Clone Name | rbasd18d12 |
---|---|
Clone Library Name | barley_pub |
>KPYC_TOBAC (Q42954) Pyruvate kinase, cytosolic isozyme (EC 2.7.1.40) (PK)| Length = 508 Score = 120 bits (301), Expect = 4e-27 Identities = 66/144 (45%), Positives = 88/144 (61%) Frame = -2 Query: 656 FKRTVKYVGEPMTHLESIASSAVRAAIKVKASVIICFTSSGRAARLIAKYRPTMPVLSVV 477 FKR + PM+ LES+ASSAVR A KA++I+ T G A+L+AKYRP MP+LSVV Sbjct: 363 FKRIMSNAPVPMSPLESLASSAVRTANSAKAALILVLTRGGSTAKLVAKYRPGMPILSVV 422 Query: 476 IPRLKTNQLKWSFTGAFEARQSLIVRGLFPMLADPRHPAESTSTTNESVLKVALDHGKAS 297 +P +KT+ W+ + AR SLI RGL P+L A +T E+ L AL H K Sbjct: 423 VPEIKTDSFDWTCSDESPARHSLIFRGLVPVLHAGSARASHEESTEEA-LDFALQHAKTK 481 Query: 296 GVIKSHDRVVVCQKVGDSSVVKII 225 G+ K D VV +VG +SV+KI+ Sbjct: 482 GLCKQGDSVVALHRVGTASVIKIV 505
>KPYC_SOLTU (P22200) Pyruvate kinase, cytosolic isozyme (EC 2.7.1.40) (PK)| Length = 510 Score = 115 bits (289), Expect = 9e-26 Identities = 61/148 (41%), Positives = 89/148 (60%) Frame = -2 Query: 671 NQDLYFKRTVKYVGEPMTHLESIASSAVRAAIKVKASVIICFTSSGRAARLIAKYRPTMP 492 + + FK ++ PM+ LES+ASSAVR A K +A +I+ T G A+L+AKYRP +P Sbjct: 360 DNEAIFKEMIRCTPLPMSPLESLASSAVRTANKARAKLIVVLTRGGSTAKLVAKYRPAVP 419 Query: 491 VLSVVIPRLKTNQLKWSFTGAFEARQSLIVRGLFPMLADPRHPAESTSTTNESVLKVALD 312 +LSVV+P L T+ WS + AR SL+ RGL P+L + A + +T E +L+ AL Sbjct: 420 ILSVVVPVLTTDSFDWSISDETPARHSLVYRGLIPLLGEGSAKATDSEST-EVILEAALK 478 Query: 311 HGKASGVIKSHDRVVVCQKVGDSSVVKI 228 G+ K D VV ++G +SV+KI Sbjct: 479 SAVTRGLCKPGDAVVALHRIGSASVIKI 506
>KPYC_SOYBN (Q42806) Pyruvate kinase, cytosolic isozyme (EC 2.7.1.40) (PK)| Length = 511 Score = 111 bits (278), Expect = 2e-24 Identities = 61/143 (42%), Positives = 85/143 (59%) Frame = -2 Query: 656 FKRTVKYVGEPMTHLESIASSAVRAAIKVKASVIICFTSSGRAARLIAKYRPTMPVLSVV 477 FK ++ PM+ LES+ASSAVR A K KA +I+ T G A+L+AKYRP +P+LSVV Sbjct: 366 FKEMIRSTPLPMSPLESLASSAVRTANKAKAKLIVVLTRGGSTAKLVAKYRPAVPILSVV 425 Query: 476 IPRLKTNQLKWSFTGAFEARQSLIVRGLFPMLADPRHPAESTSTTNESVLKVALDHGKAS 297 +P L T+ W+ + AR SLI RGL P+L + A +T E +L+ AL Sbjct: 426 VPVLSTDSFDWTCSDETPARHSLIYRGLIPILGEGSAKATDAEST-EVILEAALKSATER 484 Query: 296 GVIKSHDRVVVCQKVGDSSVVKI 228 + K D VV ++G +SV+KI Sbjct: 485 ALCKPGDAVVALHRIGAASVIKI 507
>KPYC_ARATH (O65595) Probable pyruvate kinase, cytosolic isozyme (EC 2.7.1.40)| (PK) Length = 497 Score = 105 bits (263), Expect = 1e-22 Identities = 57/144 (39%), Positives = 89/144 (61%) Frame = -2 Query: 656 FKRTVKYVGEPMTHLESIASSAVRAAIKVKASVIICFTSSGRAARLIAKYRPTMPVLSVV 477 FKR + + PM+ +ES+ASSAVR A +A++++ T G ARL+AKYRP +P+LSVV Sbjct: 352 FKRIMLHAAVPMSPMESLASSAVRTATSSRATLMMVLTRGGSTARLVAKYRPGIPILSVV 411 Query: 476 IPRLKTNQLKWSFTGAFEARQSLIVRGLFPMLADPRHPAESTSTTNESVLKVALDHGKAS 297 +P + ++ W+ + AR SLI RGL P+L A +T E+ L+ A ++GK Sbjct: 412 VPEITSDSFDWACSNEAPARHSLIYRGLVPVLYAGSARASIDESTEET-LEFASEYGKKK 470 Query: 296 GVIKSHDRVVVCQKVGDSSVVKII 225 + K+ D VV + G++ V+KI+ Sbjct: 471 QLCKTGDSVVALFRTGNAIVIKIL 494
>KPYK_EMENI (P22360) Pyruvate kinase (EC 2.7.1.40) (PK)| Length = 526 Score = 63.9 bits (154), Expect = 4e-10 Identities = 42/145 (28%), Positives = 71/145 (48%), Gaps = 7/145 (4%) Frame = -2 Query: 626 PMTHLESIASSAVRAAIKVKASVIICFTSSGRAARLIAKYRPTMPVLSVVIPRLKTNQLK 447 P +ESIA +AV A++++ A I+ T+SG AR+I+KYRP P++ V T Sbjct: 389 PTDTVESIAMAAVSASLELNAGAIVVLTTSGNTARMISKYRPVCPIIMVSRNPAAT---- 444 Query: 446 WSFTGAFEARQSLIVRGLFPMLADPRHPAESTSTTNESV---LKVALDHGKASGVIKSHD 276 R S + RG++P + P + E V LK ++HG G+I D Sbjct: 445 ---------RYSHLYRGVWPFYFPEKKPDFNVKIWQEDVDRRLKWGINHGLKLGIINKGD 495 Query: 275 RVVVCQ----KVGDSSVVKIIELDD 213 +V Q +G ++ V+++ ++ Sbjct: 496 NIVCVQGWRGGMGHTNTVRVVPAEE 520
>KPYK_ASPNG (Q12669) Pyruvate kinase (EC 2.7.1.40) (PK)| Length = 526 Score = 63.5 bits (153), Expect = 5e-10 Identities = 42/150 (28%), Positives = 73/150 (48%), Gaps = 7/150 (4%) Frame = -2 Query: 626 PMTHLESIASSAVRAAIKVKASVIICFTSSGRAARLIAKYRPTMPVLSVVIPRLKTNQLK 447 P +ESIA +AV A++++ A I+ T+SG+ AR ++KYRP P++ V Sbjct: 389 PTDTVESIAMAAVSASLELNAGAIVVLTTSGKTARYLSKYRPVCPIVMVT---------- 438 Query: 446 WSFTGAFEARQSLIVRGLFPMLADPRHPAESTSTTNESV---LKVALDHGKASGVIKSHD 276 +R S + RG++P L + P + E V LK ++H G+I D Sbjct: 439 ---RNPAASRYSHLYRGVWPFLFPEKKPDFNVKVWQEDVDRRLKWGINHALKLGIINKGD 495 Query: 275 RVVVCQ----KVGDSSVVKIIELDD*AKLA 198 +V Q +G ++ V+++ ++ LA Sbjct: 496 NIVCVQGWRGGMGHTNTVRVVPAEENLGLA 525
