ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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更新日：2016年5月1日

Clone Information

BLAST Search Result

Clone Name rbasd24j01
Clone Library Name barley_pub
No. Definition Score
(bits)		 E
Value
1PP2C1_SCHPO (P40371) Protein phosphatase 2C homolog 1 (EC 3.1.3.... 70 3e-12
2PP2CL_MOUSE (Q8BHN0) Protein phosphatase 2C isoform epsilon (EC ... 65 2e-10
3PP2CL_HUMAN (Q5SGD2) Protein phosphatase 2C isoform epsilon (EC ... 65 2e-10
4PP2C1_YEAST (P35182) Protein phosphatase 2C homolog 1 (EC 3.1.3.... 63 6e-10
5PP2C1_ARATH (P49597) Protein phosphatase 2C ABI1 (EC 3.1.3.16) (... 60 3e-09
6PP2C2_ARATH (O04719) Protein phosphatase 2C ABI2 (EC 3.1.3.16) (... 59 1e-08
7PP2C_LEICH (P36982) Protein phosphatase 2C (EC 3.1.3.16) (PP2C) 58 2e-08
8PP2C2_CAEEL (P49596) Probable protein phosphatase 2C T23F11.1 (E... 57 5e-08
9PP2C4_ARATH (P49598) Protein phosphatase 2C (EC 3.1.3.16) (PP2C) 57 5e-08
10PP2CA_RAT (P20650) Protein phosphatase 2C isoform alpha (EC 3.1.... 55 2e-07
11PP2CA_RABIT (P35814) Protein phosphatase 2C isoform alpha (EC 3.... 55 2e-07
12PP2CA_MOUSE (P49443) Protein phosphatase 2C isoform alpha (EC 3.... 55 2e-07
13PP2CA_HUMAN (P35813) Protein phosphatase 2C isoform alpha (EC 3.... 55 2e-07
14PP2CA_BOVIN (O62829) Protein phosphatase 2C isoform alpha (EC 3.... 55 2e-07
15PP2C3_ARATH (P49599) Protein phosphatase 2C PPH1 (EC 3.1.3.16) (... 54 2e-07
16PP2CB_MOUSE (P36993) Protein phosphatase 2C isoform beta (EC 3.1... 54 3e-07
17PPM1F_HUMAN (P49593) Ca(2+)/calmodulin-dependent protein kinase ... 54 4e-07
18PP2CB_BOVIN (O62830) Protein phosphatase 2C isoform beta (EC 3.1... 53 7e-07
19PP2CB_HUMAN (O75688) Protein phosphatase 2C isoform beta (EC 3.1... 53 7e-07
20PP2CB_RAT (P35815) Protein phosphatase 2C isoform beta (EC 3.1.3... 52 1e-06
21PP2C4_SCHPO (O14156) Protein phosphatase 2C homolog 4 (EC 3.1.3.... 51 3e-06
22PP2CG_MOUSE (Q61074) Protein phosphatase 2C isoform gamma (EC 3.... 50 6e-06
23PP2CG_HUMAN (O15355) Protein phosphatase 2C isoform gamma (EC 3.... 50 6e-06
24PP2C1_CAEEL (P49595) Probable protein phosphatase 2C F42G9.1 (EC... 49 1e-05
25PP2CG_BOVIN (P79126) Protein phosphatase 2C isoform gamma (EC 3.... 48 2e-05
26PP2C3_SCHPO (Q09173) Protein phosphatase 2C homolog 3 (EC 3.1.3.... 48 2e-05
27PP2C2_SCHPO (Q09172) Protein phosphatase 2C homolog 2 (EC 3.1.3.... 47 3e-05
28PPM1F_MOUSE (Q8CGA0) Ca(2+)/calmodulin-dependent protein kinase ... 47 3e-05
29PP2CE_MOUSE (Q8BU27) Protein phosphatase 2C isoform eta (EC 3.1.... 46 6e-05
30PP2CE_HUMAN (Q96MI6) Protein phosphatase 2C isoform eta (EC 3.1.... 46 8e-05
31PPM1F_RAT (Q9WVR7) Ca(2+)/calmodulin-dependent protein kinase ph... 46 8e-05
32PP2C2_YEAST (P39966) Protein phosphatase 2C homolog 2 (EC 3.1.3.... 45 1e-04
33FEM2_CAEEL (P49594) Ca(2+)/calmodulin-dependent protein kinase p... 45 1e-04
34PP2C3_YEAST (P34221) Protein phosphatase 2C homolog 3 (EC 3.1.3.... 44 2e-04
35CYAA_USTMA (P49606) Adenylate cyclase (EC 4.6.1.1) (ATP pyrophos... 44 4e-04
36PHLPL_HUMAN (Q6ZVD8) PH domain leucine-rich repeat protein phosp... 42 9e-04
37PHLPL_MOUSE (Q8BXA7) PH domain leucine-rich repeat protein phosp... 42 0.002
38PHLPP_RAT (Q9WTR8) PH domain leucine-rich repeat protein phospha... 41 0.003
39PHLPP_HUMAN (O60346) PH domain leucine-rich repeat-containing pr... 41 0.003
40PP2C4_YEAST (P38089) Protein phosphatase 2C homolog 4 (EC 3.1.3.... 40 0.003
41CYAA_PODAN (Q01513) Adenylate cyclase (EC 4.6.1.1) (ATP pyrophos... 40 0.004
42PHLPP_MOUSE (Q8CHE4) PH domain leucine-rich repeat-containing pr... 40 0.004
43CYAA_NEUCR (Q01631) Adenylate cyclase (EC 4.6.1.1) (ATP pyrophos... 40 0.006
44CYAA_SACKL (P23466) Adenylate cyclase (EC 4.6.1.1) (ATP pyrophos... 40 0.006
45PP2CD_MOUSE (Q9QZ67) Protein phosphatase 2C isoform delta (EC 3.... 39 0.008
46PP2C_PARTE (P49444) Protein phosphatase 2C (EC 3.1.3.16) (PP2C) 38 0.017
47CYAA_YEAST (P08678) Adenylate cyclase (EC 4.6.1.1) (ATP pyrophos... 38 0.022
48PP2CD_HUMAN (O15297) Protein phosphatase 2C isoform delta (EC 3.... 37 0.029
49CYAA_SCHPO (P14605) Adenylate cyclase (EC 4.6.1.1) (ATP pyrophos... 36 0.084
50PHLPP_DROME (Q9VJ07) Protein phosphatase PHLPP-like protein (EC ... 35 0.11
51KAPP_ARATH (P46014) Kinase-associated protein phosphatase (EC 3.... 35 0.14
52PDP1_HUMAN (Q9P0J1) [Pyruvate dehydrogenase [lipoamide]]-phospha... 34 0.24
53PDP1_RAT (O88483) [Pyruvate dehydrogenase [lipoamide]]-phosphata... 34 0.24
54PDP1_MOUSE (Q3UV70) [Pyruvate dehydrogenase [lipoamide]]-phospha... 34 0.24
55PDP1_BOVIN (P35816) [Pyruvate dehydrogenase [lipoamide]]-phospha... 34 0.24
56Y2780_ENTFA (Q830K2) UPF0133 protein EF2780 34 0.32
57PDP2_HUMAN (Q9P2J9) [Pyruvate dehydrogenase [lipoamide]]-phospha... 33 0.71
58PP2C5_YEAST (Q12511) Protein phosphatase 2C homolog 5 (EC 3.1.3.... 32 0.93
59PDP2_RAT (O88484) [Pyruvate dehydrogenase [lipoamide]]-phosphata... 31 2.1
60CARD_PECCC (Q9XB58) Carbapenem antibiotics biosynthesis protein ... 31 2.7
61GYRA_BUCAP (Q8K9W2) DNA gyrase subunit A (EC 5.99.1.3) 30 3.5
62G6PI_PSEFL (Q848I4) Glucose-6-phosphate isomerase (EC 5.3.1.9) (... 30 4.6
63PYRD_STRCO (Q9KXR7) Dihydroorotate dehydrogenase (EC 1.3.3.1) (D... 30 6.0 
>PP2C1_SCHPO (P40371) Protein phosphatase 2C homolog 1 (EC 3.1.3.16) (PP2C-1)|
          Length = 347

 Score = 70.5 bits (171), Expect = 3e-12
 Identities = 38/91 (41%), Positives = 59/91 (64%), Gaps = 1/91 (1%)
 Frame = -2

Query: 524 RVCGQLAVSRAFGDRNLKSLLKSEPDVKVEDI-DHTAELVVLASDGVWKVMNNREAVDVV 348
           R+ G LAV+RA GD  LK L+ + P      I +   E  ++A DG+W V++++EAVD V
Sbjct: 231 RINGVLAVTRALGDTYLKELVSAHPFTTETRIWNGHDEFFIIACDGLWDVVSDQEAVDFV 290

Query: 347 KKYKDPQTAAKQLIAEAVKRDSKDDISCVVV 255
           + +  P+ AA +L+  A+KR S D+I+C+VV
Sbjct: 291 RNFVSPREAAVRLVEFALKRLSTDNITCIVV 321
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>PP2CL_MOUSE (Q8BHN0) Protein phosphatase 2C isoform epsilon (EC 3.1.3.16)|
           (PP2C-epsilon) (Protein phosphatase 1L) (Protein
           phosphatase 1-like)
          Length = 360

