ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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| Clone Name | rbasd22h06 |
|---|---|
| Clone Library Name | barley_pub |
>SIRK_ARATH (O64483) Senescence-induced receptor-like serine/threonine-protein| kinase precursor (FLG22-induced receptor-like kinase 1) Length = 876 Score = 141 bits (356), Expect = 1e-33 Identities = 74/143 (51%), Positives = 98/143 (68%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTHATTRPMGTSGYLDPEYYATSHLSEKSDVYSFGI 387 ILL L+A+++DFGL+R+FS E S +T G+ GYLDPEYY+T ++EKSDVYS G+ Sbjct: 703 ILLNEKLQAKMADFGLSRSFSVEGSGQISTVVAGSIGYLDPEYYSTRQMNEKSDVYSLGV 762 Query: 386 LLLVLITAQPVIVTANNAKRENISLWVRSRLLEGDIESLTDLRIRGHYDVNSVWKVAEMA 207 +LL +IT QP I ++ K +IS VRS L GDI + D R+R YDV S WK++E+A Sbjct: 763 VLLEVITGQPAIASSKTEK-VHISDHVRSILANGDIRGIVDQRLRERYDVGSAWKMSEIA 821 Query: 206 LHCTEHKRQDRPTMMEVVEGLKE 138 L CTEH RPTM +VV LK+ Sbjct: 822 LACTEHTSAQRPTMSQVVMELKQ 844
>NORK_MEDTR (Q8L4H4) Nodulation receptor kinase precursor (EC 2.7.11.1) (Does not| make infections protein 2) (Symbiosis receptor-like kinase) (MtSYMRK) Length = 925 Score = 108 bits (270), Expect = 1e-23 Identities = 55/155 (35%), Positives = 91/155 (58%), Gaps = 4/155 (2%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTHATTRPMGTSGYLDPEYYATSHLSEKSDVYSFGI 387 ILL + A+++DFG ++ E ++ + GT+GYLDPEYY T LSEKSDV+SFG+ Sbjct: 728 ILLDQSMCAKVADFGFSKYAPQEGDSYVSLEVRGTAGYLDPEYYKTQQLSEKSDVFSFGV 787 Query: 386 LLLVLITAQPVIVTANNAKRENISL----WVRSRLLEGDIESLTDLRIRGHYDVNSVWKV 219 +LL +++ + + N KR I W + + ++ + D I+G Y ++W+V Sbjct: 788 VLLEIVSGREPL----NIKRPRIEWSLVEWAKPYIRASKVDEIVDPGIKGGYHAEALWRV 843 Query: 218 AEMALHCTEHKRQDRPTMMEVVEGLKEGLQLENSS 114 E+AL C E RP M+++V L++ L +EN++ Sbjct: 844 VEVALQCLEPYSTYRPCMVDIVRELEDALIIENNA 878
>NORK_PEA (Q8LKZ1) Nodulation receptor kinase precursor (EC 2.7.11.1)| Length = 924 Score = 107 bits (268), Expect = 2e-23 Identities = 51/151 (33%), Positives = 89/151 (58%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTHATTRPMGTSGYLDPEYYATSHLSEKSDVYSFGI 387 ILL + A+++DFG ++ E ++ + GT+GYLDPEYY T LSEKSDV+SFG+ Sbjct: 727 ILLDHSMCAKVADFGFSKYAPQEGDSYVSLEVRGTAGYLDPEYYKTQQLSEKSDVFSFGV 786 Query: 386 LLLVLITAQPVIVTANNAKRENISLWVRSRLLEGDIESLTDLRIRGHYDVNSVWKVAEMA 207 +LL +++ + + ++ W + + ++ + D I+G Y ++W+V E+A Sbjct: 787 VLLEIVSGREPLNIKRPRVEWSLVEWAKPYIRASKVDEIVDPGIKGGYHAEALWRVVEVA 846 Query: 206 LHCTEHKRQDRPTMMEVVEGLKEGLQLENSS 114 L C E RP M+++V L++ L +EN++ Sbjct: 847 LQCLEPYSTYRPCMVDIVRELEDALIIENNA 877
>NAK_ARATH (P43293) Probable serine/threonine-protein kinase NAK (EC 2.7.11.1)| Length = 389 Score = 105 bits (262), Expect = 9e-23 Identities = 58/144 (40%), Positives = 84/144 (58%), Gaps = 1/144 (0%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTHATTRPMGTSGYLDPEYYATSHLSEKSDVYSFGI 387 ILL ++ A++SDFGL R ++H +TR MGT GY PEY AT HLS KSDVYSFG+ Sbjct: 209 ILLDSNYNAKLSDFGLARDGPMGDNSHVSTRVMGTQGYAAPEYLATGHLSVKSDVYSFGV 268 Query: 386 LLLVLITAQPVIVTANNAKRENISLWVRSRLL-EGDIESLTDLRIRGHYDVNSVWKVAEM 210 +LL L++ + I N+ W R L + + + D R++G Y + K+A + Sbjct: 269 VLLELLSGRRAIDKNQPVGEHNLVDWARPYLTNKRRLLRVMDPRLQGQYSLTRALKIAVL 328 Query: 209 ALHCTEHKRQDRPTMMEVVEGLKE 138 AL C + RPTM E+V+ ++E Sbjct: 329 ALDCISIDAKSRPTMNEIVKTMEE 352
>CX32_ARATH (P27450) Probable serine/threonine-protein kinase Cx32, chloroplast| precursor (EC 2.7.11.1) Length = 419 Score = 104 bits (260), Expect = 2e-22 Identities = 67/172 (38%), Positives = 100/172 (58%), Gaps = 18/172 (10%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTHATTRPMGTSGYLDPEYYATSHLSEKSDVYSFGI 387 ILL ++ +A++SDFGL + ++ +H TTR MGT GY PEY AT HL KSDV++FG+ Sbjct: 224 ILLDSNYDAKLSDFGLAKLGPADEKSHVTTRIMGTYGYAAPEYMATGHLYVKSDVFAFGV 283 Query: 386 LLLVLITAQPVIVTANNAKR----ENISLWVRSRLL-EGDIESLTDLRIRGHYDVNSVWK 222 +LL ++T +TA+N KR E++ W+R L + ++ + D I+G Y + Sbjct: 284 VLLEIMTG----LTAHNTKRPRGQESLVDWLRPELSNKHRVKQIMDKGIKGQYTTKVATE 339 Query: 221 VAEMALHCTEHKRQDRPTMMEVVEGLK--EGLQ-----------LENSSRSS 105 +A + L C E ++RP M EVVE L+ +GL + NSSRSS Sbjct: 340 MARITLSCIEPDPKNRPHMKEVVEVLEHIQGLNVVPNRSSTKQAVANSSRSS 391
>BAK1_ARATH (Q94F62) BRASSINOSTEROID INSENSITIVE 1-associated receptor kinase 1| precursor (EC 2.7.11.1) (BRI1-associated receptor kinase 1) (Somatic embryogenesis receptor-like kinase 3) Length = 615 Score = 101 bits (251), Expect = 2e-21 Identities = 56/144 (38%), Positives = 85/144 (59%), Gaps = 2/144 (1%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTHATTRPMGTSGYLDPEYYATSHLSEKSDVYSFGI 387 ILL + EA + DFGL + + TH TT GT G++ PEY +T SEK+DV+ +G+ Sbjct: 422 ILLDEEFEAVVGDFGLAKLMDYK-DTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFGYGV 480 Query: 386 LLLVLITAQPVIVTANNAKRENISL--WVRSRLLEGDIESLTDLRIRGHYDVNSVWKVAE 213 +LL LIT Q A A +++ L WV+ L E +E+L D+ ++G+Y V ++ + Sbjct: 481 MLLELITGQRAFDLARLANDDDVMLLDWVKGLLKEKKLEALVDVDLQGNYKDEEVEQLIQ 540 Query: 212 MALHCTEHKRQDRPTMMEVVEGLK 141 +AL CT+ +RP M EVV L+ Sbjct: 541 VALLCTQSSPMERPKMSEVVRMLE 564
>APK1A_ARATH (Q06548) Protein kinase APK1A, chloroplast precursor (EC 2.7.11.1)| Length = 410 Score = 97.4 bits (241), Expect = 2e-20 Identities = 54/143 (37%), Positives = 82/143 (57%), Gaps = 1/143 (0%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTHATTRPMGTSGYLDPEYYATSHLSEKSDVYSFGI 387 ILL ++ A++SDFGL + +H +TR MGT GY PEY AT HL+ KSDVYSFG+ Sbjct: 209 ILLDSEYNAKLSDFGLAKDGPIGDKSHVSTRVMGTHGYAAPEYLATGHLTTKSDVYSFGV 268 Query: 386 LLLVLITAQPVIVTANNAKRENISLWVRSRLL-EGDIESLTDLRIRGHYDVNSVWKVAEM 210 +LL L++ + + + N+ W + L+ + I + D R++ Y + KVA + Sbjct: 269 VLLELLSGRRAVDKNRPSGERNLVEWAKPYLVNKRKIFRVIDNRLQDQYSMEEACKVATL 328 Query: 209 ALHCTEHKRQDRPTMMEVVEGLK 141 +L C + + RP M EVV L+ Sbjct: 329 SLRCLTTEIKLRPNMSEVVSHLE 351
>CRI4_MAIZE (O24585) Putative receptor protein kinase CRINKLY4 precursor (EC| 2.7.11.1) Length = 901 Score = 94.7 bits (234), Expect = 2e-19 Identities = 53/147 (36%), Positives = 83/147 (56%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTHATTRPMGTSGYLDPEYYATSHLSEKSDVYSFGI 387 IL+ D AR++DFGL+ ++ T + P GT GYLDPEYY +L+ KSDVYSFG+ Sbjct: 640 ILIDEDHNARVADFGLSILGPADSGTPLSELPAGTLGYLDPEYYRLHYLTTKSDVYSFGV 699 Query: 386 LLLVLITAQPVIVTANNAKRENISLWVRSRLLEGDIESLTDLRIRGHYDVNSVWKVAEMA 207 +LL +++ + I + NI W + GDI ++ D + D+ ++ K+A +A Sbjct: 700 VLLEILSGRKAI--DMQFEEGNIVEWAVPLIKAGDIFAILDPVLSPPSDLEALKKIASVA 757 Query: 206 LHCTEHKRQDRPTMMEVVEGLKEGLQL 126 C + +DRP+M +V L+ L L Sbjct: 758 CKCVRMRGKDRPSMDKVTTALEHALAL 784
>APK1B_ARATH (P46573) Protein kinase APK1B, chloroplast precursor (EC 2.7.11.1)| Length = 412 Score = 94.4 bits (233), Expect = 2e-19 Identities = 53/157 (33%), Positives = 86/157 (54%), Gaps = 1/157 (0%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTHATTRPMGTSGYLDPEYYATSHLSEKSDVYSFGI 387 ILL ++ A++SDFGL + + +H +TR MGT GY PEY AT HL+ KSDVYS+G+ Sbjct: 210 ILLDSEYNAKLSDFGLAKDGPTGDKSHVSTRIMGTYGYAAPEYLATGHLTTKSDVYSYGV 269 Query: 386 LLLVLITAQPVIVTANNAKRENISLWVRSRLL-EGDIESLTDLRIRGHYDVNSVWKVAEM 210 +LL +++ + + + + W R L + + + D R++ Y + KVA + Sbjct: 270 VLLEVLSGRRAVDKNRPPGEQKLVEWARPLLANKRKLFRVIDNRLQDQYSMEEACKVATL 329 Query: 209 ALHCTEHKRQDRPTMMEVVEGLKEGLQLENSSRSSVE 99 AL C + + RP M EVV L+ L + +++ Sbjct: 330 ALRCLTFEIKLRPNMNEVVSHLEHIQTLNEAGGRNID 366
>RLCK7_ARATH (Q9LQQ8) Probable serine/threonine-protein kinase RLCKVII (EC| 2.7.11.1) Length = 423 Score = 93.2 bits (230), Expect = 5e-19 Identities = 50/142 (35%), Positives = 77/142 (54%), Gaps = 1/142 (0%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTHATTRPMGTSGYLDPEYYATSHLSEKSDVYSFGI 387 ILL D + ++SDFGL + S TH +TR MGT GY P+Y T L+ KSD+YSFG+ Sbjct: 236 ILLGEDYQPKLSDFGLAKVGPSGDKTHVSTRVMGTYGYCAPDYAMTGQLTFKSDIYSFGV 295 Query: 386 LLLVLITAQPVIVTANNAKRENISLWVRSRLLE-GDIESLTDLRIRGHYDVNSVWKVAEM 210 +LL LIT + I K +N+ W R + + + D ++G Y V +++ + Sbjct: 296 VLLELITGRKAIDNTKTRKDQNLVGWARPLFKDRRNFPKMVDPLLQGQYPVRGLYQALAI 355 Query: 209 ALHCTEHKRQDRPTMMEVVEGL 144 + C + + RP + +VV L Sbjct: 356 SAMCVQEQPTMRPVVSDVVLAL 377
>PBS1_ARATH (Q9FE20) Serine/threonine-protein kinase PBS1 (EC 2.7.11.1)| (AvrPphB susceptible protein 1) Length = 456 Score = 86.3 bits (212), Expect = 6e-17 Identities = 48/142 (33%), Positives = 74/142 (52%), Gaps = 1/142 (0%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTHATTRPMGTSGYLDPEYYATSHLSEKSDVYSFGI 387 ILL ++SDFGL + + +H +TR MGT GY PEY T L+ KSDVYSFG+ Sbjct: 219 ILLDEGFHPKLSDFGLAKLGPTGDKSHVSTRVMGTYGYCAPEYAMTGQLTVKSDVYSFGV 278 Query: 386 LLLVLITAQPVIVTANNAKRENISLWVRSRLLE-GDIESLTDLRIRGHYDVNSVWKVAEM 210 + L LIT + I + +N+ W R + L D R++G + ++++ + Sbjct: 279 VFLELITGRKAIDSEMPHGEQNLVAWARPLFNDRRKFIKLADPRLKGRFPTRALYQALAV 338 Query: 209 ALHCTEHKRQDRPTMMEVVEGL 144 A C + + RP + +VV L Sbjct: 339 ASMCIQEQAATRPLIADVVTAL 360
>EXS_ARATH (Q9LYN8) Leucine-rich repeat receptor protein kinase EXS precursor| (EC 2.7.11.1) (Extra sporogenous cells protein) (EXCESS MICROSPOROCYTES1 protein) Length = 1192 Score = 81.6 bits (200), Expect = 1e-15 Identities = 47/144 (32%), Positives = 78/144 (54%), Gaps = 1/144 (0%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTHATTRPMGTSGYLDPEYYATSHLSEKSDVYSFGI 387 ILL D E +++DFGL R S+ +H +T GT GY+ PEY ++ + K DVYSFG+ Sbjct: 1049 ILLDGDFEPKVADFGLARLISA-CESHVSTVIAGTFGYIPPEYGQSARATTKGDVYSFGV 1107 Query: 386 LLLVLITA-QPVIVTANNAKRENISLWVRSRLLEGDIESLTDLRIRGHYDVNSVWKVAEM 210 +LL L+T +P ++ N+ W ++ +G + D + NS ++ ++ Sbjct: 1108 ILLELVTGKEPTGPDFKESEGGNLVGWAIQKINQGKAVDVIDPLLVSVALKNSQLRLLQI 1167 Query: 209 ALHCTEHKRQDRPTMMEVVEGLKE 138 A+ C RP M++V++ LKE Sbjct: 1168 AMLCLAETPAKRPNMLDVLKALKE 1191
>CLV1_ARATH (Q9SYQ8) Receptor protein kinase CLAVATA1 precursor (EC 2.7.11.1)| Length = 980 Score = 81.3 bits (199), Expect = 2e-15 Identities = 53/148 (35%), Positives = 79/148 (53%), Gaps = 7/148 (4%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTHATTRPMGTSGYLDPEYYATSHLSEKSDVYSFGI 387 ILL +D EA ++DFGL + ++ + G+ GY+ PEY T + EKSDVYSFG+ Sbjct: 823 ILLDSDFEAHVADFGLAKFLVDGAASECMSSIAGSYGYIAPEYAYTLKVDEKSDVYSFGV 882 Query: 386 LLLVLITAQPVIVTANNAKRENISLWVRSRLLE-------GDIESLTDLRIRGHYDVNSV 228 +LL LI + + + +I WVR+ E + ++ D R+ G Y + SV Sbjct: 883 VLLELIAGKKPV--GEFGEGVDIVRWVRNTEEEITQPSDAAIVVAIVDPRLTG-YPLTSV 939 Query: 227 WKVAEMALHCTEHKRQDRPTMMEVVEGL 144 V ++A+ C E + RPTM EVV L Sbjct: 940 IHVFKIAMMCVEEEAAARPTMREVVHML 967
>BRL2_ARATH (Q9ZPS9) Serine/threonine-protein kinase BRI1-like 2 precursor (EC| 2.7.11.1) (BRASSINOSTEROID INSENSITIVE 1-like protein 2) (Protein VASCULAR HIGHWAY 1) Length = 1143 Score = 80.9 bits (198), Expect = 2e-15 Identities = 55/168 (32%), Positives = 86/168 (51%), Gaps = 15/168 (8%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTHATTRPM-GTSGYLDPEYYATSHLSEKSDVYSFG 390 +LL D+EAR+SDFG+ R S+ + TH + + GT GY+ PEYY + + K DVYS G Sbjct: 972 VLLDQDMEARVSDFGMARLISA-LDTHLSVSTLAGTPGYVPPEYYQSFRCTAKGDVYSIG 1030 Query: 389 ILLLVLITAQ-----------PVIVTANNAKRENISLWV--RSRLLEGDIESLTDLR-IR 252 +++L +++ + ++ + RE + V L EG ESL + Sbjct: 1031 VVMLEILSGKRPTDKEEFGDTNLVGWSKMKAREGKHMEVIDEDLLKEGSSESLNEKEGFE 1090 Query: 251 GHYDVNSVWKVAEMALHCTEHKRQDRPTMMEVVEGLKEGLQLENSSRS 108 G V + + E+AL C + RP M++VV L+E EN+S S Sbjct: 1091 GGVIVKEMLRYLEIALRCVDDFPSKRPNMLQVVASLRELRGSENNSHS 1138
>RPK1_IPONI (P93194) Receptor-like protein kinase precursor (EC 2.7.11.1)| Length = 1109 Score = 80.5 bits (197), Expect = 3e-15 Identities = 51/146 (34%), Positives = 80/146 (54%), Gaps = 5/146 (3%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTHATTRPMGTSGYLDPEYYATSHLSEKSDVYSFGI 387 ILL +DLE ISDFG+ + ++ + GT GY+ PE T+ S +SDVYS+G+ Sbjct: 948 ILLDSDLEPHISDFGIAKLLDQSATSIPSNTVQGTIGYMAPENAFTTVKSRESDVYSYGV 1007 Query: 386 LLLVLITAQPVIVTANNAKRENISLWVRSRLLE-GDIESLTDLRIRGHYDVNSVW----K 222 +LL LIT + + + N + + + WVRS + G+I+ + D + +SV + Sbjct: 1008 VLLELITRKKALDPSFNGETDIVG-WVRSVWTQTGEIQKIVDPSLLDELIDSSVMEQVTE 1066 Query: 221 VAEMALHCTEHKRQDRPTMMEVVEGL 144 +AL C E + RPTM +VV+ L Sbjct: 1067 ALSLALRCAEKEVDKRPTMRDVVKQL 1092
>BRI1_LYCPE (Q8L899) Systemin receptor SR160 precursor (EC 2.7.11.1)| (Brassinosteroid LRR receptor kinase) Length = 1207 Score = 76.6 bits (187), Expect = 4e-14 Identities = 51/147 (34%), Positives = 83/147 (56%), Gaps = 4/147 (2%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTHATTRPM-GTSGYLDPEYYATSHLSEKSDVYSFG 390 +LL +LEAR+SDFG+ R S+ M TH + + GT GY+ PEYY + S K DVYS+G Sbjct: 1020 VLLDENLEARVSDFGMARLMSA-MDTHLSVSTLAGTPGYVPPEYYQSFRCSTKGDVYSYG 1078 Query: 389 ILLLVLITAQPVIVTANNAKRENISLWVRSRLLEGDIESLTD---LRIRGHYDVNSVWKV 219 ++LL L+T + +A+ N+ WV+ +G I + D L+ ++ + + Sbjct: 1079 VVLLELLTGKQPTDSADFGD-NNLVGWVKLH-AKGKITDVFDRELLKEDASIEIELLQHL 1136 Query: 218 AEMALHCTEHKRQDRPTMMEVVEGLKE 138 ++A C + + RPTM++V+ KE Sbjct: 1137 -KVACACLDDRHWKRPTMIQVMAMFKE 1162
>BRI1_LYCES (Q8GUQ5) Brassinosteroid LRR receptor kinase precursor (EC 2.7.11.1)| (tBRI1) (Altered brassinolide sensitivity 1) (Systemin receptor SR160) Length = 1207 Score = 76.6 bits (187), Expect = 4e-14 Identities = 51/147 (34%), Positives = 83/147 (56%), Gaps = 4/147 (2%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTHATTRPM-GTSGYLDPEYYATSHLSEKSDVYSFG 390 +LL +LEAR+SDFG+ R S+ M TH + + GT GY+ PEYY + S K DVYS+G Sbjct: 1020 VLLDENLEARVSDFGMARLMSA-MDTHLSVSTLAGTPGYVPPEYYQSFRCSTKGDVYSYG 1078 Query: 389 ILLLVLITAQPVIVTANNAKRENISLWVRSRLLEGDIESLTD---LRIRGHYDVNSVWKV 219 ++LL L+T + +A+ N+ WV+ +G I + D L+ ++ + + Sbjct: 1079 VVLLELLTGKQPTDSADFGD-NNLVGWVKLH-AKGKITDVFDRELLKEDASIEIELLQHL 1136 Query: 218 AEMALHCTEHKRQDRPTMMEVVEGLKE 138 ++A C + + RPTM++V+ KE Sbjct: 1137 -KVACACLDDRHWKRPTMIQVMAMFKE 1162
>TMK1_ARATH (P43298) Putative receptor protein kinase TMK1 precursor (EC| 2.7.11.1) Length = 942 Score = 75.9 bits (185), Expect = 8e-14 Identities = 53/159 (33%), Positives = 78/159 (49%), Gaps = 3/159 (1%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTHATTRPMGTSGYLDPEYYATSHLSEKSDVYSFGI 387 ILL D+ A+++DFGL R + E TR GT GYL PEY T ++ K DVYSFG+ Sbjct: 723 ILLGDDMRAKVADFGLVR-LAPEGKGSIETRIAGTFGYLAPEYAVTGRVTTKVDVYSFGV 781 Query: 386 LLLVLITAQPVIVTANNAKRENISLWVRSRLL--EGDIESLTDLRI-RGHYDVNSVWKVA 216 +L+ LIT + + + + ++ W + + E + D I + SV VA Sbjct: 782 ILMELITGRKSLDESQPEESIHLVSWFKRMYINKEASFKKAIDTTIDLDEETLASVHTVA 841 Query: 215 EMALHCTEHKRQDRPTMMEVVEGLKEGLQLENSSRSSVE 99 E+A HC + RP M V L ++L S + E Sbjct: 842 ELAGHCCAREPYQRPDMGHAVNILSSLVELWKPSDQNPE 880
>BRL3_ARATH (Q9LJF3) Serine/threonine-protein kinase BRI1-like 3 precursor (EC| 2.7.11.1) (BRASSINOSTEROID INSENSITIVE 1-like protein 3) Length = 1164 Score = 75.9 bits (185), Expect = 8e-14 Identities = 51/160 (31%), Positives = 83/160 (51%), Gaps = 7/160 (4%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTHATTRPM-GTSGYLDPEYYATSHLSEKSDVYSFG 390 +LL D AR+SDFG+ R S+ + TH + + GT GY+ PEYY + + K DVYS+G Sbjct: 991 VLLDQDFVARVSDFGMARLVSA-LDTHLSVSTLAGTPGYVPPEYYQSFRCTAKGDVYSYG 1049 Query: 389 ILLLVLITAQPVIVTANNAKRENISLWVRSRLLEG------DIESLTDLRIRGHYDVNSV 228 ++LL L++ + I + N+ W + E D E +TD G ++ Sbjct: 1050 VILLELLSGKKPIDPEEFGEDNNLVGWAKQLYREKRGAEILDPELVTDK--SGDVELLHY 1107 Query: 227 WKVAEMALHCTEHKRQDRPTMMEVVEGLKEGLQLENSSRS 108 K+A C + + RPTM++V+ KE +Q++ + S Sbjct: 1108 LKIAS---QCLDDRPFKRPTMIQVMTMFKELVQVDTENDS 1144
>PSKR_ARATH (Q9ZVR7) Putative phytosulfokine receptor precursor (EC 2.7.11.1)| (Phytosulfokine LRR receptor kinase) Length = 1008 Score = 75.1 bits (183), Expect = 1e-13 Identities = 50/144 (34%), Positives = 74/144 (51%), Gaps = 1/144 (0%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTHATTRPMGTSGYLDPEYYATSHLSEKSDVYSFGI 387 ILL + + ++DFGL R S TH +T +GT GY+ PEY S + K DVYSFG+ Sbjct: 866 ILLDENFNSHLADFGLARLMSP-YETHVSTDLVGTLGYIPPEYGQASVATYKGDVYSFGV 924 Query: 386 LLLVLIT-AQPVIVTANNAKRENISLWVRSRLLEGDIESLTDLRIRGHYDVNSVWKVAEM 210 +LL L+T +PV + R+ IS WV E + D I + +++V E+ Sbjct: 925 VLLELLTDKRPVDMCKPKGCRDLIS-WVVKMKHESRASEVFDPLIYSKENDKEMFRVLEI 983 Query: 209 ALHCTEHKRQDRPTMMEVVEGLKE 138 A C + RPT ++V L + Sbjct: 984 ACLCLSENPKQRPTTQQLVSWLDD 1007
>BRI1_ARATH (O22476) BRASSINOSTEROID INSENSITIVE 1 precursor (EC 2.7.11.1)| (AtBRI1) (Brassinosteroid LRR receptor kinase) Length = 1196 Score = 75.1 bits (183), Expect = 1e-13 Identities = 56/174 (32%), Positives = 87/174 (50%), Gaps = 16/174 (9%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTHATTRPM-GTSGYLDPEYYATSHLSEKSDVYSFG 390 +LL +LEAR+SDFG+ R S+ M TH + + GT GY+ PEYY + S K DVYS+G Sbjct: 1015 VLLDENLEARVSDFGMARLMSA-MDTHLSVSTLAGTPGYVPPEYYQSFRCSTKGDVYSYG 1073 Query: 389 ILLLVLITAQPVIVTANNAKRENISLWVRSRLLEGDIESLTDLRIRGHYDVN-------- 234 ++LL L+T KR S L G ++ LRI +D Sbjct: 1074 VVLLELLT----------GKRPTDSPDFGDNNLVGWVKQHAKLRISDVFDPELMKEDPAL 1123 Query: 233 --SVWKVAEMALHCTEHKRQDRPTMMEVVEGLKE-----GLQLENSSRSSVETG 93 + + ++A+ C + + RPTM++V+ KE G+ +++ RS + G Sbjct: 1124 EIELLQHLKVAVACLDDRAWRRPTMVQVMAMFKEIQAGSGIDSQSTIRSIEDGG 1177
>RLK5_ARATH (P47735) Receptor-like protein kinase 5 precursor (EC 2.7.11.1)| Length = 999 Score = 74.7 bits (182), Expect = 2e-13 Identities = 52/150 (34%), Positives = 83/150 (55%), Gaps = 7/150 (4%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRA--FSSEMSTHATTRPMGTSGYLDPEYYATSHLSEKSDVYSF 393 ILL +D A+++DFG+ + S + A + G+ GY+ PEY T ++EKSD+YSF Sbjct: 825 ILLDSDYGAKVADFGIAKVGQMSGSKTPEAMSGIAGSCGYIAPEYVYTLRVNEKSDIYSF 884 Query: 392 GILLLVLITA-QPVIVTANNAKRENISLWVRSRL----LEGDIESLTDLRIRGHYDVNSV 228 G++LL L+T QP T + ++++ WV + L LE I+ DL+ + + Sbjct: 885 GVVLLELVTGKQP---TDSELGDKDMAKWVCTALDKCGLEPVIDPKLDLKFK-----EEI 936 Query: 227 WKVAEMALHCTEHKRQDRPTMMEVVEGLKE 138 KV + L CT +RP+M +VV L+E Sbjct: 937 SKVIHIGLLCTSPLPLNRPSMRKVVIMLQE 966
>BRL1_ARATH (Q9ZWC8) Serine/threonine-protein kinase BRI1-like 1 precursor (EC| 2.7.11.1) (BRASSINOSTEROID INSENSITIVE 1-like protein 1) Length = 1166 Score = 74.7 bits (182), Expect = 2e-13 Identities = 49/150 (32%), Positives = 78/150 (52%), Gaps = 7/150 (4%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTHATTRPM-GTSGYLDPEYYATSHLSEKSDVYSFG 390 +LL D EAR+SDFG+ R S+ + TH + + GT GY+ PEYY + + K DVYS+G Sbjct: 993 VLLDEDFEARVSDFGMARLVSA-LDTHLSVSTLAGTPGYVPPEYYQSFRCTAKGDVYSYG 1051 Query: 389 ILLLVLITAQPVIVTANNAKRENISLWVRSRLLEG------DIESLTDLRIRGHYDVNSV 228 ++LL L++ + I + N+ W + E D E +TD G ++ Sbjct: 1052 VILLELLSGKKPIDPGEFGEDNNLVGWAKQLYREKRGAEILDPELVTDK--SGDVELFHY 1109 Query: 227 WKVAEMALHCTEHKRQDRPTMMEVVEGLKE 138 K+A C + + RPTM++++ KE Sbjct: 1110 LKIAS---QCLDDRPFKRPTMIQLMAMFKE 1136
