>WBS22_MOUSE (Q9CY21) Putative methyltransferase WBSCR22 (EC 2.1.1.-)|
           (Williams-Beuren syndrome chromosome region 22 protein
           homolog)
          Length = 281

 Score =  121 bits (303), Expect = 2e-27
 Identities = 71/155 (45%), Positives = 95/155 (61%)
 Frame = -2

Query: 663 LKAFFGSLYRCLARGARAVLQFYADNVKQTEMLVSFAMKAGFAGGVVIDWPHSSKAKKSY 484
           L  FF SLY  L RGARAVLQ Y +N +Q E++ + A +AGF GGVV+D+P+S+KAKK Y
Sbjct: 142 LYCFFSSLYSALVRGARAVLQLYPENSEQLELITTQATRAGFTGGVVVDFPNSAKAKKFY 201

Query: 483 LVLTCGTSSVTSLPKGKGENGEMCXXXXXXXXXXXXXDQTVGTYGRNRSNKRQKVNKKNG 304
           L L  G S  TSLPKG  E+ +                +++ T  R    K ++   K  
Sbjct: 202 LCLFSGPS--TSLPKGLTESQD-----------ADQASESMFTSERAPHKKARRDLVKKS 248

Query: 303 RGKDWLLRKKEQMRKRGREVPADTKYTGRKRKTRF 199
           R  +W+L KKE+ R++G+EV  DT+YTGRKRK RF
Sbjct: 249 R--EWVLEKKERRRRQGKEVRPDTQYTGRKRKPRF 281

>WBS22_HUMAN (O43709) Putative methyltransferase WBSCR22 (EC 2.1.1.-)|
           (Williams-Beuren syndrome chromosome region 22 protein)
          Length = 281

 Score =  115 bits (287), Expect = 2e-25
 Identities = 70/157 (44%), Positives = 96/157 (61%), Gaps = 2/157 (1%)
 Frame = -2

Query: 663 LKAFFGSLYRCLARGARAVLQFYADNVKQTEMLVSFAMKAGFAGGVVIDWPHSSKAKKSY 484
           L  FF SL+  L RG+RAVLQ Y +N +Q E++ + A KAGF+GG+V+D+P+S+KAKK Y
Sbjct: 142 LYCFFASLFSVLVRGSRAVLQLYPENSEQLELITTQATKAGFSGGMVVDYPNSAKAKKFY 201

Query: 483 LVLTCGTSSVTSLPKGKGENGEMCXXXXXXXXXXXXXDQTVGTYGR--NRSNKRQKVNKK 310
           L L  G S  T +P+G  EN +                ++V T  R   R ++R  V K 
Sbjct: 202 LCLFSGPS--TFIPEGLSENQD-----------EVEPRESVFTNERFPLRMSRRGMVRK- 247

Query: 309 NGRGKDWLLRKKEQMRKRGREVPADTKYTGRKRKTRF 199
               + W+L KKE+ R++GREV  DT+YTGRKRK RF
Sbjct: 248 ---SRAWVLEKKERHRRQGREVRPDTQYTGRKRKPRF 281

>YAU6_SCHPO (Q10162) Hypothetical methyltransferase C26A3.06 in chromosome I|
          Length = 268

 Score = 96.3 bits (238), Expect = 7e-20
 Identities = 56/156 (35%), Positives = 82/156 (52%), Gaps = 1/156 (0%)
 Frame = -2

Query: 663 LKAFFGSLYRCLARGARAVLQFYADNVKQTEMLVSFAMKAGFAGGVVIDWPHSSKAKKSY 484
           L  FF +LY  + RG RAV+Q+Y +  K  +M++  A KAGFAGG+V+D P S + KK Y
Sbjct: 137 LNRFFQTLYISMKRGGRAVMQYYPETEKSQQMIMDTARKAGFAGGIVVDHPESKRQKKYY 196

