ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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| Clone Name | rbasd22k21 |
|---|---|
| Clone Library Name | barley_pub |
>RLCK7_ARATH (Q9LQQ8) Probable serine/threonine-protein kinase RLCKVII (EC| 2.7.11.1) Length = 423 Score = 101 bits (251), Expect = 2e-21 Identities = 49/95 (51%), Positives = 65/95 (68%) Frame = -3 Query: 648 QYTMKSDVYSFGVVMLELLTGRKPFDSSKPRSEQSLVRWASPQLHDIDALDRMVDPALKG 469 Q T KSD+YSFGVV+LEL+TGRK D++K R +Q+LV WA P D +MVDP L+G Sbjct: 283 QLTFKSDIYSFGVVLLELITGRKAIDNTKTRKDQNLVGWARPLFKDRRNFPKMVDPLLQG 342 Query: 468 LYPAKSLSRFADVLALCVQAEPEFRPPMSEVVQAL 364 YP + L + + A+CVQ +P RP +S+VV AL Sbjct: 343 QYPVRGLYQALAISAMCVQEQPTMRPVVSDVVLAL 377
>PBS1_ARATH (Q9FE20) Serine/threonine-protein kinase PBS1 (EC 2.7.11.1)| (AvrPphB susceptible protein 1) Length = 456 Score = 99.8 bits (247), Expect = 6e-21 Identities = 54/120 (45%), Positives = 73/120 (60%) Frame = -3 Query: 648 QYTMKSDVYSFGVVMLELLTGRKPFDSSKPRSEQSLVRWASPQLHDIDALDRMVDPALKG 469 Q T+KSDVYSFGVV LEL+TGRK DS P EQ+LV WA P +D ++ DP LKG Sbjct: 266 QLTVKSDVYSFGVVFLELITGRKAIDSEMPHGEQNLVAWARPLFNDRRKFIKLADPRLKG 325 Query: 468 LYPAKSLSRFADVLALCVQAEPEFRPPMSEVVQALVRLVQRANMTKKMLDGDASRRGDDQ 289 +P ++L + V ++C+Q + RP +++VV AL L +A K D SRR D+ Sbjct: 326 RFPTRALYQALAVASMCIQEQAATRPLIADVVTALSYLANQAYDPSK----DDSRRNRDE 381
>NORK_PEA (Q8LKZ1) Nodulation receptor kinase precursor (EC 2.7.11.1)| Length = 924 Score = 83.6 bits (205), Expect = 5e-16 Identities = 41/95 (43%), Positives = 63/95 (66%) Frame = -3 Query: 648 QYTMKSDVYSFGVVMLELLTGRKPFDSSKPRSEQSLVRWASPQLHDIDALDRMVDPALKG 469 Q + KSDV+SFGVV+LE+++GR+P + +PR E SLV WA P + +D +VDP +KG Sbjct: 774 QLSEKSDVFSFGVVLLEIVSGREPLNIKRPRVEWSLVEWAKPYIR-ASKVDEIVDPGIKG 832 Query: 468 LYPAKSLSRFADVLALCVQAEPEFRPPMSEVVQAL 364 Y A++L R +V C++ +RP M ++V+ L Sbjct: 833 GYHAEALWRVVEVALQCLEPYSTYRPCMVDIVREL 867
>NORK_MEDTR (Q8L4H4) Nodulation receptor kinase precursor (EC 2.7.11.1) (Does not| make infections protein 2) (Symbiosis receptor-like kinase) (MtSYMRK) Length = 925 Score = 83.6 bits (205), Expect = 5e-16 Identities = 41/95 (43%), Positives = 63/95 (66%) Frame = -3 Query: 648 QYTMKSDVYSFGVVMLELLTGRKPFDSSKPRSEQSLVRWASPQLHDIDALDRMVDPALKG 469 Q + KSDV+SFGVV+LE+++GR+P + +PR E SLV WA P + +D +VDP +KG Sbjct: 775 QLSEKSDVFSFGVVLLEIVSGREPLNIKRPRIEWSLVEWAKPYIR-ASKVDEIVDPGIKG 833 Query: 468 LYPAKSLSRFADVLALCVQAEPEFRPPMSEVVQAL 364 Y A++L R +V C++ +RP M ++V+ L Sbjct: 834 GYHAEALWRVVEVALQCLEPYSTYRPCMVDIVREL 868
>NAK_ARATH (P43293) Probable serine/threonine-protein kinase NAK (EC 2.7.11.1)| Length = 389 Score = 80.1 bits (196), Expect = 5e-15 Identities = 40/96 (41%), Positives = 61/96 (63%) Frame = -3 Query: 642 TMKSDVYSFGVVMLELLTGRKPFDSSKPRSEQSLVRWASPQLHDIDALDRMVDPALKGLY 463 ++KSDVYSFGVV+LELL+GR+ D ++P E +LV WA P L + L R++DP L+G Y Sbjct: 258 SVKSDVYSFGVVLLELLSGRRAIDKNQPVGEHNLVDWARPYLTNKRRLLRVMDPRLQGQY 317 Query: 462 PAKSLSRFADVLALCVQAEPEFRPPMSEVVQALVRL 355 + A + C+ + + RP M+E+V+ + L Sbjct: 318 SLTRALKIAVLALDCISIDAKSRPTMNEIVKTMEEL 353
>CX32_ARATH (P27450) Probable serine/threonine-protein kinase Cx32, chloroplast| precursor (EC 2.7.11.1) Length = 419 Score = 79.7 bits (195), Expect = 7e-15 Identities = 35/92 (38%), Positives = 60/92 (65%) Frame = -3 Query: 639 MKSDVYSFGVVMLELLTGRKPFDSSKPRSEQSLVRWASPQLHDIDALDRMVDPALKGLYP 460 +KSDV++FGVV+LE++TG ++ +PR ++SLV W P+L + + +++D +KG Y Sbjct: 274 VKSDVFAFGVVLLEIMTGLTAHNTKRPRGQESLVDWLRPELSNKHRVKQIMDKGIKGQYT 333 Query: 459 AKSLSRFADVLALCVQAEPEFRPPMSEVVQAL 364 K + A + C++ +P+ RP M EVV+ L Sbjct: 334 TKVATEMARITLSCIEPDPKNRPHMKEVVEVL 365
>APK1A_ARATH (Q06548) Protein kinase APK1A, chloroplast precursor (EC 2.7.11.1)| Length = 410 Score = 79.7 bits (195), Expect = 7e-15 Identities = 41/93 (44%), Positives = 58/93 (62%) Frame = -3 Query: 642 TMKSDVYSFGVVMLELLTGRKPFDSSKPRSEQSLVRWASPQLHDIDALDRMVDPALKGLY 463 T KSDVYSFGVV+LELL+GR+ D ++P E++LV WA P L + + R++D L+ Y Sbjct: 258 TTKSDVYSFGVVLLELLSGRRAVDKNRPSGERNLVEWAKPYLVNKRKIFRVIDNRLQDQY 317 Query: 462 PAKSLSRFADVLALCVQAEPEFRPPMSEVVQAL 364 + + A + C+ E + RP MSEVV L Sbjct: 318 SMEEACKVATLSLRCLTTEIKLRPNMSEVVSHL 350
>APK1B_ARATH (P46573) Protein kinase APK1B, chloroplast precursor (EC 2.7.11.1)| Length = 412 Score = 77.0 bits (188), Expect = 4e-14 Identities = 40/93 (43%), Positives = 57/93 (61%) Frame = -3 Query: 642 TMKSDVYSFGVVMLELLTGRKPFDSSKPRSEQSLVRWASPQLHDIDALDRMVDPALKGLY 463 T KSDVYS+GVV+LE+L+GR+ D ++P EQ LV WA P L + L R++D L+ Y Sbjct: 259 TTKSDVYSYGVVLLEVLSGRRAVDKNRPPGEQKLVEWARPLLANKRKLFRVIDNRLQDQY 318 Query: 462 PAKSLSRFADVLALCVQAEPEFRPPMSEVVQAL 364 + + A + C+ E + RP M+EVV L Sbjct: 319 SMEEACKVATLALRCLTFEIKLRPNMNEVVSHL 351
>PSKR_ARATH (Q9ZVR7) Putative phytosulfokine receptor precursor (EC 2.7.11.1)| (Phytosulfokine LRR receptor kinase) Length = 1008 Score = 66.2 bits (160), Expect = 8e-11 Identities = 34/93 (36%), Positives = 50/93 (53%) Frame = -3 Query: 642 TMKSDVYSFGVVMLELLTGRKPFDSSKPRSEQSLVRWASPQLHDIDALDRMVDPALKGLY 463 T K DVYSFGVV+LELLT ++P D KP+ + L+ W H+ A + DP + Sbjct: 914 TYKGDVYSFGVVLLELLTDKRPVDMCKPKGCRDLISWVVKMKHESRA-SEVFDPLIYSKE 972 Query: 462 PAKSLSRFADVLALCVQAEPEFRPPMSEVVQAL 364 K + R ++ LC+ P+ RP ++V L Sbjct: 973 NDKEMFRVLEIACLCLSENPKQRPTTQQLVSWL 1005
>PSKR_DAUCA (Q8LPB4) Phytosulfokine receptor precursor (EC 2.7.11.1)| (Phytosulfokine LRR receptor kinase) Length = 1021 Score = 63.2 bits (152), Expect = 7e-10 Identities = 34/93 (36%), Positives = 49/93 (52%) Frame = -3 Query: 642 TMKSDVYSFGVVMLELLTGRKPFDSSKPRSEQSLVRWASPQLHDIDALDRMVDPALKGLY 463 T K DVYSFGVV+LELLTGR+P D KPR + L+ W Q+ + DP + Sbjct: 923 TYKGDVYSFGVVLLELLTGRRPMDVCKPRGSRDLISWVL-QMKTEKRESEIFDPFIYDKD 981 Query: 462 PAKSLSRFADVLALCVQAEPEFRPPMSEVVQAL 364 A+ + ++ C+ P+ RP ++V L Sbjct: 982 HAEEMLLVLEIACRCLGENPKTRPTTQQLVSWL 1014
>EXS_ARATH (Q9LYN8) Leucine-rich repeat receptor protein kinase EXS precursor| (EC 2.7.11.1) (Extra sporogenous cells protein) (EXCESS MICROSPOROCYTES1 protein) Length = 1192 Score = 62.8 bits (151), Expect = 9e-10 Identities = 37/94 (39%), Positives = 55/94 (58%), Gaps = 1/94 (1%) Frame = -3 Query: 642 TMKSDVYSFGVVMLELLTGRKPFDSSKPRSE-QSLVRWASPQLHDIDALDRMVDPALKGL 466 T K DVYSFGV++LEL+TG++P SE +LV WA +++ A+D ++DP L + Sbjct: 1097 TTKGDVYSFGVILLELVTGKEPTGPDFKESEGGNLVGWAIQKINQGKAVD-VIDPLLVSV 1155 Query: 465 YPAKSLSRFADVLALCVQAEPEFRPPMSEVVQAL 364 S R + LC+ P RP M +V++AL Sbjct: 1156 ALKNSQLRLLQIAMLCLAETPAKRPNMLDVLKAL 1189
>CRI4_MAIZE (O24585) Putative receptor protein kinase CRINKLY4 precursor (EC| 2.7.11.1) Length = 901 Score = 62.8 bits (151), Expect = 9e-10 Identities = 38/93 (40%), Positives = 53/93 (56%) Frame = -3 Query: 642 TMKSDVYSFGVVMLELLTGRKPFDSSKPRSEQSLVRWASPQLHDIDALDRMVDPALKGLY 463 T KSDVYSFGVV+LE+L+GRK D E ++V WA P + D + ++DP L Sbjct: 689 TTKSDVYSFGVVLLEILSGRKAIDMQ--FEEGNIVEWAVPLIKAGD-IFAILDPVLSPPS 745 Query: 462 PAKSLSRFADVLALCVQAEPEFRPPMSEVVQAL 364 ++L + A V CV+ + RP M +V AL Sbjct: 746 DLEALKKIASVACKCVRMRGKDRPSMDKVTTAL 778
>BAK1_ARATH (Q94F62) BRASSINOSTEROID INSENSITIVE 1-associated receptor kinase 1| precursor (EC 2.7.11.1) (BRI1-associated receptor kinase 1) (Somatic embryogenesis receptor-like kinase 3) Length = 615 Score = 62.4 bits (150), Expect = 1e-09 Identities = 34/93 (36%), Positives = 56/93 (60%), Gaps = 2/93 (2%) Frame = -3 Query: 636 KSDVYSFGVVMLELLTGRKPFDSSKPRSEQS--LVRWASPQLHDIDALDRMVDPALKGLY 463 K+DV+ +GV++LEL+TG++ FD ++ ++ L+ W L + L+ +VD L+G Y Sbjct: 472 KTDVFGYGVMLLELITGQRAFDLARLANDDDVMLLDWVKGLLKE-KKLEALVDVDLQGNY 530 Query: 462 PAKSLSRFADVLALCVQAEPEFRPPMSEVVQAL 364 + + + V LC Q+ P RP MSEVV+ L Sbjct: 531 KDEEVEQLIQVALLCTQSSPMERPKMSEVVRML 563
>CLV1_ARATH (Q9SYQ8) Receptor protein kinase CLAVATA1 precursor (EC 2.7.11.1)| Length = 980 Score = 59.3 bits (142), Expect = 1e-08 Identities = 39/97 (40%), Positives = 50/97 (51%), Gaps = 6/97 (6%) Frame = -3 Query: 636 KSDVYSFGVVMLELLTGRKPFDSSKPRSEQSLVRWAS------PQLHDIDALDRMVDPAL 475 KSDVYSFGVV+LEL+ G+KP + +VRW Q D + +VDP L Sbjct: 874 KSDVYSFGVVLLELIAGKKPVGEFGEGVD--IVRWVRNTEEEITQPSDAAIVVAIVDPRL 931 Query: 474 KGLYPAKSLSRFADVLALCVQAEPEFRPPMSEVVQAL 364 G YP S+ + +CV+ E RP M EVV L Sbjct: 932 TG-YPLTSVIHVFKIAMMCVEEEAAARPTMREVVHML 967
>TMK1_ARATH (P43298) Putative receptor protein kinase TMK1 precursor (EC| 2.7.11.1) Length = 942 Score = 57.4 bits (137), Expect = 4e-08 Identities = 37/103 (35%), Positives = 51/103 (49%), Gaps = 5/103 (4%) Frame = -3 Query: 642 TMKSDVYSFGVVMLELLTGRKPFDSSKPRSEQSLVRW-----ASPQLHDIDALDRMVDPA 478 T K DVYSFGV+++EL+TGRK D S+P LV W + + A+D +D Sbjct: 771 TTKVDVYSFGVILMELITGRKSLDESQPEESIHLVSWFKRMYINKEASFKKAIDTTIDLD 830 Query: 477 LKGLYPAKSLSRFADVLALCVQAEPEFRPPMSEVVQALVRLVQ 349 + L S+ A++ C EP RP M V L LV+ Sbjct: 831 EETL---ASVHTVAELAGHCCAREPYQRPDMGHAVNILSSLVE 870
>BRL3_ARATH (Q9LJF3) Serine/threonine-protein kinase BRI1-like 3 precursor (EC| 2.7.11.1) (BRASSINOSTEROID INSENSITIVE 1-like protein 3) Length = 1164 Score = 55.8 bits (133), Expect = 1e-07 Identities = 35/99 (35%), Positives = 52/99 (52%), Gaps = 1/99 (1%) Frame = -3 Query: 642 TMKSDVYSFGVVMLELLTGRKPFDSSKPRSEQSLVRWASPQLHDIDALDRMVDPAL-KGL 466 T K DVYS+GV++LELL+G+KP D + + +LV WA QL+ ++DP L Sbjct: 1040 TAKGDVYSYGVILLELLSGKKPIDPEEFGEDNNLVGWAK-QLYREKRGAEILDPELVTDK 1098 Query: 465 YPAKSLSRFADVLALCVQAEPEFRPPMSEVVQALVRLVQ 349 L + + + C+ P RP M +V+ LVQ Sbjct: 1099 SGDVELLHYLKIASQCLDDRPFKRPTMIQVMTMFKELVQ 1137
>RLK5_ARATH (P47735) Receptor-like protein kinase 5 precursor (EC 2.7.11.1)| Length = 999 Score = 55.5 bits (132), Expect = 1e-07 Identities = 34/88 (38%), Positives = 51/88 (57%) Frame = -3 Query: 636 KSDVYSFGVVMLELLTGRKPFDSSKPRSEQSLVRWASPQLHDIDALDRMVDPALKGLYPA 457 KSD+YSFGVV+LEL+TG++P DS ++ + +W L D L+ ++DP L L Sbjct: 878 KSDIYSFGVVLLELVTGKQPTDSE--LGDKDMAKWVCTAL-DKCGLEPVIDPKL-DLKFK 933 Query: 456 KSLSRFADVLALCVQAEPEFRPPMSEVV 373 + +S+ + LC P RP M +VV Sbjct: 934 EEISKVIHIGLLCTSPLPLNRPSMRKVV 961
>RPK1_IPONI (P93194) Receptor-like protein kinase precursor (EC 2.7.11.1)| Length = 1109 Score = 54.3 bits (129), Expect = 3e-07 Identities = 34/97 (35%), Positives = 53/97 (54%), Gaps = 4/97 (4%) Frame = -3 Query: 636 KSDVYSFGVVMLELLTGRKPFDSSKPRSEQSLVRWASPQLHDIDALDRMVDPA-LKGLYP 460 +SDVYS+GVV+LEL+T +K D S E +V W + ++VDP+ L L Sbjct: 999 ESDVYSYGVVLLELITRKKALDPSF-NGETDIVGWVRSVWTQTGEIQKIVDPSLLDELID 1057 Query: 459 AKSLSRFADVLAL---CVQAEPEFRPPMSEVVQALVR 358 + + + + L+L C + E + RP M +VV+ L R Sbjct: 1058 SSVMEQVTEALSLALRCAEKEVDKRPTMRDVVKQLTR 1094
>BRL1_ARATH (Q9ZWC8) Serine/threonine-protein kinase BRI1-like 1 precursor (EC| 2.7.11.1) (BRASSINOSTEROID INSENSITIVE 1-like protein 1) Length = 1166 Score = 51.2 bits (121), Expect = 3e-06 Identities = 31/91 (34%), Positives = 49/91 (53%), Gaps = 1/91 (1%) Frame = -3 Query: 642 TMKSDVYSFGVVMLELLTGRKPFDSSKPRSEQSLVRWASPQLHDIDALDRMVDPAL-KGL 466 T K DVYS+GV++LELL+G+KP D + + +LV WA QL+ ++DP L Sbjct: 1042 TAKGDVYSYGVILLELLSGKKPIDPGEFGEDNNLVGWAK-QLYREKRGAEILDPELVTDK 1100 Query: 465 YPAKSLSRFADVLALCVQAEPEFRPPMSEVV 373 L + + + C+ P RP M +++ Sbjct: 1101 SGDVELFHYLKIASQCLDDRPFKRPTMIQLM 1131
>BRL2_ARATH (Q9ZPS9) Serine/threonine-protein kinase BRI1-like 2 precursor (EC| 2.7.11.1) (BRASSINOSTEROID INSENSITIVE 1-like protein 2) (Protein VASCULAR HIGHWAY 1) Length = 1143 Score = 50.4 bits (119), Expect = 4e-06 Identities = 34/110 (30%), Positives = 54/110 (49%), Gaps = 14/110 (12%) Frame = -3 Query: 642 TMKSDVYSFGVVMLELLTGRKPFDSSKPRSEQSLVRWASPQLHDIDALDRMVDPALK--- 472 T K DVYS GVVMLE+L+G++P D + + +LV W+ + + ++ + + LK Sbjct: 1021 TAKGDVYSIGVVMLEILSGKRPTDKEE-FGDTNLVGWSKMKAREGKHMEVIDEDLLKEGS 1079 Query: 471 -----------GLYPAKSLSRFADVLALCVQAEPEFRPPMSEVVQALVRL 355 G K + R+ ++ CV P RP M +VV +L L Sbjct: 1080 SESLNEKEGFEGGVIVKEMLRYLEIALRCVDDFPSKRPNMLQVVASLREL 1129
>SIRK_ARATH (O64483) Senescence-induced receptor-like serine/threonine-protein| kinase precursor (FLG22-induced receptor-like kinase 1) Length = 876 Score = 48.5 bits (114), Expect = 2e-05 Identities = 34/102 (33%), Positives = 50/102 (49%), Gaps = 3/102 (2%) Frame = -3 Query: 648 QYTMKSDVYSFGVVMLELLTGRKPFDSSKPRSEQSLVRWASPQLHDIDA---LDRMVDPA 478 Q KSDVYS GVV+LE++TG+ SSK S + I A + +VD Sbjct: 750 QMNEKSDVYSLGVVLLEVITGQPAIASSKTEKVH-----ISDHVRSILANGDIRGIVDQR 804 Query: 477 LKGLYPAKSLSRFADVLALCVQAEPEFRPPMSEVVQALVRLV 352 L+ Y S + +++ C + RP MS+VV L ++V Sbjct: 805 LRERYDVGSAWKMSEIALACTEHTSAQRPTMSQVVMELKQIV 846
>YR831_MIMIV (Q7T6Y2) Putative serine/threonine-protein kinase/receptor R831| precursor (EC 2.7.11.1) Length = 1624 Score = 48.1 bits (113), Expect = 2e-05 Identities = 32/101 (31%), Positives = 56/101 (55%) Frame = -3 Query: 648 QYTMKSDVYSFGVVMLELLTGRKPFDSSKPRSEQSLVRWASPQLHDIDALDRMVDPALKG 469 +Y K+DV+SFGVVM E+LTG++PF +E + ++ + +D L+ + Sbjct: 1536 KYCEKADVFSFGVVMWEVLTGKEPF------AECNFMKVS------LDILE-----GGRP 1578 Query: 468 LYPAKSLSRFADVLALCVQAEPEFRPPMSEVVQALVRLVQR 346 + P+ FA ++ C A+ RP M+EVVQ L+ + ++ Sbjct: 1579 IIPSDCPHEFAKLIKKCWHAKAHKRPTMTEVVQQLMLITEQ 1619 Score = 37.4 bits (85), Expect = 0.039 Identities = 30/114 (26%), Positives = 50/114 (43%), Gaps = 2/114 (1%) Frame = -3 Query: 633 SDVYSFGVVMLELLTGRKPFDSSKPRS-EQSLVRWASPQLHDIDALDRMVDPALKGLYPA 457 +DVYSFG+++ ELLT +P+ P + S++R D M P A Sbjct: 968 ADVYSFGIILWELLTREQPYKGMTPAAIAVSVIR------------DGMRPPISDEAVTA 1015 Query: 456 KSLSRFADVLALCVQAEPEFRPPMSEVVQALVRLV-QRANMTKKMLDGDASRRG 298 S+ + D++ C ++ RP E++ L ++ +NMT S G Sbjct: 1016 HSI-EYIDLIKQCWHSDTIIRPTFLEIMTRLSNILGDSSNMTSGTSSSSLSSGG 1068
>BRI1_ARATH (O22476) BRASSINOSTEROID INSENSITIVE 1 precursor (EC 2.7.11.1)| (AtBRI1) (Brassinosteroid LRR receptor kinase) Length = 1196 Score = 45.4 bits (106), Expect = 1e-04 Identities = 33/90 (36%), Positives = 46/90 (51%), Gaps = 2/90 (2%) Frame = -3 Query: 636 KSDVYSFGVVMLELLTGRKPFDSSKPRSEQSLVRWASPQLHDIDALDRMVDPALKGLYPA 457 K DVYS+GVV+LELLTG++P D S + +LV W + H + + DP L PA Sbjct: 1066 KGDVYSYGVVLLELLTGKRPTD-SPDFGDNNLVGWV--KQHAKLRISDVFDPELMKEDPA 1122 Query: 456 K--SLSRFADVLALCVQAEPEFRPPMSEVV 373 L + V C+ RP M +V+ Sbjct: 1123 LEIELLQHLKVAVACLDDRAWRRPTMVQVM 1152
>TMKL1_ARATH (P33543) Putative kinase-like protein TMKL1 precursor| Length = 674 Score = 45.4 bits (106), Expect = 1e-04 Identities = 33/100 (33%), Positives = 53/100 (53%), Gaps = 9/100 (9%) Frame = -3 Query: 636 KSDVYSFGVVMLELLTGRKPFDSSKPRSE----QSLVRWA-----SPQLHDIDALDRMVD 484 +SDVY+FG+++LE+L G+KP S + +E SLV+ A + ++ D++A+ + Sbjct: 556 RSDVYAFGILLLEILMGKKPGKSGRNGNEFVDLPSLVKAAVLEETTMEVFDLEAMKGIRS 615 Query: 483 PALKGLYPAKSLSRFADVLALCVQAEPEFRPPMSEVVQAL 364 P +GL A L+ C RP M EVV+ L Sbjct: 616 PMEEGLVHALKLAMG------CCAPVTTVRPSMEEVVKQL 649
>SRK6_BRAOE (Q09092) Putative serine/threonine-protein kinase receptor| precursor (EC 2.7.11.1) (S-receptor kinase) (SRK) Length = 849 Score = 45.4 bits (106), Expect = 1e-04 Identities = 30/98 (30%), Positives = 52/98 (53%), Gaps = 7/98 (7%) Frame = -3 Query: 645 YTMKSDVYSFGVVMLELLTGRKPFDSSKPRSEQSLVRWASPQLHDIDALDRMVDPAL--- 475 ++ KSDV+SFGV++LE+++G+K E L+ + + + AL+ +VDP + Sbjct: 707 FSEKSDVFSFGVIVLEIVSGKKNRGFYNLDYENDLLSYVWSRWKEGRALE-IVDPVIVDS 765 Query: 474 ----KGLYPAKSLSRFADVLALCVQAEPEFRPPMSEVV 373 ++ + + + + LCVQ E RP MS VV Sbjct: 766 LSSQPSIFQPQEVLKCIQIGLLCVQELAEHRPAMSSVV 803
>OXSR1_PONPY (Q5R495) Serine/threonine-protein kinase OSR1 (EC 2.7.11.1)| (Oxidative stress-responsive 1 protein) Length = 527 Score = 44.7 bits (104), Expect = 2e-04 Identities = 27/92 (29%), Positives = 45/92 (48%) Frame = -3 Query: 645 YTMKSDVYSFGVVMLELLTGRKPFDSSKPRSEQSLVRWASPQLHDIDALDRMVDPALKGL 466 Y K+D++SFG+ +EL TG P+ P L P + D+ + LK Sbjct: 204 YDFKADIWSFGITAIELATGAAPYHKYPPMKVLMLTLQNDPPSLETGVQDKEM---LK-- 258 Query: 465 YPAKSLSRFADVLALCVQAEPEFRPPMSEVVQ 370 K F +++LC+Q +PE RP +E+++ Sbjct: 259 ---KYGKSFRKMISLCLQKDPEKRPTAAELLR 287
>OXSR1_MOUSE (Q6P9R2) Serine/threonine-protein kinase OSR1 (EC 2.7.11.1)| (Oxidative stress-responsive 1 protein) Length = 527 Score = 44.7 bits (104), Expect = 2e-04 Identities = 27/92 (29%), Positives = 45/92 (48%) Frame = -3 Query: 645 YTMKSDVYSFGVVMLELLTGRKPFDSSKPRSEQSLVRWASPQLHDIDALDRMVDPALKGL 466 Y K+D++SFG+ +EL TG P+ P L P + D+ + LK Sbjct: 204 YDFKADIWSFGITAIELATGAAPYHKYPPMKVLMLTLQNDPPSLETGVQDKEM---LK-- 258 Query: 465 YPAKSLSRFADVLALCVQAEPEFRPPMSEVVQ 370 K F +++LC+Q +PE RP +E+++ Sbjct: 259 ---KYGKSFRKMISLCLQKDPEKRPTAAELLR 287
>OXSR1_HUMAN (O95747) Serine/threonine-protein kinase OSR1 (EC 2.7.11.1)| (Oxidative stress-responsive 1 protein) Length = 527 Score = 44.7 bits (104), Expect = 2e-04 Identities = 27/92 (29%), Positives = 45/92 (48%) Frame = -3 Query: 645 YTMKSDVYSFGVVMLELLTGRKPFDSSKPRSEQSLVRWASPQLHDIDALDRMVDPALKGL 466 Y K+D++SFG+ +EL TG P+ P L P + D+ + LK Sbjct: 204 YDFKADIWSFGITAIELATGAAPYHKYPPMKVLMLTLQNDPPSLETGVQDKEM---LK-- 258 Query: 465 YPAKSLSRFADVLALCVQAEPEFRPPMSEVVQ 370 K F +++LC+Q +PE RP +E+++ Sbjct: 259 ---KYGKSFRKMISLCLQKDPEKRPTAAELLR 287
>OXSR1_PIG (Q863I2) Serine/threonine-protein kinase OSR1 (EC 2.7.11.1)| (Oxidative stress-responsive 1 protein) Length = 529 Score = 44.7 bits (104), Expect = 2e-04 Identities = 27/92 (29%), Positives = 45/92 (48%) Frame = -3 Query: 645 YTMKSDVYSFGVVMLELLTGRKPFDSSKPRSEQSLVRWASPQLHDIDALDRMVDPALKGL 466 Y K+D++SFG+ +EL TG P+ P L P + D+ + LK Sbjct: 204 YDFKADIWSFGITAIELATGAAPYHKYPPMKVLMLTLQNDPPSLETGVQDKEM---LK-- 258 Query: 465 YPAKSLSRFADVLALCVQAEPEFRPPMSEVVQ 370 K F +++LC+Q +PE RP +E+++ Sbjct: 259 ---KYGKSFRKMISLCLQKDPEKRPTAAELLR 287
