ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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| Clone Name | rbasd25c22 |
|---|---|
| Clone Library Name | barley_pub |
>PBS1_ARATH (Q9FE20) Serine/threonine-protein kinase PBS1 (EC 2.7.11.1)| (AvrPphB susceptible protein 1) Length = 456 Score = 134 bits (336), Expect = 3e-31 Identities = 76/166 (45%), Positives = 102/166 (61%), Gaps = 1/166 (0%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRVLGTFGYHAPEYAMTGQLSSKSD 468 D KSSN+LL + K++DF L+ P STRV+GT+GY APEYAMTGQL+ KSD Sbjct: 213 DFKSSNILLDEGFHPKLSDFGLAKLGPTGDKSHVSTRVMGTYGYCAPEYAMTGQLTVKSD 272 Query: 467 VYSFGVVLLELLTGRKPVDHTLPRGQQSLVTWATPRLSE-DKVRQCVDSRLGGDYPPXXX 291 VYSFGVV LEL+TGRK +D +P G+Q+LV WA P ++ K + D RL G +P Sbjct: 273 VYSFGVVFLELITGRKAIDSEMPHGEQNLVAWARPLFNDRRKFIKLADPRLKGRFPTRAL 332 Query: 290 XXXXXXXALCVQYEADFRPNMSIVVKALQPLLNARAAHPGAEHAGR 153 ++C+Q +A RP ++ VV AL L N +A P + + R Sbjct: 333 YQALAVASMCIQEQAATRPLIADVVTALSYLAN-QAYDPSKDDSRR 377
>RLCK7_ARATH (Q9LQQ8) Probable serine/threonine-protein kinase RLCKVII (EC| 2.7.11.1) Length = 423 Score = 129 bits (323), Expect = 1e-29 Identities = 72/155 (46%), Positives = 97/155 (62%), Gaps = 1/155 (0%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRVLGTFGYHAPEYAMTGQLSSKSD 468 D+K SN+LL ++ K++DF L+ P STRV+GT+GY AP+YAMTGQL+ KSD Sbjct: 230 DLKCSNILLGEDYQPKLSDFGLAKVGPSGDKTHVSTRVMGTYGYCAPDYAMTGQLTFKSD 289 Query: 467 VYSFGVVLLELLTGRKPVDHTLPRGQQSLVTWATPRLSEDK-VRQCVDSRLGGDYPPXXX 291 +YSFGVVLLEL+TGRK +D+T R Q+LV WA P + + + VD L G YP Sbjct: 290 IYSFGVVLLELITGRKAIDNTKTRKDQNLVGWARPLFKDRRNFPKMVDPLLQGQYPVRGL 349 Query: 290 XXXXXXXALCVQYEADFRPNMSIVVKALQPLLNAR 186 A+CVQ + RP +S VV AL L +++ Sbjct: 350 YQALAISAMCVQEQPTMRPVVSDVVLALNFLASSK 384
>APK1A_ARATH (Q06548) Protein kinase APK1A, chloroplast precursor (EC 2.7.11.1)| Length = 410 Score = 127 bits (320), Expect = 2e-29 Identities = 73/160 (45%), Positives = 96/160 (60%), Gaps = 1/160 (0%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRVLGTFGYHAPEYAMTGQLSSKSD 468 D K+SN+LL E AK++DF L+ P STRV+GT GY APEY TG L++KSD Sbjct: 203 DFKTSNILLDSEYNAKLSDFGLAKDGPIGDKSHVSTRVMGTHGYAAPEYLATGHLTTKSD 262 Query: 467 VYSFGVVLLELLTGRKPVDHTLPRGQQSLVTWATPRL-SEDKVRQCVDSRLGGDYPPXXX 291 VYSFGVVLLELL+GR+ VD P G+++LV WA P L ++ K+ + +D+RL Y Sbjct: 263 VYSFGVVLLELLSGRRAVDKNRPSGERNLVEWAKPYLVNKRKIFRVIDNRLQDQYSMEEA 322 Query: 290 XXXXXXXALCVQYEADFRPNMSIVVKALQPLLNARAAHPG 171 C+ E RPNMS VV L+ + + AA G Sbjct: 323 CKVATLSLRCLTTEIKLRPNMSEVVSHLEHIQSLNAAIGG 362
>APK1B_ARATH (P46573) Protein kinase APK1B, chloroplast precursor (EC 2.7.11.1)| Length = 412 Score = 125 bits (314), Expect = 1e-28 Identities = 67/149 (44%), Positives = 92/149 (61%), Gaps = 1/149 (0%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRVLGTFGYHAPEYAMTGQLSSKSD 468 D K+SN+LL E AK++DF L+ P STR++GT+GY APEY TG L++KSD Sbjct: 204 DFKTSNILLDSEYNAKLSDFGLAKDGPTGDKSHVSTRIMGTYGYAAPEYLATGHLTTKSD 263 Query: 467 VYSFGVVLLELLTGRKPVDHTLPRGQQSLVTWATPRL-SEDKVRQCVDSRLGGDYPPXXX 291 VYS+GVVLLE+L+GR+ VD P G+Q LV WA P L ++ K+ + +D+RL Y Sbjct: 264 VYSYGVVLLEVLSGRRAVDKNRPPGEQKLVEWARPLLANKRKLFRVIDNRLQDQYSMEEA 323 Query: 290 XXXXXXXALCVQYEADFRPNMSIVVKALQ 204 C+ +E RPNM+ VV L+ Sbjct: 324 CKVATLALRCLTFEIKLRPNMNEVVSHLE 352
>NAK_ARATH (P43293) Probable serine/threonine-protein kinase NAK (EC 2.7.11.1)| Length = 389 Score = 120 bits (302), Expect = 3e-27 Identities = 69/152 (45%), Positives = 92/152 (60%), Gaps = 2/152 (1%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLH-STRVLGTFGYHAPEYAMTGQLSSKS 471 D K+SN+LL AK++DF L+ P M H STRV+GT GY APEY TG LS KS Sbjct: 203 DFKASNILLDSNYNAKLSDFGLARDGP-MGDNSHVSTRVMGTQGYAAPEYLATGHLSVKS 261 Query: 470 DVYSFGVVLLELLTGRKPVDHTLPRGQQSLVTWATPRL-SEDKVRQCVDSRLGGDYPPXX 294 DVYSFGVVLLELL+GR+ +D P G+ +LV WA P L ++ ++ + +D RL G Y Sbjct: 262 DVYSFGVVLLELLSGRRAIDKNQPVGEHNLVDWARPYLTNKRRLLRVMDPRLQGQYSLTR 321 Query: 293 XXXXXXXXALCVQYEADFRPNMSIVVKALQPL 198 C+ +A RP M+ +VK ++ L Sbjct: 322 ALKIAVLALDCISIDAKSRPTMNEIVKTMEEL 353
>CX32_ARATH (P27450) Probable serine/threonine-protein kinase Cx32, chloroplast| precursor (EC 2.7.11.1) Length = 419 Score = 112 bits (281), Expect = 8e-25 Identities = 61/149 (40%), Positives = 87/149 (58%), Gaps = 1/149 (0%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRVLGTFGYHAPEYAMTGQLSSKSD 468 D K+SN+LL AK++DF L+ P +TR++GT+GY APEY TG L KSD Sbjct: 218 DFKASNILLDSNYDAKLSDFGLAKLGPADEKSHVTTRIMGTYGYAAPEYMATGHLYVKSD 277 Query: 467 VYSFGVVLLELLTGRKPVDHTLPRGQQSLVTWATPRLS-EDKVRQCVDSRLGGDYPPXXX 291 V++FGVVLLE++TG + PRGQ+SLV W P LS + +V+Q +D + G Y Sbjct: 278 VFAFGVVLLEIMTGLTAHNTKRPRGQESLVDWLRPELSNKHRVKQIMDKGIKGQYTTKVA 337 Query: 290 XXXXXXXALCVQYEADFRPNMSIVVKALQ 204 C++ + RP+M VV+ L+ Sbjct: 338 TEMARITLSCIEPDPKNRPHMKEVVEVLE 366
>NORK_PEA (Q8LKZ1) Nodulation receptor kinase precursor (EC 2.7.11.1)| Length = 924 Score = 112 bits (281), Expect = 8e-25 Identities = 64/151 (42%), Positives = 85/151 (56%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRVLGTFGYHAPEYAMTGQLSSKSD 468 D+KSSN+LL AK+ADF S AP S V GT GY PEY T QLS KSD Sbjct: 721 DVKSSNILLDHSMCAKVADFGFSKYAPQEGDSYVSLEVRGTAGYLDPEYYKTQQLSEKSD 780 Query: 467 VYSFGVVLLELLTGRKPVDHTLPRGQQSLVTWATPRLSEDKVRQCVDSRLGGDYPPXXXX 288 V+SFGVVLLE+++GR+P++ PR + SLV WA P + KV + VD + G Y Sbjct: 781 VFSFGVVLLEIVSGREPLNIKRPRVEWSLVEWAKPYIRASKVDEIVDPGIKGGYHAEALW 840 Query: 287 XXXXXXALCVQYEADFRPNMSIVVKALQPLL 195 C++ + +RP M +V+ L+ L Sbjct: 841 RVVEVALQCLEPYSTYRPCMVDIVRELEDAL 871
>NORK_MEDTR (Q8L4H4) Nodulation receptor kinase precursor (EC 2.7.11.1) (Does not| make infections protein 2) (Symbiosis receptor-like kinase) (MtSYMRK) Length = 925 Score = 112 bits (281), Expect = 8e-25 Identities = 64/151 (42%), Positives = 85/151 (56%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRVLGTFGYHAPEYAMTGQLSSKSD 468 D+KSSN+LL AK+ADF S AP S V GT GY PEY T QLS KSD Sbjct: 722 DVKSSNILLDQSMCAKVADFGFSKYAPQEGDSYVSLEVRGTAGYLDPEYYKTQQLSEKSD 781 Query: 467 VYSFGVVLLELLTGRKPVDHTLPRGQQSLVTWATPRLSEDKVRQCVDSRLGGDYPPXXXX 288 V+SFGVVLLE+++GR+P++ PR + SLV WA P + KV + VD + G Y Sbjct: 782 VFSFGVVLLEIVSGREPLNIKRPRIEWSLVEWAKPYIRASKVDEIVDPGIKGGYHAEALW 841 Query: 287 XXXXXXALCVQYEADFRPNMSIVVKALQPLL 195 C++ + +RP M +V+ L+ L Sbjct: 842 RVVEVALQCLEPYSTYRPCMVDIVRELEDAL 872
>TMK1_ARATH (P43298) Putative receptor protein kinase TMK1 precursor (EC| 2.7.11.1) Length = 942 Score = 99.8 bits (247), Expect = 7e-21 Identities = 60/154 (38%), Positives = 85/154 (55%), Gaps = 3/154 (1%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRVLGTFGYHAPEYAMTGQLSSKSD 468 D+K SN+LL D+ AK+ADF L AP+ + TR+ GTFGY APEYA+TG++++K D Sbjct: 717 DLKPSNILLGDDMRAKVADFGLVRLAPEGKGSIE-TRIAGTFGYLAPEYAVTGRVTTKVD 775 Query: 467 VYSFGVVLLELLTGRKPVDHTLPRGQQSLVTWATPRL--SEDKVRQCVDSRLGGDYPP-X 297 VYSFGV+L+EL+TGRK +D + P LV+W E ++ +D+ + D Sbjct: 776 VYSFGVILMELITGRKSLDESQPEESIHLVSWFKRMYINKEASFKKAIDTTIDLDEETLA 835 Query: 296 XXXXXXXXXALCVQYEADFRPNMSIVVKALQPLL 195 C E RP+M V L L+ Sbjct: 836 SVHTVAELAGHCCAREPYQRPDMGHAVNILSSLV 869
>CLV1_ARATH (Q9SYQ8) Receptor protein kinase CLAVATA1 precursor (EC 2.7.11.1)| Length = 980 Score = 93.2 bits (230), Expect = 6e-19 Identities = 64/156 (41%), Positives = 85/156 (54%), Gaps = 9/156 (5%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRVLGTFGYHAPEYAMTGQLSSKSD 468 D+KS+N+LL + A +ADF L+ D AA + + G++GY APEYA T ++ KSD Sbjct: 817 DVKSNNILLDSDFEAHVADFGLAKFLVDGAASECMSSIAGSYGYIAPEYAYTLKVDEKSD 876 Query: 467 VYSFGVVLLELLTGRKPVDHTLPRGQQSLVTWATPRLSEDKVRQ---------CVDSRLG 315 VYSFGVVLLEL+ G+KPV G +V W R +E+++ Q VD RL Sbjct: 877 VYSFGVVLLELIAGKKPVGE-FGEG-VDIVRWV--RNTEEEITQPSDAAIVVAIVDPRLT 932 Query: 314 GDYPPXXXXXXXXXXALCVQYEADFRPNMSIVVKAL 207 G YP +CV+ EA RP M VV L Sbjct: 933 G-YPLTSVIHVFKIAMMCVEEEAAARPTMREVVHML 967
>CRI4_MAIZE (O24585) Putative receptor protein kinase CRINKLY4 precursor (EC| 2.7.11.1) Length = 901 Score = 91.7 bits (226), Expect = 2e-18 Identities = 59/161 (36%), Positives = 79/161 (49%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRVLGTFGYHAPEYAMTGQLSSKSD 468 DIKSSN+L+ ++ A++ADF LS P + S GT GY PEY L++KSD Sbjct: 634 DIKSSNILIDEDHNARVADFGLSILGPADSGTPLSELPAGTLGYLDPEYYRLHYLTTKSD 693 Query: 467 VYSFGVVLLELLTGRKPVDHTLPRGQQSLVTWATPRLSEDKVRQCVDSRLGGDYPPXXXX 288 VYSFGVVLLE+L+GRK +D G ++V WA P + + +D L Sbjct: 694 VYSFGVVLLEILSGRKAIDMQFEEG--NIVEWAVPLIKAGDIFAILDPVLSPPSDLEALK 751 Query: 287 XXXXXXALCVQYEADFRPNMSIVVKALQPLLNARAAHPGAE 165 CV+ RP+M V AL+ L P E Sbjct: 752 KIASVACKCVRMRGKDRPSMDKVTTALEHALALLMGSPCIE 792
>PSKR_DAUCA (Q8LPB4) Phytosulfokine receptor precursor (EC 2.7.11.1)| (Phytosulfokine LRR receptor kinase) Length = 1021 Score = 91.3 bits (225), Expect = 2e-18 Identities = 49/107 (45%), Positives = 65/107 (60%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRVLGTFGYHAPEYAMTGQLSSKSD 468 DIKSSN+LL D VA +ADF L+ + +T ++GT GY PEY + K D Sbjct: 869 DIKSSNILLSDTFVAHLADFGLARLILPYDTHV-TTDLVGTLGYIPPEYGQASVATYKGD 927 Query: 467 VYSFGVVLLELLTGRKPVDHTLPRGQQSLVTWATPRLSEDKVRQCVD 327 VYSFGVVLLELLTGR+P+D PRG + L++W +E + + D Sbjct: 928 VYSFGVVLLELLTGRRPMDVCKPRGSRDLISWVLQMKTEKRESEIFD 974
>EXS_ARATH (Q9LYN8) Leucine-rich repeat receptor protein kinase EXS precursor| (EC 2.7.11.1) (Extra sporogenous cells protein) (EXCESS MICROSPOROCYTES1 protein) Length = 1192 Score = 89.4 bits (220), Expect = 9e-18 Identities = 54/151 (35%), Positives = 81/151 (53%), Gaps = 1/151 (0%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRVLGTFGYHAPEYAMTGQLSSKSD 468 DIK+SN+LL + K+ADF L+ + + ST + GTFGY PEY + + ++K D Sbjct: 1043 DIKASNILLDGDFEPKVADFGLARLISACESHV-STVIAGTFGYIPPEYGQSARATTKGD 1101 Query: 467 VYSFGVVLLELLTGRKPVDHTLPRGQ-QSLVTWATPRLSEDKVRQCVDSRLGGDYPPXXX 291 VYSFGV+LLEL+TG++P + +LV WA ++++ K +D L Sbjct: 1102 VYSFGVILLELVTGKEPTGPDFKESEGGNLVGWAIQKINQGKAVDVIDPLLVSVALKNSQ 1161 Query: 290 XXXXXXXALCVQYEADFRPNMSIVVKALQPL 198 LC+ RPNM V+KAL+ + Sbjct: 1162 LRLLQIAMLCLAETPAKRPNMLDVLKALKEI 1192
>BAK1_ARATH (Q94F62) BRASSINOSTEROID INSENSITIVE 1-associated receptor kinase 1| precursor (EC 2.7.11.1) (BRI1-associated receptor kinase 1) (Somatic embryogenesis receptor-like kinase 3) Length = 615 Score = 87.0 bits (214), Expect = 5e-17 Identities = 55/150 (36%), Positives = 78/150 (52%), Gaps = 2/150 (1%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRVLGTFGYHAPEYAMTGQLSSKSD 468 D+K++N+LL +E A + DF L+ + D +T V GT G+ APEY TG+ S K+D Sbjct: 416 DVKAANILLDEEFEAVVGDFGLA-KLMDYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTD 474 Query: 467 VYSFGVVLLELLTGRKPVDHTLPRGQQS--LVTWATPRLSEDKVRQCVDSRLGGDYPPXX 294 V+ +GV+LLEL+TG++ D L+ W L E K+ VD L G+Y Sbjct: 475 VFGYGVMLLELITGQRAFDLARLANDDDVMLLDWVKGLLKEKKLEALVDVDLQGNYKDEE 534 Query: 293 XXXXXXXXALCVQYEADFRPNMSIVVKALQ 204 LC Q RP MS VV+ L+ Sbjct: 535 VEQLIQVALLCTQSSPMERPKMSEVVRMLE 564
>IRAK4_MOUSE (Q8R4K2) Interleukin-1 receptor-associated kinase 4 (EC 2.7.11.1)| (IRAK-4) Length = 459 Score = 85.5 bits (210), Expect = 1e-16 Identities = 53/150 (35%), Positives = 83/150 (55%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRVLGTFGYHAPEYAMTGQLSSKSD 468 DIKS+N+LL + AKI+DF L+ + +A + ++R++GT Y APE A+ G+++ KSD Sbjct: 311 DIKSANILLDKDFTAKISDFGLARASARLAQTVMTSRIVGTTAYMAPE-ALRGEITPKSD 369 Query: 467 VYSFGVVLLELLTGRKPVDHTLPRGQQSLVTWATPRLSEDKVRQCVDSRLGGDYPPXXXX 288 +YSFGVVLLEL+TG VD R Q L+ E+K + D P Sbjct: 370 IYSFGVVLLELITGLAAVDEN--REPQLLLDIKEEIEDEEKTIEDYTDEKMSDADPASVE 427 Query: 287 XXXXXXALCVQYEADFRPNMSIVVKALQPL 198 + C+ + + RP+++ V + LQ + Sbjct: 428 AMYSAASQCLHEKKNRRPDIAKVQQLLQEM 457
>PSKR_ARATH (Q9ZVR7) Putative phytosulfokine receptor precursor (EC 2.7.11.1)| (Phytosulfokine LRR receptor kinase) Length = 1008 Score = 84.3 bits (207), Expect = 3e-16 Identities = 45/107 (42%), Positives = 62/107 (57%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRVLGTFGYHAPEYAMTGQLSSKSD 468 DIKSSN+LL + + +ADF L+ + ST ++GT GY PEY + K D Sbjct: 860 DIKSSNILLDENFNSHLADFGLARLMSPYETHV-STDLVGTLGYIPPEYGQASVATYKGD 918 Query: 467 VYSFGVVLLELLTGRKPVDHTLPRGQQSLVTWATPRLSEDKVRQCVD 327 VYSFGVVLLELLT ++PVD P+G + L++W E + + D Sbjct: 919 VYSFGVVLLELLTDKRPVDMCKPKGCRDLISWVVKMKHESRASEVFD 965
>SRK6_BRAOE (Q09092) Putative serine/threonine-protein kinase receptor precursor| (EC 2.7.11.1) (S-receptor kinase) (SRK) Length = 849 Score = 83.2 bits (204), Expect = 7e-16 Identities = 52/151 (34%), Positives = 79/151 (52%), Gaps = 7/151 (4%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRVLGTFGYHAPEYAMTGQLSSKSD 468 D+K SN+LL + KI+DF ++ ++ +V+GT+GY +PEYAM G S KSD Sbjct: 653 DLKVSNILLDKNMIPKISDFGMARIFERDETEANTMKVVGTYGYMSPEYAMYGIFSEKSD 712 Query: 467 VYSFGVVLLELLTGRKPVDHTLPRGQQSLVTWATPRLSEDKVRQCVD-------SRLGGD 309 V+SFGV++LE+++G+K + L+++ R E + + VD S Sbjct: 713 VFSFGVIVLEIVSGKKNRGFYNLDYENDLLSYVWSRWKEGRALEIVDPVIVDSLSSQPSI 772 Query: 308 YPPXXXXXXXXXXALCVQYEADFRPNMSIVV 216 + P LCVQ A+ RP MS VV Sbjct: 773 FQPQEVLKCIQIGLLCVQELAEHRPAMSSVV 803
>BRL3_ARATH (Q9LJF3) Serine/threonine-protein kinase BRI1-like 3 precursor (EC| 2.7.11.1) (BRASSINOSTEROID INSENSITIVE 1-like protein 3) Length = 1164 Score = 81.6 bits (200), Expect = 2e-15 Identities = 44/113 (38%), Positives = 67/113 (59%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRVLGTFGYHAPEYAMTGQLSSKSD 468 D+KSSNVLL + VA+++DF ++ + L + + GT GY PEY + + ++K D Sbjct: 985 DMKSSNVLLDQDFVARVSDFGMARLVSALDTHLSVSTLAGTPGYVPPEYYQSFRCTAKGD 1044 Query: 467 VYSFGVVLLELLTGRKPVDHTLPRGQQSLVTWATPRLSEDKVRQCVDSRLGGD 309 VYS+GV+LLELL+G+KP+D +LV WA E + + +D L D Sbjct: 1045 VYSYGVILLELLSGKKPIDPEEFGEDNNLVGWAKQLYREKRGAEILDPELVTD 1097
>RLK5_ARATH (P47735) Receptor-like protein kinase 5 precursor (EC 2.7.11.1)| Length = 999 Score = 80.9 bits (198), Expect = 3e-15 Identities = 53/155 (34%), Positives = 79/155 (50%), Gaps = 2/155 (1%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTR--VLGTFGYHAPEYAMTGQLSSK 474 D+KSSN+LL + AK+ADF ++ ++ + G+ GY APEY T +++ K Sbjct: 819 DVKSSNILLDSDYGAKVADFGIAKVGQMSGSKTPEAMSGIAGSCGYIAPEYVYTLRVNEK 878 Query: 473 SDVYSFGVVLLELLTGRKPVDHTLPRGQQSLVTWATPRLSEDKVRQCVDSRLGGDYPPXX 294 SD+YSFGVVLLEL+TG++P D L G + + W L + + +D +L + Sbjct: 879 SDIYSFGVVLLELVTGKQPTDSEL--GDKDMAKWVCTALDKCGLEPVIDPKLDLKF-KEE 935 Query: 293 XXXXXXXXALCVQYEADFRPNMSIVVKALQPLLNA 189 LC RP+M VV LQ + A Sbjct: 936 ISKVIHIGLLCTSPLPLNRPSMRKVVIMLQEVSGA 970
>SIRK_ARATH (O64483) Senescence-induced receptor-like serine/threonine-protein| kinase precursor (FLG22-induced receptor-like kinase 1) Length = 876 Score = 80.5 bits (197), Expect = 4e-15 Identities = 53/151 (35%), Positives = 77/151 (50%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRVLGTFGYHAPEYAMTGQLSSKSD 468 D+K +N+LL ++ AK+ADF LS + ST V G+ GY PEY T Q++ KSD Sbjct: 697 DVKPTNILLNEKLQAKMADFGLSRSFSVEGSGQISTVVAGSIGYLDPEYYSTRQMNEKSD 756 Query: 467 VYSFGVVLLELLTGRKPVDHTLPRGQQSLVTWATPRLSEDKVRQCVDSRLGGDYPPXXXX 288 VYS GVVLLE++TG +P + + + L+ +R VD RL Y Sbjct: 757 VYSLGVVLLEVITG-QPAIASSKTEKVHISDHVRSILANGDIRGIVDQRLRERYDVGSAW 815 Query: 287 XXXXXXALCVQYEADFRPNMSIVVKALQPLL 195 C ++ + RP MS VV L+ ++ Sbjct: 816 KMSEIALACTEHTSAQRPTMSQVVMELKQIV 846
>IRAK4_HUMAN (Q9NWZ3) Interleukin-1 receptor-associated kinase 4 (EC 2.7.11.1)| (IRAK-4) (NY-REN-64 antigen) Length = 460 Score = 80.1 bits (196), Expect = 6e-15 Identities = 52/151 (34%), Positives = 84/151 (55%), Gaps = 1/151 (0%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRVLGTFGYHAPEYAMTGQLSSKSD 468 DIKS+N+LL + AKI+DF L+ + A + ++R++GT Y APE A+ G+++ KSD Sbjct: 311 DIKSANILLDEAFTAKISDFGLARASEKFAQTVMTSRIVGTTAYMAPE-ALRGEITPKSD 369 Query: 467 VYSFGVVLLELLTGRKPVDHTLPRGQQSLVTWATPRLSEDK-VRQCVDSRLGGDYPPXXX 291 +YSFGVVLLE++TG VD R Q L+ E+K + +D ++ D Sbjct: 370 IYSFGVVLLEIITGLPAVDE--HREPQLLLDIKEEIEDEEKTIEDYIDKKM-NDADSTSV 426 Query: 290 XXXXXXXALCVQYEADFRPNMSIVVKALQPL 198 + C+ + + RP++ V + LQ + Sbjct: 427 EAMYSVASQCLHEKKNKRPDIKKVQQLLQEM 457
>BRL1_ARATH (Q9ZWC8) Serine/threonine-protein kinase BRI1-like 1 precursor (EC| 2.7.11.1) (BRASSINOSTEROID INSENSITIVE 1-like protein 1) Length = 1166 Score = 79.7 bits (195), Expect = 7e-15 Identities = 43/113 (38%), Positives = 67/113 (59%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRVLGTFGYHAPEYAMTGQLSSKSD 468 D+KSSNVLL ++ A+++DF ++ + L + + GT GY PEY + + ++K D Sbjct: 987 DMKSSNVLLDEDFEARVSDFGMARLVSALDTHLSVSTLAGTPGYVPPEYYQSFRCTAKGD 1046 Query: 467 VYSFGVVLLELLTGRKPVDHTLPRGQQSLVTWATPRLSEDKVRQCVDSRLGGD 309 VYS+GV+LLELL+G+KP+D +LV WA E + + +D L D Sbjct: 1047 VYSYGVILLELLSGKKPIDPGEFGEDNNLVGWAKQLYREKRGAEILDPELVTD 1099
>RPK1_IPONI (P93194) Receptor-like protein kinase precursor (EC 2.7.11.1)| Length = 1109 Score = 77.0 bits (188), Expect = 5e-14 Identities = 53/152 (34%), Positives = 75/152 (49%), Gaps = 5/152 (3%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRVLGTFGYHAPEYAMTGQLSSKSD 468 DIK N+LL + I+DF ++ A + S V GT GY APE A T S +SD Sbjct: 942 DIKPMNILLDSDLEPHISDFGIAKLLDQSATSIPSNTVQGTIGYMAPENAFTTVKSRESD 1001 Query: 467 VYSFGVVLLELLTGRKPVDHTLPRGQQSLVTWATPRLSE-DKVRQCVDSRLGGDYPPXX- 294 VYS+GVVLLEL+T +K +D + G+ +V W ++ ++++ VD L + Sbjct: 1002 VYSYGVVLLELITRKKALDPSF-NGETDIVGWVRSVWTQTGEIQKIVDPSLLDELIDSSV 1060 Query: 293 ---XXXXXXXXALCVQYEADFRPNMSIVVKAL 207 C + E D RP M VVK L Sbjct: 1061 MEQVTEALSLALRCAEKEVDKRPTMRDVVKQL 1092
>BRI1_LYCPE (Q8L899) Systemin receptor SR160 precursor (EC 2.7.11.1)| (Brassinosteroid LRR receptor kinase) Length = 1207 Score = 77.0 bits (188), Expect = 5e-14 Identities = 42/92 (45%), Positives = 59/92 (64%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRVLGTFGYHAPEYAMTGQLSSKSD 468 D+KSSNVLL + A+++DF ++ M L + + GT GY PEY + + S+K D Sbjct: 1014 DMKSSNVLLDENLEARVSDFGMARLMSAMDTHLSVSTLAGTPGYVPPEYYQSFRCSTKGD 1073 Query: 467 VYSFGVVLLELLTGRKPVDHTLPRGQQSLVTW 372 VYS+GVVLLELLTG++P D + G +LV W Sbjct: 1074 VYSYGVVLLELLTGKQPTD-SADFGDNNLVGW 1104
>BRI1_LYCES (Q8GUQ5) Brassinosteroid LRR receptor kinase precursor (EC 2.7.11.1)| (tBRI1) (Altered brassinolide sensitivity 1) (Systemin receptor SR160) Length = 1207 Score = 77.0 bits (188), Expect = 5e-14 Identities = 42/92 (45%), Positives = 59/92 (64%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRVLGTFGYHAPEYAMTGQLSSKSD 468 D+KSSNVLL + A+++DF ++ M L + + GT GY PEY + + S+K D Sbjct: 1014 DMKSSNVLLDENLEARVSDFGMARLMSAMDTHLSVSTLAGTPGYVPPEYYQSFRCSTKGD 1073 Query: 467 VYSFGVVLLELLTGRKPVDHTLPRGQQSLVTW 372 VYS+GVVLLELLTG++P D + G +LV W Sbjct: 1074 VYSYGVVLLELLTGKQPTD-SADFGDNNLVGW 1104
>BRI1_ARATH (O22476) BRASSINOSTEROID INSENSITIVE 1 precursor (EC 2.7.11.1)| (AtBRI1) (Brassinosteroid LRR receptor kinase) Length = 1196 Score = 76.6 bits (187), Expect = 6e-14 Identities = 42/92 (45%), Positives = 59/92 (64%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRVLGTFGYHAPEYAMTGQLSSKSD 468 D+KSSNVLL + A+++DF ++ M L + + GT GY PEY + + S+K D Sbjct: 1009 DMKSSNVLLDENLEARVSDFGMARLMSAMDTHLSVSTLAGTPGYVPPEYYQSFRCSTKGD 1068 Query: 467 VYSFGVVLLELLTGRKPVDHTLPRGQQSLVTW 372 VYS+GVVLLELLTG++P D + G +LV W Sbjct: 1069 VYSYGVVLLELLTGKRPTD-SPDFGDNNLVGW 1099
