ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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| Clone Name | rbasd14c05 |
|---|---|
| Clone Library Name | barley_pub |
>SRK6_BRAOE (Q09092) Putative serine/threonine-protein kinase receptor precursor| (EC 2.7.11.1) (S-receptor kinase) (SRK) Length = 849 Score = 207 bits (528), Expect = 2e-53 Identities = 100/179 (55%), Positives = 132/179 (73%), Gaps = 6/179 (3%) Frame = -2 Query: 736 RIIHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTAYTLKVIGTYGYMSPEYAMDGVF 557 RIIHRD+K SN+LLD+NMIPKISDFG+AR+F D+T A T+KV+GTYGYMSPEYAM G+F Sbjct: 648 RIIHRDLKVSNILLDKNMIPKISDFGMARIFERDETEANTMKVVGTYGYMSPEYAMYGIF 707 Query: 556 SMKSDIYSFGVMVLEIVTGKKNRGFYDAELDLNLLGYAWTLWKEGRSTELLDEAMMGSSC 377 S KSD++SFGV+VLEIV+GKKNRGFY+ + + +LL Y W+ WKEGR+ E++D ++ S Sbjct: 708 SEKSDVFSFGVIVLEIVSGKKNRGFYNLDYENDLLSYVWSRWKEGRALEIVDPVIVDSLS 767 Query: 376 DH------SQVRRCIQVALLCVDMNPRNRPLMSSIVMMLATENATLPEPNEPGGNVGKS 218 +V +CIQ+ LLCV +RP MSS+V M +E +P+P PG V +S Sbjct: 768 SQPSIFQPQEVLKCIQIGLLCVQELAEHRPAMSSVVWMFGSEATEIPQPKPPGYCVRRS 826
>RLCK7_ARATH (Q9LQQ8) Probable serine/threonine-protein kinase RLCKVII (EC| 2.7.11.1) Length = 423 Score = 127 bits (319), Expect = 4e-29 Identities = 63/174 (36%), Positives = 107/174 (61%) Frame = -2 Query: 733 IIHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTAYTLKVIGTYGYMSPEYAMDGVFS 554 +I+RD+K SN+LL + PK+SDFG+A++ T + +V+GTYGY +P+YAM G + Sbjct: 226 VIYRDLKCSNILLGEDYQPKLSDFGLAKVGPSGDKTHVSTRVMGTYGYCAPDYAMTGQLT 285 Query: 553 MKSDIYSFGVMVLEIVTGKKNRGFYDAELDLNLLGYAWTLWKEGRSTELLDEAMMGSSCD 374 KSDIYSFGV++LE++TG+K D NL+G+A L+K+ R+ + + ++ Sbjct: 286 FKSDIYSFGVVLLELITGRKAIDNTKTRKDQNLVGWARPLFKDRRNFPKMVDPLLQGQYP 345 Query: 373 HSQVRRCIQVALLCVDMNPRNRPLMSSIVMMLATENATLPEPNEPGGNVGKSTS 212 + + + ++ +CV P RP++S +V+ L ++ +PN P + GK+ S Sbjct: 346 VRGLYQALAISAMCVQEQPTMRPVVSDVVLALNFLASSKYDPNSPSSSSGKNPS 399
>EXS_ARATH (Q9LYN8) Leucine-rich repeat receptor protein kinase EXS precursor| (EC 2.7.11.1) (Extra sporogenous cells protein) (EXCESS MICROSPOROCYTES1 protein) Length = 1192 Score = 115 bits (287), Expect = 2e-25 Identities = 61/154 (39%), Positives = 101/154 (65%), Gaps = 2/154 (1%) Frame = -2 Query: 733 IIHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTAYTLKVIGTYGYMSPEYAMDGVFS 554 IIHRD+KASN+LLD + PK++DFG+AR+ ++ T+ + GT+GY+ PEY + Sbjct: 1039 IIHRDIKASNILLDGDFEPKVADFGLARLISACESHVSTV-IAGTFGYIPPEYGQSARAT 1097 Query: 553 MKSDIYSFGVMVLEIVTGKKNRG--FYDAELDLNLLGYAWTLWKEGRSTELLDEAMMGSS 380 K D+YSFGV++LE+VTGK+ G F ++E NL+G+A +G++ +++D ++ + Sbjct: 1098 TKGDVYSFGVILLELVTGKEPTGPDFKESE-GGNLVGWAIQKINQGKAVDVIDPLLVSVA 1156 Query: 379 CDHSQVRRCIQVALLCVDMNPRNRPLMSSIVMML 278 +SQ+ R +Q+A+LC+ P RP M ++ L Sbjct: 1157 LKNSQL-RLLQIAMLCLAETPAKRPNMLDVLKAL 1189
>BRL3_ARATH (Q9LJF3) Serine/threonine-protein kinase BRI1-like 3 precursor (EC| 2.7.11.1) (BRASSINOSTEROID INSENSITIVE 1-like protein 3) Length = 1164 Score = 112 bits (281), Expect = 9e-25 Identities = 62/167 (37%), Positives = 98/167 (58%), Gaps = 6/167 (3%) Frame = -2 Query: 733 IIHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTAYTLKVIGTYGYMSPEYAMDGVFS 554 IIHRDMK+SNVLLD++ + ++SDFG+AR+ T + GT GY+ PEY + Sbjct: 981 IIHRDMKSSNVLLDQDFVARVSDFGMARLVSALDTHLSVSTLAGTPGYVPPEYYQSFRCT 1040 Query: 553 MKSDIYSFGVMVLEIVTGKKNRGFYDAELDLNLLGYAWTLWKEGRSTELLDEAMMGSSCD 374 K D+YS+GV++LE+++GKK + D NL+G+A L++E R E+LD ++ Sbjct: 1041 AKGDVYSYGVILLELLSGKKPIDPEEFGEDNNLVGWAKQLYREKRGAEILDPELVTDKSG 1100 Query: 373 HSQVRRCIQVALLCVDMNPRNRPLMSSIVMM------LATENATLPE 251 ++ +++A C+D P RP M ++ M + TEN +L E Sbjct: 1101 DVELLHYLKIASQCLDDRPFKRPTMIQVMTMFKELVQVDTENDSLDE 1147
>PBS1_ARATH (Q9FE20) Serine/threonine-protein kinase PBS1 (EC 2.7.11.1)| (AvrPphB susceptible protein 1) Length = 456 Score = 108 bits (271), Expect = 1e-23 Identities = 57/156 (36%), Positives = 95/156 (60%), Gaps = 3/156 (1%) Frame = -2 Query: 733 IIHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTAYTLKVIGTYGYMSPEYAMDGVFS 554 +I+RD K+SN+LLD PK+SDFG+A++ + + +V+GTYGY +PEYAM G + Sbjct: 209 VIYRDFKSSNILLDEGFHPKLSDFGLAKLGPTGDKSHVSTRVMGTYGYCAPEYAMTGQLT 268 Query: 553 MKSDIYSFGVMVLEIVTGKKNRGFYDAEL---DLNLLGYAWTLWKEGRSTELLDEAMMGS 383 +KSD+YSFGV+ LE++TG+K D+E+ + NL+ +A L+ + R L + + Sbjct: 269 VKSDVYSFGVVFLELITGRK---AIDSEMPHGEQNLVAWARPLFNDRRKFIKLADPRLKG 325 Query: 382 SCDHSQVRRCIQVALLCVDMNPRNRPLMSSIVMMLA 275 + + + VA +C+ RPL++ +V L+ Sbjct: 326 RFPTRALYQALAVASMCIQEQAATRPLIADVVTALS 361
>BRL1_ARATH (Q9ZWC8) Serine/threonine-protein kinase BRI1-like 1 precursor (EC| 2.7.11.1) (BRASSINOSTEROID INSENSITIVE 1-like protein 1) Length = 1166 Score = 107 bits (268), Expect = 3e-23 Identities = 59/161 (36%), Positives = 91/161 (56%) Frame = -2 Query: 733 IIHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTAYTLKVIGTYGYMSPEYAMDGVFS 554 IIHRDMK+SNVLLD + ++SDFG+AR+ T + GT GY+ PEY + Sbjct: 983 IIHRDMKSSNVLLDEDFEARVSDFGMARLVSALDTHLSVSTLAGTPGYVPPEYYQSFRCT 1042 Query: 553 MKSDIYSFGVMVLEIVTGKKNRGFYDAELDLNLLGYAWTLWKEGRSTELLDEAMMGSSCD 374 K D+YS+GV++LE+++GKK + D NL+G+A L++E R E+LD ++ Sbjct: 1043 AKGDVYSYGVILLELLSGKKPIDPGEFGEDNNLVGWAKQLYREKRGAEILDPELVTDKSG 1102 Query: 373 HSQVRRCIQVALLCVDMNPRNRPLMSSIVMMLATENATLPE 251 ++ +++A C+D P RP M ++ M A E Sbjct: 1103 DVELFHYLKIASQCLDDRPFKRPTMIQLMAMFKEMKADTEE 1143
>BAK1_ARATH (Q94F62) BRASSINOSTEROID INSENSITIVE 1-associated receptor kinase 1| precursor (EC 2.7.11.1) (BRI1-associated receptor kinase 1) (Somatic embryogenesis receptor-like kinase 3) Length = 615 Score = 107 bits (267), Expect = 4e-23 Identities = 65/157 (41%), Positives = 94/157 (59%), Gaps = 4/157 (2%) Frame = -2 Query: 736 RIIHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTAYTLKVIGTYGYMSPEYAMDGVF 557 +IIHRD+KA+N+LLD + DFG+A++ T T V GT G+++PEY G Sbjct: 411 KIIHRDVKAANILLDEEFEAVVGDFGLAKLMDYKDTHV-TTAVRGTIGHIAPEYLSTGKS 469 Query: 556 SMKSDIYSFGVMVLEIVTGKKNRGFYDAEL----DLNLLGYAWTLWKEGRSTELLDEAMM 389 S K+D++ +GVM+LE++TG+ R F A L D+ LL + L KE + L+D + Sbjct: 470 SEKTDVFGYGVMLLELITGQ--RAFDLARLANDDDVMLLDWVKGLLKEKKLEALVDVDLQ 527 Query: 388 GSSCDHSQVRRCIQVALLCVDMNPRNRPLMSSIVMML 278 G+ D +V + IQVALLC +P RP MS +V ML Sbjct: 528 GNYKD-EEVEQLIQVALLCTQSSPMERPKMSEVVRML 563
>BRL2_ARATH (Q9ZPS9) Serine/threonine-protein kinase BRI1-like 2 precursor (EC| 2.7.11.1) (BRASSINOSTEROID INSENSITIVE 1-like protein 2) (Protein VASCULAR HIGHWAY 1) Length = 1143 Score = 103 bits (256), Expect = 7e-22 Identities = 61/166 (36%), Positives = 93/166 (56%), Gaps = 14/166 (8%) Frame = -2 Query: 733 IIHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTAYTLKVIGTYGYMSPEYAMDGVFS 554 IIHRDMK+SNVLLD++M ++SDFG+AR+ T + GT GY+ PEY + Sbjct: 962 IIHRDMKSSNVLLDQDMEARVSDFGMARLISALDTHLSVSTLAGTPGYVPPEYYQSFRCT 1021 Query: 553 MKSDIYSFGVMVLEIVTGKKNRGFYDAELDLNLLGYAWTLWKEGRSTELLDEAMMGSSCD 374 K D+YS GV++LEI++GK+ + D NL+G++ +EG+ E++DE ++ Sbjct: 1022 AKGDVYSIGVVMLEILSGKRPTDKEEFG-DTNLVGWSKMKAREGKHMEVIDEDLLKEGSS 1080 Query: 373 HS--------------QVRRCIQVALLCVDMNPRNRPLMSSIVMML 278 S ++ R +++AL CVD P RP M +V L Sbjct: 1081 ESLNEKEGFEGGVIVKEMLRYLEIALRCVDDFPSKRPNMLQVVASL 1126
>PSKR_ARATH (Q9ZVR7) Putative phytosulfokine receptor precursor (EC 2.7.11.1)| (Phytosulfokine LRR receptor kinase) Length = 1008 Score = 102 bits (253), Expect = 2e-21 Identities = 53/152 (34%), Positives = 89/152 (58%) Frame = -2 Query: 733 IIHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTAYTLKVIGTYGYMSPEYAMDGVFS 554 I+HRD+K+SN+LLD N ++DFG+AR+ +T T ++GT GY+ PEY V + Sbjct: 856 ILHRDIKSSNILLDENFNSHLADFGLARLMSPYETHVST-DLVGTLGYIPPEYGQASVAT 914 Query: 553 MKSDIYSFGVMVLEIVTGKKNRGFYDAELDLNLLGYAWTLWKEGRSTELLDEAMMGSSCD 374 K D+YSFGV++LE++T K+ + +L+ + + E R++E+ D + D Sbjct: 915 YKGDVYSFGVVLLELLTDKRPVDMCKPKGCRDLISWVVKMKHESRASEVFDPLIYSKEND 974 Query: 373 HSQVRRCIQVALLCVDMNPRNRPLMSSIVMML 278 ++ R +++A LC+ NP+ RP +V L Sbjct: 975 -KEMFRVLEIACLCLSENPKQRPTTQQLVSWL 1005
>RPK1_IPONI (P93194) Receptor-like protein kinase precursor (EC 2.7.11.1)| Length = 1109 Score = 101 bits (251), Expect = 3e-21 Identities = 58/157 (36%), Positives = 93/157 (59%), Gaps = 5/157 (3%) Frame = -2 Query: 733 IIHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTAYTLKVIGTYGYMSPEYAMDGVFS 554 I+HRD+K N+LLD ++ P ISDFGIA++ T+ + V GT GYM+PE A V S Sbjct: 938 IVHRDIKPMNILLDSDLEPHISDFGIAKLLDQSATSIPSNTVQGTIGYMAPENAFTTVKS 997 Query: 553 MKSDIYSFGVMVLEIVTGKKNRG-FYDAELDLNLLGYAWTLWKE-GRSTELLDEAMMGSS 380 +SD+YS+GV++LE++T KK ++ E D ++G+ ++W + G +++D +++ Sbjct: 998 RESDVYSYGVVLLELITRKKALDPSFNGETD--IVGWVRSVWTQTGEIQKIVDPSLLDEL 1055 Query: 379 CDHS---QVRRCIQVALLCVDMNPRNRPLMSSIVMML 278 D S QV + +AL C + RP M +V L Sbjct: 1056 IDSSVMEQVTEALSLALRCAEKEVDKRPTMRDVVKQL 1092
>CX32_ARATH (P27450) Probable serine/threonine-protein kinase Cx32, chloroplast| precursor (EC 2.7.11.1) Length = 419 Score = 100 bits (248), Expect = 6e-21 Identities = 57/161 (35%), Positives = 95/161 (59%), Gaps = 9/161 (5%) Frame = -2 Query: 733 IIHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTAYTLKVIGTYGYMSPEYAMDGVFS 554 +I+RD KASN+LLD N K+SDFG+A++ D+ + T +++GTYGY +PEY G Sbjct: 214 VIYRDFKASNILLDSNYDAKLSDFGLAKLGPADEKSHVTTRIMGTYGYAAPEYMATGHLY 273 Query: 553 MKSDIYSFGVMVLEIVTG------KKNRGFYDAELDLNLLGYAW---TLWKEGRSTELLD 401 +KSD+++FGV++LEI+TG K+ RG ++ +D W L + R +++D Sbjct: 274 VKSDVFAFGVVLLEIMTGLTAHNTKRPRG-QESLVD-------WLRPELSNKHRVKQIMD 325 Query: 400 EAMMGSSCDHSQVRRCIQVALLCVDMNPRNRPLMSSIVMML 278 + + G ++ L C++ +P+NRP M +V +L Sbjct: 326 KGIKGQYTT-KVATEMARITLSCIEPDPKNRPHMKEVVEVL 365
>NORK_MEDTR (Q8L4H4) Nodulation receptor kinase precursor (EC 2.7.11.1) (Does not| make infections protein 2) (Symbiosis receptor-like kinase) (MtSYMRK) Length = 925 Score = 99.0 bits (245), Expect = 1e-20 Identities = 58/164 (35%), Positives = 99/164 (60%), Gaps = 1/164 (0%) Frame = -2 Query: 733 IIHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTAYTLKVIGTYGYMSPEYAMDGVFS 554 +IHRD+K+SN+LLD++M K++DFG ++ + + +L+V GT GY+ PEY S Sbjct: 718 VIHRDVKSSNILLDQSMCAKVADFGFSKYAPQEGDSYVSLEVRGTAGYLDPEYYKTQQLS 777 Query: 553 MKSDIYSFGVMVLEIVTGKKNRGFYDAELDLNLLGYAWTLWKEGRSTELLDEAMMGSSCD 374 KSD++SFGV++LEIV+G++ ++ +L+ +A + + E++D + G Sbjct: 778 EKSDVFSFGVVLLEIVSGREPLNIKRPRIEWSLVEWAKPYIRASKVDEIVDPGIKGGY-- 835 Query: 373 HSQ-VRRCIQVALLCVDMNPRNRPLMSSIVMMLATENATLPEPN 245 H++ + R ++VAL C++ RP M IV L E+A + E N Sbjct: 836 HAEALWRVVEVALQCLEPYSTYRPCMVDIVREL--EDALIIENN 877
>BRI1_LYCPE (Q8L899) Systemin receptor SR160 precursor (EC 2.7.11.1)| (Brassinosteroid LRR receptor kinase) Length = 1207 Score = 98.2 bits (243), Expect = 2e-20 Identities = 57/152 (37%), Positives = 88/152 (57%), Gaps = 1/152 (0%) Frame = -2 Query: 733 IIHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTAYTLKVIGTYGYMSPEYAMDGVFS 554 IIHRDMK+SNVLLD N+ ++SDFG+AR+ T + GT GY+ PEY S Sbjct: 1010 IIHRDMKSSNVLLDENLEARVSDFGMARLMSAMDTHLSVSTLAGTPGYVPPEYYQSFRCS 1069 Query: 553 MKSDIYSFGVMVLEIVTGKKNRGFYDAELDLNLLGYAWTLWKEGRSTELLDEAMMGSSCD 374 K D+YS+GV++LE++TGK+ D D NL+G+ L +G+ T++ D ++ Sbjct: 1070 TKGDVYSYGVVLLELLTGKQPTDSADFG-DNNLVGWV-KLHAKGKITDVFDRELLKEDAS 1127 Query: 373 -HSQVRRCIQVALLCVDMNPRNRPLMSSIVMM 281 ++ + ++VA C+D RP M ++ M Sbjct: 1128 IEIELLQHLKVACACLDDRHWKRPTMIQVMAM 1159
>BRI1_LYCES (Q8GUQ5) Brassinosteroid LRR receptor kinase precursor (EC 2.7.11.1)| (tBRI1) (Altered brassinolide sensitivity 1) (Systemin receptor SR160) Length = 1207 Score = 98.2 bits (243), Expect = 2e-20 Identities = 57/152 (37%), Positives = 88/152 (57%), Gaps = 1/152 (0%) Frame = -2 Query: 733 IIHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTAYTLKVIGTYGYMSPEYAMDGVFS 554 IIHRDMK+SNVLLD N+ ++SDFG+AR+ T + GT GY+ PEY S Sbjct: 1010 IIHRDMKSSNVLLDENLEARVSDFGMARLMSAMDTHLSVSTLAGTPGYVPPEYYQSFRCS 1069 Query: 553 MKSDIYSFGVMVLEIVTGKKNRGFYDAELDLNLLGYAWTLWKEGRSTELLDEAMMGSSCD 374 K D+YS+GV++LE++TGK+ D D NL+G+ L +G+ T++ D ++ Sbjct: 1070 TKGDVYSYGVVLLELLTGKQPTDSADFG-DNNLVGWV-KLHAKGKITDVFDRELLKEDAS 1127 Query: 373 -HSQVRRCIQVALLCVDMNPRNRPLMSSIVMM 281 ++ + ++VA C+D RP M ++ M Sbjct: 1128 IEIELLQHLKVACACLDDRHWKRPTMIQVMAM 1159
>NORK_PEA (Q8LKZ1) Nodulation receptor kinase precursor (EC 2.7.11.1)| Length = 924 Score = 98.2 bits (243), Expect = 2e-20 Identities = 58/164 (35%), Positives = 98/164 (59%), Gaps = 1/164 (0%) Frame = -2 Query: 733 IIHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTAYTLKVIGTYGYMSPEYAMDGVFS 554 +IHRD+K+SN+LLD +M K++DFG ++ + + +L+V GT GY+ PEY S Sbjct: 717 VIHRDVKSSNILLDHSMCAKVADFGFSKYAPQEGDSYVSLEVRGTAGYLDPEYYKTQQLS 776 Query: 553 MKSDIYSFGVMVLEIVTGKKNRGFYDAELDLNLLGYAWTLWKEGRSTELLDEAMMGSSCD 374 KSD++SFGV++LEIV+G++ ++ +L+ +A + + E++D + G Sbjct: 777 EKSDVFSFGVVLLEIVSGREPLNIKRPRVEWSLVEWAKPYIRASKVDEIVDPGIKGGY-- 834 Query: 373 HSQ-VRRCIQVALLCVDMNPRNRPLMSSIVMMLATENATLPEPN 245 H++ + R ++VAL C++ RP M IV L E+A + E N Sbjct: 835 HAEALWRVVEVALQCLEPYSTYRPCMVDIVREL--EDALIIENN 876
>RLK5_ARATH (P47735) Receptor-like protein kinase 5 precursor (EC 2.7.11.1)| Length = 999 Score = 95.9 bits (237), Expect = 1e-19 Identities = 65/189 (34%), Positives = 104/189 (55%), Gaps = 5/189 (2%) Frame = -2 Query: 733 IIHRDMKASNVLLDRNMIPKISDFGIARM--FGGDQTTAYTLKVIGTYGYMSPEYAMDGV 560 I+HRD+K+SN+LLD + K++DFGIA++ G +T + G+ GY++PEY Sbjct: 815 IVHRDVKSSNILLDSDYGAKVADFGIAKVGQMSGSKTPEAMSGIAGSCGYIAPEYVYTLR 874 Query: 559 FSMKSDIYSFGVMVLEIVTGKKNRGFYDAEL-DLNLLGYAWTLWKEGRSTELLDEAMMGS 383 + KSDIYSFGV++LE+VTGK+ D+EL D ++ + T + ++D + Sbjct: 875 VNEKSDIYSFGVVLLELVTGKQPT---DSELGDKDMAKWVCTALDKCGLEPVIDPKL--D 929 Query: 382 SCDHSQVRRCIQVALLCVDMNPRNRPLMSSIVMMLATENATLP--EPNEPGGNVGKSTSD 209 ++ + I + LLC P NRP M +V+ML + +P PN +S + Sbjct: 930 LKFKEEISKVIHIGLLCTSPLPLNRPSMRKVVIMLQEVSGAVPCSSPN----TSKRSKTG 985 Query: 208 GELSQTQSE 182 G+LS +E Sbjct: 986 GKLSPYYTE 994
>NAK_ARATH (P43293) Probable serine/threonine-protein kinase NAK (EC 2.7.11.1)| Length = 389 Score = 95.5 bits (236), Expect = 2e-19 Identities = 55/154 (35%), Positives = 93/154 (60%), Gaps = 4/154 (2%) Frame = -2 Query: 736 RIIHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTAYTLKVIGTYGYMSPEYAMDGVF 557 ++I+RD KASN+LLD N K+SDFG+AR + + +V+GT GY +PEY G Sbjct: 198 QVIYRDFKASNILLDSNYNAKLSDFGLARDGPMGDNSHVSTRVMGTQGYAAPEYLATGHL 257 Query: 556 SMKSDIYSFGVMVLEIVTGKKNRGFYDAELDLNLLGYAWT-LWKEGRSTELLDEAMMGSS 380 S+KSD+YSFGV++LE+++G++ + NL+ +A L + R ++D + G Sbjct: 258 SVKSDVYSFGVVLLELLSGRRAIDKNQPVGEHNLVDWARPYLTNKRRLLRVMDPRLQG-- 315 Query: 379 CDHSQVRRCIQVALL---CVDMNPRNRPLMSSIV 287 + R +++A+L C+ ++ ++RP M+ IV Sbjct: 316 --QYSLTRALKIAVLALDCISIDAKSRPTMNEIV 347
>BRI1_ARATH (O22476) BRASSINOSTEROID INSENSITIVE 1 precursor (EC 2.7.11.1)| (AtBRI1) (Brassinosteroid LRR receptor kinase) Length = 1196 Score = 94.0 bits (232), Expect = 4e-19 Identities = 57/151 (37%), Positives = 83/151 (54%) Frame = -2 Query: 733 IIHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTAYTLKVIGTYGYMSPEYAMDGVFS 554 IIHRDMK+SNVLLD N+ ++SDFG+AR+ T + GT GY+ PEY S Sbjct: 1005 IIHRDMKSSNVLLDENLEARVSDFGMARLMSAMDTHLSVSTLAGTPGYVPPEYYQSFRCS 1064 Query: 553 MKSDIYSFGVMVLEIVTGKKNRGFYDAELDLNLLGYAWTLWKEGRSTELLDEAMMGSSCD 374 K D+YS+GV++LE++TGK+ D D NL+G+ K S E M Sbjct: 1065 TKGDVYSYGVVLLELLTGKRPTDSPDFG-DNNLVGWVKQHAKLRISDVFDPELMKEDPAL 1123 Query: 373 HSQVRRCIQVALLCVDMNPRNRPLMSSIVMM 281 ++ + ++VA+ C+D RP M ++ M Sbjct: 1124 EIELLQHLKVAVACLDDRAWRRPTMVQVMAM 1154
>PSKR_DAUCA (Q8LPB4) Phytosulfokine receptor precursor (EC 2.7.11.1)| (Phytosulfokine LRR receptor kinase) Length = 1021 Score = 93.6 bits (231), Expect = 6e-19 Identities = 50/153 (32%), Positives = 86/153 (56%), Gaps = 1/153 (0%) Frame = -2 Query: 733 IIHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTAYTLKVIGTYGYMSPEYAMDGVFS 554 I+HRD+K+SN+LL + ++DFG+AR+ T T ++GT GY+ PEY V + Sbjct: 865 ILHRDIKSSNILLSDTFVAHLADFGLARLIL-PYDTHVTTDLVGTLGYIPPEYGQASVAT 923 Query: 553 MKSDIYSFGVMVLEIVTGKKNRGFYDAELDLNLLGYAWTLWKEGRSTELLDEAMMGSSCD 374 K D+YSFGV++LE++TG++ +L+ + + E R +E+ D + D Sbjct: 924 YKGDVYSFGVVLLELLTGRRPMDVCKPRGSRDLISWVLQMKTEKRESEIFDPFIYDK--D 981 Query: 373 HS-QVRRCIQVALLCVDMNPRNRPLMSSIVMML 278 H+ ++ +++A C+ NP+ RP +V L Sbjct: 982 HAEEMLLVLEIACRCLGENPKTRPTTQQLVSWL 1014
>CLV1_ARATH (Q9SYQ8) Receptor protein kinase CLAVATA1 precursor (EC 2.7.11.1)| Length = 980 Score = 92.8 bits (229), Expect = 1e-18 Identities = 52/159 (32%), Positives = 86/159 (54%), Gaps = 7/159 (4%) Frame = -2 Query: 733 IIHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTAYTLKVIGTYGYMSPEYAMDGVFS 554 I+HRD+K++N+LLD + ++DFG+A+ + + G+YGY++PEYA Sbjct: 813 ILHRDVKSNNILLDSDFEAHVADFGLAKFLVDGAASECMSSIAGSYGYIAPEYAYTLKVD 872 Query: 553 MKSDIYSFGVMVLEIVTGKKNRGFYDAELDLNLLGYAWTLWKEGRSTELLDEAMMGSSCD 374 KSD+YSFGV++LE++ GKK G + +D+ W E T+ D A++ + D Sbjct: 873 EKSDVYSFGVVLLELIAGKKPVGEFGEGVDI----VRWVRNTEEEITQPSDAAIVVAIVD 928 Query: 373 H-------SQVRRCIQVALLCVDMNPRNRPLMSSIVMML 278 + V ++A++CV+ RP M +V ML Sbjct: 929 PRLTGYPLTSVIHVFKIAMMCVEEEAAARPTMREVVHML 967
>CRI4_MAIZE (O24585) Putative receptor protein kinase CRINKLY4 precursor (EC| 2.7.11.1) Length = 901 Score = 89.7 bits (221), Expect = 8e-18 Identities = 53/152 (34%), Positives = 85/152 (55%) Frame = -2 Query: 733 IIHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTAYTLKVIGTYGYMSPEYAMDGVFS 554 +IHRD+K+SN+L+D + +++DFG++ + D T + GT GY+ PEY + Sbjct: 630 VIHRDIKSSNILIDEDHNARVADFGLSILGPADSGTPLSELPAGTLGYLDPEYYRLHYLT 689 Query: 553 MKSDIYSFGVMVLEIVTGKKNRGFYDAELDLNLLGYAWTLWKEGRSTELLDEAMMGSSCD 374 KSD+YSFGV++LEI++G+K E N++ +A L K G +LD + S D Sbjct: 690 TKSDVYSFGVVLLEILSGRKAIDMQFEE--GNIVEWAVPLIKAGDIFAILDPVLSPPS-D 746 Query: 373 HSQVRRCIQVALLCVDMNPRNRPLMSSIVMML 278 +++ VA CV M ++RP M + L Sbjct: 747 LEALKKIASVACKCVRMRGKDRPSMDKVTTAL 778
>TMK1_ARATH (P43298) Putative receptor protein kinase TMK1 precursor (EC| 2.7.11.1) Length = 942 Score = 88.6 bits (218), Expect = 2e-17 Identities = 50/155 (32%), Positives = 89/155 (57%), Gaps = 2/155 (1%) Frame = -2 Query: 730 IHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTAYTLKVIGTYGYMSPEYAMDGVFSM 551 IHRD+K SN+LL +M K++DFG+ R+ + + T ++ GT+GY++PEYA+ G + Sbjct: 714 IHRDLKPSNILLGDDMRAKVADFGLVRLAPEGKGSIET-RIAGTFGYLAPEYAVTGRVTT 772 Query: 550 KSDIYSFGVMVLEIVTGKKNRGFYDAELDLNLLGYAWTLW--KEGRSTELLDEAMMGSSC 377 K D+YSFGV+++E++TG+K+ E ++L+ + ++ KE + +D + Sbjct: 773 KVDVYSFGVILMELITGRKSLDESQPEESIHLVSWFKRMYINKEASFKKAIDTTIDLDEE 832 Query: 376 DHSQVRRCIQVALLCVDMNPRNRPLMSSIVMMLAT 272 + V ++A C P RP M V +L++ Sbjct: 833 TLASVHTVAELAGHCCAREPYQRPDMGHAVNILSS 867
>IRAK4_MOUSE (Q8R4K2) Interleukin-1 receptor-associated kinase 4 (EC 2.7.11.1)| (IRAK-4) Length = 459 Score = 85.9 bits (211), Expect = 1e-16 Identities = 59/162 (36%), Positives = 87/162 (53%), Gaps = 6/162 (3%) Frame = -2 Query: 730 IHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTAYTLKVIGTYGYMSPEYAMDGVFSM 551 IHRD+K++N+LLD++ KISDFG+AR T T +++GT YM+PE A+ G + Sbjct: 308 IHRDIKSANILLDKDFTAKISDFGLARASARLAQTVMTSRIVGTTAYMAPE-ALRGEITP 366 Query: 550 KSDIYSFGVMVLEIVTGKKNRGFYDAELDLN-----LLGYAWTLWKEGRSTE-LLDEAMM 389 KSDIYSFGV++LE++TG A +D N LL + E ++ E DE M Sbjct: 367 KSDIYSFGVVLLELITGL-------AAVDENREPQLLLDIKEEIEDEEKTIEDYTDEKM- 418 Query: 388 GSSCDHSQVRRCIQVALLCVDMNPRNRPLMSSIVMMLATENA 263 S D + V A C+ RP ++ + +L +A Sbjct: 419 -SDADPASVEAMYSAASQCLHEKKNRRPDIAKVQQLLQEMSA 459
>SIRK_ARATH (O64483) Senescence-induced receptor-like serine/threonine-protein| kinase precursor (FLG22-induced receptor-like kinase 1) Length = 876 Score = 84.7 bits (208), Expect = 3e-16 Identities = 46/152 (30%), Positives = 83/152 (54%) Frame = -2 Query: 733 IIHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTAYTLKVIGTYGYMSPEYAMDGVFS 554 I+HRD+K +N+LL+ + K++DFG++R F + + + V G+ GY+ PEY + Sbjct: 693 IVHRDVKPTNILLNEKLQAKMADFGLSRSFSVEGSGQISTVVAGSIGYLDPEYYSTRQMN 752 Query: 553 MKSDIYSFGVMVLEIVTGKKNRGFYDAELDLNLLGYAWTLWKEGRSTELLDEAMMGSSCD 374 KSD+YS GV++LE++TG+ E +++ + ++ G ++D+ + D Sbjct: 753 EKSDVYSLGVVLLEVITGQPAIASSKTE-KVHISDHVRSILANGDIRGIVDQRLR-ERYD 810 Query: 373 HSQVRRCIQVALLCVDMNPRNRPLMSSIVMML 278 + ++AL C + RP MS +VM L Sbjct: 811 VGSAWKMSEIALACTEHTSAQRPTMSQVVMEL 842
