193 L G SDP+ + + KK KT N LNP +NE F V S ++ L++ + D Sbjct: 461 LTGFSDPYVKASLISEGRRLKKRKTSIKKNTLNPTYNEALVFDVAPESVENVGLSIAVVD 520 Query: 194 DEGLQPSEIIGCARV 238 + + +E+IG RV Sbjct: 521 YDCIGHNEVIGVCRV 535 Score = 32.0 bits (71), Expect = 1.4 Identities = 15/35 (42%), Positives = 21/35 (60%) Frame = +2 Query: 494 LSVTVISAEDIPAMDVMGKADPFVVLYLKKGETKK 598 L V ++ A D+PA D G +DP+V +YL KK Sbjct: 314 LVVRILQALDLPAKDSNGFSDPYVKIYLLPDRKKK 348
>PA24A_CHICK (P49147) Cytosolic phospholipase A2 (cPLA2) (Phospholipase A2 group| IVA) [Includes: Phospholipase A2 (EC 3.1.1.4) (Phosphatidylcholine 2-acylhydrolase); Lysophospholipase (EC 3.1.1.5)] Length = 748 Score = 54.3 bits (129), Expect = 3e-07 Identities = 28/92 (30%), Positives = 49/92 (53%) Frame = +2 Query: 8 EGRTRXLVGKSDPFAVLYIRPLSAKTKKSKTINNDLNPIWNEHYEFVVEDSSTQHLTVKI 187 +G ++ DP+ L+I K++K NND+NP+WNE +EF+++ + L V + Sbjct: 32 KGAIGDMLDTPDPYVELFIPSAPDCRKRTKHFNNDVNPVWNETFEFILDPNQDNVLEVTL 91 Query: 188 YDDEGLQPSEIIGCARVDLSDIMPGKVKDVWL 283 D + E +G A +S + G+ K+V L Sbjct: 92 MDANYVM-DETLGMATFPISSLKLGEKKEVQL 122
>SYT3_MOUSE (O35681) Synaptotagmin-3 (Synaptotagmin III) (SytIII)| Length = 587 Score = 53.1 bits (126), Expect = 6e-07 Identities = 49/197 (24%), Positives = 84/197 (42%), Gaps = 7/197 (3%) Frame = +2 Query: 32 GKSDPFAVLYIRPLSAKTKKSKTINNDLNPIWNEHYEFVV--EDSSTQHLTVKIYDDEGL 205 G SDP+ +Y+ P K ++K LNPI+NE ++F V + + + L +YD + Sbjct: 330 GFSDPYVKIYLLPDRKKKFQTKVHRKTLNPIFNETFQFSVPLAELAQRKLHFSVYDFDRF 389 Query: 206 QPSEIIGCARVD----LSDIMPGKVKDVWLELVKDLEIQRDKKPRGQVHLELLYYPFDKQ 373 ++IG +D L++ P + +W ++ LE +K G+++ L Y P Sbjct: 390 SRHDLIGQVVLDNLLELAEQPPD--RPLWRDI---LEGGSEKADLGELNFSLCYLP---- 440 Query: 374 EGVSNPFASQIQLTSLEKVLKTESNGYDVNQRKNVITRGVLSVTVISAEDIPAMDVMGKA 553 T G L+VT+I A ++ AMD+ G + Sbjct: 441 ------------------------------------TAGRLTVTIIKASNLKAMDLTGFS 464 Query: 554 DPFV-VLYLKKGETKKK 601 DP+V + +G KK Sbjct: 465 DPYVKASLISEGRRLKK 481 Score = 37.4 bits (85), Expect = 0.033 Identities = 25/75 (33%), Positives = 38/75 (50%), Gaps = 4/75 (5%) Frame = +2 Query: 26 LVGKSDPFAVLYIRPLSAKTKKSKTI--NNDLNPIWNEHYEFVVEDSSTQH--LTVKIYD 193 L G SDP+ + + KK KT N LNP +NE F V S ++ L++ + D Sbjct: 460 LTGFSDPYVKASLISEGRRLKKRKTSIKKNTLNPTYNEALVFDVAPESVENVGLSIAVVD 519 Query: 194 DEGLQPSEIIGCARV 238 + + +E+IG RV Sbjct: 520 YDCIGHNEVIGVCRV 534 Score = 32.0 bits (71), Expect = 1.4 Identities = 15/35 (42%), Positives = 21/35 (60%) Frame = +2 Query: 494 LSVTVISAEDIPAMDVMGKADPFVVLYLKKGETKK 598 L V ++ A D+PA D G +DP+V +YL KK Sbjct: 313 LVVRILQALDLPAKDSNGFSDPYVKIYLLPDRKKK 347
>PA24A_RAT (P50393) Cytosolic phospholipase A2 (cPLA2) (Phospholipase A2 group| IVA) [Includes: Phospholipase A2 (EC 3.1.1.4) (Phosphatidylcholine 2-acylhydrolase); Lysophospholipase (EC 3.1.1.5)] Length = 752 Score = 53.1 bits (126), Expect = 6e-07 Identities = 25/90 (27%), Positives = 48/90 (53%) Frame = +2 Query: 8 EGRTRXLVGKSDPFAVLYIRPLSAKTKKSKTINNDLNPIWNEHYEFVVEDSSTQHLTVKI 187 +G ++ DP+ L+I K+++ NND+NP+WNE +EF+++ + L + + Sbjct: 32 KGTFGDMLDTPDPYVELFISTTPDSRKRTRHFNNDINPVWNETFEFILDPNQENVLEITL 91 Query: 188 YDDEGLQPSEIIGCARVDLSDIMPGKVKDV 277 D + E +G A +S + G+ K+V Sbjct: 92 MDANYVM-DETLGTATFPVSSMKVGEKKEV 120
>PA24A_HUMAN (P47712) Cytosolic phospholipase A2 (cPLA2) (Phospholipase A2 group| IVA) [Includes: Phospholipase A2 (EC 3.1.1.4) (Phosphatidylcholine 2-acylhydrolase); Lysophospholipase (EC 3.1.1.5)] Length = 749 Score = 53.1 bits (126), Expect = 6e-07 Identities = 25/90 (27%), Positives = 48/90 (53%) Frame = +2 Query: 8 EGRTRXLVGKSDPFAVLYIRPLSAKTKKSKTINNDLNPIWNEHYEFVVEDSSTQHLTVKI 187 +G ++ DP+ L+I K+++ NND+NP+WNE +EF+++ + L + + Sbjct: 32 KGAFGDMLDTPDPYVELFISTTPDSRKRTRHFNNDINPVWNETFEFILDPNQENVLEITL 91 Query: 188 YDDEGLQPSEIIGCARVDLSDIMPGKVKDV 277 D + E +G A +S + G+ K+V Sbjct: 92 MDANYVM-DETLGTATFTVSSMKVGEKKEV 120
>SY62_DISOM (P24506) Synaptotagmin B (Synaptic vesicle protein O-p65-B)| Length = 439 Score = 53.1 bits (126), Expect = 6e-07 Identities = 46/195 (23%), Positives = 82/195 (42%), Gaps = 5/195 (2%) Frame = +2 Query: 32 GKSDPFAVLYIRPLSAKTKKSKTINNDLNPIWNEHYEFVV--EDSSTQHLTVKIYDDEGL 205 G SDP+ +++ P K ++K LNP +NE + F V ++ + L + +YD + Sbjct: 193 GTSDPYVKVFLLPDKKKKYETKVQKKTLNPTFNESFVFKVPYQELGGKTLMMAVYDFDRF 252 Query: 206 QPSEIIGCARVDLSDIMPGKVKDVWLELVKDLEIQRDKKPR--GQVHLELLYYPFDKQEG 379 + IG V ++ + G+ + W +DLE ++P G + L Y P Sbjct: 253 SKHDCIGQVTVLMTKVDLGQQLEEW----RDLESAEKEEPEKLGDICTSLRYVP------ 302 Query: 380 VSNPFASQIQLTSLEKVLKTESNGYDVNQRKNVITRGVLSVTVISAEDIPAMDVMGKADP 559 T G L+V ++ A+++ MDV G +DP Sbjct: 303 ----------------------------------TAGKLTVCILEAKNLKKMDVGGLSDP 328 Query: 560 FVVLY-LKKGETKKK 601 +V ++ L+ G+ KK Sbjct: 329 YVKIHLLQNGKRLKK 343 Score = 34.3 bits (77), Expect = 0.28 Identities = 20/69 (28%), Positives = 34/69 (49%), Gaps = 4/69 (5%) Frame = +2 Query: 32 GKSDPFAVLYIRPLSAKTKKSKTI--NNDLNPIWNEHYEFVV--EDSSTQHLTVKIYDDE 199 G SDP+ +++ + KK KT N LNP +NE + F + E + V + D + Sbjct: 324 GLSDPYVKIHLLQNGKRLKKKKTTVKKNTLNPYYNESFSFEIPFEQIQKVQVCVTVLDYD 383 Query: 200 GLQPSEIIG 226 + ++ IG Sbjct: 384 KIGKNDAIG 392 Score = 33.9 bits (76), Expect = 0.37 Identities = 17/39 (43%), Positives = 27/39 (69%), Gaps = 5/39 (12%) Frame = +2 Query: 494 LSVTVISAEDIPAMDVMGKADPFVVLYL-----KKGETK 595 L+V +I A ++PA+D+ G +DP+V ++L KK ETK Sbjct: 176 LTVGIIQAAELPALDMGGTSDPYVKVFLLPDKKKKYETK 214
>PA24A_MOUSE (P47713) Cytosolic phospholipase A2 (cPLA2) (Phospholipase A2 group| IVA) [Includes: Phospholipase A2 (EC 3.1.1.4) (Phosphatidylcholine 2-acylhydrolase); Lysophospholipase (EC 3.1.1.5)] Length = 748 Score = 53.1 bits (126), Expect = 6e-07 Identities = 25/90 (27%), Positives = 48/90 (53%) Frame = +2 Query: 8 EGRTRXLVGKSDPFAVLYIRPLSAKTKKSKTINNDLNPIWNEHYEFVVEDSSTQHLTVKI 187 +G ++ DP+ L+I K+++ NND+NP+WNE +EF+++ + L + + Sbjct: 32 KGTFGDMLDTPDPYVELFISTTPDSRKRTRHFNNDINPVWNETFEFILDPNQENVLEITL 91 Query: 188 YDDEGLQPSEIIGCARVDLSDIMPGKVKDV 277 D + E +G A +S + G+ K+V Sbjct: 92 MDANYVM-DETLGTATFPVSSMKVGEKKEV 120
>SYT3_HUMAN (Q9BQG1) Synaptotagmin-3 (Synaptotagmin III) (SytIII)| Length = 590 Score = 52.8 bits (125), Expect = 8e-07 Identities = 48/197 (24%), Positives = 84/197 (42%), Gaps = 7/197 (3%) Frame = +2 Query: 32 GKSDPFAVLYIRPLSAKTKKSKTINNDLNPIWNEHYEFVV--EDSSTQHLTVKIYDDEGL 205 G SDP+ +Y+ P K ++K LNP++NE ++F V + + + L +YD + Sbjct: 333 GFSDPYVKIYLLPDRKKKFQTKVHRKTLNPVFNETFQFSVPLAELAQRKLHFSVYDFDRF 392 Query: 206 QPSEIIGCARVD----LSDIMPGKVKDVWLELVKDLEIQRDKKPRGQVHLELLYYPFDKQ 373 ++IG +D L++ P + +W ++V E +K G+++ L Y P Sbjct: 393 SRHDLIGQVVLDNLLELAEQPPD--RPLWRDIV---EGGSEKADLGELNFSLCYLP---- 443 Query: 374 EGVSNPFASQIQLTSLEKVLKTESNGYDVNQRKNVITRGVLSVTVISAEDIPAMDVMGKA 553 T G L+VT+I A ++ AMD+ G + Sbjct: 444 ------------------------------------TAGRLTVTIIKASNLKAMDLTGFS 467 Query: 554 DPFV-VLYLKKGETKKK 601 DP+V + +G KK Sbjct: 468 DPYVKASLISEGRRLKK 484 Score = 38.1 bits (87), Expect = 0.020 Identities = 28/93 (30%), Positives = 45/93 (48%), Gaps = 4/93 (4%) Frame = +2 Query: 26 LVGKSDPFAVLYIRPLSAKTKKSKTI--NNDLNPIWNEHYEFVVEDSSTQH--LTVKIYD 193 L G SDP+ + + KK KT N LNP +NE F V S ++ L++ + D Sbjct: 463 LTGFSDPYVKASLISEGRRLKKRKTSIKKNTLNPTYNEALVFDVAPESVENVGLSIAVVD 522 Query: 194 DEGLQPSEIIGCARVDLSDIMPGKVKDVWLELV 292 + + +E+IG RV D ++ W E++ Sbjct: 523 YDCIGHNEVIGVCRVG-PDAADPHGREHWAEML 554 Score = 32.0 bits (71), Expect = 1.4 Identities = 15/35 (42%), Positives = 21/35 (60%) Frame = +2 Query: 494 LSVTVISAEDIPAMDVMGKADPFVVLYLKKGETKK 598 L V ++ A D+PA D G +DP+V +YL KK Sbjct: 316 LVVRILQALDLPAKDSNGFSDPYVKIYLLPDRKKK 350
>SYT2_HUMAN (Q8N9I0) Synaptotagmin-2 (Synaptotagmin II) (SytII)| Length = 419 Score = 52.4 bits (124), Expect = 1e-06 Identities = 46/195 (23%), Positives = 83/195 (42%), Gaps = 5/195 (2%) Frame = +2 Query: 32 GKSDPFAVLYIRPLSAKTKKSKTINNDLNPIWNEHYEFVV--EDSSTQHLTVKIYDDEGL 205 G SDP+ +++ P K ++K LNP +NE + F V ++ + L + IYD + Sbjct: 173 GTSDPYVKVFLLPDKKKKYETKVHRKTLNPAFNETFTFKVPYQELGGKTLVMAIYDFDRF 232 Query: 206 QPSEIIGCARVDLSDIMPGKVKDVWLELVKDLEIQRDKKPR--GQVHLELLYYPFDKQEG 379 +IIG +V ++ + G+ + W +DL+ ++P G + L Y P Sbjct: 233 SKHDIIGEVKVPMNTVDLGQPIEEW----RDLQGGEKEEPEKLGDICTSLRYVP------ 282 Query: 380 VSNPFASQIQLTSLEKVLKTESNGYDVNQRKNVITRGVLSVTVISAEDIPAMDVMGKADP 559 T G L+V ++ A+++ MDV G +DP Sbjct: 283 ----------------------------------TAGKLTVCILEAKNLKKMDVGGLSDP 308 Query: 560 FVVLYL-KKGETKKK 601 + ++L + G+ KK Sbjct: 309 YGKIHLMQNGKRLKK 323 Score = 34.3 bits (77), Expect = 0.28 Identities = 21/69 (30%), Positives = 33/69 (47%), Gaps = 4/69 (5%) Frame = +2 Query: 32 GKSDPFAVLYIRPLSAKTKKSKTI--NNDLNPIWNEHYEFVV--EDSSTQHLTVKIYDDE 199 G SDP+ +++ + KK KT LNP +NE + F + E + V + D + Sbjct: 304 GLSDPYGKIHLMQNGKRLKKKKTTVKKKTLNPYFNESFSFEIPFEQIQKVQVVVTVLDYD 363 Query: 200 GLQPSEIIG 226 L +E IG Sbjct: 364 KLGKNEAIG 372 Score = 33.5 bits (75), Expect = 0.48 Identities = 17/39 (43%), Positives = 27/39 (69%), Gaps = 5/39 (12%) Frame = +2 Query: 494 LSVTVISAEDIPAMDVMGKADPFVVLYL-----KKGETK 595 L+V V+ A ++PA+D+ G +DP+V ++L KK ETK Sbjct: 156 LTVGVLQAAELPALDMGGTSDPYVKVFLLPDKKKKYETK 194
>PA24A_HORSE (O77793) Cytosolic phospholipase A2 (cPLA2) (Phospholipase A2 group| IVA) [Includes: Phospholipase A2 (EC 3.1.1.4) (Phosphatidylcholine 2-acylhydrolase); Lysophospholipase (EC 3.1.1.5)] Length = 749 Score = 52.4 bits (124), Expect = 1e-06 Identities = 25/90 (27%), Positives = 48/90 (53%) Frame = +2 Query: 8 EGRTRXLVGKSDPFAVLYIRPLSAKTKKSKTINNDLNPIWNEHYEFVVEDSSTQHLTVKI 187 +G ++ DP+ L+I K+++ NN++NP+WNE +EF+++ + L + + Sbjct: 32 KGAFGDMLDTPDPYVELFISSTPDSRKRTRHFNNNINPVWNETFEFILDPNQENVLEITL 91 Query: 188 YDDEGLQPSEIIGCARVDLSDIMPGKVKDV 277 D + E +G A LS + G+ K+V Sbjct: 92 MDANYVM-DETLGTATFTLSSMKVGEKKEV 120
>SY65_DROME (P21521) Synaptotagmin (p65)| Length = 474 Score = 52.0 bits (123), Expect = 1e-06 Identities = 45/194 (23%), Positives = 80/194 (41%), Gaps = 4/194 (2%) Frame = +2 Query: 32 GKSDPFAVLYIRPLSAKTKKSKTINNDLNPIWNEHYEF---VVEDSSTQHLTVKIYDDEG 202 G SDP+ +Y+ P K ++K L+P++NE + F D+ + L I+D + Sbjct: 226 GTSDPYVKVYLLPDKKKKFETKVHRKTLSPVFNETFTFKSLPYADAMNKTLVFAIFDFDR 285 Query: 203 LQPSEIIGCARVDLSDIMPGKVKDVWLELVKDLEIQRDKKPRGQVHLELLYYPFDKQEGV 382 + IG +V L I + + W +LV +E + ++ G + L Y P Sbjct: 286 FSKHDQIGEVKVPLCTIDLAQTIEEWRDLV-SVEGEGGQEKLGDICFSLRYVP------- 337 Query: 383 SNPFASQIQLTSLEKVLKTESNGYDVNQRKNVITRGVLSVTVISAEDIPAMDVMGKADPF 562 T G L+V ++ A+++ MDV G +DP+ Sbjct: 338 ---------------------------------TAGKLTVVILEAKNLKKMDVGGLSDPY 364 Query: 563 V-VLYLKKGETKKK 601 V + ++ G+ KK Sbjct: 365 VKIAIMQNGKRLKK 378 Score = 40.8 bits (94), Expect = 0.003 Identities = 21/39 (53%), Positives = 29/39 (74%), Gaps = 5/39 (12%) Frame = +2 Query: 494 LSVTVISAEDIPAMDVMGKADPFVVLYL-----KKGETK 595 L+VTVI AE++PA+D+ G +DP+V +YL KK ETK Sbjct: 209 LAVTVIQAEELPALDMGGTSDPYVKVYLLPDKKKKFETK 247 Score = 33.1 bits (74), Expect = 0.63 Identities = 24/69 (34%), Positives = 32/69 (46%), Gaps = 4/69 (5%) Frame = +2 Query: 32 GKSDPFAVLYIRPLSAKTKKSKTINND--LNPIWNEHYEFVVEDSSTQH--LTVKIYDDE 199 G SDP+ + I + KK KT LNP +NE + F V Q L V + D + Sbjct: 359 GLSDPYVKIAIMQNGKRLKKKKTSVKKCTLNPYYNESFSFEVPFEQMQKICLVVTVVDYD 418 Query: 200 GLQPSEIIG 226 + SE IG Sbjct: 419 RIGTSEPIG 427
>KPC1_LYTPI (Q25378) Protein kinase C (EC 2.7.11.13)| Length = 658 Score = 52.0 bits (123), Expect = 1e-06 Identities = 52/190 (27%), Positives = 85/190 (44%), Gaps = 5/190 (2%) Frame = +2 Query: 32 GKSDPFAVLYIRPLSAKT--KKSKTINNDLNPIWNEHYEFVVEDSS-TQHLTVKIYDDEG 202 G SDPF L + P + KK++TI LNP W E ++F +ED+ + L V+++D + Sbjct: 181 GLSDPFVKLKLIPDQKRETKKKTRTIKGSLNPTWGESFDFNLEDTDRNRRLLVEVWDWDR 240 Query: 203 LQPSEIIGCARVDLSDIMPGKVKDVWLELVKDLEIQRDKKPRGQVHLELLYYP-FDKQEG 379 ++ +G +S++M V D W +L+ GQ E P + E Sbjct: 241 ATRNDFMGALSFGISELMKAGV-DAWYKLL------------GQEEGEYYNVPAIAETES 287 Query: 380 VSNPFASQIQLTSLEKVLKTESNGYDVNQRKNVITRGVLSVTVISAEDIPAMDVMGKAD- 556 + +LTS K L + + Q N ++ + V+ A D + V+GK Sbjct: 288 ID-------ELTSNIKKLPMPTQEHVKPQNSNSMS----GMGVVRASDFNFLSVLGKGSF 336 Query: 557 PFVVLYLKKG 586 V+L KKG Sbjct: 337 GKVMLAEKKG 346 Score = 33.1 bits (74), Expect = 0.63 Identities = 20/39 (51%), Positives = 25/39 (64%), Gaps = 3/39 (7%) Frame = +2 Query: 494 LSVTVISAEDIPAMDVMGKADPFVVLYL---KKGETKKK 601 L VTV A+++ MD G +DPFV L L +K ETKKK Sbjct: 164 LQVTVAEAKNLIPMDPNGLSDPFVKLKLIPDQKRETKKK 202
>YC31_SCHPO (O14065) Hypothetical protein C962.01 in chromosome III| Length = 1429 Score = 50.8 bits (120), Expect = 3e-06 Identities = 27/77 (35%), Positives = 43/77 (55%) Frame = +2 Query: 29 VGKSDPFAVLYIRPLSAKTKKSKTINNDLNPIWNEHYEFVVEDSSTQHLTVKIYDDEGLQ 208 + SDPF VL + SA KSK I +LNP+WNE + VV++ L + YD + + Sbjct: 1095 IRSSDPFVVLKLNGESAF--KSKVIKKNLNPVWNEEADIVVQNRVLDVLELVCYDWDMGE 1152 Query: 209 PSEIIGCARVDLSDIMP 259 +++G + +DL + P Sbjct: 1153 KPDVLGTSNIDLLSLEP 1169 Score = 32.7 bits (73), Expect = 0.82 Identities = 21/59 (35%), Positives = 33/59 (55%), Gaps = 3/59 (5%) Frame = +2 Query: 35 KSDPFAVLYIRPLSAKTKKSKTIN--NDLNPIWNE-HYEFVVEDSSTQHLTVKIYDDEG 202 KSDP+A R + + ++T+ N+LNPIWNE Y ++ D+ T L Y++ G Sbjct: 778 KSDPYA----RVIVGNSVVARTVYTPNNLNPIWNEILYVPIMADTKTIDLEAMDYEESG 832
>SYT7_HUMAN (O43581) Synaptotagmin-7 (Synaptotagmin VII) (SytVII)| Length = 402 Score = 50.8 bits (120), Expect = 3e-06 Identities = 51/197 (25%), Positives = 82/197 (41%), Gaps = 8/197 (4%) Frame = +2 Query: 32 GKSDPFAVLYIRPLSAKTKKSKTINNDLNPIWNEHY---EFVVEDSSTQHLTVKIYDDEG 202 G SDPF +Y+ P K+K +LNP WNE + F E + L +++ D + Sbjct: 168 GTSDPFVKIYLLPDKKHKLKTKVKRKNLNPHWNETFLFEGFPYEKVVQRILYLQVLDYDR 227 Query: 203 LQPSEIIGCARVDLSDIMPGKVKDVWLELVKDLEIQRD-KKPRGQVHLELLYYPFDKQEG 379 ++ IG + L+ + +++ W KDL+ D RG++ L L Y Sbjct: 228 FSRNDPIGEVSIPLNKVDLTQMQTFW----KDLKPCSDGSGSRGELLLSLCY-------- 275 Query: 380 VSNPFASQIQLTSLEKVLKTESNGYDVNQRKNVITRGVLSVTVISAEDIPAMDVMGKADP 559 NP A+ I V +I A ++ AMD+ G +DP Sbjct: 276 --NPSANSI------------------------------IVNIIKARNLKAMDIGGTSDP 303 Query: 560 FVVLYL----KKGETKK 598 +V ++L K+ E KK Sbjct: 304 YVKVWLMYKDKRVEKKK 320 Score = 36.6 bits (83), Expect = 0.057 Identities = 29/108 (26%), Positives = 54/108 (50%), Gaps = 5/108 (4%) Frame = +2 Query: 32 GKSDPFAVLYIRPLSAKTKKSKTIN--NDLNPIWNEHYEFVVEDSSTQHLT--VKIYDDE 199 G SDP+ +++ + +K KT+ +LNP +NE + F + + T + + D + Sbjct: 299 GTSDPYVKVWLMYKDKRVEKKKTVTMKRNLNPNFNESFAFDIPTEKLRETTIIITVMDKD 358 Query: 200 GLQPSEIIGCARVDLS-DIMPGKVKDVWLELVKDLEIQRDKKPRGQVH 340 L +++IG ++ LS PG+V W ++ I R ++P Q H Sbjct: 359 KLSRNDVIG--KIYLSWKSGPGEVXH-WKDM-----IARPRQPVAQWH 398 Score = 33.9 bits (76), Expect = 0.37 Identities = 16/39 (41%), Positives = 26/39 (66%), Gaps = 3/39 (7%) Frame = +2 Query: 494 LSVTVISAEDIPAMDVMGKADPFVVLYL---KKGETKKK 601 L++ ++ A+++PA D G +DPFV +YL KK + K K Sbjct: 151 LTLKIMKAQELPAKDFSGTSDPFVKIYLLPDKKHKLKTK 189
