ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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| Clone Name | rbasd19i24 |
|---|---|
| Clone Library Name | barley_pub |
>PTP2_DICDI (P34138) Tyrosine-protein phosphatase 2 (EC 3.1.3.48)| (Protein-tyrosine-phosphate phosphohydrolase 2) (PTPA) Length = 377 Score = 99.8 bits (247), Expect = 8e-21 Identities = 53/160 (33%), Positives = 89/160 (55%), Gaps = 5/160 (3%) Frame = -1 Query: 723 NIKIVETRQDGELTLRSVKVQHKESDRVHTVLHIQHSTWPDHGVPNDSSTVRKILKRLYY 544 NI I + E TL ++K ++ + H Q++TWPDHG P ++ K + + + Sbjct: 216 NITIPDILIRREFTLENLK-----DNKTRKIYHFQYTTWPDHGTPVSTTGFLKFVSFVDH 270 Query: 543 VGKDHPIVAHCSAGIGRTGAYITIHNTVERIL-----RGDQAATNLVETVGKFRSQRPGI 379 + PIV HCSAGIGR+G ++ IH+ V + + + NL + V + R++RPG+ Sbjct: 271 EKRSGPIVVHCSAGIGRSGTFVAIHSIVAKFAKHYDEKKQAPSINLPKLVVEMRNERPGM 330 Query: 378 VQTEEQYKFCYHAIVDELKDLIRNSKH*SIFGGMKGVSYA 259 VQT +QY+FCY AI + + +++ + KG+SY+ Sbjct: 331 VQTRDQYRFCYLAISEAMNTVLKKEQK-----KRKGLSYS 365
>LAR_CAEEL (Q9BMN8) Tyrosine-protein phosphatase Lar-like precursor (EC| 3.1.3.48) (Protein-tyrosine phosphate 3) Length = 2200 Score = 91.3 bits (225), Expect = 3e-18 Identities = 50/134 (37%), Positives = 81/134 (60%), Gaps = 2/134 (1%) Frame = -1 Query: 726 LNIKIVETRQDGELTLRSVKVQHKESDRVHTVLHIQHSTWPDHGVPNDSSTVRKILKRLY 547 + + ++E+ T+R+++++ V + H+Q++ WPDHGVP+ + LKR+ Sbjct: 1770 IEVTLLESVHLAHYTMRTMRLKMVGEPEVREIKHLQYTAWPDHGVPDHPTPFLIFLKRVK 1829 Query: 546 YVGKDH--PIVAHCSAGIGRTGAYITIHNTVERILRGDQAATNLVETVGKFRSQRPGIVQ 373 + + PI++HCSAGIGRTGA+I I +ER LR D ++ V R+QR +VQ Sbjct: 1830 TLNPNDAGPIISHCSAGIGRTGAFIVIDCMLER-LRYDN-TVDIYGCVTALRAQRSYMVQ 1887 Query: 372 TEEQYKFCYHAIVD 331 TEEQY F + A++D Sbjct: 1888 TEEQYIFIHDAVLD 1901 Score = 55.1 bits (131), Expect = 2e-07 Identities = 33/123 (26%), Positives = 56/123 (45%), Gaps = 4/123 (3%) Frame = -1 Query: 681 LRSVKVQHKESDRVHTVLHIQHSTWPDHGVPNDSSTVRKILKRLYYV----GKDHPIVAH 514 LR ++ + V TV WPD G P+ + + +++ G PI H Sbjct: 2073 LREFRISDINTREVRTVRQFHFMEWPDVGKPHTADHFLDFVTQVHNTYAQFGCTGPITVH 2132 Query: 513 CSAGIGRTGAYITIHNTVERILRGDQAATNLVETVGKFRSQRPGIVQTEEQYKFCYHAIV 334 C +G GRT +I + ++R+ + ++ TV R++R ++Q EQY F Y A Sbjct: 2133 CCSGAGRTAVFIALSIILDRMRA--EHVVDVFTTVKLLRTERQNMIQEPEQYHFLYLAAY 2190 Query: 333 DEL 325 + L Sbjct: 2191 EYL 2193
>CSW_DROME (P29349) Tyrosine-protein phosphatase corkscrew (EC 3.1.3.48)| Length = 845 Score = 91.3 bits (225), Expect = 3e-18 Identities = 55/149 (36%), Positives = 75/149 (50%), Gaps = 9/149 (6%) Frame = -1 Query: 720 IKIVETRQDGELTLRSVKVQHKESDRVHTVLHIQHSTWPDHGVPNDSSTVRKILK----- 556 I+ V + TLR V ++ + H WPDHGVP D V L+ Sbjct: 507 IQCVSENSTSDYTLREFLVSWRDQP-ARRIFHYHFQVWPDHGVPADPGCVLNFLQDVNTR 565 Query: 555 --RLYYVG-KDHPIVAHCSAGIGRTGAYITIHNTVERILR-GDQAATNLVETVGKFRSQR 388 L G K PI HCSAGIGRTG +I I +++I+R G ++ T+ RSQR Sbjct: 566 QSHLAQAGEKPGPICVHCSAGIGRTGTFIVIDMILDQIVRNGLDTEIDIQRTIQMVRSQR 625 Query: 387 PGIVQTEEQYKFCYHAIVDELKDLIRNSK 301 G+VQTE QYKF Y+A+ ++ LI + Sbjct: 626 SGLVQTEAQYKFVYYAVQHYIQTLIARKR 654
>CSW_DROSI (Q8ISC9) Tyrosine-protein phosphatase corkscrew (EC 3.1.3.48)| (Fragment) Length = 555 Score = 91.3 bits (225), Expect = 3e-18 Identities = 55/149 (36%), Positives = 75/149 (50%), Gaps = 9/149 (6%) Frame = -1 Query: 720 IKIVETRQDGELTLRSVKVQHKESDRVHTVLHIQHSTWPDHGVPNDSSTVRKILK----- 556 I+ V + TLR V ++ + H WPDHGVP D V L+ Sbjct: 217 IQCVSENSTSDYTLREFLVSWRDQP-ARRIFHYHFQVWPDHGVPADPGCVLNFLQDVNTR 275 Query: 555 --RLYYVG-KDHPIVAHCSAGIGRTGAYITIHNTVERILR-GDQAATNLVETVGKFRSQR 388 L G K PI HCSAGIGRTG +I I +++I+R G ++ T+ RSQR Sbjct: 276 QSHLAQAGEKPGPICVHCSAGIGRTGTFIVIDMILDQIVRNGLDTEIDIQRTIQMVRSQR 335 Query: 387 PGIVQTEEQYKFCYHAIVDELKDLIRNSK 301 G+VQTE QYKF Y+A+ ++ LI + Sbjct: 336 SGLVQTEAQYKFVYYAVQHYIQTLIARKR 364
>PTPRS_HUMAN (Q13332) Receptor-type tyrosine-protein phosphatase S precursor (EC| 3.1.3.48) (R-PTP-S) (Protein-tyrosine phosphatase sigma) (R-PTP-sigma) Length = 1948 Score = 89.7 bits (221), Expect = 8e-18 Identities = 46/123 (37%), Positives = 69/123 (56%), Gaps = 4/123 (3%) Frame = -1 Query: 681 LRSVKVQHKESDRVHTVLHIQHSTWPDHGVPNDSST----VRKILKRLYYVGKDHPIVAH 514 LR KV + TV Q + WP+ GVP + ++ K G+D PI H Sbjct: 1820 LREFKVTDARDGQSRTVRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEQFGQDGPISVH 1879 Query: 513 CSAGIGRTGAYITIHNTVERILRGDQAATNLVETVGKFRSQRPGIVQTEEQYKFCYHAIV 334 CSAG+GRTG +IT+ +ER+ + ++ +TV R+QRP +VQTE++Y+FCY A + Sbjct: 1880 CSAGVGRTGVFITLSIVLERMRY--EGVVDIFQTVKMLRTQRPAMVQTEDEYQFCYQAAL 1937 Query: 333 DEL 325 + L Sbjct: 1938 EYL 1940 Score = 77.8 bits (190), Expect = 3e-14 Identities = 44/134 (32%), Positives = 69/134 (51%), Gaps = 2/134 (1%) Frame = -1 Query: 726 LNIKIVETRQDGELTLRSVKVQHKESDRVHTVLHIQHSTWPDHGVPNDSSTVRKILKRLY 547 + + +++T + +R+ + S V Q + WPDHGVP + L+R+ Sbjct: 1516 IQVTLLDTIELATFCVRTFSLHKNGSSEKREVRQFQFTAWPDHGVPEYPTPFLAFLRRVK 1575 Query: 546 YVGKDH--PIVAHCSAGIGRTGAYITIHNTVERILRGDQAATNLVETVGKFRSQRPGIVQ 373 PIV HCSAG+GRTG +I I +ERI + ++ V RSQR +VQ Sbjct: 1576 TCNPPDAGPIVVHCSAGVGRTGCFIVIDAMLERI--KPEKTVDVYGHVTLMRSQRNYMVQ 1633 Query: 372 TEEQYKFCYHAIVD 331 TE+QY F + A+++ Sbjct: 1634 TEDQYSFIHEALLE 1647
>PTPRF_HUMAN (P10586) Receptor-type tyrosine-protein phosphatase F precursor (EC| 3.1.3.48) (LAR protein) (Leukocyte antigen related) Length = 1897 Score = 88.6 bits (218), Expect = 2e-17 Identities = 45/123 (36%), Positives = 68/123 (55%), Gaps = 4/123 (3%) Frame = -1 Query: 681 LRSVKVQHKESDRVHTVLHIQHSTWPDHGVPNDSST----VRKILKRLYYVGKDHPIVAH 514 LR KV + T+ Q + WP+ GVP + ++ K G+D PI H Sbjct: 1769 LREFKVTDARDGQSRTIRQFQFTDWPEQGVPKTGEGFIDFIGQVHKTKEQFGQDGPITVH 1828 Query: 513 CSAGIGRTGAYITIHNTVERILRGDQAATNLVETVGKFRSQRPGIVQTEEQYKFCYHAIV 334 CSAG+GRTG +IT+ +ER+ + ++ +TV R+QRP +VQTE+QY+ CY A + Sbjct: 1829 CSAGVGRTGVFITLSIVLERMRY--EGVVDMFQTVKTLRTQRPAMVQTEDQYQLCYRAAL 1886 Query: 333 DEL 325 + L Sbjct: 1887 EYL 1889 Score = 75.5 bits (184), Expect = 2e-13 Identities = 42/134 (31%), Positives = 70/134 (52%), Gaps = 2/134 (1%) Frame = -1 Query: 726 LNIKIVETRQDGELTLRSVKVQHKESDRVHTVLHIQHSTWPDHGVPNDSSTVRKILKRLY 547 + + +++T + T+R+ + S + Q WPDHGVP + + L+R+ Sbjct: 1465 IQVTLLDTVELATYTVRTFALHKSGSSEKRELRQFQFMAWPDHGVPEYPTPILAFLRRVK 1524 Query: 546 YVGK--DHPIVAHCSAGIGRTGAYITIHNTVERILRGDQAATNLVETVGKFRSQRPGIVQ 373 P+V HCSAG+GRTG +I I +ER+ + ++ V RSQR +VQ Sbjct: 1525 ACNPLDAGPMVVHCSAGVGRTGCFIVIDAMLERMKH--EKTVDIYGHVTCMRSQRNYMVQ 1582 Query: 372 TEEQYKFCYHAIVD 331 TE+QY F + A+++ Sbjct: 1583 TEDQYVFIHEALLE 1596
>PTN11_CHICK (Q90687) Tyrosine-protein phosphatase non-receptor type 11 (EC| 3.1.3.48) (cSH-PTP2) Length = 593 Score = 88.6 bits (218), Expect = 2e-17 Identities = 51/145 (35%), Positives = 80/145 (55%), Gaps = 6/145 (4%) Frame = -1 Query: 726 LNIKIVETRQDGELTLRSVKVQHK-ESDRVHTVLHIQHSTWPDHGVPNDSSTVRKILKRL 550 + ++ V+ + TLR +K+ + + TV TWPDHGVP+D V L+ + Sbjct: 383 MRVRNVKESAAHDYTLRELKLSKVGQGNTERTVWQYHFRTWPDHGVPSDPGGVLDFLEEV 442 Query: 549 YY----VGKDHPIVAHCSAGIGRTGAYITIHNTVERIL-RGDQAATNLVETVGKFRSQRP 385 ++ + P+V HCSAGIGRTG +I I ++ I +G ++ +T+ RSQR Sbjct: 443 HHKQESISDAGPVVVHCSAGIGRTGTFIVIDILIDIIREKGVDCDIDVPKTIQMVRSQRS 502 Query: 384 GIVQTEEQYKFCYHAIVDELKDLIR 310 G+VQTE QY+F Y A+ ++ L R Sbjct: 503 GMVQTEAQYRFIYMAVQHYIETLQR 527
>LAR_DROME (P16621) Tyrosine-protein phosphatase Lar precursor (EC 3.1.3.48)| (Protein-tyrosine-phosphate phosphohydrolase) (dLAR) Length = 2029 Score = 87.0 bits (214), Expect = 5e-17 Identities = 47/123 (38%), Positives = 66/123 (53%), Gaps = 4/123 (3%) Frame = -1 Query: 681 LRSVKVQHKESDRVHTVLHIQHSTWPDHGVPNDSST----VRKILKRLYYVGKDHPIVAH 514 LR KV TV Q WP+ GVP + ++ K G+D PI H Sbjct: 1901 LREFKVTDARDGSSRTVRQFQFIDWPEQGVPKSGEGFIDFIGQVHKTKEQFGQDGPITVH 1960 Query: 513 CSAGIGRTGAYITIHNTVERILRGDQAATNLVETVGKFRSQRPGIVQTEEQYKFCYHAIV 334 CSAG+GR+G +IT+ +ER+ + ++ +TV RSQRP +VQTE+QY FCY A + Sbjct: 1961 CSAGVGRSGVFITLSIVLERMQY--EGVLDVFQTVRILRSQRPAMVQTEDQYHFCYRAAL 2018 Query: 333 DEL 325 + L Sbjct: 2019 EYL 2021 Score = 79.0 bits (193), Expect = 1e-14 Identities = 42/134 (31%), Positives = 77/134 (57%), Gaps = 2/134 (1%) Frame = -1 Query: 720 IKIVETRQDGELTLRSVKVQHKESDRVHTVLHIQHSTWPDHGVPNDSSTVRKILKRLYYV 541 + I ET++ ++R+ ++ + + + +Q + WPDHGVP+ + + L+R + Sbjct: 1599 VTITETQELATYSIRTFQLCRQGFNDRREIKQLQFTAWPDHGVPDHPAPFLQFLRRCRAL 1658 Query: 540 G--KDHPIVAHCSAGIGRTGAYITIHNTVERILRGDQAATNLVETVGKFRSQRPGIVQTE 367 + P++ HCSAG+GRTG YI I + +ER+ + ++ V R+QR +VQTE Sbjct: 1659 TPPESGPVIVHCSAGVGRTGCYIVIDSMLERMKH--EKIIDIYGHVTCLRAQRNYMVQTE 1716 Query: 366 EQYKFCYHAIVDEL 325 +QY F + AI++ + Sbjct: 1717 DQYIFIHDAILEAI 1730
>CSW_DROVI (Q24708) Tyrosine-protein phosphatase corkscrew (EC 3.1.3.48)| (Fragment) Length = 764 Score = 87.0 bits (214), Expect = 5e-17 Identities = 52/149 (34%), Positives = 74/149 (49%), Gaps = 9/149 (6%) Frame = -1 Query: 720 IKIVETRQDGELTLRSVKVQHKESDRVHTVLHIQHSTWPDHGVPNDSSTVRKILK----- 556 + ++ + TLR ++ + H WPDHGVP D V L+ Sbjct: 384 VHCIKENSTNDYTLREFLFSWRDKPE-RRIYHYHFQVWPDHGVPADPGCVLNFLQDVNTK 442 Query: 555 --RLYYVG-KDHPIVAHCSAGIGRTGAYITIHNTVERILR-GDQAATNLVETVGKFRSQR 388 L G K PI HCSAGIGRTG +I I +++I+R G ++ T+ RSQR Sbjct: 443 QSSLAQAGEKPGPICVHCSAGIGRTGTFIVIDMILDQIVRNGLDTEIDIQRTIQMVRSQR 502 Query: 387 PGIVQTEEQYKFCYHAIVDELKDLIRNSK 301 G+VQTE QYKF Y+A+ ++ LI + Sbjct: 503 SGMVQTEAQYKFVYYAVQHYIQTLIARKR 531
>PTPRD_HUMAN (P23468) Receptor-type tyrosine-protein phosphatase delta precursor| (EC 3.1.3.48) (Protein-tyrosine phosphatase delta) (R-PTP-delta) Length = 1912 Score = 87.0 bits (214), Expect = 5e-17 Identities = 46/123 (37%), Positives = 68/123 (55%), Gaps = 4/123 (3%) Frame = -1 Query: 681 LRSVKVQHKESDRVHTVLHIQHSTWPDHGVPNDSST----VRKILKRLYYVGKDHPIVAH 514 LR KV + TV Q + WP+ GVP + ++ K G+D PI H Sbjct: 1784 LREFKVTDARDGQSRTVRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEQFGQDGPISVH 1843 Query: 513 CSAGIGRTGAYITIHNTVERILRGDQAATNLVETVGKFRSQRPGIVQTEEQYKFCYHAIV 334 CSAG+GRTG +IT+ +ER+ + ++ +TV R+QRP +VQTE+QY+F Y A + Sbjct: 1844 CSAGVGRTGVFITLSIVLERMRY--EGVVDIFQTVKMLRTQRPAMVQTEDQYQFSYRAAL 1901 Query: 333 DEL 325 + L Sbjct: 1902 EYL 1904 Score = 73.9 bits (180), Expect = 5e-13 Identities = 42/134 (31%), Positives = 69/134 (51%), Gaps = 2/134 (1%) Frame = -1 Query: 726 LNIKIVETRQDGELTLRSVKVQHKESDRVHTVLHIQHSTWPDHGVPNDSSTVRKILKRLY 547 + + +++T + +R+ + S V Q + WPDHGVP + L+R+ Sbjct: 1480 VQVTLLDTVELATYCVRTFALYKNGSSEKREVRQFQFTAWPDHGVPEHPTPFLAFLRRVK 1539 Query: 546 YVGKDH--PIVAHCSAGIGRTGAYITIHNTVERILRGDQAATNLVETVGKFRSQRPGIVQ 373 P+V HCSAG+GRTG +I I +ERI + ++ V R+QR +VQ Sbjct: 1540 TCNPPDAGPMVVHCSAGVGRTGCFIVIDAMLERIKH--EKTVDIYGHVTLMRAQRNYMVQ 1597 Query: 372 TEEQYKFCYHAIVD 331 TE+QY F + A+++ Sbjct: 1598 TEDQYIFIHDALLE 1611
>PTPRD_MOUSE (Q64487) Receptor-type tyrosine-protein phosphatase delta precursor| (EC 3.1.3.48) (Protein-tyrosine phosphatase delta) (R-PTP-delta) Length = 1894 Score = 86.3 bits (212), Expect = 9e-17 Identities = 43/108 (39%), Positives = 64/108 (59%), Gaps = 4/108 (3%) Frame = -1 Query: 636 TVLHIQHSTWPDHGVPNDSST----VRKILKRLYYVGKDHPIVAHCSAGIGRTGAYITIH 469 TV Q + WP+ GVP + ++ K G+D PI HCSAG+GRTG +IT+ Sbjct: 1781 TVRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEQFGQDGPISVHCSAGVGRTGVFITLS 1840 Query: 468 NTVERILRGDQAATNLVETVGKFRSQRPGIVQTEEQYKFCYHAIVDEL 325 +ER+ + ++ +TV R+QRP +VQTE+QY+FCY A ++ L Sbjct: 1841 IVLERMRY--EGVVDIFQTVKMLRTQRPAMVQTEDQYQFCYRAALEYL 1886 Score = 69.7 bits (169), Expect = 9e-12 Identities = 40/109 (36%), Positives = 57/109 (52%), Gaps = 2/109 (1%) Frame = -1 Query: 651 SDRVHTVLHIQHSTWPDHGVPNDSSTVRKILKRLYYVGKDH--PIVAHCSAGIGRTGAYI 478 S V Q + WPDHGVP + V L + P+V HCSAG+GRTG +I Sbjct: 1488 SSEKRKVRQFQFTAWPDHGVPEHPTPVPSFLTESQNLHPPDAGPMVVHCSAGVGRTGCFI 1547 Query: 477 TIHNTVERILRGDQAATNLVETVGKFRSQRPGIVQTEEQYKFCYHAIVD 331 I +ERI + ++ V R+QR +VQTE+QY F + A+++ Sbjct: 1548 VIDAMLERIKH--EKTVDIYGHVTLMRAQRNYMVQTEDQYIFIHDALLE 1594
>PTN6_HUMAN (P29350) Tyrosine-protein phosphatase non-receptor type 6 (EC| 3.1.3.48) (Protein-tyrosine phosphatase 1C) (PTP-1C) (Hematopoietic cell protein-tyrosine phosphatase) (SH-PTP1) (Protein-tyrosine phosphatase SHP-1) Length = 595 Score = 86.3 bits (212), Expect = 9e-17 Identities = 50/124 (40%), Positives = 72/124 (58%), Gaps = 6/124 (4%) Frame = -1 Query: 690 ELTLRSVKVQHKES-DRVHTVLHIQHSTWPDHGVPNDSSTVRKIL----KRLYYVGKDHP 526 E LR+++V ++ D + + H Q+ +WPDHGVP++ V L +R + P Sbjct: 389 EYKLRTLQVSPLDNGDLIREIWHYQYLSWPDHGVPSEPGGVLSFLDQINQRQESLPHAGP 448 Query: 525 IVAHCSAGIGRTGAYITIHNTVERI-LRGDQAATNLVETVGKFRSQRPGIVQTEEQYKFC 349 I+ HCSAGIGRTG I I +E I +G ++ +T+ R+QR G+VQTE QYKF Sbjct: 449 IIVHCSAGIGRTGTIIVIDMLMENISTKGLDCDIDIQKTIQMVRAQRSGMVQTEAQYKFI 508 Query: 348 YHAI 337 Y AI Sbjct: 509 YVAI 512
>PTN6_MOUSE (P29351) Tyrosine-protein phosphatase non-receptor type 6 (EC| 3.1.3.48) (Protein-tyrosine phosphatase 1C) (PTP-1C) (Hematopoietic cell protein-tyrosine phosphatase) (70Z-SHP) (SH-PTP1) (SHP-1) (PTPTY-42) Length = 595 Score = 85.9 bits (211), Expect = 1e-16 Identities = 50/124 (40%), Positives = 72/124 (58%), Gaps = 6/124 (4%) Frame = -1 Query: 690 ELTLRSVKVQHKES-DRVHTVLHIQHSTWPDHGVPNDSSTVRKIL----KRLYYVGKDHP 526 E LR++++ ++ D V + H Q+ +WPDHGVP++ V L +R + P Sbjct: 389 EYKLRTLQISPLDNGDLVREIWHYQYLSWPDHGVPSEPGGVLSFLDQINQRQESLPHAGP 448 Query: 525 IVAHCSAGIGRTGAYITIHNTVERI-LRGDQAATNLVETVGKFRSQRPGIVQTEEQYKFC 349 I+ HCSAGIGRTG I I +E I +G ++ +T+ R+QR G+VQTE QYKF Sbjct: 449 IIVHCSAGIGRTGTIIVIDMLMESISTKGLDCDIDIQKTIQMVRAQRSGMVQTEAQYKFI 508 Query: 348 YHAI 337 Y AI Sbjct: 509 YVAI 512
