ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
menu 
| Clone Name | rbasd20n21 |
|---|---|
| Clone Library Name | barley_pub |
>SRK6_BRAOE (Q09092) Putative serine/threonine-protein kinase receptor precursor| (EC 2.7.11.1) (S-receptor kinase) (SRK) Length = 849 Score = 137 bits (346), Expect = 2e-32 Identities = 68/138 (49%), Positives = 92/138 (66%), Gaps = 6/138 (4%) Frame = -3 Query: 621 KSSGHTGYMSPEYAMDGVFSMKSDIYSFGVMVLEIVTGKKNRGFYDAELDLNLLGYAWTL 442 K G GYMSPEYAM G+FS KSD++SFGV+VLEIV+GKKNRGFY+ + + +LL Y W+ Sbjct: 689 KVVGTYGYMSPEYAMYGIFSEKSDVFSFGVIVLEIVSGKKNRGFYNLDYENDLLSYVWSR 748 Query: 441 WKEGRSTELLDEAMMGSSCDH------SQVRRCIQVALLCVDMNPRNRPLMSSIVMMLAT 280 WKEGR+ E++D ++ S +V +CIQ+ LLCV +RP MSS+V M + Sbjct: 749 WKEGRALEIVDPVIVDSLSSQPSIFQPQEVLKCIQIGLLCVQELAEHRPAMSSVVWMFGS 808 Query: 279 ENATLPEPNEPGGNVGKS 226 E +P+P PG V +S Sbjct: 809 EATEIPQPKPPGYCVRRS 826
>RLCK7_ARATH (Q9LQQ8) Probable serine/threonine-protein kinase RLCKVII (EC| 2.7.11.1) Length = 423 Score = 86.3 bits (212), Expect = 7e-17 Identities = 44/131 (33%), Positives = 76/131 (58%) Frame = -3 Query: 612 GHTGYMSPEYAMDGVFSMKSDIYSFGVMVLEIVTGKKNRGFYDAELDLNLLGYAWTLWKE 433 G GY +P+YAM G + KSDIYSFGV++LE++TG+K D NL+G+A L+K+ Sbjct: 269 GTYGYCAPDYAMTGQLTFKSDIYSFGVVLLELITGRKAIDNTKTRKDQNLVGWARPLFKD 328 Query: 432 GRSTELLDEAMMGSSCDHSQVRRCIQVALLCVDMNPRNRPLMSSIVMMLATENATLPEPN 253 R+ + + ++ + + + ++ +CV P RP++S +V+ L ++ +PN Sbjct: 329 RRNFPKMVDPLLQGQYPVRGLYQALAISAMCVQEQPTMRPVVSDVVLALNFLASSKYDPN 388 Query: 252 EPGGNVGKSTS 220 P + GK+ S Sbjct: 389 SPSSSSGKNPS 399
>BAK1_ARATH (Q94F62) BRASSINOSTEROID INSENSITIVE 1-associated receptor kinase 1| precursor (EC 2.7.11.1) (BRI1-associated receptor kinase 1) (Somatic embryogenesis receptor-like kinase 3) Length = 615 Score = 74.7 bits (182), Expect = 2e-13 Identities = 46/113 (40%), Positives = 67/113 (59%), Gaps = 4/113 (3%) Frame = -3 Query: 612 GHTGYMSPEYAMDGVFSMKSDIYSFGVMVLEIVTGKKNRGFYDAEL----DLNLLGYAWT 445 G G+++PEY G S K+D++ +GVM+LE++TG+ R F A L D+ LL + Sbjct: 454 GTIGHIAPEYLSTGKSSEKTDVFGYGVMLLELITGQ--RAFDLARLANDDDVMLLDWVKG 511 Query: 444 LWKEGRSTELLDEAMMGSSCDHSQVRRCIQVALLCVDMNPRNRPLMSSIVMML 286 L KE + L+D + G+ D +V + IQVALLC +P RP MS +V ML Sbjct: 512 LLKEKKLEALVDVDLQGNYKD-EEVEQLIQVALLCTQSSPMERPKMSEVVRML 563
>EXS_ARATH (Q9LYN8) Leucine-rich repeat receptor protein kinase EXS precursor| (EC 2.7.11.1) (Extra sporogenous cells protein) (EXCESS MICROSPOROCYTES1 protein) Length = 1192 Score = 72.8 bits (177), Expect = 8e-13 Identities = 40/112 (35%), Positives = 69/112 (61%), Gaps = 2/112 (1%) Frame = -3 Query: 615 SGHTGYMSPEYAMDGVFSMKSDIYSFGVMVLEIVTGKKNRG--FYDAELDLNLLGYAWTL 442 +G GY+ PEY + K D+YSFGV++LE+VTGK+ G F ++E NL+G+A Sbjct: 1080 AGTFGYIPPEYGQSARATTKGDVYSFGVILLELVTGKEPTGPDFKESE-GGNLVGWAIQK 1138 Query: 441 WKEGRSTELLDEAMMGSSCDHSQVRRCIQVALLCVDMNPRNRPLMSSIVMML 286 +G++ +++D ++ + +SQ+ R +Q+A+LC+ P RP M ++ L Sbjct: 1139 INQGKAVDVIDPLLVSVALKNSQL-RLLQIAMLCLAETPAKRPNMLDVLKAL 1189
>BRL3_ARATH (Q9LJF3) Serine/threonine-protein kinase BRI1-like 3 precursor (EC| 2.7.11.1) (BRASSINOSTEROID INSENSITIVE 1-like protein 3) Length = 1164 Score = 72.4 bits (176), Expect = 1e-12 Identities = 41/125 (32%), Positives = 69/125 (55%), Gaps = 6/125 (4%) Frame = -3 Query: 615 SGHTGYMSPEYAMDGVFSMKSDIYSFGVMVLEIVTGKKNRGFYDAELDLNLLGYAWTLWK 436 +G GY+ PEY + K D+YS+GV++LE+++GKK + D NL+G+A L++ Sbjct: 1023 AGTPGYVPPEYYQSFRCTAKGDVYSYGVILLELLSGKKPIDPEEFGEDNNLVGWAKQLYR 1082 Query: 435 EGRSTELLDEAMMGSSCDHSQVRRCIQVALLCVDMNPRNRPLMSSIVMM------LATEN 274 E R E+LD ++ ++ +++A C+D P RP M ++ M + TEN Sbjct: 1083 EKRGAEILDPELVTDKSGDVELLHYLKIASQCLDDRPFKRPTMIQVMTMFKELVQVDTEN 1142 Query: 273 ATLPE 259 +L E Sbjct: 1143 DSLDE 1147
>BRL1_ARATH (Q9ZWC8) Serine/threonine-protein kinase BRI1-like 1 precursor (EC| 2.7.11.1) (BRASSINOSTEROID INSENSITIVE 1-like protein 1) Length = 1166 Score = 70.1 bits (170), Expect = 5e-12 Identities = 38/119 (31%), Positives = 64/119 (53%) Frame = -3 Query: 615 SGHTGYMSPEYAMDGVFSMKSDIYSFGVMVLEIVTGKKNRGFYDAELDLNLLGYAWTLWK 436 +G GY+ PEY + K D+YS+GV++LE+++GKK + D NL+G+A L++ Sbjct: 1025 AGTPGYVPPEYYQSFRCTAKGDVYSYGVILLELLSGKKPIDPGEFGEDNNLVGWAKQLYR 1084 Query: 435 EGRSTELLDEAMMGSSCDHSQVRRCIQVALLCVDMNPRNRPLMSSIVMMLATENATLPE 259 E R E+LD ++ ++ +++A C+D P RP M ++ M A E Sbjct: 1085 EKRGAEILDPELVTDKSGDVELFHYLKIASQCLDDRPFKRPTMIQLMAMFKEMKADTEE 1143
>PBS1_ARATH (Q9FE20) Serine/threonine-protein kinase PBS1 (EC 2.7.11.1)| (AvrPphB susceptible protein 1) Length = 456 Score = 67.4 bits (163), Expect = 3e-11 Identities = 38/113 (33%), Positives = 64/113 (56%), Gaps = 3/113 (2%) Frame = -3 Query: 612 GHTGYMSPEYAMDGVFSMKSDIYSFGVMVLEIVTGKKNRGFYDAEL---DLNLLGYAWTL 442 G GY +PEYAM G ++KSD+YSFGV+ LE++TG+K D+E+ + NL+ +A L Sbjct: 252 GTYGYCAPEYAMTGQLTVKSDVYSFGVVFLELITGRK---AIDSEMPHGEQNLVAWARPL 308 Query: 441 WKEGRSTELLDEAMMGSSCDHSQVRRCIQVALLCVDMNPRNRPLMSSIVMMLA 283 + + R L + + + + + VA +C+ RPL++ +V L+ Sbjct: 309 FNDRRKFIKLADPRLKGRFPTRALYQALAVASMCIQEQAATRPLIADVVTALS 361
>PSKR_ARATH (Q9ZVR7) Putative phytosulfokine receptor precursor (EC 2.7.11.1)| (Phytosulfokine LRR receptor kinase) Length = 1008 Score = 65.5 bits (158), Expect = 1e-10 Identities = 34/109 (31%), Positives = 59/109 (54%) Frame = -3 Query: 612 GHTGYMSPEYAMDGVFSMKSDIYSFGVMVLEIVTGKKNRGFYDAELDLNLLGYAWTLWKE 433 G GY+ PEY V + K D+YSFGV++LE++T K+ + +L+ + + E Sbjct: 898 GTLGYIPPEYGQASVATYKGDVYSFGVVLLELLTDKRPVDMCKPKGCRDLISWVVKMKHE 957 Query: 432 GRSTELLDEAMMGSSCDHSQVRRCIQVALLCVDMNPRNRPLMSSIVMML 286 R++E+ D + D ++ R +++A LC+ NP+ RP +V L Sbjct: 958 SRASEVFDPLIYSKEND-KEMFRVLEIACLCLSENPKQRPTTQQLVSWL 1005
>RLK5_ARATH (P47735) Receptor-like protein kinase 5 precursor (EC 2.7.11.1)| Length = 999 Score = 63.5 bits (153), Expect = 5e-10 Identities = 47/145 (32%), Positives = 75/145 (51%), Gaps = 3/145 (2%) Frame = -3 Query: 615 SGHTGYMSPEYAMDGVFSMKSDIYSFGVMVLEIVTGKKNRGFYDAEL-DLNLLGYAWTLW 439 +G GY++PEY + KSDIYSFGV++LE+VTGK+ D+EL D ++ + T Sbjct: 859 AGSCGYIAPEYVYTLRVNEKSDIYSFGVVLLELVTGKQPT---DSELGDKDMAKWVCTAL 915 Query: 438 KEGRSTELLDEAMMGSSCDHSQVRRCIQVALLCVDMNPRNRPLMSSIVMMLATENATLP- 262 + ++D + ++ + I + LLC P NRP M +V+ML + +P Sbjct: 916 DKCGLEPVIDPKL--DLKFKEEISKVIHIGLLCTSPLPLNRPSMRKVVIMLQEVSGAVPC 973 Query: 261 -EPNEPGGNVGKSTSDGELSQTQSE 190 PN +S + G+LS +E Sbjct: 974 SSPN----TSKRSKTGGKLSPYYTE 994
>RPK1_IPONI (P93194) Receptor-like protein kinase precursor (EC 2.7.11.1)| Length = 1109 Score = 63.2 bits (152), Expect = 6e-10 Identities = 38/114 (33%), Positives = 64/114 (56%), Gaps = 5/114 (4%) Frame = -3 Query: 612 GHTGYMSPEYAMDGVFSMKSDIYSFGVMVLEIVTGKKNRG-FYDAELDLNLLGYAWTLWK 436 G GYM+PE A V S +SD+YS+GV++LE++T KK ++ E D ++G+ ++W Sbjct: 981 GTIGYMAPENAFTTVKSRESDVYSYGVVLLELITRKKALDPSFNGETD--IVGWVRSVWT 1038 Query: 435 E-GRSTELLDEAMMGSSCDHS---QVRRCIQVALLCVDMNPRNRPLMSSIVMML 286 + G +++D +++ D S QV + +AL C + RP M +V L Sbjct: 1039 QTGEIQKIVDPSLLDELIDSSVMEQVTEALSLALRCAEKEVDKRPTMRDVVKQL 1092
>BRL2_ARATH (Q9ZPS9) Serine/threonine-protein kinase BRI1-like 2 precursor (EC| 2.7.11.1) (BRASSINOSTEROID INSENSITIVE 1-like protein 2) (Protein VASCULAR HIGHWAY 1) Length = 1143 Score = 62.8 bits (151), Expect = 8e-10 Identities = 39/124 (31%), Positives = 64/124 (51%), Gaps = 14/124 (11%) Frame = -3 Query: 615 SGHTGYMSPEYAMDGVFSMKSDIYSFGVMVLEIVTGKKNRGFYDAELDLNLLGYAWTLWK 436 +G GY+ PEY + K D+YS GV++LEI++GK+ + D NL+G++ + Sbjct: 1004 AGTPGYVPPEYYQSFRCTAKGDVYSIGVVMLEILSGKRPTDKEEFG-DTNLVGWSKMKAR 1062 Query: 435 EGRSTELLDEAMMGSSCDHS--------------QVRRCIQVALLCVDMNPRNRPLMSSI 298 EG+ E++DE ++ S ++ R +++AL CVD P RP M + Sbjct: 1063 EGKHMEVIDEDLLKEGSSESLNEKEGFEGGVIVKEMLRYLEIALRCVDDFPSKRPNMLQV 1122 Query: 297 VMML 286 V L Sbjct: 1123 VASL 1126
>PSKR_DAUCA (Q8LPB4) Phytosulfokine receptor precursor (EC 2.7.11.1)| (Phytosulfokine LRR receptor kinase) Length = 1021 Score = 61.6 bits (148), Expect = 2e-09 Identities = 33/110 (30%), Positives = 58/110 (52%), Gaps = 1/110 (0%) Frame = -3 Query: 612 GHTGYMSPEYAMDGVFSMKSDIYSFGVMVLEIVTGKKNRGFYDAELDLNLLGYAWTLWKE 433 G GY+ PEY V + K D+YSFGV++LE++TG++ +L+ + + E Sbjct: 907 GTLGYIPPEYGQASVATYKGDVYSFGVVLLELLTGRRPMDVCKPRGSRDLISWVLQMKTE 966 Query: 432 GRSTELLDEAMMGSSCDHS-QVRRCIQVALLCVDMNPRNRPLMSSIVMML 286 R +E+ D + DH+ ++ +++A C+ NP+ RP +V L Sbjct: 967 KRESEIFDPFIYDK--DHAEEMLLVLEIACRCLGENPKTRPTTQQLVSWL 1014
>NORK_MEDTR (Q8L4H4) Nodulation receptor kinase precursor (EC 2.7.11.1) (Does not| make infections protein 2) (Symbiosis receptor-like kinase) (MtSYMRK) Length = 925 Score = 61.6 bits (148), Expect = 2e-09 Identities = 40/121 (33%), Positives = 67/121 (55%), Gaps = 1/121 (0%) Frame = -3 Query: 612 GHTGYMSPEYAMDGVFSMKSDIYSFGVMVLEIVTGKKNRGFYDAELDLNLLGYAWTLWKE 433 G GY+ PEY S KSD++SFGV++LEIV+G++ ++ +L+ +A + Sbjct: 761 GTAGYLDPEYYKTQQLSEKSDVFSFGVVLLEIVSGREPLNIKRPRIEWSLVEWAKPYIRA 820 Query: 432 GRSTELLDEAMMGSSCDHSQ-VRRCIQVALLCVDMNPRNRPLMSSIVMMLATENATLPEP 256 + E++D + G H++ + R ++VAL C++ RP M IV L E+A + E Sbjct: 821 SKVDEIVDPGIKGGY--HAEALWRVVEVALQCLEPYSTYRPCMVDIVREL--EDALIIEN 876 Query: 255 N 253 N Sbjct: 877 N 877
>CLV1_ARATH (Q9SYQ8) Receptor protein kinase CLAVATA1 precursor (EC 2.7.11.1)| Length = 980 Score = 61.2 bits (147), Expect = 2e-09 Identities = 38/117 (32%), Positives = 60/117 (51%), Gaps = 7/117 (5%) Frame = -3 Query: 615 SGHTGYMSPEYAMDGVFSMKSDIYSFGVMVLEIVTGKKNRGFYDAELDLNLLGYAWTLWK 436 +G GY++PEYA KSD+YSFGV++LE++ GKK G + +D+ W Sbjct: 855 AGSYGYIAPEYAYTLKVDEKSDVYSFGVVLLELIAGKKPVGEFGEGVDI----VRWVRNT 910 Query: 435 EGRSTELLDEAMMGSSCDH-------SQVRRCIQVALLCVDMNPRNRPLMSSIVMML 286 E T+ D A++ + D + V ++A++CV+ RP M +V ML Sbjct: 911 EEEITQPSDAAIVVAIVDPRLTGYPLTSVIHVFKIAMMCVEEEAAARPTMREVVHML 967
>NORK_PEA (Q8LKZ1) Nodulation receptor kinase precursor (EC 2.7.11.1)| Length = 924 Score = 61.2 bits (147), Expect = 2e-09 Identities = 40/121 (33%), Positives = 67/121 (55%), Gaps = 1/121 (0%) Frame = -3 Query: 612 GHTGYMSPEYAMDGVFSMKSDIYSFGVMVLEIVTGKKNRGFYDAELDLNLLGYAWTLWKE 433 G GY+ PEY S KSD++SFGV++LEIV+G++ ++ +L+ +A + Sbjct: 760 GTAGYLDPEYYKTQQLSEKSDVFSFGVVLLEIVSGREPLNIKRPRVEWSLVEWAKPYIRA 819 Query: 432 GRSTELLDEAMMGSSCDHSQ-VRRCIQVALLCVDMNPRNRPLMSSIVMMLATENATLPEP 256 + E++D + G H++ + R ++VAL C++ RP M IV L E+A + E Sbjct: 820 SKVDEIVDPGIKGGY--HAEALWRVVEVALQCLEPYSTYRPCMVDIVREL--EDALIIEN 875 Query: 255 N 253 N Sbjct: 876 N 876
>CRI4_MAIZE (O24585) Putative receptor protein kinase CRINKLY4 precursor (EC| 2.7.11.1) Length = 901 Score = 58.9 bits (141), Expect = 1e-08 Identities = 38/110 (34%), Positives = 58/110 (52%) Frame = -3 Query: 615 SGHTGYMSPEYAMDGVFSMKSDIYSFGVMVLEIVTGKKNRGFYDAELDLNLLGYAWTLWK 436 +G GY+ PEY + KSD+YSFGV++LEI++G+K E N++ +A L K Sbjct: 672 AGTLGYLDPEYYRLHYLTTKSDVYSFGVVLLEILSGRKAIDMQFEE--GNIVEWAVPLIK 729 Query: 435 EGRSTELLDEAMMGSSCDHSQVRRCIQVALLCVDMNPRNRPLMSSIVMML 286 G +LD + S D +++ VA CV M ++RP M + L Sbjct: 730 AGDIFAILDPVLSPPS-DLEALKKIASVACKCVRMRGKDRPSMDKVTTAL 778
>NAK_ARATH (P43293) Probable serine/threonine-protein kinase NAK (EC 2.7.11.1)| Length = 389 Score = 58.2 bits (139), Expect = 2e-08 Identities = 35/110 (31%), Positives = 63/110 (57%), Gaps = 4/110 (3%) Frame = -3 Query: 612 GHTGYMSPEYAMDGVFSMKSDIYSFGVMVLEIVTGKKNRGFYDAELDLNLLGYAWT-LWK 436 G GY +PEY G S+KSD+YSFGV++LE+++G++ + NL+ +A L Sbjct: 242 GTQGYAAPEYLATGHLSVKSDVYSFGVVLLELLSGRRAIDKNQPVGEHNLVDWARPYLTN 301 Query: 435 EGRSTELLDEAMMGSSCDHSQVRRCIQVALL---CVDMNPRNRPLMSSIV 295 + R ++D + G + R +++A+L C+ ++ ++RP M+ IV Sbjct: 302 KRRLLRVMDPRLQG----QYSLTRALKIAVLALDCISIDAKSRPTMNEIV 347
>BRI1_LYCPE (Q8L899) Systemin receptor SR160 precursor (EC 2.7.11.1)| (Brassinosteroid LRR receptor kinase) Length = 1207 Score = 57.0 bits (136), Expect = 4e-08 Identities = 35/110 (31%), Positives = 60/110 (54%), Gaps = 1/110 (0%) Frame = -3 Query: 615 SGHTGYMSPEYAMDGVFSMKSDIYSFGVMVLEIVTGKKNRGFYDAELDLNLLGYAWTLWK 436 +G GY+ PEY S K D+YS+GV++LE++TGK+ D D NL+G+ L Sbjct: 1052 AGTPGYVPPEYYQSFRCSTKGDVYSYGVVLLELLTGKQPTDSADFG-DNNLVGWV-KLHA 1109 Query: 435 EGRSTELLDEAMMGSSCD-HSQVRRCIQVALLCVDMNPRNRPLMSSIVMM 289 +G+ T++ D ++ ++ + ++VA C+D RP M ++ M Sbjct: 1110 KGKITDVFDRELLKEDASIEIELLQHLKVACACLDDRHWKRPTMIQVMAM 1159
>BRI1_LYCES (Q8GUQ5) Brassinosteroid LRR receptor kinase precursor (EC 2.7.11.1)| (tBRI1) (Altered brassinolide sensitivity 1) (Systemin receptor SR160) Length = 1207 Score = 57.0 bits (136), Expect = 4e-08 Identities = 35/110 (31%), Positives = 60/110 (54%), Gaps = 1/110 (0%) Frame = -3 Query: 615 SGHTGYMSPEYAMDGVFSMKSDIYSFGVMVLEIVTGKKNRGFYDAELDLNLLGYAWTLWK 436 +G GY+ PEY S K D+YS+GV++LE++TGK+ D D NL+G+ L Sbjct: 1052 AGTPGYVPPEYYQSFRCSTKGDVYSYGVVLLELLTGKQPTDSADFG-DNNLVGWV-KLHA 1109 Query: 435 EGRSTELLDEAMMGSSCD-HSQVRRCIQVALLCVDMNPRNRPLMSSIVMM 289 +G+ T++ D ++ ++ + ++VA C+D RP M ++ M Sbjct: 1110 KGKITDVFDRELLKEDASIEIELLQHLKVACACLDDRHWKRPTMIQVMAM 1159
>TMK1_ARATH (P43298) Putative receptor protein kinase TMK1 precursor (EC| 2.7.11.1) Length = 942 Score = 56.6 bits (135), Expect = 6e-08 Identities = 33/114 (28%), Positives = 61/114 (53%), Gaps = 2/114 (1%) Frame = -3 Query: 615 SGHTGYMSPEYAMDGVFSMKSDIYSFGVMVLEIVTGKKNRGFYDAELDLNLLGYAWTLW- 439 +G GY++PEYA+ G + K D+YSFGV+++E++TG+K+ E ++L+ + ++ Sbjct: 754 AGTFGYLAPEYAVTGRVTTKVDVYSFGVILMELITGRKSLDESQPEESIHLVSWFKRMYI 813 Query: 438 -KEGRSTELLDEAMMGSSCDHSQVRRCIQVALLCVDMNPRNRPLMSSIVMMLAT 280 KE + +D + + V ++A C P RP M V +L++ Sbjct: 814 NKEASFKKAIDTTIDLDEETLASVHTVAELAGHCCAREPYQRPDMGHAVNILSS 867
>CX32_ARATH (P27450) Probable serine/threonine-protein kinase Cx32, chloroplast| precursor (EC 2.7.11.1) Length = 419 Score = 53.5 bits (127), Expect = 5e-07 Identities = 36/118 (30%), Positives = 62/118 (52%), Gaps = 9/118 (7%) Frame = -3 Query: 612 GHTGYMSPEYAMDGVFSMKSDIYSFGVMVLEIVTG------KKNRGFYDAELDLNLLGYA 451 G GY +PEY G +KSD+++FGV++LEI+TG K+ RG ++ +D Sbjct: 257 GTYGYAAPEYMATGHLYVKSDVFAFGVVLLEIMTGLTAHNTKRPRG-QESLVD------- 308 Query: 450 W---TLWKEGRSTELLDEAMMGSSCDHSQVRRCIQVALLCVDMNPRNRPLMSSIVMML 286 W L + R +++D+ + G ++ L C++ +P+NRP M +V +L Sbjct: 309 WLRPELSNKHRVKQIMDKGIKGQYTT-KVATEMARITLSCIEPDPKNRPHMKEVVEVL 365
>KPEL_DROME (Q05652) Probable serine/threonine-protein kinase pelle (EC| 2.7.11.1) Length = 501 Score = 53.1 bits (126), Expect = 6e-07 Identities = 34/106 (32%), Positives = 57/106 (53%), Gaps = 4/106 (3%) Frame = -3 Query: 600 YMSPEYAMDGVFSMKSDIYSFGVMVLEIVTGKK-NRGFYDAELDLNLLGYAWTLWKEGRS 424 Y+ PE+ S D+YSFG+++LE+ TG++ + E NLL Y W++ R Sbjct: 390 YLPPEFRNFRQLSTGVDVYSFGIVLLEVFTGRQVTDRVPENETKKNLLDYVKQQWRQNR- 448 Query: 423 TELLDE---AMMGSSCDHSQVRRCIQVALLCVDMNPRNRPLMSSIV 295 ELL++ A MG D I+ L C ++P++RP M++++ Sbjct: 449 MELLEKHLAAPMGKELDMCMC--AIEAGLHCTALDPQDRPSMNAVL 492
>SIRK_ARATH (O64483) Senescence-induced receptor-like serine/threonine-protein| kinase precursor (FLG22-induced receptor-like kinase 1) Length = 876 Score = 53.1 bits (126), Expect = 6e-07 Identities = 31/110 (28%), Positives = 55/110 (50%) Frame = -3 Query: 615 SGHTGYMSPEYAMDGVFSMKSDIYSFGVMVLEIVTGKKNRGFYDAELDLNLLGYAWTLWK 436 +G GY+ PEY + KSD+YS GV++LE++TG+ E +++ + ++ Sbjct: 735 AGSIGYLDPEYYSTRQMNEKSDVYSLGVVLLEVITGQPAIASSKTE-KVHISDHVRSILA 793 Query: 435 EGRSTELLDEAMMGSSCDHSQVRRCIQVALLCVDMNPRNRPLMSSIVMML 286 G ++D+ + D + ++AL C + RP MS +VM L Sbjct: 794 NGDIRGIVDQRLR-ERYDVGSAWKMSEIALACTEHTSAQRPTMSQVVMEL 842
