ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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| Clone Name | rbasd26m04 |
|---|---|
| Clone Library Name | barley_pub |
>FDH_HORVU (Q9ZRI8) Formate dehydrogenase, mitochondrial precursor (EC| 1.2.1.2) (NAD-dependent formate dehydrogenase) (FDH) Length = 377 Score = 353 bits (907), Expect = 2e-97 Identities = 169/170 (99%), Positives = 169/170 (99%) Frame = -1 Query: 664 RXKPFNCNLLYHDRLQINPELEKEIGAKFEEDLDAMLPKCDVVVINTPLTEKTRGMFNKE 485 R KPFNCNLLYHDRLQINPELEKEIGAKFEEDLDAMLPKCDVVVINTPLTEKTRGMFNKE Sbjct: 208 RLKPFNCNLLYHDRLQINPELEKEIGAKFEEDLDAMLPKCDVVVINTPLTEKTRGMFNKE 267 Query: 484 KIAKMKKGVIIVNNARGAIMDTQAVADACSSGHIAGYGGDVWFPQPAPKDHPWRYMPNHA 305 KIAKMKKGVIIVNNARGAIMDTQAVADACSSGHIAGYGGDVWFPQPAPKDHPWRYMPNHA Sbjct: 268 KIAKMKKGVIIVNNARGAIMDTQAVADACSSGHIAGYGGDVWFPQPAPKDHPWRYMPNHA 327 Query: 304 MTPHISGTTIDAQLRYAAGVKDMLDRYFKGEEFPVENYIVKEGELASQYK 155 MTPHISGTTIDAQLRYAAGVKDMLDRYFKGEEFPVENYIVKEGELASQYK Sbjct: 328 MTPHISGTTIDAQLRYAAGVKDMLDRYFKGEEFPVENYIVKEGELASQYK 377
>FDH1_ORYSA (Q9SXP2) Formate dehydrogenase 1, mitochondrial precursor (EC| 1.2.1.2) (NAD-dependent formate dehydrogenase 1) (FDH 1) Length = 376 Score = 339 bits (869), Expect = 5e-93 Identities = 158/170 (92%), Positives = 168/170 (98%) Frame = -1 Query: 664 RXKPFNCNLLYHDRLQINPELEKEIGAKFEEDLDAMLPKCDVVVINTPLTEKTRGMFNKE 485 R KPFNCNLLYHDRL+I+PELEKEIGAK+EEDLDAMLPKCDV+VINTPLTEKTRGMFNKE Sbjct: 207 RLKPFNCNLLYHDRLKIDPELEKEIGAKYEEDLDAMLPKCDVIVINTPLTEKTRGMFNKE 266 Query: 484 KIAKMKKGVIIVNNARGAIMDTQAVADACSSGHIAGYGGDVWFPQPAPKDHPWRYMPNHA 305 +IAKMKKGVIIVNNARGAIMDTQAVADACSSG +AGYGGDVWFPQPAPKDHPWRYMPNHA Sbjct: 267 RIAKMKKGVIIVNNARGAIMDTQAVADACSSGQVAGYGGDVWFPQPAPKDHPWRYMPNHA 326 Query: 304 MTPHISGTTIDAQLRYAAGVKDMLDRYFKGEEFPVENYIVKEGELASQYK 155 MTPHISGTTIDAQLRYAAGVKDMLDRYFKGE+FPV+NYIVKEG+LASQY+ Sbjct: 327 MTPHISGTTIDAQLRYAAGVKDMLDRYFKGEDFPVQNYIVKEGQLASQYQ 376
>FDH2_ORYSA (Q67U69) Formate dehydrogenase 2, mitochondrial precursor (EC| 1.2.1.2) (NAD-dependent formate dehydrogenase 2) (FDH 2) Length = 378 Score = 328 bits (840), Expect = 1e-89 Identities = 151/170 (88%), Positives = 163/170 (95%) Frame = -1 Query: 664 RXKPFNCNLLYHDRLQINPELEKEIGAKFEEDLDAMLPKCDVVVINTPLTEKTRGMFNKE 485 R KPFNCNL+YHDR++I+PELEKEIGAK+EEDLDAMLPKCDVVVIN PLTEKTRGMFNKE Sbjct: 209 RLKPFNCNLMYHDRVKIDPELEKEIGAKYEEDLDAMLPKCDVVVINMPLTEKTRGMFNKE 268 Query: 484 KIAKMKKGVIIVNNARGAIMDTQAVADACSSGHIAGYGGDVWFPQPAPKDHPWRYMPNHA 305 +IAKMKKGV IVNNARGAIMDTQAVADAC+SGH+AGYGGDVWFPQPAPKDHPWRYMPNHA Sbjct: 269 RIAKMKKGVTIVNNARGAIMDTQAVADACASGHVAGYGGDVWFPQPAPKDHPWRYMPNHA 328 Query: 304 MTPHISGTTIDAQLRYAAGVKDMLDRYFKGEEFPVENYIVKEGELASQYK 155 MTPH SGTTID QLRYAAGVKDMLDRYFKGE+FP +NYIVK G+LASQY+ Sbjct: 329 MTPHCSGTTIDGQLRYAAGVKDMLDRYFKGEDFPAQNYIVKAGQLASQYQ 378
>FDH_SOLTU (Q07511) Formate dehydrogenase, mitochondrial precursor (EC| 1.2.1.2) (NAD-dependent formate dehydrogenase) (FDH) Length = 381 Score = 313 bits (803), Expect = 2e-85 Identities = 144/170 (84%), Positives = 159/170 (93%) Frame = -1 Query: 664 RXKPFNCNLLYHDRLQINPELEKEIGAKFEEDLDAMLPKCDVVVINTPLTEKTRGMFNKE 485 R KPFNCNLLYHDRL+++ ELE +IGAKFEEDLD ML KCD+VVINTPLTEKT+GMF+KE Sbjct: 212 RLKPFNCNLLYHDRLKMDSELENQIGAKFEEDLDKMLSKCDIVVINTPLTEKTKGMFDKE 271 Query: 484 KIAKMKKGVIIVNNARGAIMDTQAVADACSSGHIAGYGGDVWFPQPAPKDHPWRYMPNHA 305 +IAK+KKGV+IVNNARGAIMDTQAV DAC+SGHIAGY GDVW+PQPAPKDHPWRYMPN A Sbjct: 272 RIAKLKKGVLIVNNARGAIMDTQAVVDACNSGHIAGYSGDVWYPQPAPKDHPWRYMPNQA 331 Query: 304 MTPHISGTTIDAQLRYAAGVKDMLDRYFKGEEFPVENYIVKEGELASQYK 155 MTPHISGTTIDAQLRYAAG KDMLDRYFKGE+FP ENYIVK+GELA QY+ Sbjct: 332 MTPHISGTTIDAQLRYAAGTKDMLDRYFKGEDFPAENYIVKDGELAPQYR 381
>FDH_ARATH (Q9S7E4) Formate dehydrogenase, mitochondrial precursor (EC| 1.2.1.2) (NAD-dependent formate dehydrogenase) (FDH) Length = 384 Score = 296 bits (759), Expect = 3e-80 Identities = 139/170 (81%), Positives = 149/170 (87%) Frame = -1 Query: 664 RXKPFNCNLLYHDRLQINPELEKEIGAKFEEDLDAMLPKCDVVVINTPLTEKTRGMFNKE 485 R KPF CNLLYHDRLQ+ PELEKE GAKF EDL+ MLPKCDV+VIN PLTEKTRGMFNKE Sbjct: 215 RLKPFGCNLLYHDRLQMAPELEKETGAKFVEDLNEMLPKCDVIVINMPLTEKTRGMFNKE 274 Query: 484 KIAKMKKGVIIVNNARGAIMDTQAVADACSSGHIAGYGGDVWFPQPAPKDHPWRYMPNHA 305 I K+KKGV+IVNNARGAIM+ QAV DA SGHI GY GDVW PQPAPKDHPWRYMPN A Sbjct: 275 LIGKLKKGVLIVNNARGAIMERQAVVDAVESGHIGGYSGDVWDPQPAPKDHPWRYMPNQA 334 Query: 304 MTPHISGTTIDAQLRYAAGVKDMLDRYFKGEEFPVENYIVKEGELASQYK 155 MTPH SGTTIDAQLRYAAG KDML+RYFKGE+FP ENYIVK+GELA QY+ Sbjct: 335 MTPHTSGTTIDAQLRYAAGTKDMLERYFKGEDFPTENYIVKDGELAPQYR 384
>FDH_NEUCR (Q07103) Formate dehydrogenase (EC 1.2.1.2) (NAD-dependent formate| dehydrogenase) (FDH) Length = 375 Score = 185 bits (470), Expect = 9e-47 Identities = 95/175 (54%), Positives = 125/175 (71%), Gaps = 7/175 (4%) Frame = -1 Query: 664 RXKPFNCN-LLYHDRLQINPELEKEIGAKFEEDLDAMLPKCDVVVINTPLTEKTRGMFNK 488 R KPF+C LLY+D ++ E E EIG + DL+ ML +CDVV IN PL EKT+G+FNK Sbjct: 183 RLKPFDCKELLYYDYQPLSAEKEAEIGCRRVADLEEMLAQCDVVTINCPLHEKTQGLFNK 242 Query: 487 EKIAKMKKGVIIVNNARGAIMDTQAVADACSSGHIAGYGGDVWFPQPAPKDHPWRYMPN- 311 E I+KMKKG +VN ARGAI+ + VA+A SGH+ GYGGDVWFPQPAP+DHP RY N Sbjct: 243 ELISKMKKGSWLVNTARGAIVVKEDVAEALKSGHLRGYGGDVWFPQPAPQDHPLRYAKNP 302 Query: 310 ----HAMTPHISGTTIDAQLRYAAGVKDMLDRYFKGE-EFPVENYIVKEGELASQ 161 +AM PH+SGT++DAQ RYAAG K +++ Y G+ ++ E+ IV G+ A++ Sbjct: 303 FGGGNAMVPHMSGTSLDAQKRYAAGTKAIIESYLSGKHDYRPEDLIVYGGDYATK 357
>FDH_EMENI (Q03134) Probable formate dehydrogenase (EC 1.2.1.2) (NAD-dependent| formate dehydrogenase) (FDH) Length = 377 Score = 177 bits (449), Expect = 3e-44 Identities = 95/192 (49%), Positives = 126/192 (65%), Gaps = 24/192 (12%) Frame = -1 Query: 664 RXKPFNCN-LLYHDRLQINPELEKEIGAKFEEDLDAMLPKCDVVVINTPLTEKTRGMFNK 488 R KPF+C LLY+D + PE+EKEIGA+ + L+ M+ +CDVV IN PL EKTRG+FNK Sbjct: 178 RLKPFDCKELLYYDYQPLRPEVEKEIGARRVDSLEEMVSQCDVVTINCPLHEKTRGLFNK 237 Query: 487 EKIAKMK-----------------KGVIIVNNARGAIMDTQAVADACSSGHIAGYGGDVW 359 E I+KMK KG +VN ARGAI+ + VA+A SGH+ GYGGDVW Sbjct: 238 ELISKMKPGKSALLYLIIPMLMYHKGSWLVNTARGAIVVKEDVAEALKSGHLRGYGGDVW 297 Query: 358 FPQPAPKDHPWRYMPN-----HAMTPHISGTTIDAQLRYAAGVKDMLDRYFKGE-EFPVE 197 FPQPAPK+HP RY + +A PH+SGT++ AQ+RYA G K +LD YF G ++ + Sbjct: 298 FPQPAPKEHPLRYAEHPWGGGNATVPHMSGTSLAAQIRYANGTKAILDSYFSGRFDYQPQ 357 Query: 196 NYIVKEGELASQ 161 + IV G+ A++ Sbjct: 358 DLIVHGGDYATK 369
>FDH_PSESR (P33160) Formate dehydrogenase (EC 1.2.1.2) (NAD-dependent formate| dehydrogenase) (FDH) Length = 400 Score = 171 bits (434), Expect = 1e-42 Identities = 84/166 (50%), Positives = 107/166 (64%) Frame = -1 Query: 664 RXKPFNCNLLYHDRLQINPELEKEIGAKFEEDLDAMLPKCDVVVINTPLTEKTRGMFNKE 485 R PF+ +L Y DR ++ +EKE+ + + M P CDVV +N PL +T M N E Sbjct: 209 RLAPFDVHLHYTDRHRLPESVEKELNLTWHATREDMYPVCDVVTLNCPLHPETEHMINDE 268 Query: 484 KIAKMKKGVIIVNNARGAIMDTQAVADACSSGHIAGYGGDVWFPQPAPKDHPWRYMPNHA 305 + K+G IVN ARG + D AVA A SG +AGY GDVWFPQPAPKDHPWR MP + Sbjct: 269 TLKLFKRGAYIVNTARGKLCDRDAVARALESGRLAGYAGDVWFPQPAPKDHPWRTMPYNG 328 Query: 304 MTPHISGTTIDAQLRYAAGVKDMLDRYFKGEEFPVENYIVKEGELA 167 MTPHISGTT+ AQ RYAAG +++L+ +F+G E IV+ G LA Sbjct: 329 MTPHISGTTLTAQARYAAGTREILECFFEGRPIRDEYLIVQGGALA 374
>FDH_PICAN (P33677) Formate dehydrogenase (EC 1.2.1.2) (NAD-dependent formate| dehydrogenase) (FDH) Length = 361 Score = 150 bits (379), Expect = 3e-36 Identities = 72/145 (49%), Positives = 98/145 (67%), Gaps = 5/145 (3%) Frame = -1 Query: 640 LLYHDRLQINPELEKEIGAKFEEDLDAMLPKCDVVVINTPLTEKTRGMFNKEKIAKMKKG 461 LLY+D ++ E E+++GA+ D+ ++ + D+V IN PL ++G+ N E + KKG Sbjct: 190 LLYYDYQSLSKEAEEKVGARRVHDIKELVAQADIVTINCPLHAGSKGLVNAELLKHFKKG 249 Query: 460 VIIVNNARGAIMDTQAVADACSSGHIAGYGGDVWFPQPAPKDHPWRYMPN-----HAMTP 296 +VN ARGAI + VA A SG + GYGGDVWFPQPAPKDHPWR M N +AMTP Sbjct: 250 AWLVNTARGAICVAEDVAAAVKSGQLRGYGGDVWFPQPAPKDHPWRSMANKYGAGNAMTP 309 Query: 295 HISGTTIDAQLRYAAGVKDMLDRYF 221 H SG+ IDAQ+RYA G K++L+ +F Sbjct: 310 HYSGSVIDAQVRYAQGTKNILESFF 334
>FDH1_YEAST (Q08911) Formate dehydrogenase 1 (EC 1.2.1.2) (NAD-dependent| formate dehydrogenase 1) Length = 376 Score = 145 bits (367), Expect = 8e-35 Identities = 76/144 (52%), Positives = 101/144 (70%), Gaps = 6/144 (4%) Frame = -1 Query: 574 EDLDAMLPKCDVVVINTPLTEKTRGMFNKEKIAKMKKGVIIVNNARGAIMDTQAVADACS 395 E L+ M+ + DVV IN PL + +RG+FNK+ I+ MK G +VN ARGAI + VA+A Sbjct: 227 EKLEDMVAQSDVVTINCPLHKDSRGLFNKKLISHMKDGAYLVNTARGAICVAEDVAEAVK 286 Query: 394 SGHIAGYGGDVWFPQPAPKDHPWRYMPN-----HAMTPHISGTTIDAQLRYAAGVKDMLD 230 SG +AGYGGDVW QPAPKDHPWR M N +AMT HISGT++DAQ RYA GVK++L+ Sbjct: 287 SGKLAGYGGDVWDKQPAPKDHPWRTMDNKDHVGNAMTVHISGTSLDAQKRYAQGVKNILN 346 Query: 229 RYF-KGEEFPVENYIVKEGELASQ 161 YF K ++ ++ IV+ G A++ Sbjct: 347 SYFSKKFDYRPQDIIVQNGSYATR 370
>FDH2_YEAST (Q08987) Formate dehydrogenase 2 (EC 1.2.1.2) (NAD-dependent| formate dehydrogenase 2) Length = 376 Score = 143 bits (360), Expect = 5e-34 Identities = 75/144 (52%), Positives = 100/144 (69%), Gaps = 6/144 (4%) Frame = -1 Query: 574 EDLDAMLPKCDVVVINTPLTEKTRGMFNKEKIAKMKKGVIIVNNARGAIMDTQAVADACS 395 E L+ M+ + DVV IN PL + +RG+FNK+ I+ MK G +VN ARGAI + VA+A Sbjct: 227 EKLEDMVAQSDVVTINCPLHKDSRGLFNKKLISHMKDGAYLVNTARGAICVAEDVAEAVK 286 Query: 394 SGHIAGYGGDVWFPQPAPKDHPWRYMPN-----HAMTPHISGTTIDAQLRYAAGVKDMLD 230 SG +AGYGGDVW QPAPKDHPWR M N +AMT HISGT++ AQ RYA GVK++L+ Sbjct: 287 SGKLAGYGGDVWDKQPAPKDHPWRTMDNKDHVGNAMTVHISGTSLHAQKRYAQGVKNILN 346 Query: 229 RYF-KGEEFPVENYIVKEGELASQ 161 YF K ++ ++ IV+ G A++ Sbjct: 347 SYFSKKFDYRPQDIIVQNGSYATR 370
>SERA_BACSU (P35136) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (PGDH)| Length = 525 Score = 94.7 bits (234), Expect = 2e-19 Identities = 52/134 (38%), Positives = 81/134 (60%) Frame = -1 Query: 616 INPELEKEIGAKFEEDLDAMLPKCDVVVINTPLTEKTRGMFNKEKIAKMKKGVIIVNNAR 437 + E K+IG + +L D++ ++TPLT++T+G+ NKE IAK KKGV ++N AR Sbjct: 171 LTEERAKKIGVN-SRTFEEVLESADIITVHTPLTKETKGLLNKETIAKTKKGVRLINCAR 229 Query: 436 GAIMDTQAVADACSSGHIAGYGGDVWFPQPAPKDHPWRYMPNHAMTPHISGTTIDAQLRY 257 G I+D A+ +A +GH+AG DV+ +P P D+ P TPH+ +T +AQL Sbjct: 230 GGIIDEAALLEALENGHVAGAALDVFEVEP-PVDNKLVDHPLVIATPHLGASTKEAQLNV 288 Query: 256 AAGVKDMLDRYFKG 215 AA V + + ++ KG Sbjct: 289 AAQVSEEVLQFAKG 302
