ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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| Clone Name | rbasd19e18 |
|---|---|
| Clone Library Name | barley_pub |
>CP51_WHEAT (P93596) Cytochrome P450 51 (EC 1.14.13.70) (CYPLI) (P450-LIA1)| (Obtusifoliol 14-alpha demethylase) (Fragment) Length = 453 Score = 350 bits (899), Expect = 2e-96 Identities = 167/168 (99%), Positives = 168/168 (100%) Frame = -2 Query: 710 RHGDKIDHDILAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIV 531 RHGDKIDHDILAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIV Sbjct: 286 RHGDKIDHDILAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIV 345 Query: 530 ATSPAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQI 351 ATSPAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQI Sbjct: 346 ATSPAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQI 405 Query: 350 KAIWTHLLRNFEFELVSPFPENDWNAMVVGIKGEVMVNYKRRKLVVDN 207 KAIWTHLLRNFEFELVSPFPENDWNAMVVGIKGEVMVNYKRRKL+VDN Sbjct: 406 KAIWTHLLRNFEFELVSPFPENDWNAMVVGIKGEVMVNYKRRKLIVDN 453
>CP51_SORBI (P93846) Cytochrome P450 51 (EC 1.14.13.70) (CYPLI) (P450-LIA1)| (Obtusifoliol 14-alpha demethylase) Length = 492 Score = 340 bits (872), Expect = 3e-93 Identities = 160/168 (95%), Positives = 165/168 (98%) Frame = -2 Query: 710 RHGDKIDHDILAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIV 531 RHGDKIDHDILAEMDVLYRCIKEALRLHPPLIMLLRQSHSDF+VTT+EGKE+DIPKGHIV Sbjct: 325 RHGDKIDHDILAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFTVTTKEGKEYDIPKGHIV 384 Query: 530 ATSPAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQI 351 ATSP+FANRLPHI+KNPDSYDPDRF GREEDK AGAFSYISFGGGRHGCLGEPFAYLQI Sbjct: 385 ATSPSFANRLPHIYKNPDSYDPDRFGPGREEDKAAGAFSYISFGGGRHGCLGEPFAYLQI 444 Query: 350 KAIWTHLLRNFEFELVSPFPENDWNAMVVGIKGEVMVNYKRRKLVVDN 207 KAIWTHLLRNFEFELVSPFPENDWNAMVVGIKGEVMVNYKRRKLVVDN Sbjct: 445 KAIWTHLLRNFEFELVSPFPENDWNAMVVGIKGEVMVNYKRRKLVVDN 492
>CP51_MYCVN (Q5IZM4) Cytochrome P450 51 (EC 1.14.13.70) (CYPLI) (P450-LIA1)| (Sterol 14-alpha demethylase) (Lanosterol 14-alpha demethylase) (P450-14DM) Length = 452 Score = 132 bits (331), Expect = 1e-30 Identities = 71/163 (43%), Positives = 101/163 (61%), Gaps = 3/163 (1%) Frame = -2 Query: 704 GDKIDHDILAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVAT 525 G ++ L ++ L +KE LRLHPPLI+L+R + +F V + I KG +VA Sbjct: 294 GQEVSFHALRQIPSLDNALKETLRLHPPLIILMRVAQDEFEVAG-----YPIHKGQMVAA 348 Query: 524 SPAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKA 345 SPA +NR+P F NPD +DPDR+ R+ED + +++I FG G+H C+G FA +QIKA Sbjct: 349 SPAISNRIPEDFPNPDDFDPDRYEKPRQEDLI-NRWTWIPFGAGKHRCVGAAFAQMQIKA 407 Query: 344 IWTHLLRNFEFELVSPFPE---NDWNAMVVGIKGEVMVNYKRR 225 I++ LLR +EFE+ P PE ND + MVV + V Y+RR Sbjct: 408 IFSVLLREYEFEMAQP-PESYQNDHSKMVVQLARPAKVRYRRR 449
>CP51_MYCTU (P0A512) Cytochrome P450 51 (EC 1.14.13.70) (CYPLI) (P450-LIA1)| (Sterol 14-alpha demethylase) (Lanosterol 14-alpha demethylase) (P450-14DM) Length = 451 Score = 117 bits (293), Expect = 3e-26 Identities = 67/163 (41%), Positives = 96/163 (58%), Gaps = 3/163 (1%) Frame = -2 Query: 704 GDKIDHDILAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVAT 525 G + L ++ L +KE LRLHPPLI+L+R + +F V I +G +VA Sbjct: 293 GRSVSFHALRQIPQLENVLKETLRLHPPLIILMRVAKGEFEVQGHR-----IHEGDLVAA 347 Query: 524 SPAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKA 345 SPA +NR+P F +P + P R+ R+ED + +++I FG GRH C+G FA +QIKA Sbjct: 348 SPAISNRIPEDFPDPHDFVPARYEQPRQED-LLNRWTWIPFGAGRHRCVGAAFAIMQIKA 406 Query: 344 IWTHLLRNFEFELVSPFPE---NDWNAMVVGIKGEVMVNYKRR 225 I++ LLR +EFE+ P PE ND + MVV + V Y+RR Sbjct: 407 IFSVLLREYEFEMAQP-PESYRNDHSKMVVQLAQPACVRYRRR 448
>CP51_MYCBO (P0A513) Cytochrome P450 51 (EC 1.14.13.70) (CYPLI) (P450-LIA1)| (Sterol 14-alpha demethylase) (Lanosterol 14-alpha demethylase) (P450-14DM) Length = 451 Score = 117 bits (293), Expect = 3e-26 Identities = 67/163 (41%), Positives = 96/163 (58%), Gaps = 3/163 (1%) Frame = -2 Query: 704 GDKIDHDILAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVAT 525 G + L ++ L +KE LRLHPPLI+L+R + +F V I +G +VA Sbjct: 293 GRSVSFHALRQIPQLENVLKETLRLHPPLIILMRVAKGEFEVQGHR-----IHEGDLVAA 347 Query: 524 SPAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKA 345 SPA +NR+P F +P + P R+ R+ED + +++I FG GRH C+G FA +QIKA Sbjct: 348 SPAISNRIPEDFPDPHDFVPARYEQPRQED-LLNRWTWIPFGAGRHRCVGAAFAIMQIKA 406 Query: 344 IWTHLLRNFEFELVSPFPE---NDWNAMVVGIKGEVMVNYKRR 225 I++ LLR +EFE+ P PE ND + MVV + V Y+RR Sbjct: 407 IFSVLLREYEFEMAQP-PESYRNDHSKMVVQLAQPACVRYRRR 448
>CP51A_PONPY (Q5RE72) Cytochrome P450 51A1 (EC 1.14.13.70) (CYPLI) (P450LI)| (Sterol 14-alpha demethylase) (Lanosterol 14-alpha demethylase) (LDM) (P450-14DM) (P45014DM) Length = 503 Score = 107 bits (267), Expect = 4e-23 Identities = 59/159 (37%), Positives = 96/159 (60%), Gaps = 2/159 (1%) Frame = -2 Query: 695 IDHDILAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPA 516 + +D L ++++L RCIKE LRL PP+++++R + + +V + IP GH V SP Sbjct: 352 LTYDQLKDLNLLDRCIKETLRLRPPIMIMMRMARTPQTVAG-----YTIPPGHQVCVSPT 406 Query: 515 FANRLPHIFKNPDSYDPDRFAAGREEDKVAGA-FSYISFGGGRHGCLGEPFAYLQIKAIW 339 RL + ++PDR+ +++ +G F+Y+ FG GRH C+GE FAY+QIK IW Sbjct: 407 VNQRLKDSWVERLDFNPDRYL---QDNPASGEKFAYVPFGAGRHRCIGENFAYVQIKTIW 463 Query: 338 THLLRNFEFELVSP-FPENDWNAMVVGIKGEVMVNYKRR 225 + +LR +EF+L+ FP ++ M+ + V + YKRR Sbjct: 464 STMLRLYEFDLIDGYFPTVNYTTMIHTPENPV-IRYKRR 501
>CP51A_HUMAN (Q16850) Cytochrome P450 51A1 (EC 1.14.13.70) (CYPLI) (P450LI)| (Sterol 14-alpha demethylase) (Lanosterol 14-alpha demethylase) (LDM) (P450-14DM) (P45014DM) Length = 503 Score = 107 bits (267), Expect = 4e-23 Identities = 59/159 (37%), Positives = 96/159 (60%), Gaps = 2/159 (1%) Frame = -2 Query: 695 IDHDILAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPA 516 + +D L ++++L RCIKE LRL PP+++++R + + +V + IP GH V SP Sbjct: 352 LTYDQLKDLNLLDRCIKETLRLRPPIMIMMRMARTPQTVAG-----YTIPPGHQVCVSPT 406 Query: 515 FANRLPHIFKNPDSYDPDRFAAGREEDKVAGA-FSYISFGGGRHGCLGEPFAYLQIKAIW 339 RL + ++PDR+ +++ +G F+Y+ FG GRH C+GE FAY+QIK IW Sbjct: 407 VNQRLKDSWVERLDFNPDRYL---QDNPASGEKFAYVPFGAGRHRCIGENFAYVQIKTIW 463 Query: 338 THLLRNFEFELVSP-FPENDWNAMVVGIKGEVMVNYKRR 225 + +LR +EF+L+ FP ++ M+ + V + YKRR Sbjct: 464 STMLRLYEFDLIDGYFPTVNYTTMIHTPENPV-IRYKRR 501
>CP51A_BOVIN (Q4PJW3) Cytochrome P450 51A1 (EC 1.14.13.70) (CYPLI) (P450LI)| (Sterol 14-alpha demethylase) (Lanosterol 14-alpha demethylase) (LDM) (P450-14DM) (P45014DM) Length = 502 Score = 106 bits (265), Expect = 6e-23 Identities = 59/159 (37%), Positives = 94/159 (59%), Gaps = 2/159 (1%) Frame = -2 Query: 695 IDHDILAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPA 516 + +D L ++++L RCIKE LRL PP++ ++R + + +V + IP GH V SP Sbjct: 351 LTYDQLKDLNLLDRCIKETLRLRPPIMTMMRLAKTPLTVAG-----YTIPPGHQVCVSPT 405 Query: 515 FANRLPHIFKNPDSYDPDRFAAGREEDKVAGA-FSYISFGGGRHGCLGEPFAYLQIKAIW 339 RL + ++PDR+ E+ +G F+Y+ FG GRH C+GE FAY+QIK IW Sbjct: 406 VNQRLKDSWVERLDFNPDRYL---EDSPASGEKFAYVPFGAGRHRCIGENFAYVQIKTIW 462 Query: 338 THLLRNFEFELVSP-FPENDWNAMVVGIKGEVMVNYKRR 225 + +LR +EF+L+ FP ++ M + + ++ YKRR Sbjct: 463 STMLRLYEFDLIDGYFPTVNYTTM-IHTPEKPIIRYKRR 500
>CP51A_PIG (O46420) Cytochrome P450 51A1 (EC 1.14.13.70) (CYPLI) (P450LI)| (Sterol 14-alpha demethylase) (Lanosterol 14-alpha demethylase) (LDM) (P450-14DM) Length = 503 Score = 106 bits (264), Expect = 8e-23 Identities = 59/159 (37%), Positives = 95/159 (59%), Gaps = 2/159 (1%) Frame = -2 Query: 695 IDHDILAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPA 516 + +D L ++++L RCIKE LRL PP++ ++R + + +V + IP GH V SP Sbjct: 352 LTYDQLKDLNLLDRCIKETLRLRPPIMTMMRMAKTPQTVAG-----YTIPPGHQVCVSPT 406 Query: 515 FANRLPHIFKNPDSYDPDRFAAGREEDKVAGA-FSYISFGGGRHGCLGEPFAYLQIKAIW 339 RL + ++PDR+ +++ +G F+Y+ FG GRH C+GE FAY+QIK IW Sbjct: 407 VNQRLKDSWVERLDFNPDRYL---QDNPASGEKFAYVPFGAGRHRCIGENFAYVQIKTIW 463 Query: 338 THLLRNFEFELVSP-FPENDWNAMVVGIKGEVMVNYKRR 225 + +LR +EF+L+ FP ++ M+ + V + YKRR Sbjct: 464 STMLRLYEFDLIDGYFPTVNYTTMIHTPENPV-IRYKRR 501
>CP51A_RAT (Q64654) Cytochrome P450 51A1 (EC 1.14.13.70) (CYPLI) (P450LI)| (Sterol 14-alpha demethylase) (Lanosterol 14-alpha demethylase) (LDM) (P450-14DM) Length = 503 Score = 105 bits (262), Expect = 1e-22 Identities = 58/159 (36%), Positives = 96/159 (60%), Gaps = 2/159 (1%) Frame = -2 Query: 695 IDHDILAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPA 516 + ++ L ++++L RCIKE LRL PP++ ++R + + +V + IP GH V SP Sbjct: 352 LTYEQLKDLNLLDRCIKETLRLRPPIMTMMRMAKTPQTVAG-----YTIPPGHQVCVSPT 406 Query: 515 FANRLPHIFKNPDSYDPDRFAAGREEDKVAGA-FSYISFGGGRHGCLGEPFAYLQIKAIW 339 RL + ++PDR+ +++ +G F+Y+ FG GRH C+GE FAY+QIK IW Sbjct: 407 VNQRLKDSWVERLDFNPDRYL---QDNPASGEKFAYVPFGAGRHRCIGENFAYVQIKTIW 463 Query: 338 THLLRNFEFELVSP-FPENDWNAMVVGIKGEVMVNYKRR 225 + +LR +EF+L++ FP ++ M+ + V + YKRR Sbjct: 464 STMLRLYEFDLINGYFPSVNYTTMIHTPENPV-IRYKRR 501
>CP51_USTMA (P49602) Cytochrome P450 51 (EC 1.14.13.70) (CYPLI) (P450-LIA1)| (Sterol 14-alpha demethylase) (Lanosterol 14-alpha demethylase) (P450-14DM) Length = 561 Score = 93.2 bits (230), Expect = 7e-19 Identities = 58/156 (37%), Positives = 80/156 (51%), Gaps = 27/156 (17%) Frame = -2 Query: 650 IKEALRLHPPLIMLLRQSHSDFSVT----------TREGKEFDIPKGHIVATSPAFANRL 501 +KE LRLHPPL ++R SD +V + + IPKGH + +P + Sbjct: 385 VKETLRLHPPLHSIMRYVKSDLAVPPTLSSPTSTKSEPDAHYVIPKGHYIMAAPGVSQVD 444 Query: 500 PHIFKNPDSYDPDRF-----AAGRE---EDKVAGAFS---------YISFGGGRHGCLGE 372 P I+K+ D +DP R+ AA + EDK F Y+ FG GRH C+GE Sbjct: 445 PQIWKSSDQFDPHRWLDATTAAAMQDSGEDKQDFGFGMISTGANSPYLPFGAGRHRCIGE 504 Query: 371 PFAYLQIKAIWTHLLRNFEFELVSPFPENDWNAMVV 264 FAYLQI I +R F++ L S FP+ D+ +MVV Sbjct: 505 QFAYLQIGVILATFVRIFKWHLDSKFPDPDYQSMVV 540
>CP51_CUNEL (Q9UVC3) Cytochrome P450 51 (EC 1.14.13.70) (CYPLI) (P450-LIA1)| (Sterol 14-alpha demethylase) (Lanosterol 14-alpha demethylase) (P450-14DM) Length = 512 Score = 88.6 bits (218), Expect = 2e-17 Identities = 55/174 (31%), Positives = 87/174 (50%), Gaps = 19/174 (10%) Frame = -2 Query: 686 DILAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFAN 507 D L ++ +L I+E LRLHPP+ ++R+ +D V + G E IPKG+ + +P Sbjct: 341 DNLKDLPLLEAAIRETLRLHPPIFQMMRRVVADKIVYEKNGME--IPKGNFICAAPGVTQ 398 Query: 506 RLPHIFKNPDSYDPDRFAAGREE------------DKVAGAFS------YISFGGGRHGC 381 P F P +Y+P R+ + D GA ++ FG GRH C Sbjct: 399 VDPTYFNEPTTYNPYRWIEKTDPVHQLEQGDDANIDYGFGAVGISSKSPFLPFGAGRHRC 458 Query: 380 LGEPFAYLQIKAIWTHLLRNFEFEL-VSPFPENDWNAMVVGIKGEVMVNYKRRK 222 +GE F YLQ+K + + +R F+F+L P++D+ +MVV + V Y R+ Sbjct: 459 IGEQFGYLQLKTVISTFIRTFDFDLDGKSVPKSDYTSMVVVPEHTAKVRYTWRE 512
>CP4CU_BLAGE (Q964T1) Cytochrome P450 4c21 (EC 1.14.14.1) (CYPIVC21)| Length = 501 Score = 86.7 bits (213), Expect = 7e-17 Identities = 47/127 (37%), Positives = 72/127 (56%) Frame = -2 Query: 680 LAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFANRL 501 L M+ L R IKE+LRLHP +I +R++H DF + + IP G + S F +R Sbjct: 355 LNNMNYLERVIKESLRLHPSVIYFVREAHQDFELGG-----YTIPAGTNIDFSVPFIHRN 409 Query: 500 PHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRN 321 P IF NP ++PD F R ++ ++YI F G C+G+ FA L+ K + ++LLR+ Sbjct: 410 PEIFPNPRCFNPDNFLPDRVVNR--HPYAYIPFSAGPRNCIGQRFALLEEKVVLSYLLRH 467 Query: 320 FEFELVS 300 + F V+ Sbjct: 468 YRFRTVN 474
>CP51_ASHGO (Q759W0) Cytochrome P450 51 (EC 1.14.13.70) (CYPLI) (P450-LIA1)| (Sterol 14-alpha demethylase) (Lanosterol 14-alpha demethylase) (P450-14DM) Length = 529 Score = 86.3 bits (212), Expect = 9e-17 Identities = 55/175 (31%), Positives = 88/175 (50%), Gaps = 17/175 (9%) Frame = -2 Query: 698 KIDHDILAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSP 519 ++ +++L EM +L + IKE LR+H PL L R+ D V + IPK H V SP Sbjct: 352 ELTYELLQEMPLLNQVIKETLRMHHPLHSLFRKVTRDMPVPNTS---YVIPKDHYVLASP 408 Query: 518 AFANRLPHIFKNPDSYDPDRF--------AAGREEDKVAGAFS------YISFGGGRHGC 381 F + F N ++P R+ + G + D GA S Y+ FGGGRH C Sbjct: 409 GFCHLSEEYFPNAKEFNPHRWDNDAASSVSTGEKVDYGFGAISKGVSSPYLPFGGGRHRC 468 Query: 380 LGEPFAYLQIKAIWTHLLRNFEFEL---VSPFPENDWNAMVVGIKGEVMVNYKRR 225 +GE FAY+Q+ I++ ++R+ ++ + P D+ +MV + ++RR Sbjct: 469 IGEGFAYMQLGTIFSVVVRSMKWHFPADMKGVPNPDFTSMVTLPSEPCRIAWERR 523
>CP136_MYCTU (P95099) Putative cytochrome P450 136 (EC 1.14.-.-)| Length = 492 Score = 84.7 bits (208), Expect = 2e-16 Identities = 55/160 (34%), Positives = 86/160 (53%), Gaps = 3/160 (1%) Frame = -2 Query: 710 RHGD-KIDHDILAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHI 534 RHGD +D + L +++ L + E++RL P+ +RQ+ D + + +PKG Sbjct: 335 RHGDGPLDIESLEQLESLDLVMNESIRLVTPVQWAMRQTVRDTELLG-----YYLPKGTN 389 Query: 533 VATSPAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQ 354 V P +RLP I+ +P ++DP+RF R E K +++ FGGG H C+G F L+ Sbjct: 390 VIAYPGMNHRLPEIWTDPLTFDPERFTEPRNEHK-RHRYAFTPFGGGVHKCIGMVFDQLE 448 Query: 353 IKAIWTHLLRNFEFELVSP--FPENDWNAMVVGIKGEVMV 240 IK I LLR + EL P P D++AM + + G +V Sbjct: 449 IKTILHRLLRRYRLELSRPDYQPRWDYSAMPIPMDGMPIV 488
>CP51_CANAL (P10613) Cytochrome P450 51 (EC 1.14.13.70) (CYPLI) (P450-LIA1)| (Sterol 14-alpha demethylase) (Lanosterol 14-alpha demethylase) (P450-14DM) Length = 528 Score = 81.6 bits (200), Expect = 2e-15 Identities = 51/163 (31%), Positives = 80/163 (49%), Gaps = 19/163 (11%) Frame = -2 Query: 695 IDHDILAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPA 516 + ++ L ++ + IKE LR+H PL + R+ + + + +PKGH V SP Sbjct: 351 LTYEDLQKLPSVNNTIKETLRMHMPLHSIFRKVTNPLRIPETN---YIVPKGHYVLVSPG 407 Query: 515 FANRLPHIFKNPDSYDPDR------------FAAGREEDKVAGAFS------YISFGGGR 390 +A+ F NP+ +DP R F + E D G S Y+ FGGGR Sbjct: 408 YAHTSERYFDNPEDFDPTRWDTAAAKANSVSFNSSDEVDYGFGKVSKGVSSPYLPFGGGR 467 Query: 389 HGCLGEPFAYLQIKAIWTHLLRNFEFELVS-PFPENDWNAMVV 264 H C+GE FAY+Q+ I T + N + + P+ D+++MVV Sbjct: 468 HRCIGEQFAYVQLGTILTTFVYNLRWTIDGYKVPDPDYSSMVV 510
>CP51_YEAST (P10614) Cytochrome P450 51 (EC 1.14.13.70) (CYPLI) (P450-LIA1)| (Sterol 14-alpha demethylase) (Lanosterol 14-alpha demethylase) (P450-14DM) Length = 530 Score = 80.1 bits (196), Expect = 6e-15 Identities = 53/174 (30%), Positives = 83/174 (47%), Gaps = 16/174 (9%) Frame = -2 Query: 698 KIDHDILAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSP 519 ++ +D+L EM +L + IKE LR+H PL L R+ D V + IP G+ V SP Sbjct: 354 ELTYDLLQEMPLLNQTIKETLRMHHPLHSLFRKVMKDMHVPNTS---YVIPAGYHVLVSP 410 Query: 518 AFANRLPHIFKNPDSYDPDR--------FAAGREEDKVAGAFS------YISFGGGRHGC 381 + + F N ++ R ++ G E D GA S Y+ FGGGRH C Sbjct: 411 GYTHLRDEYFPNAHQFNIHRWNKDSASSYSVGEEVDYGFGAISKGVSSPYLPFGGGRHRC 470 Query: 380 LGEPFAYLQIKAIWTHLLRNFEFELV--SPFPENDWNAMVVGIKGEVMVNYKRR 225 +GE FAY Q+ + + +R ++ P D+ +MV G + +++R Sbjct: 471 IGEHFAYCQLGVLMSIFIRTLKWHYPEGKTVPPPDFTSMVTLPTGPAKIIWEKR 524
>CP51_SCHPO (Q09736) Probable cytochrome P450 51 (EC 1.14.13.70) (CYPLI)| (P450-LIA1) (Sterol 14-alpha demethylase) (Lanosterol 14-alpha demethylase) (P450-14DM) Length = 495 Score = 79.7 bits (195), Expect = 8e-15 Identities = 49/171 (28%), Positives = 80/171 (46%), Gaps = 13/171 (7%) Frame = -2 Query: 698 KIDHDILAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSP 519 ++ D +M +L I+E LRLHPP+ +R+ D V G + IP + + +P Sbjct: 327 ELKFDQYKDMPLLNYVIQETLRLHPPIHSHMRKVKRDLPVP---GSKIVIPANNYLLAAP 383 Query: 518 AFANRLPHIFKNPDSYDPDRFAAGREEDKVA-------------GAFSYISFGGGRHGCL 378 F + +DP R+ ED+ A A Y+ FG GRH C+ Sbjct: 384 GLTATEEEYFTHATDFDPKRWNDRVNEDENAEQIDYGYGLVTKGAASPYLPFGAGRHRCI 443 Query: 377 GEPFAYLQIKAIWTHLLRNFEFELVSPFPENDWNAMVVGIKGEVMVNYKRR 225 GE FAY+ + I + + ++ + L+ P D+++MV G V + +KRR Sbjct: 444 GEQFAYMHLSTIISKFVHDYTWTLIGKVPNVDYSSMVALPLGPVKIAWKRR 494
>CP51_CANTR (P14263) Cytochrome P450 51 (EC 1.14.13.70) (CYPLI) (P450-LIA1)| (Sterol 14-alpha demethylase) (Lanosterol 14-alpha demethylase) (P450-14DM) Length = 528 Score = 79.0 bits (193), Expect = 1e-14 Identities = 50/162 (30%), Positives = 82/162 (50%), Gaps = 19/162 (11%) Frame = -2 Query: 695 IDHDILAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPA 516 + ++ L ++ ++ IKE LR+H PL + R+ + V + + IPKGH V S Sbjct: 351 LTYEDLQKLPLVNNTIKETLRMHMPLHSIFRKVMNPLRVPNTK---YVIPKGHYVLVSAG 407 Query: 515 FANRLPHIFKNPDSYDPDRFAAG---------REEDKVAGAFS---------YISFGGGR 390 +A+ F++P+ ++P R+ + ED V F Y+ FGGGR Sbjct: 408 YAHTSDRWFEHPEHFNPRRWESDDTKASAVSFNSEDTVDYGFGKISKGVSSPYLPFGGGR 467 Query: 389 HGCLGEPFAYLQIKAIWTHLLRNFEFEL-VSPFPENDWNAMV 267 H C+GE FAY+Q+ I T + NF++ L P+ D+ +MV Sbjct: 468 HRCIGEQFAYVQLGTILTTYIYNFKWRLNGDKVPDVDYQSMV 509
>CP4D1_DROSI (O16805) Cytochrome P450 4d1 (EC 1.14.-.-) (CYPIVD1)| Length = 512 Score = 78.6 bits (192), Expect = 2e-14 Identities = 41/136 (30%), Positives = 74/136 (54%) Frame = -2 Query: 695 IDHDILAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPA 516 + +++L ++ + C+KE LR++P + +L R+ D + + IP G + SP Sbjct: 358 VSYELLNQLHYVDLCVKETLRMYPSVPLLGRKVLEDCEINGKL-----IPAGTNIGISPL 412 Query: 515 FANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWT 336 + R +F P+S+ P+RF +K+ ++YI F G C+G+ FA L+IKAI Sbjct: 413 YLGRREELFSEPNSFKPERFDVVTTAEKL-NPYAYIPFSAGPRNCIGQKFAMLEIKAIVA 471 Query: 335 HLLRNFEFELVSPFPE 288 ++LR++E + V E Sbjct: 472 NVLRHYEVDFVGDSSE 487
>CP4D1_DROME (P33269) Cytochrome P450 4d1 (EC 1.14.-.-) (CYPIVD1)| Length = 512 Score = 78.6 bits (192), Expect = 2e-14 Identities = 41/136 (30%), Positives = 74/136 (54%) Frame = -2 Query: 695 IDHDILAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPA 516 + +++L ++ + C+KE LR++P + +L R+ D + + IP G + SP Sbjct: 358 VSYELLNQLHYVDLCVKETLRMYPSVPLLGRKVLEDCEINGKL-----IPAGTNIGISPL 412 Query: 515 FANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWT 336 + R +F P+S+ P+RF +K+ ++YI F G C+G+ FA L+IKAI Sbjct: 413 YLGRREELFSEPNSFKPERFDVVTTAEKL-NPYAYIPFSAGPRNCIGQKFAMLEIKAIVA 471 Query: 335 HLLRNFEFELVSPFPE 288 ++LR++E + V E Sbjct: 472 NVLRHYEVDFVGDSSE 487
>C4D10_DROMT (O18596) Cytochrome P450 4d10 (EC 1.14.-.-) (CYPIVD10)| Length = 513 Score = 77.4 bits (189), Expect = 4e-14 Identities = 47/159 (29%), Positives = 82/159 (51%), Gaps = 2/159 (1%) Frame = -2 Query: 695 IDHDILAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPA 516 + +D+L ++ + CIKE LR++P + +L R+ + + + IP G + SP Sbjct: 359 VTYDLLNNLNYMDLCIKETLRMYPSVPLLGRKVLQECEINGKI-----IPAGTNIGISPL 413 Query: 515 FANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWT 336 F R I P+++ P+RF +K+ +YI F G C+G+ FA L+IKAI Sbjct: 414 FLGRSEDISSEPNTFKPERFDVVTSAEKL-NPHAYIPFSAGPRNCIGQKFAMLEIKAIAA 472 Query: 335 HLLRNFEFELVSPFPEND--WNAMVVGIKGEVMVNYKRR 225 ++LR++E E V E+ +++ K +M K+R Sbjct: 473 NVLRHYEIEFVGNAEESPVLIAELILRTKDPLMFKLKKR 511
>C4G15_DROME (Q9VYY4) Cytochrome P450 4g15 (EC 1.14.-.-) (CYPIVG15)| Length = 574 Score = 77.0 bits (188), Expect = 5e-14 Identities = 38/132 (28%), Positives = 73/132 (55%) Frame = -2 Query: 674 EMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFANRLPH 495 EM L RC+ E LR++PP+ ++ R+ D + + + IP+G V + +R P Sbjct: 427 EMKYLERCLMETLRMYPPVPLIARELQEDLKLNSGN---YVIPRGATVTVATVLLHRNPK 483 Query: 494 IFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFE 315 ++ NP+ +DPD F R+ ++ ++++ F G C+G +A L++K + + +LRN Sbjct: 484 VYANPNVFDPDNFLPERQANR--HYYAFVPFSAGPRSCVGRKYAMLKLKILLSTILRN-- 539 Query: 314 FELVSPFPENDW 279 + + S E+D+ Sbjct: 540 YRVYSDLTESDF 551
>CP312_DROME (Q9VVN6) Probable cytochrome P450 312a1 (EC 1.14.-.-) (CYPCCCXIIA1)| Length = 510 Score = 76.6 bits (187), Expect = 7e-14 Identities = 44/131 (33%), Positives = 70/131 (53%) Frame = -2 Query: 701 DKIDHDILAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATS 522 + I + + +++ L CIKE LR++P + R++ ++ ++ +F IPKG V S Sbjct: 356 EPISIEQVRQLEFLEACIKETLRMYPSGPLTARKATANCTIN-----DFFIPKGSDVIIS 410 Query: 521 PAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAI 342 P + R F +P + PDR+A G E A F I F G C+G+ +A + +K + Sbjct: 411 PIYMGRCKDFFPDPMVFKPDRWAIGAEPKIEATTF--IPFMAGARSCMGQRYAMVMLKMV 468 Query: 341 WTHLLRNFEFE 309 HLLRNF FE Sbjct: 469 LAHLLRNFLFE 479
>CP26A_HUMAN (O43174) Cytochrome P450 26A1 (EC 1.14.-.-) (Retinoic| acid-metabolizing cytochrome) (P450 retinoic acid-inactivating 1) (P450RAI) (hP450RAI) (Retinoic acid 4-hydroxylase) Length = 497 Score = 75.5 bits (184), Expect = 2e-13 Identities = 47/137 (34%), Positives = 74/137 (54%) Frame = -2 Query: 701 DKIDHDILAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATS 522 +K+D +IL ++ + IKE LRL+PP+ R ++ T E + IPKG V S Sbjct: 343 NKLDMEILEQLKYIGCVIKETLRLNPPVPGGFR-----VALKTFELNGYQIPKGWNVIYS 397 Query: 521 PAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAI 342 + + IF N + ++PDRF ED A FS+I FGGG C+G+ FA + +K Sbjct: 398 ICDTHDVAEIFTNKEEFNPDRFMLPHPED--ASRFSFIPFGGGLRSCVGKEFAKILLKIF 455 Query: 341 WTHLLRNFEFELVSPFP 291 L R+ +++L++ P Sbjct: 456 TVELARHCDWQLLNGPP 472
>CP4F5_RAT (P51870) Cytochrome P450 4F5 (EC 1.14.14.1) (CYPIVF5)| Length = 526 Score = 75.1 bits (183), Expect = 2e-13 Identities = 46/131 (35%), Positives = 71/131 (54%) Frame = -2 Query: 710 RHGDKIDHDILAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIV 531 R ++I+ D LA++ L CIKE+LRLHPP I LLR+ D + +G+ IPKG+I Sbjct: 367 REPEEIEWDDLAQLPFLTMCIKESLRLHPPAIDLLRRCTQD--IVLPDGRV--IPKGNIC 422 Query: 530 ATSPAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQI 351 S + P ++ +P+ +DP RF + E + S+I F G C+G+ FA ++ Sbjct: 423 VISIFGIHHNPSVWPDPEVFDPFRFDS--ENRQKRSPLSFIPFSAGPRNCIGQTFAMNEM 480 Query: 350 KAIWTHLLRNF 318 K + L F Sbjct: 481 KVVVALTLLRF 491
>CP51_CANGA (P50859) Cytochrome P450 51 (EC 1.14.13.70) (CYPLI) (P450-LIA1)| (Sterol 14-alpha-demethylase) (Lanosterol 14-alpha demethylase) (P450-14DM) Length = 533 Score = 74.7 bits (182), Expect = 3e-13 Identities = 50/176 (28%), Positives = 84/176 (47%), Gaps = 18/176 (10%) Frame = -2 Query: 698 KIDHDILAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSP 519 ++ +D L M +L + IKE LRLH PL L R+ D ++ + +P+ + V SP Sbjct: 355 ELTYDDLQNMPLLNQMIKETLRLHHPLHSLFRKVMRDVAIPNTS---YVVPRDYHVLVSP 411 Query: 518 AFANRLPHIFKNPDSYDPDRF---------AAGREEDKVAGAFS------YISFGGGRHG 384 + + F P+ ++ R+ A G E D GA S Y+ FGGGRH Sbjct: 412 GYTHLQEEFFPKPNEFNIHRWDGDAASSSAAGGDEVDYGFGAISKGVSSPYLPFGGGRHR 471 Query: 383 CLGEPFAYLQIKAIWTHLLRNFEFELVS---PFPENDWNAMVVGIKGEVMVNYKRR 225 C+GE FAY Q+ + + +R ++ + P +D+ +MV + +++R Sbjct: 472 CIGELFAYCQLGVLMSIFIRTMKWRYPTEGETVPPSDFTSMVTLPTAPAKIYWEKR 527
