>MCE1_SCHPO (P40997) mRNA capping enzyme alpha subunit (mRNA|
           guanylyltransferase) (EC 2.7.7.50) (GTP--RNA
           guanylyltransferase) (GTase)
          Length = 402

 Score = 59.7 bits (143), Expect = 6e-09
 Identities = 45/154 (29%), Positives = 77/154 (50%), Gaps = 17/154 (11%)
 Frame = -3

Query: 586 DDPYVNRTHEGLLKWKYPEMNSVDFLF-------ETGSENRQLVFLYERG---KKKLMDG 437
           + PYV+ T + LLKWK  EMN++DF+        E G  +   +  ++ G    + +   
Sbjct: 227 ETPYVSGTDQSLLKWKPKEMNTIDFMLKLEFAQPEEGDIDYSAMPEFQLGVWEGRNMYSF 286

Query: 436 TRIVFPEDVEQSS-------VSGKIVECSWNKQEDCWFCMRIRADKSTPNDINTYRKVMR 278
              ++ ++ E          +S +IVEC +   E+ W  +R R DK   N I+T + V++
Sbjct: 287 FAFMYVDEKEWEKLKSFNVPLSERIVEC-YLDDENRWRFLRFRDDKRDANHISTVKSVLQ 345

Query: 277 SITDNITEDKLLAEMNEISSLPMYADRKAHADRK 176
           SI D ++++ LL EM  I        R+A+ +RK
Sbjct: 346 SIEDGVSKEDLLKEMPII--------REAYYNRK 371

>MCE1_HUMAN (O60942) mRNA capping enzyme (HCE) (HCAP1) [Includes:|
           Polynucleotide 5'-triphosphatase (EC 3.1.3.33) (mRNA
           5'-triphosphatase) (TPase); mRNA guanylyltransferase (EC
           2.7.7.50) (GTP--RNA guanylyltransferase) (GTase)]
          Length = 597

 Score = 58.9 bits (141), Expect = 1e-08
 Identities = 40/132 (30%), Positives = 63/132 (47%), Gaps = 6/132 (4%)
 Frame = -3

Query: 559 EGLLKWKYPEMNSVDF---LFETGSEN---RQLVFLYERGKKKLMDGTRIVFPEDVEQSS 398
           + +LKWK P +NSVDF   +   G E    + +  LY  G ++     ++      E   
Sbjct: 454 DDILKWKPPSLNSVDFRLKITRMGGEGLLPQNVGLLYVGGYERPFAQIKVT----KELKQ 509

Query: 397 VSGKIVECSWNKQEDCWFCMRIRADKSTPNDINTYRKVMRSITDNITEDKLLAEMNEISS 218
              KI+EC +  + + W  MR R DKS PN  NT   V  SI++ +T++ L   ++  ++
Sbjct: 510 YDNKIIECKF--ENNSWVFMRQRTDKSFPNAYNTAMAVCNSISNPVTKEMLFEFIDRCTA 567

Query: 217 LPMYADRKAHAD 182
                 RK H D
Sbjct: 568 ASQGQKRKHHLD 579

>MCE1_YARLI (Q6C783) mRNA capping enzyme alpha subunit (mRNA|
           guanylyltransferase) (EC 2.7.7.50) (GTP--RNA
           guanylyltransferase) (GTase)
          Length = 391

 Score = 56.2 bits (134), Expect = 7e-08
 Identities = 55/179 (30%), Positives = 79/179 (44%), Gaps = 33/179 (18%)
 Frame = -3

Query: 586 DDPYVNRTHEGLLKWKYPEMNSVDFLF--------ETGSEN-------RQLVFLYERGKK 452
           D PYV+ T E +LKWK  + NSVDFL         +T  E+        ++  L   G+ 
Sbjct: 218 DHPYVSGTDERILKWKKQDENSVDFLMTMKFPIFEDTNGESWTDYDAKPEITLLVWTGR- 276

Query: 451 KLMDGTR---IVFPEDVE-------QSSVSGKIVECSWNKQEDCWFCMRIRADKSTPNDI 302
              DG+R    ++  D E       +  +  ++VEC  + ++  W  +R R DK+  N I
Sbjct: 277 ---DGSRPYGELYLTDEEWDNLKALEEPLEERVVECIKDDKKR-WRYLRFRDDKTNANYI 332