>GYAR_PYRAB (Q9UYR1) Glyoxylate reductase (EC 1.1.1.26) (Glycolate reductase)| Length = 335 Score = 93.6 bits (231), Expect = 5e-19 Identities = 56/154 (36%), Positives = 90/154 (58%) Frame = -1 Query: 664 RXKPFNCNLLYHDRLQINPELEKEIGAKFEEDLDAMLPKCDVVVINTPLTEKTRGMFNKE 485 R + F+ +LY+ R + PE+EKE+ A+F+ LD +L + D VV+ PL ++T M N+E Sbjct: 169 RARGFDMRILYYSRTR-KPEVEKELNAEFKP-LDELLRESDFVVLAVPLNKETYHMINEE 226 Query: 484 KIAKMKKGVIIVNNARGAIMDTQAVADACSSGHIAGYGGDVWFPQPAPKDHPWRYMPNHA 305 ++ MK+ I++N ARG ++DT+A+ A G IAG G DV+ +P + + + N Sbjct: 227 RLKMMKRTAILINVARGKVIDTKALIKALKEGWIAGAGLDVYEEEPYYNEELFS-LDNVV 285 Query: 304 MTPHISGTTIDAQLRYAAGVKDMLDRYFKGEEFP 203 +TPHI T A+ A V + L + +GE P Sbjct: 286 LTPHIGSATFGAREGMAKLVAENLIAFKRGEVPP 319
>SERA_ARCFU (O29445) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (PGDH)| Length = 527 Score = 92.8 bits (229), Expect = 8e-19 Identities = 55/159 (34%), Positives = 86/159 (54%) Frame = -1 Query: 664 RXKPFNCNLLYHDRLQINPELEKEIGAKFEEDLDAMLPKCDVVVINTPLTEKTRGMFNKE 485 R K N+L +D ++ E ++IG K D D +L DV+ ++ P T++T G+ K Sbjct: 157 RCKALEMNVLAYDPF-VSKERAEQIGVKLV-DFDTLLASSDVITVHVPRTKETIGLIGKG 214 Query: 484 KIAKMKKGVIIVNNARGAIMDTQAVADACSSGHIAGYGGDVWFPQPAPKDHPWRYMPNHA 305 + KMK GVI+VN ARG I+D A+ +A +G +A DV+ +P D+P + N Sbjct: 215 QFEKMKDGVIVVNAARGGIVDEAALYEAIKAGKVAAAALDVYEKEPPSPDNPLLKLDNVV 274 Query: 304 MTPHISGTTIDAQLRYAAGVKDMLDRYFKGEEFPVENYI 188 TPHI+ +T +AQL + + + KG PV N + Sbjct: 275 TTPHIAASTREAQLNVGMIIAEDIVNMAKG--LPVRNAV 311
>GYAR_AERPE (Q9YAW4) Glyoxylate reductase (EC 1.1.1.26) (Glycolate reductase)| Length = 335 Score = 92.8 bits (229), Expect = 8e-19 Identities = 55/161 (34%), Positives = 89/161 (55%), Gaps = 2/161 (1%) Frame = -1 Query: 658 KPFNCNLLYHDRLQINPELEKEIGAKFEEDLDAMLPKCDVVVINTPLTEKTRGMFNKEKI 479 K F ++YH R + E+EKE+GA++ L+ +L + D++ I+ PLT++TR + + ++ Sbjct: 171 KAFGMRIIYHSRSR-KREIEKELGAEYRS-LEDLLRESDILSIHLPLTDETRHLIGESEL 228 Query: 478 AKMKKGVIIVNNARGAIMDTQAVADACSSGHIAGYGGDVWFPQPAPKDHPWRYMPNHAMT 299 MKK I+VN RGAI+DT A+ A G IA DV+ +P +HP N + Sbjct: 229 KLMKKTAILVNTGRGAIVDTGALVKALREGWIAAAALDVFEEEPLNPNHPLTAFKNVVLA 288 Query: 298 PHISGTTIDAQLRYAAGVKDMLDRYFKGEEFP--VENYIVK 182 PH + T + +LR A + L + +G+ P V +VK Sbjct: 289 PHAASATRETRLRMAMMAAENLVAFAQGKVPPNLVNREVVK 329
>GYAR_PYRKO (Q5JEZ2) Glyoxylate reductase (EC 1.1.1.26) (Glycolate reductase)| Length = 333 Score = 92.0 bits (227), Expect = 1e-18 Identities = 61/163 (37%), Positives = 91/163 (55%), Gaps = 2/163 (1%) Frame = -1 Query: 664 RXKPFNCNLLYHDRLQINPELEKEIGAKFEEDLDAMLPKCDVVVINTPLTEKTRGMFNKE 485 R + F +LY+ R + PE EKE+GA+F L+ +L + D VV+ PLT++T+ M N+E Sbjct: 168 RARGFGMRILYYSRSR-KPEAEKELGAEFRS-LEDLLRESDFVVLAVPLTKETQYMINEE 225 Query: 484 KIAKMKKGVIIVNNARGAIMDTQAVADACSSGHIAGYGGDVWFPQPAPKDHPWRYMPNHA 305 ++ MKK I+VN ARG ++DT+A+ A G IAG G DV+ +P + + + N Sbjct: 226 RLRLMKKTAILVNIARGKVVDTKALMKALKEGWIAGAGLDVYEEEPYYNEELFS-LKNVV 284 Query: 304 MTPHISGTTIDAQLRYAAGVKDMLDRYFKGEEFP--VENYIVK 182 + PHI T A+ A V L + GE P V +VK Sbjct: 285 LAPHIGSATYGAREGMAELVARNLIAFKNGEVPPTLVNKEVVK 327
>SERA_METJA (Q58424) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (PGDH)| Length = 524 Score = 90.5 bits (223), Expect = 4e-18 Identities = 51/151 (33%), Positives = 84/151 (55%) Frame = -1 Query: 664 RXKPFNCNLLYHDRLQINPELEKEIGAKFEEDLDAMLPKCDVVVINTPLTEKTRGMFNKE 485 R K F N++ +D I E+ + +G + +D++ + + D + ++ PLT KTR + +E Sbjct: 157 RAKAFGMNIIGYDPY-IPKEVAESMGVELVDDINELCKRADFITLHVPLTPKTRHIIGRE 215 Query: 484 KIAKMKKGVIIVNNARGAIMDTQAVADACSSGHIAGYGGDVWFPQPAPKDHPWRYMPNHA 305 +IA MKK IIVN ARG ++D +A+ +A G I DV+ +P PKD+P + N Sbjct: 216 QIALMKKNAIIVNCARGGLIDEKALYEALKEGKIRAAALDVFEEEP-PKDNPLLTLDNVI 274 Query: 304 MTPHISGTTIDAQLRYAAGVKDMLDRYFKGE 212 TPH +T +AQ V + + + +GE Sbjct: 275 GTPHQGASTEEAQKAAGTIVAEQIKKVLRGE 305
>GYAR_PYRFU (Q8U3Y2) Glyoxylate reductase (EC 1.1.1.26) (Glycolate reductase)| Length = 336 Score = 90.5 bits (223), Expect = 4e-18 Identities = 55/151 (36%), Positives = 87/151 (57%) Frame = -1 Query: 664 RXKPFNCNLLYHDRLQINPELEKEIGAKFEEDLDAMLPKCDVVVINTPLTEKTRGMFNKE 485 R K FN +LY+ R + + EKE+GA++ L+ +L + D V++ PLT++T M N+E Sbjct: 168 RAKGFNMRILYYSRTR-KSQAEKELGAEYRP-LEEVLKESDFVILAVPLTKETMYMINEE 225 Query: 484 KIAKMKKGVIIVNNARGAIMDTQAVADACSSGHIAGYGGDVWFPQPAPKDHPWRYMPNHA 305 ++ MK I+VN ARG ++DT+A+ A G IAG G DV+ +P + + + N Sbjct: 226 RLKLMKPTAILVNIARGKVVDTKALIKALKEGWIAGAGLDVFEEEPYYNEELFS-LDNVV 284 Query: 304 MTPHISGTTIDAQLRYAAGVKDMLDRYFKGE 212 +TPHI T +A+ A V L + +GE Sbjct: 285 LTPHIGSATFEAREAMAELVARNLIAFKRGE 315
>GYAR_PYRHO (O58320) Glyoxylate reductase (EC 1.1.1.26) (Glycolate reductase)| Length = 334 Score = 89.4 bits (220), Expect = 9e-18 Identities = 54/151 (35%), Positives = 87/151 (57%) Frame = -1 Query: 664 RXKPFNCNLLYHDRLQINPELEKEIGAKFEEDLDAMLPKCDVVVINTPLTEKTRGMFNKE 485 R K FN +LY+ R + E+E+E+ A+F+ L+ +L + D VV+ PLT +T + N+E Sbjct: 168 RAKGFNMRILYYSRTR-KEEVERELNAEFKP-LEDLLRESDFVVLAVPLTRETYHLINEE 225 Query: 484 KIAKMKKGVIIVNNARGAIMDTQAVADACSSGHIAGYGGDVWFPQPAPKDHPWRYMPNHA 305 ++ MKK I++N ARG ++DT A+ A G IAG G DV+ +P + ++ + N Sbjct: 226 RLKLMKKTAILINIARGKVVDTNALVKALKEGWIAGAGLDVFEEEPYYNEELFK-LDNVV 284 Query: 304 MTPHISGTTIDAQLRYAAGVKDMLDRYFKGE 212 +TPHI + A+ A V L + +GE Sbjct: 285 LTPHIGSASFGAREGMAELVAKNLIAFKRGE 315
>GYAR_THELI (Q9C4M5) Glyoxylate reductase (EC 1.1.1.26) (Glycolate reductase)| Length = 331 Score = 88.2 bits (217), Expect = 2e-17 Identities = 51/151 (33%), Positives = 86/151 (56%) Frame = -1 Query: 664 RXKPFNCNLLYHDRLQINPELEKEIGAKFEEDLDAMLPKCDVVVINTPLTEKTRGMFNKE 485 R K F ++Y+ R + PE E+EIGA++ D + +L + D + ++ PLT++T M ++ Sbjct: 168 RAKGFGMKIIYYSRTR-KPEAEEEIGAEYV-DFETLLKESDFISLHVPLTKETYHMIGEK 225 Query: 484 KIAKMKKGVIIVNNARGAIMDTQAVADACSSGHIAGYGGDVWFPQPAPKDHPWRYMPNHA 305 ++ MK I++N +RGA++DT A+ A G IAG G DV+ +P + ++ + N Sbjct: 226 ELKLMKPNAILINTSRGAVVDTNALIKALKEGWIAGAGLDVFEEEPYYNEELFK-LKNVV 284 Query: 304 MTPHISGTTIDAQLRYAAGVKDMLDRYFKGE 212 + PHI T +A+ A V L + KGE Sbjct: 285 LAPHIGSATHEAREGMAELVAKNLIAFAKGE 315
>YGDH_SCHPO (O94574) Putative 2-hydroxyacid dehydrogenase C1773.17c (EC| 1.-.-.-) Length = 340 Score = 85.9 bits (211), Expect = 1e-16 Identities = 46/121 (38%), Positives = 65/121 (53%) Frame = -1 Query: 655 PFNCNLLYHDRLQINPELEKEIGAKFEEDLDAMLPKCDVVVINTPLTEKTRGMFNKEKIA 476 P C ++YH+R ++ E EK +GA F D +L DV+ IN PLT T + + ++ Sbjct: 180 PLGCEIVYHNRNRLEAEEEKRLGASFVS-FDELLSSSDVISINCPLTPATHDLISTKEFE 238 Query: 475 KMKKGVIIVNNARGAIMDTQAVADACSSGHIAGYGGDVWFPQPAPKDHPWRYMPNHAMTP 296 KMK GV I+N ARGAI++ A A SG +A G DV+ +P P W + P Sbjct: 239 KMKDGVYIINTARGAIINEDAFIKAIKSGKVARAGLDVFLNEPTPNKF-WLECDKVTIQP 297 Query: 295 H 293 H Sbjct: 298 H 298
>SERA_MYCTU (P0A544) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (PGDH)| Length = 528 Score = 85.5 bits (210), Expect = 1e-16 Identities = 48/138 (34%), Positives = 76/138 (55%) Frame = -1 Query: 616 INPELEKEIGAKFEEDLDAMLPKCDVVVINTPLTEKTRGMFNKEKIAKMKKGVIIVNNAR 437 ++P ++G + LD +L + D + ++ P T +T G+ +KE +AK K GVIIVN AR Sbjct: 174 VSPARAAQLGIELLS-LDDLLARADFISVHLPKTPETAGLIDKEALAKTKPGVIIVNAAR 232 Query: 436 GAIMDTQAVADACSSGHIAGYGGDVWFPQPAPKDHPWRYMPNHAMTPHISGTTIDAQLRY 257 G ++D A+ADA + GH+ G DV+ +P D P + +TPH+ +T +AQ R Sbjct: 233 GGLVDEAALADAITGGHVRAAGLDVFATEPC-TDSPLFELAQVVVTPHLGASTAEAQDRA 291 Query: 256 AAGVKDMLDRYFKGEEFP 203 V + + GE P Sbjct: 292 GTDVAESVRLALAGEFVP 309
>SERA_MYCBO (P0A545) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (PGDH)| Length = 528 Score = 85.5 bits (210), Expect = 1e-16 Identities = 48/138 (34%), Positives = 76/138 (55%) Frame = -1 Query: 616 INPELEKEIGAKFEEDLDAMLPKCDVVVINTPLTEKTRGMFNKEKIAKMKKGVIIVNNAR 437 ++P ++G + LD +L + D + ++ P T +T G+ +KE +AK K GVIIVN AR Sbjct: 174 VSPARAAQLGIELLS-LDDLLARADFISVHLPKTPETAGLIDKEALAKTKPGVIIVNAAR 232 Query: 436 GAIMDTQAVADACSSGHIAGYGGDVWFPQPAPKDHPWRYMPNHAMTPHISGTTIDAQLRY 257 G ++D A+ADA + GH+ G DV+ +P D P + +TPH+ +T +AQ R Sbjct: 233 GGLVDEAALADAITGGHVRAAGLDVFATEPC-TDSPLFELAQVVVTPHLGASTAEAQDRA 291 Query: 256 AAGVKDMLDRYFKGEEFP 203 V + + GE P Sbjct: 292 GTDVAESVRLALAGEFVP 309
>SERA_MYCLE (O33116) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (PGDH)| Length = 528 Score = 84.7 bits (208), Expect = 2e-16 Identities = 51/154 (33%), Positives = 81/154 (52%) Frame = -1 Query: 664 RXKPFNCNLLYHDRLQINPELEKEIGAKFEEDLDAMLPKCDVVVINTPLTEKTRGMFNKE 485 R F +++ +D + P ++G + D +L + D + ++ P T +T G+ +KE Sbjct: 159 RIAAFGAHVIAYDPY-VAPARAAQLGIELMS-FDDLLARADFISVHLPKTPETAGLIDKE 216 Query: 484 KIAKMKKGVIIVNNARGAIMDTQAVADACSSGHIAGYGGDVWFPQPAPKDHPWRYMPNHA 305 +AK K GVIIVN ARG ++D A+ADA SGH+ G DV+ +P D P + Sbjct: 217 ALAKTKPGVIIVNAARGGLVDEVALADAVRSGHVRAAGLDVFATEPC-TDSPLFELSQVV 275 Query: 304 MTPHISGTTIDAQLRYAAGVKDMLDRYFKGEEFP 203 +TPH+ +T +AQ R V + + GE P Sbjct: 276 VTPHLGASTAEAQDRAGTDVAESVRLALAGEFVP 309
>Y1556_HAEIN (P45250) Putative 2-hydroxyacid dehydrogenase HI1556 (EC 1.-.-.-)| Length = 315 Score = 84.0 bits (206), Expect = 4e-16 Identities = 41/118 (34%), Positives = 66/118 (55%), Gaps = 4/118 (3%) Frame = -1 Query: 565 DAMLPKCDVVVINTPLTEKTRGMFNKEKIAKMKKGVIIVNNARGAIMDTQAVADACSSGH 386 D +L + D+V ++ PLTE T+ + N E ++KMKKG ++N RG ++D A+ DA +GH Sbjct: 191 DEVLKQADIVTLHCPLTETTKDLINAETLSKMKKGAFLINTGRGPLIDELALVDALKTGH 250 Query: 385 IAGYGGDVWFPQPAPKDHPW----RYMPNHAMTPHISGTTIDAQLRYAAGVKDMLDRY 224 + G DV +P KD+P + MPN +TPHI+ + A V ++ + Sbjct: 251 LGGAALDVMVKEPPEKDNPLILAAKTMPNLIITPHIAWASDSAVTTLVGKVMQNIEEF 308
>SERA_METTH (O27051) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (PGDH)| Length = 525 Score = 82.4 bits (202), Expect = 1e-15 Identities = 52/150 (34%), Positives = 82/150 (54%) Frame = -1 Query: 664 RXKPFNCNLLYHDRLQINPELEKEIGAKFEEDLDAMLPKCDVVVINTPLTEKTRGMFNKE 485 R K F +++ +D I+ E +E+G DL+ +L + D+V I+ PLT +TR + +++ Sbjct: 159 RTKAFGMDIMVYDPY-ISKEAAEEMGVTVT-DLETLLRESDIVTIHVPLTPETRHLISED 216 Query: 484 KIAKMKKGVIIVNNARGAIMDTQAVADACSSGHIAGYGGDVWFPQPAPKDHPWRYMPNHA 305 + MK IVN ARG I+D A+ A G IAG DV+ +P P+ P + N Sbjct: 217 EFKLMKDTAFIVNCARGGIIDEDALYRALKDGEIAGAALDVFEEEP-PEGSPLLELENVV 275 Query: 304 MTPHISGTTIDAQLRYAAGVKDMLDRYFKG 215 +TPHI +T +AQ A V + + F+G Sbjct: 276 LTPHIGASTSEAQRDAAIIVANEIKTVFQG 305
>YEAA_SCHPO (O14075) Putative 2-hydroxyacid dehydrogenase UNK4.10 (EC 1.-.-.-)| Length = 334 Score = 82.0 bits (201), Expect = 1e-15 Identities = 51/142 (35%), Positives = 79/142 (55%), Gaps = 2/142 (1%) Frame = -1 Query: 664 RXKPFNCNLLYHDRLQINPELEKEIGAKFEEDLDAMLPKCDVVVINTPLTEKTRGMFNKE 485 R + F+ ++YH+R + PE E E GA+F D +L K DV+ +N PL TR + K Sbjct: 174 RARAFDMKIVYHNRTPL-PEEEAE-GAEFVS-FDDLLAKSDVLSLNLPLNAHTRHIIGKP 230 Query: 484 KIAKMKKGVIIVNNARGAIMDTQAVADACSSGHIAGYGGDVWFPQPAPKDHPWRYMPNH- 308 + KMK+G++IVN ARGA+MD A+ +A G + G DV+ + PK HP + N Sbjct: 231 EFQKMKRGIVIVNTARGAVMDEAALVEALDEGIVYSAGLDVF--EEEPKIHP-GLLENEK 287 Query: 307 -AMTPHISGTTIDAQLRYAAGV 245 + PH+ +++ Q + V Sbjct: 288 VILLPHLGTNSLETQYKMECAV 309