>CP51_PENIT (Q12664) Cytochrome P450 51 (EC 1.14.13.70) (CYPLI) (P450-LIA1)| (Sterol 14-alpha demethylase) (Eburicol 14-alpha-demethylase) (P450-14DM) Length = 515 Score = 73.9 bits (180), Expect = 4e-13 Identities = 48/151 (31%), Positives = 77/151 (50%), Gaps = 16/151 (10%) Frame = -2 Query: 674 EMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFANRLPH 495 ++ +L IKE LRLH + L+R+ + V G +F +P H + +SP R Sbjct: 352 KLPLLRNVIKETLRLHSSIHTLMRKVKNPMPVP---GTDFVVPPSHTLLSSPGVTARDER 408 Query: 494 IFKNPDSYDPDRFAAGREEDKVA-------GAFS------YISFGGGRHGCLGEPFAYLQ 354 F++P +DP R+ + E + + GA S Y+ FG GRH C+GE FAYL Sbjct: 409 HFRDPLRWDPHRWESRVEVEDSSDTVDYGYGAVSKGTRSPYLPFGAGRHRCIGEKFAYLN 468 Query: 353 IKAIWTHLLRNFEF---ELVSPFPENDWNAM 270 ++ I L+R F F E + P+ D++++ Sbjct: 469 LEVIVATLVREFRFFNPEGMEGVPDTDYSSL 499
>CP4D2_DROME (Q27589) Cytochrome P450 4d2 (EC 1.14.-.-) (CYPIVD2)| Length = 501 Score = 73.6 bits (179), Expect = 6e-13 Identities = 47/143 (32%), Positives = 71/143 (49%) Frame = -2 Query: 680 LAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFANRL 501 L E+ + IKE+LRLHPP+ M+ R D + GK IP G R Sbjct: 358 LGELKFMENVIKESLRLHPPVPMIGRWFAEDVEI---RGKH--IPAGTNFTMGIFVLLRD 412 Query: 500 PHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRN 321 P F++PD + P+RF A + ++YI F G C+G+ FA L++K+ + LLR+ Sbjct: 413 PEYFESPDEFRPERFDADVPQ---IHPYAYIPFSAGPRNCIGQKFAMLEMKSTVSKLLRH 469 Query: 320 FEFELVSPFPENDWNAMVVGIKG 252 FE + P P + N ++ G Sbjct: 470 FELLPLGPEPRHSMNIVLRSANG 492
>CP26A_MOUSE (O55127) Cytochrome P450 26A1 (EC 1.14.-.-) (Retinoic| acid-metabolizing cytochrome) (P450RAI) (Retinoic acid 4-hydroxylase) Length = 497 Score = 73.6 bits (179), Expect = 6e-13 Identities = 46/137 (33%), Positives = 73/137 (53%) Frame = -2 Query: 701 DKIDHDILAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATS 522 +K+D + L ++ + IKE LRL+PP+ R ++ T E + IPKG V S Sbjct: 343 NKLDMETLEQLKYIGCVIKETLRLNPPVPGGFR-----VALKTFELNGYQIPKGWNVIYS 397 Query: 521 PAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAI 342 + + IF N + ++PDRF ED A FS+I FGGG C+G+ FA + +K Sbjct: 398 ICDTHDVADIFTNKEEFNPDRFIVPHPED--ASRFSFIPFGGGLRSCVGKEFAKILLKIF 455 Query: 341 WTHLLRNFEFELVSPFP 291 L R+ +++L++ P Sbjct: 456 TVELARHCDWQLLNGPP 472
>C6A13_DROME (Q9V4U9) Probable cytochrome P450 6a13 (EC 1.14.-.-) (CYPVIA13)| Length = 493 Score = 73.2 bits (178), Expect = 8e-13 Identities = 45/138 (32%), Positives = 70/138 (50%), Gaps = 5/138 (3%) Frame = -2 Query: 710 RHGDKIDHDILAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTRE-----GKEFDIP 546 R+ K+ +D + EM L + + E LR +P L LLR+S ++ + G + IP Sbjct: 331 RNNQKLTYDSVQEMPYLDQVVAETLRKYPILPHLLRRSTKEYQIPNSNLILEPGSKIIIP 390 Query: 545 KGHIVATSPAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPF 366 I + P ++ +P+ +DP RF EE K F+Y+ FG G C+GE F Sbjct: 391 VHSI--------HHDPELYPDPEKFDPSRFEP--EEIKARHPFAYLPFGEGPRNCIGERF 440 Query: 365 AYLQIKAIWTHLLRNFEF 312 LQ+K +LLR+F+F Sbjct: 441 GKLQVKVGLVYLLRDFKF 458
>CP4AA_MOUSE (O88833) Cytochrome P450 4A10 (EC 1.14.15.3) (CYPIVA10) (Lauric| acid omega-hydroxylase) (P450-LA-omega 1) (P452) Length = 509 Score = 72.8 bits (177), Expect = 1e-12 Identities = 46/130 (35%), Positives = 69/130 (53%) Frame = -2 Query: 704 GDKIDHDILAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVAT 525 G I D L ++ CIKEALRL+PP+ ++R+ + SVT +G+ +PKG V Sbjct: 357 GSSITWDHLDQIPYTTMCIKEALRLYPPVPGIVRELST--SVTFPDGR--SLPKGVQVTL 412 Query: 524 SPAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKA 345 S + P ++ NP+ +DP RFA D + S++ F GG C+G+ FA ++K Sbjct: 413 SIYGLHHNPKVWPNPEVFDPSRFA----PDSPRHSHSFLPFSGGARNCIGKQFAMSELKV 468 Query: 344 IWTHLLRNFE 315 I L FE Sbjct: 469 IVALTLLRFE 478
>CP6B5_PAPGL (Q95036) Cytochrome P450 6B5 (EC 1.14.14.1) (CYPVIB5) (CYP6B5V1)| (Fragment) Length = 476 Score = 72.4 bits (176), Expect = 1e-12 Identities = 44/134 (32%), Positives = 67/134 (50%) Frame = -2 Query: 710 RHGDKIDHDILAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIV 531 RH +I +D L+EM L + E LR +P +LLR + +D++V G + KG V Sbjct: 339 RHNGEITYDTLSEMTYLTQVFHETLRKYPVADILLRNAKADYAV---PGTNVTLKKGQTV 395 Query: 530 ATSPAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQI 351 S + P + +P+ +DP+RF+ E + +YI FG G+ CLG F Q+ Sbjct: 396 VVSGFGIHYDPKYYPDPEKFDPERFSP--ENVRNRHPCAYIPFGAGQRKCLGMRFGQWQV 453 Query: 350 KAIWTHLLRNFEFE 309 + LL F FE Sbjct: 454 QVCIIKLLSKFRFE 467
>CP6G2_DROME (Q9V675) Probable cytochrome P450 6g2 (EC 1.14.-.-) (CYPVIG2)| Length = 519 Score = 72.4 bits (176), Expect = 1e-12 Identities = 54/170 (31%), Positives = 84/170 (49%), Gaps = 6/170 (3%) Frame = -2 Query: 704 GDKIDHDILAEMDVLYRCIKEALRLHPPLIMLLRQSHS--DFSVTTREGKEFDIPKGHIV 531 G ++ ++ ++ + + E LR++PPL L R+ S D+S+ K+F +PKG V Sbjct: 354 GGQVTLKMIESLEFMQMILLEVLRMYPPLPFLDRECTSGRDYSLAPFH-KKFVVPKGMPV 412 Query: 530 ATSPAFANRL-PHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQ 354 P +A + P F P + P+RF+ E K+ ++Y+ FG G HGC+GE F YLQ Sbjct: 413 YI-PCYALHMDPQYFPQPRKFLPERFSP--ENRKLHTPYTYMPFGLGPHGCIGERFGYLQ 469 Query: 353 IKAIWTHLLRNFEFELVSPFPEN---DWNAMVVGIKGEVMVNYKRRKLVV 213 K +LLRN P D A++ KG + + R L V Sbjct: 470 AKVGLVNLLRNHMITTSERTPHRMQLDPKAIITQAKGGIHLRLVRDALGV 519
>CP4AA_RAT (P08516) Cytochrome P450 4A10 (EC 1.14.15.3) (CYPIVA10) (Lauric| acid omega-hydroxylase) (P450-LA-omega 1) (P452) Length = 509 Score = 72.4 bits (176), Expect = 1e-12 Identities = 46/130 (35%), Positives = 69/130 (53%) Frame = -2 Query: 704 GDKIDHDILAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVAT 525 G I D L ++ CIKEALRL+PP+ ++R+ + SVT +G+ +PKG V Sbjct: 357 GSSITWDHLDQIPYTTMCIKEALRLYPPVPGIVRELST--SVTFPDGR--SLPKGIQVTL 412 Query: 524 SPAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKA 345 S + P ++ NP+ +DP RFA D + S++ F GG C+G+ FA ++K Sbjct: 413 SIYGLHHNPKVWPNPEVFDPSRFA----PDSPRHSHSFLPFSGGARNCIGKQFAMSEMKV 468 Query: 344 IWTHLLRNFE 315 I L FE Sbjct: 469 IVALTLLRFE 478
>CP6B4_PAPGL (Q27902) Cytochrome P450 6B4 (EC 1.14.14.1) (CYPVIB4)| (CYP6B4V1/CYP6B4V2) Length = 500 Score = 72.4 bits (176), Expect = 1e-12 Identities = 44/134 (32%), Positives = 67/134 (50%) Frame = -2 Query: 710 RHGDKIDHDILAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIV 531 RH +I +D L+EM L + E LR +P +LLR + +D++V G + KG V Sbjct: 339 RHNGEITYDTLSEMTYLTQVFHETLRKYPVADILLRNAKADYAV---PGTNVTLKKGQTV 395 Query: 530 ATSPAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQI 351 S + P + +P+ +DP+RF+ E + +YI FG G+ CLG F Q+ Sbjct: 396 VVSGFGIHYDPKYYPDPEKFDPERFSP--ENVRNRHPCAYIPFGAGQRKCLGMRFGQWQV 453 Query: 350 KAIWTHLLRNFEFE 309 + LL F FE Sbjct: 454 QVCIIKLLSKFRFE 467
>C4AA1_DROME (Q9V7G5) Probable cytochrome P450 4aa1 (EC 1.14.-.-) (CYPIVAA1)| Length = 514 Score = 72.0 bits (175), Expect = 2e-12 Identities = 38/122 (31%), Positives = 68/122 (55%) Frame = -2 Query: 680 LAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFANRL 501 L EM + CIKEALRL+P + ++ R+ + + + +P G V P +RL Sbjct: 362 LHEMRYMEMCIKEALRLYPSVPLIARKLGEEVRLA-----KHTLPAGSNVFICPYATHRL 416 Query: 500 PHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRN 321 HI+ +P+ + P+RF+ E++ ++++ F G C+G FA ++IK I + LLR+ Sbjct: 417 AHIYPDPEKFQPERFSPENSENR--HPYAFLPFSAGPRYCIGNRFAIMEIKTIVSRLLRS 474 Query: 320 FE 315 ++ Sbjct: 475 YQ 476
>CP9F2_DROME (Q9VG82) Probable cytochrome P450 9f2 (EC 1.14.-.-) (CYPIXF2)| Length = 516 Score = 71.6 bits (174), Expect = 2e-12 Identities = 38/131 (29%), Positives = 71/131 (54%) Frame = -2 Query: 704 GDKIDHDILAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVAT 525 G ++ ++ + M L + + E LR P I + R+ + D + +G++ ++ KG ++ Sbjct: 356 GKELTYEAIMGMKYLDQVVNEVLRKWPAAIAVDRECNKDITFDV-DGQKVEVKKGDVIWL 414 Query: 524 SPAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKA 345 +R P F+NP +DP+RF+ +E F+Y FG G+ C+G FA L+ KA Sbjct: 415 PTCGFHRDPKYFENPMKFDPERFSDENKES--IQPFTYFPFGLGQRNCIGSRFALLEAKA 472 Query: 344 IWTHLLRNFEF 312 + +LL+++ F Sbjct: 473 VIYYLLKDYRF 483
>CP4F6_RAT (P51871) Cytochrome P450 4F6 (EC 1.14.14.1) (CYPIVF6)| Length = 537 Score = 71.6 bits (174), Expect = 2e-12 Identities = 45/130 (34%), Positives = 72/130 (55%), Gaps = 1/130 (0%) Frame = -2 Query: 710 RHGDKIDHDILAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIV 531 R ++I+ D LA++ L CIKE+LRLHPP++++ R D + +G+ IPKG+I Sbjct: 365 REPEEIEWDDLAQLPFLTMCIKESLRLHPPVLLISRCCSQD--IVLPDGRV--IPKGNIC 420 Query: 530 ATSPAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQI 351 S + P ++ +P+ Y+P RF E + ++I F G C+G+ FA +I Sbjct: 421 VISIFGVHHNPSVWPDPEVYNPFRF--DPENPQKRSPLAFIPFSAGPRNCIGQTFAMSEI 478 Query: 350 K-AIWTHLLR 324 K A+ LLR Sbjct: 479 KVALALTLLR 488
>CP6K1_BLAGE (Q964R0) Cytochrome P450 6k1 (EC 1.14.-.-) (CYPVIK1)| Length = 524 Score = 71.6 bits (174), Expect = 2e-12 Identities = 40/119 (33%), Positives = 61/119 (51%) Frame = -2 Query: 671 MDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFANRLPHI 492 M L+ + E LR +PPL +L R D+ V G + I + V + +R P Sbjct: 373 MPYLHMVVSETLRKYPPLPLLDRVCLQDYKVP---GTDLIIERDTPVFIALLGLHRDPQY 429 Query: 491 FKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFE 315 + NP+ YDP+RF+ E + A++Y+ FG G H C+G F Y+ +K H+L FE Sbjct: 430 YPNPERYDPERFS--EENKRQRKAYTYLPFGEGPHNCIGLRFGYMAVKTALVHMLAEFE 486
>CP4AE_MOUSE (O35728) Cytochrome P450 4A14 precursor (EC 1.14.15.3) (CYPIVA14)| (Lauric acid omega-hydroxylase 3) (P450-LA-omega 3) Length = 507 Score = 71.2 bits (173), Expect = 3e-12 Identities = 46/130 (35%), Positives = 64/130 (49%) Frame = -2 Query: 704 GDKIDHDILAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVAT 525 G + D L +M CIKEALRL+PP+I + R+ S VT +G+ IPKG Sbjct: 355 GTSVTWDHLGQMPYTTMCIKEALRLYPPVISVSRELSS--PVTFPDGR--SIPKGITATI 410 Query: 524 SPAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKA 345 S + P + NP +DP RFA D + +Y+ F GG C+G+ FA ++K Sbjct: 411 SIYGLHHNPRFWPNPKVFDPSRFA----PDSSHHSHAYLPFSGGSRNCIGKQFAMNELKV 466 Query: 344 IWTHLLRNFE 315 L FE Sbjct: 467 AVALTLLRFE 476
>C6A14_DROME (Q9V4U7) Probable cytochrome P450 6a14 (EC 1.14.-.-) (CYPVIA14)| Length = 509 Score = 70.9 bits (172), Expect = 4e-12 Identities = 41/133 (30%), Positives = 67/133 (50%) Frame = -2 Query: 704 GDKIDHDILAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVAT 525 G ++++D+LA+M L + + E LR HP L L+R++ D+ + + + KG + Sbjct: 352 GGELNYDVLAQMTYLDQVLSETLRKHPLLPHLIRETTKDYQI---PNSDIVLDKGILALI 408 Query: 524 SPAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKA 345 + P I+ P+ +DP RF EE K +Y+ FG G C+G F +Q K Sbjct: 409 PVHNIHHDPEIYPEPEKFDPSRF--DPEEVKNRHPMAYLPFGDGPRNCIGLRFGKIQAKI 466 Query: 344 IWTHLLRNFEFEL 306 LLR F+F + Sbjct: 467 GLVSLLRRFKFSV 479
>CP4G1_DROME (Q9V3S0) Cytochrome P450 4g1 (EC 1.14.-.-) (CYPIVG1)| Length = 556 Score = 70.5 bits (171), Expect = 5e-12 Identities = 38/119 (31%), Positives = 63/119 (52%) Frame = -2 Query: 674 EMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFANRLPH 495 EM L R I E LRL+PP+ ++ R+ D + + + +PKG V +R P Sbjct: 405 EMKYLERVILETLRLYPPVPLIARRLDYDLKLASGP---YTVPKGTTVIVLQYCVHRRPD 461 Query: 494 IFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNF 318 I+ NP +DPD F R ++ +S+I F G C+G +A L++K + + ++RN+ Sbjct: 462 IYPNPTKFDPDNFLPERMANR--HYYSFIPFSAGPRSCVGRKYAMLKLKVLLSTIVRNY 518
>CP6B6_HELAM (Q95031) Cytochrome P450 6B6 (EC 1.14.14.1) (CYPVIB6)| Length = 504 Score = 70.1 bits (170), Expect = 6e-12 Identities = 53/167 (31%), Positives = 77/167 (46%), Gaps = 6/167 (3%) Frame = -2 Query: 698 KIDHDILAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSP 519 K+ +D + EM + + E LR++ + L R++ D+ + G + I K IV SP Sbjct: 345 KVTYDTVKEMKYMNKAFDETLRMYSIVEPLQRKATRDYKIP---GTDVVIEKDTIVLISP 401 Query: 518 AFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIW 339 + P + NP ++PDRF A EE +Y+ FG G+ C+G F LQ Sbjct: 402 RGIHYDPKYYDNPKQFNPDRFDA--EEVGKRHPCAYLPFGLGQRNCIGMRFGRLQSLLCI 459 Query: 338 THLLRNFEFELVSPFPENDWNAMV------VGIKGEVMVNYKRRKLV 216 T +L F E P D N V +G KG + VN RKLV Sbjct: 460 TKILSKFRIE---PSKNTDRNLQVEPHRGLIGPKGGIRVNVVPRKLV 503
>CP4FE_MOUSE (Q9EP75) Cytochrome P450 4F14 (EC 1.14.13.30) (Leukotriene-B4| omega-hydroxylase) (Leukotriene-B4 20-monooxygenase) (Cytochrome P450-LTB-omega) (Cyp4f-14) Length = 524 Score = 69.3 bits (168), Expect = 1e-11 Identities = 46/130 (35%), Positives = 71/130 (54%), Gaps = 1/130 (0%) Frame = -2 Query: 710 RHGDKIDHDILAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIV 531 R ++I+ D LA++ L CIKE+LRLHPP+ ++ R D + +G+ IPKG I Sbjct: 365 REPEEIEWDDLAQLPFLTMCIKESLRLHPPVTVISRCCTQD--ILLPDGR--TIPKGIIC 420 Query: 530 ATSPAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQI 351 S + P ++ +P+ YDP RF E K + ++I F G C+G+ FA ++ Sbjct: 421 LISIFGIHHNPSVWPDPEVYDPFRF--DPENIKDSSPLAFIPFSAGPRNCIGQTFAMSEM 478 Query: 350 K-AIWTHLLR 324 K A+ LLR Sbjct: 479 KVALALTLLR 488
>CP4FB_HUMAN (Q9HBI6) Cytochrome P450 4F11 (EC 1.14.14.1) (CYPIVF11)| Length = 524 Score = 69.3 bits (168), Expect = 1e-11 Identities = 42/127 (33%), Positives = 69/127 (54%) Frame = -2 Query: 698 KIDHDILAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSP 519 +I+ D LA++ L CIKE+LRLHPP+ ++ R DF + +G+ IPKG + + Sbjct: 369 EIEWDDLAQLPFLTMCIKESLRLHPPVPVISRCCTQDFVLP--DGRV--IPKGIVCLINI 424 Query: 518 AFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIW 339 + P ++ +P+ YDP RF +E K ++I F G C+G+ FA ++K + Sbjct: 425 IGIHYNPTVWPDPEVYDPFRF--NQENIKERSPLAFIPFSAGPRNCIGQAFAMAEMKVVL 482 Query: 338 THLLRNF 318 L +F Sbjct: 483 ALTLLHF 489
>CP4F4_RAT (P51869) Cytochrome P450 4F4 (EC 1.14.14.1) (CYPIVF4)| Length = 522 Score = 68.9 bits (167), Expect = 1e-11 Identities = 44/130 (33%), Positives = 71/130 (54%), Gaps = 1/130 (0%) Frame = -2 Query: 710 RHGDKIDHDILAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIV 531 R +I+ D LA++ L CIKE+LRLHPP+ ++ R+ D + +G+ IPKG I Sbjct: 365 RESTEIEWDDLAQLPFLTMCIKESLRLHPPVTVISRRCTQD--IVLPDGRV--IPKGVIC 420 Query: 530 ATSPAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQI 351 + + P ++ +P+ YDP RF +D+ ++I F G C+G+ FA ++ Sbjct: 421 IINIFATHHNPTVWPDPEVYDPFRFDPENIKDR--SPLAFIPFSAGPRNCIGQTFAMNEM 478 Query: 350 K-AIWTHLLR 324 K A+ LLR Sbjct: 479 KVALALTLLR 488
>CP4FC_HUMAN (Q9HCS2) Cytochrome P450 4F12 (EC 1.14.14.1) (CYPIVF12)| Length = 524 Score = 68.6 bits (166), Expect = 2e-11 Identities = 42/133 (31%), Positives = 66/133 (49%) Frame = -2 Query: 710 RHGDKIDHDILAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIV 531 R +I+ D LA++ L C+KE+LRLHPP + R D + +G+ IPKG Sbjct: 365 RDPKEIEWDDLAQLPFLTMCVKESLRLHPPAPFISRCCTQD--IVLPDGRV--IPKGITC 420 Query: 530 ATSPAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQI 351 + P ++ +P+ YDP RF E K ++I F G C+G+ FA ++ Sbjct: 421 LIDIIGVHHNPTVWPDPEVYDPFRFDP--ENSKGRSPLAFIPFSAGPRNCIGQAFAMAEM 478 Query: 350 KAIWTHLLRNFEF 312 K + +L +F F Sbjct: 479 KVVLALMLLHFRF 491
>CP6B7_HELAM (O61387) Cytochrome P450 6B7 (EC 1.14.14.1) (CYPVIB7)| Length = 504 Score = 68.6 bits (166), Expect = 2e-11 Identities = 52/167 (31%), Positives = 77/167 (46%), Gaps = 6/167 (3%) Frame = -2 Query: 698 KIDHDILAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSP 519 K+ +D + EM L + E LR++ + L R++ D+ + G + I K +V SP Sbjct: 345 KVTYDTVKEMKYLNKVFDETLRMYSIVEPLQRKATRDYQIP---GTDVVIEKDTMVLISP 401 Query: 518 AFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIW 339 + P + NP ++PDRF A EE +Y+ FG G+ C+G F LQ Sbjct: 402 RGIHYDPKYYDNPKQFNPDRFDA--EEVGKRHPCAYLPFGLGQRNCIGMRFGRLQSLLCI 459 Query: 338 THLLRNFEFELVSPFPENDWNAMV------VGIKGEVMVNYKRRKLV 216 T +L F E P D N V +G KG + VN RK+V Sbjct: 460 TKILSKFRIE---PSKNTDRNLQVEPRRVTIGPKGGIRVNIVPRKIV 503
>THAS_PIG (P47787) Thromboxane-A synthase (EC 5.3.99.5) (TXA synthase) (TXS)| Length = 534 Score = 68.2 bits (165), Expect = 2e-11 Identities = 36/114 (31%), Positives = 58/114 (50%) Frame = -2 Query: 650 IKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFANRLPHIFKNPDSY 471 + E LR++PP R++ D V + IP G ++ + + P + +P+++ Sbjct: 398 LSETLRMYPPAFRFTREAARDCEVLGQR-----IPAGTVLEVAVGALHHDPKHWPHPETF 452 Query: 470 DPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFE 309 DP+RF A E ++ F+Y+ FG G CLG L+IK H+LR F FE Sbjct: 453 DPERFTA--EAQRLQQPFTYLPFGAGPRSCLGVQLGLLEIKLTLLHILRKFRFE 504
>CP4F2_HUMAN (P78329) Cytochrome P450 4F2 (EC 1.14.13.30) (CYPIVF2)| (Leukotriene-B(4) omega-hydroxylase) (Leukotriene-B(4) 20-monooxygenase) (Cytochrome P450-LTB-omega) Length = 520 Score = 68.2 bits (165), Expect = 2e-11 Identities = 43/131 (32%), Positives = 66/131 (50%) Frame = -2 Query: 710 RHGDKIDHDILAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIV 531 R +I+ D LA + L C+KE+LRLHPP+ ++ R H + +G+ IPKG I Sbjct: 365 REPKEIEWDDLAHLPFLTMCMKESLRLHPPVPVISR--HVTQDIVLPDGRV--IPKGIIC 420 Query: 530 ATSPAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQI 351 S + P ++ +P+ YDP RF E K ++I F G C+G+ FA ++ Sbjct: 421 LISVFGTHHNPAVWPDPEVYDPFRF--DPENIKERSPLAFIPFSAGPRNCIGQTFAMAEM 478 Query: 350 KAIWTHLLRNF 318 K + L F Sbjct: 479 KVVLALTLLRF 489
>CP26A_CHICK (Q9PUB4) Cytochrome P450 26A1 (EC 1.14.-.-) (Retinoic acid| degrading enzyme CYP26) Length = 492 Score = 67.8 bits (164), Expect = 3e-11 Identities = 45/161 (27%), Positives = 80/161 (49%), Gaps = 10/161 (6%) Frame = -2 Query: 698 KIDHDILAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSP 519 +++ + L ++ IKE LRL PP+ R ++ T E + IPKG V S Sbjct: 339 QLNMEFLEQLKYTGCVIKETLRLSPPVPGGFR-----IALKTLELNGYQIPKGWNVIYSI 393 Query: 518 AFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIW 339 + + +F + D ++PDRF + ED + FS+I FGGG C+G+ FA + +K Sbjct: 394 CDTHDVADLFTDKDEFNPDRFMSPSPED--SSRFSFIPFGGGLRSCVGKEFAKVLLKIFT 451 Query: 338 THLLRNFEFELVS----------PFPENDWNAMVVGIKGEV 246 L R+ +++L++ +P ++ A +G G++ Sbjct: 452 VELARSCDWQLLNGPPTMKTGPIVYPVDNLPAKFIGFSGQI 492
>CP51_UNCNE (O14442) Cytochrome P450 51 (EC 1.14.13.70) (CYPLI) (P450-LIA1)| (Sterol 14-alpha demethylase) (Eburicol 14-alpha-demethylase) (P450-14DM) Length = 524 Score = 67.8 bits (164), Expect = 3e-11 Identities = 44/145 (30%), Positives = 73/145 (50%), Gaps = 17/145 (11%) Frame = -2 Query: 695 IDHDILAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPA 516 + ++ L+++ + +KE LRLH P+ ++R+ + V G ++ IP H++ +SP Sbjct: 351 LQYEDLSKLQLHQNVLKEVLRLHAPIHSIMRKVKNPMIVP---GTKYVIPTSHVLISSPG 407 Query: 515 FANRLPHIFKNPDSYDPDRFAAGREE----DKV------------AGAFS-YISFGGGRH 387 ++ F +P +DP R+ G + D V GA S Y+ FG GRH Sbjct: 408 CTSQDATFFPDPLKWDPHRWDIGSGKVLGNDAVDEKYDYGYGLTSTGASSPYLPFGAGRH 467 Query: 386 GCLGEPFAYLQIKAIWTHLLRNFEF 312 C+GE FA LQ+ I ++R F F Sbjct: 468 RCIGEQFATLQLVTIMATMVRFFRF 492
>CP4AC_MOUSE (Q91WL5) Cytochrome P450 4A12 (EC 1.14.14.1) (CYPIVA12)| Length = 508 Score = 67.0 bits (162), Expect = 5e-11 Identities = 44/130 (33%), Positives = 66/130 (50%) Frame = -2 Query: 704 GDKIDHDILAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVAT 525 G I + L +M CIKEALR++PP+ + R+ S VT +G+ +PKG V Sbjct: 356 GTSITWNDLDKMPYTTMCIKEALRIYPPVPSVSRELSSP--VTFPDGRS--LPKGIHVML 411 Query: 524 SPAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKA 345 S + P ++ NP+ +DP RFA G + S++ F GG C+G+ FA ++K Sbjct: 412 SFYGLHHNPTVWPNPEVFDPSRFAPGSSRH----SHSFLPFSGGARNCIGKQFAMNELKV 467 Query: 344 IWTHLLRNFE 315 L FE Sbjct: 468 AVALTLLRFE 477
>CP4F1_RAT (P33274) Cytochrome P450 4F1 (EC 1.14.14.1) (CYPIVF1) (P450-A3)| Length = 524 Score = 67.0 bits (162), Expect = 5e-11 Identities = 45/130 (34%), Positives = 71/130 (54%), Gaps = 1/130 (0%) Frame = -2 Query: 710 RHGDKIDHDILAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIV 531 R ++I+ D LA++ L CIKE+LRLHPP+ ++ R D + +G+ IPKG I Sbjct: 365 RDPEEIEWDDLAQLPFLTMCIKESLRLHPPVTVISRCCTQD--ILLPDGR--TIPKGIIC 420 Query: 530 ATSPAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQI 351 S + P ++ +P+ Y+P RF E K + ++I F G C+G+ FA ++ Sbjct: 421 LISIFGIHHNPSVWPDPEVYNPFRF--DPENIKDSSPLAFIPFSAGPRNCIGQTFAMSEM 478 Query: 350 K-AIWTHLLR 324 K A+ LLR Sbjct: 479 KVALALTLLR 488
>CP26C_HUMAN (Q6V0L0) Cytochrome P450 26C1 (EC 1.14.-.-)| Length = 522 Score = 67.0 bits (162), Expect = 5e-11 Identities = 43/123 (34%), Positives = 66/123 (53%), Gaps = 3/123 (2%) Frame = -2 Query: 650 IKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFANRLPHIFKNP-DS 474 +KE LRL PP+ R + + T E + IPKG V S + ++++P + Sbjct: 373 VKEVLRLLPPVSGGYRTA-----LRTFELDGYQIPKGWSVMYSIRDTHETAAVYRSPPEG 427 Query: 473 YDPDRFAAGREEDKVAGA-FSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFELVSP 297 +DP+RF A RE+ + A + F YI FGGG CLG+ A ++ + L+R +EL +P Sbjct: 428 FDPERFGAAREDSRGASSRFHYIPFGGGARSCLGQELAQAVLQLLAVELVRTARWELATP 487 Query: 296 -FP 291 FP Sbjct: 488 AFP 490
>CP4A4_RABIT (P10611) Cytochrome P450 4A4 precursor (EC 1.14.14.1) (CYPIVA4)| (Prostaglandin omega-hydroxylase) (P450-P-2) Length = 510 Score = 67.0 bits (162), Expect = 5e-11 Identities = 44/130 (33%), Positives = 67/130 (51%) Frame = -2 Query: 704 GDKIDHDILAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVAT 525 G I + L +M CIKEALRL+PP+ + RQ VT +G+ +PKG I+ Sbjct: 358 GASITWEHLDQMPYTTMCIKEALRLYPPVPSVTRQLSK--PVTFPDGR--SLPKGVILFL 413 Query: 524 SPAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKA 345 S + P +++NP+ +DP RFA D + +++ F GG C+G+ FA ++K Sbjct: 414 SIYGLHYNPKVWQNPEVFDPFRFA----PDSAYHSHAFLPFSGGARNCIGKQFAMRELKV 469 Query: 344 IWTHLLRNFE 315 L FE Sbjct: 470 AVALTLVRFE 479
>CP6U1_DROME (Q9V979) Probable cytochrome P450 6u1 (EC 1.14.-.-) (CYPVIU1)| Length = 488 Score = 67.0 bits (162), Expect = 5e-11 Identities = 43/132 (32%), Positives = 63/132 (47%) Frame = -2 Query: 707 HGDKIDHDILAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVA 528 HG ++ + L E+ + + E LRLH P LLR++ +F V G F I KG+ V Sbjct: 327 HGGQVTPECLRELRYTKQVLNETLRLHTPHPFLLRRATKEFEV---PGSVFVIAKGNNVL 383 Query: 527 TSPAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIK 348 A + P I++NP + P+RF + A AF + FG G GC+ FA Q+ Sbjct: 384 IPTAAIHMDPGIYENPQRFYPERFEEQARRSRPAAAF--LPFGDGLRGCIAARFAEQQLL 441 Query: 347 AIWTHLLRNFEF 312 LLR + Sbjct: 442 VGLVALLRQHRY 453
>CP11A_DASAM (Q92045) Cytochrome P450 11A1, mitochondrial precursor (EC| 1.14.15.6) (CYPXIA1) (P450(SCC)) (Cholesterol side-chain cleavage enzyme) (Cholesterol desmolase) (Fragment) Length = 514 Score = 67.0 bits (162), Expect = 5e-11 Identities = 39/125 (31%), Positives = 63/125 (50%) Frame = -2 Query: 683 ILAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFANR 504 +L + +L +KE LRL+P I + R + D + + + IP G +V R Sbjct: 371 MLKSVPLLKCVVKETLRLYPVAISIQRYLNEDTVL-----QNYHIPAGTLVQLGLYAMGR 425 Query: 503 LPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLR 324 P IFKNP+ Y+P+R+ G + F ++ FG G C+G A Q+ + H+L+ Sbjct: 426 NPKIFKNPEQYNPERWLKGEDTH-----FRHLGFGFGPRQCIGRRIAETQMVLLMIHMLQ 480 Query: 323 NFEFE 309 NF+ E Sbjct: 481 NFKIE 485
