ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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更新日:2016年5月1日

Clone Information

BLAST Search Result

Clone Name rbasd18d12
Clone Library Name barley_pub

No. Definition Score
(bits)
E
Value
1KPYC_TOBAC (Q42954) Pyruvate kinase, cytosolic isozyme (EC 2.7.1... 120 4e-27
2KPYC_SOLTU (P22200) Pyruvate kinase, cytosolic isozyme (EC 2.7.1... 115 9e-26
3KPYC_SOYBN (Q42806) Pyruvate kinase, cytosolic isozyme (EC 2.7.1... 111 2e-24
4KPYC_ARATH (O65595) Probable pyruvate kinase, cytosolic isozyme ... 105 1e-22
5KPYK_EMENI (P22360) Pyruvate kinase (EC 2.7.1.40) (PK) 64 4e-10
6KPYK_ASPNG (Q12669) Pyruvate kinase (EC 2.7.1.40) (PK) 64 5e-10
7KPYK_NEUCR (Q7RVA8) Pyruvate kinase (EC 2.7.1.40) (PK) 63 9e-10
8KPYK_XENLA (Q92122) Pyruvate kinase muscle isozyme (EC 2.7.1.40)... 62 1e-09
9KPYK_YARLI (P30614) Pyruvate kinase (EC 2.7.1.40) (PK) 60 5e-09
10KPYK_CHICK (P00548) Pyruvate kinase muscle isozyme (EC 2.7.1.40) 60 6e-09
11KPYK2_CANGA (Q6FV12) Pyruvate kinase 2 (EC 2.7.1.40) (PK 2) 60 6e-09
12KPYK1_CANGA (Q6FIS9) Pyruvate kinase 1 (EC 2.7.1.40) (PK 1) 59 1e-08
13KPYK_TRIRE (P31865) Pyruvate kinase (EC 2.7.1.40) (PK) 59 1e-08
14KPYK1_YEAST (P00549) Pyruvate kinase 1 (EC 2.7.1.40) (PK 1) 59 2e-08
15KPYM_RAT (P11980) Pyruvate kinase isozymes M1/M2 (EC 2.7.1.40) (... 57 4e-08
16KPYM_PONPY (Q5NVN0) Pyruvate kinase isozyme M1 (EC 2.7.1.40) 57 4e-08
17KPYK_SACKL (Q875S4) Pyruvate kinase (EC 2.7.1.40) (PK) 57 4e-08
18KPYM_RABIT (P11974) Pyruvate kinase isozymes M1/M2 (EC 2.7.1.40)... 57 5e-08
19KPYM_FELCA (P11979) Pyruvate kinase isozyme M1 (EC 2.7.1.40) (Py... 57 5e-08
20KPYK_DROME (O62619) Pyruvate kinase (EC 2.7.1.40) (PK) 57 5e-08
21KPYK2_TRYBB (P30616) Pyruvate kinase 2 (EC 2.7.1.40) (PK 2) 56 1e-07
22KPYK1_TRYBB (P30615) Pyruvate kinase 1 (EC 2.7.1.40) (PK 1) 56 1e-07
23KPYM_MOUSE (P52480) Pyruvate kinase isozyme M2 (EC 2.7.1.40) 55 2e-07
24KPYM_HUMAN (P14618) Pyruvate kinase isozymes M1/M2 (EC 2.7.1.40)... 55 2e-07
25KPYK_EIMTE (O44006) Pyruvate kinase (EC 2.7.1.40) (PK) 55 2e-07
26KPYK_KLULA (Q875M9) Pyruvate kinase (EC 2.7.1.40) (PK) 55 2e-07
27KPYK_SACCA (Q875Z9) Pyruvate kinase (EC 2.7.1.40) (PK) 55 3e-07
28KPYK_ASHGO (Q759A9) Pyruvate kinase (EC 2.7.1.40) (PK) 55 3e-07
29KPYK_BACSU (P80885) Pyruvate kinase (EC 2.7.1.40) (PK) (Vegetati... 54 4e-07
30KPYK2_YEAST (P52489) Pyruvate kinase 2 (EC 2.7.1.40) (PK 2) 54 6e-07
31KPYR_HUMAN (P30613) Pyruvate kinase isozymes R/L (EC 2.7.1.40) (... 53 7e-07
32KPYR_MOUSE (P53657) Pyruvate kinase isozymes R/L (EC 2.7.1.40) (... 52 2e-06
33KPYR_CANFA (Q29536) Pyruvate kinase isozyme R (EC 2.7.1.40) (Fra... 51 3e-06
34KPYR_RAT (P12928) Pyruvate kinase isozymes R/L (EC 2.7.1.40) (L-PK) 51 4e-06
35KPYK_TRYBO (Q27788) Pyruvate kinase (EC 2.7.1.40) (PK) 50 5e-06
36KPYK_SCHPO (Q10208) Pyruvate kinase (EC 2.7.1.40) (PK) 50 6e-06
37KPYK_LEIME (Q27686) Pyruvate kinase (EC 2.7.1.40) (PK) 50 8e-06
38KPYK_LACDE (P34038) Pyruvate kinase (EC 2.7.1.40) (PK) 49 1e-05
39KPYK_BACST (Q02499) Pyruvate kinase (EC 2.7.1.40) (PK) 49 2e-05
40KPYK_DEBHA (Q6BS75) Pyruvate kinase (EC 2.7.1.40) (PK) 48 2e-05
41KPYK_CHLMU (Q9PK61) Pyruvate kinase (EC 2.7.1.40) (PK) 48 2e-05
42KPYK_CHLTR (P94685) Pyruvate kinase (EC 2.7.1.40) (PK) 45 3e-04
43KPYK_AGABI (O94122) Pyruvate kinase (EC 2.7.1.40) (PK) 45 3e-04
44KPYK_BACPY (P51182) Pyruvate kinase (EC 2.7.1.40) (PK) 44 5e-04
45KPYK_LACLA (Q07637) Pyruvate kinase (EC 2.7.1.40) (PK) 44 5e-04
46KPYK_CLOAB (O08309) Pyruvate kinase (EC 2.7.1.40) (PK) 42 0.001
47KPYK_CHLPN (Q9Z984) Pyruvate kinase (EC 2.7.1.40) (PK) 40 0.007
48KPYK2_AGRVI (Q44473) Pyruvate kinase (EC 2.7.1.40) (PK) 38 0.032
49KPYK_CLOPE (Q46289) Pyruvate kinase (EC 2.7.1.40) (PK) 37 0.042
50KPYK2_SYNY3 (P73534) Pyruvate kinase 2 (EC 2.7.1.40) (PK 2) 37 0.055
51LAMA1_HUMAN (P25391) Laminin alpha-1 chain precursor (Laminin A ... 33 0.80
52FTHS_LACJO (Q74JC1) Formate--tetrahydrofolate ligase (EC 6.3.4.3... 31 4.0
53ORYB_ORYSA (P25777) Oryzain beta chain precursor (EC 3.4.22.-) 31 4.0
54KPYK2_ECOLI (P21599) Pyruvate kinase II (EC 2.7.1.40) (PK-2) 30 8.8
55CRCB_XANAC (Q8PKZ5) Protein crcB homolog 30 8.8
56RELB_XENLA (P51510) Transcription factor RelB homolog 30 8.8

>KPYC_TOBAC (Q42954) Pyruvate kinase, cytosolic isozyme (EC 2.7.1.40) (PK)|
          Length = 508

 Score =  120 bits (301), Expect = 4e-27
 Identities = 66/144 (45%), Positives = 88/144 (61%)
 Frame = -2

Query: 656 FKRTVKYVGEPMTHLESIASSAVRAAIKVKASVIICFTSSGRAARLIAKYRPTMPVLSVV 477
           FKR +     PM+ LES+ASSAVR A   KA++I+  T  G  A+L+AKYRP MP+LSVV
Sbjct: 363 FKRIMSNAPVPMSPLESLASSAVRTANSAKAALILVLTRGGSTAKLVAKYRPGMPILSVV 422

Query: 476 IPRLKTNQLKWSFTGAFEARQSLIVRGLFPMLADPRHPAESTSTTNESVLKVALDHGKAS 297
           +P +KT+   W+ +    AR SLI RGL P+L      A    +T E+ L  AL H K  
Sbjct: 423 VPEIKTDSFDWTCSDESPARHSLIFRGLVPVLHAGSARASHEESTEEA-LDFALQHAKTK 481

Query: 296 GVIKSHDRVVVCQKVGDSSVVKII 225
           G+ K  D VV   +VG +SV+KI+
Sbjct: 482 GLCKQGDSVVALHRVGTASVIKIV 505



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>KPYC_SOLTU (P22200) Pyruvate kinase, cytosolic isozyme (EC 2.7.1.40) (PK)|
          Length = 510

 Score =  115 bits (289), Expect = 9e-26
 Identities = 61/148 (41%), Positives = 89/148 (60%)
 Frame = -2

Query: 671 NQDLYFKRTVKYVGEPMTHLESIASSAVRAAIKVKASVIICFTSSGRAARLIAKYRPTMP 492
           + +  FK  ++    PM+ LES+ASSAVR A K +A +I+  T  G  A+L+AKYRP +P
Sbjct: 360 DNEAIFKEMIRCTPLPMSPLESLASSAVRTANKARAKLIVVLTRGGSTAKLVAKYRPAVP 419

