>LRP10_HUMAN (Q7Z4F1) Low-density lipoprotein receptor-related protein 10|
           precursor
          Length = 713

 Score = 34.7 bits (78), Expect = 0.24
 Identities = 35/111 (31%), Positives = 44/111 (39%), Gaps = 14/111 (12%)
 Frame = -3

Query: 424 LINRTGLPVLHTELRFVMEPSGS--------------GAAEPGEDGRDQEPAHERSYAPS 287
           L+ RT  P   +E R  + PS +              G A  G+DG    P   ++  PS
Sbjct: 565 LLPRTNTPARASEARSQVTPSAAPLEALDGGTGPAREGGAVGGQDGEQAPPLPIKAPLPS 624

Query: 286 NGAGPAVAETREAPNSSGLECVPQRFFVSSCVVQLAARGRGDA*EGTGPPG 134
               PA     EAP    L  +P    + S VVQ A RGR       GPPG
Sbjct: 625 ASTSPAPTTVPEAPGP--LPSLPLEPSLLSGVVQ-ALRGR--LLPSLGPPG 670

>PAK4_MOUSE (Q8BTW9) Serine/threonine-protein kinase PAK 4 (EC 2.7.11.1)|
           (p21-activated kinase 4) (PAK-4)
          Length = 593

 Score = 34.3 bits (77), Expect = 0.31
 Identities = 40/138 (28%), Positives = 54/138 (39%), Gaps = 16/138 (11%)
 Frame = -3

Query: 595 GAGSGDRFRLPVQRAPRQ----PAHP-----------GPSPSIGSVPLLQTTTEQTTGRF 461
           G+GSGDR R+  ++ P+     P  P           GP  S      L + T+   GR 
Sbjct: 145 GSGSGDRRRVGPEKRPKSSRDGPGGPQEASRDKRPLSGPDVSTPQPGSLTSGTKLAAGRP 204

Query: 460 FQTN*LSEV*RELINRTGLPVLHTELRFVMEPSGSGAAEPGEDGRDQEPAHERSYAPSNG 281
           F T   ++         G P  HT       PS +G A P      + P   R  APS G
Sbjct: 205 FNTYPRADTDHPPRGAQGEP--HT--MAPNGPSATGLAAPQSSSSSRPPTRARG-APSPG 259

Query: 280 A-GPAVAETREAPNSSGL 230
             GP  +E + AP +  L
Sbjct: 260 VLGPHASEPQLAPPARAL 277

>EI2BD_SCHPO (Q09924) Probable translation initiation factor eIF-2B delta|
           subunit (eIF-2B GDP-GTP exchange factor)
          Length = 467

 Score = 33.9 bits (76), Expect = 0.41
 Identities = 24/85 (28%), Positives = 37/85 (43%)
 Frame = -3

Query: 361 GSGAAEPGEDGRDQEPAHERSYAPSNGAGPAVAETREAPNSSGLECVPQRFFVSSCVVQL 182
           G  A +  +DG+DQ P  E S     G  PA A +  +PN   L     +  +     Q 
Sbjct: 2   GFSAEQAKKDGKDQSPVSESSSV--GGTSPATASSVVSPNEPKLSGKEAK-ALKKARKQA 58

Query: 181 AARGRGDA*EGTGPPGLRKLKCEAL 107
           + R + +A     PPG+ + K  A+
Sbjct: 59  SRRAKAEAAAANNPPGVSEEKKVAI 83

>UBP5_HUMAN (P45974) Ubiquitin carboxyl-terminal hydrolase 5 (EC 3.1.2.15)|
           (Ubiquitin thioesterase 5)
           (Ubiquitin-specific-processing protease 5)
           (Deubiquitinating enzyme 5) (Isopeptidase T)
          Length = 858

 Score = 32.7 bits (73), Expect = 0.91
 Identities = 18/58 (31%), Positives = 26/58 (44%)
 Frame = +1

Query: 121 STFLGLEVPFLPMHRLSREQRVELRKRKQRNAEERTPVQTSWAPPLSPPPRVRLHWRG 294
           +TFLG    ++  H     QRV L  R+ R  +E  P   +  PP   P R+ +   G
Sbjct: 48  NTFLGFGKQYVERHFNKTGQRVYLHLRRTRRPKEEDPATGTGDPPRKKPTRLAIGVEG 105

