>RIFK_MOUSE (Q8CFV9) Riboflavin kinase (EC 2.7.1.26) (ATP:riboflavin|
           5'-phosphotransferase) (Flavokinase) (KOI-4)
          Length = 155

 Score =  152 bits (383), Expect = 1e-36
 Identities = 70/139 (50%), Positives = 97/139 (69%)
 Frame = -3

Query: 685 FIGGPVIKGFGRGSKVLGIPTANLAAENFSDILSEHTSGVYFGWAGLSKRGIYKMVMSIG 506
           F  G V++GFGRGSK LGIPTAN   +   ++ ++ ++G+Y+GWA +    ++KMV+SIG
Sbjct: 7   FCRGQVVRGFGRGSKQLGIPTANFPEQVVDNLPADVSTGIYYGWASVGSGDVHKMVVSIG 66

Query: 505 WNPYFDNTEKTIEPWLLHGFDEDFYGEELRLVIVGYIRPEANFPSLESLIERIHEDGRIA 326
           WNPY+ N +K++E  ++H F EDFYGE L + IVGY+RPE NF SLESLI  I  D   A
Sbjct: 67  WNPYYKNVKKSMETHIIHTFKEDFYGEILNVAIVGYLRPEKNFDSLESLISAIQGDIEEA 126

Query: 325 ENALDLPEYAKYKDSPYLR 269
           +  LDLPE+ K KD  + +
Sbjct: 127 KKQLDLPEHLKLKDDNFFQ 145

>RIFK_HUMAN (Q969G6) Riboflavin kinase (EC 2.7.1.26) (ATP:riboflavin|
           5'-phosphotransferase) (Flavokinase)
          Length = 162

 Score =  150 bits (380), Expect = 3e-36
 Identities = 69/139 (49%), Positives = 98/139 (70%)
 Frame = -3

Query: 685 FIGGPVIKGFGRGSKVLGIPTANLAAENFSDILSEHTSGVYFGWAGLSKRGIYKMVMSIG 506
           F  G V++GFGRGSK LGIPTAN   +   ++ ++ ++G+Y+GWA +    ++KMV+SIG
Sbjct: 14  FCRGQVVRGFGRGSKQLGIPTANFPEQVVDNLPADISTGIYYGWASVGSGDVHKMVVSIG 73

Query: 505 WNPYFDNTEKTIEPWLLHGFDEDFYGEELRLVIVGYIRPEANFPSLESLIERIHEDGRIA 326
           WNPY+ NT+K++E  ++H F EDFYGE L + IVGY+RPE NF SLESLI  I  D   A
Sbjct: 74  WNPYYKNTKKSMETHIMHTFKEDFYGEILNVAIVGYLRPEKNFDSLESLISAIQGDIEEA 133

Query: 325 ENALDLPEYAKYKDSPYLR 269
           +  L+LPE+ K K+  + +
Sbjct: 134 KKRLELPEHLKIKEDNFFQ 152

>RIFK_SCHPO (O74866) Riboflavin kinase (EC 2.7.1.26) (ATP:riboflavin|
           5'-phosphotransferase) (Flavokinase)
          Length = 163

 Score =  144 bits (364), Expect = 2e-34
 Identities = 67/136 (49%), Positives = 95/136 (69%)
 Frame = -3

Query: 676 GPVIKGFGRGSKVLGIPTANLAAENFSDILSEHTSGVYFGWAGLSKRGIYKMVMSIGWNP 497
           G V+ GFGRGSK LGIPTAN++ +   ++L    SGVYFG+A + KR ++ MVMS+GWNP
Sbjct: 28  GKVVHGFGRGSKELGIPTANISEDAIQELLRYRDSGVYFGYAMVQKR-VFPMVMSVGWNP 86

Query: 496 YFDNTEKTIEPWLLHGFDEDFYGEELRLVIVGYIRPEANFPSLESLIERIHEDGRIAENA 317
           Y+ N  ++ E  L+    EDFY E +R++++GYIRPE N+  L+ LIE IH D R+A N+
Sbjct: 87  YYKNKLRSAEVHLIERQGEDFYEEIMRVIVLGYIRPELNYAGLDKLIEDIHTDIRVALNS 146

Query: 316 LDLPEYAKYKDSPYLR 269
           +D P Y+ YK  P+ +
Sbjct: 147 MDRPSYSSYKKDPFFK 162

>RIFK_DROME (O76206) Putative riboflavin kinase (EC 2.7.1.26) (ATP:riboflavin|
           5'-phosphotransferase) (Flavokinase)
          Length = 153

 Score =  142 bits (359), Expect = 7e-34
 Identities = 67/142 (47%), Positives = 94/142 (66%)
 Frame = -3