 Score = 64.7 bits (156), Expect = 2e-10
 Identities = 38/97 (39%), Positives = 60/97 (61%), Gaps = 4/97 (4%)
 Frame = -2

Query: 524 RVCGQLAVSRAFGDRNLKSL--LKSEPDVKVEDIDHTA-ELVVLASDGVWKVMNNREAVD 354
           RV G LA+SR+ GD  LK+L  +  +PD+   D+D    E ++LASDG+W   +N EAV 
Sbjct: 256 RVQGILAMSRSLGDYPLKNLNVVIPDPDILTFDLDKLQPEFMILASDGLWDAFSNEEAVR 315

Query: 353 VVKKYKD-PQTAAKQLIAEAVKRDSKDDISCVVVRFK 246
            +K+  D P   AK ++ ++  R   D+I+ +VV+F+
Sbjct: 316 FIKERLDEPHFGAKSIVLQSFYRGCPDNITVMVVKFR 352
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>PP2CL_HUMAN (Q5SGD2) Protein phosphatase 2C isoform epsilon (EC 3.1.3.16)|
           (PP2C-epsilon) (Protein phosphatase 1L) (Protein
           phosphatase 1-like)
          Length = 360

 Score = 64.7 bits (156), Expect = 2e-10
 Identities = 38/97 (39%), Positives = 60/97 (61%), Gaps = 4/97 (4%)
 Frame = -2

Query: 524 RVCGQLAVSRAFGDRNLKSL--LKSEPDVKVEDIDHTA-ELVVLASDGVWKVMNNREAVD 354
           RV G LA+SR+ GD  LK+L  +  +PD+   D+D    E ++LASDG+W   +N EAV 
Sbjct: 256 RVQGILAMSRSLGDYPLKNLNVVIPDPDILTFDLDKLQPEFMILASDGLWDAFSNEEAVR 315

Query: 353 VVKKYKD-PQTAAKQLIAEAVKRDSKDDISCVVVRFK 246
            +K+  D P   AK ++ ++  R   D+I+ +VV+F+
Sbjct: 316 FIKERLDEPHFGAKSIVLQSFYRGCPDNITVMVVKFR 352
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>PP2C1_YEAST (P35182) Protein phosphatase 2C homolog 1 (EC 3.1.3.16) (PP2C-1)|
          Length = 281

 Score = 62.8 bits (151), Expect = 6e-10
 Identities = 30/90 (33%), Positives = 56/90 (62%)
 Frame = -2

Query: 524 RVCGQLAVSRAFGDRNLKSLLKSEPDVKVEDIDHTAELVVLASDGVWKVMNNREAVDVVK 345
           RV G LAV+R+ GD+   SL+   P     +I    + ++LA DG+W V+++++A +++K
Sbjct: 190 RVNGMLAVTRSLGDKFFDSLVVGSPFTTSVEITSEDKFLILACDGLWDVIDDQDACELIK 249

Query: 344 KYKDPQTAAKQLIAEAVKRDSKDDISCVVV 255
              +P  AAK L+  A++  + D+++ +VV
Sbjct: 250 DITEPNEAAKVLVRYALENGTTDNVTVMVV 279
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>PP2C1_ARATH (P49597) Protein phosphatase 2C ABI1 (EC 3.1.3.16) (PP2C) (Abscisic|
           acid-insensitive 1)
          Length = 434

 Score = 60.5 bits (145), Expect = 3e-09
 Identities = 43/120 (35%), Positives = 60/120 (50%), Gaps = 27/120 (22%)
 Frame = -2

Query: 524 RVCGQLAVSRAFGDRNLKSLLKSEPDVKVEDIDHTAELVVLASDGVWKVMNNREAVDVVK 345
           RV G LA+SR+ GDR LK  +  +P+V         + ++LASDGVW VM + EA ++ +
Sbjct: 304 RVFGVLAMSRSIGDRYLKPSIIPDPEVTAVKRVKEDDCLILASDGVWDVMTDEEACEMAR 363

Query: 344 KY-------------------------KDP--QTAAKQLIAEAVKRDSKDDISCVVVRFK 246
           K                          KDP   +AA+ L   A++R SKD+IS VVV  K
Sbjct: 364 KRILLWHKKNAVAGDASLLADERRKEGKDPAAMSAAEYLSKLAIQRGSKDNISVVVVDLK 423
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>PP2C2_ARATH (O04719) Protein phosphatase 2C ABI2 (EC 3.1.3.16) (PP2C) (Abscisic|
           acid-insensitive 2)
          Length = 423

 Score = 58.5 bits (140), Expect = 1e-08
 Identities = 42/119 (35%), Positives = 59/119 (49%), Gaps = 26/119 (21%)
 Frame = -2

Query: 524 RVCGQLAVSRAFGDRNLKSLLKSEPDVKVEDIDHTAELVVLASDGVWKVMNNREAVDVVK 345
           RV G LA+SR+ GDR LK  +  +P+V         + ++LASDG+W VM N E  D+ +
Sbjct: 294 RVFGVLAMSRSIGDRYLKPSVIPDPEVTSVRRVKEDDCLILASDGLWDVMTNEEVCDLAR 353

Query: 344 KY------------------------KDP--QTAAKQLIAEAVKRDSKDDISCVVVRFK 246
           K                         KDP   +AA+ L   A+++ SKD+IS VVV  K
Sbjct: 354 KRILLWHKKNAMAGEALLPAEKRGEGKDPAAMSAAEYLSKMALQKGSKDNISVVVVDLK 412
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>PP2C_LEICH (P36982) Protein phosphatase 2C (EC 3.1.3.16) (PP2C)|
          Length = 406

 Score = 57.8 bits (138), Expect = 2e-08
 Identities = 45/118 (38%), Positives = 64/118 (54%), Gaps = 16/118 (13%)
 Frame = -2

Query: 551 VSNMPGDVP--RVCGQLAVSRAFGDRNLKSLLKSEPDVKV---EDIDH------TAELVV 405
           + N  G V   RV G LAVSRAFGDR  K    S+ + KV    D+ H      + + V+
Sbjct: 158 IENCAGRVENNRVDGSLAVSRAFGDREYKLGSGSQLEQKVIALADVQHKDFTFDSNDFVL 217

Query: 404 LASDGVWKV-MNNREAVDVVKKY----KDPQTAAKQLIAEAVKRDSKDDISCVVVRFK 246
           L  DGV++    N E V  VK+      D    A ++  EA++R S+D+ISC++V+FK
Sbjct: 218 LCCDGVFEGNFPNEEVVAYVKQQLETCNDLAEVAGRVCEEAIERGSRDNISCMIVQFK 275
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>PP2C2_CAEEL (P49596) Probable protein phosphatase 2C T23F11.1 (EC 3.1.3.16)|
           (PP2C)
          Length = 356

 Score = 56.6 bits (135), Expect = 5e-08
 Identities = 33/93 (35%), Positives = 51/93 (54%), Gaps = 13/93 (13%)
 Frame = -2

Query: 524 RVCGQLAVSRAFGDRNLKS---------LLKSEPDVKVEDIDHTAELVVLASDGVWKVMN 372
           RV G LA+SRA GD   K+         ++ + PDV  + +    E +VLA DG+W VM 
Sbjct: 176 RVNGNLALSRALGDFAFKNCDTKPAEEQIVTAFPDVITDKLTPDHEFIVLACDGIWDVMT 235

Query: 371 NREAVDVVK----KYKDPQTAAKQLIAEAVKRD 285
           N+E VD V+    + +DPQ+  ++L+   +  D
Sbjct: 236 NQEVVDFVREKLAEKRDPQSICEELLTRCLAPD 268
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>PP2C4_ARATH (P49598) Protein phosphatase 2C (EC 3.1.3.16) (PP2C)|
          Length = 399

 Score = 56.6 bits (135), Expect = 5e-08
 Identities = 39/107 (36%), Positives = 52/107 (48%), Gaps = 14/107 (13%)
 Frame = -2

Query: 533 DVPRVCGQLAVSRAFGDRNLKSLLKSEPDVKVEDIDHTAELVVLASDGVWKVMNNREAVD 354
           D  RV G LA+SRA GD  LK  +  +P+V V D     E ++LASDG+W V+ N  A  
Sbjct: 281 DGARVLGVLAMSRAIGDNYLKPYVIPDPEVTVTDRTDEDECLILASDGLWDVVPNETACG 340

Query: 353 VVK--------------KYKDPQTAAKQLIAEAVKRDSKDDISCVVV 255
           V +               +     AA  L   A+ R S D++S VVV
Sbjct: 341 VARMCLRGAGAGDDSDAAHNACSDAALLLTKLALARQSSDNVSVVVV 387
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>PP2CA_RAT (P20650) Protein phosphatase 2C isoform alpha (EC 3.1.3.16)|
           (PP2C-alpha) (IA) (Protein phosphatase 1A)
          Length = 382

 Score = 54.7 bits (130), Expect = 2e-07
 Identities = 33/108 (30%), Positives = 56/108 (51%), Gaps = 14/108 (12%)
 Frame = -2

