>MIOX_ORYSA (Q5Z8T3) Probable inositol oxygenase (EC 1.13.99.1) (Myo-inositol|
           oxygenase)
          Length = 308

 Score =  337 bits (864), Expect = 2e-92
 Identities = 153/166 (92%), Positives = 158/166 (95%)
 Frame = -2

Query: 707 IHDLGKVLLHPSFGELPQWAVVGDTFPVGCAFDECNVHFKYLKENPDYHNPEFNTKFGVY 528
           IHDLGKVLLHPSFGELPQW+VVGDTFPVGCAFDECNVHFKY KENPDY NP+ NTKFG Y
Sbjct: 143 IHDLGKVLLHPSFGELPQWSVVGDTFPVGCAFDECNVHFKYFKENPDYLNPKLNTKFGAY 202

Query: 527 SEGCGLDNVLMSWGHDDYMYLVAKENKTTLPSAGLFIIRYHSFYPLHKHGAYTHLMNEED 348
           SEGCGLDNVLMSWGHDDYMYLVAKENKTTLPSAGLFIIRYHSFYPLHKHGAY HLMN+ED
Sbjct: 203 SEGCGLDNVLMSWGHDDYMYLVAKENKTTLPSAGLFIIRYHSFYPLHKHGAYMHLMNDED 262

Query: 347 KENLKWLHVFNKYDLYSKSSVRIDVEKVKPYYMSLIEKYFPEKLKW 210
           KENLKWL VFNKYDLYSKS+ RIDVEKVKPYYMSLIEKYFP KL+W
Sbjct: 263 KENLKWLRVFNKYDLYSKSNERIDVEKVKPYYMSLIEKYFPAKLRW 308

>MIOX5_ARATH (Q9FJU4) Inositol oxygenase 5 (EC 1.13.99.1) (Myo-inositol|
           oxygenase 5) (AtMIOX5)
          Length = 314

 Score =  310 bits (793), Expect = 4e-84
 Identities = 140/166 (84%), Positives = 151/166 (90%)
 Frame = -2

Query: 707 IHDLGKVLLHPSFGELPQWAVVGDTFPVGCAFDECNVHFKYLKENPDYHNPEFNTKFGVY 528
           IHDLGKVL  P FG LPQWAVVGDTFPVGCAFDE NVH KY  ENPD++NP++NTK G+Y
Sbjct: 149 IHDLGKVLTLPQFGGLPQWAVVGDTFPVGCAFDESNVHHKYFMENPDFNNPKYNTKAGIY 208

Query: 527 SEGCGLDNVLMSWGHDDYMYLVAKENKTTLPSAGLFIIRYHSFYPLHKHGAYTHLMNEED 348
           SEGCGL+NVLMSWGHDDYMYLVAKEN +TLPS GLFIIRYHSFYPLHK GAYTHLMNEED
Sbjct: 209 SEGCGLENVLMSWGHDDYMYLVAKENGSTLPSPGLFIIRYHSFYPLHKAGAYTHLMNEED 268

Query: 347 KENLKWLHVFNKYDLYSKSSVRIDVEKVKPYYMSLIEKYFPEKLKW 210
           KENLKWLHVFNKYDLYSKS V ++VEKVKPYYMSLI+KYFPE L+W
Sbjct: 269 KENLKWLHVFNKYDLYSKSKVHVNVEKVKPYYMSLIKKYFPENLRW 314

>MIOX1_ARATH (Q8L799) Inositol oxygenase 1 (EC 1.13.99.1) (Myo-inositol|
           oxygenase 1) (AtMIOX1)
          Length = 311

 Score =  304 bits (779), Expect = 2e-82
 Identities = 137/166 (82%), Positives = 149/166 (89%)
 Frame = -2

Query: 707 IHDLGKVLLHPSFGELPQWAVVGDTFPVGCAFDECNVHFKYLKENPDYHNPEFNTKFGVY 528
           IHDLGKVLLH SFGELPQWAVVGDTFPVGCAFDE  VH KY KENPDY NP +N+K+G+Y
Sbjct: 146 IHDLGKVLLHSSFGELPQWAVVGDTFPVGCAFDESIVHHKYFKENPDYDNPSYNSKYGIY 205

