>2AAB_ARATH (Q38950) Serine/threonine-protein phosphatase 2A 65 kDa regulatory|
subunit A beta isoform (PP2A, subunit A, beta isoform)
(AtA beta)
Length = 587
Score = 226 bits (576), Expect = 4e-59
Identities = 108/131 (82%), Positives = 123/131 (93%)
Frame = -2
Query: 611 AAANNLKRLAXEFGPEWAMQHIIPQVLEKINNPHYLYRMTILQAISLLAPVMGAEITCQK 432
AAANNLKRLA EFGPEWAMQHI+PQVLE +NNPHYLYRMTIL+A+SLLAPVMG+EITC K
Sbjct: 455 AAANNLKRLAEEFGPEWAMQHIVPQVLEMVNNPHYLYRMTILRAVSLLAPVMGSEITCSK 514
Query: 431 LLPVVINSSKDRVPNIKFNVAKVLQSLVPILDQSVAEKTVKPCLVELSEDPDVDVRYYAN 252
LLPVV+ +SKDRVPNIKFNVAKVLQSL+PI+DQSV EKT++P LVELSEDPDVDVR++AN
Sbjct: 515 LLPVVMTASKDRVPNIKFNVAKVLQSLIPIVDQSVVEKTIRPGLVELSEDPDVDVRFFAN 574
Query: 251 QALQACDQIMM 219
QALQ+ D +MM
Sbjct: 575 QALQSIDNVMM 585
Score = 67.0 bits (162), Expect = 4e-11
Identities = 35/116 (30%), Positives = 62/116 (53%)
Frame = -2
Query: 611 AAANNLKRLAXEFGPEWAMQHIIPQVLEKINNPHYLYRMTILQAISLLAPVMGAEITCQK 432
AAA + + PE A+QHI+P V E ++ R + I +APV+G + T +
Sbjct: 299 AAAGKVTKFCRILNPEIAIQHILPCVKELSSDSSQHVRSALASVIMGMAPVLGKDATIEH 358
Query: 431 LLPVVINSSKDRVPNIKFNVAKVLQSLVPILDQSVAEKTVKPCLVELSEDPDVDVR 264
LLP+ ++ KD P+++ N+ L + ++ + +++ P +VEL+ED VR
Sbjct: 359 LLPIFLSLLKDEFPDVRLNIISKLDQVNQVIGIDLLSQSLLPAIVELAEDRHWRVR 414
Score = 49.3 bits (116), Expect = 9e-06
Identities = 29/128 (22%), Positives = 55/128 (42%)
Frame = -2
Query: 605 ANNLKRLAXEFGPEWAMQHIIPQVLEKINNPHYLYRMTILQAISLLAPVMGAEITCQKLL 426
AN L L GPE ++P + + + R+ ++ ++ EI Q +L
Sbjct: 262 ANQLYELCEAVGPEPTRTELVPAYVRLLRDNEAEVRIAAAGKVTKFCRILNPEIAIQHIL 321
Query: 425 PVVINSSKDRVPNIKFNVAKVLQSLVPILDQSVAEKTVKPCLVELSEDPDVDVRYYANQA 246
P V S D +++ +A V+ + P+L + + + P + L +D DVR
Sbjct: 322 PCVKELSSDSSQHVRSALASVIMGMAPVLGKDATIEHLLPIFLSLLKDEFPDVRLNIISK 381
Query: 245 LQACDQIM 222
L +Q++
Sbjct: 382 LDQVNQVI 389
Score = 45.8 bits (107), Expect = 1e-04
Identities = 25/102 (24%), Positives = 47/102 (46%)
Frame = -2
Query: 569 PEWAMQHIIPQVLEKINNPHYLYRMTILQAISLLAPVMGAEITCQKLLPVVINSSKDRVP 390
P+ +QHI+P ++ + + R + + L +G E T +L+P + +D
Sbjct: 235 PQDCVQHILPVIVNFSQDKSWRVRYMVANQLYELCEAVGPEPTRTELVPAYVRLLRDNEA 294
Query: 389 NIKFNVAKVLQSLVPILDQSVAEKTVKPCLVELSEDPDVDVR 264
++ A + IL+ +A + + PC+ ELS D VR
Sbjct: 295 EVRIAAAGKVTKFCRILNPEIAIQHILPCVKELSSDSSQHVR 336
Score = 39.7 bits (91), Expect = 0.007
Identities = 26/119 (21%), Positives = 50/119 (42%)
Frame = -2
Query: 611 AAANNLKRLAXEFGPEWAMQHIIPQVLEKINNPHYLYRMTILQAISLLAPVMGAEITCQK 432
AAA NL + A ++ + + R+ ++ + L ++ + Q
Sbjct: 182 AAATNLGKFAATVESAHLKTDVMSMFEDLTQDDQDSVRLLAVEGCAALGKLLEPQDCVQH 241
Query: 431 LLPVVINSSKDRVPNIKFNVAKVLQSLVPILDQSVAEKTVKPCLVELSEDPDVDVRYYA 255
+LPV++N S+D+ +++ VA L L + + P V L D + +VR A
Sbjct: 242 ILPVIVNFSQDKSWRVRYMVANQLYELCEAVGPEPTRTELVPAYVRLLRDNEAEVRIAA 300
Score = 38.5 bits (88), Expect = 0.016
Identities = 25/108 (23%), Positives = 52/108 (48%)
Frame = -2
Query: 602 NNLKRLAXEFGPEWAMQHIIPQVLEKINNPHYLYRMTILQAISLLAPVMGAEITCQKLLP 423
+ L ++ G + Q ++P ++E + H+ R+ I++ I LLA +G KL
Sbjct: 380 SKLDQVNQVIGIDLLSQSLLPAIVELAEDRHWRVRLAIIEYIPLLASQLGVGFFDDKLGA 439
Query: 422 VVINSSKDRVPNIKFNVAKVLQSLVPILDQSVAEKTVKPCLVELSEDP 279
+ + +D+V +I+ A L+ L A + + P ++E+ +P
Sbjct: 440 LCMQWLQDKVHSIRDAAANNLKRLAEEFGPEWAMQHIVPQVLEMVNNP 487
Score = 36.6 bits (83), Expect = 0.059
Identities = 18/87 (20%), Positives = 44/87 (50%)
Frame = -2
Query: 611 AAANNLKRLAXEFGPEWAMQHIIPQVLEKINNPHYLYRMTILQAISLLAPVMGAEITCQK 432
A A+ + +A G + ++H++P L + + R+ I+ + + V+G ++ Q
Sbjct: 338 ALASVIMGMAPVLGKDATIEHLLPIFLSLLKDEFPDVRLNIISKLDQVNQVIGIDLLSQS 397
Query: 431 LLPVVINSSKDRVPNIKFNVAKVLQSL 351
LLP ++ ++DR ++ + + + L
Sbjct: 398 LLPAIVELAEDRHWRVRLAIIEYIPLL 424
>2AAG_ARATH (Q38951) Serine/threonine-protein phosphatase 2A 65 kDa regulatory|
subunit A gamma isoform (PP2A, subunit A, gamma isoform)
(AtA gamma)
Length = 587
Score = 225 bits (573), Expect = 9e-59
Identities = 106/131 (80%), Positives = 121/131 (92%)
Frame = -2
Query: 611 AAANNLKRLAXEFGPEWAMQHIIPQVLEKINNPHYLYRMTILQAISLLAPVMGAEITCQK 432
AAANNLKRLA EFGPEWAMQHI+PQVLE INNPHYLYRMTIL+A+SLLAPVMG+EITC K
Sbjct: 455 AAANNLKRLAEEFGPEWAMQHIVPQVLEMINNPHYLYRMTILRAVSLLAPVMGSEITCSK 514
Query: 431 LLPVVINSSKDRVPNIKFNVAKVLQSLVPILDQSVAEKTVKPCLVELSEDPDVDVRYYAN 252
LLP VI +SKDRVPNIKFNVAK++QSL+PI+DQ+V E ++PCLVELSEDPDVDVRY+AN
Sbjct: 515 LLPAVITASKDRVPNIKFNVAKMMQSLIPIVDQAVVENMIRPCLVELSEDPDVDVRYFAN 574
Query: 251 QALQACDQIMM 219
QALQ+ D +MM
Sbjct: 575 QALQSIDNVMM 585
Score = 67.4 bits (163), Expect = 3e-11
Identities = 35/116 (30%), Positives = 62/116 (53%)
Frame = -2
Query: 611 AAANNLKRLAXEFGPEWAMQHIIPQVLEKINNPHYLYRMTILQAISLLAPVMGAEITCQK 432