>TKRA_BACSU (O32264) Probable 2-ketogluconate reductase (EC 1.1.1.215) (2KR)| Length = 325 Score = 81.3 bits (199), Expect = 2e-15 Identities = 47/132 (35%), Positives = 74/132 (56%) Frame = -1 Query: 652 FNCNLLYHDRLQINPELEKEIGAKFEEDLDAMLPKCDVVVINTPLTEKTRGMFNKEKIAK 473 F+ +LYH+R + E E IG K+ E LD +L + D +++ TPLT++T M + + Sbjct: 171 FDMEVLYHNRHR-KQETEDSIGVKYAE-LDTLLEQSDFILLITPLTDETYHMIGEREFKL 228 Query: 472 MKKGVIIVNNARGAIMDTQAVADACSSGHIAGYGGDVWFPQPAPKDHPWRYMPNHAMTPH 293 MK I VN +RG +D +A+ A G I G G DV+ +P +D+P + N + PH Sbjct: 229 MKNSAIFVNISRGKTVDEKALIRALQEGWIRGAGLDVYEKEPVTQDNPLLQLDNVTLLPH 288 Query: 292 ISGTTIDAQLRY 257 I T A++R+ Sbjct: 289 IGSAT--AKVRF 298
>TKRA_ECOLI (P37666) 2-ketogluconate reductase (EC 1.1.1.215) (2KR)| (2-ketoaldonate reductase) Length = 324 Score = 79.7 bits (195), Expect = 7e-15 Identities = 50/147 (34%), Positives = 73/147 (49%) Frame = -1 Query: 652 FNCNLLYHDRLQINPELEKEIGAKFEEDLDAMLPKCDVVVINTPLTEKTRGMFNKEKIAK 473 FN +LY+ R + E E+ A++ DLD +L + D V + PLT++T +F E+ AK Sbjct: 168 FNMPILYNARRH-HKEAEERFNARYC-DLDTLLQESDFVCLILPLTDETHHLFGAEQFAK 225 Query: 472 MKKGVIIVNNARGAIMDTQAVADACSSGHIAGYGGDVWFPQPAPKDHPWRYMPNHAMTPH 293 MK I +N RG ++D A+ A G I G DV+ +P D P M N PH Sbjct: 226 MKSSAIFINAGRGPVVDENALIAALQKGEIHAAGLDVFEQEPLSVDSPLLSMANVVAVPH 285 Query: 292 ISGTTIDAQLRYAAGVKDMLDRYFKGE 212 I T + + AA D L +G+ Sbjct: 286 IGSATHETRYGMAACAVDNLIDALQGK 312
>TKRA_ECO57 (P58220) 2-ketogluconate reductase (EC 1.1.1.215) (2KR)| (2-ketoaldonate reductase) Length = 324 Score = 79.7 bits (195), Expect = 7e-15 Identities = 50/147 (34%), Positives = 73/147 (49%) Frame = -1 Query: 652 FNCNLLYHDRLQINPELEKEIGAKFEEDLDAMLPKCDVVVINTPLTEKTRGMFNKEKIAK 473 FN +LY+ R + E E+ A++ DLD +L + D V + PLT++T +F E+ AK Sbjct: 168 FNMPILYNARRH-HKEAEERFNARYC-DLDTLLQESDFVCLILPLTDETHHLFGAEQFAK 225 Query: 472 MKKGVIIVNNARGAIMDTQAVADACSSGHIAGYGGDVWFPQPAPKDHPWRYMPNHAMTPH 293 MK I +N RG ++D A+ A G I G DV+ +P D P M N PH Sbjct: 226 MKSSAIFINAGRGPVVDENALIAALQKGEIHAAGLDVFEQEPLSVDSPLLSMANVVAVPH 285 Query: 292 ISGTTIDAQLRYAAGVKDMLDRYFKGE 212 I T + + AA D L +G+ Sbjct: 286 IGSATHETRYGMAACAVDNLIDALQGK 312
>YN14_YEAST (P53839) Putative 2-hydroxyacid dehydrogenase YNL274C (EC 1.-.-.-)| Length = 350 Score = 79.3 bits (194), Expect = 9e-15 Identities = 46/107 (42%), Positives = 63/107 (58%), Gaps = 1/107 (0%) Frame = -1 Query: 664 RXKPFNC-NLLYHDRLQINPELEKEIGAKFEEDLDAMLPKCDVVVINTPLTEKTRGMFNK 488 R KPF N +YH+R Q+ E +E G ++ + L + D+V +N PL T + N Sbjct: 181 RLKPFGFENFIYHNRHQLPSE--EEHGCEYV-GFEEFLKRSDIVSVNVPLNHNTHHLINA 237 Query: 487 EKIAKMKKGVIIVNNARGAIMDTQAVADACSSGHIAGYGGDVWFPQP 347 E I KMK GV+IVN ARGA++D QA+ DA SG I G DV+ +P Sbjct: 238 ETIEKMKDGVVIVNTARGAVIDEQAMTDALRSGKIRSAGLDVFEYEP 284
>SERA_BOVIN (Q5EAD2) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (3-PGDH)| Length = 532 Score = 77.8 bits (190), Expect = 3e-14 Identities = 47/135 (34%), Positives = 71/135 (52%) Frame = -1 Query: 664 RXKPFNCNLLYHDRLQINPELEKEIGAKFEEDLDAMLPKCDVVVINTPLTEKTRGMFNKE 485 R + F + +D + I+PE+ G + + L+ + P CD + ++TPL T G+ N Sbjct: 162 RMQSFGMKTIGYDPI-ISPEVSASFGVQ-QLPLEQIWPLCDFITVHTPLLPSTTGLLNDS 219 Query: 484 KIAKMKKGVIIVNNARGAIMDTQAVADACSSGHIAGYGGDVWFPQPAPKDHPWRYMPNHA 305 A+ KKGV +VN ARG I+D A+ A SG AG DV+ +P P+D N Sbjct: 220 TFAQCKKGVCVVNCARGGIVDEGALLRALQSGQCAGAALDVFTEEP-PRDRALVNHENVI 278 Query: 304 MTPHISGTTIDAQLR 260 PH+ +T +AQ R Sbjct: 279 SCPHLGASTKEAQSR 293
>TKRA_ENTAG (P58000) 2-ketogluconate reductase (EC 1.1.1.215) (2KR)| (2-ketoaldonate reductase) Length = 323 Score = 77.8 bits (190), Expect = 3e-14 Identities = 48/140 (34%), Positives = 71/140 (50%) Frame = -1 Query: 652 FNCNLLYHDRLQINPELEKEIGAKFEEDLDAMLPKCDVVVINTPLTEKTRGMFNKEKIAK 473 F +LY+ R + E E A++ DLD +L + D + I+ PLTE+T M +E++AK Sbjct: 167 FGMPILYNARKH-HEEAESRFNAQYC-DLDTLLRESDFLCISLPLTEQTHHMIGREQLAK 224 Query: 472 MKKGVIIVNNARGAIMDTQAVADACSSGHIAGYGGDVWFPQPAPKDHPWRYMPNHAMTPH 293 MK I++N RG ++D QA+ A I G DV+ +P P D +PN PH Sbjct: 225 MKPSAILINAGRGPVVDEQALIAALKDKTIHAAGLDVFEQEPLPVDSELLTLPNVVALPH 284 Query: 292 ISGTTIDAQLRYAAGVKDML 233 I T + + A D L Sbjct: 285 IGSATHETRYGMARDAVDNL 304
>DHGY_HYPME (P36234) Glycerate dehydrogenase (EC 1.1.1.29) (NADH-dependent| hydroxypyruvate reductase) (HPR) (GDH) (Hydroxypyruvate dehydrogenase) (Glyoxylate reductase) Length = 321 Score = 77.8 bits (190), Expect = 3e-14 Identities = 46/152 (30%), Positives = 75/152 (49%) Frame = -1 Query: 664 RXKPFNCNLLYHDRLQINPELEKEIGAKFEEDLDAMLPKCDVVVINTPLTEKTRGMFNKE 485 R + F+ ++ Y D + + E A F + LD++L +N P T +TR FNK Sbjct: 165 RAQGFDMDIDYFDTHRASSSDEASYQATFHDSLDSLLSVSQFFSLNAPSTPETRYFFNKA 224 Query: 484 KIAKMKKGVIIVNNARGAIMDTQAVADACSSGHIAGYGGDVWFPQPAPKDHPWRYMPNHA 305 I + +G I+VN ARG ++D + V A +G +A G DV+ +P + + +PN Sbjct: 225 TIKSLPQGAIVVNTARGDLVDNELVVAALEAGRLAYAGFDVFAGEPNINE-GYYDLPNTF 283 Query: 304 MTPHISGTTIDAQLRYAAGVKDMLDRYFKGEE 209 + PHI A+ A D++D F G + Sbjct: 284 LFPHIGSAATQAREDMAHQANDLIDALFGGAD 315
>SERA_HAEIN (P43885) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (PGDH)| Length = 410 Score = 77.4 bits (189), Expect = 4e-14 Identities = 41/111 (36%), Positives = 63/111 (56%), Gaps = 4/111 (3%) Frame = -1 Query: 586 AKFEEDLDAMLPKCDVVVINTPLTEKTRGMFNKEKIAKMKKGVIIVNNARGAIMDTQAVA 407 AK L+ +L CDVV ++ P T+ + N +IA++K+G I++N ARG ++D A+A Sbjct: 192 AKQVRSLEELLSSCDVVSLHVPELPSTKNLMNVARIAQLKQGAILINAARGTVVDIDALA 251 Query: 406 DACSSGHIAGYGGDVWFPQPAPKDH----PWRYMPNHAMTPHISGTTIDAQ 266 A G + G DV+ +PA + P R N +TPHI G+T +AQ Sbjct: 252 QALKDGKLQGAAIDVFPVEPASINEEFISPLREFDNVILTPHIGGSTAEAQ 302
>SERA_MACFA (Q60HD7) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (3-PGDH)| Length = 532 Score = 76.6 bits (187), Expect = 6e-14 Identities = 47/135 (34%), Positives = 71/135 (52%) Frame = -1 Query: 664 RXKPFNCNLLYHDRLQINPELEKEIGAKFEEDLDAMLPKCDVVVINTPLTEKTRGMFNKE 485 R + F + +D + I+PE+ G + + L+ + P CD + ++TPL T G+ N Sbjct: 162 RMQSFGMKTIGYDPI-ISPEVSASFGVQ-QLPLEEIWPLCDFITVHTPLLPSTTGLLNDN 219 Query: 484 KIAKMKKGVIIVNNARGAIMDTQAVADACSSGHIAGYGGDVWFPQPAPKDHPWRYMPNHA 305 A+ KKGV +VN ARG I+D A+ A SG AG DV+ +P P+D N Sbjct: 220 TFAQCKKGVRVVNCARGGIVDEGALLRALQSGQCAGAALDVFTEEP-PRDRALVDHENVI 278 Query: 304 MTPHISGTTIDAQLR 260 PH+ +T +AQ R Sbjct: 279 SCPHLGASTKEAQSR 293
>SERA_HUMAN (O43175) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (3-PGDH)| Length = 532 Score = 76.6 bits (187), Expect = 6e-14 Identities = 47/135 (34%), Positives = 71/135 (52%) Frame = -1 Query: 664 RXKPFNCNLLYHDRLQINPELEKEIGAKFEEDLDAMLPKCDVVVINTPLTEKTRGMFNKE 485 R + F + +D + I+PE+ G + + L+ + P CD + ++TPL T G+ N Sbjct: 162 RMQSFGMKTIGYDPI-ISPEVSASFGVQ-QLPLEEIWPLCDFITVHTPLLPSTTGLLNDN 219 Query: 484 KIAKMKKGVIIVNNARGAIMDTQAVADACSSGHIAGYGGDVWFPQPAPKDHPWRYMPNHA 305 A+ KKGV +VN ARG I+D A+ A SG AG DV+ +P P+D N Sbjct: 220 TFAQCKKGVRVVNCARGGIVDEGALLRALQSGQCAGAALDVFTEEP-PRDRALVDHENVI 278 Query: 304 MTPHISGTTIDAQLR 260 PH+ +T +AQ R Sbjct: 279 SCPHLGASTKEAQSR 293
>SERA_RAT (O08651) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (3-PGDH)| Length = 532 Score = 75.9 bits (185), Expect = 1e-13 Identities = 47/135 (34%), Positives = 71/135 (52%) Frame = -1 Query: 664 RXKPFNCNLLYHDRLQINPELEKEIGAKFEEDLDAMLPKCDVVVINTPLTEKTRGMFNKE 485 R + F + +D + I+PE+ G + + L+ + P CD + ++TPL T G+ N Sbjct: 162 RMQAFGMKTVGYDPI-ISPEVAASFGVQ-QLPLEEIWPLCDFITVHTPLLPSTTGLLNDS 219 Query: 484 KIAKMKKGVIIVNNARGAIMDTQAVADACSSGHIAGYGGDVWFPQPAPKDHPWRYMPNHA 305 A+ KKGV +VN ARG I+D A+ A SG AG DV+ +P P+D N Sbjct: 220 TFAQCKKGVRVVNCARGGIVDEGALLRALQSGQCAGAALDVFTEEP-PRDRALVDHENVI 278 Query: 304 MTPHISGTTIDAQLR 260 PH+ +T +AQ R Sbjct: 279 SCPHLGASTKEAQSR 293
>SERA_MOUSE (Q61753) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (3-PGDH)| (A10) Length = 532 Score = 75.9 bits (185), Expect = 1e-13 Identities = 47/135 (34%), Positives = 71/135 (52%) Frame = -1 Query: 664 RXKPFNCNLLYHDRLQINPELEKEIGAKFEEDLDAMLPKCDVVVINTPLTEKTRGMFNKE 485 R + F + +D + I+PE+ G + + L+ + P CD + ++TPL T G+ N Sbjct: 162 RMQSFGMKTVGYDPI-ISPEVAASFGVQ-QLPLEEIWPLCDFITVHTPLLPSTTGLLNDS 219 Query: 484 KIAKMKKGVIIVNNARGAIMDTQAVADACSSGHIAGYGGDVWFPQPAPKDHPWRYMPNHA 305 A+ KKGV +VN ARG I+D A+ A SG AG DV+ +P P+D N Sbjct: 220 TFAQCKKGVRVVNCARGGIVDEGALLRALQSGQCAGAALDVFTEEP-PRDRALVDHENVI 278 Query: 304 MTPHISGTTIDAQLR 260 PH+ +T +AQ R Sbjct: 279 SCPHLGASTKEAQSR 293
>SERA_SCHPO (P87228) Putative D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95)| (3-PGDH) Length = 466 Score = 75.5 bits (184), Expect = 1e-13 Identities = 51/153 (33%), Positives = 81/153 (52%), Gaps = 13/153 (8%) Frame = -1 Query: 643 NLLYHDRLQINPELEKEIG-AKFEEDLDAMLPKCDVVVINTPLTEKTRGMFNKEKIAKMK 467 +++Y+D L I P +G AK L +L + D V ++ P + +T+ M + ++ A MK Sbjct: 220 HVVYYDILPIMP-----LGSAKQLSSLPELLHRADFVSLHVPASPETKNMISSKEFAAMK 274 Query: 466 KGVIIVNNARGAIMDTQAVADACSSGHIAGYGGDVWFPQPA--PKD------HPW----R 323 +G ++N +RG ++D A+ DA SG IAG DV+ +PA KD + W Sbjct: 275 EGSYLINASRGTVVDIPALVDASKSGKIAGAAIDVYPSEPAGNGKDKFVDSLNSWTSELT 334 Query: 322 YMPNHAMTPHISGTTIDAQLRYAAGVKDMLDRY 224 + N +TPHI G+T +AQ V + L RY Sbjct: 335 HCKNIILTPHIGGSTEEAQYNIGIEVSEALTRY 367
>GRHPR_HUMAN (Q9UBQ7) Glyoxylate reductase/hydroxypyruvate reductase (EC| 1.1.1.79) Length = 328 Score = 75.1 bits (183), Expect = 2e-13 Identities = 47/156 (30%), Positives = 73/156 (46%) Frame = -1 Query: 664 RXKPFNCNLLYHDRLQINPELEKEIGAKFEEDLDAMLPKCDVVVINTPLTEKTRGMFNKE 485 R KPF + Q PE E A+F + + + D +V+ LT T G+ NK+ Sbjct: 171 RLKPFGVQRFLYTGRQPRPEEAAEFQAEFVSTPE-LAAQSDFIVVACSLTPATEGLCNKD 229 Query: 484 KIAKMKKGVIIVNNARGAIMDTQAVADACSSGHIAGYGGDVWFPQPAPKDHPWRYMPNHA 305 KMK+ + +N +RG +++ + A +SG IA G DV P+P P +HP + N Sbjct: 230 FFQKMKETAVFINISRGDVVNQDDLYQALASGKIAAAGLDVTSPEPLPTNHPLLTLKNCV 289 Query: 304 MTPHISGTTIDAQLRYAAGVKDMLDRYFKGEEFPVE 197 + PHI T + + + L +GE P E Sbjct: 290 ILPHIGSATHRTRNTMSLLAANNLLAGLRGEPMPSE 325
>GRHPR_MOUSE (Q91Z53) Glyoxylate reductase/hydroxypyruvate reductase (EC| 1.1.1.79) Length = 328 Score = 74.7 bits (182), Expect = 2e-13 Identities = 46/156 (29%), Positives = 73/156 (46%) Frame = -1 Query: 664 RXKPFNCNLLYHDRLQINPELEKEIGAKFEEDLDAMLPKCDVVVINTPLTEKTRGMFNKE 485 R KPF + Q P+ E A+F + + + D +V++ LT T G+ +K+ Sbjct: 171 RLKPFGVQRFLYTGRQPRPQEAAEFQAEFVP-IAQLAAESDFIVVSCSLTPDTMGLCSKD 229 Query: 484 KIAKMKKGVIIVNNARGAIMDTQAVADACSSGHIAGYGGDVWFPQPAPKDHPWRYMPNHA 305 KMK I +N +RG +++ + + A +SG IA G DV P+P P HP + N Sbjct: 230 FFQKMKNTAIFINISRGDVVNQEDLYQALASGQIAAAGLDVTTPEPLPPSHPLLTLKNCV 289 Query: 304 MTPHISGTTIDAQLRYAAGVKDMLDRYFKGEEFPVE 197 + PHI T + + + L +GE P E Sbjct: 290 ILPHIGSATYKTRNTMSLLAANNLLAGLRGEAMPSE 325