>CP26B_HUMAN (Q9NR63) Cytochrome P450 26B1 (EC 1.14.-.-) (P450 26A2) (P450| retinoic acid-inactivating 2) (P450RAI-2) (Retinoic-acid metabolizing cytochrome) Length = 512 Score = 66.6 bits (161), Expect = 7e-11 Identities = 46/129 (35%), Positives = 62/129 (48%) Frame = -2 Query: 686 DILAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFAN 507 D L+ + L IKE +RL P+ R F + F IPKG V S + Sbjct: 346 DTLSGLRYLDCVIKEVMRLFTPISGGYRTVLQTFELDG-----FQIPKGWSVMYSIRDTH 400 Query: 506 RLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLL 327 +FK+ + +DPDRF+ R EDK G F Y+ FGGG CLG+ A L +K + L Sbjct: 401 DTAPVFKDVNVFDPDRFSQARSEDK-DGRFHYLPFGGGVRTCLGKHLAKLFLKVLAVELA 459 Query: 326 RNFEFELVS 300 FEL + Sbjct: 460 STSRFELAT 468
>CP4A5_RABIT (P14579) Cytochrome P450 4A5 precursor (EC 1.14.15.3) (CYPIVA5)| (Lauric acid omega-hydroxylase) Length = 511 Score = 66.6 bits (161), Expect = 7e-11 Identities = 42/130 (32%), Positives = 65/130 (50%) Frame = -2 Query: 704 GDKIDHDILAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVAT 525 G I + L +M CIKEA+RL+PP+ + R S VT +G+ +PKG V Sbjct: 359 GASITWEHLDQMPYTTMCIKEAMRLYPPVPAISRDLSSP--VTFPDGRS--LPKGFTVTL 414 Query: 524 SPAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKA 345 S + P+++ NP+ +DP RF G + +++ F GG C+G+ FA ++K Sbjct: 415 SIYGLHHNPNVWPNPEVFDPGRFTPG----SARHSHAFLPFSGGARNCIGKQFAMNELKV 470 Query: 344 IWTHLLRNFE 315 L FE Sbjct: 471 AVALTLVRFE 480
>CP4B1_RAT (P15129) Cytochrome P450 4B1 (EC 1.14.14.1) (CYPIVB1) (P450-isozyme| 5) (P450 L-2) Length = 510 Score = 66.2 bits (160), Expect = 9e-11 Identities = 43/136 (31%), Positives = 69/136 (50%), Gaps = 4/136 (2%) Frame = -2 Query: 701 DKIDHDILAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATS 522 D D LA+M L C+KE RL+PP+ + RQ + VT +G+ +P G +++ Sbjct: 352 DSFQWDDLAKMTYLTMCMKECFRLYPPVPQVYRQLNK--PVTFVDGR--SLPAGSLISLH 407 Query: 521 PAFANRLPHIFKNPDSYDPDRF----AAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQ 354 +R ++ +P+ +DP RF AAGR F+++ F G C+G+ FA + Sbjct: 408 IYALHRNSTVWPDPEVFDPLRFSPENAAGRH------PFAFMPFSAGPRNCIGQQFAMNE 461 Query: 353 IKAIWTHLLRNFEFEL 306 +K + L FEF L Sbjct: 462 MKVVTALCLLRFEFSL 477
>CP4A6_RABIT (P14580) Cytochrome P450 4A6 precursor (EC 1.14.15.3) (CYPIVA6)| (Lauric acid omega-hydroxylase) (P450-KA-1) Length = 510 Score = 66.2 bits (160), Expect = 9e-11 Identities = 53/162 (32%), Positives = 79/162 (48%) Frame = -2 Query: 704 GDKIDHDILAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVAT 525 G I + L +M CIKEALRL+PP+ + RQ S VT +G+ +PKG IV Sbjct: 358 GASITWEHLDQMPYTTMCIKEALRLYPPVPGVGRQLSSP--VTFPDGRS--LPKGVIVTL 413 Query: 524 SPAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKA 345 S + P ++ NP+ +DP FA G + +++ F GG C+G+ FA ++K Sbjct: 414 SIYALHHNPKVWPNPEVFDPFPFAPG----SARHSHAFLPFSGGPRNCIGKQFAMNELKV 469 Query: 344 IWTHLLRNFEFELVSPFPENDWNAMVVGIKGEVMVNYKRRKL 219 L FE L P D +V +K ++ + RKL Sbjct: 470 AVALTLVRFEL-LPDPKRVPDQKPRLV-LKSSNGIHLRLRKL 509
>CP4AB_HUMAN (Q02928) Cytochrome P450 4A11 precursor (EC 1.14.15.3) (CYPIVA11)| (Fatty acid omega-hydroxylase) (P-450 HK omega) (Lauric acid omega-hydroxylase) (CYP4AII) (P450-HL-omega) Length = 519 Score = 66.2 bits (160), Expect = 9e-11 Identities = 43/130 (33%), Positives = 68/130 (52%) Frame = -2 Query: 704 GDKIDHDILAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVAT 525 G I + L +M CIKEALRL+PP+ + R+ + VT +G+ +PKG +V Sbjct: 358 GASITWNHLDQMPYTTMCIKEALRLYPPVPGIGRELSTP--VTFPDGRS--LPKGIMVLL 413 Query: 524 SPAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKA 345 S + P ++ NP+ +DP RFA G + + +++ F GG C+G+ FA ++K Sbjct: 414 SIYGLHHNPKVWPNPEVFDPFRFAPGSAQH----SHAFLPFSGGSRNCIGKQFAMNELKV 469 Query: 344 IWTHLLRNFE 315 L FE Sbjct: 470 ATALTLLRFE 479
>CP3AF_CAVPO (Q64406) Cytochrome P450 3A15 (EC 1.14.14.1) (CYPIIIA15)| Length = 503 Score = 66.2 bits (160), Expect = 9e-11 Identities = 42/127 (33%), Positives = 65/127 (51%), Gaps = 1/127 (0%) Frame = -2 Query: 689 HDILAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFA 510 +D++ EM+ L + E LRL+P + R S DF + G F PKG +V P+FA Sbjct: 347 YDVMMEMEYLDMVVNETLRLYPVANRIERMSKKDFEIN---GMSF--PKGTLVMI-PSFA 400 Query: 509 -NRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTH 333 +R + PD + P+RF+ +E+ + Y+ FG G C+G A + +K Sbjct: 401 LHRDSKYWPEPDEFRPERFSKKNKEN--IDPYIYMPFGNGPRNCIGRRMALMNLKLALIR 458 Query: 332 LLRNFEF 312 LL+NF F Sbjct: 459 LLQNFSF 465
>CP4D8_DROME (Q9VS79) Cytochrome P450 4d8 (EC 1.14.-.-) (CYPIVD8)| Length = 463 Score = 65.9 bits (159), Expect = 1e-10 Identities = 37/122 (30%), Positives = 60/122 (49%) Frame = -2 Query: 680 LAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFANRL 501 L E+ + IKE+LR++PP+ ++ R+ +DF T + IP G + +R Sbjct: 314 LGELKYMECVIKESLRMYPPVPIVGRKLQTDFKYTHSVHGDGVIPAGSEIIIGIFGVHRQ 373 Query: 500 PHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRN 321 P F NPD + P+R E F I F G C+G+ FA L++K + ++R Sbjct: 374 PETFPNPDEFIPER----HENGSRVAPFKMIPFSAGPRNCIGQKFAQLEMKMMLAKIVRE 429 Query: 320 FE 315 +E Sbjct: 430 YE 431
>CP4F3_HUMAN (Q08477) Cytochrome P450 4F3 (EC 1.14.13.30) (CYPIVF3)| (Leukotriene-B(4) omega-hydroxylase) (Leukotriene-B(4) 20-monooxygenase) (Cytochrome P450-LTB-omega) Length = 520 Score = 65.9 bits (159), Expect = 1e-10 Identities = 41/123 (33%), Positives = 64/123 (52%) Frame = -2 Query: 710 RHGDKIDHDILAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIV 531 R +I+ D LA++ L CIKE+LRLHPP+ + R D + +G+ IPKG I Sbjct: 365 REPKEIEWDDLAQLPFLTMCIKESLRLHPPVPAVSRCCTQD--IVLPDGRV--IPKGIIC 420 Query: 530 ATSPAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQI 351 S + P ++ +P+ YDP RF + K ++I F G C+G+ FA ++ Sbjct: 421 LISVFGTHHNPAVWPDPEVYDPFRF--DPKNIKERSPLAFIPFSAGPRNCIGQAFAMAEM 478 Query: 350 KAI 342 K + Sbjct: 479 KVV 481
>C77A3_SOYBN (O48928) Cytochrome P450 77A3 (EC 1.14.-.-)| Length = 513 Score = 65.5 bits (158), Expect = 2e-10 Identities = 45/143 (31%), Positives = 72/143 (50%), Gaps = 3/143 (2%) Frame = -2 Query: 698 KIDHDILAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIP-KGHIVATS 522 K+D + +M L+ +KE LR HPP +L +H+ TT G +DIP ++ + Sbjct: 348 KVDEKDVEKMPYLHAVVKELLRKHPPTHFVL--THAVTEPTTLGG--YDIPIDANVEVYT 403 Query: 521 PAFANRLPHIFKNPDSYDPDRFAAGREEDKVAG--AFSYISFGGGRHGCLGEPFAYLQIK 348 PA A P + NP+ +DP+RF +G EE + G + FG GR C G A + I Sbjct: 404 PAIAED-PKNWLNPEKFDPERFISGGEEADITGVTGVKMMPFGVGRRICPGLAMATVHIH 462 Query: 347 AIWTHLLRNFEFELVSPFPENDW 279 + +++ FE+ P + D+ Sbjct: 463 LMMARMVQEFEWGAYPPEKKMDF 485
>C97B2_SOYBN (O48921) Cytochrome P450 97B2 (EC 1.14.-.-)| Length = 576 Score = 65.5 bits (158), Expect = 2e-10 Identities = 43/148 (29%), Positives = 73/148 (49%), Gaps = 23/148 (15%) Frame = -2 Query: 680 LAEMDVLYRCIKEALRLHPPLIMLLRQS-HSDFSVTTREGKE--FDIPKGHIVATSPAFA 510 L E+ + + EALRL+P +L+R+S SD +G++ + IP G V S Sbjct: 397 LKELQYIRLIVVEALRLYPQPPLLIRRSLKSDVLPGGHKGEKDGYAIPAGTDVFISVYNL 456 Query: 509 NRLPHIFKNPDSYDPDRFAAGREEDKVAG--------------------AFSYISFGGGR 390 +R P+ + PD ++P+RF + +++ G F+++ FGGG Sbjct: 457 HRSPYFWDRPDDFEPERFLVQNKNEEIEGWAGLDPSRSPGALYPNEVISDFAFLPFGGGP 516 Query: 389 HGCLGEPFAYLQIKAIWTHLLRNFEFEL 306 C+G+ FA ++ T LL+NF+ EL Sbjct: 517 RKCVGDQFALMESTVALTMLLQNFDVEL 544
>CP4C3_DROME (Q9VA27) Cytochrome P450 4c3 (EC 1.14.-.-) (CYPIVC3)| Length = 535 Score = 65.5 bits (158), Expect = 2e-10 Identities = 41/130 (31%), Positives = 64/130 (49%), Gaps = 4/130 (3%) Frame = -2 Query: 680 LAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFANRL 501 L +M L CIK++LRL P + M+ R D ++ + +P G +R Sbjct: 389 LMDMRYLECCIKDSLRLFPSVPMMARMVGEDVNIGGKI-----VPAGTQAIIMTYALHRN 443 Query: 500 PHIFKNPDSYDPDRF----AAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTH 333 P +F P+ ++PD F AGR F+YI F G C+G+ FA L+ KA+ + Sbjct: 444 PRVFPKPEQFNPDNFLPENCAGRHP------FAYIPFSAGPRNCIGQKFAILEEKAVIST 497 Query: 332 LLRNFEFELV 303 +LR ++ E V Sbjct: 498 VLRKYKIEAV 507
>T10H_TAXCU (Q9AXM6) Taxane 10-beta-hydroxylase (EC 1.14.13.76)| (5-alpha-taxadienol-10-beta-hydroxylase) (Cytochrome P450 725A1) Length = 497 Score = 65.1 bits (157), Expect = 2e-10 Identities = 36/131 (27%), Positives = 65/131 (49%) Frame = -2 Query: 710 RHGDKIDHDILAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIV 531 + G++I L M ++ ++E+LR++PP+ + R++ +D + IPKG V Sbjct: 342 KEGEEISWKDLKSMKYTWQAVQESLRMYPPVFGIFRKAITDIHYDG-----YTIPKGWRV 396 Query: 530 ATSPAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQI 351 SP + F P+ + P RF +E + ++Y+ FGGG C G F+ ++I Sbjct: 397 LCSPYTTHLREEYFPEPEEFRPSRF---EDEGRHVTPYTYVPFGGGLRTCPGWEFSKIEI 453 Query: 350 KAIWTHLLRNF 318 H ++NF Sbjct: 454 LLFVHHFVKNF 464
>CP6B2_HELAM (Q27664) Cytochrome P450 6B2 (EC 1.14.14.1) (CYPVIB2)| Length = 504 Score = 65.1 bits (157), Expect = 2e-10 Identities = 50/168 (29%), Positives = 77/168 (45%), Gaps = 6/168 (3%) Frame = -2 Query: 707 HGDKIDHDILAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVA 528 +G K+ +D + +M L + E LR++ + L R++ D+ + G + I K +V Sbjct: 342 NGGKVTYDTVKDMKYLNKVFDETLRMYSIVEPLQRKAIRDYKLP---GTDVVIEKDTVVL 398 Query: 527 TSPAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIK 348 SP + P + NP ++P+RF A EE +Y+ FG G+ C+G F LQ Sbjct: 399 ISPRGIHYDPKYYDNPKQFNPERFFA--EEVGKRHPCAYLPFGLGQRNCIGMRFGRLQSL 456 Query: 347 AIWTHLLRNFEFELVSPFPENDWNAMV------VGIKGEVMVNYKRRK 222 T LL F E P D N V +G KG + +N RK Sbjct: 457 LCITKLLSKFRLE---PSKNTDRNLQVEPYRFIIGPKGGIRLNIVPRK 501
>CP9E2_BLAGE (Q964T2) Cytochrome P450 9e2 (EC 1.14.-.-) (CYPIXE2)| Length = 533 Score = 65.1 bits (157), Expect = 2e-10 Identities = 37/136 (27%), Positives = 66/136 (48%) Frame = -2 Query: 698 KIDHDILAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSP 519 K+ ++ + M L + E+LRL+PP I R+ ++ + + + G V Sbjct: 374 KLTYEAIHSMKYLDMVVSESLRLYPPAIFTDRKCVKNYRLPMEPS--YTLEPGDAVWIPI 431 Query: 518 AFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIW 339 + P + NP+ +DP+RF+ +++ F+Y+ FG G C+G FA ++ K Sbjct: 432 YAIHHDPKYYPNPEKFDPERFSDENKDN--IKPFTYLPFGSGPRNCIGNRFALMESKIAL 489 Query: 338 THLLRNFEFELVSPFP 291 HLL F ++VS P Sbjct: 490 VHLLCRFNLKVVSKTP 505
>CP3AT_PIG (P79401) Cytochrome P450 3A29 (EC 1.14.14.1) (CYPIIIA29)| Length = 503 Score = 65.1 bits (157), Expect = 2e-10 Identities = 36/127 (28%), Positives = 62/127 (48%) Frame = -2 Query: 689 HDILAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFA 510 +D LA+M+ L + E LRL+P L R D + +PKG +V Sbjct: 347 YDALAQMEYLDMVVNETLRLYPIAARLERACKKDVEI-----HGVFVPKGTVVVVPVFVL 401 Query: 509 NRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHL 330 +R P ++ P+ + P+RF+ ++ ++Y+ FG G C+G FA + +K + Sbjct: 402 HRDPDLWPEPEEFRPERFS--KKHKDTINPYTYLPFGTGPRNCIGMRFALMNMKLALVRV 459 Query: 329 LRNFEFE 309 L+NF F+ Sbjct: 460 LQNFSFK 466
>CP4A7_RABIT (P14581) Cytochrome P450 4A7 precursor (EC 1.14.15.3) (CYPIVA7)| (Lauric acid omega-hydroxylase) (P450-KA-2) Length = 511 Score = 65.1 bits (157), Expect = 2e-10 Identities = 43/130 (33%), Positives = 66/130 (50%) Frame = -2 Query: 704 GDKIDHDILAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVAT 525 G I + L +M CIKEALRL+PP+ + + S VT +G+ +PKG I+ Sbjct: 359 GASITWEHLDKMPYTTMCIKEALRLYPPVPGVGSKLSSP--VTFPDGRS--LPKGIIITL 414 Query: 524 SPAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKA 345 S + P ++ NP+ +DP RFA G + +++ F GG C+G+ FA ++K Sbjct: 415 SIYGLHHNPKVWPNPEVFDPSRFAPG----SARHSHAFLPFSGGSRNCIGKQFAMNELKV 470 Query: 344 IWTHLLRNFE 315 L FE Sbjct: 471 AVALTLVRFE 480
>CP39A_MOUSE (Q9JKJ9) Cytochrome P450 39A1 (EC 1.14.13.99)| (24-hydroxycholesterol 7-alpha-hydroxylase) (Oxysterol 7-alpha-hydroxylase) (mCYP39A1) Length = 470 Score = 64.7 bits (156), Expect = 3e-10 Identities = 44/161 (27%), Positives = 80/161 (49%), Gaps = 3/161 (1%) Frame = -2 Query: 698 KIDHDILAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSP 519 K+ D L ++ ++ CI E++RL P ++ + V + +P G ++ SP Sbjct: 317 KVSEDDLKKLLIIKWCILESVRLRAPGVITRKV------VKPVKILNHTVPSGDLLMLSP 370 Query: 518 AFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIW 339 + +R P F P+S+ P+R+ DK +++FGGG+ C G FA L+I+ Sbjct: 371 FWLHRNPKYFPEPESFKPERWKEANL-DKYIFLDYFMAFGGGKFQCPGRWFALLEIQLCI 429 Query: 338 THLLRNFEFELVSPFPENDWNAMVVGI---KGEVMVNYKRR 225 +L +E L+ P P+ + +VG+ G+ + YK+R Sbjct: 430 ILVLYKYECSLLDPLPKQS-SRHLVGVPQPAGKCRIEYKQR 469
>CP4F8_HUMAN (P98187) Cytochrome P450 4F8 (EC 1.14.14.1) (CYPIVF8)| Length = 520 Score = 64.7 bits (156), Expect = 3e-10 Identities = 39/131 (29%), Positives = 63/131 (48%) Frame = -2 Query: 710 RHGDKIDHDILAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIV 531 R +I+ D LA++ L C+KE+LRLHPP+ R D + IPKG++ Sbjct: 365 REPKEIEWDDLAQLPFLTMCLKESLRLHPPIPTFARGCTQDVVLPDSR----VIPKGNVC 420 Query: 530 ATSPAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQI 351 + + P ++ +P+ YDP RF E + ++I F G C+G+ FA ++ Sbjct: 421 NINIFAIHHNPSVWPDPEVYDPFRF--DPENAQKRSPMAFIPFSAGPRNCIGQKFAMAEM 478 Query: 350 KAIWTHLLRNF 318 K + L F Sbjct: 479 KVVLALTLLRF 489
>CP11A_CAPHI (P79153) Cytochrome P450 11A1, mitochondrial precursor (EC| 1.14.15.6) (CYPXIA1) (P450(scc)) (Cholesterol side-chain cleavage enzyme) (Cholesterol desmolase) Length = 520 Score = 64.7 bits (156), Expect = 3e-10 Identities = 41/126 (32%), Positives = 64/126 (50%) Frame = -2 Query: 683 ILAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFANR 504 +L + +L IKE LRLHP + L R SD + +++ IP +V + R Sbjct: 369 MLQMVPLLKASIKETLRLHPISVTLQRYPESDLVL-----QDYLIPAKTLVQVAIYAMGR 423 Query: 503 LPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLR 324 P F NPD +DP R+ G+++D + F + FG G C+G A L++ H+L Sbjct: 424 DPAFFSNPDKFDPTRWL-GKDKDLIH--FRNLGFGWGVRQCVGRRIAELEMTLFLIHILE 480 Query: 323 NFEFEL 306 NF+ E+ Sbjct: 481 NFKIEM 486
>CP26A_XENLA (O93323) Cytochrome P450 26A1 (EC 1.14.-.-) (Retinoic acid| degrading enzyme CYP26) (xCYP26) (Retinoic acid-converting enzyme) (RACE) Length = 492 Score = 64.7 bits (156), Expect = 3e-10 Identities = 42/132 (31%), Positives = 65/132 (49%) Frame = -2 Query: 686 DILAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFAN 507 ++L ++ IKE LRL PP+ R + F + + IPKG V S A + Sbjct: 343 EVLQQLKYTSCVIKETLRLSPPVAGGFRVALKTFVLNG-----YQIPKGWNVIYSIADTH 397 Query: 506 RLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLL 327 +F + D ++PDRF D + F +I FGGG C+G+ FA + +K L Sbjct: 398 GEADLFPDTDKFNPDRFLTPLPRD--SSRFGFIPFGGGVRCCIGKEFAKILLKVFVVELC 455 Query: 326 RNFEFELVSPFP 291 RN ++EL++ P Sbjct: 456 RNCDWELLNGSP 467
>CP4AC_RAT (P24464) Cytochrome P450 4A12 (EC 1.14.14.1) (CYPIVA12) (CYPIVA8)| (P450-KP1) (P450-PP1) Length = 508 Score = 64.3 bits (155), Expect = 3e-10 Identities = 43/130 (33%), Positives = 65/130 (50%) Frame = -2 Query: 704 GDKIDHDILAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVAT 525 G I D L +M CIKEALR++PP+ + R + VT +G+ +PKG V Sbjct: 356 GASITWDDLDKMPYTTMCIKEALRIYPPVTAVSRMLST--PVTFPDGR--SLPKGITVML 411 Query: 524 SPAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKA 345 S + P ++ NP+ +DP RFA + + S++ F GG C+G+ FA ++K Sbjct: 412 SFYGLHHNPTVWPNPEVFDPYRFA----PESSRHSHSFLPFSGGARNCIGKQFAMNELKV 467 Query: 344 IWTHLLRNFE 315 L FE Sbjct: 468 AVALTLLRFE 477
>CP26B_BRARE (Q6EIG3) Cytochrome P450 26B1 (EC 1.14.-.-) (Cyp26B1)| (Retinoic-acid metabolizing cytochrome) Length = 511 Score = 64.3 bits (155), Expect = 3e-10 Identities = 44/127 (34%), Positives = 64/127 (50%) Frame = -2 Query: 686 DILAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFAN 507 D + + L IKE LRL P+ R + F + +G + +PKG V S + Sbjct: 345 DSIISLKYLDCVIKEVLRLFAPVSGGYRIATQTFEL---DGVQ--VPKGWSVMYSIRDTH 399 Query: 506 RLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLL 327 +FK+ +++DPDRF+ R ED+ G F Y+ FGGG CLG+ A L +K + L Sbjct: 400 DTSAVFKDVEAFDPDRFSPERSEDR-EGRFHYLPFGGGVRSCLGKQLATLFLKLLAVELA 458 Query: 326 RNFEFEL 306 FEL Sbjct: 459 GGSRFEL 465
>CP46A_MOUSE (Q9WVK8) Cytochrome p450 46A1 (EC 1.14.13.98) (Cholesterol| 24-hydroxylase) (CH24H) Length = 500 Score = 64.3 bits (155), Expect = 3e-10 Identities = 38/131 (29%), Positives = 66/131 (50%) Frame = -2 Query: 695 IDHDILAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPA 516 +D++ L + L + +KE+LRL+PP R + T +G +P + S Sbjct: 342 LDYEDLGRLQYLSQVLKESLRLYPPAWGTFRLLEEE---TLIDGVR--VPGNTPLLFSTY 396 Query: 515 FANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWT 336 R+ F++P +++PDRF G + + F+Y F G C+G+ FA +++K + Sbjct: 397 VMGRMDTYFEDPLTFNPDRFGPGAPKPR----FTYFPFSLGHRSCIGQQFAQMEVKVVMA 452 Query: 335 HLLRNFEFELV 303 LL+ EF LV Sbjct: 453 KLLQRIEFRLV 463
>CP11A_SHEEP (P79202) Cytochrome P450 11A1, mitochondrial precursor (EC| 1.14.15.6) (CYPXIA1) (P450(SCC)) (Cholesterol side-chain cleavage enzyme) (Cholesterol desmolase) Length = 520 Score = 63.9 bits (154), Expect = 5e-10 Identities = 41/126 (32%), Positives = 63/126 (50%) Frame = -2 Query: 683 ILAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFANR 504 +L + +L IKE LRLHP + L R SD + +++ IP +V + R Sbjct: 369 MLQMVPLLKASIKETLRLHPISVTLQRYPESDLVL-----QDYLIPAKTLVQVAIYAMGR 423 Query: 503 LPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLR 324 P F NPD +DP R+ G+++D + F + FG G C+G A L++ H+L Sbjct: 424 DPAFFSNPDKFDPTRWL-GKDKDLIH--FRNLGFGWGVRQCVGRRIAELEMTLFLIHILE 480 Query: 323 NFEFEL 306 NF E+ Sbjct: 481 NFRVEM 486
>CP3AO_SHEEP (Q29496) Cytochrome P450 3A24 (EC 1.14.14.1) (CYPIIIA24)| Length = 503 Score = 63.9 bits (154), Expect = 5e-10 Identities = 37/127 (29%), Positives = 63/127 (49%) Frame = -2 Query: 689 HDILAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFA 510 +D+LA+M+ L + E LR+ P + L R D + IPKG V Sbjct: 347 YDVLAQMEYLDMVVNETLRMFPIAVRLDRLCKKDVEI-----HGVSIPKGTAVTVPIFVL 401 Query: 509 NRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHL 330 +R P ++ P+ + P+RF+ + +D + + Y+ FG G C+G FA + +K + Sbjct: 402 HRDPQLWPEPEEFRPERFSK-KNKDSI-NPYVYLPFGTGPRNCIGMRFAIMNMKLAIVRV 459 Query: 329 LRNFEFE 309 L+NF F+ Sbjct: 460 LQNFSFK 466
>CP6D4_DROME (Q9VCW1) Probable cytochrome P450 6d4 (EC 1.14.-.-) (CYPVID4)| Length = 515 Score = 63.5 bits (153), Expect = 6e-10 Identities = 40/137 (29%), Positives = 70/137 (51%) Frame = -2 Query: 710 RHGDKIDHDILAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIV 531 ++ KI +D L +M+ L C++E +R +P L +L R+ D++V IPKG V Sbjct: 354 KNDGKITYDSLNKMEFLDLCVQETIRKYPGLPILNRECTQDYTVPDTNHV---IPKGTPV 410 Query: 530 ATSPAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQI 351 S + F +P++YDP+RF+ EE + +++ FG G C+ + + Sbjct: 411 VISLYGIHHDAEYFPDPETYDPERFS---EESRNYNPTAFMPFGEGPRICIAQRMGRINS 467 Query: 350 KAIWTHLLRNFEFELVS 300 K +L+NF E++S Sbjct: 468 KLAIIKILQNFNVEVMS 484
>CP9H1_DROME (Q9V6H1) Probable cytochrome P450 9h1 (EC 1.14.-.-) (CYPIXH1)| Length = 518 Score = 63.5 bits (153), Expect = 6e-10 Identities = 41/132 (31%), Positives = 66/132 (50%), Gaps = 2/132 (1%) Frame = -2 Query: 704 GDKIDHDILAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKE-FDIPKGHIVA 528 G + +D L +M L + EALR PP I R+ D + G++ F KG ++ Sbjct: 358 GQPLTYDKLTKMKYLDMVVLEALRKWPPSISTDRECRQDIDLFDENGQKLFSARKGDVLQ 417 Query: 527 TSPAFANRLPHIFKNPDSYDPDRFAAGRE-EDKVAGAFSYISFGGGRHGCLGEPFAYLQI 351 + P F++P+ ++P+RFA G E +V Y+ FG G C+G A +++ Sbjct: 418 IPIFSLHHDPENFEDPEFFNPERFADGHALESRV-----YMPFGVGPRNCIGNRMALMEL 472 Query: 350 KAIWTHLLRNFE 315 K+I LL NF+ Sbjct: 473 KSIVYQLLLNFK 484
>CP317_DROME (Q9V776) Probable cytochrome P450 317a1 (EC 1.14.-.-)| (CYPCCCXVIIA1) Length = 518 Score = 63.5 bits (153), Expect = 6e-10 Identities = 37/135 (27%), Positives = 69/135 (51%) Frame = -2 Query: 710 RHGDKIDHDILAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIV 531 RH I H+ + + + + I E LR+HP +LR++ +D++V + ++ + K + Sbjct: 356 RHDGHITHEGIKSLSFMGQVINETLRMHPITPYILRRTLNDYAVP--DHPKYILVKELFL 413 Query: 530 ATSPAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQI 351 + P I+ +P+ + PDR++ R+ + G ++ FG G C+G FA LQ+ Sbjct: 414 IIPTHAIHHDPDIYPDPEEFKPDRWSGPRDSLQEQG--TWFGFGVGARSCIGIQFAQLQL 471 Query: 350 KAIWTHLLRNFEFEL 306 + LL +EF L Sbjct: 472 RLALALLLSEYEFSL 486
>CP4S3_DROME (Q9VXY0) Probable cytochrome P450 4s3 (EC 1.14.-.-) (CYPIVS3)| Length = 495 Score = 63.5 bits (153), Expect = 6e-10 Identities = 39/120 (32%), Positives = 60/120 (50%) Frame = -2 Query: 671 MDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFANRLPHI 492 M L IKE LR++P + R+ D V GK +PKG ++ +R P Sbjct: 348 MPYLEAVIKETLRIYPSVPFFSRKVLEDLEV----GK-LTVPKGASISCLIYMLHRDPKN 402 Query: 491 FKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEF 312 F +P+ +DPDRF +K F++ +F G C+G+ FA L++K LLR++ F Sbjct: 403 FPDPERFDPDRFLVN---EKQMHPFAFAAFSAGPRNCIGQKFAMLELKTSLAMLLRSYRF 459
>CP3A9_RAT (P51538) Cytochrome P450 3A9 (EC 1.14.14.1) (CYPIIIA9) (P450-OLF3)| (Olfactive) (3AH15) Length = 503 Score = 63.5 bits (153), Expect = 6e-10 Identities = 36/127 (28%), Positives = 62/127 (48%) Frame = -2 Query: 689 HDILAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFA 510 +D L +M+ L + E LRL+P L R +D + IPKG +V Sbjct: 347 YDTLLQMEYLDMVVNETLRLYPIAGRLERVCKTDVEING-----VFIPKGTVVMIPTFAL 401 Query: 509 NRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHL 330 ++ PH + P+ + P+RF+ +++ + Y+ FG G C+G FA + +K + Sbjct: 402 HKDPHYWPEPEEFRPERFSKKNQDN--INPYMYLPFGNGPRNCIGMRFALMNMKVALFRV 459 Query: 329 LRNFEFE 309 L+NF F+ Sbjct: 460 LQNFSFQ 466
>C28A5_DROME (Q9V419) Probable cytochrome P450 28a5 (EC 1.14.-.-) (CYPXXVIIIA5)| Length = 505 Score = 63.5 bits (153), Expect = 6e-10 Identities = 41/155 (26%), Positives = 72/155 (46%), Gaps = 4/155 (2%) Frame = -2 Query: 680 LAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFANRL 501 L+++ L C++E +RL PP M + + +EG F + KG V P + L Sbjct: 351 LSDLPYLDACVQETIRLFPPGFMSNKLCTESIEIPNKEGPNFVVEKGTTVVV-PHYCFML 409 Query: 500 -PHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLR 324 F NP S+ P+RF ++ FG G C+G FA +QIKA L+ Sbjct: 410 DEEFFPNPQSFQPERFLEPDAAKTFRERGVFMGFGDGPRVCIGMRFATVQIKAAIVELIS 469 Query: 323 NFEFELVSPF-PENDW--NAMVVGIKGEVMVNYKR 228 F ++ +ND+ ++ G++G + ++ ++ Sbjct: 470 KFNVKINDKTRKDNDYEPGQIITGLRGGIWLDLEK 504
