ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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| Clone Name | rbasd16l20 |
|---|---|
| Clone Library Name | barley_pub |
>BAK1_ARATH (Q94F62) BRASSINOSTEROID INSENSITIVE 1-associated receptor kinase 1| precursor (EC 2.7.11.1) (BRI1-associated receptor kinase 1) (Somatic embryogenesis receptor-like kinase 3) Length = 615 Score = 66.2 bits (160), Expect = 8e-11 Identities = 45/121 (37%), Positives = 65/121 (53%), Gaps = 6/121 (4%) Frame = -3 Query: 613 ALRGTIGYIAPEMISRSFGVISSKSDVYSFGMLLLEMAGGRRNAD-PNAANTSKAYYPSW 437 A+RGTIG+IAPE +S G S K+DV+ +G++LLE+ G+R D AN W Sbjct: 451 AVRGTIGHIAPEYLST--GKSSEKTDVFGYGVMLLELITGQRAFDLARLANDDDVMLLDW 508 Query: 436 VYDRLIQQDHVGEISTHVDVEMH-----ELERKLCIVGLWCIQMKSNDRPTMSDTIEMLE 272 V L ++ ++ VDV++ E +L V L C Q +RP MS+ + MLE Sbjct: 509 VKGLLKEK----KLEALVDVDLQGNYKDEEVEQLIQVALLCTQSSPMERPKMSEVVRMLE 564 Query: 271 G 269 G Sbjct: 565 G 565
>SRK6_BRAOE (Q09092) Putative serine/threonine-protein kinase receptor precursor| (EC 2.7.11.1) (S-receptor kinase) (SRK) Length = 849 Score = 66.2 bits (160), Expect = 8e-11 Identities = 41/150 (27%), Positives = 74/150 (49%), Gaps = 7/150 (4%) Frame = -3 Query: 655 AKLYPRDTSFVPSRALRGTIGYIAPEMISRSFGVISSKSDVYSFGMLLLEMAGGRRNA-- 482 A+++ RD + + + GT GY++PE +G+ S KSDV+SFG+++LE+ G++N Sbjct: 675 ARIFERDETEANTMKVVGTYGYMSPEYAM--YGIFSEKSDVFSFGVIVLEIVSGKKNRGF 732 Query: 481 -DPNAANTSKAY-YPSWVYDR---LIQQDHVGEISTHVDVEMHELERKLCIVGLWCIQMK 317 + + N +Y + W R ++ V +S+ + + K +GL C+Q Sbjct: 733 YNLDYENDLLSYVWSRWKEGRALEIVDPVIVDSLSSQPSIFQPQEVLKCIQIGLLCVQEL 792 Query: 316 SNDRPTMSDTIEMLEGSVDALQMPSRPFFC 227 + RP MS + M + P P +C Sbjct: 793 AEHRPAMSSVVWMFGSEATEIPQPKPPGYC 822
>NAK_ARATH (P43293) Probable serine/threonine-protein kinase NAK (EC 2.7.11.1)| Length = 389 Score = 62.4 bits (150), Expect = 1e-09 Identities = 42/124 (33%), Positives = 65/124 (52%), Gaps = 2/124 (1%) Frame = -3 Query: 637 DTSFVPSRALRGTIGYIAPEMISRSFGVISSKSDVYSFGMLLLEMAGGRRNADPNAANTS 458 D S V +R + GT GY APE ++ G +S KSDVYSFG++LLE+ GRR D N Sbjct: 232 DNSHVSTRVM-GTQGYAAPEYLAT--GHLSVKSDVYSFGVVLLELLSGRRAIDKNQP-VG 287 Query: 457 KAYYPSWVYDRLIQQDHVGEISTHVDVEMHELER--KLCIVGLWCIQMKSNDRPTMSDTI 284 + W L + + + + L R K+ ++ L CI + + RPTM++ + Sbjct: 288 EHNLVDWARPYLTNKRRLLRVMDPRLQGQYSLTRALKIAVLALDCISIDAKSRPTMNEIV 347 Query: 283 EMLE 272 + +E Sbjct: 348 KTME 351
>APK1A_ARATH (Q06548) Protein kinase APK1A, chloroplast precursor (EC 2.7.11.1)| Length = 410 Score = 62.0 bits (149), Expect = 2e-09 Identities = 40/124 (32%), Positives = 66/124 (53%), Gaps = 2/124 (1%) Frame = -3 Query: 637 DTSFVPSRALRGTIGYIAPEMISRSFGVISSKSDVYSFGMLLLEMAGGRRNADPNAANTS 458 D S V +R + GT GY APE ++ G +++KSDVYSFG++LLE+ GRR D N + Sbjct: 232 DKSHVSTRVM-GTHGYAAPEYLAT--GHLTTKSDVYSFGVVLLELLSGRRAVDKNRPSGE 288 Query: 457 KAYYPSWVYDRLIQQDHVGEISTHVDVEMHELER--KLCIVGLWCIQMKSNDRPTMSDTI 284 + W L+ + + + + + + +E K+ + L C+ + RP MS+ + Sbjct: 289 RNLV-EWAKPYLVNKRKIFRVIDNRLQDQYSMEEACKVATLSLRCLTTEIKLRPNMSEVV 347 Query: 283 EMLE 272 LE Sbjct: 348 SHLE 351
>RPK1_IPONI (P93194) Receptor-like protein kinase precursor (EC 2.7.11.1)| Length = 1109 Score = 60.1 bits (144), Expect = 6e-09 Identities = 40/134 (29%), Positives = 68/134 (50%), Gaps = 7/134 (5%) Frame = -3 Query: 655 AKLYPRDTSFVPSRALRGTIGYIAPEMISRSFGVISSK-SDVYSFGMLLLEMAGGRRNAD 479 AKL + + +PS ++GTIGY+APE +F + S+ SDVYS+G++LLE+ ++ D Sbjct: 964 AKLLDQSATSIPSNTVQGTIGYMAPE---NAFTTVKSRESDVYSYGVVLLELITRKKALD 1020 Query: 478 PNAANTSKAYYPSWVYDRLIQQDHVGEI------STHVDVEMHELERKLCIVGLWCIQMK 317 P+ + WV Q + +I +D + E + + L C + + Sbjct: 1021 PSF--NGETDIVGWVRSVWTQTGEIQKIVDPSLLDELIDSSVMEQVTEALSLALRCAEKE 1078 Query: 316 SNDRPTMSDTIEML 275 + RPTM D ++ L Sbjct: 1079 VDKRPTMRDVVKQL 1092
>APK1B_ARATH (P46573) Protein kinase APK1B, chloroplast precursor (EC 2.7.11.1)| Length = 412 Score = 56.6 bits (135), Expect = 6e-08 Identities = 38/124 (30%), Positives = 64/124 (51%), Gaps = 2/124 (1%) Frame = -3 Query: 637 DTSFVPSRALRGTIGYIAPEMISRSFGVISSKSDVYSFGMLLLEMAGGRRNADPNAANTS 458 D S V +R + GT GY APE ++ G +++KSDVYS+G++LLE+ GRR D N Sbjct: 233 DKSHVSTRIM-GTYGYAAPEYLAT--GHLTTKSDVYSYGVVLLEVLSGRRAVDKNRP-PG 288 Query: 457 KAYYPSWVYDRLIQQDHVGEISTHVDVEMHELER--KLCIVGLWCIQMKSNDRPTMSDTI 284 + W L + + + + + + +E K+ + L C+ + RP M++ + Sbjct: 289 EQKLVEWARPLLANKRKLFRVIDNRLQDQYSMEEACKVATLALRCLTFEIKLRPNMNEVV 348 Query: 283 EMLE 272 LE Sbjct: 349 SHLE 352
>CRI4_MAIZE (O24585) Putative receptor protein kinase CRINKLY4 precursor (EC| 2.7.11.1) Length = 901 Score = 56.2 bits (134), Expect = 8e-08 Identities = 42/134 (31%), Positives = 65/134 (48%), Gaps = 2/134 (1%) Frame = -3 Query: 649 LYPRDTSFVPSRALRGTIGYIAPEMISRSFGVISSKSDVYSFGMLLLEMAGGRRNADPNA 470 L P D+ S GT+GY+ PE + +++KSDVYSFG++LLE+ GR+ D Sbjct: 658 LGPADSGTPLSELPAGTLGYLDPEYYRLHY--LTTKSDVYSFGVVLLEILSGRKAID--- 712 Query: 469 ANTSKAYYPSWVYDRLIQQDHVGEISTHVDVEMHELE--RKLCIVGLWCIQMKSNDRPTM 296 + W LI+ + I V +LE +K+ V C++M+ DRP+M Sbjct: 713 MQFEEGNIVEWAVP-LIKAGDIFAILDPVLSPPSDLEALKKIASVACKCVRMRGKDRPSM 771 Query: 295 SDTIEMLEGSVDAL 254 LE ++ L Sbjct: 772 DKVTTALEHALALL 785
>RLK5_ARATH (P47735) Receptor-like protein kinase 5 precursor (EC 2.7.11.1)| Length = 999 Score = 54.7 bits (130), Expect = 2e-07 Identities = 35/113 (30%), Positives = 57/113 (50%) Frame = -3 Query: 610 LRGTIGYIAPEMISRSFGVISSKSDVYSFGMLLLEMAGGRRNADPNAANTSKAYYPSWVY 431 + G+ GYIAPE + ++ KSD+YSFG++LLE+ G++ D + A WV Sbjct: 858 IAGSCGYIAPEYVYTLR--VNEKSDIYSFGVVLLELVTGKQPTDSELGDKDMA---KWVC 912 Query: 430 DRLIQQDHVGEISTHVDVEMHELERKLCIVGLWCIQMKSNDRPTMSDTIEMLE 272 L + I +D++ E K+ +GL C +RP+M + ML+ Sbjct: 913 TALDKCGLEPVIDPKLDLKFKEEISKVIHIGLLCTSPLPLNRPSMRKVVIMLQ 965
>KPEL_DROME (Q05652) Probable serine/threonine-protein kinase pelle (EC| 2.7.11.1) Length = 501 Score = 52.4 bits (124), Expect = 1e-06 Identities = 37/114 (32%), Positives = 61/114 (53%), Gaps = 3/114 (2%) Frame = -3 Query: 604 GTIGYIAPEMISRSFGVISSKSDVYSFGMLLLEMAGGRRNADPNAANTSKAYYPSWVYDR 425 GT Y+ PE R+F +S+ DVYSFG++LLE+ GR+ D N +K +V + Sbjct: 386 GTKIYLPPEF--RNFRQLSTGVDVYSFGIVLLEVFTGRQVTDRVPENETKKNLLDYVKQQ 443 Query: 424 LIQQDHVGEISTHVDVEM-HELERKLCIV--GLWCIQMKSNDRPTMSDTIEMLE 272 +Q+ + + H+ M EL+ +C + GL C + DRP+M+ ++ E Sbjct: 444 W-RQNRMELLEKHLAAPMGKELDMCMCAIEAGLHCTALDPQDRPSMNAVLKRFE 496
>EXS_ARATH (Q9LYN8) Leucine-rich repeat receptor protein kinase EXS precursor| (EC 2.7.11.1) (Extra sporogenous cells protein) (EXCESS MICROSPOROCYTES1 protein) Length = 1192 Score = 52.4 bits (124), Expect = 1e-06 Identities = 33/117 (28%), Positives = 54/117 (46%), Gaps = 1/117 (0%) Frame = -3 Query: 619 SRALRGTIGYIAPEMISRSFGVISSKSDVYSFGMLLLEMAGGRRNADPNAANTSKAYYPS 440 S + GT GYI PE + ++K DVYSFG++LLE+ G+ P+ + Sbjct: 1076 STVIAGTFGYIPPEYGQSARA--TTKGDVYSFGVILLELVTGKEPTGPDFKESEGGNLVG 1133 Query: 439 WVYDRLIQQDHVGEIS-THVDVEMHELERKLCIVGLWCIQMKSNDRPTMSDTIEMLE 272 W ++ Q V I V V + + +L + + C+ RP M D ++ L+ Sbjct: 1134 WAIQKINQGKAVDVIDPLLVSVALKNSQLRLLQIAMLCLAETPAKRPNMLDVLKALK 1190
>TMK1_ARATH (P43298) Putative receptor protein kinase TMK1 precursor (EC| 2.7.11.1) Length = 942 Score = 50.8 bits (120), Expect = 3e-06 Identities = 38/135 (28%), Positives = 64/135 (47%), Gaps = 4/135 (2%) Frame = -3 Query: 652 KLYPRDTSFVPSRALRGTIGYIAPEMISRSFGVISSKSDVYSFGMLLLEMAGGRRNADPN 473 +L P + +R + GT GY+APE G +++K DVYSFG++L+E+ GR++ D + Sbjct: 740 RLAPEGKGSIETR-IAGTFGYLAPEYAVT--GRVTTKVDVYSFGVILMELITGRKSLDES 796 Query: 472 AANTSKAYYPSWVYDRLIQQD--HVGEISTHVDVEMHELERKLCIVGL--WCIQMKSNDR 305 S + SW I ++ I T +D++ L + L C + R Sbjct: 797 QPEES-IHLVSWFKRMYINKEASFKKAIDTTIDLDEETLASVHTVAELAGHCCAREPYQR 855 Query: 304 PTMSDTIEMLEGSVD 260 P M + +L V+ Sbjct: 856 PDMGHAVNILSSLVE 870
>CX32_ARATH (P27450) Probable serine/threonine-protein kinase Cx32, chloroplast| precursor (EC 2.7.11.1) Length = 419 Score = 50.8 bits (120), Expect = 3e-06 Identities = 43/148 (29%), Positives = 66/148 (44%), Gaps = 9/148 (6%) Frame = -3 Query: 655 AKLYPRDTSFVPSRALRGTIGYIAPEMISRSFGVISSKSDVYSFGMLLLEMAGGRRNADP 476 AKL P D + + GT GY APE ++ G + KSDV++FG++LLE+ G A Sbjct: 240 AKLGPADEKSHVTTRIMGTYGYAAPEYMAT--GHLYVKSDVFAFGVVLLEIMTG-LTAHN 296 Query: 475 NAANTSKAYYPSWVYDRLIQQDHV---------GEISTHVDVEMHELERKLCIVGLWCIQ 323 + W+ L + V G+ +T V EM + L CI+ Sbjct: 297 TKRPRGQESLVDWLRPELSNKHRVKQIMDKGIKGQYTTKVATEMAR-------ITLSCIE 349 Query: 322 MKSNDRPTMSDTIEMLEGSVDALQMPSR 239 +RP M + +E+LE +P+R Sbjct: 350 PDPKNRPHMKEVVEVLEHIQGLNVVPNR 377
>NORK_PEA (Q8LKZ1) Nodulation receptor kinase precursor (EC 2.7.11.1)| Length = 924 Score = 50.1 bits (118), Expect = 6e-06 Identities = 39/138 (28%), Positives = 62/138 (44%), Gaps = 7/138 (5%) Frame = -3 Query: 655 AKLYPRDTSFVPSRALRGTIGYIAPEMISRSFGVISSKSDVYSFGMLLLEMAGGRR---- 488 +K P++ S +RGT GY+ PE +S KSDV+SFG++LLE+ GR Sbjct: 743 SKYAPQEGDSYVSLEVRGTAGYLDPEYYKTQ--QLSEKSDVFSFGVVLLEIVSGREPLNI 800 Query: 487 ---NADPNAANTSKAYYPSWVYDRLIQQDHVGEISTHVDVEMHELERKLCIVGLWCIQMK 317 + + +K Y + D ++ G H + +E V L C++ Sbjct: 801 KRPRVEWSLVEWAKPYIRASKVDEIVDPGIKG--GYHAEALWRVVE-----VALQCLEPY 853 Query: 316 SNDRPTMSDTIEMLEGSV 263 S RP M D + LE ++ Sbjct: 854 STYRPCMVDIVRELEDAL 871
>NORK_MEDTR (Q8L4H4) Nodulation receptor kinase precursor (EC 2.7.11.1) (Does not| make infections protein 2) (Symbiosis receptor-like kinase) (MtSYMRK) Length = 925 Score = 49.7 bits (117), Expect = 8e-06 Identities = 39/138 (28%), Positives = 62/138 (44%), Gaps = 7/138 (5%) Frame = -3 Query: 655 AKLYPRDTSFVPSRALRGTIGYIAPEMISRSFGVISSKSDVYSFGMLLLEMAGGRR---- 488 +K P++ S +RGT GY+ PE +S KSDV+SFG++LLE+ GR Sbjct: 744 SKYAPQEGDSYVSLEVRGTAGYLDPEYYKTQ--QLSEKSDVFSFGVVLLEIVSGREPLNI 801 Query: 487 ---NADPNAANTSKAYYPSWVYDRLIQQDHVGEISTHVDVEMHELERKLCIVGLWCIQMK 317 + + +K Y + D ++ G H + +E V L C++ Sbjct: 802 KRPRIEWSLVEWAKPYIRASKVDEIVDPGIKG--GYHAEALWRVVE-----VALQCLEPY 854 Query: 316 SNDRPTMSDTIEMLEGSV 263 S RP M D + LE ++ Sbjct: 855 STYRPCMVDIVRELEDAL 872
>KPRO_MAIZE (P17801) Putative receptor protein kinase ZmPK1 precursor (EC| 2.7.11.1) Length = 817 Score = 49.3 bits (116), Expect = 1e-05 Identities = 40/140 (28%), Positives = 67/140 (47%), Gaps = 9/140 (6%) Frame = -3 Query: 652 KLYPRDTSFVPSRALRGTIGYIAPEMISRSFGVISSKSDVYSFGMLLLEMAGGRRNADPN 473 KL R S +RGT+GYIAPE +S I++K DVYS+G++LLE+ G R ++ Sbjct: 681 KLLNRGGSTQNVSHVRGTLGYIAPEWVSSL--PITAKVDVYSYGVVLLELLTGTRVSE-L 737 Query: 472 AANTSKAYYPSWVYDRLIQQDHVGEISTHVDVEM---------HELERKLCIVGLWCIQM 320 T + + R++ GE + +D + + R L + + C++ Sbjct: 738 VGGTDEVHSMLRKLVRMLSAKLEGEEQSWIDGYLDSKLNRPVNYVQARTLIKLAVSCLEE 797 Query: 319 KSNDRPTMSDTIEMLEGSVD 260 + RPTM ++ L + D Sbjct: 798 DRSKRPTMEHAVQTLLSADD 817
>PBS1_ARATH (Q9FE20) Serine/threonine-protein kinase PBS1 (EC 2.7.11.1)| (AvrPphB susceptible protein 1) Length = 456 Score = 48.5 bits (114), Expect = 2e-05 Identities = 47/148 (31%), Positives = 67/148 (45%), Gaps = 9/148 (6%) Frame = -3 Query: 655 AKLYPR-DTSFVPSRALRGTIGYIAPEMISRSFGVISSKSDVYSFGMLLLEMAGGRRNAD 479 AKL P D S V +R + GT GY APE G ++ KSDVYSFG++ LE+ GR+ D Sbjct: 235 AKLGPTGDKSHVSTRVM-GTYGYCAPEYAMT--GQLTVKSDVYSFGVVFLELITGRKAID 291 Query: 478 ---PNAANTSKAYYPSWVYDR-----LIQQDHVGEISTHVDVEMHELERKLCIVGLWCIQ 323 P+ A+ DR L G T L + L + + CIQ Sbjct: 292 SEMPHGEQNLVAWARPLFNDRRKFIKLADPRLKGRFPTRA------LYQALAVASM-CIQ 344 Query: 322 MKSNDRPTMSDTIEMLEGSVDALQMPSR 239 ++ RP ++D + L + PS+ Sbjct: 345 EQAATRPLIADVVTALSYLANQAYDPSK 372
>PSKR_DAUCA (Q8LPB4) Phytosulfokine receptor precursor (EC 2.7.11.1)| (Phytosulfokine LRR receptor kinase) Length = 1021 Score = 48.1 bits (113), Expect = 2e-05 Identities = 42/128 (32%), Positives = 58/128 (45%), Gaps = 2/128 (1%) Frame = -3 Query: 649 LYPRDTSFVPSRALRGTIGYIAPEMISRSFGVISSKSDVYSFGMLLLEMAGGRRNADPNA 470 + P DT L GT+GYI PE S V + K DVYSFG++LLE+ GRR D Sbjct: 894 ILPYDTHVTTD--LVGTLGYIPPEYGQAS--VATYKGDVYSFGVVLLELLTGRRPMDVCK 949 Query: 469 ANTSKAYYPSWVYDRLIQQDHVGEISTHVDVEMHELERKLCIVGLWCIQMKSN--DRPTM 296 S+ SWV ++ + EI + E L ++ + C + N RPT Sbjct: 950 PRGSRDLI-SWVL-QMKTEKRESEIFDPFIYDKDHAEEMLLVLEIACRCLGENPKTRPTT 1007 Query: 295 SDTIEMLE 272 + LE Sbjct: 1008 QQLVSWLE 1015
>CLV1_ARATH (Q9SYQ8) Receptor protein kinase CLAVATA1 precursor (EC 2.7.11.1)| Length = 980 Score = 45.8 bits (107), Expect = 1e-04 Identities = 30/117 (25%), Positives = 52/117 (44%), Gaps = 4/117 (3%) Frame = -3 Query: 613 ALRGTIGYIAPEMISRSFGVISSKSDVYSFGMLLLEMAGGRRNADPNAANTSKAYYPSWV 434 ++ G+ GYIAPE + KSDVYSFG++LLE+ G++ + Sbjct: 853 SIAGSYGYIAPEYAYTL--KVDEKSDVYSFGVVLLELIAGKKPVGEFGEGVDIVRWVRNT 910 Query: 433 YDRLIQQDHVGEISTHVDVEMHELERKLCI----VGLWCIQMKSNDRPTMSDTIEML 275 + + Q + VD + I + + C++ ++ RPTM + + ML Sbjct: 911 EEEITQPSDAAIVVAIVDPRLTGYPLTSVIHVFKIAMMCVEEEAAARPTMREVVHML 967
>RLCK7_ARATH (Q9LQQ8) Probable serine/threonine-protein kinase RLCKVII (EC| 2.7.11.1) Length = 423 Score = 45.4 bits (106), Expect = 1e-04 Identities = 38/143 (26%), Positives = 62/143 (43%), Gaps = 3/143 (2%) Frame = -3 Query: 655 AKLYPRDTSFVPSRALRGTIGYIAPEMISRSFGVISSKSDVYSFGMLLLEMAGGRRNADP 476 AK+ P S + GT GY AP+ G ++ KSD+YSFG++LLE+ GR+ D Sbjct: 252 AKVGPSGDKTHVSTRVMGTYGYCAPDYAMT--GQLTFKSDIYSFGVVLLELITGRKAID- 308 Query: 475 NAANTSKAYYPSWVYDRLIQQDHVGEISTHV---DVEMHELERKLCIVGLWCIQMKSNDR 305 N W + + ++ + + L + L I + C+Q + R Sbjct: 309 NTKTRKDQNLVGWARPLFKDRRNFPKMVDPLLQGQYPVRGLYQALAISAM-CVQEQPTMR 367 Query: 304 PTMSDTIEMLEGSVDALQMPSRP 236 P +SD + L + P+ P Sbjct: 368 PVVSDVVLALNFLASSKYDPNSP 390
>IRAK4_HUMAN (Q9NWZ3) Interleukin-1 receptor-associated kinase 4 (EC 2.7.11.1)| (IRAK-4) (NY-REN-64 antigen) Length = 460 Score = 45.1 bits (105), Expect = 2e-04 Identities = 33/116 (28%), Positives = 56/116 (48%), Gaps = 5/116 (4%) Frame = -3 Query: 604 GTIGYIAPEMISRSFGVISSKSDVYSFGMLLLEMAGGRRNADPNAANTSKAYYPSWVYDR 425 GT Y+APE + G I+ KSD+YSFG++LLE+ G D + P + D Sbjct: 350 GTTAYMAPEALR---GEITPKSDIYSFGVVLLEIITGLPAVDEHRE-------PQLLLDI 399 Query: 424 LIQ-QDHVGEISTHVDVEMHELE----RKLCIVGLWCIQMKSNDRPTMSDTIEMLE 272 + +D I ++D +M++ + + V C+ K N RP + ++L+ Sbjct: 400 KEEIEDEEKTIEDYIDKKMNDADSTSVEAMYSVASQCLHEKKNKRPDIKKVQQLLQ 455
>SIRK_ARATH (O64483) Senescence-induced receptor-like serine/threonine-protein| kinase precursor (FLG22-induced receptor-like kinase 1) Length = 876 Score = 44.7 bits (104), Expect = 2e-04 Identities = 38/121 (31%), Positives = 57/121 (47%), Gaps = 5/121 (4%) Frame = -3 Query: 619 SRALRGTIGYIAPEMISRSFGVISSKSDVYSFGMLLLEMAGGRRNADPNAANTSKAYYPS 440 S + G+IGY+ PE S ++ KSDVYS G++LLE+ G+ ++ T K + Sbjct: 731 STVVAGSIGYLDPEYYSTR--QMNEKSDVYSLGVVLLEVITGQPAI--ASSKTEKVHISD 786 Query: 439 WVYDRLIQQDHVGEISTHVDVEMHE-----LERKLCIVGLWCIQMKSNDRPTMSDTIEML 275 V L G+I VD + E K+ + L C + S RPTMS + L Sbjct: 787 HVRSILAN----GDIRGIVDQRLRERYDVGSAWKMSEIALACTEHTSAQRPTMSQVVMEL 842 Query: 274 E 272 + Sbjct: 843 K 843
>IRAK4_MOUSE (Q8R4K2) Interleukin-1 receptor-associated kinase 4 (EC 2.7.11.1)| (IRAK-4) Length = 459 Score = 44.7 bits (104), Expect = 2e-04 Identities = 36/133 (27%), Positives = 60/133 (45%), Gaps = 5/133 (3%) Frame = -3 Query: 655 AKLYPRDTSFVPSRALRGTIGYIAPEMISRSFGVISSKSDVYSFGMLLLEMAGGRRNADP 476 A+ R V + + GT Y+APE + G I+ KSD+YSFG++LLE+ G D Sbjct: 333 ARASARLAQTVMTSRIVGTTAYMAPEALR---GEITPKSDIYSFGVVLLELITGLAAVDE 389 Query: 475 NAANTSKAYYPSWVYDRLIQ-QDHVGEISTHVDVEMHELE----RKLCIVGLWCIQMKSN 311 N P + D + +D I + D +M + + + C+ K N Sbjct: 390 NRE-------PQLLLDIKEEIEDEEKTIEDYTDEKMSDADPASVEAMYSAASQCLHEKKN 442 Query: 310 DRPTMSDTIEMLE 272 RP ++ ++L+ Sbjct: 443 RRPDIAKVQQLLQ 455
>BRL3_ARATH (Q9LJF3) Serine/threonine-protein kinase BRI1-like 3 precursor (EC| 2.7.11.1) (BRASSINOSTEROID INSENSITIVE 1-like protein 3) Length = 1164 Score = 44.3 bits (103), Expect = 3e-04 Identities = 35/120 (29%), Positives = 59/120 (49%), Gaps = 7/120 (5%) Frame = -3 Query: 610 LRGTIGYIAPEMISRSFGVISSKSDVYSFGMLLLEMAGGRRNADP-------NAANTSKA 452 L GT GY+ PE +SF ++K DVYS+G++LLE+ G++ DP N +K Sbjct: 1022 LAGTPGYVPPEYY-QSFRC-TAKGDVYSYGVILLELLSGKKPIDPEEFGEDNNLVGWAKQ 1079 Query: 451 YYPSWVYDRLIQQDHVGEISTHVDVEMHELERKLCIVGLWCIQMKSNDRPTMSDTIEMLE 272 Y ++ + V + S V++ +H L+ + C+ + RPTM + M + Sbjct: 1080 LYREKRGAEILDPELVTDKSGDVEL-LHYLK-----IASQCLDDRPFKRPTMIQVMTMFK 1133