>FBX38_MOUSE (Q8BMI0) F-box only protein 38 (Modulator of KLF7 activity) (MoKA)|
          Length = 1194

 Score = 25.8 bits (55), Expect(2) = 2.6
 Identities = 20/67 (29%), Positives = 25/67 (37%), Gaps = 12/67 (17%)
 Frame = +2

Query: 461 ESPCCLLCCCL--QERNRTNG----------G*RTWVSGLSWGPLDWKPETIPRARSQSP 604
           ES  C  CCCL  QE  R  G               V+G       +   T+P+  S  P
Sbjct: 775 ESSVCPRCCCLRPQESQRRTGRCSDEERPSTSRACVVNGADGTRSAFSFRTLPQGGSSGP 834

Query: 605 PHPTRTS 625
            H  RT+
Sbjct: 835 AHDERTN 841



 Score = 23.9 bits (50), Expect(2) = 2.6
 Identities = 20/69 (28%), Positives = 30/69 (43%), Gaps = 1/69 (1%)
 Frame = +3

Query: 201 ETKKR*GTHSSPDELGASLVSATAGPAPLEGA*ERSWAGSWSRP-SSPGSAAPEPDGSIT 377
           E KK    + S     +S  ++TAG A        S +  ++R  +S GS+ P P     
Sbjct: 695 EKKKSKDVYPSCSSSSSSTAASTAGNASSPST--ASQSPDFARTVTSSGSSEPSPPEVDV 752

Query: 378 NRNSVCRTG 404
           +R  VC  G
Sbjct: 753 SRQCVCSPG 761

>TRFL_CAMDR (Q9TUM0) Lactotransferrin precursor (EC 3.4.21.-) (Lactoferrin)|
          Length = 708

 Score = 31.2 bits (69), Expect = 2.6
 Identities = 15/37 (40%), Positives = 26/37 (70%), Gaps = 2/37 (5%)
 Frame = -3

Query: 283 GAGPAVAETREAPNSSGLECV--PQRFFVSSCVVQLA 179
           G  P +AE++++P SSGL+CV  P + +++  VV+ A
Sbjct: 425 GLVPVLAESQQSPESSGLDCVHRPVKGYLAVAVVRKA 461

>GCFC_HUMAN (Q9Y5B6) GC-rich sequence DNA-binding factor homolog|
          Length = 917

 Score = 30.8 bits (68), Expect = 3.5
 Identities = 14/33 (42%), Positives = 18/33 (54%)
 Frame = +1

Query: 172 REQRVELRKRKQRNAEERTPVQTSWAPPLSPPP 270
           + +RV +RKR     EER   +    PPL PPP
Sbjct: 4   KARRVNVRKRNDSEEEERERDEEQEPPPLLPPP 36

>RL15_PYRFU (Q8U018) 50S ribosomal protein L15P|
          Length = 147

 Score = 30.8 bits (68), Expect = 3.5
 Identities = 20/68 (29%), Positives = 33/68 (48%), Gaps = 2/68 (2%)
 Frame = -2

Query: 272 RGGGDKGGAQLVWTGVRSSAFLCFLLXXXXXXXXXXXCIGRNGTSRPKKV--EVRSLEAN 99
           RGGG KGG  +  TG R+ +   + +            +G+ G SRP +V  EVR +   
Sbjct: 26  RGGGSKGGRGMAGTGKRNKSKWTWTI------KYAPDHLGKRGFSRPPEVQREVRVVNLK 79

Query: 98  CVKQYLSK 75
            + ++L +
Sbjct: 80  FIDEHLDE 87

>ENV2_MOUSE (P11370) Retrovirus-related Env polyprotein from Fv-4 locus|
          Length = 679

 Score = 30.8 bits (68), Expect = 3.5
 Identities = 17/44 (38%), Positives = 26/44 (59%), Gaps = 6/44 (13%)
 Frame = +1

Query: 484 LLFAGEEPN-----QWRVTDLGERVVLGPSGLEAGNDPPS-PLP 597
           L  +G +P      + R+TDLG RV +GP+ + +   PPS P+P
Sbjct: 242 LYISGHDPGLTFGIRLRITDLGPRVPIGPNPVLSDQRPPSRPVP 285