>BRL2_ARATH (Q9ZPS9) Serine/threonine-protein kinase BRI1-like 2 precursor (EC| 2.7.11.1) (BRASSINOSTEROID INSENSITIVE 1-like protein 2) (Protein VASCULAR HIGHWAY 1) Length = 1143 Score = 75.9 bits (185), Expect = 1e-13 Identities = 41/110 (37%), Positives = 65/110 (59%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRVLGTFGYHAPEYAMTGQLSSKSD 468 D+KSSNVLL + A+++DF ++ + L + + GT GY PEY + + ++K D Sbjct: 966 DMKSSNVLLDQDMEARVSDFGMARLISALDTHLSVSTLAGTPGYVPPEYYQSFRCTAKGD 1025 Query: 467 VYSFGVVLLELLTGRKPVDHTLPRGQQSLVTWATPRLSEDKVRQCVDSRL 318 VYS GVV+LE+L+G++P D G +LV W+ + E K + +D L Sbjct: 1026 VYSIGVVMLEILSGKRPTDKE-EFGDTNLVGWSKMKAREGKHMEVIDEDL 1074
>PKN5_MYXXA (P54737) Serine/threonine-protein kinase pkn5 (EC 2.7.11.1)| Length = 380 Score = 66.6 bits (161), Expect = 6e-11 Identities = 32/83 (38%), Positives = 51/83 (61%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRVLGTFGYHAPEYAMTGQLSSKSD 468 D+K SN+++ D+ ++ DF L+ D AA + +++GT+ Y APE + L ++D Sbjct: 244 DLKPSNIMVDDDRQVRLMDFGLAKFLADDAAITEAGKLVGTYRYMAPEQILGEPLDGRAD 303 Query: 467 VYSFGVVLLELLTGRKPVDHTLP 399 +YS GV+L ELL+GR P D P Sbjct: 304 LYSLGVILYELLSGRPPFDAKTP 326
>IRAK1_HUMAN (P51617) Interleukin-1 receptor-associated kinase 1 (EC 2.7.11.1)| (IRAK-1) Length = 712 Score = 66.2 bits (160), Expect = 8e-11 Identities = 61/206 (29%), Positives = 86/206 (41%), Gaps = 34/206 (16%) Frame = -2 Query: 650 GDIKSSNVLLFDEDVAKIADFDLSN------QAPDMAARLHSTR-VLGTFGYHAPEYAMT 492 GDIKSSNVLL + K+ DF L+ +P ++ + T+ V GT Y EY T Sbjct: 339 GDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKT 398 Query: 491 GQLSSKSDVYSFGVVLLELLTGRKPVD--------------------HTLPRGQQSLV-- 378 G+L+ +D +SFGVV+LE L G++ V R QS + Sbjct: 399 GRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQA 458 Query: 377 -----TWATPRLSEDKVRQCVDSRLGGDYPPXXXXXXXXXXALCVQYEADFRPNMSIVVK 213 WA P ++ ++ +D R G PP C+ A RP M+ V + Sbjct: 459 GLAADAWAAP-IAMQIYKKHLDPR-PGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYE 516 Query: 212 ALQPLLNARAAHPGAEHAGR*APVGP 135 L+ L A PG A P P Sbjct: 517 RLEKLQAVVAGVPGHSEAASCIPPSP 542
>IRAK1_MOUSE (Q62406) Interleukin-1 receptor-associated kinase 1 (EC 2.7.11.1)| (IRAK-1) (IRAK) (Pelle-like protein kinase) (mPLK) Length = 710 Score = 65.9 bits (159), Expect = 1e-10 Identities = 56/185 (30%), Positives = 82/185 (44%), Gaps = 34/185 (18%) Frame = -2 Query: 650 GDIKSSNVLLFDEDVAKIADFDLSN-------QAPDMAARLHSTRVLGTFGYHAPEYAMT 492 GDIKSSNVLL + + K+ DF L+ +A + ++ V GT Y EY T Sbjct: 339 GDIKSSNVLLDERLMPKLGDFGLARFSRFAGAKASQSSTVARTSTVRGTLAYLPEEYIKT 398 Query: 491 GQLSSKSDVYSFGVVLLELLTGRKPV-----------DHTLPRGQQSLVT---------- 375 G+L+ +D +SFGVV+LE L G++ V D +++ VT Sbjct: 399 GRLAVDTDTFSFGVVILETLAGQRAVRTQGAKTKYLKDLIEDEAEEAGVTLKSTQPTLWV 458 Query: 374 ------WATPRLSEDKVRQCVDSRLGGDYPPXXXXXXXXXXALCVQYEADFRPNMSIVVK 213 WA P ++ ++ +DSR G PP C+ A RP M+ V K Sbjct: 459 GVATDAWAAP-IAAQIYKKHLDSR-PGPCPPQLGLALAQLACCCMHRRAKKRPPMTQVYK 516 Query: 212 ALQPL 198 L+ L Sbjct: 517 RLEGL 521
>PKN1_THETN (Q8R9T6) Probable serine/threonine-protein kinase Sps1 (EC| 2.7.11.1) Length = 625 Score = 65.9 bits (159), Expect = 1e-10 Identities = 33/83 (39%), Positives = 52/83 (62%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRVLGTFGYHAPEYAMTGQLSSKSD 468 DIK N+L+ DEDV K+ DF ++ +A + A ++ V+GT Y +PE A + ++D Sbjct: 134 DIKPQNILVTDEDVVKVTDFGIA-RAANGATITYTGDVIGTAYYFSPEQAKGSIVDERTD 192 Query: 467 VYSFGVVLLELLTGRKPVDHTLP 399 +YS G+VL E+LTG+ P + P Sbjct: 193 IYSLGIVLFEMLTGKVPFEGDSP 215
>KPEL_DROME (Q05652) Probable serine/threonine-protein kinase pelle (EC| 2.7.11.1) Length = 501 Score = 62.8 bits (151), Expect = 9e-10 Identities = 47/157 (29%), Positives = 78/157 (49%), Gaps = 5/157 (3%) Frame = -2 Query: 650 GDIKSSNVLLFDEDVAKIADFDLSNQAP-DMAARLHSTRVLGTFGYHAPEYAMTGQLSSK 474 GDIK +N+LL KI DF L + P + A + +V GT Y PE+ QLS+ Sbjct: 345 GDIKPANILLDQCLQPKIGDFGLVREGPKSLDAVVEVNKVFGTKIYLPPEFRNFRQLSTG 404 Query: 473 SDVYSFGVVLLELLTGRKPVDHTLPRGQ--QSLVTWATPRLSEDKVRQCVDSRLGGDYPP 300 DVYSFG+VLLE+ TGR+ D +P + ++L+ + + ++++ + ++ L Sbjct: 405 VDVYSFGIVLLEVFTGRQVTDR-VPENETKKNLLDYVKQQWRQNRM-ELLEKHLAAPMGK 462 Query: 299 XXX--XXXXXXXALCVQYEADFRPNMSIVVKALQPLL 195 C + RP+M+ V+K +P + Sbjct: 463 ELDMCMCAIEAGLHCTALDPQDRPSMNAVLKRFEPFV 499
>PKN2_CLOAB (Q97IC2) Probable serine/threonine protein kinase CAC1728 (EC| 2.7.11.1) Length = 657 Score = 61.6 bits (148), Expect = 2e-09 Identities = 29/83 (34%), Positives = 52/83 (62%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRVLGTFGYHAPEYAMTGQLSSKSD 468 DIK N+++ D+D+ K+ DF ++ +A + + + +V+G+ Y +PE A + ++D Sbjct: 133 DIKPHNIMVTDDDIIKVTDFGIA-KASNESTITTTNKVVGSAHYLSPEQAQGIPVDCRTD 191 Query: 467 VYSFGVVLLELLTGRKPVDHTLP 399 +YSFG+VL E+ TG+ P D P Sbjct: 192 IYSFGIVLYEMATGKVPYDADTP 214
>KPRO_MAIZE (P17801) Putative receptor protein kinase ZmPK1 precursor (EC| 2.7.11.1) Length = 817 Score = 61.6 bits (148), Expect = 2e-09 Identities = 47/161 (29%), Positives = 74/161 (45%), Gaps = 8/161 (4%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRVLGTFGYHAPEYAMTGQLSSKSD 468 D+K N+LL KI DF L + + + V GT GY APE+ + +++K D Sbjct: 658 DVKPENILLDQAFEPKITDFGLVKLLNRGGSTQNVSHVRGTLGYIAPEWVSSLPITAKVD 717 Query: 467 VYSFGVVLLELLTGRKPVD--------HTLPRGQQSLVTWATPRLSEDKVRQCVDSRLGG 312 VYS+GVVLLELLTG + + H++ R +++ + + +DS+L Sbjct: 718 VYSYGVVLLELLTGTRVSELVGGTDEVHSMLRKLVRMLSAKLEGEEQSWIDGYLDSKLNR 777 Query: 311 DYPPXXXXXXXXXXALCVQYEADFRPNMSIVVKALQPLLNA 189 C++ + RP M A+Q LL+A Sbjct: 778 PVNYVQARTLIKLAVSCLEEDRSKRPTME---HAVQTLLSA 815
>PKNB_BIFLO (Q8G6P9) Probable serine/threonine-protein kinase pknB (EC| 2.7.11.1) Length = 690 Score = 61.6 bits (148), Expect = 2e-09 Identities = 37/98 (37%), Positives = 54/98 (55%), Gaps = 3/98 (3%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARL-HSTRVLGTFGYHAPEYAMTGQLSSKS 471 DIK N+++ ++ V K+ DF ++ D AA + S V+GT Y +PE A + +S Sbjct: 146 DIKPGNIMISEQGVVKVMDFGIARALDDSAATMTQSQGVVGTAQYLSPEQARGETVDMRS 205 Query: 470 DVYSFGVVLLELLTGRKPV--DHTLPRGQQSLVTWATP 363 D+YS G VL E+LTGR P D + Q + ATP Sbjct: 206 DLYSAGCVLYEMLTGRPPFTGDSAVAIAYQHVSEVATP 243
>M3K12_HUMAN (Q12852) Mitogen-activated protein kinase kinase kinase 12 (EC| 2.7.11.25) (Mixed lineage kinase) (Leucine-zipper protein kinase) (ZPK) (Dual leucine zipper bearing kinase) (DLK) (MAPK-upstream kinase) (MUK) Length = 859 Score = 60.8 bits (146), Expect = 3e-09 Identities = 33/77 (42%), Positives = 46/77 (59%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRVLGTFGYHAPEYAMTGQLSSKSD 468 D+KS N+L+ +DV KI+DF S + D + ++ GT + APE +S K D Sbjct: 236 DLKSPNMLITYDDVVKISDFGTSKELSDKSTKMSFA---GTVAWMAPEVIRNEPVSEKVD 292 Query: 467 VYSFGVVLLELLTGRKP 417 ++SFGVVL ELLTG P Sbjct: 293 IWSFGVVLWELLTGEIP 309
>M3K12_RAT (Q63796) Mitogen-activated protein kinase kinase kinase 12 (EC| 2.7.11.25) (Mixed lineage kinase) (Leucine-zipper protein kinase) (ZPK) (Dual leucine zipper bearing kinase) (DLK) (MAPK-upstream kinase) (MUK) Length = 888 Score = 60.8 bits (146), Expect = 3e-09 Identities = 33/77 (42%), Positives = 46/77 (59%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRVLGTFGYHAPEYAMTGQLSSKSD 468 D+KS N+L+ +DV KI+DF S + D + ++ GT + APE +S K D Sbjct: 269 DLKSPNMLITYDDVVKISDFGTSKELSDKSTKMSFA---GTVAWMAPEVIRNEPVSEKVD 325 Query: 467 VYSFGVVLLELLTGRKP 417 ++SFGVVL ELLTG P Sbjct: 326 IWSFGVVLWELLTGEIP 342
>M3K12_MOUSE (Q60700) Mitogen-activated protein kinase kinase kinase 12 (EC| 2.7.11.25) (Mixed lineage kinase) (Leucine-zipper protein kinase) (ZPK) (Dual leucine zipper bearing kinase) (DLK) (MAPK-upstream kinase) (MUK) Length = 888 Score = 60.8 bits (146), Expect = 3e-09 Identities = 33/77 (42%), Positives = 46/77 (59%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRVLGTFGYHAPEYAMTGQLSSKSD 468 D+KS N+L+ +DV KI+DF S + D + ++ GT + APE +S K D Sbjct: 269 DLKSPNMLITYDDVVKISDFGTSKELSDKSTKMSFA---GTVAWMAPEVIRNEPVSEKVD 325 Query: 467 VYSFGVVLLELLTGRKP 417 ++SFGVVL ELLTG P Sbjct: 326 IWSFGVVLWELLTGEIP 342
>PKN2_BACSU (O34507) Probable serine/threonine-protein kinase yloP (EC| 2.7.11.1) Length = 648 Score = 60.5 bits (145), Expect = 5e-09 Identities = 33/79 (41%), Positives = 45/79 (56%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRVLGTFGYHAPEYAMTGQLSSKSD 468 DIK N+L+ K+ DF ++ A H+ VLG+ Y +PE A G + KSD Sbjct: 134 DIKPHNILIDHMGNIKVTDFGIAT-ALSSTTITHTNSVLGSVHYLSPEQARGGLATKKSD 192 Query: 467 VYSFGVVLLELLTGRKPVD 411 +Y+ G+VL ELLTGR P D Sbjct: 193 IYALGIVLFELLTGRIPFD 211
>IRAK3_MOUSE (Q8K4B2) Interleukin-1 receptor-associated kinase 3 (EC 2.7.11.1)| (IRAK-3) (IL-1 receptor-associated kinase M) (IRAK-M) Length = 609 Score = 60.1 bits (144), Expect = 6e-09 Identities = 44/154 (28%), Positives = 73/154 (47%), Gaps = 5/154 (3%) Frame = -2 Query: 650 GDIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRVLGT----FGYHAPEYAMTGQL 483 G++ S+N+LL D+ K+ DF ++ P++ + + + G Y EY G+L Sbjct: 305 GNVSSANILLDDQLQPKLTDFAAAHFRPNLEQQSSTINMTGGGRKHLWYMPEEYIRQGRL 364 Query: 482 SSKSDVYSFGVVLLELLTGRKPV-DHTLPRGQQSLVTWATPRLSEDKVRQCVDSRLGGDY 306 S K+DVYSFG+V++E+LTG K V D + L+ + D +D ++ Sbjct: 365 SVKTDVYSFGIVIMEVLTGCKVVLDDPKHVQLRDLLMELMEKRGLDSCLSFLDRKI-PPC 423 Query: 305 PPXXXXXXXXXXALCVQYEADFRPNMSIVVKALQ 204 P CV +A RP M V+ +L+ Sbjct: 424 PRNFSAKLFSLAGRCVATKAKLRPTMDEVLSSLE 457
>M3K13_HUMAN (O43283) Mitogen-activated protein kinase kinase kinase 13 (EC| 2.7.11.25) (Mixed lineage kinase) (MLK) (Leucine zipper-bearing kinase) Length = 966 Score = 59.7 bits (143), Expect = 8e-09 Identities = 33/77 (42%), Positives = 44/77 (57%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRVLGTFGYHAPEYAMTGQLSSKSD 468 D+KS NVL+ D KI+DF S + D + ++ GT + APE +S K D Sbjct: 279 DLKSPNVLVTHTDAVKISDFGTSKELSDKSTKMSFA---GTVAWMAPEVIRNEPVSEKVD 335 Query: 467 VYSFGVVLLELLTGRKP 417 ++SFGVVL ELLTG P Sbjct: 336 IWSFGVVLWELLTGEIP 352
>PKNL_MYCTU (O53510) Probable serine/threonine-protein kinase pknL (EC| 2.7.11.1) Length = 399 Score = 59.7 bits (143), Expect = 8e-09 Identities = 35/78 (44%), Positives = 45/78 (57%), Gaps = 1/78 (1%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRV-LGTFGYHAPEYAMTGQLSSKS 471 D+K N+L+ D+ K+ADF L AA + ST V LGT Y +PE G +S Sbjct: 142 DVKPENILISDDGDVKLADFGLVRAVA--AASITSTGVILGTAAYLSPEQVRDGNADPRS 199 Query: 470 DVYSFGVVLLELLTGRKP 417 DVYS GV++ ELLTG P Sbjct: 200 DVYSVGVLVYELLTGHTP 217
>PKNL_MYCBO (Q7TYY6) Probable serine/threonine-protein kinase pknL (EC| 2.7.11.1) Length = 399 Score = 59.7 bits (143), Expect = 8e-09 Identities = 35/78 (44%), Positives = 45/78 (57%), Gaps = 1/78 (1%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRV-LGTFGYHAPEYAMTGQLSSKS 471 D+K N+L+ D+ K+ADF L AA + ST V LGT Y +PE G +S Sbjct: 142 DVKPENILISDDGDVKLADFGLVRAVA--AASITSTGVILGTAAYLSPEQVRDGNADPRS 199 Query: 470 DVYSFGVVLLELLTGRKP 417 DVYS GV++ ELLTG P Sbjct: 200 DVYSVGVLVYELLTGHTP 217
>PK1_STRTO (Q9KIG4) Serine/threonine-protein kinase PK-1 (EC 2.7.11.1)| (stoPK-1) Length = 641 Score = 59.3 bits (142), Expect = 1e-08 Identities = 36/83 (43%), Positives = 46/83 (55%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRVLGTFGYHAPEYAMTGQLSSKSD 468 D+K NVL+ D+ K+ADF L +A D T VLGT Y APE G + D Sbjct: 141 DMKPENVLIGDDGRVKVADFGLV-RAVDSVTNTTGT-VLGTVSYLAPEQIEHGTADPRVD 198 Query: 467 VYSFGVVLLELLTGRKPVDHTLP 399 VY+ G++L E+LTG KP D P Sbjct: 199 VYACGILLYEMLTGEKPHDGDSP 221
>M3K13_PONPY (Q5R8X7) Mitogen-activated protein kinase kinase kinase 13 (EC| 2.7.11.25) Length = 966 Score = 59.3 bits (142), Expect = 1e-08 Identities = 33/77 (42%), Positives = 44/77 (57%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRVLGTFGYHAPEYAMTGQLSSKSD 468 D+KS NVL+ D KI+DF S + D + ++ GT + APE +S K D Sbjct: 279 DLKSPNVLVTHTDAVKISDFGTSKELSDKSTKMSFA---GTVAWLAPEVIRNEPVSEKVD 335 Query: 467 VYSFGVVLLELLTGRKP 417 ++SFGVVL ELLTG P Sbjct: 336 IWSFGVVLWELLTGEIP 352
>PKNB_MYCLE (P54744) Probable serine/threonine-protein kinase pknB (EC| 2.7.11.1) Length = 622 Score = 58.9 bits (141), Expect = 1e-08 Identities = 27/77 (35%), Positives = 44/77 (57%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRVLGTFGYHAPEYAMTGQLSSKSD 468 D+K +N+++ + K+ DF ++ D + + V+GT Y +PE A + ++SD Sbjct: 138 DVKPANIMISATNAVKVMDFGIARAIADSTSVTQTAAVIGTAQYLSPEQARGDSVDARSD 197 Query: 467 VYSFGVVLLELLTGRKP 417 VYS G VL E+LTG P Sbjct: 198 VYSLGCVLYEILTGEPP 214
>MOS_MSVTS (P10421) Serine/threonine-protein kinase transforming protein mos| (EC 2.7.11.1) Length = 342 Score = 58.9 bits (141), Expect = 1e-08 Identities = 27/77 (35%), Positives = 45/77 (58%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRVLGTFGYHAPEYAMTGQLSSKSD 468 D+K +N+L+ ++DV KI+DF S + D+ R + GT+ + APE + K+D Sbjct: 198 DLKPANILISEQDVCKISDFGCSQKLQDLRCRQSPHHIGGTYTHQAPEILKGEIATPKAD 257 Query: 467 VYSFGVVLLELLTGRKP 417 +YSFG+ L ++ T P Sbjct: 258 IYSFGITLWQMTTREVP 274
>NRKA_TRYBB (Q08942) Putative serine/threonine-protein kinase A (EC 2.7.11.1)| Length = 431 Score = 58.2 bits (139), Expect = 2e-08 Identities = 39/117 (33%), Positives = 60/117 (51%), Gaps = 4/117 (3%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRVLGTFGYHAPEYAMTGQLSSKSD 468 DIKS+NVLL + K+ DF S+Q D + + ++ GT Y APE + + K+D Sbjct: 147 DIKSANVLLTSTGLVKLGDFGFSHQYEDTVSGVVASTFCGTPYYLAPELWNNKRYNKKAD 206 Query: 467 VYSFGVVLLELLTGRKPVDHTLPRGQQSLVTWAT----PRLSEDKVRQCVDSRLGGD 309 V+S GV+L E++ +KP + +G S V T P + ++ VD L D Sbjct: 207 VWSLGVLLYEIMGMKKPFSASNLKGLMSKVLAGTYAPLPDSFSSEFKRVVDGILVAD 263
>MOS_RAT (P00539) Proto-oncogene serine/threonine-protein kinase mos (EC| 2.7.11.1) (c-mos) (Oocyte maturation factor mos) Length = 339 Score = 57.8 bits (138), Expect = 3e-08 Identities = 27/77 (35%), Positives = 45/77 (58%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRVLGTFGYHAPEYAMTGQLSSKSD 468 D+K +N+L+ ++DV KI+DF S + D+ R + GT+ + APE + K+D Sbjct: 196 DLKPANILISEKDVCKISDFGCSQKLQDLRCRPSLHHIGGTYTHQAPELLKGEIATPKAD 255 Query: 467 VYSFGVVLLELLTGRKP 417 +YSFG+ L ++ T P Sbjct: 256 IYSFGITLWQMTTREVP 272
>PKN2_CLOPE (Q8XJL8) Probable serine/threonine protein kinase CPE1738 (EC| 2.7.11.1) Length = 685 Score = 57.4 bits (137), Expect = 4e-08 Identities = 28/83 (33%), Positives = 49/83 (59%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRVLGTFGYHAPEYAMTGQLSSKSD 468 D+K N+L+ +E V K+ DF ++ ++ D + H+ V+G+ Y +PE A ++D Sbjct: 133 DVKPQNILVTEEGVVKVTDFGIA-KSMDSSTIAHTNSVMGSAHYFSPEQAKGTYTDYRTD 191 Query: 467 VYSFGVVLLELLTGRKPVDHTLP 399 +YS G+VL E++TG P + P Sbjct: 192 LYSLGIVLYEMVTGVVPFNGDSP 214
>PKNA2_BIFLO (Q8G4G1) Probable serine/threonine-protein kinase pknA2 (EC| 2.7.11.1) Length = 757 Score = 57.4 bits (137), Expect = 4e-08 Identities = 34/84 (40%), Positives = 47/84 (55%), Gaps = 1/84 (1%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHST-RVLGTFGYHAPEYAMTGQLSSKS 471 DIK N+L+ D +I DF L+ A A L ST +LGT Y APE Q +++ Sbjct: 140 DIKPENILINDRGHVQITDFGLAKAASQ--ATLSSTGMLLGTAAYLAPEMIENNQATAQG 197 Query: 470 DVYSFGVVLLELLTGRKPVDHTLP 399 D+YS G++ E+LTG+ P D P Sbjct: 198 DLYSVGIMAWEMLTGKVPFDSDNP 221
>NRKB_TRYBB (Q03428) Putative serine/threonine-protein kinase B (EC 2.7.11.1)| Length = 431 Score = 57.4 bits (137), Expect = 4e-08 Identities = 39/117 (33%), Positives = 60/117 (51%), Gaps = 4/117 (3%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRVLGTFGYHAPEYAMTGQLSSKSD 468 DIKS+NVLL + K+ DF S+Q D + + ++ GT Y APE + + K+D Sbjct: 147 DIKSANVLLTSTGLVKLGDFGFSHQYEDTVSGVVASTFCGTPYYLAPELWNNLRYNKKAD 206 Query: 467 VYSFGVVLLELLTGRKPVDHTLPRGQQSLVTWAT----PRLSEDKVRQCVDSRLGGD 309 V+S GV+L E++ +KP + +G S V T P + ++ VD L D Sbjct: 207 VWSLGVLLYEIMGMKKPFSASNLKGLMSKVLAGTYAPLPDSFSSEFKRVVDGILVAD 263
>MOS_MSVMO (P00538) Serine/threonine-protein kinase transforming protein mos| (EC 2.7.11.1) Length = 374 Score = 56.2 bits (134), Expect = 9e-08 Identities = 28/78 (35%), Positives = 46/78 (58%), Gaps = 1/78 (1%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHS-TRVLGTFGYHAPEYAMTGQLSSKS 471 D+K +N+L+ ++DV KI+DF S + D+ R S + GT+ + APE + K+ Sbjct: 229 DLKPANILISEQDVCKISDFGCSQKLQDLRGRQASPPHIGGTYTHQAPEILKGEIATPKA 288 Query: 470 DVYSFGVVLLELLTGRKP 417 D+YSFG+ L ++ T P Sbjct: 289 DIYSFGITLWQMTTREVP 306
>MOS_MSVMH (P07331) Serine/threonine-protein kinase transforming protein mos| (EC 2.7.11.1) Length = 374 Score = 56.2 bits (134), Expect = 9e-08 Identities = 28/78 (35%), Positives = 46/78 (58%), Gaps = 1/78 (1%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHST-RVLGTFGYHAPEYAMTGQLSSKS 471 D+K +N+L+ ++DV KI+DF S + D+ R S + GT+ + APE + K+ Sbjct: 229 DLKPANILISEQDVCKISDFGCSQKLQDLRCRQASPHHIGGTYTHQAPEILKGEIATPKA 288 Query: 470 DVYSFGVVLLELLTGRKP 417 D+YSFG+ L ++ T P Sbjct: 289 DIYSFGITLWQMTTREVP 306
>PKSC_STRCO (Q9S2C0) Serine/threonine protein kinase pksC (EC 2.7.11.1)| Length = 556 Score = 56.2 bits (134), Expect = 9e-08 Identities = 30/84 (35%), Positives = 47/84 (55%), Gaps = 1/84 (1%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHST-RVLGTFGYHAPEYAMTGQLSSKS 471 DIK NV++ V K+ DF ++ + T V+GT Y +PE A+ + ++S Sbjct: 151 DIKPGNVMMTKRGVVKVMDFGIARAMQSGVTSMTQTGMVVGTPQYLSPEQALGRGVDARS 210 Query: 470 DVYSFGVVLLELLTGRKPVDHTLP 399 D+YS G++L +L+TGR P D P Sbjct: 211 DLYSVGIMLFQLVTGRLPFDADSP 234
>MOS_MSVMM (P00537) Serine/threonine-protein kinase transforming protein mos| (EC 2.7.11.1) Length = 376 Score = 56.2 bits (134), Expect = 9e-08 Identities = 28/78 (35%), Positives = 46/78 (58%), Gaps = 1/78 (1%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHST-RVLGTFGYHAPEYAMTGQLSSKS 471 D+K +N+L+ ++DV KI+DF S + D+ R S + GT+ + APE + K+ Sbjct: 229 DLKPANILISEQDVCKISDFGCSQKLQDLRCRQASPHHIGGTYTHQAPEILKGEIATPKA 288 Query: 470 DVYSFGVVLLELLTGRKP 417 D+YSFG+ L ++ T P Sbjct: 289 DIYSFGITLWQMTTREVP 306
>PKN2_COREF (Q8FUI4) Serine/threonine protein kinases drp72 (EC 2.7.11.1)| Length = 520 Score = 55.5 bits (132), Expect = 1e-07 Identities = 31/77 (40%), Positives = 45/77 (58%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRVLGTFGYHAPEYAMTGQLSSKSD 468 DIK N+L+ + KI DF ++ A + + V+GT Y +PE A Q++ SD Sbjct: 148 DIKPGNMLITANGILKITDFGIAKAAASVPLT-RTGMVVGTAQYVSPEQAQGHQVTPASD 206 Query: 467 VYSFGVVLLELLTGRKP 417 VYS GVV E+L+GR+P Sbjct: 207 VYSLGVVGYEMLSGRRP 223
>KS6A2_MOUSE (Q9WUT3) Ribosomal protein S6 kinase alpha-2 (EC 2.7.11.1)| (S6K-alpha 2) (90 kDa ribosomal protein S6 kinase 2) (p90-RSK 2) (Ribosomal S6 kinase 3) (RSK-3) (pp90RSK3) (Protein-tyrosine kinase Mpk-9) (MAP kinase-activated protein kinase 1c) (M Length = 733 Score = 55.5 bits (132), Expect = 1e-07 Identities = 32/77 (41%), Positives = 43/77 (55%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRVLGTFGYHAPEYAMTGQLSSKSD 468 D+K N+LL +E KI DF LS +A D R +S GT Y APE + +D Sbjct: 184 DLKPENILLDEEGHIKITDFGLSKEATDHDKRAYS--FCGTIEYMAPEVVNRRGHTQSAD 241 Query: 467 VYSFGVVLLELLTGRKP 417 +SFGV++ E+LTG P Sbjct: 242 WWSFGVLMFEMLTGSLP 258 Score = 32.3 bits (72), Expect = 1.3 Identities = 24/81 (29%), Positives = 36/81 (44%), Gaps = 4/81 (4%) Frame = -2 Query: 647 DIKSSNVLLFDE----DVAKIADFDLSNQAPDMAARLHSTRVLGTFGYHAPEYAMTGQLS 480 D+K SN+L DE + +I DF + Q L + T + APE Sbjct: 532 DLKPSNILYMDESGNPESIRICDFGFAKQLRAENGLLMTPCY--TANFVAPEVLKRQGYD 589 Query: 479 SKSDVYSFGVVLLELLTGRKP 417 + DV+S G++L +L G P Sbjct: 590 AACDVWSLGILLYTMLAGFTP 610