>APK1A_ARATH (Q06548) Protein kinase APK1A, chloroplast precursor (EC 2.7.11.1)| Length = 410 Score = 84.0 bits (206), Expect = 5e-16 Identities = 54/176 (30%), Positives = 92/176 (52%), Gaps = 3/176 (1%) Frame = -2 Query: 736 RIIHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTAYTLKVIGTYGYMSPEYAMDGVF 557 R+I+RD K SN+LLD K+SDFG+A+ + + +V+GT+GY +PEY G Sbjct: 198 RVIYRDFKTSNILLDSEYNAKLSDFGLAKDGPIGDKSHVSTRVMGTHGYAAPEYLATGHL 257 Query: 556 SMKSDIYSFGVMVLEIVTGKKNRGFYDAELDLNLLGYAWTLWKEGRSTELLDEAMMGSSC 377 + KSD+YSFGV++LE+++G++ + NL+ +A R + + + Sbjct: 258 TTKSDVYSFGVVLLELLSGRRAVDKNRPSGERNLVEWAKPYLVNKRKIFRVIDNRLQDQY 317 Query: 376 DHSQVRRCIQVALLCVDMNPRNRPLMSSIVMML---ATENATLPEPNEPGGNVGKS 218 + + ++L C+ + RP MS +V L + NA + GGN+ K+ Sbjct: 318 SMEEACKVATLSLRCLTTEIKLRPNMSEVVSHLEHIQSLNAAI------GGNMDKT 367
>APK1B_ARATH (P46573) Protein kinase APK1B, chloroplast precursor (EC 2.7.11.1)| Length = 412 Score = 83.2 bits (204), Expect = 8e-16 Identities = 50/167 (29%), Positives = 86/167 (51%) Frame = -2 Query: 733 IIHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTAYTLKVIGTYGYMSPEYAMDGVFS 554 +I+RD K SN+LLD K+SDFG+A+ + + +++GTYGY +PEY G + Sbjct: 200 VIYRDFKTSNILLDSEYNAKLSDFGLAKDGPTGDKSHVSTRIMGTYGYAAPEYLATGHLT 259 Query: 553 MKSDIYSFGVMVLEIVTGKKNRGFYDAELDLNLLGYAWTLWKEGRSTELLDEAMMGSSCD 374 KSD+YS+GV++LE+++G++ + L+ +A L R + + + Sbjct: 260 TKSDVYSYGVVLLEVLSGRRAVDKNRPPGEQKLVEWARPLLANKRKLFRVIDNRLQDQYS 319 Query: 373 HSQVRRCIQVALLCVDMNPRNRPLMSSIVMMLATENATLPEPNEPGG 233 + + +AL C+ + RP M+ +V L + NE GG Sbjct: 320 MEEACKVATLALRCLTFEIKLRPNMNEVVSHL----EHIQTLNEAGG 362
>IRAK4_HUMAN (Q9NWZ3) Interleukin-1 receptor-associated kinase 4 (EC 2.7.11.1)| (IRAK-4) (NY-REN-64 antigen) Length = 460 Score = 82.0 bits (201), Expect = 2e-15 Identities = 56/158 (35%), Positives = 83/158 (52%), Gaps = 1/158 (0%) Frame = -2 Query: 730 IHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTAYTLKVIGTYGYMSPEYAMDGVFSM 551 IHRD+K++N+LLD KISDFG+AR T T +++GT YM+PE A+ G + Sbjct: 308 IHRDIKSANILLDEAFTAKISDFGLARASEKFAQTVMTSRIVGTTAYMAPE-ALRGEITP 366 Query: 550 KSDIYSFGVMVLEIVTGKKNRGFYDAELDLNLLGYAWTLWKEGRSTE-LLDEAMMGSSCD 374 KSDIYSFGV++LEI+TG + LL + E ++ E +D+ M + D Sbjct: 367 KSDIYSFGVVLLEIITGLP--AVDEHREPQLLLDIKEEIEDEEKTIEDYIDKKM--NDAD 422 Query: 373 HSQVRRCIQVALLCVDMNPRNRPLMSSIVMMLATENAT 260 + V VA C+ RP + + +L A+ Sbjct: 423 STSVEAMYSVASQCLHEKKNKRPDIKKVQQLLQEMTAS 460
>KPEL_DROME (Q05652) Probable serine/threonine-protein kinase pelle (EC| 2.7.11.1) Length = 501 Score = 81.6 bits (200), Expect = 2e-15 Identities = 53/154 (34%), Positives = 84/154 (54%), Gaps = 5/154 (3%) Frame = -2 Query: 733 IIHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTAYTL-KVIGTYGYMSPEYAMDGVF 557 +IH D+K +N+LLD+ + PKI DFG+ R + KV GT Y+ PE+ Sbjct: 342 LIHGDIKPANILLDQCLQPKIGDFGLVREGPKSLDAVVEVNKVFGTKIYLPPEFRNFRQL 401 Query: 556 SMKSDIYSFGVMVLEIVTGKK-NRGFYDAELDLNLLGYAWTLWKEGRSTELLDE---AMM 389 S D+YSFG+++LE+ TG++ + E NLL Y W++ R ELL++ A M Sbjct: 402 STGVDVYSFGIVLLEVFTGRQVTDRVPENETKKNLLDYVKQQWRQNR-MELLEKHLAAPM 460 Query: 388 GSSCDHSQVRRCIQVALLCVDMNPRNRPLMSSIV 287 G D I+ L C ++P++RP M++++ Sbjct: 461 GKELDMCMC--AIEAGLHCTALDPQDRPSMNAVL 492
>KPRO_MAIZE (P17801) Putative receptor protein kinase ZmPK1 precursor (EC| 2.7.11.1) Length = 817 Score = 79.7 bits (195), Expect = 9e-15 Identities = 48/159 (30%), Positives = 82/159 (51%), Gaps = 7/159 (4%) Frame = -2 Query: 733 IIHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTAYTLKVIGTYGYMSPEYAMDGVFS 554 +IH D+K N+LLD+ PKI+DFG+ ++ +T V GT GY++PE+ + Sbjct: 654 VIHCDVKPENILLDQAFEPKITDFGLVKLLNRGGSTQNVSHVRGTLGYIAPEWVSSLPIT 713 Query: 553 MKSDIYSFGVMVLEIVTGKKNR----GFYDAELDLNLLGYAWTLWKEGRSTELLD---EA 395 K D+YS+GV++LE++TG + G + L L + EG +D ++ Sbjct: 714 AKVDVYSYGVVLLELLTGTRVSELVGGTDEVHSMLRKLVRMLSAKLEGEEQSWIDGYLDS 773 Query: 394 MMGSSCDHSQVRRCIQVALLCVDMNPRNRPLMSSIVMML 278 + ++ Q R I++A+ C++ + RP M V L Sbjct: 774 KLNRPVNYVQARTLIKLAVSCLEEDRSKRPTMEHAVQTL 812
>PKN1_THETN (Q8R9T6) Probable serine/threonine-protein kinase Sps1 (EC| 2.7.11.1) Length = 625 Score = 73.9 bits (180), Expect = 5e-13 Identities = 37/80 (46%), Positives = 52/80 (65%) Frame = -2 Query: 736 RIIHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTAYTLKVIGTYGYMSPEYAMDGVF 557 +IIHRD+K N+L+ + K++DFGIAR G T YT VIGT Y SPE A + Sbjct: 129 KIIHRDIKPQNILVTDEDVVKVTDFGIARAANG-ATITYTGDVIGTAYYFSPEQAKGSIV 187 Query: 556 SMKSDIYSFGVMVLEIVTGK 497 ++DIYS G+++ E++TGK Sbjct: 188 DERTDIYSLGIVLFEMLTGK 207
>IRAK1_MOUSE (Q62406) Interleukin-1 receptor-associated kinase 1 (EC 2.7.11.1)| (IRAK-1) (IRAK) (Pelle-like protein kinase) (mPLK) Length = 710 Score = 71.2 bits (173), Expect = 3e-12 Identities = 37/87 (42%), Positives = 54/87 (62%), Gaps = 7/87 (8%) Frame = -2 Query: 733 IIHRDMKASNVLLDRNMIPKISDFGIARM--FGG-----DQTTAYTLKVIGTYGYMSPEY 575 +IH D+K+SNVLLD ++PK+ DFG+AR F G T A T V GT Y+ EY Sbjct: 336 LIHGDIKSSNVLLDERLMPKLGDFGLARFSRFAGAKASQSSTVARTSTVRGTLAYLPEEY 395 Query: 574 AMDGVFSMKSDIYSFGVMVLEIVTGKK 494 G ++ +D +SFGV++LE + G++ Sbjct: 396 IKTGRLAVDTDTFSFGVVILETLAGQR 422
>PKN2_BACSU (O34507) Probable serine/threonine-protein kinase yloP (EC| 2.7.11.1) Length = 648 Score = 69.7 bits (169), Expect = 9e-12 Identities = 33/80 (41%), Positives = 53/80 (66%) Frame = -2 Query: 736 RIIHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTAYTLKVIGTYGYMSPEYAMDGVF 557 +I+HRD+K N+L+D K++DFGIA T +T V+G+ Y+SPE A G+ Sbjct: 129 QIVHRDIKPHNILIDHMGNIKVTDFGIATALSST-TITHTNSVLGSVHYLSPEQARGGLA 187 Query: 556 SMKSDIYSFGVMVLEIVTGK 497 + KSDIY+ G+++ E++TG+ Sbjct: 188 TKKSDIYALGIVLFELLTGR 207
>PKN2_CLOAB (Q97IC2) Probable serine/threonine protein kinase CAC1728 (EC| 2.7.11.1) Length = 657 Score = 69.3 bits (168), Expect = 1e-11 Identities = 43/142 (30%), Positives = 74/142 (52%) Frame = -2 Query: 733 IIHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTAYTLKVIGTYGYMSPEYAMDGVFS 554 I+HRD+K N+++ + I K++DFGIA+ + T T KV+G+ Y+SPE A Sbjct: 129 IVHRDIKPHNIMVTDDDIIKVTDFGIAKA-SNESTITTTNKVVGSAHYLSPEQAQGIPVD 187 Query: 553 MKSDIYSFGVMVLEIVTGKKNRGFYDAELDLNLLGYAWTLWKEGRSTELLDEAMMGSSCD 374 ++DIYSFG+++ E+ TGK YDA+ +++ + D A+ + + Sbjct: 188 CRTDIYSFGIVLYEMATGKVP---YDADTPVSI-----------ALKHIQDAAVPPNELN 233 Query: 373 HSQVRRCIQVALLCVDMNPRNR 308 ++ L C++ P NR Sbjct: 234 KDIPIALNKMILRCIEKKPENR 255
>PKNB_MYCLE (P54744) Probable serine/threonine-protein kinase pknB (EC| 2.7.11.1) Length = 622 Score = 69.3 bits (168), Expect = 1e-11 Identities = 33/79 (41%), Positives = 47/79 (59%) Frame = -2 Query: 733 IIHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTAYTLKVIGTYGYMSPEYAMDGVFS 554 IIHRD+K +N+++ K+ DFGIAR + T VIGT Y+SPE A Sbjct: 134 IIHRDVKPANIMISATNAVKVMDFGIARAIADSTSVTQTAAVIGTAQYLSPEQARGDSVD 193 Query: 553 MKSDIYSFGVMVLEIVTGK 497 +SD+YS G ++ EI+TG+ Sbjct: 194 ARSDVYSLGCVLYEILTGE 212
>IRAK1_HUMAN (P51617) Interleukin-1 receptor-associated kinase 1 (EC 2.7.11.1)| (IRAK-1) Length = 712 Score = 68.9 bits (167), Expect = 2e-11 Identities = 37/87 (42%), Positives = 53/87 (60%), Gaps = 7/87 (8%) Frame = -2 Query: 733 IIHRDMKASNVLLDRNMIPKISDFGIARM--FGGDQTT-----AYTLKVIGTYGYMSPEY 575 +IH D+K+SNVLLD + PK+ DFG+AR F G + A T V GT Y+ EY Sbjct: 336 LIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEY 395 Query: 574 AMDGVFSMKSDIYSFGVMVLEIVTGKK 494 G ++ +D +SFGV+VLE + G++ Sbjct: 396 IKTGRLAVDTDTFSFGVVVLETLAGQR 422
>PKSC_STRCO (Q9S2C0) Serine/threonine protein kinase pksC (EC 2.7.11.1)| Length = 556 Score = 68.6 bits (166), Expect = 2e-11 Identities = 33/80 (41%), Positives = 52/80 (65%), Gaps = 1/80 (1%) Frame = -2 Query: 733 IIHRDMKASNVLLDRNMIPKISDFGIAR-MFGGDQTTAYTLKVIGTYGYMSPEYAMDGVF 557 ++HRD+K NV++ + + K+ DFGIAR M G + T V+GT Y+SPE A+ Sbjct: 147 LVHRDIKPGNVMMTKRGVVKVMDFGIARAMQSGVTSMTQTGMVVGTPQYLSPEQALGRGV 206 Query: 556 SMKSDIYSFGVMVLEIVTGK 497 +SD+YS G+M+ ++VTG+ Sbjct: 207 DARSDLYSVGIMLFQLVTGR 226
>NEK9_MOUSE (Q8K1R7) Serine/threonine-protein kinase Nek9 (EC 2.7.11.1)| (NimA-related protein kinase 9) (Never in mitosis A-related kinase 9) Length = 984 Score = 68.6 bits (166), Expect = 2e-11 Identities = 44/150 (29%), Positives = 75/150 (50%), Gaps = 1/150 (0%) Frame = -2 Query: 733 IIHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTAYTLKVIGTYGYMSPEYAMDGVFS 554 I+HRD+K N+ L + + K+ D+G+A+ + + A TL +GT YMSPE ++ Sbjct: 172 ILHRDIKTLNIFLTKANLIKLGDYGLAKKLNSEYSMAETL--VGTPYYMSPELCQGVKYN 229 Query: 553 MKSDIYSFGVMVLEIVTGKKNRGFYDAELDLNLLGYAWTLWKEGRSTELLDEAMMGSSCD 374 KSDI++ G ++ E++T K+ +DA LNL + + + D Sbjct: 230 FKSDIWAVGCVIFELLTLKRT---FDATNPLNL-------------CVKIVQGIRAMEVD 273 Query: 373 HSQVR-RCIQVALLCVDMNPRNRPLMSSIV 287 SQ IQ+ C+D +P RP +++ Sbjct: 274 SSQYSLELIQLVHACLDQDPEQRPAADALL 303
>YES_CHICK (P09324) Tyrosine-protein kinase Yes (EC 2.7.10.2) (p61-Yes)| Length = 540 Score = 67.8 bits (164), Expect = 3e-11 Identities = 52/179 (29%), Positives = 89/179 (49%), Gaps = 8/179 (4%) Frame = -2 Query: 739 LRIIHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTA-----YTLKVIGTYGYMSPEY 575 + IHRD++A+N+L+ N++ KI+DFG+AR+ ++ TA + +K + +PE Sbjct: 387 MNYIHRDLRAANILVGDNLVCKIADFGLARLIEDNEYTARQGAKFPIK------WTAPEA 440 Query: 574 AMDGVFSMKSDIYSFGVMVLEIVTGKKNRGFYDAELDLNLLGYAWTLWKEGRSTELLDEA 395 A+ G F++KSD++SFG+++ E+VT K R Y + + E+L++ Sbjct: 441 ALYGRFTIKSDVWSFGILLTELVT--KGRVPYPGMV----------------NREVLEQV 482 Query: 394 MMG--SSCDHSQVRRCIQVALLCVDMNPRNRPLMSSIVMMLATENATLPEPN-EPGGNV 227 G C ++ LC +P RP I L + T EP +PG N+ Sbjct: 483 ERGYRMPCPQGCPESLHELMKLCWKKDPDERPTFEYIQSFL-EDYFTATEPQYQPGDNL 540
>PKNX_STRCO (Q9XA16) Probable serine/threonine-protein kinase SCO3848 (EC| 2.7.11.1) Length = 673 Score = 67.8 bits (164), Expect = 3e-11 Identities = 36/78 (46%), Positives = 48/78 (61%), Gaps = 1/78 (1%) Frame = -2 Query: 733 IIHRDMKASNVLLDRNMIPKISDFGIARMFG-GDQTTAYTLKVIGTYGYMSPEYAMDGVF 557 I+HRD+K +NV+L RN K+ DFGIAR G T T VIGT Y+SPE A Sbjct: 134 IVHRDIKPANVMLTRNGQVKVMDFGIARAMGDSGMTMTQTAAVIGTAQYLSPEQAKGEQV 193 Query: 556 SMKSDIYSFGVMVLEIVT 503 +SD+YS G ++ E++T Sbjct: 194 DARSDLYSTGCLLYELLT 211
>NEK9_HUMAN (Q8TD19) Serine/threonine-protein kinase Nek9 (EC 2.7.11.1)| (NimA-related protein kinase 9) (Never in mitosis A-related kinase 9) (Nercc1 kinase) (NIMA-related kinase 8) (Nek8) Length = 979 Score = 67.8 bits (164), Expect = 3e-11 Identities = 44/150 (29%), Positives = 74/150 (49%), Gaps = 1/150 (0%) Frame = -2 Query: 733 IIHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTAYTLKVIGTYGYMSPEYAMDGVFS 554 I+HRD+K N+ L + + K+ D+G+A+ + + A TL +GT YMSPE ++ Sbjct: 172 ILHRDIKTLNIFLTKANLIKLGDYGLAKKLNSEYSMAETL--VGTPYYMSPELCQGVKYN 229 Query: 553 MKSDIYSFGVMVLEIVTGKKNRGFYDAELDLNLLGYAWTLWKEGRSTELLDEAMMGSSCD 374 KSDI++ G ++ E++T K+ +DA LNL + + + D Sbjct: 230 FKSDIWAVGCVIFELLTLKRT---FDATNPLNL-------------CVKIVQGIRAMEVD 273 Query: 373 HSQVR-RCIQVALLCVDMNPRNRPLMSSIV 287 SQ IQ+ C+D +P RP ++ Sbjct: 274 SSQYSLELIQMVHSCLDQDPEQRPTADELL 303
>PKN5_MYXXA (P54737) Serine/threonine-protein kinase pkn5 (EC 2.7.11.1)| Length = 380 Score = 67.4 bits (163), Expect = 4e-11 Identities = 27/79 (34%), Positives = 51/79 (64%) Frame = -2 Query: 733 IIHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTAYTLKVIGTYGYMSPEYAMDGVFS 554 ++HRD+K SN+++D + ++ DFG+A+ D K++GTY YM+PE + Sbjct: 240 LVHRDLKPSNIMVDDDRQVRLMDFGLAKFLADDAAITEAGKLVGTYRYMAPEQILGEPLD 299 Query: 553 MKSDIYSFGVMVLEIVTGK 497 ++D+YS GV++ E+++G+ Sbjct: 300 GRADLYSLGVILYELLSGR 318
>YES_MOUSE (Q04736) Proto-oncogene tyrosine-protein kinase Yes (EC 2.7.10.2)| (p61-Yes) (c-Yes) Length = 540 Score = 67.0 bits (162), Expect = 6e-11 Identities = 53/179 (29%), Positives = 88/179 (49%), Gaps = 8/179 (4%) Frame = -2 Query: 739 LRIIHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTA-----YTLKVIGTYGYMSPEY 575 + IHRD++A+N+L+ N+I KI+DFG+AR+ ++ TA + +K + +PE Sbjct: 387 MNYIHRDLRAANILVGENLICKIADFGLARLIEDNEYTARQGAKFPIK------WTAPEA 440 Query: 574 AMDGVFSMKSDIYSFGVMVLEIVTGKKNRGFYDAELDLNLLGYAWTLWKEGRSTELLDEA 395 A+ G F++KSD++SFG++ E+VT K R Y + + E+L++ Sbjct: 441 ALYGRFTIKSDVWSFGILQTELVT--KGRVPYPGMV----------------NREVLEQV 482 Query: 394 MMG--SSCDHSQVRRCIQVALLCVDMNPRNRPLMSSIVMMLATENATLPEPN-EPGGNV 227 G C ++ LC +P RP I L + T EP +PG N+ Sbjct: 483 ERGYRMPCPQGCPESLHELMNLCWKKDPDERPTFEYIQSFL-EDYFTATEPQYQPGENL 540
>YES_HUMAN (P07947) Proto-oncogene tyrosine-protein kinase Yes (EC 2.7.10.2)| (p61-Yes) (c-Yes) Length = 542 Score = 66.6 bits (161), Expect = 8e-11 Identities = 52/179 (29%), Positives = 88/179 (49%), Gaps = 8/179 (4%) Frame = -2 Query: 739 LRIIHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTA-----YTLKVIGTYGYMSPEY 575 + IHRD++A+N+L+ N++ KI+DFG+AR+ ++ TA + +K + +PE Sbjct: 389 MNYIHRDLRAANILVGENLVCKIADFGLARLIEDNEYTARQGAKFPIK------WTAPEA 442 Query: 574 AMDGVFSMKSDIYSFGVMVLEIVTGKKNRGFYDAELDLNLLGYAWTLWKEGRSTELLDEA 395 A+ G F++KSD++SFG++ E+VT K R Y + + E+L++ Sbjct: 443 ALYGRFTIKSDVWSFGILQTELVT--KGRVPYPGMV----------------NREVLEQV 484 Query: 394 MMG--SSCDHSQVRRCIQVALLCVDMNPRNRPLMSSIVMMLATENATLPEPN-EPGGNV 227 G C ++ LC +P RP I L + T EP +PG N+ Sbjct: 485 ERGYRMPCPQGCPESLHELMNLCWKKDPDERPTFEYIQSFL-EDYFTATEPQYQPGENL 542
>STE7_YEAST (P06784) Serine/threonine-protein kinase STE7 (EC 2.7.12.2)| Length = 515 Score = 66.2 bits (160), Expect = 1e-10 Identities = 32/80 (40%), Positives = 51/80 (63%) Frame = -2 Query: 736 RIIHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTAYTLKVIGTYGYMSPEYAMDGVF 557 +IIHRD+K SNVL++ K+ DFG+++ + +GT YMSPE V+ Sbjct: 326 KIIHRDIKPSNVLINSKGQIKLCDFGVSKKLINSIADTF----VGTSTYMSPERIQGNVY 381 Query: 556 SMKSDIYSFGVMVLEIVTGK 497 S+K D++S G+M++E+VTG+ Sbjct: 382 SIKGDVWSLGLMIIELVTGE 401
>NEK7_MOUSE (Q9ES74) Serine/threonine-protein kinase Nek7 (EC 2.7.11.1)| (NimA-related protein kinase 7) Length = 302 Score = 66.2 bits (160), Expect = 1e-10 Identities = 41/144 (28%), Positives = 70/144 (48%) Frame = -2 Query: 736 RIIHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTAYTLKVIGTYGYMSPEYAMDGVF 557 R++HRD+K +NV + + K+ D G+ R F T A++L +GT YMSPE + + Sbjct: 156 RVMHRDIKPANVFITATGVVKLGDLGLGRFFSSKTTAAHSL--VGTPYYMSPERIHENGY 213 Query: 556 SMKSDIYSFGVMVLEIVTGKKNRGFYDAELDLNLLGYAWTLWKEGRSTELLDEAMMGSSC 377 + KSDI+S G ++ E+ A L G L+ + E D + S Sbjct: 214 NFKSDIWSLGCLLYEM-----------AALQSPFYGDKMNLYSLCKKIEQCDYPPLPSDH 262 Query: 376 DHSQVRRCIQVALLCVDMNPRNRP 305 ++R+ + + C++ +P RP Sbjct: 263 YSEELRQLVNI---CINPDPEKRP 283
>YRK_CHICK (Q02977) Proto-oncogene tyrosine-protein kinase Yrk (EC 2.7.10.2)| (p60-Yrk) (Yes-related kinase) Length = 535 Score = 66.2 bits (160), Expect = 1e-10 Identities = 32/84 (38%), Positives = 58/84 (69%), Gaps = 5/84 (5%) Frame = -2 Query: 739 LRIIHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTA-----YTLKVIGTYGYMSPEY 575 + IHRD++A+N+L+ N++ KI+DFG+AR+ ++ TA + +K + +PE Sbjct: 382 MNYIHRDLRAANILVGDNLVCKIADFGLARLIEDNEYTARQGAKFPIK------WTAPEA 435 Query: 574 AMDGVFSMKSDIYSFGVMVLEIVT 503 A+ G F++KSD++SFG+++ E+VT Sbjct: 436 ALFGKFTIKSDVWSFGILLTELVT 459
>FIN1_SCHPO (O13839) G2-specific protein kinase fin1 (EC 2.7.11.1)| Length = 722 Score = 66.2 bits (160), Expect = 1e-10 Identities = 46/167 (27%), Positives = 77/167 (46%), Gaps = 6/167 (3%) Frame = -2 Query: 733 IIHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTAYTLKVIGTYGYMSPEYAMDGVFS 554 ++HRD+K +N+ LD N K+ DFG++++ D T +T +GT YMSPE +S Sbjct: 147 VLHRDIKPANIFLDENNSVKLGDFGLSKLL--DNTRVFTQSYVGTPYYMSPEIIRSSPYS 204 Query: 553 MKSDIYSFGVMVLEI-VTGKKNRGFYDAELDLNLLGYAWTLWKEGRSTELLDEAMMGSSC 377 KSD+++ G ++ EI + G EL N+ + W S ++ Sbjct: 205 AKSDVWALGCVIFEICMLTHPFEGRSYLELQRNICQGNLSCWDHHYSDDVF--------- 255 Query: 376 DHSQVRRCIQVALLCVDMNPR-----NRPLMSSIVMMLATENATLPE 251 +R C++V D+ P P++S I L +E L + Sbjct: 256 --LLIRHCLEVN---SDLRPTTYQLLRSPILSDIRSKLESERVVLEQ 297
>FYN_XIPHE (P27446) Proto-oncogene tyrosine-protein kinase FYN (EC 2.7.10.2)| (P59-FYN) Length = 536 Score = 65.9 bits (159), Expect = 1e-10 Identities = 50/179 (27%), Positives = 88/179 (49%), Gaps = 8/179 (4%) Frame = -2 Query: 739 LRIIHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTA-----YTLKVIGTYGYMSPEY 575 + IHRD++++N+L+ N++ KI+DFG+AR+ ++ TA + +K + +PE Sbjct: 383 MNYIHRDLRSANILVGDNLVCKIADFGLARLIEDNEYTARQGAKFPIK------WTAPEA 436 Query: 574 AMDGVFSMKSDIYSFGVMVLEIVTGKKNRGFYDAELDLNLLGYAWTLWKEGRSTELLDEA 395 A+ G F++KSD++SFG+++ E+VT K R Y + E+L++ Sbjct: 437 ALYGRFTIKSDVWSFGILLTELVT--KGRVPYPGM----------------NNREVLEQV 478 Query: 394 MMG--SSCDHSQVRRCIQVALLCVDMNPRNRPLMSSIVMMLATENATLPEPN-EPGGNV 227 G C ++ L C +P RP + L + T EP +PG N+ Sbjct: 479 ERGYRMPCPQDCPASLHELMLQCWKKDPEERPTFEYLQAFL-EDYFTATEPQYQPGDNL 536
>NEK7_HUMAN (Q8TDX7) Serine/threonine-protein kinase Nek7 (EC 2.7.11.1)| (NimA-related protein kinase 7) Length = 302 Score = 65.9 bits (159), Expect = 1e-10 Identities = 42/144 (29%), Positives = 70/144 (48%) Frame = -2 Query: 736 RIIHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTAYTLKVIGTYGYMSPEYAMDGVF 557 R++HRD+K +NV + + K+ D G+ R F T A++L +GT YMSPE + + Sbjct: 156 RVMHRDIKPANVFITATGVVKLGDLGLGRFFSSKTTAAHSL--VGTPYYMSPERIHENGY 213 Query: 556 SMKSDIYSFGVMVLEIVTGKKNRGFYDAELDLNLLGYAWTLWKEGRSTELLDEAMMGSSC 377 + KSDI+S G ++ E+ A L G L+ + E D + S Sbjct: 214 NFKSDIWSLGCLLYEM-----------AALQSPFYGDKMNLYSLCKKIEQCDYPPLPSDH 262 Query: 376 DHSQVRRCIQVALLCVDMNPRNRP 305 ++R Q+ +C++ +P RP Sbjct: 263 YSEELR---QLVNMCINPDPEKRP 283
>YES_AVISY (P00527) Tyrosine-protein kinase transforming protein YES (EC| 2.7.10.2) (Fragment) Length = 528 Score = 65.9 bits (159), Expect = 1e-10 Identities = 32/84 (38%), Positives = 58/84 (69%), Gaps = 5/84 (5%) Frame = -2 Query: 739 LRIIHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTA-----YTLKVIGTYGYMSPEY 575 + IHRD++A+N+L+ N++ KI+DFG+AR+ ++ TA + +K + +PE Sbjct: 380 MNYIHRDLRAANILVGDNLVCKIADFGLARLIEDNEYTARQGAKFPIK------WTAPEA 433 Query: 574 AMDGVFSMKSDIYSFGVMVLEIVT 503 A+ G F++KSD++SFG+++ E+VT Sbjct: 434 ALYGRFTIKSDVWSFGILLTELVT 457
>YES_XIPHE (P27447) Tyrosine-protein kinase Yes (EC 2.7.10.2) (p61-Yes)| Length = 543 Score = 65.5 bits (158), Expect = 2e-10 Identities = 32/84 (38%), Positives = 58/84 (69%), Gaps = 5/84 (5%) Frame = -2 Query: 739 LRIIHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTA-----YTLKVIGTYGYMSPEY 575 + IHRD++A+N+L+ N++ KI+DFG+AR+ ++ TA + +K + +PE Sbjct: 390 MNYIHRDLRAANILVADNLVCKIADFGLARLIEDNEYTARQGAKFPIK------WTAPEA 443 Query: 574 AMDGVFSMKSDIYSFGVMVLEIVT 503 A+ G F++KSD++SFG+++ E+VT Sbjct: 444 ALYGRFTIKSDVWSFGILLTELVT 467
>KSG1_SCHPO (Q12701) Serine/threonine-protein kinase ksg1 (EC 2.7.11.1)| Length = 592 Score = 65.5 bits (158), Expect = 2e-10 Identities = 33/91 (36%), Positives = 52/91 (57%), Gaps = 12/91 (13%) Frame = -2 Query: 733 IIHRDMKASNVLLDRNMIPKISDFGIARMFG------------GDQTTAYTLKVIGTYGY 590 +IHRD+K N+LLD NM KI+DFG A++ D+ A++ +GT Y Sbjct: 219 VIHRDLKPENILLDDNMRTKITDFGSAKILNSSHGSHEEDTHHADKPQAHSRSFVGTARY 278 Query: 589 MSPEYAMDGVFSMKSDIYSFGVMVLEIVTGK 497 +SPE D + SDI++FG ++ +++ GK Sbjct: 279 VSPEVLSDKIAGTASDIWAFGCILFQMLAGK 309
>YES_XENLA (P10936) Tyrosine-protein kinase Yes (EC 2.7.10.2) (p61-Yes)| Length = 536 Score = 65.5 bits (158), Expect = 2e-10 Identities = 51/179 (28%), Positives = 88/179 (49%), Gaps = 8/179 (4%) Frame = -2 Query: 739 LRIIHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTA-----YTLKVIGTYGYMSPEY 575 + IHRD++A+N+L+ N++ KI+DFG+AR+ ++ TA + +K + +PE Sbjct: 383 MNYIHRDLRAANILVGDNLVCKIADFGLARLIEDNEYTARQGAKFPIK------WTAPEA 436 Query: 574 AMDGVFSMKSDIYSFGVMVLEIVTGKKNRGFYDAELDLNLLGYAWTLWKEGRSTELLDEA 395 A+ G F++KSD++SFG+++ E+V K R Y + + E+L++ Sbjct: 437 ALYGRFTIKSDVWSFGILLTELVA--KGRVPYPGMV----------------NREVLEQV 478 Query: 394 MMG--SSCDHSQVRRCIQVALLCVDMNPRNRPLMSSIVMMLATENATLPEPN-EPGGNV 227 G C ++ LC +P RP I L + T EP +PG N+ Sbjct: 479 ERGYRMPCPQRCPESLHELMKLCWKKDPDERPTFEYIQSFL-EDYFTATEPQYQPGDNL 536
>PKNL_MYCTU (O53510) Probable serine/threonine-protein kinase pknL (EC| 2.7.11.1) Length = 399 Score = 65.1 bits (157), Expect = 2e-10 Identities = 31/78 (39%), Positives = 49/78 (62%) Frame = -2 Query: 733 IIHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTAYTLKVIGTYGYMSPEYAMDGVFS 554 ++HRD+K N+L+ + K++DFG+ R T+ T ++GT Y+SPE DG Sbjct: 138 LVHRDVKPENILISDDGDVKLADFGLVRAVAAASITS-TGVILGTAAYLSPEQVRDGNAD 196 Query: 553 MKSDIYSFGVMVLEIVTG 500 +SD+YS GV+V E++TG Sbjct: 197 PRSDVYSVGVLVYELLTG 214