Query: 527 SEGCGLDNVLMSWGHDDYMYLVAKENKTTLPSAGLFIIRYHSFYPLHKHGAYTHLMNEED 348
           +EGCGLDNVLMSWGHDDYMYLVAKEN+TTLPSAGLFIIRYHSFY LHK  AY HLMN ED
Sbjct: 206 TEGCGLDNVLMSWGHDDYMYLVAKENQTTLPSAGLFIIRYHSFYALHKSEAYKHLMNNED 265

Query: 347 KENLKWLHVFNKYDLYSKSSVRIDVEKVKPYYMSLIEKYFPEKLKW 210
           +EN+KWL VFNKYDLYSKS VR++VE+VKPYY+SL  KYFP KLKW
Sbjct: 266 RENMKWLKVFNKYDLYSKSKVRVNVEEVKPYYLSLTNKYFPSKLKW 311

>MIOX4_ARATH (Q8H1S0) Inositol oxygenase 4 (EC 1.13.99.1) (Myo-inositol|
           oxygenase 4) (AtMIOX4)
          Length = 317

 Score =  303 bits (776), Expect = 3e-82
 Identities = 137/166 (82%), Positives = 147/166 (88%)
 Frame = -2

Query: 707 IHDLGKVLLHPSFGELPQWAVVGDTFPVGCAFDECNVHFKYLKENPDYHNPEFNTKFGVY 528
           IHDLGKV+  P FG LPQWAVVGDTFPVGCAFDE NVH KY  ENPD+HN  +NTK G+Y
Sbjct: 152 IHDLGKVITLPQFGGLPQWAVVGDTFPVGCAFDESNVHHKYFVENPDFHNETYNTKNGIY 211

Query: 527 SEGCGLDNVLMSWGHDDYMYLVAKENKTTLPSAGLFIIRYHSFYPLHKHGAYTHLMNEED 348
           SEGCGL+NV+MSWGHDDYMYLVAKEN +TLPSAG FIIRYHSFYPLH  G YTHLMNEED
Sbjct: 212 SEGCGLNNVMMSWGHDDYMYLVAKENGSTLPSAGQFIIRYHSFYPLHTAGEYTHLMNEED 271

Query: 347 KENLKWLHVFNKYDLYSKSSVRIDVEKVKPYYMSLIEKYFPEKLKW 210
           KENLKWLHVFNKYDLYSKS V +DVEKVKPYYMSLI+KYFPE L+W
Sbjct: 272 KENLKWLHVFNKYDLYSKSKVHVDVEKVKPYYMSLIKKYFPENLRW 317

>MIOX2_ARATH (O82200) Inositol oxygenase 2 (EC 1.13.99.1) (Myo-inositol|
           oxygenase 2) (AtMIOX2)
          Length = 317

 Score =  296 bits (758), Expect = 4e-80
 Identities = 134/166 (80%), Positives = 147/166 (88%)
 Frame = -2

Query: 707 IHDLGKVLLHPSFGELPQWAVVGDTFPVGCAFDECNVHFKYLKENPDYHNPEFNTKFGVY 528
           IHDLGKVLL P FG LPQWAVVGDTFPVGC FD  N+H KY K N D +NP++NTK GVY
Sbjct: 152 IHDLGKVLLLPEFGGLPQWAVVGDTFPVGCTFDSANIHHKYFKGNHDINNPKYNTKNGVY 211

Query: 527 SEGCGLDNVLMSWGHDDYMYLVAKENKTTLPSAGLFIIRYHSFYPLHKHGAYTHLMNEED 348
           +EGCGLDNVLMSWGHDDYMYLVAK+N TTLP AGLFIIRYHSFYPLHK GAYTHLMN+ED
Sbjct: 212 TEGCGLDNVLMSWGHDDYMYLVAKKNGTTLPHAGLFIIRYHSFYPLHKAGAYTHLMNDED 271

