ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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| Clone Name | rbasd20k05 |
|---|---|
| Clone Library Name | barley_pub |
>ALDR_HORVU (P23901) Aldose reductase (EC 1.1.1.21) (AR) (Aldehyde reductase)| Length = 320 Score = 93.6 bits (231), Expect = 3e-19 Identities = 49/140 (35%), Positives = 79/140 (56%), Gaps = 1/140 (0%) Frame = -1 Query: 541 KLRAFCRTNXVHFSAYAPLGRM-KVVADNPVVTSIAESLGRTPAQVALRWGIQQGQSVLP 365 K+ C+ + +H +AY+PLG K +A +PVV +A L +TP QV ++W +Q+G SV+P Sbjct: 199 KIFEACKKHGIHVTAYSPLGSSEKNLAHDPVVEKVANKLNKTPGQVLIKWALQRGTSVIP 258 Query: 364 KSANESRLKENIDLFGWSIPQELCAKFSEIEQVQSPFSVISVSAENERVLRGEQVKRIRN 185 KS+ + R+KENI +FGW IP+E F V+ + +RVL GE++ Sbjct: 259 KSSKDERIKENIQVFGWEIPEE-------------DFKVLCSIKDEKRVLTGEEL----- 300 Query: 184 DSLVHPRSIYKTMDELWDGE 125 + Y++ ++WD E Sbjct: 301 -FVNKTHGPYRSAADVWDHE 319
>NADO1_ORYSA (Q7G764) Probable NAD(P)H-dependent oxidoreductase 1 (EC 1.1.1.-)| Length = 321 Score = 79.7 bits (195), Expect = 5e-15 Identities = 45/145 (31%), Positives = 70/145 (48%), Gaps = 6/145 (4%) Frame = -1 Query: 538 LRAFCRTNXVHFSAYAPLGRM------KVVADNPVVTSIAESLGRTPAQVALRWGIQQGQ 377 LR CR V Y+PLG V D+ V+ IA + G+T AQ+ LRW +QG Sbjct: 199 LREVCRREGVQLCGYSPLGAKGTPWGSAAVMDSGVLQEIAGAKGKTLAQICLRWLYEQGD 258 Query: 376 SVLPKSANESRLKENIDLFGWSIPQELCAKFSEIEQVQSPFSVISVSAENERVLRGEQVK 197 +L K+ NE R+KEN+D+F W + E E ER+ + Q++ Sbjct: 259 VLLVKTYNEKRMKENLDIFNWELTDE----------------------ERERISQLPQLR 296 Query: 196 RIRNDSLVHPRSIYKTMDELWDGEI 122 + + YK++++LWDG++ Sbjct: 297 GLPGLEFISDHGPYKSVEDLWDGDV 321
>NADO2_ORYSA (Q7G765) Probable NAD(P)H-dependent oxidoreductase 2 (EC 1.-.-.-)| Length = 322 Score = 78.6 bits (192), Expect = 1e-14 Identities = 49/143 (34%), Positives = 71/143 (49%), Gaps = 6/143 (4%) Frame = -1 Query: 538 LRAFCRTNXVHFSAYAPLGRM------KVVADNPVVTSIAESLGRTPAQVALRWGIQQGQ 377 LR CR V Y+PLG V D+ V+ IA++ G+T AQ+ LRW +QG Sbjct: 201 LREVCRREGVQLCGYSPLGAKGTPWGSAAVMDSGVLHDIAQTKGKTLAQICLRWMYEQGD 260 Query: 376 SVLPKSANESRLKENIDLFGWSIPQELCAKFSEIEQVQSPFSVISVSAENERVLRGEQVK 197 +L K+ NE+R+KEN+D+F W + +E K S++ Q +R L G Q Sbjct: 261 VLLVKTYNENRMKENLDIFDWELTEEERDKISKLPQ--------------QRGLTGMQ-- 304 Query: 196 RIRNDSLVHPRSIYKTMDELWDG 128 V YK +++LWDG Sbjct: 305 ------FVCDNGPYKCVEDLWDG 321
>6DCS_SOYBN (P26690) NAD(P)H dependent 6'-deoxychalcone synthase (EC 2.3.1.170)| Length = 315 Score = 70.9 bits (172), Expect = 2e-12 Identities = 35/96 (36%), Positives = 61/96 (63%), Gaps = 5/96 (5%) Frame = -1 Query: 541 KLRAFCRTNXVHFSAYAPLGR-----MKVVADNPVVTSIAESLGRTPAQVALRWGIQQGQ 377 KLR FC+ N + +A++PL + V +N V+ IAE+ G++ AQV+LRW +QG Sbjct: 200 KLREFCKENGIIVTAFSPLRKGASRGPNEVMENDVLKEIAEAHGKSIAQVSLRWLYEQGV 259 Query: 376 SVLPKSANESRLKENIDLFGWSIPQELCAKFSEIEQ 269 + +PKS ++ R+ +N+ +F W++ ++ K S+I Q Sbjct: 260 TFVPKSYDKERMNQNLHIFDWALTEQDHHKISQISQ 295
>XYL1_ASPNG (Q9P8R5) NAD(P)H-dependent D-xylose reductase (EC 1.1.1.-) (XR)| Length = 319 Score = 70.5 bits (171), Expect = 3e-12 Identities = 36/89 (40%), Positives = 54/89 (60%), Gaps = 10/89 (11%) Frame = -1 Query: 505 FSAYAPLGRMKVVADNPV----------VTSIAESLGRTPAQVALRWGIQQGQSVLPKSA 356 +S++ PL +++ N V V SIAE GRTPAQV LRW Q+G +V+PKS Sbjct: 214 YSSFGPLSFLELSVQNAVDSPPLFEHQLVKSIAEKHGRTPAQVLLRWATQRGIAVIPKSN 273 Query: 355 NESRLKENIDLFGWSIPQELCAKFSEIEQ 269 N RLK+N+D+ GW++ +E S +++ Sbjct: 274 NPQRLKQNLDVTGWNLEEEEIKAISGLDR 302
>P100_LEIMA (P22045) Probable reductase (EC 1.1.-.-)| Length = 284 Score = 68.9 bits (167), Expect = 8e-12 Identities = 32/82 (39%), Positives = 52/82 (63%) Frame = -1 Query: 544 AKLRAFCRTNXVHFSAYAPLGRMKVVADNPVVTSIAESLGRTPAQVALRWGIQQGQSVLP 365 A LRAFC + A++PLG+ K+++ NP++++I +T AQV LRW IQ+ +P Sbjct: 181 ADLRAFCDAKQIKVEAWSPLGQGKLLS-NPILSAIGAKYNKTAAQVILRWNIQKNLITIP 239 Query: 364 KSANESRLKENIDLFGWSIPQE 299 KS + R++EN D+F + + E Sbjct: 240 KSVHRERIEENADIFDFELGAE 261
>DHB5_MOUSE (P70694) Estradiol 17 beta-dehydrogenase 5 (EC 1.1.1.-)| (17-beta-HSD 5) Length = 323 Score = 65.5 bits (158), Expect = 9e-11 Identities = 36/91 (39%), Positives = 54/91 (59%), Gaps = 10/91 (10%) Frame = -1 Query: 541 KLRAFCRTNXVHFSAYAPLGRMK----------VVADNPVVTSIAESLGRTPAQVALRWG 392 KL FCR+ + AY+ LG + V+ DNPV+ S+A+ RTPA +ALR+ Sbjct: 201 KLLDFCRSKDIVLVAYSALGSHREKQWVDQSSPVLLDNPVLGSMAKKYNRTPALIALRYQ 260 Query: 391 IQQGQSVLPKSANESRLKENIDLFGWSIPQE 299 +Q+G VL KS +E R+KEN+ +F + + E Sbjct: 261 LQRGVVVLAKSFSEKRIKENMQVFEFQLTSE 291
>AK1A1_MOUSE (Q9JII6) Alcohol dehydrogenase [NADP+] (EC 1.1.1.2) (Aldehyde| reductase) (Aldo-keto reductase family 1 member A1) Length = 324 Score = 63.9 bits (154), Expect = 3e-10 Identities = 34/92 (36%), Positives = 54/92 (58%), Gaps = 10/92 (10%) Frame = -1 Query: 541 KLRAFCRTNXVHFSAYAPLGRMK---------VVADNPVVTSIAESLGRTPAQVALRWGI 389 +L A C + +AY+PLG V+ + PVV ++AE GR+PAQ+ LRW + Sbjct: 194 ELIAHCHARGLEVTAYSPLGSSDRAWRHPDEPVLLEEPVVLALAEKHGRSPAQILLRWQV 253 Query: 388 QQGQSVLPKSANESRLKENIDLFGWSI-PQEL 296 Q+ +PKS N SR+ +NI +F ++ P+E+ Sbjct: 254 QRKVICIPKSINPSRILQNIQVFDFTFSPEEM 285
>DKGB_CORSS (P15339) 2,5-diketo-D-gluconic acid reductase B (EC 1.1.1.274)| (2,5-DKG reductase B) (2,5-DKGR B) (25DKGR-B) (AKR5D) Length = 276 Score = 62.8 bits (151), Expect = 6e-10 Identities = 31/92 (33%), Positives = 52/92 (56%) Frame = -1 Query: 544 AKLRAFCRTNXVHFSAYAPLGRMKVVADNPVVTSIAESLGRTPAQVALRWGIQQGQSVLP 365 A LRAF + + +++PL R + ++ +A G TP QV LRW +Q G + +P Sbjct: 171 AALRAFHDEHGIRTESWSPLARRSELLTEQLLQELAVVYGVTPTQVVLRWHVQLGSTPIP 230 Query: 364 KSANESRLKENIDLFGWSIPQELCAKFSEIEQ 269 KSA+ R +EN D+FG+++ + S +E+ Sbjct: 231 KSADPDRQRENADVFGFALTADQVDAISGLER 262
>AK1A1_HUMAN (P14550) Alcohol dehydrogenase [NADP+] (EC 1.1.1.2) (Aldehyde| reductase) (Aldo-keto reductase family 1 member A1) Length = 324 Score = 62.4 bits (150), Expect = 8e-10 Identities = 33/92 (35%), Positives = 54/92 (58%), Gaps = 10/92 (10%) Frame = -1 Query: 541 KLRAFCRTNXVHFSAYAPLGRMK---------VVADNPVVTSIAESLGRTPAQVALRWGI 389 +L A C+ + +AY+PLG V+ + PVV ++AE GR+PAQ+ LRW + Sbjct: 194 ELIAHCQARGLEVTAYSPLGSSDRAWRDPDEPVLLEEPVVLALAEKYGRSPAQILLRWQV 253 Query: 388 QQGQSVLPKSANESRLKENIDLFGWSI-PQEL 296 Q+ +PKS SR+ +NI +F ++ P+E+ Sbjct: 254 QRKVICIPKSITPSRILQNIKVFDFTFSPEEM 285
>AK1A1_RAT (P51635) Alcohol dehydrogenase [NADP+] (EC 1.1.1.2) (Aldehyde| reductase) (Aldo-keto reductase family 1 member A1) (3-DG-reducing enzyme) Length = 324 Score = 62.0 bits (149), Expect = 1e-09 Identities = 33/92 (35%), Positives = 54/92 (58%), Gaps = 10/92 (10%) Frame = -1 Query: 541 KLRAFCRTNXVHFSAYAPLGRMK---------VVADNPVVTSIAESLGRTPAQVALRWGI 389 +L A C+ + +AY+PLG V+ + PVV ++AE GR+PAQ+ LRW + Sbjct: 194 ELIAHCQARGLEVTAYSPLGSSDRAWRHPDEPVLLEEPVVLALAEKHGRSPAQILLRWQV 253 Query: 388 QQGQSVLPKSANESRLKENIDLFGWSI-PQEL 296 Q+ +PKS SR+ +NI +F ++ P+E+ Sbjct: 254 QRKVICIPKSITPSRILQNIQVFDFTFSPEEM 285