Query: 491 VLSVVIPRLKTNQLKWSFTGAFEARQSLIVRGLFPMLADPRHPAESTSTTNESVLKVALD 312
           +LSVV+P L T+   WS +    AR SL+ RGL P+L +    A  + +T E +L+ AL 
Sbjct: 420 ILSVVVPVLTTDSFDWSISDETPARHSLVYRGLIPLLGEGSAKATDSEST-EVILEAALK 478

Query: 311 HGKASGVIKSHDRVVVCQKVGDSSVVKI 228
                G+ K  D VV   ++G +SV+KI
Sbjct: 479 SAVTRGLCKPGDAVVALHRIGSASVIKI 506



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>KPYC_SOYBN (Q42806) Pyruvate kinase, cytosolic isozyme (EC 2.7.1.40) (PK)|
          Length = 511

 Score =  111 bits (278), Expect = 2e-24
 Identities = 61/143 (42%), Positives = 85/143 (59%)
 Frame = -2

Query: 656 FKRTVKYVGEPMTHLESIASSAVRAAIKVKASVIICFTSSGRAARLIAKYRPTMPVLSVV 477
           FK  ++    PM+ LES+ASSAVR A K KA +I+  T  G  A+L+AKYRP +P+LSVV
Sbjct: 366 FKEMIRSTPLPMSPLESLASSAVRTANKAKAKLIVVLTRGGSTAKLVAKYRPAVPILSVV 425

Query: 476 IPRLKTNQLKWSFTGAFEARQSLIVRGLFPMLADPRHPAESTSTTNESVLKVALDHGKAS 297
           +P L T+   W+ +    AR SLI RGL P+L +    A    +T E +L+ AL      
Sbjct: 426 VPVLSTDSFDWTCSDETPARHSLIYRGLIPILGEGSAKATDAEST-EVILEAALKSATER 484

Query: 296 GVIKSHDRVVVCQKVGDSSVVKI 228
            + K  D VV   ++G +SV+KI
Sbjct: 485 ALCKPGDAVVALHRIGAASVIKI 507



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>KPYC_ARATH (O65595) Probable pyruvate kinase, cytosolic isozyme (EC 2.7.1.40)|
           (PK)
          Length = 497

 Score =  105 bits (263), Expect = 1e-22
 Identities = 57/144 (39%), Positives = 89/144 (61%)
 Frame = -2

Query: 656 FKRTVKYVGEPMTHLESIASSAVRAAIKVKASVIICFTSSGRAARLIAKYRPTMPVLSVV 477
           FKR + +   PM+ +ES+ASSAVR A   +A++++  T  G  ARL+AKYRP +P+LSVV
Sbjct: 352 FKRIMLHAAVPMSPMESLASSAVRTATSSRATLMMVLTRGGSTARLVAKYRPGIPILSVV 411

Query: 476 IPRLKTNQLKWSFTGAFEARQSLIVRGLFPMLADPRHPAESTSTTNESVLKVALDHGKAS 297
           +P + ++   W+ +    AR SLI RGL P+L      A    +T E+ L+ A ++GK  
Sbjct: 412 VPEITSDSFDWACSNEAPARHSLIYRGLVPVLYAGSARASIDESTEET-LEFASEYGKKK 470

Query: 296 GVIKSHDRVVVCQKVGDSSVVKII 225
            + K+ D VV   + G++ V+KI+
Sbjct: 471 QLCKTGDSVVALFRTGNAIVIKIL 494



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>KPYK_EMENI (P22360) Pyruvate kinase (EC 2.7.1.40) (PK)|
          Length = 526

 Score = 63.9 bits (154), Expect = 4e-10
 Identities = 42/145 (28%), Positives = 71/145 (48%), Gaps = 7/145 (4%)
 Frame = -2

Query: 626 PMTHLESIASSAVRAAIKVKASVIICFTSSGRAARLIAKYRPTMPVLSVVIPRLKTNQLK 447
           P   +ESIA +AV A++++ A  I+  T+SG  AR+I+KYRP  P++ V      T    
Sbjct: 389 PTDTVESIAMAAVSASLELNAGAIVVLTTSGNTARMISKYRPVCPIIMVSRNPAAT---- 444

Query: 446 WSFTGAFEARQSLIVRGLFPMLADPRHPAESTSTTNESV---LKVALDHGKASGVIKSHD 276
                    R S + RG++P     + P  +     E V   LK  ++HG   G+I   D
Sbjct: 445 ---------RYSHLYRGVWPFYFPEKKPDFNVKIWQEDVDRRLKWGINHGLKLGIINKGD 495

Query: 275 RVVVCQ----KVGDSSVVKIIELDD 213
            +V  Q     +G ++ V+++  ++
Sbjct: 496 NIVCVQGWRGGMGHTNTVRVVPAEE 520



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>KPYK_ASPNG (Q12669) Pyruvate kinase (EC 2.7.1.40) (PK)|
          Length = 526

 Score = 63.5 bits (153), Expect = 5e-10
 Identities = 42/150 (28%), Positives = 73/150 (48%), Gaps = 7/150 (4%)
 Frame = -2

Query: 626 PMTHLESIASSAVRAAIKVKASVIICFTSSGRAARLIAKYRPTMPVLSVVIPRLKTNQLK 447
           P   +ESIA +AV A++++ A  I+  T+SG+ AR ++KYRP  P++ V           
Sbjct: 389 PTDTVESIAMAAVSASLELNAGAIVVLTTSGKTARYLSKYRPVCPIVMVT---------- 438

Query: 446 WSFTGAFEARQSLIVRGLFPMLADPRHPAESTSTTNESV---LKVALDHGKASGVIKSHD 276
                   +R S + RG++P L   + P  +     E V   LK  ++H    G+I   D
Sbjct: 439 ---RNPAASRYSHLYRGVWPFLFPEKKPDFNVKVWQEDVDRRLKWGINHALKLGIINKGD 495

Query: 275 RVVVCQ----KVGDSSVVKIIELDD*AKLA 198
            +V  Q     +G ++ V+++  ++   LA
Sbjct: 496 NIVCVQGWRGGMGHTNTVRVVPAEENLGLA 525



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>KPYK_NEUCR (Q7RVA8) Pyruvate kinase (EC 2.7.1.40) (PK)|
          Length = 527

 Score = 62.8 bits (151), Expect = 9e-10
 Identities = 42/155 (27%), Positives = 76/155 (49%), Gaps = 7/155 (4%)
 Frame = -2

Query: 659 YFKRTVKYVGEPMTHLESIASSAVRAAIKVKASVIICFTSSGRAARLIAKYRPTMPVLSV 480
           +F+        P++ +ES A ++VRA++ + A+ I+  ++SG +ARLI+KYRP  P++ +
Sbjct: 377 HFEELCSLAKRPVSIVESCAMASVRASLDLNAAAILVLSTSGESARLISKYRPVCPIIMI 436

Query: 479 VIPRLKTNQLKWSFTGAFEARQSLIVRGLFPMLADPRHPAESTSTTNESV---LKVALDH 309
                              +R + + RG++P L     P  S     E V   +K  L H
Sbjct: 437 T-------------RNDSASRYAHLYRGVYPFLFPESKPDFSKVNWQEDVDRRIKWGLSH 483

Query: 308 GKASGVIKSHDRVVVCQ----KVGDSSVVKIIELD 216
           G    V+   + VVV Q     +G+++  +I++ D
Sbjct: 484 GIGLKVLNEGETVVVVQGWKGGMGNTNTFRIVKAD 518



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>KPYK_XENLA (Q92122) Pyruvate kinase muscle isozyme (EC 2.7.1.40) (Cytosolic|
           thyroid hormone-binding protein) (CTHBP)
          Length = 527

 Score = 62.4 bits (150), Expect = 1e-09
 Identities = 42/117 (35%), Positives = 62/117 (52%), Gaps = 1/117 (0%)
 Frame = -2

Query: 611 ESIASSAVRAAIKVKASVIICFTSSGRAARLIAKYRPTMPVLSVVIPRLKTNQLKWSFTG 432
           E+ A  AV A+ K  +  II  T SGR+A L+++YRP  P++SV                
Sbjct: 406 EATAVGAVEASFKCSSGAIIVLTKSGRSAHLLSRYRPRAPIISVT-------------RN 452

Query: 431 AFEARQSLIVRGLFPML-ADPRHPAESTSTTNESVLKVALDHGKASGVIKSHDRVVV 264
              ARQ+ + RG+FP+L  +  H  E+ +   +S +  A+D GKA G  KS D V+V
Sbjct: 453 GQTARQAHLYRGIFPVLYREAVH--EAWAEDVDSRVNFAMDIGKARGFFKSGDVVIV 507



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>KPYK_YARLI (P30614) Pyruvate kinase (EC 2.7.1.40) (PK)|
          Length = 515

 Score = 60.5 bits (145), Expect = 5e-09
 Identities = 46/142 (32%), Positives = 71/142 (50%), Gaps = 7/142 (4%)
 Frame = -2

Query: 626 PMTHLESIASSAVRAAIKVKASVIICFTSSGRAARLIAKYRPTMPVLSVVIPRLKTNQLK 447
           P   +E+IA SAV A+ + +A  II  ++SG +ARL +KYRP  P+L V           
Sbjct: 386 PTETVETIAISAVSASFEQQARAIIVLSTSGTSARLCSKYRPNCPILMVT---------- 435

