ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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| Clone Name | rbasd14o13 |
|---|---|
| Clone Library Name | barley_pub |
>RLCK7_ARATH (Q9LQQ8) Probable serine/threonine-protein kinase RLCKVII (EC| 2.7.11.1) Length = 423 Score = 111 bits (278), Expect = 2e-24 Identities = 53/105 (50%), Positives = 71/105 (67%) Frame = -3 Query: 652 YSAPEFAMSGTYTVKSDVYSFGVVMLELLTGRKPLDRSRERSEQSLVGWATPQLHDIDAL 473 Y AP++AM+G T KSD+YSFGVV+LEL+TGRK +D ++ R +Q+LVGWA P D Sbjct: 273 YCAPDYAMTGQLTFKSDIYSFGVVLLELITGRKAIDNTKTRKDQNLVGWARPLFKDRRNF 332 Query: 472 AKMVDPAMDGMYPAKSLSRFADIIALSVQPEPEFRPPISEVVQQL 338 KMVDP + G YP + L + I A+ VQ +P RP +S+VV L Sbjct: 333 PKMVDPLLQGQYPVRGLYQALAISAMCVQEQPTMRPVVSDVVLAL 377
>PBS1_ARATH (Q9FE20) Serine/threonine-protein kinase PBS1 (EC 2.7.11.1)| (AvrPphB susceptible protein 1) Length = 456 Score = 102 bits (255), Expect = 8e-22 Identities = 56/141 (39%), Positives = 81/141 (57%), Gaps = 4/141 (2%) Frame = -3 Query: 652 YSAPEFAMSGTYTVKSDVYSFGVVMLELLTGRKPLDRSRERSEQSLVGWATPQLHDIDAL 473 Y APE+AM+G TVKSDVYSFGVV LEL+TGRK +D EQ+LV WA P +D Sbjct: 256 YCAPEYAMTGQLTVKSDVYSFGVVFLELITGRKAIDSEMPHGEQNLVAWARPLFNDRRKF 315 Query: 472 AKMVDPAMDGMYPAKSLSRFADIIALSVQPEPEFRPPISEVVQQLVRLMQRA----SMLR 305 K+ DP + G +P ++L + + ++ +Q + RP I++VV L L +A Sbjct: 316 IKLADPRLKGRFPTRALYQALAVASMCIQEQAATRPLIADVVTALSYLANQAYDPSKDDS 375 Query: 304 RQSGDDLGSSYRAPEREGGAS 242 R++ D+ G+ +GG S Sbjct: 376 RRNRDERGARLITRNDDGGGS 396
>NAK_ARATH (P43293) Probable serine/threonine-protein kinase NAK (EC 2.7.11.1)| Length = 389 Score = 84.7 bits (208), Expect = 2e-16 Identities = 41/108 (37%), Positives = 68/108 (62%) Frame = -3 Query: 652 YSAPEFAMSGTYTVKSDVYSFGVVMLELLTGRKPLDRSRERSEQSLVGWATPQLHDIDAL 473 Y+APE+ +G +VKSDVYSFGVV+LELL+GR+ +D+++ E +LV WA P L + L Sbjct: 246 YAAPEYLATGHLSVKSDVYSFGVVLLELLSGRRAIDKNQPVGEHNLVDWARPYLTNKRRL 305 Query: 472 AKMVDPAMDGMYPAKSLSRFADIIALSVQPEPEFRPPISEVVQQLVRL 329 +++DP + G Y + A + + + + RP ++E+V+ + L Sbjct: 306 LRVMDPRLQGQYSLTRALKIAVLALDCISIDAKSRPTMNEIVKTMEEL 353
>APK1A_ARATH (Q06548) Protein kinase APK1A, chloroplast precursor (EC 2.7.11.1)| Length = 410 Score = 84.0 bits (206), Expect = 4e-16 Identities = 42/105 (40%), Positives = 65/105 (61%) Frame = -3 Query: 652 YSAPEFAMSGTYTVKSDVYSFGVVMLELLTGRKPLDRSRERSEQSLVGWATPQLHDIDAL 473 Y+APE+ +G T KSDVYSFGVV+LELL+GR+ +D++R E++LV WA P L + + Sbjct: 246 YAAPEYLATGHLTTKSDVYSFGVVLLELLSGRRAVDKNRPSGERNLVEWAKPYLVNKRKI 305 Query: 472 AKMVDPAMDGMYPAKSLSRFADIIALSVQPEPEFRPPISEVVQQL 338 +++D + Y + + A + + E + RP +SEVV L Sbjct: 306 FRVIDNRLQDQYSMEEACKVATLSLRCLTTEIKLRPNMSEVVSHL 350
>CX32_ARATH (P27450) Probable serine/threonine-protein kinase Cx32, chloroplast| precursor (EC 2.7.11.1) Length = 419 Score = 83.6 bits (205), Expect = 5e-16 Identities = 40/105 (38%), Positives = 65/105 (61%) Frame = -3 Query: 652 YSAPEFAMSGTYTVKSDVYSFGVVMLELLTGRKPLDRSRERSEQSLVGWATPQLHDIDAL 473 Y+APE+ +G VKSDV++FGVV+LE++TG + R R ++SLV W P+L + + Sbjct: 261 YAAPEYMATGHLYVKSDVFAFGVVLLEIMTGLTAHNTKRPRGQESLVDWLRPELSNKHRV 320 Query: 472 AKMVDPAMDGMYPAKSLSRFADIIALSVQPEPEFRPPISEVVQQL 338 +++D + G Y K + A I ++P+P+ RP + EVV+ L Sbjct: 321 KQIMDKGIKGQYTTKVATEMARITLSCIEPDPKNRPHMKEVVEVL 365
>APK1B_ARATH (P46573) Protein kinase APK1B, chloroplast precursor (EC 2.7.11.1)| Length = 412 Score = 81.3 bits (199), Expect = 2e-15 Identities = 41/105 (39%), Positives = 64/105 (60%) Frame = -3 Query: 652 YSAPEFAMSGTYTVKSDVYSFGVVMLELLTGRKPLDRSRERSEQSLVGWATPQLHDIDAL 473 Y+APE+ +G T KSDVYS+GVV+LE+L+GR+ +D++R EQ LV WA P L + L Sbjct: 247 YAAPEYLATGHLTTKSDVYSYGVVLLEVLSGRRAVDKNRPPGEQKLVEWARPLLANKRKL 306 Query: 472 AKMVDPAMDGMYPAKSLSRFADIIALSVQPEPEFRPPISEVVQQL 338 +++D + Y + + A + + E + RP ++EVV L Sbjct: 307 FRVIDNRLQDQYSMEEACKVATLALRCLTFEIKLRPNMNEVVSHL 351
>NORK_PEA (Q8LKZ1) Nodulation receptor kinase precursor (EC 2.7.11.1)| Length = 924 Score = 80.5 bits (197), Expect = 4e-15 Identities = 46/130 (35%), Positives = 78/130 (60%), Gaps = 2/130 (1%) Frame = -3 Query: 652 YSAPEFAMSGTYTVKSDVYSFGVVMLELLTGRKPLDRSRERSEQSLVGWATPQLHDIDAL 473 Y PE+ + + KSDV+SFGVV+LE+++GR+PL+ R R E SLV WA P + + Sbjct: 764 YLDPEYYKTQQLSEKSDVFSFGVVLLEIVSGREPLNIKRPRVEWSLVEWAKPYIR-ASKV 822 Query: 472 AKMVDPAMDGMYPAKSLSRFADIIALSVQPEPEFRPPISEVVQQL--VRLMQRASMLRRQ 299 ++VDP + G Y A++L R ++ ++P +RP + ++V++L +++ + + Sbjct: 823 DEIVDPGIKGGYHAEALWRVVEVALQCLEPYSTYRPCMVDIVRELEDALIIENNASEYMK 882 Query: 298 SGDDLGSSYR 269 S D LG S R Sbjct: 883 SIDSLGGSNR 892
>NORK_MEDTR (Q8L4H4) Nodulation receptor kinase precursor (EC 2.7.11.1) (Does not| make infections protein 2) (Symbiosis receptor-like kinase) (MtSYMRK) Length = 925 Score = 80.5 bits (197), Expect = 4e-15 Identities = 46/130 (35%), Positives = 78/130 (60%), Gaps = 2/130 (1%) Frame = -3 Query: 652 YSAPEFAMSGTYTVKSDVYSFGVVMLELLTGRKPLDRSRERSEQSLVGWATPQLHDIDAL 473 Y PE+ + + KSDV+SFGVV+LE+++GR+PL+ R R E SLV WA P + + Sbjct: 765 YLDPEYYKTQQLSEKSDVFSFGVVLLEIVSGREPLNIKRPRIEWSLVEWAKPYIR-ASKV 823 Query: 472 AKMVDPAMDGMYPAKSLSRFADIIALSVQPEPEFRPPISEVVQQL--VRLMQRASMLRRQ 299 ++VDP + G Y A++L R ++ ++P +RP + ++V++L +++ + + Sbjct: 824 DEIVDPGIKGGYHAEALWRVVEVALQCLEPYSTYRPCMVDIVRELEDALIIENNASEYMK 883 Query: 298 SGDDLGSSYR 269 S D LG S R Sbjct: 884 SIDSLGGSNR 893
>PSKR_ARATH (Q9ZVR7) Putative phytosulfokine receptor precursor (EC 2.7.11.1)| (Phytosulfokine LRR receptor kinase) Length = 1008 Score = 68.9 bits (167), Expect = 1e-11 Identities = 36/107 (33%), Positives = 57/107 (53%) Frame = -3 Query: 658 LEYSAPEFAMSGTYTVKSDVYSFGVVMLELLTGRKPLDRSRERSEQSLVGWATPQLHDID 479 L Y PE+ + T K DVYSFGVV+LELLT ++P+D + + + L+ W H+ Sbjct: 900 LGYIPPEYGQASVATYKGDVYSFGVVLLELLTDKRPVDMCKPKGCRDLISWVVKMKHESR 959 Query: 478 ALAKMVDPAMDGMYPAKSLSRFADIIALSVQPEPEFRPPISEVVQQL 338 A +++ DP + K + R +I L + P+ RP ++V L Sbjct: 960 A-SEVFDPLIYSKENDKEMFRVLEIACLCLSENPKQRPTTQQLVSWL 1005
>PSKR_DAUCA (Q8LPB4) Phytosulfokine receptor precursor (EC 2.7.11.1)| (Phytosulfokine LRR receptor kinase) Length = 1021 Score = 65.1 bits (157), Expect = 2e-10 Identities = 36/107 (33%), Positives = 56/107 (52%) Frame = -3 Query: 658 LEYSAPEFAMSGTYTVKSDVYSFGVVMLELLTGRKPLDRSRERSEQSLVGWATPQLHDID 479 L Y PE+ + T K DVYSFGVV+LELLTGR+P+D + R + L+ W Q+ Sbjct: 909 LGYIPPEYGQASVATYKGDVYSFGVVLLELLTGRRPMDVCKPRGSRDLISWVL-QMKTEK 967 Query: 478 ALAKMVDPAMDGMYPAKSLSRFADIIALSVQPEPEFRPPISEVVQQL 338 +++ DP + A+ + +I + P+ RP ++V L Sbjct: 968 RESEIFDPFIYDKDHAEEMLLVLEIACRCLGENPKTRPTTQQLVSWL 1014
>RPK1_IPONI (P93194) Receptor-like protein kinase precursor (EC 2.7.11.1)| Length = 1109 Score = 64.7 bits (156), Expect = 2e-10 Identities = 42/125 (33%), Positives = 72/125 (57%), Gaps = 6/125 (4%) Frame = -3 Query: 652 YSAPEFAMSGTYTVKSDVYSFGVVMLELLTGRKPLDRSRERSEQSLVGWATPQLHDIDAL 473 Y APE A + + +SDVYS+GVV+LEL+T +K LD S E +VGW + Sbjct: 985 YMAPENAFTTVKSRESDVYSYGVVLLELITRKKALDPS-FNGETDIVGWVRSVWTQTGEI 1043 Query: 472 AKMVDPA-MDGMYPAKSLSRFADIIALSV---QPEPEFRPPISEVVQQLVR--LMQRASM 311 K+VDP+ +D + + + + + ++L++ + E + RP + +VV+QL R + +S Sbjct: 1044 QKIVDPSLLDELIDSSVMEQVTEALSLALRCAEKEVDKRPTMRDVVKQLTRWSIRSYSSS 1103 Query: 310 LRRQS 296 +R +S Sbjct: 1104 VRNKS 1108
>TMK1_ARATH (P43298) Putative receptor protein kinase TMK1 precursor (EC| 2.7.11.1) Length = 942 Score = 64.7 bits (156), Expect = 2e-10 Identities = 40/112 (35%), Positives = 58/112 (51%), Gaps = 2/112 (1%) Frame = -3 Query: 652 YSAPEFAMSGTYTVKSDVYSFGVVMLELLTGRKPLDRSRERSEQSLVGWATPQLHDIDA- 476 Y APE+A++G T K DVYSFGV+++EL+TGRK LD S+ LV W + +A Sbjct: 759 YLAPEYAVTGRVTTKVDVYSFGVILMELITGRKSLDESQPEESIHLVSWFKRMYINKEAS 818 Query: 475 LAKMVDPAMD-GMYPAKSLSRFADIIALSVQPEPEFRPPISEVVQQLVRLMQ 323 K +D +D S+ A++ EP RP + V L L++ Sbjct: 819 FKKAIDTTIDLDEETLASVHTVAELAGHCCAREPYQRPDMGHAVNILSSLVE 870
>EXS_ARATH (Q9LYN8) Leucine-rich repeat receptor protein kinase EXS precursor| (EC 2.7.11.1) (Extra sporogenous cells protein) (EXCESS MICROSPOROCYTES1 protein) Length = 1192 Score = 64.3 bits (155), Expect = 3e-10 Identities = 38/106 (35%), Positives = 59/106 (55%), Gaps = 1/106 (0%) Frame = -3 Query: 652 YSAPEFAMSGTYTVKSDVYSFGVVMLELLTGRKPLDRSRERSE-QSLVGWATPQLHDIDA 476 Y PE+ S T K DVYSFGV++LEL+TG++P + SE +LVGWA +++ A Sbjct: 1085 YIPPEYGQSARATTKGDVYSFGVILLELVTGKEPTGPDFKESEGGNLVGWAIQKINQGKA 1144 Query: 475 LAKMVDPAMDGMYPAKSLSRFADIIALSVQPEPEFRPPISEVVQQL 338 + ++DP + + S R I L + P RP + +V++ L Sbjct: 1145 V-DVIDPLLVSVALKNSQLRLLQIAMLCLAETPAKRPNMLDVLKAL 1189
>CRI4_MAIZE (O24585) Putative receptor protein kinase CRINKLY4 precursor (EC| 2.7.11.1) Length = 901 Score = 63.2 bits (152), Expect = 7e-10 Identities = 39/107 (36%), Positives = 58/107 (54%) Frame = -3 Query: 658 LEYSAPEFAMSGTYTVKSDVYSFGVVMLELLTGRKPLDRSRERSEQSLVGWATPQLHDID 479 L Y PE+ T KSDVYSFGVV+LE+L+GRK +D E E ++V WA P + D Sbjct: 675 LGYLDPEYYRLHYLTTKSDVYSFGVVLLEILSGRKAIDMQFE--EGNIVEWAVPLIKAGD 732 Query: 478 ALAKMVDPAMDGMYPAKSLSRFADIIALSVQPEPEFRPPISEVVQQL 338 A ++DP + ++L + A + V+ + RP + +V L Sbjct: 733 IFA-ILDPVLSPPSDLEALKKIASVACKCVRMRGKDRPSMDKVTTAL 778
>CLV1_ARATH (Q9SYQ8) Receptor protein kinase CLAVATA1 precursor (EC 2.7.11.1)| Length = 980 Score = 62.8 bits (151), Expect = 9e-10 Identities = 42/111 (37%), Positives = 57/111 (51%), Gaps = 6/111 (5%) Frame = -3 Query: 652 YSAPEFAMSGTYTVKSDVYSFGVVMLELLTGRKPLDRSRERSEQSLVGWA------TPQL 491 Y APE+A + KSDVYSFGVV+LEL+ G+KP+ E + +V W Q Sbjct: 860 YIAPEYAYTLKVDEKSDVYSFGVVLLELIAGKKPVGEFGEGVD--IVRWVRNTEEEITQP 917 Query: 490 HDIDALAKMVDPAMDGMYPAKSLSRFADIIALSVQPEPEFRPPISEVVQQL 338 D + +VDP + G YP S+ I + V+ E RP + EVV L Sbjct: 918 SDAAIVVAIVDPRLTG-YPLTSVIHVFKIAMMCVEEEAAARPTMREVVHML 967
>BRL3_ARATH (Q9LJF3) Serine/threonine-protein kinase BRI1-like 3 precursor (EC| 2.7.11.1) (BRASSINOSTEROID INSENSITIVE 1-like protein 3) Length = 1164 Score = 62.0 bits (149), Expect = 2e-09 Identities = 38/111 (34%), Positives = 59/111 (53%), Gaps = 1/111 (0%) Frame = -3 Query: 652 YSAPEFAMSGTYTVKSDVYSFGVVMLELLTGRKPLDRSRERSEQSLVGWATPQLHDIDAL 473 Y PE+ S T K DVYS+GV++LELL+G+KP+D + +LVGWA QL+ Sbjct: 1028 YVPPEYYQSFRCTAKGDVYSYGVILLELLSGKKPIDPEEFGEDNNLVGWA-KQLYREKRG 1086 Query: 472 AKMVDPAM-DGMYPAKSLSRFADIIALSVQPEPEFRPPISEVVQQLVRLMQ 323 A+++DP + L + I + + P RP + +V+ L+Q Sbjct: 1087 AEILDPELVTDKSGDVELLHYLKIASQCLDDRPFKRPTMIQVMTMFKELVQ 1137
>BAK1_ARATH (Q94F62) BRASSINOSTEROID INSENSITIVE 1-associated receptor kinase 1| precursor (EC 2.7.11.1) (BRI1-associated receptor kinase 1) (Somatic embryogenesis receptor-like kinase 3) Length = 615 Score = 60.8 bits (146), Expect = 3e-09 Identities = 34/105 (32%), Positives = 58/105 (55%), Gaps = 2/105 (1%) Frame = -3 Query: 646 APEFAMSGTYTVKSDVYSFGVVMLELLTGRKPLDRSRERSEQS--LVGWATPQLHDIDAL 473 APE+ +G + K+DV+ +GV++LEL+TG++ D +R ++ L+ W L + L Sbjct: 460 APEYLSTGKSSEKTDVFGYGVMLLELITGQRAFDLARLANDDDVMLLDWVKGLLKE-KKL 518 Query: 472 AKMVDPAMDGMYPAKSLSRFADIIALSVQPEPEFRPPISEVVQQL 338 +VD + G Y + + + + L Q P RP +SEVV+ L Sbjct: 519 EALVDVDLQGNYKDEEVEQLIQVALLCTQSSPMERPKMSEVVRML 563
>RLK5_ARATH (P47735) Receptor-like protein kinase 5 precursor (EC 2.7.11.1)| Length = 999 Score = 60.1 bits (144), Expect = 6e-09 Identities = 38/105 (36%), Positives = 57/105 (54%) Frame = -3 Query: 652 YSAPEFAMSGTYTVKSDVYSFGVVMLELLTGRKPLDRSRERSEQSLVGWATPQLHDIDAL 473 Y APE+ + KSD+YSFGVV+LEL+TG++P D E ++ + W L D L Sbjct: 864 YIAPEYVYTLRVNEKSDIYSFGVVLLELVTGKQPTD--SELGDKDMAKWVCTAL-DKCGL 920 Query: 472 AKMVDPAMDGMYPAKSLSRFADIIALSVQPEPEFRPPISEVVQQL 338 ++DP +D + + +S+ I L P P RP + +VV L Sbjct: 921 EPVIDPKLDLKF-KEEISKVIHIGLLCTSPLPLNRPSMRKVVIML 964
>BRL1_ARATH (Q9ZWC8) Serine/threonine-protein kinase BRI1-like 1 precursor (EC| 2.7.11.1) (BRASSINOSTEROID INSENSITIVE 1-like protein 1) Length = 1166 Score = 59.7 bits (143), Expect = 8e-09 Identities = 30/68 (44%), Positives = 44/68 (64%) Frame = -3 Query: 652 YSAPEFAMSGTYTVKSDVYSFGVVMLELLTGRKPLDRSRERSEQSLVGWATPQLHDIDAL 473 Y PE+ S T K DVYS+GV++LELL+G+KP+D + +LVGWA QL+ Sbjct: 1030 YVPPEYYQSFRCTAKGDVYSYGVILLELLSGKKPIDPGEFGEDNNLVGWA-KQLYREKRG 1088 Query: 472 AKMVDPAM 449 A+++DP + Sbjct: 1089 AEILDPEL 1096
>BRI1_ARATH (O22476) BRASSINOSTEROID INSENSITIVE 1 precursor (EC 2.7.11.1)| (AtBRI1) (Brassinosteroid LRR receptor kinase) Length = 1196 Score = 57.8 bits (138), Expect = 3e-08 Identities = 44/138 (31%), Positives = 73/138 (52%), Gaps = 1/138 (0%) Frame = -3 Query: 652 YSAPEFAMSGTYTVKSDVYSFGVVMLELLTGRKPLDRSRERSEQSLVGWATPQLHDIDAL 473 Y PE+ S + K DVYS+GVV+LELLTG++P D S + + +LVGW + H + Sbjct: 1052 YVPPEYYQSFRCSTKGDVYSYGVVLLELLTGKRPTD-SPDFGDNNLVGWV--KQHAKLRI 1108 Query: 472 AKMVDPAMDGMYPAKSLSRFADI-IALSVQPEPEFRPPISEVVQQLVRLMQRASMLRRQS 296 + + DP + PA + + +A++ + +R P +V++M ++ S Sbjct: 1109 SDVFDPELMKEDPALEIELLQHLKVAVACLDDRAWRRP------TMVQVMAMFKEIQAGS 1162 Query: 295 GDDLGSSYRAPEREGGAS 242 G D S+ R+ E +GG S Sbjct: 1163 GIDSQSTIRSIE-DGGFS 1179
>BRL2_ARATH (Q9ZPS9) Serine/threonine-protein kinase BRI1-like 2 precursor (EC| 2.7.11.1) (BRASSINOSTEROID INSENSITIVE 1-like protein 2) (Protein VASCULAR HIGHWAY 1) Length = 1143 Score = 56.2 bits (134), Expect = 8e-08 Identities = 40/122 (32%), Positives = 60/122 (49%), Gaps = 14/122 (11%) Frame = -3 Query: 652 YSAPEFAMSGTYTVKSDVYSFGVVMLELLTGRKPLDRSRERSEQSLVGWAT--------P 497 Y PE+ S T K DVYS GVVMLE+L+G++P D+ E + +LVGW+ Sbjct: 1009 YVPPEYYQSFRCTAKGDVYSIGVVMLEILSGKRPTDK-EEFGDTNLVGWSKMKAREGKHM 1067 Query: 496 QLHDIDALAKMVDPAM------DGMYPAKSLSRFADIIALSVQPEPEFRPPISEVVQQLV 335 ++ D D L + ++ +G K + R+ +I V P RP + +VV L Sbjct: 1068 EVIDEDLLKEGSSESLNEKEGFEGGVIVKEMLRYLEIALRCVDDFPSKRPNMLQVVASLR 1127 Query: 334 RL 329 L Sbjct: 1128 EL 1129
>SRK6_BRAOE (Q09092) Putative serine/threonine-protein kinase receptor precursor| (EC 2.7.11.1) (S-receptor kinase) (SRK) Length = 849 Score = 53.1 bits (126), Expect = 7e-07 Identities = 35/109 (32%), Positives = 59/109 (54%), Gaps = 7/109 (6%) Frame = -3 Query: 652 YSAPEFAMSGTYTVKSDVYSFGVVMLELLTGRKPLDRSRERSEQSLVGWATPQLHDIDAL 473 Y +PE+AM G ++ KSDV+SFGV++LE+++G+K E L+ + + + AL Sbjct: 696 YMSPEYAMYGIFSEKSDVFSFGVIVLEIVSGKKNRGFYNLDYENDLLSYVWSRWKEGRAL 755 Query: 472 AKMVDP-------AMDGMYPAKSLSRFADIIALSVQPEPEFRPPISEVV 347 ++VDP + ++ + + + I L VQ E RP +S VV Sbjct: 756 -EIVDPVIVDSLSSQPSIFQPQEVLKCIQIGLLCVQELAEHRPAMSSVV 803
>BRI1_LYCPE (Q8L899) Systemin receptor SR160 precursor (EC 2.7.11.1)| (Brassinosteroid LRR receptor kinase) Length = 1207 Score = 51.6 bits (122), Expect = 2e-06 Identities = 25/49 (51%), Positives = 34/49 (69%) Frame = -3 Query: 652 YSAPEFAMSGTYTVKSDVYSFGVVMLELLTGRKPLDRSRERSEQSLVGW 506 Y PE+ S + K DVYS+GVV+LELLTG++P D S + + +LVGW Sbjct: 1057 YVPPEYYQSFRCSTKGDVYSYGVVLLELLTGKQPTD-SADFGDNNLVGW 1104
>BRI1_LYCES (Q8GUQ5) Brassinosteroid LRR receptor kinase precursor (EC 2.7.11.1)| (tBRI1) (Altered brassinolide sensitivity 1) (Systemin receptor SR160) Length = 1207 Score = 51.6 bits (122), Expect = 2e-06 Identities = 25/49 (51%), Positives = 34/49 (69%) Frame = -3 Query: 652 YSAPEFAMSGTYTVKSDVYSFGVVMLELLTGRKPLDRSRERSEQSLVGW 506 Y PE+ S + K DVYS+GVV+LELLTG++P D S + + +LVGW Sbjct: 1057 YVPPEYYQSFRCSTKGDVYSYGVVLLELLTGKQPTD-SADFGDNNLVGW 1104
>TMKL1_ARATH (P33543) Putative kinase-like protein TMKL1 precursor| Length = 674 Score = 50.1 bits (118), Expect = 6e-06 Identities = 37/114 (32%), Positives = 56/114 (49%), Gaps = 9/114 (7%) Frame = -3 Query: 652 YSAPEFAMSGTYTVKSDVYSFGVVMLELLTGRKPLDRSRERSE----QSLVGWA-----T 500 Y APE +SDVY+FG+++LE+L G+KP R +E SLV A T Sbjct: 542 YKAPELHKMKKCNPRSDVYAFGILLLEILMGKKPGKSGRNGNEFVDLPSLVKAAVLEETT 601 Query: 499 PQLHDIDALAKMVDPAMDGMYPAKSLSRFADIIALSVQPEPEFRPPISEVVQQL 338 ++ D++A+ + P +G+ A L+ P RP + EVV+QL Sbjct: 602 MEVFDLEAMKGIRSPMEEGLVHALKLAMGC------CAPVTTVRPSMEEVVKQL 649
>IRAK4_MOUSE (Q8R4K2) Interleukin-1 receptor-associated kinase 4 (EC 2.7.11.1)| (IRAK-4) Length = 459 Score = 48.9 bits (115), Expect = 1e-05 Identities = 39/109 (35%), Positives = 56/109 (51%) Frame = -3 Query: 652 YSAPEFAMSGTYTVKSDVYSFGVVMLELLTGRKPLDRSRERSEQSLVGWATPQLHDIDAL 473 Y APE A+ G T KSD+YSFGVV+LEL+TG +D +RE Q L+ + + Sbjct: 354 YMAPE-ALRGEITPKSDIYSFGVVLLELITGLAAVDENRE--PQLLLDIKEEIEDEEKTI 410 Query: 472 AKMVDPAMDGMYPAKSLSRFADIIALSVQPEPEFRPPISEVVQQLVRLM 326 D M PA S+ + + + RP I++ VQQL++ M Sbjct: 411 EDYTDEKMSDADPA-SVEAMYSAASQCLHEKKNRRPDIAK-VQQLLQEM 457