>SPKA_SYNY3 (Q9FAB3) Serine/threonine-protein kinase A (EC 2.7.11.1)| Length = 521 Score = 55.1 bits (131), Expect = 2e-07 Identities = 33/83 (39%), Positives = 49/83 (59%), Gaps = 5/83 (6%) Frame = -2 Query: 647 DIKSSNVLLFDE----DVAKIADFDLSNQAPDMAARLHSTRV-LGTFGYHAPEYAMTGQL 483 DIK SNVLL ++ ++ KI DF ++ AA T+ +GT Y +PE +L Sbjct: 148 DIKPSNVLLVEDPALGELVKILDFGIAKLV--QAAEESKTQAFMGTLAYCSPEQMEGKEL 205 Query: 482 SSKSDVYSFGVVLLELLTGRKPV 414 S+SD+YS GV++ E+LTG P+ Sbjct: 206 DSRSDIYSLGVMMYEMLTGEMPL 228
>PKN1_COREF (Q8FUI5) Probable serine/threonine protein kinase CE0033 (EC| 2.7.11.1) Length = 660 Score = 55.1 bits (131), Expect = 2e-07 Identities = 29/84 (34%), Positives = 47/84 (55%), Gaps = 1/84 (1%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTR-VLGTFGYHAPEYAMTGQLSSKS 471 D+K +N+++ + K+ DF ++ D + + T V+GT Y +PE A ++S Sbjct: 136 DVKPANIMINNTGGVKVMDFGIARALDDSTSAMTQTAAVIGTAQYLSPEQARGKPADARS 195 Query: 470 DVYSFGVVLLELLTGRKPVDHTLP 399 DVY+ G VL EL+TGR P + P Sbjct: 196 DVYAAGCVLYELVTGRPPFEGESP 219
>PKNB_MYCTU (P0A5S4) Probable serine/threonine-protein kinase pknB (EC| 2.7.11.1) Length = 626 Score = 55.1 bits (131), Expect = 2e-07 Identities = 28/78 (35%), Positives = 44/78 (56%), Gaps = 1/78 (1%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTR-VLGTFGYHAPEYAMTGQLSSKS 471 D+K +N+++ + K+ DF ++ D + T V+GT Y +PE A + ++S Sbjct: 138 DVKPANIMISATNAVKVMDFGIARAIADSGNSVTQTAAVIGTAQYLSPEQARGDSVDARS 197 Query: 470 DVYSFGVVLLELLTGRKP 417 DVYS G VL E+LTG P Sbjct: 198 DVYSLGCVLYEVLTGEPP 215
>PKNB_MYCBO (P0A5S5) Probable serine/threonine-protein kinase pknB (EC| 2.7.11.1) Length = 626 Score = 55.1 bits (131), Expect = 2e-07 Identities = 28/78 (35%), Positives = 44/78 (56%), Gaps = 1/78 (1%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTR-VLGTFGYHAPEYAMTGQLSSKS 471 D+K +N+++ + K+ DF ++ D + T V+GT Y +PE A + ++S Sbjct: 138 DVKPANIMISATNAVKVMDFGIARAIADSGNSVTQTAAVIGTAQYLSPEQARGDSVDARS 197 Query: 470 DVYSFGVVLLELLTGRKP 417 DVYS G VL E+LTG P Sbjct: 198 DVYSLGCVLYEVLTGEPP 215
>PKN2_MYXXA (P54736) Serine/threonine-protein kinase pkn2 (EC 2.7.11.1)| Length = 830 Score = 55.1 bits (131), Expect = 2e-07 Identities = 36/100 (36%), Positives = 55/100 (55%), Gaps = 5/100 (5%) Frame = -2 Query: 647 DIKSSNVLLFDE---DVAKIADFDLSNQA-PDMAARLHSTRV-LGTFGYHAPEYAMTGQL 483 D+K NV + + A++ DF ++ PD A+ + V LGT Y +PE A+ ++ Sbjct: 135 DLKPENVFISKSARGEQARLLDFGIARLVEPDAASSVSQIGVVLGTPEYLSPEQAVGAKV 194 Query: 482 SSKSDVYSFGVVLLELLTGRKPVDHTLPRGQQSLVTWATP 363 ++SD+YSFGV+ +L+GR P D LPR S A P Sbjct: 195 DTRSDLYSFGVLTYRVLSGRLPFDGPLPRNFLSQHASAAP 234
>KS6A2_HUMAN (Q15349) Ribosomal protein S6 kinase alpha-2 (EC 2.7.11.1)| (S6K-alpha 2) (90 kDa ribosomal protein S6 kinase 2) (p90-RSK 2) (Ribosomal S6 kinase 3) (RSK-3) (pp90RSK3) (MAP kinase-activated protein kinase 1c) (MAPKAPK1C) Length = 733 Score = 54.7 bits (130), Expect = 2e-07 Identities = 32/77 (41%), Positives = 43/77 (55%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRVLGTFGYHAPEYAMTGQLSSKSD 468 D+K N+LL +E KI DF LS +A D R +S GT Y APE + +D Sbjct: 184 DLKPENILLDEEGHIKITDFGLSKEAIDHDKRAYS--FCGTIEYMAPEVVNRRGHTQSAD 241 Query: 467 VYSFGVVLLELLTGRKP 417 +SFGV++ E+LTG P Sbjct: 242 WWSFGVLMFEMLTGSLP 258
>YES_XIPHE (P27447) Tyrosine-protein kinase Yes (EC 2.7.10.2) (p61-Yes)| Length = 543 Score = 54.3 bits (129), Expect = 3e-07 Identities = 40/116 (34%), Positives = 61/116 (52%), Gaps = 11/116 (9%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRVLGTFG--YHAPEYAMTGQLSSK 474 D++++N+L+ D V KIADF L+ D ++ R F + APE A+ G+ + K Sbjct: 396 DLRAANILVADNLVCKIADFGLARLIEDNE---YTARQGAKFPIKWTAPEAALYGRFTIK 452 Query: 473 SDVYSFGVVLLELLT-GRKP--------VDHTLPRGQQSLVTWATPRLSEDKVRQC 333 SDV+SFG++L EL+T GR P V + RG + P + +RQC Sbjct: 453 SDVWSFGILLTELVTKGRVPYPGMVNREVLEQVDRGYRMPCPQGCPESLHEMMRQC 508
>STE20_YEAST (Q03497) Serine/threonine-protein kinase STE20 (EC 2.7.11.1)| Length = 939 Score = 54.3 bits (129), Expect = 3e-07 Identities = 33/100 (33%), Positives = 53/100 (53%), Gaps = 1/100 (1%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRVLGTFGYHAPEYAMTGQLSSKSD 468 DIKS N+LL E K+ DF Q ++ L T ++GT + APE + K D Sbjct: 739 DIKSDNILLSMEGDIKLTDFGFCAQINEL--NLKRTTMVGTPYWMAPEVVSRKEYGPKVD 796 Query: 467 VYSFGVVLLELLTGRKP-VDHTLPRGQQSLVTWATPRLSE 351 ++S G++++E++ G P ++ T R + T TP+L E Sbjct: 797 IWSLGIMIIEMIEGEPPYLNETPLRALYLIATNGTPKLKE 836
>PKNA_MYCTU (P65726) Probable serine/threonine-protein kinase pknA (EC| 2.7.11.1) Length = 431 Score = 54.3 bits (129), Expect = 3e-07 Identities = 31/77 (40%), Positives = 44/77 (57%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRVLGTFGYHAPEYAMTGQLSSKSD 468 D+K N+L+ KI DF ++ +A D A + V+GT Y APE A+ S SD Sbjct: 141 DVKPGNILITPTGQVKITDFGIA-KAVDAAPVTQTGMVMGTAQYIAPEQALGHDASPASD 199 Query: 467 VYSFGVVLLELLTGRKP 417 VYS GVV E ++G++P Sbjct: 200 VYSLGVVGYEAVSGKRP 216
>PKNA_MYCBO (P65727) Probable serine/threonine-protein kinase pknA (EC| 2.7.11.1) Length = 431 Score = 54.3 bits (129), Expect = 3e-07 Identities = 31/77 (40%), Positives = 44/77 (57%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRVLGTFGYHAPEYAMTGQLSSKSD 468 D+K N+L+ KI DF ++ +A D A + V+GT Y APE A+ S SD Sbjct: 141 DVKPGNILITPTGQVKITDFGIA-KAVDAAPVTQTGMVMGTAQYIAPEQALGHDASPASD 199 Query: 467 VYSFGVVLLELLTGRKP 417 VYS GVV E ++G++P Sbjct: 200 VYSLGVVGYEAVSGKRP 216
>PKNX_STRCO (Q9XA16) Probable serine/threonine-protein kinase SCO3848 (EC| 2.7.11.1) Length = 673 Score = 53.9 bits (128), Expect = 4e-07 Identities = 31/78 (39%), Positives = 44/78 (56%), Gaps = 1/78 (1%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTR-VLGTFGYHAPEYAMTGQLSSKS 471 DIK +NV+L K+ DF ++ D + T V+GT Y +PE A Q+ ++S Sbjct: 138 DIKPANVMLTRNGQVKVMDFGIARAMGDSGMTMTQTAAVIGTAQYLSPEQAKGEQVDARS 197 Query: 470 DVYSFGVVLLELLTGRKP 417 D+YS G +L ELLT R P Sbjct: 198 DLYSTGCLLYELLTVRPP 215
>PKNA_MYCLE (P54743) Probable serine/threonine-protein kinase pknA (EC| 2.7.11.1) Length = 437 Score = 53.5 bits (127), Expect = 6e-07 Identities = 29/77 (37%), Positives = 45/77 (58%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRVLGTFGYHAPEYAMTGQLSSKSD 468 D+K N+L+ KI DF ++ +A D A + V+GT Y APE A+ + SD Sbjct: 141 DVKPGNILITPTGQVKITDFGIA-KAVDAAPVTQTGMVMGTAQYIAPEQALGHDATPASD 199 Query: 467 VYSFGVVLLELLTGRKP 417 VYS GV+ E+++G++P Sbjct: 200 VYSLGVIGYEVVSGKRP 216
>RAF1_XENLA (P09560) RAF proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (C-RAF) Length = 638 Score = 53.1 bits (126), Expect = 7e-07 Identities = 31/89 (34%), Positives = 45/89 (50%), Gaps = 3/89 (3%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRVLGTFGYHAPEYAM---TGQLSS 477 D+KS+N+ L + KI DF L+ + ++ G+ + APE S Sbjct: 459 DMKSNNIFLHEGLTVKIGDFGLATVKTRWSGSQQVEQLTGSILWMAPEVIRMQDNNPFSF 518 Query: 476 KSDVYSFGVVLLELLTGRKPVDHTLPRGQ 390 +SDVYS+G+VL EL+TG P H R Q Sbjct: 519 QSDVYSYGIVLYELMTGELPYSHIRDRDQ 547
>MOS_PIG (P50118) Proto-oncogene serine/threonine-protein kinase mos (EC| 2.7.11.1) (c-mos) (Oocyte maturation factor mos) Length = 345 Score = 53.1 bits (126), Expect = 7e-07 Identities = 26/77 (33%), Positives = 46/77 (59%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRVLGTFGYHAPEYAMTGQLSSKSD 468 D+K +N+L+ ++DV KI+DF S + D+ R + GT+ + APE ++ K+D Sbjct: 202 DLKPANILISEQDVCKISDFGCSERLEDLRFRPRH-HLGGTYTHRAPELLKGEPVTPKAD 260 Query: 467 VYSFGVVLLELLTGRKP 417 +YSF + L ++ T + P Sbjct: 261 IYSFAITLWQMTTRQVP 277
>M3LK7_DROME (P83104) Putative mitogen-activated protein kinase kinase kinase| 7-like (EC 2.7.11.25) Length = 393 Score = 53.1 bits (126), Expect = 7e-07 Identities = 34/81 (41%), Positives = 49/81 (60%), Gaps = 1/81 (1%) Frame = -2 Query: 647 DIKSSNVLLFDE-DVAKIADFDLSNQAPDMAARLHSTRVLGTFGYHAPEYAMTGQLSSKS 471 DIK N+LL+++ + KI DF L A DM+ + T + GT Y APE + ++K Sbjct: 133 DIKPQNMLLYNQHEDLKICDFGL---ATDMSN--NKTDMQGTLRYMAPEAIKHLKYTAKC 187 Query: 470 DVYSFGVVLLELLTGRKPVDH 408 DVYSFG++L EL+T + P H Sbjct: 188 DVYSFGIMLWELMTRQLPYSH 208
>PKN1_CORGL (Q8NU98) Probable serine/threonine protein kinase pknB (EC| 2.7.11.1) Length = 646 Score = 53.1 bits (126), Expect = 7e-07 Identities = 26/84 (30%), Positives = 47/84 (55%), Gaps = 1/84 (1%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTR-VLGTFGYHAPEYAMTGQLSSKS 471 D+K +N+++ + K+ DF ++ D + + T V+GT Y +PE A ++S Sbjct: 136 DVKPANIMITNTGGVKVMDFGIARAVNDSTSAMTQTSAVIGTAQYLSPEQARGKPADARS 195 Query: 470 DVYSFGVVLLELLTGRKPVDHTLP 399 D+Y+ G V+ EL+TG+ P + P Sbjct: 196 DIYATGCVMYELVTGKPPFEGESP 219
>PKN2_CORGL (Q8NU97) Serine/threonine protein kinases pknA (EC 2.7.11.1)| Length = 469 Score = 53.1 bits (126), Expect = 7e-07 Identities = 28/77 (36%), Positives = 45/77 (58%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRVLGTFGYHAPEYAMTGQLSSKSD 468 DIK N+L+ + KI DF ++ A + + V+GT Y +PE A ++++ SD Sbjct: 148 DIKPGNMLITANGIVKITDFGIAKAAAAVPLT-RTGMVVGTAQYVSPEQAQGKEVTAASD 206 Query: 467 VYSFGVVLLELLTGRKP 417 +YS GVV E++ GR+P Sbjct: 207 IYSLGVVGYEMMAGRRP 223
>BCK1_YEAST (Q01389) Serine/threonine-protein kinase BCK1/SLK1/SSP31 (EC| 2.7.11.1) Length = 1478 Score = 52.8 bits (125), Expect = 9e-07 Identities = 28/78 (35%), Positives = 49/78 (62%), Gaps = 1/78 (1%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRVLGTFGYHAPEYAMTGQ-LSSKS 471 D+K+ N+LL + + KI+DF +S ++ D+ + T + GT + APE T Q S+K Sbjct: 1303 DMKADNLLLDQDGICKISDFGISRKSKDIYSNSDMT-MRGTVFWMAPEMVDTKQGYSAKV 1361 Query: 470 DVYSFGVVLLELLTGRKP 417 D++S G ++LE+ G++P Sbjct: 1362 DIWSLGCIVLEMFAGKRP 1379
>MOS_MSVMT (P32593) Serine/threonine-protein kinase transforming protein mos| (EC 2.7.11.1) Length = 354 Score = 52.8 bits (125), Expect = 9e-07 Identities = 27/78 (34%), Positives = 45/78 (57%), Gaps = 1/78 (1%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHS-TRVLGTFGYHAPEYAMTGQLSSKS 471 D+K +N+L+ ++DV KI+DF S + + R S + GT+ + APE + K+ Sbjct: 209 DLKPANILISEQDVCKISDFGCSQKLQVLRGRQASPPHIGGTYTHQAPEILKGEIATPKA 268 Query: 470 DVYSFGVVLLELLTGRKP 417 D+YSFG+ L ++ T P Sbjct: 269 DIYSFGITLWQMTTREVP 286
>FYN_XIPHE (P27446) Proto-oncogene tyrosine-protein kinase FYN (EC 2.7.10.2)| (P59-FYN) Length = 536 Score = 52.8 bits (125), Expect = 9e-07 Identities = 34/80 (42%), Positives = 50/80 (62%), Gaps = 3/80 (3%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRVLGTFG--YHAPEYAMTGQLSSK 474 D++S+N+L+ D V KIADF L+ D ++ R F + APE A+ G+ + K Sbjct: 389 DLRSANILVGDNLVCKIADFGLARLIEDNE---YTARQGAKFPIKWTAPEAALYGRFTIK 445 Query: 473 SDVYSFGVVLLELLT-GRKP 417 SDV+SFG++L EL+T GR P Sbjct: 446 SDVWSFGILLTELVTKGRVP 465
>RAF1_CHICK (P05625) RAF proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (RAF-1) (C-RAF) (MIL proto-oncogene serine/threonine-protein kinase) (C-MIL) Length = 647 Score = 52.8 bits (125), Expect = 9e-07 Identities = 35/105 (33%), Positives = 53/105 (50%), Gaps = 6/105 (5%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRVLGTFGYHAPEYAM---TGQLSS 477 D+KS+N+ L + KI DF L+ + + G+ + APE + S Sbjct: 468 DMKSNNIFLHEGLTVKIGDFGLATVKSRWSGSQQVEQPTGSILWMAPEVIRMQDSNPFSF 527 Query: 476 KSDVYSFGVVLLELLTGRKPVDHTLPRGQQSLVT---WATPRLSE 351 +SDVYS+G+VL EL+TG P H R Q + +A+P LS+ Sbjct: 528 QSDVYSYGIVLYELMTGELPYSHINNRDQIIFMVGRGYASPDLSK 572
>PKNB_LACLA (Q9CEF5) Probable serine/threonine-protein kinase pknB (EC| 2.7.11.1) Length = 627 Score = 52.8 bits (125), Expect = 9e-07 Identities = 26/79 (32%), Positives = 44/79 (55%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRVLGTFGYHAPEYAMTGQLSSKSD 468 D+K NVL+ K+ DF ++ + + +T + G+ Y +PE A + +SD Sbjct: 136 DLKPQNVLVSSSGTVKVTDFGIAKALSETSLTQTNT-MFGSVHYLSPEQARGSNATVQSD 194 Query: 467 VYSFGVVLLELLTGRKPVD 411 +Y+ G++L ELLTG+ P D Sbjct: 195 IYAIGIILFELLTGQIPFD 213
>MOS_HUMAN (P00540) Proto-oncogene serine/threonine-protein kinase mos (EC| 2.7.11.1) (c-mos) (Oocyte maturation factor mos) Length = 346 Score = 52.8 bits (125), Expect = 9e-07 Identities = 26/78 (33%), Positives = 47/78 (60%), Gaps = 1/78 (1%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAA-RLHSTRVLGTFGYHAPEYAMTGQLSSKS 471 D+K +N+L+ ++DV KI+DF S + D+ + S + GT+ + APE ++ K+ Sbjct: 201 DLKPANILISEQDVCKISDFGCSEKLEDLLCFQTPSYPLGGTYTHRAPELLKGEGVTPKA 260 Query: 470 DVYSFGVVLLELLTGRKP 417 D+YSF + L ++ T + P Sbjct: 261 DIYSFAITLWQMTTKQAP 278
>STE7_YEAST (P06784) Serine/threonine-protein kinase STE7 (EC 2.7.12.2)| Length = 515 Score = 52.8 bits (125), Expect = 9e-07 Identities = 36/108 (33%), Positives = 57/108 (52%), Gaps = 6/108 (5%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRVLGTFGYHAPEYAMTGQLSSKSD 468 DIK SNVL+ + K+ DF +S + + A +GT Y +PE S K D Sbjct: 331 DIKPSNVLINSKGQIKLCDFGVSKKLINSIA----DTFVGTSTYMSPERIQGNVYSIKGD 386 Query: 467 VYSFGVVLLELLTGRKPV--DHTLPRG----QQSLVTWATPRLSEDKV 342 V+S G++++EL+TG P+ + P G Q +V +PRL +D++ Sbjct: 387 VWSLGLMIIELVTGEFPLGGHNDTPDGILDLLQRIVNEPSPRLPKDRI 434
>MOS_MOUSE (P00536) Proto-oncogene serine/threonine-protein kinase mos (EC| 2.7.11.1) (c-mos) (Oocyte maturation factor mos) Length = 390 Score = 52.8 bits (125), Expect = 9e-07 Identities = 27/78 (34%), Positives = 45/78 (57%), Gaps = 1/78 (1%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHST-RVLGTFGYHAPEYAMTGQLSSKS 471 D+K +N+L+ ++DV KI+DF S + + R S + GT+ + APE + K+ Sbjct: 245 DLKPANILISEQDVCKISDFGCSQKLQVLRCRQASPHHIGGTYTHQAPEILKGEIATPKA 304 Query: 470 DVYSFGVVLLELLTGRKP 417 D+YSFG+ L ++ T P Sbjct: 305 DIYSFGITLWQMTTREVP 322
>KS6A1_HUMAN (Q15418) Ribosomal protein S6 kinase alpha-1 (EC 2.7.11.1)| (S6K-alpha 1) (90 kDa ribosomal protein S6 kinase 1) (p90-RSK 1) (Ribosomal S6 kinase 1) (RSK-1) (pp90RSK1) (MAP kinase-activated protein kinase 1a) (MAPKAPK1A) Length = 735 Score = 52.4 bits (124), Expect = 1e-06 Identities = 30/77 (38%), Positives = 43/77 (55%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRVLGTFGYHAPEYAMTGQLSSKSD 468 D+K N+LL +E K+ DF LS +A D + +S GT Y APE S +D Sbjct: 187 DLKPENILLDEEGHIKLTDFGLSKEAIDHEKKAYS--FCGTVEYMAPEVVNRQGHSHSAD 244 Query: 467 VYSFGVVLLELLTGRKP 417 +S+GV++ E+LTG P Sbjct: 245 WWSYGVLMFEMLTGSLP 261
>IRAK3_HUMAN (Q9Y616) Interleukin-1 receptor-associated kinase 3 (EC 2.7.11.1)| (IRAK-3) (IL-1 receptor-associated kinase M) (IRAK-M) Length = 596 Score = 52.4 bits (124), Expect = 1e-06 Identities = 41/154 (26%), Positives = 69/154 (44%), Gaps = 5/154 (3%) Frame = -2 Query: 650 GDIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRVLGTFGYHA----PEYAMTGQL 483 G I S+N+LL D+ K+ DF +++ + + + + + H EY G+L Sbjct: 292 GSISSANILLDDQFQPKLTDFAMAHFRSHLEHQSCTINMTSSSSKHLWYMPEEYIRQGKL 351 Query: 482 SSKSDVYSFGVVLLELLTG-RKPVDHTLPRGQQSLVTWATPRLSEDKVRQCVDSRLGGDY 306 S K+DVYSFG+V++E+LTG R +D + L+ + D +D ++ Sbjct: 352 SIKTDVYSFGIVIMEVLTGCRVVLDDPKHIQLRDLLRELMEKRGLDSCLSFLDKKV-PPC 410 Query: 305 PPXXXXXXXXXXALCVQYEADFRPNMSIVVKALQ 204 P C A RP+M V+ L+ Sbjct: 411 PRNFSAKLFCLAGRCAATRAKLRPSMDEVLNTLE 444
>KS6AA_CHICK (P18652) Ribosomal protein S6 kinase 2 alpha (EC 2.7.11.1)| (Ribosomal protein S6 kinase II alpha) (S6KII-alpha) (P90-RSK) (MAP kinase-activated protein kinase 1) (MAPK-activated protein kinase 1) (MAPKAP kinase 1) (MAPKAPK-1) Length = 752 Score = 52.4 bits (124), Expect = 1e-06 Identities = 30/77 (38%), Positives = 43/77 (55%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRVLGTFGYHAPEYAMTGQLSSKSD 468 D+K N+LL +E K+ DF LS +A D + +S GT Y APE S +D Sbjct: 205 DLKPENILLDEEGHIKLTDFGLSKEAIDHEKKAYS--FCGTVEYMAPEVVNRQGHSHSAD 262 Query: 467 VYSFGVVLLELLTGRKP 417 +S+GV++ E+LTG P Sbjct: 263 WWSYGVLMFEMLTGSLP 279
>KS6AA_XENLA (P10665) Ribosomal protein S6 kinase 2 alpha (EC 2.7.11.1)| (Ribosomal protein S6 kinase II alpha) (S6KII-alpha) (P90-RSK) (MAP kinase-activated protein kinase 1) (MAPK-activated protein kinase 1) (MAPKAP kinase 1) (MAPKAPK-1) Length = 733 Score = 52.4 bits (124), Expect = 1e-06 Identities = 30/77 (38%), Positives = 43/77 (55%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRVLGTFGYHAPEYAMTGQLSSKSD 468 D+K N+LL +E K+ DF LS +A D + +S GT Y APE S +D Sbjct: 187 DLKPENILLDEEGHIKLTDFGLSKEAIDHEKKAYS--FCGTVEYMAPEVVNRQGHSHSAD 244 Query: 467 VYSFGVVLLELLTGRKP 417 +S+GV++ E+LTG P Sbjct: 245 WWSYGVLMFEMLTGSLP 261
>RAF1_HUMAN (P04049) RAF proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (Raf-1) (C-RAF) (cRaf) Length = 648 Score = 52.0 bits (123), Expect = 2e-06 Identities = 35/105 (33%), Positives = 52/105 (49%), Gaps = 6/105 (5%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRVLGTFGYHAPEYAM---TGQLSS 477 D+KS+N+ L + KI DF L+ + + G+ + APE S Sbjct: 468 DMKSNNIFLHEGLTVKIGDFGLATVKSRWSGSQQVEQPTGSVLWMAPEVIRMQDNNPFSF 527 Query: 476 KSDVYSFGVVLLELLTGRKPVDHTLPRGQQSLVT---WATPRLSE 351 +SDVYS+G+VL EL+TG P H R Q + +A+P LS+ Sbjct: 528 QSDVYSYGIVLYELMTGELPYSHINNRDQIIFMVGRGYASPDLSK 572
>KYK1_DICDI (P18160) Non-receptor tyrosine kinase spore lysis A (EC 2.7.10.2)| (Tyrosine-protein kinase 1) Length = 1584 Score = 51.6 bits (122), Expect = 2e-06 Identities = 37/110 (33%), Positives = 53/110 (48%), Gaps = 14/110 (12%) Frame = -2 Query: 647 DIKSSNVLLFDEDV--------------AKIADFDLSNQAPDMAARLHSTRVLGTFGYHA 510 D+ S N+LL D ++ KI+DF LS + A+++ T+ +G Y A Sbjct: 1417 DLSSRNILL-DHNIDPKNPVVSSRQDIKCKISDFGLSRLKKEQASQM--TQSVGCIPYMA 1473 Query: 509 PEYAMTGQLSSKSDVYSFGVVLLELLTGRKPVDHTLPRGQQSLVTWATPR 360 PE S KSDVYS+G+VL ELLT +P P L + + R Sbjct: 1474 PEVFKGDSNSEKSDVYSYGMVLFELLTSDEPQQDMKPMKMAHLAAYESYR 1523
>YES_CHICK (P09324) Tyrosine-protein kinase Yes (EC 2.7.10.2) (p61-Yes)| Length = 540 Score = 51.6 bits (122), Expect = 2e-06 Identities = 33/80 (41%), Positives = 50/80 (62%), Gaps = 3/80 (3%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRVLGTFG--YHAPEYAMTGQLSSK 474 D++++N+L+ D V KIADF L+ D ++ R F + APE A+ G+ + K Sbjct: 393 DLRAANILVGDNLVCKIADFGLARLIEDNE---YTARQGAKFPIKWTAPEAALYGRFTIK 449 Query: 473 SDVYSFGVVLLELLT-GRKP 417 SDV+SFG++L EL+T GR P Sbjct: 450 SDVWSFGILLTELVTKGRVP 469
>PKNF_MYCTU (P72003) Probable serine/threonine-protein kinase pknF (EC| 2.7.11.1) Length = 476 Score = 51.6 bits (122), Expect = 2e-06 Identities = 31/106 (29%), Positives = 48/106 (45%), Gaps = 4/106 (3%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAK----IADFDLSNQAPDMAARLHSTRVLGTFGYHAPEYAMTGQLS 480 D+K +N+L+ + D +ADF ++ D + + +GT Y APE M +L Sbjct: 137 DVKPANILIANPDSPDRRIMLADFGIAGWVDDPSGLTATNMTVGTVSYAAPEQLMGNELD 196 Query: 479 SKSDVYSFGVVLLELLTGRKPVDHTLPRGQQSLVTWATPRLSEDKV 342 ++D Y+ LLTG P H P S A+P D+V Sbjct: 197 GRADQYALAATAFHLLTGSPPFQHANPAVVISQHLSASPPAIGDRV 242