Query: 685 FIGGPVIKGFGRGSKVLGIPTANLAAENFSDILSEHTSGVYFGWAGLSKRGIYKMVMSIG 506
           F GG +++GFGRGSK LGIPTAN   E    +     +G Y+GWA +    ++KMV+SIG
Sbjct: 8   FAGGEIVRGFGRGSKELGIPTANFPLEVVKSLPESLPTGAYYGWANVDNGPVHKMVLSIG 67

Query: 505 WNPYFDNTEKTIEPWLLHGFDEDFYGEELRLVIVGYIRPEANFPSLESLIERIHEDGRIA 326
           WNP+++N EK++E  +LH F+ D YG+ L++ IVGY+RPE +F SLESLI  I  D   A
Sbjct: 68  WNPFYNNKEKSVETHMLHDFNCDLYGQTLKICIVGYLRPERSFDSLESLIAAIRGDIEQA 127

Query: 325 ENALDLPEYAKYKDSPYLRNPL 260
           +  LD  + AK K++P+    L
Sbjct: 128 KAFLDEADKAKLKEAPFFTEKL 149

>RIFK_YEAST (Q03778) Riboflavin kinase precursor (EC 2.7.1.26) (Flavin|
           mononucleotide kinase 1)
          Length = 218

 Score = 94.4 bits (233), Expect = 3e-19
 Identities = 54/159 (33%), Positives = 80/159 (50%), Gaps = 31/159 (19%)
 Frame = -3

Query: 670 VIKGFGRGSKVLGIPTANLAAENFSDILSEHTSGVYFGWAGLSK---------------- 539
           ++ GFGRGS  LGIPTAN+        +++   GVYFG+A +                  
Sbjct: 57  IVCGFGRGSAELGIPTANVPINQLPKGINDLDLGVYFGFAHIKTVDGQELSVETRRDGRT 116

Query: 538 ---------------RGIYKMVMSIGWNPYFDNTEKTIEPWLLHGFDEDFYGEELRLVIV 404
                            +  MV+S+G NP++ N  KT+E  ++H F  DFYG  ++  I+
Sbjct: 117 VVYNYGQYLSEANDDLSVLPMVLSVGKNPFYGNDFKTMELHIIHDFKNDFYGARVKFNIL 176

Query: 403 GYIRPEANFPSLESLIERIHEDGRIAENALDLPEYAKYK 287
           G+IRPE N+ + E+LIE I+ D R A+  L  P Y  +K
Sbjct: 177 GHIRPELNYTTKEALIEDINIDIRTAQTVLATPPYQVFK 215

>RIBF_CORAM (Q59263) Riboflavin biosynthesis protein ribF [Includes: Riboflavin|
           kinase (EC 2.7.1.26) (Flavokinase); FMN
           adenylyltransferase (EC 2.7.7.2) (FAD pyrophosphorylase)
           (FAD synthetase)]
          Length = 338

 Score = 75.5 bits (184), Expect = 1e-13
 Identities = 41/127 (32%), Positives = 68/127 (53%), Gaps = 11/127 (8%)
 Frame = -3

Query: 685 FIGGPVIKGFGRGSKVLGIPTANLAAENFSDILSEHTSGVYFGW-----------AGLSK 539
           ++ GPV++G GRG K LG PTAN   + F D ++    GVY GW             +  
Sbjct: 188 YVTGPVVRGAGRGGKELGFPTAN---QYFHDTVALPADGVYAGWLTILPTEAPVSGNMEP 244

Query: 538 RGIYKMVMSIGWNPYFDNTEKTIEPWLLHGFDEDFYGEELRLVIVGYIRPEANFPSLESL 359
              Y   +S+G NP F + ++++E ++L   D D YG ++++  V ++R    F S+E L
Sbjct: 245 EVAYAAAISVGTNPTFGDEQRSVESFVLDR-DADLYGHDVKVEFVDHVRAMEKFDSVEQL 303

Query: 358 IERIHED 338
           +E + +D
Sbjct: 304 LEVMAKD 310

>RIBF_SYNY3 (P73651) Riboflavin biosynthesis protein ribF [Includes: Riboflavin|
           kinase (EC 2.7.1.26) (Flavokinase); FMN
           adenylyltransferase (EC 2.7.7.2) (FAD pyrophosphorylase)
           (FAD synthetase)]
          Length = 284

 Score = 58.5 bits (140), Expect = 2e-08
 Identities = 44/124 (35%), Positives = 64/124 (51%), Gaps = 1/124 (0%)
 Frame = -3