>YRK_CHICK (Q02977) Proto-oncogene tyrosine-protein kinase Yrk (EC 2.7.10.2)| (p60-Yrk) (Yes-related kinase) Length = 535 Score = 47.8 bits (112), Expect = 3e-05 Identities = 28/69 (40%), Positives = 42/69 (60%), Gaps = 10/69 (14%) Frame = -3 Query: 658 LEYSAPEFAMSGTYTVKSDVYSFGVVMLELLT-GRKPLD--RSRERSEQ-------SLVG 509 ++++APE A+ G +T+KSDV+SFG+++ EL+T GR P +RE EQ G Sbjct: 428 IKWTAPEAALFGKFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYRMQCPG 487 Query: 508 WATPQLHDI 482 P LHD+ Sbjct: 488 GCPPSLHDV 496
>M3K11_HUMAN (Q16584) Mitogen-activated protein kinase kinase kinase 11 (EC| 2.7.11.25) (Mixed lineage kinase 3) (Src-homology 3 domain-containing proline-rich kinase) Length = 847 Score = 47.8 bits (112), Expect = 3e-05 Identities = 40/136 (29%), Positives = 59/136 (43%), Gaps = 3/136 (2%) Frame = -3 Query: 652 YSAPEFAMSGTYTVKSDVYSFGVVMLELLTGRKPLDRSRERSEQSLVGWATPQLHDIDAL 473 + APE + T++ SDV+SFGV++ ELLTG P ID L Sbjct: 288 WMAPEVIKASTFSKGSDVWSFGVLLWELLTGEVP-------------------YRGIDCL 328 Query: 472 AKMVDPAMDGM---YPAKSLSRFADIIALSVQPEPEFRPPISEVVQQLVRLMQRASMLRR 302 A A++ + P+ FA ++A +P RP + ++QQL L A +LR Sbjct: 329 AVAYGVAVNKLTLPIPSTCPEPFAQLMADCWAQDPHRRPDFASILQQLEAL--EAQVLRE 386 Query: 301 QSGDDLGSSYRAPERE 254 D S +RE Sbjct: 387 MPRDSFHSMQEGWKRE 402
>YES_AVISY (P00527) Tyrosine-protein kinase transforming protein YES (EC| 2.7.10.2) (Fragment) Length = 528 Score = 47.0 bits (110), Expect = 5e-05 Identities = 30/78 (38%), Positives = 46/78 (58%), Gaps = 10/78 (12%) Frame = -3 Query: 658 LEYSAPEFAMSGTYTVKSDVYSFGVVMLELLT-GRKPLDR--SRERSEQSLVGWATP--- 497 ++++APE A+ G +T+KSDV+SFG+++ EL+T GR P +RE EQ G+ P Sbjct: 426 IKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMVNREVLEQVERGYRMPCPQ 485 Query: 496 ----QLHDIDALAKMVDP 455 LH++ L DP Sbjct: 486 GCPESLHELMKLCWKKDP 503
>YES_CHICK (P09324) Tyrosine-protein kinase Yes (EC 2.7.10.2) (p61-Yes)| Length = 540 Score = 47.0 bits (110), Expect = 5e-05 Identities = 30/78 (38%), Positives = 46/78 (58%), Gaps = 10/78 (12%) Frame = -3 Query: 658 LEYSAPEFAMSGTYTVKSDVYSFGVVMLELLT-GRKPLDR--SRERSEQSLVGWATP--- 497 ++++APE A+ G +T+KSDV+SFG+++ EL+T GR P +RE EQ G+ P Sbjct: 433 IKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMVNREVLEQVERGYRMPCPQ 492 Query: 496 ----QLHDIDALAKMVDP 455 LH++ L DP Sbjct: 493 GCPESLHELMKLCWKKDP 510
>SRC_AVIS2 (P15054) Tyrosine-protein kinase transforming protein Src (EC| 2.7.10.2) (p60-Src) (v-Src) (pp60v-src) Length = 586 Score = 47.0 bits (110), Expect = 5e-05 Identities = 37/111 (33%), Positives = 57/111 (51%), Gaps = 11/111 (9%) Frame = -3 Query: 658 LEYSAPEFAMSGTYTVKSDVYSFGVVMLELLT-GRKPLDR--SRERSEQSLVGWATP--- 497 ++++APE A+ G +T+KSDV+SFG+++ EL T GR P +RE +Q G+ P Sbjct: 425 IKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERGYRMPCPP 484 Query: 496 ----QLHDIDALAKMVDPAMDGMYPAKSLSRFADIIALSVQPE-PEFRPPI 359 LHD+ DP + + L F + S +P P +R PI Sbjct: 485 ECPESLHDLMCQCWRKDPEERPTF--EYLQAFLEDYFTSTEPPVPAWREPI 533
>FGR_MOUSE (P14234) Proto-oncogene tyrosine-protein kinase FGR (EC 2.7.10.2)| (P55-FGR) (C-FGR) Length = 517 Score = 46.6 bits (109), Expect = 7e-05 Identities = 30/78 (38%), Positives = 47/78 (60%), Gaps = 10/78 (12%) Frame = -3 Query: 658 LEYSAPEFAMSGTYTVKSDVYSFGVVMLELLT-GRKPLD--RSRERSEQSLVGWATP--- 497 ++++APE A+ G +TVKSDV+SFG+++ EL+T GR P +RE EQ G+ P Sbjct: 410 IKWTAPEAALFGRFTVKSDVWSFGILLTELITKGRVPYPGMNNREVLEQVEHGYHMPCPP 469 Query: 496 ----QLHDIDALAKMVDP 455 L+++ A +DP Sbjct: 470 GCPASLYEVMEQAWRLDP 487
>IRAK4_HUMAN (Q9NWZ3) Interleukin-1 receptor-associated kinase 4 (EC 2.7.11.1)| (IRAK-4) (NY-REN-64 antigen) Length = 460 Score = 46.6 bits (109), Expect = 7e-05 Identities = 23/40 (57%), Positives = 29/40 (72%) Frame = -3 Query: 652 YSAPEFAMSGTYTVKSDVYSFGVVMLELLTGRKPLDRSRE 533 Y APE A+ G T KSD+YSFGVV+LE++TG +D RE Sbjct: 354 YMAPE-ALRGEITPKSDIYSFGVVLLEIITGLPAVDEHRE 392
>FYN_XIPHE (P27446) Proto-oncogene tyrosine-protein kinase FYN (EC 2.7.10.2)| (P59-FYN) Length = 536 Score = 46.6 bits (109), Expect = 7e-05 Identities = 27/64 (42%), Positives = 41/64 (64%), Gaps = 3/64 (4%) Frame = -3 Query: 658 LEYSAPEFAMSGTYTVKSDVYSFGVVMLELLT-GRKPLD--RSRERSEQSLVGWATPQLH 488 ++++APE A+ G +T+KSDV+SFG+++ EL+T GR P +RE EQ G+ P Sbjct: 429 IKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYRMPCPQ 488 Query: 487 DIDA 476 D A Sbjct: 489 DCPA 492
>YES_HUMAN (P07947) Proto-oncogene tyrosine-protein kinase Yes (EC 2.7.10.2)| (p61-Yes) (c-Yes) Length = 542 Score = 45.8 bits (107), Expect = 1e-04 Identities = 30/78 (38%), Positives = 45/78 (57%), Gaps = 10/78 (12%) Frame = -3 Query: 658 LEYSAPEFAMSGTYTVKSDVYSFGVVMLELLT-GRKPLDR--SRERSEQSLVGWATP--- 497 ++++APE A+ G +T+KSDV+SFG++ EL+T GR P +RE EQ G+ P Sbjct: 435 IKWTAPEAALYGRFTIKSDVWSFGILQTELVTKGRVPYPGMVNREVLEQVERGYRMPCPQ 494 Query: 496 ----QLHDIDALAKMVDP 455 LH++ L DP Sbjct: 495 GCPESLHELMNLCWKKDP 512
>YES_MOUSE (Q04736) Proto-oncogene tyrosine-protein kinase Yes (EC 2.7.10.2)| (p61-Yes) (c-Yes) Length = 540 Score = 45.8 bits (107), Expect = 1e-04 Identities = 30/78 (38%), Positives = 45/78 (57%), Gaps = 10/78 (12%) Frame = -3 Query: 658 LEYSAPEFAMSGTYTVKSDVYSFGVVMLELLT-GRKPLDR--SRERSEQSLVGWATP--- 497 ++++APE A+ G +T+KSDV+SFG++ EL+T GR P +RE EQ G+ P Sbjct: 433 IKWTAPEAALYGRFTIKSDVWSFGILQTELVTKGRVPYPGMVNREVLEQVERGYRMPCPQ 492 Query: 496 ----QLHDIDALAKMVDP 455 LH++ L DP Sbjct: 493 GCPESLHELMNLCWKKDP 510
>FYN_XENLA (P13406) Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2)| (p59-Fyn) Length = 536 Score = 45.8 bits (107), Expect = 1e-04 Identities = 25/57 (43%), Positives = 39/57 (68%), Gaps = 3/57 (5%) Frame = -3 Query: 658 LEYSAPEFAMSGTYTVKSDVYSFGVVMLELLT-GRKPLD--RSRERSEQSLVGWATP 497 ++++APE A+ G +T+KSDV+SFG+++ EL+T GR P +RE EQ G+ P Sbjct: 429 IKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYRMP 485
>FYN_HUMAN (P06241) Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2)| (p59-Fyn) (Protooncogene Syn) (SLK) Length = 536 Score = 45.8 bits (107), Expect = 1e-04 Identities = 25/57 (43%), Positives = 39/57 (68%), Gaps = 3/57 (5%) Frame = -3 Query: 658 LEYSAPEFAMSGTYTVKSDVYSFGVVMLELLT-GRKPLD--RSRERSEQSLVGWATP 497 ++++APE A+ G +T+KSDV+SFG+++ EL+T GR P +RE EQ G+ P Sbjct: 429 IKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYRMP 485
>FYN_MOUSE (P39688) Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2)| (p59-Fyn) Length = 533 Score = 45.8 bits (107), Expect = 1e-04 Identities = 25/57 (43%), Positives = 39/57 (68%), Gaps = 3/57 (5%) Frame = -3 Query: 658 LEYSAPEFAMSGTYTVKSDVYSFGVVMLELLT-GRKPLD--RSRERSEQSLVGWATP 497 ++++APE A+ G +T+KSDV+SFG+++ EL+T GR P +RE EQ G+ P Sbjct: 426 IKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYRMP 482
>FYN_CHICK (Q05876) Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2)| (p59-Fyn) Length = 533 Score = 45.8 bits (107), Expect = 1e-04 Identities = 25/57 (43%), Positives = 39/57 (68%), Gaps = 3/57 (5%) Frame = -3 Query: 658 LEYSAPEFAMSGTYTVKSDVYSFGVVMLELLT-GRKPLD--RSRERSEQSLVGWATP 497 ++++APE A+ G +T+KSDV+SFG+++ EL+T GR P +RE EQ G+ P Sbjct: 426 IKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYRMP 482
>FGR_HUMAN (P09769) Proto-oncogene tyrosine-protein kinase FGR (EC 2.7.10.2)| (P55-FGR) (C-FGR) Length = 529 Score = 45.4 bits (106), Expect = 1e-04 Identities = 25/57 (43%), Positives = 38/57 (66%), Gaps = 3/57 (5%) Frame = -3 Query: 658 LEYSAPEFAMSGTYTVKSDVYSFGVVMLELLT-GRKPLD--RSRERSEQSLVGWATP 497 ++++APE A+ G +T+KSDV+SFG+++ EL+T GR P RE EQ G+ P Sbjct: 422 IKWTAPEAALFGRFTIKSDVWSFGILLTELITKGRIPYPGMNKREVLEQVEQGYHMP 478
>YES_XENLA (P10936) Tyrosine-protein kinase Yes (EC 2.7.10.2) (p61-Yes)| Length = 536 Score = 45.1 bits (105), Expect = 2e-04 Identities = 29/78 (37%), Positives = 45/78 (57%), Gaps = 10/78 (12%) Frame = -3 Query: 658 LEYSAPEFAMSGTYTVKSDVYSFGVVMLELLT-GRKPLDR--SRERSEQSLVGWATP--- 497 ++++APE A+ G +T+KSDV+SFG+++ EL+ GR P +RE EQ G+ P Sbjct: 429 IKWTAPEAALYGRFTIKSDVWSFGILLTELVAKGRVPYPGMVNREVLEQVERGYRMPCPQ 488 Query: 496 ----QLHDIDALAKMVDP 455 LH++ L DP Sbjct: 489 RCPESLHELMKLCWKKDP 506
>PKN2_BACSU (O34507) Probable serine/threonine-protein kinase yloP (EC| 2.7.11.1) Length = 648 Score = 45.1 bits (105), Expect = 2e-04 Identities = 20/38 (52%), Positives = 26/38 (68%) Frame = -3 Query: 658 LEYSAPEFAMSGTYTVKSDVYSFGVVMLELLTGRKPLD 545 + Y +PE A G T KSD+Y+ G+V+ ELLTGR P D Sbjct: 174 VHYLSPEQARGGLATKKSDIYALGIVLFELLTGRIPFD 211
>YES_CANFA (Q28923) Proto-oncogene tyrosine-protein kinase Yes (EC 2.7.10.2)| (p61-Yes) (c-Yes) Length = 538 Score = 45.1 bits (105), Expect = 2e-04 Identities = 30/78 (38%), Positives = 44/78 (56%), Gaps = 10/78 (12%) Frame = -3 Query: 658 LEYSAPEFAMSGTYTVKSDVYSFGVVMLELLT-GRKPLDR--SRERSEQSLVGWATP--- 497 ++++APE A+ G +T+KSDV+SFG++ EL T GR P +RE EQ G+ P Sbjct: 431 IKWTAPEAALYGRFTIKSDVWSFGILQTELTTKGRVPYPGMVNREVLEQVERGYRMPCPQ 490 Query: 496 ----QLHDIDALAKMVDP 455 LH++ L DP Sbjct: 491 GCPESLHELMNLCWKKDP 508
>SRC_AVIST (P14085) Tyrosine-protein kinase transforming protein Src (EC| 2.7.10.2) (p60-Src) (v-Src) (pp60v-src) Length = 556 Score = 44.7 bits (104), Expect = 3e-04 Identities = 29/78 (37%), Positives = 44/78 (56%), Gaps = 10/78 (12%) Frame = -3 Query: 658 LEYSAPEFAMSGTYTVKSDVYSFGVVMLELLT-GRKPLDR--SRERSEQSLVGWATP--- 497 ++++APE A+ G +T+KSDV+SFG+++ EL T GR P +RE +Q G+ P Sbjct: 425 IKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERGYRMPCPP 484 Query: 496 ----QLHDIDALAKMVDP 455 LHD+ DP Sbjct: 485 ECPESLHDLMCQCWRKDP 502
>SRC_AVISS (P14084) Tyrosine-protein kinase transforming protein Src (EC| 2.7.10.2) (p60-Src) (v-Src) (pp60v-src) Length = 567 Score = 44.7 bits (104), Expect = 3e-04 Identities = 29/78 (37%), Positives = 44/78 (56%), Gaps = 10/78 (12%) Frame = -3 Query: 658 LEYSAPEFAMSGTYTVKSDVYSFGVVMLELLT-GRKPLDR--SRERSEQSLVGWATP--- 497 ++++APE A+ G +T+KSDV+SFG+++ EL T GR P +RE +Q G+ P Sbjct: 425 IKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERGYRMPCPP 484 Query: 496 ----QLHDIDALAKMVDP 455 LHD+ DP Sbjct: 485 ECPESLHDLMCQCWRKDP 502
>SRC_RSVP (P00526) Tyrosine-protein kinase transforming protein Src (EC| 2.7.10.2) (p60-Src) (v-Src) (pp60v-src) Length = 525 Score = 44.7 bits (104), Expect = 3e-04 Identities = 29/78 (37%), Positives = 44/78 (56%), Gaps = 10/78 (12%) Frame = -3 Query: 658 LEYSAPEFAMSGTYTVKSDVYSFGVVMLELLT-GRKPLDR--SRERSEQSLVGWATP--- 497 ++++APE A+ G +T+KSDV+SFG+++ EL T GR P +RE +Q G+ P Sbjct: 425 IKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERGYRMPCPP 484 Query: 496 ----QLHDIDALAKMVDP 455 LHD+ DP Sbjct: 485 ECPESLHDLMCQCWRKDP 502
>SRC_CHICK (P00523) Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2)| (p60-Src) (c-Src) (pp60c-src) Length = 532 Score = 44.7 bits (104), Expect = 3e-04 Identities = 29/78 (37%), Positives = 44/78 (56%), Gaps = 10/78 (12%) Frame = -3 Query: 658 LEYSAPEFAMSGTYTVKSDVYSFGVVMLELLT-GRKPLDR--SRERSEQSLVGWATP--- 497 ++++APE A+ G +T+KSDV+SFG+++ EL T GR P +RE +Q G+ P Sbjct: 425 IKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERGYRMPCPP 484 Query: 496 ----QLHDIDALAKMVDP 455 LHD+ DP Sbjct: 485 ECPESLHDLMCQCWRKDP 502
>YES_XIPHE (P27447) Tyrosine-protein kinase Yes (EC 2.7.10.2) (p61-Yes)| Length = 543 Score = 44.7 bits (104), Expect = 3e-04 Identities = 25/57 (43%), Positives = 39/57 (68%), Gaps = 3/57 (5%) Frame = -3 Query: 658 LEYSAPEFAMSGTYTVKSDVYSFGVVMLELLT-GRKPLDR--SRERSEQSLVGWATP 497 ++++APE A+ G +T+KSDV+SFG+++ EL+T GR P +RE EQ G+ P Sbjct: 436 IKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMVNREVLEQVDRGYRMP 492
>FGR_FSVGR (P00544) Tyrosine-protein kinase transforming protein Fgr (EC| 2.7.10.2) Length = 545 Score = 44.3 bits (103), Expect = 3e-04 Identities = 24/57 (42%), Positives = 39/57 (68%), Gaps = 3/57 (5%) Frame = -3 Query: 658 LEYSAPEFAMSGTYTVKSDVYSFGVVMLELLT-GRKPLD--RSRERSEQSLVGWATP 497 ++++APE A+ G +T+KSDV+SFG+++ EL++ GR P +RE EQ G+ P Sbjct: 445 IKWTAPEAALFGRFTIKSDVWSFGILLTELISKGRVPYPGMNNREVLEQVEHGYHMP 501
>IRAK3_MOUSE (Q8K4B2) Interleukin-1 receptor-associated kinase 3 (EC 2.7.11.1)| (IRAK-3) (IL-1 receptor-associated kinase M) (IRAK-M) Length = 609 Score = 44.3 bits (103), Expect = 3e-04 Identities = 31/109 (28%), Positives = 53/109 (48%), Gaps = 1/109 (0%) Frame = -3 Query: 661 HLEYSAPEFAMSGTYTVKSDVYSFGVVMLELLTGRK-PLDRSRERSEQSLVGWATPQLHD 485 HL Y E+ G +VK+DVYSFG+V++E+LTG K LD + + L+ + Sbjct: 350 HLWYMPEEYIRQGRLSVKTDVYSFGIVIMEVLTGCKVVLDDPKHVQLRDLL-MELMEKRG 408 Query: 484 IDALAKMVDPAMDGMYPAKSLSRFADIIALSVQPEPEFRPPISEVVQQL 338 +D+ +D + P ++ + V + + RP + EV+ L Sbjct: 409 LDSCLSFLDRKIPPC-PRNFSAKLFSLAGRCVATKAKLRPTMDEVLSSL 456
>SRK1_SPOLA (P42686) Tyrosine-protein kinase isoform SRK1 (EC 2.7.10.2)| Length = 505 Score = 44.3 bits (103), Expect = 3e-04 Identities = 28/79 (35%), Positives = 42/79 (53%), Gaps = 10/79 (12%) Frame = -3 Query: 658 LEYSAPEFAMSGTYTVKSDVYSFGVVMLELLT-GRKP---------LDRSRERSEQSLVG 509 ++++APE AM +T+KSDV+SFGVV+ E++T GR P L++ ++ Sbjct: 399 IKWTAPEAAMYNRFTIKSDVWSFGVVLYEIITYGRFPYPGMTNPEVLEKIQQNYRMPCPA 458 Query: 508 WATPQLHDIDALAKMVDPA 452 Q HDI DPA Sbjct: 459 NCPKQFHDIMLDCWREDPA 477
>SRC_RAT (Q9WUD9) Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2)| (p60-Src) (c-Src) (pp60c-src) Length = 535 Score = 43.9 bits (102), Expect = 4e-04 Identities = 27/69 (39%), Positives = 42/69 (60%), Gaps = 10/69 (14%) Frame = -3 Query: 658 LEYSAPEFAMSGTYTVKSDVYSFGVVMLELLT-GRKPLDR--SRERSEQSLVGWATP--- 497 ++++APE A+ G +T+KSDV+SFG+++ EL T GR P +RE +Q G+ P Sbjct: 428 IKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERGYRMPCPP 487 Query: 496 ----QLHDI 482 LHD+ Sbjct: 488 ECPESLHDL 496
>SRC_HUMAN (P12931) Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2)| (p60-Src) (c-Src) (pp60c-src) Length = 535 Score = 43.9 bits (102), Expect = 4e-04 Identities = 27/69 (39%), Positives = 42/69 (60%), Gaps = 10/69 (14%) Frame = -3 Query: 658 LEYSAPEFAMSGTYTVKSDVYSFGVVMLELLT-GRKPLDR--SRERSEQSLVGWATP--- 497 ++++APE A+ G +T+KSDV+SFG+++ EL T GR P +RE +Q G+ P Sbjct: 428 IKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERGYRMPCPP 487 Query: 496 ----QLHDI 482 LHD+ Sbjct: 488 ECPESLHDL 496
>PGFRB_RAT (Q05030) Beta platelet-derived growth factor receptor precursor (EC| 2.7.10.1) (PDGF-R-beta) Length = 1097 Score = 43.9 bits (102), Expect = 4e-04 Identities = 33/124 (26%), Positives = 53/124 (42%) Frame = -3 Query: 658 LEYSAPEFAMSGTYTVKSDVYSFGVVMLELLTGRKPLDRSRERSEQSLVGWATPQLHDID 479 L++ APE + YT SDV+SFG+++ E+ T L G P+L D Sbjct: 866 LKWMAPESIFNSLYTTLSDVWSFGILLWEIFT---------------LGGTPYPELPMND 910 Query: 478 ALAKMVDPAMDGMYPAKSLSRFADIIALSVQPEPEFRPPISEVVQQLVRLMQRASMLRRQ 299 + PA + +I+ + + E RPP S++V L RL+ + Q Sbjct: 911 QFYNAIKRGYRMAQPAHASDEIYEIMQKCWEEKFETRPPFSQLVLLLERLLGEGYKKKYQ 970 Query: 298 SGDD 287 D+ Sbjct: 971 QVDE 974
>SRC2_XENLA (P13116) Tyrosine-protein kinase Src-2 (EC 2.7.10.2) (p60-Src-2)| Length = 531 Score = 43.9 bits (102), Expect = 4e-04 Identities = 27/69 (39%), Positives = 42/69 (60%), Gaps = 10/69 (14%) Frame = -3 Query: 658 LEYSAPEFAMSGTYTVKSDVYSFGVVMLELLT-GRKPLDR--SRERSEQSLVGWATP--- 497 ++++APE A+ G +T+KSDV+SFG+++ EL T GR P +RE +Q G+ P Sbjct: 424 IKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERGYRMPCPP 483 Query: 496 ----QLHDI 482 LHD+ Sbjct: 484 DCPESLHDL 492
>SRC1_XENLA (P13115) Tyrosine-protein kinase Src-1 (EC 2.7.10.2) (p60-Src-1)| Length = 531 Score = 43.9 bits (102), Expect = 4e-04 Identities = 27/69 (39%), Positives = 42/69 (60%), Gaps = 10/69 (14%) Frame = -3 Query: 658 LEYSAPEFAMSGTYTVKSDVYSFGVVMLELLT-GRKPLDR--SRERSEQSLVGWATP--- 497 ++++APE A+ G +T+KSDV+SFG+++ EL T GR P +RE +Q G+ P Sbjct: 424 IKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERGYRMPCPP 483 Query: 496 ----QLHDI 482 LHD+ Sbjct: 484 DCPESLHDL 492
>SRC_MOUSE (P05480) Neuronal proto-oncogene tyrosine-protein kinase Src (EC| 2.7.10.2) (p60-Src) (c-Src) (pp60c-src) Length = 540 Score = 43.9 bits (102), Expect = 4e-04 Identities = 27/69 (39%), Positives = 42/69 (60%), Gaps = 10/69 (14%) Frame = -3 Query: 658 LEYSAPEFAMSGTYTVKSDVYSFGVVMLELLT-GRKPLDR--SRERSEQSLVGWATP--- 497 ++++APE A+ G +T+KSDV+SFG+++ EL T GR P +RE +Q G+ P Sbjct: 433 IKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERGYRMPCPP 492 Query: 496 ----QLHDI 482 LHD+ Sbjct: 493 ECPESLHDL 501