>BRI1_ARATH (O22476) BRASSINOSTEROID INSENSITIVE 1 precursor (EC 2.7.11.1)| (AtBRI1) (Brassinosteroid LRR receptor kinase) Length = 1196 Score = 52.8 bits (125), Expect = 8e-07 Identities = 35/109 (32%), Positives = 55/109 (50%) Frame = -3 Query: 615 SGHTGYMSPEYAMDGVFSMKSDIYSFGVMVLEIVTGKKNRGFYDAELDLNLLGYAWTLWK 436 +G GY+ PEY S K D+YS+GV++LE++TGK+ D D NL+G+ K Sbjct: 1047 AGTPGYVPPEYYQSFRCSTKGDVYSYGVVLLELLTGKRPTDSPDFG-DNNLVGWVKQHAK 1105 Query: 435 EGRSTELLDEAMMGSSCDHSQVRRCIQVALLCVDMNPRNRPLMSSIVMM 289 S E M ++ + ++VA+ C+D RP M ++ M Sbjct: 1106 LRISDVFDPELMKEDPALEIELLQHLKVAVACLDDRAWRRPTMVQVMAM 1154
>APK1A_ARATH (Q06548) Protein kinase APK1A, chloroplast precursor (EC 2.7.11.1)| Length = 410 Score = 49.3 bits (116), Expect = 9e-06 Identities = 36/132 (27%), Positives = 63/132 (47%), Gaps = 3/132 (2%) Frame = -3 Query: 612 GHTGYMSPEYAMDGVFSMKSDIYSFGVMVLEIVTGKKNRGFYDAELDLNLLGYAWTLWKE 433 G GY +PEY G + KSD+YSFGV++LE+++G++ + NL+ +A Sbjct: 242 GTHGYAAPEYLATGHLTTKSDVYSFGVVLLELLSGRRAVDKNRPSGERNLVEWAKPYLVN 301 Query: 432 GRSTELLDEAMMGSSCDHSQVRRCIQVALLCVDMNPRNRPLMSSIVMML---ATENATLP 262 R + + + + + ++L C+ + RP MS +V L + NA + Sbjct: 302 KRKIFRVIDNRLQDQYSMEEACKVATLSLRCLTTEIKLRPNMSEVVSHLEHIQSLNAAI- 360 Query: 261 EPNEPGGNVGKS 226 GGN+ K+ Sbjct: 361 -----GGNMDKT 367
>APK1B_ARATH (P46573) Protein kinase APK1B, chloroplast precursor (EC 2.7.11.1)| Length = 412 Score = 48.1 bits (113), Expect = 2e-05 Identities = 33/124 (26%), Positives = 58/124 (46%) Frame = -3 Query: 612 GHTGYMSPEYAMDGVFSMKSDIYSFGVMVLEIVTGKKNRGFYDAELDLNLLGYAWTLWKE 433 G GY +PEY G + KSD+YS+GV++LE+++G++ + L+ +A L Sbjct: 243 GTYGYAAPEYLATGHLTTKSDVYSYGVVLLEVLSGRRAVDKNRPPGEQKLVEWARPLLAN 302 Query: 432 GRSTELLDEAMMGSSCDHSQVRRCIQVALLCVDMNPRNRPLMSSIVMMLATENATLPEPN 253 R + + + + + +AL C+ + RP M+ +V L + N Sbjct: 303 KRKLFRVIDNRLQDQYSMEEACKVATLALRCLTFEIKLRPNMNEVVSHL----EHIQTLN 358 Query: 252 EPGG 241 E GG Sbjct: 359 EAGG 362
>IRAK4_MOUSE (Q8R4K2) Interleukin-1 receptor-associated kinase 4 (EC 2.7.11.1)| (IRAK-4) Length = 459 Score = 47.0 bits (110), Expect = 5e-05 Identities = 40/120 (33%), Positives = 58/120 (48%), Gaps = 6/120 (5%) Frame = -3 Query: 612 GHTGYMSPEYAMDGVFSMKSDIYSFGVMVLEIVTGKKNRGFYDAELDLN-----LLGYAW 448 G T YM+PE A+ G + KSDIYSFGV++LE++TG A +D N LL Sbjct: 350 GTTAYMAPE-ALRGEITPKSDIYSFGVVLLELITGL-------AAVDENREPQLLLDIKE 401 Query: 447 TLWKEGRSTE-LLDEAMMGSSCDHSQVRRCIQVALLCVDMNPRNRPLMSSIVMMLATENA 271 + E ++ E DE M S D + V A C+ RP ++ + +L +A Sbjct: 402 EIEDEEKTIEDYTDEKM--SDADPASVEAMYSAASQCLHEKKNRRPDIAKVQQLLQEMSA 459
>KPRO_MAIZE (P17801) Putative receptor protein kinase ZmPK1 precursor (EC| 2.7.11.1) Length = 817 Score = 46.6 bits (109), Expect = 6e-05 Identities = 31/116 (26%), Positives = 56/116 (48%), Gaps = 7/116 (6%) Frame = -3 Query: 612 GHTGYMSPEYAMDGVFSMKSDIYSFGVMVLEIVTGKKNR----GFYDAELDLNLLGYAWT 445 G GY++PE+ + K D+YS+GV++LE++TG + G + L L + Sbjct: 697 GTLGYIAPEWVSSLPITAKVDVYSYGVVLLELLTGTRVSELVGGTDEVHSMLRKLVRMLS 756 Query: 444 LWKEGRSTELLD---EAMMGSSCDHSQVRRCIQVALLCVDMNPRNRPLMSSIVMML 286 EG +D ++ + ++ Q R I++A+ C++ + RP M V L Sbjct: 757 AKLEGEEQSWIDGYLDSKLNRPVNYVQARTLIKLAVSCLEEDRSKRPTMEHAVQTL 812
>IRAK3_HUMAN (Q9Y616) Interleukin-1 receptor-associated kinase 3 (EC 2.7.11.1)| (IRAK-3) (IL-1 receptor-associated kinase M) (IRAK-M) Length = 596 Score = 45.8 bits (107), Expect = 1e-04 Identities = 18/37 (48%), Positives = 27/37 (72%) Frame = -3 Query: 618 SSGHTGYMSPEYAMDGVFSMKSDIYSFGVMVLEIVTG 508 SS H YM EY G S+K+D+YSFG++++E++TG Sbjct: 334 SSKHLWYMPEEYIRQGKLSIKTDVYSFGIVIMEVLTG 370
>IRAK4_HUMAN (Q9NWZ3) Interleukin-1 receptor-associated kinase 4 (EC 2.7.11.1)| (IRAK-4) (NY-REN-64 antigen) Length = 460 Score = 45.4 bits (106), Expect = 1e-04 Identities = 37/116 (31%), Positives = 56/116 (48%), Gaps = 1/116 (0%) Frame = -3 Query: 612 GHTGYMSPEYAMDGVFSMKSDIYSFGVMVLEIVTGKKNRGFYDAELDLNLLGYAWTLWKE 433 G T YM+PE A+ G + KSDIYSFGV++LEI+TG + LL + E Sbjct: 350 GTTAYMAPE-ALRGEITPKSDIYSFGVVLLEIITGLP--AVDEHREPQLLLDIKEEIEDE 406 Query: 432 GRSTE-LLDEAMMGSSCDHSQVRRCIQVALLCVDMNPRNRPLMSSIVMMLATENAT 268 ++ E +D+ M + D + V VA C+ RP + + +L A+ Sbjct: 407 EKTIEDYIDKKM--NDADSTSVEAMYSVASQCLHEKKNKRPDIKKVQQLLQEMTAS 460
>ROS_HUMAN (P08922) Proto-oncogene tyrosine-protein kinase ROS precursor (EC| 2.7.10.1) (c-ros-1) Length = 2347 Score = 44.7 bits (104), Expect = 2e-04 Identities = 21/52 (40%), Positives = 35/52 (67%) Frame = -3 Query: 600 YMSPEYAMDGVFSMKSDIYSFGVMVLEIVTGKKNRGFYDAELDLNLLGYAWT 445 +M+PE MDG+F+ +SD++SFG+++ EI+T Y A +L++L Y T Sbjct: 2127 WMAPESLMDGIFTTQSDVWSFGILIWEILT--LGHQPYPAHSNLDVLNYVQT 2176
>IRAK3_MOUSE (Q8K4B2) Interleukin-1 receptor-associated kinase 3 (EC 2.7.11.1)| (IRAK-3) (IL-1 receptor-associated kinase M) (IRAK-M) Length = 609 Score = 44.3 bits (103), Expect = 3e-04 Identities = 33/122 (27%), Positives = 53/122 (43%), Gaps = 1/122 (0%) Frame = -3 Query: 609 HTGYMSPEYAMDGVFSMKSDIYSFGVMVLEIVTGKKNRGFYDAELDLNLLGYAWTLW-KE 433 H YM EY G S+K+D+YSFG++++E++TG K D + L L K Sbjct: 350 HLWYMPEEYIRQGRLSVKTDVYSFGIVIMEVLTGCK--VVLDDPKHVQLRDLLMELMEKR 407 Query: 432 GRSTELLDEAMMGSSCDHSQVRRCIQVALLCVDMNPRNRPLMSSIVMMLATENATLPEPN 253 G + L C + + +A CV + RP M ++ L + +L Sbjct: 408 GLDSCLSFLDRKIPPCPRNFSAKLFSLAGRCVATKAKLRPTMDEVLSSLESTQPSLYFAE 467 Query: 252 EP 247 +P Sbjct: 468 DP 469
>M3LK7_DROME (P83104) Putative mitogen-activated protein kinase kinase kinase| 7-like (EC 2.7.11.25) Length = 393 Score = 42.7 bits (99), Expect = 9e-04 Identities = 35/114 (30%), Positives = 51/114 (44%), Gaps = 2/114 (1%) Frame = -3 Query: 612 GHTGYMSPEYAMDGVFSMKSDIYSFGVMVLEIVTGKKNRGFYDAELDLNLLGYAWTLWKE 433 G YM+PE ++ K D+YSFG+M+ E++T R + L+ YA + K Sbjct: 168 GTLRYMAPEAIKHLKYTAKCDVYSFGIMLWELMT----RQLPYSHLENPNSQYA--IMKA 221 Query: 432 GRSTELLDEAMMGSSCDH--SQVRRCIQVALLCVDMNPRNRPLMSSIVMMLATE 277 S E L + S C Q+ C C+D+NP RP M I L + Sbjct: 222 ISSGEKLPMEAVRSDCPEGIKQLMEC------CMDINPEKRPSMKEIEKFLGEQ 269
>INSR_XENLA (Q9PVZ4) Insulin receptor precursor (EC 2.7.10.1) (IR) (Xe-InsR)| (XTK-1b) [Contains: Insulin receptor alpha subunit; Insulin receptor beta subunit] Length = 1362 Score = 42.7 bits (99), Expect = 9e-04 Identities = 32/107 (29%), Positives = 49/107 (45%), Gaps = 2/107 (1%) Frame = -3 Query: 600 YMSPEYAMDGVFSMKSDIYSFGVMVLEIVTGKKNRGFYDAELDLNLLGYAWTLWKEGRST 421 +MSPE DGVF+ SD++SFGV++ EI + A ++ + Sbjct: 1191 WMSPESLKDGVFTAFSDVWSFGVVLWEITS------------------LAEQPYQGLSNE 1232 Query: 420 ELLDEAMMGSSCDHSQ--VRRCIQVALLCVDMNPRNRPLMSSIVMML 286 ++L M G S DH + R + +C NP+ RP I+ ML Sbjct: 1233 QVLKFVMDGGSLDHPENCPPRLHSLMQMCWQYNPKMRPTFLEIIDML 1279
>STE7_YEAST (P06784) Serine/threonine-protein kinase STE7 (EC 2.7.12.2)| Length = 515 Score = 42.7 bits (99), Expect = 9e-04 Identities = 17/36 (47%), Positives = 27/36 (75%) Frame = -3 Query: 612 GHTGYMSPEYAMDGVFSMKSDIYSFGVMVLEIVTGK 505 G + YMSPE V+S+K D++S G+M++E+VTG+ Sbjct: 366 GTSTYMSPERIQGNVYSIKGDVWSLGLMIIELVTGE 401
>HTK7_HYDAT (Q25197) Putative insulin-like peptide receptor precursor (EC| 2.7.10.1) Length = 1477 Score = 41.2 bits (95), Expect = 0.003 Identities = 35/115 (30%), Positives = 49/115 (42%), Gaps = 7/115 (6%) Frame = -3 Query: 600 YMSPEYAMDGVFSMKSDIYSFGVMVLEIVT-------GKKNRGFYDAELDLNLLGYAWTL 442 +M+PE DG+FS SD++SFGV++ EI T GK N + L L Y Sbjct: 1218 WMAPESLKDGIFSTASDVWSFGVVLWEICTLASQPYQGKTNEQVLNFVLSNGHLDYP--- 1274 Query: 441 WKEGRSTELLDEAMMGSSCDHSQVRRCIQVALLCVDMNPRNRPLMSSIVMMLATE 277 CD+ Q+R + LC +P+ RP IV +L E Sbjct: 1275 ----------------EGCDY-QLREFMS---LCWHRDPKMRPSFLEIVHVLENE 1309
>PKN2_BACSU (O34507) Probable serine/threonine-protein kinase yloP (EC| 2.7.11.1) Length = 648 Score = 40.4 bits (93), Expect = 0.004 Identities = 16/36 (44%), Positives = 26/36 (72%) Frame = -3 Query: 612 GHTGYMSPEYAMDGVFSMKSDIYSFGVMVLEIVTGK 505 G Y+SPE A G+ + KSDIY+ G+++ E++TG+ Sbjct: 172 GSVHYLSPEQARGGLATKKSDIYALGIVLFELLTGR 207
>INSR_MOUSE (P15208) Insulin receptor precursor (EC 2.7.10.1) (IR) [Contains:| Insulin receptor alpha subunit; Insulin receptor beta subunit] Length = 1372 Score = 40.4 bits (93), Expect = 0.004 Identities = 43/172 (25%), Positives = 70/172 (40%), Gaps = 4/172 (2%) Frame = -3 Query: 600 YMSPEYAMDGVFSMKSDIYSFGVMVLEIVTGKKNRGFYDAELDLNLLGYAWTLWKEGRST 421 +MSPE DGVF+ SD++SFGV++ EI + A ++ + Sbjct: 1192 WMSPESLKDGVFTASSDMWSFGVVLWEITS------------------LAEQPYQGLSNE 1233 Query: 420 ELLDEAMMGSSCD--HSQVRRCIQVALLCVDMNPRNRPLMSSIVMMLATE-NATLPEPNE 250 ++L M G D + R + +C NP+ RP IV +L + + + PE + Sbjct: 1234 QVLKFVMDGGYLDPPDNCPERLTDLMRMCWQFNPKMRPTFLEIVNLLKDDLHPSFPEVSF 1293 Query: 249 PGGNVGKSTSDGELSQTQSEL-TVTVTDTR*FGWTGXDGAEEGILLCVKHTY 97 K+ EL ++ V + + G E G L +K TY Sbjct: 1294 FYSEENKAPESEELEMEFEDMENVPLDRSSHCQREEAGGREGGSSLSIKRTY 1345
>IGF1R_HUMAN (P08069) Insulin-like growth factor 1 receptor precursor (EC| 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD221 antigen) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 recepto Length = 1367 Score = 40.0 bits (92), Expect = 0.006 Identities = 39/133 (29%), Positives = 58/133 (43%), Gaps = 16/133 (12%) Frame = -3 Query: 600 YMSPEYAMDGVFSMKSDIYSFGVMVLEIVT--GKKNRGFYDAELDLNLLGYAWTLWKEGR 427 +MSPE DGVF+ SD++SFGV++ EI T + +G + ++ L + L K Sbjct: 1178 WMSPESLKDGVFTTYSDVWSFGVVLWEIATLAEQPYQGLSNEQV-LRFVMEGGLLDKPDN 1236 Query: 426 STELLDEAMMGSSCDHSQVRRCIQVALLCVDMNPRNRP----LMSSI----------VMM 289 ++L E M +C NP+ RP ++SSI V Sbjct: 1237 CPDMLFELMR-----------------MCWQYNPKMRPSFLEIISSIKEEMEPGFREVSF 1279 Query: 288 LATENATLPEPNE 250 +E LPEP E Sbjct: 1280 YYSEENKLPEPEE 1292
>IGF1R_XENLA (O73798) Insulin-like growth factor 1 receptor precursor (EC| 2.7.10.1) (xIGF-1R) (xIGFR) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain] Length = 1358 Score = 40.0 bits (92), Expect = 0.006 Identities = 31/110 (28%), Positives = 49/110 (44%), Gaps = 2/110 (1%) Frame = -3 Query: 600 YMSPEYAMDGVFSMKSDIYSFGVMVLEIVT--GKKNRGFYDAELDLNLLGYAWTLWKEGR 427 +MSPE DGVF+ SD++SFGV++ EI T + +G + ++ L + L K Sbjct: 1174 WMSPESLKDGVFTTNSDVWSFGVVLWEIATLAEQPYQGMSNEQV-LRFVMEGGLLEKPDN 1232 Query: 426 STELLDEAMMGSSCDHSQVRRCIQVALLCVDMNPRNRPLMSSIVMMLATE 277 ++L E M +C NP+ RP I+ + E Sbjct: 1233 CPDMLFELMR-----------------MCWQFNPKMRPSFLEIISSIKDE 1265
>INSRR_CAVPO (P14617) Insulin receptor-related protein precursor (EC 2.7.10.1)| (IRR) (IR-related receptor) [Contains: Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain] Length = 1300 Score = 40.0 bits (92), Expect = 0.006 Identities = 31/108 (28%), Positives = 52/108 (48%) Frame = -3 Query: 600 YMSPEYAMDGVFSMKSDIYSFGVMVLEIVTGKKNRGFYDAELDLNLLGYAWTLWKEGRST 421 +M+PE DG+F+ SD++SFGV++ EIVT + Y + +L + +G Sbjct: 1158 WMAPESLKDGIFTTHSDVWSFGVVLWEIVTLAEQP--YQGLSNEQVLKFV----MDGGVL 1211 Query: 420 ELLDEAMMGSSCDHSQVRRCIQVALLCVDMNPRNRPLMSSIVMMLATE 277 E L++ C H + ++ C NPR RP + I+ + E Sbjct: 1212 EELED------CPH----QLQELMSSCWQQNPRLRPTFTQILNSIQKE 1249
>NEK9_MOUSE (Q8K1R7) Serine/threonine-protein kinase Nek9 (EC 2.7.11.1)| (NimA-related protein kinase 9) (Never in mitosis A-related kinase 9) Length = 984 Score = 40.0 bits (92), Expect = 0.006 Identities = 28/103 (27%), Positives = 47/103 (45%), Gaps = 1/103 (0%) Frame = -3 Query: 600 YMSPEYAMDGVFSMKSDIYSFGVMVLEIVTGKKNRGFYDAELDLNLLGYAWTLWKEGRST 421 YMSPE ++ KSDI++ G ++ E++T K+ +DA LNL Sbjct: 217 YMSPELCQGVKYNFKSDIWAVGCVIFELLTLKRT---FDATNPLNL-------------C 260 Query: 420 ELLDEAMMGSSCDHSQVR-RCIQVALLCVDMNPRNRPLMSSIV 295 + + + D SQ IQ+ C+D +P RP +++ Sbjct: 261 VKIVQGIRAMEVDSSQYSLELIQLVHACLDQDPEQRPAADALL 303
>PKNL_MYCTU (O53510) Probable serine/threonine-protein kinase pknL (EC| 2.7.11.1) Length = 399 Score = 39.7 bits (91), Expect = 0.007 Identities = 17/35 (48%), Positives = 23/35 (65%) Frame = -3 Query: 612 GHTGYMSPEYAMDGVFSMKSDIYSFGVMVLEIVTG 508 G Y+SPE DG +SD+YS GV+V E++TG Sbjct: 180 GTAAYLSPEQVRDGNADPRSDVYSVGVLVYELLTG 214
>PKNL_MYCBO (Q7TYY6) Probable serine/threonine-protein kinase pknL (EC| 2.7.11.1) Length = 399 Score = 39.7 bits (91), Expect = 0.007 Identities = 17/35 (48%), Positives = 23/35 (65%) Frame = -3 Query: 612 GHTGYMSPEYAMDGVFSMKSDIYSFGVMVLEIVTG 508 G Y+SPE DG +SD+YS GV+V E++TG Sbjct: 180 GTAAYLSPEQVRDGNADPRSDVYSVGVLVYELLTG 214
>INSR_RAT (P15127) Insulin receptor precursor (EC 2.7.10.1) (IR) [Contains:| Insulin receptor alpha subunit; Insulin receptor beta subunit] Length = 1383 Score = 39.7 bits (91), Expect = 0.007 Identities = 43/172 (25%), Positives = 68/172 (39%), Gaps = 4/172 (2%) Frame = -3 Query: 600 YMSPEYAMDGVFSMKSDIYSFGVMVLEIVTGKKNRGFYDAELDLNLLGYAWTLWKEGRST 421 +MSPE DGVF+ SD++SFGV++ EI + A ++ + Sbjct: 1203 WMSPESLKDGVFTASSDMWSFGVVLWEITS------------------LAEQPYQGLSNE 1244 Query: 420 ELLDEAMMGSSCD--HSQVRRCIQVALLCVDMNPRNRPLMSSIVMMLATE-NATLPEPNE 250 ++L M G D + R + +C NP+ RP IV +L + + + PE + Sbjct: 1245 QVLKFVMDGGYLDPPDNCPERLTDLMRMCWQFNPKMRPTFLEIVNLLKDDLHPSFPEVSF 1304 Query: 249 PGGNVGKSTSDGELSQTQSELTVTVTDTR*FGWTGXDGAEE-GILLCVKHTY 97 K+ EL ++ D G E G L +K TY Sbjct: 1305 FYSEENKAPESEELEMEFEDMENVPLDRSSHCQREEAGCREGGSSLSIKRTY 1356
>NEK9_HUMAN (Q8TD19) Serine/threonine-protein kinase Nek9 (EC 2.7.11.1)| (NimA-related protein kinase 9) (Never in mitosis A-related kinase 9) (Nercc1 kinase) (NIMA-related kinase 8) (Nek8) Length = 979 Score = 39.3 bits (90), Expect = 0.010 Identities = 28/103 (27%), Positives = 46/103 (44%), Gaps = 1/103 (0%) Frame = -3 Query: 600 YMSPEYAMDGVFSMKSDIYSFGVMVLEIVTGKKNRGFYDAELDLNLLGYAWTLWKEGRST 421 YMSPE ++ KSDI++ G ++ E++T K+ +DA LNL Sbjct: 217 YMSPELCQGVKYNFKSDIWAVGCVIFELLTLKRT---FDATNPLNL-------------C 260 Query: 420 ELLDEAMMGSSCDHSQVR-RCIQVALLCVDMNPRNRPLMSSIV 295 + + + D SQ IQ+ C+D +P RP ++ Sbjct: 261 VKIVQGIRAMEVDSSQYSLELIQMVHSCLDQDPEQRPTADELL 303
>INSRR_HUMAN (P14616) Insulin receptor-related protein precursor (EC 2.7.10.1)| (IRR) (IR-related receptor) [Contains: Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain] Length = 1297 Score = 38.9 bits (89), Expect = 0.013 Identities = 16/30 (53%), Positives = 24/30 (80%) Frame = -3 Query: 600 YMSPEYAMDGVFSMKSDIYSFGVMVLEIVT 511 +M+PE DG+F+ SD++SFGV++ EIVT Sbjct: 1158 WMAPESLKDGIFTTHSDVWSFGVVLWEIVT 1187
>CAD96_DROME (Q9VBW3) Tyrosine kinase receptor Cad96Ca precursor (EC 2.7.10.1)| (Cadherin 96Ca) (Tyrosine kinase receptor HD-14) Length = 773 Score = 38.9 bits (89), Expect = 0.013 Identities = 29/107 (27%), Positives = 50/107 (46%), Gaps = 2/107 (1%) Frame = -3 Query: 600 YMSPEYAMDGVFSMKSDIYSFGVMVLEIVTGKKNRGFYDAELDLNLLGYAWTLWKEGRST 421 +M+ E D +FS+KSDI+SFG+++ EIVT LG T + + Sbjct: 653 WMATESLYDNIFSVKSDIWSFGILMWEIVT----------------LGS--TPYPGISAA 694 Query: 420 ELLDEAMMGSSCDHSQ--VRRCIQVALLCVDMNPRNRPLMSSIVMML 286 +++ + G + + R + C +P+ RPL + I+ ML Sbjct: 695 DVMRKVRDGYRLEKPEHCRRELYNIMYYCWSHDPQERPLFAEIIQML 741
>INSRR_MOUSE (Q9WTL4) Insulin receptor-related protein precursor (EC 2.7.10.1)| (IRR) (IR-related receptor) [Contains: Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain] Length = 1300 Score = 38.9 bits (89), Expect = 0.013 Identities = 16/30 (53%), Positives = 24/30 (80%) Frame = -3 Query: 600 YMSPEYAMDGVFSMKSDIYSFGVMVLEIVT 511 +M+PE DG+F+ SD++SFGV++ EIVT Sbjct: 1158 WMAPESLKDGIFTTHSDVWSFGVVLWEIVT 1187
>IGF1R_MOUSE (Q60751) Insulin-like growth factor 1 receptor precursor (EC| 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain] Length = 1373 Score = 38.9 bits (89), Expect = 0.013 Identities = 17/30 (56%), Positives = 23/30 (76%) Frame = -3 Query: 600 YMSPEYAMDGVFSMKSDIYSFGVMVLEIVT 511 +MSPE DGVF+ SD++SFGV++ EI T Sbjct: 1180 WMSPESLKDGVFTTHSDVWSFGVVLWEIAT 1209
>IGF1R_BOVIN (Q05688) Insulin-like growth factor 1 receptor precursor (EC| 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain] (F Length = 640 Score = 38.9 bits (89), Expect = 0.013 Identities = 17/30 (56%), Positives = 23/30 (76%) Frame = -3 Query: 600 YMSPEYAMDGVFSMKSDIYSFGVMVLEIVT 511 +MSPE DGVF+ SD++SFGV++ EI T Sbjct: 451 WMSPESLKDGVFTTHSDVWSFGVVLWEIAT 480
