>FDFT_NICBE (P53800) Squalene synthetase (EC 2.5.1.21) (SQS) (SS)|
           (Farnesyl-diphosphate farnesyltransferase) (FPP:FPP
           farnesyltransferase)
          Length = 411

 Score =  191 bits (484), Expect = 3e-48
 Identities = 88/130 (67%), Positives = 111/130 (85%)
 Frame = -2

Query: 725 ENSEKAVQCLNDMVTNALIHAHDCLQYMSALKDNSNFRFCAIPQIMAIGTCAICYNNVKV 546
           +NS KAVQCLNDMVTNAL H  DCL YMSAL+D S FRFCAIPQ+MAIGT A+CY+N++V
Sbjct: 247 DNSAKAVQCLNDMVTNALPHVEDCLTYMSALRDPSIFRFCAIPQVMAIGTLAMCYDNIEV 306

Query: 545 FRGVVKMRRGLTARIIDETKSISDVYSAFYEFSSLLESKIDDNDPNAALTRKRVDAIKKT 366
           FRGVVKMRRGLTA++ID T++I+DVY AF++FS +L+SK+++NDPNA  T KR++ I KT
Sbjct: 307 FRGVVKMRRGLTAKVIDRTRTIADVYGAFFDFSCMLKSKVNNNDPNATKTLKRLEVILKT 366

Query: 365 CKSSGLLKRR 336
           C+ SG L +R
Sbjct: 367 CRDSGTLNKR 376

>FDFT_ARATH (P53799) Squalene synthetase (EC 2.5.1.21) (SQS) (SS)|
           (Farnesyl-diphosphate farnesyltransferase) (FPP:FPP
           farnesyltransferase)
          Length = 410

 Score =  186 bits (471), Expect = 8e-47
 Identities = 83/130 (63%), Positives = 112/130 (86%)
 Frame = -2

Query: 725 ENSEKAVQCLNDMVTNALIHAHDCLQYMSALKDNSNFRFCAIPQIMAIGTCAICYNNVKV 546
           EN+ K+VQCLN+MVTNAL+H  DCL+YM +L+D S FRFCAIPQIMAIGT A+CYNN +V
Sbjct: 249 ENTNKSVQCLNEMVTNALMHIEDCLKYMVSLRDPSIFRFCAIPQIMAIGTLALCYNNEQV 308

Query: 545 FRGVVKMRRGLTARIIDETKSISDVYSAFYEFSSLLESKIDDNDPNAALTRKRVDAIKKT 366
           FRGVVK+RRGLTA++ID TK+++DVY AFY+FS +L++K+D NDPNA+ T  R++A++K 
Sbjct: 309 FRGVVKLRRGLTAKVIDRTKTMADVYGAFYDFSCMLKTKVDKNDPNASKTLNRLEAVQKL 368

Query: 365 CKSSGLLKRR 336
           C+ +G+L+ R
Sbjct: 369 CRDAGVLQNR 378

>FDFT_HUMAN (P37268) Squalene synthetase (EC 2.5.1.21) (SQS) (SS)|
           (Farnesyl-diphosphate farnesyltransferase) (FPP:FPP
           farnesyltransferase)
          Length = 417

 Score =  110 bits (276), Expect = 3e-24
 Identities = 50/118 (42%), Positives = 80/118 (67%)
 Frame = -2

Query: 725 ENSEKAVQCLNDMVTNALIHAHDCLQYMSALKDNSNFRFCAIPQIMAIGTCAICYNNVKV 546
           EN + AVQCLN+++TNAL H  D + Y+S L++ S F FCAIPQ+MAI T A CYNN +V
Sbjct: 250 ENIDLAVQCLNELITNALHHIPDVITYLSRLRNQSVFNFCAIPQVMAIATLAACYNNQQV 309

Query: 545 FRGVVKMRRGLTARIIDETKSISDVYSAFYEFSSLLESKIDDNDPNAALTRKRVDAIK 372
           F+G VK+R+G    ++ +  ++  V +  Y++   +  +I D+DP+++ TR+ +  I+
Sbjct: 310 FKGAVKIRKGQAVTLMMDATNMPAVKAIIYQYMEEIYHRIPDSDPSSSKTRQIISTIR 367