>PKNL_MYCBO (Q7TYY6) Probable serine/threonine-protein kinase pknL (EC| 2.7.11.1) Length = 399 Score = 65.1 bits (157), Expect = 2e-10 Identities = 31/78 (39%), Positives = 49/78 (62%) Frame = -2 Query: 733 IIHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTAYTLKVIGTYGYMSPEYAMDGVFS 554 ++HRD+K N+L+ + K++DFG+ R T+ T ++GT Y+SPE DG Sbjct: 138 LVHRDVKPENILISDDGDVKLADFGLVRAVAAASITS-TGVILGTAAYLSPEQVRDGNAD 196 Query: 553 MKSDIYSFGVMVLEIVTG 500 +SD+YS GV+V E++TG Sbjct: 197 PRSDVYSVGVLVYELLTG 214
>YES_CANFA (Q28923) Proto-oncogene tyrosine-protein kinase Yes (EC 2.7.10.2)| (p61-Yes) (c-Yes) Length = 538 Score = 65.1 bits (157), Expect = 2e-10 Identities = 51/179 (28%), Positives = 87/179 (48%), Gaps = 8/179 (4%) Frame = -2 Query: 739 LRIIHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTA-----YTLKVIGTYGYMSPEY 575 + IHRD++A+N+L+ N++ KI+DFG+AR+ ++ TA + +K + +PE Sbjct: 385 MNYIHRDLRAANILVGENLVCKIADFGLARLIEDNEYTARQGAKFPIK------WTAPEA 438 Query: 574 AMDGVFSMKSDIYSFGVMVLEIVTGKKNRGFYDAELDLNLLGYAWTLWKEGRSTELLDEA 395 A+ G F++KSD++SFG++ E+ T K R Y + + E+L++ Sbjct: 439 ALYGRFTIKSDVWSFGILQTELTT--KGRVPYPGMV----------------NREVLEQV 480 Query: 394 MMG--SSCDHSQVRRCIQVALLCVDMNPRNRPLMSSIVMMLATENATLPEPN-EPGGNV 227 G C ++ LC +P RP I L + T EP +PG N+ Sbjct: 481 ERGYRMPCPQGCPESLHELMNLCWKKDPDERPTFEYIQSFL-EDYFTAAEPQYQPGENL 538
>PKN2_CLOPE (Q8XJL8) Probable serine/threonine protein kinase CPE1738 (EC| 2.7.11.1) Length = 685 Score = 65.1 bits (157), Expect = 2e-10 Identities = 32/78 (41%), Positives = 49/78 (62%) Frame = -2 Query: 733 IIHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTAYTLKVIGTYGYMSPEYAMDGVFS 554 IIHRD+K N+L+ + K++DFGIA+ T A+T V+G+ Y SPE A Sbjct: 129 IIHRDVKPQNILVTEEGVVKVTDFGIAKSMDSS-TIAHTNSVMGSAHYFSPEQAKGTYTD 187 Query: 553 MKSDIYSFGVMVLEIVTG 500 ++D+YS G+++ E+VTG Sbjct: 188 YRTDLYSLGIVLYEMVTG 205
>PKNB_BIFLO (Q8G6P9) Probable serine/threonine-protein kinase pknB (EC| 2.7.11.1) Length = 690 Score = 65.1 bits (157), Expect = 2e-10 Identities = 32/80 (40%), Positives = 48/80 (60%), Gaps = 1/80 (1%) Frame = -2 Query: 733 IIHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTT-AYTLKVIGTYGYMSPEYAMDGVF 557 IIHRD+K N+++ + K+ DFGIAR T + V+GT Y+SPE A Sbjct: 142 IIHRDIKPGNIMISEQGVVKVMDFGIARALDDSAATMTQSQGVVGTAQYLSPEQARGETV 201 Query: 556 SMKSDIYSFGVMVLEIVTGK 497 M+SD+YS G ++ E++TG+ Sbjct: 202 DMRSDLYSAGCVLYEMLTGR 221
>PKNB_MYCTU (P0A5S4) Probable serine/threonine-protein kinase pknB (EC| 2.7.11.1) Length = 626 Score = 64.7 bits (156), Expect = 3e-10 Identities = 32/80 (40%), Positives = 47/80 (58%), Gaps = 1/80 (1%) Frame = -2 Query: 733 IIHRDMKASNVLLDRNMIPKISDFGIARMFGGD-QTTAYTLKVIGTYGYMSPEYAMDGVF 557 IIHRD+K +N+++ K+ DFGIAR + T VIGT Y+SPE A Sbjct: 134 IIHRDVKPANIMISATNAVKVMDFGIARAIADSGNSVTQTAAVIGTAQYLSPEQARGDSV 193 Query: 556 SMKSDIYSFGVMVLEIVTGK 497 +SD+YS G ++ E++TG+ Sbjct: 194 DARSDVYSLGCVLYEVLTGE 213
>PKNB_MYCBO (P0A5S5) Probable serine/threonine-protein kinase pknB (EC| 2.7.11.1) Length = 626 Score = 64.7 bits (156), Expect = 3e-10 Identities = 32/80 (40%), Positives = 47/80 (58%), Gaps = 1/80 (1%) Frame = -2 Query: 733 IIHRDMKASNVLLDRNMIPKISDFGIARMFGGD-QTTAYTLKVIGTYGYMSPEYAMDGVF 557 IIHRD+K +N+++ K+ DFGIAR + T VIGT Y+SPE A Sbjct: 134 IIHRDVKPANIMISATNAVKVMDFGIARAIADSGNSVTQTAAVIGTAQYLSPEQARGDSV 193 Query: 556 SMKSDIYSFGVMVLEIVTGK 497 +SD+YS G ++ E++TG+ Sbjct: 194 DARSDVYSLGCVLYEVLTGE 213
>SRC_RAT (Q9WUD9) Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2)| (p60-Src) (c-Src) (pp60c-src) Length = 535 Score = 64.3 bits (155), Expect = 4e-10 Identities = 29/84 (34%), Positives = 57/84 (67%), Gaps = 5/84 (5%) Frame = -2 Query: 739 LRIIHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTA-----YTLKVIGTYGYMSPEY 575 + +HRD++A+N+L+ N++ K++DFG+AR+ ++ TA + +K + +PE Sbjct: 382 MNYVHRDLRAANILVGENLVCKVADFGLARLIEDNEYTARQGAKFPIK------WTAPEA 435 Query: 574 AMDGVFSMKSDIYSFGVMVLEIVT 503 A+ G F++KSD++SFG+++ E+ T Sbjct: 436 ALYGRFTIKSDVWSFGILLTELTT 459
>SRC_HUMAN (P12931) Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2)| (p60-Src) (c-Src) (pp60c-src) Length = 535 Score = 64.3 bits (155), Expect = 4e-10 Identities = 29/84 (34%), Positives = 57/84 (67%), Gaps = 5/84 (5%) Frame = -2 Query: 739 LRIIHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTA-----YTLKVIGTYGYMSPEY 575 + +HRD++A+N+L+ N++ K++DFG+AR+ ++ TA + +K + +PE Sbjct: 382 MNYVHRDLRAANILVGENLVCKVADFGLARLIEDNEYTARQGAKFPIK------WTAPEA 435 Query: 574 AMDGVFSMKSDIYSFGVMVLEIVT 503 A+ G F++KSD++SFG+++ E+ T Sbjct: 436 ALYGRFTIKSDVWSFGILLTELTT 459
>STK_HYDAT (P17713) Tyrosine-protein kinase STK (EC 2.7.10.2) (P57-STK)| Length = 509 Score = 64.3 bits (155), Expect = 4e-10 Identities = 32/76 (42%), Positives = 51/76 (67%) Frame = -2 Query: 730 IHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTAYTLKVIGTYGYMSPEYAMDGVFSM 551 IHRD+ A N+L+ N I K++DFG+AR+ D+ TA+ + +PE A+ F++ Sbjct: 357 IHRDLAARNILVGENYICKVADFGLARLIEDDEYTAHEGAKF-PIKWTAPEAALYNRFTI 415 Query: 550 KSDIYSFGVMVLEIVT 503 KSD++SFG+++ EIVT Sbjct: 416 KSDVWSFGILMAEIVT 431
>SRC_MOUSE (P05480) Neuronal proto-oncogene tyrosine-protein kinase Src (EC| 2.7.10.2) (p60-Src) (c-Src) (pp60c-src) Length = 540 Score = 64.3 bits (155), Expect = 4e-10 Identities = 29/84 (34%), Positives = 57/84 (67%), Gaps = 5/84 (5%) Frame = -2 Query: 739 LRIIHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTA-----YTLKVIGTYGYMSPEY 575 + +HRD++A+N+L+ N++ K++DFG+AR+ ++ TA + +K + +PE Sbjct: 387 MNYVHRDLRAANILVGENLVCKVADFGLARLIEDNEYTARQGAKFPIK------WTAPEA 440 Query: 574 AMDGVFSMKSDIYSFGVMVLEIVT 503 A+ G F++KSD++SFG+++ E+ T Sbjct: 441 ALYGRFTIKSDVWSFGILLTELTT 464
>SRC2_XENLA (P13116) Tyrosine-protein kinase Src-2 (EC 2.7.10.2) (p60-Src-2)| Length = 531 Score = 64.3 bits (155), Expect = 4e-10 Identities = 29/84 (34%), Positives = 57/84 (67%), Gaps = 5/84 (5%) Frame = -2 Query: 739 LRIIHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTA-----YTLKVIGTYGYMSPEY 575 + +HRD++A+N+L+ N++ K++DFG+AR+ ++ TA + +K + +PE Sbjct: 378 MNYVHRDLRAANILVGENLVCKVADFGLARLIEDNEYTARQGAKFPIK------WTAPEA 431 Query: 574 AMDGVFSMKSDIYSFGVMVLEIVT 503 A+ G F++KSD++SFG+++ E+ T Sbjct: 432 ALYGRFTIKSDVWSFGILLTELTT 455
>SRC1_XENLA (P13115) Tyrosine-protein kinase Src-1 (EC 2.7.10.2) (p60-Src-1)| Length = 531 Score = 64.3 bits (155), Expect = 4e-10 Identities = 29/84 (34%), Positives = 57/84 (67%), Gaps = 5/84 (5%) Frame = -2 Query: 739 LRIIHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTA-----YTLKVIGTYGYMSPEY 575 + +HRD++A+N+L+ N++ K++DFG+AR+ ++ TA + +K + +PE Sbjct: 378 MNYVHRDLRAANILVGENLVCKVADFGLARLIEDNEYTARQGAKFPIK------WTAPEA 431 Query: 574 AMDGVFSMKSDIYSFGVMVLEIVT 503 A+ G F++KSD++SFG+++ E+ T Sbjct: 432 ALYGRFTIKSDVWSFGILLTELTT 455
>SRC_AVISS (P14084) Tyrosine-protein kinase transforming protein Src (EC| 2.7.10.2) (p60-Src) (v-Src) (pp60v-src) Length = 567 Score = 64.3 bits (155), Expect = 4e-10 Identities = 29/84 (34%), Positives = 57/84 (67%), Gaps = 5/84 (5%) Frame = -2 Query: 739 LRIIHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTA-----YTLKVIGTYGYMSPEY 575 + +HRD++A+N+L+ N++ K++DFG+AR+ ++ TA + +K + +PE Sbjct: 379 MNYVHRDLRAANILVGENLVCKVADFGLARLIEDNEYTARQGAKFPIK------WTAPEA 432 Query: 574 AMDGVFSMKSDIYSFGVMVLEIVT 503 A+ G F++KSD++SFG+++ E+ T Sbjct: 433 ALYGRFTIKSDVWSFGILLTELTT 456
>SRC_CHICK (P00523) Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2)| (p60-Src) (c-Src) (pp60c-src) Length = 532 Score = 64.3 bits (155), Expect = 4e-10 Identities = 29/84 (34%), Positives = 57/84 (67%), Gaps = 5/84 (5%) Frame = -2 Query: 739 LRIIHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTA-----YTLKVIGTYGYMSPEY 575 + +HRD++A+N+L+ N++ K++DFG+AR+ ++ TA + +K + +PE Sbjct: 379 MNYVHRDLRAANILVGENLVCKVADFGLARLIEDNEYTARQGAKFPIK------WTAPEA 432 Query: 574 AMDGVFSMKSDIYSFGVMVLEIVT 503 A+ G F++KSD++SFG+++ E+ T Sbjct: 433 ALYGRFTIKSDVWSFGILLTELTT 456
>SRC_AVIST (P14085) Tyrosine-protein kinase transforming protein Src (EC| 2.7.10.2) (p60-Src) (v-Src) (pp60v-src) Length = 556 Score = 64.3 bits (155), Expect = 4e-10 Identities = 29/84 (34%), Positives = 57/84 (67%), Gaps = 5/84 (5%) Frame = -2 Query: 739 LRIIHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTA-----YTLKVIGTYGYMSPEY 575 + +HRD++A+N+L+ N++ K++DFG+AR+ ++ TA + +K + +PE Sbjct: 379 MNYVHRDLRAANILVGENLVCKVADFGLARLIEDNEYTARQGAKFPIK------WTAPEA 432 Query: 574 AMDGVFSMKSDIYSFGVMVLEIVT 503 A+ G F++KSD++SFG+++ E+ T Sbjct: 433 ALYGRFTIKSDVWSFGILLTELTT 456
>SRC_RSVSE (P63185) Tyrosine-protein kinase transforming protein Src (EC| 2.7.10.2) (p60-Src) (v-Src) (pp60v-src) Length = 525 Score = 64.3 bits (155), Expect = 4e-10 Identities = 29/84 (34%), Positives = 57/84 (67%), Gaps = 5/84 (5%) Frame = -2 Query: 739 LRIIHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTA-----YTLKVIGTYGYMSPEY 575 + +HRD++A+N+L+ N++ K++DFG+AR+ ++ TA + +K + +PE Sbjct: 379 MNYVHRDLRAANILVGENLVCKVADFGLARLIEDNEYTARQGAKFPIK------WTAPEA 432 Query: 574 AMDGVFSMKSDIYSFGVMVLEIVT 503 A+ G F++KSD++SFG+++ E+ T Sbjct: 433 ALYGRFTIKSDVWSFGILLTELTT 456
>SRC_RSVSA (P00524) Tyrosine-protein kinase transforming protein Src (EC| 2.7.10.2) (p60-Src) (v-Src) (pp60v-src) Length = 525 Score = 64.3 bits (155), Expect = 4e-10 Identities = 29/84 (34%), Positives = 57/84 (67%), Gaps = 5/84 (5%) Frame = -2 Query: 739 LRIIHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTA-----YTLKVIGTYGYMSPEY 575 + +HRD++A+N+L+ N++ K++DFG+AR+ ++ TA + +K + +PE Sbjct: 379 MNYVHRDLRAANILVGENLVCKVADFGLARLIEDNEYTARQGAKFPIK------WTAPEA 432 Query: 574 AMDGVFSMKSDIYSFGVMVLEIVT 503 A+ G F++KSD++SFG+++ E+ T Sbjct: 433 ALYGRFTIKSDVWSFGILLTELTT 456
>SRC_RSVP (P00526) Tyrosine-protein kinase transforming protein Src (EC| 2.7.10.2) (p60-Src) (v-Src) (pp60v-src) Length = 525 Score = 64.3 bits (155), Expect = 4e-10 Identities = 29/84 (34%), Positives = 57/84 (67%), Gaps = 5/84 (5%) Frame = -2 Query: 739 LRIIHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTA-----YTLKVIGTYGYMSPEY 575 + +HRD++A+N+L+ N++ K++DFG+AR+ ++ TA + +K + +PE Sbjct: 379 MNYVHRDLRAANILVGENLVCKVADFGLARLIEDNEYTARQGAKFPIK------WTAPEA 432 Query: 574 AMDGVFSMKSDIYSFGVMVLEIVT 503 A+ G F++KSD++SFG+++ E+ T Sbjct: 433 ALYGRFTIKSDVWSFGILLTELTT 456
>SRC_RSVH1 (P25020) Tyrosine-protein kinase transforming protein Src (EC| 2.7.10.2) (p60-Src) (v-Src) (pp60v-src) Length = 525 Score = 64.3 bits (155), Expect = 4e-10 Identities = 29/84 (34%), Positives = 57/84 (67%), Gaps = 5/84 (5%) Frame = -2 Query: 739 LRIIHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTA-----YTLKVIGTYGYMSPEY 575 + +HRD++A+N+L+ N++ K++DFG+AR+ ++ TA + +K + +PE Sbjct: 379 MNYVHRDLRAANILVGENLVCKVADFGLARLIEDNEYTARQGAKFPIK------WTAPEA 432 Query: 574 AMDGVFSMKSDIYSFGVMVLEIVT 503 A+ G F++KSD++SFG+++ E+ T Sbjct: 433 ALYGRFTIKSDVWSFGILLTELTT 456
>SRC_AVISR (P00525) Tyrosine-protein kinase transforming protein Src (EC| 2.7.10.2) (p60-Src) (v-Src) (pp60v-src) Length = 525 Score = 64.3 bits (155), Expect = 4e-10 Identities = 29/84 (34%), Positives = 57/84 (67%), Gaps = 5/84 (5%) Frame = -2 Query: 739 LRIIHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTA-----YTLKVIGTYGYMSPEY 575 + +HRD++A+N+L+ N++ K++DFG+AR+ ++ TA + +K + +PE Sbjct: 379 MNYVHRDLRAANILVGENLVCKVADFGLARLIEDNEYTARQGAKFPIK------WTAPEA 432 Query: 574 AMDGVFSMKSDIYSFGVMVLEIVT 503 A+ G F++KSD++SFG+++ E+ T Sbjct: 433 ALYGRFTIKSDVWSFGILLTELTT 456
>SRC_AVIS2 (P15054) Tyrosine-protein kinase transforming protein Src (EC| 2.7.10.2) (p60-Src) (v-Src) (pp60v-src) Length = 586 Score = 64.3 bits (155), Expect = 4e-10 Identities = 29/84 (34%), Positives = 57/84 (67%), Gaps = 5/84 (5%) Frame = -2 Query: 739 LRIIHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTA-----YTLKVIGTYGYMSPEY 575 + +HRD++A+N+L+ N++ K++DFG+AR+ ++ TA + +K + +PE Sbjct: 379 MNYVHRDLRAANILVGENLVCKVADFGLARLIEDNEYTARQGAKFPIK------WTAPEA 432 Query: 574 AMDGVFSMKSDIYSFGVMVLEIVT 503 A+ G F++KSD++SFG+++ E+ T Sbjct: 433 ALYGRFTIKSDVWSFGILLTELTT 456
>NEK9_XENLA (Q7ZZC8) Serine/threonine-protein kinase Nek9 (EC 2.7.11.1)| (NimA-related protein kinase 9) (XNek9) (Nercc1 kinase) Length = 944 Score = 63.9 bits (154), Expect = 5e-10 Identities = 44/150 (29%), Positives = 73/150 (48%), Gaps = 1/150 (0%) Frame = -2 Query: 733 IIHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTAYTLKVIGTYGYMSPEYAMDGVFS 554 I+HRD+K N+ L + + K+ D+G+A+ + + A T +GT YMSPE +S Sbjct: 154 ILHRDIKTLNIFLTKANLIKLGDYGLAKQLSSEYSMAETC--VGTLYYMSPEICQGVKYS 211 Query: 553 MKSDIYSFGVMVLEIVTGKKNRGFYDAELDLNL-LGYAWTLWKEGRSTELLDEAMMGSSC 377 KSDI++ G ++ E++T + +DA LNL + W G LD + Sbjct: 212 FKSDIWAVGCVLYELLTLTRT---FDATNPLNLCVKIVQGNWAVG-----LDNTV----- 258 Query: 376 DHSQVRRCIQVALLCVDMNPRNRPLMSSIV 287 + I+V C++ +P RP I+ Sbjct: 259 ---YTQELIEVVHACLEQDPEKRPTADEIL 285
>FGR_MOUSE (P14234) Proto-oncogene tyrosine-protein kinase FGR (EC 2.7.10.2)| (P55-FGR) (C-FGR) Length = 517 Score = 63.9 bits (154), Expect = 5e-10 Identities = 31/84 (36%), Positives = 56/84 (66%), Gaps = 5/84 (5%) Frame = -2 Query: 739 LRIIHRDMKASNVLLDRNMIPKISDFGIARM-----FGGDQTTAYTLKVIGTYGYMSPEY 575 + IHRD++A+N+L+ +I KI+DFG+AR+ + Q T + +K + +PE Sbjct: 364 MNYIHRDLRAANILVGEYLICKIADFGLARLIEDNEYNPQQGTKFPIK------WTAPEA 417 Query: 574 AMDGVFSMKSDIYSFGVMVLEIVT 503 A+ G F++KSD++SFG+++ E++T Sbjct: 418 ALFGRFTVKSDVWSFGILLTELIT 441
>M3K12_HUMAN (Q12852) Mitogen-activated protein kinase kinase kinase 12 (EC| 2.7.11.25) (Mixed lineage kinase) (Leucine-zipper protein kinase) (ZPK) (Dual leucine zipper bearing kinase) (DLK) (MAPK-upstream kinase) (MUK) Length = 859 Score = 63.9 bits (154), Expect = 5e-10 Identities = 51/167 (30%), Positives = 82/167 (49%), Gaps = 2/167 (1%) Frame = -2 Query: 736 RIIHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTAYTLKVIGTYGYMSPEYAMDGVF 557 +IIHRD+K+ N+L+ + + KISDFG ++ T + GT +M+PE + Sbjct: 231 KIIHRDLKSPNMLITYDDVVKISDFGTSKELSDKSTK---MSFAGTVAWMAPEVIRNEPV 287 Query: 556 SMKSDIYSFGVMVLEIVTGKKNRGFYDAELDLNLLGYAWTLWKEGRSTELLDEAMMGSSC 377 S K DI+SFGV++ E++TG E+ + + +W G ++ L + SSC Sbjct: 288 SEKVDIWSFGVVLWELLTG---------EIPYKDVDSSAIIWGVGSNSLHLP---VPSSC 335 Query: 376 DHSQVRRCIQVAL-LCVDMNPRNRPLMSSIVMMLATENA-TLPEPNE 242 ++ L C + PRNRP I++ L +A L P E Sbjct: 336 PDG-----FKILLRQCWNSKPRNRPSFRQILLHLDIASADVLSTPQE 377
>SRC_RSVPA (P31693) Tyrosine-protein kinase transforming protein Src (EC| 2.7.10.2) (p60-Src) (v-Src) (pp60v-src) Length = 522 Score = 63.9 bits (154), Expect = 5e-10 Identities = 29/84 (34%), Positives = 57/84 (67%), Gaps = 5/84 (5%) Frame = -2 Query: 739 LRIIHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTA-----YTLKVIGTYGYMSPEY 575 + +HRD++A+N+L+ N++ K++DFG+AR+ ++ TA + +K + +PE Sbjct: 376 MNYVHRDLRAANILVGENLVCKVADFGLARLIEDNEYTARPGARFPVK------WTAPEA 429 Query: 574 AMDGVFSMKSDIYSFGVMVLEIVT 503 A+ G F++KSD++SFG+++ E+ T Sbjct: 430 ALYGRFTIKSDVWSFGILLTELTT 453
>M3K12_RAT (Q63796) Mitogen-activated protein kinase kinase kinase 12 (EC| 2.7.11.25) (Mixed lineage kinase) (Leucine-zipper protein kinase) (ZPK) (Dual leucine zipper bearing kinase) (DLK) (MAPK-upstream kinase) (MUK) Length = 888 Score = 63.9 bits (154), Expect = 5e-10 Identities = 51/167 (30%), Positives = 82/167 (49%), Gaps = 2/167 (1%) Frame = -2 Query: 736 RIIHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTAYTLKVIGTYGYMSPEYAMDGVF 557 +IIHRD+K+ N+L+ + + KISDFG ++ T + GT +M+PE + Sbjct: 264 KIIHRDLKSPNMLITYDDVVKISDFGTSKELSDKSTK---MSFAGTVAWMAPEVIRNEPV 320 Query: 556 SMKSDIYSFGVMVLEIVTGKKNRGFYDAELDLNLLGYAWTLWKEGRSTELLDEAMMGSSC 377 S K DI+SFGV++ E++TG E+ + + +W G ++ L + SSC Sbjct: 321 SEKVDIWSFGVVLWELLTG---------EIPYKDVDSSAIIWGVGSNSLHLP---VPSSC 368 Query: 376 DHSQVRRCIQVAL-LCVDMNPRNRPLMSSIVMMLATENA-TLPEPNE 242 ++ L C + PRNRP I++ L +A L P E Sbjct: 369 PDG-----FKILLRQCWNRKPRNRPSFRQILLHLDIASADVLSTPQE 410
>M3K12_MOUSE (Q60700) Mitogen-activated protein kinase kinase kinase 12 (EC| 2.7.11.25) (Mixed lineage kinase) (Leucine-zipper protein kinase) (ZPK) (Dual leucine zipper bearing kinase) (DLK) (MAPK-upstream kinase) (MUK) Length = 888 Score = 63.9 bits (154), Expect = 5e-10 Identities = 51/167 (30%), Positives = 82/167 (49%), Gaps = 2/167 (1%) Frame = -2 Query: 736 RIIHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTAYTLKVIGTYGYMSPEYAMDGVF 557 +IIHRD+K+ N+L+ + + KISDFG ++ T + GT +M+PE + Sbjct: 264 KIIHRDLKSPNMLITYDDVVKISDFGTSKELSDKSTK---MSFAGTVAWMAPEVIRNEPV 320 Query: 556 SMKSDIYSFGVMVLEIVTGKKNRGFYDAELDLNLLGYAWTLWKEGRSTELLDEAMMGSSC 377 S K DI+SFGV++ E++TG E+ + + +W G ++ L + SSC Sbjct: 321 SEKVDIWSFGVVLWELLTG---------EIPYKDVDSSAIIWGVGSNSLHLP---VPSSC 368 Query: 376 DHSQVRRCIQVAL-LCVDMNPRNRPLMSSIVMMLATENA-TLPEPNE 242 ++ L C + PRNRP I++ L +A L P E Sbjct: 369 PDG-----FKILLRQCWNSKPRNRPSFRQILLHLDIASADVLSTPQE 410
>M3K9_HUMAN (P80192) Mitogen-activated protein kinase kinase kinase 9 (EC| 2.7.11.25) (Mixed lineage kinase 1) Length = 1104 Score = 63.9 bits (154), Expect = 5e-10 Identities = 36/87 (41%), Positives = 57/87 (65%), Gaps = 8/87 (9%) Frame = -2 Query: 733 IIHRDMKASNVLLDR--------NMIPKISDFGIARMFGGDQTTAYTLKVIGTYGYMSPE 578 IIHRD+K+SN+L+ + N I KI+DFG+AR + +TT + GTY +M+PE Sbjct: 264 IIHRDLKSSNILILQKVENGDLSNKILKITDFGLAREW--HRTTK--MSAAGTYAWMAPE 319 Query: 577 YAMDGVFSMKSDIYSFGVMVLEIVTGK 497 +FS SD++S+GV++ E++TG+ Sbjct: 320 VIRASMFSKGSDVWSYGVLLWELLTGE 346
>FYN_XENLA (P13406) Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2)| (p59-Fyn) Length = 536 Score = 63.5 bits (153), Expect = 6e-10 Identities = 31/84 (36%), Positives = 57/84 (67%), Gaps = 5/84 (5%) Frame = -2 Query: 739 LRIIHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTA-----YTLKVIGTYGYMSPEY 575 + IHRD++++N+L+ +I KI+DFG+AR+ ++ TA + +K + +PE Sbjct: 383 MNYIHRDLRSANILVGNGLICKIADFGLARLIEDNEYTARQGAKFPIK------WTAPEA 436 Query: 574 AMDGVFSMKSDIYSFGVMVLEIVT 503 A+ G F++KSD++SFG+++ E+VT Sbjct: 437 ALYGRFTIKSDVWSFGILLTELVT 460
>FYN_HUMAN (P06241) Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2)| (p59-Fyn) (Protooncogene Syn) (SLK) Length = 536 Score = 63.5 bits (153), Expect = 6e-10 Identities = 31/84 (36%), Positives = 57/84 (67%), Gaps = 5/84 (5%) Frame = -2 Query: 739 LRIIHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTA-----YTLKVIGTYGYMSPEY 575 + IHRD++++N+L+ +I KI+DFG+AR+ ++ TA + +K + +PE Sbjct: 383 MNYIHRDLRSANILVGNGLICKIADFGLARLIEDNEYTARQGAKFPIK------WTAPEA 436 Query: 574 AMDGVFSMKSDIYSFGVMVLEIVT 503 A+ G F++KSD++SFG+++ E+VT Sbjct: 437 ALYGRFTIKSDVWSFGILLTELVT 460
>PLK4_MOUSE (Q64702) Serine/threonine-protein kinase PLK4 (EC 2.7.11.21)| (Polo-like kinase 4) (PLK-4) (Serine/threonine-protein kinase Sak) (Serine/threonine-protein kinase 18) Length = 925 Score = 63.5 bits (153), Expect = 6e-10 Identities = 34/79 (43%), Positives = 46/79 (58%) Frame = -2 Query: 733 IIHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTAYTLKVIGTYGYMSPEYAMDGVFS 554 I+HRD+ SN+LL RNM KI+DFG+A YTL GT Y+SPE A Sbjct: 132 ILHRDLTLSNILLTRNMNIKIADFGLATQLNMPHEKHYTL--CGTPNYISPEIATRSAHG 189 Query: 553 MKSDIYSFGVMVLEIVTGK 497 ++SDI+S G M ++ G+ Sbjct: 190 LESDIWSLGCMFYTLLIGR 208
>FYN_MOUSE (P39688) Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2)| (p59-Fyn) Length = 533 Score = 63.5 bits (153), Expect = 6e-10 Identities = 31/84 (36%), Positives = 57/84 (67%), Gaps = 5/84 (5%) Frame = -2 Query: 739 LRIIHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTA-----YTLKVIGTYGYMSPEY 575 + IHRD++++N+L+ +I KI+DFG+AR+ ++ TA + +K + +PE Sbjct: 380 MNYIHRDLRSANILVGNGLICKIADFGLARLIEDNEYTARQGAKFPIK------WTAPEA 433 Query: 574 AMDGVFSMKSDIYSFGVMVLEIVT 503 A+ G F++KSD++SFG+++ E+VT Sbjct: 434 ALYGRFTIKSDVWSFGILLTELVT 457
>FYN_CHICK (Q05876) Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2)| (p59-Fyn) Length = 533 Score = 63.5 bits (153), Expect = 6e-10 Identities = 31/84 (36%), Positives = 57/84 (67%), Gaps = 5/84 (5%) Frame = -2 Query: 739 LRIIHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTA-----YTLKVIGTYGYMSPEY 575 + IHRD++++N+L+ +I KI+DFG+AR+ ++ TA + +K + +PE Sbjct: 380 MNYIHRDLRSANILVGNGLICKIADFGLARLIEDNEYTARQGAKFPIK------WTAPEA 433 Query: 574 AMDGVFSMKSDIYSFGVMVLEIVT 503 A+ G F++KSD++SFG+++ E+VT Sbjct: 434 ALYGRFTIKSDVWSFGILLTELVT 457