>KPYK_NEUCR (Q7RVA8) Pyruvate kinase (EC 2.7.1.40) (PK)| Length = 527 Score = 62.8 bits (151), Expect = 9e-10 Identities = 42/155 (27%), Positives = 76/155 (49%), Gaps = 7/155 (4%) Frame = -2 Query: 659 YFKRTVKYVGEPMTHLESIASSAVRAAIKVKASVIICFTSSGRAARLIAKYRPTMPVLSV 480 +F+ P++ +ES A ++VRA++ + A+ I+ ++SG +ARLI+KYRP P++ + Sbjct: 377 HFEELCSLAKRPVSIVESCAMASVRASLDLNAAAILVLSTSGESARLISKYRPVCPIIMI 436 Query: 479 VIPRLKTNQLKWSFTGAFEARQSLIVRGLFPMLADPRHPAESTSTTNESV---LKVALDH 309 +R + + RG++P L P S E V +K L H Sbjct: 437 T-------------RNDSASRYAHLYRGVYPFLFPESKPDFSKVNWQEDVDRRIKWGLSH 483 Query: 308 GKASGVIKSHDRVVVCQ----KVGDSSVVKIIELD 216 G V+ + VVV Q +G+++ +I++ D Sbjct: 484 GIGLKVLNEGETVVVVQGWKGGMGNTNTFRIVKAD 518
>KPYK_XENLA (Q92122) Pyruvate kinase muscle isozyme (EC 2.7.1.40) (Cytosolic| thyroid hormone-binding protein) (CTHBP) Length = 527 Score = 62.4 bits (150), Expect = 1e-09 Identities = 42/117 (35%), Positives = 62/117 (52%), Gaps = 1/117 (0%) Frame = -2 Query: 611 ESIASSAVRAAIKVKASVIICFTSSGRAARLIAKYRPTMPVLSVVIPRLKTNQLKWSFTG 432 E+ A AV A+ K + II T SGR+A L+++YRP P++SV Sbjct: 406 EATAVGAVEASFKCSSGAIIVLTKSGRSAHLLSRYRPRAPIISVT-------------RN 452 Query: 431 AFEARQSLIVRGLFPML-ADPRHPAESTSTTNESVLKVALDHGKASGVIKSHDRVVV 264 ARQ+ + RG+FP+L + H E+ + +S + A+D GKA G KS D V+V Sbjct: 453 GQTARQAHLYRGIFPVLYREAVH--EAWAEDVDSRVNFAMDIGKARGFFKSGDVVIV 507
>KPYK_YARLI (P30614) Pyruvate kinase (EC 2.7.1.40) (PK)| Length = 515 Score = 60.5 bits (145), Expect = 5e-09 Identities = 46/142 (32%), Positives = 71/142 (50%), Gaps = 7/142 (4%) Frame = -2 Query: 626 PMTHLESIASSAVRAAIKVKASVIICFTSSGRAARLIAKYRPTMPVLSVVIPRLKTNQLK 447 P +E+IA SAV A+ + +A II ++SG +ARL +KYRP P+L V Sbjct: 386 PTETVETIAISAVSASFEQQARAIIVLSTSGTSARLCSKYRPNCPILMVT---------- 435 Query: 446 WSFTGAFEARQSLIVRGLFPML---ADPRHPAESTSTTNESVLKVALDHGKASGVIKSHD 276 A AR S + RG++P + A +PAE E LK +D A G++ D Sbjct: 436 ---RNAQAARFSHLYRGVYPFIYHKARASNPAEWQHDVEER-LKWGMDEAVALGILNKGD 491 Query: 275 RVVVCQ----KVGDSSVVKIIE 222 VV Q +G ++ ++++E Sbjct: 492 VVVAIQGWTGGLGHTNTLRVLE 513
>KPYK_CHICK (P00548) Pyruvate kinase muscle isozyme (EC 2.7.1.40)| Length = 529 Score = 60.1 bits (144), Expect = 6e-09 Identities = 38/117 (32%), Positives = 66/117 (56%), Gaps = 1/117 (0%) Frame = -2 Query: 611 ESIASSAVRAAIKVKASVIICFTSSGRAARLIAKYRPTMPVLSVVIPRLKTNQLKWSFTG 432 +++A+ AV A+ K A+ +I T SGR+A L+++YRP P+++V + +Q Sbjct: 408 DAMAAGAVEASFKCLAAALIVMTESGRSAHLVSRYRPRAPIIAVT----RNDQ------- 456 Query: 431 AFEARQSLIVRGLFPMLA-DPRHPAESTSTTNESVLKVALDHGKASGVIKSHDRVVV 264 ARQ+ + RG+FP+L P H A + + + + ++ GKA G K+ D V+V Sbjct: 457 --TARQAHLYRGVFPVLCKQPAHDAWAEDV--DLRVNLGMNVGKARGFFKTGDLVIV 509
>KPYK2_CANGA (Q6FV12) Pyruvate kinase 2 (EC 2.7.1.40) (PK 2)| Length = 508 Score = 60.1 bits (144), Expect = 6e-09 Identities = 42/139 (30%), Positives = 72/139 (51%), Gaps = 5/139 (3%) Frame = -2 Query: 629 EPMTHLESIASSAVRAAIKVKASVIICFTSSGRAARLIAKYRPTMPVLSVV-IPRLKTNQ 453 +P + E++A+SAV A + A +I+ ++SG ARL++KYRP P++ V PR Sbjct: 375 KPTSTTETVAASAVAAVQEQGAKLILVLSTSGNTARLVSKYRPQCPIVLVTRNPR----- 429 Query: 452 LKWSFTGAFEARQSLIVRGLFPMLADPRHPAESTSTTNESVLKVALDHGKASGVIKSHDR 273 AR S + RG+FP + + + P + S + L+ +D K G +K+ D Sbjct: 430 ---------TARFSHLFRGVFPFVYE-KEPLDDWSEDTHARLRFGVDMAKEYGFVKNGDA 479 Query: 272 VVVCQ----KVGDSSVVKI 228 V+ Q VG S+ +++ Sbjct: 480 VISIQGFKGGVGHSNTMRV 498
>KPYK1_CANGA (Q6FIS9) Pyruvate kinase 1 (EC 2.7.1.40) (PK 1)| Length = 501 Score = 58.9 bits (141), Expect = 1e-08 Identities = 41/138 (29%), Positives = 68/138 (49%), Gaps = 4/138 (2%) Frame = -2 Query: 629 EPMTHLESIASSAVRAAIKVKASVIICFTSSGRAARLIAKYRPTMPVLSVVIPRLKTNQL 450 +P + E++A+SAV A + KA II ++SG ARL++KYRP P++ V Sbjct: 375 KPTSTTETVAASAVAAVFEQKAKAIIVLSTSGTTARLVSKYRPNCPIILVT--------- 425 Query: 449 KWSFTGAFEARQSLIVRGLFPMLADPRHPAESTSTTNESVLKVALDHGKASGVIKSHDRV 270 A AR S + RG+FP + + ++ T E+ L ++ G++K D Sbjct: 426 ----RNARTARFSHLYRGVFPFVYEKESVSDWTEDV-EARLNFGIEQAIEFGILKKGDTY 480 Query: 269 VVCQ----KVGDSSVVKI 228 V Q VG S+ +++ Sbjct: 481 VSIQGFKAGVGHSNTLQV 498
>KPYK_TRIRE (P31865) Pyruvate kinase (EC 2.7.1.40) (PK)| Length = 538 Score = 58.9 bits (141), Expect = 1e-08 Identities = 44/155 (28%), Positives = 75/155 (48%), Gaps = 7/155 (4%) Frame = -2 Query: 659 YFKRTVKYVGEPMTHLESIASSAVRAAIKVKASVIICFTSSGRAARLIAKYRPTMPVLSV 480 +F+ V P++ +ES A +AVRA++ + A II ++SG +ARL++KYRP P+ V Sbjct: 387 HFEEMCTLVKRPVSTVESCAMAAVRASLDLGAGGIIVLSTSGDSARLLSKYRPVCPIFMV 446 Query: 479 VIPRLKTNQLKWSFTGAFEARQSLIVRGLFPMLADPRHPAESTSTTNESV---LKVALDH 309 +R S + RG++P L + P T E V +K A+ Sbjct: 447 T-------------RNPTTSRFSHLYRGVYPFLYPEQKPDFDTVNWQEDVDKRIKWAVTR 493 Query: 308 GKASGVIKSHDRVVVCQ----KVGDSSVVKIIELD 216 + + D VVV Q +G+++ ++I+ D Sbjct: 494 AIELKTLTAGDTVVVVQGWKGGMGNTNTLRIVRAD 528