>SYT9_RAT (Q925C0) Synaptotagmin-9 (Synaptotagmin IX) (SytIX) (Synaptotagmin| V) (Synaptotagmin 5) Length = 491 Score = 49.7 bits (117), Expect = 6e-06 Identities = 46/189 (24%), Positives = 75/189 (39%), Gaps = 7/189 (3%) Frame = +2 Query: 32 GKSDPFAVLYIRPLSAKTKKSKTINNDLNPIWNEHYEFVV--EDSSTQHLTVKIYDDEGL 205 G SDP+ +Y+ P ++K LNP+++E + F V D + L +YD + Sbjct: 254 GTSDPYVKIYLLPDRKTKHQTKVHRKTLNPVFDEVFLFPVHYNDLEARKLHFSVYDFDRF 313 Query: 206 QPSEIIGCARV----DLSDIMPGKVKDVWLELVKDLE-IQRDKKPRGQVHLELLYYPFDK 370 ++IG V DL+D + L KD+E + D G++ L Y P Sbjct: 314 SRHDLIGQVVVDHFFDLADFPRECI------LWKDIEYVTNDNVDLGELMFSLCYLP--- 364 Query: 371 QEGVSNPFASQIQLTSLEKVLKTESNGYDVNQRKNVITRGVLSVTVISAEDIPAMDVMGK 550 T G L++T+I A ++ AMD+ G Sbjct: 365 -------------------------------------TAGRLTITIIKARNLKAMDITGA 387 Query: 551 ADPFVVLYL 577 +DP+V + L Sbjct: 388 SDPYVKVSL 396 Score = 40.0 bits (92), Expect = 0.005 Identities = 28/93 (30%), Positives = 46/93 (49%), Gaps = 4/93 (4%) Frame = +2 Query: 26 LVGKSDPFAVLYIRPLSAKTKKSKTIN--NDLNPIWNEHYEFVVEDSSTQ--HLTVKIYD 193 + G SDP+ + + + KK KT N LNP++NE F V S HL++ + D Sbjct: 384 ITGASDPYVKVSLMCDGRRLKKRKTSTKRNTLNPVYNEAIVFDVPPESIDQIHLSIAVMD 443 Query: 194 DEGLQPSEIIGCARVDLSDIMPGKVKDVWLELV 292 + + +E+IG +V G +D W E++ Sbjct: 444 YDRVGHNEVIGVCQVGNEAERLG--RDHWSEML 474
>SYT9_MOUSE (Q9R0N9) Synaptotagmin-9 (Synaptotagmin IX) (SytIX) (Synaptotagmin| V) Length = 491 Score = 49.7 bits (117), Expect = 6e-06 Identities = 46/189 (24%), Positives = 75/189 (39%), Gaps = 7/189 (3%) Frame = +2 Query: 32 GKSDPFAVLYIRPLSAKTKKSKTINNDLNPIWNEHYEFVV--EDSSTQHLTVKIYDDEGL 205 G SDP+ +Y+ P ++K LNP+++E + F V D + L +YD + Sbjct: 254 GTSDPYVKIYLLPDRKTKHQTKVHRKTLNPVFDEVFLFPVHYNDLEARKLHFSVYDFDRF 313 Query: 206 QPSEIIGCARV----DLSDIMPGKVKDVWLELVKDLE-IQRDKKPRGQVHLELLYYPFDK 370 ++IG V DL+D + L KD+E + D G++ L Y P Sbjct: 314 SRHDLIGQVVVDHFFDLADFPRECI------LWKDIEYVTNDNVDLGELMFSLCYLP--- 364 Query: 371 QEGVSNPFASQIQLTSLEKVLKTESNGYDVNQRKNVITRGVLSVTVISAEDIPAMDVMGK 550 T G L++T+I A ++ AMD+ G Sbjct: 365 -------------------------------------TAGRLTITIIKARNLKAMDITGA 387 Query: 551 ADPFVVLYL 577 +DP+V + L Sbjct: 388 SDPYVKVSL 396 Score = 40.0 bits (92), Expect = 0.005 Identities = 28/93 (30%), Positives = 46/93 (49%), Gaps = 4/93 (4%) Frame = +2 Query: 26 LVGKSDPFAVLYIRPLSAKTKKSKTIN--NDLNPIWNEHYEFVVEDSSTQ--HLTVKIYD 193 + G SDP+ + + + KK KT N LNP++NE F V S HL++ + D Sbjct: 384 ITGASDPYVKVSLMCDGRRLKKRKTSTKRNTLNPVYNEAIVFDVPPESIDQIHLSIAVMD 443 Query: 194 DEGLQPSEIIGCARVDLSDIMPGKVKDVWLELV 292 + + +E+IG +V G +D W E++ Sbjct: 444 YDRVGHNEVIGVCQVGNEAERLG--RDHWSEML 474
>SYT9_HUMAN (Q86SS6) Synaptotagmin-9 (Synaptotagmin IX) (SytIX)| Length = 491 Score = 49.7 bits (117), Expect = 6e-06 Identities = 46/189 (24%), Positives = 75/189 (39%), Gaps = 7/189 (3%) Frame = +2 Query: 32 GKSDPFAVLYIRPLSAKTKKSKTINNDLNPIWNEHYEFVV--EDSSTQHLTVKIYDDEGL 205 G SDP+ +Y+ P ++K LNP+++E + F V D + L +YD + Sbjct: 254 GTSDPYVKIYLLPDRKTKHQTKVHRKTLNPVFDEVFLFPVPYNDLEARKLHFSVYDFDRF 313 Query: 206 QPSEIIGCARV----DLSDIMPGKVKDVWLELVKDLE-IQRDKKPRGQVHLELLYYPFDK 370 ++IG V DL+D + L KD+E + D G++ L Y P Sbjct: 314 SRHDLIGQVVVDHFLDLADFPRECI------LWKDIEYVTNDNVDLGELMFSLCYLP--- 364 Query: 371 QEGVSNPFASQIQLTSLEKVLKTESNGYDVNQRKNVITRGVLSVTVISAEDIPAMDVMGK 550 T G L++T+I A ++ AMD+ G Sbjct: 365 -------------------------------------TAGRLTITIIKARNLKAMDITGA 387 Query: 551 ADPFVVLYL 577 +DP+V + L Sbjct: 388 SDPYVKVSL 396 Score = 40.0 bits (92), Expect = 0.005 Identities = 29/93 (31%), Positives = 47/93 (50%), Gaps = 4/93 (4%) Frame = +2 Query: 26 LVGKSDPFAVLYIRPLSAKTKKSKTIN--NDLNPIWNEHYEFVV--EDSSTQHLTVKIYD 193 + G SDP+ + + + KK KT N LNP++NE F V E+ HL++ + D Sbjct: 384 ITGASDPYVKVSLMCDGRRLKKRKTSTKRNTLNPVYNEAIVFDVPPENIDQIHLSIAVMD 443 Query: 194 DEGLQPSEIIGCARVDLSDIMPGKVKDVWLELV 292 + + +EIIG +V G +D W E++ Sbjct: 444 YDRVGHNEIIGVCQVGNEAERLG--RDHWSEML 474
>SYT7_MOUSE (Q9R0N7) Synaptotagmin-7 (Synaptotagmin VII) (SytVII)| Length = 403 Score = 49.3 bits (116), Expect = 8e-06 Identities = 50/197 (25%), Positives = 82/197 (41%), Gaps = 8/197 (4%) Frame = +2 Query: 32 GKSDPFAVLYIRPLSAKTKKSKTINNDLNPIWNEHY---EFVVEDSSTQHLTVKIYDDEG 202 G SDPF +Y+ P ++K +LNP WNE + F E + L +++ D + Sbjct: 169 GTSDPFVKIYLLPDKKHKLETKVKRKNLNPHWNETFLFEGFPYEKVVQRVLYLQVLDYDR 228 Query: 203 LQPSEIIGCARVDLSDIMPGKVKDVWLELVKDLEIQRD-KKPRGQVHLELLYYPFDKQEG 379 ++ IG + L+ + +++ W KDL+ D RG++ L L Y Sbjct: 229 FSRNDPIGEVSIPLNKVDLTQMQTFW----KDLKPCSDGSGSRGELLLSLCY-------- 276 Query: 380 VSNPFASQIQLTSLEKVLKTESNGYDVNQRKNVITRGVLSVTVISAEDIPAMDVMGKADP 559 NP A+ I V +I A ++ AMD+ G +DP Sbjct: 277 --NPSANSI------------------------------IVNIIKARNLKAMDIGGTSDP 304 Query: 560 FVVLYL----KKGETKK 598 +V ++L K+ E KK Sbjct: 305 YVKVWLMYKDKRVEKKK 321 Score = 41.6 bits (96), Expect = 0.002 Identities = 31/108 (28%), Positives = 56/108 (51%), Gaps = 5/108 (4%) Frame = +2 Query: 32 GKSDPFAVLYIRPLSAKTKKSKTINN--DLNPIWNEHYEFVVEDSSTQHLT--VKIYDDE 199 G SDP+ +++ + +K KT+ +LNPI+NE + F + + T + + D + Sbjct: 300 GTSDPYVKVWLMYKDKRVEKKKTVTKKRNLNPIFNESFAFDIPTEKLRETTIIITVMDKD 359 Query: 200 GLQPSEIIGCARVDLS-DIMPGKVKDVWLELVKDLEIQRDKKPRGQVH 340 L +++IG ++ LS PG+VK W ++ I R ++P Q H Sbjct: 360 KLSRNDVIG--KIYLSWKSGPGEVKH-WKDM-----IARPRQPVAQWH 399 Score = 35.0 bits (79), Expect = 0.17 Identities = 19/41 (46%), Positives = 26/41 (63%), Gaps = 5/41 (12%) Frame = +2 Query: 494 LSVTVISAEDIPAMDVMGKADPFVVLYL-----KKGETKKK 601 L+V V+ A+++PA D G +DPFV +YL K ETK K Sbjct: 152 LTVKVMKAQELPAKDFSGTSDPFVKIYLLPDKKHKLETKVK 192
>KPCB_BOVIN (P05126) Protein kinase C beta type (EC 2.7.11.13) (PKC-beta)| (PKC-B) Length = 672 Score = 48.5 bits (114), Expect = 1e-05 Identities = 40/146 (27%), Positives = 70/146 (47%), Gaps = 6/146 (4%) Frame = +2 Query: 32 GKSDPFAVLYI--RPLSAKTKKSKTINNDLNPIWNEHYEFVVEDS-STQHLTVKIYDDEG 202 G SDP+ L + P S +K+KTI LNP WNE + F +++S + L+V+I+D + Sbjct: 189 GLSDPYVKLKLIPDPKSESKQKTKTIKCSLNPEWNETFRFQLKESDKDRRLSVEIWDWDL 248 Query: 203 LQPSEIIGCARVDLSDIMPGKVKDVWLELVKDLE---IQRDKKPRGQVHLELLYYPFDKQ 373 ++ +G +S++ V D W +L+ E P G E L F++ Sbjct: 249 TSRNDFMGSLSFGISELQKAGV-DGWFKLLSQEEGEYFNVPVPPEGSEGNEELRQKFERA 307 Query: 374 EGVSNPFASQIQLTSLEKVLKTESNG 451 + P + + T+ + K ++NG Sbjct: 308 KIGPGPKTPEEKTTN--TISKFDNNG 331
>KPCB_HUMAN (P05771) Protein kinase C beta type (EC 2.7.11.13) (PKC-beta)| (PKC-B) Length = 670 Score = 48.5 bits (114), Expect = 1e-05 Identities = 30/94 (31%), Positives = 51/94 (54%), Gaps = 3/94 (3%) Frame = +2 Query: 32 GKSDPFAVLYI--RPLSAKTKKSKTINNDLNPIWNEHYEFVVEDS-STQHLTVKIYDDEG 202 G SDP+ L + P S +K+KTI LNP WNE + F +++S + L+V+I+D + Sbjct: 189 GLSDPYVKLKLIPDPKSESKQKTKTIKCSLNPEWNETFRFQLKESDKDRRLSVEIWDWDL 248 Query: 203 LQPSEIIGCARVDLSDIMPGKVKDVWLELVKDLE 304 ++ +G +S++ V D W +L+ E Sbjct: 249 TSRNDFMGSLSFGISELQKASV-DGWFKLLSQEE 281
>KPCB_MOUSE (P68404) Protein kinase C beta type (EC 2.7.11.13) (PKC-beta)| (PKC-B) Length = 672 Score = 47.8 bits (112), Expect = 2e-05 Identities = 30/94 (31%), Positives = 51/94 (54%), Gaps = 3/94 (3%) Frame = +2 Query: 32 GKSDPFAVLYI--RPLSAKTKKSKTINNDLNPIWNEHYEFVVEDS-STQHLTVKIYDDEG 202 G SDP+ L + P S +K+KTI LNP WNE + F +++S + L+V+I+D + Sbjct: 189 GLSDPYVKLKLIPDPKSESKQKTKTIKCSLNPEWNETFRFQLKESDKDRRLSVEIWDWDL 248 Query: 203 LQPSEIIGCARVDLSDIMPGKVKDVWLELVKDLE 304 ++ +G +S++ V D W +L+ E Sbjct: 249 TSRNDFMGSLSFGISELQKAGV-DGWFKLLSQEE 281
>SYT10_RAT (O08625) Synaptotagmin-10 (Synaptotagmin X) (SytX)| Length = 523 Score = 47.8 bits (112), Expect = 2e-05 Identities = 47/202 (23%), Positives = 82/202 (40%), Gaps = 8/202 (3%) Frame = +2 Query: 20 RXLVGKSDPFAVLYIRPLSAKTKKSKTINNDLNPIWNEHYEF--VVEDSSTQHLTVKIYD 193 + G SDP+ +Y+ P K +++ LNP+++E ++F V + S + L IYD Sbjct: 261 KDFTGTSDPYVKIYLLPDRKKKFQTRVHRKTLNPLFDELFQFPVVYDQLSNRKLHFSIYD 320 Query: 194 DEGLQPSEIIGCARVD----LSDIMPGKVKDVWLELVKDLEIQRDKK-PRGQVHLELLYY 358 + ++IG +D +SD+ + VW KD+ + G++ L Y Sbjct: 321 FDRFSRHDMIGEVILDNLFEVSDL--SREATVW----KDIHCATTESIDLGEIMFSLCYL 374 Query: 359 PFDKQEGVSNPFASQIQLTSLEKVLKTESNGYDVNQRKNVITRGVLSVTVISAEDIPAMD 538 P T G +++TVI ++ AMD Sbjct: 375 P----------------------------------------TAGRMTLTVIKCRNLKAMD 394 Query: 539 VMGKADPFV-VLYLKKGETKKK 601 + G +DP+V V + +G KK Sbjct: 395 ITGSSDPYVKVSLMCEGRRLKK 416 Score = 40.8 bits (94), Expect = 0.003 Identities = 38/131 (29%), Positives = 58/131 (44%), Gaps = 9/131 (6%) Frame = +2 Query: 26 LVGKSDPFAVLYIRPLSAKTKKSKTIN--NDLNPIWNEHYEFVV--EDSSTQHLTVKIYD 193 + G SDP+ + + + KK KT N LNP++NE F + E+ L + + D Sbjct: 395 ITGSSDPYVKVSLMCEGRRLKKRKTTTKKNTLNPVYNEAIIFDIPPENVDQVSLCIAVMD 454 Query: 194 DEGLQPSEIIGCARVDLSDIMPGKVKDVWLELVKDLEIQRDKKPRGQVHLELLYYP---- 361 + + +E+IG R L G +D W E+ + +KP H LL P Sbjct: 455 YDRVGHNEVIGVCRTGLD--AEGLGRDHWNEM-----LAYHRKPITHWH-PLLELPGRAT 506 Query: 362 -FDKQEGVSNP 391 FD Q S+P Sbjct: 507 SFDSQGSCSSP 517 Score = 34.7 bits (78), Expect = 0.22 Identities = 16/36 (44%), Positives = 22/36 (61%) Frame = +2 Query: 491 VLSVTVISAEDIPAMDVMGKADPFVVLYLKKGETKK 598 +L V +I A D+PA D G +DP+V +YL KK Sbjct: 247 LLVVKIIKALDLPAKDFTGTSDPYVKIYLLPDRKKK 282
>SYT10_MOUSE (Q9R0N4) Synaptotagmin-10 (Synaptotagmin X) (SytX)| Length = 523 Score = 47.8 bits (112), Expect = 2e-05 Identities = 47/202 (23%), Positives = 82/202 (40%), Gaps = 8/202 (3%) Frame = +2 Query: 20 RXLVGKSDPFAVLYIRPLSAKTKKSKTINNDLNPIWNEHYEF--VVEDSSTQHLTVKIYD 193 + G SDP+ +Y+ P K +++ LNP+++E ++F V + S + L IYD Sbjct: 261 KDFTGTSDPYVKIYLLPDRKKKFQTRVHRKTLNPLFDELFQFPVVYDQLSNRKLHFSIYD 320 Query: 194 DEGLQPSEIIGCARVD----LSDIMPGKVKDVWLELVKDLEIQRDKK-PRGQVHLELLYY 358 + ++IG +D +SD+ + VW KD+ + G++ L Y Sbjct: 321 FDRFSRHDMIGEVILDNLFEVSDL--SREATVW----KDIHCATTESIDLGEIMFSLCYL 374 Query: 359 PFDKQEGVSNPFASQIQLTSLEKVLKTESNGYDVNQRKNVITRGVLSVTVISAEDIPAMD 538 P T G +++TVI ++ AMD Sbjct: 375 P----------------------------------------TAGRMTLTVIKCRNLKAMD 394 Query: 539 VMGKADPFV-VLYLKKGETKKK 601 + G +DP+V V + +G KK Sbjct: 395 ITGSSDPYVKVSLMCEGRRLKK 416 Score = 40.8 bits (94), Expect = 0.003 Identities = 38/131 (29%), Positives = 58/131 (44%), Gaps = 9/131 (6%) Frame = +2 Query: 26 LVGKSDPFAVLYIRPLSAKTKKSKTIN--NDLNPIWNEHYEFVV--EDSSTQHLTVKIYD 193 + G SDP+ + + + KK KT N LNP++NE F + E+ L + + D Sbjct: 395 ITGSSDPYVKVSLMCEGRRLKKRKTTTKKNTLNPVYNEAIIFDIPPENVDQVSLCIAVMD 454 Query: 194 DEGLQPSEIIGCARVDLSDIMPGKVKDVWLELVKDLEIQRDKKPRGQVHLELLYYP---- 361 + + +E+IG R L G +D W E+ + +KP H LL P Sbjct: 455 YDRVGHNEVIGVCRTGLD--AEGLGRDHWNEM-----LAYHRKPITHWH-PLLELPGRAT 506 Query: 362 -FDKQEGVSNP 391 FD Q S+P Sbjct: 507 SFDSQGSCSSP 517 Score = 34.7 bits (78), Expect = 0.22 Identities = 16/36 (44%), Positives = 22/36 (61%) Frame = +2 Query: 491 VLSVTVISAEDIPAMDVMGKADPFVVLYLKKGETKK 598 +L V +I A D+PA D G +DP+V +YL KK Sbjct: 247 LLVVKIIKALDLPAKDFTGTSDPYVKIYLLPDRKKK 282
>KPCB_RAT (P68403) Protein kinase C beta type (EC 2.7.11.13) (PKC-beta)| (PKC-B) Length = 670 Score = 47.8 bits (112), Expect = 2e-05 Identities = 30/94 (31%), Positives = 51/94 (54%), Gaps = 3/94 (3%) Frame = +2 Query: 32 GKSDPFAVLYI--RPLSAKTKKSKTINNDLNPIWNEHYEFVVEDS-STQHLTVKIYDDEG 202 G SDP+ L + P S +K+KTI LNP WNE + F +++S + L+V+I+D + Sbjct: 189 GLSDPYVKLKLIPDPKSESKQKTKTIKCSLNPEWNETFRFQLKESDKDRRLSVEIWDWDL 248 Query: 203 LQPSEIIGCARVDLSDIMPGKVKDVWLELVKDLE 304 ++ +G +S++ V D W +L+ E Sbjct: 249 TSRNDFMGSLSFGISELQKAGV-DGWFKLLSQEE 281
>KPCB_RABIT (P05772) Protein kinase C beta type (EC 2.7.11.13) (PKC-beta)| (PKC-B) Length = 670 Score = 47.8 bits (112), Expect = 2e-05 Identities = 30/94 (31%), Positives = 51/94 (54%), Gaps = 3/94 (3%) Frame = +2 Query: 32 GKSDPFAVLYI--RPLSAKTKKSKTINNDLNPIWNEHYEFVVEDS-STQHLTVKIYDDEG 202 G SDP+ L + P S +K+KTI LNP WNE + F +++S + L+V+I+D + Sbjct: 189 GLSDPYVKLKLIPDPKSESKQKTKTIKCSLNPEWNETFRFQLKESDKDRRLSVEIWDWDL 248 Query: 203 LQPSEIIGCARVDLSDIMPGKVKDVWLELVKDLE 304 ++ +G +S++ V D W +L+ E Sbjct: 249 TSRNDFMGSLSFGISELQKAGV-DGWFKLLSQEE 281
>RBF1_CAEEL (P41885) Rabphilin-1| Length = 1106 Score = 47.4 bits (111), Expect = 3e-05 Identities = 34/118 (28%), Positives = 58/118 (49%), Gaps = 10/118 (8%) Frame = +2 Query: 32 GKSDPFAVLYIRPLSAKTKK--SKTINNDLNPIWNE---HYEFVVEDSSTQHLTVKIYDD 196 G SDP+ ++ P + K K SKTI LNP WNE +Y +D + L V + D Sbjct: 861 GFSDPYVKFHLLPGNTKATKLTSKTIEKTLNPEWNEEMSYYGITEDDKEKKILRVTVLDR 920 Query: 197 EGLQPSEIIGCARVDLSDIMPGKVKDVWLELVKDLEI-----QRDKKPRGQVHLELLY 355 + + S+ +G R+ L + ++K L L L + + + + RG++++ L Y Sbjct: 921 DRI-GSDFLGETRIALKKLNDNEMKKFNLYLESALPVPQQTKEEENEDRGKINVGLQY 977 Score = 41.6 bits (96), Expect = 0.002 Identities = 23/69 (33%), Positives = 39/69 (56%), Gaps = 4/69 (5%) Frame = +2 Query: 32 GKSDPFAVLYIRPLSAKTKKSKTINND--LNPIWNEHYEFVV--EDSSTQHLTVKIYDDE 199 G SDP+ + + P+++K ++KT LNP WNE +FVV +D + L + +YD + Sbjct: 1001 GFSDPYCKVSLTPITSKAHRAKTSTKKRTLNPEWNEQLQFVVPFKDLPKKTLQIGVYDHD 1060 Query: 200 GLQPSEIIG 226 + + IG Sbjct: 1061 LGKHDDYIG 1069 Score = 30.0 bits (66), Expect = 5.3 Identities = 14/34 (41%), Positives = 22/34 (64%) Frame = +2 Query: 494 LSVTVISAEDIPAMDVMGKADPFVVLYLKKGETK 595 L + +I A+++ AMD G +DP+V +L G TK Sbjct: 844 LKMHLIRAKNLKAMDSNGFSDPYVKFHLLPGNTK 877
