>SAP_CHICK (O13035) Proactivator polypeptide precursor [Contains: Saposin A;|
Saposin B; Saposin C; Saposin D]
Length = 518
Score = 45.4 bits (106), Expect = 1e-04
Identities = 31/123 (25%), Positives = 58/123 (47%), Gaps = 3/123 (2%)
Frame = -2
Query: 604 CRDNALLSGVRSESTCVFCHHLMDEVLSKLKDPDAEFEIIQILLKECKKI--EGHEQQCK 431
C+ N + C C L+ V LKD E EI L K C+ + +G +CK
Sbjct: 49 CQQNVWSKPAVNSIPCDLCKELVTVVGKVLKDNGTEDEIRSYLEKRCEFLPDQGLASECK 108
Query: 430 RLVLQYIPLIL-VNGEKFLEKNDICTIVQACDAGKKTVLGSFSEEGLLRDE*RQKDYTEP 254
+V Y+P+I+ + E+F + +C+ + C + +K + ++ L ++ + D++E
Sbjct: 109 EIVDSYLPVIMDMIKEEFDKPEVVCSALSLCQSLQKHLAAMKLQKQLQSNKIPELDFSEL 168
Query: 253 RKP 245
P
Sbjct: 169 TSP 171
Score = 37.0 bits (84), Expect = 0.052
Identities = 23/83 (27%), Positives = 39/83 (46%), Gaps = 1/83 (1%)
Frame = -2
Query: 559 CVFCHHLMDEVLSKLKDPDAEFEIIQILLKECKKI-EGHEQQCKRLVLQYIPLILVNGEK 383
C C ++ +L+ EI +L K C + E QC + V QY P+++ +
Sbjct: 403 CDICKMIVAYADKELEKNATTTEIEALLEKVCHFLPESVSDQCVQFVEQYEPVVVQLLAE 462
Query: 382 FLEKNDICTIVQACDAGKKTVLG 314
++ +CT + C A KK +LG
Sbjct: 463 MMDPTFVCTKLGVCGAAKKPLLG 485
>SAP_HUMAN (P07602) Proactivator polypeptide precursor [Contains: Saposin A|
(Protein A); Saposin B-Val; Saposin B (Sphingolipid
activator protein 1) (SAP-1) (Cerebroside sulfate
activator) (CSAct) (Dispersin) (Sulfatide/GM1
activator); Saposin C (Co-beta-
Length = 524
Score = 43.1 bits (100), Expect = 7e-04
Identities = 27/120 (22%), Positives = 56/120 (46%), Gaps = 7/120 (5%)
Frame = -2
Query: 649 IAEIKPEEFCKRNGLCRDNAL------LSGVRSESTCVFCHHLMDEVLSKLKDPDAEFEI 488
+ E+ PE C LC L ++ + C C L+ + L+ + EI
Sbjct: 373 LEEVSPELVCSMLHLCSGTRLPALTVHVTQPKDGGFCEVCKKLVGYLDRNLEKNSTKQEI 432
Query: 487 IQILLKECKKI-EGHEQQCKRLVLQYIPLILVNGEKFLEKNDICTIVQACDAGKKTVLGS 311
+ L K C + + +++QC + V +Y P+++ + ++ + +C + AC + K +LG+
Sbjct: 433 LAALEKGCSFLPDPYQKQCDQFVAEYEPVLIEILVEVMDPSFVCLKIGACPSAHKPLLGT 492
Score = 36.2 bits (82), Expect = 0.089
Identities = 28/109 (25%), Positives = 49/109 (44%), Gaps = 4/109 (3%)
Frame = -2
Query: 559 CVFCHHLMDEVLSKLKDPDAEFEIIQILLKECKKI--EGHEQQCKRLVLQYIPLIL--VN 392
C C ++ LKD E EI+ L K C + CK +V Y+P+IL +
Sbjct: 63 CDICKDVVTAAGDMLKDNATEEEILVYLEKTCDWLPKPNMSASCKEIVDSYLPVILDIIK 122
Query: 391 GEKFLEKNDICTIVQACDAGKKTVLGSFSEEGLLRDE*RQKDYTEPRKP 245
GE ++C+ + C++ +K + ++ L ++ + D TE P
Sbjct: 123 GE-MSRPGEVCSALNLCESLQKHLAELNHQKQLESNKIPELDMTEVVAP 170
>SAP_BOVIN (P26779) Proactivator polypeptide precursor [Contains: Saposin A|
(Protein A); Saposin B (Sphingolipid activator protein
1) (SAP-1) (Cerebroside sulfate activator) (CSAct)
(Dispersin) (Sulfatide/GM1 activator); Saposin C
(Co-beta-glucosidase) (A
Length = 525
Score = 41.2 bits (95), Expect = 0.003
Identities = 27/118 (22%), Positives = 52/118 (44%), Gaps = 7/118 (5%)
Frame = -2
Query: 643 EIKPEEFCKRNGLCRDNALLSGV------RSESTCVFCHHLMDEVLSKLKDPDAEFEIIQ 482
E PE C LC L + + C C L+ + L+ + +I+
Sbjct: 376 EASPELVCSMLHLCSSRGLPAATVRVMPRKDGGFCEVCKKLVGYLDRNLEKNSTKEQILA 435
Query: 481 ILLKECKKI-EGHEQQCKRLVLQYIPLILVNGEKFLEKNDICTIVQACDAGKKTVLGS 311
L K C + + + +QC + V +Y P+++ + ++ + +C + AC A K +LG+
Sbjct: 436 ALEKGCSFLPDQYRKQCDQFVTEYEPVLIEILVEVMDPSFVCLKIGACPAAHKPLLGA 493
Score = 33.5 bits (75), Expect = 0.58
Identities = 21/82 (25%), Positives = 39/82 (47%), Gaps = 4/82 (4%)
Frame = -2
Query: 559 CVFCHHLMDEVLSKLKDPDAEFEIIQILLKECKKIE--GHEQQCKRLVLQYIPLIL--VN 392