>PSKR_ARATH (Q9ZVR7) Putative phytosulfokine receptor precursor (EC 2.7.11.1)| (Phytosulfokine LRR receptor kinase) Length = 1008 Score = 43.9 bits (102), Expect = 4e-04 Identities = 37/122 (30%), Positives = 53/122 (43%), Gaps = 6/122 (4%) Frame = -3 Query: 619 SRALRGTIGYIAPEMISRSFGVISSKSDVYSFGMLLLEMAGGRRNADPNAANTSKAYYPS 440 S L GT+GYI PE S V + K DVYSFG++LLE+ +R D + S Sbjct: 893 STDLVGTLGYIPPEYGQAS--VATYKGDVYSFGVVLLELLTDKRPVDMCKPKGCRDLI-S 949 Query: 439 WVYDRLIQQDHVGEI------STHVDVEMHELERKLCIVGLWCIQMKSNDRPTMSDTIEM 278 WV ++ + E+ S D EM + C+ C+ RPT + Sbjct: 950 WVV-KMKHESRASEVFDPLIYSKENDKEMFRVLEIACL----CLSENPKQRPTTQQLVSW 1004 Query: 277 LE 272 L+ Sbjct: 1005 LD 1006
>BRL1_ARATH (Q9ZWC8) Serine/threonine-protein kinase BRI1-like 1 precursor (EC| 2.7.11.1) (BRASSINOSTEROID INSENSITIVE 1-like protein 1) Length = 1166 Score = 43.1 bits (100), Expect = 7e-04 Identities = 35/120 (29%), Positives = 58/120 (48%), Gaps = 7/120 (5%) Frame = -3 Query: 610 LRGTIGYIAPEMISRSFGVISSKSDVYSFGMLLLEMAGGRRNADP-------NAANTSKA 452 L GT GY+ PE +SF ++K DVYS+G++LLE+ G++ DP N +K Sbjct: 1024 LAGTPGYVPPEYY-QSFRC-TAKGDVYSYGVILLELLSGKKPIDPGEFGEDNNLVGWAKQ 1081 Query: 451 YYPSWVYDRLIQQDHVGEISTHVDVEMHELERKLCIVGLWCIQMKSNDRPTMSDTIEMLE 272 Y ++ + V + S V++ H L+ + C+ + RPTM + M + Sbjct: 1082 LYREKRGAEILDPELVTDKSGDVEL-FHYLK-----IASQCLDDRPFKRPTMIQLMAMFK 1135
>BRI1_ARATH (O22476) BRASSINOSTEROID INSENSITIVE 1 precursor (EC 2.7.11.1)| (AtBRI1) (Brassinosteroid LRR receptor kinase) Length = 1196 Score = 41.2 bits (95), Expect = 0.003 Identities = 39/121 (32%), Positives = 60/121 (49%), Gaps = 8/121 (6%) Frame = -3 Query: 610 LRGTIGYIAPEMISRSFGVISSKSDVYSFGMLLLEMAGGRRNAD-PNAANTSKAYYPSWV 434 L GT GY+ PE +SF S+K DVYS+G++LLE+ G+R D P+ + + WV Sbjct: 1046 LAGTPGYVPPEYY-QSFRC-STKGDVYSYGVVLLELLTGKRPTDSPDFGDNNLV---GWV 1100 Query: 433 YDRLIQQDHVGEISTHVDVEMHELERKLCI-------VGLWCIQMKSNDRPTMSDTIEML 275 +Q IS D E+ + + L I V + C+ ++ RPTM + M Sbjct: 1101 -----KQHAKLRISDVFDPELMKEDPALEIELLQHLKVAVACLDDRAWRRPTMVQVMAMF 1155 Query: 274 E 272 + Sbjct: 1156 K 1156
>RIPK3_HUMAN (Q9Y572) Receptor-interacting serine/threonine-protein kinase 3 (EC| 2.7.11.1) (RIP-like protein kinase 3) (Receptor-interacting protein 3) (RIP-3) Length = 518 Score = 40.8 bits (94), Expect = 0.004 Identities = 34/125 (27%), Positives = 58/125 (46%), Gaps = 9/125 (7%) Frame = -3 Query: 604 GTIGYIAPEMISRSFGVISSKSDVYSFGMLLLEMAGGRRNADPNAANTSKAYYPSWVYDR 425 GT+GY+APE+ S+ SDVYSFG+L+ + GR P PS VY+ Sbjct: 181 GTLGYLAPELFVNVNRKASTASDVYSFGILMWAVLAGREVELPTE--------PSLVYEA 232 Query: 424 LIQQDHVGEIS--THVDVEMHELERKLCIVGLWCIQMKSNDRPTMSDTI-------EMLE 272 + + + ++ E LE ++ L C + DRP+ + + +M+E Sbjct: 233 VCNRQNRPSLAELPQAGPETPGLEGLKELMQL-CWSSEPKDRPSFQECLPKTDEVFQMVE 291 Query: 271 GSVDA 257 +++A Sbjct: 292 NNMNA 296
>BRI1_LYCPE (Q8L899) Systemin receptor SR160 precursor (EC 2.7.11.1)| (Brassinosteroid LRR receptor kinase) Length = 1207 Score = 40.0 bits (92), Expect = 0.006 Identities = 36/125 (28%), Positives = 61/125 (48%), Gaps = 12/125 (9%) Frame = -3 Query: 610 LRGTIGYIAPEMISRSFGVISSKSDVYSFGMLLLEMAGGRRNADPNAANTSKAYYPSW-- 437 L GT GY+ PE +SF S+K DVYS+G++LLE+ G++ D +A+ W Sbjct: 1051 LAGTPGYVPPEYY-QSFRC-STKGDVYSYGVVLLELLTGKQPTD--SADFGDNNLVGWVK 1106 Query: 436 ---------VYDR-LIQQDHVGEISTHVDVEMHELERKLCIVGLWCIQMKSNDRPTMSDT 287 V+DR L+++D +++E+ + + C C+ + RPTM Sbjct: 1107 LHAKGKITDVFDRELLKED------ASIEIELLQHLKVACA----CLDDRHWKRPTMIQV 1156 Query: 286 IEMLE 272 + M + Sbjct: 1157 MAMFK 1161
>BRI1_LYCES (Q8GUQ5) Brassinosteroid LRR receptor kinase precursor (EC 2.7.11.1)| (tBRI1) (Altered brassinolide sensitivity 1) (Systemin receptor SR160) Length = 1207 Score = 40.0 bits (92), Expect = 0.006 Identities = 36/125 (28%), Positives = 61/125 (48%), Gaps = 12/125 (9%) Frame = -3 Query: 610 LRGTIGYIAPEMISRSFGVISSKSDVYSFGMLLLEMAGGRRNADPNAANTSKAYYPSW-- 437 L GT GY+ PE +SF S+K DVYS+G++LLE+ G++ D +A+ W Sbjct: 1051 LAGTPGYVPPEYY-QSFRC-STKGDVYSYGVVLLELLTGKQPTD--SADFGDNNLVGWVK 1106 Query: 436 ---------VYDR-LIQQDHVGEISTHVDVEMHELERKLCIVGLWCIQMKSNDRPTMSDT 287 V+DR L+++D +++E+ + + C C+ + RPTM Sbjct: 1107 LHAKGKITDVFDRELLKED------ASIEIELLQHLKVACA----CLDDRHWKRPTMIQV 1156 Query: 286 IEMLE 272 + M + Sbjct: 1157 MAMFK 1161
>BCK1_YEAST (Q01389) Serine/threonine-protein kinase BCK1/SLK1/SSP31 (EC| 2.7.11.1) Length = 1478 Score = 39.3 bits (90), Expect = 0.010 Identities = 18/41 (43%), Positives = 29/41 (70%) Frame = -3 Query: 610 LRGTIGYIAPEMISRSFGVISSKSDVYSFGMLLLEMAGGRR 488 +RGT+ ++APEM+ G S+K D++S G ++LEM G+R Sbjct: 1339 MRGTVFWMAPEMVDTKQGY-SAKVDIWSLGCIVLEMFAGKR 1378
>RIPK3_RAT (Q9Z2P5) Receptor-interacting serine/threonine-protein kinase 3 (EC| 2.7.11.1) (RIP-like protein kinase 3) (Receptor-interacting protein 3) (RIP-3) (Homocysteine respondent protein HCYP2) Length = 478 Score = 39.3 bits (90), Expect = 0.010 Identities = 20/43 (46%), Positives = 27/43 (62%) Frame = -3 Query: 619 SRALRGTIGYIAPEMISRSFGVISSKSDVYSFGMLLLEMAGGR 491 SR GT+ Y+APE++ G S SDVYSFG+L+ + GR Sbjct: 179 SRDSGGTLAYLAPELLDND-GKASKASDVYSFGVLVWTVLAGR 220
>LCK_HUMAN (P06239) Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2)| (p56-LCK) (Lymphocyte cell-specific protein-tyrosine kinase) (LSK) (T cell-specific protein-tyrosine kinase) Length = 508 Score = 38.9 bits (89), Expect = 0.014 Identities = 36/134 (26%), Positives = 57/134 (42%) Frame = -3 Query: 637 DTSFVPSRALRGTIGYIAPEMISRSFGVISSKSDVYSFGMLLLEMAGGRRNADPNAANTS 458 D + + I + APE I+ +G + KSDV+SFG+LL E+ R P N Sbjct: 390 DNEYTAREGAKFPIKWTAPEAIN--YGTFTIKSDVWSFGILLTEIVTHGRIPYPGMTNPE 447 Query: 457 KAYYPSWVYDRLIQQDHVGEISTHVDVEMHELERKLCIVGLWCIQMKSNDRPTMSDTIEM 278 Y R+++ D+ E E+++L R C + + DRPT + Sbjct: 448 VIQNLERGY-RMVRPDNCPE-------ELYQLMR-------LCWKERPEDRPTFDYLRSV 492 Query: 277 LEGSVDALQMPSRP 236 LE A + +P Sbjct: 493 LEDFFTATEGQYQP 506
>UFO_MOUSE (Q00993) Tyrosine-protein kinase receptor UFO precursor (EC 2.7.10.1)| (Adhesion-related kinase) Length = 888 Score = 38.9 bits (89), Expect = 0.014 Identities = 37/139 (26%), Positives = 63/139 (45%) Frame = -3 Query: 652 KLYPRDTSFVPSRALRGTIGYIAPEMISRSFGVISSKSDVYSFGMLLLEMAGGRRNADPN 473 K+Y D + R + + +IA E ++ V +SKSDV+SFG+ + E+A + P Sbjct: 690 KIYNGDY-YRQGRIAKMPVKWIAIESLADR--VYTSKSDVWSFGVTMWEIATRGQTPYPG 746 Query: 472 AANTSKAYYPSWVYDRLIQQDHVGEISTHVDVEMHELERKLCIVGLWCIQMKSNDRPTMS 293 N S +YD L Q + + + +D + R C ++ DRP+ + Sbjct: 747 VEN-------SEIYDYLRQGNRLKQPVDFLDGLYSLMSR--------CWELNPRDRPSFA 791 Query: 292 DTIEMLEGSVDALQMPSRP 236 + E LE ++ AL P Sbjct: 792 ELREDLENTLKALPPAQEP 810
>UFO_HUMAN (P30530) Tyrosine-protein kinase receptor UFO precursor (EC 2.7.10.1)| (AXL oncogene) Length = 887 Score = 38.9 bits (89), Expect = 0.014 Identities = 37/139 (26%), Positives = 64/139 (46%) Frame = -3 Query: 652 KLYPRDTSFVPSRALRGTIGYIAPEMISRSFGVISSKSDVYSFGMLLLEMAGGRRNADPN 473 K+Y D + R + + +IA E ++ V +SKSDV+SFG+ + E+A + P Sbjct: 689 KIYNGDY-YRQGRIAKMPVKWIAIESLADR--VYTSKSDVWSFGVTMWEIATRGQTPYPG 745 Query: 472 AANTSKAYYPSWVYDRLIQQDHVGEISTHVDVEMHELERKLCIVGLWCIQMKSNDRPTMS 293 N S +YD L Q + + + + +D + R C ++ DRP+ + Sbjct: 746 VEN-------SEIYDYLRQGNRLKQPADCLDGLYALMSR--------CWELNPQDRPSFT 790 Query: 292 DTIEMLEGSVDALQMPSRP 236 + E LE ++ AL P Sbjct: 791 ELREDLENTLKALPPAQEP 809
>BRL2_ARATH (Q9ZPS9) Serine/threonine-protein kinase BRI1-like 2 precursor (EC| 2.7.11.1) (BRASSINOSTEROID INSENSITIVE 1-like protein 2) (Protein VASCULAR HIGHWAY 1) Length = 1143 Score = 38.5 bits (88), Expect = 0.018 Identities = 35/126 (27%), Positives = 55/126 (43%), Gaps = 14/126 (11%) Frame = -3 Query: 610 LRGTIGYIAPEMISRSFGVISSKSDVYSFGMLLLEMAGGRRN------ADPNAANTSKAY 449 L GT GY+ PE +SF ++K DVYS G+++LE+ G+R D N SK Sbjct: 1003 LAGTPGYVPPEYY-QSFRC-TAKGDVYSIGVVMLEILSGKRPTDKEEFGDTNLVGWSKMK 1060 Query: 448 YPSWVYDRLIQQDHVGEISTHVDVEMHELERKLCI--------VGLWCIQMKSNDRPTMS 293 + +I +D + E S+ E E + + + L C+ + RP M Sbjct: 1061 AREGKHMEVIDEDLLKEGSSESLNEKEGFEGGVIVKEMLRYLEIALRCVDDFPSKRPNML 1120 Query: 292 DTIEML 275 + L Sbjct: 1121 QVVASL 1126
>MKH1_SCHPO (Q10407) MAP kinase kinase kinase mkh1 (EC 2.7.11.25)| Length = 1116 Score = 38.5 bits (88), Expect = 0.018 Identities = 18/42 (42%), Positives = 29/42 (69%) Frame = -3 Query: 613 ALRGTIGYIAPEMISRSFGVISSKSDVYSFGMLLLEMAGGRR 488 +++G+I ++APE+I S+K DV+S G ++LEM GRR Sbjct: 991 SMQGSIFWMAPEVIHNDHQGYSAKVDVWSLGCVVLEMLAGRR 1032
>LCK_AOTNA (Q5PXS1) Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2)| (p56-LCK) (Lymphocyte cell-specific protein-tyrosine kinase) Length = 508 Score = 37.0 bits (84), Expect = 0.052 Identities = 35/134 (26%), Positives = 56/134 (41%) Frame = -3 Query: 637 DTSFVPSRALRGTIGYIAPEMISRSFGVISSKSDVYSFGMLLLEMAGGRRNADPNAANTS 458 D + + I + APE I+ +G + KSDV+SFG+LL E+ R P N Sbjct: 390 DNEYTAREGAKFPIKWTAPEAIN--YGTFTIKSDVWSFGILLTEIVTHGRIPYPGMTNPE 447 Query: 457 KAYYPSWVYDRLIQQDHVGEISTHVDVEMHELERKLCIVGLWCIQMKSNDRPTMSDTIEM 278 Y R+++ D+ E E++ L + C + + DRPT + Sbjct: 448 VIQNLERGY-RMVRPDNCPE-------ELYHLM-------MLCWKERPEDRPTFDYLRSV 492 Query: 277 LEGSVDALQMPSRP 236 LE A + +P Sbjct: 493 LEDFFTATEGQYQP 506
>BLK_HUMAN (P51451) Tyrosine-protein kinase BLK (EC 2.7.10.2) (B lymphocyte| kinase) (p55-BLK) Length = 504 Score = 37.0 bits (84), Expect = 0.052 Identities = 21/58 (36%), Positives = 32/58 (55%) Frame = -3 Query: 637 DTSFVPSRALRGTIGYIAPEMISRSFGVISSKSDVYSFGMLLLEMAGGRRNADPNAAN 464 D+ + + I + APE I FGV + K+DV+SFG+LL+E+ R P +N Sbjct: 385 DSEYTAQEGAKFPIKWTAPEAIH--FGVFTIKADVWSFGVLLMEVVTYGRVPYPGMSN 440
>GCN2_SCHPO (Q9HGN1) Serine/threonine-protein kinase gcn2 (EC 2.7.11.1)| Length = 1576 Score = 36.6 bits (83), Expect = 0.068 Identities = 18/35 (51%), Positives = 25/35 (71%), Gaps = 1/35 (2%) Frame = -3 Query: 604 GTIGYIAPEMISRSFGV-ISSKSDVYSFGMLLLEM 503 GT Y+APE++SR GV +K D+YS G++L EM Sbjct: 822 GTALYVAPELLSRRNGVRYDAKVDMYSLGIILFEM 856 Score = 32.7 bits (73), Expect = 0.98 Identities = 14/34 (41%), Positives = 21/34 (61%) Frame = -3 Query: 595 GYIAPEMISRSFGVISSKSDVYSFGMLLLEMAGG 494 G PE+ SF S K+D++ FG+L+L+M G Sbjct: 425 GLYPPEVSESSFAAASRKTDIWCFGLLVLQMLCG 458
>M3K8_RAT (Q63562) Mitogen-activated protein kinase kinase kinase 8 (EC| 2.7.11.25) (Tumor progression locus 2) (TPL-2) Length = 467 Score = 36.6 bits (83), Expect = 0.068 Identities = 32/111 (28%), Positives = 51/111 (45%), Gaps = 1/111 (0%) Frame = -3 Query: 610 LRGTIGYIAPEMI-SRSFGVISSKSDVYSFGMLLLEMAGGRRNADPNAANTSKAYYPSWV 434 LRGT Y++PE+I R S+K+D+YS G L+ M G P ++ YPS++ Sbjct: 287 LRGTEIYMSPEVILCRGH---STKADIYSLGATLIHMQTG---TPPWVKRYPRSAYPSYL 340 Query: 433 YDRLIQQDHVGEISTHVDVEMHELERKLCIVGLWCIQMKSNDRPTMSDTIE 281 Y Q + +I+ M EL ++ N RP +D ++ Sbjct: 341 YIIHKQAPPLEDIAGDCSPGMRELIEA-------ALERNPNHRPKAADLLK 384
>M3K8_MOUSE (Q07174) Mitogen-activated protein kinase kinase kinase 8 (EC| 2.7.11.25) (COT proto-oncogene serine/threonine-protein kinase) (C-COT) (Cancer Osaka thyroid oncogene) Length = 467 Score = 36.6 bits (83), Expect = 0.068 Identities = 32/111 (28%), Positives = 51/111 (45%), Gaps = 1/111 (0%) Frame = -3 Query: 610 LRGTIGYIAPEMI-SRSFGVISSKSDVYSFGMLLLEMAGGRRNADPNAANTSKAYYPSWV 434 LRGT Y++PE+I R S+K+D+YS G L+ M G P ++ YPS++ Sbjct: 287 LRGTEIYMSPEVILCRGH---STKADIYSLGATLIHMQTG---TPPWVKRYPRSAYPSYL 340 Query: 433 YDRLIQQDHVGEISTHVDVEMHELERKLCIVGLWCIQMKSNDRPTMSDTIE 281 Y Q + +I+ M EL ++ N RP +D ++ Sbjct: 341 YIIHKQAPPLEDIAGDCSPGMRELIEA-------ALERNPNHRPKAADLLK 384
>M3K8_HUMAN (P41279) Mitogen-activated protein kinase kinase kinase 8 (EC| 2.7.11.25) (COT proto-oncogene serine/threonine-protein kinase) (C-COT) (Cancer Osaka thyroid oncogene) Length = 467 Score = 36.6 bits (83), Expect = 0.068 Identities = 32/111 (28%), Positives = 51/111 (45%), Gaps = 1/111 (0%) Frame = -3 Query: 610 LRGTIGYIAPEMI-SRSFGVISSKSDVYSFGMLLLEMAGGRRNADPNAANTSKAYYPSWV 434 LRGT Y++PE+I R S+K+D+YS G L+ M G P ++ YPS++ Sbjct: 287 LRGTEIYMSPEVILCRGH---STKADIYSLGATLIHMQTG---TPPWVKRYPRSAYPSYL 340 Query: 433 YDRLIQQDHVGEISTHVDVEMHELERKLCIVGLWCIQMKSNDRPTMSDTIE 281 Y Q + +I+ M EL ++ N RP +D ++ Sbjct: 341 YIIHKQAPPLEDIADDCSPGMRELIEA-------SLERNPNHRPRAADLLK 384
>KIN31_CAEEL (P34265) Probable tyrosine-protein kinase kin-31 (EC 2.7.10.2)| Length = 437 Score = 36.6 bits (83), Expect = 0.068 Identities = 33/115 (28%), Positives = 54/115 (46%), Gaps = 3/115 (2%) Frame = -3 Query: 607 RGTIGYIAPEMIS--RSFGVISSKSDVYSFGMLLLEMAGGRRNADPNAANTSKAYYPSWV 434 RGTI + PE S R V S K+DV+++G+L E+ A+P YP Sbjct: 279 RGTIYQLHPETKSPIRWLAVCSQKTDVWAYGILCWEIFNN--GAEP---------YPGLT 327 Query: 433 YDRLIQQDHVGEISTHVDVEMHELER-KLCIVGLWCIQMKSNDRPTMSDTIEMLE 272 + + +Q ++ + H+L ++ + C NDRPTMSD ++L+ Sbjct: 328 ANEVAKQ-----VTDGYRMPPHQLAAPEVQALMTRCCAENPNDRPTMSDVAQILQ 377
>GCY3E_DROME (Q07553) Guanylate cyclase 32E precursor (EC 4.6.1.2)| Length = 1163 Score = 36.2 bits (82), Expect = 0.088 Identities = 32/124 (25%), Positives = 56/124 (45%), Gaps = 2/124 (1%) Frame = -3 Query: 589 IAPEMISRSF--GVISSKSDVYSFGMLLLEMAGGRRNADPNAANTSKAYYPSWVYDRLIQ 416 +APE++ ++ G S K DVYSFG+LL EM GR+ + A + + ++Q Sbjct: 696 MAPELLRDAYRPGRGSQKGDVYSFGILLYEMI-GRKGPWGDTAYSKEEIIQFVKCPEMLQ 754 Query: 415 QDHVGEISTHVDVEMHELERKLCIVGLWCIQMKSNDRPTMSDTIEMLEGSVDALQMPSRP 236 TH +++ + RK C+ W ++ P + I ++ + LQ +P Sbjct: 755 HGVFRPALTHTHLDIPDYIRK-CLCQCW------DEDPEVRPDIRLVRMHLKELQAGLKP 807 Query: 235 FFCD 224 D Sbjct: 808 NIFD 811
>LYN_MOUSE (P25911) Tyrosine-protein kinase Lyn (EC 2.7.10.2)| Length = 511 Score = 36.2 bits (82), Expect = 0.088 Identities = 24/64 (37%), Positives = 33/64 (51%), Gaps = 7/64 (10%) Frame = -3 Query: 637 DTSFVPSRALRGTIGYIAPEMISRSFGVISSKSDVYSFGMLLLEMA-------GGRRNAD 479 D + + I + APE I+ FG + KSDV+SFG+LL E+ GR NAD Sbjct: 393 DNEYTAREGAKFPIKWTAPEAIN--FGCFTIKSDVWSFGILLYEIVTYGKIPYPGRTNAD 450 Query: 478 PNAA 467 +A Sbjct: 451 VMSA 454
>ANKK1_HUMAN (Q8NFD2) Ankyrin repeat and protein kinase domain-containing| protein 1 (EC 2.7.11.1) (Protein kinase PKK2) (X-kinase) (SgK288) Length = 765 Score = 36.2 bits (82), Expect = 0.088 Identities = 17/42 (40%), Positives = 24/42 (57%) Frame = -3 Query: 628 FVPSRALRGTIGYIAPEMISRSFGVISSKSDVYSFGMLLLEM 503 ++ ALRG + YI PEM S K DVYSF +++ E+ Sbjct: 178 YIERSALRGMLSYIPPEMFLESNKAPGPKYDVYSFAIVIWEL 219
>CPK11_ARATH (O22932) CBL-interacting serine/threonine-protein kinase 11 (EC| 2.7.11.1) (SOS2-like protein kinase PKS5) (SOS-interacting protein 4) (SNF1-related kinase 3.22) Length = 435 Score = 36.2 bits (82), Expect = 0.088 Identities = 25/66 (37%), Positives = 35/66 (53%), Gaps = 7/66 (10%) Frame = -3 Query: 610 LRGTIGYIAPEMISRSFGVISSKSDVYSFGMLLLEM-AGGRRNADPNAANTSKAYY---- 446 L GT Y+APE++S+ G +K DV+S G++L + AG DPN N K Y Sbjct: 182 LCGTPAYVAPEILSKK-GYEGAKVDVWSCGIVLFVLVAGYLPFNDPNVMNMYKKIYKGEY 240 Query: 445 --PSWV 434 P W+ Sbjct: 241 RFPRWM 246
>RIPK3_MOUSE (Q9QZL0) Receptor-interacting serine/threonine-protein kinase 3 (EC| 2.7.11.1) (RIP-like protein kinase 3) (Receptor-interacting protein 3) (RIP-3) (mRIP3) Length = 486 Score = 35.8 bits (81), Expect = 0.12 Identities = 18/43 (41%), Positives = 26/43 (60%) Frame = -3 Query: 619 SRALRGTIGYIAPEMISRSFGVISSKSDVYSFGMLLLEMAGGR 491 SR GT+ Y+ PE++ + S SDVYSFG+L+ + GR Sbjct: 181 SRDSGGTLAYLDPELLFKVNLKASKASDVYSFGILVWAVLAGR 223
>LYN_RAT (Q07014) Tyrosine-protein kinase Lyn (EC 2.7.10.2)| Length = 511 Score = 35.8 bits (81), Expect = 0.12 Identities = 23/60 (38%), Positives = 31/60 (51%), Gaps = 7/60 (11%) Frame = -3 Query: 637 DTSFVPSRALRGTIGYIAPEMISRSFGVISSKSDVYSFGMLLLEMA-------GGRRNAD 479 D + + I + APE I+ FG + KSDV+SFG+LL E+ GR NAD Sbjct: 393 DNEYTAREGAKFPIKWTAPEAIN--FGCFTIKSDVWSFGILLYEIVTYGKIPYPGRTNAD 450
