ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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| Clone Name | rbasd27j05 |
|---|---|
| Clone Library Name | barley_pub |
>IDHP_MEDSA (Q40345) Isocitrate dehydrogenase [NADP], chloroplast precursor (EC| 1.1.1.42) (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific ICDH) (IDP) (Fragment) Length = 433 Score = 331 bits (849), Expect = 1e-90 Identities = 160/176 (90%), Positives = 169/176 (96%) Frame = -2 Query: 751 EIYEAGWKSKYEAAGIWYEHRLIDDMVAYALKSEGGYVWACKNYDGDVQSDFLAQGFGSL 572 E+YEAGWKSKYEAAGIWYEHRLIDDMVAYALKSEGGYVWACKNYDGDVQSDFLAQGFGSL Sbjct: 252 EVYEAGWKSKYEAAGIWYEHRLIDDMVAYALKSEGGYVWACKNYDGDVQSDFLAQGFGSL 311 Query: 571 GLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDD 392 GLMTSVL+CPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDD Sbjct: 312 GLMTSVLVCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDD 371 Query: 391 NARLLEFAQKLEEACVGTVESGKMTKDLALLVHGSSKVTRSDYLNTEEFIDAVAAE 224 NA LL+F +KLE AC+G VESGKMTKDLAL++HG SK++R YLNTEEFIDAVAAE Sbjct: 372 NATLLDFTEKLEAACIGVVESGKMTKDLALILHG-SKLSREHYLNTEEFIDAVAAE 426
>IDHC_SOYBN (Q06197) Isocitrate dehydrogenase [NADP] (EC 1.1.1.42)| (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific ICDH) (IDP) Length = 413 Score = 327 bits (839), Expect = 2e-89 Identities = 157/176 (89%), Positives = 169/176 (96%) Frame = -2 Query: 751 EIYEAGWKSKYEAAGIWYEHRLIDDMVAYALKSEGGYVWACKNYDGDVQSDFLAQGFGSL 572 E+YEA WKSK+EAAGIWYEHRLIDDMVAYALKSEGGYVWACKNYDGDVQSDFLAQGFGSL Sbjct: 232 EVYEASWKSKFEAAGIWYEHRLIDDMVAYALKSEGGYVWACKNYDGDVQSDFLAQGFGSL 291 Query: 571 GLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDD 392 GLMTSVL+CPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDD Sbjct: 292 GLMTSVLVCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDD 351 Query: 391 NARLLEFAQKLEEACVGTVESGKMTKDLALLVHGSSKVTRSDYLNTEEFIDAVAAE 224 NA+LL+F +KLE AC+G VE+GKMTKDLAL++HG SK++R YLNTEEFIDAVAAE Sbjct: 352 NAKLLDFTEKLEAACIGVVEAGKMTKDLALILHG-SKLSREHYLNTEEFIDAVAAE 406
>IDHC_TOBAC (P50218) Isocitrate dehydrogenase [NADP] (EC 1.1.1.42)| (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific ICDH) (IDP) Length = 415 Score = 319 bits (817), Expect = 7e-87 Identities = 153/176 (86%), Positives = 164/176 (93%) Frame = -2 Query: 751 EIYEAGWKSKYEAAGIWYEHRLIDDMVAYALKSEGGYVWACKNYDGDVQSDFLAQGFGSL 572 E+YEA WKSKYE AGIWYEHRLIDDM AYALKSEGGYVWACKNYDGDVQSDFLAQGFGSL Sbjct: 231 EVYEANWKSKYEEAGIWYEHRLIDDMAAYALKSEGGYVWACKNYDGDVQSDFLAQGFGSL 290 Query: 571 GLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDD 392 GLMTSVL+CPDGKTIEAEAAHGTVTRH+RVHQKGGETSTNSIASIFAWTRGLAHRA LD+ Sbjct: 291 GLMTSVLVCPDGKTIEAEAAHGTVTRHYRVHQKGGETSTNSIASIFAWTRGLAHRATLDN 350 Query: 391 NARLLEFAQKLEEACVGTVESGKMTKDLALLVHGSSKVTRSDYLNTEEFIDAVAAE 224 N RLL+F +KLE AC+G VESGKMTKDLAL++HG SK++R YLNTEEFIDAVA E Sbjct: 351 NERLLDFTEKLEAACIGAVESGKMTKDLALIIHG-SKLSRDHYLNTEEFIDAVADE 405
>IDHC_SOLTU (P50217) Isocitrate dehydrogenase [NADP] (EC 1.1.1.42)| (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific ICDH) (IDP) Length = 416 Score = 318 bits (814), Expect = 1e-86 Identities = 152/176 (86%), Positives = 163/176 (92%) Frame = -2 Query: 751 EIYEAGWKSKYEAAGIWYEHRLIDDMVAYALKSEGGYVWACKNYDGDVQSDFLAQGFGSL 572 E+YEA WKSKYE AGIWYEHRLIDDMVAYALKSEGGYVWACKNYDGDVQSDFLAQGFGSL Sbjct: 231 EVYEANWKSKYEEAGIWYEHRLIDDMVAYALKSEGGYVWACKNYDGDVQSDFLAQGFGSL 290 Query: 571 GLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDD 392 GLMTSVL+CPDGKTIEAEAAHGTVTRH+RVHQKGGETSTNSIASIFAWTRGLAHRA LD+ Sbjct: 291 GLMTSVLVCPDGKTIEAEAAHGTVTRHYRVHQKGGETSTNSIASIFAWTRGLAHRATLDN 350 Query: 391 NARLLEFAQKLEEACVGTVESGKMTKDLALLVHGSSKVTRSDYLNTEEFIDAVAAE 224 N RLL+F +KLE AC+G VESGKMTKDLAL++ SK++R YLNTEEFIDAVA E Sbjct: 351 NERLLDFTEKLEAACIGAVESGKMTKDLALIIIHGSKLSREHYLNTEEFIDAVADE 406
>IDHC_RAT (P41562) Isocitrate dehydrogenase [NADP] cytoplasmic (EC 1.1.1.42)| (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific ICDH) (IDP) Length = 414 Score = 265 bits (676), Expect = 1e-70 Identities = 125/171 (73%), Positives = 146/171 (85%) Frame = -2 Query: 751 EIYEAGWKSKYEAAGIWYEHRLIDDMVAYALKSEGGYVWACKNYDGDVQSDFLAQGFGSL 572 EIY+ +KSK+EA IWYEHRLIDDMVA A+KSEGG++WACKNYDGDVQSD +AQG+GSL Sbjct: 229 EIYDKQYKSKFEAQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSL 288 Query: 571 GLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDD 392 G+MTSVL+CPDGKT+EAEAAHGTVTRH+R++QKG ETSTN IASIFAW+RGLAHRAKLD+ Sbjct: 289 GMMTSVLICPDGKTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWSRGLAHRAKLDN 348 Query: 391 NARLLEFAQKLEEACVGTVESGKMTKDLALLVHGSSKVTRSDYLNTEEFID 239 N L FA LEE C+ T+E+G MTKDLA + G V RSDYLNT EF+D Sbjct: 349 NTELSFFANALEEVCIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMD 399
>IDHC_MICOH (Q9Z2K8) Isocitrate dehydrogenase [NADP] cytoplasmic (EC 1.1.1.42)| (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific ICDH) (IDP) Length = 414 Score = 265 bits (676), Expect = 1e-70 Identities = 124/171 (72%), Positives = 147/171 (85%) Frame = -2 Query: 751 EIYEAGWKSKYEAAGIWYEHRLIDDMVAYALKSEGGYVWACKNYDGDVQSDFLAQGFGSL 572 EIY+ +KS++EA IWYEHRLIDDMVA A+KSEGG++WACKNYDGDVQSD +AQG+GSL Sbjct: 229 EIYDKQYKSQFEAQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSL 288 Query: 571 GLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDD 392 G+MTSVL+CPDGKT+EAEAAHGTVTRH+R+HQKG ETSTN IASIFAW+RGLAHRA+LD+ Sbjct: 289 GMMTSVLICPDGKTVEAEAAHGTVTRHYRMHQKGQETSTNPIASIFAWSRGLAHRARLDN 348 Query: 391 NARLLEFAQKLEEACVGTVESGKMTKDLALLVHGSSKVTRSDYLNTEEFID 239 N L FA+ LEE C+ T+E+G MTKDLA + G V RSDYLNT EF+D Sbjct: 349 NTELSFFAKALEEVCIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMD 399
>IDHC_MICME (Q9Z2K9) Isocitrate dehydrogenase [NADP] cytoplasmic (EC 1.1.1.42)| (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific ICDH) (IDP) Length = 414 Score = 265 bits (676), Expect = 1e-70 Identities = 124/171 (72%), Positives = 147/171 (85%) Frame = -2 Query: 751 EIYEAGWKSKYEAAGIWYEHRLIDDMVAYALKSEGGYVWACKNYDGDVQSDFLAQGFGSL 572 EIY+ +KS++EA IWYEHRLIDDMVA A+KSEGG++WACKNYDGDVQSD +AQG+GSL Sbjct: 229 EIYDKQYKSQFEAQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSL 288 Query: 571 GLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDD 392 G+MTSVL+CPDGKT+EAEAAHGTVTRH+R+HQKG ETSTN IASIFAW+RGLAHRA+LD+ Sbjct: 289 GMMTSVLICPDGKTVEAEAAHGTVTRHYRMHQKGQETSTNPIASIFAWSRGLAHRARLDN 348 Query: 391 NARLLEFAQKLEEACVGTVESGKMTKDLALLVHGSSKVTRSDYLNTEEFID 239 N L FA+ LEE C+ T+E+G MTKDLA + G V RSDYLNT EF+D Sbjct: 349 NTELSFFAKALEEVCIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMD 399
>IDHC_HUMAN (O75874) Isocitrate dehydrogenase [NADP] cytoplasmic (EC 1.1.1.42)| (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific ICDH) (IDP) Length = 414 Score = 261 bits (666), Expect = 2e-69 Identities = 124/171 (72%), Positives = 145/171 (84%) Frame = -2 Query: 751 EIYEAGWKSKYEAAGIWYEHRLIDDMVAYALKSEGGYVWACKNYDGDVQSDFLAQGFGSL 572 EIY+ +KS++EA IWYEHRLIDDMVA A+KSEGG++WACKNYDGDVQSD +AQG+GSL Sbjct: 229 EIYDKQYKSQFEAQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSL 288 Query: 571 GLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDD 392 G+MTSVL+CPDGKT+EAEAAHGTVTRH+R++QKG ETSTN IASIFAWTRGLAHRAKLD+ Sbjct: 289 GMMTSVLVCPDGKTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDN 348 Query: 391 NARLLEFAQKLEEACVGTVESGKMTKDLALLVHGSSKVTRSDYLNTEEFID 239 N L FA LEE + T+E+G MTKDLA + G V RSDYLNT EF+D Sbjct: 349 NKELAFFANALEEVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMD 399
>IDHC_MOUSE (O88844) Isocitrate dehydrogenase [NADP] cytoplasmic (EC 1.1.1.42)| (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific ICDH) (IDP) Length = 414 Score = 258 bits (659), Expect = 1e-68 Identities = 122/171 (71%), Positives = 146/171 (85%) Frame = -2 Query: 751 EIYEAGWKSKYEAAGIWYEHRLIDDMVAYALKSEGGYVWACKNYDGDVQSDFLAQGFGSL 572 EIY+ +KS++EA I YEHRLIDDMVA A+KSEGG++WACKNYDGDVQSD +AQG+GSL Sbjct: 229 EIYDKKYKSQFEAQNICYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSL 288 Query: 571 GLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDD 392 G+MTSVL+CPDGKT+EAEAAHGTVTRH+R++QKG ETSTN IASIFAW+RGLAHRAKLD+ Sbjct: 289 GMMTSVLICPDGKTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWSRGLAHRAKLDN 348 Query: 391 NARLLEFAQKLEEACVGTVESGKMTKDLALLVHGSSKVTRSDYLNTEEFID 239 N L FA+ LE+ C+ T+E+G MTKDLA + G V RSDYLNT EF+D Sbjct: 349 NTELSFFAKALEDVCIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMD 399
>IDHP_PIG (P33198) Isocitrate dehydrogenase [NADP], mitochondrial precursor| (EC 1.1.1.42) (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific ICDH) (IDP) (ICD-M) (Fragment) Length = 421 Score = 254 bits (649), Expect = 2e-67 Identities = 124/174 (71%), Positives = 141/174 (81%), Gaps = 1/174 (0%) Frame = -2 Query: 751 EIYEAGWKSKYEAAGIWYEHRLIDDMVAYALKSEGGYVWACKNYDGDVQSDFLAQGFGSL 572 EI+E +K+ ++ IWYEHRLIDDMVA LKS GG+VWACKNYDGDVQSD LAQGFGSL Sbjct: 237 EIFEKHYKTDFDKYKIWYEHRLIDDMVAQVLKSSGGFVWACKNYDGDVQSDILAQGFGSL 296 Query: 571 GLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDD 392 GLMTSVL+CPDGKTIEAEAAHGTVTRH+R HQKG TSTN IASIFAWTRGL HR KLD Sbjct: 297 GLMTSVLVCPDGKTIEAEAAHGTVTRHYREHQKGRPTSTNPIASIFAWTRGLEHRGKLDG 356 Query: 391 NARLLEFAQKLEEACVGTVESGKMTKDLALLVHGSSKVTRSD-YLNTEEFIDAV 233 N L+ FAQ LE+ CV TVESG MTKDLA +HG S V ++ +LNT +F+D + Sbjct: 357 NQDLIRFAQTLEKVCVETVESGAMTKDLAGCIHGLSNVKLNEHFLNTSDFLDTI 410
>IDHP_BOVIN (Q04467) Isocitrate dehydrogenase [NADP], mitochondrial precursor| (EC 1.1.1.42) (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific ICDH) (IDP) (ICD-M) Length = 452 Score = 253 bits (646), Expect = 4e-67 Identities = 123/173 (71%), Positives = 141/173 (81%), Gaps = 1/173 (0%) Frame = -2 Query: 748 IYEAGWKSKYEAAGIWYEHRLIDDMVAYALKSEGGYVWACKNYDGDVQSDFLAQGFGSLG 569 I+E +K++++ IWYEHRLIDDMVA LKS GG+VWACKNYDGDVQSD LAQGFGSLG Sbjct: 269 IFEKHYKTEFDKHKIWYEHRLIDDMVAQVLKSSGGFVWACKNYDGDVQSDILAQGFGSLG 328 Query: 568 LMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDN 389 LMTSVL+CPDGKTIEAEAAHGTVTRH+R HQKG TSTN IASIFAWTRGL HR KLD N Sbjct: 329 LMTSVLVCPDGKTIEAEAAHGTVTRHYREHQKGRPTSTNPIASIFAWTRGLEHRGKLDGN 388 Query: 388 ARLLEFAQKLEEACVGTVESGKMTKDLALLVHGSSKVTRSD-YLNTEEFIDAV 233 L+ FAQ LE+ CV TVESG MTKDLA +HG S V ++ +LNT +F+D + Sbjct: 389 QDLIRFAQTLEKVCVETVESGAMTKDLAGCIHGLSNVKLNEHFLNTSDFLDTI 441
>IDHP_HUMAN (P48735) Isocitrate dehydrogenase [NADP], mitochondrial precursor| (EC 1.1.1.42) (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific ICDH) (IDP) (ICD-M) Length = 452 Score = 253 bits (645), Expect = 6e-67 Identities = 123/174 (70%), Positives = 141/174 (81%), Gaps = 1/174 (0%) Frame = -2 Query: 751 EIYEAGWKSKYEAAGIWYEHRLIDDMVAYALKSEGGYVWACKNYDGDVQSDFLAQGFGSL 572 EI++ +K+ ++ IWYEHRLIDDMVA LKS GG+VWACKNYDGDVQSD LAQGFGSL Sbjct: 268 EIFDKHYKTDFDKNKIWYEHRLIDDMVAQVLKSSGGFVWACKNYDGDVQSDILAQGFGSL 327 Query: 571 GLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDD 392 GLMTSVL+CPDGKTIEAEAAHGTVTRH+R HQKG TSTN IASIFAWTRGL HR KLD Sbjct: 328 GLMTSVLVCPDGKTIEAEAAHGTVTRHYREHQKGRPTSTNPIASIFAWTRGLEHRGKLDG 387 Query: 391 NARLLEFAQKLEEACVGTVESGKMTKDLALLVHGSSKVTRSD-YLNTEEFIDAV 233 N L+ FAQ LE+ CV TVESG MTKDLA +HG S V ++ +LNT +F+D + Sbjct: 388 NQDLIRFAQMLEKVCVETVESGAMTKDLAGCIHGLSNVKLNEHFLNTTDFLDTI 441
>IDH_MYCTU (P65097) Isocitrate dehydrogenase [NADP] (EC 1.1.1.42)| (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific ICDH) (IDP) Length = 409 Score = 241 bits (614), Expect = 2e-63 Identities = 118/173 (68%), Positives = 139/173 (80%) Frame = -2 Query: 748 IYEAGWKSKYEAAGIWYEHRLIDDMVAYALKSEGGYVWACKNYDGDVQSDFLAQGFGSLG 569 +YE +K+++EAAG+ YEHRLIDDMVA LK EGGYVWACKNYDGDVQSD +AQG+GSLG Sbjct: 233 VYEEEFKAQFEAAGLTYEHRLIDDMVAACLKWEGGYVWACKNYDGDVQSDTVAQGYGSLG 292 Query: 568 LMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDN 389 LMTSVLM DGKT+EAEAAHGTVTRH+R +Q G TSTN IASIFAWTRGL HR KLD Sbjct: 293 LMTSVLMTADGKTVEAEAAHGTVTRHYRQYQAGKPTSTNPIASIFAWTRGLQHRGKLDGT 352 Query: 388 ARLLEFAQKLEEACVGTVESGKMTKDLALLVHGSSKVTRSDYLNTEEFIDAVA 230 +++FA KLE + TVESGKMTKDLA+L+ D+LN+EEF+DA+A Sbjct: 353 PEVIDFAHKLESVVIATVESGKMTKDLAILIG-----PEQDWLNSEEFLDAIA 400
>IDH_MYCBO (P65098) Isocitrate dehydrogenase [NADP] (EC 1.1.1.42)| (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific ICDH) (IDP) Length = 409 Score = 241 bits (614), Expect = 2e-63 Identities = 118/173 (68%), Positives = 139/173 (80%) Frame = -2 Query: 748 IYEAGWKSKYEAAGIWYEHRLIDDMVAYALKSEGGYVWACKNYDGDVQSDFLAQGFGSLG 569 +YE +K+++EAAG+ YEHRLIDDMVA LK EGGYVWACKNYDGDVQSD +AQG+GSLG Sbjct: 233 VYEEEFKAQFEAAGLTYEHRLIDDMVAACLKWEGGYVWACKNYDGDVQSDTVAQGYGSLG 292 Query: 568 LMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDN 389 LMTSVLM DGKT+EAEAAHGTVTRH+R +Q G TSTN IASIFAWTRGL HR KLD Sbjct: 293 LMTSVLMTADGKTVEAEAAHGTVTRHYRQYQAGKPTSTNPIASIFAWTRGLQHRGKLDGT 352 Query: 388 ARLLEFAQKLEEACVGTVESGKMTKDLALLVHGSSKVTRSDYLNTEEFIDAVA 230 +++FA KLE + TVESGKMTKDLA+L+ D+LN+EEF+DA+A Sbjct: 353 PEVIDFAHKLESVVIATVESGKMTKDLAILIG-----PEQDWLNSEEFLDAIA 400
>IDHP_MOUSE (P54071) Isocitrate dehydrogenase [NADP], mitochondrial precursor| (EC 1.1.1.42) (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific ICDH) (IDP) (ICD-M) Length = 523 Score = 237 bits (605), Expect = 3e-62 Identities = 118/174 (67%), Positives = 136/174 (78%), Gaps = 1/174 (0%) Frame = -2 Query: 751 EIYEAGWKSKYEAAGIWYEHRLIDDMVAYALKSEGGYVWACKNYDGDVQSDFLAQGFGSL 572 EI++ +K+ ++ IWYEHRLIDDMVA LKS GG+VWACKNYDGDVQSD LA FGSL Sbjct: 340 EIFDKHYKTDFDRNKIWYEHRLIDDMVAQVLKSSGGFVWACKNYDGDVQSDILASRFGSL 399 Query: 571 GLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDD 392 GLMTSVL+CPDGKTIEAEAAHGTVTRH+R HQKG TST IASIFAWTRGL HR KLD Sbjct: 400 GLMTSVLVCPDGKTIEAEAAHGTVTRHYREHQKGRPTSTKGIASIFAWTRGLEHRGKLDG 459 Query: 391 NARLLEFAQKLEEACVGTVESGKMTKDLALLVHGSSKVTRSD-YLNTEEFIDAV 233 N L+ FAQ E+ CV TVE G MTKDLA +HG S V ++ +LNT +F+D + Sbjct: 460 NQDLIRFAQTREKVCVQTVE-GAMTKDLAGCIHGLSNVKLNEHFLNTTDFLDTI 512