>PSKR_DAUCA (Q8LPB4) Phytosulfokine receptor precursor (EC 2.7.11.1)| (Phytosulfokine LRR receptor kinase) Length = 1021 Score = 72.4 bits (176), Expect = 8e-13 Identities = 51/143 (35%), Positives = 70/143 (48%), Gaps = 1/143 (0%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTHATTRPMGTSGYLDPEYYATSHLSEKSDVYSFGI 387 ILL+ A ++DFGL R TH TT +GT GY+ PEY S + K DVYSFG+ Sbjct: 875 ILLSDTFVAHLADFGLARLILP-YDTHVTTDLVGTLGYIPPEYGQASVATYKGDVYSFGV 933 Query: 386 LLLVLITA-QPVIVTANNAKRENISLWVRSRLLEGDIESLTDLRIRGHYDVNSVWKVAEM 210 +LL L+T +P+ V R+ IS WV E + D I + V E+ Sbjct: 934 VLLELLTGRRPMDVCKPRGSRDLIS-WVLQMKTEKRESEIFDPFIYDKDHAEEMLLVLEI 992 Query: 209 ALHCTEHKRQDRPTMMEVVEGLK 141 A C + RPT ++V L+ Sbjct: 993 ACRCLGENPKTRPTTQQLVSWLE 1015
>IRAK4_MOUSE (Q8R4K2) Interleukin-1 receptor-associated kinase 4 (EC 2.7.11.1)| (IRAK-4) Length = 459 Score = 70.5 bits (171), Expect = 3e-12 Identities = 50/145 (34%), Positives = 76/145 (52%), Gaps = 2/145 (1%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTHATTRPMGTSGYLDPEYYATSHLSEKSDVYSFGI 387 ILL D A+ISDFGL RA + T T+R +GT+ Y+ PE ++ KSD+YSFG+ Sbjct: 317 ILLDKDFTAKISDFGLARASARLAQTVMTSRIVGTTAYMAPE-ALRGEITPKSDIYSFGV 375 Query: 386 LLLVLITAQPVIVTANNAKRENISLWVRSRL--LEGDIESLTDLRIRGHYDVNSVWKVAE 213 +LL LIT + + + + L ++ + E IE TD ++ D SV + Sbjct: 376 VLLELITG---LAAVDENREPQLLLDIKEEIEDEEKTIEDYTDEKM-SDADPASVEAMYS 431 Query: 212 MALHCTEHKRQDRPTMMEVVEGLKE 138 A C K+ RP + +V + L+E Sbjct: 432 AASQCLHEKKNRRPDIAKVQQLLQE 456
>KPRO_MAIZE (P17801) Putative receptor protein kinase ZmPK1 precursor (EC| 2.7.11.1) Length = 817 Score = 70.1 bits (170), Expect = 4e-12 Identities = 48/149 (32%), Positives = 72/149 (48%), Gaps = 8/149 (5%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTHATTRPMGTSGYLDPEYYATSHLSEKSDVYSFGI 387 ILL E +I+DFGL + + ST + GT GY+ PE+ ++ ++ K DVYS+G+ Sbjct: 664 ILLDQAFEPKITDFGLVKLLNRGGSTQNVSHVRGTLGYIAPEWVSSLPITAKVDVYSYGV 723 Query: 386 LLLVLITAQPVIVTANNAKRENISLWVRSRLLEGDIESLTDLRIRGHYD------VNSVW 225 +LL L+T V + L R+L +E I G+ D VN V Sbjct: 724 VLLELLTGTRVSELVGGTDEVHSMLRKLVRMLSAKLEGEEQSWIDGYLDSKLNRPVNYVQ 783 Query: 224 --KVAEMALHCTEHKRQDRPTMMEVVEGL 144 + ++A+ C E R RPTM V+ L Sbjct: 784 ARTLIKLAVSCLEEDRSKRPTMEHAVQTL 812
>SRK6_BRAOE (Q09092) Putative serine/threonine-protein kinase receptor precursor| (EC 2.7.11.1) (S-receptor kinase) (SRK) Length = 849 Score = 69.7 bits (169), Expect = 5e-12 Identities = 45/145 (31%), Positives = 71/145 (48%), Gaps = 7/145 (4%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTHATTRPMGTSGYLDPEYYATSHLSEKSDVYSFGI 387 ILL ++ +ISDFG+ R F + + T + +GT GY+ PEY SEKSDV+SFG+ Sbjct: 659 ILLDKNMIPKISDFGMARIFERDETEANTMKVVGTYGYMSPEYAMYGIFSEKSDVFSFGV 718 Query: 386 LLLVLITAQPVIVTANNAKRENISLWVRSRLLEGDIESLTDLRI-------RGHYDVNSV 228 ++L +++ + N ++ +V SR EG + D I + V Sbjct: 719 IVLEIVSGKKNRGFYNLDYENDLLSYVWSRWKEGRALEIVDPVIVDSLSSQPSIFQPQEV 778 Query: 227 WKVAEMALHCTEHKRQDRPTMMEVV 153 K ++ L C + + RP M VV Sbjct: 779 LKCIQIGLLCVQELAEHRPAMSSVV 803
>IRAK4_HUMAN (Q9NWZ3) Interleukin-1 receptor-associated kinase 4 (EC 2.7.11.1)| (IRAK-4) (NY-REN-64 antigen) Length = 460 Score = 68.9 bits (167), Expect = 9e-12 Identities = 48/145 (33%), Positives = 75/145 (51%), Gaps = 2/145 (1%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTHATTRPMGTSGYLDPEYYATSHLSEKSDVYSFGI 387 ILL A+ISDFGL RA T T+R +GT+ Y+ PE ++ KSD+YSFG+ Sbjct: 317 ILLDEAFTAKISDFGLARASEKFAQTVMTSRIVGTTAYMAPE-ALRGEITPKSDIYSFGV 375 Query: 386 LLLVLITAQPVIVTANNAKRENISLWVRSRL--LEGDIESLTDLRIRGHYDVNSVWKVAE 213 +LL +IT P + + + + L ++ + E IE D ++ D SV + Sbjct: 376 VLLEIITGLPAV---DEHREPQLLLDIKEEIEDEEKTIEDYIDKKM-NDADSTSVEAMYS 431 Query: 212 MALHCTEHKRQDRPTMMEVVEGLKE 138 +A C K+ RP + +V + L+E Sbjct: 432 VASQCLHEKKNKRPDIKKVQQLLQE 456
>KPEL_DROME (Q05652) Probable serine/threonine-protein kinase pelle (EC| 2.7.11.1) Length = 501 Score = 60.5 bits (145), Expect = 3e-09 Identities = 46/142 (32%), Positives = 68/142 (47%), Gaps = 3/142 (2%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTHA-TTRPMGTSGYLDPEYYATSHLSEKSDVYSFG 390 ILL L+ +I DFGL R + + GT YL PE+ LS DVYSFG Sbjct: 352 ILLDQCLQPKIGDFGLVREGPKSLDAVVEVNKVFGTKIYLPPEFRNFRQLSTGVDVYSFG 411 Query: 389 ILLLVLITAQPVI-VTANNAKRENISLWVRSRLLEGDIESL-TDLRIRGHYDVNSVWKVA 216 I+LL + T + V N ++N+ +V+ + + +E L L +++ Sbjct: 412 IVLLEVFTGRQVTDRVPENETKKNLLDYVKQQWRQNRMELLEKHLAAPMGKELDMCMCAI 471 Query: 215 EMALHCTEHKRQDRPTMMEVVE 150 E LHCT QDRP+M V++ Sbjct: 472 EAGLHCTALDPQDRPSMNAVLK 493
>KYK1_DICDI (P18160) Non-receptor tyrosine kinase spore lysis A (EC 2.7.10.2)| (Tyrosine-protein kinase 1) Length = 1584 Score = 55.1 bits (131), Expect = 1e-07 Identities = 45/150 (30%), Positives = 70/150 (46%) Frame = -2 Query: 551 DLEARISDFGLTRAFSSEMSTHATTRPMGTSGYLDPEYYATSHLSEKSDVYSFGILLLVL 372 D++ +ISDFGL+R + S T+ +G Y+ PE + SEKSDVYS+G++L L Sbjct: 1441 DIKCKISDFGLSRLKKEQASQ--MTQSVGCIPYMAPEVFKGDSNSEKSDVYSYGMVLFEL 1498 Query: 371 ITAQPVIVTANNAKRENISLWVRSRLLEGDIESLTDLRIRGHYDVNSVWKVAEMALHCTE 192 +T+ K +++ + R I T +S WK E+ C + Sbjct: 1499 LTSDEPQQDMKPMKMAHLAAYESYR---PPIPLTT----------SSKWK--EILTQCWD 1543 Query: 191 HKRQDRPTMMEVVEGLKEGLQLENSSRSSV 102 RPT +++ LKE SS +SV Sbjct: 1544 SNPDSRPTFKQIIVHLKEMEDQGVSSFASV 1573
>RIPK3_HUMAN (Q9Y572) Receptor-interacting serine/threonine-protein kinase 3 (EC| 2.7.11.1) (RIP-like protein kinase 3) (Receptor-interacting protein 3) (RIP-3) Length = 518 Score = 53.5 bits (127), Expect = 4e-07 Identities = 45/164 (27%), Positives = 75/164 (45%), Gaps = 3/164 (1%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTHATTRPMGTSGYLDPEYYATSH--LSEKSDVYSF 393 +L +L +++DFGL+ S + P GT GYL PE + + S SDVYSF Sbjct: 148 VLPDPELHVKLADFGLSTFQGGSQSGTGSGEPGGTLGYLAPELFVNVNRKASTASDVYSF 207 Query: 392 GILLLVLITAQPVIVTANNAKRENISLWVRSRLLEGDIESLTDLRIRGHYDVNSVWKVAE 213 GIL+ ++ + V + SL + + SL +L G + + + E Sbjct: 208 GILMWAVLAGREVELPTEP------SLVYEAVCNRQNRPSLAELPQAGP-ETPGLEGLKE 260 Query: 212 MALHCTEHKRQDRPTMMEVVEGLKEGLQL-ENSSRSSVETGRQF 84 + C + +DRP+ E + E Q+ EN+ ++V T + F Sbjct: 261 LMQLCWSSEPKDRPSFQECLPKTDEVFQMVENNMNAAVSTVKDF 304
>PKNB_MYCLE (P54744) Probable serine/threonine-protein kinase pknB (EC| 2.7.11.1) Length = 622 Score = 52.4 bits (124), Expect = 9e-07 Identities = 24/73 (32%), Positives = 40/73 (54%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTHATTRPMGTSGYLDPEYYATSHLSEKSDVYSFGI 387 I+++A ++ DFG+ RA + S T +GT+ YL PE + +SDVYS G Sbjct: 144 IMISATNAVKVMDFGIARAIADSTSVTQTAAVIGTAQYLSPEQARGDSVDARSDVYSLGC 203 Query: 386 LLLVLITAQPVIV 348 +L ++T +P + Sbjct: 204 VLYEILTGEPPFI 216
>PKNX_STRCO (Q9XA16) Probable serine/threonine-protein kinase SCO3848 (EC| 2.7.11.1) Length = 673 Score = 50.8 bits (120), Expect = 3e-06 Identities = 27/74 (36%), Positives = 42/74 (56%), Gaps = 1/74 (1%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFS-SEMSTHATTRPMGTSGYLDPEYYATSHLSEKSDVYSFG 390 ++LT + + ++ DFG+ RA S M+ T +GT+ YL PE + +SD+YS G Sbjct: 144 VMLTRNGQVKVMDFGIARAMGDSGMTMTQTAAVIGTAQYLSPEQAKGEQVDARSDLYSTG 203 Query: 389 ILLLVLITAQPVIV 348 LL L+T +P V Sbjct: 204 CLLYELLTVRPPFV 217
>RIPK3_MOUSE (Q9QZL0) Receptor-interacting serine/threonine-protein kinase 3 (EC| 2.7.11.1) (RIP-like protein kinase 3) (Receptor-interacting protein 3) (RIP-3) (mRIP3) Length = 486 Score = 50.1 bits (118), Expect = 4e-06 Identities = 46/146 (31%), Positives = 72/146 (49%), Gaps = 10/146 (6%) Frame = -2 Query: 566 ILLTADLEARISDFGLTR----AFSSEMSTHATTRPMGTSGYLDPEYYATSHL--SEKSD 405 ILL +L A+++DFGL+ + S S + GT YLDPE +L S+ SD Sbjct: 149 ILLDPELHAKLADFGLSTFQGGSQSGSGSGSGSRDSGGTLAYLDPELLFKVNLKASKASD 208 Query: 404 VYSFGILL-LVLITAQPVIVTANNAKRENISLWVRSRLLEGDIES---LTDLRIRGHYDV 237 VYSFGIL+ VL + +V + RE + D +S LT+L G + Sbjct: 209 VYSFGILVWAVLAGREAELVDKTSLIRETVC----------DRQSRPPLTELP-PGSPET 257 Query: 236 NSVWKVAEMALHCTEHKRQDRPTMME 159 + K+ E+ +HC + ++RP+ + Sbjct: 258 PGLEKLKELMIHCWGSQSENRPSFQD 283
>PKNL_MYCTU (O53510) Probable serine/threonine-protein kinase pknL (EC| 2.7.11.1) Length = 399 Score = 49.7 bits (117), Expect = 6e-06 Identities = 26/67 (38%), Positives = 42/67 (62%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTHATTRPMGTSGYLDPEYYATSHLSEKSDVYSFGI 387 IL++ D + +++DFGL RA ++ T +T +GT+ YL PE + +SDVYS G+ Sbjct: 148 ILISDDGDVKLADFGLVRAVAAASIT-STGVILGTAAYLSPEQVRDGNADPRSDVYSVGV 206 Query: 386 LLLVLIT 366 L+ L+T Sbjct: 207 LVYELLT 213
>PKNL_MYCBO (Q7TYY6) Probable serine/threonine-protein kinase pknL (EC| 2.7.11.1) Length = 399 Score = 49.7 bits (117), Expect = 6e-06 Identities = 26/67 (38%), Positives = 42/67 (62%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTHATTRPMGTSGYLDPEYYATSHLSEKSDVYSFGI 387 IL++ D + +++DFGL RA ++ T +T +GT+ YL PE + +SDVYS G+ Sbjct: 148 ILISDDGDVKLADFGLVRAVAAASIT-STGVILGTAAYLSPEQVRDGNADPRSDVYSVGV 206 Query: 386 LLLVLIT 366 L+ L+T Sbjct: 207 LVYELLT 213
>TMKL1_ARATH (P33543) Putative kinase-like protein TMKL1 precursor| Length = 674 Score = 49.7 bits (117), Expect = 6e-06 Identities = 45/161 (27%), Positives = 76/161 (47%), Gaps = 12/161 (7%) Frame = -2 Query: 542 ARISDFGLTRAFSSEMSTHATTRPMGTSGYLDPEYYATSHLSEKSDVYSFGILLL-VLIT 366 AR+++FGL + ++ ++ + GY PE + + +SDVY+FGILLL +L+ Sbjct: 514 ARLTEFGLDKIMVQAVADEIVSQAK-SDGYKAPELHKMKKCNPRSDVYAFGILLLEILMG 572 Query: 365 AQPVIVTANNAKRENISLWVRSRLLEGDIESLTDLR----IRGHYDVNSVWKVAEMALHC 198 +P N + ++ V++ +LE + DL IR + V ++A+ C Sbjct: 573 KKPGKSGRNGNEFVDLPSLVKAAVLEETTMEVFDLEAMKGIRSPMEEGLV-HALKLAMGC 631 Query: 197 TEHKRQDRPTMMEVVEGLKE-------GLQLENSSRSSVET 96 RP+M EVV+ L+E L +RS ET Sbjct: 632 CAPVTTVRPSMEEVVKQLEENRPRNRSALYSPTETRSDAET 672
>RMIL_AVII1 (P10533) Serine/threonine-protein kinase transforming protein Rmil| (EC 2.7.11.1) Length = 367 Score = 48.1 bits (113), Expect = 2e-05 Identities = 39/145 (26%), Positives = 61/145 (42%), Gaps = 3/145 (2%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTHATTRPMGTSGYLDPEYYATSH---LSEKSDVYS 396 I L DL +I DFGL S +H + G+ ++ PE S +SDVY+ Sbjct: 192 IFLHEDLTVKIGDFGLATVKSRWSGSHQFEQLSGSILWMAPEVIRMQDKNPYSFQSDVYA 251 Query: 395 FGILLLVLITAQPVIVTANNAKRENISLWVRSRLLEGDIESLTDLRIRGHYDVNSVWKVA 216 FGI+L L+T Q NN R+ I V L D+ + N + Sbjct: 252 FGIVLYELMTGQLPYSNINN--RDQIIFMVGRGYLSPDLSKVRS---------NCPKAMK 300 Query: 215 EMALHCTEHKRQDRPTMMEVVEGLK 141 + C + KR +RP +++ ++ Sbjct: 301 RLMAECLKKKRDERPLFPQILASIE 325
>BRAF1_COTJA (P34908) B-Raf proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (RMIL serine/threonine-protein kinase) (c-RMIL) Length = 807 Score = 48.1 bits (113), Expect = 2e-05 Identities = 39/145 (26%), Positives = 61/145 (42%), Gaps = 3/145 (2%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTHATTRPMGTSGYLDPEYYATSH---LSEKSDVYS 396 I L DL +I DFGL S +H + G+ ++ PE S +SDVY+ Sbjct: 622 IFLHEDLTVKIGDFGLATVKSRWSGSHQFEQLSGSILWMAPEVIRMQDKNPYSFQSDVYA 681 Query: 395 FGILLLVLITAQPVIVTANNAKRENISLWVRSRLLEGDIESLTDLRIRGHYDVNSVWKVA 216 FGI+L L+T Q NN R+ I V L D+ + N + Sbjct: 682 FGIVLYELMTGQLPYSNINN--RDQIIFMVGRGYLSPDLSKVRS---------NCPKAMK 730 Query: 215 EMALHCTEHKRQDRPTMMEVVEGLK 141 + C + KR +RP +++ ++ Sbjct: 731 RLMAECLKKKRDERPLFPQILASIE 755
>BRAF1_CHICK (Q04982) B-Raf proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (Rmil serine/threonine-protein kinase) (c-Rmil) Length = 806 Score = 48.1 bits (113), Expect = 2e-05 Identities = 39/145 (26%), Positives = 61/145 (42%), Gaps = 3/145 (2%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTHATTRPMGTSGYLDPEYYATSH---LSEKSDVYS 396 I L DL +I DFGL S +H + G+ ++ PE S +SDVY+ Sbjct: 622 IFLHEDLTVKIGDFGLATVKSRWSGSHQFEQLSGSILWMAPEVIRMQDKNPYSFQSDVYA 681 Query: 395 FGILLLVLITAQPVIVTANNAKRENISLWVRSRLLEGDIESLTDLRIRGHYDVNSVWKVA 216 FGI+L L+T Q NN R+ I V L D+ + N + Sbjct: 682 FGIVLYELMTGQLPYSNINN--RDQIIFMVGRGYLSPDLSKVRS---------NCPKAMK 730 Query: 215 EMALHCTEHKRQDRPTMMEVVEGLK 141 + C + KR +RP +++ ++ Sbjct: 731 RLMAECLKKKRDERPLFPQILASIE 755
>PKNB_MYCTU (P0A5S4) Probable serine/threonine-protein kinase pknB (EC| 2.7.11.1) Length = 626 Score = 48.1 bits (113), Expect = 2e-05 Identities = 31/107 (28%), Positives = 53/107 (49%), Gaps = 8/107 (7%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFS-SEMSTHATTRPMGTSGYLDPEYYATSHLSEKSDVYSFG 390 I+++A ++ DFG+ RA + S S T +GT+ YL PE + +SDVYS G Sbjct: 144 IMISATNAVKVMDFGIARAIADSGNSVTQTAAVIGTAQYLSPEQARGDSVDARSDVYSLG 203 Query: 389 ILLLVLITAQ-------PVIVTANNAKRENISLWVRSRLLEGDIESL 270 +L ++T + PV V + + + I R L D++++ Sbjct: 204 CVLYEVLTGEPPFTGDSPVSVAYQHVREDPIPPSARHEGLSADLDAV 250
>PKNB_MYCBO (P0A5S5) Probable serine/threonine-protein kinase pknB (EC| 2.7.11.1) Length = 626 Score = 48.1 bits (113), Expect = 2e-05 Identities = 31/107 (28%), Positives = 53/107 (49%), Gaps = 8/107 (7%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFS-SEMSTHATTRPMGTSGYLDPEYYATSHLSEKSDVYSFG 390 I+++A ++ DFG+ RA + S S T +GT+ YL PE + +SDVYS G Sbjct: 144 IMISATNAVKVMDFGIARAIADSGNSVTQTAAVIGTAQYLSPEQARGDSVDARSDVYSLG 203 Query: 389 ILLLVLITAQ-------PVIVTANNAKRENISLWVRSRLLEGDIESL 270 +L ++T + PV V + + + I R L D++++ Sbjct: 204 CVLYEVLTGEPPFTGDSPVSVAYQHVREDPIPPSARHEGLSADLDAV 250
>BRAF1_MOUSE (P28028) B-Raf proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (Fragment) Length = 328 Score = 48.1 bits (113), Expect = 2e-05 Identities = 39/145 (26%), Positives = 61/145 (42%), Gaps = 3/145 (2%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTHATTRPMGTSGYLDPEYYATSH---LSEKSDVYS 396 I L DL +I DFGL S +H + G+ ++ PE S +SDVY+ Sbjct: 144 IFLHEDLTVKIGDFGLATVKSRWSGSHQFEQLSGSILWMAPEVIRMQDKNPYSFQSDVYA 203 Query: 395 FGILLLVLITAQPVIVTANNAKRENISLWVRSRLLEGDIESLTDLRIRGHYDVNSVWKVA 216 FGI+L L+T Q NN R+ I V L D+ + N + Sbjct: 204 FGIVLYELMTGQLPYSNINN--RDQIIFMVGRGYLSPDLSKVRS---------NCPKAMK 252 Query: 215 EMALHCTEHKRQDRPTMMEVVEGLK 141 + C + KR +RP +++ ++ Sbjct: 253 RLMAECLKKKRDERPLFPQILASIE 277
>RMIL_AVEVR (P27966) Serine/threonine-protein kinase transforming protein Rmil| (EC 2.7.11.1) Length = 450 Score = 48.1 bits (113), Expect = 2e-05 Identities = 39/145 (26%), Positives = 61/145 (42%), Gaps = 3/145 (2%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTHATTRPMGTSGYLDPEYYATSH---LSEKSDVYS 396 I L DL +I DFGL S +H + G+ ++ PE S +SDVY+ Sbjct: 208 IFLHEDLTVKIGDFGLATVKSRWSGSHQFEQLSGSILWMAPEVIRMQDKNPYSFQSDVYA 267 Query: 395 FGILLLVLITAQPVIVTANNAKRENISLWVRSRLLEGDIESLTDLRIRGHYDVNSVWKVA 216 FGI+L L+T Q NN R+ I V L D+ + N + Sbjct: 268 FGIVLYELMTGQLPYSNINN--RDQIIFMVGRGYLSPDLSKVRS---------NCPKAMK 316 Query: 215 EMALHCTEHKRQDRPTMMEVVEGLK 141 + C + KR +RP +++ ++ Sbjct: 317 RLMAECLKKKRDERPLFPQILASIE 341
>BRAF1_HUMAN (P15056) B-Raf proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (p94) (v-Raf murine sarcoma viral oncogene homolog B1) Length = 766 Score = 48.1 bits (113), Expect = 2e-05 Identities = 39/145 (26%), Positives = 61/145 (42%), Gaps = 3/145 (2%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTHATTRPMGTSGYLDPEYYATSH---LSEKSDVYS 396 I L DL +I DFGL S +H + G+ ++ PE S +SDVY+ Sbjct: 582 IFLHEDLTVKIGDFGLATVKSRWSGSHQFEQLSGSILWMAPEVIRMQDKNPYSFQSDVYA 641 Query: 395 FGILLLVLITAQPVIVTANNAKRENISLWVRSRLLEGDIESLTDLRIRGHYDVNSVWKVA 216 FGI+L L+T Q NN R+ I V L D+ + N + Sbjct: 642 FGIVLYELMTGQLPYSNINN--RDQIIFMVGRGYLSPDLSKVRS---------NCPKAMK 690 Query: 215 EMALHCTEHKRQDRPTMMEVVEGLK 141 + C + KR +RP +++ ++ Sbjct: 691 RLMAECLKKKRDERPLFPQILASIE 715
>CCAMK_PEA (Q6RET6) Calcium and calcium/calmodulin-dependent| serine/threonine-protein kinase (EC 2.7.11.17) (PsCCaMK) (Ps-SYM9) (Fragment) Length = 527 Score = 47.4 bits (111), Expect = 3e-05 Identities = 24/80 (30%), Positives = 43/80 (53%) Frame = -2 Query: 551 DLEARISDFGLTRAFSSEMSTHATTRPMGTSGYLDPEYYATSHLSEKSDVYSFGILLLVL 372 D +I DFGL+ S E T G+ Y+ PE + ++ KSD++S G++L +L Sbjct: 193 DSSLKIMDFGLS---SVEEFTDPVVGLFGSIDYVSPEALSQGKITTKSDMWSLGVILYIL 249 Query: 371 ITAQPVIVTANNAKRENISL 312 ++ P + NN +++ + L Sbjct: 250 LSGYPPFIAQNNRQKQQMIL 269
>PKNB_LACLA (Q9CEF5) Probable serine/threonine-protein kinase pknB (EC| 2.7.11.1) Length = 627 Score = 47.0 bits (110), Expect = 4e-05 Identities = 24/69 (34%), Positives = 41/69 (59%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTHATTRPMGTSGYLDPEYYATSHLSEKSDVYSFGI 387 +L+++ +++DFG+ +A S E S T G+ YL PE S+ + +SD+Y+ GI Sbjct: 142 VLVSSSGTVKVTDFGIAKALS-ETSLTQTNTMFGSVHYLSPEQARGSNATVQSDIYAIGI 200 Query: 386 LLLVLITAQ 360 +L L+T Q Sbjct: 201 ILFELLTGQ 209
>CCAMK_MEDTR (Q6RET7) Calcium and calcium/calmodulin-dependent| serine/threonine-protein kinase DMI-3 (EC 2.7.11.17) (Does not make infections protein 3) (CCaMK DMI3) (MtCCaMK) Length = 523 Score = 46.2 bits (108), Expect = 6e-05 Identities = 23/78 (29%), Positives = 42/78 (53%) Frame = -2 Query: 551 DLEARISDFGLTRAFSSEMSTHATTRPMGTSGYLDPEYYATSHLSEKSDVYSFGILLLVL 372 D +I DFGL+ S E T G+ Y+ PE + ++ KSD++S G++L +L Sbjct: 185 DSPLKIMDFGLS---SVEEFTDPVVGLFGSIDYVSPEALSQGKITTKSDMWSLGVILYIL 241 Query: 371 ITAQPVIVTANNAKRENI 318 ++ P + NN +++ + Sbjct: 242 LSGYPPFIAQNNRQKQQM 259
>IRAK3_MOUSE (Q8K4B2) Interleukin-1 receptor-associated kinase 3 (EC 2.7.11.1)| (IRAK-3) (IL-1 receptor-associated kinase M) (IRAK-M) Length = 609 Score = 46.2 bits (108), Expect = 6e-05 Identities = 43/149 (28%), Positives = 71/149 (47%), Gaps = 7/149 (4%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTHATTRPMGTSG-----YLDPEYYATSHLSEKSDV 402 ILL L+ +++DF F + ++T M G Y+ EY LS K+DV Sbjct: 312 ILLDDQLQPKLTDFAAAH-FRPNLEQQSSTINMTGGGRKHLWYMPEEYIRQGRLSVKTDV 370 Query: 401 YSFGILLLVLITAQPVIV--TANNAKRENISLWVRSRLLEGDIESLTDLRIRGHYDVNSV 228 YSFGI+++ ++T V++ + R+ + + R L+ + S D +I N Sbjct: 371 YSFGIVIMEVLTGCKVVLDDPKHVQLRDLLMELMEKRGLDSCL-SFLDRKI-PPCPRNFS 428 Query: 227 WKVAEMALHCTEHKRQDRPTMMEVVEGLK 141 K+ +A C K + RPTM EV+ L+ Sbjct: 429 AKLFSLAGRCVATKAKLRPTMDEVLSSLE 457
>PKN1_THETN (Q8R9T6) Probable serine/threonine-protein kinase Sps1 (EC| 2.7.11.1) Length = 625 Score = 46.2 bits (108), Expect = 6e-05 Identities = 24/69 (34%), Positives = 42/69 (60%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTHATTRPMGTSGYLDPEYYATSHLSEKSDVYSFGI 387 IL+T + +++DFG+ RA + T+ T +GT+ Y PE S + E++D+YS GI Sbjct: 140 ILVTDEDVVKVTDFGIARAANGATITY-TGDVIGTAYYFSPEQAKGSIVDERTDIYSLGI 198 Query: 386 LLLVLITAQ 360 +L ++T + Sbjct: 199 VLFEMLTGK 207
>PKN2_BACSU (O34507) Probable serine/threonine-protein kinase yloP (EC| 2.7.11.1) Length = 648 Score = 45.8 bits (107), Expect = 8e-05 Identities = 23/60 (38%), Positives = 36/60 (60%) Frame = -2 Query: 539 RISDFGLTRAFSSEMSTHATTRPMGTSGYLDPEYYATSHLSEKSDVYSFGILLLVLITAQ 360 +++DFG+ A SS TH T +G+ YL PE ++KSD+Y+ GI+L L+T + Sbjct: 149 KVTDFGIATALSSTTITH-TNSVLGSVHYLSPEQARGGLATKKSDIYALGIVLFELLTGR 207
>KCCS_MALDO (Q07250) Calcium/calmodulin-dependent serine/threonine-protein| kinase (EC 2.7.11.17) Length = 415 Score = 45.4 bits (106), Expect = 1e-04 Identities = 22/80 (27%), Positives = 43/80 (53%) Frame = -2 Query: 557 TADLEARISDFGLTRAFSSEMSTHATTRPMGTSGYLDPEYYATSHLSEKSDVYSFGILLL 378 T D +I DFGL+ S E T G+ Y+ PE + ++ KSD+++ G++L Sbjct: 185 TVDSPLKIMDFGLS---SVEEFTDPVVGLFGSIDYVSPEALSQGQVTSKSDMWALGVILY 241 Query: 377 VLITAQPVIVTANNAKRENI 318 +L++ P + +N +++ + Sbjct: 242 ILLSGYPPFIAQSNRQKQQM 261