Query: 676 GPVIKGFGRGSKVLGIPTANLAAENFSDILSEHTSGVYFGWAGLSKRGI-YKMVMSIGWN 500
           G V++G   G K LG PTANL     +D L     GVY GW  L+   +    V+++G  
Sbjct: 161 GTVVQGQQLGRK-LGFPTANLCLP--ADKLWPKY-GVYAGWVNLNALDVPIPAVINLGDR 216

Query: 499 PYFDNTEKTIEPWLLHGFDEDFYGEELRLVIVGYIRPEANFPSLESLIERIHEDGRIAEN 320
           P  +  E + E  LL  +  D YG+ L + +  Y+RPE  F  L+ L  +I +D + AE 
Sbjct: 217 PTVNGQEPSAEVHLLQ-WSGDLYGQGLEVALTHYLRPETKFAGLDQLKNQIAQDCQQAEK 275

Query: 319 ALDL 308
            L+L
Sbjct: 276 LLNL 279

>RIBR_BACSU (P94465) Regulatory protein ribR|
          Length = 230

 Score = 57.0 bits (136), Expect = 5e-08
 Identities = 46/116 (39%), Positives = 61/116 (52%), Gaps = 1/116 (0%)
 Frame = -3

Query: 682 IGGPVIKGFGRGSKVLGIPTANLAAENFSDILSEHTSGVYFGWAGLSKRGIYKMVMSIGW 503
           I G V+KG   G K LG PTAN+ A+     +    +GVY G         +  VM+IG 
Sbjct: 4   IAGTVVKGKQLGRK-LGFPTANVDAK-----IHGLRNGVY-GVLATVNHQFHLGVMNIGV 56

Query: 502 NPYF-DNTEKTIEPWLLHGFDEDFYGEELRLVIVGYIRPEANFPSLESLIERIHED 338
            P    N EKT+E +L   F  D YGE++   I+  IR E  F SLESL ++I +D
Sbjct: 57  KPTVGSNLEKTLEIFLFD-FHRDIYGEKIECSILFKIREERRFDSLESLTKQIKKD 111

>RIBF_BUCAI (P57250) Riboflavin biosynthesis protein ribF [Includes: Riboflavin|
           kinase (EC 2.7.1.26) (Flavokinase); FMN
           adenylyltransferase (EC 2.7.7.2) (FAD pyrophosphorylase)
           (FAD synthetase)]
          Length = 313

 Score = 40.4 bits (93), Expect = 0.005
 Identities = 40/128 (31%), Positives = 59/128 (46%), Gaps = 3/128 (2%)
 Frame = -3

Query: 682 IGGPVIKGFGRGSKVLGIPTAN-LAAENFSDILSEHTSGVYFGWAGLSKRGIYKMVMSIG 506
           I G VI G   G + +  PTAN L ++NF       T+GVY              + +IG
Sbjct: 190 ISGRVIHGNKIG-RTMNYPTANILLSKNFL-----LTNGVYAVKIKYCPNKYAIGISNIG 243

Query: 505 WNPYFDNTEKT--IEPWLLHGFDEDFYGEELRLVIVGYIRPEANFPSLESLIERIHEDGR 332
             P F NT+K   +E +L      D YG+ + + I   IR E  FPS + L  +I +D  
Sbjct: 244 IKPSFSNTQKNKLLEVYLFD-IKIDLYGKYIEIFIYKKIRDEQFFPSKKELKNQISQDIL 302

Query: 331 IAENALDL 308
           I +   ++
Sbjct: 303 IVQKYFNI 310

>RIBF_HAEIN (P44957) Riboflavin biosynthesis protein ribF [Includes: Riboflavin|
           kinase (EC 2.7.1.26) (Flavokinase); FMN
           adenylyltransferase (EC 2.7.7.2) (FAD pyrophosphorylase)
           (FAD synthetase)]
          Length = 308

 Score = 40.0 bits (92), Expect = 0.007
 Identities = 34/120 (28%), Positives = 54/120 (45%)
 Frame = -3

Query: 682 IGGPVIKGFGRGSKVLGIPTANLAAENFSDILSEHTSGVYFGWAGLSKRGIYKMVMSIGW 503
           I G VI G   G + +G PTAN+      + +     GVY     L    I+  V ++G 
Sbjct: 190 IFGRVIHGNKLG-RTIGFPTANIRLHRQVNPIK----GVYAVKVRLKSGEIFNGVANMGK 244

Query: 502 NPYFDNTEKTIEPWLLHGFDEDFYGEELRLVIVGYIRPEANFPSLESLIERIHEDGRIAE 323
            P  +   + +E  L   F ++ YG+ + +     IR E  FPS + L  +I +D   A+
Sbjct: 245 RPTINGLMQLLEVHLFD-FSQNIYGQMVEVEFCHKIRNEIKFPSFDDLKVQIEKDVETAK 303