>IGF1R_RAT (P24062) Insulin-like growth factor 1 receptor precursor (EC| 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain] Length = 1370 Score = 38.9 bits (89), Expect = 0.013 Identities = 17/30 (56%), Positives = 23/30 (76%) Frame = -3 Query: 600 YMSPEYAMDGVFSMKSDIYSFGVMVLEIVT 511 +MSPE DGVF+ SD++SFGV++ EI T Sbjct: 1179 WMSPESLKDGVFTTHSDVWSFGVVLWEIAT 1208
>PKN2_CLOAB (Q97IC2) Probable serine/threonine protein kinase CAC1728 (EC| 2.7.11.1) Length = 657 Score = 38.9 bits (89), Expect = 0.013 Identities = 27/102 (26%), Positives = 46/102 (45%) Frame = -3 Query: 621 KSSGHTGYMSPEYAMDGVFSMKSDIYSFGVMVLEIVTGKKNRGFYDAELDLNLLGYAWTL 442 K G Y+SPE A ++DIYSFG+++ E+ TGK YDA+ +++ Sbjct: 168 KVVGSAHYLSPEQAQGIPVDCRTDIYSFGIVLYEMATGKVP---YDADTPVSI------- 217 Query: 441 WKEGRSTELLDEAMMGSSCDHSQVRRCIQVALLCVDMNPRNR 316 + D A+ + + ++ L C++ P NR Sbjct: 218 ----ALKHIQDAAVPPNELNKDIPIALNKMILRCIEKKPENR 255
>YES_CHICK (P09324) Tyrosine-protein kinase Yes (EC 2.7.10.2) (p61-Yes)| Length = 540 Score = 38.5 bits (88), Expect = 0.016 Identities = 34/125 (27%), Positives = 56/125 (44%), Gaps = 3/125 (2%) Frame = -3 Query: 600 YMSPEYAMDGVFSMKSDIYSFGVMVLEIVTGKKNRGFYDAELDLNLLGYAWTLWKEGRST 421 + +PE A+ G F++KSD++SFG+++ E+VT K R Y + + Sbjct: 435 WTAPEAALYGRFTIKSDVWSFGILLTELVT--KGRVPYPGMV----------------NR 476 Query: 420 ELLDEAMMG--SSCDHSQVRRCIQVALLCVDMNPRNRPLMSSIVMMLATENATLPEPN-E 250 E+L++ G C ++ LC +P RP I L + T EP + Sbjct: 477 EVLEQVERGYRMPCPQGCPESLHELMKLCWKKDPDERPTFEYIQSFL-EDYFTATEPQYQ 535 Query: 249 PGGNV 235 PG N+ Sbjct: 536 PGDNL 540
>BYR1_SCHPO (P10506) Protein kinase byr1 (EC 2.7.12.2) (MAPK kinase) (MAPKK)| Length = 340 Score = 38.1 bits (87), Expect = 0.021 Identities = 17/51 (33%), Positives = 31/51 (60%) Frame = -3 Query: 612 GHTGYMSPEYAMDGVFSMKSDIYSFGVMVLEIVTGKKNRGFYDAELDLNLL 460 G + YMSPE G +++KSDI+S G+ ++E+ T + F + + + +L Sbjct: 221 GTSTYMSPERIRGGKYTVKSDIWSLGISIIELATQELPWSFSNIDDSIGIL 271
>7LESS_DROME (P13368) Protein sevenless (EC 2.7.10.1)| Length = 2554 Score = 38.1 bits (87), Expect = 0.021 Identities = 15/30 (50%), Positives = 25/30 (83%) Frame = -3 Query: 600 YMSPEYAMDGVFSMKSDIYSFGVMVLEIVT 511 +MSPE +DG+F+ +SD+++FGV+ EI+T Sbjct: 2393 WMSPESLVDGLFTTQSDVWAFGVLCWEILT 2422
>INSR_HUMAN (P06213) Insulin receptor precursor (EC 2.7.10.1) (IR) (CD220| antigen) [Contains: Insulin receptor alpha subunit; Insulin receptor beta subunit] Length = 1382 Score = 37.7 bits (86), Expect = 0.028 Identities = 31/117 (26%), Positives = 51/117 (43%), Gaps = 3/117 (2%) Frame = -3 Query: 600 YMSPEYAMDGVFSMKSDIYSFGVMVLEIVTGKKNRGFYDAELDLNLLGYAWTLWKEGRST 421 +M+PE DGVF+ SD++SFGV++ EI + A ++ + Sbjct: 1202 WMAPESLKDGVFTTSSDMWSFGVVLWEITS------------------LAEQPYQGLSNE 1243 Query: 420 ELLDEAMMGSSCDHSQ--VRRCIQVALLCVDMNPRNRPLMSSIVMMLATE-NATLPE 259 ++L M G D R + +C NP+ RP IV +L + + + PE Sbjct: 1244 QVLKFVMDGGYLDQPDNCPERVTDLMRMCWQFNPKMRPTFLEIVNLLKDDLHPSFPE 1300
>FYN_XIPHE (P27446) Proto-oncogene tyrosine-protein kinase FYN (EC 2.7.10.2)| (P59-FYN) Length = 536 Score = 37.7 bits (86), Expect = 0.028 Identities = 33/125 (26%), Positives = 55/125 (44%), Gaps = 3/125 (2%) Frame = -3 Query: 600 YMSPEYAMDGVFSMKSDIYSFGVMVLEIVTGKKNRGFYDAELDLNLLGYAWTLWKEGRST 421 + +PE A+ G F++KSD++SFG+++ E+VT K R Y + Sbjct: 431 WTAPEAALYGRFTIKSDVWSFGILLTELVT--KGRVPYPGM----------------NNR 472 Query: 420 ELLDEAMMG--SSCDHSQVRRCIQVALLCVDMNPRNRPLMSSIVMMLATENATLPEPN-E 250 E+L++ G C ++ L C +P RP + L + T EP + Sbjct: 473 EVLEQVERGYRMPCPQDCPASLHELMLQCWKKDPEERPTFEYLQAFL-EDYFTATEPQYQ 531 Query: 249 PGGNV 235 PG N+ Sbjct: 532 PGDNL 536
>M3K12_RAT (Q63796) Mitogen-activated protein kinase kinase kinase 12 (EC| 2.7.11.25) (Mixed lineage kinase) (Leucine-zipper protein kinase) (ZPK) (Dual leucine zipper bearing kinase) (DLK) (MAPK-upstream kinase) (MUK) Length = 888 Score = 37.4 bits (85), Expect = 0.037 Identities = 35/124 (28%), Positives = 57/124 (45%), Gaps = 2/124 (1%) Frame = -3 Query: 615 SGHTGYMSPEYAMDGVFSMKSDIYSFGVMVLEIVTGKKNRGFYDAELDLNLLGYAWTLWK 436 +G +M+PE + S K DI+SFGV++ E++TG E+ + + +W Sbjct: 304 AGTVAWMAPEVIRNEPVSEKVDIWSFGVVLWELLTG---------EIPYKDVDSSAIIWG 354 Query: 435 EGRSTELLDEAMMGSSCDHSQVRRCIQVAL-LCVDMNPRNRPLMSSIVMMLATENA-TLP 262 G ++ L + SSC ++ L C + PRNRP I++ L +A L Sbjct: 355 VGSNSLHLP---VPSSCPDG-----FKILLRQCWNRKPRNRPSFRQILLHLDIASADVLS 406 Query: 261 EPNE 250 P E Sbjct: 407 TPQE 410
>M3K12_MOUSE (Q60700) Mitogen-activated protein kinase kinase kinase 12 (EC| 2.7.11.25) (Mixed lineage kinase) (Leucine-zipper protein kinase) (ZPK) (Dual leucine zipper bearing kinase) (DLK) (MAPK-upstream kinase) (MUK) Length = 888 Score = 37.4 bits (85), Expect = 0.037 Identities = 35/124 (28%), Positives = 57/124 (45%), Gaps = 2/124 (1%) Frame = -3 Query: 615 SGHTGYMSPEYAMDGVFSMKSDIYSFGVMVLEIVTGKKNRGFYDAELDLNLLGYAWTLWK 436 +G +M+PE + S K DI+SFGV++ E++TG E+ + + +W Sbjct: 304 AGTVAWMAPEVIRNEPVSEKVDIWSFGVVLWELLTG---------EIPYKDVDSSAIIWG 354 Query: 435 EGRSTELLDEAMMGSSCDHSQVRRCIQVAL-LCVDMNPRNRPLMSSIVMMLATENA-TLP 262 G ++ L + SSC ++ L C + PRNRP I++ L +A L Sbjct: 355 VGSNSLHLP---VPSSCPDG-----FKILLRQCWNSKPRNRPSFRQILLHLDIASADVLS 406 Query: 261 EPNE 250 P E Sbjct: 407 TPQE 410
>M3K12_HUMAN (Q12852) Mitogen-activated protein kinase kinase kinase 12 (EC| 2.7.11.25) (Mixed lineage kinase) (Leucine-zipper protein kinase) (ZPK) (Dual leucine zipper bearing kinase) (DLK) (MAPK-upstream kinase) (MUK) Length = 859 Score = 37.4 bits (85), Expect = 0.037 Identities = 35/124 (28%), Positives = 57/124 (45%), Gaps = 2/124 (1%) Frame = -3 Query: 615 SGHTGYMSPEYAMDGVFSMKSDIYSFGVMVLEIVTGKKNRGFYDAELDLNLLGYAWTLWK 436 +G +M+PE + S K DI+SFGV++ E++TG E+ + + +W Sbjct: 271 AGTVAWMAPEVIRNEPVSEKVDIWSFGVVLWELLTG---------EIPYKDVDSSAIIWG 321 Query: 435 EGRSTELLDEAMMGSSCDHSQVRRCIQVAL-LCVDMNPRNRPLMSSIVMMLATENA-TLP 262 G ++ L + SSC ++ L C + PRNRP I++ L +A L Sbjct: 322 VGSNSLHLP---VPSSCPDG-----FKILLRQCWNSKPRNRPSFRQILLHLDIASADVLS 373 Query: 261 EPNE 250 P E Sbjct: 374 TPQE 377
>TMKL1_ARATH (P33543) Putative kinase-like protein TMKL1 precursor| Length = 674 Score = 37.4 bits (85), Expect = 0.037 Identities = 37/111 (33%), Positives = 55/111 (49%), Gaps = 5/111 (4%) Frame = -3 Query: 603 GYMSPEYAMDGVFSMKSDIYSFGVMVLEIVTGKK--NRGFYDAE-LDLNLLGYAWTLWKE 433 GY +PE + +SD+Y+FG+++LEI+ GKK G E +DL L A L E Sbjct: 541 GYKAPELHKMKKCNPRSDVYAFGILLLEILMGKKPGKSGRNGNEFVDLPSLVKAAVL--E 598 Query: 432 GRSTELLD-EAMMG-SSCDHSQVRRCIQVALLCVDMNPRNRPLMSSIVMML 286 + E+ D EAM G S + +++A+ C RP M +V L Sbjct: 599 ETTMEVFDLEAMKGIRSPMEEGLVHALKLAMGCCAPVTTVRPSMEEVVKQL 649
>SRK2_SPOLA (P42688) Tyrosine-protein kinase SRK2 (EC 2.7.10.2) (Fragment)| Length = 362 Score = 37.4 bits (85), Expect = 0.037 Identities = 29/104 (27%), Positives = 47/104 (45%), Gaps = 3/104 (2%) Frame = -3 Query: 600 YMSPEYAMDGVFSMKSDIYSFGVMVLEIVTGKK--NRGFYDAELDLNL-LGYAWTLWKEG 430 + +PE A+ FS+KSD++SFG+++ E+VT + G +AE+ NL GY Sbjct: 256 WTAPEAALFNRFSIKSDVWSFGILITELVTYGRIPYPGMSNAEVLQNLDKGYR------- 308 Query: 429 RSTELLDEAMMGSSCDHSQVRRCIQVALLCVDMNPRNRPLMSSI 298 C + Q+ L C NP +RP ++ Sbjct: 309 ------------MPCPVTTPESLYQIMLDCWKRNPADRPTFEAL 340
>INSR_AEDAE (Q93105) Insulin-like receptor precursor (EC 2.7.10.1) (MIR)| [Contains: Insulin-like receptor alpha chain; Insulin-like receptor beta chain] Length = 1390 Score = 37.0 bits (84), Expect = 0.048 Identities = 14/30 (46%), Positives = 23/30 (76%) Frame = -3 Query: 600 YMSPEYAMDGVFSMKSDIYSFGVMVLEIVT 511 +M+PE DG+FS SD++S+GV++ E+ T Sbjct: 1205 WMAPESLKDGIFSSSSDVFSYGVVLWEMAT 1234
>ROS_AVISU (P00529) Tyrosine-protein kinase transforming protein ros (EC| 2.7.10.1) Length = 402 Score = 37.0 bits (84), Expect = 0.048 Identities = 15/30 (50%), Positives = 24/30 (80%) Frame = -3 Query: 600 YMSPEYAMDGVFSMKSDIYSFGVMVLEIVT 511 +M+PE +DGVF+ SD+++FGV+V E +T Sbjct: 281 WMAPESLIDGVFTNHSDVWAFGVLVWETLT 310
>ROS_CHICK (P08941) Proto-oncogene tyrosine-protein kinase ROS precursor (EC| 2.7.10.1) (c-ros-1) Length = 2311 Score = 37.0 bits (84), Expect = 0.048 Identities = 15/30 (50%), Positives = 24/30 (80%) Frame = -3 Query: 600 YMSPEYAMDGVFSMKSDIYSFGVMVLEIVT 511 +M+PE +DGVF+ SD+++FGV+V E +T Sbjct: 2144 WMAPESLIDGVFTNHSDVWAFGVLVWETLT 2173
>YRK_CHICK (Q02977) Proto-oncogene tyrosine-protein kinase Yrk (EC 2.7.10.2)| (p60-Yrk) (Yes-related kinase) Length = 535 Score = 37.0 bits (84), Expect = 0.048 Identities = 14/30 (46%), Positives = 25/30 (83%) Frame = -3 Query: 600 YMSPEYAMDGVFSMKSDIYSFGVMVLEIVT 511 + +PE A+ G F++KSD++SFG+++ E+VT Sbjct: 430 WTAPEAALFGKFTIKSDVWSFGILLTELVT 459
>LRRK1_HUMAN (Q38SD2) Leucine-rich repeat serine/threonine-protein kinase 1 (EC| 2.7.11.1) Length = 2038 Score = 37.0 bits (84), Expect = 0.048 Identities = 30/109 (27%), Positives = 51/109 (46%) Frame = -3 Query: 612 GHTGYMSPEYAMDGVFSMKSDIYSFGVMVLEIVTGKKNRGFYDAELDLNLLGYAWTLWKE 433 G GY +PE V+ K D++S+G+++ E+++G++ L + L A L K Sbjct: 1449 GTPGYQAPEIRPRIVYDEKVDMFSYGMVLYELLSGQR------PALGHHQLQIAKKLSKG 1502 Query: 432 GRSTELLDEAMMGSSCDHSQVRRCIQVALLCVDMNPRNRPLMSSIVMML 286 R ++G + Q RR + + C D P RPL S+V + Sbjct: 1503 IR-------PVLGQP-EEVQFRRLQALMMECWDTKPEKRPLALSVVSQM 1543
>YES_XIPHE (P27447) Tyrosine-protein kinase Yes (EC 2.7.10.2) (p61-Yes)| Length = 543 Score = 36.6 bits (83), Expect = 0.062 Identities = 14/30 (46%), Positives = 25/30 (83%) Frame = -3 Query: 600 YMSPEYAMDGVFSMKSDIYSFGVMVLEIVT 511 + +PE A+ G F++KSD++SFG+++ E+VT Sbjct: 438 WTAPEAALYGRFTIKSDVWSFGILLTELVT 467
>YES_MOUSE (Q04736) Proto-oncogene tyrosine-protein kinase Yes (EC 2.7.10.2)| (p61-Yes) (c-Yes) Length = 540 Score = 36.6 bits (83), Expect = 0.062 Identities = 34/125 (27%), Positives = 55/125 (44%), Gaps = 3/125 (2%) Frame = -3 Query: 600 YMSPEYAMDGVFSMKSDIYSFGVMVLEIVTGKKNRGFYDAELDLNLLGYAWTLWKEGRST 421 + +PE A+ G F++KSD++SFG++ E+VT K R Y + + Sbjct: 435 WTAPEAALYGRFTIKSDVWSFGILQTELVT--KGRVPYPGMV----------------NR 476 Query: 420 ELLDEAMMG--SSCDHSQVRRCIQVALLCVDMNPRNRPLMSSIVMMLATENATLPEPN-E 250 E+L++ G C ++ LC +P RP I L + T EP + Sbjct: 477 EVLEQVERGYRMPCPQGCPESLHELMNLCWKKDPDERPTFEYIQSFL-EDYFTATEPQYQ 535 Query: 249 PGGNV 235 PG N+ Sbjct: 536 PGENL 540
>SRK1_SPOLA (P42686) Tyrosine-protein kinase isoform SRK1 (EC 2.7.10.2)| Length = 505 Score = 36.6 bits (83), Expect = 0.062 Identities = 18/39 (46%), Positives = 27/39 (69%), Gaps = 6/39 (15%) Frame = -3 Query: 609 HTG------YMSPEYAMDGVFSMKSDIYSFGVMVLEIVT 511 HTG + +PE AM F++KSD++SFGV++ EI+T Sbjct: 392 HTGAKFPIKWTAPEAAMYNRFTIKSDVWSFGVVLYEIIT 430
>BLK_HUMAN (P51451) Tyrosine-protein kinase BLK (EC 2.7.10.2) (B lymphocyte| kinase) (p55-BLK) Length = 504 Score = 36.6 bits (83), Expect = 0.062 Identities = 14/30 (46%), Positives = 25/30 (83%) Frame = -3 Query: 600 YMSPEYAMDGVFSMKSDIYSFGVMVLEIVT 511 + +PE GVF++K+D++SFGV+++E+VT Sbjct: 400 WTAPEAIHFGVFTIKADVWSFGVLLMEVVT 429
>M3K10_HUMAN (Q02779) Mitogen-activated protein kinase kinase kinase 10 (EC| 2.7.11.25) (Mixed lineage kinase 2) (Protein kinase MST) Length = 954 Score = 36.6 bits (83), Expect = 0.062 Identities = 15/38 (39%), Positives = 27/38 (71%) Frame = -3 Query: 618 SSGHTGYMSPEYAMDGVFSMKSDIYSFGVMVLEIVTGK 505 ++G +M+PE +FS SD++SFGV++ E++TG+ Sbjct: 263 AAGTYAWMAPEVIRLSLFSKSSDVWSFGVLLWELLTGE 300
>FYN_MOUSE (P39688) Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2)| (p59-Fyn) Length = 533 Score = 36.6 bits (83), Expect = 0.062 Identities = 14/30 (46%), Positives = 25/30 (83%) Frame = -3 Query: 600 YMSPEYAMDGVFSMKSDIYSFGVMVLEIVT 511 + +PE A+ G F++KSD++SFG+++ E+VT Sbjct: 428 WTAPEAALYGRFTIKSDVWSFGILLTELVT 457
>FYN_CHICK (Q05876) Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2)| (p59-Fyn) Length = 533 Score = 36.6 bits (83), Expect = 0.062 Identities = 14/30 (46%), Positives = 25/30 (83%) Frame = -3 Query: 600 YMSPEYAMDGVFSMKSDIYSFGVMVLEIVT 511 + +PE A+ G F++KSD++SFG+++ E+VT Sbjct: 428 WTAPEAALYGRFTIKSDVWSFGILLTELVT 457
>M3KL4_HUMAN (Q5TCX8) Mitogen-activated protein kinase kinase kinase (EC| 2.7.11.25) (Mixed lineage kinase 4) Length = 1036 Score = 36.6 bits (83), Expect = 0.062 Identities = 15/38 (39%), Positives = 27/38 (71%) Frame = -3 Query: 618 SSGHTGYMSPEYAMDGVFSMKSDIYSFGVMVLEIVTGK 505 ++G +M+PE +FS SDI+S+GV++ E++TG+ Sbjct: 304 TAGTYAWMAPEVIKSSLFSKGSDIWSYGVLLWELLTGE 341
>MIPR_LYMST (Q25410) Putative molluscan insulin-related peptide(s) receptor| precursor (EC 2.7.10.1) [Contains: Putative molluscan insulin-related peptide(s) receptor alpha chain; Putative molluscan insulin-related peptide(s) receptor beta chain] Length = 1607 Score = 36.6 bits (83), Expect = 0.062 Identities = 15/30 (50%), Positives = 24/30 (80%) Frame = -3 Query: 600 YMSPEYAMDGVFSMKSDIYSFGVMVLEIVT 511 +M+PE DGVF+ SD++S+GV++ E+VT Sbjct: 1216 WMAPESLKDGVFTSLSDVWSYGVVMWEMVT 1245
>YES_HUMAN (P07947) Proto-oncogene tyrosine-protein kinase Yes (EC 2.7.10.2)| (p61-Yes) (c-Yes) Length = 542 Score = 36.6 bits (83), Expect = 0.062 Identities = 34/125 (27%), Positives = 55/125 (44%), Gaps = 3/125 (2%) Frame = -3 Query: 600 YMSPEYAMDGVFSMKSDIYSFGVMVLEIVTGKKNRGFYDAELDLNLLGYAWTLWKEGRST 421 + +PE A+ G F++KSD++SFG++ E+VT K R Y + + Sbjct: 437 WTAPEAALYGRFTIKSDVWSFGILQTELVT--KGRVPYPGMV----------------NR 478 Query: 420 ELLDEAMMG--SSCDHSQVRRCIQVALLCVDMNPRNRPLMSSIVMMLATENATLPEPN-E 250 E+L++ G C ++ LC +P RP I L + T EP + Sbjct: 479 EVLEQVERGYRMPCPQGCPESLHELMNLCWKKDPDERPTFEYIQSFL-EDYFTATEPQYQ 537 Query: 249 PGGNV 235 PG N+ Sbjct: 538 PGENL 542
>MIL_AVIMH (P00531) Serine/threonine-protein kinase transforming protein mil| (EC 2.7.11.1) Length = 380 Score = 36.6 bits (83), Expect = 0.062 Identities = 36/157 (22%), Positives = 68/157 (43%), Gaps = 6/157 (3%) Frame = -3 Query: 615 SGHTGYMSPEYAM---DGVFSMKSDIYSFGVMVLEIVTGKKNRGFYDAELDLNLLGYAWT 445 +G +M+PE FS +SD+YS+G+++ E++TG+ + + Sbjct: 239 TGSILWMAPEVIRMQDSNPFSFQSDVYSYGIVLYELMTGELPYSHINNRDQI-------- 290 Query: 444 LWKEGRSTELLDEAMMGSSCDHSQVRRCIQVALLCVDMNPRNRPLMSSIVMMLATENATL 265 ++ GR D + + +C + R + C+ RPL I+ +A +L Sbjct: 291 IFMVGRGYASPDLSKLYKNCPKAMKR----LVADCLKKVREERPLFPQILSSIALLQHSL 346 Query: 264 PEPNEPGGNVGKSTSDGEL---SQTQSELTVTVTDTR 163 P+ + +S S+ L S T+ + T+T TR Sbjct: 347 PK-------INRSASEPSLHRASHTEDINSCTLTSTR 376
>KRAF1_DROME (P11346) Raf homolog serine/threonine-protein kinase dRAF-1 (EC| 2.7.11.1) (Protein pole-hole) Length = 739 Score = 36.6 bits (83), Expect = 0.062 Identities = 30/124 (24%), Positives = 57/124 (45%) Frame = -3 Query: 567 FSMKSDIYSFGVMVLEIVTGKKNRGFYDAELDLNLLGYAWTLWKEGRSTELLDEAMMGSS 388 +S +SD+Y+FG+++ E++ G + + L+ GR D + + S Sbjct: 605 YSFQSDVYAFGIVMYELLAECLPYGHISNKDQI--------LFMVGRGLLRPDMSQVRSD 656 Query: 387 CDHSQVRRCIQVALLCVDMNPRNRPLMSSIVMMLATENATLPEPNEPGGNVGKSTSDGEL 208 + R +A C+ P++RPL ++ ML TLP+ + +S S+ L Sbjct: 657 APQALKR----LAEDCIKYTPKDRPLFRPLLNMLENMLRTLPK-------IHRSASEPNL 705 Query: 207 SQTQ 196 +Q+Q Sbjct: 706 TQSQ 709
>FYN_XENLA (P13406) Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2)| (p59-Fyn) Length = 536 Score = 36.6 bits (83), Expect = 0.062 Identities = 14/30 (46%), Positives = 25/30 (83%) Frame = -3 Query: 600 YMSPEYAMDGVFSMKSDIYSFGVMVLEIVT 511 + +PE A+ G F++KSD++SFG+++ E+VT Sbjct: 431 WTAPEAALYGRFTIKSDVWSFGILLTELVT 460
>FYN_HUMAN (P06241) Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2)| (p59-Fyn) (Protooncogene Syn) (SLK) Length = 536 Score = 36.6 bits (83), Expect = 0.062 Identities = 14/30 (46%), Positives = 25/30 (83%) Frame = -3 Query: 600 YMSPEYAMDGVFSMKSDIYSFGVMVLEIVT 511 + +PE A+ G F++KSD++SFG+++ E+VT Sbjct: 431 WTAPEAALYGRFTIKSDVWSFGILLTELVT 460