>CP3A6_RABIT (P11707) Cytochrome P450 3A6 (EC 1.14.14.1) (CYPIIIA6) (P450-3C)| Length = 501 Score = 63.5 bits (153), Expect = 6e-10 Identities = 41/128 (32%), Positives = 60/128 (46%) Frame = -2 Query: 689 HDILAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFA 510 +D L +M+ L + E LRL+P L R D + IPKG IV Sbjct: 345 YDTLVKMEYLDMVVNETLRLYPIAGRLERVCKKDVDINGTF-----IPKGTIVMMPTYAL 399 Query: 509 NRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHL 330 +R P + PD + P+RF+ +++ + Y FG G CLG FA + IK L Sbjct: 400 HRDPQHWTEPDEFRPERFSKKNKDN--INPYIYHPFGAGPRNCLGMRFALMNIKLALVRL 457 Query: 329 LRNFEFEL 306 ++NF F+L Sbjct: 458 MQNFSFKL 465
>CP120_SYNY3 (Q59990) Putative cytochrome P450 120 (EC 1.14.-.-)| Length = 444 Score = 63.2 bits (152), Expect = 8e-10 Identities = 38/128 (29%), Positives = 67/128 (52%) Frame = -2 Query: 686 DILAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFAN 507 + L +M L + ++E LRL PP+ R+ D + F PKG +V+ + + Sbjct: 296 ETLKKMPYLDQVLQEVLRLIPPVGGGFRELIQDCQF-----QGFHFPKGWLVSYQISQTH 350 Query: 506 RLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLL 327 P ++ +P+ +DP+RF F+++ FGGG CLG+ FA L++K T L+ Sbjct: 351 ADPDLYPDPEKFDPERFTPDGSATHNP-PFAHVPFGGGLRECLGKEFARLEMKLFATRLI 409 Query: 326 RNFEFELV 303 + F++ L+ Sbjct: 410 QQFDWTLL 417
>CP3AH_CAVPO (Q64409) Cytochrome P450 3A17 (EC 1.14.14.1) (CYPIIIA17)| Length = 503 Score = 63.2 bits (152), Expect = 8e-10 Identities = 42/127 (33%), Positives = 64/127 (50%), Gaps = 1/127 (0%) Frame = -2 Query: 689 HDILAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFA 510 +D++ EM+ L + E LRL+P + R S DF + G F PKG V P+FA Sbjct: 347 YDVMMEMEYLDMVVNETLRLYPVTNRIERMSKKDFEIN---GMSF--PKGTGVMI-PSFA 400 Query: 509 -NRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTH 333 +R + PD + P+RF+ +E+ + Y+ FG G C+G A + +K Sbjct: 401 LHRDSKYWPEPDEFRPERFSKKNKEN--IDPYIYMPFGNGPRNCIGMRMALMNLKLALIR 458 Query: 332 LLRNFEF 312 LL+NF F Sbjct: 459 LLQNFSF 465
>CP3AE_CAVPO (Q64417) Cytochrome P450 3A14 (EC 1.14.14.1) (CYPIIIA14)| Length = 503 Score = 63.2 bits (152), Expect = 8e-10 Identities = 42/127 (33%), Positives = 64/127 (50%), Gaps = 1/127 (0%) Frame = -2 Query: 689 HDILAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFA 510 +D++ EM+ L + E LRL+P + R S DF + G F PKG V P+FA Sbjct: 347 YDVMMEMEYLDMVVNETLRLYPVTNRIERMSKKDFEIN---GMSF--PKGTGVMI-PSFA 400 Query: 509 -NRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTH 333 +R + PD + P+RF+ +E+ + Y+ FG G C+G A + +K Sbjct: 401 LHRDSKYWPEPDEFRPERFSKKNKEN--IDPYIYMPFGNGPRNCIGMRMALMNLKLALIR 458 Query: 332 LLRNFEF 312 LL+NF F Sbjct: 459 LLQNFSF 465
>C76A1_SOLME (P37121) Cytochrome P450 76A1 (EC 1.14.-.-) (CYPLXXVIA1) (P-450EG8)| (Fragment) Length = 467 Score = 63.2 bits (152), Expect = 8e-10 Identities = 44/138 (31%), Positives = 68/138 (49%), Gaps = 3/138 (2%) Frame = -2 Query: 701 DKIDHDILAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATS 522 ++ D D L M + +KE LRLHPPL +L+ + ++ + +DIPKG V + Sbjct: 312 EECDIDSLPYMQAV---LKEQLRLHPPLPLLIPRK----AIQDTKFMGYDIPKGTQVLVN 364 Query: 521 PAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAI 342 R P + NP + P+RF + + K + I FG GR C+G P + + Sbjct: 365 AWAIGRDPEYWDNPFEFKPERFLESKVDVKGQN-YELIPFGAGRRMCVGLPLGHRMMHFT 423 Query: 341 WTHLLRNFEFEL---VSP 297 + LL F++EL VSP Sbjct: 424 FGSLLHEFDWELPHNVSP 441
>CP6J1_BLAGE (Q964R1) Cytochrome P450 6j1 (EC 1.14.-.-) (CYPVIJ1)| Length = 501 Score = 63.2 bits (152), Expect = 8e-10 Identities = 41/140 (29%), Positives = 68/140 (48%) Frame = -2 Query: 707 HGDKIDHDILAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVA 528 H K+ + + +M L + E LR +P + L R+ D+ +T ++ +P G V Sbjct: 342 HKKKVTYYSIKDMKYLDMVVNETLRKYPAIPFLDRRCQEDYPLT----QDLMLPAGTGVY 397 Query: 527 TSPAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIK 348 + F +P +DP+RF+ +++ F+Y+ FG G C+G F +Q+K Sbjct: 398 IPVYALHHDSKYFPSPAKFDPERFSEKNKQN--IPHFAYMPFGEGPRNCIGMRFGSMQVK 455 Query: 347 AIWTHLLRNFEFELVSPFPE 288 A H+L NFE VSP E Sbjct: 456 AALIHILSNFE---VSPCKE 472
>CP46A_HUMAN (Q9Y6A2) Cytochrome p450 46A1 (EC 1.14.13.98) (Cholesterol| 24-hydroxylase) (CH24H) Length = 500 Score = 63.2 bits (152), Expect = 8e-10 Identities = 38/131 (29%), Positives = 65/131 (49%) Frame = -2 Query: 695 IDHDILAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPA 516 +D + L + L + +KE+LRL+PP R + T +G +P + S Sbjct: 342 LDFEDLGRLQYLSQVLKESLRLYPPAWGTFRLLEEE---TLIDGVR--VPGNTPLLFSTY 396 Query: 515 FANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWT 336 R+ F++P +++PDRF G + + F+Y F G C+G+ FA +++K + Sbjct: 397 VMGRMDTYFEDPLTFNPDRFGPGAPKPR----FTYFPFSLGHRSCIGQQFAQMEVKVVMA 452 Query: 335 HLLRNFEFELV 303 LL+ EF LV Sbjct: 453 KLLQRLEFRLV 463
>C71B3_ARATH (O65785) Cytochrome P450 71B3 (EC 1.14.-.-)| Length = 501 Score = 62.8 bits (151), Expect = 1e-09 Identities = 39/133 (29%), Positives = 70/133 (52%), Gaps = 1/133 (0%) Frame = -2 Query: 701 DKIDHDILAEMDVLYRCIKEALRLHPPLIMLL-RQSHSDFSVTTREGKEFDIPKGHIVAT 525 ++I+ + + ++ L IKE LRLHPP +LL R++ +D + + +DIP+ I+ Sbjct: 344 ERIEEEDVDKLQYLKLVIKETLRLHPPAPLLLPRETMADIKI-----QGYDIPRKTILLV 398 Query: 524 SPAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKA 345 + R P +++NP+ ++P+RF D +F + FG GR C G F ++ Sbjct: 399 NAWSIGRNPELWENPEEFNPERF-IDCPMDYKGNSFEMLPFGSGRKICPGIAFGIATVEL 457 Query: 344 IWTHLLRNFEFEL 306 +LL F++ L Sbjct: 458 GLLNLLYYFDWRL 470
>CP3AR_ONCMY (O42563) Cytochrome P450 3A27 (EC 1.14.14.1) (CYPIIIA27)| Length = 518 Score = 62.8 bits (151), Expect = 1e-09 Identities = 40/130 (30%), Positives = 65/130 (50%) Frame = -2 Query: 695 IDHDILAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPA 516 I ++ L +MD L + E+LRL+P L R + T E IPK IV Sbjct: 350 IQYEALMQMDYLDCVLNESLRLYPIAPRLERVAKK-----TVEINGIVIPKDCIVLVPTW 404 Query: 515 FANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWT 336 +R P I+ +P+ + P+RF+ +E + ++Y+ FG G C+G FA + IK Sbjct: 405 TLHRDPEIWSDPEEFKPERFS--KENKESIDPYTYMPFGAGPRNCIGMRFALIMIKLAMV 462 Query: 335 HLLRNFEFEL 306 +L++F F + Sbjct: 463 EILQSFTFSV 472
>CP11A_MESAU (Q9EPT4) Cytochrome P450 11A1, mitochondrial precursor (EC| 1.14.15.6) (CYPXIA1) (P450(scc)) (Cholesterol side-chain cleavage enzyme) (Cholesterol desmolase) Length = 520 Score = 62.8 bits (151), Expect = 1e-09 Identities = 41/122 (33%), Positives = 58/122 (47%) Frame = -2 Query: 665 VLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFANRLPHIFK 486 +L IKE LRLHP + + R D + + + IP +V + R P F Sbjct: 372 LLKASIKETLRLHPISVTVQRYLVDDLVL-----RNYRIPAKMLVQVANYAMGREPSFFP 426 Query: 485 NPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFEL 306 NP+ +DP R+ E+ K F Y+SFG G CLG A L++ ++L NF EL Sbjct: 427 NPNKFDPTRWL---EKSKNTTHFRYLSFGWGVRQCLGRRIAELEMTIFLINVLENFRIEL 483 Query: 305 VS 300 S Sbjct: 484 QS 485
>C76A2_SOLME (P37122) Cytochrome P450 76A2 (EC 1.14.-.-) (CYPLXXVIA2) (P-450EG7)| Length = 505 Score = 62.8 bits (151), Expect = 1e-09 Identities = 42/137 (30%), Positives = 66/137 (48%), Gaps = 3/137 (2%) Frame = -2 Query: 698 KIDHDILAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSP 519 K + + + + +KE+LRLHPPL L+ + ++ + +D+PK V + Sbjct: 348 KFEDSDIENLPYMQAVLKESLRLHPPLPFLIPRE----TIQDTKFMGYDVPKDTQVLVNA 403 Query: 518 AFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIW 339 R P + +P S+ P+RF G + D + I FG GR C+G P + + Sbjct: 404 WAIGRDPECWDDPMSFKPERFL-GSKIDVKGQHYGLIPFGAGRRMCVGLPLGHRMMHFAL 462 Query: 338 THLLRNFEFEL---VSP 297 LLR FE+EL VSP Sbjct: 463 GSLLREFEWELPDGVSP 479
>CP4B1_MOUSE (Q64462) Cytochrome P450 4B1 (EC 1.14.14.1) (CYPIVB1)| Length = 511 Score = 62.8 bits (151), Expect = 1e-09 Identities = 42/137 (30%), Positives = 68/137 (49%) Frame = -2 Query: 701 DKIDHDILAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATS 522 D D LA+M L C+KE RL+PP+ + RQ VT +G+ +P G +++ Sbjct: 353 DSFQWDDLAQMTYLTMCMKECFRLYPPVPQVYRQLSK--PVTFVDGR--SLPAGSLISLH 408 Query: 521 PAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAI 342 +R ++ +P+ +DP RF+ E F+++ F G C+G+ FA ++K + Sbjct: 409 IYALHRNSAVWPDPEVFDPLRFSP--ENMTGRHPFAFMPFSAGPRNCIGQQFAMNEMKVV 466 Query: 341 WTHLLRNFEFELVSPFP 291 L FEF SP P Sbjct: 467 TALCLLRFEF---SPDP 480
>C77A2_SOLME (P37124) Cytochrome P450 77A2 (EC 1.14.-.-) (CYPLXXVIIA2)| (P-450EG5) Length = 511 Score = 62.8 bits (151), Expect = 1e-09 Identities = 42/132 (31%), Positives = 64/132 (48%), Gaps = 2/132 (1%) Frame = -2 Query: 701 DKIDHDILAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATS 522 +KID + +M L +KE LR HPP M L +H+ G +DIP G V Sbjct: 352 NKIDEKDIEKMPYLNAVVKELLRKHPPTYMSL--THAVTEPAKLGG--YDIPTGVNVEIF 407 Query: 521 PAFANRLPHIFKNPDSYDPDRFAAGREEDKVAG--AFSYISFGGGRHGCLGEPFAYLQIK 348 + P+++ P+ +DPDRF G+E+ + G I FG GR C G A + + Sbjct: 408 LPGISDDPNLWSEPEKFDPDRFYLGKEDADITGVSGVKMIPFGMGRRICPGLNMATVHVS 467 Query: 347 AIWTHLLRNFEF 312 + L++ FE+ Sbjct: 468 LMLARLVQEFEW 479
>C71BP_ARATH (Q9LTL2) Cytochrome P450 71B25 (EC 1.14.-.-)| Length = 501 Score = 62.4 bits (150), Expect = 1e-09 Identities = 40/133 (30%), Positives = 70/133 (52%), Gaps = 1/133 (0%) Frame = -2 Query: 701 DKIDHDILAEMDVLYRCIKEALRLHPPLIMLL-RQSHSDFSVTTREGKEFDIPKGHIVAT 525 ++I+ + + ++ L IKE LRLHP +LL R++ +D + + +DIP+ ++ Sbjct: 344 ERIEEEDVGKLQYLKLVIKETLRLHPAAPLLLPRETMADIKI-----QGYDIPRKTLLLV 398 Query: 524 SPAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKA 345 S R P +KNP+ ++P+RF D +F ++ FG GR C G A I+ Sbjct: 399 SAWSLGRDPKYWKNPEEFNPERF-IDCPVDYKGHSFEFLPFGSGRRFCPGMASAIATIEL 457 Query: 344 IWTHLLRNFEFEL 306 +LL F+++L Sbjct: 458 TLLNLLYFFDWKL 470
>C28D2_DROME (Q9VMT6) Probable cytochrome P450 28d2 (EC 1.14.-.-) (CYPXXVIIID2)| Length = 501 Score = 62.4 bits (150), Expect = 1e-09 Identities = 43/160 (26%), Positives = 74/160 (46%), Gaps = 8/160 (5%) Frame = -2 Query: 686 DILAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFAN 507 D ++E+ L CI E LRL P + + F + G+ + G +V + Sbjct: 343 DQMSELPHLDACIYETLRLFSPQVAARKLVTEPFEFANKNGRTVHLKPGDVVTIPVKALH 402 Query: 506 RLPHIFKNPDSYDPDRF----AAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIW 339 P +++P ++ P+RF G + + G Y++FG G C G FA Q+KA Sbjct: 403 HDPQYYEDPLTFKPERFLESNGGGMKSYRDRGV--YLAFGDGPRHCPGMRFALTQLKAAL 460 Query: 338 THLLRNFEFELVSPFPENDWNA----MVVGIKGEVMVNYK 231 +LRNFE + V+P +D + +KG + +++K Sbjct: 461 VEILRNFEIK-VNPKTRSDNQIDDTFFMATLKGGIYLDFK 499
>CP11A_MOUSE (Q9QZ82) Cytochrome P450 11A1, mitochondrial precursor (EC| 1.14.15.6) (CYPXIA1) (P450(scc)) (Cholesterol side-chain cleavage enzyme) (Cholesterol desmolase) Length = 526 Score = 62.4 bits (150), Expect = 1e-09 Identities = 39/120 (32%), Positives = 59/120 (49%) Frame = -2 Query: 665 VLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFANRLPHIFK 486 +L IKE LRLHP + L R + +D + + + IP +V + R P F Sbjct: 372 LLKASIKETLRLHPISVTLQRYTVNDLVL-----RNYKIPAKTLVQVASFAMGRDPGFFP 426 Query: 485 NPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFEL 306 NP+ +DP R+ E+ + F Y+ FG G CLG A L++ + +LL NF E+ Sbjct: 427 NPNKFDPTRWL---EKSQNTTHFRYLGFGWGVRQCLGRRIAELEMTILLINLLENFRIEV 483
>CP4AE_RAT (P20817) Cytochrome P450 4A14 precursor (EC 1.14.15.3) (CYPIVA14)| (Lauric acid omega-hydroxylase) (P450-LA-omega 3) Length = 507 Score = 62.4 bits (150), Expect = 1e-09 Identities = 42/130 (32%), Positives = 62/130 (47%) Frame = -2 Query: 704 GDKIDHDILAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVAT 525 G + D L ++ CIKEALRL+PP+ + R+ S VT +G+ IPKG Sbjct: 355 GTSVTWDHLDQIPYTTMCIKEALRLYPPVPSVSRELSS--PVTFPDGR--SIPKGITTTI 410 Query: 524 SPAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKA 345 + P + NP +DP RF+ D + +Y+ F GG C+G+ FA ++K Sbjct: 411 LIYGLHHNPSYWPNPKVFDPSRFS----PDSPRHSHAYLPFSGGARNCIGKQFAMNELKV 466 Query: 344 IWTHLLRNFE 315 L FE Sbjct: 467 AVALTLLRFE 476
>C4D21_DROME (Q9VLZ7) Probable cytochrome P450 4d21 (EC 1.14.-.-) (CYPIVD21)| Length = 511 Score = 62.0 bits (149), Expect = 2e-09 Identities = 38/122 (31%), Positives = 60/122 (49%) Frame = -2 Query: 680 LAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFANRL 501 L E+ L IKE +RLHPP+ +L R D + E IP + P + R Sbjct: 363 LLELKYLDCVIKETMRLHPPVPILGRYIPEDLKIG-----EITIPGNTSILLMPYYVYRD 417 Query: 500 PHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRN 321 P F +P + P+R+ + +YI F G C+G+ FA LQ+KA+ + ++R+ Sbjct: 418 PEYFPDPLVFKPERWMDMKTTSNTP-PLAYIPFSSGPKNCIGQKFANLQMKALISKVIRH 476 Query: 320 FE 315 +E Sbjct: 477 YE 478
>CP3AI_RAT (Q64581) Cytochrome P450 3A18 (EC 1.14.14.1) (CYPIIIA18)| (P450(6)beta-2) Length = 497 Score = 62.0 bits (149), Expect = 2e-09 Identities = 38/129 (29%), Positives = 62/129 (48%) Frame = -2 Query: 695 IDHDILAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPA 516 + +D L EM+ L + E+LRL+P L R S D + IPKG +V Sbjct: 345 VTYDALMEMEYLDMVVNESLRLYPIATRLDRVSKKDVEING-----VFIPKGTVVTIPIY 399 Query: 515 FANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWT 336 +R P + P+ ++P+RF+ +E + Y+ FG G C+G FA + +K Sbjct: 400 PLHRNPEYWLEPEEFNPERFS--KENKGSIDPYVYLPFGNGPRNCIGMRFALISMKLAVI 457 Query: 335 HLLRNFEFE 309 +L+NF + Sbjct: 458 GVLQNFNIQ 466
>CP4B1_RABIT (P15128) Cytochrome P450 4B1 (EC 1.14.14.1) (CYPIVB1) (P450-isozyme| 5) Length = 506 Score = 62.0 bits (149), Expect = 2e-09 Identities = 37/132 (28%), Positives = 65/132 (49%) Frame = -2 Query: 701 DKIDHDILAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATS 522 D + LA+M L C+KE RL+PP+ + RQ S +G+ +P G +++ Sbjct: 348 DSFQWEDLAKMTYLTMCMKECFRLYPPVPQVYRQLSKPVSFV--DGRS--LPAGSLISLH 403 Query: 521 PAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAI 342 +R ++ +P+ +DP RF+ E +++I F G C+G+ FA ++K + Sbjct: 404 IYALHRNSDVWPDPEVFDPLRFSP--ENSSGRHPYAFIPFSAGPRNCIGQQFAMNEMKVV 461 Query: 341 WTHLLRNFEFEL 306 L FEF + Sbjct: 462 TALCLLRFEFSV 473
>C11B1_SHEEP (P51663) Cytochrome P450 11B1, mitochondrial precursor (EC| 1.14.15.4) (CYPXIB1) (P450C11) (Steroid 11-beta-hydroxylase) Length = 503 Score = 62.0 bits (149), Expect = 2e-09 Identities = 39/125 (31%), Positives = 62/125 (49%) Frame = -2 Query: 674 EMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFANRLPH 495 E+ +L +KE LRL+P I L RQ SD + + + IP G +V R P Sbjct: 361 ELPLLRAALKETLRLYPVGITLERQVSSDLVL-----QNYHIPAGTLVKVLLYSLGRNPA 415 Query: 494 IFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFE 315 +F P+SY P R+ + F +++FG G CLG A +++ + H+L+NF Sbjct: 416 VFARPESYHPQRWL---DRQGSGSRFPHLAFGFGMRQCLGRRVAEVEMLLLLHHVLKNFL 472 Query: 314 FELVS 300 E ++ Sbjct: 473 VETLA 477
>C77A1_SOLME (P37123) Cytochrome P450 77A1 (EC 1.14.-.-) (CYPLXXVIIA1)| (P-450EG6) (Fragment) Length = 499 Score = 62.0 bits (149), Expect = 2e-09 Identities = 39/131 (29%), Positives = 64/131 (48%), Gaps = 2/131 (1%) Frame = -2 Query: 698 KIDHDILAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSP 519 K+D + + +M L +KE LR HPP L +HS G +DIP V Sbjct: 340 KVDENDIEKMPYLNAVVKELLRKHPPTYFTL--THSVTEPVKLAG--YDIPMDTNVEFFV 395 Query: 518 AFANRLPHIFKNPDSYDPDRFAAGREEDKVAGA--FSYISFGGGRHGCLGEPFAYLQIKA 345 + P+++ +P+ +DPDRF +GRE+ + G + FG GR C G A + + Sbjct: 396 HGISHDPNVWSDPEKFDPDRFLSGREDADITGVKEVKMMPFGVGRRICPGLGMATVHVNL 455 Query: 344 IWTHLLRNFEF 312 + +++ FE+ Sbjct: 456 MLARMVQEFEW 466
>C98A1_SORBI (O48956) Cytochrome P450 98A1 (EC 1.14.-.-)| Length = 512 Score = 62.0 bits (149), Expect = 2e-09 Identities = 44/132 (33%), Positives = 62/132 (46%), Gaps = 1/132 (0%) Frame = -2 Query: 662 LYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFANRLPHIFKN 483 L +KE+LRLHPP ++L S T + +DIPKG V + R P ++ N Sbjct: 353 LQAVVKESLRLHPPTPLMLPHKAS----TNVKIGGYDIPKGANVMVNVWAVARDPKVWSN 408 Query: 482 PDSYDPDRFAAGREEDKVAGA-FSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFEL 306 P Y P+RF E + G+ F + FG GR C G + ++ HLL +FE+ L Sbjct: 409 PLEYRPERFL--EENIDIKGSDFRVLPFGAGRRVCPGAQLGINLVASMIGHLLHHFEWSL 466 Query: 305 VSPFPENDWNAM 270 D N M Sbjct: 467 PEGTRPEDVNMM 478
>CP131_DROME (Q9VFJ0) Probable cytochrome P450 313a1 (EC 1.14.-.-)| (CYPCCCXIIIA1) Length = 492 Score = 62.0 bits (149), Expect = 2e-09 Identities = 38/128 (29%), Positives = 65/128 (50%), Gaps = 1/128 (0%) Frame = -2 Query: 695 IDHDILAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPA 516 I + + ++D L R IKE LRL P + + R++ +D R IPKG ++ Sbjct: 339 ITYPDMQKLDYLERVIKETLRLIPAIPITARETKND----VRLSNGVLIPKGVVIGIDMF 394 Query: 515 FANRLPHIF-KNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIW 339 +R P ++ + D+++PD F A E K ++YI F G+ C+G +A + K Sbjct: 395 HTHRNPEVWGPDADNFNPDNFLAENMEQK--HPYAYIPFARGKRNCIGSKYAMMSSKFAL 452 Query: 338 THLLRNFE 315 +LRN++ Sbjct: 453 CRILRNYK 460
>CP4E2_DROME (Q27606) Cytochrome P450 4e2 (EC 1.14.-.-) (CYPIVE2)| Length = 526 Score = 62.0 bits (149), Expect = 2e-09 Identities = 37/122 (30%), Positives = 63/122 (51%) Frame = -2 Query: 680 LAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFANRL 501 +++M L IKEA R++P + + R + D+ + +G +PKG + Sbjct: 355 ISQMKYLDLFIKEAQRVYPSVPFIGRFTEKDYVI---DGDL--VPKGTTLNLGLVMLGYN 409 Query: 500 PHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRN 321 +FK+P + P+RF E + G F Y+ F G C+G+ FA L+IK + + ++RN Sbjct: 410 EKVFKDPHKFRPERF-----ELEKPGPFEYVPFSAGPRNCIGQKFALLEIKTVVSKIIRN 464 Query: 320 FE 315 FE Sbjct: 465 FE 466
>CP4B1_HUMAN (P13584) Cytochrome P450 4B1 (EC 1.14.14.1) (CYPIVB1) (P450-HP)| Length = 511 Score = 61.6 bits (148), Expect = 2e-09 Identities = 39/132 (29%), Positives = 65/132 (49%) Frame = -2 Query: 701 DKIDHDILAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATS 522 D D L +M L CIKE+ RL+PP+ + RQ VT +G+ +P G +++ Sbjct: 353 DFFQWDDLGKMTYLTMCIKESFRLYPPVPQVYRQLSKP--VTFVDGRS--LPAGSLISMH 408 Query: 521 PAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAI 342 +R ++ +P+ +D RF+ E F+++ F G C+G+ FA ++K + Sbjct: 409 IYALHRNSAVWPDPEVFDSLRFST--ENASKRHPFAFMPFSAGPRNCIGQQFAMSEMKVV 466 Query: 341 WTHLLRNFEFEL 306 L FEF L Sbjct: 467 TAMCLLRFEFSL 478
>C6A20_DROME (Q9V773) Probable cytochrome P450 6a20 (EC 1.14.-.-) (CYPVIA20)| Length = 501 Score = 61.6 bits (148), Expect = 2e-09 Identities = 39/136 (28%), Positives = 67/136 (49%), Gaps = 2/136 (1%) Frame = -2 Query: 710 RHGDKIDHDILAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIV 531 +H K+D+D + EM L + I E +R P + L+R + + T +++I KG V Sbjct: 341 QHNGKLDYDSMREMTYLEKVIDETMRKRPVVGHLIRVATQHYQHTN---PKYNIEKGTGV 397 Query: 530 ATSPAFANRLPHIFKNPDSYDPDRFAAGREEDKVAG--AFSYISFGGGRHGCLGEPFAYL 357 + P + P+ + P+RF +ED+V A +++ FG G C+G F + Sbjct: 398 IVPTLAIHHDPEFYPEPEKFIPERF----DEDQVQQRPACTFLPFGDGPRNCIGLRFGRM 453 Query: 356 QIKAIWTHLLRNFEFE 309 Q+ L+ NF+FE Sbjct: 454 QVIVGMALLIHNFKFE 469
>CP4E1_DROME (Q9V4T5) Probable cytochrome P450 4e1 (EC 1.14.-.-) (CYPIVE1)| Length = 531 Score = 61.6 bits (148), Expect = 2e-09 Identities = 36/113 (31%), Positives = 58/113 (51%), Gaps = 1/113 (0%) Frame = -2 Query: 650 IKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDI-PKGHIVATSPAFANRLPHIFKNPDS 474 IKEA RL+P + + R + D+ + + DI PKG + +FK+P Sbjct: 365 IKEAQRLYPSVPFIGRFTEKDYVI------DGDIVPKGTTLNLGLLMLGYNDRVFKDPHK 418 Query: 473 YDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFE 315 + P+RF + + G F Y+ F G C+G+ FA L+IK + + ++RNFE Sbjct: 419 FQPERF-----DREKPGPFEYVPFSAGPRNCIGQKFALLEIKTVVSKIIRNFE 466
>CP4A2_RAT (P20816) Cytochrome P450 4A2 precursor (EC 1.14.15.3) (CYPIVA2)| (Lauric acid omega-hydroxylase) (P450-LA-omega 2) (P450 K-5) (P-450 K-2) Length = 504 Score = 61.6 bits (148), Expect = 2e-09 Identities = 43/130 (33%), Positives = 62/130 (47%) Frame = -2 Query: 704 GDKIDHDILAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVAT 525 G + D L +M CIKEALRL+ P+ + R+ S VT +G+ IPKG V Sbjct: 352 GTSVTWDHLDQMPYTTMCIKEALRLYSPVPSVSRELSSP--VTFPDGRS--IPKGIRVTI 407 Query: 524 SPAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKA 345 + P + NP +DP RF+ D + +Y+ F GG C+G+ FA ++K Sbjct: 408 LIYGLHHNPSYWPNPKVFDPSRFSP----DSPRHSHAYLPFSGGARNCIGKQFAMNELKV 463 Query: 344 IWTHLLRNFE 315 L FE Sbjct: 464 AVALTLLRFE 473
>CP3A2_RAT (P05183) Cytochrome P450 3A2 (EC 1.14.14.1) (CYPIIIA2) (P450-PCN2)| (P450/6-beta-A) (Testosterone 6-beta-hydroxylase) Length = 504 Score = 61.6 bits (148), Expect = 2e-09 Identities = 41/128 (32%), Positives = 64/128 (50%), Gaps = 1/128 (0%) Frame = -2 Query: 689 HDILAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFA 510 +DI+ EM+ L + E LRL+P L R D + IPKG +V T P +A Sbjct: 348 YDIVMEMEYLDMVLNETLRLYPIGNRLERVCKKDIELDG-----LFIPKGSVV-TIPTYA 401 Query: 509 -NRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTH 333 + P + P+ + P+RF+ +E + Y+ FG G C+G FA + +K T Sbjct: 402 LHHDPQHWPKPEEFHPERFS--KENKGSIDPYVYLPFGNGPRNCIGMRFALMNMKLALTK 459 Query: 332 LLRNFEFE 309 +L+NF F+ Sbjct: 460 VLQNFSFQ 467
>CP6D3_MUSDO (Q964Q7) Cytochrome P450 6d3 (EC 1.14.-.-) (CYPVID3) (Pyrethroid| resistance cytochrome P450) Length = 520 Score = 61.6 bits (148), Expect = 2e-09 Identities = 46/147 (31%), Positives = 65/147 (44%), Gaps = 4/147 (2%) Frame = -2 Query: 710 RHGDKID----HDILAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPK 543 +HG K D ++ + +M L C+KE R +P L L RQ DF V +F I K Sbjct: 354 KHGIKPDGRITYEAIQDMKYLDLCVKETTRKYPGLPFLNRQCTQDFKV---PNSKFTIKK 410 Query: 542 GHIVATSPAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFA 363 V S +R F P +Y P+RFA +E K A +Y+ FG G C+ + Sbjct: 411 DTNVIISLLGLHRDAKYFPEPLAYKPERFA---DETKDYDAAAYMPFGEGPRHCIAQRMG 467 Query: 362 YLQIKAIWTHLLRNFEFELVSPFPEND 282 + K +L NF E P P + Sbjct: 468 VMNTKVALAKILANFNIE---PMPHKE 491
>CP11A_BOVIN (P00189) Cytochrome P450 11A1, mitochondrial precursor (EC| 1.14.15.6) (CYPXIA1) (P450(scc)) (Cholesterol side-chain cleavage enzyme) (Cholesterol desmolase) Length = 520 Score = 61.6 bits (148), Expect = 2e-09 Identities = 40/126 (31%), Positives = 62/126 (49%) Frame = -2 Query: 683 ILAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFANR 504 +L + +L IKE LRLHP + L R SD + +++ IP +V + R Sbjct: 369 MLQMVPLLKASIKETLRLHPISVTLQRYPESDLVL-----QDYLIPAKTLVQVAIYAMGR 423 Query: 503 LPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLR 324 P F +PD +DP R+ + +DK F + FG G C+G A L++ H+L Sbjct: 424 DPAFFSSPDKFDPTRWLS---KDKDLIHFRNLGFGWGVRQCVGRRIAELEMTLFLIHILE 480 Query: 323 NFEFEL 306 NF+ E+ Sbjct: 481 NFKVEM 486
