Clone Name	rbasd13i20
Clone Library Name	barley_pub

---

No.	Definition	Score (bits)	E Value
1	GYAR_PYRAB (Q9UYR1) Glyoxylate reductase (EC 1.1.1.26) (Glycolat...	95	2e-19
2	GYAR_PYRHO (O58320) Glyoxylate reductase (EC 1.1.1.26) (Glycolat...	89	2e-17
3	GYAR_PYRKO (Q5JEZ2) Glyoxylate reductase (EC 1.1.1.26) (Glycolat...	87	4e-17
4	GYAR_PYRFU (Q8U3Y2) Glyoxylate reductase (EC 1.1.1.26) (Glycolat...	87	5e-17
5	Y1556_HAEIN (P45250) Putative 2-hydroxyacid dehydrogenase HI1556...	84	5e-16
6	GRHPR_MOUSE (Q91Z53) Glyoxylate reductase/hydroxypyruvate reduct...	82	2e-15
7	FDH_ARATH (Q9S7E4) Formate dehydrogenase, mitochondrial precurso...	82	2e-15
8	GRHPR_HUMAN (Q9UBQ7) Glyoxylate reductase/hydroxypyruvate reduct...	81	3e-15
9	DHGY_METEX (Q59516) Glycerate dehydrogenase (EC 1.1.1.29) (NADH-...	80	4e-15
10	VANH_ENTFC (Q05709) D-specific alpha-keto acid dehydrogenase (EC...	80	8e-15
11	YCDW_ECOLI (P75913) Putative 2-hydroxyacid dehydrogenase ycdW (E...	79	1e-14
12	GYAR_THELI (Q9C4M5) Glyoxylate reductase (EC 1.1.1.26) (Glycolat...	79	2e-14
13	SERA_ARCFU (O29445) D-3-phosphoglycerate dehydrogenase (EC 1.1.1...	77	5e-14
14	FDH_PSESR (P33160) Formate dehydrogenase (EC 1.2.1.2) (NAD-depen...	76	8e-14
15	FDH2_ORYSA (Q67U69) Formate dehydrogenase 2, mitochondrial precu...	76	8e-14
16	SERA_BACSU (P35136) D-3-phosphoglycerate dehydrogenase (EC 1.1.1...	75	1e-13
17	FDH_SOLTU (Q07511) Formate dehydrogenase, mitochondrial precurso...	75	2e-13
18	FDH_HORVU (Q9ZRI8) Formate dehydrogenase, mitochondrial precurso...	75	2e-13
19	YPRB2_CORML (P0C1E9) Hypothetical protein in proB 3'region (EC 1...	75	2e-13
20	FDH1_ORYSA (Q9SXP2) Formate dehydrogenase 1, mitochondrial precu...	74	3e-13
21	GYAR_AERPE (Q9YAW4) Glyoxylate reductase (EC 1.1.1.26) (Glycolat...	74	5e-13
22	Y2355_CORGL (P0C1E8) Hypothetical protein Cgl2355/cg2587 (EC 1.-...	74	5e-13
23	SERA_METJA (Q58424) D-3-phosphoglycerate dehydrogenase (EC 1.1.1...	74	5e-13
24	SERA_METTH (O27051) D-3-phosphoglycerate dehydrogenase (EC 1.1.1...	73	9e-13
25	SERA_MYCLE (O33116) D-3-phosphoglycerate dehydrogenase (EC 1.1.1...	71	3e-12
26	VANH_ENTFA (Q47748) D-specific alpha-keto acid dehydrogenase (EC...	70	6e-12
27	SERA_MYCTU (P0A544) D-3-phosphoglycerate dehydrogenase (EC 1.1.1...	69	1e-11
28	SERA_MYCBO (P0A545) D-3-phosphoglycerate dehydrogenase (EC 1.1.1...	69	1e-11
29	SERA_SHIFL (P0A9T3) D-3-phosphoglycerate dehydrogenase (EC 1.1.1...	69	2e-11
30	SERA_ECOLI (P0A9T0) D-3-phosphoglycerate dehydrogenase (EC 1.1.1...	69	2e-11
31	SERA_ECOL6 (P0A9T1) D-3-phosphoglycerate dehydrogenase (EC 1.1.1...	69	2e-11
32	SERA_ECO57 (P0A9T2) D-3-phosphoglycerate dehydrogenase (EC 1.1.1...	69	2e-11
33	CTBP2_MOUSE (P56546) C-terminal-binding protein 2 (CtBP2)	66	9e-11
34	CTBP2_HUMAN (P56545) C-terminal-binding protein 2 (CtBP2)	66	9e-11
35	TKRA_BACSU (O32264) Probable 2-ketogluconate reductase (EC 1.1.1...	65	1e-10
36	SERA_SYNY3 (P73821) D-3-phosphoglycerate dehydrogenase (EC 1.1.1...	65	2e-10
37	TKRA_ENTAG (P58000) 2-ketogluconate reductase (EC 1.1.1.215) (2K...	65	3e-10
38	PTXD_PSEST (O69054) Phosphonate dehydrogenase (EC 1.20.1.1) (NAD...	64	3e-10
39	FDH_NEUCR (Q07103) Formate dehydrogenase (EC 1.2.1.2) (NAD-depen...	64	3e-10
40	TKRA_ECOLI (P37666) 2-ketogluconate reductase (EC 1.1.1.215) (2K...	64	4e-10
41	TKRA_ECO57 (P58220) 2-ketogluconate reductase (EC 1.1.1.215) (2K...	64	4e-10
42	SERA_ARATH (O04130) D-3-phosphoglycerate dehydrogenase, chloropl...	64	6e-10
43	CTBPB_XENLA (Q9W758) C-terminal-binding protein B (TCF-3 corepre...	63	7e-10
44	CTBP1_MOUSE (O88712) C-terminal-binding protein 1 (EC 1.1.1.-) (...	63	7e-10
45	CTBP1_RAT (Q9Z2F5) C-terminal-binding protein 1 (EC 1.1.1.-) (Ct...	63	7e-10
46	DHGY_CUCSA (P13443) Glycerate dehydrogenase (EC 1.1.1.29) (NADH-...	63	1e-09
47	CTBP1_HUMAN (Q13363) C-terminal-binding protein 1 (EC 1.1.1.-) (...	63	1e-09
48	LDHD_STRP1 (Q99ZM2) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH...	62	1e-09
49	CTBPA_XENLA (Q9YHU0) C-terminal-binding protein A (CtBP)	62	2e-09
50	DHD2_LACPA (P17584) D-2-hydroxyisocaproate dehydrogenase (EC 1.1...	61	4e-09
51	LDHD_TREPA (O83080) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH...	60	5e-09
52	YGDH_SCHPO (O94574) Putative 2-hydroxyacid dehydrogenase C1773.1...	60	6e-09
53	LDHD_LACHE (P30901) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH...	59	1e-08
54	SERA_HAEIN (P43885) D-3-phosphoglycerate dehydrogenase (EC 1.1.1...	59	1e-08
55	CTBP_DROME (O46036) C-terminal-binding protein (CtBP protein) (d...	59	2e-08
56	DDH_ZYMMO (P30799) 2-hydroxyacid dehydrogenase homolog (EC 1.1.1.-)	59	2e-08
57	SERA_SCHPO (P87228) Putative D-3-phosphoglycerate dehydrogenase ...	59	2e-08
58	LDHD_STRA5 (Q8E0N5) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH...	58	2e-08
59	FDH2_YEAST (Q08987) Formate dehydrogenase 2 (EC 1.2.1.2) (NAD-de...	58	3e-08
60	LDHD_LACDE (P26297) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH...	57	5e-08
61	SERA_RAT (O08651) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.9...	57	7e-08
62	SERA_MOUSE (Q61753) D-3-phosphoglycerate dehydrogenase (EC 1.1.1...	57	7e-08
63	SERA_MACFA (Q60HD7) D-3-phosphoglycerate dehydrogenase (EC 1.1.1...	57	7e-08
64	SERA_HUMAN (O43175) D-3-phosphoglycerate dehydrogenase (EC 1.1.1...	57	7e-08
65	LDHD_PEDAC (Q59642) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH...	57	7e-08
66	LDHD_STRA3 (Q8E6A9) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH...	57	7e-08
67	FDH1_YEAST (Q08911) Formate dehydrogenase 1 (EC 1.2.1.2) (NAD-de...	56	1e-07
68	SERA_BOVIN (Q5EAD2) D-3-phosphoglycerate dehydrogenase (EC 1.1.1...	56	1e-07
69	FDH_PICAN (P33677) Formate dehydrogenase (EC 1.2.1.2) (NAD-depen...	56	1e-07
70	YGT5_YEAST (P53100) Putative 2-hydroxyacid dehydrogenase YGL185C...	54	4e-07
71	YN14_YEAST (P53839) Putative 2-hydroxyacid dehydrogenase YNL274C...	54	4e-07
72	SERA_YEAST (P40054) D-3-phosphoglycerate dehydrogenase 1 (EC 1.1...	53	1e-06
73	SER33_YEAST (P40510) D-3-phosphoglycerate dehydrogenase 2 (EC 1....	53	1e-06
74	YP113_YEAST (Q02961) Putative 2-hydroxyacid dehydrogenase YPL113...	52	1e-06
75	LDHD_LEUMC (P51011) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH...	52	1e-06
76	FDH_EMENI (Q03134) Probable formate dehydrogenase (EC 1.2.1.2) (...	52	2e-06
77	LDHD_STAES (Q8CN22) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH...	52	2e-06
78	LDHD_STAEQ (Q5HLA0) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH...	52	2e-06
79	DHGY_HYPME (P36234) Glycerate dehydrogenase (EC 1.1.1.29) (NADH-...	51	4e-06
80	SERA_PONPY (Q5R7M2) D-3-phosphoglycerate dehydrogenase (EC 1.1.1...	51	4e-06
81	DDH_HAEIN (P44501) 2-hydroxyacid dehydrogenase homolog (EC 1.1.1.-)	51	4e-06
82	PDXB_YERPS (Q668W7) Erythronate-4-phosphate dehydrogenase (EC 1....	50	6e-06
83	PDXB_YERPE (Q8D0U3) Erythronate-4-phosphate dehydrogenase (EC 1....	50	6e-06
84	LDHD_LACPL (Q88VJ2) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH)	50	6e-06
85	YEAA_SCHPO (O14075) Putative 2-hydroxyacid dehydrogenase UNK4.10...	50	8e-06
86	LDHD_STAAR (Q6GDS2) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH...	50	8e-06
87	YMP5_STRCO (P43169) Hypothetical protein in mprR 3'region (EC 1....	49	1e-05
88	LDHD_STAAW (Q8NUT2) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH...	49	2e-05
89	LDHD_STAAU (P72357) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH...	49	2e-05
90	LDHD_STAAS (Q6G6F1) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH...	49	2e-05
91	LDHD_STAAN (P99116) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH...	49	2e-05
92	LDHD_STAAM (P63940) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH...	49	2e-05
93	LDHD_STAAC (Q5HD29) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH...	49	2e-05
94	PDXB_PSEAE (Q9I3W9) Erythronate-4-phosphate dehydrogenase (EC 1....	48	3e-05
95	PDXB_ECO57 (Q8XCR0) Erythronate-4-phosphate dehydrogenase (EC 1....	47	4e-05
96	LDHD_LACPE (P26298) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH...	47	5e-05
97	PDXB_PHOLL (Q7N2B2) Erythronate-4-phosphate dehydrogenase (EC 1....	47	7e-05
98	LDHD_ECOLI (P52643) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH...	47	7e-05
99	PDXB_SHIFL (Q83QR1) Erythronate-4-phosphate dehydrogenase (EC 1....	46	9e-05
100	PDXB_ECOL6 (Q8FFH2) Erythronate-4-phosphate dehydrogenase (EC 1....	46	1e-04
101	PDXB_ECOLI (P05459) Erythronate-4-phosphate dehydrogenase (EC 1....	43	0.001
102	PDXB_WIGBR (Q8D2P6) Erythronate-4-phosphate dehydrogenase (EC 1....	42	0.001
103	PDXB_SHEON (Q8ECR2) Erythronate-4-phosphate dehydrogenase (EC 1....	42	0.002
104	PDXB_BACTN (Q8A2E4) Erythronate-4-phosphate dehydrogenase (EC 1....	42	0.002
105	PDXB_COXBU (Q83AR8) Erythronate-4-phosphate dehydrogenase (EC 1....	41	0.004
106	PDXB_VIBVY (Q7MIT6) Erythronate-4-phosphate dehydrogenase (EC 1....	40	0.005
107	PDXB_VIBVU (Q8DB36) Erythronate-4-phosphate dehydrogenase (EC 1....	40	0.007
108	PDXB_SALTY (P60802) Erythronate-4-phosphate dehydrogenase (EC 1....	39	0.015
109	PDXB_SALTI (P60801) Erythronate-4-phosphate dehydrogenase (EC 1....	39	0.015
110	PDXB_VIBCH (Q9KQ92) Erythronate-4-phosphate dehydrogenase (EC 1....	38	0.025
111	PDXB_VIBPA (Q87MN8) Erythronate-4-phosphate dehydrogenase (EC 1....	37	0.074
112	PDXB_ERWCT (Q6D2N5) Erythronate-4-phosphate dehydrogenase (EC 1....	36	0.13
113	PDXB_BLOFL (Q7VRU9) Erythronate-4-phosphate dehydrogenase (EC 1....	34	0.37
114	PDXB_PHOPR (Q6LNU2) Erythronate-4-phosphate dehydrogenase (EC 1....	33	0.63
115	PDXB_SHESP (Q56731) Erythronate-4-phosphate dehydrogenase (EC 1....	33	0.63
116	EEP_ENTFA (Q9RPP2) Probable protease eep (EC 3.4.24.-)	32	2.4
117	SMCE1_MOUSE (O54941) SWI/SNF-related matrix-associated actin-dep...	31	3.1
118	SMCE1_HUMAN (Q969G3) SWI/SNF-related matrix-associated actin-dep...	31	3.1
119	PDXB_PSESM (Q884R9) Erythronate-4-phosphate dehydrogenase (EC 1....	31	3.1
120	DHAR_CITFR (P45512) Glycerol metabolism operon regulatory protein	31	4.1
121	SWR1_YARLI (Q6CA87) Helicase SWR1 (EC 3.6.1.-)	30	5.3
122	GUNC_FUSOX (P46237) Endoglucanase type C precursor (EC 3.2.1.4) ...	30	5.3
123	LYS1_EMENI (Q870G1) Saccharopine dehydrogenase [NAD+, L-lysine-f...	30	5.3
124	Y2031_STRP8 (Q8NZB3) Hypothetical zinc metalloprotease spyM18_20...	30	9.1
125	Y1963_STRP1 (Q99XY3) Hypothetical zinc metalloprotease SPy1963/M...	30	9.1
126	Y1689_STRP3 (Q8K5S6) Hypothetical zinc metalloprotease SpyM3_168...	30	9.1
127	Y1682_STRP6 (Q5X9U6) Hypothetical zinc metalloprotease M6_Spy168...	30	9.1