>SYT10_PONPY (Q5RCK6) Synaptotagmin-10 (Synaptotagmin X) (SytX)| Length = 523 Score = 47.4 bits (111), Expect = 3e-05 Identities = 46/202 (22%), Positives = 82/202 (40%), Gaps = 8/202 (3%) Frame = +2 Query: 20 RXLVGKSDPFAVLYIRPLSAKTKKSKTINNDLNPIWNEHYEFVV--EDSSTQHLTVKIYD 193 + G SDP+ +Y+ P K +++ LNP+++E ++F V + S + L +YD Sbjct: 261 KDFTGTSDPYVKMYLLPDRKKKFQTRVHRKTLNPLFDETFQFPVAYDQLSNRKLHFSVYD 320 Query: 194 DEGLQPSEIIGCARVD----LSDIMPGKVKDVWLELVKDLEIQRDKK-PRGQVHLELLYY 358 + ++IG +D +SD+ + VW KD+ + G++ L Y Sbjct: 321 FDRFSRHDMIGEVILDNLFEVSDL--SREATVW----KDIHCATTESIDLGEIMFSLCYL 374 Query: 359 PFDKQEGVSNPFASQIQLTSLEKVLKTESNGYDVNQRKNVITRGVLSVTVISAEDIPAMD 538 P T G +++TVI ++ AMD Sbjct: 375 P----------------------------------------TAGRMTLTVIKCRNLKAMD 394 Query: 539 VMGKADPFV-VLYLKKGETKKK 601 + G +DP+V V + +G KK Sbjct: 395 ITGSSDPYVKVSLMCEGRRLKK 416 Score = 40.0 bits (92), Expect = 0.005 Identities = 27/93 (29%), Positives = 46/93 (49%), Gaps = 4/93 (4%) Frame = +2 Query: 26 LVGKSDPFAVLYIRPLSAKTKKSKTIN--NDLNPIWNEHYEFVV--EDSSTQHLTVKIYD 193 + G SDP+ + + + KK KT N LNP++NE F + E+ L++ + D Sbjct: 395 ITGSSDPYVKVSLMCEGRRLKKRKTTTKKNTLNPVYNEAIIFDIPPENVDQVSLSIAVMD 454 Query: 194 DEGLQPSEIIGCARVDLSDIMPGKVKDVWLELV 292 + + +E+IG R L G +D W E++ Sbjct: 455 YDRVGHNEVIGVCRTGLD--AEGLGRDHWNEML 485 Score = 34.7 bits (78), Expect = 0.22 Identities = 16/36 (44%), Positives = 22/36 (61%) Frame = +2 Query: 491 VLSVTVISAEDIPAMDVMGKADPFVVLYLKKGETKK 598 +L V +I A D+PA D G +DP+V +YL KK Sbjct: 247 LLVVKIIKALDLPAKDFTGTSDPYVKMYLLPDRKKK 282
>SYT10_HUMAN (Q6XYQ8) Synaptotagmin-10 (Synaptotagmin X) (SytX)| Length = 523 Score = 47.4 bits (111), Expect = 3e-05 Identities = 46/202 (22%), Positives = 82/202 (40%), Gaps = 8/202 (3%) Frame = +2 Query: 20 RXLVGKSDPFAVLYIRPLSAKTKKSKTINNDLNPIWNEHYEFVV--EDSSTQHLTVKIYD 193 + G SDP+ +Y+ P K +++ LNP+++E ++F V + S + L +YD Sbjct: 261 KDFTGTSDPYVKMYLLPDRKKKFQTRVHRKTLNPLFDETFQFPVAYDQLSNRKLHFSVYD 320 Query: 194 DEGLQPSEIIGCARVD----LSDIMPGKVKDVWLELVKDLEIQRDKK-PRGQVHLELLYY 358 + ++IG +D +SD+ + VW KD+ + G++ L Y Sbjct: 321 FDRFSRHDMIGEVILDNLFEVSDL--SREATVW----KDIHCATTESIDLGEIMFSLCYL 374 Query: 359 PFDKQEGVSNPFASQIQLTSLEKVLKTESNGYDVNQRKNVITRGVLSVTVISAEDIPAMD 538 P T G +++TVI ++ AMD Sbjct: 375 P----------------------------------------TAGRMTLTVIKCRNLKAMD 394 Query: 539 VMGKADPFV-VLYLKKGETKKK 601 + G +DP+V V + +G KK Sbjct: 395 ITGSSDPYVKVSLMCEGRRLKK 416 Score = 40.0 bits (92), Expect = 0.005 Identities = 27/93 (29%), Positives = 46/93 (49%), Gaps = 4/93 (4%) Frame = +2 Query: 26 LVGKSDPFAVLYIRPLSAKTKKSKTIN--NDLNPIWNEHYEFVV--EDSSTQHLTVKIYD 193 + G SDP+ + + + KK KT N LNP++NE F + E+ L++ + D Sbjct: 395 ITGSSDPYVKVSLMCEGRRLKKRKTTTKKNTLNPVYNEAIIFDIPPENVDQVSLSIAVMD 454 Query: 194 DEGLQPSEIIGCARVDLSDIMPGKVKDVWLELV 292 + + +E+IG R L G +D W E++ Sbjct: 455 YDRVGHNEVIGVCRTGLD--AEGLGRDHWNEML 485 Score = 34.7 bits (78), Expect = 0.22 Identities = 16/36 (44%), Positives = 22/36 (61%) Frame = +2 Query: 491 VLSVTVISAEDIPAMDVMGKADPFVVLYLKKGETKK 598 +L V +I A D+PA D G +DP+V +YL KK Sbjct: 247 LLVVKIIKALDLPAKDFTGTSDPYVKMYLLPDRKKK 282
>PP16B_CUCMA (Q9ZT46) 16 kDa phloem protein 2| Length = 137 Score = 47.0 bits (110), Expect = 4e-05 Identities = 24/86 (27%), Positives = 44/86 (51%), Gaps = 3/86 (3%) Frame = +2 Query: 41 DPFAVLYIRPLSAKTKKSKTINNDLNPIWNEHYEFVVE---DSSTQHLTVKIYDDEGLQP 211 DP+A + + +K +K D PIWNE ++F+VE H+ K+ D + + Sbjct: 26 DPYAEINFKGQERMSKVAKNAGPD--PIWNEKFKFLVEYPGSGGDFHILFKVMDHDAIDG 83 Query: 212 SEIIGCARVDLSDIMPGKVKDVWLEL 289 + IG ++D+ +++ V+ W EL Sbjct: 84 DDYIGDVKIDVQNLLAEGVRKGWSEL 109
>KPCG_RAT (P63319) Protein kinase C gamma type (EC 2.7.11.13) (PKC-gamma)| Length = 697 Score = 46.6 bits (109), Expect = 5e-05 Identities = 29/106 (27%), Positives = 55/106 (51%), Gaps = 8/106 (7%) Frame = +2 Query: 11 GRTRXLV-----GKSDPFAVLYI--RPLSAKTKKSKTINNDLNPIWNEHYEFVVEDSSTQ 169 G R L+ G SDP+ L + P + +K+KT+ LNP+WNE + F ++ + Sbjct: 178 GEARNLIPMDPNGLSDPYVKLKLIPDPRNLTKQKTKTVKATLNPVWNETFVFNLKPGDVE 237 Query: 170 -HLTVKIYDDEGLQPSEIIGCARVDLSDIMPGKVKDVWLELVKDLE 304 L+V+++D + ++ +G +S+++ V D W +L+ E Sbjct: 238 RRLSVEVWDWDRTSRNDFMGAMSFGVSELLKAPV-DGWYKLLNQEE 282
>KPCG_MOUSE (P63318) Protein kinase C gamma type (EC 2.7.11.13) (PKC-gamma)| Length = 697 Score = 46.6 bits (109), Expect = 5e-05 Identities = 29/106 (27%), Positives = 55/106 (51%), Gaps = 8/106 (7%) Frame = +2 Query: 11 GRTRXLV-----GKSDPFAVLYI--RPLSAKTKKSKTINNDLNPIWNEHYEFVVEDSSTQ 169 G R L+ G SDP+ L + P + +K+KT+ LNP+WNE + F ++ + Sbjct: 178 GEARNLIPMDPNGLSDPYVKLKLIPDPRNLTKQKTKTVKATLNPVWNETFVFNLKPGDVE 237 Query: 170 -HLTVKIYDDEGLQPSEIIGCARVDLSDIMPGKVKDVWLELVKDLE 304 L+V+++D + ++ +G +S+++ V D W +L+ E Sbjct: 238 RRLSVEVWDWDRTSRNDFMGAMSFGVSELLKAPV-DGWYKLLNQEE 282
>KPCG_RABIT (P10829) Protein kinase C gamma type (EC 2.7.11.13) (PKC-gamma)| (PKC-delta) Length = 697 Score = 45.4 bits (106), Expect = 1e-04 Identities = 28/106 (26%), Positives = 55/106 (51%), Gaps = 8/106 (7%) Frame = +2 Query: 11 GRTRXLV-----GKSDPFAVLYI--RPLSAKTKKSKTINNDLNPIWNEHYEFVVEDSSTQ 169 G R L+ G SDP+ L + P + +K++T+ LNP+WNE + F ++ + Sbjct: 178 GEARNLIPMDPNGLSDPYVKLKLIPDPRNLTKQKTRTVKATLNPVWNETFVFNLKPGDVE 237 Query: 170 -HLTVKIYDDEGLQPSEIIGCARVDLSDIMPGKVKDVWLELVKDLE 304 L+V+++D + ++ +G +S+++ V D W +L+ E Sbjct: 238 RRLSVEVWDWDRTSRNDFMGAMSFGVSELLKAPV-DGWYKLLNQEE 282
>KPCG_HUMAN (P05129) Protein kinase C gamma type (EC 2.7.11.13) (PKC-gamma)| Length = 697 Score = 45.4 bits (106), Expect = 1e-04 Identities = 28/106 (26%), Positives = 55/106 (51%), Gaps = 8/106 (7%) Frame = +2 Query: 11 GRTRXLV-----GKSDPFAVLYI--RPLSAKTKKSKTINNDLNPIWNEHYEFVVEDSSTQ 169 G R L+ G SDP+ L + P + +K++T+ LNP+WNE + F ++ + Sbjct: 178 GEARNLIPMDPNGLSDPYVKLKLIPDPRNLTKQKTRTVKATLNPVWNETFVFNLKPGDVE 237 Query: 170 -HLTVKIYDDEGLQPSEIIGCARVDLSDIMPGKVKDVWLELVKDLE 304 L+V+++D + ++ +G +S+++ V D W +L+ E Sbjct: 238 RRLSVEVWDWDRTSRNDFMGAMSFGVSELLKAPV-DGWYKLLNQEE 282
>KPCG_BOVIN (P05128) Protein kinase C gamma type (EC 2.7.11.13) (PKC-gamma)| (Fragment) Length = 682 Score = 45.4 bits (106), Expect = 1e-04 Identities = 28/106 (26%), Positives = 55/106 (51%), Gaps = 8/106 (7%) Frame = +2 Query: 11 GRTRXLV-----GKSDPFAVLYI--RPLSAKTKKSKTINNDLNPIWNEHYEFVVEDSSTQ 169 G R L+ G SDP+ L + P + +K++T+ LNP+WNE + F ++ + Sbjct: 163 GEARNLIPMDPNGLSDPYVKLKLIPDPRNLTKQKTRTVKATLNPVWNETFVFNLKPGDVE 222 Query: 170 -HLTVKIYDDEGLQPSEIIGCARVDLSDIMPGKVKDVWLELVKDLE 304 L+V+++D + ++ +G +S+++ V D W +L+ E Sbjct: 223 RRLSVEVWDWDRTSRNDFMGAMSFGVSELLKAPV-DGWYKLLNQEE 267
>MYOF_HUMAN (Q9NZM1) Myoferlin (Fer-1-like protein 3)| Length = 2061 Score = 45.1 bits (105), Expect = 2e-04 Identities = 27/90 (30%), Positives = 47/90 (52%), Gaps = 3/90 (3%) Frame = +2 Query: 32 GKSDPFAVLYIRPLSAKTKKSKTINNDLNPIWNEHYEFVVED---SSTQHLTVKIYDDEG 202 GK DP + + KTKK ++N+LNP+WNE EF + + L + + D E Sbjct: 18 GKPDPIVSVIFKDEKKKTKK---VDNELNPVWNEILEFDLRGIPLDFSSSLGIIVKDFET 74 Query: 203 LQPSEIIGCARVDLSDIMPGKVKDVWLELV 292 + +++IG A V L D+ + + + +L+ Sbjct: 75 IGQNKLIGTATVALKDLTGDQSRSLPYKLI 104 Score = 29.6 bits (65), Expect = 6.9 Identities = 21/81 (25%), Positives = 39/81 (48%), Gaps = 3/81 (3%) Frame = +2 Query: 41 DPFAVLYIRPLSAKTKKSKTINNDLNPIWNEHYEFVVEDSST-QHLTVKIYDDEGLQPSE 217 DPF + + K + I + NP WN+ ++ S + + + IYD + L ++ Sbjct: 396 DPFVEV---SFAGKKVCTNIIEKNANPEWNQVVNLQIKFPSVCEKIKLTIYDWDRLTKND 452 Query: 218 IIGCARVDLSDIMP--GKVKD 274 ++G + LS I G+V+D Sbjct: 453 VVGTTYLHLSKIAASGGEVED 473
>KPCA_MOUSE (P20444) Protein kinase C alpha type (EC 2.7.11.13) (PKC-alpha)| (PKC-A) Length = 671 Score = 45.1 bits (105), Expect = 2e-04 Identities = 25/78 (32%), Positives = 46/78 (58%), Gaps = 3/78 (3%) Frame = +2 Query: 32 GKSDPFAVLYI--RPLSAKTKKSKTINNDLNPIWNEHYEFVVEDS-STQHLTVKIYDDEG 202 G SDP+ L + P + +K+KTI ++LNP WNE + F ++ S + L+V+I+D + Sbjct: 189 GLSDPYVKLKLIPDPKNESKQKTKTIRSNLNPQWNESFTFKLKPSDKDRRLSVEIWDWDR 248 Query: 203 LQPSEIIGCARVDLSDIM 256 ++ +G +S++M Sbjct: 249 TTRNDFMGSLSFGVSELM 266
>ITSN1_MOUSE (Q9Z0R4) Intersectin-1 (EH and SH3 domains protein 1)| Length = 1714 Score = 44.7 bits (104), Expect = 2e-04 Identities = 19/74 (25%), Positives = 41/74 (55%) Frame = +2 Query: 32 GKSDPFAVLYIRPLSAKTKKSKTINNDLNPIWNEHYEFVVEDSSTQHLTVKIYDDEGLQP 211 GKS+P+ + + ++ +KTI + LNP WN + +F + D + L + +++ + P Sbjct: 1608 GKSNPYCEV---TMGSQCHITKTIQDTLNPKWNSNCQFFIRDLEQEVLCITVFERDQFSP 1664 Query: 212 SEIIGCARVDLSDI 253 + +G + ++DI Sbjct: 1665 DDFLGRTEIRVADI 1678
>UNC13_CAEEL (P27715) Phorbol ester/diacylglycerol-binding protein unc-13| (Uncoordinated protein 13) Length = 2155 Score = 44.7 bits (104), Expect = 2e-04 Identities = 21/57 (36%), Positives = 37/57 (64%), Gaps = 1/57 (1%) Frame = +2 Query: 32 GKSDPFAVLYIRPLSAKTKK-SKTINNDLNPIWNEHYEFVVEDSSTQHLTVKIYDDE 199 GKSDP+ + KTK+ ++TI+ +LNP+WNE + F +ST + V+++D++ Sbjct: 1176 GKSDPYVTAQV----GKTKRRTRTIHQELNPVWNEKFHFECH-NSTDRIKVRVWDED 1227 Score = 30.4 bits (67), Expect = 4.1 Identities = 24/108 (22%), Positives = 50/108 (46%), Gaps = 1/108 (0%) Frame = +2 Query: 281 LELVKD-LEIQRDKKPRGQVHLELLYYPFDKQEGVSNPFASQIQLTSLEKVLKTESNGYD 457 + +++D ++IQ KP +++ FD E + ++ + LE K + Sbjct: 1105 VNVIRDRMKIQEQNKPEV---FQMIRTVFDVDENIQKETLKTVKASILEGSSKWSAK--- 1158 Query: 458 VNQRKNVITRGVLSVTVISAEDIPAMDVMGKADPFVVLYLKKGETKKK 601 +++TV+ A+ + A D GK+DP+V + G+TK++ Sbjct: 1159 ------------ITLTVLCAQGLIAKDKTGKSDPYVTAQV--GKTKRR 1192
>ITSN1_HUMAN (Q15811) Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17)| Length = 1721 Score = 44.7 bits (104), Expect = 2e-04 Identities = 19/74 (25%), Positives = 41/74 (55%) Frame = +2 Query: 32 GKSDPFAVLYIRPLSAKTKKSKTINNDLNPIWNEHYEFVVEDSSTQHLTVKIYDDEGLQP 211 GKS+P+ + + ++ +KTI + LNP WN + +F + D + L + +++ + P Sbjct: 1615 GKSNPYCEV---TMGSQCHITKTIQDTLNPKWNSNCQFFIRDLEQEVLCITVFERDQFSP 1671 Query: 212 SEIIGCARVDLSDI 253 + +G + ++DI Sbjct: 1672 DDFLGRTEIRVADI 1685
>DYSF_MOUSE (Q9ESD7) Dysferlin (Dystrophy-associated fer-1-like protein)| (Fer-1-like protein 1) Length = 2083 Score = 44.3 bits (103), Expect = 3e-04 Identities = 23/77 (29%), Positives = 43/77 (55%), Gaps = 3/77 (3%) Frame = +2 Query: 35 KSDPFAVLYIRPLSAKTKKSKTINNDLNPIWNEHYEFVVED---SSTQHLTVKIYDDEGL 205 +SDP A L R + K++K I N +NP+WNE +E+ ++ + L V + D E + Sbjct: 20 RSDPVASLIFRGVK---KRTKVIKNSVNPVWNEGFEWDLKGIPLDQSSELLVVVKDHETM 76 Query: 206 QPSEIIGCARVDLSDIM 256 + +G A++ L +++ Sbjct: 77 GRNRFLGEAKIPLQEVL 93
>KPCA_RAT (P05696) Protein kinase C alpha type (EC 2.7.11.13) (PKC-alpha)| (PKC-A) Length = 671 Score = 44.3 bits (103), Expect = 3e-04 Identities = 25/78 (32%), Positives = 45/78 (57%), Gaps = 3/78 (3%) Frame = +2 Query: 32 GKSDPFAVLYI--RPLSAKTKKSKTINNDLNPIWNEHYEFVVEDS-STQHLTVKIYDDEG 202 G SDP+ L + P + +K+KTI + LNP WNE + F ++ S + L+V+I+D + Sbjct: 189 GLSDPYVKLKLIPDPKNESKQKTKTIRSTLNPQWNESFTFKLKPSDKDRRLSVEIWDWDR 248 Query: 203 LQPSEIIGCARVDLSDIM 256 ++ +G +S++M Sbjct: 249 TTRNDFMGSLSFGVSELM 266
>KPCA_RABIT (P10102) Protein kinase C alpha type (EC 2.7.11.13) (PKC-alpha)| (PKC-A) Length = 671 Score = 44.3 bits (103), Expect = 3e-04 Identities = 25/78 (32%), Positives = 45/78 (57%), Gaps = 3/78 (3%) Frame = +2 Query: 32 GKSDPFAVLYI--RPLSAKTKKSKTINNDLNPIWNEHYEFVVEDS-STQHLTVKIYDDEG 202 G SDP+ L + P + +K+KTI + LNP WNE + F ++ S + L+V+I+D + Sbjct: 189 GLSDPYVKLKLIPDPKNESKQKTKTIRSTLNPQWNESFTFKLKPSDKDRRLSVEIWDWDR 248 Query: 203 LQPSEIIGCARVDLSDIM 256 ++ +G +S++M Sbjct: 249 TTRNDFMGSLSFGVSELM 266
>KPCA_HUMAN (P17252) Protein kinase C alpha type (EC 2.7.11.13) (PKC-alpha)| (PKC-A) Length = 671 Score = 44.3 bits (103), Expect = 3e-04 Identities = 25/78 (32%), Positives = 45/78 (57%), Gaps = 3/78 (3%) Frame = +2 Query: 32 GKSDPFAVLYI--RPLSAKTKKSKTINNDLNPIWNEHYEFVVEDS-STQHLTVKIYDDEG 202 G SDP+ L + P + +K+KTI + LNP WNE + F ++ S + L+V+I+D + Sbjct: 189 GLSDPYVKLKLIPDPKNESKQKTKTIRSTLNPQWNESFTFKLKPSDKDRRLSVEIWDWDR 248 Query: 203 LQPSEIIGCARVDLSDIM 256 ++ +G +S++M Sbjct: 249 TTRNDFMGSLSFGVSELM 266
>SYT6_RAT (Q62746) Synaptotagmin-6 (Synaptotagmin VI) (SytVI)| Length = 511 Score = 43.9 bits (102), Expect = 4e-04 Identities = 43/194 (22%), Positives = 77/194 (39%), Gaps = 4/194 (2%) Frame = +2 Query: 32 GKSDPFAVLYIRPLSAKTKKSKTINNDLNPIWNEHYEFVV--EDSSTQHLTVKIYDDEGL 205 G SDP+ +Y+ P +++ LNP ++E++ F V E+ + + L + ++D + Sbjct: 264 GSSDPYVKIYLLPDRKCKLQTRVHRKTLNPTFDENFHFPVPYEELADRKLHLSVFDFDRF 323 Query: 206 QPSEIIGCARVDLSDIMPGKVKDVWLELVKDLEIQRDKK-PRGQVHLELLYYPFDKQEGV 382 ++IG V L ++ + KD++ + G++ L Y P Sbjct: 324 SRHDMIG--EVILDNLFEASDLSRETSIWKDIQYATSESVDLGEIMFSLCYLP------- 374 Query: 383 SNPFASQIQLTSLEKVLKTESNGYDVNQRKNVITRGVLSVTVISAEDIPAMDVMGKADPF 562 T G L++TVI ++ AMD+ G +DP+ Sbjct: 375 ---------------------------------TAGRLTLTVIKCRNLKAMDITGYSDPY 401 Query: 563 V-VLYLKKGETKKK 601 V V L G KK Sbjct: 402 VKVSLLCDGRRLKK 415 Score = 41.6 bits (96), Expect = 0.002 Identities = 29/93 (31%), Positives = 47/93 (50%), Gaps = 4/93 (4%) Frame = +2 Query: 26 LVGKSDPFAVLYIRPLSAKTKKSKTI--NNDLNPIWNEHYEFVV--EDSSTQHLTVKIYD 193 + G SDP+ + + + KK KT N LNP++NE F + E+ L + + D Sbjct: 394 ITGYSDPYVKVSLLCDGRRLKKKKTTIKKNTLNPVYNEAIIFDIPPENMDQVSLLISVMD 453 Query: 194 DEGLQPSEIIGCARVDLSDIMPGKVKDVWLELV 292 + + +EIIG RV +S G +D W E++ Sbjct: 454 YDRVGHNEIIGVCRVGIS--AEGLGRDHWNEML 484 Score = 32.0 bits (71), Expect = 1.4 Identities = 13/28 (46%), Positives = 19/28 (67%) Frame = +2 Query: 494 LSVTVISAEDIPAMDVMGKADPFVVLYL 577 L V ++ A D+PA D G +DP+V +YL Sbjct: 247 LIVRILKAFDLPAKDFCGSSDPYVKIYL 274