Query: 347 KENLKWLHVFNKYDLYSKSSVRIDVEKVKPYYMSLIEKYFPEKLKW 210
           +++LKWLHVFNKYDLYSKS V +DVE+VKPYY+SLI KYFP KLKW
Sbjct: 272 RDDLKWLHVFNKYDLYSKSKVLVDVEQVKPYYISLINKYFPAKLKW 317

>MIOX_BRARE (Q4V8T0) Inositol oxygenase (EC 1.13.99.1) (Myo-inositol oxygenase)|
          Length = 278

 Score =  197 bits (502), Expect = 2e-50
 Identities = 94/167 (56%), Positives = 118/167 (70%), Gaps = 1/167 (0%)
 Frame = -2

Query: 707 IHDLGKVLLHPSFGELPQWAVVGDTFPVGCAFDECNVHFKYLKE-NPDYHNPEFNTKFGV 531
           IHD+GKV+   +    PQWAVVGDT+PVGC F    V      E NPD  NP  NT+FG+
Sbjct: 115 IHDVGKVM---ALYSEPQWAVVGDTYPVGCKFQNSIVFRNSTFEGNPDGKNPAPNTEFGI 171

Query: 530 YSEGCGLDNVLMSWGHDDYMYLVAKENKTTLPSAGLFIIRYHSFYPLHKHGAYTHLMNEE 351
           Y   CGLD VLMSWGHD+Y+Y V K NK T+P  GL++IR+HSFYP H +G Y HL NE+
Sbjct: 172 YEPQCGLDKVLMSWGHDEYLYRVMKFNKCTIPEEGLYMIRFHSFYPWHSNGDYMHLCNEK 231

Query: 350 DKENLKWLHVFNKYDLYSKSSVRIDVEKVKPYYMSLIEKYFPEKLKW 210
           D++ L W+  FNK+DLY+KS+   DVE++KPYY SLI+KY P  L+W
Sbjct: 232 DQQMLPWVKEFNKFDLYTKSTELPDVERLKPYYQSLIDKYCPGVLQW 278

>MIOX_PIG (Q8WN98) Inositol oxygenase (EC 1.13.99.1) (Myo-inositol oxygenase)|
           (Aldehyde reductase-like 6)
          Length = 282

 Score =  179 bits (453), Expect = 1e-44
 Identities = 88/168 (52%), Positives = 114/168 (67%), Gaps = 2/168 (1%)
 Frame = -2

Query: 707 IHDLGKVLLHPSFGELPQWAVVGDTFPVGCAFDECNVHF--KYLKENPDYHNPEFNTKFG 534
           +HDLGKVL+    GE PQWAVVGDTFPVGC   + +V F     ++NPD  +P ++T+ G
Sbjct: 119 LHDLGKVLVLA--GE-PQWAVVGDTFPVGCR-PQASVVFCDSTFQDNPDLQDPVYSTELG 174

Query: 533 VYSEGCGLDNVLMSWGHDDYMYLVAKENKTTLPSAGLFIIRYHSFYPLHKHGAYTHLMNE 354
           +Y   CGL+N LMSWGHD+YMY + K NK +LP    +IIR+HSFYP H  G Y  L NE
Sbjct: 175 MYQPHCGLENALMSWGHDEYMYQMMKFNKFSLPGEAFYIIRFHSFYPWHTGGDYRQLCNE 234

Query: 353 EDKENLKWLHVFNKYDLYSKSSVRIDVEKVKPYYMSLIEKYFPEKLKW 210
           +D   L W+  FNK+DLY+K S   DV++++PYY  LI+KY P  L W
Sbjct: 235 QDLAMLPWVQEFNKFDLYTKGSDMPDVDELRPYYQGLIDKYCPGVLCW 282

>MIOX_MOUSE (Q9QXN5) Inositol oxygenase (EC 1.13.99.1) (Myo-inositol oxygenase)|
           (Aldehyde reductase-like 6) (Renal-specific
           oxidoreductase)
          Length = 285

