>MTHR_ORYSA (Q75HE6) Probable methylenetetrahydrofolate reductase (EC 1.5.1.20)|
          Length = 594

 Score =  305 bits (782), Expect = 5e-83
 Identities = 144/164 (87%), Positives = 157/164 (95%)
 Frame = -3

Query: 589 MNSKGFLTINSQPAVNAEKSESPSVGWGGPGXYVYQKAYVEFFCAKEKLDQLIEKSKAFP 410
           +N KGFLTINSQPAVN E+S+S SVGWGGPG YVYQKAY+EFFC+KEKLDQLIEKSKAFP
Sbjct: 431 INQKGFLTINSQPAVNGERSDSTSVGWGGPGGYVYQKAYLEFFCSKEKLDQLIEKSKAFP 490

Query: 409 SLTYIAVNKEGESISNIPANAVNAVTWGVFPGKEIIQPTVVDSASFMVWKDEAFEIWSRG 230
           SLTYIAVNK+GES SNIP NAVNAVTWGVFPGKEI+QPTVVDSASFMVWKDEAFEIWS+G
Sbjct: 491 SLTYIAVNKDGESFSNIPTNAVNAVTWGVFPGKEIVQPTVVDSASFMVWKDEAFEIWSKG 550

Query: 229 WACLFPEGDSSRELLEQVQKTYCLVSLVDNDYISGDLFAAFKEI 98
           WACLFPEGDSSRE+L++VQK+Y LVSLVDNDYI+GDLFAAFKEI
Sbjct: 551 WACLFPEGDSSREILDKVQKSYFLVSLVDNDYINGDLFAAFKEI 594

>MTHR1_MAIZE (Q9SE94) Methylenetetrahydrofolate reductase 1 (EC 1.5.1.20)|
           (ZmMTHFR1)
          Length = 593

 Score =  298 bits (763), Expect = 8e-81
 Identities = 141/162 (87%), Positives = 151/162 (93%)
 Frame = -3

Query: 589 MNSKGFLTINSQPAVNAEKSESPSVGWGGPGXYVYQKAYVEFFCAKEKLDQLIEKSKAFP 410
           +N KGFLTINSQPAVN EKS+SP+VGWGGPG YVYQKAY+EFFCAKEKLDQLIEK KAFP
Sbjct: 431 INQKGFLTINSQPAVNGEKSDSPTVGWGGPGGYVYQKAYLEFFCAKEKLDQLIEKIKAFP 490

Query: 409 SLTYIAVNKEGESISNIPANAVNAVTWGVFPGKEIIQPTVVDSASFMVWKDEAFEIWSRG 230
           SLTYIAVNK+GE+ SNI  NAVNAVTWGVFPGKEIIQPTVVD ASFMVWKDEAFEIW+RG
Sbjct: 491 SLTYIAVNKDGETFSNISPNAVNAVTWGVFPGKEIIQPTVVDHASFMVWKDEAFEIWTRG 550

Query: 229 WACLFPEGDSSRELLEQVQKTYCLVSLVDNDYISGDLFAAFK 104
           W C+FPEGDSSRELLE+VQKTY LVSLVDNDY+ GDLFAAFK
Sbjct: 551 WGCMFPEGDSSRELLEKVQKTYYLVSLVDNDYVQGDLFAAFK 592

>MTHR1_ARATH (Q9SE60) Methylenetetrahydrofolate reductase 1 (EC 1.5.1.20)|
           (AtMTHFR1)
          Length = 592

 Score =  251 bits (640), Expect = 1e-66
 Identities = 115/161 (71%), Positives = 139/161 (86%)
 Frame = -3

Query: 589 MNSKGFLTINSQPAVNAEKSESPSVGWGGPGXYVYQKAYVEFFCAKEKLDQLIEKSKAFP 410
           +NS GFLTINSQP+VNA KS+SP++GWGGPG YVYQKAY+EFFC+K+KLD L+EKSKAFP
Sbjct: 431 INSNGFLTINSQPSVNAAKSDSPAIGWGGPGGYVYQKAYLEFFCSKDKLDTLVEKSKAFP 490