>KPYK1_YEAST (P00549) Pyruvate kinase 1 (EC 2.7.1.40) (PK 1)| Length = 500 Score = 58.5 bits (140), Expect = 2e-08 Identities = 38/125 (30%), Positives = 62/125 (49%), Gaps = 1/125 (0%) Frame = -2 Query: 629 EPMTHLESIASSAVRAAIKVKASVIICFTSSGRAARLIAKYRPTMPVLSVV-IPRLKTNQ 453 +P + E++A+SAV A + KA II ++SG RL++KYRP P++ V PR Sbjct: 374 KPTSTTETVAASAVAAVFEQKAKAIIVLSTSGTTPRLVSKYRPNCPIILVTRCPR----- 428 Query: 452 LKWSFTGAFEARQSLIVRGLFPMLADPRHPAESTSTTNESVLKVALDHGKASGVIKSHDR 273 AR S + RG+FP + + + P + E+ + ++ K G++K D Sbjct: 429 ---------AARFSHLYRGVFPFVFE-KEPVSDWTDDVEARINFGIEKAKEFGILKKGDT 478 Query: 272 VVVCQ 258 V Q Sbjct: 479 YVSIQ 483
>KPYM_RAT (P11980) Pyruvate kinase isozymes M1/M2 (EC 2.7.1.40) (Pyruvate| kinase muscle isozyme) Length = 530 Score = 57.4 bits (137), Expect = 4e-08 Identities = 38/133 (28%), Positives = 66/133 (49%) Frame = -2 Query: 662 LYFKRTVKYVGEPMTHLESIASSAVRAAIKVKASVIICFTSSGRAARLIAKYRPTMPVLS 483 L F+ + + LE++A +V A+ K A+ +I T SGR+A +A+YRP P+++ Sbjct: 392 LLFEELARASSQSTDPLEAMAMGSVEASYKCLAAALIVLTESGRSAHQVARYRPRAPIIA 451 Query: 482 VVIPRLKTNQLKWSFTGAFEARQSLIVRGLFPMLADPRHPAESTSTTNESVLKVALDHGK 303 V ARQ+ + RG+FP+L ++ + + + +A++ GK Sbjct: 452 VT-------------RNPQTARQAHLYRGIFPVLCKDA-VLDAWAEDVDLRVNLAMNVGK 497 Query: 302 ASGVIKSHDRVVV 264 A G K D V+V Sbjct: 498 ARGFFKKGDVVIV 510
>KPYM_PONPY (Q5NVN0) Pyruvate kinase isozyme M1 (EC 2.7.1.40)| Length = 530 Score = 57.4 bits (137), Expect = 4e-08 Identities = 40/132 (30%), Positives = 66/132 (50%), Gaps = 1/132 (0%) Frame = -2 Query: 656 FKRTVKYVGEPMTHLESIASSAVRAAIKVKASVIICFTSSGRAARLIAKYRPTMPVLSVV 477 F+ V+ +E++A +V A+ K A+ +I T SGR+A +A+YRP P+++V Sbjct: 394 FEELVRASSHSTDLMEAMAMGSVEASYKCLAAALIVLTESGRSAHQVARYRPRAPIIAVT 453 Query: 476 IPRLKTNQLKWSFTGAFEARQSLIVRGLFPMLA-DPRHPAESTSTTNESVLKVALDHGKA 300 ARQ+ + RG+FP+L DP E+ + + + A++ GKA Sbjct: 454 -------------RNPQTARQAHLYRGIFPVLCKDP--VQEAWAEDVDLRVNFAMNVGKA 498 Query: 299 SGVIKSHDRVVV 264 G K D V+V Sbjct: 499 RGFFKKGDVVIV 510
>KPYK_SACKL (Q875S4) Pyruvate kinase (EC 2.7.1.40) (PK)| Length = 501 Score = 57.4 bits (137), Expect = 4e-08 Identities = 41/143 (28%), Positives = 72/143 (50%), Gaps = 5/143 (3%) Frame = -2 Query: 638 YVGEPMTHLESIASSAVRAAIKVKASVIICFTSSGRAARLIAKYRPTMPVLSVV-IPRLK 462 + +P + E+IA++AV + + KA II +++G RL++KY+P +P++ V PR Sbjct: 372 FTPKPTSTTETIAAAAVSSVFEQKAKAIIVLSTTGDTPRLVSKYKPNVPIVMVTRNPR-- 429 Query: 461 TNQLKWSFTGAFEARQSLIVRGLFPMLADPRHPAESTSTTNESVLKVALDHGKASGVIKS 282 AR S + RG+FP + + +E T ES L + K G++K Sbjct: 430 ------------AARFSHLYRGVFPFVYESDTESEWTKDV-ESRLNFGIAKAKEFGMLKE 476 Query: 281 HDRVVVCQ----KVGDSSVVKII 225 D +V Q VG S+ ++++ Sbjct: 477 GDTIVTIQGFAAGVGHSNTLRVL 499
>KPYM_RABIT (P11974) Pyruvate kinase isozymes M1/M2 (EC 2.7.1.40) (Pyruvate| kinase muscle isozyme) Length = 530 Score = 57.0 bits (136), Expect = 5e-08 Identities = 38/118 (32%), Positives = 66/118 (55%), Gaps = 1/118 (0%) Frame = -2 Query: 614 LESIASSAVRAAIKVKASVIICFTSSGRAARLIAKYRPTMPVLSVVIPRLKTNQLKWSFT 435 +E++A +V A+ K A+ +I T SGR+A +A+YRP P+++V + +Q Sbjct: 408 MEAMAMGSVEASYKCLAAALIVLTESGRSAHQVARYRPRAPIIAVT----RNHQ------ 457 Query: 434 GAFEARQSLIVRGLFPMLA-DPRHPAESTSTTNESVLKVALDHGKASGVIKSHDRVVV 264 ARQ+ + RG+FP++ DP E+ + + + +A++ GKA G K D V+V Sbjct: 458 ---TARQAHLYRGIFPVVCKDP--VQEAWAEDVDLRVNLAMNVGKARGFFKKGDVVIV 510
>KPYM_FELCA (P11979) Pyruvate kinase isozyme M1 (EC 2.7.1.40) (Pyruvate kinase| muscle isozyme) Length = 530 Score = 57.0 bits (136), Expect = 5e-08 Identities = 40/132 (30%), Positives = 70/132 (53%), Gaps = 1/132 (0%) Frame = -2 Query: 656 FKRTVKYVGEPMTHLESIASSAVRAAIKVKASVIICFTSSGRAARLIAKYRPTMPVLSVV 477 F+ V+ +E++A +V A+ K A+ +I T SGR+A +A+YRP P+++V Sbjct: 394 FEELVRGSSHSTDLMEAMAMGSVEASYKCLAAALIVLTESGRSAHQVARYRPRAPIIAVT 453 Query: 476 IPRLKTNQLKWSFTGAFEARQSLIVRGLFPMLA-DPRHPAESTSTTNESVLKVALDHGKA 300 + +Q ARQ+ + RG+FP++ DP E+ + + + +A++ GKA Sbjct: 454 ----RNHQ---------TARQAHLYRGIFPVVCKDP--VQEAWAEDVDLRVNLAMNVGKA 498 Query: 299 SGVIKSHDRVVV 264 G K D V+V Sbjct: 499 RGFFKHGDVVIV 510
>KPYK_DROME (O62619) Pyruvate kinase (EC 2.7.1.40) (PK)| Length = 533 Score = 57.0 bits (136), Expect = 5e-08 Identities = 43/134 (32%), Positives = 70/134 (52%), Gaps = 5/134 (3%) Frame = -2 Query: 602 ASSAVRAAIKVKASVIICFTSSGRAARLIAKYRPTMPVLSVVIPRLKTNQLKWSFTGAFE 423 A +AV AA K KAS I+ T+SG++A ++KYRP P+++V A Sbjct: 415 AIAAVEAATKAKASAIVVITTSGKSAFQVSKYRPRCPIIAVT-------------RFAQT 461 Query: 422 ARQSLIVRGLFPMLADPRHPAESTSTTNESV-LKVALDHGKASGVIKSHDRVVVC----Q 258 ARQ+ + RGL P++ + P + V ++ L GK +G IK+ D VVV Q Sbjct: 462 ARQAHLYRGLVPLIY--KEPGLGDWLKDVDVRVQFGLQVGKKNGFIKTGDSVVVVTGWKQ 519 Query: 257 KVGDSSVVKIIELD 216 G ++ ++I+ ++ Sbjct: 520 GSGFTNTIRIVTVE 533