>DDBX_BOVIN (P52898) Dihydrodiol dehydrogenase 3 (EC 1.-.-.-) (Prostaglandin F| synthase) Length = 323 Score = 61.6 bits (148), Expect = 1e-09 Identities = 34/92 (36%), Positives = 56/92 (60%), Gaps = 10/92 (10%) Frame = -1 Query: 544 AKLRAFCRTNXVHFSAYAPLGRMKV----------VADNPVVTSIAESLGRTPAQVALRW 395 +KL FC+++ + AY LG ++ + ++PV+++IA+ +TPA VALR+ Sbjct: 200 SKLLDFCKSHDIVLVAYGALGSQRLKEWVNPNLPFLLEDPVLSAIAKKHRQTPALVALRY 259 Query: 394 GIQQGQSVLPKSANESRLKENIDLFGWSIPQE 299 IQ+G VL KS N+ R+KENI +F + + E Sbjct: 260 QIQRGVVVLAKSYNKKRIKENIQVFDFELTPE 291
>AK1A1_PIG (P50578) Alcohol dehydrogenase [NADP+] (EC 1.1.1.2) (Aldehyde| reductase) (Aldo-keto reductase family 1 member A1) Length = 324 Score = 61.6 bits (148), Expect = 1e-09 Identities = 36/119 (30%), Positives = 62/119 (52%), Gaps = 9/119 (7%) Frame = -1 Query: 541 KLRAFCRTNXVHFSAYAPLGRMK---------VVADNPVVTSIAESLGRTPAQVALRWGI 389 +L A C+ + +AY+PLG V+ + PVV ++AE R+PAQ+ LRW + Sbjct: 194 ELIAHCQARGLEVTAYSPLGSSDRAWRDPNEPVLLEEPVVQALAEKYNRSPAQILLRWQV 253 Query: 388 QQGQSVLPKSANESRLKENIDLFGWSIPQELCAKFSEIEQVQSPFSVISVSAENERVLR 212 Q+ +PKS SR+ +NI +F ++ E + + + F V ++ + +RV R Sbjct: 254 QRKVICIPKSVTPSRIPQNIQVFDFTFSPEEMKQLDALNK-NLRFIVPMLTVDGKRVPR 311
>DKGA_ECOLI (Q46857) 2,5-diketo-D-gluconic acid reductase A (EC 1.1.1.274)| (2,5-DKG reductase A) (2,5-DKGR A) (25DKGR-A) (AKR5C) Length = 275 Score = 61.6 bits (148), Expect = 1e-09 Identities = 28/92 (30%), Positives = 56/92 (60%), Gaps = 1/92 (1%) Frame = -1 Query: 541 KLRAFCRTNXVHFSAYAPLGRM-KVVADNPVVTSIAESLGRTPAQVALRWGIQQGQSVLP 365 +L A+ T+ + +++PL + K V D V+ +A+ G+TPAQ+ +RW + G V+P Sbjct: 171 QLHAWNATHKIQTESWSPLAQGGKGVFDQKVIRDLADKYGKTPAQIVIRWHLDSGLVVIP 230 Query: 364 KSANESRLKENIDLFGWSIPQELCAKFSEIEQ 269 KS SR+ EN D++ + + ++ + ++++Q Sbjct: 231 KSVTPSRIAENFDVWDFRLDKDELGEIAKLDQ 262
>DKGA_ECO57 (Q8XBT6) 2,5-diketo-D-gluconic acid reductase A (EC 1.1.1.274)| (2,5-DKG reductase A) (2,5-DKGR A) (25DKGR-A) (AKR5C) Length = 275 Score = 61.6 bits (148), Expect = 1e-09 Identities = 28/92 (30%), Positives = 56/92 (60%), Gaps = 1/92 (1%) Frame = -1 Query: 541 KLRAFCRTNXVHFSAYAPLGRM-KVVADNPVVTSIAESLGRTPAQVALRWGIQQGQSVLP 365 +L A+ T+ + +++PL + K V D V+ +A+ G+TPAQ+ +RW + G V+P Sbjct: 171 QLHAWNATHKIQTESWSPLAQGGKGVFDQKVIRDLADKYGKTPAQIVIRWHLDSGLVVIP 230 Query: 364 KSANESRLKENIDLFGWSIPQELCAKFSEIEQ 269 KS SR+ EN D++ + + ++ + ++++Q Sbjct: 231 KSVTPSRIAENFDVWDFRLDKDELGEIAKLDQ 262
>PGFS2_BOVIN (P52897) Prostaglandin-F synthase 2 (EC 1.1.1.188) (PGF synthase 2)| (PGF 2) (Prostaglandin-D2 11 reductase 2) (PGFSII) Length = 323 Score = 61.2 bits (147), Expect = 2e-09 Identities = 34/92 (36%), Positives = 55/92 (59%), Gaps = 10/92 (10%) Frame = -1 Query: 544 AKLRAFCRTNXVHFSAYAPLGRM----------KVVADNPVVTSIAESLGRTPAQVALRW 395 +KL FC+++ + AYA LG V+ ++PV+ +IA+ +TPA VALR+ Sbjct: 200 SKLLEFCKSHDIVLVAYAALGAQLLSEWVNSNNPVLLEDPVLCAIAKKHKQTPALVALRY 259 Query: 394 GIQQGQSVLPKSANESRLKENIDLFGWSIPQE 299 +Q+G VL KS N+ R+KEN+ +F + + E Sbjct: 260 QVQRGVVVLAKSFNKKRIKENMQVFDFELTPE 291
>PGFS1_BOVIN (P05980) Prostaglandin-F synthase 1 (EC 1.1.1.188) (PGF synthase 1)| (PGF 1) (Prostaglandin-D2 11 reductase 1) (PGFSI) Length = 323 Score = 61.2 bits (147), Expect = 2e-09 Identities = 34/92 (36%), Positives = 55/92 (59%), Gaps = 10/92 (10%) Frame = -1 Query: 544 AKLRAFCRTNXVHFSAYAPLGRM----------KVVADNPVVTSIAESLGRTPAQVALRW 395 +KL FC+++ + AYA LG V+ ++PV+ +IA+ +TPA VALR+ Sbjct: 200 SKLLEFCKSHDIVLVAYAALGAQLLSEWVNSNNPVLLEDPVLCAIAKKHKQTPALVALRY 259 Query: 394 GIQQGQSVLPKSANESRLKENIDLFGWSIPQE 299 +Q+G VL KS N+ R+KEN+ +F + + E Sbjct: 260 QVQRGVVVLAKSFNKKRIKENMQVFDFELTPE 291
>AK1C3_PONPY (Q5R7C9) Aldo-keto reductase family 1 member C3 homolog (EC| 1.-.-.-) (Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase) (EC 1.3.1.20) (3-alpha-hydroxysteroid dehydrogenase type 2) (EC 1.1.1.213) (3-alpha-HSD type 2) (Prostaglandin F synthase) Length = 323 Score = 61.2 bits (147), Expect = 2e-09 Identities = 32/92 (34%), Positives = 55/92 (59%), Gaps = 10/92 (10%) Frame = -1 Query: 544 AKLRAFCRTNXVHFSAYAPLGRMK----------VVADNPVVTSIAESLGRTPAQVALRW 395 +KL FC++ + AY+ LG + V+ ++PV+ ++A+ RTPA +ALR+ Sbjct: 200 SKLLDFCKSKDIVLVAYSALGSQRDKRWVDPNSPVLLEDPVLCALAKKHKRTPALIALRY 259 Query: 394 GIQQGQSVLPKSANESRLKENIDLFGWSIPQE 299 +Q+G VL KS NE R++EN+ +F + + E Sbjct: 260 QLQRGVVVLAKSYNEQRIRENVQVFEFQLTAE 291
>AKC1H_RAT (P51652) Aldo-keto reductase family 1 member C18 (EC 1.1.-.-)| (20-alpha-hydroxysteroid dehydrogenase) (EC 1.1.1.149) (20-alpha-HSD) (HSD1) Length = 323 Score = 60.8 bits (146), Expect = 2e-09 Identities = 30/92 (32%), Positives = 54/92 (58%), Gaps = 10/92 (10%) Frame = -1 Query: 544 AKLRAFCRTNXVHFSAYAPLGRMK----------VVADNPVVTSIAESLGRTPAQVALRW 395 +KL A+C+ N + AY LG + V+ D+P++ ++A+ RTPA +ALR+ Sbjct: 200 SKLLAYCKMNDIVLVAYGALGTQRYKYCINEDTPVLLDDPILCTMAKKYKRTPALIALRY 259 Query: 394 GIQQGQSVLPKSANESRLKENIDLFGWSIPQE 299 +++G L KS NE R++EN+ +F + + + Sbjct: 260 QLERGIVTLVKSFNEERIRENLQVFDFQLASD 291
>PE2R_RABIT (P80508) Prostaglandin-E(2) 9-reductase (EC 1.1.1.189)| (20-alpha-hydroxysteroid dehydrogenase) (EC 1.1.1.149) (20-alpha-HSD) Length = 323 Score = 60.5 bits (145), Expect = 3e-09 Identities = 32/91 (35%), Positives = 54/91 (59%), Gaps = 10/91 (10%) Frame = -1 Query: 541 KLRAFCRTNXVHFSAYAPLGRMK----------VVADNPVVTSIAESLGRTPAQVALRWG 392 KL FC++ + AY+ LG + V+ ++P++ ++A+ +TPA +ALR+ Sbjct: 201 KLLEFCKSKGIVLVAYSALGSHREPEWVDQSAPVLLEDPLIGALAKKHQQTPALIALRYQ 260 Query: 391 IQQGQSVLPKSANESRLKENIDLFGWSIPQE 299 +Q+G VL KS E R+KENI +F + +P E Sbjct: 261 LQRGIVVLAKSFTEKRIKENIQVFEFQLPSE 291
>AKC1H_MOUSE (Q8K023) Aldo-keto reductase family 1 member C18 (EC 1.1.-.-)| (20-alpha-hydroxysteroid dehydrogenase) (EC 1.1.1.149) (20-alpha-HSD) Length = 323 Score = 60.5 bits (145), Expect = 3e-09 Identities = 31/92 (33%), Positives = 53/92 (57%), Gaps = 10/92 (10%) Frame = -1 Query: 544 AKLRAFCRTNXVHFSAYAPLGRMK----------VVADNPVVTSIAESLGRTPAQVALRW 395 +KL A+C+ N + AY LG + V+ D+PV+ ++A+ RTPA +ALR+ Sbjct: 200 SKLLAYCKMNDIVLVAYGALGTQRYKYCINEDTPVLLDDPVLCAMAKKYKRTPALIALRY 259 Query: 394 GIQQGQSVLPKSANESRLKENIDLFGWSIPQE 299 + +G L KS NE R++EN+ +F + + + Sbjct: 260 QLDRGIVALAKSFNEERIRENMQVFDFQLASD 291
>AK1C4_HUMAN (P17516) Aldo-keto reductase family 1 member C4 (EC 1.1.1.-)| (Chlordecone reductase) (EC 1.1.1.225) (CDR) (3-alpha-hydroxysteroid dehydrogenase type I) (EC 1.1.1.50) (3-alpha-HSD1) (Dihydrodiol dehydrogenase 4) (DD4) (HAKRA) Length = 323 Score = 60.1 bits (144), Expect = 4e-09 Identities = 32/92 (34%), Positives = 55/92 (59%), Gaps = 10/92 (10%) Frame = -1 Query: 544 AKLRAFCRTNXVHFSAYAPLGRMK----------VVADNPVVTSIAESLGRTPAQVALRW 395 +KL FC++ + A++ LG + V+ ++PV+ ++A+ RTPA +ALR+ Sbjct: 200 SKLLDFCKSKDIVLVAHSALGTQRHKLWVDPNSPVLLEDPVLCALAKKHKRTPALIALRY 259 Query: 394 GIQQGQSVLPKSANESRLKENIDLFGWSIPQE 299 +Q+G VL KS NE R++ENI +F + + E Sbjct: 260 QLQRGVVVLAKSYNEQRIRENIQVFEFQLTSE 291