>SYT6_MOUSE (Q9R0N8) Synaptotagmin-6 (Synaptotagmin VI) (SytVI)| Length = 511 Score = 43.9 bits (102), Expect = 4e-04 Identities = 43/194 (22%), Positives = 77/194 (39%), Gaps = 4/194 (2%) Frame = +2 Query: 32 GKSDPFAVLYIRPLSAKTKKSKTINNDLNPIWNEHYEFVV--EDSSTQHLTVKIYDDEGL 205 G SDP+ +Y+ P +++ LNP ++E++ F V E+ + + L + ++D + Sbjct: 264 GSSDPYVKIYLLPDRKCKLQTRVHRKTLNPTFDENFHFPVPYEELADRKLHLSVFDFDRF 323 Query: 206 QPSEIIGCARVDLSDIMPGKVKDVWLELVKDLEIQRDKK-PRGQVHLELLYYPFDKQEGV 382 ++IG V L ++ + KD++ + G++ L Y P Sbjct: 324 SRHDMIG--EVILDNLFEASDLSRETSIWKDIQYATSESVDLGEIMFSLCYLP------- 374 Query: 383 SNPFASQIQLTSLEKVLKTESNGYDVNQRKNVITRGVLSVTVISAEDIPAMDVMGKADPF 562 T G L++TVI ++ AMD+ G +DP+ Sbjct: 375 ---------------------------------TAGRLTLTVIKCRNLKAMDITGYSDPY 401 Query: 563 V-VLYLKKGETKKK 601 V V L G KK Sbjct: 402 VKVSLLCDGRRLKK 415 Score = 40.4 bits (93), Expect = 0.004 Identities = 28/93 (30%), Positives = 47/93 (50%), Gaps = 4/93 (4%) Frame = +2 Query: 26 LVGKSDPFAVLYIRPLSAKTKKSKTI--NNDLNPIWNEHYEFVV--EDSSTQHLTVKIYD 193 + G SDP+ + + + KK KT N LNP++NE F + E+ L + + D Sbjct: 394 ITGYSDPYVKVSLLCDGRRLKKKKTTIKKNTLNPVYNEAIIFDIPPENMDQVSLLISVMD 453 Query: 194 DEGLQPSEIIGCARVDLSDIMPGKVKDVWLELV 292 + + +EIIG RV ++ G +D W E++ Sbjct: 454 YDRVGHNEIIGVCRVGIN--AEGLGRDHWNEML 484 Score = 32.0 bits (71), Expect = 1.4 Identities = 13/28 (46%), Positives = 19/28 (67%) Frame = +2 Query: 494 LSVTVISAEDIPAMDVMGKADPFVVLYL 577 L V ++ A D+PA D G +DP+V +YL Sbjct: 247 LIVRILKAFDLPAKDFCGSSDPYVKIYL 274
>SYT6_HUMAN (Q5T7P8) Synaptotagmin-6 (Synaptotagmin VI) (SytVI)| Length = 510 Score = 43.9 bits (102), Expect = 4e-04 Identities = 43/194 (22%), Positives = 77/194 (39%), Gaps = 4/194 (2%) Frame = +2 Query: 32 GKSDPFAVLYIRPLSAKTKKSKTINNDLNPIWNEHYEFVV--EDSSTQHLTVKIYDDEGL 205 G SDP+ +Y+ P +++ LNP ++E++ F V E+ + + L + ++D + Sbjct: 263 GSSDPYVKIYLLPDRKCKLQTRVHRKTLNPTFDENFHFPVPYEELADRKLHLSVFDFDRF 322 Query: 206 QPSEIIGCARVDLSDIMPGKVKDVWLELVKDLEIQRDKK-PRGQVHLELLYYPFDKQEGV 382 ++IG V L ++ + KD++ + G++ L Y P Sbjct: 323 SRHDMIG--EVILDNLFEASDLSRETSIWKDIQYATSESVDLGEIMFSLCYLP------- 373 Query: 383 SNPFASQIQLTSLEKVLKTESNGYDVNQRKNVITRGVLSVTVISAEDIPAMDVMGKADPF 562 T G L++TVI ++ AMD+ G +DP+ Sbjct: 374 ---------------------------------TAGRLTLTVIKCRNLKAMDITGYSDPY 400 Query: 563 V-VLYLKKGETKKK 601 V V L G KK Sbjct: 401 VKVSLLCDGRRLKK 414 Score = 40.4 bits (93), Expect = 0.004 Identities = 28/93 (30%), Positives = 47/93 (50%), Gaps = 4/93 (4%) Frame = +2 Query: 26 LVGKSDPFAVLYIRPLSAKTKKSKTI--NNDLNPIWNEHYEFVV--EDSSTQHLTVKIYD 193 + G SDP+ + + + KK KT N LNP++NE F + E+ L + + D Sbjct: 393 ITGYSDPYVKVSLLCDGRRLKKKKTTIKKNTLNPVYNEAIIFDIPPENMDQVSLLISVMD 452 Query: 194 DEGLQPSEIIGCARVDLSDIMPGKVKDVWLELV 292 + + +EIIG RV ++ G +D W E++ Sbjct: 453 YDRVGHNEIIGVCRVGIT--AEGLGRDHWNEML 483 Score = 32.0 bits (71), Expect = 1.4 Identities = 13/28 (46%), Positives = 19/28 (67%) Frame = +2 Query: 494 LSVTVISAEDIPAMDVMGKADPFVVLYL 577 L V ++ A D+PA D G +DP+V +YL Sbjct: 246 LIVRILKAFDLPAKDFCGSSDPYVKIYL 273
>RASL2_HUMAN (O43374) Ras GTPase-activating protein 4 (RasGAP-activating-like| protein 2) (Calcium-promoted Ras inactivator) Length = 803 Score = 43.5 bits (101), Expect = 5e-04 Identities = 25/108 (23%), Positives = 54/108 (50%), Gaps = 2/108 (1%) Frame = +2 Query: 32 GKSDPFAVLYIRPLSAKTKKSKTINNDLNPIWNEHYEFVVEDSSTQHLTVKIYDDEGLQP 211 G SDPF + + +T+++ + P WNE +EF +++ + + L V+ +D + + Sbjct: 152 GTSDPFVRVRYK---GRTRETSIVKKSCYPRWNETFEFELQEGAMEALCVEAWDWDLVSR 208 Query: 212 SEIIGCARVDLSDIMPGKVKDVWLELVKDLEIQR--DKKPRGQVHLEL 349 ++ +G +D+ + + ++ W L D R D+ G + LE+ Sbjct: 209 NDFLGKVVIDVQRLRVVQQEEGWFRLQPDQSKSRRHDEGNLGSLQLEV 256
>KPC2_DROME (P13677) Protein kinase C, eye isozyme (EC 2.7.11.13) (PKC)| (dPKC53E(EY)) (Protein INAC) (Inactivation no after-potential C protein) (Photoreceptor-specific PKC) (Eye-PKC) Length = 700 Score = 43.1 bits (100), Expect = 6e-04 Identities = 26/94 (27%), Positives = 51/94 (54%), Gaps = 3/94 (3%) Frame = +2 Query: 32 GKSDPFAVLYIRP-LSAKTKK-SKTINNDLNPIWNEHYEFVVE-DSSTQHLTVKIYDDEG 202 G SDP+ + + P S +TKK +KTI +LNP++NE + F ++ + L ++++D + Sbjct: 225 GFSDPYIAVQMHPDRSGRTKKKTKTIQKNLNPVFNETFTFELQPQDRDKRLLIEVWDWDR 284 Query: 203 LQPSEIIGCARVDLSDIMPGKVKDVWLELVKDLE 304 ++ +G L ++ V D W + + +E Sbjct: 285 TSRNDFMGSFSFSLEELQKEPV-DGWYKFLSQVE 317
>KPC1_APLCA (Q16974) Calcium-dependent protein kinase C (EC 2.7.11.13) (APL I)| Length = 649 Score = 43.1 bits (100), Expect = 6e-04 Identities = 25/94 (26%), Positives = 53/94 (56%), Gaps = 3/94 (3%) Frame = +2 Query: 32 GKSDPFAVLYIRPLSA-KTK-KSKTINNDLNPIWNEHYEF-VVEDSSTQHLTVKIYDDEG 202 G +DP+ + + P A K K K+KTI LNP+WNE + + + +++ L+++++D + Sbjct: 174 GLADPYVKVKLIPYDAHKLKLKTKTIKASLNPVWNESFTVDIGPEDNSKRLSLEVWDWDR 233 Query: 203 LQPSEIIGCARVDLSDIMPGKVKDVWLELVKDLE 304 ++ +G +S+++ V+ W +L+ E Sbjct: 234 TSRNDFMGSLSFGISELIKSPVEG-WFKLLNQEE 266
>ERG3_ORYSA (Q7F9X0) Elicitor-responsive protein 3 (16 kDa phloem protein)| (RPP16) Length = 144 Score = 42.7 bits (99), Expect = 8e-04 Identities = 32/113 (28%), Positives = 54/113 (47%), Gaps = 1/113 (0%) Frame = +2 Query: 41 DPFAVLYIRPLSAKTKKSKTINNDLNPIWNEHYEFVVEDSSTQHLTVKIYDDEGLQPSEI 220 DP+AVL R S + K S +P WNE + F V ++T+ L +K+ D + + Sbjct: 26 DPYAVLKCR--SQEQKSSVASGKGSDPEWNETFMFSVTHNATE-LIIKLMDSDSGTDDDF 82 Query: 221 IGCARVDLSDI-MPGKVKDVWLELVKDLEIQRDKKPRGQVHLELLYYPFDKQE 376 +G A + L I G + +VK+ E RG++ + L + P D ++ Sbjct: 83 VGEATISLEAIYTEGSIPPTVYNVVKEEEY------RGEIKVGLTFTPEDDRD 129
>SYTL2_MOUSE (Q99N50) Synaptotagmin-like protein 2 (Exophilin-4)| Length = 950 Score = 42.4 bits (98), Expect = 0.001 Identities = 32/134 (23%), Positives = 58/134 (43%), Gaps = 8/134 (5%) Frame = +2 Query: 35 KSDPFAVLYIRPLSAKTKKSKT--INNDLNPIWNEHYEFVVEDS--STQHLTVKIYDDEG 202 +SDP+ Y+ P K K KT + LNP++NE + +E TQ L + ++ + Sbjct: 680 RSDPYVKTYLLPDKGKMGKKKTLVVKKTLNPVYNEILRYKIERQFLKTQKLNLSVWHRDT 739 Query: 203 LQPSEIIGCARVDLS----DIMPGKVKDVWLELVKDLEIQRDKKPRGQVHLELLYYPFDK 370 + + +G +DL D K + K + + + RG++ L L Y P + Sbjct: 740 FKRNSFLGEVELDLETWDWDSKQNKQLKWYPLKRKTAPVALETENRGEMKLALQYVP-EP 798 Query: 371 QEGVSNPFASQIQL 412 G P ++ + Sbjct: 799 SPGKKLPTTGEVHI 812
>SYTL2_HUMAN (Q9HCH5) Synaptotagmin-like protein 2 (Exophilin-4)| Length = 895 Score = 42.4 bits (98), Expect = 0.001 Identities = 33/117 (28%), Positives = 55/117 (47%), Gaps = 8/117 (6%) Frame = +2 Query: 35 KSDPFAVLYIRPLSAKTKKSKT--INNDLNPIWNEHYEFVVEDS--STQHLTVKIYDDEG 202 +SDP+ Y+ P K K KT + LNP++NE + +E TQ L + I+ + Sbjct: 625 RSDPYVKAYLLPDKGKMGKKKTLVVKKTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDT 684 Query: 203 LQPSEIIGCARVDLS--DIMPGKVKDV-WLELV-KDLEIQRDKKPRGQVHLELLYYP 361 + + +G +DL D + K + W L K + + + RG++ L L Y P Sbjct: 685 FKRNSFLGEVELDLETWDWDNKQNKQLRWYPLKRKTAPVALEAENRGEMKLALQYVP 741
>UN13A_HUMAN (Q9UPW8) Unc-13 homolog A (Munc13-1)| Length = 1703 Score = 42.4 bits (98), Expect = 0.001 Identities = 21/57 (36%), Positives = 36/57 (63%), Gaps = 1/57 (1%) Frame = +2 Query: 32 GKSDPFAVLYIRPLSAKTKK-SKTINNDLNPIWNEHYEFVVEDSSTQHLTVKIYDDE 199 G SDP+ + + KTKK +KTI +LNP+W E++ F +SS + V+++D++ Sbjct: 695 GSSDPYVTVQV----GKTKKRTKTIYGNLNPVWEENFHFECHNSS-DRIKVRVWDED 746 Score = 32.0 bits (71), Expect = 1.4 Identities = 14/36 (38%), Positives = 25/36 (69%) Frame = +2 Query: 494 LSVTVISAEDIPAMDVMGKADPFVVLYLKKGETKKK 601 +S+TV+ A+ + A D G +DP+V + + G+TKK+ Sbjct: 678 ISITVVCAQGLQAKDKTGSSDPYVTVQV--GKTKKR 711
>SYTL5_MOUSE (Q80T23) Synaptotagmin-like protein 5| Length = 753 Score = 42.0 bits (97), Expect = 0.001 Identities = 41/192 (21%), Positives = 83/192 (43%), Gaps = 5/192 (2%) Frame = +2 Query: 35 KSDPFAVLYIRPLSAKTKKSKT-INNDLNPIWNEHYEFVVEDS--STQHLTVKIYDDEGL 205 ++D + Y+ P ++ K KT I NP +NE ++ + + T+ L + ++ + Sbjct: 465 RTDAYVKSYLLPDKSRNNKRKTKIRTGTNPEFNETLKYTISHTQLETRTLQLSVWHYDRF 524 Query: 206 QPSEIIGCARVDLSDIMPGKVKDVWLELVKDLEIQRD--KKPRGQVHLELLYYPFDKQEG 379 + +G + D W L +E+ D + +G++ + L Y P +E Sbjct: 525 GRNSFLGEVEIAFDSWNFENPCDEWFVLQPKVELAPDISLQYKGELTIVLRYIP--PEEN 582 Query: 380 VSNPFASQIQLTSLEKVLKTESNGYDVNQRKNVITRGVLSVTVISAEDIPAMDVMGKADP 559 + P + + ++ K ES+ I+ G+L V + A+++ A+ G +D Sbjct: 583 LIFPAGQRQEKKIFKRGKKKESSS---------ISGGILEVFIKKAKNLTAVKSGGTSDS 633 Query: 560 FVVLYLKKGETK 595 FV YL + K Sbjct: 634 FVKGYLLPDDNK 645 Score = 35.4 bits (80), Expect = 0.13 Identities = 27/91 (29%), Positives = 41/91 (45%), Gaps = 6/91 (6%) Frame = +2 Query: 32 GKSDPFAVLYIRPLSAKTKKSKT--INNDLNPIWNEHYEF---VVEDSSTQHLTVKIYDD 196 G SD F Y+ P K K KT + +NP WN + F +D L + I+D Sbjct: 629 GTSDSFVKGYLLPDDNKATKHKTAVVKKSVNPEWNHTFIFSGLYPQDIKNACLELTIWDK 688 Query: 197 EGLQPSEIIGCARVDL-SDIMPGKVKDVWLE 286 E + +G R++ S + GK D W++ Sbjct: 689 EAFSSNVFLGGVRLNSGSGMSYGKTVD-WMD 718
>UN13B_HUMAN (O14795) Unc-13 homolog B (Munc13-2) (munc13)| Length = 1591 Score = 41.6 bits (96), Expect = 0.002 Identities = 21/57 (36%), Positives = 36/57 (63%), Gaps = 1/57 (1%) Frame = +2 Query: 32 GKSDPFAVLYIRPLSAKTKK-SKTINNDLNPIWNEHYEFVVEDSSTQHLTVKIYDDE 199 G SDP+ + + +KTKK +KTI +LNP+W E + F +SS + V+++D++ Sbjct: 619 GSSDPYVTVQV----SKTKKRTKTIFGNLNPVWEEKFHFECHNSS-DRIKVRVWDED 670 Score = 30.0 bits (66), Expect = 5.3 Identities = 13/36 (36%), Positives = 24/36 (66%) Frame = +2 Query: 494 LSVTVISAEDIPAMDVMGKADPFVVLYLKKGETKKK 601 +++TV+ A+ + A D G +DP+V + + K TKK+ Sbjct: 602 ITITVVCAQGLQAKDKTGSSDPYVTVQVSK--TKKR 635
>SYTL1_MOUSE (Q99N80) Synaptotagmin-like protein 1 (Exophilin-7)| Length = 567 Score = 41.6 bits (96), Expect = 0.002 Identities = 33/118 (27%), Positives = 53/118 (44%), Gaps = 3/118 (2%) Frame = +2 Query: 35 KSDPFAVLYIRPLSAKTKKSKTINNDLNPIWNEHYEFVVE--DSSTQHLTVKIYDDEGLQ 208 +SDP+ Y+ P +K+ +LNPI+NE V+ D + L++ ++ E L Sbjct: 305 RSDPYVKSYLLPDKQSKRKTSVKKRNLNPIFNETLRHSVQQADLPGRVLSLSVWHRESLG 364 Query: 209 PSEIIGCARVDLSDIMPGKVKDVWLELVKDLEIQRDKKP-RGQVHLELLYYPFDKQEG 379 + +G V L D + WL L + D+ P RG + L L Y P + G Sbjct: 365 RNIFLGEVEVPL-DTWNWDSEATWLPLQPRVPPSPDELPSRGLLSLSLKYVPAGSEGG 421
>YMH2_YEAST (Q03640) Hypothetical 171.1 kDa protein in RPL6A-DAK1 intergenic| region Length = 1545 Score = 41.2 bits (95), Expect = 0.002 Identities = 43/172 (25%), Positives = 69/172 (40%), Gaps = 13/172 (7%) Frame = +2 Query: 17 TRXLVGKSDPFAVLYIRPLSAKTKKSKTINNDLNPIWNEHYEFVVEDSSTQHLTVKIYDD 196 T + G P A L+I K K +T+ P WNE E +V S +KI+DD Sbjct: 678 TSSMTGSLSPCAELFID--GQKVKSYRTLRRINEPSWNETIEVLVPSKSNSKFVLKIFDD 735 Query: 197 EGLQPSEIIGCARVDLSDIMPGKVKDVWLELVKDLEIQRDKKPRGQVHLELLYY------ 358 + +I L DIM D E VK P+G ++L++ + Sbjct: 736 R-MNGKALICEYSSSLDDIM--TTLDTAQEFVKG-------SPQGDIYLDVSWKSIEMTG 785 Query: 359 PFDKQEGVSNPFASQIQLTSLEKVLKTESNG-------YDVNQRKNVITRGV 493 F VS P I+L + ++K + +G Y V+ + V+ + + Sbjct: 786 AFAAANSVSEPIGC-IKLDVKDAIIKGDLSGVGDVDPYYTVSLNRRVLYKSI 836 Score = 40.0 bits (92), Expect = 0.005 Identities = 30/116 (25%), Positives = 52/116 (44%) Frame = +2 Query: 32 GKSDPFAVLYIRPLSAKTKKSKTINNDLNPIWNEHYEFVVEDSSTQHLTVKIYDDEGLQP 211 G SDPF +++ K KS L+P+WNE + + S + + D + Sbjct: 1153 GYSDPFVHIFVN--DKKVFKSNIKKKTLDPVWNEDAKIPILSRSKNQVIFNVLDWDRAGD 1210 Query: 212 SEIIGCARVDLSDIMPGKVKDVWLELVKDLEIQRDKKPRGQVHLELLYYPFDKQEG 379 ++ +G A +D+S + GK + L +L Q K +G + E + FD +G Sbjct: 1211 NDDLGQASLDVSSLEVGKTYNWNL----NLNTQGSIKLQGSFNPEYIKPSFDIVKG 1262
>UN13B_RAT (Q62769) Unc-13 homolog B (Munc13-2)| Length = 1622 Score = 41.2 bits (95), Expect = 0.002 Identities = 21/57 (36%), Positives = 35/57 (61%), Gaps = 1/57 (1%) Frame = +2 Query: 32 GKSDPFAVLYIRPLSAKTKK-SKTINNDLNPIWNEHYEFVVEDSSTQHLTVKIYDDE 199 G SDP+ + + KTKK +KTI +LNP+W E + F +SS + V+++D++ Sbjct: 632 GSSDPYVTVQV----GKTKKRTKTIFGNLNPVWEEKFHFECHNSS-DRIKVRVWDED 683 Score = 30.8 bits (68), Expect = 3.1 Identities = 13/36 (36%), Positives = 25/36 (69%) Frame = +2 Query: 494 LSVTVISAEDIPAMDVMGKADPFVVLYLKKGETKKK 601 +++TV+ A+ + A D G +DP+V + + G+TKK+ Sbjct: 615 ITITVVCAQGLQAKDKTGSSDPYVTVQV--GKTKKR 648
>UN13A_RAT (Q62768) Unc-13 homolog A (Munc13-1)| Length = 1735 Score = 41.2 bits (95), Expect = 0.002 Identities = 21/57 (36%), Positives = 35/57 (61%), Gaps = 1/57 (1%) Frame = +2 Query: 32 GKSDPFAVLYIRPLSAKTKK-SKTINNDLNPIWNEHYEFVVEDSSTQHLTVKIYDDE 199 G SDP+ + + KTKK +KTI +LNP+W E++ F +SS + V++ D++ Sbjct: 708 GSSDPYVTVQV----GKTKKRTKTIYGNLNPVWEENFHFECHNSS-DRIKVRVLDED 759 Score = 32.0 bits (71), Expect = 1.4 Identities = 14/36 (38%), Positives = 25/36 (69%) Frame = +2 Query: 494 LSVTVISAEDIPAMDVMGKADPFVVLYLKKGETKKK 601 +S+TV+ A+ + A D G +DP+V + + G+TKK+ Sbjct: 691 ISITVVCAQGLQAKDKTGSSDPYVTVQV--GKTKKR 724
>SYTL5_HUMAN (Q8TDW5) Synaptotagmin-like protein 5| Length = 730 Score = 41.2 bits (95), Expect = 0.002 Identities = 43/192 (22%), Positives = 82/192 (42%), Gaps = 5/192 (2%) Frame = +2 Query: 35 KSDPFAVLYIRPLSAKTKKSKT-INNDLNPIWNEHYEFVVEDS--STQHLTVKIYDDEGL 205 ++D + Y+ P ++ K KT I NP +NE ++ + + T+ L + ++ + Sbjct: 442 RTDAYVKSYLLPDKSRNNKRKTKIRTGTNPEFNETLKYTISHTQLETRTLQLSVWHYDRF 501 Query: 206 QPSEIIGCARVDLSDIMPGKVKDVWLELVKDLEIQRD--KKPRGQVHLELLYYPFDKQEG 379 + +G + D W L +E D + +G++ + L Y P +E Sbjct: 502 GRNSFLGEVEIPFDSWNFENPTDEWFVLQPKVEFAPDIGLQYKGELTVVLRYIP--PEEN 559 Query: 380 VSNPFASQIQLTSLEKVLKTESNGYDVNQRKNVITRGVLSVTVISAEDIPAMDVMGKADP 559 + P + +K K ES VI+ G+L V + A+++ A+ G +D Sbjct: 560 LMLPPEQLQGNKTFKKGKKKES---------PVISGGILEVFIKEAKNLTAVKSGGTSDS 610 Query: 560 FVVLYLKKGETK 595 FV YL ++K Sbjct: 611 FVKGYLLPDDSK 622 Score = 36.2 bits (82), Expect = 0.074 Identities = 28/91 (30%), Positives = 42/91 (46%), Gaps = 6/91 (6%) Frame = +2 Query: 32 GKSDPFAVLYIRPLSAKTKKSKT--INNDLNPIWNEHYEFV---VEDSSTQHLTVKIYDD 196 G SD F Y+ P +K K KT I +NP WN + F +D L + I+D Sbjct: 606 GTSDSFVKGYLLPDDSKATKHKTLVIKKSVNPQWNHTFMFSGIHPQDIKNVCLELTIWDK 665 Query: 197 EGLQPSEIIGCARVDL-SDIMPGKVKDVWLE 286 E + +G R++ S + GK D W++ Sbjct: 666 EAFSSNIFLGGVRLNSGSGVSHGKNVD-WMD 695
>SYTL1_HUMAN (Q8IYJ3) Synaptotagmin-like protein 1 (Exophilin-7) (JFC1 protein)| (SB146) Length = 562 Score = 41.2 bits (95), Expect = 0.002 Identities = 34/127 (26%), Positives = 56/127 (44%), Gaps = 3/127 (2%) Frame = +2 Query: 35 KSDPFAVLYIRPLSAKTKKSKTINNDLNPIWNEHYEFVVEDSSTQH--LTVKIYDDEGLQ 208 +SDP+ Y+ P +K+ +LNP++NE + V + Q L++ ++ E L Sbjct: 300 RSDPYVKSYLLPDKQSKRKTAVKKRNLNPVFNETLRYSVPQAELQGRVLSLSVWHRESLG 359 Query: 209 PSEIIGCARVDLSDIMPGKVKDVWLELVKDLEIQRDKKP-RGQVHLELLYYPFDKQEGVS 385 + +G V L D + WL L + D P RG + L L Y P EG Sbjct: 360 RNIFLGEVEVPL-DTWDWGSEPTWLPLQPRVPPSPDDLPSRGLLALSLKYVPAG-SEGAG 417 Query: 386 NPFASQI 406 P + ++ Sbjct: 418 LPPSGEL 424