Query: 530 VPRVCGQLAVSRAFGDRNLK---------SLLKSEPDVK-VEDIDHTAELVVLASDGVWK 381
           + RV G LAVSRA GD + K          L+  EP+V  +E  +   + ++LA DG+W 
Sbjct: 184 IQRVNGSLAVSRALGDFDYKCVHGKGPTEQLVSPEPEVHDIERSEEDDQFIILACDGIWD 243

Query: 380 VMNNREAVDVVKK----YKDPQTAAKQLIAEAVKRDSKDDISCVVVRF 249
           VM N E  D V+       D +    +++   + + S+D++S +++ F
Sbjct: 244 VMGNEELCDFVRSRLEVTDDLEKVCNEVVDTCLYKGSRDNMSVILICF 291
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>PP2CA_RABIT (P35814) Protein phosphatase 2C isoform alpha (EC 3.1.3.16)|
           (PP2C-alpha) (IA) (Protein phosphatase 1A)
          Length = 382

 Score = 54.7 bits (130), Expect = 2e-07
 Identities = 33/108 (30%), Positives = 56/108 (51%), Gaps = 14/108 (12%)
 Frame = -2

Query: 530 VPRVCGQLAVSRAFGDRNLK---------SLLKSEPDVK-VEDIDHTAELVVLASDGVWK 381
           + RV G LAVSRA GD + K          L+  EP+V  +E  +   + ++LA DG+W 
Sbjct: 184 IQRVNGSLAVSRALGDFDYKCVHGKGPTEQLVSPEPEVHDIERSEEDDQFIILACDGIWD 243

Query: 380 VMNNREAVDVVKK----YKDPQTAAKQLIAEAVKRDSKDDISCVVVRF 249
           VM N E  D V+       D +    +++   + + S+D++S +++ F
Sbjct: 244 VMGNEELCDFVRSRLEVTDDLEKVCNEVVDTCLYKGSRDNMSVILICF 291
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>PP2CA_MOUSE (P49443) Protein phosphatase 2C isoform alpha (EC 3.1.3.16)|
           (PP2C-alpha) (IA) (Protein phosphatase 1A)
          Length = 382

 Score = 54.7 bits (130), Expect = 2e-07
 Identities = 33/108 (30%), Positives = 56/108 (51%), Gaps = 14/108 (12%)
 Frame = -2

Query: 530 VPRVCGQLAVSRAFGDRNLK---------SLLKSEPDVK-VEDIDHTAELVVLASDGVWK 381
           + RV G LAVSRA GD + K          L+  EP+V  +E  +   + ++LA DG+W 
Sbjct: 184 IQRVNGSLAVSRALGDFDYKCVHGKGPTEQLVSPEPEVHDIERSEEDDQFIILACDGIWD 243

Query: 380 VMNNREAVDVVKK----YKDPQTAAKQLIAEAVKRDSKDDISCVVVRF 249
           VM N E  D V+       D +    +++   + + S+D++S +++ F
Sbjct: 244 VMGNEELCDFVRSRLEVTDDLEKVCNEVVDTCLYKGSRDNMSVILICF 291
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>PP2CA_HUMAN (P35813) Protein phosphatase 2C isoform alpha (EC 3.1.3.16)|
           (PP2C-alpha) (IA) (Protein phosphatase 1A)
          Length = 382

 Score = 54.7 bits (130), Expect = 2e-07
 Identities = 33/108 (30%), Positives = 56/108 (51%), Gaps = 14/108 (12%)
 Frame = -2

Query: 530 VPRVCGQLAVSRAFGDRNLK---------SLLKSEPDVK-VEDIDHTAELVVLASDGVWK 381
           + RV G LAVSRA GD + K          L+  EP+V  +E  +   + ++LA DG+W 
Sbjct: 184 IQRVNGSLAVSRALGDFDYKCVHGKGPTEQLVSPEPEVHDIERSEEDDQFIILACDGIWD 243

Query: 380 VMNNREAVDVVKK----YKDPQTAAKQLIAEAVKRDSKDDISCVVVRF 249
           VM N E  D V+       D +    +++   + + S+D++S +++ F
Sbjct: 244 VMGNEELCDFVRSRLEVTDDLEKVCNEVVDTCLYKGSRDNMSVILICF 291
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>PP2CA_BOVIN (O62829) Protein phosphatase 2C isoform alpha (EC 3.1.3.16)|
           (PP2C-alpha)
          Length = 382

 Score = 54.7 bits (130), Expect = 2e-07
 Identities = 33/108 (30%), Positives = 56/108 (51%), Gaps = 14/108 (12%)
 Frame = -2

Query: 530 VPRVCGQLAVSRAFGDRNLK---------SLLKSEPDVK-VEDIDHTAELVVLASDGVWK 381
           + RV G LAVSRA GD + K          L+  EP+V  +E  +   + ++LA DG+W 
Sbjct: 184 IQRVNGSLAVSRALGDFDYKCVHGKGPTEQLVSPEPEVHDIERSEEDDQFIILACDGIWD 243

Query: 380 VMNNREAVDVVKK----YKDPQTAAKQLIAEAVKRDSKDDISCVVVRF 249
           VM N E  D V+       D +    +++   + + S+D++S +++ F
Sbjct: 244 VMGNEELCDFVRSRLEVTDDLEKVCNEVVDTCLYKGSRDNMSVILICF 291
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>PP2C3_ARATH (P49599) Protein phosphatase 2C PPH1 (EC 3.1.3.16) (PP2C)|
          Length = 388

 Score = 54.3 bits (129), Expect = 2e-07
 Identities = 34/121 (28%), Positives = 57/121 (47%), Gaps = 32/121 (26%)
 Frame = -2

Query: 524 RVCGQLAVSRAFGDRNLKS----------------------------LLKSEPDVKVEDI 429
           R+CG +AVSRAFGD   K+                            ++ + PD+    +
Sbjct: 225 RICGDIAVSRAFGDIRFKTKKNDMLKKGVDEGRWSEKFVSRIEFKGDMVVATPDIFQVPL 284

Query: 428 DHTAELVVLASDGVWKVMNNREAV----DVVKKYKDPQTAAKQLIAEAVKRDSKDDISCV 261
               E ++LASDG+W  M + + V    D ++K+ + Q A + L   A+ R S+D+IS +
Sbjct: 285 TSDVEFIILASDGLWDYMKSSDVVSYVRDQLRKHGNVQLACESLAQVALDRRSQDNISII 344

Query: 260 V 258
           +
Sbjct: 345 I 345
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>PP2CB_MOUSE (P36993) Protein phosphatase 2C isoform beta (EC 3.1.3.16)|
           (PP2C-beta) (IA) (Protein phosphatase 1B)
          Length = 390

 Score = 53.9 bits (128), Expect = 3e-07
 Identities = 37/107 (34%), Positives = 53/107 (49%), Gaps = 13/107 (12%)
 Frame = -2

Query: 530 VPRVCGQLAVSRAFGDRNLK---------SLLKSEPDVKVEDIDHTAELVVLASDGVWKV 378
           + RV G LAVSRA GD + K          L+  EP+V         E VVLA DG+W V
Sbjct: 189 IQRVNGSLAVSRALGDYDYKCVDGKGPTEQLVSPEPEVYEIVRAEEDEFVVLACDGIWDV 248

Query: 377 MNNREAVDVVKK----YKDPQTAAKQLIAEAVKRDSKDDISCVVVRF 249
           M+N E  + VK       D +     ++   + + S+D++S V+V F
Sbjct: 249 MSNEELCEFVKSRLEVSDDLENVCNWVVDTCLHKGSRDNMSVVLVCF 295
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>PPM1F_HUMAN (P49593) Ca(2+)/calmodulin-dependent protein kinase phosphatase (EC|
           3.1.3.16) (CaM-kinase phosphatase) (CaMKPase) (Partner
           of PIX 2) (hFEM-2) (Protein phosphatase 1F)
          Length = 454

 Score = 53.5 bits (127), Expect = 4e-07
 Identities = 38/105 (36%), Positives = 59/105 (56%), Gaps = 5/105 (4%)
 Frame = -2

Query: 554 FVSNMPGDVPRVCGQLAVSRAFGDRNLKSLLKSEPDVKVEDIDHTAELVVLASDGVWKVM 375
           FVS+M  D  RV G LAVSRA GD   K  +  E D     +  + + ++LA DG + V+
Sbjct: 309 FVSHM--DCWRVNGTLAVSRAIGDVFQKPYVSGEADAASRALTGSEDYLLLACDGFFDVV 366

Query: 374 NNREAVDVVKKYKDPQ-----TAAKQLIAEAVKRDSKDDISCVVV 255
            ++E V +V+ +   Q       A++L+A A +R S D+I+ +VV
Sbjct: 367 PHQEVVGLVQSHLTRQQGSGLRVAEELVAAARERGSHDNITVMVV 411
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>PP2CB_BOVIN (O62830) Protein phosphatase 2C isoform beta (EC 3.1.3.16)|
           (PP2C-beta)
          Length = 387

 Score = 52.8 bits (125), Expect = 7e-07
 Identities = 35/107 (32%), Positives = 53/107 (49%), Gaps = 13/107 (12%)
 Frame = -2

Query: 530 VPRVCGQLAVSRAFGDRNLK---------SLLKSEPDVKVEDIDHTAELVVLASDGVWKV 378
           + RV G LAVSRA GD + K          L+  EP+V         E ++LA DG+W V
Sbjct: 189 IQRVNGSLAVSRALGDYDYKCVDGKGPTEQLVSPEPEVYEILRAEEDEFIILACDGIWDV 248