Query: 409 SLTYIAVNKEGESISNIPANAVNAVTWGVFPGKEIIQPTVVDSASFMVWKDEAFEIWSRG 230
           S+TY+AVNK    +SN   + VNAVTWGVFP KE+IQPT+VD ASF VWKDEAFEIWSR 
Sbjct: 491 SITYMAVNKSENWVSNTGESDVNAVTWGVFPAKEVIQPTIVDPASFKVWKDEAFEIWSRS 550

Query: 229 WACLFPEGDSSRELLEQVQKTYCLVSLVDNDYISGDLFAAF 107
           WA L+PE D SR+LLE+V+ +Y LVSLVDN+YI+GD+F+ F
Sbjct: 551 WANLYPEDDPSRKLLEEVKNSYYLVSLVDNNYINGDIFSVF 591

>MTHR2_ARATH (O80585) Methylenetetrahydrofolate reductase 2 (EC 1.5.1.20)|
           (AtMTHFR2)
          Length = 594

 Score =  246 bits (629), Expect = 3e-65
 Identities = 115/164 (70%), Positives = 138/164 (84%)
 Frame = -3

Query: 589 MNSKGFLTINSQPAVNAEKSESPSVGWGGPGXYVYQKAYVEFFCAKEKLDQLIEKSKAFP 410
           +NSKGFLTINSQP+VNAE+S+SP+VGWGGP  YVYQKAY+EFFC+KEKLD ++EK KA P
Sbjct: 431 VNSKGFLTINSQPSVNAERSDSPTVGWGGPVGYVYQKAYLEFFCSKEKLDAVVEKCKALP 490

Query: 409 SLTYIAVNKEGESISNIPANAVNAVTWGVFPGKEIIQPTVVDSASFMVWKDEAFEIWSRG 230
           S+TY+AVNK  + +SN     VNAVTWGVFP KEIIQPT+VD ASF VWKDEAFE WSR 
Sbjct: 491 SITYMAVNKGEQWVSNTAQADVNAVTWGVFPAKEIIQPTIVDPASFNVWKDEAFETWSRS 550

Query: 229 WACLFPEGDSSRELLEQVQKTYCLVSLVDNDYISGDLFAAFKEI 98
           WA L+PE D SR LLE+V+ +Y LVSLV+NDYI+GD+FA F ++
Sbjct: 551 WANLYPEADPSRNLLEEVKNSYYLVSLVENDYINGDIFAVFADL 594

>MTHR_HUMAN (P42898) Methylenetetrahydrofolate reductase (EC 1.5.1.20)|
          Length = 656

 Score =  166 bits (420), Expect = 5e-41
 Identities = 78/153 (50%), Positives = 104/153 (67%), Gaps = 1/153 (0%)
 Frame = -3

Query: 589 MNSKGFLTINSQPAVNAEKSESPSVGWGGPGXYVYQKAYVEFFCAKEKLDQLIEKSKAFP 410
           +N +G LTINSQP +N + S  P VGWG  G YV+QKAY+EFF ++E  + L++  K + 
Sbjct: 474 VNRQGILTINSQPNINGKPSSDPIVGWGPSGGYVFQKAYLEFFTSRETAEALLQVLKKYE 533

Query: 409 -SLTYIAVNKEGESISNIPANAVNAVTWGVFPGKEIIQPTVVDSASFMVWKDEAFEIWSR 233
             + Y  VN +GE+I+N P    NAVTWG+FPG+EIIQPTVVD  SFM WKDEAF +W  
Sbjct: 534 LRVNYHLVNVKGENITNAPELQPNAVTWGIFPGREIIQPTVVDPVSFMFWKDEAFALWIE 593