>BYR1_SCHPO (P10506) Protein kinase byr1 (EC 2.7.12.2) (MAPK kinase) (MAPKK)| Length = 340 Score = 63.5 bits (153), Expect = 6e-10 Identities = 33/96 (34%), Positives = 56/96 (58%) Frame = -2 Query: 739 LRIIHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTAYTLKVIGTYGYMSPEYAMDGV 560 L IIHRD+K SNV+++ K+ DFG++ G+ + +GT YMSPE G Sbjct: 180 LHIIHRDLKPSNVVVNSRGEIKLCDFGVS----GELVNSVAQTFVGTSTYMSPERIRGGK 235 Query: 559 FSMKSDIYSFGVMVLEIVTGKKNRGFYDAELDLNLL 452 +++KSDI+S G+ ++E+ T + F + + + +L Sbjct: 236 YTVKSDIWSLGISIIELATQELPWSFSNIDDSIGIL 271
>RIPK3_RAT (Q9Z2P5) Receptor-interacting serine/threonine-protein kinase 3 (EC| 2.7.11.1) (RIP-like protein kinase 3) (Receptor-interacting protein 3) (RIP-3) (Homocysteine respondent protein HCYP2) Length = 478 Score = 63.5 bits (153), Expect = 6e-10 Identities = 34/83 (40%), Positives = 53/83 (63%), Gaps = 3/83 (3%) Frame = -2 Query: 733 IIHRDMKASNVLLDRNMIPKISDFGIARMFGGDQ--TTAYTLKVIGTYGYMSPEYA-MDG 563 ++HRD+K SNVLLD + K++DFG++ GG Q + + + GT Y++PE DG Sbjct: 139 LLHRDLKPSNVLLDLELHAKLADFGLSTFQGGSQSGSGSGSRDSGGTLAYLAPELLDNDG 198 Query: 562 VFSMKSDIYSFGVMVLEIVTGKK 494 S SD+YSFGV+V ++ G++ Sbjct: 199 KASKASDVYSFGVLVWTVLAGRE 221
>PKN1_CORGL (Q8NU98) Probable serine/threonine protein kinase pknB (EC| 2.7.11.1) Length = 646 Score = 63.5 bits (153), Expect = 6e-10 Identities = 37/81 (45%), Positives = 50/81 (61%), Gaps = 2/81 (2%) Frame = -2 Query: 733 IIHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTAYTLK--VIGTYGYMSPEYAMDGV 560 IIHRD+K +N+++ K+ DFGIAR D T+A T VIGT Y+SPE A Sbjct: 132 IIHRDVKPANIMITNTGGVKVMDFGIARAVN-DSTSAMTQTSAVIGTAQYLSPEQARGKP 190 Query: 559 FSMKSDIYSFGVMVLEIVTGK 497 +SDIY+ G ++ E+VTGK Sbjct: 191 ADARSDIYATGCVMYELVTGK 211
>YR831_MIMIV (Q7T6Y2) Putative serine/threonine-protein kinase/receptor R831| precursor (EC 2.7.11.1) Length = 1624 Score = 63.2 bits (152), Expect = 8e-10 Identities = 47/157 (29%), Positives = 79/157 (50%), Gaps = 2/157 (1%) Frame = -2 Query: 733 IIHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTAYTLKVIGTYGYMSPEYAMDGVFS 554 I+HRD+K +N+L+D + KI+DFG AR+ D T T+ GT + +PE + Sbjct: 1483 IVHRDIKPANILVDEHFNVKIADFGFARI-KEDNT---TMTRCGTPCWTAPEVIRGEKYC 1538 Query: 553 MKSDIYSFGVMVLEIVTGKKNRGFYDAELDLNLLGYAWTLWKEGRSTELLDEAMMGSSCD 374 K+D++SFGV++ E++TGK + + N + + + + GR ++ S C Sbjct: 1539 EKADVFSFGVVMWEVLTGK------EPFAECNFMKVSLDILEGGR-------PIIPSDCP 1585 Query: 373 HSQVRRCIQVALLCVDMNPRNRPLMSSIV--MMLATE 269 H + + C RP M+ +V +ML TE Sbjct: 1586 HEFAK----LIKKCWHAKAHKRPTMTEVVQQLMLITE 1618 Score = 63.2 bits (152), Expect = 8e-10 Identities = 50/195 (25%), Positives = 96/195 (49%), Gaps = 10/195 (5%) Frame = -2 Query: 733 IIHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTAYTLKVIGTYGYMSPEYAMDG--V 560 I+HRD+K+ N+LLD K+SDFG+ ++ +IGT +++PE D V Sbjct: 904 IVHRDLKSLNLLLDSKWNVKVSDFGLTKVKSELDKKKTNDNIIGTIHWIAPEILNDSTEV 963 Query: 559 FSMKSDIYSFGVMVLEIVTGKK-NRGFYDAELDLNLLGYAWTLWKEGRSTELLDEAMMGS 383 + +D+YSFG+++ E++T ++ +G A + ++++ ++G + DEA+ Sbjct: 964 DYILADVYSFGIILWELLTREQPYKGMTPAAIAVSVI-------RDGMRPPISDEAVTAH 1016 Query: 382 SCDHSQVRRCIQVALLCVDMNPRNRPLMSSIVMMLA-----TENAT--LPEPNEPGGNVG 224 S ++ I + C + RP I+ L+ + N T + G +G Sbjct: 1017 SIEY------IDLIKQCWHSDTIIRPTFLEIMTRLSNILGDSSNMTSGTSSSSLSSGGIG 1070 Query: 223 KSTSDGELSQTQSEL 179 KS +D + S ++S + Sbjct: 1071 KSITDSKSSNSRSSV 1085
>PKN1_COREF (Q8FUI5) Probable serine/threonine protein kinase CE0033 (EC| 2.7.11.1) Length = 660 Score = 63.2 bits (152), Expect = 8e-10 Identities = 35/81 (43%), Positives = 51/81 (62%), Gaps = 2/81 (2%) Frame = -2 Query: 733 IIHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTAYT--LKVIGTYGYMSPEYAMDGV 560 IIHRD+K +N++++ K+ DFGIAR D T+A T VIGT Y+SPE A Sbjct: 132 IIHRDVKPANIMINNTGGVKVMDFGIARALD-DSTSAMTQTAAVIGTAQYLSPEQARGKP 190 Query: 559 FSMKSDIYSFGVMVLEIVTGK 497 +SD+Y+ G ++ E+VTG+ Sbjct: 191 ADARSDVYAAGCVLYELVTGR 211
>NEK6_RAT (P59895) Serine/threonine-protein kinase Nek6 (EC 2.7.11.1)| (NimA-related protein kinase 6) Length = 313 Score = 63.2 bits (152), Expect = 8e-10 Identities = 41/144 (28%), Positives = 69/144 (47%) Frame = -2 Query: 736 RIIHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTAYTLKVIGTYGYMSPEYAMDGVF 557 R++HRD+K +NV + I K+ D G+ R F + T A++L +GT YMSPE + + Sbjct: 167 RVMHRDIKPANVFITATGIVKLGDLGLGRFFSSETTAAHSL--VGTPYYMSPERIHENGY 224 Query: 556 SMKSDIYSFGVMVLEIVTGKKNRGFYDAELDLNLLGYAWTLWKEGRSTELLDEAMMGSSC 377 + KSDI+S G ++ E+ A L G L+ + E D + Sbjct: 225 NFKSDIWSLGCLLYEM-----------AALQSPFYGDKMNLFSLCQKIEQCDYPPLPGEH 273 Query: 376 DHSQVRRCIQVALLCVDMNPRNRP 305 ++R + +C+ +P +RP Sbjct: 274 YSEKLRELVS---MCIYPDPNHRP 294
>NEK6_MOUSE (Q9ES70) Serine/threonine-protein kinase Nek6 (EC 2.7.11.1)| (NimA-related protein kinase 6) Length = 313 Score = 62.8 bits (151), Expect = 1e-09 Identities = 30/76 (39%), Positives = 48/76 (63%) Frame = -2 Query: 736 RIIHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTAYTLKVIGTYGYMSPEYAMDGVF 557 R++HRD+K +NV + I K+ D G+ R F + T A++L +GT YMSPE + + Sbjct: 167 RVMHRDIKPANVFITATGIVKLGDLGLGRFFSSETTAAHSL--VGTPYYMSPERIHENGY 224 Query: 556 SMKSDIYSFGVMVLEI 509 + KSDI+S G ++ E+ Sbjct: 225 NFKSDIWSLGCLLYEM 240
>NEK8_HUMAN (Q86SG6) Serine/threonine-protein kinase Nek8 (EC 2.7.11.1) (Never| in mitosis A-related kinase 8) (NimA-related protein kinase 8) (NIMA-related kinase 12a) Length = 692 Score = 62.8 bits (151), Expect = 1e-09 Identities = 48/150 (32%), Positives = 79/150 (52%), Gaps = 1/150 (0%) Frame = -2 Query: 733 IIHRDMKASNVLLDRN-MIPKISDFGIARMFGGDQTTAYTLKVIGTYGYMSPEYAMDGVF 557 I+HRD+K N+LLD++ M+ KI DFGI+++ ++ AYT V+GT Y+SPE + Sbjct: 124 ILHRDLKTQNILLDKHRMVVKIGDFGISKILSS-KSKAYT--VVGTPCYISPELCEGKPY 180 Query: 556 SMKSDIYSFGVMVLEIVTGKKNRGFYDAELDLNLLGYAWTLWKEGRSTELLDEAMMGSSC 377 + KSDI++ G ++ E+ + K R F A L +L +++ S Sbjct: 181 NQKSDIWALGCVLYELASLK--RAFEAANLPALVL-------------KIMSGTFAPISD 225 Query: 376 DHSQVRRCIQVALLCVDMNPRNRPLMSSIV 287 +S R Q+ L + + P RP +S I+ Sbjct: 226 RYSPELR--QLVLSLLSLEPAQRPPLSHIM 253
>HCK_MOUSE (P08103) Tyrosine-protein kinase HCK (EC 2.7.10.2)| (p56-HCK/p59-HCK) (Hemopoietic cell kinase) (B-cell/myeloid kinase) (BMK) Length = 523 Score = 62.8 bits (151), Expect = 1e-09 Identities = 31/81 (38%), Positives = 56/81 (69%), Gaps = 5/81 (6%) Frame = -2 Query: 730 IHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTA-----YTLKVIGTYGYMSPEYAMD 566 IHRD++A+N+L+ +++ KI+DFG+AR+ ++ TA + +K + +PE Sbjct: 375 IHRDLRAANILVSASLVCKIADFGLARIIEDNEYTAREGAKFPIK------WTAPEAINF 428 Query: 565 GVFSMKSDIYSFGVMVLEIVT 503 G F++KSD++SFG++++EIVT Sbjct: 429 GSFTIKSDVWSFGILLMEIVT 449
>M3KL4_HUMAN (Q5TCX8) Mitogen-activated protein kinase kinase kinase (EC| 2.7.11.25) (Mixed lineage kinase 4) Length = 1036 Score = 62.8 bits (151), Expect = 1e-09 Identities = 36/87 (41%), Positives = 55/87 (63%), Gaps = 8/87 (9%) Frame = -2 Query: 733 IIHRDMKASNVLLDR--------NMIPKISDFGIARMFGGDQTTAYTLKVIGTYGYMSPE 578 I+HRD+K+SN+LL N KI+DFG+AR + +TT + GTY +M+PE Sbjct: 259 ILHRDLKSSNILLLEKIEHDDICNKTLKITDFGLAREW--HRTTK--MSTAGTYAWMAPE 314 Query: 577 YAMDGVFSMKSDIYSFGVMVLEIVTGK 497 +FS SDI+S+GV++ E++TG+ Sbjct: 315 VIKSSLFSKGSDIWSYGVLLWELLTGE 341
>BLK_HUMAN (P51451) Tyrosine-protein kinase BLK (EC 2.7.10.2) (B lymphocyte| kinase) (p55-BLK) Length = 504 Score = 62.8 bits (151), Expect = 1e-09 Identities = 30/76 (39%), Positives = 51/76 (67%) Frame = -2 Query: 730 IHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTAYTLKVIGTYGYMSPEYAMDGVFSM 551 IHRD++A+N+L+ + KI+DFG+AR+ + T K + +PE GVF++ Sbjct: 356 IHRDLRAANILVSEALCCKIADFGLARIIDSEYTAQEGAKF--PIKWTAPEAIHFGVFTI 413 Query: 550 KSDIYSFGVMVLEIVT 503 K+D++SFGV+++E+VT Sbjct: 414 KADVWSFGVLLMEVVT 429
>SRK2_SPOLA (P42688) Tyrosine-protein kinase SRK2 (EC 2.7.10.2) (Fragment)| Length = 362 Score = 62.8 bits (151), Expect = 1e-09 Identities = 47/150 (31%), Positives = 72/150 (48%), Gaps = 3/150 (2%) Frame = -2 Query: 730 IHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTAYTLKVIGTYGYMSPEYAMDGVFSM 551 IHRD+ A N+L+ N I K++DFG+AR+ D A T + +PE A+ FS+ Sbjct: 211 IHRDLAARNILVGDNNICKVADFGLARLIVSDDYNA-TEGAKFPIKWTAPEAALFNRFSI 269 Query: 550 KSDIYSFGVMVLEIVTGKK--NRGFYDAELDLNL-LGYAWTLWKEGRSTELLDEAMMGSS 380 KSD++SFG+++ E+VT + G +AE+ NL GY Sbjct: 270 KSDVWSFGILITELVTYGRIPYPGMSNAEVLQNLDKGYR-------------------MP 310 Query: 379 CDHSQVRRCIQVALLCVDMNPRNRPLMSSI 290 C + Q+ L C NP +RP ++ Sbjct: 311 CPVTTPESLYQIMLDCWKRNPADRPTFEAL 340
>HCK_HUMAN (P08631) Tyrosine-protein kinase HCK (EC 2.7.10.2)| (p59-HCK/p60-HCK) (Hemopoietic cell kinase) Length = 525 Score = 62.8 bits (151), Expect = 1e-09 Identities = 31/81 (38%), Positives = 56/81 (69%), Gaps = 5/81 (6%) Frame = -2 Query: 730 IHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTA-----YTLKVIGTYGYMSPEYAMD 566 IHRD++A+N+L+ +++ KI+DFG+AR+ ++ TA + +K + +PE Sbjct: 377 IHRDLRAANILVSASLVCKIADFGLARVIEDNEYTAREGAKFPIK------WTAPEAINF 430 Query: 565 GVFSMKSDIYSFGVMVLEIVT 503 G F++KSD++SFG++++EIVT Sbjct: 431 GSFTIKSDVWSFGILLMEIVT 451
>HCK_RAT (P50545) Tyrosine-protein kinase HCK (EC 2.7.10.2) (p56-HCK)| (Hemopoietic cell kinase) Length = 502 Score = 62.8 bits (151), Expect = 1e-09 Identities = 31/81 (38%), Positives = 56/81 (69%), Gaps = 5/81 (6%) Frame = -2 Query: 730 IHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTA-----YTLKVIGTYGYMSPEYAMD 566 IHRD++A+N+L+ +++ KI+DFG+AR+ ++ TA + +K + +PE Sbjct: 354 IHRDLRAANILVSASLVCKIADFGLARIIEDNEYTAREGAKFPIK------WTAPEAINF 407 Query: 565 GVFSMKSDIYSFGVMVLEIVT 503 G F++KSD++SFG++++EIVT Sbjct: 408 GSFTIKSDVWSFGILLMEIVT 428
>M3LK7_DROME (P83104) Putative mitogen-activated protein kinase kinase kinase| 7-like (EC 2.7.11.25) Length = 393 Score = 62.8 bits (151), Expect = 1e-09 Identities = 51/158 (32%), Positives = 76/158 (48%), Gaps = 3/158 (1%) Frame = -2 Query: 733 IIHRDMKASNVLL-DRNMIPKISDFGIARMFGGDQTTAYTLKVIGTYGYMSPEYAMDGVF 557 I+HRD+K N+LL +++ KI DFG+A ++T GT YM+PE + Sbjct: 129 IVHRDIKPQNMLLYNQHEDLKICDFGLATDMSNNKTDMQ-----GTLRYMAPEAIKHLKY 183 Query: 556 SMKSDIYSFGVMVLEIVTGKKNRGFYDAELDLNLLGYAWTLWKEGRSTELLDEAMMGSSC 377 + K D+YSFG+M+ E++T R + L+ YA + K S E L + S C Sbjct: 184 TAKCDVYSFGIMLWELMT----RQLPYSHLENPNSQYA--IMKAISSGEKLPMEAVRSDC 237 Query: 376 DH--SQVRRCIQVALLCVDMNPRNRPLMSSIVMMLATE 269 Q+ C C+D+NP RP M I L + Sbjct: 238 PEGIKQLMEC------CMDINPEKRPSMKEIEKFLGEQ 269
>NEK8_MOUSE (Q91ZR4) Serine/threonine-protein kinase Nek8 (EC 2.7.11.1) (Never| in mitosis A-related kinase 8) (NimA-related protein kinase 8) Length = 698 Score = 62.8 bits (151), Expect = 1e-09 Identities = 48/150 (32%), Positives = 79/150 (52%), Gaps = 1/150 (0%) Frame = -2 Query: 733 IIHRDMKASNVLLDRN-MIPKISDFGIARMFGGDQTTAYTLKVIGTYGYMSPEYAMDGVF 557 I+HRD+K N+LLD++ M+ KI DFGI+++ ++ AYT V+GT Y+SPE + Sbjct: 124 ILHRDLKTQNILLDKHRMVVKIGDFGISKILSS-KSKAYT--VVGTPCYISPELCEGKPY 180 Query: 556 SMKSDIYSFGVMVLEIVTGKKNRGFYDAELDLNLLGYAWTLWKEGRSTELLDEAMMGSSC 377 + KSDI++ G ++ E+ + K R F A L +L +++ S Sbjct: 181 NQKSDIWALGCVLYELASLK--RAFEAANLPALVL-------------KIMSGTFAPISD 225 Query: 376 DHSQVRRCIQVALLCVDMNPRNRPLMSSIV 287 +S R Q+ L + + P RP +S I+ Sbjct: 226 RYSPELR--QLVLSLLSLEPAQRPPLSHIM 253
>NEK6_HUMAN (Q9HC98) Serine/threonine-protein kinase Nek6 (EC 2.7.11.1)| (NimA-related protein kinase 6) (Protein kinase SID6-1512) Length = 313 Score = 62.4 bits (150), Expect = 1e-09 Identities = 29/76 (38%), Positives = 48/76 (63%) Frame = -2 Query: 736 RIIHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTAYTLKVIGTYGYMSPEYAMDGVF 557 R++HRD+K +NV + + K+ D G+ R F + T A++L +GT YMSPE + + Sbjct: 167 RVMHRDIKPANVFITATGVVKLGDLGLGRFFSSETTAAHSL--VGTPYYMSPERIHENGY 224 Query: 556 SMKSDIYSFGVMVLEI 509 + KSDI+S G ++ E+ Sbjct: 225 NFKSDIWSLGCLLYEM 240
>FGR_HUMAN (P09769) Proto-oncogene tyrosine-protein kinase FGR (EC 2.7.10.2)| (P55-FGR) (C-FGR) Length = 529 Score = 62.0 bits (149), Expect = 2e-09 Identities = 30/84 (35%), Positives = 55/84 (65%), Gaps = 5/84 (5%) Frame = -2 Query: 739 LRIIHRDMKASNVLLDRNMIPKISDFGIARMFGGD-----QTTAYTLKVIGTYGYMSPEY 575 + IHRD++A+N+L+ + KI+DFG+AR+ D Q + + +K + +PE Sbjct: 376 MNYIHRDLRAANILVGERLACKIADFGLARLIKDDEYNPCQGSKFPIK------WTAPEA 429 Query: 574 AMDGVFSMKSDIYSFGVMVLEIVT 503 A+ G F++KSD++SFG+++ E++T Sbjct: 430 ALFGRFTIKSDVWSFGILLTELIT 453
>PKNB_LACLA (Q9CEF5) Probable serine/threonine-protein kinase pknB (EC| 2.7.11.1) Length = 627 Score = 62.0 bits (149), Expect = 2e-09 Identities = 31/79 (39%), Positives = 50/79 (63%) Frame = -2 Query: 733 IIHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTAYTLKVIGTYGYMSPEYAMDGVFS 554 IIHRD+K NVL+ + K++DFGIA+ T T + G+ Y+SPE A + Sbjct: 132 IIHRDLKPQNVLVSSSGTVKVTDFGIAKALSETSLTQ-TNTMFGSVHYLSPEQARGSNAT 190 Query: 553 MKSDIYSFGVMVLEIVTGK 497 ++SDIY+ G+++ E++TG+ Sbjct: 191 VQSDIYAIGIILFELLTGQ 209
>LYN_RAT (Q07014) Tyrosine-protein kinase Lyn (EC 2.7.10.2)| Length = 511 Score = 62.0 bits (149), Expect = 2e-09 Identities = 32/81 (39%), Positives = 55/81 (67%), Gaps = 5/81 (6%) Frame = -2 Query: 730 IHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTA-----YTLKVIGTYGYMSPEYAMD 566 IHRD++A+NVL+ +++ KI+DFG+AR+ ++ TA + +K + +PE Sbjct: 363 IHRDLRAANVLVSESLMCKIADFGLARVIEDNEYTAREGAKFPIK------WTAPEAINF 416 Query: 565 GVFSMKSDIYSFGVMVLEIVT 503 G F++KSD++SFG+++ EIVT Sbjct: 417 GCFTIKSDVWSFGILLYEIVT 437
>LYN_MOUSE (P25911) Tyrosine-protein kinase Lyn (EC 2.7.10.2)| Length = 511 Score = 62.0 bits (149), Expect = 2e-09 Identities = 32/81 (39%), Positives = 55/81 (67%), Gaps = 5/81 (6%) Frame = -2 Query: 730 IHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTA-----YTLKVIGTYGYMSPEYAMD 566 IHRD++A+NVL+ +++ KI+DFG+AR+ ++ TA + +K + +PE Sbjct: 363 IHRDLRAANVLVSESLMCKIADFGLARVIEDNEYTAREGAKFPIK------WTAPEAINF 416 Query: 565 GVFSMKSDIYSFGVMVLEIVT 503 G F++KSD++SFG+++ EIVT Sbjct: 417 GCFTIKSDVWSFGILLYEIVT 437
>LYN_HUMAN (P07948) Tyrosine-protein kinase Lyn (EC 2.7.10.2)| Length = 511 Score = 62.0 bits (149), Expect = 2e-09 Identities = 32/81 (39%), Positives = 55/81 (67%), Gaps = 5/81 (6%) Frame = -2 Query: 730 IHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTA-----YTLKVIGTYGYMSPEYAMD 566 IHRD++A+NVL+ +++ KI+DFG+AR+ ++ TA + +K + +PE Sbjct: 363 IHRDLRAANVLVSESLMCKIADFGLARVIEDNEYTAREGAKFPIK------WTAPEAINF 416 Query: 565 GVFSMKSDIYSFGVMVLEIVT 503 G F++KSD++SFG+++ EIVT Sbjct: 417 GCFTIKSDVWSFGILLYEIVT 437
>PKN2_CORGL (Q8NU97) Serine/threonine protein kinases pknA (EC 2.7.11.1)| Length = 469 Score = 62.0 bits (149), Expect = 2e-09 Identities = 34/80 (42%), Positives = 49/80 (61%) Frame = -2 Query: 733 IIHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTAYTLKVIGTYGYMSPEYAMDGVFS 554 ++HRD+K N+L+ N I KI+DFGIA+ T T V+GT Y+SPE A + Sbjct: 144 MVHRDIKPGNMLITANGIVKITDFGIAKAAAAVPLTR-TGMVVGTAQYVSPEQAQGKEVT 202 Query: 553 MKSDIYSFGVMVLEIVTGKK 494 SDIYS GV+ E++ G++ Sbjct: 203 AASDIYSLGVVGYEMMAGRR 222
>NEK8_BRARE (Q90XC2) Serine/threonine-protein kinase Nek8 (EC 2.7.11.1)| (NimA-related protein kinase 8) Length = 697 Score = 61.6 bits (148), Expect = 2e-09 Identities = 34/81 (41%), Positives = 55/81 (67%), Gaps = 1/81 (1%) Frame = -2 Query: 733 IIHRDMKASNVLLDRN-MIPKISDFGIARMFGGDQTTAYTLKVIGTYGYMSPEYAMDGVF 557 I+HRD+K N+LLD++ MI KI DFGI+++ ++ AYT V+GT Y+SPE + Sbjct: 124 ILHRDLKTQNILLDKHQMIVKIGDFGISKILVS-KSKAYT--VVGTPCYISPELCEGKPY 180 Query: 556 SMKSDIYSFGVMVLEIVTGKK 494 + KSDI++ G ++ E+ + K+ Sbjct: 181 NQKSDIWALGCVLYELASLKR 201
>SRC64_DROME (P00528) Tyrosine-protein kinase Src64B (EC 2.7.10.2) (Dsrc64)| Length = 552 Score = 61.6 bits (148), Expect = 2e-09 Identities = 31/83 (37%), Positives = 53/83 (63%), Gaps = 5/83 (6%) Frame = -2 Query: 736 RIIHRDMKASNVLLDRNMIPKISDFGIARMFGGD-----QTTAYTLKVIGTYGYMSPEYA 572 ++IHRD+ A NVL+ N + KI DFG+AR+ D Q + + +K + +PE Sbjct: 399 QLIHRDLAARNVLIGENNVAKICDFGLARVIADDEYCPKQGSRFPVK------WTAPEAI 452 Query: 571 MDGVFSMKSDIYSFGVMVLEIVT 503 + G FS+KSD++S+G++++E+ T Sbjct: 453 IYGKFSIKSDVWSYGILLMELFT 475
>PK1_STRTO (Q9KIG4) Serine/threonine-protein kinase PK-1 (EC 2.7.11.1)| (stoPK-1) Length = 641 Score = 61.6 bits (148), Expect = 2e-09 Identities = 30/79 (37%), Positives = 48/79 (60%) Frame = -2 Query: 730 IHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTAYTLKVIGTYGYMSPEYAMDGVFSM 551 +HRDMK NVL+ + K++DFG+ R D T T V+GT Y++PE G Sbjct: 138 VHRDMKPENVLIGDDGRVKVADFGLVRAV--DSVTNTTGTVLGTVSYLAPEQIEHGTADP 195 Query: 550 KSDIYSFGVMVLEIVTGKK 494 + D+Y+ G+++ E++TG+K Sbjct: 196 RVDVYACGILLYEMLTGEK 214
>PLK4_HUMAN (O00444) Serine/threonine-protein kinase PLK4 (EC 2.7.11.21)| (Polo-like kinase 4) (PLK-4) (Serine/threonine-protein kinase Sak) (Serine/threonine-protein kinase 18) Length = 970 Score = 61.6 bits (148), Expect = 2e-09 Identities = 33/79 (41%), Positives = 46/79 (58%) Frame = -2 Query: 733 IIHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTAYTLKVIGTYGYMSPEYAMDGVFS 554 I+HRD+ SN+LL RNM KI+DFG+A YTL GT Y+SPE A Sbjct: 132 ILHRDLTLSNLLLTRNMNIKIADFGLATQLKMPHEKHYTL--CGTPNYISPEIATRSAHG 189 Query: 553 MKSDIYSFGVMVLEIVTGK 497 ++SD++S G M ++ G+ Sbjct: 190 LESDVWSLGCMFYTLLIGR 208
>PKN2_COREF (Q8FUI4) Serine/threonine protein kinases drp72 (EC 2.7.11.1)| Length = 520 Score = 61.6 bits (148), Expect = 2e-09 Identities = 33/80 (41%), Positives = 50/80 (62%) Frame = -2 Query: 733 IIHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTAYTLKVIGTYGYMSPEYAMDGVFS 554 ++HRD+K N+L+ N I KI+DFGIA+ T T V+GT Y+SPE A + Sbjct: 144 LVHRDIKPGNMLITANGILKITDFGIAKAAASVPLTR-TGMVVGTAQYVSPEQAQGHQVT 202 Query: 553 MKSDIYSFGVMVLEIVTGKK 494 SD+YS GV+ E+++G++ Sbjct: 203 PASDVYSLGVVGYEMLSGRR 222
>MKK1_YEAST (P32490) MAP kinase kinase MKK1/SSP32 (EC 2.7.12.2)| Length = 508 Score = 61.6 bits (148), Expect = 2e-09 Identities = 35/113 (30%), Positives = 59/113 (52%) Frame = -2 Query: 736 RIIHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTAYTLKVIGTYGYMSPEYAMDGVF 557 ++IHRD+K N+LL+ N K+ DFG++ G+ + GT YM+PE + Sbjct: 344 KVIHRDIKPQNILLNENGQVKLCDFGVS----GEAVNSLATTFTGTSFYMAPERIQGQPY 399 Query: 556 SMKSDIYSFGVMVLEIVTGKKNRGFYDAELDLNLLGYAWTLWKEGRSTELLDE 398 S+ SD++S G+ +LE+ GK ++ N+ + +W + EL DE Sbjct: 400 SVTSDVWSLGLTILEVANGKFPCS--SEKMAANIAPFELLMWILTFTPELKDE 450
>MIL_AVIMH (P00531) Serine/threonine-protein kinase transforming protein mil| (EC 2.7.11.1) Length = 380 Score = 61.6 bits (148), Expect = 2e-09 Identities = 51/199 (25%), Positives = 91/199 (45%), Gaps = 6/199 (3%) Frame = -2 Query: 733 IIHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTAYTLKVIGTYGYMSPEYAM---DG 563 IIHRDMK++N+ L + KI DFG+A + + + G+ +M+PE Sbjct: 197 IIHRDMKSNNIFLHGGLTVKIGDFGLATVKSRWSGSQQVEQPTGSILWMAPEVIRMQDSN 256 Query: 562 VFSMKSDIYSFGVMVLEIVTGKKNRGFYDAELDLNLLGYAWTLWKEGRSTELLDEAMMGS 383 FS +SD+YS+G+++ E++TG+ + + ++ GR D + + Sbjct: 257 PFSFQSDVYSYGIVLYELMTGELPYSHINNRDQI--------IFMVGRGYASPDLSKLYK 308 Query: 382 SCDHSQVRRCIQVALLCVDMNPRNRPLMSSIVMMLATENATLPEPNEPGGNVGKSTSDGE 203 +C + R + C+ RPL I+ +A +LP+ + +S S+ Sbjct: 309 NCPKAMKR----LVADCLKKVREERPLFPQILSSIALLQHSLPK-------INRSASEPS 357 Query: 202 L---SQTQSELTVTVTDTR 155 L S T+ + T+T TR Sbjct: 358 LHRASHTEDINSCTLTSTR 376
>NEK4_MOUSE (Q9Z1J2) Serine/threonine-protein kinase Nek4 (EC 2.7.11.1)| (NimA-related protein kinase 4) (Serine/threonine-protein kinase 2) Length = 792 Score = 61.2 bits (147), Expect = 3e-09 Identities = 35/79 (44%), Positives = 46/79 (58%) Frame = -2 Query: 733 IIHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTAYTLKVIGTYGYMSPEYAMDGVFS 554 I+HRD+K NV L R I K+ D GIAR+ A TL IGT YMSPE + ++ Sbjct: 127 ILHRDLKTQNVFLTRTNIIKVGDLGIARVLENHGDMASTL--IGTPYYMSPELFSNKPYN 184 Query: 553 MKSDIYSFGVMVLEIVTGK 497 KSD+++ G V E+ T K Sbjct: 185 YKSDVWALGCCVYEMATLK 203
>FUZ7_USTMA (Q99078) Dual specificity protein kinase FUZ7 (EC 2.7.12.2)| Length = 435 Score = 61.2 bits (147), Expect = 3e-09 Identities = 35/97 (36%), Positives = 56/97 (57%), Gaps = 4/97 (4%) Frame = -2 Query: 736 RIIHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTAYTLKVIGTYGYMSPEYAMDGVF 557 RIIHRD+K SN+L++ KI DFG++ G+ + +GT YMSPE + Sbjct: 226 RIIHRDVKPSNILVNGAGQIKICDFGVS----GELINSIADTFVGTSTYMSPERIQGDQY 281 Query: 556 SMKSDIYSFGVMVLEIVTGK----KNRGFYDAELDLN 458 S+KSD++S GV ++++ G+ +N D++ D N Sbjct: 282 SVKSDVWSLGVSIIDVALGRFPFAENEEDDDSDADNN 318