Query: 377 MNNREAVDVVKK----YKDPQTAAKQLIAEAVKRDSKDDISCVVVRF 249
           M+N E  + VK       D +     ++   + + S+D++S V+V F
Sbjct: 249 MSNEELCEFVKSRLEVSDDLENVCNWVVDTCLHKGSRDNMSIVLVCF 295
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>PP2CB_HUMAN (O75688) Protein phosphatase 2C isoform beta (EC 3.1.3.16)|
           (PP2C-beta)
          Length = 479

 Score = 52.8 bits (125), Expect = 7e-07
 Identities = 35/107 (32%), Positives = 53/107 (49%), Gaps = 13/107 (12%)
 Frame = -2

Query: 530 VPRVCGQLAVSRAFGDRNLK---------SLLKSEPDVKVEDIDHTAELVVLASDGVWKV 378
           + RV G LAVSRA GD + K          L+  EP+V         E ++LA DG+W V
Sbjct: 189 IQRVNGSLAVSRALGDYDYKCVDGKGPTEQLVSPEPEVYEILRAEEDEFIILACDGIWDV 248

Query: 377 MNNREAVDVVKK----YKDPQTAAKQLIAEAVKRDSKDDISCVVVRF 249
           M+N E  + VK       D +     ++   + + S+D++S V+V F
Sbjct: 249 MSNEELCEYVKSRLEVSDDLENVCNWVVDTCLHKGSRDNMSIVLVCF 295
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>PP2CB_RAT (P35815) Protein phosphatase 2C isoform beta (EC 3.1.3.16)|
           (PP2C-beta) (IA) (Protein phosphatase 1B)
          Length = 390

 Score = 51.6 bits (122), Expect = 1e-06
 Identities = 36/107 (33%), Positives = 52/107 (48%), Gaps = 13/107 (12%)
 Frame = -2

Query: 530 VPRVCGQLAVSRAFGDRNLK---------SLLKSEPDVKVEDIDHTAELVVLASDGVWKV 378
           + RV G LAVSRA GD + K          L+  EP+V         E VVLA DG+W V
Sbjct: 189 IQRVNGSLAVSRALGDYDYKCVDGKGPTEQLVSPEPEVYEILRAEEDEFVVLACDGIWDV 248

Query: 377 MNNREAVDVVKK----YKDPQTAAKQLIAEAVKRDSKDDISCVVVRF 249
           M+N E  + V        D +     ++   + + S+D++S V+V F
Sbjct: 249 MSNEELCEFVNSRLEVSDDLENVCNWVVDTCLHKGSRDNMSIVLVCF 295
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>PP2C4_SCHPO (O14156) Protein phosphatase 2C homolog 4 (EC 3.1.3.16) (PP2C-4)|
          Length = 383

 Score = 50.8 bits (120), Expect = 3e-06
 Identities = 32/89 (35%), Positives = 52/89 (58%), Gaps = 3/89 (3%)
 Frame = -2

Query: 509 LAVSRAFGDR-NLKSL-LKSEPDV-KVEDIDHTAELVVLASDGVWKVMNNREAVDVVKKY 339
           +A +R+FGD   LK L + +EP +  +  +      + L SDG+  V+++ E VD++K  
Sbjct: 267 VANTRSFGDGYKLKKLGVVAEPQLTSIHSLRDDWSFLTLLSDGITDVVSDDEVVDIIKLS 326

Query: 338 KDPQTAAKQLIAEAVKRDSKDDISCVVVR 252
           + PQ AA  +I  A    + DDI+C+VVR
Sbjct: 327 ESPQDAANNIIRYAQNVGAVDDITCLVVR 355
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>PP2CG_MOUSE (Q61074) Protein phosphatase 2C isoform gamma (EC 3.1.3.16)|
           (PP2C-gamma) (Protein phosphatase magnesium-dependent 1
           gamma) (Protein phosphatase 1C) (Fibroblast growth
           factor-inducible protein 13) (FIN13)
          Length = 542

 Score = 49.7 bits (117), Expect = 6e-06
 Identities = 32/118 (27%), Positives = 63/118 (53%), Gaps = 25/118 (21%)
 Frame = -2

Query: 524 RVCGQLAVSRAFGD------RNL---KSLLKSEPDVKVEDIDHTAELVVLASDGVWKVMN 372
           RV G L +SRA GD      +NL   + ++ + PD+KV  +    E +V+A DG+W VM+
Sbjct: 386 RVNGGLNLSRAIGDHFYKRNKNLPPQEQMISALPDIKVLTLTDDHEFMVIACDGIWNVMS 445

Query: 371 NREAVDVVK----------KYKDPQTAAKQLIAEAVKRDSK------DDISCVVVRFK 246
           ++E VD ++          + +   +  ++L+ + +  D+       D+++C+++ FK
Sbjct: 446 SQEVVDFIQSKISQRDENGELRLLSSIVEELLDQCLAPDTSGDGTGCDNMTCIIICFK 503
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>PP2CG_HUMAN (O15355) Protein phosphatase 2C isoform gamma (EC 3.1.3.16)|
           (PP2C-gamma) (Protein phosphatase magnesium-dependent 1
           gamma) (Protein phosphatase 1C)
          Length = 546

 Score = 49.7 bits (117), Expect = 6e-06
 Identities = 32/118 (27%), Positives = 63/118 (53%), Gaps = 25/118 (21%)
 Frame = -2

Query: 524 RVCGQLAVSRAFGD------RNL---KSLLKSEPDVKVEDIDHTAELVVLASDGVWKVMN 372
           RV G L +SRA GD      +NL   + ++ + PD+KV  +    E +V+A DG+W VM+
Sbjct: 389 RVNGGLNLSRAIGDHFYKRNKNLPPEEQMISALPDIKVLTLTDDHEFMVIACDGIWNVMS 448

Query: 371 NREAVDVVK----------KYKDPQTAAKQLIAEAVKRDSK------DDISCVVVRFK 246
           ++E VD ++          + +   +  ++L+ + +  D+       D+++C+++ FK
Sbjct: 449 SQEVVDFIQSKISQRDENGELRLLSSIVEELLDQCLAPDTSGDGTGCDNMTCIIICFK 506
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>PP2C1_CAEEL (P49595) Probable protein phosphatase 2C F42G9.1 (EC 3.1.3.16)|
           (PP2C)
          Length = 491

 Score = 48.9 bits (115), Expect = 1e-05
 Identities = 26/69 (37%), Positives = 39/69 (56%), Gaps = 9/69 (13%)
 Frame = -2

Query: 524 RVCGQLAVSRAFGDRNLKS---------LLKSEPDVKVEDIDHTAELVVLASDGVWKVMN 372
           RV G L +SRAFGD   K          ++ + PDVK+E +    E +V+A DG+W  M 
Sbjct: 376 RVNGGLNLSRAFGDHAYKKNQELGLKEQMITALPDVKIEALTPEDEFIVVACDGIWNSME 435

Query: 371 NREAVDVVK 345
           +++ VD V+
Sbjct: 436 SQQVVDFVR 444
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>PP2CG_BOVIN (P79126) Protein phosphatase 2C isoform gamma (EC 3.1.3.16)|
           (PP2C-gamma) (Protein phosphatase magnesium-dependent 1
           gamma) (Protein phosphatase 1B) (Magnesium-dependent
           calcium inhibitable phosphatase) (MCPP)
          Length = 543

 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 31/118 (26%), Positives = 62/118 (52%), Gaps = 25/118 (21%)
 Frame = -2

Query: 524 RVCGQLAVSRAFGD------RNL---KSLLKSEPDVKVEDIDHTAELVVLASDGVWKVMN 372
           RV G L +SRA GD      +NL   + ++ + PD+KV  +    E +V+A DG+W VM+
Sbjct: 387 RVNGGLNLSRAIGDHFYKRNKNLPPEEQMISALPDIKVLTLTDDHEFMVIACDGIWNVMS 446

Query: 371 NREAVDVVK----------KYKDPQTAAKQLIAEAVKRDSK------DDISCVVVRFK 246
           ++E +D ++          + +   +  + L+ + +  D+       D+++C+++ FK
Sbjct: 447 SQEVIDFIQSKISQRDENGELRLLSSIVEYLLDQCLAPDTSGDGTGCDNMTCIIICFK 504
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>PP2C3_SCHPO (Q09173) Protein phosphatase 2C homolog 3 (EC 3.1.3.16) (PP2C-3)|
          Length = 414

 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 26/72 (36%), Positives = 40/72 (55%), Gaps = 8/72 (11%)
 Frame = -2

Query: 533 DVPRVCGQLAVSRAFGDRNLKS--------LLKSEPDVKVEDIDHTAELVVLASDGVWKV 378
           D  RV G LA+SRA GD   K+        ++ + PDV V +I    E VVLA DG+W  
Sbjct: 176 DFGRVNGNLALSRAIGDFEFKNSNLEPEKQIVTALPDVVVHEITDDDEFVVLACDGIWDC 235

Query: 377 MNNREAVDVVKK 342
             +++ ++ V++
Sbjct: 236 KTSQQVIEFVRR 247
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>PP2C2_SCHPO (Q09172) Protein phosphatase 2C homolog 2 (EC 3.1.3.16) (PP2C-2)|
          Length = 370