C C ++ + LKD E EI+ L + C + CK +V Y+P+IL +
Sbjct: 63 CDICKDVITAAGNLLKDNATEQEILMYLERTCDWLPKPNMSASCKEIVDSYLPVILDMIK 122
Query: 391 GEKFLEKNDICTIVQACDAGKK 326
G+ ++C+ + C++ +K
Sbjct: 123 GQ-MSHPGEVCSALNLCESLQK 143
>SAP_RAT (P10960) Sulfated glycoprotein 1 precursor (SGP-1) (Prosaposin)|
Length = 554
Score = 38.1 bits (87), Expect = 0.023
Identities = 21/84 (25%), Positives = 43/84 (51%), Gaps = 1/84 (1%)
Frame = -2
Query: 559 CVFCHHLMDEVLSKLKDPDAEFEIIQILLKECKKI-EGHEQQCKRLVLQYIPLILVNGEK 383
C C L+ + L+ + EI+ L K C + + +++QC V +Y PL+L +
Sbjct: 439 CEVCKKLVIYLEHNLEKNSTKEEILAALEKGCSFLPDPYQKQCDEFVAEYEPLLLEILVE 498
Query: 382 FLEKNDICTIVQACDAGKKTVLGS 311
++ + +C+ + C + K +LG+
Sbjct: 499 VMDPSFVCSKIGVCPSAYKLLLGT 522
Score = 38.1 bits (87), Expect = 0.023
Identities = 27/107 (25%), Positives = 44/107 (41%), Gaps = 4/107 (3%)
Frame = -2
Query: 643 EIKPEEFCKRNGLCRDNALLSGVRSESTCVFCHHLMDEVLSKLKDPDAEFEIIQILLKEC 464
++K C+ C+ C C ++ E + LKD E EI+ L K C
Sbjct: 35 DVKTAVDCRAVKHCQQMVWSKPTAKSLPCDICKTVVTEAGNLLKDNATEEEILHYLEKTC 94
Query: 463 KKIEGH--EQQCKRLVLQYIPLIL--VNGEKFLEKNDICTIVQACDA 335
I CK +V Y+P+IL + GE ++C+ + C +
Sbjct: 95 AWIHDSSLSASCKEVVDSYLPVILDMIKGE-MSNPGEVCSALNLCQS 140
>SAP_MOUSE (Q61207) Sulfated glycoprotein 1 precursor (SGP-1) (Prosaposin)|
Length = 557
Score = 36.6 bits (83), Expect = 0.068
Identities = 21/84 (25%), Positives = 42/84 (50%), Gaps = 1/84 (1%)
Frame = -2
Query: 559 CVFCHHLMDEVLSKLKDPDAEFEIIQILLKECKKI-EGHEQQCKRLVLQYIPLILVNGEK 383
C C L+ + L+ + EI+ L K C + + +++QC V +Y PL+L +
Sbjct: 442 CEVCKKLVLYLEHNLEKNSTKEEILAALEKGCSFLPDPYQKQCDDFVAEYEPLLLEILVE 501
Query: 382 FLEKNDICTIVQACDAGKKTVLGS 311
++ +C+ + C + K +LG+
Sbjct: 502 VMDPGFVCSKIGVCPSAYKLLLGT 525
Score = 36.6 bits (83), Expect = 0.068
Identities = 23/79 (29%), Positives = 38/79 (48%), Gaps = 4/79 (5%)
Frame = -2
Query: 559 CVFCHHLMDEVLSKLKDPDAEFEIIQILLKECKKIEGH--EQQCKRLVLQYIPLIL--VN 392
C C ++ E + LKD + EI+ L K C+ I CK +V Y+P+IL +
Sbjct: 63 CDICKTVVTEAGNLLKDNATQEEILHYLEKTCEWIHDSSLSASCKEVVDSYLPVILDMIK 122
Query: 391 GEKFLEKNDICTIVQACDA 335
GE ++C+ + C +
Sbjct: 123 GE-MSNPGEVCSALNLCQS 140
>GLRX1_YEAST (P25373) Glutaredoxin-1 (Glutathione-dependent oxidoreductase 1)|
Length = 110
Score = 29.6 bits (65), Expect = 8.3
Identities = 21/75 (28%), Positives = 40/75 (53%), Gaps = 3/75 (4%)
Frame = -2
Query: 577 VRSESTCVFCHHLMDEVLSKLKDPDAEFEIIQIL-LKECKKIEG--HEQQCKRLVLQYIP 407
V S++ C +CH ++ + KLK P ++ ++Q+ +KE I+ +E +R V P
Sbjct: 21 VASKTYCPYCHAALNTLFEKLKVPRSKVLVLQLNDMKEGADIQAALYEINGQRTV----P 76
Query: 406 LILVNGEKFLEKNDI 362
I +NG+ +D+
Sbjct: 77 NIYINGKHIGGNDDL 91
Database: uniprot_sprot.fasta
Posted date: May 25, 2006 5:36 PM
Number of letters in database: 80,573,946
Number of sequences in database: 219,361
Lambda K H
0.318 0.135 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 93,578,660
Number of Sequences: 219361
Number of extensions: 1910053
Number of successful extensions: 5436
Number of sequences better than 10.0: 13
Number of HSP's better than 10.0 without gapping: 5258
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5432
length of database: 80,573,946
effective HSP length: 108
effective length of database: 56,882,958
effective search space used: 6314008338
frameshift window, decay const: 50, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)