>LYN_HUMAN (P07948) Tyrosine-protein kinase Lyn (EC 2.7.10.2)| Length = 511 Score = 35.8 bits (81), Expect = 0.12 Identities = 23/60 (38%), Positives = 31/60 (51%), Gaps = 7/60 (11%) Frame = -3 Query: 637 DTSFVPSRALRGTIGYIAPEMISRSFGVISSKSDVYSFGMLLLEMA-------GGRRNAD 479 D + + I + APE I+ FG + KSDV+SFG+LL E+ GR NAD Sbjct: 393 DNEYTAREGAKFPIKWTAPEAIN--FGCFTIKSDVWSFGILLYEIVTYGKIPYPGRTNAD 450
>LCK_SAISC (Q95KR7) Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2)| (p56-LCK) (Lymphocyte cell-specific protein-tyrosine kinase) Length = 508 Score = 35.8 bits (81), Expect = 0.12 Identities = 33/134 (24%), Positives = 54/134 (40%) Frame = -3 Query: 637 DTSFVPSRALRGTIGYIAPEMISRSFGVISSKSDVYSFGMLLLEMAGGRRNADPNAANTS 458 D + + I + APE I+ +G + KSDV+SFG+L+ E+ Sbjct: 390 DNEYTAREGAKFPIKWTAPEAIN--YGTFTIKSDVWSFGILMTEI-----------VTHG 436 Query: 457 KAYYPSWVYDRLIQQDHVGEISTHVDVEMHELERKLCIVGLWCIQMKSNDRPTMSDTIEM 278 + YP +IQ G D EL + + + C + + +DRPT + Sbjct: 437 RIPYPGMTNPEVIQNLERGYRMPRPDNCPEELYKLM----MQCWRERPDDRPTFDYLRSV 492 Query: 277 LEGSVDALQMPSRP 236 LE A + +P Sbjct: 493 LEDFFTATEGQYQP 506
>LCK_MOUSE (P06240) Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2)| (p56-LCK) (Lymphocyte cell-specific protein-tyrosine kinase) (LSK) Length = 508 Score = 35.8 bits (81), Expect = 0.12 Identities = 34/134 (25%), Positives = 56/134 (41%) Frame = -3 Query: 637 DTSFVPSRALRGTIGYIAPEMISRSFGVISSKSDVYSFGMLLLEMAGGRRNADPNAANTS 458 D + + I + APE I+ +G + KSDV+SFG+LL E+ R P N Sbjct: 390 DNEYTAREGAKFPIKWTAPEAIN--YGTFTIKSDVWSFGILLTEIVTHGRIPYPGMTNPE 447 Query: 457 KAYYPSWVYDRLIQQDHVGEISTHVDVEMHELERKLCIVGLWCIQMKSNDRPTMSDTIEM 278 Y R+++ D+ E E++ L + C + + DRPT + Sbjct: 448 VIQNLERGY-RMVRPDNCPE-------ELYHLM-------MLCWKERPEDRPTFDYLRSV 492 Query: 277 LEGSVDALQMPSRP 236 L+ A + +P Sbjct: 493 LDDFFTATEGQYQP 506
>SRC64_DROME (P00528) Tyrosine-protein kinase Src64B (EC 2.7.10.2) (Dsrc64)| Length = 552 Score = 35.8 bits (81), Expect = 0.12 Identities = 18/45 (40%), Positives = 28/45 (62%) Frame = -3 Query: 637 DTSFVPSRALRGTIGYIAPEMISRSFGVISSKSDVYSFGMLLLEM 503 D + P + R + + APE I +G S KSDV+S+G+LL+E+ Sbjct: 431 DDEYCPKQGSRFPVKWTAPEAII--YGKFSIKSDVWSYGILLMEL 473
>PK1_STRTO (Q9KIG4) Serine/threonine-protein kinase PK-1 (EC 2.7.11.1)| (stoPK-1) Length = 641 Score = 35.8 bits (81), Expect = 0.12 Identities = 18/42 (42%), Positives = 24/42 (57%) Frame = -3 Query: 604 GTIGYIAPEMISRSFGVISSKSDVYSFGMLLLEMAGGRRNAD 479 GT+ Y+APE I G + DVY+ G+LL EM G + D Sbjct: 178 GTVSYLAPEQIEH--GTADPRVDVYACGILLYEMLTGEKPHD 217
>ITK_MOUSE (Q03526) Tyrosine-protein kinase ITK/TSK (EC 2.7.10.2)| (T-cell-specific kinase) (IL-2-inducible T-cell kinase) (Kinase EMT) (Kinase TLK) Length = 625 Score = 35.8 bits (81), Expect = 0.12 Identities = 33/130 (25%), Positives = 52/130 (40%), Gaps = 3/130 (2%) Frame = -3 Query: 637 DTSFVPSRALRGTIGYIAPEMISRSFGVISSKSDVYSFGMLLLEMAGGRRNADPNAANTS 458 D + S + + + +PE+ S F SSKSDV+SFG+L+ E+ + N +N+ Sbjct: 514 DDQYTSSTGTKFPVKWASPEVFS--FSRYSSKSDVWSFGVLMWEVFSEGKIPYENRSNSE 571 Query: 457 KAYYPSW---VYDRLIQQDHVGEISTHVDVEMHELERKLCIVGLWCIQMKSNDRPTMSDT 287 S +Y + HV +I H C + K DRP S Sbjct: 572 VVEDISTGFRLYKPRLASCHVYQIMNH------------------CWKEKPEDRPPFSQL 613 Query: 286 IEMLEGSVDA 257 + L +A Sbjct: 614 LSQLAEIAEA 623
>HCK_RAT (P50545) Tyrosine-protein kinase HCK (EC 2.7.10.2) (p56-HCK)| (Hemopoietic cell kinase) Length = 502 Score = 35.8 bits (81), Expect = 0.12 Identities = 21/58 (36%), Positives = 31/58 (53%) Frame = -3 Query: 637 DTSFVPSRALRGTIGYIAPEMISRSFGVISSKSDVYSFGMLLLEMAGGRRNADPNAAN 464 D + + I + APE I+ FG + KSDV+SFG+LL+E+ R P +N Sbjct: 384 DNEYTAREGAKFPIKWTAPEAIN--FGSFTIKSDVWSFGILLMEIVTYGRIPYPGMSN 439
>IRAK1_HUMAN (P51617) Interleukin-1 receptor-associated kinase 1 (EC 2.7.11.1)| (IRAK-1) Length = 712 Score = 35.8 bits (81), Expect = 0.12 Identities = 20/62 (32%), Positives = 35/62 (56%), Gaps = 1/62 (1%) Frame = -3 Query: 643 PRDTSFVP-SRALRGTIGYIAPEMISRSFGVISSKSDVYSFGMLLLEMAGGRRNADPNAA 467 P +S V ++ +RGT+ Y+ E I G ++ +D +SFG+++LE G+R + A Sbjct: 372 PSQSSMVARTQTVRGTLAYLPEEYIKT--GRLAVDTDTFSFGVVVLETLAGQRAVKTHGA 429 Query: 466 NT 461 T Sbjct: 430 RT 431
>HCK_HUMAN (P08631) Tyrosine-protein kinase HCK (EC 2.7.10.2)| (p59-HCK/p60-HCK) (Hemopoietic cell kinase) Length = 525 Score = 35.8 bits (81), Expect = 0.12 Identities = 21/58 (36%), Positives = 31/58 (53%) Frame = -3 Query: 637 DTSFVPSRALRGTIGYIAPEMISRSFGVISSKSDVYSFGMLLLEMAGGRRNADPNAAN 464 D + + I + APE I+ FG + KSDV+SFG+LL+E+ R P +N Sbjct: 407 DNEYTAREGAKFPIKWTAPEAIN--FGSFTIKSDVWSFGILLMEIVTYGRIPYPGMSN 462
>HCK_MOUSE (P08103) Tyrosine-protein kinase HCK (EC 2.7.10.2)| (p56-HCK/p59-HCK) (Hemopoietic cell kinase) (B-cell/myeloid kinase) (BMK) Length = 523 Score = 35.8 bits (81), Expect = 0.12 Identities = 21/58 (36%), Positives = 31/58 (53%) Frame = -3 Query: 637 DTSFVPSRALRGTIGYIAPEMISRSFGVISSKSDVYSFGMLLLEMAGGRRNADPNAAN 464 D + + I + APE I+ FG + KSDV+SFG+LL+E+ R P +N Sbjct: 405 DNEYTAREGAKFPIKWTAPEAIN--FGSFTIKSDVWSFGILLMEIVTYGRIPYPGMSN 460
>ANKK1_MOUSE (Q8BZ25) Ankyrin repeat and protein kinase domain-containing| protein 1 (EC 2.7.11.1) Length = 745 Score = 35.4 bits (80), Expect = 0.15 Identities = 16/42 (38%), Positives = 25/42 (59%) Frame = -3 Query: 628 FVPSRALRGTIGYIAPEMISRSFGVISSKSDVYSFGMLLLEM 503 ++ ALRGT+ YI PEM + + DVYSF +++ E+ Sbjct: 190 YIERSALRGTLSYIPPEMFLENNKAPGPEYDVYSFAIVIWEI 231
>TMKL1_ARATH (P33543) Putative kinase-like protein TMKL1 precursor| Length = 674 Score = 35.4 bits (80), Expect = 0.15 Identities = 28/112 (25%), Positives = 49/112 (43%), Gaps = 4/112 (3%) Frame = -3 Query: 595 GYIAPEMISRSFGVISSKSDVYSFGMLLLEMAGGRRNADPNAANTSKAYYPSWVYDRLIQ 416 GY APE+ + +SDVY+FG+LLLE+ G++ PS V +++ Sbjct: 541 GYKAPEL--HKMKKCNPRSDVYAFGILLLEILMGKKPGKSGRNGNEFVDLPSLVKAAVLE 598 Query: 415 QDHVG----EISTHVDVEMHELERKLCIVGLWCIQMKSNDRPTMSDTIEMLE 272 + + E + M E + + C + RP+M + ++ LE Sbjct: 599 ETTMEVFDLEAMKGIRSPMEEGLVHALKLAMGCCAPVTTVRPSMEEVVKQLE 650
>LRRK1_MOUSE (Q3UHC2) Leucine-rich repeat serine/threonine-protein kinase 1 (EC| 2.7.11.1) Length = 2014 Score = 35.4 bits (80), Expect = 0.15 Identities = 19/43 (44%), Positives = 27/43 (62%) Frame = -3 Query: 610 LRGTIGYIAPEMISRSFGVISSKSDVYSFGMLLLEMAGGRRNA 482 + GT GY APE+ R V K D++S+GM+L E+ G+R A Sbjct: 1424 VEGTPGYQAPEIRPRI--VYDEKVDMFSYGMVLYELLSGQRPA 1464
>CTR1_ARATH (Q05609) Serine/threonine-protein kinase CTR1 (EC 2.7.11.1)| Length = 821 Score = 35.4 bits (80), Expect = 0.15 Identities = 18/45 (40%), Positives = 31/45 (68%) Frame = -3 Query: 634 TSFVPSRALRGTIGYIAPEMISRSFGVISSKSDVYSFGMLLLEMA 500 ++F+ S++ GT ++APE++ + KSDVYSFG++L E+A Sbjct: 703 STFLSSKSAAGTPEWMAPEVLRDEPS--NEKSDVYSFGVILWELA 745
>LRRK1_HUMAN (Q38SD2) Leucine-rich repeat serine/threonine-protein kinase 1 (EC| 2.7.11.1) Length = 2038 Score = 35.4 bits (80), Expect = 0.15 Identities = 19/43 (44%), Positives = 27/43 (62%) Frame = -3 Query: 610 LRGTIGYIAPEMISRSFGVISSKSDVYSFGMLLLEMAGGRRNA 482 + GT GY APE+ R V K D++S+GM+L E+ G+R A Sbjct: 1447 VEGTPGYQAPEIRPRI--VYDEKVDMFSYGMVLYELLSGQRPA 1487
>HCK_MACFA (Q95M30) Tyrosine-protein kinase HCK (EC 2.7.10.2) (p56-HCK)| (Hemopoietic cell kinase) Length = 503 Score = 35.0 bits (79), Expect = 0.20 Identities = 21/58 (36%), Positives = 31/58 (53%) Frame = -3 Query: 637 DTSFVPSRALRGTIGYIAPEMISRSFGVISSKSDVYSFGMLLLEMAGGRRNADPNAAN 464 D + + I + APE I+ FG + KSDV+SFG+LL+E+ R P +N Sbjct: 385 DNEYTAREGAKFPIKWTAPEAIN--FGSSTIKSDVWSFGILLMEIVTYGRIPYPGMSN 440
>KSG1_SCHPO (Q12701) Serine/threonine-protein kinase ksg1 (EC 2.7.11.1)| Length = 592 Score = 35.0 bits (79), Expect = 0.20 Identities = 15/43 (34%), Positives = 28/43 (65%) Frame = -3 Query: 619 SRALRGTIGYIAPEMISRSFGVISSKSDVYSFGMLLLEMAGGR 491 SR+ GT Y++PE++S + + SD+++FG +L +M G+ Sbjct: 269 SRSFVGTARYVSPEVLSDK--IAGTASDIWAFGCILFQMLAGK 309
>PKN5_MYXXA (P54737) Serine/threonine-protein kinase pkn5 (EC 2.7.11.1)| Length = 380 Score = 35.0 bits (79), Expect = 0.20 Identities = 19/55 (34%), Positives = 29/55 (52%) Frame = -3 Query: 655 AKLYPRDTSFVPSRALRGTIGYIAPEMISRSFGVISSKSDVYSFGMLLLEMAGGR 491 AK D + + L GT Y+APE I + ++D+YS G++L E+ GR Sbjct: 266 AKFLADDAAITEAGKLVGTYRYMAPEQILGE--PLDGRADLYSLGVILYELLSGR 318
>JIL1_DROME (Q9V3I5) Chromosomal serine/threonine-protein kinase JIL-1 (EC| 2.7.11.1) Length = 1207 Score = 34.7 bits (78), Expect = 0.26 Identities = 28/110 (25%), Positives = 46/110 (41%), Gaps = 1/110 (0%) Frame = -3 Query: 607 RGTIGYIAPEMISRSFGVISSKS-DVYSFGMLLLEMAGGRRNADPNAANTSKAYYPSWVY 431 R T+ Y PEM++ + V S + D+Y G L M G R P N + + + Sbjct: 777 RYTLDYAPPEMLADANLVTYSPAVDIYGLGATLYTMLVGHR---PYRQNEDDVDHSAAAH 833 Query: 430 DRLIQQDHVGEISTHVDVEMHELERKLCIVGLWCIQMKSNDRPTMSDTIE 281 L ++ G + + + WC+Q DRPT+SD ++ Sbjct: 834 HELRKRMRRGTFNQR-SMRWESASPAFRHLVSWCLQRDPADRPTLSDILD 882
>LIMK1_RAT (P53669) LIM domain kinase 1 (EC 2.7.11.1) (LIMK-1)| Length = 647 Score = 34.7 bits (78), Expect = 0.26 Identities = 25/55 (45%), Positives = 35/55 (63%), Gaps = 5/55 (9%) Frame = -3 Query: 622 PSRALRGTIG----YIAPEMIS-RSFGVISSKSDVYSFGMLLLEMAGGRRNADPN 473 P R R T+ ++APEMI+ RS+ K DV+SFG++L E+ GR NADP+ Sbjct: 501 PDRKKRYTVVGNPYWMAPEMINGRSY---DEKVDVFSFGIVLCEII-GRVNADPD 551
>LIMK1_MOUSE (P53668) LIM domain kinase 1 (EC 2.7.11.1) (LIMK-1) (KIZ-1)| Length = 647 Score = 34.7 bits (78), Expect = 0.26 Identities = 25/55 (45%), Positives = 35/55 (63%), Gaps = 5/55 (9%) Frame = -3 Query: 622 PSRALRGTIG----YIAPEMIS-RSFGVISSKSDVYSFGMLLLEMAGGRRNADPN 473 P R R T+ ++APEMI+ RS+ K DV+SFG++L E+ GR NADP+ Sbjct: 501 PDRKKRYTVVGNPYWMAPEMINGRSY---DEKVDVFSFGIVLCEII-GRVNADPD 551
>LIMK1_HUMAN (P53667) LIM domain kinase 1 (EC 2.7.11.1) (LIMK-1)| Length = 647 Score = 34.7 bits (78), Expect = 0.26 Identities = 25/55 (45%), Positives = 35/55 (63%), Gaps = 5/55 (9%) Frame = -3 Query: 622 PSRALRGTIG----YIAPEMIS-RSFGVISSKSDVYSFGMLLLEMAGGRRNADPN 473 P R R T+ ++APEMI+ RS+ K DV+SFG++L E+ GR NADP+ Sbjct: 501 PDRKKRYTVVGNPYWMAPEMINGRSY---DEKVDVFSFGIVLCEII-GRVNADPD 551
>M3K4_MOUSE (O08648) Mitogen-activated protein kinase kinase kinase 4 (EC| 2.7.11.25) (MAPK/ERK kinase kinase 4) (MEK kinase 4) (MEKK 4) Length = 1597 Score = 34.7 bits (78), Expect = 0.26 Identities = 16/40 (40%), Positives = 28/40 (70%), Gaps = 1/40 (2%) Frame = -3 Query: 604 GTIGYIAPEMISRSFGVISSK-SDVYSFGMLLLEMAGGRR 488 GT Y+APE+I+R+ G + +D++S G +++EM G+R Sbjct: 1493 GTAAYMAPEVITRAKGEGHGRAADIWSLGCVVIEMVTGKR 1532
>M3K4_HUMAN (Q9Y6R4) Mitogen-activated protein kinase kinase kinase 4 (EC| 2.7.11.25) (MAPK/ERK kinase kinase 4) (MEK kinase 4) (MEKK 4) (MAP three kinase 1) Length = 1607 Score = 34.7 bits (78), Expect = 0.26 Identities = 16/40 (40%), Positives = 28/40 (70%), Gaps = 1/40 (2%) Frame = -3 Query: 604 GTIGYIAPEMISRSFGVISSK-SDVYSFGMLLLEMAGGRR 488 GT Y+APE+I+R+ G + +D++S G +++EM G+R Sbjct: 1503 GTAAYMAPEVITRAKGEGHGRAADIWSLGCVVIEMVTGKR 1542
>ITK_HUMAN (Q08881) Tyrosine-protein kinase ITK/TSK (EC 2.7.10.2)| (T-cell-specific kinase) (Tyrosine-protein kinase Lyk) (Kinase EMT) Length = 620 Score = 34.7 bits (78), Expect = 0.26 Identities = 31/124 (25%), Positives = 50/124 (40%), Gaps = 3/124 (2%) Frame = -3 Query: 637 DTSFVPSRALRGTIGYIAPEMISRSFGVISSKSDVYSFGMLLLEMAGGRRNADPNAANTS 458 D + S + + + +PE+ S F SSKSDV+SFG+L+ E+ + N +N+ Sbjct: 509 DDQYTSSTGTKFPVKWASPEVFS--FSRYSSKSDVWSFGVLMWEVFSEGKIPYENRSNSE 566 Query: 457 KAYYPSW---VYDRLIQQDHVGEISTHVDVEMHELERKLCIVGLWCIQMKSNDRPTMSDT 287 S +Y + HV +I H C + + DRP S Sbjct: 567 VVEDISTGFRLYKPRLASTHVYQIMNH------------------CWKERPEDRPAFSRL 608 Query: 286 IEML 275 + L Sbjct: 609 LRQL 612
>YR831_MIMIV (Q7T6Y2) Putative serine/threonine-protein kinase/receptor R831| precursor (EC 2.7.11.1) Length = 1624 Score = 34.7 bits (78), Expect = 0.26 Identities = 17/34 (50%), Positives = 25/34 (73%) Frame = -3 Query: 604 GTIGYIAPEMISRSFGVISSKSDVYSFGMLLLEM 503 GTI +IAPE+++ S V +DVYSFG++L E+ Sbjct: 947 GTIHWIAPEILNDSTEVDYILADVYSFGIILWEL 980
>PAK6_HUMAN (Q9NQU5) Serine/threonine-protein kinase PAK 6 (EC 2.7.11.1)| (p21-activated kinase 6) (PAK-6) (PAK-5) Length = 681 Score = 34.7 bits (78), Expect = 0.26 Identities = 19/45 (42%), Positives = 33/45 (73%), Gaps = 1/45 (2%) Frame = -3 Query: 625 VPSR-ALRGTIGYIAPEMISRSFGVISSKSDVYSFGMLLLEMAGG 494 VP R +L GT ++APE+ISRS + +++ D++S G++++EM G Sbjct: 555 VPKRKSLVGTPYWMAPEVISRS--LYATEVDIWSLGIMVIEMVDG 597
>FGR_FSVGR (P00544) Tyrosine-protein kinase transforming protein Fgr (EC| 2.7.10.2) Length = 545 Score = 34.3 bits (77), Expect = 0.34 Identities = 21/58 (36%), Positives = 30/58 (51%) Frame = -3 Query: 637 DTSFVPSRALRGTIGYIAPEMISRSFGVISSKSDVYSFGMLLLEMAGGRRNADPNAAN 464 D + P + + I + APE + FG + KSDV+SFG+LL E+ R P N Sbjct: 432 DNEYNPRQGAKFPIKWTAPE--AALFGRFTIKSDVWSFGILLTELISKGRVPYPGMNN 487
>FGFR1_DROME (Q07407) Fibroblast growth factor receptor homolog 1 precursor (EC| 2.7.10.1) (Protein heartless) Length = 729 Score = 34.3 bits (77), Expect = 0.34 Identities = 31/142 (21%), Positives = 60/142 (42%), Gaps = 9/142 (6%) Frame = -3 Query: 598 IGYIAPEMISRSFGVISSKSDVYSFGMLLLEMAGGRRNADPNAANTSKAYYPSWVYDRLI 419 I ++APE + F SKSDV+S+G+LL E+ + P + + Y R+ Sbjct: 597 IKWMAPESLQEKF--YDSKSDVWSYGILLWEIMTYGQQPYPTIMSAEELYTYLMSGQRM- 653 Query: 418 QQDHVGEISTHVDVEMHELERKLCIVGLWCIQMKSNDRPTMSDTIEMLEG---------S 266 + + S ++ + M + C ++DRP ++ +E ++ Sbjct: 654 --EKPAKCSMNIYILMRQ-----------CWHFNADDRPPFTEIVEYMDKLLQTKEDYLD 700 Query: 265 VDALQMPSRPFFCDEGHVQTED 200 VD + + P DE +T++ Sbjct: 701 VDIANLDTPPSTSDEEEDETDN 722
>SRMS_MOUSE (Q62270) Tyrosine-protein kinase Srms (EC 2.7.10.2) (PTK70)| Length = 496 Score = 34.3 bits (77), Expect = 0.34 Identities = 18/46 (39%), Positives = 29/46 (63%) Frame = -3 Query: 640 RDTSFVPSRALRGTIGYIAPEMISRSFGVISSKSDVYSFGMLLLEM 503 +D + PS + + + APE + ++ V S KSDV+SFG+LL E+ Sbjct: 380 KDDVYSPSSGSKIPVKWTAPE--AANYRVFSQKSDVWSFGILLYEV 423
>BLK_MOUSE (P16277) Tyrosine-protein kinase BLK (EC 2.7.10.2) (B lymphocyte| kinase) (p55-BLK) Length = 498 Score = 34.3 bits (77), Expect = 0.34 Identities = 20/58 (34%), Positives = 31/58 (53%) Frame = -3 Query: 637 DTSFVPSRALRGTIGYIAPEMISRSFGVISSKSDVYSFGMLLLEMAGGRRNADPNAAN 464 D+ + + I + APE I FGV + K+DV+SFG+LL+ + R P +N Sbjct: 379 DSEYTAQEGAKFPIKWTAPEAIH--FGVFTIKADVWSFGVLLMVIVTYGRVPYPGMSN 434
>ABL_DROME (P00522) Tyrosine-protein kinase Abl (EC 2.7.10.2) (Abelson| protein) (D-ash) Length = 1620 Score = 34.3 bits (77), Expect = 0.34 Identities = 32/123 (26%), Positives = 56/123 (45%) Frame = -3 Query: 640 RDTSFVPSRALRGTIGYIAPEMISRSFGVISSKSDVYSFGMLLLEMAGGRRNADPNAANT 461 RD ++ + I + APE ++ + S+KSDV++FG+LL E+A + P A + Sbjct: 518 RDDTYTAHAGAKFPIKWTAPEGLA--YNKFSTKSDVWAFGVLLWEIATYGMSPYP-AIDL 574 Query: 460 SKAYYPSWVYDRLIQQDHVGEISTHVDVEMHELERKLCIVGLWCIQMKSNDRPTMSDTIE 281 + Y+ + + + E E+++L R+ C Q + DRPT Sbjct: 575 TDVYHK-------LDKGYRMERPPGCPPEVYDLMRQ-------CWQWDATDRPTFKSIHH 620 Query: 280 MLE 272 LE Sbjct: 621 ALE 623
>IRAK3_MOUSE (Q8K4B2) Interleukin-1 receptor-associated kinase 3 (EC 2.7.11.1)| (IRAK-3) (IL-1 receptor-associated kinase M) (IRAK-M) Length = 609 Score = 34.3 bits (77), Expect = 0.34 Identities = 32/130 (24%), Positives = 59/130 (45%), Gaps = 6/130 (4%) Frame = -3 Query: 607 RGTIGYIAPEMISRSFGVISSKSDVYSFGMLLLEMAGGRRNA--DPNAANTSKAYYPSWV 434 R + Y+ E I + G +S K+DVYSFG++++E+ G + DP + Sbjct: 348 RKHLWYMPEEYIRQ--GRLSVKTDVYSFGIVIMEVLTGCKVVLDDPKHVQLRD------L 399 Query: 433 YDRLIQQDHVGEISTHVDVEMHELER----KLCIVGLWCIQMKSNDRPTMSDTIEMLEGS 266 L+++ + + +D ++ R KL + C+ K+ RPTM + + LE + Sbjct: 400 LMELMEKRGLDSCLSFLDRKIPPCPRNFSAKLFSLAGRCVATKAKLRPTMDEVLSSLEST 459 Query: 265 VDALQMPSRP 236 +L P Sbjct: 460 QPSLYFAEDP 469
>SPKA_SYNY3 (Q9FAB3) Serine/threonine-protein kinase A (EC 2.7.11.1)| Length = 521 Score = 34.3 bits (77), Expect = 0.34 Identities = 16/49 (32%), Positives = 28/49 (57%) Frame = -3 Query: 619 SRALRGTIGYIAPEMISRSFGVISSKSDVYSFGMLLLEMAGGRRNADPN 473 ++A GT+ Y +PE + + S+SD+YS G+++ EM G P+ Sbjct: 185 TQAFMGTLAYCSPEQMEGK--ELDSRSDIYSLGVMMYEMLTGEMPLFPD 231