 Score = 47.4 bits (111), Expect = 3e-05
 Identities = 25/73 (34%), Positives = 41/73 (56%), Gaps = 9/73 (12%)
 Frame = -2

Query: 533 DVPRVCGQLAVSRAFGDRNLKS---------LLKSEPDVKVEDIDHTAELVVLASDGVWK 381
           D  RV G LA+SRA GD   K          ++ + PDV + +ID   E ++LA DG+W 
Sbjct: 178 DFGRVNGSLALSRAIGDFEYKKDSSLPPEKQIVTAFPDVVIHNIDPDDEFLILACDGIWD 237

Query: 380 VMNNREAVDVVKK 342
             ++++ V+ V++
Sbjct: 238 CKSSQQVVEFVRR 250
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>PPM1F_MOUSE (Q8CGA0) Ca(2+)/calmodulin-dependent protein kinase phosphatase (EC|
           3.1.3.16) (CaM-kinase phosphatase) (CaMKPase) (Protein
           phosphatase 1F)
          Length = 452

 Score = 47.4 bits (111), Expect = 3e-05
 Identities = 36/105 (34%), Positives = 55/105 (52%), Gaps = 5/105 (4%)
 Frame = -2

Query: 554 FVSNMPGDVPRVCGQLAVSRAFGDRNLKSLLKSEPDVKVEDIDHTAELVVLASDGVWKVM 375
           FVS M  D  RV G LAVSRA GD   K  +  E D    ++  + + ++LA DG + V+
Sbjct: 306 FVSLM--DCWRVNGTLAVSRAIGDVFQKPYVSGEADAASRELTGSEDYLLLACDGFFDVV 363

Query: 374 NNREAVDVV-----KKYKDPQTAAKQLIAEAVKRDSKDDISCVVV 255
            + E   +V     +   +    A++L+A A  R S D+I+ +VV
Sbjct: 364 PHHEVTGLVHGHLLRHKGNGMRIAEELVAVARDRGSHDNITVMVV 408
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>PP2CE_MOUSE (Q8BU27) Protein phosphatase 2C isoform eta (EC 3.1.3.16)|
           (PP2C-eta) (PP2CE) (Protein phosphatase 1M)
          Length = 406

 Score = 46.2 bits (108), Expect = 6e-05
 Identities = 40/125 (32%), Positives = 57/125 (45%), Gaps = 31/125 (24%)
 Frame = -2

Query: 536 GDVPRVCGQLAVSRAFGDRNLKSL---------LKSEPDVKVEDIDHTA----ELVVLAS 396
           G   R+ G LAVSR  GD  L+ L         L S P V V D+   A    ++VV+A+
Sbjct: 270 GRQARLLGTLAVSRGLGDHQLRVLDTDIQLKPFLLSIPQVTVLDVHQLAVQEEDVVVMAT 329

Query: 395 DGVWKVMNNREAVDVVKKY------KDP---QTAAKQLIAEAVKRD---------SKDDI 270
           DG+W V++N +   +V+ +       DP      AK LI     +D         S DD+
Sbjct: 330 DGLWDVLSNEQVALLVRSFLTGNQKDDPHRFSELAKMLIHNTQGKDNGATGEGQVSYDDV 389

Query: 269 SCVVV 255
           S  V+
Sbjct: 390 SVFVI 394
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>PP2CE_HUMAN (Q96MI6) Protein phosphatase 2C isoform eta (EC 3.1.3.16)|
           (PP2C-eta) (PP2CE) (Protein phosphatase 1M)
          Length = 270

 Score = 45.8 bits (107), Expect = 8e-05
 Identities = 28/79 (35%), Positives = 42/79 (53%), Gaps = 13/79 (16%)
 Frame = -2

Query: 536 GDVPRVCGQLAVSRAFGDRNLKSL---------LKSEPDVKVEDIDHTA----ELVVLAS 396
           G   R+ G LAVSR  GD  L+ L         L S P V V D+D       ++VV+A+
Sbjct: 163 GRQARLLGTLAVSRGLGDHQLRVLDTNIQLKPFLLSVPQVTVLDVDQLELQEDDVVVMAT 222

Query: 395 DGVWKVMNNREAVDVVKKY 339
           DG+W V++N +   +V+ +
Sbjct: 223 DGLWDVLSNEQVAWLVRSF 241
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>PPM1F_RAT (Q9WVR7) Ca(2+)/calmodulin-dependent protein kinase phosphatase (EC|
           3.1.3.16) (CaM-kinase phosphatase) (CaMKPase) (Partner
           of PIX 2) (Protein phosphatase 1F)
          Length = 450

 Score = 45.8 bits (107), Expect = 8e-05
 Identities = 36/105 (34%), Positives = 54/105 (51%), Gaps = 5/105 (4%)
 Frame = -2

Query: 554 FVSNMPGDVPRVCGQLAVSRAFGDRNLKSLLKSEPDVKVEDIDHTAELVVLASDGVWKVM 375
           FVS M  D  RV G LAVSRA GD   K  +  E D    ++    + ++LA DG + V+
Sbjct: 305 FVSLM--DCWRVNGTLAVSRAIGDVFQKPYVSGEADAASRELTGLEDYLLLACDGFFDVV 362

Query: 374 NNREAVDVV-----KKYKDPQTAAKQLIAEAVKRDSKDDISCVVV 255
            + E   +V     ++       A++L+A A  R S D+I+ +VV
Sbjct: 363 PHHEIPGLVHGHLLRQKGSGMHVAEELVAVARDRGSHDNITVMVV 407
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>PP2C2_YEAST (P39966) Protein phosphatase 2C homolog 2 (EC 3.1.3.16) (PP2C-2)|
          Length = 464

 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 25/72 (34%), Positives = 40/72 (55%), Gaps = 10/72 (13%)
 Frame = -2

Query: 533 DVPRVCGQLAVSRAFGDRNLKS---------LLKSEPDVKVEDIDHTA-ELVVLASDGVW 384
           ++ RV G LA+SRA GD   KS         ++   PD+    +D+   E V+LA DG+W
Sbjct: 178 EMDRVNGNLALSRAIGDFEFKSNPKLGPEEQIVTCVPDILEHSLDYDRDEFVILACDGIW 237

Query: 383 KVMNNREAVDVV 348
             + +++ VD+V
Sbjct: 238 DCLTSQDCVDLV 249
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>FEM2_CAEEL (P49594) Ca(2+)/calmodulin-dependent protein kinase phosphatase (EC|
           3.1.3.16) (CaM-kinase phosphatase) (CaMKPase)
           (Sex-determining protein fem-2) (Feminization of XX and
           XO animals protein 2)
          Length = 449

 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 27/95 (28%), Positives = 52/95 (54%), Gaps = 6/95 (6%)
 Frame = -2

Query: 524 RVCGQLAVSRAFGDRNLKSLLKSEPDVKVEDIDHTAELVVLASDGVWKVMNNREAVDVVK 345
           RV G L ++RA GD   + ++ +EP+     I+ +  LV+LA DG+  V N R+   +V+
Sbjct: 327 RVNGVLNLTRALGDVPGRPMISNEPETCQVPIESSDYLVLLACDGISDVFNERDLYQLVE 386

Query: 344 KY------KDPQTAAKQLIAEAVKRDSKDDISCVV 258
            +      +D    ++ +  +A++  S D++S V+
Sbjct: 387 AFANDYPVEDYAELSRFICTKAIEAGSADNVSVVI 421
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>PP2C3_YEAST (P34221) Protein phosphatase 2C homolog 3 (EC 3.1.3.16) (PP2C-3)|
          Length = 468

 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 25/72 (34%), Positives = 41/72 (56%), Gaps = 10/72 (13%)
 Frame = -2

Query: 533 DVPRVCGQLAVSRAFGDRNLKS---------LLKSEPDVKVEDIDHTA-ELVVLASDGVW 384
           ++ RV G LA+SRA GD   KS         ++   PD+   ++++   E V+LA DG+W
Sbjct: 178 EMDRVNGNLALSRAIGDFEFKSNTKLGPHEQVVTCVPDIICHNLNYDEDEFVILACDGIW 237

Query: 383 KVMNNREAVDVV 348
             + ++E VD+V
Sbjct: 238 DCLTSQECVDLV 249
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>CYAA_USTMA (P49606) Adenylate cyclase (EC 4.6.1.1) (ATP pyrophosphate-lyase)|
            (Adenylyl cyclase)
          Length = 2493

 Score = 43.5 bits (101), Expect = 4e-04
 Identities = 24/86 (27%), Positives = 50/86 (58%), Gaps = 1/86 (1%)
 Frame = -2

Query: 509  LAVSRAFGDRNLKSLLKSEPDVKVEDIDHTAELVVLASDGVWKVMNNREAVDVVKKYK-D 333
            L VSR+FG  +L  ++ + P V    +  + E V++A+  +W+ ++ + AVD+ +  + D
Sbjct: 1913 LDVSRSFGYFHLFPIVNAAPAVTTVQLTDSDEFVIIANRTLWQYVSYQTAVDIARTQRND 1972