>PKN6_MYXXA (P54738) Serine/threonine-protein kinase pkn6 (EC 2.7.11.1)| Length = 710 Score = 61.2 bits (147), Expect = 3e-09 Identities = 34/96 (35%), Positives = 54/96 (56%) Frame = -2 Query: 739 LRIIHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTAYTLKVIGTYGYMSPEYAMDGV 560 L +IHRD+ N+L+ R K+ DFGIA++ G T T V G YM PE Sbjct: 137 LGLIHRDVSPDNILVSRQGAVKVVDFGIAKVAGQGHRT-LTGVVKGKVAYMPPEQLQAKA 195 Query: 559 FSMKSDIYSFGVMVLEIVTGKKNRGFYDAELDLNLL 452 + D+Y+ GV++ E++TGK+ +DA D++++ Sbjct: 196 MDRRVDVYALGVVLYELLTGKRP---FDATTDVSVM 228
>CTR1_ARATH (Q05609) Serine/threonine-protein kinase CTR1 (EC 2.7.11.1)| Length = 821 Score = 61.2 bits (147), Expect = 3e-09 Identities = 49/169 (28%), Positives = 78/169 (46%), Gaps = 6/169 (3%) Frame = -2 Query: 733 IIHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTAYTLKVIGTYGYMSPEYAMDGVFS 554 I+HRD+K+ N+L+D+ K+ DFG++R+ T + GT +M+PE D + Sbjct: 672 IVHRDLKSPNLLVDKKYTVKVCDFGLSRLKA--STFLSSKSAAGTPEWMAPEVLRDEPSN 729 Query: 553 MKSDIYSFGVMVLEIVTGKKNRGFYDAELDLNLLGYAWTLWKEGRSTELLDEAMMGSSCD 374 KSD+YSFGV++ E+ T L W G A +G C Sbjct: 730 EKSDVYSFGVILWELAT----------------LQQPW-----GNLNPAQVVAAVGFKCK 768 Query: 373 HSQVRRCI--QVALL---CVDMNPRNRPLMSSIVMML-ATENATLPEPN 245 ++ R + QVA + C P RP ++I+ +L + +P PN Sbjct: 769 RLEIPRNLNPQVAAIIEGCWTNEPWKRPSFATIMDLLRPLIKSAVPPPN 817
>SRMS_HUMAN (Q9H3Y6) Tyrosine-protein kinase Srms (EC 2.7.10.2)| Length = 488 Score = 61.2 bits (147), Expect = 3e-09 Identities = 32/78 (41%), Positives = 50/78 (64%) Frame = -2 Query: 736 RIIHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTAYTLKVIGTYGYMSPEYAMDGVF 557 R++HRD+ A NVL+D + K++DFG+AR+ D + + I + +PE A VF Sbjct: 345 RVVHRDLAARNVLVDDGLACKVADFGLARLLKDDIYSPSSSSKI-PVKWTAPEAANYRVF 403 Query: 556 SMKSDIYSFGVMVLEIVT 503 S KSD++SFGV++ E+ T Sbjct: 404 SQKSDVWSFGVLLHEVFT 421
>RIPK3_HUMAN (Q9Y572) Receptor-interacting serine/threonine-protein kinase 3 (EC| 2.7.11.1) (RIP-like protein kinase 3) (Receptor-interacting protein 3) (RIP-3) Length = 518 Score = 61.2 bits (147), Expect = 3e-09 Identities = 30/82 (36%), Positives = 53/82 (64%), Gaps = 2/82 (2%) Frame = -2 Query: 733 IIHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTAYTLKVIGTYGYMSPE--YAMDGV 560 ++HRD+K SNVL D + K++DFG++ GG Q+ + + GT GY++PE ++ Sbjct: 138 LLHRDLKPSNVLPDPELHVKLADFGLSTFQGGSQSGTGSGEPGGTLGYLAPELFVNVNRK 197 Query: 559 FSMKSDIYSFGVMVLEIVTGKK 494 S SD+YSFG+++ ++ G++ Sbjct: 198 ASTASDVYSFGILMWAVLAGRE 219
>BLK_MOUSE (P16277) Tyrosine-protein kinase BLK (EC 2.7.10.2) (B lymphocyte| kinase) (p55-BLK) Length = 498 Score = 61.2 bits (147), Expect = 3e-09 Identities = 30/76 (39%), Positives = 50/76 (65%) Frame = -2 Query: 730 IHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTAYTLKVIGTYGYMSPEYAMDGVFSM 551 IHRD++A+N+L+ + KI+DFG+AR+ + T K + +PE GVF++ Sbjct: 350 IHRDLRAANILVSETLCCKIADFGLARIIDSEYTAQEGAKF--PIKWTAPEAIHFGVFTI 407 Query: 550 KSDIYSFGVMVLEIVT 503 K+D++SFGV+++ IVT Sbjct: 408 KADVWSFGVLLMVIVT 423
>BCK1_YEAST (Q01389) Serine/threonine-protein kinase BCK1/SLK1/SSP31 (EC| 2.7.11.1) Length = 1478 Score = 61.2 bits (147), Expect = 3e-09 Identities = 48/150 (32%), Positives = 79/150 (52%), Gaps = 1/150 (0%) Frame = -2 Query: 733 IIHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTAYTLKVIGTYGYMSPEYA-MDGVF 557 I+HRDMKA N+LLD++ I KISDFGI+R D + + + GT +M+PE + Sbjct: 1299 ILHRDMKADNLLLDQDGICKISDFGISRK-SKDIYSNSDMTMRGTVFWMAPEMVDTKQGY 1357 Query: 556 SMKSDIYSFGVMVLEIVTGKKNRGFYDAELDLNLLGYAWTLWKEGRSTELLDEAMMGSSC 377 S K DI+S G +VLE+ GK+ +L ++ + + K + + ++ + Sbjct: 1358 SAKVDIWSLGCIVLEMFAGKRPWS------NLEVVAAMFKIGKSKSAPPIPEDTLPLI-- 1409 Query: 376 DHSQVRRCIQVALLCVDMNPRNRPLMSSIV 287 SQ+ R A C ++NP RP + ++ Sbjct: 1410 --SQIGRNFLDA--CFEINPEKRPTANELL 1435
>NEK4_HUMAN (P51957) Serine/threonine-protein kinase Nek4 (EC 2.7.11.1)| (NimA-related protein kinase 4) (Serine/threonine-protein kinase 2) (Serine/threonine-protein kinase NRK2) Length = 841 Score = 60.8 bits (146), Expect = 4e-09 Identities = 35/79 (44%), Positives = 46/79 (58%) Frame = -2 Query: 733 IIHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTAYTLKVIGTYGYMSPEYAMDGVFS 554 I+HRD+K NV L R I K+ D GIAR+ A TL IGT YMSPE + ++ Sbjct: 127 ILHRDLKTQNVFLTRTNIIKVGDLGIARVLENHCDMASTL--IGTPYYMSPELFSNKPYN 184 Query: 553 MKSDIYSFGVMVLEIVTGK 497 KSD+++ G V E+ T K Sbjct: 185 YKSDVWALGCCVYEMATLK 203
>FRK_HUMAN (P42685) Tyrosine-protein kinase FRK (EC 2.7.10.2) (Nuclear| tyrosine protein kinase RAK) Length = 505 Score = 60.8 bits (146), Expect = 4e-09 Identities = 31/78 (39%), Positives = 49/78 (62%), Gaps = 2/78 (2%) Frame = -2 Query: 730 IHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTAYTLK--VIGTYGYMSPEYAMDGVF 557 IHRD+ A NVL+ + I K++DFG+AR+F D Y + + + +PE F Sbjct: 351 IHRDLAARNVLVGEHNIYKVADFGLARVFKVDNEDIYESRHEIKLPVKWTAPEAIRSNKF 410 Query: 556 SMKSDIYSFGVMVLEIVT 503 S+KSD++SFG+++ EI+T Sbjct: 411 SIKSDVWSFGILLYEIIT 428
>M3K10_HUMAN (Q02779) Mitogen-activated protein kinase kinase kinase 10 (EC| 2.7.11.25) (Mixed lineage kinase 2) (Protein kinase MST) Length = 954 Score = 60.8 bits (146), Expect = 4e-09 Identities = 35/87 (40%), Positives = 57/87 (65%), Gaps = 8/87 (9%) Frame = -2 Query: 733 IIHRDMKASNVLL-----DRNM---IPKISDFGIARMFGGDQTTAYTLKVIGTYGYMSPE 578 IIHRD+K+ N+L+ + N+ + KI+DFG+AR + +TT + GTY +M+PE Sbjct: 218 IIHRDLKSINILILEAIENHNLADTVLKITDFGLAREW--HKTTK--MSAAGTYAWMAPE 273 Query: 577 YAMDGVFSMKSDIYSFGVMVLEIVTGK 497 +FS SD++SFGV++ E++TG+ Sbjct: 274 VIRLSLFSKSSDVWSFGVLLWELLTGE 300
>MEK2_CAEEL (Q10664) Dual specificity mitogen-activated protein kinase kinase| mek-2 (EC 2.7.12.2) (MAP kinase kinase mek-2) Length = 387 Score = 60.5 bits (145), Expect = 5e-09 Identities = 28/81 (34%), Positives = 52/81 (64%) Frame = -2 Query: 739 LRIIHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTAYTLKVIGTYGYMSPEYAMDGV 560 ++I+HRD+K SN+L++ N K+ DFG++ M ++ +GT YM+PE Sbjct: 189 IKILHRDVKPSNMLVNSNGEIKLCDFGVSGMLIDSMANSF----VGTRSYMAPERLTGSH 244 Query: 559 FSMKSDIYSFGVMVLEIVTGK 497 +++ SDI+SFG+ ++E++ G+ Sbjct: 245 YTISSDIWSFGLSLVELLIGR 265
>LCK_CHICK (P42683) Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2)| (Protein-tyrosine kinase C-TKL) (p56tk1) Length = 507 Score = 60.5 bits (145), Expect = 5e-09 Identities = 31/81 (38%), Positives = 53/81 (65%), Gaps = 5/81 (6%) Frame = -2 Query: 730 IHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTA-----YTLKVIGTYGYMSPEYAMD 566 IHRD++A+N+L+ + KI+DFG+AR+ ++ TA + +K + +PE Sbjct: 359 IHRDLRAANILVSEALCCKIADFGLARLIEDNEYTAREGAKFPIK------WTAPEAINY 412 Query: 565 GVFSMKSDIYSFGVMVLEIVT 503 G F++KSD++SFG+++ EIVT Sbjct: 413 GTFTIKSDVWSFGILLTEIVT 433
>KIC1_YEAST (P38692) Serine/threonine-protein kinase KIC1 (EC 2.7.11.1) (Kinase| that interacts with CDC31) (N-rich kinase 1) Length = 1080 Score = 60.5 bits (145), Expect = 5e-09 Identities = 45/143 (31%), Positives = 70/143 (48%), Gaps = 1/143 (0%) Frame = -2 Query: 733 IIHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTAYTLKVIGTYGYMSPEYAMDGV-F 557 +IHRD+KA+NVL+ K+ DFG+A +QT+ + GT +M+PE M+GV + Sbjct: 140 VIHRDIKAANVLITNEGNVKLCDFGVAAQV--NQTSLRRQTMAGTPYWMAPEVIMEGVYY 197 Query: 556 SMKSDIYSFGVMVLEIVTGKKNRGFYDAELDLNLLGYAWTLWKEGRSTELLDEAMMGSSC 377 K DI+S G+ EI TG N + D E R+ +L+ ++ Sbjct: 198 DTKVDIWSLGITTYEIATG--NPPYCDVE--------------ALRAMQLIIKSKPPRLE 241 Query: 376 DHSQVRRCIQVALLCVDMNPRNR 308 D S + LC+D +P+ R Sbjct: 242 DRSYSTSLKEFIALCLDEDPKER 264
>RAF1_CHICK (P05625) RAF proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (RAF-1) (C-RAF) (MIL proto-oncogene serine/threonine-protein kinase) (C-MIL) Length = 647 Score = 60.5 bits (145), Expect = 5e-09 Identities = 50/199 (25%), Positives = 90/199 (45%), Gaps = 6/199 (3%) Frame = -2 Query: 733 IIHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTAYTLKVIGTYGYMSPEYAM---DG 563 IIHRDMK++N+ L + KI DFG+A + + + G+ +M+PE Sbjct: 464 IIHRDMKSNNIFLHEGLTVKIGDFGLATVKSRWSGSQQVEQPTGSILWMAPEVIRMQDSN 523 Query: 562 VFSMKSDIYSFGVMVLEIVTGKKNRGFYDAELDLNLLGYAWTLWKEGRSTELLDEAMMGS 383 FS +SD+YS+G+++ E++TG+ + + ++ GR D + + Sbjct: 524 PFSFQSDVYSYGIVLYELMTGELPYSHINNRDQI--------IFMVGRGYASPDLSKLYK 575 Query: 382 SCDHSQVRRCIQVALLCVDMNPRNRPLMSSIVMMLATENATLPEPNEPGGNVGKSTSDGE 203 +C + R + C+ RPL I+ + +LP+ + +S S+ Sbjct: 576 NCPKAMKR----LVADCLKKVREERPLFPQILSSIELLQHSLPK-------INRSASEPS 624 Query: 202 L---SQTQSELTVTVTDTR 155 L S T+ + T+T TR Sbjct: 625 LHRASHTEDINSCTLTSTR 643
>M3K11_HUMAN (Q16584) Mitogen-activated protein kinase kinase kinase 11 (EC| 2.7.11.25) (Mixed lineage kinase 3) (Src-homology 3 domain-containing proline-rich kinase) Length = 847 Score = 60.1 bits (144), Expect = 7e-09 Identities = 34/87 (39%), Positives = 55/87 (63%), Gaps = 8/87 (9%) Frame = -2 Query: 733 IIHRDMKASNVLLDR--------NMIPKISDFGIARMFGGDQTTAYTLKVIGTYGYMSPE 578 +IHRD+K++N+LL + + KI+DFG+AR + +TT + GTY +M+PE Sbjct: 237 VIHRDLKSNNILLLQPIESDDMEHKTLKITDFGLAREW--HKTTQ--MSAAGTYAWMAPE 292 Query: 577 YAMDGVFSMKSDIYSFGVMVLEIVTGK 497 FS SD++SFGV++ E++TG+ Sbjct: 293 VIKASTFSKGSDVWSFGVLLWELLTGE 319
>CHK1_YEAST (P38147) Serine/threonine-protein kinase CHK1 (EC 2.7.11.1)| (Checkpoint kinase 1) Length = 527 Score = 60.1 bits (144), Expect = 7e-09 Identities = 30/82 (36%), Positives = 54/82 (65%), Gaps = 3/82 (3%) Frame = -2 Query: 733 IIHRDMKASNVLLDRNMIPKISDFGIARMF-GGDQTTAYTLKVIGTYGYMSPE--YAMDG 563 + HRD+K N+LLD+N K++DFG+A F D T ++ G+ YM+PE Y+ +G Sbjct: 138 VAHRDIKPENILLDKNGNLKLADFGLASQFRRKDGTLRVSMDQRGSPPYMAPEVLYSEEG 197 Query: 562 VFSMKSDIYSFGVMVLEIVTGK 497 ++ ++DI+S G+++ ++TG+ Sbjct: 198 YYADRTDIWSIGILLFVLLTGQ 219
>SPK1_DUGTI (P42687) Tyrosine-protein kinase SPK-1 (EC 2.7.10.2)| Length = 497 Score = 60.1 bits (144), Expect = 7e-09 Identities = 25/78 (32%), Positives = 49/78 (62%) Frame = -2 Query: 736 RIIHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTAYTLKVIGTYGYMSPEYAMDGVF 557 +++HRD++A N+L+ ++ K++DFG+ + G + Y + +PE A VF Sbjct: 337 KVVHRDLRADNILVANDLTRKVADFGLTELTDGSLGDQEKKTLRFPYKWTAPEAAKSKVF 396 Query: 556 SMKSDIYSFGVMVLEIVT 503 + KSD++S+G+++ EI+T Sbjct: 397 TSKSDVWSYGIVMFEILT 414
>PKH1_YEAST (Q03407) Serine/threonine-protein kinase PKH1 (EC 2.7.11.1)| (3-phosphoinositide-dependent protein kinase 1) Length = 766 Score = 60.1 bits (144), Expect = 7e-09 Identities = 31/90 (34%), Positives = 51/90 (56%), Gaps = 11/90 (12%) Frame = -2 Query: 733 IIHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTT-----------AYTLKVIGTYGYM 587 IIHRD+K N+LLD+NM K++DFG A++ + + A + +GT Y+ Sbjct: 245 IIHRDIKPENILLDKNMKVKLTDFGTAKILPEEPSNTADGKPYFDLYAKSKSFVGTAEYV 304 Query: 586 SPEYAMDGVFSMKSDIYSFGVMVLEIVTGK 497 SPE D + DI++FG ++ +++ GK Sbjct: 305 SPELLNDNYTDSRCDIWAFGCILYQMLAGK 334
>EPHA8_HUMAN (P29322) Ephrin type-A receptor 8 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EEK) (EPH- and ELK-related kinase) (HEK3) Length = 1005 Score = 60.1 bits (144), Expect = 7e-09 Identities = 32/81 (39%), Positives = 50/81 (61%), Gaps = 3/81 (3%) Frame = -2 Query: 739 LRIIHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTAYTL---KVIGTYGYMSPEYAM 569 L +HRD+ A NVL+D N++ K+SDFG++R+ D AYT K+ + +PE Sbjct: 754 LGYVHRDLAARNVLVDSNLVCKVSDFGLSRVLEDDPDAAYTTTGGKI--PIRWTAPEAIA 811 Query: 568 DGVFSMKSDIYSFGVMVLEIV 506 FS SD++SFGV++ E++ Sbjct: 812 FRTFSSASDVWSFGVVMWEVL 832
>LCK_SAISC (Q95KR7) Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2)| (p56-LCK) (Lymphocyte cell-specific protein-tyrosine kinase) Length = 508 Score = 60.1 bits (144), Expect = 7e-09 Identities = 31/81 (38%), Positives = 53/81 (65%), Gaps = 5/81 (6%) Frame = -2 Query: 730 IHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTA-----YTLKVIGTYGYMSPEYAMD 566 IHRD++A+N+L+ + KI+DFG+AR+ ++ TA + +K + +PE Sbjct: 360 IHRDLRAANILVSDTLSCKIADFGLARLIEDNEYTAREGAKFPIK------WTAPEAINY 413 Query: 565 GVFSMKSDIYSFGVMVLEIVT 503 G F++KSD++SFG+++ EIVT Sbjct: 414 GTFTIKSDVWSFGILMTEIVT 434
>LCK_MOUSE (P06240) Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2)| (p56-LCK) (Lymphocyte cell-specific protein-tyrosine kinase) (LSK) Length = 508 Score = 60.1 bits (144), Expect = 7e-09 Identities = 31/81 (38%), Positives = 53/81 (65%), Gaps = 5/81 (6%) Frame = -2 Query: 730 IHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTA-----YTLKVIGTYGYMSPEYAMD 566 IHRD++A+N+L+ + KI+DFG+AR+ ++ TA + +K + +PE Sbjct: 360 IHRDLRAANILVSDTLSCKIADFGLARLIEDNEYTAREGAKFPIK------WTAPEAINY 413 Query: 565 GVFSMKSDIYSFGVMVLEIVT 503 G F++KSD++SFG+++ EIVT Sbjct: 414 GTFTIKSDVWSFGILLTEIVT 434
>LCK_HUMAN (P06239) Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2)| (p56-LCK) (Lymphocyte cell-specific protein-tyrosine kinase) (LSK) (T cell-specific protein-tyrosine kinase) Length = 508 Score = 60.1 bits (144), Expect = 7e-09 Identities = 31/81 (38%), Positives = 53/81 (65%), Gaps = 5/81 (6%) Frame = -2 Query: 730 IHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTA-----YTLKVIGTYGYMSPEYAMD 566 IHRD++A+N+L+ + KI+DFG+AR+ ++ TA + +K + +PE Sbjct: 360 IHRDLRAANILVSDTLSCKIADFGLARLIEDNEYTAREGAKFPIK------WTAPEAINY 413 Query: 565 GVFSMKSDIYSFGVMVLEIVT 503 G F++KSD++SFG+++ EIVT Sbjct: 414 GTFTIKSDVWSFGILLTEIVT 434
>LCK_AOTNA (Q5PXS1) Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2)| (p56-LCK) (Lymphocyte cell-specific protein-tyrosine kinase) Length = 508 Score = 60.1 bits (144), Expect = 7e-09 Identities = 31/81 (38%), Positives = 53/81 (65%), Gaps = 5/81 (6%) Frame = -2 Query: 730 IHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTA-----YTLKVIGTYGYMSPEYAMD 566 IHRD++A+N+L+ + KI+DFG+AR+ ++ TA + +K + +PE Sbjct: 360 IHRDLRAANILVSDTLSCKIADFGLARLIEDNEYTAREGAKFPIK------WTAPEAINY 413 Query: 565 GVFSMKSDIYSFGVMVLEIVT 503 G F++KSD++SFG+++ EIVT Sbjct: 414 GTFTIKSDVWSFGILLTEIVT 434
>KRAF1_DROME (P11346) Raf homolog serine/threonine-protein kinase dRAF-1 (EC| 2.7.11.1) (Protein pole-hole) Length = 739 Score = 60.1 bits (144), Expect = 7e-09 Identities = 52/189 (27%), Positives = 89/189 (47%), Gaps = 7/189 (3%) Frame = -2 Query: 733 IIHRDMKASNVLLDRNMIPKISDFGIA----RMFGGDQTTAYTLKVIGTYGYMSPEYAMD 566 IIHRD+K++N+ L ++ KI DFG+A R G Q T G+ +M+PE Sbjct: 544 IIHRDLKSNNIFLHEDLSVKIGDFGLATAKTRWSGEKQANQPT----GSILWMAPEVIRM 599 Query: 565 ---GVFSMKSDIYSFGVMVLEIVTGKKNRGFYDAELDLNLLGYAWTLWKEGRSTELLDEA 395 +S +SD+Y+FG+++ E++ G + + L+ GR D + Sbjct: 600 QELNPYSFQSDVYAFGIVMYELLAECLPYGHISNKDQI--------LFMVGRGLLRPDMS 651 Query: 394 MMGSSCDHSQVRRCIQVALLCVDMNPRNRPLMSSIVMMLATENATLPEPNEPGGNVGKST 215 + S + R +A C+ P++RPL ++ ML TLP+ + +S Sbjct: 652 QVRSDAPQALKR----LAEDCIKYTPKDRPLFRPLLNMLENMLRTLPK-------IHRSA 700 Query: 214 SDGELSQTQ 188 S+ L+Q+Q Sbjct: 701 SEPNLTQSQ 709
>FGR_FSVGR (P00544) Tyrosine-protein kinase transforming protein Fgr (EC| 2.7.10.2) Length = 545 Score = 59.7 bits (143), Expect = 9e-09 Identities = 28/81 (34%), Positives = 54/81 (66%), Gaps = 5/81 (6%) Frame = -2 Query: 730 IHRDMKASNVLLDRNMIPKISDFGIARM-----FGGDQTTAYTLKVIGTYGYMSPEYAMD 566 IHRD++A+N+L+ ++ KI+DFG+AR+ + Q + +K + +PE A+ Sbjct: 402 IHRDLRAANILVGERLVCKIADFGLARLIEDNEYNPRQGAKFPIK------WTAPEAALF 455 Query: 565 GVFSMKSDIYSFGVMVLEIVT 503 G F++KSD++SFG+++ E+++ Sbjct: 456 GRFTIKSDVWSFGILLTELIS 476
>CDC5_YEAST (P32562) Cell cycle serine/threonine-protein kinase CDC5/MSD2 (EC| 2.7.11.21) Length = 705 Score = 59.7 bits (143), Expect = 9e-09 Identities = 32/82 (39%), Positives = 46/82 (56%), Gaps = 2/82 (2%) Frame = -2 Query: 736 RIIHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTAYTLKVIGTYGYMSPEYAM--DG 563 R+IHRD+K N+ D N KI DFG+A + + YT + GT Y++PE M Sbjct: 199 RVIHRDLKLGNIFFDSNYNLKIGDFGLAAVLANESERKYT--ICGTPNYIAPEVLMGKHS 256 Query: 562 VFSMKSDIYSFGVMVLEIVTGK 497 S + DI+S GVM+ ++ GK Sbjct: 257 GHSFEVDIWSLGVMLYALLIGK 278
>NEK2_HUMAN (P51955) Serine/threonine-protein kinase Nek2 (EC 2.7.11.1)| (NimA-related protein kinase 2) (NimA-like protein kinase 1) (HSPK 21) Length = 445 Score = 59.7 bits (143), Expect = 9e-09 Identities = 30/75 (40%), Positives = 46/75 (61%) Frame = -2 Query: 733 IIHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTAYTLKVIGTYGYMSPEYAMDGVFS 554 ++HRD+K +NV LD K+ DFG+AR+ D T++ +GT YMSPE ++ Sbjct: 137 VLHRDLKPANVFLDGKQNVKLGDFGLARILNHD--TSFAKTFVGTPYYMSPEQMNRMSYN 194 Query: 553 MKSDIYSFGVMVLEI 509 KSDI+S G ++ E+ Sbjct: 195 EKSDIWSLGCLLYEL 209
>IKKB_DROME (Q9VEZ5) Inhibitor of nuclear factor kappa B kinase beta subunit| (EC 2.7.11.1) (DmIKK-beta) (Immune response deficient protein 5) (IKK-like protein) (Lipopolysaccharide-activated kinase) (DLAK) (Cactus kinase IKK) Length = 751 Score = 59.7 bits (143), Expect = 9e-09 Identities = 31/83 (37%), Positives = 49/83 (59%), Gaps = 4/83 (4%) Frame = -2 Query: 733 IIHRDMKASNVLLDRNM----IPKISDFGIARMFGGDQTTAYTLKVIGTYGYMSPEYAMD 566 I HRD+K N+++ R + I K++DFG+AR G V+GT Y +PE + Sbjct: 180 ICHRDLKPDNIVIQRGVDGKKIYKLTDFGLAR---GTPDQTMVQSVVGTRHYYAPEVVEN 236 Query: 565 GVFSMKSDIYSFGVMVLEIVTGK 497 G ++ D++SFGV+ E+VTG+ Sbjct: 237 GFYNSTVDLWSFGVIAYELVTGE 259
>HCK_MACFA (Q95M30) Tyrosine-protein kinase HCK (EC 2.7.10.2) (p56-HCK)| (Hemopoietic cell kinase) Length = 503 Score = 59.7 bits (143), Expect = 9e-09 Identities = 30/81 (37%), Positives = 55/81 (67%), Gaps = 5/81 (6%) Frame = -2 Query: 730 IHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTA-----YTLKVIGTYGYMSPEYAMD 566 IHRD++A+N+L+ +++ KI+DFG+AR+ ++ TA + +K + +PE Sbjct: 355 IHRDLRAANILVSASLVCKIADFGLARIIEDNEYTAREGAKFPIK------WTAPEAINF 408 Query: 565 GVFSMKSDIYSFGVMVLEIVT 503 G ++KSD++SFG++++EIVT Sbjct: 409 GSSTIKSDVWSFGILLMEIVT 429
>ABL2_HUMAN (P42684) Tyrosine-protein kinase ABL2 (EC 2.7.10.2) (Abelson murine| leukemia viral oncogene homolog 2) (Tyrosine kinase ARG) Length = 1182 Score = 59.7 bits (143), Expect = 9e-09 Identities = 30/76 (39%), Positives = 47/76 (61%) Frame = -2 Query: 730 IHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTAYTLKVIGTYGYMSPEYAMDGVFSM 551 IHRD+ A N L+ N + K++DFG++R+ GD TA+ + +PE FS+ Sbjct: 406 IHRDLAARNCLVGENHVVKVADFGLSRLMTGDTYTAHAGAKF-PIKWTAPESLAYNTFSI 464 Query: 550 KSDIYSFGVMVLEIVT 503 KSD+++FGV++ EI T Sbjct: 465 KSDVWAFGVLLWEIAT 480
>M3K13_HUMAN (O43283) Mitogen-activated protein kinase kinase kinase 13 (EC| 2.7.11.25) (Mixed lineage kinase) (MLK) (Leucine zipper-bearing kinase) Length = 966 Score = 59.7 bits (143), Expect = 9e-09 Identities = 32/80 (40%), Positives = 48/80 (60%) Frame = -2 Query: 736 RIIHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTAYTLKVIGTYGYMSPEYAMDGVF 557 +IIHRD+K+ NVL+ KISDFG ++ T + GT +M+PE + Sbjct: 274 KIIHRDLKSPNVLVTHTDAVKISDFGTSKELSDKSTK---MSFAGTVAWMAPEVIRNEPV 330 Query: 556 SMKSDIYSFGVMVLEIVTGK 497 S K DI+SFGV++ E++TG+ Sbjct: 331 SEKVDIWSFGVVLWELLTGE 350
>PDPK1_RAT (O55173) 3-phosphoinositide-dependent protein kinase 1 (EC| 2.7.11.1) (Protein kinase B kinase) (PkB kinase) Length = 559 Score = 59.7 bits (143), Expect = 9e-09 Identities = 28/78 (35%), Positives = 46/78 (58%) Frame = -2 Query: 733 IIHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTAYTLKVIGTYGYMSPEYAMDGVFS 554 IIHRD+K N+LL+ +M +I+DFG A++ D A +GT Y+SPE + Sbjct: 204 IIHRDLKPENILLNEDMHIQITDFGTAKVLSPDSKQARANSFVGTAQYVSPELLTEKSAC 263 Query: 553 MKSDIYSFGVMVLEIVTG 500 SD+++ G ++ ++V G Sbjct: 264 KSSDLWALGCIIYQLVAG 281
>CDC21_XENLA (P35567) Cell division control protein 2 homolog 1 (EC 2.7.11.22)| (EC 2.7.11.23) (p34 protein kinase 1) Length = 302 Score = 59.3 bits (142), Expect = 1e-08 Identities = 36/92 (39%), Positives = 55/92 (59%), Gaps = 1/92 (1%) Frame = -2 Query: 736 RIIHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTAYTLKVIGTYGYMSPEYAMDGV- 560 R++HRD+K N+L+D + K++DFG+AR F G YT +V+ T Y +PE + V Sbjct: 123 RVLHRDLKPQNLLIDSKGVIKLADFGLARAF-GIPVRVYTHEVV-TLWYRAPEVLLGSVR 180 Query: 559 FSMKSDIYSFGVMVLEIVTGKKNRGFYDAELD 464 +S D++S G + EI T KK D+E+D Sbjct: 181 YSTPVDVWSIGTIFAEIAT-KKPLFHGDSEID 211
>RAF1_RAT (P11345) RAF proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (Raf-1) (C-RAF) (cRaf) Length = 648 Score = 59.3 bits (142), Expect = 1e-08 Identities = 43/166 (25%), Positives = 77/166 (46%), Gaps = 3/166 (1%) Frame = -2 Query: 733 IIHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTAYTLKVIGTYGYMSPEYAM---DG 563 IIHRDMK++N+ L + KI DFG+A + + + G+ +M+PE + Sbjct: 464 IIHRDMKSNNIFLHEGLTVKIGDFGLATVKSRWSGSQQVEQPTGSVLWMAPEVIRMQDNN 523 Query: 562 VFSMKSDIYSFGVMVLEIVTGKKNRGFYDAELDLNLLGYAWTLWKEGRSTELLDEAMMGS 383 FS +SD+YS+G+++ E++TG+ + + ++ GR D + + Sbjct: 524 PFSFQSDVYSYGIVLYELMTGELPYSHINNRDQI--------IFMVGRGYASPDLSRLYK 575 Query: 382 SCDHSQVRRCIQVALLCVDMNPRNRPLMSSIVMMLATENATLPEPN 245 +C + R + CV RPL I+ + +LP+ N Sbjct: 576 NCPKAMKR----LVADCVKKVKEERPLFPQILSSIELLQHSLPKIN 617