>YR831_MIMIV (Q7T6Y2) Putative serine/threonine-protein kinase/receptor R831| precursor (EC 2.7.11.1) Length = 1624 Score = 43.9 bits (102), Expect = 4e-04 Identities = 32/114 (28%), Positives = 52/114 (45%), Gaps = 3/114 (2%) Frame = -3 Query: 652 YSAPEFAMSGTYTVKSDVYSFGVVMLELLTGRKPLDRSRERSEQSLVGWATPQLHDIDAL 473 ++APE Y K+DV+SFGVVM E+LTG++P Sbjct: 1526 WTAPEVIRGEKYCEKADVFSFGVVMWEVLTGKEPFAECN--------------------F 1565 Query: 472 AKMVDPAMDG---MYPAKSLSRFADIIALSVQPEPEFRPPISEVVQQLVRLMQR 320 K+ ++G + P+ FA +I + RP ++EVVQQL+ + ++ Sbjct: 1566 MKVSLDILEGGRPIIPSDCPHEFAKLIKKCWHAKAHKRPTMTEVVQQLMLITEQ 1619 Score = 32.0 bits (71), Expect = 1.7 Identities = 29/118 (24%), Positives = 49/118 (41%), Gaps = 3/118 (2%) Frame = -3 Query: 658 LEYSAPEFAMSGTYT--VKSDVYSFGVVMLELLTGRKPLDRSRERSEQSLVGWATPQLHD 485 + + APE T + +DVYSFG+++ ELLT +P TP Sbjct: 949 IHWIAPEILNDSTEVDYILADVYSFGIILWELLTREQPYK------------GMTPAAIA 996 Query: 484 IDALAK-MVDPAMDGMYPAKSLSRFADIIALSVQPEPEFRPPISEVVQQLVRLMQRAS 314 + + M P D A S+ + D+I + RP E++ +L ++ +S Sbjct: 997 VSVIRDGMRPPISDEAVTAHSI-EYIDLIKQCWHSDTIIRPTFLEIMTRLSNILGDSS 1053
>M3K10_HUMAN (Q02779) Mitogen-activated protein kinase kinase kinase 10 (EC| 2.7.11.25) (Mixed lineage kinase 2) (Protein kinase MST) Length = 954 Score = 43.9 bits (102), Expect = 4e-04 Identities = 33/115 (28%), Positives = 51/115 (44%), Gaps = 3/115 (2%) Frame = -3 Query: 652 YSAPEFAMSGTYTVKSDVYSFGVVMLELLTGRKPLDRSRERSEQSLVGWATPQLHDIDAL 473 + APE ++ SDV+SFGV++ ELLTG P +IDAL Sbjct: 269 WMAPEVIRLSLFSKSSDVWSFGVLLWELLTGEVP-------------------YREIDAL 309 Query: 472 AKMVDPAMDGM---YPAKSLSRFADIIALSVQPEPEFRPPISEVVQQLVRLMQRA 317 A AM+ + P+ FA ++ P+P RP ++++L + Q A Sbjct: 310 AVAYGVAMNKLTLPIPSTCPEPFARLLEECWDPDPHGRPDFGSILKRLEVIEQSA 364
>PGFRB_MOUSE (P05622) Beta platelet-derived growth factor receptor precursor (EC| 2.7.10.1) (PDGF-R-beta) Length = 1098 Score = 43.9 bits (102), Expect = 4e-04 Identities = 33/124 (26%), Positives = 53/124 (42%) Frame = -3 Query: 658 LEYSAPEFAMSGTYTVKSDVYSFGVVMLELLTGRKPLDRSRERSEQSLVGWATPQLHDID 479 L++ APE + YT SDV+SFG+++ E+ T L G P+L D Sbjct: 866 LKWMAPESIFNSLYTTLSDVWSFGILLWEIFT---------------LGGTPYPELPMND 910 Query: 478 ALAKMVDPAMDGMYPAKSLSRFADIIALSVQPEPEFRPPISEVVQQLVRLMQRASMLRRQ 299 + PA + +I+ + + E RPP S++V L RL+ + Q Sbjct: 911 QFYNAIKRGYRMAQPAHASDEIYEIMQKCWEEKFETRPPFSQLVLLLERLLGEGYKKKYQ 970 Query: 298 SGDD 287 D+ Sbjct: 971 QVDE 974
>PKNL_MYCTU (O53510) Probable serine/threonine-protein kinase pknL (EC| 2.7.11.1) Length = 399 Score = 43.5 bits (101), Expect = 6e-04 Identities = 37/118 (31%), Positives = 50/118 (42%), Gaps = 21/118 (17%) Frame = -3 Query: 652 YSAPEFAMSGTYTVKSDVYSFGVVMLELLTGRKP-------------LDRSRERSEQSLV 512 Y +PE G +SDVYS GV++ ELLTG P LD R+ +++ Sbjct: 184 YLSPEQVRDGNADPRSDVYSVGVLVYELLTGHTPFTGDSALSIAYQRLDADVPRA-SAVI 242 Query: 511 GWATPQLHDIDALAKMVDPAMDGMYPAKSLSRFADIIALSVQPE--------PEFRPP 362 PQ ++ A A +PA R+AD IA+ E PEFR P Sbjct: 243 DGVPPQFDELVACATARNPA----------DRYADAIAMGADLEAIAEELALPEFRVP 290
>PKNL_MYCBO (Q7TYY6) Probable serine/threonine-protein kinase pknL (EC| 2.7.11.1) Length = 399 Score = 43.5 bits (101), Expect = 6e-04 Identities = 37/118 (31%), Positives = 50/118 (42%), Gaps = 21/118 (17%) Frame = -3 Query: 652 YSAPEFAMSGTYTVKSDVYSFGVVMLELLTGRKP-------------LDRSRERSEQSLV 512 Y +PE G +SDVYS GV++ ELLTG P LD R+ +++ Sbjct: 184 YLSPEQVRDGNADPRSDVYSVGVLVYELLTGHTPFTGDSALSIAYQRLDADVPRA-SAVI 242 Query: 511 GWATPQLHDIDALAKMVDPAMDGMYPAKSLSRFADIIALSVQPE--------PEFRPP 362 PQ ++ A A +PA R+AD IA+ E PEFR P Sbjct: 243 DGVPPQFDELVACATARNPA----------DRYADAIAMGADLEAIAEELALPEFRVP 290
>PGFRB_CANFA (Q6QNF3) Beta platelet-derived growth factor receptor precursor (EC| 2.7.10.1) (PDGF-R-beta) Length = 1103 Score = 43.1 bits (100), Expect = 7e-04 Identities = 32/124 (25%), Positives = 53/124 (42%) Frame = -3 Query: 658 LEYSAPEFAMSGTYTVKSDVYSFGVVMLELLTGRKPLDRSRERSEQSLVGWATPQLHDID 479 L++ APE + YT SDV+SFG+++ E+ T L G P+L + Sbjct: 867 LKWMAPESIFNSLYTTLSDVWSFGILLWEIFT---------------LGGTPYPELPMNE 911 Query: 478 ALAKMVDPAMDGMYPAKSLSRFADIIALSVQPEPEFRPPISEVVQQLVRLMQRASMLRRQ 299 + PA + +I+ + + E RPP S++V L RL+ + Q Sbjct: 912 QFYNAIKRGYRMAQPAHASDEIYEIMQKCWEEKFEIRPPFSQLVLLLERLLGEGYKKKYQ 971 Query: 298 SGDD 287 D+ Sbjct: 972 QVDE 975
>SIRK_ARATH (O64483) Senescence-induced receptor-like serine/threonine-protein| kinase precursor (FLG22-induced receptor-like kinase 1) Length = 876 Score = 43.1 bits (100), Expect = 7e-04 Identities = 29/109 (26%), Positives = 54/109 (49%) Frame = -3 Query: 652 YSAPEFAMSGTYTVKSDVYSFGVVMLELLTGRKPLDRSRERSEQSLVGWATPQLHDIDAL 473 Y PE+ + KSDVYS GVV+LE++TG+ + S ++E+ + + + Sbjct: 740 YLDPEYYSTRQMNEKSDVYSLGVVLLEVITGQPAIASS--KTEKVHISDHVRSILANGDI 797 Query: 472 AKMVDPAMDGMYPAKSLSRFADIIALSVQPEPEFRPPISEVVQQLVRLM 326 +VD + Y S + ++I + RP +S+VV +L +++ Sbjct: 798 RGIVDQRLRERYDVGSAWKMSEIALACTEHTSAQRPTMSQVVMELKQIV 846
>KPRO_MAIZE (P17801) Putative receptor protein kinase ZmPK1 precursor (EC| 2.7.11.1) Length = 817 Score = 43.1 bits (100), Expect = 7e-04 Identities = 29/73 (39%), Positives = 40/73 (54%), Gaps = 1/73 (1%) Frame = -3 Query: 658 LEYSAPEFAMSGTYTVKSDVYSFGVVMLELLTGRKPLDRSRERSEQSLVGWATPQLHD-I 482 L Y APE+ S T K DVYS+GVV+LELLTG + LVG T ++H + Sbjct: 699 LGYIAPEWVSSLPITAKVDVYSYGVVLLELLTGTR---------VSELVG-GTDEVHSML 748 Query: 481 DALAKMVDPAMDG 443 L +M+ ++G Sbjct: 749 RKLVRMLSAKLEG 761
>PGFRB_HUMAN (P09619) Beta platelet-derived growth factor receptor precursor (EC| 2.7.10.1) (PDGF-R-beta) (CD140b antigen) Length = 1106 Score = 43.1 bits (100), Expect = 7e-04 Identities = 32/124 (25%), Positives = 53/124 (42%) Frame = -3 Query: 658 LEYSAPEFAMSGTYTVKSDVYSFGVVMLELLTGRKPLDRSRERSEQSLVGWATPQLHDID 479 L++ APE + YT SDV+SFG+++ E+ T L G P+L + Sbjct: 867 LKWMAPESIFNSLYTTLSDVWSFGILLWEIFT---------------LGGTPYPELPMNE 911 Query: 478 ALAKMVDPAMDGMYPAKSLSRFADIIALSVQPEPEFRPPISEVVQQLVRLMQRASMLRRQ 299 + PA + +I+ + + E RPP S++V L RL+ + Q Sbjct: 912 QFYNAIKRGYRMAQPAHASDEIYEIMQKCWEEKFEIRPPFSQLVLLLERLLGEGYKKKYQ 971 Query: 298 SGDD 287 D+ Sbjct: 972 QVDE 975
>SRC_RSVSE (P63185) Tyrosine-protein kinase transforming protein Src (EC| 2.7.10.2) (p60-Src) (v-Src) (pp60v-src) Length = 525 Score = 42.7 bits (99), Expect = 0.001 Identities = 19/37 (51%), Positives = 30/37 (81%), Gaps = 1/37 (2%) Frame = -3 Query: 658 LEYSAPEFAMSGTYTVKSDVYSFGVVMLELLT-GRKP 551 ++++APE A+ G +T+KSDV+SFG+++ EL T GR P Sbjct: 425 IKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVP 461
>SRC_RSVSA (P00524) Tyrosine-protein kinase transforming protein Src (EC| 2.7.10.2) (p60-Src) (v-Src) (pp60v-src) Length = 525 Score = 42.7 bits (99), Expect = 0.001 Identities = 19/37 (51%), Positives = 30/37 (81%), Gaps = 1/37 (2%) Frame = -3 Query: 658 LEYSAPEFAMSGTYTVKSDVYSFGVVMLELLT-GRKP 551 ++++APE A+ G +T+KSDV+SFG+++ EL T GR P Sbjct: 425 IKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVP 461
>SRC_RSVH1 (P25020) Tyrosine-protein kinase transforming protein Src (EC| 2.7.10.2) (p60-Src) (v-Src) (pp60v-src) Length = 525 Score = 42.7 bits (99), Expect = 0.001 Identities = 19/37 (51%), Positives = 30/37 (81%), Gaps = 1/37 (2%) Frame = -3 Query: 658 LEYSAPEFAMSGTYTVKSDVYSFGVVMLELLT-GRKP 551 ++++APE A+ G +T+KSDV+SFG+++ EL T GR P Sbjct: 425 IKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVP 461
>SRC_AVISR (P00525) Tyrosine-protein kinase transforming protein Src (EC| 2.7.10.2) (p60-Src) (v-Src) (pp60v-src) Length = 525 Score = 42.7 bits (99), Expect = 0.001 Identities = 19/37 (51%), Positives = 30/37 (81%), Gaps = 1/37 (2%) Frame = -3 Query: 658 LEYSAPEFAMSGTYTVKSDVYSFGVVMLELLT-GRKP 551 ++++APE A+ G +T+KSDV+SFG+++ EL T GR P Sbjct: 425 IKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVP 461
>SRK4_SPOLA (P42690) Tyrosine-protein kinase isoform SRK4 (EC 2.7.10.2)| Length = 506 Score = 42.4 bits (98), Expect = 0.001 Identities = 19/37 (51%), Positives = 30/37 (81%), Gaps = 1/37 (2%) Frame = -3 Query: 658 LEYSAPEFAMSGTYTVKSDVYSFGVVMLELLT-GRKP 551 ++++APE AM +T+KSDV+SFG+V+ E++T GR P Sbjct: 399 IKWTAPEAAMYSRFTIKSDVWSFGIVLYEVITYGRFP 435
>SRC_RSVPA (P31693) Tyrosine-protein kinase transforming protein Src (EC| 2.7.10.2) (p60-Src) (v-Src) (pp60v-src) Length = 522 Score = 42.4 bits (98), Expect = 0.001 Identities = 19/37 (51%), Positives = 30/37 (81%), Gaps = 1/37 (2%) Frame = -3 Query: 658 LEYSAPEFAMSGTYTVKSDVYSFGVVMLELLT-GRKP 551 ++++APE A+ G +T+KSDV+SFG+++ EL T GR P Sbjct: 422 VKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVP 458
>LCK_SAISC (Q95KR7) Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2)| (p56-LCK) (Lymphocyte cell-specific protein-tyrosine kinase) Length = 508 Score = 42.4 bits (98), Expect = 0.001 Identities = 19/37 (51%), Positives = 30/37 (81%), Gaps = 1/37 (2%) Frame = -3 Query: 658 LEYSAPEFAMSGTYTVKSDVYSFGVVMLELLT-GRKP 551 ++++APE GT+T+KSDV+SFG++M E++T GR P Sbjct: 403 IKWTAPEAINYGTFTIKSDVWSFGILMTEIVTHGRIP 439
>PKNB_LACLA (Q9CEF5) Probable serine/threonine-protein kinase pknB (EC| 2.7.11.1) Length = 627 Score = 42.0 bits (97), Expect = 0.002 Identities = 17/38 (44%), Positives = 26/38 (68%) Frame = -3 Query: 658 LEYSAPEFAMSGTYTVKSDVYSFGVVMLELLTGRKPLD 545 + Y +PE A TV+SD+Y+ G+++ ELLTG+ P D Sbjct: 176 VHYLSPEQARGSNATVQSDIYAIGIILFELLTGQIPFD 213
>PKNB_BIFLO (Q8G6P9) Probable serine/threonine-protein kinase pknB (EC| 2.7.11.1) Length = 690 Score = 42.0 bits (97), Expect = 0.002 Identities = 26/68 (38%), Positives = 37/68 (54%), Gaps = 2/68 (2%) Frame = -3 Query: 655 EYSAPEFAMSGTYTVKSDVYSFGVVMLELLTGRKPL--DRSRERSEQSLVGWATPQLHDI 482 +Y +PE A T ++SD+YS G V+ E+LTGR P D + + Q + ATP + Sbjct: 189 QYLSPEQARGETVDMRSDLYSAGCVLYEMLTGRPPFTGDSAVAIAYQHVSEVATPPSAAV 248 Query: 481 DALAKMVD 458 L KM D Sbjct: 249 PGLPKMWD 256
>IRAK3_HUMAN (Q9Y616) Interleukin-1 receptor-associated kinase 3 (EC 2.7.11.1)| (IRAK-3) (IL-1 receptor-associated kinase M) (IRAK-M) Length = 596 Score = 42.0 bits (97), Expect = 0.002 Identities = 17/34 (50%), Positives = 25/34 (73%) Frame = -3 Query: 661 HLEYSAPEFAMSGTYTVKSDVYSFGVVMLELLTG 560 HL Y E+ G ++K+DVYSFG+V++E+LTG Sbjct: 337 HLWYMPEEYIRQGKLSIKTDVYSFGIVIMEVLTG 370
>MATK_HUMAN (P42679) Megakaryocyte-associated tyrosine-protein kinase (EC| 2.7.10.2) (Tyrosine-protein kinase CTK) (Protein kinase HYL) (Hematopoietic consensus tyrosine-lacking kinase) Length = 507 Score = 41.6 bits (96), Expect = 0.002 Identities = 36/132 (27%), Positives = 59/132 (44%), Gaps = 4/132 (3%) Frame = -3 Query: 658 LEYSAPEFAMSGTYTVKSDVYSFGVVMLELLT-GRKPLDRS--RERSEQSLVGWATPQLH 488 ++++APE G +T KSDV+SFGV++ E+ + GR P + +E SE G+ Sbjct: 388 VKWTAPEALKHGKFTSKSDVWSFGVLLWEVFSYGRAPYPKMSLKEVSEAVEKGYR----- 442 Query: 487 DIDALAKMVDPAMDGMYPAKSLSRFADIIALSV-QPEPEFRPPISEVVQQLVRLMQRASM 311 M P + ++ S + EP RPP ++ ++L R ++ A Sbjct: 443 ---------------MEPPEGCPGPVHVLMSSCWEAEPARRPPFRKLAEKLARELRSAGA 487 Query: 310 LRRQSGDDLGSS 275 SG D S Sbjct: 488 PASVSGQDADGS 499
>MATK_RAT (P41243) Megakaryocyte-associated tyrosine-protein kinase (EC| 2.7.10.2) (Tyrosine-protein kinase CTK) (Protein kinase BATK) Length = 467 Score = 41.6 bits (96), Expect = 0.002 Identities = 37/137 (27%), Positives = 64/137 (46%), Gaps = 3/137 (2%) Frame = -3 Query: 658 LEYSAPEFAMSGTYTVKSDVYSFGVVMLELLT-GRKPLDRS--RERSEQSLVGWATPQLH 488 ++++APE +G ++ KSDV+SFGV++ E+ + GR P + +E SE G+ ++ Sbjct: 348 VKWTAPEALKNGRFSSKSDVWSFGVLLWEVFSYGRAPYPKMSLKEVSEAVEKGY---RME 404 Query: 487 DIDALAKMVDPAMDGMYPAKSLSRFADIIALSVQPEPEFRPPISEVVQQLVRLMQRASML 308 D+ V M + A EP RPP ++V++L R ++ + Sbjct: 405 PPDSCPGPVHTLMGSCWEA----------------EPSRRPPFRKIVEKLGRELRSVGVA 448 Query: 307 RRQSGDDLGSSYRAPER 257 G + S AP R Sbjct: 449 APAGGQEAEGS--APTR 463
>M3K9_HUMAN (P80192) Mitogen-activated protein kinase kinase kinase 9 (EC| 2.7.11.25) (Mixed lineage kinase 1) Length = 1104 Score = 41.6 bits (96), Expect = 0.002 Identities = 30/111 (27%), Positives = 48/111 (43%), Gaps = 3/111 (2%) Frame = -3 Query: 652 YSAPEFAMSGTYTVKSDVYSFGVVMLELLTGRKPLDRSRERSEQSLVGWATPQLHDIDAL 473 + APE + ++ SDV+S+GV++ ELLTG P ID L Sbjct: 315 WMAPEVIRASMFSKGSDVWSYGVLLWELLTGEVP-------------------FRGIDGL 355 Query: 472 AKMVDPAMDGM---YPAKSLSRFADIIALSVQPEPEFRPPISEVVQQLVRL 329 A AM+ + P+ FA ++ P+P RP + ++ QL + Sbjct: 356 AVAYGVAMNKLALPIPSTCPEPFAKLMEDCWNPDPHSRPSFTNILDQLTTI 406
>STK24_HUMAN (Q9Y6E0) Serine/threonine-protein kinase 24 (EC 2.7.11.1)| (STE20-like kinase MST3) (MST-3) (Mammalian STE20-like protein kinase 3) Length = 443 Score = 41.6 bits (96), Expect = 0.002 Identities = 40/153 (26%), Positives = 61/153 (39%), Gaps = 16/153 (10%) Frame = -3 Query: 652 YSAPEFAMSGTYTVKSDVYSFGVVMLELLTGRKPLDRSRERSEQSLVGWATPQLHDIDAL 473 + APE Y K+D++S G+ +EL G P +LH + L Sbjct: 197 WMAPEVIKQSAYDSKADIWSLGITAIELARGEPP----------------HSELHPMKVL 240 Query: 472 ---AKMVDPAMDGMYPAKSLSRFADIIALSVQPEPEFRPPISEVVQQ--LVRLMQRASML 308 K P ++G Y +K L F + + EP FRP E+++ ++R ++ S L Sbjct: 241 FLIPKNNPPTLEGNY-SKPLKEF---VEACLNKEPSFRPTAKELLKHKFILRNAKKTSYL 296 Query: 307 -----------RRQSGDDLGSSYRAPEREGGAS 242 QS DD S E +G AS Sbjct: 297 TELIDRYKRWKAEQSHDDSSSEDSDAETDGQAS 329
>MEK2_CAEEL (Q10664) Dual specificity mitogen-activated protein kinase kinase| mek-2 (EC 2.7.12.2) (MAP kinase kinase mek-2) Length = 387 Score = 41.6 bits (96), Expect = 0.002 Identities = 20/60 (33%), Positives = 33/60 (55%) Frame = -3 Query: 652 YSAPEFAMSGTYTVKSDVYSFGVVMLELLTGRKPLDRSRERSEQSLVGWATPQLHDIDAL 473 Y APE YT+ SD++SFG+ ++ELL GR P+ + ++ A ++ D+L Sbjct: 234 YMAPERLTGSHYTISSDIWSFGLSLVELLIGRYPVPAPSQAEYATMFNVAENEIELADSL 293
>LCK_MOUSE (P06240) Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2)| (p56-LCK) (Lymphocyte cell-specific protein-tyrosine kinase) (LSK) Length = 508 Score = 41.2 bits (95), Expect = 0.003 Identities = 18/37 (48%), Positives = 30/37 (81%), Gaps = 1/37 (2%) Frame = -3 Query: 658 LEYSAPEFAMSGTYTVKSDVYSFGVVMLELLT-GRKP 551 ++++APE GT+T+KSDV+SFG+++ E++T GR P Sbjct: 403 IKWTAPEAINYGTFTIKSDVWSFGILLTEIVTHGRIP 439
>LCK_HUMAN (P06239) Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2)| (p56-LCK) (Lymphocyte cell-specific protein-tyrosine kinase) (LSK) (T cell-specific protein-tyrosine kinase) Length = 508 Score = 41.2 bits (95), Expect = 0.003 Identities = 18/37 (48%), Positives = 30/37 (81%), Gaps = 1/37 (2%) Frame = -3 Query: 658 LEYSAPEFAMSGTYTVKSDVYSFGVVMLELLT-GRKP 551 ++++APE GT+T+KSDV+SFG+++ E++T GR P Sbjct: 403 IKWTAPEAINYGTFTIKSDVWSFGILLTEIVTHGRIP 439
>LCK_AOTNA (Q5PXS1) Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2)| (p56-LCK) (Lymphocyte cell-specific protein-tyrosine kinase) Length = 508 Score = 41.2 bits (95), Expect = 0.003 Identities = 18/37 (48%), Positives = 30/37 (81%), Gaps = 1/37 (2%) Frame = -3 Query: 658 LEYSAPEFAMSGTYTVKSDVYSFGVVMLELLT-GRKP 551 ++++APE GT+T+KSDV+SFG+++ E++T GR P Sbjct: 403 IKWTAPEAINYGTFTIKSDVWSFGILLTEIVTHGRIP 439
>STK_HYDAT (P17713) Tyrosine-protein kinase STK (EC 2.7.10.2) (P57-STK)| Length = 509 Score = 41.2 bits (95), Expect = 0.003 Identities = 18/37 (48%), Positives = 30/37 (81%), Gaps = 1/37 (2%) Frame = -3 Query: 658 LEYSAPEFAMSGTYTVKSDVYSFGVVMLELLT-GRKP 551 ++++APE A+ +T+KSDV+SFG++M E++T GR P Sbjct: 400 IKWTAPEAALYNRFTIKSDVWSFGILMAEIVTKGRIP 436
>LCK_CHICK (P42683) Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2)| (Protein-tyrosine kinase C-TKL) (p56tk1) Length = 507 Score = 41.2 bits (95), Expect = 0.003 Identities = 18/37 (48%), Positives = 30/37 (81%), Gaps = 1/37 (2%) Frame = -3 Query: 658 LEYSAPEFAMSGTYTVKSDVYSFGVVMLELLT-GRKP 551 ++++APE GT+T+KSDV+SFG+++ E++T GR P Sbjct: 402 IKWTAPEAINYGTFTIKSDVWSFGILLTEIVTYGRIP 438
>HCK_RAT (P50545) Tyrosine-protein kinase HCK (EC 2.7.10.2) (p56-HCK)| (Hemopoietic cell kinase) Length = 502 Score = 40.8 bits (94), Expect = 0.004 Identities = 17/37 (45%), Positives = 31/37 (83%), Gaps = 1/37 (2%) Frame = -3 Query: 658 LEYSAPEFAMSGTYTVKSDVYSFGVVMLELLT-GRKP 551 ++++APE G++T+KSDV+SFG++++E++T GR P Sbjct: 397 IKWTAPEAINFGSFTIKSDVWSFGILLMEIVTYGRIP 433
>HCK_MOUSE (P08103) Tyrosine-protein kinase HCK (EC 2.7.10.2)| (p56-HCK/p59-HCK) (Hemopoietic cell kinase) (B-cell/myeloid kinase) (BMK) Length = 523 Score = 40.8 bits (94), Expect = 0.004 Identities = 17/37 (45%), Positives = 31/37 (83%), Gaps = 1/37 (2%) Frame = -3 Query: 658 LEYSAPEFAMSGTYTVKSDVYSFGVVMLELLT-GRKP 551 ++++APE G++T+KSDV+SFG++++E++T GR P Sbjct: 418 IKWTAPEAINFGSFTIKSDVWSFGILLMEIVTYGRIP 454
>HCK_HUMAN (P08631) Tyrosine-protein kinase HCK (EC 2.7.10.2)| (p59-HCK/p60-HCK) (Hemopoietic cell kinase) Length = 525 Score = 40.8 bits (94), Expect = 0.004 Identities = 17/37 (45%), Positives = 31/37 (83%), Gaps = 1/37 (2%) Frame = -3 Query: 658 LEYSAPEFAMSGTYTVKSDVYSFGVVMLELLT-GRKP 551 ++++APE G++T+KSDV+SFG++++E++T GR P Sbjct: 420 IKWTAPEAINFGSFTIKSDVWSFGILLMEIVTYGRIP 456