>PKN5_MYXXA (P54737) Serine/threonine-protein kinase pkn5 (EC 2.7.11.1)| Length = 380 Score = 45.4 bits (106), Expect = 1e-04 Identities = 38/144 (26%), Positives = 68/144 (47%), Gaps = 1/144 (0%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTHATTRPMGTSGYLDPEYYATSHLSEKSDVYSFGI 387 I++ D + R+ DFGL + + + + + +GT Y+ PE L ++D+YS G+ Sbjct: 250 IMVDDDRQVRLMDFGLAKFLADDAAITEAGKLVGTYRYMAPEQILGEPLDGRADLYSLGV 309 Query: 386 LLLVLITAQPVIVTANNAKRENISLWVRSRLLEGDIESLTDLRIRGHYDVNSVWKVAEMA 207 +L L++ +P +AK + LW ++LE + + L + G ++A +A Sbjct: 310 ILYELLSGRPPF----DAKTPH-ELW--RQVLETEPPPVLALNLHGDP------QLARVA 356 Query: 206 LHCTEHKRQDR-PTMMEVVEGLKE 138 + DR T EV E L E Sbjct: 357 HRLIRKEPDDRFQTAEEVYEALSE 380
>PKN2_CLOAB (Q97IC2) Probable serine/threonine protein kinase CAC1728 (EC| 2.7.11.1) Length = 657 Score = 45.1 bits (105), Expect = 1e-04 Identities = 23/69 (33%), Positives = 43/69 (62%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTHATTRPMGTSGYLDPEYYATSHLSEKSDVYSFGI 387 I++T D +++DFG+ +A S+E + T + +G++ YL PE + ++D+YSFGI Sbjct: 139 IMVTDDDIIKVTDFGIAKA-SNESTITTTNKVVGSAHYLSPEQAQGIPVDCRTDIYSFGI 197 Query: 386 LLLVLITAQ 360 +L + T + Sbjct: 198 VLYEMATGK 206
>CDS1_SCHPO (Q09170) Serine/threonine-protein kinase cds1 (EC 2.7.11.1)| (Checkpoint kinase cds1) Length = 460 Score = 45.1 bits (105), Expect = 1e-04 Identities = 28/85 (32%), Positives = 45/85 (52%), Gaps = 6/85 (7%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTHATTRPMGTSGYLDPEYYATSHLS------EKSD 405 IL+T D +ISDFGL + + T GT GYL PE + +++ +K D Sbjct: 300 ILITNDFHLKISDFGLAKVIHGTGTFLETF--CGTMGYLAPEVLKSKNVNLDGGYDDKVD 357 Query: 404 VYSFGILLLVLITAQPVIVTANNAK 330 ++S G +L V++TA +++ AK Sbjct: 358 IWSLGCVLYVMLTASIPFASSSQAK 382
>PK1_STRTO (Q9KIG4) Serine/threonine-protein kinase PK-1 (EC 2.7.11.1)| (stoPK-1) Length = 641 Score = 45.1 bits (105), Expect = 1e-04 Identities = 25/69 (36%), Positives = 37/69 (53%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTHATTRPMGTSGYLDPEYYATSHLSEKSDVYSFGI 387 +L+ D +++DFGL RA S +T T +GT YL PE + DVY+ GI Sbjct: 147 VLIGDDGRVKVADFGLVRAVDSVTNTTGTV--LGTVSYLAPEQIEHGTADPRVDVYACGI 204 Query: 386 LLLVLITAQ 360 LL ++T + Sbjct: 205 LLYEMLTGE 213
>M3K10_HUMAN (Q02779) Mitogen-activated protein kinase kinase kinase 10 (EC| 2.7.11.25) (Mixed lineage kinase 2) (Protein kinase MST) Length = 954 Score = 44.7 bits (104), Expect = 2e-04 Identities = 27/67 (40%), Positives = 38/67 (56%), Gaps = 2/67 (2%) Frame = -2 Query: 554 ADLEARISDFGLTRAFSSEMSTHATTR--PMGTSGYLDPEYYATSHLSEKSDVYSFGILL 381 AD +I+DFGL R + H TT+ GT ++ PE S S+ SDV+SFG+LL Sbjct: 240 ADTVLKITDFGLAREW------HKTTKMSAAGTYAWMAPEVIRLSLFSKSSDVWSFGVLL 293 Query: 380 LVLITAQ 360 L+T + Sbjct: 294 WELLTGE 300
>PKN2_CLOPE (Q8XJL8) Probable serine/threonine protein kinase CPE1738 (EC| 2.7.11.1) Length = 685 Score = 44.7 bits (104), Expect = 2e-04 Identities = 21/67 (31%), Positives = 39/67 (58%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTHATTRPMGTSGYLDPEYYATSHLSEKSDVYSFGI 387 IL+T + +++DFG+ ++ S H T MG++ Y PE ++ ++D+YS GI Sbjct: 139 ILVTEEGVVKVTDFGIAKSMDSSTIAH-TNSVMGSAHYFSPEQAKGTYTDYRTDLYSLGI 197 Query: 386 LLLVLIT 366 +L ++T Sbjct: 198 VLYEMVT 204
>KSG1_SCHPO (Q12701) Serine/threonine-protein kinase ksg1 (EC 2.7.11.1)| Length = 592 Score = 44.3 bits (103), Expect = 2e-04 Identities = 25/88 (28%), Positives = 43/88 (48%), Gaps = 12/88 (13%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSS-----EMSTHATTRP-------MGTSGYLDPEYYATSH 423 ILL ++ +I+DFG + +S E TH +P +GT+ Y+ PE + Sbjct: 229 ILLDDNMRTKITDFGSAKILNSSHGSHEEDTHHADKPQAHSRSFVGTARYVSPEVLSDKI 288 Query: 422 LSEKSDVYSFGILLLVLITAQPVIVTAN 339 SD+++FG +L ++ +P V N Sbjct: 289 AGTASDIWAFGCILFQMLAGKPPFVAGN 316
>ITK_MOUSE (Q03526) Tyrosine-protein kinase ITK/TSK (EC 2.7.10.2)| (T-cell-specific kinase) (IL-2-inducible T-cell kinase) (Kinase EMT) (Kinase TLK) Length = 625 Score = 44.3 bits (103), Expect = 2e-04 Identities = 37/136 (27%), Positives = 62/136 (45%), Gaps = 2/136 (1%) Frame = -2 Query: 539 RISDFGLTRAFSSEMSTHATTRPMGTSGYLDPEYYATSHLSEKSDVYSFGILLLVLITAQ 360 ++SDFG+TR + T +T + PE ++ S S KSDV+SFG+L+ + + Sbjct: 502 KVSDFGMTRFVLDDQYTSSTGTKFPVK-WASPEVFSFSRYSSKSDVWSFGVLMWEVFSEG 560 Query: 359 --PVIVTANNAKRENISLWVRSRLLEGDIESLTDLRIRGHYDVNSVWKVAEMALHCTEHK 186 P +N+ E+IS RL + + S V ++ HC + K Sbjct: 561 KIPYENRSNSEVVEDIS--TGFRLYKPRLASC---------------HVYQIMNHCWKEK 603 Query: 185 RQDRPTMMEVVEGLKE 138 +DRP +++ L E Sbjct: 604 PEDRPPFSQLLSQLAE 619
>PKH1_YEAST (Q03407) Serine/threonine-protein kinase PKH1 (EC 2.7.11.1)| (3-phosphoinositide-dependent protein kinase 1) Length = 766 Score = 43.9 bits (102), Expect = 3e-04 Identities = 22/87 (25%), Positives = 43/87 (49%), Gaps = 11/87 (12%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTHATTRP-----------MGTSGYLDPEYYATSHL 420 ILL +++ +++DFG + E S A +P +GT+ Y+ PE ++ Sbjct: 255 ILLDKNMKVKLTDFGTAKILPEEPSNTADGKPYFDLYAKSKSFVGTAEYVSPELLNDNYT 314 Query: 419 SEKSDVYSFGILLLVLITAQPVIVTAN 339 + D+++FG +L ++ +P AN Sbjct: 315 DSRCDIWAFGCILYQMLAGKPPFKAAN 341
>M3K12_HUMAN (Q12852) Mitogen-activated protein kinase kinase kinase 12 (EC| 2.7.11.25) (Mixed lineage kinase) (Leucine-zipper protein kinase) (ZPK) (Dual leucine zipper bearing kinase) (DLK) (MAPK-upstream kinase) (MUK) Length = 859 Score = 43.5 bits (101), Expect = 4e-04 Identities = 23/69 (33%), Positives = 40/69 (57%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTHATTRPMGTSGYLDPEYYATSHLSEKSDVYSFGI 387 +L+T D +ISDFG ++ S + + + GT ++ PE +SEK D++SFG+ Sbjct: 242 MLITYDDVVKISDFGTSKELSDKSTKMSFA---GTVAWMAPEVIRNEPVSEKVDIWSFGV 298 Query: 386 LLLVLITAQ 360 +L L+T + Sbjct: 299 VLWELLTGE 307
>PKSC_STRCO (Q9S2C0) Serine/threonine protein kinase pksC (EC 2.7.11.1)| Length = 556 Score = 43.5 bits (101), Expect = 4e-04 Identities = 23/70 (32%), Positives = 39/70 (55%), Gaps = 1/70 (1%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTHATT-RPMGTSGYLDPEYYATSHLSEKSDVYSFG 390 +++T ++ DFG+ RA S +++ T +GT YL PE + +SD+YS G Sbjct: 157 VMMTKRGVVKVMDFGIARAMQSGVTSMTQTGMVVGTPQYLSPEQALGRGVDARSDLYSVG 216 Query: 389 ILLLVLITAQ 360 I+L L+T + Sbjct: 217 IMLFQLVTGR 226
>RAF1_CHICK (P05625) RAF proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (RAF-1) (C-RAF) (MIL proto-oncogene serine/threonine-protein kinase) (C-MIL) Length = 647 Score = 43.5 bits (101), Expect = 4e-04 Identities = 42/159 (26%), Positives = 66/159 (41%), Gaps = 6/159 (3%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTHATTRPMGTSGYLDPEYYA---TSHLSEKSDVYS 396 I L L +I DFGL S + +P G+ ++ PE ++ S +SDVYS Sbjct: 474 IFLHEGLTVKIGDFGLATVKSRWSGSQQVEQPTGSILWMAPEVIRMQDSNPFSFQSDVYS 533 Query: 395 FGILLLVLITAQPVIVTANNAKRENISLWVRSRLLEGDIESLTDLRIRGHYDVNSVWKVA 216 +GI+L L+T + NN R+ I V D+ L N + Sbjct: 534 YGIVLYELMTGELPYSHINN--RDQIIFMVGRGYASPDLSKLYK---------NCPKAMK 582 Query: 215 EMALHCTEHKRQDRPTMMEV---VEGLKEGLQLENSSRS 108 + C + R++RP ++ +E L+ L N S S Sbjct: 583 RLVADCLKKVREERPLFPQILSSIELLQHSLPKINRSAS 621
>M3K12_RAT (Q63796) Mitogen-activated protein kinase kinase kinase 12 (EC| 2.7.11.25) (Mixed lineage kinase) (Leucine-zipper protein kinase) (ZPK) (Dual leucine zipper bearing kinase) (DLK) (MAPK-upstream kinase) (MUK) Length = 888 Score = 43.5 bits (101), Expect = 4e-04 Identities = 23/69 (33%), Positives = 40/69 (57%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTHATTRPMGTSGYLDPEYYATSHLSEKSDVYSFGI 387 +L+T D +ISDFG ++ S + + + GT ++ PE +SEK D++SFG+ Sbjct: 275 MLITYDDVVKISDFGTSKELSDKSTKMSFA---GTVAWMAPEVIRNEPVSEKVDIWSFGV 331 Query: 386 LLLVLITAQ 360 +L L+T + Sbjct: 332 VLWELLTGE 340
>M3K12_MOUSE (Q60700) Mitogen-activated protein kinase kinase kinase 12 (EC| 2.7.11.25) (Mixed lineage kinase) (Leucine-zipper protein kinase) (ZPK) (Dual leucine zipper bearing kinase) (DLK) (MAPK-upstream kinase) (MUK) Length = 888 Score = 43.5 bits (101), Expect = 4e-04 Identities = 23/69 (33%), Positives = 40/69 (57%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTHATTRPMGTSGYLDPEYYATSHLSEKSDVYSFGI 387 +L+T D +ISDFG ++ S + + + GT ++ PE +SEK D++SFG+ Sbjct: 275 MLITYDDVVKISDFGTSKELSDKSTKMSFA---GTVAWMAPEVIRNEPVSEKVDIWSFGV 331 Query: 386 LLLVLITAQ 360 +L L+T + Sbjct: 332 VLWELLTGE 340
>YR831_MIMIV (Q7T6Y2) Putative serine/threonine-protein kinase/receptor R831| precursor (EC 2.7.11.1) Length = 1624 Score = 43.5 bits (101), Expect = 4e-04 Identities = 38/141 (26%), Positives = 57/141 (40%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTHATTRPMGTSGYLDPEYYATSHLSEKSDVYSFGI 387 IL+ +I+DFG R + T GT + PE EK+DV+SFG+ Sbjct: 1493 ILVDEHFNVKIADFGFARI----KEDNTTMTRCGTPCWTAPEVIRGEKYCEKADVFSFGV 1548 Query: 386 LLLVLITAQPVIVTANNAKRENISLWVRSRLLEGDIESLTDLRIRGHYDVNSVWKVAEMA 207 ++ ++T + N K V +LEG R + + A++ Sbjct: 1549 VMWEVLTGKEPFAECNFMK-------VSLDILEGG---------RPIIPSDCPHEFAKLI 1592 Query: 206 LHCTEHKRQDRPTMMEVVEGL 144 C K RPTM EVV+ L Sbjct: 1593 KKCWHAKAHKRPTMTEVVQQL 1613 Score = 38.1 bits (87), Expect = 0.017 Identities = 24/71 (33%), Positives = 37/71 (52%), Gaps = 2/71 (2%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTHATTRPMGTSGYLDPEYYATSHLSE--KSDVYSF 393 +LL + ++SDFGLT+ S +GT ++ PE S + +DVYSF Sbjct: 914 LLLDSKWNVKVSDFGLTKVKSELDKKKTNDNIIGTIHWIAPEILNDSTEVDYILADVYSF 973 Query: 392 GILLLVLITAQ 360 GI+L L+T + Sbjct: 974 GIILWELLTRE 984
>MIL_AVIMH (P00531) Serine/threonine-protein kinase transforming protein mil| (EC 2.7.11.1) Length = 380 Score = 43.1 bits (100), Expect = 5e-04 Identities = 36/144 (25%), Positives = 60/144 (41%), Gaps = 3/144 (2%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTHATTRPMGTSGYLDPEYYA---TSHLSEKSDVYS 396 I L L +I DFGL S + +P G+ ++ PE ++ S +SDVYS Sbjct: 207 IFLHGGLTVKIGDFGLATVKSRWSGSQQVEQPTGSILWMAPEVIRMQDSNPFSFQSDVYS 266 Query: 395 FGILLLVLITAQPVIVTANNAKRENISLWVRSRLLEGDIESLTDLRIRGHYDVNSVWKVA 216 +GI+L L+T + NN R+ I V D+ L N + Sbjct: 267 YGIVLYELMTGELPYSHINN--RDQIIFMVGRGYASPDLSKLYK---------NCPKAMK 315 Query: 215 EMALHCTEHKRQDRPTMMEVVEGL 144 + C + R++RP +++ + Sbjct: 316 RLVADCLKKVREERPLFPQILSSI 339
>ITK_HUMAN (Q08881) Tyrosine-protein kinase ITK/TSK (EC 2.7.10.2)| (T-cell-specific kinase) (Tyrosine-protein kinase Lyk) (Kinase EMT) Length = 620 Score = 43.1 bits (100), Expect = 5e-04 Identities = 36/136 (26%), Positives = 61/136 (44%), Gaps = 2/136 (1%) Frame = -2 Query: 539 RISDFGLTRAFSSEMSTHATTRPMGTSGYLDPEYYATSHLSEKSDVYSFGILLLVLITAQ 360 ++SDFG+TR + T +T + PE ++ S S KSDV+SFG+L+ + + Sbjct: 497 KVSDFGMTRFVLDDQYTSSTGTKFPVK-WASPEVFSFSRYSSKSDVWSFGVLMWEVFSEG 555 Query: 359 --PVIVTANNAKRENISLWVRSRLLEGDIESLTDLRIRGHYDVNSVWKVAEMALHCTEHK 186 P +N+ E+IS R L R+ + V ++ HC + + Sbjct: 556 KIPYENRSNSEVVEDISTGFR----------LYKPRLASTH-------VYQIMNHCWKER 598 Query: 185 RQDRPTMMEVVEGLKE 138 +DRP ++ L E Sbjct: 599 PEDRPAFSRLLRQLAE 614
>PDPK1_MOUSE (Q9Z2A0) 3-phosphoinositide-dependent protein kinase 1 (EC| 2.7.11.1) (mPDK1) Length = 559 Score = 43.1 bits (100), Expect = 5e-04 Identities = 21/76 (27%), Positives = 35/76 (46%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTHATTRPMGTSGYLDPEYYATSHLSEKSDVYSFGI 387 ILL D+ +I+DFG + S E +GT+ Y+ PE + SD+++ G Sbjct: 214 ILLNEDMHIQITDFGTAKVLSPESKQARANSFVGTAQYVSPELLTEKSACKSSDLWALGC 273 Query: 386 LLLVLITAQPVIVTAN 339 ++ L+ P N Sbjct: 274 IIYQLVAGLPPFRAGN 289
>PDPK1_HUMAN (O15530) 3-phosphoinositide-dependent protein kinase 1 (EC| 2.7.11.1) (hPDK1) Length = 556 Score = 43.1 bits (100), Expect = 5e-04 Identities = 21/76 (27%), Positives = 35/76 (46%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTHATTRPMGTSGYLDPEYYATSHLSEKSDVYSFGI 387 ILL D+ +I+DFG + S E +GT+ Y+ PE + SD+++ G Sbjct: 211 ILLNEDMHIQITDFGTAKVLSPESKQARANSFVGTAQYVSPELLTEKSACKSSDLWALGC 270 Query: 386 LLLVLITAQPVIVTAN 339 ++ L+ P N Sbjct: 271 IIYQLVAGLPPFRAGN 286
>STE7_CANAL (P46599) Serine/threonine-protein kinase STE7 homolog (EC 2.7.12.2)| Length = 589 Score = 42.7 bits (99), Expect = 7e-04 Identities = 24/71 (33%), Positives = 41/71 (57%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTHATTRPMGTSGYLDPEYYATSHLSEKSDVYSFGI 387 +L+T E ++ DFG++R ++ ++ T +GTS Y+ PE KSDV+S G+ Sbjct: 380 VLMTHKGEFKLCDFGVSRELTNSLAMADTF--VGTSMYMSPERIQGLDYGVKSDVWSTGL 437 Query: 386 LLLVLITAQPV 354 +L+ L + PV Sbjct: 438 MLIELASGVPV 448
>PKN1_CORGL (Q8NU98) Probable serine/threonine protein kinase pknB (EC| 2.7.11.1) Length = 646 Score = 42.7 bits (99), Expect = 7e-04 Identities = 22/71 (30%), Positives = 38/71 (53%), Gaps = 1/71 (1%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTHA-TTRPMGTSGYLDPEYYATSHLSEKSDVYSFG 390 I++T ++ DFG+ RA + S T+ +GT+ YL PE +SD+Y+ G Sbjct: 142 IMITNTGGVKVMDFGIARAVNDSTSAMTQTSAVIGTAQYLSPEQARGKPADARSDIYATG 201 Query: 389 ILLLVLITAQP 357 ++ L+T +P Sbjct: 202 CVMYELVTGKP 212
>PLK4_MOUSE (Q64702) Serine/threonine-protein kinase PLK4 (EC 2.7.11.21)| (Polo-like kinase 4) (PLK-4) (Serine/threonine-protein kinase Sak) (Serine/threonine-protein kinase 18) Length = 925 Score = 42.7 bits (99), Expect = 7e-04 Identities = 23/70 (32%), Positives = 35/70 (50%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTHATTRPMGTSGYLDPEYYATSHLSEKSDVYSFGI 387 ILLT ++ +I+DFGL + H T GT Y+ PE S +SD++S G Sbjct: 142 ILLTRNMNIKIADFGLATQLNMPHEKHYTL--CGTPNYISPEIATRSAHGLESDIWSLGC 199 Query: 386 LLLVLITAQP 357 + L+ +P Sbjct: 200 MFYTLLIGRP 209
>KRAF1_DROME (P11346) Raf homolog serine/threonine-protein kinase dRAF-1 (EC| 2.7.11.1) (Protein pole-hole) Length = 739 Score = 42.7 bits (99), Expect = 7e-04 Identities = 40/160 (25%), Positives = 70/160 (43%), Gaps = 4/160 (2%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTHATTRPMGTSGYLDPEYYATSHL---SEKSDVYS 396 I L DL +I DFGL A + +P G+ ++ PE L S +SDVY+ Sbjct: 554 IFLHEDLSVKIGDFGLATAKTRWSGEKQANQPTGSILWMAPEVIRMQELNPYSFQSDVYA 613 Query: 395 FGILLLVLITAQPVIVTANNAKRENISLWVRSRLLEGDIESLTDLRIRGHYDVNSVWKVA 216 FGI++ L+ + + + ++ I V LL D+ + ++ + Sbjct: 614 FGIVMYELLA--ECLPYGHISNKDQILFMVGRGLLRPDMSQVRS---------DAPQALK 662 Query: 215 EMALHCTEHKRQDRPTMMEVVEGLKEGLQ-LENSSRSSVE 99 +A C ++ +DRP ++ L+ L+ L RS+ E Sbjct: 663 RLAEDCIKYTPKDRPLFRPLLNMLENMLRTLPKIHRSASE 702
>RAF1_HUMAN (P04049) RAF proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (Raf-1) (C-RAF) (cRaf) Length = 648 Score = 42.4 bits (98), Expect = 0.001 Identities = 41/159 (25%), Positives = 65/159 (40%), Gaps = 6/159 (3%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTHATTRPMGTSGYLDPEYYA---TSHLSEKSDVYS 396 I L L +I DFGL S + +P G+ ++ PE + S +SDVYS Sbjct: 474 IFLHEGLTVKIGDFGLATVKSRWSGSQQVEQPTGSVLWMAPEVIRMQDNNPFSFQSDVYS 533 Query: 395 FGILLLVLITAQPVIVTANNAKRENISLWVRSRLLEGDIESLTDLRIRGHYDVNSVWKVA 216 +GI+L L+T + NN R+ I V D+ L N + Sbjct: 534 YGIVLYELMTGELPYSHINN--RDQIIFMVGRGYASPDLSKLYK---------NCPKAMK 582 Query: 215 EMALHCTEHKRQDRPTMMEV---VEGLKEGLQLENSSRS 108 + C + +++RP ++ +E L+ L N S S Sbjct: 583 RLVADCVKKVKEERPLFPQILSSIELLQHSLPKINRSAS 621
>M3K13_PONPY (Q5R8X7) Mitogen-activated protein kinase kinase kinase 13 (EC| 2.7.11.25) Length = 966 Score = 42.4 bits (98), Expect = 0.001 Identities = 23/69 (33%), Positives = 39/69 (56%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTHATTRPMGTSGYLDPEYYATSHLSEKSDVYSFGI 387 +L+T +ISDFG ++ S + + + GT +L PE +SEK D++SFG+ Sbjct: 285 VLVTHTDAVKISDFGTSKELSDKSTKMSFA---GTVAWLAPEVIRNEPVSEKVDIWSFGV 341 Query: 386 LLLVLITAQ 360 +L L+T + Sbjct: 342 VLWELLTGE 350
>TEC_HUMAN (P42680) Tyrosine-protein kinase Tec (EC 2.7.10.2)| Length = 631 Score = 42.0 bits (97), Expect = 0.001 Identities = 33/141 (23%), Positives = 64/141 (45%) Frame = -2 Query: 539 RISDFGLTRAFSSEMSTHATTRPMGTSGYLDPEYYATSHLSEKSDVYSFGILLLVLITAQ 360 ++SDFG+ R F + T ++ + PE + S S KSDV+SFG+L+ + T + Sbjct: 504 KVSDFGMARYFLDDQYTSSSGAKFPVK-WCPPEVFNYSRFSSKSDVWSFGVLMWEVFT-E 561 Query: 359 PVIVTANNAKRENISLWVRSRLLEGDIESLTDLRIRGHYDVNSVWKVAEMALHCTEHKRQ 180 + E +++ R L ++ +Y V E+ L C + K + Sbjct: 562 GRMPFEKYTNYEVVTMVTRG-------HRLYQPKLASNY-------VYEVMLRCWQEKPE 607 Query: 179 DRPTMMEVVEGLKEGLQLENS 117 RP+ +++ + E ++ E + Sbjct: 608 GRPSFEDLLRTIDELVECEET 628
>M3K11_HUMAN (Q16584) Mitogen-activated protein kinase kinase kinase 11 (EC| 2.7.11.25) (Mixed lineage kinase 3) (Src-homology 3 domain-containing proline-rich kinase) Length = 847 Score = 42.0 bits (97), Expect = 0.001 Identities = 25/62 (40%), Positives = 36/62 (58%), Gaps = 2/62 (3%) Frame = -2 Query: 539 RISDFGLTRAFSSEMSTHATTR--PMGTSGYLDPEYYATSHLSEKSDVYSFGILLLVLIT 366 +I+DFGL R + H TT+ GT ++ PE S S+ SDV+SFG+LL L+T Sbjct: 264 KITDFGLAREW------HKTTQMSAAGTYAWMAPEVIKASTFSKGSDVWSFGVLLWELLT 317 Query: 365 AQ 360 + Sbjct: 318 GE 319
>PKN1_COREF (Q8FUI5) Probable serine/threonine protein kinase CE0033 (EC| 2.7.11.1) Length = 660 Score = 42.0 bits (97), Expect = 0.001 Identities = 22/62 (35%), Positives = 32/62 (51%), Gaps = 1/62 (1%) Frame = -2 Query: 539 RISDFGLTRAFSSEMSTHATTRPM-GTSGYLDPEYYATSHLSEKSDVYSFGILLLVLITA 363 ++ DFG+ RA S T + GT+ YL PE +SDVY+ G +L L+T Sbjct: 151 KVMDFGIARALDDSTSAMTQTAAVIGTAQYLSPEQARGKPADARSDVYAAGCVLYELVTG 210 Query: 362 QP 357 +P Sbjct: 211 RP 212
>PKNE_MYCTU (P72001) Serine/threonine-protein kinase pknE (EC 2.7.11.1)| Length = 566 Score = 42.0 bits (97), Expect = 0.001 Identities = 23/70 (32%), Positives = 39/70 (55%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTHATTRPMGTSGYLDPEYYATSHLSEKSDVYSFGI 387 IL++AD A + DFG+ A + E T +GT Y+ PE ++ SH + ++D+Y+ Sbjct: 145 ILVSADDFAYLVDFGIASATTDEKLTQLGNT-VGTLYYMAPERFSESHATYRADIYALTC 203 Query: 386 LLLVLITAQP 357 +L +T P Sbjct: 204 VLYECLTGSP 213
>PKNE_MYCBO (Q7TZN3) Serine/threonine-protein kinase pknE (EC 2.7.11.1)| Length = 566 Score = 42.0 bits (97), Expect = 0.001 Identities = 23/70 (32%), Positives = 39/70 (55%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTHATTRPMGTSGYLDPEYYATSHLSEKSDVYSFGI 387 IL++AD A + DFG+ A + E T +GT Y+ PE ++ SH + ++D+Y+ Sbjct: 145 ILVSADDFAYLVDFGIASATTDEKLTQLGNT-VGTLYYMAPERFSESHATYRADIYALTC 203 Query: 386 LLLVLITAQP 357 +L +T P Sbjct: 204 VLYECLTGSP 213
>RAF1_RAT (P11345) RAF proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (Raf-1) (C-RAF) (cRaf) Length = 648 Score = 42.0 bits (97), Expect = 0.001 Identities = 41/159 (25%), Positives = 65/159 (40%), Gaps = 6/159 (3%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTHATTRPMGTSGYLDPEYYA---TSHLSEKSDVYS 396 I L L +I DFGL S + +P G+ ++ PE + S +SDVYS Sbjct: 474 IFLHEGLTVKIGDFGLATVKSRWSGSQQVEQPTGSVLWMAPEVIRMQDNNPFSFQSDVYS 533 Query: 395 FGILLLVLITAQPVIVTANNAKRENISLWVRSRLLEGDIESLTDLRIRGHYDVNSVWKVA 216 +GI+L L+T + NN R+ I V D+ L N + Sbjct: 534 YGIVLYELMTGELPYSHINN--RDQIIFMVGRGYASPDLSRLYK---------NCPKAMK 582 Query: 215 EMALHCTEHKRQDRPTMMEV---VEGLKEGLQLENSSRS 108 + C + +++RP ++ +E L+ L N S S Sbjct: 583 RLVADCVKKVKEERPLFPQILSSIELLQHSLPKINRSAS 621