 Score =  177 bits (449), Expect = 3e-44
 Identities = 84/168 (50%), Positives = 115/168 (68%), Gaps = 2/168 (1%)
 Frame = -2

Query: 707 IHDLGKVLLHPSFGELPQWAVVGDTFPVGCAFDECNVHF--KYLKENPDYHNPEFNTKFG 534
           +HDLGK++    +GE PQWAVVGDTFPVGC   + +V F     ++NPD  +P ++T+ G
Sbjct: 122 LHDLGKIMA--LWGE-PQWAVVGDTFPVGCR-PQASVVFCDSTFQDNPDLQDPRYSTELG 177

Query: 533 VYSEGCGLDNVLMSWGHDDYMYLVAKENKTTLPSAGLFIIRYHSFYPLHKHGAYTHLMNE 354
           +Y   CGL+NVLMSWGHD+Y+Y + K NK +LPS   ++IR+HSFYP H  G Y  L ++
Sbjct: 178 MYQPHCGLENVLMSWGHDEYLYQMMKFNKFSLPSEAFYMIRFHSFYPWHTGGDYRQLCSQ 237

Query: 353 EDKENLKWLHVFNKYDLYSKSSVRIDVEKVKPYYMSLIEKYFPEKLKW 210
           +D + L W+  FNK+DLY+K     DVE ++PYY  LI+KY P  L W
Sbjct: 238 QDLDMLPWVQEFNKFDLYTKCPDLPDVESLRPYYQGLIDKYCPGTLSW 285

>MIOX_PONPY (Q5REY9) Inositol oxygenase (EC 1.13.99.1) (Myo-inositol oxygenase)|
          Length = 285

 Score =  176 bits (447), Expect = 5e-44
 Identities = 87/168 (51%), Positives = 112/168 (66%), Gaps = 2/168 (1%)
 Frame = -2

Query: 707 IHDLGKVLLHPSFGELPQWAVVGDTFPVGCAFDECNVHF--KYLKENPDYHNPEFNTKFG 534
           +HDLGKVL    FGE PQWAVVGDTFPVGC   + +V F     ++NPD  +P ++T+ G
Sbjct: 122 LHDLGKVLA--LFGE-PQWAVVGDTFPVGCR-PQASVVFCDSTFQDNPDLQDPRYSTELG 177

Query: 533 VYSEGCGLDNVLMSWGHDDYMYLVAKENKTTLPSAGLFIIRYHSFYPLHKHGAYTHLMNE 354
           +Y   CGLD VLMSWGHD+YMY V K NK +LP    ++IR+HSFYP H    Y  L ++
Sbjct: 178 MYQPHCGLDRVLMSWGHDEYMYQVMKFNKFSLPPEAFYMIRFHSFYPWHTGSDYQQLCSQ 237

Query: 353 EDKENLKWLHVFNKYDLYSKSSVRIDVEKVKPYYMSLIEKYFPEKLKW 210
           +D   L W+  FNK+DLY+K     DV+K++PYY  LI+KY P  L W
Sbjct: 238 QDLAMLPWVQEFNKFDLYTKCPDLPDVDKLRPYYQGLIDKYCPGILSW 285

>MIOX_HUMAN (Q9UGB7) Inositol oxygenase (EC 1.13.99.1) (Myo-inositol oxygenase)|
           (Aldehyde reductase-like 6) (Renal-specific
           oxidoreductase) (Kidney-specific protein 32)
          Length = 285

 Score =  176 bits (445), Expect = 8e-44
 Identities = 87/168 (51%), Positives = 112/168 (66%), Gaps = 2/168 (1%)
 Frame = -2

Query: 707 IHDLGKVLLHPSFGELPQWAVVGDTFPVGCAFDECNVHF--KYLKENPDYHNPEFNTKFG 534
           +HDLGKVL    FGE PQWAVVGDTFPVGC   + +V F     ++NPD  +P ++T+ G
Sbjct: 122 LHDLGKVLA--LFGE-PQWAVVGDTFPVGCR-PQASVVFCDSTFQDNPDLQDPRYSTELG 177

