>SOS_DROME (P26675) Protein son of sevenless|
          Length = 1596

 Score = 34.3 bits (77), Expect = 0.39
 Identities = 32/112 (28%), Positives = 48/112 (42%), Gaps = 8/112 (7%)
 Frame = +3

Query: 375  SSSTTKPLKYSKSVRSKNL-------TMMQYIHSPDISYSLVLTLHFHTYEYHHQNQFQY 533
            SS+TT PL  + S  S N+       T   Y H   +        H   Y  HHQ+   +
Sbjct: 1474 SSTTTSPLTPAMSPMSPNIPSHPVESTSSSYAHQLRMRQQQQQQTHPAIYSQHHQHHATH 1533

Query: 534  LGHHQNQRCHFPVLSNP-RNRPIDKVL*PCRKNRHCSPENLSRRIALSSSLY 686
            L HH +Q       SNP ++R   K   P   +   +P+ L  + +LS++ Y
Sbjct: 1534 LPHHPHQH-----HSNPTQSRSSPKEFFPIATSLEGTPK-LPPKPSLSANFY 1579

>AXN_XENLA (Q9YGY0) Axin (Axis inhibition protein) (xAxin)|
          Length = 842

 Score = 33.1 bits (74), Expect = 0.86
 Identities = 30/107 (28%), Positives = 39/107 (36%), Gaps = 4/107 (3%)
 Frame = +3

Query: 207 FGFRCSDCNCVPSEFRCSDCNELLPEYCLQSTLQTIRAEPQFIFPLYKQKPPLGDFSSST 386
           F  R S+  CV  + R  D +E  PE  L   +Q +   P        Q P  G  S  +
Sbjct: 447 FNSRYSETGCVGMQIR--DAHEENPESILDEHVQRVMKTPGC------QSPGTGRHSPKS 498

Query: 387 TKPLKYSKSVRSKNLTMMQYIHSPDISYSLVLT----LHFHTYEYHH 515
             P  +       +L  MQ  H    S S        LH H + YHH
Sbjct: 499 RSPDGHLSKTLPGSLGTMQTGHGKHSSKSTAKVDSGNLHHHKHVYHH 545

>DISC_DROME (P23792) Protein disconnected|
          Length = 568

 Score = 31.2 bits (69), Expect = 3.3
 Identities = 25/92 (27%), Positives = 36/92 (39%), Gaps = 7/92 (7%)
 Frame = +3

Query: 309 TIRAEPQFIFP------LYKQKPPLGDFSSSTTKPLKYSKSVRSKNLTMMQYIHSPDISY 470
           T +A P    P      L K  PP+    S   +    S  +++++    QY H   +  
Sbjct: 459 TSQAPPTAFLPAGSPVDLAKDSPPMWSLLSEMYR----SMLLKTQH---QQYNHHHQLQQ 511

Query: 471 SLVLTLHFH-TYEYHHQNQFQYLGHHQNQRCH 563
                 H H T  +HHQ Q  +LGHH     H
Sbjct: 512 QHQQEQHHHLTLSHHHQEQHHHLGHHHMGHHH 543

>ADA21_HUMAN (Q9UKJ8) ADAM 21 precursor (EC 3.4.24.-) (A disintegrin and|
           metalloproteinase domain 21)
          Length = 722

 Score = 31.2 bits (69), Expect = 3.3
 Identities = 15/32 (46%), Positives = 19/32 (59%), Gaps = 2/32 (6%)
 Frame = +3

Query: 201 CSFGFRCSDCNCVPSEFRC-SDCNEL-LPEYC 290
           C+FG  C DC  +PS   C  + NE  LPE+C
Sbjct: 446 CAFGLCCKDCKFMPSGELCRQEVNECDLPEWC 477

>BRC1_DROME (Q01295) Broad-complex core-protein isoforms 1/2/3/4/5|
          Length = 727

 Score = 31.2 bits (69), Expect = 3.3
 Identities = 27/106 (25%), Positives = 44/106 (41%), Gaps = 4/106 (3%)
 Frame = +3

Query: 246 EFRCSDCNELLPEYC-LQSTLQTIRAEPQFIFPLYKQKPPLGDFSS---STTKPLKYSKS 413
           +FRC+ CN+ L     L+  +Q +   P         K P+ +      S+   L+  KS
Sbjct: 635 DFRCNPCNKNLSSLTRLKRHIQNVHMRPT--------KEPVCNICKRVYSSLNSLRNHKS 686

Query: 414 VRSKNLTMMQYIHSPDISYSLVLTLHFHTYEYHHQNQFQYLGHHQN 551
           +  +NL   +    P +  +      F    YH Q+Q Q L HH +
Sbjct: 687 IYHRNLKQPK--QEPGVGATQAAANSF----YHQQHQQQQLNHHSS 726