>SERA_ARATH (O04130) D-3-phosphoglycerate dehydrogenase, chloroplast precursor| (EC 1.1.1.95) (3-PGDH) Length = 624 Score = 73.9 bits (180), Expect = 4e-13 Identities = 41/118 (34%), Positives = 63/118 (53%) Frame = -1 Query: 565 DAMLPKCDVVVINTPLTEKTRGMFNKEKIAKMKKGVIIVNNARGAIMDTQAVADACSSGH 386 D + D V ++ PLT T+ +FN E +KMKKGV ++N ARG ++D A+ A +G Sbjct: 270 DQAISTADFVSLHMPLTPATKKVFNDETFSKMKKGVRLINVARGGVIDEDALVRALDAGI 329 Query: 385 IAGYGGDVWFPQPAPKDHPWRYMPNHAMTPHISGTTIDAQLRYAAGVKDMLDRYFKGE 212 +A DV+ +P KD N +TPH+ +T +AQ A + + + KGE Sbjct: 330 VAQAALDVFCEEPPSKDSRLIQHENVTVTPHLGASTKEAQEGVAIEIAEAVAGALKGE 387
>DHGY_METEX (Q59516) Glycerate dehydrogenase (EC 1.1.1.29) (NADH-dependent| hydroxypyruvate reductase) (HPR) (GDH) (Hydroxypyruvate dehydrogenase) (Glyoxylate reductase) (HPR-A) Length = 313 Score = 73.6 bits (179), Expect = 5e-13 Identities = 41/123 (33%), Positives = 68/123 (55%), Gaps = 3/123 (2%) Frame = -1 Query: 571 DLDAMLPKCDVVVINTPLTEKTRGMFNKEKIAKMKKGVIIVNNARGAIMDTQAVADACSS 392 DL+ +L + DV+ ++ PLT T+ M E++ KMK+ I++N ARG ++D A+ A Sbjct: 185 DLETILTQSDVITLHVPLTPDTKNMIGAEQLKKMKRSAILINTARGGLVDEAALLQALKD 244 Query: 391 GHIAGYGGDVWFPQPAPKDHPW---RYMPNHAMTPHISGTTIDAQLRYAAGVKDMLDRYF 221 G I G G DV +P PKD +PN +TPH++ + +A A + D ++ + Sbjct: 245 GTIGGAGFDVVAQEP-PKDGNILCDADLPNLIVTPHVAWASKEAMQILADQLVDNVEAFV 303 Query: 220 KGE 212 G+ Sbjct: 304 AGK 306
>Y2355_CORGL (P0C1E8) Hypothetical protein Cgl2355/cg2587 (EC 1.-.-.-)| Length = 304 Score = 72.8 bits (177), Expect = 9e-13 Identities = 42/124 (33%), Positives = 67/124 (54%), Gaps = 2/124 (1%) Frame = -1 Query: 550 KCDVVVINTPLTEKTRGMFNKEKIAKMKKGVIIVNNARGAIMDTQAVADACSSGHIAGYG 371 + DV V+ PLT+ T + N E + KMK ++VN RG +++T + DA ++G IAG Sbjct: 180 EADVFVLILPLTDATYQIVNAETLGKMKPSAVVVNVGRGPLINTDDLVDALNNGTIAGAA 239 Query: 370 GDVWFPQPAPKDHPWRYMPNHAMTPHISGTTIDAQLRYAAGVKDM--LDRYFKGEEFPVE 197 DV P+P P HP M N +TPH + T + ++R G + ++ + GE+ E Sbjct: 240 LDVTDPEPLPDSHPLWEMDNVVITPHTANT--NERIRALTGELTLRNIELFEAGEQMATE 297 Query: 196 NYIV 185 +V Sbjct: 298 VDVV 301
>SERA_PONPY (Q5R7M2) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (3-PGDH)| Length = 532 Score = 72.8 bits (177), Expect = 9e-13 Identities = 43/119 (36%), Positives = 63/119 (52%) Frame = -1 Query: 616 INPELEKEIGAKFEEDLDAMLPKCDVVVINTPLTEKTRGMFNKEKIAKMKKGVIIVNNAR 437 I+PE+ G + + L+ + P CD + ++TPL T G+ N A+ KKGV +VN AR Sbjct: 177 ISPEVSASFGVQ-QLPLEEIWPLCDFITVHTPLLPSTTGLLNDNTFAQCKKGVRVVNCAR 235 Query: 436 GAIMDTQAVADACSSGHIAGYGGDVWFPQPAPKDHPWRYMPNHAMTPHISGTTIDAQLR 260 G I+D A+ A SG AG DV+ +P P+ N PH+ +T +AQ R Sbjct: 236 GGIVDEGALLRALQSGQCAGAALDVFTEEP-PRGRALVDHENVISCPHLGASTKEAQSR 293
>YPRB2_CORML (P0C1E9) Hypothetical protein in proB 3'region (EC 1.-.-.-)| Length = 304 Score = 72.4 bits (176), Expect = 1e-12 Identities = 42/124 (33%), Positives = 67/124 (54%), Gaps = 2/124 (1%) Frame = -1 Query: 550 KCDVVVINTPLTEKTRGMFNKEKIAKMKKGVIIVNNARGAIMDTQAVADACSSGHIAGYG 371 + DV V+ PLT+ T + N E + KMK ++VN RG +++T + DA ++G IAG Sbjct: 180 EADVFVLILPLTDATYQIVNAETLGKMKPSAVLVNVGRGPLINTDDLVDALNNGTIAGAA 239 Query: 370 GDVWFPQPAPKDHPWRYMPNHAMTPHISGTTIDAQLRYAAGVKDM--LDRYFKGEEFPVE 197 DV P+P P HP M N +TPH + T + ++R G + ++ + GE+ E Sbjct: 240 LDVTDPEPLPDSHPLWEMDNVVITPHTANT--NERIRALTGELTLRNIELFEAGEQMATE 297 Query: 196 NYIV 185 +V Sbjct: 298 VDVV 301
>DDH_ZYMMO (P30799) 2-hydroxyacid dehydrogenase homolog (EC 1.1.1.-)| Length = 331 Score = 72.0 bits (175), Expect = 1e-12 Identities = 32/85 (37%), Positives = 55/85 (64%) Frame = -1 Query: 613 NPELEKEIGAKFEEDLDAMLPKCDVVVINTPLTEKTRGMFNKEKIAKMKKGVIIVNNARG 434 +PEL K++G +F LD ++ D++ ++ PLT + M N+E +A+ KKG +VN +RG Sbjct: 179 DPELAKKVGFRFTS-LDEVIETSDIISLHCPLTPENHHMINEETLARAKKGFYLVNTSRG 237 Query: 433 AIMDTQAVADACSSGHIAGYGGDVW 359 ++DT+AV + + H+ GY DV+ Sbjct: 238 GLVDTKAVIKSLKAKHLGGYAADVY 262
>SERA_SHIFL (P0A9T3) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (PGDH)| Length = 409 Score = 70.9 bits (172), Expect = 3e-12 Identities = 40/121 (33%), Positives = 64/121 (52%), Gaps = 4/121 (3%) Frame = -1 Query: 574 EDLDAMLPKCDVVVINTPLTEKTRGMFNKEKIAKMKKGVIIVNNARGAIMDTQAVADACS 395 + L +L DVV ++ P T+ M ++I+ MK G +++N +RG ++D A+ DA + Sbjct: 194 QHLSDLLNMSDVVSLHVPENPSTKNMMGAKEISLMKPGSLLINASRGTVVDIPALCDALA 253 Query: 394 SGHIAGYGGDVWFPQPAPKDHPWR----YMPNHAMTPHISGTTIDAQLRYAAGVKDMLDR 227 S H+AG DV+ +PA P+ N +TPHI G+T +AQ V L + Sbjct: 254 SKHLAGAAIDVFPTEPATNSDPFTSPLCEFDNVLLTPHIGGSTQEAQENIGLEVAGKLIK 313 Query: 226 Y 224 Y Sbjct: 314 Y 314
>SERA_ECOLI (P0A9T0) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (PGDH)| Length = 409 Score = 70.9 bits (172), Expect = 3e-12 Identities = 40/121 (33%), Positives = 64/121 (52%), Gaps = 4/121 (3%) Frame = -1 Query: 574 EDLDAMLPKCDVVVINTPLTEKTRGMFNKEKIAKMKKGVIIVNNARGAIMDTQAVADACS 395 + L +L DVV ++ P T+ M ++I+ MK G +++N +RG ++D A+ DA + Sbjct: 194 QHLSDLLNMSDVVSLHVPENPSTKNMMGAKEISLMKPGSLLINASRGTVVDIPALCDALA 253 Query: 394 SGHIAGYGGDVWFPQPAPKDHPWR----YMPNHAMTPHISGTTIDAQLRYAAGVKDMLDR 227 S H+AG DV+ +PA P+ N +TPHI G+T +AQ V L + Sbjct: 254 SKHLAGAAIDVFPTEPATNSDPFTSPLCEFDNVLLTPHIGGSTQEAQENIGLEVAGKLIK 313 Query: 226 Y 224 Y Sbjct: 314 Y 314
>SERA_ECOL6 (P0A9T1) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (PGDH)| Length = 409 Score = 70.9 bits (172), Expect = 3e-12 Identities = 40/121 (33%), Positives = 64/121 (52%), Gaps = 4/121 (3%) Frame = -1 Query: 574 EDLDAMLPKCDVVVINTPLTEKTRGMFNKEKIAKMKKGVIIVNNARGAIMDTQAVADACS 395 + L +L DVV ++ P T+ M ++I+ MK G +++N +RG ++D A+ DA + Sbjct: 194 QHLSDLLNMSDVVSLHVPENPSTKNMMGAKEISLMKPGSLLINASRGTVVDIPALCDALA 253 Query: 394 SGHIAGYGGDVWFPQPAPKDHPWR----YMPNHAMTPHISGTTIDAQLRYAAGVKDMLDR 227 S H+AG DV+ +PA P+ N +TPHI G+T +AQ V L + Sbjct: 254 SKHLAGAAIDVFPTEPATNSDPFTSPLCEFDNVLLTPHIGGSTQEAQENIGLEVAGKLIK 313 Query: 226 Y 224 Y Sbjct: 314 Y 314
>SERA_ECO57 (P0A9T2) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (PGDH)| Length = 409 Score = 70.9 bits (172), Expect = 3e-12 Identities = 40/121 (33%), Positives = 64/121 (52%), Gaps = 4/121 (3%) Frame = -1 Query: 574 EDLDAMLPKCDVVVINTPLTEKTRGMFNKEKIAKMKKGVIIVNNARGAIMDTQAVADACS 395 + L +L DVV ++ P T+ M ++I+ MK G +++N +RG ++D A+ DA + Sbjct: 194 QHLSDLLNMSDVVSLHVPENPSTKNMMGAKEISLMKPGSLLINASRGTVVDIPALCDALA 253 Query: 394 SGHIAGYGGDVWFPQPAPKDHPWR----YMPNHAMTPHISGTTIDAQLRYAAGVKDMLDR 227 S H+AG DV+ +PA P+ N +TPHI G+T +AQ V L + Sbjct: 254 SKHLAGAAIDVFPTEPATNSDPFTSPLCEFDNVLLTPHIGGSTQEAQENIGLEVAGKLIK 313 Query: 226 Y 224 Y Sbjct: 314 Y 314
>SERA_SYNY3 (P73821) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (PGDH)| Length = 554 Score = 70.5 bits (171), Expect = 4e-12 Identities = 44/142 (30%), Positives = 71/142 (50%) Frame = -1 Query: 658 KPFNCNLLYHDRLQINPELEKEIGAKFEEDLDAMLPKCDVVVINTPLTEKTRGMFNKEKI 479 K LL +D I+ E +IG DLD + + D + ++ P T +T + N E + Sbjct: 187 KAMGMKLLAYDPF-ISQERADQIGCTLV-DLDLLFSEADFITLHIPKTPETANLINAETL 244 Query: 478 AKMKKGVIIVNNARGAIMDTQAVADACSSGHIAGYGGDVWFPQPAPKDHPWRYMPNHAMT 299 AKMK I+N +RG I+D +A+ A + I G DV+ +P + R N +T Sbjct: 245 AKMKPTARIINCSRGGIIDEEALVTAIETAQIGGAALDVFAQEPLGESR-LREFSNVILT 303 Query: 298 PHISGTTIDAQLRYAAGVKDML 233 PH+ +T +AQ+ A V + + Sbjct: 304 PHLGASTEEAQVNVAVDVAEQI 325
>DDH_HAEIN (P44501) 2-hydroxyacid dehydrogenase homolog (EC 1.1.1.-)| Length = 331 Score = 68.2 bits (165), Expect = 2e-11 Identities = 40/100 (40%), Positives = 59/100 (59%) Frame = -1 Query: 658 KPFNCNLLYHDRLQINPELEKEIGAKFEEDLDAMLPKCDVVVINTPLTEKTRGMFNKEKI 479 K F N+L +D + NP +E E+G ++ E LD + K V+ ++ P T + + N E Sbjct: 164 KGFGMNILAYDPFK-NPVVE-ELGGQYVE-LDELYAKSHVITLHCPATPENYHLLNCEAF 220 Query: 478 AKMKKGVIIVNNARGAIMDTQAVADACSSGHIAGYGGDVW 359 AKMK GV+IVN +RG+++DTQA DA I G DV+ Sbjct: 221 AKMKDGVMIVNTSRGSLIDTQAAIDALKQRKIGALGMDVY 260
>SERA_YEAST (P40054) D-3-phosphoglycerate dehydrogenase 1 (EC 1.1.1.95) (3-PGDH| 1) Length = 469 Score = 67.0 bits (162), Expect = 5e-11 Identities = 40/127 (31%), Positives = 62/127 (48%), Gaps = 12/127 (9%) Frame = -1 Query: 568 LDAMLPKCDVVVINTPLTEKTRGMFNKEKIAKMKKGVIIVNNARGAIMDTQAVADACSSG 389 LD +L K D V ++ P T +T M + + A MK G ++N +RG ++D ++ A + Sbjct: 244 LDELLNKSDFVTLHVPATPETEKMLSAPQFAAMKDGAYVINASRGTVVDIPSLIQAVKAN 303 Query: 388 HIAGYGGDVWFPQPAPKD--------HPWR----YMPNHAMTPHISGTTIDAQLRYAAGV 245 IAG DV+ +PA + W +PN +TPHI G+T +AQ V Sbjct: 304 KIAGAALDVYPHEPAKNGEGSFNDELNSWTSELVSLPNIILTPHIGGSTEEAQSSIGIEV 363 Query: 244 KDMLDRY 224 L +Y Sbjct: 364 ATALSKY 370
>SER33_YEAST (P40510) D-3-phosphoglycerate dehydrogenase 2 (EC 1.1.1.95) (3-PGDH| 2) Length = 469 Score = 67.0 bits (162), Expect = 5e-11 Identities = 40/127 (31%), Positives = 62/127 (48%), Gaps = 12/127 (9%) Frame = -1 Query: 568 LDAMLPKCDVVVINTPLTEKTRGMFNKEKIAKMKKGVIIVNNARGAIMDTQAVADACSSG 389 LD +L K D V ++ P T +T M + + A MK G ++N +RG ++D ++ A + Sbjct: 244 LDELLNKSDFVTLHVPATPETEKMLSAPQFAAMKDGAYVINASRGTVVDIPSLIQAVKAN 303 Query: 388 HIAGYGGDVWFPQPAPKD--------HPWR----YMPNHAMTPHISGTTIDAQLRYAAGV 245 IAG DV+ +PA + W +PN +TPHI G+T +AQ V Sbjct: 304 KIAGAALDVYPHEPAKNGEGSFNDELNSWTSELVSLPNIILTPHIGGSTEEAQSSIGIEV 363 Query: 244 KDMLDRY 224 L +Y Sbjct: 364 ATALSKY 370
>VANH_ENTFA (Q47748) D-specific alpha-keto acid dehydrogenase (EC 1.1.1.-)| (Vancomycin B-type resistance protein vanHB) Length = 323 Score = 65.1 bits (157), Expect = 2e-10 Identities = 42/137 (30%), Positives = 70/137 (51%), Gaps = 13/137 (9%) Frame = -1 Query: 664 RXKPFNCNLLYHDRLQINPELEKEIGAKFEEDLDAMLPKCDVVVINTPLTEKTRGMFNKE 485 R + F C +L +D ++I A + + LD +L D+V ++ PL TR + + Sbjct: 165 RLRGFGCRVLAYDN-------SRKIEADYVQ-LDELLKNSDIVTLHVPLCADTRHLIGQR 216 Query: 484 KIAKMKKGVIIVNNARGAIMDTQAVADACSSGHIAGYGGDVW-------FPQPAPK--DH 332 +I +MK+G ++N RGA++DT ++ +A SG + G DV + + K DH Sbjct: 217 QIGEMKQGAFLINTGRGALVDTGSLVEALGSGKLGGAALDVLEGEDQFVYTDCSQKVLDH 276 Query: 331 PW----RYMPNHAMTPH 293 P+ MPN +TPH Sbjct: 277 PFLSQLLRMPNVIITPH 293