>MATK_MOUSE (P41242) Megakaryocyte-associated tyrosine-protein kinase (EC| 2.7.10.2) (Tyrosine-protein kinase CTK) (Protein kinase NTK) Length = 505 Score = 40.8 bits (94), Expect = 0.004 Identities = 37/137 (27%), Positives = 63/137 (45%), Gaps = 3/137 (2%) Frame = -3 Query: 658 LEYSAPEFAMSGTYTVKSDVYSFGVVMLELLT-GRKPLDRS--RERSEQSLVGWATPQLH 488 ++++APE +G ++ KSDV+SFGV++ E+ + GR P + +E SE G+ ++ Sbjct: 386 VKWTAPEALKNGRFSSKSDVWSFGVLLWEVFSYGRAPYPKMSLKEVSEAVEKGY---RME 442 Query: 487 DIDALAKMVDPAMDGMYPAKSLSRFADIIALSVQPEPEFRPPISEVVQQLVRLMQRASML 308 D V M + A EP RPP ++V++L R ++ + Sbjct: 443 PPDGCPGSVHTLMGSCWEA----------------EPARRPPFRKIVEKLGRELRSVGVS 486 Query: 307 RRQSGDDLGSSYRAPER 257 G + S AP R Sbjct: 487 APAGGQEAEGS--APTR 501
>STK24_MOUSE (Q99KH8) Serine/threonine-protein kinase 24 (EC 2.7.11.1)| Length = 431 Score = 40.4 bits (93), Expect = 0.005 Identities = 39/153 (25%), Positives = 61/153 (39%), Gaps = 16/153 (10%) Frame = -3 Query: 652 YSAPEFAMSGTYTVKSDVYSFGVVMLELLTGRKPLDRSRERSEQSLVGWATPQLHDIDAL 473 + APE Y K+D++S G+ +EL G P +LH + L Sbjct: 185 WMAPEVIKQSAYDSKADIWSLGITAIELAKGEPP----------------HSELHPMKVL 228 Query: 472 ---AKMVDPAMDGMYPAKSLSRFADIIALSVQPEPEFRPPISEVVQQ--LVRLMQRASML 308 K P ++G Y +K L F + + EP FRP E+++ ++R ++ S L Sbjct: 229 FLIPKNNPPTLEGNY-SKPLKEF---VEACLNKEPSFRPTAKELLKHKFIIRNAKKTSYL 284 Query: 307 -----------RRQSGDDLGSSYRAPEREGGAS 242 QS +D S E +G AS Sbjct: 285 TELIDRYKRWKAEQSHEDSSSEDSDVETDGQAS 317
>INSR_HUMAN (P06213) Insulin receptor precursor (EC 2.7.10.1) (IR) (CD220| antigen) [Contains: Insulin receptor alpha subunit; Insulin receptor beta subunit] Length = 1382 Score = 40.4 bits (93), Expect = 0.005 Identities = 33/110 (30%), Positives = 49/110 (44%), Gaps = 3/110 (2%) Frame = -3 Query: 658 LEYSAPEFAMSGTYTVKSDVYSFGVVMLELLTGRKPLDRSRERSEQSLVGWATPQLHDID 479 + + APE G +T SD++SFGVV+ E+ + +EQ G + Q Sbjct: 1200 VRWMAPESLKDGVFTTSSDMWSFGVVLWEITS----------LAEQPYQGLSNEQ----- 1244 Query: 478 ALAKMVDPAMDGMY---PAKSLSRFADIIALSVQPEPEFRPPISEVVQQL 338 + K V MDG Y P R D++ + Q P+ RP E+V L Sbjct: 1245 -VLKFV---MDGGYLDQPDNCPERVTDLMRMCWQFNPKMRPTFLEIVNLL 1290
>SRK3_SPOLA (P42689) Tyrosine-protein kinase SRK3 (EC 2.7.10.2) (Fragment)| Length = 334 Score = 40.4 bits (93), Expect = 0.005 Identities = 18/37 (48%), Positives = 30/37 (81%), Gaps = 1/37 (2%) Frame = -3 Query: 658 LEYSAPEFAMSGTYTVKSDVYSFGVVMLELLT-GRKP 551 ++++APE A+ +T+KSDV+SFGV++ E++T GR P Sbjct: 226 IKWTAPEAALYNRFTIKSDVWSFGVLISEIVTHGRMP 262
>ITK_MOUSE (Q03526) Tyrosine-protein kinase ITK/TSK (EC 2.7.10.2)| (T-cell-specific kinase) (IL-2-inducible T-cell kinase) (Kinase EMT) (Kinase TLK) Length = 625 Score = 40.4 bits (93), Expect = 0.005 Identities = 28/112 (25%), Positives = 54/112 (48%) Frame = -3 Query: 658 LEYSAPEFAMSGTYTVKSDVYSFGVVMLELLTGRKPLDRSRERSEQSLVGWATPQLHDID 479 +++++PE Y+ KSDV+SFGV+M E+ + K +R SE + DI Sbjct: 527 VKWASPEVFSFSRYSSKSDVWSFGVLMWEVFSEGKIPYENRSNSE---------VVEDIS 577 Query: 478 ALAKMVDPAMDGMYPAKSLSRFADIIALSVQPEPEFRPPISEVVQQLVRLMQ 323 ++ P + + + ++ + +PE RPP S+++ QL + + Sbjct: 578 TGFRLYKPRLASCHVYQIMNH-------CWKEKPEDRPPFSQLLSQLAEIAE 622
>PKN2_MYXXA (P54736) Serine/threonine-protein kinase pkn2 (EC 2.7.11.1)| Length = 830 Score = 40.0 bits (92), Expect = 0.006 Identities = 34/130 (26%), Positives = 55/130 (42%) Frame = -3 Query: 655 EYSAPEFAMSGTYTVKSDVYSFGVVMLELLTGRKPLDRSRERSEQSLVGWATPQLHDIDA 476 EY +PE A+ +SD+YSFGV+ +L+GR P D R+ S A P D Sbjct: 182 EYLSPEQAVGAKVDTRSDLYSFGVLTYRVLSGRLPFDGPLPRNFLSQHASAAPLPLD--- 238 Query: 475 LAKMVDPAMDGMYPAKSLSRFADIIALSVQPEPEFRPPISEVVQQLVRLMQRASMLRRQS 296 A +LSR+ +++L ++RL+++ + R QS Sbjct: 239 ------------RAAPTLSRYVGLLSL------------------VMRLLEKDASKRPQS 268 Query: 295 GDDLGSSYRA 266 +L + A Sbjct: 269 AHELADALAA 278
>M3KL4_HUMAN (Q5TCX8) Mitogen-activated protein kinase kinase kinase (EC| 2.7.11.25) (Mixed lineage kinase 4) Length = 1036 Score = 40.0 bits (92), Expect = 0.006 Identities = 29/111 (26%), Positives = 49/111 (44%), Gaps = 3/111 (2%) Frame = -3 Query: 652 YSAPEFAMSGTYTVKSDVYSFGVVMLELLTGRKPLDRSRERSEQSLVGWATPQLHDIDAL 473 + APE S ++ SD++S+GV++ ELLTG P ID L Sbjct: 310 WMAPEVIKSSLFSKGSDIWSYGVLLWELLTGEVP-------------------YRGIDGL 350 Query: 472 AKMVDPAMDGM---YPAKSLSRFADIIALSVQPEPEFRPPISEVVQQLVRL 329 A A++ + P+ FA ++ Q +P RP + +++QL + Sbjct: 351 AVAYGVAVNKLTLPIPSTCPEPFAKLMKECWQQDPHIRPSFALILEQLTAI 401
>TNI3K_RAT (Q7TQP6) Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1)| (TNNI3-interacting kinase) (Cardiac ankyrin repeat kinase) Length = 834 Score = 40.0 bits (92), Expect = 0.006 Identities = 33/129 (25%), Positives = 52/129 (40%), Gaps = 1/129 (0%) Frame = -3 Query: 661 HLEYSAPE-FAMSGTYTVKSDVYSFGVVMLELLTGRKPLDRSRERSEQSLVGWATPQLHD 485 +L + APE F YT+K+DV+S+ + + ELLTG P + P Sbjct: 626 NLRWMAPEVFTQCTRYTIKADVFSYSLCLWELLTGEIPFAHLK------------PAAAA 673 Query: 484 IDALAKMVDPAMDGMYPAKSLSRFADIIALSVQPEPEFRPPISEVVQQLVRLMQRASMLR 305 D + P + P + ++ PE RP SEVV +L + ++ Sbjct: 674 ADMAYHHIRPPIGYSIP----KPISSLLIRGWNACPEGRPEFSEVVSKLEECLCNVELMS 729 Query: 304 RQSGDDLGS 278 S + GS Sbjct: 730 PASSNSSGS 738
>UNC51_CAEEL (Q23023) Serine/threonine-protein kinase unc-51 (EC 2.7.11.1)| (Uncoordinated protein 51) Length = 856 Score = 40.0 bits (92), Expect = 0.006 Identities = 21/69 (30%), Positives = 35/69 (50%), Gaps = 12/69 (17%) Frame = -3 Query: 652 YSAPEFAMSGTYTVKSDVYSFGVVMLELLTGRKPL------------DRSRERSEQSLVG 509 Y APE MS Y K+D++S G ++ + LTG+ P +++RE ++ Sbjct: 184 YMAPEVIMSMQYDAKADLWSIGTILFQCLTGKAPFVAQTPPQLKAYYEKTRE-LRPNIPE 242 Query: 508 WATPQLHDI 482 W +P L D+ Sbjct: 243 WCSPNLRDL 251
>BLK_HUMAN (P51451) Tyrosine-protein kinase BLK (EC 2.7.10.2) (B lymphocyte| kinase) (p55-BLK) Length = 504 Score = 39.7 bits (91), Expect = 0.008 Identities = 17/37 (45%), Positives = 30/37 (81%), Gaps = 1/37 (2%) Frame = -3 Query: 658 LEYSAPEFAMSGTYTVKSDVYSFGVVMLELLT-GRKP 551 ++++APE G +T+K+DV+SFGV+++E++T GR P Sbjct: 398 IKWTAPEAIHFGVFTIKADVWSFGVLLMEVVTYGRVP 434
>CCAMK_MEDTR (Q6RET7) Calcium and calcium/calmodulin-dependent| serine/threonine-protein kinase DMI-3 (EC 2.7.11.17) (Does not make infections protein 3) (CCaMK DMI3) (MtCCaMK) Length = 523 Score = 39.7 bits (91), Expect = 0.008 Identities = 17/49 (34%), Positives = 28/49 (57%) Frame = -3 Query: 658 LEYSAPEFAMSGTYTVKSDVYSFGVVMLELLTGRKPLDRSRERSEQSLV 512 ++Y +PE G T KSD++S GV++ LL+G P R +Q ++ Sbjct: 212 IDYVSPEALSQGKITTKSDMWSLGVILYILLSGYPPFIAQNNRQKQQMI 260
>SPK1_DUGTI (P42687) Tyrosine-protein kinase SPK-1 (EC 2.7.10.2)| Length = 497 Score = 39.7 bits (91), Expect = 0.008 Identities = 17/31 (54%), Positives = 25/31 (80%) Frame = -3 Query: 655 EYSAPEFAMSGTYTVKSDVYSFGVVMLELLT 563 +++APE A S +T KSDV+S+G+VM E+LT Sbjct: 384 KWTAPEAAKSKVFTSKSDVWSYGIVMFEILT 414
>INSR_RAT (P15127) Insulin receptor precursor (EC 2.7.10.1) (IR) [Contains:| Insulin receptor alpha subunit; Insulin receptor beta subunit] Length = 1383 Score = 39.7 bits (91), Expect = 0.008 Identities = 32/110 (29%), Positives = 49/110 (44%), Gaps = 3/110 (2%) Frame = -3 Query: 658 LEYSAPEFAMSGTYTVKSDVYSFGVVMLELLTGRKPLDRSRERSEQSLVGWATPQLHDID 479 + + +PE G +T SD++SFGVV+ E+ + +EQ G + Q Sbjct: 1201 VRWMSPESLKDGVFTASSDMWSFGVVLWEITS----------LAEQPYQGLSNEQ----- 1245 Query: 478 ALAKMVDPAMDGMY---PAKSLSRFADIIALSVQPEPEFRPPISEVVQQL 338 + K V MDG Y P R D++ + Q P+ RP E+V L Sbjct: 1246 -VLKFV---MDGGYLDPPDNCPERLTDLMRMCWQFNPKMRPTFLEIVNLL 1291
>INSR_MOUSE (P15208) Insulin receptor precursor (EC 2.7.10.1) (IR) [Contains:| Insulin receptor alpha subunit; Insulin receptor beta subunit] Length = 1372 Score = 39.7 bits (91), Expect = 0.008 Identities = 32/110 (29%), Positives = 49/110 (44%), Gaps = 3/110 (2%) Frame = -3 Query: 658 LEYSAPEFAMSGTYTVKSDVYSFGVVMLELLTGRKPLDRSRERSEQSLVGWATPQLHDID 479 + + +PE G +T SD++SFGVV+ E+ + +EQ G + Q Sbjct: 1190 VRWMSPESLKDGVFTASSDMWSFGVVLWEITS----------LAEQPYQGLSNEQ----- 1234 Query: 478 ALAKMVDPAMDGMY---PAKSLSRFADIIALSVQPEPEFRPPISEVVQQL 338 + K V MDG Y P R D++ + Q P+ RP E+V L Sbjct: 1235 -VLKFV---MDGGYLDPPDNCPERLTDLMRMCWQFNPKMRPTFLEIVNLL 1280
>CCAMK_PEA (Q6RET6) Calcium and calcium/calmodulin-dependent| serine/threonine-protein kinase (EC 2.7.11.17) (PsCCaMK) (Ps-SYM9) (Fragment) Length = 527 Score = 39.7 bits (91), Expect = 0.008 Identities = 17/49 (34%), Positives = 28/49 (57%) Frame = -3 Query: 658 LEYSAPEFAMSGTYTVKSDVYSFGVVMLELLTGRKPLDRSRERSEQSLV 512 ++Y +PE G T KSD++S GV++ LL+G P R +Q ++ Sbjct: 220 IDYVSPEALSQGKITTKSDMWSLGVILYILLSGYPPFIAQNNRQKQQMI 268
>PBS2_YEAST (P08018) MAP kinase kinase PBS2 (EC 2.7.12.2) (Polymyxin B| resistance protein 2) (Suppressor of fluoride sensitivity 4) Length = 668 Score = 39.7 bits (91), Expect = 0.008 Identities = 32/110 (29%), Positives = 49/110 (44%), Gaps = 7/110 (6%) Frame = -3 Query: 652 YSAPEFAMS-----GTYTVKSDVYSFGVVMLELLTGRKPLDRSRERSEQSLVGWATPQLH 488 Y APE S TYTV+SD++S G+ +LE+ GR P P+ + Sbjct: 525 YMAPERIKSLNPDRATYTVQSDIWSLGLSILEMALGRYPY---------------PPETY 569 Query: 487 D--IDALAKMVDPAMDGMYPAKSLSRFADIIALSVQPEPEFRPPISEVVQ 344 D L+ +VD + K S D ++L +Q PE RP + + + Sbjct: 570 DNIFSQLSAIVDGPPPRLPSDKFSSDAQDFVSLCLQKIPERRPTYAALTE 619
>VGFR1_RAT (P53767) Vascular endothelial growth factor receptor 1 precursor (EC| 2.7.10.1) (VEGFR-1) (Tyrosine-protein kinase receptor FLT) (FLT-1) Length = 1336 Score = 39.3 bits (90), Expect = 0.011 Identities = 36/151 (23%), Positives = 66/151 (43%), Gaps = 11/151 (7%) Frame = -3 Query: 658 LEYSAPEFAMSGTYTVKSDVYSFGVVMLELLT-GRKP----------LDRSRERSEQSLV 512 L++ APE Y+ KSDV+S+GV++ E+ + G P R +E Sbjct: 1063 LKWMAPESIFDKVYSTKSDVWSYGVLLWEIFSLGGSPYPGVQMDEDFCSRLKEGMRMRTP 1122 Query: 511 GWATPQLHDIDALAKMVDPAMDGMYPAKSLSRFADIIALSVQPEPEFRPPISEVVQQLVR 332 +ATP+++ I DP + A+ + + D++ +VQ + + P++ + L R Sbjct: 1123 EYATPEIYQIMLDCWHKDPKERPRF-AELVEKLGDLLQANVQQDGKDYIPLNAI---LTR 1178 Query: 331 LMQRASMLRRQSGDDLGSSYRAPEREGGASD 239 + S D + P+ G+SD Sbjct: 1179 NSGFTYSVPTFSEDFFKDGFTDPKFHSGSSD 1209
>VGFR1_HUMAN (P17948) Vascular endothelial growth factor receptor 1 precursor (EC| 2.7.10.1) (VEGFR-1) (Vascular permeability factor receptor) (Tyrosine-protein kinase receptor FLT) (Flt-1) (Tyrosine-protein kinase FRT) (Fms-like tyrosine kinase 1) Length = 1338 Score = 39.3 bits (90), Expect = 0.011 Identities = 37/151 (24%), Positives = 65/151 (43%), Gaps = 11/151 (7%) Frame = -3 Query: 658 LEYSAPEFAMSGTYTVKSDVYSFGVVMLELLT-GRKP----------LDRSRERSEQSLV 512 L++ APE Y+ KSDV+S+GV++ E+ + G P R RE Sbjct: 1063 LKWMAPESIFDKIYSTKSDVWSYGVLLWEIFSLGGSPYPGVQMDEDFCSRLREGMRMRAP 1122 Query: 511 GWATPQLHDIDALAKMVDPAMDGMYPAKSLSRFADIIALSVQPEPEFRPPISEVVQQLVR 332 ++TP+++ I DP + A+ + + D++ +VQ + + PI+ ++ Sbjct: 1123 EYSTPEIYQIMLDCWHRDPKERPRF-AELVEKLGDLLQANVQQDGKDYIPINAILTGNSG 1181 Query: 331 LMQRASMLRRQSGDDLGSSYRAPEREGGASD 239 S D S AP+ G+SD Sbjct: 1182 FTYSTPAF---SEDFFKESISAPKFNSGSSD 1209
>RAF1_XENLA (P09560) RAF proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (C-RAF) Length = 638 Score = 39.3 bits (90), Expect = 0.011 Identities = 32/129 (24%), Positives = 58/129 (44%) Frame = -3 Query: 619 YTVKSDVYSFGVVMLELLTGRKPLDRSRERSEQSLVGWATPQLHDIDALAKMVDPAMDGM 440 ++ +SDVYS+G+V+ EL+TG P R+R + + + D+ L K AM Sbjct: 516 FSFQSDVYSYGIVLYELMTGELPYSHIRDRDQIIFLVGRGGVVPDLSKLYKNCPKAM--- 572 Query: 439 YPAKSLSRFADIIALSVQPEPEFRPPISEVVQQLVRLMQRASMLRRQSGDDLGSSYRAPE 260 ++A S++ + RP +++ + L + R + + S +RA Sbjct: 573 ---------KRLVADSIKKLRDERPLFPQILSSIELLQHSLPKINRSALEP--SLHRAAH 621 Query: 259 REGGASDAL 233 E +S AL Sbjct: 622 TEDISSCAL 630
>CHK1_CAEEL (Q9N3Z3) Serine/threonine-protein kinase chk-1 (EC 2.7.11.1)| Length = 503 Score = 39.3 bits (90), Expect = 0.011 Identities = 21/52 (40%), Positives = 31/52 (59%), Gaps = 1/52 (1%) Frame = -3 Query: 658 LEYSAPEFAMSGTYTVKS-DVYSFGVVMLELLTGRKPLDRSRERSEQSLVGW 506 + Y+APE Y DV+S G+V++ +LTG P DR+ + S QS +GW Sbjct: 191 IPYAAPELCAGKKYRGPPVDVWSSGIVLIAMLTGELPWDRASDAS-QSYMGW 241
>M3LK7_DROME (P83104) Putative mitogen-activated protein kinase kinase kinase| 7-like (EC 2.7.11.25) Length = 393 Score = 39.3 bits (90), Expect = 0.011 Identities = 19/46 (41%), Positives = 25/46 (54%) Frame = -3 Query: 658 LEYSAPEFAMSGTYTVKSDVYSFGVVMLELLTGRKPLDRSRERSEQ 521 L Y APE YT K DVYSFG+++ EL+T + P + Q Sbjct: 170 LRYMAPEAIKHLKYTAKCDVYSFGIMLWELMTRQLPYSHLENPNSQ 215
>PKSC_STRCO (Q9S2C0) Serine/threonine protein kinase pksC (EC 2.7.11.1)| Length = 556 Score = 38.9 bits (89), Expect = 0.014 Identities = 26/106 (24%), Positives = 52/106 (49%), Gaps = 2/106 (1%) Frame = -3 Query: 655 EYSAPEFAMSGTYTVKSDVYSFGVVMLELLTGRKPLDRSRERSEQSLVGWATPQLHDI-- 482 +Y +PE A+ +SD+YS G+++ +L+TGR P D + + +A Q + Sbjct: 194 QYLSPEQALGRGVDARSDLYSVGIMLFQLVTGRLPFDADSPLA----IAYAHVQEQPVAP 249 Query: 481 DALAKMVDPAMDGMYPAKSLSRFADIIALSVQPEPEFRPPISEVVQ 344 A+ + + PA+D ++A +++ P R P +E ++ Sbjct: 250 SAVNRALPPAVDA------------LVARALKKNPNERFPSAEAMR 283
>TNI3K_HUMAN (Q59H18) Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1)| (TNNI3-interacting kinase) (Cardiac ankyrin repeat kinase) Length = 936 Score = 38.9 bits (89), Expect = 0.014 Identities = 32/129 (24%), Positives = 52/129 (40%), Gaps = 1/129 (0%) Frame = -3 Query: 661 HLEYSAPE-FAMSGTYTVKSDVYSFGVVMLELLTGRKPLDRSRERSEQSLVGWATPQLHD 485 +L + APE F YT+K+DV+S+ + + E+LTG P + P Sbjct: 728 NLRWMAPEVFTQCTRYTIKADVFSYALCLWEILTGEIPFAHLK------------PAAAA 775 Query: 484 IDALAKMVDPAMDGMYPAKSLSRFADIIALSVQPEPEFRPPISEVVQQLVRLMQRASMLR 305 D + P + P + ++ PE RP SEVV +L + ++ Sbjct: 776 ADMAYHHIRPPIGYSIP----KPISSLLIRGWNACPEGRPEFSEVVMKLEECLCNIELMS 831 Query: 304 RQSGDDLGS 278 S + GS Sbjct: 832 PASSNSSGS 840
>SRC64_DROME (P00528) Tyrosine-protein kinase Src64B (EC 2.7.10.2) (Dsrc64)| Length = 552 Score = 38.9 bits (89), Expect = 0.014 Identities = 21/58 (36%), Positives = 38/58 (65%), Gaps = 3/58 (5%) Frame = -3 Query: 658 LEYSAPEFAMSGTYTVKSDVYSFGVVMLELLT-GRKPLD--RSRERSEQSLVGWATPQ 494 ++++APE + G +++KSDV+S+G++++EL T G+ P SRE E G+ P+ Sbjct: 444 VKWTAPEAIIYGKFSIKSDVWSYGILLMELFTYGQVPYPGMHSREVIENIERGFRMPK 501
>KPEL_DROME (Q05652) Probable serine/threonine-protein kinase pelle (EC| 2.7.11.1) Length = 501 Score = 38.9 bits (89), Expect = 0.014 Identities = 21/54 (38%), Positives = 32/54 (59%), Gaps = 1/54 (1%) Frame = -3 Query: 652 YSAPEFAMSGTYTVKSDVYSFGVVMLELLTGRKPLDRSRE-RSEQSLVGWATPQ 494 Y PEF + DVYSFG+V+LE+ TGR+ DR E ++++L+ + Q Sbjct: 390 YLPPEFRNFRQLSTGVDVYSFGIVLLEVFTGRQVTDRVPENETKKNLLDYVKQQ 443
>MIL_AVIMH (P00531) Serine/threonine-protein kinase transforming protein mil| (EC 2.7.11.1) Length = 380 Score = 38.9 bits (89), Expect = 0.014 Identities = 32/128 (25%), Positives = 56/128 (43%), Gaps = 3/128 (2%) Frame = -3 Query: 628 SGTYTVKSDVYSFGVVMLELLTGRKPLDRSRERSEQSLV---GWATPQLHDIDALAKMVD 458 S ++ +SDVYS+G+V+ EL+TG P R + + G+A+P D+ L K Sbjct: 255 SNPFSFQSDVYSYGIVLYELMTGELPYSHINNRDQIIFMVGRGYASP---DLSKLYKNCP 311 Query: 457 PAMDGMYPAKSLSRFADIIALSVQPEPEFRPPISEVVQQLVRLMQRASMLRRQSGDDLGS 278 AM ++A ++ E RP +++ + L + R + + S Sbjct: 312 KAM------------KRLVADCLKKVREERPLFPQILSSIALLQHSLPKINRSASEP--S 357 Query: 277 SYRAPERE 254 +RA E Sbjct: 358 LHRASHTE 365
>SRK2_SPOLA (P42688) Tyrosine-protein kinase SRK2 (EC 2.7.10.2) (Fragment)| Length = 362 Score = 38.9 bits (89), Expect = 0.014 Identities = 17/37 (45%), Positives = 30/37 (81%), Gaps = 1/37 (2%) Frame = -3 Query: 658 LEYSAPEFAMSGTYTVKSDVYSFGVVMLELLT-GRKP 551 ++++APE A+ +++KSDV+SFG+++ EL+T GR P Sbjct: 254 IKWTAPEAALFNRFSIKSDVWSFGILITELVTYGRIP 290
>KYK1_DICDI (P18160) Non-receptor tyrosine kinase spore lysis A (EC 2.7.10.2)| (Tyrosine-protein kinase 1) Length = 1584 Score = 38.9 bits (89), Expect = 0.014 Identities = 26/107 (24%), Positives = 47/107 (43%) Frame = -3 Query: 658 LEYSAPEFAMSGTYTVKSDVYSFGVVMLELLTGRKPLDRSRERSEQSLVGWATPQLHDID 479 + Y APE + + KSDVYS+G+V+ ELLT +P + L + + + Sbjct: 1469 IPYMAPEVFKGDSNSEKSDVYSYGMVLFELLTSDEPQQDMKPMKMAHLAAYESYR----- 1523 Query: 478 ALAKMVDPAMDGMYPAKSLSRFADIIALSVQPEPEFRPPISEVVQQL 338 P + P + S++ +I+ P+ RP +++ L Sbjct: 1524 -------PPI----PLTTSSKWKEILTQCWDSNPDSRPTFKQIIVHL 1559
>HCK_MACFA (Q95M30) Tyrosine-protein kinase HCK (EC 2.7.10.2) (p56-HCK)| (Hemopoietic cell kinase) Length = 503 Score = 38.9 bits (89), Expect = 0.014 Identities = 17/37 (45%), Positives = 30/37 (81%), Gaps = 1/37 (2%) Frame = -3 Query: 658 LEYSAPEFAMSGTYTVKSDVYSFGVVMLELLT-GRKP 551 ++++APE G+ T+KSDV+SFG++++E++T GR P Sbjct: 398 IKWTAPEAINFGSSTIKSDVWSFGILLMEIVTYGRIP 434