>IPL1_ASHGO (Q755C4) Spindle assembly checkpoint kinase (EC 2.7.11.1) (Aurora| kinase) Length = 367 Score = 34.3 bits (77), Expect = 0.34 Identities = 24/79 (30%), Positives = 41/79 (51%), Gaps = 1/79 (1%) Frame = -3 Query: 616 RALRGTIGYIAPEMI-SRSFGVISSKSDVYSFGMLLLEMAGGRRNADPNAANTSKAYYPS 440 + L GT+ Y++PE+I SR + + K DV++ G+L E+ G + P + + Y Sbjct: 264 KTLCGTVDYLSPELIRSREY---NEKVDVWALGVLTYELLVG---SPPFEEESKELTYKR 317 Query: 439 WVYDRLIQQDHVGEISTHV 383 + LI DHV + H+ Sbjct: 318 ILKRNLIFPDHVDTEARHL 336
>M3K10_HUMAN (Q02779) Mitogen-activated protein kinase kinase kinase 10 (EC| 2.7.11.25) (Mixed lineage kinase 2) (Protein kinase MST) Length = 954 Score = 33.9 bits (76), Expect = 0.44 Identities = 18/37 (48%), Positives = 25/37 (67%) Frame = -3 Query: 604 GTIGYIAPEMISRSFGVISSKSDVYSFGMLLLEMAGG 494 GT ++APE+I S + S SDV+SFG+LL E+ G Sbjct: 265 GTYAWMAPEVIRLS--LFSKSSDVWSFGVLLWELLTG 299
>MEK2_CAEEL (Q10664) Dual specificity mitogen-activated protein kinase kinase| mek-2 (EC 2.7.12.2) (MAP kinase kinase mek-2) Length = 387 Score = 33.9 bits (76), Expect = 0.44 Identities = 18/38 (47%), Positives = 26/38 (68%) Frame = -3 Query: 604 GTIGYIAPEMISRSFGVISSKSDVYSFGMLLLEMAGGR 491 GT Y+APE ++ S ISS D++SFG+ L+E+ GR Sbjct: 230 GTRSYMAPERLTGSHYTISS--DIWSFGLSLVELLIGR 265
>IRAK1_MOUSE (Q62406) Interleukin-1 receptor-associated kinase 1 (EC 2.7.11.1)| (IRAK-1) (IRAK) (Pelle-like protein kinase) (mPLK) Length = 710 Score = 33.9 bits (76), Expect = 0.44 Identities = 17/50 (34%), Positives = 28/50 (56%) Frame = -3 Query: 610 LRGTIGYIAPEMISRSFGVISSKSDVYSFGMLLLEMAGGRRNADPNAANT 461 +RGT+ Y+ E I G ++ +D +SFG+++LE G+R A T Sbjct: 384 VRGTLAYLPEEYIKT--GRLAVDTDTFSFGVVILETLAGQRAVRTQGAKT 431
>ABL1_MOUSE (P00520) Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2)| (p150) (c-ABL) (Abelson murine leukemia viral oncogene homolog 1) Length = 1123 Score = 33.9 bits (76), Expect = 0.44 Identities = 31/109 (28%), Positives = 53/109 (48%) Frame = -3 Query: 598 IGYIAPEMISRSFGVISSKSDVYSFGMLLLEMAGGRRNADPNAANTSKAYYPSWVYDRLI 419 I + APE S ++ S KSDV++FG+LL E+A + P + S+ Y L+ Sbjct: 403 IKWTAPE--SLAYNKFSIKSDVWAFGVLLWEIATYGMSPYP-GIDLSQVY-------ELL 452 Query: 418 QQDHVGEISTHVDVEMHELERKLCIVGLWCIQMKSNDRPTMSDTIEMLE 272 ++D+ E +++EL R C Q +DRP+ ++ + E Sbjct: 453 EKDYRMERPEGCPEKVYELMRA-------CWQWNPSDRPSFAEIHQAFE 494
>ABL1_HUMAN (P00519) Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2)| (p150) (c-ABL) (Abelson murine leukemia viral oncogene homolog 1) Length = 1130 Score = 33.9 bits (76), Expect = 0.44 Identities = 31/109 (28%), Positives = 53/109 (48%) Frame = -3 Query: 598 IGYIAPEMISRSFGVISSKSDVYSFGMLLLEMAGGRRNADPNAANTSKAYYPSWVYDRLI 419 I + APE S ++ S KSDV++FG+LL E+A + P + S+ Y L+ Sbjct: 403 IKWTAPE--SLAYNKFSIKSDVWAFGVLLWEIATYGMSPYP-GIDLSQVY-------ELL 452 Query: 418 QQDHVGEISTHVDVEMHELERKLCIVGLWCIQMKSNDRPTMSDTIEMLE 272 ++D+ E +++EL R C Q +DRP+ ++ + E Sbjct: 453 EKDYRMERPEGCPEKVYELMRA-------CWQWNPSDRPSFAEIHQAFE 494
>PKPA_PHYBL (Q01577) Serine/threonine-protein kinase pkpA (EC 2.7.11.1)| Length = 613 Score = 33.9 bits (76), Expect = 0.44 Identities = 18/37 (48%), Positives = 23/37 (62%) Frame = -3 Query: 604 GTIGYIAPEMISRSFGVISSKSDVYSFGMLLLEMAGG 494 GT ++APEM + K D+Y+FGM LLEMA G Sbjct: 175 GTPEFMAPEMYEEQG--YNEKVDIYAFGMCLLEMATG 209
>M3K6_HUMAN (O95382) Mitogen-activated protein kinase kinase kinase 6 (EC| 2.7.11.25) Length = 1011 Score = 33.9 bits (76), Expect = 0.44 Identities = 15/38 (39%), Positives = 24/38 (63%) Frame = -3 Query: 604 GTIGYIAPEMISRSFGVISSKSDVYSFGMLLLEMAGGR 491 GT+ Y+APE+I + +D++S G ++EMA GR Sbjct: 532 GTLQYMAPEIIDQGPRGYGKAADIWSLGCTVIEMATGR 569
>ABL_MLVAB (P00521) Tyrosine-protein kinase transforming protein Abl (EC| 2.7.10.2) (V-abl) Length = 746 Score = 33.9 bits (76), Expect = 0.44 Identities = 31/109 (28%), Positives = 53/109 (48%) Frame = -3 Query: 598 IGYIAPEMISRSFGVISSKSDVYSFGMLLLEMAGGRRNADPNAANTSKAYYPSWVYDRLI 419 I + APE S ++ S KSDV++FG+LL E+A + P + S+ Y L+ Sbjct: 289 IKWTAPE--SLAYNKFSIKSDVWAFGVLLWEIATYGMSPYP-GIDLSQVY-------ELL 338 Query: 418 QQDHVGEISTHVDVEMHELERKLCIVGLWCIQMKSNDRPTMSDTIEMLE 272 ++D+ E +++EL R C Q +DRP+ ++ + E Sbjct: 339 EKDYRMERPEGCPEKVYELMRA-------CWQWNPSDRPSFAEIHQAFE 380
>SRMS_HUMAN (Q9H3Y6) Tyrosine-protein kinase Srms (EC 2.7.10.2)| Length = 488 Score = 33.9 bits (76), Expect = 0.44 Identities = 18/46 (39%), Positives = 30/46 (65%) Frame = -3 Query: 640 RDTSFVPSRALRGTIGYIAPEMISRSFGVISSKSDVYSFGMLLLEM 503 +D + PS + + + + APE + ++ V S KSDV+SFG+LL E+ Sbjct: 376 KDDIYSPSSSSKIPVKWTAPE--AANYRVFSQKSDVWSFGVLLHEV 419
>LCK_CHICK (P42683) Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2)| (Protein-tyrosine kinase C-TKL) (p56tk1) Length = 507 Score = 33.9 bits (76), Expect = 0.44 Identities = 20/58 (34%), Positives = 29/58 (50%) Frame = -3 Query: 637 DTSFVPSRALRGTIGYIAPEMISRSFGVISSKSDVYSFGMLLLEMAGGRRNADPNAAN 464 D + + I + APE I+ +G + KSDV+SFG+LL E+ R P N Sbjct: 389 DNEYTAREGAKFPIKWTAPEAIN--YGTFTIKSDVWSFGILLTEIVTYGRIPYPGMTN 444
>FGR_MOUSE (P14234) Proto-oncogene tyrosine-protein kinase FGR (EC 2.7.10.2)| (P55-FGR) (C-FGR) Length = 517 Score = 33.9 bits (76), Expect = 0.44 Identities = 21/58 (36%), Positives = 30/58 (51%) Frame = -3 Query: 637 DTSFVPSRALRGTIGYIAPEMISRSFGVISSKSDVYSFGMLLLEMAGGRRNADPNAAN 464 D + P + + I + APE + FG + KSDV+SFG+LL E+ R P N Sbjct: 397 DNEYNPQQGTKFPIKWTAPE--AALFGRFTVKSDVWSFGILLTELITKGRVPYPGMNN 452
>M3K11_HUMAN (Q16584) Mitogen-activated protein kinase kinase kinase 11 (EC| 2.7.11.25) (Mixed lineage kinase 3) (Src-homology 3 domain-containing proline-rich kinase) Length = 847 Score = 33.5 bits (75), Expect = 0.57 Identities = 18/37 (48%), Positives = 24/37 (64%) Frame = -3 Query: 604 GTIGYIAPEMISRSFGVISSKSDVYSFGMLLLEMAGG 494 GT ++APE+I S S SDV+SFG+LL E+ G Sbjct: 284 GTYAWMAPEVIKAS--TFSKGSDVWSFGVLLWELLTG 318
>PGFRB_MOUSE (P05622) Beta platelet-derived growth factor receptor precursor (EC| 2.7.10.1) (PDGF-R-beta) Length = 1098 Score = 33.5 bits (75), Expect = 0.57 Identities = 31/123 (25%), Positives = 55/123 (44%) Frame = -3 Query: 640 RDTSFVPSRALRGTIGYIAPEMISRSFGVISSKSDVYSFGMLLLEMAGGRRNADPNAANT 461 RD++++ + + ++APE I S + ++ SDV+SFG+LL E+ P Sbjct: 852 RDSNYISKGSTYLPLKWMAPESIFNS--LYTTLSDVWSFGILLWEIFTLGGTPYPELPMN 909 Query: 460 SKAYYPSWVYDRLIQQDHVGEISTHVDVEMHELERKLCIVGLWCIQMKSNDRPTMSDTIE 281 + Y R+ Q H + E++E+ +K C + K RP S + Sbjct: 910 DQFYNAIKRGYRMAQPAHASD-------EIYEIMQK-------CWEEKFETRPPFSQLVL 955 Query: 280 MLE 272 +LE Sbjct: 956 LLE 958
>M3K5_MOUSE (O35099) Mitogen-activated protein kinase kinase kinase 5 (EC| 2.7.11.25) (MAPK/ERK kinase kinase 5) (MEK kinase 5) (MEKK 5) (Apoptosis signal-regulating kinase 1) (ASK-1) Length = 1380 Score = 33.5 bits (75), Expect = 0.57 Identities = 14/38 (36%), Positives = 24/38 (63%) Frame = -3 Query: 604 GTIGYIAPEMISRSFGVISSKSDVYSFGMLLLEMAGGR 491 GT+ Y+APE+I + +D++S G ++EMA G+ Sbjct: 848 GTLQYMAPEIIDKGPRGYGKAADIWSLGCTIIEMATGK 885
>KYK1_DICDI (P18160) Non-receptor tyrosine kinase spore lysis A (EC 2.7.10.2)| (Tyrosine-protein kinase 1) Length = 1584 Score = 33.5 bits (75), Expect = 0.57 Identities = 17/34 (50%), Positives = 22/34 (64%) Frame = -3 Query: 604 GTIGYIAPEMISRSFGVISSKSDVYSFGMLLLEM 503 G I Y+APE+ S KSDVYS+GM+L E+ Sbjct: 1467 GCIPYMAPEVFKGDSN--SEKSDVYSYGMVLFEL 1498
>PTK6_HUMAN (Q13882) Tyrosine-protein kinase 6 (EC 2.7.10.2) (Breast tumor| kinase) (Tyrosine-protein kinase BRK) Length = 451 Score = 33.5 bits (75), Expect = 0.57 Identities = 20/43 (46%), Positives = 27/43 (62%) Frame = -3 Query: 592 YIAPEMISRSFGVISSKSDVYSFGMLLLEMAGGRRNADPNAAN 464 + APE +SR G S+KSDV+SFG+LL EM + P +N Sbjct: 353 WTAPEALSR--GHYSTKSDVWSFGILLHEMFSRGQVPYPGMSN 393
>M3K5_HUMAN (Q99683) Mitogen-activated protein kinase kinase kinase 5 (EC| 2.7.11.25) (MAPK/ERK kinase kinase 5) (MEK kinase 5) (MEKK 5) (Apoptosis signal-regulating kinase 1) (ASK-1) Length = 1374 Score = 33.5 bits (75), Expect = 0.57 Identities = 14/38 (36%), Positives = 24/38 (63%) Frame = -3 Query: 604 GTIGYIAPEMISRSFGVISSKSDVYSFGMLLLEMAGGR 491 GT+ Y+APE+I + +D++S G ++EMA G+ Sbjct: 841 GTLQYMAPEIIDKGPRGYGKAADIWSLGCTIIEMATGK 878
>LRRK2_HUMAN (Q5S007) Leucine-rich repeat serine/threonine-protein kinase 2 (EC| 2.7.11.1) (Dardarin) Length = 2527 Score = 33.5 bits (75), Expect = 0.57 Identities = 18/40 (45%), Positives = 28/40 (70%), Gaps = 2/40 (5%) Frame = -3 Query: 604 GTIGYIAPEMISRSFGVISSKSDVYSFGMLLLEM--AGGR 491 GT G+ APE ++R + + ++DVYSFG+LL ++ GGR Sbjct: 2034 GTPGFRAPE-VARGNVIYNQQADVYSFGLLLYDILTTGGR 2072
>GPRK2_DROME (P32866) G protein-coupled receptor kinase 2 (EC 2.7.11.16)| Length = 714 Score = 33.5 bits (75), Expect = 0.57 Identities = 18/38 (47%), Positives = 23/38 (60%) Frame = -3 Query: 604 GTIGYIAPEMISRSFGVISSKSDVYSFGMLLLEMAGGR 491 GT+GY+APE+I S D +SFG LL EM G+ Sbjct: 471 GTVGYMAPEVIDNEKYAFS--PDWFSFGCLLYEMIEGQ 506
>CPK15_ARATH (P92937) CBL-interacting serine/threonine-protein kinase 15 (EC| 2.7.11.1) (Serine/threonine-protein kinase ATPK10) (SOS2-like protein kinase PKS3) (SOS-interacting protein 2) (SNF1-related kinase 3.1) Length = 421 Score = 33.5 bits (75), Expect = 0.57 Identities = 17/37 (45%), Positives = 25/37 (67%) Frame = -3 Query: 604 GTIGYIAPEMISRSFGVISSKSDVYSFGMLLLEMAGG 494 GT Y+APE+ISR+ G K+DV+S G++L + G Sbjct: 173 GTPAYVAPEVISRN-GYDGFKADVWSCGVILFVLLAG 208
>KIT_HUMAN (P10721) Mast/stem cell growth factor receptor precursor (EC| 2.7.10.1) (SCFR) (Proto-oncogene tyrosine-protein kinase Kit) (c-kit) (CD117 antigen) Length = 976 Score = 33.5 bits (75), Expect = 0.57 Identities = 35/167 (20%), Positives = 65/167 (38%) Frame = -3 Query: 637 DTSFVPSRALRGTIGYIAPEMISRSFGVISSKSDVYSFGMLLLEMAGGRRNADPNAANTS 458 D+++V R + ++APE I V + +SDV+S+G+ L E+ + P S Sbjct: 820 DSNYVVKGNARLPVKWMAPESIFNC--VYTFESDVWSYGIFLWELFSLGSSPYPGMPVDS 877 Query: 457 KAYYPSWVYDRLIQQDHVGEISTHVDVEMHELERKLCIVGLWCIQMKSNDRPTMSDTIEM 278 K Y ++I++ H EM+++ + C RPT +++ Sbjct: 878 KFY-------KMIKEGFRMLSPEHAPAEMYDIMKT-------CWDADPLKRPTFKQIVQL 923 Query: 277 LEGSVDALQMPSRPFFCDEGHVQTEDTYHLTSELTEISKEDMRENID 137 +E + +E T H+ S L S + +D Sbjct: 924 IEKQI------------------SESTNHIYSNLANCSPNRQKPVVD 952
>FGR_HUMAN (P09769) Proto-oncogene tyrosine-protein kinase FGR (EC 2.7.10.2)| (P55-FGR) (C-FGR) Length = 529 Score = 33.1 bits (74), Expect = 0.75 Identities = 18/46 (39%), Positives = 28/46 (60%) Frame = -3 Query: 640 RDTSFVPSRALRGTIGYIAPEMISRSFGVISSKSDVYSFGMLLLEM 503 +D + P + + I + APE + FG + KSDV+SFG+LL E+ Sbjct: 408 KDDEYNPCQGSKFPIKWTAPE--AALFGRFTIKSDVWSFGILLTEL 451
>INSR_DROME (P09208) Insulin-like receptor precursor (EC 2.7.10.1) (DIR) (DInr)| (dIRH) [Contains: Insulin-like receptor alpha subunit; Insulin-like receptor beta 1 subunit; Insulin-like receptor beta 2 subunit] Length = 2144 Score = 33.1 bits (74), Expect = 0.75 Identities = 32/117 (27%), Positives = 47/117 (40%) Frame = -3 Query: 559 GVISSKSDVYSFGMLLLEMAGGRRNADPNAANTSKAYYPSWVYDRLIQQDHVGEISTHVD 380 GV SS SDV+SFG++L EMA +N Y + V E + Sbjct: 1571 GVYSSASDVFSFGVVLWEMATLAAQPYQGLSNEQVLRY--------VIDGGVMERPENCP 1622 Query: 379 VEMHELERKLCIVGLWCIQMKSNDRPTMSDTIEMLEGSVDALQMPSRPFFCDEGHVQ 209 +H+L ++ C +S+ RP+ D I LE Q F+ E +Q Sbjct: 1623 DFLHKLMQR-------CWHHRSSARPSFLDIIAYLEPQCPNSQFKEVSFYHSEAGLQ 1672
>WNK3_HUMAN (Q9BYP7) Serine/threonine-protein kinase WNK3 (EC 2.7.11.1)| (Protein kinase with no lysine 3) (Protein kinase, lysine-deficient 3) Length = 1743 Score = 33.1 bits (74), Expect = 0.75 Identities = 19/45 (42%), Positives = 28/45 (62%) Frame = -3 Query: 634 TSFVPSRALRGTIGYIAPEMISRSFGVISSKSDVYSFGMLLLEMA 500 TSF ++++ GT ++APEM + DVY+FGM +LEMA Sbjct: 303 TSF--AKSVIGTPEFMAPEMYEEHY---DESVDVYAFGMCMLEMA 342
>M3LK7_DROME (P83104) Putative mitogen-activated protein kinase kinase kinase| 7-like (EC 2.7.11.25) Length = 393 Score = 33.1 bits (74), Expect = 0.75 Identities = 16/36 (44%), Positives = 25/36 (69%) Frame = -3 Query: 610 LRGTIGYIAPEMISRSFGVISSKSDVYSFGMLLLEM 503 ++GT+ Y+APE I ++K DVYSFG++L E+ Sbjct: 166 MQGTLRYMAPEAIKHL--KYTAKCDVYSFGIMLWEL 199
>KOIA_SCHPO (Q9Y7J6) Putative serine/threonine-protein kinase C1778.10c (EC| 2.7.11.1) Length = 550 Score = 33.1 bits (74), Expect = 0.75 Identities = 15/37 (40%), Positives = 25/37 (67%) Frame = -3 Query: 604 GTIGYIAPEMISRSFGVISSKSDVYSFGMLLLEMAGG 494 GT Y+APE++SR V+S SD+++F ++ +M G Sbjct: 222 GTAEYVAPELLSRQ--VVSKSSDLWAFACVVYQMIVG 256
>YES_XIPHE (P27447) Tyrosine-protein kinase Yes (EC 2.7.10.2) (p61-Yes)| Length = 543 Score = 33.1 bits (74), Expect = 0.75 Identities = 32/137 (23%), Positives = 55/137 (40%), Gaps = 3/137 (2%) Frame = -3 Query: 637 DTSFVPSRALRGTIGYIAPEMISRSFGVISSKSDVYSFGMLLLEMAGGRRNADPNAANTS 458 D + + + I + APE + +G + KSDV+SFG+LL E+ Sbjct: 423 DNEYTARQGAKFPIKWTAPE--AALYGRFTIKSDVWSFGILLTEL-----------VTKG 469 Query: 457 KAYYPSWVYDRLIQQDHVG---EISTHVDVEMHELERKLCIVGLWCIQMKSNDRPTMSDT 287 + YP V +++Q G +HE+ R+ C + + ++RPT Sbjct: 470 RVPYPGMVNREVLEQVDRGYRMPCPQGCPESLHEMMRQ-------CWKKEPDERPTFEYI 522 Query: 286 IEMLEGSVDALQMPSRP 236 LE A + +P Sbjct: 523 QSFLEDYFTATEPQYQP 539
>PGFRB_RAT (Q05030) Beta platelet-derived growth factor receptor precursor (EC| 2.7.10.1) (PDGF-R-beta) Length = 1097 Score = 33.1 bits (74), Expect = 0.75 Identities = 31/123 (25%), Positives = 55/123 (44%) Frame = -3 Query: 640 RDTSFVPSRALRGTIGYIAPEMISRSFGVISSKSDVYSFGMLLLEMAGGRRNADPNAANT 461 RD++++ + + ++APE I S + ++ SDV+SFG+LL E+ P Sbjct: 852 RDSNYISKGSTFLPLKWMAPESIFNS--LYTTLSDVWSFGILLWEIFTLGGTPYPELPMN 909 Query: 460 SKAYYPSWVYDRLIQQDHVGEISTHVDVEMHELERKLCIVGLWCIQMKSNDRPTMSDTIE 281 + Y R+ Q H + E++E+ +K C + K RP S + Sbjct: 910 DQFYNAIKRGYRMAQPAHASD-------EIYEIMQK-------CWEEKFETRPPFSQLVL 955 Query: 280 MLE 272 +LE Sbjct: 956 LLE 958
>KIT_CANFA (O97799) Mast/stem cell growth factor receptor precursor (EC| 2.7.10.1) (SCFR) (Proto-oncogene tyrosine-protein kinase Kit) (c-kit) Length = 975 Score = 33.1 bits (74), Expect = 0.75 Identities = 35/167 (20%), Positives = 65/167 (38%) Frame = -3 Query: 637 DTSFVPSRALRGTIGYIAPEMISRSFGVISSKSDVYSFGMLLLEMAGGRRNADPNAANTS 458 D+++V R + ++APE I V + +SDV+S+G+ L E+ + P S Sbjct: 819 DSNYVVKGNARLPVKWMAPESIFNC--VYTFESDVWSYGIFLWELFSLGSSPYPGMPVDS 876 Query: 457 KAYYPSWVYDRLIQQDHVGEISTHVDVEMHELERKLCIVGLWCIQMKSNDRPTMSDTIEM 278 K Y ++I++ H EM+++ + C RPT +++ Sbjct: 877 KFY-------KMIKEGFRMLSPEHAPAEMYDIMKT-------CWDADPLKRPTFKQIVQL 922 Query: 277 LEGSVDALQMPSRPFFCDEGHVQTEDTYHLTSELTEISKEDMRENID 137 +E + ++ T H+ S L S R +D Sbjct: 923 IEKQI------------------SDSTNHIYSNLANCSPNPERPVVD 951
>TTK_HUMAN (P33981) Dual specificity protein kinase TTK (EC 2.7.12.1)| (Phosphotyrosine picked threonine-protein kinase) (PYT) Length = 841 Score = 32.7 bits (73), Expect = 0.98 Identities = 21/58 (36%), Positives = 29/58 (50%), Gaps = 9/58 (15%) Frame = -3 Query: 637 DTSFVPSRALRGTIGYIAPEMI---------SRSFGVISSKSDVYSFGMLLLEMAGGR 491 DT+ V + GT+ Y+ PE I +S IS KSDV+S G +L M G+ Sbjct: 658 DTTSVVKDSQVGTVNYMPPEAIKDMSSSRENGKSKSKISPKSDVWSLGCILYYMTYGK 715
>BRAF1_COTJA (P34908) B-Raf proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (RMIL serine/threonine-protein kinase) (c-RMIL) Length = 807 Score = 32.7 bits (73), Expect = 0.98 Identities = 35/141 (24%), Positives = 63/141 (44%), Gaps = 4/141 (2%) Frame = -3 Query: 610 LRGTIGYIAPEMIS-RSFGVISSKSDVYSFGMLLLEMAGGRRNADPNAANTSKAYYPSWV 434 L G+I ++APE+I + S +SDVY+FG++L E+ G+ N N Sbjct: 653 LSGSILWMAPEVIRMQDKNPYSFQSDVYAFGIVLYELMTGQLPYS-NINNR--------- 702 Query: 433 YDRLIQQDHVGEISTHVDVEMHELERKLCIVGLWCIQMKSNDRPTMSD---TIEMLEGSV 263 D++I G +S + + + + C++ K ++RP +IE+L S+ Sbjct: 703 -DQIIFMVGRGYLSPDLSKVRSNCPKAMKRLMAECLKKKRDERPLFPQILASIELLARSL 761 Query: 262 DALQMPSRPFFCDEGHVQTED 200 + + + QTED Sbjct: 762 PKIHRSASEPSLNRAGFQTED 782