>UN13B_MOUSE (Q9Z1N9) Unc-13 homolog B (Munc13-2) (munc13)| Length = 1591 Score = 41.2 bits (95), Expect = 0.002 Identities = 21/57 (36%), Positives = 35/57 (61%), Gaps = 1/57 (1%) Frame = +2 Query: 32 GKSDPFAVLYIRPLSAKTKK-SKTINNDLNPIWNEHYEFVVEDSSTQHLTVKIYDDE 199 G SDP+ + + KTKK +KTI +LNP+W E + F +SS + V+++D++ Sbjct: 619 GSSDPYVTVQV----GKTKKRTKTIFGNLNPVWEEKFHFECHNSS-DRIKVRVWDED 670 Score = 30.8 bits (68), Expect = 3.1 Identities = 13/36 (36%), Positives = 25/36 (69%) Frame = +2 Query: 494 LSVTVISAEDIPAMDVMGKADPFVVLYLKKGETKKK 601 +++TV+ A+ + A D G +DP+V + + G+TKK+ Sbjct: 602 ITITVVCAQGLQAKDKTGSSDPYVTVQV--GKTKKR 635
>ITSN2_HUMAN (Q9NZM3) Intersectin-2 (SH3 domain-containing protein 1B) (SH3P18)| (SH3P18-like WASP-associated protein) Length = 1696 Score = 40.8 bits (94), Expect = 0.003 Identities = 18/74 (24%), Positives = 41/74 (55%) Frame = +2 Query: 32 GKSDPFAVLYIRPLSAKTKKSKTINNDLNPIWNEHYEFVVEDSSTQHLTVKIYDDEGLQP 211 GKS+P+ + + +++ ++TI + LNP WN + +F ++D L + ++D + P Sbjct: 1587 GKSNPYCEI---SMGSQSYTTRTIQDTLNPKWNFNCQFFIKDLYQDVLCLTLFDRDQFSP 1643 Query: 212 SEIIGCARVDLSDI 253 + +G + ++ I Sbjct: 1644 DDFLGRTEIPVAKI 1657
>NED4L_MOUSE (Q8CFI0) E3 ubiquitin-protein ligase NEDD4-like protein (EC| 6.3.2.-) (Nedd4-2) (NEDD4.2) Length = 1004 Score = 40.4 bits (93), Expect = 0.004 Identities = 35/124 (28%), Positives = 58/124 (46%), Gaps = 10/124 (8%) Frame = +2 Query: 20 RXLVGKSDPFAVLYIRPLSAKTK----KSKTINNDLNPIWNEHYEFVVEDSSTQHLTVKI 187 + + G SDP+ L + + ++KTI LNP WNE + F V + S L ++ Sbjct: 63 KDIFGASDPYVKLSLYVADENRELALVQTKTIKKTLNPKWNEEFYFRV-NPSNHRLLFEV 121 Query: 188 YDDEGLQPSEIIGCARVDLSDIMPGKVKDVWLE---LVKDLEIQ-RDKKPR--GQVHLEL 349 +D+ L + +G V LS + +D +E KD ++ R K R G + L++ Sbjct: 122 FDENRLTRDDFLGQVDVPLSHL---PTEDPTMERPYTFKDFLLRPRSHKSRVKGFLRLKM 178 Query: 350 LYYP 361 Y P Sbjct: 179 AYMP 182
>YNI7_YEAST (P48231) Hypothetical 132.5 kDa protein in TOP2-MKT1 intergenic| region Length = 1178 Score = 40.4 bits (93), Expect = 0.004 Identities = 25/77 (32%), Positives = 34/77 (44%), Gaps = 1/77 (1%) Frame = +2 Query: 32 GKSDPFAVLYIRPLSAKTK-KSKTINNDLNPIWNEHYEFVVEDSSTQHLTVKIYDDEGLQ 208 G SDP+ ++ S K+ LNP WNE V + +LT+ + D E Sbjct: 1002 GYSDPYVEFFLNEKSTSPFFKTAVQKKTLNPTWNESKTIEVSNRVNDYLTINVKDYESTN 1061 Query: 209 PSEIIGCARVDLSDIMP 259 + IG A V LS I P Sbjct: 1062 SNRSIGKAVVPLSTIDP 1078 Score = 39.3 bits (90), Expect = 0.009 Identities = 29/125 (23%), Positives = 55/125 (44%), Gaps = 2/125 (1%) Frame = +2 Query: 89 KSKTINNDLNPIWNEHYEFVVEDSSTQHLTVKIYDDEGLQPSEIIGCARVDLSDIMPGKV 268 K+K N NP+WNE +++ S T LT+ +YD + +G +L+ K+ Sbjct: 416 KTKVFKNSANPVWNESI-YILLQSFTDPLTIAVYDKRETLSDKKMGTVIFNLN-----KL 469 Query: 269 KDVWLELVKDLEIQRDKKPRGQVHLELLYYPFDKQEGVSNPFASQI--QLTSLEKVLKTE 442 + + R+ KP G++ +L ++P + + + N + T + K+ E Sbjct: 470 HANHYHKNEKVHFLRNSKPVGELTFDLRFFPTIEPKKLLNGDEEPLPDMNTGITKITIRE 529 Query: 443 SNGYD 457 G D Sbjct: 530 LKGLD 534
>NED4L_PONPY (Q5RBF2) E3 ubiquitin-protein ligase NEDD4-like protein (EC| 6.3.2.-) Length = 959 Score = 40.4 bits (93), Expect = 0.004 Identities = 35/124 (28%), Positives = 58/124 (46%), Gaps = 10/124 (8%) Frame = +2 Query: 20 RXLVGKSDPFAVLYIRPLSAKTK----KSKTINNDLNPIWNEHYEFVVEDSSTQHLTVKI 187 + + G SDP+ L + + ++KTI LNP WNE + F V + S L ++ Sbjct: 39 KDIFGASDPYVKLSLYVADENRELALVQTKTIKKTLNPKWNEEFYFRV-NPSNHRLLFEV 97 Query: 188 YDDEGLQPSEIIGCARVDLSDIMPGKVKDVWLE---LVKDLEIQ-RDKKPR--GQVHLEL 349 +D+ L + +G V LS + +D +E KD ++ R K R G + L++ Sbjct: 98 FDENRLTRDDFLGQVDVPLSHL---PTEDPTMERPYTFKDFLLRPRSHKSRVKGFLRLKM 154 Query: 350 LYYP 361 Y P Sbjct: 155 AYMP 158
>NED4L_HUMAN (Q96PU5) E3 ubiquitin-protein ligase NEDD4-like protein (EC| 6.3.2.-) (Nedd4-2) (NEDD4.2) Length = 975 Score = 40.4 bits (93), Expect = 0.004 Identities = 35/124 (28%), Positives = 58/124 (46%), Gaps = 10/124 (8%) Frame = +2 Query: 20 RXLVGKSDPFAVLYIRPLSAKTK----KSKTINNDLNPIWNEHYEFVVEDSSTQHLTVKI 187 + + G SDP+ L + + ++KTI LNP WNE + F V + S L ++ Sbjct: 35 KDIFGASDPYVKLSLYVADENRELALVQTKTIKKTLNPKWNEEFYFRV-NPSNHRLLFEV 93 Query: 188 YDDEGLQPSEIIGCARVDLSDIMPGKVKDVWLE---LVKDLEIQ-RDKKPR--GQVHLEL 349 +D+ L + +G V LS + +D +E KD ++ R K R G + L++ Sbjct: 94 FDENRLTRDDFLGQVDVPLSHL---PTEDPTMERPYTFKDFLLRPRSHKSRVKGFLRLKM 150 Query: 350 LYYP 361 Y P Sbjct: 151 AYMP 154
>PUB3_SCHPO (O14326) E3 ubiquitin--protein ligase pub3 (EC 6.3.2.-)| Length = 786 Score = 40.4 bits (93), Expect = 0.004 Identities = 20/60 (33%), Positives = 35/60 (58%) Frame = +2 Query: 20 RXLVGKSDPFAVLYIRPLSAKTKKSKTINNDLNPIWNEHYEFVVEDSSTQHLTVKIYDDE 199 R L + DPFA+L + +T +K I +NP WNE +E V+ SS ++++++D + Sbjct: 21 RDLFRQPDPFAILTVD--GEQTHTTKVIKKSVNPYWNEGFEVTVKPSSV--ISIRLFDQK 76
>KPCA_BOVIN (P04409) Protein kinase C alpha type (EC 2.7.11.13) (PKC-alpha)| (PKC-A) Length = 671 Score = 40.0 bits (92), Expect = 0.005 Identities = 23/78 (29%), Positives = 44/78 (56%), Gaps = 3/78 (3%) Frame = +2 Query: 32 GKSDPFAVLYI--RPLSAKTKKSKTINNDLNPIWNEHYEFVVEDS-STQHLTVKIYDDEG 202 G SDP+ L + P + +K+KTI + LNP W+E + F ++ S + L+ +I+D + Sbjct: 189 GLSDPYVKLKLIPDPKNESKQKTKTIRSTLNPRWDESFTFKLKPSDKDRRLSEEIWDWDR 248 Query: 203 LQPSEIIGCARVDLSDIM 256 ++ +G +S++M Sbjct: 249 TTRNDFMGSLSFGVSELM 266
>RASA3_HUMAN (Q14644) Ras GTPase-activating protein 3 (GAP1(IP4BP)) (Ins| P4-binding protein) Length = 834 Score = 40.0 bits (92), Expect = 0.005 Identities = 23/87 (26%), Positives = 42/87 (48%) Frame = +2 Query: 89 KSKTINNDLNPIWNEHYEFVVEDSSTQHLTVKIYDDEGLQPSEIIGCARVDLSDIMPGKV 268 ++K + L P + E + + S +HL+ I+D + + IIG + D+ Sbjct: 49 RTKIVEKSLCPFYGEDFYCEIP-RSFRHLSFYIFDRDVFRRDSIIGKVAIQKEDLQKYHN 107 Query: 269 KDVWLELVKDLEIQRDKKPRGQVHLEL 349 +D W +L + D + +G+VHLEL Sbjct: 108 RDTWFQL---QHVDADSEVQGKVHLEL 131
>RASA3_BOVIN (Q28013) Ras GTPase-activating protein 3 (GAP1(IP4BP)) (Ins| P4-binding protein) Length = 834 Score = 40.0 bits (92), Expect = 0.005 Identities = 23/87 (26%), Positives = 42/87 (48%) Frame = +2 Query: 89 KSKTINNDLNPIWNEHYEFVVEDSSTQHLTVKIYDDEGLQPSEIIGCARVDLSDIMPGKV 268 ++K + L P + E + + S +HL+ I+D + + IIG + D+ Sbjct: 49 RTKVVEKSLCPFYGEDFYCEIP-RSFRHLSFYIFDRDVFRRDSIIGKVAIKKEDLQKYHN 107 Query: 269 KDVWLELVKDLEIQRDKKPRGQVHLEL 349 +D W +L + D + +G+VHLEL Sbjct: 108 RDTWFQL---QHVDADSEVQGKVHLEL 131
>RASA3_MOUSE (Q60790) Ras GTPase-activating protein 3 (GAP1(IP4BP)) (Ins| P4-binding protein) (GapIII) Length = 834 Score = 39.7 bits (91), Expect = 0.007 Identities = 23/87 (26%), Positives = 42/87 (48%) Frame = +2 Query: 89 KSKTINNDLNPIWNEHYEFVVEDSSTQHLTVKIYDDEGLQPSEIIGCARVDLSDIMPGKV 268 ++K + L P + E + + S +HL+ I+D + + IIG + D+ Sbjct: 49 RTKIVEKSLCPFYGEDFYCEIP-RSFRHLSFYIFDRDVFRRDSIIGKVAIQKEDLQRYHN 107 Query: 269 KDVWLELVKDLEIQRDKKPRGQVHLEL 349 +D W +L + D + +G+VHLEL Sbjct: 108 RDTWFQL---QHVDADSEVQGKVHLEL 131
>SMUF1_HUMAN (Q9HCE7) Smad ubiquitination regulatory factor 1 (EC 6.3.2.-)| (Ubiquitin--protein ligase SMURF1) (Smad-specific E3 ubiquitin ligase 1) (hSMURF1) Length = 757 Score = 39.7 bits (91), Expect = 0.007 Identities = 20/69 (28%), Positives = 38/69 (55%), Gaps = 3/69 (4%) Frame = +2 Query: 41 DPFAVLYIRPLSAKTKKSKTINNDLNPIWNEHYEFVVEDSSTQHLTVKIYDDEGL---QP 211 DPFA + + S + + T+ N L+P WN+HY+ V T +T+ +++ + + Q Sbjct: 35 DPFAKIVVDG-SGQCHSTDTVKNTLDPKWNQHYDLYV--GKTDSITISVWNHKKIHKKQG 91 Query: 212 SEIIGCARV 238 + +GC R+ Sbjct: 92 AGFLGCVRL 100
>ITSN2_MOUSE (Q9Z0R6) Intersectin-2 (SH3 domain-containing protein 1B) (EH and SH3| domains protein 2) (EH domain and SH3 domain regulator of endocytosis 2) Length = 1658 Score = 39.7 bits (91), Expect = 0.007 Identities = 18/74 (24%), Positives = 41/74 (55%) Frame = +2 Query: 32 GKSDPFAVLYIRPLSAKTKKSKTINNDLNPIWNEHYEFVVEDSSTQHLTVKIYDDEGLQP 211 GKS+P+ + + +++ ++T+ + LNP WN + +F ++D L + ++D + P Sbjct: 1549 GKSNPYCEV---SMGSQSYTTRTLQDTLNPKWNFNCQFFIKDLYQDVLCLTMFDRDQFSP 1605 Query: 212 SEIIGCARVDLSDI 253 + +G V ++ I Sbjct: 1606 DDFLGRTEVPVAKI 1619
>SMUF1_MOUSE (Q9CUN6) Smad ubiquitination regulatory factor 1 (EC 6.3.2.-)| (Ubiquitin--protein ligase SMURF1) (Smad-specific E3 ubiquitin ligase 1) Length = 731 Score = 39.7 bits (91), Expect = 0.007 Identities = 20/69 (28%), Positives = 38/69 (55%), Gaps = 3/69 (4%) Frame = +2 Query: 41 DPFAVLYIRPLSAKTKKSKTINNDLNPIWNEHYEFVVEDSSTQHLTVKIYDDEGL---QP 211 DPFA + + S + + T+ N L+P WN+HY+ V T +T+ +++ + + Q Sbjct: 35 DPFAKIVVDG-SGQCHSTDTVKNTLDPKWNQHYDLYV--GKTDSITISVWNHKKIHKKQG 91 Query: 212 SEIIGCARV 238 + +GC R+ Sbjct: 92 AGFLGCVRL 100
>UN13C_HUMAN (Q8NB66) Unc-13 homolog C (Munc13-3) (Fragment)| Length = 1190 Score = 39.3 bits (90), Expect = 0.009 Identities = 17/56 (30%), Positives = 34/56 (60%) Frame = +2 Query: 32 GKSDPFAVLYIRPLSAKTKKSKTINNDLNPIWNEHYEFVVEDSSTQHLTVKIYDDE 199 G SDP+ + + +++KTI +LNP+W+E + F +ST + V+++D++ Sbjct: 215 GSSDPYVTVQV---GKNKRRTKTIFGNLNPVWDEKFYFECH-NSTDRIKVRVWDED 266 Score = 32.0 bits (71), Expect = 1.4 Identities = 12/36 (33%), Positives = 24/36 (66%) Frame = +2 Query: 494 LSVTVISAEDIPAMDVMGKADPFVVLYLKKGETKKK 601 +++TV+SA+ + A D G +DP+V + + K + + K Sbjct: 198 ITITVVSAQGLQAKDKTGSSDPYVTVQVGKNKRRTK 233
>DYSF_HUMAN (O75923) Dysferlin (Dystrophy-associated fer-1-like protein)| (Fer-1-like protein 1) Length = 2080 Score = 39.3 bits (90), Expect = 0.009 Identities = 20/62 (32%), Positives = 36/62 (58%), Gaps = 5/62 (8%) Frame = +2 Query: 86 KKSKTINNDLNPIWNEHYEF-----VVEDSSTQHLTVKIYDDEGLQPSEIIGCARVDLSD 250 K++K I N +NP+WNE +E+ ++ S H+ VK D E + + +G A+V L + Sbjct: 33 KRTKVIKNSVNPVWNEGFEWDLKGIPLDQGSELHVVVK--DHETMGRNRFLGEAKVPLRE 90 Query: 251 IM 256 ++ Sbjct: 91 VL 92
>UN13C_RAT (Q62770) Unc-13 homolog C (Munc13-3)| Length = 2204 Score = 39.3 bits (90), Expect = 0.009 Identities = 17/56 (30%), Positives = 34/56 (60%) Frame = +2 Query: 32 GKSDPFAVLYIRPLSAKTKKSKTINNDLNPIWNEHYEFVVEDSSTQHLTVKIYDDE 199 G SDP+ + + +++KTI +LNP+W+E + F +ST + V+++D++ Sbjct: 1229 GSSDPYVTVQV---GKNKRRTKTIFGNLNPVWDEKFYFECH-NSTDRIKVRVWDED 1280 Score = 32.0 bits (71), Expect = 1.4 Identities = 12/36 (33%), Positives = 24/36 (66%) Frame = +2 Query: 494 LSVTVISAEDIPAMDVMGKADPFVVLYLKKGETKKK 601 +++TV+SA+ + A D G +DP+V + + K + + K Sbjct: 1212 ITITVVSAQGLQAKDKTGSSDPYVTVQVGKNKRRTK 1247
>BAIP3_HUMAN (O94812) BAI1-associated protein 3 (BAP3)| Length = 1187 Score = 38.9 bits (89), Expect = 0.011 Identities = 18/45 (40%), Positives = 29/45 (64%), Gaps = 1/45 (2%) Frame = +2 Query: 68 PLSAKT-KKSKTINNDLNPIWNEHYEFVVEDSSTQHLTVKIYDDE 199 PL AK + ++ ++ LNP+W EH+ F +ED ST L + I+D + Sbjct: 253 PLPAKCIQVTEVKSSTLNPVWKEHFLFEIEDVSTDQLHLDIWDHD 297
>RSP5_YEAST (P39940) E3 ubiquitin--protein ligase RSP5 (EC 6.3.2.-)| Length = 809 Score = 38.9 bits (89), Expect = 0.011 Identities = 23/81 (28%), Positives = 41/81 (50%), Gaps = 2/81 (2%) Frame = +2 Query: 20 RXLVGKSDPFAVLYIRPLSAKTKKSKTINNDLNPIWNEHYEFVVEDSSTQHLTVKIYDDE 199 R + DPFAVL I +TK + LNP WNE ++F + + LT++++D + Sbjct: 18 RDVFRSPDPFAVLTID--GYQTKSTSAAKKTLNPYWNETFKF-DDINENSILTIQVFDQK 74 Query: 200 GLQPSE--IIGCARVDLSDIM 256 + + +G V + D++ Sbjct: 75 KFKKKDQGFLGVVNVRVGDVL 95
>UN13C_MOUSE (Q8K0T7) Unc-13 homolog C (Munc13-3) (Fragment)| Length = 1430 Score = 38.9 bits (89), Expect = 0.011 Identities = 17/56 (30%), Positives = 34/56 (60%) Frame = +2 Query: 32 GKSDPFAVLYIRPLSAKTKKSKTINNDLNPIWNEHYEFVVEDSSTQHLTVKIYDDE 199 G SDP+ + + +++KTI +LNP+W+E + F +ST + V+++D++ Sbjct: 1235 GSSDPYVTVQV---GKNKRRTKTIFGNLNPVWDEKFFFECH-NSTDRIKVRVWDED 1286 Score = 32.0 bits (71), Expect = 1.4 Identities = 12/36 (33%), Positives = 24/36 (66%) Frame = +2 Query: 494 LSVTVISAEDIPAMDVMGKADPFVVLYLKKGETKKK 601 +++TV+SA+ + A D G +DP+V + + K + + K Sbjct: 1218 ITITVVSAQGLQAKDKTGSSDPYVTVQVGKNKRRTK 1253
>KPC1_DROME (P05130) Protein kinase C, brain isozyme (EC 2.7.11.13) (PKC)| (dPKC53E(BR)) Length = 679 Score = 38.9 bits (89), Expect = 0.011 Identities = 24/91 (26%), Positives = 46/91 (50%), Gaps = 4/91 (4%) Frame = +2 Query: 32 GKSDPFAVLYIRP--LSAKTKKSKTINNDLNPIWNE--HYEFVVEDSSTQHLTVKIYDDE 199 G SDP+ + + P KK++TI LNP+WNE Y+ ED + + ++++D + Sbjct: 208 GLSDPYVKVKLIPDDKDQSKKKTRTIKACLNPVWNETLTYDLKPEDKD-RRILIEVWDWD 266 Query: 200 GLQPSEIIGCARVDLSDIMPGKVKDVWLELV 292 ++ +G +S+I+ W +L+ Sbjct: 267 RTSRNDFMGALSFGISEIIKNPTNG-WFKLL 296
>PUB1_SCHPO (Q92462) E3 ubiquitin--protein ligase pub1 (EC 6.3.2.-)| Length = 767 Score = 38.5 bits (88), Expect = 0.015 Identities = 20/53 (37%), Positives = 31/53 (58%) Frame = +2 Query: 41 DPFAVLYIRPLSAKTKKSKTINNDLNPIWNEHYEFVVEDSSTQHLTVKIYDDE 199 DPFAVL + +T + I LNP WNE +E V D+ST + ++++D + Sbjct: 30 DPFAVLTVD--GEQTHTTTAIKKTLNPYWNETFEVNVTDNST--IAIQVFDQK 78
>BAIP3_MOUSE (Q80TT2) BAI1-associated protein 3 (BAP3)| Length = 1134 Score = 38.5 bits (88), Expect = 0.015 Identities = 17/45 (37%), Positives = 29/45 (64%), Gaps = 1/45 (2%) Frame = +2 Query: 68 PLSAKT-KKSKTINNDLNPIWNEHYEFVVEDSSTQHLTVKIYDDE 199 PL AK + ++ N+ LNP+W EH+ F ++D +T L + I+D + Sbjct: 216 PLPAKCIQVTEVKNSTLNPVWKEHFLFEIDDVNTDQLHLDIWDHD 260
>RASA2_MOUSE (P58069) Ras GTPase-activating protein 2 (GAP1m)| Length = 848 Score = 38.5 bits (88), Expect = 0.015 Identities = 23/87 (26%), Positives = 43/87 (49%) Frame = +2 Query: 89 KSKTINNDLNPIWNEHYEFVVEDSSTQHLTVKIYDDEGLQPSEIIGCARVDLSDIMPGKV 268 +++ + L+P ++E + F + + Q+L+ +YD LQ IG + D+ Sbjct: 75 RTQVVEKSLSPYFSEEFYFEIP-RTFQYLSFYVYDKNVLQRDLRIGKVAIKKEDLCSHSG 133 Query: 269 KDVWLELVKDLEIQRDKKPRGQVHLEL 349 K+ W L I + + +G+VHLEL Sbjct: 134 KETWFSL---QPIDSNSEVQGKVHLEL 157
>RASA2_RAT (Q63713) Ras GTPase-activating protein 2 (GAP1m)| Length = 847 Score = 38.5 bits (88), Expect = 0.015 Identities = 23/87 (26%), Positives = 43/87 (49%) Frame = +2 Query: 89 KSKTINNDLNPIWNEHYEFVVEDSSTQHLTVKIYDDEGLQPSEIIGCARVDLSDIMPGKV 268 +++ + L+P ++E + F + + Q+L+ +YD LQ IG + D+ Sbjct: 74 RTQVVEKSLSPYFSEEFYFEIP-RTFQYLSFYVYDKNVLQRDLRIGKVAIKKEDLCSHSG 132 Query: 269 KDVWLELVKDLEIQRDKKPRGQVHLEL 349 K+ W L I + + +G+VHLEL Sbjct: 133 KETWFSL---QPIDSNSEVQGKVHLEL 156
>PP16A_CUCMA (Q9ZT47) 16 kDa phloem protein 1| Length = 149 Score = 38.5 bits (88), Expect = 0.015 Identities = 19/80 (23%), Positives = 41/80 (51%), Gaps = 3/80 (3%) Frame = +2 Query: 41 DPFAVLYIRPLSAKTKKSKTINNDLNPIWNEHYEFVVE---DSSTQHLTVKIYDDEGLQP 211 DP+A + + +K +K N NP+W+E ++F+ E H+ K+ D + + Sbjct: 26 DPYAEINFKGQERMSKVAK--NAGPNPLWDEKFKFLAEYPGSGGDFHILFKVMDHDAIDG 83 Query: 212 SEIIGCARVDLSDIMPGKVK 271 + IG ++D+ +++ V+ Sbjct: 84 DDYIGDVKIDVKNLLAEGVR 103