AAA + + PE A+QHI+P V E ++ R + I +APV+G + T +
Sbjct: 299 AAAGKVTKFCRILNPELAIQHILPCVKELSSDSSQHVRSALASVIMGMAPVLGKDATIEH 358
Query: 431 LLPVVINSSKDRVPNIKFNVAKVLQSLVPILDQSVAEKTVKPCLVELSEDPDVDVR 264
LLP+ ++ KD P+++ N+ L + ++ + +++ P +VEL+ED VR
Sbjct: 359 LLPIFLSLLKDEFPDVRLNIISKLDQVNQVIGIDLLSQSLLPAIVELAEDRHWRVR 414
Score = 46.2 bits (108), Expect = 7e-05
Identities = 28/128 (21%), Positives = 54/128 (42%)
Frame = -2
Query: 605 ANNLKRLAXEFGPEWAMQHIIPQVLEKINNPHYLYRMTILQAISLLAPVMGAEITCQKLL 426
AN L L GPE ++P + + R+ ++ ++ E+ Q +L
Sbjct: 262 ANQLYELCEAVGPEPTRTDLVPAYARLLCDNEAEVRIAAAGKVTKFCRILNPELAIQHIL 321
Query: 425 PVVINSSKDRVPNIKFNVAKVLQSLVPILDQSVAEKTVKPCLVELSEDPDVDVRYYANQA 246
P V S D +++ +A V+ + P+L + + + P + L +D DVR
Sbjct: 322 PCVKELSSDSSQHVRSALASVIMGMAPVLGKDATIEHLLPIFLSLLKDEFPDVRLNIISK 381
Query: 245 LQACDQIM 222
L +Q++
Sbjct: 382 LDQVNQVI 389
Score = 39.3 bits (90), Expect = 0.009
Identities = 25/108 (23%), Positives = 53/108 (49%)
Frame = -2
Query: 602 NNLKRLAXEFGPEWAMQHIIPQVLEKINNPHYLYRMTILQAISLLAPVMGAEITCQKLLP 423
+ L ++ G + Q ++P ++E + H+ R+ I++ I LLA +G +KL
Sbjct: 380 SKLDQVNQVIGIDLLSQSLLPAIVELAEDRHWRVRLAIIEYIPLLASQLGVGFFDEKLGA 439
Query: 422 VVINSSKDRVPNIKFNVAKVLQSLVPILDQSVAEKTVKPCLVELSEDP 279
+ + +D+V +I+ A L+ L A + + P ++E+ +P
Sbjct: 440 LCMQWLQDKVHSIREAAANNLKRLAEEFGPEWAMQHIVPQVLEMINNP 487
Score = 38.5 bits (88), Expect = 0.016
Identities = 24/102 (23%), Positives = 43/102 (42%)
Frame = -2
Query: 569 PEWAMQHIIPQVLEKINNPHYLYRMTILQAISLLAPVMGAEITCQKLLPVVINSSKDRVP 390
P+ + HI+P ++ + + R + + L +G E T L+P D
Sbjct: 235 PQDCVAHILPVIVNFSQDKSWRVRYMVANQLYELCEAVGPEPTRTDLVPAYARLLCDNEA 294
Query: 389 NIKFNVAKVLQSLVPILDQSVAEKTVKPCLVELSEDPDVDVR 264
++ A + IL+ +A + + PC+ ELS D VR
Sbjct: 295 EVRIAAAGKVTKFCRILNPELAIQHILPCVKELSSDSSQHVR 336
Score = 37.0 bits (84), Expect = 0.045
Identities = 23/124 (18%), Positives = 57/124 (45%)
Frame = -2
Query: 611 AAANNLKRLAXEFGPEWAMQHIIPQVLEKINNPHYLYRMTILQAISLLAPVMGAEITCQK 432
A A+ + +A G + ++H++P L + + R+ I+ + + V+G ++ Q
Sbjct: 338 ALASVIMGMAPVLGKDATIEHLLPIFLSLLKDEFPDVRLNIISKLDQVNQVIGIDLLSQS 397
Query: 431 LLPVVINSSKDRVPNIKFNVAKVLQSLVPILDQSVAEKTVKPCLVELSEDPDVDVRYYAN 252
LLP ++ ++DR ++ + + + L L ++ + ++ +D +R A
Sbjct: 398 LLPAIVELAEDRHWRVRLAIIEYIPLLASQLGVGFFDEKLGALCMQWLQDKVHSIREAAA 457
Query: 251 QALQ 240
L+
Sbjct: 458 NNLK 461
Score = 35.0 bits (79), Expect = 0.17
Identities = 25/119 (21%), Positives = 48/119 (40%)
Frame = -2
Query: 611 AAANNLKRLAXEFGPEWAMQHIIPQVLEKINNPHYLYRMTILQAISLLAPVMGAEITCQK 432
AAA NL + A I+ + + R+ ++ + L ++ +
Sbjct: 182 AAATNLGKFAATIESAHLKTDIMSMFEDLTQDDQDSVRLLAVEGCAALGKLLEPQDCVAH 241
Query: 431 LLPVVINSSKDRVPNIKFNVAKVLQSLVPILDQSVAEKTVKPCLVELSEDPDVDVRYYA 255
+LPV++N S+D+ +++ VA L L + + P L D + +VR A
Sbjct: 242 ILPVIVNFSQDKSWRVRYMVANQLYELCEAVGPEPTRTDLVPAYARLLCDNEAEVRIAA 300
>2AAA_PEA (P36875) Protein phosphatase PP2A regulatory subunit A (PR65)|
(Fragment)
Length = 395
Score = 212 bits (540), Expect = 6e-55
Identities = 103/132 (78%), Positives = 121/132 (91%), Gaps = 1/132 (0%)
Frame = -2
Query: 611 AAANNLKRLAXE-FGPEWAMQHIIPQVLEKINNPHYLYRMTILQAISLLAPVMGAEITCQ 435
AAANN+KRLA E FGPEWAMQHIIPQVL+ IN+PHYLYRMTIL AISLLAPV+G+EIT
Sbjct: 262 AAANNVKRLAAEEFGPEWAMQHIIPQVLDMINDPHYLYRMTILHAISLLAPVLGSEITST 321
Query: 434 KLLPVVINSSKDRVPNIKFNVAKVLQSLVPILDQSVAEKTVKPCLVELSEDPDVDVRYYA 255
LLP+V+N+SKDRVPNIKFNVAKVLQSL+PI+D+SV E T++PCLVELSEDPDVDVR++A
Sbjct: 322 NLLPLVVNASKDRVPNIKFNVAKVLQSLIPIVDESVVESTIRPCLVELSEDPDVDVRFFA 381
Query: 254 NQALQACDQIMM 219
+QALQ+ DQ+ M
Sbjct: 382 SQALQSSDQVKM 393
Score = 68.6 bits (166), Expect = 1e-11
Identities = 35/116 (30%), Positives = 63/116 (54%)
Frame = -2
Query: 611 AAANNLKRLAXEFGPEWAMQHIIPQVLEKINNPHYLYRMTILQAISLLAPVMGAEITCQK 432
AAA + + + PE A+QHI+P V E + R + I +APV+G + T ++
Sbjct: 106 AAAGKVSKFSRILSPELAIQHILPCVKELSTDSSQHVRSALASVIMGMAPVLGKDATIEQ 165
Query: 431 LLPVVINSSKDRVPNIKFNVAKVLQSLVPILDQSVAEKTVKPCLVELSEDPDVDVR 264
LLP+ ++ KD P+++ N+ L + ++ + +++ P +VEL+ED VR
Sbjct: 166 LLPIFLSLLKDEFPDVRLNIISKLDQVNQVIGIDLLSQSLLPAIVELAEDRHWRVR 221
Score = 48.1 bits (113), Expect = 2e-05
Identities = 28/128 (21%), Positives = 56/128 (43%)
Frame = -2
Query: 605 ANNLKRLAXEFGPEWAMQHIIPQVLEKINNPHYLYRMTILQAISLLAPVMGAEITCQKLL 426
AN L L GP+ ++P + + + R+ +S + ++ E+ Q +L
Sbjct: 69 ANQLYELCEAVGPDSTKTELVPAYVRLLRDNVAEVRIAAAGKVSKFSRILSPELAIQHIL 128
Query: 425 PVVINSSKDRVPNIKFNVAKVLQSLVPILDQSVAEKTVKPCLVELSEDPDVDVRYYANQA 246
P V S D +++ +A V+ + P+L + + + P + L +D DVR
Sbjct: 129 PCVKELSTDSSQHVRSALASVIMGMAPVLGKDATIEQLLPIFLSLLKDEFPDVRLNIISK 188
