>UFC1_BOVIN (Q5E953) Ufm1-conjugating enzyme 1 (Ubiquitin-fold|
           modifier-conjugating enzyme 1)
          Length = 167

 Score =  183 bits (464), Expect(2) = 2e-46
 Identities = 77/119 (64%), Positives = 95/119 (79%)
 Frame = -2

Query: 542 NKAKDNDWFRISAANPEGTRWEGTCWYVHNLRRYEFPLQFDIPVAYPQVAPEIELPTLDG 363
           NK  DNDWFR+ + N EGTRW G CWY+H+L +YEF ++FDIP+ YP  APEI +P LDG
Sbjct: 46  NKNADNDWFRLES-NKEGTRWFGKCWYIHDLLKYEFDIEFDIPITYPTTAPEIAVPELDG 104

Query: 362 KTHKMYRGGKICLTVHFKPLWAKNCPRFGLAHALCLGLAPWLAAEVPILVDSGMVKHKD 186
           KT KMYRGGKICLT HFKPLWA+N P+FGLAH + LGL PWLA E+P L+  G+++HK+
Sbjct: 105 KTAKMYRGGKICLTDHFKPLWARNVPKFGLAHLMALGLGPWLAVEIPDLIQKGVIQHKE 163



 Score = 22.7 bits (47), Expect(2) = 2e-46
 Identities = 9/12 (75%), Positives = 11/12 (91%)
 Frame = -1

Query: 588 RLKEEYRALIAY 553
           RLKEEY++LI Y
Sbjct: 31  RLKEEYQSLIRY 42

>UFC1_HUMAN (Q9Y3C8) Ufm1-conjugating enzyme 1 (Ubiquitin-fold|
           modifier-conjugating enzyme 1)
          Length = 167

 Score =  182 bits (462), Expect(2) = 3e-46
 Identities = 77/119 (64%), Positives = 94/119 (78%)
 Frame = -2

Query: 542 NKAKDNDWFRISAANPEGTRWEGTCWYVHNLRRYEFPLQFDIPVAYPQVAPEIELPTLDG 363
           NK  DNDWFR+ + N EGTRW G CWY+H+L +YEF ++FDIP+ YP  APEI +P LDG
Sbjct: 46  NKNADNDWFRLES-NKEGTRWFGKCWYIHDLLKYEFDIEFDIPITYPTTAPEIAVPELDG 104

Query: 362 KTHKMYRGGKICLTVHFKPLWAKNCPRFGLAHALCLGLAPWLAAEVPILVDSGMVKHKD 186
           KT KMYRGGKICLT HFKPLWA+N P+FGLAH + LGL PWLA E+P L+  G++ HK+
Sbjct: 105 KTAKMYRGGKICLTDHFKPLWARNVPKFGLAHLMALGLGPWLAVEIPDLIQKGVIHHKE 163



 Score = 22.7 bits (47), Expect(2) = 3e-46
 Identities = 9/12 (75%), Positives = 11/12 (91%)
 Frame = -1

Query: 588 RLKEEYRALIAY 553
           RLKEEY++LI Y
Sbjct: 31  RLKEEYQSLIRY 42

>UFC1_MOUSE (Q9CR09) Ufm1-conjugating enzyme 1 (Ubiquitin-fold|
           modifier-conjugating enzyme 1)
          Length = 167

 Score =  181 bits (458), Expect(2) = 8e-46
 Identities = 76/119 (63%), Positives = 94/119 (78%)
 Frame = -2

Query: 542 NKAKDNDWFRISAANPEGTRWEGTCWYVHNLRRYEFPLQFDIPVAYPQVAPEIELPTLDG 363
           NK  DNDWFR+ + N EGTRW G CWY+H+  +YEF ++F+IP+ YP  APEI +P LDG
Sbjct: 46  NKNSDNDWFRLES-NKEGTRWFGKCWYIHDFLKYEFDIEFEIPITYPTTAPEIAVPELDG 104

Query: 362 KTHKMYRGGKICLTVHFKPLWAKNCPRFGLAHALCLGLAPWLAAEVPILVDSGMVKHKD 186
           KT KMYRGGKICLT HFKPLWA+N P+FGLAH + LGL PWLA EVP L+  G+++HK+
Sbjct: 105 KTAKMYRGGKICLTDHFKPLWARNVPKFGLAHLMALGLGPWLAVEVPDLIQKGVIQHKE 163



 Score = 22.7 bits (47), Expect(2) = 8e-46
 Identities = 9/12 (75%), Positives = 11/12 (91%)
 Frame = -1

Query: 588 RLKEEYRALIAY 553
           RLKEEY++LI Y
Sbjct: 31  RLKEEYQSLIRY 42

>UFC1_RAT (Q6BBI8) Ufm1-conjugating enzyme 1 (Ubiquitin-fold|
           modifier-conjugating enzyme 1)
          Length = 167

 Score =  180 bits (457), Expect(2) = 1e-45
 Identities = 76/119 (63%), Positives = 94/119 (78%)
 Frame = -2