Query: 446 WSFTGAFEARQSLIVRGLFPML---ADPRHPAESTSTTNESVLKVALDHGKASGVIKSHD 276
                A  AR S + RG++P +   A   +PAE      E  LK  +D   A G++   D
Sbjct: 436 ---RNAQAARFSHLYRGVYPFIYHKARASNPAEWQHDVEER-LKWGMDEAVALGILNKGD 491

Query: 275 RVVVCQ----KVGDSSVVKIIE 222
            VV  Q     +G ++ ++++E
Sbjct: 492 VVVAIQGWTGGLGHTNTLRVLE 513



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>KPYK_CHICK (P00548) Pyruvate kinase muscle isozyme (EC 2.7.1.40)|
          Length = 529

 Score = 60.1 bits (144), Expect = 6e-09
 Identities = 38/117 (32%), Positives = 66/117 (56%), Gaps = 1/117 (0%)
 Frame = -2

Query: 611 ESIASSAVRAAIKVKASVIICFTSSGRAARLIAKYRPTMPVLSVVIPRLKTNQLKWSFTG 432
           +++A+ AV A+ K  A+ +I  T SGR+A L+++YRP  P+++V     + +Q       
Sbjct: 408 DAMAAGAVEASFKCLAAALIVMTESGRSAHLVSRYRPRAPIIAVT----RNDQ------- 456

Query: 431 AFEARQSLIVRGLFPMLA-DPRHPAESTSTTNESVLKVALDHGKASGVIKSHDRVVV 264
              ARQ+ + RG+FP+L   P H A +     +  + + ++ GKA G  K+ D V+V
Sbjct: 457 --TARQAHLYRGVFPVLCKQPAHDAWAEDV--DLRVNLGMNVGKARGFFKTGDLVIV 509



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>KPYK2_CANGA (Q6FV12) Pyruvate kinase 2 (EC 2.7.1.40) (PK 2)|
          Length = 508

 Score = 60.1 bits (144), Expect = 6e-09
 Identities = 42/139 (30%), Positives = 72/139 (51%), Gaps = 5/139 (3%)
 Frame = -2

Query: 629 EPMTHLESIASSAVRAAIKVKASVIICFTSSGRAARLIAKYRPTMPVLSVV-IPRLKTNQ 453
           +P +  E++A+SAV A  +  A +I+  ++SG  ARL++KYRP  P++ V   PR     
Sbjct: 375 KPTSTTETVAASAVAAVQEQGAKLILVLSTSGNTARLVSKYRPQCPIVLVTRNPR----- 429

Query: 452 LKWSFTGAFEARQSLIVRGLFPMLADPRHPAESTSTTNESVLKVALDHGKASGVIKSHDR 273
                     AR S + RG+FP + + + P +  S    + L+  +D  K  G +K+ D 
Sbjct: 430 ---------TARFSHLFRGVFPFVYE-KEPLDDWSEDTHARLRFGVDMAKEYGFVKNGDA 479

Query: 272 VVVCQ----KVGDSSVVKI 228
           V+  Q     VG S+ +++
Sbjct: 480 VISIQGFKGGVGHSNTMRV 498



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>KPYK1_CANGA (Q6FIS9) Pyruvate kinase 1 (EC 2.7.1.40) (PK 1)|
          Length = 501

 Score = 58.9 bits (141), Expect = 1e-08
 Identities = 41/138 (29%), Positives = 68/138 (49%), Gaps = 4/138 (2%)
 Frame = -2

Query: 629 EPMTHLESIASSAVRAAIKVKASVIICFTSSGRAARLIAKYRPTMPVLSVVIPRLKTNQL 450
           +P +  E++A+SAV A  + KA  II  ++SG  ARL++KYRP  P++ V          
Sbjct: 375 KPTSTTETVAASAVAAVFEQKAKAIIVLSTSGTTARLVSKYRPNCPIILVT--------- 425

Query: 449 KWSFTGAFEARQSLIVRGLFPMLADPRHPAESTSTTNESVLKVALDHGKASGVIKSHDRV 270
                 A  AR S + RG+FP + +    ++ T    E+ L   ++     G++K  D  
Sbjct: 426 ----RNARTARFSHLYRGVFPFVYEKESVSDWTEDV-EARLNFGIEQAIEFGILKKGDTY 480

Query: 269 VVCQ----KVGDSSVVKI 228
           V  Q     VG S+ +++
Sbjct: 481 VSIQGFKAGVGHSNTLQV 498



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>KPYK_TRIRE (P31865) Pyruvate kinase (EC 2.7.1.40) (PK)|
          Length = 538

 Score = 58.9 bits (141), Expect = 1e-08
 Identities = 44/155 (28%), Positives = 75/155 (48%), Gaps = 7/155 (4%)
 Frame = -2

Query: 659 YFKRTVKYVGEPMTHLESIASSAVRAAIKVKASVIICFTSSGRAARLIAKYRPTMPVLSV 480
           +F+     V  P++ +ES A +AVRA++ + A  II  ++SG +ARL++KYRP  P+  V
Sbjct: 387 HFEEMCTLVKRPVSTVESCAMAAVRASLDLGAGGIIVLSTSGDSARLLSKYRPVCPIFMV 446

Query: 479 VIPRLKTNQLKWSFTGAFEARQSLIVRGLFPMLADPRHPAESTSTTNESV---LKVALDH 309
                              +R S + RG++P L   + P   T    E V   +K A+  
Sbjct: 447 T-------------RNPTTSRFSHLYRGVYPFLYPEQKPDFDTVNWQEDVDKRIKWAVTR 493

Query: 308 GKASGVIKSHDRVVVCQ----KVGDSSVVKIIELD 216
                 + + D VVV Q     +G+++ ++I+  D
Sbjct: 494 AIELKTLTAGDTVVVVQGWKGGMGNTNTLRIVRAD 528



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>KPYK1_YEAST (P00549) Pyruvate kinase 1 (EC 2.7.1.40) (PK 1)|
          Length = 500

 Score = 58.5 bits (140), Expect = 2e-08
 Identities = 38/125 (30%), Positives = 62/125 (49%), Gaps = 1/125 (0%)
 Frame = -2

Query: 629 EPMTHLESIASSAVRAAIKVKASVIICFTSSGRAARLIAKYRPTMPVLSVV-IPRLKTNQ 453
           +P +  E++A+SAV A  + KA  II  ++SG   RL++KYRP  P++ V   PR     
Sbjct: 374 KPTSTTETVAASAVAAVFEQKAKAIIVLSTSGTTPRLVSKYRPNCPIILVTRCPR----- 428

Query: 452 LKWSFTGAFEARQSLIVRGLFPMLADPRHPAESTSTTNESVLKVALDHGKASGVIKSHDR 273
                     AR S + RG+FP + + + P    +   E+ +   ++  K  G++K  D 
Sbjct: 429 ---------AARFSHLYRGVFPFVFE-KEPVSDWTDDVEARINFGIEKAKEFGILKKGDT 478

Query: 272 VVVCQ 258
            V  Q
Sbjct: 479 YVSIQ 483



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>KPYM_RAT (P11980) Pyruvate kinase isozymes M1/M2 (EC 2.7.1.40) (Pyruvate|
           kinase muscle isozyme)
          Length = 530

 Score = 57.4 bits (137), Expect = 4e-08
 Identities = 38/133 (28%), Positives = 66/133 (49%)
 Frame = -2

Query: 662 LYFKRTVKYVGEPMTHLESIASSAVRAAIKVKASVIICFTSSGRAARLIAKYRPTMPVLS 483
           L F+   +   +    LE++A  +V A+ K  A+ +I  T SGR+A  +A+YRP  P+++
Sbjct: 392 LLFEELARASSQSTDPLEAMAMGSVEASYKCLAAALIVLTESGRSAHQVARYRPRAPIIA 451

Query: 482 VVIPRLKTNQLKWSFTGAFEARQSLIVRGLFPMLADPRHPAESTSTTNESVLKVALDHGK 303
           V                   ARQ+ + RG+FP+L       ++ +   +  + +A++ GK
Sbjct: 452 VT-------------RNPQTARQAHLYRGIFPVLCKDA-VLDAWAEDVDLRVNLAMNVGK 497

Query: 302 ASGVIKSHDRVVV 264
           A G  K  D V+V
Sbjct: 498 ARGFFKKGDVVIV 510



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>KPYM_PONPY (Q5NVN0) Pyruvate kinase isozyme M1 (EC 2.7.1.40)|
          Length = 530

 Score = 57.4 bits (137), Expect = 4e-08
 Identities = 40/132 (30%), Positives = 66/132 (50%), Gaps = 1/132 (0%)
 Frame = -2

Query: 656 FKRTVKYVGEPMTHLESIASSAVRAAIKVKASVIICFTSSGRAARLIAKYRPTMPVLSVV 477
           F+  V+        +E++A  +V A+ K  A+ +I  T SGR+A  +A+YRP  P+++V 
Sbjct: 394 FEELVRASSHSTDLMEAMAMGSVEASYKCLAAALIVLTESGRSAHQVARYRPRAPIIAVT 453