>CTR1_ARATH (Q05609) Serine/threonine-protein kinase CTR1 (EC 2.7.11.1)| Length = 821 Score = 42.0 bits (97), Expect = 0.001 Identities = 24/69 (34%), Positives = 37/69 (53%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTHATTRPMGTSGYLDPEYYATSHLSEKSDVYSFGI 387 +L+ ++ DFGL+R +S + + GT ++ PE +EKSDVYSFG+ Sbjct: 682 LLVDKKYTVKVCDFGLSRLKASTFLSSKSAA--GTPEWMAPEVLRDEPSNEKSDVYSFGV 739 Query: 386 LLLVLITAQ 360 +L L T Q Sbjct: 740 ILWELATLQ 748
>PDPK1_RAT (O55173) 3-phosphoinositide-dependent protein kinase 1 (EC| 2.7.11.1) (Protein kinase B kinase) (PkB kinase) Length = 559 Score = 42.0 bits (97), Expect = 0.001 Identities = 20/76 (26%), Positives = 35/76 (46%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTHATTRPMGTSGYLDPEYYATSHLSEKSDVYSFGI 387 ILL D+ +I+DFG + S + +GT+ Y+ PE + SD+++ G Sbjct: 214 ILLNEDMHIQITDFGTAKVLSPDSKQARANSFVGTAQYVSPELLTEKSACKSSDLWALGC 273 Query: 386 LLLVLITAQPVIVTAN 339 ++ L+ P N Sbjct: 274 IIYQLVAGLPPFRAGN 289
>PLK4_HUMAN (O00444) Serine/threonine-protein kinase PLK4 (EC 2.7.11.21)| (Polo-like kinase 4) (PLK-4) (Serine/threonine-protein kinase Sak) (Serine/threonine-protein kinase 18) Length = 970 Score = 42.0 bits (97), Expect = 0.001 Identities = 23/70 (32%), Positives = 34/70 (48%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTHATTRPMGTSGYLDPEYYATSHLSEKSDVYSFGI 387 +LLT ++ +I+DFGL H T GT Y+ PE S +SDV+S G Sbjct: 142 LLLTRNMNIKIADFGLATQLKMPHEKHYTL--CGTPNYISPEIATRSAHGLESDVWSLGC 199 Query: 386 LLLVLITAQP 357 + L+ +P Sbjct: 200 MFYTLLIGRP 209
>PKNA2_BIFLO (Q8G4G1) Probable serine/threonine-protein kinase pknA2 (EC| 2.7.11.1) Length = 757 Score = 41.6 bits (96), Expect = 0.002 Identities = 22/69 (31%), Positives = 40/69 (57%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTHATTRPMGTSGYLDPEYYATSHLSEKSDVYSFGI 387 IL+ +I+DFGL +A +S+ + +T +GT+ YL PE + + + D+YS GI Sbjct: 146 ILINDRGHVQITDFGLAKA-ASQATLSSTGMLLGTAAYLAPEMIENNQATAQGDLYSVGI 204 Query: 386 LLLVLITAQ 360 + ++T + Sbjct: 205 MAWEMLTGK 213
>NEK1_MOUSE (P51954) Serine/threonine-protein kinase Nek1 (EC 2.7.11.1)| (NimA-related protein kinase 1) Length = 1203 Score = 41.6 bits (96), Expect = 0.002 Identities = 24/76 (31%), Positives = 36/76 (47%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTHATTRPMGTSGYLDPEYYATSHLSEKSDVYSFGI 387 I LT D ++ DFG+ R +S + T +GT YL PE + KSD+++ G Sbjct: 134 IFLTKDGTVQLGDFGIARVLNSTVELARTC--IGTPYYLSPEICENKPYNNKSDIWALGC 191 Query: 386 LLLVLITAQPVIVTAN 339 +L L T + N Sbjct: 192 VLYELCTLKHAFEAGN 207
>PKNB_BIFLO (Q8G6P9) Probable serine/threonine-protein kinase pknB (EC| 2.7.11.1) Length = 690 Score = 41.6 bits (96), Expect = 0.002 Identities = 21/71 (29%), Positives = 39/71 (54%), Gaps = 1/71 (1%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTHATTRPM-GTSGYLDPEYYATSHLSEKSDVYSFG 390 I+++ ++ DFG+ RA +T ++ + GT+ YL PE + +SD+YS G Sbjct: 152 IMISEQGVVKVMDFGIARALDDSAATMTQSQGVVGTAQYLSPEQARGETVDMRSDLYSAG 211 Query: 389 ILLLVLITAQP 357 +L ++T +P Sbjct: 212 CVLYEMLTGRP 222
>M3KSL_DROME (Q95UN8) Mitogen-activated protein kinase kinase kinase (EC| 2.7.11.25) (Mixed lineage kinase) (dMLK) (Protein slipper) Length = 1161 Score = 41.6 bits (96), Expect = 0.002 Identities = 24/60 (40%), Positives = 34/60 (56%) Frame = -2 Query: 539 RISDFGLTRAFSSEMSTHATTRPMGTSGYLDPEYYATSHLSEKSDVYSFGILLLVLITAQ 360 +I+DFGL R EM GT ++ PE + S S+ SDV+S+G+LL LIT + Sbjct: 287 KITDFGLAR----EMYNTQRMSAAGTYAWMPPEVISVSTYSKFSDVWSYGVLLWELITGE 342
>NRKA_TRYBB (Q08942) Putative serine/threonine-protein kinase A (EC 2.7.11.1)| Length = 431 Score = 41.6 bits (96), Expect = 0.002 Identities = 28/101 (27%), Positives = 50/101 (49%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTHATTRPMGTSGYLDPEYYATSHLSEKSDVYSFGI 387 +LLT+ ++ DFG + + +S + GT YL PE + ++K+DV+S G+ Sbjct: 153 VLLTSTGLVKLGDFGFSHQYEDTVSGVVASTFCGTPYYLAPELWNNKRYNKKADVWSLGV 212 Query: 386 LLLVLITAQPVIVTANNAKRENISLWVRSRLLEGDIESLTD 264 LL ++ + +A+N K + S++L G L D Sbjct: 213 LLYEIMGMKKPF-SASNLK------GLMSKVLAGTYAPLPD 246
>NEK9_XENLA (Q7ZZC8) Serine/threonine-protein kinase Nek9 (EC 2.7.11.1)| (NimA-related protein kinase 9) (XNek9) (Nercc1 kinase) Length = 944 Score = 41.6 bits (96), Expect = 0.002 Identities = 44/169 (26%), Positives = 74/169 (43%), Gaps = 11/169 (6%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTHATTRPMGTSGYLDPEYYATSHLSEKSDVYSFGI 387 I LT ++ D+GL + SSE S T +GT Y+ PE S KSD+++ G Sbjct: 164 IFLTKANLIKLGDYGLAKQLSSEYSMAETC--VGTLYYMSPEICQGVKYSFKSDIWAVGC 221 Query: 386 LLLVLITAQPVIVTANNAKRENISLWVRSRLLEGDIESLTDLRIRGHYDVNSVW--KVAE 213 +L L+T N ++L V ++++G+ D N+V+ ++ E Sbjct: 222 VLYELLTLTRTFDATN-----PLNLCV--KIVQGNWAVGLD---------NTVYTQELIE 265 Query: 212 MALHCTEHKRQDRPTMMEVVE---------GLKEGLQLENSSRSSVETG 93 + C E + RPT E++E ++E + + N S TG Sbjct: 266 VVHACLEQDPEKRPTADEILERPILSWRRRDMEEKVSMLNRSNKKPRTG 314
>M3K13_HUMAN (O43283) Mitogen-activated protein kinase kinase kinase 13 (EC| 2.7.11.25) (Mixed lineage kinase) (MLK) (Leucine zipper-bearing kinase) Length = 966 Score = 41.6 bits (96), Expect = 0.002 Identities = 22/69 (31%), Positives = 39/69 (56%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTHATTRPMGTSGYLDPEYYATSHLSEKSDVYSFGI 387 +L+T +ISDFG ++ S + + + GT ++ PE +SEK D++SFG+ Sbjct: 285 VLVTHTDAVKISDFGTSKELSDKSTKMSFA---GTVAWMAPEVIRNEPVSEKVDIWSFGV 341 Query: 386 LLLVLITAQ 360 +L L+T + Sbjct: 342 VLWELLTGE 350
>DSOR1_DROME (Q24324) Dual specificity mitogen-activated protein kinase kinase| dSOR1 (EC 2.7.12.2) (Downstream of RAF) (MAPKK) Length = 396 Score = 41.2 bits (95), Expect = 0.002 Identities = 25/83 (30%), Positives = 41/83 (49%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTHATTRPMGTSGYLDPEYYATSHLSEKSDVYSFGI 387 IL+ + E +I DFG++ M+ +GT Y+ PE +H S +SD++S G+ Sbjct: 215 ILVNSSGEIKICDFGVSGQLIDSMANSF----VGTRSYMSPERLQGTHYSVQSDIWSLGL 270 Query: 386 LLLVLITAQPVIVTANNAKRENI 318 L+ + I N A E+I Sbjct: 271 SLVEMAIGMYPIPPPNTATLESI 293
>M3K9_HUMAN (P80192) Mitogen-activated protein kinase kinase kinase 9 (EC| 2.7.11.25) (Mixed lineage kinase 1) Length = 1104 Score = 41.2 bits (95), Expect = 0.002 Identities = 24/62 (38%), Positives = 36/62 (58%), Gaps = 2/62 (3%) Frame = -2 Query: 539 RISDFGLTRAFSSEMSTHATTR--PMGTSGYLDPEYYATSHLSEKSDVYSFGILLLVLIT 366 +I+DFGL R + H TT+ GT ++ PE S S+ SDV+S+G+LL L+T Sbjct: 291 KITDFGLAREW------HRTTKMSAAGTYAWMAPEVIRASMFSKGSDVWSYGVLLWELLT 344 Query: 365 AQ 360 + Sbjct: 345 GE 346
>NEK1_HUMAN (Q96PY6) Serine/threonine-protein kinase Nek1 (EC 2.7.11.1)| (NimA-related protein kinase 1) (NY-REN-55 antigen) Length = 1258 Score = 41.2 bits (95), Expect = 0.002 Identities = 34/139 (24%), Positives = 62/139 (44%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTHATTRPMGTSGYLDPEYYATSHLSEKSDVYSFGI 387 I LT D ++ DFG+ R +S + T +GT YL PE + KSD+++ G Sbjct: 134 IFLTKDGTVQLGDFGIARVLNSTVELARTC--IGTPYYLSPEICENKPYNNKSDIWALGC 191 Query: 386 LLLVLITAQPVIVTANNAKRENISLWVRSRLLEGDIESLTDLRIRGHYDVNSVWKVAEMA 207 +L L T + + +N+ L +++ G S + + YD+ S + Sbjct: 192 VLYELCTLKHAFEAGS---MKNLVL----KIISG---SFPPVSLHYSYDLRS------LV 235 Query: 206 LHCTEHKRQDRPTMMEVVE 150 + +DRP++ ++E Sbjct: 236 SQLFKRNPRDRPSVNSILE 254
>IRAK3_HUMAN (Q9Y616) Interleukin-1 receptor-associated kinase 3 (EC 2.7.11.1)| (IRAK-3) (IL-1 receptor-associated kinase M) (IRAK-M) Length = 596 Score = 41.2 bits (95), Expect = 0.002 Identities = 25/78 (32%), Positives = 42/78 (53%), Gaps = 5/78 (6%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTHATTRPMGTSG-----YLDPEYYATSHLSEKSDV 402 ILL + +++DF + F S + + T M +S Y+ EY LS K+DV Sbjct: 299 ILLDDQFQPKLTDFAMAH-FRSHLEHQSCTINMTSSSSKHLWYMPEEYIRQGKLSIKTDV 357 Query: 401 YSFGILLLVLITAQPVIV 348 YSFGI+++ ++T V++ Sbjct: 358 YSFGIVIMEVLTGCRVVL 375
>TEC_MOUSE (P24604) Tyrosine-protein kinase Tec (EC 2.7.10.2)| Length = 630 Score = 41.2 bits (95), Expect = 0.002 Identities = 31/141 (21%), Positives = 63/141 (44%) Frame = -2 Query: 539 RISDFGLTRAFSSEMSTHATTRPMGTSGYLDPEYYATSHLSEKSDVYSFGILLLVLITAQ 360 ++SDFG+ R + T ++ + PE + S S KSDV+SFG+L+ + T + Sbjct: 503 KVSDFGMARYVLDDQYTSSSGAKFPVK-WCPPEVFNYSRFSSKSDVWSFGVLMWEIFT-E 560 Query: 359 PVIVTANNAKRENISLWVRSRLLEGDIESLTDLRIRGHYDVNSVWKVAEMALHCTEHKRQ 180 + N E +++ R L H + + E+ L C + + + Sbjct: 561 GRMPFEKNTNYEVVTMVTRGHRL--------------HRPKLATKYLYEVMLRCWQERPE 606 Query: 179 DRPTMMEVVEGLKEGLQLENS 117 RP++ +++ + E ++ E + Sbjct: 607 GRPSLEDLLRTIDELVECEET 627
>NEK2_HUMAN (P51955) Serine/threonine-protein kinase Nek2 (EC 2.7.11.1)| (NimA-related protein kinase 2) (NimA-like protein kinase 1) (HSPK 21) Length = 445 Score = 41.2 bits (95), Expect = 0.002 Identities = 44/161 (27%), Positives = 64/161 (39%), Gaps = 1/161 (0%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTHATTRPMGTSGYLDPEYYATSHLSEKSDVYSFGI 387 + L ++ DFGL R + + S T +GT Y+ PE +EKSD++S G Sbjct: 147 VFLDGKQNVKLGDFGLARILNHDTSFAKTF--VGTPYYMSPEQMNRMSYNEKSDIWSLGC 204 Query: 386 LLLVLITAQPVIVTANNAKRENISLWVRSRLLEGDIESLTDLRIRGHYDVNSVWKVAEMA 207 LL L P TA + K L G I RI Y ++ E+ Sbjct: 205 LLYELCALMPPF-TAFSQKE-----------LAGKIREGKFRRIPYRYSD----ELNEII 248 Query: 206 LHCTEHKRQDRPTMMEVVEG-LKEGLQLENSSRSSVETGRQ 87 K RP++ E++E L L + R+ GRQ Sbjct: 249 TRMLNLKDYHRPSVEEILENPLIADLVADEQRRNLERRGRQ 289
>MK14B_DROME (O61443) Mitogen-activated protein kinase 14B (EC 2.7.11.24) (MAP| kinase p38b) (D-p38b) Length = 365 Score = 40.8 bits (94), Expect = 0.003 Identities = 26/88 (29%), Positives = 44/88 (50%), Gaps = 1/88 (1%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTHATTRPMGTSGYLDPEYYAT-SHLSEKSDVYSFG 390 I + D E RI DFGL R SEM+ + TR Y PE H ++ +D++S G Sbjct: 159 IAVNEDCELRILDFGLARPAESEMTGYVATR-----WYRAPEIMLNWMHYNQTADIWSVG 213 Query: 389 ILLLVLITAQPVIVTANNAKRENISLWV 306 ++ L+T + + ++ + N+ + V Sbjct: 214 CIMAELLTGRTLFPGTDHIHQLNLIMEV 241
>RAF_MSV36 (P00532) Serine/threonine-protein kinase transforming protein raf| (EC 2.7.11.1) Length = 323 Score = 40.8 bits (94), Expect = 0.003 Identities = 34/145 (23%), Positives = 58/145 (40%), Gaps = 3/145 (2%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTHATTRPMGTSGYLDPEYYATSH---LSEKSDVYS 396 I L L +I DFGL S + +P G+ ++ PE S +SDVYS Sbjct: 149 IFLHEGLTVKIGDFGLATVKSRWSGSQQVEQPTGSVLWMAPEVIRMQDDNPFSFQSDVYS 208 Query: 395 FGILLLVLITAQPVIVTANNAKRENISLWVRSRLLEGDIESLTDLRIRGHYDVNSVWKVA 216 +GI+L L+ + NN R+ I V D+ L N + Sbjct: 209 YGIVLYELMAGELPYAHINN--RDQIIFMVGRGYASPDLSRLYK---------NCPKAIK 257 Query: 215 EMALHCTEHKRQDRPTMMEVVEGLK 141 + C + +++RP +++ ++ Sbjct: 258 RLVADCVKKVKEERPLFPQILSSIE 282
>PLK1_RAT (Q62673) Serine/threonine-protein kinase PLK1 (EC 2.7.11.21)| (Polo-like kinase 1) (PLK-1) Length = 603 Score = 40.8 bits (94), Expect = 0.003 Identities = 24/75 (32%), Positives = 35/75 (46%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTHATTRPMGTSGYLDPEYYATSHLSEKSDVYSFGI 387 + L DLE +I DFGL E T GT Y+ PE + S + DV+S G Sbjct: 182 LFLNEDLEVKIGDFGLATKVEYEGERKKTL--CGTPNYIAPEVLSKKGHSFEVDVWSIGC 239 Query: 386 LLLVLITAQPVIVTA 342 ++ L+ +P T+ Sbjct: 240 IMYTLLVGKPPFETS 254
>PLK1_MOUSE (Q07832) Serine/threonine-protein kinase PLK1 (EC 2.7.11.21)| (Polo-like kinase 1) (PLK-1) (Serine/threonine-protein kinase 13) (STPK13) Length = 603 Score = 40.8 bits (94), Expect = 0.003 Identities = 24/75 (32%), Positives = 35/75 (46%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTHATTRPMGTSGYLDPEYYATSHLSEKSDVYSFGI 387 + L DLE +I DFGL E T GT Y+ PE + S + DV+S G Sbjct: 182 LFLNEDLEVKIGDFGLATKVEYEGERKKTL--CGTPNYIAPEVLSKKGHSFEVDVWSIGC 239 Query: 386 LLLVLITAQPVIVTA 342 ++ L+ +P T+ Sbjct: 240 IMYTLLVGKPPFETS 254
>M3KL4_HUMAN (Q5TCX8) Mitogen-activated protein kinase kinase kinase (EC| 2.7.11.25) (Mixed lineage kinase 4) Length = 1036 Score = 40.8 bits (94), Expect = 0.003 Identities = 23/62 (37%), Positives = 37/62 (59%), Gaps = 2/62 (3%) Frame = -2 Query: 539 RISDFGLTRAFSSEMSTHATTR--PMGTSGYLDPEYYATSHLSEKSDVYSFGILLLVLIT 366 +I+DFGL R + H TT+ GT ++ PE +S S+ SD++S+G+LL L+T Sbjct: 286 KITDFGLAREW------HRTTKMSTAGTYAWMAPEVIKSSLFSKGSDIWSYGVLLWELLT 339 Query: 365 AQ 360 + Sbjct: 340 GE 341
>M3K7_HUMAN (O43318) Mitogen-activated protein kinase kinase kinase 7 (EC| 2.7.11.25) (Transforming growth factor-beta-activated kinase 1) (TGF-beta-activated kinase 1) Length = 606 Score = 40.8 bits (94), Expect = 0.003 Identities = 23/67 (34%), Positives = 39/67 (58%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTHATTRPMGTSGYLDPEYYATSHLSEKSDVYSFGI 387 +L+ +I DFG + ++ TH T G++ ++ PE + S+ SEK DV+S+GI Sbjct: 163 LLVAGGTVLKICDFGT----ACDIQTHMTNNK-GSAAWMAPEVFEGSNYSEKCDVFSWGI 217 Query: 386 LLLVLIT 366 +L +IT Sbjct: 218 ILWEVIT 224
>PKNA_MYCTU (P65726) Probable serine/threonine-protein kinase pknA (EC| 2.7.11.1) Length = 431 Score = 40.8 bits (94), Expect = 0.003 Identities = 23/61 (37%), Positives = 34/61 (55%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTHATTRPMGTSGYLDPEYYATSHLSEKSDVYSFGI 387 IL+T + +I+DFG+ +A + T T MGT+ Y+ PE S SDVYS G+ Sbjct: 147 ILITPTGQVKITDFGIAKAVDAAPVTQ-TGMVMGTAQYIAPEQALGHDASPASDVYSLGV 205 Query: 386 L 384 + Sbjct: 206 V 206
>PKNA_MYCBO (P65727) Probable serine/threonine-protein kinase pknA (EC| 2.7.11.1) Length = 431 Score = 40.8 bits (94), Expect = 0.003 Identities = 23/61 (37%), Positives = 34/61 (55%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTHATTRPMGTSGYLDPEYYATSHLSEKSDVYSFGI 387 IL+T + +I+DFG+ +A + T T MGT+ Y+ PE S SDVYS G+ Sbjct: 147 ILITPTGQVKITDFGIAKAVDAAPVTQ-TGMVMGTAQYIAPEQALGHDASPASDVYSLGV 205 Query: 386 L 384 + Sbjct: 206 V 206
>NRKB_TRYBB (Q03428) Putative serine/threonine-protein kinase B (EC 2.7.11.1)| Length = 431 Score = 40.8 bits (94), Expect = 0.003 Identities = 28/101 (27%), Positives = 50/101 (49%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTHATTRPMGTSGYLDPEYYATSHLSEKSDVYSFGI 387 +LLT+ ++ DFG + + +S + GT YL PE + ++K+DV+S G+ Sbjct: 153 VLLTSTGLVKLGDFGFSHQYEDTVSGVVASTFCGTPYYLAPELWNNLRYNKKADVWSLGV 212 Query: 386 LLLVLITAQPVIVTANNAKRENISLWVRSRLLEGDIESLTD 264 LL ++ + +A+N K + S++L G L D Sbjct: 213 LLYEIMGMKKPF-SASNLK------GLMSKVLAGTYAPLPD 246
>M3K7_MOUSE (Q62073) Mitogen-activated protein kinase kinase kinase 7 (EC| 2.7.11.25) (Transforming growth factor-beta-activated kinase 1) (TGF-beta-activated kinase 1) Length = 579 Score = 40.8 bits (94), Expect = 0.003 Identities = 23/67 (34%), Positives = 39/67 (58%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTHATTRPMGTSGYLDPEYYATSHLSEKSDVYSFGI 387 +L+ +I DFG + ++ TH T G++ ++ PE + S+ SEK DV+S+GI Sbjct: 163 LLVAGGTVLKICDFGT----ACDIQTHMTNNK-GSAAWMAPEVFEGSNYSEKCDVFSWGI 217 Query: 386 LLLVLIT 366 +L +IT Sbjct: 218 ILWEVIT 224
>SKM1_YEAST (Q12469) Serine/threonine-protein kinase SKM1 (EC 2.7.11.1)| (Protein kinase 75490 D) Length = 655 Score = 40.4 bits (93), Expect = 0.004 Identities = 24/70 (34%), Positives = 37/70 (52%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTHATTRPMGTSGYLDPEYYATSHLSEKSDVYSFGI 387 ILL + +I+DFG + + S AT +GT ++ PE EK DV+S GI Sbjct: 513 ILLNSQGLVKITDFGFCVELTEKRSKRATM--VGTPYWMAPEIVNQKGYDEKVDVWSLGI 570 Query: 386 LLLVLITAQP 357 +L+ +I +P Sbjct: 571 MLIEMIEGEP 580
>NEK3_HUMAN (P51956) Serine/threonine-protein kinase Nek3 (EC 2.7.11.1)| (NimA-related protein kinase 3) (HSPK 36) Length = 506 Score = 40.4 bits (93), Expect = 0.004 Identities = 23/67 (34%), Positives = 36/67 (53%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTHATTRPMGTSGYLDPEYYATSHLSEKSDVYSFGI 387 I LT + + ++ DFG R S+ M+ T +GT Y+ PE + + KSD++S G Sbjct: 133 IFLTQNGKVKLGDFGSARLLSNPMAFACTY--VGTPYYVPPEIWENLPYNNKSDIWSLGC 190 Query: 386 LLLVLIT 366 +L L T Sbjct: 191 ILYELCT 197
>TRK1_LYMST (O76997) Putative neurotrophin receptor LTRK 1 precursor (EC| 2.7.10.1) Length = 794 Score = 40.4 bits (93), Expect = 0.004 Identities = 39/144 (27%), Positives = 64/144 (44%), Gaps = 2/144 (1%) Frame = -2 Query: 563 LLTADLEARISDFGLTRAFSSEMSTHATTRPMGTSGYLDPEYYATSHLSEKSDVYSFGIL 384 L+ DL ++ DFG++R + M ++ PE + +SDV+SFG+ Sbjct: 654 LVGCDLVVKLGDFGMSRDVYTTDYYRVEGTAMLPVRWMPPESIIYRTFTTESDVWSFGVT 713 Query: 383 LLVLIT--AQPVIVTANNAKRENISLWVRSRLLEGDIESLTDLRIRGHYDVNSVWKVAEM 210 L + T QP +N+ E+I SR L+ + TD V++V + Sbjct: 714 LWEVFTYGKQPWFEYSNSEVIEHIK---NSRTLKRPPRTCTD----------GVYRVMQ- 759 Query: 209 ALHCTEHKRQDRPTMMEVVEGLKE 138 C + QDR TM ++ E L+E Sbjct: 760 --GCWKPNPQDRLTMKDIAELLRE 781
>RAF1_MOUSE (Q99N57) RAF proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (Raf-1) (C-RAF) (cRaf) Length = 648 Score = 40.4 bits (93), Expect = 0.004 Identities = 40/159 (25%), Positives = 63/159 (39%), Gaps = 6/159 (3%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTHATTRPMGTSGYLDPEYYATSH---LSEKSDVYS 396 I L L +I DFGL S + +P G+ ++ PE S +SDVYS Sbjct: 474 IFLHEGLTVKIGDFGLATVKSRWSGSQQVEQPTGSVLWMAPEVIRMQDDNPFSFQSDVYS 533 Query: 395 FGILLLVLITAQPVIVTANNAKRENISLWVRSRLLEGDIESLTDLRIRGHYDVNSVWKVA 216 +GI+L L+ + NN R+ I V D+ L N + Sbjct: 534 YGIVLYELMAGELPYAHINN--RDQIIFMVGRGYASPDLSRLYK---------NCPKAMK 582 Query: 215 EMALHCTEHKRQDRPTMMEV---VEGLKEGLQLENSSRS 108 + C + +++RP ++ +E L+ L N S S Sbjct: 583 RLVADCVKKVKEERPLFPQILSSIELLQHSLPKINRSAS 621
>RIPK3_RAT (Q9Z2P5) Receptor-interacting serine/threonine-protein kinase 3 (EC| 2.7.11.1) (RIP-like protein kinase 3) (Receptor-interacting protein 3) (RIP-3) (Homocysteine respondent protein HCYP2) Length = 478 Score = 40.4 bits (93), Expect = 0.004 Identities = 40/141 (28%), Positives = 64/141 (45%), Gaps = 5/141 (3%) Frame = -2 Query: 566 ILLTADLEARISDFGLT--RAFSSEMSTHATTRPMGTSGYLDPEYYATSHLSEK-SDVYS 396 +LL +L A+++DFGL+ + S S + GT YL PE + K SDVYS Sbjct: 149 VLLDLELHAKLADFGLSTFQGGSQSGSGSGSRDSGGTLAYLAPELLDNDGKASKASDVYS 208 Query: 395 FGILL-LVLITAQPVIVTANNAKRENI-SLWVRSRLLEGDIESLTDLRIRGHYDVNSVWK 222 FG+L+ VL + +V + R + + R L E +S + G Sbjct: 209 FGVLVWTVLAGREAEVVDKTSLIRGAVCNRQRRPPLTELPPDSPETPGLEG--------- 259 Query: 221 VAEMALHCTEHKRQDRPTMME 159 + E+ HC + +DRP+ + Sbjct: 260 LKELMTHCWSSEPKDRPSFQD 280
>NEK2_MOUSE (O35942) Serine/threonine-protein kinase Nek2 (EC 2.7.11.1)| (NimA-related protein kinase 2) Length = 443 Score = 40.4 bits (93), Expect = 0.004 Identities = 33/126 (26%), Positives = 53/126 (42%), Gaps = 5/126 (3%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTHATTRPMGTSGYLDPEYYATSHLSEKSDVYSFGI 387 + L + ++ DFGL R + + S T +GT Y+ PE + +EKSD++S Sbjct: 147 VFLDSKHNVKLGDFGLARILNHDTSFAKTF--VGTPYYMSPEQMSCLSYNEKSDIWSLAC 204 Query: 386 LLLVLITAQPVIVTANNAK-----RENISLWVRSRLLEGDIESLTDLRIRGHYDVNSVWK 222 LL L P N + RE + R +G + +T + Y SV + Sbjct: 205 LLYELCALMPPFTAFNQKELAGKIREGRFRRIPYRYSDGLNDLITRMLFLKDYHRPSVEE 264 Query: 221 VAEMAL 204 + E L Sbjct: 265 ILESPL 270