>PDK1L_BRARE (Q32PP3) Serine/threonine-protein kinase pdik1l (EC 2.7.11.1)| Length = 341 Score = 38.9 bits (89), Expect = 0.014 Identities = 34/116 (29%), Positives = 57/116 (49%), Gaps = 5/116 (4%) Frame = -3 Query: 652 YSAPEFAMSGTYTVKSDVYSFGVVMLELLTGRKPLDRSRERSEQSLVGWATPQLHDIDAL 473 Y APE G YT K+D+++ GV++ ++ +D +++ L+G Q DI L Sbjct: 224 YMAPE-VWEGHYTAKADIFALGVIIWAMVERITFVD---VETQKELLGSYVQQGEDIVPL 279 Query: 472 --AKMVDPAMDGMYPAKSLSRFA---DIIALSVQPEPEFRPPISEVVQQLVRLMQR 320 A + +P M+ PA+ S A +I + P+ RP E+ +LVR+ R Sbjct: 280 GEALLENPKMELNIPARKKSMNASMKQLIREMLSANPQERPDAFELELRLVRIACR 335
>KS6A2_MOUSE (Q9WUT3) Ribosomal protein S6 kinase alpha-2 (EC 2.7.11.1)| (S6K-alpha 2) (90 kDa ribosomal protein S6 kinase 2) (p90-RSK 2) (Ribosomal S6 kinase 3) (RSK-3) (pp90RSK3) (Protein-tyrosine kinase Mpk-9) (MAP kinase-activated protein kinase 1c) (M Length = 733 Score = 38.9 bits (89), Expect = 0.014 Identities = 18/49 (36%), Positives = 27/49 (55%) Frame = -3 Query: 658 LEYSAPEFAMSGTYTVKSDVYSFGVVMLELLTGRKPLDRSRERSEQSLV 512 +EY APE +T +D +SFGV+M E+LTG P + +L+ Sbjct: 223 IEYMAPEVVNRRGHTQSADWWSFGVLMFEMLTGSLPFQGKDRKETMALI 271
>KS6A2_HUMAN (Q15349) Ribosomal protein S6 kinase alpha-2 (EC 2.7.11.1)| (S6K-alpha 2) (90 kDa ribosomal protein S6 kinase 2) (p90-RSK 2) (Ribosomal S6 kinase 3) (RSK-3) (pp90RSK3) (MAP kinase-activated protein kinase 1c) (MAPKAPK1C) Length = 733 Score = 38.9 bits (89), Expect = 0.014 Identities = 18/49 (36%), Positives = 27/49 (55%) Frame = -3 Query: 658 LEYSAPEFAMSGTYTVKSDVYSFGVVMLELLTGRKPLDRSRERSEQSLV 512 +EY APE +T +D +SFGV+M E+LTG P + +L+ Sbjct: 223 IEYMAPEVVNRRGHTQSADWWSFGVLMFEMLTGSLPFQGKDRKETMALI 271
>MP2K6_HUMAN (P52564) Dual specificity mitogen-activated protein kinase kinase 6| (EC 2.7.12.2) (MAP kinase kinase 6) (MAPKK 6) (MAPK/ERK kinase 6) (SAPKK3) Length = 334 Score = 38.9 bits (89), Expect = 0.014 Identities = 28/100 (28%), Positives = 44/100 (44%) Frame = -3 Query: 643 PEFAMSGTYTVKSDVYSFGVVMLELLTGRKPLDRSRERSEQSLVGWATPQLHDIDALAKM 464 PE G Y+VKSD++S G+ M+EL R P D W TP L ++ Sbjct: 227 PELNQKG-YSVKSDIWSLGITMIELAILRFPYD-----------SWGTP----FQQLKQV 270 Query: 463 VDPAMDGMYPAKSLSRFADIIALSVQPEPEFRPPISEVVQ 344 V+ + K + F D + ++ + RP E++Q Sbjct: 271 VEEPSPQLPADKFSAEFVDFTSQCLKKNSKERPTYPELMQ 310
>LRRK1_MOUSE (Q3UHC2) Leucine-rich repeat serine/threonine-protein kinase 1 (EC| 2.7.11.1) Length = 2014 Score = 38.5 bits (88), Expect = 0.018 Identities = 29/105 (27%), Positives = 45/105 (42%) Frame = -3 Query: 652 YSAPEFAMSGTYTVKSDVYSFGVVMLELLTGRKPLDRSRERSEQSLVGWATPQLHDIDAL 473 Y APE Y K D++S+G+V+ ELL+G++P QL + L Sbjct: 1430 YQAPEIRPRIVYDEKVDMFSYGMVLYELLSGQRP-------------ALGHHQLQIVKKL 1476 Query: 472 AKMVDPAMDGMYPAKSLSRFADIIALSVQPEPEFRPPISEVVQQL 338 +K + P + G R ++ +PE RP VV Q+ Sbjct: 1477 SKGIRPVL-GQPEEVQFHRLQALMMECWDTKPEKRPLALSVVSQM 1520
>VGFR2_BRARE (Q8AXB3) Vascular endothelial growth factor receptor 2 precursor (EC| 2.7.10.1) (VEGFR-2) (Receptor tyrosine kinase flk-1) Length = 1302 Score = 38.5 bits (88), Expect = 0.018 Identities = 32/112 (28%), Positives = 46/112 (41%) Frame = -3 Query: 658 LEYSAPEFAMSGTYTVKSDVYSFGVVMLELLTGRKPLDRSRERSEQSLVGWATPQLHDID 479 L++ APE YT +SDV+SFGV+M E+ SL P LH + Sbjct: 1044 LKWMAPEAIFDKIYTTQSDVWSFGVLMWEIF---------------SLGASPYPGLHIDE 1088 Query: 478 ALAKMVDPAMDGMYPAKSLSRFADIIALSVQPEPEFRPPISEVVQQLVRLMQ 323 + P S S + EP RP +E+V++L L+Q Sbjct: 1089 EFCCRLKEGTRMKAPEYSSSEIYQTMLDCWHGEPSQRPTFTELVERLGDLLQ 1140
>INSRR_CAVPO (P14617) Insulin receptor-related protein precursor (EC 2.7.10.1)| (IRR) (IR-related receptor) [Contains: Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain] Length = 1300 Score = 38.5 bits (88), Expect = 0.018 Identities = 31/137 (22%), Positives = 61/137 (44%) Frame = -3 Query: 658 LEYSAPEFAMSGTYTVKSDVYSFGVVMLELLTGRKPLDRSRERSEQSLVGWATPQLHDID 479 + + APE G +T SDV+SFGVV+ E++T +EQ G + Q+ Sbjct: 1156 VRWMAPESLKDGIFTTHSDVWSFGVVLWEIVT----------LAEQPYQGLSNEQVLKFV 1205 Query: 478 ALAKMVDPAMDGMYPAKSLSRFADIIALSVQPEPEFRPPISEVVQQLVRLMQRASMLRRQ 299 +++ D + + ++++ Q P RP ++++ + + ++ + L Sbjct: 1206 MDGGVLEELEDCPH------QLQELMSSCWQQNPRLRPTFTQILNSIQKELRPSFRLL-- 1257 Query: 298 SGDDLGSSYRAPEREGG 248 S Y +PE +GG Sbjct: 1258 ------SFYHSPECQGG 1268
>RAF1_RAT (P11345) RAF proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (Raf-1) (C-RAF) (cRaf) Length = 648 Score = 38.5 bits (88), Expect = 0.018 Identities = 32/125 (25%), Positives = 55/125 (44%), Gaps = 3/125 (2%) Frame = -3 Query: 619 YTVKSDVYSFGVVMLELLTGRKPLDRSRERSEQSLV---GWATPQLHDIDALAKMVDPAM 449 ++ +SDVYS+G+V+ EL+TG P R + + G+A+P D+ L K AM Sbjct: 525 FSFQSDVYSYGIVLYELMTGELPYSHINNRDQIIFMVGRGYASP---DLSRLYKNCPKAM 581 Query: 448 DGMYPAKSLSRFADIIALSVQPEPEFRPPISEVVQQLVRLMQRASMLRRQSGDDLGSSYR 269 ++A V+ E RP +++ + L + R + + S +R Sbjct: 582 ------------KRLVADCVKKVKEERPLFPQILSSIELLQHSLPKINRSASEP--SLHR 627 Query: 268 APERE 254 A E Sbjct: 628 AAHTE 632
>RAF1_HUMAN (P04049) RAF proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (Raf-1) (C-RAF) (cRaf) Length = 648 Score = 38.5 bits (88), Expect = 0.018 Identities = 32/125 (25%), Positives = 55/125 (44%), Gaps = 3/125 (2%) Frame = -3 Query: 619 YTVKSDVYSFGVVMLELLTGRKPLDRSRERSEQSLV---GWATPQLHDIDALAKMVDPAM 449 ++ +SDVYS+G+V+ EL+TG P R + + G+A+P D+ L K AM Sbjct: 525 FSFQSDVYSYGIVLYELMTGELPYSHINNRDQIIFMVGRGYASP---DLSKLYKNCPKAM 581 Query: 448 DGMYPAKSLSRFADIIALSVQPEPEFRPPISEVVQQLVRLMQRASMLRRQSGDDLGSSYR 269 ++A V+ E RP +++ + L + R + + S +R Sbjct: 582 ------------KRLVADCVKKVKEERPLFPQILSSIELLQHSLPKINRSASEP--SLHR 627 Query: 268 APERE 254 A E Sbjct: 628 AAHTE 632
>E2AK1_HUMAN (Q9BQI3) Eukaryotic translation initiation factor 2-alpha kinase 1| (EC 2.7.11.1) (Heme-regulated eukaryotic initiation factor eIF-2-alpha kinase) (Heme-regulated inhibitor) (Heme-controlled repressor) (HCR) (Hemin-sensitive initiation factor Length = 630 Score = 38.5 bits (88), Expect = 0.018 Identities = 24/54 (44%), Positives = 30/54 (55%) Frame = -3 Query: 652 YSAPEFAMSGTYTVKSDVYSFGVVMLELLTGRKPLDRSRERSEQSLVGWATPQL 491 Y++PE Y KSD+YS GVV+LEL +P ER+E L G T QL Sbjct: 496 YASPEQLEGSEYDAKSDMYSLGVVLLELF---QPFGTEMERAE-VLTGLRTGQL 545
>VGFR1_MOUSE (P35969) Vascular endothelial growth factor receptor 1 precursor (EC| 2.7.10.1) (VEGFR-1) (Tyrosine-protein kinase receptor FLT) (FLT-1) (Embryonic receptor kinase 2) Length = 1333 Score = 38.5 bits (88), Expect = 0.018 Identities = 28/115 (24%), Positives = 55/115 (47%), Gaps = 11/115 (9%) Frame = -3 Query: 658 LEYSAPEFAMSGTYTVKSDVYSFGVVMLELLT-GRKP----------LDRSRERSEQSLV 512 L++ APE Y+ KSDV+S+GV++ E+ + G P R +E Sbjct: 1063 LKWMAPESIFDKVYSTKSDVWSYGVLLWEIFSLGGSPYPGVQMDEDFCSRLKEGMRMRTP 1122 Query: 511 GWATPQLHDIDALAKMVDPAMDGMYPAKSLSRFADIIALSVQPEPEFRPPISEVV 347 +ATP+++ I DP + A+ + + D++ +VQ + + P++ ++ Sbjct: 1123 EYATPEIYQIMLDCWHKDPKERPRF-AELVEKLGDLLQANVQQDGKDYIPLNAIL 1176
>PK1_STRTO (Q9KIG4) Serine/threonine-protein kinase PK-1 (EC 2.7.11.1)| (stoPK-1) Length = 641 Score = 38.5 bits (88), Expect = 0.018 Identities = 35/124 (28%), Positives = 52/124 (41%) Frame = -3 Query: 658 LEYSAPEFAMSGTYTVKSDVYSFGVVMLELLTGRKPLDRSRERSEQSLVGWATPQLHDID 479 + Y APE GT + DVY+ G+++ E+LTG KP D ++V + LHD Sbjct: 180 VSYLAPEQIEHGTADPRVDVYACGILLYEMLTGEKPHD----GDSPAIVLY--KHLHDDV 233 Query: 478 ALAKMVDPAMDGMYPAKSLSRFADIIALSVQPEPEFRPPISEVVQQLVRLMQRASMLRRQ 299 P M +++A + PE RP V L+ RA R + Sbjct: 234 PPPSAAVPGM--------AYELDELVASATARGPEVRP------HDAVALLARARDARAR 279 Query: 298 SGDD 287 GD+ Sbjct: 280 LGDE 283
>HUNK_MOUSE (O88866) Hormonally up-regulated neu tumor-associated kinase (EC| 2.7.11.1) (Serine/threonine-protein kinase MAK-V) Length = 714 Score = 38.5 bits (88), Expect = 0.018 Identities = 31/103 (30%), Positives = 47/103 (45%), Gaps = 1/103 (0%) Frame = -3 Query: 652 YSAPEFAMSGTYTVKSDVYSFGVVMLELLTGRKPLDRSRERSEQSLVGWATPQLHDIDAL 473 Y+APE Y K DV+S GV M +LTG P T + + AL Sbjct: 229 YAAPELLARKKYGPKIDVWSIGVNMYAMLTGTLPF---------------TVEPFSLRAL 273 Query: 472 -AKMVDPAMDGMYPAKSLSRFADIIALSVQPEPEFRPPISEVV 347 KMVD AM+ + P + + + + ++P+P RP I + + Sbjct: 274 YQKMVDKAMNPL-PTQLSTGAVNFLRSLLEPDPVKRPNIQQAL 315
>ICL1_KLULA (Q6CWQ4) Spindle assembly checkpoint kinase (EC 2.7.11.1) (Aurora| kinase) Length = 361 Score = 38.1 bits (87), Expect = 0.024 Identities = 28/104 (26%), Positives = 46/104 (44%), Gaps = 1/104 (0%) Frame = -3 Query: 658 LEYSAPEFAMSGTYTVKSDVYSFGVVMLELLTGRKPLDR-SRERSEQSLVGWATPQLHDI 482 ++Y +PE S Y K DV++ GV+ ELL G P + ++E + + ++ Sbjct: 261 IDYLSPELIKSREYNNKVDVWALGVLTYELLVGSPPFEEDTKEMTYRRIL---------- 310 Query: 481 DALAKMVDPAMDGMYPAKSLSRFADIIALSVQPEPEFRPPISEV 350 D +P + D+I +Q EP R P+SEV Sbjct: 311 ---------RCDLKFPLNVSPQARDLIVRLLQFEPSKRIPLSEV 345
>TNI3K_MOUSE (Q5GIG6) Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1)| (TNNI3-interacting kinase) (Cardiac ankyrin repeat kinase) Length = 833 Score = 38.1 bits (87), Expect = 0.024 Identities = 32/129 (24%), Positives = 52/129 (40%), Gaps = 1/129 (0%) Frame = -3 Query: 661 HLEYSAPE-FAMSGTYTVKSDVYSFGVVMLELLTGRKPLDRSRERSEQSLVGWATPQLHD 485 +L + APE F YT+K+DV+S+ + + ELL G P + P Sbjct: 625 NLRWMAPEVFTQCTRYTIKADVFSYALCLWELLIGEIPFAHLK------------PAAAA 672 Query: 484 IDALAKMVDPAMDGMYPAKSLSRFADIIALSVQPEPEFRPPISEVVQQLVRLMQRASMLR 305 D + P + P + ++ PE RP SEVV++L + ++ Sbjct: 673 ADMAYHHIRPPIGYSIP----KPISSLLMRGWNACPEGRPEFSEVVRKLEECLCNVELMS 728 Query: 304 RQSGDDLGS 278 S + GS Sbjct: 729 PASSNSSGS 737
>STE7_YEAST (P06784) Serine/threonine-protein kinase STE7 (EC 2.7.12.2)| Length = 515 Score = 38.1 bits (87), Expect = 0.024 Identities = 15/35 (42%), Positives = 24/35 (68%) Frame = -3 Query: 652 YSAPEFAMSGTYTVKSDVYSFGVVMLELLTGRKPL 548 Y +PE Y++K DV+S G++++EL+TG PL Sbjct: 370 YMSPERIQGNVYSIKGDVWSLGLMIIELVTGEFPL 404
>KKK1_YEAST (P34244) Probable serine/threonine-protein kinase YKL101W (EC| 2.7.11.1) Length = 1518 Score = 38.1 bits (87), Expect = 0.024 Identities = 36/139 (25%), Positives = 58/139 (41%), Gaps = 16/139 (11%) Frame = -3 Query: 652 YSAPEFAMSGTYTV-KSDVYSFGVVMLELLTGRKPLDRSRERSEQSLVGWATPQLHDIDA 476 Y++PE M Y SDV+S G+V+ LLTG P + D Sbjct: 280 YASPEIVMGRPYHGGPSDVWSCGIVLFALLTGHLPFND--------------------DN 319 Query: 475 LAKMVDPAMDGMY--PAKSLSRFADIIALSVQPEPEFRPPISEV-------------VQQ 341 + K++ G Y P+ S D+I+ + +PE R E+ V + Sbjct: 320 IKKLLLKVQSGKYQMPSNLSSEARDLISKILVIDPEKRITTQEILKHPLIKKYDDLPVNK 379 Query: 340 LVRLMQRASMLRRQSGDDL 284 ++R M++ +M R +S DL Sbjct: 380 VLRKMRKDNMARGKSNSDL 398
>ROS_HUMAN (P08922) Proto-oncogene tyrosine-protein kinase ROS precursor (EC| 2.7.10.1) (c-ros-1) Length = 2347 Score = 38.1 bits (87), Expect = 0.024 Identities = 17/37 (45%), Positives = 27/37 (72%), Gaps = 1/37 (2%) Frame = -3 Query: 658 LEYSAPEFAMSGTYTVKSDVYSFGVVMLELLT-GRKP 551 + + APE M G +T +SDV+SFG+++ E+LT G +P Sbjct: 2125 VRWMAPESLMDGIFTTQSDVWSFGILIWEILTLGHQP 2161
>PKN2_COREF (Q8FUI4) Serine/threonine protein kinases drp72 (EC 2.7.11.1)| Length = 520 Score = 38.1 bits (87), Expect = 0.024 Identities = 31/108 (28%), Positives = 46/108 (42%), Gaps = 9/108 (8%) Frame = -3 Query: 655 EYSAPEFAMSGTYTVKSDVYSFGVVMLELLTGRKPLDRSRERSEQ-SLVGWATPQL---- 491 +Y +PE A T SDVYS GVV E+L+GR+P S + + A PQ+ Sbjct: 189 QYVSPEQAQGHQVTPASDVYSLGVVGYEMLSGRRPFTGDSSVSVAIAHINEAPPQMPTSV 248 Query: 490 ----HDIDALAKMVDPAMDGMYPAKSLSRFADIIALSVQPEPEFRPPI 359 ++ +A DPA L+R + L +P P + Sbjct: 249 SAQARELIGIALRKDPAR-RFADGNELARAVSAVRLGNRPPQPHSPAV 295
>JAK3_HUMAN (P52333) Tyrosine-protein kinase JAK3 (EC 2.7.10.2) (Janus kinase 3)| (JAK-3) (Leukocyte janus kinase) (L-JAK) Length = 1124 Score = 38.1 bits (87), Expect = 0.024 Identities = 31/106 (29%), Positives = 51/106 (48%), Gaps = 3/106 (2%) Frame = -3 Query: 646 APEFAMSGTYTVKSDVYSFGVVMLELLTGRKPLDRSRERSEQSLVGWATPQLHDIDALAK 467 APE ++ +SDV+SFGVV+ EL T D+S S + L + D+ AL + Sbjct: 995 APESLSDNIFSRQSDVWSFGVVLYELFT---YCDKSCSPSAEFLRMMGCER--DVPALCR 1049 Query: 466 MVDPAMDGM---YPAKSLSRFADIIALSVQPEPEFRPPISEVVQQL 338 +++ +G P + +++ L P P+ RP S + QL Sbjct: 1050 LLELLEEGQRLPAPPACPAEVHELMKLCWAPSPQDRPSFSALGPQL 1095
>EPHB6_MOUSE (O08644) Ephrin type-B receptor 6 precursor (Tyrosine-protein| kinase-defective receptor EPH-6) (MEP) Length = 1014 Score = 38.1 bits (87), Expect = 0.024 Identities = 17/37 (45%), Positives = 26/37 (70%), Gaps = 1/37 (2%) Frame = -3 Query: 658 LEYSAPEFAMSGTYTVKSDVYSFGVVMLELLT-GRKP 551 L ++APE G YT SDV+SFG++M E+++ G +P Sbjct: 818 LRWAAPEVITHGKYTTSSDVWSFGILMWEVMSYGERP 854
>RAF1_CHICK (P05625) RAF proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (RAF-1) (C-RAF) (MIL proto-oncogene serine/threonine-protein kinase) (C-MIL) Length = 647 Score = 38.1 bits (87), Expect = 0.024 Identities = 32/128 (25%), Positives = 56/128 (43%), Gaps = 3/128 (2%) Frame = -3 Query: 628 SGTYTVKSDVYSFGVVMLELLTGRKPLDRSRERSEQSLV---GWATPQLHDIDALAKMVD 458 S ++ +SDVYS+G+V+ EL+TG P R + + G+A+P D+ L K Sbjct: 522 SNPFSFQSDVYSYGIVLYELMTGELPYSHINNRDQIIFMVGRGYASP---DLSKLYKNCP 578 Query: 457 PAMDGMYPAKSLSRFADIIALSVQPEPEFRPPISEVVQQLVRLMQRASMLRRQSGDDLGS 278 AM ++A ++ E RP +++ + L + R + + S Sbjct: 579 KAM------------KRLVADCLKKVREERPLFPQILSSIELLQHSLPKINRSASEP--S 624 Query: 277 SYRAPERE 254 +RA E Sbjct: 625 LHRASHTE 632
>EPHB6_RAT (P0C0K7) Ephrin type-B receptor 6 precursor (Tyrosine-protein| kinase-defective receptor EPH-6) Length = 1013 Score = 38.1 bits (87), Expect = 0.024 Identities = 17/37 (45%), Positives = 26/37 (70%), Gaps = 1/37 (2%) Frame = -3 Query: 658 LEYSAPEFAMSGTYTVKSDVYSFGVVMLELLT-GRKP 551 L ++APE G YT SDV+SFG++M E+++ G +P Sbjct: 817 LRWAAPEVITHGKYTTSSDVWSFGILMWEVMSYGERP 853
>MP2K6_MOUSE (P70236) Dual specificity mitogen-activated protein kinase kinase 6| (EC 2.7.12.2) (MAP kinase kinase 6) (MAPKK 6) (MAPK/ERK kinase 6) (SAPKK3) Length = 334 Score = 38.1 bits (87), Expect = 0.024 Identities = 28/100 (28%), Positives = 44/100 (44%) Frame = -3 Query: 643 PEFAMSGTYTVKSDVYSFGVVMLELLTGRKPLDRSRERSEQSLVGWATPQLHDIDALAKM 464 PE G Y+VKSD++S G+ M+EL R P D W TP L ++ Sbjct: 227 PELNQKG-YSVKSDIWSLGITMIELAILRFPYD-----------SWGTP----FQQLKQV 270 Query: 463 VDPAMDGMYPAKSLSRFADIIALSVQPEPEFRPPISEVVQ 344 V+ + K + F D + ++ + RP E++Q Sbjct: 271 VEEPSPQLPADKFSADFVDFTSQCLKKNSKERPTYPELMQ 310
>M3K7_MOUSE (Q62073) Mitogen-activated protein kinase kinase kinase 7 (EC| 2.7.11.25) (Transforming growth factor-beta-activated kinase 1) (TGF-beta-activated kinase 1) Length = 579 Score = 37.7 bits (86), Expect = 0.031 Identities = 15/36 (41%), Positives = 24/36 (66%) Frame = -3 Query: 652 YSAPEFAMSGTYTVKSDVYSFGVVMLELLTGRKPLD 545 + APE Y+ K DV+S+G+++ E++T RKP D Sbjct: 195 WMAPEVFEGSNYSEKCDVFSWGIILWEVITRRKPFD 230
>KS6A3_MOUSE (P18654) Ribosomal protein S6 kinase alpha-3 (EC 2.7.11.1)| (S6K-alpha 3) (90 kDa ribosomal protein S6 kinase 3) (p90-RSK 3) (Ribosomal S6 kinase 2) (RSK-2) (pp90RSK2) (MAP kinase-activated protein kinase 1b) (MAPKAPK1B) Length = 740 Score = 37.7 bits (86), Expect = 0.031 Identities = 19/45 (42%), Positives = 28/45 (62%) Frame = -3 Query: 658 LEYSAPEFAMSGTYTVKSDVYSFGVVMLELLTGRKPLDRSRERSE 524 +EY APE +T +D +SFGV+M E+LTG P + ++R E Sbjct: 232 VEYMAPEVVNRRGHTQSADWWSFGVLMFEMLTGTLPF-QGKDRKE 275
>KS6A3_HUMAN (P51812) Ribosomal protein S6 kinase alpha-3 (EC 2.7.11.1)| (S6K-alpha 3) (90 kDa ribosomal protein S6 kinase 3) (p90-RSK 3) (Ribosomal S6 kinase 2) (RSK-2) (pp90RSK2) (Insulin-stimulated protein kinase 1) (ISPK-1) (MAP kinase-activated protei Length = 740 Score = 37.7 bits (86), Expect = 0.031 Identities = 19/45 (42%), Positives = 28/45 (62%) Frame = -3 Query: 658 LEYSAPEFAMSGTYTVKSDVYSFGVVMLELLTGRKPLDRSRERSE 524 +EY APE +T +D +SFGV+M E+LTG P + ++R E Sbjct: 232 VEYMAPEVVNRRGHTQSADWWSFGVLMFEMLTGTLPF-QGKDRKE 275
>SRC42_DROME (Q9V9J3) Tyrosine-protein kinase Src42A (EC 2.7.10.2) (Dsrc41)| Length = 517 Score = 37.7 bits (86), Expect = 0.031 Identities = 17/37 (45%), Positives = 29/37 (78%), Gaps = 1/37 (2%) Frame = -3 Query: 658 LEYSAPEFAMSGTYTVKSDVYSFGVVMLELLT-GRKP 551 ++++APE A +++KSDV+SFG+++ EL+T GR P Sbjct: 410 IKWTAPEAANYSKFSIKSDVWSFGILLTELVTYGRIP 446
>M3K7_HUMAN (O43318) Mitogen-activated protein kinase kinase kinase 7 (EC| 2.7.11.25) (Transforming growth factor-beta-activated kinase 1) (TGF-beta-activated kinase 1) Length = 606 Score = 37.7 bits (86), Expect = 0.031 Identities = 15/36 (41%), Positives = 24/36 (66%) Frame = -3 Query: 652 YSAPEFAMSGTYTVKSDVYSFGVVMLELLTGRKPLD 545 + APE Y+ K DV+S+G+++ E++T RKP D Sbjct: 195 WMAPEVFEGSNYSEKCDVFSWGIILWEVITRRKPFD 230
>LYN_RAT (Q07014) Tyrosine-protein kinase Lyn (EC 2.7.10.2)| Length = 511 Score = 37.7 bits (86), Expect = 0.031 Identities = 14/32 (43%), Positives = 26/32 (81%) Frame = -3 Query: 658 LEYSAPEFAMSGTYTVKSDVYSFGVVMLELLT 563 ++++APE G +T+KSDV+SFG+++ E++T Sbjct: 406 IKWTAPEAINFGCFTIKSDVWSFGILLYEIVT 437