Query: 476 IPRLKTNQLKWSFTGAFEARQSLIVRGLFPMLA-DPRHPAESTSTTNESVLKVALDHGKA 300
                             ARQ+ + RG+FP+L  DP    E+ +   +  +  A++ GKA
Sbjct: 454 -------------RNPQTARQAHLYRGIFPVLCKDP--VQEAWAEDVDLRVNFAMNVGKA 498

Query: 299 SGVIKSHDRVVV 264
            G  K  D V+V
Sbjct: 499 RGFFKKGDVVIV 510



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>KPYK_SACKL (Q875S4) Pyruvate kinase (EC 2.7.1.40) (PK)|
          Length = 501

 Score = 57.4 bits (137), Expect = 4e-08
 Identities = 41/143 (28%), Positives = 72/143 (50%), Gaps = 5/143 (3%)
 Frame = -2

Query: 638 YVGEPMTHLESIASSAVRAAIKVKASVIICFTSSGRAARLIAKYRPTMPVLSVV-IPRLK 462
           +  +P +  E+IA++AV +  + KA  II  +++G   RL++KY+P +P++ V   PR  
Sbjct: 372 FTPKPTSTTETIAAAAVSSVFEQKAKAIIVLSTTGDTPRLVSKYKPNVPIVMVTRNPR-- 429

Query: 461 TNQLKWSFTGAFEARQSLIVRGLFPMLADPRHPAESTSTTNESVLKVALDHGKASGVIKS 282
                        AR S + RG+FP + +    +E T    ES L   +   K  G++K 
Sbjct: 430 ------------AARFSHLYRGVFPFVYESDTESEWTKDV-ESRLNFGIAKAKEFGMLKE 476

Query: 281 HDRVVVCQ----KVGDSSVVKII 225
            D +V  Q     VG S+ ++++
Sbjct: 477 GDTIVTIQGFAAGVGHSNTLRVL 499



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>KPYM_RABIT (P11974) Pyruvate kinase isozymes M1/M2 (EC 2.7.1.40) (Pyruvate|
           kinase muscle isozyme)
          Length = 530

 Score = 57.0 bits (136), Expect = 5e-08
 Identities = 38/118 (32%), Positives = 66/118 (55%), Gaps = 1/118 (0%)
 Frame = -2

Query: 614 LESIASSAVRAAIKVKASVIICFTSSGRAARLIAKYRPTMPVLSVVIPRLKTNQLKWSFT 435
           +E++A  +V A+ K  A+ +I  T SGR+A  +A+YRP  P+++V     + +Q      
Sbjct: 408 MEAMAMGSVEASYKCLAAALIVLTESGRSAHQVARYRPRAPIIAVT----RNHQ------ 457

Query: 434 GAFEARQSLIVRGLFPMLA-DPRHPAESTSTTNESVLKVALDHGKASGVIKSHDRVVV 264
               ARQ+ + RG+FP++  DP    E+ +   +  + +A++ GKA G  K  D V+V
Sbjct: 458 ---TARQAHLYRGIFPVVCKDP--VQEAWAEDVDLRVNLAMNVGKARGFFKKGDVVIV 510



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>KPYM_FELCA (P11979) Pyruvate kinase isozyme M1 (EC 2.7.1.40) (Pyruvate kinase|
           muscle isozyme)
          Length = 530

 Score = 57.0 bits (136), Expect = 5e-08
 Identities = 40/132 (30%), Positives = 70/132 (53%), Gaps = 1/132 (0%)
 Frame = -2

Query: 656 FKRTVKYVGEPMTHLESIASSAVRAAIKVKASVIICFTSSGRAARLIAKYRPTMPVLSVV 477
           F+  V+        +E++A  +V A+ K  A+ +I  T SGR+A  +A+YRP  P+++V 
Sbjct: 394 FEELVRGSSHSTDLMEAMAMGSVEASYKCLAAALIVLTESGRSAHQVARYRPRAPIIAVT 453

Query: 476 IPRLKTNQLKWSFTGAFEARQSLIVRGLFPMLA-DPRHPAESTSTTNESVLKVALDHGKA 300
               + +Q          ARQ+ + RG+FP++  DP    E+ +   +  + +A++ GKA
Sbjct: 454 ----RNHQ---------TARQAHLYRGIFPVVCKDP--VQEAWAEDVDLRVNLAMNVGKA 498

Query: 299 SGVIKSHDRVVV 264
            G  K  D V+V
Sbjct: 499 RGFFKHGDVVIV 510



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>KPYK_DROME (O62619) Pyruvate kinase (EC 2.7.1.40) (PK)|
          Length = 533

 Score = 57.0 bits (136), Expect = 5e-08
 Identities = 43/134 (32%), Positives = 70/134 (52%), Gaps = 5/134 (3%)
 Frame = -2

Query: 602 ASSAVRAAIKVKASVIICFTSSGRAARLIAKYRPTMPVLSVVIPRLKTNQLKWSFTGAFE 423
           A +AV AA K KAS I+  T+SG++A  ++KYRP  P+++V                A  
Sbjct: 415 AIAAVEAATKAKASAIVVITTSGKSAFQVSKYRPRCPIIAVT-------------RFAQT 461

Query: 422 ARQSLIVRGLFPMLADPRHPAESTSTTNESV-LKVALDHGKASGVIKSHDRVVVC----Q 258
           ARQ+ + RGL P++   + P       +  V ++  L  GK +G IK+ D VVV     Q
Sbjct: 462 ARQAHLYRGLVPLIY--KEPGLGDWLKDVDVRVQFGLQVGKKNGFIKTGDSVVVVTGWKQ 519

Query: 257 KVGDSSVVKIIELD 216
             G ++ ++I+ ++
Sbjct: 520 GSGFTNTIRIVTVE 533



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>KPYK2_TRYBB (P30616) Pyruvate kinase 2 (EC 2.7.1.40) (PK 2)|
          Length = 499

 Score = 55.8 bits (133), Expect = 1e-07
 Identities = 39/121 (32%), Positives = 60/121 (49%)
 Frame = -2

Query: 626 PMTHLESIASSAVRAAIKVKASVIICFTSSGRAARLIAKYRPTMPVLSVVIPRLKTNQLK 447
           PM   E++ SSAV +A +V+A  ++  +++GR+ARLI+KYRP  P++ V   RL+T    
Sbjct: 374 PMCPEEAVCSSAVASAFEVQAKAMLVLSNTGRSARLISKYRPNCPIICVT-TRLQT---- 428

Query: 446 WSFTGAFEARQSLIVRGLFPMLADPRHPAESTSTTNESVLKVALDHGKASGVIKSHDRVV 267
                    RQ  + R +  +  D     E      E  +K+ LD  K      + D VV
Sbjct: 429 --------CRQLNVTRSVVSVFYDAAKSGEDKD--KEKRVKLGLDFAKKEKYASTGDVVV 478

Query: 266 V 264
           V
Sbjct: 479 V 479



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>KPYK1_TRYBB (P30615) Pyruvate kinase 1 (EC 2.7.1.40) (PK 1)|
          Length = 499

 Score = 55.8 bits (133), Expect = 1e-07
 Identities = 39/121 (32%), Positives = 60/121 (49%)
 Frame = -2

Query: 626 PMTHLESIASSAVRAAIKVKASVIICFTSSGRAARLIAKYRPTMPVLSVVIPRLKTNQLK 447
           PM   E++ SSAV +A +V+A  ++  +++GR+ARLI+KYRP  P++ V   RL+T    
Sbjct: 374 PMCPEEAVCSSAVASAFEVQAKAMLVLSNTGRSARLISKYRPNCPIICVT-TRLQT---- 428

Query: 446 WSFTGAFEARQSLIVRGLFPMLADPRHPAESTSTTNESVLKVALDHGKASGVIKSHDRVV 267
                    RQ  + R +  +  D     E      E  +K+ LD  K      + D VV
Sbjct: 429 --------CRQLNVTRSVVSVFYDAAKSGEDKD--KEKRVKLGLDFAKKEKYASTGDVVV 478

Query: 266 V 264
           V
Sbjct: 479 V 479



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>KPYM_MOUSE (P52480) Pyruvate kinase isozyme M2 (EC 2.7.1.40)|
          Length = 530

 Score = 55.1 bits (131), Expect = 2e-07
 Identities = 40/118 (33%), Positives = 58/118 (49%), Gaps = 2/118 (1%)
 Frame = -2

Query: 611 ESIASSAVRAAIKVKASVIICFTSSGRAARLIAKYRPTMPVLSVVIPRLKTNQLKWSFTG 432
           E+ A  AV A+ K  +  II  T SGR+A  +A+YRP  P+++V                
Sbjct: 409 EAAAVGAVEASFKCCSGAIIVLTKSGRSAHQVARYRPRAPIIAVT-------------RN 455

Query: 431 AFEARQSLIVRGLFPMLADPRHPAESTSTTNESVLKV--ALDHGKASGVIKSHDRVVV 264
              ARQ+ + RG+FP+L      A   +   +  L+V  A+D GKA G  K  D V+V
Sbjct: 456 PQTARQAHLYRGIFPVLC---KDAVLNAWAEDVDLRVNLAMDVGKARGFFKKGDVVIV 510



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>KPYM_HUMAN (P14618) Pyruvate kinase isozymes M1/M2 (EC 2.7.1.40) (Pyruvate|
           kinase muscle isozyme) (Cytosolic thyroid
           hormone-binding protein) (CTHBP) (THBP1)
          Length = 530