Query: 245 LQACDQIM 222
L +Q++
Sbjct: 189 LDQVNQVI 196
Score = 43.9 bits (102), Expect = 4e-04
Identities = 24/102 (23%), Positives = 46/102 (45%)
Frame = -2
Query: 569 PEWAMQHIIPQVLEKINNPHYLYRMTILQAISLLAPVMGAEITCQKLLPVVINSSKDRVP 390
P+ + HI+P ++ + + R + + L +G + T +L+P + +D V
Sbjct: 42 PQDCLAHILPVIVNFSQDKSWRVRYMVANQLYELCEAVGPDSTKTELVPAYVRLLRDNVA 101
Query: 389 NIKFNVAKVLQSLVPILDQSVAEKTVKPCLVELSEDPDVDVR 264
++ A + IL +A + + PC+ ELS D VR
Sbjct: 102 EVRIAAAGKVSKFSRILSPELAIQHILPCVKELSTDSSQHVR 143
Score = 36.2 bits (82), Expect = 0.077
Identities = 20/116 (17%), Positives = 54/116 (46%)
Frame = -2
Query: 611 AAANNLKRLAXEFGPEWAMQHIIPQVLEKINNPHYLYRMTILQAISLLAPVMGAEITCQK 432
A A+ + +A G + ++ ++P L + + R+ I+ + + V+G ++ Q
Sbjct: 145 ALASVIMGMAPVLGKDATIEQLLPIFLSLLKDEFPDVRLNIISKLDQVNQVIGIDLLSQS 204
Query: 431 LLPVVINSSKDRVPNIKFNVAKVLQSLVPILDQSVAEKTVKPCLVELSEDPDVDVR 264
LLP ++ ++DR ++ + + + L L + + +++ +D + +R
Sbjct: 205 LLPAIVELAEDRHWRVRLAIIEYIPLLASQLGVGFFDDKLGALIMQWLKDKEYSIR 260
Score = 33.9 bits (76), Expect = 0.38
Identities = 19/83 (22%), Positives = 38/83 (45%)
Frame = -2
Query: 503 YRMTILQAISLLAPVMGAEITCQKLLPVVINSSKDRVPNIKFNVAKVLQSLVPILDQSVA 324
+R ++ + L ++ + +LPV++N S+D+ +++ VA L L +
Sbjct: 25 FRFLAVEGCAALGKLLEPQDCLAHILPVIVNFSQDKSWRVRYMVANQLYELCEAVGPDST 84
Query: 323 EKTVKPCLVELSEDPDVDVRYYA 255
+ + P V L D +VR A
Sbjct: 85 KTELVPAYVRLLRDNVAEVRIAA 107
>2AAA_ARATH (Q38845) Serine/threonine-protein phosphatase 2A 65 kDa regulatory|
subunit A alpha isoform (PP2A, subunit A, alpha isoform)
(PR-65 A) (AtA alpha) (Protein enhanced
ethylene-response 1) (Protein ROOTS CURL IN
NAPHTHYLPHTHALAMIC ACID 1)
Length = 588
Score = 211 bits (537), Expect = 1e-54
Identities = 97/127 (76%), Positives = 117/127 (92%)
Frame = -2
Query: 611 AAANNLKRLAXEFGPEWAMQHIIPQVLEKINNPHYLYRMTILQAISLLAPVMGAEITCQK 432
AAANNLKRLA EFGPEWAMQH++PQVL+ +NNPHYL+RM +L+AISL+APVMG+EITC K
Sbjct: 455 AAANNLKRLAEEFGPEWAMQHLVPQVLDMVNNPHYLHRMMVLRAISLMAPVMGSEITCSK 514
Query: 431 LLPVVINSSKDRVPNIKFNVAKVLQSLVPILDQSVAEKTVKPCLVELSEDPDVDVRYYAN 252
LPVV+ +SKDRVPNIKFNVAK+LQSL+PI+DQSV +KT++ CLV+LSEDPDVDVRY+AN
Sbjct: 515 FLPVVVEASKDRVPNIKFNVAKLLQSLIPIVDQSVVDKTIRQCLVDLSEDPDVDVRYFAN 574
Query: 251 QALQACD 231
QAL + D
Sbjct: 575 QALNSID 581
Score = 66.6 bits (161), Expect = 5e-11
Identities = 34/116 (29%), Positives = 62/116 (53%)
Frame = -2
Query: 611 AAANNLKRLAXEFGPEWAMQHIIPQVLEKINNPHYLYRMTILQAISLLAPVMGAEITCQK 432
AAA + + PE A+QHI+P V E ++ R + I +AP++G + T +
Sbjct: 299 AAAGKVTKFCRLLNPELAIQHILPCVKELSSDSSQHVRSALASVIMGMAPILGKDSTIEH 358
Query: 431 LLPVVINSSKDRVPNIKFNVAKVLQSLVPILDQSVAEKTVKPCLVELSEDPDVDVR 264
LLP+ ++ KD P+++ N+ L + ++ + +++ P +VEL+ED VR
Sbjct: 359 LLPIFLSLLKDEFPDVRLNIISKLDQVNQVIGIDLLSQSLLPAIVELAEDRHWRVR 414
Score = 46.6 bits (109), Expect = 6e-05
Identities = 28/128 (21%), Positives = 55/128 (42%)
Frame = -2
Query: 605 ANNLKRLAXEFGPEWAMQHIIPQVLEKINNPHYLYRMTILQAISLLAPVMGAEITCQKLL 426
AN L L GP+ ++P + + + R+ ++ ++ E+ Q +L
Sbjct: 262 ANQLYELCEAVGPDCTRTDLVPAYVRLLRDNEAEVRIAAAGKVTKFCRLLNPELAIQHIL 321
Query: 425 PVVINSSKDRVPNIKFNVAKVLQSLVPILDQSVAEKTVKPCLVELSEDPDVDVRYYANQA 246
P V S D +++ +A V+ + PIL + + + P + L +D DVR
Sbjct: 322 PCVKELSSDSSQHVRSALASVIMGMAPILGKDSTIEHLLPIFLSLLKDEFPDVRLNIISK 381
Query: 245 LQACDQIM 222
L +Q++
Sbjct: 382 LDQVNQVI 389
Score = 41.6 bits (96), Expect = 0.002
Identities = 26/119 (21%), Positives = 53/119 (44%)
Frame = -2
Query: 611 AAANNLKRLAXEFGPEWAMQHIIPQVLEKINNPHYLYRMTILQAISLLAPVMGAEITCQK 432
AAA+NL + A + + I+ + + R+ ++ + L ++ + +
Sbjct: 182 AAASNLGKFATTVESTFLIAEIMTMFDDLTKDDQDSVRLLAVEGCAALGKLLEPQDCVAR 241
Query: 431 LLPVVINSSKDRVPNIKFNVAKVLQSLVPILDQSVAEKTVKPCLVELSEDPDVDVRYYA 255
+LPV++N S+D+ +++ VA L L + + P V L D + +VR A
Sbjct: 242 ILPVIVNFSQDKSWRVRYMVANQLYELCEAVGPDCTRTDLVPAYVRLLRDNEAEVRIAA 300
Score = 37.7 bits (86), Expect = 0.027
Identities = 21/102 (20%), Positives = 44/102 (43%)
Frame = -2
Query: 569 PEWAMQHIIPQVLEKINNPHYLYRMTILQAISLLAPVMGAEITCQKLLPVVINSSKDRVP 390
P+ + I+P ++ + + R + + L +G + T L+P + +D
Sbjct: 235 PQDCVARILPVIVNFSQDKSWRVRYMVANQLYELCEAVGPDCTRTDLVPAYVRLLRDNEA 294
Query: 389 NIKFNVAKVLQSLVPILDQSVAEKTVKPCLVELSEDPDVDVR 264
++ A + +L+ +A + + PC+ ELS D VR
Sbjct: 295 EVRIAAAGKVTKFCRLLNPELAIQHILPCVKELSSDSSQHVR 336
Score = 35.8 bits (81), Expect = 0.10
Identities = 26/127 (20%), Positives = 58/127 (45%)
Frame = -2
Query: 602 NNLKRLAXEFGPEWAMQHIIPQVLEKINNPHYLYRMTILQAISLLAPVMGAEITCQKLLP 423
+ L ++ G + Q ++P ++E + H+ R+ I++ + LLA +G KL
Sbjct: 380 SKLDQVNQVIGIDLLSQSLLPAIVELAEDRHWRVRLAIIEYVPLLASQLGIGFFDDKLGA 439