>PTN11_RAT (P41499) Tyrosine-protein phosphatase non-receptor type 11 (EC| 3.1.3.48) (Protein-tyrosine phosphatase SYP) (PTP-1D) (SH-PTP2) (SHP-2) (Shp2) Length = 597 Score = 85.9 bits (211), Expect = 1e-16 Identities = 50/132 (37%), Positives = 72/132 (54%), Gaps = 5/132 (3%) Frame = -1 Query: 690 ELTLRSVKVQHKESDRVHTVLHIQHSTWPDHGVPNDSSTVRKILKRLYYVGKD----HPI 523 EL L V + + TV TWPDHGVP+D V L+ +++ + P+ Sbjct: 400 ELKLSKVGQALLQGNTERTVWQYHFRTWPDHGVPSDPGGVLDFLEEVHHKQESIVDAGPV 459 Query: 522 VAHCSAGIGRTGAYITIHNTVERIL-RGDQAATNLVETVGKFRSQRPGIVQTEEQYKFCY 346 V HCSAGIGRTG +I I ++ I +G ++ +T+ RSQR G+VQTE QY+F Y Sbjct: 460 VVHCSAGIGRTGTFIVIDILIDIIREKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIY 519 Query: 345 HAIVDELKDLIR 310 A+ ++ L R Sbjct: 520 MAVQHYIETLQR 531
>PTN11_MOUSE (P35235) Tyrosine-protein phosphatase non-receptor type 11 (EC| 3.1.3.48) (Protein-tyrosine phosphatase SYP) (SH-PTP2) (SHP-2) (Shp2) Length = 597 Score = 85.9 bits (211), Expect = 1e-16 Identities = 50/132 (37%), Positives = 72/132 (54%), Gaps = 5/132 (3%) Frame = -1 Query: 690 ELTLRSVKVQHKESDRVHTVLHIQHSTWPDHGVPNDSSTVRKILKRLYYVGKD----HPI 523 EL L V + + TV TWPDHGVP+D V L+ +++ + P+ Sbjct: 400 ELKLSKVGQALLQGNTERTVWQYHFRTWPDHGVPSDPGGVLDFLEEVHHKQESIVDAGPV 459 Query: 522 VAHCSAGIGRTGAYITIHNTVERIL-RGDQAATNLVETVGKFRSQRPGIVQTEEQYKFCY 346 V HCSAGIGRTG +I I ++ I +G ++ +T+ RSQR G+VQTE QY+F Y Sbjct: 460 VVHCSAGIGRTGTFIVIDILIDIIREKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIY 519 Query: 345 HAIVDELKDLIR 310 A+ ++ L R Sbjct: 520 MAVQHYIETLQR 531
>PTN11_HUMAN (Q06124) Tyrosine-protein phosphatase non-receptor type 11 (EC| 3.1.3.48) (Protein-tyrosine phosphatase 2C) (PTP-2C) (PTP-1D) (SH-PTP3) (SH-PTP2) (SHP-2) (Shp2) Length = 597 Score = 85.9 bits (211), Expect = 1e-16 Identities = 50/132 (37%), Positives = 72/132 (54%), Gaps = 5/132 (3%) Frame = -1 Query: 690 ELTLRSVKVQHKESDRVHTVLHIQHSTWPDHGVPNDSSTVRKILKRLYYVGKD----HPI 523 EL L V + + TV TWPDHGVP+D V L+ +++ + P+ Sbjct: 400 ELKLSKVGQALLQGNTERTVWQYHFRTWPDHGVPSDPGGVLDFLEEVHHKQESIMDAGPV 459 Query: 522 VAHCSAGIGRTGAYITIHNTVERIL-RGDQAATNLVETVGKFRSQRPGIVQTEEQYKFCY 346 V HCSAGIGRTG +I I ++ I +G ++ +T+ RSQR G+VQTE QY+F Y Sbjct: 460 VVHCSAGIGRTGTFIVIDILIDIIREKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIY 519 Query: 345 HAIVDELKDLIR 310 A+ ++ L R Sbjct: 520 MAVQHYIETLQR 531
>PTN6_RAT (P81718) Tyrosine-protein phosphatase non-receptor type 6 (EC| 3.1.3.48) (Protein-tyrosine phosphatase SHP-1) Length = 613 Score = 85.5 bits (210), Expect = 2e-16 Identities = 49/124 (39%), Positives = 72/124 (58%), Gaps = 6/124 (4%) Frame = -1 Query: 690 ELTLRSVKVQHKES-DRVHTVLHIQHSTWPDHGVPNDSSTVRKIL----KRLYYVGKDHP 526 E LR++++ ++ D V + H Q+ +WPDHGVP++ V L +R + P Sbjct: 391 EYKLRTLQISPLDNGDLVREIWHYQYLSWPDHGVPSEPGGVLSFLDQINQRQESLPHAGP 450 Query: 525 IVAHCSAGIGRTGAYITIHNTVERI-LRGDQAATNLVETVGKFRSQRPGIVQTEEQYKFC 349 I+ HCSAGIGRTG I I +E + +G ++ +T+ R+QR G+VQTE QYKF Sbjct: 451 IIVHCSAGIGRTGTIIVIDMLMESVSTKGLDCDIDIQKTIQMVRAQRSGMVQTEAQYKFI 510 Query: 348 YHAI 337 Y AI Sbjct: 511 YVAI 514
>PTN3_HUMAN (P26045) Tyrosine-protein phosphatase non-receptor type 3 (EC| 3.1.3.48) (Protein-tyrosine phosphatase H1) (PTP-H1) Length = 913 Score = 82.8 bits (203), Expect = 1e-15 Identities = 44/116 (37%), Positives = 65/116 (56%), Gaps = 1/116 (0%) Frame = -1 Query: 678 RSVKVQHKESDRVHTVLHIQHSTWPDHGVPNDSSTVRKILKRLYYVGKD-HPIVAHCSAG 502 R + V + ++ HTV H+Q+ WPDHG+P+DSS + + + + D P++ HCSAG Sbjct: 786 REMLVTNTQTGEEHTVTHLQYVAWPDHGIPDDSSDFLEFVNYVRSLRVDSEPVLVHCSAG 845 Query: 501 IGRTGAYITIHNTVERILRGDQAATNLVETVGKFRSQRPGIVQTEEQYKFCYHAIV 334 IGRTG +T+ + L ++ V K R QR +VQT QYKF AI+ Sbjct: 846 IGRTGVLVTMETAM--CLTERNLPIYPLDIVRKMRDQRAMMVQTSSQYKFVCEAIL 899
>PTPRT_MOUSE (Q99M80) Receptor-type tyrosine-protein phosphatase T precursor (EC| 3.1.3.48) (R-PTP-T) (RPTP-rho) (mRPTPrho) (RPTPmam4) Length = 1454 Score = 82.4 bits (202), Expect = 1e-15 Identities = 42/134 (31%), Positives = 75/134 (55%), Gaps = 2/134 (1%) Frame = -1 Query: 726 LNIKIVETRQDGELTLRSVKVQHKESDRVHTVLHIQHSTWPDHGVPNDSSTVRKILKRLY 547 + + ++ET E +R+ VQ K + + ++WPDHGVP ++ + ++++ Sbjct: 1024 IKVTLIETEPLAEYVIRTFTVQKKGYHEIRELRLFHFTSWPDHGVPCYATGLLGFVRQVK 1083 Query: 546 YVGKDH--PIVAHCSAGIGRTGAYITIHNTVERILRGDQAATNLVETVGKFRSQRPGIVQ 373 ++ PIV HCSAG GRTG +I I ++ + ++ ++ V + R+QR +VQ Sbjct: 1084 FLNPPEAGPIVVHCSAGAGRTGCFIAIDTMLD--MAENEGVVDIFNCVRELRAQRVNLVQ 1141 Query: 372 TEEQYKFCYHAIVD 331 TEEQY F + AI++ Sbjct: 1142 TEEQYVFVHDAILE 1155 Score = 54.7 bits (130), Expect = 3e-07 Identities = 37/142 (26%), Positives = 68/142 (47%), Gaps = 8/142 (5%) Frame = -1 Query: 726 LNIKIVETRQDGELTLRSVKVQH--KESDRVHTVLHIQHSTWPDH-GVPNDSSTVRKILK 556 + ++ V D ++ R ++ + + D V H+Q+ WP + P ++ K+++ Sbjct: 1312 IQVEFVSADIDEDIIHRIFRICNMARPQDGYRIVQHLQYIGWPAYRDTPPSKRSLLKVVR 1371 Query: 555 RL-----YYVGKDHPIVAHCSAGIGRTGAYITIHNTVERILRGDQAATNLVETVGKFRSQ 391 RL Y G++ V HC G GR+G + I + E I + Q ++ V R+ Sbjct: 1372 RLEKWQEQYDGREGRTVVHCLNGGGRSGTFCAICSVCEMIQQ--QNIIDVFHIVKTLRNN 1429 Query: 390 RPGIVQTEEQYKFCYHAIVDEL 325 + +V+T EQYKF Y ++ L Sbjct: 1430 KSNMVETLEQYKFVYEVALEYL 1451
>PTPRT_HUMAN (O14522) Receptor-type tyrosine-protein phosphatase T precursor (EC| 3.1.3.48) (R-PTP-T) (RPTP-rho) Length = 1463 Score = 82.4 bits (202), Expect = 1e-15 Identities = 42/134 (31%), Positives = 75/134 (55%), Gaps = 2/134 (1%) Frame = -1 Query: 726 LNIKIVETRQDGELTLRSVKVQHKESDRVHTVLHIQHSTWPDHGVPNDSSTVRKILKRLY 547 + + ++ET E +R+ VQ K + + ++WPDHGVP ++ + ++++ Sbjct: 1033 IKVTLIETEPLAEYVIRTFTVQKKGYHEIRELRLFHFTSWPDHGVPCYATGLLGFVRQVK 1092 Query: 546 YVGKDH--PIVAHCSAGIGRTGAYITIHNTVERILRGDQAATNLVETVGKFRSQRPGIVQ 373 ++ PIV HCSAG GRTG +I I ++ + ++ ++ V + R+QR +VQ Sbjct: 1093 FLNPPEAGPIVVHCSAGAGRTGCFIAIDTMLD--MAENEGVVDIFNCVRELRAQRVNLVQ 1150 Query: 372 TEEQYKFCYHAIVD 331 TEEQY F + AI++ Sbjct: 1151 TEEQYVFVHDAILE 1164 Score = 54.7 bits (130), Expect = 3e-07 Identities = 37/142 (26%), Positives = 68/142 (47%), Gaps = 8/142 (5%) Frame = -1 Query: 726 LNIKIVETRQDGELTLRSVKVQH--KESDRVHTVLHIQHSTWPDH-GVPNDSSTVRKILK 556 + ++ V D ++ R ++ + + D V H+Q+ WP + P ++ K+++ Sbjct: 1321 IQVEFVSADIDEDIIHRIFRICNMARPQDGYRIVQHLQYIGWPAYRDTPPSKRSLLKVVR 1380 Query: 555 RL-----YYVGKDHPIVAHCSAGIGRTGAYITIHNTVERILRGDQAATNLVETVGKFRSQ 391 RL Y G++ V HC G GR+G + I + E I + Q ++ V R+ Sbjct: 1381 RLEKWQEQYDGREGRTVVHCLNGGGRSGTFCAICSVCEMIQQ--QNIIDVFHIVKTLRNN 1438 Query: 390 RPGIVQTEEQYKFCYHAIVDEL 325 + +V+T EQYKF Y ++ L Sbjct: 1439 KSNMVETLEQYKFVYEVALEYL 1460
>PTN18_MOUSE (Q61152) Tyrosine-protein phosphatase non-receptor type 18 (EC| 3.1.3.48) (Fetal liver phosphatase 1) (FLP-1) (PTP-K1) Length = 453 Score = 81.3 bits (199), Expect = 3e-15 Identities = 48/129 (37%), Positives = 75/129 (58%), Gaps = 5/129 (3%) Frame = -1 Query: 708 ETRQDGELTLRSVKVQHKESDRVHTVLHIQHSTWPDHGVPNDSSTVRKILKR---LYYVG 538 ET + ++TLR+++V ++ R +V +Q+ +WPDHGVP+ S + +++ L +G Sbjct: 164 ETTLNADITLRTLQVTFQKEFR--SVHQLQYMSWPDHGVPSSSDHILTMVEEARCLQGLG 221 Query: 537 KDHPIVAHCSAGIGRTGAYITIHNTVERILRGDQAATN--LVETVGKFRSQRPGIVQTEE 364 P+ HCSAG GRTG + + V ++L N L + V + R QRP VQTEE Sbjct: 222 PG-PLCVHCSAGCGRTGVLCAV-DYVRQLLLTQTIPPNFSLFQVVLEMRKQRPAAVQTEE 279 Query: 363 QYKFCYHAI 337 QY+F YH + Sbjct: 280 QYRFLYHTV 288
>PTPR2_MACNE (O02695) Receptor-type tyrosine-protein phosphatase N2 precursor (EC| 3.1.3.48) (R-PTP-N2) (M1851) Length = 1013 Score = 80.5 bits (197), Expect = 5e-15 Identities = 38/129 (29%), Positives = 75/129 (58%), Gaps = 2/129 (1%) Frame = -1 Query: 690 ELTLRSVKVQHKESDRVHTVLHIQHSTWPDHGVPNDSSTVRKILKRLY--YVGKDHPIVA 517 + +RS +++ +++ TV +W D GVP+ S ++ +++ Y G+ PI+ Sbjct: 882 DFLVRSFYLKNLQTNETRTVTQFHFLSWYDRGVPSSSRSLLDFRRKVNKCYRGRSCPIIV 941 Query: 516 HCSAGIGRTGAYITIHNTVERILRGDQAATNLVETVGKFRSQRPGIVQTEEQYKFCYHAI 337 HCS G GR+G Y+ I + ++ +G + ++ T+ R QRPG+VQT+EQ++F A+ Sbjct: 942 HCSDGAGRSGTYVLIDMVLNKMAKGAK-EIDIAATLEHLRDQRPGMVQTKEQFEFALTAV 1000 Query: 336 VDELKDLIR 310 +E+ +++ Sbjct: 1001 AEEVNAILK 1009
>PTPR2_HUMAN (Q92932) Receptor-type tyrosine-protein phosphatase N2 precursor (EC| 3.1.3.48) (R-PTP-N2) (Islet cell autoantigen-related protein) (ICAAR) (IAR) (Phogrin) Length = 1015 Score = 80.5 bits (197), Expect = 5e-15 Identities = 38/129 (29%), Positives = 75/129 (58%), Gaps = 2/129 (1%) Frame = -1 Query: 690 ELTLRSVKVQHKESDRVHTVLHIQHSTWPDHGVPNDSSTVRKILKRLY--YVGKDHPIVA 517 + +RS +++ +++ TV +W D GVP+ S ++ +++ Y G+ PI+ Sbjct: 884 DFLVRSFYLKNLQTNETRTVTQFHFLSWYDRGVPSSSRSLLDFRRKVNKCYRGRSCPIIV 943 Query: 516 HCSAGIGRTGAYITIHNTVERILRGDQAATNLVETVGKFRSQRPGIVQTEEQYKFCYHAI 337 HCS G GR+G Y+ I + ++ +G + ++ T+ R QRPG+VQT+EQ++F A+ Sbjct: 944 HCSDGAGRSGTYVLIDMVLNKMAKGAK-EIDIAATLEHLRDQRPGMVQTKEQFEFALTAV 1002 Query: 336 VDELKDLIR 310 +E+ +++ Sbjct: 1003 AEEVNAILK 1011
>PTN7_MOUSE (Q8BUM3) Tyrosine-protein phosphatase non-receptor type 7 (EC| 3.1.3.48) Length = 359 Score = 80.1 bits (196), Expect = 6e-15 Identities = 44/132 (33%), Positives = 74/132 (56%), Gaps = 4/132 (3%) Frame = -1 Query: 720 IKIVETRQDGELTLRSVKVQHKESDRVHTVLHIQHSTWPDHGVPNDSSTVRKILKRLYY- 544 I+I + ++ E T+R + +QH++ R +V HI S WPDH P + + +++ + Sbjct: 220 IRIQDMKEHPEYTVRQLTIQHQQECR--SVKHILFSAWPDHQTPESAGPLLRLVAEVETP 277 Query: 543 --VGKDHPIVAHCSAGIGRTGAYITIHNTVERI-LRGDQAATNLVETVGKFRSQRPGIVQ 373 PIV HCSAGIGRTG +I +++ RG+ +++ V + R R G++Q Sbjct: 278 ETAANSGPIVVHCSAGIGRTGCFIATRIGCQQLKARGE---VDILGIVCQLRLDRGGMIQ 334 Query: 372 TEEQYKFCYHAI 337 T EQY+F +H + Sbjct: 335 TAEQYQFLHHTL 346
>PTPR2_MOUSE (P80560) Receptor-type tyrosine-protein phosphatase N2 precursor (EC| 3.1.3.48) (R-PTP-N2) (PTP IA-2beta) (Protein tyrosine phosphatase-NP) (PTP-NP) Length = 1001 Score = 79.3 bits (194), Expect = 1e-14 Identities = 37/129 (28%), Positives = 75/129 (58%), Gaps = 2/129 (1%) Frame = -1 Query: 690 ELTLRSVKVQHKESDRVHTVLHIQHSTWPDHGVPNDSSTVRKILKRLY--YVGKDHPIVA 517 + +RS +++ +++ TV +W D GVP+ + ++ +++ Y G+ PI+ Sbjct: 870 DFLVRSFYLKNLQTNETRTVTQFHFLSWYDQGVPSSTRSLLDFRRKVNKCYRGRSCPIIV 929 Query: 516 HCSAGIGRTGAYITIHNTVERILRGDQAATNLVETVGKFRSQRPGIVQTEEQYKFCYHAI 337 HCS G GR+G Y+ I + ++ +G + ++ T+ R QRPG+VQT+EQ++F A+ Sbjct: 930 HCSDGAGRSGTYVLIDMVLNKMAKGAK-EIDIAATLEHLRDQRPGMVQTKEQFEFALTAV 988 Query: 336 VDELKDLIR 310 +E+ +++ Sbjct: 989 AEEVNAILK 997
>PTN18_HUMAN (Q99952) Tyrosine-protein phosphatase non-receptor type 18 (EC| 3.1.3.48) (Brain-derived phosphatase) Length = 458 Score = 79.3 bits (194), Expect = 1e-14 Identities = 47/134 (35%), Positives = 75/134 (55%), Gaps = 5/134 (3%) Frame = -1 Query: 690 ELTLRSVKVQHKESDRVHTVLHIQHSTWPDHGVPNDSSTVRKIL---KRLYYVGKDHPIV 520 ++ LR++KV ++ R +V +Q+ +WPD GVP+ + ++ +RL G + P+ Sbjct: 170 DIMLRTLKVTFQKESR--SVYQLQYMSWPDRGVPSSPDHMLAMVEEARRLQGSGPE-PLC 226 Query: 519 AHCSAGIGRTGAYITIHNTVERILRGDQAATN--LVETVGKFRSQRPGIVQTEEQYKFCY 346 HCSAG GRTG T+ + V ++L + L + V K R QRP VQTEEQY+F Y Sbjct: 227 VHCSAGCGRTGVLCTV-DYVRQLLLTQMIPPDFSLFDVVLKMRKQRPAAVQTEEQYRFLY 285 Query: 345 HAIVDELKDLIRNS 304 H + ++N+ Sbjct: 286 HTVAQMFCSTLQNA 299
>PTN13_HUMAN (Q12923) Tyrosine-protein phosphatase non-receptor type 13 (EC| 3.1.3.48) (Protein-tyrosine phosphatase 1E) (PTP-E1) (hPTPE1) (PTP-BAS) (Protein-tyrosine phosphatase PTPL1) (Fas-associated protein-tyrosine phosphatase 1) (FAP-1) Length = 2485 Score = 79.3 bits (194), Expect = 1e-14 Identities = 40/131 (30%), Positives = 69/131 (52%) Frame = -1 Query: 726 LNIKIVETRQDGELTLRSVKVQHKESDRVHTVLHIQHSTWPDHGVPNDSSTVRKILKRLY 547 L + +V +Q +R++ ++ ++ V + H+ + WPDH P+ + + + Sbjct: 2337 LRLALVRMQQLKGFVVRAMTLEDIQTREVRHISHLNFTAWPDHDTPSQPDDLLTFISYMR 2396 Query: 546 YVGKDHPIVAHCSAGIGRTGAYITIHNTVERILRGDQAATNLVETVGKFRSQRPGIVQTE 367 ++ + PI+ HCSAGIGR+G I I + I ++ + V R QR G+VQTE Sbjct: 2397 HIHRSGPIITHCSAGIGRSGTLICIDVVLGLI--SQDLDFDISDLVRCMRLQRHGMVQTE 2454 Query: 366 EQYKFCYHAIV 334 +QY FCY I+ Sbjct: 2455 DQYIFCYQVIL 2465
>PTPR2_RAT (Q63475) Receptor-type tyrosine-protein phosphatase N2 precursor (EC| 3.1.3.48) (R-PTP-N2) (PTP NE-6) (PTPNE6) (Phogrin) Length = 1004 Score = 79.3 bits (194), Expect = 1e-14 Identities = 37/129 (28%), Positives = 75/129 (58%), Gaps = 2/129 (1%) Frame = -1 Query: 690 ELTLRSVKVQHKESDRVHTVLHIQHSTWPDHGVPNDSSTVRKILKRLY--YVGKDHPIVA 517 + +RS +++ +++ TV +W D GVP+ + ++ +++ Y G+ PI+ Sbjct: 873 DFLVRSFYLKNLQTNETRTVTQFHFLSWYDQGVPSSTRSLLDFRRKVNKCYRGRSCPIIV 932 Query: 516 HCSAGIGRTGAYITIHNTVERILRGDQAATNLVETVGKFRSQRPGIVQTEEQYKFCYHAI 337 HCS G GR+G Y+ I + ++ +G + ++ T+ R QRPG+VQT+EQ++F A+ Sbjct: 933 HCSDGAGRSGTYVLIDMVLNKMAKGAK-EIDIAATLEHLRDQRPGMVQTKEQFEFALTAV 991 Query: 336 VDELKDLIR 310 +E+ +++ Sbjct: 992 AEEVNAILK 1000
>PTP99_DROME (P35832) Tyrosine-protein phosphatase 99A precursor (EC 3.1.3.48)| (Receptor-linked protein-tyrosine phosphatase 99A) (DPTP99A) Length = 1301 Score = 79.0 bits (193), Expect = 1e-14 Identities = 44/142 (30%), Positives = 76/142 (53%), Gaps = 8/142 (5%) Frame = -1 Query: 726 LNIKIVETRQDGELTLRSVKVQH------KESDRVHTVLHIQHSTWPDHGVPNDSSTVRK 565 + +K++E T+R+++++H K+ + V ++ WPDHG P+ V Sbjct: 603 IQVKLIEEEVMSTYTVRTLQIKHLKLKKKKQCNTEKLVYQYHYTNWPDHGTPDHPLPVLN 662 Query: 564 ILKRLYYVGKDH--PIVAHCSAGIGRTGAYITIHNTVERILRGDQAATNLVETVGKFRSQ 391 +K+ PIV HCSAG+GRTG YI + +++I + + N+ + R+Q Sbjct: 663 FVKKSSAANPAEAGPIVVHCSAGVGRTGTYIVLDAMLKQIQQ--KNIVNVFGFLRHIRAQ 720 Query: 390 RPGIVQTEEQYKFCYHAIVDEL 325 R +VQTEEQY F + A+V+ + Sbjct: 721 RNFLVQTEEQYIFLHDALVEAI 742