Query: 332  PQTAAKQLIAEAVKRDSKDDISCVVV 255
            P  AA++L   A+   +++ I  +V+
Sbjct: 1973 PMIAAQKLRDFAISYGAEESIMVMVI 1998
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>PHLPL_HUMAN (Q6ZVD8) PH domain leucine-rich repeat protein phosphatase-like (EC|
            3.1.3.16)
          Length = 1323

 Score = 42.4 bits (98), Expect = 9e-04
 Identities = 24/90 (26%), Positives = 45/90 (50%)
 Frame = -2

Query: 524  RVCGQLAVSRAFGDRNLKSLLKSEPDVKVEDIDHTAELVVLASDGVWKVMNNREAVDVVK 345
            +V G    +R  G   L   +  +P +    +    EL++L +  +W+ ++  EAV+ V+
Sbjct: 942  KVNGVTCCTRMLGCTYLYPWILPKPHISSTPLTIQDELLILGNKALWEHLSYTEAVNAVR 1001

Query: 344  KYKDPQTAAKQLIAEAVKRDSKDDISCVVV 255
              +DP  AAK+L   A     +D++  +VV
Sbjct: 1002 HVQDPLAAAKKLCTLAQSYGCQDNVGAMVV 1031
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>PHLPL_MOUSE (Q8BXA7) PH domain leucine-rich repeat protein phosphatase-like (EC|
            3.1.3.16)
          Length = 1320

 Score = 41.6 bits (96), Expect = 0.002
 Identities = 24/90 (26%), Positives = 45/90 (50%)
 Frame = -2

Query: 524  RVCGQLAVSRAFGDRNLKSLLKSEPDVKVEDIDHTAELVVLASDGVWKVMNNREAVDVVK 345
            +V G    +R  G   L   +  +P +    +    EL++L +  +W+ ++  EAV+ V+
Sbjct: 939  KVNGVTCCTRLLGCTYLYPWILPKPHIASTPLTIQDELLILGNKALWEHLSYLEAVNAVR 998

Query: 344  KYKDPQTAAKQLIAEAVKRDSKDDISCVVV 255
              +DP  AAK+L   A     +D++  +VV
Sbjct: 999  HVQDPLAAAKKLCTLAQSYGCQDNVGAMVV 1028
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>PHLPP_RAT (Q9WTR8) PH domain leucine-rich repeat protein phosphatase (EC|
            3.1.3.16) (Pleckstrin homology domain-containing family E
            protein 1) (Suprachiasmatic nucleus circadian oscillatory
            protein)
          Length = 1696

 Score = 40.8 bits (94), Expect = 0.003
 Identities = 28/94 (29%), Positives = 42/94 (44%)
 Frame = -2

Query: 524  RVCGQLAVSRAFGDRNLKSLLKSEPDVKVEDIDHTAELVVLASDGVWKVMNNREAVDVVK 345
            +V G    +R  G   L   +   P V+   +    E  +L S G+W  ++  EAV+ V+
Sbjct: 1294 KVNGVTESTRILGYTFLHPSVVPRPHVQSVLLTPQDEFFILGSKGLWDSLSIEEAVEAVR 1353

Query: 344  KYKDPQTAAKQLIAEAVKRDSKDDISCVVVRFKM 243
               D   AAK+L   A      D IS VVV+  +
Sbjct: 1354 NVPDALAAAKKLCTLAQSYGCHDSISAVVVQLSV 1387
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>PHLPP_HUMAN (O60346) PH domain leucine-rich repeat-containing protein phosphatase|
            (EC 3.1.3.16) (PH domain leucine-rich repeat protein
            phosphatase) (Pleckstrin homology domain-containing
            family E protein 1) (Suprachiasmatic nucleus circadian
            oscillatory
          Length = 1717

 Score = 40.8 bits (94), Expect = 0.003
 Identities = 28/94 (29%), Positives = 42/94 (44%)
 Frame = -2

Query: 524  RVCGQLAVSRAFGDRNLKSLLKSEPDVKVEDIDHTAELVVLASDGVWKVMNNREAVDVVK 345
            +V G    +R  G   L   +   P V+   +    E  +L S G+W  ++  EAV+ V+
Sbjct: 1331 KVNGVTESTRILGYTFLHPSVVPRPHVQSVLLTPQDEFFILGSKGLWDSLSVEEAVEAVR 1390

Query: 344  KYKDPQTAAKQLIAEAVKRDSKDDISCVVVRFKM 243
               D   AAK+L   A      D IS VVV+  +
Sbjct: 1391 NVPDALAAAKKLCTLAQSYGCHDSISAVVVQLSV 1424
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>PP2C4_YEAST (P38089) Protein phosphatase 2C homolog 4 (EC 3.1.3.16) (PP2C-4)|
          Length = 393

 Score = 40.4 bits (93), Expect = 0.003
 Identities = 27/88 (30%), Positives = 40/88 (45%), Gaps = 28/88 (31%)
 Frame = -2

Query: 524 RVCGQLAVSRAFGDRNLK---------------------------SLLKSEPDVKVEDID 426
           RV G LA+SRAF D   K                           + +  EPDV +  ID
Sbjct: 239 RVGGVLALSRAFSDFQFKRGVTYPHRRTKLTNITQNLTYGTPPQEAQVTVEPDVLMHKID 298

Query: 425 HTA-ELVVLASDGVWKVMNNREAVDVVK 345
           ++  E +VLA DG+W + NN++ +  +K
Sbjct: 299 YSKDEFLVLACDGIWDIYNNKQLIHFIK 326
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>CYAA_PODAN (Q01513) Adenylate cyclase (EC 4.6.1.1) (ATP pyrophosphate-lyase)|
            (Adenylyl cyclase)
          Length = 2145

 Score = 40.0 bits (92), Expect = 0.004
 Identities = 23/70 (32%), Positives = 41/70 (58%), Gaps = 3/70 (4%)
 Frame = -2

Query: 509  LAVSRAFGDRNLKSLLKSEPDVKVEDIDHTAELVVLASDGVWKVMNNREAVDV---VKKY 339
            L VSRAFG  +L   ++S P+++   I    E++++A+  VW+ +     VDV   V++ 
Sbjct: 1620 LEVSRAFGYLDLMPAVQSAPNIEKHTIGEHDEMILIATREVWEYLPKDVLVDVTRSVRQD 1679

Query: 338  KDPQTAAKQL 309
             DP  AA+++
Sbjct: 1680 PDPMRAAQKV 1689
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>PHLPP_MOUSE (Q8CHE4) PH domain leucine-rich repeat-containing protein phosphatase|
            (EC 3.1.3.16) (PH domain leucine-rich repeat protein
            phosphatase) (Pleckstrin homology domain-containing
            family E protein 1) (Suprachiasmatic nucleus circadian
            oscillatory
          Length = 1687

 Score = 40.0 bits (92), Expect = 0.004
 Identities = 28/94 (29%), Positives = 42/94 (44%)
 Frame = -2

Query: 524  RVCGQLAVSRAFGDRNLKSLLKSEPDVKVEDIDHTAELVVLASDGVWKVMNNREAVDVVK 345
            +V G    +R  G   L   +   P V+   +    E  +L S G+W  ++  EAV+ V+
Sbjct: 1287 KVNGVTESTRILGYTFLHPSVVPRPHVQSVLLTPQDEFFILGSKGLWDSLSIDEAVEAVR 1346

Query: 344  KYKDPQTAAKQLIAEAVKRDSKDDISCVVVRFKM 243
               D   AAK+L   A      D IS VVV+  +
Sbjct: 1347 NVPDALAAAKKLCTLAQSYGCHDSISAVVVQLSV 1380
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>CYAA_NEUCR (Q01631) Adenylate cyclase (EC 4.6.1.1) (ATP pyrophosphate-lyase)|
            (Adenylyl cyclase)
          Length = 2300

 Score = 39.7 bits (91), Expect = 0.006
 Identities = 22/70 (31%), Positives = 36/70 (51%)
 Frame = -2

Query: 509  LAVSRAFGDRNLKSLLKSEPDVKVEDIDHTAELVVLASDGVWKVMNNREAVDVVKKYKDP 330
            L VSRAFG   L   +++ PD+    ID   E V++AS  +W+ +     VDV ++ +  
Sbjct: 1741 LNVSRAFGYTELLPAVQAAPDITEHTIDDKDETVLIASKELWEHLRPELIVDVARECRSD 1800

Query: 329  QTAAKQLIAE 300
               A Q + +
Sbjct: 1801 LMKASQKLRD 1810
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>CYAA_SACKL (P23466) Adenylate cyclase (EC 4.6.1.1) (ATP pyrophosphate-lyase)|
            (Adenylyl cyclase)
          Length = 1839

 Score = 39.7 bits (91), Expect = 0.006
 Identities = 29/131 (22%), Positives = 61/131 (46%), Gaps = 1/131 (0%)
 Frame = -2

Query: 515  GQLAVSRAFGDRNLKSLLKSEPDVKVEDIDHTAELVVLASDGVWKVMNNREAVDVVKKYK 336
            G   VSRA G  +L   + + PD+    + ++ E++++A+  +W+ ++     D+ ++ K
Sbjct: 1350 GVSEVSRAVGFFDLLPHIHASPDISETVLSYSDEMLIIATHKLWEYLDYETVCDISRENK 1409