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>GYAR_PYRAB (Q9UYR1) Glyoxylate reductase (EC 1.1.1.26) (Glycolate reductase)|
          Length = 335

 Score = 95.1 bits (235), Expect = 2e-19
 Identities = 57/166 (34%), Positives = 94/166 (56%)
 Frame = -1

Query: 694 FGAIGMEIAKRLRPFGVKILATKRNWSSNTASCDLDGLVDKKGGPEEMYELAREADIVIT 515
           FG IG  IAKR R F ++IL     + S T   +++  ++ +  P +  EL RE+D V+ 
Sbjct: 159 FGRIGQAIAKRARGFDMRIL-----YYSRTRKPEVEKELNAEFKPLD--ELLRESDFVVL 211

Query: 514 CMTLNNESVGIVNHKFLSTLKKGSYLINIARGRLLDYTAVFNHLESGHLGGLGIDVAWTE 335
            + LN E+  ++N + L  +K+ + LIN+ARG+++D  A+   L+ G + G G+DV   E
Sbjct: 212 AVPLNKETYHMINEERLKMMKRTAILINVARGKVIDTKALIKALKEGWIAGAGLDVYEEE 271

Query: 334 PFDPEDPILKFPNVIITPHIAGITEYSYRTMAKVVGDVALKLHAGE 197
           P+  E+ +    NV++TPHI   T  +   MAK+V +  +    GE
Sbjct: 272 PYYNEE-LFSLDNVVLTPHIGSATFGAREGMAKLVAENLIAFKRGE 316

---

>GYAR_PYRHO (O58320) Glyoxylate reductase (EC 1.1.1.26) (Glycolate reductase)|
          Length = 334

 Score = 88.6 bits (218), Expect = 2e-17
 Identities = 55/165 (33%), Positives = 92/165 (55%)
 Frame = -1

Query: 691 GAIGMEIAKRLRPFGVKILATKRNWSSNTASCDLDGLVDKKGGPEEMYELAREADIVITC 512
           G IG  IAKR + F ++IL     + S T   +++  ++ +  P E  +L RE+D V+  
Sbjct: 159 GRIGQAIAKRAKGFNMRIL-----YYSRTRKEEVERELNAEFKPLE--DLLRESDFVVLA 211

Query: 511 MTLNNESVGIVNHKFLSTLKKGSYLINIARGRLLDYTAVFNHLESGHLGGLGIDVAWTEP 332
           + L  E+  ++N + L  +KK + LINIARG+++D  A+   L+ G + G G+DV   EP
Sbjct: 212 VPLTRETYHLINEERLKLMKKTAILINIARGKVVDTNALVKALKEGWIAGAGLDVFEEEP 271

Query: 331 FDPEDPILKFPNVIITPHIAGITEYSYRTMAKVVGDVALKLHAGE 197
           +  E+ + K  NV++TPHI   +  +   MA++V    +    GE
Sbjct: 272 YYNEE-LFKLDNVVLTPHIGSASFGAREGMAELVAKNLIAFKRGE 315

---

>GYAR_PYRKO (Q5JEZ2) Glyoxylate reductase (EC 1.1.1.26) (Glycolate reductase)|
          Length = 333

 Score = 87.4 bits (215), Expect = 4e-17
 Identities = 54/168 (32%), Positives = 89/168 (52%), Gaps = 2/168 (1%)
 Frame = -1

Query: 694 FGAIGMEIAKRLRPFGVKILATKRNWSSNTASCDLDGLVDKKGGPE--EMYELAREADIV 521
           FG IG  +A+R R FG++IL   R+              +K+ G E   + +L RE+D V
Sbjct: 158 FGRIGQAVARRARGFGMRILYYSRSRKPEA---------EKELGAEFRSLEDLLRESDFV 208

Query: 520 ITCMTLNNESVGIVNHKFLSTLKKGSYLINIARGRLLDYTAVFNHLESGHLGGLGIDVAW 341
           +  + L  E+  ++N + L  +KK + L+NIARG+++D  A+   L+ G + G G+DV  
Sbjct: 209 VLAVPLTKETQYMINEERLRLMKKTAILVNIARGKVVDTKALMKALKEGWIAGAGLDVYE 268