>IDHC_YEAST (P41939) Isocitrate dehydrogenase [NADP] cytoplasmic (EC 1.1.1.42)| (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific ICDH) (IDP) Length = 412 Score = 230 bits (586), Expect = 4e-60 Identities = 118/173 (68%), Positives = 137/173 (79%), Gaps = 1/173 (0%) Frame = -2 Query: 748 IYEAGWKSKYEAAGIWYEHRLIDDMVAYALKSEGGYVWACKNYDGDVQSDFLAQGFGSLG 569 +Y +K K+E+ GIWYEHRLIDDMVA LKS+GGY+ A KNYDGDV+SD +AQGFGSLG Sbjct: 230 MYARSYKEKFESLGIWYEHRLIDDMVAQMLKSKGGYIIAMKNYDGDVESDIVAQGFGSLG 289 Query: 568 LMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDN 389 LMTSVL+ PDGKT E+EAAHGTVTRHFR HQ+G ETSTNSIASIFAWTRG+ R KLD+ Sbjct: 290 LMTSVLITPDGKTFESEAAHGTVTRHFRQHQQGKETSTNSIASIFAWTRGIIQRGKLDNT 349 Query: 388 ARLLEFAQKLEEACVGTV-ESGKMTKDLALLVHGSSKVTRSDYLNTEEFIDAV 233 +++F Q LE A V TV E G MTKDLAL++ K RS Y+ TEEFIDAV Sbjct: 350 PDVVKFGQILESATVNTVQEDGIMTKDLALIL---GKSERSAYVTTEEFIDAV 399
>IDH1_CANTR (O13285) Isocitrate dehydrogenase [NADP], mitochondrial precursor| (EC 1.1.1.42) (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific ICDH) (IDP) (CtIDP1) Length = 430 Score = 229 bits (584), Expect = 7e-60 Identities = 116/175 (66%), Positives = 138/175 (78%), Gaps = 1/175 (0%) Frame = -2 Query: 751 EIYEAGWKSKYEAAGIWYEHRLIDDMVAYALKSEGGYVWACKNYDGDVQSDFLAQGFGSL 572 +IYE + +++E G+WYEHRLIDDMVA +KS+GG+V A KNYDGDVQSD +AQGFGSL Sbjct: 254 QIYEQDYAAEFEKQGLWYEHRLIDDMVAQMIKSKGGFVMALKNYDGDVQSDIVAQGFGSL 313 Query: 571 GLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDD 392 GLMTS LM PDGK EAEAAHGTVTRH+R HQ+G ETSTNSIASIFAWTRGLA R KLD+ Sbjct: 314 GLMTSALMTPDGKAYEAEAAHGTVTRHYRQHQQGKETSTNSIASIFAWTRGLAQRGKLDE 373 Query: 391 NARLLEFAQKLEEACVGTVESGK-MTKDLALLVHGSSKVTRSDYLNTEEFIDAVA 230 +++FA KLE+A + TVE + MTKDLAL + K RS Y+ T EF+DAVA Sbjct: 374 TPDVVDFASKLEQATIDTVEVDRIMTKDLALAM---GKTDRSAYVTTTEFLDAVA 425
>IDHP_SCHPO (O14254) Probable isocitrate dehydrogenase [NADP], mitochondrial| precursor (EC 1.1.1.42) (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific ICDH) (IDP) Length = 418 Score = 229 bits (584), Expect = 7e-60 Identities = 112/176 (63%), Positives = 138/176 (78%) Frame = -2 Query: 751 EIYEAGWKSKYEAAGIWYEHRLIDDMVAYALKSEGGYVWACKNYDGDVQSDFLAQGFGSL 572 E+YE+ +K K+E G+WY+HRLIDDMVA A+KS GG+VWACKNYDGDV SD +AQ +GSL Sbjct: 239 EVYESDYKQKFEELGLWYQHRLIDDMVAQAIKSNGGFVWACKNYDGDVMSDVVAQAYGSL 298 Query: 571 GLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDD 392 GLMTSVL+ P+G+T E+EAAHGTV RH+ + KG +TSTNSIASIFAWTRGLAHR +LD Sbjct: 299 GLMTSVLIHPNGRTFESEAAHGTVQRHYMQYLKGKKTSTNSIASIFAWTRGLAHRGRLDG 358 Query: 391 NARLLEFAQKLEEACVGTVESGKMTKDLALLVHGSSKVTRSDYLNTEEFIDAVAAE 224 N RL++FA LE ACV VE G MTKDL LL + + Y++T EF+DAV +E Sbjct: 359 NERLVKFANALEHACVRCVEKGIMTKDLYLL-----SKSPNGYVDTFEFLDAVKSE 409
>IDH_SPHYA (P50215) Isocitrate dehydrogenase [NADP] (EC 1.1.1.42)| (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific ICDH) (IDP) Length = 406 Score = 226 bits (575), Expect = 8e-59 Identities = 110/173 (63%), Positives = 136/173 (78%) Frame = -2 Query: 751 EIYEAGWKSKYEAAGIWYEHRLIDDMVAYALKSEGGYVWACKNYDGDVQSDFLAQGFGSL 572 E+++A + K++AAGI YEHRLIDDMVA ALK G +VWACKNYDGDVQSD +AQGFGSL Sbjct: 227 EVFDAEFADKFKAAGIVYEHRLIDDMVASALKWSGKFVWACKNYDGDVQSDTVAQGFGSL 286 Query: 571 GLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDD 392 GLMTSVL+ PDGKT+EAEAAHGTVTRH+R HQ+G TSTN IASIFAWT+GL+ R K DD Sbjct: 287 GLMTSVLLSPDGKTVEAEAAHGTVTRHYRQHQQGKATSTNPIASIFAWTQGLSFRGKFDD 346 Query: 391 NARLLEFAQKLEEACVGTVESGKMTKDLALLVHGSSKVTRSDYLNTEEFIDAV 233 +++FA+ LE+ C+ TVE G MTKDLALL+ ++ TE+F +A+ Sbjct: 347 TPDVVKFAETLEQVCIKTVEGGAMTKDLALLIGPDQA-----WMTTEQFFEAI 394
>IDH2_CANTR (O13294) Isocitrate dehydrogenase [NADP] peroxisomal (EC 1.1.1.42)| (Oxalosuccinate decarboxylase) (IDH) (PS-NADP-IDH) (CtIDP2) Length = 410 Score = 225 bits (574), Expect = 1e-58 Identities = 114/174 (65%), Positives = 135/174 (77%), Gaps = 1/174 (0%) Frame = -2 Query: 748 IYEAGWKSKYEAAGIWYEHRLIDDMVAYALKSEGGYVWACKNYDGDVQSDFLAQGFGSLG 569 +Y + +K+K + GIWYEHRLIDDMVA LKS+GGY+ A KNYDGDVQSD +AQGFGSLG Sbjct: 231 LYASKYKTKMDELGIWYEHRLIDDMVAQMLKSKGGYIIAMKNYDGDVQSDIVAQGFGSLG 290 Query: 568 LMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDN 389 LMTSVL+ PDGK E+EAAHGTVTRH+R HQ+G ETSTNSIASI+AWTRGL R KLDD Sbjct: 291 LMTSVLVTPDGKAFESEAAHGTVTRHYRQHQQGKETSTNSIASIYAWTRGLIQRGKLDDT 350 Query: 388 ARLLEFAQKLEEACVGTVESGK-MTKDLALLVHGSSKVTRSDYLNTEEFIDAVA 230 +++FA++LE+A + TV MTKDLAL K RS Y+ TEEFID VA Sbjct: 351 PEVVKFAEELEKAVIETVSKDNIMTKDLALT---QGKTDRSSYVTTEEFIDGVA 401
>IDHP_YEAST (P21954) Isocitrate dehydrogenase [NADP], mitochondrial precursor| (EC 1.1.1.42) (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific ICDH) (IDP) Length = 428 Score = 221 bits (562), Expect = 2e-57 Identities = 114/174 (65%), Positives = 136/174 (78%), Gaps = 1/174 (0%) Frame = -2 Query: 751 EIYEAGWKSKYEAAGIWYEHRLIDDMVAYALKSEGGYVWACKNYDGDVQSDFLAQGFGSL 572 E+YEA +KSK+E GI YEHRLIDDMVA +KS+GG++ A KNYDGDVQSD +AQGFGSL Sbjct: 246 EVYEAQYKSKFEQLGIHYEHRLIDDMVAQMIKSKGGFIMALKNYDGDVQSDIVAQGFGSL 305 Query: 571 GLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDD 392 GLMTS+L+ PDGKT E+EAAHGTVTRH+R +QKG ETSTNSIASIFAW+RGL R +LD+ Sbjct: 306 GLMTSILVTPDGKTFESEAAHGTVTRHYRKYQKGEETSTNSIASIFAWSRGLLKRGELDN 365 Query: 391 NARLLEFAQKLEEACVGTV-ESGKMTKDLALLVHGSSKVTRSDYLNTEEFIDAV 233 L +FA LE A + TV + G MTKDLAL + RS Y+ TEEF+DAV Sbjct: 366 TPALCKFANILESATLNTVQQDGIMTKDLALACGNNE---RSAYVTTEEFLDAV 416
>IDHH_YEAST (P53982) Isocitrate dehydrogenase [NADP] (EC 1.1.1.42)| (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific ICDH) (IDP) Length = 420 Score = 219 bits (558), Expect = 7e-57 Identities = 111/174 (63%), Positives = 136/174 (78%), Gaps = 1/174 (0%) Frame = -2 Query: 748 IYEAGWKSKYEAAGIWYEHRLIDDMVAYALKSEGGYVWACKNYDGDVQSDFLAQGFGSLG 569 +++ +K K++A I YEHRLIDDMVA LKS+GG++ A KNYDGDVQSD +AQGFGSLG Sbjct: 230 LFDKEYKEKFQALKITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLG 289 Query: 568 LMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDN 389 LMTS+L+ PDGKT E+EAAHGTVTRHFR HQ+G ETSTNSIASIFAWTR + R KLD+ Sbjct: 290 LMTSILITPDGKTFESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNT 349 Query: 388 ARLLEFAQKLEEACVGTVE-SGKMTKDLALLVHGSSKVTRSDYLNTEEFIDAVA 230 +++F LE+A + TV+ GKMTKDLAL++ K RS Y+ TEEFID VA Sbjct: 350 DDVIKFGNLLEKATLDTVQVGGKMTKDLALML---GKTNRSSYVTTEEFIDEVA 400
>IDHP_ASPNG (P79089) Isocitrate dehydrogenase [NADP], mitochondrial precursor| (EC 1.1.1.42) (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific ICDH) (IDP) Length = 498 Score = 210 bits (535), Expect = 3e-54 Identities = 106/174 (60%), Positives = 130/174 (74%), Gaps = 1/174 (0%) Frame = -2 Query: 751 EIYEAGWKSKYEAAGIWYEHRLIDDMVAYALKSEGGYVWACKNYDGDVQSDFLAQGFGSL 572 EIYE+ ++ +EA +WYEHRLIDDMVA +KSEGG+V A KNYDGDVQSD +AQGFGSL Sbjct: 316 EIYESTYQKDFEAKNLWYEHRLIDDMVAQMIKSEGGFVMALKNYDGDVQSDIVAQGFGSL 375 Query: 571 GLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDD 392 GLMTS L+ P G+ E+EAAHGTVTRH+R HQKG ETSTN IASIFAWTRGL R KLD+ Sbjct: 376 GLMTSTLVTPTGEAFESEAAHGTVTRHYREHQKGRETSTNPIASIFAWTRGLIQRGKLDE 435 Query: 391 NARLLEFAQKLEEACVGTV-ESGKMTKDLALLVHGSSKVTRSDYLNTEEFIDAV 233 ++ FA++LE AC+ V + G MTKDLAL + R ++ T E++ AV Sbjct: 436 TPDVVTFAEELERACIEVVNDEGIMTKDLAL---ACGRKEREAWVTTREYMAAV 486
>LEU3_PELUB (Q4FP17) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 368 Score = 44.7 bits (104), Expect = 3e-04 Identities = 48/169 (28%), Positives = 69/169 (40%), Gaps = 9/169 (5%) Frame = -2 Query: 748 IYEAG--WKSKY------EAAGIWYEHRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDF 596 + EAG WK + E + H L D+ LK+ + V N GD+ SD Sbjct: 199 VMEAGQLWKEEVQELHDKEYKDVELSHMLADNCAMQLLKNPKQFDVIVTDNLFGDMLSDQ 258 Query: 595 LAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGL 416 + GSLGL+ S + K E A + + H G+ N IASI ++ L Sbjct: 259 ASMLTGSLGLLPSASLGAKNKDGEMRAMYEPI--HGSAPDIAGKEIANPIASILSFAMAL 316 Query: 415 AHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDLALLVHGSSKVTRS 269 + LD A LE+A + G TKD +L G +V+ S Sbjct: 317 RYSLDLDSE------ADALEKAVQDVLNDGLRTKD--ILSQGKKEVSTS 357
>LEU3_CAMJR (Q5HS77) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 358 Score = 43.5 bits (101), Expect = 7e-04 Identities = 44/157 (28%), Positives = 64/157 (40%), Gaps = 2/157 (1%) Frame = -2 Query: 697 EHRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTI-E 524 E+ +D+ +K+ + V C N GD+ SD LA GSLGL++S + G + E Sbjct: 216 EYMYVDNAAMQIVKNPSIFDVMLCSNLFGDILSDELAAINGSLGLLSSASLNDKGFGLYE 275 Query: 523 AEAAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACV 344 H + N IA I + L + K + + AQ +E A Sbjct: 276 PAGGSAPDIAHLNI--------ANPIAQILSAALMLKYSFKEE------QAAQDIENAIS 321 Query: 343 GTVESGKMTKDLALLVHGSSKVTRSDYLNTEEFIDAV 233 + GKMTKDL YLNT+E D + Sbjct: 322 LALAQGKMTKDL----------NAKSYLNTDEMGDCI 348
>LEU3_CAMJE (Q9PLW0) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 358 Score = 43.5 bits (101), Expect = 7e-04 Identities = 44/157 (28%), Positives = 64/157 (40%), Gaps = 2/157 (1%) Frame = -2 Query: 697 EHRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTI-E 524 E+ +D+ +K+ + V C N GD+ SD LA GSLGL++S + G + E Sbjct: 216 EYMYVDNAAMQIVKNPSIFDVMLCSNLFGDILSDELAAINGSLGLLSSASLNDKGFGLYE 275 Query: 523 AEAAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACV 344 H + N IA I + L + K + + AQ +E A Sbjct: 276 PAGGSAPDIAHLNI--------ANPIAQILSAALMLKYSFKEE------QAAQDIENAIS 321 Query: 343 GTVESGKMTKDLALLVHGSSKVTRSDYLNTEEFIDAV 233 + GKMTKDL YLNT+E D + Sbjct: 322 LALAQGKMTKDL----------NAKSYLNTDEMGDCI 348
>LEU3_BACME (P41019) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 367 Score = 42.4 bits (98), Expect = 0.002 Identities = 40/159 (25%), Positives = 69/159 (43%), Gaps = 2/159 (1%) Frame = -2 Query: 697 EHRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEA 521 EH L+D +++ + V +N GD+ SD + GSLG++ S + DG ++ Sbjct: 215 EHMLVDSAAMQLIRNPKYFDVVVTENMFGDILSDEASMLTGSLGMLPSASLTADGPSL-Y 273 Query: 520 EAAHGTVTRHFRVHQKGGETSTNSI-ASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACV 344 E HG+ G+ N I A+I + L H L+ A + +E+A Sbjct: 274 EPVHGSAP------DIAGQNKANPIAAAILSAAMLLRHSFGLEKEAAV------IEQAVE 321 Query: 343 GTVESGKMTKDLALLVHGSSKVTRSDYLNTEEFIDAVAA 227 + +G T DLA + YL T++ ++ + A Sbjct: 322 SVLHAGHRTADLA---------DGNHYLGTDKMVEVITA 351
>LEU3_RHIME (Q92KY8) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 370 Score = 41.6 bits (96), Expect = 0.003 Identities = 50/171 (29%), Positives = 74/171 (43%), Gaps = 2/171 (1%) Frame = -2 Query: 730 KSKYEAAGIWYEHRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSV 554 K+KY + + EH L D ++ + V N GD+ SD A GSLG++ S Sbjct: 212 KAKY--SDVQLEHMLADAGGMQLVRQPKQFDVIVTDNLFGDMLSDVAAMLTGSLGMLPSA 269 Query: 553 -LMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLL 377 L PD KT + +A + V H G N IA I ++ L + + L+ Sbjct: 270 SLGAPDAKTGKRKALYEPV--HGSAPDIAGTGVANPIAMIASFAMCLRY------SFNLV 321 Query: 376 EFAQKLEEACVGTVESGKMTKDLALLVHGSSKVTRSDYLNTEEFIDAVAAE 224 + A LE+A ++ G T D ++ G KV T E DA+ AE Sbjct: 322 KEADDLEKAIANVLDQGIRTGD--IMAEGCRKV------GTAEMGDAILAE 364
>LEU3_AGRT5 (P24404) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 370 Score = 41.6 bits (96), Expect = 0.003 Identities = 42/135 (31%), Positives = 60/135 (44%), Gaps = 1/135 (0%) Frame = -2 Query: 625 NYDGDVQSDFLAQGFGSLGLMTSV-LMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNS 449 N GD+ SD A GSLG++ S L PD KT + +A + V H G++ N Sbjct: 246 NLFGDMLSDVAAMLTGSLGMLPSASLGAPDAKTGKRKAMYEPV--HGSAPDIAGKSIANP 303 Query: 448 IASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDLALLVHGSSKVTRS 269 IA I ++ L + + D A KLE A ++ G T D ++ G +V Sbjct: 304 IAMIASFAMCLRYSFNMVDE------ATKLEAAIANVLDKGIRTAD--IMADGCRQV--- 352 Query: 268 DYLNTEEFIDAVAAE 224 T + DAV AE Sbjct: 353 ---GTSDMGDAVLAE 364
>LEU3_NEIMB (Q9JZI9) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 356 Score = 41.6 bits (96), Expect = 0.003 Identities = 39/148 (26%), Positives = 67/148 (45%), Gaps = 6/148 (4%) Frame = -2 Query: 733 WKSKYEAAGIWY-----EHRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSL 572 W+ +E G Y H +D+ +++ + V A N GD+ SD + GS+ Sbjct: 201 WREIFEEIGKEYPDVELSHMYVDNAAMQLVRAPKQFDVIATGNIFGDILSDEASMLTGSI 260 Query: 571 GLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDD 392 G++ S + +GK + E +HG+ G+ N +A+I + L R L+D Sbjct: 261 GMLPSASLDENGKGL-YEPSHGSAP------DIAGQNKANPLATILSLAMLL--RYSLND 311 Query: 391 NARLLEFAQKLEEACVGTVESGKMTKDL 308 AR AQ++E A ++ G T D+ Sbjct: 312 EAR----AQQVENAVQKVLQQGLRTSDI 335
>LEU3_BACLD (Q65GI9) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 370 Score = 40.8 bits (94), Expect = 0.005 Identities = 37/132 (28%), Positives = 59/132 (44%), Gaps = 1/132 (0%) Frame = -2 Query: 697 EHRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEA 521 EH L+D+ + + G + + +N GD+ SD + GSLG++ S + G + Sbjct: 219 EHMLVDNAAMQLIYAPGQFDIIVTENMFGDILSDEASMLTGSLGMLPSASLSSSGLHLY- 277 Query: 520 EAAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVG 341 E HG+ G+ N +A+I L+ L + L AQ +E A Sbjct: 278 EPVHGSAP------DIAGQNIANPLAAI------LSAAMMLRTSFGLEAEAQAVEHAVDQ 325 Query: 340 TVESGKMTKDLA 305 + +GK TKDLA Sbjct: 326 VLRAGKRTKDLA 337
>LEU3_SHEON (Q8E9N3) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 364 Score = 40.4 bits (93), Expect = 0.006 Identities = 39/131 (29%), Positives = 56/131 (42%), Gaps = 1/131 (0%) Frame = -2 Query: 697 EHRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEA 521 EH ID+ L+ + V C N GD+ SD +A GS+GL++S M G + Sbjct: 220 EHIYIDNATMQLLRRPDEFDVMLCSNLFGDILSDEIAMLTGSMGLLSSASMNSTGFGL-F 278 Query: 520 EAAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVG 341 E A G+ G+ N IA I + L H K + E A +E A Sbjct: 279 EPAGGSAP------DIAGKGIANPIAQILSAALMLRHSLKQE------EAASAIERAVTK 326 Query: 340 TVESGKMTKDL 308 + SG +T +L Sbjct: 327 ALNSGYLTGEL 337
>LEU3_NEIMA (Q9JU79) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 356 Score = 40.4 bits (93), Expect = 0.006 Identities = 38/148 (25%), Positives = 67/148 (45%), Gaps = 6/148 (4%) Frame = -2 Query: 733 WKSKYEAAGIWY-----EHRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSL 572 W+ +E G Y H +D+ +++ + V A N GD+ SD + GS+ Sbjct: 201 WREIFEEIGKEYPDVELSHMYVDNAAMQLVRAPKQFDVIATGNIFGDILSDEASMLTGSI 260 Query: 571 GLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDD 392 G++ S + +GK + E +HG+ G+ N +A++ + L R L+D Sbjct: 261 GMLPSASLDENGKGL-YEPSHGSAP------DIAGQNKANPLATVLSLAMLL--RYSLND 311 Query: 391 NARLLEFAQKLEEACVGTVESGKMTKDL 308 AR AQ++E A ++ G T D+ Sbjct: 312 EAR----AQQVENAVQKVLQQGLRTGDI 335