>KPYK2_TRYBB (P30616) Pyruvate kinase 2 (EC 2.7.1.40) (PK 2)| Length = 499 Score = 55.8 bits (133), Expect = 1e-07 Identities = 39/121 (32%), Positives = 60/121 (49%) Frame = -2 Query: 626 PMTHLESIASSAVRAAIKVKASVIICFTSSGRAARLIAKYRPTMPVLSVVIPRLKTNQLK 447 PM E++ SSAV +A +V+A ++ +++GR+ARLI+KYRP P++ V RL+T Sbjct: 374 PMCPEEAVCSSAVASAFEVQAKAMLVLSNTGRSARLISKYRPNCPIICVT-TRLQT---- 428 Query: 446 WSFTGAFEARQSLIVRGLFPMLADPRHPAESTSTTNESVLKVALDHGKASGVIKSHDRVV 267 RQ + R + + D E E +K+ LD K + D VV Sbjct: 429 --------CRQLNVTRSVVSVFYDAAKSGEDKD--KEKRVKLGLDFAKKEKYASTGDVVV 478 Query: 266 V 264 V Sbjct: 479 V 479
>KPYK1_TRYBB (P30615) Pyruvate kinase 1 (EC 2.7.1.40) (PK 1)| Length = 499 Score = 55.8 bits (133), Expect = 1e-07 Identities = 39/121 (32%), Positives = 60/121 (49%) Frame = -2 Query: 626 PMTHLESIASSAVRAAIKVKASVIICFTSSGRAARLIAKYRPTMPVLSVVIPRLKTNQLK 447 PM E++ SSAV +A +V+A ++ +++GR+ARLI+KYRP P++ V RL+T Sbjct: 374 PMCPEEAVCSSAVASAFEVQAKAMLVLSNTGRSARLISKYRPNCPIICVT-TRLQT---- 428 Query: 446 WSFTGAFEARQSLIVRGLFPMLADPRHPAESTSTTNESVLKVALDHGKASGVIKSHDRVV 267 RQ + R + + D E E +K+ LD K + D VV Sbjct: 429 --------CRQLNVTRSVVSVFYDAAKSGEDKD--KEKRVKLGLDFAKKEKYASTGDVVV 478 Query: 266 V 264 V Sbjct: 479 V 479
>KPYM_MOUSE (P52480) Pyruvate kinase isozyme M2 (EC 2.7.1.40)| Length = 530 Score = 55.1 bits (131), Expect = 2e-07 Identities = 40/118 (33%), Positives = 58/118 (49%), Gaps = 2/118 (1%) Frame = -2 Query: 611 ESIASSAVRAAIKVKASVIICFTSSGRAARLIAKYRPTMPVLSVVIPRLKTNQLKWSFTG 432 E+ A AV A+ K + II T SGR+A +A+YRP P+++V Sbjct: 409 EAAAVGAVEASFKCCSGAIIVLTKSGRSAHQVARYRPRAPIIAVT-------------RN 455 Query: 431 AFEARQSLIVRGLFPMLADPRHPAESTSTTNESVLKV--ALDHGKASGVIKSHDRVVV 264 ARQ+ + RG+FP+L A + + L+V A+D GKA G K D V+V Sbjct: 456 PQTARQAHLYRGIFPVLC---KDAVLNAWAEDVDLRVNLAMDVGKARGFFKKGDVVIV 510
>KPYM_HUMAN (P14618) Pyruvate kinase isozymes M1/M2 (EC 2.7.1.40) (Pyruvate| kinase muscle isozyme) (Cytosolic thyroid hormone-binding protein) (CTHBP) (THBP1) Length = 530 Score = 55.1 bits (131), Expect = 2e-07 Identities = 39/117 (33%), Positives = 59/117 (50%), Gaps = 1/117 (0%) Frame = -2 Query: 611 ESIASSAVRAAIKVKASVIICFTSSGRAARLIAKYRPTMPVLSVVIPRLKTNQLKWSFTG 432 E+ A AV A+ K + II T SGR+A +A+YRP P+++V Sbjct: 409 EATAVGAVEASFKCCSGAIIVLTKSGRSAHQVARYRPRAPIIAVT-------------RN 455 Query: 431 AFEARQSLIVRGLFPMLA-DPRHPAESTSTTNESVLKVALDHGKASGVIKSHDRVVV 264 ARQ+ + RG+FP+L DP E+ + + + A++ GKA G K D V+V Sbjct: 456 PQTARQAHLYRGIFPVLCKDP--VQEAWAEDVDLRVNFAMNVGKARGFFKKGDVVIV 510
>KPYK_EIMTE (O44006) Pyruvate kinase (EC 2.7.1.40) (PK)| Length = 531 Score = 55.1 bits (131), Expect = 2e-07 Identities = 39/152 (25%), Positives = 71/152 (46%), Gaps = 5/152 (3%) Frame = -2 Query: 656 FKRTVKYVGEPMTHLESIASSAVRAAIKVKASVIICFTSSGRAARLIAKYRPTMPVLSVV 477 F+ T + P+ E++A +AV A + AS+I+ T +GR ARLIAKYRP P+L++ Sbjct: 400 FRATCQATMTPIDTQEAVARAAVETAQSINASLILALTETGRTARLIAKYRPMQPILALS 459 Query: 476 IPRLKTNQLKWSFTGAFEARQSLIVRGLFPMLADPRHPAESTSTTNESVLKVALDHGKAS 297 QL+ ++RG+ L T + +++ AL K Sbjct: 460 ASEETIKQLQ-------------VIRGVTTFLV-------PTFQGTDQLIRNALSAAKEL 499 Query: 296 GVIKSHDRVVVCQKV-----GDSSVVKIIELD 216 ++ D +V + G S+++K++ ++ Sbjct: 500 QLVSEGDSIVAVHGIKEEVAGWSNLLKVLVVE 531
>KPYK_KLULA (Q875M9) Pyruvate kinase (EC 2.7.1.40) (PK)| Length = 501 Score = 55.1 bits (131), Expect = 2e-07 Identities = 39/140 (27%), Positives = 70/140 (50%), Gaps = 5/140 (3%) Frame = -2 Query: 629 EPMTHLESIASSAVRAAIKVKASVIICFTSSGRAARLIAKYRPTMPVLSVV-IPRLKTNQ 453 +P + E+IA+++V A + KA +I +++G RL+AKY+P +P++ V PR Sbjct: 375 KPTSTTETIAAASVSAVFEQKARALIVLSTTGDTPRLVAKYKPNVPIVMVTRNPR----- 429 Query: 452 LKWSFTGAFEARQSLIVRGLFPMLADPRHPAESTSTTNESVLKVALDHGKASGVIKSHDR 273 AR S + RG+FP + D +E T E + + K G++ D Sbjct: 430 ---------AARFSHLYRGVFPFVYDESSDSEWTVDV-EKRINFGVKKAKEFGILVDGDT 479 Query: 272 VVVCQ----KVGDSSVVKII 225 +V Q VG+S+ ++++ Sbjct: 480 IVTIQGFAAGVGNSNTLRVL 499