>FDFT_MOUSE (P53798) Squalene synthetase (EC 2.5.1.21) (SQS) (SS)|
           (Farnesyl-diphosphate farnesyltransferase) (FPP:FPP
           farnesyltransferase)
          Length = 416

 Score =  107 bits (268), Expect = 3e-23
 Identities = 49/118 (41%), Positives = 80/118 (67%)
 Frame = -2

Query: 725 ENSEKAVQCLNDMVTNALIHAHDCLQYMSALKDNSNFRFCAIPQIMAIGTCAICYNNVKV 546
           EN + AVQCLN+++TN L H  D L Y+S L++ S F FCAIPQ+MAI T A CYNN +V
Sbjct: 250 ENVDVAVQCLNELITNTLQHIPDVLTYLSRLRNQSVFNFCAIPQVMAIATLAACYNNQQV 309

Query: 545 FRGVVKMRRGLTARIIDETKSISDVYSAFYEFSSLLESKIDDNDPNAALTRKRVDAIK 372
           F+GVVK+R+G    ++ +  ++  V +  Y++   +  +I ++DP+++ T++ +  I+
Sbjct: 310 FKGVVKIRKGQAVTLMMDATNMPAVKAIIYQYIEEIYHRIPNSDPSSSKTKQVISKIR 367

>FDFT_RAT (Q02769) Squalene synthetase (EC 2.5.1.21) (SQS) (SS)|
           (Farnesyl-diphosphate farnesyltransferase) (FPP:FPP
           farnesyltransferase)
          Length = 416

 Score =  105 bits (263), Expect = 1e-22
 Identities = 50/133 (37%), Positives = 87/133 (65%), Gaps = 1/133 (0%)
 Frame = -2

Query: 725 ENSEKAVQCLNDMVTNALIHAHDCLQYMSALKDNSNFRFCAIPQIMAIGTCAICYNNVKV 546
           EN + AV+CLN+++TNAL H  D + Y+S L++ S F FCAIPQ+MAI T A CYNN +V
Sbjct: 250 ENVDVAVKCLNELITNALQHIPDVITYLSRLRNQSVFNFCAIPQVMAIATLAACYNNHQV 309

Query: 545 FRGVVKMRRGLTARIIDETKSISDVYSAFYEFSSLLESKIDDNDPNAALTRKRVDAIK-K 369
           F+GVVK+R+G    ++ +  ++  V +  Y++   +  ++ ++DP+A+  ++ +  I+ +
Sbjct: 310 FKGVVKIRKGQAVTLMMDATNMPAVKAIIYQYIEEIYHRVPNSDPSASKAKQLISNIRTQ 369

Query: 368 TCKSSGLLKRRGY 330
           +  +  L+ R  Y
Sbjct: 370 SLPNCQLISRSHY 382

>FDFT_CANAL (P78589) Squalene synthetase (EC 2.5.1.21) (SQS) (SS)|
           (Farnesyl-diphosphate farnesyltransferase) (FPP:FPP
           farnesyltransferase)
          Length = 448

 Score =  105 bits (263), Expect = 1e-22
 Identities = 51/116 (43%), Positives = 73/116 (62%)
 Frame = -2

Query: 707 VQCLNDMVTNALIHAHDCLQYMSALKDNSNFRFCAIPQIMAIGTCAICYNNVKVFRGVVK 528
           V C+N++V NAL H  DCL Y+S +KD S+F FCAIPQ+MA+ T A  YNN KV  GVVK
Sbjct: 267 VSCINELVLNALGHVTDCLDYLSLVKDPSSFSFCAIPQVMAVATLAEVYNNPKVLHGVVK 326

Query: 527 MRRGLTARIIDETKSISDVYSAFYEFSSLLESKIDDNDPNAALTRKRVDAIKKTCK 360
           +R+G T R+I E++++  V   F E+  ++  K    DPN      +   I++ C+
Sbjct: 327 IRKGTTCRLILESRTLPGVVKIFKEYIQVINHKSSVRDPNYLKIGIKCGEIEQYCE 382