>CD45_HUMAN (P08575) Leukocyte common antigen precursor (EC 3.1.3.48) (L-CA)| (CD45 antigen) (T200) Length = 1304 Score = 78.6 bits (192), Expect = 2e-14 Identities = 48/117 (41%), Positives = 62/117 (52%), Gaps = 5/117 (4%) Frame = -1 Query: 666 VQHKESDRVHTVLHIQHSTWPDHGVPNDSSTVRKILKRLYYVGK--DHPIVAHCSAGIGR 493 V KE V HIQ ++WPDHGVP D + K+ +R+ PIV HCSAG+GR Sbjct: 798 VNKKEKATGREVTHIQFTSWPDHGVPEDPHLLLKLRRRVNAFSNFFSGPIVVHCSAGVGR 857 Query: 492 TGAYITIHNTVERILRGDQAATNLVETVG---KFRSQRPGIVQTEEQYKFCYHAIVD 331 TG YI I +E + A N V+ G K R QR +VQ E QY + A+V+ Sbjct: 858 TGTYIGIDAMLEGL-----EAENKVDVYGYVVKLRRQRCLMVQVEAQYILIHQALVE 909 Score = 53.9 bits (128), Expect = 5e-07 Identities = 34/142 (23%), Positives = 64/142 (45%), Gaps = 12/142 (8%) Frame = -1 Query: 726 LNIKIVETRQDGELTLRSVKVQHKESDRVHTVLHIQHSTWPDHGVPNDSSTV-------- 571 + + + +T + TLR +++H + TV Q++ W +P + + Sbjct: 1084 IEVDLKDTDKSSTYTLRVFELRHSKRKDSRTVYQYQYTNWSVEQLPAEPKELISMIQVVK 1143 Query: 570 RKILKRLYYVGKDH----PIVAHCSAGIGRTGAYITIHNTVERILRGDQAATNLVETVGK 403 +K+ ++ G H P++ HC G +TG + + N +E + ++ + V Sbjct: 1144 QKLPQKNSSEGNKHHKSTPLLIHCRDGSQQTGIFCALLNLLESA--ETEEVVDIFQVVKA 1201 Query: 402 FRSQRPGIVQTEEQYKFCYHAI 337 R RPG+V T EQY+F Y I Sbjct: 1202 LRKARPGMVSTFEQYQFLYDVI 1223
>PTPRA_HUMAN (P18433) Receptor-type tyrosine-protein phosphatase alpha precursor| (EC 3.1.3.48) (Protein-tyrosine phosphatase alpha) (R-PTP-alpha) Length = 802 Score = 78.2 bits (191), Expect = 2e-14 Identities = 40/134 (29%), Positives = 70/134 (52%), Gaps = 4/134 (2%) Frame = -1 Query: 726 LNIKIVETRQDGELTLRSVKVQHKESDRVHTVLHIQHSTWPDHGVPNDS----STVRKIL 559 + +++ + + T+R + V + ++ + WP+ G+P+D S + + Sbjct: 658 ITVELKKEEECESYTVRDLLVTNTRENKSRQIRQFHFHGWPEVGIPSDGKGMISIIAAVQ 717 Query: 558 KRLYYVGKDHPIVAHCSAGIGRTGAYITIHNTVERILRGDQAATNLVETVGKFRSQRPGI 379 K+ G +HPI HCSAG GRTG + + +ER+ + ++ +TV R QRP + Sbjct: 718 KQQQQSG-NHPITVHCSAGAGRTGTFCALSTVLERVKA--EGILDVFQTVKSLRLQRPHM 774 Query: 378 VQTEEQYKFCYHAI 337 VQT EQY+FCY + Sbjct: 775 VQTLEQYEFCYKVV 788 Score = 63.5 bits (153), Expect = 6e-10 Identities = 36/112 (32%), Positives = 62/112 (55%), Gaps = 2/112 (1%) Frame = -1 Query: 660 HKESDRVHTVLHIQHSTWPDHGVPNDSSTVRKILKRLYYVGKDHP--IVAHCSAGIGRTG 487 +++ R+ T H ++WPD GVP + K LK++ + IV HCSAG+GRTG Sbjct: 393 NRKPQRLITQFHF--TSWPDFGVPFTPIGMLKFLKKVKACNPQYAGAIVVHCSAGVGRTG 450 Query: 486 AYITIHNTVERILRGDQAATNLVETVGKFRSQRPGIVQTEEQYKFCYHAIVD 331 ++ I ++ + + ++ V + R+QR +VQT+ QY F Y A+++ Sbjct: 451 TFVVIDAMLD--MMHTERKVDVYGFVSRIRAQRCQMVQTDMQYVFIYQALLE 500
>PTPRO_HUMAN (Q16827) Receptor-type tyrosine-protein phosphatase O precursor (EC| 3.1.3.48) (Glomerular epithelial protein 1) (Protein tyrosine phosphatase U2) (PTPase U2) (PTP-U2) Length = 1216 Score = 78.2 bits (191), Expect = 2e-14 Identities = 39/135 (28%), Positives = 74/135 (54%), Gaps = 5/135 (3%) Frame = -1 Query: 726 LNIKIVETRQDGELTLRSVKVQHKESDRVHTVLHIQHSTWPDHGVPNDSSTVRKILKRLY 547 + ++++ + + R ++ + +D + V+H ++ WPDHGVP ++ IL+ ++ Sbjct: 1063 ITVEMISEEEQDDWACRHFRINY--ADEMQDVMHFNYTAWPDHGVPT-ANAAESILQFVH 1119 Query: 546 YVGKDH-----PIVAHCSAGIGRTGAYITIHNTVERILRGDQAATNLVETVGKFRSQRPG 382 V + P++ HCSAG+GRTG +I + ++ I D +++ V + RS R Sbjct: 1120 MVRQQATKSKGPMIIHCSAGVGRTGTFIALDRLLQHI--RDHEFVDILGLVSEMRSYRMS 1177 Query: 381 IVQTEEQYKFCYHAI 337 +VQTEEQY F + + Sbjct: 1178 MVQTEEQYIFIHQCV 1192
>PTPRZ_HUMAN (P23471) Receptor-type tyrosine-protein phosphatase zeta precursor| (EC 3.1.3.48) (R-PTP-zeta) Length = 2314 Score = 78.2 bits (191), Expect = 2e-14 Identities = 48/128 (37%), Positives = 72/128 (56%), Gaps = 8/128 (6%) Frame = -1 Query: 684 TLRSVKVQH-----KESDRVHTVLHIQHSTWPDHGVPNDSSTVRKILKRLYYVGKDH--- 529 TLR+ K++ + S RV T H ++ WPD GVP S V +++ Y K H Sbjct: 1870 TLRNTKIKKGSQKGRPSGRVVTQYH--YTQWPDMGVPEYSLPVLTFVRKAAYA-KRHAVG 1926 Query: 528 PIVAHCSAGIGRTGAYITIHNTVERILRGDQAATNLVETVGKFRSQRPGIVQTEEQYKFC 349 P+V HCSAG+GRTG YI + + +++I + N+ + RSQR +VQTEEQY F Sbjct: 1927 PVVVHCSAGVGRTGTYIVLDSMLQQIQH--EGTVNIFGFLKHIRSQRNYLVQTEEQYVFI 1984 Query: 348 YHAIVDEL 325 + +V+ + Sbjct: 1985 HDTLVEAI 1992 Score = 36.6 bits (83), Expect = 0.081 Identities = 23/119 (19%), Positives = 50/119 (42%) Frame = -1 Query: 690 ELTLRSVKVQHKESDRVHTVLHIQHSTWPDHGVPNDSSTVRKILKRLYYVGKDHPIVAHC 511 +L ++ ++ + D V V H Q WP+ P + + + +D P++ H Sbjct: 2163 KLIIQDFILEATQDDYVLEVRHFQCPKWPNPDSPISKTFELISVIKEEAANRDGPMIVHD 2222 Query: 510 SAGIGRTGAYITIHNTVERILRGDQAATNLVETVGKFRSQRPGIVQTEEQYKFCYHAIV 334 G G + + + ++ + + + ++ + RPG+ EQY+F Y I+ Sbjct: 2223 EHGGVTAGTFCALTTLMHQLEK--ENSVDVYQVAKMINLMRPGVFADIEQYQFLYKVIL 2279
>PTN7_RAT (P49445) Tyrosine-protein phosphatase non-receptor type 7 (EC| 3.1.3.48) (Protein-tyrosine phosphatase LC-PTP) (Hematopoietic protein-tyrosine phosphatase) (HEPTP) Length = 359 Score = 78.2 bits (191), Expect = 2e-14 Identities = 44/132 (33%), Positives = 73/132 (55%), Gaps = 4/132 (3%) Frame = -1 Query: 720 IKIVETRQDGELTLRSVKVQHKESDRVHTVLHIQHSTWPDHGVPNDSSTVRKILKRLYY- 544 I+I ++ E T+R + +QH++ R +V HI S WPDH P + + +++ + Sbjct: 220 IRIQGMKEHPEYTVRHLTIQHQQECR--SVKHILFSAWPDHQTPESAGPLLRLVAEVETP 277 Query: 543 --VGKDHPIVAHCSAGIGRTGAYITIHNTVERI-LRGDQAATNLVETVGKFRSQRPGIVQ 373 PIV HCSAGIGRTG +I +++ RG+ +++ V + R R G++Q Sbjct: 278 ETAANSGPIVVHCSAGIGRTGCFIATRIGCQQLKARGE---VDILGIVCQLRLDRGGMIQ 334 Query: 372 TEEQYKFCYHAI 337 T EQY+F +H + Sbjct: 335 TAEQYQFLHHTL 346
>PTPRE_HUMAN (P23469) Receptor-type tyrosine-protein phosphatase epsilon| precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase epsilon) (R-PTP-epsilon) Length = 700 Score = 78.2 bits (191), Expect = 2e-14 Identities = 40/115 (34%), Positives = 62/115 (53%), Gaps = 4/115 (3%) Frame = -1 Query: 663 QHKESDRVHTVLHIQHSTWPDHGVPNDSS----TVRKILKRLYYVGKDHPIVAHCSAGIG 496 Q ++ ++V V WP+ G+P + + + K+ G +HPI HCSAG G Sbjct: 577 QARQEEQVRVVRQFHFHGWPEIGIPAEGKGMIDLIAAVQKQQQQTG-NHPITVHCSAGAG 635 Query: 495 RTGAYITIHNTVERILRGDQAATNLVETVGKFRSQRPGIVQTEEQYKFCYHAIVD 331 RTG +I + N +ER+ + ++ + V R QRP +VQT EQY+FCY + D Sbjct: 636 RTGTFIALSNILERVKA--EGLLDVFQAVKSLRLQRPHMVQTLEQYEFCYKVVQD 688 Score = 75.5 bits (184), Expect = 2e-13 Identities = 40/103 (38%), Positives = 63/103 (61%), Gaps = 2/103 (1%) Frame = -1 Query: 633 VLHIQHSTWPDHGVPNDSSTVRKILKRLYYVGKDH--PIVAHCSAGIGRTGAYITIHNTV 460 V + ++WPD GVP + K LK++ + H PIV HCSAG+GRTG +I I + + Sbjct: 293 VSQLHFTSWPDFGVPFTPIGMLKFLKKVKTLNPVHAGPIVVHCSAGVGRTGTFIVI-DAM 351 Query: 459 ERILRGDQAATNLVETVGKFRSQRPGIVQTEEQYKFCYHAIVD 331 ++ +Q ++ E V + R+QRP +VQT+ QY F Y A+++ Sbjct: 352 MAMMHAEQ-KVDVFEFVSRIRNQRPQMVQTDMQYTFIYQALLE 393
>PTPRA_MOUSE (P18052) Receptor-type tyrosine-protein phosphatase alpha precursor| (EC 3.1.3.48) (Protein-tyrosine phosphatase alpha) (R-PTP-alpha) (LCA-related phosphatase) (PTPTY-28) Length = 829 Score = 77.8 bits (190), Expect = 3e-14 Identities = 38/133 (28%), Positives = 69/133 (51%), Gaps = 3/133 (2%) Frame = -1 Query: 726 LNIKIVETRQDGELTLRSVKVQHKESDRVHTVLHIQHSTWPDHGVPNDSSTVRKIL---K 556 + +++ + + T+R + V + ++ + WP+ G+P+D + I+ + Sbjct: 685 ITVELKKEEECESYTVRDLLVTNTRENKSRQIRQFHFHGWPEVGIPSDGKGMINIIAAVQ 744 Query: 555 RLYYVGKDHPIVAHCSAGIGRTGAYITIHNTVERILRGDQAATNLVETVGKFRSQRPGIV 376 + +HPI HCSAG GRTG + + +ER+ + ++ +TV R QRP +V Sbjct: 745 KQQQQSGNHPITVHCSAGAGRTGTFCALSTVLERVKA--EGILDVFQTVKSLRLQRPHMV 802 Query: 375 QTEEQYKFCYHAI 337 QT EQY+FCY + Sbjct: 803 QTLEQYEFCYKVV 815 Score = 65.1 bits (157), Expect = 2e-10 Identities = 37/114 (32%), Positives = 63/114 (55%), Gaps = 2/114 (1%) Frame = -1 Query: 666 VQHKESDRVHTVLHIQHSTWPDHGVPNDSSTVRKILKRLYYVGKDHP--IVAHCSAGIGR 493 V +++ R+ T H ++WPD GVP + K LK++ + IV HCSAG+GR Sbjct: 418 VTNRKPQRLITQFHF--TSWPDFGVPFTPIGMLKFLKKVKACNPQYAGAIVVHCSAGVGR 475 Query: 492 TGAYITIHNTVERILRGDQAATNLVETVGKFRSQRPGIVQTEEQYKFCYHAIVD 331 TG ++ I ++ + + ++ V + R+QR +VQT+ QY F Y A+++ Sbjct: 476 TGTFVVIDAMLD--MMHSERKVDVYGFVSRIRAQRCQMVQTDMQYVFIYQALLE 527
>PTPRG_CHICK (Q98936) Receptor-type tyrosine-protein phosphatase gamma precursor| (EC 3.1.3.48) (Protein-tyrosine phosphatase gamma) (R-PTP-gamma) Length = 1422 Score = 77.8 bits (190), Expect = 3e-14 Identities = 42/117 (35%), Positives = 71/117 (60%), Gaps = 2/117 (1%) Frame = -1 Query: 669 KVQHKESDRVHTVLHIQHSTWPDHGVPNDSSTVRKILKRLYYVGKDH--PIVAHCSAGIG 496 K + ++++R TV+ ++ WPD GVP + V ++R H P+V HCSAG+G Sbjct: 985 KPKGRQNER--TVIQYHYTQWPDMGVPEYALPVLTFVRRSSAARTPHMGPVVVHCSAGVG 1042 Query: 495 RTGAYITIHNTVERILRGDQAATNLVETVGKFRSQRPGIVQTEEQYKFCYHAIVDEL 325 RTG YI I + +++I D++ N++ + R+QR +VQTEEQY F + A+++ + Sbjct: 1043 RTGTYIVIDSMLQQI--KDKSTVNVLGFLKHIRTQRNYLVQTEEQYIFIHDALLEAI 1097 Score = 37.4 bits (85), Expect = 0.047 Identities = 24/119 (20%), Positives = 50/119 (42%) Frame = -1 Query: 690 ELTLRSVKVQHKESDRVHTVLHIQHSTWPDHGVPNDSSTVRKILKRLYYVGKDHPIVAHC 511 ++ + ++ + D V V H Q WP+ P S+ + + + +D P + H Sbjct: 1269 QIIIHDFILEATQDDYVLEVRHFQCPKWPNPDAPISSTFELINVIKEEALTRDGPTIVHD 1328 Query: 510 SAGIGRTGAYITIHNTVERILRGDQAATNLVETVGKFRSQRPGIVQTEEQYKFCYHAIV 334 G G + +++ ++ A ++ + RPG+ EQY+F Y A++ Sbjct: 1329 EYGAVSAGTLCALTTLSQQL--ENENAVDVFQVAKMINLMRPGVFTDIEQYQFLYKAML 1385
>PTPRE_MOUSE (P49446) Receptor-type tyrosine-protein phosphatase epsilon| precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase epsilon) (R-PTP-epsilon) Length = 699 Score = 77.8 bits (190), Expect = 3e-14 Identities = 40/103 (38%), Positives = 61/103 (59%), Gaps = 2/103 (1%) Frame = -1 Query: 633 VLHIQHSTWPDHGVPNDSSTVRKILKRLYYVGKDH--PIVAHCSAGIGRTGAYITIHNTV 460 V + ++WPD GVP + K LK++ + H PIV HCSAG+GRTG +I I + Sbjct: 292 VSQLHFTSWPDFGVPFTPIGMLKFLKKVKTLNPSHAGPIVVHCSAGVGRTGTFIVIDAMM 351 Query: 459 ERILRGDQAATNLVETVGKFRSQRPGIVQTEEQYKFCYHAIVD 331 + I + ++ E V + R+QRP +VQT+ QY F Y A+++ Sbjct: 352 DMI--HSEQKVDVFEFVSRIRNQRPQMVQTDVQYTFIYQALLE 392 Score = 76.6 bits (187), Expect = 7e-14 Identities = 39/113 (34%), Positives = 61/113 (53%), Gaps = 4/113 (3%) Frame = -1 Query: 657 KESDRVHTVLHIQHSTWPDHGVPNDSS----TVRKILKRLYYVGKDHPIVAHCSAGIGRT 490 ++ ++V V WP+ G+P + + + K+ G +HPI HCSAG GRT Sbjct: 578 RQEEQVRMVRQFHFHGWPEVGIPAEGKGMIDLIAAVQKQQQQTG-NHPITVHCSAGAGRT 636 Query: 489 GAYITIHNTVERILRGDQAATNLVETVGKFRSQRPGIVQTEEQYKFCYHAIVD 331 G +I + N +ER+ + ++ + V R QRP +VQT EQY+FCY + D Sbjct: 637 GTFIALSNILERVKA--EGLLDVFQAVKSLRLQRPHMVQTLEQYEFCYKVVQD 687
>PTN7_HUMAN (P35236) Tyrosine-protein phosphatase non-receptor type 7 (EC| 3.1.3.48) (Protein-tyrosine phosphatase LC-PTP) (Hematopoietic protein-tyrosine phosphatase) (HEPTP) Length = 360 Score = 77.4 bits (189), Expect = 4e-14 Identities = 44/133 (33%), Positives = 74/133 (55%), Gaps = 5/133 (3%) Frame = -1 Query: 720 IKIVETRQDGELTLRSVKVQHKESDRVHTVLHIQHSTWPDHGVPNDSSTVRKILKRLYY- 544 I+I + ++ E T+R + +Q++E R +V HI S WPDH P + + +++ + Sbjct: 220 IRIQDMKECPEYTVRQLTIQYQEERR--SVKHILFSAWPDHQTPESAGPLLRLVAEVEES 277 Query: 543 ---VGKDHPIVAHCSAGIGRTGAYITIHNTVERI-LRGDQAATNLVETVGKFRSQRPGIV 376 PIV HCSAGIGRTG +I +++ RG+ +++ V + R R G++ Sbjct: 278 PETAAHPGPIVVHCSAGIGRTGCFIATRIGCQQLKARGE---VDILGIVCQLRLDRGGMI 334 Query: 375 QTEEQYKFCYHAI 337 QT EQY+F +H + Sbjct: 335 QTAEQYQFLHHTL 347
>CD45_MOUSE (P06800) Leukocyte common antigen precursor (EC 3.1.3.48) (L-CA)| (Lymphocyte common antigen Ly-5) (CD45 antigen) (T200) Length = 1291 Score = 77.0 bits (188), Expect = 5e-14 Identities = 46/133 (34%), Positives = 71/133 (53%), Gaps = 3/133 (2%) Frame = -1 Query: 720 IKIVETRQDGELTLRSVKVQHKESDRV-HTVLHIQHSTWPDHGVPNDSSTVRKILKRLYY 544 + I + ++ + ++ + V HK+ V HIQ ++WPDHGVP D + K+ +R+ Sbjct: 768 VTINDHKRCPDYIIQKLNVAHKKEKATGREVTHIQFTSWPDHGVPEDPHLLLKLRRRVNA 827 Query: 543 VGK--DHPIVAHCSAGIGRTGAYITIHNTVERILRGDQAATNLVETVGKFRSQRPGIVQT 370 PIV HCSAG+GRTG YI I +E + + ++ V K R QR +VQ Sbjct: 828 FSNFFSGPIVVHCSAGVGRTGTYIGIDAMLEGL--EAEGKVDVYGYVVKLRRQRCLMVQV 885 Query: 369 EEQYKFCYHAIVD 331 E QY + A+V+ Sbjct: 886 EAQYILIHQALVE 898 Score = 54.3 bits (129), Expect = 4e-07 Identities = 34/141 (24%), Positives = 63/141 (44%), Gaps = 11/141 (7%) Frame = -1 Query: 726 LNIKIVETRQDGELTLRSVKVQHKESDRVHTVLHIQHSTWPDHGVPNDSSTVRKILKRL- 550 + +++ +T + TLR+ +++H + TV Q +TW +P + + +++ L Sbjct: 1073 MEVEMKDTNRASAYTLRTFELRHSKRKEPRTVYQYQCTTWKGEELPAEPKDLVSMIQDLK 1132 Query: 549 ----------YYVGKDHPIVAHCSAGIGRTGAYITIHNTVERILRGDQAATNLVETVGKF 400 K I+ HC G +TG + + N +E D ++ + V Sbjct: 1133 QKLPKASPEGMKYHKHASILVHCRDGSQQTGLFCALFNLLESAETED--VVDVFQVVKSL 1190 Query: 399 RSQRPGIVQTEEQYKFCYHAI 337 R RPG+V + EQY+F Y I Sbjct: 1191 RKARPGVVCSYEQYQFLYDII 1211
>PTN2_HUMAN (P17706) Tyrosine-protein phosphatase non-receptor type 2 (EC| 3.1.3.48) (T-cell protein-tyrosine phosphatase) (TCPTP) Length = 415 Score = 77.0 bits (188), Expect = 5e-14 Identities = 41/138 (29%), Positives = 73/138 (52%), Gaps = 4/138 (2%) Frame = -1 Query: 723 NIKIVETRQDGELTLRSVKVQHKESDRVHTVLHIQHSTWPDHGVPNDSSTVRKILKRLYY 544 ++K++ T+ +++++ S T+ H ++TWPD GVP ++ L ++ Sbjct: 142 SVKLLSEDVKSYYTVHLLQLENINSGETRTISHFHYTTWPDFGVPESPASFLNFLFKVRE 201 Query: 543 VGK---DH-PIVAHCSAGIGRTGAYITIHNTVERILRGDQAATNLVETVGKFRSQRPGIV 376 G DH P V HCSAGIGR+G + + + + +GD N+ + + R R G++ Sbjct: 202 SGSLNPDHGPAVIHCSAGIGRSGTFSLVDTCLVLMEKGDD--INIKQVLLNMRKYRMGLI 259 Query: 375 QTEEQYKFCYHAIVDELK 322 QT +Q +F Y AI++ K Sbjct: 260 QTPDQLRFSYMAIIEGAK 277
>PTN9_RAT (Q641Z2) Tyrosine-protein phosphatase non-receptor type 9 (EC| 3.1.3.48) Length = 593 Score = 76.6 bits (187), Expect = 7e-14 Identities = 42/130 (32%), Positives = 72/130 (55%), Gaps = 15/130 (11%) Frame = -1 Query: 675 SVKVQHKESDRVHTVLHIQHSTWPDHGVPNDSSTVRKILK-----RLYYVGK-------- 535 ++++ + E + V H Q +WPD+GVP+ ++++ L+ + VG Sbjct: 446 TLEIHNTEERQKRQVTHFQFLSWPDYGVPSSAASLIDFLRVVRSQQSMAVGSLGARSKGQ 505 Query: 534 --DHPIVAHCSAGIGRTGAYITIHNTVERILRGDQAATNLVETVGKFRSQRPGIVQTEEQ 361 + PIV HCSAGIGRTG + ++ + ++ + N+ +TV + R+QR +QT EQ Sbjct: 506 CPEPPIVVHCSAGIGRTGTFCSLDICLAQL--EELGTLNVFQTVSRMRTQRAFSIQTPEQ 563 Query: 360 YKFCYHAIVD 331 Y FCY AI++ Sbjct: 564 YYFCYKAILE 573
>PTN9_MOUSE (O35239) Tyrosine-protein phosphatase non-receptor type 9 (EC| 3.1.3.48) (Protein-tyrosine phosphatase MEG2) (PTPase-MEG2) Length = 593 Score = 76.6 bits (187), Expect = 7e-14 Identities = 42/130 (32%), Positives = 72/130 (55%), Gaps = 15/130 (11%) Frame = -1 Query: 675 SVKVQHKESDRVHTVLHIQHSTWPDHGVPNDSSTVRKILK-----RLYYVGK-------- 535 ++++ + E + V H Q +WPD+GVP+ ++++ L+ + VG Sbjct: 446 TLEIHNTEERQKRQVTHFQFLSWPDYGVPSSAASLIDFLRVVRNQQSMAVGNLGARSKGQ 505 Query: 534 --DHPIVAHCSAGIGRTGAYITIHNTVERILRGDQAATNLVETVGKFRSQRPGIVQTEEQ 361 + PIV HCSAGIGRTG + ++ + ++ + N+ +TV + R+QR +QT EQ Sbjct: 506 CPEPPIVVHCSAGIGRTGTFCSLDICLAQL--EELGTLNVFQTVSRMRTQRAFSIQTPEQ 563 Query: 360 YKFCYHAIVD 331 Y FCY AI++ Sbjct: 564 YYFCYKAILE 573