>NEK6_HUMAN (Q9HC98) Serine/threonine-protein kinase Nek6 (EC 2.7.11.1)| (NimA-related protein kinase 6) (Protein kinase SID6-1512) Length = 313 Score = 40.4 bits (93), Expect = 0.004 Identities = 25/69 (36%), Positives = 36/69 (52%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTHATTRPMGTSGYLDPEYYATSHLSEKSDVYSFGI 387 + +TA ++ D GL R FSSE T A +GT Y+ PE + + KSD++S G Sbjct: 178 VFITATGVVKLGDLGLGRFFSSE--TTAAHSLVGTPYYMSPERIHENGYNFKSDIWSLGC 235 Query: 386 LLLVLITAQ 360 LL + Q Sbjct: 236 LLYEMAALQ 244
>CSK_RAT (P32577) Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase)| Length = 450 Score = 40.0 bits (92), Expect = 0.005 Identities = 25/62 (40%), Positives = 33/62 (53%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTHATTRPMGTSGYLDPEYYATSHLSEKSDVYSFGI 387 +L++ D A++SDFGLT+ SS T + PE S KSDV+SFGI Sbjct: 320 VLVSEDNVAKVSDFGLTKEASSTQDTGKL-----PVKWTAPEALREKKFSTKSDVWSFGI 374 Query: 386 LL 381 LL Sbjct: 375 LL 376
>CSK_MOUSE (P41241) Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase)| (Protein-tyrosine kinase MPK-2) (p50CSK) Length = 450 Score = 40.0 bits (92), Expect = 0.005 Identities = 25/62 (40%), Positives = 33/62 (53%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTHATTRPMGTSGYLDPEYYATSHLSEKSDVYSFGI 387 +L++ D A++SDFGLT+ SS T + PE S KSDV+SFGI Sbjct: 320 VLVSEDNVAKVSDFGLTKEASSTQDTGKL-----PVKWTAPEALREKKFSTKSDVWSFGI 374 Query: 386 LL 381 LL Sbjct: 375 LL 376
>CSK_HUMAN (P41240) Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase)| (Protein-tyrosine kinase CYL) Length = 450 Score = 40.0 bits (92), Expect = 0.005 Identities = 25/62 (40%), Positives = 33/62 (53%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTHATTRPMGTSGYLDPEYYATSHLSEKSDVYSFGI 387 +L++ D A++SDFGLT+ SS T + PE S KSDV+SFGI Sbjct: 320 VLVSEDNVAKVSDFGLTKEASSTQDTGKL-----PVKWTAPEALREKKFSTKSDVWSFGI 374 Query: 386 LL 381 LL Sbjct: 375 LL 376
>PAK6_HUMAN (Q9NQU5) Serine/threonine-protein kinase PAK 6 (EC 2.7.11.1)| (p21-activated kinase 6) (PAK-6) (PAK-5) Length = 681 Score = 40.0 bits (92), Expect = 0.005 Identities = 20/70 (28%), Positives = 39/70 (55%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTHATTRPMGTSGYLDPEYYATSHLSEKSDVYSFGI 387 ILLT D ++SDFG S ++ + +GT ++ PE + S + + D++S GI Sbjct: 532 ILLTLDGRVKLSDFGFCAQISKDVPKRKSL--VGTPYWMAPEVISRSLYATEVDIWSLGI 589 Query: 386 LLLVLITAQP 357 +++ ++ +P Sbjct: 590 MVIEMVDGEP 599
>PKNA_MYCLE (P54743) Probable serine/threonine-protein kinase pknA (EC| 2.7.11.1) Length = 437 Score = 40.0 bits (92), Expect = 0.005 Identities = 22/61 (36%), Positives = 34/61 (55%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTHATTRPMGTSGYLDPEYYATSHLSEKSDVYSFGI 387 IL+T + +I+DFG+ +A + T T MGT+ Y+ PE + SDVYS G+ Sbjct: 147 ILITPTGQVKITDFGIAKAVDAAPVTQ-TGMVMGTAQYIAPEQALGHDATPASDVYSLGV 205 Query: 386 L 384 + Sbjct: 206 I 206
>PAK1_MOUSE (O88643) Serine/threonine-protein kinase PAK 1 (EC 2.7.11.1)| (p21-activated kinase 1) (PAK-1) (P65-PAK) (Alpha-PAK) (CDC42/RAC effector kinase PAK-A) Length = 545 Score = 40.0 bits (92), Expect = 0.005 Identities = 22/76 (28%), Positives = 37/76 (48%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTHATTRPMGTSGYLDPEYYATSHLSEKSDVYSFGI 387 ILL D +++DFG + E S +T +GT ++ PE K D++S GI Sbjct: 395 ILLGMDGSVKLTDFGFCAQITPEQSKRSTM--VGTPYWMAPEVVTRKAYGPKVDIWSLGI 452 Query: 386 LLLVLITAQPVIVTAN 339 + + +I +P + N Sbjct: 453 MAIEMIEGEPPYLNEN 468
>PAK1_HUMAN (Q13153) Serine/threonine-protein kinase PAK 1 (EC 2.7.11.1)| (p21-activated kinase 1) (PAK-1) (P65-PAK) (Alpha-PAK) Length = 545 Score = 40.0 bits (92), Expect = 0.005 Identities = 22/76 (28%), Positives = 37/76 (48%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTHATTRPMGTSGYLDPEYYATSHLSEKSDVYSFGI 387 ILL D +++DFG + E S +T +GT ++ PE K D++S GI Sbjct: 395 ILLGMDGSVKLTDFGFCAQITPEQSKRSTM--VGTPYWMAPEVVTRKAYGPKVDIWSLGI 452 Query: 386 LLLVLITAQPVIVTAN 339 + + +I +P + N Sbjct: 453 MAIEMIEGEPPYLNEN 468
>CLA4_CANAL (O14427) Serine/threonine-protein kinase CLA4 (EC 2.7.11.1)| Length = 971 Score = 40.0 bits (92), Expect = 0.005 Identities = 22/70 (31%), Positives = 36/70 (51%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTHATTRPMGTSGYLDPEYYATSHLSEKSDVYSFGI 387 +LL A +I+DFG + + + AT +GT ++ PE EK DV+S GI Sbjct: 809 VLLDAYGNVKITDFGFCAKLTDQRNKRATM--VGTPYWMAPEVVKQKEYDEKVDVWSLGI 866 Query: 386 LLLVLITAQP 357 + + +I +P Sbjct: 867 MTIEMIEGEP 876
>PKNH_MYCTU (Q11053) Probable serine/threonine-protein kinase pknH (EC| 2.7.11.1) Length = 626 Score = 40.0 bits (92), Expect = 0.005 Identities = 22/70 (31%), Positives = 38/70 (54%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTHATTRPMGTSGYLDPEYYATSHLSEKSDVYSFGI 387 IL+T D A + DFG+ A + E T T +GT Y+ PE ++ ++ ++D+Y+ Sbjct: 145 ILITRDDFAYLVDFGIASATTDEKLTQLGTA-VGTWKYMAPERFSNDEVTYRADIYALAC 203 Query: 386 LLLVLITAQP 357 +L +T P Sbjct: 204 VLHECLTGAP 213
>PAK1_RAT (P35465) Serine/threonine-protein kinase PAK 1 (EC 2.7.11.1)| (p21-activated kinase 1) (PAK-1) (P68-PAK) (Alpha-PAK) (Protein kinase MUK2) Length = 544 Score = 40.0 bits (92), Expect = 0.005 Identities = 22/76 (28%), Positives = 37/76 (48%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTHATTRPMGTSGYLDPEYYATSHLSEKSDVYSFGI 387 ILL D +++DFG + E S +T +GT ++ PE K D++S GI Sbjct: 394 ILLGMDGSVKLTDFGFCAQITPEQSKRSTM--VGTPYWMAPEVVTRKAYGPKVDIWSLGI 451 Query: 386 LLLVLITAQPVIVTAN 339 + + +I +P + N Sbjct: 452 MAIEMIEGEPPYLNEN 467
>MATK_MOUSE (P41242) Megakaryocyte-associated tyrosine-protein kinase (EC| 2.7.10.2) (Tyrosine-protein kinase CTK) (Protein kinase NTK) Length = 505 Score = 40.0 bits (92), Expect = 0.005 Identities = 24/62 (38%), Positives = 35/62 (56%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTHATTRPMGTSGYLDPEYYATSHLSEKSDVYSFGI 387 IL++ DL A++SDFGL +A ++ P+ + PE S KSDV+SFG+ Sbjct: 356 ILVSEDLVAKVSDFGLAKA--ERKGLDSSRLPVKWTA---PEALKNGRFSSKSDVWSFGV 410 Query: 386 LL 381 LL Sbjct: 411 LL 412
>PKNH_MYCBO (Q7U095) Probable serine/threonine-protein kinase pknH (EC| 2.7.11.1) Length = 596 Score = 40.0 bits (92), Expect = 0.005 Identities = 22/70 (31%), Positives = 38/70 (54%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTHATTRPMGTSGYLDPEYYATSHLSEKSDVYSFGI 387 IL+T D A + DFG+ A + E T T +GT Y+ PE ++ ++ ++D+Y+ Sbjct: 145 ILITRDDFAYLVDFGIASATTDEKLTQLGTA-VGTWKYMAPERFSNDEVTYRADIYALAC 203 Query: 386 LLLVLITAQP 357 +L +T P Sbjct: 204 VLHECLTGAP 213
>NEK6_RAT (P59895) Serine/threonine-protein kinase Nek6 (EC 2.7.11.1)| (NimA-related protein kinase 6) Length = 313 Score = 40.0 bits (92), Expect = 0.005 Identities = 25/69 (36%), Positives = 36/69 (52%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTHATTRPMGTSGYLDPEYYATSHLSEKSDVYSFGI 387 + +TA ++ D GL R FSSE T A +GT Y+ PE + + KSD++S G Sbjct: 178 VFITATGIVKLGDLGLGRFFSSE--TTAAHSLVGTPYYMSPERIHENGYNFKSDIWSLGC 235 Query: 386 LLLVLITAQ 360 LL + Q Sbjct: 236 LLYEMAALQ 244
>NEK6_MOUSE (Q9ES70) Serine/threonine-protein kinase Nek6 (EC 2.7.11.1)| (NimA-related protein kinase 6) Length = 313 Score = 40.0 bits (92), Expect = 0.005 Identities = 25/69 (36%), Positives = 36/69 (52%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTHATTRPMGTSGYLDPEYYATSHLSEKSDVYSFGI 387 + +TA ++ D GL R FSSE T A +GT Y+ PE + + KSD++S G Sbjct: 178 VFITATGIVKLGDLGLGRFFSSE--TTAAHSLVGTPYYMSPERIHENGYNFKSDIWSLGC 235 Query: 386 LLLVLITAQ 360 LL + Q Sbjct: 236 LLYEMAALQ 244
>KPC1_LYTPI (Q25378) Protein kinase C (EC 2.7.11.13)| Length = 658 Score = 40.0 bits (92), Expect = 0.005 Identities = 22/70 (31%), Positives = 37/70 (52%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTHATTRPMGTSGYLDPEYYATSHLSEKSDVYSFGI 387 +L+ A+ +I+DFG+ + +E T T GT Y+ PE A + D ++FG+ Sbjct: 455 VLVDAEGHIKIADFGMCKEHMNEGDTTRTF--CGTPDYIAPEIVAYQPYGKAVDWWAFGV 512 Query: 386 LLLVLITAQP 357 LL ++ QP Sbjct: 513 LLYEMLAGQP 522
>PAK3_PONPY (Q7YQL3) Serine/threonine-protein kinase PAK 3 (EC 2.7.11.1)| (p21-activated kinase 3) (PAK-3) Length = 559 Score = 39.7 bits (91), Expect = 0.006 Identities = 21/76 (27%), Positives = 37/76 (48%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTHATTRPMGTSGYLDPEYYATSHLSEKSDVYSFGI 387 ILL D +++DFG + E S +T +GT ++ PE K D++S GI Sbjct: 408 ILLGMDGSVKLTDFGFCAQITPEQSKRSTM--VGTPYWMAPEVVTRKAYGPKVDIWSLGI 465 Query: 386 LLLVLITAQPVIVTAN 339 + + ++ +P + N Sbjct: 466 MAIEMVEGEPPYLNEN 481
>PAK3_PANTR (Q7YQL4) Serine/threonine-protein kinase PAK 3 (EC 2.7.11.1)| (p21-activated kinase 3) (PAK-3) Length = 559 Score = 39.7 bits (91), Expect = 0.006 Identities = 21/76 (27%), Positives = 37/76 (48%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTHATTRPMGTSGYLDPEYYATSHLSEKSDVYSFGI 387 ILL D +++DFG + E S +T +GT ++ PE K D++S GI Sbjct: 408 ILLGMDGSVKLTDFGFCAQITPEQSKRSTM--VGTPYWMAPEVVTRKAYGPKVDIWSLGI 465 Query: 386 LLLVLITAQPVIVTAN 339 + + ++ +P + N Sbjct: 466 MAIEMVEGEPPYLNEN 481
>PAK3_MOUSE (Q61036) Serine/threonine-protein kinase PAK 3 (EC 2.7.11.1)| (p21-activated kinase 3) (PAK-3) (Beta-PAK) (CDC42/RAC effector kinase PAK-B) Length = 559 Score = 39.7 bits (91), Expect = 0.006 Identities = 21/76 (27%), Positives = 37/76 (48%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTHATTRPMGTSGYLDPEYYATSHLSEKSDVYSFGI 387 ILL D +++DFG + E S +T +GT ++ PE K D++S GI Sbjct: 408 ILLGMDGSVKLTDFGFCAQITPEQSKRSTM--VGTPYWMAPEVVTRKAYGPKVDIWSLGI 465 Query: 386 LLLVLITAQPVIVTAN 339 + + ++ +P + N Sbjct: 466 MAIEMVEGEPPYLNEN 481
>PAK3_HUMAN (O75914) Serine/threonine-protein kinase PAK 3 (EC 2.7.11.1)| (p21-activated kinase 3) (PAK-3) (Beta-PAK) (Oligophrenin-3) Length = 559 Score = 39.7 bits (91), Expect = 0.006 Identities = 21/76 (27%), Positives = 37/76 (48%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTHATTRPMGTSGYLDPEYYATSHLSEKSDVYSFGI 387 ILL D +++DFG + E S +T +GT ++ PE K D++S GI Sbjct: 408 ILLGMDGSVKLTDFGFCAQITPEQSKRSTM--VGTPYWMAPEVVTRKAYGPKVDIWSLGI 465 Query: 386 LLLVLITAQPVIVTAN 339 + + ++ +P + N Sbjct: 466 MAIEMVEGEPPYLNEN 481
>PAK1_CAEEL (Q17850) Serine/threonine-protein kinase pak-1 (EC 2.7.11.1)| (p21-activated kinase 1) (PAK1) (CePAK) Length = 572 Score = 39.7 bits (91), Expect = 0.006 Identities = 22/76 (28%), Positives = 35/76 (46%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTHATTRPMGTSGYLDPEYYATSHLSEKSDVYSFGI 387 ILL D +++DFG S E T +GT ++ PE K DV+S GI Sbjct: 420 ILLGMDGSVKLTDFGFCAQLSPEQRKRTTM--VGTPYWMAPEVVTRKQYGPKVDVWSLGI 477 Query: 386 LLLVLITAQPVIVTAN 339 + + ++ +P + N Sbjct: 478 MAIEMVEGEPPYLNEN 493
>CLA4_YEAST (P48562) Serine/threonine-protein kinase CLA4 (EC 2.7.11.1)| Length = 842 Score = 39.7 bits (91), Expect = 0.006 Identities = 21/70 (30%), Positives = 35/70 (50%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTHATTRPMGTSGYLDPEYYATSHLSEKSDVYSFGI 387 +LL +I+DFG + + S AT +GT ++ PE EK DV+S GI Sbjct: 699 VLLDTRARVKITDFGFCARLTDKRSKRATM--VGTPYWMAPEVVKQREYDEKIDVWSLGI 756 Query: 386 LLLVLITAQP 357 + + ++ +P Sbjct: 757 MTIEMLEGEP 766
>YS3J_CAEEL (Q19238) Putative tyrosine-protein kinase F09A5.2 in chromosome X| (EC 2.7.10.1) Length = 894 Score = 39.7 bits (91), Expect = 0.006 Identities = 26/68 (38%), Positives = 37/68 (54%), Gaps = 1/68 (1%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTHATTR-PMGTSGYLDPEYYATSHLSEKSDVYSFG 390 ILLT L A++SDFGL R S + T R P+ ++ E S K+DV+SFG Sbjct: 659 ILLTKSLTAKVSDFGLCRYMDSALYTAKGGRLPI---KWMSVEALKLYEFSTKTDVWSFG 715 Query: 389 ILLLVLIT 366 +LL + + Sbjct: 716 VLLFEIFS 723
>MATK_RAT (P41243) Megakaryocyte-associated tyrosine-protein kinase (EC| 2.7.10.2) (Tyrosine-protein kinase CTK) (Protein kinase BATK) Length = 467 Score = 39.7 bits (91), Expect = 0.006 Identities = 24/62 (38%), Positives = 35/62 (56%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTHATTRPMGTSGYLDPEYYATSHLSEKSDVYSFGI 387 IL++ DL A++SDFGL +A ++ P+ + PE S KSDV+SFG+ Sbjct: 317 ILVSEDLVAKVSDFGLAKA-ELRKGLDSSRLPVKWTA---PEALKNGRFSSKSDVWSFGV 372 Query: 386 LL 381 LL Sbjct: 373 LL 374
>PKND_MYCTU (O05871) Serine/threonine-protein kinase pknD (EC 2.7.11.1)| Length = 664 Score = 39.7 bits (91), Expect = 0.006 Identities = 23/70 (32%), Positives = 37/70 (52%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTHATTRPMGTSGYLDPEYYATSHLSEKSDVYSFGI 387 IL+TA A + DFG+ RA S T T +GT Y+ PE + ++ ++D+Y+ Sbjct: 144 ILVTASDFAYLVDFGIARAASDPGLTQTGTA-VGTYNYMAPERFTGDEVTYRADIYALAC 202 Query: 386 LLLVLITAQP 357 +L +T P Sbjct: 203 VLGECLTGAP 212
>KPCG_RAT (P63319) Protein kinase C gamma type (EC 2.7.11.13) (PKC-gamma)| Length = 697 Score = 39.7 bits (91), Expect = 0.006 Identities = 23/71 (32%), Positives = 38/71 (53%), Gaps = 1/71 (1%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTHATTRPM-GTSGYLDPEYYATSHLSEKSDVYSFG 390 ++L A+ +I+DFG+ + + +TTR GT Y+ PE A + D +SFG Sbjct: 486 VMLDAEGHIKITDFGMCK---ENVFPGSTTRTFCGTPDYIAPEIIAYQPYGKSVDWWSFG 542 Query: 389 ILLLVLITAQP 357 +LL ++ QP Sbjct: 543 VLLYEMLAGQP 553
>KPCG_MOUSE (P63318) Protein kinase C gamma type (EC 2.7.11.13) (PKC-gamma)| Length = 697 Score = 39.7 bits (91), Expect = 0.006 Identities = 23/71 (32%), Positives = 38/71 (53%), Gaps = 1/71 (1%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTHATTRPM-GTSGYLDPEYYATSHLSEKSDVYSFG 390 ++L A+ +I+DFG+ + + +TTR GT Y+ PE A + D +SFG Sbjct: 486 VMLDAEGHIKITDFGMCK---ENVFPGSTTRTFCGTPDYIAPEIIAYQPYGKSVDWWSFG 542 Query: 389 ILLLVLITAQP 357 +LL ++ QP Sbjct: 543 VLLYEMLAGQP 553
>PAKM_DROME (Q9VXE5) Serine/threonine-protein kinase PAK mbt (EC 2.7.11.1)| (p21-activated kinase-related protein) (Protein mushroom bodies tiny) Length = 639 Score = 39.7 bits (91), Expect = 0.006 Identities = 20/70 (28%), Positives = 37/70 (52%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTHATTRPMGTSGYLDPEYYATSHLSEKSDVYSFGI 387 ILL AD ++SDFG S E+ + +GT ++ PE + + D++S GI Sbjct: 493 ILLAADGRVKLSDFGFCAQVSQELPKRKSL--VGTPYWMSPEVISRLPYGPEVDIWSLGI 550 Query: 386 LLLVLITAQP 357 +++ ++ +P Sbjct: 551 MVIEMVDGEP 560
>PKN2_COREF (Q8FUI4) Serine/threonine protein kinases drp72 (EC 2.7.11.1)| Length = 520 Score = 39.7 bits (91), Expect = 0.006 Identities = 22/61 (36%), Positives = 37/61 (60%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTHATTRPMGTSGYLDPEYYATSHLSEKSDVYSFGI 387 +L+TA+ +I+DFG+ +A +S T T +GT+ Y+ PE ++ SDVYS G+ Sbjct: 154 MLITANGILKITDFGIAKAAASVPLTR-TGMVVGTAQYVSPEQAQGHQVTPASDVYSLGV 212 Query: 386 L 384 + Sbjct: 213 V 213
>PLK1_HUMAN (P53350) Serine/threonine-protein kinase PLK1 (EC 2.7.11.21)| (Polo-like kinase 1) (PLK-1) (Serine/threonine-protein kinase 13) (STPK13) Length = 603 Score = 39.7 bits (91), Expect = 0.006 Identities = 24/75 (32%), Positives = 35/75 (46%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTHATTRPMGTSGYLDPEYYATSHLSEKSDVYSFGI 387 + L DLE +I DFGL A E GT Y+ PE + S + DV+S G Sbjct: 182 LFLNEDLEVKIGDFGL--ATKVEYDGERKKTLCGTPNYIAPEVLSKKGHSFEVDVWSIGC 239 Query: 386 LLLVLITAQPVIVTA 342 ++ L+ +P T+ Sbjct: 240 IMYTLLVGKPPFETS 254
>PAK3_RAT (Q62829) Serine/threonine-protein kinase PAK 3 (EC 2.7.11.1)| (p21-activated kinase 3) (PAK-3) (Beta-PAK) (p65-PAK) Length = 544 Score = 39.7 bits (91), Expect = 0.006 Identities = 21/76 (27%), Positives = 37/76 (48%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTHATTRPMGTSGYLDPEYYATSHLSEKSDVYSFGI 387 ILL D +++DFG + E S +T +GT ++ PE K D++S GI Sbjct: 393 ILLGMDGSVKLTDFGFCAQITPEQSKRSTM--VGTPYWMAPEVVTRKAYGPKVDIWSLGI 450 Query: 386 LLLVLITAQPVIVTAN 339 + + ++ +P + N Sbjct: 451 MAIEMVEGEPPYLNEN 466
>NEK1_CAEEL (P84199) Serine/threonine-protein kinase D1044.8 (EC 2.7.11.1)| Length = 959 Score = 39.7 bits (91), Expect = 0.006 Identities = 25/76 (32%), Positives = 35/76 (46%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTHATTRPMGTSGYLDPEYYATSHLSEKSDVYSFGI 387 I++T D I+DFGL + E A GT Y PE EK+D++SFG Sbjct: 575 IMMTTDERVVITDFGLAKQKGPEYLKSAA----GTIIYSCPEIVQNLPYGEKADIWSFGC 630 Query: 386 LLLVLITAQPVIVTAN 339 + + QPV + N Sbjct: 631 CIYEMCQLQPVFHSTN 646
>E2AK2_MOUSE (Q03963) Interferon-induced, double-stranded RNA-activated protein| kinase (EC 2.7.11.1) (Interferon-inducible RNA-dependent protein kinase) (Protein kinase RNA-activated) (PKR) (p68 kinase) (P1/eIF-2A protein kinase) (Serine/threonine-protein Length = 515 Score = 39.7 bits (91), Expect = 0.006 Identities = 20/66 (30%), Positives = 34/66 (51%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTHATTRPMGTSGYLDPEYYATSHLSEKSDVYSFGI 387 I L + +I DFGL A ++ + TR GT Y+ PE H ++ D+++ G+ Sbjct: 382 IFLVDERHIKIGDFGLATALENDGKSR--TRRTGTLQYMSPEQLFLKHYGKEVDIFALGL 439 Query: 386 LLLVLI 369 +L L+ Sbjct: 440 ILAELL 445
>CSK_CHICK (P41239) Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase)| Length = 450 Score = 39.7 bits (91), Expect = 0.006 Identities = 25/62 (40%), Positives = 33/62 (53%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTHATTRPMGTSGYLDPEYYATSHLSEKSDVYSFGI 387 +L++ D A++SDFGLT+ SS T + PE S KSDV+SFGI Sbjct: 320 VLVSEDNIAKVSDFGLTKEASSTQDTGKL-----PVKWTAPEALREKKFSTKSDVWSFGI 374 Query: 386 LL 381 LL Sbjct: 375 LL 376
>KPCG_BOVIN (P05128) Protein kinase C gamma type (EC 2.7.11.13) (PKC-gamma)| (Fragment) Length = 682 Score = 39.7 bits (91), Expect = 0.006 Identities = 23/71 (32%), Positives = 38/71 (53%), Gaps = 1/71 (1%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTHATTRPM-GTSGYLDPEYYATSHLSEKSDVYSFG 390 ++L A+ +I+DFG+ + + +TTR GT Y+ PE A + D +SFG Sbjct: 471 VMLDAEGHIKITDFGMCK---ENVFPGSTTRTFCGTPDYIAPEIIAYQPYGKSVDWWSFG 527 Query: 389 ILLLVLITAQP 357 +LL ++ QP Sbjct: 528 VLLYEMLAGQP 538
>PAK7_MOUSE (Q8C015) Serine/threonine-protein kinase PAK 7 (EC 2.7.11.1)| (p21-activated kinase 7) (PAK-7) (p21-activated kinase 5) Length = 719 Score = 39.3 bits (90), Expect = 0.008 Identities = 21/70 (30%), Positives = 38/70 (54%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTHATTRPMGTSGYLDPEYYATSHLSEKSDVYSFGI 387 ILLT+D ++SDFG S E+ + +GT ++ PE + + D++S GI Sbjct: 574 ILLTSDGRIKLSDFGFCAQVSKEVPKRKSL--VGTPYWMAPEVISRLPYGTEVDIWSLGI 631 Query: 386 LLLVLITAQP 357 +++ +I +P Sbjct: 632 MVIEMIDGEP 641
>PAK7_HUMAN (Q9P286) Serine/threonine-protein kinase PAK 7 (EC 2.7.11.1)| (p21-activated kinase 7) (PAK-7) (PAK-5) Length = 719 Score = 39.3 bits (90), Expect = 0.008 Identities = 21/70 (30%), Positives = 38/70 (54%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTHATTRPMGTSGYLDPEYYATSHLSEKSDVYSFGI 387 ILLT+D ++SDFG S E+ + +GT ++ PE + + D++S GI Sbjct: 574 ILLTSDGRIKLSDFGFCAQVSKEVPKRKSL--VGTPYWMAPEVISRLPYGTEVDIWSLGI 631 Query: 386 LLLVLITAQP 357 +++ +I +P Sbjct: 632 MVIEMIDGEP 641
>INSR_AEDAE (Q93105) Insulin-like receptor precursor (EC 2.7.10.1) (MIR)| [Contains: Insulin-like receptor alpha chain; Insulin-like receptor beta chain] Length = 1390 Score = 39.3 bits (90), Expect = 0.008 Identities = 31/142 (21%), Positives = 58/142 (40%), Gaps = 2/142 (1%) Frame = -2 Query: 563 LLTADLEARISDFGLTRAFSSEMSTHATTRPMGTSGYLDPEYYATSHLSEKSDVYSFGIL 384 ++ D+ +I DFG+TR T+ ++ PE S SDV+S+G++ Sbjct: 1169 MVADDMTVKIGDFGMTRDIYETDYYRKGTKGFLPVRWMAPESLKDGIFSSSSDVFSYGVV 1228 Query: 383 L--LVLITAQPVIVTANNAKRENISLWVRSRLLEGDIESLTDLRIRGHYDVNSVWKVAEM 210 L + + +QP N+ V +++G + + N + + Sbjct: 1229 LWEMATLASQPYQGLTNDQ--------VLRYVIDGGVMERPE---------NCPDNLYNL 1271 Query: 209 ALHCTEHKRQDRPTMMEVVEGL 144 C +H+ RPT ME++ L Sbjct: 1272 MRRCWQHRPTARPTFMEIISEL 1293