>IDH3A_RAT (Q99NA5) Isocitrate dehydrogenase [NAD] subunit alpha,| mitochondrial precursor (EC 1.1.1.41) (Isocitric dehydrogenase) (NAD(+)-specific ICDH) Length = 366 Score = 40.4 bits (93), Expect = 0.006 Identities = 42/127 (33%), Positives = 57/127 (44%), Gaps = 1/127 (0%) Frame = -2 Query: 625 NYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNSI 446 N GD+ SD A G LG+ S + +G I E+ HGT G+ N Sbjct: 253 NLYGDILSDLCAGLIGGLGVTQSGNIGANGVAI-FESVHGTAP------DIAGKDMANPT 305 Query: 445 ASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGK-MTKDLALLVHGSSKVTRS 269 A + + L H L + A K+E AC T++ GK +TKDL G+SK S Sbjct: 306 ALLLSAVMMLRHMG-------LFDHAAKIEAACFATIKDGKSLTKDLG----GNSKC--S 352 Query: 268 DYLNTEE 248 D+ TEE Sbjct: 353 DF--TEE 357
>IDH3A_BOVIN (P41563) Isocitrate dehydrogenase [NAD] subunit alpha,| mitochondrial precursor (EC 1.1.1.41) (Isocitric dehydrogenase) (NAD(+)-specific ICDH) (Isocitrate dehydrogenase subunits 3/4) Length = 366 Score = 40.4 bits (93), Expect = 0.006 Identities = 42/127 (33%), Positives = 57/127 (44%), Gaps = 1/127 (0%) Frame = -2 Query: 625 NYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNSI 446 N GD+ SD A G LG+ S + +G I E+ HGT G+ N Sbjct: 253 NLYGDILSDLCAGLIGGLGVTPSGNIGANGVAI-FESVHGTAP------DIAGKDMANPT 305 Query: 445 ASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGK-MTKDLALLVHGSSKVTRS 269 A + + L H L + A K+E AC T++ GK +TKDL G+SK S Sbjct: 306 ALLLSAVMMLRHMG-------LFDHAAKIETACFATIKDGKSLTKDLG----GNSKC--S 352 Query: 268 DYLNTEE 248 D+ TEE Sbjct: 353 DF--TEE 357
>LEU3_BUCUE (Q9EVH5) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 364 Score = 40.0 bits (92), Expect = 0.008 Identities = 40/156 (25%), Positives = 65/156 (41%), Gaps = 1/156 (0%) Frame = -2 Query: 694 HRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAE 518 H ID+ + +K + V C N GD+ SD A GS+G++ S + + E Sbjct: 223 HLYIDNAIMQIIKDPSQFDVILCSNLFGDIVSDECAAITGSIGMLPSASLNEKNFGL-YE 281 Query: 517 AAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGT 338 A G+ G+ N IA I + + + H L + A K++E+ V Sbjct: 282 PAGGSAP------DIAGKNIANPIAQILSVSMLVRH------GMNLKKIADKIDESVVSV 329 Query: 337 VESGKMTKDLALLVHGSSKVTRSDYLNTEEFIDAVA 230 ++ G T D++ H +YL T E D +A Sbjct: 330 LKQGYRTADISNNSH--------NYLKTSEMGDIIA 357
>LEU3_NEIG1 (Q5F8T6) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 356 Score = 40.0 bits (92), Expect = 0.008 Identities = 38/148 (25%), Positives = 67/148 (45%), Gaps = 6/148 (4%) Frame = -2 Query: 733 WKSKYEAAGIWY-----EHRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSL 572 W+ +E G Y H +D+ +++ + V A N GD+ SD + GS+ Sbjct: 201 WREIFEEIGKQYPDVELSHMYVDNAAMQLVRAPKQFDVIATGNIFGDILSDEASMLTGSI 260 Query: 571 GLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDD 392 G++ S + +GK + E +HG+ G+ N +A+I + L R L+D Sbjct: 261 GMLPSASLDENGKGL-YEPSHGSAP------DIAGQNKANPLATILSLAMLL--RYSLND 311 Query: 391 NARLLEFAQKLEEACVGTVESGKMTKDL 308 AR AQ++E + ++ G T D+ Sbjct: 312 EAR----AQQVENSVQKVLQQGLRTGDI 335
>IDH3A_MOUSE (Q9D6R2) Isocitrate dehydrogenase [NAD] subunit alpha,| mitochondrial precursor (EC 1.1.1.41) (Isocitric dehydrogenase) (NAD(+)-specific ICDH) Length = 366 Score = 39.7 bits (91), Expect = 0.010 Identities = 34/107 (31%), Positives = 47/107 (43%), Gaps = 1/107 (0%) Frame = -2 Query: 625 NYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNSI 446 N GD+ SD A G LG+ S + +G I E+ HGT G+ N Sbjct: 253 NLYGDILSDLCAGLIGGLGVTPSGNIGANGVAI-FESVHGTAP------DIAGKDMANPT 305 Query: 445 ASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGK-MTKDL 308 A + + L H L + A K+E AC T++ GK +TKDL Sbjct: 306 ALLLSAVMMLRHMG-------LFDHAAKIEAACFATIKDGKSLTKDL 345
>LEU3_PHOPR (Q6LV25) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 362 Score = 39.7 bits (91), Expect = 0.010 Identities = 43/157 (27%), Positives = 68/157 (43%), Gaps = 1/157 (0%) Frame = -2 Query: 694 HRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAE 518 H ID+ +K + V C N GD+ SD A GS+G++ S + + K E Sbjct: 223 HMYIDNATMQLIKDPSQFDVMLCSNIFGDIISDECAMITGSMGMLPSASLNQE-KFGMYE 281 Query: 517 AAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGT 338 A G+ G+ N +A I + L R LD+ + A+ +E+A Sbjct: 282 PAGGSAP------DIAGKNIANPVAQIL--SAALMLRYSLDEE----KAARAIEQAVSQA 329 Query: 337 VESGKMTKDLALLVHGSSKVTRSDYLNTEEFIDAVAA 227 +E+G++T DLA + L+T E D +AA Sbjct: 330 LEAGELTADLA---------GKGAALSTSEMGDKIAA 357
>LEU3_COLP3 (Q47WG3) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 362 Score = 39.3 bits (90), Expect = 0.013 Identities = 40/148 (27%), Positives = 62/148 (41%), Gaps = 6/148 (4%) Frame = -2 Query: 733 WKSKYEAAGIWY-----EHRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSL 572 W+ E + Y EH +D+ ++ + V C N GD+ SD A GS+ Sbjct: 202 WRQVVEEVAVEYPDVELEHLYVDNAAMQLVRDPNQFDVMLCPNLFGDILSDICAMITGSM 261 Query: 571 GLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDD 392 GL+ S + DG + E A G+ G N IA I + L R L+ Sbjct: 262 GLLPSASLNSDGFGM-YEPAGGSAP------DIAGLGVANPIAQIL--SAALMLRYSLNQ 312 Query: 391 NARLLEFAQKLEEACVGTVESGKMTKDL 308 A A+ +E+A +++G +T DL Sbjct: 313 GAA----AKAIEDAVSNALDNGVLTADL 336
>LEU3_BACSU (P05645) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 365 Score = 38.9 bits (89), Expect = 0.017 Identities = 44/159 (27%), Positives = 69/159 (43%), Gaps = 1/159 (0%) Frame = -2 Query: 697 EHRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEA 521 EH L+D+ + + + V +N GD+ SD + GSLG++ S + G + Sbjct: 219 EHMLVDNAAMQLIYAPNQFDVVVTENMFGDILSDEASMLTGSLGMLPSASLSSSGLHL-F 277 Query: 520 EAAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVG 341 E HG+ G+ N A+I L+ L + L E A+ +E+A Sbjct: 278 EPVHGSAP------DIAGKGMANPFAAI------LSAAMLLRTSFGLEEEAKAVEDAVNK 325 Query: 340 TVESGKMTKDLALLVHGSSKVTRSDYLNTEEFIDAVAAE 224 + SGK T+DLA S+ S TEE A+ +E Sbjct: 326 VLASGKRTRDLA-----RSEEFSSTQAITEEVKAAIMSE 359
>LEU3_BUCUA (Q9EVG6) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 363 Score = 38.9 bits (89), Expect = 0.017 Identities = 38/157 (24%), Positives = 67/157 (42%), Gaps = 1/157 (0%) Frame = -2 Query: 694 HRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAE 518 H ID+ +K + V C N GD+ SD A GS+G++ S + + K E Sbjct: 223 HLYIDNATMQIIKDPNQFDVLLCSNLFGDIISDECAMITGSIGMLPSASL-NEKKFGLYE 281 Query: 517 AAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGT 338 A G+ G+ N IA I + + + + + L + A K++++ + Sbjct: 282 PAGGSAP------DIEGKNIANPIAQILSLSMLVRY------SMNLKKIADKIDQSVISV 329 Query: 337 VESGKMTKDLALLVHGSSKVTRSDYLNTEEFIDAVAA 227 ++ G T D++ +DYL T E D +A+ Sbjct: 330 LKKGYRTADIS---------NNNDYLKTNEMGDVIAS 357
>LEU3_HAEIN (P43860) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 358 Score = 38.9 bits (89), Expect = 0.017 Identities = 39/132 (29%), Positives = 56/132 (42%), Gaps = 1/132 (0%) Frame = -2 Query: 697 EHRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEA 521 EH ID+ +KS + V C N GD+ SD A GS+G++ S + +G + Sbjct: 221 EHIYIDNATMQLIKSPESFDVLLCSNIFGDIISDEAAMITGSMGMLPSASLNEEGFGL-Y 279 Query: 520 EAAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVG 341 E A G+ G+ N IA I + L + L+ E A +E A Sbjct: 280 EPAGGSAP------DIAGKGIANPIAQILSAAMMLRYSFNLN------EAADAIESAVQK 327 Query: 340 TVESGKMTKDLA 305 + SG T DLA Sbjct: 328 VLASGHRTADLA 339
>IDH3A_DROME (Q9VWH4) Probable isocitrate dehydrogenase [NAD] subunit alpha,| mitochondrial precursor (EC 1.1.1.41) (Isocitric dehydrogenase) (NAD(+)-specific ICDH) Length = 377 Score = 38.5 bits (88), Expect = 0.022 Identities = 39/135 (28%), Positives = 57/135 (42%), Gaps = 2/135 (1%) Frame = -2 Query: 706 IWYEHRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKT 530 I +E + +D + +++ G Y V N GD+ SD A G LGL S M +G Sbjct: 241 IQFEEKYLDTVCLNMVQNPGKYDVLVMPNLYGDILSDMCAGLVGGLGLTPSGNMGLNGAL 300 Query: 529 IEAEAAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEA 350 E+ HGT G+ N A + + L H L +A K+E A Sbjct: 301 F--ESVHGTAP------DIAGKDLANPTALLLSAVMMLRH-------MELNTYADKIERA 345 Query: 349 CVGTVESGK-MTKDL 308 T++ GK +T DL Sbjct: 346 AFETIKEGKYLTGDL 360
>LEU3_WOLSU (Q7M886) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 358 Score = 38.1 bits (87), Expect = 0.029 Identities = 38/148 (25%), Positives = 67/148 (45%), Gaps = 1/148 (0%) Frame = -2 Query: 694 HRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAE 518 H ID+ +++ + V N GD+ SD + GS+GL+ S + GK E Sbjct: 216 HMYIDNAAMQLIRNPKQFDVILTGNLFGDILSDEASMLSGSIGLLPSASI--GGKAALYE 273 Query: 517 AAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGT 338 HG+ G+ N IA+I + + L H + +E A +++A V T Sbjct: 274 PIHGSAP------DIAGQGIANPIATIASASMMLRH------SLGEVEAADAIDKAIVKT 321 Query: 337 VESGKMTKDLALLVHGSSKVTRSDYLNT 254 ++ G TKD+A G+ ++ +D + + Sbjct: 322 LKEGYRTKDIA--AFGAKEICTTDEMGS 347
>LEU3_RHILO (Q98E57) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 367 Score = 38.1 bits (87), Expect = 0.029 Identities = 33/107 (30%), Positives = 49/107 (45%), Gaps = 1/107 (0%) Frame = -2 Query: 625 NYDGDVQSDFLAQGFGSLGLMTSV-LMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNS 449 N GD+ SD A GS+G++ S L PD KT + +A + V H G+ N Sbjct: 246 NLFGDMLSDIAAMLTGSIGMLPSASLGAPDVKTKKRKALYEPV--HGSAPDIAGKGIANP 303 Query: 448 IASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDL 308 IA I ++ L + + D A +LE A ++ G TKD+ Sbjct: 304 IAMIASFAMCLRYSFGMVDE------ADRLEGAIAAVLDQGLRTKDI 344
>LEU3_SHIDS (Q32K21) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 363 Score = 37.7 bits (86), Expect = 0.038 Identities = 43/156 (27%), Positives = 64/156 (41%), Gaps = 1/156 (0%) Frame = -2 Query: 694 HRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAE 518 H ID+ +K + V C N GD+ SD A GS+G++ S + G + E Sbjct: 223 HMYIDNATMQLIKDPSQFDVLLCSNLFGDILSDECAMITGSMGMLPSASLNEQGFGL-YE 281 Query: 517 AAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGT 338 A G+ G+ N IA I + L + DD A +E A Sbjct: 282 PAGGSAP------DIAGKNIANPIAQILSLALLLRYSLDADD------AASAIERAINRA 329 Query: 337 VESGKMTKDLALLVHGSSKVTRSDYLNTEEFIDAVA 230 +E G T+DLA G++ V +T+E D +A Sbjct: 330 LEEGIRTRDLA---RGAAAV------STDEMGDIIA 356
>LEU3_BUCUO (Q9EVI1) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 364 Score = 37.4 bits (85), Expect = 0.050 Identities = 38/156 (24%), Positives = 67/156 (42%), Gaps = 1/156 (0%) Frame = -2 Query: 694 HRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAE 518 H ID+ + +K+ + V C N GD+ SD A GS+G++ S + + K E Sbjct: 224 HLYIDNAIMQIIKNPNQFDVLLCPNLFGDIISDECAIITGSIGMLPSASL-NEKKFGLYE 282 Query: 517 AAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGT 338 A G+ G+ N IA I + + + + L D A K++++ + Sbjct: 283 PAGGSAP------DIAGKNIANPIAQILSLSMLVRYGMNLKD------IADKIDKSVLSV 330 Query: 337 VESGKMTKDLALLVHGSSKVTRSDYLNTEEFIDAVA 230 ++ G T D++ ++YL T E D +A Sbjct: 331 LKKGYRTADIS---------NNNNYLKTNEMGDVIA 357
>LEU3_SALTY (P37412) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 363 Score = 37.4 bits (85), Expect = 0.050 Identities = 45/156 (28%), Positives = 66/156 (42%), Gaps = 1/156 (0%) Frame = -2 Query: 694 HRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAE 518 H ID+ +K + V C N GD+ SD A GS+G++ S + G + E Sbjct: 223 HMYIDNATMQLIKDPSQFDVLLCSNLFGDILSDECAMITGSMGMLPSASLNEQGFGL-YE 281 Query: 517 AAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGT 338 A G+ G+ N IA I + L R LD N + A +E+A Sbjct: 282 PAGGSAP------DIAGKNIANPIAQIL--SLALLLRYSLDAN----DAATAIEQAINRA 329 Query: 337 VESGKMTKDLALLVHGSSKVTRSDYLNTEEFIDAVA 230 +E G T DLA G++ V +T+E D +A Sbjct: 330 LEEGVRTGDLA---RGAAAV------STDEMGDIIA 356
>LEU3_SALPA (Q5PDG2) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 363 Score = 37.4 bits (85), Expect = 0.050 Identities = 45/156 (28%), Positives = 66/156 (42%), Gaps = 1/156 (0%) Frame = -2 Query: 694 HRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAE 518 H ID+ +K + V C N GD+ SD A GS+G++ S + G + E Sbjct: 223 HMYIDNATMQLIKDPSQFDVLLCSNLFGDILSDECAMITGSMGMLPSASLNEQGFGL-YE 281 Query: 517 AAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGT 338 A G+ G+ N IA I + L R LD N + A +E+A Sbjct: 282 PAGGSAP------DIAGKNIANPIAQIL--SLALLLRYSLDAN----DAATAIEQAINRA 329 Query: 337 VESGKMTKDLALLVHGSSKVTRSDYLNTEEFIDAVA 230 +E G T DLA G++ V +T+E D +A Sbjct: 330 LEEGVRTGDLA---RGAAAV------STDEMGDIIA 356
>LEU3_SALCH (Q57TE7) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 363 Score = 37.4 bits (85), Expect = 0.050 Identities = 45/156 (28%), Positives = 66/156 (42%), Gaps = 1/156 (0%) Frame = -2 Query: 694 HRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAE 518 H ID+ +K + V C N GD+ SD A GS+G++ S + G + E Sbjct: 223 HMYIDNATMQLIKDPSQFDVLLCSNLFGDILSDECAMITGSMGMLPSASLNEQGFGL-YE 281 Query: 517 AAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGT 338 A G+ G+ N IA I + L R LD N + A +E+A Sbjct: 282 PAGGSAP------DIAGKNIANPIAQIL--SLALLLRYSLDAN----DAATAIEQAINRA 329 Query: 337 VESGKMTKDLALLVHGSSKVTRSDYLNTEEFIDAVA 230 +E G T DLA G++ V +T+E D +A Sbjct: 330 LEEGVRTGDLA---RGAAAV------STDEMGDIIA 356
>LEU3_BACHD (Q9K8E9) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 363 Score = 37.4 bits (85), Expect = 0.050 Identities = 33/132 (25%), Positives = 58/132 (43%), Gaps = 1/132 (0%) Frame = -2 Query: 697 EHRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEA 521 EH L+D+ ++ + V +N GD+ SD + GSLG++ S + DG + Sbjct: 218 EHMLVDNAAMQLIRRPKQFDVLVTENLFGDILSDEASMVTGSLGMLPSASLTSDGPGL-Y 276 Query: 520 EAAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVG 341 E HG+ G+ N +A+I + L + L + A+ +E+A Sbjct: 277 EPIHGSAP------DIAGKGVANPLATIASCAMMLKYSFGLHEEAK------TIEDAIEA 324 Query: 340 TVESGKMTKDLA 305 ++ G T D+A Sbjct: 325 VLKQGYRTADIA 336
>LEU3_BACCZ (Q63DX7) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 354 Score = 37.4 bits (85), Expect = 0.050 Identities = 39/148 (26%), Positives = 64/148 (43%), Gaps = 6/148 (4%) Frame = -2 Query: 733 WKSKYEAAGIWY-----EHRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSL 572 W++ E + Y EH L+D +++ G + V +N GD+ SD + GSL Sbjct: 193 WRTVTEEVALRYPDVELEHILVDAAAMELIRNPGRFDVIVTENLFGDILSDEASVLAGSL 252 Query: 571 GLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDD 392 G++ S G ++ E HG+ G+ N IA + R +A L Sbjct: 253 GMLPSASHAEKGPSL-YEPIHGSAP------DIAGKNKANPIAMM----RSVA--MMLGQ 299 Query: 391 NARLLEFAQKLEEACVGTVESGKMTKDL 308 + L +EEA ++SGK T+D+ Sbjct: 300 SFGLTREGCAIEEAISAVLKSGKCTEDI 327