Query: 340 TEPFDPEDPILKFPNVIITPHIAGITEYSYRTMAKVVGDVALKLHAGE 197
            EP+  E+ +    NV++ PHI   T  +   MA++V    +    GE
Sbjct: 269 EEPYYNEE-LFSLKNVVLAPHIGSATYGAREGMAELVARNLIAFKNGE 315

---

>GYAR_PYRFU (Q8U3Y2) Glyoxylate reductase (EC 1.1.1.26) (Glycolate reductase)|
          Length = 336

 Score = 87.0 bits (214), Expect = 5e-17
 Identities = 54/168 (32%), Positives = 89/168 (52%), Gaps = 2/168 (1%)
 Frame = -1

Query: 694 FGAIGMEIAKRLRPFGVKILATKRNWSSNTASCDLDGLVDKKGGPE--EMYELAREADIV 521
           FG IG  IA+R + F ++IL   R   S           +K+ G E   + E+ +E+D V
Sbjct: 158 FGRIGQAIARRAKGFNMRILYYSRTRKSQA---------EKELGAEYRPLEEVLKESDFV 208

Query: 520 ITCMTLNNESVGIVNHKFLSTLKKGSYLINIARGRLLDYTAVFNHLESGHLGGLGIDVAW 341
           I  + L  E++ ++N + L  +K  + L+NIARG+++D  A+   L+ G + G G+DV  
Sbjct: 209 ILAVPLTKETMYMINEERLKLMKPTAILVNIARGKVVDTKALIKALKEGWIAGAGLDVFE 268

Query: 340 TEPFDPEDPILKFPNVIITPHIAGITEYSYRTMAKVVGDVALKLHAGE 197
            EP+  E+ +    NV++TPHI   T  +   MA++V    +    GE
Sbjct: 269 EEPYYNEE-LFSLDNVVLTPHIGSATFEAREAMAELVARNLIAFKRGE 315

---

>Y1556_HAEIN (P45250) Putative 2-hydroxyacid dehydrogenase HI1556 (EC 1.-.-.-)|
          Length = 315

 Score = 83.6 bits (205), Expect = 5e-16
 Identities = 50/154 (32%), Positives = 84/154 (54%), Gaps = 4/154 (2%)
 Frame = -1

Query: 691 GAIGMEIAKRLRPFGVKILATKRNWSSNTASCDLDGLVDKKGGPEEMYELAREADIVITC 512
           G +G E+ +     G+K+L  +            D  V ++G      E+ ++ADIV   
Sbjct: 155 GCLGTEVGRLANAVGMKVLYAEHK----------DATVCREGYTP-FDEVLKQADIVTLH 203

Query: 511 MTLNNESVGIVNHKFLSTLKKGSYLINIARGRLLDYTAVFNHLESGHLGGLGIDVAWTEP 332
             L   +  ++N + LS +KKG++LIN  RG L+D  A+ + L++GHLGG  +DV   EP
Sbjct: 204 CPLTETTKDLINAETLSKMKKGAFLINTGRGPLIDELALVDALKTGHLGGAALDVMVKEP 263

Query: 331 FDPEDPIL----KFPNVIITPHIAGITEYSYRTM 242
            + ++P++      PN+IITPHIA  ++ +  T+
Sbjct: 264 PEKDNPLILAAKTMPNLIITPHIAWASDSAVTTL 297

---

>GRHPR_MOUSE (Q91Z53) Glyoxylate reductase/hydroxypyruvate reductase (EC|
           1.1.1.79)
          Length = 328

 Score = 81.6 bits (200), Expect = 2e-15
 Identities = 50/166 (30%), Positives = 83/166 (50%), Gaps = 1/166 (0%)
 Frame = -1

Query: 691 GAIGMEIAKRLRPFGV-KILATKRNWSSNTASCDLDGLVDKKGGPEEMYELAREADIVIT 515
           G IG  IA+RL+PFGV + L T R      A+       + +     + +LA E+D ++ 
Sbjct: 162 GRIGQAIARRLKPFGVQRFLYTGRQPRPQEAA-------EFQAEFVPIAQLAAESDFIVV 214

Query: 514 CMTLNNESVGIVNHKFLSTLKKGSYLINIARGRLLDYTAVFNHLESGHLGGLGIDVAWTE 335
             +L  +++G+ +  F   +K  +  INI+RG +++   ++  L SG +   G+DV   E
Sbjct: 215 SCSLTPDTMGLCSKDFFQKMKNTAIFINISRGDVVNQEDLYQALASGQIAAAGLDVTTPE 274

Query: 334 PFDPEDPILKFPNVIITPHIAGITEYSYRTMAKVVGDVALKLHAGE 197
           P  P  P+L   N +I PHI   T  +  TM+ +  +  L    GE
Sbjct: 275 PLPPSHPLLTLKNCVILPHIGSATYKTRNTMSLLAANNLLAGLRGE 320

---

>FDH_ARATH (Q9S7E4) Formate dehydrogenase, mitochondrial precursor (EC|
           1.2.1.2) (NAD-dependent formate dehydrogenase) (FDH)
          Length = 384

 Score = 81.6 bits (200), Expect = 2e-15
 Identities = 51/170 (30%), Positives = 86/170 (50%), Gaps = 3/170 (1%)
 Frame = -1

Query: 691 GAIGMEIAKRLRPFGVKILATKRNWSSNTASCDLDGLVDKKGGP---EEMYELAREADIV 521
           G IG  + +RL+PFG  +L   R          +   ++K+ G    E++ E+  + D++
Sbjct: 206 GRIGKLLLQRLKPFGCNLLYHDR--------LQMAPELEKETGAKFVEDLNEMLPKCDVI 257

Query: 520 ITCMTLNNESVGIVNHKFLSTLKKGSYLINIARGRLLDYTAVFNHLESGHLGGLGIDVAW 341
           +  M L  ++ G+ N + +  LKKG  ++N ARG +++  AV + +ESGH+GG   DV  
Sbjct: 258 VINMPLTEKTRGMFNKELIGKLKKGVLIVNNARGAIMERQAVVDAVESGHIGGYSGDVWD 317

Query: 340 TEPFDPEDPILKFPNVIITPHIAGITEYSYRTMAKVVGDVALKLHAGEPF 191
            +P   + P    PN  +TPH +G T  +    A    D+  +   GE F
Sbjct: 318 PQPAPKDHPWRYMPNQAMTPHTSGTTIDAQLRYAAGTKDMLERYFKGEDF 367

---

>GRHPR_HUMAN (Q9UBQ7) Glyoxylate reductase/hydroxypyruvate reductase (EC|
           1.1.1.79)
          Length = 328

 Score = 81.3 bits (199), Expect = 3e-15
 Identities = 52/167 (31%), Positives = 80/167 (47%), Gaps = 1/167 (0%)
 Frame = -1

Query: 691 GAIGMEIAKRLRPFGV-KILATKRNWSSNTASCDLDGLVDKKGGPEEMYELAREADIVIT 515
           G IG  IA+RL+PFGV + L T R      A+      V          ELA ++D ++ 
Sbjct: 162 GRIGQAIARRLKPFGVQRFLYTGRQPRPEEAAEFQAEFVSTP-------ELAAQSDFIVV 214

Query: 514 CMTLNNESVGIVNHKFLSTLKKGSYLINIARGRLLDYTAVFNHLESGHLGGLGIDVAWTE 335
             +L   + G+ N  F   +K+ +  INI+RG +++   ++  L SG +   G+DV   E
Sbjct: 215 ACSLTPATEGLCNKDFFQKMKETAVFINISRGDVVNQDDLYQALASGKIAAAGLDVTSPE 274

Query: 334 PFDPEDPILKFPNVIITPHIAGITEYSYRTMAKVVGDVALKLHAGEP 194
           P     P+L   N +I PHI   T  +  TM+ +  +  L    GEP
Sbjct: 275 PLPTNHPLLTLKNCVILPHIGSATHRTRNTMSLLAANNLLAGLRGEP 321

---

>DHGY_METEX (Q59516) Glycerate dehydrogenase (EC 1.1.1.29) (NADH-dependent|
           hydroxypyruvate reductase) (HPR) (GDH) (Hydroxypyruvate
           dehydrogenase) (Glyoxylate reductase) (HPR-A)
          Length = 313

 Score = 80.5 bits (197), Expect = 4e-15
 Identities = 54/176 (30%), Positives = 90/176 (51%), Gaps = 4/176 (2%)
 Frame = -1

Query: 694 FGAIGMEIAKRLRPFGVKILATKRNWSSNTASCDLDGLVDKKGGPEEMYELAREADIVIT 515
           +GA+G  IAKR    G+K+LA              DGLVD       +  +  ++D++  
Sbjct: 154 YGALGKSIAKRAEALGMKVLAFD--------VFPQDGLVD-------LETILTQSDVITL 198

Query: 514 CMTLNNESVGIVNHKFLSTLKKGSYLINIARGRLLDYTAVFNHLESGHLGGLGIDVAWTE 335
            + L  ++  ++  + L  +K+ + LIN ARG L+D  A+   L+ G +GG G DV   E
Sbjct: 199 HVPLTPDTKNMIGAEQLKKMKRSAILINTARGGLVDEAALLQALKDGTIGGAGFDVVAQE 258

Query: 334 PFDPEDPIL----KFPNVIITPHIAGITEYSYRTMAKVVGDVALKLHAGEPFNEIE 179
           P  P+D  +      PN+I+TPH+A  ++ + + +A  + D      AG+P N +E
Sbjct: 259 P--PKDGNILCDADLPNLIVTPHVAWASKEAMQILADQLVDNVEAFVAGKPQNVVE 312