Query: 232 GWACLFPEGDSSRELLEQVQKTYCLVSLVDNDY 134
            W  L+ E   SR +++ +   Y LV+LVDND+
Sbjct: 594 RWGKLYEEESPSRTIIQYIHDNYFLVNLVDNDF 626

>MTHR_MACFA (Q60HE5) Methylenetetrahydrofolate reductase (EC 1.5.1.20)|
          Length = 656

 Score =  166 bits (419), Expect = 6e-41
 Identities = 78/153 (50%), Positives = 104/153 (67%), Gaps = 1/153 (0%)
 Frame = -3

Query: 589 MNSKGFLTINSQPAVNAEKSESPSVGWGGPGXYVYQKAYVEFFCAKEKLDQLIEKSKAFP 410
           +N +G LTINSQP +N + S  P VGWG  G YV+QKAY+EFF ++E  + L++  K + 
Sbjct: 474 VNRQGILTINSQPNINGKPSSDPVVGWGPSGGYVFQKAYLEFFTSRETAEALLQVLKKYE 533

Query: 409 -SLTYIAVNKEGESISNIPANAVNAVTWGVFPGKEIIQPTVVDSASFMVWKDEAFEIWSR 233
             + Y  VN +GE+I+N P    NAVTWG+FPG+EIIQPTVVD  SFM WKDEAF +W  
Sbjct: 534 LRVNYHLVNVKGENITNAPELQPNAVTWGIFPGREIIQPTVVDPISFMFWKDEAFALWIE 593

Query: 232 GWACLFPEGDSSRELLEQVQKTYCLVSLVDNDY 134
            W  L+ E   SR +++ +   Y LV+LVDND+
Sbjct: 594 QWGKLYEEESPSRTIIQYIHDNYFLVNLVDNDF 626

>MTHR_MOUSE (Q9WU20) Methylenetetrahydrofolate reductase (EC 1.5.1.20)|
          Length = 654

 Score =  163 bits (413), Expect = 3e-40
 Identities = 77/153 (50%), Positives = 105/153 (68%), Gaps = 1/153 (0%)
 Frame = -3

Query: 589 MNSKGFLTINSQPAVNAEKSESPSVGWGGPGXYVYQKAYVEFFCAKEKLDQLIEKSKAFP 410
           +N  G LTINSQP +NA+ S  P VGWG  G YV+QKAY+EFF ++E ++ L++  K + 
Sbjct: 473 VNRLGILTINSQPNINAKPSSDPVVGWGPSGGYVFQKAYLEFFTSRETVEALLQVLKTYE 532

Query: 409 -SLTYIAVNKEGESISNIPANAVNAVTWGVFPGKEIIQPTVVDSASFMVWKDEAFEIWSR 233
             + Y  V+ +GE+I+N P    NAVTWG+FPG+EIIQPTVVD  SFM WKDEAF +W  
Sbjct: 533 LRVNYHIVDVKGENITNAPELQPNAVTWGIFPGREIIQPTVVDPISFMFWKDEAFALWIE 592

Query: 232 GWACLFPEGDSSRELLEQVQKTYCLVSLVDNDY 134
            W  L+ E   SR +++ +   Y LV+LVDN++
Sbjct: 593 QWGKLYEEESPSRMIIQYIHDNYFLVNLVDNEF 625

>MTHR1_SCHPO (Q10258) Methylenetetrahydrofolate reductase 1 (EC 1.5.1.20)|
          Length = 603

 Score =  153 bits (386), Expect = 4e-37
 Identities = 79/165 (47%), Positives = 102/165 (61%), Gaps = 1/165 (0%)
 Frame = -3

Query: 589 MNSKGFLTINSQPAVNAEKSESPSVGWGGPGXYVYQKAYVEFFCAKEKLDQLIEKSKAFP 410
           MN   FLTINSQPA+N EKS  P  GWG P  YV+QK YVEFF     L++L E  K   
Sbjct: 424 MNRNAFLTINSQPALNGEKSSHPVFGWGPPNGYVFQKPYVEFFVHPSLLNELKETVKKLN 483