>LEU3_BACCR (Q81G11) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 354 Score = 37.4 bits (85), Expect = 0.050 Identities = 39/148 (26%), Positives = 63/148 (42%), Gaps = 6/148 (4%) Frame = -2 Query: 733 WKSKYEAAGIWY-----EHRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSL 572 W++ E + Y EH L+D +++ G + V +N GD+ SD + GSL Sbjct: 193 WRTVTEEVALRYPNVEVEHILVDAAAMELIRNPGRFDVIVTENLFGDILSDEASVLAGSL 252 Query: 571 GLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDD 392 G++ S G ++ E HG+ G+ N IA + R +A L Sbjct: 253 GMLPSASHAEKGPSL-YEPIHGSAP------DIAGKNKANPIAMM----RSVA--MMLGQ 299 Query: 391 NARLLEFAQKLEEACVGTVESGKMTKDL 308 + L +EEA ++SGK T D+ Sbjct: 300 SFGLTREGYAIEEAVSAVLKSGKCTADI 327
>LEU3_PASMU (Q9CJN6) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 359 Score = 37.0 bits (84), Expect = 0.065 Identities = 43/157 (27%), Positives = 63/157 (40%), Gaps = 1/157 (0%) Frame = -2 Query: 697 EHRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEA 521 +H ID+ +K + V C N GD+ SD A GS+G++ S + G + Sbjct: 221 DHIYIDNATMQLIKQPEFFDVLLCSNIFGDIISDECAMITGSMGMLPSASLNEKGFGL-Y 279 Query: 520 EAAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVG 341 E A G+ G+ N IA I + L H L+D A +E A K Sbjct: 280 EPAGGSAP------DIAGKGIANPIAQILSAAMMLRHSFNLNDAATAIENAVK------N 327 Query: 340 TVESGKMTKDLALLVHGSSKVTRSDYLNTEEFIDAVA 230 + G T DLA S L+T++ D +A Sbjct: 328 VLAEGHRTADLA---------DESQPLSTKQMGDLIA 355
>LEU3_LEPIN (P24015) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 358 Score = 37.0 bits (84), Expect = 0.065 Identities = 34/141 (24%), Positives = 62/141 (43%), Gaps = 1/141 (0%) Frame = -2 Query: 724 KYEAAGIWYEHRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLM 548 K E + + H +D+ + + + V C+N GD+ SD + GS+G++ S + Sbjct: 211 KKEFSDVQLNHLYVDNAAMQLIVNPKQFDVVLCENMFGDILSDEASIITGSIGMLPSASL 270 Query: 547 CPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFA 368 G + E + G+ G+ N IA + + L + +++ A Sbjct: 271 SESGFGLY-EPSGGSAP------DIAGKGVANPIAQVLSAALMLRYSFSMEEEAN----- 318 Query: 367 QKLEEACVGTVESGKMTKDLA 305 K+E A T+ SGK T+D+A Sbjct: 319 -KIETAVRKTIASGKRTRDIA 338
>LEU3_LEPIC (Q72RH7) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 358 Score = 37.0 bits (84), Expect = 0.065 Identities = 34/141 (24%), Positives = 62/141 (43%), Gaps = 1/141 (0%) Frame = -2 Query: 724 KYEAAGIWYEHRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLM 548 K E + + H +D+ + + + V C+N GD+ SD + GS+G++ S + Sbjct: 211 KKEFSDVQLNHLYVDNAAMQLIVNPKQFDVVLCENMFGDILSDEASIITGSIGMLPSASL 270 Query: 547 CPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFA 368 G + E + G+ G+ N IA + + L + +++ A Sbjct: 271 SESGFGLY-EPSGGSAP------DIAGKGVANPIAQVLSAALMLRYSFSMEEEAN----- 318 Query: 367 QKLEEACVGTVESGKMTKDLA 305 K+E A T+ SGK T+D+A Sbjct: 319 -KIETAVRKTIASGKRTRDIA 338
>LEU3_YERPE (Q8ZIG9) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 363 Score = 36.6 bits (83), Expect = 0.085 Identities = 38/131 (29%), Positives = 52/131 (39%), Gaps = 1/131 (0%) Frame = -2 Query: 694 HRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAE 518 H ID+ +K + V C N GD+ SD A GS+G++ S + G + E Sbjct: 223 HMYIDNATMQLIKDPSQFDVLLCSNLFGDILSDECAMITGSMGMLPSASLNEQGFGL-YE 281 Query: 517 AAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGT 338 A G+ G+ N IA I + T L DD A +E A Sbjct: 282 PAGGSAP------DIAGKNIANPIAQILSLTLLLRFSLGKDD------AADAIERAINQA 329 Query: 337 VESGKMTKDLA 305 +E G T DLA Sbjct: 330 LEQGYRTADLA 340
>LEU3_VIBPA (Q87SS8) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 363 Score = 36.6 bits (83), Expect = 0.085 Identities = 37/131 (28%), Positives = 56/131 (42%), Gaps = 1/131 (0%) Frame = -2 Query: 694 HRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAE 518 H ID+ +K + V C N GD+ SD A GS+G++ S + + K E Sbjct: 224 HMYIDNATMQLIKDPAQFDVMLCSNIFGDIISDECAMITGSMGMLPSASL-NESKFGLYE 282 Query: 517 AAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGT 338 A G+ G+ N +A I + L R L + A AQ +E A Sbjct: 283 PAGGSAP------DIAGKNIANPVAQIL--SAALMLRYSLGEEAA----AQDIESAVSKA 330 Query: 337 VESGKMTKDLA 305 + +G++T DLA Sbjct: 331 LSAGELTADLA 341
>LEU3_RHOPA (Q6ND82) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 370 Score = 36.6 bits (83), Expect = 0.085 Identities = 33/107 (30%), Positives = 50/107 (46%), Gaps = 1/107 (0%) Frame = -2 Query: 625 NYDGDVQSDFLAQGFGSLGLMTSVLMCP-DGKTIEAEAAHGTVTRHFRVHQKGGETSTNS 449 N GD+ SD A GSLG++ S + D KT + ++ + V H G+ N Sbjct: 246 NLFGDMLSDIAAMLTGSLGMLPSASLGEVDAKTGKRKSMYEPV--HGSAPDIAGKGMANP 303 Query: 448 IASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDL 308 +A + ++ G+A R LD A A KL+EA + G T D+ Sbjct: 304 VAMLASF--GMALRYSLDMGA----LADKLDEAIAAVLAKGLRTADI 344
>LEU3_BRUSU (Q8FVF3) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 370 Score = 36.6 bits (83), Expect = 0.085 Identities = 49/174 (28%), Positives = 75/174 (43%), Gaps = 5/174 (2%) Frame = -2 Query: 730 KSKYEAAGIWYEHRLID----DMVAYALKSEGGYVWACKNYDGDVQSDFLAQGFGSLGLM 563 + K + A + EH L D +V + + + V N GD+ SD A GSLG++ Sbjct: 210 RHKEKHADVQLEHMLADAGGMQLVRWPKQFD---VILTDNLFGDLLSDVAAMLTGSLGML 266 Query: 562 TSV-LMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNA 386 S L D KT + +A + V H G+ N IA I + L + + Sbjct: 267 PSASLGAADSKTGKRKALYEPV--HGSAPDIAGKGIANPIAMIASLAMCLRY------SF 318 Query: 385 RLLEFAQKLEEACVGTVESGKMTKDLALLVHGSSKVTRSDYLNTEEFIDAVAAE 224 L+ A +LE A G ++ G T D + G++KV T E DA+ A+ Sbjct: 319 GLVAEADRLEAAIAGVLDDGIRTAD--IWSEGNTKV------GTTEMGDAILAK 364
>LEU3_BRUME (Q8YCX4) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 370 Score = 36.6 bits (83), Expect = 0.085 Identities = 49/174 (28%), Positives = 75/174 (43%), Gaps = 5/174 (2%) Frame = -2 Query: 730 KSKYEAAGIWYEHRLID----DMVAYALKSEGGYVWACKNYDGDVQSDFLAQGFGSLGLM 563 + K + A + EH L D +V + + + V N GD+ SD A GSLG++ Sbjct: 210 RHKEKHADVQLEHMLADAGGMQLVRWPKQFD---VILTDNLFGDLLSDVAAMLTGSLGML 266 Query: 562 TSV-LMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNA 386 S L D KT + +A + V H G+ N IA I + L + + Sbjct: 267 PSASLGAADSKTGKRKALYEPV--HGSAPDIAGKGIANPIAMIASLAMCLRY------SF 318 Query: 385 RLLEFAQKLEEACVGTVESGKMTKDLALLVHGSSKVTRSDYLNTEEFIDAVAAE 224 L+ A +LE A G ++ G T D + G++KV T E DA+ A+ Sbjct: 319 GLVAEADRLEAAIAGVLDDGIRTAD--IWSEGNTKV------GTTEMGDAILAK 364
>LEU3_BACHK (Q6HLF2) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 354 Score = 36.6 bits (83), Expect = 0.085 Identities = 39/148 (26%), Positives = 63/148 (42%), Gaps = 6/148 (4%) Frame = -2 Query: 733 WKSKYEAAGIWY-----EHRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSL 572 W++ E + Y EH L+D +++ G + V +N GD+ SD + GSL Sbjct: 193 WRTVTEEVALRYPDVELEHILVDAAAMELIRNPGRFDVIVTENLFGDILSDEASVLAGSL 252 Query: 571 GLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDD 392 G++ S G ++ E HG+ G+ N IA + R +A L Sbjct: 253 GMLPSASHAEKGPSL-YEPIHGSAP------DIAGKNKANPIAMM----RSVA--MMLGQ 299 Query: 391 NARLLEFAQKLEEACVGTVESGKMTKDL 308 + L +EEA ++SGK T D+ Sbjct: 300 SFGLTREGCAIEEAISAVLKSGKCTADI 327
>LEU3_BUCTS (O31292) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 364 Score = 36.2 bits (82), Expect = 0.11 Identities = 30/101 (29%), Positives = 44/101 (43%), Gaps = 1/101 (0%) Frame = -2 Query: 730 KSKYEAAGIWYEHRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSV 554 K Y+ + EH ID+ +K+ + V C N GD+ SD A GS+GL+ S Sbjct: 211 KMAYKFPNVKLEHMYIDNATMELIKNPSSFDVILCSNLFGDIISDECAAIIGSIGLLPSA 270 Query: 553 LMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNSIASIFA 431 + G + E A G+ G+T N IA I + Sbjct: 271 SLNKSGFGL-YEPAGGSAP------NIAGKTIANPIAQILS 304
>LEU3_VIBVY (Q7MP78) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 363 Score = 36.2 bits (82), Expect = 0.11 Identities = 37/131 (28%), Positives = 56/131 (42%), Gaps = 1/131 (0%) Frame = -2 Query: 694 HRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAE 518 H ID+ +K + V C N GD+ SD A GS+G++ S + + K E Sbjct: 224 HMYIDNATMQLIKDPAQFDVMLCSNIFGDIISDECAMITGSMGMLPSASL-NESKFGLYE 282 Query: 517 AAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGT 338 A G+ G+ N +A I + L R L + A AQ +E A Sbjct: 283 PAGGSAP------DIAGKNIANPVAQIL--SAALMLRYSLGEEAA----AQDIENAVSQA 330 Query: 337 VESGKMTKDLA 305 + +G++T DLA Sbjct: 331 LAAGELTADLA 341
>LEU3_VIBVU (Q8DEE0) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 363 Score = 36.2 bits (82), Expect = 0.11 Identities = 37/131 (28%), Positives = 56/131 (42%), Gaps = 1/131 (0%) Frame = -2 Query: 694 HRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAE 518 H ID+ +K + V C N GD+ SD A GS+G++ S + + K E Sbjct: 224 HMYIDNATMQLIKDPAQFDVMLCSNIFGDIISDECAMITGSMGMLPSASL-NESKFGLYE 282 Query: 517 AAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGT 338 A G+ G+ N +A I + L R L + A AQ +E A Sbjct: 283 PAGGSAP------DIAGKNIANPVAQIL--SAALMLRYSLGEEAA----AQDIENAVSQA 330 Query: 337 VESGKMTKDLA 305 + +G++T DLA Sbjct: 331 LAAGELTADLA 341
>LEU3_VIBCH (Q9KP82) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 363 Score = 36.2 bits (82), Expect = 0.11 Identities = 37/131 (28%), Positives = 56/131 (42%), Gaps = 1/131 (0%) Frame = -2 Query: 694 HRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAE 518 H ID+ +K + V C N GD+ SD A GS+G++ S M + K E Sbjct: 224 HMYIDNATMQLIKDPAQFDVMLCSNIFGDILSDECAMITGSMGMLPSASM-NESKFGLYE 282 Query: 517 AAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGT 338 A G+ G+ N +A I + L R L + A A+ +E A Sbjct: 283 PAGGSAP------DIAGKNIANPVAQIL--SAALMLRYSLGEEAA----ARDIENAVSQA 330 Query: 337 VESGKMTKDLA 305 + +G++T DLA Sbjct: 331 LAAGELTADLA 341
>LEU3_ERWCT (Q6D0G7) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 363 Score = 36.2 bits (82), Expect = 0.11 Identities = 41/156 (26%), Positives = 62/156 (39%), Gaps = 1/156 (0%) Frame = -2 Query: 694 HRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAE 518 H ID+ +K + V C N GD+ SD A GS+G++ S + G + E Sbjct: 223 HLYIDNATMQLIKDPSQFDVMLCSNLFGDILSDECAMITGSMGMLPSASLNEQGFGL-YE 281 Query: 517 AAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGT 338 A G+ G+ N IA I + L + DD A+ +E+A Sbjct: 282 PAGGSAP------DIAGKDIANPIAQILSLALLLRYSLGADD------AAEAIEKAVNTA 329 Query: 337 VESGKMTKDLALLVHGSSKVTRSDYLNTEEFIDAVA 230 + G T DLA + S+ + T E D +A Sbjct: 330 LAEGYRTADLA---------SASNAIGTSEMGDVIA 356
>LEU3_BUCUS (Q9EVI4) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 363 Score = 36.2 bits (82), Expect = 0.11 Identities = 37/157 (23%), Positives = 66/157 (42%), Gaps = 1/157 (0%) Frame = -2 Query: 694 HRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAE 518 H ID+ +K+ + + C N GD+ SD A GS+G++ S + + K E Sbjct: 223 HLYIDNATMQIIKNPNQFDILLCSNLFGDIISDECAMITGSIGMLPSASL-NEKKFGLYE 281 Query: 517 AAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGT 338 A G+ G+ N IA I + + + + + L A K++++ + Sbjct: 282 PAGGSAP------DIEGKNIANPIAQILSVSMLVRY------SMNLKTIADKIDQSVISV 329 Query: 337 VESGKMTKDLALLVHGSSKVTRSDYLNTEEFIDAVAA 227 ++ G T D++ S YL T E D +A+ Sbjct: 330 LKKGYRTADIS---------NNSHYLKTNEMGDVIAS 357
>LEU3_CAUCR (Q9ABN3) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 350 Score = 36.2 bits (82), Expect = 0.11 Identities = 36/138 (26%), Positives = 56/138 (40%), Gaps = 1/138 (0%) Frame = -2 Query: 718 EAAGIWYEHRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCP 542 E + EH L D+ +++ + V N GD+ SD A GSLG++ S + Sbjct: 208 EYPDVQLEHILADNCAMQLVRAPKQFDVIVTDNLFGDILSDAAAMLTGSLGMLPSAALGA 267 Query: 541 DGKTIEAEAAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQK 362 GK E HG+ G+ N +A+I ++ L K E A Sbjct: 268 PGKPGLYEPIHGSAP------DIAGKGLANPLAAILSFEMALRWSLK------QTEAADA 315 Query: 361 LEEACVGTVESGKMTKDL 308 L A +++G T+DL Sbjct: 316 LLAAVKAALDNGARTRDL 333
>LEU3_SHIFL (Q83SP1) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 362 Score = 36.2 bits (82), Expect = 0.11 Identities = 43/156 (27%), Positives = 63/156 (40%), Gaps = 1/156 (0%) Frame = -2 Query: 694 HRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAE 518 H ID+ +K + V C N GD+ SD A GS+G++ S + G + E Sbjct: 222 HMYIDNATMQLIKDPSQFDVLLCSNLFGDILSDECAMITGSMGMLPSASLNEQGFGL-YE 280 Query: 517 AAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGT 338 A G+ G+ N IA I + L + DD A +E A Sbjct: 281 PAGGSAP------DIAGKNIANPIAQILSLALLLRYSLDADD------AASAIERAINRA 328 Query: 337 VESGKMTKDLALLVHGSSKVTRSDYLNTEEFIDAVA 230 +E G T DLA G++ V +T+E D +A Sbjct: 329 LEEGIRTGDLA---RGAAAV------STDEMGDIIA 355
>LEU3_HAEI8 (Q4QLS3) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 358 Score = 36.2 bits (82), Expect = 0.11 Identities = 38/132 (28%), Positives = 55/132 (41%), Gaps = 1/132 (0%) Frame = -2 Query: 697 EHRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEA 521 EH ID+ +K+ + V C N GD+ SD A GS+G++ S + G + Sbjct: 221 EHIYIDNATMQLIKAPESFDVLLCSNIFGDIISDEAAMITGSMGMLPSASLNEAGFGL-Y 279 Query: 520 EAAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVG 341 E A G+ G+ N IA I + L + L+ E A +E A Sbjct: 280 EPAGGSAP------DIAGKGIANPIAQILSAAMMLRYSFNLN------EAADAIESAVQK 327 Query: 340 TVESGKMTKDLA 305 + SG T DLA Sbjct: 328 VLASGHRTADLA 339
>LEU3_ECOL6 (Q8FL76) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 362 Score = 36.2 bits (82), Expect = 0.11 Identities = 43/156 (27%), Positives = 63/156 (40%), Gaps = 1/156 (0%) Frame = -2 Query: 694 HRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAE 518 H ID+ +K + V C N GD+ SD A GS+G++ S + G + E Sbjct: 222 HMYIDNATMQLIKDPSQFDVLLCSNLFGDILSDECAMITGSMGMLPSASLNEQGFGL-YE 280 Query: 517 AAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGT 338 A G+ G+ N IA I + L + DD A +E A Sbjct: 281 PAGGSAP------DIAGKNIANPIAQILSLALLLRYSLDADD------AASAIERAINRA 328 Query: 337 VESGKMTKDLALLVHGSSKVTRSDYLNTEEFIDAVA 230 +E G T DLA G++ V +T+E D +A Sbjct: 329 LEEGIRTGDLA---RGAAAV------STDEMGDIIA 355
>LEU3_ECO57 (Q8X9Z9) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 362 Score = 36.2 bits (82), Expect = 0.11 Identities = 43/156 (27%), Positives = 63/156 (40%), Gaps = 1/156 (0%) Frame = -2 Query: 694 HRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAE 518 H ID+ +K + V C N GD+ SD A GS+G++ S + G + E Sbjct: 222 HMYIDNATMQLIKDPSQFDVLLCSNLFGDILSDECAMITGSMGMLPSASLNEQGFGL-YE 280 Query: 517 AAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGT 338 A G+ G+ N IA I + L + DD A +E A Sbjct: 281 PAGGSAP------DIAGKNIANPIAQILSLALLLRYSLDADD------AASAIERAINRA 328 Query: 337 VESGKMTKDLALLVHGSSKVTRSDYLNTEEFIDAVA 230 +E G T DLA G++ V +T+E D +A Sbjct: 329 LEEGIRTGDLA---RGAAAV------STDEMGDIIA 355