>PTN4_HUMAN (P29074) Tyrosine-protein phosphatase non-receptor type 4 (EC| 3.1.3.48) (Protein-tyrosine phosphatase MEG1) (PTPase-MEG1) (MEG) Length = 926 Score = 76.6 bits (187), Expect = 7e-14 Identities = 45/117 (38%), Positives = 65/117 (55%), Gaps = 2/117 (1%) Frame = -1 Query: 678 RSVKVQHKESDRVHTVLHIQHSTWPDHGVPNDSSTVRKIL--KRLYYVGKDHPIVAHCSA 505 R + + ++E + + IQ+ WPDHGVP+DSS + R GK+ P+V HCSA Sbjct: 795 RKMTLFNQEKNESRPLTQIQYIAWPDHGVPDDSSDFLDFVCHVRNKRAGKEEPVVVHCSA 854 Query: 504 GIGRTGAYITIHNTVERILRGDQAATNLVETVGKFRSQRPGIVQTEEQYKFCYHAIV 334 GIGRTG IT+ T ++ +Q L + V R QR ++QT QY+F AI+ Sbjct: 855 GIGRTGVLITM-ETAMCLIECNQPVYPL-DIVRTMRDQRAMMIQTPSQYRFVCEAIL 909
>PTN13_MOUSE (Q64512) Tyrosine-protein phosphatase non-receptor type 13 (EC| 3.1.3.48) (Protein tyrosine phosphatase PTP-BL) (Protein-tyrosine phosphatase RIP) (protein tyrosine phosphatase DPZPTP) (PTP36) Length = 2453 Score = 76.3 bits (186), Expect = 9e-14 Identities = 40/137 (29%), Positives = 69/137 (50%) Frame = -1 Query: 726 LNIKIVETRQDGELTLRSVKVQHKESDRVHTVLHIQHSTWPDHGVPNDSSTVRKILKRLY 547 L + ++ +Q +R + ++ ++ V + H+ + WPDH P+ + + + Sbjct: 2304 LRLALLRMQQLKGFIVRVMALEDIQTGEVRHISHLNFTAWPDHDTPSQPDDLLTFISYMR 2363 Query: 546 YVGKDHPIVAHCSAGIGRTGAYITIHNTVERILRGDQAATNLVETVGKFRSQRPGIVQTE 367 ++ + P++ HCSAGIGR+G I I + I ++ + V R QR G+VQTE Sbjct: 2364 HIRRSGPVITHCSAGIGRSGTLICIDVVLGLI--SQDLEFDISDLVRCMRLQRHGMVQTE 2421 Query: 366 EQYKFCYHAIVDELKDL 316 QY FCY I+ L L Sbjct: 2422 GQYVFCYQVILYVLTHL 2438
>PTPRK_MOUSE (P35822) Receptor-type tyrosine-protein phosphatase kappa precursor| (EC 3.1.3.48) (Protein-tyrosine phosphatase kappa) (R-PTP-kappa) Length = 1457 Score = 75.9 bits (185), Expect = 1e-13 Identities = 43/132 (32%), Positives = 68/132 (51%), Gaps = 2/132 (1%) Frame = -1 Query: 720 IKIVETRQDGELTLRSVKVQHKESDRVHTVLHIQHSTWPDHGVPNDSSTVRKILKRLYYV 541 + VE E +R+ ++ + + + V + WPDHGVP ++ + ++R+ Sbjct: 1029 VTCVEMEPLAEYVVRTFTLERRGYNEIREVKQFHFTGWPDHGVPYHATGLLSFIRRVKLS 1088 Query: 540 GKDH--PIVAHCSAGIGRTGAYITIHNTVERILRGDQAATNLVETVGKFRSQRPGIVQTE 367 PIV HCSAG GRTG YI I ++ R + ++ V RS+R +VQTE Sbjct: 1089 NPPSAGPIVVHCSAGAGRTGCYIVIDIMLDMAER--EGVVDIYNCVKALRSRRINMVQTE 1146 Query: 366 EQYKFCYHAIVD 331 EQY F + AI++ Sbjct: 1147 EQYIFIHDAILE 1158 Score = 47.0 bits (110), Expect = 6e-05 Identities = 33/113 (29%), Positives = 50/113 (44%), Gaps = 9/113 (7%) Frame = -1 Query: 633 VLHIQHSTWPDHG-VPNDSSTVRKILKRLYYVGK--------DHPIVAHCSAGIGRTGAY 481 V Q+ W H VP R LK + V K + + HC G GR+G + Sbjct: 1348 VQQFQYLGWASHREVPGSK---RSFLKLILQVEKWQEECEEGEGRTIIHCLNGGGRSGMF 1404 Query: 480 ITIHNTVERILRGDQAATNLVETVGKFRSQRPGIVQTEEQYKFCYHAIVDELK 322 I VE + R Q ++ V R+ +P +V+ EQY+FCY ++ L+ Sbjct: 1405 CAIGIVVEMVKR--QNVVDVFHAVKTLRNSKPNMVEAPEQYRFCYDVALEYLE 1455
>PTPRK_HUMAN (Q15262) Receptor-type tyrosine-protein phosphatase kappa precursor| (EC 3.1.3.48) (Protein-tyrosine phosphatase kappa) (R-PTP-kappa) Length = 1439 Score = 75.9 bits (185), Expect = 1e-13 Identities = 43/132 (32%), Positives = 68/132 (51%), Gaps = 2/132 (1%) Frame = -1 Query: 720 IKIVETRQDGELTLRSVKVQHKESDRVHTVLHIQHSTWPDHGVPNDSSTVRKILKRLYYV 541 + VE E +R+ ++ + + + V + WPDHGVP ++ + ++R+ Sbjct: 1011 VTCVEMEPLAEYVVRTFTLERRGYNEIREVKQFHFTGWPDHGVPYHATGLLSFIRRVKLS 1070 Query: 540 GKDH--PIVAHCSAGIGRTGAYITIHNTVERILRGDQAATNLVETVGKFRSQRPGIVQTE 367 PIV HCSAG GRTG YI I ++ R + ++ V RS+R +VQTE Sbjct: 1071 NPPSAGPIVVHCSAGAGRTGCYIVIDIMLDMAER--EGVVDIYNCVKALRSRRINMVQTE 1128 Query: 366 EQYKFCYHAIVD 331 EQY F + AI++ Sbjct: 1129 EQYIFIHDAILE 1140 Score = 47.0 bits (110), Expect = 6e-05 Identities = 33/113 (29%), Positives = 50/113 (44%), Gaps = 9/113 (7%) Frame = -1 Query: 633 VLHIQHSTWPDHG-VPNDSSTVRKILKRLYYVGK--------DHPIVAHCSAGIGRTGAY 481 V Q+ W H VP R LK + V K + + HC G GR+G + Sbjct: 1330 VQQFQYLGWASHREVPGSK---RSFLKLILQVEKWQEECEEGEGRTIIHCLNGGGRSGMF 1386 Query: 480 ITIHNTVERILRGDQAATNLVETVGKFRSQRPGIVQTEEQYKFCYHAIVDELK 322 I VE + R Q ++ V R+ +P +V+ EQY+FCY ++ L+ Sbjct: 1387 CAIGIVVEMVKR--QNVVDVFHAVKTLRNSKPNMVEAPEQYRFCYDVALEYLE 1437
>PTPRZ_RAT (Q62656) Receptor-type tyrosine-protein phosphatase zeta precursor| (EC 3.1.3.48) (R-PTP-zeta) (Phosphacan) (3F8 chondroitin sulfate proteoglycan) (3H1 keratan sulfate proteoglycan) Length = 2316 Score = 75.5 bits (184), Expect = 2e-13 Identities = 47/141 (33%), Positives = 76/141 (53%), Gaps = 8/141 (5%) Frame = -1 Query: 723 NIKIVETRQDGELTLRSVKVQH-----KESDRVHTVLHIQHSTWPDHGVPNDSSTVRKIL 559 N++++ TLR+ K++ + S R+ T H ++ WPD GVP S V + Sbjct: 1859 NVQVLAYYTVRNFTLRNTKIKKGSQKGRSSGRLVTQYH--YTQWPDMGVPEYSLPVLAFV 1916 Query: 558 KRLYYVGKDH---PIVAHCSAGIGRTGAYITIHNTVERILRGDQAATNLVETVGKFRSQR 388 ++ K H P+V HCSAG+GRTG YI + + +++I + N+ + RSQR Sbjct: 1917 RKTAQA-KRHAVGPVVVHCSAGVGRTGTYIVLDSMLQQIQH--EGTVNIFGFLKHIRSQR 1973 Query: 387 PGIVQTEEQYKFCYHAIVDEL 325 +VQTEEQY F + +V+ + Sbjct: 1974 NYLVQTEEQYVFIHDTLVEAI 1994 Score = 35.8 bits (81), Expect = 0.14 Identities = 22/119 (18%), Positives = 50/119 (42%) Frame = -1 Query: 690 ELTLRSVKVQHKESDRVHTVLHIQHSTWPDHGVPNDSSTVRKILKRLYYVGKDHPIVAHC 511 +L ++ ++ + D V V H Q WP+ P + + + +D P++ H Sbjct: 2165 KLIVQDFILEATQDDYVLEVRHFQCPKWPNPDSPISKTFELISIIKEEAANRDGPMIVHD 2224 Query: 510 SAGIGRTGAYITIHNTVERILRGDQAATNLVETVGKFRSQRPGIVQTEEQYKFCYHAIV 334 G G + + + ++ + + + ++ + RPG+ EQY+F Y ++ Sbjct: 2225 EHGGVTAGTFCALTTLMHQLEK--ENSMDVYQVAKMINLMRPGVFTDIEQYQFLYKVVL 2281
>PTPRM_HUMAN (P28827) Receptor-type tyrosine-protein phosphatase mu precursor (EC| 3.1.3.48) (Protein-tyrosine phosphatase mu) (R-PTP-mu) Length = 1452 Score = 75.5 bits (184), Expect = 2e-13 Identities = 40/134 (29%), Positives = 71/134 (52%), Gaps = 2/134 (1%) Frame = -1 Query: 726 LNIKIVETRQDGELTLRSVKVQHKESDRVHTVLHIQHSTWPDHGVPNDSSTVRKILKRLY 547 + + ++ET E +R+ V+ + + + + WPDHGVP ++ + ++++ Sbjct: 1022 IKVTLIETELLAEYVIRTFAVEKRGVHEIREIRQFHFTGWPDHGVPYHATGLLGFVRQVK 1081 Query: 546 YVGKDH--PIVAHCSAGIGRTGAYITIHNTVERILRGDQAATNLVETVGKFRSQRPGIVQ 373 P+V HCSAG GRTG +I I ++ R + ++ V + RS+R +VQ Sbjct: 1082 SKSPPSAGPLVVHCSAGAGRTGCFIVIDIMLDMAER--EGVVDIYNCVRELRSRRVNMVQ 1139 Query: 372 TEEQYKFCYHAIVD 331 TEEQY F + AI++ Sbjct: 1140 TEEQYVFIHDAILE 1153 Score = 49.3 bits (116), Expect = 1e-05 Identities = 33/142 (23%), Positives = 62/142 (43%), Gaps = 8/142 (5%) Frame = -1 Query: 726 LNIKIVETRQDGELTLRSVKVQH--KESDRVHTVLHIQHSTWPDH-GVPNDSSTVRKILK 556 + ++ V + ++ R ++ + + D V Q WP + P + K+++ Sbjct: 1310 IQVEFVSADLEEDIISRIFRIYNAARPQDGYRMVQQFQFLGWPMYRDTPVSKRSFLKLIR 1369 Query: 555 RL-----YYVGKDHPIVAHCSAGIGRTGAYITIHNTVERILRGDQAATNLVETVGKFRSQ 391 ++ Y G + P V HC G GR+G + I E + Q ++ V R+ Sbjct: 1370 QVDKWQEEYNGGEGPTVVHCLNGGGRSGTFCAISIVCEMLRH--QRTVDVFHAVKTLRNN 1427 Query: 390 RPGIVQTEEQYKFCYHAIVDEL 325 +P +V +QYKFCY ++ L Sbjct: 1428 KPNMVDLLDQYKFCYEVALEYL 1449
>PTN9_HUMAN (P43378) Tyrosine-protein phosphatase non-receptor type 9 (EC| 3.1.3.48) (Protein-tyrosine phosphatase MEG2) (PTPase-MEG2) Length = 593 Score = 75.5 bits (184), Expect = 2e-13 Identities = 41/130 (31%), Positives = 70/130 (53%), Gaps = 15/130 (11%) Frame = -1 Query: 675 SVKVQHKESDRVHTVLHIQHSTWPDHGVPNDSSTVRKILK---------------RLYYV 541 ++++ + E + V H Q +WPD+GVP+ ++++ L+ R Sbjct: 446 TLEIHNTEERQKRQVTHFQFLSWPDYGVPSSAASLIDFLRVVRNQQSLAVSNMGARSKGQ 505 Query: 540 GKDHPIVAHCSAGIGRTGAYITIHNTVERILRGDQAATNLVETVGKFRSQRPGIVQTEEQ 361 + PIV HCSAGIGRTG + ++ + ++ + N+ +TV + R+QR +QT EQ Sbjct: 506 CPEPPIVVHCSAGIGRTGTFCSLDICLAQL--EELGTLNVFQTVSRMRTQRAFSIQTPEQ 563 Query: 360 YKFCYHAIVD 331 Y FCY AI++ Sbjct: 564 YYFCYKAILE 573
>CD45_RAT (P04157) Leukocyte common antigen variant 4 precursor (EC 3.1.3.48)| (L-CA) (CD45 antigen) (T200) (Fragment) Length = 1255 Score = 75.1 bits (183), Expect = 2e-13 Identities = 44/133 (33%), Positives = 70/133 (52%), Gaps = 3/133 (2%) Frame = -1 Query: 720 IKIVETRQDGELTLRSVKVQHKESDRV-HTVLHIQHSTWPDHGVPNDSSTVRKILKRLYY 544 + I + ++ + ++ + + HK+ V HIQ ++WPDHGVP D + K+ +R+ Sbjct: 732 VTINDHKRCPDYIIQKLSIAHKKEKATGREVTHIQFTSWPDHGVPEDPHLLLKLRRRVNA 791 Query: 543 VGK--DHPIVAHCSAGIGRTGAYITIHNTVERILRGDQAATNLVETVGKFRSQRPGIVQT 370 PIV HCSAG+GRTG YI I +E + + ++ V R QR +VQ Sbjct: 792 FSNFFSGPIVVHCSAGVGRTGTYIGIDAMLESL--EAEGKVDVYGYVVNLRRQRCLMVQV 849 Query: 369 EEQYKFCYHAIVD 331 E QY + A+V+ Sbjct: 850 EAQYILIHQALVE 862 Score = 52.4 bits (124), Expect = 1e-06 Identities = 34/138 (24%), Positives = 63/138 (45%), Gaps = 11/138 (7%) Frame = -1 Query: 726 LNIKIVETRQDGELTLRSVKVQHKESDRVHTVLHIQHSTWPDHGVPNDS----STVRKIL 559 + + + +T + LR+ +++H + TV Q +TW +P + + ++ I Sbjct: 1037 MEVMLKDTNKSSAYILRAFELRHSKRKEPRTVYQYQCTTWKGEELPAEPKDLVTLIQNIK 1096 Query: 558 KRLYYVG-------KDHPIVAHCSAGIGRTGAYITIHNTVERILRGDQAATNLVETVGKF 400 ++L G K I+ HC G +TG + + N +E D ++ + V Sbjct: 1097 QKLPKSGSEGMKYHKHASILVHCRDGSQQTGLFCALFNLLESAETED--VVDVFQVVKSL 1154 Query: 399 RSQRPGIVQTEEQYKFCY 346 R RPG+V + EQY+F Y Sbjct: 1155 RKARPGMVGSFEQYQFLY 1172
>PTN1_CHICK (O13016) Tyrosine-protein phosphatase non-receptor type 1 (EC| 3.1.3.48) (Protein-tyrosine phosphatase 1B) (PTP-1B) (CPTP1) Length = 434 Score = 75.1 bits (183), Expect = 2e-13 Identities = 39/141 (27%), Positives = 77/141 (54%), Gaps = 7/141 (4%) Frame = -1 Query: 723 NIKIVETRQD--GELTLRSVKVQHKESDRVHTVLHIQHSTWPDHGVPNDSSTVRKILKRL 550 N+K+ +D T+R +++++ + +LH ++TWPD GVP ++ L ++ Sbjct: 139 NLKLTLISEDIKSYYTVRQLELENLTTQETREILHFHYTTWPDFGVPESPASFLNFLFKV 198 Query: 549 YYVGKDH----PIVAHCSAGIGRTGAYITIHNTVERI-LRGDQAATNLVETVGKFRSQRP 385 G + P+V HCSAGIGR+G + + + + R D ++ ++ + + + R R Sbjct: 199 RESGSLNPEYGPVVVHCSAGIGRSGTFCLVDTCLLLMDKRKDPSSVDVKQVLLEMRKYRM 258 Query: 384 GIVQTEEQYKFCYHAIVDELK 322 G++QT +Q +F Y A+++ K Sbjct: 259 GLIQTADQLRFSYLAVIEGAK 279
>PTN2_RAT (P35233) Tyrosine-protein phosphatase non-receptor type 2 (EC| 3.1.3.48) (Protein-tyrosine phosphatase PTP-S) Length = 363 Score = 75.1 bits (183), Expect = 2e-13 Identities = 40/138 (28%), Positives = 73/138 (52%), Gaps = 4/138 (2%) Frame = -1 Query: 723 NIKIVETRQDGELTLRSVKVQHKESDRVHTVLHIQHSTWPDHGVPNDSSTVRKILKRLYY 544 ++K++ T+ +++++ S T+ H ++TWPD GVP ++ L ++ Sbjct: 142 SVKLLSEDVKSYYTVHLLQLENINSGETRTISHFHYTTWPDFGVPESPASFLNFLFKVRE 201 Query: 543 VGK---DH-PIVAHCSAGIGRTGAYITIHNTVERILRGDQAATNLVETVGKFRSQRPGIV 376 G DH P V HCSAGIGR+G + + + + +G+ N+ + + R R G++ Sbjct: 202 SGSLNPDHGPAVIHCSAGIGRSGTFSLVDTCLVLMEKGED--VNVKQILLSMRKYRMGLI 259 Query: 375 QTEEQYKFCYHAIVDELK 322 QT +Q +F Y AI++ K Sbjct: 260 QTPDQLRFSYMAIIEGAK 277
>PTPRM_MOUSE (P28828) Receptor-type tyrosine-protein phosphatase mu precursor (EC| 3.1.3.48) (Protein-tyrosine phosphatase mu) (R-PTP-mu) Length = 1452 Score = 75.1 bits (183), Expect = 2e-13 Identities = 39/134 (29%), Positives = 72/134 (53%), Gaps = 2/134 (1%) Frame = -1 Query: 726 LNIKIVETRQDGELTLRSVKVQHKESDRVHTVLHIQHSTWPDHGVPNDSSTVRKILKRLY 547 + + +++T E +R+ V+ + + + + WPDHGVP ++ + ++++ Sbjct: 1022 IKVTLIDTELLAEYVIRTFAVEKRGIHEIREIRQFHFTGWPDHGVPYHATGLLGFVRQVK 1081 Query: 546 YVGKDH--PIVAHCSAGIGRTGAYITIHNTVERILRGDQAATNLVETVGKFRSQRPGIVQ 373 + P+V HCSAG GRTG +I I ++ R + ++ V + RS+R +VQ Sbjct: 1082 SKSPPNAGPLVVHCSAGAGRTGCFIVIDIMLDMAER--EGVVDIYNCVRELRSRRVNMVQ 1139 Query: 372 TEEQYKFCYHAIVD 331 TEEQY F + AI++ Sbjct: 1140 TEEQYVFIHDAILE 1153 Score = 48.5 bits (114), Expect = 2e-05 Identities = 33/142 (23%), Positives = 62/142 (43%), Gaps = 8/142 (5%) Frame = -1 Query: 726 LNIKIVETRQDGELTLRSVKVQH--KESDRVHTVLHIQHSTWPDH-GVPNDSSTVRKILK 556 + ++ V + ++ R ++ + + D V Q WP + P + K+++ Sbjct: 1310 IQVEFVSADLEEDIISRIFRIYNASRPQDGHRMVQQFQFLGWPMYRDTPVSKRSFLKLIR 1369 Query: 555 RL-----YYVGKDHPIVAHCSAGIGRTGAYITIHNTVERILRGDQAATNLVETVGKFRSQ 391 ++ Y G + P V HC G GR+G + I E + Q ++ V R+ Sbjct: 1370 QVDKWQEEYNGGEGPTVVHCLNGGGRSGTFCAISIVCEMLRH--QRTVDVFHAVKTLRNN 1427 Query: 390 RPGIVQTEEQYKFCYHAIVDEL 325 +P +V +QYKFCY ++ L Sbjct: 1428 KPNMVDLLDQYKFCYEVALEYL 1449
>PTPRJ_MOUSE (Q64455) Receptor-type tyrosine-protein phosphatase eta precursor (EC| 3.1.3.48) (Protein-tyrosine phosphatase eta) (R-PTP-eta) (HPTP beta-like tyrosine phosphatase) (Protein-tyrosine phosphatase receptor type J) (Susceptibility to colon cance Length = 1238 Score = 75.1 bits (183), Expect = 2e-13 Identities = 41/130 (31%), Positives = 70/130 (53%), Gaps = 7/130 (5%) Frame = -1 Query: 690 ELTLRSVKVQHKESDRVHTVLHIQHSTWPDHGVPNDSST-------VRKILKRLYYVGKD 532 E T+R V++ ++ H + ++WPDHGVP+ + VR +K+ + + Sbjct: 1077 EWTIRDFVVKNMQNSESHPLRQFHFTSWPDHGVPDTTDLLINFRYLVRDYMKQ---IPPE 1133 Query: 531 HPIVAHCSAGIGRTGAYITIHNTVERILRGDQAATNLVETVGKFRSQRPGIVQTEEQYKF 352 PI+ HCSAG+GRTG +I I + +I ++ ++ V R RP +VQTE+QY F Sbjct: 1134 SPILVHCSAGVGRTGTFIAIDRLIYQI--ENENTVDVYGIVYDLRMHRPLMVQTEDQYVF 1191 Query: 351 CYHAIVDELK 322 ++D ++ Sbjct: 1192 LNQCVLDIIR 1201
>PTN1_RAT (P20417) Tyrosine-protein phosphatase non-receptor type 1 (EC| 3.1.3.48) (Protein-tyrosine phosphatase 1B) (PTP-1B) Length = 432 Score = 74.7 bits (182), Expect = 3e-13 Identities = 42/147 (28%), Positives = 82/147 (55%), Gaps = 7/147 (4%) Frame = -1 Query: 723 NIKIVETRQDGE--LTLRSVKVQHKESDRVHTVLHIQHSTWPDHGVPNDSSTVRKILKRL 550 N+K+ +D + T+R +++++ + +LH ++TWPD GVP ++ L ++ Sbjct: 139 NLKLTLISEDVKSYYTVRQLELENLATQEAREILHFHYTTWPDFGVPESPASFLNFLFKV 198 Query: 549 YYVGK---DH-PIVAHCSAGIGRTGAYITIHNTVERI-LRGDQAATNLVETVGKFRSQRP 385 G +H PIV HCSAGIGR+G + + + R D ++ ++ + + + R R Sbjct: 199 RESGSLSPEHGPIVVHCSAGIGRSGTFCLADTCLLLMDKRKDPSSVDIKKVLLEMRRFRM 258 Query: 384 GIVQTEEQYKFCYHAIVDELKDLIRNS 304 G++QT +Q +F Y A+++ K ++ +S Sbjct: 259 GLIQTADQLRFSYLAVIEGAKFIMGDS 285