>MKK2_YEAST (P32491) MAP kinase kinase MKK2/SSP33 (EC 2.7.12.2)| Length = 506 Score = 32.7 bits (73), Expect = 0.98 Identities = 19/38 (50%), Positives = 23/38 (60%) Frame = -3 Query: 604 GTIGYIAPEMISRSFGVISSKSDVYSFGMLLLEMAGGR 491 GT Y+APE I S DV+S G+ LLE+AGGR Sbjct: 377 GTSFYMAPERIQGQ--PYSVTCDVWSLGLTLLEVAGGR 412
>ABL1_CAEEL (P03949) Tyrosine-protein kinase abl-1 (EC 2.7.10.2)| Length = 1224 Score = 32.7 bits (73), Expect = 0.98 Identities = 17/49 (34%), Positives = 30/49 (61%) Frame = -3 Query: 646 YPRDTSFVPSRALRGTIGYIAPEMISRSFGVISSKSDVYSFGMLLLEMA 500 + ++ ++ + I + APE ++ F SSKSDV++FG+LL E+A Sbjct: 456 FMKEDTYTAHAGAKFPIKWTAPEGLA--FNTFSSKSDVWAFGVLLWEIA 502
>ABL_FSVHY (P10447) Tyrosine-protein kinase transforming protein Abl (EC| 2.7.10.2) (V-abl) Length = 439 Score = 32.7 bits (73), Expect = 0.98 Identities = 30/103 (29%), Positives = 50/103 (48%) Frame = -3 Query: 598 IGYIAPEMISRSFGVISSKSDVYSFGMLLLEMAGGRRNADPNAANTSKAYYPSWVYDRLI 419 I + APE S ++ S KSDV++FG+LL E+A + P + S+ Y L+ Sbjct: 352 IKWTAPE--SLAYNKFSIKSDVWAFGVLLWEIATYGMSPYP-GIDLSQVY-------ELL 401 Query: 418 QQDHVGEISTHVDVEMHELERKLCIVGLWCIQMKSNDRPTMSD 290 ++D+ E +++EL R C Q +DRP ++ Sbjct: 402 EKDYRMERPEGCPEKVYELMRA-------CWQWNPSDRPAFAE 437
>BRAF1_CHICK (Q04982) B-Raf proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (Rmil serine/threonine-protein kinase) (c-Rmil) Length = 806 Score = 32.7 bits (73), Expect = 0.98 Identities = 35/141 (24%), Positives = 63/141 (44%), Gaps = 4/141 (2%) Frame = -3 Query: 610 LRGTIGYIAPEMIS-RSFGVISSKSDVYSFGMLLLEMAGGRRNADPNAANTSKAYYPSWV 434 L G+I ++APE+I + S +SDVY+FG++L E+ G+ N N Sbjct: 653 LSGSILWMAPEVIRMQDKNPYSFQSDVYAFGIVLYELMTGQLPYS-NINNR--------- 702 Query: 433 YDRLIQQDHVGEISTHVDVEMHELERKLCIVGLWCIQMKSNDRPTMSD---TIEMLEGSV 263 D++I G +S + + + + C++ K ++RP +IE+L S+ Sbjct: 703 -DQIIFMVGRGYLSPDLSKVRSNCPKAMKRLMAECLKKKRDERPLFPQILASIELLARSL 761 Query: 262 DALQMPSRPFFCDEGHVQTED 200 + + + QTED Sbjct: 762 PKIHRSASEPSLNRAGFQTED 782
>WNK1_HUMAN (Q9H4A3) Serine/threonine-protein kinase WNK1 (EC 2.7.11.1)| (Protein kinase with no lysine 1) (Protein kinase, lysine-deficient 1) (Kinase deficient protein) Length = 2382 Score = 32.7 bits (73), Expect = 0.98 Identities = 16/40 (40%), Positives = 25/40 (62%) Frame = -3 Query: 619 SRALRGTIGYIAPEMISRSFGVISSKSDVYSFGMLLLEMA 500 ++++ GT ++APEM + DVY+FGM +LEMA Sbjct: 380 AKSVIGTPEFMAPEMYEEKY---DESVDVYAFGMCMLEMA 416
>WNK1_MOUSE (P83741) Serine/threonine-protein kinase WNK1 (EC 2.7.11.1)| (Protein kinase with no lysine 1) (Protein kinase, lysine-deficient 1) Length = 2377 Score = 32.7 bits (73), Expect = 0.98 Identities = 16/40 (40%), Positives = 25/40 (62%) Frame = -3 Query: 619 SRALRGTIGYIAPEMISRSFGVISSKSDVYSFGMLLLEMA 500 ++++ GT ++APEM + DVY+FGM +LEMA Sbjct: 380 AKSVIGTPEFMAPEMYEEKY---DESVDVYAFGMCMLEMA 416
>RMIL_AVEVR (P27966) Serine/threonine-protein kinase transforming protein Rmil| (EC 2.7.11.1) Length = 450 Score = 32.7 bits (73), Expect = 0.98 Identities = 35/141 (24%), Positives = 63/141 (44%), Gaps = 4/141 (2%) Frame = -3 Query: 610 LRGTIGYIAPEMIS-RSFGVISSKSDVYSFGMLLLEMAGGRRNADPNAANTSKAYYPSWV 434 L G+I ++APE+I + S +SDVY+FG++L E+ G+ N N Sbjct: 239 LSGSILWMAPEVIRMQDKNPYSFQSDVYAFGIVLYELMTGQLPYS-NINNR--------- 288 Query: 433 YDRLIQQDHVGEISTHVDVEMHELERKLCIVGLWCIQMKSNDRPTMSD---TIEMLEGSV 263 D++I G +S + + + + C++ K ++RP +IE+L S+ Sbjct: 289 -DQIIFMVGRGYLSPDLSKVRSNCPKAMKRLMAECLKKKRDERPLFPQILASIELLARSL 347 Query: 262 DALQMPSRPFFCDEGHVQTED 200 + + + QTED Sbjct: 348 PKIHRSASEPSLNRAGFQTED 368
>TOPK_HUMAN (Q96KB5) T-lymphokine-activated killer cell-originated protein| kinase (EC 2.7.12.2) (T-LAK cell-originated protein kinase) (PDZ-binding kinase) (Spermatogenesis-related protein kinase) (SPK) (MAPKK-like protein kinase) (Nori-3) Length = 322 Score = 32.7 bits (73), Expect = 0.98 Identities = 31/126 (24%), Positives = 55/126 (43%), Gaps = 6/126 (4%) Frame = -3 Query: 622 PSRALRGTIGYIAPEMISRSFGVISSKSDVYSFGMLLLEM---AGGRRNADPNAANTSKA 452 P GT + E + + GVI+ K+D+++FG+ L EM + N + + K Sbjct: 202 PEACYIGTEPWKPKEAVEEN-GVITDKADIFAFGLTLWEMMTLSIPHINLSNDDDDEDKT 260 Query: 451 YYPSWVYDRLIQQDHVGEISTHVDVEMHELE---RKLCIVGLWCIQMKSNDRPTMSDTIE 281 + S D + + + T + M EL+ +K+ + C DRP+ + +E Sbjct: 261 FDESDFDD----EAYYAALGTRPPINMEELDESYQKVIELFSVCTNEDPKDRPSAAHIVE 316 Query: 280 MLEGSV 263 LE V Sbjct: 317 ALETDV 322
>YES_XENLA (P10936) Tyrosine-protein kinase Yes (EC 2.7.10.2) (p61-Yes)| Length = 536 Score = 32.7 bits (73), Expect = 0.98 Identities = 35/137 (25%), Positives = 55/137 (40%), Gaps = 3/137 (2%) Frame = -3 Query: 637 DTSFVPSRALRGTIGYIAPEMISRSFGVISSKSDVYSFGMLLLEMAGGRRNADPNAANTS 458 D + + + I + APE + +G + KSDV+SFG+LL E+ Sbjct: 416 DNEYTARQGAKFPIKWTAPE--AALYGRFTIKSDVWSFGILLTELVA-----------KG 462 Query: 457 KAYYPSWVYDRLIQQDHVG---EISTHVDVEMHELERKLCIVGLWCIQMKSNDRPTMSDT 287 + YP V +++Q G +HEL KLC W + ++RPT Sbjct: 463 RVPYPGMVNREVLEQVERGYRMPCPQRCPESLHEL-MKLC----W--KKDPDERPTFEYI 515 Query: 286 IEMLEGSVDALQMPSRP 236 LE A + +P Sbjct: 516 QSFLEDYFTATEPQYQP 532
>ST32A_HUMAN (Q8WU08) Serine/threonine-protein kinase 32A (EC 2.7.11.1) (YANK1)| Length = 396 Score = 32.7 bits (73), Expect = 0.98 Identities = 23/68 (33%), Positives = 33/68 (48%), Gaps = 1/68 (1%) Frame = -3 Query: 655 AKLYPRDTSFVPSRALRGTIGYIAPEMISRSFGV-ISSKSDVYSFGMLLLEMAGGRRNAD 479 A + PR+T + GT Y+APEM S G S D +S G+ E+ GRR Sbjct: 168 AAMLPRETQIT---TMAGTKPYMAPEMFSSRKGAGYSFAVDWWSLGVTAYELLRGRRPYH 224 Query: 478 PNAANTSK 455 ++ +SK Sbjct: 225 IRSSTSSK 232
>BRAF1_HUMAN (P15056) B-Raf proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (p94) (v-Raf murine sarcoma viral oncogene homolog B1) Length = 766 Score = 32.7 bits (73), Expect = 0.98 Identities = 35/141 (24%), Positives = 63/141 (44%), Gaps = 4/141 (2%) Frame = -3 Query: 610 LRGTIGYIAPEMIS-RSFGVISSKSDVYSFGMLLLEMAGGRRNADPNAANTSKAYYPSWV 434 L G+I ++APE+I + S +SDVY+FG++L E+ G+ N N Sbjct: 613 LSGSILWMAPEVIRMQDKNPYSFQSDVYAFGIVLYELMTGQLPYS-NINNR--------- 662 Query: 433 YDRLIQQDHVGEISTHVDVEMHELERKLCIVGLWCIQMKSNDRPTMSD---TIEMLEGSV 263 D++I G +S + + + + C++ K ++RP +IE+L S+ Sbjct: 663 -DQIIFMVGRGYLSPDLSKVRSNCPKAMKRLMAECLKKKRDERPLFPQILASIELLARSL 721 Query: 262 DALQMPSRPFFCDEGHVQTED 200 + + + QTED Sbjct: 722 PKIHRSASEPSLNRAGFQTED 742
>KIT_CAPHI (Q28317) Mast/stem cell growth factor receptor precursor (EC| 2.7.10.1) (SCFR) (Proto-oncogene tyrosine-protein kinase Kit) (c-kit) Length = 978 Score = 32.7 bits (73), Expect = 0.98 Identities = 37/165 (22%), Positives = 65/165 (39%) Frame = -3 Query: 637 DTSFVPSRALRGTIGYIAPEMISRSFGVISSKSDVYSFGMLLLEMAGGRRNADPNAANTS 458 D+++V R + ++APE I V + +SDV+S+G+ L E+ + P S Sbjct: 822 DSNYVVKGNARLPVKWMAPESIFNC--VYTFESDVWSYGIFLWELFSLGSSPYPGMPVDS 879 Query: 457 KAYYPSWVYDRLIQQDHVGEISTHVDVEMHELERKLCIVGLWCIQMKSNDRPTMSDTIEM 278 K Y ++I++ H EM+++ + C RPT +++ Sbjct: 880 KFY-------KMIKEGFRMLSPEHAPAEMYDIMKT-------CWDADPLKRPTFKQIVQL 925 Query: 277 LEGSVDALQMPSRPFFCDEGHVQTEDTYHLTSELTEISKEDMREN 143 +E + +E T H+ S L S REN Sbjct: 926 IEKQI------------------SESTNHIYSNLANCSPH--REN 950
>KIT_BOVIN (P43481) Mast/stem cell growth factor receptor precursor (EC| 2.7.10.1) (SCFR) (Proto-oncogene tyrosine-protein kinase Kit) (c-kit) Length = 977 Score = 32.7 bits (73), Expect = 0.98 Identities = 37/165 (22%), Positives = 65/165 (39%) Frame = -3 Query: 637 DTSFVPSRALRGTIGYIAPEMISRSFGVISSKSDVYSFGMLLLEMAGGRRNADPNAANTS 458 D+++V R + ++APE I V + +SDV+S+G+ L E+ + P S Sbjct: 821 DSNYVVKGNARLPVKWMAPESIFNC--VYTFESDVWSYGIFLWELFSLGSSPYPGMPVDS 878 Query: 457 KAYYPSWVYDRLIQQDHVGEISTHVDVEMHELERKLCIVGLWCIQMKSNDRPTMSDTIEM 278 K Y ++I++ H EM+++ + C RPT +++ Sbjct: 879 KFY-------KMIKEGFRMLSPEHAPAEMYDIMKT-------CWDADPLKRPTFKQIVQL 924 Query: 277 LEGSVDALQMPSRPFFCDEGHVQTEDTYHLTSELTEISKEDMREN 143 +E + +E T H+ S L S REN Sbjct: 925 IEKQI------------------SESTNHIYSNLANCSPH--REN 949
>WNK1_RAT (Q9JIH7) Serine/threonine-protein kinase WNK1 (EC 2.7.11.1)| (Protein kinase with no lysine 1) (Protein kinase, lysine-deficient 1) Length = 2126 Score = 32.7 bits (73), Expect = 0.98 Identities = 16/40 (40%), Positives = 25/40 (62%) Frame = -3 Query: 619 SRALRGTIGYIAPEMISRSFGVISSKSDVYSFGMLLLEMA 500 ++++ GT ++APEM + DVY+FGM +LEMA Sbjct: 380 AKSVIGTPEFMAPEMYEEKY---DESVDVYAFGMCMLEMA 416
>PMYT1_XENLA (Q91618) Membrane-associated tyrosine- and threonine-specific| cdc2-inhibitory kinase (EC 2.7.11.1) (Myt1 kinase) Length = 548 Score = 32.7 bits (73), Expect = 0.98 Identities = 17/38 (44%), Positives = 24/38 (63%) Frame = -3 Query: 613 ALRGTIGYIAPEMISRSFGVISSKSDVYSFGMLLLEMA 500 A G Y+APE++ G+ S +DV+S GM LLE+A Sbjct: 260 AQEGDPRYMAPELLD---GIFSKAADVFSLGMSLLEVA 294
>BRAF1_MOUSE (P28028) B-Raf proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (Fragment) Length = 328 Score = 32.7 bits (73), Expect = 0.98 Identities = 35/141 (24%), Positives = 63/141 (44%), Gaps = 4/141 (2%) Frame = -3 Query: 610 LRGTIGYIAPEMIS-RSFGVISSKSDVYSFGMLLLEMAGGRRNADPNAANTSKAYYPSWV 434 L G+I ++APE+I + S +SDVY+FG++L E+ G+ N N Sbjct: 175 LSGSILWMAPEVIRMQDKNPYSFQSDVYAFGIVLYELMTGQLPYS-NINNR--------- 224 Query: 433 YDRLIQQDHVGEISTHVDVEMHELERKLCIVGLWCIQMKSNDRPTMSD---TIEMLEGSV 263 D++I G +S + + + + C++ K ++RP +IE+L S+ Sbjct: 225 -DQIIFMVGRGYLSPDLSKVRSNCPKAMKRLMAECLKKKRDERPLFPQILASIELLARSL 283 Query: 262 DALQMPSRPFFCDEGHVQTED 200 + + + QTED Sbjct: 284 PKIHRSASEPSLNRAGFQTED 304
>RMIL_AVII1 (P10533) Serine/threonine-protein kinase transforming protein Rmil| (EC 2.7.11.1) Length = 367 Score = 32.7 bits (73), Expect = 0.98 Identities = 35/141 (24%), Positives = 63/141 (44%), Gaps = 4/141 (2%) Frame = -3 Query: 610 LRGTIGYIAPEMIS-RSFGVISSKSDVYSFGMLLLEMAGGRRNADPNAANTSKAYYPSWV 434 L G+I ++APE+I + S +SDVY+FG++L E+ G+ N N Sbjct: 223 LSGSILWMAPEVIRMQDKNPYSFQSDVYAFGIVLYELMTGQLPYS-NINNR--------- 272 Query: 433 YDRLIQQDHVGEISTHVDVEMHELERKLCIVGLWCIQMKSNDRPTMSD---TIEMLEGSV 263 D++I G +S + + + + C++ K ++RP +IE+L S+ Sbjct: 273 -DQIIFMVGRGYLSPDLSKVRSNCPKAMKRLMAECLKKKRDERPLFPQILASIELLARSL 331 Query: 262 DALQMPSRPFFCDEGHVQTED 200 + + + QTED Sbjct: 332 PKIHRSASEPSLNRAGFQTED 352
>M3K9_HUMAN (P80192) Mitogen-activated protein kinase kinase kinase 9 (EC| 2.7.11.25) (Mixed lineage kinase 1) Length = 1104 Score = 32.3 bits (72), Expect = 1.3 Identities = 17/37 (45%), Positives = 25/37 (67%) Frame = -3 Query: 604 GTIGYIAPEMISRSFGVISSKSDVYSFGMLLLEMAGG 494 GT ++APE+I S + S SDV+S+G+LL E+ G Sbjct: 311 GTYAWMAPEVIRAS--MFSKGSDVWSYGVLLWELLTG 345
>KPC2_DROME (P13677) Protein kinase C, eye isozyme (EC 2.7.11.13) (PKC)| (dPKC53E(EY)) (Protein INAC) (Inactivation no after-potential C protein) (Photoreceptor-specific PKC) (Eye-PKC) Length = 700 Score = 32.3 bits (72), Expect = 1.3 Identities = 17/43 (39%), Positives = 26/43 (60%) Frame = -3 Query: 619 SRALRGTIGYIAPEMISRSFGVISSKSDVYSFGMLLLEMAGGR 491 +R GT Y+APE++ S+ S +D +SFG+LL E G+ Sbjct: 527 TRTFCGTPNYMAPEIV--SYDPYSIAADWWSFGVLLFEFMAGQ 567
>WNK2_HUMAN (Q9Y3S1) Serine/threonine-protein kinase WNK2 (EC 2.7.11.1)| (Protein kinase with no lysine 2) (Protein kinase, lysine-deficient 2) Length = 2297 Score = 32.3 bits (72), Expect = 1.3 Identities = 16/40 (40%), Positives = 25/40 (62%) Frame = -3 Query: 619 SRALRGTIGYIAPEMISRSFGVISSKSDVYSFGMLLLEMA 500 ++++ GT ++APEM + DVY+FGM +LEMA Sbjct: 354 AKSVIGTPEFMAPEMYEEHY---DESVDVYAFGMCMLEMA 390
>FES_FELCA (P14238) Proto-oncogene tyrosine-protein kinase FES/FPS (EC| 2.7.10.2) (C-FES) Length = 820 Score = 32.3 bits (72), Expect = 1.3 Identities = 22/59 (37%), Positives = 33/59 (55%), Gaps = 1/59 (1%) Frame = -3 Query: 637 DTSFVPSRALRGT-IGYIAPEMISRSFGVISSKSDVYSFGMLLLEMAGGRRNADPNAAN 464 D + S LR + + APE ++ +G SS+SDV+SFG+LL E + PN +N Sbjct: 708 DGIYAASGGLRQVPVKWTAPEALN--YGRYSSESDVWSFGILLWETFSLGASPYPNLSN 764
>WNK4_RAT (Q7TPK6) Serine/threonine-protein kinase WNK4 (EC 2.7.11.1)| (Protein kinase with no lysine 4) (Protein kinase, lysine-deficient 4) Length = 1222 Score = 32.3 bits (72), Expect = 1.3 Identities = 16/40 (40%), Positives = 25/40 (62%) Frame = -3 Query: 619 SRALRGTIGYIAPEMISRSFGVISSKSDVYSFGMLLLEMA 500 ++++ GT ++APEM + DVY+FGM +LEMA Sbjct: 330 AKSVIGTPEFMAPEMYEEKY---DEAVDVYAFGMCMLEMA 366
>WNK4_MOUSE (Q80UE6) Serine/threonine-protein kinase WNK4 (EC 2.7.11.1)| (Protein kinase with no lysine 4) (Protein kinase, lysine-deficient 4) Length = 1222 Score = 32.3 bits (72), Expect = 1.3 Identities = 16/40 (40%), Positives = 25/40 (62%) Frame = -3 Query: 619 SRALRGTIGYIAPEMISRSFGVISSKSDVYSFGMLLLEMA 500 ++++ GT ++APEM + DVY+FGM +LEMA Sbjct: 330 AKSVIGTPEFMAPEMYEEKY---DEAVDVYAFGMCMLEMA 366
>WNK4_HUMAN (Q96J92) Serine/threonine-protein kinase WNK4 (EC 2.7.11.1)| (Protein kinase with no lysine 4) (Protein kinase, lysine-deficient 4) Length = 1243 Score = 32.3 bits (72), Expect = 1.3 Identities = 16/40 (40%), Positives = 25/40 (62%) Frame = -3 Query: 619 SRALRGTIGYIAPEMISRSFGVISSKSDVYSFGMLLLEMA 500 ++++ GT ++APEM + DVY+FGM +LEMA Sbjct: 333 AKSVIGTPEFMAPEMYEEKY---DEAVDVYAFGMCMLEMA 369
>M3K2_ARATH (Q9FZ36) Mitogen-activated protein kinase kinase kinase 2 (EC| 2.7.11.25) (Arabidospsis NPK1-related protein kinase 2) Length = 651 Score = 32.3 bits (72), Expect = 1.3 Identities = 28/113 (24%), Positives = 54/113 (47%) Frame = -3 Query: 619 SRALRGTIGYIAPEMISRSFGVISSKSDVYSFGMLLLEMAGGRRNADPNAANTSKAYYPS 440 +++++GT ++APE+I ++ S+ D++S G ++EM T KA + S Sbjct: 230 AKSMKGTPYWMAPEVILQTGHSFSA--DIWSVGCTVIEMV------------TGKAPW-S 274 Query: 439 WVYDRLIQQDHVGEISTHVDVEMHELERKLCIVGLWCIQMKSNDRPTMSDTIE 281 Y + H+G +H + + L C+Q + N RPT S+ ++ Sbjct: 275 QQYKEIAAIFHIGTTKSHPPIP-DNISSDANDFLLKCLQQEPNLRPTASELLK 326
>FYN_HUMAN (P06241) Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2)| (p59-Fyn) (Protooncogene Syn) (SLK) Length = 536 Score = 32.3 bits (72), Expect = 1.3 Identities = 33/134 (24%), Positives = 50/134 (37%) Frame = -3 Query: 637 DTSFVPSRALRGTIGYIAPEMISRSFGVISSKSDVYSFGMLLLEMAGGRRNADPNAANTS 458 D + + + I + APE + +G + KSDV+SFG+LL E+ R P N Sbjct: 416 DNEYTARQGAKFPIKWTAPE--AALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNRE 473 Query: 457 KAYYPSWVYDRLIQQDHVGEISTHVDVEMHELERKLCIVGLWCIQMKSNDRPTMSDTIEM 278 Y QD + +HEL + C + +RPT Sbjct: 474 VLEQVERGYRMPCPQD--------CPISLHELM-------IHCWKKDPEERPTFEYLQSF 518 Query: 277 LEGSVDALQMPSRP 236 LE A + +P Sbjct: 519 LEDYFTATEPQYQP 532
>FES_FSVGA (P00542) Tyrosine-protein kinase transforming protein Fes (EC| 2.7.10.2) Length = 609 Score = 32.3 bits (72), Expect = 1.3 Identities = 22/59 (37%), Positives = 33/59 (55%), Gaps = 1/59 (1%) Frame = -3 Query: 637 DTSFVPSRALRGT-IGYIAPEMISRSFGVISSKSDVYSFGMLLLEMAGGRRNADPNAAN 464 D + S LR + + APE ++ +G SS+SDV+SFG+LL E + PN +N Sbjct: 497 DGIYAASGGLRQVPVKWTAPEALN--YGRYSSESDVWSFGILLWETFSLGASPYPNLSN 553
>TXK_MOUSE (P42682) Tyrosine-protein kinase TXK (EC 2.7.10.2) (PTK-RL-18)| (Resting lymphocyte kinase) Length = 527 Score = 32.3 bits (72), Expect = 1.3 Identities = 17/48 (35%), Positives = 27/48 (56%) Frame = -3 Query: 646 YPRDTSFVPSRALRGTIGYIAPEMISRSFGVISSKSDVYSFGMLLLEM 503 Y D ++ S + + + PE+ F SSKSDV+SFG+L+ E+ Sbjct: 414 YVLDDEYISSSGAKFPVKWCPPEVFH--FNKYSSKSDVWSFGVLMWEV 459
>INSR_AEDAE (Q93105) Insulin-like receptor precursor (EC 2.7.10.1) (MIR)| [Contains: Insulin-like receptor alpha chain; Insulin-like receptor beta chain] Length = 1390 Score = 32.3 bits (72), Expect = 1.3 Identities = 18/41 (43%), Positives = 27/41 (65%), Gaps = 5/41 (12%) Frame = -3 Query: 607 RGTIGYI-----APEMISRSFGVISSKSDVYSFGMLLLEMA 500 +GT G++ APE + G+ SS SDV+S+G++L EMA Sbjct: 1195 KGTKGFLPVRWMAPESLKD--GIFSSSSDVFSYGVVLWEMA 1233
>SSK22_YEAST (P25390) Serine/threonine-protein kinase SSK22 (EC 2.7.11.1) (MAP| kinase kinase kinase SSK22) (Suppressor of sensor kinase 22) Length = 1331 Score = 32.3 bits (72), Expect = 1.3 Identities = 20/44 (45%), Positives = 27/44 (61%), Gaps = 3/44 (6%) Frame = -3 Query: 610 LRGTIGYIAPEMISRSFGVISSK---SDVYSFGMLLLEMAGGRR 488 + GT Y+APE IS S + K DV++ G ++LEMA GRR Sbjct: 1209 MMGTPMYMAPETISGS--AVKGKLGADDVWALGCVVLEMATGRR 1250