>LEU3_PHOLL (Q7N128) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 363 Score = 35.8 bits (81), Expect = 0.15 Identities = 41/148 (27%), Positives = 61/148 (41%), Gaps = 1/148 (0%) Frame = -2 Query: 694 HRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAE 518 H ID+ +K + V C N GD+ SD A GS+G++ S + G + E Sbjct: 223 HMYIDNATMQLIKDPSQFDVMLCSNIFGDILSDECAMITGSMGMLPSASLNEKGFGL-YE 281 Query: 517 AAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGT 338 A G+ G+ N IA I + L R L N + A +E+A Sbjct: 282 PAGGSAP------DIAGKGIANPIAQIL--SAALLLRYSLGHN----DAANAIEQAVNYA 329 Query: 337 VESGKMTKDLALLVHGSSKVTRSDYLNT 254 +E G T DLA G+ K +D + + Sbjct: 330 LEQGYRTTDLA----GNGKAISTDEMGS 353
>LEU3_BUCUH (Q9EVH8) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 363 Score = 35.8 bits (81), Expect = 0.15 Identities = 40/174 (22%), Positives = 72/174 (41%), Gaps = 6/174 (3%) Frame = -2 Query: 733 WKSKYEAAGIWY-----EHRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSL 572 W+ E Y H ID+ +K+ + V C N GD+ SD A GS+ Sbjct: 205 WREVVEKVSKMYPDVHLSHLYIDNATMQIIKNPNQFDVLLCSNLFGDIISDECAVITGSI 264 Query: 571 GLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDD 392 G++ S + E A G+ G+ + N IA I + + + + KL+ Sbjct: 265 GMLPSASFNEKNFGL-YEPAGGSAP------DIAGKNTANPIAQILSLSMLVRYGMKLN- 316 Query: 391 NARLLEFAQKLEEACVGTVESGKMTKDLALLVHGSSKVTRSDYLNTEEFIDAVA 230 + A K+++A ++++G T D++ +++L T E D +A Sbjct: 317 -----KIADKIDDAVALSLKAGYRTADIS---------NDNNFLKTNEMGDVIA 356
>LEU3_BUCDN (O85071) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 363 Score = 35.8 bits (81), Expect = 0.15 Identities = 37/156 (23%), Positives = 64/156 (41%), Gaps = 1/156 (0%) Frame = -2 Query: 694 HRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAE 518 H ID++ +K + V C N GD+ SD A GS+G++ S + + E Sbjct: 223 HLYIDNVCMQIIKDPNQFDVLLCSNLFGDIISDECAMITGSIGMLPSASLNEKNFGL-YE 281 Query: 517 AAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGT 338 A G+ G+ N IA I + + + + L+ + A K++ A + Sbjct: 282 PAGGSAP------DIQGKNIANPIAQILSLSMLIRYSMNLN------KIANKIDNAVINV 329 Query: 337 VESGKMTKDLALLVHGSSKVTRSDYLNTEEFIDAVA 230 ++ G T D++ +YL T E D +A Sbjct: 330 LKKGYKTMDIS---------KDQNYLKTNEMGDVIA 356
>LEU3_SYMTH (Q67JY2) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 368 Score = 35.8 bits (81), Expect = 0.15 Identities = 38/141 (26%), Positives = 54/141 (38%), Gaps = 9/141 (6%) Frame = -2 Query: 697 EHRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLM--------C 545 EH L D+ L+ G + V N GD SD A GS+GL+ S + Sbjct: 223 EHLLADNAAMQILRRPGDFDVMLASNLFGDFLSDEAAMLTGSIGLLPSASLGAARNRFGL 282 Query: 544 PDGKTIEAEAAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQ 365 P G E HG+ G+ N +A+I L H +D AR Sbjct: 283 PKG---FYEPIHGSAP------DIAGQDRANPLAAILCGAMLLRHSLGREDAAR------ 327 Query: 364 KLEEACVGTVESGKMTKDLAL 302 +E+A +E G T D+ + Sbjct: 328 AVEQAVAAVLEEGLRTADITV 348
>LEU3_DESPS (Q6ANR1) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 357 Score = 35.8 bits (81), Expect = 0.15 Identities = 40/138 (28%), Positives = 56/138 (40%) Frame = -2 Query: 640 VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGET 461 V C N GD+ SD A GS+GL+ S + + + E A G+ G+ Sbjct: 239 VMLCGNMFGDIISDEAAMLTGSMGLLASASLNTENFGL-FEPAGGSAP------DIAGQG 291 Query: 460 STNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDLALLVHGSSK 281 N IA I + L + E A +E A T++ G T D+A Sbjct: 292 IANPIAEILSAAMMLRYSLGYG------EAADAIEAAVEKTLDRGICTADIA-------- 337 Query: 280 VTRSDYLNTEEFIDAVAA 227 V RS +NT E DA+ A Sbjct: 338 VDRSQAVNTAEMGDAIVA 355
>LEU3_VIBF1 (Q5E857) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 363 Score = 35.4 bits (80), Expect = 0.19 Identities = 36/131 (27%), Positives = 55/131 (41%), Gaps = 1/131 (0%) Frame = -2 Query: 694 HRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAE 518 H ID+ +K + V C N GD+ SD A GS+G++ S + + E Sbjct: 224 HMYIDNATMQLIKDPSQFDVMLCSNIFGDIISDECAMITGSMGMLPSASLNESNFGL-YE 282 Query: 517 AAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGT 338 A G+ G+ N +A I + L R L + E AQ +E A Sbjct: 283 PAGGSAP------DIAGKNIANPVAQIL--SAALMLRYSLGEE----EAAQSIEAAVSKA 330 Query: 337 VESGKMTKDLA 305 + +G++T DLA Sbjct: 331 LSAGELTADLA 341
>LEU3_BACAN (Q81T67) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 354 Score = 35.4 bits (80), Expect = 0.19 Identities = 39/148 (26%), Positives = 62/148 (41%), Gaps = 6/148 (4%) Frame = -2 Query: 733 WKSKYEAAGIWY-----EHRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSL 572 W+ E + Y EH L+D +++ G + V +N GD+ SD + GSL Sbjct: 193 WRIVTEEVALRYPDVELEHILVDAAAMELIRNPGRFDVIVTENLFGDILSDEASVLAGSL 252 Query: 571 GLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDD 392 G++ S G ++ E HG+ G+ N IA + R +A L Sbjct: 253 GMLPSASHAEKGPSL-YEPIHGSAP------DIAGKNKANPIAMM----RSVA--MMLGQ 299 Query: 391 NARLLEFAQKLEEACVGTVESGKMTKDL 308 + L +EEA ++SGK T D+ Sbjct: 300 SFGLTREGCAIEEAISAVLKSGKCTADI 327
>LEU3_SHISS (Q3Z5T7) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 363 Score = 35.0 bits (79), Expect = 0.25 Identities = 43/156 (27%), Positives = 63/156 (40%), Gaps = 1/156 (0%) Frame = -2 Query: 694 HRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAE 518 H ID+ +K + V C N GD+ SD A GS+G++ S + G + E Sbjct: 223 HMYIDNATMQLIKDPSQFDVLLCSNLFGDILSDECAMITGSMGMLPSASLNEQGFGL-YE 281 Query: 517 AAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGT 338 A G+ G+ N IA I + L + DD A +E A Sbjct: 282 PAGGSAP------DIAGKNIANPIAQILSLALLLRYSLDADD------AACAIERAINRA 329 Query: 337 VESGKMTKDLALLVHGSSKVTRSDYLNTEEFIDAVA 230 +E G T DLA G++ V +T+E D +A Sbjct: 330 LEEGIRTGDLA---RGAAAV------STDEMGDIIA 356
>LEU3_ZYMMO (Q5NPQ9) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 349 Score = 35.0 bits (79), Expect = 0.25 Identities = 32/130 (24%), Positives = 56/130 (43%), Gaps = 1/130 (0%) Frame = -2 Query: 694 HRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAE 518 H +D+ +++ + V N GD+ SD + GS+GL+ S + +GK + E Sbjct: 215 HMYVDNAAMQLVRAPDQFDVIVTGNLFGDILSDLASACVGSIGLLPSASLNSEGKGL-YE 273 Query: 517 AAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGT 338 HG+ G N +A+I + L + K + + A ++E+A Sbjct: 274 PIHGSAP------DIAGLGKANPLATILSGAMMLRYSLKREAD------ADRIEKAVSTA 321 Query: 337 VESGKMTKDL 308 +E G T DL Sbjct: 322 LEKGARTADL 331
>LEU3_BRAJA (Q89X19) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 370 Score = 35.0 bits (79), Expect = 0.25 Identities = 41/141 (29%), Positives = 61/141 (43%), Gaps = 2/141 (1%) Frame = -2 Query: 724 KYEAAGIWYEHRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLM 548 K E + EH+L D +K + V N GD+ SD A GSLG++ S + Sbjct: 212 KREYPDVTLEHQLADSGGMMLVKWPKQFDVIVTDNLFGDMLSDIAAMLTGSLGMLPSASL 271 Query: 547 CP-DGKTIEAEAAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEF 371 D K+ + +A + V H G+ N IA I ++ G+A R D A Sbjct: 272 GEVDVKSKKRKALYEPV--HGSAPDIAGKGLANPIAMISSF--GMALRYSFDMGA----L 323 Query: 370 AQKLEEACVGTVESGKMTKDL 308 A K++ A + SG T D+ Sbjct: 324 ADKVDAAIAAVLASGLRTADI 344
>LEU3_ECOLI (P30125) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 362 Score = 35.0 bits (79), Expect = 0.25 Identities = 43/156 (27%), Positives = 63/156 (40%), Gaps = 1/156 (0%) Frame = -2 Query: 694 HRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAE 518 H ID+ +K + V C N GD+ SD A GS+G++ S + G + E Sbjct: 222 HMYIDNATMQLIKDPSQFDVLLCSNLFGDILSDECAMITGSMGMLPSASLNEQGFGL-YE 280 Query: 517 AAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGT 338 A G+ G+ N IA I + L + DD A +E A Sbjct: 281 PAGGSAP------DIAGKNIANPIAQILSLALLLRYSLDADD------AACAIERAINRA 328 Query: 337 VESGKMTKDLALLVHGSSKVTRSDYLNTEEFIDAVA 230 +E G T DLA G++ V +T+E D +A Sbjct: 329 LEEGIRTGDLA---RGAAAV------STDEMGDIIA 355
>LEU3_GEOKA (Q5KWJ4) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 371 Score = 35.0 bits (79), Expect = 0.25 Identities = 35/132 (26%), Positives = 57/132 (43%), Gaps = 1/132 (0%) Frame = -2 Query: 697 EHRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEA 521 EH L+D+ +++ + V +N GD+ SD + GSLG++ S + G ++ Sbjct: 219 EHMLVDNAAMQLIRAPKQFDVIVTENMFGDILSDEASMLSGSLGMLPSASLSASGPSL-Y 277 Query: 520 EAAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVG 341 E HG+ G N IA+I L+ L + L A+ +E A Sbjct: 278 EPVHGSAP------DIAGMNKANPIAAI------LSAAMMLRLSFGLTAEAEAVEHAVRQ 325 Query: 340 TVESGKMTKDLA 305 ++ G T DLA Sbjct: 326 ALDQGLRTADLA 337
>LEU3_BUCUM (Q9EVG9) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 365 Score = 34.7 bits (78), Expect = 0.32 Identities = 36/156 (23%), Positives = 65/156 (41%), Gaps = 1/156 (0%) Frame = -2 Query: 694 HRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAE 518 H ID+ +K + + C N GD+ SD A GS+G++ S + + K E Sbjct: 225 HLYIDNATMQIIKDPNQFDILLCSNLFGDIVSDECAIITGSIGMLPSASL-NEKKFGLYE 283 Query: 517 AAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGT 338 A G+ G+ N IA I + + + + L + A K++++ + Sbjct: 284 PAGGSAP------DIEGKNIANPIAQILSVSMLVRY------GMNLKKIADKIDQSVISV 331 Query: 337 VESGKMTKDLALLVHGSSKVTRSDYLNTEEFIDAVA 230 ++ G T D++ ++YL T E D +A Sbjct: 332 LKKGYRTADIS---------NNNNYLKTNEMGDVIA 358
>LEU3_THET8 (Q5SIY4) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 345 Score = 34.7 bits (78), Expect = 0.32 Identities = 37/134 (27%), Positives = 56/134 (41%), Gaps = 6/134 (4%) Frame = -2 Query: 733 WKSKYEAAGIWY-----EHRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSL 572 W+ E G Y EH+ +D M + ++S + V N GD+ SD + GSL Sbjct: 195 WRKTVEEVGRGYPDVALEHQYVDAMAMHLVRSPARFDVVVTGNIFGDILSDLASVLPGSL 254 Query: 571 GLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDD 392 GL+ S + T E HG+ G+ N A+I + L H Sbjct: 255 GLLPSASL--GRGTPVFEPVHGSAP------DIAGKGIANPTAAILSAAMMLEHA----- 301 Query: 391 NARLLEFAQKLEEA 350 L+E A+K+E+A Sbjct: 302 -FGLVELARKVEDA 314
>LEU3_THET2 (P61494) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 345 Score = 34.7 bits (78), Expect = 0.32 Identities = 37/134 (27%), Positives = 56/134 (41%), Gaps = 6/134 (4%) Frame = -2 Query: 733 WKSKYEAAGIWY-----EHRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSL 572 W+ E G Y EH+ +D M + ++S + V N GD+ SD + GSL Sbjct: 195 WRKTVEEVGRGYPDVALEHQYVDAMAMHLVRSPARFDVVVTGNIFGDILSDLASVLPGSL 254 Query: 571 GLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDD 392 GL+ S + T E HG+ G+ N A+I + L H Sbjct: 255 GLLPSASL--GRGTPVFEPVHGSAP------DIAGKGLANPTAAILSAAMMLEHA----- 301 Query: 391 NARLLEFAQKLEEA 350 L+E A+K+E+A Sbjct: 302 -FGLVELARKVEDA 314
>LEU3_BUCRP (P48572) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 363 Score = 34.7 bits (78), Expect = 0.32 Identities = 38/156 (24%), Positives = 64/156 (41%), Gaps = 1/156 (0%) Frame = -2 Query: 694 HRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAE 518 H ID+ +K+ + V C N GD+ SD A GS+G++ S + K E Sbjct: 223 HLYIDNACMQIIKNPSQFDVLLCSNIFGDIISDECAMITGSIGMLPSASL-NSKKFGLYE 281 Query: 517 AAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGT 338 A G+ G+ N IA I + + + H L+ E A K++ + Sbjct: 282 PAGGSAP------DIEGKNIANPIAQILSLSMLIRHSMNLN------EIADKIDSSVYRA 329 Query: 337 VESGKMTKDLALLVHGSSKVTRSDYLNTEEFIDAVA 230 +++G T D++ +Y+ T E D +A Sbjct: 330 LKAGYRTLDIS---------DGKNYIKTNEMGDIIA 356
>LEU3_ARCFU (O29627) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 326 Score = 34.7 bits (78), Expect = 0.32 Identities = 33/106 (31%), Positives = 44/106 (41%) Frame = -2 Query: 625 NYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNSI 446 N GD+ SD A G LGL S + +T E HG F + KG T I Sbjct: 218 NMFGDIVSDLAAGLVGGLGLAPSANV--GERTAIFEPVHGAA---FDIAGKGIANPTAMI 272 Query: 445 ASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDL 308 + R + +E A+K+EEA T++ GK T DL Sbjct: 273 LTACMMLRHFGY----------VEEAKKVEEAVEKTIKEGKKTPDL 308
>LEU3_SULSO (Q9UXB2) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 336 Score = 34.7 bits (78), Expect = 0.32 Identities = 41/143 (28%), Positives = 67/143 (46%), Gaps = 2/143 (1%) Frame = -2 Query: 700 YEHRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIE 524 +E +D A ++ + V N GD+ SD +Q GSLGL S + D K++ Sbjct: 195 FEEMYVDAAAANLVRDPTRFDVIVTSNVYGDILSDEASQIAGSLGLAPSANI-GDRKSM- 252 Query: 523 AEAAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACV 344 E HG F + KG N A + + + L+ +L + + ++ LE A + Sbjct: 253 FEPVHGAA---FDIAGKG---IANPTAFLLSVSMMLSRMYELSKENKYILASKSLENAII 306 Query: 343 GTVESG-KMTKDLALLVHGSSKV 278 T +SG K+T+D V GS+K+ Sbjct: 307 ETYKSGNKLTED----VGGSAKL 325
>LEU3_GLOVI (Q7NFH4) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 362 Score = 34.7 bits (78), Expect = 0.32 Identities = 30/108 (27%), Positives = 46/108 (42%) Frame = -2 Query: 628 KNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNS 449 +N GD+ SD A GS+G++ S + G + E HG+ G+ N Sbjct: 245 ENMFGDILSDEAAMLTGSIGMLPSASLGSGGPGL-YEPVHGSAP------DIAGQDKANP 297 Query: 448 IASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDLA 305 +A + + L H + R E AQ +E A +E G T D+A Sbjct: 298 LAQVLSGAMLLRH------SLRQPEAAQAVERAVQTVLEQGYRTGDIA 339
>LEU3_METTH (O27441) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 329 Score = 34.7 bits (78), Expect = 0.32 Identities = 34/106 (32%), Positives = 43/106 (40%) Frame = -2 Query: 625 NYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNSI 446 N GD+ SD A G LGL S + K E HG+ Q G+ N Sbjct: 220 NLFGDILSDEAAGLIGGLGLAPSANI--GEKNALFEPVHGSAP------QIAGKNIANPT 271 Query: 445 ASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDL 308 A I T L H K + AQK+E+A T+ G +T DL Sbjct: 272 AMILTTTLMLKHLNKKQE-------AQKIEKALQKTLAEGLVTPDL 310
>LEU3_YERPS (Q66EM2) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 363 Score = 34.3 bits (77), Expect = 0.42 Identities = 37/131 (28%), Positives = 51/131 (38%), Gaps = 1/131 (0%) Frame = -2 Query: 694 HRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAE 518 H ID+ +K + V C N GD+ SD A GS+G++ S + G + E Sbjct: 223 HMYIDNATMQLIKDPSQFDVLLCSNLFGDILSDECAMITGSMGMLPSASLNEQGFGL-YE 281 Query: 517 AAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGT 338 A G+ G+ N IA I + L DD A +E A Sbjct: 282 PAGGSAP------DIAGKNIANPIAQILSLILLLRFSLGKDD------AADAIERAINQA 329 Query: 337 VESGKMTKDLA 305 +E G T DLA Sbjct: 330 LEQGYRTADLA 340
>LEU3_SHIBS (Q326G2) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 363 Score = 34.3 bits (77), Expect = 0.42 Identities = 43/156 (27%), Positives = 63/156 (40%), Gaps = 1/156 (0%) Frame = -2 Query: 694 HRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAE 518 H ID+ +K + V C N GD+ SD A GS+G++ S + G + E Sbjct: 223 HMYIDNATMQLIKDPSQFDVLLCSNLFGDILSDECAMITGSMGMLPSASLNEQGFGL-YE 281 Query: 517 AAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGT 338 A G+ G+ N IA I + L + DD A +E A Sbjct: 282 PAGGSAP------DITGKNIANPIAQILSLALLLRYSLDADD------AACAIERAINRA 329 Query: 337 VESGKMTKDLALLVHGSSKVTRSDYLNTEEFIDAVA 230 +E G T DLA G++ V +T+E D +A Sbjct: 330 LEEGIRTGDLA---RGAAAV------STDEMGDIIA 356