>PTN1_HUMAN (P18031) Tyrosine-protein phosphatase non-receptor type 1 (EC| 3.1.3.48) (Protein-tyrosine phosphatase 1B) (PTP-1B) Length = 435 Score = 74.7 bits (182), Expect = 3e-13 Identities = 41/147 (27%), Positives = 81/147 (55%), Gaps = 7/147 (4%) Frame = -1 Query: 723 NIKIVETRQD--GELTLRSVKVQHKESDRVHTVLHIQHSTWPDHGVPNDSSTVRKILKRL 550 N+K+ +D T+R +++++ + +LH ++TWPD GVP ++ L ++ Sbjct: 139 NLKLTLISEDIKSYYTVRQLELENLTTQETREILHFHYTTWPDFGVPESPASFLNFLFKV 198 Query: 549 YYVGK---DH-PIVAHCSAGIGRTGAYITIHNTVERI-LRGDQAATNLVETVGKFRSQRP 385 G +H P+V HCSAGIGR+G + + + R D ++ ++ + + + R R Sbjct: 199 RESGSLSPEHGPVVVHCSAGIGRSGTFCLADTCLLLMDKRKDPSSVDIKKVLLEMRKFRM 258 Query: 384 GIVQTEEQYKFCYHAIVDELKDLIRNS 304 G++QT +Q +F Y A+++ K ++ +S Sbjct: 259 GLIQTADQLRFSYLAVIEGAKFIMGDS 285
>PTPRJ_HUMAN (Q12913) Receptor-type tyrosine-protein phosphatase eta precursor (EC| 3.1.3.48) (Protein-tyrosine phosphatase eta) (R-PTP-eta) (HPTP eta) (Protein-tyrosine phosphatase receptor type J) (Density-enhanced phosphatase 1) (DEP-1) (CD148 antigen) Length = 1337 Score = 74.3 bits (181), Expect = 4e-13 Identities = 43/138 (31%), Positives = 73/138 (52%), Gaps = 8/138 (5%) Frame = -1 Query: 690 ELTLRSVKVQHKESDRVHTVLHIQHSTWPDHGVPNDSSTVRKILKRLYYVGKDH------ 529 E T+R V++ ++ H + ++WPDHGVP+ + +L Y+ +D+ Sbjct: 1176 EWTIRDFTVKNIQTSESHPLRQFHFTSWPDHGVPDTTD----LLINFRYLVRDYMKQSPP 1231 Query: 528 --PIVAHCSAGIGRTGAYITIHNTVERILRGDQAATNLVETVGKFRSQRPGIVQTEEQYK 355 PI+ HCSAG+GRTG +I I + +I ++ ++ V R RP +VQTE+QY Sbjct: 1232 ESPILVHCSAGVGRTGTFIAIDRLIYQI--ENENTVDVYGIVYDLRMHRPLMVQTEDQYV 1289 Query: 354 FCYHAIVDELKDLIRNSK 301 F ++ D++R+ K Sbjct: 1290 FLNQCVL----DIVRSQK 1303
>PTPRG_MOUSE (Q05909) Receptor-type tyrosine-protein phosphatase gamma precursor| (EC 3.1.3.48) (Protein-tyrosine phosphatase gamma) (R-PTP-gamma) Length = 1442 Score = 74.3 bits (181), Expect = 4e-13 Identities = 43/129 (33%), Positives = 72/129 (55%), Gaps = 8/129 (6%) Frame = -1 Query: 687 LTLRSVKVQH------KESDRVHTVLHIQHSTWPDHGVPNDSSTVRKILKRLYYVGKDH- 529 L++R+ KV+ K TV+ ++ WPD GVP + V ++R Sbjct: 991 LSVRNTKVKKGQKGNPKGRQNERTVIQYHYTQWPDMGVPEYALPVLTFVRRSSAARMPDM 1050 Query: 528 -PIVAHCSAGIGRTGAYITIHNTVERILRGDQAATNLVETVGKFRSQRPGIVQTEEQYKF 352 P++ HCSAG+GRTG YI I + +++I D++ N++ + R+QR +VQTEEQY F Sbjct: 1051 GPVLVHCSAGVGRTGTYIVIDSMLQQI--KDKSTVNVLGFLKHIRTQRNYLVQTEEQYIF 1108 Query: 351 CYHAIVDEL 325 + A+++ + Sbjct: 1109 IHDALLEAI 1117 Score = 37.0 bits (84), Expect = 0.062 Identities = 24/119 (20%), Positives = 50/119 (42%) Frame = -1 Query: 690 ELTLRSVKVQHKESDRVHTVLHIQHSTWPDHGVPNDSSTVRKILKRLYYVGKDHPIVAHC 511 ++ + ++ + D V V H Q WP+ P S+ + + + +D P + H Sbjct: 1289 QIIIHDFILEATQDDYVLEVRHFQCPKWPNPDAPISSTFELINVIKEEALTRDGPTIVHD 1348 Query: 510 SAGIGRTGAYITIHNTVERILRGDQAATNLVETVGKFRSQRPGIVQTEEQYKFCYHAIV 334 G G + +++ ++ A ++ + RPG+ EQY+F Y A++ Sbjct: 1349 EYGAVSAGMLCALTTLSQQL--ENENAVDVFQVAKMINLMRPGVFTDIEQYQFVYKAML 1405
>PTN22_HUMAN (Q9Y2R2) Tyrosine-protein phosphatase non-receptor type 22 (EC| 3.1.3.48) (Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP) (Lymphoid phosphatase) (LyP) Length = 807 Score = 73.9 bits (180), Expect = 5e-13 Identities = 45/141 (31%), Positives = 74/141 (52%), Gaps = 6/141 (4%) Frame = -1 Query: 702 RQDGELTLRSVKVQHKESDRVHTVLHIQHSTWPDHGVPNDSSTVRKIL--KRLYYVGKDH 529 ++ + +R++KV+ R T+ + WPDH VP+ + +++ R Y Sbjct: 164 KRKSDYIIRTLKVKFNSETR--TIYQFHYKNWPDHDVPSSIDPILELIWDVRCYQEDDSV 221 Query: 528 PIVAHCSAGIGRTGAYITIHNTVERILRGDQAAT-NLVETVGKFRSQRPGIVQTEEQYKF 352 PI HCSAG GRTG I T + G ++ + + R+QRP +VQT+EQY+ Sbjct: 222 PICIHCSAGCGRTGVICAIDYTWMLLKDGIIPENFSVFSLIREMRTQRPSLVQTQEQYEL 281 Query: 351 CYHAIVDELK---DLIRNSKH 298 Y+A+++ K D+IR+ KH Sbjct: 282 VYNAVLELFKRQMDVIRD-KH 301
>PTN1_MOUSE (P35821) Tyrosine-protein phosphatase non-receptor type 1 (EC| 3.1.3.48) (Protein-tyrosine phosphatase 1B) (PTP-1B) (Protein-protein-tyrosine phosphatase HA2) (PTP-HA2) Length = 432 Score = 73.9 bits (180), Expect = 5e-13 Identities = 40/146 (27%), Positives = 79/146 (54%), Gaps = 5/146 (3%) Frame = -1 Query: 726 LNIKIVETRQDGELTLRSVKVQHKESDRVHTVLHIQHSTWPDHGVPNDSSTVRKILKRLY 547 L + ++ T+R +++++ + +LH ++TWPD GVP ++ L ++ Sbjct: 140 LKLTLISEDVKSYYTVRQLELENLTTKETREILHFHYTTWPDFGVPESPASFLNFLFKVR 199 Query: 546 YVGK---DH-PIVAHCSAGIGRTGAYITIHNTVERI-LRGDQAATNLVETVGKFRSQRPG 382 G +H PIV HCSAGIGR+G + + + R D ++ ++ + + + R R G Sbjct: 200 ESGSLSLEHGPIVVHCSAGIGRSGTFCLADTCLLLMDKRKDPSSVDIKKVLLEMRRFRMG 259 Query: 381 IVQTEEQYKFCYHAIVDELKDLIRNS 304 ++QT +Q +F Y A+++ K ++ +S Sbjct: 260 LIQTADQLRFSYLAVIEGAKFIMGDS 285
>PTPRV_RAT (Q64612) Receptor-type tyrosine-protein phosphatase V precursor (EC| 3.1.3.48) (Embryonic stem cell protein-tyrosine phosphatase) (ES cell phosphatase) (Osteotesticular protein-tyrosine phosphatase) (OST-PTP) Length = 1711 Score = 73.6 bits (179), Expect = 6e-13 Identities = 38/138 (27%), Positives = 72/138 (52%), Gaps = 4/138 (2%) Frame = -1 Query: 726 LNIKIVETRQDGELTLRSVKVQHKESDRVHTVLHIQHSTWPDHGVPNDSST----VRKIL 559 + I ++ + E T R ++QH + V +Q +TWPDH VP S+ V + Sbjct: 1275 ITIHLLAEEPEDEWTRREFQLQHGTEQKQRRVKQLQFTTWPDHSVPEAPSSLLAFVELVQ 1334 Query: 558 KRLYYVGKDHPIVAHCSAGIGRTGAYITIHNTVERILRGDQAATNLVETVGKFRSQRPGI 379 +++ PI+ HCSAG+GRTG ++ + + ++ ++ ++ TV R RP + Sbjct: 1335 EQVQATQGKGPILVHCSAGVGRTGTFVALLRLLRQL--EEEKVADVFNTVYILRLHRPLM 1392 Query: 378 VQTEEQYKFCYHAIVDEL 325 +QT QY F + +++++ Sbjct: 1393 IQTLSQYIFLHSCLLNKI 1410
>PTN2_MOUSE (Q06180) Tyrosine-protein phosphatase non-receptor type 2 (EC| 3.1.3.48) (Protein-tyrosine phosphatase PTP-2) (MPTP) Length = 406 Score = 73.6 bits (179), Expect = 6e-13 Identities = 39/138 (28%), Positives = 73/138 (52%), Gaps = 4/138 (2%) Frame = -1 Query: 723 NIKIVETRQDGELTLRSVKVQHKESDRVHTVLHIQHSTWPDHGVPNDSSTVRKILKRLYY 544 ++K++ T+ +++++ + T+ H ++TWPD GVP ++ L ++ Sbjct: 142 SVKLLSEDVKSYYTVHLLQLENINTGETRTISHFHYTTWPDFGVPESPASFLNFLFKVRE 201 Query: 543 VG---KDH-PIVAHCSAGIGRTGAYITIHNTVERILRGDQAATNLVETVGKFRSQRPGIV 376 G DH P V HCSAGIGR+G + + + + +G+ N+ + + R R G++ Sbjct: 202 SGCLTPDHGPAVIHCSAGIGRSGTFSLVDTCLVLMEKGED--VNVKQLLLNMRKYRMGLI 259 Query: 375 QTEEQYKFCYHAIVDELK 322 QT +Q +F Y AI++ K Sbjct: 260 QTPDQLRFSYMAIIEGAK 277
>PTPRN_MOUSE (Q60673) Receptor-type tyrosine-protein phosphatase-like N precursor| (R-PTP-N) (PTP IA-2) Length = 979 Score = 73.6 bits (179), Expect = 6e-13 Identities = 35/129 (27%), Positives = 71/129 (55%), Gaps = 2/129 (1%) Frame = -1 Query: 690 ELTLRSVKVQHKESDRVHTVLHIQHSTWPDHGVPNDSSTVRKILKRLY--YVGKDHPIVA 517 + +RS +++ ++ T+ +WP G P + + +++ Y G+ PI+ Sbjct: 848 DFLVRSFYLKNLQTQETRTLTQFHFLSWPAEGTPASTRPLLDFRRKVNKCYRGRSCPIIV 907 Query: 516 HCSAGIGRTGAYITIHNTVERILRGDQAATNLVETVGKFRSQRPGIVQTEEQYKFCYHAI 337 HCS G GRTG YI I + R+ +G + ++ T+ R QRPG+V++++Q++F A+ Sbjct: 908 HCSDGAGRTGTYILIDMVLNRMAKGVK-EIDIAATLEHVRDQRPGLVRSKDQFEFALTAV 966 Query: 336 VDELKDLIR 310 +E+ +++ Sbjct: 967 AEEVNAILK 975
>PTPRN_HUMAN (Q16849) Receptor-type tyrosine-protein phosphatase-like N precursor| (R-PTP-N) (PTP IA-2) (Islet cell antigen 512) (ICA 512) (Islet cell autoantigen 3) Length = 979 Score = 73.6 bits (179), Expect = 6e-13 Identities = 35/129 (27%), Positives = 71/129 (55%), Gaps = 2/129 (1%) Frame = -1 Query: 690 ELTLRSVKVQHKESDRVHTVLHIQHSTWPDHGVPNDSSTVRKILKRLY--YVGKDHPIVA 517 + +RS +++ ++ T+ +WP G P + + +++ Y G+ PI+ Sbjct: 848 DFLVRSFYLKNVQTQETRTLTQFHFLSWPAEGTPASTRPLLDFRRKVNKCYRGRSCPIIV 907 Query: 516 HCSAGIGRTGAYITIHNTVERILRGDQAATNLVETVGKFRSQRPGIVQTEEQYKFCYHAI 337 HCS G GRTG YI I + R+ +G + ++ T+ R QRPG+V++++Q++F A+ Sbjct: 908 HCSDGAGRTGTYILIDMVLNRMAKGVK-EIDIAATLEHVRDQRPGLVRSKDQFEFALTAV 966 Query: 336 VDELKDLIR 310 +E+ +++ Sbjct: 967 AEEVNAILK 975
>PTPRN_BOVIN (P56722) Receptor-type tyrosine-protein phosphatase-like N precursor| (R-PTP-N) (Islet cell autoantigen 512) (ICA512) Length = 979 Score = 73.6 bits (179), Expect = 6e-13 Identities = 35/129 (27%), Positives = 71/129 (55%), Gaps = 2/129 (1%) Frame = -1 Query: 690 ELTLRSVKVQHKESDRVHTVLHIQHSTWPDHGVPNDSSTVRKILKRLY--YVGKDHPIVA 517 + +RS +++ ++ T+ +WP G P + + +++ Y G+ PI+ Sbjct: 848 DFLVRSFYLKNVQTQETRTLTQFHFLSWPAEGTPASTRPLLDFRRKVNKCYRGRSCPIIV 907 Query: 516 HCSAGIGRTGAYITIHNTVERILRGDQAATNLVETVGKFRSQRPGIVQTEEQYKFCYHAI 337 HCS G GRTG YI I + R+ +G + ++ T+ R QRPG+V++++Q++F A+ Sbjct: 908 HCSDGAGRTGTYILIDMVLNRMAKGVK-EIDIAATLEHVRDQRPGLVRSKDQFEFALTAV 966 Query: 336 VDELKDLIR 310 +E+ +++ Sbjct: 967 AEEVNAILK 975
>PTPRN_RAT (Q63259) Receptor-type tyrosine-protein phosphatase-like N precursor| (R-PTP-N) (105 kDa islet cell antigen) (ICA105) (PTP IA-2) (PTPLP) (Brain-enriched membrane-associated protein tyrosine phosphatase) (BEM-3) Length = 983 Score = 73.6 bits (179), Expect = 6e-13 Identities = 35/129 (27%), Positives = 71/129 (55%), Gaps = 2/129 (1%) Frame = -1 Query: 690 ELTLRSVKVQHKESDRVHTVLHIQHSTWPDHGVPNDSSTVRKILKRLY--YVGKDHPIVA 517 + +RS +++ ++ T+ +WP G P + + +++ Y G+ PI+ Sbjct: 852 DFLVRSFYLKNVQTQETRTLTQFHFLSWPAEGTPASTRPLLDFRRKVNKCYRGRSCPIIV 911 Query: 516 HCSAGIGRTGAYITIHNTVERILRGDQAATNLVETVGKFRSQRPGIVQTEEQYKFCYHAI 337 HCS G GRTG YI I + R+ +G + ++ T+ R QRPG+V++++Q++F A+ Sbjct: 912 HCSDGAGRTGTYILIDMVLNRMAKGVK-EIDIAATLEHVRDQRPGLVRSKDQFEFALTAV 970 Query: 336 VDELKDLIR 310 +E+ +++ Sbjct: 971 AEEVNAILK 979
>PTPRG_HUMAN (P23470) Receptor-type tyrosine-protein phosphatase gamma precursor| (EC 3.1.3.48) (Protein-tyrosine phosphatase gamma) (R-PTP-gamma) Length = 1445 Score = 73.2 bits (178), Expect = 8e-13 Identities = 39/113 (34%), Positives = 70/113 (61%), Gaps = 2/113 (1%) Frame = -1 Query: 657 KESDRVHTVLHIQHSTWPDHGVPNDSSTVRKILKR--LYYVGKDHPIVAHCSAGIGRTGA 484 ++++RV V+ ++ WPD GVP + V ++R + + P++ HCSAG+GRTG Sbjct: 1012 RQNERV--VIQYHYTQWPDMGVPEYALPVLTFVRRSSAARMPETGPVLVHCSAGVGRTGT 1069 Query: 483 YITIHNTVERILRGDQAATNLVETVGKFRSQRPGIVQTEEQYKFCYHAIVDEL 325 YI I + +++I D++ N++ + R+QR +VQTEEQY F + A+++ + Sbjct: 1070 YIVIDSMLQQI--KDKSTVNVLGFLKHIRTQRNYLVQTEEQYIFIHDALLEAI 1120 Score = 36.2 bits (82), Expect = 0.11 Identities = 24/117 (20%), Positives = 48/117 (41%) Frame = -1 Query: 690 ELTLRSVKVQHKESDRVHTVLHIQHSTWPDHGVPNDSSTVRKILKRLYYVGKDHPIVAHC 511 ++ + ++ + D V V H Q WP+ P S+ + + + +D P + H Sbjct: 1292 QIIIHDFILEATQDDYVLEVRHFQCPKWPNPDAPISSTFELINVIKEEALTRDGPTIVHD 1351 Query: 510 SAGIGRTGAYITIHNTVERILRGDQAATNLVETVGKFRSQRPGIVQTEEQYKFCYHA 340 G G + +++ ++ A ++ + RPG+ EQY+F Y A Sbjct: 1352 EYGAVSAGMLCALTTLSQQL--ENENAVDVFQVAKMINLMRPGVFTDIEQYQFIYKA 1406
>PTN23_HUMAN (Q9H3S7) Tyrosine-protein phosphatase non-receptor type 23 (EC| 3.1.3.48) (His-domain-containing protein tyrosine phosphatase) (HD-PTP) (Protein tyrosine phosphatase TD14) (PTP-TD14) Length = 1636 Score = 73.2 bits (178), Expect = 8e-13 Identities = 36/144 (25%), Positives = 79/144 (54%), Gaps = 5/144 (3%) Frame = -1 Query: 726 LNIKIVETRQDGELTLRSVKVQHKESDRVHTVLHIQHSTWPDHGVPNDSSTVRKILKRLY 547 L++ + R R + +Q ++ +++H+ TWP+ G+P+ S + + ++ ++ Sbjct: 1316 LSLALSSVRSTETHVERVLSLQFRDQSLKRSLVHLHFPTWPELGLPDSPSNLLRFIQEVH 1375 Query: 546 --YVGK---DHPIVAHCSAGIGRTGAYITIHNTVERILRGDQAATNLVETVGKFRSQRPG 382 Y+ + PI+ HCS+G+GRTGA+ ++ V+ + G+ L + V + R QR Sbjct: 1376 AHYLHQRPLHTPIIVHCSSGVGRTGAFALLYAAVQEVEAGN-GIPELPQLVRRMRQQRKH 1434 Query: 381 IVQTEEQYKFCYHAIVDELKDLIR 310 ++Q + +FCY A+V ++ +++ Sbjct: 1435 MLQEKLHLRFCYEAVVRHVEQVLQ 1458
>PTPRR_HUMAN (Q15256) Receptor-type tyrosine-protein phosphatase R precursor (EC| 3.1.3.48) (Protein-tyrosine phosphatase PCPTP1) (NC-PTPCOM1) (Ch-1PTPase) Length = 657 Score = 72.8 bits (177), Expect = 1e-12 Identities = 39/135 (28%), Positives = 73/135 (54%), Gaps = 5/135 (3%) Frame = -1 Query: 726 LNIKIVETRQDGELTLRSVKVQHKESDRVHTVLHIQHSTWPDHGVPNDSSTVRKIL---- 559 + + ++ + T+R++ + K+ V H +++WPDH P+ + + +++ Sbjct: 515 VEVLVISVNECDNYTIRNLVL--KQGSHTQHVKHYWYTSWPDHKTPDSAQPLLQLMLDVE 572 Query: 558 -KRLYYVGKDHPIVAHCSAGIGRTGAYITIHNTVERILRGDQAATNLVETVGKFRSQRPG 382 RL G+ P+V HCSAGIGRTG +I +++ ++ + + V + R R G Sbjct: 573 EDRLASQGRG-PVVVHCSAGIGRTGCFIATSIGCQQL--KEEGVVDALSIVCQLRMDRGG 629 Query: 381 IVQTEEQYKFCYHAI 337 +VQT EQY+F +HA+ Sbjct: 630 MVQTSEQYEFVHHAL 644
>PTP61_DROME (Q9W0G1) Tyrosine-protein phosphatase non-receptor type 61F (EC| 3.1.3.48) (dPTP61F) Length = 548 Score = 72.8 bits (177), Expect = 1e-12 Identities = 42/141 (29%), Positives = 73/141 (51%), Gaps = 4/141 (2%) Frame = -1 Query: 726 LNIKIVETRQDGELTLRSVKVQHKESDRVHTVLHIQHSTWPDHGVPNDSSTVRKILKRLY 547 L +++V R K+ E+ + V+ ++TWPD G+P+ + K L+++ Sbjct: 162 LTVELVRLETYQNFVRRWFKLTDLETQQSREVMQFHYTTWPDFGIPSSPNAFLKFLQQVR 221 Query: 546 YVG---KD-HPIVAHCSAGIGRTGAYITIHNTVERILRGDQAATNLVETVGKFRSQRPGI 379 G +D P V HCSAGIGR+G + + + +L N+ + + + RS R G+ Sbjct: 222 DSGCLSRDVGPAVVHCSAGIGRSGTFCLVDCCL--VLIDKYGECNVSKVLCELRSYRMGL 279 Query: 378 VQTEEQYKFCYHAIVDELKDL 316 +QT +Q F Y AI++ +K L Sbjct: 280 IQTADQLDFSYQAIIEGIKKL 300
>PTPRV_MOUSE (P70289) Receptor-type tyrosine-protein phosphatase V precursor (EC| 3.1.3.48) (Embryonic stem cell protein-tyrosine phosphatase) (ES cell phosphatase) Length = 1705 Score = 72.0 bits (175), Expect = 2e-12 Identities = 38/134 (28%), Positives = 69/134 (51%), Gaps = 4/134 (2%) Frame = -1 Query: 714 IVETRQDGELTLRSVKVQHKESDRVHTVLHIQHSTWPDHGVPNDSST----VRKILKRLY 547 ++ + E T R ++QH + V +Q +TWPDH VP S+ V + + + Sbjct: 1279 LLAEESEDEWTRREFQLQHGAEQKQRRVKQLQFTTWPDHSVPEAPSSLLAFVELVQEEVK 1338 Query: 546 YVGKDHPIVAHCSAGIGRTGAYITIHNTVERILRGDQAATNLVETVGKFRSQRPGIVQTE 367 PI+ HCSAG+GRTG ++ + V ++ ++ ++ TV R RP ++QT Sbjct: 1339 ATQGKGPILVHCSAGVGRTGTFVALLPAVRQL--EEEQVVDVFNTVYILRLHRPLMIQTL 1396 Query: 366 EQYKFCYHAIVDEL 325 QY F + +++++ Sbjct: 1397 SQYIFLHSCLLNKI 1410