Query: 301 NTYRKVMRSITDNITEDKLLAEMNEISSL-------PMYADRK-AHADRKAHAEKMAHQ 149
            T  KV+ SI D ++E  LL    +I  L       P   DRK    D   H  K A Q
Sbjct: 333 TTVEKVIDSIDDPVSEKNLLDAAPKIKELWKERNRRPRDEDRKRVGGDDHDHGAKRARQ 391



 Score = 31.6 bits (70), Expect = 1.8
 Identities = 13/34 (38%), Positives = 22/34 (64%)
 Frame = -1

Query: 261 LLKTSSWPR*MKSVAFRCMPIGKLMLTGRPMPRR 160
           L+ T + PR +  + F C+   K++LTGRP+ +R
Sbjct: 121 LVLTKAEPRSLHFLMFDCLACNKILLTGRPLDKR 154

>MCE1_MOUSE (O55236) mRNA capping enzyme (HCE) (MCE1) [Includes: Polynucleotide|
           5'-triphosphatase (EC 3.1.3.33) (mRNA 5'-triphosphatase)
           (TPase); mRNA guanylyltransferase (EC 2.7.7.50)
           (GTP--RNA guanylyltransferase) (GTase)]
          Length = 597

 Score = 54.7 bits (130), Expect = 2e-07
 Identities = 39/132 (29%), Positives = 62/132 (46%), Gaps = 6/132 (4%)
 Frame = -3

Query: 559 EGLLKWKYPEMNSVDF---LFETGSEN---RQLVFLYERGKKKLMDGTRIVFPEDVEQSS 398
           + +LKWK P +NSVDF   +   G E    + +  LY  G ++     ++      E   
Sbjct: 454 DDILKWKPPSLNSVDFRLKITRMGGEGLLPQNVGLLYVGGYERPFAQIKVT----KELKQ 509

Query: 397 VSGKIVECSWNKQEDCWFCMRIRADKSTPNDINTYRKVMRSITDNITEDKLLAEMNEISS 218
              KI+EC +  + + W  MR R DKS PN  NT   V  SI++ +T++ L   ++  ++
Sbjct: 510 YDNKIIECKF--ENNSWVFMRQRIDKSFPNAYNTAMAVCNSISNPVTKEMLFEFIDRCAA 567

Query: 217 LPMYADRKAHAD 182
                 RK   D
Sbjct: 568 AAQGQKRKYPLD 579

>MCE1_CANAL (P78587) mRNA capping enzyme alpha subunit (mRNA|
           guanylyltransferase) (EC 2.7.7.50) (GTP--RNA
           guanylyltransferase) (GTase)
          Length = 449

 Score = 48.5 bits (114), Expect = 1e-05
 Identities = 46/166 (27%), Positives = 72/166 (43%), Gaps = 29/166 (17%)
 Frame = -3

Query: 586 DDPYVNRTHEGLLKWKYPEMNSVDFLFETGSENRQLVFLYERG---------------KK 452
           + PYV  T + LLKWK  E N+VDF  E      Q   L ER                K 
Sbjct: 228 ETPYVFGTDQTLLKWKPAEENTVDFQLEFVFNEVQDPDLDERDPTSTYLDYDAKPNLIKL 287

Query: 451 KLMDGTRI--------VFPEDVE-----QSSVSGKIVECSWN-KQEDCWFCMRIRADKST 314
           ++  G+ +        +  +D E     +  + G+I EC  +  ++  W  +R R DKS 
Sbjct: 288 RVWQGSNVHTDFAKLDLSDDDWERLKALEQPLQGRIAECRQSTTKKGYWEMLRFRNDKSN 347

Query: 313 PNDINTYRKVMRSITDNITEDKLLAEMNEISSLPMYADRKAHADRK 176
            N I+   K++ SI D + E +++    +IS     A +K   DR+
Sbjct: 348 GNHISVVEKILVSIKDGVKEKEVIEWCPKISR----AWKKRENDRR 389