>RIBF_MYCPN (P75587) Putative riboflavin biosynthesis protein ribF [Includes:|
           Riboflavin kinase (EC 2.7.1.26) (Flavokinase); FMN
           adenylyltransferase (EC 2.7.7.2) (FAD pyrophosphorylase)
           (FAD synthetase)]
          Length = 269

 Score = 36.2 bits (82), Expect = 0.096
 Identities = 33/121 (27%), Positives = 58/121 (47%)
 Frame = -3

Query: 685 FIGGPVIKGFGRGSKVLGIPTANLAAENFSDILSEHTSGVYFGWAGLSKRGIYKMVMSIG 506
           F  G VI+G  + ++ LG PTAN+  + +   L   +  +   +   +  G+       G
Sbjct: 151 FREGVVIRG-NQQARFLGWPTANITLKPYMVPLRCGSYVITVTYHQTNYPGV-------G 202

Query: 505 WNPYFDNTEKTIEPWLLHGFDEDFYGEELRLVIVGYIRPEANFPSLESLIERIHEDGRIA 326
           +  Y  N +   E  L+ GF  D YG++LR     +IRP+  F  +++L + I  D + A
Sbjct: 203 FISY-KNDQLVCETHLI-GFSGDLYGKQLRFTFNQFIRPQQKFSGVQALQKAISGDLKQA 260

Query: 325 E 323
           +
Sbjct: 261 Q 261

>YLBP_BACSU (O34468) Uncharacterized N-acetyltransferase ylbP (EC 2.3.1.-)|
          Length = 160

 Score = 33.9 bits (76), Expect = 0.48
 Identities = 26/101 (25%), Positives = 46/101 (45%), Gaps = 7/101 (6%)
 Frame = -3

Query: 643 KVLGIPTANLAAENFSDILSEHTS----GVYFGWAGLSKRGIYKMVMSIGWNPYFDNTEK 476
           K  GI   ++  E   +I+   ++    G+YFG   +++  +Y++      NPYFDN + 
Sbjct: 21  KEYGIQELSMLEELQDNIIENDSTSPFYGIYFGDKLVARMSLYQVNGKS--NPYFDNRQD 78

Query: 475 TIEPW---LLHGFDEDFYGEELRLVIVGYIRPEANFPSLES 362
            +E W   +L G+    YG  L      +  P    P ++S
Sbjct: 79  YLELWKLEVLPGYQNRGYGRALVEFAKSFKMPIRTNPRMKS 119

>RIBF_MYCGE (P47391) Putative riboflavin biosynthesis protein ribF [Includes:|
           Riboflavin kinase (EC 2.7.1.26) (Flavokinase); FMN
           adenylyltransferase (EC 2.7.7.2) (FAD pyrophosphorylase)
           (FAD synthetase)]
          Length = 269

 Score = 33.5 bits (75), Expect = 0.63
 Identities = 29/117 (24%), Positives = 54/117 (46%)
 Frame = -3

Query: 676 GPVIKGFGRGSKVLGIPTANLAAENFSDILSEHTSGVYFGWAGLSKRGIYKMVMSIGWNP 497
           G V+ G  + +++LG PTAN+  +N    L++   G Y     L+ +  Y     IG+  
Sbjct: 151 GTVVHGLKK-ARLLGFPTANIVMDNHLLTLNK---GSYIVRVLLNNQTFY----GIGFIS 202

Query: 496 YFDNTEKTIEPWLLHGFDEDFYGEELRLVIVGYIRPEANFPSLESLIERIHEDGRIA 326
             D  +  +    +  F+ + YG  ++  ++ +IR  + F S  +L + I  D   A
Sbjct: 203 QKD--QDLVCETHIFNFNNEIYGSLVKFTLLKFIRTISKFSSQAALQKAIQSDANFA 257

>ACDE2_METMA (Q49164) Acetyl-CoA decarbonylase/synthase complex epsilon subunit|
           2 (ACDS complex epsilon subunit 2)
          Length = 170

 Score = 32.0 bits (71), Expect = 1.8
 Identities = 23/65 (35%), Positives = 31/65 (47%), Gaps = 11/65 (16%)
 Frame = -3

Query: 646 SKVLGIPTA----NLAAENFSDI----LSEHTSGVYF---GWAGLSKRGIYKMVMSIGWN 500
           SK   IP A    +LAA    D+    ++ H  G Y     W GL   G Y MV+SIG+ 
Sbjct: 58  SKTANIPIAATGSSLAALADKDVDAKYINAHMLGFYLTDPNWPGLDGNGNYDMVISIGFK 117