>PTPRA_RAT (Q03348) Receptor-type tyrosine-protein phosphatase alpha precursor| (EC 3.1.3.48) (Protein-tyrosine phosphatase alpha) (R-PTP-alpha) Length = 796 Score = 72.0 bits (175), Expect = 2e-12 Identities = 36/133 (27%), Positives = 67/133 (50%), Gaps = 3/133 (2%) Frame = -1 Query: 726 LNIKIVETRQDGELTLRSVKVQHKESDRVHTVLHIQHSTWPDHGVPNDSSTVRKIL---K 556 + +++ + + T+R + V + ++ + WP+ G+P+D + I+ + Sbjct: 652 ITVELKKEEECESYTVRDLLVTNTRENKSRQIRQFHFHGWPEVGIPSDGKGMINIIAAVQ 711 Query: 555 RLYYVGKDHPIVAHCSAGIGRTGAYITIHNTVERILRGDQAATNLVETVGKFRSQRPGIV 376 + +HPI HCSAG GRTG + + +E + + ++ +TV R QRP +V Sbjct: 712 KQQQQSGNHPITVHCSAGAGRTGTFCALSTVLECVKA--EGILDVFQTVKTLRLQRPHMV 769 Query: 375 QTEEQYKFCYHAI 337 Q EQY+FCY + Sbjct: 770 QILEQYEFCYKVV 782 Score = 65.1 bits (157), Expect = 2e-10 Identities = 37/114 (32%), Positives = 63/114 (55%), Gaps = 2/114 (1%) Frame = -1 Query: 666 VQHKESDRVHTVLHIQHSTWPDHGVPNDSSTVRKILKRLYYVGKDHP--IVAHCSAGIGR 493 V +++ R+ T H ++WPD GVP + K LK++ + IV HCSAG+GR Sbjct: 385 VTNRKPQRLITQFHF--TSWPDFGVPFTPIGMLKFLKKVKACNPQYAGAIVVHCSAGVGR 442 Query: 492 TGAYITIHNTVERILRGDQAATNLVETVGKFRSQRPGIVQTEEQYKFCYHAIVD 331 TG ++ I ++ + + ++ V + R+QR +VQT+ QY F Y A+++ Sbjct: 443 TGTFVVIDAMLD--MMHSERKVDVYGFVSRIRAQRCQMVQTDMQYVFIYQALLE 494
>PTN14_HUMAN (Q15678) Tyrosine-protein phosphatase non-receptor type 14 (EC| 3.1.3.48) (Protein-tyrosine phosphatase pez) Length = 1187 Score = 71.6 bits (174), Expect = 2e-12 Identities = 41/130 (31%), Positives = 64/130 (49%), Gaps = 12/130 (9%) Frame = -1 Query: 672 VKVQHKESDRVHTVLHIQHSTWPDHGVPNDSSTVRKILKRLYYV------------GKDH 529 +KV+H S + TV H+Q++ WPDHG P D L+ + V + Sbjct: 1056 LKVKHLLSGQERTVWHLQYTDWPDHGCPEDVQGFLSYLEEIQSVRRHTNSMLEGTKNRHP 1115 Query: 528 PIVAHCSAGIGRTGAYITIHNTVERILRGDQAATNLVETVGKFRSQRPGIVQTEEQYKFC 349 PIV HCSAG+GRTG I + + ++ ++ + R QR ++QT QYKF Sbjct: 1116 PIVVHCSAGVGRTGVLILSELMIYCLEHNEKVEVPMM--LRLLREQRMFMIQTIAQYKFV 1173 Query: 348 YHAIVDELKD 319 Y ++ L++ Sbjct: 1174 YQVLIQFLQN 1183
>PTN23_RAT (O88902) Tyrosine-protein phosphatase non-receptor type 23 (EC| 3.1.3.48) (His-domain-containing protein tyrosine phosphatase) (HD-PTP) (Protein tyrosine phosphatase TD14) (PTP-TD14) (Fragment) Length = 1499 Score = 71.2 bits (173), Expect = 3e-12 Identities = 36/144 (25%), Positives = 78/144 (54%), Gaps = 5/144 (3%) Frame = -1 Query: 726 LNIKIVETRQDGELTLRSVKVQHKESDRVHTVLHIQHSTWPDHGVPNDSSTVRKILKRLY 547 L++ + R R + +Q ++ +++H+ TWP+ G+P+ + + ++ ++ Sbjct: 1179 LSVALSSVRTTDTHVERVLSLQFRDQSLKRSLVHLHFPTWPELGLPDSPGNLLRFIQEVH 1238 Query: 546 --YVGK---DHPIVAHCSAGIGRTGAYITIHNTVERILRGDQAATNLVETVGKFRSQRPG 382 Y+ + PIV HCS+G+GRTGA+ ++ V+ + G + L + V + R QR Sbjct: 1239 AHYLHQRPLHTPIVVHCSSGVGRTGAFALLYAAVQEVEAGSR-IPELPQLVRRMRQQRKH 1297 Query: 381 IVQTEEQYKFCYHAIVDELKDLIR 310 ++Q + KFC+ A+V ++ +++ Sbjct: 1298 MLQEKLHLKFCHEALVRHVEQVLQ 1321
>PTPRR_RAT (O08617) Receptor-type tyrosine-protein phosphatase R precursor (EC| 3.1.3.48) (Protein-tyrosine phosphatase PCPTP1) (Tyrosine phosphatase CBPTP) (PC12-PTP1) Length = 656 Score = 70.9 bits (172), Expect = 4e-12 Identities = 39/135 (28%), Positives = 72/135 (53%), Gaps = 5/135 (3%) Frame = -1 Query: 726 LNIKIVETRQDGELTLRSVKVQHKESDRVHTVLHIQHSTWPDHGVPNDSSTVRKIL---- 559 + + ++ + T+R++ + K V H +++WPDH P+ + + +++ Sbjct: 514 VEVLVIGVNECDNYTIRNLVL--KRGSHTQHVKHYWYTSWPDHKTPDSAQPLLQLMLDVE 571 Query: 558 -KRLYYVGKDHPIVAHCSAGIGRTGAYITIHNTVERILRGDQAATNLVETVGKFRSQRPG 382 RL G+ P+V HCSAGIGRTG +I +++ ++ + + V + R R G Sbjct: 572 EDRLASEGRG-PVVVHCSAGIGRTGCFIATSIGCQQL--KEEGVVDALSIVCQLRVDRGG 628 Query: 381 IVQTEEQYKFCYHAI 337 +VQT EQY+F +HA+ Sbjct: 629 MVQTSEQYEFVHHAL 643
>PTP1_CAEEL (P28191) Tyrosine-protein phosphatase 1 (EC 3.1.3.48)| (Protein-tyrosine phosphatase 1) Length = 1026 Score = 70.9 bits (172), Expect = 4e-12 Identities = 45/138 (32%), Positives = 66/138 (47%), Gaps = 2/138 (1%) Frame = -1 Query: 726 LNIKIVETRQDGELTLRSVKVQHKESDRVHTVLHIQHSTWPDHGVPNDSSTVRKILK--R 553 L IK ++ +Q R ++ + S V +Q+ WPDHGVP+D + + R Sbjct: 879 LMIKCIKDKQTTNCCYREFSIRDRNSSEERRVTQMQYIAWPDHGVPDDPKHFIQFVDEVR 938 Query: 552 LYYVGKDHPIVAHCSAGIGRTGAYITIHNTVERILRGDQAATNLVETVGKFRSQRPGIVQ 373 G PIV HCSAGIGRTG I + T ++ ++ L + V R QR ++Q Sbjct: 939 KARQGSVDPIVVHCSAGIGRTGVLI-LMETAACLVESNEPVYPL-DIVRTMRDQRAMLIQ 996 Query: 372 TEEQYKFCYHAIVDELKD 319 T QY F +I+ D Sbjct: 997 TPGQYTFVCESILRAYHD 1014
>PTPRR_MOUSE (Q62132) Receptor-type tyrosine-protein phosphatase R precursor (EC| 3.1.3.48) (Protein-tyrosine-phosphatase SL) (Phosphotyrosine phosphatase 13) Length = 656 Score = 70.5 bits (171), Expect = 5e-12 Identities = 37/112 (33%), Positives = 62/112 (55%), Gaps = 5/112 (4%) Frame = -1 Query: 657 KESDRVHTVLHIQHSTWPDHGVPNDSSTVRKIL-----KRLYYVGKDHPIVAHCSAGIGR 493 K+ V H +++WPDH P+ + + +++ RL G+ P+V HCSAGIGR Sbjct: 535 KQGSHTQHVKHYWYTSWPDHKTPDSAQPLLQLMLDVEEDRLASEGRG-PVVVHCSAGIGR 593 Query: 492 TGAYITIHNTVERILRGDQAATNLVETVGKFRSQRPGIVQTEEQYKFCYHAI 337 TG +I +++ ++ + + V + R R G+VQT EQY+F +HA+ Sbjct: 594 TGCFIATSIGCQQL--KEEGVVDALSIVCQLRVDRGGMVQTSEQYEFVHHAL 643
>PTN23_MOUSE (Q6PB44) Tyrosine-protein phosphatase non-receptor type 23 (EC| 3.1.3.48) Length = 1692 Score = 70.5 bits (171), Expect = 5e-12 Identities = 34/128 (26%), Positives = 73/128 (57%), Gaps = 5/128 (3%) Frame = -1 Query: 678 RSVKVQHKESDRVHTVLHIQHSTWPDHGVPNDSSTVRKILKRLY--YVGK---DHPIVAH 514 R + +Q ++ +++H+ TWP+ G+P+ + + ++ ++ Y+ + PIV H Sbjct: 1388 RVLSLQFRDQSLKRSLVHLHFPTWPELGLPDSPGNLLRFIQEVHAHYLHQRPLHTPIVVH 1447 Query: 513 CSAGIGRTGAYITIHNTVERILRGDQAATNLVETVGKFRSQRPGIVQTEEQYKFCYHAIV 334 CS+G+GRTGA+ ++ V+ + G+ L + V + R QR ++Q + KFC+ A+V Sbjct: 1448 CSSGVGRTGAFALLYAAVQEVEAGN-GIPELPQLVRRMRQQRKHMLQEKLHLKFCHEALV 1506 Query: 333 DELKDLIR 310 ++ +++ Sbjct: 1507 RHVEQVLQ 1514
>PTPRB_HUMAN (P23467) Receptor-type tyrosine-protein phosphatase beta precursor| (EC 3.1.3.48) (Protein-tyrosine phosphatase beta) (R-PTP-beta) Length = 1997 Score = 70.5 bits (171), Expect = 5e-12 Identities = 39/128 (30%), Positives = 70/128 (54%), Gaps = 5/128 (3%) Frame = -1 Query: 690 ELTLRSVKVQHKESDRVHTVL-HIQHSTWPDHGVPNDSSTVRKILKRLY-YVGKDH---P 526 E T+R K+ +E H ++ H ++ WPDHGVP + ++ + ++ + Y+ + P Sbjct: 1840 EWTIREFKICGEEQLDAHRLIRHFHYTVWPDHGVPETTQSLIQFVRTVRDYINRSPGAGP 1899 Query: 525 IVAHCSAGIGRTGAYITIHNTVERILRGDQAATNLVETVGKFRSQRPGIVQTEEQYKFCY 346 V HCSAG+GRTG +I + ++++ D + ++ V R R +VQTE QY + + Sbjct: 1900 TVVHCSAGVGRTGTFIALDRILQQLDSKD--SVDIYGAVHDLRLHRVHMVQTECQYVYLH 1957 Query: 345 HAIVDELK 322 + D L+ Sbjct: 1958 QCVRDVLR 1965
>PTPRU_HUMAN (Q92729) Receptor-type tyrosine-protein phosphatase U precursor (EC| 3.1.3.48) (R-PTP-U) (Protein-tyrosine phosphatase J) (PTP-J) (Pancreatic carcinoma phosphatase 2) (PCP-2) Length = 1430 Score = 70.1 bits (170), Expect = 7e-12 Identities = 40/134 (29%), Positives = 69/134 (51%), Gaps = 2/134 (1%) Frame = -1 Query: 726 LNIKIVETRQDGELTLRSVKVQHKESDRVHTVLHIQHSTWPDHGVPNDSSTVRKILKRLY 547 + I +V+T E +R+ ++ + H V + WP+HGVP ++ + ++R+ Sbjct: 996 IKIMLVKTETLAEYVVRTFALERRGYSARHEVRQSHFTAWPEHGVPYHATGLLAFIRRVK 1055 Query: 546 YVGKDH--PIVAHCSAGIGRTGAYITIHNTVERILRGDQAATNLVETVGKFRSQRPGIVQ 373 PIV HCSAG GRTG YI + ++ + + ++ V S+R ++Q Sbjct: 1056 ASTPPDAGPIVIHCSAGTGRTGCYIVLDVMLD--MAECEGVVDIYNCVKTLCSRRVNMIQ 1113 Query: 372 TEEQYKFCYHAIVD 331 TEEQY F + AI++ Sbjct: 1114 TEEQYIFIHDAILE 1127 Score = 44.3 bits (103), Expect = 4e-04 Identities = 40/150 (26%), Positives = 64/150 (42%), Gaps = 13/150 (8%) Frame = -1 Query: 726 LNIKIVETRQDGELTLRSVKVQH----KESDRVHTVLHIQHSTWPDHGVPNDSSTVRKIL 559 + ++ + D +L R +VQ+ +E D + V H Q W + DS + L Sbjct: 1287 MEVEFMSGTADEDLVARVFRVQNISRLQEGDLL--VRHFQFLRWSAYRDTPDSK--KAFL 1342 Query: 558 KRLYYVGK------DHPIVAHCSAGIGRTGAYITIHNTVERILRGDQAATNLVET---VG 406 L V K D + HC G GR+G + +E I NLV+ Sbjct: 1343 HLLAEVDKWQAESGDGRTIVHCLNGGGRSGTFCACATVLEMI-----RCHNLVDVFFAAQ 1397 Query: 405 KFRSQRPGIVQTEEQYKFCYHAIVDELKDL 316 R+ +P +V+T +QY FCY ++ L+ L Sbjct: 1398 TLRNYKPNMVETMDQYHFCYDVALEYLEGL 1427
>PTN22_MOUSE (P29352) Tyrosine-protein phosphatase non-receptor type 22 (EC| 3.1.3.48) (Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP) Length = 802 Score = 70.1 bits (170), Expect = 7e-12 Identities = 39/133 (29%), Positives = 69/133 (51%), Gaps = 6/133 (4%) Frame = -1 Query: 702 RQDGELTLRSVKVQHKESDRVHTVLHIQHSTWPDHGVPNDSSTVRKIL--KRLYYVGKDH 529 ++ + +R++K + R+ + + WPDH VP+ + +++ R Y Sbjct: 164 KKKSDYKIRTLKAKFNNETRI--IYQFHYKNWPDHDVPSSIDPILQLIWDMRCYQEDDCV 221 Query: 528 PIVAHCSAGIGRTGAYITIHNT----VERILRGDQAATNLVETVGKFRSQRPGIVQTEEQ 361 PI HCSAG GRTG + T + I+ + + NL++ + R+QRP +VQT+EQ Sbjct: 222 PICIHCSAGCGRTGVICAVDYTWMLLKDGIIPKNFSVFNLIQ---EMRTQRPSLVQTQEQ 278 Query: 360 YKFCYHAIVDELK 322 Y+ Y A+++ K Sbjct: 279 YELVYSAVLELFK 291
>PTP2_CAEEL (P28192) Tyrosine-protein phosphatase 2 (EC 3.1.3.48)| (Protein-tyrosine phosphatase 2) Length = 1156 Score = 69.3 bits (168), Expect = 1e-11 Identities = 48/130 (36%), Positives = 68/130 (52%), Gaps = 3/130 (2%) Frame = -1 Query: 687 LTLRSVKVQHKESDRVHTVLHIQHSTWPDHGVPNDSSTVRKILKRLYYVGKDH---PIVA 517 L L+ K +VH LH WPDHGVP S+V +L ++Y H P+V Sbjct: 804 LDLKIAKAVPAVERKVHQ-LHFMG--WPDHGVP---SSVFPLLSFVHYTSDIHSTGPVVV 857 Query: 516 HCSAGIGRTGAYITIHNTVERILRGDQAATNLVETVGKFRSQRPGIVQTEEQYKFCYHAI 337 HCSAG+GR+G+YI + + ++ N+ + R QR +VQT EQY FC+ AI Sbjct: 858 HCSAGVGRSGSYILVDSMRRHLI--SFRRLNVQGHLTHMRRQRAKLVQTLEQYIFCHEAI 915 Query: 336 VDELKDLIRN 307 + LIR+ Sbjct: 916 ----RQLIRH 921
>PTN14_MOUSE (Q62130) Tyrosine-protein phosphatase non-receptor type 14 (EC| 3.1.3.48) (Protein-tyrosine phosphatase PTP36) Length = 1189 Score = 69.3 bits (168), Expect = 1e-11 Identities = 44/131 (33%), Positives = 65/131 (49%), Gaps = 13/131 (9%) Frame = -1 Query: 672 VKVQHKESDRVHTVLHIQHSTWPDHGVPNDSSTVRKILKRLYYV------------GKDH 529 +KV+H S + TV H+Q++ WP HG P D L+ + V + Sbjct: 1058 LKVKHLLSGQERTVWHLQYTDWPHHGCPEDVQGFLSYLEEIQSVRRHTNSVLEGIRTRHP 1117 Query: 528 PIVAHCSAGIGRTGAYITIHNTVERILRGDQAATNLVETVGKF-RSQRPGIVQTEEQYKF 352 PIV HCSAG+GRTG I + + ++ V T+ +F R QR ++QT QYKF Sbjct: 1118 PIVVHCSAGVGRTGVVILSELMIYCLEHNEKVE---VPTMLRFLREQRMFMIQTIAQYKF 1174 Query: 351 CYHAIVDELKD 319 Y +V L++ Sbjct: 1175 VYQVLVQFLQN 1185
>PTP10_DROME (P35992) Tyrosine-protein phosphatase 10D precursor (EC 3.1.3.48)| (Receptor-linked protein-tyrosine phosphatase 10D) (DPTP10D) Length = 1631 Score = 69.3 bits (168), Expect = 1e-11 Identities = 37/97 (38%), Positives = 55/97 (56%), Gaps = 2/97 (2%) Frame = -1 Query: 627 HIQHSTWPDHGVPNDSSTVRKILK--RLYYVGKDHPIVAHCSAGIGRTGAYITIHNTVER 454 H +TWPD GVPN T+ + ++ R + PIV HCSAG+GR+G +IT+ +++ Sbjct: 1428 HFHFTTWPDFGVPNPPQTLVRFVRAFRDRIGAEQRPIVVHCSAGVGRSGTFITLDRILQQ 1487 Query: 453 ILRGDQAATNLVETVGKFRSQRPGIVQTEEQYKFCYH 343 I D ++ V R +R +VQTE+QY C H Sbjct: 1488 INTSDY--VDIFGIVYAMRKERVWMVQTEQQY-ICIH 1521
>PTP3_DICDI (P54637) Tyrosine-protein phosphatase 3 (EC 3.1.3.48)| (Protein-tyrosine-phosphate phosphohydrolase 3) Length = 989 Score = 68.6 bits (166), Expect = 2e-11 Identities = 42/136 (30%), Positives = 72/136 (52%), Gaps = 11/136 (8%) Frame = -1 Query: 690 ELTLRSVKVQHKESDRVHTVLHIQHSTWPDHGVPNDSSTVRKIL-------KRLYYVGKD 532 ++ + S+ + K + V+ + ++ WPD G P SS +R + R + Sbjct: 583 DIGVSSLHLYKKGEEFPREVVLLHYTQWPDCGAPPSSSHIRTLSVMVNTFKARGSAKNTN 642 Query: 531 HPIVAHCSAGIGRTGAYITIHNTVERILR----GDQAATNLVETVGKFRSQRPGIVQTEE 364 P++ HCSAGIGR+G +I+I+ + +I R Q ++ ++V + R QR G+VQT + Sbjct: 643 GPVIVHCSAGIGRSGTFISININMAKIERFGNDPSQMNISIKDSVLELRRQRRGMVQTLD 702 Query: 363 QYKFCYHAIVDELKDL 316 QY F + I D L D+ Sbjct: 703 QYIFIFKVINDVLTDM 718
>PTN5_MOUSE (P54830) Tyrosine-protein phosphatase non-receptor type 5 (EC| 3.1.3.48) (Protein-tyrosine phosphatase striatum-enriched) (STEP) (Neural-specific protein-tyrosine phosphatase) Length = 541 Score = 68.2 bits (165), Expect = 3e-11 Identities = 37/132 (28%), Positives = 71/132 (53%), Gaps = 5/132 (3%) Frame = -1 Query: 717 KIVETRQDGELTLRSVKVQHKESDRVHTVLHIQHSTWPDHGVPNDSSTVRKILKRLYYVG 538 K++ T + LR + ++ +R T+ H ++WPD P+ + + +++ + Sbjct: 404 KVIHTE---DYRLRLISLRRGTEER--TLKHYWFTSWPDQKTPDRAPPLLHLVREVEEAA 458 Query: 537 KDH-----PIVAHCSAGIGRTGAYITIHNTVERILRGDQAATNLVETVGKFRSQRPGIVQ 373 + PI+ HCSAGIGRTG +I +++ R + ++++T + R R G++Q Sbjct: 459 QQEGPHCSPIIVHCSAGIGRTGCFIATSICCQQLRR--EGVVDILKTTCQLRQDRGGMIQ 516 Query: 372 TEEQYKFCYHAI 337 T EQY+F +HA+ Sbjct: 517 TCEQYQFVHHAM 528
>PTN21_MOUSE (Q62136) Tyrosine-protein phosphatase non-receptor type 21 (EC| 3.1.3.48) (Protein-tyrosine phosphatase PTP-RL10) Length = 1176 Score = 67.0 bits (162), Expect = 6e-11 Identities = 40/128 (31%), Positives = 62/128 (48%), Gaps = 11/128 (8%) Frame = -1 Query: 672 VKVQHKESDRVHTVLHIQHSTWPDHGVPNDSSTVRKILKRLYYV---------GKDH--P 526 +K++H + + TV H+Q++ WP+HG P D L+ + V K H P Sbjct: 1046 LKMKHLLTGQERTVWHLQYTDWPEHGCPEDLKGFLSYLEEIQSVRRHTNSTSEPKSHNPP 1105 Query: 525 IVAHCSAGIGRTGAYITIHNTVERILRGDQAATNLVETVGKFRSQRPGIVQTEEQYKFCY 346 ++ HCSAG+GRTG I V + + ++ + R QR +VQT QY F Y Sbjct: 1106 LLVHCSAGVGRTGVVILSEIMVACLEHNE--VLDIPRVLDMLRQQRMMLVQTLGQYTFVY 1163 Query: 345 HAIVDELK 322 ++ LK Sbjct: 1164 RVLIQFLK 1171
>PTN21_RAT (Q62728) Tyrosine-protein phosphatase non-receptor type 21 (EC| 3.1.3.48) (Protein-tyrosine phosphatase 2E) Length = 1175 Score = 66.6 bits (161), Expect = 7e-11 Identities = 38/128 (29%), Positives = 62/128 (48%), Gaps = 11/128 (8%) Frame = -1 Query: 672 VKVQHKESDRVHTVLHIQHSTWPDHGVPNDSSTVRKILKRLYYVGK-----------DHP 526 +K++H + + TV H+Q++ WP+HG P D L+ + V + + P Sbjct: 1045 LKMKHLLTGQERTVWHLQYTDWPEHGCPEDLKGFLSYLEEIQSVRRHTNSTSEPRSPNPP 1104 Query: 525 IVAHCSAGIGRTGAYITIHNTVERILRGDQAATNLVETVGKFRSQRPGIVQTEEQYKFCY 346 ++ HCSAG+GRTG I V + + ++ + R QR +VQT QY F Y Sbjct: 1105 LLVHCSAGVGRTGVVILSEIMVACLEHNE--VLDIPRVLELLRQQRMMLVQTLSQYTFVY 1162 Query: 345 HAIVDELK 322 ++ LK Sbjct: 1163 RVLIQFLK 1170