Query: 422 VVINSSKDRVPNIKFNVAKVLQSLVPILDQSVAEKTVKPCLVELSEDPDVDVRYYANQAL 243
+ + +D+V +I+ A L+ L A + + P ++++ +P R +A+
Sbjct: 440 LCMQWLQDKVYSIREAAANNLKRLAEEFGPEWAMQHLVPQVLDMVNNPHYLHRMMVLRAI 499
Query: 242 QACDQIM 222
+M
Sbjct: 500 SLMAPVM 506
>2AAB_PIG (P54613) Serine/threonine-protein phosphatase 2A 65 kDa regulatory|
subunit A beta isoform (PP2A, subunit A, PR65-beta
isoform) (PP2A, subunit A, R1-beta isoform) (Fragment)
Length = 602
Score = 124 bits (312), Expect = 2e-28
Identities = 58/123 (47%), Positives = 87/123 (70%)
Frame = -2
Query: 611 AAANNLKRLAXEFGPEWAMQHIIPQVLEKINNPHYLYRMTILQAISLLAPVMGAEITCQK 432
AA NNL +L +FG EWA I+P+VL N+P+YL+RMT L I++L+ G EIT ++
Sbjct: 474 AATNNLMKLVQKFGTEWAQNTIVPKVLVMANDPNYLHRMTTLFCINVLSEACGQEITTKQ 533
Query: 431 LLPVVINSSKDRVPNIKFNVAKVLQSLVPILDQSVAEKTVKPCLVELSEDPDVDVRYYAN 252
+LP+V+ + D+V N++FNVAK LQ + PILD ++ VKP L +L +D D+DV+Y+A
Sbjct: 534 MLPIVLKMAGDQVANVRFNVAKSLQKIGPILDTDALQEEVKPVLQKLGQDEDMDVKYFAQ 593
Query: 251 QAL 243
+A+
Sbjct: 594 EAI 596
Score = 50.4 bits (119), Expect = 4e-06
Identities = 31/120 (25%), Positives = 58/120 (48%), Gaps = 4/120 (3%)
Frame = -2
Query: 611 AAANNLKRLAXEFGPEWA----MQHIIPQVLEKINNPHYLYRMTILQAISLLAPVMGAEI 444
AAA+ +K L E M I+P + E +++ + + + I L+ ++G E
Sbjct: 314 AAAHKVKELCENLPIEGRETIIMNQILPCIKELVSDTNQHVKSALASVIMGLSTILGKEN 373
Query: 443 TCQKLLPVVINSSKDRVPNIKFNVAKVLQSLVPILDQSVAEKTVKPCLVELSEDPDVDVR 264
T + LLP+ + KD P ++ N+ L + ++ +++ P +VEL+ED VR
Sbjct: 374 TIEHLLPLFLAQLKDECPEVRLNIISNLDCVNEVIGIRQLSQSLLPAIVELAEDAKWRVR 433
Score = 32.0 bits (71), Expect = 1.5
Identities = 18/82 (21%), Positives = 35/82 (42%)
Frame = -2
Query: 506 LYRMTILQAISLLAPVMGAEITCQKLLPVVINSSKDRVPNIKFNVAKVLQSLVPILDQSV 327
+ R + A V+ + +++P+ N + D +++ + S+ +L Q
Sbjct: 193 MVRRAAASKLGEFAKVLELDSVKSEIVPLFTNLASDEQDSVRLLAVEACVSIAQLLSQDD 252
Query: 326 AEKTVKPCLVELSEDPDVDVRY 261
E V P L + +ED VRY
Sbjct: 253 LEALVMPTLRQAAEDKSWRVRY 274
>2AAB_RAT (Q4QQT4) Serine/threonine-protein phosphatase 2A 65 kDa regulatory|
subunit A beta isoform (PP2A, subunit A, PR65-beta
isoform) (PP2A, subunit A, R1-beta isoform)
Length = 601
Score = 123 bits (308), Expect = 5e-28
Identities = 58/123 (47%), Positives = 86/123 (69%)
Frame = -2
Query: 611 AAANNLKRLAXEFGPEWAMQHIIPQVLEKINNPHYLYRMTILQAISLLAPVMGAEITCQK 432
AA NNL +L +FG EWA I+P+VL N+P+YL+RMT L I+ L+ G EIT ++
Sbjct: 473 AATNNLMKLVQKFGTEWAQNTIVPKVLVMANDPNYLHRMTTLFCINALSEACGKEITTKQ 532
Query: 431 LLPVVINSSKDRVPNIKFNVAKVLQSLVPILDQSVAEKTVKPCLVELSEDPDVDVRYYAN 252
+LP+V+ + D+V N++FNVAK LQ + PILD + + VKP L +L +D D+DV+Y+A
Sbjct: 533 MLPIVLKMAGDQVANVRFNVAKSLQKIGPILDTNALQGEVKPVLQKLGQDEDMDVKYFAQ 592
Query: 251 QAL 243
+A+
Sbjct: 593 EAI 595
Score = 51.2 bits (121), Expect = 2e-06
Identities = 31/120 (25%), Positives = 58/120 (48%), Gaps = 4/120 (3%)
Frame = -2
Query: 611 AAANNLKRLAXEFGPEWA----MQHIIPQVLEKINNPHYLYRMTILQAISLLAPVMGAEI 444
AAA+ ++ L E M I+P + E +++ + + + I L+ V+G E
Sbjct: 313 AAAHKVRELCENLPTEGRETVIMNQILPYIKELVSDTNQHVKSALASVIMGLSTVLGKEN 372
Query: 443 TCQKLLPVVINSSKDRVPNIKFNVAKVLQSLVPILDQSVAEKTVKPCLVELSEDPDVDVR 264
T + LLP+ + KD P ++ N+ L + ++ +++ P +VEL+ED VR
Sbjct: 373 TIEHLLPLFLAQLKDECPEVRLNIISNLDCVNEVIGIRQLSQSLLPAIVELAEDAKWRVR 432
Score = 31.6 bits (70), Expect = 1.9
Identities = 18/82 (21%), Positives = 35/82 (42%)
Frame = -2
Query: 506 LYRMTILQAISLLAPVMGAEITCQKLLPVVINSSKDRVPNIKFNVAKVLQSLVPILDQSV 327
+ R + A V+ + +++P+ N + D +++ + S+ +L Q
Sbjct: 192 MVRRAAASKLGEFAKVLELDSVKTEIVPLFTNLASDEQDSVRLLAVEACVSIAQLLSQDD 251
Query: 326 AEKTVKPCLVELSEDPDVDVRY 261
E V P L + +ED VRY
Sbjct: 252 LEALVMPTLRQAAEDKSWRVRY 273
Score = 29.3 bits (64), Expect = 9.5
Identities = 23/130 (17%), Positives = 55/130 (42%), Gaps = 1/130 (0%)
Frame = -2
Query: 611 AAANNLKRLAXEFGPEWAMQHIIPQVLEKINNPHYLYRMTILQAISLLAPVMGAEITCQK 432
AAA+ L A + I+P ++ R+ ++A +A ++ +
Sbjct: 196 AAASKLGEFAKVLELDSVKTEIVPLFTNLASDEQDSVRLLAVEACVSIAQLLSQDDLEAL 255
Query: 431 LLPVVINSSKDRVPNIKFNVAKVLQSLVPILDQSVAEKTVKPCLVELSEDPDVDVR-YYA 255
++P + +++D+ +++ VA L + +A + P L D + +VR A
Sbjct: 256 VMPTLRQAAEDKSWRVRYMVADKFSELQKAVGPKIALSDLIPAFQSLLRDCEAEVRAAAA 315
Query: 254 NQALQACDQI 225
++ + C+ +
Sbjct: 316 HKVRELCENL 325
>2AAB_MOUSE (Q7TNP2) Serine/threonine-protein phosphatase 2A 65 kDa regulatory|
subunit A beta isoform (PP2A, subunit A, PR65-beta
isoform) (PP2A, subunit A, R1-beta isoform)
Length = 601
Score = 123 bits (308), Expect = 5e-28
Identities = 58/123 (47%), Positives = 86/123 (69%)
Frame = -2
Query: 611 AAANNLKRLAXEFGPEWAMQHIIPQVLEKINNPHYLYRMTILQAISLLAPVMGAEITCQK 432
AA NNL +L +FG EWA I+P+VL N+P+YL+RMT L I+ L+ G EIT ++