---

>VANH_ENTFC (Q05709) D-specific alpha-keto acid dehydrogenase (EC 1.1.1.-)|
           (Vancomycin resistance protein vanH)
          Length = 322

 Score = 79.7 bits (195), Expect = 8e-15
 Identities = 57/168 (33%), Positives = 84/168 (50%), Gaps = 14/168 (8%)
 Frame = -1

Query: 691 GAIGMEIAKRLRPFGVKILATKRNWSSNTASCDLDGLVDKKGGPEEMYELAREADIVITC 512
           G IG  + +RLR FG K+LA  R+ S        D             EL + +DIV   
Sbjct: 155 GQIGKAVIERLRGFGCKVLAYSRSRSIEVNYVPFD-------------ELLQNSDIVTLH 201

Query: 511 MTLNNESVGIVNHKFLSTLKKGSYLINIARGRLLDYTAVFNHLESGHLGGLGIDVAWTE- 335
           + LN ++  I++H+ +  +K+G++LIN  RG L+D   +   LE+G LGG  +DV   E 
Sbjct: 202 VPLNTDTHYIISHEQIQRMKQGAFLINTGRGPLVDTYELVKALENGKLGGAALDVLEGEE 261

Query: 334 ----------PFDPED--PILKFPNVIITPHIAGITEYSYR-TMAKVV 230
                     P D +    + + PNVIITPH A  TE + R T+ K +
Sbjct: 262 EFFYSDCTQKPIDNQFLLKLQRMPNVIITPHTAYYTEQALRDTVEKTI 309

---

>YCDW_ECOLI (P75913) Putative 2-hydroxyacid dehydrogenase ycdW (EC 1.-.-.-)|
          Length = 325

 Score = 79.0 bits (193), Expect = 1e-14
 Identities = 50/162 (30%), Positives = 82/162 (50%), Gaps = 9/162 (5%)
 Frame = -1

Query: 691 GAIGMEIAKRLRPFGVKILA---TKRNWSSNTASCDLDGLVDKKGGPEEMYELAREADIV 521
           G +G ++A+ L+ +   +     T+++W            V    G EE+     +  ++
Sbjct: 158 GVLGSKVAQSLQTWRFPLRCWSRTRKSWPG----------VQSFAGREELSAFLSQCRVL 207

Query: 520 ITCMTLNNESVGIVNHKFLSTLKKGSYLINIARGRLLDYTAVFNHLESGHLGGLGIDVAW 341
           I  +    E+VGI+N + L  L  G+YL+N+ARG  +    +   L+SG + G  +DV  
Sbjct: 208 INLLPNTPETVGIINQQLLEKLPDGAYLLNLARGVHVVEDDLLAALDSGKVKGAMLDVFN 267

Query: 340 TEPFDPEDPILKFPNVIITPHIAGIT------EYSYRTMAKV 233
            EP  PE P+ + P V ITPH+A IT      EY  RT+A++
Sbjct: 268 REPLPPESPLWQHPRVTITPHVAAITRPAEAVEYISRTIAQL 309

---

>GYAR_THELI (Q9C4M5) Glyoxylate reductase (EC 1.1.1.26) (Glycolate reductase)|
          Length = 331

 Score = 78.6 bits (192), Expect = 2e-14
 Identities = 50/168 (29%), Positives = 83/168 (49%), Gaps = 2/168 (1%)
 Frame = -1

Query: 694 FGAIGMEIAKRLRPFGVKILATKRNWSSNTASCDLDGLVDKKGGPE--EMYELAREADIV 521
           FG IG  +AKR + FG+KI+   R               +++ G E  +   L +E+D +
Sbjct: 158 FGRIGQALAKRAKGFGMKIIYYSRTRKPEA---------EEEIGAEYVDFETLLKESDFI 208

Query: 520 ITCMTLNNESVGIVNHKFLSTLKKGSYLINIARGRLLDYTAVFNHLESGHLGGLGIDVAW 341
              + L  E+  ++  K L  +K  + LIN +RG ++D  A+   L+ G + G G+DV  
Sbjct: 209 SLHVPLTKETYHMIGEKELKLMKPNAILINTSRGAVVDTNALIKALKEGWIAGAGLDVFE 268

Query: 340 TEPFDPEDPILKFPNVIITPHIAGITEYSYRTMAKVVGDVALKLHAGE 197
            EP+  E+ + K  NV++ PHI   T  +   MA++V    +    GE
Sbjct: 269 EEPYYNEE-LFKLKNVVLAPHIGSATHEAREGMAELVAKNLIAFAKGE 315

---

>SERA_ARCFU (O29445) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (PGDH)|
          Length = 527

 Score = 77.0 bits (188), Expect = 5e-14
 Identities = 44/166 (26%), Positives = 80/166 (48%)
 Frame = -1

Query: 691 GAIGMEIAKRLRPFGVKILATKRNWSSNTASCDLDGLVDKKGGPEEMYELAREADIVITC 512
           G +G E+AKR +   + +LA     S   A      LVD          L   +D++   
Sbjct: 148 GRVGFEVAKRCKALEMNVLAYDPFVSKERAEQIGVKLVD-------FDTLLASSDVITVH 200

Query: 511 MTLNNESVGIVNHKFLSTLKKGSYLINIARGRLLDYTAVFNHLESGHLGGLGIDVAWTEP 332
           +    E++G++       +K G  ++N ARG ++D  A++  +++G +    +DV   EP
Sbjct: 201 VPRTKETIGLIGKGQFEKMKDGVIVVNAARGGIVDEAALYEAIKAGKVAAAALDVYEKEP 260

Query: 331 FDPEDPILKFPNVIITPHIAGITEYSYRTMAKVVGDVALKLHAGEP 194
             P++P+LK  NV+ TPHIA  T  +   +  ++ +  + +  G P
Sbjct: 261 PSPDNPLLKLDNVVTTPHIAASTREAQLNVGMIIAEDIVNMAKGLP 306

---

>FDH_PSESR (P33160) Formate dehydrogenase (EC 1.2.1.2) (NAD-dependent formate|
           dehydrogenase) (FDH)
          Length = 400

 Score = 76.3 bits (186), Expect = 8e-14
 Identities = 51/169 (30%), Positives = 82/169 (48%)
 Frame = -1

Query: 691 GAIGMEIAKRLRPFGVKILATKRNWSSNTASCDLDGLVDKKGGPEEMYELAREADIVITC 512
           G IG+ + +RL PF V +  T R+    +   +L+  +      E+MY +    D+V   
Sbjct: 200 GRIGLAVLRRLAPFDVHLHYTDRHRLPESVEKELN--LTWHATREDMYPVC---DVVTLN 254

Query: 511 MTLNNESVGIVNHKFLSTLKKGSYLINIARGRLLDYTAVFNHLESGHLGGLGIDVAWTEP 332
             L+ E+  ++N + L   K+G+Y++N ARG+L D  AV   LESG L G   DV + +P
Sbjct: 255 CPLHPETEHMINDETLKLFKRGAYIVNTARGKLCDRDAVARALESGRLAGYAGDVWFPQP 314

Query: 331 FDPEDPILKFPNVIITPHIAGITEYSYRTMAKVVGDVALKLHAGEPFNE 185
              + P    P   +TPHI+G T  +    A    ++      G P  +
Sbjct: 315 APKDHPWRTMPYNGMTPHISGTTLTAQARYAAGTREILECFFEGRPIRD 363

---

>FDH2_ORYSA (Q67U69) Formate dehydrogenase 2, mitochondrial precursor (EC|
           1.2.1.2) (NAD-dependent formate dehydrogenase 2) (FDH 2)
          Length = 378

 Score = 76.3 bits (186), Expect = 8e-14
 Identities = 50/170 (29%), Positives = 85/170 (50%), Gaps = 3/170 (1%)
 Frame = -1

Query: 691 GAIGMEIAKRLRPFGVKILATKRNWSSNTASCDLDGLVDKKGGP---EEMYELAREADIV 521
           G IG  + +RL+PF   ++   R          +D  ++K+ G    E++  +  + D+V
Sbjct: 200 GRIGRLLLQRLKPFNCNLMYHDR--------VKIDPELEKEIGAKYEEDLDAMLPKCDVV 251

Query: 520 ITCMTLNNESVGIVNHKFLSTLKKGSYLINIARGRLLDYTAVFNHLESGHLGGLGIDVAW 341
           +  M L  ++ G+ N + ++ +KKG  ++N ARG ++D  AV +   SGH+ G G DV +
Sbjct: 252 VINMPLTEKTRGMFNKERIAKMKKGVTIVNNARGAIMDTQAVADACASGHVAGYGGDVWF 311

Query: 340 TEPFDPEDPILKFPNVIITPHIAGITEYSYRTMAKVVGDVALKLHAGEPF 191
            +P   + P    PN  +TPH +G T       A  V D+  +   GE F
Sbjct: 312 PQPAPKDHPWRYMPNHAMTPHCSGTTIDGQLRYAAGVKDMLDRYFKGEDF 361

---

>SERA_BACSU (P35136) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (PGDH)|
          Length = 525

 Score = 75.5 bits (184), Expect = 1e-13
 Identities = 53/168 (31%), Positives = 81/168 (48%), Gaps = 2/168 (1%)
 Frame = -1

Query: 691 GAIGMEIAKRLRPFGVKILATKRNWSSNTASCDLDGLVDKKGGPEE--MYELAREADIVI 518
           G IG EIA+R   FG+ +       +   A         KK G       E+   ADI+ 
Sbjct: 147 GRIGSEIAQRRGAFGMTVHVFDPFLTEERA---------KKIGVNSRTFEEVLESADIIT 197