>PKNF_MYCBO (Q7TZN1) Probable serine/threonine-protein kinase pknF (EC| 2.7.11.1) Length = 476 Score = 51.6 bits (122), Expect = 2e-06 Identities = 31/106 (29%), Positives = 48/106 (45%), Gaps = 4/106 (3%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAK----IADFDLSNQAPDMAARLHSTRVLGTFGYHAPEYAMTGQLS 480 D+K +N+L+ + D +ADF ++ D + + +GT Y APE M +L Sbjct: 137 DVKPANILIANPDSPDRRIMLADFGIAGWVDDPSGLTATNMTVGTVSYAAPEQLMGNELD 196 Query: 479 SKSDVYSFGVVLLELLTGRKPVDHTLPRGQQSLVTWATPRLSEDKV 342 ++D Y+ LLTG P H P S A+P D+V Sbjct: 197 GRADQYALAATAFHLLTGSPPFQHANPAVVISQHLSASPPAIGDRV 242
>MST4_MOUSE (Q99JT2) Serine/threonine-protein kinase MST4 (EC 2.7.11.1)| (STE20-like kinase MST4) (MST-4) (Mammalian STE20-like protein kinase 4) Length = 416 Score = 51.6 bits (122), Expect = 2e-06 Identities = 27/77 (35%), Positives = 43/77 (55%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRVLGTFGYHAPEYAMTGQLSSKSD 468 DIK++NVLL ++ K+ADF ++ Q D ++ +GT + APE SK+D Sbjct: 144 DIKAANVLLSEQGDVKLADFGVAGQLTD--TQIKRNTFVGTPFWMAPEVIQQSAYDSKAD 201 Query: 467 VYSFGVVLLELLTGRKP 417 ++S G+ +EL G P Sbjct: 202 IWSLGITAIELAKGEPP 218
>MST4_HUMAN (Q9P289) Serine/threonine-protein kinase MST4 (EC 2.7.11.1)| (STE20-like kinase MST4) (MST-4) (Mammalian STE20-like protein kinase 4) (Serine/threonine-protein kinase MASK) (Mst3 and SOK1-related kinase) Length = 416 Score = 51.6 bits (122), Expect = 2e-06 Identities = 27/77 (35%), Positives = 43/77 (55%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRVLGTFGYHAPEYAMTGQLSSKSD 468 DIK++NVLL ++ K+ADF ++ Q D ++ +GT + APE SK+D Sbjct: 144 DIKAANVLLSEQGDVKLADFGVAGQLTD--TQIKRNTFVGTPFWMAPEVIQQSAYDSKAD 201 Query: 467 VYSFGVVLLELLTGRKP 417 ++S G+ +EL G P Sbjct: 202 IWSLGITAIELAKGEPP 218
>MATK_RAT (P41243) Megakaryocyte-associated tyrosine-protein kinase (EC| 2.7.10.2) (Tyrosine-protein kinase CTK) (Protein kinase BATK) Length = 467 Score = 51.6 bits (122), Expect = 2e-06 Identities = 49/171 (28%), Positives = 79/171 (46%), Gaps = 3/171 (1%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRVLGTFGYHAPEYAMTGQLSSKSD 468 D+ + N+L+ ++ VAK++DF L+ ++ L S+R+ + APE G+ SSKSD Sbjct: 311 DLAARNILVSEDLVAKVSDFGLAKA--ELRKGLDSSRL--PVKWTAPEALKNGRFSSKSD 366 Query: 467 VYSFGVVLLELLT-GRKPVDHTLPRGQQSLVTWATPRLSEDKVRQCVDSRLGGDYPPXXX 291 V+SFGV+L E+ + GR P P++S +V + V+ + P Sbjct: 367 VWSFGVLLWEVFSYGRAPY----------------PKMSLKEVSEAVEKGYRMEPPDSCP 410 Query: 290 XXXXXXXALCVQYEADFRPNMSIVVKALQPLLNA--RAAHPGAEHAGR*AP 144 C + E RP +V+ L L + AA G + A AP Sbjct: 411 GPVHTLMGSCWEAEPSRRPPFRKIVEKLGRELRSVGVAAPAGGQEAEGSAP 461
>YES_AVISY (P00527) Tyrosine-protein kinase transforming protein YES (EC| 2.7.10.2) (Fragment) Length = 528 Score = 51.6 bits (122), Expect = 2e-06 Identities = 33/80 (41%), Positives = 50/80 (62%), Gaps = 3/80 (3%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRVLGTFG--YHAPEYAMTGQLSSK 474 D++++N+L+ D V KIADF L+ D ++ R F + APE A+ G+ + K Sbjct: 386 DLRAANILVGDNLVCKIADFGLARLIEDNE---YTARQGAKFPIKWTAPEAALYGRFTIK 442 Query: 473 SDVYSFGVVLLELLT-GRKP 417 SDV+SFG++L EL+T GR P Sbjct: 443 SDVWSFGILLTELVTKGRVP 462
>KS6AB_XENLA (P10666) Ribosomal protein S6 kinase 2 beta (EC 2.7.11.1)| (Ribosomal protein S6 kinase II beta) (S6KII-beta) (P90-RSK) Length = 629 Score = 51.6 bits (122), Expect = 2e-06 Identities = 30/77 (38%), Positives = 43/77 (55%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRVLGTFGYHAPEYAMTGQLSSKSD 468 D+K N+LL +E K+ DF LS +A D + +S GT Y APE S +D Sbjct: 187 DLKPENILLDEEGHIKLTDFGLSKEAIDHEKKAYS--FCGTVEYMAPEVVNRQGHSHGAD 244 Query: 467 VYSFGVVLLELLTGRKP 417 +S+GV++ E+LTG P Sbjct: 245 WWSYGVLMFEMLTGSLP 261
>RAF1_RAT (P11345) RAF proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (Raf-1) (C-RAF) (cRaf) Length = 648 Score = 51.6 bits (122), Expect = 2e-06 Identities = 35/104 (33%), Positives = 51/104 (49%), Gaps = 6/104 (5%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRVLGTFGYHAPEYAM---TGQLSS 477 D+KS+N+ L + KI DF L+ + + G+ + APE S Sbjct: 468 DMKSNNIFLHEGLTVKIGDFGLATVKSRWSGSQQVEQPTGSVLWMAPEVIRMQDNNPFSF 527 Query: 476 KSDVYSFGVVLLELLTGRKPVDHTLPRGQQSLVT---WATPRLS 354 +SDVYS+G+VL EL+TG P H R Q + +A+P LS Sbjct: 528 QSDVYSYGIVLYELMTGELPYSHINNRDQIIFMVGRGYASPDLS 571
>KS6A3_MOUSE (P18654) Ribosomal protein S6 kinase alpha-3 (EC 2.7.11.1)| (S6K-alpha 3) (90 kDa ribosomal protein S6 kinase 3) (p90-RSK 3) (Ribosomal S6 kinase 2) (RSK-2) (pp90RSK2) (MAP kinase-activated protein kinase 1b) (MAPKAPK1B) Length = 740 Score = 51.6 bits (122), Expect = 2e-06 Identities = 29/77 (37%), Positives = 43/77 (55%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRVLGTFGYHAPEYAMTGQLSSKSD 468 D+K N+LL +E K+ DF LS ++ D + +S GT Y APE + +D Sbjct: 193 DLKPENILLDEEGHIKLTDFGLSKESIDHEKKAYS--FCGTVEYMAPEVVNRRGHTQSAD 250 Query: 467 VYSFGVVLLELLTGRKP 417 +SFGV++ E+LTG P Sbjct: 251 WWSFGVLMFEMLTGTLP 267 Score = 34.3 bits (77), Expect = 0.35 Identities = 25/81 (30%), Positives = 37/81 (45%), Gaps = 4/81 (4%) Frame = -2 Query: 647 DIKSSNVLLFDE----DVAKIADFDLSNQAPDMAARLHSTRVLGTFGYHAPEYAMTGQLS 480 D+K SN+L DE + +I DF + Q L + T + APE Sbjct: 539 DLKPSNILYVDESGNPESIRICDFGFAKQLRAENGLLMTPCY--TANFVAPEVLKRQGYD 596 Query: 479 SKSDVYSFGVVLLELLTGRKP 417 + D++S GV+L +LTG P Sbjct: 597 AACDIWSLGVLLYTMLTGYTP 617
>KS6A3_HUMAN (P51812) Ribosomal protein S6 kinase alpha-3 (EC 2.7.11.1)| (S6K-alpha 3) (90 kDa ribosomal protein S6 kinase 3) (p90-RSK 3) (Ribosomal S6 kinase 2) (RSK-2) (pp90RSK2) (Insulin-stimulated protein kinase 1) (ISPK-1) (MAP kinase-activated protei Length = 740 Score = 51.6 bits (122), Expect = 2e-06 Identities = 29/77 (37%), Positives = 43/77 (55%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRVLGTFGYHAPEYAMTGQLSSKSD 468 D+K N+LL +E K+ DF LS ++ D + +S GT Y APE + +D Sbjct: 193 DLKPENILLDEEGHIKLTDFGLSKESIDHEKKAYS--FCGTVEYMAPEVVNRRGHTQSAD 250 Query: 467 VYSFGVVLLELLTGRKP 417 +SFGV++ E+LTG P Sbjct: 251 WWSFGVLMFEMLTGTLP 267 Score = 34.3 bits (77), Expect = 0.35 Identities = 25/81 (30%), Positives = 37/81 (45%), Gaps = 4/81 (4%) Frame = -2 Query: 647 DIKSSNVLLFDE----DVAKIADFDLSNQAPDMAARLHSTRVLGTFGYHAPEYAMTGQLS 480 D+K SN+L DE + +I DF + Q L + T + APE Sbjct: 539 DLKPSNILYVDESGNPESIRICDFGFAKQLRAENGLLMTPCY--TANFVAPEVLKRQGYD 596 Query: 479 SKSDVYSFGVVLLELLTGRKP 417 + D++S GV+L +LTG P Sbjct: 597 AACDIWSLGVLLYTMLTGYTP 617
>MIL_AVIMH (P00531) Serine/threonine-protein kinase transforming protein mil| (EC 2.7.11.1) Length = 380 Score = 51.6 bits (122), Expect = 2e-06 Identities = 35/105 (33%), Positives = 52/105 (49%), Gaps = 6/105 (5%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRVLGTFGYHAPEYAM---TGQLSS 477 D+KS+N+ L KI DF L+ + + G+ + APE + S Sbjct: 201 DMKSNNIFLHGGLTVKIGDFGLATVKSRWSGSQQVEQPTGSILWMAPEVIRMQDSNPFSF 260 Query: 476 KSDVYSFGVVLLELLTGRKPVDHTLPRGQQSLVT---WATPRLSE 351 +SDVYS+G+VL EL+TG P H R Q + +A+P LS+ Sbjct: 261 QSDVYSYGIVLYELMTGELPYSHINNRDQIIFMVGRGYASPDLSK 305
>YRK_CHICK (Q02977) Proto-oncogene tyrosine-protein kinase Yrk (EC 2.7.10.2)| (p60-Yrk) (Yes-related kinase) Length = 535 Score = 51.6 bits (122), Expect = 2e-06 Identities = 33/80 (41%), Positives = 50/80 (62%), Gaps = 3/80 (3%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRVLGTFG--YHAPEYAMTGQLSSK 474 D++++N+L+ D V KIADF L+ D ++ R F + APE A+ G+ + K Sbjct: 388 DLRAANILVGDNLVCKIADFGLARLIEDNE---YTARQGAKFPIKWTAPEAALFGKFTIK 444 Query: 473 SDVYSFGVVLLELLT-GRKP 417 SDV+SFG++L EL+T GR P Sbjct: 445 SDVWSFGILLTELVTKGRVP 464
>STK24_HUMAN (Q9Y6E0) Serine/threonine-protein kinase 24 (EC 2.7.11.1)| (STE20-like kinase MST3) (MST-3) (Mammalian STE20-like protein kinase 3) Length = 443 Score = 51.6 bits (122), Expect = 2e-06 Identities = 42/154 (27%), Positives = 63/154 (40%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRVLGTFGYHAPEYAMTGQLSSKSD 468 DIK++NVLL + K+ADF ++ Q D ++ +GT + APE SK+D Sbjct: 156 DIKAANVLLSEHGEVKLADFGVAGQLTD--TQIKRNTFVGTPFWMAPEVIKQSAYDSKAD 213 Query: 467 VYSFGVVLLELLTGRKPVDHTLPRGQQSLVTWATPRLSEDKVRQCVDSRLGGDYPPXXXX 288 ++S G+ +EL G P P L+ P L G+Y Sbjct: 214 IWSLGITAIELARGEPPHSELHPMKVLFLIPKNNP------------PTLEGNY----SK 257 Query: 287 XXXXXXALCVQYEADFRPNMSIVVKALQPLLNAR 186 C+ E FRP ++K L NA+ Sbjct: 258 PLKEFVEACLNKEPSFRPTAKELLKHKFILRNAK 291
>M3K1_ARATH (O22040) Mitogen-activated protein kinase kinase kinase 1 (EC| 2.7.11.25) (Arabidospsis NPK1-related protein kinase 1) Length = 666 Score = 51.2 bits (121), Expect = 3e-06 Identities = 25/77 (32%), Positives = 45/77 (58%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRVLGTFGYHAPEYAMTGQLSSKSD 468 DIK +N+L+ ++ K+ADF S Q ++A + + GT + APE + S +D Sbjct: 197 DIKGANILVDNKGCIKLADFGASKQVAELATMTGAKSMKGTPYWMAPEVILQTGHSFSAD 256 Query: 467 VYSFGVVLLELLTGRKP 417 ++S G ++E++TG+ P Sbjct: 257 IWSVGCTVIEMVTGKAP 273
>PKN3_MYXXA (Q9XBQ0) Serine/threonine-protein kinase pkn3 (EC 2.7.11.1)| Length = 547 Score = 51.2 bits (121), Expect = 3e-06 Identities = 35/107 (32%), Positives = 55/107 (51%), Gaps = 7/107 (6%) Frame = -2 Query: 647 DIKSSNVLLF----DEDVAKIADFDLS---NQAPDMAARLHSTRVLGTFGYHAPEYAMTG 489 D+K N+++ + D K+ DF ++ + D A + V GT Y +PE A Sbjct: 142 DLKPENIMVEPRRNEPDFVKVLDFGIAKITDSTDDGPALTRAGFVCGTPEYMSPEQARGS 201 Query: 488 QLSSKSDVYSFGVVLLELLTGRKPVDHTLPRGQQSLVTWATPRLSED 348 QL +SD+Y+ GV+L +L+TG LP S V +AT L+E+ Sbjct: 202 QLDHRSDLYAVGVILYQLMTG------LLPFESDSAVGFATKHLTEE 242
>KS6A1_RAT (Q63531) Ribosomal protein S6 kinase alpha-1 (EC 2.7.11.1)| (S6K-alpha 1) (90 kDa ribosomal protein S6 kinase 1) (p90-RSK 1) (Ribosomal S6 kinase 1) (RSK-1) (pp90RSK1) (MAP kinase-activated protein kinase 1a) (MAPKAPK1A) Length = 735 Score = 51.2 bits (121), Expect = 3e-06 Identities = 29/77 (37%), Positives = 43/77 (55%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRVLGTFGYHAPEYAMTGQLSSKSD 468 D+K N+LL +E K+ DF LS +A D + +S GT Y APE + +D Sbjct: 187 DLKPENILLDEEGHIKLTDFGLSKEAIDHEKKAYS--FCGTVEYMAPEVVNRQGHTHSAD 244 Query: 467 VYSFGVVLLELLTGRKP 417 +S+GV++ E+LTG P Sbjct: 245 WWSYGVLMFEMLTGSLP 261
>CTR1_ARATH (Q05609) Serine/threonine-protein kinase CTR1 (EC 2.7.11.1)| Length = 821 Score = 51.2 bits (121), Expect = 3e-06 Identities = 44/158 (27%), Positives = 66/158 (41%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRVLGTFGYHAPEYAMTGQLSSKSD 468 D+KS N+L+ + K+ DF LS + L S GT + APE + KSD Sbjct: 676 DLKSPNLLVDKKYTVKVCDFGLSRLKA--STFLSSKSAAGTPEWMAPEVLRDEPSNEKSD 733 Query: 467 VYSFGVVLLELLTGRKPVDHTLPRGQQSLVTWATPRLSEDKVRQCVDSRLGGDYPPXXXX 288 VYSFGV+L EL T ++P + P + V + RL + P Sbjct: 734 VYSFGVILWELATLQQPWGNLNPAQVVAAVGFKCKRL---------------EIPRNLNP 778 Query: 287 XXXXXXALCVQYEADFRPNMSIVVKALQPLLNARAAHP 174 C E RP+ + ++ L+PL+ + P Sbjct: 779 QVAAIIEGCWTNEPWKRPSFATIMDLLRPLIKSAVPPP 816
>MOS_CERAE (P10650) Proto-oncogene serine/threonine-protein kinase mos (EC| 2.7.11.1) (c-mos) (Oocyte maturation factor mos) Length = 346 Score = 51.2 bits (121), Expect = 3e-06 Identities = 26/78 (33%), Positives = 45/78 (57%), Gaps = 1/78 (1%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRVLG-TFGYHAPEYAMTGQLSSKS 471 D+K +N+L+ ++DV KI+DF S + D+ LG T+ + APE ++ K+ Sbjct: 201 DLKPANILISEQDVCKISDFGCSEKLEDLLCFQTPLYPLGGTYTHRAPELLKGEGVTPKA 260 Query: 470 DVYSFGVVLLELLTGRKP 417 D+YSF + L ++ T + P Sbjct: 261 DIYSFAITLWQMTTKQAP 278
>PKN6_MYXXA (P54738) Serine/threonine-protein kinase pkn6 (EC 2.7.11.1)| Length = 710 Score = 51.2 bits (121), Expect = 3e-06 Identities = 28/81 (34%), Positives = 41/81 (50%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRVLGTFGYHAPEYAMTGQLSSKSD 468 D+ N+L+ + K+ DF ++ A R + V G Y PE + + D Sbjct: 143 DVSPDNILVSRQGAVKVVDFGIAKVA-GQGHRTLTGVVKGKVAYMPPEQLQAKAMDRRVD 201 Query: 467 VYSFGVVLLELLTGRKPVDHT 405 VY+ GVVL ELLTG++P D T Sbjct: 202 VYALGVVLYELLTGKRPFDAT 222
>MEK2_CAEEL (Q10664) Dual specificity mitogen-activated protein kinase kinase| mek-2 (EC 2.7.12.2) (MAP kinase kinase mek-2) Length = 387 Score = 51.2 bits (121), Expect = 3e-06 Identities = 30/78 (38%), Positives = 41/78 (52%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRVLGTFGYHAPEYAMTGQLSSKSD 468 D+K SN+L+ K+ DF +S D A +GT Y APE + SD Sbjct: 195 DVKPSNMLVNSNGEIKLCDFGVSGMLIDSMAN----SFVGTRSYMAPERLTGSHYTISSD 250 Query: 467 VYSFGVVLLELLTGRKPV 414 ++SFG+ L+ELL GR PV Sbjct: 251 IWSFGLSLVELLIGRYPV 268
>M3K9_HUMAN (P80192) Mitogen-activated protein kinase kinase kinase 9 (EC| 2.7.11.25) (Mixed lineage kinase 1) Length = 1104 Score = 50.8 bits (120), Expect = 4e-06 Identities = 33/85 (38%), Positives = 46/85 (54%), Gaps = 8/85 (9%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPD-----MAARLHSTRVL---GTFGYHAPEYAMT 492 D+KSSN+L+ K+ + DLSN+ +A H T + GT+ + APE Sbjct: 268 DLKSSNILILQ----KVENGDLSNKILKITDFGLAREWHRTTKMSAAGTYAWMAPEVIRA 323 Query: 491 GQLSSKSDVYSFGVVLLELLTGRKP 417 S SDV+S+GV+L ELLTG P Sbjct: 324 SMFSKGSDVWSYGVLLWELLTGEVP 348
>MP2K2_HUMAN (P36507) Dual specificity mitogen-activated protein kinase kinase 2| (EC 2.7.12.2) (MAP kinase kinase 2) (MAPKK 2) (ERK activator kinase 2) (MAPK/ERK kinase 2) (MEK2) Length = 400 Score = 50.8 bits (120), Expect = 4e-06 Identities = 29/78 (37%), Positives = 41/78 (52%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRVLGTFGYHAPEYAMTGQLSSKSD 468 D+K SN+L+ K+ DF +S Q D A +GT Y APE S +SD Sbjct: 194 DVKPSNILVNSRGEIKLCDFGVSGQLIDSMAN----SFVGTRSYMAPERLQGTHYSVQSD 249 Query: 467 VYSFGVVLLELLTGRKPV 414 ++S G+ L+EL GR P+ Sbjct: 250 IWSMGLSLVELAVGRYPI 267
>HIPPO_DROME (Q8T0S6) Serine/threonine-protein kinase hippo (EC 2.7.11.1)| Length = 669 Score = 50.8 bits (120), Expect = 4e-06 Identities = 29/83 (34%), Positives = 46/83 (55%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRVLGTFGYHAPEYAMTGQLSSKSD 468 DIK++N+LL E AK+ADF ++ Q D A+ ++ V+GT + APE +D Sbjct: 161 DIKAANILLNTEGYAKLADFGVAGQLTDTMAKRNT--VIGTPFWMAPEVIEEIGYDCVAD 218 Query: 467 VYSFGVVLLELLTGRKPVDHTLP 399 ++S G+ LE+ G+ P P Sbjct: 219 IWSLGITALEMAEGKPPYGEIHP 241
>TMKL1_ARATH (P33543) Putative kinase-like protein TMKL1 precursor| Length = 674 Score = 50.8 bits (120), Expect = 4e-06 Identities = 29/78 (37%), Positives = 45/78 (57%) Frame = -2 Query: 650 GDIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRVLGTFGYHAPEYAMTGQLSSKS 471 G+I+S NVL+ D A++ +F L A ++ GY APE + + +S Sbjct: 499 GNIRSKNVLVDDFFFARLTEFGLDKIMVQAVADEIVSQAKSD-GYKAPELHKMKKCNPRS 557 Query: 470 DVYSFGVVLLELLTGRKP 417 DVY+FG++LLE+L G+KP Sbjct: 558 DVYAFGILLLEILMGKKP 575
>STK24_MOUSE (Q99KH8) Serine/threonine-protein kinase 24 (EC 2.7.11.1)| Length = 431 Score = 50.8 bits (120), Expect = 4e-06 Identities = 27/77 (35%), Positives = 42/77 (54%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRVLGTFGYHAPEYAMTGQLSSKSD 468 DIK++NVLL + K+ADF ++ Q D ++ +GT + APE SK+D Sbjct: 144 DIKAANVLLSEHGEVKLADFGVAGQLTD--TQIKRNTFVGTPFWMAPEVIKQSAYDSKAD 201 Query: 467 VYSFGVVLLELLTGRKP 417 ++S G+ +EL G P Sbjct: 202 IWSLGITAIELAKGEPP 218
>BRAF1_HUMAN (P15056) B-Raf proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (p94) (v-Raf murine sarcoma viral oncogene homolog B1) Length = 766 Score = 50.4 bits (119), Expect = 5e-06 Identities = 30/89 (33%), Positives = 47/89 (52%), Gaps = 3/89 (3%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRVLGTFGYHAPEYAMT---GQLSS 477 D+KS+N+ L ++ KI DF L+ + ++ G+ + APE S Sbjct: 576 DLKSNNIFLHEDLTVKIGDFGLATVKSRWSGSHQFEQLSGSILWMAPEVIRMQDKNPYSF 635 Query: 476 KSDVYSFGVVLLELLTGRKPVDHTLPRGQ 390 +SDVY+FG+VL EL+TG+ P + R Q Sbjct: 636 QSDVYAFGIVLYELMTGQLPYSNINNRDQ 664
>BRAF1_MOUSE (P28028) B-Raf proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (Fragment) Length = 328 Score = 50.4 bits (119), Expect = 5e-06 Identities = 30/89 (33%), Positives = 47/89 (52%), Gaps = 3/89 (3%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRVLGTFGYHAPEYAMT---GQLSS 477 D+KS+N+ L ++ KI DF L+ + ++ G+ + APE S Sbjct: 138 DLKSNNIFLHEDLTVKIGDFGLATVKSRWSGSHQFEQLSGSILWMAPEVIRMQDKNPYSF 197 Query: 476 KSDVYSFGVVLLELLTGRKPVDHTLPRGQ 390 +SDVY+FG+VL EL+TG+ P + R Q Sbjct: 198 QSDVYAFGIVLYELMTGQLPYSNINNRDQ 226
>BRAF1_COTJA (P34908) B-Raf proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (RMIL serine/threonine-protein kinase) (c-RMIL) Length = 807 Score = 50.4 bits (119), Expect = 5e-06 Identities = 30/89 (33%), Positives = 47/89 (52%), Gaps = 3/89 (3%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRVLGTFGYHAPEYAMT---GQLSS 477 D+KS+N+ L ++ KI DF L+ + ++ G+ + APE S Sbjct: 616 DLKSNNIFLHEDLTVKIGDFGLATVKSRWSGSHQFEQLSGSILWMAPEVIRMQDKNPYSF 675 Query: 476 KSDVYSFGVVLLELLTGRKPVDHTLPRGQ 390 +SDVY+FG+VL EL+TG+ P + R Q Sbjct: 676 QSDVYAFGIVLYELMTGQLPYSNINNRDQ 704
>BRAF1_CHICK (Q04982) B-Raf proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (Rmil serine/threonine-protein kinase) (c-Rmil) Length = 806 Score = 50.4 bits (119), Expect = 5e-06 Identities = 30/89 (33%), Positives = 47/89 (52%), Gaps = 3/89 (3%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRVLGTFGYHAPEYAMT---GQLSS 477 D+KS+N+ L ++ KI DF L+ + ++ G+ + APE S Sbjct: 616 DLKSNNIFLHEDLTVKIGDFGLATVKSRWSGSHQFEQLSGSILWMAPEVIRMQDKNPYSF 675 Query: 476 KSDVYSFGVVLLELLTGRKPVDHTLPRGQ 390 +SDVY+FG+VL EL+TG+ P + R Q Sbjct: 676 QSDVYAFGIVLYELMTGQLPYSNINNRDQ 704
>SRK1_SPOLA (P42686) Tyrosine-protein kinase isoform SRK1 (EC 2.7.10.2)| Length = 505 Score = 50.4 bits (119), Expect = 5e-06 Identities = 30/78 (38%), Positives = 45/78 (57%), Gaps = 1/78 (1%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRVLGTFGYHAPEYAMTGQLSSKSD 468 D+ + N+L+ + + K+ADF L+ + H T + APE AM + + KSD Sbjct: 359 DLAARNILVGEHGICKVADFGLARVIDEEIYEAH-TGAKFPIKWTAPEAAMYNRFTIKSD 417 Query: 467 VYSFGVVLLELLT-GRKP 417 V+SFGVVL E++T GR P Sbjct: 418 VWSFGVVLYEIITYGRFP 435
>RMIL_AVEVR (P27966) Serine/threonine-protein kinase transforming protein Rmil| (EC 2.7.11.1) Length = 450 Score = 50.4 bits (119), Expect = 5e-06 Identities = 30/89 (33%), Positives = 47/89 (52%), Gaps = 3/89 (3%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRVLGTFGYHAPEYAMT---GQLSS 477 D+KS+N+ L ++ KI DF L+ + ++ G+ + APE S Sbjct: 202 DLKSNNIFLHEDLTVKIGDFGLATVKSRWSGSHQFEQLSGSILWMAPEVIRMQDKNPYSF 261 Query: 476 KSDVYSFGVVLLELLTGRKPVDHTLPRGQ 390 +SDVY+FG+VL EL+TG+ P + R Q Sbjct: 262 QSDVYAFGIVLYELMTGQLPYSNINNRDQ 290
>M3K2_ARATH (Q9FZ36) Mitogen-activated protein kinase kinase kinase 2 (EC| 2.7.11.25) (Arabidospsis NPK1-related protein kinase 2) Length = 651 Score = 50.4 bits (119), Expect = 5e-06 Identities = 25/77 (32%), Positives = 45/77 (58%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRVLGTFGYHAPEYAMTGQLSSKSD 468 DIK +N+L+ ++ K+ADF S Q ++A + + GT + APE + S +D Sbjct: 196 DIKGANILVDNQGCIKLADFGASKQVAELATISGAKSMKGTPYWMAPEVILQTGHSFSAD 255 Query: 467 VYSFGVVLLELLTGRKP 417 ++S G ++E++TG+ P Sbjct: 256 IWSVGCTVIEMVTGKAP 272
>M3KL4_HUMAN (Q5TCX8) Mitogen-activated protein kinase kinase kinase (EC| 2.7.11.25) (Mixed lineage kinase 4) Length = 1036 Score = 50.4 bits (119), Expect = 5e-06 Identities = 32/85 (37%), Positives = 46/85 (54%), Gaps = 8/85 (9%) Frame = -2 Query: 647 DIKSSNVLLFD----EDVA----KIADFDLSNQAPDMAARLHSTRVLGTFGYHAPEYAMT 492 D+KSSN+LL + +D+ KI DF L+ + R GT+ + APE + Sbjct: 263 DLKSSNILLLEKIEHDDICNKTLKITDFGLAREWH----RTTKMSTAGTYAWMAPEVIKS 318 Query: 491 GQLSSKSDVYSFGVVLLELLTGRKP 417 S SD++S+GV+L ELLTG P Sbjct: 319 SLFSKGSDIWSYGVLLWELLTGEVP 343