>LYN_MOUSE (P25911) Tyrosine-protein kinase Lyn (EC 2.7.10.2)| Length = 511 Score = 37.7 bits (86), Expect = 0.031 Identities = 14/32 (43%), Positives = 26/32 (81%) Frame = -3 Query: 658 LEYSAPEFAMSGTYTVKSDVYSFGVVMLELLT 563 ++++APE G +T+KSDV+SFG+++ E++T Sbjct: 406 IKWTAPEAINFGCFTIKSDVWSFGILLYEIVT 437
>LYN_HUMAN (P07948) Tyrosine-protein kinase Lyn (EC 2.7.10.2)| Length = 511 Score = 37.7 bits (86), Expect = 0.031 Identities = 14/32 (43%), Positives = 26/32 (81%) Frame = -3 Query: 658 LEYSAPEFAMSGTYTVKSDVYSFGVVMLELLT 563 ++++APE G +T+KSDV+SFG+++ E++T Sbjct: 406 IKWTAPEAINFGCFTIKSDVWSFGILLYEIVT 437
>BYR1_SCHPO (P10506) Protein kinase byr1 (EC 2.7.12.2) (MAPK kinase) (MAPKK)| Length = 340 Score = 37.4 bits (85), Expect = 0.041 Identities = 16/34 (47%), Positives = 22/34 (64%) Frame = -3 Query: 652 YSAPEFAMSGTYTVKSDVYSFGVVMLELLTGRKP 551 Y +PE G YTVKSD++S G+ ++EL T P Sbjct: 225 YMSPERIRGGKYTVKSDIWSLGISIIELATQELP 258
>CTR1_ARATH (Q05609) Serine/threonine-protein kinase CTR1 (EC 2.7.11.1)| Length = 821 Score = 37.4 bits (85), Expect = 0.041 Identities = 28/89 (31%), Positives = 41/89 (46%), Gaps = 2/89 (2%) Frame = -3 Query: 655 EYSAPEFAMSGTYTVKSDVYSFGVVMLELLTGRKPLDRSRERSEQSLVGWATPQLHDIDA 476 E+ APE KSDVYSFGV++ EL T ++P + VG+ +L Sbjct: 716 EWMAPEVLRDEPSNEKSDVYSFGVILWELATLQQPWGNLNPAQVVAAVGFKCKRLEIPRN 775 Query: 475 LAKMVDPAMDGMYPAKSLSR--FADIIAL 395 L V ++G + + R FA I+ L Sbjct: 776 LNPQVAAIIEGCWTNEPWKRPSFATIMDL 804
>VGFR2_HUMAN (P35968) Vascular endothelial growth factor receptor 2 precursor (EC| 2.7.10.1) (VEGFR-2) (Kinase insert domain receptor) (Protein-tyrosine kinase receptor Flk-1) (CD309 antigen) Length = 1356 Score = 37.4 bits (85), Expect = 0.041 Identities = 35/135 (25%), Positives = 56/135 (41%), Gaps = 11/135 (8%) Frame = -3 Query: 658 LEYSAPEFAMSGTYTVKSDVYSFGVVMLELLT-GRKPLD----------RSRERSEQSLV 512 L++ APE YT++SDV+SFGV++ E+ + G P R +E + Sbjct: 1069 LKWMAPETIFDRVYTIQSDVWSFGVLLWEIFSLGASPYPGVKIDEEFCRRLKEGTRMRAP 1128 Query: 511 GWATPQLHDIDALAKMVDPAMDGMYPAKSLSRFADIIALSVQPEPEFRPPISEVVQQLVR 332 + TP+++ M+D EP RP SE+V+ L Sbjct: 1129 DYTTPEMYQ-----TMLD---------------------CWHGEPSQRPTFSELVEHLGN 1162 Query: 331 LMQRASMLRRQSGDD 287 L+Q + +Q G D Sbjct: 1163 LLQANA---QQDGKD 1174
>KGP25_DROME (P32023) cGMP-dependent protein kinase, isozyme 2 forms cD5/T2 (EC| 2.7.11.12) (CGK) (Foraging protein) Length = 934 Score = 37.4 bits (85), Expect = 0.041 Identities = 17/39 (43%), Positives = 24/39 (61%) Frame = -3 Query: 655 EYSAPEFAMSGTYTVKSDVYSFGVVMLELLTGRKPLDRS 539 EY APE ++ + + +D +S GV+M ELLTG P S Sbjct: 786 EYVAPEVILNRGHDISADYWSLGVLMFELLTGTPPFTGS 824
>KGP24_DROME (Q03043) cGMP-dependent protein kinase, isozyme 2 forms| cD4/T1/T3A/T3B (EC 2.7.11.12) (CGK) (Foraging protein) Length = 1088 Score = 37.4 bits (85), Expect = 0.041 Identities = 17/39 (43%), Positives = 24/39 (61%) Frame = -3 Query: 655 EYSAPEFAMSGTYTVKSDVYSFGVVMLELLTGRKPLDRS 539 EY APE ++ + + +D +S GV+M ELLTG P S Sbjct: 940 EYVAPEVILNRGHDISADYWSLGVLMFELLTGTPPFTGS 978
>KCCS_MALDO (Q07250) Calcium/calmodulin-dependent serine/threonine-protein| kinase (EC 2.7.11.17) Length = 415 Score = 37.4 bits (85), Expect = 0.041 Identities = 16/49 (32%), Positives = 28/49 (57%) Frame = -3 Query: 658 LEYSAPEFAMSGTYTVKSDVYSFGVVMLELLTGRKPLDRSRERSEQSLV 512 ++Y +PE G T KSD+++ GV++ LL+G P R +Q ++ Sbjct: 214 IDYVSPEALSQGQVTSKSDMWALGVILYILLSGYPPFIAQSNRQKQQMI 262
>TOPK_BRARE (Q6DHU8) T-lymphokine-activated killer cell-originated protein| kinase homolog (EC 2.7.12.2) (PDZ-binding kinase) Length = 339 Score = 37.4 bits (85), Expect = 0.041 Identities = 24/99 (24%), Positives = 49/99 (49%), Gaps = 3/99 (3%) Frame = -3 Query: 625 GTYTVKSDVYSFGVVMLELLTGRKP-LDRSRERSEQSLVGWATPQLHDIDALAKMVD--P 455 G T K+D++++G+ + E++T P L+ ++ + + D DA + + P Sbjct: 224 GVITDKADIFAYGLTLWEMMTLSVPHLEMLDTEGDEDDDDESFEEDFDEDAYYERLGSRP 283 Query: 454 AMDGMYPAKSLSRFADIIALSVQPEPEFRPPISEVVQQL 338 A+D + S R ++ L + +P+ RP + +VQ L Sbjct: 284 ALDAVTLGGSYQRMVELFCLCTEEDPQKRPSAAHIVQVL 322
>BLK_MOUSE (P16277) Tyrosine-protein kinase BLK (EC 2.7.10.2) (B lymphocyte| kinase) (p55-BLK) Length = 498 Score = 37.4 bits (85), Expect = 0.041 Identities = 16/37 (43%), Positives = 29/37 (78%), Gaps = 1/37 (2%) Frame = -3 Query: 658 LEYSAPEFAMSGTYTVKSDVYSFGVVMLELLT-GRKP 551 ++++APE G +T+K+DV+SFGV+++ ++T GR P Sbjct: 392 IKWTAPEAIHFGVFTIKADVWSFGVLLMVIVTYGRVP 428
>PKN3_MYXXA (Q9XBQ0) Serine/threonine-protein kinase pkn3 (EC 2.7.11.1)| Length = 547 Score = 37.4 bits (85), Expect = 0.041 Identities = 20/55 (36%), Positives = 30/55 (54%) Frame = -3 Query: 655 EYSAPEFAMSGTYTVKSDVYSFGVVMLELLTGRKPLDRSRERSEQSLVGWATPQL 491 EY +PE A +SD+Y+ GV++ +L+TG P + S VG+AT L Sbjct: 191 EYMSPEQARGSQLDHRSDLYAVGVILYQLMTGLLPFE------SDSAVGFATKHL 239
>POLO_DROME (P52304) Serine/threonine-protein kinase polo (EC 2.7.11.21)| Length = 576 Score = 37.4 bits (85), Expect = 0.041 Identities = 27/102 (26%), Positives = 44/102 (43%) Frame = -3 Query: 652 YSAPEFAMSGTYTVKSDVYSFGVVMLELLTGRKPLDRSRERSEQSLVGWATPQLHDIDAL 473 Y APE ++ + D++S G VM LL G+ P + T L D + Sbjct: 189 YIAPEILTKKGHSFEVDIWSIGCVMYTLLVGQPPFE--------------TKTLKDTYSK 234 Query: 472 AKMVDPAMDGMYPAKSLSRFADIIALSVQPEPEFRPPISEVV 347 K + + P+ AD++ +QP PE RP I +++ Sbjct: 235 IKKCEYRV----PSYLRKPAADMVIAMLQPNPESRPAIGQLL 272
>FRK_HUMAN (P42685) Tyrosine-protein kinase FRK (EC 2.7.10.2) (Nuclear| tyrosine protein kinase RAK) Length = 505 Score = 37.4 bits (85), Expect = 0.041 Identities = 15/37 (40%), Positives = 29/37 (78%), Gaps = 1/37 (2%) Frame = -3 Query: 658 LEYSAPEFAMSGTYTVKSDVYSFGVVMLELLT-GRKP 551 ++++APE S +++KSDV+SFG+++ E++T G+ P Sbjct: 397 VKWTAPEAIRSNKFSIKSDVWSFGILLYEIITYGKMP 433
>PDK1L_PONPY (Q5RER6) Serine/threonine-protein kinase PDIK1L (EC 2.7.11.1)| (PDLIM1-interacting kinase 1-like) Length = 340 Score = 37.0 bits (84), Expect = 0.053 Identities = 30/113 (26%), Positives = 56/113 (49%), Gaps = 5/113 (4%) Frame = -3 Query: 652 YSAPEFAMSGTYTVKSDVYSFGVVMLELLTGRKPLDRSRERSEQSLVGWATPQLHDIDAL 473 Y APE G YT K+D+++ G+++ +L +D +++ L+G Q +I + Sbjct: 223 YMAPE-VWEGHYTAKADIFALGIIIWAMLERITFID---TETKKELLGSYVKQGTEIVPV 278 Query: 472 --AKMVDPAMDGMYPAKSLS---RFADIIALSVQPEPEFRPPISEVVQQLVRL 329 A + +P M+ + P K S R +I + P+ RP E+ +LV++ Sbjct: 279 GEALLENPKMELLIPVKKKSMNGRMKQLIKEMLAANPQDRPDAFELELRLVQI 331
>GSK31_SCHPO (Q9URT9) Protein kinase gsk31 (EC 2.7.11.1)| Length = 381 Score = 37.0 bits (84), Expect = 0.053 Identities = 24/63 (38%), Positives = 31/63 (49%), Gaps = 3/63 (4%) Frame = -3 Query: 652 YSAPEFAMSGT-YTVKSDVYSFGVVMLELLTGRK--PLDRSRERSEQSLVGWATPQLHDI 482 Y APE T YT K DV+S V+ EL GR P D S E+ + + TP H+I Sbjct: 191 YRAPELVFGATHYTTKIDVWSAACVIAELFIGRPLFPGDSSVEQLVEIIRVLGTPSYHEI 250 Query: 481 DAL 473 + Sbjct: 251 SVM 253
>BRAF1_HUMAN (P15056) B-Raf proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (p94) (v-Raf murine sarcoma viral oncogene homolog B1) Length = 766 Score = 37.0 bits (84), Expect = 0.053 Identities = 17/49 (34%), Positives = 29/49 (59%), Gaps = 3/49 (6%) Frame = -3 Query: 619 YTVKSDVYSFGVVMLELLTGRKPLDRSRERSEQSLV---GWATPQLHDI 482 Y+ +SDVY+FG+V+ EL+TG+ P R + + G+ +P L + Sbjct: 633 YSFQSDVYAFGIVLYELMTGQLPYSNINNRDQIIFMVGRGYLSPDLSKV 681
>EPHA2_HUMAN (P29317) Ephrin type-A receptor 2 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor ECK) (Epithelial cell kinase) Length = 976 Score = 37.0 bits (84), Expect = 0.053 Identities = 34/137 (24%), Positives = 57/137 (41%), Gaps = 1/137 (0%) Frame = -3 Query: 658 LEYSAPEFAMSGTYTVKSDVYSFGVVMLELLT-GRKPLDRSRERSEQSLVGWATPQLHDI 482 + ++APE +T SDV+SFG+VM E++T G +P W H++ Sbjct: 781 IRWTAPEAISYRKFTSASDVWSFGIVMWEVMTYGERPY-------------WELSN-HEV 826 Query: 481 DALAKMVDPAMDGMYPAKSLSRFADIIALSVQPEPEFRPPISEVVQQLVRLMQRASMLRR 302 K ++ P S ++ Q E RP +++V L +L++ L+ Sbjct: 827 ---MKAINDGFRLPTPMDCPSAIYQLMMQCWQQERARRPKFADIVSILDKLIRAPDSLKT 883 Query: 301 QSGDDLGSSYRAPEREG 251 + D S R P G Sbjct: 884 LADFDPRVSIRLPSTSG 900
>PKN5_MYXXA (P54737) Serine/threonine-protein kinase pkn5 (EC 2.7.11.1)| Length = 380 Score = 37.0 bits (84), Expect = 0.053 Identities = 16/36 (44%), Positives = 23/36 (63%) Frame = -3 Query: 652 YSAPEFAMSGTYTVKSDVYSFGVVMLELLTGRKPLD 545 Y APE + ++D+YS GV++ ELL+GR P D Sbjct: 287 YMAPEQILGEPLDGRADLYSLGVILYELLSGRPPFD 322
>LRRK1_HUMAN (Q38SD2) Leucine-rich repeat serine/threonine-protein kinase 1 (EC| 2.7.11.1) Length = 2038 Score = 37.0 bits (84), Expect = 0.053 Identities = 29/105 (27%), Positives = 44/105 (41%) Frame = -3 Query: 652 YSAPEFAMSGTYTVKSDVYSFGVVMLELLTGRKPLDRSRERSEQSLVGWATPQLHDIDAL 473 Y APE Y K D++S+G+V+ ELL+G++P QL L Sbjct: 1453 YQAPEIRPRIVYDEKVDMFSYGMVLYELLSGQRP-------------ALGHHQLQIAKKL 1499 Query: 472 AKMVDPAMDGMYPAKSLSRFADIIALSVQPEPEFRPPISEVVQQL 338 +K + P + G R ++ +PE RP VV Q+ Sbjct: 1500 SKGIRPVL-GQPEEVQFRRLQALMMECWDTKPEKRPLALSVVSQM 1543
>KS6A1_RAT (Q63531) Ribosomal protein S6 kinase alpha-1 (EC 2.7.11.1)| (S6K-alpha 1) (90 kDa ribosomal protein S6 kinase 1) (p90-RSK 1) (Ribosomal S6 kinase 1) (RSK-1) (pp90RSK1) (MAP kinase-activated protein kinase 1a) (MAPKAPK1A) Length = 735 Score = 37.0 bits (84), Expect = 0.053 Identities = 17/49 (34%), Positives = 27/49 (55%) Frame = -3 Query: 658 LEYSAPEFAMSGTYTVKSDVYSFGVVMLELLTGRKPLDRSRERSEQSLV 512 +EY APE +T +D +S+GV+M E+LTG P + +L+ Sbjct: 226 VEYMAPEVVNRQGHTHSADWWSYGVLMFEMLTGSLPFQGKDRKETMTLI 274
>RMIL_AVII1 (P10533) Serine/threonine-protein kinase transforming protein Rmil| (EC 2.7.11.1) Length = 367 Score = 37.0 bits (84), Expect = 0.053 Identities = 17/49 (34%), Positives = 29/49 (59%), Gaps = 3/49 (6%) Frame = -3 Query: 619 YTVKSDVYSFGVVMLELLTGRKPLDRSRERSEQSLV---GWATPQLHDI 482 Y+ +SDVY+FG+V+ EL+TG+ P R + + G+ +P L + Sbjct: 243 YSFQSDVYAFGIVLYELMTGQLPYSNINNRDQIIFMVGRGYLSPDLSKV 291
>BRAF1_MOUSE (P28028) B-Raf proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (Fragment) Length = 328 Score = 37.0 bits (84), Expect = 0.053 Identities = 17/49 (34%), Positives = 29/49 (59%), Gaps = 3/49 (6%) Frame = -3 Query: 619 YTVKSDVYSFGVVMLELLTGRKPLDRSRERSEQSLV---GWATPQLHDI 482 Y+ +SDVY+FG+V+ EL+TG+ P R + + G+ +P L + Sbjct: 195 YSFQSDVYAFGIVLYELMTGQLPYSNINNRDQIIFMVGRGYLSPDLSKV 243
>PKN2_CORGL (Q8NU97) Serine/threonine protein kinases pknA (EC 2.7.11.1)| Length = 469 Score = 37.0 bits (84), Expect = 0.053 Identities = 16/35 (45%), Positives = 22/35 (62%) Frame = -3 Query: 655 EYSAPEFAMSGTYTVKSDVYSFGVVMLELLTGRKP 551 +Y +PE A T SD+YS GVV E++ GR+P Sbjct: 189 QYVSPEQAQGKEVTAASDIYSLGVVGYEMMAGRRP 223
>BRAF1_CHICK (Q04982) B-Raf proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (Rmil serine/threonine-protein kinase) (c-Rmil) Length = 806 Score = 37.0 bits (84), Expect = 0.053 Identities = 17/49 (34%), Positives = 29/49 (59%), Gaps = 3/49 (6%) Frame = -3 Query: 619 YTVKSDVYSFGVVMLELLTGRKPLDRSRERSEQSLV---GWATPQLHDI 482 Y+ +SDVY+FG+V+ EL+TG+ P R + + G+ +P L + Sbjct: 673 YSFQSDVYAFGIVLYELMTGQLPYSNINNRDQIIFMVGRGYLSPDLSKV 721
>BRAF1_COTJA (P34908) B-Raf proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (RMIL serine/threonine-protein kinase) (c-RMIL) Length = 807 Score = 37.0 bits (84), Expect = 0.053 Identities = 17/49 (34%), Positives = 29/49 (59%), Gaps = 3/49 (6%) Frame = -3 Query: 619 YTVKSDVYSFGVVMLELLTGRKPLDRSRERSEQSLV---GWATPQLHDI 482 Y+ +SDVY+FG+V+ EL+TG+ P R + + G+ +P L + Sbjct: 673 YSFQSDVYAFGIVLYELMTGQLPYSNINNRDQIIFMVGRGYLSPDLSKV 721
>STK25_HUMAN (O00506) Serine/threonine-protein kinase 25 (EC 2.7.11.1) (Sterile| 20/oxidant stress-response kinase 1) (Ste20/oxidant stress response kinase 1) (SOK-1) (Ste20-like kinase) Length = 426 Score = 37.0 bits (84), Expect = 0.053 Identities = 27/120 (22%), Positives = 47/120 (39%), Gaps = 5/120 (4%) Frame = -3 Query: 652 YSAPEFAMSGTYTVKSDVYSFGVVMLELLTGRKPLDRSRERSEQSLVGWATPQLHDIDAL 473 + APE Y K+D++S G+ +EL G P LH + L Sbjct: 181 WMAPEVIKQSAYDFKADIWSLGITAIELAKGEPP----------------NSDLHPMRVL 224 Query: 472 ---AKMVDPAMDGMYPAKSLSRFADIIALSVQPEPEFRPPISEVVQQ--LVRLMQRASML 308 K P ++G + F + + + +P FRP E+++ + R ++ S L Sbjct: 225 FLIPKNSPPTLEGQHS----KPFKEFVEACLNKDPRFRPTAKELLKHKFITRYTKKTSFL 280
>VGFR2_COTJA (P52583) Vascular endothelial growth factor receptor 2 precursor (EC| 2.7.10.1) (VEGFR-2) (Endothelial kinase receptor EK1) (Quek 1) (Quek1) Length = 1348 Score = 37.0 bits (84), Expect = 0.053 Identities = 35/135 (25%), Positives = 56/135 (41%), Gaps = 11/135 (8%) Frame = -3 Query: 658 LEYSAPEFAMSGTYTVKSDVYSFGVVMLELLT-GRKPLD----------RSRERSEQSLV 512 L++ APE YT++SDV+SFGV++ E+ + G P R +E + Sbjct: 1062 LKWMAPETIFDRVYTIQSDVWSFGVLLWEIFSLGASPYPGVKIDEEFCRRLKEGTRMRAP 1121 Query: 511 GWATPQLHDIDALAKMVDPAMDGMYPAKSLSRFADIIALSVQPEPEFRPPISEVVQQLVR 332 + TP+++ M+D +P+ RP SE+V+ L Sbjct: 1122 DYTTPEMYQ-----TMLD---------------------CWHGDPKQRPTFSELVEHLGN 1155 Query: 331 LMQRASMLRRQSGDD 287 L+Q RQ G D Sbjct: 1156 LLQANV---RQDGKD 1167
>RMIL_AVEVR (P27966) Serine/threonine-protein kinase transforming protein Rmil| (EC 2.7.11.1) Length = 450 Score = 37.0 bits (84), Expect = 0.053 Identities = 17/49 (34%), Positives = 29/49 (59%), Gaps = 3/49 (6%) Frame = -3 Query: 619 YTVKSDVYSFGVVMLELLTGRKPLDRSRERSEQSLV---GWATPQLHDI 482 Y+ +SDVY+FG+V+ EL+TG+ P R + + G+ +P L + Sbjct: 259 YSFQSDVYAFGIVLYELMTGQLPYSNINNRDQIIFMVGRGYLSPDLSKV 307
>PDK1L_MOUSE (Q8QZR7) Serine/threonine-protein kinase PDIK1L (EC 2.7.11.1)| (PDLIM1-interacting kinase 1-like) Length = 341 Score = 37.0 bits (84), Expect = 0.053 Identities = 30/113 (26%), Positives = 56/113 (49%), Gaps = 5/113 (4%) Frame = -3 Query: 652 YSAPEFAMSGTYTVKSDVYSFGVVMLELLTGRKPLDRSRERSEQSLVGWATPQLHDIDAL 473 Y APE G YT K+D+++ G+++ +L +D +++ L+G Q +I + Sbjct: 224 YMAPE-VWEGHYTAKADIFALGIIIWAMLERITFID---TETKKELLGSYVKQGTEIVPV 279 Query: 472 --AKMVDPAMDGMYPAKSLS---RFADIIALSVQPEPEFRPPISEVVQQLVRL 329 A + +P M+ + P K S R +I + P+ RP E+ +LV++ Sbjct: 280 GEALLENPKMELLIPVKKKSMNGRMKQLIKEMLAANPQDRPDAFELELRLVQI 332
>PDK1L_HUMAN (Q8N165) Serine/threonine-protein kinase PDIK1L (EC 2.7.11.1)| (PDLIM1-interacting kinase 1-like) Length = 341 Score = 37.0 bits (84), Expect = 0.053 Identities = 30/113 (26%), Positives = 56/113 (49%), Gaps = 5/113 (4%) Frame = -3 Query: 652 YSAPEFAMSGTYTVKSDVYSFGVVMLELLTGRKPLDRSRERSEQSLVGWATPQLHDIDAL 473 Y APE G YT K+D+++ G+++ +L +D +++ L+G Q +I + Sbjct: 224 YMAPE-VWEGHYTAKADIFALGIIIWAMLERITFID---TETKKELLGSYVKQGTEIVPV 279 Query: 472 --AKMVDPAMDGMYPAKSLS---RFADIIALSVQPEPEFRPPISEVVQQLVRL 329 A + +P M+ + P K S R +I + P+ RP E+ +LV++ Sbjct: 280 GEALLENPKMELLIPVKKKSMNGRMKQLIKEMLAANPQDRPDAFELELRLVQI 332
>M3K8_HUMAN (P41279) Mitogen-activated protein kinase kinase kinase 8 (EC| 2.7.11.25) (COT proto-oncogene serine/threonine-protein kinase) (C-COT) (Cancer Osaka thyroid oncogene) Length = 467 Score = 37.0 bits (84), Expect = 0.053 Identities = 31/125 (24%), Positives = 51/125 (40%), Gaps = 4/125 (3%) Frame = -3 Query: 652 YSAPEFAMSGTYTVKSDVYSFGVVMLELLTGRKP----LDRSRERSEQSLVGWATPQLHD 485 Y +PE + ++ K+D+YS G ++ + TG P RS S ++ P L D Sbjct: 293 YMSPEVILCRGHSTKADIYSLGATLIHMQTGTPPWVKRYPRSAYPSYLYIIHKQAPPLED 352 Query: 484 IDALAKMVDPAMDGMYPAKSLSRFADIIALSVQPEPEFRPPISEVVQQLVRLMQRASMLR 305 I D GM ++I S++ P RP +++++ R R Sbjct: 353 I------ADDCSPGM---------RELIEASLERNPNHRPRAADLLKHEALNPPREDQPR 397 Query: 304 RQSGD 290 QS D Sbjct: 398 CQSLD 402
>ITK_HUMAN (Q08881) Tyrosine-protein kinase ITK/TSK (EC 2.7.10.2)| (T-cell-specific kinase) (Tyrosine-protein kinase Lyk) (Kinase EMT) Length = 620 Score = 36.6 bits (83), Expect = 0.070 Identities = 28/112 (25%), Positives = 52/112 (46%) Frame = -3 Query: 658 LEYSAPEFAMSGTYTVKSDVYSFGVVMLELLTGRKPLDRSRERSEQSLVGWATPQLHDID 479 +++++PE Y+ KSDV+SFGV+M E+ + K +R SE + DI Sbjct: 522 VKWASPEVFSFSRYSSKSDVWSFGVLMWEVFSEGKIPYENRSNSE---------VVEDIS 572 Query: 478 ALAKMVDPAMDGMYPAKSLSRFADIIALSVQPEPEFRPPISEVVQQLVRLMQ 323 ++ P + + + I+ + PE RP S +++QL + + Sbjct: 573 TGFRLYKPRL-------ASTHVYQIMNHCWKERPEDRPAFSRLLRQLAEIAE 617
>DYRK3_HUMAN (O43781) Dual specificity tyrosine-phosphorylation-regulated kinase| 3 (EC 2.7.12.1) Length = 588 Score = 36.6 bits (83), Expect = 0.070 Identities = 22/67 (32%), Positives = 34/67 (50%), Gaps = 5/67 (7%) Frame = -3 Query: 652 YSAPEFAMSGTYTVKSDVYSFGVVMLELLTGRKPLDRSRERSEQ-----SLVGWATPQLH 488 Y APE + Y+ D++SF ++ ELLTG +PL + +Q L+G P+L Sbjct: 375 YRAPEIILGSRYSTPIDIWSFRCILAELLTG-QPLFPGEDEGDQLACMMELLGMPPPKLL 433 Query: 487 DIDALAK 467 + AK Sbjct: 434 EQSKRAK 440