Query: 533 VYSEGCGLDNVLMSWGHDDYMYLVAKENKTTLPSAGLFIIRYHSFYPLHKHGAYTHLMNE 354
           +Y   CGLD VLMSWGHD+YMY V K NK +LP    ++IR+HSFYP H    Y  L ++
Sbjct: 178 MYQPHCGLDRVLMSWGHDEYMYQVMKFNKFSLPPEAFYMIRFHSFYPWHTGRDYQQLCSQ 237

Query: 353 EDKENLKWLHVFNKYDLYSKSSVRIDVEKVKPYYMSLIEKYFPEKLKW 210
           +D   L W+  FNK+DLY+K     DV+K++PYY  LI+KY P  L W
Sbjct: 238 QDLAMLPWVREFNKFDLYTKCPDLPDVDKLRPYYQGLIDKYCPGILSW 285

>MIOX_RAT (Q9QXN4) Inositol oxygenase (EC 1.13.99.1) (Myo-inositol oxygenase)|
           (Aldehyde reductase-like 6) (Renal-specific
           oxidoreductase) (Kidney-specific protein 32)
          Length = 285

 Score =  174 bits (440), Expect = 3e-43
 Identities = 82/168 (48%), Positives = 115/168 (68%), Gaps = 2/168 (1%)
 Frame = -2

Query: 707 IHDLGKVLLHPSFGELPQWAVVGDTFPVGCAFDECNVHF--KYLKENPDYHNPEFNTKFG 534
           +HDLGK+L    +GE PQWAVVGDTFPVGC   + +V F     ++NPD  +P ++T+ G
Sbjct: 122 LHDLGKILA--LWGE-PQWAVVGDTFPVGCR-PQASVVFCDSTFQDNPDLQDPRYSTELG 177

Query: 533 VYSEGCGLDNVLMSWGHDDYMYLVAKENKTTLPSAGLFIIRYHSFYPLHKHGAYTHLMNE 354
           +Y   CGL+NVLMSWGHD+Y+Y + K NK +LPS   +++R+HSFYP H  G Y  L ++
Sbjct: 178 MYQPHCGLENVLMSWGHDEYLYQMMKFNKFSLPSEAFYMVRFHSFYPWHTGGDYRQLCSQ 237

Query: 353 EDKENLKWLHVFNKYDLYSKSSVRIDVEKVKPYYMSLIEKYFPEKLKW 210
           +D + L W+  FNK+DLY+K     +V+ ++PYY  LI+KY P  L W
Sbjct: 238 QDLDMLPWVQEFNKFDLYTKCPDLPEVKSLRPYYQGLIDKYCPGILSW 285

>TRUD_GEOMG (Q39R76) tRNA pseudouridine synthase D (EC 5.4.99.-) (tRNA-uridine|
           isomerase D) (tRNA pseudouridylate synthase D)
          Length = 404

 Score = 34.3 bits (77), Expect = 0.38
 Identities = 18/45 (40%), Positives = 23/45 (51%)
 Frame = -1

Query: 705 PRSGQGAAASQLRGASSVGSRR*HLPRGLRVRRMQRPLQVPQGEP 571
           P   +GA    L  A  V      LP GLR+   +RPL+VP G+P
Sbjct: 325 PEGEEGALERSLLAAEGVEPASFDLPGGLRMEGERRPLRVPLGDP 369

>CSK_CHICK (P41239) Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase)|
          Length = 450

 Score = 32.3 bits (72), Expect = 1.5
 Identities = 30/98 (30%), Positives = 42/98 (42%), Gaps = 3/98 (3%)
 Frame = -2

Query: 515 GLDNVLMSWGHDDYMYLVAKENKTTL---PSAGLFIIRYHSFYPLHKHGAYTHLMNEEDK 345
           G+   LM W H      + +E    L   P  GLF++R  + YP    G YT  ++ E K
Sbjct: 74  GIKLSLMPWFHGK----ITREQAERLLYPPETGLFLVRESTNYP----GDYTLCVSCEGK 125