>FOXC1_HUMAN (Q12948) Forkhead box protein C1 (Forkhead-related protein FKHL7)|
           (Forkhead-related transcription factor 3) (FREAC-3)
          Length = 553

 Score = 30.8 bits (68), Expect = 3.5
 Identities = 18/47 (38%), Positives = 23/47 (48%)
 Frame = +3

Query: 231 SPDELGASLVSATAGPAPLEGA*ERSWAGSWSRPSSPGSAAPEPDGS 371
           SPD   +SL S ++ P  L  A   S  G+ S P  P  +AP P  S
Sbjct: 259 SPDSSSSSLSSGSSPPGSLPSARPLSLDGADSAPPPPAPSAPPPHHS 305

>KDSA_BRAJA (Q89KV0) 2-dehydro-3-deoxyphosphooctonate aldolase (EC 2.5.1.55)|
           (Phospho-2-dehydro-3-deoxyoctonate aldolase)
           (3-deoxy-D-manno-octulosonic acid 8-phosphate
           synthetase) (KDO-8-phosphate synthetase) (KDO 8-P
           synthase) (KDOPS)
          Length = 282

 Score = 30.4 bits (67), Expect = 4.5
 Identities = 25/76 (32%), Positives = 33/76 (43%), Gaps = 3/76 (3%)
 Frame = -3

Query: 424 LINRTGLPVLHTELRFVMEPSGSGAAEPGEDGRDQEPAHERSYAPSNGAGPAVAETREAP 245
           L   TG PV+      V +P G G +  GE  R+  P   R+ A + G      ET   P
Sbjct: 192 LARTTGAPVIFDATHSVQQPGGKGTSSGGE--REFVPVLARA-AVAVGVAGVFIETHPDP 248

Query: 244 NSS---GLECVPQRFF 206
           +S+   G   VP R F
Sbjct: 249 DSAPSDGPNMVPLREF 264

>TAF5_MOUSE (Q8C092) Transcription initiation factor TFIID subunit 5|
           (Transcription initiation factor TFIID 100 kDa subunit)
           (TAF(II)100) (TAFII-100) (TAFII100)
          Length = 801

 Score = 30.4 bits (67), Expect = 4.5
 Identities = 19/47 (40%), Positives = 26/47 (55%), Gaps = 2/47 (4%)
 Frame = +3

Query: 258 VSATAGPAPLEGA*ERSWAGSWSR--PSSPGSAAPEPDGSITNRNSV 392
           V+ +  P  L+GA   + +   SR   S PGSAAPEP G+  +  SV
Sbjct: 128 VAGSGAPGELDGAGAEAASALLSRVTASVPGSAAPEPPGTGASVTSV 174

>RL15_PYRAB (Q9V1V7) 50S ribosomal protein L15P|
          Length = 147

 Score = 30.4 bits (67), Expect = 4.5
 Identities = 20/68 (29%), Positives = 33/68 (48%), Gaps = 2/68 (2%)
 Frame = -2

Query: 272 RGGGDKGGAQLVWTGVRSSAFLCFLLXXXXXXXXXXXCIGRNGTSRPKKV--EVRSLEAN 99
           RGGG KGG  +  TG R+ +   + +            +G+ G SRP +V  EVR++   
Sbjct: 26  RGGGSKGGRGMAGTGKRNKSKWTWTI------KYAPDHLGKRGFSRPPEVQREVRTVTLK 79

Query: 98  CVKQYLSK 75
            + + L +
Sbjct: 80  SIDENLDE 87

>RUSC2_MOUSE (Q80U22) RUN and SH3 domain-containing protein 2|
          Length = 1514

 Score = 30.4 bits (67), Expect = 4.5
 Identities = 15/48 (31%), Positives = 23/48 (47%)
 Frame = -3

Query: 379 FVMEPSGSGAAEPGEDGRDQEPAHERSYAPSNGAGPAVAETREAPNSS 236
           F  + SG GA   G +     P+   SY+P   AGP  + T  + ++S
Sbjct: 748 FTSQASGRGARNAGPEPETSRPSPLGSYSPVRSAGPFGSSTDSSASTS 795

>DPCA2_HUMAN (Q86SG4) Dresden prostate carcinoma 2 protein (D-PCa-2)|
          Length = 172