>RAF1_MOUSE (Q99N57) RAF proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (Raf-1) (C-RAF) (cRaf) Length = 648 Score = 59.3 bits (142), Expect = 1e-08 Identities = 43/166 (25%), Positives = 76/166 (45%), Gaps = 3/166 (1%) Frame = -2 Query: 733 IIHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTAYTLKVIGTYGYMSPEYAM---DG 563 IIHRDMK++N+ L + KI DFG+A + + + G+ +M+PE D Sbjct: 464 IIHRDMKSNNIFLHEGLTVKIGDFGLATVKSRWSGSQQVEQPTGSVLWMAPEVIRMQDDN 523 Query: 562 VFSMKSDIYSFGVMVLEIVTGKKNRGFYDAELDLNLLGYAWTLWKEGRSTELLDEAMMGS 383 FS +SD+YS+G+++ E++ G+ + + ++ GR D + + Sbjct: 524 PFSFQSDVYSYGIVLYELMAGELPYAHINNRDQI--------IFMVGRGYASPDLSRLYK 575 Query: 382 SCDHSQVRRCIQVALLCVDMNPRNRPLMSSIVMMLATENATLPEPN 245 +C + R + CV RPL I+ + +LP+ N Sbjct: 576 NCPKAMKR----LVADCVKKVKEERPLFPQILSSIELLQHSLPKIN 617
>RAF1_HUMAN (P04049) RAF proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (Raf-1) (C-RAF) (cRaf) Length = 648 Score = 59.3 bits (142), Expect = 1e-08 Identities = 43/166 (25%), Positives = 77/166 (46%), Gaps = 3/166 (1%) Frame = -2 Query: 733 IIHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTAYTLKVIGTYGYMSPEYAM---DG 563 IIHRDMK++N+ L + KI DFG+A + + + G+ +M+PE + Sbjct: 464 IIHRDMKSNNIFLHEGLTVKIGDFGLATVKSRWSGSQQVEQPTGSVLWMAPEVIRMQDNN 523 Query: 562 VFSMKSDIYSFGVMVLEIVTGKKNRGFYDAELDLNLLGYAWTLWKEGRSTELLDEAMMGS 383 FS +SD+YS+G+++ E++TG+ + + ++ GR D + + Sbjct: 524 PFSFQSDVYSYGIVLYELMTGELPYSHINNRDQI--------IFMVGRGYASPDLSKLYK 575 Query: 382 SCDHSQVRRCIQVALLCVDMNPRNRPLMSSIVMMLATENATLPEPN 245 +C + R + CV RPL I+ + +LP+ N Sbjct: 576 NCPKAMKR----LVADCVKKVKEERPLFPQILSSIELLQHSLPKIN 617
>PKN2_MYXXA (P54736) Serine/threonine-protein kinase pkn2 (EC 2.7.11.1)| Length = 830 Score = 59.3 bits (142), Expect = 1e-08 Identities = 36/99 (36%), Positives = 55/99 (55%), Gaps = 5/99 (5%) Frame = -2 Query: 733 IIHRDMKASNVLLD---RNMIPKISDFGIARMFGGDQTTAYTL--KVIGTYGYMSPEYAM 569 IIHRD+K NV + R ++ DFGIAR+ D ++ + V+GT Y+SPE A+ Sbjct: 131 IIHRDLKPENVFISKSARGEQARLLDFGIARLVEPDAASSVSQIGVVLGTPEYLSPEQAV 190 Query: 568 DGVFSMKSDIYSFGVMVLEIVTGKKNRGFYDAELDLNLL 452 +SD+YSFGV+ +++G+ +D L N L Sbjct: 191 GAKVDTRSDLYSFGVLTYRVLSGRLP---FDGPLPRNFL 226
>PKNA_MYCLE (P54743) Probable serine/threonine-protein kinase pknA (EC| 2.7.11.1) Length = 437 Score = 59.3 bits (142), Expect = 1e-08 Identities = 32/80 (40%), Positives = 49/80 (61%) Frame = -2 Query: 733 IIHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTAYTLKVIGTYGYMSPEYAMDGVFS 554 ++HRD+K N+L+ KI+DFGIA+ T T V+GT Y++PE A+ + Sbjct: 137 LVHRDVKPGNILITPTGQVKITDFGIAKAVDAAPVTQ-TGMVMGTAQYIAPEQALGHDAT 195 Query: 553 MKSDIYSFGVMVLEIVTGKK 494 SD+YS GV+ E+V+GK+ Sbjct: 196 PASDVYSLGVIGYEVVSGKR 215
>ABL_FSVHY (P10447) Tyrosine-protein kinase transforming protein Abl (EC| 2.7.10.2) (V-abl) Length = 439 Score = 59.3 bits (142), Expect = 1e-08 Identities = 32/79 (40%), Positives = 49/79 (62%), Gaps = 3/79 (3%) Frame = -2 Query: 730 IHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTAYTLKVIGT---YGYMSPEYAMDGV 560 IHRD+ A N L+ N + K++DFG++R+ GD TA+ GT + +PE Sbjct: 309 IHRDLAARNCLVGENHLVKVADFGLSRLMTGDTYTAHA----GTKFPIKWTAPESLAYNK 364 Query: 559 FSMKSDIYSFGVMVLEIVT 503 FS+KSD+++FGV++ EI T Sbjct: 365 FSIKSDVWAFGVLLWEIAT 383
>M3KSL_DROME (Q95UN8) Mitogen-activated protein kinase kinase kinase (EC| 2.7.11.25) (Mixed lineage kinase) (dMLK) (Protein slipper) Length = 1161 Score = 59.3 bits (142), Expect = 1e-08 Identities = 34/89 (38%), Positives = 53/89 (59%), Gaps = 8/89 (8%) Frame = -2 Query: 739 LRIIHRDMKASNVLL----DRNMIP----KISDFGIARMFGGDQTTAYTLKVIGTYGYMS 584 + IIHRD+K+SNVL+ + N + KI+DFG+AR Q + GTY +M Sbjct: 258 MSIIHRDLKSSNVLIYEAIEGNHLQQKTLKITDFGLAREMYNTQR----MSAAGTYAWMP 313 Query: 583 PEYAMDGVFSMKSDIYSFGVMVLEIVTGK 497 PE +S SD++S+GV++ E++TG+ Sbjct: 314 PEVISVSTYSKFSDVWSYGVLLWELITGE 342
>SRC42_DROME (Q9V9J3) Tyrosine-protein kinase Src42A (EC 2.7.10.2) (Dsrc41)| Length = 517 Score = 58.9 bits (141), Expect = 2e-08 Identities = 33/78 (42%), Positives = 50/78 (64%), Gaps = 2/78 (2%) Frame = -2 Query: 730 IHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTAYTLKVIGTY--GYMSPEYAMDGVF 557 IHRD+ A NVL+ I KI+DFG+AR+ D+ Y +V + + +PE A F Sbjct: 367 IHRDLAARNVLVGDGNIVKIADFGLARLIKEDE---YEARVGARFPIKWTAPEAANYSKF 423 Query: 556 SMKSDIYSFGVMVLEIVT 503 S+KSD++SFG+++ E+VT Sbjct: 424 SIKSDVWSFGILLTELVT 441
>KOIA_SCHPO (Q9Y7J6) Putative serine/threonine-protein kinase C1778.10c (EC| 2.7.11.1) Length = 550 Score = 58.9 bits (141), Expect = 2e-08 Identities = 30/83 (36%), Positives = 46/83 (55%), Gaps = 5/83 (6%) Frame = -2 Query: 733 IIHRDMKASNVLLDRNMIPKISDFGIARMF-----GGDQTTAYTLKVIGTYGYMSPEYAM 569 IIHRD+K N+L D NM KI+DFG A++ T + +GT Y++PE Sbjct: 174 IIHRDLKPENILFDGNMHVKITDFGTAKILPPKYVNSPDYTTFPSSFVGTAEYVAPELLS 233 Query: 568 DGVFSMKSDIYSFGVMVLEIVTG 500 V S SD+++F +V +++ G Sbjct: 234 RQVVSKSSDLWAFACVVYQMIVG 256
>PKNA_MYCTU (P65726) Probable serine/threonine-protein kinase pknA (EC| 2.7.11.1) Length = 431 Score = 58.9 bits (141), Expect = 2e-08 Identities = 33/80 (41%), Positives = 48/80 (60%) Frame = -2 Query: 733 IIHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTAYTLKVIGTYGYMSPEYAMDGVFS 554 ++HRD+K N+L+ KI+DFGIA+ T T V+GT Y++PE A+ S Sbjct: 137 LVHRDVKPGNILITPTGQVKITDFGIAKAVDAAPVTQ-TGMVMGTAQYIAPEQALGHDAS 195 Query: 553 MKSDIYSFGVMVLEIVTGKK 494 SD+YS GV+ E V+GK+ Sbjct: 196 PASDVYSLGVVGYEAVSGKR 215
>PKNA_MYCBO (P65727) Probable serine/threonine-protein kinase pknA (EC| 2.7.11.1) Length = 431 Score = 58.9 bits (141), Expect = 2e-08 Identities = 33/80 (41%), Positives = 48/80 (60%) Frame = -2 Query: 733 IIHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTAYTLKVIGTYGYMSPEYAMDGVFS 554 ++HRD+K N+L+ KI+DFGIA+ T T V+GT Y++PE A+ S Sbjct: 137 LVHRDVKPGNILITPTGQVKITDFGIAKAVDAAPVTQ-TGMVMGTAQYIAPEQALGHDAS 195 Query: 553 MKSDIYSFGVMVLEIVTGKK 494 SD+YS GV+ E V+GK+ Sbjct: 196 PASDVYSLGVVGYEAVSGKR 215
>SRMS_MOUSE (Q62270) Tyrosine-protein kinase Srms (EC 2.7.10.2) (PTK70)| Length = 496 Score = 58.9 bits (141), Expect = 2e-08 Identities = 30/78 (38%), Positives = 50/78 (64%) Frame = -2 Query: 736 RIIHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTAYTLKVIGTYGYMSPEYAMDGVF 557 R++HRD+ A NVL+ ++ K++DFG+AR+ D + + I + +PE A VF Sbjct: 349 RVVHRDLAARNVLVGDDLTCKVADFGLARLLKDDVYSPSSGSKI-PVKWTAPEAANYRVF 407 Query: 556 SMKSDIYSFGVMVLEIVT 503 S KSD++SFG+++ E+ T Sbjct: 408 SQKSDVWSFGILLYEVFT 425
>CDC2_CHICK (P13863) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1) Length = 303 Score = 58.9 bits (141), Expect = 2e-08 Identities = 36/92 (39%), Positives = 55/92 (59%), Gaps = 1/92 (1%) Frame = -2 Query: 736 RIIHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTAYTLKVIGTYGYMSPEYAM-DGV 560 R++HRD+K N+L+D + K++DFG+AR F G YT +V+ T Y SPE + + Sbjct: 123 RVLHRDLKPQNLLIDDKGVIKLADFGLARAF-GIPVRVYTHEVV-TLWYRSPEVLLGSAL 180 Query: 559 FSMKSDIYSFGVMVLEIVTGKKNRGFYDAELD 464 +S DI+S G + E+ T KK D+E+D Sbjct: 181 YSTPVDIWSIGTIFAELAT-KKPLFHGDSEID 211
>ABL1_MOUSE (P00520) Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2)| (p150) (c-ABL) (Abelson murine leukemia viral oncogene homolog 1) Length = 1123 Score = 58.5 bits (140), Expect = 2e-08 Identities = 30/76 (39%), Positives = 47/76 (61%) Frame = -2 Query: 730 IHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTAYTLKVIGTYGYMSPEYAMDGVFSM 551 IHRD+ A N L+ N + K++DFG++R+ GD TA+ + +PE FS+ Sbjct: 360 IHRDLAARNCLVGENHLVKVADFGLSRLMTGDTYTAHAGAKF-PIKWTAPESLAYNKFSI 418 Query: 550 KSDIYSFGVMVLEIVT 503 KSD+++FGV++ EI T Sbjct: 419 KSDVWAFGVLLWEIAT 434
>RAF_MSV36 (P00532) Serine/threonine-protein kinase transforming protein raf| (EC 2.7.11.1) Length = 323 Score = 58.5 bits (140), Expect = 2e-08 Identities = 43/166 (25%), Positives = 78/166 (46%), Gaps = 3/166 (1%) Frame = -2 Query: 733 IIHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTAYTLKVIGTYGYMSPEYAM---DG 563 IIHRDMK++N+ L + KI DFG+A + + + G+ +M+PE D Sbjct: 139 IIHRDMKSNNIFLHEGLTVKIGDFGLATVKSRWSGSQQVEQPTGSVLWMAPEVIRMQDDN 198 Query: 562 VFSMKSDIYSFGVMVLEIVTGKKNRGFYDAELDLNLLGYAWTLWKEGRSTELLDEAMMGS 383 FS +SD+YS+G+++ E++ G+ + + ++ GR D + + Sbjct: 199 PFSFQSDVYSYGIVLYELMAGELPYAHINNRDQI--------IFMVGRGYASPDLSRLYK 250 Query: 382 SCDHSQVRRCIQVALLCVDMNPRNRPLMSSIVMMLATENATLPEPN 245 +C + ++R + CV RPL I+ + +LP+ N Sbjct: 251 NCPKA-IKRLVAD---CVKKVKEERPLFPQILSSIELLQHSLPKIN 292
>PTK6_MOUSE (Q64434) Tyrosine-protein kinase 6 (EC 2.7.10.2) (SRC-related| intestinal kinase) Length = 451 Score = 58.5 bits (140), Expect = 2e-08 Identities = 31/74 (41%), Positives = 47/74 (63%) Frame = -2 Query: 730 IHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTAYTLKVIGTYGYMSPEYAMDGVFSM 551 IHRD+ A NVL+ N + K+ DFG+AR+ D ++ V Y + +PE G +S+ Sbjct: 309 IHRDLAARNVLVTENNLCKVGDFGLARLVKEDIYLSHEHNV--PYKWTAPEALSRGHYSI 366 Query: 550 KSDIYSFGVMVLEI 509 KSD++SFGV++ EI Sbjct: 367 KSDVWSFGVLLHEI 380
>RAF1_XENLA (P09560) RAF proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (C-RAF) Length = 638 Score = 58.5 bits (140), Expect = 2e-08 Identities = 33/86 (38%), Positives = 51/86 (59%), Gaps = 7/86 (8%) Frame = -2 Query: 733 IIHRDMKASNVLLDRNMIPKISDFGIA----RMFGGDQTTAYTLKVIGTYGYMSPEYAM- 569 IIHRDMK++N+ L + KI DFG+A R G Q T G+ +M+PE Sbjct: 455 IIHRDMKSNNIFLHEGLTVKIGDFGLATVKTRWSGSQQVEQLT----GSILWMAPEVIRM 510 Query: 568 --DGVFSMKSDIYSFGVMVLEIVTGK 497 + FS +SD+YS+G+++ E++TG+ Sbjct: 511 QDNNPFSFQSDVYSYGIVLYELMTGE 536
>ABL_MLVAB (P00521) Tyrosine-protein kinase transforming protein Abl (EC| 2.7.10.2) (V-abl) Length = 746 Score = 58.5 bits (140), Expect = 2e-08 Identities = 30/76 (39%), Positives = 47/76 (61%) Frame = -2 Query: 730 IHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTAYTLKVIGTYGYMSPEYAMDGVFSM 551 IHRD+ A N L+ N + K++DFG++R+ GD TA+ + +PE FS+ Sbjct: 246 IHRDLAARNCLVGENHLVKVADFGLSRLMTGDTYTAHAGAKF-PIKWTAPESLAYNKFSI 304 Query: 550 KSDIYSFGVMVLEIVT 503 KSD+++FGV++ EI T Sbjct: 305 KSDVWAFGVLLWEIAT 320
>FGFR2_MOUSE (P21803) Fibroblast growth factor receptor 2 precursor (EC| 2.7.10.1) (FGFR-2) (Keratinocyte growth factor receptor) Length = 821 Score = 58.5 bits (140), Expect = 2e-08 Identities = 31/78 (39%), Positives = 46/78 (58%) Frame = -2 Query: 736 RIIHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTAYTLKVIGTYGYMSPEYAMDGVF 557 + IHRD+ A NVL+ N + KI+DFG+AR T +M+PE D V+ Sbjct: 621 KCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVY 680 Query: 556 SMKSDIYSFGVMVLEIVT 503 + +SD++SFGV++ EI T Sbjct: 681 THQSDVWSFGVLMWEIFT 698
>FGFR2_HUMAN (P21802) Fibroblast growth factor receptor 2 precursor (EC| 2.7.10.1) (FGFR-2) (Keratinocyte growth factor receptor 2) (CD332 antigen) Length = 821 Score = 58.5 bits (140), Expect = 2e-08 Identities = 31/78 (39%), Positives = 46/78 (58%) Frame = -2 Query: 736 RIIHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTAYTLKVIGTYGYMSPEYAMDGVF 557 + IHRD+ A NVL+ N + KI+DFG+AR T +M+PE D V+ Sbjct: 621 KCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVY 680 Query: 556 SMKSDIYSFGVMVLEIVT 503 + +SD++SFGV++ EI T Sbjct: 681 THQSDVWSFGVLMWEIFT 698
>SRK1_SPOLA (P42686) Tyrosine-protein kinase isoform SRK1 (EC 2.7.10.2)| Length = 505 Score = 58.5 bits (140), Expect = 2e-08 Identities = 31/76 (40%), Positives = 50/76 (65%) Frame = -2 Query: 730 IHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTAYTLKVIGTYGYMSPEYAMDGVFSM 551 IHRD+ A N+L+ + I K++DFG+AR+ + A+T + +PE AM F++ Sbjct: 356 IHRDLAARNILVGEHGICKVADFGLARVIDEEIYEAHTGAKF-PIKWTAPEAAMYNRFTI 414 Query: 550 KSDIYSFGVMVLEIVT 503 KSD++SFGV++ EI+T Sbjct: 415 KSDVWSFGVVLYEIIT 430
>SRK3_SPOLA (P42689) Tyrosine-protein kinase SRK3 (EC 2.7.10.2) (Fragment)| Length = 334 Score = 58.5 bits (140), Expect = 2e-08 Identities = 31/81 (38%), Positives = 51/81 (62%), Gaps = 5/81 (6%) Frame = -2 Query: 730 IHRDMKASNVLLDRNMIPKISDFGIARMFGGD-----QTTAYTLKVIGTYGYMSPEYAMD 566 IHRD+ A N+L+ + K++DFG+AR+ D + T + +K + +PE A+ Sbjct: 183 IHRDLAARNILVGEGNVCKVADFGLARVIKEDIYNPREGTKFPIK------WTAPEAALY 236 Query: 565 GVFSMKSDIYSFGVMVLEIVT 503 F++KSD++SFGV++ EIVT Sbjct: 237 NRFTIKSDVWSFGVLISEIVT 257
>CEK3_CHICK (P18461) Tyrosine kinase receptor CEK3 precursor (EC 2.7.10.1)| Length = 823 Score = 58.5 bits (140), Expect = 2e-08 Identities = 31/78 (39%), Positives = 46/78 (58%) Frame = -2 Query: 736 RIIHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTAYTLKVIGTYGYMSPEYAMDGVF 557 + IHRD+ A NVL+ N + KI+DFG+AR T +M+PE D V+ Sbjct: 623 KCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVY 682 Query: 556 SMKSDIYSFGVMVLEIVT 503 + +SD++SFGV++ EI T Sbjct: 683 THQSDVWSFGVLMWEIFT 700
>ABL1_HUMAN (P00519) Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2)| (p150) (c-ABL) (Abelson murine leukemia viral oncogene homolog 1) Length = 1130 Score = 58.5 bits (140), Expect = 2e-08 Identities = 30/76 (39%), Positives = 47/76 (61%) Frame = -2 Query: 730 IHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTAYTLKVIGTYGYMSPEYAMDGVFSM 551 IHRD+ A N L+ N + K++DFG++R+ GD TA+ + +PE FS+ Sbjct: 360 IHRDLAARNCLVGENHLVKVADFGLSRLMTGDTYTAHAGAKF-PIKWTAPESLAYNKFSI 418 Query: 550 KSDIYSFGVMVLEIVT 503 KSD+++FGV++ EI T Sbjct: 419 KSDVWAFGVLLWEIAT 434
>STE7_CANAL (P46599) Serine/threonine-protein kinase STE7 homolog (EC 2.7.12.2)| Length = 589 Score = 58.5 bits (140), Expect = 2e-08 Identities = 31/79 (39%), Positives = 48/79 (60%) Frame = -2 Query: 736 RIIHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTAYTLKVIGTYGYMSPEYAMDGVF 557 +IIHRD+K +NVL+ K+ DFG++R A T +GT YMSPE + Sbjct: 369 KIIHRDIKPNNVLMTHKGEFKLCDFGVSRELTNSLAMADTF--VGTSMYMSPERIQGLDY 426 Query: 556 SMKSDIYSFGVMVLEIVTG 500 +KSD++S G+M++E+ +G Sbjct: 427 GVKSDVWSTGLMLIELASG 445
>M3K13_PONPY (Q5R8X7) Mitogen-activated protein kinase kinase kinase 13 (EC| 2.7.11.25) Length = 966 Score = 58.5 bits (140), Expect = 2e-08 Identities = 31/80 (38%), Positives = 48/80 (60%) Frame = -2 Query: 736 RIIHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTAYTLKVIGTYGYMSPEYAMDGVF 557 +IIHRD+K+ NVL+ KISDFG ++ T + GT +++PE + Sbjct: 274 KIIHRDLKSPNVLVTHTDAVKISDFGTSKELSDKST---KMSFAGTVAWLAPEVIRNEPV 330 Query: 556 SMKSDIYSFGVMVLEIVTGK 497 S K DI+SFGV++ E++TG+ Sbjct: 331 SEKVDIWSFGVVLWELLTGE 350
>JAK3_HUMAN (P52333) Tyrosine-protein kinase JAK3 (EC 2.7.10.2) (Janus kinase 3)| (JAK-3) (Leukocyte janus kinase) (L-JAK) Length = 1124 Score = 58.2 bits (139), Expect = 3e-08 Identities = 45/153 (29%), Positives = 80/153 (52%), Gaps = 4/153 (2%) Frame = -2 Query: 736 RIIHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTAYTLKVIG--TYGYMSPEYAMDG 563 R +HRD+ A N+L++ KI+DFG+A++ D+ Y ++ G + +PE D Sbjct: 944 RCVHRDLAARNILVESEAHVKIADFGLAKLLPLDK-DYYVVREPGQSPIFWYAPESLSDN 1002 Query: 562 VFSMKSDIYSFGVMVLEIVTGKKNRGFYDAELDLNLLGYAWTLWKEGRSTELLDEA--MM 389 +FS +SD++SFGV++ E+ T AE L ++G + R ELL+E + Sbjct: 1003 IFSRQSDVWSFGVVLYELFTYCDKSCSPSAEF-LRMMGCERDVPALCRLLELLEEGQRLP 1061 Query: 388 GSSCDHSQVRRCIQVALLCVDMNPRNRPLMSSI 290 ++V ++ LC +P++RP S++ Sbjct: 1062 APPACPAEVHELMK---LCWAPSPQDRPSFSAL 1091
>RIPK3_MOUSE (Q9QZL0) Receptor-interacting serine/threonine-protein kinase 3 (EC| 2.7.11.1) (RIP-like protein kinase 3) (Receptor-interacting protein 3) (RIP-3) (mRIP3) Length = 486 Score = 58.2 bits (139), Expect = 3e-08 Identities = 30/86 (34%), Positives = 53/86 (61%), Gaps = 6/86 (6%) Frame = -2 Query: 733 IIHRDMKASNVLLDRNMIPKISDFGIARMFGGDQ----TTAYTLKVIGTYGYMSPE--YA 572 ++HRD+K SN+LLD + K++DFG++ GG Q + + + GT Y+ PE + Sbjct: 139 LLHRDLKPSNILLDPELHAKLADFGLSTFQGGSQSGSGSGSGSRDSGGTLAYLDPELLFK 198 Query: 571 MDGVFSMKSDIYSFGVMVLEIVTGKK 494 ++ S SD+YSFG++V ++ G++ Sbjct: 199 VNLKASKASDVYSFGILVWAVLAGRE 224
>SPKA_SYNY3 (Q9FAB3) Serine/threonine-protein kinase A (EC 2.7.11.1)| Length = 521 Score = 58.2 bits (139), Expect = 3e-08 Identities = 34/83 (40%), Positives = 49/83 (59%), Gaps = 4/83 (4%) Frame = -2 Query: 733 IIHRDMKASNVLLDRNM----IPKISDFGIARMFGGDQTTAYTLKVIGTYGYMSPEYAMD 566 ++HRD+K SNVLL + + KI DFGIA++ + + T +GT Y SPE Sbjct: 144 VVHRDIKPSNVLLVEDPALGELVKILDFGIAKLVQAAEESK-TQAFMGTLAYCSPEQMEG 202 Query: 565 GVFSMKSDIYSFGVMVLEIVTGK 497 +SDIYS GVM+ E++TG+ Sbjct: 203 KELDSRSDIYSLGVMMYEMLTGE 225
>PDPK1_HUMAN (O15530) 3-phosphoinositide-dependent protein kinase 1 (EC| 2.7.11.1) (hPDK1) Length = 556 Score = 58.2 bits (139), Expect = 3e-08 Identities = 27/78 (34%), Positives = 46/78 (58%) Frame = -2 Query: 733 IIHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTAYTLKVIGTYGYMSPEYAMDGVFS 554 IIHRD+K N+LL+ +M +I+DFG A++ + A +GT Y+SPE + Sbjct: 201 IIHRDLKPENILLNEDMHIQITDFGTAKVLSPESKQARANSFVGTAQYVSPELLTEKSAC 260 Query: 553 MKSDIYSFGVMVLEIVTG 500 SD+++ G ++ ++V G Sbjct: 261 KSSDLWALGCIIYQLVAG 278
>NEK11_HUMAN (Q8NG66) Serine/threonine-protein kinase Nek11 (EC 2.7.11.1)| (NimA-related protein kinase 11) (Never in mitosis A-related kinase 11) Length = 645 Score = 58.2 bits (139), Expect = 3e-08 Identities = 33/76 (43%), Positives = 46/76 (60%) Frame = -2 Query: 736 RIIHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTAYTLKVIGTYGYMSPEYAMDGVF 557 RI+HRD+K+ NV L N++ KI DFG++R+ G A TL GT YMSPE + Sbjct: 153 RILHRDLKSKNVFLKNNLL-KIGDFGVSRLLMGSCDLATTL--TGTPHYMSPEALKHQGY 209 Query: 556 SMKSDIYSFGVMVLEI 509 KSDI+S ++ E+ Sbjct: 210 DTKSDIWSLACILYEM 225
>ITK_MOUSE (Q03526) Tyrosine-protein kinase ITK/TSK (EC 2.7.10.2)| (T-cell-specific kinase) (IL-2-inducible T-cell kinase) (Kinase EMT) (Kinase TLK) Length = 625 Score = 58.2 bits (139), Expect = 3e-08 Identities = 44/158 (27%), Positives = 73/158 (46%), Gaps = 5/158 (3%) Frame = -2 Query: 733 IIHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTAYTLKVIGT---YGYMSPEYAMDG 563 +IHRD+ A N L+ N + K+SDFG+ R DQ T+ T GT + SPE Sbjct: 483 VIHRDLAARNCLVGENQVIKVSDFGMTRFVLDDQYTSST----GTKFPVKWASPEVFSFS 538 Query: 562 VFSMKSDIYSFGVMVLEIVTGKKNRGFYDAELDLNLLGYAWTLWKEGRSTELLDEAMMGS 383 +S KSD++SFGV++ E+ + K ++ ++E++++ G Sbjct: 539 RYSSKSDVWSFGVLMWEVFSEGK------------------IPYENRSNSEVVEDISTGF 580 Query: 382 SCDHSQVRRC--IQVALLCVDMNPRNRPLMSSIVMMLA 275 ++ C Q+ C P +RP S ++ LA Sbjct: 581 RLYKPRLASCHVYQIMNHCWKEKPEDRPPFSQLLSQLA 618
>JAK3_RAT (Q63272) Tyrosine-protein kinase JAK3 (EC 2.7.10.2) (Janus kinase 3)| (JAK-3) Length = 1100 Score = 58.2 bits (139), Expect = 3e-08 Identities = 50/160 (31%), Positives = 82/160 (51%), Gaps = 11/160 (6%) Frame = -2 Query: 736 RIIHRDMKASNVLLDRNMIPKISDFGIARM--FGGDQTTAYTLKVIG--TYGYMSPEYAM 569 R +HRD+ A N+L++ KI+DFG+A++ G D Y ++V G + +PE Sbjct: 940 RCVHRDLAARNILVESEAHVKIADFGLAKLLPLGKDY---YVVRVPGQSPIFWYAPESLS 996 Query: 568 DGVFSMKSDIYSFGVMVLEIVTGKKNRGFYDAELDLNLLGYAWTLWKEG----RSTELLD 401 D +FS +SD++SFGV++ E+ T E L ++G +EG ELL Sbjct: 997 DNIFSRQSDVWSFGVVLYELFTYSDKSCSPSTEF-LRMIGPE----REGSPLCHLLELLA 1051 Query: 400 EAMM---GSSCDHSQVRRCIQVALLCVDMNPRNRPLMSSI 290 E S+C ++V+ +Q LC NP++RP ++ Sbjct: 1052 EGRRLPPPSTCP-TEVQELMQ---LCWSPNPQDRPAFDTL 1087
>PDPK1_MOUSE (Q9Z2A0) 3-phosphoinositide-dependent protein kinase 1 (EC| 2.7.11.1) (mPDK1) Length = 559 Score = 58.2 bits (139), Expect = 3e-08 Identities = 27/78 (34%), Positives = 46/78 (58%) Frame = -2 Query: 733 IIHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTAYTLKVIGTYGYMSPEYAMDGVFS 554 IIHRD+K N+LL+ +M +I+DFG A++ + A +GT Y+SPE + Sbjct: 204 IIHRDLKPENILLNEDMHIQITDFGTAKVLSPESKQARANSFVGTAQYVSPELLTEKSAC 263 Query: 553 MKSDIYSFGVMVLEIVTG 500 SD+++ G ++ ++V G Sbjct: 264 KSSDLWALGCIIYQLVAG 281
>CDC2_RANDY (Q9W739) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) Length = 302 Score = 57.8 bits (138), Expect = 4e-08 Identities = 35/92 (38%), Positives = 55/92 (59%), Gaps = 1/92 (1%) Frame = -2 Query: 736 RIIHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTAYTLKVIGTYGYMSPEYAMDGV- 560 R++HRD+K N+L+D + K++DFG+AR F G YT +V+ T Y +PE + V Sbjct: 123 RVLHRDLKPQNLLIDSKGVIKLADFGLARAF-GIPVRVYTHEVV-TLWYRAPEVLLGSVR 180 Query: 559 FSMKSDIYSFGVMVLEIVTGKKNRGFYDAELD 464 +S D++S G + EI + KK D+E+D Sbjct: 181 YSTPVDVWSIGTIFAEIAS-KKPLFHGDSEID 211