>C84A1_ARATH (Q42600) Cytochrome P450 84A1 (EC 1.14.-.-)| (Ferulate-5-hydroxylase) (F5H) Length = 520 Score = 61.6 bits (148), Expect = 2e-09 Identities = 37/131 (28%), Positives = 60/131 (45%) Frame = -2 Query: 698 KIDHDILAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSP 519 +++ + ++ L +KE LR+HPP+ +LL ++ D S+ F IPK V + Sbjct: 358 RVEESDIEKLTYLKCTLKETLRMHPPIPLLLHETAEDTSIDG-----FFIPKKSRVMINA 412 Query: 518 AFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIW 339 R P + +PD++ P RF D F +I FG GR C G + Sbjct: 413 FAIGRDPTSWTDPDTFRPSRFLEPGVPDFKGSNFEFIPFGSGRRSCPGMQLGLYALDLAV 472 Query: 338 THLLRNFEFEL 306 H+L F ++L Sbjct: 473 AHILHCFTWKL 483
>C71A4_SOLME (P37117) Cytochrome P450 71A4 (EC 1.14.-.-) (CYPLXXIA4) (P-450EG2)| Length = 507 Score = 61.2 bits (147), Expect = 3e-09 Identities = 46/137 (33%), Positives = 63/137 (45%), Gaps = 6/137 (4%) Frame = -2 Query: 698 KIDHDILAEMDVLYRCIKEALRLHPPLIMLL-RQSHSDFSVTTREGKEFDIPKGHIVATS 522 +I D L M L IKE+LRLHPP +L+ R+S D + + HI A + Sbjct: 347 EITEDDLKNMQYLRAVIKESLRLHPPNSLLVPRESMEDVKL---------LGYYHIPART 397 Query: 521 PAFAN-----RLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYL 357 A N R P ++NP+ + P+RF + D F + FG GR GC G FA Sbjct: 398 QALINVWAIGRDPLSWENPEEFCPERFL-NNDIDMKGLKFELLPFGSGRRGCPGSSFAIA 456 Query: 356 QIKAIWTHLLRNFEFEL 306 I+ L+ F F L Sbjct: 457 VIELALARLVHKFNFAL 473
>C4D14_DROME (O46051) Probable cytochrome P450 4d14 (EC 1.14.-.-) (CYPIVD14)| Length = 507 Score = 61.2 bits (147), Expect = 3e-09 Identities = 41/123 (33%), Positives = 64/123 (52%) Frame = -2 Query: 683 ILAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFANR 504 +L E+ L IKE+LRL P + ++ R D T +GK IP V A R Sbjct: 361 LLGELKYLECVIKESLRLFPSVPIIGRYISQD---TVLDGKL--IPADSNVIILIYHAQR 415 Query: 503 LPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLR 324 P F +P+ + PDRF+ R+ + F+Y F G C+G+ FA L++K+ + ++R Sbjct: 416 DPDYFPDPEKFIPDRFSMERKGE--ISPFAYTPFSAGPRNCIGQKFAMLEMKSTISKMVR 473 Query: 323 NFE 315 +FE Sbjct: 474 HFE 476
>CP4C1_BLADI (P29981) Cytochrome P450 4C1 (EC 1.14.14.1) (CYPIVC1)| Length = 511 Score = 61.2 bits (147), Expect = 3e-09 Identities = 36/122 (29%), Positives = 63/122 (51%) Frame = -2 Query: 680 LAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFANRL 501 LA+M L R IKE+LRL P + + R D + ++ +P G ++ +R Sbjct: 360 LADMKYLERVIKESLRLFPSVPFIGRVLKEDTKIG-----DYLVPAGCMMNLQIYHVHRN 414 Query: 500 PHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRN 321 + NP++++PD F R + ++Y+ F G C+G+ FA L+ K + + +LRN Sbjct: 415 QDQYPNPEAFNPDNFLPERVAKR--HPYAYVPFSAGPRNCIGQKFATLEEKTVLSSILRN 472 Query: 320 FE 315 F+ Sbjct: 473 FK 474
>C71BO_ARATH (Q9LTL8) Cytochrome P450 71B24 (EC 1.14.-.-)| Length = 498 Score = 61.2 bits (147), Expect = 3e-09 Identities = 43/144 (29%), Positives = 72/144 (50%), Gaps = 1/144 (0%) Frame = -2 Query: 710 RHGDKIDHDILAEMDVLYRCIKEALRLHPPLIMLL-RQSHSDFSVTTREGKEFDIPKGHI 534 + +KI+ D + ++ L +KE LRLHP +LL R++ S + + ++IP I Sbjct: 338 KQNEKIEEDDVDKLQYLKLVVKETLRLHPAAPLLLPRETMSQIKI-----QGYNIPSKTI 392 Query: 533 VATSPAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQ 354 + + R P +KNP+ ++P+RF D +F + FG GR C G FA Sbjct: 393 LLVNVWSIGRDPKHWKNPEEFNPERF-IDCPIDYKGNSFEMLPFGSGRRICPGIAFAIAT 451 Query: 353 IKAIWTHLLRNFEFELVSPFPEND 282 ++ +LL +F++ L PE D Sbjct: 452 VELGLLNLLYHFDWRL----PEED 471
>CP4E3_DROME (Q9VL92) Cytochrome P450 4e3 (EC 1.14.-.-) (CYPIVE3)| Length = 526 Score = 61.2 bits (147), Expect = 3e-09 Identities = 38/122 (31%), Positives = 63/122 (51%) Frame = -2 Query: 680 LAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFANRL 501 +A+M L IKEA R++P + + R D+ + +PKG + + Sbjct: 354 IAKMKYLDLFIKEAQRVYPSVPFIGRYCDKDYDINGSI-----VPKGTTLNLALILLGYN 408 Query: 500 PHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRN 321 IFK+P + P+RF EE+K A F Y+ F G C+G+ FA L++K + + ++R+ Sbjct: 409 DRIFKDPHHFRPERF----EEEKPA-PFEYLPFSAGPRNCIGQKFALLELKTVISKVVRS 463 Query: 320 FE 315 FE Sbjct: 464 FE 465
>CP11A_PIG (P10612) Cytochrome P450 11A1, mitochondrial precursor (EC| 1.14.15.6) (CYPXIA1) (P450(scc)) (Cholesterol side-chain cleavage enzyme) (Cholesterol desmolase) Length = 520 Score = 61.2 bits (147), Expect = 3e-09 Identities = 41/126 (32%), Positives = 62/126 (49%) Frame = -2 Query: 683 ILAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFANR 504 +L + +L IKE LRLHP + L R +D + +++ IP +V + R Sbjct: 369 MLQLVPLLKASIKETLRLHPISVTLQRYLVNDLVL-----RDYMIPAKTLVQVAVYAMGR 423 Query: 503 LPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLR 324 P F NP +DP R+ G+E D + F + FG G C+G A L++ H+L Sbjct: 424 DPAFFSNPGQFDPTRWL-GKERDLIH--FRNLGFGWGVRQCVGRRIAELEMTLFLIHILE 480 Query: 323 NFEFEL 306 NF+ EL Sbjct: 481 NFKVEL 486
>THAS_MOUSE (P36423) Thromboxane-A synthase (EC 5.3.99.5) (TXA synthase) (TXS)| (TS) Length = 533 Score = 61.2 bits (147), Expect = 3e-09 Identities = 37/127 (29%), Positives = 57/127 (44%) Frame = -2 Query: 689 HDILAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFA 510 H + + L I E LR++PP R++ D V + IP G ++ + Sbjct: 384 HSLQEGLPYLDMVISETLRMYPPAFRFTREAAQDCEVLGQR-----IPAGTVLEIAVGAL 438 Query: 509 NRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHL 330 + P + NP+++DP+RF A E F+Y+ FG G CLG L +K + Sbjct: 439 HHDPEHWPNPETFDPERFTA--EARLQRRPFTYLPFGAGPRSCLGVRLGLLVVKLTILQV 496 Query: 329 LRNFEFE 309 L F FE Sbjct: 497 LHKFRFE 503
>C71A2_SOLME (P37118) Cytochrome P450 71A2 (EC 1.14.-.-) (CYPLXXIA2) (P-450EG4)| Length = 505 Score = 61.2 bits (147), Expect = 3e-09 Identities = 47/138 (34%), Positives = 63/138 (45%), Gaps = 7/138 (5%) Frame = -2 Query: 698 KIDHDILAEMDVLYRCIKEALRLHPPLIMLL--RQSHSDFSVTTREGKEFDIPKGHIVAT 525 +I D L M L IKE+LRLHP LL R+S D ++ + HI A Sbjct: 346 EITEDDLKNMQYLRAVIKESLRLHPTQESLLVPRESMEDVNL---------LGYYHIPAR 396 Query: 524 SPAFAN-----RLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAY 360 + A N R P ++NP+ Y P+RF + D F + FG GR GC G FA Sbjct: 397 TQAIINAWAIGRDPLSWENPEEYQPERFL-NSDADVKGLNFKLLPFGAGRRGCPGSSFAI 455 Query: 359 LQIKAIWTHLLRNFEFEL 306 I+ L+ F+F L Sbjct: 456 AVIELALARLVHKFDFAL 473
>CP6B3_PAPPO (Q27756) Cytochrome P450 6B3 (EC 1.14.14.1) (CYPVIB4)| (CYP6B3V1/CYP6B3V2) Length = 498 Score = 60.5 bits (145), Expect = 5e-09 Identities = 50/170 (29%), Positives = 69/170 (40%), Gaps = 8/170 (4%) Frame = -2 Query: 710 RHGDKIDHDILAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIV 531 RH I ++ L EM L R E LR +P R + +D+ G + I KG + Sbjct: 339 RHDGNITYECLGEMTFLGRVFDETLRKYPVGDFTQRNAKTDYVFP---GTDITIKKGQTI 395 Query: 530 ATSPAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQI 351 S P + NP+ +DP+RF E K +Y+ F G CLG FA QI Sbjct: 396 IVSTWGIQNDPKYYPNPEKFDPERF--NPENIKNRHPCAYLPFSAGPRNCLGLRFAKWQI 453 Query: 350 KAIWTHLLRNFEFELVSPFPEN--------DWNAMVVGIKGEVMVNYKRR 225 + +L + E P N D + V KG + VN RR Sbjct: 454 EVCVVKVLSKYRVE-----PSNKSSGEFKFDPMRLFVLPKGGIFVNIVRR 498
>CP3AP_MOUSE (O09158) Cytochrome P450 3A25 (EC 1.14.14.1) (CYPIIIA25)| Length = 503 Score = 60.5 bits (145), Expect = 5e-09 Identities = 39/126 (30%), Positives = 60/126 (47%) Frame = -2 Query: 695 IDHDILAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPA 516 + +D L +M+ L + E+LRL+P I L R S D + IPKG +V Sbjct: 345 VTYDALMDMEYLDMVVNESLRLYPIAIRLERVSKKDVEING-----VFIPKGTVVMIPIY 399 Query: 515 FANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWT 336 +R P + P + P+RF+ +E + Y+ FG G C+G FA + IK Sbjct: 400 PLHRNPEYWPEPQEFCPERFS--KENKGNIDPYIYMPFGNGPRNCIGMRFALISIKLAVI 457 Query: 335 HLLRNF 318 +L+NF Sbjct: 458 GVLQNF 463
>C11B1_BOVIN (P15150) Cytochrome P450 11B1, mitochondrial precursor (EC| 1.14.15.4) (CYPXIB1) (P450C11) (Steroid 11-beta-hydroxylase) Length = 503 Score = 60.5 bits (145), Expect = 5e-09 Identities = 38/124 (30%), Positives = 61/124 (49%) Frame = -2 Query: 680 LAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFANRL 501 + E+ +L +KE LRL+P I L R+ SD + + + IP G +V R Sbjct: 359 ITELPLLRAALKETLRLYPVGITLEREVSSDLVL-----QNYHIPAGTLVKVLLYSLGRN 413 Query: 500 PHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRN 321 P +F P+SY P R+ + F +++FG G CLG A +++ + H+L+N Sbjct: 414 PAVFARPESYHPQRWL---DRQGSGSRFPHLAFGFGVRQCLGRRVAEVEMLLLLHHVLKN 470 Query: 320 FEFE 309 F E Sbjct: 471 FLVE 474
>THAS_RAT (P49430) Thromboxane-A synthase (EC 5.3.99.5) (TXA synthase) (TXS)| Length = 533 Score = 60.1 bits (144), Expect = 7e-09 Identities = 35/115 (30%), Positives = 55/115 (47%), Gaps = 1/115 (0%) Frame = -2 Query: 650 IKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFANRLPHIFKNPDSY 471 + E LR++PP R++ D V + IP G ++ + + P + NP+++ Sbjct: 397 VAETLRMYPPAFRFTREAAQDCEVLGQH-----IPAGSVLEIAVGALHHDPEHWPNPETF 451 Query: 470 DPDRFAA-GREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFE 309 DP+RF A R + K F+Y+ FG G CLG L +K +L F FE Sbjct: 452 DPERFTAEARLQQK---PFTYLPFGAGPRSCLGVRLGLLVVKLTLLQVLHKFRFE 503
>THAS_HUMAN (P24557) Thromboxane-A synthase (EC 5.3.99.5) (TXA synthase) (TXS)| Length = 533 Score = 60.1 bits (144), Expect = 7e-09 Identities = 33/114 (28%), Positives = 56/114 (49%) Frame = -2 Query: 650 IKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFANRLPHIFKNPDSY 471 I E LR++PP R++ D V + IP G ++ + + P + +P+++ Sbjct: 397 IAETLRMYPPAFRFTREAAQDCEVLGQR-----IPAGAVLEMAVGALHHDPEHWPSPETF 451 Query: 470 DPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFE 309 +P+RF A E + F+Y+ FG G CLG L++K H+L F F+ Sbjct: 452 NPERFTA--EARQQHRPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHVLHKFRFQ 503
>CP6D5_DROME (Q9VFP1) Probable cytochrome P450 6d5 (EC 1.14.-.-) (CYPVID5)| Length = 508 Score = 59.7 bits (143), Expect = 9e-09 Identities = 39/135 (28%), Positives = 63/135 (46%) Frame = -2 Query: 710 RHGDKIDHDILAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIV 531 +HG K+ +D +++M L CI E R +P L +L R D+ V + I KG + Sbjct: 350 KHGGKLTYDAISDMKYLEACILETARKYPALPLLNRICTKDYPV---PDSKLVIQKGTPI 406 Query: 530 ATSPAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQI 351 S +R F +P +Y P+R+ E K +Y+ FG G C+G + + Sbjct: 407 IISLIGMHRDEEYFPDPLAYKPERYL---ENGKDYTQAAYLPFGEGPRMCIGARMGKVNV 463 Query: 350 KAIWTHLLRNFEFEL 306 K +L NF+ E+ Sbjct: 464 KIAIAKVLSNFDLEI 478
>C98A3_ARATH (O22203) Cytochrome P450 98A3 (EC 1.14.-.-)| Length = 508 Score = 59.7 bits (143), Expect = 9e-09 Identities = 37/112 (33%), Positives = 57/112 (50%), Gaps = 1/112 (0%) Frame = -2 Query: 650 IKEALRLHPPL-IMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFANRLPHIFKNPDS 474 +KE+ RLHPP +ML +S++D + +DIPKG V + R P ++KNP Sbjct: 354 VKESFRLHPPTPLMLPHRSNADVKIGG-----YDIPKGSNVHVNVWAVARDPAVWKNPFE 408 Query: 473 YDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNF 318 + P+RF + D F + FG GR C G + ++ +HLL +F Sbjct: 409 FRPERFLE-EDVDMKGHDFRLLPFGAGRRVCPGAQLGINLVTSMMSHLLHHF 459
>CP6A1_MUSDO (P13527) Cytochrome P450 6A1 (EC 1.14.14.1) (CYPVIA1)| Length = 509 Score = 59.7 bits (143), Expect = 9e-09 Identities = 38/136 (27%), Positives = 68/136 (50%), Gaps = 2/136 (1%) Frame = -2 Query: 701 DKIDHDILAEMDVLYRCIKEALRLHPPLI--MLLRQSHSDFSVTTREGKEFDIPKGHIVA 528 D I +D L + L + + E LR +P + L RQ+ +D+ V ++ +PKG +V Sbjct: 345 DNISYDALMNIPYLDQVLNETLRKYPVGVGSALTRQTLNDYVVP--HNPKYVLPKGTLVF 402 Query: 527 TSPAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIK 348 + P ++ NP+ +DP+RF+ E K + ++ FG G C+G F +Q + Sbjct: 403 IPVLGIHYDPELYPNPEEFDPERFSP--EMVKQRDSVDWLGFGDGPRNCIGMRFGKMQSR 460 Query: 347 AIWTHLLRNFEFELVS 300 ++R+F F + S Sbjct: 461 LGLALVIRHFRFTVCS 476
>CP3A1_RAT (P04800) Cytochrome P450 3A1 (EC 1.14.14.1) (CYPIIIA1) (P450-PCN1)| Length = 504 Score = 59.7 bits (143), Expect = 9e-09 Identities = 37/127 (29%), Positives = 60/127 (47%) Frame = -2 Query: 689 HDILAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFA 510 +D + EM+ L + E LRL+P L R D + +PKG +V Sbjct: 348 YDTVMEMEYLDMVLNETLRLYPIGNRLERVCKKDVEING-----VFMPKGSVVMIPSYAL 402 Query: 509 NRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHL 330 +R P + P+ + P+RF+ +E + Y+ FG G C+G FA + +K T + Sbjct: 403 HRDPQHWPEPEEFRPERFS--KENKGSIDPYVYLPFGNGPRNCIGMRFALMNMKLALTKV 460 Query: 329 LRNFEFE 309 L+NF F+ Sbjct: 461 LQNFSFQ 467
>CP11A_HORSE (O46515) Cytochrome P450 11A1, mitochondrial precursor (EC| 1.14.15.6) (CYPXIA1) (P450(scc)) (Cholesterol side-chain cleavage enzyme) (Cholesterol desmolase) Length = 520 Score = 59.7 bits (143), Expect = 9e-09 Identities = 38/120 (31%), Positives = 57/120 (47%) Frame = -2 Query: 665 VLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFANRLPHIFK 486 +L IKE LRLHP + L R +D + +++ IP +V S + P F Sbjct: 375 LLKASIKETLRLHPIAVTLQRYPQNDLVI-----RDYMIPAKTLVQVSIYTMGQDPTFFS 429 Query: 485 NPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFEL 306 NP +DP R+ +++K F + FG G CLG A L++ H+L NF E+ Sbjct: 430 NPRRFDPTRWL---DKNKDLTHFRNLGFGWGVRQCLGRRIAELEMTLFLIHILENFRVEI 486
>CP3AC_CANFA (P24463) Cytochrome P450 3A12 (EC 1.14.14.1) (CYPIIIA12)| (P450-PBD-1) Length = 503 Score = 59.7 bits (143), Expect = 9e-09 Identities = 36/127 (28%), Positives = 61/127 (48%) Frame = -2 Query: 689 HDILAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFA 510 +D L +M+ L + E LRL+P L R D ++ IPKG +V Sbjct: 347 YDALVQMEYLDMVLNETLRLYPIAGRLERVCKKDVEISG-----VFIPKGTVVMVPTFTL 401 Query: 509 NRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHL 330 +R ++ P+ + P+RF+ R+ ++Y+ FG G C+G FA + +K + Sbjct: 402 HRDQSLWPEPEEFRPERFS--RKNKDSINPYTYLPFGTGPRNCIGMRFAIMNMKLALVRV 459 Query: 329 LRNFEFE 309 L+NF F+ Sbjct: 460 LQNFSFK 466
>C6A19_DROME (P82711) Probable cytochrome P450 6a19 (EC 1.14.-.-) (CYPVIA19)| Length = 503 Score = 59.7 bits (143), Expect = 9e-09 Identities = 41/161 (25%), Positives = 77/161 (47%), Gaps = 3/161 (1%) Frame = -2 Query: 710 RHGDKIDHDILAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIV 531 R+ K+++D + ++ + + I E+LR HP + L R + + ++ I G V Sbjct: 341 RYNGKLEYDSMQDLFYMEKVINESLRKHPVVAHLARIATKPYQ---HSNPKYFIEAGTGV 397 Query: 530 ATSPAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQI 351 S + P + P+ + P+RF E+ K +++ FG G C+G F +Q+ Sbjct: 398 LVSTLGIHHDPEFYPEPEKFIPERF--DEEQVKKRPTCAFLPFGAGPRNCIGLRFGRMQV 455 Query: 350 KAIWTHLLRNFEFEL--VSPFP-ENDWNAMVVGIKGEVMVN 237 L+ NF FEL +P P + N +++G +G + +N Sbjct: 456 IIGLALLIHNFRFELHPKTPVPMKYTINNLLLGSEGGIHLN 496
>CP39A_HUMAN (Q9NYL5) Cytochrome P450 39A1 (EC 1.14.13.99)| (24-hydroxycholesterol 7-alpha-hydroxylase) (Oxysterol 7-alpha-hydroxylase) (hCYP39A1) Length = 469 Score = 59.3 bits (142), Expect = 1e-08 Identities = 40/161 (24%), Positives = 79/161 (49%), Gaps = 3/161 (1%) Frame = -2 Query: 698 KIDHDILAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSP 519 K+ D L ++ ++ C+ E +RL P ++ + V E + IP G ++ SP Sbjct: 316 KVSEDDLEKLLLIKWCVLETIRLKAPGVITRKV------VKPVEILNYIIPSGDLLMLSP 369 Query: 518 AFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIW 339 + +R P F P+ + P+R+ E K + +++FG G+ C FA L+++ Sbjct: 370 FWLHRNPKYFPEPELFKPERWKKANLE-KHSFLDCFMAFGSGKFQCPARWFALLEVQMCI 428 Query: 338 THLLRNFEFELVSPFPENDWNAMVVGI---KGEVMVNYKRR 225 +L ++ L+ P P+ + +VG+ +G+ + YK+R Sbjct: 429 ILILYKYDCSLLDPLPKQSY-LHLVGVPQPEGQCRIEYKQR 468
>CP3AS_BOVIN (P79102) Cytochrome P450 3A28 (EC 1.14.14.1) (CYPIIIA28)| Length = 507 Score = 59.3 bits (142), Expect = 1e-08 Identities = 36/127 (28%), Positives = 57/127 (44%) Frame = -2 Query: 689 HDILAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFA 510 +D L +M+ L + E LR+ P L R D + IPKG V Sbjct: 347 YDALVQMEYLDMVVNETLRMFPIAGRLERVCKKDVEI-----HGVTIPKGTTVLVPLFVL 401 Query: 509 NRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHL 330 + P ++ P+ + P+RF+ ++ + Y+ FG G CLG FA + IK + Sbjct: 402 HNNPELWPEPEEFRPERFSKNNKDS--INPYVYLPFGTGPRNCLGMRFAIMNIKLALVRI 459 Query: 329 LRNFEFE 309 L+NF F+ Sbjct: 460 LQNFSFK 466
>C80A1_BERST (P47195) Berbamunine synthase (EC 1.14.21.3) (Cytochrome P450 80)| (CYPLXXX) ((S)-N-methylcoclaurine oxidase [C-O phenol-coupling]) Length = 487 Score = 59.3 bits (142), Expect = 1e-08 Identities = 39/129 (30%), Positives = 60/129 (46%) Frame = -2 Query: 677 AEMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFANRLP 498 +E+ L C+KE +RL+PP+ +++ + T + + IPKG V + R P Sbjct: 336 SELPYLQACVKETMRLYPPISIMIPHR----CMETCQVMGYTIPKGMDVHVNAHAIGRDP 391 Query: 497 HIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNF 318 +K+P + P+RF E F +I FG GR C G P A I + L+ F Sbjct: 392 KDWKDPLKFQPERFLDSDIEYN-GKQFQFIPFGSGRRICPGRPLAVRIIPLVLASLVHAF 450 Query: 317 EFELVSPFP 291 +EL P Sbjct: 451 GWELPDGVP 459
>C76C4_ARATH (O64635) Cytochrome P450 76C4 (EC 1.14.-.-)| Length = 511 Score = 59.3 bits (142), Expect = 1e-08 Identities = 38/126 (30%), Positives = 63/126 (50%), Gaps = 1/126 (0%) Frame = -2 Query: 680 LAEMDVLYRCIKEALRLHPPLIMLL-RQSHSDFSVTTREGKEFDIPKGHIVATSPAFANR 504 ++ + L +KE RLHP +L+ R++ SD V F +PK V + R Sbjct: 356 ISGLPYLQAVVKETFRLHPAAPLLVPRKAESDVEVLG-----FMVPKDTQVLVNVWAIGR 410 Query: 503 LPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLR 324 P +++NP ++P+RF G++ D + FGGGR C G P A + + LL Sbjct: 411 DPSVWENPSQFEPERFM-GKDIDVKGRDYELTPFGGGRRICPGLPLAVKTVSLMLASLLY 469 Query: 323 NFEFEL 306 +F+++L Sbjct: 470 SFDWKL 475
>CP6B1_PAPPO (Q04552) Cytochrome P450 6B1 (EC 1.14.14.1) (CYPVIB1)| (CYP6B1V1/CYP6B1V2/ CYP6B1V3) Length = 498 Score = 59.3 bits (142), Expect = 1e-08 Identities = 46/166 (27%), Positives = 69/166 (41%), Gaps = 4/166 (2%) Frame = -2 Query: 710 RHGDKIDHDILAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIV 531 RH I ++ L+EM L + E LR +P R + +D+ G + I KG + Sbjct: 339 RHDGNITYECLSEMTYLSKVFDETLRKYPVADFTQRNAKTDYVFP---GTDITIKKGQTI 395 Query: 530 ATSPAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQI 351 S P + NP+ +DP+RF +D+ A Y+ F G CLG FA Q Sbjct: 396 IVSTWGIQNDPKYYPNPEKFDPERFNPENVKDRHPCA--YLPFSAGPRNCLGMRFAKWQS 453 Query: 350 KAIWTHLLRNFEFE----LVSPFPENDWNAMVVGIKGEVMVNYKRR 225 + +L + E PF + + KG + VN RR Sbjct: 454 EVCIMKVLSKYRVEPSMKSSGPFKFDPMRLFALP-KGGIYVNLVRR 498
>CP6T1_DROME (Q9VRI9) Probable cytochrome P450 6t1 (EC 1.14.-.-) (CYPVIT1)| Length = 529 Score = 59.3 bits (142), Expect = 1e-08 Identities = 39/130 (30%), Positives = 64/130 (49%), Gaps = 3/130 (2%) Frame = -2 Query: 686 DILAEMDVLYRCIKEALRLHPPLIMLLR--QSHSDFSVTT-REGKEFDIPKGHIVATSPA 516 D + + L + + E LRL+PP L R S + + ++ G F + G V S Sbjct: 370 DTVTGLVYLRQVVDEVLRLYPPTAFLDRCCNSRTGYDLSPWNGGSPFKLRAGTPVYISVL 429 Query: 515 FANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWT 336 +R + NP+ +DP+RF+A E+ + +Y+ FG G GC+G L+IK Sbjct: 430 GIHRDAQYWPNPEVFDPERFSA--EQRQQHHPMTYLPFGAGPRGCIGTLLGQLEIKVGLL 487 Query: 335 HLLRNFEFEL 306 H+L +F E+ Sbjct: 488 HILNHFRVEV 497
>CP3AB_MOUSE (Q64459) Cytochrome P450 3A11 (EC 1.14.14.1) (CYPIIIA11)| (P-450IIIAM1) (P-450UT) Length = 504 Score = 59.3 bits (142), Expect = 1e-08 Identities = 37/127 (29%), Positives = 58/127 (45%) Frame = -2 Query: 689 HDILAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFA 510 +D + EM+ L + E LRL+P L R D + IPKG V Sbjct: 348 YDTVMEMEYLDMVLNETLRLYPIANRLERVCKKDVELNG-----VYIPKGSTVMIPSYAL 402 Query: 509 NRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHL 330 + P + P+ + P+RF+ +E + Y+ FG G CLG FA + +K T + Sbjct: 403 HHDPQHWSEPEEFQPERFS--KENKGSIDPYVYLPFGNGPRNCLGMRFALMNMKLALTKI 460 Query: 329 LRNFEFE 309 ++NF F+ Sbjct: 461 MQNFSFQ 467
>CP6D1_MUSDO (Q27698) Cytochrome P450 6d1 (EC 1.14.-.-) (CYPVID1) (Pyrethroid| resistance cytochrome P450) (Cytochrome P450 Ipr) Length = 516 Score = 58.9 bits (141), Expect = 1e-08 Identities = 42/147 (28%), Positives = 64/147 (43%), Gaps = 4/147 (2%) Frame = -2 Query: 710 RHGDK----IDHDILAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPK 543 RHG K + ++ + +M L C+ E R +P L L R+ DF V + IPK Sbjct: 354 RHGLKPQGRLTYEAIQDMKYLDLCVMETTRKYPGLPFLNRKCTQDFQVPDTK---LTIPK 410 Query: 542 GHIVATSPAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFA 363 + S +R P F P+ Y P+RFA +E K +Y+ FG G C+ + Sbjct: 411 ETGIIISLLGIHRDPQYFPQPEDYRPERFA---DESKDYDPAAYMPFGEGPRHCIAQRMG 467 Query: 362 YLQIKAIWTHLLRNFEFELVSPFPEND 282 + K +L NF + P P + Sbjct: 468 VMNSKVALAKILANFN---IQPMPRQE 491
>CP310_DROME (Q9VJ71) Probable cytochrome P450 310a1 (EC 1.14.-.-) (CYPCCCXA1)| Length = 492 Score = 58.9 bits (141), Expect = 1e-08 Identities = 48/154 (31%), Positives = 68/154 (44%), Gaps = 9/154 (5%) Frame = -2 Query: 653 CIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFANRLPHIFKNPDS 474 C+KE LR +PPL ++ R +S+ +F I +G + +R F P Sbjct: 337 CLKETLRKYPPLPIIERVCRKSYSLPN---SKFTIDEGKTLMVPLLAMHRDEKYFSEPMK 393 Query: 473 YDPDRFA-----AGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFE 309 Y P RF G+ EDK +I FG G C+G+ FA L IK LL+NF E Sbjct: 394 YKPLRFLQTANDVGQCEDKTKSNV-FIGFGIGGSQCVGQNFAKLVIKVALIKLLQNFHLE 452 Query: 308 L----VSPFPENDWNAMVVGIKGEVMVNYKRRKL 219 L V + A + K + V KRR++ Sbjct: 453 LDANQVKTLKVSHRPAPFIHTKDGLKVKLKRREI 486
>CYPX_BACSU (O34926) Putative cytochrome P450 cypX (EC 1.14.-.-)| Length = 405 Score = 58.9 bits (141), Expect = 1e-08 Identities = 43/130 (33%), Positives = 64/130 (49%), Gaps = 3/130 (2%) Frame = -2 Query: 689 HDILAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFA 510 +D+LA+ ++ R I E LR PP+ ++ RQ D V E I K IV A Sbjct: 257 NDVLADRSLVPRAIAETLRYKPPVQLIPRQLSQDTVVGGME-----IKKDTIVFCMIGAA 311 Query: 509 NRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHL 330 NR P F+ PD ++ R G + +GA +++FG G H C+G FA +I+ + + Sbjct: 312 NRDPEAFEQPDVFNIHREDLG-IKSAFSGAARHLAFGSGIHNCVGAAFAKNEIEIVANIV 370 Query: 329 L---RNFEFE 309 L RN E Sbjct: 371 LDKMRNIRLE 380
>C4D20_DROME (Q9W011) Probable cytochrome P450 4d20 (EC 1.14.-.-) (CYPIVD20)| Length = 510 Score = 58.5 bits (140), Expect = 2e-08 Identities = 34/122 (27%), Positives = 63/122 (51%) Frame = -2 Query: 680 LAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFANRL 501 L ++ L IKE +RL+PP+ + R + + + + IP + +A+R Sbjct: 363 LQDLKYLDCVIKETMRLYPPVPAIGRHAQKELEIGDKT-----IPANTSIYLVLYYAHRD 417 Query: 500 PHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRN 321 + F +P S+ P+RF +E+ F+Y+ F G C+G+ FA L++K + + +LR Sbjct: 418 ANYFPDPLSFRPERFLEDQEQGH--NTFAYVPFSAGPKNCIGQKFAVLEMKVLISKVLRF 475 Query: 320 FE 315 +E Sbjct: 476 YE 477
>CP9C1_DROME (Q9W130) Cytochrome P450 9c1 (EC 1.14.-.-) (CYPIXC1)| Length = 522 Score = 58.5 bits (140), Expect = 2e-08 Identities = 36/134 (26%), Positives = 66/134 (49%), Gaps = 2/134 (1%) Frame = -2 Query: 704 GDK-IDHDILAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGK-EFDIPKGHIV 531 G+K +D+D L M L + E+LR PP ++ R SDF + EG+ ++ + +V Sbjct: 357 GEKPLDYDTLMGMKYLNCVVSESLRKWPPAFIVDRMCGSDFQLKDEEGEVVVNLREDDLV 416 Query: 530 ATSPAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQI 351 + + P F P+ + P+RF E F+Y+ FG G+ C+G A +++ Sbjct: 417 HINVGALHHDPDNFPEPEQFRPERF--DEEHKHEIRQFTYLPFGVGQRSCIGNRLALMEV 474 Query: 350 KAIWTHLLRNFEFE 309 K++ L+ + + Sbjct: 475 KSLIFQLVLRYHLK 488