 Score = 30.0 bits (66), Expect = 5.9
 Identities = 16/49 (32%), Positives = 26/49 (53%), Gaps = 9/49 (18%)
 Frame = +1

Query: 175 EQRVELRKRKQRNAEE---------RTPVQTSWAPPLSPPPRVRLHWRG 294
           ++R+E+ K +Q   EE         R P+ +++ PPLS PP  R   +G
Sbjct: 30  QKRIEMHKAEQCEEEEAMTPRPTKARAPLPSAYVPPLSLPPCPRERLKG 78

>ENV_MLVCB (P08360) Env polyprotein precursor (Coat polyprotein) [Contains:|
           Coat protein GP70; Spike protein p15E; R protein]
          Length = 661

 Score = 30.0 bits (66), Expect = 5.9
 Identities = 17/44 (38%), Positives = 26/44 (59%), Gaps = 6/44 (13%)
 Frame = +1

Query: 484 LLFAGEEPN-----QWRVTDLGERVVLGPSGLEAGNDPPS-PLP 597
           L  +G +P      + +VTDLG RV +GP+ + +   PPS P+P
Sbjct: 242 LYISGHDPGLTFGIRLKVTDLGPRVPIGPNPVLSDQRPPSRPVP 285

>ZP1_HUMAN (P60852) Zona pellucida sperm-binding protein 1 precursor (Zona|
           pellucida glycoprotein 1) (Zp-1)
          Length = 638

 Score = 30.0 bits (66), Expect = 5.9
 Identities = 15/46 (32%), Positives = 23/46 (50%)
 Frame = +1

Query: 133 GLEVPFLPMHRLSREQRVELRKRKQRNAEERTPVQTSWAPPLSPPP 270
           G+ +   P   ++R+   +L  R   NA +  P+Q S  PP SP P
Sbjct: 353 GIHIQKGPQGSITRDSTFQLHVRCVFNASDFLPIQASIFPPPSPAP 398

>KDSA_RHOPA (P61657) 2-dehydro-3-deoxyphosphooctonate aldolase (EC 2.5.1.55)|
           (Phospho-2-dehydro-3-deoxyoctonate aldolase)
           (3-deoxy-D-manno-octulosonic acid 8-phosphate
           synthetase) (KDO-8-phosphate synthetase) (KDO 8-P
           synthase) (KDOPS)
          Length = 287

 Score = 30.0 bits (66), Expect = 5.9
 Identities = 24/72 (33%), Positives = 31/72 (43%), Gaps = 3/72 (4%)
 Frame = -3

Query: 412 TGLPVLHTELRFVMEPSGSGAAEPGEDGRDQEPAHERSYAPSNGAGPAVAETREAPN--- 242
           TG PV+      V +P G G +  GE  R+  P   R+ A + G      ET   P+   
Sbjct: 196 TGAPVIFDATHSVQQPGGKGTSSGGE--REYVPVLARA-AVAVGVAGVFIETHPDPDHAP 252

Query: 241 SSGLECVPQRFF 206
           S G   VP R F
Sbjct: 253 SDGPNMVPLREF 264

>PIRK5_CHICK (Q5ZIB8) Phosphoinositide 3-kinase regulatory subunit 5 (PI3-kinase|
           regulatory subunit 5)
          Length = 881

 Score = 30.0 bits (66), Expect = 5.9
 Identities = 29/94 (30%), Positives = 41/94 (43%), Gaps = 7/94 (7%)
 Frame = -3

Query: 574 FRLPVQRAPRQPA----HPGPSPSIGSVPLLQTTTEQTTGRFFQTN*LSEV*REL---IN 416
           F +PV+R+   PA    HP PSPS   +  L        G    TN +S     L     
Sbjct: 565 FYVPVKRSCLLPAALLMHPPPSPSDLQLRALAQAEPTLAGAESSTNDISHYIGMLDPWYE 624

Query: 415 RTGLPVLHTELRFVMEPSGSGAAEPGEDGRDQEP 314
           R  L +++  +  + + S    AEP ED R+Q P
Sbjct: 625 RNVLGLMNLPMDVLCQ-SAKPEAEPQEDSREQLP 657

>LRP10_MOUSE (Q7TQH7) Low-density lipoprotein receptor-related protein 10|
           precursor
          Length = 713