Query: 517 TCMTLNNESVGIVNHKFLSTLKKGSYLINIARGRLLDYTAVFNHLESGHLGGLGIDVAWT 338
               L  E+ G++N + ++  KKG  LIN ARG ++D  A+   LE+GH+ G  +DV   
Sbjct: 198 VHTPLTKETKGLLNKETIAKTKKGVRLINCARGGIIDEAALLEALENGHVAGAALDVFEV 257

Query: 337 EPFDPEDPILKFPNVIITPHIAGITEYSYRTMAKVVGDVALKLHAGEP 194
           EP   ++ ++  P VI TPH+   T+ +   +A  V +  L+   G P
Sbjct: 258 EP-PVDNKLVDHPLVIATPHLGASTKEAQLNVAAQVSEEVLQFAKGLP 304

---

>FDH_SOLTU (Q07511) Formate dehydrogenase, mitochondrial precursor (EC|
           1.2.1.2) (NAD-dependent formate dehydrogenase) (FDH)
          Length = 381

 Score = 75.1 bits (183), Expect = 2e-13
 Identities = 49/167 (29%), Positives = 84/167 (50%)
 Frame = -1

Query: 691 GAIGMEIAKRLRPFGVKILATKRNWSSNTASCDLDGLVDKKGGPEEMYELAREADIVITC 512
           G IG  + +RL+PF   +L   R    +    +L+  +  K   E++ ++  + DIV+  
Sbjct: 203 GRIGRLLLQRLKPFNCNLLYHDRLKMDS----ELENQIGAKF-EEDLDKMLSKCDIVVIN 257

Query: 511 MTLNNESVGIVNHKFLSTLKKGSYLINIARGRLLDYTAVFNHLESGHLGGLGIDVAWTEP 332
             L  ++ G+ + + ++ LKKG  ++N ARG ++D  AV +   SGH+ G   DV + +P
Sbjct: 258 TPLTEKTKGMFDKERIAKLKKGVLIVNNARGAIMDTQAVVDACNSGHIAGYSGDVWYPQP 317

Query: 331 FDPEDPILKFPNVIITPHIAGITEYSYRTMAKVVGDVALKLHAGEPF 191
              + P    PN  +TPHI+G T  +    A    D+  +   GE F
Sbjct: 318 APKDHPWRYMPNQAMTPHISGTTIDAQLRYAAGTKDMLDRYFKGEDF 364

---

>FDH_HORVU (Q9ZRI8) Formate dehydrogenase, mitochondrial precursor (EC|
           1.2.1.2) (NAD-dependent formate dehydrogenase) (FDH)
          Length = 377

 Score = 74.7 bits (182), Expect = 2e-13
 Identities = 49/170 (28%), Positives = 85/170 (50%), Gaps = 3/170 (1%)
 Frame = -1

Query: 691 GAIGMEIAKRLRPFGVKILATKRNWSSNTASCDLDGLVDKKGGP---EEMYELAREADIV 521
           G  G  + +RL+PF   +L   R          ++  ++K+ G    E++  +  + D+V
Sbjct: 199 GRYGRLLLQRLKPFNCNLLYHDR--------LQINPELEKEIGAKFEEDLDAMLPKCDVV 250

Query: 520 ITCMTLNNESVGIVNHKFLSTLKKGSYLINIARGRLLDYTAVFNHLESGHLGGLGIDVAW 341
           +    L  ++ G+ N + ++ +KKG  ++N ARG ++D  AV +   SGH+ G G DV +
Sbjct: 251 VINTPLTEKTRGMFNKEKIAKMKKGVIIVNNARGAIMDTQAVADACSSGHIAGYGGDVWF 310

Query: 340 TEPFDPEDPILKFPNVIITPHIAGITEYSYRTMAKVVGDVALKLHAGEPF 191
            +P   + P    PN  +TPHI+G T  +    A  V D+  +   GE F
Sbjct: 311 PQPAPKDHPWRYMPNHAMTPHISGTTIDAQLRYAAGVKDMLDRYFKGEEF 360

---

>YPRB2_CORML (P0C1E9) Hypothetical protein in proB 3'region (EC 1.-.-.-)|
          Length = 304

 Score = 74.7 bits (182), Expect = 2e-13
 Identities = 42/144 (29%), Positives = 74/144 (51%)
 Frame = -1

Query: 691 GAIGMEIAKRLRPFGVKILATKRNWSSNTASCDLDGLVDKKGGPEEMYELAREADIVITC 512
           G IG+ + + L+PF VK +A       N +   ++G  D+    ++   +  EAD+ +  
Sbjct: 135 GGIGVRLLEMLKPFNVKTIAV------NNSGRPVEG-ADETFAMDKAEHVWAEADVFVLI 187

Query: 511 MTLNNESVGIVNHKFLSTLKKGSYLINIARGRLLDYTAVFNHLESGHLGGLGIDVAWTEP 332
           + L + +  IVN + L  +K  + L+N+ RG L++   + + L +G + G  +DV   EP
Sbjct: 188 LPLTDATYQIVNAETLGKMKPSAVLVNVGRGPLINTDDLVDALNNGTIAGAALDVTDPEP 247

Query: 331 FDPEDPILKFPNVIITPHIAGITE 260
                P+ +  NV+ITPH A   E
Sbjct: 248 LPDSHPLWEMDNVVITPHTANTNE 271

---

>FDH1_ORYSA (Q9SXP2) Formate dehydrogenase 1, mitochondrial precursor (EC|
           1.2.1.2) (NAD-dependent formate dehydrogenase 1) (FDH 1)
          Length = 376

 Score = 74.3 bits (181), Expect = 3e-13
 Identities = 49/170 (28%), Positives = 85/170 (50%), Gaps = 3/170 (1%)
 Frame = -1

Query: 691 GAIGMEIAKRLRPFGVKILATKRNWSSNTASCDLDGLVDKKGGP---EEMYELAREADIV 521
           G IG  + +RL+PF   +L   R          +D  ++K+ G    E++  +  + D++
Sbjct: 198 GRIGRLLLQRLKPFNCNLLYHDR--------LKIDPELEKEIGAKYEEDLDAMLPKCDVI 249

Query: 520 ITCMTLNNESVGIVNHKFLSTLKKGSYLINIARGRLLDYTAVFNHLESGHLGGLGIDVAW 341
           +    L  ++ G+ N + ++ +KKG  ++N ARG ++D  AV +   SG + G G DV +
Sbjct: 250 VINTPLTEKTRGMFNKERIAKMKKGVIIVNNARGAIMDTQAVADACSSGQVAGYGGDVWF 309

Query: 340 TEPFDPEDPILKFPNVIITPHIAGITEYSYRTMAKVVGDVALKLHAGEPF 191
            +P   + P    PN  +TPHI+G T  +    A  V D+  +   GE F
Sbjct: 310 PQPAPKDHPWRYMPNHAMTPHISGTTIDAQLRYAAGVKDMLDRYFKGEDF 359

---

>GYAR_AERPE (Q9YAW4) Glyoxylate reductase (EC 1.1.1.26) (Glycolate reductase)|
          Length = 335

 Score = 73.6 bits (179), Expect = 5e-13
 Identities = 44/158 (27%), Positives = 78/158 (49%), Gaps = 2/158 (1%)
 Frame = -1

Query: 691 GAIGMEIAKRLRPFGVKILATKRNWSSNTASCDLDGLVDKKGGPE--EMYELAREADIVI 518
           G IG  +A+  + FG++I+   R+             ++K+ G E   + +L RE+DI+ 
Sbjct: 160 GRIGSRVAEIGKAFGMRIIYHSRSRKRE---------IEKELGAEYRSLEDLLRESDILS 210

Query: 517 TCMTLNNESVGIVNHKFLSTLKKGSYLINIARGRLLDYTAVFNHLESGHLGGLGIDVAWT 338
             + L +E+  ++    L  +KK + L+N  RG ++D  A+   L  G +    +DV   
Sbjct: 211 IHLPLTDETRHLIGESELKLMKKTAILVNTGRGAIVDTGALVKALREGWIAAAALDVFEE 270

Query: 337 EPFDPEDPILKFPNVIITPHIAGITEYSYRTMAKVVGD 224
           EP +P  P+  F NV++ PH A  T  +   MA +  +
Sbjct: 271 EPLNPNHPLTAFKNVVLAPHAASATRETRLRMAMMAAE 308

---

>Y2355_CORGL (P0C1E8) Hypothetical protein Cgl2355/cg2587 (EC 1.-.-.-)|
          Length = 304

 Score = 73.6 bits (179), Expect = 5e-13
 Identities = 41/144 (28%), Positives = 74/144 (51%)
 Frame = -1

Query: 691 GAIGMEIAKRLRPFGVKILATKRNWSSNTASCDLDGLVDKKGGPEEMYELAREADIVITC 512
           G IG+ + + L+PF VK +A       N +   ++G  D+    ++   +  EAD+ +  
Sbjct: 135 GGIGVRLLEMLKPFNVKTIAV------NNSGRPVEG-ADETFAMDKAEHVWAEADVFVLI 187

Query: 511 MTLNNESVGIVNHKFLSTLKKGSYLINIARGRLLDYTAVFNHLESGHLGGLGIDVAWTEP 332
           + L + +  IVN + L  +K  + ++N+ RG L++   + + L +G + G  +DV   EP
Sbjct: 188 LPLTDATYQIVNAETLGKMKPSAVVVNVGRGPLINTDDLVDALNNGTIAGAALDVTDPEP 247

Query: 331 FDPEDPILKFPNVIITPHIAGITE 260
                P+ +  NV+ITPH A   E
Sbjct: 248 LPDSHPLWEMDNVVITPHTANTNE 271

---

>SERA_METJA (Q58424) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (PGDH)|
          Length = 524