>PKSC_STRCO (Q9S2C0) Serine/threonine protein kinase pksC (EC 2.7.11.1)| Length = 556 Score = 36.6 bits (83), Expect = 0.062 Identities = 15/36 (41%), Positives = 24/36 (66%) Frame = -3 Query: 612 GHTGYMSPEYAMDGVFSMKSDIYSFGVMVLEIVTGK 505 G Y+SPE A+ +SD+YS G+M+ ++VTG+ Sbjct: 191 GTPQYLSPEQALGRGVDARSDLYSVGIMLFQLVTGR 226
>JAK3_HUMAN (P52333) Tyrosine-protein kinase JAK3 (EC 2.7.10.2) (Janus kinase 3)| (JAK-3) (Leukocyte janus kinase) (L-JAK) Length = 1124 Score = 36.6 bits (83), Expect = 0.062 Identities = 29/103 (28%), Positives = 52/103 (50%), Gaps = 2/103 (1%) Frame = -3 Query: 600 YMSPEYAMDGVFSMKSDIYSFGVMVLEIVTGKKNRGFYDAELDLNLLGYAWTLWKEGRST 421 + +PE D +FS +SD++SFGV++ E+ T AE L ++G + R Sbjct: 993 WYAPESLSDNIFSRQSDVWSFGVVLYELFTYCDKSCSPSAEF-LRMMGCERDVPALCRLL 1051 Query: 420 ELLDEA--MMGSSCDHSQVRRCIQVALLCVDMNPRNRPLMSSI 298 ELL+E + ++V ++ LC +P++RP S++ Sbjct: 1052 ELLEEGQRLPAPPACPAEVHELMK---LCWAPSPQDRPSFSAL 1091
>FUZ7_USTMA (Q99078) Dual specificity protein kinase FUZ7 (EC 2.7.12.2)| Length = 435 Score = 36.6 bits (83), Expect = 0.062 Identities = 18/53 (33%), Positives = 31/53 (58%), Gaps = 4/53 (7%) Frame = -3 Query: 612 GHTGYMSPEYAMDGVFSMKSDIYSFGVMVLEIVTGK----KNRGFYDAELDLN 466 G + YMSPE +S+KSD++S GV ++++ G+ +N D++ D N Sbjct: 266 GTSTYMSPERIQGDQYSVKSDVWSLGVSIIDVALGRFPFAENEEDDDSDADNN 318
>YES_AVISY (P00527) Tyrosine-protein kinase transforming protein YES (EC| 2.7.10.2) (Fragment) Length = 528 Score = 36.6 bits (83), Expect = 0.062 Identities = 14/30 (46%), Positives = 25/30 (83%) Frame = -3 Query: 600 YMSPEYAMDGVFSMKSDIYSFGVMVLEIVT 511 + +PE A+ G F++KSD++SFG+++ E+VT Sbjct: 428 WTAPEAALYGRFTIKSDVWSFGILLTELVT 457
>PKN1_THETN (Q8R9T6) Probable serine/threonine-protein kinase Sps1 (EC| 2.7.11.1) Length = 625 Score = 36.6 bits (83), Expect = 0.062 Identities = 15/36 (41%), Positives = 23/36 (63%) Frame = -3 Query: 612 GHTGYMSPEYAMDGVFSMKSDIYSFGVMVLEIVTGK 505 G Y SPE A + ++DIYS G+++ E++TGK Sbjct: 172 GTAYYFSPEQAKGSIVDERTDIYSLGIVLFEMLTGK 207
>SWE1_YEAST (P32944) Mitosis inhibitor protein kinase SWE1 (EC 2.7.11.1)| Length = 819 Score = 36.2 bits (82), Expect = 0.081 Identities = 25/83 (30%), Positives = 41/83 (49%) Frame = -3 Query: 621 KSSGHTGYMSPEYAMDGVFSMKSDIYSFGVMVLEIVTGKKNRGFYDAELDLNLLGYAWTL 442 ++ G Y++PE D + K+DI+S G+M++EI A + L G A Sbjct: 612 ENEGDREYIAPEIISDCTYDYKADIFSLGLMIVEIA----------ANVVLPDNGNA--- 658 Query: 441 WKEGRSTELLDEAMMGSSCDHSQ 373 W + RS +L D + S+ HS+ Sbjct: 659 WHKLRSGDLSDAGRLSSTDIHSE 681
>FGR_MOUSE (P14234) Proto-oncogene tyrosine-protein kinase FGR (EC 2.7.10.2)| (P55-FGR) (C-FGR) Length = 517 Score = 36.2 bits (82), Expect = 0.081 Identities = 13/30 (43%), Positives = 25/30 (83%) Frame = -3 Query: 600 YMSPEYAMDGVFSMKSDIYSFGVMVLEIVT 511 + +PE A+ G F++KSD++SFG+++ E++T Sbjct: 412 WTAPEAALFGRFTVKSDVWSFGILLTELIT 441
>M3K11_HUMAN (Q16584) Mitogen-activated protein kinase kinase kinase 11 (EC| 2.7.11.25) (Mixed lineage kinase 3) (Src-homology 3 domain-containing proline-rich kinase) Length = 847 Score = 36.2 bits (82), Expect = 0.081 Identities = 15/38 (39%), Positives = 26/38 (68%) Frame = -3 Query: 618 SSGHTGYMSPEYAMDGVFSMKSDIYSFGVMVLEIVTGK 505 ++G +M+PE FS SD++SFGV++ E++TG+ Sbjct: 282 AAGTYAWMAPEVIKASTFSKGSDVWSFGVLLWELLTGE 319
>YES_XENLA (P10936) Tyrosine-protein kinase Yes (EC 2.7.10.2) (p61-Yes)| Length = 536 Score = 36.2 bits (82), Expect = 0.081 Identities = 33/125 (26%), Positives = 55/125 (44%), Gaps = 3/125 (2%) Frame = -3 Query: 600 YMSPEYAMDGVFSMKSDIYSFGVMVLEIVTGKKNRGFYDAELDLNLLGYAWTLWKEGRST 421 + +PE A+ G F++KSD++SFG+++ E+V K R Y + + Sbjct: 431 WTAPEAALYGRFTIKSDVWSFGILLTELVA--KGRVPYPGMV----------------NR 472 Query: 420 ELLDEAMMG--SSCDHSQVRRCIQVALLCVDMNPRNRPLMSSIVMMLATENATLPEPN-E 250 E+L++ G C ++ LC +P RP I L + T EP + Sbjct: 473 EVLEQVERGYRMPCPQRCPESLHELMKLCWKKDPDERPTFEYIQSFL-EDYFTATEPQYQ 531 Query: 249 PGGNV 235 PG N+ Sbjct: 532 PGDNL 536
>NEK9_XENLA (Q7ZZC8) Serine/threonine-protein kinase Nek9 (EC 2.7.11.1)| (NimA-related protein kinase 9) (XNek9) (Nercc1 kinase) Length = 944 Score = 36.2 bits (82), Expect = 0.081 Identities = 29/103 (28%), Positives = 46/103 (44%), Gaps = 1/103 (0%) Frame = -3 Query: 600 YMSPEYAMDGVFSMKSDIYSFGVMVLEIVTGKKNRGFYDAELDLNL-LGYAWTLWKEGRS 424 YMSPE +S KSDI++ G ++ E++T + +DA LNL + W G Sbjct: 199 YMSPEICQGVKYSFKSDIWAVGCVLYELLTLTRT---FDATNPLNLCVKIVQGNWAVG-- 253 Query: 423 TELLDEAMMGSSCDHSQVRRCIQVALLCVDMNPRNRPLMSSIV 295 LD + + I+V C++ +P RP I+ Sbjct: 254 ---LDNTV--------YTQELIEVVHACLEQDPEKRPTADEIL 285
>FGR_HUMAN (P09769) Proto-oncogene tyrosine-protein kinase FGR (EC 2.7.10.2)| (P55-FGR) (C-FGR) Length = 529 Score = 36.2 bits (82), Expect = 0.081 Identities = 13/30 (43%), Positives = 25/30 (83%) Frame = -3 Query: 600 YMSPEYAMDGVFSMKSDIYSFGVMVLEIVT 511 + +PE A+ G F++KSD++SFG+++ E++T Sbjct: 424 WTAPEAALFGRFTIKSDVWSFGILLTELIT 453
>INSR_DROME (P09208) Insulin-like receptor precursor (EC 2.7.10.1) (DIR) (DInr)| (dIRH) [Contains: Insulin-like receptor alpha subunit; Insulin-like receptor beta 1 subunit; Insulin-like receptor beta 2 subunit] Length = 2144 Score = 36.2 bits (82), Expect = 0.081 Identities = 15/30 (50%), Positives = 22/30 (73%) Frame = -3 Query: 600 YMSPEYAMDGVFSMKSDIYSFGVMVLEIVT 511 +M PE DGV+S SD++SFGV++ E+ T Sbjct: 1562 WMPPESLRDGVYSSASDVFSFGVVLWEMAT 1591
>PKN2_MYXXA (P54736) Serine/threonine-protein kinase pkn2 (EC 2.7.11.1)| Length = 830 Score = 35.8 bits (81), Expect = 0.11 Identities = 18/51 (35%), Positives = 28/51 (54%) Frame = -3 Query: 612 GHTGYMSPEYAMDGVFSMKSDIYSFGVMVLEIVTGKKNRGFYDAELDLNLL 460 G Y+SPE A+ +SD+YSFGV+ +++G+ +D L N L Sbjct: 179 GTPEYLSPEQAVGAKVDTRSDLYSFGVLTYRVLSGRLP---FDGPLPRNFL 226
>SRK3_SPOLA (P42689) Tyrosine-protein kinase SRK3 (EC 2.7.10.2) (Fragment)| Length = 334 Score = 35.8 bits (81), Expect = 0.11 Identities = 15/30 (50%), Positives = 24/30 (80%) Frame = -3 Query: 600 YMSPEYAMDGVFSMKSDIYSFGVMVLEIVT 511 + +PE A+ F++KSD++SFGV++ EIVT Sbjct: 228 WTAPEAALYNRFTIKSDVWSFGVLISEIVT 257
>PKN6_MYXXA (P54738) Serine/threonine-protein kinase pkn6 (EC 2.7.11.1)| Length = 710 Score = 35.8 bits (81), Expect = 0.11 Identities = 16/51 (31%), Positives = 29/51 (56%) Frame = -3 Query: 612 GHTGYMSPEYAMDGVFSMKSDIYSFGVMVLEIVTGKKNRGFYDAELDLNLL 460 G YM PE + D+Y+ GV++ E++TGK+ +DA D++++ Sbjct: 181 GKVAYMPPEQLQAKAMDRRVDVYALGVVLYELLTGKRP---FDATTDVSVM 228
>JAK3_RAT (Q63272) Tyrosine-protein kinase JAK3 (EC 2.7.10.2) (Janus kinase 3)| (JAK-3) Length = 1100 Score = 35.8 bits (81), Expect = 0.11 Identities = 32/108 (29%), Positives = 53/108 (49%), Gaps = 7/108 (6%) Frame = -3 Query: 600 YMSPEYAMDGVFSMKSDIYSFGVMVLEIVTGKKNRGFYDAELDLNLLGYAWTLWKEG--- 430 + +PE D +FS +SD++SFGV++ E+ T E L ++G +EG Sbjct: 989 WYAPESLSDNIFSRQSDVWSFGVVLYELFTYSDKSCSPSTEF-LRMIGPE----REGSPL 1043 Query: 429 -RSTELLDEAMM---GSSCDHSQVRRCIQVALLCVDMNPRNRPLMSSI 298 ELL E S+C ++V+ +Q LC NP++RP ++ Sbjct: 1044 CHLLELLAEGRRLPPPSTCP-TEVQELMQ---LCWSPNPQDRPAFDTL 1087
>YPS7_CAEEL (Q20085) Putative serine/threonine-protein kinase F35H8.7 (EC| 2.7.11.1) Length = 468 Score = 35.8 bits (81), Expect = 0.11 Identities = 31/109 (28%), Positives = 53/109 (48%) Frame = -3 Query: 621 KSSGHTGYMSPEYAMDGVFSMKSDIYSFGVMVLEIVTGKKNRGFYDAELDLNLLGYAWTL 442 +S G Y S E A++G S+ SDI+SFG+ +LE+ T +++L Y T Sbjct: 263 QSEGDGKYCSKE-AINGTLSIFSDIFSFGISILEVGT------------NIHLPSYG-TG 308 Query: 441 WKEGRSTELLDEAMMGSSCDHSQVRRCIQVALLCVDMNPRNRPLMSSIV 295 W+ R E+ +E + S ++R ++ + D P RP S ++ Sbjct: 309 WEPIRKWEIPEEILEPMS---DELRELVKQMM---DKAPTRRPTCSELM 351
>M3K9_HUMAN (P80192) Mitogen-activated protein kinase kinase kinase 9 (EC| 2.7.11.25) (Mixed lineage kinase 1) Length = 1104 Score = 35.4 bits (80), Expect = 0.14 Identities = 14/38 (36%), Positives = 27/38 (71%) Frame = -3 Query: 618 SSGHTGYMSPEYAMDGVFSMKSDIYSFGVMVLEIVTGK 505 ++G +M+PE +FS SD++S+GV++ E++TG+ Sbjct: 309 AAGTYAWMAPEVIRASMFSKGSDVWSYGVLLWELLTGE 346
>HCK_MOUSE (P08103) Tyrosine-protein kinase HCK (EC 2.7.10.2)| (p56-HCK/p59-HCK) (Hemopoietic cell kinase) (B-cell/myeloid kinase) (BMK) Length = 523 Score = 35.4 bits (80), Expect = 0.14 Identities = 14/30 (46%), Positives = 24/30 (80%) Frame = -3 Query: 600 YMSPEYAMDGVFSMKSDIYSFGVMVLEIVT 511 + +PE G F++KSD++SFG++++EIVT Sbjct: 420 WTAPEAINFGSFTIKSDVWSFGILLMEIVT 449
>HCK_RAT (P50545) Tyrosine-protein kinase HCK (EC 2.7.10.2) (p56-HCK)| (Hemopoietic cell kinase) Length = 502 Score = 35.4 bits (80), Expect = 0.14 Identities = 14/30 (46%), Positives = 24/30 (80%) Frame = -3 Query: 600 YMSPEYAMDGVFSMKSDIYSFGVMVLEIVT 511 + +PE G F++KSD++SFG++++EIVT Sbjct: 399 WTAPEAINFGSFTIKSDVWSFGILLMEIVT 428
>HCK_HUMAN (P08631) Tyrosine-protein kinase HCK (EC 2.7.10.2)| (p59-HCK/p60-HCK) (Hemopoietic cell kinase) Length = 525 Score = 35.4 bits (80), Expect = 0.14 Identities = 14/30 (46%), Positives = 24/30 (80%) Frame = -3 Query: 600 YMSPEYAMDGVFSMKSDIYSFGVMVLEIVT 511 + +PE G F++KSD++SFG++++EIVT Sbjct: 422 WTAPEAINFGSFTIKSDVWSFGILLMEIVT 451
>MKK1_YEAST (P32490) MAP kinase kinase MKK1/SSP32 (EC 2.7.12.2)| Length = 508 Score = 35.4 bits (80), Expect = 0.14 Identities = 20/70 (28%), Positives = 36/70 (51%) Frame = -3 Query: 615 SGHTGYMSPEYAMDGVFSMKSDIYSFGVMVLEIVTGKKNRGFYDAELDLNLLGYAWTLWK 436 +G + YM+PE +S+ SD++S G+ +LE+ GK ++ N+ + +W Sbjct: 383 TGTSFYMAPERIQGQPYSVTSDVWSLGLTILEVANGKFPCS--SEKMAANIAPFELLMWI 440 Query: 435 EGRSTELLDE 406 + EL DE Sbjct: 441 LTFTPELKDE 450
>PKNB_LACLA (Q9CEF5) Probable serine/threonine-protein kinase pknB (EC| 2.7.11.1) Length = 627 Score = 35.4 bits (80), Expect = 0.14 Identities = 14/36 (38%), Positives = 25/36 (69%) Frame = -3 Query: 612 GHTGYMSPEYAMDGVFSMKSDIYSFGVMVLEIVTGK 505 G Y+SPE A +++SDIY+ G+++ E++TG+ Sbjct: 174 GSVHYLSPEQARGSNATVQSDIYAIGIILFELLTGQ 209
>SRC_MOUSE (P05480) Neuronal proto-oncogene tyrosine-protein kinase Src (EC| 2.7.10.2) (p60-Src) (c-Src) (pp60c-src) Length = 540 Score = 35.0 bits (79), Expect = 0.18 Identities = 13/30 (43%), Positives = 24/30 (80%) Frame = -3 Query: 600 YMSPEYAMDGVFSMKSDIYSFGVMVLEIVT 511 + +PE A+ G F++KSD++SFG+++ E+ T Sbjct: 435 WTAPEAALYGRFTIKSDVWSFGILLTELTT 464
>FLT3_MOUSE (Q00342) FL cytokine receptor precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor flk-2) (Fetal liver kinase 2) (Tyrosine-protein kinase FLT3) Length = 992 Score = 35.0 bits (79), Expect = 0.18 Identities = 11/28 (39%), Positives = 24/28 (85%) Frame = -3 Query: 600 YMSPEYAMDGVFSMKSDIYSFGVMVLEI 517 +M+PE +G++++KSD++S+G+++ EI Sbjct: 857 WMAPESLFEGIYTIKSDVWSYGILLWEI 884
>SRC_RSVSE (P63185) Tyrosine-protein kinase transforming protein Src (EC| 2.7.10.2) (p60-Src) (v-Src) (pp60v-src) Length = 525 Score = 35.0 bits (79), Expect = 0.18 Identities = 13/30 (43%), Positives = 24/30 (80%) Frame = -3 Query: 600 YMSPEYAMDGVFSMKSDIYSFGVMVLEIVT 511 + +PE A+ G F++KSD++SFG+++ E+ T Sbjct: 427 WTAPEAALYGRFTIKSDVWSFGILLTELTT 456
>SRC_RSVSA (P00524) Tyrosine-protein kinase transforming protein Src (EC| 2.7.10.2) (p60-Src) (v-Src) (pp60v-src) Length = 525 Score = 35.0 bits (79), Expect = 0.18 Identities = 13/30 (43%), Positives = 24/30 (80%) Frame = -3 Query: 600 YMSPEYAMDGVFSMKSDIYSFGVMVLEIVT 511 + +PE A+ G F++KSD++SFG+++ E+ T Sbjct: 427 WTAPEAALYGRFTIKSDVWSFGILLTELTT 456
>SRC_RSVP (P00526) Tyrosine-protein kinase transforming protein Src (EC| 2.7.10.2) (p60-Src) (v-Src) (pp60v-src) Length = 525 Score = 35.0 bits (79), Expect = 0.18 Identities = 13/30 (43%), Positives = 24/30 (80%) Frame = -3 Query: 600 YMSPEYAMDGVFSMKSDIYSFGVMVLEIVT 511 + +PE A+ G F++KSD++SFG+++ E+ T Sbjct: 427 WTAPEAALYGRFTIKSDVWSFGILLTELTT 456
>SRC_RSVH1 (P25020) Tyrosine-protein kinase transforming protein Src (EC| 2.7.10.2) (p60-Src) (v-Src) (pp60v-src) Length = 525 Score = 35.0 bits (79), Expect = 0.18 Identities = 13/30 (43%), Positives = 24/30 (80%) Frame = -3 Query: 600 YMSPEYAMDGVFSMKSDIYSFGVMVLEIVT 511 + +PE A+ G F++KSD++SFG+++ E+ T Sbjct: 427 WTAPEAALYGRFTIKSDVWSFGILLTELTT 456
>SRC_AVISR (P00525) Tyrosine-protein kinase transforming protein Src (EC| 2.7.10.2) (p60-Src) (v-Src) (pp60v-src) Length = 525 Score = 35.0 bits (79), Expect = 0.18 Identities = 13/30 (43%), Positives = 24/30 (80%) Frame = -3 Query: 600 YMSPEYAMDGVFSMKSDIYSFGVMVLEIVT 511 + +PE A+ G F++KSD++SFG+++ E+ T Sbjct: 427 WTAPEAALYGRFTIKSDVWSFGILLTELTT 456
>STK_HYDAT (P17713) Tyrosine-protein kinase STK (EC 2.7.10.2) (P57-STK)| Length = 509 Score = 35.0 bits (79), Expect = 0.18 Identities = 14/30 (46%), Positives = 24/30 (80%) Frame = -3 Query: 600 YMSPEYAMDGVFSMKSDIYSFGVMVLEIVT 511 + +PE A+ F++KSD++SFG+++ EIVT Sbjct: 402 WTAPEAALYNRFTIKSDVWSFGILMAEIVT 431
>FLT3_HUMAN (P36888) FL cytokine receptor precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor FLT3) (Stem cell tyrosine kinase 1) (STK-1) (CD135 antigen) Length = 993 Score = 35.0 bits (79), Expect = 0.18 Identities = 11/28 (39%), Positives = 24/28 (85%) Frame = -3 Query: 600 YMSPEYAMDGVFSMKSDIYSFGVMVLEI 517 +M+PE +G++++KSD++S+G+++ EI Sbjct: 854 WMAPESLFEGIYTIKSDVWSYGILLWEI 881
>ALK_MOUSE (P97793) ALK tyrosine kinase receptor precursor (EC 2.7.10.1)| (Anaplastic lymphoma kinase) (CD246 antigen) Length = 1621 Score = 35.0 bits (79), Expect = 0.18 Identities = 14/28 (50%), Positives = 22/28 (78%) Frame = -3 Query: 600 YMSPEYAMDGVFSMKSDIYSFGVMVLEI 517 +M PE M+G+F+ K+D +SFGV++ EI Sbjct: 1299 WMPPEAFMEGIFTSKTDTWSFGVLLWEI 1326
>LCK_SAISC (Q95KR7) Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2)| (p56-LCK) (Lymphocyte cell-specific protein-tyrosine kinase) Length = 508 Score = 35.0 bits (79), Expect = 0.18 Identities = 14/30 (46%), Positives = 23/30 (76%) Frame = -3 Query: 600 YMSPEYAMDGVFSMKSDIYSFGVMVLEIVT 511 + +PE G F++KSD++SFG+++ EIVT Sbjct: 405 WTAPEAINYGTFTIKSDVWSFGILMTEIVT 434
>LCK_MOUSE (P06240) Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2)| (p56-LCK) (Lymphocyte cell-specific protein-tyrosine kinase) (LSK) Length = 508 Score = 35.0 bits (79), Expect = 0.18 Identities = 14/30 (46%), Positives = 23/30 (76%) Frame = -3 Query: 600 YMSPEYAMDGVFSMKSDIYSFGVMVLEIVT 511 + +PE G F++KSD++SFG+++ EIVT Sbjct: 405 WTAPEAINYGTFTIKSDVWSFGILLTEIVT 434
>LCK_HUMAN (P06239) Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2)| (p56-LCK) (Lymphocyte cell-specific protein-tyrosine kinase) (LSK) (T cell-specific protein-tyrosine kinase) Length = 508 Score = 35.0 bits (79), Expect = 0.18 Identities = 14/30 (46%), Positives = 23/30 (76%) Frame = -3 Query: 600 YMSPEYAMDGVFSMKSDIYSFGVMVLEIVT 511 + +PE G F++KSD++SFG+++ EIVT Sbjct: 405 WTAPEAINYGTFTIKSDVWSFGILLTEIVT 434
>LCK_AOTNA (Q5PXS1) Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2)| (p56-LCK) (Lymphocyte cell-specific protein-tyrosine kinase) Length = 508 Score = 35.0 bits (79), Expect = 0.18 Identities = 14/30 (46%), Positives = 23/30 (76%) Frame = -3 Query: 600 YMSPEYAMDGVFSMKSDIYSFGVMVLEIVT 511 + +PE G F++KSD++SFG+++ EIVT Sbjct: 405 WTAPEAINYGTFTIKSDVWSFGILLTEIVT 434
>YES_CANFA (Q28923) Proto-oncogene tyrosine-protein kinase Yes (EC 2.7.10.2)| (p61-Yes) (c-Yes) Length = 538 Score = 35.0 bits (79), Expect = 0.18 Identities = 33/125 (26%), Positives = 54/125 (43%), Gaps = 3/125 (2%) Frame = -3 Query: 600 YMSPEYAMDGVFSMKSDIYSFGVMVLEIVTGKKNRGFYDAELDLNLLGYAWTLWKEGRST 421 + +PE A+ G F++KSD++SFG++ E+ T K R Y + + Sbjct: 433 WTAPEAALYGRFTIKSDVWSFGILQTELTT--KGRVPYPGMV----------------NR 474 Query: 420 ELLDEAMMG--SSCDHSQVRRCIQVALLCVDMNPRNRPLMSSIVMMLATENATLPEPN-E 250 E+L++ G C ++ LC +P RP I L + T EP + Sbjct: 475 EVLEQVERGYRMPCPQGCPESLHELMNLCWKKDPDERPTFEYIQSFL-EDYFTAAEPQYQ 533 Query: 249 PGGNV 235 PG N+ Sbjct: 534 PGENL 538