>C11B1_MESAU (P97720) Cytochrome P450 11B1, mitochondrial precursor (EC| 1.14.15.4) (CYPXIB1) (P450C11) (Steroid 11-beta-hydroxylase) Length = 499 Score = 58.5 bits (140), Expect = 2e-08 Identities = 35/124 (28%), Positives = 63/124 (50%) Frame = -2 Query: 680 LAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFANRL 501 ++++ +L +KE LRL+P + L R SD + + + +P G I+ S R Sbjct: 358 MSDLPLLRAVLKETLRLYPVAVFLERILSSDLVL-----QNYHVPAGTILHMSLYSMGRN 412 Query: 500 PHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRN 321 P +F P+ Y P R+ G+F +++FG G CLG+ A +++ + H+L++ Sbjct: 413 PAVFPRPEHYLPQRWLERN------GSFQHLTFGFGVRQCLGKRLAQVEMLLLLHHVLKS 466 Query: 320 FEFE 309 F E Sbjct: 467 FRVE 470
>CP4X1_HUMAN (Q8N118) Cytochrome P450 4X1 (EC 1.14.14.1) (CYPIVX1)| Length = 509 Score = 58.5 bits (140), Expect = 2e-08 Identities = 42/138 (30%), Positives = 62/138 (44%) Frame = -2 Query: 704 GDKIDHDILAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVAT 525 G I D L EM CIKE RL P + + R D S +P G V Sbjct: 353 GSSITWDQLGEMSYTTMCIKETCRLIPAVPSISR----DLSKPLTFPDGCTLPAGITVVL 408 Query: 524 SPAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKA 345 S + P ++KNP +DP RF+ +E ++Y+ F G C+G+ FA +++K Sbjct: 409 SIWGLHHNPAVWKNPKVFDPLRFS--QENSDQRHPYAYLPFSAGSRNCIGQEFAMIELKV 466 Query: 344 IWTHLLRNFEFELVSPFP 291 +L +F V+P P Sbjct: 467 TIALILLHFR---VTPDP 481
>ERG5_YEAST (P54781) Cytochrome P450 61 (EC 1.14.14.-) (C-22 sterol desaturase)| Length = 538 Score = 58.5 bits (140), Expect = 2e-08 Identities = 38/159 (23%), Positives = 77/159 (48%), Gaps = 1/159 (0%) Frame = -2 Query: 698 KIDHDILAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSP 519 +++ D++ +M IKE LR PP++M+ +F V+ + PKG ++ + Sbjct: 377 ELNLDLIEKMKYTNMVIKETLRYRPPVLMVPYVVKKNFPVSPN----YTAPKGAMLIPTL 432 Query: 518 AFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIW 339 A P +++NPD + P+R+ G + + +++ FG G H CLG+ + + A+ Sbjct: 433 YPALHDPEVYENPDEFIPERWVEGSKASEAKK--NWLVFGCGPHVCLGQTYVMITFAALL 490 Query: 338 THLLRNFEF-ELVSPFPENDWNAMVVGIKGEVMVNYKRR 225 +F V+P E + K ++++ +K+R Sbjct: 491 GKFALYTDFHHTVTPLSEKIKVFATIFPKDDLLLTFKKR 529
>CP6T3_DROME (Q9V676) Probable cytochrome P450 6t3 (EC 1.14.-.-) (CYPVIT3)| Length = 501 Score = 58.5 bits (140), Expect = 2e-08 Identities = 39/131 (29%), Positives = 60/131 (45%), Gaps = 2/131 (1%) Frame = -2 Query: 695 IDHDILAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFS--VTTREGKEFDIPKGHIVATS 522 + +D L + L EALRL+P + R+ S S + + +F +P G S Sbjct: 340 LSYDTLMTLPYLKMVCLEALRLYPAAAFVNRECTSSASEGFSLQPHVDFIVPPGMPAYIS 399 Query: 521 PAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAI 342 +R + P +DP+RF G E + +YI FG G HGC+G LQ+K Sbjct: 400 ILGLHRDERFWPEPCVFDPERF--GPERSRHIHPMTYIPFGAGPHGCIGSRLGVLQLKLG 457 Query: 341 WTHLLRNFEFE 309 H+L+ + E Sbjct: 458 IVHILKQYWVE 468
>CP6W1_DROME (Q9V9L1) Probable cytochrome P450 6w1 (EC 1.14.-.-) (CYPVIW1)| Length = 514 Score = 58.5 bits (140), Expect = 2e-08 Identities = 37/133 (27%), Positives = 60/133 (45%), Gaps = 3/133 (2%) Frame = -2 Query: 701 DKIDHDILAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFS---VTTREGKEFDIPKGHIV 531 D I ++ + EM L + + E LR +P + + R+ T ++P G + Sbjct: 343 DHISYERIQEMPYLSQVVNETLRKYPIVGYIERECSQPAEGERFTLEPFHNMELPHGMSI 402 Query: 530 ATSPAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQI 351 S +R P + +P+ YDP+RF + ++ A Y+ FG G C+G LQ Sbjct: 403 YMSTVAVHRDPQYWPDPEKYDPERFNSSNRDNLNMDA--YMPFGVGPRNCIGMRLGLLQS 460 Query: 350 KAIWTHLLRNFEF 312 K H+LRN F Sbjct: 461 KLGLVHILRNHRF 473
>CP9B2_DROME (Q9V4I1) Cytochrome P450 9b2 (EC 1.14.-.-) (CYPIXB2)| Length = 505 Score = 58.5 bits (140), Expect = 2e-08 Identities = 37/134 (27%), Positives = 66/134 (49%), Gaps = 1/134 (0%) Frame = -2 Query: 707 HGDKIDHDILAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREG-KEFDIPKGHIV 531 +G + +D + +M + I E+LR R D+++T +G K FD G + Sbjct: 342 NGAPLTYDAVQKMTYMDMVISESLRKWTLAAATDRLCSKDYTLTDDDGTKLFDFKVGDRI 401 Query: 530 ATSPAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQI 351 + + F P +DPDRF+ R+ D V ++Y+ FG G C+G +A +Q+ Sbjct: 402 NIPISGLHLDDRYFPEPRKFDPDRFSEERKGDMVP--YTYLPFGVGPRNCIGNRYALMQV 459 Query: 350 KAIWTHLLRNFEFE 309 K + +LL +++ E Sbjct: 460 KGMLFNLLLHYKIE 473
>CP6L1_BLAGE (Q9GQM9) Cytochrome P450 6l1 (EC 1.14.-.-) (CYPVIL1)| Length = 503 Score = 58.5 bits (140), Expect = 2e-08 Identities = 35/133 (26%), Positives = 64/133 (48%) Frame = -2 Query: 707 HGDKIDHDILAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVA 528 HG ++ ++ + +M L + E LR +PP+ + R D+ + G + I KG + Sbjct: 335 HGGQVTYEGVKKMSYLDMVVSEVLRKYPPMSFIDRVCLHDYHIP---GTDVVIEKGTPIF 391 Query: 527 TSPAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIK 348 S +R + +P+ ++P+RF +E+ FSYI FG G C+G + +K Sbjct: 392 VSLLGLHRDSIFYPDPEDFNPERF--NKEKKSGVHPFSYIPFGDGPRNCIGLRLGLMSVK 449 Query: 347 AIWTHLLRNFEFE 309 + LL++ E Sbjct: 450 LVIIMLLQSLRVE 462
>T13H_TAXCU (Q8W4T9) Taxane 13-alpha-hydroxylase (EC 1.14.13.77) (Cytochrome| P450 725A2) Length = 485 Score = 58.2 bits (139), Expect = 2e-08 Identities = 36/129 (27%), Positives = 60/129 (46%) Frame = -2 Query: 704 GDKIDHDILAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVAT 525 G++I L EM ++ ++E LR++PP+ R++ +D + IPKG + Sbjct: 332 GEEIAWKDLKEMKYSWQVVQETLRMYPPIFGTFRKAITDIHYNG-----YTIPKGWKLLW 386 Query: 524 SPAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKA 345 + FK+ D + P RF EE K ++Y+ FGGG C G FA ++ Sbjct: 387 TTYSTQTKEEYFKDADQFKPSRF---EEEGKHVTPYTYLPFGGGMRVCPGWEFAKMETLL 443 Query: 344 IWTHLLRNF 318 H ++ F Sbjct: 444 FLHHFVKAF 452
>C76C3_ARATH (O64638) Cytochrome P450 76C3 (EC 1.14.-.-)| Length = 515 Score = 58.2 bits (139), Expect = 2e-08 Identities = 38/125 (30%), Positives = 59/125 (47%) Frame = -2 Query: 680 LAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFANRL 501 + + L +KE LRLHP ++ R+S SD + F +PK V + R Sbjct: 358 IPSLPYLQAIVKETLRLHPAAPLIPRKSESDVQIMG-----FLVPKNTQVVVNVWAIGRD 412 Query: 500 PHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRN 321 +++NP ++P+RF RE D F I FG GR C G A + + LL + Sbjct: 413 ASVWENPMKFEPERFLL-RETDVKGRDFELIPFGSGRRMCPGISMALKTMHMVLASLLYS 471 Query: 320 FEFEL 306 F+++L Sbjct: 472 FDWKL 476
>CP3AD_MOUSE (Q64464) Cytochrome P450 3A13 (EC 1.14.14.1) (CYPIIIA13)| Length = 503 Score = 58.2 bits (139), Expect = 2e-08 Identities = 35/124 (28%), Positives = 60/124 (48%) Frame = -2 Query: 689 HDILAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFA 510 +D L +M+ L + E LRL+P L R +D + IPKG +V Sbjct: 347 YDTLLQMEYLDMVVNETLRLYPIAGRLERVCKTDVEING-----LFIPKGTVVMIPTFAL 401 Query: 509 NRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHL 330 ++ P + P+ + P+RF+ + +D + + Y+ FG G C+G FA + +K + Sbjct: 402 HKDPKYWPEPEEFRPERFSK-KNQDSI-NPYMYLPFGSGPRNCIGMRFALINMKVALVRV 459 Query: 329 LRNF 318 L+NF Sbjct: 460 LQNF 463
>C76B1_HELTU (O23976) Cytochrome P450 76B1 (EC 1.14.-.-) (7-ethoxycoumarin| O-deethylase) (ECOD) (Phenylurea dealkylase) Length = 490 Score = 57.8 bits (138), Expect = 3e-08 Identities = 41/138 (29%), Positives = 63/138 (45%) Frame = -2 Query: 704 GDKIDHDILAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVAT 525 G + D + + L +KE LRLHPP +LL + VT E + IP G +V Sbjct: 330 GSIVKEDDVLRLPYLSCIVKEVLRLHPPSPLLLPRK----VVTQVELSGYTIPAGTLVFV 385 Query: 524 SPAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKA 345 + R P ++ + + P RF R + + F I FG GR C G P A + Sbjct: 386 NAWAIGRDPTVWDDSLEFKPQRFLESRLDVR-GHDFDLIPFGAGRRICPGIPLATRMVPI 444 Query: 344 IWTHLLRNFEFELVSPFP 291 + LL NF++++ + P Sbjct: 445 MLGSLLNNFDWKIDTKVP 462
>CP4V2_PONPY (Q5RCN6) Cytochrome P450 4V2 (EC 1.14.-.-)| Length = 525 Score = 57.8 bits (138), Expect = 3e-08 Identities = 36/124 (29%), Positives = 58/124 (46%) Frame = -2 Query: 680 LAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFANRL 501 L ++ L IKE LRL P + + R D V + + KG P +R Sbjct: 375 LKKLRYLECVIKETLRLFPSVPLFARSVSEDCEVAG-----YRVLKGTEAVIIPYALHRD 429 Query: 500 PHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRN 321 P F NP+ + P+RF + + ++Y+ F G C+G+ FA ++ K I + +LR+ Sbjct: 430 PRYFPNPEEFQPERFFPENAQGR--HPYAYVPFSAGPRNCIGQKFAVMEEKTILSCILRH 487 Query: 320 FEFE 309 F E Sbjct: 488 FWIE 491
>CP4V2_HUMAN (Q6ZWL3) Cytochrome P450 4V2 (EC 1.14.-.-)| Length = 525 Score = 57.8 bits (138), Expect = 3e-08 Identities = 36/124 (29%), Positives = 58/124 (46%) Frame = -2 Query: 680 LAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFANRL 501 L ++ L IKE LRL P + + R D V + + KG P +R Sbjct: 375 LKKLRYLECVIKETLRLFPSVPLFARSVSEDCEVAG-----YRVLKGTEAVIIPYALHRD 429 Query: 500 PHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRN 321 P F NP+ + P+RF + + ++Y+ F G C+G+ FA ++ K I + +LR+ Sbjct: 430 PRYFPNPEEFQPERFFPENAQGR--HPYAYVPFSAGPRNCIGQKFAVMEEKTILSCILRH 487 Query: 320 FEFE 309 F E Sbjct: 488 FWIE 491
>C71C3_MAIZE (P93703) Cytochrome P450 71C3 (EC 1.14.-.-) (Benzoxazineless 5)| Length = 535 Score = 57.8 bits (138), Expect = 3e-08 Identities = 40/144 (27%), Positives = 69/144 (47%), Gaps = 3/144 (2%) Frame = -2 Query: 701 DKIDHDILAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATS 522 D I D L+ + L +KEALRLHPP +LL +S + + IP V + Sbjct: 370 DMIREDDLSSLPYLKASMKEALRLHPPGPLLLPH----YSTADCQIDGYHIPANPRVLVN 425 Query: 521 PAFANRLPHIFKNPDSYDPDRFAAGR--EEDKVAGA-FSYISFGGGRHGCLGEPFAYLQI 351 R P +++ P+ + P+RF + + +G F Y+ FG GR C G F + Sbjct: 426 GWAIGRDPAVWEKPEEFMPERFMRDGWDKSNSYSGQDFRYLPFGSGRRICPGANFGLATM 485 Query: 350 KAIWTHLLRNFEFELVSPFPENDW 279 + + +L+ +F++E+ + + W Sbjct: 486 EIMLANLMYHFDWEVPNEKEDGCW 509
>CP26A_BRARE (P79739) Cytochrome P450 26A1 (EC 1.14.-.-) (Retinoic| acid-metabolizing cytochrome) (P450RAI) (Retinoic acid 4-hydroxylase) Length = 492 Score = 57.8 bits (138), Expect = 3e-08 Identities = 38/128 (29%), Positives = 63/128 (49%) Frame = -2 Query: 704 GDKIDHDILAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVAT 525 G + ++L ++ IKE LR++PP+ R ++ T E + IPKG V Sbjct: 338 GKGLSMELLDQLKYTGCVIKETLRINPPVPGGFR-----VALKTFELNGYQIPKGWNVIY 392 Query: 524 SPAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKA 345 S + + +F N + + P+RF + ED F+YI FGGG C+G+ FA + +K Sbjct: 393 SICDTHDVADVFPNKEEFQPERFMSKGLED--GSRFNYIPFGGGSRMCVGKEFAKVLLKI 450 Query: 344 IWTHLLRN 321 L ++ Sbjct: 451 FLVELTQH 458
>CP3A5_HUMAN (P20815) Cytochrome P450 3A5 (EC 1.14.14.1) (CYPIIIA5) (P450-PCN3)| (HLp2) Length = 502 Score = 57.8 bits (138), Expect = 3e-08 Identities = 36/127 (28%), Positives = 60/127 (47%) Frame = -2 Query: 689 HDILAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFA 510 +D + +M+ L + E LRL P I L R D + IPKG +V Sbjct: 347 YDAVVQMEYLDMVVNETLRLFPVAIRLERTCKKDVEING-----VFIPKGSMVVIPTYAL 401 Query: 509 NRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHL 330 + P + P+ + P+RF+ +++D + + Y FG G C+G FA + +K + Sbjct: 402 HHDPKYWTEPEEFRPERFS--KKKDSI-DPYIYTPFGTGPRNCIGMRFALMNMKLALIRV 458 Query: 329 LRNFEFE 309 L+NF F+ Sbjct: 459 LQNFSFK 465
>CP11A_RAT (P14137) Cytochrome P450 11A1, mitochondrial precursor (EC| 1.14.15.6) (CYPXIA1) (P450(scc)) (Cholesterol side-chain cleavage enzyme) (Cholesterol desmolase) Length = 526 Score = 57.8 bits (138), Expect = 3e-08 Identities = 38/122 (31%), Positives = 57/122 (46%) Frame = -2 Query: 665 VLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFANRLPHIFK 486 +L IKE LRLHP + L R +D + + + IP +V + R F Sbjct: 373 LLKASIKETLRLHPISVTLQRYIVNDLVL-----RNYKIPAKTLVQVASYAMGRESSFFP 427 Query: 485 NPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFEL 306 NP+ +DP R+ E+ + F Y+ FG G CLG A L++ ++L NF E+ Sbjct: 428 NPNKFDPTRWL---EKSQNTTHFRYLGFGWGVRQCLGRRIAELEMTIFLINVLENFRIEV 484 Query: 305 VS 300 S Sbjct: 485 QS 486
>C78A3_SOYBN (O48927) Cytochrome P450 78A3 (EC 1.14.-.-)| Length = 523 Score = 57.4 bits (137), Expect = 4e-08 Identities = 43/133 (32%), Positives = 65/133 (48%), Gaps = 5/133 (3%) Frame = -2 Query: 695 IDHDILAEMDVLYRCIKEALRLHP--PLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATS 522 + D +A M L +KE LRLHP PL+ R S +D TT +G + +P G + Sbjct: 363 VAEDDVAVMTYLPAVVKEVLRLHPPGPLLSWARLSIND---TTIDG--YHVPAGTTAMVN 417 Query: 521 PAFANRLPHIFKNPDSYDPDRF--AAGREEDKVAGAFSYIS-FGGGRHGCLGEPFAYLQI 351 R PH++K+P + P+RF A G E + G+ ++ FG GR C G+ + + Sbjct: 418 TWAICRDPHVWKDPLEFMPERFVTAGGDAEFSILGSDPRLAPFGSGRRACPGKTLGWATV 477 Query: 350 KAIWTHLLRNFEF 312 LL FE+ Sbjct: 478 NFWVASLLHEFEW 490
>CP3A4_HUMAN (P08684) Cytochrome P450 3A4 (EC 1.14.13.67) (Quinine| 3-monooxygenase) (CYPIIIA4) (Nifedipine oxidase) (Taurochenodeoxycholate 6-alpha-hydroxylase) (EC 1.14.13.97) (NF-25) (P450-PCN1) Length = 502 Score = 57.4 bits (137), Expect = 4e-08 Identities = 35/127 (27%), Positives = 59/127 (46%) Frame = -2 Query: 689 HDILAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFA 510 +D + +M+ L + E LRL P + L R D + IPKG +V Sbjct: 346 YDTVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEING-----MFIPKGWVVMIPSYAL 400 Query: 509 NRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHL 330 +R P + P+ + P+RF+ +++ + Y FG G C+G FA + +K + Sbjct: 401 HRDPKYWTEPEKFLPERFSKKNKDN--IDPYIYTPFGSGPRNCIGMRFALMNMKLALIRV 458 Query: 329 LRNFEFE 309 L+NF F+ Sbjct: 459 LQNFSFK 465
>C71A8_MENPI (Q42716) Cytochrome P450 71A8 (EC 1.14.-.-)| Length = 502 Score = 57.4 bits (137), Expect = 4e-08 Identities = 38/131 (29%), Positives = 63/131 (48%), Gaps = 1/131 (0%) Frame = -2 Query: 695 IDHDILAEMDVLYRCIKEALRLHPPLIMLL-RQSHSDFSVTTREGKEFDIPKGHIVATSP 519 I D + +M L +KE +R H P+ +L+ R + +D V +D+P G +V + Sbjct: 348 ITDDDIEKMHYLKAVMKETMRFHTPIPLLVPRVARNDVEVMG-----YDVPVGTMVMINA 402 Query: 518 AFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIW 339 R P + P+ + P+RF + K F I FG GR GC G F ++ Sbjct: 403 WAIGRDPTSWDEPEKFRPERFLNSSVDFKGLD-FELIPFGAGRRGCPGTTFPMATLEFTL 461 Query: 338 THLLRNFEFEL 306 +L++ F++EL Sbjct: 462 ANLMQKFDWEL 472
>CP3A3_HUMAN (P05184) Cytochrome P450 3A3 (EC 1.14.14.1) (CYPIIIA3) (HLp)| Length = 503 Score = 57.4 bits (137), Expect = 4e-08 Identities = 35/127 (27%), Positives = 59/127 (46%) Frame = -2 Query: 689 HDILAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFA 510 +D + +M+ L + E LRL P + L R D + IPKG +V Sbjct: 347 YDTVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEING-----MFIPKGWVVMIPSYAL 401 Query: 509 NRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHL 330 +R P + P+ + P+RF+ +++ + Y FG G C+G FA + +K + Sbjct: 402 HRDPKYWTEPEKFLPERFSKKNKDN--IDPYIYTPFGSGPRNCIGMRFALMNMKLALIRV 459 Query: 329 LRNFEFE 309 L+NF F+ Sbjct: 460 LQNFSFK 466
>C71B6_ARATH (O65787) Cytochrome P450 71B6 (EC 1.14.-.-)| Length = 503 Score = 57.4 bits (137), Expect = 4e-08 Identities = 43/147 (29%), Positives = 69/147 (46%), Gaps = 3/147 (2%) Frame = -2 Query: 704 GDK--IDHDILAEMDVLYRCIKEALRLHPPL-IMLLRQSHSDFSVTTREGKEFDIPKGHI 534 GDK + +D L + + IKE RLH P I++ R++ ++F + K +DI G Sbjct: 342 GDKGIVTYDDLEALVYMKMVIKETWRLHAPSPILIPREAMTNFKI-----KGYDIYPGTR 396 Query: 533 VATSPAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQ 354 + + R P ++K+PD + P+RF E K +F + FG GR GC P Y+ Sbjct: 397 IHVNAWAIGRNPDVWKDPDEFIPERFVDSNVETK-GTSFELLPFGSGRRGC---PAMYVG 452 Query: 353 IKAIWTHLLRNFEFELVSPFPENDWNA 273 + + E+ L + DW A Sbjct: 453 LSTV--------EYTLANLLYHFDWKA 471
>F3PH_ARATH (Q9SD85) Flavonoid 3'-monooxygenase (EC 1.14.13.21) (Flavonoid| 3'-hydroxylase) (AtF3'H) (Cytochrome P450 75B1) (TRANSPARENT TESTA 7 protein) Length = 513 Score = 57.0 bits (136), Expect = 6e-08 Identities = 40/133 (30%), Positives = 63/133 (47%), Gaps = 3/133 (2%) Frame = -2 Query: 695 IDHDILAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPA 516 ++ +A++ L IKE RLHPP + L S+ + E + IPKG + T+ Sbjct: 342 VNESDIAQLPYLQAVIKENFRLHPPTPLSLPHIASE----SCEINGYHIPKGSTLLTNIW 397 Query: 515 FANRLPHIFKNPDSYDPDRFAAGREE---DKVAGAFSYISFGGGRHGCLGEPFAYLQIKA 345 R P + +P ++ P+RF G E+ D F I FG GR C G I+ Sbjct: 398 AIARDPDQWSDPLAFKPERFLPGGEKSGVDVKGSDFELIPFGAGRRICAGLSLGLRTIQF 457 Query: 344 IWTHLLRNFEFEL 306 + L++ F++EL Sbjct: 458 LTATLVQGFDWEL 470
>CP4X1_RAT (Q8K4D6) Cytochrome P450 4X1 (EC 1.14.14.1) (CYPIVX1)| Length = 507 Score = 57.0 bits (136), Expect = 6e-08 Identities = 43/128 (33%), Positives = 62/128 (48%), Gaps = 1/128 (0%) Frame = -2 Query: 704 GDKIDHDILAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVAT 525 G I + L E+ CIKE LRL PP+ + R+ +T +G +P G V Sbjct: 351 GSSITWEQLDEIPYTTMCIKETLRLIPPIPSISRELSK--PLTLPDG--HSLPAGMTVVL 406 Query: 524 SPAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIK- 348 S + P ++K+P +DP RF E + AF + F G C+G+ FA L++K Sbjct: 407 SIWGLHHNPAVWKDPKVFDPLRFTKENSEQRHPCAF--LPFSSGPRNCIGQQFAMLELKV 464 Query: 347 AIWTHLLR 324 AI LLR Sbjct: 465 AIALTLLR 472
>CP9B1_DROME (Q9V4I0) Cytochrome P450 9b1 (EC 1.14.-.-) (CYPIXB1)| Length = 505 Score = 57.0 bits (136), Expect = 6e-08 Identities = 37/145 (25%), Positives = 66/145 (45%), Gaps = 1/145 (0%) Frame = -2 Query: 704 GDKIDHDILAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREG-KEFDIPKGHIVA 528 G + +D EM + I E+LR R D+++T EG K F+ G + Sbjct: 343 GAPLTYDAAQEMTYMDMVISESLRKWTLSAAADRLCAKDYTLTDDEGTKLFEFKAGDNIN 402 Query: 527 TSPAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIK 348 + F P +DP+RF+ R++D + ++Y+ FG G C+G +A +Q K Sbjct: 403 IPICGLHWDERFFPQPQRFDPERFSERRKKDLIP--YTYLPFGVGPRSCIGNRYAVMQAK 460 Query: 347 AIWTHLLRNFEFELVSPFPENDWNA 273 + +L+ N++ E + W + Sbjct: 461 GMLYNLMLNYKIEASPRTTRDMWES 485
>C11B1_PIG (Q29552) Cytochrome P450 11B1, mitochondrial precursor (EC| 1.14.15.4) (CYPXIB1) (P450C11) (Steroid 11-beta-hydroxylase) Length = 503 Score = 57.0 bits (136), Expect = 6e-08 Identities = 38/125 (30%), Positives = 63/125 (50%), Gaps = 1/125 (0%) Frame = -2 Query: 680 LAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFANRL 501 + E+ +L +KE LRL+P I L R SD + + + IP G +V R Sbjct: 359 ITELPLLRAALKETLRLYPVGIFLDRCVTSDLVL-----QNYHIPAGTLVKVLLYSLGRN 413 Query: 500 PHIFKNPDSYDPDRFAAGREEDKVAGA-FSYISFGGGRHGCLGEPFAYLQIKAIWTHLLR 324 P +F P+ Y P R+ +++ +G F +++FG G CLG A +++ + H+L+ Sbjct: 414 PAVFARPERYHPQRWL----DNQGSGTRFPHLAFGFGMRQCLGRRLAQVEMLLLLHHVLK 469 Query: 323 NFEFE 309 NF E Sbjct: 470 NFLVE 474
>CP4E5_DROMT (O44221) Cytochrome P450 4e5, mitochondrial precursor (EC 1.14.-.-)| (CYPIVE5) Length = 522 Score = 56.6 bits (135), Expect = 7e-08 Identities = 36/134 (26%), Positives = 65/134 (48%), Gaps = 4/134 (2%) Frame = -2 Query: 704 GDKIDHDI----LAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGH 537 G++++ D ++ M L IKEA R++P + + R + D+++ +PKG Sbjct: 342 GNELNRDATFQEISAMKYLDLFIKEAQRVYPSVPFIGRYTDKDYNIHGTI-----MPKGT 396 Query: 536 IVATSPAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYL 357 + +F+ P + P+RF E + G F Y+ F G C+G+ FA L Sbjct: 397 TLNLGIIVLGYDDRVFEEPHRFYPERF-----EKQKPGPFEYVPFSAGPRNCIGQKFALL 451 Query: 356 QIKAIWTHLLRNFE 315 ++K + + L+R FE Sbjct: 452 ELKTVISKLVRTFE 465
>C99A1_SORBI (O48957) Cytochrome P450 CYP99A1 (EC 1.14.-.-) (Fragment)| Length = 519 Score = 56.6 bits (135), Expect = 7e-08 Identities = 39/121 (32%), Positives = 57/121 (47%), Gaps = 6/121 (4%) Frame = -2 Query: 650 IKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFANRLPHIFKNPDSY 471 +KE LRLHP L +LL +S + T + F++ KG V + R P + +P+ + Sbjct: 362 VKEGLRLHPVLPLLLPRSCQE----TCDVGGFEVTKGTKVIVNAWALARSPERWHDPEEF 417 Query: 470 DPDRFA------AGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFE 309 P+RFA A D F YI FG GR C G F ++ + LL F++ Sbjct: 418 RPERFADDDGSSAAVAVDYRGSQFEYIPFGSGRRMCPGNTFGLAALELMVARLLYYFDWS 477 Query: 308 L 306 L Sbjct: 478 L 478
>CP391_DROME (Q9VQD2) Probable cytochrome P450 309a1 (EC 1.14.-.-) (CYPCCCIXA1)| Length = 529 Score = 56.6 bits (135), Expect = 7e-08 Identities = 37/157 (23%), Positives = 65/157 (41%) Frame = -2 Query: 698 KIDHDILAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSP 519 +I +D + + L +C E+LRL P+ +R + + K D+ G V Sbjct: 371 QISYDQINNLPYLDQCFNESLRLTTPIGFFMRICTKPTQINLGDDKTLDLEPGVTVMVPA 430 Query: 518 AFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIW 339 + I+ + PDRF G + ++ FG G CLG L +K Sbjct: 431 YQYHHDNDIYPEASEFRPDRFENGAAS-VLTKRGCFLPFGDGPRICLGMRVGQLSVKTAI 489 Query: 338 THLLRNFEFELVSPFPENDWNAMVVGIKGEVMVNYKR 228 H+L N++ E + P + M + + G+V + Y + Sbjct: 490 VHILSNYQVEQMKKVPLGADSGMGIFLNGDVELKYTK 526
>CP343_HUMAN (Q9HB55) Cytochrome P450 3A43 (EC 1.14.14.1)| Length = 503 Score = 56.6 bits (135), Expect = 7e-08 Identities = 37/129 (28%), Positives = 58/129 (44%) Frame = -2 Query: 695 IDHDILAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPA 516 + +D L +M+ L + E LRL P + + R D + IPKG V Sbjct: 345 VTYDALVQMEYLDMVVNETLRLFPVVSRVTRVCKKDIEING-----VFIPKGLAVMVPIY 399 Query: 515 FANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWT 336 + P + P+ + P+RF+ + +D + + YI FG G C+G FA IK Sbjct: 400 ALHHDPKYWTEPEKFCPERFSK-KNKDSI-DLYRYIPFGAGPRNCIGMRFALTNIKLAVI 457 Query: 335 HLLRNFEFE 309 L+NF F+ Sbjct: 458 RALQNFSFK 466
>CP3AJ_CAPAE (P79152) Cytochrome P450 3A19 (EC 1.14.14.1) (CYPIIIA19) (Fragment)| Length = 218 Score = 56.2 bits (134), Expect = 9e-08 Identities = 35/126 (27%), Positives = 55/126 (43%) Frame = -2 Query: 689 HDILAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFA 510 +D L +M+ L + E LR+ P L R D + IPKG V Sbjct: 58 YDALVQMEYLDMVVNETLRMFPIAGRLERLCKKDVEI-----HGVSIPKGTTVMVPLFVL 112 Query: 509 NRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHL 330 + P + P+ + P+RF+ ++ + Y+ FG G C+G FA + IK + Sbjct: 113 HNNPEFWPEPEEFRPERFSKKNKDG--INPYVYLPFGTGPRNCVGMRFALMNIKLALVRI 170 Query: 329 LRNFEF 312 L+NF F Sbjct: 171 LQNFSF 176
>C340_ORYLA (Q98T91) Cytochrome P450 3A40 (EC 1.14.14.1)| Length = 502 Score = 56.2 bits (134), Expect = 9e-08 Identities = 35/125 (28%), Positives = 61/125 (48%) Frame = -2 Query: 680 LAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFANRL 501 L EM+ L + E+LRL+P L R + + T E IPK +V +R Sbjct: 351 LMEMEYLDCVVNESLRLYPIAARLERVAKA-----TVEVNGLVIPKDMVVMVPTWPLHRD 405 Query: 500 PHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRN 321 P ++ P+ + P+RF+ +E ++Y+ FG G C+G FA + +K +L+ Sbjct: 406 PELWPEPEKFKPERFS--KENKDTFDPYTYMPFGAGPRNCIGMRFALVMMKLAVVEILQT 463 Query: 320 FEFEL 306 ++F + Sbjct: 464 YDFSV 468