>AK1C3_HUMAN (P42330) Aldo-keto reductase family 1 member C3 (EC 1.-.-.-)| (Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase) (EC 1.3.1.20) (3-alpha-hydroxysteroid dehydrogenase type 2) (EC 1.1.1.213) (3-alpha-HSD type 2) (3-alpha-HSD type II, brain) (Prost Length = 323 Score = 60.1 bits (144), Expect = 4e-09 Identities = 31/92 (33%), Positives = 55/92 (59%), Gaps = 10/92 (10%) Frame = -1 Query: 544 AKLRAFCRTNXVHFSAYAPLGRMK----------VVADNPVVTSIAESLGRTPAQVALRW 395 +KL FC++ + AY+ LG + V+ ++PV+ ++A+ RTPA +ALR+ Sbjct: 200 SKLLDFCKSKDIVLVAYSALGSQRDKRWVDPNSPVLLEDPVLCALAKKHKRTPALIALRY 259 Query: 394 GIQQGQSVLPKSANESRLKENIDLFGWSIPQE 299 +Q+G VL KS NE R+++N+ +F + + E Sbjct: 260 QLQRGVVVLAKSYNEQRIRQNVQVFEFQLTAE 291
>AK1C2_HUMAN (P52895) Aldo-keto reductase family 1 member C2 (EC 1.-.-.-)| (Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase) (EC 1.3.1.20) (Type III 3-alpha-hydroxysteroid dehydrogenase) (EC 1.1.1.213) (3-alpha-HSD3) (Chlordecone reductase homolog HAKRD) ( Length = 323 Score = 59.3 bits (142), Expect = 7e-09 Identities = 31/91 (34%), Positives = 54/91 (59%), Gaps = 10/91 (10%) Frame = -1 Query: 541 KLRAFCRTNXVHFSAYAPLGRMK----------VVADNPVVTSIAESLGRTPAQVALRWG 392 KL FC++ + AY+ LG + V+ ++PV+ ++A+ RTPA +ALR+ Sbjct: 201 KLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQ 260 Query: 391 IQQGQSVLPKSANESRLKENIDLFGWSIPQE 299 +Q+G VL KS NE R+++N+ +F + + E Sbjct: 261 LQRGVVVLAKSYNEQRIRQNVQVFEFQLTSE 291
>AK1C1_MACFU (Q95JH6) Aldo-keto reductase family 1 member C1 homolog (EC| 1.-.-.-) (20-alpha-hydroxysteroid dehydrogenase) (EC 1.1.1.149) (20-alpha-HSD) (Dihydrodiol dehydrogenase 1) (DD-1) (DD1) Length = 323 Score = 59.3 bits (142), Expect = 7e-09 Identities = 32/91 (35%), Positives = 54/91 (59%), Gaps = 10/91 (10%) Frame = -1 Query: 541 KLRAFCRTNXVHFSAYAPLGRMK----------VVADNPVVTSIAESLGRTPAQVALRWG 392 KL FC++ + AY+ LG + V+ ++PV+ ++A+ RTPA +ALR+ Sbjct: 201 KLLDFCKSKDIVLVAYSALGSHREKPWVDQNSPVLLEDPVLCALAKKHKRTPALIALRYQ 260 Query: 391 IQQGQSVLPKSANESRLKENIDLFGWSIPQE 299 +Q+G VL KS NE R++EN+ +F + + E Sbjct: 261 LQRGVVVLAKSYNEQRIRENMKVFEFQLTSE 291
>AK1C1_HUMAN (Q04828) Aldo-keto reductase family 1 member C1 (EC 1.1.1.-)| (20-alpha-hydroxysteroid dehydrogenase) (EC 1.1.1.149) (20-alpha-HSD) (Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase) (EC 1.3.1.20) (High-affinity hepatic bile acid-binding protei Length = 323 Score = 59.3 bits (142), Expect = 7e-09 Identities = 31/91 (34%), Positives = 54/91 (59%), Gaps = 10/91 (10%) Frame = -1 Query: 541 KLRAFCRTNXVHFSAYAPLGRMK----------VVADNPVVTSIAESLGRTPAQVALRWG 392 KL FC++ + AY+ LG + V+ ++PV+ ++A+ RTPA +ALR+ Sbjct: 201 KLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQ 260 Query: 391 IQQGQSVLPKSANESRLKENIDLFGWSIPQE 299 +Q+G VL KS NE R+++N+ +F + + E Sbjct: 261 LQRGVVVLAKSYNEQRIRQNVQVFEFQLTSE 291
>AK1E1_MOUSE (Q9DCT1) Aldo-keto reductase family 1 member E1 (EC 1.1.1.-)| Length = 301 Score = 59.3 bits (142), Expect = 7e-09 Identities = 31/84 (36%), Positives = 50/84 (59%), Gaps = 3/84 (3%) Frame = -1 Query: 541 KLRAFCRTNXVHFSAYAPLGRMKV---VADNPVVTSIAESLGRTPAQVALRWGIQQGQSV 371 KL FC V +AY PLG + D+ V+ IA+ G++PAQ+ +R+ IQ+ V Sbjct: 186 KLIDFCHKRNVSVTAYRPLGGSGGGFHLMDDTVIRKIAKKHGKSPAQILIRFQIQRNLIV 245 Query: 370 LPKSANESRLKENIDLFGWSIPQE 299 +PKS SR++ENI +F + + ++ Sbjct: 246 IPKSVTPSRIRENIQVFDFELTEK 269
>S6PD_MALDO (P28475) NADP-dependent D-sorbitol-6-phosphate dehydrogenase (EC| 1.1.1.200) (Aldose-6-phosphate reductase [NADPH]) (NADP-S6PDH) Length = 310 Score = 58.9 bits (141), Expect = 9e-09 Identities = 30/86 (34%), Positives = 49/86 (56%), Gaps = 9/86 (10%) Frame = -1 Query: 529 FCRTNXVHFSAYAPLGRMKV---------VADNPVVTSIAESLGRTPAQVALRWGIQQGQ 377 FC + V +A+ PLG D+PV+ +A+ G++ AQ+ LRWGIQ+ Sbjct: 198 FCMKHGVLPTAHTPLGGAAANKDMFGSVSPLDDPVLNDVAKKYGKSVAQICLRWGIQRKT 257 Query: 376 SVLPKSANESRLKENIDLFGWSIPQE 299 +V+PKS+ RLKEN+++ + + E Sbjct: 258 AVIPKSSKIQRLKENLEVLEFQLSDE 283
>AK1D1_HUMAN (P51857) 3-oxo-5-beta-steroid 4-dehydrogenase (EC 1.3.1.3)| (Delta(4)-3-ketosteroid 5-beta-reductase) (Aldo-keto reductase family 1 member D1) Length = 326 Score = 58.9 bits (141), Expect = 9e-09 Identities = 32/91 (35%), Positives = 53/91 (58%), Gaps = 10/91 (10%) Frame = -1 Query: 541 KLRAFCRTNXVHFSAYAPLGRMK----VVADNP------VVTSIAESLGRTPAQVALRWG 392 KL FC+ + + +AY+PLG + V +P ++ S+ + +T AQ+ LR+ Sbjct: 204 KLLKFCQQHDIVITAYSPLGTSRNPIWVNVSSPPLLKDALLNSLGKRYNKTAAQIVLRFN 263 Query: 391 IQQGQSVLPKSANESRLKENIDLFGWSIPQE 299 IQ+G V+PKS N R+KEN +F +S+ +E Sbjct: 264 IQRGVVVIPKSFNLERIKENFQIFDFSLTEE 294
>MORA_PSEPU (Q02198) Morphine 6-dehydrogenase (EC 1.1.1.218) (Naloxone| reductase) Length = 295 Score = 57.8 bits (138), Expect = 2e-08 Identities = 29/71 (40%), Positives = 44/71 (61%) Frame = -1 Query: 484 GRMKVVADNPVVTSIAESLGRTPAQVALRWGIQQGQSVLPKSANESRLKENIDLFGWSIP 305 GR + D PV+T+IAE+ GR+ AQV LRW Q +PKS N R+ +NID+F +++ Sbjct: 205 GRKHPLTD-PVITTIAEAHGRSAAQVILRWHFQNDVVAIPKSVNPERIAKNIDVFDFALS 263 Query: 304 QELCAKFSEIE 272 A+ E++ Sbjct: 264 DAEMAQLDELD 274
>AK1C1_MACFA (Q95JH7) Aldo-keto reductase family 1 member C1 homolog (EC| 1.-.-.-) (20-alpha-hydroxysteroid dehydrogenase) (EC 1.1.1.149) (20-alpha-HSD) (Dihydrodiol dehydrogenase 1) (DD-1) (DD1) Length = 323 Score = 57.8 bits (138), Expect = 2e-08 Identities = 31/91 (34%), Positives = 54/91 (59%), Gaps = 10/91 (10%) Frame = -1 Query: 541 KLRAFCRTNXVHFSAYAPLGRMK----------VVADNPVVTSIAESLGRTPAQVALRWG 392 KL FC++ + A++ LG + V+ ++PV+ ++A+ RTPA +ALR+ Sbjct: 201 KLLDFCKSKDIVLVAFSALGSHREKPWVDQNSPVLLEDPVLCALAKKHKRTPALIALRYQ 260 Query: 391 IQQGQSVLPKSANESRLKENIDLFGWSIPQE 299 +Q+G VL KS NE R++EN+ +F + + E Sbjct: 261 LQRGVVVLAKSYNEQRIRENMKVFEFQLTSE 291
>ALDX_SPOSA (P27800) Aldehyde reductase 1 (EC 1.1.1.2) (Aldehyde reductase I)| (Alcohol dehydrogenase [NADP+]) (ALR) Length = 322 Score = 57.8 bits (138), Expect = 2e-08 Identities = 32/74 (43%), Positives = 42/74 (56%), Gaps = 4/74 (5%) Frame = -1 Query: 541 KLRAFCRTNXVHFSAYAPLGRMKVVA----DNPVVTSIAESLGRTPAQVALRWGIQQGQS 374 +L A + +H +AY+PLG V A +P + IAE G TPAQV + W I G S Sbjct: 193 ELIAHHKAKNIHITAYSPLGNNTVGAPLLVQHPEIKRIAEKNGCTPAQVLIAWAIVGGHS 252 Query: 373 VLPKSANESRLKEN 332 V+PKS SR+ EN Sbjct: 253 VIPKSVTPSRIGEN 266
>AK1C1_PONPY (Q5REQ0) Aldo-keto reductase family 1 member C1 homolog (EC| 1.-.-.-) (20-alpha-hydroxysteroid dehydrogenase) (EC 1.1.1.149) (20-alpha-HSD) Length = 323 Score = 57.4 bits (137), Expect = 3e-08 Identities = 30/91 (32%), Positives = 54/91 (59%), Gaps = 10/91 (10%) Frame = -1 Query: 541 KLRAFCRTNXVHFSAYAPLGRMK----------VVADNPVVTSIAESLGRTPAQVALRWG 392 KL FC++ + AY+ LG + V+ ++PV+ ++A+ +TPA +ALR+ Sbjct: 201 KLLDFCKSKDIVLVAYSALGSHREEKWVDPNSPVLLEDPVLCALAKKHKQTPALIALRYQ 260 Query: 391 IQQGQSVLPKSANESRLKENIDLFGWSIPQE 299 +Q+G VL KS NE R+++N+ +F + + E Sbjct: 261 LQRGVVVLAKSYNEQRIRQNMQVFDFQLTSE 291