>FGFR1_DROME (Q07407) Fibroblast growth factor receptor homolog 1 precursor (EC| 2.7.10.1) (Protein heartless) Length = 729 Score = 39.3 bits (90), Expect = 0.008 Identities = 37/150 (24%), Positives = 58/150 (38%), Gaps = 4/150 (2%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTHATTRPMGTSGYLDPEYYATSHLSEKSDVYSFGI 387 +L++ D +I+DFGL R S T ++ PE KSDV+S+GI Sbjct: 562 VLVSDDYVLKIADFGLARDIQSTDYYRKNTNGRLPIKWMAPESLQEKFYDSKSDVWSYGI 621 Query: 386 LLLVLIT----AQPVIVTANNAKRENISLWVRSRLLEGDIESLTDLRIRGHYDVNSVWKV 219 LL ++T P I++A + + L+ G R + Sbjct: 622 LLWEIMTYGQQPYPTIMSAEE---------LYTYLMSGQ---------RMEKPAKCSMNI 663 Query: 218 AEMALHCTEHKRQDRPTMMEVVEGLKEGLQ 129 + C DRP E+VE + + LQ Sbjct: 664 YILMRQCWHFNADDRPPFTEIVEYMDKLLQ 693
>ANKK1_HUMAN (Q8NFD2) Ankyrin repeat and protein kinase domain-containing| protein 1 (EC 2.7.11.1) (Protein kinase PKK2) (X-kinase) (SgK288) Length = 765 Score = 39.3 bits (90), Expect = 0.008 Identities = 25/71 (35%), Positives = 40/71 (56%), Gaps = 4/71 (5%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAF--SSEMSTHATTRPMGTSGYLDPEYYATSHLS--EKSDVY 399 ILL +++ +ISDFGL++ S+ M + G Y+ PE + S+ + K DVY Sbjct: 151 ILLDSNMHVKISDFGLSKWMEQSTRMQYIERSALRGMLSYIPPEMFLESNKAPGPKYDVY 210 Query: 398 SFGILLLVLIT 366 SF I++ L+T Sbjct: 211 SFAIVIWELLT 221
>NEK3_MOUSE (Q9R0A5) Serine/threonine-protein kinase Nek3 (EC 2.7.11.1)| (NimA-related protein kinase 3) Length = 511 Score = 39.3 bits (90), Expect = 0.008 Identities = 22/65 (33%), Positives = 35/65 (53%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTHATTRPMGTSGYLDPEYYATSHLSEKSDVYSFGI 387 + LT + + ++ DFG R SS M+ T +GT Y+ PE + + KSD++S G Sbjct: 131 VFLTHNGKVKLGDFGSARLLSSPMAFACTY--VGTPYYVPPEIWENLPYNNKSDIWSLGC 188 Query: 386 LLLVL 372 +L L Sbjct: 189 ILYEL 193
>KPCG_RABIT (P10829) Protein kinase C gamma type (EC 2.7.11.13) (PKC-gamma)| (PKC-delta) Length = 697 Score = 39.3 bits (90), Expect = 0.008 Identities = 23/71 (32%), Positives = 37/71 (52%), Gaps = 1/71 (1%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTHATTRPM-GTSGYLDPEYYATSHLSEKSDVYSFG 390 ++L A+ +I+DFG+ + + TTR GT Y+ PE A + D +SFG Sbjct: 486 VMLDAEGHIKITDFGMCK---ENVFPGTTTRTFCGTPDYIAPEIIAYQPYGKSVDWWSFG 542 Query: 389 ILLLVLITAQP 357 +LL ++ QP Sbjct: 543 VLLYEMLAGQP 553
>KPCG_HUMAN (P05129) Protein kinase C gamma type (EC 2.7.11.13) (PKC-gamma)| Length = 697 Score = 39.3 bits (90), Expect = 0.008 Identities = 23/71 (32%), Positives = 37/71 (52%), Gaps = 1/71 (1%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTHATTRPM-GTSGYLDPEYYATSHLSEKSDVYSFG 390 ++L A+ +I+DFG+ + + TTR GT Y+ PE A + D +SFG Sbjct: 486 VMLDAEGHIKITDFGMCK---ENVFPGTTTRTFCGTPDYIAPEIIAYQPYGKSVDWWSFG 542 Query: 389 ILLLVLITAQP 357 +LL ++ QP Sbjct: 543 VLLYEMLAGQP 553
>BMX_MOUSE (P97504) Cytoplasmic tyrosine-protein kinase BMX (EC 2.7.10.2)| (Bone marrow tyrosine kinase gene in chromosome X protein homolog) Length = 651 Score = 39.3 bits (90), Expect = 0.008 Identities = 24/63 (38%), Positives = 37/63 (58%), Gaps = 2/63 (3%) Frame = -2 Query: 563 LLTADLEARISDFGLTRAFSSE--MSTHATTRPMGTSGYLDPEYYATSHLSEKSDVYSFG 390 L+ +DL ++SDFG+TR + +S+ T P+ S PE + S KSDV++FG Sbjct: 519 LVDSDLSVKVSDFGMTRYVLDDQYVSSVGTKFPVKWSA---PEVFHYFKYSSKSDVWAFG 575 Query: 389 ILL 381 IL+ Sbjct: 576 ILM 578
>E2AK3_RAT (Q9Z1Z1) Eukaryotic translation initiation factor 2-alpha kinase 3| precursor (EC 2.7.11.1) (PRKR-like endoplasmic reticulum kinase) (Pancreatic eIF2-alpha kinase) Length = 1108 Score = 39.3 bits (90), Expect = 0.008 Identities = 22/76 (28%), Positives = 33/76 (43%), Gaps = 10/76 (13%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTHATTRPM----------GTSGYLDPEYYATSHLS 417 I T D ++ DFGL A + PM GT Y+ PE ++ S Sbjct: 935 IFFTMDDVVKVGDFGLVTAMDQDEEEQTVLTPMPAYATHTGQVGTKLYMSPEQIHGNNYS 994 Query: 416 EKSDVYSFGILLLVLI 369 K D++S G++L L+ Sbjct: 995 HKVDIFSLGLILFELL 1010
>E2AK3_MOUSE (Q9Z2B5) Eukaryotic translation initiation factor 2-alpha kinase 3| precursor (EC 2.7.11.1) (PRKR-like endoplasmic reticulum kinase) (Pancreatic eIF2-alpha kinase) Length = 1114 Score = 39.3 bits (90), Expect = 0.008 Identities = 22/76 (28%), Positives = 33/76 (43%), Gaps = 10/76 (13%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTHATTRPM----------GTSGYLDPEYYATSHLS 417 I T D ++ DFGL A + PM GT Y+ PE ++ S Sbjct: 941 IFFTMDDVVKVGDFGLVTAMDQDEEEQTVLTPMPAYATHTGQVGTKLYMSPEQIHGNNYS 1000 Query: 416 EKSDVYSFGILLLVLI 369 K D++S G++L L+ Sbjct: 1001 HKVDIFSLGLILFELL 1016
>TXK_HUMAN (P42681) Tyrosine-protein kinase TXK (EC 2.7.10.2)| Length = 527 Score = 39.3 bits (90), Expect = 0.008 Identities = 42/146 (28%), Positives = 66/146 (45%), Gaps = 4/146 (2%) Frame = -2 Query: 563 LLTADLEARISDFGLTRAFSSE--MSTHATTRPMGTSGYLDPEYYATSHLSEKSDVYSFG 390 L+++ +ISDFG+TR + +S+ P+ S PE + + S KSDV+SFG Sbjct: 397 LVSSTCIVKISDFGMTRYVLDDEYVSSFGAKFPIKWS---PPEVFLFNKYSSKSDVWSFG 453 Query: 389 ILLLVLITAQPVIVTANNAKRENIS-LWVRSRLLEGDIESLTDLRI-RGHYDVNSVWKVA 216 +L+ + T EN S L V + EG R+ R H S++ Sbjct: 454 VLMW-------EVFTEGKMPFENKSNLQVVEAISEG-------FRLYRPHLAPMSIY--- 496 Query: 215 EMALHCTEHKRQDRPTMMEVVEGLKE 138 E+ C K + RPT E++ + E Sbjct: 497 EVMYSCWHEKPEGRPTFAELLRAVTE 522
>PMK1_CAEEL (Q17446) Mitogen-activated protein kinase pmk-1 (EC 2.7.11.24) (p38| MAP kinase 1) (Stress-activated protein kinase pmk-1) Length = 377 Score = 39.3 bits (90), Expect = 0.008 Identities = 26/70 (37%), Positives = 35/70 (50%), Gaps = 1/70 (1%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTHATTRPMGTSGYLDPEYYAT-SHLSEKSDVYSFG 390 I + D E +I DFGL R SEM+ + TR Y PE H ++ DV+S G Sbjct: 167 IAVNEDCELKILDFGLARQTDSEMTGYVATR-----WYRAPEIMLNWMHYTQTVDVWSVG 221 Query: 389 ILLLVLITAQ 360 +L LIT + Sbjct: 222 CILAELITGK 231
>M3LK7_DROME (P83104) Putative mitogen-activated protein kinase kinase kinase| 7-like (EC 2.7.11.25) Length = 393 Score = 39.3 bits (90), Expect = 0.008 Identities = 25/62 (40%), Positives = 35/62 (56%) Frame = -2 Query: 545 EARISDFGLTRAFSSEMSTHATTRPMGTSGYLDPEYYATSHLSEKSDVYSFGILLLVLIT 366 + +I DFGL +++MS + T GT Y+ PE + K DVYSFGI+L L+T Sbjct: 147 DLKICDFGL----ATDMSNNKTDM-QGTLRYMAPEAIKHLKYTAKCDVYSFGIMLWELMT 201 Query: 365 AQ 360 Q Sbjct: 202 RQ 203
>SHK1_SCHPO (P50527) Serine/threonine-protein kinase pak1/shk1 (EC 2.7.11.1)| Length = 658 Score = 39.3 bits (90), Expect = 0.008 Identities = 21/76 (27%), Positives = 37/76 (48%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTHATTRPMGTSGYLDPEYYATSHLSEKSDVYSFGI 387 ILL+ + +++DFG S M+ T +GT ++ PE K DV+S GI Sbjct: 511 ILLSLQGDIKLTDFGFCAQIDSNMTKRTTM--VGTPYWMAPEVVTRKEYGFKVDVWSLGI 568 Query: 386 LLLVLITAQPVIVTAN 339 + + ++ +P + N Sbjct: 569 MAIEMVEGEPPYLNEN 584
>BLK_MOUSE (P16277) Tyrosine-protein kinase BLK (EC 2.7.10.2) (B lymphocyte| kinase) (p55-BLK) Length = 498 Score = 38.9 bits (89), Expect = 0.010 Identities = 24/68 (35%), Positives = 39/68 (57%), Gaps = 1/68 (1%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTHATTR-PMGTSGYLDPEYYATSHLSEKSDVYSFG 390 IL++ L +I+DFGL R SE + + P+ + PE + K+DV+SFG Sbjct: 359 ILVSETLCCKIADFGLARIIDSEYTAQEGAKFPIKWTA---PEAIHFGVFTIKADVWSFG 415 Query: 389 ILLLVLIT 366 +LL+V++T Sbjct: 416 VLLMVIVT 423
>CLA4_ASHGO (Q9HFW2) Serine/threonine-protein kinase CLA4 (EC 2.7.11.1)| Length = 793 Score = 38.9 bits (89), Expect = 0.010 Identities = 21/70 (30%), Positives = 35/70 (50%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTHATTRPMGTSGYLDPEYYATSHLSEKSDVYSFGI 387 +LL +I+DFG + + S AT +GT ++ PE EK DV+S GI Sbjct: 650 VLLDTHGRVKITDFGFCAKLTDKRSKRATM--VGTPYWMAPEVVKQREYDEKVDVWSLGI 707 Query: 386 LLLVLITAQP 357 + + ++ +P Sbjct: 708 MTIEMLEGEP 717
>HT1_ARATH (Q2MHE4) Serine/threonine-protein kinase HT1 (EC 2.7.11.1) (High| leaf temperature protein 1) Length = 390 Score = 38.9 bits (89), Expect = 0.010 Identities = 23/68 (33%), Positives = 34/68 (50%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTHATTRPMGTSGYLDPEYYATSHLSEKSDVYSFGI 387 +LL ++ +++DFG + E MGT ++ PE + K DVYSFGI Sbjct: 218 LLLNDEMRVKVADFGTS---CLETQCREAKGNMGTYRWMAPEMIKEKPYTRKVDVYSFGI 274 Query: 386 LLLVLITA 363 +L L TA Sbjct: 275 VLWELTTA 282
>NIMA_EMENI (P11837) G2-specific protein kinase nimA (EC 2.7.11.1) (Never in| mitosis) Length = 699 Score = 38.9 bits (89), Expect = 0.010 Identities = 41/156 (26%), Positives = 71/156 (45%), Gaps = 2/156 (1%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTHATTRPMGTSGYLDPEYYATSHLSEKSDVYSFGI 387 I L +D ++ DFGL++ S A+T +GT Y+ PE A + +SD+++ G Sbjct: 172 IFLGSDNTVKLGDFGLSKLMHSH--DFASTY-VGTPFYMSPEICAAEKYTLRSDIWAVGC 228 Query: 386 LLLVLITAQPVIVTANNAKRENISLWVRSRLLEGDIESLTDLRIRGHYDVNSVWKVAEMA 207 ++ L +P NA R +I L + R EG L D + + + V Sbjct: 229 IMYELCQREPPF----NA-RTHIQLVQKIR--EGKFAPLPD------FYSSELKNVIASC 275 Query: 206 LHCTEHKRQDRPTMME--VVEGLKEGLQLENSSRSS 105 L R D T++ V+ ++ ++L N SR++ Sbjct: 276 LRVNPDHRPDTATLINTPVIRLMRREVELNNLSRAA 311
>HCK_HUMAN (P08631) Tyrosine-protein kinase HCK (EC 2.7.10.2)| (p59-HCK/p60-HCK) (Hemopoietic cell kinase) Length = 525 Score = 38.9 bits (89), Expect = 0.010 Identities = 25/67 (37%), Positives = 35/67 (52%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTHATTRPMGTSGYLDPEYYATSHLSEKSDVYSFGI 387 IL++A L +I+DFGL R T A + PE + KSDV+SFGI Sbjct: 386 ILVSASLVCKIADFGLARVIEDNEYT-AREGAKFPIKWTAPEAINFGSFTIKSDVWSFGI 444 Query: 386 LLLVLIT 366 LL+ ++T Sbjct: 445 LLMEIVT 451
>EPHA6_RAT (P54758) Ephrin type-A receptor 6 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EHK-2) (EPH homology kinase 2) Length = 1035 Score = 38.9 bits (89), Expect = 0.010 Identities = 38/159 (23%), Positives = 70/159 (44%), Gaps = 3/159 (1%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSE-MSTHATTRPMGTSGYLDPEYYATSHLSEKSDVYSFG 390 IL+ ++L ++SDFGL+R + + + TT + PE A S SDV+S+G Sbjct: 803 ILVNSNLVCKVSDFGLSRVLEDDPEAAYTTTGGKIPIRWTAPEAIAYRKFSSASDVWSYG 862 Query: 389 ILLLVLIT--AQPVIVTANNAKRENISLWVRSRLLEGDIESLTDLRIRGHYDVNSVWKVA 216 I++ +++ +P +N +I R G SL Sbjct: 863 IVMWEVMSYGERPYWEMSNQDVILSIEEGYRLPAPMGCPPSL-----------------H 905 Query: 215 EMALHCTEHKRQDRPTMMEVVEGLKEGLQLENSSRSSVE 99 ++ LHC + +R RP ++V L + ++ ++ + VE Sbjct: 906 QLMLHCWQKERNHRPKFTDIVSFLDKLIRNPSALHTLVE 944
>NEK7_MOUSE (Q9ES74) Serine/threonine-protein kinase Nek7 (EC 2.7.11.1)| (NimA-related protein kinase 7) Length = 302 Score = 38.9 bits (89), Expect = 0.010 Identities = 24/69 (34%), Positives = 36/69 (52%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTHATTRPMGTSGYLDPEYYATSHLSEKSDVYSFGI 387 + +TA ++ D GL R FSS+ T A +GT Y+ PE + + KSD++S G Sbjct: 167 VFITATGVVKLGDLGLGRFFSSK--TTAAHSLVGTPYYMSPERIHENGYNFKSDIWSLGC 224 Query: 386 LLLVLITAQ 360 LL + Q Sbjct: 225 LLYEMAALQ 233
>NEK7_HUMAN (Q8TDX7) Serine/threonine-protein kinase Nek7 (EC 2.7.11.1)| (NimA-related protein kinase 7) Length = 302 Score = 38.9 bits (89), Expect = 0.010 Identities = 24/69 (34%), Positives = 36/69 (52%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTHATTRPMGTSGYLDPEYYATSHLSEKSDVYSFGI 387 + +TA ++ D GL R FSS+ T A +GT Y+ PE + + KSD++S G Sbjct: 167 VFITATGVVKLGDLGLGRFFSSK--TTAAHSLVGTPYYMSPERIHENGYNFKSDIWSLGC 224 Query: 386 LLLVLITAQ 360 LL + Q Sbjct: 225 LLYEMAALQ 233
>EPHA3_MOUSE (P29319) Ephrin type-A receptor 3 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor ETK1) (MEK4) Length = 983 Score = 38.9 bits (89), Expect = 0.010 Identities = 34/144 (23%), Positives = 64/144 (44%), Gaps = 6/144 (4%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTHATTR----PMGTSGYLDPEYYATSHLSEKSDVY 399 IL+ ++L ++SDFGL+R + TTR P+ + PE + + SDV+ Sbjct: 752 ILINSNLVCKVSDFGLSRVLEDDPEAAYTTRGGKIPI---RWTSPEAMSYRKFTSASDVW 808 Query: 398 SFGILLLVLIT--AQPVIVTANNAKRENISLWVRSRLLEGDIESLTDLRIRGHYDVNSVW 225 S+GI+L +++ +P S++ D+ D R R ++ Sbjct: 809 SYGIVLWEVMSYGERPY-----------------SQMSNQDVIKAVDERYRLPPPMDCPA 851 Query: 224 KVAEMALHCTEHKRQDRPTMMEVV 153 + ++ L C + R +RP ++V Sbjct: 852 ALYQLMLDCWQKDRNNRPKFEQIV 875
>SPKA_SYNY3 (Q9FAB3) Serine/threonine-protein kinase A (EC 2.7.11.1)| Length = 521 Score = 38.9 bits (89), Expect = 0.010 Identities = 19/69 (27%), Positives = 35/69 (50%) Frame = -2 Query: 539 RISDFGLTRAFSSEMSTHATTRPMGTSGYLDPEYYATSHLSEKSDVYSFGILLLVLITAQ 360 +I DFG+ + + + T MGT Y PE L +SD+YS G+++ ++T + Sbjct: 167 KILDFGIAKLVQAAEESK-TQAFMGTLAYCSPEQMEGKELDSRSDIYSLGVMMYEMLTGE 225 Query: 359 PVIVTANNA 333 + N++ Sbjct: 226 MPLFPDNSS 234
>CDC15_YEAST (P27636) Cell division control protein 15 (EC 2.7.11.1)| Length = 974 Score = 38.9 bits (89), Expect = 0.010 Identities = 22/70 (31%), Positives = 37/70 (52%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTHATTRPMGTSGYLDPEYYATSHLSEKSDVYSFGI 387 ILL+AD +++DFG++ +S T A GT ++ PE S SD++S G Sbjct: 152 ILLSADNTVKLADFGVSTIVNSSALTLA-----GTLNWMAPEILGNRGASTLSDIWSLGA 206 Query: 386 LLLVLITAQP 357 ++ ++T P Sbjct: 207 TVVEMLTKNP 216
>PKN2_CORGL (Q8NU97) Serine/threonine protein kinases pknA (EC 2.7.11.1)| Length = 469 Score = 38.9 bits (89), Expect = 0.010 Identities = 20/61 (32%), Positives = 37/61 (60%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTHATTRPMGTSGYLDPEYYATSHLSEKSDVYSFGI 387 +L+TA+ +I+DFG+ +A ++ T T +GT+ Y+ PE ++ SD+YS G+ Sbjct: 154 MLITANGIVKITDFGIAKAAAAVPLTR-TGMVVGTAQYVSPEQAQGKEVTAASDIYSLGV 212 Query: 386 L 384 + Sbjct: 213 V 213
>MEK2_CAEEL (Q10664) Dual specificity mitogen-activated protein kinase kinase| mek-2 (EC 2.7.12.2) (MAP kinase kinase mek-2) Length = 387 Score = 38.9 bits (89), Expect = 0.010 Identities = 21/79 (26%), Positives = 42/79 (53%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTHATTRPMGTSGYLDPEYYATSHLSEKSDVYSFGI 387 +L+ ++ E ++ DFG++ M+ +GT Y+ PE SH + SD++SFG+ Sbjct: 201 MLVNSNGEIKLCDFGVSGMLIDSMANSF----VGTRSYMAPERLTGSHYTISSDIWSFGL 256 Query: 386 LLLVLITAQPVIVTANNAK 330 L+ L+ + + + A+ Sbjct: 257 SLVELLIGRYPVPAPSQAE 275
>PKN3_MYXXA (Q9XBQ0) Serine/threonine-protein kinase pkn3 (EC 2.7.11.1)| Length = 547 Score = 38.5 bits (88), Expect = 0.013 Identities = 21/61 (34%), Positives = 32/61 (52%), Gaps = 3/61 (4%) Frame = -2 Query: 539 RISDFGLTRAFSSEMSTHATTRP---MGTSGYLDPEYYATSHLSEKSDVYSFGILLLVLI 369 ++ DFG+ + S A TR GT Y+ PE S L +SD+Y+ G++L L+ Sbjct: 161 KVLDFGIAKITDSTDDGPALTRAGFVCGTPEYMSPEQARGSQLDHRSDLYAVGVILYQLM 220 Query: 368 T 366 T Sbjct: 221 T 221
>KPK19_ARATH (Q39030) Serine/threonine-protein kinase AtPK19 (EC 2.7.11.1)| (Ribosomal-protein S6 kinase homolog) Length = 471 Score = 38.5 bits (88), Expect = 0.013 Identities = 22/83 (26%), Positives = 41/83 (49%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTHATTRPMGTSGYLDPEYYATSHLSEKSDVYSFGI 387 IL+ D ++DFGL + F +++ GT+ Y+ PE + +D +S GI Sbjct: 269 ILMDVDGHVMLTDFGLAKEFEENTRSNSMC---GTTEYMAPEIVRGKGHDKAADWWSVGI 325 Query: 386 LLLVLITAQPVIVTANNAKRENI 318 LL ++T +P + + ++ I Sbjct: 326 LLYEMLTGKPPFLGSKGKIQQKI 348
>NIM1_NEUCR (P48479) G2-specific protein kinase nim-1 (EC 2.7.11.1)| Length = 779 Score = 38.5 bits (88), Expect = 0.013 Identities = 22/70 (31%), Positives = 36/70 (51%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTHATTRPMGTSGYLDPEYYATSHLSEKSDVYSFGI 387 + L D ++ DFGL++ S A+T +GT Y+ PE A + KSD++S G Sbjct: 167 VFLGEDNSVKLGDFGLSKVMQSH--DFASTY-VGTPFYMSPEICAAEKYTLKSDIWSLGC 223 Query: 386 LLLVLITAQP 357 ++ L +P Sbjct: 224 IIYELCAREP 233
>PKN2_MYXXA (P54736) Serine/threonine-protein kinase pkn2 (EC 2.7.11.1)| Length = 830 Score = 38.5 bits (88), Expect = 0.013 Identities = 19/56 (33%), Positives = 32/56 (57%), Gaps = 2/56 (3%) Frame = -2 Query: 545 EARISDFGLTRAFSSEMSTHATTRP--MGTSGYLDPEYYATSHLSEKSDVYSFGIL 384 +AR+ DFG+ R + ++ + +GT YL PE + + +SD+YSFG+L Sbjct: 151 QARLLDFGIARLVEPDAASSVSQIGVVLGTPEYLSPEQAVGAKVDTRSDLYSFGVL 206
>HCK_RAT (P50545) Tyrosine-protein kinase HCK (EC 2.7.10.2) (p56-HCK)| (Hemopoietic cell kinase) Length = 502 Score = 38.5 bits (88), Expect = 0.013 Identities = 25/67 (37%), Positives = 35/67 (52%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTHATTRPMGTSGYLDPEYYATSHLSEKSDVYSFGI 387 IL++A L +I+DFGL R T A + PE + KSDV+SFGI Sbjct: 363 ILVSASLVCKIADFGLARIIEDNEYT-AREGAKFPIKWTAPEAINFGSFTIKSDVWSFGI 421 Query: 386 LLLVLIT 366 LL+ ++T Sbjct: 422 LLMEIVT 428
>E2AK3_HUMAN (Q9NZJ5) Eukaryotic translation initiation factor 2-alpha kinase 3| precursor (EC 2.7.11.1) (PRKR-like endoplasmic reticulum kinase) (Pancreatic eIF2-alpha kinase) (HsPEK) Length = 1115 Score = 38.5 bits (88), Expect = 0.013 Identities = 22/76 (28%), Positives = 32/76 (42%), Gaps = 10/76 (13%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTHATTRPM----------GTSGYLDPEYYATSHLS 417 I T D ++ DFGL A + PM GT Y+ PE + S Sbjct: 942 IFFTMDDVVKVGDFGLVTAMDQDEEEQTVLTPMPAYARHTGQVGTKLYMSPEQIHGNSYS 1001 Query: 416 EKSDVYSFGILLLVLI 369 K D++S G++L L+ Sbjct: 1002 HKVDIFSLGLILFELL 1017
>KS6A_CAEEL (Q21734) Putative ribosomal protein S6 kinase alpha (EC 2.7.11.1)| Length = 784 Score = 38.5 bits (88), Expect = 0.013 Identities = 24/68 (35%), Positives = 38/68 (55%), Gaps = 1/68 (1%) Frame = -2 Query: 566 ILLTADLEARISDFGLTR-AFSSEMSTHATTRPMGTSGYLDPEYYATSHLSEKSDVYSFG 390 ILL AD +++DFGL++ A SE T++ GT Y+ PE S +D +S G Sbjct: 235 ILLDADGHIKVTDFGLSKEAIDSEKKTYSF---CGTVEYMAPEVINRRGHSMAADFWSLG 291 Query: 389 ILLLVLIT 366 +L+ ++T Sbjct: 292 VLMFEMLT 299 Score = 30.0 bits (66), Expect = 4.8 Identities = 18/58 (31%), Positives = 27/58 (46%) Frame = -2 Query: 539 RISDFGLTRAFSSEMSTHATTRPMGTSGYLDPEYYATSHLSEKSDVYSFGILLLVLIT 366 RI DFG + +E T P T+ ++ PE DV+S G+LL ++T Sbjct: 591 RIVDFGFAKQSRAENGMLMT--PCYTAQFVAPEVLRKQGYDRSCDVWSLGVLLHTMLT 646
>EPHA4_HUMAN (P54764) Ephrin type-A receptor 4 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor SEK) (Receptor protein-tyrosine kinase HEK8) Length = 986 Score = 38.5 bits (88), Expect = 0.013 Identities = 41/166 (24%), Positives = 74/166 (44%), Gaps = 7/166 (4%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTHATTR----PMGTSGYLDPEYYATSHLSEKSDVY 399 IL+ ++L ++SDFG++R + TTR P+ + PE A + SDV+ Sbjct: 752 ILVNSNLVCKVSDFGMSRVLEDDPEAAYTTRGGKIPI---RWTAPEAIAYRKFTSASDVW 808 Query: 398 SFGILLLVLIT--AQPVIVTANNAKRENISLWVRSRLLEGDIESLTDLRIRGHYDVNSVW 225 S+GI++ +++ +P +N + I R + D I H Sbjct: 809 SYGIVMWEVMSYGERPYWDMSNQDVIKAIEEGYR-------LPPPMDCPIALH------- 854 Query: 224 KVAEMALHCTEHKRQDRPTMMEVVEGLKEGLQLENS-SRSSVETGR 90 ++ L C + +R DRP ++V L + ++ NS R+ E+ R Sbjct: 855 ---QLMLDCWQKERSDRPKFGQIVNMLDKLIRNPNSLKRTGTESSR 897