>VGFR2_MOUSE (P35918) Vascular endothelial growth factor receptor 2 precursor (EC| 2.7.10.1) (VEGFR-2) (Protein-tyrosine kinase receptor flk-1) (Fetal liver kinase 1) (Kinase NYK) Length = 1367 Score = 36.6 bits (83), Expect = 0.070 Identities = 34/135 (25%), Positives = 56/135 (41%), Gaps = 11/135 (8%) Frame = -3 Query: 658 LEYSAPEFAMSGTYTVKSDVYSFGVVMLELLT-GRKPLD----------RSRERSEQSLV 512 L++ APE YT++SDV+SFGV++ E+ + G P R +E + Sbjct: 1067 LKWMAPETIFDRVYTIQSDVWSFGVLLWEIFSLGASPYPGVKIDEEFCRRLKEGTRMRAP 1126 Query: 511 GWATPQLHDIDALAKMVDPAMDGMYPAKSLSRFADIIALSVQPEPEFRPPISEVVQQLVR 332 + TP+++ M+D +P RP SE+V+ L Sbjct: 1127 DYTTPEMYQ-----TMLD---------------------CWHEDPNQRPSFSELVEHLGN 1160 Query: 331 LMQRASMLRRQSGDD 287 L+Q + +Q G D Sbjct: 1161 LLQANA---QQDGKD 1172
>ULK1_MOUSE (O70405) Serine/threonine-protein kinase ULK1 (EC 2.7.11.1)| (Unc-51-like kinase 1) (Serine/threonine-protein kinase Unc51.1) Length = 1051 Score = 36.6 bits (83), Expect = 0.070 Identities = 16/38 (42%), Positives = 23/38 (60%) Frame = -3 Query: 652 YSAPEFAMSGTYTVKSDVYSFGVVMLELLTGRKPLDRS 539 Y APE MS Y K+D++S G ++ + LTG+ P S Sbjct: 187 YMAPEVIMSQHYDGKADLWSIGTIVYQCLTGKAPFQAS 224
>ULK1_HUMAN (O75385) Serine/threonine-protein kinase ULK1 (EC 2.7.11.1)| (Unc-51-like kinase 1) Length = 1050 Score = 36.6 bits (83), Expect = 0.070 Identities = 16/38 (42%), Positives = 23/38 (60%) Frame = -3 Query: 652 YSAPEFAMSGTYTVKSDVYSFGVVMLELLTGRKPLDRS 539 Y APE MS Y K+D++S G ++ + LTG+ P S Sbjct: 187 YMAPEVIMSQHYDGKADLWSIGTIVYQCLTGKAPFQAS 224
>PTK7_CHICK (Q91048) Tyrosine-protein kinase-like 7 precursor (Kinase-like| protein) Length = 1051 Score = 36.6 bits (83), Expect = 0.070 Identities = 30/108 (27%), Positives = 43/108 (39%), Gaps = 1/108 (0%) Frame = -3 Query: 658 LEYSAPEFAMSGTYTVKSDVYSFGVVMLELLT-GRKPLDRSRERSEQSLVGWATPQLHDI 482 L + PE + ++ KSDV+SFGV+M E+ T G P L D Sbjct: 951 LRWMPPEAVLEDEFSTKSDVWSFGVLMWEVFTQGEMPY----------------APLADD 994 Query: 481 DALAKMVDPAMDGMYPAKSLSRFADIIALSVQPEPEFRPPISEVVQQL 338 + LA + P SR ++ P P+ RP SE+ L Sbjct: 995 EVLAGLKSGKTKLPQPEGCPSRLTKLMQRCWAPSPKDRPSFSELAAAL 1042
>IRAK1_HUMAN (P51617) Interleukin-1 receptor-associated kinase 1 (EC 2.7.11.1)| (IRAK-1) Length = 712 Score = 36.6 bits (83), Expect = 0.070 Identities = 34/137 (24%), Positives = 55/137 (40%), Gaps = 27/137 (19%) Frame = -3 Query: 658 LEYSAPEFAMSGTYTVKSDVYSFGVVMLELLTGRKPL-----------DRSRERSEQSLV 512 L Y E+ +G V +D +SFGVV+LE L G++ + D E +E++ V Sbjct: 388 LAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGV 447 Query: 511 ----------------GWATPQLHDIDALAKMVDPAMDGMYPAKSLSRFADIIALSVQPE 380 WA P I K +DP P L + + Sbjct: 448 ALRSTQSTLQAGLAADAWAAPIAMQI--YKKHLDPRPGPCPPELGLG-LGQLACCCLHRR 504 Query: 379 PEFRPPISEVVQQLVRL 329 + RPP+++V ++L +L Sbjct: 505 AKRRPPMTQVYERLEKL 521
>PKNB_MYCLE (P54744) Probable serine/threonine-protein kinase pknB (EC| 2.7.11.1) Length = 622 Score = 36.6 bits (83), Expect = 0.070 Identities = 16/35 (45%), Positives = 22/35 (62%) Frame = -3 Query: 655 EYSAPEFAMSGTYTVKSDVYSFGVVMLELLTGRKP 551 +Y +PE A + +SDVYS G V+ E+LTG P Sbjct: 180 QYLSPEQARGDSVDARSDVYSLGCVLYEILTGEPP 214
>CHK1_CAEBR (Q61RA2) Serine/threonine-protein kinase chk-1 (EC 2.7.11.1)| Length = 493 Score = 36.6 bits (83), Expect = 0.070 Identities = 18/45 (40%), Positives = 27/45 (60%), Gaps = 1/45 (2%) Frame = -3 Query: 658 LEYSAPEFAMSGTYTVKS-DVYSFGVVMLELLTGRKPLDRSRERS 527 + Y+APE G Y DV+S G+V++ +LTG P DR+ + S Sbjct: 191 IPYAAPEVCAGGKYRGPPIDVWSSGIVLIAMLTGELPWDRASDSS 235
>ATG1_COLLN (P87248) Serine/threonine-protein kinase ATG1 (EC 2.7.11.1)| (Autophagy-related protein 1) (Colletotrichum lindemuthianum kinase 1) Length = 675 Score = 36.6 bits (83), Expect = 0.070 Identities = 18/43 (41%), Positives = 25/43 (58%) Frame = -3 Query: 652 YSAPEFAMSGTYTVKSDVYSFGVVMLELLTGRKPLDRSRERSE 524 Y APE Y K+D++S G V+ E++TGR P R+R E Sbjct: 236 YMAPEILRYERYDAKADLWSVGTVLYEMITGRPPF-RARNHVE 277
>PKN6_MYXXA (P54738) Serine/threonine-protein kinase pkn6 (EC 2.7.11.1)| Length = 710 Score = 36.6 bits (83), Expect = 0.070 Identities = 17/42 (40%), Positives = 25/42 (59%) Frame = -3 Query: 652 YSAPEFAMSGTYTVKSDVYSFGVVMLELLTGRKPLDRSRERS 527 Y PE + + DVY+ GVV+ ELLTG++P D + + S Sbjct: 185 YMPPEQLQAKAMDRRVDVYALGVVLYELLTGKRPFDATTDVS 226
>LATS1_HUMAN (O95835) Serine/threonine-protein kinase LATS1 (EC 2.7.11.1) (Large| tumor suppressor homolog 1) (WARTS protein kinase) (h-warts) Length = 1130 Score = 36.6 bits (83), Expect = 0.070 Identities = 24/70 (34%), Positives = 37/70 (52%), Gaps = 1/70 (1%) Frame = -3 Query: 652 YSAPEFAMSGTYTVKSDVYSFGVVMLELLTGRKP-LDRSRERSEQSLVGWATPQLHDIDA 476 Y APE + YT D +S GV++ E+L G+ P L ++ ++ ++ W T LH I Sbjct: 916 YIAPEVLLRTGYTQLCDWWSVGVILFEMLVGQPPFLAQTPLETQMKVINWQT-SLH-IPP 973 Query: 475 LAKMVDPAMD 446 AK+ A D Sbjct: 974 QAKLSPEASD 983
>KGP1A_RABIT (O77676) cGMP-dependent protein kinase 1, alpha isozyme (EC| 2.7.11.12) (CGK 1 alpha) (cGKI-alpha) Length = 670 Score = 36.6 bits (83), Expect = 0.070 Identities = 15/35 (42%), Positives = 23/35 (65%) Frame = -3 Query: 655 EYSAPEFAMSGTYTVKSDVYSFGVVMLELLTGRKP 551 EY APE ++ + + +D +S G++M ELLTG P Sbjct: 522 EYVAPEIILNKGHDISADYWSLGILMYELLTGSPP 556
>KGP1A_HUMAN (Q13976) cGMP-dependent protein kinase 1, alpha isozyme (EC| 2.7.11.12) (CGK 1 alpha) (cGKI-alpha) Length = 670 Score = 36.6 bits (83), Expect = 0.070 Identities = 15/35 (42%), Positives = 23/35 (65%) Frame = -3 Query: 655 EYSAPEFAMSGTYTVKSDVYSFGVVMLELLTGRKP 551 EY APE ++ + + +D +S G++M ELLTG P Sbjct: 522 EYVAPEIILNKGHDISADYWSLGILMYELLTGSPP 556
>KGP1A_BOVIN (P00516) cGMP-dependent protein kinase 1, alpha isozyme (EC| 2.7.11.12) (CGK 1 alpha) (cGKI-alpha) Length = 670 Score = 36.6 bits (83), Expect = 0.070 Identities = 15/35 (42%), Positives = 23/35 (65%) Frame = -3 Query: 655 EYSAPEFAMSGTYTVKSDVYSFGVVMLELLTGRKP 551 EY APE ++ + + +D +S G++M ELLTG P Sbjct: 522 EYVAPEIILNKGHDISADYWSLGILMYELLTGSPP 556
>PKN2_CLOAB (Q97IC2) Probable serine/threonine protein kinase CAC1728 (EC| 2.7.11.1) Length = 657 Score = 36.6 bits (83), Expect = 0.070 Identities = 15/36 (41%), Positives = 23/36 (63%) Frame = -3 Query: 652 YSAPEFAMSGTYTVKSDVYSFGVVMLELLTGRKPLD 545 Y +PE A ++D+YSFG+V+ E+ TG+ P D Sbjct: 175 YLSPEQAQGIPVDCRTDIYSFGIVLYEMATGKVPYD 210
>KGP1B_MOUSE (Q9Z0Z0) cGMP-dependent protein kinase 1, beta isozyme (EC| 2.7.11.12) (cGK 1 beta) (cGKI-beta) Length = 686 Score = 36.6 bits (83), Expect = 0.070 Identities = 15/35 (42%), Positives = 23/35 (65%) Frame = -3 Query: 655 EYSAPEFAMSGTYTVKSDVYSFGVVMLELLTGRKP 551 EY APE ++ + + +D +S G++M ELLTG P Sbjct: 538 EYVAPEIILNKGHDISADYWSLGILMYELLTGSPP 572
>KGP1B_HUMAN (P14619) cGMP-dependent protein kinase 1, beta isozyme (EC| 2.7.11.12) (cGK 1 beta) (cGKI-beta) Length = 686 Score = 36.6 bits (83), Expect = 0.070 Identities = 15/35 (42%), Positives = 23/35 (65%) Frame = -3 Query: 655 EYSAPEFAMSGTYTVKSDVYSFGVVMLELLTGRKP 551 EY APE ++ + + +D +S G++M ELLTG P Sbjct: 538 EYVAPEIILNKGHDISADYWSLGILMYELLTGSPP 572
>KGP1B_BOVIN (P21136) cGMP-dependent protein kinase 1, beta isozyme (EC| 2.7.11.12) (cGK 1 beta) (cGKI-beta) Length = 686 Score = 36.6 bits (83), Expect = 0.070 Identities = 15/35 (42%), Positives = 23/35 (65%) Frame = -3 Query: 655 EYSAPEFAMSGTYTVKSDVYSFGVVMLELLTGRKP 551 EY APE ++ + + +D +S G++M ELLTG P Sbjct: 538 EYVAPEIILNKGHDISADYWSLGILMYELLTGSPP 572
>FLT3_MOUSE (Q00342) FL cytokine receptor precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor flk-2) (Fetal liver kinase 2) (Tyrosine-protein kinase FLT3) Length = 992 Score = 36.2 bits (82), Expect = 0.091 Identities = 13/32 (40%), Positives = 24/32 (75%) Frame = -3 Query: 658 LEYSAPEFAMSGTYTVKSDVYSFGVVMLELLT 563 +++ APE G YT+KSDV+S+G+++ E+ + Sbjct: 855 VKWMAPESLFEGIYTIKSDVWSYGILLWEIFS 886
>PKN1_THETN (Q8R9T6) Probable serine/threonine-protein kinase Sps1 (EC| 2.7.11.1) Length = 625 Score = 36.2 bits (82), Expect = 0.091 Identities = 14/36 (38%), Positives = 23/36 (63%) Frame = -3 Query: 652 YSAPEFAMSGTYTVKSDVYSFGVVMLELLTGRKPLD 545 Y +PE A ++D+YS G+V+ E+LTG+ P + Sbjct: 176 YFSPEQAKGSIVDERTDIYSLGIVLFEMLTGKVPFE 211
>EPHB6_PANTR (P0C0K6) Ephrin type-B receptor 6 precursor (Tyrosine-protein| kinase-defective receptor EPH-6) Length = 1005 Score = 36.2 bits (82), Expect = 0.091 Identities = 16/37 (43%), Positives = 26/37 (70%), Gaps = 1/37 (2%) Frame = -3 Query: 658 LEYSAPEFAMSGTYTVKSDVYSFGVVMLELLT-GRKP 551 L ++APE G +T SDV+SFG++M E+++ G +P Sbjct: 809 LRWAAPEVIAHGKHTTSSDVWSFGILMWEVMSYGERP 845
>PKNA_MYCLE (P54743) Probable serine/threonine-protein kinase pknA (EC| 2.7.11.1) Length = 437 Score = 36.2 bits (82), Expect = 0.091 Identities = 16/35 (45%), Positives = 24/35 (68%) Frame = -3 Query: 655 EYSAPEFAMSGTYTVKSDVYSFGVVMLELLTGRKP 551 +Y APE A+ T SDVYS GV+ E+++G++P Sbjct: 182 QYIAPEQALGHDATPASDVYSLGVIGYEVVSGKRP 216
>KS6A_CAEEL (Q21734) Putative ribosomal protein S6 kinase alpha (EC 2.7.11.1)| Length = 784 Score = 36.2 bits (82), Expect = 0.091 Identities = 34/121 (28%), Positives = 58/121 (47%), Gaps = 18/121 (14%) Frame = -3 Query: 658 LEYSAPEFAMSGTYTVKSDVYSFGVVMLELLTGRKPLDRSRERSEQ---------SLVGW 506 +EY APE +++ +D +S GV+M E+LTG P + R+R++ S+ + Sbjct: 268 VEYMAPEVINRRGHSMAADFWSLGVLMFEMLTGHLPF-QGRDRNDTMTQILKAKLSMPHF 326 Query: 505 ATPQLHD-IDALAK-----MVDPAMDGMYPAKSLSRFADI---IALSVQPEPEFRPPISE 353 T + + AL K + DG+ K + FA I L+ + +P F+P +S Sbjct: 327 LTQEAQSLLRALFKRNSQNRLGAGPDGVEEIKRHAFFAKIDFVKLLNKEIDPPFKPALST 386 Query: 352 V 350 V Sbjct: 387 V 387
>CDK4_XENLA (Q91727) Cell division protein kinase 4 (EC 2.7.11.22)| (Cyclin-dependent kinase 4) Length = 319 Score = 36.2 bits (82), Expect = 0.091 Identities = 34/124 (27%), Positives = 50/124 (40%) Frame = -3 Query: 658 LEYSAPEFAMSGTYTVKSDVYSFGVVMLELLTGRKPLDRSRERSEQSLVGWATPQLHDID 479 L Y APE + TY DV+S G + E+ RKPL ++Q ++ DI Sbjct: 178 LWYRAPEVLLQSTYATPVDVWSAGCIFAEMFK-RKPLFCGNSEADQLC------KIFDII 230 Query: 478 ALAKMVDPAMDGMYPAKSLSRFADIIALSVQPEPEFRPPISEVVQQLVRLMQRASMLRRQ 299 L + +D P + S + QP +F P I + L+ M S +R Sbjct: 231 GLPSEEEWPVDVTLPRSAFS------PRTQQPVDKFVPEIDAMGADLLLAMLTFSPQKRI 284 Query: 298 SGDD 287 S D Sbjct: 285 SASD 288
>EPHB6_HUMAN (O15197) Ephrin type-B receptor 6 precursor (Tyrosine-protein| kinase-defective receptor EPH-6) (HEP) Length = 1006 Score = 36.2 bits (82), Expect = 0.091 Identities = 16/37 (43%), Positives = 26/37 (70%), Gaps = 1/37 (2%) Frame = -3 Query: 658 LEYSAPEFAMSGTYTVKSDVYSFGVVMLELLT-GRKP 551 L ++APE G +T SDV+SFG++M E+++ G +P Sbjct: 810 LRWAAPEVIAHGKHTTSSDVWSFGILMWEVMSYGERP 846
>EPHA2_MOUSE (Q03145) Ephrin type-A receptor 2 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor ECK) (Epithelial cell kinase) (MPK-5) (SEK-2) Length = 977 Score = 36.2 bits (82), Expect = 0.091 Identities = 33/137 (24%), Positives = 57/137 (41%), Gaps = 1/137 (0%) Frame = -3 Query: 658 LEYSAPEFAMSGTYTVKSDVYSFGVVMLELLT-GRKPLDRSRERSEQSLVGWATPQLHDI 482 + ++APE +T SDV+S+G+VM E++T G +P W H++ Sbjct: 782 IRWTAPEAISYRKFTSASDVWSYGIVMWEVMTYGERPY-------------WELSN-HEV 827 Query: 481 DALAKMVDPAMDGMYPAKSLSRFADIIALSVQPEPEFRPPISEVVQQLVRLMQRASMLRR 302 K ++ P S ++ Q E RP +++V L +L++ L+ Sbjct: 828 ---MKAINDGFRLPTPMDCPSAIYQLMMQCWQQERSRRPKFADIVSILDKLIRAPDSLKT 884 Query: 301 QSGDDLGSSYRAPEREG 251 + D S R P G Sbjct: 885 LADFDPRVSIRLPSTSG 901
>SPKA_SYNY3 (Q9FAB3) Serine/threonine-protein kinase A (EC 2.7.11.1)| Length = 521 Score = 36.2 bits (82), Expect = 0.091 Identities = 17/37 (45%), Positives = 22/37 (59%) Frame = -3 Query: 658 LEYSAPEFAMSGTYTVKSDVYSFGVVMLELLTGRKPL 548 L Y +PE +SD+YS GV+M E+LTG PL Sbjct: 192 LAYCSPEQMEGKELDSRSDIYSLGVMMYEMLTGEMPL 228
>PKNB_MYCTU (P0A5S4) Probable serine/threonine-protein kinase pknB (EC| 2.7.11.1) Length = 626 Score = 36.2 bits (82), Expect = 0.091 Identities = 16/35 (45%), Positives = 22/35 (62%) Frame = -3 Query: 655 EYSAPEFAMSGTYTVKSDVYSFGVVMLELLTGRKP 551 +Y +PE A + +SDVYS G V+ E+LTG P Sbjct: 181 QYLSPEQARGDSVDARSDVYSLGCVLYEVLTGEPP 215
>PKNB_MYCBO (P0A5S5) Probable serine/threonine-protein kinase pknB (EC| 2.7.11.1) Length = 626 Score = 36.2 bits (82), Expect = 0.091 Identities = 16/35 (45%), Positives = 22/35 (62%) Frame = -3 Query: 655 EYSAPEFAMSGTYTVKSDVYSFGVVMLELLTGRKP 551 +Y +PE A + +SDVYS G V+ E+LTG P Sbjct: 181 QYLSPEQARGDSVDARSDVYSLGCVLYEVLTGEPP 215
>SKH1_SCHPO (Q9Y884) MAP kinase kinase skh1/pek1 (EC 2.7.12.2)| Length = 363 Score = 36.2 bits (82), Expect = 0.091 Identities = 14/34 (41%), Positives = 22/34 (64%) Frame = -3 Query: 652 YSAPEFAMSGTYTVKSDVYSFGVVMLELLTGRKP 551 Y APE G+YT+ SD++S G+ ++E+ R P Sbjct: 245 YMAPERISGGSYTISSDIWSLGLTLMEVALNRFP 278
>SEA_AVIET (P23049) Tyrosine-protein kinase transforming protein SEA (EC| 2.7.10.2) Length = 370 Score = 36.2 bits (82), Expect = 0.091 Identities = 37/114 (32%), Positives = 51/114 (44%), Gaps = 3/114 (2%) Frame = -3 Query: 658 LEYSAPEFAMSGTYTVKSDVYSFGVVMLELLT-GRKPLDR--SRERSEQSLVGWATPQLH 488 + + A E + +T KSDV+SFGV+M ELLT G P + + L G PQ Sbjct: 229 VRWMALESLQTQKFTTKSDVWSFGVLMWELLTRGASPYPEVDPYDMARYLLRGRRLPQ-- 286 Query: 487 DIDALAKMVDPAMDGMYPAKSLSRFADIIALSVQPEPEFRPPISEVVQQLVRLM 326 P D +Y LS +A P PE RP S +V +L R++ Sbjct: 287 --------PQPCPDTLY-GVMLSCWA--------PTPEERPSFSGLVCELERVL 323
>FLT3_HUMAN (P36888) FL cytokine receptor precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor FLT3) (Stem cell tyrosine kinase 1) (STK-1) (CD135 antigen) Length = 993 Score = 36.2 bits (82), Expect = 0.091 Identities = 13/32 (40%), Positives = 24/32 (75%) Frame = -3 Query: 658 LEYSAPEFAMSGTYTVKSDVYSFGVVMLELLT 563 +++ APE G YT+KSDV+S+G+++ E+ + Sbjct: 852 VKWMAPESLFEGIYTIKSDVWSYGILLWEIFS 883
>MP2K2_HUMAN (P36507) Dual specificity mitogen-activated protein kinase kinase 2| (EC 2.7.12.2) (MAP kinase kinase 2) (MAPKK 2) (ERK activator kinase 2) (MAPK/ERK kinase 2) (MEK2) Length = 400 Score = 36.2 bits (82), Expect = 0.091 Identities = 16/48 (33%), Positives = 28/48 (58%) Frame = -3 Query: 652 YSAPEFAMSGTYTVKSDVYSFGVVMLELLTGRKPLDRSRERSEQSLVG 509 Y APE Y+V+SD++S G+ ++EL GR P+ + +++ G Sbjct: 233 YMAPERLQGTHYSVQSDIWSMGLSLVELAVGRYPIPPPDAKELEAIFG 280
>ATG1_NEUCR (Q7RX99) Serine/threonine-protein kinase atg-1 (EC 2.7.11.1)| (Autophagy-related protein 1) Length = 932 Score = 36.2 bits (82), Expect = 0.091 Identities = 16/38 (42%), Positives = 22/38 (57%) Frame = -3 Query: 652 YSAPEFAMSGTYTVKSDVYSFGVVMLELLTGRKPLDRS 539 Y APE Y K+D++S G V+ E++TGR P S Sbjct: 237 YMAPEILRYEKYDAKADLWSVGTVLYEMVTGRPPFKAS 274
>TXK_HUMAN (P42681) Tyrosine-protein kinase TXK (EC 2.7.10.2)| Length = 527 Score = 36.2 bits (82), Expect = 0.091 Identities = 17/39 (43%), Positives = 27/39 (69%), Gaps = 1/39 (2%) Frame = -3 Query: 658 LEYSAPEFAMSGTYTVKSDVYSFGVVMLELLT-GRKPLD 545 +++S PE + Y+ KSDV+SFGV+M E+ T G+ P + Sbjct: 430 IKWSPPEVFLFNKYSSKSDVWSFGVLMWEVFTEGKMPFE 468
>NRKA_TRYBB (Q08942) Putative serine/threonine-protein kinase A (EC 2.7.11.1)| Length = 431 Score = 35.8 bits (81), Expect = 0.12 Identities = 28/103 (27%), Positives = 43/103 (41%) Frame = -3 Query: 652 YSAPEFAMSGTYTVKSDVYSFGVVMLELLTGRKPLDRSRERSEQSLVGWATPQLHDIDAL 473 Y APE + Y K+DV+S GV++ E++ +KP S + S V L Sbjct: 190 YLAPELWNNKRYNKKADVWSLGVLLYEIMGMKKPFSASNLKGLMSKV------------L 237 Query: 472 AKMVDPAMDGMYPAKSLSRFADIIALSVQPEPEFRPPISEVVQ 344 A P D S F ++ + +P RP + E+ Q Sbjct: 238 AGTYAPLPDSF-----SSEFKRVVDGILVADPNDRPSVREIFQ 275
>FUZ7_USTMA (Q99078) Dual specificity protein kinase FUZ7 (EC 2.7.12.2)| Length = 435 Score = 35.8 bits (81), Expect = 0.12 Identities = 16/40 (40%), Positives = 24/40 (60%) Frame = -3 Query: 652 YSAPEFAMSGTYTVKSDVYSFGVVMLELLTGRKPLDRSRE 533 Y +PE Y+VKSDV+S GV ++++ GR P + E Sbjct: 270 YMSPERIQGDQYSVKSDVWSLGVSIIDVALGRFPFAENEE 309
>ATG1_USTMA (Q4P0K0) Serine/threonine-protein kinase ATG1 (EC 2.7.11.1)| (Autophagy-related protein 1) Length = 990 Score = 35.8 bits (81), Expect = 0.12 Identities = 33/126 (26%), Positives = 54/126 (42%) Frame = -3 Query: 652 YSAPEFAMSGTYTVKSDVYSFGVVMLELLTGRKPLDRSRERSEQSLVGWATPQLHDIDAL 473 Y APE Y K+D++S G V+ E+ G+ P R + L+ ++ + Sbjct: 218 YMAPEILRFEKYDAKADLWSVGAVLFEMTVGKPPF---RAANHVELL----KRIERGEDK 270 Query: 472 AKMVDPAMDGMYPAKSLSRFADIIALSVQPEPEFRPPISEVVQQLVRLMQRASMLRRQSG 293 K D G ++ R + + P P P+SE V+ L+R + R + R S Sbjct: 271 IKFPDERSAGSLAREAARR--QELGEAPLPPPH---PVSEDVKILIRQLLRQRPVSRMSF 325 Query: 292 DDLGSS 275 DD +S Sbjct: 326 DDFFAS 331