 Score = 73.6 bits (179), Expect = 5e-13
 Identities = 47/165 (28%), Positives = 81/165 (49%)
 Frame = -1

Query: 691 GAIGMEIAKRLRPFGVKILATKRNWSSNTASCDLDGLVDKKGGPEEMYELAREADIVITC 512
           G IG ++ KR + FG+ I+          A      LVD      ++ EL + AD +   
Sbjct: 148 GRIGQQVVKRAKAFGMNIIGYDPYIPKEVAESMGVELVD------DINELCKRADFITLH 201

Query: 511 MTLNNESVGIVNHKFLSTLKKGSYLINIARGRLLDYTAVFNHLESGHLGGLGIDVAWTEP 332
           + L  ++  I+  + ++ +KK + ++N ARG L+D  A++  L+ G +    +DV   EP
Sbjct: 202 VPLTPKTRHIIGREQIALMKKNAIIVNCARGGLIDEKALYEALKEGKIRAAALDVFEEEP 261

Query: 331 FDPEDPILKFPNVIITPHIAGITEYSYRTMAKVVGDVALKLHAGE 197
              ++P+L   NVI TPH    TE + +    +V +   K+  GE
Sbjct: 262 -PKDNPLLTLDNVIGTPHQGASTEEAQKAAGTIVAEQIKKVLRGE 305

---

>SERA_METTH (O27051) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (PGDH)|
          Length = 525

 Score = 72.8 bits (177), Expect = 9e-13
 Identities = 49/176 (27%), Positives = 84/176 (47%), Gaps = 8/176 (4%)
 Frame = -1

Query: 691 GAIGMEIAKRLRPFGVKILATKRNWSSNTASCDLDGLVDKKGGPE------EMYELAREA 530
           G IG ++  R + FG+ I+               D  + K+   E      ++  L RE+
Sbjct: 150 GRIGSQVVVRTKAFGMDIMV-------------YDPYISKEAAEEMGVTVTDLETLLRES 196

Query: 529 DIVITCMTLNNESVGIVNHKFLSTLKKGSYLINIARGRLLDYTAVFNHLESGHLGGLGID 350
           DIV   + L  E+  +++      +K  ++++N ARG ++D  A++  L+ G + G  +D
Sbjct: 197 DIVTIHVPLTPETRHLISEDEFKLMKDTAFIVNCARGGIIDEDALYRALKDGEIAGAALD 256

Query: 349 VAWTEPFDPE-DPILKFPNVIITPHIAGITEYSYRTMAKVV-GDVALKLHAGEPFN 188
           V   EP  PE  P+L+  NV++TPHI   T  + R  A +V  ++      G P N
Sbjct: 257 VFEEEP--PEGSPLLELENVVLTPHIGASTSEAQRDAAIIVANEIKTVFQGGAPRN 310

---

>SERA_MYCLE (O33116) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (PGDH)|
          Length = 528

 Score = 71.2 bits (173), Expect = 3e-12
 Identities = 59/188 (31%), Positives = 91/188 (48%), Gaps = 3/188 (1%)
 Frame = -1

Query: 691 GAIGMEIAKRLRPFGVKILATKRNWSSNTASCDLDGLVDKKGGPEEMY--ELAREADIVI 518
           G IG  +A R+  FG  ++A     +   A+         + G E M   +L   AD + 
Sbjct: 150 GRIGQLVAARIAAFGAHVIAYDPYVAPARAA---------QLGIELMSFDDLLARADFIS 200

Query: 517 TCMTLNNESVGIVNHKFLSTLKKGSYLINIARGRLLDYTAVFNHLESGHLGGLGIDVAWT 338
             +    E+ G+++ + L+  K G  ++N ARG L+D  A+ + + SGH+   G+DV  T
Sbjct: 201 VHLPKTPETAGLIDKEALAKTKPGVIIVNAARGGLVDEVALADAVRSGHVRAAGLDVFAT 260

Query: 337 EPFDPEDPILKFPNVIITPHI-AGITEYSYRTMAKVVGDVALKLHAGEPFNEIEFVN*AK 161
           EP   + P+ +   V++TPH+ A   E   R    V   V L L AG      EFV  A 
Sbjct: 261 EPC-TDSPLFELSQVVVTPHLGASTAEAQDRAGTDVAESVRLAL-AG------EFVPDAV 312

Query: 160 *VDGGIVD 137
            VDGG+V+
Sbjct: 313 NVDGGVVN 320

---

>VANH_ENTFA (Q47748) D-specific alpha-keto acid dehydrogenase (EC 1.1.1.-)|
           (Vancomycin B-type resistance protein vanHB)
          Length = 323

 Score = 70.1 bits (170), Expect = 6e-12
 Identities = 51/159 (32%), Positives = 75/159 (47%), Gaps = 15/159 (9%)
 Frame = -1

Query: 691 GAIGMEIAKRLRPFGVKILATKRNWSSNTASCDLDGLVDKKGGPEEMYELAREADIVITC 512
           G IG  + KRLR FG ++LA   +         LD             EL + +DIV   
Sbjct: 156 GHIGQAVVKRLRGFGCRVLAYDNSRKIEADYVQLD-------------ELLKNSDIVTLH 202

Query: 511 MTLNNESVGIVNHKFLSTLKKGSYLINIARGRLLDYTAVFNHLESGHLGGLGIDVAWTE- 335
           + L  ++  ++  + +  +K+G++LIN  RG L+D  ++   L SG LGG  +DV   E 
Sbjct: 203 VPLCADTRHLIGQRQIGEMKQGAFLINTGRGALVDTGSLVEALGSGKLGGAALDVLEGED 262

Query: 334 --------------PFDPEDPILKFPNVIITPHIAGITE 260
                         PF  +  +L+ PNVIITPH A  TE
Sbjct: 263 QFVYTDCSQKVLDHPFLSQ--LLRMPNVIITPHTAYYTE 299

---

>SERA_MYCTU (P0A544) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (PGDH)|
          Length = 528

 Score = 68.9 bits (167), Expect = 1e-11
 Identities = 56/187 (29%), Positives = 90/187 (48%), Gaps = 2/187 (1%)
 Frame = -1

Query: 691 GAIGMEIAKRLRPFGVKILATKRNWS-SNTASCDLDGLVDKKGGPEEMYELAREADIVIT 515
           G IG  +A+R+  FG  ++A     S +  A   ++ L         + +L   AD +  
Sbjct: 150 GRIGQLVAQRIAAFGAYVVAYDPYVSPARAAQLGIELL--------SLDDLLARADFISV 201

Query: 514 CMTLNNESVGIVNHKFLSTLKKGSYLINIARGRLLDYTAVFNHLESGHLGGLGIDVAWTE 335
            +    E+ G+++ + L+  K G  ++N ARG L+D  A+ + +  GH+   G+DV  TE
Sbjct: 202 HLPKTPETAGLIDKEALAKTKPGVIIVNAARGGLVDEAALADAITGGHVRAAGLDVFATE 261

Query: 334 PFDPEDPILKFPNVIITPHI-AGITEYSYRTMAKVVGDVALKLHAGEPFNEIEFVN*AK* 158
           P   + P+ +   V++TPH+ A   E   R    V   V L L AG      EFV  A  
Sbjct: 262 PC-TDSPLFELAQVVVTPHLGASTAEAQDRAGTDVAESVRLAL-AG------EFVPDAVN 313

Query: 157 VDGGIVD 137
           V GG+V+
Sbjct: 314 VGGGVVN 320

---

>SERA_MYCBO (P0A545) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (PGDH)|
          Length = 528

 Score = 68.9 bits (167), Expect = 1e-11
 Identities = 56/187 (29%), Positives = 90/187 (48%), Gaps = 2/187 (1%)
 Frame = -1

Query: 691 GAIGMEIAKRLRPFGVKILATKRNWS-SNTASCDLDGLVDKKGGPEEMYELAREADIVIT 515
           G IG  +A+R+  FG  ++A     S +  A   ++ L         + +L   AD +  
Sbjct: 150 GRIGQLVAQRIAAFGAYVVAYDPYVSPARAAQLGIELL--------SLDDLLARADFISV 201

Query: 514 CMTLNNESVGIVNHKFLSTLKKGSYLINIARGRLLDYTAVFNHLESGHLGGLGIDVAWTE 335
            +    E+ G+++ + L+  K G  ++N ARG L+D  A+ + +  GH+   G+DV  TE
Sbjct: 202 HLPKTPETAGLIDKEALAKTKPGVIIVNAARGGLVDEAALADAITGGHVRAAGLDVFATE 261

Query: 334 PFDPEDPILKFPNVIITPHI-AGITEYSYRTMAKVVGDVALKLHAGEPFNEIEFVN*AK* 158
           P   + P+ +   V++TPH+ A   E   R    V   V L L AG      EFV  A  
Sbjct: 262 PC-TDSPLFELAQVVVTPHLGASTAEAQDRAGTDVAESVRLAL-AG------EFVPDAVN 313

Query: 157 VDGGIVD 137
           V GG+V+
Sbjct: 314 VGGGVVN 320

---

>SERA_SHIFL (P0A9T3) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (PGDH)|
          Length = 409

 Score = 68.6 bits (166), Expect = 2e-11
 Identities = 44/143 (30%), Positives = 73/143 (51%), Gaps = 5/143 (3%)
 Frame = -1

Query: 559 EEMYELAREADIVITCMTLNNESVGIVNHKFLSTLKKGSYLINIARGRLLDYTAVFNHLE 380
           + + +L   +D+V   +  N  +  ++  K +S +K GS LIN +RG ++D  A+ + L 
Sbjct: 194 QHLSDLLNMSDVVSLHVPENPSTKNMMGAKEISLMKPGSLLINASRGTVVDIPALCDALA 253