>RASA2_HUMAN (Q15283) Ras GTPase-activating protein 2 (GAP1m)| Length = 849 Score = 38.1 bits (87), Expect = 0.020 Identities = 22/87 (25%), Positives = 43/87 (49%) Frame = +2 Query: 89 KSKTINNDLNPIWNEHYEFVVEDSSTQHLTVKIYDDEGLQPSEIIGCARVDLSDIMPGKV 268 +++ + L+P ++E + F + + Q+L+ +YD LQ IG + D+ Sbjct: 75 RTQVVEKSLSPFFSEEFYFEIP-RTFQYLSFYVYDKNVLQRDLRIGKVAIKKEDLCNHSG 133 Query: 269 KDVWLELVKDLEIQRDKKPRGQVHLEL 349 K+ W L + + + +G+VHLEL Sbjct: 134 KETWFSL---QPVDSNSEVQGKVHLEL 157
>PCLO_CHICK (Q9PU36) Protein piccolo (Aczonin) (Fragment)| Length = 5120 Score = 38.1 bits (87), Expect = 0.020 Identities = 31/116 (26%), Positives = 49/116 (42%), Gaps = 15/116 (12%) Frame = +2 Query: 32 GKSDPFAVLYIRP----------LSAKTKK-SKTINNDLNPIWNE---HYEFVVEDSSTQ 169 G SDPF +Y+ P SA+ K+ +K + LNP WN+ + E + Sbjct: 4645 GYSDPFVKVYLLPGRGQVMVVQNASAEYKRRTKYVQKSLNPEWNQTVIYKNISTEQLKKK 4704 Query: 170 HLTVKIYDDEGLQPSEIIGCARVDLSDIMPGKVKDVWLELVKDLE-IQRDKKPRGQ 334 L V ++D + ++ +G +DLS + W L + E I K GQ Sbjct: 4705 TLEVTVWDYDRFSSNDFLGEVLIDLSSVSQLDNTPRWYPLKEQSENIDHGKSHSGQ 4760
>SMUF1_XENLA (Q9PUN2) Smad ubiquitination regulatory factor 1 (EC 6.3.2.-)| (Ubiquitin--protein ligase SMURF1) (Smad-specific E3 ubiquitin ligase) (xSMURF1) Length = 731 Score = 38.1 bits (87), Expect = 0.020 Identities = 32/109 (29%), Positives = 57/109 (52%), Gaps = 6/109 (5%) Frame = +2 Query: 41 DPFAVLYIRPLSAKTKKSKTINNDLNPIWNEHYEFVVEDSSTQHLTVKIYDDEGL---QP 211 DPFA + + S + + T+ N L+P WN+HY+ V +T+ I++ + + Q Sbjct: 35 DPFAKIVVDG-SGQCHSTDTVKNTLDPKWNQHYDLYV--GKMDSITISIWNHKKIHKKQG 91 Query: 212 SEIIGCARVDLSDIMPGKVKDVW---LELVKDLEIQRDKKPRGQVHLEL 349 + +GC R+ LS+ + ++KD L+L K L + RGQ+ + L Sbjct: 92 AGFLGCVRL-LSNAI-SRLKDTGYQRLDLCK-LNPTDNDAVRGQIVVSL 137
>PCLO_HUMAN (Q9Y6V0) Protein piccolo (Aczonin)| Length = 5183 Score = 37.7 bits (86), Expect = 0.026 Identities = 22/77 (28%), Positives = 37/77 (48%), Gaps = 5/77 (6%) Frame = +2 Query: 32 GKSDPFAVLYIRPLSAKTKKSKT--INNDLNPIWNE---HYEFVVEDSSTQHLTVKIYDD 196 G SDPF +Y+ P K +T + LNP WN+ + +E + L V ++D Sbjct: 4597 GYSDPFVKVYLLPGRGAEYKRRTKHVQKSLNPEWNQTVIYKSISMEQLKKKTLEVTVWDY 4656 Query: 197 EGLQPSEIIGCARVDLS 247 + ++ +G +DLS Sbjct: 4657 DRFSSNDFLGEVLIDLS 4673
>PIPA_DICDI (Q02158) 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase| (EC 3.1.4.11) (PLC) (Phosphoinositide phospholipase C) Length = 801 Score = 37.7 bits (86), Expect = 0.026 Identities = 25/77 (32%), Positives = 38/77 (49%), Gaps = 3/77 (3%) Frame = +2 Query: 41 DPFAVLYI--RPLSAKTKKSKTI-NNDLNPIWNEHYEFVVEDSSTQHLTVKIYDDEGLQP 211 DP+ L I K +K+K I NN NP W E +EF + +S L +++ DD+ Sbjct: 699 DPYVTLSIVGTHFDQKVEKTKVIDNNGFNPHWGEEFEFPLYNSQLSMLLIRV-DDKDKVG 757 Query: 212 SEIIGCARVDLSDIMPG 262 IG + + +I PG Sbjct: 758 HNRIGHHCIRVENIRPG 774
>PLDA1_PIMBR (O04883) Phospholipase D alpha 1 (EC 3.1.4.4) (PLD alpha 1)| (Choline phosphatase 1) (Phosphatidylcholine-hydrolyzing phospholipase D 1) Length = 808 Score = 37.7 bits (86), Expect = 0.026 Identities = 31/120 (25%), Positives = 57/120 (47%), Gaps = 5/120 (4%) Frame = +2 Query: 14 RTRXLVGKSDPFAVLYIRPLSAKTKKSKTINNDLN-PIWNEHYEFVVEDSSTQHL-TVKI 187 R ++ K P I A+ +++ I N+ N P WNE + ST + TVK Sbjct: 37 RKPLVLAKGTPKIYASIDLDKARVGRTRMIENEPNNPKWNESFHIYCGHPSTNVIFTVK- 95 Query: 188 YDDEGLQPSEIIGCARVDLSDIMPGKVKDVWLELVKDLEIQRDKKP---RGQVHLELLYY 358 D+ + +IG A + + +++ G+ D W+E+ + DK P ++H++L Y+ Sbjct: 96 --DDNPIGATLIGRAYLPVHELLEGEEVDKWVEI-----LDEDKNPISEGSKIHVKLQYF 148
>KPC2_CAEEL (P90980) Protein kinase C-like 2 (EC 2.7.11.13) (PKC2)| Length = 682 Score = 37.7 bits (86), Expect = 0.026 Identities = 20/79 (25%), Positives = 42/79 (53%), Gaps = 4/79 (5%) Frame = +2 Query: 32 GKSDPFAVLYIRPLSAKTK---KSKTINNDLNPIWNEHYEF-VVEDSSTQHLTVKIYDDE 199 G SDP+ + P + K K+KT+ LNP WNE + + ++ + L+++++D + Sbjct: 192 GLSDPYVKCKLIPEDSGCKSKQKTKTLRATLNPQWNETFTYKLLPGDKDRRLSIEVWDWD 251 Query: 200 GLQPSEIIGCARVDLSDIM 256 ++ +G +S++M Sbjct: 252 RTSRNDFMGSLSFGISELM 270
>SMUF2_HUMAN (Q9HAU4) Smad ubiquitination regulatory factor 2 (EC 6.3.2.-)| (Ubiquitin--protein ligase SMURF2) (Smad-specific E3 ubiquitin ligase 2) (hSMURF2) Length = 748 Score = 37.7 bits (86), Expect = 0.026 Identities = 19/69 (27%), Positives = 39/69 (56%), Gaps = 3/69 (4%) Frame = +2 Query: 41 DPFAVLYIRPLSAKTKKSKTINNDLNPIWNEHYEFVVEDSSTQHLTVKIYDDEGL---QP 211 DPFA + + S + + T+ N L+P WN+HY+ + S + +T+ +++ + + Q Sbjct: 34 DPFAKVVVDG-SGQCHSTDTVKNTLDPKWNQHYDLYIGKSDS--VTISVWNHKKIHKKQG 90 Query: 212 SEIIGCARV 238 + +GC R+ Sbjct: 91 AGFLGCVRL 99
>PLDA1_MAIZE (Q43270) Phospholipase D alpha 1 (EC 3.1.4.4) (PLD alpha 1)| (Choline phosphatase 1) (Phosphatidylcholine-hydrolyzing phospholipase D 1) Length = 812 Score = 37.4 bits (85), Expect = 0.033 Identities = 26/100 (26%), Positives = 52/100 (52%), Gaps = 2/100 (2%) Frame = +2 Query: 77 AKTKKSKTINND-LNPIWNEHYEFVVEDSSTQHL-TVKIYDDEGLQPSEIIGCARVDLSD 250 A+ +++ I+N+ +NP W E + + + TVKI + G + +IG A + + D Sbjct: 63 ARVGRTRMISNEPVNPRWYESFHIYCAHMAADVIFTVKIDNSIG---ASLIGRAYLAVQD 119 Query: 251 IMPGKVKDVWLELVKDLEIQRDKKPRGQVHLELLYYPFDK 370 ++ G+ D WLE+ + R+ ++H++L Y+ K Sbjct: 120 LLGGEEIDKWLEISDE---NREPVGDSKIHVKLQYFDVGK 156
>OTOF_MOUSE (Q9ESF1) Otoferlin (Fer-1-like protein 2)| Length = 1997 Score = 37.4 bits (85), Expect = 0.033 Identities = 18/73 (24%), Positives = 39/73 (53%) Frame = +2 Query: 32 GKSDPFAVLYIRPLSAKTKKSKTINNDLNPIWNEHYEFVVEDSSTQHLTVKIYDDEGLQP 211 GK+DP+ + + + K++ I+ LNP++ + ++ LTV +YD + + Sbjct: 1511 GKADPYIAIKLGKTDIRDKENY-ISKQLNPVFGKSFDIEASFPMESMLTVAVYDWDLVGT 1569 Query: 212 SEIIGCARVDLSD 250 ++IG ++DL + Sbjct: 1570 DDLIGETKIDLEN 1582 Score = 32.3 bits (72), Expect = 1.1 Identities = 17/51 (33%), Positives = 27/51 (52%) Frame = +2 Query: 449 GYDVNQRKNVITRGVLSVTVISAEDIPAMDVMGKADPFVVLYLKKGETKKK 601 G N NV+ R + V+ A D+ D+ GKADP++ + L K + + K Sbjct: 1483 GIPSNDPINVLVR----IYVVRATDLHPADINGKADPYIAIKLGKTDIRDK 1529
>OTOF_HUMAN (Q9HC10) Otoferlin (Fer-1-like protein 2)| Length = 1997 Score = 37.4 bits (85), Expect = 0.033 Identities = 18/73 (24%), Positives = 39/73 (53%) Frame = +2 Query: 32 GKSDPFAVLYIRPLSAKTKKSKTINNDLNPIWNEHYEFVVEDSSTQHLTVKIYDDEGLQP 211 GK+DP+ + + + K++ I+ LNP++ + ++ LTV +YD + + Sbjct: 1511 GKADPYIAIRLGKTDIRDKENY-ISKQLNPVFGKSFDIEASFPMESMLTVAVYDWDLVGT 1569 Query: 212 SEIIGCARVDLSD 250 ++IG ++DL + Sbjct: 1570 DDLIGETKIDLEN 1582 Score = 32.7 bits (73), Expect = 0.82 Identities = 18/51 (35%), Positives = 27/51 (52%) Frame = +2 Query: 449 GYDVNQRKNVITRGVLSVTVISAEDIPAMDVMGKADPFVVLYLKKGETKKK 601 G N NV+ R V V+ A D+ D+ GKADP++ + L K + + K Sbjct: 1483 GIPSNDPINVLVR----VYVVRATDLHPADINGKADPYIAIRLGKTDIRDK 1529
>SYT4_RAT (P50232) Synaptotagmin-4 (Synaptotagmin IV) (SytIV)| Length = 425 Score = 37.4 bits (85), Expect = 0.033 Identities = 45/199 (22%), Positives = 80/199 (40%), Gaps = 11/199 (5%) Frame = +2 Query: 38 SDPFAVLYIRPLSAKTKKSKTINNDLNPIWNEHYEFV------VEDSSTQHLTVKIYDDE 199 SDP+ + I P K++ + L+P+++E + F +++ S H TV +D Sbjct: 190 SDPYIKMTILPEKKHKVKTRVLRKTLDPVFDETFTFYGVPYPHIQELSL-HFTVLSFD-- 246 Query: 200 GLQPSEIIGCARVDLSDIMPGKVKDVWLELVKDLEIQRDKKP--RGQVHLELLYYPFDKQ 373 ++IG V LS I ++ D + + +++ + KK RG++ + L Y Sbjct: 247 RFSRDDVIGEVLVPLSGI---ELSDGKMLMTREIIKRNAKKSSGRGELLVSLCYQS---- 299 Query: 374 EGVSNPFASQIQLTSLEKVLKTESNGYDVNQRKNVITRGVLSVTVISAEDIPAMDVMGKA 553 T L+V V+ A +P DV G + Sbjct: 300 ------------------------------------TTNTLTVVVLKARHLPKSDVSGLS 323 Query: 554 DPFV---VLYLKKGETKKK 601 DP+V + + KK +KKK Sbjct: 324 DPYVKVNLYHAKKRISKKK 342
>NEDD4_HUMAN (P46934) E3 ubiquitin-protein ligase NEDD4 (EC 6.3.2.-)| Length = 1000 Score = 37.4 bits (85), Expect = 0.033 Identities = 36/136 (26%), Positives = 59/136 (43%), Gaps = 6/136 (4%) Frame = +2 Query: 20 RXLVGKSDPFA-VLYIRPLSA--KTKKSKTINNDLNPIWNEHYEFVVEDSSTQHLTVKIY 190 + ++G SDP+ V P++ + ++KTI LNP WNE F V L +++ Sbjct: 134 KDILGASDPYVRVTLYDPMNGVLTSVQTKTIKKSLNPKWNEEILFRVHPQQ-HRLLFEVF 192 Query: 191 DDEGLQPSEIIGCARVDLSDIMPGKVKDVWLELVKDLEIQ-RDKKPR--GQVHLELLYYP 361 D+ L + +G V L + + KD + R K R G + L++ Y P Sbjct: 193 DENRLTRDDFLGQVDVPLYPLPTENPRLERPYTFKDFVLHPRSHKSRVKGYLRLKMTYLP 252 Query: 362 FDKQEGVSNPFASQIQ 409 K G + A Q + Sbjct: 253 --KTSGSEDDNAEQAE 266
>PLDB1_ARATH (P93733) Phospholipase D beta 1 (EC 3.1.4.4) (AtPLDbeta1) (PLD beta| 1) (PLDbeta) Length = 967 Score = 37.4 bits (85), Expect = 0.033 Identities = 29/113 (25%), Positives = 52/113 (46%), Gaps = 2/113 (1%) Frame = +2 Query: 38 SDPFAVLYIRPLSAKTKKSKTINNDLNPIWNEH-YEFVVEDSSTQHLTVKIYDDEGLQPS 214 SDP+ + + A ++ ++N NP+W +H Y V ++ H VK D + S Sbjct: 199 SDPYVSVSVA--GAVIGRTYVMSNSENPVWMQHFYVPVAHHAAEVHFVVK---DSDVVGS 253 Query: 215 EIIGCARVDLSDIMPG-KVKDVWLELVKDLEIQRDKKPRGQVHLELLYYPFDK 370 ++IG + + I G K++ + L + + KP + L + Y P DK Sbjct: 254 QLIGLVTIPVEQIYSGAKIEGTYPILTSN---GKPCKPGANLSLSIQYTPMDK 303
>SYT4_MOUSE (P40749) Synaptotagmin-4 (Synaptotagmin IV) (SytIV)| Length = 425 Score = 37.0 bits (84), Expect = 0.044 Identities = 44/199 (22%), Positives = 80/199 (40%), Gaps = 11/199 (5%) Frame = +2 Query: 38 SDPFAVLYIRPLSAKTKKSKTINNDLNPIWNEHYEFV------VEDSSTQHLTVKIYDDE 199 SDP+ + I P K++ + L+P+++E + F +++ S H TV +D Sbjct: 190 SDPYIKMTILPEKKHRVKTRVLRKTLDPVFDETFTFYGIPYPHIQELSL-HFTVLSFD-- 246 Query: 200 GLQPSEIIGCARVDLSDIMPGKVKDVWLELVKDLEIQRDKKP--RGQVHLELLYYPFDKQ 373 ++IG + LS I ++ D + + +++ + KK RG++ + L Y Sbjct: 247 RFSRDDVIGEVLIPLSGI---ELSDGKMLMTREIIKRNAKKSSGRGELLVSLCYQS---- 299 Query: 374 EGVSNPFASQIQLTSLEKVLKTESNGYDVNQRKNVITRGVLSVTVISAEDIPAMDVMGKA 553 T L+V V+ A +P DV G + Sbjct: 300 ------------------------------------TTNTLTVVVLKARHLPKSDVSGLS 323 Query: 554 DPFV---VLYLKKGETKKK 601 DP+V + + KK +KKK Sbjct: 324 DPYVKVNLYHAKKRISKKK 342
>NEDD4_MOUSE (P46935) E3 ubiquitin-protein ligase NEDD4 (EC 6.3.2.-) (Neural| precursor cell expressed developmentally down-regulated protein 4) Length = 887 Score = 37.0 bits (84), Expect = 0.044 Identities = 34/136 (25%), Positives = 60/136 (44%), Gaps = 6/136 (4%) Frame = +2 Query: 20 RXLVGKSDPFA-VLYIRPLSA--KTKKSKTINNDLNPIWNEHYEFVVEDSSTQHLTVKIY 190 + ++G SDP+ V P+S + ++KTI LNP WNE F V + +++ Sbjct: 93 KDILGASDPYVRVTLYDPMSGILTSVQTKTIKKSLNPKWNEEILFRVL-PQRHRILFEVF 151 Query: 191 DDEGLQPSEIIGCARVDLSDIMPGKVKDVWLELVKDLEIQ-RDKKPR--GQVHLELLYYP 361 D+ L + +G V L + + KD + R K R G + L++ Y P Sbjct: 152 DENRLTRDDFLGQVDVPLYPLPTENPRMERPYTFKDFVLHPRSHKSRVKGYLRLKMTYLP 211 Query: 362 FDKQEGVSNPFASQIQ 409 + E + A +++ Sbjct: 212 KNGSEDENADQAEELE 227
>YKH3_SCHPO (Q9UT00) Hypothetical protein PYUK71.03c in chromosome I| Length = 1225 Score = 37.0 bits (84), Expect = 0.044 Identities = 18/34 (52%), Positives = 23/34 (67%) Frame = +2 Query: 488 GVLSVTVISAEDIPAMDVMGKADPFVVLYLKKGE 589 G ++V VI A D+PA D GK+DPFVV L+ E Sbjct: 1037 GEMTVDVIKATDLPAADSNGKSDPFVVFELQGEE 1070 Score = 35.4 bits (80), Expect = 0.13 Identities = 26/96 (27%), Positives = 52/96 (54%), Gaps = 2/96 (2%) Frame = +2 Query: 8 EGRTRXLVGKSDPFAVLYIRPLSAKTKKSKTINNDLNPIWNEHYEFVVEDSSTQHLTVKI 187 +G L G DP+ V+ KSK +N +P++NE + + V +S +++L +++ Sbjct: 445 DGFKDGLGGAVDPYVVIK-NSADRVIGKSKVAHNTGSPVFNETF-YSVLNSFSENLNLEV 502 Query: 188 YDDEGLQPSEIIGCARVDLS--DIMPGKVKDVWLEL 289 YD ++ +++G A + L+ + MP D ++EL Sbjct: 503 YDFNDIRSDKLLGSAVLPLATLEAMP-VTNDAFVEL 537 Score = 35.0 bits (79), Expect = 0.17 Identities = 19/70 (27%), Positives = 34/70 (48%) Frame = +2 Query: 32 GKSDPFAVLYIRPLSAKTKKSKTINNDLNPIWNEHYEFVVEDSSTQHLTVKIYDDEGLQP 211 GKSDPF V ++ + ++KT LNP +NE +E + T + ++D + Sbjct: 1056 GKSDPFVVFELQ--GEEVYRTKTHKRTLNPTFNESFEVELPCKQTCNFVANVFDWDFGNK 1113 Query: 212 SEIIGCARVD 241 + +G +D Sbjct: 1114 DDHLGSCVID 1123
>SYT11_RAT (O08835) Synaptotagmin-11 (Synaptotagmin XI) (SytXI)| Length = 430 Score = 36.2 bits (82), Expect = 0.074 Identities = 45/197 (22%), Positives = 80/197 (40%), Gaps = 9/197 (4%) Frame = +2 Query: 38 SDPFAVLYIRPLSAKTKKSKTINNDLNPIWNEHYEFV-VEDSSTQHLTVK--IYDDEGLQ 208 SDP+ + I P K++ + L+P+++E + F + S Q L + + + Sbjct: 193 SDPYIKMTILPDKRHRVKTRVLRKTLDPVFDETFTFYGIPYSQLQDLVLHFLVLSFDRFS 252 Query: 209 PSEIIGCARVDLSDIMPGKVKDVWLELVKDLEIQRDKK--PRGQVHLELLYYPFDKQEGV 382 ++IG V L+ + P K ++L +D+ + +K RG++ + L Y P Sbjct: 253 RDDVIGEVMVPLAGVDPSTGK---VQLTRDIIKRNIQKCISRGELQVSLSYQP------- 302 Query: 383 SNPFASQIQLTSLEKVLKTESNGYDVNQRKNVITRGVLSVTVISAEDIPAMDVMG-KADP 559 V QR ++V V+ A +P MD+ G +P Sbjct: 303 -------------------------VAQR--------MTVVVLKARHLPKMDITGLSGNP 329 Query: 560 FV---VLYLKKGETKKK 601 +V V Y +K KKK Sbjct: 330 YVKVNVYYGRKRIAKKK 346
>SYT11_MOUSE (Q9R0N3) Synaptotagmin-11 (Synaptotagmin XI) (SytXI)| Length = 430 Score = 36.2 bits (82), Expect = 0.074 Identities = 45/197 (22%), Positives = 80/197 (40%), Gaps = 9/197 (4%) Frame = +2 Query: 38 SDPFAVLYIRPLSAKTKKSKTINNDLNPIWNEHYEFV-VEDSSTQHLTVK--IYDDEGLQ 208 SDP+ + I P K++ + L+P+++E + F + S Q L + + + Sbjct: 193 SDPYIKMTILPDKRHRVKTRVLRKTLDPVFDETFTFYGIPYSQLQDLVLHFLVLSFDRFS 252 Query: 209 PSEIIGCARVDLSDIMPGKVKDVWLELVKDLEIQRDKK--PRGQVHLELLYYPFDKQEGV 382 ++IG V L+ + P K ++L +D+ + +K RG++ + L Y P Sbjct: 253 RDDVIGEVMVPLAGVDPSTGK---VQLTRDIIKRNIQKCISRGELQVSLSYQP------- 302 Query: 383 SNPFASQIQLTSLEKVLKTESNGYDVNQRKNVITRGVLSVTVISAEDIPAMDVMG-KADP 559 V QR ++V V+ A +P MD+ G +P Sbjct: 303 -------------------------VAQR--------MTVVVLKARHLPKMDITGLSGNP 329 Query: 560 FV---VLYLKKGETKKK 601 +V V Y +K KKK Sbjct: 330 YVKVNVYYGRKRIAKKK 346
>NEDD4_DROME (Q9VVI3) E3 ubiquitin-protein ligase Nedd-4 (EC 6.3.2.-) (DNedd4)| Length = 1007 Score = 36.2 bits (82), Expect = 0.074 Identities = 20/82 (24%), Positives = 39/82 (47%), Gaps = 4/82 (4%) Frame = +2 Query: 20 RXLVGKSDPFAVLYIRPLSAKTK----KSKTINNDLNPIWNEHYEFVVEDSSTQHLTVKI 187 + + G SDP+ + + ++ +KT LNP WNE + F V+ S L ++ Sbjct: 85 KDIFGASDPYVRIDLNTINGDINIDSVLTKTKKKTLNPTWNEEFIFRVKPSE-HKLVFQV 143 Query: 188 YDDEGLQPSEIIGCARVDLSDI 253 +D+ L + +G + L ++ Sbjct: 144 FDENRLTRDDFLGMVELTLVNL 165