>KPYK_SACCA (Q875Z9) Pyruvate kinase (EC 2.7.1.40) (PK)| Length = 501 Score = 54.7 bits (130), Expect = 3e-07 Identities = 41/125 (32%), Positives = 61/125 (48%), Gaps = 1/125 (0%) Frame = -2 Query: 629 EPMTHLESIASSAVRAAIKVKASVIICFTSSGRAARLIAKYRPTMPVLSVV-IPRLKTNQ 453 +P + E++A+SAV A + KA II ++SG RL++KYRP P++ V PR Sbjct: 375 KPTSTTETVAASAVAAVYEQKAKAIIVLSTSGTTPRLVSKYRPDCPIILVTRNPR----- 429 Query: 452 LKWSFTGAFEARQSLIVRGLFPMLADPRHPAESTSTTNESVLKVALDHGKASGVIKSHDR 273 AR S + RG+FP + + A+ T E LK ++ GV+K D Sbjct: 430 ---------AARFSHLSRGVFPFVYEADSVADWTEDV-ELRLKFGIEKAIEMGVMKKGDT 479 Query: 272 VVVCQ 258 V Q Sbjct: 480 YVSIQ 484
>KPYK_ASHGO (Q759A9) Pyruvate kinase (EC 2.7.1.40) (PK)| Length = 501 Score = 54.7 bits (130), Expect = 3e-07 Identities = 38/140 (27%), Positives = 70/140 (50%), Gaps = 5/140 (3%) Frame = -2 Query: 629 EPMTHLESIASSAVRAAIKVKASVIICFTSSGRAARLIAKYRPTMPVLSVV-IPRLKTNQ 453 +P E+IA++AV A + KA I+ ++SG RL++KY+P +P++ V PR Sbjct: 375 KPTPTSETIAAAAVAATFEQKAKAIVVLSTSGDTTRLVSKYKPNVPIVMVTRNPR----- 429 Query: 452 LKWSFTGAFEARQSLIVRGLFPMLADPRHPAESTSTTNESVLKVALDHGKASGVIKSHDR 273 AR + RG+FP + + + A+ + E+ L ++ K G++ D Sbjct: 430 ---------AARYCHLHRGVFPFVYE-QEAADEWTDDVEARLNFGVEKSKELGILSEGDT 479 Query: 272 VVVCQ----KVGDSSVVKII 225 +V Q VG S+ ++++ Sbjct: 480 IVTIQGFASGVGHSNTLRVL 499
>KPYK_BACSU (P80885) Pyruvate kinase (EC 2.7.1.40) (PK) (Vegetative protein 17)| (VEG17) Length = 585 Score = 53.9 bits (128), Expect = 4e-07 Identities = 38/136 (27%), Positives = 68/136 (50%), Gaps = 1/136 (0%) Frame = -2 Query: 623 MTHLESIASSAVRAAIKVKASVIICFTSSGRAARLIAKYRPTMPVLSVVIPRLKTNQLKW 444 MT ++I S AI + A+ I+ T SG AR+IAKYRP P+++V + Sbjct: 354 MTITDAIGQSVAHTAINLNAAAIVTPTESGHTARMIAKYRPQAPIVAVTV---------- 403 Query: 443 SFTGAFEARQSLIVRGLFPMLADPRHPAESTSTTNESVLKVALDHGKASGVIKSHDRVVV 264 +R+ +V G+F ++ S+T+E +L+ A+ SG++K D +V+ Sbjct: 404 ---NDSISRKLALVSGVF------AESGQNASSTDE-MLEDAVQKSLNSGIVKHGDLIVI 453 Query: 263 -CQKVGDSSVVKIIEL 219 VG+S ++++ Sbjct: 454 TAGTVGESGTTNLMKV 469
>KPYK2_YEAST (P52489) Pyruvate kinase 2 (EC 2.7.1.40) (PK 2)| Length = 506 Score = 53.5 bits (127), Expect = 6e-07 Identities = 36/138 (26%), Positives = 70/138 (50%), Gaps = 4/138 (2%) Frame = -2 Query: 629 EPMTHLESIASSAVRAAIKVKASVIICFTSSGRAARLIAKYRPTMPVLSVVIPRLKTNQL 450 +P + E++A++A A ++ I+ +++G ARL++KYRP+ P++ V Sbjct: 376 KPTSTTETVAAAATAAILEQDGKAIVVLSTTGNTARLLSKYRPSCPIILVT--------- 426 Query: 449 KWSFTGAFEARQSLIVRGLFPMLADPRHPAESTSTTNESVLKVALDHGKASGVIKSHDRV 270 A AR + + RG+FP L +P+ + + LK ++ ++ G++ + D V Sbjct: 427 ----RHARTARIAHLYRGVFPFLYEPKRLDDWGEDVHRR-LKFGVEMARSFGMVDNGDTV 481 Query: 269 VVCQ----KVGDSSVVKI 228 V Q VG S+ ++I Sbjct: 482 VSIQGFKGGVGHSNTLRI 499
>KPYR_HUMAN (P30613) Pyruvate kinase isozymes R/L (EC 2.7.1.40) (R-type/L-type| pyruvate kinase) (Red cell/liver pyruvate kinase) Length = 574 Score = 53.1 bits (126), Expect = 7e-07 Identities = 38/117 (32%), Positives = 61/117 (52%), Gaps = 1/117 (0%) Frame = -2 Query: 611 ESIASSAVRAAIKVKASVIICFTSSGRAARLIAKYRPTMPVLSVVIPRLKTNQLKWSFTG 432 E A AV AA K A+ II T++GR+A+L+++YRP V++V Sbjct: 453 EVTAIGAVEAAFKCCAAAIIVLTTTGRSAQLLSRYRPRAAVIAVT-------------RS 499 Query: 431 AFEARQSLIVRGLFPMLADPRHPAESTSTTN-ESVLKVALDHGKASGVIKSHDRVVV 264 A ARQ + RG+FP+L R P E+ + + ++ ++ GK G ++ D V+V Sbjct: 500 AQAARQVHLCRGVFPLLY--REPPEAIWADDVDRRVQFGIESGKLRGFLRVGDLVIV 554
>KPYR_MOUSE (P53657) Pyruvate kinase isozymes R/L (EC 2.7.1.40) (L-PK)| Length = 574 Score = 51.6 bits (122), Expect = 2e-06 Identities = 37/117 (31%), Positives = 60/117 (51%), Gaps = 1/117 (0%) Frame = -2 Query: 611 ESIASSAVRAAIKVKASVIICFTSSGRAARLIAKYRPTMPVLSVVIPRLKTNQLKWSFTG 432 E A AV A+ K A+ II T +GR+A+L+++YRP V++V Sbjct: 453 EVTAIGAVEASFKCCAAAIIVLTKTGRSAQLLSRYRPRAAVIAVT-------------RS 499 Query: 431 AFEARQSLIVRGLFPMLADPRHPAESTSTTN-ESVLKVALDHGKASGVIKSHDRVVV 264 A ARQ + RG+FP+L R P E+ + + ++ ++ GK G ++ D V+V Sbjct: 500 AQAARQVHLSRGVFPLLY--REPPEAVWADDVDRRVQFGIESGKLRGFLRVGDLVIV 554
>KPYR_CANFA (Q29536) Pyruvate kinase isozyme R (EC 2.7.1.40) (Fragment)| Length = 519 Score = 51.2 bits (121), Expect = 3e-06 Identities = 36/117 (30%), Positives = 61/117 (52%), Gaps = 1/117 (0%) Frame = -2 Query: 611 ESIASSAVRAAIKVKASVIICFTSSGRAARLIAKYRPTMPVLSVVIPRLKTNQLKWSFTG 432 E A + V AA K A+ II T +GR+A+L+++YRP V++V Sbjct: 398 EVTAIATVEAAFKCCAAAIIVLTKTGRSAQLLSRYRPRAAVIAVT-------------RS 444 Query: 431 AFEARQSLIVRGLFPML-ADPRHPAESTSTTNESVLKVALDHGKASGVIKSHDRVVV 264 A ARQ+ + RG+FP+L ++P P + + ++ ++ GK G ++ D V+V Sbjct: 445 AQAARQAHLCRGVFPLLYSEP--PEAIWADDVDRRVQFGIESGKLRGFLRVGDLVIV 499