>STK39_MOUSE (Q9Z1W9) STE20/SPS1-related proline-alanine-rich protein kinase (EC| 2.7.11.1) (Ste-20-related kinase) (Serine/threonine-protein kinase 39) Length = 556 Score = 43.5 bits (101), Expect = 5e-04 Identities = 29/117 (24%), Positives = 53/117 (45%) Frame = -3 Query: 645 YTMKSDVYSFGVVMLELLTGRKPFDSSKPRSEQSLVRWASPQLHDIDALDRMVDPALKGL 466 Y K+D++SFG+ +EL TG P+ P L P + D+ + Sbjct: 262 YDFKADMWSFGITAIELATGAAPYHKYPPMKVLMLTLQNDPPTLETGVEDKEM------- 314 Query: 465 YPAKSLSRFADVLALCVQAEPEFRPPMSEVVQALVRLVQRANMTKKMLDGDASRRGD 295 K F +L+LC+Q +P RP +E+++ + Q+A + +++ +R D Sbjct: 315 -MKKYGKSFRKLLSLCLQKDPSKRPTAAELLKC--KFFQKAKNREYLIEKLLTRTPD 368
>STK39_HUMAN (Q9UEW8) STE20/SPS1-related proline-alanine-rich protein kinase (EC| 2.7.11.1) (Ste-20-related kinase) (Serine/threonine-protein kinase 39) (DCHT) Length = 547 Score = 43.5 bits (101), Expect = 5e-04 Identities = 29/117 (24%), Positives = 53/117 (45%) Frame = -3 Query: 645 YTMKSDVYSFGVVMLELLTGRKPFDSSKPRSEQSLVRWASPQLHDIDALDRMVDPALKGL 466 Y K+D++SFG+ +EL TG P+ P L P + D+ + Sbjct: 252 YDFKADMWSFGITAIELATGAAPYHKYPPMKVLMLTLQNDPPTLETGVEDKEM------- 304 Query: 465 YPAKSLSRFADVLALCVQAEPEFRPPMSEVVQALVRLVQRANMTKKMLDGDASRRGD 295 K F +L+LC+Q +P RP +E+++ + Q+A + +++ +R D Sbjct: 305 -MKKYGKSFRKLLSLCLQKDPSKRPTAAELLKC--KFFQKAKNREYLIEKLLTRTPD 358
>STK39_RAT (O88506) STE20/SPS1-related proline-alanine-rich protein kinase (EC| 2.7.11.1) (Ste-20-related kinase) (Serine/threonine-protein kinase 39) (Pancreatic serine/threonine-protein kinase) (PS/TK) (PSTK1) Length = 553 Score = 43.5 bits (101), Expect = 5e-04 Identities = 29/117 (24%), Positives = 53/117 (45%) Frame = -3 Query: 645 YTMKSDVYSFGVVMLELLTGRKPFDSSKPRSEQSLVRWASPQLHDIDALDRMVDPALKGL 466 Y K+D++SFG+ +EL TG P+ P L P + D+ + Sbjct: 259 YDFKADMWSFGITAIELATGAAPYHKYPPMKVLMLTLQNDPPTLETGVEDKEM------- 311 Query: 465 YPAKSLSRFADVLALCVQAEPEFRPPMSEVVQALVRLVQRANMTKKMLDGDASRRGD 295 K F +L+LC+Q +P RP +E+++ + Q+A + +++ +R D Sbjct: 312 -MKKYGKSFRKLLSLCLQKDPSKRPTAAELLKC--KFFQKAKNREYLIEKLLTRTPD 365
>IRAK4_MOUSE (Q8R4K2) Interleukin-1 receptor-associated kinase 4 (EC 2.7.11.1)| (IRAK-4) Length = 459 Score = 43.1 bits (100), Expect = 7e-04 Identities = 29/96 (30%), Positives = 49/96 (51%), Gaps = 1/96 (1%) Frame = -3 Query: 648 QYTMKSDVYSFGVVMLELLTGRKPFDSSKPRSEQSLVRWASPQLHDID-ALDRMVDPALK 472 + T KSD+YSFGVV+LEL+TG D ++ E L+ ++ D + ++ D + Sbjct: 363 EITPKSDIYSFGVVLLELITGLAAVDENR---EPQLLLDIKEEIEDEEKTIEDYTDEKMS 419 Query: 471 GLYPAKSLSRFADVLALCVQAEPEFRPPMSEVVQAL 364 PA S+ + C+ + RP +++V Q L Sbjct: 420 DADPA-SVEAMYSAASQCLHEKKNRRPDIAKVQQLL 454
>KYK1_DICDI (P18160) Non-receptor tyrosine kinase spore lysis A (EC 2.7.10.2)| (Tyrosine-protein kinase 1) Length = 1584 Score = 42.7 bits (99), Expect = 0.001 Identities = 24/88 (27%), Positives = 40/88 (45%) Frame = -3 Query: 636 KSDVYSFGVVMLELLTGRKPFDSSKPRSEQSLVRWASPQLHDIDALDRMVDPALKGLYPA 457 KSDVYS+G+V+ ELLT +P KP L + S + P Sbjct: 1485 KSDVYSYGMVLFELLTSDEPQQDMKPMKMAHLAAYES----------------YRPPIPL 1528 Query: 456 KSLSRFADVLALCVQAEPEFRPPMSEVV 373 + S++ ++L C + P+ RP +++ Sbjct: 1529 TTSSKWKEILTQCWDSNPDSRPTFKQII 1556
>STK24_MOUSE (Q99KH8) Serine/threonine-protein kinase 24 (EC 2.7.11.1)| Length = 431 Score = 42.4 bits (98), Expect = 0.001 Identities = 29/124 (23%), Positives = 54/124 (43%), Gaps = 2/124 (1%) Frame = -3 Query: 645 YTMKSDVYSFGVVMLELLTGRKPFDSSKPRSEQSLVRWASPQLHDIDALDRMVDPALKGL 466 Y K+D++S G+ +EL G P P L+ +P P L+G Sbjct: 196 YDSKADIWSLGITAIELAKGEPPHSELHPMKVLFLIPKNNP-------------PTLEGN 242 Query: 465 YPAKSLSRFADVLALCVQAEPEFRPPMSEVV--QALVRLVQRANMTKKMLDGDASRRGDD 292 Y +K L F + C+ EP FRP E++ + ++R ++ + +++D + + Sbjct: 243 Y-SKPLKEFVEA---CLNKEPSFRPTAKELLKHKFIIRNAKKTSYLTELIDRYKRWKAEQ 298 Query: 291 QDQD 280 +D Sbjct: 299 SHED 302
>IRAK3_MOUSE (Q8K4B2) Interleukin-1 receptor-associated kinase 3 (EC 2.7.11.1)| (IRAK-3) (IL-1 receptor-associated kinase M) (IRAK-M) Length = 609 Score = 42.0 bits (97), Expect = 0.002 Identities = 29/97 (29%), Positives = 48/97 (49%), Gaps = 4/97 (4%) Frame = -3 Query: 642 TMKSDVYSFGVVMLELLTGRKPF--DSSKPRSEQSLVRWASPQLHD--IDALDRMVDPAL 475 ++K+DVYSFG+V++E+LTG K D + L+ + D + LDR + P Sbjct: 365 SVKTDVYSFGIVIMEVLTGCKVVLDDPKHVQLRDLLMELMEKRGLDSCLSFLDRKIPPC- 423 Query: 474 KGLYPAKSLSRFADVLALCVQAEPEFRPPMSEVVQAL 364 P ++ + CV + + RP M EV+ +L Sbjct: 424 ----PRNFSAKLFSLAGRCVATKAKLRPTMDEVLSSL 456
>KYK2_DICDI (P18161) Tyrosine-protein kinase 2 (EC 2.7.10.2) (Fragment)| Length = 410 Score = 42.0 bits (97), Expect = 0.002 Identities = 30/99 (30%), Positives = 42/99 (42%), Gaps = 5/99 (5%) Frame = -3 Query: 645 YTMKSDVYSFGVVMLELLTGRKPFDSSKPRSEQSLVRWASPQLHDIDALDRMVDPALKGL 466 Y+ K DVY F +V+ E+LTG PF D+D R A GL Sbjct: 287 YSEKVDVYCFSLVVWEILTGEIPFS-------------------DLDGSQRSAQVAYAGL 327 Query: 465 YPAKSLSRFAD-----VLALCVQAEPEFRPPMSEVVQAL 364 P + + D +L C +A+P RPP + +V L Sbjct: 328 RP--PIPEYCDPELKLLLTQCWEADPNDRPPFTYIVNKL 364
>M3K7_MOUSE (Q62073) Mitogen-activated protein kinase kinase kinase 7 (EC| 2.7.11.25) (Transforming growth factor-beta-activated kinase 1) (TGF-beta-activated kinase 1) Length = 579 Score = 41.6 bits (96), Expect = 0.002 Identities = 30/100 (30%), Positives = 52/100 (52%), Gaps = 1/100 (1%) Frame = -3 Query: 645 YTMKSDVYSFGVVMLELLTGRKPFDSSKPRSEQSLVRWASPQLHDIDALDRMVDPALKGL 466 Y+ K DV+S+G+++ E++T RKPFD + + + WA +H + P +K L Sbjct: 206 YSEKCDVFSWGIILWEVITRRKPFDEIGGPAFR--IMWA---VH-----NGTRPPLIKNL 255 Query: 465 -YPAKSLSRFADVLALCVQAEPEFRPPMSEVVQALVRLVQ 349 P +SL + C +P RP M E+V+ + L++ Sbjct: 256 PKPIESL------MTRCWSKDPSQRPSMEEIVKIMTHLMR 289
>M3LK7_DROME (P83104) Putative mitogen-activated protein kinase kinase kinase| 7-like (EC 2.7.11.25) Length = 393 Score = 41.6 bits (96), Expect = 0.002 Identities = 26/96 (27%), Positives = 49/96 (51%), Gaps = 1/96 (1%) Frame = -3 Query: 648 QYTMKSDVYSFGVVMLELLTGRKPFDS-SKPRSEQSLVRWASPQLHDIDALDRMVDPALK 472 +YT K DVYSFG+++ EL+T + P+ P S+ ++++ I + +++ A++ Sbjct: 182 KYTAKCDVYSFGIMLWELMTRQLPYSHLENPNSQYAIMK-------AISSGEKLPMEAVR 234 Query: 471 GLYPAKSLSRFADVLALCVQAEPEFRPPMSEVVQAL 364 P ++ C+ PE RP M E+ + L Sbjct: 235 SDCP----EGIKQLMECCMDINPEKRPSMKEIEKFL 266
>ITK_MOUSE (Q03526) Tyrosine-protein kinase ITK/TSK (EC 2.7.10.2)| (T-cell-specific kinase) (IL-2-inducible T-cell kinase) (Kinase EMT) (Kinase TLK) Length = 625 Score = 41.6 bits (96), Expect = 0.002 Identities = 29/101 (28%), Positives = 52/101 (51%), Gaps = 1/101 (0%) Frame = -3 Query: 648 QYTMKSDVYSFGVVMLELLT-GRKPFDSSKPRSEQSLVRWASPQLHDIDALDRMVDPALK 472 +Y+ KSDV+SFGV+M E+ + G+ P+++ RS +V DI R+ P L Sbjct: 539 RYSSKSDVWSFGVLMWEVFSEGKIPYEN---RSNSEVV-------EDISTGFRLYKPRLA 588 Query: 471 GLYPAKSLSRFADVLALCVQAEPEFRPPMSEVVQALVRLVQ 349 + + ++ C + +PE RPP S+++ L + + Sbjct: 589 SCHVYQIMNH-------CWKEKPEDRPPFSQLLSQLAEIAE 622
>BRI1_LYCPE (Q8L899) Systemin receptor SR160 precursor (EC 2.7.11.1)| (Brassinosteroid LRR receptor kinase) Length = 1207 Score = 41.6 bits (96), Expect = 0.002 Identities = 20/35 (57%), Positives = 27/35 (77%) Frame = -3 Query: 636 KSDVYSFGVVMLELLTGRKPFDSSKPRSEQSLVRW 532 K DVYS+GVV+LELLTG++P DS+ + +LV W Sbjct: 1071 KGDVYSYGVVLLELLTGKQPTDSA-DFGDNNLVGW 1104
>BRI1_LYCES (Q8GUQ5) Brassinosteroid LRR receptor kinase precursor (EC 2.7.11.1)| (tBRI1) (Altered brassinolide sensitivity 1) (Systemin receptor SR160) Length = 1207 Score = 41.6 bits (96), Expect = 0.002 Identities = 20/35 (57%), Positives = 27/35 (77%) Frame = -3 Query: 636 KSDVYSFGVVMLELLTGRKPFDSSKPRSEQSLVRW 532 K DVYS+GVV+LELLTG++P DS+ + +LV W Sbjct: 1071 KGDVYSYGVVLLELLTGKQPTDSA-DFGDNNLVGW 1104
>M3K7_HUMAN (O43318) Mitogen-activated protein kinase kinase kinase 7 (EC| 2.7.11.25) (Transforming growth factor-beta-activated kinase 1) (TGF-beta-activated kinase 1) Length = 606 Score = 41.6 bits (96), Expect = 0.002 Identities = 30/100 (30%), Positives = 52/100 (52%), Gaps = 1/100 (1%) Frame = -3 Query: 645 YTMKSDVYSFGVVMLELLTGRKPFDSSKPRSEQSLVRWASPQLHDIDALDRMVDPALKGL 466 Y+ K DV+S+G+++ E++T RKPFD + + + WA +H + P +K L Sbjct: 206 YSEKCDVFSWGIILWEVITRRKPFDEIGGPAFR--IMWA---VH-----NGTRPPLIKNL 255 Query: 465 -YPAKSLSRFADVLALCVQAEPEFRPPMSEVVQALVRLVQ 349 P +SL + C +P RP M E+V+ + L++ Sbjct: 256 PKPIESL------MTRCWSKDPSQRPSMEEIVKIMTHLMR 289
>MP2K6_HUMAN (P52564) Dual specificity mitogen-activated protein kinase kinase 6| (EC 2.7.12.2) (MAP kinase kinase 6) (MAPKK 6) (MAPK/ERK kinase 6) (SAPKK3) Length = 334 Score = 41.6 bits (96), Expect = 0.002 Identities = 26/92 (28%), Positives = 44/92 (47%) Frame = -3 Query: 645 YTMKSDVYSFGVVMLELLTGRKPFDSSKPRSEQSLVRWASPQLHDIDALDRMVDPALKGL 466 Y++KSD++S G+ M+EL R P+DS W +P L ++V+ L Sbjct: 234 YSVKSDIWSLGITMIELAILRFPYDS-----------WGTP----FQQLKQVVEEPSPQL 278 Query: 465 YPAKSLSRFADVLALCVQAEPEFRPPMSEVVQ 370 K + F D + C++ + RP E++Q Sbjct: 279 PADKFSAEFVDFTSQCLKKNSKERPTYPELMQ 310
>STK24_HUMAN (Q9Y6E0) Serine/threonine-protein kinase 24 (EC 2.7.11.1)| (STE20-like kinase MST3) (MST-3) (Mammalian STE20-like protein kinase 3) Length = 443 Score = 41.2 bits (95), Expect = 0.003 Identities = 28/111 (25%), Positives = 50/111 (45%), Gaps = 2/111 (1%) Frame = -3 Query: 645 YTMKSDVYSFGVVMLELLTGRKPFDSSKPRSEQSLVRWASPQLHDIDALDRMVDPALKGL 466 Y K+D++S G+ +EL G P P L+ +P P L+G Sbjct: 208 YDSKADIWSLGITAIELARGEPPHSELHPMKVLFLIPKNNP-------------PTLEGN 254 Query: 465 YPAKSLSRFADVLALCVQAEPEFRPPMSEVV--QALVRLVQRANMTKKMLD 319 Y +K L F + C+ EP FRP E++ + ++R ++ + +++D Sbjct: 255 Y-SKPLKEFVEA---CLNKEPSFRPTAKELLKHKFILRNAKKTSYLTELID 301
>TEC_MOUSE (P24604) Tyrosine-protein kinase Tec (EC 2.7.10.2)| Length = 630 Score = 40.8 bits (94), Expect = 0.004 Identities = 32/105 (30%), Positives = 52/105 (49%), Gaps = 5/105 (4%) Frame = -3 Query: 648 QYTMKSDVYSFGVVMLELLT-GRKPFDSSKPRSEQSLV----RWASPQLHDIDALDRMVD 484 +++ KSDV+SFGV+M E+ T GR PF+ + ++V R P+L Sbjct: 540 RFSSKSDVWSFGVLMWEIFTEGRMPFEKNTNYEVVTMVTRGHRLHRPKL----------- 588 Query: 483 PALKGLYPAKSLSRFADVLALCVQAEPEFRPPMSEVVQALVRLVQ 349 A K LY +V+ C Q PE RP + ++++ + LV+ Sbjct: 589 -ATKYLY---------EVMLRCWQERPEGRPSLEDLLRTIDELVE 623
>MP2K6_MOUSE (P70236) Dual specificity mitogen-activated protein kinase kinase 6| (EC 2.7.12.2) (MAP kinase kinase 6) (MAPKK 6) (MAPK/ERK kinase 6) (SAPKK3) Length = 334 Score = 40.8 bits (94), Expect = 0.004 Identities = 26/92 (28%), Positives = 44/92 (47%) Frame = -3 Query: 645 YTMKSDVYSFGVVMLELLTGRKPFDSSKPRSEQSLVRWASPQLHDIDALDRMVDPALKGL 466 Y++KSD++S G+ M+EL R P+DS W +P L ++V+ L Sbjct: 234 YSVKSDIWSLGITMIELAILRFPYDS-----------WGTP----FQQLKQVVEEPSPQL 278 Query: 465 YPAKSLSRFADVLALCVQAEPEFRPPMSEVVQ 370 K + F D + C++ + RP E++Q Sbjct: 279 PADKFSADFVDFTSQCLKKNSKERPTYPELMQ 310
>BRAF1_COTJA (P34908) B-Raf proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (RMIL serine/threonine-protein kinase) (c-RMIL) Length = 807 Score = 40.4 bits (93), Expect = 0.005 Identities = 27/123 (21%), Positives = 55/123 (44%) Frame = -3 Query: 645 YTMKSDVYSFGVVMLELLTGRKPFDSSKPRSEQSLVRWASPQLHDIDALDRMVDPALKGL 466 Y+ +SDVY+FG+V+ EL+TG+ P+ + R + + D+ + A+K L Sbjct: 673 YSFQSDVYAFGIVLYELMTGQLPYSNINNRDQIIFMVGRGYLSPDLSKVRSNCPKAMKRL 732 Query: 465 YPAKSLSRFADVLALCVQAEPEFRPPMSEVVQALVRLVQRANMTKKMLDGDASRRGDDQD 286 +A C++ + + RP +++ ++ L + + + R Q Sbjct: 733 ------------MAECLKKKRDERPLFPQILASIELLARSLPKIHRSASEPSLNRAGFQT 780 Query: 285 QDF 277 +DF Sbjct: 781 EDF 783
>RMIL_AVEVR (P27966) Serine/threonine-protein kinase transforming protein Rmil| (EC 2.7.11.1) Length = 450 Score = 40.4 bits (93), Expect = 0.005 Identities = 27/123 (21%), Positives = 55/123 (44%) Frame = -3 Query: 645 YTMKSDVYSFGVVMLELLTGRKPFDSSKPRSEQSLVRWASPQLHDIDALDRMVDPALKGL 466 Y+ +SDVY+FG+V+ EL+TG+ P+ + R + + D+ + A+K L Sbjct: 259 YSFQSDVYAFGIVLYELMTGQLPYSNINNRDQIIFMVGRGYLSPDLSKVRSNCPKAMKRL 318 Query: 465 YPAKSLSRFADVLALCVQAEPEFRPPMSEVVQALVRLVQRANMTKKMLDGDASRRGDDQD 286 +A C++ + + RP +++ ++ L + + + R Q Sbjct: 319 ------------MAECLKKKRDERPLFPQILASIELLARSLPKIHRSASEPSLNRAGFQT 366 Query: 285 QDF 277 +DF Sbjct: 367 EDF 369
>RMIL_AVII1 (P10533) Serine/threonine-protein kinase transforming protein Rmil| (EC 2.7.11.1) Length = 367 Score = 40.4 bits (93), Expect = 0.005 Identities = 27/123 (21%), Positives = 55/123 (44%) Frame = -3 Query: 645 YTMKSDVYSFGVVMLELLTGRKPFDSSKPRSEQSLVRWASPQLHDIDALDRMVDPALKGL 466 Y+ +SDVY+FG+V+ EL+TG+ P+ + R + + D+ + A+K L Sbjct: 243 YSFQSDVYAFGIVLYELMTGQLPYSNINNRDQIIFMVGRGYLSPDLSKVRSNCPKAMKRL 302 Query: 465 YPAKSLSRFADVLALCVQAEPEFRPPMSEVVQALVRLVQRANMTKKMLDGDASRRGDDQD 286 +A C++ + + RP +++ ++ L + + + R Q Sbjct: 303 ------------MAECLKKKRDERPLFPQILASIELLARSLPKIHRSASEPSLNRAGFQT 350 Query: 285 QDF 277 +DF Sbjct: 351 EDF 353
>IRAK4_HUMAN (Q9NWZ3) Interleukin-1 receptor-associated kinase 4 (EC 2.7.11.1)| (IRAK-4) (NY-REN-64 antigen) Length = 460 Score = 40.4 bits (93), Expect = 0.005 Identities = 29/100 (29%), Positives = 49/100 (49%), Gaps = 5/100 (5%) Frame = -3 Query: 648 QYTMKSDVYSFGVVMLELLTGRKPFDSSKPRSEQSLVRWASPQLHD-----IDALDRMVD 484 + T KSD+YSFGVV+LE++TG D + E L+ ++ D D +D+ ++ Sbjct: 363 EITPKSDIYSFGVVLLEIITGLPAVDEHR---EPQLLLDIKEEIEDEEKTIEDYIDKKMN 419 Query: 483 PALKGLYPAKSLSRFADVLALCVQAEPEFRPPMSEVVQAL 364 A + S+ V + C+ + RP + +V Q L Sbjct: 420 DA-----DSTSVEAMYSVASQCLHEKKNKRPDIKKVQQLL 454
>BRAF1_HUMAN (P15056) B-Raf proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (p94) (v-Raf murine sarcoma viral oncogene homolog B1) Length = 766 Score = 40.4 bits (93), Expect = 0.005 Identities = 27/123 (21%), Positives = 55/123 (44%) Frame = -3 Query: 645 YTMKSDVYSFGVVMLELLTGRKPFDSSKPRSEQSLVRWASPQLHDIDALDRMVDPALKGL 466 Y+ +SDVY+FG+V+ EL+TG+ P+ + R + + D+ + A+K L Sbjct: 633 YSFQSDVYAFGIVLYELMTGQLPYSNINNRDQIIFMVGRGYLSPDLSKVRSNCPKAMKRL 692 Query: 465 YPAKSLSRFADVLALCVQAEPEFRPPMSEVVQALVRLVQRANMTKKMLDGDASRRGDDQD 286 +A C++ + + RP +++ ++ L + + + R Q Sbjct: 693 ------------MAECLKKKRDERPLFPQILASIELLARSLPKIHRSASEPSLNRAGFQT 740 Query: 285 QDF 277 +DF Sbjct: 741 EDF 743
>BRAF1_MOUSE (P28028) B-Raf proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (Fragment) Length = 328 Score = 40.4 bits (93), Expect = 0.005 Identities = 27/123 (21%), Positives = 55/123 (44%) Frame = -3 Query: 645 YTMKSDVYSFGVVMLELLTGRKPFDSSKPRSEQSLVRWASPQLHDIDALDRMVDPALKGL 466 Y+ +SDVY+FG+V+ EL+TG+ P+ + R + + D+ + A+K L Sbjct: 195 YSFQSDVYAFGIVLYELMTGQLPYSNINNRDQIIFMVGRGYLSPDLSKVRSNCPKAMKRL 254 Query: 465 YPAKSLSRFADVLALCVQAEPEFRPPMSEVVQALVRLVQRANMTKKMLDGDASRRGDDQD 286 +A C++ + + RP +++ ++ L + + + R Q Sbjct: 255 ------------MAECLKKKRDERPLFPQILASIELLARSLPKIHRSASEPSLNRAGFQT 302 Query: 285 QDF 277 +DF Sbjct: 303 EDF 305
>BRAF1_CHICK (Q04982) B-Raf proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (Rmil serine/threonine-protein kinase) (c-Rmil) Length = 806 Score = 40.4 bits (93), Expect = 0.005 Identities = 27/123 (21%), Positives = 55/123 (44%) Frame = -3 Query: 645 YTMKSDVYSFGVVMLELLTGRKPFDSSKPRSEQSLVRWASPQLHDIDALDRMVDPALKGL 466 Y+ +SDVY+FG+V+ EL+TG+ P+ + R + + D+ + A+K L Sbjct: 673 YSFQSDVYAFGIVLYELMTGQLPYSNINNRDQIIFMVGRGYLSPDLSKVRSNCPKAMKRL 732 Query: 465 YPAKSLSRFADVLALCVQAEPEFRPPMSEVVQALVRLVQRANMTKKMLDGDASRRGDDQD 286 +A C++ + + RP +++ ++ L + + + R Q Sbjct: 733 ------------MAECLKKKRDERPLFPQILASIELLARSLPKIHRSASEPSLNRAGFQT 780 Query: 285 QDF 277 +DF Sbjct: 781 EDF 783
>KPRO_MAIZE (P17801) Putative receptor protein kinase ZmPK1 precursor (EC| 2.7.11.1) Length = 817 Score = 40.0 bits (92), Expect = 0.006 Identities = 34/104 (32%), Positives = 50/104 (48%), Gaps = 10/104 (9%) Frame = -3 Query: 642 TMKSDVYSFGVVMLELLTGRKPFDSSKPRSE-----QSLVRWASPQLHDIDA--LDRMVD 484 T K DVYS+GVV+LELLTG + + E + LVR S +L + +D +D Sbjct: 713 TAKVDVYSYGVVLLELLTGTRVSELVGGTDEVHSMLRKLVRMLSAKLEGEEQSWIDGYLD 772 Query: 483 PALK---GLYPAKSLSRFADVLALCVQAEPEFRPPMSEVVQALV 361 L A++L + A C++ + RP M VQ L+ Sbjct: 773 SKLNRPVNYVQARTLIKLA---VSCLEEDRSKRPTMEHAVQTLL 813
>PHY1_CERPU (P25848) Light-sensor Protein kinase [Includes: Phytochrome; Protein| kinase (EC 2.7.11.1)] Length = 1307 Score = 40.0 bits (92), Expect = 0.006 Identities = 28/95 (29%), Positives = 43/95 (45%) Frame = -3 Query: 648 QYTMKSDVYSFGVVMLELLTGRKPFDSSKPRSEQSLVRWASPQLHDIDALDRMVDPALKG 469 +Y +KSDVYSFG+V E+LTG PF P+ + + + RMV ++ Sbjct: 1204 KYPLKSDVYSFGMVCYEVLTGDVPF----------------PEEKNPNNVKRMVLEGVRP 1247 Query: 468 LYPAKSLSRFADVLALCVQAEPEFRPPMSEVVQAL 364 PA ++ C +P RP + + Q L Sbjct: 1248 DLPAHCPIELKALITDCWNQDPLKRPSFAVICQKL 1282
>HT1_ARATH (Q2MHE4) Serine/threonine-protein kinase HT1 (EC 2.7.11.1) (High| leaf temperature protein 1) Length = 390 Score = 40.0 bits (92), Expect = 0.006 Identities = 27/94 (28%), Positives = 36/94 (38%) Frame = -3 Query: 645 YTMKSDVYSFGVVMLELLTGRKPFDSSKPRSEQSLVRWASPQLHDIDALDRMVDPALKGL 466 YT K DVYSFG+V+ EL T PF P + A + + + Sbjct: 263 YTRKVDVYSFGIVLWELTTALLPFQGMTP----------------VQAAFAVAEKNERPP 306 Query: 465 YPAKSLSRFADVLALCVQAEPEFRPPMSEVVQAL 364 PA A ++ C P RP S +V L Sbjct: 307 LPASCQPALAHLIKRCWSENPSKRPDFSNIVAVL 340
>IRAK3_HUMAN (Q9Y616) Interleukin-1 receptor-associated kinase 3 (EC 2.7.11.1)| (IRAK-3) (IL-1 receptor-associated kinase M) (IRAK-M) Length = 596 Score = 39.7 bits (91), Expect = 0.008 Identities = 30/98 (30%), Positives = 48/98 (48%), Gaps = 5/98 (5%) Frame = -3 Query: 642 TMKSDVYSFGVVMLELLTG-RKPFDSSKPRSEQSLVRWASPQLHDIDA----LDRMVDPA 478 ++K+DVYSFG+V++E+LTG R D K + L+R + +D+ LD+ V P Sbjct: 352 SIKTDVYSFGIVIMEVLTGCRVVLDDPKHIQLRDLLR-ELMEKRGLDSCLSFLDKKVPPC 410 Query: 477 LKGLYPAKSLSRFADVLALCVQAEPEFRPPMSEVVQAL 364 P ++ + C + RP M EV+ L Sbjct: 411 -----PRNFSAKLFCLAGRCAATRAKLRPSMDEVLNTL 443
>TEC_HUMAN (P42680) Tyrosine-protein kinase Tec (EC 2.7.10.2)| Length = 631 Score = 39.7 bits (91), Expect = 0.008 Identities = 29/101 (28%), Positives = 48/101 (47%), Gaps = 1/101 (0%) Frame = -3 Query: 648 QYTMKSDVYSFGVVMLELLT-GRKPFDSSKPRSEQSLVRWASPQLHDIDALDRMVDPALK 472 +++ KSDV+SFGV+M E+ T GR PF+ ++V R+ P L Sbjct: 541 RFSSKSDVWSFGVLMWEVFTEGRMPFEKYTNYEVVTMVTRG----------HRLYQPKLA 590 Query: 471 GLYPAKSLSRFADVLALCVQAEPEFRPPMSEVVQALVRLVQ 349 Y +V+ C Q +PE RP ++++ + LV+ Sbjct: 591 SNY-------VYEVMLRCWQEKPEGRPSFEDLLRTIDELVE 624