>SYT11_HUMAN (Q9BT88) Synaptotagmin-11 (Synaptotagmin XI) (SytXI)| Length = 431 Score = 36.2 bits (82), Expect = 0.074 Identities = 45/197 (22%), Positives = 80/197 (40%), Gaps = 9/197 (4%) Frame = +2 Query: 38 SDPFAVLYIRPLSAKTKKSKTINNDLNPIWNEHYEFV-VEDSSTQHLTVK--IYDDEGLQ 208 SDP+ + I P K++ + L+P+++E + F + S Q L + + + Sbjct: 194 SDPYIKMTILPDKRHRVKTRVLRKTLDPVFDETFTFYGIPYSQLQDLVLHFLVLSFDRFS 253 Query: 209 PSEIIGCARVDLSDIMPGKVKDVWLELVKDLEIQRDKK--PRGQVHLELLYYPFDKQEGV 382 ++IG V L+ + P K ++L +D+ + +K RG++ + L Y P Sbjct: 254 RDDVIGEVMVPLAGVDPSTGK---VQLTRDIIKRNIQKCISRGELQVSLSYQP------- 303 Query: 383 SNPFASQIQLTSLEKVLKTESNGYDVNQRKNVITRGVLSVTVISAEDIPAMDVMG-KADP 559 V QR ++V V+ A +P MD+ G +P Sbjct: 304 -------------------------VAQR--------MTVVVLKARHLPKMDITGLSGNP 330 Query: 560 FV---VLYLKKGETKKK 601 +V V Y +K KKK Sbjct: 331 YVKVNVYYGRKRIAKKK 347
>NEDD4_RAT (Q62940) E3 ubiquitin-protein ligase NEDD4 (EC 6.3.2.-)| Length = 887 Score = 36.2 bits (82), Expect = 0.074 Identities = 32/120 (26%), Positives = 53/120 (44%), Gaps = 6/120 (5%) Frame = +2 Query: 20 RXLVGKSDPFA-VLYIRPLSA--KTKKSKTINNDLNPIWNEHYEFVVEDSSTQHLTVKIY 190 + ++G SDP+ V P+S + ++KTI LNP WNE F V + +++ Sbjct: 90 KDILGASDPYVRVTLYDPMSGVLTSVQTKTIKKSLNPKWNEEILFRVLPQQ-HRILFEVF 148 Query: 191 DDEGLQPSEIIGCARVDLSDIMPGKVKDVWLELVKDLEIQ-RDKKPR--GQVHLELLYYP 361 D+ L + +G V L + + KD + R K R G + L++ Y P Sbjct: 149 DENRLTRDDFLGQVDVPLYPLPTENPRMERPYTFKDFVLHPRSHKSRVKGYLRLKMTYLP 208
>PLDG3_ARATH (Q9T052) Phospholipase D gamma 3 (EC 3.1.4.4) (AtPLDgamma3) (PLD| gamma 3) Length = 866 Score = 35.8 bits (81), Expect = 0.097 Identities = 22/76 (28%), Positives = 37/76 (48%), Gaps = 1/76 (1%) Frame = +2 Query: 38 SDPFAVLYIRPLSAKTKKSKTINNDLNPIWNEHYEFVVEDSSTQ-HLTVKIYDDEGLQPS 214 SDP+ + I A ++ I+N NP+W +H++ V S+ + H VK D + S Sbjct: 93 SDPYVTVSIS--GAVIGRTFVISNSENPVWMQHFDVPVAHSAAKVHFVVK---DSDIIGS 147 Query: 215 EIIGCARVDLSDIMPG 262 +IIG + + G Sbjct: 148 QIIGAVEIPTEQLCSG 163
>RPGR1_HUMAN (Q96KN7) X-linked retinitis pigmentosa GTPase regulator-interacting| protein 1 (RPGR-interacting protein 1) Length = 1286 Score = 35.8 bits (81), Expect = 0.097 Identities = 38/143 (26%), Positives = 61/143 (42%), Gaps = 15/143 (10%) Frame = +2 Query: 14 RTRXLVGKSDPFAVLYIRPLSAKTKKSKTINNDLNPIWNEHYEF-VVEDSSTQH------ 172 R+R L + P+AV R + + I NP + + F V+ S H Sbjct: 812 RSRWLGTQPSPYAVY--RFFTFSDHDTAIIPASNNPYFRDQARFPVLVTSDLDHYLRREA 869 Query: 173 LTVKIYDDEGLQPSEIIGCARVDLSDIMPGKVKDVWLELVKDLEIQRD-------KKPRG 331 L++ ++DDE L+P +G ARV L L L K+ I+ D +KP G Sbjct: 870 LSIHVFDDEDLEPGSYLGRARVPL------------LPLAKNESIKGDFNLTDPAEKPNG 917 Query: 332 QVHLELLY-YPFDKQEGVSNPFA 397 + ++L + +P+ E P A Sbjct: 918 SIQVQLDWKFPYIPPESFLKPEA 940
>PCLO_RAT (Q9JKS6) Protein piccolo (Aczonin) (Multidomain presynaptic| cytomatrix protein) Length = 5085 Score = 35.4 bits (80), Expect = 0.13 Identities = 24/86 (27%), Positives = 41/86 (47%), Gaps = 14/86 (16%) Frame = +2 Query: 32 GKSDPFAVLYIRP----------LSAKTKK-SKTINNDLNPIWNE---HYEFVVEDSSTQ 169 G SDPF +Y+ P SA+ K+ +K + LNP WN+ + +E + Sbjct: 4671 GYSDPFVKVYLLPGRGQVMVVQNASAEYKRRTKYVQKSLNPEWNQTVIYKSISMEQLMKK 4730 Query: 170 HLTVKIYDDEGLQPSEIIGCARVDLS 247 L V ++D + ++ +G +DLS Sbjct: 4731 TLEVTVWDYDRFSSNDFLGEVLIDLS 4756
>PLDA1_RICCO (Q41142) Phospholipase D alpha 1 precursor (EC 3.1.4.4) (PLD 1)| (Choline phosphatase 1) (Phosphatidylcholine-hydrolyzing phospholipase D 1) Length = 808 Score = 35.4 bits (80), Expect = 0.13 Identities = 25/93 (26%), Positives = 44/93 (47%), Gaps = 4/93 (4%) Frame = +2 Query: 104 NNDLNPIWNEHYE-FVVEDSSTQHLTVKIYDDEGLQPSEIIGCARVDLSDIMPGKVKDVW 280 N NP W E + + +S TVK D+ + +IG A V + +++ G+ D W Sbjct: 68 NEQSNPRWYESFHVYCAHQASNVIFTVK---DDNPIGATLIGRAYVPVEELLDGEEIDRW 124 Query: 281 LELVKDLEIQRDKKP---RGQVHLELLYYPFDK 370 +E+ + DK P ++H++L Y+ K Sbjct: 125 VEI-----LDEDKNPVHSGSKIHVKLQYFEVTK 152
>SYT13_RAT (Q925B5) Synaptotagmin-13 (Synaptotagmin XIII) (SytXIII)| Length = 426 Score = 35.4 bits (80), Expect = 0.13 Identities = 29/103 (28%), Positives = 49/103 (47%), Gaps = 5/103 (4%) Frame = +2 Query: 5 HEGRTRXLVGKSDPFAV-LYIRPLSAKTKKSKTINNDLNPIWNEHYEFVVEDSSTQHLTV 181 H +++ L+GK V L + K K++K + +NP+WNE F + D Q +V Sbjct: 315 HSNQSKELLGKDVSVKVTLKHQAQKLKKKQTKRAKHKINPVWNEMIMFELPDDLLQASSV 374 Query: 182 KI----YDDEGLQPSEIIGCARVDLSDIMPGKVKDVWLELVKD 298 ++ +EG PS +G R L G + W E++K+ Sbjct: 375 ELEVLGQGEEG--PSCELG--RCSLGLHASGSERSHWEEMLKN 413
>PLDG2_ARATH (Q9T051) Phospholipase D gamma 2 (EC 3.1.4.4) (AtPLDgamma2) (PLD| gamma 2) Length = 824 Score = 35.0 bits (79), Expect = 0.17 Identities = 23/76 (30%), Positives = 37/76 (48%), Gaps = 1/76 (1%) Frame = +2 Query: 38 SDPFAVLYIRPLSAKTKKSKTINNDLNPIWNEHYEFVVEDSSTQ-HLTVKIYDDEGLQPS 214 SDP+ + I A ++ I+N NP+W +H++ V S+ + H VK D G S Sbjct: 52 SDPYVTVSIS--GAVIGRTFVISNSENPVWMQHFDVPVAHSAAEVHFVVKDNDPIG---S 106 Query: 215 EIIGCARVDLSDIMPG 262 +IIG + + G Sbjct: 107 KIIGVVGIPTKQLCSG 122
>PLDA1_VIGUN (O04865) Phospholipase D alpha 1 (EC 3.1.4.4) (PLD alpha 1)| (Choline phosphatase 1) (Phosphatidylcholine-hydrolyzing phospholipase D 1) Length = 809 Score = 35.0 bits (79), Expect = 0.17 Identities = 26/99 (26%), Positives = 50/99 (50%), Gaps = 5/99 (5%) Frame = +2 Query: 77 AKTKKSKTINNDL-NPIWNEHYEFVVEDSSTQHL-TVKIYDDEGLQPSEIIGCARVDLSD 250 A+ +++ I N+ NP WNE + ++ + TVK D+ + +IG A V +S+ Sbjct: 58 ARVGRTRIIENETTNPKWNESFHIYCGHLASNIIFTVK---DDNPIGATLIGRAYVPVSE 114 Query: 251 IMPGKVKDVWLELVKDLEIQRDKKP---RGQVHLELLYY 358 ++ G D W+E+ + +K P ++H+ L Y+ Sbjct: 115 VLDGHEIDKWVEI-----LDTEKNPIEGGSKIHVRLQYF 148
>BRE1_DROME (Q9VRP9) Ubiquitin-protein ligase Bre1 (EC 6.3.2.-) (dBre1)| Length = 1044 Score = 35.0 bits (79), Expect = 0.17 Identities = 26/69 (37%), Positives = 37/69 (53%), Gaps = 1/69 (1%) Frame = +2 Query: 239 DLSDIMPGK-VKDVWLELVKDLEIQRDKKPRGQVHLELLYYPFDKQEGVSNPFASQIQLT 415 D D + GK VK V E V+DL+ Q K Q ++LL D +GVS ++QL Sbjct: 653 DSKDGVKGKDVKAVESETVRDLKAQLKKALNDQKEMKLL---LDMYKGVSKDQRDKVQLM 709 Query: 416 SLEKVLKTE 442 + EK L++E Sbjct: 710 ATEKKLRSE 718
>PCLO_MOUSE (Q9QYX7) Protein piccolo (Aczonin) (Multidomain presynaptic| cytomatrix protein) (Brain-derived HLMN protein) Length = 5038 Score = 34.7 bits (78), Expect = 0.22 Identities = 21/86 (24%), Positives = 39/86 (45%), Gaps = 14/86 (16%) Frame = +2 Query: 32 GKSDPFAVLYIRPLSAKT-----------KKSKTINNDLNPIWNE---HYEFVVEDSSTQ 169 G SDPF +Y+ P + +++K + LNP WN+ + +E + Sbjct: 4624 GYSDPFVKVYLLPGRGQVMVVQNASVEYKRRTKYVQKSLNPEWNQTVIYKSISMEQLMKK 4683 Query: 170 HLTVKIYDDEGLQPSEIIGCARVDLS 247 L V ++D + ++ +G +DLS Sbjct: 4684 TLEVTVWDYDRFSSNDFLGEVLIDLS 4709
>SYT13_HUMAN (Q7L8C5) Synaptotagmin-13 (Synaptotagmin XIII) (SytXIII)| Length = 426 Score = 34.7 bits (78), Expect = 0.22 Identities = 26/103 (25%), Positives = 45/103 (43%), Gaps = 5/103 (4%) Frame = +2 Query: 5 HEGRTRXLVGKSDPFAV-LYIRPLSAKTKKSKTINNDLNPIWNEHYEFVVEDSSTQHLTV 181 H +++ L+GK V L + K K++K + +NP+WNE F + D Q +V Sbjct: 315 HSNQSKELLGKDVSVKVTLKHQARKLKKKQTKRAKHKINPVWNEMIMFELPDDLLQASSV 374 Query: 182 KI----YDDEGLQPSEIIGCARVDLSDIMPGKVKDVWLELVKD 298 ++ DD G + L G + W E++K+ Sbjct: 375 ELEVLGQDDSG----QSCALGHCSLGLHTSGSERSHWEEMLKN 413
>KPC2_APLCA (Q16975) Calcium-independent protein kinase C (EC 2.7.11.13) (APL| II) Length = 743 Score = 34.3 bits (77), Expect = 0.28 Identities = 31/138 (22%), Positives = 58/138 (42%) Frame = +2 Query: 89 KSKTINNDLNPIWNEHYEFVVEDSSTQHLTVKIYDDEGLQPSEIIGCARVDLSDIMPGKV 268 K+ T + P W + +F E + Q++ + ++ D + P E + + D+ GK Sbjct: 60 KTTTKPKSVKPQWVWNEDFTSEVHNGQNVNLTVFHDAAIPPDEFVANCTIPFDDV-KGK- 117 Query: 269 KDVWLELVKDLEIQRDKKPRGQVHLELLYYPFDKQEGVSNPFASQIQLTSLEKVLKTESN 448 D W++L +P G++H+ + + + T EKV K E Sbjct: 118 SDFWIDL----------EPNGKLHVVI---------ELCGSATEAAESTPKEKVFK-EKE 157 Query: 449 GYDVNQRKNVITRGVLSV 502 G +N+R+ + R V V Sbjct: 158 GM-LNRRRGAMRRRVHQV 174
>SYT13_MOUSE (Q9EQT6) Synaptotagmin-13 (Synaptotagmin XIII) (SytXIII)| Length = 426 Score = 34.3 bits (77), Expect = 0.28 Identities = 29/103 (28%), Positives = 49/103 (47%), Gaps = 5/103 (4%) Frame = +2 Query: 5 HEGRTRXLVGKSDPFAV-LYIRPLSAKTKKSKTINNDLNPIWNEHYEFVVED----SSTQ 169 H +++ L+GK V L + K K++K + +NP+WNE F + D +S+ Sbjct: 315 HSNQSKELLGKDVSVKVTLKHQAQKLKKKQTKRAKHKINPVWNEMIMFELPDDLLRASSV 374 Query: 170 HLTVKIYDDEGLQPSEIIGCARVDLSDIMPGKVKDVWLELVKD 298 L V +EG PS +G + L G + W E++K+ Sbjct: 375 ELEVLGQGEEG--PSCELGHCSLGLH--ASGSERSHWEEMLKN 413
>PLDG1_ARATH (Q9T053) Phospholipase D gamma 1 (EC 3.1.4.4) (AtPLDgamma1) (PLD| gamma 1) (Choline phosphatase) (Lipophosphodiesterase II) (Lecithinase D) Length = 858 Score = 34.3 bits (77), Expect = 0.28 Identities = 21/76 (27%), Positives = 37/76 (48%), Gaps = 1/76 (1%) Frame = +2 Query: 38 SDPFAVLYIRPLSAKTKKSKTINNDLNPIWNEHYEFVVEDSSTQ-HLTVKIYDDEGLQPS 214 SDP+ + I A ++ I+N NP+W +H++ V S+ + H VK D + S Sbjct: 86 SDPYVTVSIS--GAVIGRTFVISNSENPVWMQHFDVPVAHSAAEVHFVVK---DSDIIGS 140 Query: 215 EIIGCARVDLSDIMPG 262 +I+G + + G Sbjct: 141 QIMGAVGIPTEQLCSG 156
>PLDB2_ARATH (O23078) Phospholipase D beta 2 (EC 3.1.4.4) (AtPLDbeta2) (PLD beta| 2) (PLDdelta1) Length = 915 Score = 33.9 bits (76), Expect = 0.37 Identities = 22/76 (28%), Positives = 36/76 (47%), Gaps = 1/76 (1%) Frame = +2 Query: 38 SDPFAVLYIRPLSAKTKKSKTINNDLNPIWNEH-YEFVVEDSSTQHLTVKIYDDEGLQPS 214 SDP+ + + A ++ I+N NP+W +H Y V ++ H VK D G S Sbjct: 160 SDPYVSISVA--GAVIGRTYVISNSENPVWQQHFYVPVAHHAAEVHFVVKDSDAVG---S 214 Query: 215 EIIGCARVDLSDIMPG 262 ++IG + + I G Sbjct: 215 QLIGIVTIPVEQIYSG 230
>PLDA1_ARATH (Q38882) Phospholipase D alpha 1 (EC 3.1.4.4) (AtPLDalpha1) (PLD| alpha 1) (Choline phosphatase 1) (Phosphatidylcholine-hydrolyzing phospholipase D 1) (PLDalpha) Length = 810 Score = 33.1 bits (74), Expect = 0.63 Identities = 28/115 (24%), Positives = 54/115 (46%), Gaps = 5/115 (4%) Frame = +2 Query: 29 VGKSDPFAVLYIRPLSAKTKKSKTINND-LNPIWNEHYE-FVVEDSSTQHLTVKIYDDEG 202 VGK + I A+ +++ I N+ NP W E + + +S TVK D+ Sbjct: 43 VGKGETQLYATIDLQKARVGRTRKIKNEPKNPKWYESFHIYCAHLASDIIFTVK---DDN 99 Query: 203 LQPSEIIGCARVDLSDIMPGKVKDVWLELVKDLEIQRDKKP---RGQVHLELLYY 358 + +IG A + + ++ G+ D W+E+ + D+ P ++H++L Y+ Sbjct: 100 PIGATLIGRAYIPVDQVINGEEVDQWVEI-----LDNDRNPIQGGSKIHVKLQYF 149
>PLDA1_TOBAC (P93400) Phospholipase D alpha 1 (EC 3.1.4.4) (PLD alpha 1)| (Choline phosphatase 1) (Phosphatidylcholine-hydrolyzing phospholipase D 1) Length = 808 Score = 32.7 bits (73), Expect = 0.82 Identities = 27/114 (23%), Positives = 54/114 (47%), Gaps = 5/114 (4%) Frame = +2 Query: 32 GKSDPFAVLYIRPLSAKTKKSKTINNDLN-PIWNEHYE-FVVEDSSTQHLTVKIYDDEGL 205 GK P + A+ +++ I N+ N P W E + + +S TVK D+ Sbjct: 43 GKGTPAIYATVDLEKARVGRTRKIKNEPNNPRWYESFHIYCAHMASNVIFTVK---DDNP 99 Query: 206 QPSEIIGCARVDLSDIMPGKVKDVWLELVKDLEIQRDKKP---RGQVHLELLYY 358 + +IG A V + +++ G+ D W+E+ + R+ P ++H++L ++ Sbjct: 100 IGATLIGRAYVPVEELLEGEEIDKWVEI-----LDREMNPIAEGSKIHVKLQFF 148
>ADR1_YEAST (P07248) Regulatory protein ADR1| Length = 1323 Score = 32.7 bits (73), Expect = 0.82 Identities = 22/85 (25%), Positives = 41/85 (48%), Gaps = 1/85 (1%) Frame = +2 Query: 347 LLYYPFDKQEGV-SNPFASQIQLTSLEKVLKTESNGYDVNQRKNVITRGVLSVTVISAED 523 ++YY +D ++G S+ F +I LE+ L T S G D N ++ T+I + Sbjct: 925 MIYYEYDLRKGTKSHVFLDRIDTKRLERSLDTSSYGNDNMAATNKNIAILIDDTIILKNN 984 Query: 524 IPAMDVMGKADPFVVLYLKKGETKK 598 + +M + + D ++KG+ K Sbjct: 985 LMSMRFIKQIDRSFTEKVRKGQIAK 1009
>CPNE2_MOUSE (P59108) Copine-2 (Copine II)| Length = 548 Score = 32.3 bits (72), Expect = 1.1 Identities = 27/111 (24%), Positives = 49/111 (44%), Gaps = 6/111 (5%) Frame = +2 Query: 20 RXLVGKSDPFAVLYIRPLS--AKTKKSKTINNDLNPIWNEHYEFVVEDSSTQHLTVKIYD 193 R + KSDPF VL+I + +++T N+LNP +++ + Q L ++D Sbjct: 38 RDVTSKSDPFCVLFIEDNGRWMEFDRTETAVNNLNPAFSKKFVLDYHFEEVQKLKFALFD 97 Query: 194 DE----GLQPSEIIGCARVDLSDIMPGKVKDVWLELVKDLEIQRDKKPRGQ 334 + L + +G L I+ K ++ + L + D KP G+ Sbjct: 98 QDKSSAQLDEHDFLGQFSCSLGTIVSSK------KITRPLLLMND-KPAGK 141
>RASL1_MOUSE (Q9Z268) RasGAP-activating-like protein 1| Length = 799 Score = 32.3 bits (72), Expect = 1.1 Identities = 29/118 (24%), Positives = 53/118 (44%), Gaps = 4/118 (3%) Frame = +2 Query: 8 EGRT---RXLVGKSDPFAVLYIRPLSAKTKKSKTINNDLNPIWNEHYEFVVEDSSTQHLT 178 EGR + + G SDP+ ++ + ++ TI L+P W E Y V HL Sbjct: 13 EGRALPAKDVSGSSDPYCLVKVD--DQVVARTATIWRSLSPFWGEEYT-VHLPLDFHHLA 69 Query: 179 VKIYDDEGLQPSEIIGCARVDLSDIMPG-KVKDVWLELVKDLEIQRDKKPRGQVHLEL 349 + D++ + +IIG + I + D W+ L + + D + +G+V L++ Sbjct: 70 FYVLDEDTVGHDDIIGKISLSKEAITADPRGIDSWINLSR---VDPDAEVQGEVCLDV 124 Score = 29.3 bits (64), Expect = 9.1 Identities = 11/28 (39%), Positives = 18/28 (64%) Frame = +2 Query: 488 GVLSVTVISAEDIPAMDVMGKADPFVVL 571 G LS+ V+ +PA DV G +DP+ ++ Sbjct: 5 GSLSIRVVEGRALPAKDVSGSSDPYCLV 32
>PLDA2_BRAOC (P55939) Phospholipase D alpha 2 precursor (EC 3.1.4.4) (PLD 2)| (Choline phosphatase 2) (Phosphatidylcholine-hydrolyzing phospholipase D 2) Length = 812 Score = 32.0 bits (71), Expect = 1.4 Identities = 26/114 (22%), Positives = 59/114 (51%), Gaps = 5/114 (4%) Frame = +2 Query: 32 GKSDPFAVLYIRPLSAKTKKSKTINND-LNPIWNEHYE-FVVEDSSTQHLTVKIYDDEGL 205 G++ +A + ++ A+ +++ I ++ NP W E + + +S TVK D+ Sbjct: 47 GETQLYATIDLQ--KARVGRTRKITDEPKNPKWYESFHIYCAHMASDIIFTVK---DDNP 101 Query: 206 QPSEIIGCARVDLSDIMPGKVKDVWLELVKDLEIQRDKKP---RGQVHLELLYY 358 + +IG A V + +++ G+ + W+E++ D D+ P ++H++L Y+ Sbjct: 102 IGATLIGRAYVPVDEVINGEEVEKWVEILDD-----DRNPIHGESKIHVKLQYF 150
>SMUF1_DROME (Q9V853) E3 ubiquitin-protein ligase Smurf1 (EC 6.3.2.-) (Smad| ubiquitination regulatory factor 1 homolog) (DSmurf) (Lethal with a checkpoint kinase protein) Length = 1061 Score = 32.0 bits (71), Expect = 1.4 Identities = 24/105 (22%), Positives = 48/105 (45%), Gaps = 1/105 (0%) Frame = +2 Query: 41 DPFAVLYIRPLSAKTKKSKTINNDLNPIWNEHYEFVVEDSSTQHLTVKIYDDEGL-QPSE 217 DPFA + + + + ++ + L+P WN HY+ + +T+ +++ + + S Sbjct: 35 DPFAKVQVDG-TGQVYSTEISKSSLDPKWNAHYDLFLGIGDA--ITITVWNQRKIHKGSG 91 Query: 218 IIGCARVDLSDIMPGKVKDVWLELVKDLEIQRDKKPRGQVHLELL 352 +GC R+ +I K + L D+ RGQ+ + LL Sbjct: 92 FLGCVRIPAFNIQSLKGAGFQRLDLGKLSPDDDELVRGQIIISLL 136