>PKNA2_BIFLO (Q8G4G1) Probable serine/threonine-protein kinase pknA2 (EC| 2.7.11.1) Length = 757 Score = 35.8 bits (81), Expect = 0.12 Identities = 15/36 (41%), Positives = 22/36 (61%) Frame = -3 Query: 652 YSAPEFAMSGTYTVKSDVYSFGVVMLELLTGRKPLD 545 Y APE + T + D+YS G++ E+LTG+ P D Sbjct: 182 YLAPEMIENNQATAQGDLYSVGIMAWEMLTGKVPFD 217
>IKKB_RAT (Q9QY78) Inhibitor of nuclear factor kappa B kinase beta subunit| (EC 2.7.11.1) (I-kappa-B-kinase beta) (IkBKB) (IKK-beta) (IKK-B) (I-kappa-B kinase 2) (IKK2) (Nuclear factor NF-kappa-B inhibitor kinase beta) (NFKBIKB) Length = 757 Score = 35.8 bits (81), Expect = 0.12 Identities = 20/59 (33%), Positives = 29/59 (49%), Gaps = 10/59 (16%) Frame = -3 Query: 658 LEYSAPEFAMSGTYTVKSDVYSFGVVMLELLTGRKPL----------DRSRERSEQSLV 512 L+Y APE YTV D +SFG + E +TG +P + R++SE +V Sbjct: 186 LQYLAPELLEQQKYTVTVDYWSFGTLAFECITGFRPFLPNWQPVQWHSKVRQKSEVDIV 244
>IKKB_MOUSE (O88351) Inhibitor of nuclear factor kappa B kinase beta subunit| (EC 2.7.11.10) (I-kappa-B-kinase beta) (IkBKB) (IKK-beta) (IKK-B) (I-kappa-B kinase 2) (IKK2) (Nuclear factor NF-kappa-B inhibitor kinase beta) (NFKBIKB) Length = 757 Score = 35.8 bits (81), Expect = 0.12 Identities = 20/59 (33%), Positives = 29/59 (49%), Gaps = 10/59 (16%) Frame = -3 Query: 658 LEYSAPEFAMSGTYTVKSDVYSFGVVMLELLTGRKPL----------DRSRERSEQSLV 512 L+Y APE YTV D +SFG + E +TG +P + R++SE +V Sbjct: 186 LQYLAPELLEQQKYTVTVDYWSFGTLAFECITGFRPFLPNWQPVQWHSKVRQKSEVDIV 244
>RAF1_MOUSE (Q99N57) RAF proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (Raf-1) (C-RAF) (cRaf) Length = 648 Score = 35.8 bits (81), Expect = 0.12 Identities = 31/125 (24%), Positives = 54/125 (43%), Gaps = 3/125 (2%) Frame = -3 Query: 619 YTVKSDVYSFGVVMLELLTGRKPLDRSRERSEQSLV---GWATPQLHDIDALAKMVDPAM 449 ++ +SDVYS+G+V+ EL+ G P R + + G+A+P D+ L K AM Sbjct: 525 FSFQSDVYSYGIVLYELMAGELPYAHINNRDQIIFMVGRGYASP---DLSRLYKNCPKAM 581 Query: 448 DGMYPAKSLSRFADIIALSVQPEPEFRPPISEVVQQLVRLMQRASMLRRQSGDDLGSSYR 269 ++A V+ E RP +++ + L + R + + S +R Sbjct: 582 ------------KRLVADCVKKVKEERPLFPQILSSIELLQHSLPKINRSASEP--SLHR 627 Query: 268 APERE 254 A E Sbjct: 628 AAHTE 632
>IKKB_DROME (Q9VEZ5) Inhibitor of nuclear factor kappa B kinase beta subunit| (EC 2.7.11.1) (DmIKK-beta) (Immune response deficient protein 5) (IKK-like protein) (Lipopolysaccharide-activated kinase) (DLAK) (Cactus kinase IKK) Length = 751 Score = 35.8 bits (81), Expect = 0.12 Identities = 16/34 (47%), Positives = 21/34 (61%) Frame = -3 Query: 652 YSAPEFAMSGTYTVKSDVYSFGVVMLELLTGRKP 551 Y APE +G Y D++SFGV+ EL+TG P Sbjct: 228 YYAPEVVENGFYNSTVDLWSFGVIAYELVTGELP 261
>E2AK1_RABIT (P33279) Eukaryotic translation initiation factor 2-alpha kinase 1| (EC 2.7.11.1) (Heme-regulated eukaryotic initiation factor eIF-2-alpha kinase) (Heme-regulated inhibitor) (Heme-controlled repressor) (HCR) (Hemin-sensitive initiation factor Length = 626 Score = 35.8 bits (81), Expect = 0.12 Identities = 18/43 (41%), Positives = 25/43 (58%) Frame = -3 Query: 652 YSAPEFAMSGTYTVKSDVYSFGVVMLELLTGRKPLDRSRERSE 524 Y++PE Y KSD+YS GV++LEL +P ER+E Sbjct: 491 YASPEQLEGSEYDAKSDMYSVGVILLELF---QPFGTEMERAE 530
>KPK19_ARATH (Q39030) Serine/threonine-protein kinase AtPK19 (EC 2.7.11.1)| (Ribosomal-protein S6 kinase homolog) Length = 471 Score = 35.8 bits (81), Expect = 0.12 Identities = 16/48 (33%), Positives = 28/48 (58%) Frame = -3 Query: 655 EYSAPEFAMSGTYTVKSDVYSFGVVMLELLTGRKPLDRSRERSEQSLV 512 EY APE + +D +S G+++ E+LTG+ P S+ + +Q +V Sbjct: 302 EYMAPEIVRGKGHDKAADWWSVGILLYEMLTGKPPFLGSKGKIQQKIV 349
>IKKB_HUMAN (O14920) Inhibitor of nuclear factor kappa B kinase beta subunit| (EC 2.7.11.10) (I-kappa-B-kinase beta) (IkBKB) (IKK-beta) (IKK-B) (I-kappa-B kinase 2) (IKK2) (Nuclear factor NF-kappa-B inhibitor kinase beta) (NFKBIKB) Length = 756 Score = 35.8 bits (81), Expect = 0.12 Identities = 20/59 (33%), Positives = 29/59 (49%), Gaps = 10/59 (16%) Frame = -3 Query: 658 LEYSAPEFAMSGTYTVKSDVYSFGVVMLELLTGRKPL----------DRSRERSEQSLV 512 L+Y APE YTV D +SFG + E +TG +P + R++SE +V Sbjct: 186 LQYLAPELLEQQKYTVTVDYWSFGTLAFECITGFRPFLPNWQPVQWHSKVRQKSEVDIV 244
>STK25_MOUSE (Q9Z2W1) Serine/threonine-protein kinase 25 (EC 2.7.11.1) (Sterile| 20/oxidant stress-response kinase 1) (Ste20/oxidant stress response kinase 1) (SOK-1) (Ste20-like kinase) Length = 426 Score = 35.8 bits (81), Expect = 0.12 Identities = 27/120 (22%), Positives = 47/120 (39%), Gaps = 5/120 (4%) Frame = -3 Query: 652 YSAPEFAMSGTYTVKSDVYSFGVVMLELLTGRKPLDRSRERSEQSLVGWATPQLHDIDAL 473 + APE Y K+D++S G+ +EL G P LH + L Sbjct: 181 WMAPEVIKQSAYDFKADIWSLGITAIELAKGEPP----------------NSDLHPMRVL 224 Query: 472 ---AKMVDPAMDGMYPAKSLSRFADIIALSVQPEPEFRPPISEVVQQ--LVRLMQRASML 308 K P ++G + F + + + +P FRP E+++ + R ++ S L Sbjct: 225 FLIPKNNPPTLEGHHS----KPFKEFVEACLNKDPRFRPTAKELLKHKFITRYTKKTSFL 280
>NEK9_XENLA (Q7ZZC8) Serine/threonine-protein kinase Nek9 (EC 2.7.11.1)| (NimA-related protein kinase 9) (XNek9) (Nercc1 kinase) Length = 944 Score = 35.8 bits (81), Expect = 0.12 Identities = 26/122 (21%), Positives = 52/122 (42%), Gaps = 1/122 (0%) Frame = -3 Query: 658 LEYSAPEFAMSGTYTVKSDVYSFGVVMLELLTGRKPLDRSRERSEQSLVGWATPQLHDID 479 L Y +PE Y+ KSD+++ G V+ ELLT + D + + ++ Sbjct: 197 LYYMSPEICQGVKYSFKSDIWAVGCVLYELLTLTRTFDAT----------------NPLN 240 Query: 478 ALAKMVDPAMD-GMYPAKSLSRFADIIALSVQPEPEFRPPISEVVQQLVRLMQRASMLRR 302 K+V G+ +++ ++ +PE RP E++++ + +R M + Sbjct: 241 LCVKIVQGNWAVGLDNTVYTQELIEVVHACLEQDPEKRPTADEILERPILSWRRRDMEEK 300 Query: 301 QS 296 S Sbjct: 301 VS 302
>STE20_CANAL (Q92212) Serine/threonine-protein kinase STE20 homolog (EC 2.7.11.1)| Length = 1230 Score = 35.8 bits (81), Expect = 0.12 Identities = 20/62 (32%), Positives = 35/62 (56%), Gaps = 1/62 (1%) Frame = -3 Query: 652 YSAPEFAMSGTYTVKSDVYSFGVVMLELLTGRKP-LDRSRERSEQSLVGWATPQLHDIDA 476 + APE Y K DV+S G++++E+L G P L+ + R+ + TP+L D ++ Sbjct: 1114 WMAPEIVSRKEYGPKVDVWSLGIMIIEMLEGEPPYLNETPLRALYLIATNGTPKLKDPES 1173 Query: 475 LA 470 L+ Sbjct: 1174 LS 1175
>KPK1_ARATH (P42818) Serine/threonine-protein kinase AtPK1/AtPK6 (EC 2.7.11.1)| Length = 465 Score = 35.8 bits (81), Expect = 0.12 Identities = 16/48 (33%), Positives = 28/48 (58%) Frame = -3 Query: 655 EYSAPEFAMSGTYTVKSDVYSFGVVMLELLTGRKPLDRSRERSEQSLV 512 EY APE + +D +S G+++ E+LTG+ P S+ + +Q +V Sbjct: 296 EYMAPEIVRGKGHDKAADWWSVGILLYEMLTGKPPFLGSKGKIQQKIV 343
>HUNK_PANTR (Q68UT7) Hormonally up-regulated neu tumor-associated kinase (EC| 2.7.11.1) Length = 714 Score = 35.8 bits (81), Expect = 0.12 Identities = 30/103 (29%), Positives = 45/103 (43%), Gaps = 1/103 (0%) Frame = -3 Query: 652 YSAPEFAMSGTYTVKSDVYSFGVVMLELLTGRKPLDRSRERSEQSLVGWATPQLHDIDAL 473 Y+APE Y K DV+S GV M +LTG P T + + AL Sbjct: 229 YAAPELLARKKYGPKIDVWSIGVNMYAMLTGTLPF---------------TVEPFSLRAL 273 Query: 472 -AKMVDPAMDGMYPAKSLSRFADIIALSVQPEPEFRPPISEVV 347 KMVD M+ + P + + + ++P+P RP I + + Sbjct: 274 YQKMVDKEMNPL-PTQLSTGAISFLRSLLEPDPVKRPNIQQAL 315
>HUNK_HUMAN (P57058) Hormonally up-regulated neu tumor-associated kinase (EC| 2.7.11.1) (Serine/threonine-protein kinase MAK-V) (B19) Length = 714 Score = 35.8 bits (81), Expect = 0.12 Identities = 30/103 (29%), Positives = 45/103 (43%), Gaps = 1/103 (0%) Frame = -3 Query: 652 YSAPEFAMSGTYTVKSDVYSFGVVMLELLTGRKPLDRSRERSEQSLVGWATPQLHDIDAL 473 Y+APE Y K DV+S GV M +LTG P T + + AL Sbjct: 229 YAAPELLARKKYGPKIDVWSIGVNMYAMLTGTLPF---------------TVEPFSLRAL 273 Query: 472 -AKMVDPAMDGMYPAKSLSRFADIIALSVQPEPEFRPPISEVV 347 KMVD M+ + P + + + ++P+P RP I + + Sbjct: 274 YQKMVDKEMNPL-PTQLSTGAISFLRSLLEPDPVKRPNIQQAL 315
>XMRK_XIPMA (P13388) Melanoma receptor tyrosine-protein kinase precursor (EC| 2.7.10.1) Length = 1167 Score = 35.4 bits (80), Expect = 0.15 Identities = 18/39 (46%), Positives = 27/39 (69%), Gaps = 1/39 (2%) Frame = -3 Query: 658 LEYSAPEFAMSGTYTVKSDVYSFGVVMLELLT-GRKPLD 545 +++ A E + TYT +SDV+S+GV + EL+T G KP D Sbjct: 876 IKWMALESILQWTYTHQSDVWSYGVTVWELMTFGSKPYD 914
>KS6A1_HUMAN (Q15418) Ribosomal protein S6 kinase alpha-1 (EC 2.7.11.1)| (S6K-alpha 1) (90 kDa ribosomal protein S6 kinase 1) (p90-RSK 1) (Ribosomal S6 kinase 1) (RSK-1) (pp90RSK1) (MAP kinase-activated protein kinase 1a) (MAPKAPK1A) Length = 735 Score = 35.4 bits (80), Expect = 0.15 Identities = 16/49 (32%), Positives = 27/49 (55%) Frame = -3 Query: 658 LEYSAPEFAMSGTYTVKSDVYSFGVVMLELLTGRKPLDRSRERSEQSLV 512 +EY APE ++ +D +S+GV+M E+LTG P + +L+ Sbjct: 226 VEYMAPEVVNRQGHSHSADWWSYGVLMFEMLTGSLPFQGKDRKETMTLI 274
>INSR_XENLA (Q9PVZ4) Insulin receptor precursor (EC 2.7.10.1) (IR) (Xe-InsR)| (XTK-1b) [Contains: Insulin receptor alpha subunit; Insulin receptor beta subunit] Length = 1362 Score = 35.4 bits (80), Expect = 0.15 Identities = 27/107 (25%), Positives = 45/107 (42%) Frame = -3 Query: 658 LEYSAPEFAMSGTYTVKSDVYSFGVVMLELLTGRKPLDRSRERSEQSLVGWATPQLHDID 479 + + +PE G +T SDV+SFGVV+ E+ + +EQ G + Q Sbjct: 1189 VRWMSPESLKDGVFTAFSDVWSFGVVLWEITS----------LAEQPYQGLSNEQ----- 1233 Query: 478 ALAKMVDPAMDGMYPAKSLSRFADIIALSVQPEPEFRPPISEVVQQL 338 + K V +P R ++ + Q P+ RP E++ L Sbjct: 1234 -VLKFVMDGGSLDHPENCPPRLHSLMQMCWQYNPKMRPTFLEIIDML 1279
>PKN1_COREF (Q8FUI5) Probable serine/threonine protein kinase CE0033 (EC| 2.7.11.1) Length = 660 Score = 35.4 bits (80), Expect = 0.15 Identities = 16/37 (43%), Positives = 23/37 (62%) Frame = -3 Query: 655 EYSAPEFAMSGTYTVKSDVYSFGVVMLELLTGRKPLD 545 +Y +PE A +SDVY+ G V+ EL+TGR P + Sbjct: 179 QYLSPEQARGKPADARSDVYAAGCVLYELVTGRPPFE 215
>KS6A6_HUMAN (Q9UK32) Ribosomal protein S6 kinase alpha-6 (EC 2.7.11.1)| (S6K-alpha 6) (90 kDa ribosomal protein S6 kinase 6) (p90-RSK 6) (Ribosomal S6 kinase 4) (RSK-4) (pp90RSK4) Length = 745 Score = 35.4 bits (80), Expect = 0.15 Identities = 17/45 (37%), Positives = 29/45 (64%) Frame = -3 Query: 658 LEYSAPEFAMSGTYTVKSDVYSFGVVMLELLTGRKPLDRSRERSE 524 +EY APE ++ +D +S+GV+M E+LTG P + ++R+E Sbjct: 237 VEYMAPEVVNRRGHSQSADWWSYGVLMFEMLTGTLPF-QGKDRNE 280
>ARAF_PIG (O19004) A-Raf proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (A-Raf-1) Length = 606 Score = 35.4 bits (80), Expect = 0.15 Identities = 18/51 (35%), Positives = 29/51 (56%), Gaps = 3/51 (5%) Frame = -3 Query: 619 YTVKSDVYSFGVVMLELLTGRKPLDRSRERSEQSLV---GWATPQLHDIDA 476 Y+ +SDVY++GVV+ EL+TG P R + + G+ +P L I + Sbjct: 486 YSFQSDVYAYGVVLYELMTGSLPYSHIGSRDQIIFMVGRGYLSPDLSKISS 536
>Y31E_CAEEL (Q8MYQ1) Putative serine/threonine-protein kinase F31E3.2 (EC| 2.7.11.1) Length = 441 Score = 35.4 bits (80), Expect = 0.15 Identities = 20/56 (35%), Positives = 31/56 (55%), Gaps = 2/56 (3%) Frame = -3 Query: 658 LEYSAPEFAMSGTYTVKSDVYSFGVVMLELLTGRKPLDRSRERSEQSL--VGWATP 497 L+Y +P+ A GTY+ D +S GV++ LLTG P S +L + ++TP Sbjct: 291 LQYMSPDVASGGTYSHYVDWWSLGVLLHILLTGIYPYPNSEATHHANLKFIDYSTP 346
>PKPA_PHYBL (Q01577) Serine/threonine-protein kinase pkpA (EC 2.7.11.1)| Length = 613 Score = 35.4 bits (80), Expect = 0.15 Identities = 15/35 (42%), Positives = 21/35 (60%) Frame = -3 Query: 655 EYSAPEFAMSGTYTVKSDVYSFGVVMLELLTGRKP 551 E+ APE Y K D+Y+FG+ +LE+ TG P Sbjct: 178 EFMAPEMYEEQGYNEKVDIYAFGMCLLEMATGEYP 212
>FGFR1_DROME (Q07407) Fibroblast growth factor receptor homolog 1 precursor (EC| 2.7.10.1) (Protein heartless) Length = 729 Score = 35.4 bits (80), Expect = 0.15 Identities = 26/113 (23%), Positives = 50/113 (44%), Gaps = 1/113 (0%) Frame = -3 Query: 658 LEYSAPEFAMSGTYTVKSDVYSFGVVMLELLT-GRKPLDRSRERSEQSLVGWATPQLHDI 482 +++ APE Y KSDV+S+G+++ E++T G++P P + Sbjct: 597 IKWMAPESLQEKFYDSKSDVWSYGILLWEIMTYGQQPY----------------PTIMSA 640 Query: 481 DALAKMVDPAMDGMYPAKSLSRFADIIALSVQPEPEFRPPISEVVQQLVRLMQ 323 + L + PAK ++ + RPP +E+V+ + +L+Q Sbjct: 641 EELYTYLMSGQRMEKPAKCSMNIYILMRQCWHFNADDRPPFTEIVEYMDKLLQ 693
>EPA4A_BRARE (O13148) Ephrin type-A receptor 4a (EC 2.7.10.1) (Tyrosine-protein| kinase receptor ZEK2) (EPH-like kinase 2) (Fragment) Length = 292 Score = 35.4 bits (80), Expect = 0.15 Identities = 33/126 (26%), Positives = 55/126 (43%), Gaps = 3/126 (2%) Frame = -3 Query: 658 LEYSAPEFAMSGTYTVKSDVYSFGVVMLELLT-GRKPLDRSRERSEQSLVGWATPQLHDI 482 + ++APE +T SDV+S+G+VM E+++ G +P W I Sbjct: 171 IRWTAPEAITYRKFTSASDVWSYGIVMWEVMSYGERPY-------------WDMSNQDVI 217 Query: 481 DALAK--MVDPAMDGMYPAKSLSRFADIIALSVQPEPEFRPPISEVVQQLVRLMQRASML 308 A+ + + P MD P D Q E RP S++V L +L++ + L Sbjct: 218 KAIEEGYRLPPPMD--CPVSLHQLMLD----CWQKERAERPKFSQIVNMLDKLIRNPNSL 271 Query: 307 RRQSGD 290 +R G+ Sbjct: 272 KRTGGE 277
>KS6AA_CHICK (P18652) Ribosomal protein S6 kinase 2 alpha (EC 2.7.11.1)| (Ribosomal protein S6 kinase II alpha) (S6KII-alpha) (P90-RSK) (MAP kinase-activated protein kinase 1) (MAPK-activated protein kinase 1) (MAPKAP kinase 1) (MAPKAPK-1) Length = 752 Score = 35.4 bits (80), Expect = 0.15 Identities = 16/49 (32%), Positives = 27/49 (55%) Frame = -3 Query: 658 LEYSAPEFAMSGTYTVKSDVYSFGVVMLELLTGRKPLDRSRERSEQSLV 512 +EY APE ++ +D +S+GV+M E+LTG P + +L+ Sbjct: 244 VEYMAPEVVNRQGHSHSADWWSYGVLMFEMLTGSLPFQGKDRKETMTLI 292
>HT1_ARATH (Q2MHE4) Serine/threonine-protein kinase HT1 (EC 2.7.11.1) (High| leaf temperature protein 1) Length = 390 Score = 35.4 bits (80), Expect = 0.15 Identities = 17/34 (50%), Positives = 20/34 (58%) Frame = -3 Query: 652 YSAPEFAMSGTYTVKSDVYSFGVVMLELLTGRKP 551 + APE YT K DVYSFG+V+ EL T P Sbjct: 252 WMAPEMIKEKPYTRKVDVYSFGIVLWELTTALLP 285
>PTK6_MOUSE (Q64434) Tyrosine-protein kinase 6 (EC 2.7.10.2) (SRC-related| intestinal kinase) Length = 451 Score = 35.4 bits (80), Expect = 0.15 Identities = 16/36 (44%), Positives = 27/36 (75%), Gaps = 1/36 (2%) Frame = -3 Query: 655 EYSAPEFAMSGTYTVKSDVYSFGVVMLELLT-GRKP 551 +++APE G Y++KSDV+SFGV++ E+ + G+ P Sbjct: 352 KWTAPEALSRGHYSIKSDVWSFGVLLHEIFSRGQMP 387
>KS6AA_XENLA (P10665) Ribosomal protein S6 kinase 2 alpha (EC 2.7.11.1)| (Ribosomal protein S6 kinase II alpha) (S6KII-alpha) (P90-RSK) (MAP kinase-activated protein kinase 1) (MAPK-activated protein kinase 1) (MAPKAP kinase 1) (MAPKAPK-1) Length = 733 Score = 35.4 bits (80), Expect = 0.15 Identities = 16/49 (32%), Positives = 27/49 (55%) Frame = -3 Query: 658 LEYSAPEFAMSGTYTVKSDVYSFGVVMLELLTGRKPLDRSRERSEQSLV 512 +EY APE ++ +D +S+GV+M E+LTG P + +L+ Sbjct: 226 VEYMAPEVVNRQGHSHSADWWSYGVLMFEMLTGSLPFQGKDRKETMTLI 274
>CDR2_SCHPO (P87050) Mitosis inducer protein kinase cdr2 (EC 2.7.11.1)| Length = 775 Score = 35.4 bits (80), Expect = 0.15 Identities = 17/43 (39%), Positives = 25/43 (58%), Gaps = 1/43 (2%) Frame = -3 Query: 652 YSAPEFAMSGTYT-VKSDVYSFGVVMLELLTGRKPLDRSRERS 527 Y++PE M +Y SD++S G++ LLTG+ P D RS Sbjct: 173 YASPEIIMGRSYDGCASDIWSCGIIFFALLTGKLPFDDDNIRS 215
>M3K2_ARATH (Q9FZ36) Mitogen-activated protein kinase kinase kinase 2 (EC| 2.7.11.25) (Arabidospsis NPK1-related protein kinase 2) Length = 651 Score = 35.0 bits (79), Expect = 0.20 Identities = 24/103 (23%), Positives = 45/103 (43%) Frame = -3 Query: 652 YSAPEFAMSGTYTVKSDVYSFGVVMLELLTGRKPLDRSRERSEQSLVGWATPQLHDIDAL 473 + APE + ++ +D++S G ++E++TG+ P W + Q +I A+ Sbjct: 239 WMAPEVILQTGHSFSADIWSVGCTVIEMVTGKAP--------------W-SQQYKEIAAI 283 Query: 472 AKMVDPAMDGMYPAKSLSRFADIIALSVQPEPEFRPPISEVVQ 344 + P S D + +Q EP RP SE+++ Sbjct: 284 FHIGTTKSHPPIPDNISSDANDFLLKCLQQEPNLRPTASELLK 326
>IGF1R_HUMAN (P08069) Insulin-like growth factor 1 receptor precursor (EC| 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD221 antigen) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 recepto Length = 1367 Score = 35.0 bits (79), Expect = 0.20 Identities = 26/112 (23%), Positives = 47/112 (41%) Frame = -3 Query: 658 LEYSAPEFAMSGTYTVKSDVYSFGVVMLELLTGRKPLDRSRERSEQSLVGWATPQLHDID 479 + + +PE G +T SDV+SFGVV+ E+ T +EQ G + Q+ Sbjct: 1176 VRWMSPESLKDGVFTTYSDVWSFGVVLWEIAT----------LAEQPYQGLSNEQVLRFV 1225 Query: 478 ALAKMVDPAMDGMYPAKSLSRFADIIALSVQPEPEFRPPISEVVQQLVRLMQ 323 ++D P +++ + Q P+ RP E++ + M+ Sbjct: 1226 MEGGLLDK------PDNCPDMLFELMRMCWQYNPKMRPSFLEIISSIKEEME 1271 Database: uniprot_sprot.fasta Posted date: May 25, 2006 5:36 PM Number of letters in database: 80,573,946 Number of sequences in database: 219,361 Lambda K H 0.318 0.135 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 98,583,799 Number of Sequences: 219361 Number of extensions: 2105123 Number of successful extensions: 6927 Number of sequences better than 10.0: 500 Number of HSP's better than 10.0 without gapping: 6597 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 6906 length of database: 80,573,946 effective HSP length: 108 effective length of database: 56,882,958 effective search space used: 6427774254 frameshift window, decay const: 50, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