>KIN16_CAEEL (P34892) Receptor-like tyrosine-protein kinase kin-16 precursor (EC| 2.7.10.1) Length = 495 Score = 38.5 bits (88), Expect = 0.013 Identities = 24/72 (33%), Positives = 37/72 (51%), Gaps = 5/72 (6%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSE-----MSTHATTRPMGTSGYLDPEYYATSHLSEKSDV 402 +LL + RI+DFG+ R ++ T P+ ++ PE + T +EKSDV Sbjct: 327 VLLKKNKTIRIADFGMARTHENKSYYIPQKTKDAPVPVR---WMSPEAFDTMKFTEKSDV 383 Query: 401 YSFGILLLVLIT 366 +SFGI L + T Sbjct: 384 WSFGICLYEIFT 395
>KPK1_ARATH (P42818) Serine/threonine-protein kinase AtPK1/AtPK6 (EC 2.7.11.1)| Length = 465 Score = 38.5 bits (88), Expect = 0.013 Identities = 22/83 (26%), Positives = 41/83 (49%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTHATTRPMGTSGYLDPEYYATSHLSEKSDVYSFGI 387 IL+ D ++DFGL + F +++ GT+ Y+ PE + +D +S GI Sbjct: 263 ILMDTDGHVMLTDFGLAKEFEENTRSNSMC---GTTEYMAPEIVRGKGHDKAADWWSVGI 319 Query: 386 LLLVLITAQPVIVTANNAKRENI 318 LL ++T +P + + ++ I Sbjct: 320 LLYEMLTGKPPFLGSKGKIQQKI 342
>RCK2_YEAST (P38623) Serine/threonine-protein kinase RCK2 (EC 2.7.11.1) (CAM| kinase-like protein kinase CLK1) Length = 610 Score = 38.5 bits (88), Expect = 0.013 Identities = 20/61 (32%), Positives = 31/61 (50%) Frame = -2 Query: 539 RISDFGLTRAFSSEMSTHATTRPMGTSGYLDPEYYATSHLSEKSDVYSFGILLLVLITAQ 360 +++DFGL++ S+ T P GT GY PE H S K D++ G +L ++ Sbjct: 362 KLADFGLSKQIFSKN----TKTPCGTVGYTAPEVVKDEHYSMKVDMWGIGCVLYTMLCGF 417 Query: 359 P 357 P Sbjct: 418 P 418
>HCK_MOUSE (P08103) Tyrosine-protein kinase HCK (EC 2.7.10.2)| (p56-HCK/p59-HCK) (Hemopoietic cell kinase) (B-cell/myeloid kinase) (BMK) Length = 523 Score = 38.5 bits (88), Expect = 0.013 Identities = 25/67 (37%), Positives = 35/67 (52%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTHATTRPMGTSGYLDPEYYATSHLSEKSDVYSFGI 387 IL++A L +I+DFGL R T A + PE + KSDV+SFGI Sbjct: 384 ILVSASLVCKIADFGLARIIEDNEYT-AREGAKFPIKWTAPEAINFGSFTIKSDVWSFGI 442 Query: 386 LLLVLIT 366 LL+ ++T Sbjct: 443 LLMEIVT 449
>ARK1_SCHPO (O59790) Serine/threonine-protein kinase ark1 (EC 2.7.11.1)| (Aurora-related kinase 1) Length = 355 Score = 38.5 bits (88), Expect = 0.013 Identities = 24/70 (34%), Positives = 34/70 (48%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTHATTRPMGTSGYLDPEYYATSHLSEKSDVYSFGI 387 ILL D E ++SDFG +S ++ T GT YL PE +EK D++S G+ Sbjct: 218 ILLGIDGEIKLSDFG----WSVHAPSNRRTTLCGTLDYLPPEMVEGKEHTEKVDLWSLGV 273 Query: 386 LLLVLITAQP 357 L + P Sbjct: 274 LTYEFLVGAP 283
>SRMS_MOUSE (Q62270) Tyrosine-protein kinase Srms (EC 2.7.10.2) (PTK70)| Length = 496 Score = 38.1 bits (87), Expect = 0.017 Identities = 22/67 (32%), Positives = 37/67 (55%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTHATTRPMGTSGYLDPEYYATSHLSEKSDVYSFGI 387 +L+ DL +++DFGL R ++ + ++ + + PE S+KSDV+SFGI Sbjct: 360 VLVGDDLTCKVADFGLARLLKDDVYSPSSGSKIPVK-WTAPEAANYRVFSQKSDVWSFGI 418 Query: 386 LLLVLIT 366 LL + T Sbjct: 419 LLYEVFT 425
>KSYK_HUMAN (P43405) Tyrosine-protein kinase SYK (EC 2.7.10.2) (Spleen tyrosine| kinase) Length = 635 Score = 38.1 bits (87), Expect = 0.017 Identities = 23/63 (36%), Positives = 35/63 (55%), Gaps = 1/63 (1%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTH-ATTRPMGTSGYLDPEYYATSHLSEKSDVYSFG 390 +LL A+ISDFGL++A ++ + + A T + PE S KSDV+SFG Sbjct: 500 VLLVTQHYAKISDFGLSKALRADENYYKAQTHGKWPVKWYAPECINYYKFSSKSDVWSFG 559 Query: 389 ILL 381 +L+ Sbjct: 560 VLM 562
>KIN15_CAEEL (P34891) Receptor-like tyrosine-protein kinase kin-15 precursor (EC| 2.7.10.1) Length = 488 Score = 38.1 bits (87), Expect = 0.017 Identities = 22/65 (33%), Positives = 37/65 (56%), Gaps = 3/65 (4%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTHATTRPMGT---SGYLDPEYYATSHLSEKSDVYS 396 +LL + RI+DFGL R + + + T+ +GT + ++ PE +EKSDV+S Sbjct: 325 VLLNKNKTIRIADFGLARKYQVD-GYYRITKGVGTPMPARWMAPEVMREGKCTEKSDVWS 383 Query: 395 FGILL 381 +G+ L Sbjct: 384 YGVSL 388
>PKWA_THECU (P49695) Probable serine/threonine-protein kinase pkwA (EC| 2.7.11.1) Length = 742 Score = 38.1 bits (87), Expect = 0.017 Identities = 24/69 (34%), Positives = 35/69 (50%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTHATTRPMGTSGYLDPEYYATSHLSEKSDVYSFGI 387 I+L AD R+ DFG+ R S + T + +GT Y+ PE S + SDV+S G Sbjct: 144 IVLAAD-GPRVIDFGVARPLDSSVMTQSGA-VIGTLAYMSPEQTDGSQVGPASDVFSLGT 201 Query: 386 LLLVLITAQ 360 +L T + Sbjct: 202 VLAFAATGR 210
>DAF4_CAEEL (P50488) Cell-surface receptor daf-4 precursor (EC 2.7.11.30)| (Abnormal dauer formation protein 4) Length = 744 Score = 38.1 bits (87), Expect = 0.017 Identities = 22/72 (30%), Positives = 37/72 (51%), Gaps = 5/72 (6%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTHATTRPMGTSGYLDPEYYA-----TSHLSEKSDV 402 IL+ +D+ I+DFGL R +S ++ +GT Y+ PE T + DV Sbjct: 446 ILVKSDMTTCIADFGLARIYSYDIEQSDLLGQVGTKRYMSPEMLEGATEFTPTAFKAMDV 505 Query: 401 YSFGILLLVLIT 366 YS G+++ +I+ Sbjct: 506 YSMGLVMWEVIS 517
>PAK4_HUMAN (O96013) Serine/threonine-protein kinase PAK 4 (EC 2.7.11.1)| (p21-activated kinase 4) (PAK-4) Length = 591 Score = 38.1 bits (87), Expect = 0.017 Identities = 20/70 (28%), Positives = 37/70 (52%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTHATTRPMGTSGYLDPEYYATSHLSEKSDVYSFGI 387 ILLT D ++SDFG S E+ + +GT ++ PE + + D++S GI Sbjct: 446 ILLTHDGRVKLSDFGFCAQVSKEVPRRKSL--VGTPYWMAPELISRLPYGPEVDIWSLGI 503 Query: 386 LLLVLITAQP 357 +++ ++ +P Sbjct: 504 MVIEMVDGEP 513
>KOK0_YEAST (Q12236) Probable serine/threonine-protein kinase YOL100W (EC| 2.7.11.1) Length = 1081 Score = 38.1 bits (87), Expect = 0.017 Identities = 22/85 (25%), Positives = 42/85 (49%), Gaps = 9/85 (10%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFS------SEMSTHATTRP---MGTSGYLDPEYYATSHLSE 414 ILL +++ +++DFG + + S+ +TR +GT+ Y+ PE S Sbjct: 309 ILLDGEMKIKLTDFGTAKLLNPTNNSVSKPEYDLSTRSKSFVGTAEYVSPELLNDSFTDY 368 Query: 413 KSDVYSFGILLLVLITAQPVIVTAN 339 + D+++FG +L +I +P N Sbjct: 369 RCDIWAFGCILFQMIAGKPPFKATN 393
>EPHA3_HUMAN (P29320) Ephrin type-A receptor 3 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor ETK1) (HEK) (HEK4) Length = 983 Score = 38.1 bits (87), Expect = 0.017 Identities = 23/66 (34%), Positives = 36/66 (54%), Gaps = 4/66 (6%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTHATTR----PMGTSGYLDPEYYATSHLSEKSDVY 399 IL+ ++L ++SDFGL+R + TTR P+ + PE A + SDV+ Sbjct: 752 ILINSNLVCKVSDFGLSRVLEDDPEAAYTTRGGKIPI---RWTSPEAIAYRKFTSASDVW 808 Query: 398 SFGILL 381 S+GI+L Sbjct: 809 SYGIVL 814
>STE20_YEAST (Q03497) Serine/threonine-protein kinase STE20 (EC 2.7.11.1)| Length = 939 Score = 38.1 bits (87), Expect = 0.017 Identities = 21/70 (30%), Positives = 41/70 (58%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTHATTRPMGTSGYLDPEYYATSHLSEKSDVYSFGI 387 ILL+ + + +++DFG A +E++ TT +GT ++ PE + K D++S GI Sbjct: 745 ILLSMEGDIKLTDFGFC-AQINELNLKRTTM-VGTPYWMAPEVVSRKEYGPKVDIWSLGI 802 Query: 386 LLLVLITAQP 357 +++ +I +P Sbjct: 803 MIIEMIEGEP 812
>KSYK_RAT (Q64725) Tyrosine-protein kinase SYK (EC 2.7.10.2) (Spleen tyrosine| kinase) Length = 629 Score = 38.1 bits (87), Expect = 0.017 Identities = 23/63 (36%), Positives = 35/63 (55%), Gaps = 1/63 (1%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTH-ATTRPMGTSGYLDPEYYATSHLSEKSDVYSFG 390 +LL A+ISDFGL++A ++ + + A T + PE S KSDV+SFG Sbjct: 494 VLLVTQHYAKISDFGLSKALRADENYYKAQTHGKWPVKWYAPECINYFKFSSKSDVWSFG 553 Query: 389 ILL 381 +L+ Sbjct: 554 VLM 556
>KSYK_MOUSE (P48025) Tyrosine-protein kinase SYK (EC 2.7.10.2) (Spleen tyrosine| kinase) Length = 629 Score = 38.1 bits (87), Expect = 0.017 Identities = 23/63 (36%), Positives = 35/63 (55%), Gaps = 1/63 (1%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTH-ATTRPMGTSGYLDPEYYATSHLSEKSDVYSFG 390 +LL A+ISDFGL++A ++ + + A T + PE S KSDV+SFG Sbjct: 494 VLLVTQHYAKISDFGLSKALRADENYYKAQTHGKWPVKWYAPECINYYKFSSKSDVWSFG 553 Query: 389 ILL 381 +L+ Sbjct: 554 VLM 556
>KPCA_MOUSE (P20444) Protein kinase C alpha type (EC 2.7.11.13) (PKC-alpha)| (PKC-A) Length = 671 Score = 38.1 bits (87), Expect = 0.017 Identities = 21/71 (29%), Positives = 37/71 (52%), Gaps = 1/71 (1%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTHATTRPM-GTSGYLDPEYYATSHLSEKSDVYSFG 390 ++L ++ +I+DFG+ + M TTR GT Y+ PE A + D +++G Sbjct: 468 VMLNSEGHIKIADFGMCK---EHMMDGVTTRTFCGTPDYIAPEIIAYQPYGKSVDWWAYG 524 Query: 389 ILLLVLITAQP 357 +LL ++ QP Sbjct: 525 VLLYEMLAGQP 535
>KSYK_PIG (Q00655) Tyrosine-protein kinase SYK (EC 2.7.10.2) (Spleen tyrosine| kinase) [Contains: 72 kDa tyrosine-protein kinase SYK; 40 kDa tyrosine-protein kinase SYK] Length = 628 Score = 38.1 bits (87), Expect = 0.017 Identities = 23/63 (36%), Positives = 35/63 (55%), Gaps = 1/63 (1%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTH-ATTRPMGTSGYLDPEYYATSHLSEKSDVYSFG 390 +LL A+ISDFGL++A ++ + + A T + PE S KSDV+SFG Sbjct: 493 VLLVTQHYAKISDFGLSKALRADENYYKAQTHGKWPVKWYAPECINYYKFSSKSDVWSFG 552 Query: 389 ILL 381 +L+ Sbjct: 553 VLM 555
>KIN3_YEAST (P22209) Serine/threonine-protein kinase KIN3 (EC 2.7.11.1)| Length = 435 Score = 38.1 bits (87), Expect = 0.017 Identities = 29/105 (27%), Positives = 46/105 (43%), Gaps = 9/105 (8%) Frame = -2 Query: 539 RISDFGLTRAFSSEMSTHATTRPMGTSGYLDPEYYATSHLSEKSDVYSFGILLLVLITAQ 360 ++ DFGL + S E S T +GT Y+ PE S SD++S G ++ + + Sbjct: 228 KLGDFGLAK--SLETSIQFATTYVGTPYYMSPEVLMDQPYSPLSDIWSLGCVIFEMCSLH 285 Query: 359 PVIVTAN---------NAKRENISLWVRSRLLEGDIESLTDLRIR 252 P N N K + + + SR L I S+ D+ +R Sbjct: 286 PPFQAKNYLELQTKIKNGKCDTVPEYY-SRGLNAIIHSMIDVNLR 329
>STE20_CANAL (Q92212) Serine/threonine-protein kinase STE20 homolog (EC 2.7.11.1)| Length = 1230 Score = 37.7 bits (86), Expect = 0.023 Identities = 21/70 (30%), Positives = 35/70 (50%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTHATTRPMGTSGYLDPEYYATSHLSEKSDVYSFGI 387 ILL D +I+DFG + S T +GT ++ PE + K DV+S GI Sbjct: 1079 ILLNMDGNIKITDFGFCAQINEINSKRITM--VGTPYWMAPEIVSRKEYGPKVDVWSLGI 1136 Query: 386 LLLVLITAQP 357 +++ ++ +P Sbjct: 1137 MIIEMLEGEP 1146
>PAK4_MOUSE (Q8BTW9) Serine/threonine-protein kinase PAK 4 (EC 2.7.11.1)| (p21-activated kinase 4) (PAK-4) Length = 593 Score = 37.7 bits (86), Expect = 0.023 Identities = 19/70 (27%), Positives = 37/70 (52%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTHATTRPMGTSGYLDPEYYATSHLSEKSDVYSFGI 387 ILLT D ++SDFG S E+ + +GT ++ PE + + D++S G+ Sbjct: 448 ILLTHDGRVKLSDFGFCAQVSKEVPRRKSL--VGTPYWMAPELISRLPYGPEVDIWSLGV 505 Query: 386 LLLVLITAQP 357 +++ ++ +P Sbjct: 506 MVIEMVDGEP 515
>PAK2_RAT (Q64303) Serine/threonine-protein kinase PAK 2 (EC 2.7.11.1)| (p21-activated kinase 2) (PAK-2) (Gamma-PAK) (p62-PAK) Length = 524 Score = 37.7 bits (86), Expect = 0.023 Identities = 19/76 (25%), Positives = 37/76 (48%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTHATTRPMGTSGYLDPEYYATSHLSEKSDVYSFGI 387 +LL + +++DFG + E S +T +GT ++ PE K D++S GI Sbjct: 374 VLLGMEGSVKLTDFGFCAQITPEQSKRSTM--VGTPYWMAPEVVTRKAYGPKVDIWSLGI 431 Query: 386 LLLVLITAQPVIVTAN 339 + + ++ +P + N Sbjct: 432 MAIEMVEGEPPYLNEN 447
>PAK2_RABIT (Q29502) Serine/threonine-protein kinase PAK 2 (EC 2.7.11.1)| (p21-activated kinase 2) (PAK-2) (Gamma-PAK) (p21-activated protein kinase I) (PAKI) Length = 524 Score = 37.7 bits (86), Expect = 0.023 Identities = 19/76 (25%), Positives = 37/76 (48%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTHATTRPMGTSGYLDPEYYATSHLSEKSDVYSFGI 387 +LL + +++DFG + E S +T +GT ++ PE K D++S GI Sbjct: 374 VLLGMEGSVKLTDFGFCAQITPEQSKRSTM--VGTPYWMAPEVVTRKAYGPKVDIWSLGI 431 Query: 386 LLLVLITAQPVIVTAN 339 + + ++ +P + N Sbjct: 432 MAIEMVEGEPPYLNEN 447
>PAK2_MOUSE (Q8CIN4) Serine/threonine-protein kinase PAK 2 (EC 2.7.11.1)| (p21-activated kinase 2) (PAK-2) Length = 524 Score = 37.7 bits (86), Expect = 0.023 Identities = 19/76 (25%), Positives = 37/76 (48%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTHATTRPMGTSGYLDPEYYATSHLSEKSDVYSFGI 387 +LL + +++DFG + E S +T +GT ++ PE K D++S GI Sbjct: 374 VLLGMEGSVKLTDFGFCAQITPEQSKRSTM--VGTPYWMAPEVVTRKAYGPKVDIWSLGI 431 Query: 386 LLLVLITAQPVIVTAN 339 + + ++ +P + N Sbjct: 432 MAIEMVEGEPPYLNEN 447
>PAK2_HUMAN (Q13177) Serine/threonine-protein kinase PAK 2 (EC 2.7.11.1)| (p21-activated kinase 2) (PAK-2) (PAK65) (Gamma-PAK) (S6/H4 kinase) Length = 524 Score = 37.7 bits (86), Expect = 0.023 Identities = 19/76 (25%), Positives = 37/76 (48%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTHATTRPMGTSGYLDPEYYATSHLSEKSDVYSFGI 387 +LL + +++DFG + E S +T +GT ++ PE K D++S GI Sbjct: 374 VLLGMEGSVKLTDFGFCAQITPEQSKRSTM--VGTPYWMAPEVVTRKAYGPKVDIWSLGI 431 Query: 386 LLLVLITAQPVIVTAN 339 + + ++ +P + N Sbjct: 432 MAIEMVEGEPPYLNEN 447
>CHK1_SCHPO (P34208) Serine/threonine-protein kinase chk1 (EC 2.7.11.1)| (Checkpoint kinase 1) Length = 496 Score = 37.7 bits (86), Expect = 0.023 Identities = 23/66 (34%), Positives = 33/66 (50%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTHATTRPMGTSGYLDPEYYATSHLSEKSDVYSFGI 387 ILL + +ISDFG FS + + P+G+ Y PE + K DV+S GI Sbjct: 143 ILLDYNGNLKISDFGFASLFSYKGKSRLLNSPVGSPPYAAPE-ITQQYDGSKVDVWSCGI 201 Query: 386 LLLVLI 369 +L L+ Sbjct: 202 ILFALL 207
>PKPA_PHYBL (Q01577) Serine/threonine-protein kinase pkpA (EC 2.7.11.1)| Length = 613 Score = 37.7 bits (86), Expect = 0.023 Identities = 20/62 (32%), Positives = 32/62 (51%) Frame = -2 Query: 545 EARISDFGLTRAFSSEMSTHATTRPMGTSGYLDPEYYATSHLSEKSDVYSFGILLLVLIT 366 E +I D G ++EM +GT ++ PE Y +EK D+Y+FG+ LL + T Sbjct: 154 EIKIGDMG-----TAEMKNGKKYTVIGTPEFMAPEMYEEQGYNEKVDIYAFGMCLLEMAT 208 Query: 365 AQ 360 + Sbjct: 209 GE 210
>MATK_HUMAN (P42679) Megakaryocyte-associated tyrosine-protein kinase (EC| 2.7.10.2) (Tyrosine-protein kinase CTK) (Protein kinase HYL) (Hematopoietic consensus tyrosine-lacking kinase) Length = 507 Score = 37.7 bits (86), Expect = 0.023 Identities = 23/62 (37%), Positives = 35/62 (56%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTHATTRPMGTSGYLDPEYYATSHLSEKSDVYSFGI 387 IL++ DL A++SDFGL +A ++ P+ + PE + KSDV+SFG+ Sbjct: 358 ILVSEDLVAKVSDFGLAKA--ERKGLDSSRLPV---KWTAPEALKHGKFTSKSDVWSFGV 412 Query: 386 LL 381 LL Sbjct: 413 LL 414
>HCK_MACFA (Q95M30) Tyrosine-protein kinase HCK (EC 2.7.10.2) (p56-HCK)| (Hemopoietic cell kinase) Length = 503 Score = 37.7 bits (86), Expect = 0.023 Identities = 25/67 (37%), Positives = 35/67 (52%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTHATTRPMGTSGYLDPEYYATSHLSEKSDVYSFGI 387 IL++A L +I+DFGL R T A + PE + KSDV+SFGI Sbjct: 364 ILVSASLVCKIADFGLARIIEDNEYT-AREGAKFPIKWTAPEAINFGSSTIKSDVWSFGI 422 Query: 386 LLLVLIT 366 LL+ ++T Sbjct: 423 LLMEIVT 429
>EPHA3_RAT (O08680) Ephrin type-A receptor 3 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor REK4) (TYRO-4) Length = 984 Score = 37.7 bits (86), Expect = 0.023 Identities = 23/66 (34%), Positives = 36/66 (54%), Gaps = 4/66 (6%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTHATTR----PMGTSGYLDPEYYATSHLSEKSDVY 399 IL+ ++L ++SDFGL+R + TTR P+ + PE A + SDV+ Sbjct: 753 ILINSNLVCKVSDFGLSRVLEDDPEAAYTTRGGKIPV---RWTSPEATAYRKFTSASDVW 809 Query: 398 SFGILL 381 S+GI+L Sbjct: 810 SYGIVL 815
>KPC2_DROME (P13677) Protein kinase C, eye isozyme (EC 2.7.11.13) (PKC)| (dPKC53E(EY)) (Protein INAC) (Inactivation no after-potential C protein) (Photoreceptor-specific PKC) (Eye-PKC) Length = 700 Score = 37.7 bits (86), Expect = 0.023 Identities = 23/69 (33%), Positives = 35/69 (50%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTHATTRPMGTSGYLDPEYYATSHLSEKSDVYSFGI 387 ILL + ++ DFGL++ +E T T GT Y+ PE + S +D +SFG+ Sbjct: 501 ILLDGEGHVKLVDFGLSKEGVTERQTTRTF--CGTPNYMAPEIVSYDPYSIAADWWSFGV 558 Query: 386 LLLVLITAQ 360 LL + Q Sbjct: 559 LLFEFMAGQ 567
>EPHA6_MOUSE (Q62413) Ephrin type-A receptor 6 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EHK-2) (EPH homology kinase 2) Length = 1035 Score = 37.7 bits (86), Expect = 0.023 Identities = 37/159 (23%), Positives = 69/159 (43%), Gaps = 3/159 (1%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSE-MSTHATTRPMGTSGYLDPEYYATSHLSEKSDVYSFG 390 IL+ ++L ++SDFGL+R + + + TT + PE A S SD +S+G Sbjct: 803 ILVNSNLVCKVSDFGLSRVLEDDPEAAYTTTGGKIPIRWTAPEAIAYRKFSSASDAWSYG 862 Query: 389 ILLLVLIT--AQPVIVTANNAKRENISLWVRSRLLEGDIESLTDLRIRGHYDVNSVWKVA 216 I++ +++ +P +N +I R G SL Sbjct: 863 IVMWEVMSYGERPYWEMSNQDVILSIEEGYRLPAPMGCPPSL-----------------Q 905 Query: 215 EMALHCTEHKRQDRPTMMEVVEGLKEGLQLENSSRSSVE 99 ++ LHC + +R RP ++V L + ++ ++ + VE Sbjct: 906 QLMLHCWQKERNHRPKFTDIVSFLDKLIRNPSALHTLVE 944
>EPA4B_XENLA (Q91694) Ephrin type-A receptor 4-B precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor PAG) (Pagliaccio) Length = 985 Score = 37.7 bits (86), Expect = 0.023 Identities = 41/166 (24%), Positives = 73/166 (43%), Gaps = 7/166 (4%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTHATTR----PMGTSGYLDPEYYATSHLSEKSDVY 399 IL+ ++L ++SDFG++R + TTR P+ + PE A + SDV+ Sbjct: 751 ILVNSNLVCKVSDFGMSRVLEDDPEAAYTTRGGKIPI---RWTAPEAIAYRKFTSASDVW 807 Query: 398 SFGILLLVLIT--AQPVIVTANNAKRENISLWVRSRLLEGDIESLTDLRIRGHYDVNSVW 225 S+GI++ +++ +P +N + I R + D I H Sbjct: 808 SYGIVMWEVMSYGERPYWDMSNQDVIKAIEEGYR-------LPPPMDCPIALH------- 853 Query: 224 KVAEMALHCTEHKRQDRPTMMEVVEGLKEGLQLENS-SRSSVETGR 90 ++ L C + R DRP ++V L + ++ NS R+ +E R Sbjct: 854 ---QLMLDCWQKDRSDRPKFGQIVSMLDKLIRNPNSLKRTGLENSR 896
>EPHA2_HUMAN (P29317) Ephrin type-A receptor 2 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor ECK) (Epithelial cell kinase) Length = 976 Score = 37.7 bits (86), Expect = 0.023 Identities = 34/156 (21%), Positives = 72/156 (46%), Gaps = 3/156 (1%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSE-MSTHATTRPMGTSGYLDPEYYATSHLSEKSDVYSFG 390 IL+ ++L ++SDFGL+R + +T+ T+ + PE + + SDV+SFG Sbjct: 745 ILVNSNLVCKVSDFGLSRVLEDDPEATYTTSGGKIPIRWTAPEAISYRKFTSASDVWSFG 804 Query: 389 ILLLVLIT--AQPVIVTANNAKRENISLWVRSRLLEGDIESLTDLRIRGHYDVNSVWKVA 216 I++ ++T +P +N+ + I+ R+ D S + Sbjct: 805 IVMWEVMTYGERPYWELSNHEVMKAIN---------------DGFRLPTPMDCPSA--IY 847 Query: 215 EMALHCTEHKRQDRPTMMEVVEGLKEGLQLENSSRS 108 ++ + C + +R RP ++V L + ++ +S ++ Sbjct: 848 QLMMQCWQQERARRPKFADIVSILDKLIRAPDSLKT 883
>KPCA_RAT (P05696) Protein kinase C alpha type (EC 2.7.11.13) (PKC-alpha)| (PKC-A) Length = 671 Score = 37.7 bits (86), Expect = 0.023 Identities = 21/71 (29%), Positives = 37/71 (52%), Gaps = 1/71 (1%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTHATTRPM-GTSGYLDPEYYATSHLSEKSDVYSFG 390 ++L ++ +I+DFG+ + M TTR GT Y+ PE A + D +++G Sbjct: 468 VMLDSEGHIKIADFGMCK---EHMMDGVTTRTFCGTPDYIAPEIIAYQPYGKSVDWWAYG 524 Query: 389 ILLLVLITAQP 357 +LL ++ QP Sbjct: 525 VLLYEMLAGQP 535
>KPCA_RABIT (P10102) Protein kinase C alpha type (EC 2.7.11.13) (PKC-alpha)| (PKC-A) Length = 671 Score = 37.7 bits (86), Expect = 0.023 Identities = 21/71 (29%), Positives = 37/71 (52%), Gaps = 1/71 (1%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTHATTRPM-GTSGYLDPEYYATSHLSEKSDVYSFG 390 ++L ++ +I+DFG+ + M TTR GT Y+ PE A + D +++G Sbjct: 468 VMLDSEGHIKIADFGMCK---EHMMDGVTTRTFCGTPDYIAPEIIAYQPYGKSVDWWAYG 524 Query: 389 ILLLVLITAQP 357 +LL ++ QP Sbjct: 525 VLLYEMLAGQP 535