>NEK11_MOUSE (Q8C0Q4) Serine/threonine-protein kinase Nek11 (EC 2.7.11.1)| (NimA-related protein kinase 11) (Never in mitosis A-related kinase 11) Length = 628 Score = 57.8 bits (138), Expect = 4e-08 Identities = 32/76 (42%), Positives = 46/76 (60%) Frame = -2 Query: 736 RIIHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTAYTLKVIGTYGYMSPEYAMDGVF 557 RI+HRD+K+ N+ L N++ KI DFG++R+ G A TL GT YMSPE + Sbjct: 154 RILHRDLKSKNIFLKNNLL-KIGDFGVSRLLMGSCELATTL--TGTPHYMSPEALKHQGY 210 Query: 556 SMKSDIYSFGVMVLEI 509 KSDI+S ++ E+ Sbjct: 211 DAKSDIWSLACILYEM 226
>FGFR2_XENLA (Q03364) Fibroblast growth factor receptor 2 precursor (EC| 2.7.10.1) (FGFR-2) Length = 813 Score = 57.8 bits (138), Expect = 4e-08 Identities = 31/78 (39%), Positives = 46/78 (58%) Frame = -2 Query: 736 RIIHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTAYTLKVIGTYGYMSPEYAMDGVF 557 + IHRD+ A NVL+ N + KI+DFG+AR T +M+PE D V+ Sbjct: 611 KCIHRDLAARNVLVTENNVMKIADFGLARDVNNIDYYKKTSNGRLPVKWMAPEALFDRVY 670 Query: 556 SMKSDIYSFGVMVLEIVT 503 + +SD++SFGV++ EI T Sbjct: 671 THQSDVWSFGVLMWEIFT 688
>KOK0_YEAST (Q12236) Probable serine/threonine-protein kinase YOL100W (EC| 2.7.11.1) Length = 1081 Score = 57.8 bits (138), Expect = 4e-08 Identities = 31/88 (35%), Positives = 48/88 (54%), Gaps = 9/88 (10%) Frame = -2 Query: 733 IIHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTA----YTLKV-----IGTYGYMSP 581 IIHRD+K N+LLD M K++DFG A++ + Y L +GT Y+SP Sbjct: 299 IIHRDIKPENILLDGEMKIKLTDFGTAKLLNPTNNSVSKPEYDLSTRSKSFVGTAEYVSP 358 Query: 580 EYAMDGVFSMKSDIYSFGVMVLEIVTGK 497 E D + DI++FG ++ +++ GK Sbjct: 359 ELLNDSFTDYRCDIWAFGCILFQMIAGK 386
>EPHA3_BRARE (O13146) Ephrin type-A receptor 3 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor ZEK1) (EPH-like kinase 1) Length = 981 Score = 57.8 bits (138), Expect = 4e-08 Identities = 27/82 (32%), Positives = 52/82 (63%), Gaps = 3/82 (3%) Frame = -2 Query: 739 LRIIHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTAYTL---KVIGTYGYMSPEYAM 569 + +HRD+ A N+L++RN++ K+SDFG++R+ D AYT K+ + +PE Sbjct: 745 MNYVHRDLAARNILVNRNLVCKVSDFGLSRVLEDDPEAAYTTRGGKI--PIRWTAPEAIT 802 Query: 568 DGVFSMKSDIYSFGVMVLEIVT 503 F+ SD++S+G+++ E+++ Sbjct: 803 YRKFTSASDVWSYGIVMWEVIS 824
>NEK11_MACFA (Q8WNU8) Serine/threonine-protein kinase Nek11 (EC 2.7.11.1)| (NimA-related protein kinase 11) (Never in mitosis A-related kinase 11) Length = 637 Score = 57.8 bits (138), Expect = 4e-08 Identities = 32/76 (42%), Positives = 46/76 (60%) Frame = -2 Query: 736 RIIHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTAYTLKVIGTYGYMSPEYAMDGVF 557 RI+HRD+K+ N+ L N++ KI DFG++R+ G A TL GT YMSPE + Sbjct: 153 RILHRDLKSKNIFLKNNLL-KIGDFGVSRLLMGSCDLATTL--TGTPHYMSPEALKHQGY 209 Query: 556 SMKSDIYSFGVMVLEI 509 KSDI+S ++ E+ Sbjct: 210 DTKSDIWSLACILYEM 225
>FUSED_DROME (P23647) Serine/threonine-protein kinase fused (EC 2.7.11.1)| Length = 805 Score = 57.8 bits (138), Expect = 4e-08 Identities = 31/80 (38%), Positives = 46/80 (57%) Frame = -2 Query: 736 RIIHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTAYTLKVIGTYGYMSPEYAMDGVF 557 RI+HRD+K NVLLD+NM K+ DFG+AR T + GT YM+PE + + Sbjct: 120 RILHRDLKPQNVLLDKNMHAKLCDFGLARNM--TLGTHVLTSIKGTPLYMAPELLAEQPY 177 Query: 556 SMKSDIYSFGVMVLEIVTGK 497 +D++S G + E + G+ Sbjct: 178 DHHADMWSLGCIAYESMAGQ 197
>EPA4A_BRARE (O13148) Ephrin type-A receptor 4a (EC 2.7.10.1) (Tyrosine-protein| kinase receptor ZEK2) (EPH-like kinase 2) (Fragment) Length = 292 Score = 57.8 bits (138), Expect = 4e-08 Identities = 28/86 (32%), Positives = 53/86 (61%), Gaps = 10/86 (11%) Frame = -2 Query: 730 IHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTAYTLK-VIGTY---------GYMSP 581 +HRD+ A N+L++ N++ K+SDFG++R+ D AYT + + GTY + +P Sbjct: 117 VHRDLAARNILVNSNLVCKVSDFGMSRVLEEDPDAAYTTREITGTYQSQGGKIPIRWTAP 176 Query: 580 EYAMDGVFSMKSDIYSFGVMVLEIVT 503 E F+ SD++S+G+++ E+++ Sbjct: 177 EAITYRKFTSASDVWSYGIVMWEVMS 202
>PKNA2_BIFLO (Q8G4G1) Probable serine/threonine-protein kinase pknA2 (EC| 2.7.11.1) Length = 757 Score = 57.8 bits (138), Expect = 4e-08 Identities = 27/79 (34%), Positives = 49/79 (62%) Frame = -2 Query: 733 IIHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTAYTLKVIGTYGYMSPEYAMDGVFS 554 ++HRD+K N+L++ +I+DFG+A+ T + T ++GT Y++PE + + Sbjct: 136 VVHRDIKPENILINDRGHVQITDFGLAKA-ASQATLSSTGMLLGTAAYLAPEMIENNQAT 194 Query: 553 MKSDIYSFGVMVLEIVTGK 497 + D+YS G+M E++TGK Sbjct: 195 AQGDLYSVGIMAWEMLTGK 213
>STK25_HUMAN (O00506) Serine/threonine-protein kinase 25 (EC 2.7.11.1) (Sterile| 20/oxidant stress-response kinase 1) (Ste20/oxidant stress response kinase 1) (SOK-1) (Ste20-like kinase) Length = 426 Score = 57.8 bits (138), Expect = 4e-08 Identities = 30/80 (37%), Positives = 45/80 (56%) Frame = -2 Query: 736 RIIHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTAYTLKVIGTYGYMSPEYAMDGVF 557 R IHRD+KA+NVLL K++DFG+A Q T +GT +M+PE + Sbjct: 135 RKIHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQIKRNTF--VGTPFWMAPEVIKQSAY 192 Query: 556 SMKSDIYSFGVMVLEIVTGK 497 K+DI+S G+ +E+ G+ Sbjct: 193 DFKADIWSLGITAIELAKGE 212
>CDC22_XENLA (P24033) Cell division control protein 2 homolog 2 (EC 2.7.11.22)| (EC 2.7.11.23) (p34 protein kinase 2) Length = 302 Score = 57.4 bits (137), Expect = 5e-08 Identities = 35/91 (38%), Positives = 54/91 (59%), Gaps = 1/91 (1%) Frame = -2 Query: 733 IIHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTAYTLKVIGTYGYMSPEYAMDGV-F 557 ++HRD+K N+L+D + K++DFG+AR F G YT +V+ T Y +PE + V + Sbjct: 124 VLHRDLKPQNLLIDNKGVIKLADFGLARAF-GIPVRVYTHEVV-TLWYRAPEVLLGSVRY 181 Query: 556 SMKSDIYSFGVMVLEIVTGKKNRGFYDAELD 464 S D++S G + EI T KK D+E+D Sbjct: 182 STPVDVWSVGTIFAEIAT-KKPLFHGDSEID 211
>SRK4_SPOLA (P42690) Tyrosine-protein kinase isoform SRK4 (EC 2.7.10.2)| Length = 506 Score = 57.4 bits (137), Expect = 5e-08 Identities = 29/78 (37%), Positives = 51/78 (65%), Gaps = 2/78 (2%) Frame = -2 Query: 730 IHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTAYTLKVIGTY--GYMSPEYAMDGVF 557 IHRD+ A N+L+ + I K++DFG+AR+ + Y K+ + + +PE AM F Sbjct: 356 IHRDLAARNILVGEHKICKVADFGLARVIDEE---IYEAKLGAKFPIKWTAPEAAMYSRF 412 Query: 556 SMKSDIYSFGVMVLEIVT 503 ++KSD++SFG+++ E++T Sbjct: 413 TIKSDVWSFGIVLYEVIT 430
>FLT3_HUMAN (P36888) FL cytokine receptor precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor FLT3) (Stem cell tyrosine kinase 1) (STK-1) (CD135 antigen) Length = 993 Score = 57.4 bits (137), Expect = 5e-08 Identities = 26/74 (35%), Positives = 44/74 (59%) Frame = -2 Query: 730 IHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTAYTLKVIGTYGYMSPEYAMDGVFSM 551 +HRD+ A NVL+ + KI DFG+AR D +M+PE +G++++ Sbjct: 808 VHRDLAARNVLVTHGKVVKICDFGLARDIMSDSNYVVRGNARLPVKWMAPESLFEGIYTI 867 Query: 550 KSDIYSFGVMVLEI 509 KSD++S+G+++ EI Sbjct: 868 KSDVWSYGILLWEI 881
>RMIL_AVII1 (P10533) Serine/threonine-protein kinase transforming protein Rmil| (EC 2.7.11.1) Length = 367 Score = 57.4 bits (137), Expect = 5e-08 Identities = 50/194 (25%), Positives = 88/194 (45%), Gaps = 8/194 (4%) Frame = -2 Query: 733 IIHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTAYTLKVIGTYGYMSPEYAM---DG 563 IIHRD+K++N+ L ++ KI DFG+A + + ++ G+ +M+PE Sbjct: 182 IIHRDLKSNNIFLHEDLTVKIGDFGLATVKSRWSGSHQFEQLSGSILWMAPEVIRMQDKN 241 Query: 562 VFSMKSDIYSFGVMVLEIVTGKKNRGFYDAELDLNLLGYAWTLWKEGRSTELLDEAMMGS 383 +S +SD+Y+FG+++ E++TG+ N+ ++ GR D + + S Sbjct: 242 PYSFQSDVYAFGIVLYELMTGQLPYS--------NINNRDQIIFMVGRGYLSPDLSKVRS 293 Query: 382 SCDHSQVRRCIQVALLCVDMNPRNRPLMSSIVMMLATENATLPE----PNEPGGN-VGKS 218 +C + R + C+ RPL I+ + +LP+ +EP N G Sbjct: 294 NCPKAMKRLMAE----CLKKKRDERPLFPQILASIELLARSLPKIHRSASEPSLNRAGFQ 349 Query: 217 TSDGELSQTQSELT 176 T D L S T Sbjct: 350 TEDFSLYACASPKT 363
>BRAF1_MOUSE (P28028) B-Raf proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (Fragment) Length = 328 Score = 57.4 bits (137), Expect = 5e-08 Identities = 50/194 (25%), Positives = 88/194 (45%), Gaps = 8/194 (4%) Frame = -2 Query: 733 IIHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTAYTLKVIGTYGYMSPEYAM---DG 563 IIHRD+K++N+ L ++ KI DFG+A + + ++ G+ +M+PE Sbjct: 134 IIHRDLKSNNIFLHEDLTVKIGDFGLATVKSRWSGSHQFEQLSGSILWMAPEVIRMQDKN 193 Query: 562 VFSMKSDIYSFGVMVLEIVTGKKNRGFYDAELDLNLLGYAWTLWKEGRSTELLDEAMMGS 383 +S +SD+Y+FG+++ E++TG+ N+ ++ GR D + + S Sbjct: 194 PYSFQSDVYAFGIVLYELMTGQLPYS--------NINNRDQIIFMVGRGYLSPDLSKVRS 245 Query: 382 SCDHSQVRRCIQVALLCVDMNPRNRPLMSSIVMMLATENATLPE----PNEPGGN-VGKS 218 +C + R + C+ RPL I+ + +LP+ +EP N G Sbjct: 246 NCPKAMKRLMAE----CLKKKRDERPLFPQILASIELLARSLPKIHRSASEPSLNRAGFQ 301 Query: 217 TSDGELSQTQSELT 176 T D L S T Sbjct: 302 TEDFSLYACASPKT 315
>PKAA_STRCO (P54739) Serine/threonine protein kinase pkaA (EC 2.7.11.1)| Length = 543 Score = 57.4 bits (137), Expect = 5e-08 Identities = 31/82 (37%), Positives = 50/82 (60%), Gaps = 3/82 (3%) Frame = -2 Query: 733 IIHRDMKASNVLLDRN---MIPKISDFGIARMFGGDQTTAYTLKVIGTYGYMSPEYAMDG 563 ++HRD+K +NVLL + M P ++DFGIAR+ T T + +GT Y++PE A Sbjct: 138 VVHRDLKPANVLLKQTGGEMHPMLTDFGIARLADSPGLTR-THEFVGTPAYVAPESAEGR 196 Query: 562 VFSMKSDIYSFGVMVLEIVTGK 497 + D+Y G+++ E+VTG+ Sbjct: 197 PQTSAVDVYGAGILLYELVTGR 218
>BRAF1_CHICK (Q04982) B-Raf proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (Rmil serine/threonine-protein kinase) (c-Rmil) Length = 806 Score = 57.4 bits (137), Expect = 5e-08 Identities = 50/194 (25%), Positives = 88/194 (45%), Gaps = 8/194 (4%) Frame = -2 Query: 733 IIHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTAYTLKVIGTYGYMSPEYAM---DG 563 IIHRD+K++N+ L ++ KI DFG+A + + ++ G+ +M+PE Sbjct: 612 IIHRDLKSNNIFLHEDLTVKIGDFGLATVKSRWSGSHQFEQLSGSILWMAPEVIRMQDKN 671 Query: 562 VFSMKSDIYSFGVMVLEIVTGKKNRGFYDAELDLNLLGYAWTLWKEGRSTELLDEAMMGS 383 +S +SD+Y+FG+++ E++TG+ N+ ++ GR D + + S Sbjct: 672 PYSFQSDVYAFGIVLYELMTGQLPYS--------NINNRDQIIFMVGRGYLSPDLSKVRS 723 Query: 382 SCDHSQVRRCIQVALLCVDMNPRNRPLMSSIVMMLATENATLPE----PNEPGGN-VGKS 218 +C + R + C+ RPL I+ + +LP+ +EP N G Sbjct: 724 NCPKAMKRLMAE----CLKKKRDERPLFPQILASIELLARSLPKIHRSASEPSLNRAGFQ 779 Query: 217 TSDGELSQTQSELT 176 T D L S T Sbjct: 780 TEDFSLYACASPKT 793
>BRAF1_HUMAN (P15056) B-Raf proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (p94) (v-Raf murine sarcoma viral oncogene homolog B1) Length = 766 Score = 57.4 bits (137), Expect = 5e-08 Identities = 50/194 (25%), Positives = 88/194 (45%), Gaps = 8/194 (4%) Frame = -2 Query: 733 IIHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTAYTLKVIGTYGYMSPEYAM---DG 563 IIHRD+K++N+ L ++ KI DFG+A + + ++ G+ +M+PE Sbjct: 572 IIHRDLKSNNIFLHEDLTVKIGDFGLATVKSRWSGSHQFEQLSGSILWMAPEVIRMQDKN 631 Query: 562 VFSMKSDIYSFGVMVLEIVTGKKNRGFYDAELDLNLLGYAWTLWKEGRSTELLDEAMMGS 383 +S +SD+Y+FG+++ E++TG+ N+ ++ GR D + + S Sbjct: 632 PYSFQSDVYAFGIVLYELMTGQLPYS--------NINNRDQIIFMVGRGYLSPDLSKVRS 683 Query: 382 SCDHSQVRRCIQVALLCVDMNPRNRPLMSSIVMMLATENATLPE----PNEPGGN-VGKS 218 +C + R + C+ RPL I+ + +LP+ +EP N G Sbjct: 684 NCPKAMKRLMAE----CLKKKRDERPLFPQILASIELLARSLPKIHRSASEPSLNRAGFQ 739 Query: 217 TSDGELSQTQSELT 176 T D L S T Sbjct: 740 TEDFSLYACASPKT 753
>M3K2_ARATH (Q9FZ36) Mitogen-activated protein kinase kinase kinase 2 (EC| 2.7.11.25) (Arabidospsis NPK1-related protein kinase 2) Length = 651 Score = 57.4 bits (137), Expect = 5e-08 Identities = 29/79 (36%), Positives = 47/79 (59%) Frame = -2 Query: 733 IIHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTAYTLKVIGTYGYMSPEYAMDGVFS 554 I+HRD+K +N+L+D K++DFG ++ T + + GT +M+PE + S Sbjct: 192 IMHRDIKGANILVDNQGCIKLADFGASKQVAELATISGAKSMKGTPYWMAPEVILQTGHS 251 Query: 553 MKSDIYSFGVMVLEIVTGK 497 +DI+S G V+E+VTGK Sbjct: 252 FSADIWSVGCTVIEMVTGK 270
>CAD96_DROME (Q9VBW3) Tyrosine kinase receptor Cad96Ca precursor (EC 2.7.10.1)| (Cadherin 96Ca) (Tyrosine kinase receptor HD-14) Length = 773 Score = 57.4 bits (137), Expect = 5e-08 Identities = 48/158 (30%), Positives = 76/158 (48%), Gaps = 6/158 (3%) Frame = -2 Query: 733 IIHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTA--YTLKVIGTYG--YMSPEYAMD 566 IIHRD+ A N+L+ + K++DFG AR D T+ Y K G +M+ E D Sbjct: 606 IIHRDLAARNILITDDHTCKVADFGFAR----DVITSKIYERKSEGKLPIRWMATESLYD 661 Query: 565 GVFSMKSDIYSFGVMVLEIVTGKKNRGFYDAELDLNLLGYAWTLWKEGRSTELLDEAMMG 386 +FS+KSDI+SFG+++ EIVT LG T + + +++ + G Sbjct: 662 NIFSVKSDIWSFGILMWEIVT----------------LGS--TPYPGISAADVMRKVRDG 703 Query: 385 SSCDHSQ--VRRCIQVALLCVDMNPRNRPLMSSIVMML 278 + + R + C +P+ RPL + I+ ML Sbjct: 704 YRLEKPEHCRRELYNIMYYCWSHDPQERPLFAEIIQML 741
>RMIL_AVEVR (P27966) Serine/threonine-protein kinase transforming protein Rmil| (EC 2.7.11.1) Length = 450 Score = 57.4 bits (137), Expect = 5e-08 Identities = 50/194 (25%), Positives = 88/194 (45%), Gaps = 8/194 (4%) Frame = -2 Query: 733 IIHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTAYTLKVIGTYGYMSPEYAM---DG 563 IIHRD+K++N+ L ++ KI DFG+A + + ++ G+ +M+PE Sbjct: 198 IIHRDLKSNNIFLHEDLTVKIGDFGLATVKSRWSGSHQFEQLSGSILWMAPEVIRMQDKN 257 Query: 562 VFSMKSDIYSFGVMVLEIVTGKKNRGFYDAELDLNLLGYAWTLWKEGRSTELLDEAMMGS 383 +S +SD+Y+FG+++ E++TG+ N+ ++ GR D + + S Sbjct: 258 PYSFQSDVYAFGIVLYELMTGQLPYS--------NINNRDQIIFMVGRGYLSPDLSKVRS 309 Query: 382 SCDHSQVRRCIQVALLCVDMNPRNRPLMSSIVMMLATENATLPE----PNEPGGN-VGKS 218 +C + R + C+ RPL I+ + +LP+ +EP N G Sbjct: 310 NCPKAMKRLMAE----CLKKKRDERPLFPQILASIELLARSLPKIHRSASEPSLNRAGFQ 365 Query: 217 TSDGELSQTQSELT 176 T D L S T Sbjct: 366 TEDFSLYACASPKT 379
>IRAK3_MOUSE (Q8K4B2) Interleukin-1 receptor-associated kinase 3 (EC 2.7.11.1)| (IRAK-3) (IL-1 receptor-associated kinase M) (IRAK-M) Length = 609 Score = 57.4 bits (137), Expect = 5e-08 Identities = 44/170 (25%), Positives = 77/170 (45%), Gaps = 5/170 (2%) Frame = -2 Query: 733 IIHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTAYTLKVIGT----YGYMSPEYAMD 566 +I ++ ++N+LLD + PK++DF A + + T+ + G YM EY Sbjct: 302 VICGNVSSANILLDDQLQPKLTDFAAAHFRPNLEQQSSTINMTGGGRKHLWYMPEEYIRQ 361 Query: 565 GVFSMKSDIYSFGVMVLEIVTGKKNRGFYDAELDLNLLGYAWTLW-KEGRSTELLDEAMM 389 G S+K+D+YSFG++++E++TG K D + L L K G + L Sbjct: 362 GRLSVKTDVYSFGIVIMEVLTGCK--VVLDDPKHVQLRDLLMELMEKRGLDSCLSFLDRK 419 Query: 388 GSSCDHSQVRRCIQVALLCVDMNPRNRPLMSSIVMMLATENATLPEPNEP 239 C + + +A CV + RP M ++ L + +L +P Sbjct: 420 IPPCPRNFSAKLFSLAGRCVATKAKLRPTMDEVLSSLESTQPSLYFAEDP 469
>FLT3_MOUSE (Q00342) FL cytokine receptor precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor flk-2) (Fetal liver kinase 2) (Tyrosine-protein kinase FLT3) Length = 992 Score = 57.4 bits (137), Expect = 5e-08 Identities = 26/74 (35%), Positives = 45/74 (60%) Frame = -2 Query: 730 IHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTAYTLKVIGTYGYMSPEYAMDGVFSM 551 +HRD+ A NVL+ + KI DFG+AR D + +M+PE +G++++ Sbjct: 811 VHRDLAARNVLVTHGKVVKICDFGLARDILSDSSYVVRGNARLPVKWMAPESLFEGIYTI 870 Query: 550 KSDIYSFGVMVLEI 509 KSD++S+G+++ EI Sbjct: 871 KSDVWSYGILLWEI 884
>CSF1R_MOUSE (P09581) Macrophage colony-stimulating factor 1 receptor precursor| (CSF-1-R) (EC 2.7.10.1) (Fms proto-oncogene) (c-fms) Length = 977 Score = 57.4 bits (137), Expect = 5e-08 Identities = 50/190 (26%), Positives = 75/190 (39%), Gaps = 7/190 (3%) Frame = -2 Query: 730 IHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTAYTLKVIGTYGYMSPEYAMDGVFSM 551 IHRD+ A NVLL + KI DFG+AR D +M+PE D V+++ Sbjct: 773 IHRDVAARNVLLTSGHVAKIGDFGLARDIMNDSNYVVKGNARLPVKWMAPESIFDCVYTV 832 Query: 550 KSDIYSFGVMVLEIVTGKKNRGFYDAELDLNLLGYAWTLWKEGRSTELLDEAMMGSSCDH 371 +SD++S+G+++ EI L L Y L + D M Sbjct: 833 QSDVWSYGILLWEI-------------FSLGLNPYPGILVNNKFYKLVKDGYQMAQPV-- 877 Query: 370 SQVRRCIQVALLCVDMNPRNRPLMSSIVMMLATENATLPEPNE-------PGGNVGKSTS 212 + + C D+ P RP I +L E A L ++ GG+ G + Sbjct: 878 FAPKNIYSIMQSCWDLEPTRRPTFQQICFLL-QEQARLERRDQDYANLPSSGGSSGSDSG 936 Query: 211 DGELSQTQSE 182 G + SE Sbjct: 937 GGSSGGSSSE 946
>HT1_ARATH (Q2MHE4) Serine/threonine-protein kinase HT1 (EC 2.7.11.1) (High| leaf temperature protein 1) Length = 390 Score = 57.4 bits (137), Expect = 5e-08 Identities = 29/78 (37%), Positives = 51/78 (65%), Gaps = 1/78 (1%) Frame = -2 Query: 733 IIHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTAYTLKV-IGTYGYMSPEYAMDGVF 557 +IHRD+K++N+LL+ M K++DFG + + +T K +GTY +M+PE + + Sbjct: 208 VIHRDLKSNNLLLNDEMRVKVADFGTSCL----ETQCREAKGNMGTYRWMAPEMIKEKPY 263 Query: 556 SMKSDIYSFGVMVLEIVT 503 + K D+YSFG+++ E+ T Sbjct: 264 TRKVDVYSFGIVLWELTT 281
>BRAF1_COTJA (P34908) B-Raf proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (RMIL serine/threonine-protein kinase) (c-RMIL) Length = 807 Score = 57.4 bits (137), Expect = 5e-08 Identities = 50/194 (25%), Positives = 88/194 (45%), Gaps = 8/194 (4%) Frame = -2 Query: 733 IIHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTAYTLKVIGTYGYMSPEYAM---DG 563 IIHRD+K++N+ L ++ KI DFG+A + + ++ G+ +M+PE Sbjct: 612 IIHRDLKSNNIFLHEDLTVKIGDFGLATVKSRWSGSHQFEQLSGSILWMAPEVIRMQDKN 671 Query: 562 VFSMKSDIYSFGVMVLEIVTGKKNRGFYDAELDLNLLGYAWTLWKEGRSTELLDEAMMGS 383 +S +SD+Y+FG+++ E++TG+ N+ ++ GR D + + S Sbjct: 672 PYSFQSDVYAFGIVLYELMTGQLPYS--------NINNRDQIIFMVGRGYLSPDLSKVRS 723 Query: 382 SCDHSQVRRCIQVALLCVDMNPRNRPLMSSIVMMLATENATLPE----PNEPGGN-VGKS 218 +C + R + C+ RPL I+ + +LP+ +EP N G Sbjct: 724 NCPKAMKRLMAE----CLKKKRDERPLFPQILASIELLARSLPKIHRSASEPSLNRAGFQ 779 Query: 217 TSDGELSQTQSELT 176 T D L S T Sbjct: 780 TEDFSLYACASPKT 793
>SHK2_SCHPO (Q10056) Serine/threonine-protein kinase shk2 (EC 2.7.11.1)| Length = 589 Score = 57.4 bits (137), Expect = 5e-08 Identities = 29/76 (38%), Positives = 44/76 (57%) Frame = -2 Query: 733 IIHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTAYTLKVIGTYGYMSPEYAMDGVFS 554 IIHRD+K+ NVLLD + KI+DFG T+ +GT +M+PE + Sbjct: 430 IIHRDIKSDNVLLDNSGNIKITDFGFCARLSNRTNKRVTM--VGTPYWMAPEVVKQNEYG 487 Query: 553 MKSDIYSFGVMVLEIV 506 K DI+S G+M++E++ Sbjct: 488 TKVDIWSLGIMIIEMI 503
>STK25_MOUSE (Q9Z2W1) Serine/threonine-protein kinase 25 (EC 2.7.11.1) (Sterile| 20/oxidant stress-response kinase 1) (Ste20/oxidant stress response kinase 1) (SOK-1) (Ste20-like kinase) Length = 426 Score = 57.4 bits (137), Expect = 5e-08 Identities = 30/80 (37%), Positives = 45/80 (56%) Frame = -2 Query: 736 RIIHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTAYTLKVIGTYGYMSPEYAMDGVF 557 R IHRD+KA+NVLL K++DFG+A Q T +GT +M+PE + Sbjct: 135 RKIHRDIKAANVLLSEQGDVKMADFGVAGQLTDTQIKRNTF--VGTPFWMAPEVIKQSAY 192 Query: 556 SMKSDIYSFGVMVLEIVTGK 497 K+DI+S G+ +E+ G+ Sbjct: 193 DFKADIWSLGITAIELAKGE 212
>YL673_MIMIV (Q5UNT1) Putative serine/threonine-protein kinase L673 (EC| 2.7.11.1) Length = 545 Score = 57.0 bits (136), Expect = 6e-08 Identities = 36/92 (39%), Positives = 55/92 (59%), Gaps = 3/92 (3%) Frame = -2 Query: 733 IIHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTAYTLKVIGTYGYMSPEYAMDGVF- 557 I+HRD+ ASN+L+ + + KI DFG AR F GD + + + Y + E M G+F Sbjct: 380 IMHRDLSASNILIKGSTL-KIGDFGSARFFSGDTLDTKYTRNVCSINYRAMELLM-GIFP 437 Query: 556 -SMKSDIYSFGVMVLEIVTGKK-NRGFYDAEL 467 + K DI+S G ++ EI+TGK+ G +AE+ Sbjct: 438 YNNKIDIWSCGCLITEILTGKRIFNGLKEAEV 469
>CDC2_EMENI (Q00646) Cell division control protein 2 (EC 2.7.11.22) (EC| 2.7.11.23) (Cyclin-dependent protein kinase) Length = 323 Score = 57.0 bits (136), Expect = 6e-08 Identities = 34/81 (41%), Positives = 51/81 (62%), Gaps = 1/81 (1%) Frame = -2 Query: 736 RIIHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTAYTLKVIGTYGYMSPEYAMDG-V 560 R++HRD+K N+L+DR+ K++DFG+AR FG T YT +V+ T Y SPE + G Sbjct: 142 RVLHRDLKPQNLLIDRDGNLKLADFGLARAFGVPLRT-YTHEVV-TLWYRSPEILLGGRQ 199 Query: 559 FSMKSDIYSFGVMVLEIVTGK 497 +S D++S G + E+ T K Sbjct: 200 YSTGVDMWSCGAIFAEMCTRK 220
>VGFR2_COTJA (P52583) Vascular endothelial growth factor receptor 2 precursor (EC| 2.7.10.1) (VEGFR-2) (Endothelial kinase receptor EK1) (Quek 1) (Quek1) Length = 1348 Score = 57.0 bits (136), Expect = 6e-08 Identities = 30/76 (39%), Positives = 45/76 (59%) Frame = -2 Query: 736 RIIHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTAYTLKVIGTYGYMSPEYAMDGVF 557 + IHRD+ A N+LL N + KI DFG+AR D +M+PE D V+ Sbjct: 1016 KCIHRDLAARNILLSDNNVVKICDFGLARDIYKDPDYVRKGDARLPLKWMAPETIFDRVY 1075 Query: 556 SMKSDIYSFGVMVLEI 509 +++SD++SFGV++ EI Sbjct: 1076 TIQSDVWSFGVLLWEI 1091