>PGFRB_CANFA (Q6QNF3) Beta platelet-derived growth factor receptor precursor (EC| 2.7.10.1) (PDGF-R-beta) Length = 1103 Score = 32.3 bits (72), Expect = 1.3 Identities = 31/123 (25%), Positives = 55/123 (44%) Frame = -3 Query: 640 RDTSFVPSRALRGTIGYIAPEMISRSFGVISSKSDVYSFGMLLLEMAGGRRNADPNAANT 461 RD++++ + + ++APE I S + ++ SDV+SFG+LL E+ P Sbjct: 853 RDSNYISKGSTFLPLKWMAPESIFNS--LYTTLSDVWSFGILLWEIFTLGGTPYPELPMN 910 Query: 460 SKAYYPSWVYDRLIQQDHVGEISTHVDVEMHELERKLCIVGLWCIQMKSNDRPTMSDTIE 281 + Y R+ Q H + E++E+ +K C + K RP S + Sbjct: 911 EQFYNAIKRGYRMAQPAHASD-------EIYEIMQK-------CWEEKFEIRPPFSQLVL 956 Query: 280 MLE 272 +LE Sbjct: 957 LLE 959
>M3KL4_HUMAN (Q5TCX8) Mitogen-activated protein kinase kinase kinase (EC| 2.7.11.25) (Mixed lineage kinase 4) Length = 1036 Score = 32.3 bits (72), Expect = 1.3 Identities = 16/37 (43%), Positives = 25/37 (67%) Frame = -3 Query: 604 GTIGYIAPEMISRSFGVISSKSDVYSFGMLLLEMAGG 494 GT ++APE+I S + S SD++S+G+LL E+ G Sbjct: 306 GTYAWMAPEVIKSS--LFSKGSDIWSYGVLLWELLTG 340
>LIMK1_CHICK (Q8QFP8) LIM domain kinase 1 (EC 2.7.11.1) (LIMK-1) (chLIMK1)| Length = 662 Score = 32.3 bits (72), Expect = 1.3 Identities = 23/55 (41%), Positives = 35/55 (63%), Gaps = 5/55 (9%) Frame = -3 Query: 622 PSRALRGTIG----YIAPEMIS-RSFGVISSKSDVYSFGMLLLEMAGGRRNADPN 473 P R R T+ ++APEMI+ RS+ K D++SFG++L E+ GR +ADP+ Sbjct: 508 PDRKKRYTVVGNPYWMAPEMINGRSY---DEKVDIFSFGIVLCEII-GRVSADPD 558
>KIT_FELCA (Q28889) Mast/stem cell growth factor receptor precursor (EC| 2.7.10.1) (SCFR) (Proto-oncogene tyrosine-protein kinase Kit) (c-kit) Length = 978 Score = 32.3 bits (72), Expect = 1.3 Identities = 28/125 (22%), Positives = 54/125 (43%) Frame = -3 Query: 637 DTSFVPSRALRGTIGYIAPEMISRSFGVISSKSDVYSFGMLLLEMAGGRRNADPNAANTS 458 D+++V R + ++APE I V + +SDV+S+G+ L E+ + P S Sbjct: 821 DSNYVVKGNARLPVKWMAPESIFNC--VYTFESDVWSYGIFLWELFSLGSSPYPGMPVDS 878 Query: 457 KAYYPSWVYDRLIQQDHVGEISTHVDVEMHELERKLCIVGLWCIQMKSNDRPTMSDTIEM 278 K Y ++I++ H EM+++ + C RPT +++ Sbjct: 879 KFY-------KMIKEGFRMLSPEHAPAEMYDIMKT-------CWDADPLKRPTFKQIVQL 924 Query: 277 LEGSV 263 +E + Sbjct: 925 IEKQI 929
>PGFRB_HUMAN (P09619) Beta platelet-derived growth factor receptor precursor (EC| 2.7.10.1) (PDGF-R-beta) (CD140b antigen) Length = 1106 Score = 32.3 bits (72), Expect = 1.3 Identities = 31/123 (25%), Positives = 55/123 (44%) Frame = -3 Query: 640 RDTSFVPSRALRGTIGYIAPEMISRSFGVISSKSDVYSFGMLLLEMAGGRRNADPNAANT 461 RD++++ + + ++APE I S + ++ SDV+SFG+LL E+ P Sbjct: 853 RDSNYISKGSTFLPLKWMAPESIFNS--LYTTLSDVWSFGILLWEIFTLGGTPYPELPMN 910 Query: 460 SKAYYPSWVYDRLIQQDHVGEISTHVDVEMHELERKLCIVGLWCIQMKSNDRPTMSDTIE 281 + Y R+ Q H + E++E+ +K C + K RP S + Sbjct: 911 EQFYNAIKRGYRMAQPAHASD-------EIYEIMQK-------CWEEKFEIRPPFSQLVL 956 Query: 280 MLE 272 +LE Sbjct: 957 LLE 959
>YRK_CHICK (Q02977) Proto-oncogene tyrosine-protein kinase Yrk (EC 2.7.10.2)| (p60-Yrk) (Yes-related kinase) Length = 535 Score = 32.3 bits (72), Expect = 1.3 Identities = 20/58 (34%), Positives = 29/58 (50%) Frame = -3 Query: 637 DTSFVPSRALRGTIGYIAPEMISRSFGVISSKSDVYSFGMLLLEMAGGRRNADPNAAN 464 D + + + I + APE + FG + KSDV+SFG+LL E+ R P N Sbjct: 415 DNEYTARQGAKFPIKWTAPE--AALFGKFTIKSDVWSFGILLTELVTKGRVPYPGMNN 470
>TTK_MOUSE (P35761) Dual specificity protein kinase TTK (EC 2.7.12.1) (ESK)| (PYT) Length = 856 Score = 32.3 bits (72), Expect = 1.3 Identities = 20/58 (34%), Positives = 30/58 (51%), Gaps = 9/58 (15%) Frame = -3 Query: 637 DTSFVPSRALRGTIGYIAPEMI---------SRSFGVISSKSDVYSFGMLLLEMAGGR 491 DT+ + + GT+ Y+APE I S+ +S +SDV+S G +L M GR Sbjct: 673 DTTSIVKDSQVGTVNYMAPEAIRDMSSSRENSKIRTKVSPRSDVWSLGCILYYMTYGR 730
>RIPK1_MOUSE (Q60855) Receptor-interacting serine/threonine-protein kinase 1 (EC| 2.7.11.1) (Serine/threonine-protein kinase RIP) (Cell death protein RIP) (Receptor-interacting protein) Length = 656 Score = 32.3 bits (72), Expect = 1.3 Identities = 15/31 (48%), Positives = 22/31 (70%) Frame = -3 Query: 604 GTIGYIAPEMISRSFGVISSKSDVYSFGMLL 512 GT+ Y+APE ++ + KSDVYSFG++L Sbjct: 189 GTLYYMAPEHLNDINAKPTEKSDVYSFGIVL 219
>PKNA2_BIFLO (Q8G4G1) Probable serine/threonine-protein kinase pknA2 (EC| 2.7.11.1) Length = 757 Score = 32.3 bits (72), Expect = 1.3 Identities = 16/40 (40%), Positives = 25/40 (62%) Frame = -3 Query: 610 LRGTIGYIAPEMISRSFGVISSKSDVYSFGMLLLEMAGGR 491 L GT Y+APEMI + +++ D+YS G++ EM G+ Sbjct: 176 LLGTAAYLAPEMIENN--QATAQGDLYSVGIMAWEMLTGK 213
>KIT_MOUSE (P05532) Mast/stem cell growth factor receptor precursor (EC| 2.7.10.1) (SCFR) (Proto-oncogene tyrosine-protein kinase Kit) (c-kit) Length = 975 Score = 32.3 bits (72), Expect = 1.3 Identities = 28/125 (22%), Positives = 54/125 (43%) Frame = -3 Query: 637 DTSFVPSRALRGTIGYIAPEMISRSFGVISSKSDVYSFGMLLLEMAGGRRNADPNAANTS 458 D+++V R + ++APE I V + +SDV+S+G+ L E+ + P S Sbjct: 818 DSNYVVKGNARLPVKWMAPESIFSC--VYTFESDVWSYGIFLWELFSLGSSPYPGMPVDS 875 Query: 457 KAYYPSWVYDRLIQQDHVGEISTHVDVEMHELERKLCIVGLWCIQMKSNDRPTMSDTIEM 278 K Y ++I++ H EM+++ + C RPT +++ Sbjct: 876 KFY-------KMIKEGFRMVSPEHAPAEMYDVMKT-------CWDADPLKRPTFKQVVQL 921 Query: 277 LEGSV 263 +E + Sbjct: 922 IEKQI 926
>ABL2_HUMAN (P42684) Tyrosine-protein kinase ABL2 (EC 2.7.10.2) (Abelson murine| leukemia viral oncogene homolog 2) (Tyrosine kinase ARG) Length = 1182 Score = 32.3 bits (72), Expect = 1.3 Identities = 32/109 (29%), Positives = 52/109 (47%) Frame = -3 Query: 598 IGYIAPEMISRSFGVISSKSDVYSFGMLLLEMAGGRRNADPNAANTSKAYYPSWVYDRLI 419 I + APE S ++ S KSDV++FG+LL E+A + P S VYD L+ Sbjct: 449 IKWTAPE--SLAYNTFSIKSDVWAFGVLLWEIATYGMSPYPGID-------LSQVYD-LL 498 Query: 418 QQDHVGEISTHVDVEMHELERKLCIVGLWCIQMKSNDRPTMSDTIEMLE 272 ++ + E +++EL R C + DRP+ ++T + E Sbjct: 499 EKGYRMEQPEGCPPKVYELMRA-------CWKWSPADRPSFAETHQAFE 540
>IRAK3_HUMAN (Q9Y616) Interleukin-1 receptor-associated kinase 3 (EC 2.7.11.1)| (IRAK-3) (IL-1 receptor-associated kinase M) (IRAK-M) Length = 596 Score = 32.3 bits (72), Expect = 1.3 Identities = 30/126 (23%), Positives = 56/126 (44%), Gaps = 7/126 (5%) Frame = -3 Query: 592 YIAPEMISRSFGVISSKSDVYSFGMLLLEMAGGRRNA--DPNAANTSKAYYPSWVYDRLI 419 Y+ E I + G +S K+DVYSFG++++E+ G R DP + L+ Sbjct: 340 YMPEEYIRQ--GKLSIKTDVYSFGIVIMEVLTGCRVVLDDPKHIQLRD------LLRELM 391 Query: 418 QQDHVGEISTHVDVEMHELERK-----LCIVGLWCIQMKSNDRPTMSDTIEMLEGSVDAL 254 ++ + + +D ++ R C+ G C ++ RP+M + + LE + +L Sbjct: 392 EKRGLDSCLSFLDKKVPPCPRNFSAKLFCLAGR-CAATRAKLRPSMDEVLNTLESTQASL 450 Query: 253 QMPSRP 236 P Sbjct: 451 YFAEDP 456
>PKN2_CLOAB (Q97IC2) Probable serine/threonine protein kinase CAC1728 (EC| 2.7.11.1) Length = 657 Score = 32.0 bits (71), Expect = 1.7 Identities = 15/50 (30%), Positives = 31/50 (62%), Gaps = 1/50 (2%) Frame = -3 Query: 637 DTSFVPSRALRGTIGYIAPEMISRSFGV-ISSKSDVYSFGMLLLEMAGGR 491 +++ + + G+ Y++PE G+ + ++D+YSFG++L EMA G+ Sbjct: 160 ESTITTTNKVVGSAHYLSPEQAQ---GIPVDCRTDIYSFGIVLYEMATGK 206
>KIT_FSVHZ (P04048) Tyrosine-protein kinase transforming protein kit (EC| 2.7.10.1) Length = 370 Score = 32.0 bits (71), Expect = 1.7 Identities = 28/122 (22%), Positives = 53/122 (43%) Frame = -3 Query: 637 DTSFVPSRALRGTIGYIAPEMISRSFGVISSKSDVYSFGMLLLEMAGGRRNADPNAANTS 458 D+++V R + ++APE I V + +SDV+S+G+ L E+ + P S Sbjct: 258 DSNYVVKGNARLPVKWMAPESIFNC--VYTFESDVWSYGIFLWELFSLGSSPYPGMPVDS 315 Query: 457 KAYYPSWVYDRLIQQDHVGEISTHVDVEMHELERKLCIVGLWCIQMKSNDRPTMSDTIEM 278 K Y ++I++ H EM+++ + C RPT +++ Sbjct: 316 KFY-------KMIKEGFRMLSPEHAPAEMYDIMKT-------CWDADPLKRPTFKQIVQL 361 Query: 277 LE 272 +E Sbjct: 362 IE 363
>FES_FSVST (P00543) Tyrosine-protein kinase transforming protein Fes (EC| 2.7.10.2) Length = 477 Score = 32.0 bits (71), Expect = 1.7 Identities = 18/45 (40%), Positives = 28/45 (62%) Frame = -3 Query: 598 IGYIAPEMISRSFGVISSKSDVYSFGMLLLEMAGGRRNADPNAAN 464 + + APE ++ +G SS+SDV+SFG+LL E + PN +N Sbjct: 379 VKWTAPEALN--YGRYSSESDVWSFGILLWETFSLGASPYPNLSN 421
>YES_CHICK (P09324) Tyrosine-protein kinase Yes (EC 2.7.10.2) (p61-Yes)| Length = 540 Score = 32.0 bits (71), Expect = 1.7 Identities = 35/137 (25%), Positives = 55/137 (40%), Gaps = 3/137 (2%) Frame = -3 Query: 637 DTSFVPSRALRGTIGYIAPEMISRSFGVISSKSDVYSFGMLLLEMAGGRRNADPNAANTS 458 D + + + I + APE + +G + KSDV+SFG+LL E+ Sbjct: 420 DNEYTARQGAKFPIKWTAPE--AALYGRFTIKSDVWSFGILLTEL-----------VTKG 466 Query: 457 KAYYPSWVYDRLIQQDHVG---EISTHVDVEMHELERKLCIVGLWCIQMKSNDRPTMSDT 287 + YP V +++Q G +HEL KLC W + ++RPT Sbjct: 467 RVPYPGMVNREVLEQVERGYRMPCPQGCPESLHEL-MKLC----W--KKDPDERPTFEYI 519 Query: 286 IEMLEGSVDALQMPSRP 236 LE A + +P Sbjct: 520 QSFLEDYFTATEPQYQP 536
>KS6A2_MOUSE (Q9WUT3) Ribosomal protein S6 kinase alpha-2 (EC 2.7.11.1)| (S6K-alpha 2) (90 kDa ribosomal protein S6 kinase 2) (p90-RSK 2) (Ribosomal S6 kinase 3) (RSK-3) (pp90RSK3) (Protein-tyrosine kinase Mpk-9) (MAP kinase-activated protein kinase 1c) (M Length = 733 Score = 32.0 bits (71), Expect = 1.7 Identities = 16/37 (43%), Positives = 25/37 (67%) Frame = -3 Query: 604 GTIGYIAPEMISRSFGVISSKSDVYSFGMLLLEMAGG 494 GTI Y+APE+++R + +D +SFG+L+ EM G Sbjct: 221 GTIEYMAPEVVNRRGH--TQSADWWSFGVLMFEMLTG 255
>KS6A2_HUMAN (Q15349) Ribosomal protein S6 kinase alpha-2 (EC 2.7.11.1)| (S6K-alpha 2) (90 kDa ribosomal protein S6 kinase 2) (p90-RSK 2) (Ribosomal S6 kinase 3) (RSK-3) (pp90RSK3) (MAP kinase-activated protein kinase 1c) (MAPKAPK1C) Length = 733 Score = 32.0 bits (71), Expect = 1.7 Identities = 16/37 (43%), Positives = 25/37 (67%) Frame = -3 Query: 604 GTIGYIAPEMISRSFGVISSKSDVYSFGMLLLEMAGG 494 GTI Y+APE+++R + +D +SFG+L+ EM G Sbjct: 221 GTIEYMAPEVVNRRGH--TQSADWWSFGVLMFEMLTG 255
>FES_HUMAN (P07332) Proto-oncogene tyrosine-protein kinase Fes/Fps (EC| 2.7.10.2) (C-Fes) Length = 822 Score = 32.0 bits (71), Expect = 1.7 Identities = 18/45 (40%), Positives = 28/45 (62%) Frame = -3 Query: 598 IGYIAPEMISRSFGVISSKSDVYSFGMLLLEMAGGRRNADPNAAN 464 + + APE ++ +G SS+SDV+SFG+LL E + PN +N Sbjct: 724 VKWTAPEALN--YGRYSSESDVWSFGILLWETFSLGASPYPNLSN 766
>CHK1_YEAST (P38147) Serine/threonine-protein kinase CHK1 (EC 2.7.11.1)| (Checkpoint kinase 1) Length = 527 Score = 32.0 bits (71), Expect = 1.7 Identities = 15/50 (30%), Positives = 29/50 (58%) Frame = -3 Query: 640 RDTSFVPSRALRGTIGYIAPEMISRSFGVISSKSDVYSFGMLLLEMAGGR 491 +D + S RG+ Y+APE++ G + ++D++S G+LL + G+ Sbjct: 170 KDGTLRVSMDQRGSPPYMAPEVLYSEEGYYADRTDIWSIGILLFVLLTGQ 219
>KPCG_RAT (P63319) Protein kinase C gamma type (EC 2.7.11.13) (PKC-gamma)| Length = 697 Score = 32.0 bits (71), Expect = 1.7 Identities = 18/43 (41%), Positives = 25/43 (58%) Frame = -3 Query: 619 SRALRGTIGYIAPEMISRSFGVISSKSDVYSFGMLLLEMAGGR 491 +R GT YIAPE+I ++ D +SFG+LL EM G+ Sbjct: 512 TRTFCGTPDYIAPEII--AYQPYGKSVDWWSFGVLLYEMLAGQ 552
>KPCG_RABIT (P10829) Protein kinase C gamma type (EC 2.7.11.13) (PKC-gamma)| (PKC-delta) Length = 697 Score = 32.0 bits (71), Expect = 1.7 Identities = 18/43 (41%), Positives = 25/43 (58%) Frame = -3 Query: 619 SRALRGTIGYIAPEMISRSFGVISSKSDVYSFGMLLLEMAGGR 491 +R GT YIAPE+I ++ D +SFG+LL EM G+ Sbjct: 512 TRTFCGTPDYIAPEII--AYQPYGKSVDWWSFGVLLYEMLAGQ 552
>KPCG_MOUSE (P63318) Protein kinase C gamma type (EC 2.7.11.13) (PKC-gamma)| Length = 697 Score = 32.0 bits (71), Expect = 1.7 Identities = 18/43 (41%), Positives = 25/43 (58%) Frame = -3 Query: 619 SRALRGTIGYIAPEMISRSFGVISSKSDVYSFGMLLLEMAGGR 491 +R GT YIAPE+I ++ D +SFG+LL EM G+ Sbjct: 512 TRTFCGTPDYIAPEII--AYQPYGKSVDWWSFGVLLYEMLAGQ 552
>KPCG_HUMAN (P05129) Protein kinase C gamma type (EC 2.7.11.13) (PKC-gamma)| Length = 697 Score = 32.0 bits (71), Expect = 1.7 Identities = 18/43 (41%), Positives = 25/43 (58%) Frame = -3 Query: 619 SRALRGTIGYIAPEMISRSFGVISSKSDVYSFGMLLLEMAGGR 491 +R GT YIAPE+I ++ D +SFG+LL EM G+ Sbjct: 512 TRTFCGTPDYIAPEII--AYQPYGKSVDWWSFGVLLYEMLAGQ 552
>CHK1_DROME (O61661) Serine/threonine-protein kinase grp (EC 2.7.11.1) (Protein| grapes) (Chk1 homolog) Length = 512 Score = 32.0 bits (71), Expect = 1.7 Identities = 15/56 (26%), Positives = 34/56 (60%) Frame = -3 Query: 604 GTIGYIAPEMISRSFGVISSKSDVYSFGMLLLEMAGGRRNADPNAANTSKAYYPSW 437 GT+ Y+APE++ +++ + +D++S G++L+ M G D + N ++ + +W Sbjct: 182 GTLPYVAPEVLQKAYH--AQPADLWSCGVILVTMLAGELPWDQPSTNCTE--FTNW 233
>RIPK4_HUMAN (P57078) Receptor-interacting serine/threonine-protein kinase 4 (EC| 2.7.11.1) (Ankyrin repeat domain protein 3) (PKC-delta-interacting protein kinase) Length = 832 Score = 32.0 bits (71), Expect = 1.7 Identities = 14/33 (42%), Positives = 20/33 (60%) Frame = -3 Query: 610 LRGTIGYIAPEMISRSFGVISSKSDVYSFGMLL 512 L GTI Y+ PE I + +K DVYSF +++ Sbjct: 181 LFGTIAYLPPERIREKSRLFDTKHDVYSFAIVI 213
>KPCG_BOVIN (P05128) Protein kinase C gamma type (EC 2.7.11.13) (PKC-gamma)| (Fragment) Length = 682 Score = 32.0 bits (71), Expect = 1.7 Identities = 18/43 (41%), Positives = 25/43 (58%) Frame = -3 Query: 619 SRALRGTIGYIAPEMISRSFGVISSKSDVYSFGMLLLEMAGGR 491 +R GT YIAPE+I ++ D +SFG+LL EM G+ Sbjct: 497 TRTFCGTPDYIAPEII--AYQPYGKSVDWWSFGVLLYEMLAGQ 537
>HTK16_HYDAT (P53356) Tyrosine-protein kinase HTK16 (EC 2.7.10.2)| Length = 757 Score = 32.0 bits (71), Expect = 1.7 Identities = 16/35 (45%), Positives = 24/35 (68%) Frame = -3 Query: 607 RGTIGYIAPEMISRSFGVISSKSDVYSFGMLLLEM 503 R + + APE I+ +G S+KSDV+S+G+ L EM Sbjct: 647 RWPVRWYAPESIN--YGTFSTKSDVWSYGITLWEM 679
>KS6A6_HUMAN (Q9UK32) Ribosomal protein S6 kinase alpha-6 (EC 2.7.11.1)| (S6K-alpha 6) (90 kDa ribosomal protein S6 kinase 6) (p90-RSK 6) (Ribosomal S6 kinase 4) (RSK-4) (pp90RSK4) Length = 745 Score = 31.6 bits (70), Expect = 2.2 Identities = 15/37 (40%), Positives = 25/37 (67%) Frame = -3 Query: 604 GTIGYIAPEMISRSFGVISSKSDVYSFGMLLLEMAGG 494 GT+ Y+APE+++R S +D +S+G+L+ EM G Sbjct: 235 GTVEYMAPEVVNRRGH--SQSADWWSYGVLMFEMLTG 269
>FES_MOUSE (P16879) Proto-oncogene tyrosine-protein kinase Fes/Fps (EC| 2.7.10.2) (C-Fes) Length = 820 Score = 31.6 bits (70), Expect = 2.2 Identities = 18/45 (40%), Positives = 27/45 (60%) Frame = -3 Query: 598 IGYIAPEMISRSFGVISSKSDVYSFGMLLLEMAGGRRNADPNAAN 464 + + APE ++ +G SS+SDV+SFG+LL E + PN N Sbjct: 722 VKWTAPEALN--YGRYSSESDVWSFGILLWETFSLGASPYPNLTN 764
>MP2K1_CRIGR (Q63980) Dual specificity mitogen-activated protein kinase kinase 1| (EC 2.7.12.2) (MAP kinase kinase 1) (MAPKK 1) (ERK activator kinase 1) (MAPK/ERK kinase 1) (MEK1) Length = 393 Score = 31.6 bits (70), Expect = 2.2 Identities = 17/43 (39%), Positives = 26/43 (60%) Frame = -3 Query: 604 GTIGYIAPEMISRSFGVISSKSDVYSFGMLLLEMAGGRRNADP 476 GT Y++PE + + S +SD++S G+ L+EMA GR P Sbjct: 225 GTRSYMSPERLQGTH--YSVQSDIWSMGLSLVEMAVGRYPIPP 265
>SHARK_DROME (Q24145) Tyrosine-protein kinase shark (EC 2.7.10.2)| Length = 939 Score = 31.6 bits (70), Expect = 2.2 Identities = 19/49 (38%), Positives = 28/49 (57%) Frame = -3 Query: 649 LYPRDTSFVPSRALRGTIGYIAPEMISRSFGVISSKSDVYSFGMLLLEM 503 L P T + ++ R I + APE S + G+ S SDV+SFG+ + EM Sbjct: 814 LRPGSTEYQFTQGGRWPIRWYAPE--SFNLGIFSHASDVWSFGVTIWEM 860
>MPH1_SCHPO (O94235) Serine/threonine-protein kinase mph1 (EC 2.7.12.2)| Length = 678 Score = 31.6 bits (70), Expect = 2.2 Identities = 22/64 (34%), Positives = 33/64 (51%), Gaps = 9/64 (14%) Frame = -3 Query: 655 AKLYPRDTSFVPSRALRGTIGYIAPEMIS-----RSFGV----ISSKSDVYSFGMLLLEM 503 AK DT+ + + GTI Y+APE ++ + GV + SDV+S G +L +M Sbjct: 463 AKAIGNDTTNIHRDSHIGTINYMAPEALTDMNAHTNSGVKLVKLGRPSDVWSLGCILYQM 522 Query: 502 AGGR 491 GR Sbjct: 523 VYGR 526
>KS6AA_CHICK (P18652) Ribosomal protein S6 kinase 2 alpha (EC 2.7.11.1)| (Ribosomal protein S6 kinase II alpha) (S6KII-alpha) (P90-RSK) (MAP kinase-activated protein kinase 1) (MAPK-activated protein kinase 1) (MAPKAP kinase 1) (MAPKAPK-1) Length = 752 Score = 31.6 bits (70), Expect = 2.2 Identities = 15/37 (40%), Positives = 25/37 (67%) Frame = -3 Query: 604 GTIGYIAPEMISRSFGVISSKSDVYSFGMLLLEMAGG 494 GT+ Y+APE+++R S +D +S+G+L+ EM G Sbjct: 242 GTVEYMAPEVVNRQGH--SHSADWWSYGVLMFEMLTG 276