>RIPK3_RAT (Q9Z2P5) Receptor-interacting serine/threonine-protein kinase 3 (EC| 2.7.11.1) (RIP-like protein kinase 3) (Receptor-interacting protein 3) (RIP-3) (Homocysteine respondent protein HCYP2) Length = 478 Score = 35.0 bits (79), Expect = 0.18 Identities = 17/40 (42%), Positives = 25/40 (62%), Gaps = 1/40 (2%) Frame = -3 Query: 618 SSGHTGYMSPEYA-MDGVFSMKSDIYSFGVMVLEIVTGKK 502 S G Y++PE DG S SD+YSFGV+V ++ G++ Sbjct: 182 SGGTLAYLAPELLDNDGKASKASDVYSFGVLVWTVLAGRE 221
>SRC_RAT (Q9WUD9) Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2)| (p60-Src) (c-Src) (pp60c-src) Length = 535 Score = 35.0 bits (79), Expect = 0.18 Identities = 13/30 (43%), Positives = 24/30 (80%) Frame = -3 Query: 600 YMSPEYAMDGVFSMKSDIYSFGVMVLEIVT 511 + +PE A+ G F++KSD++SFG+++ E+ T Sbjct: 430 WTAPEAALYGRFTIKSDVWSFGILLTELTT 459
>SRC_HUMAN (P12931) Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2)| (p60-Src) (c-Src) (pp60c-src) Length = 535 Score = 35.0 bits (79), Expect = 0.18 Identities = 13/30 (43%), Positives = 24/30 (80%) Frame = -3 Query: 600 YMSPEYAMDGVFSMKSDIYSFGVMVLEIVT 511 + +PE A+ G F++KSD++SFG+++ E+ T Sbjct: 430 WTAPEAALYGRFTIKSDVWSFGILLTELTT 459
>PKNB_BIFLO (Q8G6P9) Probable serine/threonine-protein kinase pknB (EC| 2.7.11.1) Length = 690 Score = 35.0 bits (79), Expect = 0.18 Identities = 15/36 (41%), Positives = 23/36 (63%) Frame = -3 Query: 612 GHTGYMSPEYAMDGVFSMKSDIYSFGVMVLEIVTGK 505 G Y+SPE A M+SD+YS G ++ E++TG+ Sbjct: 186 GTAQYLSPEQARGETVDMRSDLYSAGCVLYEMLTGR 221
>LCK_CHICK (P42683) Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2)| (Protein-tyrosine kinase C-TKL) (p56tk1) Length = 507 Score = 35.0 bits (79), Expect = 0.18 Identities = 14/30 (46%), Positives = 23/30 (76%) Frame = -3 Query: 600 YMSPEYAMDGVFSMKSDIYSFGVMVLEIVT 511 + +PE G F++KSD++SFG+++ EIVT Sbjct: 404 WTAPEAINYGTFTIKSDVWSFGILLTEIVT 433
>ALK_HUMAN (Q9UM73) ALK tyrosine kinase receptor precursor (EC 2.7.10.1)| (Anaplastic lymphoma kinase) (CD246 antigen) Length = 1620 Score = 35.0 bits (79), Expect = 0.18 Identities = 14/28 (50%), Positives = 22/28 (78%) Frame = -3 Query: 600 YMSPEYAMDGVFSMKSDIYSFGVMVLEI 517 +M PE M+G+F+ K+D +SFGV++ EI Sbjct: 1295 WMPPEAFMEGIFTSKTDTWSFGVLLWEI 1322
>FGFR1_RAT (Q04589) Basic fibroblast growth factor receptor 1 precursor (EC| 2.7.10.1) (FGFR-1) (bFGF-R) (MFR) Length = 822 Score = 35.0 bits (79), Expect = 0.18 Identities = 18/44 (40%), Positives = 28/44 (63%), Gaps = 2/44 (4%) Frame = -3 Query: 600 YMSPEYAMDGVFSMKSDIYSFGVMVLEIVT--GKKNRGFYDAEL 475 +M+PE D +++ +SD++SFGV++ EI T G N G EL Sbjct: 666 WMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPNPGVPVEEL 709
>SRC2_XENLA (P13116) Tyrosine-protein kinase Src-2 (EC 2.7.10.2) (p60-Src-2)| Length = 531 Score = 35.0 bits (79), Expect = 0.18 Identities = 13/30 (43%), Positives = 24/30 (80%) Frame = -3 Query: 600 YMSPEYAMDGVFSMKSDIYSFGVMVLEIVT 511 + +PE A+ G F++KSD++SFG+++ E+ T Sbjct: 426 WTAPEAALYGRFTIKSDVWSFGILLTELTT 455
>SRC1_XENLA (P13115) Tyrosine-protein kinase Src-1 (EC 2.7.10.2) (p60-Src-1)| Length = 531 Score = 35.0 bits (79), Expect = 0.18 Identities = 13/30 (43%), Positives = 24/30 (80%) Frame = -3 Query: 600 YMSPEYAMDGVFSMKSDIYSFGVMVLEIVT 511 + +PE A+ G F++KSD++SFG+++ E+ T Sbjct: 426 WTAPEAALYGRFTIKSDVWSFGILLTELTT 455
>SRK4_SPOLA (P42690) Tyrosine-protein kinase isoform SRK4 (EC 2.7.10.2)| Length = 506 Score = 35.0 bits (79), Expect = 0.18 Identities = 13/30 (43%), Positives = 24/30 (80%) Frame = -3 Query: 600 YMSPEYAMDGVFSMKSDIYSFGVMVLEIVT 511 + +PE AM F++KSD++SFG+++ E++T Sbjct: 401 WTAPEAAMYSRFTIKSDVWSFGIVLYEVIT 430
>SRC_AVIST (P14085) Tyrosine-protein kinase transforming protein Src (EC| 2.7.10.2) (p60-Src) (v-Src) (pp60v-src) Length = 556 Score = 35.0 bits (79), Expect = 0.18 Identities = 13/30 (43%), Positives = 24/30 (80%) Frame = -3 Query: 600 YMSPEYAMDGVFSMKSDIYSFGVMVLEIVT 511 + +PE A+ G F++KSD++SFG+++ E+ T Sbjct: 427 WTAPEAALYGRFTIKSDVWSFGILLTELTT 456
>SRC_AVISS (P14084) Tyrosine-protein kinase transforming protein Src (EC| 2.7.10.2) (p60-Src) (v-Src) (pp60v-src) Length = 567 Score = 35.0 bits (79), Expect = 0.18 Identities = 13/30 (43%), Positives = 24/30 (80%) Frame = -3 Query: 600 YMSPEYAMDGVFSMKSDIYSFGVMVLEIVT 511 + +PE A+ G F++KSD++SFG+++ E+ T Sbjct: 427 WTAPEAALYGRFTIKSDVWSFGILLTELTT 456
>SRC_RSVPA (P31693) Tyrosine-protein kinase transforming protein Src (EC| 2.7.10.2) (p60-Src) (v-Src) (pp60v-src) Length = 522 Score = 35.0 bits (79), Expect = 0.18 Identities = 13/30 (43%), Positives = 24/30 (80%) Frame = -3 Query: 600 YMSPEYAMDGVFSMKSDIYSFGVMVLEIVT 511 + +PE A+ G F++KSD++SFG+++ E+ T Sbjct: 424 WTAPEAALYGRFTIKSDVWSFGILLTELTT 453
>SRC_CHICK (P00523) Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2)| (p60-Src) (c-Src) (pp60c-src) Length = 532 Score = 35.0 bits (79), Expect = 0.18 Identities = 13/30 (43%), Positives = 24/30 (80%) Frame = -3 Query: 600 YMSPEYAMDGVFSMKSDIYSFGVMVLEIVT 511 + +PE A+ G F++KSD++SFG+++ E+ T Sbjct: 427 WTAPEAALYGRFTIKSDVWSFGILLTELTT 456
>SRC_AVIS2 (P15054) Tyrosine-protein kinase transforming protein Src (EC| 2.7.10.2) (p60-Src) (v-Src) (pp60v-src) Length = 586 Score = 35.0 bits (79), Expect = 0.18 Identities = 13/30 (43%), Positives = 24/30 (80%) Frame = -3 Query: 600 YMSPEYAMDGVFSMKSDIYSFGVMVLEIVT 511 + +PE A+ G F++KSD++SFG+++ E+ T Sbjct: 427 WTAPEAALYGRFTIKSDVWSFGILLTELTT 456
>PTK7_CHICK (Q91048) Tyrosine-protein kinase-like 7 precursor (Kinase-like| protein) Length = 1051 Score = 35.0 bits (79), Expect = 0.18 Identities = 14/30 (46%), Positives = 22/30 (73%) Frame = -3 Query: 600 YMSPEYAMDGVFSMKSDIYSFGVMVLEIVT 511 +M PE ++ FS KSD++SFGV++ E+ T Sbjct: 953 WMPPEAVLEDEFSTKSDVWSFGVLMWEVFT 982
>YR831_MIMIV (Q7T6Y2) Putative serine/threonine-protein kinase/receptor R831| precursor (EC 2.7.11.1) Length = 1624 Score = 34.7 bits (78), Expect = 0.24 Identities = 27/110 (24%), Positives = 50/110 (45%), Gaps = 2/110 (1%) Frame = -3 Query: 600 YMSPEYAMDGVFSMKSDIYSFGVMVLEIVTGKKNRGFYDAELDLNLLGYAWTLWKEGRST 421 + +PE + K+D++SFGV++ E++TGK + + N + + + + GR Sbjct: 1526 WTAPEVIRGEKYCEKADVFSFGVVMWEVLTGK------EPFAECNFMKVSLDILEGGR-- 1577 Query: 420 ELLDEAMMGSSCDHSQVRRCIQVALLCVDMNPRNRPLMSSIV--MMLATE 277 ++ S C H + + C RP M+ +V +ML TE Sbjct: 1578 -----PIIPSDCPHEFAK----LIKKCWHAKAHKRPTMTEVVQQLMLITE 1618 Score = 33.5 bits (75), Expect = 0.53 Identities = 34/152 (22%), Positives = 71/152 (46%), Gaps = 10/152 (6%) Frame = -3 Query: 612 GHTGYMSPEYAMDG--VFSMKSDIYSFGVMVLEIVTGKK-NRGFYDAELDLNLLGYAWTL 442 G +++PE D V + +D+YSFG+++ E++T ++ +G A + ++++ Sbjct: 947 GTIHWIAPEILNDSTEVDYILADVYSFGIILWELLTREQPYKGMTPAAIAVSVI------ 1000 Query: 441 WKEGRSTELLDEAMMGSSCDHSQVRRCIQVALLCVDMNPRNRPLMSSIVMMLA-----TE 277 ++G + DEA+ S ++ I + C + RP I+ L+ + Sbjct: 1001 -RDGMRPPISDEAVTAHSIEY------IDLIKQCWHSDTIIRPTFLEIMTRLSNILGDSS 1053 Query: 276 NAT--LPEPNEPGGNVGKSTSDGELSQTQSEL 187 N T + G +GKS +D + S ++S + Sbjct: 1054 NMTSGTSSSSLSSGGIGKSITDSKSSNSRSSV 1085
>CTR1_ARATH (Q05609) Serine/threonine-protein kinase CTR1 (EC 2.7.11.1)| Length = 821 Score = 34.7 bits (78), Expect = 0.24 Identities = 34/128 (26%), Positives = 54/128 (42%), Gaps = 6/128 (4%) Frame = -3 Query: 618 SSGHTGYMSPEYAMDGVFSMKSDIYSFGVMVLEIVTGKKNRGFYDAELDLNLLGYAWTLW 439 ++G +M+PE D + KSD+YSFGV++ E+ T L W Sbjct: 711 AAGTPEWMAPEVLRDEPSNEKSDVYSFGVILWELAT----------------LQQPW--- 751 Query: 438 KEGRSTELLDEAMMGSSCDHSQVRRCI--QVALL---CVDMNPRNRPLMSSIVMML-ATE 277 G A +G C ++ R + QVA + C P RP ++I+ +L Sbjct: 752 --GNLNPAQVVAAVGFKCKRLEIPRNLNPQVAAIIEGCWTNEPWKRPSFATIMDLLRPLI 809 Query: 276 NATLPEPN 253 + +P PN Sbjct: 810 KSAVPPPN 817
>TOPK_BRARE (Q6DHU8) T-lymphokine-activated killer cell-originated protein| kinase homolog (EC 2.7.12.2) (PDZ-binding kinase) Length = 339 Score = 34.7 bits (78), Expect = 0.24 Identities = 30/120 (25%), Positives = 57/120 (47%), Gaps = 12/120 (10%) Frame = -3 Query: 576 DGVFSMKSDIYSFGVMVLEIVT------------GKKNRGFYDAELDLNLLGYAWTLWKE 433 DGV + K+DI+++G+ + E++T G ++ E D + Y ++ Sbjct: 223 DGVITDKADIFAYGLTLWEMMTLSVPHLEMLDTEGDEDDDDESFEEDFDEDAY----YER 278 Query: 432 GRSTELLDEAMMGSSCDHSQVRRCIQVALLCVDMNPRNRPLMSSIVMMLATENATLPEPN 253 S LD +G S +R +++ LC + +P+ RP + IV +L + N+ L + N Sbjct: 279 LGSRPALDAVTLGGS-----YQRMVELFCLCTEEDPQKRPSAAHIVQVLES-NSQLSKQN 332
>VGFR1_MOUSE (P35969) Vascular endothelial growth factor receptor 1 precursor (EC| 2.7.10.1) (VEGFR-1) (Tyrosine-protein kinase receptor FLT) (FLT-1) (Embryonic receptor kinase 2) Length = 1333 Score = 34.7 bits (78), Expect = 0.24 Identities = 14/28 (50%), Positives = 22/28 (78%) Frame = -3 Query: 600 YMSPEYAMDGVFSMKSDIYSFGVMVLEI 517 +M+PE D V+S KSD++S+GV++ EI Sbjct: 1065 WMAPESIFDKVYSTKSDVWSYGVLLWEI 1092
>UFO_MOUSE (Q00993) Tyrosine-protein kinase receptor UFO precursor (EC 2.7.10.1)| (Adhesion-related kinase) Length = 888 Score = 34.7 bits (78), Expect = 0.24 Identities = 34/125 (27%), Positives = 52/125 (41%), Gaps = 7/125 (5%) Frame = -3 Query: 600 YMSPEYAMDGVFSMKSDIYSFGVMVLEIVT-------GKKNRGFYDAELDLNLLGYAWTL 442 +++ E D V++ KSD++SFGV + EI T G +N YD N L Sbjct: 709 WIAIESLADRVYTSKSDVWSFGVTMWEIATRGQTPYPGVENSEIYDYLRQGNRL------ 762 Query: 441 WKEGRSTELLDEAMMGSSCDHSQVRRCIQVALLCVDMNPRNRPLMSSIVMMLATENATLP 262 + + LD +S + R C ++NPR+RP + + L LP Sbjct: 763 ---KQPVDFLDGL-------YSLMSR-------CWELNPRDRPSFAELREDLENTLKALP 805 Query: 261 EPNEP 247 EP Sbjct: 806 PAQEP 810
>ROR2_MOUSE (Q9Z138) Tyrosine-protein kinase transmembrane receptor ROR2| precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase, receptor-related 2) (mROR2) Length = 944 Score = 34.7 bits (78), Expect = 0.24 Identities = 15/28 (53%), Positives = 22/28 (78%) Frame = -3 Query: 600 YMSPEYAMDGVFSMKSDIYSFGVMVLEI 517 +MSPE M G FS+ SDI+S+GV++ E+ Sbjct: 658 WMSPEAVMYGKFSIDSDIWSYGVVLWEV 685
>PTK7_HUMAN (Q13308) Tyrosine-protein kinase-like 7 precursor (Colon carcinoma| kinase 4) (CCK-4) Length = 1070 Score = 34.7 bits (78), Expect = 0.24 Identities = 14/30 (46%), Positives = 23/30 (76%) Frame = -3 Query: 600 YMSPEYAMDGVFSMKSDIYSFGVMVLEIVT 511 +MSPE ++G FS KSD+++ GV++ E+ T Sbjct: 972 WMSPEAILEGDFSTKSDVWASGVLMWEVFT 1001
>LTK_MOUSE (P08923) Leukocyte tyrosine kinase receptor precursor (EC 2.7.10.1)| Length = 888 Score = 34.7 bits (78), Expect = 0.24 Identities = 35/128 (27%), Positives = 56/128 (43%), Gaps = 9/128 (7%) Frame = -3 Query: 600 YMSPEYAMDGVFSMKSDIYSFGVMVLEIVTGKKNRGFYDAELDLNLLGYAWTLWKEGRST 421 +M PE ++G+F+ K+D +SFGV++ EI + LGY + + Sbjct: 685 WMPPEALLEGLFTSKTDSWSFGVLLWEIFS----------------LGY--MPYPGHTNQ 726 Query: 420 ELLDEAMMGSSCDHSQVRRC----IQVALLCVDMNPRNRPLMSSIV--MMLATENATL-- 265 E+LD G+ D R C ++ C P RP SI+ + T++ + Sbjct: 727 EVLDFIATGNRMD--PPRNCPGPVYRIMTQCWQHQPELRPDFGSILERIQYCTQDPDVLN 784 Query: 264 -PEPNEPG 244 P P EPG Sbjct: 785 SPLPMEPG 792
>ARAF_PIG (O19004) A-Raf proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (A-Raf-1) Length = 606 Score = 34.7 bits (78), Expect = 0.24 Identities = 28/126 (22%), Positives = 58/126 (46%) Frame = -3 Query: 567 FSMKSDIYSFGVMVLEIVTGKKNRGFYDAELDLNLLGYAWTLWKEGRSTELLDEAMMGSS 388 +S +SD+Y++GV++ E++TG + + ++ GR D + + S+ Sbjct: 486 YSFQSDVYAYGVVLYELMTGSLPYSHIGSRDQI--------IFMVGRGYLSPDLSKISSN 537 Query: 387 CDHSQVRRCIQVALLCVDMNPRNRPLMSSIVMMLATENATLPEPNEPGGNVGKSTSDGEL 208 C + +RR + C+ RPL I+ + +LP+ + +S S+ L Sbjct: 538 CPKA-MRRLLSD---CLKFQREERPLFPQILATIELLQRSLPK-------IERSASEPSL 586 Query: 207 SQTQSE 190 +TQ++ Sbjct: 587 HRTQAD 592
>RAF1_CHICK (P05625) RAF proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (RAF-1) (C-RAF) (MIL proto-oncogene serine/threonine-protein kinase) (C-MIL) Length = 647 Score = 34.7 bits (78), Expect = 0.24 Identities = 35/157 (22%), Positives = 67/157 (42%), Gaps = 6/157 (3%) Frame = -3 Query: 615 SGHTGYMSPEYAM---DGVFSMKSDIYSFGVMVLEIVTGKKNRGFYDAELDLNLLGYAWT 445 +G +M+PE FS +SD+YS+G+++ E++TG+ + + Sbjct: 506 TGSILWMAPEVIRMQDSNPFSFQSDVYSYGIVLYELMTGELPYSHINNRDQI-------- 557 Query: 444 LWKEGRSTELLDEAMMGSSCDHSQVRRCIQVALLCVDMNPRNRPLMSSIVMMLATENATL 265 ++ GR D + + +C + R + C+ RPL I+ + +L Sbjct: 558 IFMVGRGYASPDLSKLYKNCPKAMKR----LVADCLKKVREERPLFPQILSSIELLQHSL 613 Query: 264 PEPNEPGGNVGKSTSDGEL---SQTQSELTVTVTDTR 163 P+ + +S S+ L S T+ + T+T TR Sbjct: 614 PK-------INRSASEPSLHRASHTEDINSCTLTSTR 643
>FGR_FSVGR (P00544) Tyrosine-protein kinase transforming protein Fgr (EC| 2.7.10.2) Length = 545 Score = 34.7 bits (78), Expect = 0.24 Identities = 12/30 (40%), Positives = 25/30 (83%) Frame = -3 Query: 600 YMSPEYAMDGVFSMKSDIYSFGVMVLEIVT 511 + +PE A+ G F++KSD++SFG+++ E+++ Sbjct: 447 WTAPEAALFGRFTIKSDVWSFGILLTELIS 476
>VGFR1_RAT (P53767) Vascular endothelial growth factor receptor 1 precursor (EC| 2.7.10.1) (VEGFR-1) (Tyrosine-protein kinase receptor FLT) (FLT-1) Length = 1336 Score = 34.7 bits (78), Expect = 0.24 Identities = 14/28 (50%), Positives = 22/28 (78%) Frame = -3 Query: 600 YMSPEYAMDGVFSMKSDIYSFGVMVLEI 517 +M+PE D V+S KSD++S+GV++ EI Sbjct: 1065 WMAPESIFDKVYSTKSDVWSYGVLLWEI 1092
>LYN_RAT (Q07014) Tyrosine-protein kinase Lyn (EC 2.7.10.2)| Length = 511 Score = 34.7 bits (78), Expect = 0.24 Identities = 14/30 (46%), Positives = 23/30 (76%) Frame = -3 Query: 600 YMSPEYAMDGVFSMKSDIYSFGVMVLEIVT 511 + +PE G F++KSD++SFG+++ EIVT Sbjct: 408 WTAPEAINFGCFTIKSDVWSFGILLYEIVT 437
>LYN_MOUSE (P25911) Tyrosine-protein kinase Lyn (EC 2.7.10.2)| Length = 511 Score = 34.7 bits (78), Expect = 0.24 Identities = 14/30 (46%), Positives = 23/30 (76%) Frame = -3 Query: 600 YMSPEYAMDGVFSMKSDIYSFGVMVLEIVT 511 + +PE G F++KSD++SFG+++ EIVT Sbjct: 408 WTAPEAINFGCFTIKSDVWSFGILLYEIVT 437
>LYN_HUMAN (P07948) Tyrosine-protein kinase Lyn (EC 2.7.10.2)| Length = 511 Score = 34.7 bits (78), Expect = 0.24 Identities = 14/30 (46%), Positives = 23/30 (76%) Frame = -3 Query: 600 YMSPEYAMDGVFSMKSDIYSFGVMVLEIVT 511 + +PE G F++KSD++SFG+++ EIVT Sbjct: 408 WTAPEAINFGCFTIKSDVWSFGILLYEIVT 437
>ROR1_MOUSE (Q9Z139) Tyrosine-protein kinase transmembrane receptor ROR1| precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase, receptor-related 1) (mROR1) Length = 937 Score = 34.7 bits (78), Expect = 0.24 Identities = 19/35 (54%), Positives = 23/35 (65%) Frame = -3 Query: 621 KSSGHTGYMSPEYAMDGVFSMKSDIYSFGVMVLEI 517 KSS +M PE M G FS SDI+SFGV++ EI Sbjct: 651 KSSLPIRWMPPEAIMYGKFSSDSDIWSFGVVLWEI 685
>NEK7_MOUSE (Q9ES74) Serine/threonine-protein kinase Nek7 (EC 2.7.11.1)| (NimA-related protein kinase 7) Length = 302 Score = 34.3 bits (77), Expect = 0.31 Identities = 24/96 (25%), Positives = 42/96 (43%) Frame = -3 Query: 600 YMSPEYAMDGVFSMKSDIYSFGVMVLEIVTGKKNRGFYDAELDLNLLGYAWTLWKEGRST 421 YMSPE + ++ KSDI+S G ++ E+ A L G L+ + Sbjct: 202 YMSPERIHENGYNFKSDIWSLGCLLYEM-----------AALQSPFYGDKMNLYSLCKKI 250 Query: 420 ELLDEAMMGSSCDHSQVRRCIQVALLCVDMNPRNRP 313 E D + S ++R+ + + C++ +P RP Sbjct: 251 EQCDYPPLPSDHYSEELRQLVNI---CINPDPEKRP 283
>FRK_HUMAN (P42685) Tyrosine-protein kinase FRK (EC 2.7.10.2) (Nuclear| tyrosine protein kinase RAK) Length = 505 Score = 34.3 bits (77), Expect = 0.31 Identities = 13/30 (43%), Positives = 22/30 (73%) Frame = -3 Query: 600 YMSPEYAMDGVFSMKSDIYSFGVMVLEIVT 511 + +PE FS+KSD++SFG+++ EI+T Sbjct: 399 WTAPEAIRSNKFSIKSDVWSFGILLYEIIT 428
>FGFR3_HUMAN (P22607) Fibroblast growth factor receptor 3 precursor (EC| 2.7.10.1) (FGFR-3) (CD333 antigen) Length = 806 Score = 34.3 bits (77), Expect = 0.31 Identities = 14/30 (46%), Positives = 23/30 (76%) Frame = -3 Query: 600 YMSPEYAMDGVFSMKSDIYSFGVMVLEIVT 511 +M+PE D V++ +SD++SFGV++ EI T Sbjct: 660 WMAPEALFDRVYTHQSDVWSFGVLLWEIFT 689