>LEU3_SALTI (Q8Z9I1) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 363 Score = 34.3 bits (77), Expect = 0.42 Identities = 42/156 (26%), Positives = 63/156 (40%), Gaps = 1/156 (0%) Frame = -2 Query: 694 HRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAE 518 H ID+ +K + V C N GD+ SD A GS+G++ S + + E Sbjct: 223 HMYIDNATMQLIKDPSQFDVLLCSNLFGDILSDECAMITGSMGMLPSASLNEQEFGL-YE 281 Query: 517 AAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGT 338 A G+ G+ N IA I + L + D E A +E+A Sbjct: 282 PAGGSAP------DIAGKNIANPIAQILSLALLLRYSLDAD------EAATAIEQAINRA 329 Query: 337 VESGKMTKDLALLVHGSSKVTRSDYLNTEEFIDAVA 230 +E G T DLA G++ V +T+E D +A Sbjct: 330 LEEGVRTSDLA---RGAAAV------STDEMGDIIA 356
>LEU3_NITWN (Q3SNU3) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 370 Score = 34.3 bits (77), Expect = 0.42 Identities = 34/107 (31%), Positives = 47/107 (43%), Gaps = 1/107 (0%) Frame = -2 Query: 625 NYDGDVQSDFLAQGFGSLGLMTSV-LMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNS 449 N GD+ SD A GSLG++ S L D KT + A + V H G+ N Sbjct: 246 NLFGDMLSDIAAMLTGSLGMLPSASLGDTDPKTEKRRALYEPV--HGSAPDIAGQGLANP 303 Query: 448 IASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDL 308 IA + ++ G+A R D + A KL+ A + G T DL Sbjct: 304 IAMLASF--GMALRYSFDRG----DLADKLDAAIAAVLAKGLRTADL 344
>LEU3_SYNY3 (P73960) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 362 Score = 34.3 bits (77), Expect = 0.42 Identities = 35/148 (23%), Positives = 60/148 (40%), Gaps = 6/148 (4%) Frame = -2 Query: 733 WKSKYEAAGIWY-----EHRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSL 572 W+ + A + Y H +D+ ++S + N GD+ SD A GS+ Sbjct: 204 WRDRVMAIAVDYPDVELSHLYVDNAAMQLVRSPRQFDTIVTGNLFGDILSDIAAMLTGSI 263 Query: 571 GLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDD 392 G++ S + DG + E HG+ G+ N +A + + + R LD Sbjct: 264 GMLPSASLGSDGPGL-FEPVHGSAP------DIAGQDKANPLAQVL--SAAMMLRYGLDQ 314 Query: 391 NARLLEFAQKLEEACVGTVESGKMTKDL 308 + A +LE+A +E G T D+ Sbjct: 315 P----QAADRLEDAVKKVLEQGYRTGDI 338
>LEU3_SOLTU (P29696) 3-isopropylmalate dehydrogenase, chloroplast precursor (EC| 1.1.1.85) (Beta-IPM dehydrogenase) (IMDH) (3-IPM-DH) Length = 357 Score = 34.3 bits (77), Expect = 0.42 Identities = 35/130 (26%), Positives = 55/130 (42%), Gaps = 1/130 (0%) Frame = -2 Query: 706 IWYEHRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKT 530 I YE +ID+ +K+ + V N GD+ SD A G LGL S + G Sbjct: 230 IKYEEVVIDNCCMMLVKNPALFDVLVMPNLYGDIISDLCAGLIGGLGLTPSCNIGEGGIA 289 Query: 529 IEAEAAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEA 350 + AEA HG+ G+ N A + + L H L + A ++++A Sbjct: 290 L-AEAVHGSAP------DIAGKNLANPTALLLSSVSMLRH-------LELHDKADRIQDA 335 Query: 349 CVGTVESGKM 320 + T+ GK+ Sbjct: 336 ILKTIAGGKV 345
>LEU3_BACC1 (Q73B99) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 354 Score = 34.3 bits (77), Expect = 0.42 Identities = 38/148 (25%), Positives = 62/148 (41%), Gaps = 6/148 (4%) Frame = -2 Query: 733 WKSKYEAAGIWY-----EHRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSL 572 W++ E + Y EH L+D +++ G + V +N GD+ SD + GSL Sbjct: 193 WRTVTEEVALRYPDVELEHILVDAAAMELIRNPGRFDVIVTENLFGDILSDEASVLAGSL 252 Query: 571 GLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDD 392 G++ S G ++ E HG+ G+ N IA + R +A L Sbjct: 253 GMLPSASHAEKGPSL-YEPIHGSAP------DIAGKNKANPIAMM----RSVA--MMLGQ 299 Query: 391 NARLLEFAQKLEEACVGTVESGKMTKDL 308 + L +EEA ++ GK T D+ Sbjct: 300 SFGLTREGCAIEEAISAVLKLGKCTADI 327
>LEU3_STAHJ (Q4L7U1) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 346 Score = 34.3 bits (77), Expect = 0.42 Identities = 37/156 (23%), Positives = 62/156 (39%), Gaps = 1/156 (0%) Frame = -2 Query: 721 YEAAGIWYEHRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMC 545 +E + H L+D + + V +N GD+ SD + GSLGL S Sbjct: 204 HEFPDVKVNHLLVDACSMQLISQPTNFDVIVTENLFGDILSDEASTIPGSLGLSPSASFS 263 Query: 544 PDGKTIEAEAAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQ 365 +G + + +H + + ++A+ F LA L ++ + A Sbjct: 264 LEGPRL-----------YEPIHGSAPDIANQNLANPFGMILSLA--MCLRESFNFEDAAS 310 Query: 364 KLEEACVGTVESGKMTKDLALLVHGSSKVTRSDYLN 257 +LE+A ++ GK TKDL + T SD N Sbjct: 311 ELEQAVYQLIKDGKTTKDL------NGHYTTSDIFN 340
>LEU3_BACSK (Q5WEN4) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 364 Score = 33.9 bits (76), Expect = 0.55 Identities = 36/139 (25%), Positives = 56/139 (40%), Gaps = 1/139 (0%) Frame = -2 Query: 718 EAAGIWYEHRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCP 542 E + H L+D+ ++ + V +N GD+ SD + GSLGL+ S M Sbjct: 211 EYPDVTLSHMLVDNAAMQLIRDPRQFDVIVTENLFGDILSDEASMITGSLGLLPSASM-N 269 Query: 541 DGKTIEAEAAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQK 362 K E HG+ G + N +A+I + L + L D A+ +E A Sbjct: 270 TSKVGLFEPVHGSAP------DIAGTGAANPLATILSAAMMLQYSFGLADEAKAIEVAVD 323 Query: 361 LEEACVGTVESGKMTKDLA 305 + G TKD+A Sbjct: 324 ------RVLAQGVRTKDIA 336
>LYS12_YEAST (P40495) Homoisocitrate dehydrogenase, mitochondrial precursor (EC| 1.1.1.87) Length = 371 Score = 33.9 bits (76), Expect = 0.55 Identities = 38/143 (26%), Positives = 59/143 (41%), Gaps = 1/143 (0%) Frame = -2 Query: 751 EIYEAGWKSKYEAAGIWYEHRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGS 575 E+YE+ K KY I Y +++D MV + + V N GD+ SD A GS Sbjct: 223 EVYESN-KDKY--GQIKYNEQIVDSMVYRLFREPQCFDVIVAPNLYGDILSDGAAALVGS 279 Query: 574 LGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLD 395 LG++ S + P+ + E HG+ + KG +I S L H Sbjct: 280 LGVVPSANVGPE--IVIGEPCHGSAP---DIAGKGIANPIATIRSTALMLEFLGHNEAAQ 334 Query: 394 DNARLLEFAQKLEEACVGTVESG 326 D + ++ L E + T + G Sbjct: 335 DIYKAVD--ANLREGSIKTPDLG 355
>LEU3_THIFE (Q56268) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 358 Score = 33.9 bits (76), Expect = 0.55 Identities = 31/131 (23%), Positives = 58/131 (44%), Gaps = 1/131 (0%) Frame = -2 Query: 694 HRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAE 518 H +D+ +++ + V N GD+ SD +Q GS+G++ S + +G+ + E Sbjct: 218 HMYVDNAAMQLIRAPAQFDVLLTGNMFGDILSDEASQLTGSIGMLPSASL-GEGRAM-YE 275 Query: 517 AAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGT 338 HG+ G+ N +A+I + L H + +AQ++E A Sbjct: 276 PIHGSAP------DIAGQDKANPLATILSVAMMLRHSLNAE------PWAQRVEAAVQRV 323 Query: 337 VESGKMTKDLA 305 ++ G T D+A Sbjct: 324 LDQGLRTADIA 334
>LEU3_STAAW (Q8NVJ0) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 348 Score = 33.9 bits (76), Expect = 0.55 Identities = 32/130 (24%), Positives = 55/130 (42%), Gaps = 1/130 (0%) Frame = -2 Query: 694 HRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAE 518 H L+D + + + + V C+N GD+ SD + GSLGL S DG + Sbjct: 213 HLLVDACSMHLITNPKQFDVIVCENLFGDILSDEASVIPGSLGLSPSASFSNDGPRL--- 269 Query: 517 AAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGT 338 + +H + + ++A+ F LA L ++ + A +LE+ Sbjct: 270 --------YEPIHGSAPDIAGKNVANPFGMILSLA--MCLRESLNQPDAADELEQHIYNM 319 Query: 337 VESGKMTKDL 308 +E G+ T DL Sbjct: 320 IEHGQTTADL 329
>LEU3_STAAS (Q6G7Q0) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 348 Score = 33.9 bits (76), Expect = 0.55 Identities = 32/130 (24%), Positives = 55/130 (42%), Gaps = 1/130 (0%) Frame = -2 Query: 694 HRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAE 518 H L+D + + + + V C+N GD+ SD + GSLGL S DG + Sbjct: 213 HLLVDACSMHLITNPKQFDVIVCENLFGDILSDEASVIPGSLGLSPSASFSNDGPRL--- 269 Query: 517 AAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGT 338 + +H + + ++A+ F LA L ++ + A +LE+ Sbjct: 270 --------YEPIHGSAPDIAGKNVANPFGMILSLA--MCLRESLNQPDAADELEQHIYNM 319 Query: 337 VESGKMTKDL 308 +E G+ T DL Sbjct: 320 IEHGQTTADL 329
>LEU3_STAAN (P65101) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 348 Score = 33.9 bits (76), Expect = 0.55 Identities = 32/130 (24%), Positives = 55/130 (42%), Gaps = 1/130 (0%) Frame = -2 Query: 694 HRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAE 518 H L+D + + + + V C+N GD+ SD + GSLGL S DG + Sbjct: 213 HLLVDACSMHLITNPKQFDVIVCENLFGDILSDEASVIPGSLGLSPSASFSNDGPRL--- 269 Query: 517 AAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGT 338 + +H + + ++A+ F LA L ++ + A +LE+ Sbjct: 270 --------YEPIHGSAPDIAGKNVANPFGMILSLA--MCLRESLNQPDAADELEQHIYNM 319 Query: 337 VESGKMTKDL 308 +E G+ T DL Sbjct: 320 IEHGQTTADL 329
>LEU3_STAAM (P65100) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 348 Score = 33.9 bits (76), Expect = 0.55 Identities = 32/130 (24%), Positives = 55/130 (42%), Gaps = 1/130 (0%) Frame = -2 Query: 694 HRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAE 518 H L+D + + + + V C+N GD+ SD + GSLGL S DG + Sbjct: 213 HLLVDACSMHLITNPKQFDVIVCENLFGDILSDEASVIPGSLGLSPSASFSNDGPRL--- 269 Query: 517 AAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGT 338 + +H + + ++A+ F LA L ++ + A +LE+ Sbjct: 270 --------YEPIHGSAPDIAGKNVANPFGMILSLA--MCLRESLNQPDAADELEQHIYNM 319 Query: 337 VESGKMTKDL 308 +E G+ T DL Sbjct: 320 IEHGQTTADL 329
>LEU3_STAAC (Q5HEE3) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 348 Score = 33.9 bits (76), Expect = 0.55 Identities = 32/130 (24%), Positives = 55/130 (42%), Gaps = 1/130 (0%) Frame = -2 Query: 694 HRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAE 518 H L+D + + + + V C+N GD+ SD + GSLGL S DG + Sbjct: 213 HLLVDACSMHLITNPKQFDVIVCENLFGDILSDEASVIPGSLGLSPSASFSNDGPRL--- 269 Query: 517 AAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGT 338 + +H + + ++A+ F LA L ++ + A +LE+ Sbjct: 270 --------YEPIHGSAPDIAGKNVANPFGMILSLA--MCLRESLNQPDAADELEQHIYSM 319 Query: 337 VESGKMTKDL 308 +E G+ T DL Sbjct: 320 IEHGQTTADL 329
>LEU3_PELCD (Q3A3B2) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 365 Score = 33.5 bits (75), Expect = 0.72 Identities = 43/158 (27%), Positives = 63/158 (39%), Gaps = 1/158 (0%) Frame = -2 Query: 694 HRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAE 518 H +D+ +K+ + V C N GD+ SD A GSLG++ S + +G E Sbjct: 223 HMYVDNAAMQLVKAPKQFDVLLCPNMFGDILSDEAAMLTGSLGMLPSASLA-EGSFGMYE 281 Query: 517 AAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGT 338 A G+ G+ N +A I + L + L D A +E K E C+ Sbjct: 282 PAGGSAP------DIAGKNIANPVAQILSAAMLLRYSCGLADAADAVE---KAVENCLA- 331 Query: 337 VESGKMTKDLALLVHGSSKVTRSDYLNTEEFIDAVAAE 224 +G T D+ G V +T DAV AE Sbjct: 332 --AGLRTGDIYQDADGEQLV------STSAMGDAVVAE 361
>LEU3_STRT2 (Q5M405) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 345 Score = 33.5 bits (75), Expect = 0.72 Identities = 35/138 (25%), Positives = 60/138 (43%), Gaps = 1/138 (0%) Frame = -2 Query: 718 EAAGIWYEHRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCP 542 E + EH+L+D + + + V +N GD+ SD + G+LG+M S Sbjct: 204 EFPDVTLEHQLVDSAAMIMITNPARFDVVVTENLFGDILSDESSVLPGTLGVMPSASHSE 263 Query: 541 DGKTIEAEAAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQK 362 +G ++ E HG+ G+ N I+ I L+ L ++ E A+ Sbjct: 264 NGPSL-YEPIHGSAP------DIAGQGIANPISMI------LSVAMMLRESFNETEGAEL 310 Query: 361 LEEACVGTVESGKMTKDL 308 +E A T+ G +T+DL Sbjct: 311 IENAVDKTLNQGILTRDL 328
>LEU3_STRT1 (Q5LZF3) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 345 Score = 33.5 bits (75), Expect = 0.72 Identities = 35/138 (25%), Positives = 60/138 (43%), Gaps = 1/138 (0%) Frame = -2 Query: 718 EAAGIWYEHRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCP 542 E + EH+L+D + + + V +N GD+ SD + G+LG+M S Sbjct: 204 EFPDVTLEHQLVDSAAMIMITNPARFDVVVTENLFGDILSDESSVLPGTLGVMPSASHSE 263 Query: 541 DGKTIEAEAAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQK 362 +G ++ E HG+ G+ N I+ I L+ L ++ E A+ Sbjct: 264 NGPSL-YEPIHGSAP------DIAGQGIANPISMI------LSVAMMLRESFNETEGAEL 310 Query: 361 LEEACVGTVESGKMTKDL 308 +E A T+ G +T+DL Sbjct: 311 IENAVDKTLNQGILTRDL 328
>LEU3_BUCUD (Q9EVE1) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 363 Score = 33.5 bits (75), Expect = 0.72 Identities = 36/156 (23%), Positives = 64/156 (41%), Gaps = 1/156 (0%) Frame = -2 Query: 694 HRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAE 518 H ID+ +K + + C N GD+ SD A GS+G++ S + + K E Sbjct: 223 HLYIDNATMQIIKDPNQFDILLCSNLFGDIISDECAIITGSIGMLPSASL-NEKKFGLYE 281 Query: 517 AAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGT 338 A G+ G+ N IA I + + + + L A K++++ + Sbjct: 282 PAGGSAP------DIEGKNIANPIAQILSVSMLVRY------GMNLKTIADKIDQSVISV 329 Query: 337 VESGKMTKDLALLVHGSSKVTRSDYLNTEEFIDAVA 230 ++ G T D++ ++YL T E D +A Sbjct: 330 LKKGYRTADIS---------NNNNYLKTNEMGDVIA 356
>LEU3_MANSM (Q65V05) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 358 Score = 33.5 bits (75), Expect = 0.72 Identities = 36/132 (27%), Positives = 55/132 (41%), Gaps = 1/132 (0%) Frame = -2 Query: 697 EHRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEA 521 E+ ID+ +K+ + V C N GD+ SD A GS+G++ S + +G + Sbjct: 221 ENMYIDNATMQLIKAPESFDVLLCSNIFGDIISDEAAMITGSMGMLPSASLNEEGFGL-Y 279 Query: 520 EAAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVG 341 E A G+ G+ N IA I + L + L+ E A +E A Sbjct: 280 EPAGGSAP------DIAGKGIANPIAQILSAAMMLRYSFNLN------EAATAIENAVQK 327 Query: 340 TVESGKMTKDLA 305 + G T DLA Sbjct: 328 VLADGHRTGDLA 339
>LEU3_NEILA (P50180) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) (Fragment) Length = 313 Score = 33.1 bits (74), Expect = 0.95 Identities = 32/122 (26%), Positives = 54/122 (44%), Gaps = 6/122 (4%) Frame = -2 Query: 733 WKSKYEAAGIWY-----EHRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSL 572 W+ +E G Y H +D+ +++ + V A N GD+ SD + GSL Sbjct: 201 WREIFEEIGKEYPDVELSHMYVDNAAMQLVRAPKQFDVIATGNIFGDILSDEASMLTGSL 260 Query: 571 GLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDD 392 G++ S + +GK + E +HG+ G+ N +A+I + L R L+D Sbjct: 261 GMLPSASLDENGKGL-YEPSHGSAP------DIAGQNKANPLATILSLAMLL--RYSLND 311 Query: 391 NA 386 A Sbjct: 312 EA 313
>LEU3_GLUOX (Q5FUG5) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 369 Score = 32.7 bits (73), Expect = 1.2 Identities = 32/124 (25%), Positives = 51/124 (41%), Gaps = 5/124 (4%) Frame = -2 Query: 724 KYEAAGIWYEHRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLM 548 K E + H L D+ ++ + V N GD+ SD + GSLG++ S + Sbjct: 213 KREYPDVQLSHMLADNCAMQLVRDPNQFDVIVTGNLFGDILSDLASMLTGSLGMLPSATL 272 Query: 547 CP---DGK-TIEAEAAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARL 380 P DGK E HG+ G+ N +A I ++ L + ++A L Sbjct: 273 GPVRADGKRNALYEPIHGSAP------DIAGKGIANPLAQILSFAMLLRYSLNRAEDADL 326 Query: 379 LEFA 368 +E A Sbjct: 327 IEMA 330