>FGFR2_DROME (Q09147) Fibroblast growth factor receptor homolog 2 precursor (EC| 2.7.10.1) (Protein breathless) (dFGF-R1) Length = 1052 Score = 50.4 bits (119), Expect = 5e-06 Identities = 41/159 (25%), Positives = 70/159 (44%), Gaps = 1/159 (0%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRVLGTFGYHAPEYAMTGQLSSKSD 468 D+ + NVL+ D V KIADF L+ D +T + APE + S+SD Sbjct: 864 DLAARNVLVSDGYVMKIADFGLARDIQDTEYYRKNTNGRLPIKWMAPESLQEKKYDSQSD 923 Query: 467 VYSFGVVLLELLT-GRKPVDHTLPRGQQSLVTWATPRLSEDKVRQCVDSRLGGDYPPXXX 291 V+S+GV+L E++T G +P H L + L ++ +K +C Sbjct: 924 VWSYGVLLWEIMTYGDQPYPHIL--SAEELYSYLITGQRMEKPAKC-------------S 968 Query: 290 XXXXXXXALCVQYEADFRPNMSIVVKALQPLLNARAAHP 174 C +E+ RP + +V++ +L +++P Sbjct: 969 LNIYVVMRQCWHFESCARPTFAELVESFDGILQQASSNP 1007
>RMIL_AVII1 (P10533) Serine/threonine-protein kinase transforming protein Rmil| (EC 2.7.11.1) Length = 367 Score = 50.4 bits (119), Expect = 5e-06 Identities = 30/89 (33%), Positives = 47/89 (52%), Gaps = 3/89 (3%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRVLGTFGYHAPEYAMT---GQLSS 477 D+KS+N+ L ++ KI DF L+ + ++ G+ + APE S Sbjct: 186 DLKSNNIFLHEDLTVKIGDFGLATVKSRWSGSHQFEQLSGSILWMAPEVIRMQDKNPYSF 245 Query: 476 KSDVYSFGVVLLELLTGRKPVDHTLPRGQ 390 +SDVY+FG+VL EL+TG+ P + R Q Sbjct: 246 QSDVYAFGIVLYELMTGQLPYSNINNRDQ 274
>HT1_ARATH (Q2MHE4) Serine/threonine-protein kinase HT1 (EC 2.7.11.1) (High| leaf temperature protein 1) Length = 390 Score = 50.4 bits (119), Expect = 5e-06 Identities = 33/86 (38%), Positives = 43/86 (50%), Gaps = 3/86 (3%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFD---LSNQAPDMAARLHSTRVLGTFGYHAPEYAMTGQLSS 477 D+KS+N+LL DE K+ADF L Q + + GT+ + APE + Sbjct: 212 DLKSNNLLLNDEMRVKVADFGTSCLETQCREAKGNM------GTYRWMAPEMIKEKPYTR 265 Query: 476 KSDVYSFGVVLLELLTGRKPVDHTLP 399 K DVYSFG+VL EL T P P Sbjct: 266 KVDVYSFGIVLWELTTALLPFQGMTP 291
>STK4_HUMAN (Q13043) Serine/threonine-protein kinase 4 (EC 2.7.11.1)| (STE20-like kinase MST1) (MST-1) (Mammalian STE20-like protein kinase 1) (Serine/threonine-protein kinase Krs-2) Length = 487 Score = 50.4 bits (119), Expect = 5e-06 Identities = 35/116 (30%), Positives = 58/116 (50%), Gaps = 10/116 (8%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRVLGTFGYHAPEYAMTGQLSSKSD 468 DIK+ N+LL E AK+ADF ++ Q D A+ ++ V+GT + APE + +D Sbjct: 149 DIKAGNILLNTEGHAKLADFGVAGQLTDTMAKRNT--VIGTPFWMAPEVIQEIGYNCVAD 206 Query: 467 VYSFGVVLLELLTGRKPVDHTLPRGQQSLV------TWATPRLSEDK----VRQCV 330 ++S G+ +E+ G+ P P ++ T+ P L D V+QC+ Sbjct: 207 IWSLGITAIEMAEGKPPYADIHPMRAIFMIPTNPPPTFRKPELWSDNFTDFVKQCL 262
>M3K10_HUMAN (Q02779) Mitogen-activated protein kinase kinase kinase 10 (EC| 2.7.11.25) (Mixed lineage kinase 2) (Protein kinase MST) Length = 954 Score = 50.1 bits (118), Expect = 6e-06 Identities = 33/88 (37%), Positives = 45/88 (51%), Gaps = 11/88 (12%) Frame = -2 Query: 647 DIKSSNVLLFD--------EDVAKIADFDLSNQAPDMAARLHSTRVL---GTFGYHAPEY 501 D+KS N+L+ + + V KI DF L+ + H T + GT+ + APE Sbjct: 222 DLKSINILILEAIENHNLADTVLKITDFGLARE-------WHKTTKMSAAGTYAWMAPEV 274 Query: 500 AMTGQLSSKSDVYSFGVVLLELLTGRKP 417 S SDV+SFGV+L ELLTG P Sbjct: 275 IRLSLFSKSSDVWSFGVLLWELLTGEVP 302
>PKND_MYCTU (O05871) Serine/threonine-protein kinase pknD (EC 2.7.11.1)| Length = 664 Score = 50.1 bits (118), Expect = 6e-06 Identities = 27/77 (35%), Positives = 41/77 (53%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRVLGTFGYHAPEYAMTGQLSSKSD 468 D+K N+L+ D A + DF ++ A D T V GT+ Y APE +++ ++D Sbjct: 138 DVKPENILVTASDFAYLVDFGIARAASDPGLTQTGTAV-GTYNYMAPERFTGDEVTYRAD 196 Query: 467 VYSFGVVLLELLTGRKP 417 +Y+ VL E LTG P Sbjct: 197 IYALACVLGECLTGAPP 213
>FES_FSVGA (P00542) Tyrosine-protein kinase transforming protein Fes (EC| 2.7.10.2) Length = 609 Score = 50.1 bits (118), Expect = 6e-06 Identities = 41/150 (27%), Positives = 63/150 (42%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRVLGTFGYHAPEYAMTGQLSSKSD 468 D+ + N L+ +++V KI+DF +S +A D + APE G+ SS+SD Sbjct: 470 DLAARNCLVTEKNVLKISDFGMSREAADGIYAASGGLRQVPVKWTAPEALNYGRYSSESD 529 Query: 467 VYSFGVVLLELLTGRKPVDHTLPRGQQSLVTWATPRLSEDKVRQCVDSRLGGDYPPXXXX 288 V+SFG++L E SL P LS + R+ V+ P Sbjct: 530 VWSFGILLWETF---------------SLGASPYPNLSNQQTREFVEKGGRLPCPELCPD 574 Query: 287 XXXXXXALCVQYEADFRPNMSIVVKALQPL 198 C YE RP+ S + + LQ + Sbjct: 575 AVFRLMEQCWAYEPGQRPSFSAIYQELQSI 604
>LRRK1_HUMAN (Q38SD2) Leucine-rich repeat serine/threonine-protein kinase 1 (EC| 2.7.11.1) Length = 2038 Score = 50.1 bits (118), Expect = 6e-06 Identities = 31/82 (37%), Positives = 47/82 (57%), Gaps = 5/82 (6%) Frame = -2 Query: 647 DIKSSNVLLFDEDVA-----KIADFDLSNQAPDMAARLHSTRVLGTFGYHAPEYAMTGQL 483 D+KS N+L++ DV K++D+ +S Q+ A V GT GY APE Sbjct: 1409 DLKSDNILVWSLDVKEHINIKLSDYGISRQSFHEGA----LGVEGTPGYQAPEIRPRIVY 1464 Query: 482 SSKSDVYSFGVVLLELLTGRKP 417 K D++S+G+VL ELL+G++P Sbjct: 1465 DEKVDMFSYGMVLYELLSGQRP 1486
>STE20_CANAL (Q92212) Serine/threonine-protein kinase STE20 homolog (EC 2.7.11.1)| Length = 1230 Score = 50.1 bits (118), Expect = 6e-06 Identities = 32/100 (32%), Positives = 53/100 (53%), Gaps = 1/100 (1%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRVLGTFGYHAPEYAMTGQLSSKSD 468 DIKS N+LL + KI DF Q ++ ++ ++GT + APE + K D Sbjct: 1073 DIKSDNILLNMDGNIKITDFGFCAQINEINSK--RITMVGTPYWMAPEIVSRKEYGPKVD 1130 Query: 467 VYSFGVVLLELLTGRKP-VDHTLPRGQQSLVTWATPRLSE 351 V+S G++++E+L G P ++ T R + T TP+L + Sbjct: 1131 VWSLGIMIIEMLEGEPPYLNETPLRALYLIATNGTPKLKD 1170
>MLTK_MOUSE (Q9ESL4) Mitogen-activated protein kinase kinase kinase MLT (EC| 2.7.11.25) (MLK-like mitogen-activated protein triple kinase) (Leucine zipper-and sterile alpha motif kinase ZAK) (Sterile alpha motif- and leucine zipper-containing kinase AZK) ( Length = 802 Score = 50.1 bits (118), Expect = 6e-06 Identities = 45/157 (28%), Positives = 68/157 (43%), Gaps = 5/157 (3%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHS----TRVLGTFGYHAPEYAMTGQLS 480 D+KS NV++ + V KI DF A+R H+ ++GTF + APE + +S Sbjct: 133 DLKSRNVVIAADGVLKICDFG--------ASRFHNHTTHMSLVGTFPWMAPEVIQSLPVS 184 Query: 479 SKSDVYSFGVVLLELLTGRKPVDHTLPRGQQSL-VTWATPRLSEDKVRQCVDSRLGGDYP 303 D YS+GVVL E+LT P +G + L V W +E RL P Sbjct: 185 ETCDTYSYGVVLWEMLTREVPF-----KGLEGLQVAWLVVEKNE---------RL--TIP 228 Query: 302 PXXXXXXXXXXALCVQYEADFRPNMSIVVKALQPLLN 192 C + +A RP+ ++ L+ + N Sbjct: 229 SSCPRSFAELLHQCWEADAKKRPSFKQIISILESMSN 265
>MLTK_HUMAN (Q9NYL2) Mitogen-activated protein kinase kinase kinase MLT (EC| 2.7.11.25) (MLK-like mitogen-activated protein triple kinase) (Leucine zipper-and sterile alpha motif-containing kinase) (Sterile alpha motif- and leucine zipper-containing kinase Length = 800 Score = 50.1 bits (118), Expect = 6e-06 Identities = 45/157 (28%), Positives = 68/157 (43%), Gaps = 5/157 (3%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHS----TRVLGTFGYHAPEYAMTGQLS 480 D+KS NV++ + V KI DF A+R H+ ++GTF + APE + +S Sbjct: 133 DLKSRNVVIAADGVLKICDFG--------ASRFHNHTTHMSLVGTFPWMAPEVIQSLPVS 184 Query: 479 SKSDVYSFGVVLLELLTGRKPVDHTLPRGQQSL-VTWATPRLSEDKVRQCVDSRLGGDYP 303 D YS+GVVL E+LT P +G + L V W +E RL P Sbjct: 185 ETCDTYSYGVVLWEMLTREVPF-----KGLEGLQVAWLVVEKNE---------RL--TIP 228 Query: 302 PXXXXXXXXXXALCVQYEADFRPNMSIVVKALQPLLN 192 C + +A RP+ ++ L+ + N Sbjct: 229 SSCPRSFAELLHQCWEADAKKRPSFKQIISILESMSN 265
>KS6A6_HUMAN (Q9UK32) Ribosomal protein S6 kinase alpha-6 (EC 2.7.11.1)| (S6K-alpha 6) (90 kDa ribosomal protein S6 kinase 6) (p90-RSK 6) (Ribosomal S6 kinase 4) (RSK-4) (pp90RSK4) Length = 745 Score = 49.7 bits (117), Expect = 8e-06 Identities = 28/77 (36%), Positives = 42/77 (54%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRVLGTFGYHAPEYAMTGQLSSKSD 468 D+K N+LL + K+ DF LS ++ D + +S GT Y APE S +D Sbjct: 198 DLKPENILLDEIGHIKLTDFGLSKESVDQEKKAYS--FCGTVEYMAPEVVNRRGHSQSAD 255 Query: 467 VYSFGVVLLELLTGRKP 417 +S+GV++ E+LTG P Sbjct: 256 WWSYGVLMFEMLTGTLP 272
>KS6A_CAEEL (Q21734) Putative ribosomal protein S6 kinase alpha (EC 2.7.11.1)| Length = 784 Score = 49.7 bits (117), Expect = 8e-06 Identities = 29/77 (37%), Positives = 41/77 (53%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRVLGTFGYHAPEYAMTGQLSSKSD 468 D+K N+LL + K+ DF LS +A D + +S GT Y APE S +D Sbjct: 229 DLKPENILLDADGHIKVTDFGLSKEAIDSEKKTYS--FCGTVEYMAPEVINRRGHSMAAD 286 Query: 467 VYSFGVVLLELLTGRKP 417 +S GV++ E+LTG P Sbjct: 287 FWSLGVLMFEMLTGHLP 303
>KIC1_YEAST (P38692) Serine/threonine-protein kinase KIC1 (EC 2.7.11.1) (Kinase| that interacts with CDC31) (N-rich kinase 1) Length = 1080 Score = 49.7 bits (117), Expect = 8e-06 Identities = 33/101 (32%), Positives = 52/101 (51%), Gaps = 2/101 (1%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRVLGTFGYHAPEYAMTG-QLSSKS 471 DIK++NVL+ +E K+ DF ++ Q + R + + GT + APE M G +K Sbjct: 144 DIKAANVLITNEGNVKLCDFGVAAQVNQTSLRRQT--MAGTPYWMAPEVIMEGVYYDTKV 201 Query: 470 DVYSFGVVLLELLTGRKP-VDHTLPRGQQSLVTWATPRLSE 351 D++S G+ E+ TG P D R Q ++ PRL + Sbjct: 202 DIWSLGITTYEIATGNPPYCDVEALRAMQLIIKSKPPRLED 242
>YES_XENLA (P10936) Tyrosine-protein kinase Yes (EC 2.7.10.2) (p61-Yes)| Length = 536 Score = 49.7 bits (117), Expect = 8e-06 Identities = 32/80 (40%), Positives = 49/80 (61%), Gaps = 3/80 (3%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRVLGTFG--YHAPEYAMTGQLSSK 474 D++++N+L+ D V KIADF L+ D ++ R F + APE A+ G+ + K Sbjct: 389 DLRAANILVGDNLVCKIADFGLARLIEDNE---YTARQGAKFPIKWTAPEAALYGRFTIK 445 Query: 473 SDVYSFGVVLLELLT-GRKP 417 SDV+SFG++L EL+ GR P Sbjct: 446 SDVWSFGILLTELVAKGRVP 465
>FYN_XENLA (P13406) Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2)| (p59-Fyn) Length = 536 Score = 49.7 bits (117), Expect = 8e-06 Identities = 32/80 (40%), Positives = 50/80 (62%), Gaps = 3/80 (3%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRVLGTFG--YHAPEYAMTGQLSSK 474 D++S+N+L+ + + KIADF L+ D ++ R F + APE A+ G+ + K Sbjct: 389 DLRSANILVGNGLICKIADFGLARLIEDNE---YTARQGAKFPIKWTAPEAALYGRFTIK 445 Query: 473 SDVYSFGVVLLELLT-GRKP 417 SDV+SFG++L EL+T GR P Sbjct: 446 SDVWSFGILLTELVTKGRVP 465
>FYN_HUMAN (P06241) Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2)| (p59-Fyn) (Protooncogene Syn) (SLK) Length = 536 Score = 49.7 bits (117), Expect = 8e-06 Identities = 32/80 (40%), Positives = 50/80 (62%), Gaps = 3/80 (3%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRVLGTFG--YHAPEYAMTGQLSSK 474 D++S+N+L+ + + KIADF L+ D ++ R F + APE A+ G+ + K Sbjct: 389 DLRSANILVGNGLICKIADFGLARLIEDNE---YTARQGAKFPIKWTAPEAALYGRFTIK 445 Query: 473 SDVYSFGVVLLELLT-GRKP 417 SDV+SFG++L EL+T GR P Sbjct: 446 SDVWSFGILLTELVTKGRVP 465
>FYN_MOUSE (P39688) Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2)| (p59-Fyn) Length = 533 Score = 49.7 bits (117), Expect = 8e-06 Identities = 32/80 (40%), Positives = 50/80 (62%), Gaps = 3/80 (3%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRVLGTFG--YHAPEYAMTGQLSSK 474 D++S+N+L+ + + KIADF L+ D ++ R F + APE A+ G+ + K Sbjct: 386 DLRSANILVGNGLICKIADFGLARLIEDNE---YTARQGAKFPIKWTAPEAALYGRFTIK 442 Query: 473 SDVYSFGVVLLELLT-GRKP 417 SDV+SFG++L EL+T GR P Sbjct: 443 SDVWSFGILLTELVTKGRVP 462
>FYN_CHICK (Q05876) Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2)| (p59-Fyn) Length = 533 Score = 49.7 bits (117), Expect = 8e-06 Identities = 32/80 (40%), Positives = 50/80 (62%), Gaps = 3/80 (3%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRVLGTFG--YHAPEYAMTGQLSSK 474 D++S+N+L+ + + KIADF L+ D ++ R F + APE A+ G+ + K Sbjct: 386 DLRSANILVGNGLICKIADFGLARLIEDNE---YTARQGAKFPIKWTAPEAALYGRFTIK 442 Query: 473 SDVYSFGVVLLELLT-GRKP 417 SDV+SFG++L EL+T GR P Sbjct: 443 SDVWSFGILLTELVTKGRVP 462
>M3K11_HUMAN (Q16584) Mitogen-activated protein kinase kinase kinase 11 (EC| 2.7.11.25) (Mixed lineage kinase 3) (Src-homology 3 domain-containing proline-rich kinase) Length = 847 Score = 49.7 bits (117), Expect = 8e-06 Identities = 33/88 (37%), Positives = 44/88 (50%), Gaps = 11/88 (12%) Frame = -2 Query: 647 DIKSSNVLLF--------DEDVAKIADFDLSNQAPDMAARLHSTRVL---GTFGYHAPEY 501 D+KS+N+LL + KI DF L+ + H T + GT+ + APE Sbjct: 241 DLKSNNILLLQPIESDDMEHKTLKITDFGLARE-------WHKTTQMSAAGTYAWMAPEV 293 Query: 500 AMTGQLSSKSDVYSFGVVLLELLTGRKP 417 S SDV+SFGV+L ELLTG P Sbjct: 294 IKASTFSKGSDVWSFGVLLWELLTGEVP 321
>MP2K2_RAT (P36506) Dual specificity mitogen-activated protein kinase kinase 2| (EC 2.7.12.2) (MAP kinase kinase 2) (MAPKK 2) (ERK activator kinase 2) (MAPK/ERK kinase 2) (MEK2) Length = 400 Score = 49.3 bits (116), Expect = 1e-05 Identities = 28/78 (35%), Positives = 41/78 (52%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRVLGTFGYHAPEYAMTGQLSSKSD 468 D+K SN+L+ K+ DF +S Q D A +GT Y +PE S +SD Sbjct: 194 DVKPSNILVNSRGEIKLCDFGVSGQLIDSMAN----SFVGTRSYMSPERLQGTHYSVQSD 249 Query: 467 VYSFGVVLLELLTGRKPV 414 ++S G+ L+EL GR P+ Sbjct: 250 IWSMGLSLVELAIGRYPI 267
>MP2K2_CYPCA (Q90321) Dual specificity mitogen-activated protein kinase kinase 2| (EC 2.7.12.2) (MAP kinase kinase 2) (MAPKK 2) (ERK activator kinase 2) (MAPK/ERK kinase 2) (MEK2) Length = 397 Score = 49.3 bits (116), Expect = 1e-05 Identities = 29/78 (37%), Positives = 41/78 (52%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRVLGTFGYHAPEYAMTGQLSSKSD 468 D+K SN+L+ K+ DF +S Q D A +GT Y +PE S +SD Sbjct: 191 DVKPSNILVNSRGEIKLCDFGVSGQLIDSMAN----SFVGTRSYMSPERLQGTHYSVQSD 246 Query: 467 VYSFGVVLLELLTGRKPV 414 V+S G+ L+EL GR P+ Sbjct: 247 VWSMGLSLVELAIGRFPI 264
>STK3_MOUSE (Q9JI10) Serine/threonine-protein kinase 3 (EC 2.7.11.1)| (STE20-like kinase MST2) (MST-2) (Mammalian STE20-like protein kinase 2) Length = 497 Score = 49.3 bits (116), Expect = 1e-05 Identities = 27/77 (35%), Positives = 45/77 (58%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRVLGTFGYHAPEYAMTGQLSSKSD 468 DIK+ N+LL E AK+ADF ++ Q D A+ ++ V+GT + APE + +D Sbjct: 146 DIKAGNILLNTEGHAKLADFGVAGQLTDTMAKRNT--VIGTPFWMAPEVIQEIGYNCVAD 203 Query: 467 VYSFGVVLLELLTGRKP 417 ++S G+ +E+ G+ P Sbjct: 204 IWSLGITSIEMAEGKPP 220
>STK3_HUMAN (Q13188) Serine/threonine-protein kinase 3 (EC 2.7.11.1)| (STE20-like kinase MST2) (MST-2) (Mammalian STE20-like protein kinase 2) (Serine/threonine-protein kinase Krs-1) Length = 491 Score = 49.3 bits (116), Expect = 1e-05 Identities = 27/77 (35%), Positives = 45/77 (58%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRVLGTFGYHAPEYAMTGQLSSKSD 468 DIK+ N+LL E AK+ADF ++ Q D A+ ++ V+GT + APE + +D Sbjct: 146 DIKAGNILLNTEGHAKLADFGVAGQLTDTMAKRNT--VIGTPFWMAPEVIQEIGYNCVAD 203 Query: 467 VYSFGVVLLELLTGRKP 417 ++S G+ +E+ G+ P Sbjct: 204 IWSLGITSIEMAEGKPP 220
>MP2K2_MOUSE (Q63932) Dual specificity mitogen-activated protein kinase kinase 2| (EC 2.7.12.2) (MAP kinase kinase 2) (MAPKK 2) (ERK activator kinase 2) (MAPK/ERK kinase 2) (MEK2) Length = 401 Score = 49.3 bits (116), Expect = 1e-05 Identities = 28/78 (35%), Positives = 41/78 (52%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRVLGTFGYHAPEYAMTGQLSSKSD 468 D+K SN+L+ K+ DF +S Q D A +GT Y +PE S +SD Sbjct: 194 DVKPSNILVNSRGEIKLCDFGVSGQLIDSMAN----SFVGTRSYMSPERLQGTHYSVQSD 249 Query: 467 VYSFGVVLLELLTGRKPV 414 ++S G+ L+EL GR P+ Sbjct: 250 IWSMGLSLVELAIGRYPI 267
>FES_FSVST (P00543) Tyrosine-protein kinase transforming protein Fes (EC| 2.7.10.2) Length = 477 Score = 49.3 bits (116), Expect = 1e-05 Identities = 41/150 (27%), Positives = 62/150 (41%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRVLGTFGYHAPEYAMTGQLSSKSD 468 D+ + N L+ +++V KI+DF +S + D L + APE G+ SS+SD Sbjct: 338 DLAARNCLVTEKNVLKISDFGMSREEADGVYAASGGLRLVPVKWTAPEALNYGRYSSESD 397 Query: 467 VYSFGVVLLELLTGRKPVDHTLPRGQQSLVTWATPRLSEDKVRQCVDSRLGGDYPPXXXX 288 V+SFG++L E SL P LS + R+ V+ P Sbjct: 398 VWSFGILLWETF---------------SLGASPYPNLSNQQTREFVEKGGRLPCPELCPD 442 Query: 287 XXXXXXALCVQYEADFRPNMSIVVKALQPL 198 C YE RP+ S + LQ + Sbjct: 443 AVFRLMEQCWAYEPGQRPSFSAFYQELQSI 472
>FES_HUMAN (P07332) Proto-oncogene tyrosine-protein kinase Fes/Fps (EC 2.7.10.2)| (C-Fes) Length = 822 Score = 49.3 bits (116), Expect = 1e-05 Identities = 44/152 (28%), Positives = 67/152 (44%), Gaps = 2/152 (1%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPD--MAARLHSTRVLGTFGYHAPEYAMTGQLSSK 474 D+ + N L+ +++V KI+DF +S + D AA S +V + APE G+ SS+ Sbjct: 683 DLAARNCLVTEKNVLKISDFGMSREEADGVYAASGGSRQV--PVKWTAPEALNYGRYSSE 740 Query: 473 SDVYSFGVVLLELLTGRKPVDHTLPRGQQSLVTWATPRLSEDKVRQCVDSRLGGDYPPXX 294 SDV+SFG++L E SL P LS + R+ V+ P Sbjct: 741 SDVWSFGILLWETF---------------SLGASPYPNLSNQQTREFVEKGGRLPCPELC 785 Query: 293 XXXXXXXXALCVQYEADFRPNMSIVVKALQPL 198 C YE RP+ S + + LQ + Sbjct: 786 PDAVFRLMEQCWAYEPGQRPSFSTIYQELQSI 817
>SRC_RSVPA (P31693) Tyrosine-protein kinase transforming protein Src (EC| 2.7.10.2) (p60-Src) (v-Src) (pp60v-src) Length = 522 Score = 48.9 bits (115), Expect = 1e-05 Identities = 31/80 (38%), Positives = 49/80 (61%), Gaps = 3/80 (3%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRVLGTFG--YHAPEYAMTGQLSSK 474 D++++N+L+ + V K+ADF L+ D ++ R F + APE A+ G+ + K Sbjct: 382 DLRAANILVGENLVCKVADFGLARLIEDNE---YTARPGARFPVKWTAPEAALYGRFTIK 438 Query: 473 SDVYSFGVVLLELLT-GRKP 417 SDV+SFG++L EL T GR P Sbjct: 439 SDVWSFGILLTELTTKGRVP 458
>SRC_RAT (Q9WUD9) Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2)| (p60-Src) (c-Src) (pp60c-src) Length = 535 Score = 48.9 bits (115), Expect = 1e-05 Identities = 31/80 (38%), Positives = 49/80 (61%), Gaps = 3/80 (3%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRVLGTFG--YHAPEYAMTGQLSSK 474 D++++N+L+ + V K+ADF L+ D ++ R F + APE A+ G+ + K Sbjct: 388 DLRAANILVGENLVCKVADFGLARLIEDNE---YTARQGAKFPIKWTAPEAALYGRFTIK 444 Query: 473 SDVYSFGVVLLELLT-GRKP 417 SDV+SFG++L EL T GR P Sbjct: 445 SDVWSFGILLTELTTKGRVP 464
>SRC_HUMAN (P12931) Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2)| (p60-Src) (c-Src) (pp60c-src) Length = 535 Score = 48.9 bits (115), Expect = 1e-05 Identities = 31/80 (38%), Positives = 49/80 (61%), Gaps = 3/80 (3%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRVLGTFG--YHAPEYAMTGQLSSK 474 D++++N+L+ + V K+ADF L+ D ++ R F + APE A+ G+ + K Sbjct: 388 DLRAANILVGENLVCKVADFGLARLIEDNE---YTARQGAKFPIKWTAPEAALYGRFTIK 444 Query: 473 SDVYSFGVVLLELLT-GRKP 417 SDV+SFG++L EL T GR P Sbjct: 445 SDVWSFGILLTELTTKGRVP 464
>PKNH_MYCTU (Q11053) Probable serine/threonine-protein kinase pknH (EC| 2.7.11.1) Length = 626 Score = 48.9 bits (115), Expect = 1e-05 Identities = 26/77 (33%), Positives = 42/77 (54%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRVLGTFGYHAPEYAMTGQLSSKSD 468 D+K N+L+ +D A + DF +++ D T V GT+ Y APE +++ ++D Sbjct: 139 DVKPQNILITRDDFAYLVDFGIASATTDEKLTQLGTAV-GTWKYMAPERFSNDEVTYRAD 197 Query: 467 VYSFGVVLLELLTGRKP 417 +Y+ VL E LTG P Sbjct: 198 IYALACVLHECLTGAPP 214