>KPYR_RAT (P12928) Pyruvate kinase isozymes R/L (EC 2.7.1.40) (L-PK)| Length = 574 Score = 50.8 bits (120), Expect = 4e-06 Identities = 37/117 (31%), Positives = 60/117 (51%), Gaps = 1/117 (0%) Frame = -2 Query: 611 ESIASSAVRAAIKVKASVIICFTSSGRAARLIAKYRPTMPVLSVVIPRLKTNQLKWSFTG 432 E A AV A+ K A+ II T +GR+A+L+++YRP V++V Sbjct: 453 EVTAIGAVEASFKCCAAAIIVLTKTGRSAQLLSQYRPRAAVIAVT-------------RS 499 Query: 431 AFEARQSLIVRGLFPMLADPRHPAESTSTTN-ESVLKVALDHGKASGVIKSHDRVVV 264 A ARQ + RG+FP+L R P E+ + + ++ ++ GK G ++ D V+V Sbjct: 500 AQAARQVHLSRGVFPLLY--REPPEAIWADDVDRRVQFGIESGKLRGFLRVGDLVIV 554
>KPYK_TRYBO (Q27788) Pyruvate kinase (EC 2.7.1.40) (PK)| Length = 498 Score = 50.4 bits (119), Expect = 5e-06 Identities = 36/120 (30%), Positives = 57/120 (47%) Frame = -2 Query: 626 PMTHLESIASSAVRAAIKVKASVIICFTSSGRAARLIAKYRPTMPVLSVVIPRLKTNQLK 447 P+ E+I SSAV + ++ A I+ T++GR+A +++KYRP +P++ + +L Sbjct: 373 PLIPEEAICSSAVNSIFELHAKAILVLTNTGRSAHMVSKYRPPVPIICA------SQELD 426 Query: 446 WSFTGAFEARQSLIVRGLFPMLADPRHPAESTSTTNESVLKVALDHGKASGVIKSHDRVV 267 R I RG P+ D E + +A+D GK GV K D VV Sbjct: 427 -------VCRLLSITRGTIPVYYDTEKLGPDYD--REKRVGLAIDVGKQMGVFKEGDVVV 477
>KPYK_SCHPO (Q10208) Pyruvate kinase (EC 2.7.1.40) (PK)| Length = 509 Score = 50.1 bits (118), Expect = 6e-06 Identities = 35/133 (26%), Positives = 64/133 (48%), Gaps = 2/133 (1%) Frame = -2 Query: 611 ESIASSAVRAAIKVKASVIICFTSSGRAARLIAKYRPTMPVLSVV-IPRLKTNQLKWSFT 435 E+ A +A+ A+I+ A I+ ++SG ARL +KYRP++P++ V P+ Sbjct: 388 ETTAVAAIGASIESDAKAIVVLSTSGNTARLCSKYRPSIPIVMVTRCPQ----------- 436 Query: 434 GAFEARQSLIVRGLFPMLADPRHPAESTSTTNESVLKVALDHGKASGVIKSHDRVVVCQ- 258 ARQS + RG++P++ + + P ++ + ++K D+++V Q Sbjct: 437 ---RARQSHLNRGVYPVIYE-KEPLSDWQKDVDARVAYGCQQAYKMNILKKGDKIIVLQG 492 Query: 257 KVGDSSVVKIIEL 219 VG I L Sbjct: 493 AVGGKGHTSIFRL 505
>KPYK_LEIME (Q27686) Pyruvate kinase (EC 2.7.1.40) (PK)| Length = 499 Score = 49.7 bits (117), Expect = 8e-06 Identities = 36/136 (26%), Positives = 63/136 (46%) Frame = -2 Query: 671 NQDLYFKRTVKYVGEPMTHLESIASSAVRAAIKVKASVIICFTSSGRAARLIAKYRPTMP 492 N+ ++F K PM+ E++ SAV + + KA ++ +++G ARL+AKYRP P Sbjct: 359 NEYVFFNSIKKLQHIPMSADEAVCGSAVNSVSETKAKAMVVLSNTGAGARLVAKYRPNCP 418 Query: 491 VLSVVIPRLKTNQLKWSFTGAFEARQSLIVRGLFPMLADPRHPAESTSTTNESVLKVALD 312 ++ V RL+T RQ I +G+ + D E + ++ Sbjct: 419 IVCVT-TRLQT------------CRQLNITQGVESVFFDADKLGHDEG--KEHRVAAGVE 463 Query: 311 HGKASGVIKSHDRVVV 264 K+ G +++ D VV Sbjct: 464 FAKSKGYVQTGDYCVV 479
>KPYK_LACDE (P34038) Pyruvate kinase (EC 2.7.1.40) (PK)| Length = 589 Score = 49.3 bits (116), Expect = 1e-05 Identities = 45/150 (30%), Positives = 71/150 (47%), Gaps = 2/150 (1%) Frame = -2 Query: 662 LYFKRTVKYVGEPMTHLESIASSAVRAAIKVKASVIICFTSSGRAARLIAKYRPTMPVLS 483 L +R +Y G +T E+I S VR A ++ II TSSG AR+I+KYRP +++ Sbjct: 346 LALQRFEEYKGSNVT--EAIGESVVRTAQELGVKTIIAATSSGYTARMISKYRPDATIVA 403 Query: 482 VVIPRLKTNQLKWSFTGAFEARQSLIVRGLFPMLADPRHPAESTSTTNESVLKVALDHGK 303 + + L IV G+ P+LA + P+ +T E +VA +H Sbjct: 404 LTFDEKIQHSLG-------------IVWGVEPVLA--KKPS-NTDEMFEEAARVAKEH-- 445 Query: 302 ASGVIKSHDRVVVCQKV--GDSSVVKIIEL 219 G +K D V++ V G S +++L Sbjct: 446 --GFVKDGDLVIIVAGVPFGQSGTTNLMKL 473
>KPYK_BACST (Q02499) Pyruvate kinase (EC 2.7.1.40) (PK)| Length = 587 Score = 48.5 bits (114), Expect = 2e-05 Identities = 43/168 (25%), Positives = 81/168 (48%), Gaps = 5/168 (2%) Frame = -2 Query: 671 NQDLYFKRTVKYVGEPMTHLESIASSAVRAAIKVKASVIICFTSSGRAARLIAKYRPTMP 492 ++D+ +RT + T ++I S A+ + + I+ T SG+ +++AKYRP P Sbjct: 342 HRDILSQRTKE---SQTTITDAIGQSVAHTALNLDVAAIVTPTVSGKTPQMVAKYRPKAP 398 Query: 491 VLSVVIPRLKTNQLKWSFTGAFEARQSLIVRGLFPMLADPRHPAESTSTTNESVLKVALD 312 +++V + +R+ +V G++ A +TT+E +L VA+D Sbjct: 399 IIAVT-------------SNEAVSRRLALVWGVY------TKEAPHVNTTDE-MLDVAVD 438 Query: 311 HGKASGVIKSHDRVVVCQKV-----GDSSVVKIIELDD*AKLAFAQGL 183 SG++K D VV+ V G ++++K+ + D LA QG+ Sbjct: 439 AAVRSGLVKHGDLVVITAGVPVGETGSTNLMKVHVISD--LLAKGQGI 484
>KPYK_DEBHA (Q6BS75) Pyruvate kinase (EC 2.7.1.40) (PK)| Length = 504 Score = 48.1 bits (113), Expect = 2e-05 Identities = 35/139 (25%), Positives = 66/139 (47%), Gaps = 4/139 (2%) Frame = -2 Query: 626 PMTHLESIASSAVRAAIKVKASVIICFTSSGRAARLIAKYRPTMPVLSVVIPRLKTNQLK 447 P E+ A ++V AA + A I+ ++SG +RL++KY+P +PV+ V Sbjct: 379 PTPTTETCAMASVSAAYEQDAKAIVVLSTSGFTSRLVSKYKPNVPVMMVT---------- 428 Query: 446 WSFTGAFEARQSLIVRGLFPMLADPRHPAESTSTTNESVLKVALDHGKASGVIKSHDRVV 267 AR + RG++P + + + ++ E+ L+ A+ G+IK D +V Sbjct: 429 ---RNHRAARYCHLYRGVYPFVYE-KKTVDNWQEDVENRLRWAVSEAIDLGIIKKGDSIV 484 Query: 266 VCQ----KVGDSSVVKIIE 222 Q G S+ V++++ Sbjct: 485 TIQGWTRGSGHSNTVRVVQ 503