>NEK9_XENLA (Q7ZZC8) Serine/threonine-protein kinase Nek9 (EC 2.7.11.1)| (NimA-related protein kinase 9) (XNek9) (Nercc1 kinase) Length = 944 Score = 39.7 bits (91), Expect = 0.008 Identities = 27/111 (24%), Positives = 51/111 (45%), Gaps = 3/111 (2%) Frame = -3 Query: 648 QYTMKSDVYSFGVVMLELLTGRKPFDSSKPRSEQSLV---RWASPQLHDIDALDRMVDPA 478 +Y+ KSD+++ G V+ ELLT + FD++ P + + WA Sbjct: 209 KYSFKSDIWAVGCVLYELLTLTRTFDATNPLNLCVKIVQGNWA----------------- 251 Query: 477 LKGLYPAKSLSRFADVLALCVQAEPEFRPPMSEVVQALVRLVQRANMTKKM 325 GL +V+ C++ +PE RP E+++ + +R +M +K+ Sbjct: 252 -VGLDNTVYTQELIEVVHACLEQDPEKRPTADEILERPILSWRRRDMEEKV 301
>PKNL_MYCTU (O53510) Probable serine/threonine-protein kinase pknL (EC| 2.7.11.1) Length = 399 Score = 39.3 bits (90), Expect = 0.010 Identities = 32/97 (32%), Positives = 50/97 (51%), Gaps = 14/97 (14%) Frame = -3 Query: 636 KSDVYSFGVVMLELLTGRKPF-------------DSSKPRSEQSLVRWASPQLHDIDALD 496 +SDVYS GV++ ELLTG PF D+ PR+ +++ PQ ++ A Sbjct: 198 RSDVYSVGVLVYELLTGHTPFTGDSALSIAYQRLDADVPRA-SAVIDGVPPQFDELVACA 256 Query: 495 RMVDPALKGLYPAKSLSRFADVLALCVQ-AEPEFRPP 388 +PA + A +++ AD+ A+ + A PEFR P Sbjct: 257 TARNPADR---YADAIAMGADLEAIAEELALPEFRVP 290
>PKNL_MYCBO (Q7TYY6) Probable serine/threonine-protein kinase pknL (EC| 2.7.11.1) Length = 399 Score = 39.3 bits (90), Expect = 0.010 Identities = 32/97 (32%), Positives = 50/97 (51%), Gaps = 14/97 (14%) Frame = -3 Query: 636 KSDVYSFGVVMLELLTGRKPF-------------DSSKPRSEQSLVRWASPQLHDIDALD 496 +SDVYS GV++ ELLTG PF D+ PR+ +++ PQ ++ A Sbjct: 198 RSDVYSVGVLVYELLTGHTPFTGDSALSIAYQRLDADVPRA-SAVIDGVPPQFDELVACA 256 Query: 495 RMVDPALKGLYPAKSLSRFADVLALCVQ-AEPEFRPP 388 +PA + A +++ AD+ A+ + A PEFR P Sbjct: 257 TARNPADR---YADAIAMGADLEAIAEELALPEFRVP 290
>PKN2_BACSU (O34507) Probable serine/threonine-protein kinase yloP (EC| 2.7.11.1) Length = 648 Score = 39.3 bits (90), Expect = 0.010 Identities = 16/24 (66%), Positives = 20/24 (83%) Frame = -3 Query: 642 TMKSDVYSFGVVMLELLTGRKPFD 571 T KSD+Y+ G+V+ ELLTGR PFD Sbjct: 188 TKKSDIYALGIVLFELLTGRIPFD 211
>PGFRB_RAT (Q05030) Beta platelet-derived growth factor receptor precursor (EC| 2.7.10.1) (PDGF-R-beta) Length = 1097 Score = 39.3 bits (90), Expect = 0.010 Identities = 27/99 (27%), Positives = 45/99 (45%), Gaps = 1/99 (1%) Frame = -3 Query: 645 YTMKSDVYSFGVVMLELLT-GRKPFDSSKPRSEQSLVRWASPQLHDIDALDRMVDPALKG 469 YT SDV+SFG+++ E+ T G P+ P+L D + + Sbjct: 879 YTTLSDVWSFGILLWEIFTLGGTPY----------------PELPMNDQFYNAIKRGYRM 922 Query: 468 LYPAKSLSRFADVLALCVQAEPEFRPPMSEVVQALVRLV 352 PA + +++ C + + E RPP S++V L RL+ Sbjct: 923 AQPAHASDEIYEIMQKCWEEKFETRPPFSQLVLLLERLL 961
>PGFRB_MOUSE (P05622) Beta platelet-derived growth factor receptor precursor (EC| 2.7.10.1) (PDGF-R-beta) Length = 1098 Score = 39.3 bits (90), Expect = 0.010 Identities = 27/99 (27%), Positives = 45/99 (45%), Gaps = 1/99 (1%) Frame = -3 Query: 645 YTMKSDVYSFGVVMLELLT-GRKPFDSSKPRSEQSLVRWASPQLHDIDALDRMVDPALKG 469 YT SDV+SFG+++ E+ T G P+ P+L D + + Sbjct: 879 YTTLSDVWSFGILLWEIFTLGGTPY----------------PELPMNDQFYNAIKRGYRM 922 Query: 468 LYPAKSLSRFADVLALCVQAEPEFRPPMSEVVQALVRLV 352 PA + +++ C + + E RPP S++V L RL+ Sbjct: 923 AQPAHASDEIYEIMQKCWEEKFETRPPFSQLVLLLERLL 961
>AL2S2_MOUSE (Q8K4T3) Serine/threonine-protein kinase ALS2CR2 (EC 2.7.11.1)| (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 2 protein homolog) (ILP-interacting protein homolog) (Polyploidy-associated protein kinase) Length = 418 Score = 39.3 bits (90), Expect = 0.010 Identities = 34/126 (26%), Positives = 52/126 (41%), Gaps = 35/126 (27%) Frame = -3 Query: 645 YTMKSDVYSFGVVMLELLTGRKPF----------------------------DSSKPRSE 550 Y +KSD+YS G+ EL +G+ PF S+ R+ Sbjct: 245 YNVKSDIYSVGITACELASGQVPFQDMHRTQMLLQKLKGPPYSPLDVSIFPQSDSRMRNS 304 Query: 549 QSLVR-------WASPQLHDIDALDRMVDPALKGLYPAKSLSRFADVLALCVQAEPEFRP 391 QS V S H +++ DR+ P+ K PA F ++ LC+Q +PE RP Sbjct: 305 QSGVDSGIGESVLVSTGTHTVNS-DRLHTPSTKTFSPA-----FFSLVQLCLQQDPEKRP 358 Query: 390 PMSEVV 373 S ++ Sbjct: 359 SASSLL 364
>PKN2_MYXXA (P54736) Serine/threonine-protein kinase pkn2 (EC 2.7.11.1)| Length = 830 Score = 38.9 bits (89), Expect = 0.013 Identities = 27/75 (36%), Positives = 40/75 (53%) Frame = -3 Query: 636 KSDVYSFGVVMLELLTGRKPFDSSKPRSEQSLVRWASPQLHDIDALDRMVDPALKGLYPA 457 +SD+YSFGV+ +L+GR PFD PR+ S A+P LDR A Sbjct: 197 RSDLYSFGVLTYRVLSGRLPFDGPLPRNFLSQHASAAPL-----PLDR----------AA 241 Query: 456 KSLSRFADVLALCVQ 412 +LSR+ +L+L ++ Sbjct: 242 PTLSRYVGLLSLVMR 256
>PBS2_YEAST (P08018) MAP kinase kinase PBS2 (EC 2.7.12.2) (Polymyxin B| resistance protein 2) (Suppressor of fluoride sensitivity 4) Length = 668 Score = 38.9 bits (89), Expect = 0.013 Identities = 27/94 (28%), Positives = 44/94 (46%), Gaps = 2/94 (2%) Frame = -3 Query: 645 YTMKSDVYSFGVVMLELLTGRKPFDSSKPRSEQSLVRWASPQLHD--IDALDRMVDPALK 472 YT++SD++S G+ +LE+ GR P+ P+ +D L +VD Sbjct: 541 YTVQSDIWSLGLSILEMALGRYPY---------------PPETYDNIFSQLSAIVDGPPP 585 Query: 471 GLYPAKSLSRFADVLALCVQAEPEFRPPMSEVVQ 370 L K S D ++LC+Q PE RP + + + Sbjct: 586 RLPSDKFSSDAQDFVSLCLQKIPERRPTYAALTE 619
>PKSC_STRCO (Q9S2C0) Serine/threonine protein kinase pksC (EC 2.7.11.1)| Length = 556 Score = 38.5 bits (88), Expect = 0.017 Identities = 20/59 (33%), Positives = 36/59 (61%), Gaps = 2/59 (3%) Frame = -3 Query: 636 KSDVYSFGVVMLELLTGRKPFDSSKPRSEQSLVRWASPQLHDI--DALDRMVDPALKGL 466 +SD+YS G+++ +L+TGR PFD+ P + + +A Q + A++R + PA+ L Sbjct: 209 RSDLYSVGIMLFQLVTGRLPFDADSPLA----IAYAHVQEQPVAPSAVNRALPPAVDAL 263
>PGFRB_CANFA (Q6QNF3) Beta platelet-derived growth factor receptor precursor (EC| 2.7.10.1) (PDGF-R-beta) Length = 1103 Score = 38.5 bits (88), Expect = 0.017 Identities = 26/99 (26%), Positives = 45/99 (45%), Gaps = 1/99 (1%) Frame = -3 Query: 645 YTMKSDVYSFGVVMLELLT-GRKPFDSSKPRSEQSLVRWASPQLHDIDALDRMVDPALKG 469 YT SDV+SFG+++ E+ T G P+ P+L + + + Sbjct: 880 YTTLSDVWSFGILLWEIFTLGGTPY----------------PELPMNEQFYNAIKRGYRM 923 Query: 468 LYPAKSLSRFADVLALCVQAEPEFRPPMSEVVQALVRLV 352 PA + +++ C + + E RPP S++V L RL+ Sbjct: 924 AQPAHASDEIYEIMQKCWEEKFEIRPPFSQLVLLLERLL 962
>PGFRB_HUMAN (P09619) Beta platelet-derived growth factor receptor precursor (EC| 2.7.10.1) (PDGF-R-beta) (CD140b antigen) Length = 1106 Score = 38.5 bits (88), Expect = 0.017 Identities = 26/99 (26%), Positives = 45/99 (45%), Gaps = 1/99 (1%) Frame = -3 Query: 645 YTMKSDVYSFGVVMLELLT-GRKPFDSSKPRSEQSLVRWASPQLHDIDALDRMVDPALKG 469 YT SDV+SFG+++ E+ T G P+ P+L + + + Sbjct: 880 YTTLSDVWSFGILLWEIFTLGGTPY----------------PELPMNEQFYNAIKRGYRM 923 Query: 468 LYPAKSLSRFADVLALCVQAEPEFRPPMSEVVQALVRLV 352 PA + +++ C + + E RPP S++V L RL+ Sbjct: 924 AQPAHASDEIYEIMQKCWEEKFEIRPPFSQLVLLLERLL 962
>MIL_AVIMH (P00531) Serine/threonine-protein kinase transforming protein mil| (EC 2.7.11.1) Length = 380 Score = 38.5 bits (88), Expect = 0.017 Identities = 28/98 (28%), Positives = 48/98 (48%), Gaps = 9/98 (9%) Frame = -3 Query: 645 YTMKSDVYSFGVVMLELLTGRKPFDSSKPRSEQSLV---RWASPQLHDI-----DALDRM 490 ++ +SDVYS+G+V+ EL+TG P+ R + + +ASP L + A+ R+ Sbjct: 258 FSFQSDVYSYGIVLYELMTGELPYSHINNRDQIIFMVGRGYASPDLSKLYKNCPKAMKRL 317 Query: 489 VDPALKGLYPAKSL-SRFADVLALCVQAEPEFRPPMSE 379 V LK + + L + +AL + P+ SE Sbjct: 318 VADCLKKVREERPLFPQILSSIALLQHSLPKINRSASE 355
>M3K10_HUMAN (Q02779) Mitogen-activated protein kinase kinase kinase 10 (EC| 2.7.11.25) (Mixed lineage kinase 2) (Protein kinase MST) Length = 954 Score = 38.5 bits (88), Expect = 0.017 Identities = 30/104 (28%), Positives = 45/104 (43%), Gaps = 3/104 (2%) Frame = -3 Query: 645 YTMKSDVYSFGVVMLELLTGRKPFDSSKPRSEQSLVRWASPQLHDIDALDRMVDPALKGL 466 ++ SDV+SFGV++ ELLTG P+ +IDAL A+ L Sbjct: 280 FSKSSDVWSFGVLLWELLTGEVPY-------------------REIDALAVAYGVAMNKL 320 Query: 465 ---YPAKSLSRFADVLALCVQAEPEFRPPMSEVVQALVRLVQRA 343 P+ FA +L C +P RP +++ L + Q A Sbjct: 321 TLPIPSTCPEPFARLLEECWDPDPHGRPDFGSILKRLEVIEQSA 364
>RAF1_XENLA (P09560) RAF proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (C-RAF) Length = 638 Score = 38.5 bits (88), Expect = 0.017 Identities = 21/71 (29%), Positives = 38/71 (53%) Frame = -3 Query: 645 YTMKSDVYSFGVVMLELLTGRKPFDSSKPRSEQSLVRWASPQLHDIDALDRMVDPALKGL 466 ++ +SDVYS+G+V+ EL+TG P+ + R + + + D+ L + A+K L Sbjct: 516 FSFQSDVYSYGIVLYELMTGELPYSHIRDRDQIIFLVGRGGVVPDLSKLYKNCPKAMKRL 575 Query: 465 YPAKSLSRFAD 433 A S+ + D Sbjct: 576 V-ADSIKKLRD 585
>TXK_HUMAN (P42681) Tyrosine-protein kinase TXK (EC 2.7.10.2)| Length = 527 Score = 38.5 bits (88), Expect = 0.017 Identities = 26/101 (25%), Positives = 49/101 (48%), Gaps = 1/101 (0%) Frame = -3 Query: 648 QYTMKSDVYSFGVVMLELLT-GRKPFDSSKPRSEQSLVRWASPQLHDIDALDRMVDPALK 472 +Y+ KSDV+SFGV+M E+ T G+ PF++ L ++A + + Sbjct: 442 KYSSKSDVWSFGVLMWEVFTEGKMPFENKS-------------NLQVVEA----ISEGFR 484 Query: 471 GLYPAKSLSRFADVLALCVQAEPEFRPPMSEVVQALVRLVQ 349 P + +V+ C +PE RP +E+++A+ + + Sbjct: 485 LYRPHLAPMSIYEVMYSCWHEKPEGRPTFAELLRAVTEIAE 525
>SRC_RSVSE (P63185) Tyrosine-protein kinase transforming protein Src (EC| 2.7.10.2) (p60-Src) (v-Src) (pp60v-src) Length = 525 Score = 38.1 bits (87), Expect = 0.023 Identities = 29/95 (30%), Positives = 49/95 (51%), Gaps = 1/95 (1%) Frame = -3 Query: 648 QYTMKSDVYSFGVVMLELLT-GRKPFDSSKPRSEQSLVRWASPQLHDIDALDRMVDPALK 472 ++T+KSDV+SFG+++ EL T GR P+ P + + + LDR V+ + Sbjct: 437 RFTIKSDVWSFGILLTELTTKGRVPY----------------PGMGNGEVLDR-VERGYR 479 Query: 471 GLYPAKSLSRFADVLALCVQAEPEFRPPMSEVVQA 367 P + D+++ C + +PE RP E +QA Sbjct: 480 MPCPPECPESLHDLMSQCWRRDPEERPTF-EYLQA 513
>YRK_CHICK (Q02977) Proto-oncogene tyrosine-protein kinase Yrk (EC 2.7.10.2)| (p60-Yrk) (Yes-related kinase) Length = 535 Score = 38.1 bits (87), Expect = 0.023 Identities = 26/87 (29%), Positives = 45/87 (51%), Gaps = 1/87 (1%) Frame = -3 Query: 648 QYTMKSDVYSFGVVMLELLT-GRKPFDSSKPRSEQSLVRWASPQLHDIDALDRMVDPALK 472 ++T+KSDV+SFG+++ EL+T GR P+ P +++ + L++ V+ + Sbjct: 440 KFTIKSDVWSFGILLTELVTKGRVPY----------------PGMNNREVLEQ-VERGYR 482 Query: 471 GLYPAKSLSRFADVLALCVQAEPEFRP 391 P DV+ C + EPE RP Sbjct: 483 MQCPGGCPPSLHDVMVQCWKREPEERP 509
>PKNB_BIFLO (Q8G6P9) Probable serine/threonine-protein kinase pknB (EC| 2.7.11.1) Length = 690 Score = 38.1 bits (87), Expect = 0.023 Identities = 22/54 (40%), Positives = 32/54 (59%), Gaps = 2/54 (3%) Frame = -3 Query: 639 MKSDVYSFGVVMLELLTGRKPF--DSSKPRSEQSLVRWASPQLHDIDALDRMVD 484 M+SD+YS G V+ E+LTGR PF DS+ + Q + A+P + L +M D Sbjct: 203 MRSDLYSAGCVLYEMLTGRPPFTGDSAVAIAYQHVSEVATPPSAAVPGLPKMWD 256
>RAF1_RAT (P11345) RAF proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (Raf-1) (C-RAF) (cRaf) Length = 648 Score = 38.1 bits (87), Expect = 0.023 Identities = 27/97 (27%), Positives = 48/97 (49%), Gaps = 3/97 (3%) Frame = -3 Query: 645 YTMKSDVYSFGVVMLELLTGRKPFDSSKPRSEQSLV---RWASPQLHDIDALDRMVDPAL 475 ++ +SDVYS+G+V+ EL+TG P+ R + + +ASP D+ L + A+ Sbjct: 525 FSFQSDVYSYGIVLYELMTGELPYSHINNRDQIIFMVGRGYASP---DLSRLYKNCPKAM 581 Query: 474 KGLYPAKSLSRFADVLALCVQAEPEFRPPMSEVVQAL 364 K L +A CV+ E RP +++ ++ Sbjct: 582 KRL------------VADCVKKVKEERPLFPQILSSI 606
>RAF1_HUMAN (P04049) RAF proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (Raf-1) (C-RAF) (cRaf) Length = 648 Score = 38.1 bits (87), Expect = 0.023 Identities = 27/97 (27%), Positives = 48/97 (49%), Gaps = 3/97 (3%) Frame = -3 Query: 645 YTMKSDVYSFGVVMLELLTGRKPFDSSKPRSEQSLV---RWASPQLHDIDALDRMVDPAL 475 ++ +SDVYS+G+V+ EL+TG P+ R + + +ASP D+ L + A+ Sbjct: 525 FSFQSDVYSYGIVLYELMTGELPYSHINNRDQIIFMVGRGYASP---DLSKLYKNCPKAM 581 Query: 474 KGLYPAKSLSRFADVLALCVQAEPEFRPPMSEVVQAL 364 K L +A CV+ E RP +++ ++ Sbjct: 582 KRL------------VADCVKKVKEERPLFPQILSSI 606
>AL2S2_HUMAN (Q9C0K7) Serine/threonine-protein kinase ALS2CR2 (EC 2.7.11.1)| (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 2 protein) (ILP-interacting protein) (CALS-21) Length = 418 Score = 38.1 bits (87), Expect = 0.023 Identities = 33/126 (26%), Positives = 51/126 (40%), Gaps = 35/126 (27%) Frame = -3 Query: 645 YTMKSDVYSFGVVMLELLTGRKPFD----------------------SSKPRSEQSLVR- 535 Y +KSD+YS G+ EL +G+ PF S P+SE + Sbjct: 245 YNVKSDIYSVGITACELASGQVPFQDMHRTQMLLQKLKGPPYSPLDISIFPQSESRMKNS 304 Query: 534 ------------WASPQLHDIDALDRMVDPALKGLYPAKSLSRFADVLALCVQAEPEFRP 391 S H +++ DR+ P+ K PA F ++ LC+Q +PE RP Sbjct: 305 QSGVDSGIGESVLVSSGTHTVNS-DRLHTPSSKTFSPA-----FFSLVQLCLQQDPEKRP 358 Query: 390 PMSEVV 373 S ++ Sbjct: 359 SASSLL 364
>ITK_HUMAN (Q08881) Tyrosine-protein kinase ITK/TSK (EC 2.7.10.2)| (T-cell-specific kinase) (Tyrosine-protein kinase Lyk) (Kinase EMT) Length = 620 Score = 37.7 bits (86), Expect = 0.030 Identities = 28/101 (27%), Positives = 50/101 (49%), Gaps = 1/101 (0%) Frame = -3 Query: 648 QYTMKSDVYSFGVVMLELLT-GRKPFDSSKPRSEQSLVRWASPQLHDIDALDRMVDPALK 472 +Y+ KSDV+SFGV+M E+ + G+ P+++ RS +V DI R+ P L Sbjct: 534 RYSSKSDVWSFGVLMWEVFSEGKIPYEN---RSNSEVV-------EDISTGFRLYKPRLA 583 Query: 471 GLYPAKSLSRFADVLALCVQAEPEFRPPMSEVVQALVRLVQ 349 + + ++ C + PE RP S +++ L + + Sbjct: 584 STHVYQIMNH-------CWKERPEDRPAFSRLLRQLAEIAE 617
>SRC_RSVSA (P00524) Tyrosine-protein kinase transforming protein Src (EC| 2.7.10.2) (p60-Src) (v-Src) (pp60v-src) Length = 525 Score = 37.7 bits (86), Expect = 0.030 Identities = 29/95 (30%), Positives = 48/95 (50%), Gaps = 1/95 (1%) Frame = -3 Query: 648 QYTMKSDVYSFGVVMLELLT-GRKPFDSSKPRSEQSLVRWASPQLHDIDALDRMVDPALK 472 ++T+KSDV+SFG+++ EL T GR P+ P + + + LDR V+ + Sbjct: 437 RFTIKSDVWSFGILLTELTTKGRVPY----------------PGMGNGEVLDR-VERGYR 479 Query: 471 GLYPAKSLSRFADVLALCVQAEPEFRPPMSEVVQA 367 P + D++ C + +PE RP E +QA Sbjct: 480 MPCPPECPESLHDLMCQCWRRDPEERPTF-EYLQA 513
>SRC_AVISR (P00525) Tyrosine-protein kinase transforming protein Src (EC| 2.7.10.2) (p60-Src) (v-Src) (pp60v-src) Length = 525 Score = 37.7 bits (86), Expect = 0.030 Identities = 29/95 (30%), Positives = 48/95 (50%), Gaps = 1/95 (1%) Frame = -3 Query: 648 QYTMKSDVYSFGVVMLELLT-GRKPFDSSKPRSEQSLVRWASPQLHDIDALDRMVDPALK 472 ++T+KSDV+SFG+++ EL T GR P+ P + + + LDR V+ + Sbjct: 437 RFTIKSDVWSFGILLTELTTKGRVPY----------------PGMGNGEVLDR-VERGYR 479 Query: 471 GLYPAKSLSRFADVLALCVQAEPEFRPPMSEVVQA 367 P + D++ C + +PE RP E +QA Sbjct: 480 MPCPPECPESLHDLMCQCWRRDPEERPTF-EYLQA 513
>VGFR2_BRARE (Q8AXB3) Vascular endothelial growth factor receptor 2 precursor (EC| 2.7.10.1) (VEGFR-2) (Receptor tyrosine kinase flk-1) Length = 1302 Score = 37.7 bits (86), Expect = 0.030 Identities = 29/100 (29%), Positives = 43/100 (43%), Gaps = 1/100 (1%) Frame = -3 Query: 645 YTMKSDVYSFGVVMLELLT-GRKPFDSSKPRSEQSLVRWASPQLHDIDALDRMVDPALKG 469 YT +SDV+SFGV+M E+ + G P+ P LH + + + Sbjct: 1057 YTTQSDVWSFGVLMWEIFSLGASPY----------------PGLHIDEEFCCRLKEGTRM 1100 Query: 468 LYPAKSLSRFADVLALCVQAEPEFRPPMSEVVQALVRLVQ 349 P S S + C EP RP +E+V+ L L+Q Sbjct: 1101 KAPEYSSSEIYQTMLDCWHGEPSQRPTFTELVERLGDLLQ 1140
>KIT_BOVIN (P43481) Mast/stem cell growth factor receptor precursor (EC| 2.7.10.1) (SCFR) (Proto-oncogene tyrosine-protein kinase Kit) (c-kit) Length = 977 Score = 37.7 bits (86), Expect = 0.030 Identities = 23/102 (22%), Positives = 45/102 (44%), Gaps = 1/102 (0%) Frame = -3 Query: 645 YTMKSDVYSFGVVMLELLT-GRKPFDSSKPRSEQSLVRWASPQLHDIDALDRMVDPALKG 469 YT +SDV+S+G+ + EL + G P+ S+ +M+ + Sbjct: 847 YTFESDVWSYGIFLWELFSLGSSPYPGMPVDSK----------------FYKMIKEGFRM 890 Query: 468 LYPAKSLSRFADVLALCVQAEPEFRPPMSEVVQALVRLVQRA 343 L P + + D++ C A+P RP ++VQ + + + + Sbjct: 891 LSPEHAPAEMYDIMKTCWDADPLKRPTFKQIVQLIEKQISES 932
>SRC_RAT (Q9WUD9) Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2)| (p60-Src) (c-Src) (pp60c-src) Length = 535 Score = 37.7 bits (86), Expect = 0.030 Identities = 29/97 (29%), Positives = 49/97 (50%), Gaps = 1/97 (1%) Frame = -3 Query: 648 QYTMKSDVYSFGVVMLELLT-GRKPFDSSKPRSEQSLVRWASPQLHDIDALDRMVDPALK 472 ++T+KSDV+SFG+++ EL T GR P+ P + + + LD+ V+ + Sbjct: 440 RFTIKSDVWSFGILLTELTTKGRVPY----------------PGMVNREVLDQ-VERGYR 482 Query: 471 GLYPAKSLSRFADVLALCVQAEPEFRPPMSEVVQALV 361 P + D++ C + EPE RP E +QA + Sbjct: 483 MPCPPECPESLHDLMCQCWRKEPEERPTF-EYLQAFL 518
>SRC_HUMAN (P12931) Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2)| (p60-Src) (c-Src) (pp60c-src) Length = 535 Score = 37.7 bits (86), Expect = 0.030 Identities = 29/97 (29%), Positives = 49/97 (50%), Gaps = 1/97 (1%) Frame = -3 Query: 648 QYTMKSDVYSFGVVMLELLT-GRKPFDSSKPRSEQSLVRWASPQLHDIDALDRMVDPALK 472 ++T+KSDV+SFG+++ EL T GR P+ P + + + LD+ V+ + Sbjct: 440 RFTIKSDVWSFGILLTELTTKGRVPY----------------PGMVNREVLDQ-VERGYR 482 Query: 471 GLYPAKSLSRFADVLALCVQAEPEFRPPMSEVVQALV 361 P + D++ C + EPE RP E +QA + Sbjct: 483 MPCPPECPESLHDLMCQCWRKEPEERPTF-EYLQAFL 518
>KIT_CAPHI (Q28317) Mast/stem cell growth factor receptor precursor (EC| 2.7.10.1) (SCFR) (Proto-oncogene tyrosine-protein kinase Kit) (c-kit) Length = 978 Score = 37.7 bits (86), Expect = 0.030 Identities = 23/102 (22%), Positives = 45/102 (44%), Gaps = 1/102 (0%) Frame = -3 Query: 645 YTMKSDVYSFGVVMLELLT-GRKPFDSSKPRSEQSLVRWASPQLHDIDALDRMVDPALKG 469 YT +SDV+S+G+ + EL + G P+ S+ +M+ + Sbjct: 848 YTFESDVWSYGIFLWELFSLGSSPYPGMPVDSK----------------FYKMIKEGFRM 891 Query: 468 LYPAKSLSRFADVLALCVQAEPEFRPPMSEVVQALVRLVQRA 343 L P + + D++ C A+P RP ++VQ + + + + Sbjct: 892 LSPEHAPAEMYDIMKTCWDADPLKRPTFKQIVQLIEKQISES 933
>KIT_HUMAN (P10721) Mast/stem cell growth factor receptor precursor (EC| 2.7.10.1) (SCFR) (Proto-oncogene tyrosine-protein kinase Kit) (c-kit) (CD117 antigen) Length = 976 Score = 37.7 bits (86), Expect = 0.030 Identities = 23/102 (22%), Positives = 45/102 (44%), Gaps = 1/102 (0%) Frame = -3 Query: 645 YTMKSDVYSFGVVMLELLT-GRKPFDSSKPRSEQSLVRWASPQLHDIDALDRMVDPALKG 469 YT +SDV+S+G+ + EL + G P+ S+ +M+ + Sbjct: 846 YTFESDVWSYGIFLWELFSLGSSPYPGMPVDSK----------------FYKMIKEGFRM 889 Query: 468 LYPAKSLSRFADVLALCVQAEPEFRPPMSEVVQALVRLVQRA 343 L P + + D++ C A+P RP ++VQ + + + + Sbjct: 890 LSPEHAPAEMYDIMKTCWDADPLKRPTFKQIVQLIEKQISES 931