>MP2K2_CHICK (Q90891) Dual specificity mitogen-activated protein kinase kinase 2| (EC 2.7.12.2) (MAP kinase kinase 2) (MAPKK 2) (ERK activator kinase 2) (MAPK/ERK kinase 2) (MEK2) Length = 398 Score = 48.9 bits (115), Expect = 1e-05 Identities = 28/78 (35%), Positives = 41/78 (52%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRVLGTFGYHAPEYAMTGQLSSKSD 468 D+K SN+L+ K+ DF +S Q D A +GT Y +PE S +SD Sbjct: 192 DVKPSNILVNSRGEIKLCDFGVSGQLIDSMAN----SFVGTRSYMSPERLQGTHYSVQSD 247 Query: 467 VYSFGVVLLELLTGRKPV 414 ++S G+ L+EL GR P+ Sbjct: 248 IWSMGLSLVELSIGRYPI 265
>STK25_HUMAN (O00506) Serine/threonine-protein kinase 25 (EC 2.7.11.1) (Sterile| 20/oxidant stress-response kinase 1) (Ste20/oxidant stress response kinase 1) (SOK-1) (Ste20-like kinase) Length = 426 Score = 48.9 bits (115), Expect = 1e-05 Identities = 26/77 (33%), Positives = 42/77 (54%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRVLGTFGYHAPEYAMTGQLSSKSD 468 DIK++NVLL ++ K+ADF ++ Q D ++ +GT + APE K+D Sbjct: 140 DIKAANVLLSEQGDVKLADFGVAGQLTD--TQIKRNTFVGTPFWMAPEVIKQSAYDFKAD 197 Query: 467 VYSFGVVLLELLTGRKP 417 ++S G+ +EL G P Sbjct: 198 IWSLGITAIELAKGEPP 214
>MP2K1_CRIGR (Q63980) Dual specificity mitogen-activated protein kinase kinase 1| (EC 2.7.12.2) (MAP kinase kinase 1) (MAPKK 1) (ERK activator kinase 1) (MAPK/ERK kinase 1) (MEK1) Length = 393 Score = 48.9 bits (115), Expect = 1e-05 Identities = 27/78 (34%), Positives = 41/78 (52%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRVLGTFGYHAPEYAMTGQLSSKSD 468 D+K SN+L+ K+ DF +S Q D A +GT Y +PE S +SD Sbjct: 190 DVKPSNILVNSRGEIKLCDFGVSGQLIDSMAN----SFVGTRSYMSPERLQGTHYSVQSD 245 Query: 467 VYSFGVVLLELLTGRKPV 414 ++S G+ L+E+ GR P+ Sbjct: 246 IWSMGLSLVEMAVGRYPI 263
>RIPK3_HUMAN (Q9Y572) Receptor-interacting serine/threonine-protein kinase 3 (EC| 2.7.11.1) (RIP-like protein kinase 3) (Receptor-interacting protein 3) (RIP-3) Length = 518 Score = 48.9 bits (115), Expect = 1e-05 Identities = 32/78 (41%), Positives = 43/78 (55%), Gaps = 2/78 (2%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRVLGTFGYHAPEYAMT--GQLSSK 474 D+K SNVL E K+ADF LS + S GT GY APE + + S+ Sbjct: 142 DLKPSNVLPDPELHVKLADFGLSTFQGGSQSGTGSGEPGGTLGYLAPELFVNVNRKASTA 201 Query: 473 SDVYSFGVVLLELLTGRK 420 SDVYSFG+++ +L GR+ Sbjct: 202 SDVYSFGILMWAVLAGRE 219
>SRC_AVIST (P14085) Tyrosine-protein kinase transforming protein Src (EC| 2.7.10.2) (p60-Src) (v-Src) (pp60v-src) Length = 556 Score = 48.9 bits (115), Expect = 1e-05 Identities = 31/80 (38%), Positives = 49/80 (61%), Gaps = 3/80 (3%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRVLGTFG--YHAPEYAMTGQLSSK 474 D++++N+L+ + V K+ADF L+ D ++ R F + APE A+ G+ + K Sbjct: 385 DLRAANILVGENLVCKVADFGLARLIEDNE---YTARQGAKFPIKWTAPEAALYGRFTIK 441 Query: 473 SDVYSFGVVLLELLT-GRKP 417 SDV+SFG++L EL T GR P Sbjct: 442 SDVWSFGILLTELTTKGRVP 461
>SRC_RSVSE (P63185) Tyrosine-protein kinase transforming protein Src (EC| 2.7.10.2) (p60-Src) (v-Src) (pp60v-src) Length = 525 Score = 48.9 bits (115), Expect = 1e-05 Identities = 31/80 (38%), Positives = 49/80 (61%), Gaps = 3/80 (3%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRVLGTFG--YHAPEYAMTGQLSSK 474 D++++N+L+ + V K+ADF L+ D ++ R F + APE A+ G+ + K Sbjct: 385 DLRAANILVGENLVCKVADFGLARLIEDNE---YTARQGAKFPIKWTAPEAALYGRFTIK 441 Query: 473 SDVYSFGVVLLELLT-GRKP 417 SDV+SFG++L EL T GR P Sbjct: 442 SDVWSFGILLTELTTKGRVP 461
>SRC_RSVSA (P00524) Tyrosine-protein kinase transforming protein Src (EC| 2.7.10.2) (p60-Src) (v-Src) (pp60v-src) Length = 525 Score = 48.9 bits (115), Expect = 1e-05 Identities = 31/80 (38%), Positives = 49/80 (61%), Gaps = 3/80 (3%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRVLGTFG--YHAPEYAMTGQLSSK 474 D++++N+L+ + V K+ADF L+ D ++ R F + APE A+ G+ + K Sbjct: 385 DLRAANILVGENLVCKVADFGLARLIEDNE---YTARQGAKFPIKWTAPEAALYGRFTIK 441 Query: 473 SDVYSFGVVLLELLT-GRKP 417 SDV+SFG++L EL T GR P Sbjct: 442 SDVWSFGILLTELTTKGRVP 461
>SRC_RSVP (P00526) Tyrosine-protein kinase transforming protein Src (EC| 2.7.10.2) (p60-Src) (v-Src) (pp60v-src) Length = 525 Score = 48.9 bits (115), Expect = 1e-05 Identities = 31/80 (38%), Positives = 49/80 (61%), Gaps = 3/80 (3%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRVLGTFG--YHAPEYAMTGQLSSK 474 D++++N+L+ + V K+ADF L+ D ++ R F + APE A+ G+ + K Sbjct: 385 DLRAANILVGENLVCKVADFGLARLIEDNE---YTARQGAKFPIKWTAPEAALYGRFTIK 441 Query: 473 SDVYSFGVVLLELLT-GRKP 417 SDV+SFG++L EL T GR P Sbjct: 442 SDVWSFGILLTELTTKGRVP 461
>SRC_RSVH1 (P25020) Tyrosine-protein kinase transforming protein Src (EC| 2.7.10.2) (p60-Src) (v-Src) (pp60v-src) Length = 525 Score = 48.9 bits (115), Expect = 1e-05 Identities = 31/80 (38%), Positives = 49/80 (61%), Gaps = 3/80 (3%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRVLGTFG--YHAPEYAMTGQLSSK 474 D++++N+L+ + V K+ADF L+ D ++ R F + APE A+ G+ + K Sbjct: 385 DLRAANILVGENLVCKVADFGLARLIEDNE---YTARQGAKFPIKWTAPEAALYGRFTIK 441 Query: 473 SDVYSFGVVLLELLT-GRKP 417 SDV+SFG++L EL T GR P Sbjct: 442 SDVWSFGILLTELTTKGRVP 461
>SRC_AVISR (P00525) Tyrosine-protein kinase transforming protein Src (EC| 2.7.10.2) (p60-Src) (v-Src) (pp60v-src) Length = 525 Score = 48.9 bits (115), Expect = 1e-05 Identities = 31/80 (38%), Positives = 49/80 (61%), Gaps = 3/80 (3%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRVLGTFG--YHAPEYAMTGQLSSK 474 D++++N+L+ + V K+ADF L+ D ++ R F + APE A+ G+ + K Sbjct: 385 DLRAANILVGENLVCKVADFGLARLIEDNE---YTARQGAKFPIKWTAPEAALYGRFTIK 441 Query: 473 SDVYSFGVVLLELLT-GRKP 417 SDV+SFG++L EL T GR P Sbjct: 442 SDVWSFGILLTELTTKGRVP 461
>SRC_AVISS (P14084) Tyrosine-protein kinase transforming protein Src (EC| 2.7.10.2) (p60-Src) (v-Src) (pp60v-src) Length = 567 Score = 48.9 bits (115), Expect = 1e-05 Identities = 31/80 (38%), Positives = 49/80 (61%), Gaps = 3/80 (3%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRVLGTFG--YHAPEYAMTGQLSSK 474 D++++N+L+ + V K+ADF L+ D ++ R F + APE A+ G+ + K Sbjct: 385 DLRAANILVGENLVCKVADFGLARLIEDNE---YTARQGAKFPIKWTAPEAALYGRFTIK 441 Query: 473 SDVYSFGVVLLELLT-GRKP 417 SDV+SFG++L EL T GR P Sbjct: 442 SDVWSFGILLTELTTKGRVP 461
>MP2K1_RAT (Q01986) Dual specificity mitogen-activated protein kinase kinase 1| (EC 2.7.12.2) (MAP kinase kinase 1) (MAPKK 1) (ERK activator kinase 1) (MAPK/ERK kinase 1) (MEK1) Length = 392 Score = 48.9 bits (115), Expect = 1e-05 Identities = 27/78 (34%), Positives = 41/78 (52%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRVLGTFGYHAPEYAMTGQLSSKSD 468 D+K SN+L+ K+ DF +S Q D A +GT Y +PE S +SD Sbjct: 189 DVKPSNILVNSRGEIKLCDFGVSGQLIDSMAN----SFVGTRSYMSPERLQGTHYSVQSD 244 Query: 467 VYSFGVVLLELLTGRKPV 414 ++S G+ L+E+ GR P+ Sbjct: 245 IWSMGLSLVEMAVGRYPI 262
>MP2K1_RABIT (P29678) Dual specificity mitogen-activated protein kinase kinase 1| (EC 2.7.12.2) (MAP kinase kinase 1) (MAPKK 1) (ERK activator kinase 1) (MAPK/ERK kinase 1) (MEK1) Length = 392 Score = 48.9 bits (115), Expect = 1e-05 Identities = 27/78 (34%), Positives = 41/78 (52%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRVLGTFGYHAPEYAMTGQLSSKSD 468 D+K SN+L+ K+ DF +S Q D A +GT Y +PE S +SD Sbjct: 189 DVKPSNILVNSRGEIKLCDFGVSGQLIDSMAN----SFVGTRSYMSPERLQGTHYSVQSD 244 Query: 467 VYSFGVVLLELLTGRKPV 414 ++S G+ L+E+ GR P+ Sbjct: 245 IWSMGLSLVEMAVGRYPI 262
>MP2K1_MOUSE (P31938) Dual specificity mitogen-activated protein kinase kinase 1| (EC 2.7.12.2) (MAP kinase kinase 1) (MAPKK 1) (ERK activator kinase 1) (MAPK/ERK kinase 1) (MEK1) Length = 392 Score = 48.9 bits (115), Expect = 1e-05 Identities = 27/78 (34%), Positives = 41/78 (52%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRVLGTFGYHAPEYAMTGQLSSKSD 468 D+K SN+L+ K+ DF +S Q D A +GT Y +PE S +SD Sbjct: 189 DVKPSNILVNSRGEIKLCDFGVSGQLIDSMAN----SFVGTRSYMSPERLQGTHYSVQSD 244 Query: 467 VYSFGVVLLELLTGRKPV 414 ++S G+ L+E+ GR P+ Sbjct: 245 IWSMGLSLVEMAVGRYPI 262
>MP2K1_HUMAN (Q02750) Dual specificity mitogen-activated protein kinase kinase 1| (EC 2.7.12.2) (MAP kinase kinase 1) (MAPKK 1) (ERK activator kinase 1) (MAPK/ERK kinase 1) (MEK1) Length = 392 Score = 48.9 bits (115), Expect = 1e-05 Identities = 27/78 (34%), Positives = 41/78 (52%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRVLGTFGYHAPEYAMTGQLSSKSD 468 D+K SN+L+ K+ DF +S Q D A +GT Y +PE S +SD Sbjct: 189 DVKPSNILVNSRGEIKLCDFGVSGQLIDSMAN----SFVGTRSYMSPERLQGTHYSVQSD 244 Query: 467 VYSFGVVLLELLTGRKPV 414 ++S G+ L+E+ GR P+ Sbjct: 245 IWSMGLSLVEMAVGRYPI 262
>SRC2_XENLA (P13116) Tyrosine-protein kinase Src-2 (EC 2.7.10.2) (p60-Src-2)| Length = 531 Score = 48.9 bits (115), Expect = 1e-05 Identities = 31/80 (38%), Positives = 49/80 (61%), Gaps = 3/80 (3%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRVLGTFG--YHAPEYAMTGQLSSK 474 D++++N+L+ + V K+ADF L+ D ++ R F + APE A+ G+ + K Sbjct: 384 DLRAANILVGENLVCKVADFGLARLIEDNE---YTARQGAKFPIKWTAPEAALYGRFTIK 440 Query: 473 SDVYSFGVVLLELLT-GRKP 417 SDV+SFG++L EL T GR P Sbjct: 441 SDVWSFGILLTELTTKGRVP 460
>SRC1_XENLA (P13115) Tyrosine-protein kinase Src-1 (EC 2.7.10.2) (p60-Src-1)| Length = 531 Score = 48.9 bits (115), Expect = 1e-05 Identities = 31/80 (38%), Positives = 49/80 (61%), Gaps = 3/80 (3%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRVLGTFG--YHAPEYAMTGQLSSK 474 D++++N+L+ + V K+ADF L+ D ++ R F + APE A+ G+ + K Sbjct: 384 DLRAANILVGENLVCKVADFGLARLIEDNE---YTARQGAKFPIKWTAPEAALYGRFTIK 440 Query: 473 SDVYSFGVVLLELLT-GRKP 417 SDV+SFG++L EL T GR P Sbjct: 441 SDVWSFGILLTELTTKGRVP 460
>SRC_MOUSE (P05480) Neuronal proto-oncogene tyrosine-protein kinase Src (EC| 2.7.10.2) (p60-Src) (c-Src) (pp60c-src) Length = 540 Score = 48.9 bits (115), Expect = 1e-05 Identities = 31/80 (38%), Positives = 49/80 (61%), Gaps = 3/80 (3%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRVLGTFG--YHAPEYAMTGQLSSK 474 D++++N+L+ + V K+ADF L+ D ++ R F + APE A+ G+ + K Sbjct: 393 DLRAANILVGENLVCKVADFGLARLIEDNE---YTARQGAKFPIKWTAPEAALYGRFTIK 449 Query: 473 SDVYSFGVVLLELLT-GRKP 417 SDV+SFG++L EL T GR P Sbjct: 450 SDVWSFGILLTELTTKGRVP 469
>KRAF1_DROME (P11346) Raf homolog serine/threonine-protein kinase dRAF-1 (EC| 2.7.11.1) (Protein pole-hole) Length = 739 Score = 48.9 bits (115), Expect = 1e-05 Identities = 29/89 (32%), Positives = 46/89 (51%), Gaps = 3/89 (3%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRVLGTFGYHAPEYAMTGQL---SS 477 D+KS+N+ L ++ KI DF L+ + + + G+ + APE +L S Sbjct: 548 DLKSNNIFLHEDLSVKIGDFGLATAKTRWSGEKQANQPTGSILWMAPEVIRMQELNPYSF 607 Query: 476 KSDVYSFGVVLLELLTGRKPVDHTLPRGQ 390 +SDVY+FG+V+ ELL P H + Q Sbjct: 608 QSDVYAFGIVMYELLAECLPYGHISNKDQ 636
>SRC_AVIS2 (P15054) Tyrosine-protein kinase transforming protein Src (EC| 2.7.10.2) (p60-Src) (v-Src) (pp60v-src) Length = 586 Score = 48.9 bits (115), Expect = 1e-05 Identities = 31/80 (38%), Positives = 49/80 (61%), Gaps = 3/80 (3%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRVLGTFG--YHAPEYAMTGQLSSK 474 D++++N+L+ + V K+ADF L+ D ++ R F + APE A+ G+ + K Sbjct: 385 DLRAANILVGENLVCKVADFGLARLIEDNE---YTARQGAKFPIKWTAPEAALYGRFTIK 441 Query: 473 SDVYSFGVVLLELLT-GRKP 417 SDV+SFG++L EL T GR P Sbjct: 442 SDVWSFGILLTELTTKGRVP 461
>SRC_CHICK (P00523) Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2)| (p60-Src) (c-Src) (pp60c-src) Length = 532 Score = 48.9 bits (115), Expect = 1e-05 Identities = 31/80 (38%), Positives = 49/80 (61%), Gaps = 3/80 (3%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRVLGTFG--YHAPEYAMTGQLSSK 474 D++++N+L+ + V K+ADF L+ D ++ R F + APE A+ G+ + K Sbjct: 385 DLRAANILVGENLVCKVADFGLARLIEDNE---YTARQGAKFPIKWTAPEAALYGRFTIK 441 Query: 473 SDVYSFGVVLLELLT-GRKP 417 SDV+SFG++L EL T GR P Sbjct: 442 SDVWSFGILLTELTTKGRVP 461
>MP2K2_XENLA (Q07192) Dual specificity mitogen-activated protein kinase kinase 2| (EC 2.7.12.2) (MAP kinase kinase 2) (MAPKK 2) (MAPK-ERK kinase 2) (Fragment) Length = 446 Score = 48.9 bits (115), Expect = 1e-05 Identities = 34/81 (41%), Positives = 41/81 (50%), Gaps = 4/81 (4%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRVLGTFGYHAPEY----AMTGQLS 480 DIK SN+LL K+ DF +S Q D A+ TR G Y APE A Sbjct: 276 DIKPSNILLDTNGNIKLCDFGISGQLVDSIAK---TRDAGCRPYMAPERIDPSASRQGYD 332 Query: 479 SKSDVYSFGVVLLELLTGRKP 417 +SDV+S G+ L EL TGR P Sbjct: 333 VRSDVWSLGITLYELATGRFP 353
>PKNH_MYCBO (Q7U095) Probable serine/threonine-protein kinase pknH (EC| 2.7.11.1) Length = 596 Score = 48.9 bits (115), Expect = 1e-05 Identities = 26/77 (33%), Positives = 42/77 (54%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRVLGTFGYHAPEYAMTGQLSSKSD 468 D+K N+L+ +D A + DF +++ D T V GT+ Y APE +++ ++D Sbjct: 139 DVKPQNILITRDDFAYLVDFGIASATTDEKLTQLGTAV-GTWKYMAPERFSNDEVTYRAD 197 Query: 467 VYSFGVVLLELLTGRKP 417 +Y+ VL E LTG P Sbjct: 198 IYALACVLHECLTGAPP 214
>YR831_MIMIV (Q7T6Y2) Putative serine/threonine-protein kinase/receptor R831| precursor (EC 2.7.11.1) Length = 1624 Score = 48.5 bits (114), Expect = 2e-05 Identities = 29/77 (37%), Positives = 42/77 (54%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRVLGTFGYHAPEYAMTGQLSSKSD 468 DIK +N+L+ + KIADF + D GT + APE + K+D Sbjct: 1487 DIKPANILVDEHFNVKIADFGFARIKEDNTTMTRC----GTPCWTAPEVIRGEKYCEKAD 1542 Query: 467 VYSFGVVLLELLTGRKP 417 V+SFGVV+ E+LTG++P Sbjct: 1543 VFSFGVVMWEVLTGKEP 1559 Score = 47.8 bits (112), Expect = 3e-05 Identities = 29/85 (34%), Positives = 46/85 (54%), Gaps = 2/85 (2%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRVLGTFGYHAPEYA--MTGQLSSK 474 D+KS N+LL + K++DF L+ ++ + + ++GT + APE T Sbjct: 908 DLKSLNLLLDSKWNVKVSDFGLTKVKSELDKKKTNDNIIGTIHWIAPEILNDSTEVDYIL 967 Query: 473 SDVYSFGVVLLELLTGRKPVDHTLP 399 +DVYSFG++L ELLT +P P Sbjct: 968 ADVYSFGIILWELLTREQPYKGMTP 992
>YX05_CAEEL (Q11112) Putative tyrosine-protein kinase C03B1.5 in chromosome X| (EC 2.7.10.2) Length = 328 Score = 48.5 bits (114), Expect = 2e-05 Identities = 25/78 (32%), Positives = 42/78 (53%) Frame = -2 Query: 650 GDIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRVLGTFGYHAPEYAMTGQLSSKS 471 GD+ N+L+ E V K++DF ++N + + + +LGT G+ APE K+ Sbjct: 154 GDLSVKNILMTHEGVVKLSDFGMANTF-EQTRKSKNQSILGTPGFIAPEIINLQGYDGKA 212 Query: 470 DVYSFGVVLLELLTGRKP 417 D++ G++ L LL G P Sbjct: 213 DLWGLGILSLFLLKGENP 230
>FGR_FSVGR (P00544) Tyrosine-protein kinase transforming protein Fgr (EC| 2.7.10.2) Length = 545 Score = 48.5 bits (114), Expect = 2e-05 Identities = 31/80 (38%), Positives = 50/80 (62%), Gaps = 3/80 (3%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRVLGTFG--YHAPEYAMTGQLSSK 474 D++++N+L+ + V KIADF L+ D ++ R F + APE A+ G+ + K Sbjct: 405 DLRAANILVGERLVCKIADFGLARLIEDNE---YNPRQGAKFPIKWTAPEAALFGRFTIK 461 Query: 473 SDVYSFGVVLLELLT-GRKP 417 SDV+SFG++L EL++ GR P Sbjct: 462 SDVWSFGILLTELISKGRVP 481
>MP2K4_MOUSE (P47809) Dual specificity mitogen-activated protein kinase kinase 4| (EC 2.7.12.2) (MAP kinase kinase 4) (MAPKK 4) (MAPK/ERK kinase 4) (JNK-activating kinase 1) (C-JUN N-terminal kinase kinase 1) (JNK kinase 1) (JNKK 1) (SAPK/ERK kinase 1) (SE Length = 397 Score = 48.5 bits (114), Expect = 2e-05 Identities = 34/81 (41%), Positives = 41/81 (50%), Gaps = 4/81 (4%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRVLGTFGYHAPEY----AMTGQLS 480 DIK SN+LL K+ DF +S Q D A+ TR G Y APE A Sbjct: 227 DIKPSNILLDRSGNIKLCDFGISGQLVDSIAK---TRDAGCRPYMAPERIDPSASRQGYD 283 Query: 479 SKSDVYSFGVVLLELLTGRKP 417 +SDV+S G+ L EL TGR P Sbjct: 284 VRSDVWSLGITLYELATGRFP 304
>STK25_MOUSE (Q9Z2W1) Serine/threonine-protein kinase 25 (EC 2.7.11.1) (Sterile| 20/oxidant stress-response kinase 1) (Ste20/oxidant stress response kinase 1) (SOK-1) (Ste20-like kinase) Length = 426 Score = 48.5 bits (114), Expect = 2e-05 Identities = 26/77 (33%), Positives = 42/77 (54%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRVLGTFGYHAPEYAMTGQLSSKSD 468 DIK++NVLL ++ K+ADF ++ Q D ++ +GT + APE K+D Sbjct: 140 DIKAANVLLSEQGDVKMADFGVAGQLTD--TQIKRNTFVGTPFWMAPEVIKQSAYDFKAD 197 Query: 467 VYSFGVVLLELLTGRKP 417 ++S G+ +EL G P Sbjct: 198 IWSLGITAIELAKGEPP 214
>RIPK3_RAT (Q9Z2P5) Receptor-interacting serine/threonine-protein kinase 3 (EC| 2.7.11.1) (RIP-like protein kinase 3) (Receptor-interacting protein 3) (RIP-3) (Homocysteine respondent protein HCYP2) Length = 478 Score = 48.5 bits (114), Expect = 2e-05 Identities = 36/79 (45%), Positives = 45/79 (56%), Gaps = 3/79 (3%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSN-QAPDMAARLHSTRVLG-TFGYHAPEYAMT-GQLSS 477 D+K SNVLL E AK+ADF LS Q + +R G T Y APE G+ S Sbjct: 143 DLKPSNVLLDLELHAKLADFGLSTFQGGSQSGSGSGSRDSGGTLAYLAPELLDNDGKASK 202 Query: 476 KSDVYSFGVVLLELLTGRK 420 SDVYSFGV++ +L GR+ Sbjct: 203 ASDVYSFGVLVWTVLAGRE 221
>RAF_MSV36 (P00532) Serine/threonine-protein kinase transforming protein raf| (EC 2.7.11.1) Length = 323 Score = 48.5 bits (114), Expect = 2e-05 Identities = 34/104 (32%), Positives = 50/104 (48%), Gaps = 6/104 (5%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRVLGTFGYHAPEYAMT---GQLSS 477 D+KS+N+ L + KI DF L+ + + G+ + APE S Sbjct: 143 DMKSNNIFLHEGLTVKIGDFGLATVKSRWSGSQQVEQPTGSVLWMAPEVIRMQDDNPFSF 202 Query: 476 KSDVYSFGVVLLELLTGRKPVDHTLPRGQQSLVT---WATPRLS 354 +SDVYS+G+VL EL+ G P H R Q + +A+P LS Sbjct: 203 QSDVYSYGIVLYELMAGELPYAHINNRDQIIFMVGRGYASPDLS 246
>IPL1_YARLI (Q6C3J2) Spindle assembly checkpoint kinase (EC 2.7.11.1) (Aurora| kinase) Length = 371 Score = 48.5 bits (114), Expect = 2e-05 Identities = 30/88 (34%), Positives = 41/88 (46%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRVLGTFGYHAPEYAMTGQLSSKSD 468 DIK N+LL D KI+DF S AP + + GT Y PE + D Sbjct: 222 DIKPENILLHFNDTIKISDFGWSVHAPSN----RRSTLCGTMDYLPPEIVQSRPYDKNVD 277 Query: 467 VYSFGVVLLELLTGRKPVDHTLPRGQQS 384 V+S G+++ E L G P + P G Q+ Sbjct: 278 VWSLGILMYEFLCGAPPFEE--PGGAQA 303
>RAF1_MOUSE (Q99N57) RAF proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (Raf-1) (C-RAF) (cRaf) Length = 648 Score = 48.5 bits (114), Expect = 2e-05 Identities = 34/104 (32%), Positives = 50/104 (48%), Gaps = 6/104 (5%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRVLGTFGYHAPEYAMT---GQLSS 477 D+KS+N+ L + KI DF L+ + + G+ + APE S Sbjct: 468 DMKSNNIFLHEGLTVKIGDFGLATVKSRWSGSQQVEQPTGSVLWMAPEVIRMQDDNPFSF 527 Query: 476 KSDVYSFGVVLLELLTGRKPVDHTLPRGQQSLVT---WATPRLS 354 +SDVYS+G+VL EL+ G P H R Q + +A+P LS Sbjct: 528 QSDVYSYGIVLYELMAGELPYAHINNRDQIIFMVGRGYASPDLS 571
>MP2K1_SERCA (Q91447) Dual specificity mitogen-activated protein kinase kinase 1| (EC 2.7.12.2) (MAP kinase kinase 1) (MAPKK 1) (ERK activator kinase 1) (MAPK/ERK kinase 1) (MEK1) (Fragment) Length = 388 Score = 48.5 bits (114), Expect = 2e-05 Identities = 27/78 (34%), Positives = 41/78 (52%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRVLGTFGYHAPEYAMTGQLSSKSD 468 D+K SN+L+ K+ DF +S Q D A +GT Y +PE S +SD Sbjct: 183 DVKPSNILVNSRGEIKLCDFGVSGQLIDSMAN----SFVGTRSYMSPERLQGTHYSVQSD 238 Query: 467 VYSFGVVLLELLTGRKPV 414 ++S G+ L+E+ GR P+ Sbjct: 239 IWSMGLSLVEMAIGRYPI 256