>MCE1_CANGA (Q6FQ31) mRNA capping enzyme alpha subunit (mRNA|
           guanylyltransferase) (EC 2.7.7.50) (GTP--RNA
           guanylyltransferase) (GTase)
          Length = 449

 Score = 47.4 bits (111), Expect = 3e-05
 Identities = 22/63 (34%), Positives = 37/63 (58%)
 Frame = -3

Query: 406 QSSVSGKIVECSWNKQEDCWFCMRIRADKSTPNDINTYRKVMRSITDNITEDKLLAEMNE 227
           +  ++G+IVEC+ + +   W  +R R DK   N  +  +KV+ SI+D++T D L   + E
Sbjct: 340 EEPLNGRIVECTKDPETGSWTMLRFRDDKLNGNHTSVVQKVLESISDSVTIDDLAESVPE 399

Query: 226 ISS 218
           I S
Sbjct: 400 IKS 402

>MCE1_KLULA (Q6CWR0) mRNA capping enzyme alpha subunit (mRNA|
           guanylyltransferase) (EC 2.7.7.50) (GTP--RNA
           guanylyltransferase) (GTase)
          Length = 466

 Score = 46.6 bits (109), Expect = 5e-05
 Identities = 21/63 (33%), Positives = 39/63 (61%)
 Frame = -3

Query: 406 QSSVSGKIVECSWNKQEDCWFCMRIRADKSTPNDINTYRKVMRSITDNITEDKLLAEMNE 227
           +  ++G+IVECS +++   W  +R R DK   N ++  +KV+ SI D+++ D L   ++E
Sbjct: 341 EEPLNGRIVECSKDQESGAWKLLRFRDDKLNGNHVSVVQKVLESIGDSVSLDDLEQVVDE 400

Query: 226 ISS 218
           + S
Sbjct: 401 MRS 403

>MCE1_CAEEL (Q17607) mRNA capping enzyme [Includes: Polynucleotide|
           5'-triphosphatase (EC 3.1.3.33) (mRNA 5'-triphosphatase)
           (TPase); mRNA guanylyltransferase (EC 2.7.7.50)
           (GTP--RNA guanylyltransferase) (GTase)]
          Length = 623

 Score = 43.9 bits (102), Expect = 4e-04
 Identities = 39/141 (27%), Positives = 62/141 (43%), Gaps = 9/141 (6%)
 Frame = -3

Query: 553 LLKWKYPEMNSVDFLFETGSENRQLVFLYERGK---KKLMD--GTRIVFPEDVEQSSVSG 389
           +LKWK P  NSVDFL +   + ++ +     G    + L D  GT               
Sbjct: 475 VLKWKPPSHNSVDFLLKVEKKCKEGMLPEWIGYLFVQNLSDPFGT---MKATATLKKYHN 531

Query: 388 KIVECSW----NKQEDCWFCMRIRADKSTPNDINTYRKVMRSITDNITEDKLLAEMNEIS 221
           KI+EC+       +   W  MR R DKS PN + T   V+ ++ + +TE  L+  +N   
Sbjct: 532 KIIECTLLVDNQGRPKEWKFMRERTDKSLPNGLRTAENVVETMVNPVTETYLIEYVNHAL 591

Query: 220 SLPMYADRKAHADRKAHAEKM 158
            +   A   AH   + H +++
Sbjct: 592 RVLKRA-AAAHRHHQIHQQQL 611

>MCE1_YEAST (Q01159) mRNA capping enzyme alpha subunit (mRNA|
           guanylyltransferase) (EC 2.7.7.50) (GTP--RNA
           guanylyltransferase) (GTase)
          Length = 459

 Score = 42.7 bits (99), Expect = 8e-04
 Identities = 18/54 (33%), Positives = 33/54 (61%)
 Frame = -3

Query: 406 QSSVSGKIVECSWNKQEDCWFCMRIRADKSTPNDINTYRKVMRSITDNITEDKL 245
           +  ++G+IVEC+ N++   W  +R R DK   N  +  +KV+ SI D+++ + L
Sbjct: 344 EQPLNGRIVECAKNQETGAWEMLRFRDDKLNGNHTSVVQKVLESINDSVSLEDL 397