>EPHA2_HUMAN (P29317) Ephrin type-A receptor 2 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor ECK) (Epithelial cell kinase) Length = 976 Score = 37.7 bits (86), Expect = 0.030 Identities = 28/113 (24%), Positives = 54/113 (47%), Gaps = 1/113 (0%) Frame = -3 Query: 648 QYTMKSDVYSFGVVMLELLT-GRKPFDSSKPRSEQSLVRWASPQLHDIDALDRMVDPALK 472 ++T SDV+SFG+VM E++T G +P+ W +L + + + + ++ + Sbjct: 793 KFTSASDVWSFGIVMWEVMTYGERPY-------------W---ELSNHEVM-KAINDGFR 835 Query: 471 GLYPAKSLSRFADVLALCVQAEPEFRPPMSEVVQALVRLVQRANMTKKMLDGD 313 P S ++ C Q E RP +++V L +L++ + K + D D Sbjct: 836 LPTPMDCPSAIYQLMMQCWQQERARRPKFADIVSILDKLIRAPDSLKTLADFD 888
>PKN6_MYXXA (P54738) Serine/threonine-protein kinase pkn6 (EC 2.7.11.1)| Length = 710 Score = 37.7 bits (86), Expect = 0.030 Identities = 29/77 (37%), Positives = 43/77 (55%), Gaps = 7/77 (9%) Frame = -3 Query: 630 DVYSFGVVMLELLTGRKPFDSSKPRSEQSLVRW-----ASPQLHDID-ALDRMVDPALKG 469 DVY+ GVV+ ELLTG++PFD++ S + + S + D+ AL +++D AL Sbjct: 201 DVYALGVVLYELLTGKRPFDATTDVSVMQAILFESFIPVSARRPDVPVALQQVLDKAL-- 258 Query: 468 LYPAKSLS-RFADVLAL 421 AK R+AD AL Sbjct: 259 ---AKDRERRYADCRAL 272
>TNI3K_RAT (Q7TQP6) Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1)| (TNNI3-interacting kinase) (Cardiac ankyrin repeat kinase) Length = 834 Score = 37.7 bits (86), Expect = 0.030 Identities = 30/98 (30%), Positives = 44/98 (44%), Gaps = 3/98 (3%) Frame = -3 Query: 648 QYTMKSDVYSFGVVMLELLTGRKPFDSSKPRSEQSLVRWASPQLHDIDALDRMVDPALKG 469 +YT+K+DV+S+ + + ELLTG PF KP + + D A Sbjct: 640 RYTIKADVFSYSLCLWELLTGEIPFAHLKPAAAAA-------------------DMAYHH 680 Query: 468 LYPAKSLSRFADVLALCVQ---AEPEFRPPMSEVVQAL 364 + P S + +L ++ A PE RP SEVV L Sbjct: 681 IRPPIGYSIPKPISSLLIRGWNACPEGRPEFSEVVSKL 718
>ARAF_PIG (O19004) A-Raf proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (A-Raf-1) Length = 606 Score = 37.7 bits (86), Expect = 0.030 Identities = 26/101 (25%), Positives = 49/101 (48%) Frame = -3 Query: 645 YTMKSDVYSFGVVMLELLTGRKPFDSSKPRSEQSLVRWASPQLHDIDALDRMVDPALKGL 466 Y+ +SDVY++GVV+ EL+TG P+ R + + D+ + A++ L Sbjct: 486 YSFQSDVYAYGVVLYELMTGSLPYSHIGSRDQIIFMVGRGYLSPDLSKISSNCPKAMRRL 545 Query: 465 YPAKSLSRFADVLALCVQAEPEFRPPMSEVVQALVRLVQRA 343 L+ C++ + E RP +++ A + L+QR+ Sbjct: 546 ------------LSDCLKFQREERPLFPQIL-ATIELLQRS 573
>SRC_MOUSE (P05480) Neuronal proto-oncogene tyrosine-protein kinase Src (EC| 2.7.10.2) (p60-Src) (c-Src) (pp60c-src) Length = 540 Score = 37.7 bits (86), Expect = 0.030 Identities = 29/97 (29%), Positives = 49/97 (50%), Gaps = 1/97 (1%) Frame = -3 Query: 648 QYTMKSDVYSFGVVMLELLT-GRKPFDSSKPRSEQSLVRWASPQLHDIDALDRMVDPALK 472 ++T+KSDV+SFG+++ EL T GR P+ P + + + LD+ V+ + Sbjct: 445 RFTIKSDVWSFGILLTELTTKGRVPY----------------PGMVNREVLDQ-VERGYR 487 Query: 471 GLYPAKSLSRFADVLALCVQAEPEFRPPMSEVVQALV 361 P + D++ C + EPE RP E +QA + Sbjct: 488 MPCPPECPESLHDLMCQCWRKEPEERPTF-EYLQAFL 523
>SRC_RSVPA (P31693) Tyrosine-protein kinase transforming protein Src (EC| 2.7.10.2) (p60-Src) (v-Src) (pp60v-src) Length = 522 Score = 37.4 bits (85), Expect = 0.039 Identities = 29/95 (30%), Positives = 48/95 (50%), Gaps = 1/95 (1%) Frame = -3 Query: 648 QYTMKSDVYSFGVVMLELLT-GRKPFDSSKPRSEQSLVRWASPQLHDIDALDRMVDPALK 472 ++T+KSDV+SFG+++ EL T GR P+ P + + + LDR V+ + Sbjct: 434 RFTIKSDVWSFGILLTELTTKGRVPY----------------PGMVNGEVLDR-VERGYR 476 Query: 471 GLYPAKSLSRFADVLALCVQAEPEFRPPMSEVVQA 367 P + D++ C + +PE RP E +QA Sbjct: 477 MPCPPECPESLHDLMCQCWRKDPEERPTF-EYLQA 510
>SRC_RSVH1 (P25020) Tyrosine-protein kinase transforming protein Src (EC| 2.7.10.2) (p60-Src) (v-Src) (pp60v-src) Length = 525 Score = 37.4 bits (85), Expect = 0.039 Identities = 26/87 (29%), Positives = 45/87 (51%), Gaps = 1/87 (1%) Frame = -3 Query: 648 QYTMKSDVYSFGVVMLELLT-GRKPFDSSKPRSEQSLVRWASPQLHDIDALDRMVDPALK 472 ++T+KSDV+SFG+++ EL T GR P+ P + + + LD+ V+ A + Sbjct: 437 RFTIKSDVWSFGILLTELTTKGRVPY----------------PGMVNREVLDQ-VERAYR 479 Query: 471 GLYPAKSLSRFADVLALCVQAEPEFRP 391 P + D++ C + +PE RP Sbjct: 480 MPCPPECPESLHDLMCQCWRKDPEERP 506
>KIT_FELCA (Q28889) Mast/stem cell growth factor receptor precursor (EC| 2.7.10.1) (SCFR) (Proto-oncogene tyrosine-protein kinase Kit) (c-kit) Length = 978 Score = 37.4 bits (85), Expect = 0.039 Identities = 23/99 (23%), Positives = 44/99 (44%), Gaps = 1/99 (1%) Frame = -3 Query: 645 YTMKSDVYSFGVVMLELLT-GRKPFDSSKPRSEQSLVRWASPQLHDIDALDRMVDPALKG 469 YT +SDV+S+G+ + EL + G P+ S+ +M+ + Sbjct: 847 YTFESDVWSYGIFLWELFSLGSSPYPGMPVDSK----------------FYKMIKEGFRM 890 Query: 468 LYPAKSLSRFADVLALCVQAEPEFRPPMSEVVQALVRLV 352 L P + + D++ C A+P RP ++VQ + + + Sbjct: 891 LSPEHAPAEMYDIMKTCWDADPLKRPTFKQIVQLIEKQI 929
>PKN5_MYXXA (P54737) Serine/threonine-protein kinase pkn5 (EC 2.7.11.1)| Length = 380 Score = 37.4 bits (85), Expect = 0.039 Identities = 14/26 (53%), Positives = 21/26 (80%) Frame = -3 Query: 636 KSDVYSFGVVMLELLTGRKPFDSSKP 559 ++D+YS GV++ ELL+GR PFD+ P Sbjct: 301 RADLYSLGVILYELLSGRPPFDAKTP 326
>KIT_CANFA (O97799) Mast/stem cell growth factor receptor precursor (EC| 2.7.10.1) (SCFR) (Proto-oncogene tyrosine-protein kinase Kit) (c-kit) Length = 975 Score = 37.4 bits (85), Expect = 0.039 Identities = 23/99 (23%), Positives = 44/99 (44%), Gaps = 1/99 (1%) Frame = -3 Query: 645 YTMKSDVYSFGVVMLELLT-GRKPFDSSKPRSEQSLVRWASPQLHDIDALDRMVDPALKG 469 YT +SDV+S+G+ + EL + G P+ S+ +M+ + Sbjct: 845 YTFESDVWSYGIFLWELFSLGSSPYPGMPVDSK----------------FYKMIKEGFRM 888 Query: 468 LYPAKSLSRFADVLALCVQAEPEFRPPMSEVVQALVRLV 352 L P + + D++ C A+P RP ++VQ + + + Sbjct: 889 LSPEHAPAEMYDIMKTCWDADPLKRPTFKQIVQLIEKQI 927
>SRK1_SPOLA (P42686) Tyrosine-protein kinase isoform SRK1 (EC 2.7.10.2)| Length = 505 Score = 37.4 bits (85), Expect = 0.039 Identities = 25/87 (28%), Positives = 45/87 (51%), Gaps = 1/87 (1%) Frame = -3 Query: 648 QYTMKSDVYSFGVVMLELLT-GRKPFDSSKPRSEQSLVRWASPQLHDIDALDRMVDPALK 472 ++T+KSDV+SFGVV+ E++T GR P+ P + + + L++ + + Sbjct: 411 RFTIKSDVWSFGVVLYEIITYGRFPY----------------PGMTNPEVLEK-IQQNYR 453 Query: 471 GLYPAKSLSRFADVLALCVQAEPEFRP 391 PA +F D++ C + +P RP Sbjct: 454 MPCPANCPKQFHDIMLDCWREDPASRP 480
>UFO_MOUSE (Q00993) Tyrosine-protein kinase receptor UFO precursor (EC| 2.7.10.1) (Adhesion-related kinase) Length = 888 Score = 37.4 bits (85), Expect = 0.039 Identities = 28/95 (29%), Positives = 43/95 (45%), Gaps = 1/95 (1%) Frame = -3 Query: 645 YTMKSDVYSFGVVMLELLT-GRKPFDSSKPRSEQSLVRWASPQLHDIDALDRMVDPALKG 469 YT KSDV+SFGV M E+ T G+ P+ + +R + +D LD G Sbjct: 720 YTSKSDVWSFGVTMWEIATRGQTPYPGVENSEIYDYLRQGNRLKQPVDFLD--------G 771 Query: 468 LYPAKSLSRFADVLALCVQAEPEFRPPMSEVVQAL 364 LY +++ C + P RP +E+ + L Sbjct: 772 LY---------SLMSRCWELNPRDRPSFAELREDL 797
>RAF1_CHICK (P05625) RAF proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (RAF-1) (C-RAF) (MIL proto-oncogene serine/threonine-protein kinase) (C-MIL) Length = 647 Score = 37.4 bits (85), Expect = 0.039 Identities = 22/66 (33%), Positives = 36/66 (54%), Gaps = 8/66 (12%) Frame = -3 Query: 645 YTMKSDVYSFGVVMLELLTGRKPFDSSKPRSEQSLV---RWASPQLHDI-----DALDRM 490 ++ +SDVYS+G+V+ EL+TG P+ R + + +ASP L + A+ R+ Sbjct: 525 FSFQSDVYSYGIVLYELMTGELPYSHINNRDQIIFMVGRGYASPDLSKLYKNCPKAMKRL 584 Query: 489 VDPALK 472 V LK Sbjct: 585 VADCLK 590
>UFO_HUMAN (P30530) Tyrosine-protein kinase receptor UFO precursor (EC| 2.7.10.1) (AXL oncogene) Length = 887 Score = 37.0 bits (84), Expect = 0.051 Identities = 28/95 (29%), Positives = 43/95 (45%), Gaps = 1/95 (1%) Frame = -3 Query: 645 YTMKSDVYSFGVVMLELLT-GRKPFDSSKPRSEQSLVRWASPQLHDIDALDRMVDPALKG 469 YT KSDV+SFGV M E+ T G+ P+ + +R + D LD G Sbjct: 719 YTSKSDVWSFGVTMWEIATRGQTPYPGVENSEIYDYLRQGNRLKQPADCLD--------G 770 Query: 468 LYPAKSLSRFADVLALCVQAEPEFRPPMSEVVQAL 364 LY +++ C + P+ RP +E+ + L Sbjct: 771 LYA---------LMSRCWELNPQDRPSFTELREDL 796
>TNI3K_HUMAN (Q59H18) Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1)| (TNNI3-interacting kinase) (Cardiac ankyrin repeat kinase) Length = 936 Score = 37.0 bits (84), Expect = 0.051 Identities = 29/98 (29%), Positives = 44/98 (44%), Gaps = 3/98 (3%) Frame = -3 Query: 648 QYTMKSDVYSFGVVMLELLTGRKPFDSSKPRSEQSLVRWASPQLHDIDALDRMVDPALKG 469 +YT+K+DV+S+ + + E+LTG PF KP + + D A Sbjct: 742 RYTIKADVFSYALCLWEILTGEIPFAHLKPAAAAA-------------------DMAYHH 782 Query: 468 LYPAKSLSRFADVLALCVQ---AEPEFRPPMSEVVQAL 364 + P S + +L ++ A PE RP SEVV L Sbjct: 783 IRPPIGYSIPKPISSLLIRGWNACPEGRPEFSEVVMKL 820
>MATK_HUMAN (P42679) Megakaryocyte-associated tyrosine-protein kinase (EC| 2.7.10.2) (Tyrosine-protein kinase CTK) (Protein kinase HYL) (Hematopoietic consensus tyrosine-lacking kinase) Length = 507 Score = 37.0 bits (84), Expect = 0.051 Identities = 29/124 (23%), Positives = 55/124 (44%), Gaps = 1/124 (0%) Frame = -3 Query: 648 QYTMKSDVYSFGVVMLELLT-GRKPFDSSKPRSEQSLVRWASPQLHDIDALDRMVDPALK 472 ++T KSDV+SFGV++ E+ + GR P+ P++ + + V+ + Sbjct: 400 KFTSKSDVWSFGVLLWEVFSYGRAPY----------------PKM-SLKEVSEAVEKGYR 442 Query: 471 GLYPAKSLSRFADVLALCVQAEPEFRPPMSEVVQALVRLVQRANMTKKMLDGDASRRGDD 292 P +++ C +AEP RPP ++ + L R ++ A + DA Sbjct: 443 MEPPEGCPGPVHVLMSSCWEAEPARRPPFRKLAEKLARELRSAGAPASVSGQDADGSTSP 502 Query: 291 QDQD 280 + Q+ Sbjct: 503 RSQE 506
>EPHA2_MOUSE (Q03145) Ephrin type-A receptor 2 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor ECK) (Epithelial cell kinase) (MPK-5) (SEK-2) Length = 977 Score = 37.0 bits (84), Expect = 0.051 Identities = 27/113 (23%), Positives = 54/113 (47%), Gaps = 1/113 (0%) Frame = -3 Query: 648 QYTMKSDVYSFGVVMLELLT-GRKPFDSSKPRSEQSLVRWASPQLHDIDALDRMVDPALK 472 ++T SDV+S+G+VM E++T G +P+ W +L + + + + ++ + Sbjct: 794 KFTSASDVWSYGIVMWEVMTYGERPY-------------W---ELSNHEVM-KAINDGFR 836 Query: 471 GLYPAKSLSRFADVLALCVQAEPEFRPPMSEVVQALVRLVQRANMTKKMLDGD 313 P S ++ C Q E RP +++V L +L++ + K + D D Sbjct: 837 LPTPMDCPSAIYQLMMQCWQQERSRRPKFADIVSILDKLIRAPDSLKTLADFD 889
>UNC51_CAEEL (Q23023) Serine/threonine-protein kinase unc-51 (EC 2.7.11.1)| (Uncoordinated protein 51) Length = 856 Score = 37.0 bits (84), Expect = 0.051 Identities = 17/58 (29%), Positives = 28/58 (48%), Gaps = 11/58 (18%) Frame = -3 Query: 648 QYTMKSDVYSFGVVMLELLTGRKPFDSSKP-----------RSEQSLVRWASPQLHDI 508 QY K+D++S G ++ + LTG+ PF + P ++ W SP L D+ Sbjct: 194 QYDAKADLWSIGTILFQCLTGKAPFVAQTPPQLKAYYEKTRELRPNIPEWCSPNLRDL 251
>PKNA2_BIFLO (Q8G4G1) Probable serine/threonine-protein kinase pknA2 (EC| 2.7.11.1) Length = 757 Score = 37.0 bits (84), Expect = 0.051 Identities = 15/30 (50%), Positives = 21/30 (70%) Frame = -3 Query: 648 QYTMKSDVYSFGVVMLELLTGRKPFDSSKP 559 Q T + D+YS G++ E+LTG+ PFDS P Sbjct: 192 QATAQGDLYSVGIMAWEMLTGKVPFDSDNP 221
>PKNS_MYCPN (P75524) Putative serine/threonine-protein kinase (EC 2.7.11.1)| Length = 389 Score = 37.0 bits (84), Expect = 0.051 Identities = 16/39 (41%), Positives = 27/39 (69%), Gaps = 1/39 (2%) Frame = -3 Query: 642 TMKSDVYSFGVVMLELLTGRKPFDSS-KPRSEQSLVRWA 529 T++ D+YS GV++ E+L GR PF+ S P+ E+ ++ A Sbjct: 234 TVQYDIYSLGVILFEMLVGRVPFNKSIDPKKERETIQKA 272
>M3K11_HUMAN (Q16584) Mitogen-activated protein kinase kinase kinase 11 (EC| 2.7.11.25) (Mixed lineage kinase 3) (Src-homology 3 domain-containing proline-rich kinase) Length = 847 Score = 37.0 bits (84), Expect = 0.051 Identities = 29/100 (29%), Positives = 43/100 (43%), Gaps = 3/100 (3%) Frame = -3 Query: 645 YTMKSDVYSFGVVMLELLTGRKPFDSSKPRSEQSLVRWASPQLHDIDALDRMVDPALKGL 466 ++ SDV+SFGV++ ELLTG P+ ID L A+ L Sbjct: 299 FSKGSDVWSFGVLLWELLTGEVPY-------------------RGIDCLAVAYGVAVNKL 339 Query: 465 ---YPAKSLSRFADVLALCVQAEPEFRPPMSEVVQALVRL 355 P+ FA ++A C +P RP + ++Q L L Sbjct: 340 TLPIPSTCPEPFAQLMADCWAQDPHRRPDFASILQQLEAL 379
>KIT_MOUSE (P05532) Mast/stem cell growth factor receptor precursor (EC| 2.7.10.1) (SCFR) (Proto-oncogene tyrosine-protein kinase Kit) (c-kit) Length = 975 Score = 37.0 bits (84), Expect = 0.051 Identities = 24/99 (24%), Positives = 44/99 (44%), Gaps = 1/99 (1%) Frame = -3 Query: 645 YTMKSDVYSFGVVMLELLT-GRKPFDSSKPRSEQSLVRWASPQLHDIDALDRMVDPALKG 469 YT +SDV+S+G+ + EL + G P+ S+ +M+ + Sbjct: 844 YTFESDVWSYGIFLWELFSLGSSPYPGMPVDSK----------------FYKMIKEGFRM 887 Query: 468 LYPAKSLSRFADVLALCVQAEPEFRPPMSEVVQALVRLV 352 + P + + DV+ C A+P RP +VVQ + + + Sbjct: 888 VSPEHAPAEMYDVMKTCWDADPLKRPTFKQVVQLIEKQI 926
>RYK_AVIR3 (P33497) Tyrosine-protein kinase transforming protein RYK (EC| 2.7.10.1) Length = 442 Score = 37.0 bits (84), Expect = 0.051 Identities = 27/99 (27%), Positives = 45/99 (45%) Frame = -3 Query: 645 YTMKSDVYSFGVVMLELLTGRKPFDSSKPRSEQSLVRWASPQLHDIDALDRMVDPALKGL 466 YT KSDV++FGV M E+ T + + + Q H+I + + Sbjct: 235 YTTKSDVWAFGVTMWEIAT-------------RGMTPYPGVQNHEI---YEYLFHGQRLK 278 Query: 465 YPAKSLSRFADVLALCVQAEPEFRPPMSEVVQALVRLVQ 349 P L D+++ C +AEP RP S++ L +L++ Sbjct: 279 KPENCLDELYDIMSSCWRAEPADRPTFSQLKVHLEKLLE 317
>KIT_FSVHZ (P04048) Tyrosine-protein kinase transforming protein kit (EC| 2.7.10.1) Length = 370 Score = 37.0 bits (84), Expect = 0.051 Identities = 23/95 (24%), Positives = 42/95 (44%), Gaps = 1/95 (1%) Frame = -3 Query: 645 YTMKSDVYSFGVVMLELLT-GRKPFDSSKPRSEQSLVRWASPQLHDIDALDRMVDPALKG 469 YT +SDV+S+G+ + EL + G P+ S+ +M+ + Sbjct: 284 YTFESDVWSYGIFLWELFSLGSSPYPGMPVDSK----------------FYKMIKEGFRM 327 Query: 468 LYPAKSLSRFADVLALCVQAEPEFRPPMSEVVQAL 364 L P + + D++ C A+P RP ++VQ + Sbjct: 328 LSPEHAPAEMYDIMKTCWDADPLKRPTFKQIVQLI 362
>PKN2_CLOAB (Q97IC2) Probable serine/threonine protein kinase CAC1728 (EC| 2.7.11.1) Length = 657 Score = 37.0 bits (84), Expect = 0.051 Identities = 13/28 (46%), Positives = 22/28 (78%) Frame = -3 Query: 636 KSDVYSFGVVMLELLTGRKPFDSSKPRS 553 ++D+YSFG+V+ E+ TG+ P+D+ P S Sbjct: 189 RTDIYSFGIVLYEMATGKVPYDADTPVS 216
>ARAF_HUMAN (P10398) A-Raf proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (A-raf-1) (Proto-oncogene Pks) Length = 606 Score = 37.0 bits (84), Expect = 0.051 Identities = 26/101 (25%), Positives = 49/101 (48%) Frame = -3 Query: 645 YTMKSDVYSFGVVMLELLTGRKPFDSSKPRSEQSLVRWASPQLHDIDALDRMVDPALKGL 466 Y+ +SDVY++GVV+ EL+TG P+ R + + D+ + A++ L Sbjct: 486 YSFQSDVYAYGVVLYELMTGSLPYSHIGCRDQIIFMVGRGYLSPDLSKISSNCPKAMRRL 545 Query: 465 YPAKSLSRFADVLALCVQAEPEFRPPMSEVVQALVRLVQRA 343 L+ C++ + E RP +++ A + L+QR+ Sbjct: 546 ------------LSDCLKFQREERPLFPQIL-ATIELLQRS 573
>MATK_RAT (P41243) Megakaryocyte-associated tyrosine-protein kinase (EC| 2.7.10.2) (Tyrosine-protein kinase CTK) (Protein kinase BATK) Length = 467 Score = 37.0 bits (84), Expect = 0.051 Identities = 31/124 (25%), Positives = 56/124 (45%), Gaps = 5/124 (4%) Frame = -3 Query: 648 QYTMKSDVYSFGVVMLELLT-GRKPFDSSKPRSEQSLVRWASPQLHDIDALDRMVDPALK 472 +++ KSDV+SFGV++ E+ + GR P+ P+ V A + + ++ D P Sbjct: 360 RFSSKSDVWSFGVLLWEVFSYGRAPY----PKMSLKEVSEAVEKGYRMEPPDSCPGPV-- 413 Query: 471 GLYPAKSLSRFADVLALCVQAEPEFRPPMSEVVQALVRLVQRANMTK----KMLDGDASR 304 ++ C +AEP RPP ++V+ L R ++ + + +G A Sbjct: 414 -----------HTLMGSCWEAEPSRRPPFRKIVEKLGRELRSVGVAAPAGGQEAEGSAPT 462 Query: 303 RGDD 292 R D Sbjct: 463 RSQD 466
>SRC_AVIST (P14085) Tyrosine-protein kinase transforming protein Src (EC| 2.7.10.2) (p60-Src) (v-Src) (pp60v-src) Length = 556 Score = 36.6 bits (83), Expect = 0.066 Identities = 28/97 (28%), Positives = 49/97 (50%), Gaps = 1/97 (1%) Frame = -3 Query: 648 QYTMKSDVYSFGVVMLELLT-GRKPFDSSKPRSEQSLVRWASPQLHDIDALDRMVDPALK 472 ++T+KSDV+SFG+++ EL T GR P+ P + + + LD+ V+ + Sbjct: 437 RFTIKSDVWSFGILLTELTTKGRVPY----------------PGMVNREVLDQ-VERGYR 479 Query: 471 GLYPAKSLSRFADVLALCVQAEPEFRPPMSEVVQALV 361 P + D++ C + +PE RP E +QA + Sbjct: 480 MPCPPECPESLHDLMCQCWRKDPEERPTF-EYLQAFL 515
>SRC_CHICK (P00523) Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2)| (p60-Src) (c-Src) (pp60c-src) Length = 532 Score = 36.6 bits (83), Expect = 0.066 Identities = 28/97 (28%), Positives = 49/97 (50%), Gaps = 1/97 (1%) Frame = -3 Query: 648 QYTMKSDVYSFGVVMLELLT-GRKPFDSSKPRSEQSLVRWASPQLHDIDALDRMVDPALK 472 ++T+KSDV+SFG+++ EL T GR P+ P + + + LD+ V+ + Sbjct: 437 RFTIKSDVWSFGILLTELTTKGRVPY----------------PGMVNREVLDQ-VERGYR 479 Query: 471 GLYPAKSLSRFADVLALCVQAEPEFRPPMSEVVQALV 361 P + D++ C + +PE RP E +QA + Sbjct: 480 MPCPPECPESLHDLMCQCWRKDPEERPTF-EYLQAFL 515
>SRC_AVISS (P14084) Tyrosine-protein kinase transforming protein Src (EC| 2.7.10.2) (p60-Src) (v-Src) (pp60v-src) Length = 567 Score = 36.6 bits (83), Expect = 0.066 Identities = 28/97 (28%), Positives = 49/97 (50%), Gaps = 1/97 (1%) Frame = -3 Query: 648 QYTMKSDVYSFGVVMLELLT-GRKPFDSSKPRSEQSLVRWASPQLHDIDALDRMVDPALK 472 ++T+KSDV+SFG+++ EL T GR P+ P + + + LD+ V+ + Sbjct: 437 RFTIKSDVWSFGILLTELTTKGRVPY----------------PGMVNREVLDQ-VERGYR 479 Query: 471 GLYPAKSLSRFADVLALCVQAEPEFRPPMSEVVQALV 361 P + D++ C + +PE RP E +QA + Sbjct: 480 MPCPPECPESLHDLMCQCWRKDPEERPTF-EYLQAFL 515
>PKN1_THETN (Q8R9T6) Probable serine/threonine-protein kinase Sps1 (EC| 2.7.11.1) Length = 625 Score = 36.6 bits (83), Expect = 0.066 Identities = 13/28 (46%), Positives = 21/28 (75%) Frame = -3 Query: 636 KSDVYSFGVVMLELLTGRKPFDSSKPRS 553 ++D+YS G+V+ E+LTG+ PF+ P S Sbjct: 190 RTDIYSLGIVLFEMLTGKVPFEGDSPIS 217
>CTR1_ARATH (Q05609) Serine/threonine-protein kinase CTR1 (EC 2.7.11.1)| Length = 821 Score = 36.6 bits (83), Expect = 0.066 Identities = 27/98 (27%), Positives = 47/98 (47%) Frame = -3 Query: 636 KSDVYSFGVVMLELLTGRKPFDSSKPRSEQSLVRWASPQLHDIDALDRMVDPALKGLYPA 457 KSDVYSFGV++ EL T ++P+ + P + V + +L + R ++P Sbjct: 731 KSDVYSFGVILWELATLQQPWGNLNPAQVVAAVGFKCKRLE----IPRNLNP-------- 778 Query: 456 KSLSRFADVLALCVQAEPEFRPPMSEVVQALVRLVQRA 343 + A ++ C EP RP + ++ L L++ A Sbjct: 779 ----QVAAIIEGCWTNEPWKRPSFATIMDLLRPLIKSA 812