>AK1D1_RABIT (Q9TV64) 3-oxo-5-beta-steroid 4-dehydrogenase (EC 1.3.99.6)| (Delta(4)-3-ketosteroid 5-beta-reductase) (Aldo-keto reductase family 1 member D1) Length = 326 Score = 57.4 bits (137), Expect = 3e-08 Identities = 29/91 (31%), Positives = 51/91 (56%), Gaps = 10/91 (10%) Frame = -1 Query: 541 KLRAFCRTNXVHFSAYAPLGRMK----------VVADNPVVTSIAESLGRTPAQVALRWG 392 KL FC+ + + AY+PLG + + + ++ S+ + +T AQ+ LR+ Sbjct: 204 KLLKFCQQHDIIIVAYSPLGTCRNPMWVNTSLPPLLKDTLLNSLGKKYKKTAAQIVLRFN 263 Query: 391 IQQGQSVLPKSANESRLKENIDLFGWSIPQE 299 +Q+G V+PKS N R+KEN +F +S+ +E Sbjct: 264 VQRGVVVIPKSFNPERIKENFQIFDFSLTEE 294
>DKGA_YERPE (Q8ZI40) 2,5-diketo-D-gluconic acid reductase A (EC 1.1.1.274)| (2,5-DKG reductase A) (2,5-DKGR A) (25DKGR-A) (AKR5C) Length = 277 Score = 57.0 bits (136), Expect = 3e-08 Identities = 25/82 (30%), Positives = 50/82 (60%), Gaps = 1/82 (1%) Frame = -1 Query: 541 KLRAFCRTNXVHFSAYAPLGRM-KVVADNPVVTSIAESLGRTPAQVALRWGIQQGQSVLP 365 +L A+ T+ + +++PL + K V D ++ +A+ +TPAQ+ +RW + G V+P Sbjct: 171 QLHAWNATHHIATESWSPLAQGGKGVFDQEIIRKLAQQYNKTPAQIVIRWHLDSGLIVIP 230 Query: 364 KSANESRLKENIDLFGWSIPQE 299 KS +R++EN ++F + + +E Sbjct: 231 KSVTPARIRENFEVFDFKLQKE 252
>AK1C4_MACFU (Q95JH4) Aldo-keto reductase family 1 member C4 (EC 1.1.1.-)| (Chlordecone reductase) (EC 1.1.1.225) (CDR) (3-alpha-hydroxysteroid dehydrogenase type I) (EC 1.1.1.50) (3-alpha-HSD1) (Dihydrodiol dehydrogenase 4) (DD4) (DD-4) Length = 323 Score = 56.6 bits (135), Expect = 4e-08 Identities = 29/92 (31%), Positives = 54/92 (58%), Gaps = 10/92 (10%) Frame = -1 Query: 544 AKLRAFCRTNXVHFSAYAPLGRMK----------VVADNPVVTSIAESLGRTPAQVALRW 395 +KL FC++ + A++ LG + + ++PV+ ++A+ R+PA +ALR+ Sbjct: 200 SKLLDFCKSKDIVLVAHSALGTQRHKLWVDQNSPALLEDPVLCALAKKHKRSPALIALRY 259 Query: 394 GIQQGQSVLPKSANESRLKENIDLFGWSIPQE 299 +Q+G VL KS NE R++EN+ +F + + E Sbjct: 260 QLQRGVVVLAKSYNEQRIRENVQVFEFQLTSE 291
>AK1C4_MACFA (Q95JH5) Aldo-keto reductase family 1 member C4 (EC 1.1.1.-)| (Chlordecone reductase) (EC 1.1.1.225) (CDR) (3-alpha-hydroxysteroid dehydrogenase type I) (EC 1.1.1.50) (3-alpha-HSD1) (Dihydrodiol dehydrogenase 4) (DD4) (DD-4) Length = 323 Score = 56.6 bits (135), Expect = 4e-08 Identities = 29/92 (31%), Positives = 54/92 (58%), Gaps = 10/92 (10%) Frame = -1 Query: 544 AKLRAFCRTNXVHFSAYAPLGRMK----------VVADNPVVTSIAESLGRTPAQVALRW 395 +KL FC++ + A++ LG + + ++PV+ ++A+ R+PA +ALR+ Sbjct: 200 SKLLDFCKSKDIVLVAHSALGTQRHKLWVDQNSPALLEDPVLCALAKKHKRSPALIALRY 259 Query: 394 GIQQGQSVLPKSANESRLKENIDLFGWSIPQE 299 +Q+G VL KS NE R++EN+ +F + + E Sbjct: 260 QLQRGVVVLAKSYNEQRIRENVQVFEFQLTSE 291
>AK1D1_MOUSE (Q8VCX1) 3-oxo-5-beta-steroid 4-dehydrogenase (EC 1.3.99.6)| (Delta(4)-3-ketosteroid 5-beta-reductase) (Aldo-keto reductase family 1 member D1) Length = 325 Score = 56.6 bits (135), Expect = 4e-08 Identities = 29/91 (31%), Positives = 52/91 (57%), Gaps = 10/91 (10%) Frame = -1 Query: 541 KLRAFCRTNXVHFSAYAPLGRMK----------VVADNPVVTSIAESLGRTPAQVALRWG 392 KL FC+ + + A++PLG + + ++ ++TS+ + +T AQ+ LR+ Sbjct: 203 KLLKFCQQHDIVIVAHSPLGTCRNPSWVNVSSPPLLNDELLTSLGKKYNKTQAQIVLRFN 262 Query: 391 IQQGQSVLPKSANESRLKENIDLFGWSIPQE 299 IQ+G V+PKS R+KEN +F +S+ +E Sbjct: 263 IQRGIVVIPKSFTPERIKENFQIFDFSLTEE 293
>XYL1_TRIRE (Q876L8) NAD(P)H-dependent D-xylose reductase (EC 1.1.1.-) (XR)| Length = 324 Score = 55.8 bits (133), Expect = 7e-08 Identities = 27/88 (30%), Positives = 52/88 (59%), Gaps = 10/88 (11%) Frame = -1 Query: 505 FSAYAPLGRMKV----------VADNPVVTSIAESLGRTPAQVALRWGIQQGQSVLPKSA 356 +S++ P G M++ + D+PV+ ++A+ RTPAQV LRW Q+G +V+PK++ Sbjct: 216 YSSFGPTGFMELDMPRAKSVAPLMDSPVIKALADKHRRTPAQVLLRWATQRGIAVIPKTS 275 Query: 355 NESRLKENIDLFGWSIPQELCAKFSEIE 272 + +N+D + + E AK ++++ Sbjct: 276 RPEVMAQNLDNTSFDLDSEDLAKIADMD 303
>DKGA_SALTY (Q8ZM06) 2,5-diketo-D-gluconic acid reductase A (EC 1.1.1.274)| (2,5-DKG reductase A) (2,5-DKGR A) (25DKGR-A) (AKR5C) Length = 275 Score = 55.8 bits (133), Expect = 7e-08 Identities = 26/92 (28%), Positives = 55/92 (59%), Gaps = 1/92 (1%) Frame = -1 Query: 541 KLRAFCRTNXVHFSAYAPLGRM-KVVADNPVVTSIAESLGRTPAQVALRWGIQQGQSVLP 365 +L A+ T+ + +++PL + + V D V+ +A+ G+TPAQ+ +RW + G V+P Sbjct: 171 QLHAWNATHKIQTESWSPLAQGGEGVFDQKVIRELADKYGKTPAQIVIRWHLDCGLVVIP 230 Query: 364 KSANESRLKENIDLFGWSIPQELCAKFSEIEQ 269 KS SR+ EN ++ + + ++ + ++++Q Sbjct: 231 KSVTPSRIAENFAVWDFRLDKDELGEIAKLDQ 262
>YOF5_CAEEL (Q09632) Probable oxidoreductase ZK1290.5 in chromosome II (EC| 1.-.-.-) Length = 321 Score = 55.5 bits (132), Expect = 1e-07 Identities = 29/82 (35%), Positives = 44/82 (53%) Frame = -1 Query: 544 AKLRAFCRTNXVHFSAYAPLGRMKVVADNPVVTSIAESLGRTPAQVALRWGIQQGQSVLP 365 A L+ +C + Y PL + K + D + IA ++PAQ+ LRW IQQ +P Sbjct: 175 ADLKNYCDELGILTMGYCPLAKGKYLEDE-TLCKIASKYQKSPAQICLRWSIQQNVPTVP 233 Query: 364 KSANESRLKENIDLFGWSIPQE 299 KS + RLKEN ++F + + E Sbjct: 234 KSTDCRRLKENTNVFDFELSAE 255
>DKGA_SALTI (P58744) 2,5-diketo-D-gluconic acid reductase A (EC 1.1.1.274)| (2,5-DKG reductase A) (2,5-DKGR A) (25DKGR-A) (AKR5C) Length = 275 Score = 55.1 bits (131), Expect = 1e-07 Identities = 26/92 (28%), Positives = 54/92 (58%), Gaps = 1/92 (1%) Frame = -1 Query: 541 KLRAFCRTNXVHFSAYAPLGRM-KVVADNPVVTSIAESLGRTPAQVALRWGIQQGQSVLP 365 +L A T+ + +++PL + + V D V+ +A+ G+TPAQ+ +RW + G V+P Sbjct: 171 QLHAXNATHKIQTESWSPLAQGGEGVFDQKVIRELADKYGKTPAQIVIRWHLDCGLVVIP 230 Query: 364 KSANESRLKENIDLFGWSIPQELCAKFSEIEQ 269 KS SR+ EN ++ + + ++ + ++++Q Sbjct: 231 KSVTPSRIAENFAVWDFRLDKDELGEIAKLDQ 262
>DKGA_CORSC (P06632) 2,5-diketo-D-gluconic acid reductase A (EC 1.1.1.274)| (2,5-DKG reductase A) (2,5-DKGR A) (25DKGR-A) (AKR5C) Length = 277 Score = 54.7 bits (130), Expect = 2e-07 Identities = 28/69 (40%), Positives = 42/69 (60%), Gaps = 1/69 (1%) Frame = -1 Query: 511 VHFSAYAPLGRMKV-VADNPVVTSIAESLGRTPAQVALRWGIQQGQSVLPKSANESRLKE 335 V ++ PLG+ K + VT+ A + G+TPAQ LRW +Q+G V PKS RL+E Sbjct: 181 VKIESWGPLGQGKYDLFGAEPVTAAAAAHGKTPAQAVLRWHLQKGFVVFPKSVRRERLEE 240 Query: 334 NIDLFGWSI 308 N+D+F + + Sbjct: 241 NLDVFDFDL 249
>DKGB_YERPE (Q8ZH36) 2,5-diketo-D-gluconic acid reductase B (EC 1.1.1.274)| (2,5-DKG reductase B) (2,5-DKGR B) (25DKGR-B) (AKR5D) Length = 267 Score = 54.3 bits (129), Expect = 2e-07 Identities = 33/105 (31%), Positives = 55/105 (52%) Frame = -1 Query: 529 FCRTNXVHFSAYAPLGRMKVVADNPVVTSIAESLGRTPAQVALRWGIQQGQSVLPKSANE 350 F + N + ++Y L K +A+ PV+ +IAE G TPAQV L W +Q G V+P S Sbjct: 167 FAKQNGIAVTSYMTLAYGKALAE-PVIKTIAEQHGATPAQVILSWAMQLGYGVIPSSTKA 225 Query: 349 SRLKENIDLFGWSIPQELCAKFSEIEQVQSPFSVISVSAENERVL 215 + L N+ + Q+LC +++ ++I+ NER++ Sbjct: 226 ANLASNL------LAQKLCLNAADM-------ALIATLDRNERLV 257