>FDFT_YARLI (Q9Y753) Squalene synthetase (EC 2.5.1.21) (SQS) (SS)|
           (Farnesyl-diphosphate farnesyltransferase) (FPP:FPP
           farnesyltransferase)
          Length = 445

 Score = 98.6 bits (244), Expect = 2e-20
 Identities = 48/104 (46%), Positives = 65/104 (62%)
 Frame = -2

Query: 719 SEKAVQCLNDMVTNALIHAHDCLQYMSALKDNSNFRFCAIPQIMAIGTCAICYNNVKVFR 540
           S+KA+ C +D+V NAL HA DCL Y+  + D S F FCAIPQ+MAI T  + Y N  VF+
Sbjct: 259 SKKALHCTSDLVANALGHATDCLDYLDNVTDPSTFTFCAIPQVMAIATLDLVYRNPDVFQ 318

Query: 539 GVVKMRRGLTARIIDETKSISDVYSAFYEFSSLLESKIDDNDPN 408
             VK+R+G T  +I E  ++S V   F  ++  +  K D NDPN
Sbjct: 319 KNVKLRKGTTVSLILEASNVSGVCDIFTRYARKVYKKSDPNDPN 362

>FDFT_SCHPO (P36596) Squalene synthetase (EC 2.5.1.21) (SQS) (SS)|
           (Farnesyl-diphosphate farnesyltransferase) (FPP:FPP
           farnesyltransferase)
          Length = 460

 Score = 94.0 bits (232), Expect = 4e-19
 Identities = 53/139 (38%), Positives = 77/139 (55%)
 Frame = -2

Query: 725 ENSEKAVQCLNDMVTNALIHAHDCLQYMSALKDNSNFRFCAIPQIMAIGTCAICYNNVKV 546
           +NSEKA++CL+DM  NAL HA D L Y+S LK    F FCAIPQ+MAI T A  + N  V
Sbjct: 254 DNSEKALECLSDMTANALTHATDALVYLSQLKTQEIFNFCAIPQVMAIATLAAVFRNPDV 313

Query: 545 FRGVVKMRRGLTARIIDETKSISDVYSAFYEFSSLLESKIDDNDPNAALTRKRVDAIKKT 366
           F+  VK+R+G   +II  + ++ +V   F  ++  +  K    DPN    +  ++  K  
Sbjct: 314 FQTNVKIRKGQAVQIILHSVNLKNVCDLFLRYTRDIHYKNTPKDPN--FLKISIECGKIE 371

Query: 365 CKSSGLLKRRGYDLEKSKY 309
             S  L  RR  ++ +  Y
Sbjct: 372 QVSESLFPRRFREMYEKAY 390

>FDFT_CANGA (Q9HGZ6) Squalene synthetase (EC 2.5.1.21) (SQS) (SS)|
           (Farnesyl-diphosphate farnesyltransferase) (FPP:FPP
           farnesyltransferase)
          Length = 443

 Score = 88.6 bits (218), Expect = 2e-17
 Identities = 41/106 (38%), Positives = 67/106 (63%)
 Frame = -2

Query: 725 ENSEKAVQCLNDMVTNALIHAHDCLQYMSALKDNSNFRFCAIPQIMAIGTCAICYNNVKV 546
           +N++K V C+N +V NAL H  D L Y+S++ + S+F+FCAIPQ+MAI T A  +NN +V
Sbjct: 260 KNTQKGVDCINHLVLNALTHVIDVLTYLSSIHEQSSFQFCAIPQVMAIATLAKVFNNPEV 319

Query: 545 FRGVVKMRRGLTARIIDETKSISDVYSAFYEFSSLLESKIDDNDPN 408
            R  VK+R+G T  +I  ++++      F  +   ++ ++   DPN
Sbjct: 320 LRKNVKIRKGTTCDLILNSRTLKGCVDIFQYYLRDMKQRLPVEDPN 365