>MKK2_YEAST (P32491) MAP kinase kinase MKK2/SSP33 (EC 2.7.12.2)| Length = 506 Score = 36.6 bits (83), Expect = 0.066 Identities = 21/56 (37%), Positives = 31/56 (55%), Gaps = 6/56 (10%) Frame = -3 Query: 645 YTMKSDVYSFGVVMLELLTGRKPFDSSK------PRSEQSLVRWASPQLHDIDALD 496 Y++ DV+S G+ +LE+ GR PF+S K P +++ SPQL D LD Sbjct: 392 YSVTCDVWSLGLTLLEVAGGRFPFESDKITQNVAPIELLTMILTFSPQLKDEPELD 447
>SRC_AVIS2 (P15054) Tyrosine-protein kinase transforming protein Src (EC| 2.7.10.2) (p60-Src) (v-Src) (pp60v-src) Length = 586 Score = 36.6 bits (83), Expect = 0.066 Identities = 28/97 (28%), Positives = 49/97 (50%), Gaps = 1/97 (1%) Frame = -3 Query: 648 QYTMKSDVYSFGVVMLELLT-GRKPFDSSKPRSEQSLVRWASPQLHDIDALDRMVDPALK 472 ++T+KSDV+SFG+++ EL T GR P+ P + + + LD+ V+ + Sbjct: 437 RFTIKSDVWSFGILLTELTTKGRVPY----------------PGMVNREVLDQ-VERGYR 479 Query: 471 GLYPAKSLSRFADVLALCVQAEPEFRPPMSEVVQALV 361 P + D++ C + +PE RP E +QA + Sbjct: 480 MPCPPECPESLHDLMCQCWRKDPEERPTF-EYLQAFL 515
>TXK_MOUSE (P42682) Tyrosine-protein kinase TXK (EC 2.7.10.2) (PTK-RL-18)| (Resting lymphocyte kinase) Length = 527 Score = 36.6 bits (83), Expect = 0.066 Identities = 26/101 (25%), Positives = 47/101 (46%), Gaps = 1/101 (0%) Frame = -3 Query: 648 QYTMKSDVYSFGVVMLELLT-GRKPFDSSKPRSEQSLVRWASPQLHDIDALDRMVDPALK 472 +Y+ KSDV+SFGV+M E+ T G+ PF++ L ++A+ + + Sbjct: 442 KYSSKSDVWSFGVLMWEVFTEGKMPFENKS-------------NLQVVEAISQ----GFR 484 Query: 471 GLYPAKSLSRFADVLALCVQAEPEFRPPMSEVVQALVRLVQ 349 P + V+ C P+ RP +E++Q L + + Sbjct: 485 LYRPHLAPMTIYRVMYSCWHESPKGRPTFAELLQVLTEIAE 525
>PKNB_LACLA (Q9CEF5) Probable serine/threonine-protein kinase pknB (EC| 2.7.11.1) Length = 627 Score = 36.6 bits (83), Expect = 0.066 Identities = 13/24 (54%), Positives = 21/24 (87%) Frame = -3 Query: 642 TMKSDVYSFGVVMLELLTGRKPFD 571 T++SD+Y+ G+++ ELLTG+ PFD Sbjct: 190 TVQSDIYAIGIILFELLTGQIPFD 213
>ARAF_RAT (P14056) A-Raf proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) Length = 604 Score = 36.2 bits (82), Expect = 0.087 Identities = 26/101 (25%), Positives = 48/101 (47%) Frame = -3 Query: 645 YTMKSDVYSFGVVMLELLTGRKPFDSSKPRSEQSLVRWASPQLHDIDALDRMVDPALKGL 466 Y+ +SDVY++GVV+ EL+TG P+ R + + D+ + A++ L Sbjct: 484 YSFQSDVYAYGVVLYELMTGSLPYSHIGSRDQIIFMVGRGYLSPDLSKIFSNCPKAMRRL 543 Query: 465 YPAKSLSRFADVLALCVQAEPEFRPPMSEVVQALVRLVQRA 343 L C++ + E RP +++ A + L+QR+ Sbjct: 544 ------------LTDCLKFQREERPLFPQIL-ATIELLQRS 571
>ARAF_MOUSE (P04627) A-Raf proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) Length = 604 Score = 36.2 bits (82), Expect = 0.087 Identities = 26/101 (25%), Positives = 48/101 (47%) Frame = -3 Query: 645 YTMKSDVYSFGVVMLELLTGRKPFDSSKPRSEQSLVRWASPQLHDIDALDRMVDPALKGL 466 Y+ +SDVY++GVV+ EL+TG P+ R + + D+ + A++ L Sbjct: 484 YSFQSDVYAYGVVLYELMTGSLPYSHIGSRDQIIFMVGRGYLSPDLSKIFSNCPKAMRRL 543 Query: 465 YPAKSLSRFADVLALCVQAEPEFRPPMSEVVQALVRLVQRA 343 L C++ + E RP +++ A + L+QR+ Sbjct: 544 ------------LTDCLKFQREERPLFPQIL-ATIELLQRS 571
>FGFR1_DROME (Q07407) Fibroblast growth factor receptor homolog 1 precursor (EC| 2.7.10.1) (Protein heartless) Length = 729 Score = 36.2 bits (82), Expect = 0.087 Identities = 24/100 (24%), Positives = 47/100 (47%), Gaps = 1/100 (1%) Frame = -3 Query: 645 YTMKSDVYSFGVVMLELLT-GRKPFDSSKPRSEQSLVRWASPQLHDIDALDRMVDPALKG 469 Y KSDV+S+G+++ E++T G++P+ P + + L + + Sbjct: 610 YDSKSDVWSYGILLWEIMTYGQQPY----------------PTIMSAEELYTYLMSGQRM 653 Query: 468 LYPAKSLSRFADVLALCVQAEPEFRPPMSEVVQALVRLVQ 349 PAK ++ C + RPP +E+V+ + +L+Q Sbjct: 654 EKPAKCSMNIYILMRQCWHFNADDRPPFTEIVEYMDKLLQ 693
>NEK9_HUMAN (Q8TD19) Serine/threonine-protein kinase Nek9 (EC 2.7.11.1)| (NimA-related protein kinase 9) (Never in mitosis A-related kinase 9) (Nercc1 kinase) (NIMA-related kinase 8) (Nek8) Length = 979 Score = 36.2 bits (82), Expect = 0.087 Identities = 27/108 (25%), Positives = 51/108 (47%) Frame = -3 Query: 648 QYTMKSDVYSFGVVMLELLTGRKPFDSSKPRSEQSLVRWASPQLHDIDALDRMVDPALKG 469 +Y KSD+++ G V+ ELLT ++ FD++ P + + I A++ VD + Sbjct: 227 KYNFKSDIWAVGCVIFELLTLKRTFDATNP------LNLCVKIVQGIRAME--VDSSQYS 278 Query: 468 LYPAKSLSRFADVLALCVQAEPEFRPPMSEVVQALVRLVQRANMTKKM 325 L ++ C+ +PE RP E++ + +R M +K+ Sbjct: 279 L-------ELIQMVHSCLDQDPEQRPTADELLDRPLLRKRRREMEEKV 319
>M3K7_DROME (Q9V3Q6) Mitogen-activated protein kinase kinase kinase 7 (EC| 2.7.11.25) (TGF-beta-activated kinase 1) (dTAK1) Length = 678 Score = 36.2 bits (82), Expect = 0.087 Identities = 27/110 (24%), Positives = 49/110 (44%) Frame = -3 Query: 648 QYTMKSDVYSFGVVMLELLTGRKPFDSSKPRSEQSLVRWASPQLHDIDALDRMVDPALKG 469 +YT K D++S+ +V+ E+L+ ++PF K ++W + + P L Sbjct: 189 KYTEKCDIFSWAIVLWEVLSRKQPF---KGIDNAYTIQW---------KIYKGERPPLLT 236 Query: 468 LYPAKSLSRFADVLALCVQAEPEFRPPMSEVVQALVRLVQRANMTKKMLD 319 P R D++ C + PE RP M +V + +V+ K L+ Sbjct: 237 TCP----KRIEDLMTACWKTVPEDRPSMQYIVGVMHEIVKDYTGADKALE 282
>NRKA_TRYBB (Q08942) Putative serine/threonine-protein kinase A (EC 2.7.11.1)| Length = 431 Score = 35.8 bits (81), Expect = 0.11 Identities = 26/96 (27%), Positives = 42/96 (43%), Gaps = 3/96 (3%) Frame = -3 Query: 648 QYTMKSDVYSFGVVMLELLTGRKPFDSSKPRSEQSLVRWASPQLHDIDALDRMVDPALKG 469 +Y K+DV+S GV++ E++ +KPF +S L ++ L G Sbjct: 200 RYNKKADVWSLGVLLYEIMGMKKPFSASN--------------------LKGLMSKVLAG 239 Query: 468 LY---PAKSLSRFADVLALCVQAEPEFRPPMSEVVQ 370 Y P S F V+ + A+P RP + E+ Q Sbjct: 240 TYAPLPDSFSSEFKRVVDGILVADPNDRPSVREIFQ 275
>SRC_RSVP (P00526) Tyrosine-protein kinase transforming protein Src (EC| 2.7.10.2) (p60-Src) (v-Src) (pp60v-src) Length = 525 Score = 35.8 bits (81), Expect = 0.11 Identities = 25/87 (28%), Positives = 44/87 (50%), Gaps = 1/87 (1%) Frame = -3 Query: 648 QYTMKSDVYSFGVVMLELLT-GRKPFDSSKPRSEQSLVRWASPQLHDIDALDRMVDPALK 472 ++T+KSDV+SFG+++ EL T GR P+ P + + + LD+ V+ + Sbjct: 437 RFTIKSDVWSFGILLTELTTKGRVPY----------------PGMVNREVLDQ-VERGYR 479 Query: 471 GLYPAKSLSRFADVLALCVQAEPEFRP 391 P + D++ C + +PE RP Sbjct: 480 MPCPPECPESLHDLMCQCWRKDPEERP 506
>MP2K3_HUMAN (P46734) Dual specificity mitogen-activated protein kinase kinase 3| (EC 2.7.12.2) (MAP kinase kinase 3) (MAPKK 3) (MAPK/ERK kinase 3) Length = 347 Score = 35.8 bits (81), Expect = 0.11 Identities = 24/92 (26%), Positives = 41/92 (44%) Frame = -3 Query: 645 YTMKSDVYSFGVVMLELLTGRKPFDSSKPRSEQSLVRWASPQLHDIDALDRMVDPALKGL 466 Y +KSDV+S G+ M+E+ R P++S W +P L ++V+ L Sbjct: 245 YNVKSDVWSLGITMIEMAILRFPYES-----------WGTP----FQQLKQVVEEPSPQL 289 Query: 465 YPAKSLSRFADVLALCVQAEPEFRPPMSEVVQ 370 + F D A C++ P R E+++ Sbjct: 290 PADRFSPEFVDFTAQCLRKNPAERMSYLELME 321
>M3KL4_HUMAN (Q5TCX8) Mitogen-activated protein kinase kinase kinase (EC| 2.7.11.25) (Mixed lineage kinase 4) Length = 1036 Score = 35.4 bits (80), Expect = 0.15 Identities = 30/120 (25%), Positives = 52/120 (43%), Gaps = 3/120 (2%) Frame = -3 Query: 645 YTMKSDVYSFGVVMLELLTGRKPFDSSKPRSEQSLVRWASPQLHDIDALDRMVDPALKGL 466 ++ SD++S+GV++ ELLTG P+ ID L A+ L Sbjct: 321 FSKGSDIWSYGVLLWELLTGEVPY-------------------RGIDGLAVAYGVAVNKL 361 Query: 465 ---YPAKSLSRFADVLALCVQAEPEFRPPMSEVVQALVRLVQRANMTKKMLDGDASRRGD 295 P+ FA ++ C Q +P RP + +++ L ++ A MT+ + S + D Sbjct: 362 TLPIPSTCPEPFAKLMKECWQQDPHIRPSFALILEQLT-AIEGAVMTEMPQESFHSMQDD 420
>PTK7_CHICK (Q91048) Tyrosine-protein kinase-like 7 precursor (Kinase-like| protein) Length = 1051 Score = 35.4 bits (80), Expect = 0.15 Identities = 28/96 (29%), Positives = 41/96 (42%), Gaps = 1/96 (1%) Frame = -3 Query: 648 QYTMKSDVYSFGVVMLELLT-GRKPFDSSKPRSEQSLVRWASPQLHDIDALDRMVDPALK 472 +++ KSDV+SFGV+M E+ T G P+ L D + L + K Sbjct: 963 EFSTKSDVWSFGVLMWEVFTQGEMPY----------------APLADDEVLAGLKSGKTK 1006 Query: 471 GLYPAKSLSRFADVLALCVQAEPEFRPPMSEVVQAL 364 P SR ++ C P+ RP SE+ AL Sbjct: 1007 LPQPEGCPSRLTKLMQRCWAPSPKDRPSFSELAAAL 1042
>MP2K4_HUMAN (P45985) Dual specificity mitogen-activated protein kinase kinase 4| (EC 2.7.12.2) (MAP kinase kinase 4) (JNK-activating kinase 1) (c-Jun N-terminal kinase kinase 1) (JNKK) (SAPK/ERK kinase 1) (SEK1) Length = 399 Score = 35.4 bits (80), Expect = 0.15 Identities = 25/94 (26%), Positives = 45/94 (47%), Gaps = 2/94 (2%) Frame = -3 Query: 645 YTMKSDVYSFGVVMLELLTGRKPFDSSKPRSEQ--SLVRWASPQLHDIDALDRMVDPALK 472 Y ++SDV+S G+ + EL TGR P+ +Q +V+ PQL + + +R P+ Sbjct: 284 YDVRSDVWSLGITLYELATGRFPYPKWNSVFDQLTQVVKGDPPQLSNSE--EREFSPS-- 339 Query: 471 GLYPAKSLSRFADVLALCVQAEPEFRPPMSEVVQ 370 F + + LC+ + RP E+++ Sbjct: 340 ----------FINFVNLCLTKDESKRPKYKELLK 363
>TOPK_BRARE (Q6DHU8) T-lymphokine-activated killer cell-originated protein| kinase homolog (EC 2.7.12.2) (PDZ-binding kinase) Length = 339 Score = 35.4 bits (80), Expect = 0.15 Identities = 23/96 (23%), Positives = 46/96 (47%), Gaps = 3/96 (3%) Frame = -3 Query: 642 TMKSDVYSFGVVMLELLTGRKP-FDSSKPRSEQSLVRWASPQLHDIDALDRMVD--PALK 472 T K+D++++G+ + E++T P + ++ + + D DA + PAL Sbjct: 227 TDKADIFAYGLTLWEMMTLSVPHLEMLDTEGDEDDDDESFEEDFDEDAYYERLGSRPALD 286 Query: 471 GLYPAKSLSRFADVLALCVQAEPEFRPPMSEVVQAL 364 + S R ++ LC + +P+ RP + +VQ L Sbjct: 287 AVTLGGSYQRMVELFCLCTEEDPQKRPSAAHIVQVL 322
>RAF1_MOUSE (Q99N57) RAF proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (Raf-1) (C-RAF) (cRaf) Length = 648 Score = 35.4 bits (80), Expect = 0.15 Identities = 26/97 (26%), Positives = 47/97 (48%), Gaps = 3/97 (3%) Frame = -3 Query: 645 YTMKSDVYSFGVVMLELLTGRKPFDSSKPRSEQSLV---RWASPQLHDIDALDRMVDPAL 475 ++ +SDVYS+G+V+ EL+ G P+ R + + +ASP D+ L + A+ Sbjct: 525 FSFQSDVYSYGIVLYELMAGELPYAHINNRDQIIFMVGRGYASP---DLSRLYKNCPKAM 581 Query: 474 KGLYPAKSLSRFADVLALCVQAEPEFRPPMSEVVQAL 364 K L +A CV+ E RP +++ ++ Sbjct: 582 KRL------------VADCVKKVKEERPLFPQILSSI 606
>MEK2_CAEEL (Q10664) Dual specificity mitogen-activated protein kinase kinase| mek-2 (EC 2.7.12.2) (MAP kinase kinase mek-2) Length = 387 Score = 35.4 bits (80), Expect = 0.15 Identities = 16/50 (32%), Positives = 29/50 (58%) Frame = -3 Query: 645 YTMKSDVYSFGVVMLELLTGRKPFDSSKPRSEQSLVRWASPQLHDIDALD 496 YT+ SD++SFG+ ++ELL GR P + ++ A ++ D+L+ Sbjct: 245 YTISSDIWSFGLSLVELLIGRYPVPAPSQAEYATMFNVAENEIELADSLE 294
>TESK2_RAT (Q924U5) Dual specificity testis-specific protein kinase 2 (EC| 2.7.12.1) (Testicular protein kinase 2) Length = 570 Score = 35.4 bits (80), Expect = 0.15 Identities = 26/100 (26%), Positives = 44/100 (44%) Frame = -3 Query: 645 YTMKSDVYSFGVVMLELLTGRKPFDSSKPRSEQSLVRWASPQLHDIDALDRMVDPALKGL 466 Y K+DV+S+G+++ E++ + PR+E + D DA MV G Sbjct: 233 YNEKADVFSYGIILCEIIARIQADPDYLPRTENFGL--------DYDAFQHMV-----GD 279 Query: 465 YPAKSLSRFADVLALCVQAEPEFRPPMSEVVQALVRLVQR 346 P S F + C +P+ RP E+ + L ++ R Sbjct: 280 CP----SDFLQLTFNCCNMDPKLRPSFEEIGKTLEEIMSR 315
>TESK2_MOUSE (Q8VCT9) Dual specificity testis-specific protein kinase 2 (EC| 2.7.12.1) (Testicular protein kinase 2) Length = 570 Score = 35.4 bits (80), Expect = 0.15 Identities = 26/100 (26%), Positives = 44/100 (44%) Frame = -3 Query: 645 YTMKSDVYSFGVVMLELLTGRKPFDSSKPRSEQSLVRWASPQLHDIDALDRMVDPALKGL 466 Y K+DV+S+G+++ E++ + PR+E + D DA MV G Sbjct: 233 YNEKADVFSYGIILCEIIARIQADPDYLPRTENFGL--------DYDAFQNMV-----GD 279 Query: 465 YPAKSLSRFADVLALCVQAEPEFRPPMSEVVQALVRLVQR 346 P S F + C +P+ RP E+ + L ++ R Sbjct: 280 CP----SDFLQLTFNCCNMDPKLRPSFEEIGKTLKEIMSR 315
>PKN2_COREF (Q8FUI4) Serine/threonine protein kinases drp72 (EC 2.7.11.1)| Length = 520 Score = 35.4 bits (80), Expect = 0.15 Identities = 19/30 (63%), Positives = 22/30 (73%), Gaps = 2/30 (6%) Frame = -3 Query: 648 QYTMKSDVYSFGVVMLELLTGRKPF--DSS 565 Q T SDVYS GVV E+L+GR+PF DSS Sbjct: 200 QVTPASDVYSLGVVGYEMLSGRRPFTGDSS 229
>MP2K4_MOUSE (P47809) Dual specificity mitogen-activated protein kinase kinase 4| (EC 2.7.12.2) (MAP kinase kinase 4) (MAPKK 4) (MAPK/ERK kinase 4) (JNK-activating kinase 1) (C-JUN N-terminal kinase kinase 1) (JNK kinase 1) (JNKK 1) (SAPK/ERK kinase 1) (SE Length = 397 Score = 35.4 bits (80), Expect = 0.15 Identities = 25/94 (26%), Positives = 45/94 (47%), Gaps = 2/94 (2%) Frame = -3 Query: 645 YTMKSDVYSFGVVMLELLTGRKPFDSSKPRSEQ--SLVRWASPQLHDIDALDRMVDPALK 472 Y ++SDV+S G+ + EL TGR P+ +Q +V+ PQL + + +R P+ Sbjct: 282 YDVRSDVWSLGITLYELATGRFPYPKWNSVFDQLTQVVKGDPPQLSNSE--EREFSPS-- 337 Query: 471 GLYPAKSLSRFADVLALCVQAEPEFRPPMSEVVQ 370 F + + LC+ + RP E+++ Sbjct: 338 ----------FINFVNLCLTKDESKRPKYKELLK 361
>KRAF1_DROME (P11346) Raf homolog serine/threonine-protein kinase dRAF-1 (EC| 2.7.11.1) (Protein pole-hole) Length = 739 Score = 35.4 bits (80), Expect = 0.15 Identities = 35/124 (28%), Positives = 52/124 (41%), Gaps = 13/124 (10%) Frame = -3 Query: 645 YTMKSDVYSFGVVMLELLTGRKPFD--SSKP-----------RSEQSLVRWASPQLHDID 505 Y+ +SDVY+FG+VM ELL P+ S+K R + S VR +PQ Sbjct: 605 YSFQSDVYAFGIVMYELLAECLPYGHISNKDQILFMVGRGLLRPDMSQVRSDAPQ----- 659 Query: 504 ALDRMVDPALKGLYPAKSLSRFADVLALCVQAEPEFRPPMSEVVQALVRLVQRANMTKKM 325 AL R+ + +K Y K F +L + M + + R N+T+ Sbjct: 660 ALKRLAEDCIK--YTPKDRPLFRPLLNMLEN--------MLRTLPKIHRSASEPNLTQSQ 709 Query: 324 LDGD 313 L D Sbjct: 710 LQND 713
>MATK_MOUSE (P41242) Megakaryocyte-associated tyrosine-protein kinase (EC| 2.7.10.2) (Tyrosine-protein kinase CTK) (Protein kinase NTK) Length = 505 Score = 35.4 bits (80), Expect = 0.15 Identities = 29/124 (23%), Positives = 56/124 (45%), Gaps = 5/124 (4%) Frame = -3 Query: 648 QYTMKSDVYSFGVVMLELLT-GRKPFDSSKPRSEQSLVRWASPQLHDIDALDRMVDPALK 472 +++ KSDV+SFGV++ E+ + GR P+ P++ + + V+ + Sbjct: 398 RFSSKSDVWSFGVLLWEVFSYGRAPY----------------PKM-SLKEVSEAVEKGYR 440 Query: 471 GLYPAKSLSRFADVLALCVQAEPEFRPPMSEVVQALVRLVQRANMTK----KMLDGDASR 304 P ++ C +AEP RPP ++V+ L R ++ ++ + +G A Sbjct: 441 MEPPDGCPGSVHTLMGSCWEAEPARRPPFRKIVEKLGRELRSVGVSAPAGGQEAEGSAPT 500 Query: 303 RGDD 292 R D Sbjct: 501 RSQD 504
>RAF_MSV36 (P00532) Serine/threonine-protein kinase transforming protein raf| (EC 2.7.11.1) Length = 323 Score = 35.4 bits (80), Expect = 0.15 Identities = 26/97 (26%), Positives = 47/97 (48%), Gaps = 3/97 (3%) Frame = -3 Query: 645 YTMKSDVYSFGVVMLELLTGRKPFDSSKPRSEQSLV---RWASPQLHDIDALDRMVDPAL 475 ++ +SDVYS+G+V+ EL+ G P+ R + + +ASP D+ L + A+ Sbjct: 200 FSFQSDVYSYGIVLYELMAGELPYAHINNRDQIIFMVGRGYASP---DLSRLYKNCPKAI 256 Query: 474 KGLYPAKSLSRFADVLALCVQAEPEFRPPMSEVVQAL 364 K L +A CV+ E RP +++ ++ Sbjct: 257 KRL------------VADCVKKVKEERPLFPQILSSI 281
>M3K2_ARATH (Q9FZ36) Mitogen-activated protein kinase kinase kinase 2 (EC| 2.7.11.25) (Arabidospsis NPK1-related protein kinase 2) Length = 651 Score = 35.4 bits (80), Expect = 0.15 Identities = 23/92 (25%), Positives = 41/92 (44%) Frame = -3 Query: 645 YTMKSDVYSFGVVMLELLTGRKPFDSSKPRSEQSLVRWASPQLHDIDALDRMVDPALKGL 466 ++ +D++S G ++E++TG+ P+ S Q +I A+ + Sbjct: 250 HSFSADIWSVGCTVIEMVTGKAPW---------------SQQYKEIAAIFHIGTTKSHPP 294 Query: 465 YPAKSLSRFADVLALCVQAEPEFRPPMSEVVQ 370 P S D L C+Q EP RP SE+++ Sbjct: 295 IPDNISSDANDFLLKCLQQEPNLRPTASELLK 326
>FYN_XIPHE (P27446) Proto-oncogene tyrosine-protein kinase FYN (EC 2.7.10.2)| (P59-FYN) Length = 536 Score = 35.0 bits (79), Expect = 0.19 Identities = 26/97 (26%), Positives = 51/97 (52%), Gaps = 1/97 (1%) Frame = -3 Query: 648 QYTMKSDVYSFGVVMLELLT-GRKPFDSSKPRSEQSLVRWASPQLHDIDALDRMVDPALK 472 ++T+KSDV+SFG+++ EL+T GR P+ P +++ + L++ V+ + Sbjct: 441 RFTIKSDVWSFGILLTELVTKGRVPY----------------PGMNNREVLEQ-VERGYR 483 Query: 471 GLYPAKSLSRFADVLALCVQAEPEFRPPMSEVVQALV 361 P + +++ C + +PE RP E +QA + Sbjct: 484 MPCPQDCPASLHELMLQCWKKDPEERPTF-EYLQAFL 519
>TNI3K_MOUSE (Q5GIG6) Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1)| (TNNI3-interacting kinase) (Cardiac ankyrin repeat kinase) Length = 833 Score = 35.0 bits (79), Expect = 0.19 Identities = 28/95 (29%), Positives = 42/95 (44%) Frame = -3 Query: 648 QYTMKSDVYSFGVVMLELLTGRKPFDSSKPRSEQSLVRWASPQLHDIDALDRMVDPALKG 469 +YT+K+DV+S+ + + ELL G PF KP + + D + P + Sbjct: 639 RYTIKADVFSYALCLWELLIGEIPFAHLKPAAAAA------------DMAYHHIRPPIGY 686 Query: 468 LYPAKSLSRFADVLALCVQAEPEFRPPMSEVVQAL 364 P + +L A PE RP SEVV+ L Sbjct: 687 SIP----KPISSLLMRGWNACPEGRPEFSEVVRKL 717
>MET_HUMAN (P08581) Hepatocyte growth factor receptor precursor (EC 2.7.10.1)| (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met) Length = 1390 Score = 35.0 bits (79), Expect = 0.19 Identities = 29/98 (29%), Positives = 43/98 (43%), Gaps = 3/98 (3%) Frame = -3 Query: 648 QYTMKSDVYSFGVVMLELLTGRKPFDSSKPRSEQSLVRWASPQLHDIDALDRMVDPALKG 469 ++T KSDV+SFGVV+ EL+T +P D++ D V L+G Sbjct: 1259 KFTTKSDVWSFGVVLWELMTR------------------GAPPYPDVNTFDITV-YLLQG 1299 Query: 468 ---LYPAKSLSRFADVLALCVQAEPEFRPPMSEVVQAL 364 L P +V+ C + E RP SE+V + Sbjct: 1300 RRLLQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRI 1337
>M3KSL_DROME (Q95UN8) Mitogen-activated protein kinase kinase kinase (EC| 2.7.11.25) (Mixed lineage kinase) (dMLK) (Protein slipper) Length = 1161 Score = 35.0 bits (79), Expect = 0.19 Identities = 25/94 (26%), Positives = 42/94 (44%) Frame = -3 Query: 645 YTMKSDVYSFGVVMLELLTGRKPFDSSKPRSEQSLVRWASPQLHDIDALDRMVDPALKGL 466 Y+ SDV+S+GV++ EL+TG P+ P S V A++ + P Sbjct: 322 YSKFSDVWSYGVLLWELITGETPYKGFDPLSVAYGV-----------AVNTLTLP----- 365 Query: 465 YPAKSLSRFADVLALCVQAEPEFRPPMSEVVQAL 364 P + ++ C Q +P RP E+++ L Sbjct: 366 IPKTCPETWGALMKSCWQTDPHKRPGFKEILKQL 399
>EPHB2_HUMAN (P29323) Ephrin type-B receptor 2 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EPH-3) (DRT) (Receptor protein-tyrosine kinase HEK5) (ERK) (NY-REN-47 antigen) Length = 1055 Score = 35.0 bits (79), Expect = 0.19 Identities = 27/111 (24%), Positives = 49/111 (44%), Gaps = 3/111 (2%) Frame = -3 Query: 648 QYTMKSDVYSFGVVMLELLT-GRKPFDSSKPRSEQSLVRWASPQLHDIDAL--DRMVDPA 478 ++T SDV+S+G+VM E+++ G +P+ W I+A+ D + P Sbjct: 802 KFTSASDVWSYGIVMWEVMSYGERPY-------------WDMTNQDVINAIEQDYRLPP- 847 Query: 477 LKGLYPAKSLSRFADVLALCVQAEPEFRPPMSEVVQALVRLVQRANMTKKM 325 P S ++ C Q + RP ++V L ++++ N K M Sbjct: 848 -----PMDCPSALHQLMLDCWQKDRNHRPKFGQIVNTLDKMIRNPNSLKAM 893