>LDHD_LACDE (P26297) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific| D-2-hydroxyacid dehydrogenase) Length = 332 Score = 64.7 bits (156), Expect = 2e-10 Identities = 47/143 (32%), Positives = 69/143 (48%), Gaps = 15/143 (10%) Frame = -1 Query: 652 FNCNLLYHDRLQINPELEKEIGAKFEEDLDAMLPKCDVVVINTPLTEKTRGMFNKEKIAK 473 F ++ +D + NPELEK+ + + LD + + DV+ ++ P M N + IAK Sbjct: 167 FGAKVIAYDIFR-NPELEKK--GYYVDSLDDLYKQADVISLHVPDVPANVHMINDKSIAK 223 Query: 472 MKKGVIIVNNARGAIMDTQAVADACSSGHIAGYGGDVW---------------FPQPAPK 338 MK+ V+IVN +RG ++DT AV SG + GY DV+ FP Sbjct: 224 MKQDVVIVNVSRGPLVDTDAVIRGLDSGKVFGYAMDVYEGEVGVFNEDREGKEFPDARLA 283 Query: 337 DHPWRYMPNHAMTPHISGTTIDA 269 D R PN +TPH + T A Sbjct: 284 DLIAR--PNVLVTPHTAFYTTHA 304
>LDHD_LEUMC (P51011) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific| D-2-hydroxyacid dehydrogenase) Length = 331 Score = 63.5 bits (153), Expect = 5e-10 Identities = 47/163 (28%), Positives = 74/163 (45%), Gaps = 13/163 (7%) Frame = -1 Query: 658 KPFNCNLLYHDRLQINPELEKEIGAKFEEDLDAMLPKCDVVVINTPLTEKTRGMFNKEKI 479 K F ++ +D+ N EL+ E + + LD + + D + + P + + N + I Sbjct: 165 KGFGAKVIAYDKYP-NAELQAE--GLYVDTLDELYAQADAISLYVPGVPENHHLINADAI 221 Query: 478 AKMKKGVIIVNNARGAIMDTQAVADACSSGHIAGYGGDVWFPQ-------------PAPK 338 AKMK GV+I+N ARG +MD A+ D +SG I+ +G DV+ + P K Sbjct: 222 AKMKDGVVIMNAARGNLMDIDAIIDGLNSGKISDFGMDVYENEVACSMKIGLVKNSPDAK 281 Query: 337 DHPWRYMPNHAMTPHISGTTIDAQLRYAAGVKDMLDRYFKGEE 209 N +TPH + T A L D + KGE+ Sbjct: 282 IADLIARENVMITPHTAFYTTKAVLEMVHQSFDAAVAFAKGEK 324
>CTBP1_MOUSE (O88712) C-terminal-binding protein 1 (EC 1.1.1.-) (CtBP1)| Length = 440 Score = 62.8 bits (151), Expect = 9e-10 Identities = 38/125 (30%), Positives = 63/125 (50%), Gaps = 1/125 (0%) Frame = -1 Query: 664 RXKPFNCNLLYHDRLQINPELEKEIGAKFEEDLDAMLPKCDVVVINTPLTEKTRGMFNKE 485 R K F N+L++D ++ +E+ +G + L +L D V ++ L E + N Sbjct: 192 RAKAFGFNVLFYDPY-LSDGIERALGLQRVSTLQDLLFHSDCVTLHCGLNEHNHHLINDF 250 Query: 484 KIAKMKKGVIIVNNARGAIMDTQAVADACSSGHIAGYGGDVWFPQP-APKDHPWRYMPNH 308 + +M++G +VN ARG ++D +A+A A G I G DV +P + P + PN Sbjct: 251 TVKQMRQGAFLVNTARGGLVDEKALAQALKEGRIRGAALDVHESEPFSFSQGPLKDAPNL 310 Query: 307 AMTPH 293 TPH Sbjct: 311 ICTPH 315
>CTBP1_RAT (Q9Z2F5) C-terminal-binding protein 1 (EC 1.1.1.-) (CtBP1)| (C-terminal-binding protein 3) (CtBP3) (50 kDa BFA-dependent ADP-ribosylation substrate) (BARS-50) Length = 430 Score = 62.8 bits (151), Expect = 9e-10 Identities = 38/125 (30%), Positives = 63/125 (50%), Gaps = 1/125 (0%) Frame = -1 Query: 664 RXKPFNCNLLYHDRLQINPELEKEIGAKFEEDLDAMLPKCDVVVINTPLTEKTRGMFNKE 485 R K F N+L++D ++ +E+ +G + L +L D V ++ L E + N Sbjct: 181 RAKAFGFNVLFYDPY-LSDGIERALGLQRVSTLQDLLFHSDCVTLHCGLNEHNHHLINDF 239 Query: 484 KIAKMKKGVIIVNNARGAIMDTQAVADACSSGHIAGYGGDVWFPQP-APKDHPWRYMPNH 308 + +M++G +VN ARG ++D +A+A A G I G DV +P + P + PN Sbjct: 240 TVKQMRQGAFLVNTARGGLVDEKALAQALKEGRIRGAALDVHESEPFSFSQGPLKDAPNL 299 Query: 307 AMTPH 293 TPH Sbjct: 300 ICTPH 304
>CTBP1_HUMAN (Q13363) C-terminal-binding protein 1 (EC 1.1.1.-) (CtBP1)| Length = 440 Score = 62.4 bits (150), Expect = 1e-09 Identities = 38/125 (30%), Positives = 63/125 (50%), Gaps = 1/125 (0%) Frame = -1 Query: 664 RXKPFNCNLLYHDRLQINPELEKEIGAKFEEDLDAMLPKCDVVVINTPLTEKTRGMFNKE 485 R K F N+L++D ++ +E+ +G + L +L D V ++ L E + N Sbjct: 192 RAKAFGFNVLFYDPY-LSDGVERALGLQRVSTLQDLLFHSDCVTLHCGLNEHNHHLINDF 250 Query: 484 KIAKMKKGVIIVNNARGAIMDTQAVADACSSGHIAGYGGDVWFPQP-APKDHPWRYMPNH 308 + +M++G +VN ARG ++D +A+A A G I G DV +P + P + PN Sbjct: 251 TVKQMRQGAFLVNTARGGLVDEKALAQALKEGRIRGAALDVHESEPFSFSQGPLKDAPNL 310 Query: 307 AMTPH 293 TPH Sbjct: 311 ICTPH 315
>LDHD_LACHE (P30901) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific| D-2-hydroxyacid dehydrogenase) Length = 336 Score = 62.4 bits (150), Expect = 1e-09 Identities = 43/141 (30%), Positives = 67/141 (47%), Gaps = 13/141 (9%) Frame = -1 Query: 652 FNCNLLYHDRLQINPELEKEIGAKFEEDLDAMLPKCDVVVINTPLTEKTRGMFNKEKIAK 473 F ++ +D + NPELEK+ + + LD + + DV+ ++ P M N + IA+ Sbjct: 167 FGAKVIAYDIFK-NPELEKK--GYYVDSLDDLYKQADVISLHVPDVPANVHMINDKSIAE 223 Query: 472 MKKGVIIVNNARGAIMDTQAVADACSSGHIAGYGGDVWFPQPAPKDHPWR---------- 323 MK GV+IVN +RG ++DT AV SG I G+ D + + + W Sbjct: 224 MKDGVVIVNCSRGRLVDTDAVIRGLDSGKIFGFVMDTYEDEVGVFNKDWEGKEFPDKRLA 283 Query: 322 ---YMPNHAMTPHISGTTIDA 269 PN +TPH + T A Sbjct: 284 DLIDRPNVLVTPHTAFYTTHA 304
>LDHD_TREPA (O83080) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific| D-2-hydroxyacid dehydrogenase) Length = 331 Score = 62.0 bits (149), Expect = 2e-09 Identities = 33/81 (40%), Positives = 51/81 (62%), Gaps = 2/81 (2%) Frame = -1 Query: 568 LDAMLPKCDVVVINTPLTEKTRGMFNKEKIAKMKKGVIIVNNARGAIMDTQAVADACSSG 389 +D +L DV+ ++ P T+ + + N + IA+MK GV +VN ARGA++D+QA+ D+ G Sbjct: 192 MDELLSTSDVISLHMPATKDSHHLINAKTIAQMKDGVYLVNTARGAVIDSQALLDSLDKG 251 Query: 388 HIAGYGGDVW-FPQP-APKDH 332 IAG D + F P PKD+ Sbjct: 252 KIAGAALDAYEFEGPYIPKDN 272
>CTBPB_XENLA (Q9W758) C-terminal-binding protein B (TCF-3 corepressor CtBP)| (XCtBP) Length = 437 Score = 61.2 bits (147), Expect = 3e-09 Identities = 37/125 (29%), Positives = 62/125 (49%), Gaps = 1/125 (0%) Frame = -1 Query: 664 RXKPFNCNLLYHDRLQINPELEKEIGAKFEEDLDAMLPKCDVVVINTPLTEKTRGMFNKE 485 R K FN ++++D + +E+ +G + L +L D + ++ L E + N Sbjct: 195 RAKAFNFTVIFYDPY-LADGVERSLGLQRMATLQELLMHSDCITLHCNLNEHNHHLINDF 253 Query: 484 KIAKMKKGVIIVNNARGAIMDTQAVADACSSGHIAGYGGDVWFPQP-APKDHPWRYMPNH 308 I +M++G +VN ARG ++D +A+A A G I G DV +P + P + PN Sbjct: 254 TIKQMRQGCFLVNTARGGLVDEKALAQALKDGRIRGAALDVHESEPFSFSQGPLKDAPNL 313 Query: 307 AMTPH 293 TPH Sbjct: 314 ICTPH 318
>CTBPA_XENLA (Q9YHU0) C-terminal-binding protein A (CtBP)| Length = 440 Score = 61.2 bits (147), Expect = 3e-09 Identities = 38/125 (30%), Positives = 62/125 (49%), Gaps = 1/125 (0%) Frame = -1 Query: 664 RXKPFNCNLLYHDRLQINPELEKEIGAKFEEDLDAMLPKCDVVVINTPLTEKTRGMFNKE 485 R K F N+ ++D ++ +E+ +G + L +L D V ++ L E + N Sbjct: 192 RAKTFGFNVFFYDPY-LSDGIERALGLQRVSTLQDLLFHSDCVTLHCGLNEHNHHLINDF 250 Query: 484 KIAKMKKGVIIVNNARGAIMDTQAVADACSSGHIAGYGGDVWFPQP-APKDHPWRYMPNH 308 I +M++G +VN ARG ++D +A+A A G I G DV +P + P + PN Sbjct: 251 TIKQMRQGAFLVNTARGGLVDEKALAQALKEGRIRGAALDVHESEPFSFTQGPLKDAPNL 310 Query: 307 AMTPH 293 TPH Sbjct: 311 ICTPH 315
>PTXD_PSEST (O69054) Phosphonate dehydrogenase (EC 1.20.1.1) (NAD-dependent| phosphite dehydrogenase) Length = 336 Score = 60.8 bits (146), Expect = 3e-09 Identities = 36/132 (27%), Positives = 62/132 (46%), Gaps = 7/132 (5%) Frame = -1 Query: 664 RXKPFNCNLLYHDRLQINPELEKEIGAKFEEDLDAMLPKCDVVVINTPLTEKTRGMFNKE 485 R + + L YH+ ++ + E+ +G + + + D +++ PL T+ + N E Sbjct: 163 RLQGWGATLQYHEAKALDTQTEQRLGLR-QVACSELFASSDFILLALPLNADTQHLVNAE 221 Query: 484 KIAKMKKGVIIVNNARGAIMDTQAVADACSSGHIAGYGGDV-----WFPQPAPK--DHPW 326 +A ++ G ++VN RG+++D AV A G + GY DV W P+ D Sbjct: 222 LLALVRPGALLVNPCRGSVVDEAAVLAALERGQLGGYAADVFEMEDWARADRPRLIDPAL 281 Query: 325 RYMPNHAMTPHI 290 PN TPHI Sbjct: 282 LAHPNTLFTPHI 293
>CTBP2_MOUSE (P56546) C-terminal-binding protein 2 (CtBP2)| Length = 445 Score = 60.5 bits (145), Expect = 4e-09 Identities = 41/151 (27%), Positives = 70/151 (46%), Gaps = 1/151 (0%) Frame = -1 Query: 664 RXKPFNCNLLYHDRLQINPELEKEIGAKFEEDLDAMLPKCDVVVINTPLTEKTRGMFNKE 485 R K F +++++D + +E+ +G + L +L + D V ++ L E + N Sbjct: 198 RAKAFGFSVIFYDPY-LQDGIERSLGVQRVYTLQDLLYQSDCVSLHCNLNEHNHHLINDF 256 Query: 484 KIAKMKKGVIIVNNARGAIMDTQAVADACSSGHIAGYGGDVWFPQP-APKDHPWRYMPNH 308 I +M++G +VN ARG ++D +A+A A G I G DV +P + P + PN Sbjct: 257 TIKQMRQGAFLVNAARGGLVDEKALAQALKEGRIRGAALDVHESEPFSFAQGPLKDAPNL 316 Query: 307 AMTPHISGTTIDAQLRYAAGVKDMLDRYFKG 215 TPH + + A L + R G Sbjct: 317 ICTPHTAWYSEQASLEMREAAATEIRRAITG 347
>CTBP2_HUMAN (P56545) C-terminal-binding protein 2 (CtBP2)| Length = 445 Score = 60.5 bits (145), Expect = 4e-09 Identities = 41/151 (27%), Positives = 70/151 (46%), Gaps = 1/151 (0%) Frame = -1 Query: 664 RXKPFNCNLLYHDRLQINPELEKEIGAKFEEDLDAMLPKCDVVVINTPLTEKTRGMFNKE 485 R K F +++++D + +E+ +G + L +L + D V ++ L E + N Sbjct: 198 RAKAFGFSVIFYDPY-LQDGIERSLGVQRVYTLQDLLYQSDCVSLHCNLNEHNHHLINDF 256 Query: 484 KIAKMKKGVIIVNNARGAIMDTQAVADACSSGHIAGYGGDVWFPQP-APKDHPWRYMPNH 308 I +M++G +VN ARG ++D +A+A A G I G DV +P + P + PN Sbjct: 257 TIKQMRQGAFLVNAARGGLVDEKALAQALKEGRIRGAALDVHESEPFSFAQGPLKDAPNL 316 Query: 307 AMTPHISGTTIDAQLRYAAGVKDMLDRYFKG 215 TPH + + A L + R G Sbjct: 317 ICTPHTAWYSEQASLEMREAAATEIRRAITG 347
>YCDW_ECOLI (P75913) Putative 2-hydroxyacid dehydrogenase ycdW (EC 1.-.-.-)| Length = 325 Score = 58.5 bits (140), Expect = 2e-08 Identities = 32/103 (31%), Positives = 54/103 (52%) Frame = -1 Query: 574 EDLDAMLPKCDVVVINTPLTEKTRGMFNKEKIAKMKKGVIIVNNARGAIMDTQAVADACS 395 E+L A L +C V++ P T +T G+ N++ + K+ G ++N ARG + + A Sbjct: 195 EELSAFLSQCRVLINLLPNTPETVGIINQQLLEKLPDGAYLLNLARGVHVVEDDLLAALD 254 Query: 394 SGHIAGYGGDVWFPQPAPKDHPWRYMPNHAMTPHISGTTIDAQ 266 SG + G DV+ +P P + P P +TPH++ T A+ Sbjct: 255 SGKVKGAMLDVFNREPLPPESPLWQHPRVTITPHVAAITRPAE 297
>LDHD_LACPL (Q88VJ2) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH)| Length = 332 Score = 57.0 bits (136), Expect = 5e-08 Identities = 32/100 (32%), Positives = 54/100 (54%) Frame = -1 Query: 658 KPFNCNLLYHDRLQINPELEKEIGAKFEEDLDAMLPKCDVVVINTPLTEKTRGMFNKEKI 479 K F ++ +D + N ELEKE + + LD + + DV+ ++ P + M N + Sbjct: 165 KGFGAKVIGYDVYR-NAELEKE--GMYVDTLDELYAQADVITLHVPALKDNYHMLNADAF 221 Query: 478 AKMKKGVIIVNNARGAIMDTQAVADACSSGHIAGYGGDVW 359 +KMK G I+N ARG ++D++ + A SG +AG D + Sbjct: 222 SKMKDGAYILNFARGTLIDSEDLIKALDSGKVAGAALDTY 261
>LDHD_STRP1 (Q99ZM2) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific| D-2-hydroxyacid dehydrogenase) Length = 330 Score = 57.0 bits (136), Expect = 5e-08 Identities = 42/143 (29%), Positives = 73/143 (51%), Gaps = 13/143 (9%) Frame = -1 Query: 658 KPFNCNLLYHDRLQINPELEKEIGAKFEEDLDAMLPKCDVVVINTPLTEKTRGMFNKEKI 479 K F C ++ +D Q + K + ++E ++ + D+V ++ P T + +FN + Sbjct: 165 KGFGCKVVGYDIYQ--SDAAKAV-LDYKESVEEAIKDADLVSLHMPPTAENTHLFNSDLF 221 Query: 478 AKMKKGVIIVNNARGAIMDTQAVADACSSGHIAGYGGDVW-FPQP-APK--------DHP 329 KKG I++N ARGA+++TQ + DA +G ++G G D + F P PK D Sbjct: 222 KSFKKGAILMNMARGAVIETQDLLDALDAGLLSGAGIDTYEFEGPYIPKNFEGQEITDSL 281 Query: 328 WRYMPNH---AMTPHISGTTIDA 269 ++ + NH TPH + T +A Sbjct: 282 FKALINHPKVIYTPHAAYYTDEA 304
>LDHD_PEDAC (Q59642) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific| D-2-hydroxyacid dehydrogenase) Length = 331 Score = 56.6 bits (135), Expect = 6e-08 Identities = 30/100 (30%), Positives = 55/100 (55%) Frame = -1 Query: 658 KPFNCNLLYHDRLQINPELEKEIGAKFEEDLDAMLPKCDVVVINTPLTEKTRGMFNKEKI 479 KPF ++ +D + NP LEKE + + L+ + + +V+ ++ P + M +++ Sbjct: 164 KPFGAKVIAYDVFR-NPALEKE--GMYVDTLEELYQQANVITLHVPALKDNYHMLDEKAF 220 Query: 478 AKMKKGVIIVNNARGAIMDTQAVADACSSGHIAGYGGDVW 359 +M+ G I+N ARG ++DT A+ A SG +AG D + Sbjct: 221 GQMQDGTFILNFARGTLVDTPALLKALDSGKVAGAALDTY 260