>TYSY_BPT4 (P00471) Thymidylate synthase (EC 2.1.1.45) (TS) (TSase)|
          Length = 286

 Score = 31.2 bits (69), Expect = 3.3
 Identities = 20/79 (25%), Positives = 34/79 (43%)
 Frame = +3

Query: 228 CNCVPSEFRCSDCNELLPEYCLQSTLQTIRAEPQFIFPLYKQKPPLGDFSSSTTKPLKYS 407
           CN +P +   S  N  +    ++   + +R EP+ +  L     P      ST + LKY 
Sbjct: 202 CNLIPGDLIFSGGNTHIYMNHVEQCKEILRREPKELCELVISGLPYKFRYLSTKEQLKYV 261

Query: 408 KSVRSKNLTMMQYIHSPDI 464
             +R K+  +  Y+  P I
Sbjct: 262 LKLRPKDFVLNNYVSHPPI 280

>PTPRR_MOUSE (Q62132) Receptor-type tyrosine-protein phosphatase R precursor (EC|
           3.1.3.48) (Protein-tyrosine-phosphatase SL)
           (Phosphotyrosine phosphatase 13)
          Length = 656

 Score = 31.2 bits (69), Expect = 3.3
 Identities = 15/42 (35%), Positives = 20/42 (47%)
 Frame = +3

Query: 444 YIHSPDISYSLVLTLHFHTYEYHHQNQFQYLGHHQNQRCHFP 569
           Y HS DI  SL +    + + YH  ++ Q   HHQ     FP
Sbjct: 44  YDHSQDIKKSLDIAQEAYKHNYHSPSEVQISKHHQIINSAFP 85

>ADA29_HUMAN (Q9UKF5) ADAM 29 precursor (A disintegrin and metalloproteinase|
           domain 29)
          Length = 820

 Score = 30.8 bits (68), Expect = 4.3
 Identities = 15/32 (46%), Positives = 19/32 (59%), Gaps = 2/32 (6%)
 Frame = +3

Query: 201 CSFGFRCSDCNCVPSEFRC-SDCNEL-LPEYC 290
           C+FG  C DC  +PS   C  + NE  LPE+C
Sbjct: 437 CAFGLCCKDCKFLPSGKVCRKEVNECDLPEWC 468

>ADA20_HUMAN (O43506) ADAM 20 precursor (EC 3.4.24.-) (A disintegrin and|
           metalloproteinase domain 20)
          Length = 726

 Score = 30.4 bits (67), Expect = 5.6
 Identities = 14/34 (41%), Positives = 19/34 (55%), Gaps = 4/34 (11%)
 Frame = +3

Query: 201 CSFGFRCSDCNCVPSEFRC----SDCNELLPEYC 290
           C+FG  C DC  +PS   C     +C+  LPE+C
Sbjct: 447 CAFGICCKDCKFLPSGTLCRQQVGECD--LPEWC 478

>Y875_RICPR (Q9ZC92) Hypothetical protein RP875|
          Length = 174

 Score = 30.4 bits (67), Expect = 5.6
 Identities = 15/28 (53%), Positives = 19/28 (67%), Gaps = 4/28 (14%)
 Frame = -3

Query: 294 EDNIQEVIH----YNLNIGTRKEHNYNL 223
           EDNI+E I+    YNL + T  EHNYN+
Sbjct: 101 EDNIKEAINFIVTYNLTLITLVEHNYNI 128

>ADA22_XENLA (O42596) ADAM 22 precursor (A disintegrin and metalloproteinase|
           domain 22) (Metalloprotease-disintegrin MDC11b)
           (MDC11.2)
          Length = 935

 Score = 30.0 bits (66), Expect = 7.3
 Identities = 16/40 (40%), Positives = 21/40 (52%), Gaps = 4/40 (10%)
 Frame = +3

Query: 201 CSFGFRCSDCNCVPSEFRC----SDCNELLPEYCLQSTLQ 308
           CS G  CS+C   P E  C    +DC+  +PE C  +T Q
Sbjct: 487 CSDGLCCSNCKFNPKEMLCREAVNDCD--IPETCTGNTSQ 524

>NR4A3_RAT (P51179) Orphan nuclear receptor NR4A3 (Nuclear hormone receptor|
           NOR-1/NOR-2) (Neuron-derived orphan receptor 1/2)
          Length = 628

 Score = 30.0 bits (66), Expect = 7.3
 Identities = 14/39 (35%), Positives = 20/39 (51%)
 Frame = +3

Query: 495 HTYEYHHQNQFQYLGHHQNQRCHFPVLSNPRNRPIDKVL 611
           H Y +HH +   +  HHQ Q+   P    P + P D+VL
Sbjct: 96  HGYHHHHHHHHHHHHHHQQQQPSIP----PPSGPEDEVL 130