Query: 542 NKAKDNDWFRISAANPEGTRWEGTCWYVHNLRRYEFPLQFDIPVAYPQVAPEIELPTLDG 363
           NK  DNDWFR+ + N EGTRW G CWY+H+  +YEF ++F+IP+ YP  APEI +P LDG
Sbjct: 46  NKNADNDWFRLES-NKEGTRWFGKCWYIHDFLKYEFDIEFEIPITYPTTAPEIAVPELDG 104

Query: 362 KTHKMYRGGKICLTVHFKPLWAKNCPRFGLAHALCLGLAPWLAAEVPILVDSGMVKHKD 186
           KT KMYRGGKICLT HFKPLWA+N P+FGLAH + LGL PWLA EVP L+  G+++HK+
Sbjct: 105 KTAKMYRGGKICLTDHFKPLWARNVPKFGLAHLMALGLGPWLAVEVPDLIQKGVIQHKE 163



 Score = 22.7 bits (47), Expect(2) = 1e-45
 Identities = 9/12 (75%), Positives = 11/12 (91%)
 Frame = -1

Query: 588 RLKEEYRALIAY 553
           RLKEEY++LI Y
Sbjct: 31  RLKEEYQSLIRY 42

>UFC1_CAEEL (Q03598) Probable Ufm1-conjugating enzyme (Ubiquitin-fold|
           modifier-conjugating enzyme)
          Length = 162

 Score =  170 bits (430), Expect(2) = 2e-42
 Identities = 71/118 (60%), Positives = 91/118 (77%)
 Frame = -2

Query: 542 NKAKDNDWFRISAANPEGTRWEGTCWYVHNLRRYEFPLQFDIPVAYPQVAPEIELPTLDG 363
           NK  D DWF++ + N  GT+W G CWY HN+ +YEF ++FDIP+ YP  APEI LP LDG
Sbjct: 45  NKDCDRDWFQLES-NERGTKWFGKCWYFHNMVKYEFDVEFDIPITYPVTAPEIALPELDG 103

Query: 362 KTHKMYRGGKICLTVHFKPLWAKNCPRFGLAHALCLGLAPWLAAEVPILVDSGMVKHK 189
           KT KMYRGGKICL+ HFKPLWA+N P+FG+AHA  LGL PW+A E+P L++ G+++ K
Sbjct: 104 KTAKMYRGGKICLSEHFKPLWARNTPKFGIAHAFALGLGPWMAVEIPDLIEKGLIQPK 161



 Score = 21.9 bits (45), Expect(2) = 2e-42
 Identities = 9/11 (81%), Positives = 10/11 (90%)
 Frame = -1

Query: 588 RLKEEYRALIA 556
           RLKEEY A+IA
Sbjct: 30  RLKEEYEAIIA 40

>FUSB_BURCE (P24127) Fusaric acid resistance protein fusB|
          Length = 142

 Score = 32.0 bits (71), Expect = 1.4
 Identities = 16/40 (40%), Positives = 19/40 (47%)
 Frame = -3

Query: 334 RSASPCTSSRSGPRTARGSGSRTRCASASRRGSPRRCPSW 215
           R A+PC+   S    AR SGS  R  S+    S R C  W
Sbjct: 71  RKAAPCSRKASTGSPARSSGSSRRSRSSGCSRSSRSCSCW 110

>GCP2_CAEBR (Q5WN23) Glutamate carboxypeptidase 2 homolog (EC 3.4.17.21)|
           (Glutamate carboxypeptidase II homolog)
          Length = 770

 Score = 31.2 bits (69), Expect = 2.3
 Identities = 16/36 (44%), Positives = 25/36 (69%)
 Frame = -1

Query: 114 QYVFFVVADSDSYSVMIVRGIEGLKIHSVXTNKSQQ 7
           ++V F V+DSDSYS  ++ GI+   IHS  T+ S++
Sbjct: 709 RHVLFSVSDSDSYSNSLMAGIQN-AIHSYETSPSKK 743

>UBC9_YEAST (P50623) Ubiquitin-conjugating enzyme E2-18 kDa (EC 6.3.2.19)|
           (Ubiquitin-protein ligase) (Ubiquitin carrier protein)
          Length = 157

 Score = 30.8 bits (68), Expect = 3.0
 Identities = 18/60 (30%), Positives = 27/60 (45%), Gaps = 1/60 (1%)
 Frame = -2

Query: 494 EGTRWEGTCWYVHNLRRYEFPLQFDIPVAYPQVAPEIELPTLDGKTH-KMYRGGKICLTV 318
           EGT W G            +P+  + P  YP   P+++ P   G  H  +Y  G ICL++
Sbjct: 49  EGTNWAGGV----------YPITVEYPNEYPSKPPKVKFPA--GFYHPNVYPSGTICLSI 96

>DESP_HUMAN (P15924) Desmoplakin (DP) (250/210 kDa paraneoplastic pemphigus|
            antigen)
          Length = 2871

 Score = 30.4 bits (67), Expect = 4.0
 Identities = 16/30 (53%), Positives = 18/30 (60%)
 Frame = -3