Query: 409 SLTYIAVNKEGESISNIPANAVNAVTWGVFPGKEIIQPTVVDSASFMVWKDEAFEIWSRG 230
           S++Y   NK G+  +N      NAVTWGVFP +EIIQPT+V+S SF+ WKDEA+ +    
Sbjct: 484 SVSYFVTNKNGDLDTNSQYEIPNAVTWGVFPNREIIQPTIVESTSFLAWKDEAYSL-GME 542

Query: 229 WACLFPEGDSSRELLEQVQKTYCLVSLVDNDYISG-DLFAAFKEI 98
           WA  +     SR+LL  + K + L  +VDND+ +G  LF  F ++
Sbjct: 543 WANAYSPDSISRKLLVSMMKEWFLCVIVDNDFQNGQSLFDVFNKM 587

>MTHR2_YEAST (P53128) Methylenetetrahydrofolate reductase 2 (EC 1.5.1.20)|
          Length = 599

 Score =  141 bits (355), Expect = 2e-33
 Identities = 72/159 (45%), Positives = 100/159 (62%), Gaps = 3/159 (1%)
 Frame = -3

Query: 589 MNSKGFLTINSQPAVNAEKSESPSVGWGGPGXYVYQKAYVEFFCAKEKLDQLIEKSKAFP 410
           +N    +TINSQP VN  +S     GWG    YVYQK Y+EF   K KL +LI+  K   
Sbjct: 432 LNQHSIITINSQPQVNGIRSNDKIHGWGPKDGYVYQKQYLEFMLPKTKLPKLIDTLKNNE 491

Query: 409 SLTYIAVNKEGESISNIPANA-VNAVTWGVFPGKEIIQPTVVDSASFMVWKDEAFEIWSR 233
            LTY A++ +G+ +SN P N+  NAVTWG+FPG+EI+QPT+V+  SF+ WK+E + I + 
Sbjct: 492 FLTYFAIDSQGDLLSNHPDNSKSNAVTWGIFPGREILQPTIVEKISFLAWKEEFYHILNE 551

Query: 232 GWACLFPEGDS--SRELLEQVQKTYCLVSLVDNDYISGD 122
            W     + D   S + ++ +   YCLV++VDNDYIS D
Sbjct: 552 -WKLNMNKYDKPHSAQFIQSLIDDYCLVNIVDNDYISPD 589

>MTHR_CAEEL (Q17693) Probable methylenetetrahydrofolate reductase (EC 1.5.1.20)|
          Length = 663

 Score =  140 bits (353), Expect = 3e-33
 Identities = 72/154 (46%), Positives = 94/154 (61%), Gaps = 3/154 (1%)
 Frame = -3

Query: 586 NSKGFLTINSQPAVNAEKSESPSVGWGGPGXYVYQKAYVEFFCAKEKLDQLIEK-SKAFP 410
           N  G LT+NSQP+VN   S  P VGWG PG Y YQKAY+E F   E  D+LI+   + FP
Sbjct: 491 NENGILTVNSQPSVNGAPSTDPLVGWGKPGGYCYQKAYLECFMTAELSDKLIQIIEREFP 550

Query: 409 -SLTYIAVNKEGE-SISNIPANAVNAVTWGVFPGKEIIQPTVVDSASFMVWKDEAFEIWS 236
             + Y A+NK+     +N       AVTWGVFPG EI QPTVVD  SF  W+DEA+++W 
Sbjct: 551 VRVNYHAINKDSTFDKTNSEETTPIAVTWGVFPGSEIAQPTVVDPLSFRAWRDEAYQMWM 610

Query: 235 RGWACLFPEGDSSRELLEQVQKTYCLVSLVDNDY 134
             W   +P+   S  +++ V   + LV+LVDND+
Sbjct: 611 AQWGDFYPKESKSYGVIKAVHDEFRLVTLVDNDF 644