>CP11A_HUMAN (P05108) Cytochrome P450 11A1, mitochondrial precursor (EC| 1.14.15.6) (CYPXIA1) (P450(scc)) (Cholesterol side-chain cleavage enzyme) (Cholesterol desmolase) Length = 521 Score = 56.2 bits (134), Expect = 9e-08 Identities = 38/126 (30%), Positives = 62/126 (49%) Frame = -2 Query: 683 ILAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFANR 504 +L + +L IKE LRLHP + L R +D + +++ IP +V + R Sbjct: 370 MLQLVPLLKASIKETLRLHPISVTLQRYLVNDLVL-----RDYMIPAKTLVQVAIYALGR 424 Query: 503 LPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLR 324 P F +P+++DP R+ + +DK F + FG G CLG A L++ ++L Sbjct: 425 EPTFFFDPENFDPTRWLS---KDKNITYFRNLGFGWGVRQCLGRRIAELEMTIFLINMLE 481 Query: 323 NFEFEL 306 NF E+ Sbjct: 482 NFRVEI 487
>CP4Z1_HUMAN (Q86W10) Cytochrome P450 4Z1 (EC 1.14.14.1) (CYPIVZ1)| Length = 505 Score = 56.2 bits (134), Expect = 9e-08 Identities = 38/128 (29%), Positives = 67/128 (52%), Gaps = 1/128 (0%) Frame = -2 Query: 704 GDKIDHDILAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVAT 525 G I + L++M CIKE LRL+ P++ + R D +T +G+ +P G V Sbjct: 351 GSSITWEHLSQMPYTTMCIKECLRLYAPVVNISRL--LDKPITFPDGR--SLPAGITVFI 406 Query: 524 SPAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIK- 348 + + P+ +++P ++P RF+ RE + +++I F G C+G+ FA ++ K Sbjct: 407 NIWALHHNPYFWEDPQVFNPLRFS--RENSEKIHPYAFIPFSAGLRNCIGQHFAIIECKV 464 Query: 347 AIWTHLLR 324 A+ LLR Sbjct: 465 AVALTLLR 472
>C71C1_MAIZE (Q43250) Cytochrome P450 71C1 (EC 1.14.-.-) (Benzoxazineless 4)| Length = 535 Score = 55.8 bits (133), Expect = 1e-07 Identities = 40/136 (29%), Positives = 63/136 (46%), Gaps = 3/136 (2%) Frame = -2 Query: 704 GDKIDHDILAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVAT 525 G + + L+ M L IKE++R+HPP LL FS E + IP G V Sbjct: 364 GRMVMEEDLSRMPYLKATIKESMRIHPPAPFLLPH----FSTHDCEINGYTIPAGTRVIV 419 Query: 524 SPAFANRLPHIFKNPDSYDPDRFAA-GR--EEDKVAGAFSYISFGGGRHGCLGEPFAYLQ 354 + R P + + + P+RF GR E D ++ FG GR C G FA Sbjct: 420 NAWALARDPTCWDKAEEFFPERFLEQGRDAEVDMYGKDIRFVPFGAGRRICAGATFAIAT 479 Query: 353 IKAIWTHLLRNFEFEL 306 ++ + +L+ +F++E+ Sbjct: 480 VEIMLANLIYHFDWEM 495
>CP3AG_MOUSE (Q64481) Cytochrome P450 3A16 (EC 1.14.14.1) (CYPIIIA16)| Length = 504 Score = 55.8 bits (133), Expect = 1e-07 Identities = 35/127 (27%), Positives = 56/127 (44%) Frame = -2 Query: 689 HDILAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFA 510 +D + M+ L + E LRL+P L R D + IPKG V Sbjct: 348 YDTVMAMEYLDMVLNETLRLYPITNRLQRVCKKDVEING-----IYIPKGSTVIIPSYVL 402 Query: 509 NRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHL 330 + P + P+ + P+RF+ +E + Y+ FG G C+G FA + +K + Sbjct: 403 HHDPQHWPEPEEFQPERFS--KENKGSIDPYVYLPFGNGPRNCIGMRFALMNMKLALIKV 460 Query: 329 LRNFEFE 309 L+NF F+ Sbjct: 461 LQNFSFQ 467
>CP11A_MACFA (Q2XV99) Cytochrome P450 11A1, mitochondrial precursor (EC| 1.14.15.6) (CYPXIA1) (P450(scc)) (Cholesterol side-chain cleavage enzyme) (Cholesterol desmolase) Length = 521 Score = 55.8 bits (133), Expect = 1e-07 Identities = 39/126 (30%), Positives = 61/126 (48%) Frame = -2 Query: 683 ILAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFANR 504 IL + +L IKE LRLHP + L R +D + + + IP +V + R Sbjct: 370 ILQLVPLLKASIKETLRLHPISVTLQRYLVNDLVL-----RGYMIPAKTLVQVAIYALGR 424 Query: 503 LPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLR 324 P F +P+++DP R+ + +DK F + FG G CLG A L++ ++L Sbjct: 425 EPTFFFDPENFDPTRWLS---KDKNITYFRNLGFGWGVRQCLGRRIAELEMTIFLINMLE 481 Query: 323 NFEFEL 306 NF E+ Sbjct: 482 NFRVEI 487
>CP3AA_MESAU (Q64148) Cytochrome P450 3A10 (EC 1.14.13.94) (CYPIIIA10)| (Lithocholate 6-beta-hydroxylase) (6 beta-hydroxylase) Length = 503 Score = 55.8 bits (133), Expect = 1e-07 Identities = 38/129 (29%), Positives = 58/129 (44%) Frame = -2 Query: 695 IDHDILAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPA 516 + +D+L M+ L I E LRL+P L R S + IPKG V Sbjct: 345 VTYDVLMGMEYLDMVINEGLRLYPIANRLERISKKAVEING-----LFIPKGITVMVPTY 399 Query: 515 FANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWT 336 +R P + P+ + P+RF+ +E + Y+ FG G C+G FA L +K Sbjct: 400 PLHRDPEYWPEPEEFRPERFS--KENKGSIDPYVYMPFGNGPRNCIGMRFALLSMKLAVV 457 Query: 335 HLLRNFEFE 309 +L+NF + Sbjct: 458 SVLQNFTLQ 466
>CP3A7_HUMAN (P24462) Cytochrome P450 3A7 (EC 1.14.14.1) (CYPIIIA7) (P450-HFLA)| Length = 503 Score = 55.8 bits (133), Expect = 1e-07 Identities = 33/127 (25%), Positives = 59/127 (46%) Frame = -2 Query: 689 HDILAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFA 510 +D + +++ L + E LRL P + L R D + IPKG +V Sbjct: 347 YDTVLQLEYLDMVVNETLRLFPVAMRLERVCKKDVEING-----MFIPKGVVVMIPSYVL 401 Query: 509 NRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHL 330 + P ++ P+ + P+RF+ +++ + Y FG G C+G FA + +K + Sbjct: 402 HHDPKYWREPEKFLPERFSKKNKDN--IDPYIYTPFGSGPRNCIGMRFALVNMKLALVRV 459 Query: 329 LRNFEFE 309 L+NF F+ Sbjct: 460 LQNFSFK 466
>C6A18_DROME (Q9VB31) Probable cytochrome P450 6a18 (EC 1.14.-.-) (CYPVIA18)| Length = 507 Score = 55.5 bits (132), Expect = 2e-07 Identities = 40/161 (24%), Positives = 76/161 (47%), Gaps = 4/161 (2%) Frame = -2 Query: 710 RHGDKIDHDILAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIV 531 +H K ++ + ++ L + I E LR + + + R + F V +F I G V Sbjct: 346 QHDQKFTYECIKDLKYLDQVINETLRHYTIVPNVDRVAAKRFVVPGNP--KFVIEAGQSV 403 Query: 530 ATSPAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQI 351 + + P I+ P+ + P+RF+ EE + +++ FG G C+G F +Q Sbjct: 404 IIPSSAIHHDPSIYPEPNEFRPERFSP--EESAKRPSVAWLPFGEGPRNCIGLRFGQMQA 461 Query: 350 KAIWTHLLRNFEFELVSPFPE----NDWNAMVVGIKGEVMV 240 + L++NF F S P+ + +A+++GIKG + + Sbjct: 462 RIGLAMLIKNFTFSPCSATPDPLTFDPHSAILLGIKGGIQL 502
>CP6A9_DROME (Q27594) Cytochrome P450 6a9 (EC 1.14.-.-) (CYPVIA9)| Length = 504 Score = 55.5 bits (132), Expect = 2e-07 Identities = 34/135 (25%), Positives = 69/135 (51%) Frame = -2 Query: 710 RHGDKIDHDILAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIV 531 ++ +I ++ + +M L + I E LRL+ L +L R+ D+ V ++ I KG V Sbjct: 344 KYNGEITYESMKDMVYLDQVISETLRLYTVLPVLNRECLEDYEVPGHP--KYVIKKGMPV 401 Query: 530 ATSPAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQI 351 +R ++ NP++++PD F+ R +++ + ++ FG G C+G F +Q Sbjct: 402 LIPCGAMHRDEKLYANPNTFNPDNFSPERVKER--DSVEWLPFGDGPRNCIGMRFGQMQA 459 Query: 350 KAIWTHLLRNFEFEL 306 ++ L+ F+F + Sbjct: 460 RSGLALLINRFKFSV 474
>CP341_MOUSE (Q9JMA7) Cytochrome P450 3A41 (EC 1.14.14.1)| Length = 504 Score = 55.5 bits (132), Expect = 2e-07 Identities = 36/127 (28%), Positives = 59/127 (46%) Frame = -2 Query: 689 HDILAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFA 510 +D + EM+ L + E LRL+P L R D + IPKG V Sbjct: 348 YDTVMEMEYLDMVLNETLRLYPIGNRLERFCKKDVELNG-----VYIPKGSTVMIPSYAL 402 Query: 509 NRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHL 330 + P + P+ + P+RF+ +E + Y+ FG G C+G FA++ +K T + Sbjct: 403 HHDPQHWPEPEEFQPERFS--KENKGSIDPYLYMPFGIGPRNCIGMRFAFMTMKLALTKV 460 Query: 329 LRNFEFE 309 ++NF F+ Sbjct: 461 MQNFSFQ 467
>CP4P3_DROME (Q9V559) Probable cytochrome P450 4p3 (EC 1.14.-.-) (CYPIVP3)| Length = 515 Score = 55.1 bits (131), Expect = 2e-07 Identities = 41/152 (26%), Positives = 72/152 (47%), Gaps = 9/152 (5%) Frame = -2 Query: 650 IKEALRLHPPLIMLLRQSHSDFSVTTREGKEFD---IPKGHIVATSPAFANRLPHIFKNP 480 IKE +RL P + + R+ TTRE + + +PKG + +R P + +P Sbjct: 378 IKETMRLFPSVPAMGRE-------TTRETELSNGLILPKGSQIFVHVFDIHRNPEYWDSP 430 Query: 479 DSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFELVS 300 + + P+RF +++ ++YI F G+ C+G+ FA ++K + LL+ F+ Sbjct: 431 EEFRPERFLPENSQNR--HTYAYIPFSAGQRNCIGQKFAMQEMKTLMVALLKQFQI---- 484 Query: 299 PFPENDWNAMV------VGIKGEVMVNYKRRK 222 PE D +V + K ++ V RRK Sbjct: 485 -LPEIDPKTIVFQTGLTLRTKNQIHVKLVRRK 515
>CP17A_MESAU (P70687) Cytochrome P450 17A1 (EC 1.14.99.9) (CYPXVII) (P450-C17)| (P450c17) (Steroid 17-alpha-hydroxylase/17,20 lyase) Length = 511 Score = 55.1 bits (131), Expect = 2e-07 Identities = 35/121 (28%), Positives = 58/121 (47%), Gaps = 1/121 (0%) Frame = -2 Query: 665 VLYRCIKEALRLHPPLIMLL-RQSHSDFSVTTREGKEFDIPKGHIVATSPAFANRLPHIF 489 +L I+E LR+ P ML+ +++SD S+ EF IPK V + + + Sbjct: 352 MLEATIREVLRIRPVAPMLIPHRANSDMSIG-----EFSIPKFTPVIINLWALHHSEKEW 406 Query: 488 KNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFE 309 PD + P+RF + + SY+ FG G C+GE A ++ HLL+ F+ + Sbjct: 407 DQPDRFMPERFLDPTGSHLITPSLSYLPFGAGARSCIGEVLARQELFLFMAHLLQRFDLD 466 Query: 308 L 306 + Sbjct: 467 V 467
>C76C1_ARATH (O64636) Cytochrome P450 76C1 (EC 1.14.-.-)| Length = 512 Score = 55.1 bits (131), Expect = 2e-07 Identities = 35/131 (26%), Positives = 64/131 (48%), Gaps = 1/131 (0%) Frame = -2 Query: 695 IDHDILAEMDVLYRCIKEALRLHPPLIMLL-RQSHSDFSVTTREGKEFDIPKGHIVATSP 519 ++ ++++ L +KE RLH P+ +L+ R++ SD + F + K V + Sbjct: 351 VEESDISKLPYLQAVVKETFRLHTPVPLLIPRKAESDAEILG-----FMVLKDTQVLVNV 405 Query: 518 AFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIW 339 R P ++ NP ++P+RF G++ D + FG GR C G P A + + Sbjct: 406 WAIGRDPSVWDNPSQFEPERFL-GKDMDVRGRDYELTPFGAGRRICPGMPLAMKTVSLML 464 Query: 338 THLLRNFEFEL 306 LL +F+++L Sbjct: 465 ASLLYSFDWKL 475
>C71C4_MAIZE (Q43257) Cytochrome P450 71C4 (EC 1.14.-.-) (Benzoxazineless 2)| Length = 538 Score = 55.1 bits (131), Expect = 2e-07 Identities = 40/143 (27%), Positives = 66/143 (46%), Gaps = 3/143 (2%) Frame = -2 Query: 701 DKIDHDILAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATS 522 + + D L M L IKE LRLHPP+ +LL +S+ E + IP V + Sbjct: 376 EMVTEDNLPGMTDLKAVIKETLRLHPPVPLLLPH----YSLDACEVAGYTIPANTRVVVN 431 Query: 521 PAFANRLPHIFKNPDSYDPDRFAAGREE---DKVAGAFSYISFGGGRHGCLGEPFAYLQI 351 R ++ + + P+RF +G D F +++FG GR C G A I Sbjct: 432 AWALGRHSGYWERENEFVPERFLSGDVAGGVDLKPNEFQFLAFGSGRRMCPGVHSASATI 491 Query: 350 KAIWTHLLRNFEFELVSPFPEND 282 +A+ ++L+ F+++L + D Sbjct: 492 EAMLSNLMYRFDWQLPAGMKAED 514
>C28D1_DROME (Q9VMT5) Probable cytochrome P450 28d1 (EC 1.14.-.-) (CYPXXVIIID1)| Length = 502 Score = 55.1 bits (131), Expect = 2e-07 Identities = 41/159 (25%), Positives = 71/159 (44%), Gaps = 7/159 (4%) Frame = -2 Query: 680 LAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFANRL 501 ++E+ CI E LR+ P++ + +T + G + G +V + Sbjct: 346 ISELPFTEACIHETLRIFSPVLAARKVVTEPCELTNKNGVSVKLRPGDVVIIPVNALHHD 405 Query: 500 PHIFKNPDSYDPDRFA---AGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHL 330 P ++ P S+ P+RF G ++ + G F FG G C G F+ QIKA + Sbjct: 406 PQYYEEPQSFKPERFLNINGGAKKYRDQGLF--FGFGDGPRICPGMRFSLTQIKAALVEI 463 Query: 329 LRNFEFELVSPFP----ENDWNAMVVGIKGEVMVNYKRR 225 +RNF+ + V+P E D + +KG V +++ R Sbjct: 464 VRNFDIK-VNPKTRKDNEIDDTYFMPALKGGVWLDFVER 501
>C71E1_SORBI (O48958) Cytochrome P450 71E1 (EC 1.14.13.68)| (4-hydroxyphenylacetaldehyde oxime monooxygenase) Length = 531 Score = 55.1 bits (131), Expect = 2e-07 Identities = 38/140 (27%), Positives = 63/140 (45%), Gaps = 1/140 (0%) Frame = -2 Query: 698 KIDHDILAEMDVLYRCIKEALRLHPPLIMLL-RQSHSDFSVTTREGKEFDIPKGHIVATS 522 +++ + A++ L +KE LRLHPP +L+ R++ D ++ +D+P V + Sbjct: 368 RVNSEDAAKIPYLKMVVKETLRLHPPATLLVPRETMRDTTIC-----GYDVPANTRVFVN 422 Query: 521 PAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAI 342 R P + PD ++PDRF G + D F I FG GR C G + Sbjct: 423 AWAIGRDPASWPAPDEFNPDRF-VGSDVDYYGSHFELIPFGAGRRICPGLTMGETNVTFT 481 Query: 341 WTHLLRNFEFELVSPFPEND 282 +LL +++ L D Sbjct: 482 LANLLYCYDWALPGAMKPED 501
>C11B1_RAT (P15393) Cytochrome P450 11B1, mitochondrial precursor (EC| 1.14.15.4) (CYPXIB1) (P450C11) (Steroid 11-beta-hydroxylase) (P450(11 beta)-DS) Length = 499 Score = 54.7 bits (130), Expect = 3e-07 Identities = 33/124 (26%), Positives = 60/124 (48%) Frame = -2 Query: 680 LAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFANRL 501 ++++ +L +KE LRL+P + R HSD + + + +P G V R Sbjct: 358 MSDLPLLRAALKETLRLYPVGSFVERIVHSDLVL-----QNYHVPAGTFVIIYLYSMGRN 412 Query: 500 PHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRN 321 P +F P+ Y P R+ + +F +++FG G CLG A +++ + H+L+ Sbjct: 413 PAVFPRPERYMPQRWLERKR------SFQHLAFGFGVRQCLGRRLAEVEMLLLLHHMLKT 466 Query: 320 FEFE 309 F+ E Sbjct: 467 FQVE 470
>CP51_ISSOR (Q02315) Cytochrome P450 51 (EC 1.14.13.70) (CYPLI) (P450-LIA1)| (Sterol 14-alpha demethylase) (Lanosterol 14-alpha demethylase) (P450-14DM) (Fragment) Length = 414 Score = 54.7 bits (130), Expect = 3e-07 Identities = 39/129 (30%), Positives = 53/129 (41%), Gaps = 23/129 (17%) Frame = -2 Query: 698 KIDHDILAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSP 519 ++ +D L ++D++ IKE LRLH PL + R+ D V + +PKGH V SP Sbjct: 288 ELTYDDLQKLDLVNATIKETLRLHMPLHSIFRKVTRDLPV---PNTSYIVPKGHYVLISP 344 Query: 518 AFANRLPHIFKNPDSYDPDR------------FAAGREEDK-----------VAGAFSYI 408 + F N + P R F A E K A Y+ Sbjct: 345 GYTMLSERYFPNASEFQPHRWDEIKSIDGGISFGAEGENAKETVDYGFGKISKGVASPYL 404 Query: 407 SFGGGRHGC 381 FGGGRH C Sbjct: 405 PFGGGRHRC 413
>CP52V_CANAP (P43083) Cytochrome P450 52E1 (EC 1.14.14.-) (CYPLIIE1)| Length = 519 Score = 54.7 bits (130), Expect = 3e-07 Identities = 46/144 (31%), Positives = 66/144 (45%), Gaps = 7/144 (4%) Frame = -2 Query: 680 LAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFD----IPKGHIVATSPAF 513 L + VL I+E LRLHP + + RQ+ D + T G D +PKG V S Sbjct: 359 LKQCKVLQNVIREVLRLHPNVPLNFRQAIVDTKLPTGGGPNGDQPVFVPKGQNVFYSTYS 418 Query: 512 ANRLPHIFKNPD--SYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIW 339 R I+ PD ++ PDR+ RE +A + YI F GG CLG+ FA + Sbjct: 419 MQRRTDIW-GPDATTFRPDRWNEPRE--ALASGWDYIPFNGGPRICLGQQFALTEASYTI 475 Query: 338 THLLRNF-EFELVSPFPENDWNAM 270 + + F E++ P N+M Sbjct: 476 VRICQEFSRIEVLHPDVITSKNSM 499
>F3PH_PETHY (Q9SBQ9) Flavonoid 3'-monooxygenase (EC 1.14.13.21) (Flavonoid| 3'-hydroxylase) (Cytochrome P450 75B2) Length = 512 Score = 54.7 bits (130), Expect = 3e-07 Identities = 39/130 (30%), Positives = 61/130 (46%), Gaps = 3/130 (2%) Frame = -2 Query: 680 LAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFANRL 501 LA++ L +KE RLHP + L + S+ + E + IPKG + + R Sbjct: 349 LAQLTYLEAIVKETFRLHPSTPLSLPRIASE----SCEINGYFIPKGSTLLLNVWAIARD 404 Query: 500 PHIFKNPDSYDPDRFAAGREEDKV---AGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHL 330 P+ + +P + P+RF G E+ KV F I FG GR C G ++ + L Sbjct: 405 PNAWADPLEFRPERFLPGGEKPKVDVRGNDFEVIPFGAGRRICAGMNLGIRMVQLMIATL 464 Query: 329 LRNFEFELVS 300 + F ++LVS Sbjct: 465 IHAFNWDLVS 474
>CP3AV_MESAU (O70537) Cytochrome P450 3A31 (EC 1.14.14.1) (CYPIIIA31) (P450| SH3A-1) Length = 501 Score = 54.7 bits (130), Expect = 3e-07 Identities = 39/128 (30%), Positives = 60/128 (46%), Gaps = 1/128 (0%) Frame = -2 Query: 689 HDILAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFA 510 +D + EM+ L + E LRL+P L R D E +PKG IV P FA Sbjct: 345 YDKVMEMEYLDMVLNETLRLYPIGSRLERVCKQDV-----EMDGVFVPKGSIVMV-PVFA 398 Query: 509 NRL-PHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTH 333 P + P+ + P+RF+ +E + ++ FG G C+G FA + +K T Sbjct: 399 LHYDPQYWPEPEKFRPERFS--KENKGSIDPYIFLPFGNGPRNCIGMRFALMNMKLALTK 456 Query: 332 LLRNFEFE 309 +L+NF + Sbjct: 457 VLQNFSLQ 464
>CP11B_RANCA (Q92104) Cytochrome P450 11B, mitochondrial precursor (EC| 1.14.15.4) (CYPXIB) (P450C11) (Steroid 11-beta-hydroxylase) (P-450(11 beta,aldo)) Length = 517 Score = 54.7 bits (130), Expect = 3e-07 Identities = 37/130 (28%), Positives = 60/130 (46%) Frame = -2 Query: 689 HDILAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFA 510 + +L + +L IKE LRL+P I + R D + + IP G +V Sbjct: 373 NQLLNSLPLLKGAIKETLRLYPVGITVQRHLIKDIVL-----HNYHIPAGTLVQVGLYPM 427 Query: 509 NRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHL 330 R P +F++ YDP R+ + + F ++FG G C+G A +I H+ Sbjct: 428 GRSPLLFQDALRYDPARWLKREDTN-----FKALAFGFGSRQCIGRRIAETEITLFLMHM 482 Query: 329 LRNFEFELVS 300 L+NF+ + VS Sbjct: 483 LKNFQIDTVS 492
>C11B1_CAVPO (Q64408) Cytochrome P450 11B1, mitochondrial precursor (EC| 1.14.15.4) (CYPXIB1) (P450C11) (Steroid 11-beta-hydroxylase) (Aldosterone synthase) Length = 500 Score = 54.3 bits (129), Expect = 4e-07 Identities = 32/119 (26%), Positives = 60/119 (50%) Frame = -2 Query: 674 EMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFANRLPH 495 E+ +L+ IKE LR++P + L R F + + + IP G +V + R P Sbjct: 361 ELPLLWAAIKETLRMYPVGLFLER-----FLTSPLVLQNYHIPAGTLVHLNLYSMGRNPE 415 Query: 494 IFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNF 318 +F +P+ Y+P R+ +E + +++FG G C+G A +++ H+L++F Sbjct: 416 VFLSPEHYNPQRWLENKE------TYKHLAFGFGVRQCIGRRLAEVEMLLFLHHVLKSF 468
>CP3AL_CALJA (O18993) Cytochrome P450 3A21 (EC 1.14.14.1) (CYPIIIA21) (P450| CM3A-10) Length = 503 Score = 54.3 bits (129), Expect = 4e-07 Identities = 36/128 (28%), Positives = 61/128 (47%), Gaps = 1/128 (0%) Frame = -2 Query: 689 HDILAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFA 510 +D + +M+ L + E LRL P + L R D + IPKG +V P++A Sbjct: 347 YDTVLQMEYLDMVVNETLRLFPLAMRLERVCKKDVEING-----VFIPKG-VVVMIPSYA 400 Query: 509 NRL-PHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTH 333 P + P+ + P+RF+ +++ + Y FG G C+G FA + +K Sbjct: 401 LHYDPKYWTEPEKFLPERFSKNNKDN--IDPYIYTPFGTGPRNCIGMRFALMNMKLALIR 458 Query: 332 LLRNFEFE 309 +L+NF F+ Sbjct: 459 VLQNFSFK 466
>CP52W_CANAP (Q12573) Cytochrome P450 52E2 (EC 1.14.14.-) (CYPLIIE2)| Length = 519 Score = 53.9 bits (128), Expect = 5e-07 Identities = 43/135 (31%), Positives = 64/135 (47%), Gaps = 7/135 (5%) Frame = -2 Query: 680 LAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFD----IPKGHIVATSPAF 513 L + VL I+E LRLHP + + R++ +D + T G D +PKG V + Sbjct: 359 LKQCKVLQNVIREVLRLHPNVPLNFREAIADTTFPTGGGPNGDQPIFVPKGQKVFYATYV 418 Query: 512 ANRLPHIFKNPD--SYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIW 339 R I+ PD S+ PDR+ RE +A + YI F GG CLG+ FA + Sbjct: 419 MQRNAGIW-GPDSTSFRPDRWNEPRE--ALASGWDYIPFNGGPRICLGQQFALTEASYTL 475 Query: 338 THLLRNF-EFELVSP 297 + + F E++ P Sbjct: 476 VRICQEFSRIEVLHP 490
>C71B5_ARATH (O65784) Cytochrome P450 71B5 (EC 1.14.-.-)| Length = 498 Score = 53.9 bits (128), Expect = 5e-07 Identities = 41/141 (29%), Positives = 65/141 (46%), Gaps = 1/141 (0%) Frame = -2 Query: 701 DKIDHDILAEMDVLYRCIKEALRLHPPLIMLL-RQSHSDFSVTTREGKEFDIPKGHIVAT 525 +KI + L +++ L I+EA RLHPP +LL R + SD ++ + + IPK ++ Sbjct: 338 EKITEEDLEKVEYLKMVIEEAFRLHPPAPLLLPRLTMSDINI-----QGYSIPKNTMIQI 392 Query: 524 SPAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKA 345 + R P + PD + P+RF E K F + FG GR C G ++ Sbjct: 393 NTYTIGRDPKNWTKPDEFIPERFVDNPIEYK-GQHFELLPFGAGRRVCPGMATGITIVEL 451 Query: 344 IWTHLLRNFEFELVSPFPEND 282 LL F++ L + D Sbjct: 452 GLLSLLYFFDWSLPNGMTTKD 472
>C71B4_ARATH (O65786) Cytochrome P450 71B4 (EC 1.14.-.-)| Length = 504 Score = 53.9 bits (128), Expect = 5e-07 Identities = 38/132 (28%), Positives = 65/132 (49%), Gaps = 1/132 (0%) Frame = -2 Query: 698 KIDHDILAEMDVLYRCIKEALRLHPPLIMLL-RQSHSDFSVTTREGKEFDIPKGHIVATS 522 +I + L ++ L +KE LRLHP +LL R++ +D + + +DIP+ + + Sbjct: 346 RIMEEDLDKLQYLKLVVKETLRLHPAAPLLLPRETMADIKI-----QGYDIPQKRALLVN 400 Query: 521 PAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAI 342 R P +KNP+ ++P+RF D +F + FG GR C G A I+ Sbjct: 401 AWSIGRDPESWKNPEEFNPERF-IDCPVDYKGHSFELLPFGSGRRICPGIAMAIATIELG 459 Query: 341 WTHLLRNFEFEL 306 +LL F++ + Sbjct: 460 LLNLLYFFDWNM 471
>C97B3_ARATH (O23365) Cytochrome P450 97B3 (EC 1.14.-.-)| Length = 580 Score = 53.9 bits (128), Expect = 5e-07 Identities = 35/153 (22%), Positives = 71/153 (46%), Gaps = 25/153 (16%) Frame = -2 Query: 689 HDILAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVT-----TREGKEFDIPKGHIVAT 525 ++ + +++ + + E LRL P +L+R++ ++ +EG + +PKG + Sbjct: 400 YESMKKLEYIRLIVVEVLRLFPQPPLLIRRTLKPETLPGGHKGEKEGHK--VPKGTDIFI 457 Query: 524 SPAFANRLPHIFKNPDSYDPDRFAAGREEDKVAG--------------------AFSYIS 405 S +R P+ + NP ++P+RF +E + + G F+++ Sbjct: 458 SVYNLHRSPYFWDNPHDFEPERFLRTKESNGIEGWAGFDPSRSPGALYPNEIIADFAFLP 517 Query: 404 FGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFEL 306 FGGG C+G+ FA ++ L + F+ EL Sbjct: 518 FGGGPRKCIGDQFALMESTVALAMLFQKFDVEL 550
>CP7A1_MOUSE (Q64505) Cytochrome P450 7A1 (EC 1.14.13.17) (Cholesterol| 7-alpha-monooxygenase) (CYPVII) (Cholesterol 7-alpha-hydroxylase) Length = 503 Score = 53.9 bits (128), Expect = 5e-07 Identities = 42/138 (30%), Positives = 65/138 (47%), Gaps = 7/138 (5%) Frame = -2 Query: 695 IDHDILAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPA 516 +D + L + VL IKEALRL + + R + DF++ +G ++I K I+A P Sbjct: 335 LDQEQLNNLPVLDSIIKEALRLSSASLNI-RTAKEDFTLHLEDGS-YNIRKDDIIALYPQ 392 Query: 515 FANRLPHIFKNPDSYDPDRFAAGREEDKVAG-------AFSYISFGGGRHGCLGEPFAYL 357 + P I+ +P ++ DR+ + K + Y+ FG G C G FA Sbjct: 393 LMHLDPEIYPDPLTFKYDRYLDESGKAKTTFYRNGNKLKYFYMPFGSGATICPGRLFAVQ 452 Query: 356 QIKAIWTHLLRNFEFELV 303 +IK +L FE ELV Sbjct: 453 EIKQFLILMLSYFELELV 470
>C93B1_GLYEC (P93149) Cytochrome P450 93B1 (EC 1.14.13.87) (Licodione synthase)| ((2S)-flavanone 2-hydroxylase) (Flavone synthase II) (CYP GE-5) Length = 523 Score = 53.5 bits (127), Expect = 6e-07 Identities = 35/127 (27%), Positives = 62/127 (48%), Gaps = 5/127 (3%) Frame = -2 Query: 662 LYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFANRLPHIFKN 483 L +KE RLHPP+ M+ R+ ++ +V + + IP+ ++ + R P + N Sbjct: 355 LQAILKETFRLHPPVPMVTRRCVAECTV-----ENYVIPEDSLLFVNVWSIGRNPKFWDN 409 Query: 482 PDSYDPDRFAAGREEDK----VAGA-FSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNF 318 P + P+RF + V G+ F + FG GR C G A ++ A+ +++ F Sbjct: 410 PLEFRPERFLKLEGDSSGVVDVRGSHFQLLPFGSGRRMCPGVSLAMQEVPALLGAIIQCF 469 Query: 317 EFELVSP 297 +F +V P Sbjct: 470 DFHVVGP 476
>C71B8_ARATH (P58048) Cytochrome P450 71B8 (EC 1.14.-.-)| Length = 506 Score = 53.5 bits (127), Expect = 6e-07 Identities = 39/133 (29%), Positives = 62/133 (46%), Gaps = 1/133 (0%) Frame = -2 Query: 701 DKIDHDILAEMDVLYRCIKEALRLHPPLIMLL-RQSHSDFSVTTREGKEFDIPKGHIVAT 525 ++I + L +++ L IKE RLHPP LL RQ SD + + + IPK + Sbjct: 342 ERITEEDLEKVEYLKLVIKETFRLHPPGPFLLPRQVMSDIEI-----QGYHIPKNAHIKI 396 Query: 524 SPAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKA 345 S R P + NP+ ++P+RFA K + + FG GR C G ++ Sbjct: 397 STYAIGRDPKCWTNPEEFNPERFANTSINYK-GQHYELLPFGAGRRSCPGMTLGITILEL 455 Query: 344 IWTHLLRNFEFEL 306 ++L F++ L Sbjct: 456 GLLNILYYFDWSL 468