>KPYK_CHLMU (Q9PK61) Pyruvate kinase (EC 2.7.1.40) (PK)| Length = 481 Score = 48.1 bits (113), Expect = 2e-05 Identities = 32/119 (26%), Positives = 61/119 (51%), Gaps = 1/119 (0%) Frame = -2 Query: 617 HLESIASSAVRAAIKVKASVIICFTSSGRAARLIAKYRPTMPVLSVVIPRLKTNQLKWSF 438 +LE+I +S ++ A K A II +T +G + ++KYRP +P+++V R +L Sbjct: 358 YLEAIGASGIQIAEKASAKAIIVYTQTGGSPMFLSKYRPYLPIIAVTPNRNVYYRL---- 413 Query: 437 TGAFEARQSLIVRGLFPMLADPRHPAESTSTTNESVLK-VALDHGKASGVIKSHDRVVV 264 + G++PML TS +N +V + A +G G++ ++D+++V Sbjct: 414 ---------AVEWGVYPML---------TSESNRTVWRHQACVYGVEKGILSNYDKILV 454
>KPYK_CHLTR (P94685) Pyruvate kinase (EC 2.7.1.40) (PK)| Length = 485 Score = 44.7 bits (104), Expect = 3e-04 Identities = 31/119 (26%), Positives = 59/119 (49%), Gaps = 1/119 (0%) Frame = -2 Query: 617 HLESIASSAVRAAIKVKASVIICFTSSGRAARLIAKYRPTMPVLSVVIPRLKTNQLKWSF 438 +LE+I S ++ A K A II +T +G + ++KYRP +P+++V R +L Sbjct: 358 YLEAIGFSGIQIAEKASAKAIIVYTQTGGSPMFLSKYRPYLPIIAVTPNRNVYYRL---- 413 Query: 437 TGAFEARQSLIVRGLFPMLADPRHPAESTSTTNESVLK-VALDHGKASGVIKSHDRVVV 264 + G++PML T +N +V + A +G G++ ++D+++V Sbjct: 414 ---------AVEWGVYPML---------TLESNRTVWRHQACVYGVEKGILSNYDKILV 454
>KPYK_AGABI (O94122) Pyruvate kinase (EC 2.7.1.40) (PK)| Length = 532 Score = 44.7 bits (104), Expect = 3e-04 Identities = 34/125 (27%), Positives = 61/125 (48%), Gaps = 2/125 (1%) Frame = -2 Query: 626 PMTHLESIASSAVRAAIKVKASVIICFTSSGRAARLIAKYRPTMPVLSVVIPRLKTNQLK 447 P E++A +AV AA + A ++ ++SG ARL++KYRP +P+++V + Q Sbjct: 389 PTETAETVAIAAVAAAAEQDAKALLVLSTSGETARLVSKYRPKIPIITVT----RNEQ-- 442 Query: 446 WSFTGAFEARQSLIVRGLFPM-LADPRHPAESTSTTN-ESVLKVALDHGKASGVIKSHDR 273 ARQ + RG +P +PR T+ ++ ++ L + A VI+ Sbjct: 443 -------TARQIHLHRGCYPFWYPEPRGVQNHQWQTDVDNRIRFGLRNALALNVIQPGAS 495 Query: 272 VVVCQ 258 ++ Q Sbjct: 496 IIAVQ 500
>KPYK_BACPY (P51182) Pyruvate kinase (EC 2.7.1.40) (PK)| Length = 586 Score = 43.9 bits (102), Expect = 5e-04 Identities = 36/145 (24%), Positives = 65/145 (44%), Gaps = 2/145 (1%) Frame = -2 Query: 611 ESIASSAVRAAIKVKASVIICFTSSGRAARLIAKYRPTMPVLSVVIPRLKTNQLKWSFTG 432 E+I +A AI +K ++ T SG A++IAKYRP PV++V + + +L Sbjct: 358 EAIGQAAAYTAINLKVKAVLAPTESGHTAKMIAKYRPGCPVIAVTSSEMCSRKLS----- 412 Query: 431 AFEARQSLIVRGLFPMLADPRHPAES--TSTTNESVLKVALDHGKASGVIKSHDRVVVCQ 258 ++ G++P++ + + ESV + HG + V Sbjct: 413 --------LIWGVYPIVGKKASSIDEILQESVEESVKHQYVGHGDVVIITAG----VPVG 460 Query: 257 KVGDSSVVKIIELDD*AKLAFAQGL 183 + G ++++KI + D LA QG+ Sbjct: 461 EAGTTNLMKIHVIGD--LLARGQGI 483
>KPYK_LACLA (Q07637) Pyruvate kinase (EC 2.7.1.40) (PK)| Length = 502 Score = 43.9 bits (102), Expect = 5e-04 Identities = 36/119 (30%), Positives = 57/119 (47%) Frame = -2 Query: 620 THLESIASSAVRAAIKVKASVIICFTSSGRAARLIAKYRPTMPVLSVVIPRLKTNQLKWS 441 T E +A+S AA + +I+ T SG ARLI+K+RP +L++ + Sbjct: 384 TVTEVVAASVKNAAEAMDIKLIVALTESGNTARLISKHRPNADILAI------------T 431 Query: 440 FTGAFEARQSLIVRGLFPMLADPRHPAESTSTTNESVLKVALDHGKASGVIKSHDRVVV 264 F E R +I G+ P + + ST E KVAL ASG+++S D +++ Sbjct: 432 FDEKVE-RGLMINWGVIPTMTE---KPSSTDDMFEVAEKVAL----ASGLVESGDNIII 482
>KPYK_CLOAB (O08309) Pyruvate kinase (EC 2.7.1.40) (PK)| Length = 473 Score = 42.4 bits (98), Expect = 0.001 Identities = 36/131 (27%), Positives = 64/131 (48%), Gaps = 5/131 (3%) Frame = -2 Query: 605 IASSAVRAAIKVKASVIICFTSSGRAARLIAKYRPTMPVLSVVIPRLKTNQLKWSFTGAF 426 I+ AA ++AS II T +G AR ++KYRP PV++V P K Sbjct: 359 ISLGTCTAAADLEASAIITATQTGSTARTVSKYRPKAPVIAVT-PSEKV----------- 406 Query: 425 EARQSLIVRGLFPMLADPRHPAESTSTTNESVLKVALDHGKASGVIKSHDRVVVCQKV-- 252 AR+ + G+ P+++D +T+E ++ ++D +G ++ D VVV V Sbjct: 407 -ARKLAMSWGVHPIISD------KFGSTDE-LISTSVDKALEAGYVQKGDLVVVAAGVPT 458 Query: 251 ---GDSSVVKI 228 G ++++K+ Sbjct: 459 NVSGTTNMLKV 469
>KPYK_CHLPN (Q9Z984) Pyruvate kinase (EC 2.7.1.40) (PK)| Length = 484 Score = 40.0 bits (92), Expect = 0.007 Identities = 31/127 (24%), Positives = 60/127 (47%), Gaps = 6/127 (4%) Frame = -2 Query: 617 HLESIASSAVRAAIKVKASVIICFTSSGRAARLIAKYRPTMPVLSV-----VIPRLKTNQ 453 +L +I + ++ A + A +I +T SG + ++KYRP P+++V V RL Sbjct: 358 YLSAIGLAGIQIAERADAKALIVYTESGSSPMFLSKYRPKFPIIAVTPSTSVYYRL---A 414 Query: 452 LKWSFTGAFEARQSLIVRGLFPMLADPRHPAESTSTTNESVLK-VALDHGKASGVIKSHD 276 L+W G++PML T ++ +V + A +G G++ ++D Sbjct: 415 LEW---------------GVYPML---------TQESDRAVWRHQACIYGIEQGILSNYD 450 Query: 275 RVVVCQK 255 R++V + Sbjct: 451 RILVLSR 457
>KPYK2_AGRVI (Q44473) Pyruvate kinase (EC 2.7.1.40) (PK)| Length = 482 Score = 37.7 bits (86), Expect = 0.032 Identities = 14/43 (32%), Positives = 30/43 (69%) Frame = -2 Query: 608 SIASSAVRAAIKVKASVIICFTSSGRAARLIAKYRPTMPVLSV 480 ++A++A A+ + + V++ +TSSG A I++ RP +P+L++ Sbjct: 359 AVATAAANVAVALGSPVVVAYTSSGTTAARISRARPALPILAL 401