Sbjct: 473 AATNNLMKLVQKFGTEWAQNTIVPKVLVMANDPNYLHRMTTLFCINALSEACGKEITTKQ 532
Query: 431 LLPVVINSSKDRVPNIKFNVAKVLQSLVPILDQSVAEKTVKPCLVELSEDPDVDVRYYAN 252
+LP+V+ + D+V N++FNVAK LQ + PILD + + VKP L +L +D D+DV+Y+A
Sbjct: 533 MLPIVLKMAGDQVANVRFNVAKSLQKIGPILDTNALQGEVKPVLQKLGQDEDMDVKYFAQ 592
Query: 251 QAL 243
+A+
Sbjct: 593 EAI 595
Score = 50.4 bits (119), Expect = 4e-06
Identities = 31/120 (25%), Positives = 57/120 (47%), Gaps = 4/120 (3%)
Frame = -2
Query: 611 AAANNLKRLAXEFGPEWA----MQHIIPQVLEKINNPHYLYRMTILQAISLLAPVMGAEI 444
AAA+ ++ L E M I+P + E +++ + + I L+ V+G E
Sbjct: 313 AAAHKVRELCENLPAEGRETVIMNQILPYIKELVSDTSQHVKSALASVIMGLSTVLGKEN 372
Query: 443 TCQKLLPVVINSSKDRVPNIKFNVAKVLQSLVPILDQSVAEKTVKPCLVELSEDPDVDVR 264
T + LLP+ + KD P ++ N+ L + ++ +++ P +VEL+ED VR
Sbjct: 373 TIEHLLPLFLAQLKDECPEVRLNIISNLDCVNEVIGIRQLSQSLLPAIVELAEDAKWRVR 432
Score = 30.4 bits (67), Expect = 4.2
Identities = 17/69 (24%), Positives = 32/69 (46%)
Frame = -2
Query: 467 APVMGAEITCQKLLPVVINSSKDRVPNIKFNVAKVLQSLVPILDQSVAEKTVKPCLVELS 288
A V+ + +++P+ N + D +++ + S+ +L Q E V P L + +
Sbjct: 205 AKVLELDSVKTEIVPLFTNLASDEQDSVRLLAVEACVSIAQLLSQEDLEALVIPTLRQAA 264
Query: 287 EDPDVDVRY 261
ED VRY
Sbjct: 265 EDKSWRVRY 273
Score = 30.4 bits (67), Expect = 4.2
Identities = 24/130 (18%), Positives = 55/130 (42%), Gaps = 1/130 (0%)
Frame = -2
Query: 611 AAANNLKRLAXEFGPEWAMQHIIPQVLEKINNPHYLYRMTILQAISLLAPVMGAEITCQK 432
AAA+ L A + I+P ++ R+ ++A +A ++ E
Sbjct: 196 AAASKLGEFAKVLELDSVKTEIVPLFTNLASDEQDSVRLLAVEACVSIAQLLSQEDLEAL 255
Query: 431 LLPVVINSSKDRVPNIKFNVAKVLQSLVPILDQSVAEKTVKPCLVELSEDPDVDVR-YYA 255
++P + +++D+ +++ VA L + +A + P L D + +VR A
Sbjct: 256 VIPTLRQAAEDKSWRVRYMVADKFSELQKAVGPKIALSDLIPAFQSLLRDCEAEVRAAAA 315
Query: 254 NQALQACDQI 225
++ + C+ +
Sbjct: 316 HKVRELCENL 325
>2AAB_HUMAN (P30154) Serine/threonine-protein phosphatase 2A 65 kDa regulatory|
subunit A beta isoform (PP2A, subunit A, PR65-beta
isoform) (PP2A, subunit A, R1-beta isoform)
Length = 601
Score = 123 bits (308), Expect = 5e-28
Identities = 58/123 (47%), Positives = 86/123 (69%)
Frame = -2
Query: 611 AAANNLKRLAXEFGPEWAMQHIIPQVLEKINNPHYLYRMTILQAISLLAPVMGAEITCQK 432
AA NNL +L +FG EWA I+P+VL N+P+YL+RMT L I+ L+ G EIT ++
Sbjct: 473 AATNNLMKLVQKFGTEWAQNTIVPKVLVMANDPNYLHRMTTLFCINALSEACGQEITTKQ 532
Query: 431 LLPVVINSSKDRVPNIKFNVAKVLQSLVPILDQSVAEKTVKPCLVELSEDPDVDVRYYAN 252
+LP+V+ + D+V N++FNVAK LQ + PILD + + VKP L +L +D D+DV+Y+A
Sbjct: 533 MLPIVLKMAGDQVANVRFNVAKSLQKIGPILDTNALQGEVKPVLQKLGQDEDMDVKYFAQ 592
Query: 251 QAL 243
+A+
Sbjct: 593 EAI 595
Score = 51.2 bits (121), Expect = 2e-06
Identities = 31/120 (25%), Positives = 59/120 (49%), Gaps = 4/120 (3%)
Frame = -2
Query: 611 AAANNLKRLAXEFGPE----WAMQHIIPQVLEKINNPHYLYRMTILQAISLLAPVMGAEI 444
AAA+ +K L E M I+P + E +++ + + + I L+ ++G E
Sbjct: 313 AAAHKVKELGENLPIEDRETIIMNQILPYIKELVSDTNQHVKSALASVIMGLSTILGKEN 372
Query: 443 TCQKLLPVVINSSKDRVPNIKFNVAKVLQSLVPILDQSVAEKTVKPCLVELSEDPDVDVR 264
T + LLP+ + KD P+++ N+ L + ++ +++ P +VEL+ED VR
Sbjct: 373 TIEHLLPLFLAQLKDECPDVRLNIISNLDCVNEVIGIRQLSQSLLPAIVELAEDAKWRVR 432
Score = 30.0 bits (66), Expect = 5.6
Identities = 17/82 (20%), Positives = 35/82 (42%)
Frame = -2
Query: 506 LYRMTILQAISLLAPVMGAEITCQKLLPVVINSSKDRVPNIKFNVAKVLQSLVPILDQSV 327
+ R + A V+ + +++P+ + + D +++ + S+ +L Q
Sbjct: 192 MVRRAAASKLGEFAKVLELDSVKSEIVPLFTSLASDEQDSVRLLAVEACVSIAQLLSQDD 251
Query: 326 AEKTVKPCLVELSEDPDVDVRY 261
E V P L + +ED VRY
Sbjct: 252 LETLVMPTLRQAAEDKSWRVRY 273
>2AAA_PIG (P54612) Serine/threonine-protein phosphatase 2A 65 kDa regulatory|
subunit A alpha isoform (PP2A, subunit A, PR65-alpha
isoform) (PP2A, subunit A, R1-alpha isoform)
Length = 588
Score = 123 bits (308), Expect = 5e-28
Identities = 61/123 (49%), Positives = 86/123 (69%)
Frame = -2
Query: 611 AAANNLKRLAXEFGPEWAMQHIIPQVLEKINNPHYLYRMTILQAISLLAPVMGAEITCQK 432
AA +NLK+L +FG EWA IIP+VL +P+YL+RMT L I++L+ V G +IT +
Sbjct: 460 AATSNLKKLVEKFGKEWAHATIIPKVLAMSGDPNYLHRMTTLFCINVLSEVCGQDITTKH 519
Query: 431 LLPVVINSSKDRVPNIKFNVAKVLQSLVPILDQSVAEKTVKPCLVELSEDPDVDVRYYAN 252
+LP V+ + D V N++FNVAK LQ + PILD S + VKP L +L++D DVDV+Y+A
Sbjct: 520 MLPTVLRMAGDPVANVRFNVAKSLQKIGPILDNSTLQSEVKPILEKLTQDQDVDVKYFAQ 579
Query: 251 QAL 243
+AL
Sbjct: 580 EAL 582
Score = 50.4 bits (119), Expect = 4e-06
Identities = 25/98 (25%), Positives = 51/98 (52%)
Frame = -2
Query: 557 MQHIIPQVLEKINNPHYLYRMTILQAISLLAPVMGAEITCQKLLPVVINSSKDRVPNIKF 378
M I+P + E +++ + + + I L+P++G + T + LLP+ + KD P ++
Sbjct: 322 MTQILPCIKELVSDANQHVKSALASVIMGLSPILGKDNTIEHLLPLFLAQLKDECPEVRL 381
Query: 377 NVAKVLQSLVPILDQSVAEKTVKPCLVELSEDPDVDVR 264