>CAD96_DROME (Q9VBW3) Tyrosine kinase receptor Cad96Ca precursor (EC 2.7.10.1)| (Cadherin 96Ca) (Tyrosine kinase receptor HD-14) Length = 773 Score = 35.0 bits (79), Expect = 0.19 Identities = 24/99 (24%), Positives = 47/99 (47%), Gaps = 1/99 (1%) Frame = -3 Query: 645 YTMKSDVYSFGVVMLELLT-GRKPFDSSKPRSEQSLVRWASPQLHDIDALDRMVDPALKG 469 +++KSD++SFG++M E++T G P+ P + D + R V + Sbjct: 664 FSVKSDIWSFGILMWEIVTLGSTPY----------------PGISAADVM-RKVRDGYRL 706 Query: 468 LYPAKSLSRFADVLALCVQAEPEFRPPMSEVVQALVRLV 352 P +++ C +P+ RP +E++Q L +L+ Sbjct: 707 EKPEHCRRELYNIMYYCWSHDPQERPLFAEIIQMLDKLL 745
>VGFR2_HUMAN (P35968) Vascular endothelial growth factor receptor 2 precursor (EC| 2.7.10.1) (VEGFR-2) (Kinase insert domain receptor) (Protein-tyrosine kinase receptor Flk-1) (CD309 antigen) Length = 1356 Score = 35.0 bits (79), Expect = 0.19 Identities = 27/100 (27%), Positives = 42/100 (42%), Gaps = 1/100 (1%) Frame = -3 Query: 645 YTMKSDVYSFGVVMLELLT-GRKPFDSSKPRSEQSLVRWASPQLHDIDALDRMVDPALKG 469 YT++SDV+SFGV++ E+ + G P+ K E R + + Sbjct: 1082 YTIQSDVWSFGVLLWEIFSLGASPYPGVKIDEE----------------FCRRLKEGTRM 1125 Query: 468 LYPAKSLSRFADVLALCVQAEPEFRPPMSEVVQALVRLVQ 349 P + + C EP RP SE+V+ L L+Q Sbjct: 1126 RAPDYTTPEMYQTMLDCWHGEPSQRPTFSELVEHLGNLLQ 1165
>NEK9_MOUSE (Q8K1R7) Serine/threonine-protein kinase Nek9 (EC 2.7.11.1)| (NimA-related protein kinase 9) (Never in mitosis A-related kinase 9) Length = 984 Score = 35.0 bits (79), Expect = 0.19 Identities = 26/108 (24%), Positives = 50/108 (46%) Frame = -3 Query: 648 QYTMKSDVYSFGVVMLELLTGRKPFDSSKPRSEQSLVRWASPQLHDIDALDRMVDPALKG 469 +Y KSD+++ G V+ ELLT ++ FD++ P + + I A++ VD + Sbjct: 227 KYNFKSDIWAVGCVIFELLTLKRTFDATNP------LNLCVKIVQGIRAME--VDSSQYS 278 Query: 468 LYPAKSLSRFADVLALCVQAEPEFRPPMSEVVQALVRLVQRANMTKKM 325 L ++ C+ +PE RP ++ + +R M +K+ Sbjct: 279 L-------ELIQLVHACLDQDPEQRPAADALLDLPLLRTRRREMEEKV 319
>KR73_ICHV1 (Q00094) Gene 73 protein kinase (EC 2.7.11.1)| Length = 962 Score = 35.0 bits (79), Expect = 0.19 Identities = 31/105 (29%), Positives = 50/105 (47%), Gaps = 16/105 (15%) Frame = -3 Query: 633 SDVYSFGVVMLELLTGRKPFDSSKPRSEQSLVRW-------ASPQL----HDIDALDRMV 487 SD++++GV M E+ TGR PF S Q + R+ A QL H + A D V Sbjct: 488 SDMWAWGVTMWEVHTGRTPFWGGTDISMQKVFRYTGGFDNRAYNQLAVARHAMAAADSAV 547 Query: 486 DPA--LKGLYPAKSLS---RFADVLALCVQAEPEFRPPMSEVVQA 367 P L+GL +S F D++ ++ P R S+++++ Sbjct: 548 KPVPDLEGLMERGKVSLSPSFTDIMKSVLRLNPNDRATASDLLKS 592
>ERBB_ALV (P00534) Tyrosine-protein kinase transforming protein erbB (EC| 2.7.10.1) Length = 634 Score = 35.0 bits (79), Expect = 0.19 Identities = 26/59 (44%), Positives = 33/59 (55%), Gaps = 6/59 (10%) Frame = -3 Query: 645 YTMKSDVYSFGVVMLELLT-GRKPFDSSKPRSEQSLV-----RWASPQLHDIDALDRMV 487 YT +SDV+S+GV + EL+T G KP+D P SE S V R P + ID MV Sbjct: 311 YTHQSDVWSYGVTVWELMTFGSKPYDGI-PASEISSVLEKGERLPQPPICTIDVYMIMV 368
>ATG1_BOTCI (Q6H9I1) Serine/threonine-protein kinase ATG1 (EC 2.7.11.1)| (Autophagy-related protein 1) (Botryotinia fuckeliana putative kinase exons 1-3) Length = 952 Score = 35.0 bits (79), Expect = 0.19 Identities = 36/130 (27%), Positives = 55/130 (42%), Gaps = 20/130 (15%) Frame = -3 Query: 648 QYTMKSDVYSFGVVMLELLTGRKPFDS-------SKPRSEQSLVRWASPQLHDIDALDRM 490 +Y ++D++S G V+ E++TGR PF + K Q +R+ S ++ D D Sbjct: 247 KYDARADLWSIGTVLYEMMTGRPPFKAINHVQLLQKIEKNQDEIRFPSRGIYSRDLKD-- 304 Query: 489 VDPALKGLYPAKSLSR--FADVLALCVQAEP-----------EFRPPMSEVVQALVRLVQ 349 ++ L K R F + A V EP E P S V Q +R Q Sbjct: 305 ---IVRRLLKKKPEDRITFPEYFAHPVVTEPIPGLVGDDRPKEKSPETSIVRQPSLRDRQ 361 Query: 348 RANMTKKMLD 319 R + T K +D Sbjct: 362 RESPTVKHID 371
>PKN1_COREF (Q8FUI5) Probable serine/threonine protein kinase CE0033 (EC| 2.7.11.1) Length = 660 Score = 35.0 bits (79), Expect = 0.19 Identities = 14/26 (53%), Positives = 19/26 (73%) Frame = -3 Query: 636 KSDVYSFGVVMLELLTGRKPFDSSKP 559 +SDVY+ G V+ EL+TGR PF+ P Sbjct: 194 RSDVYAAGCVLYELVTGRPPFEGESP 219
>KGP25_DROME (P32023) cGMP-dependent protein kinase, isozyme 2 forms cD5/T2 (EC| 2.7.11.12) (CGK) (Foraging protein) Length = 934 Score = 35.0 bits (79), Expect = 0.19 Identities = 18/50 (36%), Positives = 28/50 (56%) Frame = -3 Query: 645 YTMKSDVYSFGVVMLELLTGRKPFDSSKPRSEQSLVRWASPQLHDIDALD 496 + + +D +S GV+M ELLTG PF S P +++ L IDA++ Sbjct: 798 HDISADYWSLGVLMFELLTGTPPFTGSDPMRTYNII------LKGIDAIE 841
>ERBB_AVIER (P00535) Tyrosine-protein kinase transforming protein erbB (EC| 2.7.10.1) Length = 604 Score = 35.0 bits (79), Expect = 0.19 Identities = 26/59 (44%), Positives = 33/59 (55%), Gaps = 6/59 (10%) Frame = -3 Query: 645 YTMKSDVYSFGVVMLELLT-GRKPFDSSKPRSEQSLV-----RWASPQLHDIDALDRMV 487 YT +SDV+S+GV + EL+T G KP+D P SE S V R P + ID MV Sbjct: 311 YTHQSDVWSYGVTVWELMTFGSKPYDGI-PASEISSVLEKGERLPQPPICTIDVYMIMV 368
>SRC2_XENLA (P13116) Tyrosine-protein kinase Src-2 (EC 2.7.10.2) (p60-Src-2)| Length = 531 Score = 35.0 bits (79), Expect = 0.19 Identities = 28/97 (28%), Positives = 48/97 (49%), Gaps = 1/97 (1%) Frame = -3 Query: 648 QYTMKSDVYSFGVVMLELLT-GRKPFDSSKPRSEQSLVRWASPQLHDIDALDRMVDPALK 472 ++T+KSDV+SFG+++ EL T GR P+ P + + + LD+ V+ + Sbjct: 436 RFTIKSDVWSFGILLTELTTKGRVPY----------------PGMVNREVLDQ-VERGYR 478 Query: 471 GLYPAKSLSRFADVLALCVQAEPEFRPPMSEVVQALV 361 P D++ C + +PE RP E +QA + Sbjct: 479 MPCPPDCPESLHDLMFQCWRKDPEERPTF-EYLQAFL 514
>SRC1_XENLA (P13115) Tyrosine-protein kinase Src-1 (EC 2.7.10.2) (p60-Src-1)| Length = 531 Score = 35.0 bits (79), Expect = 0.19 Identities = 28/97 (28%), Positives = 48/97 (49%), Gaps = 1/97 (1%) Frame = -3 Query: 648 QYTMKSDVYSFGVVMLELLT-GRKPFDSSKPRSEQSLVRWASPQLHDIDALDRMVDPALK 472 ++T+KSDV+SFG+++ EL T GR P+ P + + + LD+ V+ + Sbjct: 436 RFTIKSDVWSFGILLTELTTKGRVPY----------------PGMVNREVLDQ-VERGYR 478 Query: 471 GLYPAKSLSRFADVLALCVQAEPEFRPPMSEVVQALV 361 P D++ C + +PE RP E +QA + Sbjct: 479 MPCPPDCPESLHDLMFQCWRKDPEERPTF-EYLQAFL 514
>KGP24_DROME (Q03043) cGMP-dependent protein kinase, isozyme 2 forms| cD4/T1/T3A/T3B (EC 2.7.11.12) (CGK) (Foraging protein) Length = 1088 Score = 35.0 bits (79), Expect = 0.19 Identities = 18/50 (36%), Positives = 28/50 (56%) Frame = -3 Query: 645 YTMKSDVYSFGVVMLELLTGRKPFDSSKPRSEQSLVRWASPQLHDIDALD 496 + + +D +S GV+M ELLTG PF S P +++ L IDA++ Sbjct: 952 HDISADYWSLGVLMFELLTGTPPFTGSDPMRTYNII------LKGIDAIE 995
>EPHB2_MOUSE (P54763) Ephrin type-B receptor 2 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EPH-3) (Neural kinase) (Nuk receptor tyrosine kinase) (SEK-3) Length = 994 Score = 35.0 bits (79), Expect = 0.19 Identities = 27/111 (24%), Positives = 49/111 (44%), Gaps = 3/111 (2%) Frame = -3 Query: 648 QYTMKSDVYSFGVVMLELLT-GRKPFDSSKPRSEQSLVRWASPQLHDIDAL--DRMVDPA 478 ++T SDV+S+G+VM E+++ G +P+ W I+A+ D + P Sbjct: 810 KFTSASDVWSYGIVMWEVMSYGERPY-------------WDMTNQDVINAIEQDYRLPP- 855 Query: 477 LKGLYPAKSLSRFADVLALCVQAEPEFRPPMSEVVQALVRLVQRANMTKKM 325 P S ++ C Q + RP ++V L ++++ N K M Sbjct: 856 -----PMDCPSALHQLMLDCWQKDRNHRPKFGQIVNTLDKMIRNPNSLKAM 901
>KIT_CHICK (Q08156) Mast/stem cell growth factor receptor precursor (EC| 2.7.10.1) (SCFR) (Proto-oncogene tyrosine-protein kinase Kit) (c-kit) Length = 960 Score = 35.0 bits (79), Expect = 0.19 Identities = 23/95 (24%), Positives = 41/95 (43%), Gaps = 1/95 (1%) Frame = -3 Query: 645 YTMKSDVYSFGVVMLELLT-GRKPFDSSKPRSEQSLVRWASPQLHDIDALDRMVDPALKG 469 YT +SDV+S+G+++ EL + G P+ P + +M+ + Sbjct: 831 YTFESDVWSYGILLWELFSLGSSPY----------------PGMPVDSKFYKMIKEGYRM 874 Query: 468 LYPAKSLSRFADVLALCVQAEPEFRPPMSEVVQAL 364 P S D++ C A+P RP ++VQ + Sbjct: 875 FSPECSPPEMYDIMKSCWDADPLQRPTFKQIVQLI 909
>ERBB_AVIEU (P11273) Tyrosine-protein kinase transforming protein erbB (EC| 2.7.10.1) Length = 540 Score = 35.0 bits (79), Expect = 0.19 Identities = 26/59 (44%), Positives = 33/59 (55%), Gaps = 6/59 (10%) Frame = -3 Query: 645 YTMKSDVYSFGVVMLELLT-GRKPFDSSKPRSEQSLV-----RWASPQLHDIDALDRMV 487 YT +SDV+S+GV + EL+T G KP+D P SE S V R P + ID MV Sbjct: 311 YTHQSDVWSYGVTVWELMTFGSKPYDGI-PASEISSVLEKGERLPQPPICTIDVYMIMV 368
>CEK3_CHICK (P18461) Tyrosine kinase receptor CEK3 precursor (EC 2.7.10.1)| Length = 823 Score = 34.7 bits (78), Expect = 0.25 Identities = 26/99 (26%), Positives = 45/99 (45%), Gaps = 1/99 (1%) Frame = -3 Query: 645 YTMKSDVYSFGVVMLELLT-GRKPFDSSKPRSEQSLVRWASPQLHDIDALDRMVDPALKG 469 YT +SDV+SFGV+M E+ T G P+ ++ L +++ + Sbjct: 682 YTHQSDVWSFGVLMWEIFTLGGSPYPGI-----------------PVEELFKLLKEGHRM 724 Query: 468 LYPAKSLSRFADVLALCVQAEPEFRPPMSEVVQALVRLV 352 PA + ++ C QA P RP ++V+ L R++ Sbjct: 725 DKPANCTNELYMMMRDCWQAVPSQRPTFKQLVEDLDRIL 763
>NRKB_TRYBB (Q03428) Putative serine/threonine-protein kinase B (EC 2.7.11.1)| Length = 431 Score = 34.7 bits (78), Expect = 0.25 Identities = 30/119 (25%), Positives = 50/119 (42%), Gaps = 9/119 (7%) Frame = -3 Query: 648 QYTMKSDVYSFGVVMLELLTGRKPFDSSKPRSEQSLVRWASPQLHDIDALDRMVDPALKG 469 +Y K+DV+S GV++ E++ +KPF +S L ++ L G Sbjct: 200 RYNKKADVWSLGVLLYEIMGMKKPFSASN--------------------LKGLMSKVLAG 239 Query: 468 LY---PAKSLSRFADVLALCVQAEPEFRPPMSE------VVQALVRLVQRANMTKKMLD 319 Y P S F V+ + A+P RP + E + + L VQ +++LD Sbjct: 240 TYAPLPDSFSSEFKRVVDGILVADPNDRPSVRENFQIPYINKGLKLFVQALKKNERILD 298
>ABL_MLVAB (P00521) Tyrosine-protein kinase transforming protein Abl (EC| 2.7.10.2) (V-abl) Length = 746 Score = 34.7 bits (78), Expect = 0.25 Identities = 24/118 (20%), Positives = 56/118 (47%), Gaps = 1/118 (0%) Frame = -3 Query: 648 QYTMKSDVYSFGVVMLELLT-GRKPFDSSKPRSEQSLVRWASPQLHDIDALDRMVDPALK 472 ++++KSDV++FGV++ E+ T G P+ D+ + +++ + Sbjct: 301 KFSIKSDVWAFGVLLWEIATYGMSPYPGI-----------------DLSQVYELLEKDYR 343 Query: 471 GLYPAKSLSRFADVLALCVQAEPEFRPPMSEVVQALVRLVQRANMTKKMLDGDASRRG 298 P + +++ C Q P RP +E+ QA + Q ++++ + ++ + +RG Sbjct: 344 MERPEGCPEKVYELMRACWQWNPSDRPSFAEIHQAFETMFQESSISDE-VEKELGKRG 400
>PKN1_CORGL (Q8NU98) Probable serine/threonine protein kinase pknB (EC| 2.7.11.1) Length = 646 Score = 34.7 bits (78), Expect = 0.25 Identities = 13/26 (50%), Positives = 19/26 (73%) Frame = -3 Query: 636 KSDVYSFGVVMLELLTGRKPFDSSKP 559 +SD+Y+ G VM EL+TG+ PF+ P Sbjct: 194 RSDIYATGCVMYELVTGKPPFEGESP 219
>MLTK_MOUSE (Q9ESL4) Mitogen-activated protein kinase kinase kinase MLT (EC| 2.7.11.25) (MLK-like mitogen-activated protein triple kinase) (Leucine zipper-and sterile alpha motif kinase ZAK) (Sterile alpha motif- and leucine zipper-containing kinase AZK) ( Length = 802 Score = 34.7 bits (78), Expect = 0.25 Identities = 25/98 (25%), Positives = 42/98 (42%) Frame = -3 Query: 630 DVYSFGVVMLELLTGRKPFDSSKPRSEQSLVRWASPQLHDIDALDRMVDPALKGLYPAKS 451 D YS+GVV+ E+LT PF E V W +V+ + P+ Sbjct: 188 DTYSYGVVLWEMLTREVPFKG----LEGLQVAWL------------VVEKNERLTIPSSC 231 Query: 450 LSRFADVLALCVQAEPEFRPPMSEVVQALVRLVQRANM 337 FA++L C +A+ + RP +++ L + N+ Sbjct: 232 PRSFAELLHQCWEADAKKRPSFKQIISILESMSNDTNL 269
>KRAF1_CAEEL (Q07292) Raf homolog serine/threonine-protein kinase (EC 2.7.11.1)| (Abnormal cell lineage protein 45) Length = 813 Score = 34.7 bits (78), Expect = 0.25 Identities = 14/32 (43%), Positives = 21/32 (65%) Frame = -3 Query: 645 YTMKSDVYSFGVVMLELLTGRKPFDSSKPRSE 550 YT +SDVYSFG+ M E+L+ P+ + R + Sbjct: 662 YTPQSDVYSFGICMYEILSSHLPYSNINNRDQ 693
>SEA_AVIET (P23049) Tyrosine-protein kinase transforming protein SEA (EC| 2.7.10.2) Length = 370 Score = 34.7 bits (78), Expect = 0.25 Identities = 34/102 (33%), Positives = 45/102 (44%), Gaps = 3/102 (2%) Frame = -3 Query: 648 QYTMKSDVYSFGVVMLELLTGRKPFDSSKPRSEQSLVRWASPQLHDIDALDRMVDPALKG 469 ++T KSDV+SFGV+M ELLT R ASP ++D D M L+G Sbjct: 241 KFTTKSDVWSFGVLMWELLT-----------------RGASP-YPEVDPYD-MARYLLRG 281 Query: 468 L---YPAKSLSRFADVLALCVQAEPEFRPPMSEVVQALVRLV 352 P V+ C PE RP S +V L R++ Sbjct: 282 RRLPQPQPCPDTLYGVMLSCWAPTPEERPSFSGLVCELERVL 323
>HEP_DROME (Q23977) Dual specificity mitogen-activated protein kinase kinase| hemipterous (EC 2.7.12.2) (MAPKK) Length = 1178 Score = 34.7 bits (78), Expect = 0.25 Identities = 24/108 (22%), Positives = 48/108 (44%), Gaps = 4/108 (3%) Frame = -3 Query: 648 QYTMKSDVYSFGVVMLELLTGRKPFDSSKPRSEQSLVRWASPQLHDIDALDRMVD---PA 478 +Y +++DV+S G+ ++EL T R P++ D + L +++D P Sbjct: 372 KYDIRADVWSLGITLVELATARSPYEGCNT---------------DFEVLTKVLDSEPPC 416 Query: 477 LKGLYPAKSLSRFADVLALCVQAEPEFRPPMSEVV-QALVRLVQRANM 337 L +F D + C+ + RP E++ Q +R+ + A + Sbjct: 417 LPYGEGYNFSQQFRDFVIKCLTKNHQDRPKYPELLAQPFIRIYESAKV 464
>ABL1_MOUSE (P00520) Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2)| (p150) (c-ABL) (Abelson murine leukemia viral oncogene homolog 1) Length = 1123 Score = 34.7 bits (78), Expect = 0.25 Identities = 24/118 (20%), Positives = 56/118 (47%), Gaps = 1/118 (0%) Frame = -3 Query: 648 QYTMKSDVYSFGVVMLELLT-GRKPFDSSKPRSEQSLVRWASPQLHDIDALDRMVDPALK 472 ++++KSDV++FGV++ E+ T G P+ D+ + +++ + Sbjct: 415 KFSIKSDVWAFGVLLWEIATYGMSPYPGI-----------------DLSQVYELLEKDYR 457 Query: 471 GLYPAKSLSRFADVLALCVQAEPEFRPPMSEVVQALVRLVQRANMTKKMLDGDASRRG 298 P + +++ C Q P RP +E+ QA + Q ++++ + ++ + +RG Sbjct: 458 MERPEGCPEKVYELMRACWQWNPSDRPSFAEIHQAFETMFQESSISDE-VEKELGKRG 514
>RIPK3_HUMAN (Q9Y572) Receptor-interacting serine/threonine-protein kinase 3 (EC| 2.7.11.1) (RIP-like protein kinase 3) (Receptor-interacting protein 3) (RIP-3) Length = 518 Score = 34.7 bits (78), Expect = 0.25 Identities = 27/87 (31%), Positives = 41/87 (47%), Gaps = 2/87 (2%) Frame = -3 Query: 633 SDVYSFGVVMLELLTGRKPFDSSKPRSEQSLV--RWASPQLHDIDALDRMVDPALKGLYP 460 SDVYSFG++M +L GR+ ++P V R P L ++ P L+GL Sbjct: 202 SDVYSFGILMWAVLAGREVELPTEPSLVYEAVCNRQNRPSLAELPQAGPET-PGLEGL-- 258 Query: 459 AKSLSRFADVLALCVQAEPEFRPPMSE 379 +++ LC +EP+ RP E Sbjct: 259 -------KELMQLCWSSEPKDRPSFQE 278
>EGFR_HUMAN (P00533) Epidermal growth factor receptor precursor (EC 2.7.10.1)| (Receptor tyrosine-protein kinase ErbB-1) Length = 1210 Score = 34.7 bits (78), Expect = 0.25 Identities = 25/59 (42%), Positives = 33/59 (55%), Gaps = 6/59 (10%) Frame = -3 Query: 645 YTMKSDVYSFGVVMLELLT-GRKPFDSSKPRSEQSLV-----RWASPQLHDIDALDRMV 487 YT +SDV+S+GV + EL+T G KP+D P SE S + R P + ID MV Sbjct: 891 YTHQSDVWSYGVTVWELMTFGSKPYDGI-PASEISSILEKGERLPQPPICTIDVYMIMV 948 Score = 30.8 bits (68), Expect = 3.6 Identities = 20/56 (35%), Positives = 27/56 (48%), Gaps = 2/56 (3%) Frame = +3 Query: 489 PSCPTHRCRGAGETPTAQVTALT*AWSCRMVCVQSKALA*QPQSCRHR--SS*CTG 650 PSCP C GAGE ++T + A C C + K+ P C H ++ CTG Sbjct: 192 PSCPNGSCWGAGEENCQKLTKIICAQQCSGRC-RGKS----PSDCCHNQCAAGCTG 242
>PKNB_MYCTU (P0A5S4) Probable serine/threonine-protein kinase pknB (EC| 2.7.11.1) Length = 626 Score = 34.3 bits (77), Expect = 0.33 Identities = 15/28 (53%), Positives = 18/28 (64%) Frame = -3 Query: 636 KSDVYSFGVVMLELLTGRKPFDSSKPRS 553 +SDVYS G V+ E+LTG PF P S Sbjct: 196 RSDVYSLGCVLYEVLTGEPPFTGDSPVS 223
>PKNB_MYCBO (P0A5S5) Probable serine/threonine-protein kinase pknB (EC| 2.7.11.1) Length = 626 Score = 34.3 bits (77), Expect = 0.33 Identities = 15/28 (53%), Positives = 18/28 (64%) Frame = -3 Query: 636 KSDVYSFGVVMLELLTGRKPFDSSKPRS 553 +SDVYS G V+ E+LTG PF P S Sbjct: 196 RSDVYSLGCVLYEVLTGEPPFTGDSPVS 223
>EPHB3_XENLA (Q91735) Ephrin type-B receptor 3 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor TCK) Length = 974 Score = 34.3 bits (77), Expect = 0.33 Identities = 29/116 (25%), Positives = 51/116 (43%), Gaps = 3/116 (2%) Frame = -3 Query: 648 QYTMKSDVYSFGVVMLELLT-GRKPFDSSKPRSEQSLVRWASPQLHDIDAL--DRMVDPA 478 ++T SDV+S+G+VM E+++ G +P+ W I+A+ D + P Sbjct: 790 KFTSASDVWSYGIVMWEVMSYGERPY-------------WDMSNQDVINAIEQDYRLPP- 835 Query: 477 LKGLYPAKSLSRFADVLALCVQAEPEFRPPMSEVVQALVRLVQRANMTKKMLDGDA 310 P S ++ C + RP S++V +L +L++ A K G A Sbjct: 836 -----PMDCPSALHQLMLDCWLRDRNLRPKFSQIVSSLDKLIRNAASLKVTSPGQA 886
>PKNS_MYCGE (P47355) Putative serine/threonine-protein kinase (EC 2.7.11.1)| Length = 387 Score = 34.3 bits (77), Expect = 0.33 Identities = 14/35 (40%), Positives = 23/35 (65%), Gaps = 1/35 (2%) Frame = -3 Query: 630 DVYSFGVVMLELLTGRKPFDSS-KPRSEQSLVRWA 529 D+YS G+++ E+L GR PF+ S P E+ ++ A Sbjct: 238 DIYSLGIILFEMLVGRVPFNKSINPNKERETIQKA 272
>MET_RAT (P97523) Hepatocyte growth factor receptor precursor (EC 2.7.10.1)| (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met) Length = 1382 Score = 34.3 bits (77), Expect = 0.33 Identities = 26/96 (27%), Positives = 44/96 (45%), Gaps = 1/96 (1%) Frame = -3 Query: 648 QYTMKSDVYSFGVVMLELLT-GRKPFDSSKPRSEQSLVRWASPQLHDIDALDRMVDPALK 472 ++T KSDV+SFGV++ EL+T G P+ P ++ D ++ + Sbjct: 1260 KFTTKSDVWSFGVLLWELMTRGAPPY----------------PDVNTFDITIYLLQ-GRR 1302 Query: 471 GLYPAKSLSRFADVLALCVQAEPEFRPPMSEVVQAL 364 L P +V+ C + E RP +SE+V + Sbjct: 1303 LLQPEYCPDALYEVMLKCWHPKAEMRPSVSELVSRI 1338
>VGFR3_HUMAN (P35916) Vascular endothelial growth factor receptor 3 precursor (EC| 2.7.10.1) (VEGFR-3) (Tyrosine-protein kinase receptor FLT4) Length = 1298 Score = 34.3 bits (77), Expect = 0.33 Identities = 28/105 (26%), Positives = 48/105 (45%), Gaps = 6/105 (5%) Frame = -3 Query: 645 YTMKSDVYSFGVVMLELLT-GRKPFDSSKPRSE-----QSLVRWASPQLHDIDALDRMVD 484 YT +SDV+SFGV++ E+ + G P+ + E + R +P+L Sbjct: 1091 YTTQSDVWSFGVLLWEIFSLGASPYPGVQINEEFCQRLRDGTRMRAPEL---------AT 1141 Query: 483 PALKGLYPAKSLSRFADVLALCVQAEPEFRPPMSEVVQALVRLVQ 349 PA++ ++ C +P+ RP SE+V+ L L+Q Sbjct: 1142 PAIR------------RIMLNCWSGDPKARPAFSELVEILGDLLQ 1174
>VGFR2_COTJA (P52583) Vascular endothelial growth factor receptor 2 precursor (EC| 2.7.10.1) (VEGFR-2) (Endothelial kinase receptor EK1) (Quek 1) (Quek1) Length = 1348 Score = 34.3 bits (77), Expect = 0.33 Identities = 26/100 (26%), Positives = 43/100 (43%), Gaps = 1/100 (1%) Frame = -3 Query: 645 YTMKSDVYSFGVVMLELLT-GRKPFDSSKPRSEQSLVRWASPQLHDIDALDRMVDPALKG 469 YT++SDV+SFGV++ E+ + G P+ K E R + + Sbjct: 1075 YTIQSDVWSFGVLLWEIFSLGASPYPGVKIDEE----------------FCRRLKEGTRM 1118 Query: 468 LYPAKSLSRFADVLALCVQAEPEFRPPMSEVVQALVRLVQ 349 P + + C +P+ RP SE+V+ L L+Q Sbjct: 1119 RAPDYTTPEMYQTMLDCWHGDPKQRPTFSELVEHLGNLLQ 1158