>KPYK_CLOPE (Q46289) Pyruvate kinase (EC 2.7.1.40) (PK)| Length = 474 Score = 37.4 bits (85), Expect = 0.042 Identities = 14/49 (28%), Positives = 30/49 (61%) Frame = -2 Query: 626 PMTHLESIASSAVRAAIKVKASVIICFTSSGRAARLIAKYRPTMPVLSV 480 P ++I+ SA + A K I+ T +G A++++KY+P+ P++++ Sbjct: 354 PDAFADAISYSASKTASKFPTKAIVAATQTGSTAKILSKYKPSCPIIAI 402
>KPYK2_SYNY3 (P73534) Pyruvate kinase 2 (EC 2.7.1.40) (PK 2)| Length = 591 Score = 37.0 bits (84), Expect = 0.055 Identities = 28/100 (28%), Positives = 51/100 (51%) Frame = -2 Query: 608 SIASSAVRAAIKVKASVIICFTSSGRAARLIAKYRPTMPVLSVVIPRLKTNQLKWSFTGA 429 +I+S+ + A + A+ I+ T +G AR ++K+RP P+L+V P + Sbjct: 362 AISSAVSQIAETLNAAAIMSLTKTGSTARHVSKFRPKTPILAVT-PHVDV---------- 410 Query: 428 FEARQSLIVRGLFPMLADPRHPAESTSTTNESVLKVALDH 309 +RQ +V G+ P+L STS T ++ + VA ++ Sbjct: 411 --SRQLQLVWGVKPLLV---LDLPSTSQTFQAAINVAQEN 445
>LAMA1_HUMAN (P25391) Laminin alpha-1 chain precursor (Laminin A chain)| Length = 3075 Score = 33.1 bits (74), Expect = 0.80 Identities = 20/67 (29%), Positives = 25/67 (37%) Frame = +3 Query: 393 EASNYE*LSCFKCACEAPLQLICF*TRNDNRQDRHGGPVLGN*PCSSSR*GEANDDRSLN 572 + S YE C C C+ L ++D D H G G PC GE D L Sbjct: 385 KVSPYEDEPCRPCNCDPVGSLSSVCIKDDLHSDLHNGKQPGQCPCKEGYTGEKCDRCQLG 444 Query: 573 FDSRPHC 593 + P C Sbjct: 445 YKDYPTC 451
>FTHS_LACJO (Q74JC1) Formate--tetrahydrofolate ligase (EC 6.3.4.3)| (Formyltetrahydrofolate synthetase) (FHS) (FTHFS) Length = 557 Score = 30.8 bits (68), Expect = 4.0 Identities = 14/39 (35%), Positives = 24/39 (61%) Frame = +1 Query: 541 EVKQMMTEALTLIAARTAEEAIDSKWVMGSPTYFTVRLK 657 E+K+M + L +I A+T D K ++G+P FT+ +K Sbjct: 474 EIKKMGKDNLPVIMAKTQYSFTDKKSILGAPKDFTLHVK 512
>ORYB_ORYSA (P25777) Oryzain beta chain precursor (EC 3.4.22.-)| Length = 471 Score = 30.8 bits (68), Expect = 4.0 Identities = 26/78 (33%), Positives = 34/78 (43%), Gaps = 13/78 (16%) Frame = -1 Query: 600 FLCSAGGYQS*GFGHHLLHLIWTSCK---ANCQVQAHHAC-----PVC-----CHSSSKN 460 F C AG FG L L+W C A C + H +C PVC S+SKN Sbjct: 389 FSCPAGSTCCCAFGFRNLCLVWGCCPVEGATC-CKDHASCCPPDYPVCNTRAGTCSASKN 447 Query: 459 KSIEVELHRRI*SKTITH 406 + V+ +R +K TH Sbjct: 448 SPLSVKALKRTLAKLNTH 465
>KPYK2_ECOLI (P21599) Pyruvate kinase II (EC 2.7.1.40) (PK-2)| Length = 479 Score = 29.6 bits (65), Expect = 8.8 Identities = 31/138 (22%), Positives = 63/138 (45%), Gaps = 6/138 (4%) Frame = -2 Query: 611 ESIASSAVRAAIKVKA-SVIICFTSSGRAARLIAKYRPTMPVLSVVIPRLKTNQLKWSFT 435 E+IA SA+ AA +K + II T SGR A + ++ +P+ + + ++ + T Sbjct: 362 EAIAMSAMYAANHLKGVTAIITMTESGRTALMTSRISSGLPIFA-----MSRHERTLNLT 416 Query: 434 GAFEARQSLIVRGLFPMLADPRHPAESTSTTNESVLKVALDHGKASGVIKSHDRVVVCQ- 258 + RG+ P+ D + + ++ ++L + G + S D V+V Q Sbjct: 417 ALY--------RGVTPVHFDSANDGVAAASEAVNLL-------RDKGYLMSGDLVIVTQG 461 Query: 257 ----KVGDSSVVKIIELD 216 VG ++ +I+ ++ Sbjct: 462 DVMSTVGSTNTTRILTVE 479
>CRCB_XANAC (Q8PKZ5) Protein crcB homolog| Length = 133 Score = 29.6 bits (65), Expect = 8.8 Identities = 28/82 (34%), Positives = 38/82 (46%), Gaps = 4/82 (4%) Frame = +1 Query: 298 DALPWSRATFNT-DSFV--VLVDSAG*RGSASMGKRPLTMSDCLASNAPVK-LHFN*FVF 465 + PW T N SFV VL+ RG +S R L + + L VF Sbjct: 37 NVFPWGTLTVNLLGSFVAGVLLVWLDARGPSSWPLRALLIVGVIGGLTTFSSLMMECLVF 96 Query: 466 RRGMTTDRTGMVGLYLAISLAA 531 R TDR+ M+G+YLA++L A Sbjct: 97 AR---TDRSTMIGIYLAVTLLA 115
>RELB_XENLA (P51510) Transcription factor RelB homolog| Length = 497 Score = 29.6 bits (65), Expect = 8.8 Identities = 14/58 (24%), Positives = 31/58 (53%) Frame = -2 Query: 389 PMLADPRHPAESTSTTNESVLKVALDHGKASGVIKSHDRVVVCQKVGDSSVVKIIELD 216 P+L+DP + +ST+T+ + ++ ++G+ G + ++C KV ++ I D Sbjct: 239 PVLSDPIYDKKSTNTSELKISRMNKEYGRCEG---GEEVYILCDKVQKEDILVIFGED 293 Database: uniprot_sprot.fasta Posted date: May 25, 2006 5:36 PM Number of letters in database: 80,573,946 Number of sequences in database: 219,361 Lambda K H 0.318 0.135 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 97,855,696 Number of Sequences: 219361 Number of extensions: 2002170 Number of successful extensions: 4971 Number of sequences better than 10.0: 56 Number of HSP's better than 10.0 without gapping: 4790 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 4953 length of database: 80,573,946 effective HSP length: 108 effective length of database: 56,882,958 effective search space used: 6655306086 frameshift window, decay const: 50, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)