>MCE1_ASHGO (Q755D0) mRNA capping enzyme alpha subunit (mRNA|
           guanylyltransferase) (EC 2.7.7.50) (GTP--RNA
           guanylyltransferase) (GTase)
          Length = 463

 Score = 40.0 bits (92), Expect = 0.005
 Identities = 17/54 (31%), Positives = 34/54 (62%)
 Frame = -3

Query: 406 QSSVSGKIVECSWNKQEDCWFCMRIRADKSTPNDINTYRKVMRSITDNITEDKL 245
           +  ++G+IVEC+ +++   W  +R R DK   N ++  +KV+ SI+D++  + L
Sbjct: 340 EQPLNGRIVECAKDQETGEWKFLRFRDDKLNGNHVSVVQKVLESISDSVKLEDL 393

>MCE_PBCV1 (Q84424) mRNA capping enzyme (mRNA guanylyltransferase) (EC|
           2.7.7.50) (GTP--RNA guanylyltransferase)
          Length = 330

 Score = 40.0 bits (92), Expect = 0.005
 Identities = 33/124 (26%), Positives = 56/124 (45%), Gaps = 9/124 (7%)
 Frame = -3

Query: 586 DDPYVNRTHEGLLKWKYPEMNSVDFLFETGSENRQLVFLYERGKKKLMDGTRIVFPEDVE 407
           D+P +   +  L K K    +++DF+  +                   DGT  +F  ++ 
Sbjct: 221 DEPVIYGRNFNLFKLKPGTHHTIDFIIMSE------------------DGTIGIFDPNLR 262

Query: 406 QSSVSGK---------IVECSWNKQEDCWFCMRIRADKSTPNDINTYRKVMRSITDNITE 254
           ++   GK         IVEC +   +  W  ++ R+DK+  ND  TY K + +I +NIT 
Sbjct: 263 KNVPVGKLDGYYNKGSIVECGF--ADGTWKYIQGRSDKNQANDRLTYEKTLLNIEENITI 320

Query: 253 DKLL 242
           D+LL
Sbjct: 321 DELL 324

>PTN22_MOUSE (P29352) Tyrosine-protein phosphatase non-receptor type 22 (EC|
           3.1.3.48) (Hematopoietic cell protein-tyrosine
           phosphatase 70Z-PEP)
          Length = 802

 Score = 31.2 bits (69), Expect = 2.4
 Identities = 15/28 (53%), Positives = 18/28 (64%)
 Frame = +3

Query: 369 QEHSTIFPETEDCSTSSGNTIRVPSISF 452
           Q  ST +PET + STSS  T+R P  SF
Sbjct: 714 QTSSTSYPETTENSTSSKQTLRTPGKSF 741

>Y474_MYCPN (P75310) Hypothetical protein MG328 homolog (P01_orf1033)|
          Length = 1033

 Score = 30.0 bits (66), Expect = 5.3
 Identities = 35/154 (22%), Positives = 62/154 (40%), Gaps = 10/154 (6%)
 Frame = -3

Query: 571 NRTHEGLLKWKYPEMNSVDFLFETGSENRQL--------VFLYERGKKKLMDGTRIVFPE 416
           NRT +  L+   PE N ++F+ E   E  Q         +  Y+   KK  +   ++   
Sbjct: 435 NRTLKQHLQNNLPEANQLNFVLEKQLEQLQQDKHSLTLQIEQYKFDSKKHQEQLALIPSL 494

Query: 415 DVEQSSVSGKIVECSWNKQEDCWFCMRIRADKSTPNDINTYRKVMRS--ITDNITEDKLL 242
             E +S+  +++      Q       R+   +   N + T  K +R   + D  T+ + L
Sbjct: 495 RSEINSLETEVISLKQTNQ-------RLSLIERENNFLKTEIKQLRETKLNDENTKYRNL 547

Query: 241 AEMNEISSLPMYADRKAHADRKAHAEKMAHQHRR 140
            +  E+    M AD  A      H + +AHQH +
Sbjct: 548 LKQYEL----MRADSDAKLKELEHEQHLAHQHHQ 577