>FDFT_YEAST (P29704) Squalene synthetase (EC 2.5.1.21) (SQS) (SS)|
           (Farnesyl-diphosphate farnesyltransferase) (FPP:FPP
           farnesyltransferase)
          Length = 444

 Score = 87.8 bits (216), Expect = 3e-17
 Identities = 41/106 (38%), Positives = 66/106 (62%)
 Frame = -2

Query: 725 ENSEKAVQCLNDMVTNALIHAHDCLQYMSALKDNSNFRFCAIPQIMAIGTCAICYNNVKV 546
           EN +  + C+N +V NAL H  D L Y++ + + S F+FCAIPQ+MAI T A+ +NN +V
Sbjct: 257 ENEQLGLDCINHLVLNALSHVIDVLTYLAGIHEQSTFQFCAIPQVMAIATLALVFNNREV 316

Query: 545 FRGVVKMRRGLTARIIDETKSISDVYSAFYEFSSLLESKIDDNDPN 408
             G VK+R+G T  +I +++++      F  +   ++SK+   DPN
Sbjct: 317 LHGNVKIRKGTTCYLILKSRTLRGCVEIFDYYLRDIKSKLAVQDPN 362

>FDFT_NEUCR (Q7S4Z6) Probable squalene synthetase (EC 2.5.1.21) (SQS) (SS)|
           (Farnesyl-diphosphate farnesyltransferase) (FPP:FPP
           farnesyltransferase)
          Length = 481

 Score = 85.9 bits (211), Expect = 1e-16
 Identities = 43/107 (40%), Positives = 64/107 (59%), Gaps = 1/107 (0%)
 Frame = -2

Query: 725 ENSEKAVQCLNDMVTNALIHAHDCLQYMSALKDNSNFRFCAIPQIMAIGTCAICYNNVKV 546
           EN EKA+QC ++MV NAL H  DCL YM+ ++D S F F AIPQ MAI T  + + N  +
Sbjct: 260 ENREKALQCSSEMVLNALKHTEDCLFYMAGMRDQSVFNFVAIPQAMAIATLELVFRNPAI 319

Query: 545 FRGVVKMRRGLTARI-IDETKSISDVYSAFYEFSSLLESKIDDNDPN 408
           F   VK+ +G   ++ ++ T+++  V   F  ++  +  K D  DPN
Sbjct: 320 FERNVKITKGDACQLMMESTQNLRVVCEVFRRYARRIHKKNDPRDPN 366

>FDFT_ASHGO (Q752X9) Squalene synthetase (EC 2.5.1.21) (SQS) (SS)|
           (Farnesyl-diphosphate farnesyltransferase) (FPP:FPP
           farnesyltransferase)
          Length = 441

 Score = 82.0 bits (201), Expect = 2e-15
 Identities = 38/106 (35%), Positives = 64/106 (60%)
 Frame = -2

Query: 725 ENSEKAVQCLNDMVTNALIHAHDCLQYMSALKDNSNFRFCAIPQIMAIGTCAICYNNVKV 546
           EN+   V C+N +V NAL H    L Y+++L++ S+F+FCAIPQ+MAI T A+ + N +V
Sbjct: 258 ENATAGVYCINHLVLNALGHVQHVLTYLASLREQSSFQFCAIPQVMAIATLALVFGNERV 317

Query: 545 FRGVVKMRRGLTARIIDETKSISDVYSAFYEFSSLLESKIDDNDPN 408
            +  VK+R+G T  +I ++++       F  +   +  ++   DPN
Sbjct: 318 LQTSVKIRKGTTCYLILKSRTFQGCVEIFEHYLRDIRKRLTVADPN 363

>FDFT_PICJA (O74165) Squalene synthetase (EC 2.5.1.21) (SQS) (SS)|
           (Farnesyl-diphosphate farnesyltransferase) (FPP:FPP
           farnesyltransferase)
          Length = 443

 Score = 81.3 bits (199), Expect = 3e-15
 Identities = 37/106 (34%), Positives = 64/106 (60%)
 Frame = -2