>PTN5_RAT (P35234) Tyrosine-protein phosphatase non-receptor type 5 (EC| 3.1.3.48) (Protein-tyrosine phosphatase striatum-enriched) (STEP) (Neural-specific protein-tyrosine phosphatase) Length = 369 Score = 65.5 bits (158), Expect = 2e-10 Identities = 36/132 (27%), Positives = 70/132 (53%), Gaps = 5/132 (3%) Frame = -1 Query: 717 KIVETRQDGELTLRSVKVQHKESDRVHTVLHIQHSTWPDHGVPNDSSTVRKILKRLYYVG 538 K++ T + LR + ++ +R + H ++WPD P+ + + +++ + Sbjct: 232 KVIHTE---DYRLRLISLRRGTEER--GLKHYWFTSWPDQKTPDRAPPLLHLVREVEEAA 286 Query: 537 KDH-----PIVAHCSAGIGRTGAYITIHNTVERILRGDQAATNLVETVGKFRSQRPGIVQ 373 + PI+ HCSAGIGRTG +I +++ R + ++++T + R R G++Q Sbjct: 287 QQEGPHCSPIIVHCSAGIGRTGCFIATSICCQQLRR--EGVVDILKTTCQLRQDRGGMIQ 344 Query: 372 TEEQYKFCYHAI 337 T EQY+F +HA+ Sbjct: 345 TCEQYQFVHHAM 356
>PTN21_HUMAN (Q16825) Tyrosine-protein phosphatase non-receptor type 21 (EC| 3.1.3.48) (Protein-tyrosine phosphatase D1) Length = 1174 Score = 65.5 bits (158), Expect = 2e-10 Identities = 37/128 (28%), Positives = 62/128 (48%), Gaps = 11/128 (8%) Frame = -1 Query: 672 VKVQHKESDRVHTVLHIQHSTWPDHGVPNDSSTVRKILKRLYYVGK-----------DHP 526 +K++H + + TV H+Q++ WP+HG P D L+ + V + + P Sbjct: 1044 LKMKHLLTGQERTVWHLQYTDWPEHGCPEDLKGFLSYLEEIQSVRRHTNSTSDPQSPNPP 1103 Query: 525 IVAHCSAGIGRTGAYITIHNTVERILRGDQAATNLVETVGKFRSQRPGIVQTEEQYKFCY 346 ++ HCSAG+GRTG I + + + ++ + R QR +VQT QY F Y Sbjct: 1104 LLVHCSAGVGRTGVVILSEIMIACLEHNE--VLDIPRVLDMLRQQRMMLVQTLCQYTFVY 1161 Query: 345 HAIVDELK 322 ++ LK Sbjct: 1162 RVLIQFLK 1169
>PTP69_DROME (P16620) Tyrosine-protein phosphatase 69D precursor (EC 3.1.3.48)| (Protein-tyrosine-phosphate phosphohydrolase) (DPTP) Length = 1462 Score = 65.5 bits (158), Expect = 2e-10 Identities = 39/138 (28%), Positives = 71/138 (51%), Gaps = 8/138 (5%) Frame = -1 Query: 720 IKIVETRQDGELTLRSVKVQH------KESDRVHTVLHIQHSTWPDHGVPNDSSTVRKIL 559 +K + R+ G+ R++ V +E DR + + TW D P + K + Sbjct: 1021 VKFAQERKTGDYIERTLNVSKNKANVGEEEDR-RQITQYHYLTWKDFMAPEHPHGIIKFI 1079 Query: 558 KRL--YYVGKDHPIVAHCSAGIGRTGAYITIHNTVERILRGDQAATNLVETVGKFRSQRP 385 +++ Y + PI+ HCSAG+GRTG + + + ++++ D + ++ TV R QR Sbjct: 1080 RQINSVYSLQRGPILVHCSAGVGRTGTLVALDSLIQQLEEED--SVSIYNTVCDLRHQRN 1137 Query: 384 GIVQTEEQYKFCYHAIVD 331 +VQ+ +QY F Y A++D Sbjct: 1138 FLVQSLKQYIFLYRALLD 1155 Score = 50.1 bits (118), Expect = 7e-06 Identities = 34/139 (24%), Positives = 64/139 (46%), Gaps = 9/139 (6%) Frame = -1 Query: 720 IKIVETRQDGELTLRSVKVQHKESDRVHTVLHIQHSTWP--DHGVPNDSSTVRKILKRLY 547 +K V + T R V + + D V Q++ WP D VP + +++ + Y Sbjct: 1313 VKYVHSESCPYYTRREFYVTNCKIDDTLKVTQFQYNGWPTVDGEVPEVCRGIIELVDQAY 1372 Query: 546 YVGKDH-------PIVAHCSAGIGRTGAYITIHNTVERILRGDQAATNLVETVGKFRSQR 388 K++ P+ HCS G R+ ++ + V+ + + ++ T K RSQR Sbjct: 1373 NHYKNNKNSGCRSPLTVHCSLGTDRSSIFVAMCILVQHLRL--EKCVDICATTRKLRSQR 1430 Query: 387 PGIVQTEEQYKFCYHAIVD 331 G++ + QY+F + AI++ Sbjct: 1431 TGLINSYAQYEFLHRAIIN 1449
>PTN12_MOUSE (P35831) Tyrosine-protein phosphatase non-receptor type 12 (EC| 3.1.3.48) (Protein-tyrosine phosphatase P19) (P19-PTP) (MPTP-PEST) Length = 775 Score = 64.7 bits (156), Expect = 3e-10 Identities = 40/109 (36%), Positives = 57/109 (52%), Gaps = 3/109 (2%) Frame = -1 Query: 654 ESDRVHTVLHIQHSTWPDHGVPNDSSTVRKI--LKRLYYVGKDHPIVAHCSAGIGRTGAY 481 ES R++ ++ WPDH VP+ ++ + L R Y +D PI HCSAG GRTGA Sbjct: 185 ESRRLYQFHYVN---WPDHDVPSSFDSILDMISLMRKYQEHEDVPICIHCSAGCGRTGAI 241 Query: 480 ITIHNTVERILRGD-QAATNLVETVGKFRSQRPGIVQTEEQYKFCYHAI 337 I T + G N+ + + R+QR VQT+EQY+ + AI Sbjct: 242 CAIDYTWNLLKAGKIPEEFNVFNLIQEMRTQRHSAVQTKEQYELVHRAI 290
>PTN12_HUMAN (Q05209) Tyrosine-protein phosphatase non-receptor type 12 (EC| 3.1.3.48) (Protein-tyrosine phosphatase G1) (PTPG1) Length = 780 Score = 64.7 bits (156), Expect = 3e-10 Identities = 40/109 (36%), Positives = 57/109 (52%), Gaps = 3/109 (2%) Frame = -1 Query: 654 ESDRVHTVLHIQHSTWPDHGVPNDSSTVRKI--LKRLYYVGKDHPIVAHCSAGIGRTGAY 481 ES R++ ++ WPDH VP+ ++ + L R Y +D PI HCSAG GRTGA Sbjct: 185 ESRRLYQFHYVN---WPDHDVPSSFDSILDMISLMRKYQEHEDVPICIHCSAGCGRTGAI 241 Query: 480 ITIHNTVERILRGD-QAATNLVETVGKFRSQRPGIVQTEEQYKFCYHAI 337 I T + G N+ + + R+QR VQT+EQY+ + AI Sbjct: 242 CAIDYTWNLLKAGKIPEEFNVFNLIQEMRTQRHSAVQTKEQYELVHRAI 290
>PTP1_YEAST (P25044) Tyrosine-protein phosphatase 1 (EC 3.1.3.48)| (Protein-tyrosine phosphatase 1) (PTPase 1) Length = 335 Score = 62.0 bits (149), Expect = 2e-09 Identities = 37/117 (31%), Positives = 57/117 (48%), Gaps = 16/117 (13%) Frame = -1 Query: 642 VHTVLHIQHSTWPDHGVPNDSSTVRKILKRLYYVG-KDHPIVAHCSAGIGRTGAYITI-- 472 V TV H W D P + + ++ + + + +PI+ HCSAG+GRTG +I + Sbjct: 208 VKTVHHFYFDLWKDMNKPEEVVPIMELCAHSHSLNSRGNPIIVHCSAGVGRTGTFIALDH 267 Query: 471 --------HNTVERILRGDQAATN-----LVETVGKFRSQRPGIVQTEEQYKFCYHA 340 N ER D+A + + V + RSQR +VQT++Q+ F YHA Sbjct: 268 LMHDTLDFKNITERSRHSDRATEEYTRDLIEQIVLQLRSQRMKMVQTKDQFLFIYHA 324
>PTN5_HUMAN (P54829) Tyrosine-protein phosphatase non-receptor type 5 (EC| 3.1.3.48) (Protein-tyrosine phosphatase striatum-enriched) (STEP) (Neural-specific protein-tyrosine phosphatase) Length = 541 Score = 60.8 bits (146), Expect = 4e-09 Identities = 36/132 (27%), Positives = 69/132 (52%), Gaps = 5/132 (3%) Frame = -1 Query: 717 KIVETRQDGELTLRSVKVQHKESDRVHTVLHIQHSTWPDHGVPNDSSTVRKILKRLYYVG 538 K++ T +D L L S+K +E + H ++WPD P+ + + +++ + Sbjct: 404 KVIHT-EDYRLRLISLKSGTEERG----LKHYWFTSWPDQKTPDRAPPLLHLVREVEEAA 458 Query: 537 KDH-----PIVAHCSAGIGRTGAYITIHNTVERILRGDQAATNLVETVGKFRSQRPGIVQ 373 + PI+ HCSAGIGRTG +I +++ + + ++++T + R R G++Q Sbjct: 459 QQEGPHCAPIIVHCSAGIGRTGCFIATSICCQQLRQ--EGVVDILKTTCQLRQDRGGMIQ 516 Query: 372 TEEQYKFCYHAI 337 EQY+F +H + Sbjct: 517 HCEQYQFVHHVM 528
>PYP1_SCHPO (P27574) Tyrosine-protein phosphatase 1 (EC 3.1.3.48)| (Protein-tyrosine phosphatase 1) (PTPase 1) Length = 550 Score = 59.3 bits (142), Expect = 1e-08 Identities = 41/141 (29%), Positives = 66/141 (46%), Gaps = 12/141 (8%) Frame = -1 Query: 708 ETRQDGELTLRSVKVQHKESDRVHTVLHIQHSTWPDHGVPNDSSTVRKILKRLYYVGKDH 529 E + LR ++Q+ V V H Q+ W D P + V+ +++ L YV H Sbjct: 405 ENVDNSRFILRKFEIQNANFPSVKKVHHYQYPNWSDCNSPEN---VKSMVEFLKYVNNSH 461 Query: 528 P---IVAHCSAGIGRTGAYITIHNTVERILRGDQAATN---------LVETVGKFRSQRP 385 + HCSAG+GRTG +I + +T+ R + N + + V R QR Sbjct: 462 GSGNTIVHCSAGVGRTGTFIVL-DTILRFPESKLSGFNPSVADSSDVVFQLVDHIRKQRM 520 Query: 384 GIVQTEEQYKFCYHAIVDELK 322 +VQT Q+K+ Y ++D L+ Sbjct: 521 KMVQTFTQFKYVYD-LIDSLQ 540
>PYP3_SCHPO (P32587) Tyrosine-protein phosphatase 3 (EC 3.1.3.48)| (Protein-tyrosine phosphatase 3) (PTPase 3) Length = 303 Score = 57.8 bits (138), Expect = 3e-08 Identities = 35/106 (33%), Positives = 54/106 (50%), Gaps = 10/106 (9%) Frame = -1 Query: 633 VLHIQHSTWPDHGVPNDSS--TVRKILKRLYYVG--KDHPIVAHCSAGIGRTGAYITIHN 466 +LH ++ WPD G P+ S ++ + +K L Y + PI+ HCSAG GRTG ++ + Sbjct: 183 ILHFYYNGWPDFGAPHTFSLLSLTRYIKSLSYSPDFETAPIIVHCSAGCGRTGTFMALFE 242 Query: 465 TVERILRGDQAAT------NLVETVGKFRSQRPGIVQTEEQYKFCY 346 + + D +T N+ V RSQR VQ+ +Q F Y Sbjct: 243 ILSQ--TDDSTSTSKFEVDNIANIVSSLRSQRMQSVQSVDQLVFLY 286
>PYP2_SCHPO (P32586) Tyrosine-protein phosphatase 2 (EC 3.1.3.48)| (Protein-tyrosine phosphatase 2) (PTPase 2) Length = 711 Score = 56.2 bits (134), Expect = 1e-07 Identities = 35/104 (33%), Positives = 51/104 (49%), Gaps = 7/104 (6%) Frame = -1 Query: 627 HIQHSTWPDHGVPNDSSTVRKILKRLYYVGKDHPIVAHCSAGIGRTGAYITIHNTVERIL 448 H TW D P D ++ I++ + V D P+ HCSAG+GRTG +I + ++ Sbjct: 593 HFWVHTWFDKTHP-DIESITGIIRCIDKVPNDGPMFVHCSAGVGRTGTFIAVDQILQVPK 651 Query: 447 RGDQAATNLVET-------VGKFRSQRPGIVQTEEQYKFCYHAI 337 TNL ++ V RSQR +VQ EQ+KF Y + Sbjct: 652 NILPKTTNLEDSKDFIFNCVNSLRSQRMKMVQNFEQFKFLYDVV 695
>PTP1_DICDI (P34137) Tyrosine-protein phosphatase 1 (EC 3.1.3.48)| (Protein-tyrosine-phosphate phosphohydrolase 1) Length = 521 Score = 53.1 bits (126), Expect = 8e-07 Identities = 25/91 (27%), Positives = 46/91 (50%), Gaps = 8/91 (8%) Frame = -1 Query: 723 NIKIVETRQDGELTLRSVKVQHKESDRVHTVLHIQHSTWPDHGVPNDSSTVRKILKRLYY 544 ++++VE QD E + + ++ + Q+ WPDH +P+ + R++L + Sbjct: 232 SVELVEVIQDPEREIITRNIRLTFEGETRDITQYQYEGWPDHNIPDHTQPFRQLLHSITN 291 Query: 543 --------VGKDHPIVAHCSAGIGRTGAYIT 475 ++ PI+ HCSAG+GRTG + T Sbjct: 292 RQNQIIPSSDRNVPIIVHCSAGVGRTGTFCT 322 Score = 43.5 bits (101), Expect = 7e-04 Identities = 20/34 (58%), Positives = 23/34 (67%) Frame = -1 Query: 426 NLVETVGKFRSQRPGIVQTEEQYKFCYHAIVDEL 325 NL V K R QRPG+VQ EQY FCY I+DE+ Sbjct: 438 NLFSIVLKLREQRPGMVQQLEQYLFCYKTILDEI 471
>PTP3_YEAST (P40048) Tyrosine-protein phosphatase 3 (EC 3.1.3.48)| (Protein-tyrosine phosphatase 3) (PTPase 3) Length = 928 Score = 50.8 bits (120), Expect = 4e-06 Identities = 35/146 (23%), Positives = 60/146 (41%), Gaps = 25/146 (17%) Frame = -1 Query: 696 DGELTLRSVKVQHKESDRVHTVLHIQHSTWPDHG-----------VPNDSSTVRKILKRL 550 D + +R + + + + ++ + +L IQ WPD G + + + + R Sbjct: 731 DDAILIRQILLTYHDQEKPYELLQIQVKNWPDLGTLLNPISILQAINVKNHIIDTLFARN 790 Query: 549 YYVGKDHP-IVAHCSAGIGRTGAYITIHNTVERILRGDQAATNLVE-------------T 412 YY P I+ HCSAG GRTG TI + + + V+ T Sbjct: 791 YYQNDQLPTILVHCSAGCGRTGTLCTIDSILSNFEMFEMLQKEFVKLKYPAKLFDPISWT 850 Query: 411 VGKFRSQRPGIVQTEEQYKFCYHAIV 334 + FR +R +VQ Q+ F Y ++ Sbjct: 851 INIFRKERISMVQNINQFIFIYDCLL 876
>PTP2_YEAST (P29461) Tyrosine-protein phosphatase 2 (EC 3.1.3.48)| (Protein-tyrosine phosphatase 2) (PTPase 2) Length = 750 Score = 43.5 bits (101), Expect = 7e-04 Identities = 28/88 (31%), Positives = 46/88 (52%), Gaps = 13/88 (14%) Frame = -1 Query: 528 PIVAHCSAGIGRTGAYITIHNTVERILRGDQAATNLVET-----------VGKFRSQRPG 382 P++ HCSAG GRTG ++T+ + + IL +N ++ V + R QR Sbjct: 661 PLLVHCSAGCGRTGVFVTL-DFLLSILSPTTNHSNKIDVWNMTQDLIFIIVNELRKQRIS 719 Query: 381 IVQTEEQYKFCYHAIVD--ELKDLIRNS 304 +VQ QY CY A+++ L+ I+N+ Sbjct: 720 MVQNLTQYIACYEALLNYFALQKQIKNA 747
>YKCA_CAEEL (P42083) Putative tyrosine-protein phosphatase B0280.11 (EC| 3.1.3.48) Length = 441 Score = 40.0 bits (92), Expect = 0.007 Identities = 27/93 (29%), Positives = 41/93 (44%), Gaps = 5/93 (5%) Frame = -1 Query: 609 WPDHGVPNDS-----STVRKILKRLYYVGKDHPIVAHCSAGIGRTGAYITIHNTVERILR 445 WPD +P S +T + + D + G GR G+++ +E++ Sbjct: 306 WPDGKIPTVSYGRIAATAASVFDS--DIDSDATCAIVSNYGAGRAGSFLVGVQAIEKLQA 363 Query: 444 GDQAATNLVETVGKFRSQRPGIVQTEEQYKFCY 346 GD A N+ E RSQRP ++T QY F Y Sbjct: 364 GD--APNIKEIAMSIRSQRPCAIETLPQYVFTY 394
>PTP27_STYPL (P28219) Tyrosine-protein phosphatase 27 (EC 3.1.3.48) (Fragment)| Length = 114 Score = 38.9 bits (89), Expect = 0.016 Identities = 26/70 (37%), Positives = 33/70 (47%), Gaps = 6/70 (8%) Frame = -1 Query: 711 VETRQDGELTL--RSVKVQHKESDRVHTVLHIQHSTWPDHGVPNDSSTV----RKILKRL 550 VE RQ+ + R V E TV Q WPDHGVP +S + R +LK Sbjct: 44 VENRQEVNYSAFRRRVFSVVSEKQEQLTVYQYQFLKWPDHGVPQTTSNLFRMHRAVLKSC 103 Query: 549 YYVGKDHPIV 520 +G D+PIV Sbjct: 104 QELGNDNPIV 113
>FLP1_SCHPO (Q9P7H1) Tyrosine-protein phosphatase CDC14 homolog (EC 3.1.3.48)| (CDC fourteen-like phosphatase 1) Length = 537 Score = 38.5 bits (88), Expect = 0.021 Identities = 28/109 (25%), Positives = 47/109 (43%) Frame = -1 Query: 684 TLRSVKVQHKESDRVHTVLHIQHSTWPDHGVPNDSSTVRKILKRLYYVGKDHPIVAHCSA 505 T +V ++HKE ++ + T P+ S V++ + V +D I HC A Sbjct: 242 TFENVGIRHKE-------MYFEDGTVPE------LSLVKEFIDLTEEVEEDGVIAVHCKA 288 Query: 504 GIGRTGAYITIHNTVERILRGDQAATNLVETVGKFRSQRPGIVQTEEQY 358 G+GRTG I + + + E + R RPG+V +Q+ Sbjct: 289 GLGRTGCLIGAYLIYKHCFTAN-------EVIAYMRIMRPGMVVGPQQH 330
>PTP8_STYPL (P28200) Tyrosine-protein phosphatase 8 (EC 3.1.3.48) (Fragment)| Length = 112 Score = 38.5 bits (88), Expect = 0.021 Identities = 23/74 (31%), Positives = 37/74 (50%), Gaps = 1/74 (1%) Frame = -1 Query: 720 IKIVETRQDGELTLRSVKVQHKESDRV-HTVLHIQHSTWPDHGVPNDSSTVRKILKRLYY 544 I+I R T+R+++V++ E D HTV H ++ W DH P +R +L + Sbjct: 38 IEIKNVRNADHYTVRTIEVRNTEEDNATHTVYHYWYAEWLDHDTP---EKLRGLLTLIQE 94 Query: 543 VGKDHPIVAHCSAG 502 VG P +A+ G Sbjct: 95 VGLRCPDIANSEYG 108
>PTP2_STYPL (P28194) Tyrosine-protein phosphatase 2 (EC 3.1.3.48) (Fragment)| Length = 127 Score = 37.4 bits (85), Expect = 0.047 Identities = 17/40 (42%), Positives = 22/40 (55%) Frame = -1 Query: 663 QHKESDRVHTVLHIQHSTWPDHGVPNDSSTVRKILKRLYY 544 Q +E V + H+Q WPDHGVP +S + RLYY Sbjct: 76 QTEEEPEVRYITHLQCKRWPDHGVPKSTSAI----FRLYY 111
>PTP11_STYPL (P28203) Tyrosine-protein phosphatase 11 (EC 3.1.3.48) (Fragment)| Length = 114 Score = 36.6 bits (83), Expect = 0.081 Identities = 16/45 (35%), Positives = 25/45 (55%) Frame = -1 Query: 690 ELTLRSVKVQHKESDRVHTVLHIQHSTWPDHGVPNDSSTVRKILK 556 E T+R K+ H + R V ++ WPDHGVP + T+ K ++ Sbjct: 54 EWTIREFKITHGANTR--RVRQFHYTVWPDHGVPETTETLVKFIR 96
>PTP12_STYPL (P28204) Tyrosine-protein phosphatase 12 (EC 3.1.3.48) (Fragment)| Length = 105 Score = 36.6 bits (83), Expect = 0.081 Identities = 16/59 (27%), Positives = 32/59 (54%), Gaps = 4/59 (6%) Frame = -1 Query: 720 IKIVETRQDGELTLRSVKVQHKE-SDRVHTVLHIQHSTWPDHGVPNDSS---TVRKILK 556 + ++ G++ R K+ H+ +R V+ ++ WPDHGVP +S +R+I++ Sbjct: 44 VSCIDNTTLGQIIRRKFKISHQSYPNRTQVVVQYHYTAWPDHGVPQTTSELFNLRRIVR 102
>DUS23_MOUSE (Q6NT99) Dual specificity protein phosphatase 23 (EC 3.1.3.48) (EC| 3.1.3.16) (Low molecular mass dual specificity phosphatase 3) (LDP-3) Length = 150 Score = 36.2 bits (82), Expect = 0.11 Identities = 19/54 (35%), Positives = 26/54 (48%) Frame = -1 Query: 516 HCSAGIGRTGAYITIHNTVERILRGDQAATNLVETVGKFRSQRPGIVQTEEQYK 355 HC+ G GRTG + + ER L A + + R RPG ++T EQ K Sbjct: 94 HCALGFGRTGTMLACYLVKERALAAGDA-------IAEIRRLRPGSIETYEQEK 140
>PTP9_STYPL (P28201) Tyrosine-protein phosphatase 9 (EC 3.1.3.48) (Fragment)| Length = 111 Score = 35.0 bits (79), Expect = 0.24 Identities = 16/60 (26%), Positives = 31/60 (51%), Gaps = 2/60 (3%) Frame = -1 Query: 723 NIKIVETRQDG--ELTLRSVKVQHKESDRVHTVLHIQHSTWPDHGVPNDSSTVRKILKRL 550 +IK+ +T + + T+R+ +Q + V V + WPDHGVP + + ++R+ Sbjct: 39 SIKVSQTHIEDLCDYTIRTFVIQQFDGYDVREVKQFHFTAWPDHGVPTRPTNILSFIRRV 98