Query: 379 SGHLGGLGIDVAWTEPFDPED----PILKFPNVIITPHIAGITEYSYRTMA-KVVGDVAL 215
           S HL G  IDV  TEP    D    P+ +F NV++TPHI G T+ +   +  +V G +  
Sbjct: 254 SKHLAGAAIDVFPTEPATNSDPFTSPLCEFDNVLLTPHIGGSTQEAQENIGLEVAGKLIK 313

Query: 214 KLHAGEPFNEIEFVN*AK*VDGG 146
               G   + + F   +  + GG
Sbjct: 314 YSDNGSTLSAVNFPEVSLPLHGG 336

---

>SERA_ECOLI (P0A9T0) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (PGDH)|
          Length = 409

 Score = 68.6 bits (166), Expect = 2e-11
 Identities = 44/143 (30%), Positives = 73/143 (51%), Gaps = 5/143 (3%)
 Frame = -1

Query: 559 EEMYELAREADIVITCMTLNNESVGIVNHKFLSTLKKGSYLINIARGRLLDYTAVFNHLE 380
           + + +L   +D+V   +  N  +  ++  K +S +K GS LIN +RG ++D  A+ + L 
Sbjct: 194 QHLSDLLNMSDVVSLHVPENPSTKNMMGAKEISLMKPGSLLINASRGTVVDIPALCDALA 253

Query: 379 SGHLGGLGIDVAWTEPFDPED----PILKFPNVIITPHIAGITEYSYRTMA-KVVGDVAL 215
           S HL G  IDV  TEP    D    P+ +F NV++TPHI G T+ +   +  +V G +  
Sbjct: 254 SKHLAGAAIDVFPTEPATNSDPFTSPLCEFDNVLLTPHIGGSTQEAQENIGLEVAGKLIK 313

Query: 214 KLHAGEPFNEIEFVN*AK*VDGG 146
               G   + + F   +  + GG
Sbjct: 314 YSDNGSTLSAVNFPEVSLPLHGG 336

---

>SERA_ECOL6 (P0A9T1) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (PGDH)|
          Length = 409

 Score = 68.6 bits (166), Expect = 2e-11
 Identities = 44/143 (30%), Positives = 73/143 (51%), Gaps = 5/143 (3%)
 Frame = -1

Query: 559 EEMYELAREADIVITCMTLNNESVGIVNHKFLSTLKKGSYLINIARGRLLDYTAVFNHLE 380
           + + +L   +D+V   +  N  +  ++  K +S +K GS LIN +RG ++D  A+ + L 
Sbjct: 194 QHLSDLLNMSDVVSLHVPENPSTKNMMGAKEISLMKPGSLLINASRGTVVDIPALCDALA 253

Query: 379 SGHLGGLGIDVAWTEPFDPED----PILKFPNVIITPHIAGITEYSYRTMA-KVVGDVAL 215
           S HL G  IDV  TEP    D    P+ +F NV++TPHI G T+ +   +  +V G +  
Sbjct: 254 SKHLAGAAIDVFPTEPATNSDPFTSPLCEFDNVLLTPHIGGSTQEAQENIGLEVAGKLIK 313

Query: 214 KLHAGEPFNEIEFVN*AK*VDGG 146
               G   + + F   +  + GG
Sbjct: 314 YSDNGSTLSAVNFPEVSLPLHGG 336

---

>SERA_ECO57 (P0A9T2) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (PGDH)|
          Length = 409

 Score = 68.6 bits (166), Expect = 2e-11
 Identities = 44/143 (30%), Positives = 73/143 (51%), Gaps = 5/143 (3%)
 Frame = -1

Query: 559 EEMYELAREADIVITCMTLNNESVGIVNHKFLSTLKKGSYLINIARGRLLDYTAVFNHLE 380
           + + +L   +D+V   +  N  +  ++  K +S +K GS LIN +RG ++D  A+ + L 
Sbjct: 194 QHLSDLLNMSDVVSLHVPENPSTKNMMGAKEISLMKPGSLLINASRGTVVDIPALCDALA 253

Query: 379 SGHLGGLGIDVAWTEPFDPED----PILKFPNVIITPHIAGITEYSYRTMA-KVVGDVAL 215
           S HL G  IDV  TEP    D    P+ +F NV++TPHI G T+ +   +  +V G +  
Sbjct: 254 SKHLAGAAIDVFPTEPATNSDPFTSPLCEFDNVLLTPHIGGSTQEAQENIGLEVAGKLIK 313

Query: 214 KLHAGEPFNEIEFVN*AK*VDGG 146
               G   + + F   +  + GG
Sbjct: 314 YSDNGSTLSAVNFPEVSLPLHGG 336

---

>CTBP2_MOUSE (P56546) C-terminal-binding protein 2 (CtBP2)|
          Length = 445

 Score = 66.2 bits (160), Expect = 9e-11
 Identities = 43/149 (28%), Positives = 75/149 (50%), Gaps = 4/149 (2%)
 Frame = -1

Query: 694 FGAIGMEIAKRLRPFGVKILATKRNWSSNTASCDLDGLVDKKGGPEEMY---ELAREADI 524
           FG  G  +A R + FG  ++               DG +++  G + +Y   +L  ++D 
Sbjct: 188 FGRTGQAVAVRAKAFGFSVIFYDPYLQ--------DG-IERSLGVQRVYTLQDLLYQSDC 238

Query: 523 VITCMTLNNESVGIVNHKFLSTLKKGSYLINIARGRLLDYTAVFNHLESGHLGGLGIDVA 344
           V     LN  +  ++N   +  +++G++L+N ARG L+D  A+   L+ G + G  +DV 
Sbjct: 239 VSLHCNLNEHNHHLINDFTIKQMRQGAFLVNAARGGLVDEKALAQALKEGRIRGAALDVH 298

Query: 343 WTEPFD-PEDPILKFPNVIITPHIAGITE 260
            +EPF   + P+   PN+I TPH A  +E
Sbjct: 299 ESEPFSFAQGPLKDAPNLICTPHTAWYSE 327

---

>CTBP2_HUMAN (P56545) C-terminal-binding protein 2 (CtBP2)|
          Length = 445

 Score = 66.2 bits (160), Expect = 9e-11
 Identities = 43/149 (28%), Positives = 75/149 (50%), Gaps = 4/149 (2%)
 Frame = -1

Query: 694 FGAIGMEIAKRLRPFGVKILATKRNWSSNTASCDLDGLVDKKGGPEEMY---ELAREADI 524
           FG  G  +A R + FG  ++               DG +++  G + +Y   +L  ++D 
Sbjct: 188 FGRTGQAVAVRAKAFGFSVIFYDPYLQ--------DG-IERSLGVQRVYTLQDLLYQSDC 238

Query: 523 VITCMTLNNESVGIVNHKFLSTLKKGSYLINIARGRLLDYTAVFNHLESGHLGGLGIDVA 344
           V     LN  +  ++N   +  +++G++L+N ARG L+D  A+   L+ G + G  +DV 
Sbjct: 239 VSLHCNLNEHNHHLINDFTIKQMRQGAFLVNAARGGLVDEKALAQALKEGRIRGAALDVH 298

Query: 343 WTEPFD-PEDPILKFPNVIITPHIAGITE 260
            +EPF   + P+   PN+I TPH A  +E
Sbjct: 299 ESEPFSFAQGPLKDAPNLICTPHTAWYSE 327

---

>TKRA_BACSU (O32264) Probable 2-ketogluconate reductase (EC 1.1.1.215) (2KR)|
          Length = 325

 Score = 65.5 bits (158), Expect = 1e-10
 Identities = 43/166 (25%), Positives = 78/166 (46%), Gaps = 1/166 (0%)
 Frame = -1

Query: 691 GAIGMEIAKRLR-PFGVKILATKRNWSSNTASCDLDGLVDKKGGPEEMYELAREADIVIT 515
           G IG + A+R +  F +++L   R+    T     D +  K     E+  L  ++D ++ 
Sbjct: 157 GRIGEQAARRAKFGFDMEVLYHNRHRKQETE----DSIGVKYA---ELDTLLEQSDFILL 209

Query: 514 CMTLNNESVGIVNHKFLSTLKKGSYLINIARGRLLDYTAVFNHLESGHLGGLGIDVAWTE 335
              L +E+  ++  +    +K  +  +NI+RG+ +D  A+   L+ G + G G+DV   E
Sbjct: 210 ITPLTDETYHMIGEREFKLMKNSAIFVNISRGKTVDEKALIRALQEGWIRGAGLDVYEKE 269

Query: 334 PFDPEDPILKFPNVIITPHIAGITEYSYRTMAKVVGDVALKLHAGE 197
           P   ++P+L+  NV + PHI   T      M K   +  L    G+
Sbjct: 270 PVTQDNPLLQLDNVTLLPHIGSATAKVRFNMCKQAAENMLAAIQGQ 315

---

>SERA_SYNY3 (P73821) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (PGDH)|
          Length = 554

 Score = 65.1 bits (157), Expect = 2e-10
 Identities = 51/172 (29%), Positives = 82/172 (47%), Gaps = 4/172 (2%)
 Frame = -1

Query: 691 GAIGMEIAKRLRPFGVKILATKRNWSSNTASCDLDGLVDKKGGPEEMYELAREADIVITC 512
           G IG  +A   +  G+K+LA     S   A      LVD       +  L  EAD +   
Sbjct: 176 GKIGSHVAGVAKAMGMKLLAYDPFISQERADQIGCTLVD-------LDLLFSEADFITLH 228