>YSK4_HUMAN (Q56UN5) SPS1/STE20-related protein kinase YSK4 (EC 2.7.11.1)| (Regulated in COPD, protein kinase) Length = 1328 Score = 31.6 bits (70), Expect = 2.2 Identities = 16/42 (38%), Positives = 27/42 (64%) Frame = -3 Query: 616 RALRGTIGYIAPEMISRSFGVISSKSDVYSFGMLLLEMAGGR 491 +++ GT ++APE+I+ S KSD++S G + EMA G+ Sbjct: 1225 KSMHGTPYWMAPEVINESG--YGRKSDIWSIGCTVFEMATGK 1264
>TXK_HUMAN (P42681) Tyrosine-protein kinase TXK (EC 2.7.10.2)| Length = 527 Score = 31.6 bits (70), Expect = 2.2 Identities = 19/48 (39%), Positives = 27/48 (56%) Frame = -3 Query: 646 YPRDTSFVPSRALRGTIGYIAPEMISRSFGVISSKSDVYSFGMLLLEM 503 Y D +V S + I + PE+ F SSKSDV+SFG+L+ E+ Sbjct: 414 YVLDDEYVSSFGAKFPIKWSPPEVFL--FNKYSSKSDVWSFGVLMWEV 459
>SRC_MOUSE (P05480) Neuronal proto-oncogene tyrosine-protein kinase Src (EC| 2.7.10.2) (p60-Src) (c-Src) (pp60c-src) Length = 540 Score = 31.6 bits (70), Expect = 2.2 Identities = 19/58 (32%), Positives = 29/58 (50%) Frame = -3 Query: 637 DTSFVPSRALRGTIGYIAPEMISRSFGVISSKSDVYSFGMLLLEMAGGRRNADPNAAN 464 D + + + I + APE + +G + KSDV+SFG+LL E+ R P N Sbjct: 420 DNEYTARQGAKFPIKWTAPE--AALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVN 475
>SRC_AVIST (P14085) Tyrosine-protein kinase transforming protein Src (EC| 2.7.10.2) (p60-Src) (v-Src) (pp60v-src) Length = 556 Score = 31.6 bits (70), Expect = 2.2 Identities = 19/58 (32%), Positives = 29/58 (50%) Frame = -3 Query: 637 DTSFVPSRALRGTIGYIAPEMISRSFGVISSKSDVYSFGMLLLEMAGGRRNADPNAAN 464 D + + + I + APE + +G + KSDV+SFG+LL E+ R P N Sbjct: 412 DNEYTARQGAKFPIKWTAPE--AALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVN 467
>SRC_AVIS2 (P15054) Tyrosine-protein kinase transforming protein Src (EC| 2.7.10.2) (p60-Src) (v-Src) (pp60v-src) Length = 586 Score = 31.6 bits (70), Expect = 2.2 Identities = 19/58 (32%), Positives = 29/58 (50%) Frame = -3 Query: 637 DTSFVPSRALRGTIGYIAPEMISRSFGVISSKSDVYSFGMLLLEMAGGRRNADPNAAN 464 D + + + I + APE + +G + KSDV+SFG+LL E+ R P N Sbjct: 412 DNEYTARQGAKFPIKWTAPE--AALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVN 467
>KS6AA_XENLA (P10665) Ribosomal protein S6 kinase 2 alpha (EC 2.7.11.1)| (Ribosomal protein S6 kinase II alpha) (S6KII-alpha) (P90-RSK) (MAP kinase-activated protein kinase 1) (MAPK-activated protein kinase 1) (MAPKAP kinase 1) (MAPKAPK-1) Length = 733 Score = 31.6 bits (70), Expect = 2.2 Identities = 15/37 (40%), Positives = 25/37 (67%) Frame = -3 Query: 604 GTIGYIAPEMISRSFGVISSKSDVYSFGMLLLEMAGG 494 GT+ Y+APE+++R S +D +S+G+L+ EM G Sbjct: 224 GTVEYMAPEVVNRQGH--SHSADWWSYGVLMFEMLTG 258
>MIPR_LYMST (Q25410) Putative molluscan insulin-related peptide(s) receptor| precursor (EC 2.7.10.1) [Contains: Putative molluscan insulin-related peptide(s) receptor alpha chain; Putative molluscan insulin-related peptide(s) receptor beta chain] Length = 1607 Score = 31.6 bits (70), Expect = 2.2 Identities = 31/109 (28%), Positives = 49/109 (44%), Gaps = 1/109 (0%) Frame = -3 Query: 598 IGYIAPEMISRSFGVISSKSDVYSFGMLLLEMAGGRRNADPNAANTSKAYYPSWVYDRLI 419 + ++APE + GV +S SDV+S+G+++ EM + A P Y L Sbjct: 1214 VRWMAPESLKD--GVFTSLSDVWSYGVVMWEM-------------VTLAAQP---YQGLS 1255 Query: 418 QQDHVGEISTHVDVEMHE-LERKLCIVGLWCIQMKSNDRPTMSDTIEML 275 ++ V IS +E+ E ++ + C K N RPT IE L Sbjct: 1256 NEEVVKFISDGYIMELPENCPNEMAYLMQHCWAKKPNQRPTFKAIIEYL 1304
>FYN_XIPHE (P27446) Proto-oncogene tyrosine-protein kinase FYN (EC 2.7.10.2)| (P59-FYN) Length = 536 Score = 31.6 bits (70), Expect = 2.2 Identities = 34/134 (25%), Positives = 49/134 (36%) Frame = -3 Query: 637 DTSFVPSRALRGTIGYIAPEMISRSFGVISSKSDVYSFGMLLLEMAGGRRNADPNAANTS 458 D + + + I + APE + +G + KSDV+SFG+LL E+ R P N Sbjct: 416 DNEYTARQGAKFPIKWTAPE--AALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNRE 473 Query: 457 KAYYPSWVYDRLIQQDHVGEISTHVDVEMHELERKLCIVGLWCIQMKSNDRPTMSDTIEM 278 Y QD +HEL L C + +RPT Sbjct: 474 VLEQVERGYRMPCPQD--------CPASLHELM-------LQCWKKDPEERPTFEYLQAF 518 Query: 277 LEGSVDALQMPSRP 236 LE A + +P Sbjct: 519 LEDYFTATEPQYQP 532
>FYN_XENLA (P13406) Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2)| (p59-Fyn) Length = 536 Score = 31.6 bits (70), Expect = 2.2 Identities = 34/134 (25%), Positives = 50/134 (37%) Frame = -3 Query: 637 DTSFVPSRALRGTIGYIAPEMISRSFGVISSKSDVYSFGMLLLEMAGGRRNADPNAANTS 458 D + + + I + APE + +G + KSDV+SFG+LL E+ R P N Sbjct: 416 DNEYTARQGAKFPIKWTAPE--AALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNRE 473 Query: 457 KAYYPSWVYDRLIQQDHVGEISTHVDVEMHELERKLCIVGLWCIQMKSNDRPTMSDTIEM 278 Y QD + +HEL L C + +RPT Sbjct: 474 VLEQVERGYRMPCPQD--------CPISLHELM-------LNCWKKDPEERPTFEYLQGF 518 Query: 277 LEGSVDALQMPSRP 236 LE A + +P Sbjct: 519 LEDYFTATEPQYQP 532
>FLT3_MOUSE (Q00342) FL cytokine receptor precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor flk-2) (Fetal liver kinase 2) (Tyrosine-protein kinase FLT3) Length = 992 Score = 31.6 bits (70), Expect = 2.2 Identities = 17/45 (37%), Positives = 29/45 (64%) Frame = -3 Query: 637 DTSFVPSRALRGTIGYIAPEMISRSFGVISSKSDVYSFGMLLLEM 503 D+S+V R + ++APE + G+ + KSDV+S+G+LL E+ Sbjct: 842 DSSYVVRGNARLPVKWMAPESLFE--GIYTIKSDVWSYGILLWEI 884
>YES_AVISY (P00527) Tyrosine-protein kinase transforming protein YES (EC| 2.7.10.2) (Fragment) Length = 528 Score = 31.6 bits (70), Expect = 2.2 Identities = 19/58 (32%), Positives = 29/58 (50%) Frame = -3 Query: 637 DTSFVPSRALRGTIGYIAPEMISRSFGVISSKSDVYSFGMLLLEMAGGRRNADPNAAN 464 D + + + I + APE + +G + KSDV+SFG+LL E+ R P N Sbjct: 413 DNEYTARQGAKFPIKWTAPE--AALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMVN 468
>SRC_RSVSE (P63185) Tyrosine-protein kinase transforming protein Src (EC| 2.7.10.2) (p60-Src) (v-Src) (pp60v-src) Length = 525 Score = 31.6 bits (70), Expect = 2.2 Identities = 19/58 (32%), Positives = 29/58 (50%) Frame = -3 Query: 637 DTSFVPSRALRGTIGYIAPEMISRSFGVISSKSDVYSFGMLLLEMAGGRRNADPNAAN 464 D + + + I + APE + +G + KSDV+SFG+LL E+ R P N Sbjct: 412 DNEYTARQGAKFPIKWTAPE--AALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMGN 467
>SRC_RSVSA (P00524) Tyrosine-protein kinase transforming protein Src (EC| 2.7.10.2) (p60-Src) (v-Src) (pp60v-src) Length = 525 Score = 31.6 bits (70), Expect = 2.2 Identities = 19/58 (32%), Positives = 29/58 (50%) Frame = -3 Query: 637 DTSFVPSRALRGTIGYIAPEMISRSFGVISSKSDVYSFGMLLLEMAGGRRNADPNAAN 464 D + + + I + APE + +G + KSDV+SFG+LL E+ R P N Sbjct: 412 DNEYTARQGAKFPIKWTAPE--AALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMGN 467
>SRC_RSVP (P00526) Tyrosine-protein kinase transforming protein Src (EC| 2.7.10.2) (p60-Src) (v-Src) (pp60v-src) Length = 525 Score = 31.6 bits (70), Expect = 2.2 Identities = 19/58 (32%), Positives = 29/58 (50%) Frame = -3 Query: 637 DTSFVPSRALRGTIGYIAPEMISRSFGVISSKSDVYSFGMLLLEMAGGRRNADPNAAN 464 D + + + I + APE + +G + KSDV+SFG+LL E+ R P N Sbjct: 412 DNEYTARQGAKFPIKWTAPE--AALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVN 467
>SRC_RSVH1 (P25020) Tyrosine-protein kinase transforming protein Src (EC| 2.7.10.2) (p60-Src) (v-Src) (pp60v-src) Length = 525 Score = 31.6 bits (70), Expect = 2.2 Identities = 19/58 (32%), Positives = 29/58 (50%) Frame = -3 Query: 637 DTSFVPSRALRGTIGYIAPEMISRSFGVISSKSDVYSFGMLLLEMAGGRRNADPNAAN 464 D + + + I + APE + +G + KSDV+SFG+LL E+ R P N Sbjct: 412 DNEYTARQGAKFPIKWTAPE--AALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVN 467
>SRC_CHICK (P00523) Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2)| (p60-Src) (c-Src) (pp60c-src) Length = 532 Score = 31.6 bits (70), Expect = 2.2 Identities = 19/58 (32%), Positives = 29/58 (50%) Frame = -3 Query: 637 DTSFVPSRALRGTIGYIAPEMISRSFGVISSKSDVYSFGMLLLEMAGGRRNADPNAAN 464 D + + + I + APE + +G + KSDV+SFG+LL E+ R P N Sbjct: 412 DNEYTARQGAKFPIKWTAPE--AALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVN 467
>SRC_AVISR (P00525) Tyrosine-protein kinase transforming protein Src (EC| 2.7.10.2) (p60-Src) (v-Src) (pp60v-src) Length = 525 Score = 31.6 bits (70), Expect = 2.2 Identities = 19/58 (32%), Positives = 29/58 (50%) Frame = -3 Query: 637 DTSFVPSRALRGTIGYIAPEMISRSFGVISSKSDVYSFGMLLLEMAGGRRNADPNAAN 464 D + + + I + APE + +G + KSDV+SFG+LL E+ R P N Sbjct: 412 DNEYTARQGAKFPIKWTAPE--AALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMGN 467
>MP2K1_RAT (Q01986) Dual specificity mitogen-activated protein kinase kinase 1| (EC 2.7.12.2) (MAP kinase kinase 1) (MAPKK 1) (ERK activator kinase 1) (MAPK/ERK kinase 1) (MEK1) Length = 392 Score = 31.6 bits (70), Expect = 2.2 Identities = 17/43 (39%), Positives = 26/43 (60%) Frame = -3 Query: 604 GTIGYIAPEMISRSFGVISSKSDVYSFGMLLLEMAGGRRNADP 476 GT Y++PE + + S +SD++S G+ L+EMA GR P Sbjct: 224 GTRSYMSPERLQGTH--YSVQSDIWSMGLSLVEMAVGRYPIPP 264
>MP2K1_RABIT (P29678) Dual specificity mitogen-activated protein kinase kinase 1| (EC 2.7.12.2) (MAP kinase kinase 1) (MAPKK 1) (ERK activator kinase 1) (MAPK/ERK kinase 1) (MEK1) Length = 392 Score = 31.6 bits (70), Expect = 2.2 Identities = 17/43 (39%), Positives = 26/43 (60%) Frame = -3 Query: 604 GTIGYIAPEMISRSFGVISSKSDVYSFGMLLLEMAGGRRNADP 476 GT Y++PE + + S +SD++S G+ L+EMA GR P Sbjct: 224 GTRSYMSPERLQGTH--YSVQSDIWSMGLSLVEMAVGRYPIPP 264
>MP2K1_MOUSE (P31938) Dual specificity mitogen-activated protein kinase kinase 1| (EC 2.7.12.2) (MAP kinase kinase 1) (MAPKK 1) (ERK activator kinase 1) (MAPK/ERK kinase 1) (MEK1) Length = 392 Score = 31.6 bits (70), Expect = 2.2 Identities = 17/43 (39%), Positives = 26/43 (60%) Frame = -3 Query: 604 GTIGYIAPEMISRSFGVISSKSDVYSFGMLLLEMAGGRRNADP 476 GT Y++PE + + S +SD++S G+ L+EMA GR P Sbjct: 224 GTRSYMSPERLQGTH--YSVQSDIWSMGLSLVEMAVGRYPIPP 264
>MP2K1_HUMAN (Q02750) Dual specificity mitogen-activated protein kinase kinase 1| (EC 2.7.12.2) (MAP kinase kinase 1) (MAPKK 1) (ERK activator kinase 1) (MAPK/ERK kinase 1) (MEK1) Length = 392 Score = 31.6 bits (70), Expect = 2.2 Identities = 17/43 (39%), Positives = 26/43 (60%) Frame = -3 Query: 604 GTIGYIAPEMISRSFGVISSKSDVYSFGMLLLEMAGGRRNADP 476 GT Y++PE + + S +SD++S G+ L+EMA GR P Sbjct: 224 GTRSYMSPERLQGTH--YSVQSDIWSMGLSLVEMAVGRYPIPP 264
>BMR1A_HUMAN (P36894) Bone morphogenetic protein receptor type IA precursor (EC| 2.7.11.30) (Serine/threonine-protein kinase receptor R5) (SKR5) (Activin receptor-like kinase 3) (ALK-3) (CD292 antigen) Length = 532 Score = 31.6 bits (70), Expect = 2.2 Identities = 17/46 (36%), Positives = 26/46 (56%), Gaps = 4/46 (8%) Frame = -3 Query: 625 VPSRALRGTIGYIAPEMISRSFGVISSK----SDVYSFGMLLLEMA 500 VP GT Y+APE++ S + +D+YSFG+++ EMA Sbjct: 396 VPLNTRVGTKRYMAPEVLDESLNKNHFQPYIMADIYSFGLIIWEMA 441
>KS6A1_HUMAN (Q15418) Ribosomal protein S6 kinase alpha-1 (EC 2.7.11.1)| (S6K-alpha 1) (90 kDa ribosomal protein S6 kinase 1) (p90-RSK 1) (Ribosomal S6 kinase 1) (RSK-1) (pp90RSK1) (MAP kinase-activated protein kinase 1a) (MAPKAPK1A) Length = 735 Score = 31.6 bits (70), Expect = 2.2 Identities = 15/37 (40%), Positives = 25/37 (67%) Frame = -3 Query: 604 GTIGYIAPEMISRSFGVISSKSDVYSFGMLLLEMAGG 494 GT+ Y+APE+++R S +D +S+G+L+ EM G Sbjct: 224 GTVEYMAPEVVNRQGH--SHSADWWSYGVLMFEMLTG 258
>SRC_RAT (Q9WUD9) Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2)| (p60-Src) (c-Src) (pp60c-src) Length = 535 Score = 31.6 bits (70), Expect = 2.2 Identities = 19/58 (32%), Positives = 29/58 (50%) Frame = -3 Query: 637 DTSFVPSRALRGTIGYIAPEMISRSFGVISSKSDVYSFGMLLLEMAGGRRNADPNAAN 464 D + + + I + APE + +G + KSDV+SFG+LL E+ R P N Sbjct: 415 DNEYTARQGAKFPIKWTAPE--AALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVN 470
>SRC_HUMAN (P12931) Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2)| (p60-Src) (c-Src) (pp60c-src) Length = 535 Score = 31.6 bits (70), Expect = 2.2 Identities = 19/58 (32%), Positives = 29/58 (50%) Frame = -3 Query: 637 DTSFVPSRALRGTIGYIAPEMISRSFGVISSKSDVYSFGMLLLEMAGGRRNADPNAAN 464 D + + + I + APE + +G + KSDV+SFG+LL E+ R P N Sbjct: 415 DNEYTARQGAKFPIKWTAPE--AALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVN 470
>SRC_AVISS (P14084) Tyrosine-protein kinase transforming protein Src (EC| 2.7.10.2) (p60-Src) (v-Src) (pp60v-src) Length = 567 Score = 31.6 bits (70), Expect = 2.2 Identities = 19/58 (32%), Positives = 29/58 (50%) Frame = -3 Query: 637 DTSFVPSRALRGTIGYIAPEMISRSFGVISSKSDVYSFGMLLLEMAGGRRNADPNAAN 464 D + + + I + APE + +G + KSDV+SFG+LL E+ R P N Sbjct: 412 DNEYTARQGAKFPIKWTAPE--AALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVN 467
>SRC2_XENLA (P13116) Tyrosine-protein kinase Src-2 (EC 2.7.10.2) (p60-Src-2)| Length = 531 Score = 31.6 bits (70), Expect = 2.2 Identities = 19/58 (32%), Positives = 29/58 (50%) Frame = -3 Query: 637 DTSFVPSRALRGTIGYIAPEMISRSFGVISSKSDVYSFGMLLLEMAGGRRNADPNAAN 464 D + + + I + APE + +G + KSDV+SFG+LL E+ R P N Sbjct: 411 DNEYTARQGAKFPIKWTAPE--AALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVN 466
>SRC1_XENLA (P13115) Tyrosine-protein kinase Src-1 (EC 2.7.10.2) (p60-Src-1)| Length = 531 Score = 31.6 bits (70), Expect = 2.2 Identities = 19/58 (32%), Positives = 29/58 (50%) Frame = -3 Query: 637 DTSFVPSRALRGTIGYIAPEMISRSFGVISSKSDVYSFGMLLLEMAGGRRNADPNAAN 464 D + + + I + APE + +G + KSDV+SFG+LL E+ R P N Sbjct: 411 DNEYTARQGAKFPIKWTAPE--AALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVN 466
>KS6A3_MOUSE (P18654) Ribosomal protein S6 kinase alpha-3 (EC 2.7.11.1)| (S6K-alpha 3) (90 kDa ribosomal protein S6 kinase 3) (p90-RSK 3) (Ribosomal S6 kinase 2) (RSK-2) (pp90RSK2) (MAP kinase-activated protein kinase 1b) (MAPKAPK1B) Length = 740 Score = 31.6 bits (70), Expect = 2.2 Identities = 15/37 (40%), Positives = 25/37 (67%) Frame = -3 Query: 604 GTIGYIAPEMISRSFGVISSKSDVYSFGMLLLEMAGG 494 GT+ Y+APE+++R + +D +SFG+L+ EM G Sbjct: 230 GTVEYMAPEVVNRRGH--TQSADWWSFGVLMFEMLTG 264
>KS6A3_HUMAN (P51812) Ribosomal protein S6 kinase alpha-3 (EC 2.7.11.1)| (S6K-alpha 3) (90 kDa ribosomal protein S6 kinase 3) (p90-RSK 3) (Ribosomal S6 kinase 2) (RSK-2) (pp90RSK2) (Insulin-stimulated protein kinase 1) (ISPK-1) (MAP kinase-activated protei Length = 740 Score = 31.6 bits (70), Expect = 2.2 Identities = 15/37 (40%), Positives = 25/37 (67%) Frame = -3 Query: 604 GTIGYIAPEMISRSFGVISSKSDVYSFGMLLLEMAGG 494 GT+ Y+APE+++R + +D +SFG+L+ EM G Sbjct: 230 GTVEYMAPEVVNRRGH--TQSADWWSFGVLMFEMLTG 264
>FYN_MOUSE (P39688) Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2)| (p59-Fyn) Length = 533 Score = 31.6 bits (70), Expect = 2.2 Identities = 33/134 (24%), Positives = 50/134 (37%) Frame = -3 Query: 637 DTSFVPSRALRGTIGYIAPEMISRSFGVISSKSDVYSFGMLLLEMAGGRRNADPNAANTS 458 D + + + I + APE + +G + KSDV+SFG+LL E+ R P N Sbjct: 413 DNEYTARQGAKFPIKWTAPE--AALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNRE 470 Query: 457 KAYYPSWVYDRLIQQDHVGEISTHVDVEMHELERKLCIVGLWCIQMKSNDRPTMSDTIEM 278 Y QD + +HEL + C + +RPT Sbjct: 471 VLEQVERGYRMPCPQD--------CPISLHELM-------IHCWKKDPEERPTFEYLQGF 515 Query: 277 LEGSVDALQMPSRP 236 LE A + +P Sbjct: 516 LEDYFTATEPQYQP 529
>FYN_CHICK (Q05876) Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2)| (p59-Fyn) Length = 533 Score = 31.6 bits (70), Expect = 2.2 Identities = 33/134 (24%), Positives = 50/134 (37%) Frame = -3 Query: 637 DTSFVPSRALRGTIGYIAPEMISRSFGVISSKSDVYSFGMLLLEMAGGRRNADPNAANTS 458 D + + + I + APE + +G + KSDV+SFG+LL E+ R P N Sbjct: 413 DNEYTARQGAKFPIKWTAPE--AALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNRE 470 Query: 457 KAYYPSWVYDRLIQQDHVGEISTHVDVEMHELERKLCIVGLWCIQMKSNDRPTMSDTIEM 278 Y QD + +HEL + C + +RPT Sbjct: 471 VLEQVERGYRMPCPQD--------CPISLHELM-------IHCWKKDPEERPTFEYLQGF 515 Query: 277 LEGSVDALQMPSRP 236 LE A + +P Sbjct: 516 LEDYFTATEPQYQP 529
>PKNB_MYCLE (P54744) Probable serine/threonine-protein kinase pknB (EC| 2.7.11.1) Length = 622 Score = 31.6 bits (70), Expect = 2.2 Identities = 18/54 (33%), Positives = 28/54 (51%) Frame = -3 Query: 655 AKLYPRDTSFVPSRALRGTIGYIAPEMISRSFGVISSKSDVYSFGMLLLEMAGG 494 A+ TS + A+ GT Y++PE + ++SDVYS G +L E+ G Sbjct: 160 ARAIADSTSVTQTAAVIGTAQYLSPEQARGDS--VDARSDVYSLGCVLYEILTG 211