>ALD1_MOUSE (P21300) Aldose reductase-related protein 1 (EC 1.1.1.21) (AR)| (Aldehyde reductase) (VAS deferens androgen-dependent protein) (MVDP) (Aldo-keto reductase family 1 member B7) Length = 315 Score = 53.9 bits (128), Expect = 3e-07 Identities = 29/90 (32%), Positives = 50/90 (55%), Gaps = 9/90 (10%) Frame = -1 Query: 541 KLRAFCRTNXVHFSAYAPLGRMK---------VVADNPVVTSIAESLGRTPAQVALRWGI 389 KL +C++ + +AY+PLG VV + P + IA +T AQV +R+ + Sbjct: 194 KLIQYCQSKGIAVTAYSPLGSPDRPYAKPEDPVVMEIPKIKEIAAKHKKTVAQVLIRFHV 253 Query: 388 QQGQSVLPKSANESRLKENIDLFGWSIPQE 299 Q+ V+PKS SR++EN+ +F + + +E Sbjct: 254 QRNVVVIPKSVTPSRIQENLQVFDFQLSEE 283
>CRO_RANCA (P17264) Rho crystallin| Length = 323 Score = 53.5 bits (127), Expect = 4e-07 Identities = 28/91 (30%), Positives = 51/91 (56%), Gaps = 10/91 (10%) Frame = -1 Query: 541 KLRAFCRTNXVHFSAYAPLGR----------MKVVADNPVVTSIAESLGRTPAQVALRWG 392 KL ++C++ + Y+ LG + V+ D+P++ IA RT A+VA+R+ Sbjct: 201 KLHSYCKSKDIVLVTYSVLGSHRDRNWVDLSLPVLLDDPILNKIAAKYNRTSAEVAMRFI 260 Query: 391 IQQGQSVLPKSANESRLKENIDLFGWSIPQE 299 +Q+G VL KS +R+K+N+ +F + + E Sbjct: 261 LQKGIVVLAKSFTPARIKQNLGVFEFELKPE 291
>GCY_YEAST (P14065) GCY protein (EC 1.1.1.-)| Length = 312 Score = 53.5 bits (127), Expect = 4e-07 Identities = 26/71 (36%), Positives = 38/71 (53%), Gaps = 1/71 (1%) Frame = -1 Query: 529 FCRTNXVHFSAYAPLGRMKV-VADNPVVTSIAESLGRTPAQVALRWGIQQGQSVLPKSAN 353 FC++ + AY+PLG + PV+ IA+ P V + W +Q+G VLPKS N Sbjct: 208 FCKSKGIVVEAYSPLGSTDAPLLKEPVILEIAKKNNVQPGHVVISWHVQRGYVVLPKSVN 267 Query: 352 ESRLKENIDLF 320 R+K N +F Sbjct: 268 PDRIKTNRKIF 278
>XYL1_PICGU (O94735) NADPH-dependent D-xylose reductase (EC 1.1.1.-) (XR)| Length = 317 Score = 53.1 bits (126), Expect = 5e-07 Identities = 25/69 (36%), Positives = 44/69 (63%) Frame = -1 Query: 478 MKVVADNPVVTSIAESLGRTPAQVALRWGIQQGQSVLPKSANESRLKENIDLFGWSIPQE 299 +K + ++ V+ S+A + +TPAQV LRW Q+G +V+PKS N RL N+ + + + QE Sbjct: 231 VKPLFEHDVIKSVAGKVKKTPAQVLLRWATQRGLAVIPKSNNPDRLLSNLKVNDFDLSQE 290 Query: 298 LCAKFSEIE 272 + S+++ Sbjct: 291 DFQEISKLD 299
>CRO_RANTE (P02532) Rho crystallin| Length = 323 Score = 52.8 bits (125), Expect = 6e-07 Identities = 26/91 (28%), Positives = 51/91 (56%), Gaps = 10/91 (10%) Frame = -1 Query: 541 KLRAFCRTNXVHFSAYAPLGR----------MKVVADNPVVTSIAESLGRTPAQVALRWG 392 KL ++C++ + Y+ LG + V+ D+P++ +A RT A++A+R+ Sbjct: 201 KLHSYCKSKDIVLVTYSVLGSHRDRNWVDLSLPVLLDDPILNKVAAKYNRTSAEIAMRFI 260 Query: 391 IQQGQSVLPKSANESRLKENIDLFGWSIPQE 299 +Q+G VL KS +R+K+N+ +F + + E Sbjct: 261 LQKGIVVLAKSFTPARIKQNLGVFEFELKPE 291
>ALD2_MOUSE (P45377) Aldose reductase-related protein 2 (EC 1.1.1.21) (AR)| (Aldehyde reductase) (Fibroblast growth factor-regulated protein) (FR-1 protein) Length = 315 Score = 52.8 bits (125), Expect = 6e-07 Identities = 29/90 (32%), Positives = 48/90 (53%), Gaps = 9/90 (10%) Frame = -1 Query: 541 KLRAFCRTNXVHFSAYAPLGRMK---------VVADNPVVTSIAESLGRTPAQVALRWGI 389 KL +C + + +AY+PLG + ++P + IA +T AQV +R+ I Sbjct: 194 KLIQYCHSKGISVTAYSPLGSPDRPSAKPEDPSLLEDPKIKEIAAKHEKTSAQVLIRFHI 253 Query: 388 QQGQSVLPKSANESRLKENIDLFGWSIPQE 299 Q+ V+PKS SR++ENI +F + + E Sbjct: 254 QRNVVVIPKSVTPSRIQENIQVFDFQLSDE 283
>ALDR_BOVIN (P16116) Aldose reductase (EC 1.1.1.21) (AR) (Aldehyde reductase)| (20-alpha-hydroxysteroid dehydrogenase) (EC 1.1.1.149) (20-alpha-HSD) Length = 315 Score = 52.0 bits (123), Expect = 1e-06 Identities = 27/90 (30%), Positives = 48/90 (53%), Gaps = 9/90 (10%) Frame = -1 Query: 541 KLRAFCRTNXVHFSAYAPLGRMK---------VVADNPVVTSIAESLGRTPAQVALRWGI 389 KL +C + + +AY+PLG + ++P + +IA+ +T AQV +R+ I Sbjct: 194 KLIQYCNSKGIVVTAYSPLGSPDRPWAKPEDPSILEDPRIKAIADKYNKTTAQVLIRFPI 253 Query: 388 QQGQSVLPKSANESRLKENIDLFGWSIPQE 299 Q+ V+PKS R+ EN +F + + +E Sbjct: 254 QRNLIVIPKSVTPERIAENFQVFDFELDKE 283
>YPR1_YEAST (Q12458) Putative reductase 1 (EC 1.1.1.-)| Length = 312 Score = 52.0 bits (123), Expect = 1e-06 Identities = 29/102 (28%), Positives = 50/102 (49%), Gaps = 1/102 (0%) Frame = -1 Query: 541 KLRAFCRTNXVHFSAYAPLGRMKV-VADNPVVTSIAESLGRTPAQVALRWGIQQGQSVLP 365 +L AFC+ + AY+P G + + +A+ G PAQ+ + W IQ+G VL Sbjct: 204 ELIAFCKEKGIVVEAYSPFGSANAPLLKEQAIIDMAKKHGVEPAQLIISWSIQRGYVVLA 263 Query: 364 KSANESRLKENIDLFGWSIPQELCAKFSEIEQVQSPFSVISV 239 KS N R+ N +F ++P++ S + +V V+ + Sbjct: 264 KSVNPERIVSNFKIF--TLPEDDFKTISNLSKVHGTKRVVDM 303
>AK1CD_MOUSE (Q8VC28) Aldo-keto reductase family 1 member C13 (EC 1.1.1.-)| Length = 323 Score = 51.2 bits (121), Expect = 2e-06 Identities = 28/91 (30%), Positives = 50/91 (54%), Gaps = 10/91 (10%) Frame = -1 Query: 541 KLRAFCRTNXVHFSAYAPLGRMK----------VVADNPVVTSIAESLGRTPAQVALRWG 392 KL +C + + AY LG + V+ ++PV+ +A+ R+PA +ALR+ Sbjct: 201 KLLDYCESKDIVLVAYGALGTQRYKEWVDQNSPVLLNDPVLCDVAKKNKRSPALIALRYL 260 Query: 391 IQQGQSVLPKSANESRLKENIDLFGWSIPQE 299 IQ+G L +S E+ ++EN+ +FG+ + E Sbjct: 261 IQRGIVPLAQSFKENEMRENLQVFGFQLSPE 291
>AK1D1_RAT (P31210) 3-oxo-5-beta-steroid 4-dehydrogenase (EC 1.3.99.6)| (Delta(4)-3-ketosteroid 5-beta-reductase) (Aldo-keto reductase family 1 member D1) Length = 326 Score = 51.2 bits (121), Expect = 2e-06 Identities = 28/77 (36%), Positives = 45/77 (58%), Gaps = 10/77 (12%) Frame = -1 Query: 499 AYAPLGRMK----VVADNP------VVTSIAESLGRTPAQVALRWGIQQGQSVLPKSANE 350 AY+PLG + V +P ++TS+ + +T AQ+ LR+ IQ+G V+PKS Sbjct: 218 AYSPLGTCRNPLWVNVSSPPLLKDELLTSLGKKYNKTQAQIVLRFDIQRGLVVIPKSTTP 277 Query: 349 SRLKENIDLFGWSIPQE 299 R+KEN +F +S+ +E Sbjct: 278 ERIKENFQIFDFSLTKE 294
>XYL1_CANPA (Q6Y0Z3) NADH-dependent D-xylose reductase (EC 1.1.1.175) (XR)| Length = 324 Score = 50.1 bits (118), Expect = 4e-06 Identities = 22/67 (32%), Positives = 43/67 (64%) Frame = -1 Query: 472 VVADNPVVTSIAESLGRTPAQVALRWGIQQGQSVLPKSANESRLKENIDLFGWSIPQELC 293 V+ + P V SIA+ G++PAQV LR+ Q+G +V+P+S + R+ +N+ + + + Q+ Sbjct: 240 VLLEEPTVKSIADKHGKSPAQVLLRYQTQRGIAVIPRSNSPDRMAQNLSVIDFELTQDDL 299 Query: 292 AKFSEIE 272 +E++ Sbjct: 300 QAIAELD 306
>AK1BA_HUMAN (O60218) Aldo-keto reductase family 1 member B10 (EC 1.1.1.-)| (Aldose reductase-like) (ARL-1) (Small intestine reductase) (SI reductase) (Aldose reductase-related protein) (ARP) (hARP) Length = 316 Score = 50.1 bits (118), Expect = 4e-06 Identities = 28/90 (31%), Positives = 47/90 (52%), Gaps = 9/90 (10%) Frame = -1 Query: 541 KLRAFCRTNXVHFSAYAPLGRMK---------VVADNPVVTSIAESLGRTPAQVALRWGI 389 KL +C + + +AY+PLG + ++P + IA +T AQV +R+ I Sbjct: 195 KLIQYCHSKGITVTAYSPLGSPDRPWAKPEDPSLLEDPKIKEIAAKHKKTAAQVLIRFHI 254 Query: 388 QQGQSVLPKSANESRLKENIDLFGWSIPQE 299 Q+ V+PKS +R+ ENI +F + + E Sbjct: 255 QRNVIVIPKSVTPARIVENIQVFDFKLSDE 284
>XYL1_PICST (P31867) NAD(P)H-dependent D-xylose reductase (EC 1.1.1.-) (XR)| Length = 318 Score = 49.7 bits (117), Expect = 5e-06 Identities = 28/103 (27%), Positives = 52/103 (50%), Gaps = 13/103 (12%) Frame = -1 Query: 541 KLRAFCRTNXVHFSAYAPLGRMKVVA-------------DNPVVTSIAESLGRTPAQVAL 401 +L F ++ + +AY+ G V +N + +IA G++PAQV L Sbjct: 198 RLIEFAQSRGIAVTAYSSFGPQSFVELNQGRALNTSPLFENETIKAIAAKHGKSPAQVLL 257 Query: 400 RWGIQQGQSVLPKSANESRLKENIDLFGWSIPQELCAKFSEIE 272 RW Q+G +++PKS RL EN D+ + + ++ A ++++ Sbjct: 258 RWSSQRGIAIIPKSNTVPRLLENKDVNSFDLDEQDFADIAKLD 300