>MP2K3_MOUSE (O09110) Dual specificity mitogen-activated protein kinase kinase 3| (EC 2.7.12.2) (MAP kinase kinase 3) (MAPKK 3) (MAPK/ERK kinase 3) Length = 347 Score = 34.3 bits (77), Expect = 0.33 Identities = 23/92 (25%), Positives = 41/92 (44%) Frame = -3 Query: 645 YTMKSDVYSFGVVMLELLTGRKPFDSSKPRSEQSLVRWASPQLHDIDALDRMVDPALKGL 466 Y +KSDV+S G+ M+E+ R P++S W +P L ++V+ L Sbjct: 245 YNVKSDVWSLGITMIEMAILRFPYES-----------WGTP----FQQLKQVVEEPSPQL 289 Query: 465 YPAKSLSRFADVLALCVQAEPEFRPPMSEVVQ 370 + F D + C++ P R E+++ Sbjct: 290 PADQFSPEFVDFTSQCLRKNPAERMSYLELME 321
>VGFR3_MOUSE (P35917) Vascular endothelial growth factor receptor 3 precursor (EC| 2.7.10.1) (VEGFR-3) (Tyrosine-protein kinase receptor FLT4) Length = 1363 Score = 34.3 bits (77), Expect = 0.33 Identities = 29/128 (22%), Positives = 55/128 (42%), Gaps = 6/128 (4%) Frame = -3 Query: 645 YTMKSDVYSFGVVMLELLT-GRKPFDSSKPRSE-----QSLVRWASPQLHDIDALDRMVD 484 YT +SDV+SFGV++ E+ + G P+ + E + R +P+L Sbjct: 1091 YTTQSDVWSFGVLLWEIFSLGASPYPGVQINEEFCQRLKDGTRMRAPEL---------AT 1141 Query: 483 PALKGLYPAKSLSRFADVLALCVQAEPEFRPPMSEVVQALVRLVQRANMTKKMLDGDASR 304 PA++ ++ C +P+ RP S++V+ L L+Q ++ + A Sbjct: 1142 PAIR------------HIMQSCWSGDPKARPAFSDLVEILGDLLQGGGWQEEEEERMALH 1189 Query: 303 RGDDQDQD 280 ++D Sbjct: 1190 SSQSSEED 1197
>SPK1_DUGTI (P42687) Tyrosine-protein kinase SPK-1 (EC 2.7.10.2)| Length = 497 Score = 34.3 bits (77), Expect = 0.33 Identities = 28/94 (29%), Positives = 41/94 (43%), Gaps = 9/94 (9%) Frame = -3 Query: 645 YTMKSDVYSFGVVMLELLTGRKPFDSSKPRSEQSLVRWASPQLHDIDALDRMVDPALKGL 466 +T KSDV+S+G+VM E+LT WAS DI A + +++ KG Sbjct: 396 FTSKSDVWSYGIVMFEILT------------------WASSPYPDIPAKE-VIEKVSKGY 436 Query: 465 ---YPAKSLS------RFADVLALCVQAEPEFRP 391 P K ++ ++ C A PE RP Sbjct: 437 RMPNPEKFITGVCCPDEIYKIMIWCWDANPEKRP 470
>KS6A2_MOUSE (Q9WUT3) Ribosomal protein S6 kinase alpha-2 (EC 2.7.11.1)| (S6K-alpha 2) (90 kDa ribosomal protein S6 kinase 2) (p90-RSK 2) (Ribosomal S6 kinase 3) (RSK-3) (pp90RSK3) (Protein-tyrosine kinase Mpk-9) (MAP kinase-activated protein kinase 1c) (M Length = 733 Score = 34.3 bits (77), Expect = 0.33 Identities = 14/36 (38%), Positives = 22/36 (61%) Frame = -3 Query: 645 YTMKSDVYSFGVVMLELLTGRKPFDSSKPRSEQSLV 538 +T +D +SFGV+M E+LTG PF + +L+ Sbjct: 236 HTQSADWWSFGVLMFEMLTGSLPFQGKDRKETMALI 271
>KS6A2_HUMAN (Q15349) Ribosomal protein S6 kinase alpha-2 (EC 2.7.11.1)| (S6K-alpha 2) (90 kDa ribosomal protein S6 kinase 2) (p90-RSK 2) (Ribosomal S6 kinase 3) (RSK-3) (pp90RSK3) (MAP kinase-activated protein kinase 1c) (MAPKAPK1C) Length = 733 Score = 34.3 bits (77), Expect = 0.33 Identities = 14/36 (38%), Positives = 22/36 (61%) Frame = -3 Query: 645 YTMKSDVYSFGVVMLELLTGRKPFDSSKPRSEQSLV 538 +T +D +SFGV+M E+LTG PF + +L+ Sbjct: 236 HTQSADWWSFGVLMFEMLTGSLPFQGKDRKETMALI 271
>EPHB2_COTJA (Q90344) Ephrin type-B receptor 2 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor QEK5) Length = 987 Score = 33.9 bits (76), Expect = 0.43 Identities = 26/111 (23%), Positives = 49/111 (44%), Gaps = 3/111 (2%) Frame = -3 Query: 648 QYTMKSDVYSFGVVMLELLT-GRKPFDSSKPRSEQSLVRWASPQLHDIDAL--DRMVDPA 478 ++T SDV+S+G+VM E+++ G +P+ W I+A+ D + P Sbjct: 803 KFTSASDVWSYGIVMWEVMSYGERPY-------------WDMTNQDVINAIEQDYRLPP- 848 Query: 477 LKGLYPAKSLSRFADVLALCVQAEPEFRPPMSEVVQALVRLVQRANMTKKM 325 P + ++ C Q + RP ++V L ++++ N K M Sbjct: 849 -----PMDCPNALHQLMLDCWQKDRNHRPKFGQIVNTLDKMIRNPNSLKAM 894
>GUC2D_RAT (P51839) Olfactory guanylyl cyclase GC-D precursor (EC 4.6.1.2)| (Guanylate cyclase, olfactory) Length = 1110 Score = 33.9 bits (76), Expect = 0.43 Identities = 23/90 (25%), Positives = 42/90 (46%), Gaps = 1/90 (1%) Frame = -3 Query: 642 TMKSDVYSFGVVMLELLTGRKPFDSSKPRSEQSLVRWASPQLHDIDALDRMVDPALKGLY 463 T K DV+S G+++ E+LT P+ S +E+ + + ASP P + L Sbjct: 737 TFKGDVFSLGIILQEVLTRDPPYCSWGLSAEEIIRKVASP------------PPLCRPLV 784 Query: 462 -PAKSLSRFADVLALCVQAEPEFRPPMSEV 376 P + ++ LC + P+ RP + ++ Sbjct: 785 SPDQGPLECIQLMQLCWEEAPDDRPSLDQI 814
>EPHB2_CHICK (P28693) Ephrin type-B receptor 2 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor CEK5) Length = 1004 Score = 33.9 bits (76), Expect = 0.43 Identities = 26/111 (23%), Positives = 49/111 (44%), Gaps = 3/111 (2%) Frame = -3 Query: 648 QYTMKSDVYSFGVVMLELLT-GRKPFDSSKPRSEQSLVRWASPQLHDIDAL--DRMVDPA 478 ++T SDV+S+G+VM E+++ G +P+ W I+A+ D + P Sbjct: 820 KFTSASDVWSYGIVMWEVMSYGERPY-------------WDMTNQDVINAIEQDYRLPP- 865 Query: 477 LKGLYPAKSLSRFADVLALCVQAEPEFRPPMSEVVQALVRLVQRANMTKKM 325 P + ++ C Q + RP ++V L ++++ N K M Sbjct: 866 -----PMDCPNALHQLMLDCWQKDRNHRPKFGQIVNTLDKMIRNPNSLKAM 911
>MET_PONPY (Q2IBD8) Hepatocyte growth factor receptor precursor (EC 2.7.10.1)| (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met) Length = 1390 Score = 33.9 bits (76), Expect = 0.43 Identities = 28/98 (28%), Positives = 43/98 (43%), Gaps = 3/98 (3%) Frame = -3 Query: 648 QYTMKSDVYSFGVVMLELLTGRKPFDSSKPRSEQSLVRWASPQLHDIDALDRMVDPALKG 469 ++T KSDV+SFGV++ EL+T +P D++ D V L+G Sbjct: 1259 KFTTKSDVWSFGVLLWELMTR------------------GAPPYPDVNTFDITV-YLLQG 1299 Query: 468 ---LYPAKSLSRFADVLALCVQAEPEFRPPMSEVVQAL 364 L P +V+ C + E RP SE+V + Sbjct: 1300 RRLLQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRI 1337
>MET_PANTR (Q2QLF1) Hepatocyte growth factor receptor precursor (EC 2.7.10.1)| (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met) Length = 1390 Score = 33.9 bits (76), Expect = 0.43 Identities = 28/98 (28%), Positives = 43/98 (43%), Gaps = 3/98 (3%) Frame = -3 Query: 648 QYTMKSDVYSFGVVMLELLTGRKPFDSSKPRSEQSLVRWASPQLHDIDALDRMVDPALKG 469 ++T KSDV+SFGV++ EL+T +P D++ D V L+G Sbjct: 1259 KFTTKSDVWSFGVLLWELMTR------------------GAPPYPDVNTFDITV-YLLQG 1299 Query: 468 ---LYPAKSLSRFADVLALCVQAEPEFRPPMSEVVQAL 364 L P +V+ C + E RP SE+V + Sbjct: 1300 RRLLQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRI 1337
>YES_XIPHE (P27447) Tyrosine-protein kinase Yes (EC 2.7.10.2) (p61-Yes)| Length = 543 Score = 33.9 bits (76), Expect = 0.43 Identities = 26/97 (26%), Positives = 49/97 (50%), Gaps = 1/97 (1%) Frame = -3 Query: 648 QYTMKSDVYSFGVVMLELLT-GRKPFDSSKPRSEQSLVRWASPQLHDIDALDRMVDPALK 472 ++T+KSDV+SFG+++ EL+T GR P+ P + + + L++ VD + Sbjct: 448 RFTIKSDVWSFGILLTELVTKGRVPY----------------PGMVNREVLEQ-VDRGYR 490 Query: 471 GLYPAKSLSRFADVLALCVQAEPEFRPPMSEVVQALV 361 P +++ C + EP+ RP E +Q+ + Sbjct: 491 MPCPQGCPESLHEMMRQCWKKEPDERPTF-EYIQSFL 526
>PKNB_MYCLE (P54744) Probable serine/threonine-protein kinase pknB (EC| 2.7.11.1) Length = 622 Score = 33.9 bits (76), Expect = 0.43 Identities = 15/28 (53%), Positives = 18/28 (64%) Frame = -3 Query: 636 KSDVYSFGVVMLELLTGRKPFDSSKPRS 553 +SDVYS G V+ E+LTG PF P S Sbjct: 195 RSDVYSLGCVLYEILTGEPPFIGDSPVS 222
>MLTK_HUMAN (Q9NYL2) Mitogen-activated protein kinase kinase kinase MLT (EC| 2.7.11.25) (MLK-like mitogen-activated protein triple kinase) (Leucine zipper-and sterile alpha motif-containing kinase) (Sterile alpha motif- and leucine zipper-containing kinase Length = 800 Score = 33.9 bits (76), Expect = 0.43 Identities = 25/101 (24%), Positives = 43/101 (42%) Frame = -3 Query: 630 DVYSFGVVMLELLTGRKPFDSSKPRSEQSLVRWASPQLHDIDALDRMVDPALKGLYPAKS 451 D YS+GVV+ E+LT PF E V W +V+ + P+ Sbjct: 188 DTYSYGVVLWEMLTREVPFKG----LEGLQVAWL------------VVEKNERLTIPSSC 231 Query: 450 LSRFADVLALCVQAEPEFRPPMSEVVQALVRLVQRANMTKK 328 FA++L C +A+ + RP +++ L + ++ K Sbjct: 232 PRSFAELLHQCWEADAKKRPSFKQIISILESMSNDTSLPDK 272
>INSR_MOUSE (P15208) Insulin receptor precursor (EC 2.7.10.1) (IR) [Contains:| Insulin receptor alpha subunit; Insulin receptor beta subunit] Length = 1372 Score = 33.9 bits (76), Expect = 0.43 Identities = 25/94 (26%), Positives = 41/94 (43%) Frame = -3 Query: 645 YTMKSDVYSFGVVMLELLTGRKPFDSSKPRSEQSLVRWASPQLHDIDALDRMVDPALKGL 466 +T SD++SFGVV+ E+ + +EQ ++ Q+ +DP Sbjct: 1203 FTASSDMWSFGVVLWEITS----------LAEQPYQGLSNEQVLKFVMDGGYLDP----- 1247 Query: 465 YPAKSLSRFADVLALCVQAEPEFRPPMSEVVQAL 364 P R D++ +C Q P+ RP E+V L Sbjct: 1248 -PDNCPERLTDLMRMCWQFNPKMRPTFLEIVNLL 1280
>FGR_MOUSE (P14234) Proto-oncogene tyrosine-protein kinase FGR (EC 2.7.10.2)| (P55-FGR) (C-FGR) Length = 517 Score = 33.9 bits (76), Expect = 0.43 Identities = 15/32 (46%), Positives = 24/32 (75%), Gaps = 1/32 (3%) Frame = -3 Query: 648 QYTMKSDVYSFGVVMLELLT-GRKPFDSSKPR 556 ++T+KSDV+SFG+++ EL+T GR P+ R Sbjct: 422 RFTVKSDVWSFGILLTELITKGRVPYPGMNNR 453
>ERBB3_RAT (Q62799) Receptor tyrosine-protein kinase erbB-3 precursor (EC| 2.7.10.1) (c-erbB3) Length = 1339 Score = 33.9 bits (76), Expect = 0.43 Identities = 37/137 (27%), Positives = 60/137 (43%), Gaps = 20/137 (14%) Frame = -3 Query: 648 QYTMKSDVYSFGVVMLELLT-GRKPFDSSKPRSEQSLV----RWASPQLHDIDA------ 502 +YT +SDV+S+GV + EL+T G +P+ + L+ R A PQ+ ID Sbjct: 885 KYTHQSDVWSYGVTVWELMTFGAEPYAGLRLAEIPDLLEKGERLAQPQICTIDVYMVMVK 944 Query: 501 ---LDRMVDPALKGLYPAKSLSRFA---DVLALCVQAEPEFRPPMSEVVQALVRLVQRAN 340 +D + P K L A +R A + +A PP +E + +Q A Sbjct: 945 CWMIDENIRPTFKEL--ANEFTRMARDPPRYLVIKRASGPGTPPAAEPSVLTTKELQEAE 1002 Query: 339 MTKKM---LDGDASRRG 298 + ++ LD +A G Sbjct: 1003 LEPELDLDLDLEAEEEG 1019
>FGR_HUMAN (P09769) Proto-oncogene tyrosine-protein kinase FGR (EC 2.7.10.2)| (P55-FGR) (C-FGR) Length = 529 Score = 33.9 bits (76), Expect = 0.43 Identities = 15/32 (46%), Positives = 24/32 (75%), Gaps = 1/32 (3%) Frame = -3 Query: 648 QYTMKSDVYSFGVVMLELLT-GRKPFDSSKPR 556 ++T+KSDV+SFG+++ EL+T GR P+ R Sbjct: 434 RFTIKSDVWSFGILLTELITKGRIPYPGMNKR 465
>MET_OTOGA (Q2QLH6) Hepatocyte growth factor receptor precursor (EC 2.7.10.1)| (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met) Length = 1382 Score = 33.9 bits (76), Expect = 0.43 Identities = 28/98 (28%), Positives = 43/98 (43%), Gaps = 3/98 (3%) Frame = -3 Query: 648 QYTMKSDVYSFGVVMLELLTGRKPFDSSKPRSEQSLVRWASPQLHDIDALDRMVDPALKG 469 ++T KSDV+SFGV++ EL+T +P D++ D V L+G Sbjct: 1260 KFTTKSDVWSFGVLLWELMTR------------------GAPPYPDVNTFDITV-YLLQG 1300 Query: 468 ---LYPAKSLSRFADVLALCVQAEPEFRPPMSEVVQAL 364 L P +V+ C + E RP SE+V + Sbjct: 1301 RRLLQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRI 1338
>MET_MICMU (Q2QL89) Hepatocyte growth factor receptor precursor (EC 2.7.10.1)| (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met) Length = 1382 Score = 33.9 bits (76), Expect = 0.43 Identities = 28/98 (28%), Positives = 43/98 (43%), Gaps = 3/98 (3%) Frame = -3 Query: 648 QYTMKSDVYSFGVVMLELLTGRKPFDSSKPRSEQSLVRWASPQLHDIDALDRMVDPALKG 469 ++T KSDV+SFGV++ EL+T +P D++ D V L+G Sbjct: 1260 KFTTKSDVWSFGVLLWELMTR------------------GAPPYPDVNTFDITV-YLLQG 1300 Query: 468 ---LYPAKSLSRFADVLALCVQAEPEFRPPMSEVVQAL 364 L P +V+ C + E RP SE+V + Sbjct: 1301 RRLLQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRI 1338
>M3K9_HUMAN (P80192) Mitogen-activated protein kinase kinase kinase 9 (EC| 2.7.11.25) (Mixed lineage kinase 1) Length = 1104 Score = 33.9 bits (76), Expect = 0.43 Identities = 26/100 (26%), Positives = 41/100 (41%), Gaps = 3/100 (3%) Frame = -3 Query: 645 YTMKSDVYSFGVVMLELLTGRKPFDSSKPRSEQSLVRWASPQLHDIDALDRMVDPALKGL 466 ++ SDV+S+GV++ ELLTG PF ID L A+ L Sbjct: 326 FSKGSDVWSYGVLLWELLTGEVPF-------------------RGIDGLAVAYGVAMNKL 366 Query: 465 ---YPAKSLSRFADVLALCVQAEPEFRPPMSEVVQALVRL 355 P+ FA ++ C +P RP + ++ L + Sbjct: 367 ALPIPSTCPEPFAKLMEDCWNPDPHSRPSFTNILDQLTTI 406
>RIPK1_HUMAN (Q13546) Receptor-interacting serine/threonine-protein kinase 1 (EC| 2.7.11.1) (Serine/threonine-protein kinase RIP) (Cell death protein RIP) (Receptor-interacting protein) Length = 671 Score = 33.9 bits (76), Expect = 0.43 Identities = 26/85 (30%), Positives = 42/85 (49%), Gaps = 1/85 (1%) Frame = -3 Query: 642 TMKSDVYSFGVVMLELLTGRKPFDSSKPRSEQSLVRW-ASPQLHDIDALDRMVDPALKGL 466 T KSDVYSF VV+ + ++P++++ EQ L+ S D+D + Sbjct: 206 TEKSDVYSFAVVLWAIFANKEPYENA--ICEQQLIMCIKSGNRPDVDDITEYC------- 256 Query: 465 YPAKSLSRFADVLALCVQAEPEFRP 391 P + +S ++ LC +A PE RP Sbjct: 257 -PREIIS----LMKLCWEANPEARP 276
>MET_MOUSE (P16056) Hepatocyte growth factor receptor precursor (EC 2.7.10.1)| (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met) Length = 1379 Score = 33.9 bits (76), Expect = 0.43 Identities = 26/96 (27%), Positives = 43/96 (44%), Gaps = 1/96 (1%) Frame = -3 Query: 648 QYTMKSDVYSFGVVMLELLT-GRKPFDSSKPRSEQSLVRWASPQLHDIDALDRMVDPALK 472 ++T KSDV+SFGV++ EL+T G P+ P ++ D ++ + Sbjct: 1257 KFTTKSDVWSFGVLLWELMTRGAPPY----------------PDVNTFDITIYLLQ-GRR 1299 Query: 471 GLYPAKSLSRFADVLALCVQAEPEFRPPMSEVVQAL 364 L P +V+ C + E RP SE+V + Sbjct: 1300 LLQPEYCPDALYEVMLKCWHPKAEMRPSFSELVSRI 1335
>M3K1_MOUSE (P53349) Mitogen-activated protein kinase kinase kinase 1 (EC| 2.7.11.25) (MAPK/ERK kinase kinase 1) (MEK kinase 1) (MEKK 1) Length = 1493 Score = 33.9 bits (76), Expect = 0.43 Identities = 20/93 (21%), Positives = 43/93 (46%) Frame = -3 Query: 648 QYTMKSDVYSFGVVMLELLTGRKPFDSSKPRSEQSLVRWASPQLHDIDALDRMVDPALKG 469 QY DV+S G ++E+ + P+++ K + +L+ + ++ + P L+ Sbjct: 1406 QYGRSCDVWSVGCAIIEMACAKPPWNAEKHSNHLALI-FKIASATTAPSIPSHLSPGLR- 1463 Query: 468 LYPAKSLSRFADVLALCVQAEPEFRPPMSEVVQ 370 DV C++ +P+ RPP E+++ Sbjct: 1464 -----------DVAVRCLELQPQDRPPSRELLK 1485
>ABL1_HUMAN (P00519) Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2)| (p150) (c-ABL) (Abelson murine leukemia viral oncogene homolog 1) Length = 1130 Score = 33.9 bits (76), Expect = 0.43 Identities = 22/109 (20%), Positives = 51/109 (46%), Gaps = 1/109 (0%) Frame = -3 Query: 648 QYTMKSDVYSFGVVMLELLT-GRKPFDSSKPRSEQSLVRWASPQLHDIDALDRMVDPALK 472 ++++KSDV++FGV++ E+ T G P+ D+ + +++ + Sbjct: 415 KFSIKSDVWAFGVLLWEIATYGMSPYPGI-----------------DLSQVYELLEKDYR 457 Query: 471 GLYPAKSLSRFADVLALCVQAEPEFRPPMSEVVQALVRLVQRANMTKKM 325 P + +++ C Q P RP +E+ QA + Q ++++ ++ Sbjct: 458 MERPEGCPEKVYELMRACWQWNPSDRPSFAEIHQAFETMFQESSISDEV 506
>VGFR3_RAT (Q91ZT1) Vascular endothelial growth factor receptor 3 precursor (EC| 2.7.10.1) (VEGFR-3) (Tyrosine-protein kinase receptor FLT4) Length = 1363 Score = 33.9 bits (76), Expect = 0.43 Identities = 27/105 (25%), Positives = 48/105 (45%), Gaps = 6/105 (5%) Frame = -3 Query: 645 YTMKSDVYSFGVVMLELLT-GRKPFDSSKPRSE-----QSLVRWASPQLHDIDALDRMVD 484 YT +SDV+SFGV++ E+ + G P+ + E + R +P+L Sbjct: 1091 YTTQSDVWSFGVLLWEIFSLGASPYPGVQINEEFCQRLKDGTRMRAPEL---------AT 1141 Query: 483 PALKGLYPAKSLSRFADVLALCVQAEPEFRPPMSEVVQALVRLVQ 349 PA++ ++ C +P+ RP S++V+ L L+Q Sbjct: 1142 PAIR------------HIMQSCWSGDPKARPAFSDLVEILGDLLQ 1174
>MET_HORSE (Q2QLA9) Hepatocyte growth factor receptor precursor (EC 2.7.10.1)| (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met) Length = 1381 Score = 33.9 bits (76), Expect = 0.43 Identities = 28/98 (28%), Positives = 43/98 (43%), Gaps = 3/98 (3%) Frame = -3 Query: 648 QYTMKSDVYSFGVVMLELLTGRKPFDSSKPRSEQSLVRWASPQLHDIDALDRMVDPALKG 469 ++T KSDV+SFGV++ EL+T +P D++ D V L+G Sbjct: 1259 KFTTKSDVWSFGVLLWELMTR------------------GAPPYPDVNTFDITV-YLLQG 1299 Query: 468 ---LYPAKSLSRFADVLALCVQAEPEFRPPMSEVVQAL 364 L P +V+ C + E RP SE+V + Sbjct: 1300 RRLLQPEYCPDPLYEVMLKCWHPKAELRPSFSELVSRI 1337
>MET_CALMO (Q2QLC0) Hepatocyte growth factor receptor precursor (EC 2.7.10.1)| (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met) Length = 1381 Score = 33.9 bits (76), Expect = 0.43 Identities = 28/98 (28%), Positives = 43/98 (43%), Gaps = 3/98 (3%) Frame = -3 Query: 648 QYTMKSDVYSFGVVMLELLTGRKPFDSSKPRSEQSLVRWASPQLHDIDALDRMVDPALKG 469 ++T KSDV+SFGV++ EL+T +P D++ D V L+G Sbjct: 1259 KFTTKSDVWSFGVLLWELMTR------------------GAPPYPDVNTFDITV-YLLQG 1299 Query: 468 ---LYPAKSLSRFADVLALCVQAEPEFRPPMSEVVQAL 364 L P +V+ C + E RP SE+V + Sbjct: 1300 RRLLQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRI 1337
>MET_CALJA (Q2QLG5) Hepatocyte growth factor receptor precursor (EC 2.7.10.1)| (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met) Length = 1381 Score = 33.9 bits (76), Expect = 0.43 Identities = 28/98 (28%), Positives = 43/98 (43%), Gaps = 3/98 (3%) Frame = -3 Query: 648 QYTMKSDVYSFGVVMLELLTGRKPFDSSKPRSEQSLVRWASPQLHDIDALDRMVDPALKG 469 ++T KSDV+SFGV++ EL+T +P D++ D V L+G Sbjct: 1259 KFTTKSDVWSFGVLLWELMTR------------------GAPPYPDVNTFDITV-YLLQG 1299 Query: 468 ---LYPAKSLSRFADVLALCVQAEPEFRPPMSEVVQAL 364 L P +V+ C + E RP SE+V + Sbjct: 1300 RRLLQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRI 1337
>LCK_SAISC (Q95KR7) Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2)| (p56-LCK) (Lymphocyte cell-specific protein-tyrosine kinase) Length = 508 Score = 33.9 bits (76), Expect = 0.43 Identities = 18/39 (46%), Positives = 28/39 (71%), Gaps = 2/39 (5%) Frame = -3 Query: 645 YTMKSDVYSFGVVMLELLT-GRKPFDS-SKPRSEQSLVR 535 +T+KSDV+SFG++M E++T GR P+ + P Q+L R Sbjct: 416 FTIKSDVWSFGILMTEIVTHGRIPYPGMTNPEVIQNLER 454
>INSR_RAT (P15127) Insulin receptor precursor (EC 2.7.10.1) (IR) [Contains:| Insulin receptor alpha subunit; Insulin receptor beta subunit] Length = 1383 Score = 33.9 bits (76), Expect = 0.43 Identities = 25/94 (26%), Positives = 41/94 (43%) Frame = -3 Query: 645 YTMKSDVYSFGVVMLELLTGRKPFDSSKPRSEQSLVRWASPQLHDIDALDRMVDPALKGL 466 +T SD++SFGVV+ E+ + +EQ ++ Q+ +DP Sbjct: 1214 FTASSDMWSFGVVLWEITS----------LAEQPYQGLSNEQVLKFVMDGGYLDP----- 1258 Query: 465 YPAKSLSRFADVLALCVQAEPEFRPPMSEVVQAL 364 P R D++ +C Q P+ RP E+V L Sbjct: 1259 -PDNCPERLTDLMRMCWQFNPKMRPTFLEIVNLL 1291
>YES_AVISY (P00527) Tyrosine-protein kinase transforming protein YES (EC| 2.7.10.2) (Fragment) Length = 528 Score = 33.5 bits (75), Expect = 0.56 Identities = 25/97 (25%), Positives = 50/97 (51%), Gaps = 1/97 (1%) Frame = -3 Query: 648 QYTMKSDVYSFGVVMLELLT-GRKPFDSSKPRSEQSLVRWASPQLHDIDALDRMVDPALK 472 ++T+KSDV+SFG+++ EL+T GR P+ P + + + L++ V+ + Sbjct: 438 RFTIKSDVWSFGILLTELVTKGRVPY----------------PGMVNREVLEQ-VERGYR 480 Query: 471 GLYPAKSLSRFADVLALCVQAEPEFRPPMSEVVQALV 361 P +++ LC + +P+ RP E +Q+ + Sbjct: 481 MPCPQGCPESLHELMKLCWKKDPDERPTF-EYIQSFL 516