Query: 335  -DPQTAAKQLIAEAVKRDSKDDISCVVVRFKM*XXCR*LVKNCHREQKEL*QQNIACLTR 159
              P +AA+++   A+     D+I+ +                C    K + QQ+   L R
Sbjct: 1410 SQPMSAAEKMKDYAISYGCSDNITIL----------------CVSLDKSVNQQSQFTLNR 1453

Query: 158  IVVMQKNNTLE 126
              ++ + NT E
Sbjct: 1454 EDLISRKNTFE 1464
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>PP2CD_MOUSE (Q9QZ67) Protein phosphatase 2C isoform delta (EC 3.1.3.16)|
           (PP2C-delta) (p53-induced protein phosphatase 1)
           (Protein phosphatase magnesium-dependent 1 delta)
          Length = 598

 Score = 39.3 bits (90), Expect = 0.008
 Identities = 28/89 (31%), Positives = 47/89 (52%), Gaps = 15/89 (16%)
 Frame = -2

Query: 509 LAVSRAFGDR------NLKSLLKSEPDVKVEDID-HTAELVVLASDGVWKVMNNREAVDV 351
           LAV+RA GD       + K ++  EPD  V  +D    + ++L SDG+W ++  ++A+ +
Sbjct: 262 LAVARALGDLWSYDFFSGKFVVSPEPDTSVHTLDPRKHKYIILGSDGLWNMVPPQDAISM 321

Query: 350 V-----KKY---KDPQTAAKQLIAEAVKR 288
                 KKY   +  Q+ AK L+  A+ R
Sbjct: 322 CQDQEEKKYLMGEQGQSCAKMLVNRALGR 350
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>PP2C_PARTE (P49444) Protein phosphatase 2C (EC 3.1.3.16) (PP2C)|
          Length = 300

 Score = 38.1 bits (87), Expect = 0.017
 Identities = 23/87 (26%), Positives = 45/87 (51%), Gaps = 9/87 (10%)
 Frame = -2

Query: 524 RVCGQLAVSRAFGD---------RNLKSLLKSEPDVKVEDIDHTAELVVLASDGVWKVMN 372
           RV G L +SRA GD         R+ + L+ + PDVK  ++    + +++  DGV++ +N
Sbjct: 185 RVNGNLNLSRALGDLEYKRDNKLRSNEQLIIALPDVKKTELTPQDKFILMGCDGVFETLN 244

Query: 371 NREAVDVVKKYKDPQTAAKQLIAEAVK 291
           ++E +  V          ++L+ +A +
Sbjct: 245 HQELLKQVNSTIGQAQVTEELLKKAAE 271
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>CYAA_YEAST (P08678) Adenylate cyclase (EC 4.6.1.1) (ATP pyrophosphate-lyase)|
            (Adenylyl cyclase)
          Length = 2026

 Score = 37.7 bits (86), Expect = 0.022
 Identities = 32/131 (24%), Positives = 60/131 (45%), Gaps = 1/131 (0%)
 Frame = -2

Query: 515  GQLAVSRAFGDRNLKSLLKSEPDVKVEDIDHTAELVVLASDGVWKVMNNREAVDVVKKYK 336
            G + VSRA G  +L   + + PD+ V  +    E++++A+  +W+ M+     D+ ++  
Sbjct: 1535 GVVDVSRAVGFFDLLPHIHASPDISVVTLTKADEMLIVATHKLWEYMDVDTVCDIARENS 1594

Query: 335  -DPQTAAKQLIAEAVKRDSKDDISCVVVRFKM*XXCR*LVKNCHREQKEL*QQNIACLTR 159
             DP  AA +L   A+     ++I+ +         C  L +N         QQN   L +
Sbjct: 1595 TDPLRAAAELKDHAMAYGCTENITIL---------CLALYENIQ-------QQNRFTLNK 1638

Query: 158  IVVMQKNNTLE 126
              +M + +T E
Sbjct: 1639 NSLMTRRSTFE 1649
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>PP2CD_HUMAN (O15297) Protein phosphatase 2C isoform delta (EC 3.1.3.16)|
           (PP2C-delta) (p53-induced protein phosphatase 1)
           (Protein phosphatase magnesium-dependent 1 delta)
          Length = 605

 Score = 37.4 bits (85), Expect = 0.029
 Identities = 27/89 (30%), Positives = 47/89 (52%), Gaps = 15/89 (16%)
 Frame = -2

Query: 509 LAVSRAFGDR------NLKSLLKSEPDVKVEDID-HTAELVVLASDGVWKVMNNREAVDV 351
           LAV+RA GD       + + ++  EPD  V  +D    + ++L SDG+W ++  ++A+ +
Sbjct: 269 LAVARALGDLWSYDFFSGEFVVSPEPDTSVHTLDPQKHKYIILGSDGLWNMIPPQDAISM 328

Query: 350 V-----KKY---KDPQTAAKQLIAEAVKR 288
                 KKY   +  Q+ AK L+  A+ R
Sbjct: 329 CQDQEEKKYLMGEHGQSCAKMLVNRALGR 357
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>CYAA_SCHPO (P14605) Adenylate cyclase (EC 4.6.1.1) (ATP pyrophosphate-lyase)|
            (Adenylyl cyclase)
          Length = 1692

 Score = 35.8 bits (81), Expect = 0.084
 Identities = 21/83 (25%), Positives = 44/83 (53%), Gaps = 1/83 (1%)
 Frame = -2

Query: 500  SRAFGDRNLKSLLKSEPDVKVEDIDHTAELVVLASDGVWKVMNNREAVDVVKKYK-DPQT 324
            +RA G  +    +++ P V V+ +    E ++LA+   W V++ R  +DVV+  +  P  
Sbjct: 1191 TRAIGRLSQFPGVQAVPYVNVQYLSELNEFIILANQEFWSVLSKRTVIDVVRANRHSPLL 1250

Query: 323  AAKQLIAEAVKRDSKDDISCVVV 255
            A+ +L   A+   ++ ++  V+V
Sbjct: 1251 ASTKLRDYAIAYGAEKNVLVVIV 1273
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>PHLPP_DROME (Q9VJ07) Protein phosphatase PHLPP-like protein (EC 3.1.3.16)|
           (dPHLPP)
          Length = 954

 Score = 35.4 bits (80), Expect = 0.11
 Identities = 22/78 (28%), Positives = 42/78 (53%), Gaps = 2/78 (2%)
 Frame = -2

Query: 473 KSLLKSEPDVKVEDI--DHTAELVVLASDGVWKVMNNREAVDVVKKYKDPQTAAKQLIAE 300
           K  + S PD  V ++   +  E +V+ +  +W VM+   A   ++K ++   AAK+L+  
Sbjct: 579 KDQIHSMPDPHVLELILSNDDEYLVVGNAQLWSVMDIDRAAREIRKEENSLLAAKRLVDI 638

Query: 299 AVKRDSKDDISCVVVRFK 246
           A    + + +S +VVRF+
Sbjct: 639 AQSFAAAESLSVIVVRFR 656
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>KAPP_ARATH (P46014) Kinase-associated protein phosphatase (EC 3.1.3.16)|
          Length = 581

 Score = 35.0 bits (79), Expect = 0.14
 Identities = 30/99 (30%), Positives = 52/99 (52%), Gaps = 14/99 (14%)
 Frame = -2

Query: 503 VSRAFGDRNLK---SLLKSEPDVKVE-DIDHTAELV--VLASDGVWKVMNNREAVDVVKK 342
           ++R  GD+  K   S   +EP +     ID +++ V  VLASDG+W V++ ++AV +V +
Sbjct: 479 LARMLGDKFPKQQDSRFSAEPYISEPLRIDQSSKDVFAVLASDGLWDVVSPKKAVQLVLQ 538

Query: 341 YKDPQTA--------AKQLIAEAVKRDSKDDISCVVVRF 249
            +D +          A  L+ EA    +KD+ S + + F
Sbjct: 539 MRDKERGRESSAEKIANGLLNEARAMRTKDNTSIIYLDF 577
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>PDP1_HUMAN (Q9P0J1) [Pyruvate dehydrogenase [lipoamide]]-phosphatase 1,|
           mitochondrial precursor (EC 3.1.3.43) (PDP 1) (Pyruvate
           dehydrogenase phosphatase, catalytic subunit 1) (PDPC 1)
           (Protein phosphatase 2C)
          Length = 537

 Score = 34.3 bits (77), Expect = 0.24
 Identities = 14/42 (33%), Positives = 27/42 (64%)
 Frame = -2

Query: 464 LKSEPDVKVEDIDHTAELVVLASDGVWKVMNNREAVDVVKKY 339
           L +EP+V    +    + +VLA+DG+W+ M+ ++ V +V +Y
Sbjct: 395 LTAEPEVTYHRLRPQDKFLVLATDGLWETMHRQDVVRIVGEY 436
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>PDP1_RAT (O88483) [Pyruvate dehydrogenase [lipoamide]]-phosphatase 1,|
           mitochondrial precursor (EC 3.1.3.43) (PDP 1) (Pyruvate
           dehydrogenase phosphatase, catalytic subunit 1) (PDPC 1)
           (Protein phosphatase 2C)
          Length = 538

 Score = 34.3 bits (77), Expect = 0.24
 Identities = 14/42 (33%), Positives = 27/42 (64%)
 Frame = -2