 Score = 29.6 bits (65), Expect = 7.7
 Identities = 30/99 (30%), Positives = 39/99 (39%), Gaps = 13/99 (13%)
 Frame = -3

Query: 424 LINRTGLPVLHTELRFVMEPSG-------------SGAAEPGEDGRDQEPAHERSYAPSN 284
           L+ RT  P    E R  + PS               G A  G+DG    P   ++  P+ 
Sbjct: 566 LLPRTNTPARAPETRSQVTPSVPSEALDDSTGQACEGGAVGGQDGEQAPPLPIKTPIPTP 625

Query: 283 GAGPAVAETREAPNSSGLECVPQRFFVSSCVVQLAARGR 167
              PA+A   E P    L  VP    + S VVQ+  RGR
Sbjct: 626 STLPALATVSEPPGP--LPSVPVESSLLSGVVQV-LRGR 661

>PKNH_MYCTU (Q11053) Probable serine/threonine-protein kinase pknH (EC|
           2.7.11.1)
          Length = 626

 Score = 29.6 bits (65), Expect = 7.7
 Identities = 16/49 (32%), Positives = 26/49 (53%)
 Frame = -3

Query: 403 PVLHTELRFVMEPSGSGAAEPGEDGRDQEPAHERSYAPSNGAGPAVAET 257
           PV    ++   +PS +  A+PG  G+   P  + S+AP++G  PA   T
Sbjct: 322 PVTPPGVQPAPKPSYTPPAQPGPAGQRPGPTGQPSWAPNSGPMPASGPT 370

>DOT1L_HUMAN (Q8TEK3) Histone-lysine N-methyltransferase, H3 lysine-79 specific|
            (EC 2.1.1.43) (Histone H3-K79 methyltransferase)
            (H3-K79-HMTase) (DOT1-like protein)
          Length = 1739

 Score = 29.6 bits (65), Expect = 7.7
 Identities = 17/39 (43%), Positives = 23/39 (58%)
 Frame = +3

Query: 246  GASLVSATAGPAPLEGA*ERSWAGSWSRPSSPGSAAPEP 362
            GA+  SAT GP+PL+ A   S A S+  P+S  +  P P
Sbjct: 1558 GAACGSATLGPSPLQAAASAS-ASSFQAPASVETRPPPP 1595

>SLA1_YEAST (P32790) Cytoskeleton assembly control protein SLA1|
          Length = 1244

 Score = 29.6 bits (65), Expect = 7.7
 Identities = 13/35 (37%), Positives = 20/35 (57%)
 Frame = +1

Query: 163 RLSREQRVELRKRKQRNAEERTPVQTSWAPPLSPP 267
           RL   +  EL+K ++   EER+ +Q    PP+ PP
Sbjct: 592 RLKERELYELKKARELLDEERSRLQEKELPPIKPP 626

>HCN2_RAT (Q9JKA9) Potassium/sodium hyperpolarization-activated cyclic|
           nucleotide-gated channel 2
          Length = 863

 Score = 29.6 bits (65), Expect = 7.7
 Identities = 26/80 (32%), Positives = 34/80 (42%), Gaps = 1/80 (1%)
 Frame = +3

Query: 135 PGGPVPSYASPLPRAAS*TTQEETKKR*GTHSSPDELGASLVSATAGPAPLEGA*ERSWA 314
           P GP+P  ASP P AAS      + +     +SP  +  S  +      P       S  
Sbjct: 734 PPGPLPPAASPGPPAASPPAAPSSPR--APRTSPYGVPGSPATRVGPALPARRLSRASRP 791

Query: 315 GSWSRPSSP-GSAAPEPDGS 371
            S S+PS P G+ AP P  S
Sbjct: 792 LSASQPSLPHGAPAPSPAAS 811


  Database: uniprot_sprot.fasta
    Posted date:  May 25, 2006  5:36 PM
  Number of letters in database: 80,573,946
  Number of sequences in database:  219,361
  
Lambda     K      H
   0.318    0.135    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 99,773,274
Number of Sequences: 219361
Number of extensions: 2304774
Number of successful extensions: 10622
Number of sequences better than 10.0: 24
Number of HSP's better than 10.0 without gapping: 9242
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 10594
length of database: 80,573,946
effective HSP length: 107
effective length of database: 57,102,319
effective search space used: 5824436538
frameshift window, decay const: 50,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)