Query: 725 ENSEKAVQCLNDMVTNALIHAHDCLQYMSALKDNSNFRFCAIPQIMAIGTCAICYNNVKV 546
           EN  + + C++++V NAL H  D LQY++ +++ ++F FCAIPQ+MAI T  + + N +V
Sbjct: 257 ENQSQGLWCISELVCNALDHVIDVLQYLALVEEQTSFNFCAIPQVMAIATLELVFQNPQV 316

Query: 545 FRGVVKMRRGLTARIIDETKSISDVYSAFYEFSSLLESKIDDNDPN 408
               VK+R+G T  +I E++++      F  +   +  K   +DPN
Sbjct: 317 LTQHVKIRKGTTVSLILESRTLEGCARIFRRYLRKIHHKSHPSDPN 362

>FDFT_USTMA (Q92459) Squalene synthetase (EC 2.5.1.21) (SQS) (SS)|
           (Farnesyl-diphosphate farnesyltransferase) (FPP:FPP
           farnesyltransferase)
          Length = 572

 Score = 80.1 bits (196), Expect = 6e-15
 Identities = 40/123 (32%), Positives = 70/123 (56%)
 Frame = -2

Query: 725 ENSEKAVQCLNDMVTNALIHAHDCLQYMSALKDNSNFRFCAIPQIMAIGTCAICYNNVKV 546
           E  ++++  L+ M+ +A+ HA   L Y++ LK+ S F FCAIPQ+MAI T  + +NN  V
Sbjct: 282 ELGQRSMYVLSSMLLDAMSHATHALDYLALLKEQSVFNFCAIPQVMAIATLELMFNNPDV 341

Query: 545 FRGVVKMRRGLTARIIDETKSISDVYSAFYEFSSLLESKIDDNDPNAALTRKRVDAIKKT 366
           F+  VK+R+G+   +I    +  DV   F  +S  + +++   DPN       +  I++ 
Sbjct: 342 FKKNVKIRKGVAVGLILRAVNPRDVAYTFLHYSRKMHARLSPADPNFTRWSVELARIEQW 401

Query: 365 CKS 357
           C++
Sbjct: 402 CET 404

>TATD_ECOLI (P27859) Deoxyribonuclease tatD (EC 3.1.21.-) (DNase tatD)|
          Length = 260

 Score = 31.2 bits (69), Expect = 3.4
 Identities = 14/56 (25%), Positives = 31/56 (55%)
 Frame = -2

Query: 725 ENSEKAVQCLNDMVTNALIHAHDCLQYMSALKDNSNFRFCAIPQIMAIGTCAICYN 558
           + ++K  +  +   + A +H HD  Q+ +A ++ +     A P+++AIG C + +N
Sbjct: 43  QQAQKLARQYSSCWSTAGVHPHDSSQWQAATEE-AIIELAAQPEVVAIGECGLDFN 97

>SYC_SYNY3 (P74330) Cysteinyl-tRNA synthetase (EC 6.1.1.16) (Cysteine--tRNA|
           ligase) (CysRS)
          Length = 483

 Score = 30.0 bits (66), Expect = 7.6
 Identities = 17/55 (30%), Positives = 25/55 (45%), Gaps = 4/55 (7%)
 Frame = +3

Query: 108 TSRVHSTILHANQP----YPSAVRRYTCKTI*ARRCHEEHKRTMLTGSLAIQHAQ 260
           T R++ ++  A QP    +P  V  Y C       CH  H RT +T  L  ++ Q
Sbjct: 2   TLRLYDSLTRAKQPLQPLHPGLVTMYCCGITVYDYCHLGHARTCITWDLVRRYLQ 56


  Database: uniprot_sprot.fasta
    Posted date:  May 25, 2006  5:36 PM
  Number of letters in database: 80,573,946
  Number of sequences in database:  219,361
  
Lambda     K      H
   0.318    0.135    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 107,380,812
Number of Sequences: 219361
Number of extensions: 2297691
Number of successful extensions: 6819
Number of sequences better than 10.0: 16
Number of HSP's better than 10.0 without gapping: 6397
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 6793
length of database: 80,573,946
effective HSP length: 109
effective length of database: 56,663,597
effective search space used: 7479594804
frameshift window, decay const: 50,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)