>LDHD_ECOLI (P52643) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH)| (Fermentative lactate dehydrogenase) Length = 329 Score = 56.6 bits (135), Expect = 6e-08 Identities = 28/79 (35%), Positives = 48/79 (60%) Frame = -1 Query: 595 EIGAKFEEDLDAMLPKCDVVVINTPLTEKTRGMFNKEKIAKMKKGVIIVNNARGAIMDTQ 416 E+G ++ DL + + DV+ ++ PLT + + N+ +MK GV+IVN +RGA++D+Q Sbjct: 183 ELGVEYV-DLPTLFSESDVISLHCPLTPENYHLLNEAAFEQMKNGVMIVNTSRGALIDSQ 241 Query: 415 AVADACSSGHIAGYGGDVW 359 A +A + I G DV+ Sbjct: 242 AAIEALKNQKIGSLGMDVY 260
>LDHD_LACPE (P26298) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific| D-2-hydroxyacid dehydrogenase) Length = 332 Score = 56.2 bits (134), Expect = 8e-08 Identities = 31/94 (32%), Positives = 52/94 (55%) Frame = -1 Query: 658 KPFNCNLLYHDRLQINPELEKEIGAKFEEDLDAMLPKCDVVVINTPLTEKTRGMFNKEKI 479 K F ++ +D + N ELEKE + + LD + + DV+ ++ P + M N + Sbjct: 165 KGFGAKVIGYDVYR-NAELEKE--GMYVDTLDELYAQADVITLHVPALKDNYHMLNADAF 221 Query: 478 AKMKKGVIIVNNARGAIMDTQAVADACSSGHIAG 377 +KMK G I+N ARG ++D++ + A SG +AG Sbjct: 222 SKMKDGAYILNFARGTLIDSEDLIKALDSGKVAG 255
>PDXB_PSEAE (Q9I3W9) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| Length = 380 Score = 54.7 bits (130), Expect = 2e-07 Identities = 33/112 (29%), Positives = 59/112 (52%), Gaps = 4/112 (3%) Frame = -1 Query: 568 LDAMLPKCDVVVINTPLTEK----TRGMFNKEKIAKMKKGVIIVNNARGAIMDTQAVADA 401 L+ +L + DV+ ++TPL TR + ++ ++A ++ G +VN +RGA++D QA+ Sbjct: 161 LERLLAEADVISLHTPLNRDGEHPTRHLLDEPRLAALRPGTWLVNASRGAVVDNQALRRL 220 Query: 400 CSSGHIAGYGGDVWFPQPAPKDHPWRYMPNHAMTPHISGTTIDAQLRYAAGV 245 G DVW + P+ P TPHI+G +++ +LR A + Sbjct: 221 LEGGADLEVALDVW--EGEPQADPELAARCLIATPHIAGYSLEGKLRGTAQI 270
>VANH_ENTFC (Q05709) D-specific alpha-keto acid dehydrogenase (EC 1.1.1.-)| (Vancomycin resistance protein vanH) Length = 322 Score = 53.1 bits (126), Expect = 7e-07 Identities = 38/145 (26%), Positives = 65/145 (44%), Gaps = 13/145 (8%) Frame = -1 Query: 664 RXKPFNCNLLYHDRLQINPELEKEIGAKFEEDLDAMLPKCDVVVINTPLTEKTRGMFNKE 485 R + F C +L + R + I + D +L D+V ++ PL T + + E Sbjct: 164 RLRGFGCKVLAYSR-------SRSIEVNYVP-FDELLQNSDIVTLHVPLNTDTHYIISHE 215 Query: 484 KIAKMKKGVIIVNNARGAIMDTQAVADACSSGHIAGYGGDVWFPQ---------PAPKDH 332 +I +MK+G ++N RG ++DT + A +G + G DV + P D+ Sbjct: 216 QIQRMKQGAFLINTGRGPLVDTYELVKALENGKLGGAALDVLEGEEEFFYSDCTQKPIDN 275 Query: 331 PW----RYMPNHAMTPHISGTTIDA 269 + + MPN +TPH + T A Sbjct: 276 QFLLKLQRMPNVIITPHTAYYTEQA 300
>LDHD_STRA3 (Q8E6A9) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific| D-2-hydroxyacid dehydrogenase) Length = 330 Score = 52.4 bits (124), Expect = 1e-06 Identities = 28/100 (28%), Positives = 56/100 (56%) Frame = -1 Query: 658 KPFNCNLLYHDRLQINPELEKEIGAKFEEDLDAMLPKCDVVVINTPLTEKTRGMFNKEKI 479 K F C ++ +D + NP + + ++ ++ + K D+V ++ P T + +FN + Sbjct: 165 KGFGCRVIGYD-IYHNPMADGIL--EYVNSVEEAVEKADLVSLHMPPTAENTHLFNLDMF 221 Query: 478 AKMKKGVIIVNNARGAIMDTQAVADACSSGHIAGYGGDVW 359 + KKG I++N ARGA+++T+ + +A G + G G D + Sbjct: 222 KQFKKGAILMNMARGALVETKDLLEALDQGLLEGAGIDTY 261
>DHGY_CUCSA (P13443) Glycerate dehydrogenase (EC 1.1.1.29) (NADH-dependent| hydroxypyruvate reductase) (HPR) (GDH) Length = 382 Score = 52.4 bits (124), Expect = 1e-06 Identities = 40/140 (28%), Positives = 64/140 (45%), Gaps = 15/140 (10%) Frame = -1 Query: 652 FNCNLLYHDRLQINPELEKEIGAKFE---------------EDLDAMLPKCDVVVINTPL 518 F NL+Y D Q + LEK + A E +D +L + DV+ ++ L Sbjct: 188 FKMNLIYFDLYQ-STRLEKFVTAYGEFLKANGEAPVTWRRASSMDEVLREADVISLHPVL 246 Query: 517 TEKTRGMFNKEKIAKMKKGVIIVNNARGAIMDTQAVADACSSGHIAGYGGDVWFPQPAPK 338 + T + NKE + MKK I++N +RG ++D A+ D + G DV+ +P K Sbjct: 247 DKTTFHLVNKESLKAMKKDAILINCSRGPVIDEAALVDHLRDNPMFRVGLDVFEDEPYMK 306 Query: 337 DHPWRYMPNHAMTPHISGTT 278 M N + PHI+ + Sbjct: 307 P-GLADMKNAIIVPHIASAS 325
>YGT5_YEAST (P53100) Putative 2-hydroxyacid dehydrogenase YGL185C (EC 1.-.-.-)| Length = 379 Score = 52.4 bits (124), Expect = 1e-06 Identities = 31/102 (30%), Positives = 53/102 (51%) Frame = -1 Query: 577 EEDLDAMLPKCDVVVINTPLTEKTRGMFNKEKIAKMKKGVIIVNNARGAIMDTQAVADAC 398 +E + A L + +V+ P T +T + N++ + G+I+VN RG I+D +AV+DA Sbjct: 247 DETIYAKLYQFHAIVVTLPGTPQTEHLINRKFLEHCNPGLILVNLGRGKILDLRAVSDAL 306 Query: 397 SSGHIAGYGGDVWFPQPAPKDHPWRYMPNHAMTPHISGTTID 272 +G I G DV+ +P + ++TPH+ T D Sbjct: 307 VTGRINHLGLDVFNKEPEIDEKIRSSDRLTSITPHLGSATKD 348
>CTBP_DROME (O46036) C-terminal-binding protein (CtBP protein) (dCtBP)| Length = 476 Score = 52.0 bits (123), Expect = 2e-06 Identities = 38/130 (29%), Positives = 60/130 (46%), Gaps = 6/130 (4%) Frame = -1 Query: 664 RXKPFNCNLLYHDRLQINPELEKEIGAKFEEDLDAMLPKCDVVVINTPLTEKTRGMFNKE 485 R K F N++++D + ++K +G L +L + D V ++ L E + N+ Sbjct: 192 RAKAFGFNVIFYDPY-LPDGIDKSLGLTRVYTLQDLLFQSDCVSLHCTLNEHNHHLINEF 250 Query: 484 KIAKMKKGVIIVNNARGAIMDTQAVADACSSGHIAGYGGDVWFPQP------APKDHPWR 323 I +M+ G +VN ARG ++D + +A A G I DV +P A KD Sbjct: 251 TIKQMRPGAFLVNTARGGLVDDETLALALKQGRIRAAALDVHENEPYNVFQGALKD---- 306 Query: 322 YMPNHAMTPH 293 PN TPH Sbjct: 307 -APNLICTPH 315
>YMP5_STRCO (P43169) Hypothetical protein in mprR 3'region (EC 1.-.-.-) (ORF5)| (Fragment) Length = 278 Score = 51.2 bits (121), Expect = 3e-06 Identities = 33/109 (30%), Positives = 52/109 (47%), Gaps = 5/109 (4%) Frame = -1 Query: 589 GAKFEEDLDA-----MLPKCDVVVINTPLTEKTRGMFNKEKIAKMKKGVIIVNNARGAIM 425 G F+E + A L + VV PLT+ TR F +++ ++ G +N RGA + Sbjct: 139 GGPFDERITAGEDGPWLGRARFVVDALPLTDATRDFFADARLSALR-GATFLNVGRGATV 197 Query: 424 DTQAVADACSSGHIAGYGGDVWFPQPAPKDHPWRYMPNHAMTPHISGTT 278 A+ A ++GH+ G DV +P HP +P +T H +G T Sbjct: 198 SLPALGRALAAGHVRGAVLDVLTDEPPAPGHPVWELPRTTLTSHSAGIT 246
>PDXB_SHIFL (Q83QR1) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| Length = 378 Score = 51.2 bits (121), Expect = 3e-06 Identities = 32/124 (25%), Positives = 61/124 (49%), Gaps = 4/124 (3%) Frame = -1 Query: 568 LDAMLPKCDVVVINTPLTE----KTRGMFNKEKIAKMKKGVIIVNNARGAIMDTQAVADA 401 LD ++ + D++ +TPL + KT + +++ I +K G I++N RGA++D A+ Sbjct: 161 LDELVQRADILTFHTPLFKDGPYKTLHLADEKLIRSLKPGAILINACRGAVVDNTALLTC 220 Query: 400 CSSGHIAGYGGDVWFPQPAPKDHPWRYMPNHAMTPHISGTTIDAQLRYAAGVKDMLDRYF 221 + G DVW + P+ + TPHI+G T++ + R V + ++ Sbjct: 221 LNEGQKLSVVLDVW--EGEPELNVELLTKVDIGTPHIAGYTLEGKARGTTQVFEAYSKFI 278 Query: 220 KGEE 209 E+ Sbjct: 279 GHEQ 282
>PDXB_ECO57 (Q8XCR0) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| Length = 378 Score = 51.2 bits (121), Expect = 3e-06 Identities = 32/124 (25%), Positives = 61/124 (49%), Gaps = 4/124 (3%) Frame = -1 Query: 568 LDAMLPKCDVVVINTPLTE----KTRGMFNKEKIAKMKKGVIIVNNARGAIMDTQAVADA 401 LD ++ + D++ +TPL + KT + +++ I +K G I++N RGA++D A+ Sbjct: 161 LDELVQRADILTFHTPLFKDGPYKTLHLADEKLIRSLKPGAILINACRGAVVDNTALLTC 220 Query: 400 CSSGHIAGYGGDVWFPQPAPKDHPWRYMPNHAMTPHISGTTIDAQLRYAAGVKDMLDRYF 221 + G DVW + P+ + TPHI+G T++ + R V + ++ Sbjct: 221 LNEGQKLSVVLDVW--EGEPELNVELLTKVDIGTPHIAGYTLEGKARGTTQVFEAYSKFI 278 Query: 220 KGEE 209 E+ Sbjct: 279 GHEQ 282
>LDHD_STRA5 (Q8E0N5) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific| D-2-hydroxyacid dehydrogenase) Length = 330 Score = 50.8 bits (120), Expect = 4e-06 Identities = 27/100 (27%), Positives = 56/100 (56%) Frame = -1 Query: 658 KPFNCNLLYHDRLQINPELEKEIGAKFEEDLDAMLPKCDVVVINTPLTEKTRGMFNKEKI 479 K F C ++ +D + NP + + ++ ++ + + D+V ++ P T + +FN + Sbjct: 165 KGFGCRVIGYD-IYHNPMADGIL--EYVNSVEEAVEEADLVSLHMPPTAENTHLFNLDMF 221 Query: 478 AKMKKGVIIVNNARGAIMDTQAVADACSSGHIAGYGGDVW 359 + KKG I++N ARGA+++T+ + +A G + G G D + Sbjct: 222 KQFKKGAILMNMARGALVETKDLLEALDQGLLEGAGIDTY 261
>DHD2_LACPA (P17584) D-2-hydroxyisocaproate dehydrogenase (EC 1.1.1.-)| (D-HICDH) Length = 333 Score = 50.8 bits (120), Expect = 4e-06 Identities = 32/107 (29%), Positives = 52/107 (48%), Gaps = 13/107 (12%) Frame = -1 Query: 568 LDAMLPKCDVVVINTPLTEKTRGMFNKEKIAKMKKGVIIVNNARGAIMDTQAVADACSSG 389 L+ + + DV+ ++ P E+ + N+ MK G I++N AR ++DTQA+ SG Sbjct: 191 LEDLFKQSDVIDLHVPGIEQNTHIINEAAFNLMKPGAIVINTARPNLIDTQAMLSNLKSG 250 Query: 388 HIAGYGGDVWFPQPAP----------KDHPWRY---MPNHAMTPHIS 287 +AG G D + + KD W MPN ++PHI+ Sbjct: 251 KLAGVGIDTYEYETEDLLNLAKHGSFKDPLWDELLGMPNVVLSPHIA 297
>PDXB_ECOL6 (Q8FFH2) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| Length = 378 Score = 50.8 bits (120), Expect = 4e-06 Identities = 32/124 (25%), Positives = 60/124 (48%), Gaps = 4/124 (3%) Frame = -1 Query: 568 LDAMLPKCDVVVINTPLTE----KTRGMFNKEKIAKMKKGVIIVNNARGAIMDTQAVADA 401 LD ++ D++ +TPL + KT + +++ I +K G I++N RGA++D A+ Sbjct: 161 LDELVQHADILTFHTPLFKDGPYKTLHLADEKLIRSLKPGAILINACRGAVVDNTALLTC 220 Query: 400 CSSGHIAGYGGDVWFPQPAPKDHPWRYMPNHAMTPHISGTTIDAQLRYAAGVKDMLDRYF 221 + G DVW +P + + TPHI+G T++ + R V + ++ Sbjct: 221 LNEGQKLSVVLDVWEGEPELNVELLKKV--DIGTPHIAGYTLEGKARGTTQVFEAYSKFI 278 Query: 220 KGEE 209 E+ Sbjct: 279 GHEQ 282
>PDXB_PSESM (Q884R9) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| Length = 380 Score = 50.4 bits (119), Expect = 5e-06 Identities = 37/141 (26%), Positives = 68/141 (48%), Gaps = 11/141 (7%) Frame = -1 Query: 622 LQINPELEKEIGAKFEEDLDAMLPKCDVVVINTPLTEK----TRGMFNKEKIAKMKKGVI 455 L +P + G F LD +L +CDV+ ++TPL + T + ++ ++ ++++G Sbjct: 143 LVCDPPRQSAEGGDFVS-LDEILQRCDVISLHTPLDKSGQSPTWHLLDEARLRQLRQGAW 201 Query: 454 IVNNARGAIMDTQAVADACSSGHIAGYGGDVWFPQPAPKDHPWRYMPNHAM-------TP 296 ++N +RGA++D +A+ D DVW +P N A+ TP Sbjct: 202 LINASRGAVVDNRALHDVMLEREDLQAVLDVWEGEP---------QVNVALADLCVIGTP 252 Query: 295 HISGTTIDAQLRYAAGVKDML 233 HI+G ++D + R A + L Sbjct: 253 HIAGYSLDGRQRGTAQIYQAL 273
>PDXB_BACTN (Q8A2E4) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| Length = 348 Score = 48.9 bits (115), Expect = 1e-05 Identities = 34/136 (25%), Positives = 66/136 (48%), Gaps = 6/136 (4%) Frame = -1 Query: 610 PELEKEIGAKFEEDLDAMLPKCDVVVINTPLTE----KTRGMFNKEKIAKMKKGVIIVNN 443 P EKE F L+ + +CD++ + PL + KT + + +++ +++N Sbjct: 149 PREEKEGNITFTS-LEKIAEECDIITFHVPLYKEGKYKTYHLADGNFFRSLQRKPVVINT 207 Query: 442 ARGAIMDTQAVADACSSGHIAGYGGDVWFPQPAPKDHPWRYMPNHAM--TPHISGTTIDA 269 +RG +++T A+ +A ++G I+ DVW +P R + + TPHI+G + D Sbjct: 208 SRGEVIETNALLEAINNGIISDAVIDVWEHEPEIN----RELLEKVLIGTPHIAGYSADG 263 Query: 268 QLRYAAGVKDMLDRYF 221 + D + R+F Sbjct: 264 KANATRMSLDSICRFF 279