>LEU3_SYNEL (P59029) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 361 Score = 32.7 bits (73), Expect = 1.2 Identities = 29/106 (27%), Positives = 45/106 (42%) Frame = -2 Query: 625 NYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNSI 446 N GD+ SD A GS+G++ S + G + E HG+ G+ N + Sbjct: 246 NLFGDILSDIAAMLTGSIGMLPSASLGESGPAL-FEPVHGSAP------DIAGQDKANPL 298 Query: 445 ASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDL 308 A + + + R L+ A AQ +EEA ++ G T DL Sbjct: 299 AMVL--SAAMMLRYGLNQPAA----AQAIEEAITAVLDQGYRTGDL 338
>LEU3_ANASP (Q8YXA2) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 362 Score = 32.7 bits (73), Expect = 1.2 Identities = 28/106 (26%), Positives = 46/106 (43%) Frame = -2 Query: 625 NYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNSI 446 N GD+ SD A GS+G++ S + G + E HG+ G+ N + Sbjct: 246 NLFGDILSDAAAMLTGSIGMLPSASLGASGPGV-FEPVHGSAP------DIAGQDKANPL 298 Query: 445 ASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDL 308 A + + + R LD + A K+E+A + +E G T D+ Sbjct: 299 AQVL--SAAMMLRYALDQP----QAADKIEQAVLQVLEQGDRTGDI 338
>LEU3_THEMA (Q9WZ26) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 354 Score = 32.7 bits (73), Expect = 1.2 Identities = 33/107 (30%), Positives = 46/107 (42%) Frame = -2 Query: 625 NYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNSI 446 N GD+ SD A GSLGL+ S G E A G+ G+ N I Sbjct: 239 NMFGDILSDESAALPGSLGLLPSASF---GDKNLYEPAGGSAP------DIAGKNIANPI 289 Query: 445 ASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDLA 305 A I + L H + ++E A+K+E A +E G T+D+A Sbjct: 290 AQILSLAMMLEH------SFGMVEEARKIERAVELVIEEGYRTRDIA 330
>LEU3_THETH (P61495) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 345 Score = 32.3 bits (72), Expect = 1.6 Identities = 36/134 (26%), Positives = 55/134 (41%), Gaps = 6/134 (4%) Frame = -2 Query: 733 WKSKYEAAGIWY-----EHRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSL 572 W+ E G Y EH+ +D + ++S + V N GD+ SD + GSL Sbjct: 195 WRKTVEEVGRGYPDVALEHQYVDAAAMHLVRSPARFDVVVTGNIFGDILSDLASVLPGSL 254 Query: 571 GLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDD 392 GL+ S + T E HG+ G+ N A+I + L H Sbjct: 255 GLLPSASL--GRGTPVFEPVHGSAP------DIAGKGIANPTAAILSAAMMLEHA----- 301 Query: 391 NARLLEFAQKLEEA 350 L+E A+K+E+A Sbjct: 302 -FGLVELARKVEDA 314
>LEU3_LACLA (Q02143) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 345 Score = 32.3 bits (72), Expect = 1.6 Identities = 34/131 (25%), Positives = 55/131 (41%), Gaps = 1/131 (0%) Frame = -2 Query: 697 EHRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEA 521 EH+L+D + + + V +N GD+ SD + GSLG+M S +G + Sbjct: 210 EHQLVDSCAMLLITNPQQFDVIVTENLFGDILSDEASSLAGSLGVMPSSSHGFNGLAL-Y 268 Query: 520 EAAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVG 341 E HG+ G+ N ++ I + L +D A + +E+A Sbjct: 269 EPIHGSAP------DIAGKGIANPVSMILSIAMMLRESFGQEDGAAM------IEKAVTQ 316 Query: 340 TVESGKMTKDL 308 T G +TKDL Sbjct: 317 TFTDGILTKDL 327
>LEU3_BUCUN (Q9EVI7) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 364 Score = 32.3 bits (72), Expect = 1.6 Identities = 38/156 (24%), Positives = 64/156 (41%), Gaps = 1/156 (0%) Frame = -2 Query: 694 HRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAE 518 H ID+ +K + V C N GD+ SD A GS+G++ S + + K E Sbjct: 224 HLYIDNATMQIIKDPNQFDVLLCSNLFGDIISDECAIITGSIGMLPSASL-NEKKFGLYE 282 Query: 517 AAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGT 338 A G+ G+ N IA I + + + + + L A K++ + + Sbjct: 283 PAGGSAP------DIEGKNIANPIAQILSVSMLVRY------SMNLKNIADKIDYSVISI 330 Query: 337 VESGKMTKDLALLVHGSSKVTRSDYLNTEEFIDAVA 230 ++ G T D+A ++YL T E D +A Sbjct: 331 LKKGYKTADIA---------HDNNYLKTNEMGDVIA 357
>LEU3_BUCBP (P59515) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 366 Score = 32.3 bits (72), Expect = 1.6 Identities = 39/156 (25%), Positives = 65/156 (41%), Gaps = 1/156 (0%) Frame = -2 Query: 694 HRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAE 518 H +D+ +K+ + V C N GD+ SD A GS+GL+ S + D E Sbjct: 223 HLYVDNAAMQIIKNPSQFDVLLCSNLFGDILSDECAAITGSIGLLPSASL-NDKNFGLYE 281 Query: 517 AAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGT 338 A G+ G+ N IA I + + + KL D A L+++A T Sbjct: 282 PAGGSAP------DIKGKNIANPIALILSIGMMMRYSFKLYDVADLIDWAVN------KT 329 Query: 337 VESGKMTKDLALLVHGSSKVTRSDYLNTEEFIDAVA 230 ++ G T+D++ + ++NT D +A Sbjct: 330 LKLGYRTQDIS---------ENNKFINTSSMGDIIA 356
>LEU3_GEOSL (Q748X2) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 362 Score = 32.3 bits (72), Expect = 1.6 Identities = 35/135 (25%), Positives = 57/135 (42%) Frame = -2 Query: 631 CKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTN 452 C+N GD+ SD A GSLG++ S + +G E + G+ G+ N Sbjct: 245 CENMFGDILSDEAAMLTGSLGMLPSASLA-EGTFGMYEPSGGSAP------DIAGQGIAN 297 Query: 451 SIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDLALLVHGSSKVTR 272 IA I L+ L + +++ A ++ A ++ G T+D+ G V Sbjct: 298 PIAQI------LSMGMMLKFSFGMVDAADAIDNAVATVLDQGFRTRDIYQQKDGEKLV-- 349 Query: 271 SDYLNTEEFIDAVAA 227 NT+E DA+ A Sbjct: 350 ----NTKEMGDAIIA 360
>LEU3_PSEHT (Q3IJS3) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 358 Score = 32.3 bits (72), Expect = 1.6 Identities = 36/120 (30%), Positives = 52/120 (43%), Gaps = 5/120 (4%) Frame = -2 Query: 640 VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGET 461 V C N GD+ SD A GS+GL+ S + G + E A G+ G+ Sbjct: 242 VLLCDNLFGDILSDECAMITGSMGLLPSASLNQSGFGL-YEPAGGSAP------DIAGKG 294 Query: 460 STNSIASIFAWTRGLAHRAKLDDNARLLEFA-QKLEEACVGTVE----SGKMTKDLALLV 296 N IA I + L + D+ AR +E A + A VGT + +G T D+A + Sbjct: 295 VANPIAQILSAALMLRYSLGQDEAARTIEKAVAEAVAAGVGTPDIFPNAGYTTNDVAAAI 354
>LEU3_METCA (Q606F4) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 360 Score = 32.0 bits (71), Expect = 2.1 Identities = 33/131 (25%), Positives = 55/131 (41%), Gaps = 1/131 (0%) Frame = -2 Query: 694 HRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAE 518 H +D+ +++ + V N GD+ SD A GS+G++ S + GK + E Sbjct: 220 HMYVDNAAMQLVRNPKQFDVMLTDNMFGDILSDCAAMLTGSIGMLPSASLAESGKGM-YE 278 Query: 517 AAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGT 338 HG+ G N IA+I + L R DD A+++ +A Sbjct: 279 PIHGSAP------DIAGRGIANPIATILSLAMML--RYSFDDAVS----AERIGKAVQTA 326 Query: 337 VESGKMTKDLA 305 ++ G T D+A Sbjct: 327 LDQGFRTADIA 337
>IDH_ECOLI (P08200) Isocitrate dehydrogenase [NADP] (EC 1.1.1.42)| (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific ICDH) (IDP) Length = 416 Score = 32.0 bits (71), Expect = 2.1 Identities = 34/136 (25%), Positives = 52/136 (38%) Frame = -2 Query: 640 VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGET 461 V AC N +GD SD LA G +G+ + + EA HGT ++ G+ Sbjct: 298 VIACMNLNGDYISDALAAQVGGIGIAPGANIGDECALF--EATHGTAPKY------AGQD 349 Query: 460 STNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDLALLVHGSSK 281 N + I + L H E A + + G + + +T D L+ G+ Sbjct: 350 KVNPGSIILSAEMMLRHMG-------WTEAADLIVKGMEGAINAKTVTYDFERLMDGAK- 401 Query: 280 VTRSDYLNTEEFIDAV 233 L EF DA+ Sbjct: 402 -----LLKCSEFGDAI 412
>LEU3_RALSO (Q8XXX5) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 356 Score = 32.0 bits (71), Expect = 2.1 Identities = 38/138 (27%), Positives = 59/138 (42%), Gaps = 15/138 (10%) Frame = -2 Query: 694 HRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAE 518 H +D+ +K+ + V N GD+ SD A GS+G++ S + + K + E Sbjct: 219 HMYVDNAAMQLVKAPKNFDVVVTGNMFGDILSDEAAMLTGSIGMLPSASLDANNKGL-YE 277 Query: 517 AAHGTVTRHFRVHQKGGETSTNSIASIFA------WTRGLAHRAKLDDNARLLEFAQK-- 362 +HG+ G+ N +A+I + +T G A +A +NA AQ Sbjct: 278 PSHGSAP------DIAGKGIANPLATILSAAMMLRYTLGKAEQADRIENAVKKVLAQGYR 331 Query: 361 ----LEEAC--VGTVESG 326 L C VGTVE G Sbjct: 332 TGDILTPGCKQVGTVEMG 349
>LEU3_NITOC (Q3JCC4) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 362 Score = 32.0 bits (71), Expect = 2.1 Identities = 33/130 (25%), Positives = 57/130 (43%), Gaps = 1/130 (0%) Frame = -2 Query: 694 HRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAE 518 H +D+ +++ + V N GD+ SD A GS+G++ S + G+ + E Sbjct: 220 HMYVDNAAMQLVRAPKQFDVVVTTNMFGDILSDCAAMLTGSIGMLPSASLDQSGRGM-YE 278 Query: 517 AAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGT 338 HG+ G+ N +A+I + L R LD A+ A +LE+A Sbjct: 279 PIHGSAP------DIAGQGIANPLATILSVAMML--RYSLDSPAQ----ATRLEKAVGAV 326 Query: 337 VESGKMTKDL 308 ++ G T D+ Sbjct: 327 LDQGLRTPDI 336
>ATG16_XENTR (Q5I0B9) Autophagy-related protein 16 (APG16-like 1)| Length = 537 Score = 32.0 bits (71), Expect = 2.1 Identities = 24/83 (28%), Positives = 36/83 (43%), Gaps = 7/83 (8%) Frame = -2 Query: 610 VQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTV-------TRHFRVHQKGGETSTN 452 VQ F A GF T V+ PDG + A +A GT+ + R+ K +S N Sbjct: 452 VQQTFSAPGFKCGSDWTRVIFSPDGSYVSAGSAEGTLYFWNVLTGKVERMFSKQHSSSIN 511 Query: 451 SIASIFAWTRGLAHRAKLDDNAR 383 ++ AW+ H +D +R Sbjct: 512 AV----AWSPSGTHVVSVDKGSR 530
>LEU3_OCEIH (Q8EN68) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 366 Score = 31.6 bits (70), Expect = 2.7 Identities = 31/111 (27%), Positives = 49/111 (44%), Gaps = 2/111 (1%) Frame = -2 Query: 694 HRLIDDMVAYALKSEGGY--VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEA 521 + L+ D A L ++ + V +N GD+ SD + GSLG++ S + DG + Sbjct: 214 NHLLVDAAAMKLVTQPSFFDVIVTENLFGDILSDEASVLTGSLGMLPSASLRADGLGL-Y 272 Query: 520 EAAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFA 368 E HG+ G+ N +A I + L H L D A+ +E A Sbjct: 273 EPVHGSAP------DIAGKGIANPLAMILSAALMLEHSFGLVDEAKEIERA 317
>LEU31_DECAR (Q47HR1) 3-isopropylmalate dehydrogenase 1 (EC 1.1.1.85) (Beta-IPM| dehydrogenase 1) (IMDH 1) (3-IPM-DH 1) Length = 350 Score = 31.6 bits (70), Expect = 2.7 Identities = 40/157 (25%), Positives = 66/157 (42%), Gaps = 1/157 (0%) Frame = -2 Query: 694 HRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAE 518 H L+D+ +K+ + V N GD+ SD + GS+G++ S + K + E Sbjct: 213 HMLVDNAAMQLVKAPKQFDVMVTGNMFGDILSDEASMLTGSIGMLPSASLDDKNKGL-YE 271 Query: 517 AAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGT 338 +HG+ G+ N +A+I + L + L+ E A ++E A Sbjct: 272 PSHGSAP------DIAGKGVANPLATILSAAMMLRYTFGLE------EQALRVENAVKKV 319 Query: 337 VESGKMTKDLALLVHGSSKVTRSDYLNTEEFIDAVAA 227 + G T D + G++KV T E DAV A Sbjct: 320 LAQGYRTGD--IYERGTNKV------GTREMGDAVLA 348
>LEU3_CEPAC (Q12545) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 380 Score = 31.6 bits (70), Expect = 2.7 Identities = 32/120 (26%), Positives = 48/120 (40%), Gaps = 3/120 (2%) Frame = -2 Query: 718 EAAGIWYEHRLIDDMVAYALKSEGGY--VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMC 545 E I +H+L D M ++ + V N GD+ SD G+LGLM S +C Sbjct: 217 EFPDITLQHQLADSMAMLMVRDPRRFNGVIHTDNTFGDILSDISGAITGTLGLMPSASLC 276 Query: 544 PDGKTIEAEAAHGTVTR-HFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFA 368 G E ++G H G+ N +A I + L + L+ A +E A Sbjct: 277 --GVPGEGHRSNGIYEPVHGSAPDISGKGLANPVAQILSVAMMLRYSMGLEKEATAVERA 334
>OM25_BRUCA (Q45110) 25 kDa outer-membrane immunogenic protein precursor| Length = 213 Score = 31.2 bits (69), Expect = 3.6 Identities = 34/131 (25%), Positives = 53/131 (40%), Gaps = 7/131 (5%) Frame = -2 Query: 679 DMVAYALKSEGGYVWACKNYDGDVQSDFLAQGF-GSLGLMTSVLMCPDGKTIEAEAAHGT 503 D + Y ++ + GY WA K+ DG + QGF GSL + P + A A Sbjct: 87 DQIVYGVEGDAGYSWAKKSKDGLE----VKQGFEGSLRARVGYDLNPVMPYLTAGIAGSQ 142 Query: 502 VTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNA------RLLEFAQKLEEACVG 341 + + + GE+ WT G AKL DN R +++ K + Sbjct: 143 IKLN---NGLDGESKFR-----VGWTAGAGLEAKLTDNILGRVEYRYTQYSNKNYDLAGT 194 Query: 340 TVESGKMTKDL 308 TV + T+D+ Sbjct: 195 TVRNKLDTQDI 205
>LEU3_PSYAR (Q4FRV0) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 367 Score = 31.2 bits (69), Expect = 3.6 Identities = 33/138 (23%), Positives = 56/138 (40%), Gaps = 1/138 (0%) Frame = -2 Query: 718 EAAGIWYEHRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCP 542 E + + H D+ +K + V N GD+ SD A GS+G++ S + Sbjct: 218 EYSDVALSHMYADNACMQLIKDPKQFDVMVTGNLFGDILSDEAAMLTGSIGMLPSASLDE 277 Query: 541 DGKTIEAEAAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQK 362 GK + E HG+ G+ N +A+I + L + K + AQ Sbjct: 278 AGKGM-YEPCHGSAP------DIAGQDIANPLATILSVAMMLRYTFKQE------VAAQA 324 Query: 361 LEEACVGTVESGKMTKDL 308 +E+A ++ G T D+ Sbjct: 325 IEQAVSDVLDDGLRTVDI 342
>LEU3_BURCE (Q845W3) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 355 Score = 31.2 bits (69), Expect = 3.6 Identities = 34/139 (24%), Positives = 58/139 (41%), Gaps = 1/139 (0%) Frame = -2 Query: 718 EAAGIWYEHRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCP 542 E A + H +D+ K+ + V N GD+ SD + GS+G++ S + Sbjct: 210 EYADVELSHMYVDNAAMQLAKAPKQFDVIVTGNMFGDILSDEASMLTGSIGMLPSASLDK 269 Query: 541 DGKTIEAEAAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQK 362 + K + E +HG+ G+ N +A+I L+ L + E A + Sbjct: 270 NNKGL-YEPSHGSAP------DIAGKGIANPLATI------LSAAMLLRYSLNRAEQADR 316 Query: 361 LEEACVGTVESGKMTKDLA 305 +E A +E G T D+A Sbjct: 317 IERAVKTVLEQGYRTGDIA 335
>LEU3_STAS1 (Q49Z13) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 346 Score = 31.2 bits (69), Expect = 3.6 Identities = 34/132 (25%), Positives = 55/132 (41%), Gaps = 3/132 (2%) Frame = -2 Query: 694 HRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAE 518 H L+D + + + + V +N GD+ SD + GSLGL S G + E Sbjct: 213 HLLVDACAMHLITNPSQFDVIVTENLFGDILSDEASVIPGSLGLSPSASFSEQGPRLY-E 271 Query: 517 AAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAH--RAKLDDNARLLEFAQKLEEACV 344 HG+ + + IA+ F +A R L+++ + A KLE Sbjct: 272 PIHGSAP----------DIANQDIANPFGMLLSVAMCLRESLNED----KAADKLENVIY 317 Query: 343 GTVESGKMTKDL 308 ++ GK T+DL Sbjct: 318 QLIKEGKTTRDL 329
>LEU3_PSEF5 (Q4KF05) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 360 Score = 30.8 bits (68), Expect = 4.7 Identities = 38/157 (24%), Positives = 67/157 (42%), Gaps = 1/157 (0%) Frame = -2 Query: 694 HRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAE 518 H +D+ +++ + V N GD+ SD + GS+G++ S + + K + E Sbjct: 220 HMYVDNAAMQLVRAPKQFDVIVTDNMFGDILSDEASMLTGSIGMLPSASLDANNKGM-YE 278 Query: 517 AAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGT 338 HG+ G+ N +A+I + + L + + L E A +E+A Sbjct: 279 PCHGSAP------DIAGQGIANPLATILSVSMMLRY------SFNLTEAADAIEQAVSRV 326 Query: 337 VESGKMTKDLALLVHGSSKVTRSDYLNTEEFIDAVAA 227 ++ G T D + G +KV T+E DAV A Sbjct: 327 LDQGLRTGD--IWSAGCTKV------GTQEMGDAVVA 355