>FGFR2_XENLA (Q03364) Fibroblast growth factor receptor 2 precursor (EC| 2.7.10.1) (FGFR-2) Length = 813 Score = 34.3 bits (77), Expect = 0.31 Identities = 14/30 (46%), Positives = 23/30 (76%) Frame = -3 Query: 600 YMSPEYAMDGVFSMKSDIYSFGVMVLEIVT 511 +M+PE D V++ +SD++SFGV++ EI T Sbjct: 659 WMAPEALFDRVYTHQSDVWSFGVLMWEIFT 688
>CEK2_CHICK (P18460) Tyrosine kinase receptor CEK2 precursor (EC 2.7.10.1)| Length = 806 Score = 34.3 bits (77), Expect = 0.31 Identities = 14/30 (46%), Positives = 23/30 (76%) Frame = -3 Query: 600 YMSPEYAMDGVFSMKSDIYSFGVMVLEIVT 511 +M+PE D V++ +SD++SFGV++ EI T Sbjct: 654 WMAPEALFDRVYTHQSDVWSFGVLLWEIFT 683
>UFO_HUMAN (P30530) Tyrosine-protein kinase receptor UFO precursor (EC 2.7.10.1)| (AXL oncogene) Length = 887 Score = 34.3 bits (77), Expect = 0.31 Identities = 33/122 (27%), Positives = 54/122 (44%), Gaps = 4/122 (3%) Frame = -3 Query: 600 YMSPEYAMDGVFSMKSDIYSFGVMVLEIVTGKKNRGFYDAELDLNLLGYAWTLWKEGRST 421 +++ E D V++ KSD++SFGV + EI T RG T + ++ Sbjct: 708 WIAIESLADRVYTSKSDVWSFGVTMWEIAT----RG--------------QTPYPGVENS 749 Query: 420 ELLDEAMMGSSCDHSQVRRCIQ--VALL--CVDMNPRNRPLMSSIVMMLATENATLPEPN 253 E+ D G+ Q C+ AL+ C ++NP++RP + + L LP Sbjct: 750 EIYDYLRQGNRL--KQPADCLDGLYALMSRCWELNPQDRPSFTELREDLENTLKALPPAQ 807 Query: 252 EP 247 EP Sbjct: 808 EP 809
>RET_HUMAN (P07949) Proto-oncogene tyrosine-protein kinase receptor ret| precursor (EC 2.7.10.1) (C-ret) Length = 1114 Score = 34.3 bits (77), Expect = 0.31 Identities = 29/103 (28%), Positives = 44/103 (42%), Gaps = 2/103 (1%) Frame = -3 Query: 600 YMSPEYAMDGVFSMKSDIYSFGVMVLEIVT--GKKNRGFYDAELDLNLLGYAWTLWKEGR 427 +M+ E D +++ +SD++SFGV++ EIVT G G L + L K G Sbjct: 917 WMAIESLFDHIYTTQSDVWSFGVLLWEIVTLGGNPYPGIPPERL--------FNLLKTGH 968 Query: 426 STELLDEAMMGSSCDHSQVRRCIQVALLCVDMNPRNRPLMSSI 298 E D +C R +Q C P RP+ + I Sbjct: 969 RMERPD------NCSEEMYRLMLQ----CWKQEPDKRPVFADI 1001
>CEK3_CHICK (P18461) Tyrosine kinase receptor CEK3 precursor (EC 2.7.10.1)| Length = 823 Score = 34.3 bits (77), Expect = 0.31 Identities = 14/30 (46%), Positives = 23/30 (76%) Frame = -3 Query: 600 YMSPEYAMDGVFSMKSDIYSFGVMVLEIVT 511 +M+PE D V++ +SD++SFGV++ EI T Sbjct: 671 WMAPEALFDRVYTHQSDVWSFGVLMWEIFT 700
>SRC42_DROME (Q9V9J3) Tyrosine-protein kinase Src42A (EC 2.7.10.2) (Dsrc41)| Length = 517 Score = 34.3 bits (77), Expect = 0.31 Identities = 14/30 (46%), Positives = 23/30 (76%) Frame = -3 Query: 600 YMSPEYAMDGVFSMKSDIYSFGVMVLEIVT 511 + +PE A FS+KSD++SFG+++ E+VT Sbjct: 412 WTAPEAANYSKFSIKSDVWSFGILLTELVT 441
>FGFR2_MOUSE (P21803) Fibroblast growth factor receptor 2 precursor (EC| 2.7.10.1) (FGFR-2) (Keratinocyte growth factor receptor) Length = 821 Score = 34.3 bits (77), Expect = 0.31 Identities = 14/30 (46%), Positives = 23/30 (76%) Frame = -3 Query: 600 YMSPEYAMDGVFSMKSDIYSFGVMVLEIVT 511 +M+PE D V++ +SD++SFGV++ EI T Sbjct: 669 WMAPEALFDRVYTHQSDVWSFGVLMWEIFT 698
>FGFR2_HUMAN (P21802) Fibroblast growth factor receptor 2 precursor (EC| 2.7.10.1) (FGFR-2) (Keratinocyte growth factor receptor 2) (CD332 antigen) Length = 821 Score = 34.3 bits (77), Expect = 0.31 Identities = 14/30 (46%), Positives = 23/30 (76%) Frame = -3 Query: 600 YMSPEYAMDGVFSMKSDIYSFGVMVLEIVT 511 +M+PE D V++ +SD++SFGV++ EI T Sbjct: 669 WMAPEALFDRVYTHQSDVWSFGVLMWEIFT 698
>BLK_MOUSE (P16277) Tyrosine-protein kinase BLK (EC 2.7.10.2) (B lymphocyte| kinase) (p55-BLK) Length = 498 Score = 34.3 bits (77), Expect = 0.31 Identities = 14/30 (46%), Positives = 24/30 (80%) Frame = -3 Query: 600 YMSPEYAMDGVFSMKSDIYSFGVMVLEIVT 511 + +PE GVF++K+D++SFGV+++ IVT Sbjct: 394 WTAPEAIHFGVFTIKADVWSFGVLLMVIVT 423
>VGFR1_HUMAN (P17948) Vascular endothelial growth factor receptor 1 precursor (EC| 2.7.10.1) (VEGFR-1) (Vascular permeability factor receptor) (Tyrosine-protein kinase receptor FLT) (Flt-1) (Tyrosine-protein kinase FRT) (Fms-like tyrosine kinase 1) Length = 1338 Score = 34.3 bits (77), Expect = 0.31 Identities = 13/28 (46%), Positives = 22/28 (78%) Frame = -3 Query: 600 YMSPEYAMDGVFSMKSDIYSFGVMVLEI 517 +M+PE D ++S KSD++S+GV++ EI Sbjct: 1065 WMAPESIFDKIYSTKSDVWSYGVLLWEI 1092
>RET_MOUSE (P35546) Proto-oncogene tyrosine-protein kinase receptor ret| precursor (EC 2.7.10.1) (C-ret) Length = 1115 Score = 34.3 bits (77), Expect = 0.31 Identities = 29/103 (28%), Positives = 44/103 (42%), Gaps = 2/103 (1%) Frame = -3 Query: 600 YMSPEYAMDGVFSMKSDIYSFGVMVLEIVT--GKKNRGFYDAELDLNLLGYAWTLWKEGR 427 +M+ E D +++ +SD++SFGV++ EIVT G G L + L K G Sbjct: 918 WMAIESLFDHIYTTQSDVWSFGVLLWEIVTLGGNPYPGIPPERL--------FNLLKTGH 969 Query: 426 STELLDEAMMGSSCDHSQVRRCIQVALLCVDMNPRNRPLMSSI 298 E D +C R +Q C P RP+ + I Sbjct: 970 RMERPD------NCSEEMYRLMLQ----CWKQEPDKRPVFADI 1002
>PKNB_MYCLE (P54744) Probable serine/threonine-protein kinase pknB (EC| 2.7.11.1) Length = 622 Score = 34.3 bits (77), Expect = 0.31 Identities = 15/36 (41%), Positives = 22/36 (61%) Frame = -3 Query: 612 GHTGYMSPEYAMDGVFSMKSDIYSFGVMVLEIVTGK 505 G Y+SPE A +SD+YS G ++ EI+TG+ Sbjct: 177 GTAQYLSPEQARGDSVDARSDVYSLGCVLYEILTGE 212
>FGFR3_MOUSE (Q61851) Fibroblast growth factor receptor 3 precursor (EC| 2.7.10.1) (FGFR-3) (Heparin-binding growth factor receptor) Length = 801 Score = 34.3 bits (77), Expect = 0.31 Identities = 14/30 (46%), Positives = 23/30 (76%) Frame = -3 Query: 600 YMSPEYAMDGVFSMKSDIYSFGVMVLEIVT 511 +M+PE D V++ +SD++SFGV++ EI T Sbjct: 654 WMAPEALFDRVYTHQSDVWSFGVLLWEIFT 683
>ARAF_HUMAN (P10398) A-Raf proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (A-raf-1) (Proto-oncogene Pks) Length = 606 Score = 34.3 bits (77), Expect = 0.31 Identities = 30/127 (23%), Positives = 60/127 (47%), Gaps = 1/127 (0%) Frame = -3 Query: 567 FSMKSDIYSFGVMVLEIVTGKKNRGFYDAELDLNLLGYA-WTLWKEGRSTELLDEAMMGS 391 +S +SD+Y++GV++ E++TG L + +G ++ GR D + + S Sbjct: 486 YSFQSDVYAYGVVLYELMTG---------SLPYSHIGCRDQIIFMVGRGYLSPDLSKISS 536 Query: 390 SCDHSQVRRCIQVALLCVDMNPRNRPLMSSIVMMLATENATLPEPNEPGGNVGKSTSDGE 211 +C + +RR + C+ RPL I+ + +LP+ + +S S+ Sbjct: 537 NCPKA-MRRLLSD---CLKFQREERPLFPQILATIELLQRSLPK-------IERSASEPS 585 Query: 210 LSQTQSE 190 L +TQ++ Sbjct: 586 LHRTQAD 592
>VGFR2_HUMAN (P35968) Vascular endothelial growth factor receptor 2 precursor (EC| 2.7.10.1) (VEGFR-2) (Kinase insert domain receptor) (Protein-tyrosine kinase receptor Flk-1) (CD309 antigen) Length = 1356 Score = 33.9 bits (76), Expect = 0.40 Identities = 13/28 (46%), Positives = 23/28 (82%) Frame = -3 Query: 600 YMSPEYAMDGVFSMKSDIYSFGVMVLEI 517 +M+PE D V++++SD++SFGV++ EI Sbjct: 1071 WMAPETIFDRVYTIQSDVWSFGVLLWEI 1098
>ILPR_BRALA (O02466) Insulin-like peptide receptor precursor (EC 2.7.10.1) (ILP| receptor) [Contains: Insulin-like peptide receptor alpha chain; Insulin-like peptide receptor beta chain] Length = 1363 Score = 33.9 bits (76), Expect = 0.40 Identities = 14/30 (46%), Positives = 23/30 (76%) Frame = -3 Query: 600 YMSPEYAMDGVFSMKSDIYSFGVMVLEIVT 511 +MSPE GVF+ +SD++S+GV++ E+ T Sbjct: 1191 WMSPESLKVGVFTSQSDVWSYGVVLWEMAT 1220
>FGFR1_CHICK (P21804) Basic fibroblast growth factor receptor 1 precursor (EC| 2.7.10.1) Length = 819 Score = 33.9 bits (76), Expect = 0.40 Identities = 13/30 (43%), Positives = 23/30 (76%) Frame = -3 Query: 600 YMSPEYAMDGVFSMKSDIYSFGVMVLEIVT 511 +M+PE D +++ +SD++SFGV++ EI T Sbjct: 664 WMAPEALFDRIYTHQSDVWSFGVLLWEIFT 693
>BRAF1_CHICK (Q04982) B-Raf proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (Rmil serine/threonine-protein kinase) (c-Rmil) Length = 806 Score = 33.9 bits (76), Expect = 0.40 Identities = 37/152 (24%), Positives = 63/152 (41%), Gaps = 8/152 (5%) Frame = -3 Query: 615 SGHTGYMSPEYAM---DGVFSMKSDIYSFGVMVLEIVTGKKNRGFYDAELDLNLLGYAWT 445 SG +M+PE +S +SD+Y+FG+++ E++TG+ N+ Sbjct: 654 SGSILWMAPEVIRMQDKNPYSFQSDVYAFGIVLYELMTGQLPYS--------NINNRDQI 705 Query: 444 LWKEGRSTELLDEAMMGSSCDHSQVRRCIQVALLCVDMNPRNRPLMSSIVMMLATENATL 265 ++ GR D + + S+C + R + C+ RPL I+ + +L Sbjct: 706 IFMVGRGYLSPDLSKVRSNCPKAMKRLMAE----CLKKKRDERPLFPQILASIELLARSL 761 Query: 264 PE----PNEPGGN-VGKSTSDGELSQTQSELT 184 P+ +EP N G T D L S T Sbjct: 762 PKIHRSASEPSLNRAGFQTEDFSLYACASPKT 793
>SPK1_DUGTI (P42687) Tyrosine-protein kinase SPK-1 (EC 2.7.10.2)| Length = 497 Score = 33.9 bits (76), Expect = 0.40 Identities = 13/30 (43%), Positives = 23/30 (76%) Frame = -3 Query: 600 YMSPEYAMDGVFSMKSDIYSFGVMVLEIVT 511 + +PE A VF+ KSD++S+G+++ EI+T Sbjct: 385 WTAPEAAKSKVFTSKSDVWSYGIVMFEILT 414
>NEK7_HUMAN (Q8TDX7) Serine/threonine-protein kinase Nek7 (EC 2.7.11.1)| (NimA-related protein kinase 7) Length = 302 Score = 33.9 bits (76), Expect = 0.40 Identities = 25/96 (26%), Positives = 42/96 (43%) Frame = -3 Query: 600 YMSPEYAMDGVFSMKSDIYSFGVMVLEIVTGKKNRGFYDAELDLNLLGYAWTLWKEGRST 421 YMSPE + ++ KSDI+S G ++ E+ A L G L+ + Sbjct: 202 YMSPERIHENGYNFKSDIWSLGCLLYEM-----------AALQSPFYGDKMNLYSLCKKI 250 Query: 420 ELLDEAMMGSSCDHSQVRRCIQVALLCVDMNPRNRP 313 E D + S ++R Q+ +C++ +P RP Sbjct: 251 EQCDYPPLPSDHYSEELR---QLVNMCINPDPEKRP 283
>BRAF1_HUMAN (P15056) B-Raf proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (p94) (v-Raf murine sarcoma viral oncogene homolog B1) Length = 766 Score = 33.9 bits (76), Expect = 0.40 Identities = 37/152 (24%), Positives = 63/152 (41%), Gaps = 8/152 (5%) Frame = -3 Query: 615 SGHTGYMSPEYAM---DGVFSMKSDIYSFGVMVLEIVTGKKNRGFYDAELDLNLLGYAWT 445 SG +M+PE +S +SD+Y+FG+++ E++TG+ N+ Sbjct: 614 SGSILWMAPEVIRMQDKNPYSFQSDVYAFGIVLYELMTGQLPYS--------NINNRDQI 665 Query: 444 LWKEGRSTELLDEAMMGSSCDHSQVRRCIQVALLCVDMNPRNRPLMSSIVMMLATENATL 265 ++ GR D + + S+C + R + C+ RPL I+ + +L Sbjct: 666 IFMVGRGYLSPDLSKVRSNCPKAMKRLMAE----CLKKKRDERPLFPQILASIELLARSL 721 Query: 264 PE----PNEPGGN-VGKSTSDGELSQTQSELT 184 P+ +EP N G T D L S T Sbjct: 722 PKIHRSASEPSLNRAGFQTEDFSLYACASPKT 753
>VGFR2_MOUSE (P35918) Vascular endothelial growth factor receptor 2 precursor (EC| 2.7.10.1) (VEGFR-2) (Protein-tyrosine kinase receptor flk-1) (Fetal liver kinase 1) (Kinase NYK) Length = 1367 Score = 33.9 bits (76), Expect = 0.40 Identities = 13/28 (46%), Positives = 23/28 (82%) Frame = -3 Query: 600 YMSPEYAMDGVFSMKSDIYSFGVMVLEI 517 +M+PE D V++++SD++SFGV++ EI Sbjct: 1069 WMAPETIFDRVYTIQSDVWSFGVLLWEI 1096
>RMIL_AVEVR (P27966) Serine/threonine-protein kinase transforming protein Rmil| (EC 2.7.11.1) Length = 450 Score = 33.9 bits (76), Expect = 0.40 Identities = 37/152 (24%), Positives = 63/152 (41%), Gaps = 8/152 (5%) Frame = -3 Query: 615 SGHTGYMSPEYAM---DGVFSMKSDIYSFGVMVLEIVTGKKNRGFYDAELDLNLLGYAWT 445 SG +M+PE +S +SD+Y+FG+++ E++TG+ N+ Sbjct: 240 SGSILWMAPEVIRMQDKNPYSFQSDVYAFGIVLYELMTGQLPYS--------NINNRDQI 291 Query: 444 LWKEGRSTELLDEAMMGSSCDHSQVRRCIQVALLCVDMNPRNRPLMSSIVMMLATENATL 265 ++ GR D + + S+C + R + C+ RPL I+ + +L Sbjct: 292 IFMVGRGYLSPDLSKVRSNCPKAMKRLMAE----CLKKKRDERPLFPQILASIELLARSL 347 Query: 264 PE----PNEPGGN-VGKSTSDGELSQTQSELT 184 P+ +EP N G T D L S T Sbjct: 348 PKIHRSASEPSLNRAGFQTEDFSLYACASPKT 379
>PKN1_CORGL (Q8NU98) Probable serine/threonine protein kinase pknB (EC| 2.7.11.1) Length = 646 Score = 33.9 bits (76), Expect = 0.40 Identities = 16/36 (44%), Positives = 22/36 (61%) Frame = -3 Query: 612 GHTGYMSPEYAMDGVFSMKSDIYSFGVMVLEIVTGK 505 G Y+SPE A +SDIY+ G ++ E+VTGK Sbjct: 176 GTAQYLSPEQARGKPADARSDIYATGCVMYELVTGK 211
>LIMK1_DROME (Q8IR79) LIM domain kinase 1 (EC 2.7.11.1) (LIMK-1) (dLIMK)| Length = 1257 Score = 33.9 bits (76), Expect = 0.40 Identities = 27/109 (24%), Positives = 50/109 (45%) Frame = -3 Query: 612 GHTGYMSPEYAMDGVFSMKSDIYSFGVMVLEIVTGKKNRGFYDAELDLNLLGYAWTLWKE 433 G+ +M+PE + K D++SFG+M+ EI+ G +A+ D ++L ++ Sbjct: 594 GNPYWMAPEMMKGLKYDEKVDVFSFGIMLCEII------GRVEADPDFMPRNSDFSLNQQ 647 Query: 432 GRSTELLDEAMMGSSCDHSQVRRCIQVALLCVDMNPRNRPLMSSIVMML 286 + + C V+ VA +C D+NP RP ++ + L Sbjct: 648 EFREKFC------AQCPEPFVK----VAFVCCDLNPDMRPCFETLHVWL 686
>IKKB_DROME (Q9VEZ5) Inhibitor of nuclear factor kappa B kinase beta subunit| (EC 2.7.11.1) (DmIKK-beta) (Immune response deficient protein 5) (IKK-like protein) (Lipopolysaccharide-activated kinase) (DLAK) (Cactus kinase IKK) Length = 751 Score = 33.9 bits (76), Expect = 0.40 Identities = 14/36 (38%), Positives = 23/36 (63%) Frame = -3 Query: 612 GHTGYMSPEYAMDGVFSMKSDIYSFGVMVLEIVTGK 505 G Y +PE +G ++ D++SFGV+ E+VTG+ Sbjct: 224 GTRHYYAPEVVENGFYNSTVDLWSFGVIAYELVTGE 259
>FGFR1_MOUSE (P16092) Basic fibroblast growth factor receptor 1 precursor (EC| 2.7.10.1) (FGFR-1) (bFGF-R) (MFR) Length = 822 Score = 33.9 bits (76), Expect = 0.40 Identities = 13/30 (43%), Positives = 23/30 (76%) Frame = -3 Query: 600 YMSPEYAMDGVFSMKSDIYSFGVMVLEIVT 511 +M+PE D +++ +SD++SFGV++ EI T Sbjct: 666 WMAPEALFDRIYTHQSDVWSFGVLLWEIFT 695
>FGFR1_HUMAN (P11362) Basic fibroblast growth factor receptor 1 precursor (EC| 2.7.10.1) (FGFR-1) (bFGF-R) (Fms-like tyrosine kinase 2) (c-fgr) (CD331 antigen) Length = 822 Score = 33.9 bits (76), Expect = 0.40 Identities = 13/30 (43%), Positives = 23/30 (76%) Frame = -3 Query: 600 YMSPEYAMDGVFSMKSDIYSFGVMVLEIVT 511 +M+PE D +++ +SD++SFGV++ EI T Sbjct: 666 WMAPEALFDRIYTHQSDVWSFGVLLWEIFT 695
>BRAF1_MOUSE (P28028) B-Raf proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (Fragment) Length = 328 Score = 33.9 bits (76), Expect = 0.40 Identities = 37/152 (24%), Positives = 63/152 (41%), Gaps = 8/152 (5%) Frame = -3 Query: 615 SGHTGYMSPEYAM---DGVFSMKSDIYSFGVMVLEIVTGKKNRGFYDAELDLNLLGYAWT 445 SG +M+PE +S +SD+Y+FG+++ E++TG+ N+ Sbjct: 176 SGSILWMAPEVIRMQDKNPYSFQSDVYAFGIVLYELMTGQLPYS--------NINNRDQI 227 Query: 444 LWKEGRSTELLDEAMMGSSCDHSQVRRCIQVALLCVDMNPRNRPLMSSIVMMLATENATL 265 ++ GR D + + S+C + R + C+ RPL I+ + +L Sbjct: 228 IFMVGRGYLSPDLSKVRSNCPKAMKRLMAE----CLKKKRDERPLFPQILASIELLARSL 283 Query: 264 PE----PNEPGGN-VGKSTSDGELSQTQSELT 184 P+ +EP N G T D L S T Sbjct: 284 PKIHRSASEPSLNRAGFQTEDFSLYACASPKT 315
>BRAF1_COTJA (P34908) B-Raf proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (RMIL serine/threonine-protein kinase) (c-RMIL) Length = 807 Score = 33.9 bits (76), Expect = 0.40 Identities = 37/152 (24%), Positives = 63/152 (41%), Gaps = 8/152 (5%) Frame = -3 Query: 615 SGHTGYMSPEYAM---DGVFSMKSDIYSFGVMVLEIVTGKKNRGFYDAELDLNLLGYAWT 445 SG +M+PE +S +SD+Y+FG+++ E++TG+ N+ Sbjct: 654 SGSILWMAPEVIRMQDKNPYSFQSDVYAFGIVLYELMTGQLPYS--------NINNRDQI 705 Query: 444 LWKEGRSTELLDEAMMGSSCDHSQVRRCIQVALLCVDMNPRNRPLMSSIVMMLATENATL 265 ++ GR D + + S+C + R + C+ RPL I+ + +L Sbjct: 706 IFMVGRGYLSPDLSKVRSNCPKAMKRLMAE----CLKKKRDERPLFPQILASIELLARSL 761 Query: 264 PE----PNEPGGN-VGKSTSDGELSQTQSELT 184 P+ +EP N G T D L S T Sbjct: 762 PKIHRSASEPSLNRAGFQTEDFSLYACASPKT 793
>SRMS_MOUSE (Q62270) Tyrosine-protein kinase Srms (EC 2.7.10.2) (PTK70)| Length = 496 Score = 33.9 bits (76), Expect = 0.40 Identities = 14/30 (46%), Positives = 22/30 (73%) Frame = -3 Query: 600 YMSPEYAMDGVFSMKSDIYSFGVMVLEIVT 511 + +PE A VFS KSD++SFG+++ E+ T Sbjct: 396 WTAPEAANYRVFSQKSDVWSFGILLYEVFT 425
>RAF1_RAT (P11345) RAF proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (Raf-1) (C-RAF) (cRaf) Length = 648 Score = 33.9 bits (76), Expect = 0.40 Identities = 28/124 (22%), Positives = 54/124 (43%), Gaps = 3/124 (2%) Frame = -3 Query: 615 SGHTGYMSPEYAM---DGVFSMKSDIYSFGVMVLEIVTGKKNRGFYDAELDLNLLGYAWT 445 +G +M+PE + FS +SD+YS+G+++ E++TG+ + + Sbjct: 506 TGSVLWMAPEVIRMQDNNPFSFQSDVYSYGIVLYELMTGELPYSHINNRDQI-------- 557 Query: 444 LWKEGRSTELLDEAMMGSSCDHSQVRRCIQVALLCVDMNPRNRPLMSSIVMMLATENATL 265 ++ GR D + + +C + R + CV RPL I+ + +L Sbjct: 558 IFMVGRGYASPDLSRLYKNCPKAMKR----LVADCVKKVKEERPLFPQILSSIELLQHSL 613 Query: 264 PEPN 253 P+ N Sbjct: 614 PKIN 617