N+ L + ++ +++ P +VEL+ED VR
Sbjct: 382 NIISNLDCVNEVIGIRQLSQSLLPAIVELAEDAKWRVR 419
Score = 33.1 bits (74), Expect = 0.66
Identities = 30/137 (21%), Positives = 54/137 (39%), Gaps = 4/137 (2%)
Frame = -2
Query: 548 IIPQVLEKINNPHYLYRMTILQAISLLAPVMGAEITCQKLLPVVINSSKDRVPNIK---- 381
++P + + + + R + + L +G EIT L+P N KD ++
Sbjct: 243 VMPTLRQAAEDKSWRVRYMVADKFTELQKAVGPEITKTDLVPAFQNLMKDCEAEVRAAAS 302
Query: 380 FNVAKVLQSLVPILDQSVAEKTVKPCLVELSEDPDVDVRYYANQALQACDQIMMXXXXXX 201
V + ++L ++V + PC+ EL D + V+ + I+
Sbjct: 303 HKVKEFCENLSADCRENVIMTQILPCIKELVSDANQHVKSALASVIMGLSPIL--GKDNT 360
Query: 200 XCHVL*KLFLVQLWSTC 150
H+L LFL QL C
Sbjct: 361 IEHLL-PLFLAQLKDEC 376
Score = 30.4 bits (67), Expect = 4.2
Identities = 23/124 (18%), Positives = 53/124 (42%)
Frame = -2
Query: 611 AAANNLKRLAXEFGPEWAMQHIIPQVLEKINNPHYLYRMTILQAISLLAPVMGAEITCQK 432
AAA+ L A + IIP ++ R+ ++A +A ++ E
Sbjct: 183 AAASKLGEFAKVLELDNVKSEIIPMFSNLASDEQDSVRLLAVEACVNIAQLLPQEDLEAL 242
Query: 431 LLPVVINSSKDRVPNIKFNVAKVLQSLVPILDQSVAEKTVKPCLVELSEDPDVDVRYYAN 252
++P + +++D+ +++ VA L + + + + P L +D + +VR A+
Sbjct: 243 VMPTLRQAAEDKSWRVRYMVADKFTELQKAVGPEITKTDLVPAFQNLMKDCEAEVRAAAS 302
Query: 251 QALQ 240
++
Sbjct: 303 HKVK 306
Score = 30.0 bits (66), Expect = 5.6
Identities = 17/82 (20%), Positives = 35/82 (42%)
Frame = -2
Query: 506 LYRMTILQAISLLAPVMGAEITCQKLLPVVINSSKDRVPNIKFNVAKVLQSLVPILDQSV 327
+ R + A V+ + +++P+ N + D +++ + ++ +L Q
Sbjct: 179 MVRRAAASKLGEFAKVLELDNVKSEIIPMFSNLASDEQDSVRLLAVEACVNIAQLLPQED 238
Query: 326 AEKTVKPCLVELSEDPDVDVRY 261
E V P L + +ED VRY
Sbjct: 239 LEALVMPTLRQAAEDKSWRVRY 260
>2AAA_MOUSE (Q76MZ3) Serine/threonine-protein phosphatase 2A 65 kDa regulatory|
subunit A alpha isoform (PP2A, subunit A, PR65-alpha
isoform) (PP2A, subunit A, R1-alpha isoform)
Length = 588
Score = 123 bits (308), Expect = 5e-28
Identities = 61/123 (49%), Positives = 86/123 (69%)
Frame = -2
Query: 611 AAANNLKRLAXEFGPEWAMQHIIPQVLEKINNPHYLYRMTILQAISLLAPVMGAEITCQK 432
AA +NLK+L +FG EWA IIP+VL +P+YL+RMT L I++L+ V G +IT +
Sbjct: 460 AATSNLKKLVEKFGKEWAHATIIPKVLAMSGDPNYLHRMTTLFCINVLSEVCGQDITTKH 519
Query: 431 LLPVVINSSKDRVPNIKFNVAKVLQSLVPILDQSVAEKTVKPCLVELSEDPDVDVRYYAN 252
+LP V+ + D V N++FNVAK LQ + PILD S + VKP L +L++D DVDV+Y+A
Sbjct: 520 MLPTVLRMAGDPVANVRFNVAKSLQKIGPILDNSTLQSEVKPILEKLTQDQDVDVKYFAQ 579
Query: 251 QAL 243
+AL
Sbjct: 580 EAL 582
Score = 50.4 bits (119), Expect = 4e-06
Identities = 25/98 (25%), Positives = 51/98 (52%)
Frame = -2
Query: 557 MQHIIPQVLEKINNPHYLYRMTILQAISLLAPVMGAEITCQKLLPVVINSSKDRVPNIKF 378
M I+P + E +++ + + + I L+P++G + T + LLP+ + KD P ++
Sbjct: 322 MTQILPCIKELVSDANQHVKSALASVIMGLSPILGKDNTIEHLLPLFLAQLKDECPEVRL 381
Query: 377 NVAKVLQSLVPILDQSVAEKTVKPCLVELSEDPDVDVR 264
N+ L + ++ +++ P +VEL+ED VR
Sbjct: 382 NIISNLDCVNEVIGIRQLSQSLLPAIVELAEDAKWRVR 419
Score = 33.1 bits (74), Expect = 0.66
Identities = 30/137 (21%), Positives = 54/137 (39%), Gaps = 4/137 (2%)
Frame = -2
Query: 548 IIPQVLEKINNPHYLYRMTILQAISLLAPVMGAEITCQKLLPVVINSSKDRVPNIK---- 381
++P + + + + R + + L +G EIT L+P N KD ++
Sbjct: 243 VMPTLRQAAEDKSWRVRYMVADKFTELQKAVGPEITKTDLVPAFQNLMKDCEAEVRAAAS 302
Query: 380 FNVAKVLQSLVPILDQSVAEKTVKPCLVELSEDPDVDVRYYANQALQACDQIMMXXXXXX 201
V + ++L ++V + PC+ EL D + V+ + I+
Sbjct: 303 HKVKEFCENLSADCRENVIMTQILPCIKELVSDANQHVKSALASVIMGLSPIL--GKDNT 360
Query: 200 XCHVL*KLFLVQLWSTC 150
H+L LFL QL C
Sbjct: 361 IEHLL-PLFLAQLKDEC 376
Score = 30.4 bits (67), Expect = 4.2
Identities = 23/124 (18%), Positives = 53/124 (42%)
Frame = -2
Query: 611 AAANNLKRLAXEFGPEWAMQHIIPQVLEKINNPHYLYRMTILQAISLLAPVMGAEITCQK 432
AAA+ L A + IIP ++ R+ ++A +A ++ E
Sbjct: 183 AAASKLGEFAKVLELDNVKSEIIPMFSNLASDEQDSVRLLAVEACVNIAQLLPQEDLEAL 242
Query: 431 LLPVVINSSKDRVPNIKFNVAKVLQSLVPILDQSVAEKTVKPCLVELSEDPDVDVRYYAN 252
++P + +++D+ +++ VA L + + + + P L +D + +VR A+
Sbjct: 243 VMPTLRQAAEDKSWRVRYMVADKFTELQKAVGPEITKTDLVPAFQNLMKDCEAEVRAAAS 302
Query: 251 QALQ 240
++
Sbjct: 303 HKVK 306
Score = 30.0 bits (66), Expect = 5.6
Identities = 17/82 (20%), Positives = 35/82 (42%)
Frame = -2
Query: 506 LYRMTILQAISLLAPVMGAEITCQKLLPVVINSSKDRVPNIKFNVAKVLQSLVPILDQSV 327
+ R + A V+ + +++P+ N + D +++ + ++ +L Q
Sbjct: 179 MVRRAAASKLGEFAKVLELDNVKSEIIPMFSNLASDEQDSVRLLAVEACVNIAQLLPQED 238
Query: 326 AEKTVKPCLVELSEDPDVDVRY 261
E V P L + +ED VRY
Sbjct: 239 LEALVMPTLRQAAEDKSWRVRY 260
>2AAA_HUMAN (P30153) Serine/threonine-protein phosphatase 2A 65 kDa regulatory|
subunit A alpha isoform (PP2A, subunit A, PR65-alpha
isoform) (PP2A, subunit A, R1-alpha isoform) (Medium
tumor antigen-associated 61 kDa protein)
Length = 588
Score = 123 bits (308), Expect = 5e-28