>RAF1_XENLA (P09560) RAF proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (C-RAF) Length = 638 Score = 31.2 bits (69), Expect = 2.8 Identities = 17/40 (42%), Positives = 27/40 (67%), Gaps = 1/40 (2%) Frame = -3 Query: 610 LRGTIGYIAPEMIS-RSFGVISSKSDVYSFGMLLLEMAGG 494 L G+I ++APE+I + S +SDVYS+G++L E+ G Sbjct: 496 LTGSILWMAPEVIRMQDNNPFSFQSDVYSYGIVLYELMTG 535
>MP2K1_XENLA (Q05116) Dual specificity mitogen-activated protein kinase kinase 1| (EC 2.7.12.2) (MAP kinase kinase 1) (MAPKK 1) (ERK activator kinase 1) (MAPK/ERK kinase 1) (MEK1) Length = 394 Score = 31.2 bits (69), Expect = 2.8 Identities = 17/43 (39%), Positives = 26/43 (60%) Frame = -3 Query: 604 GTIGYIAPEMISRSFGVISSKSDVYSFGMLLLEMAGGRRNADP 476 GT Y++PE + + S +SD++S G+ L+EMA GR P Sbjct: 224 GTRSYMSPERLQGTH--YSVQSDIWSMGLSLVEMAIGRYPIPP 264
>JAK3_HUMAN (P52333) Tyrosine-protein kinase JAK3 (EC 2.7.10.2) (Janus kinase 3)| (JAK-3) (Leukocyte janus kinase) (L-JAK) Length = 1124 Score = 31.2 bits (69), Expect = 2.8 Identities = 20/52 (38%), Positives = 31/52 (59%), Gaps = 1/52 (1%) Frame = -3 Query: 655 AKLYPRDTSFVPSRAL-RGTIGYIAPEMISRSFGVISSKSDVYSFGMLLLEM 503 AKL P D + R + I + APE +S + + S +SDV+SFG++L E+ Sbjct: 971 AKLLPLDKDYYVVREPGQSPIFWYAPESLSDN--IFSRQSDVWSFGVVLYEL 1020
>LRRK2_MOUSE (Q5S006) Leucine-rich repeat serine/threonine-protein kinase 2 (EC| 2.7.11.1) Length = 2527 Score = 31.2 bits (69), Expect = 2.8 Identities = 15/31 (48%), Positives = 23/31 (74%) Frame = -3 Query: 604 GTIGYIAPEMISRSFGVISSKSDVYSFGMLL 512 GT G+ APE ++R + + ++DVYSFG+LL Sbjct: 2034 GTPGFRAPE-VARGNVIYNQQADVYSFGLLL 2063
>VAB1_CAEEL (O61460) Ephrin receptor 1 precursor (EC 2.7.10.1) (Tyrosine-protein| kinase Eph receptor) (Variable abnormal protein 1) Length = 1122 Score = 31.2 bits (69), Expect = 2.8 Identities = 28/108 (25%), Positives = 50/108 (46%), Gaps = 3/108 (2%) Frame = -3 Query: 598 IGYIAPEMIS-RSFGVISSKSDVYSFGMLLLEMAG-GRRNADPNAANTSKAYYPSWVYDR 425 + + APE I+ R F + SDV+SFG+++ E+ G R Y W + Sbjct: 894 VRWTAPEAITHRKF---TPSSDVWSFGVVIWEVCSFGERP------------YWDWTNQK 938 Query: 424 LIQQDHVG-EISTHVDVEMHELERKLCIVGLWCIQMKSNDRPTMSDTI 284 +I + +G + +D M L + WC +M+ ++RPT + + Sbjct: 939 VISEVMIGYRLPPPMDCPMG-----LYRIAQWCWKMERHERPTFTQLL 981
>PTK6_MOUSE (Q64434) Tyrosine-protein kinase 6 (EC 2.7.10.2) (SRC-related| intestinal kinase) Length = 451 Score = 31.2 bits (69), Expect = 2.8 Identities = 19/43 (44%), Positives = 26/43 (60%) Frame = -3 Query: 592 YIAPEMISRSFGVISSKSDVYSFGMLLLEMAGGRRNADPNAAN 464 + APE +SR G S KSDV+SFG+LL E+ + P +N Sbjct: 353 WTAPEALSR--GHYSIKSDVWSFGVLLHEIFSRGQMPYPGMSN 393
>SRC_RSVPA (P31693) Tyrosine-protein kinase transforming protein Src (EC| 2.7.10.2) (p60-Src) (v-Src) (pp60v-src) Length = 522 Score = 31.2 bits (69), Expect = 2.8 Identities = 19/58 (32%), Positives = 28/58 (48%) Frame = -3 Query: 637 DTSFVPSRALRGTIGYIAPEMISRSFGVISSKSDVYSFGMLLLEMAGGRRNADPNAAN 464 D + R + + APE + +G + KSDV+SFG+LL E+ R P N Sbjct: 409 DNEYTARPGARFPVKWTAPE--AALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVN 464
>BMR1A_MOUSE (P36895) Bone morphogenetic protein receptor type IA precursor (EC| 2.7.11.30) (Serine/threonine-protein kinase receptor R5) (SKR5) (Activin receptor-like kinase 3) (ALK-3) (BMP-2/BMP-4 receptor) Length = 532 Score = 31.2 bits (69), Expect = 2.8 Identities = 16/46 (34%), Positives = 26/46 (56%), Gaps = 4/46 (8%) Frame = -3 Query: 625 VPSRALRGTIGYIAPEMISRSFGVISSK----SDVYSFGMLLLEMA 500 +P GT Y+APE++ S + +D+YSFG+++ EMA Sbjct: 396 IPLNTRVGTKRYMAPEVLDESLNKNHFQPYIMADIYSFGLIIWEMA 441
>PKNL_MYCTU (O53510) Probable serine/threonine-protein kinase pknL (EC| 2.7.11.1) Length = 399 Score = 31.2 bits (69), Expect = 2.8 Identities = 16/46 (34%), Positives = 25/46 (54%) Frame = -3 Query: 631 SFVPSRALRGTIGYIAPEMISRSFGVISSKSDVYSFGMLLLEMAGG 494 S + + GT Y++PE + G +SDVYS G+L+ E+ G Sbjct: 171 SITSTGVILGTAAYLSPEQVRD--GNADPRSDVYSVGVLVYELLTG 214
>PKNL_MYCBO (Q7TYY6) Probable serine/threonine-protein kinase pknL (EC| 2.7.11.1) Length = 399 Score = 31.2 bits (69), Expect = 2.8 Identities = 16/46 (34%), Positives = 25/46 (54%) Frame = -3 Query: 631 SFVPSRALRGTIGYIAPEMISRSFGVISSKSDVYSFGMLLLEMAGG 494 S + + GT Y++PE + G +SDVYS G+L+ E+ G Sbjct: 171 SITSTGVILGTAAYLSPEQVRD--GNADPRSDVYSVGVLVYELLTG 214
>PKN2_CORGL (Q8NU97) Serine/threonine protein kinases pknA (EC 2.7.11.1)| Length = 469 Score = 31.2 bits (69), Expect = 2.8 Identities = 15/39 (38%), Positives = 23/39 (58%) Frame = -3 Query: 604 GTIGYIAPEMISRSFGVISSKSDVYSFGMLLLEMAGGRR 488 GT Y++PE +++ SD+YS G++ EM GRR Sbjct: 186 GTAQYVSPEQAQGK--EVTAASDIYSLGVVGYEMMAGRR 222
>MP2K1_SERCA (Q91447) Dual specificity mitogen-activated protein kinase kinase 1| (EC 2.7.12.2) (MAP kinase kinase 1) (MAPKK 1) (ERK activator kinase 1) (MAPK/ERK kinase 1) (MEK1) (Fragment) Length = 388 Score = 31.2 bits (69), Expect = 2.8 Identities = 17/43 (39%), Positives = 26/43 (60%) Frame = -3 Query: 604 GTIGYIAPEMISRSFGVISSKSDVYSFGMLLLEMAGGRRNADP 476 GT Y++PE + + S +SD++S G+ L+EMA GR P Sbjct: 218 GTRSYMSPERLQGTH--YSVQSDIWSMGLSLVEMAIGRYPIPP 258
>KPCB_RAT (P68403) Protein kinase C beta type (EC 2.7.11.13) (PKC-beta)| (PKC-B) Length = 670 Score = 30.8 bits (68), Expect = 3.7 Identities = 17/45 (37%), Positives = 26/45 (57%) Frame = -3 Query: 625 VPSRALRGTIGYIAPEMISRSFGVISSKSDVYSFGMLLLEMAGGR 491 V ++ GT YIAPE+I ++ D ++FG+LL EM G+ Sbjct: 495 VTTKTFCGTPDYIAPEII--AYQPYGKSVDWWAFGVLLYEMLAGQ 537
>KPCB_RABIT (P05772) Protein kinase C beta type (EC 2.7.11.13) (PKC-beta)| (PKC-B) Length = 670 Score = 30.8 bits (68), Expect = 3.7 Identities = 17/45 (37%), Positives = 26/45 (57%) Frame = -3 Query: 625 VPSRALRGTIGYIAPEMISRSFGVISSKSDVYSFGMLLLEMAGGR 491 V ++ GT YIAPE+I ++ D ++FG+LL EM G+ Sbjct: 495 VTTKTFCGTPDYIAPEII--AYQPYGKSVDWWAFGVLLYEMLAGQ 537
>KPCB_HUMAN (P05771) Protein kinase C beta type (EC 2.7.11.13) (PKC-beta)| (PKC-B) Length = 670 Score = 30.8 bits (68), Expect = 3.7 Identities = 17/45 (37%), Positives = 26/45 (57%) Frame = -3 Query: 625 VPSRALRGTIGYIAPEMISRSFGVISSKSDVYSFGMLLLEMAGGR 491 V ++ GT YIAPE+I ++ D ++FG+LL EM G+ Sbjct: 495 VTTKTFCGTPDYIAPEII--AYQPYGKSVDWWAFGVLLYEMLAGQ 537
>STE11_YEAST (P23561) Serine/threonine-protein kinase STE11 (EC 2.7.11.1)| Length = 738 Score = 30.8 bits (68), Expect = 3.7 Identities = 14/54 (25%), Positives = 35/54 (64%) Frame = -3 Query: 652 KLYPRDTSFVPSRALRGTIGYIAPEMISRSFGVISSKSDVYSFGMLLLEMAGGR 491 KL P + +L+G++ +++PE++ ++ ++K+D++S G +++EM G+ Sbjct: 624 KLSPLNKKQNKRASLQGSVFWMSPEVVKQT--ATTAKADIWSTGCVVIEMFTGK 675
>PMYT1_MOUSE (Q9ESG9) Membrane-associated tyrosine- and threonine-specific| cdc2-inhibitory kinase (EC 2.7.11.1) (Myt1 kinase) Length = 490 Score = 30.8 bits (68), Expect = 3.7 Identities = 15/38 (39%), Positives = 25/38 (65%) Frame = -3 Query: 613 ALRGTIGYIAPEMISRSFGVISSKSDVYSFGMLLLEMA 500 A G Y+APE++ S+G + +DV+S G+ +LE+A Sbjct: 257 AQEGDPRYMAPELLQGSYG---TAADVFSLGLTILEVA 291
>KPCA_RAT (P05696) Protein kinase C alpha type (EC 2.7.11.13) (PKC-alpha)| (PKC-A) Length = 671 Score = 30.8 bits (68), Expect = 3.7 Identities = 17/45 (37%), Positives = 26/45 (57%) Frame = -3 Query: 625 VPSRALRGTIGYIAPEMISRSFGVISSKSDVYSFGMLLLEMAGGR 491 V +R GT YIAPE+I ++ D +++G+LL EM G+ Sbjct: 492 VTTRTFCGTPDYIAPEII--AYQPYGKSVDWWAYGVLLYEMLAGQ 534
>KPCA_RABIT (P10102) Protein kinase C alpha type (EC 2.7.11.13) (PKC-alpha)| (PKC-A) Length = 671 Score = 30.8 bits (68), Expect = 3.7 Identities = 17/45 (37%), Positives = 26/45 (57%) Frame = -3 Query: 625 VPSRALRGTIGYIAPEMISRSFGVISSKSDVYSFGMLLLEMAGGR 491 V +R GT YIAPE+I ++ D +++G+LL EM G+ Sbjct: 492 VTTRTFCGTPDYIAPEII--AYQPYGKSVDWWAYGVLLYEMLAGQ 534
>KPCA_MOUSE (P20444) Protein kinase C alpha type (EC 2.7.11.13) (PKC-alpha)| (PKC-A) Length = 671 Score = 30.8 bits (68), Expect = 3.7 Identities = 17/45 (37%), Positives = 26/45 (57%) Frame = -3 Query: 625 VPSRALRGTIGYIAPEMISRSFGVISSKSDVYSFGMLLLEMAGGR 491 V +R GT YIAPE+I ++ D +++G+LL EM G+ Sbjct: 492 VTTRTFCGTPDYIAPEII--AYQPYGKSVDWWAYGVLLYEMLAGQ 534
>KPCA_HUMAN (P17252) Protein kinase C alpha type (EC 2.7.11.13) (PKC-alpha)| (PKC-A) Length = 671 Score = 30.8 bits (68), Expect = 3.7 Identities = 17/45 (37%), Positives = 26/45 (57%) Frame = -3 Query: 625 VPSRALRGTIGYIAPEMISRSFGVISSKSDVYSFGMLLLEMAGGR 491 V +R GT YIAPE+I ++ D +++G+LL EM G+ Sbjct: 492 VTTRTFCGTPDYIAPEII--AYQPYGKSVDWWAYGVLLYEMLAGQ 534
>KPCA_BOVIN (P04409) Protein kinase C alpha type (EC 2.7.11.13) (PKC-alpha)| (PKC-A) Length = 671 Score = 30.8 bits (68), Expect = 3.7 Identities = 17/45 (37%), Positives = 26/45 (57%) Frame = -3 Query: 625 VPSRALRGTIGYIAPEMISRSFGVISSKSDVYSFGMLLLEMAGGR 491 V +R GT YIAPE+I ++ D +++G+LL EM G+ Sbjct: 492 VTTRTFCGTPDYIAPEII--AYQPYGKSVDWWAYGVLLYEMLAGQ 534
>KPCB_MOUSE (P68404) Protein kinase C beta type (EC 2.7.11.13) (PKC-beta)| (PKC-B) Length = 672 Score = 30.8 bits (68), Expect = 3.7 Identities = 17/45 (37%), Positives = 26/45 (57%) Frame = -3 Query: 625 VPSRALRGTIGYIAPEMISRSFGVISSKSDVYSFGMLLLEMAGGR 491 V ++ GT YIAPE+I ++ D ++FG+LL EM G+ Sbjct: 495 VTTKTFCGTPDYIAPEII--AYQPYGKSVDWWAFGVLLYEMLAGQ 537
>KPCB_BOVIN (P05126) Protein kinase C beta type (EC 2.7.11.13) (PKC-beta)| (PKC-B) Length = 672 Score = 30.8 bits (68), Expect = 3.7 Identities = 17/45 (37%), Positives = 26/45 (57%) Frame = -3 Query: 625 VPSRALRGTIGYIAPEMISRSFGVISSKSDVYSFGMLLLEMAGGR 491 V ++ GT YIAPE+I ++ D ++FG+LL EM G+ Sbjct: 495 VTTKTFCGTPDYIAPEII--AYQPYGKSVDWWAFGVLLYEMLAGQ 537
>ILPR_BRALA (O02466) Insulin-like peptide receptor precursor (EC 2.7.10.1) (ILP| receptor) [Contains: Insulin-like peptide receptor alpha chain; Insulin-like peptide receptor beta chain] Length = 1363 Score = 30.8 bits (68), Expect = 3.7 Identities = 15/33 (45%), Positives = 25/33 (75%) Frame = -3 Query: 598 IGYIAPEMISRSFGVISSKSDVYSFGMLLLEMA 500 + +++PE S GV +S+SDV+S+G++L EMA Sbjct: 1189 VRWMSPE--SLKVGVFTSQSDVWSYGVVLWEMA 1219
>KS6AB_XENLA (P10666) Ribosomal protein S6 kinase 2 beta (EC 2.7.11.1)| (Ribosomal protein S6 kinase II beta) (S6KII-beta) (P90-RSK) Length = 629 Score = 30.8 bits (68), Expect = 3.7 Identities = 15/37 (40%), Positives = 25/37 (67%) Frame = -3 Query: 604 GTIGYIAPEMISRSFGVISSKSDVYSFGMLLLEMAGG 494 GT+ Y+APE+++R S +D +S+G+L+ EM G Sbjct: 224 GTVEYMAPEVVNRQGH--SHGADWWSYGVLMFEMLTG 258
>TEC_MOUSE (P24604) Tyrosine-protein kinase Tec (EC 2.7.10.2)| Length = 630 Score = 30.8 bits (68), Expect = 3.7 Identities = 16/48 (33%), Positives = 27/48 (56%) Frame = -3 Query: 646 YPRDTSFVPSRALRGTIGYIAPEMISRSFGVISSKSDVYSFGMLLLEM 503 Y D + S + + + PE+ + + SSKSDV+SFG+L+ E+ Sbjct: 512 YVLDDQYTSSSGAKFPVKWCPPEVFN--YSRFSSKSDVWSFGVLMWEI 557
>KS6A_CAEEL (Q21734) Putative ribosomal protein S6 kinase alpha (EC 2.7.11.1)| Length = 784 Score = 30.8 bits (68), Expect = 3.7 Identities = 16/37 (43%), Positives = 24/37 (64%) Frame = -3 Query: 604 GTIGYIAPEMISRSFGVISSKSDVYSFGMLLLEMAGG 494 GT+ Y+APE+I+R S +D +S G+L+ EM G Sbjct: 266 GTVEYMAPEVINRRGH--SMAADFWSLGVLMFEMLTG 300
>KS6A1_RAT (Q63531) Ribosomal protein S6 kinase alpha-1 (EC 2.7.11.1)| (S6K-alpha 1) (90 kDa ribosomal protein S6 kinase 1) (p90-RSK 1) (Ribosomal S6 kinase 1) (RSK-1) (pp90RSK1) (MAP kinase-activated protein kinase 1a) (MAPKAPK1A) Length = 735 Score = 30.8 bits (68), Expect = 3.7 Identities = 15/37 (40%), Positives = 25/37 (67%) Frame = -3 Query: 604 GTIGYIAPEMISRSFGVISSKSDVYSFGMLLLEMAGG 494 GT+ Y+APE+++R S +D +S+G+L+ EM G Sbjct: 224 GTVEYMAPEVVNRQGHTHS--ADWWSYGVLMFEMLTG 258
>EPHAA_HUMAN (Q5JZY3) Ephrin type-A receptor 10 precursor (EC 2.7.10.1)| Length = 1008 Score = 30.8 bits (68), Expect = 3.7 Identities = 23/55 (41%), Positives = 30/55 (54%), Gaps = 3/55 (5%) Frame = -3 Query: 643 PRDTSFVPSRALRGTIG--YIAPEMISRSFGVISSKSDVYSFGMLLLE-MAGGRR 488 PRD S + G + APE + FG SS SDV+SFG+++ E MA G R Sbjct: 793 PRDRSEAVYTTMSGRSPALWAAPETLQ--FGHFSSASDVWSFGIIMWEVMAFGER 845
>PKNB_BIFLO (Q8G6P9) Probable serine/threonine-protein kinase pknB (EC| 2.7.11.1) Length = 690 Score = 30.8 bits (68), Expect = 3.7 Identities = 23/77 (29%), Positives = 36/77 (46%) Frame = -3 Query: 619 SRALRGTIGYIAPEMISRSFGVISSKSDVYSFGMLLLEMAGGRRNADPNAANTSKAYYPS 440 S+ + GT Y++PE + +SD+YS G +L EM GR P +++ A Sbjct: 181 SQGVVGTAQYLSPEQARGE--TVDMRSDLYSAGCVLYEMLTGR---PPFTGDSAVA---- 231 Query: 439 WVYDRLIQQDHVGEIST 389 I HV E++T Sbjct: 232 ------IAYQHVSEVAT 242
>SKH1_SCHPO (Q9Y884) MAP kinase kinase skh1/pek1 (EC 2.7.12.2)| Length = 363 Score = 30.8 bits (68), Expect = 3.7 Identities = 18/38 (47%), Positives = 24/38 (63%) Frame = -3 Query: 604 GTIGYIAPEMISRSFGVISSKSDVYSFGMLLLEMAGGR 491 GT Y+APE IS IS SD++S G+ L+E+A R Sbjct: 241 GTSYYMAPERISGGSYTIS--SDIWSLGLTLMEVALNR 276
>PHY1_CERPU (P25848) Light-sensor Protein kinase [Includes: Phytochrome; Protein| kinase (EC 2.7.11.1)] Length = 1307 Score = 30.4 bits (67), Expect = 4.9 Identities = 21/51 (41%), Positives = 28/51 (54%), Gaps = 13/51 (25%) Frame = -3 Query: 607 RGTIGYIAPEMISRSF----GVISS---------KSDVYSFGMLLLEMAGG 494 RGT ++APE+I+ + G IS KSDVYSFGM+ E+ G Sbjct: 1174 RGTNRWMAPEVINLGYESTEGEISFDGKVPKYPLKSDVYSFGMVCYEVLTG 1224
>KAPC_YEAST (P05986) cAMP-dependent protein kinase type 3 (EC 2.7.11.11) (PKA| 3) Length = 398 Score = 30.4 bits (67), Expect = 4.9 Identities = 17/39 (43%), Positives = 23/39 (58%) Frame = -3 Query: 610 LRGTIGYIAPEMISRSFGVISSKSDVYSFGMLLLEMAGG 494 L GT YIAPE++S + D +SFG+L+ EM G Sbjct: 243 LCGTPDYIAPEVVSTK--PYNKSVDWWSFGVLIYEMLAG 279
>FLT3_HUMAN (P36888) FL cytokine receptor precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor FLT3) (Stem cell tyrosine kinase 1) (STK-1) (CD135 antigen) Length = 993 Score = 30.4 bits (67), Expect = 4.9 Identities = 16/45 (35%), Positives = 29/45 (64%) Frame = -3 Query: 637 DTSFVPSRALRGTIGYIAPEMISRSFGVISSKSDVYSFGMLLLEM 503 D+++V R + ++APE + G+ + KSDV+S+G+LL E+ Sbjct: 839 DSNYVVRGNARLPVKWMAPESLFE--GIYTIKSDVWSYGILLWEI 881
>ICL1_KLULA (Q6CWQ4) Spindle assembly checkpoint kinase (EC 2.7.11.1) (Aurora| kinase) Length = 361 Score = 30.4 bits (67), Expect = 4.9 Identities = 17/42 (40%), Positives = 28/42 (66%), Gaps = 1/42 (2%) Frame = -3 Query: 616 RALRGTIGYIAPEMI-SRSFGVISSKSDVYSFGMLLLEMAGG 494 + L GTI Y++PE+I SR + ++K DV++ G+L E+ G Sbjct: 255 KTLCGTIDYLSPELIKSREY---NNKVDVWALGVLTYELLVG 293
>GRK4_RAT (P70507) G protein-coupled receptor kinase 4 (EC 2.7.11.16) (G| protein-coupled receptor kinase GRK4) Length = 575 Score = 30.4 bits (67), Expect = 4.9 Identities = 16/37 (43%), Positives = 21/37 (56%) Frame = -3 Query: 604 GTIGYIAPEMISRSFGVISSKSDVYSFGMLLLEMAGG 494 GT+GY+APE+IS S D + G L+ EM G Sbjct: 347 GTVGYMAPEIISHEKYTFS--PDWWGLGCLIYEMIAG 381
>RAF1_CHICK (P05625) RAF proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (RAF-1) (C-RAF) (MIL proto-oncogene serine/threonine-protein kinase) (C-MIL) Length = 647 Score = 30.4 bits (67), Expect = 4.9 Identities = 16/38 (42%), Positives = 26/38 (68%), Gaps = 1/38 (2%) Frame = -3 Query: 604 GTIGYIAPEMIS-RSFGVISSKSDVYSFGMLLLEMAGG 494 G+I ++APE+I + S +SDVYS+G++L E+ G Sbjct: 507 GSILWMAPEVIRMQDSNPFSFQSDVYSYGIVLYELMTG 544 Database: uniprot_sprot.fasta Posted date: May 25, 2006 5:36 PM Number of letters in database: 80,573,946 Number of sequences in database: 219,361 Lambda K H 0.318 0.135 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 96,442,753 Number of Sequences: 219361 Number of extensions: 1965064 Number of successful extensions: 5560 Number of sequences better than 10.0: 324 Number of HSP's better than 10.0 without gapping: 5349 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 5526 length of database: 80,573,946 effective HSP length: 108 effective length of database: 56,882,958 effective search space used: 6257125380 frameshift window, decay const: 50, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