Query: 464 LKSEPDVKVEDIDHTAELVVLASDGVWKVMNNREAVDVVKKY 339
           L +EP+V    +    + +VLA+DG+W+ M+ ++ V +V +Y
Sbjct: 395 LTAEPEVTYHRLRPQDKFLVLATDGLWETMHRQDVVRIVGEY 436
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>PDP1_MOUSE (Q3UV70) [Pyruvate dehydrogenase [lipoamide]]-phosphatase 1,|
           mitochondrial precursor (EC 3.1.3.43) (PDP 1) (Pyruvate
           dehydrogenase phosphatase, catalytic subunit 1) (PDPC 1)
           (Protein phosphatase 2C)
          Length = 538

 Score = 34.3 bits (77), Expect = 0.24
 Identities = 14/42 (33%), Positives = 27/42 (64%)
 Frame = -2

Query: 464 LKSEPDVKVEDIDHTAELVVLASDGVWKVMNNREAVDVVKKY 339
           L +EP+V    +    + +VLA+DG+W+ M+ ++ V +V +Y
Sbjct: 395 LTAEPEVTYHRLRPQDKFLVLATDGLWETMHRQDVVRIVGEY 436
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>PDP1_BOVIN (P35816) [Pyruvate dehydrogenase [lipoamide]]-phosphatase 1,|
           mitochondrial precursor (EC 3.1.3.43) (PDP 1) (Pyruvate
           dehydrogenase phosphatase, catalytic subunit 1) (PDPC 1)
           (Protein phosphatase 2C)
          Length = 538

 Score = 34.3 bits (77), Expect = 0.24
 Identities = 14/42 (33%), Positives = 27/42 (64%)
 Frame = -2

Query: 464 LKSEPDVKVEDIDHTAELVVLASDGVWKVMNNREAVDVVKKY 339
           L +EP+V    +    + +VLA+DG+W+ M+ ++ V +V +Y
Sbjct: 395 LTAEPEVTYHRLRPQDKFLVLATDGLWETMHRQDVVRIVGEY 436
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>Y2780_ENTFA (Q830K2) UPF0133 protein EF2780|
          Length = 104

 Score = 33.9 bits (76), Expect = 0.32
 Identities = 19/52 (36%), Positives = 29/52 (55%), Gaps = 1/52 (1%)
 Frame = -2

Query: 512 QLAVSRAFGDRNLKSLLKSEPDVKVEDIDHTAELVVLA-SDGVWKVMNNREA 360
           QL  +   GDR +K L+  E  V  ED+D   +LV++A +D + K+    EA
Sbjct: 41  QLVTATFTGDRTMKDLIIKEDVVDPEDVDMLQDLVIMAVNDALVKIEKETEA 92
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>PDP2_HUMAN (Q9P2J9) [Pyruvate dehydrogenase [lipoamide]]-phosphatase 2,|
           mitochondrial precursor (EC 3.1.3.43) (PDP 2) (Pyruvate
           dehydrogenase phosphatase, catalytic subunit 2) (PDPC 2)
          Length = 529

 Score = 32.7 bits (73), Expect = 0.71
 Identities = 14/39 (35%), Positives = 25/39 (64%)
 Frame = -2

Query: 464 LKSEPDVKVEDIDHTAELVVLASDGVWKVMNNREAVDVV 348
           L +EP+V    +    + +VLASDG+W +++N + V +V
Sbjct: 389 LTAEPEVTYHRLRPQDKFLVLASDGLWDMLSNEDVVRLV 427
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>PP2C5_YEAST (Q12511) Protein phosphatase 2C homolog 5 (EC 3.1.3.16) (PP2C-5)|
          Length = 572

 Score = 32.3 bits (72), Expect = 0.93
 Identities = 26/116 (22%), Positives = 43/116 (37%), Gaps = 30/116 (25%)
 Frame = -2

Query: 524 RVCGQLAVSRAFGDRNLK------------------------------SLLKSEPDVKVE 435
           R+ G L  SRAFGD   K                                + +EP +   
Sbjct: 351 RILGSLQPSRAFGDYRYKIKEVDGKPLSDLPEVAKLYFRREPRDFKTPPYVTAEPVITSA 410

Query: 434 DIDHTAELVVLASDGVWKVMNNREAVDVVKKYKDPQTAAKQLIAEAVKRDSKDDIS 267
            I    + +V+ SDG+++++ N E   +V ++ D       + AE  K     D+S
Sbjct: 411 KIGENTKFMVMGSDGLFELLTNEEIASLVIRWMDKNMNLAPVKAEPGKLPKVIDVS 466
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>PDP2_RAT (O88484) [Pyruvate dehydrogenase [lipoamide]]-phosphatase 2,|
           mitochondrial precursor (EC 3.1.3.43) (PDP 2) (Pyruvate
           dehydrogenase phosphatase, catalytic subunit 2) (PDPC 2)
          Length = 530

 Score = 31.2 bits (69), Expect = 2.1
 Identities = 13/39 (33%), Positives = 25/39 (64%)
 Frame = -2

Query: 464 LKSEPDVKVEDIDHTAELVVLASDGVWKVMNNREAVDVV 348
           L ++P+V    +    + +VLASDG+W +++N + V +V
Sbjct: 390 LTAKPEVTYHRLRPQDKFLVLASDGLWDMLDNEDVVRLV 428
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>CARD_PECCC (Q9XB58) Carbapenem antibiotics biosynthesis protein carD|
          Length = 376

 Score = 30.8 bits (68), Expect = 2.7
 Identities = 21/61 (34%), Positives = 27/61 (44%)
 Frame = +1

Query: 175 MFCCYNSFCSR*QFFTSYLHXIYILNRTTTHDISSLLSLFTASAINCLAAVCGSLYFFTT 354
           ++  YN + SR  FF       Y    T TH ++  LSLFT     CLA   G L+    
Sbjct: 5   LYAIYNRYTSRTLFFK------YCATATLTHRLTRRLSLFTLK--KCLARPQGRLFSLVN 56

Query: 355 S 357
           S
Sbjct: 57  S 57
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>GYRA_BUCAP (Q8K9W2) DNA gyrase subunit A (EC 5.99.1.3)|
          Length = 825

 Score = 30.4 bits (67), Expect = 3.5
 Identities = 19/86 (22%), Positives = 39/86 (45%), Gaps = 4/86 (4%)
 Frame = -2

Query: 509 LAVSRAFGDRNLKSLLKSEPDVKVEDIDHTAELVVLASDGVWKVMNNREAVDVVKKYKDP 330
           +++   FGD+    + ++ PD+ +ED+ +  ++VV  S   +         +  K+    
Sbjct: 489 VSIKNNFGDQRRTEITENNPDISIEDLINQEDVVVTLSHSGYVKYQPLSDYNAQKRGGKG 548

Query: 329 QTAAK----QLIAEAVKRDSKDDISC 264
           ++AAK      I   V  ++ D I C
Sbjct: 549 KSAAKIKEEDFIESLVVTNTHDTILC 574
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>G6PI_PSEFL (Q848I4) Glucose-6-phosphate isomerase (EC 5.3.1.9) (GPI)|
           (Phosphoglucose isomerase) (PGI) (Phosphohexose
           isomerase) (PHI)
          Length = 554

 Score = 30.0 bits (66), Expect = 4.6
 Identities = 20/81 (24%), Positives = 38/81 (46%)
 Frame = -2

Query: 506 AVSRAFGDRNLKSLLKSEPDVKVEDIDHTAELVVLASDGVWKVMNNREAVDVVKKYKDPQ 327
           A+ R  GD+ L + +   PDV  + ++   +LV    DG+W+    +   DVV       
Sbjct: 103 ALRRPVGDKLLVNGVNVMPDVH-KVLNQITDLVGRIHDGLWRGYTEKPITDVVNIGIGGS 161

Query: 326 TAAKQLIAEAVKRDSKDDISC 264
               +L++EA+   ++  + C
Sbjct: 162 FLGPELVSEALLSYAQKGVRC 182
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>PYRD_STRCO (Q9KXR7) Dihydroorotate dehydrogenase (EC 1.3.3.1) (Dihydroorotate|
           oxidase) (DHOdehase) (DHODase) (DHOD)
          Length = 368

 Score = 29.6 bits (65), Expect = 6.0
 Identities = 17/41 (41%), Positives = 23/41 (56%), Gaps = 1/41 (2%)
 Frame = -2

Query: 506 AVSRAFGDRNLKSLLKSEPDVKVEDIDHTAELVV-LASDGV 387
           A  RA   R +  L+K  PD+  ED+D  A+L V L  DG+
Sbjct: 207 AADRAVTARRVPLLVKIAPDLADEDVDAVADLAVELGLDGI 247


  Database: uniprot_sprot.fasta
    Posted date:  May 25, 2006  5:36 PM
  Number of letters in database: 80,573,946
  Number of sequences in database:  219,361
  
Lambda     K      H
   0.318    0.135    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 76,016,287
Number of Sequences: 219361
Number of extensions: 1418743
Number of successful extensions: 4071
Number of sequences better than 10.0: 63
Number of HSP's better than 10.0 without gapping: 3965
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4048
length of database: 80,573,946
effective HSP length: 105
effective length of database: 57,541,041
effective search space used: 4545742239
frameshift window, decay const: 50,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
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