>ROS_HUMAN (P08922) Proto-oncogene tyrosine-protein kinase ROS precursor (EC| 2.7.10.1) (c-ros-1) Length = 2347 Score = 57.0 bits (136), Expect = 6e-08 Identities = 36/106 (33%), Positives = 57/106 (53%), Gaps = 5/106 (4%) Frame = -2 Query: 739 LRIIHRDMKASNVLLDRN-----MIPKISDFGIARMFGGDQTTAYTLKVIGTYGYMSPEY 575 + IHRD+ A N L+ I KI DFG+AR + + + +M+PE Sbjct: 2073 MHFIHRDLAARNCLVSVKDYTSPRIVKIGDFGLARDIYKNDYYRKRGEGLLPVRWMAPES 2132 Query: 574 AMDGVFSMKSDIYSFGVMVLEIVTGKKNRGFYDAELDLNLLGYAWT 437 MDG+F+ +SD++SFG+++ EI+T Y A +L++L Y T Sbjct: 2133 LMDGIFTTQSDVWSFGILIWEILT--LGHQPYPAHSNLDVLNYVQT 2176
>NEK1_HUMAN (Q96PY6) Serine/threonine-protein kinase Nek1 (EC 2.7.11.1)| (NimA-related protein kinase 1) (NY-REN-55 antigen) Length = 1258 Score = 57.0 bits (136), Expect = 6e-08 Identities = 30/80 (37%), Positives = 49/80 (61%) Frame = -2 Query: 736 RIIHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTAYTLKVIGTYGYMSPEYAMDGVF 557 +I+HRD+K+ N+ L ++ ++ DFGIAR+ A T IGT Y+SPE + + Sbjct: 123 KILHRDIKSQNIFLTKDGTVQLGDFGIARVLNSTVELART--CIGTPYYLSPEICENKPY 180 Query: 556 SMKSDIYSFGVMVLEIVTGK 497 + KSDI++ G ++ E+ T K Sbjct: 181 NNKSDIWALGCVLYELCTLK 200
>STK24_MOUSE (Q99KH8) Serine/threonine-protein kinase 24 (EC 2.7.11.1)| Length = 431 Score = 57.0 bits (136), Expect = 6e-08 Identities = 29/78 (37%), Positives = 45/78 (57%) Frame = -2 Query: 730 IHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTAYTLKVIGTYGYMSPEYAMDGVFSM 551 IHRD+KA+NVLL + K++DFG+A Q T +GT +M+PE + Sbjct: 141 IHRDIKAANVLLSEHGEVKLADFGVAGQLTDTQIKRNTF--VGTPFWMAPEVIKQSAYDS 198 Query: 550 KSDIYSFGVMVLEIVTGK 497 K+DI+S G+ +E+ G+ Sbjct: 199 KADIWSLGITAIELAKGE 216
>MKH1_SCHPO (Q10407) MAP kinase kinase kinase mkh1 (EC 2.7.11.25)| Length = 1116 Score = 57.0 bits (136), Expect = 6e-08 Identities = 31/82 (37%), Positives = 51/82 (62%), Gaps = 2/82 (2%) Frame = -2 Query: 733 IIHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTAYTLKVIGTYGYMSPEYAMDG--V 560 IIHRD+KA N+L+D + + KISDFGI++ L + G+ +M+PE + Sbjct: 951 IIHRDLKADNLLIDFDGVCKISDFGISKHSDNVYDNDANLSMQGSIFWMAPEVIHNDHQG 1010 Query: 559 FSMKSDIYSFGVMVLEIVTGKK 494 +S K D++S G +VLE++ G++ Sbjct: 1011 YSAKVDVWSLGCVVLEMLAGRR 1032
>NEK1_MOUSE (P51954) Serine/threonine-protein kinase Nek1 (EC 2.7.11.1)| (NimA-related protein kinase 1) Length = 1203 Score = 57.0 bits (136), Expect = 6e-08 Identities = 30/80 (37%), Positives = 49/80 (61%) Frame = -2 Query: 736 RIIHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTAYTLKVIGTYGYMSPEYAMDGVF 557 +I+HRD+K+ N+ L ++ ++ DFGIAR+ A T IGT Y+SPE + + Sbjct: 123 KILHRDIKSQNIFLTKDGTVQLGDFGIARVLNSTVELART--CIGTPYYLSPEICENKPY 180 Query: 556 SMKSDIYSFGVMVLEIVTGK 497 + KSDI++ G ++ E+ T K Sbjct: 181 NNKSDIWALGCVLYELCTLK 200
>PAK3_RAT (Q62829) Serine/threonine-protein kinase PAK 3 (EC 2.7.11.1)| (p21-activated kinase 3) (PAK-3) (Beta-PAK) (p65-PAK) Length = 544 Score = 57.0 bits (136), Expect = 6e-08 Identities = 28/80 (35%), Positives = 48/80 (60%) Frame = -2 Query: 736 RIIHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTAYTLKVIGTYGYMSPEYAMDGVF 557 ++IHRD+K+ N+LL + K++DFG +Q+ T+ +GT +M+PE + Sbjct: 382 QVIHRDIKSDNILLGMDGSVKLTDFGFCAQITPEQSKRSTM--VGTPYWMAPEVVTRKAY 439 Query: 556 SMKSDIYSFGVMVLEIVTGK 497 K DI+S G+M +E+V G+ Sbjct: 440 GPKVDIWSLGIMAIEMVEGE 459
>PAK2_RAT (Q64303) Serine/threonine-protein kinase PAK 2 (EC 2.7.11.1)| (p21-activated kinase 2) (PAK-2) (Gamma-PAK) (p62-PAK) Length = 524 Score = 57.0 bits (136), Expect = 6e-08 Identities = 29/80 (36%), Positives = 47/80 (58%) Frame = -2 Query: 736 RIIHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTAYTLKVIGTYGYMSPEYAMDGVF 557 ++IHRD+K+ NVLL K++DFG +Q+ T+ +GT +M+PE + Sbjct: 363 QVIHRDIKSDNVLLGMEGSVKLTDFGFCAQITPEQSKRSTM--VGTPYWMAPEVVTRKAY 420 Query: 556 SMKSDIYSFGVMVLEIVTGK 497 K DI+S G+M +E+V G+ Sbjct: 421 GPKVDIWSLGIMAIEMVEGE 440
>PAK2_RABIT (Q29502) Serine/threonine-protein kinase PAK 2 (EC 2.7.11.1)| (p21-activated kinase 2) (PAK-2) (Gamma-PAK) (p21-activated protein kinase I) (PAKI) Length = 524 Score = 57.0 bits (136), Expect = 6e-08 Identities = 29/80 (36%), Positives = 47/80 (58%) Frame = -2 Query: 736 RIIHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTAYTLKVIGTYGYMSPEYAMDGVF 557 ++IHRD+K+ NVLL K++DFG +Q+ T+ +GT +M+PE + Sbjct: 363 QVIHRDIKSDNVLLGMEGSVKLTDFGFCAQITPEQSKRSTM--VGTPYWMAPEVVTRKAY 420 Query: 556 SMKSDIYSFGVMVLEIVTGK 497 K DI+S G+M +E+V G+ Sbjct: 421 GPKVDIWSLGIMAIEMVEGE 440
>PAK2_MOUSE (Q8CIN4) Serine/threonine-protein kinase PAK 2 (EC 2.7.11.1)| (p21-activated kinase 2) (PAK-2) Length = 524 Score = 57.0 bits (136), Expect = 6e-08 Identities = 29/80 (36%), Positives = 47/80 (58%) Frame = -2 Query: 736 RIIHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTAYTLKVIGTYGYMSPEYAMDGVF 557 ++IHRD+K+ NVLL K++DFG +Q+ T+ +GT +M+PE + Sbjct: 363 QVIHRDIKSDNVLLGMEGSVKLTDFGFCAQITPEQSKRSTM--VGTPYWMAPEVVTRKAY 420 Query: 556 SMKSDIYSFGVMVLEIVTGK 497 K DI+S G+M +E+V G+ Sbjct: 421 GPKVDIWSLGIMAIEMVEGE 440
>PAK2_HUMAN (Q13177) Serine/threonine-protein kinase PAK 2 (EC 2.7.11.1)| (p21-activated kinase 2) (PAK-2) (PAK65) (Gamma-PAK) (S6/H4 kinase) Length = 524 Score = 57.0 bits (136), Expect = 6e-08 Identities = 29/80 (36%), Positives = 47/80 (58%) Frame = -2 Query: 736 RIIHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTAYTLKVIGTYGYMSPEYAMDGVF 557 ++IHRD+K+ NVLL K++DFG +Q+ T+ +GT +M+PE + Sbjct: 363 QVIHRDIKSDNVLLGMEGSVKLTDFGFCAQITPEQSKRSTM--VGTPYWMAPEVVTRKAY 420 Query: 556 SMKSDIYSFGVMVLEIVTGK 497 K DI+S G+M +E+V G+ Sbjct: 421 GPKVDIWSLGIMAIEMVEGE 440
>HIPPO_DROME (Q8T0S6) Serine/threonine-protein kinase hippo (EC 2.7.11.1)| Length = 669 Score = 57.0 bits (136), Expect = 6e-08 Identities = 33/84 (39%), Positives = 48/84 (57%) Frame = -2 Query: 736 RIIHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTAYTLKVIGTYGYMSPEYAMDGVF 557 R IHRD+KA+N+LL+ K++DFG+A T A VIGT +M+PE + + Sbjct: 156 RKIHRDIKAANILLNTEGYAKLADFGVAGQL--TDTMAKRNTVIGTPFWMAPEVIEEIGY 213 Query: 556 SMKSDIYSFGVMVLEIVTGKKNRG 485 +DI+S G+ LE+ GK G Sbjct: 214 DCVADIWSLGITALEMAEGKPPYG 237
>M3K1_ARATH (O22040) Mitogen-activated protein kinase kinase kinase 1 (EC| 2.7.11.25) (Arabidospsis NPK1-related protein kinase 1) Length = 666 Score = 57.0 bits (136), Expect = 6e-08 Identities = 29/79 (36%), Positives = 46/79 (58%) Frame = -2 Query: 733 IIHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTAYTLKVIGTYGYMSPEYAMDGVFS 554 I+HRD+K +N+L+D K++DFG ++ T + GT +M+PE + S Sbjct: 193 IMHRDIKGANILVDNKGCIKLADFGASKQVAELATMTGAKSMKGTPYWMAPEVILQTGHS 252 Query: 553 MKSDIYSFGVMVLEIVTGK 497 +DI+S G V+E+VTGK Sbjct: 253 FSADIWSVGCTVIEMVTGK 271
>PAK3_PONPY (Q7YQL3) Serine/threonine-protein kinase PAK 3 (EC 2.7.11.1)| (p21-activated kinase 3) (PAK-3) Length = 559 Score = 57.0 bits (136), Expect = 6e-08 Identities = 28/80 (35%), Positives = 48/80 (60%) Frame = -2 Query: 736 RIIHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTAYTLKVIGTYGYMSPEYAMDGVF 557 ++IHRD+K+ N+LL + K++DFG +Q+ T+ +GT +M+PE + Sbjct: 397 QVIHRDIKSDNILLGMDGSVKLTDFGFCAQITPEQSKRSTM--VGTPYWMAPEVVTRKAY 454 Query: 556 SMKSDIYSFGVMVLEIVTGK 497 K DI+S G+M +E+V G+ Sbjct: 455 GPKVDIWSLGIMAIEMVEGE 474
>PAK3_PANTR (Q7YQL4) Serine/threonine-protein kinase PAK 3 (EC 2.7.11.1)| (p21-activated kinase 3) (PAK-3) Length = 559 Score = 57.0 bits (136), Expect = 6e-08 Identities = 28/80 (35%), Positives = 48/80 (60%) Frame = -2 Query: 736 RIIHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTAYTLKVIGTYGYMSPEYAMDGVF 557 ++IHRD+K+ N+LL + K++DFG +Q+ T+ +GT +M+PE + Sbjct: 397 QVIHRDIKSDNILLGMDGSVKLTDFGFCAQITPEQSKRSTM--VGTPYWMAPEVVTRKAY 454 Query: 556 SMKSDIYSFGVMVLEIVTGK 497 K DI+S G+M +E+V G+ Sbjct: 455 GPKVDIWSLGIMAIEMVEGE 474
>PAK3_MOUSE (Q61036) Serine/threonine-protein kinase PAK 3 (EC 2.7.11.1)| (p21-activated kinase 3) (PAK-3) (Beta-PAK) (CDC42/RAC effector kinase PAK-B) Length = 559 Score = 57.0 bits (136), Expect = 6e-08 Identities = 28/80 (35%), Positives = 48/80 (60%) Frame = -2 Query: 736 RIIHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTAYTLKVIGTYGYMSPEYAMDGVF 557 ++IHRD+K+ N+LL + K++DFG +Q+ T+ +GT +M+PE + Sbjct: 397 QVIHRDIKSDNILLGMDGSVKLTDFGFCAQITPEQSKRSTM--VGTPYWMAPEVVTRKAY 454 Query: 556 SMKSDIYSFGVMVLEIVTGK 497 K DI+S G+M +E+V G+ Sbjct: 455 GPKVDIWSLGIMAIEMVEGE 474
>PAK3_HUMAN (O75914) Serine/threonine-protein kinase PAK 3 (EC 2.7.11.1)| (p21-activated kinase 3) (PAK-3) (Beta-PAK) (Oligophrenin-3) Length = 559 Score = 57.0 bits (136), Expect = 6e-08 Identities = 28/80 (35%), Positives = 48/80 (60%) Frame = -2 Query: 736 RIIHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTAYTLKVIGTYGYMSPEYAMDGVF 557 ++IHRD+K+ N+LL + K++DFG +Q+ T+ +GT +M+PE + Sbjct: 397 QVIHRDIKSDNILLGMDGSVKLTDFGFCAQITPEQSKRSTM--VGTPYWMAPEVVTRKAY 454 Query: 556 SMKSDIYSFGVMVLEIVTGK 497 K DI+S G+M +E+V G+ Sbjct: 455 GPKVDIWSLGIMAIEMVEGE 474
>EPHA8_MOUSE (O09127) Ephrin type-A receptor 8 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EEK) (EPH- and ELK-related kinase) Length = 1004 Score = 57.0 bits (136), Expect = 6e-08 Identities = 32/81 (39%), Positives = 48/81 (59%), Gaps = 3/81 (3%) Frame = -2 Query: 739 LRIIHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTAYTL---KVIGTYGYMSPEYAM 569 L IHRD+ A NVL+D ++ K+SDFG++R D AYT K+ + +PE Sbjct: 753 LGYIHRDLAARNVLVDGRLVCKVSDFGLSRALEDDPEAAYTTAGGKI--PIRWTAPEAIA 810 Query: 568 DGVFSMKSDIYSFGVMVLEIV 506 FS SD++SFGV++ E++ Sbjct: 811 FRTFSSASDVWSFGVVMWEVL 831
>STK24_HUMAN (Q9Y6E0) Serine/threonine-protein kinase 24 (EC 2.7.11.1)| (STE20-like kinase MST3) (MST-3) (Mammalian STE20-like protein kinase 3) Length = 443 Score = 57.0 bits (136), Expect = 6e-08 Identities = 29/78 (37%), Positives = 45/78 (57%) Frame = -2 Query: 730 IHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTAYTLKVIGTYGYMSPEYAMDGVFSM 551 IHRD+KA+NVLL + K++DFG+A Q T +GT +M+PE + Sbjct: 153 IHRDIKAANVLLSEHGEVKLADFGVAGQLTDTQIKRNTF--VGTPFWMAPEVIKQSAYDS 210 Query: 550 KSDIYSFGVMVLEIVTGK 497 K+DI+S G+ +E+ G+ Sbjct: 211 KADIWSLGITAIELARGE 228
>MST4_MOUSE (Q99JT2) Serine/threonine-protein kinase MST4 (EC 2.7.11.1)| (STE20-like kinase MST4) (MST-4) (Mammalian STE20-like protein kinase 4) Length = 416 Score = 57.0 bits (136), Expect = 6e-08 Identities = 29/78 (37%), Positives = 44/78 (56%) Frame = -2 Query: 730 IHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTAYTLKVIGTYGYMSPEYAMDGVFSM 551 IHRD+KA+NVLL K++DFG+A Q T +GT +M+PE + Sbjct: 141 IHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQIKRNTF--VGTPFWMAPEVIQQSAYDS 198 Query: 550 KSDIYSFGVMVLEIVTGK 497 K+DI+S G+ +E+ G+ Sbjct: 199 KADIWSLGITAIELAKGE 216
>MST4_HUMAN (Q9P289) Serine/threonine-protein kinase MST4 (EC 2.7.11.1)| (STE20-like kinase MST4) (MST-4) (Mammalian STE20-like protein kinase 4) (Serine/threonine-protein kinase MASK) (Mst3 and SOK1-related kinase) Length = 416 Score = 57.0 bits (136), Expect = 6e-08 Identities = 29/78 (37%), Positives = 44/78 (56%) Frame = -2 Query: 730 IHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTAYTLKVIGTYGYMSPEYAMDGVFSM 551 IHRD+KA+NVLL K++DFG+A Q T +GT +M+PE + Sbjct: 141 IHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQIKRNTF--VGTPFWMAPEVIQQSAYDS 198 Query: 550 KSDIYSFGVMVLEIVTGK 497 K+DI+S G+ +E+ G+ Sbjct: 199 KADIWSLGITAIELAKGE 216
>PAK1_MOUSE (O88643) Serine/threonine-protein kinase PAK 1 (EC 2.7.11.1)| (p21-activated kinase 1) (PAK-1) (P65-PAK) (Alpha-PAK) (CDC42/RAC effector kinase PAK-A) Length = 545 Score = 56.6 bits (135), Expect = 8e-08 Identities = 27/80 (33%), Positives = 48/80 (60%) Frame = -2 Query: 736 RIIHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTAYTLKVIGTYGYMSPEYAMDGVF 557 ++IHRD+K+ N+LL + K++DFG +Q+ T+ +GT +M+PE + Sbjct: 384 QVIHRDIKSDNILLGMDGSVKLTDFGFCAQITPEQSKRSTM--VGTPYWMAPEVVTRKAY 441 Query: 556 SMKSDIYSFGVMVLEIVTGK 497 K DI+S G+M +E++ G+ Sbjct: 442 GPKVDIWSLGIMAIEMIEGE 461
>PAK1_HUMAN (Q13153) Serine/threonine-protein kinase PAK 1 (EC 2.7.11.1)| (p21-activated kinase 1) (PAK-1) (P65-PAK) (Alpha-PAK) Length = 545 Score = 56.6 bits (135), Expect = 8e-08 Identities = 27/80 (33%), Positives = 48/80 (60%) Frame = -2 Query: 736 RIIHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTAYTLKVIGTYGYMSPEYAMDGVF 557 ++IHRD+K+ N+LL + K++DFG +Q+ T+ +GT +M+PE + Sbjct: 384 QVIHRDIKSDNILLGMDGSVKLTDFGFCAQITPEQSKRSTM--VGTPYWMAPEVVTRKAY 441 Query: 556 SMKSDIYSFGVMVLEIVTGK 497 K DI+S G+M +E++ G+ Sbjct: 442 GPKVDIWSLGIMAIEMIEGE 461
>CDC2_CARAU (P51958) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1) Length = 302 Score = 56.6 bits (135), Expect = 8e-08 Identities = 34/92 (36%), Positives = 54/92 (58%), Gaps = 1/92 (1%) Frame = -2 Query: 736 RIIHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTAYTLKVIGTYGYMSPEYAMDGV- 560 R++HRD+K N+L+D + K++DFG+AR F G YT +V+ T Y +PE + Sbjct: 123 RVLHRDLKPQNLLIDNKGVIKLADFGLARAF-GVPVRVYTHEVV-TLWYRAPEVLLGASR 180 Query: 559 FSMKSDIYSFGVMVLEIVTGKKNRGFYDAELD 464 +S D++S G + E+ T KK D+E+D Sbjct: 181 YSTPVDVWSIGTIFAELAT-KKPLFHGDSEID 211
>PTK6_HUMAN (Q13882) Tyrosine-protein kinase 6 (EC 2.7.10.2) (Breast tumor| kinase) (Tyrosine-protein kinase BRK) Length = 451 Score = 56.6 bits (135), Expect = 8e-08 Identities = 27/74 (36%), Positives = 46/74 (62%) Frame = -2 Query: 730 IHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTAYTLKVIGTYGYMSPEYAMDGVFSM 551 IHRD+ A N+L+ N + K+ DFG+AR+ D ++ + Y + +PE G +S Sbjct: 309 IHRDLAARNILVGENTLCKVGDFGLARLIKEDVYLSHDHNI--PYKWTAPEALSRGHYST 366 Query: 550 KSDIYSFGVMVLEI 509 KSD++SFG+++ E+ Sbjct: 367 KSDVWSFGILLHEM 380
>EPHA8_RAT (P29321) Ephrin type-A receptor 8 (EC 2.7.10.1) (Tyrosine-protein| kinase receptor EEK) (EPH- and ELK-related kinase) (Fragment) Length = 372 Score = 56.6 bits (135), Expect = 8e-08 Identities = 31/81 (38%), Positives = 48/81 (59%), Gaps = 3/81 (3%) Frame = -2 Query: 739 LRIIHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTAYTL---KVIGTYGYMSPEYAM 569 L IHRD+ A N+L+D ++ K+SDFG++R D AYT K+ + +PE Sbjct: 121 LGYIHRDLAARNILVDGRLVCKVSDFGLSRALEDDPEAAYTTAGGKI--PIRWTAPEAIA 178 Query: 568 DGVFSMKSDIYSFGVMVLEIV 506 FS SD++SFGV++ E++ Sbjct: 179 FRTFSSASDVWSFGVVMWEVL 199
>VGFR1_MOUSE (P35969) Vascular endothelial growth factor receptor 1 precursor (EC| 2.7.10.1) (VEGFR-1) (Tyrosine-protein kinase receptor FLT) (FLT-1) (Embryonic receptor kinase 2) Length = 1333 Score = 56.6 bits (135), Expect = 8e-08 Identities = 30/76 (39%), Positives = 44/76 (57%) Frame = -2 Query: 736 RIIHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTAYTLKVIGTYGYMSPEYAMDGVF 557 + IHRD+ A N+LL N + KI DFG+AR + +M+PE D V+ Sbjct: 1017 KCIHRDLAARNILLSENNVVKICDFGLARDIYKNPDYVRRGDTRLPLKWMAPESIFDKVY 1076 Query: 556 SMKSDIYSFGVMVLEI 509 S KSD++S+GV++ EI Sbjct: 1077 STKSDVWSYGVLLWEI 1092
>STK4_HUMAN (Q13043) Serine/threonine-protein kinase 4 (EC 2.7.11.1)| (STE20-like kinase MST1) (MST-1) (Mammalian STE20-like protein kinase 1) (Serine/threonine-protein kinase Krs-2) Length = 487 Score = 56.6 bits (135), Expect = 8e-08 Identities = 31/81 (38%), Positives = 48/81 (59%) Frame = -2 Query: 739 LRIIHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTAYTLKVIGTYGYMSPEYAMDGV 560 +R IHRD+KA N+LL+ K++DFG+A T A VIGT +M+PE + Sbjct: 143 MRKIHRDIKAGNILLNTEGHAKLADFGVAGQL--TDTMAKRNTVIGTPFWMAPEVIQEIG 200 Query: 559 FSMKSDIYSFGVMVLEIVTGK 497 ++ +DI+S G+ +E+ GK Sbjct: 201 YNCVADIWSLGITAIEMAEGK 221
>ITK_HUMAN (Q08881) Tyrosine-protein kinase ITK/TSK (EC 2.7.10.2)| (T-cell-specific kinase) (Tyrosine-protein kinase Lyk) (Kinase EMT) Length = 620 Score = 56.6 bits (135), Expect = 8e-08 Identities = 33/83 (39%), Positives = 48/83 (57%), Gaps = 3/83 (3%) Frame = -2 Query: 733 IIHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTAYTLKVIGT---YGYMSPEYAMDG 563 +IHRD+ A N L+ N + K+SDFG+ R DQ T+ T GT + SPE Sbjct: 478 VIHRDLAARNCLVGENQVIKVSDFGMTRFVLDDQYTSST----GTKFPVKWASPEVFSFS 533 Query: 562 VFSMKSDIYSFGVMVLEIVTGKK 494 +S KSD++SFGV++ E+ + K Sbjct: 534 RYSSKSDVWSFGVLMWEVFSEGK 556
>DAF4_CAEEL (P50488) Cell-surface receptor daf-4 precursor (EC 2.7.11.30)| (Abnormal dauer formation protein 4) Length = 744 Score = 56.6 bits (135), Expect = 8e-08 Identities = 31/86 (36%), Positives = 51/86 (59%), Gaps = 6/86 (6%) Frame = -2 Query: 733 IIHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTAYTLKVIGTYGYMSPEYAMDGVFS 554 IIHRD+K+ N+L+ +M I+DFG+AR++ D + L +GT YMSPE ++G Sbjct: 436 IIHRDIKSKNILVKSDMTTCIADFGLARIYSYDIEQSDLLGQVGTKRYMSPE-MLEGATE 494 Query: 553 M------KSDIYSFGVMVLEIVTGKK 494 D+YS G+++ E+++ K Sbjct: 495 FTPTAFKAMDVYSMGLVMWEVISRTK 520
>PAK1_RAT (P35465) Serine/threonine-protein kinase PAK 1 (EC 2.7.11.1)| (p21-activated kinase 1) (PAK-1) (P68-PAK) (Alpha-PAK) (Protein kinase MUK2) Length = 544 Score = 56.6 bits (135), Expect = 8e-08 Identities = 27/80 (33%), Positives = 48/80 (60%) Frame = -2 Query: 736 RIIHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTAYTLKVIGTYGYMSPEYAMDGVF 557 ++IHRD+K+ N+LL + K++DFG +Q+ T+ +GT +M+PE + Sbjct: 383 QVIHRDIKSDNILLGMDGSVKLTDFGFCAQITPEQSKRSTM--VGTPYWMAPEVVTRKAY 440 Query: 556 SMKSDIYSFGVMVLEIVTGK 497 K DI+S G+M +E++ G+ Sbjct: 441 GPKVDIWSLGIMAIEMIEGE 460
>KYK1_DICDI (P18160) Non-receptor tyrosine kinase spore lysis A (EC 2.7.10.2)| (Tyrosine-protein kinase 1) Length = 1584 Score = 56.6 bits (135), Expect = 8e-08 Identities = 31/90 (34%), Positives = 51/90 (56%), Gaps = 13/90 (14%) Frame = -2 Query: 733 IIHRDMKASNVLLDRNMIPK-------------ISDFGIARMFGGDQTTAYTLKVIGTYG 593 I+HRD+ + N+LLD N+ PK ISDFG++R+ + + + +G Sbjct: 1413 ILHRDLSSRNILLDHNIDPKNPVVSSRQDIKCKISDFGLSRL--KKEQASQMTQSVGCIP 1470 Query: 592 YMSPEYAMDGVFSMKSDIYSFGVMVLEIVT 503 YM+PE S KSD+YS+G+++ E++T Sbjct: 1471 YMAPEVFKGDSNSEKSDVYSYGMVLFELLT 1500
>CLA4_YEAST (P48562) Serine/threonine-protein kinase CLA4 (EC 2.7.11.1)| Length = 842 Score = 56.6 bits (135), Expect = 8e-08 Identities = 29/79 (36%), Positives = 46/79 (58%) Frame = -2 Query: 733 IIHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTAYTLKVIGTYGYMSPEYAMDGVFS 554 IIHRD+K+ NVLLD KI+DFG ++ T+ +GT +M+PE + Sbjct: 689 IIHRDIKSDNVLLDTRARVKITDFGFCARLTDKRSKRATM--VGTPYWMAPEVVKQREYD 746 Query: 553 MKSDIYSFGVMVLEIVTGK 497 K D++S G+M +E++ G+ Sbjct: 747 EKIDVWSLGIMTIEMLEGE 765
>INSR_XENLA (Q9PVZ4) Insulin receptor precursor (EC 2.7.10.1) (IR) (Xe-InsR)| (XTK-1b) [Contains: Insulin receptor alpha subunit; Insulin receptor beta subunit] Length = 1362 Score = 56.6 bits (135), Expect = 8e-08 Identities = 44/155 (28%), Positives = 69/155 (44%), Gaps = 2/155 (1%) Frame = -2 Query: 736 RIIHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTAYTLKVIGTYGYMSPEYAMDGVF 557 + +HRD+ A N ++ + KI DFG+ R K + +MSPE DGVF Sbjct: 1143 KFVHRDLAARNCMVADDYAVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMSPESLKDGVF 1202 Query: 556 SMKSDIYSFGVMVLEIVTGKKNRGFYDAELDLNLLGYAWTLWKEGRSTELLDEAMMGSSC 377 + SD++SFGV++ EI + A ++ + ++L M G S Sbjct: 1203 TAFSDVWSFGVVLWEITS------------------LAEQPYQGLSNEQVLKFVMDGGSL 1244 Query: 376 DHSQ--VRRCIQVALLCVDMNPRNRPLMSSIVMML 278 DH + R + +C NP+ RP I+ ML Sbjct: 1245 DHPENCPPRLHSLMQMCWQYNPKMRPTFLEIIDML 1279
>VGFR1_RAT (P53767) Vascular endothelial growth factor receptor 1 precursor (EC| 2.7.10.1) (VEGFR-1) (Tyrosine-protein kinase receptor FLT) (FLT-1) Length = 1336 Score = 56.6 bits (135), Expect = 8e-08 Identities = 30/76 (39%), Positives = 44/76 (57%) Frame = -2 Query: 736 RIIHRDMKASNVLLDRNMIPKISDFGIARMFGGDQTTAYTLKVIGTYGYMSPEYAMDGVF 557 + IHRD+ A N+LL N + KI DFG+AR + +M+PE D V+ Sbjct: 1017 KCIHRDLAARNILLSENNVVKICDFGLARDIYKNPDYVRRGDTRLPLKWMAPESIFDKVY 1076 Query: 556 SMKSDIYSFGVMVLEI 509 S KSD++S+GV++ EI Sbjct: 1077 STKSDVWSYGVLLWEI 1092 Database: uniprot_sprot.fasta Posted date: May 25, 2006 5:36 PM Number of letters in database: 80,573,946 Number of sequences in database: 219,361 Lambda K H 0.318 0.135 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 110,141,444 Number of Sequences: 219361 Number of extensions: 2351916 Number of successful extensions: 8424 Number of sequences better than 10.0: 500 Number of HSP's better than 10.0 without gapping: 6932 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 7328 length of database: 80,573,946 effective HSP length: 109 effective length of database: 56,663,597 effective search space used: 7762912789 frameshift window, decay const: 50, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