>CP138_MYCTU (P63717) Putative cytochrome P450 138 (EC 1.14.-.-)| Length = 441 Score = 53.5 bits (127), Expect = 6e-07 Identities = 26/84 (30%), Positives = 45/84 (53%) Frame = -2 Query: 560 EFDIPKGHIVATSPAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGC 381 E+ IP+G+ + + A + P +F PD +DP R+ + F++I FGGG C Sbjct: 334 EWVIPRGYSIIINIAQIHGDPDVFPQPDRFDPQRYIGSKPSP-----FAWIPFGGGTRRC 388 Query: 380 LGEPFAYLQIKAIWTHLLRNFEFE 309 +G FA +++ + +LR+F E Sbjct: 389 VGAAFANMEMDVVLRTVLRHFTLE 412
>CP138_MYCBO (P63718) Putative cytochrome P450 138 (EC 1.14.-.-)| Length = 441 Score = 53.5 bits (127), Expect = 6e-07 Identities = 26/84 (30%), Positives = 45/84 (53%) Frame = -2 Query: 560 EFDIPKGHIVATSPAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGC 381 E+ IP+G+ + + A + P +F PD +DP R+ + F++I FGGG C Sbjct: 334 EWVIPRGYSIIINIAQIHGDPDVFPQPDRFDPQRYIGSKPSP-----FAWIPFGGGTRRC 388 Query: 380 LGEPFAYLQIKAIWTHLLRNFEFE 309 +G FA +++ + +LR+F E Sbjct: 389 VGAAFANMEMDVVLRTVLRHFTLE 412
>C81D1_ARATH (Q9FG65) Cytochrome P450 81D1 (EC 1.14.-.-)| Length = 502 Score = 53.5 bits (127), Expect = 6e-07 Identities = 38/131 (29%), Positives = 64/131 (48%) Frame = -2 Query: 695 IDHDILAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPA 516 I+ L+E+ L + E LRLHP +L+ S+ + G +D+P+G + + Sbjct: 346 IEEADLSELPYLKNIVLETLRLHPATPLLVPHMASE---DCKIGS-YDMPRGTTLLVNAW 401 Query: 515 FANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWT 336 +R P+ + +PDS+ P+RF E K+ ++FG GR C G A + Sbjct: 402 AIHRDPNTWDDPDSFKPERFEKEEEAQKL------LAFGLGRRACPGSGLAQRIVGLALG 455 Query: 335 HLLRNFEFELV 303 L++ FE+E V Sbjct: 456 SLIQCFEWERV 466
>C4AC1_DROME (Q9VMS9) Probable cytochrome P450 4ac1 (EC 1.14.-.-) (CYPIVAC1)| Length = 509 Score = 53.5 bits (127), Expect = 6e-07 Identities = 33/112 (29%), Positives = 55/112 (49%) Frame = -2 Query: 650 IKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFANRLPHIFKNPDSY 471 IKE+LR+ P + + RQ + V +PK ++ R P F PD + Sbjct: 372 IKESLRMFPSVPFIGRQCVEETVVNGMV-----MPKDTQISIHIYDIMRDPRHFPKPDLF 426 Query: 470 DPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFE 315 PDRF ++ F+Y+ F G+ C+G+ FA L++K + ++RNF+ Sbjct: 427 QPDRFLPENTVNR--HPFAYVPFSAGQRNCIGQKFAILEMKVLLAAVIRNFK 476
>C71BM_ARATH (Q9LTM1) Cytochrome P450 71B22 (EC 1.14.-.-)| Length = 500 Score = 53.5 bits (127), Expect = 6e-07 Identities = 34/110 (30%), Positives = 57/110 (51%), Gaps = 1/110 (0%) Frame = -2 Query: 701 DKIDHDILAEMDVLYRCIKEALRLHPPLIMLL-RQSHSDFSVTTREGKEFDIPKGHIVAT 525 +KI L ++ L I+E RLHPP +LL R++ SD + + ++IPK ++ Sbjct: 340 EKITEQDLEKVHYLKLVIEETFRLHPPAPLLLPRETMSDLKI-----QGYNIPKNTMIEI 394 Query: 524 SPAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLG 375 + R P+ ++NP+ ++P+RF E K + + FG GR C G Sbjct: 395 NTYSIGRDPNCWENPNDFNPERFIDSPVEYK-GQHYELLPFGAGRRICPG 443
>C71D8_SOYBN (O81974) Cytochrome P450 71D8 (EC 1.14.-.-) (P450 CP7)| Length = 504 Score = 53.5 bits (127), Expect = 6e-07 Identities = 40/133 (30%), Positives = 58/133 (43%) Frame = -2 Query: 680 LAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFANRL 501 L E+ L IKE LRLHPP ++ R+ + + ++IP V + R Sbjct: 351 LEELSYLKSVIKETLRLHPPSQLIPREC-----IISTNIDGYEIPIKTKVMINTWAIGRD 405 Query: 500 PHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRN 321 P + + D + P+RF + K +F YI FG GR C G F I LL + Sbjct: 406 PQYWSDADRFIPERFNDSSIDFK-GNSFEYIPFGAGRRMCPGMTFGLASITLPLALLLYH 464 Query: 320 FEFELVSPFPEND 282 F +EL + D Sbjct: 465 FNWELPNKMKPED 477
>CP3A8_MACFA (P33268) Cytochrome P450 3A8 (EC 1.14.14.1) (CYPIIIA8) (P450-MKNF2)| (P-450-MK2) Length = 503 Score = 53.5 bits (127), Expect = 6e-07 Identities = 33/127 (25%), Positives = 57/127 (44%) Frame = -2 Query: 689 HDILAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFA 510 +D + +M+ L + E LR+ P + L R D + IPKG +V Sbjct: 347 YDTVLQMEYLDMVVNETLRIFPIAMRLERVCKKDVEING-----IFIPKGVVVMIPSYAL 401 Query: 509 NRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHL 330 + P + P+ + P+RF+ ++ + Y FG G C+G FA + +K + Sbjct: 402 HHDPKYWPEPEKFLPERFSKKNNDN--IDPYIYTPFGSGPRNCIGMRFALMNMKLAIIRV 459 Query: 329 LRNFEFE 309 L+NF F+ Sbjct: 460 LQNFSFK 466
>C11B1_PAPHU (Q29527) Cytochrome P450 11B1, mitochondrial precursor (EC| 1.14.15.4) (CYPXIB1) (P450C11) (Steroid 11-beta-hydroxylase) Length = 503 Score = 53.5 bits (127), Expect = 6e-07 Identities = 35/125 (28%), Positives = 60/125 (48%) Frame = -2 Query: 674 EMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFANRLPH 495 E+ +L +KE LRL+P + L R SD + + + IP G +V R P Sbjct: 361 ELPLLRAALKETLRLYPVGLFLERVVSSDLVL-----QNYHIPAGTLVRVFLYSLGRNPA 415 Query: 494 IFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFE 315 +F P+ Y+P R+ R + F ++ FG G CLG A ++ + H+L++ + Sbjct: 416 LFPRPERYNPQRWLDIRGSGR---NFYHVPFGFGMRQCLGRRLAEAEMLLLLHHVLKHLQ 472 Query: 314 FELVS 300 E ++ Sbjct: 473 VETLT 477
>C11B1_HUMAN (P15538) Cytochrome P450 11B1, mitochondrial precursor (EC| 1.14.15.4) (CYPXIB1) (P450C11) (P-450c11) (Steroid 11-beta-hydroxylase) Length = 503 Score = 53.5 bits (127), Expect = 6e-07 Identities = 35/125 (28%), Positives = 60/125 (48%) Frame = -2 Query: 674 EMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFANRLPH 495 E+ +L +KE LRL+P + L R SD + + + IP G +V R P Sbjct: 361 ELPLLRAALKETLRLYPVGLFLERVVSSDLVL-----QNYHIPAGTLVRVFLYSLGRNPA 415 Query: 494 IFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFE 315 +F P+ Y+P R+ R + F ++ FG G CLG A ++ + H+L++ + Sbjct: 416 LFPRPERYNPQRWLDIRGSGR---NFYHVPFGFGMRQCLGRRLAEAEMLLLLHHVLKHLQ 472 Query: 314 FELVS 300 E ++ Sbjct: 473 VETLT 477
>C11B2_RAT (P30099) Cytochrome P450 11B2, mitochondrial precursor (EC| 1.14.15.4) (EC 1.14.15.5) (CYPXIB2) (P450-Aldo-1) (Aldosterone synthase) Length = 510 Score = 53.1 bits (126), Expect = 8e-07 Identities = 33/124 (26%), Positives = 61/124 (49%) Frame = -2 Query: 680 LAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFANRL 501 ++++ +L +KE LRL+P L R +SD + + + +P G +V R Sbjct: 369 MSDLPLLRAALKETLRLYPVGGFLERILNSDLVL-----QNYHVPAGTLVLLYLYSMGRN 423 Query: 500 PHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRN 321 P +F P+ Y P R+ + +F +++FG G CLG A +++ + H+L+ Sbjct: 424 PAVFPRPERYMPQRWLERKR------SFQHLAFGFGVRQCLGRRLAEVEMLLLLHHMLKT 477 Query: 320 FEFE 309 F+ E Sbjct: 478 FQVE 481
>C71BL_ARATH (Q9LTM2) Cytochrome P450 71B21 (EC 1.14.-.-)| Length = 499 Score = 53.1 bits (126), Expect = 8e-07 Identities = 35/110 (31%), Positives = 56/110 (50%), Gaps = 1/110 (0%) Frame = -2 Query: 701 DKIDHDILAEMDVLYRCIKEALRLHPPLIMLL-RQSHSDFSVTTREGKEFDIPKGHIVAT 525 +KI L ++ L I+E RLHPP +LL R++ SD + + ++IPK ++ Sbjct: 340 EKITEQDLEKVHYLKLVIQETFRLHPPAPLLLPRETMSDVKI-----QGYNIPKNTMIEI 394 Query: 524 SPAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLG 375 + R P+ + NP+ + P+RF + K F + FGGGR C G Sbjct: 395 NTYAIGRDPNCWTNPNEFIPERFVDSPIDYK-GQHFELLPFGGGRRICPG 443
>C76C2_ARATH (O64637) Cytochrome P450 76C2 (EC 1.14.-.-)| Length = 512 Score = 53.1 bits (126), Expect = 8e-07 Identities = 36/131 (27%), Positives = 63/131 (48%), Gaps = 1/131 (0%) Frame = -2 Query: 695 IDHDILAEMDVLYRCIKEALRLHPPLIMLL-RQSHSDFSVTTREGKEFDIPKGHIVATSP 519 ++ ++ + L +KE RLHP +L+ R++ SD V F +PK V + Sbjct: 352 VEESDISALPYLQAVVKETFRLHPAAPLLVPRKAESDVEVLG-----FMVPKDTQVFVNV 406 Query: 518 AFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIW 339 R P++++N + P+RF G++ D + FG GR C G P A + + Sbjct: 407 WAIGRDPNVWENSSRFKPERFL-GKDIDLRGRDYELTPFGAGRRICPGLPLAVKTVPLML 465 Query: 338 THLLRNFEFEL 306 LL +F+++L Sbjct: 466 ASLLYSFDWKL 476
>C71BU_ARATH (Q9SCN2) Cytochrome P450 71B31 (EC 1.14.-.-)| Length = 498 Score = 53.1 bits (126), Expect = 8e-07 Identities = 38/135 (28%), Positives = 65/135 (48%), Gaps = 1/135 (0%) Frame = -2 Query: 701 DKIDHDILAEMDVLYRCIKEALRLHPPLIMLL-RQSHSDFSVTTREGKEFDIPKGHIVAT 525 ++I + L +++ L IKE+ RLHPP +LL R++ SD + + + IPK V Sbjct: 340 ERITEEDLEKVEYLNLVIKESFRLHPPAPLLLPRETMSDIEI-----QGYHIPKNAHVKI 394 Query: 524 SPAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKA 345 + R P + NP+ ++P+RF K + + FG GR C G ++ Sbjct: 395 NTYAIGRDPKRWTNPEEFNPERFLNTSINYK-GQHYELLPFGAGRRNCPGMTLGITILEL 453 Query: 344 IWTHLLRNFEFELVS 300 ++L F++ L S Sbjct: 454 GLLNILYYFDWSLPS 468
>C11B3_RAT (P30100) Cytochrome P450 11B3, mitochondrial precursor (EC| 1.14.15.4) (EC 1.14.15.5) (CYPXIB3) (P450-Aldo-2) (Aldosterone synthase) Length = 500 Score = 53.1 bits (126), Expect = 8e-07 Identities = 33/124 (26%), Positives = 61/124 (49%) Frame = -2 Query: 680 LAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFANRL 501 ++++ +L +KE LRL+P L R +SD + + + +P G +V R Sbjct: 359 MSDLPLLRAALKETLRLYPVGGFLERILNSDLVL-----QNYHVPAGTLVLLYLYSMGRN 413 Query: 500 PHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRN 321 P +F P+ Y P R+ + +F +++FG G CLG A +++ + H+L+ Sbjct: 414 PAVFPRPERYMPQRWLERKR------SFQHLAFGFGVRQCLGRRLAEVEMLLLLHHMLKT 467 Query: 320 FEFE 309 F+ E Sbjct: 468 FQVE 471
>C11B2_MESAU (Q64658) Cytochrome P450 11B2, mitochondrial precursor (EC| 1.14.15.4) (EC 1.14.15.5) (C450XIB2) (Aldosterone synthase) (P-450Aldo) (ALDOS) (Aldosterone-synthesizing enzyme) (Steroid 18-hydroxylase) (P-450C18) Length = 500 Score = 53.1 bits (126), Expect = 8e-07 Identities = 34/124 (27%), Positives = 61/124 (49%) Frame = -2 Query: 680 LAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFANRL 501 ++++ +L +KE LRL+P L R SD + + + +P G +V R Sbjct: 359 MSDLPLLRAVLKETLRLYPVGGFLERILSSDLVL-----QNYHVPAGTLVLLYLYSMGRN 413 Query: 500 PHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRN 321 P +F P+ Y P R+ G+F +++FG G CLG+ A +++ + H+L++ Sbjct: 414 PAVFPRPEHYLPQRWLERN------GSFQHLTFGFGVRQCLGKRLAQVEMLLLLHHVLKS 467 Query: 320 FEFE 309 F E Sbjct: 468 FRVE 471
>CP7A1_CRIGR (P46634) Cytochrome P450 7A1 (EC 1.14.13.17) (Cholesterol| 7-alpha-monooxygenase) (CYPVII) (Cholesterol 7-alpha-hydroxylase) Length = 504 Score = 53.1 bits (126), Expect = 8e-07 Identities = 42/138 (30%), Positives = 66/138 (47%), Gaps = 7/138 (5%) Frame = -2 Query: 695 IDHDILAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPA 516 +D L + VL IKEALRL + + R + DF++ +G ++I K I+A P Sbjct: 335 LDQIQLNNLPVLDSIIKEALRLSSASLNI-RTAKEDFTLHLEDGS-YNIRKDDIIALYPQ 392 Query: 515 FANRLPHIFKNPDSYDPDRFAAGREEDKVAG-------AFSYISFGGGRHGCLGEPFAYL 357 + P I+ +P ++ DR+ ++ K + + Y+ FG G C G FA Sbjct: 393 LMHLDPAIYPDPLTFKYDRYLDENKKAKTSFYSNGNKLKYFYMPFGSGATICPGRLFAVQ 452 Query: 356 QIKAIWTHLLRNFEFELV 303 +IK +L FE ELV Sbjct: 453 EIKQFLILMLSYFELELV 470
>C6A21_DROME (Q9V774) Probable cytochrome P450 6a21 (EC 1.14.-.-) (CYPVIA21)| Length = 504 Score = 53.1 bits (126), Expect = 8e-07 Identities = 31/131 (23%), Positives = 69/131 (52%) Frame = -2 Query: 698 KIDHDILAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSP 519 +++++ + ++ L + + E LRL+ L +L R+ D+ V ++ I KG V Sbjct: 348 ELNYESMKDLVYLDQVVSETLRLYTVLPVLNRECLEDYEVPGHP--KYVIKKGMPVLIPC 405 Query: 518 AFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIW 339 +R ++ NP++++PD F+ R +++ + ++ FG G C+G F +Q + Sbjct: 406 GAMHRDEKLYANPNTFNPDNFSPERVKER--DSVEWLPFGDGPRNCIGMRFGQMQARIGL 463 Query: 338 THLLRNFEFEL 306 L+++F+F + Sbjct: 464 ALLIKDFKFSV 474
>CP27A_RAT (P17178) Cytochrome P450 27, mitochondrial precursor (EC| 1.14.13.15) (Cytochrome P-450C27/25) (Sterol 26-hydroxylase) (Sterol 27-hydroxylase) (Vitamin D(3) 25-hydroxylase) (5-beta-cholestane-3-alpha,7-alpha,12-alpha-triol 27-hydroxylase) Length = 533 Score = 53.1 bits (126), Expect = 8e-07 Identities = 36/126 (28%), Positives = 58/126 (46%), Gaps = 2/126 (1%) Frame = -2 Query: 677 AEMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFANRLP 498 A M +L IKE LRL+P ++ + + E F PK +R P Sbjct: 383 AHMPLLKAVIKETLRLYP----VVPTNSRIITEKETEINGFLFPKNTQFVLCHYVVSRDP 438 Query: 497 HIFKNPDSYDPDRFAAGREEDK--VAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLR 324 +F P+S+ P R+ RE+D + F + FG G CLG A L+++ + + L++ Sbjct: 439 SVFPEPESFQPHRWLRKREDDNSGIQHPFGSVPFGYGVRSCLGRRIAELEMQLLLSRLIQ 498 Query: 323 NFEFEL 306 +E L Sbjct: 499 KYEVVL 504
>C71BF_ARATH (Q9LW27) Cytochrome P450 71B15 (EC 1.14.-.-)| Length = 490 Score = 52.8 bits (125), Expect = 1e-06 Identities = 36/133 (27%), Positives = 64/133 (48%), Gaps = 1/133 (0%) Frame = -2 Query: 701 DKIDHDILAEMDVLYRCIKEALRLHPPLIMLL-RQSHSDFSVTTREGKEFDIPKGHIVAT 525 ++I + L ++ +KE LRLHP +LL RQ+ S + + +D+P + Sbjct: 339 ERIKEEDLNQLHYFKLVVKETLRLHPTTPLLLPRQTMSHIKI-----QGYDVPAKTQILV 393 Query: 524 SPAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKA 345 + R P +++N D ++PDRF + K + +I FG GR C G + ++ Sbjct: 394 NVYAMGRDPKLWENADEFNPDRFLDSSVDFK-GKNYEFIPFGSGRRICPGMTMGTILVEM 452 Query: 344 IWTHLLRNFEFEL 306 +LL F++ L Sbjct: 453 ALLNLLYFFDWGL 465
>C71A9_SOYBN (O81970) Cytochrome P450 71A9 (EC 1.14.-.-) (P450 CP1)| Length = 499 Score = 52.8 bits (125), Expect = 1e-06 Identities = 37/125 (29%), Positives = 61/125 (48%) Frame = -2 Query: 680 LAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFANRL 501 L+++ + +KE LRLHPP +L+ + ++ K F+IP V + Sbjct: 346 LSKLLYIKSVVKEVLRLHPPAPLLVPREITENCTI----KGFEIPAKTRVLVNAKSIAMD 401 Query: 500 PHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRN 321 P ++NP+ + P+RF + K F + FG GR GC G FA ++ +LL Sbjct: 402 PCCWENPNEFLPERFLVSPIDFK-GQHFEMLPFGVGRRGCPGVNFAMPVVELALANLLFR 460 Query: 320 FEFEL 306 F++EL Sbjct: 461 FDWEL 465
>C4AE1_DROME (O46054) Cytochrome P450 4ae1 (EC 1.14.-.-) (CYPIVAE1)| Length = 496 Score = 52.8 bits (125), Expect = 1e-06 Identities = 37/121 (30%), Positives = 58/121 (47%) Frame = -2 Query: 677 AEMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFANRLP 498 A + L +KE+LRL+PP+ + R D + E IP G V R Sbjct: 352 ATLPYLSCVVKESLRLYPPIPAVARCLEKDLVID-----EGYIPVGTNVVVLLWQLLRDE 406 Query: 497 HIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNF 318 IF +P + P+R EE +SYI F G C+G+ FA L++K + T ++R++ Sbjct: 407 AIFTDPLVFQPERHLG--EEAPRLSPYSYIPFSAGPRNCIGQKFALLEMKTMVTKVIRHY 464 Query: 317 E 315 + Sbjct: 465 Q 465
>CP6D2_DROME (Q9W223) Probable cytochrome P450 6d2 (EC 1.14.-.-) (CYPVID2)| Length = 512 Score = 52.8 bits (125), Expect = 1e-06 Identities = 45/163 (27%), Positives = 71/163 (43%), Gaps = 3/163 (1%) Frame = -2 Query: 701 DKIDHDILAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATS 522 D+ ++ + ++ L CI E +R +P L L R+ D+ V G I KG + S Sbjct: 357 DRFTYEAVQDLKFLDICIMETIRKYPGLPFLNRECTEDYPVP---GTNHIIAKGTPILIS 413 Query: 521 PAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAI 342 R P F NP+ YDP RF + A +Y+ FG G C+ + K Sbjct: 414 LFGMQRDPVYFPNPNGYDPHRFDSNNMNYDQA---AYMPFGEGPRHCIALRMGKVNSKVA 470 Query: 341 WTHLLRNFEFELVSPFPENDWN---AMVVGIKGEVMVNYKRRK 222 +L NF+ + SP E ++ A V+ K + + +RK Sbjct: 471 VAKILANFDL-VQSPRKEVEFRFDAAPVLVTKEPLKLRLTKRK 512
>CP21A_CANFA (Q8WNW0) Cytochrome P450 21 (EC 1.14.99.10) (Cytochrome P450 XXI)| (Steroid 21-hydroxylase) (21-OHase) (P450-C21) (P-450c21) Length = 492 Score = 52.8 bits (125), Expect = 1e-06 Identities = 37/129 (28%), Positives = 61/129 (47%) Frame = -2 Query: 704 GDKIDHDILAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVAT 525 G +I + + +L + E LRL P ++ L H ++ G +DIP+G +V Sbjct: 329 GSRIPYRDPTRLPLLSATVAEVLRLRP--VVPLALPHCTTRPSSISG--YDIPEGMVVIP 384 Query: 524 SPAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKA 345 + A+ +++ P + PDRF +V ++FG G CLGEP A L++ Sbjct: 385 NLQGAHLDETVWERPQEFRPDRFLVPGASPRV------LAFGCGARVCLGEPLARLELLV 438 Query: 344 IWTHLLRNF 318 + LLR F Sbjct: 439 VLAQLLRAF 447
>C98A2_SOYBN (O48922) Cytochrome P450 98A2 (EC 1.14.-.-)| Length = 509 Score = 52.8 bits (125), Expect = 1e-06 Identities = 37/115 (32%), Positives = 58/115 (50%), Gaps = 2/115 (1%) Frame = -2 Query: 656 RCI-KEALRLHPPL-IMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFANRLPHIFKN 483 +C+ KEA+RLHPP +ML +++++ V +DIPKG V + R P ++K+ Sbjct: 352 QCVTKEAMRLHPPTPLMLPHRANANVKVGG-----YDIPKGSNVHVNVWAVARDPAVWKD 406 Query: 482 PDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNF 318 P + P+RF + D F + FG GR C G ++ HLL +F Sbjct: 407 PLEFRPERFLE-EDVDMKGHDFRLLPFGSGRRVCPGAQLGINLAASMLGHLLHHF 460
>CP134_DROME (Q9VG40) Probable cytochrome P450 313a4 (EC 1.14.-.-)| (CYPCCCXIIIA4) Length = 478 Score = 52.4 bits (124), Expect = 1e-06 Identities = 35/128 (27%), Positives = 63/128 (49%), Gaps = 1/128 (0%) Frame = -2 Query: 674 EMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFANRLPH 495 +M L + E++R+ PP+ ++ RQ+ D ++ +PKG +A +R Sbjct: 332 QMVYLDLILNESMRVIPPVPVVSRQTSQDLKLSNG----IVVPKGVQIAIDIYHMHRSKK 387 Query: 494 IF-KNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNF 318 I+ + ++++PD F +DK ++YI F G C+G +A + K LLRN+ Sbjct: 388 IWGPDAETFNPDHFLPHNIQDK--HPYAYIPFTKGIRNCIGWRYALISAKVTLAKLLRNY 445 Query: 317 EFELVSPF 294 F+ PF Sbjct: 446 RFKTSFPF 453
>C75A5_EUSGR (Q96418) Flavonoid 3',5'-hydroxylase (EC 1.14.13.88) (F3'5'H)| (Cytochrome P450 75A5) Length = 510 Score = 52.4 bits (124), Expect = 1e-06 Identities = 38/129 (29%), Positives = 60/129 (46%), Gaps = 2/129 (1%) Frame = -2 Query: 680 LAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFANRL 501 ++++ L KEA R HP + L + S E IPKG ++ + R Sbjct: 350 ISKLPYLQAICKEAFRKHPSTPLNLPRIASQAC----EVNGHYIPKGTRLSVNIWAIGRD 405 Query: 500 PHIFKNPDSYDPDRFAAGREE--DKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLL 327 P +++NP+ ++PDRF + D F I FG GR C G L ++ I L+ Sbjct: 406 PSLWENPNEFNPDRFLERKNAKIDPRGNDFELIPFGAGRRICAGTRLGILLVEYILGTLV 465 Query: 326 RNFEFELVS 300 +F++EL S Sbjct: 466 HSFDWELPS 474
>CP6G1_DROME (Q9V674) Cytochrome P450 6g1 (EC 1.14.-.-) (CYPVIG1) (Cyp6-like| protein) Length = 524 Score = 52.4 bits (124), Expect = 1e-06 Identities = 35/131 (26%), Positives = 60/131 (45%), Gaps = 3/131 (2%) Frame = -2 Query: 704 GDKIDHDILAEMDVLYRCIKEALRLHPPLIMLLRQSHS---DFSVTTREGKEFDIPKGHI 534 G + ++ + ++ L + E LR++P L L R+ S ++ + ++ + G Sbjct: 350 GGSLSYEKIQSLEYLAMVVDEVLRMYPVLPFLDREYESVEGQPDLSLKPFYDYTLENGTP 409 Query: 533 VATSPAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQ 354 V + P + NP +DP+RF+ ++ VA A Y FG G H C+G LQ Sbjct: 410 VFIPIYALHHDPKYWTNPSQFDPERFSPANRKNIVAMA--YQPFGSGPHNCIGSRIGLLQ 467 Query: 353 IKAIWTHLLRN 321 K LL+N Sbjct: 468 SKLGLVSLLKN 478
>C356_FUNHE (Q8AXY5) Cytochrome P450 3A56 (EC 1.14.14.1) (CYPIIIA56)| Length = 496 Score = 52.4 bits (124), Expect = 1e-06 Identities = 35/130 (26%), Positives = 61/130 (46%) Frame = -2 Query: 695 IDHDILAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPA 516 + + L EM+ L I E+LRL P L R + + + IPK +V Sbjct: 344 VHYQPLMEMEYLDCVINESLRLFPIAARLERVAKAAVEING-----IVIPKDMVVMIPTW 398 Query: 515 FANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWT 336 +R P I+ P+++ P+RF+ +++ + Y+ FG G C+G FA + IK Sbjct: 399 PLHRDPEIWPEPEAFKPERFSKKNKDN--IDPYIYMPFGSGPRNCIGMRFALVLIKLAVV 456 Query: 335 HLLRNFEFEL 306 +L+ + F + Sbjct: 457 EILQQYSFSV 466
>CP7A1_RABIT (P51542) Cytochrome P450 7A1 (EC 1.14.13.17) (Cholesterol| 7-alpha-monooxygenase) (CYPVII) (Cholesterol 7-alpha-hydroxylase) Length = 501 Score = 52.4 bits (124), Expect = 1e-06 Identities = 40/133 (30%), Positives = 62/133 (46%), Gaps = 7/133 (5%) Frame = -2 Query: 680 LAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFANRL 501 L +M VL IKE+LRL + + R + DF++ +G ++I K I+A P + Sbjct: 337 LNDMPVLDSIIKESLRLSSASLNI-RTAKEDFTLHLEDGS-YNIRKDDIIALYPQLMHLD 394 Query: 500 PHIFKNPDSYDPDRFAAGREEDKVAG-------AFSYISFGGGRHGCLGEPFAYLQIKAI 342 P I+ +P ++ DR+ + K + Y+ FG G C G FA +IK Sbjct: 395 PEIYPDPMTFKYDRYLDENRKTKTTFYSKGLKLKYYYMPFGSGATICPGRLFAIQEIKQF 454 Query: 341 WTHLLRNFEFELV 303 +L FE E V Sbjct: 455 LILMLSYFELEFV 467
>CP17A_SQUAC (Q92113) Cytochrome P450 17A1 (EC 1.14.99.9) (CYPXVII) (P450-C17)| (P450c17) (Steroid 17-alpha-hydroxylase/17,20 lyase) Length = 509 Score = 52.4 bits (124), Expect = 1e-06 Identities = 37/131 (28%), Positives = 64/131 (48%), Gaps = 1/131 (0%) Frame = -2 Query: 671 MDVLYRCIKEALRLHPPLIMLLRQ-SHSDFSVTTREGKEFDIPKGHIVATSPAFANRLPH 495 M+ L I E LR+ P +L+ + +D S+ ++ IPKG V + + Sbjct: 353 MNFLNATIHEILRIQPVSPLLIPHVALADSSIG-----DYTIPKGTRVIINLWAIHHDEK 407 Query: 494 IFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFE 315 +KNPD++DP RF + + + SY+ FG G CLGE A +++ + +L+ F Sbjct: 408 EWKNPDAFDPGRFLDEDGKYVCSSSESYLPFGAGTRVCLGEMLARMELFLFTSWILQRFT 467 Query: 314 FELVSPFPEND 282 ++ +P D Sbjct: 468 VQVPPGYPPPD 478
>C71B2_ARATH (O65788) Cytochrome P450 71B2 (EC 1.14.-.-)| Length = 502 Score = 52.4 bits (124), Expect = 1e-06 Identities = 35/133 (26%), Positives = 64/133 (48%), Gaps = 1/133 (0%) Frame = -2 Query: 701 DKIDHDILAEMDVLYRCIKEALRLHPPLIMLL-RQSHSDFSVTTREGKEFDIPKGHIVAT 525 ++I + L +++ L +KE RLHP L ++ R++ S + + +DIP + Sbjct: 343 ERITEEDLGKVEYLNHILKETFRLHPALPFVVPRETMSHIKI-----QGYDIPPKTQIQL 397 Query: 524 SPAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKA 345 + R P + +P+ ++P+RFA D F + FG GR C G P A ++ Sbjct: 398 NVWTIGRDPKRWNDPEEFNPERFA-NSSVDFRGQHFDLLPFGSGRRICPGMPMAIASVEL 456 Query: 344 IWTHLLRNFEFEL 306 +LL F++ + Sbjct: 457 ALMNLLYYFDWSM 469
>C11B2_MOUSE (P15539) Cytochrome P450 11B2, mitochondrial precursor (EC| 1.14.15.4) (EC 1.14.15.5) (CYPXIB2) (P450C11) (Steroid 11-beta-hydroxylase) (Aldosterone synthase) Length = 500 Score = 52.4 bits (124), Expect = 1e-06 Identities = 33/124 (26%), Positives = 60/124 (48%) Frame = -2 Query: 680 LAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFANRL 501 ++++ +L +KE LRL+P L R SD + + + +P G +V R Sbjct: 359 MSDLPLLKAALKETLRLYPVGGFLGRILSSDLVL-----QNYHVPAGTLVLLYLYSMGRN 413 Query: 500 PHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRN 321 P +F P+ Y P R+ + +F +++FG G CLG A +++ + H+L+ Sbjct: 414 PAVFPRPERYMPQRWLERKR------SFQHLAFGFGVRQCLGRRLAEVEMMLLLHHILKT 467 Query: 320 FEFE 309 F+ E Sbjct: 468 FQVE 471 Database: uniprot_sprot.fasta Posted date: May 25, 2006 5:36 PM Number of letters in database: 80,573,946 Number of sequences in database: 219,361 Lambda K H 0.318 0.135 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 101,783,921 Number of Sequences: 219361 Number of extensions: 2130512 Number of successful extensions: 7581 Number of sequences better than 10.0: 500 Number of HSP's better than 10.0 without gapping: 6710 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 7009 length of database: 80,573,946 effective HSP length: 109 effective length of database: 56,663,597 effective search space used: 7196276819 frameshift window, decay const: 50, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