Query: 499 PYFDN 485
            ++ N
Sbjct: 118 KFYIN 122

>RIBF_PSEFL (P22990) Riboflavin biosynthesis protein ribF [Includes: Riboflavin|
           kinase (EC 2.7.1.26) (Flavokinase); FMN
           adenylyltransferase (EC 2.7.7.2) (FAD pyrophosphorylase)
           (FAD synthetase)]
          Length = 311

 Score = 31.2 bits (69), Expect = 3.1
 Identities = 36/123 (29%), Positives = 52/123 (42%), Gaps = 8/123 (6%)
 Frame = -3

Query: 682 IGGPVIKGFGRGSKVLGIPTANLAAENFSDILSEHTSGVYF--------GWAGLSKRGIY 527
           I G V+ G  + ++ LG PTAN+  +     L+    GVY          W G++  G+ 
Sbjct: 189 IAGRVLHG-QKLARQLGTPTANVQLKRRRVPLT----GVYLVSVDIDGQSWPGVANIGVR 243

Query: 526 KMVMSIGWNPYFDNTEKTIEPWLLHGFDEDFYGEELRLVIVGYIRPEANFPSLESLIERI 347
             V   G        +  +E  LL  F  D Y   L +V    +R E  F SLE+L   I
Sbjct: 244 PTVAGDG--------KAHLEVHLLD-FAGDLYDRRLTVVFHQKLREEQRFASLEALKTAI 294

Query: 346 HED 338
           + D
Sbjct: 295 NAD 297

>GCSP_CHICK (P15505) Glycine dehydrogenase [decarboxylating], mitochondrial|
           precursor (EC 1.4.4.2) (Glycine decarboxylase) (Glycine
           cleavage system P-protein)
          Length = 1004

 Score = 30.4 bits (67), Expect = 5.3
 Identities = 16/44 (36%), Positives = 23/44 (52%)
 Frame = -3

Query: 439 DFYGEELRLVIVGYIRPEANFPSLESLIERIHEDGRIAENALDL 308
           DF G+++  V+  Y   E        LIER H++G +A  A DL
Sbjct: 237 DFSGKDVSGVLFQYPDTEGKVEDFSELIERAHQNGTLACCATDL 280

>PTPA1_EMENI (Q5B6C5) Serine/threonine-protein phosphatase 2A activator 1 (EC|
           5.2.1.8) (Peptidyl-prolyl cis-trans isomerase PTPA-1)
           (PPIase PTPA-1) (Rotamase PTPA-1) (Phosphotyrosyl
           phosphatase activator 1)
          Length = 432

 Score = 30.4 bits (67), Expect = 5.3
 Identities = 12/25 (48%), Positives = 17/25 (68%)
 Frame = -3

Query: 463 WLLHGFDEDFYGEELRLVIVGYIRP 389
           W LHGF E+  G E R +++G I+P
Sbjct: 185 WKLHGFPENSPGVEERAIVLGVIQP 209

>VATA_HALVO (Q48332) V-type ATP synthase alpha chain (EC 3.6.3.14) (V-type|
           ATPase subunit A)
          Length = 586

 Score = 29.6 bits (65), Expect = 9.0
 Identities = 19/82 (23%), Positives = 41/82 (50%)
 Frame = -3

Query: 514 SIGWNPYFDNTEKTIEPWLLHGFDEDFYGEELRLVIVGYIRPEANFPSLESLIERIHEDG 335
           +I WN  +   ++ ++PW +   ++D + EE +  +   +  E N   L+ +++ + +D 
Sbjct: 431 AINWNESYSLYQEQLDPWFVENVEDD-WAEERQWAV--DVLDEEN--ELQEIVQLVGKDA 485

Query: 334 RIAENALDLPEYAKYKDSPYLR 269
              +  L L E A+Y    YL+
Sbjct: 486 LPEDQQLTL-EIARYLREAYLQ 506


  Database: uniprot_sprot.fasta
    Posted date:  May 25, 2006  5:36 PM
  Number of letters in database: 80,573,946
  Number of sequences in database:  219,361
  
Lambda     K      H
   0.318    0.135    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 103,629,197
Number of Sequences: 219361
Number of extensions: 2207602
Number of successful extensions: 6691
Number of sequences better than 10.0: 18
Number of HSP's better than 10.0 without gapping: 6435
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 6684
length of database: 80,573,946
effective HSP length: 108
effective length of database: 56,882,958
effective search space used: 6825954960
frameshift window, decay const: 50,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)