>LDHD_STAAR (Q6GDS2) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific| D-2-hydroxyacid dehydrogenase) Length = 330 Score = 48.9 bits (115), Expect = 1e-05 Identities = 22/85 (25%), Positives = 47/85 (55%) Frame = -1 Query: 580 FEEDLDAMLPKCDVVVINTPLTEKTRGMFNKEKIAKMKKGVIIVNNARGAIMDTQAVADA 401 +++ + + D++ ++ P +++ +F+K +KKG I+VN ARGA+++T + DA Sbjct: 188 YKDSVKEAIKDADIISLHVPANKESYHLFDKTMFDHVKKGAILVNAARGAVINTPDLIDA 247 Query: 400 CSSGHIAGYGGDVWFPQPAPKDHPW 326 + G + G D + + A + W Sbjct: 248 VNDGTLLGAAIDTYENEAAYFTNDW 272
>PDXB_ECOLI (P05459) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| Length = 378 Score = 48.9 bits (115), Expect = 1e-05 Identities = 31/124 (25%), Positives = 60/124 (48%), Gaps = 4/124 (3%) Frame = -1 Query: 568 LDAMLPKCDVVVINTPLTE----KTRGMFNKEKIAKMKKGVIIVNNARGAIMDTQAVADA 401 LD ++ + D++ +TPL + KT + +++ I +K G I++N RGA++D A+ Sbjct: 161 LDELVQRADILTFHTPLFKDGPYKTLHLADEKLIRSLKPGAILINACRGAVVDNTALLTC 220 Query: 400 CSSGHIAGYGGDVWFPQPAPKDHPWRYMPNHAMTPHISGTTIDAQLRYAAGVKDMLDRYF 221 + G DVW +P + + T HI+G T++ + R V + ++ Sbjct: 221 LNEGQKLSVVLDVWEGEPELNVELLKKV--DIGTSHIAGYTLEGKARGTTQVFEAYSKFI 278 Query: 220 KGEE 209 E+ Sbjct: 279 GHEQ 282
>PDXB_YERPS (Q668W7) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| Length = 375 Score = 48.5 bits (114), Expect = 2e-05 Identities = 33/111 (29%), Positives = 56/111 (50%), Gaps = 8/111 (7%) Frame = -1 Query: 568 LDAMLPKCDVVVINTPLTE----KTRGMFNKEKIAKMKKGVIIVNNARGAIMDTQAVADA 401 L+ ++ + DV+ +TPL + ++ M + E +A + G I++N RGA++D A+ A Sbjct: 161 LEKLVREADVLTFHTPLNKTGAYQSLHMADDELLAALPDGRILINACRGAVVDNAALLRA 220 Query: 400 CSSGHIAGYGGDVWFPQPAPKDHPWRYMPNHAM----TPHISGTTIDAQLR 260 G DVW P+P +P A TPHI+G T++ + R Sbjct: 221 LEKGKKLSVVLDVWEPEPDLS------LPLLARVDIGTPHIAGYTLEGKAR 265
>PDXB_YERPE (Q8D0U3) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| Length = 375 Score = 48.5 bits (114), Expect = 2e-05 Identities = 33/111 (29%), Positives = 56/111 (50%), Gaps = 8/111 (7%) Frame = -1 Query: 568 LDAMLPKCDVVVINTPLTE----KTRGMFNKEKIAKMKKGVIIVNNARGAIMDTQAVADA 401 L+ ++ + DV+ +TPL + ++ M + E +A + G I++N RGA++D A+ A Sbjct: 161 LEKLVREADVLTFHTPLNKTGAYQSLHMADDELLAALPDGRILINACRGAVVDNAALLRA 220 Query: 400 CSSGHIAGYGGDVWFPQPAPKDHPWRYMPNHAM----TPHISGTTIDAQLR 260 G DVW P+P +P A TPHI+G T++ + R Sbjct: 221 LEKGKKLSVVLDVWEPEPDLS------LPLLARVDIGTPHIAGYTLEGKAR 265
>PDXB_SHESP (Q56731) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| (Fragment) Length = 274 Score = 48.1 bits (113), Expect = 2e-05 Identities = 29/107 (27%), Positives = 55/107 (51%), Gaps = 4/107 (3%) Frame = -1 Query: 568 LDAMLPKCDVVVINTPLTE----KTRGMFNKEKIAKMKKGVIIVNNARGAIMDTQAVADA 401 LD ++ CDV+ ++ P+T+ KT +F++ ++ +K+G ++N RG ++D QA+ Sbjct: 48 LDELIACCDVISLHVPITKTGEHKTWYLFDEARLNSLKQGTWLLNCCRGEVIDNQALIKV 107 Query: 400 CSSGHIAGYGGDVWFPQPAPKDHPWRYMPNHAMTPHISGTTIDAQLR 260 DVW +P P + TPHI+G +++ + R Sbjct: 108 KLERPDIKLVLDVWEGEPNPMHELIPLV--ELATPHIAGYSLEGKAR 152
>PDXB_VIBVY (Q7MIT6) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| Length = 377 Score = 47.8 bits (112), Expect = 3e-05 Identities = 35/128 (27%), Positives = 64/128 (50%), Gaps = 6/128 (4%) Frame = -1 Query: 625 RLQINPELEKEIGAKFE-EDLDAMLPKCDVVVINTPLTEK----TRGMFNKEKIAKMKKG 461 ++ IN ++E G + E LD +L + DV+ ++TP+T T + NKE + ++ Sbjct: 142 KVLINDPFKQEEGDEREFTSLDRLLQEADVITLHTPITRDGKYPTHHLINKEILNSLRAD 201 Query: 460 VIIVNNARGAIMDTQAVADACSSGHIAGYGGDVWFPQPAPKDHPWRYMPNHAM-TPHISG 284 I++N ARG ++D QA+ DV+ +P + +P A TPH++G Sbjct: 202 QILINAARGPVVDNQALKHRLQQADGFTAALDVFEFEP---EVDMELLPLLAFATPHVAG 258 Query: 283 TTIDAQLR 260 ++ + R Sbjct: 259 YGLEGKAR 266
>PDXB_PHOLL (Q7N2B2) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| Length = 375 Score = 47.4 bits (111), Expect = 4e-05 Identities = 30/107 (28%), Positives = 56/107 (52%), Gaps = 4/107 (3%) Frame = -1 Query: 568 LDAMLPKCDVVVINTPLTE----KTRGMFNKEKIAKMKKGVIIVNNARGAIMDTQAVADA 401 L+ ++ + D++ +TPL + KT + + E ++ + I++N +RG ++D QA+ A Sbjct: 161 LEKLVKEADILTFHTPLNKSGPYKTHHLVDVELLSVLPDNRILINASRGEVIDNQALLTA 220 Query: 400 CSSGHIAGYGGDVWFPQPAPKDHPWRYMPNHAMTPHISGTTIDAQLR 260 G DVW P+P P + + TPHI+G T++ + R Sbjct: 221 LKCGKKLRVVLDVWEPEP-DLSLPLLELVDIG-TPHIAGYTLEGKAR 265
>LDHD_STAES (Q8CN22) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific| D-2-hydroxyacid dehydrogenase) Length = 330 Score = 46.6 bits (109), Expect = 7e-05 Identities = 18/75 (24%), Positives = 45/75 (60%) Frame = -1 Query: 583 KFEEDLDAMLPKCDVVVINTPLTEKTRGMFNKEKIAKMKKGVIIVNNARGAIMDTQAVAD 404 +++E ++ + D++ ++ P + + +F+ +KKG ++VN ARGA+++T + + Sbjct: 187 EYKETVEDAIKDADIISLHVPANKDSFHLFDNNMFKNVKKGAVLVNAARGAVINTPDLIE 246 Query: 403 ACSSGHIAGYGGDVW 359 A ++G ++G D + Sbjct: 247 AVNNGTLSGAAIDTY 261
>LDHD_STAEQ (Q5HLA0) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific| D-2-hydroxyacid dehydrogenase) Length = 330 Score = 46.6 bits (109), Expect = 7e-05 Identities = 18/75 (24%), Positives = 45/75 (60%) Frame = -1 Query: 583 KFEEDLDAMLPKCDVVVINTPLTEKTRGMFNKEKIAKMKKGVIIVNNARGAIMDTQAVAD 404 +++E ++ + D++ ++ P + + +F+ +KKG ++VN ARGA+++T + + Sbjct: 187 EYKETVEDAIKDADIISLHVPANKDSFHLFDNNMFKNVKKGAVLVNAARGAVINTPDLIE 246 Query: 403 ACSSGHIAGYGGDVW 359 A ++G ++G D + Sbjct: 247 AVNNGTLSGAAIDTY 261
>PDXB_PSEPK (Q88L20) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| Length = 380 Score = 46.2 bits (108), Expect = 9e-05 Identities = 33/119 (27%), Positives = 60/119 (50%), Gaps = 4/119 (3%) Frame = -1 Query: 568 LDAMLPKCDVVVINTPLTE----KTRGMFNKEKIAKMKKGVIIVNNARGAIMDTQAVADA 401 L+ +L +CDV+ ++TPL T + + ++A+++ G +VN +RG ++D A+ + Sbjct: 160 LETILQQCDVISLHTPLQRGGQHPTWHLLGQAQLAQLRPGAWLVNASRGPVVDNVALREL 219 Query: 400 CSSGHIAGYGGDVWFPQPAPKDHPWRYMPNHAMTPHISGTTIDAQLRYAAGVKDMLDRY 224 DVW +P D + A TPHI+G ++D + R A + L R+ Sbjct: 220 LLDREDVHAVLDVWEGEP-QVDLQLADLCTLA-TPHIAGYSLDGRQRGTARIYQALCRF 276
>LDHD_STAAW (Q8NUT2) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific| D-2-hydroxyacid dehydrogenase) Length = 330 Score = 45.8 bits (107), Expect = 1e-04 Identities = 21/85 (24%), Positives = 46/85 (54%) Frame = -1 Query: 580 FEEDLDAMLPKCDVVVINTPLTEKTRGMFNKEKIAKMKKGVIIVNNARGAIMDTQAVADA 401 +++ + + D++ ++ P +++ +F+K +KKG I+VN ARGA+++T + A Sbjct: 188 YKDSVKEAIKDADIISLHVPANKESYHLFDKAMFDHVKKGAILVNAARGAVINTPDLIAA 247 Query: 400 CSSGHIAGYGGDVWFPQPAPKDHPW 326 + G + G D + + A + W Sbjct: 248 VNDGTLLGAAIDTYENEAAYFTNDW 272
>LDHD_STAAU (P72357) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific| D-2-hydroxyacid dehydrogenase) Length = 330 Score = 45.8 bits (107), Expect = 1e-04 Identities = 21/85 (24%), Positives = 46/85 (54%) Frame = -1 Query: 580 FEEDLDAMLPKCDVVVINTPLTEKTRGMFNKEKIAKMKKGVIIVNNARGAIMDTQAVADA 401 +++ + + D++ ++ P +++ +F+K +KKG I+VN ARGA+++T + A Sbjct: 188 YKDSVKEAIKDADIISLHVPANKESYHLFDKAMFDHVKKGAILVNAARGAVINTPDLIAA 247 Query: 400 CSSGHIAGYGGDVWFPQPAPKDHPW 326 + G + G D + + A + W Sbjct: 248 VNDGTLLGAAIDTYENEAAYFTNDW 272
>LDHD_STAAS (Q6G6F1) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific| D-2-hydroxyacid dehydrogenase) Length = 330 Score = 45.8 bits (107), Expect = 1e-04 Identities = 21/85 (24%), Positives = 46/85 (54%) Frame = -1 Query: 580 FEEDLDAMLPKCDVVVINTPLTEKTRGMFNKEKIAKMKKGVIIVNNARGAIMDTQAVADA 401 +++ + + D++ ++ P +++ +F+K +KKG I+VN ARGA+++T + A Sbjct: 188 YKDSVKEAIKDADIISLHVPANKESYHLFDKAMFDHVKKGAILVNAARGAVINTPDLIAA 247 Query: 400 CSSGHIAGYGGDVWFPQPAPKDHPW 326 + G + G D + + A + W Sbjct: 248 VNDGTLLGAAIDTYENEAAYFTNDW 272
>LDHD_STAAN (P99116) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific| D-2-hydroxyacid dehydrogenase) Length = 330 Score = 45.8 bits (107), Expect = 1e-04 Identities = 21/85 (24%), Positives = 46/85 (54%) Frame = -1 Query: 580 FEEDLDAMLPKCDVVVINTPLTEKTRGMFNKEKIAKMKKGVIIVNNARGAIMDTQAVADA 401 +++ + + D++ ++ P +++ +F+K +KKG I+VN ARGA+++T + A Sbjct: 188 YKDSVKEAIKDADIISLHVPANKESYHLFDKAMFDHVKKGAILVNAARGAVINTPDLIAA 247 Query: 400 CSSGHIAGYGGDVWFPQPAPKDHPW 326 + G + G D + + A + W Sbjct: 248 VNDGTLLGAAIDTYENEAAYFTNDW 272
>LDHD_STAAM (P63940) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific| D-2-hydroxyacid dehydrogenase) Length = 330 Score = 45.8 bits (107), Expect = 1e-04 Identities = 21/85 (24%), Positives = 46/85 (54%) Frame = -1 Query: 580 FEEDLDAMLPKCDVVVINTPLTEKTRGMFNKEKIAKMKKGVIIVNNARGAIMDTQAVADA 401 +++ + + D++ ++ P +++ +F+K +KKG I+VN ARGA+++T + A Sbjct: 188 YKDSVKEAIKDADIISLHVPANKESYHLFDKAMFDHVKKGAILVNAARGAVINTPDLIAA 247 Query: 400 CSSGHIAGYGGDVWFPQPAPKDHPW 326 + G + G D + + A + W Sbjct: 248 VNDGTLLGAAIDTYENEAAYFTNDW 272
>LDHD_STAAC (Q5HD29) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific| D-2-hydroxyacid dehydrogenase) Length = 330 Score = 45.8 bits (107), Expect = 1e-04 Identities = 21/85 (24%), Positives = 46/85 (54%) Frame = -1 Query: 580 FEEDLDAMLPKCDVVVINTPLTEKTRGMFNKEKIAKMKKGVIIVNNARGAIMDTQAVADA 401 +++ + + D++ ++ P +++ +F+K +KKG I+VN ARGA+++T + A Sbjct: 188 YKDSVKEAIKDADIISLHVPANKESYHLFDKAMFDHVKKGAILVNAARGAVINTPDLIAA 247 Query: 400 CSSGHIAGYGGDVWFPQPAPKDHPW 326 + G + G D + + A + W Sbjct: 248 VNDGTLLGAAIDTYENEAAYFTNDW 272
>PDXB_VIBVU (Q8DB36) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| Length = 377 Score = 45.4 bits (106), Expect = 1e-04 Identities = 34/128 (26%), Positives = 64/128 (50%), Gaps = 6/128 (4%) Frame = -1 Query: 625 RLQINPELEKEIGAKFE-EDLDAMLPKCDVVVINTPLTEK----TRGMFNKEKIAKMKKG 461 ++ IN ++E G + E LD +L + DV+ ++TP+T T + N+E + ++ Sbjct: 142 KVLINDPFKQEEGDEREFTSLDRLLQEADVITLHTPITRDGKYPTHHLINEEILNSLRAD 201 Query: 460 VIIVNNARGAIMDTQAVADACSSGHIAGYGGDVWFPQPAPKDHPWRYMPNHAM-TPHISG 284 I++N ARG ++D QA+ DV+ +P + +P A TPH++G Sbjct: 202 QILINAARGPVVDNQALKRRLQQADGFMAALDVFEFEP---EVDMELLPLLAFATPHVAG 258 Query: 283 TTIDAQLR 260 ++ + R Sbjct: 259 YGLEGKAR 266
>PDXB_PORGI (Q7MV70) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| Length = 377 Score = 45.1 bits (105), Expect = 2e-04 Identities = 38/128 (29%), Positives = 62/128 (48%), Gaps = 5/128 (3%) Frame = -1 Query: 568 LDAMLPKCDVVVINTPLT-EKTRGMFNKEKIAKMK----KGVIIVNNARGAIMDTQAVAD 404 L ++ +CD++ + PLT E ++ A ++ K I++N RGA+ DTQA+ Sbjct: 169 LSRLVEQCDIISFHVPLTHEDPHATYHLIGEAFLRSCADKRPILINACRGAVADTQALIR 228 Query: 403 ACSSGHIAGYGGDVWFPQPAPKDHPWRYMPNHAMTPHISGTTIDAQLRYAAGVKDMLDRY 224 A SG + D W +P D + + A TPHI+G + D + A + + Sbjct: 229 AVKSGWLQALVIDCWEGEP-DIDLSLLDLADIA-TPHIAGFSADGKANGARMCLEAITEV 286 Query: 223 FKGEEFPV 200 F G EFP+ Sbjct: 287 F-GLEFPL 293