>IKKB_DROME (Q9VEZ5) Inhibitor of nuclear factor kappa B kinase beta subunit| (EC 2.7.11.1) (DmIKK-beta) (Immune response deficient protein 5) (IKK-like protein) (Lipopolysaccharide-activated kinase) (DLAK) (Cactus kinase IKK) Length = 751 Score = 48.5 bits (114), Expect = 2e-05 Identities = 28/81 (34%), Positives = 43/81 (53%), Gaps = 4/81 (4%) Frame = -2 Query: 647 DIKSSNVLLF----DEDVAKIADFDLSNQAPDMAARLHSTRVLGTFGYHAPEYAMTGQLS 480 D+K N+++ + + K+ DF L+ PD V+GT Y+APE G + Sbjct: 184 DLKPDNIVIQRGVDGKKIYKLTDFGLARGTPDQTM---VQSVVGTRHYYAPEVVENGFYN 240 Query: 479 SKSDVYSFGVVLLELLTGRKP 417 S D++SFGV+ EL+TG P Sbjct: 241 STVDLWSFGVIAYELVTGELP 261
>MP2K1_XENLA (Q05116) Dual specificity mitogen-activated protein kinase kinase 1| (EC 2.7.12.2) (MAP kinase kinase 1) (MAPKK 1) (ERK activator kinase 1) (MAPK/ERK kinase 1) (MEK1) Length = 394 Score = 48.5 bits (114), Expect = 2e-05 Identities = 27/78 (34%), Positives = 41/78 (52%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRVLGTFGYHAPEYAMTGQLSSKSD 468 D+K SN+L+ K+ DF +S Q D A +GT Y +PE S +SD Sbjct: 189 DVKPSNILVNSRGEIKLCDFGVSGQLIDSMAN----SFVGTRSYMSPERLQGTHYSVQSD 244 Query: 467 VYSFGVVLLELLTGRKPV 414 ++S G+ L+E+ GR P+ Sbjct: 245 IWSMGLSLVEMAIGRYPI 262
>MP2K4_HUMAN (P45985) Dual specificity mitogen-activated protein kinase kinase 4| (EC 2.7.12.2) (MAP kinase kinase 4) (JNK-activating kinase 1) (c-Jun N-terminal kinase kinase 1) (JNKK) (SAPK/ERK kinase 1) (SEK1) Length = 399 Score = 48.5 bits (114), Expect = 2e-05 Identities = 34/81 (41%), Positives = 41/81 (50%), Gaps = 4/81 (4%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRVLGTFGYHAPEY----AMTGQLS 480 DIK SN+LL K+ DF +S Q D A+ TR G Y APE A Sbjct: 229 DIKPSNILLDRSGNIKLCDFGISGQLVDSIAK---TRDAGCRPYMAPERIDPSASRQGYD 285 Query: 479 SKSDVYSFGVVLLELLTGRKP 417 +SDV+S G+ L EL TGR P Sbjct: 286 VRSDVWSLGITLYELATGRFP 306
>PKN1_MYXXA (P33973) Serine/threonine-protein kinase pkn1 (EC 2.7.11.1)| Length = 693 Score = 48.5 bits (114), Expect = 2e-05 Identities = 25/81 (30%), Positives = 44/81 (54%), Gaps = 4/81 (4%) Frame = -2 Query: 647 DIKSSNVLLFDED----VAKIADFDLSNQAPDMAARLHSTRVLGTFGYHAPEYAMTGQLS 480 D+K N+ L + K+ DF ++ A + H+ ++GT Y APE ++ + Sbjct: 180 DLKPDNIFLVRRNGNAPFVKVLDFGIAKLADAHMPQTHAGIIVGTPEYMAPEQSLGRGVD 239 Query: 479 SKSDVYSFGVVLLELLTGRKP 417 ++D+Y+ GV+ +LLTGR P Sbjct: 240 GRADLYALGVIAYQLLTGRLP 260
>M3KSL_DROME (Q95UN8) Mitogen-activated protein kinase kinase kinase (EC| 2.7.11.25) (Mixed lineage kinase) (dMLK) (Protein slipper) Length = 1161 Score = 48.1 bits (113), Expect = 2e-05 Identities = 30/88 (34%), Positives = 48/88 (54%), Gaps = 11/88 (12%) Frame = -2 Query: 647 DIKSSNVLLFD--------EDVAKIADFDLSNQAPDMAARLHSTRVL---GTFGYHAPEY 501 D+KSSNVL+++ + KI DF L+ + +++T+ + GT+ + PE Sbjct: 264 DLKSSNVLIYEAIEGNHLQQKTLKITDFGLARE-------MYNTQRMSAAGTYAWMPPEV 316 Query: 500 AMTGQLSSKSDVYSFGVVLLELLTGRKP 417 S SDV+S+GV+L EL+TG P Sbjct: 317 ISVSTYSKFSDVWSYGVLLWELITGETP 344
>M3K4_HUMAN (Q9Y6R4) Mitogen-activated protein kinase kinase kinase 4 (EC| 2.7.11.25) (MAPK/ERK kinase kinase 4) (MEK kinase 4) (MEKK 4) (MAP three kinase 1) Length = 1607 Score = 48.1 bits (113), Expect = 2e-05 Identities = 29/84 (34%), Positives = 45/84 (53%), Gaps = 7/84 (8%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADF----DLSNQAPDMAARLHSTRVLGTFGYHAPEYAMTGQ-- 486 DIK +N+ L + K+ DF L N A M ++ST LGT Y APE + Sbjct: 1462 DIKGANIFLTSSGLIKLGDFGCSVKLKNNAQTMPGEVNST--LGTAAYMAPEVITRAKGE 1519 Query: 485 -LSSKSDVYSFGVVLLELLTGRKP 417 +D++S G V++E++TG++P Sbjct: 1520 GHGRAADIWSLGCVVIEMVTGKRP 1543
>MKH1_SCHPO (Q10407) MAP kinase kinase kinase mkh1 (EC 2.7.11.25)| Length = 1116 Score = 48.1 bits (113), Expect = 2e-05 Identities = 27/79 (34%), Positives = 46/79 (58%), Gaps = 2/79 (2%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRVLGTFGYHAPEYAMTGQ--LSSK 474 D+K+ N+L+ + V KI+DF +S + ++ + + G+ + APE S+K Sbjct: 955 DLKADNLLIDFDGVCKISDFGISKHSDNVYDNDANLSMQGSIFWMAPEVIHNDHQGYSAK 1014 Query: 473 SDVYSFGVVLLELLTGRKP 417 DV+S G V+LE+L GR+P Sbjct: 1015 VDVWSLGCVVLEMLAGRRP 1033
>FGR_MOUSE (P14234) Proto-oncogene tyrosine-protein kinase FGR (EC 2.7.10.2)| (P55-FGR) (C-FGR) Length = 517 Score = 48.1 bits (113), Expect = 2e-05 Identities = 29/78 (37%), Positives = 46/78 (58%), Gaps = 1/78 (1%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRVLGTFGYHAPEYAMTGQLSSKSD 468 D++++N+L+ + + KIADF L+ D + APE A+ G+ + KSD Sbjct: 370 DLRAANILVGEYLICKIADFGLARLIEDNEYNPQQGTKF-PIKWTAPEAALFGRFTVKSD 428 Query: 467 VYSFGVVLLELLT-GRKP 417 V+SFG++L EL+T GR P Sbjct: 429 VWSFGILLTELITKGRVP 446
>MP2K5_RAT (Q62862) Dual specificity mitogen-activated protein kinase kinase 5| (EC 2.7.12.2) (MAP kinase kinase 5) (MAPKK 5) (MAPK/ERK kinase 5) Length = 448 Score = 48.1 bits (113), Expect = 2e-05 Identities = 31/90 (34%), Positives = 46/90 (51%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRVLGTFGYHAPEYAMTGQLSSKSD 468 D+K SN+L+ K+ DF +S Q + A+ + +GT Y APE Q SD Sbjct: 283 DVKPSNMLVNTSGQVKLCDFGVSTQLVNSIAKTY----VGTNAYMAPERISGEQYGIHSD 338 Query: 467 VYSFGVVLLELLTGRKPVDHTLPRGQQSLV 378 V+S G+ +EL GR P + + Q SL+ Sbjct: 339 VWSLGISFMELALGRFPYPQ-IQKNQGSLM 367
>MATK_MOUSE (P41242) Megakaryocyte-associated tyrosine-protein kinase (EC| 2.7.10.2) (Tyrosine-protein kinase CTK) (Protein kinase NTK) Length = 505 Score = 48.1 bits (113), Expect = 2e-05 Identities = 42/148 (28%), Positives = 68/148 (45%), Gaps = 1/148 (0%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRVLGTFGYHAPEYAMTGQLSSKSD 468 D+ + N+L+ ++ VAK++DF L+ L S+R+ + APE G+ SSKSD Sbjct: 350 DLAARNILVSEDLVAKVSDFGLAKAE---RKGLDSSRL--PVKWTAPEALKNGRFSSKSD 404 Query: 467 VYSFGVVLLELLT-GRKPVDHTLPRGQQSLVTWATPRLSEDKVRQCVDSRLGGDYPPXXX 291 V+SFGV+L E+ + GR P P++S +V + V+ + P Sbjct: 405 VWSFGVLLWEVFSYGRAPY----------------PKMSLKEVSEAVEKGYRMEPPDGCP 448 Query: 290 XXXXXXXALCVQYEADFRPNMSIVVKAL 207 C + E RP +V+ L Sbjct: 449 GSVHTLMGSCWEAEPARRPPFRKIVEKL 476
>CLA4_ASHGO (Q9HFW2) Serine/threonine-protein kinase CLA4 (EC 2.7.11.1)| Length = 793 Score = 48.1 bits (113), Expect = 2e-05 Identities = 32/103 (31%), Positives = 50/103 (48%), Gaps = 1/103 (0%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRVLGTFGYHAPEYAMTGQLSSKSD 468 DIKS NVLL KI DF + D ++ ++GT + APE + K D Sbjct: 644 DIKSDNVLLDTHGRVKITDFGFCAKLTDKRSK--RATMVGTPYWMAPEVVKQREYDEKVD 701 Query: 467 VYSFGVVLLELLTGRKPVDHTLP-RGQQSLVTWATPRLSEDKV 342 V+S G++ +E+L G P + P + + T TP+L ++ Sbjct: 702 VWSLGIMTIEMLEGEPPYLNEEPLKALYLIATNGTPKLKHPEL 744
>MKK1_YEAST (P32490) MAP kinase kinase MKK1/SSP32 (EC 2.7.12.2)| Length = 508 Score = 48.1 bits (113), Expect = 2e-05 Identities = 29/77 (37%), Positives = 40/77 (51%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRVLGTFGYHAPEYAMTGQLSSKSD 468 DIK N+LL + K+ DF +S +A + A T GT Y APE S SD Sbjct: 349 DIKPQNILLNENGQVKLCDFGVSGEAVNSLA----TTFTGTSFYMAPERIQGQPYSVTSD 404 Query: 467 VYSFGVVLLELLTGRKP 417 V+S G+ +LE+ G+ P Sbjct: 405 VWSLGLTILEVANGKFP 421
>FES_MOUSE (P16879) Proto-oncogene tyrosine-protein kinase Fes/Fps (EC 2.7.10.2)| (C-Fes) Length = 820 Score = 48.1 bits (113), Expect = 2e-05 Identities = 40/150 (26%), Positives = 63/150 (42%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRVLGTFGYHAPEYAMTGQLSSKSD 468 D+ + N L+ +++V KI+DF +S + D S + APE G+ SS+SD Sbjct: 681 DLAARNCLVTEKNVLKISDFGMSREEADGIYAACSGLRQVPVKWTAPEALNYGRYSSESD 740 Query: 467 VYSFGVVLLELLTGRKPVDHTLPRGQQSLVTWATPRLSEDKVRQCVDSRLGGDYPPXXXX 288 V+SFG++L E SL P L+ + R+ V+ P Sbjct: 741 VWSFGILLWETF---------------SLGASPYPNLTNQQTREFVEKGHRLPCPELCPD 785 Query: 287 XXXXXXALCVQYEADFRPNMSIVVKALQPL 198 C YE RP+ SI+ + L + Sbjct: 786 AVFRLMEQCWAYEPGQRPSFSIICQELHSI 815
>FES_FELCA (P14238) Proto-oncogene tyrosine-protein kinase FES/FPS (EC 2.7.10.2)| (C-FES) Length = 820 Score = 48.1 bits (113), Expect = 2e-05 Identities = 40/150 (26%), Positives = 62/150 (41%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRVLGTFGYHAPEYAMTGQLSSKSD 468 D+ + N L+ +++V KI+DF +S + D + APE G+ SS+SD Sbjct: 681 DLAARNCLVTEKNVLKISDFGMSREEADGIYAASGGLRQVPVKWTAPEALNYGRYSSESD 740 Query: 467 VYSFGVVLLELLTGRKPVDHTLPRGQQSLVTWATPRLSEDKVRQCVDSRLGGDYPPXXXX 288 V+SFG++L E SL P LS + R+ V+ P Sbjct: 741 VWSFGILLWETF---------------SLGASPYPNLSNQQTREFVEKGGRLPCPELCPD 785 Query: 287 XXXXXXALCVQYEADFRPNMSIVVKALQPL 198 C YE RP+ S + + LQ + Sbjct: 786 AVFRLMEQCWAYEPGQRPSFSAIYQELQSI 815
>M3K4_MOUSE (O08648) Mitogen-activated protein kinase kinase kinase 4 (EC| 2.7.11.25) (MAPK/ERK kinase kinase 4) (MEK kinase 4) (MEKK 4) Length = 1597 Score = 48.1 bits (113), Expect = 2e-05 Identities = 29/84 (34%), Positives = 45/84 (53%), Gaps = 7/84 (8%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADF----DLSNQAPDMAARLHSTRVLGTFGYHAPEYAMTGQ-- 486 DIK +N+ L + K+ DF L N A M ++ST LGT Y APE + Sbjct: 1452 DIKGANIFLTSSGLIKLGDFGCSVKLKNNAQTMPGEVNST--LGTAAYMAPEVITRAKGE 1509 Query: 485 -LSSKSDVYSFGVVLLELLTGRKP 417 +D++S G V++E++TG++P Sbjct: 1510 GHGRAADIWSLGCVVIEMVTGKRP 1533
>FGFR1_DROME (Q07407) Fibroblast growth factor receptor homolog 1 precursor (EC| 2.7.10.1) (Protein heartless) Length = 729 Score = 47.8 bits (112), Expect = 3e-05 Identities = 40/155 (25%), Positives = 66/155 (42%), Gaps = 1/155 (0%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRVLGTFGYHAPEYAMTGQLSSKSD 468 D+ + NVL+ D+ V KIADF L+ +T + APE SKSD Sbjct: 556 DLAARNVLVSDDYVLKIADFGLARDIQSTDYYRKNTNGRLPIKWMAPESLQEKFYDSKSD 615 Query: 467 VYSFGVVLLELLT-GRKPVDHTLPRGQQSLVTWATPRLSEDKVRQCVDSRLGGDYPPXXX 291 V+S+G++L E++T G++P + + L T+ +K +C Sbjct: 616 VWSYGILLWEIMTYGQQPYPTIM--SAEELYTYLMSGQRMEKPAKC-------------S 660 Query: 290 XXXXXXXALCVQYEADFRPNMSIVVKALQPLLNAR 186 C + AD RP + +V+ + LL + Sbjct: 661 MNIYILMRQCWHFNADDRPPFTEIVEYMDKLLQTK 695
>TESK2_HUMAN (Q96S53) Dual specificity testis-specific protein kinase 2 (EC| 2.7.12.1) (Testicular protein kinase 2) Length = 571 Score = 47.8 bits (112), Expect = 3e-05 Identities = 39/155 (25%), Positives = 68/155 (43%), Gaps = 3/155 (1%) Frame = -2 Query: 647 DIKSSNVLLFDED---VAKIADFDLSNQAPDMAARLHSTRVLGTFGYHAPEYAMTGQLSS 477 D+ S N L+ ++ A +ADF L+ + PD++ V+G+ + APE + Sbjct: 176 DLTSKNCLIKRDENGYSAVVADFGLAEKIPDVSMGSEKLAVVGSPFWMAPEVLRDEPYNE 235 Query: 476 KSDVYSFGVVLLELLTGRKPVDHTLPRGQQSLVTWATPRLSEDKVRQCVDSRLGGDYPPX 297 K+DV+S+G++L E++ + LPR + L D + V GD PP Sbjct: 236 KADVFSYGIILCEIIARIQADPDYLPRTENF-------GLDYDAFQHMV-----GDCPPD 283 Query: 296 XXXXXXXXXALCVQYEADFRPNMSIVVKALQPLLN 192 C + RP+ + K L+ +L+ Sbjct: 284 FLQLTFN----CCNMDPKLRPSFVEIGKTLEEILS 314
>KPC2_DROME (P13677) Protein kinase C, eye isozyme (EC 2.7.11.13) (PKC)| (dPKC53E(EY)) (Protein INAC) (Inactivation no after-potential C protein) (Photoreceptor-specific PKC) (Eye-PKC) Length = 700 Score = 47.8 bits (112), Expect = 3e-05 Identities = 28/79 (35%), Positives = 40/79 (50%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRVLGTFGYHAPEYAMTGQLSSKSD 468 D+K N+LL E K+ DF LS + + R + GT Y APE S +D Sbjct: 495 DLKLDNILLDGEGHVKLVDFGLSKEG--VTERQTTRTFCGTPNYMAPEIVSYDPYSIAAD 552 Query: 467 VYSFGVVLLELLTGRKPVD 411 +SFGV+L E + G+ P + Sbjct: 553 WWSFGVLLFEFMAGQAPFE 571
>SHK1_SCHPO (P50527) Serine/threonine-protein kinase pak1/shk1 (EC 2.7.11.1)| Length = 658 Score = 47.8 bits (112), Expect = 3e-05 Identities = 32/107 (29%), Positives = 52/107 (48%), Gaps = 1/107 (0%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRVLGTFGYHAPEYAMTGQLSSKSD 468 DIKS N+LL + K+ DF Q + T ++GT + APE + K D Sbjct: 505 DIKSDNILLSLQGDIKLTDFGFCAQIDSNMTK--RTTMVGTPYWMAPEVVTRKEYGFKVD 562 Query: 467 VYSFGVVLLELLTGRKPVDHTLP-RGQQSLVTWATPRLSEDKVRQCV 330 V+S G++ +E++ G P + P R + T TP++S ++ V Sbjct: 563 VWSLGIMAIEMVEGEPPYLNENPLRALYLIATIGTPKISRPELLSSV 609
>YES_HUMAN (P07947) Proto-oncogene tyrosine-protein kinase Yes (EC 2.7.10.2)| (p61-Yes) (c-Yes) Length = 542 Score = 47.8 bits (112), Expect = 3e-05 Identities = 31/80 (38%), Positives = 49/80 (61%), Gaps = 3/80 (3%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRVLGTFG--YHAPEYAMTGQLSSK 474 D++++N+L+ + V KIADF L+ D ++ R F + APE A+ G+ + K Sbjct: 395 DLRAANILVGENLVCKIADFGLARLIEDNE---YTARQGAKFPIKWTAPEAALYGRFTIK 451 Query: 473 SDVYSFGVVLLELLT-GRKP 417 SDV+SFG++ EL+T GR P Sbjct: 452 SDVWSFGILQTELVTKGRVP 471
>SRC42_DROME (Q9V9J3) Tyrosine-protein kinase Src42A (EC 2.7.10.2) (Dsrc41)| Length = 517 Score = 47.8 bits (112), Expect = 3e-05 Identities = 33/80 (41%), Positives = 47/80 (58%), Gaps = 3/80 (3%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRVLGTFG--YHAPEYAMTGQLSSK 474 D+ + NVL+ D ++ KIADF L+ + + RV F + APE A + S K Sbjct: 370 DLAARNVLVGDGNIVKIADFGLARLIKEDE---YEARVGARFPIKWTAPEAANYSKFSIK 426 Query: 473 SDVYSFGVVLLELLT-GRKP 417 SDV+SFG++L EL+T GR P Sbjct: 427 SDVWSFGILLTELVTYGRIP 446
>YES_MOUSE (Q04736) Proto-oncogene tyrosine-protein kinase Yes (EC 2.7.10.2)| (p61-Yes) (c-Yes) Length = 540 Score = 47.4 bits (111), Expect = 4e-05 Identities = 30/80 (37%), Positives = 49/80 (61%), Gaps = 3/80 (3%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRVLGTFG--YHAPEYAMTGQLSSK 474 D++++N+L+ + + KIADF L+ D ++ R F + APE A+ G+ + K Sbjct: 393 DLRAANILVGENLICKIADFGLARLIEDNE---YTARQGAKFPIKWTAPEAALYGRFTIK 449 Query: 473 SDVYSFGVVLLELLT-GRKP 417 SDV+SFG++ EL+T GR P Sbjct: 450 SDVWSFGILQTELVTKGRVP 469
>TLK1_MOUSE (Q8C0V0) Serine/threonine-protein kinase tousled-like 1 (EC| 2.7.11.1) (Tousled-like kinase 1) Length = 766 Score = 47.4 bits (111), Expect = 4e-05 Identities = 34/101 (33%), Positives = 52/101 (51%), Gaps = 11/101 (10%) Frame = -2 Query: 647 DIKSSNVLLFDEDVA---KIADFDLSNQAPDMAARLH----STRVLGTFGYHAPEYAMTG 489 D+K N+LL D KI DF LS D + + +++ GT+ Y PE + G Sbjct: 586 DLKPGNILLVDGTACGEIKITDFGLSKIMDDDSYGVDGMDLTSQGAGTYWYLPPECFVVG 645 Query: 488 Q----LSSKSDVYSFGVVLLELLTGRKPVDHTLPRGQQSLV 378 + +S+K DV+S GV+ + L GRKP H + QQ ++ Sbjct: 646 KEPPKISNKVDVWSVGVIFFQCLYGRKPFGHN--QSQQDIL 684
>TLK1_HUMAN (Q9UKI8) Serine/threonine-protein kinase tousled-like 1 (EC| 2.7.11.1) (Tousled-like kinase 1) (PKU-beta) Length = 766 Score = 47.4 bits (111), Expect = 4e-05 Identities = 34/101 (33%), Positives = 52/101 (51%), Gaps = 11/101 (10%) Frame = -2 Query: 647 DIKSSNVLLFDEDVA---KIADFDLSNQAPDMAARLH----STRVLGTFGYHAPEYAMTG 489 D+K N+LL D KI DF LS D + + +++ GT+ Y PE + G Sbjct: 586 DLKPGNILLVDGTACGEIKITDFGLSKIMDDDSYGVDGMDLTSQGAGTYWYLPPECFVVG 645 Query: 488 Q----LSSKSDVYSFGVVLLELLTGRKPVDHTLPRGQQSLV 378 + +S+K DV+S GV+ + L GRKP H + QQ ++ Sbjct: 646 KEPPKISNKVDVWSVGVIFFQCLYGRKPFGHN--QSQQDIL 684
>MOS_CHICK (P10741) Serine/threonine-protein kinase mos (EC 2.7.11.1) (Oocyte| maturation factor mos) Length = 349 Score = 47.4 bits (111), Expect = 4e-05 Identities = 22/78 (28%), Positives = 45/78 (57%), Gaps = 1/78 (1%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHST-RVLGTFGYHAPEYAMTGQLSSKS 471 D+K +N+L+ + KI DF S + + ++ H + GT+ + APE ++++K+ Sbjct: 205 DLKPANILITEHGACKIGDFGCSQRLEEGLSQSHHVCQQGGTYTHRAPELLKGERVTAKA 264 Query: 470 DVYSFGVVLLELLTGRKP 417 D+YSF + L +++ +P Sbjct: 265 DIYSFAITLWQIVMREQP 282
>HEP_DROME (Q23977) Dual specificity mitogen-activated protein kinase kinase| hemipterous (EC 2.7.12.2) (MAPKK) Length = 1178 Score = 47.4 bits (111), Expect = 4e-05 Identities = 28/81 (34%), Positives = 43/81 (53%), Gaps = 2/81 (2%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRVLGTFGYHAPEYA--MTGQLSSK 474 D+K SN+L+ + K+ DF +S + D A +TR G Y APE + + Sbjct: 320 DVKPSNILIDERGNIKLCDFGISGRLVDSKA---NTRSAGCAAYMAPERIDPKKPKYDIR 376 Query: 473 SDVYSFGVVLLELLTGRKPVD 411 +DV+S G+ L+EL T R P + Sbjct: 377 ADVWSLGITLVELATARSPYE 397
>MP2K5_MOUSE (Q9WVS7) Dual specificity mitogen-activated protein kinase kinase 5| (EC 2.7.12.2) (MAP kinase kinase 5) (MAPKK 5) (MAPK/ERK kinase 5) Length = 448 Score = 47.4 bits (111), Expect = 4e-05 Identities = 31/90 (34%), Positives = 46/90 (51%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRVLGTFGYHAPEYAMTGQLSSKSD 468 D+K SN+L+ K+ DF +S Q + A+ + +GT Y APE Q SD Sbjct: 283 DVKPSNMLVNTGGQVKLCDFGVSTQLVNSIAKTY----VGTNAYMAPERISGEQYGIHSD 338 Query: 467 VYSFGVVLLELLTGRKPVDHTLPRGQQSLV 378 V+S G+ +EL GR P + + Q SL+ Sbjct: 339 VWSLGISFMELALGRFPYPQ-IQKNQGSLM 367
>KKCC1_RAT (P97756) Calcium/calmodulin-dependent protein kinase kinase 1 (EC| 2.7.11.17) (Calcium/calmodulin-dependent protein kinase kinase alpha) (CaM-kinase kinase alpha) (CaM-KK alpha) (CaMKK alpha) (alpha CaMKK) (CaMKK 1) (CaM-kinase IV kinase) Length = 505 Score = 47.4 bits (111), Expect = 4e-05 Identities = 37/80 (46%), Positives = 48/80 (60%), Gaps = 3/80 (3%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRVLGTFGYHAPE-YAMTGQ-LSSK 474 DIK SN+LL D+ KIADF +SNQ A+L ST GT + APE + TGQ S K Sbjct: 275 DIKPSNLLLGDDGHVKIADFGVSNQFEGNDAQLSST--AGTPAFMAPEAISDTGQSFSGK 332 Query: 473 S-DVYSFGVVLLELLTGRKP 417 + DV++ GV L + G+ P Sbjct: 333 ALDVWATGVTLYCFVYGKCP 352
>SPK1_DUGTI (P42687) Tyrosine-protein kinase SPK-1 (EC 2.7.10.2)| Length = 497 Score = 47.4 bits (111), Expect = 4e-05 Identities = 23/73 (31%), Positives = 42/73 (57%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRVLGTFGYHAPEYAMTGQLSSKSD 468 D+++ N+L+ ++ K+ADF L+ + + + APE A + +SKSD Sbjct: 342 DLRADNILVANDLTRKVADFGLTELTDGSLGDQEKKTLRFPYKWTAPEAAKSKVFTSKSD 401 Query: 467 VYSFGVVLLELLT 429 V+S+G+V+ E+LT Sbjct: 402 VWSYGIVMFEILT 414
>KCCS_MALDO (Q07250) Calcium/calmodulin-dependent serine/threonine-protein| kinase (EC 2.7.11.17) Length = 415 Score = 47.4 bits (111), Expect = 4e-05 Identities = 34/96 (35%), Positives = 49/96 (51%), Gaps = 6/96 (6%) Frame = -2 Query: 647 DIKSSNVLLFDEDV---AKIADFDLSNQAPDMAARLHSTRVLGTFG---YHAPEYAMTGQ 486 D+K N L D V KI DF LS+ + V+G FG Y +PE GQ Sbjct: 173 DLKPENCLFLDNTVDSPLKIMDFGLSS------VEEFTDPVVGLFGSIDYVSPEALSQGQ 226 Query: 485 LSSKSDVYSFGVVLLELLTGRKPVDHTLPRGQQSLV 378 ++SKSD+++ GV+L LL+G P R +Q ++ Sbjct: 227 VTSKSDMWALGVILYILLSGYPPFIAQSNRQKQQMI 262
>SRK4_SPOLA (P42690) Tyrosine-protein kinase isoform SRK4 (EC 2.7.10.2)| Length = 506 Score = 47.4 bits (111), Expect = 4e-05 Identities = 28/80 (35%), Positives = 48/80 (60%), Gaps = 3/80 (3%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRVLGTFG--YHAPEYAMTGQLSSK 474 D+ + N+L+ + + K+ADF L+ + ++ ++ F + APE AM + + K Sbjct: 359 DLAARNILVGEHKICKVADFGLARVIDE---EIYEAKLGAKFPIKWTAPEAAMYSRFTIK 415 Query: 473 SDVYSFGVVLLELLT-GRKP 417 SDV+SFG+VL E++T GR P Sbjct: 416 SDVWSFGIVLYEVITYGRFP 435
>CDC15_YEAST (P27636) Cell division control protein 15 (EC 2.7.11.1)| Length = 974 Score = 47.0 bits (110), Expect = 5e-05 Identities = 27/77 (35%), Positives = 41/77 (53%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRVLGTFGYHAPEYAMTGQLSSKSD 468 DIK++N+LL ++ K+ADF +S A L GT + APE S+ SD Sbjct: 146 DIKAANILLSADNTVKLADFGVSTIVNSSALTL-----AGTLNWMAPEILGNRGASTLSD 200 Query: 467 VYSFGVVLLELLTGRKP 417 ++S G ++E+LT P Sbjct: 201 IWSLGATVVEMLTKNPP 217