>MTHR2_SCHPO (O74927) Methylenetetrahydrofolate reductase 2 (EC 1.5.1.20)|
          Length = 641

 Score =  127 bits (319), Expect = 2e-29
 Identities = 62/153 (40%), Positives = 90/153 (58%)
 Frame = -3

Query: 589 MNSKGFLTINSQPAVNAEKSESPSVGWGGPGXYVYQKAYVEFFCAKEKLDQLIEKSKAFP 410
           +N   + T+ SQPAVN   S  P  GWG  G  V+QKA+VE F   + L   I K    P
Sbjct: 477 LNGNSWWTVGSQPAVNGAPSADPVFGWGPKGGRVFQKAFVECFVNGKDLKDFITKWHDNP 536

Query: 409 SLTYIAVNKEGESISNIPANAVNAVTWGVFPGKEIIQPTVVDSASFMVWKDEAFEIWSRG 230
            +TY A N + E ++N P +  +AVTWGV+PG+EIIQ T++   SF  W  E+F++W   
Sbjct: 537 QVTYYAGNNKSEFLTNAPKDGASAVTWGVYPGREIIQSTIIAEVSFKAWLSESFQVWGE- 595

Query: 229 WACLFPEGDSSRELLEQVQKTYCLVSLVDNDYI 131
           WA L+ +   SR+LLE       LV+++ +D++
Sbjct: 596 WANLYSKNTPSRKLLENCINDRWLVTVIHHDFM 628

>MTHR1_YEAST (P46151) Methylenetetrahydrofolate reductase 1 (EC 1.5.1.20)|
          Length = 657

 Score =  119 bits (298), Expect = 7e-27
 Identities = 61/159 (38%), Positives = 89/159 (55%), Gaps = 3/159 (1%)
 Frame = -3

Query: 589 MNSKGFLTINSQPAVNAEKSESPSVGWGGPGXYVYQKAYVEFFCAKEKLDQLIEKSKAF- 413
           +N +G+LT+ SQPA NA  S     GWG     +YQKA+VE F  +++ +  ++      
Sbjct: 490 LNYRGYLTLASQPATNATLSSDKIFGWGPAKGRLYQKAFVEMFIHRQQWETTLKPKLDHY 549

Query: 412 --PSLTYIAVNKEGESISNIPANAVNAVTWGVFPGKEIIQPTVVDSASFMVWKDEAFEIW 239
                +Y A +  G   +N+  ++ + VTWGVFP   + Q T+++  SF  W+DEAF IW
Sbjct: 550 GRRKFSYYAGDSSGSFETNLDPHSSSVVTWGVFPNSPVKQTTIIEEESFKAWRDEAFSIW 609

Query: 238 SRGWACLFPEGDSSRELLEQVQKTYCLVSLVDNDYISGD 122
           S  WA LFP    +  LL  V K YCLVS+V +D+   D
Sbjct: 610 SE-WAKLFPRNTPANILLRLVHKDYCLVSIVHHDFKETD 647

>PROS_RABIT (P98118) Vitamin K-dependent protein S precursor (Fragment)|
          Length = 646

 Score = 32.3 bits (72), Expect = 1.1
 Identities = 14/43 (32%), Positives = 22/43 (51%)
 Frame = -3

Query: 235 RGWACLFPEGDSSRELLEQVQKTYCLVSLVDNDYISGDLFAAF 107
           RGW  +       +E+++Q QK +CLV++    Y  G   A F
Sbjct: 422 RGWNLMKQGASGVKEIIQQKQKKHCLVTVEKGSYYPGSGIAQF 464

>YB1C_SCHPO (P87177) Hypothetical WD-repeat protein C3D6.12 in chromosome II|
          Length = 922

 Score = 30.8 bits (68), Expect = 3.1
 Identities = 21/62 (33%), Positives = 31/62 (50%)
 Frame = -3