>ALDR_MOUSE (P45376) Aldose reductase (EC 1.1.1.21) (AR) (Aldehyde reductase)| Length = 315 Score = 49.7 bits (117), Expect = 5e-06 Identities = 27/90 (30%), Positives = 47/90 (52%), Gaps = 9/90 (10%) Frame = -1 Query: 541 KLRAFCRTNXVHFSAYAPLGRMK---------VVADNPVVTSIAESLGRTPAQVALRWGI 389 KL +C + + +AY+PLG + ++P + +IA +T AQV +R+ I Sbjct: 194 KLIEYCHSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAKYNKTTAQVLIRFPI 253 Query: 388 QQGQSVLPKSANESRLKENIDLFGWSIPQE 299 Q+ V+PKS R+ EN+ +F + + E Sbjct: 254 QRNLVVIPKSVTPVRIAENLKVFDFEVSSE 283
>YDG7_SCHPO (Q10494) Probable oxidoreductase C26F1.07 in chromosome I (EC| 1.-.-.-) Length = 321 Score = 49.7 bits (117), Expect = 5e-06 Identities = 25/70 (35%), Positives = 39/70 (55%), Gaps = 10/70 (14%) Frame = -1 Query: 511 VHFSAYAPLGRMKVVADNPV--------VTSIAESLGR--TPAQVALRWGIQQGQSVLPK 362 +H +AY+P G + ++ + + IA+S G T A +A+ W I +G SV+PK Sbjct: 210 IHVTAYSPFGNQNTIYESKIPKLIEHETIQKIAKSKGEGVTGATIAVSWAITRGTSVIPK 269 Query: 361 SANESRLKEN 332 S NE R+K N Sbjct: 270 SVNEQRIKSN 279
>DIDH_RAT (P23457) 3-alpha-hydroxysteroid dehydrogenase (EC 1.1.1.213)| (3-alpha-HSD) (Hydroxyprostaglandin dehydrogenase) Length = 322 Score = 49.3 bits (116), Expect = 7e-06 Identities = 28/92 (30%), Positives = 50/92 (54%), Gaps = 10/92 (10%) Frame = -1 Query: 544 AKLRAFCRTNXVHFSAYAPLGRMK----------VVADNPVVTSIAESLGRTPAQVALRW 395 +K+ +C++ + +Y LG + V+ D+PV+ +IA+ +TPA VALR+ Sbjct: 200 SKMLDYCKSKDIILVSYCTLGSSRDKTWVDQKSPVLLDDPVLCAIAKKYKQTPALVALRY 259 Query: 394 GIQQGQSVLPKSANESRLKENIDLFGWSIPQE 299 +Q+G L +S N R+KE +F + + E Sbjct: 260 QLQRGVVPLIRSFNAKRIKELTQVFEFQLASE 291
>ALDR_PIG (P80276) Aldose reductase (EC 1.1.1.21) (AR) (Aldehyde reductase)| Length = 315 Score = 48.9 bits (115), Expect = 9e-06 Identities = 26/90 (28%), Positives = 47/90 (52%), Gaps = 9/90 (10%) Frame = -1 Query: 541 KLRAFCRTNXVHFSAYAPLGRMK---------VVADNPVVTSIAESLGRTPAQVALRWGI 389 KL +C++ + +AY+PLG + ++P + +IA +T AQV +R+ + Sbjct: 194 KLIEYCKSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAKYNKTTAQVLIRFPM 253 Query: 388 QQGQSVLPKSANESRLKENIDLFGWSIPQE 299 Q+ V+PKS R+ EN +F + + E Sbjct: 254 QRNLIVIPKSVTPERIAENFQVFDFELSPE 283
>ALDR_RAT (P07943) Aldose reductase (EC 1.1.1.21) (AR) (Aldehyde reductase)| Length = 315 Score = 48.5 bits (114), Expect = 1e-05 Identities = 27/90 (30%), Positives = 45/90 (50%), Gaps = 9/90 (10%) Frame = -1 Query: 541 KLRAFCRTNXVHFSAYAPLGRMK---------VVADNPVVTSIAESLGRTPAQVALRWGI 389 KL +C + +AY+PLG + ++P + IA +T AQV +R+ I Sbjct: 194 KLIEYCHCKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKEIAAKYNKTTAQVLIRFPI 253 Query: 388 QQGQSVLPKSANESRLKENIDLFGWSIPQE 299 Q+ V+PKS +R+ EN +F + + E Sbjct: 254 QRNLVVIPKSVTPARIAENFKVFDFELSNE 283
>ALDR_RABIT (P15122) Aldose reductase (EC 1.1.1.21) (AR) (Aldehyde reductase)| Length = 315 Score = 48.5 bits (114), Expect = 1e-05 Identities = 26/90 (28%), Positives = 48/90 (53%), Gaps = 9/90 (10%) Frame = -1 Query: 541 KLRAFCRTNXVHFSAYAPLGRMK---------VVADNPVVTSIAESLGRTPAQVALRWGI 389 KL +C + + +AY+PLG + ++P + +IA+ +T AQV +R+ + Sbjct: 194 KLIQYCHSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIADKHKKTTAQVLIRFPM 253 Query: 388 QQGQSVLPKSANESRLKENIDLFGWSIPQE 299 Q+ V+PKS +R+ EN +F + + E Sbjct: 254 QRNLVVIPKSVTPARIAENFQVFDFELSSE 283
>ALD2_CRIGR (O08782) Aldose reductase-related protein 2 (EC 1.1.1.21) (AR)| (Aldehyde reductase) (Aldo-keto reductase) Length = 315 Score = 48.1 bits (113), Expect = 2e-05 Identities = 26/90 (28%), Positives = 46/90 (51%), Gaps = 9/90 (10%) Frame = -1 Query: 541 KLRAFCRTNXVHFSAYAPLGRMK---------VVADNPVVTSIAESLGRTPAQVALRWGI 389 KL +C + + +AY+PLG + ++P + IA +T AQV +R+ I Sbjct: 194 KLIEYCHSKGITVTAYSPLGSPNRPWAKPEDPSLLEDPKIKEIAAKHKKTSAQVLIRFHI 253 Query: 388 QQGQSVLPKSANESRLKENIDLFGWSIPQE 299 Q+ V+PKS +R+ EN +F + + + Sbjct: 254 QRNVVVIPKSVTPARIHENFQVFDFQLSDQ 283
>XYL2_CANTR (P87039) NADPH-dependent D-xylose reductase II,III (EC 1.1.1.-)| (XR) Length = 324 Score = 48.1 bits (113), Expect = 2e-05 Identities = 20/55 (36%), Positives = 36/55 (65%) Frame = -1 Query: 463 DNPVVTSIAESLGRTPAQVALRWGIQQGQSVLPKSANESRLKENIDLFGWSIPQE 299 ++ + SIA+ G++PAQV LRW Q+ +V+PKS N RL +N+ + + + ++ Sbjct: 243 EHETIKSIADKHGKSPAQVLLRWATQRNIAVIPKSNNPERLAQNLSVVDFDLTKD 297
>DKGB_ECOLI (P30863) 2,5-diketo-D-gluconic acid reductase B (EC 1.1.1.274)| (2,5-DKG reductase B) (2,5-DKGR B) (25DKGR-B) (AKR5D) Length = 267 Score = 47.8 bits (112), Expect = 2e-05 Identities = 24/71 (33%), Positives = 38/71 (53%) Frame = -1 Query: 541 KLRAFCRTNXVHFSAYAPLGRMKVVADNPVVTSIAESLGRTPAQVALRWGIQQGQSVLPK 362 K+ A+ + + +H ++Y L K + D V+ IA TPAQV L W + +G SV+P Sbjct: 163 KVVAWAKQHGIHITSYMTLAYGKALKDE-VIARIAAKHNATPAQVILAWAMGEGYSVIPS 221 Query: 361 SANESRLKENI 329 S L+ N+ Sbjct: 222 STKRKNLESNL 232
>DKGB_ECO57 (Q8X7Z7) 2,5-diketo-D-gluconic acid reductase B (EC 1.1.1.274)| (2,5-DKG reductase B) (2,5-DKGR B) (25DKGR-B) (AKR5D) Length = 267 Score = 47.8 bits (112), Expect = 2e-05 Identities = 24/71 (33%), Positives = 38/71 (53%) Frame = -1 Query: 541 KLRAFCRTNXVHFSAYAPLGRMKVVADNPVVTSIAESLGRTPAQVALRWGIQQGQSVLPK 362 K+ A+ + + +H ++Y L K + D V+ IA TPAQV L W + +G SV+P Sbjct: 163 KVVAWAKQHGIHITSYMTLAYGKALKDE-VIARIAAKHNATPAQVILAWAMGEGYSVIPS 221 Query: 361 SANESRLKENI 329 S L+ N+ Sbjct: 222 STKRENLESNL 232
>AK1CD_MESAU (P82809) Aldo-keto reductase family 1 member C13 (EC 1.1.1.-)| (Morphine 6-dehydrogenase) (EC 1.1.1.218) Length = 322 Score = 47.8 bits (112), Expect = 2e-05 Identities = 27/92 (29%), Positives = 50/92 (54%), Gaps = 10/92 (10%) Frame = -1 Query: 544 AKLRAFCRTNXVHFSAYAPLGRMK----------VVADNPVVTSIAESLGRTPAQVALRW 395 +KL +C++ + A+ LG + V+ ++PV+ A+ R+PA +ALR+ Sbjct: 200 SKLLDYCKSKDIVLVAFGALGTQRYKEWVDQDSPVLLNDPVLCGGAKXXXRSPALIALRY 259 Query: 394 GIQQGQSVLPKSANESRLKENIDLFGWSIPQE 299 +Q+G L +S ES +KEN+ +F + + E Sbjct: 260 LVQRGVVPLAQSFYESEMKENLQVFEFQLSPE 291
>YJ66_YEAST (P47137) Probable oxidoreductase YJR096W (EC 1.-.-.-)| Length = 282 Score = 47.4 bits (111), Expect = 3e-05 Identities = 23/81 (28%), Positives = 42/81 (51%) Frame = -1 Query: 541 KLRAFCRTNXVHFSAYAPLGRMKVVADNPVVTSIAESLGRTPAQVALRWGIQQGQSVLPK 362 +L +C++ + A+APL + NP + + + + R P QV +RW +Q G LPK Sbjct: 181 ELADYCKSKGLVVEAFAPLCHGYKMT-NPDLLKVCKEVDRNPGQVLIRWSLQHGYLPLPK 239 Query: 361 SANESRLKENIDLFGWSIPQE 299 + RL+ N+ + + + E Sbjct: 240 TKTVKRLEGNLAAYNFELSDE 260
>ALDR_HUMAN (P15121) Aldose reductase (EC 1.1.1.21) (AR) (Aldehyde reductase)| Length = 315 Score = 46.6 bits (109), Expect = 5e-05 Identities = 25/90 (27%), Positives = 47/90 (52%), Gaps = 9/90 (10%) Frame = -1 Query: 541 KLRAFCRTNXVHFSAYAPLGRMK---------VVADNPVVTSIAESLGRTPAQVALRWGI 389 KL +C++ + +AY+PLG + ++P + +IA +T AQV +R+ + Sbjct: 194 KLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAKHNKTTAQVLIRFPM 253 Query: 388 QQGQSVLPKSANESRLKENIDLFGWSIPQE 299 Q+ V+PKS R+ EN +F + + + Sbjct: 254 QRNLVVIPKSVTPERIAENFKVFDFELSSQ 283