>PLDA1_BRAOC (O82549) Phospholipase D alpha 1 precursor (EC 3.1.4.4) (PLD 1)| (Choline phosphatase 1) (Phosphatidylcholine-hydrolyzing phospholipase D 1) Length = 810 Score = 31.6 bits (70), Expect = 1.8 Identities = 28/115 (24%), Positives = 54/115 (46%), Gaps = 5/115 (4%) Frame = +2 Query: 29 VGKSDPFAVLYIRPLSAKTKKSKTINNDL-NPIWNEHYE-FVVEDSSTQHLTVKIYDDEG 202 VGK + I A+ +++ I ++ NP W E + + +S TVK D+ Sbjct: 43 VGKGETQLYATIDLQRARVGRTRKIKDEAKNPKWYESFHIYCAHLASDIIFTVK---DDN 99 Query: 203 LQPSEIIGCARVDLSDIMPGKVKDVWLELVKDLEIQRDKKP---RGQVHLELLYY 358 + +IG A V + ++ G+ D W+E+ + D+ P ++H++L Y+ Sbjct: 100 PIGATLIGRAYVPVDQVIHGEEVDQWVEI-----LDNDRNPIHGGSKIHVKLQYF 149
>CPNE8_MOUSE (Q9DC53) Copine-8 (Copine VIII)| Length = 564 Score = 31.6 bits (70), Expect = 1.8 Identities = 31/146 (21%), Positives = 56/146 (38%), Gaps = 6/146 (4%) Frame = +2 Query: 32 GKSDPFAVLYIRPLSAK---TKKSKTINNDLNPIWNE---HYEFVVEDSSTQHLTVKIYD 193 GKSDPF V Y K++ + N LNP+W + + + V++YD Sbjct: 176 GKSDPFLVFYRSNEDGSFTICHKTEVVKNTLNPVWQAFKISVRALCNGDYDRTIKVEVYD 235 Query: 194 DEGLQPSEIIGCARVDLSDIMPGKVKDVWLELVKDLEIQRDKKPRGQVHLELLYYPFDKQ 373 + + IG ++ G+ + E+V + + KK + LL + + + Sbjct: 236 WDRDGSHDFIGEFTTSYRELARGQSQFNVYEVVNPKKKGKKKKYTNSGTVTLLSFLVETE 295 Query: 374 EGVSNPFASQIQLTSLEKVLKTESNG 451 + Q+ + T SNG Sbjct: 296 VSFLDYIKGGTQINFTVAIDFTASNG 321
>CPNE8_HUMAN (Q86YQ8) Copine-8 (Copine VIII)| Length = 564 Score = 31.6 bits (70), Expect = 1.8 Identities = 31/146 (21%), Positives = 56/146 (38%), Gaps = 6/146 (4%) Frame = +2 Query: 32 GKSDPFAVLYIRPLSAK---TKKSKTINNDLNPIWNE---HYEFVVEDSSTQHLTVKIYD 193 GKSDPF V Y K++ + N LNP+W + + + V++YD Sbjct: 176 GKSDPFLVFYRSNEDGSFTICHKTEVVKNTLNPVWQAFKISVRALCNGDYDRTIKVEVYD 235 Query: 194 DEGLQPSEIIGCARVDLSDIMPGKVKDVWLELVKDLEIQRDKKPRGQVHLELLYYPFDKQ 373 + + IG ++ G+ + E+V + + KK + LL + + + Sbjct: 236 WDRDGSHDFIGEFTTSYRELSRGQSQFNVYEVVNPKKKGKKKKYTNSGTVTLLSFLVETE 295 Query: 374 EGVSNPFASQIQLTSLEKVLKTESNG 451 + Q+ + T SNG Sbjct: 296 VSFLDYIKGGTQINFTVAIDFTASNG 321 Score = 29.6 bits (65), Expect = 6.9 Identities = 18/69 (26%), Positives = 32/69 (46%), Gaps = 4/69 (5%) Frame = +2 Query: 20 RXLVGKSDPFAVLYIRPLSAKT----KKSKTINNDLNPIWNEHYEFVVEDSSTQHLTVKI 187 R KSDP VLY++ + K +++ I+N LNP + + ++L + Sbjct: 38 RDTFSKSDPICVLYVQGVGNKEWREFGRTEVIDNTLNPDFVRKFILDYFFEERENLRFDL 97 Query: 188 YDDEGLQPS 214 YD + P+ Sbjct: 98 YDVDSKSPN 106
>CPNE5_MOUSE (Q8JZW4) Copine-5 (Copine V)| Length = 593 Score = 31.2 bits (69), Expect = 2.4 Identities = 30/146 (20%), Positives = 56/146 (38%), Gaps = 6/146 (4%) Frame = +2 Query: 32 GKSDPFAVLYIRPLSAK---TKKSKTINNDLNPIWNEH---YEFVVEDSSTQHLTVKIYD 193 GKSDPF V Y K++ + N LNP+W + + + V++YD Sbjct: 195 GKSDPFLVFYRSNEDGTFTICHKTEVMKNTLNPVWQTFSIPVRALCNGDYDRTIKVEVYD 254 Query: 194 DEGLQPSEIIGCARVDLSDIMPGKVKDVWLELVKDLEIQRDKKPRGQVHLELLYYPFDKQ 373 + + IG ++ G+ + E++ + + KK + LL + + + Sbjct: 255 WDRDGSHDFIGEFTTSYRELARGQSQFNIYEVINPKKKMKKKKYVNSGTVTLLSFAVESE 314 Query: 374 EGVSNPFASQIQLTSLEKVLKTESNG 451 + Q+ + T SNG Sbjct: 315 STFLDYIKGGTQINFTVAIDFTASNG 340
>SYT8_MOUSE (Q9R0N6) Synaptotagmin-8 (Synaptotagmin VIII) (SytVIII)| Length = 395 Score = 31.2 bits (69), Expect = 2.4 Identities = 20/88 (22%), Positives = 42/88 (47%), Gaps = 2/88 (2%) Frame = +2 Query: 32 GKSDPFAVLYIRPLSAKTKKSKTINNDLNPIWNEHYEFVVEDSSTQHLTVKI--YDDEGL 205 G +DP+A + + S + ++K L+P++ E F+V + T+K+ +D + Sbjct: 144 GTADPYAWVSVSTQSGRRHETKVHRGTLSPMFEETCCFLVPPAELPKATLKVQLWDFKRF 203 Query: 206 QPSEIIGCARVDLSDIMPGKVKDVWLEL 289 E +G ++ L + V + W +L Sbjct: 204 SEHEPLGELQLPLGTVDLQHVLESWYQL 231
>CO3_EPTBU (P98094) Complement C3 [Contains: Complement C3 beta chain;| Complement C3 alpha chain; C3a anaphylatoxin; Complement C3 gamma chain] (Fragment) Length = 1620 Score = 30.8 bits (68), Expect = 3.1 Identities = 18/54 (33%), Positives = 26/54 (48%) Frame = -2 Query: 591 VSPFFRYRTTNGSAFPITSIAGMSSADITVTERTPLVITFFLWLTSYPLDSVLR 430 V P + N S I + GM +A ++RT V+T W +PL+SV R Sbjct: 1546 VIPMHCGKNLNVSPGDIYLVMGMHNAHWRNSDRTQYVLTSDTWFEKFPLESVCR 1599
>CPNE3_MOUSE (Q8BT60) Copine-3 (Copine III)| Length = 533 Score = 30.8 bits (68), Expect = 3.1 Identities = 27/110 (24%), Positives = 49/110 (44%), Gaps = 7/110 (6%) Frame = +2 Query: 26 LVGKSDPFAVLYIRPLSAK---TKKSKTINNDLNPIWNEHYEFVVEDSSTQHLTVKIYDD 196 + KSDP VL++ + ++++ I N LNP +++ + Q L IYD Sbjct: 23 VTSKSDPLCVLFLNTSGHQWYEVERTERIKNSLNPKFSKTFVIDYYFEVVQKLKFGIYDI 82 Query: 197 EG----LQPSEIIGCARVDLSDIMPGKVKDVWLELVKDLEIQRDKKPRGQ 334 + L + +G V L I+ K +L + L + ++ KP G+ Sbjct: 83 DNKTIELSDDDFLGECEVTLGQIVSSK------KLTRPL-VLKNGKPAGK 125
>PLDA2_ARATH (Q9SSQ9) Phospholipase D alpha 2 (EC 3.1.4.4) (AtPLDalpha2) (PLD| alpha 2) (Choline phosphatase 2) (Phosphatidylcholine-hydrolyzing phospholipase D 2) Length = 810 Score = 30.4 bits (67), Expect = 4.1 Identities = 25/120 (20%), Positives = 55/120 (45%), Gaps = 4/120 (3%) Frame = +2 Query: 29 VGKSDPFAVLYIRPLSAKTKKSKTINND-LNPIWNEHYEFVVEDSSTQHLTVKIYDDEGL 205 VGK + I A+ +++ I + NP W E + + +H+ + D + Sbjct: 43 VGKGETQLYATIDLEKARVGRTRKITKEPKNPKWFESFHIYCGHMA-KHVIFTVKDANPI 101 Query: 206 QPSEIIGCARVDLSDIMPGKVKDVWLELVKDLEIQRDKKP---RGQVHLELLYYPFDKQE 376 + +IG + + DI+ G+ D W+++ + +K P ++H++L Y+ +K + Sbjct: 102 GAT-LIGRGYIPVEDILHGEEVDRWVDI-----LDNEKNPIAGGSKIHVKLQYFGVEKDK 155
>UN13D_HUMAN (Q70J99) Unc-13 homolog D (Munc13-4)| Length = 1090 Score = 30.4 bits (67), Expect = 4.1 Identities = 24/75 (32%), Positives = 35/75 (46%), Gaps = 13/75 (17%) Frame = +2 Query: 32 GKSDPFAVLYIRP-------LSAKTKKSKTINNDLNPIWNEHYEFVVEDSSTQH------ 172 G SDPF L + P + +T+K K DL+P+++E +EF+V + Sbjct: 944 GSSDPFVQLTLEPRHEFPELAARETQKHK---KDLHPLFDETFEFLVPAEPCRKAGACLL 1000 Query: 173 LTVKIYDDEGLQPSE 217 LTV YD G E Sbjct: 1001 LTVLDYDTLGADDLE 1015
>CPNE5_HUMAN (Q9HCH3) Copine-5 (Copine V)| Length = 593 Score = 30.0 bits (66), Expect = 5.3 Identities = 31/146 (21%), Positives = 56/146 (38%), Gaps = 6/146 (4%) Frame = +2 Query: 32 GKSDPFAVLYIRPLSAK---TKKSKTINNDLNPIWNEH---YEFVVEDSSTQHLTVKIYD 193 GKSDPF V Y K++ + N LNP+W + + + V++YD Sbjct: 195 GKSDPFLVFYRSNEDGTFTICHKTEVMKNTLNPVWQTFSIPVRALCNGDYDRTIKVEVYD 254 Query: 194 DEGLQPSEIIGCARVDLSDIMPGKVKDVWLELVKDLEIQRDKKPRGQVHLELLYYPFDKQ 373 + + IG ++ G+ + E+V + + KK + LL + + + Sbjct: 255 WDRDGSHDFIGEFTTSYRELARGQSQFNIYEVVNPKKKMKKKKYVNSGTVTLLSFAVESE 314 Query: 374 EGVSNPFASQIQLTSLEKVLKTESNG 451 + Q+ + T SNG Sbjct: 315 CTFLDYIKGGTQINFTVAIDFTASNG 340
>SYT12_RAT (P97610) Synaptotagmin-12 (Synaptotagmin XII) (SytXII)| (Synaptotagmin-related gene 1 protein) (Srg1) Length = 421 Score = 30.0 bits (66), Expect = 5.3 Identities = 17/52 (32%), Positives = 27/52 (51%), Gaps = 2/52 (3%) Frame = +2 Query: 38 SDPFAVLYIRPLSAKTKKSKTI--NNDLNPIWNEHYEFVVEDSSTQHLTVKI 187 +DPF +Y+ K K KT +D NP++NE F V Q L++++ Sbjct: 319 ADPFVKVYLLQDGRKMSKKKTAVKRDDPNPVFNEAMIFSVPAIVLQDLSLRV 370
>SYT12_MOUSE (Q920N7) Synaptotagmin-12 (Synaptotagmin XII) (SytXII)| Length = 421 Score = 30.0 bits (66), Expect = 5.3 Identities = 17/52 (32%), Positives = 27/52 (51%), Gaps = 2/52 (3%) Frame = +2 Query: 38 SDPFAVLYIRPLSAKTKKSKTI--NNDLNPIWNEHYEFVVEDSSTQHLTVKI 187 +DPF +Y+ K K KT +D NP++NE F V Q L++++ Sbjct: 319 ADPFVKVYLLQDGRKMSKKKTAVKRDDPNPVFNEAMIFSVPAIVLQDLSLRV 370
>SYT12_HUMAN (Q8IV01) Synaptotagmin-12 (Synaptotagmin XII) (SytXII)| Length = 421 Score = 30.0 bits (66), Expect = 5.3 Identities = 17/52 (32%), Positives = 27/52 (51%), Gaps = 2/52 (3%) Frame = +2 Query: 38 SDPFAVLYIRPLSAKTKKSKTI--NNDLNPIWNEHYEFVVEDSSTQHLTVKI 187 +DPF +Y+ K K KT +D NP++NE F V Q L++++ Sbjct: 319 ADPFVKVYLLQDGRKMSKKKTAVKRDDPNPVFNEAMIFSVPAIVLQDLSLRV 370
>YE56_CAEEL (P90747) Probable cation-transporting ATPase C10C6.6 in chromosome| IV (EC 3.6.3.-) Length = 1178 Score = 30.0 bits (66), Expect = 5.3 Identities = 17/63 (26%), Positives = 34/63 (53%) Frame = +2 Query: 278 WLELVKDLEIQRDKKPRGQVHLELLYYPFDKQEGVSNPFASQIQLTSLEKVLKTESNGYD 457 W ELVK + RDK+ + + ++Y +D++ S F ++ T+ V +S+G++ Sbjct: 103 WPELVKLMRTTRDKQTKLWFEFQRVHYTWDEE---SREFQTKTLDTAKPMVFFQKSHGFE 159 Query: 458 VNQ 466 V + Sbjct: 160 VEE 162
>SSRP1_ARATH (Q05153) Structure-specific recognition protein 1 homolog (HMG| protein) Length = 646 Score = 30.0 bits (66), Expect = 5.3 Identities = 28/96 (29%), Positives = 50/96 (52%) Frame = +2 Query: 143 FVVEDSSTQHLTVKIYDDEGLQPSEIIGCARVDLSDIMPGKVKDVWLELVKDLEIQRDKK 322 F + +S+TQ + DE PS++ V ++D+ PG V+D V E Sbjct: 170 FHIPNSNTQFV-----GDENRPPSQVFNDTIVAMADVSPG-VEDA----VVTFESIAILT 219 Query: 323 PRGQVHLELLYYPFDKQEGVSNPFASQIQLTSLEKV 430 PRG+ ++E L+ F + +G +N F +IQ +S+ ++ Sbjct: 220 PRGRYNVE-LHLSFLRLQGQANDF--KIQYSSVVRL 252
>RIMS2_MOUSE (Q9EQZ7) Regulating synaptic membrane exocytosis protein 2| (Rab3-interacting molecule 2) (RIM 2) (Rab3-interacting protein 2) Length = 1530 Score = 29.6 bits (65), Expect = 6.9 Identities = 45/198 (22%), Positives = 81/198 (40%), Gaps = 15/198 (7%) Frame = +2 Query: 2 RHEGRTRXLVGKSDPFAVLYIRP-LSAKTKK-SKTINNDLNPIWNEHYEFVV---EDSST 166 R +GR R +P+ +Y P S K K+ +KT+ L P WN+ + + + Sbjct: 844 REDGRPR------NPYVKIYFLPDRSDKNKRRTKTVKKTLEPKWNQTFIYSPVHRREFRE 897 Query: 167 QHLTVKIYDDEGL--QPSEIIGCARVDLSDIMPGKVKDVWLEL----VKDLEIQRDKK-- 322 + L + ++D + + SE +G ++L + + W +L V L + R Sbjct: 898 RMLEITLWDQARVREEESEFLGEILIELETALLDD-EPHWYKLQTHDVSSLPLPRPSPYL 956 Query: 323 PRGQVHLELLYYPFDKQEGVSNPFASQIQL-TSLEKVLKTESNGYDVNQRKNVITRGVLS 499 PR Q+H E + + +S+ S + V NG D+ + V+S Sbjct: 957 PRRQLHGESPTRRLQRSKRISDSEVSDYDCEDGVGVVSDYRHNGRDLQSSTLSVPEQVMS 1016 Query: 500 VTVISAEDIP-AMDVMGK 550 S P +DV+G+ Sbjct: 1017 SNHCSPSGSPHRVDVIGR 1034
>Y864_MYCCT (P43047) Hypothetical protein MCAP_0864 precursor (ORF R8)| Length = 470 Score = 29.6 bits (65), Expect = 6.9 Identities = 29/129 (22%), Positives = 61/129 (47%) Frame = +2 Query: 86 KKSKTINNDLNPIWNEHYEFVVEDSSTQHLTVKIYDDEGLQPSEIIGCARVDLSDIMPGK 265 K+ K+INND+N NE ++ED ++ K ++ Q + D ++ Sbjct: 46 KQLKSINNDINIKENELKSLLLEDEKNL-ISSKDKINKLKQEQRDLVKKDFDQKQMISKL 104 Query: 266 VKDVWLELVKDLEIQRDKKPRGQVHLELLYYPFDKQEGVSNPFASQIQLTSLEKVLKTES 445 KD+ L + E ++D+K + + L L ++ + + F +I+ +++ LK ++ Sbjct: 105 TKDL-TNLKLESETKKDQKAKVESELNNLKKTRKHKDELKDYFNKEIK--NIQSELKNKT 161 Query: 446 NGYDVNQRK 472 N + N+ K Sbjct: 162 NEFTTNETK 170
>CLCA_PSEPU (P11451) Chlorocatechol 1,2-dioxygenase (EC 1.13.11.-)| Length = 260 Score = 29.6 bits (65), Expect = 6.9 Identities = 14/46 (30%), Positives = 23/46 (50%) Frame = +2 Query: 143 FVVEDSSTQHLTVKIYDDEGLQPSEIIGCARVDLSDIMPGKVKDVW 280 + +E + +K YD + +P I G R D +++ G V DVW Sbjct: 77 YFLEGAPVVEGVLKTYDTDDHKPLIIRGTVRSDTGELLAGAVIDVW 122
>NIKA_ECOLI (P33590) Nickel-binding periplasmic protein precursor (EC 3.6.3.24)| Length = 524 Score = 29.3 bits (64), Expect = 9.1 Identities = 13/49 (26%), Positives = 26/49 (53%), Gaps = 1/49 (2%) Frame = +2 Query: 251 IMPGKVKDVWLELVKDL-EIQRDKKPRGQVHLELLYYPFDKQEGVSNPF 394 ++ + + WLEL + +++ K Q+ L+ YYPF ++ + PF Sbjct: 113 VLDNRQRHAWLELANQIVDVKALSKTELQITLKSAYYPFLQELALPRPF 161
>LPG1_LEIDO (Q05889) Galactofuranosyl glycosyltransferase (EC 2.4.1.-)| Length = 434 Score = 29.3 bits (64), Expect = 9.1 Identities = 18/63 (28%), Positives = 31/63 (49%) Frame = +2 Query: 179 VKIYDDEGLQPSEIIGCARVDLSDIMPGKVKDVWLELVKDLEIQRDKKPRGQVHLELLYY 358 V IY D G P G +D+ + + + +W E+ +++ RD KP ++LL + Sbjct: 374 VTIYQDTGRNPLPFNGTIPLDMWVLDTDRRRSIW-EIGENIRCHRDYKP---YSMKLLDF 429 Query: 359 PFD 367 P D Sbjct: 430 PVD 432
>CPNE2_HUMAN (Q96FN4) Copine-2 (Copine II)| Length = 548 Score = 29.3 bits (64), Expect = 9.1 Identities = 16/62 (25%), Positives = 30/62 (48%), Gaps = 2/62 (3%) Frame = +2 Query: 20 RXLVGKSDPFAVLYIRPLS--AKTKKSKTINNDLNPIWNEHYEFVVEDSSTQHLTVKIYD 193 R + KSDPF VL+ + +++T N+LNP +++ + Q L ++D Sbjct: 38 RDVTSKSDPFCVLFTENNGRWIEYDRTETAINNLNPAFSKKFVLDYHFEEVQKLKFALFD 97 Query: 194 DE 199 + Sbjct: 98 QD 99
>PLCD1_MOUSE (Q8R3B1) 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase| delta 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-delta-1) (Phospholipase C-delta-1) (PLC-III) Length = 756 Score = 29.3 bits (64), Expect = 9.1 Identities = 17/77 (22%), Positives = 32/77 (41%), Gaps = 3/77 (3%) Frame = +2 Query: 41 DPFAVLYIRPLSAKTKKSKTI---NNDLNPIWNEHYEFVVEDSSTQHLTVKIYDDEGLQP 211 DP ++ I + +T NN NP W+ +EFVV + + D + Sbjct: 653 DPKVIVEIHGVGQDVASRQTAVITNNGFNPRWDTEFEFVVAVPDLALVRFMVEDYDSSSK 712 Query: 212 SEIIGCARVDLSDIMPG 262 ++ IG + + + + G Sbjct: 713 NDFIGQSTIPWNSLKQG 729
>LEU2_BACTN (Q8A6L7) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 464 Score = 29.3 bits (64), Expect = 9.1 Identities = 16/56 (28%), Positives = 23/56 (41%) Frame = +2 Query: 101 INNDLNPIWNEHYEFVVEDSSTQHLTVKIYDDEGLQPSEIIGCARVDLSDIMPGKV 268 +N + IW+ H VED TQ ++Y E P G + + P KV Sbjct: 1 MNTLFDKIWDAHVVTTVEDGPTQLYIDRLYCHEVTSPQAFAGLRERGIKVLRPEKV 56
>STP2_MOUSE (P11378) Nuclear transition protein 2 (TP-2) (TP2)| Length = 117 Score = 29.3 bits (64), Expect = 9.1 Identities = 24/74 (32%), Positives = 34/74 (45%), Gaps = 11/74 (14%) Frame = -3 Query: 296 LSQVPTKHP*PFQA*YPISLHERSQ*SLTAGALHRRKFSQSG-AG*MS----------PR 150 + +PT HP P + P S H +Q + + H R SQ+G AG S P+ Sbjct: 5 MQSLPTTHPHPHSSSRPQS-HTSNQCNQCTCSHHCRSCSQAGHAGSSSSPSPGPPMKHPK 63 Query: 149 PQIHSVHSRWGSNH 108 P +HS HS +H Sbjct: 64 PSVHSRHSPARPSH 77 Database: uniprot_sprot.fasta Posted date: May 25, 2006 5:36 PM Number of letters in database: 80,573,946 Number of sequences in database: 219,361 Lambda K H 0.318 0.135 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 90,505,737 Number of Sequences: 219361 Number of extensions: 1928416 Number of successful extensions: 5579 Number of sequences better than 10.0: 185 Number of HSP's better than 10.0 without gapping: 5161 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 5547 length of database: 80,573,946 effective HSP length: 107 effective length of database: 57,102,319 effective search space used: 5253413348 frameshift window, decay const: 50, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