>NFYB6_ARATH (Q84W66) Nuclear transcription factor Y subunit B-6 (AtNF-YB-6)|
           (Protein LEAFY COTYLEDON 1-LIKE)
          Length = 234

 Score = 29.6 bits (65), Expect = 9.5
 Identities = 16/48 (33%), Positives = 23/48 (47%)
 Frame = +3

Query: 414 VRSKNLTMMQYIHSPDISYSLVLTLHFHTYEYHHQNQFQYLGHHQNQR 557
           V+  N TM +Y      +Y  V  +H   Y Y HQN F + G+  N +
Sbjct: 169 VKRPNGTMTEYG-----AYGPVPGIHMAQYHYRHQNGFVFSGNEPNSK 211

>PSD_MANSM (Q65RD9) Phosphatidylserine decarboxylase proenzyme (EC 4.1.1.65)|
           [Contains: Phosphatidylserine decarboxylase alpha chain;
           Phosphatidylserine decarboxylase beta chain]
          Length = 301

 Score = 29.6 bits (65), Expect = 9.5
 Identities = 23/97 (23%), Positives = 46/97 (47%), Gaps = 5/97 (5%)
 Frame = +3

Query: 222 SDCNCVPSEFRCSDCNELLPEYCLQS-----TLQTIRAEPQFIFPLYKQKPPLGDFSSST 386
           +D  C+P++ + S C  +  E  LQ+     +L+ + A  + +  L+K     G+F ++ 
Sbjct: 99  TDALCLPADGKISQCGHIDDELLLQAKGHSFSLRDLLAGDEELTRLFKD----GEFVTTY 154

Query: 387 TKPLKYSKSVRSKNLTMMQYIHSPDISYSLVLTLHFH 497
             P  Y +     N T+ + I+ P   +S+   L+ H
Sbjct: 155 LSPRDYHRVHMPCNGTIRKMIYVPGELFSVNPFLNTH 191

>LRP1B_MOUSE (Q9JI18) Low-density lipoprotein receptor-related protein 1B|
            precursor (Low-density lipoprotein receptor-related
            protein-deleted in tumor) (LRP-DIT)
          Length = 4599

 Score = 29.6 bits (65), Expect = 9.5
 Identities = 14/37 (37%), Positives = 21/37 (56%), Gaps = 4/37 (10%)
 Frame = +3

Query: 186  CRL*LCS-FGFRCSDCNCVPSEFRCS---DCNELLPE 284
            C++  CS   FRC+D  C+P   RC+   DC++   E
Sbjct: 2586 CKVSTCSTVEFRCADGTCIPRSARCNQNMDCSDASDE 2622

>SYE_ACIAD (Q6F7C8) Glutamyl-tRNA synthetase (EC 6.1.1.17) (Glutamate--tRNA|
           ligase) (GluRS)
          Length = 502

 Score = 29.6 bits (65), Expect = 9.5
 Identities = 12/31 (38%), Positives = 15/31 (48%)
 Frame = +3

Query: 513 HQNQFQYLGHHQNQRCHFPVLSNPRNRPIDK 605
           HQ  +QY G      CH P+L NP    + K
Sbjct: 223 HQLLYQYFGWDMPTLCHMPLLRNPDKSKLSK 253

>LRP2_RAT (P98158) Low-density lipoprotein receptor-related protein 2 precursor|
            (Megalin) (Glycoprotein 330) (gp330)
          Length = 4660

 Score = 26.9 bits (58), Expect(2) = 9.6
 Identities = 9/20 (45%), Positives = 13/20 (65%)
 Frame = +3

Query: 213  FRCSDCNCVPSEFRCSDCNE 272
            FRC+D  C+PS + C   N+
Sbjct: 3766 FRCADQQCIPSRWVCDQEND 3785



 Score = 20.8 bits (42), Expect(2) = 9.6
 Identities = 6/10 (60%), Positives = 9/10 (90%)
 Frame = +1

Query: 178  FRCADCNCVP 207
            FRCA+ +C+P
Sbjct: 3727 FRCANHHCIP 3736


  Database: uniprot_sprot.fasta
    Posted date:  May 25, 2006  5:36 PM
  Number of letters in database: 80,573,946
  Number of sequences in database:  219,361
  
Lambda     K      H
   0.318    0.135    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 98,039,763
Number of Sequences: 219361
Number of extensions: 2041950
Number of successful extensions: 5716
Number of sequences better than 10.0: 17
Number of HSP's better than 10.0 without gapping: 5021
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5660
length of database: 80,573,946
effective HSP length: 109
effective length of database: 56,663,597
effective search space used: 7196276819
frameshift window, decay const: 50,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)