>KPCA_HUMAN (P17252) Protein kinase C alpha type (EC 2.7.11.13) (PKC-alpha)| (PKC-A) Length = 671 Score = 37.7 bits (86), Expect = 0.023 Identities = 21/71 (29%), Positives = 37/71 (52%), Gaps = 1/71 (1%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTHATTRPM-GTSGYLDPEYYATSHLSEKSDVYSFG 390 ++L ++ +I+DFG+ + M TTR GT Y+ PE A + D +++G Sbjct: 468 VMLDSEGHIKIADFGMCK---EHMMDGVTTRTFCGTPDYIAPEIIAYQPYGKSVDWWAYG 524 Query: 389 ILLLVLITAQP 357 +LL ++ QP Sbjct: 525 VLLYEMLAGQP 535
>KPCA_BOVIN (P04409) Protein kinase C alpha type (EC 2.7.11.13) (PKC-alpha)| (PKC-A) Length = 671 Score = 37.7 bits (86), Expect = 0.023 Identities = 21/71 (29%), Positives = 37/71 (52%), Gaps = 1/71 (1%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTHATTRPM-GTSGYLDPEYYATSHLSEKSDVYSFG 390 ++L ++ +I+DFG+ + M TTR GT Y+ PE A + D +++G Sbjct: 468 VMLDSEGHIKIADFGMCK---EHMMDGVTTRTFCGTPDYIAPEIIAYQPYGKSVDWWAYG 524 Query: 389 ILLLVLITAQP 357 +LL ++ QP Sbjct: 525 VLLYEMLAGQP 535
>INSR_DROME (P09208) Insulin-like receptor precursor (EC 2.7.10.1) (DIR) (DInr)| (dIRH) [Contains: Insulin-like receptor alpha subunit; Insulin-like receptor beta 1 subunit; Insulin-like receptor beta 2 subunit] Length = 2144 Score = 37.7 bits (86), Expect = 0.023 Identities = 31/143 (21%), Positives = 60/143 (41%), Gaps = 2/143 (1%) Frame = -2 Query: 563 LLTADLEARISDFGLTRAFSSEMSTHATTRPMGTSGYLDPEYYATSHLSEKSDVYSFGIL 384 ++ DL +I DFG+TR T+ + ++ PE S SDV+SFG++ Sbjct: 1526 MVADDLTVKIGDFGMTRDIYETDYYRKGTKGLLPVRWMPPESLRDGVYSSASDVFSFGVV 1585 Query: 383 L--LVLITAQPVIVTANNAKRENISLWVRSRLLEGDIESLTDLRIRGHYDVNSVWKVAEM 210 L + + AQP +N V +++G + + N + ++ Sbjct: 1586 LWEMATLAAQPYQGLSNEQ--------VLRYVIDGGVMERPE---------NCPDFLHKL 1628 Query: 209 ALHCTEHKRQDRPTMMEVVEGLK 141 C H+ RP+ ++++ L+ Sbjct: 1629 MQRCWHHRSSARPSFLDIIAYLE 1651
>EPHA4_MOUSE (Q03137) Ephrin type-A receptor 4 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor SEK) (MPK-3) Length = 986 Score = 37.7 bits (86), Expect = 0.023 Identities = 41/166 (24%), Positives = 74/166 (44%), Gaps = 7/166 (4%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTHATTR----PMGTSGYLDPEYYATSHLSEKSDVY 399 IL+ ++L ++SDFG++R + TTR P+ + PE A + SDV+ Sbjct: 752 ILVNSNLVCKVSDFGMSRVLEDDPEAAYTTRGGKIPI---RWTAPEAIAYRKFTSASDVW 808 Query: 398 SFGILLLVLIT--AQPVIVTANNAKRENISLWVRSRLLEGDIESLTDLRIRGHYDVNSVW 225 S+GI++ +++ +P +N + I R + D I H Sbjct: 809 SYGIVMWEVMSYGERPYWDMSNQDVIKAIEEGYR-------LPPPMDCPIALH------- 854 Query: 224 KVAEMALHCTEHKRQDRPTMMEVVEGLKEGLQLENS-SRSSVETGR 90 ++ L C + +R DRP ++V L + ++ NS R+ E+ R Sbjct: 855 ---QLMLDCWQKERSDRPKFGQIVNMLDKLIRNPNSLKRTGSESSR 897
>EPHA4_CHICK (Q07496) Ephrin type-A receptor 4 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor CEK8) Length = 986 Score = 37.7 bits (86), Expect = 0.023 Identities = 41/166 (24%), Positives = 74/166 (44%), Gaps = 7/166 (4%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTHATTR----PMGTSGYLDPEYYATSHLSEKSDVY 399 IL+ ++L ++SDFG++R + TTR P+ + PE A + SDV+ Sbjct: 752 ILVNSNLVCKVSDFGMSRVLEDDPEAAYTTRGGKIPI---RWTAPEAIAYRKFTSASDVW 808 Query: 398 SFGILLLVLIT--AQPVIVTANNAKRENISLWVRSRLLEGDIESLTDLRIRGHYDVNSVW 225 S+GI++ +++ +P +N + I R + D I H Sbjct: 809 SYGIVMWEVMSYGERPYWDMSNQDVIKAIEEGYR-------LPPPMDCPIALH------- 854 Query: 224 KVAEMALHCTEHKRQDRPTMMEVVEGLKEGLQLENS-SRSSVETGR 90 ++ L C + +R DRP ++V L + ++ NS R+ E+ R Sbjct: 855 ---QLMLDCWQKERSDRPKFGQIVNMLDKLIRNPNSLKRTGSESSR 897
>KPC1_CAEEL (P34722) Protein kinase C-like 1 (EC 2.7.11.13) (PKC)| (Tetradecanoyl phorbol acetate resistant protein 1) Length = 704 Score = 37.7 bits (86), Expect = 0.023 Identities = 20/69 (28%), Positives = 36/69 (52%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTHATTRPMGTSGYLDPEYYATSHLSEKSDVYSFGI 387 +LL D +++DFG+ + + + A+T GT Y+ PE +E D +SFG+ Sbjct: 505 VLLDCDGHIKLADFGMAKTEMNRENGMASTF-CGTPDYISPEIIKGQLYNEAVDFWSFGV 563 Query: 386 LLLVLITAQ 360 L+ ++ Q Sbjct: 564 LMYEMLVGQ 572
>E2AK1_RAT (Q63185) Eukaryotic translation initiation factor 2-alpha kinase 1| (EC 2.7.11.1) (Heme-regulated eukaryotic initiation factor eIF-2-alpha kinase) (Heme-regulated inhibitor) (Heme-controlled repressor) (HCR) (Hemin-sensitive initiation factor 2- Length = 620 Score = 37.7 bits (86), Expect = 0.023 Identities = 25/70 (35%), Positives = 32/70 (45%), Gaps = 10/70 (14%) Frame = -2 Query: 551 DLEARISDFGLTRAFSSEMSTHATTRP----------MGTSGYLDPEYYATSHLSEKSDV 402 D + +I DFGL A + S T R +GT Y PE S KSD+ Sbjct: 452 DQQVKIGDFGLACADIIQKSADWTNRNGKGTPTHTSRVGTCLYASPEQLEGSEYDAKSDM 511 Query: 401 YSFGILLLVL 372 YS G++LL L Sbjct: 512 YSLGVILLEL 521
>YES_XIPHE (P27447) Tyrosine-protein kinase Yes (EC 2.7.10.2) (p61-Yes)| Length = 543 Score = 37.4 bits (85), Expect = 0.030 Identities = 40/145 (27%), Positives = 56/145 (38%), Gaps = 2/145 (1%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTHATTRPMGTSGYLDPEYYATSHLSEKSDVYSFGI 387 IL+ +L +I+DFGL R T A + PE + KSDV+SFGI Sbjct: 402 ILVADNLVCKIADFGLARLIEDNEYT-ARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGI 460 Query: 386 LLLVLIT--AQPVIVTANNAKRENISLWVRSRLLEGDIESLTDLRIRGHYDVNSVWKVAE 213 LL L+T P N E + R +G ESL E Sbjct: 461 LLTELVTKGRVPYPGMVNREVLEQVDRGYRMPCPQGCPESL-----------------HE 503 Query: 212 MALHCTEHKRQDRPTMMEVVEGLKE 138 M C + + +RPT + L++ Sbjct: 504 MMRQCWKKEPDERPTFEYIQSFLED 528
>NEK8_MOUSE (Q91ZR4) Serine/threonine-protein kinase Nek8 (EC 2.7.11.1) (Never| in mitosis A-related kinase 8) (NimA-related protein kinase 8) Length = 698 Score = 37.4 bits (85), Expect = 0.030 Identities = 19/67 (28%), Positives = 35/67 (52%) Frame = -2 Query: 539 RISDFGLTRAFSSEMSTHATTRPMGTSGYLDPEYYATSHLSEKSDVYSFGILLLVLITAQ 360 +I DFG+++ SS+ + +GT Y+ PE ++KSD+++ G +L L + + Sbjct: 144 KIGDFGISKILSSKSKAYTV---VGTPCYISPELCEGKPYNQKSDIWALGCVLYELASLK 200 Query: 359 PVIVTAN 339 AN Sbjct: 201 RAFEAAN 207
>ABL_MLVAB (P00521) Tyrosine-protein kinase transforming protein Abl (EC| 2.7.10.2) (V-abl) Length = 746 Score = 37.4 bits (85), Expect = 0.030 Identities = 43/149 (28%), Positives = 64/149 (42%), Gaps = 2/149 (1%) Frame = -2 Query: 539 RISDFGLTRAFSSEMST-HATTR-PMGTSGYLDPEYYATSHLSEKSDVYSFGILLLVLIT 366 +++DFGL+R + + T HA + P+ + PE A + S KSDV++FG+LL Sbjct: 264 KVADFGLSRLMTGDTYTAHAGAKFPIKWTA---PESLAYNKFSIKSDVWAFGVLLW---- 316 Query: 365 AQPVIVTANNAKRENISLWVRSRLLEGDIESLTDLRIRGHYDVNSVWKVAEMALHCTEHK 186 I T + I L LLE D R KV E+ C + Sbjct: 317 ---EIATYGMSPYPGIDLSQVYELLEKD--------YRMERPEGCPEKVYELMRACWQWN 365 Query: 185 RQDRPTMMEVVEGLKEGLQLENSSRSSVE 99 DRP+ E+ + + Q E+S VE Sbjct: 366 PSDRPSFAEIHQAFETMFQ-ESSISDEVE 393
>ILPR_BRALA (O02466) Insulin-like peptide receptor precursor (EC 2.7.10.1) (ILP| receptor) [Contains: Insulin-like peptide receptor alpha chain; Insulin-like peptide receptor beta chain] Length = 1363 Score = 37.4 bits (85), Expect = 0.030 Identities = 34/147 (23%), Positives = 63/147 (42%), Gaps = 2/147 (1%) Frame = -2 Query: 563 LLTADLEARISDFGLTRAFSSEMSTHATTRPMGTSGYLDPEYYATSHLSEKSDVYSFGIL 384 ++ D +I DFG+TR + + ++ PE + +SDV+S+G++ Sbjct: 1155 MVAQDRTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMSPESLKVGVFTSQSDVWSYGVV 1214 Query: 383 L--LVLITAQPVIVTANNAKRENISLWVRSRLLEGDIESLTDLRIRGHYDVNSVWKVAEM 210 L + + +QP +N E + + +LE L YD+ + Sbjct: 1215 LWEMATLASQPYQGKSNE---EVLKFVIDGGMLEKPEGCPNKL-----YDLMKL------ 1260 Query: 209 ALHCTEHKRQDRPTMMEVVEGLKEGLQ 129 C ++++ RPT +E+VE L LQ Sbjct: 1261 ---CWQYRQSMRPTFLEIVEILSPELQ 1284
>MLTK_MOUSE (Q9ESL4) Mitogen-activated protein kinase kinase kinase MLT (EC| 2.7.11.25) (MLK-like mitogen-activated protein triple kinase) (Leucine zipper-and sterile alpha motif kinase ZAK) (Sterile alpha motif- and leucine zipper-containing kinase AZK) ( Length = 802 Score = 37.4 bits (85), Expect = 0.030 Identities = 21/69 (30%), Positives = 40/69 (57%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTHATTRPMGTSGYLDPEYYATSHLSEKSDVYSFGI 387 +++ AD +I DFG +R + +TH + +GT ++ PE + +SE D YS+G+ Sbjct: 139 VVIAADGVLKICDFGASRFHNH--TTHMSL--VGTFPWMAPEVIQSLPVSETCDTYSYGV 194 Query: 386 LLLVLITAQ 360 +L ++T + Sbjct: 195 VLWEMLTRE 203
>EPHB1_RAT (P09759) Ephrin type-B receptor 1 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EPH-2) (ELK) Length = 984 Score = 37.4 bits (85), Expect = 0.030 Identities = 21/65 (32%), Positives = 35/65 (53%), Gaps = 3/65 (4%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTHATTRPMGTS---GYLDPEYYATSHLSEKSDVYS 396 IL+ ++L ++SDFGL+R + S T +G + PE A + SDV+S Sbjct: 750 ILVNSNLVCKVSDFGLSRYLQDDTSDPTYTSSLGGKIPVRWTAPEAIAYRKFTSASDVWS 809 Query: 395 FGILL 381 +GI++ Sbjct: 810 YGIVM 814
>EPHB1_HUMAN (P54762) Ephrin type-B receptor 1 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EPH-2) (NET) (HEK6) (ELK) Length = 984 Score = 37.4 bits (85), Expect = 0.030 Identities = 21/65 (32%), Positives = 35/65 (53%), Gaps = 3/65 (4%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTHATTRPMGTS---GYLDPEYYATSHLSEKSDVYS 396 IL+ ++L ++SDFGL+R + S T +G + PE A + SDV+S Sbjct: 750 ILVNSNLVCKVSDFGLSRYLQDDTSDPTYTSSLGGKIPVRWTAPEAIAYRKFTSASDVWS 809 Query: 395 FGILL 381 +GI++ Sbjct: 810 YGIVM 814
>EPHB1_CHICK (Q07494) Ephrin type-B receptor 1 (EC 2.7.10.1) (Tyrosine-protein| kinase receptor EPH-2) (Tyrosine kinase CEK6 receptor) (Fragment) Length = 984 Score = 37.4 bits (85), Expect = 0.030 Identities = 21/65 (32%), Positives = 35/65 (53%), Gaps = 3/65 (4%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTHATTRPMGTS---GYLDPEYYATSHLSEKSDVYS 396 IL+ ++L ++SDFGL+R + S T +G + PE A + SDV+S Sbjct: 750 ILVNSNLVCKVSDFGLSRYLQDDTSDPTYTSSLGGKIPVRWTAPEAIAYRKFTSASDVWS 809 Query: 395 FGILL 381 +GI++ Sbjct: 810 YGIVM 814
>ST17A_HUMAN (Q9UEE5) Serine/threonine-protein kinase 17A (EC 2.7.11.1) (DAP| kinase-related apoptosis-inducing protein kinase 1) Length = 414 Score = 37.4 bits (85), Expect = 0.030 Identities = 23/70 (32%), Positives = 38/70 (54%), Gaps = 3/70 (4%) Frame = -2 Query: 566 ILLTADL---EARISDFGLTRAFSSEMSTHATTRPMGTSGYLDPEYYATSHLSEKSDVYS 396 ILLT++ + +I DFGL+R + MGT Y+ PE + +S +D++S Sbjct: 192 ILLTSESPLGDIKIVDFGLSRILKNSEELREI---MGTPEYVAPEILSYDPISMATDMWS 248 Query: 395 FGILLLVLIT 366 G+L V++T Sbjct: 249 IGVLTYVMLT 258
>NEK9_HUMAN (Q8TD19) Serine/threonine-protein kinase Nek9 (EC 2.7.11.1)| (NimA-related protein kinase 9) (Never in mitosis A-related kinase 9) (Nercc1 kinase) (NIMA-related kinase 8) (Nek8) Length = 979 Score = 37.4 bits (85), Expect = 0.030 Identities = 31/139 (22%), Positives = 62/139 (44%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTHATTRPMGTSGYLDPEYYATSHLSEKSDVYSFGI 387 I LT ++ D+GL + +SE S T +GT Y+ PE + KSD+++ G Sbjct: 182 IFLTKANLIKLGDYGLAKKLNSEYSMAETL--VGTPYYMSPELCQGVKYNFKSDIWAVGC 239 Query: 386 LLLVLITAQPVIVTANNAKRENISLWVRSRLLEGDIESLTDLRIRGHYDVNSVWKVAEMA 207 ++ L+T + N N+ + + + +++S Y + ++ +M Sbjct: 240 VIFELLTLKRTFDATNPL---NLCVKIVQGIRAMEVDS-------SQYSL----ELIQMV 285 Query: 206 LHCTEHKRQDRPTMMEVVE 150 C + + RPT E+++ Sbjct: 286 HSCLDQDPEQRPTADELLD 304
>PSK1_SCHPO (Q12706) Serine/threonine-protein kinase psk1 (EC 2.7.11.22)| Length = 436 Score = 37.4 bits (85), Expect = 0.030 Identities = 26/79 (32%), Positives = 37/79 (46%) Frame = -2 Query: 563 LLTADLEARISDFGLTRAFSSEMSTHATTRPMGTSGYLDPEYYATSHLSEKSDVYSFGIL 384 LL A+ ++DFGL++ + + +GT Y PE D +S GIL Sbjct: 222 LLDAEGHILLTDFGLSKVAENGADCRSF---VGTEEYCAPEILLEQPYDHAVDWWSMGIL 278 Query: 383 LLVLITAQPVIVTANNAKR 327 + L+T P TANN KR Sbjct: 279 IFDLLTGSPPF-TANNHKR 296
>IGF1R_XENLA (O73798) Insulin-like growth factor 1 receptor precursor (EC| 2.7.10.1) (xIGF-1R) (xIGFR) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain] Length = 1358 Score = 37.4 bits (85), Expect = 0.030 Identities = 32/146 (21%), Positives = 60/146 (41%), Gaps = 2/146 (1%) Frame = -2 Query: 563 LLTADLEARISDFGLTRAFSSEMSTHATTRPMGTSGYLDPEYYATSHLSEKSDVYSFGIL 384 ++T D +I DFG+TR + + ++ PE + SDV+SFG++ Sbjct: 1138 MVTEDFTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMSPESLKDGVFTTNSDVWSFGVV 1197 Query: 383 L--LVLITAQPVIVTANNAKRENISLWVRSRLLEGDIESLTDLRIRGHYDVNSVWKVAEM 210 L + + QP +N V ++EG + D N + E+ Sbjct: 1198 LWEIATLAEQPYQGMSNEQ--------VLRFVMEGGLLEKPD---------NCPDMLFEL 1240 Query: 209 ALHCTEHKRQDRPTMMEVVEGLKEGL 132 C + + RP+ +E++ +K+ L Sbjct: 1241 MRMCWQFNPKMRPSFLEIISSIKDEL 1266
>EPHA6_HUMAN (Q9UF33) Ephrin type-A receptor 6 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EHK-2) (EPH homology kinase 2) Length = 1035 Score = 37.4 bits (85), Expect = 0.030 Identities = 37/159 (23%), Positives = 69/159 (43%), Gaps = 3/159 (1%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSE-MSTHATTRPMGTSGYLDPEYYATSHLSEKSDVYSFG 390 IL+ ++L ++SDFGL+R + + + TT + PE A S SD +S+G Sbjct: 803 ILVNSNLVCKVSDFGLSRVLEDDPEAAYTTTGGKIPIRWTAPEAIAYRKFSSASDAWSYG 862 Query: 389 ILLLVLIT--AQPVIVTANNAKRENISLWVRSRLLEGDIESLTDLRIRGHYDVNSVWKVA 216 I++ +++ +P +N +I R G SL Sbjct: 863 IVMWEVMSYGERPYWEMSNQDVILSIEEGYRLPAPMGCPASL-----------------H 905 Query: 215 EMALHCTEHKRQDRPTMMEVVEGLKEGLQLENSSRSSVE 99 ++ LHC + +R RP ++V L + ++ ++ + VE Sbjct: 906 QLMLHCWQKERNHRPKFTDIVSFLDKLIRNPSALHTLVE 944
>ABL1_HUMAN (P00519) Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2)| (p150) (c-ABL) (Abelson murine leukemia viral oncogene homolog 1) Length = 1130 Score = 37.4 bits (85), Expect = 0.030 Identities = 43/149 (28%), Positives = 64/149 (42%), Gaps = 2/149 (1%) Frame = -2 Query: 539 RISDFGLTRAFSSEMST-HATTR-PMGTSGYLDPEYYATSHLSEKSDVYSFGILLLVLIT 366 +++DFGL+R + + T HA + P+ + PE A + S KSDV++FG+LL Sbjct: 378 KVADFGLSRLMTGDTYTAHAGAKFPIKWTA---PESLAYNKFSIKSDVWAFGVLLW---- 430 Query: 365 AQPVIVTANNAKRENISLWVRSRLLEGDIESLTDLRIRGHYDVNSVWKVAEMALHCTEHK 186 I T + I L LLE D R KV E+ C + Sbjct: 431 ---EIATYGMSPYPGIDLSQVYELLEKD--------YRMERPEGCPEKVYELMRACWQWN 479 Query: 185 RQDRPTMMEVVEGLKEGLQLENSSRSSVE 99 DRP+ E+ + + Q E+S VE Sbjct: 480 PSDRPSFAEIHQAFETMFQ-ESSISDEVE 507
>CHK1_DROME (O61661) Serine/threonine-protein kinase grp (EC 2.7.11.1) (Protein| grapes) (Chk1 homolog) Length = 512 Score = 37.4 bits (85), Expect = 0.030 Identities = 17/69 (24%), Positives = 36/69 (52%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTHATTRPMGTSGYLDPEYYATSHLSEKSDVYSFGI 387 +LL +ISDFG+ F + + GT Y+ PE ++ ++ +D++S G+ Sbjct: 149 LLLDEHDNVKISDFGMATMFRCKGKERLLDKRCGTLPYVAPEVLQKAYHAQPADLWSCGV 208 Query: 386 LLLVLITAQ 360 +L+ ++ + Sbjct: 209 ILVTMLAGE 217
>MLTK_HUMAN (Q9NYL2) Mitogen-activated protein kinase kinase kinase MLT (EC| 2.7.11.25) (MLK-like mitogen-activated protein triple kinase) (Leucine zipper-and sterile alpha motif-containing kinase) (Sterile alpha motif- and leucine zipper-containing kinase Length = 800 Score = 37.4 bits (85), Expect = 0.030 Identities = 21/69 (30%), Positives = 40/69 (57%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTHATTRPMGTSGYLDPEYYATSHLSEKSDVYSFGI 387 +++ AD +I DFG +R + +TH + +GT ++ PE + +SE D YS+G+ Sbjct: 139 VVIAADGVLKICDFGASRFHNH--TTHMSL--VGTFPWMAPEVIQSLPVSETCDTYSYGV 194 Query: 386 LLLVLITAQ 360 +L ++T + Sbjct: 195 VLWEMLTRE 203
>FRK_HUMAN (P42685) Tyrosine-protein kinase FRK (EC 2.7.10.2) (Nuclear| tyrosine protein kinase RAK) Length = 505 Score = 37.4 bits (85), Expect = 0.030 Identities = 24/63 (38%), Positives = 34/63 (53%), Gaps = 5/63 (7%) Frame = -2 Query: 539 RISDFGLTRAFSSEM-----STHATTRPMGTSGYLDPEYYATSHLSEKSDVYSFGILLLV 375 +++DFGL R F + S H P+ + PE ++ S KSDV+SFGILL Sbjct: 369 KVADFGLARVFKVDNEDIYESRHEIKLPVKWTA---PEAIRSNKFSIKSDVWSFGILLYE 425 Query: 374 LIT 366 +IT Sbjct: 426 IIT 428
>ABL1_MOUSE (P00520) Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2)| (p150) (c-ABL) (Abelson murine leukemia viral oncogene homolog 1) Length = 1123 Score = 37.4 bits (85), Expect = 0.030 Identities = 43/149 (28%), Positives = 64/149 (42%), Gaps = 2/149 (1%) Frame = -2 Query: 539 RISDFGLTRAFSSEMST-HATTR-PMGTSGYLDPEYYATSHLSEKSDVYSFGILLLVLIT 366 +++DFGL+R + + T HA + P+ + PE A + S KSDV++FG+LL Sbjct: 378 KVADFGLSRLMTGDTYTAHAGAKFPIKWTA---PESLAYNKFSIKSDVWAFGVLLW---- 430 Query: 365 AQPVIVTANNAKRENISLWVRSRLLEGDIESLTDLRIRGHYDVNSVWKVAEMALHCTEHK 186 I T + I L LLE D R KV E+ C + Sbjct: 431 ---EIATYGMSPYPGIDLSQVYELLEKD--------YRMERPEGCPEKVYELMRACWQWN 479 Query: 185 RQDRPTMMEVVEGLKEGLQLENSSRSSVE 99 DRP+ E+ + + Q E+S VE Sbjct: 480 PSDRPSFAEIHQAFETMFQ-ESSISDEVE 507
>STE7_YEAST (P06784) Serine/threonine-protein kinase STE7 (EC 2.7.12.2)| Length = 515 Score = 37.4 bits (85), Expect = 0.030 Identities = 18/69 (26%), Positives = 40/69 (57%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTHATTRPMGTSGYLDPEYYATSHLSEKSDVYSFGI 387 +L+ + + ++ DFG+++ + ++ +GTS Y+ PE + S K DV+S G+ Sbjct: 337 VLINSKGQIKLCDFGVSKKLINSIADTF----VGTSTYMSPERIQGNVYSIKGDVWSLGL 392 Query: 386 LLLVLITAQ 360 +++ L+T + Sbjct: 393 MIIELVTGE 401
>NEK8_HUMAN (Q86SG6) Serine/threonine-protein kinase Nek8 (EC 2.7.11.1) (Never| in mitosis A-related kinase 8) (NimA-related protein kinase 8) (NIMA-related kinase 12a) Length = 692 Score = 37.4 bits (85), Expect = 0.030 Identities = 19/67 (28%), Positives = 35/67 (52%) Frame = -2 Query: 539 RISDFGLTRAFSSEMSTHATTRPMGTSGYLDPEYYATSHLSEKSDVYSFGILLLVLITAQ 360 +I DFG+++ SS+ + +GT Y+ PE ++KSD+++ G +L L + + Sbjct: 144 KIGDFGISKILSSKSKAYTV---VGTPCYISPELCEGKPYNQKSDIWALGCVLYELASLK 200 Query: 359 PVIVTAN 339 AN Sbjct: 201 RAFEAAN 207
>EPHA3_BRARE (O13146) Ephrin type-A receptor 3 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor ZEK1) (EPH-like kinase 1) Length = 981 Score = 37.4 bits (85), Expect = 0.030 Identities = 36/147 (24%), Positives = 61/147 (41%), Gaps = 6/147 (4%) Frame = -2 Query: 566 ILLTADLEARISDFGLTRAFSSEMSTHATTR----PMGTSGYLDPEYYATSHLSEKSDVY 399 IL+ +L ++SDFGL+R + TTR P+ + PE + SDV+ Sbjct: 757 ILVNRNLVCKVSDFGLSRVLEDDPEAAYTTRGGKIPI---RWTAPEAITYRKFTSASDVW 813 Query: 398 SFGILLLVLIT--AQPVIVTANNAKRENISLWVRSRLLEGDIESLTDLRIRGHYDVNSVW 225 S+GI++ +I+ +P +N D+ D R ++ Sbjct: 814 SYGIVMWEVISYGERPYWEMSNQ-----------------DVIKAVDEGYRLPAPMDCPV 856 Query: 224 KVAEMALHCTEHKRQDRPTMMEVVEGL 144 + ++ L C E R DRP ++V L Sbjct: 857 VLHQLMLDCWEKNRSDRPKFGQIVNTL 883 Database: uniprot_sprot.fasta Posted date: May 25, 2006 5:36 PM Number of letters in database: 80,573,946 Number of sequences in database: 219,361 Lambda K H 0.318 0.135 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 82,721,869 Number of Sequences: 219361 Number of extensions: 1700039 Number of successful extensions: 6044 Number of sequences better than 10.0: 500 Number of HSP's better than 10.0 without gapping: 5495 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 5852 length of database: 80,573,946 effective HSP length: 106 effective length of database: 57,321,680 effective search space used: 4700377760 frameshift window, decay const: 50, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