>LEU3_SYNP6 (Q5MZ40) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 365 Score = 30.8 bits (68), Expect = 4.7 Identities = 28/106 (26%), Positives = 46/106 (43%) Frame = -2 Query: 625 NYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNSI 446 N GD+ SD A GS+G++ S + +G + E HG+ G+ N + Sbjct: 246 NLFGDILSDIAAMLTGSIGMLPSASLGAEGPGV-FEPVHGSAP------DIAGQDKANPL 298 Query: 445 ASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDL 308 A + + + R LD+ E A ++E A ++ G T DL Sbjct: 299 AQVL--SAAMMLRYGLDEP----EAAARIEAAVNQVLDQGYRTGDL 338
>LEU3_STRR6 (Q8DPJ4) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 345 Score = 30.8 bits (68), Expect = 4.7 Identities = 31/131 (23%), Positives = 59/131 (45%), Gaps = 1/131 (0%) Frame = -2 Query: 697 EHRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEA 521 EH+L+D + + + V +N GD+ SD + G+LG+M S +G ++ Sbjct: 211 EHQLVDSAAMLMITNPAKFDVIVTENLFGDILSDESSVLSGTLGVMPSASHSENGPSL-Y 269 Query: 520 EAAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVG 341 E HG+ G+ N I+ I L+ L D+ E ++++ A Sbjct: 270 EPIHGSAP------DIAGQGIANPISMI------LSVVMMLRDSFGRYEDTERIKRAVET 317 Query: 340 TVESGKMTKDL 308 ++ +G +T+D+ Sbjct: 318 SLAAGILTRDI 328
>LEU3_PROMT (Q46LE2) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 359 Score = 30.8 bits (68), Expect = 4.7 Identities = 33/130 (25%), Positives = 52/130 (40%), Gaps = 1/130 (0%) Frame = -2 Query: 694 HRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAE 518 H+ +D+ +++ + V N GD+ SD A GS+G++ S + DG + E Sbjct: 220 HQYVDNAAMQLVRNPSQFDVILTGNLFGDILSDIAAMLTGSIGMLPSASLTTDGPGV-FE 278 Query: 517 AAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGT 338 HG+ + + IA+ A A K+ N E A LE A Sbjct: 279 PVHGSAP----------DIAGKDIANPIAMLLSAAMMLKIALNE--TEAATFLENAINEI 326 Query: 337 VESGKMTKDL 308 + G T DL Sbjct: 327 LNDGYRTSDL 336
>LEU3_ACIAD (Q6FEV6) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 359 Score = 30.8 bits (68), Expect = 4.7 Identities = 35/143 (24%), Positives = 61/143 (42%), Gaps = 15/143 (10%) Frame = -2 Query: 706 IWYEHRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKT 530 I H +D+ +++ + V N GD+ SD A GS+G++ S + +GK Sbjct: 217 IQLSHMYVDNAAMQLVRAPKQFDVIVTGNLFGDILSDEAAMLTGSIGMLPSASLDENGKG 276 Query: 529 IEAEAAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFA--QKLE 356 + E HG+ G+ N +A+I + L + + + A+ +E A Q L+ Sbjct: 277 M-YEPCHGSAP------DIAGQNVANPLATILSVAMMLRYTFREEAAAKAIEDAVGQVLD 329 Query: 355 EAC------------VGTVESGK 323 + VGTVE G+ Sbjct: 330 QGLRTADIMSEGMQRVGTVEMGQ 352
>LEU3_THEAQ (P24098) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 344 Score = 30.8 bits (68), Expect = 4.7 Identities = 31/111 (27%), Positives = 48/111 (43%), Gaps = 1/111 (0%) Frame = -2 Query: 697 EHRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEA 521 +H+ +D M + +K+ + V N GD+ SD + GSLGL+ S + T Sbjct: 212 DHQYVDAMAMHLVKNPARFDVVVTGNIFGDILSDLASVLPGSLGLLPSASL--GRGTPVF 269 Query: 520 EAAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFA 368 E HG+ G+ N A+I + L H L + AR +E A Sbjct: 270 EPVHGSAP------DIAGKGIANPTAAILSAAMMLEHAFGLVELARRVEAA 314
>LEU3_SILPO (Q5LWZ5) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 367 Score = 30.8 bits (68), Expect = 4.7 Identities = 31/106 (29%), Positives = 43/106 (40%) Frame = -2 Query: 625 NYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNSI 446 N GD+ SD A GSLG++ S + +A + V H G+ N I Sbjct: 244 NLFGDILSDCAAMLTGSLGMLPSASLGAPMANGRPKALYEPV--HGSAPDIAGQGKANPI 301 Query: 445 ASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDL 308 A I ++ +A R D A A +LE A + G T DL Sbjct: 302 ACILSF--AMALRYSFDQGAE----ADRLEAAVEQVLADGVRTADL 341
>LEU3_BURPS (Q63JL2) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 355 Score = 30.8 bits (68), Expect = 4.7 Identities = 34/139 (24%), Positives = 57/139 (41%), Gaps = 1/139 (0%) Frame = -2 Query: 718 EAAGIWYEHRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCP 542 E A + H +D+ K+ + V N GD+ SD + GS+G++ S + Sbjct: 210 EYADVELSHMYVDNAAMQLAKAPKQFDVIVTGNMFGDILSDEASMLTGSIGMLPSASLDQ 269 Query: 541 DGKTIEAEAAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQK 362 K + E +HG+ G+ N +A+I L+ L + E A + Sbjct: 270 RNKGL-YEPSHGSAP------DIAGKGIANPLATI------LSAAMLLRYSLNRAEQADR 316 Query: 361 LEEACVGTVESGKMTKDLA 305 +E A +E G T D+A Sbjct: 317 IERAVKAVLEQGYRTGDIA 335
>LEU3_BURMA (Q62AI9) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 355 Score = 30.8 bits (68), Expect = 4.7 Identities = 34/139 (24%), Positives = 57/139 (41%), Gaps = 1/139 (0%) Frame = -2 Query: 718 EAAGIWYEHRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCP 542 E A + H +D+ K+ + V N GD+ SD + GS+G++ S + Sbjct: 210 EYADVELSHMYVDNAAMQLAKAPKQFDVIVTGNMFGDILSDEASMLTGSIGMLPSASLDQ 269 Query: 541 DGKTIEAEAAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQK 362 K + E +HG+ G+ N +A+I L+ L + E A + Sbjct: 270 RNKGL-YEPSHGSAP------DIAGKGIANPLATI------LSAAMLLRYSLNRAEQADR 316 Query: 361 LEEACVGTVESGKMTKDLA 305 +E A +E G T D+A Sbjct: 317 IERAVKAVLEQGYRTGDIA 335
>OM25_BRUSU (Q45689) 25 kDa outer-membrane immunogenic protein precursor| Length = 213 Score = 30.4 bits (67), Expect = 6.1 Identities = 35/142 (24%), Positives = 55/142 (38%), Gaps = 7/142 (4%) Frame = -2 Query: 712 AGIWYEHRLIDDMVAYALKSEGGYVWACKNYDGDVQSDFLAQGF-GSLGLMTSVLMCPDG 536 AG + D + Y ++ + GY WA K+ DG + QGF GSL + P Sbjct: 76 AGAFAGWNFQQDQIVYGVEGDAGYSWAKKSKDGLE----VKQGFEGSLRARVGYDLNPVM 131 Query: 535 KTIEAEAAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNA------RLLE 374 + A G +++ + S + WT G AKL DN R + Sbjct: 132 PYLTA----GIAGSQIKLNNGLDDESKFRV----GWTAGAGLEAKLTDNILGRVEYRYTQ 183 Query: 373 FAQKLEEACVGTVESGKMTKDL 308 + K + TV + T+D+ Sbjct: 184 YGNKNYDLAGTTVRNKLDTQDI 205
>OM25_BRUAB (Q44664) 25 kDa outer-membrane immunogenic protein precursor| Length = 213 Score = 30.4 bits (67), Expect = 6.1 Identities = 35/142 (24%), Positives = 55/142 (38%), Gaps = 7/142 (4%) Frame = -2 Query: 712 AGIWYEHRLIDDMVAYALKSEGGYVWACKNYDGDVQSDFLAQGF-GSLGLMTSVLMCPDG 536 AG + D + Y ++ + GY WA K+ DG + QGF GSL + P Sbjct: 76 AGAFAGWNFQQDQIVYGVEGDAGYSWAKKSKDGLE----VKQGFEGSLRARVGYDLNPVM 131 Query: 535 KTIEAEAAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNA------RLLE 374 + A G +++ + S + WT G AKL DN R + Sbjct: 132 PYLTA----GIAGSQIKLNNGLDDESKFRV----GWTAGAGLEAKLTDNILGRVEYRYTQ 183 Query: 373 FAQKLEEACVGTVESGKMTKDL 308 + K + TV + T+D+ Sbjct: 184 YGNKNYDLAGTTVRNKLDTQDI 205
>INHBA_SHEEP (P43032) Inhibin beta A chain precursor (Activin beta-A chain)| Length = 425 Score = 30.4 bits (67), Expect = 6.1 Identities = 24/97 (24%), Positives = 49/97 (50%), Gaps = 1/97 (1%) Frame = -2 Query: 523 AEAAHGTVTRHFRVHQKGGETSTNSIASIFAWTR-GLAHRAKLDDNARLLEFAQKLEEAC 347 AE+ T HF + Q+G + S A I+ + + A+R + RL + + L+ Sbjct: 127 AESGTARKTLHFEISQEGSDLSVVERAEIWLFLKVPKANRTRSKVTIRLFQQQKHLQ--- 183 Query: 346 VGTVESGKMTKDLALLVHGSSKVTRSDYLNTEEFIDA 236 G++++G+ +++ L K +S+ L +E+ +DA Sbjct: 184 -GSLDAGEEAEEVGL------KGEKSEMLISEKVVDA 213
>LEU3_BUCUL (Q9AQC8) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) (Fragment) Length = 126 Score = 30.4 bits (67), Expect = 6.1 Identities = 31/134 (23%), Positives = 55/134 (41%) Frame = -2 Query: 631 CKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTN 452 C N GD+ SD A GS+G++ S + E A G+ G+ N Sbjct: 8 CSNLFGDIISDECAVITGSIGMLPSASFNEKNFGL-YEPAGGSAP------DIAGKNIAN 60 Query: 451 SIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDLALLVHGSSKVTR 272 IA I + + + + KL + A K++++ +++G T D++ Sbjct: 61 PIAQILSLSMLVRYGMKLK------KIADKIDKSVASALKAGYRTADIS---------NN 105 Query: 271 SDYLNTEEFIDAVA 230 + YL T E D ++ Sbjct: 106 NSYLKTNEMGDVIS 119
>LEU3_PROMP (Q7V1R9) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 357 Score = 30.4 bits (67), Expect = 6.1 Identities = 31/127 (24%), Positives = 51/127 (40%), Gaps = 1/127 (0%) Frame = -2 Query: 685 IDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAH 509 +D+ +K G + V N GD+ SD A GS+G++ S + G + E H Sbjct: 223 VDNAAMQLVKDPGQFDVILTSNLFGDILSDLAAMITGSIGMLPSASLSNSGPGV-FEPVH 281 Query: 508 GTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVES 329 G+ + + +IA+ A + K+ N +E A +E A + Sbjct: 282 GSAP----------DIAGKNIANPIAMALSTSMMLKIGLNE--IEAADDIEIAIDNVLSK 329 Query: 328 GKMTKDL 308 G T DL Sbjct: 330 GYRTSDL 336
>LEU3_PROMM (Q7V842) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 357 Score = 30.4 bits (67), Expect = 6.1 Identities = 30/126 (23%), Positives = 51/126 (40%), Gaps = 6/126 (4%) Frame = -2 Query: 733 WKSKYEAAGIWY-----EHRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSL 572 W+ + +A Y H +D+ +++ + V N GD+ SD A GS+ Sbjct: 202 WRDRVDALAANYGDVELSHMYVDNAAMQLVRNPRQFDVLLTGNLFGDILSDEAAMLTGSI 261 Query: 571 GLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDD 392 G++ S + +G + E HG+ G+ N +A + L K +D Sbjct: 262 GMLPSASLGSEGPGL-FEPVHGSAP------DIAGQDLANPMAMVLCAAMMLRIGLKEND 314 Query: 391 NARLLE 374 AR LE Sbjct: 315 AARALE 320
>LEU3_BLOFL (Q7VQJ7) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 364 Score = 30.0 bits (66), Expect = 8.0 Identities = 35/158 (22%), Positives = 65/158 (41%), Gaps = 1/158 (0%) Frame = -2 Query: 697 EHRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEA 521 +H +D+ +++ + V C N GD+ SD A+ GS+G++ S + + Sbjct: 223 QHLYVDNASMQLIRNPSAFDVILCPNLFGDILSDECAEINGSIGILPSASLNEHNFGL-Y 281 Query: 520 EAAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVG 341 E A G+ G+ N IA I + + KL+ A +E+A Sbjct: 282 EPAGGSAP------DIAGKNIANPIAQILSTALLFRYSLKLN------HVAITIEKAVYK 329 Query: 340 TVESGKMTKDLALLVHGSSKVTRSDYLNTEEFIDAVAA 227 + G T+D+A + +NT++ D +A+ Sbjct: 330 ALTLGYRTQDIA--------YNKQKSVNTDDMGDIIAS 359
>LEU3_BUCAI (P56933) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 363 Score = 30.0 bits (66), Expect = 8.0 Identities = 38/173 (21%), Positives = 68/173 (39%), Gaps = 6/173 (3%) Frame = -2 Query: 733 WKSKYEAAGIWY-----EHRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSL 572 W+ E+ Y H ID+ +K + V C N GD+ SD A GS+ Sbjct: 205 WREVVESVSKKYPDVHLSHLYIDNAAMQIIKDPNQFDVLLCSNLFGDIISDECATITGSI 264 Query: 571 GLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDD 392 G++ S + E A G+ G+ N IA I + + + + L+ Sbjct: 265 GMLPSASFNEKNFGL-YEPAGGSAP------DIEGKNIANPIAQILSLSMLVRYGMNLN- 316 Query: 391 NARLLEFAQKLEEACVGTVESGKMTKDLALLVHGSSKVTRSDYLNTEEFIDAV 233 + A K+++A ++ G T D++ +++L T+E D + Sbjct: 317 -----QIADKIDKAVNNVLKKGYRTSDIS---------HDNNFLKTDEMGDLI 355
>Y1185_METJA (Q58585) Hypothetical protein MJ1185| Length = 622 Score = 30.0 bits (66), Expect = 8.0 Identities = 22/62 (35%), Positives = 34/62 (54%) Frame = -3 Query: 543 LMVKQSKPKLPMAQSLVISVFTRKVVKPAQTALLPSLLGQEDLHTGQS*TTTLDFLNLHR 364 L+V+ K +LP+ ++L I F RK +KP L+ LLG ED+ D +NL+R Sbjct: 504 LVVESIKLELPI-ENLGICRFHRKWLKPVLKELVKELLGIEDI--------VEDSINLYR 554 Query: 363 NL 358 + Sbjct: 555 EI 556
>LEU3_BACCA (P05644) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 366 Score = 30.0 bits (66), Expect = 8.0 Identities = 25/96 (26%), Positives = 40/96 (41%) Frame = -2 Query: 718 EAAGIWYEHRLIDDMVAYALKSEGGYVWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPD 539 E + EH L+D + + V +N GD+ SD + GSLG++ S + Sbjct: 211 EFPDVTLEHMLVDMRMQLIRAPKQFDVIVTENMFGDILSDEASMLSGSLGMLPSASLSAS 270 Query: 538 GKTIEAEAAHGTVTRHFRVHQKGGETSTNSIASIFA 431 G ++ E HG+ G N IA+I + Sbjct: 271 GPSL-YEPVHGSAP------DIAGMNKANPIAAILS 299
>IDH_SYNY3 (P80046) Isocitrate dehydrogenase [NADP] (EC 1.1.1.42)| (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific ICDH) (IDP) Length = 475 Score = 30.0 bits (66), Expect = 8.0 Identities = 25/93 (26%), Positives = 42/93 (45%), Gaps = 6/93 (6%) Frame = -2 Query: 751 EIYEAGWKSKYEAAGIWYEHRLIDDMVAYAL------KSEGGYVWACKNYDGDVQSDFLA 590 ++ + W+S G W E +++D +A ++ + + + A N +GD SD A Sbjct: 312 QVLNSIWES--HGNGQWKEKVMVNDRIADSIFQQIQTRPDEYSILATMNLNGDYLSDAAA 369 Query: 589 QGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRH 491 G LG+ + D I EA HGT +H Sbjct: 370 AVVGGLGMGPGANI-GDSAAI-FEATHGTAPKH 400
>LEU3_PICST (O94114) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 373 Score = 30.0 bits (66), Expect = 8.0 Identities = 44/146 (30%), Positives = 60/146 (41%), Gaps = 7/146 (4%) Frame = -2 Query: 724 KYEAAGIWYEHRLIDDMVAYALKSE---GGYVWACKNYDGDVQSDFLAQGFGSLGLMTSV 554 K E + +H+LID ++S G V N G + SD + GSLGL+ S Sbjct: 217 KEEFPQLTIQHQLIDSAAMILVQSPTKLNGIV-ITSNMFGYIISDEASVIPGSLGLLPSA 275 Query: 553 LMCPDGKTIEA----EAAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNA 386 + T A E HG+ E N IA+I + L R LD Sbjct: 276 SLASLPDTNSAFGLYEPCHGSAPDL-------PENKVNPIATILSVAMML--RLSLDS-- 324 Query: 385 RLLEFAQKLEEACVGTVESGKMTKDL 308 L+ A+ LEEA ++SG T DL Sbjct: 325 --LKEAEALEEAVRQVLDSGVRTADL 348
>LEU3_THETN (Q8RDK0) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 355 Score = 30.0 bits (66), Expect = 8.0 Identities = 39/155 (25%), Positives = 62/155 (40%), Gaps = 1/155 (0%) Frame = -2 Query: 694 HRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAE 518 H +D+ +K+ + V N GD+ SD AQ GS+G++ S + D + E Sbjct: 218 HMYVDNCAMQLVKNPFQFDVILTNNMFGDILSDEAAQIVGSIGILPSASLRGDRVGL-YE 276 Query: 517 AAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGT 338 HG+ G+ N +A+I + L + + E AQ + +A Sbjct: 277 PIHGSAP------DIAGKKIANPLATILSVAMMLQYSFGEE------EAAQDIRKAVERA 324 Query: 337 VESGKMTKDLALLVHGSSKVTRSDYLNTEEFIDAV 233 +E G T DL + L+TEE D V Sbjct: 325 LEEGFRTADLG----------KGIVLSTEEMGDKV 349 Database: uniprot_sprot.fasta Posted date: May 25, 2006 5:36 PM Number of letters in database: 80,573,946 Number of sequences in database: 219,361 Lambda K H 0.318 0.135 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 100,249,467 Number of Sequences: 219361 Number of extensions: 1917567 Number of successful extensions: 5498 Number of sequences better than 10.0: 160 Number of HSP's better than 10.0 without gapping: 5302 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 5464 length of database: 80,573,946 effective HSP length: 110 effective length of database: 56,444,236 effective search space used: 7902193040 frameshift window, decay const: 50, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