Identities = 61/123 (49%), Positives = 86/123 (69%)
Frame = -2
Query: 611 AAANNLKRLAXEFGPEWAMQHIIPQVLEKINNPHYLYRMTILQAISLLAPVMGAEITCQK 432
AA +NLK+L +FG EWA IIP+VL +P+YL+RMT L I++L+ V G +IT +
Sbjct: 460 AATSNLKKLVEKFGKEWAHATIIPKVLAMSGDPNYLHRMTTLFCINVLSEVCGQDITTKH 519
Query: 431 LLPVVINSSKDRVPNIKFNVAKVLQSLVPILDQSVAEKTVKPCLVELSEDPDVDVRYYAN 252
+LP V+ + D V N++FNVAK LQ + PILD S + VKP L +L++D DVDV+Y+A
Sbjct: 520 MLPTVLRMAGDPVANVRFNVAKSLQKIGPILDNSTLQSEVKPILEKLTQDQDVDVKYFAQ 579
Query: 251 QAL 243
+AL
Sbjct: 580 EAL 582
Score = 50.8 bits (120), Expect = 3e-06
Identities = 25/98 (25%), Positives = 51/98 (52%)
Frame = -2
Query: 557 MQHIIPQVLEKINNPHYLYRMTILQAISLLAPVMGAEITCQKLLPVVINSSKDRVPNIKF 378
M I+P + E +++ + + + I L+P++G + T + LLP+ + KD P ++
Sbjct: 322 MSQILPCIKELVSDANQHVKSALASVIMGLSPILGKDNTIEHLLPLFLAQLKDECPEVRL 381
Query: 377 NVAKVLQSLVPILDQSVAEKTVKPCLVELSEDPDVDVR 264
N+ L + ++ +++ P +VEL+ED VR
Sbjct: 382 NIISNLDCVNEVIGIRQLSQSLLPAIVELAEDAKWRVR 419
Score = 33.9 bits (76), Expect = 0.38
Identities = 30/137 (21%), Positives = 54/137 (39%), Gaps = 4/137 (2%)
Frame = -2
Query: 548 IIPQVLEKINNPHYLYRMTILQAISLLAPVMGAEITCQKLLPVVINSSKDRVPNIK---- 381
++P + + + + R + + L +G EIT L+P N KD ++
Sbjct: 243 VMPTLRQAAEDKSWAVRYMVADKFTELQKAVGPEITKTDLVPAFQNLMKDCEAEVRAAAS 302
Query: 380 FNVAKVLQSLVPILDQSVAEKTVKPCLVELSEDPDVDVRYYANQALQACDQIMMXXXXXX 201
V + ++L ++V + PC+ EL D + V+ + I+
Sbjct: 303 HKVKEFCENLSADCRENVIMSQILPCIKELVSDANQHVKSALASVIMGLSPIL--GKDNT 360
Query: 200 XCHVL*KLFLVQLWSTC 150
H+L LFL QL C
Sbjct: 361 IEHLL-PLFLAQLKDEC 376
Score = 30.0 bits (66), Expect = 5.6
Identities = 17/82 (20%), Positives = 35/82 (42%)
Frame = -2
Query: 506 LYRMTILQAISLLAPVMGAEITCQKLLPVVINSSKDRVPNIKFNVAKVLQSLVPILDQSV 327
+ R + A V+ + +++P+ N + D +++ + ++ +L Q
Sbjct: 179 MVRRAAASKLGEFAKVLELDNVKSEIIPMFSNLASDEQDSVRLLAVEACVNIAQLLPQED 238
Query: 326 AEKTVKPCLVELSEDPDVDVRY 261
E V P L + +ED VRY
Sbjct: 239 LEALVMPTLRQAAEDKSWAVRY 260
Score = 29.6 bits (65), Expect = 7.2
Identities = 23/124 (18%), Positives = 53/124 (42%)
Frame = -2
Query: 611 AAANNLKRLAXEFGPEWAMQHIIPQVLEKINNPHYLYRMTILQAISLLAPVMGAEITCQK 432
AAA+ L A + IIP ++ R+ ++A +A ++ E
Sbjct: 183 AAASKLGEFAKVLELDNVKSEIIPMFSNLASDEQDSVRLLAVEACVNIAQLLPQEDLEAL 242
Query: 431 LLPVVINSSKDRVPNIKFNVAKVLQSLVPILDQSVAEKTVKPCLVELSEDPDVDVRYYAN 252
++P + +++D+ +++ VA L + + + + P L +D + +VR A+
Sbjct: 243 VMPTLRQAAEDKSWAVRYMVADKFTELQKAVGPEITKTDLVPAFQNLMKDCEAEVRAAAS 302
Query: 251 QALQ 240
++
Sbjct: 303 HKVK 306
>2AAA_DROME (P36179) Serine/threonine-protein phosphatase PP2A 65 kDa|
regulatory subunit (Protein phosphatase PP2A regulatory
subunit A) (PR65)
Length = 590
Score = 114 bits (284), Expect = 3e-25
Identities = 58/123 (47%), Positives = 82/123 (66%)
Frame = -2
Query: 611 AAANNLKRLAXEFGPEWAMQHIIPQVLEKINNPHYLYRMTILQAISLLAPVMGAEITCQK 432
AA N+K+L +FG WA Q IIP +L N +YL+RMT L +++LA V G +IT +
Sbjct: 462 AATLNMKKLVEQFGAPWAEQAIIPMILVMSRNKNYLHRMTCLFCLNVLAEVCGTDITTKL 521
Query: 431 LLPVVINSSKDRVPNIKFNVAKVLQSLVPILDQSVAEKTVKPCLVELSEDPDVDVRYYAN 252
LLP V+ + D V N++FNVAK LQ + P L+ SV + VKP L +L+ D DVDV+++A
Sbjct: 522 LLPTVLLLAADPVANVRFNVAKTLQKISPFLEASVIDAQVKPTLDKLNTDTDVDVKHFAA 581
Query: 251 QAL 243
QA+
Sbjct: 582 QAI 584
Score = 52.0 bits (123), Expect = 1e-06
Identities = 26/98 (26%), Positives = 53/98 (54%)
Frame = -2
Query: 557 MQHIIPQVLEKINNPHYLYRMTILQAISLLAPVMGAEITCQKLLPVVINSSKDRVPNIKF 378
+ I+P V + +++P+ + + I L+P++GA T ++LLP+ + KD P ++
Sbjct: 324 LSSILPYVRDLVSDPNPHVKSALASVIMGLSPMLGAYQTVEQLLPLFLIQLKDECPEVRL 383
Query: 377 NVAKVLQSLVPILDQSVAEKTVKPCLVELSEDPDVDVR 264
N+ L + ++ +++ P +VEL+ED VR
Sbjct: 384 NIISNLDCVNDVIGIQQLSQSLLPAIVELAEDSKWRVR 421
Score = 32.0 bits (71), Expect = 1.5
Identities = 23/116 (19%), Positives = 47/116 (40%)
Frame = -2
Query: 611 AAANNLKRLAXEFGPEWAMQHIIPQVLEKINNPHYLYRMTILQAISLLAPVMGAEITCQK 432
AAAN L A E+ +IP ++ + R+ ++A A ++ +
Sbjct: 185 AAANKLGEFAKVVETEYLKSDLIPNFVQLAQDDQDSVRLLAVEACVTSAQLLPQDDVEHL 244
Query: 431 LLPVVINSSKDRVPNIKFNVAKVLQSLVPILDQSVAEKTVKPCLVELSEDPDVDVR 264
+LP + + D +++ VA+ L + + + P L +D + +VR
Sbjct: 245 VLPTLRQCASDSSWRVRYMVAEKFVDLQKAVGPEITRVDLVPAFQYLLKDAEAEVR 300
Score = 29.3 bits (64), Expect = 9.5
Identities = 29/145 (20%), Positives = 59/145 (40%), Gaps = 5/145 (3%)
Frame = -2
Query: 569 PEWAMQHII-PQVLEKINNPHYLYRMTILQAISLLAPVMGAEITCQKLLPVVINSSKDRV 393
P+ ++H++ P + + ++ + R + + L +G EIT L+P KD
Sbjct: 237 PQDDVEHLVLPTLRQCASDSSWRVRYMVAEKFVDLQKAVGPEITRVDLVPAFQYLLKDAE 296
Query: 392 PNIKFNVAKVLQSLVPILDQ----SVAEKTVKPCLVELSEDPDVDVRYYANQALQACDQI 225
++ VA ++ LD+ + ++ P + +L DP+ V+ + +