 Score = 55.1 bits (131), Expect = 2e-07
 Identities = 39/117 (33%), Positives = 59/117 (50%), Gaps = 1/117 (0%)
 Frame = -2

Query: 611 ESIASSAVRAAIKVKASVIICFTSSGRAARLIAKYRPTMPVLSVVIPRLKTNQLKWSFTG 432
           E+ A  AV A+ K  +  II  T SGR+A  +A+YRP  P+++V                
Sbjct: 409 EATAVGAVEASFKCCSGAIIVLTKSGRSAHQVARYRPRAPIIAVT-------------RN 455

Query: 431 AFEARQSLIVRGLFPMLA-DPRHPAESTSTTNESVLKVALDHGKASGVIKSHDRVVV 264
              ARQ+ + RG+FP+L  DP    E+ +   +  +  A++ GKA G  K  D V+V
Sbjct: 456 PQTARQAHLYRGIFPVLCKDP--VQEAWAEDVDLRVNFAMNVGKARGFFKKGDVVIV 510



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>KPYK_EIMTE (O44006) Pyruvate kinase (EC 2.7.1.40) (PK)|
          Length = 531

 Score = 55.1 bits (131), Expect = 2e-07
 Identities = 39/152 (25%), Positives = 71/152 (46%), Gaps = 5/152 (3%)
 Frame = -2

Query: 656 FKRTVKYVGEPMTHLESIASSAVRAAIKVKASVIICFTSSGRAARLIAKYRPTMPVLSVV 477
           F+ T +    P+   E++A +AV  A  + AS+I+  T +GR ARLIAKYRP  P+L++ 
Sbjct: 400 FRATCQATMTPIDTQEAVARAAVETAQSINASLILALTETGRTARLIAKYRPMQPILALS 459

Query: 476 IPRLKTNQLKWSFTGAFEARQSLIVRGLFPMLADPRHPAESTSTTNESVLKVALDHGKAS 297
                  QL+             ++RG+   L         T    + +++ AL   K  
Sbjct: 460 ASEETIKQLQ-------------VIRGVTTFLV-------PTFQGTDQLIRNALSAAKEL 499

Query: 296 GVIKSHDRVVVCQKV-----GDSSVVKIIELD 216
            ++   D +V    +     G S+++K++ ++
Sbjct: 500 QLVSEGDSIVAVHGIKEEVAGWSNLLKVLVVE 531



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>KPYK_KLULA (Q875M9) Pyruvate kinase (EC 2.7.1.40) (PK)|
          Length = 501

 Score = 55.1 bits (131), Expect = 2e-07
 Identities = 39/140 (27%), Positives = 70/140 (50%), Gaps = 5/140 (3%)
 Frame = -2

Query: 629 EPMTHLESIASSAVRAAIKVKASVIICFTSSGRAARLIAKYRPTMPVLSVV-IPRLKTNQ 453
           +P +  E+IA+++V A  + KA  +I  +++G   RL+AKY+P +P++ V   PR     
Sbjct: 375 KPTSTTETIAAASVSAVFEQKARALIVLSTTGDTPRLVAKYKPNVPIVMVTRNPR----- 429

Query: 452 LKWSFTGAFEARQSLIVRGLFPMLADPRHPAESTSTTNESVLKVALDHGKASGVIKSHDR 273
                     AR S + RG+FP + D    +E T    E  +   +   K  G++   D 
Sbjct: 430 ---------AARFSHLYRGVFPFVYDESSDSEWTVDV-EKRINFGVKKAKEFGILVDGDT 479

Query: 272 VVVCQ----KVGDSSVVKII 225
           +V  Q     VG+S+ ++++
Sbjct: 480 IVTIQGFAAGVGNSNTLRVL 499



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>KPYK_SACCA (Q875Z9) Pyruvate kinase (EC 2.7.1.40) (PK)|
          Length = 501

 Score = 54.7 bits (130), Expect = 3e-07
 Identities = 41/125 (32%), Positives = 61/125 (48%), Gaps = 1/125 (0%)
 Frame = -2

Query: 629 EPMTHLESIASSAVRAAIKVKASVIICFTSSGRAARLIAKYRPTMPVLSVV-IPRLKTNQ 453
           +P +  E++A+SAV A  + KA  II  ++SG   RL++KYRP  P++ V   PR     
Sbjct: 375 KPTSTTETVAASAVAAVYEQKAKAIIVLSTSGTTPRLVSKYRPDCPIILVTRNPR----- 429

Query: 452 LKWSFTGAFEARQSLIVRGLFPMLADPRHPAESTSTTNESVLKVALDHGKASGVIKSHDR 273
                     AR S + RG+FP + +    A+ T    E  LK  ++     GV+K  D 
Sbjct: 430 ---------AARFSHLSRGVFPFVYEADSVADWTEDV-ELRLKFGIEKAIEMGVMKKGDT 479

Query: 272 VVVCQ 258
            V  Q
Sbjct: 480 YVSIQ 484



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>KPYK_ASHGO (Q759A9) Pyruvate kinase (EC 2.7.1.40) (PK)|
          Length = 501

 Score = 54.7 bits (130), Expect = 3e-07
 Identities = 38/140 (27%), Positives = 70/140 (50%), Gaps = 5/140 (3%)
 Frame = -2

Query: 629 EPMTHLESIASSAVRAAIKVKASVIICFTSSGRAARLIAKYRPTMPVLSVV-IPRLKTNQ 453
           +P    E+IA++AV A  + KA  I+  ++SG   RL++KY+P +P++ V   PR     
Sbjct: 375 KPTPTSETIAAAAVAATFEQKAKAIVVLSTSGDTTRLVSKYKPNVPIVMVTRNPR----- 429

Query: 452 LKWSFTGAFEARQSLIVRGLFPMLADPRHPAESTSTTNESVLKVALDHGKASGVIKSHDR 273
                     AR   + RG+FP + + +  A+  +   E+ L   ++  K  G++   D 
Sbjct: 430 ---------AARYCHLHRGVFPFVYE-QEAADEWTDDVEARLNFGVEKSKELGILSEGDT 479

Query: 272 VVVCQ----KVGDSSVVKII 225
           +V  Q     VG S+ ++++
Sbjct: 480 IVTIQGFASGVGHSNTLRVL 499



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>KPYK_BACSU (P80885) Pyruvate kinase (EC 2.7.1.40) (PK) (Vegetative protein 17)|
           (VEG17)
          Length = 585

 Score = 53.9 bits (128), Expect = 4e-07
 Identities = 38/136 (27%), Positives = 68/136 (50%), Gaps = 1/136 (0%)
 Frame = -2

Query: 623 MTHLESIASSAVRAAIKVKASVIICFTSSGRAARLIAKYRPTMPVLSVVIPRLKTNQLKW 444
           MT  ++I  S    AI + A+ I+  T SG  AR+IAKYRP  P+++V +          
Sbjct: 354 MTITDAIGQSVAHTAINLNAAAIVTPTESGHTARMIAKYRPQAPIVAVTV---------- 403

Query: 443 SFTGAFEARQSLIVRGLFPMLADPRHPAESTSTTNESVLKVALDHGKASGVIKSHDRVVV 264
                  +R+  +V G+F          ++ S+T+E +L+ A+     SG++K  D +V+
Sbjct: 404 ---NDSISRKLALVSGVF------AESGQNASSTDE-MLEDAVQKSLNSGIVKHGDLIVI 453

Query: 263 -CQKVGDSSVVKIIEL 219
               VG+S    ++++
Sbjct: 454 TAGTVGESGTTNLMKV 469



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>KPYK2_YEAST (P52489) Pyruvate kinase 2 (EC 2.7.1.40) (PK 2)|
          Length = 506

 Score = 53.5 bits (127), Expect = 6e-07
 Identities = 36/138 (26%), Positives = 70/138 (50%), Gaps = 4/138 (2%)
 Frame = -2

Query: 629 EPMTHLESIASSAVRAAIKVKASVIICFTSSGRAARLIAKYRPTMPVLSVVIPRLKTNQL 450
           +P +  E++A++A  A ++     I+  +++G  ARL++KYRP+ P++ V          
Sbjct: 376 KPTSTTETVAAAATAAILEQDGKAIVVLSTTGNTARLLSKYRPSCPIILVT--------- 426

Query: 449 KWSFTGAFEARQSLIVRGLFPMLADPRHPAESTSTTNESVLKVALDHGKASGVIKSHDRV 270
                 A  AR + + RG+FP L +P+   +     +   LK  ++  ++ G++ + D V
Sbjct: 427 ----RHARTARIAHLYRGVFPFLYEPKRLDDWGEDVHRR-LKFGVEMARSFGMVDNGDTV 481

Query: 269 VVCQ----KVGDSSVVKI 228
           V  Q     VG S+ ++I
Sbjct: 482 VSIQGFKGGVGHSNTLRI 499



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>KPYR_HUMAN (P30613) Pyruvate kinase isozymes R/L (EC 2.7.1.40) (R-type/L-type|
           pyruvate kinase) (Red cell/liver pyruvate kinase)
          Length = 574

 Score = 53.1 bits (126), Expect = 7e-07
 Identities = 38/117 (32%), Positives = 61/117 (52%), Gaps = 1/117 (0%)
 Frame = -2