>PDXB_WIGBR (Q8D2P6) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| Length = 378 Score = 44.7 bits (104), Expect = 3e-04 Identities = 31/148 (20%), Positives = 73/148 (49%), Gaps = 6/148 (4%) Frame = -1 Query: 613 NPELEKEIGAKFEEDLDAMLPKCDVVVINTPLTEK----TRGMFNKEKIAKMKKGVIIVN 446 +P LE++ K + L+ ++ D++ ++ PLT T + NK+ + +K I++N Sbjct: 146 DPILEEKNNIKLKS-LNEIVQNSDIITLHVPLTYSGKYPTWHLINKKILLDLKDNCILIN 204 Query: 445 NARGAIMDTQAVADACSSGHIAGYGGDVWFPQPAPKDHPWRYMPNHAMTPHISGTTIDAQ 266 +RG+++D ++ + G DVW +P + TPHI+G +++ + Sbjct: 205 TSRGSVIDNNSLLNILKEGKPIRVVLDVWENEPLICSKLLSLI--DIGTPHIAGHSLEGK 262 Query: 265 LRYAAGVKDMLDRYF--KGEEFPVENYI 188 ++ + + L + K +++ + ++I Sbjct: 263 IKGTISIFNSLCNFVGKKNKKYFISSFI 290
>PDXB_PHOPR (Q6LNU2) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| Length = 391 Score = 44.7 bits (104), Expect = 3e-04 Identities = 37/138 (26%), Positives = 66/138 (47%), Gaps = 8/138 (5%) Frame = -1 Query: 613 NPELEKEIGAKFEEDLDAMLPKCDVVVINTPLTE----KTRGMFNKEKIAKMKKGVIIVN 446 +P E+E + L+A+ +CDV+ ++TP+T+ T + N+ I ++ I++N Sbjct: 147 DPIKEQEGDTRQFHSLEAIKAQCDVITVHTPITKDGEYPTHHLINEAFIDALQPDAILIN 206 Query: 445 NARGAIMDTQAVADACSSGHIAGYGGDVWFPQPAPKDHP---WRYMPNHAM-TPHISGTT 278 ARG + D QA+ A +G G + + P +P A TPHI+G Sbjct: 207 AARGPVTDNQALKKALQLSQ-SGLGKKLTAVLDVFEFEPHVDLELLPLLAFATPHIAGYG 265 Query: 277 IDAQLRYAAGVKDMLDRY 224 ++ + R G + +RY Sbjct: 266 LEGKAR---GTTMVFNRY 280
>PDXB_BLOFL (Q7VRU9) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| Length = 372 Score = 42.4 bits (98), Expect = 0.001 Identities = 30/122 (24%), Positives = 56/122 (45%), Gaps = 4/122 (3%) Frame = -1 Query: 574 EDLDAMLPKCDVVVINTPLTEK----TRGMFNKEKIAKMKKGVIIVNNARGAIMDTQAVA 407 + LD ++ K D++ ++ PLT T M NK+ + + I++N +RGA+++ + Sbjct: 160 KSLDILVSKSDILTLHVPLTYTGAYPTWHMINKDILDALPSNSILINTSRGAVVNNDDLL 219 Query: 406 DACSSGHIAGYGGDVWFPQPAPKDHPWRYMPNHAMTPHISGTTIDAQLRYAAGVKDMLDR 227 G DVW +P Y+ T HI+G + ++++R + D Sbjct: 220 AILRCGKKINVILDVWESEPKLSLPLLSYV--DIGTAHIAGYSFESRIRSIKKIYDDYCD 277 Query: 226 YF 221 YF Sbjct: 278 YF 279
>PDXB_COXBU (Q83AR8) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| Length = 366 Score = 40.0 bits (92), Expect = 0.006 Identities = 32/118 (27%), Positives = 53/118 (44%), Gaps = 4/118 (3%) Frame = -1 Query: 562 AMLPKCDVVVINTPLTEK----TRGMFNKEKIAKMKKGVIIVNNARGAIMDTQAVADACS 395 A L D+V ++TPL + T + + + +K G +++N RGA++D A+ Sbjct: 163 ASLANVDLVCLHTPLVKTGNFPTYHLIDNRFLKMLKPGSVLLNAGRGAVIDNNALLQC-- 220 Query: 394 SGHIAGYGGDVWFPQPAPKDHPWRYMPNHAMTPHISGTTIDAQLRYAAGVKDMLDRYF 221 H+ DVW +P TPHI+G + A+LR + D +YF Sbjct: 221 -DHVITCL-DVWENEPTVNLQLLE--KTTIATPHIAGYSKQAKLRATLMIYDAFLKYF 274
>PDXB_ERWCT (Q6D2N5) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| Length = 378 Score = 40.0 bits (92), Expect = 0.006 Identities = 26/107 (24%), Positives = 49/107 (45%), Gaps = 4/107 (3%) Frame = -1 Query: 568 LDAMLPKCDVVVINTPL----TEKTRGMFNKEKIAKMKKGVIIVNNARGAIMDTQAVADA 401 L+ ++ D++ ++TPL +T + + + G I++N RG ++D A+ +A Sbjct: 161 LETLVRDADILTLHTPLYLDGPYRTHHLVDATVLNAFADGRILINACRGPVVDNAALLEA 220 Query: 400 CSSGHIAGYGGDVWFPQPAPKDHPWRYMPNHAMTPHISGTTIDAQLR 260 G DVW P+P + T HI+G T++ + R Sbjct: 221 LQQGKKLSVILDVWEPEPGLSTDLLARV--DIGTAHIAGYTLEGKAR 265
>PDXB_VIBCH (Q9KQ92) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| Length = 381 Score = 37.4 bits (85), Expect = 0.040 Identities = 27/109 (24%), Positives = 53/109 (48%), Gaps = 5/109 (4%) Frame = -1 Query: 571 DLDAMLPKCDVVVINTPLTE----KTRGMFNKEKIAKMKKGVIIVNNARGAIMDTQAVAD 404 +L+ +L + DV+ ++TP+T T + + + +++ I++N ARG ++D A+ Sbjct: 161 ELETLLKQADVITLHTPITRGGEWPTHHLIDAAILEQLRSDQILINAARGPVVDNAALKA 220 Query: 403 ACSSGHIAGYGGDVWFPQPAPKDHPWRYMPNHAM-TPHISGTTIDAQLR 260 G DV+ +P +P A TPHI+G ++ + R Sbjct: 221 RLQQGDGFTAVLDVFEFEP---QVDMELLPLLAFATPHIAGYGLEGKAR 266
>SYFA_MYCPE (Q8EUJ8) Phenylalanyl-tRNA synthetase alpha chain (EC 6.1.1.20)| (Phenylalanine--tRNA ligase alpha chain) (PheRS) Length = 341 Score = 32.0 bits (71), Expect = 1.7 Identities = 23/78 (29%), Positives = 38/78 (48%), Gaps = 2/78 (2%) Frame = +2 Query: 197 LHGELLALEVPIQHVLHSSRVPQLCINCSPRDVRGHCVIRHVAPWV-ILGCGLGEPDITS 373 L E + + I H + ++ INC D + HC + W+ +LG GL P++ Sbjct: 234 LFNESIKIRYRISHFPFTEPSFEVDINCFFCDSKDHCSVCKNTKWIEVLGAGLLHPNVLK 293 Query: 374 VSSNVTAGAS-ISNSLGI 424 ++NV G S I+ +GI Sbjct: 294 -NANVKKGLSGIAFGIGI 310
>MLZE_HUMAN (Q9BYG8) Melanoma-derived leucine zipper-containing extranuclear| factor Length = 508 Score = 32.0 bits (71), Expect = 1.7 Identities = 17/62 (27%), Positives = 28/62 (45%) Frame = -1 Query: 511 KTRGMFNKEKIAKMKKGVIIVNNARGAIMDTQAVADACSSGHIAGYGGDVWFPQPAPKDH 332 KT +K+ M ++ + RGA+ D + + SSGH+ G GG + +H Sbjct: 328 KTLAQLSKDVQDVMFYSILAMLRDRGALQDLMNMLELDSSGHLDGPGGAILKKLQQDSNH 387 Query: 331 PW 326 W Sbjct: 388 AW 389
>STA13_HUMAN (Q9Y3M8) StAR-related lipid transfer protein 13 (StARD13) (START| domain-containing protein 13) (46H23.2) (Deleted in liver cancer protein 2) (Rho GTPase-activating protein) Length = 1113 Score = 31.2 bits (69), Expect = 2.9 Identities = 15/55 (27%), Positives = 27/55 (49%) Frame = -1 Query: 553 PKCDVVVINTPLTEKTRGMFNKEKIAKMKKGVIIVNNARGAIMDTQAVADACSSG 389 P D VV+ T T+ +GM ++ + ++ R +MD+Q + + C SG Sbjct: 1008 PSRDFVVLRTWKTDLPKGMCTLVSLSVEHEEAQLLGGVRAVVMDSQYLIEPCGSG 1062
>NEUV_FUGRU (O42499) Vasotocin-neurophysin VT 1 precursor [Contains: Vasotocin| (VT); Neurophysin VT 1] Length = 153 Score = 30.4 bits (67), Expect = 4.9 Identities = 13/32 (40%), Positives = 19/32 (59%) Frame = +2 Query: 269 CINCSPRDVRGHCVIRHVAPWVILGCGLGEPD 364 C++C PRD RG C ++ LGC +G P+ Sbjct: 41 CMSCGPRD-RGRCFGPNICCGEALGCLMGSPE 71
>TALA_SALTY (Q8ZN83) Transaldolase A (EC 2.2.1.2)| Length = 316 Score = 30.4 bits (67), Expect = 4.9 Identities = 20/60 (33%), Positives = 34/60 (56%), Gaps = 3/60 (5%) Frame = -1 Query: 628 DRLQINPELEKEIGAKFEEDLDAMLPKCDVVVINTPLTE-KTRGMFNKEKIA--KMKKGV 458 DRL I+P L KE+ K E + ++P + TP+TE + R N++ +A K+ +G+ Sbjct: 239 DRLTISPNLLKELKEKEEPVIRKLVPSSQMFHRPTPMTEAEFRWEHNQDAMAVEKLSEGI 298
>TALA_SALTI (Q8Z4T0) Transaldolase A (EC 2.2.1.2)| Length = 316 Score = 30.4 bits (67), Expect = 4.9 Identities = 20/60 (33%), Positives = 34/60 (56%), Gaps = 3/60 (5%) Frame = -1 Query: 628 DRLQINPELEKEIGAKFEEDLDAMLPKCDVVVINTPLTE-KTRGMFNKEKIA--KMKKGV 458 DRL I+P L KE+ K E + ++P + TP+TE + R N++ +A K+ +G+ Sbjct: 239 DRLTISPNLLKELKEKEEPVIRKLVPSSQMFHRPTPMTEAEFRWEHNQDAMAVEKLSEGI 298
>TAL2_SALCH (Q57LN7) Transaldolase 2 (EC 2.2.1.2)| Length = 316 Score = 30.4 bits (67), Expect = 4.9 Identities = 20/60 (33%), Positives = 34/60 (56%), Gaps = 3/60 (5%) Frame = -1 Query: 628 DRLQINPELEKEIGAKFEEDLDAMLPKCDVVVINTPLTE-KTRGMFNKEKIA--KMKKGV 458 DRL I+P L KE+ K E + ++P + TP+TE + R N++ +A K+ +G+ Sbjct: 239 DRLTISPNLLKELKEKEEPVIRKLVPSSQMFHRPTPMTEAEFRWEHNQDAMAVEKLSEGI 298
>RFC1_MOUSE (P35601) Activator 1 140 kDa subunit (Replication factor C large| subunit) (A1 140 kDa subunit) (RF-C 140 kDa subunit) (Activator 1 large subunit) (A1-P145) (Differentiation-specific element-binding protein) (ISRE-binding protein) Length = 1131 Score = 30.0 bits (66), Expect = 6.5 Identities = 19/69 (27%), Positives = 32/69 (46%), Gaps = 4/69 (5%) Frame = -1 Query: 655 PFNCNLLYHDRLQINPELEKEIGAKFEEDLDAMLPKCDVVVINTPLTEKTR----GMFNK 488 P++ ++ RL P L+ E +F+ED + D V + + +KTR + Sbjct: 1058 PYSLQVVKTSRLSTGPALDSEYSEEFQEDDTQSEKEQDAVETDAMIKKKTRSSKPSKSER 1117 Query: 487 EKIAKMKKG 461 EK +K KG Sbjct: 1118 EKESKKGKG 1126
>RPOC_DESPS (Q6AP77) DNA-directed RNA polymerase beta' chain (EC 2.7.7.6) (RNAP| beta' subunit) (Transcriptase beta' chain) (RNA polymerase beta' subunit) Length = 1349 Score = 29.6 bits (65), Expect = 8.4 Identities = 26/86 (30%), Positives = 35/86 (40%), Gaps = 1/86 (1%) Frame = +2 Query: 164 AGELAFLDDVVLHGELLALEVPIQHVLHSSRVPQLCINCSPRDV-RGHCVIRHVAPWVIL 340 AGE D V + E V I+ VL +C C RD+ RGH + + A VI Sbjct: 847 AGEQMEEDKVAILEEAGIDRVMIRSVLTCRSKRGVCAACYGRDLGRGHLINQGEAVGVIA 906 Query: 341 GCGLGEPDITSVSSNVTAGASISNSL 418 +GEP G + S S+ Sbjct: 907 AQSIGEPGTQLTMRTFHIGGTASRSV 932
>STA13_MOUSE (Q923Q2) StAR-related lipid transfer protein 13 (StARD13) (START| domain-containing protein 13) Length = 1113 Score = 29.6 bits (65), Expect = 8.4 Identities = 14/55 (25%), Positives = 27/55 (49%) Frame = -1 Query: 553 PKCDVVVINTPLTEKTRGMFNKEKIAKMKKGVIIVNNARGAIMDTQAVADACSSG 389 P D +V+ T T+ +GM ++ + ++ R +MD+Q + + C SG Sbjct: 1008 PSRDFLVLRTWKTDLPKGMCTLVSLSVEYEEAQLMGGVRAVVMDSQYLIEPCGSG 1062
>NODU_BRAJA (P26027) Nodulation protein U (EC 2.1.3.-)| Length = 569 Score = 29.6 bits (65), Expect = 8.4 Identities = 16/38 (42%), Positives = 22/38 (57%), Gaps = 3/38 (7%) Frame = -1 Query: 262 RYAAGVKDMLDRY---FKGEEFPVENYIVKEGELASQY 158 R+A G+ D +D Y GEEFP ++Y G +AS Y Sbjct: 95 RHAEGLLDSVDGYGLLLGGEEFPYKSYPHVTGHVASAY 132
>MALR_STAXY (Q56201) HTH-type transcriptional regulator malR (Maltose operon| transcriptional repressor) Length = 337 Score = 29.6 bits (65), Expect = 8.4 Identities = 19/74 (25%), Positives = 39/74 (52%), Gaps = 2/74 (2%) Frame = +2 Query: 203 GELLALEVPIQHVLHSSRVPQLCINCSPRDVRGHCVIR-HVAPWVILGCGLGEPDITSV- 376 G+ + +E+ +Q ++H V + S + +++ H P+VI+G L + DI + Sbjct: 103 GQSIEIELEVQEMIHYHSVDGFIVLYSKKSDPIIDILKSHAMPYVIIGKPLTDDDIIHID 162 Query: 377 SSNVTAGASISNSL 418 + NV+A S++ L Sbjct: 163 NDNVSASQSLTRYL 176
>METE_SALTI (Q8Z3B6) 5-methyltetrahydropteroyltriglutamate--homocysteine| methyltransferase (EC 2.1.1.14) (Methionine synthase, vitamin-B12 independent isozyme) (Cobalamin-independent methionine synthase) Length = 753 Score = 29.6 bits (65), Expect = 8.4 Identities = 19/34 (55%), Positives = 20/34 (58%), Gaps = 3/34 (8%) Frame = +2 Query: 167 GELAFLDDVVLHGELLALE---VPIQHVLHSSRV 259 GELA L D + GE ALE VPIQ HS RV Sbjct: 353 GELALLRDALNSGETAALEEWSVPIQARRHSHRV 386 Database: uniprot_sprot.fasta Posted date: May 25, 2006 5:36 PM Number of letters in database: 80,573,946 Number of sequences in database: 219,361 Lambda K H 0.318 0.135 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 101,074,888 Number of Sequences: 219361 Number of extensions: 2215704 Number of successful extensions: 6566 Number of sequences better than 10.0: 126 Number of HSP's better than 10.0 without gapping: 6316 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 6525 length of database: 80,573,946 effective HSP length: 108 effective length of database: 56,882,958 effective search space used: 6370891296 frameshift window, decay const: 50, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