>PTP21_STYPL (P28213) Tyrosine-protein phosphatase 21 (EC 3.1.3.48) (Fragment)| Length = 115 Score = 35.0 bits (79), Expect = 0.24 Identities = 20/67 (29%), Positives = 34/67 (50%), Gaps = 4/67 (5%) Frame = -1 Query: 708 ETRQDGELTLRSVKVQHKESDRVHTVLHIQHSTWPDHGVPNDSSTV----RKILKRLYYV 541 E R G L +R +++ E V Q++ WPDH VP +S + + +++ L + Sbjct: 49 EVRYSGFL-VRKFQIESVEKMITMEVFQYQYTNWPDHSVPYTTSNLVRMHKNVIQLLAEI 107 Query: 540 GKDHPIV 520 G D P+V Sbjct: 108 GGDAPMV 114
>DUS23_HUMAN (Q9BVJ7) Dual specificity protein phosphatase 23 (EC 3.1.3.48) (EC| 3.1.3.16) (Low molecular mass dual specificity phosphatase 3) (LDP-3) (VH1-like phosphatase Z) Length = 150 Score = 35.0 bits (79), Expect = 0.24 Identities = 19/54 (35%), Positives = 26/54 (48%) Frame = -1 Query: 516 HCSAGIGRTGAYITIHNTVERILRGDQAATNLVETVGKFRSQRPGIVQTEEQYK 355 HC+ G GRTG + + ER L A + + R RPG ++T EQ K Sbjct: 94 HCALGFGRTGTMLACYLVKERGLAAGDA-------IAEIRRLRPGSIETYEQEK 140
>CDC14_YEAST (Q00684) Tyrosine-protein phosphatase CDC14 (EC 3.1.3.48)| Length = 551 Score = 34.7 bits (78), Expect = 0.31 Identities = 32/100 (32%), Positives = 40/100 (40%), Gaps = 1/100 (1%) Frame = -1 Query: 639 HTVLHIQHSTWPDHG-VPNDSSTVRKILKRLYYVGKDHPIVAHCSAGIGRTGAYITIHNT 463 H L + T PD V N I+KR GK I HC AG+GRTG I H Sbjct: 246 HLDLIFEDGTCPDLSIVKNFVGAAETIIKR---GGK---IAVHCKAGLGRTGCLIGAHLI 299 Query: 462 VERILRGDQAATNLVETVGKFRSQRPGIVQTEEQYKFCYH 343 + E +G R RPG+V +Q+ H Sbjct: 300 YTYGFTAN-------ECIGFLRFIRPGMVVGPQQHWLYLH 332
>PTP20_STYPL (P28212) Tyrosine-protein phosphatase 20 (EC 3.1.3.48) (Fragment)| Length = 116 Score = 34.7 bits (78), Expect = 0.31 Identities = 17/49 (34%), Positives = 27/49 (55%), Gaps = 4/49 (8%) Frame = -1 Query: 654 ESDRVHTVLHIQHSTWPDHGVPNDSSTV----RKILKRLYYVGKDHPIV 520 E+D V Q+ WPDH VPN +S + + +++ L +G D P+V Sbjct: 67 ENDVCGRVFQYQYINWPDHSVPNTTSNLVRMHKYVIQCLEEIGGDAPMV 115
>PTP25_STYPL (P28217) Tyrosine-protein phosphatase 25 (EC 3.1.3.48) (Fragment)| Length = 117 Score = 33.9 bits (76), Expect = 0.52 Identities = 14/47 (29%), Positives = 24/47 (51%) Frame = -1 Query: 672 VKVQHKESDRVHTVLHIQHSTWPDHGVPNDSSTVRKILKRLYYVGKD 532 V + K+ + TV + WPDHGVP +S + ++ + + KD Sbjct: 62 VSAKLKDGSVLTTVTQYHFTKWPDHGVPQTTSAIIRMHREIMKANKD 108
>PTP10_STYPL (P28202) Tyrosine-protein phosphatase 10 (EC 3.1.3.48) (Fragment)| Length = 116 Score = 33.5 bits (75), Expect = 0.68 Identities = 15/51 (29%), Positives = 25/51 (49%), Gaps = 4/51 (7%) Frame = -1 Query: 690 ELTLRSVKVQHKESDRV----HTVLHIQHSTWPDHGVPNDSSTVRKILKRL 550 + T+RS VQ + D + ++WPD GVP S + K L+++ Sbjct: 53 DYTIRSFSVQRAQGDSTMSIKRNITQYHFTSWPDFGVPKSPSGILKFLRKI 103
>PTP17_STYPL (P28209) Tyrosine-protein phosphatase 17 (EC 3.1.3.48) (Fragment)| Length = 112 Score = 33.1 bits (74), Expect = 0.89 Identities = 16/61 (26%), Positives = 30/61 (49%) Frame = -1 Query: 726 LNIKIVETRQDGELTLRSVKVQHKESDRVHTVLHIQHSTWPDHGVPNDSSTVRKILKRLY 547 + +K+ ET G+ R ++ R V+ Q WPDHG+P +S++ + K + Sbjct: 43 ITVKLRETSSCGDYVRRQFELTKNNMTR--EVVQFQFIAWPDHGIPVTTSSLFRFHKAVV 100 Query: 546 Y 544 + Sbjct: 101 F 101
>PTP23_STYPL (P28215) Tyrosine-protein phosphatase 23 (EC 3.1.3.48) (Fragment)| Length = 115 Score = 32.7 bits (73), Expect = 1.2 Identities = 15/42 (35%), Positives = 24/42 (57%), Gaps = 4/42 (9%) Frame = -1 Query: 633 VLHIQHSTWPDHGVPNDSSTV----RKILKRLYYVGKDHPIV 520 V Q+ WPDH VPN +S + + +++ L +G D P+V Sbjct: 73 VFQYQYINWPDHSVPNTTSNLVRMHKYVIQCLEEIGGDAPMV 114
>PTP16_STYPL (P28208) Tyrosine-protein phosphatase 16 (EC 3.1.3.48) (Fragment)| Length = 109 Score = 32.7 bits (73), Expect = 1.2 Identities = 17/67 (25%), Positives = 34/67 (50%) Frame = -1 Query: 720 IKIVETRQDGELTLRSVKVQHKESDRVHTVLHIQHSTWPDHGVPNDSSTVRKILKRLYYV 541 +K V+ G R +++ + ++ + H Q ++WPD+GVP +S + + K + + Sbjct: 44 LKTVDETHVGSYIKRMLEIT--SNGKMQFIHHFQFTSWPDYGVPVATSDLFRFHKAVTRI 101 Query: 540 GKDHPIV 520 PIV Sbjct: 102 KTQKPIV 108
>Y215_METJA (Q57668) Hypothetical protein MJ0215| Length = 159 Score = 32.7 bits (73), Expect = 1.2 Identities = 27/86 (31%), Positives = 40/86 (46%), Gaps = 2/86 (2%) Frame = -1 Query: 603 DHGVPN--DSSTVRKILKRLYYVGKDHPIVAHCSAGIGRTGAYITIHNTVERILRGDQAA 430 D+G+P D + +K Y+V K+ +V C G GRTG TV + G Sbjct: 74 DYGIPTVEDMDLIVDFIK--YHVSKEKEVVVSCIGGHGRTG-------TVLAVWAGLNGI 124 Query: 429 TNLVETVGKFRSQRPGIVQTEEQYKF 352 N +E V + + V+TEEQ +F Sbjct: 125 KNPIEYVRERYCE--CAVETEEQEEF 148
>PTP24_STYPL (P28216) Tyrosine-protein phosphatase 24 (EC 3.1.3.48) (Fragment)| Length = 115 Score = 32.3 bits (72), Expect = 1.5 Identities = 15/42 (35%), Positives = 23/42 (54%), Gaps = 4/42 (9%) Frame = -1 Query: 633 VLHIQHSTWPDHGVPNDSSTV----RKILKRLYYVGKDHPIV 520 V Q+ WPDH VPN +S + + +++ L G D P+V Sbjct: 73 VFQYQYINWPDHSVPNTTSNLVRMHKYVIQCLEETGSDAPMV 114
>PTP18_STYPL (P28210) Tyrosine-protein phosphatase 18 (EC 3.1.3.48) (Fragment)| Length = 115 Score = 32.3 bits (72), Expect = 1.5 Identities = 15/42 (35%), Positives = 23/42 (54%), Gaps = 4/42 (9%) Frame = -1 Query: 633 VLHIQHSTWPDHGVPNDSSTV----RKILKRLYYVGKDHPIV 520 V Q+ WPDH VPN +S + + +++ L G D P+V Sbjct: 73 VFQYQYINWPDHSVPNTTSNLVRMHKYVIQCLEETGSDAPMV 114
>MYO1D_RAT (Q63357) Myosin Id (Myosin heavy chain myr 4)| Length = 1006 Score = 32.3 bits (72), Expect = 1.5 Identities = 11/30 (36%), Positives = 19/30 (63%) Frame = -1 Query: 642 VHTVLHIQHSTWPDHGVPNDSSTVRKILKR 553 +H I TWP+H +P+D V+K+++R Sbjct: 636 LHRYKMISEFTWPNHDLPSDKEAVKKLIER 665
>MYO1D_MOUSE (Q5SYD0) Myosin Id| Length = 1006 Score = 32.3 bits (72), Expect = 1.5 Identities = 11/30 (36%), Positives = 19/30 (63%) Frame = -1 Query: 642 VHTVLHIQHSTWPDHGVPNDSSTVRKILKR 553 +H I TWP+H +P+D V+K+++R Sbjct: 636 LHRYKMISEFTWPNHDLPSDKEAVKKLIER 665
>MYO1D_HUMAN (O94832) Myosin Id| Length = 1006 Score = 32.3 bits (72), Expect = 1.5 Identities = 11/30 (36%), Positives = 19/30 (63%) Frame = -1 Query: 642 VHTVLHIQHSTWPDHGVPNDSSTVRKILKR 553 +H I TWP+H +P+D V+K+++R Sbjct: 636 LHRYKMISEFTWPNHDLPSDKEAVKKLIER 665
>SPTP_SALTI (P74851) Effector protein sptP [Includes: GTPase-activating protein| (GAP); Tyrosine-protein phosphatase (EC 3.1.3.48)] Length = 543 Score = 32.3 bits (72), Expect = 1.5 Identities = 26/120 (21%), Positives = 48/120 (40%), Gaps = 10/120 (8%) Frame = -1 Query: 717 KIVETRQDGELTLRSVKVQHKESDRVHTVLHIQHSTWPDHGVPNDSSTVRKILKRLYYVG 538 K+ Q G + ++++ E VLH+++ WPDH + + + R+ Sbjct: 405 KVSSASQGGAIDQYNMQLSCGEKRYTIPVLHVKN--WPDHQPLPSTDQLEYLADRVKNSN 462 Query: 537 KD----------HPIVAHCSAGIGRTGAYITIHNTVERILRGDQAATNLVETVGKFRSQR 388 ++ H + HC G+GRTG ++ D +NL + FR+ R Sbjct: 463 QNGAPGRSSSDKHLPMIHCLGGVGRTG------TMAAALVLKDNPHSNLEQVRADFRNSR 516
>SPTP_SALPA (Q5PEA9) Effector protein sptP [Includes: GTPase-activating protein| (GAP); Tyrosine-protein phosphatase (EC 3.1.3.48)] Length = 543 Score = 32.3 bits (72), Expect = 1.5 Identities = 26/120 (21%), Positives = 48/120 (40%), Gaps = 10/120 (8%) Frame = -1 Query: 717 KIVETRQDGELTLRSVKVQHKESDRVHTVLHIQHSTWPDHGVPNDSSTVRKILKRLYYVG 538 K+ Q G + ++++ E VLH+++ WPDH + + + R+ Sbjct: 405 KVSSASQGGAIDQYNMQLSCGEKRYTIPVLHVKN--WPDHQPLPSTDQLEYLADRVKNSN 462 Query: 537 KD----------HPIVAHCSAGIGRTGAYITIHNTVERILRGDQAATNLVETVGKFRSQR 388 ++ H + HC G+GRTG ++ D +NL + FR+ R Sbjct: 463 QNGAPGRSSSDKHLPMIHCLGGVGRTG------TMAAALVLKDNPHSNLEQVRADFRNSR 516
>PTP22_STYPL (P28214) Tyrosine-protein phosphatase 22 (EC 3.1.3.48) (Fragment)| Length = 115 Score = 32.0 bits (71), Expect = 2.0 Identities = 21/54 (38%), Positives = 29/54 (53%), Gaps = 7/54 (12%) Frame = -1 Query: 660 HKES-DRVHT--VLHIQHSTWPDHGVPNDSSTV----RKILKRLYYVGKDHPIV 520 H ES D V T V Q+ WPDH VPN +S + + +++ L G D P+V Sbjct: 61 HIESVDEVITMEVFQYQYINWPDHSVPNTTSNLVRMHKYVIQCLEETGGDAPMV 114
>PTP14_STYPL (P28206) Tyrosine-protein phosphatase 14 (EC 3.1.3.48) (Fragment)| Length = 116 Score = 31.6 bits (70), Expect = 2.6 Identities = 15/38 (39%), Positives = 19/38 (50%), Gaps = 2/38 (5%) Frame = -1 Query: 657 KESDRVHT--VLHIQHSTWPDHGVPNDSSTVRKILKRL 550 KESD + + H WPDHGVP+D V L + Sbjct: 64 KESDPPYKQIIYHHHFKVWPDHGVPSDPGGVLNFLHEI 101
>ITB5_HUMAN (P18084) Integrin beta-5 precursor| Length = 799 Score = 31.6 bits (70), Expect = 2.6 Identities = 21/65 (32%), Positives = 33/65 (50%), Gaps = 3/65 (4%) Frame = +1 Query: 373 LDDARSLGSKLPDSFHKICSSLITT*YSLYCIMDCDVST---SSPNACTAMCNNWVVFPN 543 LD+ RSLG+KL + K+ S+ +D D+S ++P T C + +FPN Sbjct: 154 LDNIRSLGTKLAEEMRKLTSNFR---LGFGSFVDKDISPFSYTAPRYQTNPCIGYKLFPN 210 Query: 544 II*SF 558 + SF Sbjct: 211 CVPSF 215
>Y3520_METJA (Q60280) Hypothetical protein MJECL20| Length = 147 Score = 31.2 bits (69), Expect = 3.4 Identities = 27/86 (31%), Positives = 38/86 (44%), Gaps = 2/86 (2%) Frame = -1 Query: 603 DHGVPN--DSSTVRKILKRLYYVGKDHPIVAHCSAGIGRTGAYITIHNTVERILRGDQAA 430 D+G+P D + +K Y+V +V C G GRTG TV I G Sbjct: 64 DYGIPTVEDMDLIVDFIK--YHVSNGREVVVSCIGGHGRTG-------TVLAIWAGLNGV 114 Query: 429 TNLVETVGKFRSQRPGIVQTEEQYKF 352 N +E V + + V+TEEQ +F Sbjct: 115 ENPIEYVRECYCE--CAVETEEQEEF 138
>SO1B3_HUMAN (Q9NPD5) Solute carrier organic anion transporter family member 1B3| (Solute carrier family 21 member 8) (Organic anion transporter 8) (Organic anion-transporting polypeptide 8) (OATP8) (Liver-specific organic anion transporter 2) (LST-2) Length = 702 Score = 30.8 bits (68), Expect = 4.4 Identities = 18/72 (25%), Positives = 31/72 (43%) Frame = +3 Query: 450 IFSLLYYGL*CKHQFSQCLHCNVQQLGGLSQHNIIFLESSLQYCCHLAHHGQAMWSAGCG 629 +F LLY+ L C+ + L ++ H ++ L YC + ++ W CG Sbjct: 420 LFQLLYFPLICESKSVAGLTLTYDGNNSVASH----VDVPLSYCNSECNCDESQWEPVCG 475 Query: 630 EQYALYLTPYVA 665 YL+P +A Sbjct: 476 NNGITYLSPCLA 487
>TPM1_DROME (P06754) Tropomyosin 1, isoforms 9A/A/B (Tropomyosin II)| (Cytoskeletal tropomyosin) Length = 339 Score = 30.8 bits (68), Expect = 4.4 Identities = 19/57 (33%), Positives = 28/57 (49%) Frame = -1 Query: 726 LNIKIVETRQDGELTLRSVKVQHKESDRVHTVLHIQHSTWPDHGVPNDSSTVRKILK 556 LN ++ E E RSV+ KE DR+ L ++ + D G D++ V ILK Sbjct: 282 LNTRLKEAEARAEFAERSVQKLQKEVDRLEDDLVLEKERYKDIGDDLDTAFVELILK 338
>AMSF_ERWAM (Q46636) Amylovoran biosynthesis protein amsF precursor| Length = 743 Score = 30.4 bits (67), Expect = 5.8 Identities = 20/65 (30%), Positives = 30/65 (46%), Gaps = 5/65 (7%) Frame = -1 Query: 687 LTLRSVKVQHKESDRV----HTVLHIQHSTWPDHG-VPNDSSTVRKILKRLYYVGKDHPI 523 + L + VQH +V I H+ W +H P D S + I+ L G +P+ Sbjct: 417 IELSNFNVQHCRQGKVLNLPRCTQSIIHNGWIEHSEFPGDLSNGQWIVDALSLEGCKNPL 476 Query: 522 VAHCS 508 +AHCS Sbjct: 477 MAHCS 481
>PTP6_STYPL (P28198) Tyrosine-protein phosphatase 6 (EC 3.1.3.48) (Fragment)| Length = 109 Score = 30.0 bits (66), Expect = 7.6 Identities = 13/53 (24%), Positives = 28/53 (52%) Frame = -1 Query: 708 ETRQDGELTLRSVKVQHKESDRVHTVLHIQHSTWPDHGVPNDSSTVRKILKRL 550 E +DG LR++K + + + + + +++WPDHGVP + ++ + Sbjct: 44 EDLKDG-YCLRTIKAE--KGNEIRYIKQFHYTSWPDHGVPKTCLEILSLINHV 93
>RPOB_DECAR (Q47JB0) DNA-directed RNA polymerase beta chain (EC 2.7.7.6) (RNAP| beta subunit) (Transcriptase beta chain) (RNA polymerase beta subunit) Length = 1427 Score = 30.0 bits (66), Expect = 7.6 Identities = 17/51 (33%), Positives = 24/51 (47%), Gaps = 2/51 (3%) Frame = -1 Query: 462 VERILRGDQAATNLVETVGKFRSQRPGIVQTEEQYKFCYHAIV--DELKDL 316 + LR D+ AT V +R RPG TEE + ++ + DE DL Sbjct: 351 ISNTLRADETATRQAARVAIYRMMRPGEPPTEEAVEILFNGLFYSDERYDL 401
>ITB5_MOUSE (O70309) Integrin beta-5 precursor| Length = 798 Score = 30.0 bits (66), Expect = 7.6 Identities = 20/65 (30%), Positives = 33/65 (50%), Gaps = 3/65 (4%) Frame = +1 Query: 373 LDDARSLGSKLPDSFHKICSSLITT*YSLYCIMDCDVST---SSPNACTAMCNNWVVFPN 543 L++ RSLG+KL + K+ S+ +D D+S ++P T C + +FPN Sbjct: 154 LENIRSLGTKLAEEMRKLTSNFR---LGFGSFVDKDISPFSYTAPRYQTNPCIGYKLFPN 210 Query: 544 II*SF 558 + SF Sbjct: 211 CVPSF 215
>DUSP_MYXVL (Q85297) Dual specificity protein phosphatase (EC 3.1.3.48) (EC| 3.1.3.16) Length = 178 Score = 29.6 bits (65), Expect = 9.9 Identities = 10/20 (50%), Positives = 15/20 (75%) Frame = -1 Query: 537 KDHPIVAHCSAGIGRTGAYI 478 K +P++ HC AG+ R+GA I Sbjct: 102 KHYPVLVHCMAGVNRSGAII 121
>CDC14_CAEEL (P81299) Probable tyrosine-protein phosphatase cdc-14 (EC 3.1.3.48)| (Cell division cycle-related protein 14) Length = 1063 Score = 29.6 bits (65), Expect = 9.9 Identities = 22/66 (33%), Positives = 27/66 (40%), Gaps = 6/66 (9%) Frame = -1 Query: 525 IVAHCSAGIGRTGAYITIHNTVERILRGDQAATNLVETVGKFRSQRPGIV------QTEE 364 + HC AG+GRTG I E L E +G R RPG V E Sbjct: 291 VAVHCKAGLGRTGTLIACWMMKEYGLTAG-------ECMGWLRVCRPGSVIGPQQPYLIE 343 Query: 363 QYKFCY 346 + KFC+ Sbjct: 344 KQKFCW 349
>PTP19_STYPL (P28211) Tyrosine-protein phosphatase 19 (EC 3.1.3.48) (Fragment)| Length = 115 Score = 29.6 bits (65), Expect = 9.9 Identities = 14/42 (33%), Positives = 22/42 (52%), Gaps = 4/42 (9%) Frame = -1 Query: 633 VLHIQHSTWPDHGVPNDSSTV----RKILKRLYYVGKDHPIV 520 V Q+ WPDH VPN +S + + +++ G D P+V Sbjct: 73 VFQYQYINWPDHCVPNTTSNLVRMHKYVIQCFEETGSDAPMV 114 Database: uniprot_sprot.fasta Posted date: May 25, 2006 5:36 PM Number of letters in database: 80,573,946 Number of sequences in database: 219,361 Lambda K H 0.318 0.135 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 102,683,910 Number of Sequences: 219361 Number of extensions: 2156616 Number of successful extensions: 5711 Number of sequences better than 10.0: 141 Number of HSP's better than 10.0 without gapping: 5330 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 5492 length of database: 80,573,946 effective HSP length: 109 effective length of database: 56,663,597 effective search space used: 7479594804 frameshift window, decay const: 50, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