>XYL1_CANTR (O13283) NAD(P)H-dependent D-xylose reductase I,II (EC 1.1.1.-)| (XR) Length = 324 Score = 45.8 bits (107), Expect = 8e-05 Identities = 19/55 (34%), Positives = 35/55 (63%) Frame = -1 Query: 463 DNPVVTSIAESLGRTPAQVALRWGIQQGQSVLPKSANESRLKENIDLFGWSIPQE 299 ++ + IA+ G++PAQV LRW Q+ +V+PKS N RL +N+ + + + ++ Sbjct: 243 EHETIKLIADKHGKSPAQVLLRWATQRNIAVIPKSNNPERLAQNLSVVDFDLTKD 297
>GRE3_YEAST (P38715) NADPH-dependent aldose reductase GRE3 (EC 1.1.1.21)| (NADPH-dependent aldo-keto reductase GRE3) (NADPH-dependent methylglyoxal reductase GRE3) (EC 1.1.1.-) (Xylose reductase) (EC 1.1.1.-) (Genes de respuesta a estres protein 3) Length = 327 Score = 43.5 bits (101), Expect = 4e-04 Identities = 23/83 (27%), Positives = 43/83 (51%), Gaps = 14/83 (16%) Frame = -1 Query: 529 FCRTNXVHFSAYAPLGRMKVVA-------------DNPVVTSIAESL-GRTPAQVALRWG 392 FC+ + + AY+ G + +N V+ ++++ G T +QV LRW Sbjct: 207 FCKLHDIQVVAYSSFGPQSFIEMDLQLAKTTPTLFENDVIKKVSQNHPGSTTSQVLLRWA 266 Query: 391 IQQGQSVLPKSANESRLKENIDL 323 Q+G +V+PKS+ + RL N+++ Sbjct: 267 TQRGIAVIPKSSKKERLLGNLEI 289
>DKGB_SALTY (Q8ZRM7) 2,5-diketo-D-gluconic acid reductase B (EC 1.1.1.274)| (2,5-DKG reductase B) (2,5-DKGR B) (25DKGR-B) (AKR5D) Length = 267 Score = 43.1 bits (100), Expect = 5e-04 Identities = 22/71 (30%), Positives = 36/71 (50%) Frame = -1 Query: 541 KLRAFCRTNXVHFSAYAPLGRMKVVADNPVVTSIAESLGRTPAQVALRWGIQQGQSVLPK 362 K+ + + + +H ++Y L K + D V+ IA TPAQV L W + +G SV+P Sbjct: 163 KVVDWAKAHGIHITSYMTLAYGKALKDE-VIARIAAKHNATPAQVILAWAMGEGYSVIPS 221 Query: 361 SANESRLKENI 329 S L ++ Sbjct: 222 STRRENLASSL 232
>DKGB_SALTI (Q8Z988) 2,5-diketo-D-gluconic acid reductase B (EC 1.1.1.274)| (2,5-DKG reductase B) (2,5-DKGR B) (25DKGR-B) (AKR5D) Length = 267 Score = 43.1 bits (100), Expect = 5e-04 Identities = 22/71 (30%), Positives = 35/71 (49%) Frame = -1 Query: 541 KLRAFCRTNXVHFSAYAPLGRMKVVADNPVVTSIAESLGRTPAQVALRWGIQQGQSVLPK 362 K+ + + + +H ++Y L K + D V+ IA TP QV L W + +G SV+P Sbjct: 163 KVVDWAKAHGIHITSYMTLAYGKALKDE-VIARIAVKHNATPVQVILAWAMGEGYSVIPS 221 Query: 361 SANESRLKENI 329 S L N+ Sbjct: 222 STRRENLASNL 232
>XYL1_PACTA (P78736) NAD(P)H-dependent D-xylose reductase (EC 1.1.1.-) (XR)| Length = 318 Score = 43.1 bits (100), Expect = 5e-04 Identities = 20/65 (30%), Positives = 40/65 (61%) Frame = -1 Query: 463 DNPVVTSIAESLGRTPAQVALRWGIQQGQSVLPKSANESRLKENIDLFGWSIPQELCAKF 284 +N +T+IA G+TP QV LRW Q+G +++PKS + L N+ + + + +E + Sbjct: 237 ENKTITTIAAKHGKTPFQVLLRWVNQRGIAIIPKSTFPNTLAVNLHVDEFDLTKEDFEEI 296 Query: 283 SEIEQ 269 +++++ Sbjct: 297 AKLDR 301
>XYL1_CANTE (O74237) NAD(P)H-dependent D-xylose reductase (EC 1.1.1.-) (XR)| Length = 322 Score = 42.7 bits (99), Expect = 7e-04 Identities = 31/105 (29%), Positives = 47/105 (44%), Gaps = 13/105 (12%) Frame = -1 Query: 541 KLRAFCRTNXVHFSAYAPLGRMKVVADNP-------------VVTSIAESLGRTPAQVAL 401 KL F + V +AY+ G V N + +IA +TPA+V L Sbjct: 202 KLIEFAQKAGVTITAYSSFGPQSFVEMNQGRALNTPTLFAHDTIKAIAAKYNKTPAEVLL 261 Query: 400 RWGIQQGQSVLPKSANESRLKENIDLFGWSIPQELCAKFSEIEQV 266 RW Q+G +V+PKS RL +N + + +E F EI ++ Sbjct: 262 RWAAQRGIAVIPKSNLPERLVQNRSFNTFDLTKE---DFEEIAKL 303
>ARA1_YEAST (P38115) D-arabinose dehydrogenase [NAD(P)+] heavy chain (EC| 1.1.1.117) Length = 344 Score = 42.0 bits (97), Expect = 0.001 Identities = 24/77 (31%), Positives = 42/77 (54%), Gaps = 5/77 (6%) Frame = -1 Query: 541 KLRAFCRTNXVHFSAYAPLG-----RMKVVADNPVVTSIAESLGRTPAQVALRWGIQQGQ 377 +LR FC + + +AY+PLG +K+ P+V +AE T + + + I+QG Sbjct: 225 ELRKFCFMHDILLTAYSPLGSHGAPNLKI----PLVKKLAEKYNVTGNDLLISYHIRQGT 280 Query: 376 SVLPKSANESRLKENID 326 V+P+S N R+ +I+ Sbjct: 281 IVIPRSLNPVRISSSIE 297
>XYL1_CANSH (Q9P430) NAD(P)H-dependent D-xylose reductase (EC 1.1.1.-) (XR)| Length = 323 Score = 41.2 bits (95), Expect = 0.002 Identities = 20/64 (31%), Positives = 37/64 (57%) Frame = -1 Query: 463 DNPVVTSIAESLGRTPAQVALRWGIQQGQSVLPKSANESRLKENIDLFGWSIPQELCAKF 284 ++ V+ +IA + PA+V LRW Q+G +V+PKS RL +N + + +E + Sbjct: 242 EHDVIKAIAAKHNKVPAEVLLRWSAQRGIAVIPKSNLPERLVQNRSFNDFELTKEDFEEI 301 Query: 283 SEIE 272 S+++ Sbjct: 302 SKLD 305
>XYL1_KLULA (P49378) NAD(P)H-dependent D-xylose reductase (EC 1.1.1.-) (XR)| Length = 329 Score = 41.2 bits (95), Expect = 0.002 Identities = 18/45 (40%), Positives = 28/45 (62%) Frame = -1 Query: 463 DNPVVTSIAESLGRTPAQVALRWGIQQGQSVLPKSANESRLKENI 329 ++ + SIA TP QV LRW Q G +++PKS+ + RL +N+ Sbjct: 245 EHDTIKSIASKHKVTPQQVLLRWATQNGIAIIPKSSKKERLLDNL 289
>DTDH_MUCMU (Q01213) 4-dihydromethyl-trisporate dehydrogenase (EC 1.1.1.-)| (4-dihydromethyl-TA dehydrogenase) Length = 321 Score = 38.5 bits (88), Expect = 0.012 Identities = 17/51 (33%), Positives = 29/51 (56%) Frame = -1 Query: 451 VTSIAESLGRTPAQVALRWGIQQGQSVLPKSANESRLKENIDLFGWSIPQE 299 V S+A+ + QV LRW + + +V+PKS N R+K N+++ + E Sbjct: 243 VKSVADKHNVSTGQVLLRWALDREFAVIPKSVNAGRMKANLEILDIKLDAE 293
>YDBC_ECOLI (P25906) Putative oxidoreductase ydbC (EC 1.-.-.-)| Length = 286 Score = 37.4 bits (85), Expect = 0.027 Identities = 20/63 (31%), Positives = 38/63 (60%), Gaps = 2/63 (3%) Frame = -1 Query: 511 VHFSAYAPLGRMKVVADNPVVTSIAESLGRTPAQVALRWGIQQGQSVL--PKSANESRLK 338 + + + PLG + + ++ +A SLG TP QVAL W +Q+ ++L P +++ + L+ Sbjct: 204 IAYVPFFPLGGFTPLQSS-TLSDVAASLGATPMQVALAWLLQRSPNILLIPGTSSVAHLR 262 Query: 337 ENI 329 EN+ Sbjct: 263 ENM 265
>YEAE_ECOLI (P76234) Hypothetical protein yeaE| Length = 284 Score = 35.8 bits (81), Expect = 0.080 Identities = 25/74 (33%), Positives = 40/74 (54%), Gaps = 5/74 (6%) Frame = -1 Query: 538 LRAFCRTNXVHFSAYAPL---GRMKV-VADNPVVTSIAESLGRTPAQVALRWGI-QQGQS 374 L +C+ + AY+PL GR++ + N VV IA + + AQV L W I QG Sbjct: 179 LLPWCQQQQMPVMAYSPLAQAGRLRNGLLKNAVVNEIAHAHNISAAQVLLAWVISHQGVM 238 Query: 373 VLPKSANESRLKEN 332 +PK+A + +++N Sbjct: 239 AIPKAATIAHVQQN 252
>MAST2_MOUSE (Q60592) Microtubule-associated serine/threonine-protein kinase 2 (EC| 2.7.11.1) Length = 1734 Score = 32.0 bits (71), Expect = 1.1 Identities = 23/79 (29%), Positives = 33/79 (41%), Gaps = 8/79 (10%) Frame = +1 Query: 322 TGQCSPSTSTHSHF*EARSDPAGCPIVERPV--------PAFSPSSRLSMSPPGYPRRLS 477 +G+ P + THSH RS P G + V + SPSS + SP G Sbjct: 1195 SGESGPGSPTHSHSLSPRSPPQGYRVAPDAVHSVGGNSSQSSSPSSSVPSSPAG------ 1248 Query: 478 SYLAAHTQRNELHWCGRRL 534 + HT+ + LH +L Sbjct: 1249 ---SGHTRPSSLHGLAPKL 1264
>TNR1A_MOUSE (P25118) Tumor necrosis factor receptor superfamily member 1A| precursor (p60) (TNF-R1) (TNF-RI) (TNFR-I) (p55) Length = 454 Score = 30.4 bits (67), Expect = 3.3 Identities = 16/40 (40%), Positives = 22/40 (55%), Gaps = 4/40 (10%) Frame = +1 Query: 373 RSDPAGCPIVERPVPAFSPSS----RLSMSPPGYPRRLSS 480 + + AG P+ P PAFSP+S L S PG+ +SS Sbjct: 256 KEEKAGKPLTPAPSPAFSPTSGFNPTLGFSTPGFSSPVSS 295