>RAF1_MOUSE (Q99N57) RAF proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (Raf-1) (C-RAF) (cRaf) Length = 648 Score = 33.9 bits (76), Expect = 0.40 Identities = 28/124 (22%), Positives = 53/124 (42%), Gaps = 3/124 (2%) Frame = -3 Query: 615 SGHTGYMSPEYAM---DGVFSMKSDIYSFGVMVLEIVTGKKNRGFYDAELDLNLLGYAWT 445 +G +M+PE D FS +SD+YS+G+++ E++ G+ + + Sbjct: 506 TGSVLWMAPEVIRMQDDNPFSFQSDVYSYGIVLYELMAGELPYAHINNRDQI-------- 557 Query: 444 LWKEGRSTELLDEAMMGSSCDHSQVRRCIQVALLCVDMNPRNRPLMSSIVMMLATENATL 265 ++ GR D + + +C + R + CV RPL I+ + +L Sbjct: 558 IFMVGRGYASPDLSRLYKNCPKAMKR----LVADCVKKVKEERPLFPQILSSIELLQHSL 613 Query: 264 PEPN 253 P+ N Sbjct: 614 PKIN 617
>RAF1_HUMAN (P04049) RAF proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (Raf-1) (C-RAF) (cRaf) Length = 648 Score = 33.9 bits (76), Expect = 0.40 Identities = 28/124 (22%), Positives = 54/124 (43%), Gaps = 3/124 (2%) Frame = -3 Query: 615 SGHTGYMSPEYAM---DGVFSMKSDIYSFGVMVLEIVTGKKNRGFYDAELDLNLLGYAWT 445 +G +M+PE + FS +SD+YS+G+++ E++TG+ + + Sbjct: 506 TGSVLWMAPEVIRMQDNNPFSFQSDVYSYGIVLYELMTGELPYSHINNRDQI-------- 557 Query: 444 LWKEGRSTELLDEAMMGSSCDHSQVRRCIQVALLCVDMNPRNRPLMSSIVMMLATENATL 265 ++ GR D + + +C + R + CV RPL I+ + +L Sbjct: 558 IFMVGRGYASPDLSKLYKNCPKAMKR----LVADCVKKVKEERPLFPQILSSIELLQHSL 613 Query: 264 PEPN 253 P+ N Sbjct: 614 PKIN 617
>SPKA_SYNY3 (Q9FAB3) Serine/threonine-protein kinase A (EC 2.7.11.1)| Length = 521 Score = 33.9 bits (76), Expect = 0.40 Identities = 16/36 (44%), Positives = 21/36 (58%) Frame = -3 Query: 612 GHTGYMSPEYAMDGVFSMKSDIYSFGVMVLEIVTGK 505 G Y SPE +SDIYS GVM+ E++TG+ Sbjct: 190 GTLAYCSPEQMEGKELDSRSDIYSLGVMMYEMLTGE 225
>RMIL_AVII1 (P10533) Serine/threonine-protein kinase transforming protein Rmil| (EC 2.7.11.1) Length = 367 Score = 33.9 bits (76), Expect = 0.40 Identities = 37/152 (24%), Positives = 63/152 (41%), Gaps = 8/152 (5%) Frame = -3 Query: 615 SGHTGYMSPEYAM---DGVFSMKSDIYSFGVMVLEIVTGKKNRGFYDAELDLNLLGYAWT 445 SG +M+PE +S +SD+Y+FG+++ E++TG+ N+ Sbjct: 224 SGSILWMAPEVIRMQDKNPYSFQSDVYAFGIVLYELMTGQLPYS--------NINNRDQI 275 Query: 444 LWKEGRSTELLDEAMMGSSCDHSQVRRCIQVALLCVDMNPRNRPLMSSIVMMLATENATL 265 ++ GR D + + S+C + R + C+ RPL I+ + +L Sbjct: 276 IFMVGRGYLSPDLSKVRSNCPKAMKRLMAE----CLKKKRDERPLFPQILASIELLARSL 331 Query: 264 PE----PNEPGGN-VGKSTSDGELSQTQSELT 184 P+ +EP N G T D L S T Sbjct: 332 PKIHRSASEPSLNRAGFQTEDFSLYACASPKT 363
>PKNB_MYCTU (P0A5S4) Probable serine/threonine-protein kinase pknB (EC| 2.7.11.1) Length = 626 Score = 33.9 bits (76), Expect = 0.40 Identities = 14/36 (38%), Positives = 22/36 (61%) Frame = -3 Query: 612 GHTGYMSPEYAMDGVFSMKSDIYSFGVMVLEIVTGK 505 G Y+SPE A +SD+YS G ++ E++TG+ Sbjct: 178 GTAQYLSPEQARGDSVDARSDVYSLGCVLYEVLTGE 213
>PKNB_MYCBO (P0A5S5) Probable serine/threonine-protein kinase pknB (EC| 2.7.11.1) Length = 626 Score = 33.9 bits (76), Expect = 0.40 Identities = 14/36 (38%), Positives = 22/36 (61%) Frame = -3 Query: 612 GHTGYMSPEYAMDGVFSMKSDIYSFGVMVLEIVTGK 505 G Y+SPE A +SD+YS G ++ E++TG+ Sbjct: 178 GTAQYLSPEQARGDSVDARSDVYSLGCVLYEVLTGE 213
>SRC64_DROME (P00528) Tyrosine-protein kinase Src64B (EC 2.7.10.2) (Dsrc64)| Length = 552 Score = 33.9 bits (76), Expect = 0.40 Identities = 12/30 (40%), Positives = 24/30 (80%) Frame = -3 Query: 600 YMSPEYAMDGVFSMKSDIYSFGVMVLEIVT 511 + +PE + G FS+KSD++S+G++++E+ T Sbjct: 446 WTAPEAIIYGKFSIKSDVWSYGILLMELFT 475
>FGFR4_RAT (Q498D6) Fibroblast growth factor receptor 4 precursor (EC| 2.7.10.1) (FGFR-4) Length = 800 Score = 33.9 bits (76), Expect = 0.40 Identities = 13/30 (43%), Positives = 23/30 (76%) Frame = -3 Query: 600 YMSPEYAMDGVFSMKSDIYSFGVMVLEIVT 511 +M+PE D V++ +SD++SFG+++ EI T Sbjct: 653 WMAPEALFDRVYTHQSDVWSFGILLWEIFT 682
>FGFR4_HUMAN (P22455) Fibroblast growth factor receptor 4 precursor (EC| 2.7.10.1) (FGFR-4) (CD334 antigen) Length = 802 Score = 33.9 bits (76), Expect = 0.40 Identities = 13/30 (43%), Positives = 23/30 (76%) Frame = -3 Query: 600 YMSPEYAMDGVFSMKSDIYSFGVMVLEIVT 511 +M+PE D V++ +SD++SFG+++ EI T Sbjct: 655 WMAPEALFDRVYTHQSDVWSFGILLWEIFT 684
>VGFR2_COTJA (P52583) Vascular endothelial growth factor receptor 2 precursor (EC| 2.7.10.1) (VEGFR-2) (Endothelial kinase receptor EK1) (Quek 1) (Quek1) Length = 1348 Score = 33.9 bits (76), Expect = 0.40 Identities = 13/28 (46%), Positives = 23/28 (82%) Frame = -3 Query: 600 YMSPEYAMDGVFSMKSDIYSFGVMVLEI 517 +M+PE D V++++SD++SFGV++ EI Sbjct: 1064 WMAPETIFDRVYTIQSDVWSFGVLLWEI 1091
>M3K7_HUMAN (O43318) Mitogen-activated protein kinase kinase kinase 7 (EC| 2.7.11.25) (Transforming growth factor-beta-activated kinase 1) (TGF-beta-activated kinase 1) Length = 606 Score = 33.9 bits (76), Expect = 0.40 Identities = 35/160 (21%), Positives = 61/160 (38%), Gaps = 9/160 (5%) Frame = -3 Query: 618 SSGHTGYMSPEYAMDGVFSMKSDIYSFGVMVLEIVTGKKNRGFYDAELDLNLLGYAWTLW 439 + G +M+PE +S K D++S+G+++ E++T +K +D E+ W + Sbjct: 189 NKGSAAWMAPEVFEGSNYSEKCDVFSWGIILWEVITRRKP---FD-EIGGPAFRIMWAVH 244 Query: 438 KEGRSTELLDEAMMGSSCDHSQVRRCIQVALLCVDMNPRNRPLMSSIVMMLATENATLPE 259 R + + + + R C +P RP M IV ++ P Sbjct: 245 NGTRPPLIKN---LPKPIESLMTR--------CWSKDPSQRPSMEEIVKIMTHLMRYFPG 293 Query: 258 PNEP---------GGNVGKSTSDGELSQTQSELTVTVTDT 166 +EP G +TS G S T +DT Sbjct: 294 ADEPLQYPCQYSDEGQSNSATSTGSFMDIASTNTSNKSDT 333
>CSF1R_MOUSE (P09581) Macrophage colony-stimulating factor 1 receptor precursor| (CSF-1-R) (EC 2.7.10.1) (Fms proto-oncogene) (c-fms) Length = 977 Score = 33.9 bits (76), Expect = 0.40 Identities = 33/144 (22%), Positives = 55/144 (38%), Gaps = 7/144 (4%) Frame = -3 Query: 600 YMSPEYAMDGVFSMKSDIYSFGVMVLEIVTGKKNRGFYDAELDLNLLGYAWTLWKEGRST 421 +M+PE D V++++SD++S+G+++ EI L L Y L Sbjct: 819 WMAPESIFDCVYTVQSDVWSYGILLWEI-------------FSLGLNPYPGILVNNKFYK 865 Query: 420 ELLDEAMMGSSCDHSQVRRCIQVALLCVDMNPRNRPLMSSIVMMLATENATLPEPNE--- 250 + D M + + C D+ P RP I +L E A L ++ Sbjct: 866 LVKDGYQMAQPV--FAPKNIYSIMQSCWDLEPTRRPTFQQICFLL-QEQARLERRDQDYA 922 Query: 249 ----PGGNVGKSTSDGELSQTQSE 190 GG+ G + G + SE Sbjct: 923 NLPSSGGSSGSDSGGGSSGGSSSE 946
>JAK3_MOUSE (Q62137) Tyrosine-protein kinase JAK3 (EC 2.7.10.2) (Janus kinase 3)| (JAK-3) Length = 1299 Score = 33.9 bits (76), Expect = 0.40 Identities = 13/30 (43%), Positives = 22/30 (73%) Frame = -3 Query: 600 YMSPEYAMDGVFSMKSDIYSFGVMVLEIVT 511 + +PE D +FS +SD++SFGV++ E+ T Sbjct: 1202 WYAPESLSDNIFSRQSDVWSFGVVLYELFT 1231
>FGFR1_XENLA (P22182) Fibroblast growth factor receptor 1 precursor (EC| 2.7.10.1) (FGFR-1) Length = 812 Score = 33.9 bits (76), Expect = 0.40 Identities = 13/30 (43%), Positives = 23/30 (76%) Frame = -3 Query: 600 YMSPEYAMDGVFSMKSDIYSFGVMVLEIVT 511 +M+PE D +++ +SD++SFGV++ EI T Sbjct: 660 WMAPEALFDRIYTHQSDVWSFGVLLWEIFT 689
>M3K7_MOUSE (Q62073) Mitogen-activated protein kinase kinase kinase 7 (EC| 2.7.11.25) (Transforming growth factor-beta-activated kinase 1) (TGF-beta-activated kinase 1) Length = 579 Score = 33.9 bits (76), Expect = 0.40 Identities = 35/160 (21%), Positives = 61/160 (38%), Gaps = 9/160 (5%) Frame = -3 Query: 618 SSGHTGYMSPEYAMDGVFSMKSDIYSFGVMVLEIVTGKKNRGFYDAELDLNLLGYAWTLW 439 + G +M+PE +S K D++S+G+++ E++T +K +D E+ W + Sbjct: 189 NKGSAAWMAPEVFEGSNYSEKCDVFSWGIILWEVITRRKP---FD-EIGGPAFRIMWAVH 244 Query: 438 KEGRSTELLDEAMMGSSCDHSQVRRCIQVALLCVDMNPRNRPLMSSIVMMLATENATLPE 259 R + + + + R C +P RP M IV ++ P Sbjct: 245 NGTRPPLIKN---LPKPIESLMTR--------CWSKDPSQRPSMEEIVKIMTHLMRYFPG 293 Query: 258 PNEP---------GGNVGKSTSDGELSQTQSELTVTVTDT 166 +EP G +TS G S T +DT Sbjct: 294 ADEPLQYPCQYSDEGQSNSATSTGSFMDIASTNTSNKSDT 333
>LTK_HUMAN (P29376) Leukocyte tyrosine kinase receptor precursor (EC 2.7.10.1)| (Protein tyrosine kinase 1) Length = 864 Score = 33.9 bits (76), Expect = 0.40 Identities = 32/110 (29%), Positives = 50/110 (45%), Gaps = 5/110 (4%) Frame = -3 Query: 600 YMSPEYAMDGVFSMKSDIYSFGVMVLEIVTGKKNRGFYDAELDLNLLGYAWTLWKEGRST 421 +M PE ++G+F+ K+D +SFGV++ EI + LGY + GR+ Sbjct: 689 WMPPEAFLEGIFTSKTDSWSFGVLLWEIFS----------------LGY---MPYPGRTN 729 Query: 420 -ELLDEAMMGSSCDHSQVRRC----IQVALLCVDMNPRNRPLMSSIVMML 286 E+LD + G D R C ++ C P RP +SI+ L Sbjct: 730 QEVLDFVVGGGRMD--PPRGCPGPVYRIMTQCWQHEPELRPSFASILERL 777
>LIMK1_CHICK (Q8QFP8) LIM domain kinase 1 (EC 2.7.11.1) (LIMK-1) (chLIMK1)| Length = 662 Score = 33.5 bits (75), Expect = 0.53 Identities = 28/114 (24%), Positives = 45/114 (39%), Gaps = 3/114 (2%) Frame = -3 Query: 612 GHTGYMSPEYAMDGVFSMKSDIYSFGVMVLEIVTGKKNRGFY---DAELDLNLLGYAWTL 442 G+ +M+PE + K DI+SFG+++ EI+ Y + LN+ G+ Sbjct: 518 GNPYWMAPEMINGRSYDEKVDIFSFGIVLCEIIGRVSADPDYLPRTTDFGLNVRGFL--- 574 Query: 441 WKEGRSTELLDEAMMGSSCDHSQVRRCIQVALLCVDMNPRNRPLMSSIVMMLAT 280 E +C S +A C D++P RP S + L T Sbjct: 575 -----------ERYCPPACPPS----FFPIAACCCDLDPEKRPSFSKLEQWLET 613
>M3K13_HUMAN (O43283) Mitogen-activated protein kinase kinase kinase 13 (EC| 2.7.11.25) (Mixed lineage kinase) (MLK) (Leucine zipper-bearing kinase) Length = 966 Score = 33.5 bits (75), Expect = 0.53 Identities = 15/37 (40%), Positives = 25/37 (67%) Frame = -3 Query: 615 SGHTGYMSPEYAMDGVFSMKSDIYSFGVMVLEIVTGK 505 +G +M+PE + S K DI+SFGV++ E++TG+ Sbjct: 314 AGTVAWMAPEVIRNEPVSEKVDIWSFGVVLWELLTGE 350
>LRRK1_MOUSE (Q3UHC2) Leucine-rich repeat serine/threonine-protein kinase 1 (EC| 2.7.11.1) Length = 2014 Score = 33.5 bits (75), Expect = 0.53 Identities = 28/109 (25%), Positives = 49/109 (44%) Frame = -3 Query: 612 GHTGYMSPEYAMDGVFSMKSDIYSFGVMVLEIVTGKKNRGFYDAELDLNLLGYAWTLWKE 433 G GY +PE V+ K D++S+G+++ E+++G++ L + L L K Sbjct: 1426 GTPGYQAPEIRPRIVYDEKVDMFSYGMVLYELLSGQR------PALGHHQLQIVKKLSKG 1479 Query: 432 GRSTELLDEAMMGSSCDHSQVRRCIQVALLCVDMNPRNRPLMSSIVMML 286 R ++G + Q R + + C D P RPL S+V + Sbjct: 1480 IR-------PVLGQP-EEVQFHRLQALMMECWDTKPEKRPLALSVVSQM 1520
>7LESS_DROVI (P20806) Protein sevenless (EC 2.7.10.1)| Length = 2594 Score = 33.5 bits (75), Expect = 0.53 Identities = 14/30 (46%), Positives = 23/30 (76%) Frame = -3 Query: 600 YMSPEYAMDGVFSMKSDIYSFGVMVLEIVT 511 +M+ E +DG+FS +SD+++FGV+ EI T Sbjct: 2404 WMALESLVDGLFSTQSDVWAFGVLCWEIFT 2433
>PKNA_MYCLE (P54743) Probable serine/threonine-protein kinase pknA (EC| 2.7.11.1) Length = 437 Score = 33.5 bits (75), Expect = 0.53 Identities = 15/37 (40%), Positives = 24/37 (64%) Frame = -3 Query: 612 GHTGYMSPEYAMDGVFSMKSDIYSFGVMVLEIVTGKK 502 G Y++PE A+ + SD+YS GV+ E+V+GK+ Sbjct: 179 GTAQYIAPEQALGHDATPASDVYSLGVIGYEVVSGKR 215
>NIR_PHOLA (Q51879) Ferredoxin--nitrite reductase (EC 1.7.7.1)| Length = 510 Score = 33.5 bits (75), Expect = 0.53 Identities = 18/56 (32%), Positives = 32/56 (57%) Frame = -3 Query: 474 DLNLLGYAWTLWKEGRSTELLDEAMMGSSCDHSQVRRCIQVALLCVDMNPRNRPLM 307 D+ L+G + K+G++TE +D M G H+++ C+Q + C D+ P R L+ Sbjct: 448 DIGLMGTK--VRKDGKATEGVDLYMGGKVGKHAELGTCVQKGIPCDDLKPILRNLL 501
>PMYT1_XENLA (Q91618) Membrane-associated tyrosine- and threonine-specific| cdc2-inhibitory kinase (EC 2.7.11.1) (Myt1 kinase) Length = 548 Score = 33.5 bits (75), Expect = 0.53 Identities = 14/32 (43%), Positives = 23/32 (71%) Frame = -3 Query: 612 GHTGYMSPEYAMDGVFSMKSDIYSFGVMVLEI 517 G YM+PE +DG+FS +D++S G+ +LE+ Sbjct: 263 GDPRYMAPEL-LDGIFSKAADVFSLGMSLLEV 293
>ARAF_RAT (P14056) A-Raf proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) Length = 604 Score = 33.5 bits (75), Expect = 0.53 Identities = 27/126 (21%), Positives = 55/126 (43%) Frame = -3 Query: 567 FSMKSDIYSFGVMVLEIVTGKKNRGFYDAELDLNLLGYAWTLWKEGRSTELLDEAMMGSS 388 +S +SD+Y++GV++ E++TG + + ++ GR D + + S+ Sbjct: 484 YSFQSDVYAYGVVLYELMTGSLPYSHIGSRDQI--------IFMVGRGYLSPDLSKIFSN 535 Query: 387 CDHSQVRRCIQVALLCVDMNPRNRPLMSSIVMMLATENATLPEPNEPGGNVGKSTSDGEL 208 C + R C+ RPL I+ + +LP+ + +S S+ L Sbjct: 536 CPKAMRRLLTD----CLKFQREERPLFPQILATIELLQRSLPK-------IERSASEPSL 584 Query: 207 SQTQSE 190 +TQ++ Sbjct: 585 HRTQAD 590
>ARAF_MOUSE (P04627) A-Raf proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) Length = 604 Score = 33.5 bits (75), Expect = 0.53 Identities = 27/126 (21%), Positives = 55/126 (43%) Frame = -3 Query: 567 FSMKSDIYSFGVMVLEIVTGKKNRGFYDAELDLNLLGYAWTLWKEGRSTELLDEAMMGSS 388 +S +SD+Y++GV++ E++TG + + ++ GR D + + S+ Sbjct: 484 YSFQSDVYAYGVVLYELMTGSLPYSHIGSRDQI--------IFMVGRGYLSPDLSKIFSN 535 Query: 387 CDHSQVRRCIQVALLCVDMNPRNRPLMSSIVMMLATENATLPEPNEPGGNVGKSTSDGEL 208 C + R C+ RPL I+ + +LP+ + +S S+ L Sbjct: 536 CPKAMRRLLTD----CLKFQREERPLFPQILATIELLQRSLPK-------IERSASEPSL 584 Query: 207 SQTQSE 190 +TQ++ Sbjct: 585 HRTQAD 590
>SRMS_HUMAN (Q9H3Y6) Tyrosine-protein kinase Srms (EC 2.7.10.2)| Length = 488 Score = 33.5 bits (75), Expect = 0.53 Identities = 15/30 (50%), Positives = 22/30 (73%) Frame = -3 Query: 600 YMSPEYAMDGVFSMKSDIYSFGVMVLEIVT 511 + +PE A VFS KSD++SFGV++ E+ T Sbjct: 392 WTAPEAANYRVFSQKSDVWSFGVLLHEVFT 421
>IRAK1_HUMAN (P51617) Interleukin-1 receptor-associated kinase 1 (EC 2.7.11.1)| (IRAK-1) Length = 712 Score = 33.5 bits (75), Expect = 0.53 Identities = 14/37 (37%), Positives = 23/37 (62%) Frame = -3 Query: 612 GHTGYMSPEYAMDGVFSMKSDIYSFGVMVLEIVTGKK 502 G Y+ EY G ++ +D +SFGV+VLE + G++ Sbjct: 386 GTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQR 422
>VGFR3_HUMAN (P35916) Vascular endothelial growth factor receptor 3 precursor (EC| 2.7.10.1) (VEGFR-3) (Tyrosine-protein kinase receptor FLT4) Length = 1298 Score = 33.5 bits (75), Expect = 0.53 Identities = 36/141 (25%), Positives = 56/141 (39%), Gaps = 5/141 (3%) Frame = -3 Query: 600 YMSPEYAMDGVFSMKSDIYSFGVMVLEIVTGKKNRGFYDAELDLNLLGYAWTLWKEGRST 421 +M+PE D V++ +SD++SFGV++ EI L Y E Sbjct: 1080 WMAPESIFDKVYTTQSDVWSFGVLLWEI-------------FSLGASPYPGVQINEEFCQ 1126 Query: 420 ELLD-EAMMGSSCDHSQVRRCIQVALLCVDMNPRNRPLMSSIVMMLA--TENATLPEPNE 250 L D M +RR + L C +P+ RP S +V +L + L E E Sbjct: 1127 RLRDGTRMRAPELATPAIRR---IMLNCWSGDPKARPAFSELVEILGDLLQGRGLQEEEE 1183 Query: 249 --PGGNVGKSTSDGELSQTQS 193 +S+ +G SQ + Sbjct: 1184 VCMAPRSSQSSEEGSFSQVST 1204
>VGFR3_RAT (Q91ZT1) Vascular endothelial growth factor receptor 3 precursor (EC| 2.7.10.1) (VEGFR-3) (Tyrosine-protein kinase receptor FLT4) Length = 1363 Score = 33.1 bits (74), Expect = 0.69 Identities = 13/28 (46%), Positives = 22/28 (78%) Frame = -3 Query: 600 YMSPEYAMDGVFSMKSDIYSFGVMVLEI 517 +M+PE D V++ +SD++SFGV++ EI Sbjct: 1080 WMAPESIFDKVYTTQSDVWSFGVLLWEI 1107
>VGFR3_MOUSE (P35917) Vascular endothelial growth factor receptor 3 precursor (EC| 2.7.10.1) (VEGFR-3) (Tyrosine-protein kinase receptor FLT4) Length = 1363 Score = 33.1 bits (74), Expect = 0.69 Identities = 13/28 (46%), Positives = 22/28 (78%) Frame = -3 Query: 600 YMSPEYAMDGVFSMKSDIYSFGVMVLEI 517 +M+PE D V++ +SD++SFGV++ EI Sbjct: 1080 WMAPESIFDKVYTTQSDVWSFGVLLWEI 1107
>STE7_CANAL (P46599) Serine/threonine-protein kinase STE7 homolog (EC 2.7.12.2)| Length = 589 Score = 33.1 bits (74), Expect = 0.69 Identities = 14/35 (40%), Positives = 24/35 (68%) Frame = -3 Query: 612 GHTGYMSPEYAMDGVFSMKSDIYSFGVMVLEIVTG 508 G + YMSPE + +KSD++S G+M++E+ +G Sbjct: 411 GTSMYMSPERIQGLDYGVKSDVWSTGLMLIELASG 445
>ROR2_HUMAN (Q01974) Tyrosine-protein kinase transmembrane receptor ROR2| precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase, receptor-related 2) Length = 943 Score = 33.1 bits (74), Expect = 0.69 Identities = 14/28 (50%), Positives = 22/28 (78%) Frame = -3 Query: 600 YMSPEYAMDGVFSMKSDIYSFGVMVLEI 517 +M+PE M G FS+ SDI+S+GV++ E+ Sbjct: 658 WMAPEAIMYGKFSIDSDIWSYGVVLWEV 685