>TSP3_BRARE (Q8JHW2) Thrombospondin-3 precursor (Thbs3)|
          Length = 962

 Score = 30.0 bits (66), Expect = 5.3
 Identities = 26/92 (28%), Positives = 47/92 (51%), Gaps = 4/92 (4%)
 Frame = -3

Query: 550  LKWKYPEMNSVDFLFETGSENRQLVFLYERG--KKKLMDGTRIVFPEDV--EQSSVSGKI 383
            L WK P   +V +L +T S   QL    + G  + KL +G+ +V   DV  + S   G++
Sbjct: 866  LLWKDPR--NVGWLDKT-SYRWQLSHRPQVGYIRVKLYEGSEMVADSDVVIDTSMRGGRL 922

Query: 382  VECSWNKQEDCWFCMRIRADKSTPNDINTYRK 287
                ++++   W  +R R + + P D +++RK
Sbjct: 923  GVFCFSQENIIWSNLRYRCNDTVPEDFSSHRK 954

>BT1A1_HUMAN (Q13410) Butyrophilin subfamily 1 member A1 precursor (BT)|
          Length = 526

 Score = 30.0 bits (66), Expect = 5.3
 Identities = 16/49 (32%), Positives = 26/49 (53%)
 Frame = -3

Query: 550 LKWKYPEMNSVDFLFETGSENRQLVFLYERGKKKLMDGTRIVFPEDVEQ 404
           LKWK   +++VD   +  + +  L FLYE  K   ++ +R   PE  E+
Sbjct: 293 LKWKKATLHAVDVTLDPDTAHPHL-FLYEDSKSVRLEDSRQKLPEKTER 340

>MQO_BLOFL (Q7VRS0) Probable malate:quinone oxidoreductase (EC 1.1.99.16)|
           (Malate dehydrogenase [acceptor]) (MQO)
          Length = 524

 Score = 29.3 bits (64), Expect = 9.0
 Identities = 18/61 (29%), Positives = 27/61 (44%)
 Frame = -3

Query: 571 NRTHEGLLKWKYPEMNSVDFLFETGSENRQLVFLYERGKKKLMDGTRIVFPEDVEQSSVS 392
           N      LK  YPE+NS D+      +  Q++    + +  L  GT IV   D   S++ 
Sbjct: 384 NHDRINALKEYYPEVNSKDWFLIQAGQRVQIIKKNNKNRGILQFGTEIVSSADGSLSALL 443

Query: 391 G 389
           G
Sbjct: 444 G 444

>ATG9_MAGGR (Q51WZ9) Autophagy-related protein 9|
          Length = 917

 Score = 29.3 bits (64), Expect = 9.0
 Identities = 11/21 (52%), Positives = 14/21 (66%)
 Frame = -3

Query: 568 RTHEGLLKWKYPEMNSVDFLF 506
           RT+  L KWK+ E N +D LF
Sbjct: 483 RTYNSLAKWKFREFNELDHLF 503

>BT1A1_BOVIN (P18892) Butyrophilin subfamily 1 member A1 precursor (BT)|
          Length = 526

 Score = 29.3 bits (64), Expect = 9.0
 Identities = 16/49 (32%), Positives = 26/49 (53%)
 Frame = -3

Query: 550 LKWKYPEMNSVDFLFETGSENRQLVFLYERGKKKLMDGTRIVFPEDVEQ 404
           LKWK   +++VD   +  + +  L FLYE  K   ++ +R   PE  E+
Sbjct: 293 LKWKRATLHAVDVTLDPDTAHPHL-FLYEDSKSVRLEDSRQKLPEKPER 340


  Database: uniprot_sprot.fasta
    Posted date:  May 25, 2006  5:36 PM
  Number of letters in database: 80,573,946
  Number of sequences in database:  219,361
  
Lambda     K      H
   0.318    0.135    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 81,582,237
Number of Sequences: 219361
Number of extensions: 1620087
Number of successful extensions: 4132
Number of sequences better than 10.0: 18
Number of HSP's better than 10.0 without gapping: 4023
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4128
length of database: 80,573,946
effective HSP length: 106
effective length of database: 57,321,680
effective search space used: 5216272880
frameshift window, decay const: 50,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)