Query: 611 ESIASSAVRAAIKVKASVIICFTSSGRAARLIAKYRPTMPVLSVVIPRLKTNQLKWSFTG 432
           E  A  AV AA K  A+ II  T++GR+A+L+++YRP   V++V                
Sbjct: 453 EVTAIGAVEAAFKCCAAAIIVLTTTGRSAQLLSRYRPRAAVIAVT-------------RS 499

Query: 431 AFEARQSLIVRGLFPMLADPRHPAESTSTTN-ESVLKVALDHGKASGVIKSHDRVVV 264
           A  ARQ  + RG+FP+L   R P E+    + +  ++  ++ GK  G ++  D V+V
Sbjct: 500 AQAARQVHLCRGVFPLLY--REPPEAIWADDVDRRVQFGIESGKLRGFLRVGDLVIV 554



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>KPYR_MOUSE (P53657) Pyruvate kinase isozymes R/L (EC 2.7.1.40) (L-PK)|
          Length = 574

 Score = 51.6 bits (122), Expect = 2e-06
 Identities = 37/117 (31%), Positives = 60/117 (51%), Gaps = 1/117 (0%)
 Frame = -2

Query: 611 ESIASSAVRAAIKVKASVIICFTSSGRAARLIAKYRPTMPVLSVVIPRLKTNQLKWSFTG 432
           E  A  AV A+ K  A+ II  T +GR+A+L+++YRP   V++V                
Sbjct: 453 EVTAIGAVEASFKCCAAAIIVLTKTGRSAQLLSRYRPRAAVIAVT-------------RS 499

Query: 431 AFEARQSLIVRGLFPMLADPRHPAESTSTTN-ESVLKVALDHGKASGVIKSHDRVVV 264
           A  ARQ  + RG+FP+L   R P E+    + +  ++  ++ GK  G ++  D V+V
Sbjct: 500 AQAARQVHLSRGVFPLLY--REPPEAVWADDVDRRVQFGIESGKLRGFLRVGDLVIV 554



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>KPYR_CANFA (Q29536) Pyruvate kinase isozyme R (EC 2.7.1.40) (Fragment)|
          Length = 519

 Score = 51.2 bits (121), Expect = 3e-06
 Identities = 36/117 (30%), Positives = 61/117 (52%), Gaps = 1/117 (0%)
 Frame = -2

Query: 611 ESIASSAVRAAIKVKASVIICFTSSGRAARLIAKYRPTMPVLSVVIPRLKTNQLKWSFTG 432
           E  A + V AA K  A+ II  T +GR+A+L+++YRP   V++V                
Sbjct: 398 EVTAIATVEAAFKCCAAAIIVLTKTGRSAQLLSRYRPRAAVIAVT-------------RS 444

Query: 431 AFEARQSLIVRGLFPML-ADPRHPAESTSTTNESVLKVALDHGKASGVIKSHDRVVV 264
           A  ARQ+ + RG+FP+L ++P  P    +   +  ++  ++ GK  G ++  D V+V
Sbjct: 445 AQAARQAHLCRGVFPLLYSEP--PEAIWADDVDRRVQFGIESGKLRGFLRVGDLVIV 499



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>KPYR_RAT (P12928) Pyruvate kinase isozymes R/L (EC 2.7.1.40) (L-PK)|
          Length = 574

 Score = 50.8 bits (120), Expect = 4e-06
 Identities = 37/117 (31%), Positives = 60/117 (51%), Gaps = 1/117 (0%)
 Frame = -2

Query: 611 ESIASSAVRAAIKVKASVIICFTSSGRAARLIAKYRPTMPVLSVVIPRLKTNQLKWSFTG 432
           E  A  AV A+ K  A+ II  T +GR+A+L+++YRP   V++V                
Sbjct: 453 EVTAIGAVEASFKCCAAAIIVLTKTGRSAQLLSQYRPRAAVIAVT-------------RS 499

Query: 431 AFEARQSLIVRGLFPMLADPRHPAESTSTTN-ESVLKVALDHGKASGVIKSHDRVVV 264
           A  ARQ  + RG+FP+L   R P E+    + +  ++  ++ GK  G ++  D V+V
Sbjct: 500 AQAARQVHLSRGVFPLLY--REPPEAIWADDVDRRVQFGIESGKLRGFLRVGDLVIV 554



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>KPYK_TRYBO (Q27788) Pyruvate kinase (EC 2.7.1.40) (PK)|
          Length = 498

 Score = 50.4 bits (119), Expect = 5e-06
 Identities = 36/120 (30%), Positives = 57/120 (47%)
 Frame = -2

Query: 626 PMTHLESIASSAVRAAIKVKASVIICFTSSGRAARLIAKYRPTMPVLSVVIPRLKTNQLK 447
           P+   E+I SSAV +  ++ A  I+  T++GR+A +++KYRP +P++        + +L 
Sbjct: 373 PLIPEEAICSSAVNSIFELHAKAILVLTNTGRSAHMVSKYRPPVPIICA------SQELD 426

Query: 446 WSFTGAFEARQSLIVRGLFPMLADPRHPAESTSTTNESVLKVALDHGKASGVIKSHDRVV 267
                    R   I RG  P+  D            E  + +A+D GK  GV K  D VV
Sbjct: 427 -------VCRLLSITRGTIPVYYDTEKLGPDYD--REKRVGLAIDVGKQMGVFKEGDVVV 477



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>KPYK_SCHPO (Q10208) Pyruvate kinase (EC 2.7.1.40) (PK)|
          Length = 509

 Score = 50.1 bits (118), Expect = 6e-06
 Identities = 35/133 (26%), Positives = 64/133 (48%), Gaps = 2/133 (1%)
 Frame = -2

Query: 611 ESIASSAVRAAIKVKASVIICFTSSGRAARLIAKYRPTMPVLSVV-IPRLKTNQLKWSFT 435
           E+ A +A+ A+I+  A  I+  ++SG  ARL +KYRP++P++ V   P+           
Sbjct: 388 ETTAVAAIGASIESDAKAIVVLSTSGNTARLCSKYRPSIPIVMVTRCPQ----------- 436

Query: 434 GAFEARQSLIVRGLFPMLADPRHPAESTSTTNESVLKVALDHGKASGVIKSHDRVVVCQ- 258
               ARQS + RG++P++ + + P        ++ +           ++K  D+++V Q 
Sbjct: 437 ---RARQSHLNRGVYPVIYE-KEPLSDWQKDVDARVAYGCQQAYKMNILKKGDKIIVLQG 492

Query: 257 KVGDSSVVKIIEL 219
            VG      I  L
Sbjct: 493 AVGGKGHTSIFRL 505



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>KPYK_LEIME (Q27686) Pyruvate kinase (EC 2.7.1.40) (PK)|
          Length = 499

 Score = 49.7 bits (117), Expect = 8e-06
 Identities = 36/136 (26%), Positives = 63/136 (46%)
 Frame = -2

Query: 671 NQDLYFKRTVKYVGEPMTHLESIASSAVRAAIKVKASVIICFTSSGRAARLIAKYRPTMP 492
           N+ ++F    K    PM+  E++  SAV +  + KA  ++  +++G  ARL+AKYRP  P
Sbjct: 359 NEYVFFNSIKKLQHIPMSADEAVCGSAVNSVSETKAKAMVVLSNTGAGARLVAKYRPNCP 418

Query: 491 VLSVVIPRLKTNQLKWSFTGAFEARQSLIVRGLFPMLADPRHPAESTSTTNESVLKVALD 312
           ++ V   RL+T             RQ  I +G+  +  D            E  +   ++
Sbjct: 419 IVCVT-TRLQT------------CRQLNITQGVESVFFDADKLGHDEG--KEHRVAAGVE 463

Query: 311 HGKASGVIKSHDRVVV 264
             K+ G +++ D  VV
Sbjct: 464 FAKSKGYVQTGDYCVV 479



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>KPYK_LACDE (P34038) Pyruvate kinase (EC 2.7.1.40) (PK)|
          Length = 589

 Score = 49.3 bits (116), Expect = 1e-05
 Identities = 45/150 (30%), Positives = 71/150 (47%), Gaps = 2/150 (1%)
 Frame = -2

Query: 662 LYFKRTVKYVGEPMTHLESIASSAVRAAIKVKASVIICFTSSGRAARLIAKYRPTMPVLS 483
           L  +R  +Y G  +T  E+I  S VR A ++    II  TSSG  AR+I+KYRP   +++
Sbjct: 346 LALQRFEEYKGSNVT--EAIGESVVRTAQELGVKTIIAATSSGYTARMISKYRPDATIVA 403

Query: 482 VVIPRLKTNQLKWSFTGAFEARQSLIVRGLFPMLADPRHPAESTSTTNESVLKVALDHGK 303
           +       + L              IV G+ P+LA  + P+ +T    E   +VA +H  
Sbjct: 404 LTFDEKIQHSLG-------------IVWGVEPVLA--KKPS-NTDEMFEEAARVAKEH-- 445

Query: 302 ASGVIKSHDRVVVCQKV--GDSSVVKIIEL 219
             G +K  D V++   V  G S    +++L
Sbjct: 446 --GFVKDGDLVIIVAGVPFGQSGTTNLMKL 473



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>KPYK_BACST (Q02499) Pyruvate kinase (EC 2.7.1.40) (PK)|
          Length = 587