>PKN2_CLOPE (Q8XJL8) Probable serine/threonine protein kinase CPE1738 (EC| 2.7.11.1) Length = 685 Score = 33.1 bits (74), Expect = 0.69 Identities = 14/35 (40%), Positives = 21/35 (60%) Frame = -3 Query: 612 GHTGYMSPEYAMDGVFSMKSDIYSFGVMVLEIVTG 508 G Y SPE A ++D+YS G+++ E+VTG Sbjct: 171 GSAHYFSPEQAKGTYTDYRTDLYSLGIVLYEMVTG 205
>M3KSL_DROME (Q95UN8) Mitogen-activated protein kinase kinase kinase (EC| 2.7.11.25) (Mixed lineage kinase) (dMLK) (Protein slipper) Length = 1161 Score = 33.1 bits (74), Expect = 0.69 Identities = 13/38 (34%), Positives = 25/38 (65%) Frame = -3 Query: 618 SSGHTGYMSPEYAMDGVFSMKSDIYSFGVMVLEIVTGK 505 ++G +M PE +S SD++S+GV++ E++TG+ Sbjct: 305 AAGTYAWMPPEVISVSTYSKFSDVWSYGVLLWELITGE 342
>RAF_MSV36 (P00532) Serine/threonine-protein kinase transforming protein raf| (EC 2.7.11.1) Length = 323 Score = 33.1 bits (74), Expect = 0.69 Identities = 28/124 (22%), Positives = 55/124 (44%), Gaps = 3/124 (2%) Frame = -3 Query: 615 SGHTGYMSPEYAM---DGVFSMKSDIYSFGVMVLEIVTGKKNRGFYDAELDLNLLGYAWT 445 +G +M+PE D FS +SD+YS+G+++ E++ G+ + + Sbjct: 181 TGSVLWMAPEVIRMQDDNPFSFQSDVYSYGIVLYELMAGELPYAHINNRDQI-------- 232 Query: 444 LWKEGRSTELLDEAMMGSSCDHSQVRRCIQVALLCVDMNPRNRPLMSSIVMMLATENATL 265 ++ GR D + + +C + ++R + CV RPL I+ + +L Sbjct: 233 IFMVGRGYASPDLSRLYKNCPKA-IKRLVAD---CVKKVKEERPLFPQILSSIELLQHSL 288 Query: 264 PEPN 253 P+ N Sbjct: 289 PKIN 292
>NTRK3_SAIBB (Q5IS82) NT-3 growth factor receptor precursor (EC 2.7.10.1)| (Neurotrophic tyrosine kinase receptor type 3) Length = 825 Score = 33.1 bits (74), Expect = 0.69 Identities = 30/115 (26%), Positives = 48/115 (41%), Gaps = 6/115 (5%) Frame = -3 Query: 612 GHT----GYMSPEYAMDGVFSMKSDIYSFGVMVLEIVTGKKNRGFYDAELDLNLLGYAWT 445 GHT +M PE M F+ +SD++SFGV++ EI T Y Sbjct: 714 GHTMLPIRWMPPESIMYRKFTTESDVWSFGVILWEIFT------------------YGKQ 755 Query: 444 LWKEGRSTELLDEAMMGSSCDHSQV--RRCIQVALLCVDMNPRNRPLMSSIVMML 286 W + +TE+++ G + +V + V L C P+ R + I +L Sbjct: 756 PWFQLSNTEVIECITQGRVLERPRVCPKEVYDVMLGCWQREPQQRLNIKEIYKIL 810
>NTRK3_PIG (P24786) NT-3 growth factor receptor precursor (EC 2.7.10.1)| (Neurotrophic tyrosine kinase receptor type 3) (TrkC tyrosine kinase) (GP145-TrkC) (Trk-C) Length = 825 Score = 33.1 bits (74), Expect = 0.69 Identities = 30/115 (26%), Positives = 48/115 (41%), Gaps = 6/115 (5%) Frame = -3 Query: 612 GHT----GYMSPEYAMDGVFSMKSDIYSFGVMVLEIVTGKKNRGFYDAELDLNLLGYAWT 445 GHT +M PE M F+ +SD++SFGV++ EI T Y Sbjct: 714 GHTMLPIRWMPPESIMYRKFTTESDVWSFGVILWEIFT------------------YGKQ 755 Query: 444 LWKEGRSTELLDEAMMGSSCDHSQV--RRCIQVALLCVDMNPRNRPLMSSIVMML 286 W + +TE+++ G + +V + V L C P+ R + I +L Sbjct: 756 PWFQLSNTEVIECITQGRVLERPRVCPKEVYDVMLGCWQREPQQRLNIKEIYKIL 810
>NTRK3_PANTR (Q5IS37) NT-3 growth factor receptor precursor (EC 2.7.10.1)| (Neurotrophic tyrosine kinase receptor type 3) Length = 825 Score = 33.1 bits (74), Expect = 0.69 Identities = 30/115 (26%), Positives = 48/115 (41%), Gaps = 6/115 (5%) Frame = -3 Query: 612 GHT----GYMSPEYAMDGVFSMKSDIYSFGVMVLEIVTGKKNRGFYDAELDLNLLGYAWT 445 GHT +M PE M F+ +SD++SFGV++ EI T Y Sbjct: 714 GHTMLPIRWMPPESIMYRKFTTESDVWSFGVILWEIFT------------------YGKQ 755 Query: 444 LWKEGRSTELLDEAMMGSSCDHSQV--RRCIQVALLCVDMNPRNRPLMSSIVMML 286 W + +TE+++ G + +V + V L C P+ R + I +L Sbjct: 756 PWFQLSNTEVIECITQGRVLERPRVCPKEVYDVMLGCWQREPQQRLNIKEIYKIL 810
>NTRK3_MACFA (Q5IFJ9) NT-3 growth factor receptor precursor (EC 2.7.10.1)| (Neurotrophic tyrosine kinase receptor type 3) Length = 825 Score = 33.1 bits (74), Expect = 0.69 Identities = 30/115 (26%), Positives = 48/115 (41%), Gaps = 6/115 (5%) Frame = -3 Query: 612 GHT----GYMSPEYAMDGVFSMKSDIYSFGVMVLEIVTGKKNRGFYDAELDLNLLGYAWT 445 GHT +M PE M F+ +SD++SFGV++ EI T Y Sbjct: 714 GHTMLPIRWMPPESIMYRKFTTESDVWSFGVILWEIFT------------------YGKQ 755 Query: 444 LWKEGRSTELLDEAMMGSSCDHSQV--RRCIQVALLCVDMNPRNRPLMSSIVMML 286 W + +TE+++ G + +V + V L C P+ R + I +L Sbjct: 756 PWFQLSNTEVIECITQGRVLERPRVCPKEVYDVMLGCWQREPQQRLNIKEIYKIL 810
>NTRK3_HUMAN (Q16288) NT-3 growth factor receptor precursor (EC 2.7.10.1)| (Neurotrophic tyrosine kinase receptor type 3) (TrkC tyrosine kinase) (GP145-TrkC) (Trk-C) Length = 839 Score = 33.1 bits (74), Expect = 0.69 Identities = 30/115 (26%), Positives = 48/115 (41%), Gaps = 6/115 (5%) Frame = -3 Query: 612 GHT----GYMSPEYAMDGVFSMKSDIYSFGVMVLEIVTGKKNRGFYDAELDLNLLGYAWT 445 GHT +M PE M F+ +SD++SFGV++ EI T Y Sbjct: 728 GHTMLPIRWMPPESIMYRKFTTESDVWSFGVILWEIFT------------------YGKQ 769 Query: 444 LWKEGRSTELLDEAMMGSSCDHSQV--RRCIQVALLCVDMNPRNRPLMSSIVMML 286 W + +TE+++ G + +V + V L C P+ R + I +L Sbjct: 770 PWFQLSNTEVIECITQGRVLERPRVCPKEVYDVMLGCWQREPQQRLNIKEIYKIL 824
>IRAK1_MOUSE (Q62406) Interleukin-1 receptor-associated kinase 1 (EC 2.7.11.1)| (IRAK-1) (IRAK) (Pelle-like protein kinase) (mPLK) Length = 710 Score = 33.1 bits (74), Expect = 0.69 Identities = 13/37 (35%), Positives = 23/37 (62%) Frame = -3 Query: 612 GHTGYMSPEYAMDGVFSMKSDIYSFGVMVLEIVTGKK 502 G Y+ EY G ++ +D +SFGV++LE + G++ Sbjct: 386 GTLAYLPEEYIKTGRLAVDTDTFSFGVVILETLAGQR 422
>ROR1_HUMAN (Q01973) Tyrosine-protein kinase transmembrane receptor ROR1| precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase, receptor-related 1) Length = 937 Score = 33.1 bits (74), Expect = 0.69 Identities = 16/28 (57%), Positives = 20/28 (71%) Frame = -3 Query: 600 YMSPEYAMDGVFSMKSDIYSFGVMVLEI 517 +M PE M G FS SDI+SFGV++ EI Sbjct: 658 WMPPEAIMYGKFSSDSDIWSFGVVLWEI 685
>PKNA_MYCTU (P65726) Probable serine/threonine-protein kinase pknA (EC| 2.7.11.1) Length = 431 Score = 33.1 bits (74), Expect = 0.69 Identities = 16/37 (43%), Positives = 23/37 (62%) Frame = -3 Query: 612 GHTGYMSPEYAMDGVFSMKSDIYSFGVMVLEIVTGKK 502 G Y++PE A+ S SD+YS GV+ E V+GK+ Sbjct: 179 GTAQYIAPEQALGHDASPASDVYSLGVVGYEAVSGKR 215
>PKNA_MYCBO (P65727) Probable serine/threonine-protein kinase pknA (EC| 2.7.11.1) Length = 431 Score = 33.1 bits (74), Expect = 0.69 Identities = 16/37 (43%), Positives = 23/37 (62%) Frame = -3 Query: 612 GHTGYMSPEYAMDGVFSMKSDIYSFGVMVLEIVTGKK 502 G Y++PE A+ S SD+YS GV+ E V+GK+ Sbjct: 179 GTAQYIAPEQALGHDASPASDVYSLGVVGYEAVSGKR 215
>PKN3_MYXXA (Q9XBQ0) Serine/threonine-protein kinase pkn3 (EC 2.7.11.1)| Length = 547 Score = 33.1 bits (74), Expect = 0.69 Identities = 14/35 (40%), Positives = 22/35 (62%) Frame = -3 Query: 612 GHTGYMSPEYAMDGVFSMKSDIYSFGVMVLEIVTG 508 G YMSPE A +SD+Y+ GV++ +++TG Sbjct: 188 GTPEYMSPEQARGSQLDHRSDLYAVGVILYQLMTG 222
>MEK2_CAEEL (Q10664) Dual specificity mitogen-activated protein kinase kinase| mek-2 (EC 2.7.12.2) (MAP kinase kinase mek-2) Length = 387 Score = 33.1 bits (74), Expect = 0.69 Identities = 13/36 (36%), Positives = 24/36 (66%) Frame = -3 Query: 612 GHTGYMSPEYAMDGVFSMKSDIYSFGVMVLEIVTGK 505 G YM+PE +++ SDI+SFG+ ++E++ G+ Sbjct: 230 GTRSYMAPERLTGSHYTISSDIWSFGLSLVELLIGR 265
>LRRK2_HUMAN (Q5S007) Leucine-rich repeat serine/threonine-protein kinase 2 (EC| 2.7.11.1) (Dardarin) Length = 2527 Score = 33.1 bits (74), Expect = 0.69 Identities = 14/37 (37%), Positives = 26/37 (70%), Gaps = 1/37 (2%) Frame = -3 Query: 618 SSGHTGYMSPEYAMDGV-FSMKSDIYSFGVMVLEIVT 511 S G G+ +PE A V ++ ++D+YSFG+++ +I+T Sbjct: 2032 SEGTPGFRAPEVARGNVIYNQQADVYSFGLLLYDILT 2068
>NTRK3_RAT (Q03351) NT-3 growth factor receptor precursor (EC 2.7.10.1)| (Neurotrophic tyrosine kinase receptor type 3) (TrkC tyrosine kinase) (GP145-TrkC) (Trk-C) Length = 864 Score = 33.1 bits (74), Expect = 0.69 Identities = 30/115 (26%), Positives = 48/115 (41%), Gaps = 6/115 (5%) Frame = -3 Query: 612 GHT----GYMSPEYAMDGVFSMKSDIYSFGVMVLEIVTGKKNRGFYDAELDLNLLGYAWT 445 GHT +M PE M F+ +SD++SFGV++ EI T Y Sbjct: 753 GHTMLPIRWMPPESIMYRKFTTESDVWSFGVILWEIFT------------------YGKQ 794 Query: 444 LWKEGRSTELLDEAMMGSSCDHSQV--RRCIQVALLCVDMNPRNRPLMSSIVMML 286 W + +TE+++ G + +V + V L C P+ R + I +L Sbjct: 795 PWFQLSNTEVIECITQGRVLERPRVCPKEVYDVMLGCWQREPQQRLNIKEIYKIL 849
>MP2K2_MOUSE (Q63932) Dual specificity mitogen-activated protein kinase kinase 2| (EC 2.7.12.2) (MAP kinase kinase 2) (MAPKK 2) (ERK activator kinase 2) (MAPK/ERK kinase 2) (MEK2) Length = 401 Score = 32.7 bits (73), Expect = 0.90 Identities = 14/36 (38%), Positives = 23/36 (63%) Frame = -3 Query: 612 GHTGYMSPEYAMDGVFSMKSDIYSFGVMVLEIVTGK 505 G YMSPE +S++SDI+S G+ ++E+ G+ Sbjct: 229 GTRSYMSPERLQGTHYSVQSDIWSMGLSLVELAIGR 264
>MP2K1_CRIGR (Q63980) Dual specificity mitogen-activated protein kinase kinase 1| (EC 2.7.12.2) (MAP kinase kinase 1) (MAPKK 1) (ERK activator kinase 1) (MAPK/ERK kinase 1) (MEK1) Length = 393 Score = 32.7 bits (73), Expect = 0.90 Identities = 14/36 (38%), Positives = 23/36 (63%) Frame = -3 Query: 612 GHTGYMSPEYAMDGVFSMKSDIYSFGVMVLEIVTGK 505 G YMSPE +S++SDI+S G+ ++E+ G+ Sbjct: 225 GTRSYMSPERLQGTHYSVQSDIWSMGLSLVEMAVGR 260
>PKNA2_BIFLO (Q8G4G1) Probable serine/threonine-protein kinase pknA2 (EC| 2.7.11.1) Length = 757 Score = 32.7 bits (73), Expect = 0.90 Identities = 13/36 (36%), Positives = 22/36 (61%) Frame = -3 Query: 612 GHTGYMSPEYAMDGVFSMKSDIYSFGVMVLEIVTGK 505 G Y++PE + + + D+YS G+M E++TGK Sbjct: 178 GTAAYLAPEMIENNQATAQGDLYSVGIMAWEMLTGK 213
>LIMK1_XENLA (O42565) LIM domain kinase 1 (EC 2.7.11.1) (LIMK-1) (xLIMK1)| Length = 615 Score = 32.7 bits (73), Expect = 0.90 Identities = 26/109 (23%), Positives = 46/109 (42%) Frame = -3 Query: 612 GHTGYMSPEYAMDGVFSMKSDIYSFGVMVLEIVTGKKNRGFYDAELDLNLLGYAWTLWKE 433 G+ +M+PE + D++SFG+++ EI+ G +A+ D Y Sbjct: 479 GNPYWMAPEMINGRSYDESVDVFSFGIVICEII------GLVNADPD-----YLPRTMDF 527 Query: 432 GRSTELLDEAMMGSSCDHSQVRRCIQVALLCVDMNPRNRPLMSSIVMML 286 G + A + C + A+LC D++P RP S + + L Sbjct: 528 GLNV----RAFLDRFCPPNCPPGFFPSAVLCCDLDPEKRPRFSQLQLWL 572
>NTRK3_CHICK (Q91044) NT-3 growth factor receptor precursor (EC 2.7.10.1)| (Neurotrophic tyrosine kinase receptor type 3) (TrkC tyrosine kinase) (Trk-C) Length = 827 Score = 32.7 bits (73), Expect = 0.90 Identities = 29/115 (25%), Positives = 48/115 (41%), Gaps = 6/115 (5%) Frame = -3 Query: 612 GHT----GYMSPEYAMDGVFSMKSDIYSFGVMVLEIVTGKKNRGFYDAELDLNLLGYAWT 445 GHT +M PE M F+ +SD++SFGV++ EI T Y Sbjct: 716 GHTMLPIRWMPPESIMYRKFTTESDVWSFGVILWEIFT------------------YGKQ 757 Query: 444 LWKEGRSTELLDEAMMGSSCDHSQV--RRCIQVALLCVDMNPRNRPLMSSIVMML 286 W + +TE+++ G + +V + + L C P+ R + I +L Sbjct: 758 PWFQLSNTEVIECITQGRVLERPRVCPKEVYDIMLGCWQREPQQRLNIKEIYKIL 812
>MP2K1_RAT (Q01986) Dual specificity mitogen-activated protein kinase kinase 1| (EC 2.7.12.2) (MAP kinase kinase 1) (MAPKK 1) (ERK activator kinase 1) (MAPK/ERK kinase 1) (MEK1) Length = 392 Score = 32.7 bits (73), Expect = 0.90 Identities = 14/36 (38%), Positives = 23/36 (63%) Frame = -3 Query: 612 GHTGYMSPEYAMDGVFSMKSDIYSFGVMVLEIVTGK 505 G YMSPE +S++SDI+S G+ ++E+ G+ Sbjct: 224 GTRSYMSPERLQGTHYSVQSDIWSMGLSLVEMAVGR 259
>MP2K1_RABIT (P29678) Dual specificity mitogen-activated protein kinase kinase 1| (EC 2.7.12.2) (MAP kinase kinase 1) (MAPKK 1) (ERK activator kinase 1) (MAPK/ERK kinase 1) (MEK1) Length = 392 Score = 32.7 bits (73), Expect = 0.90 Identities = 14/36 (38%), Positives = 23/36 (63%) Frame = -3 Query: 612 GHTGYMSPEYAMDGVFSMKSDIYSFGVMVLEIVTGK 505 G YMSPE +S++SDI+S G+ ++E+ G+ Sbjct: 224 GTRSYMSPERLQGTHYSVQSDIWSMGLSLVEMAVGR 259
>MP2K1_MOUSE (P31938) Dual specificity mitogen-activated protein kinase kinase 1| (EC 2.7.12.2) (MAP kinase kinase 1) (MAPKK 1) (ERK activator kinase 1) (MAPK/ERK kinase 1) (MEK1) Length = 392 Score = 32.7 bits (73), Expect = 0.90 Identities = 14/36 (38%), Positives = 23/36 (63%) Frame = -3 Query: 612 GHTGYMSPEYAMDGVFSMKSDIYSFGVMVLEIVTGK 505 G YMSPE +S++SDI+S G+ ++E+ G+ Sbjct: 224 GTRSYMSPERLQGTHYSVQSDIWSMGLSLVEMAVGR 259
>MP2K1_HUMAN (Q02750) Dual specificity mitogen-activated protein kinase kinase 1| (EC 2.7.12.2) (MAP kinase kinase 1) (MAPKK 1) (ERK activator kinase 1) (MAPK/ERK kinase 1) (MEK1) Length = 392 Score = 32.7 bits (73), Expect = 0.90 Identities = 14/36 (38%), Positives = 23/36 (63%) Frame = -3 Query: 612 GHTGYMSPEYAMDGVFSMKSDIYSFGVMVLEIVTGK 505 G YMSPE +S++SDI+S G+ ++E+ G+ Sbjct: 224 GTRSYMSPERLQGTHYSVQSDIWSMGLSLVEMAVGR 259
>PMYT1_CAEEL (O18209) Membrane-associated tyrosine- and threonine-specific| cdc2-inhibitory kinase (EC 2.7.11.1) (Myt1 kinase) (Lethal protein 37) Length = 677 Score = 32.7 bits (73), Expect = 0.90 Identities = 30/100 (30%), Positives = 49/100 (49%) Frame = -3 Query: 612 GHTGYMSPEYAMDGVFSMKSDIYSFGVMVLEIVTGKKNRGFYDAELDLNLLGYAWTLWKE 433 G + Y++PE ++G + SDI+S G+ +LE T +LD+ G + W + Sbjct: 265 GDSKYLAPE-VLNGRPTKSSDIFSLGMTILEATT----------DLDVPSNGDS---WHQ 310 Query: 432 GRSTELLDEAMMGSSCDHSQVRRCIQVALLCVDMNPRNRP 313 R+ ++ D G S D +R I L +D +PR RP Sbjct: 311 IRNGQIPDRFFAGISTD---LRSLI---ALMLDSDPRIRP 344
>CSF1R_HUMAN (P07333) Macrophage colony-stimulating factor 1 receptor precursor| (CSF-1-R) (EC 2.7.10.1) (Fms proto-oncogene) (c-fms) (CD115 antigen) Length = 972 Score = 32.7 bits (73), Expect = 0.90 Identities = 33/148 (22%), Positives = 56/148 (37%), Gaps = 9/148 (6%) Frame = -3 Query: 600 YMSPEYAMDGVFSMKSDIYSFGVMVLEIVTGKKNRGFYDAELDLNLLGYAWTLWKEGRST 421 +M+PE D V++++SD++S+G+++ EI L L Y L Sbjct: 821 WMAPESIFDCVYTVQSDVWSYGILLWEI-------------FSLGLNPYPGILVNSKFYK 867 Query: 420 ELLDEAMMGSSCDHSQVRRCIQVALLCVDMNPRNRPLMSSIVMML---------ATENAT 268 + D M + + C + P +RP I L + Sbjct: 868 LVKDGYQMAQPA--FAPKNIYSIMQACWALEPTHRPTFQQICSFLQEQAQEDRRERDYTN 925 Query: 267 LPEPNEPGGNVGKSTSDGELSQTQSELT 184 LP + GG+ G S+S+ E + LT Sbjct: 926 LPSSSRSGGS-GSSSSELEEESSSEHLT 952
>PK1_STRTO (Q9KIG4) Serine/threonine-protein kinase PK-1 (EC 2.7.11.1)| (stoPK-1) Length = 641 Score = 32.7 bits (73), Expect = 0.90 Identities = 12/37 (32%), Positives = 23/37 (62%) Frame = -3 Query: 612 GHTGYMSPEYAMDGVFSMKSDIYSFGVMVLEIVTGKK 502 G Y++PE G + D+Y+ G+++ E++TG+K Sbjct: 178 GTVSYLAPEQIEHGTADPRVDVYACGILLYEMLTGEK 214
>MP2K2_RAT (P36506) Dual specificity mitogen-activated protein kinase kinase 2| (EC 2.7.12.2) (MAP kinase kinase 2) (MAPKK 2) (ERK activator kinase 2) (MAPK/ERK kinase 2) (MEK2) Length = 400 Score = 32.7 bits (73), Expect = 0.90 Identities = 14/36 (38%), Positives = 23/36 (63%) Frame = -3 Query: 612 GHTGYMSPEYAMDGVFSMKSDIYSFGVMVLEIVTGK 505 G YMSPE +S++SDI+S G+ ++E+ G+ Sbjct: 229 GTRSYMSPERLQGTHYSVQSDIWSMGLSLVELAIGR 264
>KYK1_DICDI (P18160) Non-receptor tyrosine kinase spore lysis A (EC 2.7.10.2)| (Tyrosine-protein kinase 1) Length = 1584 Score = 32.7 bits (73), Expect = 0.90 Identities = 15/37 (40%), Positives = 24/37 (64%) Frame = -3 Query: 621 KSSGHTGYMSPEYAMDGVFSMKSDIYSFGVMVLEIVT 511 +S G YM+PE S KSD+YS+G+++ E++T Sbjct: 1464 QSVGCIPYMAPEVFKGDSNSEKSDVYSYGMVLFELLT 1500
>VGFR2_BRARE (Q8AXB3) Vascular endothelial growth factor receptor 2 precursor (EC| 2.7.10.1) (VEGFR-2) (Receptor tyrosine kinase flk-1) Length = 1302 Score = 32.7 bits (73), Expect = 0.90 Identities = 12/28 (42%), Positives = 22/28 (78%) Frame = -3 Query: 600 YMSPEYAMDGVFSMKSDIYSFGVMVLEI 517 +M+PE D +++ +SD++SFGV++ EI Sbjct: 1046 WMAPEAIFDKIYTTQSDVWSFGVLMWEI 1073 Database: uniprot_sprot.fasta Posted date: May 25, 2006 5:36 PM Number of letters in database: 80,573,946 Number of sequences in database: 219,361 Lambda K H 0.318 0.135 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 91,841,728 Number of Sequences: 219361 Number of extensions: 1878312 Number of successful extensions: 5558 Number of sequences better than 10.0: 448 Number of HSP's better than 10.0 without gapping: 5275 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 5515 length of database: 80,573,946 effective HSP length: 107 effective length of database: 57,102,319 effective search space used: 5767334219 frameshift window, decay const: 50, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