>YES_CANFA (Q28923) Proto-oncogene tyrosine-protein kinase Yes (EC 2.7.10.2)| (p61-Yes) (c-Yes) Length = 538 Score = 47.0 bits (110), Expect = 5e-05 Identities = 31/80 (38%), Positives = 48/80 (60%), Gaps = 3/80 (3%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRVLGTFG--YHAPEYAMTGQLSSK 474 D++++N+L+ + V KIADF L+ D ++ R F + APE A+ G+ + K Sbjct: 391 DLRAANILVGENLVCKIADFGLARLIEDNE---YTARQGAKFPIKWTAPEAALYGRFTIK 447 Query: 473 SDVYSFGVVLLELLT-GRKP 417 SDV+SFG++ EL T GR P Sbjct: 448 SDVWSFGILQTELTTKGRVP 467
>CHK1_YEAST (P38147) Serine/threonine-protein kinase CHK1 (EC 2.7.11.1)| (Checkpoint kinase 1) Length = 527 Score = 47.0 bits (110), Expect = 5e-05 Identities = 45/164 (27%), Positives = 71/164 (43%), Gaps = 5/164 (3%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLH-STRVLGTFGYHAPE--YAMTGQLSS 477 DIK N+LL K+ADF L++Q L S G+ Y APE Y+ G + Sbjct: 142 DIKPENILLDKNGNLKLADFGLASQFRRKDGTLRVSMDQRGSPPYMAPEVLYSEEGYYAD 201 Query: 476 KSDVYSFGVVLLELLTGRKPVDHTLPRGQQSLVTWATPRLSEDKVRQCVDSRLGGDYPPX 297 ++D++S G++L LLTG+ P W P L + +++ ++ P Sbjct: 202 RTDIWSIGILLFVLLTGQTP--------------WELPSLENEDFVFFIENDGNLNWGPW 247 Query: 296 XXXXXXXXXALCVQYEADFRPNMSIVVKALQ--PLLNARAAHPG 171 L + D PN + +KAL+ P + RA+ G Sbjct: 248 SKIEFTHLNLLRKILQPD--PNKRVTLKALKLHPWVLRRASFSG 289
>DSOR1_DROME (Q24324) Dual specificity mitogen-activated protein kinase kinase| dSOR1 (EC 2.7.12.2) (Downstream of RAF) (MAPKK) Length = 396 Score = 47.0 bits (110), Expect = 5e-05 Identities = 27/78 (34%), Positives = 40/78 (51%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRVLGTFGYHAPEYAMTGQLSSKSD 468 D+K SN+L+ KI DF +S Q D A +GT Y +PE S +SD Sbjct: 209 DVKPSNILVNSSGEIKICDFGVSGQLIDSMAN----SFVGTRSYMSPERLQGTHYSVQSD 264 Query: 467 VYSFGVVLLELLTGRKPV 414 ++S G+ L+E+ G P+ Sbjct: 265 IWSLGLSLVEMAIGMYPI 282
>KAPC_YEAST (P05986) cAMP-dependent protein kinase type 3 (EC 2.7.11.11) (PKA| 3) Length = 398 Score = 47.0 bits (110), Expect = 5e-05 Identities = 28/77 (36%), Positives = 37/77 (48%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRVLGTFGYHAPEYAMTGQLSSKSD 468 D+K N+LL KI DF + PD+ L GT Y APE T + D Sbjct: 211 DLKPENILLDKNGHIKITDFGFAKYVPDVTYTL-----CGTPDYIAPEVVSTKPYNKSVD 265 Query: 467 VYSFGVVLLELLTGRKP 417 +SFGV++ E+L G P Sbjct: 266 WWSFGVLIYEMLAGYTP 282
>CSK_RAT (P32577) Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase)| Length = 450 Score = 47.0 bits (110), Expect = 5e-05 Identities = 30/80 (37%), Positives = 49/80 (61%), Gaps = 3/80 (3%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRVLGTFG--YHAPEYAMTGQLSSK 474 D+ + NVL+ +++VAK++DF L+ +A ST+ G + APE + S+K Sbjct: 314 DLAARNVLVSEDNVAKVSDFGLTKEAS-------STQDTGKLPVKWTAPEALREKKFSTK 366 Query: 473 SDVYSFGVVLLELLT-GRKP 417 SDV+SFG++L E+ + GR P Sbjct: 367 SDVWSFGILLWEIYSFGRVP 386
>CSK_MOUSE (P41241) Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase)| (Protein-tyrosine kinase MPK-2) (p50CSK) Length = 450 Score = 47.0 bits (110), Expect = 5e-05 Identities = 30/80 (37%), Positives = 49/80 (61%), Gaps = 3/80 (3%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRVLGTFG--YHAPEYAMTGQLSSK 474 D+ + NVL+ +++VAK++DF L+ +A ST+ G + APE + S+K Sbjct: 314 DLAARNVLVSEDNVAKVSDFGLTKEAS-------STQDTGKLPVKWTAPEALREKKFSTK 366 Query: 473 SDVYSFGVVLLELLT-GRKP 417 SDV+SFG++L E+ + GR P Sbjct: 367 SDVWSFGILLWEIYSFGRVP 386
>CSK_HUMAN (P41240) Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase)| (Protein-tyrosine kinase CYL) Length = 450 Score = 47.0 bits (110), Expect = 5e-05 Identities = 30/80 (37%), Positives = 49/80 (61%), Gaps = 3/80 (3%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRVLGTFG--YHAPEYAMTGQLSSK 474 D+ + NVL+ +++VAK++DF L+ +A ST+ G + APE + S+K Sbjct: 314 DLAARNVLVSEDNVAKVSDFGLTKEAS-------STQDTGKLPVKWTAPEALREKKFSTK 366 Query: 473 SDVYSFGVVLLELLT-GRKP 417 SDV+SFG++L E+ + GR P Sbjct: 367 SDVWSFGILLWEIYSFGRVP 386
>SRC64_DROME (P00528) Tyrosine-protein kinase Src64B (EC 2.7.10.2) (Dsrc64)| Length = 552 Score = 47.0 bits (110), Expect = 5e-05 Identities = 29/74 (39%), Positives = 44/74 (59%), Gaps = 1/74 (1%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQ-APDMAARLHSTRVLGTFGYHAPEYAMTGQLSSKS 471 D+ + NVL+ + +VAKI DF L+ A D +R + APE + G+ S KS Sbjct: 404 DLAARNVLIGENNVAKICDFGLARVIADDEYCPKQGSRF--PVKWTAPEAIIYGKFSIKS 461 Query: 470 DVYSFGVVLLELLT 429 DV+S+G++L+EL T Sbjct: 462 DVWSYGILLMELFT 475
>CLA4_YEAST (P48562) Serine/threonine-protein kinase CLA4 (EC 2.7.11.1)| Length = 842 Score = 47.0 bits (110), Expect = 5e-05 Identities = 32/98 (32%), Positives = 48/98 (48%), Gaps = 1/98 (1%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRVLGTFGYHAPEYAMTGQLSSKSD 468 DIKS NVLL KI DF + D ++ ++GT + APE + K D Sbjct: 693 DIKSDNVLLDTRARVKITDFGFCARLTDKRSK--RATMVGTPYWMAPEVVKQREYDEKID 750 Query: 467 VYSFGVVLLELLTGRKPVDHTLP-RGQQSLVTWATPRL 357 V+S G++ +E+L G P + P + + T TP+L Sbjct: 751 VWSLGIMTIEMLEGEPPYLNEDPLKALYLIATNGTPKL 788
>NEK9_XENLA (Q7ZZC8) Serine/threonine-protein kinase Nek9 (EC 2.7.11.1)| (NimA-related protein kinase 9) (XNek9) (Nercc1 kinase) Length = 944 Score = 47.0 bits (110), Expect = 5e-05 Identities = 28/83 (33%), Positives = 44/83 (53%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRVLGTFGYHAPEYAMTGQLSSKSD 468 DIK+ N+ L ++ K+ D+ L+ Q + + +GT Y +PE + S KSD Sbjct: 158 DIKTLNIFLTKANLIKLGDYGLAKQLSSEYSMAETC--VGTLYYMSPEICQGVKYSFKSD 215 Query: 467 VYSFGVVLLELLTGRKPVDHTLP 399 +++ G VL ELLT + D T P Sbjct: 216 IWAVGCVLYELLTLTRTFDATNP 238
>PAK1_CAEEL (Q17850) Serine/threonine-protein kinase pak-1 (EC 2.7.11.1)| (p21-activated kinase 1) (PAK1) (CePAK) Length = 572 Score = 46.6 bits (109), Expect = 7e-05 Identities = 28/78 (35%), Positives = 42/78 (53%), Gaps = 1/78 (1%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQ-APDMAARLHSTRVLGTFGYHAPEYAMTGQLSSKS 471 DIKS N+LL + K+ DF Q +P+ R T ++GT + APE Q K Sbjct: 414 DIKSDNILLGMDGSVKLTDFGFCAQLSPEQRKR---TTMVGTPYWMAPEVVTRKQYGPKV 470 Query: 470 DVYSFGVVLLELLTGRKP 417 DV+S G++ +E++ G P Sbjct: 471 DVWSLGIMAIEMVEGEPP 488
>M3K7_MOUSE (Q62073) Mitogen-activated protein kinase kinase kinase 7 (EC| 2.7.11.25) (Transforming growth factor-beta-activated kinase 1) (TGF-beta-activated kinase 1) Length = 579 Score = 46.6 bits (109), Expect = 7e-05 Identities = 48/165 (29%), Positives = 68/165 (41%), Gaps = 4/165 (2%) Frame = -2 Query: 647 DIKSSNVLLF-DEDVAKIADFDLSNQAPDMAARLHSTRVLGTFGYHAPEYAMTGQLSSKS 471 D+K N+LL V KI DF A D+ + H T G+ + APE S K Sbjct: 156 DLKPPNLLLVAGGTVLKICDF---GTACDI--QTHMTNNKGSAAWMAPEVFEGSNYSEKC 210 Query: 470 DVYSFGVVLLELLTGRKPVDHTLPRGQQSLVTWATPRLSEDKVRQCVDSRLGGDYPPXXX 291 DV+S+G++L E++T RKP D G + WA G PP Sbjct: 211 DVFSWGIILWEVITRRKPFDEI--GGPAFRIMWAVH---------------NGTRPPLIK 253 Query: 290 XXXXXXXAL---CVQYEADFRPNMSIVVKALQPLLNARAAHPGAE 165 +L C + RP+M +VK + L+ PGA+ Sbjct: 254 NLPKPIESLMTRCWSKDPSQRPSMEEIVKIMTHLMR---YFPGAD 295
>M3K7_HUMAN (O43318) Mitogen-activated protein kinase kinase kinase 7 (EC| 2.7.11.25) (Transforming growth factor-beta-activated kinase 1) (TGF-beta-activated kinase 1) Length = 606 Score = 46.6 bits (109), Expect = 7e-05 Identities = 48/165 (29%), Positives = 68/165 (41%), Gaps = 4/165 (2%) Frame = -2 Query: 647 DIKSSNVLLF-DEDVAKIADFDLSNQAPDMAARLHSTRVLGTFGYHAPEYAMTGQLSSKS 471 D+K N+LL V KI DF A D+ + H T G+ + APE S K Sbjct: 156 DLKPPNLLLVAGGTVLKICDF---GTACDI--QTHMTNNKGSAAWMAPEVFEGSNYSEKC 210 Query: 470 DVYSFGVVLLELLTGRKPVDHTLPRGQQSLVTWATPRLSEDKVRQCVDSRLGGDYPPXXX 291 DV+S+G++L E++T RKP D G + WA G PP Sbjct: 211 DVFSWGIILWEVITRRKPFDEI--GGPAFRIMWAVH---------------NGTRPPLIK 253 Query: 290 XXXXXXXAL---CVQYEADFRPNMSIVVKALQPLLNARAAHPGAE 165 +L C + RP+M +VK + L+ PGA+ Sbjct: 254 NLPKPIESLMTRCWSKDPSQRPSMEEIVKIMTHLMR---YFPGAD 295
>PAK2_RAT (Q64303) Serine/threonine-protein kinase PAK 2 (EC 2.7.11.1)| (p21-activated kinase 2) (PAK-2) (Gamma-PAK) (p62-PAK) Length = 524 Score = 46.6 bits (109), Expect = 7e-05 Identities = 33/99 (33%), Positives = 49/99 (49%), Gaps = 2/99 (2%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQ-APDMAARLHSTRVLGTFGYHAPEYAMTGQLSSKS 471 DIKS NVLL E K+ DF Q P+ + R + ++GT + APE K Sbjct: 368 DIKSDNVLLGMEGSVKLTDFGFCAQITPEQSKR---STMVGTPYWMAPEVVTRKAYGPKV 424 Query: 470 DVYSFGVVLLELLTGRKPVDHTLP-RGQQSLVTWATPRL 357 D++S G++ +E++ G P + P R + T TP L Sbjct: 425 DIWSLGIMAIEMVEGEPPYLNENPLRALYLIATNGTPEL 463
>PAK2_RABIT (Q29502) Serine/threonine-protein kinase PAK 2 (EC 2.7.11.1)| (p21-activated kinase 2) (PAK-2) (Gamma-PAK) (p21-activated protein kinase I) (PAKI) Length = 524 Score = 46.6 bits (109), Expect = 7e-05 Identities = 33/99 (33%), Positives = 49/99 (49%), Gaps = 2/99 (2%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQ-APDMAARLHSTRVLGTFGYHAPEYAMTGQLSSKS 471 DIKS NVLL E K+ DF Q P+ + R + ++GT + APE K Sbjct: 368 DIKSDNVLLGMEGSVKLTDFGFCAQITPEQSKR---STMVGTPYWMAPEVVTRKAYGPKV 424 Query: 470 DVYSFGVVLLELLTGRKPVDHTLP-RGQQSLVTWATPRL 357 D++S G++ +E++ G P + P R + T TP L Sbjct: 425 DIWSLGIMAIEMVEGEPPYLNENPLRALYLIATNGTPEL 463
>PAK2_MOUSE (Q8CIN4) Serine/threonine-protein kinase PAK 2 (EC 2.7.11.1)| (p21-activated kinase 2) (PAK-2) Length = 524 Score = 46.6 bits (109), Expect = 7e-05 Identities = 33/99 (33%), Positives = 49/99 (49%), Gaps = 2/99 (2%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQ-APDMAARLHSTRVLGTFGYHAPEYAMTGQLSSKS 471 DIKS NVLL E K+ DF Q P+ + R + ++GT + APE K Sbjct: 368 DIKSDNVLLGMEGSVKLTDFGFCAQITPEQSKR---STMVGTPYWMAPEVVTRKAYGPKV 424 Query: 470 DVYSFGVVLLELLTGRKPVDHTLP-RGQQSLVTWATPRL 357 D++S G++ +E++ G P + P R + T TP L Sbjct: 425 DIWSLGIMAIEMVEGEPPYLNENPLRALYLIATNGTPEL 463
>PAK2_HUMAN (Q13177) Serine/threonine-protein kinase PAK 2 (EC 2.7.11.1)| (p21-activated kinase 2) (PAK-2) (PAK65) (Gamma-PAK) (S6/H4 kinase) Length = 524 Score = 46.6 bits (109), Expect = 7e-05 Identities = 33/99 (33%), Positives = 49/99 (49%), Gaps = 2/99 (2%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQ-APDMAARLHSTRVLGTFGYHAPEYAMTGQLSSKS 471 DIKS NVLL E K+ DF Q P+ + R + ++GT + APE K Sbjct: 368 DIKSDNVLLGMEGSVKLTDFGFCAQITPEQSKR---STMVGTPYWMAPEVVTRKAYGPKV 424 Query: 470 DVYSFGVVLLELLTGRKPVDHTLP-RGQQSLVTWATPRL 357 D++S G++ +E++ G P + P R + T TP L Sbjct: 425 DIWSLGIMAIEMVEGEPPYLNENPLRALYLIATNGTPEL 463
>KKCC1_MOUSE (Q8VBY2) Calcium/calmodulin-dependent protein kinase kinase 1 (EC| 2.7.11.17) (Calcium/calmodulin-dependent protein kinase kinase alpha) (CaM-kinase kinase alpha) (CaM-KK alpha) (CaMKK alpha) (CaMKK 1) (CaM-kinase IV kinase) Length = 505 Score = 46.6 bits (109), Expect = 7e-05 Identities = 45/109 (41%), Positives = 62/109 (56%), Gaps = 9/109 (8%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRVLGTFGYHAPE-YAMTGQ-LSSK 474 DIK SN+LL D+ KIADF +SNQ A+L ST GT + APE + +GQ S K Sbjct: 275 DIKPSNLLLGDDGHVKIADFGVSNQFEGNDAQLSST--AGTPAFMAPEAISDSGQSFSGK 332 Query: 473 S-DVYSFGVVLLELLTGRKP-VDH---TLPR--GQQSLVTWATPRLSED 348 + DV++ GV L + G+ P +D TL R +++V P +SED Sbjct: 333 ALDVWATGVTLYCFVYGKCPFIDDYILTLHRKIKNEAVVFPEEPEVSED 381
>KAPA_YEAST (P06244) cAMP-dependent protein kinase type 1 (EC 2.7.11.11) (PKA| 1) (CDC25-suppressing protein kinase) (PK-25) Length = 397 Score = 46.6 bits (109), Expect = 7e-05 Identities = 27/77 (35%), Positives = 37/77 (48%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRVLGTFGYHAPEYAMTGQLSSKSD 468 D+K N+LL KI DF + PD+ L GT Y APE T + D Sbjct: 210 DLKPENILLDKNGHIKITDFGFAKYVPDVTYTL-----CGTPDYIAPEVVSTKPYNKSID 264 Query: 467 VYSFGVVLLELLTGRKP 417 +SFG+++ E+L G P Sbjct: 265 WWSFGILIYEMLAGYTP 281
>CSK_CHICK (P41239) Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase)| Length = 450 Score = 46.6 bits (109), Expect = 7e-05 Identities = 29/80 (36%), Positives = 49/80 (61%), Gaps = 3/80 (3%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRVLGTFG--YHAPEYAMTGQLSSK 474 D+ + NVL+ ++++AK++DF L+ +A ST+ G + APE + S+K Sbjct: 314 DLAARNVLVSEDNIAKVSDFGLTKEAS-------STQDTGKLPVKWTAPEALREKKFSTK 366 Query: 473 SDVYSFGVVLLELLT-GRKP 417 SDV+SFG++L E+ + GR P Sbjct: 367 SDVWSFGILLWEIYSFGRVP 386
>FUZ7_USTMA (Q99078) Dual specificity protein kinase FUZ7 (EC 2.7.12.2)| Length = 435 Score = 46.6 bits (109), Expect = 7e-05 Identities = 28/77 (36%), Positives = 41/77 (53%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRVLGTFGYHAPEYAMTGQLSSKSD 468 D+K SN+L+ KI DF +S + + A +GT Y +PE Q S KSD Sbjct: 231 DVKPSNILVNGAGQIKICDFGVSGELINSIA----DTFVGTSTYMSPERIQGDQYSVKSD 286 Query: 467 VYSFGVVLLELLTGRKP 417 V+S GV ++++ GR P Sbjct: 287 VWSLGVSIIDVALGRFP 303
>CLA4_CANAL (O14427) Serine/threonine-protein kinase CLA4 (EC 2.7.11.1)| Length = 971 Score = 46.6 bits (109), Expect = 7e-05 Identities = 32/103 (31%), Positives = 50/103 (48%), Gaps = 1/103 (0%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRVLGTFGYHAPEYAMTGQLSSKSD 468 DIKS NVLL KI DF + D R ++GT + APE + K D Sbjct: 803 DIKSDNVLLDAYGNVKITDFGFCAKLTDQ--RNKRATMVGTPYWMAPEVVKQKEYDEKVD 860 Query: 467 VYSFGVVLLELLTGRKPVDHTLP-RGQQSLVTWATPRLSEDKV 342 V+S G++ +E++ G P + P + + T TP+L + ++ Sbjct: 861 VWSLGIMTIEMIEGEPPYLNEEPLKALYLIATNGTPKLKKPEL 903
>MKK2_YEAST (P32491) MAP kinase kinase MKK2/SSP33 (EC 2.7.12.2)| Length = 506 Score = 46.2 bits (108), Expect = 9e-05 Identities = 29/79 (36%), Positives = 41/79 (51%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRVLGTFGYHAPEYAMTGQLSSKSD 468 DIK N+LL ++ K+ DF +S +A + A + GT Y APE S D Sbjct: 342 DIKPQNILLNEKGEIKLCDFGVSGEAVNSLAMTFT----GTSFYMAPERIQGQPYSVTCD 397 Query: 467 VYSFGVVLLELLTGRKPVD 411 V+S G+ LLE+ GR P + Sbjct: 398 VWSLGLTLLEVAGGRFPFE 416
>LRRK1_MOUSE (Q3UHC2) Leucine-rich repeat serine/threonine-protein kinase 1 (EC| 2.7.11.1) Length = 2014 Score = 46.2 bits (108), Expect = 9e-05 Identities = 29/82 (35%), Positives = 45/82 (54%), Gaps = 5/82 (6%) Frame = -2 Query: 647 DIKSSNVLLFDEDVA-----KIADFDLSNQAPDMAARLHSTRVLGTFGYHAPEYAMTGQL 483 D+KS N+L++ K++D+ +S Q+ A V GT GY APE Sbjct: 1386 DLKSDNILVWSLSAKEHINIKLSDYGISRQSFHEGA----LGVEGTPGYQAPEIRPRIVY 1441 Query: 482 SSKSDVYSFGVVLLELLTGRKP 417 K D++S+G+VL ELL+G++P Sbjct: 1442 DEKVDMFSYGMVLYELLSGQRP 1463
>PKWA_THECU (P49695) Probable serine/threonine-protein kinase pkwA (EC| 2.7.11.1) Length = 742 Score = 46.2 bits (108), Expect = 9e-05 Identities = 28/77 (36%), Positives = 39/77 (50%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRVLGTFGYHAPEYAMTGQLSSKSD 468 D K SN++L D ++ DF ++ D + S V+GT Y +PE Q+ SD Sbjct: 138 DFKPSNIVLA-ADGPRVIDFGVARPL-DSSVMTQSGAVIGTLAYMSPEQTDGSQVGPASD 195 Query: 467 VYSFGVVLLELLTGRKP 417 V+S G VL TGR P Sbjct: 196 VFSLGTVLAFAATGRSP 212
>KIN1_YEAST (P13185) Protein kinase KIN1 (EC 2.7.11.1)| Length = 1064 Score = 46.2 bits (108), Expect = 9e-05 Identities = 30/80 (37%), Positives = 42/80 (52%), Gaps = 1/80 (1%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRVLGTFGYHAPEYAMTGQLSSKS- 471 D+K N+++ D KI DF LSN D +LH+ G+ + APE + Sbjct: 269 DLKIENIMISDSSEIKIIDFGLSN-IYDSRKQLHT--FCGSLYFAAPELLKANPYTGPEV 325 Query: 470 DVYSFGVVLLELLTGRKPVD 411 DV+SFGVVL L+ G+ P D Sbjct: 326 DVWSFGVVLFVLVCGKVPFD 345
>SPEG_BRARE (Q696W0) Striated muscle preferentially expressed protein kinase (EC| 2.7.11.1) Length = 2995 Score = 46.2 bits (108), Expect = 9e-05 Identities = 26/84 (30%), Positives = 46/84 (54%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRVLGTFGYHAPEYAMTGQLSSKSD 468 DIK N+++ + +V KI DF + + ++ + +R LGT Y APE + +D Sbjct: 2801 DIKPDNIMVTNLNVIKIIDFGSAQRFNPLSLQ-QCSRYLGTLEYMAPEMLKGDLVGPPAD 2859 Query: 467 VYSFGVVLLELLTGRKPVDHTLPR 396 ++S GV+ +L+GR P + P+ Sbjct: 2860 IWSLGVLSYIMLSGRHPFEDKDPQ 2883 Score = 30.8 bits (68), Expect = 3.8 Identities = 22/81 (27%), Positives = 35/81 (43%), Gaps = 4/81 (4%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRVL----GTFGYHAPEYAMTGQLS 480 D+K N+L+ D+ +I D N A ++ L G + APE +S Sbjct: 1372 DLKPENILMADQKTDQIRICDFGN-----ALKVKPNEELYCKYGIPEFIAPEIVNQSPIS 1426 Query: 479 SKSDVYSFGVVLLELLTGRKP 417 +D++ GV+ LTG P Sbjct: 1427 KSTDIWPVGVITYLCLTGVSP 1447
>KSYK_RAT (Q64725) Tyrosine-protein kinase SYK (EC 2.7.10.2) (Spleen tyrosine| kinase) Length = 629 Score = 46.2 bits (108), Expect = 9e-05 Identities = 44/146 (30%), Positives = 67/146 (45%), Gaps = 3/146 (2%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRVLGTFG--YHAPEYAMTGQLSSK 474 D+ + NVLL + AKI+DF LS +A + + G + ++APE + SSK Sbjct: 488 DLAARNVLLVTQHYAKISDFGLS-KALRADENYYKAQTHGKWPVKWYAPECINYFKFSSK 546 Query: 473 SDVYSFGVVLLELLT-GRKPVDHTLPRGQQSLVTWATPRLSEDKVRQCVDSRLGGDYPPX 297 SDV+SFGV++ E + G+KP RG + + T L + + C PP Sbjct: 547 SDVWSFGVLMWEAFSYGQKPY-----RGMKG--SEVTAMLEKGERMGC---------PPG 590 Query: 296 XXXXXXXXXALCVQYEADFRPNMSIV 219 LC Y+ + RP + V Sbjct: 591 CPREMYDLMFLCWTYDVENRPGFAAV 616
>SKH1_SCHPO (Q9Y884) MAP kinase kinase skh1/pek1 (EC 2.7.12.2)| Length = 363 Score = 46.2 bits (108), Expect = 9e-05 Identities = 27/77 (35%), Positives = 40/77 (51%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRVLGTFGYHAPEYAMTGQLSSKSD 468 DIK SN+LL + K+ DF +S + + A + GT Y APE G + SD Sbjct: 206 DIKPSNILLTSKGQVKLCDFGVSGELVNSLAGTFT----GTSYYMAPERISGGSYTISSD 261 Query: 467 VYSFGVVLLELLTGRKP 417 ++S G+ L+E+ R P Sbjct: 262 IWSLGLTLMEVALNRFP 278
>PLK4_MOUSE (Q64702) Serine/threonine-protein kinase PLK4 (EC 2.7.11.21)| (Polo-like kinase 4) (PLK-4) (Serine/threonine-protein kinase Sak) (Serine/threonine-protein kinase 18) Length = 925 Score = 46.2 bits (108), Expect = 9e-05 Identities = 31/79 (39%), Positives = 41/79 (51%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRVLGTFGYHAPEYAMTGQLSSKSD 468 D+ SN+LL KIADF L+ Q +M H T + GT Y +PE A +SD Sbjct: 136 DLTLSNILLTRNMNIKIADFGLATQL-NMPHEKHYT-LCGTPNYISPEIATRSAHGLESD 193 Query: 467 VYSFGVVLLELLTGRKPVD 411 ++S G + LL GR P D Sbjct: 194 IWSLGCMFYTLLIGRPPFD 212
>ABL_DROME (P00522) Tyrosine-protein kinase Abl (EC 2.7.10.2) (Abelson| protein) (D-ash) Length = 1620 Score = 45.8 bits (107), Expect = 1e-04 Identities = 36/114 (31%), Positives = 53/114 (46%), Gaps = 9/114 (7%) Frame = -2 Query: 647 DIKSSNVLLFDEDVAKIADFDLSNQAPDMAARLHSTRVLGTFGYHAPEYAMTGQLSSKSD 468 D+ + N L+ D + K+ADF L+ D H+ + APE + S+KSD Sbjct: 492 DLAARNCLVGDNKLVKVADFGLARLMRDDTYTAHAGAKF-PIKWTAPEGLAYNKFSTKSD 550 Query: 467 VYSFGVVLLELLT-GRKP--------VDHTLPRGQQSLVTWATPRLSEDKVRQC 333 V++FGV+L E+ T G P V H L +G + P D +RQC Sbjct: 551 VWAFGVLLWEIATYGMSPYPAIDLTDVYHKLDKGYRMERPPGCPPEVYDLMRQC 604 Database: uniprot_sprot.fasta Posted date: May 25, 2006 5:36 PM Number of letters in database: 80,573,946 Number of sequences in database: 219,361 Lambda K H 0.318 0.135 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 93,485,500 Number of Sequences: 219361 Number of extensions: 1882487 Number of successful extensions: 6466 Number of sequences better than 10.0: 500 Number of HSP's better than 10.0 without gapping: 5562 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 5787 length of database: 80,573,946 effective HSP length: 108 effective length of database: 56,882,958 effective search space used: 6484657212 frameshift window, decay const: 50, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