 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 43/168 (25%), Positives = 81/168 (48%), Gaps = 5/168 (2%)
 Frame = -2

Query: 671 NQDLYFKRTVKYVGEPMTHLESIASSAVRAAIKVKASVIICFTSSGRAARLIAKYRPTMP 492
           ++D+  +RT +      T  ++I  S    A+ +  + I+  T SG+  +++AKYRP  P
Sbjct: 342 HRDILSQRTKE---SQTTITDAIGQSVAHTALNLDVAAIVTPTVSGKTPQMVAKYRPKAP 398

Query: 491 VLSVVIPRLKTNQLKWSFTGAFEARQSLIVRGLFPMLADPRHPAESTSTTNESVLKVALD 312
           +++V              +    +R+  +V G++         A   +TT+E +L VA+D
Sbjct: 399 IIAVT-------------SNEAVSRRLALVWGVY------TKEAPHVNTTDE-MLDVAVD 438

Query: 311 HGKASGVIKSHDRVVVCQKV-----GDSSVVKIIELDD*AKLAFAQGL 183
               SG++K  D VV+   V     G ++++K+  + D   LA  QG+
Sbjct: 439 AAVRSGLVKHGDLVVITAGVPVGETGSTNLMKVHVISD--LLAKGQGI 484



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>KPYK_DEBHA (Q6BS75) Pyruvate kinase (EC 2.7.1.40) (PK)|
          Length = 504

 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 35/139 (25%), Positives = 66/139 (47%), Gaps = 4/139 (2%)
 Frame = -2

Query: 626 PMTHLESIASSAVRAAIKVKASVIICFTSSGRAARLIAKYRPTMPVLSVVIPRLKTNQLK 447
           P    E+ A ++V AA +  A  I+  ++SG  +RL++KY+P +PV+ V           
Sbjct: 379 PTPTTETCAMASVSAAYEQDAKAIVVLSTSGFTSRLVSKYKPNVPVMMVT---------- 428

Query: 446 WSFTGAFEARQSLIVRGLFPMLADPRHPAESTSTTNESVLKVALDHGKASGVIKSHDRVV 267
                   AR   + RG++P + + +   ++     E+ L+ A+      G+IK  D +V
Sbjct: 429 ---RNHRAARYCHLYRGVYPFVYE-KKTVDNWQEDVENRLRWAVSEAIDLGIIKKGDSIV 484

Query: 266 VCQ----KVGDSSVVKIIE 222
             Q      G S+ V++++
Sbjct: 485 TIQGWTRGSGHSNTVRVVQ 503



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>KPYK_CHLMU (Q9PK61) Pyruvate kinase (EC 2.7.1.40) (PK)|
          Length = 481

 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 32/119 (26%), Positives = 61/119 (51%), Gaps = 1/119 (0%)
 Frame = -2

Query: 617 HLESIASSAVRAAIKVKASVIICFTSSGRAARLIAKYRPTMPVLSVVIPRLKTNQLKWSF 438
           +LE+I +S ++ A K  A  II +T +G +   ++KYRP +P+++V   R    +L    
Sbjct: 358 YLEAIGASGIQIAEKASAKAIIVYTQTGGSPMFLSKYRPYLPIIAVTPNRNVYYRL---- 413

Query: 437 TGAFEARQSLIVRGLFPMLADPRHPAESTSTTNESVLK-VALDHGKASGVIKSHDRVVV 264
                     +  G++PML         TS +N +V +  A  +G   G++ ++D+++V
Sbjct: 414 ---------AVEWGVYPML---------TSESNRTVWRHQACVYGVEKGILSNYDKILV 454



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>KPYK_CHLTR (P94685) Pyruvate kinase (EC 2.7.1.40) (PK)|
          Length = 485

 Score = 44.7 bits (104), Expect = 3e-04
 Identities = 31/119 (26%), Positives = 59/119 (49%), Gaps = 1/119 (0%)
 Frame = -2

Query: 617 HLESIASSAVRAAIKVKASVIICFTSSGRAARLIAKYRPTMPVLSVVIPRLKTNQLKWSF 438
           +LE+I  S ++ A K  A  II +T +G +   ++KYRP +P+++V   R    +L    
Sbjct: 358 YLEAIGFSGIQIAEKASAKAIIVYTQTGGSPMFLSKYRPYLPIIAVTPNRNVYYRL---- 413

Query: 437 TGAFEARQSLIVRGLFPMLADPRHPAESTSTTNESVLK-VALDHGKASGVIKSHDRVVV 264
                     +  G++PML         T  +N +V +  A  +G   G++ ++D+++V
Sbjct: 414 ---------AVEWGVYPML---------TLESNRTVWRHQACVYGVEKGILSNYDKILV 454



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>KPYK_AGABI (O94122) Pyruvate kinase (EC 2.7.1.40) (PK)|
          Length = 532

 Score = 44.7 bits (104), Expect = 3e-04
 Identities = 34/125 (27%), Positives = 61/125 (48%), Gaps = 2/125 (1%)
 Frame = -2

Query: 626 PMTHLESIASSAVRAAIKVKASVIICFTSSGRAARLIAKYRPTMPVLSVVIPRLKTNQLK 447
           P    E++A +AV AA +  A  ++  ++SG  ARL++KYRP +P+++V     +  Q  
Sbjct: 389 PTETAETVAIAAVAAAAEQDAKALLVLSTSGETARLVSKYRPKIPIITVT----RNEQ-- 442

Query: 446 WSFTGAFEARQSLIVRGLFPM-LADPRHPAESTSTTN-ESVLKVALDHGKASGVIKSHDR 273
                   ARQ  + RG +P    +PR        T+ ++ ++  L +  A  VI+    
Sbjct: 443 -------TARQIHLHRGCYPFWYPEPRGVQNHQWQTDVDNRIRFGLRNALALNVIQPGAS 495

Query: 272 VVVCQ 258
           ++  Q
Sbjct: 496 IIAVQ 500



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>KPYK_BACPY (P51182) Pyruvate kinase (EC 2.7.1.40) (PK)|
          Length = 586

 Score = 43.9 bits (102), Expect = 5e-04
 Identities = 36/145 (24%), Positives = 65/145 (44%), Gaps = 2/145 (1%)
 Frame = -2

Query: 611 ESIASSAVRAAIKVKASVIICFTSSGRAARLIAKYRPTMPVLSVVIPRLKTNQLKWSFTG 432
           E+I  +A   AI +K   ++  T SG  A++IAKYRP  PV++V    + + +L      
Sbjct: 358 EAIGQAAAYTAINLKVKAVLAPTESGHTAKMIAKYRPGCPVIAVTSSEMCSRKLS----- 412

Query: 431 AFEARQSLIVRGLFPMLADPRHPAES--TSTTNESVLKVALDHGKASGVIKSHDRVVVCQ 258
                   ++ G++P++       +     +  ESV    + HG    +       V   
Sbjct: 413 --------LIWGVYPIVGKKASSIDEILQESVEESVKHQYVGHGDVVIITAG----VPVG 460

Query: 257 KVGDSSVVKIIELDD*AKLAFAQGL 183
           + G ++++KI  + D   LA  QG+
Sbjct: 461 EAGTTNLMKIHVIGD--LLARGQGI 483



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>KPYK_LACLA (Q07637) Pyruvate kinase (EC 2.7.1.40) (PK)|
          Length = 502

 Score = 43.9 bits (102), Expect = 5e-04
 Identities = 36/119 (30%), Positives = 57/119 (47%)
 Frame = -2

Query: 620 THLESIASSAVRAAIKVKASVIICFTSSGRAARLIAKYRPTMPVLSVVIPRLKTNQLKWS 441
           T  E +A+S   AA  +   +I+  T SG  ARLI+K+RP   +L++            +
Sbjct: 384 TVTEVVAASVKNAAEAMDIKLIVALTESGNTARLISKHRPNADILAI------------T 431

Query: 440 FTGAFEARQSLIVRGLFPMLADPRHPAESTSTTNESVLKVALDHGKASGVIKSHDRVVV 264
           F    E R  +I  G+ P + +      ST    E   KVAL    ASG+++S D +++
Sbjct: 432 FDEKVE-RGLMINWGVIPTMTE---KPSSTDDMFEVAEKVAL----ASGLVESGDNIII 482



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>KPYK_CLOAB (O08309) Pyruvate kinase (EC 2.7.1.40) (PK)|
          Length = 473

 Score = 42.4 bits (98), Expect = 0.001
 Identities = 36/131 (27%), Positives = 64/131 (48%), Gaps = 5/131 (3%)
 Frame = -2

Query: 605 IASSAVRAAIKVKASVIICFTSSGRAARLIAKYRPTMPVLSVVIPRLKTNQLKWSFTGAF 426
           I+     AA  ++AS II  T +G  AR ++KYRP  PV++V  P  K            
Sbjct: 359 ISLGTCTAAADLEASAIITATQTGSTARTVSKYRPKAPVIAVT-PSEKV----------- 406

Query: 425 EARQSLIVRGLFPMLADPRHPAESTSTTNESVLKVALDHGKASGVIKSHDRVVVCQKV-- 252
            AR+  +  G+ P+++D         +T+E ++  ++D    +G ++  D VVV   V  
Sbjct: 407 -ARKLAMSWGVHPIISD------KFGSTDE-LISTSVDKALEAGYVQKGDLVVVAAGVPT 458