>CH60_BRUSU (Q8FX87) 60 kDa chaperonin (Protein Cpn60) (groEL protein)| Length = 546 Score = 30.4 bits (67), Expect = 3.3 Identities = 27/113 (23%), Positives = 49/113 (43%), Gaps = 3/113 (2%) Frame = -1 Query: 427 GRTPAQVALRWGIQQGQSVLPKSANESRLKENIDLFGWSIPQELCAKFSEIEQVQSPFSV 248 G T A V + +Q+G + N LK IDL + EL K +I + V Sbjct: 88 GTTTATVLGQAIVQEGAKAVAAGMNPMDLKRGIDLAVNEVVAELLKKAKKINTSEEVAQV 147 Query: 247 ISVSAENERVLR---GEQVKRIRNDSLVHPRSIYKTMDELWDGEI*LKISAGI 98 ++SA E + E ++++ N+ ++ T++E E L++ G+ Sbjct: 148 GTISANGEAEIGKMIAEAMQKVGNEGVI-------TVEEAKTAETELEVVEGM 193
>CH60_BRUME (Q8YB53) 60 kDa chaperonin (Protein Cpn60) (groEL protein)| Length = 546 Score = 30.4 bits (67), Expect = 3.3 Identities = 27/113 (23%), Positives = 49/113 (43%), Gaps = 3/113 (2%) Frame = -1 Query: 427 GRTPAQVALRWGIQQGQSVLPKSANESRLKENIDLFGWSIPQELCAKFSEIEQVQSPFSV 248 G T A V + +Q+G + N LK IDL + EL K +I + V Sbjct: 88 GTTTATVLGQAIVQEGAKAVAAGMNPMDLKRGIDLAVNEVVAELLKKAKKINTSEEVAQV 147 Query: 247 ISVSAENERVLR---GEQVKRIRNDSLVHPRSIYKTMDELWDGEI*LKISAGI 98 ++SA E + E ++++ N+ ++ T++E E L++ G+ Sbjct: 148 GTISANGEAEIGKMIAEAMQKVGNEGVI-------TVEEAKTAETELEVVEGM 193
>CH60_BRUAB (P25967) 60 kDa chaperonin (Protein Cpn60) (groEL protein) (Hsp60)| (BA60K) Length = 546 Score = 30.4 bits (67), Expect = 3.3 Identities = 27/113 (23%), Positives = 49/113 (43%), Gaps = 3/113 (2%) Frame = -1 Query: 427 GRTPAQVALRWGIQQGQSVLPKSANESRLKENIDLFGWSIPQELCAKFSEIEQVQSPFSV 248 G T A V + +Q+G + N LK IDL + EL K +I + V Sbjct: 88 GTTTATVLGQAIVQEGAKAVAAGMNPMDLKRGIDLAVNEVVAELLKKAKKINTSEEVAQV 147 Query: 247 ISVSAENERVLR---GEQVKRIRNDSLVHPRSIYKTMDELWDGEI*LKISAGI 98 ++SA E + E ++++ N+ ++ T++E E L++ G+ Sbjct: 148 GTISANGEAEIGKMIAEAMQKVGNEGVI-------TVEEAKTAETELEVVEGM 193
>DGKD_HUMAN (Q16760) Diacylglycerol kinase delta (EC 2.7.1.107) (Diglyceride| kinase delta) (DGK-delta) (DAG kinase delta) (130 kDa diacylglycerol kinase) Length = 1214 Score = 30.0 bits (66), Expect = 4.4 Identities = 23/95 (24%), Positives = 43/95 (45%) Frame = -1 Query: 487 LGRMKVVADNPVVTSIAESLGRTPAQVALRWGIQQGQSVLPKSANESRLKENIDLFGWSI 308 LG D+ + I E L R ++ RW + ++ LP+ A+ S + E+ Sbjct: 416 LGWGSACDDDTQLPQILEKLERASTKMLDRWSVMAYEAKLPRQASSSTVTEDF------- 468 Query: 307 PQELCAKFSEIEQVQSPFSVISVSAENERVLRGEQ 203 ++ SE++Q+ F SV+A ++L +Q Sbjct: 469 -----SEDSEVQQIL--FYEDSVAAHLSKILTSDQ 496
>YAJO_ECOLI (P77735) Hypothetical oxidoreductase yajO (EC 1.-.-.-)| Length = 324 Score = 30.0 bits (66), Expect = 4.4 Identities = 20/71 (28%), Positives = 36/71 (50%), Gaps = 2/71 (2%) Frame = -1 Query: 451 VTSIAESLGRTPAQVALRWGIQQGQSVLP--KSANESRLKENIDLFGWSIPQELCAKFSE 278 +T ++E LG T AQVAL W + + P ++ E +L E ++ ++ E + +E Sbjct: 254 LTGVSEELGATRAQVALAWLLSKPGIAAPIIGTSREEQLDELLNAVDITLKPE---QIAE 310 Query: 277 IEQVQSPFSVI 245 +E P V+ Sbjct: 311 LETPYKPHPVV 321
>PUR7_RHIME (Q92PI3) Phosphoribosylaminoimidazole-succinocarboxamide synthase| (EC 6.3.2.6) (SAICAR synthetase) Length = 254 Score = 30.0 bits (66), Expect = 4.4 Identities = 20/49 (40%), Positives = 27/49 (55%), Gaps = 11/49 (22%) Frame = -1 Query: 409 VALRWGIQQGQSVLPKSANESRLK-----------ENIDLFGWSIPQEL 296 +A R GI++G +VLP+S E K E+I FGW+ PQEL Sbjct: 101 LAKRLGIEEG-TVLPRSIIEFYYKADALDDPMVSEEHITAFGWASPQEL 148
>MORA_RABIT (P82810) Morphine 6-dehydrogenase (EC 1.1.1.218) (Fragments)| Length = 125 Score = 29.6 bits (65), Expect = 5.7 Identities = 21/73 (28%), Positives = 35/73 (47%) Frame = -1 Query: 517 NXVHFSAYAPLGRMKVVADNPVVTSIAESLGRTPAQVALRWGIQQGQSVLPKSANESRLK 338 N V Y + V+ + S + ++PA +ALR+ +Q+G VL KS E +K Sbjct: 54 NQVEXHPYLNQSKDIVLVAYSALGSSRDPWKQSPALIALRYQLQRGVVVLAKSFIEREIK 113 Query: 337 ENIDLFGWSIPQE 299 +FG+ + E Sbjct: 114 ----VFGFQLSSE 122
>YAKC_SCHPO (Q09923) Aldo-keto reductase yakc [NADP+] (EC 1.1.1.-)| Length = 340 Score = 28.9 bits (63), Expect = 9.7 Identities = 23/84 (27%), Positives = 30/84 (35%), Gaps = 30/84 (35%) Frame = -1 Query: 526 CRTNXVHFSAYAPLGR------MKVVADNPV------------------------VTSIA 437 CR N + YAPLGR K D P + IA Sbjct: 197 CRENNITIVCYAPLGRGFLTGAYKSPDDFPEGDFRRKAPRYQKENFYKNLELVTKIEKIA 256 Query: 436 ESLGRTPAQVALRWGIQQGQSVLP 365 + TP Q++L W + QG +LP Sbjct: 257 TANNITPGQLSLAWLLAQGDDILP 280
>MECP2_RAT (Q00566) Methyl-CpG-binding protein 2 (MeCP-2 protein) (MeCP2)| Length = 492 Score = 28.9 bits (63), Expect = 9.7 Identities = 19/55 (34%), Positives = 24/55 (43%) Frame = +1 Query: 316 SQTGQCSPSTSTHSHF*EARSDPAGCPIVERPVPAFSPSSRLSMSPPGYPRRLSS 480 S + P H H A S A P++ P P SS +SPP P+ LSS Sbjct: 355 SSSASSPPKKEHHHHHHHAESPKAPMPLLPPPPPPEPQSSEDPISPP-EPQDLSS 408
>ATX2_HUMAN (Q99700) Ataxin-2 (Spinocerebellar ataxia type 2 protein)| (Trinucleotide repeat-containing gene 13 protein) Length = 1312 Score = 28.9 bits (63), Expect = 9.7 Identities = 29/114 (25%), Positives = 49/114 (42%) Frame = -1 Query: 478 MKVVADNPVVTSIAESLGRTPAQVALRWGIQQGQSVLPKSANESRLKENIDLFGWSIPQE 299 M + A +P S A + TP+ A +Q + P KENI P E Sbjct: 721 MPIPAASPTPASPASNRAVTPSSEAKDSRLQDQRQNSPAGN-----KENIK------PNE 769 Query: 298 LCAKFSEIEQVQSPFSVISVSAENERVLRGEQVKRIRNDSLVHPRSIYKTMDEL 137 FS+ E + V +E+ + + + +K+ +ND + P S ++MD+L Sbjct: 770 TSPSFSKAENK----GISPVVSEHRKQI--DDLKKFKNDFRLQPSSTSESMDQL 817
>TMC8_MOUSE (Q7TN58) Transmembrane channel-like protein 8 (Epidermodysplasia| verruciformis protein 2 homolog) Length = 722 Score = 28.9 bits (63), Expect = 9.7 Identities = 24/68 (35%), Positives = 31/68 (45%), Gaps = 4/68 (5%) Frame = +1 Query: 274 QFQKTWHTVLEE*TSQTGQCSPST-STHSHF*EARSDPAGCPIVERP---VPAFSPSSRL 441 Q Q+ WH V ++ + + SP S HS RS G P P P +PS+RL Sbjct: 639 QVQEKWHLV-DDLSRLLPELSPEPGSPHSRASRPRSFCPGFPCPGSPGPRTPRLAPSNRL 697 Query: 442 SMSPPGYP 465 S S G P Sbjct: 698 SSSSLGAP 705
>FTSZ_NEIMB (P0A0S6) Cell division protein ftsZ| Length = 392 Score = 28.9 bits (63), Expect = 9.7 Identities = 17/44 (38%), Positives = 23/44 (52%) Frame = -1 Query: 457 PVVTSIAESLGRTPAQVALRWGIQQGQSVLPKSANESRLKENID 326 PVV IA+SLG V R +G+ V A +LKE++D Sbjct: 118 PVVAEIAKSLGILTVAVVTRPFAYEGKRVHVAQAGLEQLKEHVD 161
>FTSZ_NEIMA (P0A0S5) Cell division protein ftsZ| Length = 392 Score = 28.9 bits (63), Expect = 9.7 Identities = 17/44 (38%), Positives = 23/44 (52%) Frame = -1 Query: 457 PVVTSIAESLGRTPAQVALRWGIQQGQSVLPKSANESRLKENID 326 PVV IA+SLG V R +G+ V A +LKE++D Sbjct: 118 PVVAEIAKSLGILTVAVVTRPFAYEGKRVHVAQAGLEQLKEHVD 161 Database: uniprot_sprot.fasta Posted date: May 25, 2006 5:36 PM Number of letters in database: 80,573,946 Number of sequences in database: 219,361 Lambda K H 0.318 0.135 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 76,828,674 Number of Sequences: 219361 Number of extensions: 1561034 Number of successful extensions: 4438 Number of sequences better than 10.0: 98 Number of HSP's better than 10.0 without gapping: 4230 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 4399 length of database: 80,573,946 effective HSP length: 105 effective length of database: 57,541,041 effective search space used: 4315578075 frameshift window, decay const: 50, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