Query: 344 ENLKWLHVFNKYDLYSKSSVRIDVEKVKPYYMSLIEKY 231
                  V +   +YS S + ID E      M L+E Y
Sbjct: 126 -------VEHYRIIYSSSKLSIDEEVYFENLMQLVEHY 156

>SPB1_CRYNE (Q5KM86) AdoMet-dependent rRNA methyltransferase SPB1 (EC 2.1.1.-)|
           (2'-O-ribose RNA methyltransferase)
           (S-adenosyl-L-methionine-dependent methyltransferase)
          Length = 908

 Score = 32.3 bits (72), Expect = 1.5
 Identities = 20/64 (31%), Positives = 29/64 (45%)
 Frame = -2

Query: 413 RYHSFYPLHKHGAYTHLMNEEDKENLKWLHVFNKYDLYSKSSVRIDVEKVKPYYMSLIEK 234
           R   FY L K   Y        +   K +H+  KYDL SK+   ID+      ++ + EK
Sbjct: 12  RLDKFYRLAKEQGY------RARSAFKLVHLNRKYDLLSKARCCIDLCAAPGGWLQVAEK 65

Query: 233 YFPE 222
           Y P+
Sbjct: 66  YMPK 69

>TOP1_RICPR (Q9ZDK2) DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I)|
           (Omega-protein) (Relaxing enzyme) (Untwisting enzyme)
           (Swivelase)
          Length = 776

 Score = 30.4 bits (67), Expect = 5.5
 Identities = 21/64 (32%), Positives = 33/64 (51%)
 Frame = -2

Query: 518 CGLDNVLMSWGHDDYMYLVAKENKTTLPSAGLFIIRYHSFYPLHKHGAYTHLMNEEDKEN 339
           C ++NV+M    D  +  +A ENK  L  A   II +  FY +     Y   +++ED+E+
Sbjct: 388 CQMENVIM----DLVIANLASENKEYLAKANGSIIAFDGFYKV-----YRESLDDEDEED 438

Query: 338 LKWL 327
            K L
Sbjct: 439 NKML 442

>RIN2_HUMAN (Q8WYP3) Ras and Rab interactor 2 (Ras interaction/interference|
           protein 2) (Ras inhibitor JC265) (Ras association domain
           family 4)
          Length = 895

 Score = 30.0 bits (66), Expect = 7.2
 Identities = 16/45 (35%), Positives = 28/45 (62%), Gaps = 2/45 (4%)
 Frame = -2

Query: 347 KENLKWLHVFNKYDL--YSKSSVRIDVEKVKPYYMSLIEKYFPEK 219
           KENL+ +   N  +L  ++ +   +DVEK+K  +M++ + Y PEK
Sbjct: 625 KENLQLVRQRNPQELGVFAPTPDFVDVEKIKVKFMTMQKMYSPEK 669

>GRPE_THEMA (Q9WZV4) Protein grpE (HSP-70 cofactor)|
          Length = 172

 Score = 30.0 bits (66), Expect = 7.2
 Identities = 15/41 (36%), Positives = 24/41 (58%), Gaps = 1/41 (2%)
 Frame = -2

Query: 374 YTHLMNEEDKENLKWLHVFNKYDLYSKSSV-RIDVEKVKPY 255
           Y  L+N  +KE L  +HV  K+D +   +V R++ E V+ Y
Sbjct: 88  YKKLLNVLEKEGLTKIHVGEKFDPFEHEAVERVETEDVEEY 128


  Database: uniprot_sprot.fasta
    Posted date:  May 25, 2006  5:36 PM
  Number of letters in database: 80,573,946
  Number of sequences in database:  219,361
  
Lambda     K      H
   0.318    0.135    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 100,652,848
Number of Sequences: 219361
Number of extensions: 2131864
Number of successful extensions: 5780
Number of sequences better than 10.0: 17
Number of HSP's better than 10.0 without gapping: 5564
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5774
length of database: 80,573,946
effective HSP length: 109
effective length of database: 56,663,597
effective search space used: 7139613222
frameshift window, decay const: 50,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)