Sbjct: 297 AEVRAAVATKVKDFCANLDKVNQVQIILSSILPYVRDLVSDPNPHVKSALASVIMGLSPM 356
Query: 224 MMXXXXXXXCHVL*KLFLVQLWSTC 150
+ L LFL+QL C
Sbjct: 357 L---GAYQTVEQLLPLFLIQLKDEC 378
>2AAA_SCHPO (Q9UT08) Protein phosphatase PP2A regulatory subunit A (PR65)|
(Protein phosphatase 2A 65 kDa regulatory subunit)
Length = 590
Score = 110 bits (274), Expect = 4e-24
Identities = 57/128 (44%), Positives = 85/128 (66%), Gaps = 4/128 (3%)
Frame = -2
Query: 611 AAANNLKRLAXEFGPEWAMQHIIPQVLEKINNPHYLYRMTILQAISLLAPVMGAEITCQK 432
AA NL++L FG EWA + IIP+ L ++P+YLYRMT + AIS +AP + AE+ ++
Sbjct: 459 AAIKNLRKLTEIFGLEWATETIIPKFLAMRSHPNYLYRMTTIFAISEIAPALNAEVIEKQ 518
Query: 431 LLPVVINSSKDRVPNIKFNVAKVLQSLVPIL----DQSVAEKTVKPCLVELSEDPDVDVR 264
+LP + D +PNI+FNVAK + L P+L D +V E+ + P L +L++D D DV+
Sbjct: 519 ILPTLEQLVNDPIPNIRFNVAKAFEVLKPVLAAGGDSTVYEQQIIPLLEQLTKDNDPDVQ 578
Query: 263 YYANQALQ 240
Y+A QAL+
Sbjct: 579 YFATQALE 586
Score = 55.8 bits (133), Expect = 9e-08
Identities = 30/98 (30%), Positives = 52/98 (53%)
Frame = -2
Query: 557 MQHIIPQVLEKINNPHYLYRMTILQAISLLAPVMGAEITCQKLLPVVINSSKDRVPNIKF 378
++ IIP + E IN+P R + I LAP +G E T + LLP+ + KD P ++
Sbjct: 321 LEEIIPVIQELINDPAQHVRAALGMNIGALAPQLGKEKTTEYLLPMFLELLKDENPEVRL 380
Query: 377 NVAKVLQSLVPILDQSVAEKTVKPCLVELSEDPDVDVR 264
N+ L+ + ++ + +++ P +V L+ED VR
Sbjct: 381 NIISKLEVVNKVVGIELLSQSLLPAIVTLAEDKQWRVR 418
Score = 31.2 bits (69), Expect = 2.5
Identities = 21/99 (21%), Positives = 44/99 (44%), Gaps = 1/99 (1%)
Frame = -2
Query: 557 MQHIIPQVLEK-INNPHYLYRMTILQAISLLAPVMGAEITCQKLLPVVINSSKDRVPNIK 381
++H + Q L +++ + R + LA V+G + +L+ + KD ++
Sbjct: 242 IRHYLLQPLRSFVSDSSWRTRYMVAANFVKLAKVVGPSLIKDELIKPFVLLMKDTEQEVR 301
Query: 380 FNVAKVLQSLVPILDQSVAEKTVKPCLVELSEDPDVDVR 264
+A + +LD+ + + + P + EL DP VR
Sbjct: 302 RAIATQIPGFCELLDKRIVLEEIIPVIQELINDPAQHVR 340
>2AAA_CAEEL (Q09543) Probable serine/threonine-protein phosphatase PP2A|
regulatory subunit (Protein phosphatase PP2A regulatory
subunit A)
Length = 590
Score = 84.7 bits (208), Expect = 2e-16
Identities = 42/117 (35%), Positives = 71/117 (60%)
Frame = -2
Query: 596 LKRLAXEFGPEWAMQHIIPQVLEKINNPHYLYRMTILQAISLLAPVMGAEITCQKLLPVV 417
+K L +FG +WA +I+P++ + + +YL RMT L ++ L+ M E ++++P+V
Sbjct: 468 MKELTQKFGGQWASTNIVPKMQKLQKDTNYLQRMTCLFCLNTLSEAMTQEQILKEIMPIV 527
Query: 416 INSSKDRVPNIKFNVAKVLQSLVPILDQSVAEKTVKPCLVELSEDPDVDVRYYANQA 246
+ +D VPN++FN AK L+ + L S VKP L +L +D D DVRY++ +A
Sbjct: 528 KDLVEDDVPNVRFNAAKSLKRIGKNLTPSTLTSEVKPLLEKLGKDSDFDVRYFSEEA 584
Score = 47.0 bits (110), Expect = 4e-05
Identities = 33/121 (27%), Positives = 57/121 (47%), Gaps = 5/121 (4%)
Frame = -2
Query: 611 AAANNLKRLAXEFGPEWAMQHIIPQVL-----EKINNPHYLYRMTILQAISLLAPVMGAE 447
AA L+ A PE Q+II L E + + + L + + I LAP++G E
Sbjct: 303 AATQRLQEFALNL-PEDKRQNIICNSLLNVAKELVTDGNQLVKSELAGVIMGLAPLIGKE 361
Query: 446 ITCQKLLPVVINSSKDRVPNIKFNVAKVLQSLVPILDQSVAEKTVKPCLVELSEDPDVDV 267
T +LLP+ + D+ P ++ N+ L + ++ + ++ P +V L+ED V
Sbjct: 362 QTVSELLPIYMQLLNDQTPEVRLNIISSLDKVNEVIGAAQLSTSLLPAIVGLAEDGKWRV 421
Query: 266 R 264
R
Sbjct: 422 R 422
Score = 37.7 bits (86), Expect = 0.027
Identities = 24/107 (22%), Positives = 50/107 (46%)
Frame = -2
Query: 602 NNLKRLAXEFGPEWAMQHIIPQVLEKINNPHYLYRMTILQAISLLAPVMGAEITCQKLLP 423
++L ++ G ++P ++ + + R+ I+Q + LLA +G E +KLLP
Sbjct: 388 SSLDKVNEVIGAAQLSTSLLPAIVGLAEDGKWRVRLAIVQFMPLLASQLGQEFFDEKLLP 447
Query: 422 VVINSSKDRVPNIKFNVAKVLQSLVPILDQSVAEKTVKPCLVELSED 282
+ +N D V +I+ +++ L A + P + +L +D
Sbjct: 448 LCLNWLTDHVFSIREASTLIMKELTQKFGGQWASTNIVPKMQKLQKD 494
>DNAA_RHOPA (Q6NDV3) Chromosomal replication initiator protein dnaA|
Length = 472
Score = 29.3 bits (64), Expect = 9.5
Identities = 11/44 (25%), Positives = 22/44 (50%)
Frame = +3
Query: 270 IHIRVLAELDEAWFHSLFSDRLIKDWHKRLKNFRDIELDVRHSV 401
+H+ V ++W + +SD+++ W L ++L VR V
Sbjct: 42 VHLSVPTRFLKSWIQTHYSDKVLSCWQAELPEVNRVDLTVRSPV 85
Database: uniprot_sprot.fasta
Posted date: May 25, 2006 5:36 PM
Number of letters in database: 80,573,946
Number of sequences in database: 219,361
Lambda K H
0.318 0.135 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 91,386,298
Number of Sequences: 219361
Number of extensions: 1888450
Number of successful extensions: 4759
Number of sequences better than 10.0: 28
Number of HSP's better than 10.0 without gapping: 4515
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4747
length of database: 80,573,946
effective HSP length: 107
effective length of database: 57,102,319
effective search space used: 5481822624
frameshift window, decay const: 50, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)