Query: 325  SPCTSSRSGPRTARGSGSRTRCASASRRGS 236
            S    SRSG R+   SGSR+   S SRRGS
Sbjct: 2820 SSAPGSRSGSRSGSRSGSRSGSRSGSRRGS 2849

>E2AK4_MOUSE (Q9QZ05) Eukaryotic translation initiation factor 2-alpha kinase 4|
           (EC 2.7.11.1) (GCN2-like protein) (mGCN2)
          Length = 1648

 Score = 30.4 bits (67), Expect = 4.0
 Identities = 21/58 (36%), Positives = 25/58 (43%), Gaps = 3/58 (5%)
 Frame = -2

Query: 431 LQFDIPVAYPQVAPEIELPTLDGKTHKMYRGGKICLTVHFKPLWAKNCPR---FGLAH 267
           LQ   P  YP V PEIEL    G +++        L  H + L  K C     F LAH
Sbjct: 75  LQVKCPPTYPDVVPEIELKNAKGLSNESVN----LLKSHLEELAKKQCGEVMIFELAH 128

>CHD6_HUMAN (Q8TD26) Chromodomain-helicase-DNA-binding protein 6 (EC 3.6.1.-)|
           (ATP-dependent helicase CHD6) (CHD-6) (Radiation-induced
           gene B protein)
          Length = 2715

 Score = 30.0 bits (66), Expect = 5.2
 Identities = 16/42 (38%), Positives = 23/42 (54%), Gaps = 4/42 (9%)
 Frame = +3

Query: 213 DQDGHLRGEPRREAEAQRVREP----EPRAVLGPERLEVHGE 326
           DQ+G  +G   RE + +R REP    EPR    P++ + H E
Sbjct: 103 DQEGAAKGSKDREPKPKRKREPKEPKEPRKAEEPKKAKEHKE 144

>FILA_HUMAN (P20930) Filaggrin|
          Length = 4061

 Score = 30.0 bits (66), Expect = 5.2
 Identities = 16/47 (34%), Positives = 25/47 (53%)
 Frame = -3

Query: 346  TAGGRSASPCTSSRSGPRTARGSGSRTRCASASRRGSPRRCPSWSIR 206
            ++GG++AS    +RS P    GS  +    S+   G PRR  S ++R
Sbjct: 1013 SSGGQAASSHEQARSSPGERHGSRHQQSADSSRHSGIPRRQASSAVR 1059

>DNAJ_BACSK (Q5WHG0) Chaperone protein dnaJ|
          Length = 372

 Score = 30.0 bits (66), Expect = 5.2
 Identities = 17/47 (36%), Positives = 27/47 (57%), Gaps = 8/47 (17%)
 Frame = -2

Query: 476 GTCWYVHNLRRYEF------PLQFDIPVAYPQVA--PEIELPTLDGK 360
           G  + V  ++ +EF       +  ++P+ +PQVA   EIE+PTL GK
Sbjct: 244 GDLYVVFQVKPHEFFERDGEDIYCEVPLTFPQVALGDEIEVPTLTGK 290

>CWC22_YARLI (Q6C8C5) Pre-mRNA-splicing factor CWC22|
          Length = 954

 Score = 30.0 bits (66), Expect = 5.2
 Identities = 17/36 (47%), Positives = 20/36 (55%)
 Frame = -3

Query: 334 RSASPCTSSRSGPRTARGSGSRTRCASASRRGSPRR 227
           RS +    SRS PR+   S SR+R  S  R GSP R
Sbjct: 812 RSLTRSPGSRSRPRSRPRSRSRSRSLSRDRTGSPPR 847

>UBE2N_MACFA (Q4R4I1) Ubiquitin-conjugating enzyme E2 N (EC 6.3.2.19)|
           (Ubiquitin-protein ligase N) (Ubiquitin carrier protein
           N)
          Length = 152

 Score = 29.3 bits (64), Expect = 8.8
 Identities = 21/80 (26%), Positives = 35/80 (43%), Gaps = 5/80 (6%)
 Frame = -2

Query: 521 WFRISAANPEGTRWEGTCWYVHNLRRYEFPLQFDIPVAYPQVAPEIELPTLDGKTHKMY- 345
           +F +  A P+ + +EG            F L+  +P  YP  AP++   T      K+Y 
Sbjct: 34  YFHVVIAGPQDSPFEGGT----------FKLELFLPEEYPMAAPKVRFMT------KIYH 77

Query: 344 ----RGGKICLTVHFKPLWA 297
               + G+ICL +  K  W+
Sbjct: 78  PNVDKSGRICLDI-LKDKWS 96


  Database: uniprot_sprot.fasta
    Posted date:  May 25, 2006  5:36 PM
  Number of letters in database: 80,573,946
  Number of sequences in database:  219,361
  
Lambda     K      H
   0.318    0.135    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 62,322,780
Number of Sequences: 219361
Number of extensions: 1086357
Number of successful extensions: 4441
Number of sequences better than 10.0: 15
Number of HSP's better than 10.0 without gapping: 4161
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4417
length of database: 80,573,946
effective HSP length: 106
effective length of database: 57,321,680
effective search space used: 5101629520
frameshift window, decay const: 50,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)