Query: 483 LVLTCGTSSVTSLPKGKGENGEMCXXXXXXXXXXXXXDQTVGTYGRNRSNKRQKVNKKNG 304
           LVL  G +    +                          T+   G N   ++ K  K++ 
Sbjct: 197 LVLQAGGTRTLDI-----------------------SSMTLDQEGTNAKQRKLK-KKQDM 232

Query: 303 RGKDWLLRKKEQMRKRGR-EVPADTKYTGRKRKTRF 199
             +++++ KKE  RKRGR  VP D+KY+GR+RK  F
Sbjct: 233 STREYIIHKKELNRKRGRLHVPKDSKYSGRRRKAAF 268

>BUD23_YEAST (P25627) Putative methyltransferase BUD23 (EC 2.1.1.-) (Bud site|
           selection protein 23)
          Length = 275

 Score = 92.4 bits (228), Expect = 1e-18
 Identities = 57/155 (36%), Positives = 83/155 (53%)
 Frame = -2

Query: 663 LKAFFGSLYRCLARGARAVLQFYADNVKQTEMLVSFAMKAGFAGGVVIDWPHSSKAKKSY 484
           L  FF +LY  L +G + V QFY  N  Q + ++  A  AGF+GG+V+D P S K KK Y
Sbjct: 137 LMRFFNTLYAALKKGGKFVAQFYPKNDDQVDDILQSAKVAGFSGGLVVDDPESKKNKKYY 196

Query: 483 LVLTCGTSSVTSLPKGKGENGEMCXXXXXXXXXXXXXDQTVGTYGRNRSNKRQKVNKKNG 304
           LVL+ G       P+G+ +                  ++ V    + +  +R K  K   
Sbjct: 197 LVLSSGAP-----PQGEEQ---------VNLDGVTMDEENVNL--KKQLRQRLKGGKDKE 240

Query: 303 RGKDWLLRKKEQMRKRGREVPADTKYTGRKRKTRF 199
             K ++LRKKE M++RGR+V  D+K+TGRKR+ RF
Sbjct: 241 SAKSFILRKKELMKRRGRKVAKDSKFTGRKRRHRF 275

>CP46A_HUMAN (Q9Y6A2) Cytochrome p450 46A1 (EC 1.14.13.98) (Cholesterol|
           24-hydroxylase) (CH24H)
          Length = 500

 Score = 31.2 bits (69), Expect = 2.9
 Identities = 13/22 (59%), Positives = 18/22 (81%)
 Frame = -2

Query: 300 GKDWLLRKKEQMRKRGREVPAD 235
           G+DW+ R++E + KRG EVPAD
Sbjct: 254 GRDWVQRRREAL-KRGEEVPAD 274

>CP46A_MOUSE (Q9WVK8) Cytochrome p450 46A1 (EC 1.14.13.98) (Cholesterol|
           24-hydroxylase) (CH24H)
          Length = 500

 Score = 30.4 bits (67), Expect = 4.9
 Identities = 13/32 (40%), Positives = 21/32 (65%)
 Frame = -2

Query: 330 RQKVNKKNGRGKDWLLRKKEQMRKRGREVPAD 235
           R+ +      GKDW+ R++E + KRG ++PAD
Sbjct: 244 RESIRLLRQVGKDWVQRRREAL-KRGEDMPAD 274


  Database: uniprot_sprot.fasta
    Posted date:  May 25, 2006  5:36 PM
  Number of letters in database: 80,573,946
  Number of sequences in database:  219,361
  
Lambda     K      H
   0.318    0.135    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 80,728,156
Number of Sequences: 219361
Number of extensions: 1390150
Number of successful extensions: 3672
Number of sequences better than 10.0: 6
Number of HSP's better than 10.0 without gapping: 3574
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3660
length of database: 80,573,946
effective HSP length: 108
effective length of database: 56,882,958
effective search space used: 6370891296
frameshift window, decay const: 50,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)