Query: 304 IQPTVVDSASFMVWKDEAFEIWSRGWACLFPEGDSSRELLEQVQKTYCLVSLVDNDYISG 125
           + PT V S S     D +  +W +G   +F E +  REL EQ + T  LVS  +N    G
Sbjct: 668 VGPTFVVSGSH----DHSIRLWEQGDDLVFLEEERERELEEQYEST--LVSSYENAEADG 721

Query: 124 DL 119
           ++
Sbjct: 722 EV 723

>BUN2_DROME (Q24523) Protein bunched, class 2 isoform (Protein shortsighted)|
          Length = 1206

 Score = 30.4 bits (67), Expect = 4.0
 Identities = 22/63 (34%), Positives = 32/63 (50%), Gaps = 9/63 (14%)
 Frame = -3

Query: 379 GESISNIPANA----VNAVTWGVFPG----KEIIQPTVVDSASFMVWKDEAFEIWSRG-W 227
           G++I N+  N     +N V+  V PG    K+ I+ T   S  F V K E+ E + RG W
Sbjct: 466 GQTIQNVQVNVSDNIINVVSGAVTPGGTKKKDDIKETQHRSERFKVVKIESTEPFKRGRW 525

Query: 226 ACL 218
            C+
Sbjct: 526 MCM 528

>DXR_LEIXX (Q6AEY1) 1-deoxy-D-xylulose 5-phosphate reductoisomerase (EC|
           1.1.1.267) (DXP reductoisomerase)
           (1-deoxyxylulose-5-phosphate reductoisomerase)
           (2-C-methyl-D-erythritol 4-phosphate synthase)
          Length = 361

 Score = 30.0 bits (66), Expect = 5.3
 Identities = 11/24 (45%), Positives = 14/24 (58%)
 Frame = +1

Query: 181 ALATPWMSHPPGTGRPIPWTRSQT 252
           +L   W    PGTG P+ WTR+ T
Sbjct: 247 SLGLGWPDRVPGTGLPLDWTRAHT 270

>KLK10_RAT (P36375) Glandular kallikrein-10 precursor (EC 3.4.21.35) (Tissue|
           kallikrein) (T-kininogenase) (K10) (Proteinase B)
           (Endopeptidase K) [Contains: T-kininogenase light chain;
           T-kininogenase heavy chain] (Fragment)
          Length = 244

 Score = 29.3 bits (64), Expect = 9.0
 Identities = 15/41 (36%), Positives = 21/41 (51%)
 Frame = +2

Query: 233 PGPDLKRFIFPNHEARRVNDGRLDDLLAGEHAPSDSVHGVR 355
           P PD K F+  NH  +R +D   D +L     P+D   GV+
Sbjct: 80  PHPDYKPFLMRNHTRQRGDDYSNDLMLLHLSEPADITDGVK 120

>XYLA_STRLI (Q9RFM4) Xylose isomerase (EC 5.3.1.5)|
          Length = 395

 Score = 29.3 bits (64), Expect = 9.0
 Identities = 13/34 (38%), Positives = 19/34 (55%)
 Frame = -3

Query: 250 FEIWSRGWACLFPEGDSSRELLEQVQKTYCLVSL 149
           F +W+ GW  L P GD++RE L+  +    L  L
Sbjct: 13  FGLWTVGWQGLDPFGDATREALDPAESVRRLSQL 46


  Database: uniprot_sprot.fasta
    Posted date:  May 25, 2006  5:36 PM
  Number of letters in database: 80,573,946
  Number of sequences in database:  219,361
  
Lambda     K      H
   0.318    0.135    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 85,415,172
Number of Sequences: 219361
Number of extensions: 1835998
Number of successful extensions: 4863
Number of sequences better than 10.0: 18
Number of HSP's better than 10.0 without gapping: 4651
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4847
length of database: 80,573,946
effective HSP length: 106
effective length of database: 57,321,680
effective search space used: 5216272880
frameshift window, decay const: 50,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)