>FYN_XENLA (P13406) Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2)| (p59-Fyn) Length = 536 Score = 33.5 bits (75), Expect = 0.56 Identities = 15/32 (46%), Positives = 24/32 (75%), Gaps = 1/32 (3%) Frame = -3 Query: 648 QYTMKSDVYSFGVVMLELLT-GRKPFDSSKPR 556 ++T+KSDV+SFG+++ EL+T GR P+ R Sbjct: 441 RFTIKSDVWSFGILLTELVTKGRVPYPGMNNR 472
>FYN_HUMAN (P06241) Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2)| (p59-Fyn) (Protooncogene Syn) (SLK) Length = 536 Score = 33.5 bits (75), Expect = 0.56 Identities = 15/32 (46%), Positives = 24/32 (75%), Gaps = 1/32 (3%) Frame = -3 Query: 648 QYTMKSDVYSFGVVMLELLT-GRKPFDSSKPR 556 ++T+KSDV+SFG+++ EL+T GR P+ R Sbjct: 441 RFTIKSDVWSFGILLTELVTKGRVPYPGMNNR 472
>TESK1_RAT (Q63572) Dual specificity testis-specific protein kinase 1 (EC| 2.7.12.1) (Testicular protein kinase 1) Length = 628 Score = 33.5 bits (75), Expect = 0.56 Identities = 28/101 (27%), Positives = 45/101 (44%), Gaps = 1/101 (0%) Frame = -3 Query: 645 YTMKSDVYSFGVVMLELLTGRKPFDSS-KPRSEQSLVRWASPQLHDIDALDRMVDPALKG 469 Y K+DV++FG+V+ EL+ R P D PR+E +D PA + Sbjct: 229 YDEKADVFAFGIVLCELI-ARVPADPDYLPRTED----------FGLDV------PAFRT 271 Query: 468 LYPAKSLSRFADVLALCVQAEPEFRPPMSEVVQALVRLVQR 346 L F + C EP R P +E+ Q L +++++ Sbjct: 272 LVGNDCPLPFLLLAIHCCSMEPSARAPFTEITQHLEQILEQ 312
>JAK2_RAT (Q62689) Tyrosine-protein kinase JAK2 (EC 2.7.10.2) (Janus kinase 2)| (JAK-2) Length = 1132 Score = 33.5 bits (75), Expect = 0.56 Identities = 31/136 (22%), Positives = 55/136 (40%), Gaps = 7/136 (5%) Frame = -3 Query: 642 TMKSDVYSFGVVMLELLTGRKPFDSSKPRSEQSLVRWASPQLHDIDALDRMVDPALKGLY 463 T+ +D +SFG + E+ +G KP S +D+ ++ K Sbjct: 731 TLATDKWSFGTTLWEICSG-----GDKPLSA-------------LDSQRKLQFYEDKHQL 772 Query: 462 PAKSLSRFADVLALCVQAEPEFRPPMSEVVQAL-------VRLVQRANMTKKMLDGDASR 304 PA + A+++ C+ EP+FRP V++ L L+ +M M G Sbjct: 773 PAPKWTELANLINTCMDYEPDFRPAFRAVIRDLNSLFTPDYELLTENDMLPNMRIGALGF 832 Query: 303 RGDDQDQDFI*WKHNH 256 G +D+D ++ H Sbjct: 833 SGAFEDRDPTQFEERH 848
>VGFR2_MOUSE (P35918) Vascular endothelial growth factor receptor 2 precursor (EC| 2.7.10.1) (VEGFR-2) (Protein-tyrosine kinase receptor flk-1) (Fetal liver kinase 1) (Kinase NYK) Length = 1367 Score = 33.5 bits (75), Expect = 0.56 Identities = 26/100 (26%), Positives = 42/100 (42%), Gaps = 1/100 (1%) Frame = -3 Query: 645 YTMKSDVYSFGVVMLELLT-GRKPFDSSKPRSEQSLVRWASPQLHDIDALDRMVDPALKG 469 YT++SDV+SFGV++ E+ + G P+ K E R + + Sbjct: 1080 YTIQSDVWSFGVLLWEIFSLGASPYPGVKIDEE----------------FCRRLKEGTRM 1123 Query: 468 LYPAKSLSRFADVLALCVQAEPEFRPPMSEVVQALVRLVQ 349 P + + C +P RP SE+V+ L L+Q Sbjct: 1124 RAPDYTTPEMYQTMLDCWHEDPNQRPSFSELVEHLGNLLQ 1163
>HCK_HUMAN (P08631) Tyrosine-protein kinase HCK (EC 2.7.10.2)| (p59-HCK/p60-HCK) (Hemopoietic cell kinase) Length = 525 Score = 33.5 bits (75), Expect = 0.56 Identities = 17/39 (43%), Positives = 29/39 (74%), Gaps = 2/39 (5%) Frame = -3 Query: 645 YTMKSDVYSFGVVMLELLT-GRKPFDS-SKPRSEQSLVR 535 +T+KSDV+SFG++++E++T GR P+ S P ++L R Sbjct: 433 FTIKSDVWSFGILLMEIVTYGRIPYPGMSNPEVIRALER 471
>FGFR4_HUMAN (P22455) Fibroblast growth factor receptor 4 precursor (EC| 2.7.10.1) (FGFR-4) (CD334 antigen) Length = 802 Score = 33.5 bits (75), Expect = 0.56 Identities = 29/99 (29%), Positives = 46/99 (46%), Gaps = 1/99 (1%) Frame = -3 Query: 645 YTMKSDVYSFGVVMLELLT-GRKPFDSSKPRSEQSLVRWASPQLHDIDALDRMVDPALKG 469 YT +SDV+SFG+++ E+ T G P+ SL+R + H +D P L G Sbjct: 666 YTHQSDVWSFGILLWEIFTLGGSPYPGIPVEELFSLLR----EGHRMDRPPH-CPPELYG 720 Query: 468 LYPAKSLSRFADVLALCVQAEPEFRPPMSEVVQALVRLV 352 L + C A P RP ++V+AL +++ Sbjct: 721 L------------MRECWHAAPSQRPTFKQLVEALDKVL 747
>ERBB2_CANFA (O18735) Receptor tyrosine-protein kinase erbB-2 precursor (EC| 2.7.10.1) (p185erbB2) (C-erbB-2) Length = 1259 Score = 33.5 bits (75), Expect = 0.56 Identities = 22/59 (37%), Positives = 32/59 (54%), Gaps = 5/59 (8%) Frame = -3 Query: 648 QYTMKSDVYSFGVVMLELLT-GRKPFDSSKPRSEQSLV----RWASPQLHDIDALDRMV 487 ++T +SDV+S+GV + EL+T G KP+D R L+ R P + ID MV Sbjct: 897 RFTHQSDVWSYGVTVWELMTFGAKPYDGIPAREIPDLLEKGERLPQPPICTIDVYMIMV 955
>KS6A3_MOUSE (P18654) Ribosomal protein S6 kinase alpha-3 (EC 2.7.11.1)| (S6K-alpha 3) (90 kDa ribosomal protein S6 kinase 3) (p90-RSK 3) (Ribosomal S6 kinase 2) (RSK-2) (pp90RSK2) (MAP kinase-activated protein kinase 1b) (MAPKAPK1B) Length = 740 Score = 33.5 bits (75), Expect = 0.56 Identities = 13/36 (36%), Positives = 22/36 (61%) Frame = -3 Query: 645 YTMKSDVYSFGVVMLELLTGRKPFDSSKPRSEQSLV 538 +T +D +SFGV+M E+LTG PF + +++ Sbjct: 245 HTQSADWWSFGVLMFEMLTGTLPFQGKDRKETMTMI 280
>KS6A3_HUMAN (P51812) Ribosomal protein S6 kinase alpha-3 (EC 2.7.11.1)| (S6K-alpha 3) (90 kDa ribosomal protein S6 kinase 3) (p90-RSK 3) (Ribosomal S6 kinase 2) (RSK-2) (pp90RSK2) (Insulin-stimulated protein kinase 1) (ISPK-1) (MAP kinase-activated protei Length = 740 Score = 33.5 bits (75), Expect = 0.56 Identities = 13/36 (36%), Positives = 22/36 (61%) Frame = -3 Query: 645 YTMKSDVYSFGVVMLELLTGRKPFDSSKPRSEQSLV 538 +T +D +SFGV+M E+LTG PF + +++ Sbjct: 245 HTQSADWWSFGVLMFEMLTGTLPFQGKDRKETMTMI 280
>FYN_MOUSE (P39688) Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2)| (p59-Fyn) Length = 533 Score = 33.5 bits (75), Expect = 0.56 Identities = 15/32 (46%), Positives = 24/32 (75%), Gaps = 1/32 (3%) Frame = -3 Query: 648 QYTMKSDVYSFGVVMLELLT-GRKPFDSSKPR 556 ++T+KSDV+SFG+++ EL+T GR P+ R Sbjct: 438 RFTIKSDVWSFGILLTELVTKGRVPYPGMNNR 469
>FYN_CHICK (Q05876) Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2)| (p59-Fyn) Length = 533 Score = 33.5 bits (75), Expect = 0.56 Identities = 15/32 (46%), Positives = 24/32 (75%), Gaps = 1/32 (3%) Frame = -3 Query: 648 QYTMKSDVYSFGVVMLELLT-GRKPFDSSKPR 556 ++T+KSDV+SFG+++ EL+T GR P+ R Sbjct: 438 RFTIKSDVWSFGILLTELVTKGRVPYPGMNNR 469
>M3K1_HUMAN (Q13233) Mitogen-activated protein kinase kinase kinase 1 (EC| 2.7.11.25) (MAPK/ERK kinase kinase 1) (MEK kinase 1) (MEKK 1) (Fragment) Length = 1495 Score = 33.5 bits (75), Expect = 0.56 Identities = 20/93 (21%), Positives = 43/93 (46%) Frame = -3 Query: 648 QYTMKSDVYSFGVVMLELLTGRKPFDSSKPRSEQSLVRWASPQLHDIDALDRMVDPALKG 469 QY DV+S G ++E+ + P+++ K + +L+ + ++ + P L+ Sbjct: 1408 QYGRSCDVWSVGCAIIEMACAKPPWNAEKHSNHLALI-FKIASATTAPSIPSHLSPGLR- 1465 Query: 468 LYPAKSLSRFADVLALCVQAEPEFRPPMSEVVQ 370 DV C++ +P+ RPP E+++ Sbjct: 1466 -----------DVALRCLELQPQDRPPSRELLK 1487
>KCCS_MALDO (Q07250) Calcium/calmodulin-dependent serine/threonine-protein| kinase (EC 2.7.11.17) Length = 415 Score = 33.5 bits (75), Expect = 0.56 Identities = 14/37 (37%), Positives = 24/37 (64%) Frame = -3 Query: 648 QYTMKSDVYSFGVVMLELLTGRKPFDSSKPRSEQSLV 538 Q T KSD+++ GV++ LL+G PF + R +Q ++ Sbjct: 226 QVTSKSDMWALGVILYILLSGYPPFIAQSNRQKQQMI 262
>ERBB2_MOUSE (P70424) Receptor tyrosine-protein kinase erbB-2 precursor (EC| 2.7.10.1) (p185erbB2) (C-erbB-2) (NEU proto-oncogene) Length = 1256 Score = 33.5 bits (75), Expect = 0.56 Identities = 22/59 (37%), Positives = 32/59 (54%), Gaps = 5/59 (8%) Frame = -3 Query: 648 QYTMKSDVYSFGVVMLELLT-GRKPFDSSKPRSEQSLV----RWASPQLHDIDALDRMV 487 ++T +SDV+S+GV + EL+T G KP+D R L+ R P + ID MV Sbjct: 899 RFTHQSDVWSYGVTVWELMTFGAKPYDGIPAREIPDLLEKGERLPQPPICTIDVYMIMV 957
>ERBB2_MESAU (Q60553) Receptor tyrosine-protein kinase erbB-2 precursor (EC| 2.7.10.1) (p185erbB2) (C-erbB-2) (NEU proto-oncogene) Length = 1254 Score = 33.5 bits (75), Expect = 0.56 Identities = 22/59 (37%), Positives = 32/59 (54%), Gaps = 5/59 (8%) Frame = -3 Query: 648 QYTMKSDVYSFGVVMLELLT-GRKPFDSSKPRSEQSLV----RWASPQLHDIDALDRMV 487 ++T +SDV+S+GV + EL+T G KP+D R L+ R P + ID MV Sbjct: 898 RFTHQSDVWSYGVTVWELMTFGAKPYDGIPAREIPDLLEKGERLPQPPICTIDVYMIMV 956
>ERBB2_RAT (P06494) Receptor tyrosine-protein kinase erbB-2 precursor (EC| 2.7.10.1) (p185erbB2) (C-erbB-2) (NEU proto-oncogene) (Epidermal growth factor receptor-related protein) Length = 1257 Score = 33.5 bits (75), Expect = 0.56 Identities = 22/59 (37%), Positives = 32/59 (54%), Gaps = 5/59 (8%) Frame = -3 Query: 648 QYTMKSDVYSFGVVMLELLT-GRKPFDSSKPRSEQSLV----RWASPQLHDIDALDRMV 487 ++T +SDV+S+GV + EL+T G KP+D R L+ R P + ID MV Sbjct: 900 RFTHQSDVWSYGVTVWELMTFGAKPYDGIPAREIPDLLEKGERLPQPPICTIDVYMIMV 958
>MET_CANFA (Q75ZY9) Hepatocyte growth factor receptor precursor (EC 2.7.10.1)| (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met) Length = 1382 Score = 33.5 bits (75), Expect = 0.56 Identities = 28/98 (28%), Positives = 42/98 (42%), Gaps = 3/98 (3%) Frame = -3 Query: 648 QYTMKSDVYSFGVVMLELLTGRKPFDSSKPRSEQSLVRWASPQLHDIDALDRMVDPALKG 469 ++T KSDV+SFGV++ EL+T +P D++ D V L+G Sbjct: 1260 KFTTKSDVWSFGVLLWELMTR------------------GAPPYPDVNTFDITV-YLLQG 1300 Query: 468 ---LYPAKSLSRFADVLALCVQAEPEFRPPMSEVVQAL 364 L P +V+ C E RP SE+V + Sbjct: 1301 RRLLQPEYCPDPLYEVMLKCWHPRAELRPSFSELVSRI 1338
>M3K1_RAT (Q62925) Mitogen-activated protein kinase kinase kinase 1 (EC| 2.7.11.25) (MAPK/ERK kinase kinase 1) (MEK kinase 1) (MEKK 1) Length = 1493 Score = 33.5 bits (75), Expect = 0.56 Identities = 20/93 (21%), Positives = 43/93 (46%) Frame = -3 Query: 648 QYTMKSDVYSFGVVMLELLTGRKPFDSSKPRSEQSLVRWASPQLHDIDALDRMVDPALKG 469 QY DV+S G ++E+ + P+++ K + +L+ + ++ + P L+ Sbjct: 1406 QYGRSCDVWSVGCAIIEMACAKPPWNAEKHSNHLALI-FKIASATTAPSIPSHLSPGLR- 1463 Query: 468 LYPAKSLSRFADVLALCVQAEPEFRPPMSEVVQ 370 DV C++ +P+ RPP E+++ Sbjct: 1464 -----------DVALRCLELQPQDRPPSRELLK 1485
>RET_MOUSE (P35546) Proto-oncogene tyrosine-protein kinase receptor ret| precursor (EC 2.7.10.1) (C-ret) Length = 1115 Score = 33.5 bits (75), Expect = 0.56 Identities = 28/118 (23%), Positives = 56/118 (47%), Gaps = 1/118 (0%) Frame = -3 Query: 645 YTMKSDVYSFGVVMLELLT-GRKPFDSSKPRSEQSLVRWASPQLHDIDALDRMVDPALKG 469 YT +SDV+SFGV++ E++T G P+ P +L++ H ++ D + + Sbjct: 929 YTTQSDVWSFGVLLWEIVTLGGNPYPGIPPERLFNLLKTG----HRMERPDNCSEEMYR- 983 Query: 468 LYPAKSLSRFADVLALCVQAEPEFRPPMSEVVQALVRLVQRANMTKKMLDGDASRRGD 295 ++ C + EP+ RP +++ + L +++ + ++ LD AS D Sbjct: 984 ------------LMLQCWKQEPDKRPVFADISKDLEKMMVK---SRDYLDLAASTPSD 1026
>MET_PIG (Q2QLE0) Hepatocyte growth factor receptor precursor (EC 2.7.10.1)| (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met) Length = 1381 Score = 33.5 bits (75), Expect = 0.56 Identities = 28/98 (28%), Positives = 42/98 (42%), Gaps = 3/98 (3%) Frame = -3 Query: 648 QYTMKSDVYSFGVVMLELLTGRKPFDSSKPRSEQSLVRWASPQLHDIDALDRMVDPALKG 469 ++T KSDV+SFGV++ EL+T +P D++ D V L+G Sbjct: 1259 KFTTKSDVWSFGVLLWELMTR------------------GAPPYPDVNTFDITV-YLLQG 1299 Query: 468 ---LYPAKSLSRFADVLALCVQAEPEFRPPMSEVVQAL 364 L P +V+ C E RP SE+V + Sbjct: 1300 RRLLQPEYCPDPLYEVMLKCWHPRAELRPSFSELVSRI 1337
>YES_CHICK (P09324) Tyrosine-protein kinase Yes (EC 2.7.10.2) (p61-Yes)| Length = 540 Score = 33.5 bits (75), Expect = 0.56 Identities = 25/97 (25%), Positives = 50/97 (51%), Gaps = 1/97 (1%) Frame = -3 Query: 648 QYTMKSDVYSFGVVMLELLT-GRKPFDSSKPRSEQSLVRWASPQLHDIDALDRMVDPALK 472 ++T+KSDV+SFG+++ EL+T GR P+ P + + + L++ V+ + Sbjct: 445 RFTIKSDVWSFGILLTELVTKGRVPY----------------PGMVNREVLEQ-VERGYR 487 Query: 471 GLYPAKSLSRFADVLALCVQAEPEFRPPMSEVVQALV 361 P +++ LC + +P+ RP E +Q+ + Sbjct: 488 MPCPQGCPESLHELMKLCWKKDPDERPTF-EYIQSFL 523
>ERBB2_HUMAN (P04626) Receptor tyrosine-protein kinase erbB-2 precursor (EC| 2.7.10.1) (p185erbB2) (C-erbB-2) (NEU proto-oncogene) (Tyrosine kinase-type cell surface receptor HER2) (MLN 19) Length = 1255 Score = 33.5 bits (75), Expect = 0.56 Identities = 22/59 (37%), Positives = 32/59 (54%), Gaps = 5/59 (8%) Frame = -3 Query: 648 QYTMKSDVYSFGVVMLELLT-GRKPFDSSKPRSEQSLV----RWASPQLHDIDALDRMV 487 ++T +SDV+S+GV + EL+T G KP+D R L+ R P + ID MV Sbjct: 898 RFTHQSDVWSYGVTVWELMTFGAKPYDGIPAREIPDLLEKGERLPQPPICTIDVYMIMV 956
>EGFR_MOUSE (Q01279) Epidermal growth factor receptor precursor (EC 2.7.10.1)| Length = 1210 Score = 33.5 bits (75), Expect = 0.56 Identities = 24/59 (40%), Positives = 33/59 (55%), Gaps = 6/59 (10%) Frame = -3 Query: 645 YTMKSDVYSFGVVMLELLT-GRKPFDSSKPRSEQSLV-----RWASPQLHDIDALDRMV 487 YT +SDV+S+GV + EL+T G KP+D P S+ S + R P + ID MV Sbjct: 893 YTHQSDVWSYGVTVWELMTFGSKPYDGI-PASDISSILEKGERLPQPPICTIDVYMIMV 950
>ATG1_NEUCR (Q7RX99) Serine/threonine-protein kinase atg-1 (EC 2.7.11.1)| (Autophagy-related protein 1) Length = 932 Score = 33.5 bits (75), Expect = 0.56 Identities = 13/28 (46%), Positives = 21/28 (75%) Frame = -3 Query: 648 QYTMKSDVYSFGVVMLELLTGRKPFDSS 565 +Y K+D++S G V+ E++TGR PF +S Sbjct: 247 KYDAKADLWSVGTVLYEMVTGRPPFKAS 274
>TESK1_MOUSE (O70146) Dual specificity testis-specific protein kinase 1 (EC| 2.7.12.1) (Testicular protein kinase 1) Length = 627 Score = 33.5 bits (75), Expect = 0.56 Identities = 28/101 (27%), Positives = 45/101 (44%), Gaps = 1/101 (0%) Frame = -3 Query: 645 YTMKSDVYSFGVVMLELLTGRKPFDSS-KPRSEQSLVRWASPQLHDIDALDRMVDPALKG 469 Y K+DV++FG+V+ EL+ R P D PR+E +D PA + Sbjct: 229 YDEKADVFAFGIVLCELI-ARVPADPDYLPRTED----------FGLDV------PAFRT 271 Query: 468 LYPAKSLSRFADVLALCVQAEPEFRPPMSEVVQALVRLVQR 346 L F + C EP R P +E+ Q L +++++ Sbjct: 272 LVGNDCPLPFLLLAIHCCSMEPSTRAPFTEITQHLEQILEQ 312
>YES_XENLA (P10936) Tyrosine-protein kinase Yes (EC 2.7.10.2) (p61-Yes)| Length = 536 Score = 33.1 bits (74), Expect = 0.73 Identities = 24/97 (24%), Positives = 50/97 (51%), Gaps = 1/97 (1%) Frame = -3 Query: 648 QYTMKSDVYSFGVVMLELLT-GRKPFDSSKPRSEQSLVRWASPQLHDIDALDRMVDPALK 472 ++T+KSDV+SFG+++ EL+ GR P+ P + + + L++ V+ + Sbjct: 441 RFTIKSDVWSFGILLTELVAKGRVPY----------------PGMVNREVLEQ-VERGYR 483 Query: 471 GLYPAKSLSRFADVLALCVQAEPEFRPPMSEVVQALV 361 P + +++ LC + +P+ RP E +Q+ + Sbjct: 484 MPCPQRCPESLHELMKLCWKKDPDERPTF-EYIQSFL 519
>RYK_MOUSE (Q01887) Tyrosine-protein kinase RYK precursor (EC 2.7.10.1)| (Kinase VIK) (NYK-R) (Met-related kinase) Length = 594 Score = 33.1 bits (74), Expect = 0.73 Identities = 26/96 (27%), Positives = 44/96 (45%), Gaps = 1/96 (1%) Frame = -3 Query: 648 QYTMKSDVYSFGVVMLELLT-GRKPFDSSKPRSEQSLVRWASPQLHDIDALDRMVDPALK 472 +++ SDV++FGV + EL+T G+ P+ P + ++ I+ D + Sbjct: 505 EFSSASDVWAFGVTLWELMTLGQTPYVDIDPFEMAAYLKDGYRIAQPINCPDEL------ 558 Query: 471 GLYPAKSLSRFADVLALCVQAEPEFRPPMSEVVQAL 364 FA V+A C +PE RP ++VQ L Sbjct: 559 ----------FA-VMACCWALDPEERPKFQQLVQCL 583
>ULK1_MOUSE (O70405) Serine/threonine-protein kinase ULK1 (EC 2.7.11.1)| (Unc-51-like kinase 1) (Serine/threonine-protein kinase Unc51.1) Length = 1051 Score = 33.1 bits (74), Expect = 0.73 Identities = 12/30 (40%), Positives = 21/30 (70%) Frame = -3 Query: 645 YTMKSDVYSFGVVMLELLTGRKPFDSSKPR 556 Y K+D++S G ++ + LTG+ PF +S P+ Sbjct: 198 YDGKADLWSIGTIVYQCLTGKAPFQASSPQ 227
>ULK1_HUMAN (O75385) Serine/threonine-protein kinase ULK1 (EC 2.7.11.1)| (Unc-51-like kinase 1) Length = 1050 Score = 33.1 bits (74), Expect = 0.73 Identities = 12/30 (40%), Positives = 21/30 (70%) Frame = -3 Query: 645 YTMKSDVYSFGVVMLELLTGRKPFDSSKPR 556 Y K+D++S G ++ + LTG+ PF +S P+ Sbjct: 198 YDGKADLWSIGTIVYQCLTGKAPFQASSPQ 227
>STK10_MOUSE (O55098) Serine/threonine-protein kinase 10 (EC 2.7.11.1)| (Lymphocyte-oriented kinase) Length = 966 Score = 33.1 bits (74), Expect = 0.73 Identities = 32/137 (23%), Positives = 57/137 (41%), Gaps = 13/137 (9%) Frame = -3 Query: 645 YTMKSDVYSFGVVMLELLTGRKPFDSSKPRSEQSLVRWASPQLHDIDALDRMVDPALKGL 466 Y K+D++S G+ ++E+ P P + + P P L L Sbjct: 214 YDYKADIWSLGITLIEMAQIEPPHHELNPMRVLLKIAKSDP-------------PTL--L 258 Query: 465 YPAKSLSRFADVLALCVQAEPEFRPPMSEVVQ-----------ALVRLV--QRANMTKKM 325 P+K F D L + + PE RP ++++Q AL LV +A + +++ Sbjct: 259 TPSKWSVEFRDFLKIALDKNPETRPSAAQLLQHPFVSRVTSNKALRELVAEAKAEVMEEI 318 Query: 324 LDGDASRRGDDQDQDFI 274 DG R D +++D + Sbjct: 319 EDG----REDGEEEDAV 331
>MP2K2_XENLA (Q07192) Dual specificity mitogen-activated protein kinase kinase 2| (EC 2.7.12.2) (MAP kinase kinase 2) (MAPKK 2) (MAPK-ERK kinase 2) (Fragment) Length = 446 Score = 33.1 bits (74), Expect = 0.73 Identities = 24/94 (25%), Positives = 43/94 (45%), Gaps = 2/94 (2%) Frame = -3 Query: 645 YTMKSDVYSFGVVMLELLTGRKPFDSSKPRSEQ--SLVRWASPQLHDIDALDRMVDPALK 472 Y ++SDV+S G+ + EL TGR P+ +Q +V+ PQL + + +R P+ Sbjct: 331 YDVRSDVWSLGITLYELATGRFPYPKWNSVFDQLTQVVKGDPPQLSNSE--EREFSPS-- 386 Query: 471 GLYPAKSLSRFADVLALCVQAEPEFRPPMSEVVQ 370 F + C+ + RP E+++ Sbjct: 387 ----------FTSFVNQCLTKDESKRPKYKELLK 410
>RYK_HUMAN (P34925) Tyrosine-protein kinase RYK precursor (EC 2.7.10.1)| Length = 604 Score = 33.1 bits (74), Expect = 0.73 Identities = 26/96 (27%), Positives = 44/96 (45%), Gaps = 1/96 (1%) Frame = -3 Query: 648 QYTMKSDVYSFGVVMLELLT-GRKPFDSSKPRSEQSLVRWASPQLHDIDALDRMVDPALK 472 +++ SDV++FGV + EL+T G+ P+ P + ++ I+ D + Sbjct: 515 EFSSASDVWAFGVTLWELMTLGQTPYVDIDPFEMAAYLKDGYRIAQPINCPDEL------ 568 Query: 471 GLYPAKSLSRFADVLALCVQAEPEFRPPMSEVVQAL 364 FA V+A C +PE RP ++VQ L Sbjct: 569 ----------FA-VMACCWALDPEERPKFQQLVQCL 593 Database: uniprot_sprot.fasta Posted date: May 25, 2006 5:36 PM Number of letters in database: 80,573,946 Number of sequences in database: 219,361 Lambda K H 0.318 0.135 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 96,178,196 Number of Sequences: 219361 Number of extensions: 2032773 Number of successful extensions: 7766 Number of sequences better than 10.0: 500 Number of HSP's better than 10.0 without gapping: 7318 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 7711 length of database: 80,573,946 effective HSP length: 108 effective length of database: 56,882,958 effective search space used: 6143359464 frameshift window, decay const: 50, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