Query: 251 ---GDSSVVKI 228
              G ++++K+
Sbjct: 459 NVSGTTNMLKV 469



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>KPYK_CHLPN (Q9Z984) Pyruvate kinase (EC 2.7.1.40) (PK)|
          Length = 484

 Score = 40.0 bits (92), Expect = 0.007
 Identities = 31/127 (24%), Positives = 60/127 (47%), Gaps = 6/127 (4%)
 Frame = -2

Query: 617 HLESIASSAVRAAIKVKASVIICFTSSGRAARLIAKYRPTMPVLSV-----VIPRLKTNQ 453
           +L +I  + ++ A +  A  +I +T SG +   ++KYRP  P+++V     V  RL    
Sbjct: 358 YLSAIGLAGIQIAERADAKALIVYTESGSSPMFLSKYRPKFPIIAVTPSTSVYYRL---A 414

Query: 452 LKWSFTGAFEARQSLIVRGLFPMLADPRHPAESTSTTNESVLK-VALDHGKASGVIKSHD 276
           L+W               G++PML         T  ++ +V +  A  +G   G++ ++D
Sbjct: 415 LEW---------------GVYPML---------TQESDRAVWRHQACIYGIEQGILSNYD 450

Query: 275 RVVVCQK 255
           R++V  +
Sbjct: 451 RILVLSR 457



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>KPYK2_AGRVI (Q44473) Pyruvate kinase (EC 2.7.1.40) (PK)|
          Length = 482

 Score = 37.7 bits (86), Expect = 0.032
 Identities = 14/43 (32%), Positives = 30/43 (69%)
 Frame = -2

Query: 608 SIASSAVRAAIKVKASVIICFTSSGRAARLIAKYRPTMPVLSV 480
           ++A++A   A+ + + V++ +TSSG  A  I++ RP +P+L++
Sbjct: 359 AVATAAANVAVALGSPVVVAYTSSGTTAARISRARPALPILAL 401



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>KPYK_CLOPE (Q46289) Pyruvate kinase (EC 2.7.1.40) (PK)|
          Length = 474

 Score = 37.4 bits (85), Expect = 0.042
 Identities = 14/49 (28%), Positives = 30/49 (61%)
 Frame = -2

Query: 626 PMTHLESIASSAVRAAIKVKASVIICFTSSGRAARLIAKYRPTMPVLSV 480
           P    ++I+ SA + A K     I+  T +G  A++++KY+P+ P++++
Sbjct: 354 PDAFADAISYSASKTASKFPTKAIVAATQTGSTAKILSKYKPSCPIIAI 402



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>KPYK2_SYNY3 (P73534) Pyruvate kinase 2 (EC 2.7.1.40) (PK 2)|
          Length = 591

 Score = 37.0 bits (84), Expect = 0.055
 Identities = 28/100 (28%), Positives = 51/100 (51%)
 Frame = -2

Query: 608 SIASSAVRAAIKVKASVIICFTSSGRAARLIAKYRPTMPVLSVVIPRLKTNQLKWSFTGA 429
           +I+S+  + A  + A+ I+  T +G  AR ++K+RP  P+L+V  P +            
Sbjct: 362 AISSAVSQIAETLNAAAIMSLTKTGSTARHVSKFRPKTPILAVT-PHVDV---------- 410

Query: 428 FEARQSLIVRGLFPMLADPRHPAESTSTTNESVLKVALDH 309
             +RQ  +V G+ P+L        STS T ++ + VA ++
Sbjct: 411 --SRQLQLVWGVKPLLV---LDLPSTSQTFQAAINVAQEN 445



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>LAMA1_HUMAN (P25391) Laminin alpha-1 chain precursor (Laminin A chain)|
          Length = 3075

 Score = 33.1 bits (74), Expect = 0.80
 Identities = 20/67 (29%), Positives = 25/67 (37%)
 Frame = +3

Query: 393 EASNYE*LSCFKCACEAPLQLICF*TRNDNRQDRHGGPVLGN*PCSSSR*GEANDDRSLN 572
           + S YE   C  C C+    L     ++D   D H G   G  PC     GE  D   L 
Sbjct: 385 KVSPYEDEPCRPCNCDPVGSLSSVCIKDDLHSDLHNGKQPGQCPCKEGYTGEKCDRCQLG 444

Query: 573 FDSRPHC 593
           +   P C
Sbjct: 445 YKDYPTC 451



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>FTHS_LACJO (Q74JC1) Formate--tetrahydrofolate ligase (EC 6.3.4.3)|
           (Formyltetrahydrofolate synthetase) (FHS) (FTHFS)
          Length = 557

 Score = 30.8 bits (68), Expect = 4.0
 Identities = 14/39 (35%), Positives = 24/39 (61%)
 Frame = +1

Query: 541 EVKQMMTEALTLIAARTAEEAIDSKWVMGSPTYFTVRLK 657
           E+K+M  + L +I A+T     D K ++G+P  FT+ +K
Sbjct: 474 EIKKMGKDNLPVIMAKTQYSFTDKKSILGAPKDFTLHVK 512



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>ORYB_ORYSA (P25777) Oryzain beta chain precursor (EC 3.4.22.-)|
          Length = 471

 Score = 30.8 bits (68), Expect = 4.0
 Identities = 26/78 (33%), Positives = 34/78 (43%), Gaps = 13/78 (16%)
 Frame = -1

Query: 600 FLCSAGGYQS*GFGHHLLHLIWTSCK---ANCQVQAHHAC-----PVC-----CHSSSKN 460
           F C AG      FG   L L+W  C    A C  + H +C     PVC       S+SKN
Sbjct: 389 FSCPAGSTCCCAFGFRNLCLVWGCCPVEGATC-CKDHASCCPPDYPVCNTRAGTCSASKN 447

Query: 459 KSIEVELHRRI*SKTITH 406
             + V+  +R  +K  TH
Sbjct: 448 SPLSVKALKRTLAKLNTH 465



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>KPYK2_ECOLI (P21599) Pyruvate kinase II (EC 2.7.1.40) (PK-2)|
          Length = 479

 Score = 29.6 bits (65), Expect = 8.8
 Identities = 31/138 (22%), Positives = 63/138 (45%), Gaps = 6/138 (4%)
 Frame = -2

Query: 611 ESIASSAVRAAIKVKA-SVIICFTSSGRAARLIAKYRPTMPVLSVVIPRLKTNQLKWSFT 435
           E+IA SA+ AA  +K  + II  T SGR A + ++    +P+ +     +  ++   + T
Sbjct: 362 EAIAMSAMYAANHLKGVTAIITMTESGRTALMTSRISSGLPIFA-----MSRHERTLNLT 416

Query: 434 GAFEARQSLIVRGLFPMLADPRHPAESTSTTNESVLKVALDHGKASGVIKSHDRVVVCQ- 258
             +        RG+ P+  D  +   + ++   ++L       +  G + S D V+V Q 
Sbjct: 417 ALY--------RGVTPVHFDSANDGVAAASEAVNLL-------RDKGYLMSGDLVIVTQG 461

Query: 257 ----KVGDSSVVKIIELD 216
                VG ++  +I+ ++
Sbjct: 462 DVMSTVGSTNTTRILTVE 479



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>CRCB_XANAC (Q8PKZ5) Protein crcB homolog|
          Length = 133

 Score = 29.6 bits (65), Expect = 8.8
 Identities = 28/82 (34%), Positives = 38/82 (46%), Gaps = 4/82 (4%)
 Frame = +1

Query: 298 DALPWSRATFNT-DSFV--VLVDSAG*RGSASMGKRPLTMSDCLASNAPVK-LHFN*FVF 465
           +  PW   T N   SFV  VL+     RG +S   R L +   +        L     VF
Sbjct: 37  NVFPWGTLTVNLLGSFVAGVLLVWLDARGPSSWPLRALLIVGVIGGLTTFSSLMMECLVF 96

Query: 466 RRGMTTDRTGMVGLYLAISLAA 531
            R   TDR+ M+G+YLA++L A
Sbjct: 97  AR---TDRSTMIGIYLAVTLLA 115



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>RELB_XENLA (P51510) Transcription factor RelB homolog|
          Length = 497

 Score = 29.6 bits (65), Expect = 8.8
 Identities = 14/58 (24%), Positives = 31/58 (53%)
 Frame = -2

Query: 389 PMLADPRHPAESTSTTNESVLKVALDHGKASGVIKSHDRVVVCQKVGDSSVVKIIELD 216
           P+L+DP +  +ST+T+   + ++  ++G+  G     +  ++C KV    ++ I   D
Sbjct: 239 PVLSDPIYDKKSTNTSELKISRMNKEYGRCEG---GEEVYILCDKVQKEDILVIFGED 293


  Database: uniprot_sprot.fasta
    Posted date:  May 25, 2006  5:36 PM
  Number of letters in database: 80,573,946
  Number of sequences in database:  219,361
  
Lambda     K      H
   0.318    0.135    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 97,855,696
Number of Sequences: 219361
Number of extensions: 2002170
Number of successful extensions: 4971
Number of sequences better than 10.0: 56
Number of HSP's better than 10.0 without gapping: 4790
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4953
length of database: 80,573,946
effective HSP length: 108
effective length of database: 56,882,958
effective search space used: 6655306086
frameshift window, decay const: 50,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
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