Query: 511 MTLNNESVGIVNHKFLSTLKKGSYLINIARGRLLDYTAVFNHLESGHLGGLGIDVAWTEP 332
           +    E+  ++N + L+ +K  + +IN +RG ++D  A+   +E+  +GG  +DV   EP
Sbjct: 229 IPKTPETANLINAETLAKMKPTARIINCSRGGIIDEEALVTAIETAQIGGAALDVFAQEP 288

Query: 331 FDPEDPILKFPNVIITPHIAGITEYSYRT----MAKVVGDVALKLHAGEPFN 188
              E  + +F NVI+TPH+   TE +       +A+ + DV L L A    N
Sbjct: 289 LG-ESRLREFSNVILTPHLGASTEEAQVNVAVDVAEQIRDVLLGLPARSAVN 339

---

>TKRA_ENTAG (P58000) 2-ketogluconate reductase (EC 1.1.1.215) (2KR)|
           (2-ketoaldonate reductase)
          Length = 323

 Score = 64.7 bits (156), Expect = 3e-10
 Identities = 48/172 (27%), Positives = 77/172 (44%), Gaps = 7/172 (4%)
 Frame = -1

Query: 691 GAIGMEIAKRLRP-FGVKILATKRNWSSNTAS------CDLDGLVDKKGGPEEMYELARE 533
           G IG+ +A+R    FG+ IL   R       S      CDLD L+             RE
Sbjct: 153 GRIGLALAQRAHHGFGMPILYNARKHHEEAESRFNAQYCDLDTLL-------------RE 199

Query: 532 ADIVITCMTLNNESVGIVNHKFLSTLKKGSYLINIARGRLLDYTAVFNHLESGHLGGLGI 353
           +D +   + L  ++  ++  + L+ +K  + LIN  RG ++D  A+   L+   +   G+
Sbjct: 200 SDFLCISLPLTEQTHHMIGREQLAKMKPSAILINAGRGPVVDEQALIAALKDKTIHAAGL 259

Query: 352 DVAWTEPFDPEDPILKFPNVIITPHIAGITEYSYRTMAKVVGDVALKLHAGE 197
           DV   EP   +  +L  PNV+  PHI   T  +   MA+   D  +   AG+
Sbjct: 260 DVFEQEPLPVDSELLTLPNVVALPHIGSATHETRYGMARDAVDNLIAALAGK 311

---

>PTXD_PSEST (O69054) Phosphonate dehydrogenase (EC 1.20.1.1) (NAD-dependent|
           phosphite dehydrogenase)
          Length = 336

 Score = 64.3 bits (155), Expect = 3e-10
 Identities = 48/148 (32%), Positives = 76/148 (51%), Gaps = 9/148 (6%)
 Frame = -1

Query: 691 GAIGMEIAKRLRPFGVKILATKRNWSSNTASCDLDGLVDKKGGPEEMY--ELAREADIVI 518
           GAIG+ +A RL+ +G    AT +   +      LD   +++ G  ++   EL   +D ++
Sbjct: 154 GAIGLAMADRLQGWG----ATLQYHEAKA----LDTQTEQRLGLRQVACSELFASSDFIL 205

Query: 517 TCMTLNNESVGIVNHKFLSTLKKGSYLINIARGRLLDYTAVFNHLESGHLGGLGIDV--- 347
             + LN ++  +VN + L+ ++ G+ L+N  RG ++D  AV   LE G LGG   DV   
Sbjct: 206 LALPLNADTQHLVNAELLALVRPGALLVNPCRGSVVDEAAVLAALERGQLGGYAADVFEM 265

Query: 346 -AWTEPFDPE--DP-ILKFPNVIITPHI 275
             W     P   DP +L  PN + TPHI
Sbjct: 266 EDWARADRPRLIDPALLAHPNTLFTPHI 293

---

>FDH_NEUCR (Q07103) Formate dehydrogenase (EC 1.2.1.2) (NAD-dependent formate|
           dehydrogenase) (FDH)
          Length = 375

 Score = 64.3 bits (155), Expect = 3e-10
 Identities = 42/146 (28%), Positives = 74/146 (50%), Gaps = 5/146 (3%)
 Frame = -1

Query: 691 GAIGMEIAKRLRPFGVKILATKRNWSSNTASCDLDGLVDKKGGPEEMYELAREADIVITC 512
           G IG  + +RL+PF  K L     +     S + +  +  +    ++ E+  + D+V   
Sbjct: 174 GRIGERVLRRLKPFDCKELLY---YDYQPLSAEKEAEIGCRR-VADLEEMLAQCDVVTIN 229

Query: 511 MTLNNESVGIVNHKFLSTLKKGSYLINIARGRLLDYTAVFNHLESGHLGGLGIDVAWTEP 332
             L+ ++ G+ N + +S +KKGS+L+N ARG ++    V   L+SGHL G G DV + +P
Sbjct: 230 CPLHEKTQGLFNKELISKMKKGSWLVNTARGAIVVKEDVAEALKSGHLRGYGGDVWFPQP 289

Query: 331 FDPEDPILKFPNVI-----ITPHIAG 269
              + P+    N       + PH++G
Sbjct: 290 APQDHPLRYAKNPFGGGNAMVPHMSG 315

---

>TKRA_ECOLI (P37666) 2-ketogluconate reductase (EC 1.1.1.215) (2KR)|
           (2-ketoaldonate reductase)
          Length = 324

 Score = 63.9 bits (154), Expect = 4e-10
 Identities = 46/163 (28%), Positives = 70/163 (42%), Gaps = 7/163 (4%)
 Frame = -1

Query: 691 GAIGMEIAKRLR-PFGVKILATKRNWSS------NTASCDLDGLVDKKGGPEEMYELARE 533
           G IGM +A+R    F + IL   R          N   CDLD L+             +E
Sbjct: 154 GRIGMALAQRAHFGFNMPILYNARRHHKEAEERFNARYCDLDTLL-------------QE 200

Query: 532 ADIVITCMTLNNESVGIVNHKFLSTLKKGSYLINIARGRLLDYTAVFNHLESGHLGGLGI 353
           +D V   + L +E+  +   +  + +K  +  IN  RG ++D  A+   L+ G +   G+
Sbjct: 201 SDFVCLILPLTDETHHLFGAEQFAKMKSSAIFINAGRGPVVDENALIAALQKGEIHAAGL 260

Query: 352 DVAWTEPFDPEDPILKFPNVIITPHIAGITEYSYRTMAKVVGD 224
           DV   EP   + P+L   NV+  PHI   T  +   MA    D
Sbjct: 261 DVFEQEPLSVDSPLLSMANVVAVPHIGSATHETRYGMAACAVD 303

---

>TKRA_ECO57 (P58220) 2-ketogluconate reductase (EC 1.1.1.215) (2KR)|
           (2-ketoaldonate reductase)
          Length = 324

 Score = 63.9 bits (154), Expect = 4e-10
 Identities = 46/163 (28%), Positives = 70/163 (42%), Gaps = 7/163 (4%)
 Frame = -1

Query: 691 GAIGMEIAKRLR-PFGVKILATKRNWSS------NTASCDLDGLVDKKGGPEEMYELARE 533
           G IGM +A+R    F + IL   R          N   CDLD L+             +E
Sbjct: 154 GRIGMALAQRAHFGFNMPILYNARRHHKEAEERFNARYCDLDTLL-------------QE 200

Query: 532 ADIVITCMTLNNESVGIVNHKFLSTLKKGSYLINIARGRLLDYTAVFNHLESGHLGGLGI 353
           +D V   + L +E+  +   +  + +K  +  IN  RG ++D  A+   L+ G +   G+
Sbjct: 201 SDFVCLILPLTDETHHLFGAEQFAKMKSSAIFINAGRGPVVDENALIAALQKGEIHAAGL 260

Query: 352 DVAWTEPFDPEDPILKFPNVIITPHIAGITEYSYRTMAKVVGD 224
           DV   EP   + P+L   NV+  PHI   T  +   MA    D
Sbjct: 261 DVFEQEPLSVDSPLLSMANVVAVPHIGSATHETRYGMAACAVD 303

---

>SERA_ARATH (O04130) D-3-phosphoglycerate dehydrogenase, chloroplast precursor|
           (EC 1.1.1.95) (3-PGDH)
          Length = 624

 Score = 63.5 bits (153), Expect = 6e-10
 Identities = 43/166 (25%), Positives = 77/166 (46%)
 Frame = -1

Query: 694 FGAIGMEIAKRLRPFGVKILATKRNWSSNTASCDLDGLVDKKGGPEEMYELAREADIVIT 515
           FG +G E+A+R +  G+ +++      ++ A      LV          +    AD V  
Sbjct: 229 FGKVGTEVARRAKGLGMTVISHDPYAPADRARALGVDLVS-------FDQAISTADFVSL 281

Query: 514 CMTLNNESVGIVNHKFLSTLKKGSYLINIARGRLLDYTAVFNHLESGHLGGLGIDVAWTE 335
            M L   +  + N +  S +KKG  LIN+ARG ++D  A+   L++G +    +DV   E
Sbjct: 282 HMPLTPATKKVFNDETFSKMKKGVRLINVARGGVIDEDALVRALDAGIVAQAALDVFCEE 341

Query: 334 PFDPEDPILKFPNVIITPHIAGITEYSYRTMAKVVGDVALKLHAGE 197
           P   +  +++  NV +TPH+   T+ +   +A  + +       GE
Sbjct: 342 PPSKDSRLIQHENVTVTPHLGASTKEAQEGVAIEIAEAVAGALKGE 387

---

>CTBPB_XENLA (Q9W758) C-terminal-binding protein B (TCF-3 corepressor CtBP)|
           (XCtBP)
          Length = 437

 Score = 63.2 bits (152), Expect = 7e-10
 Identities = 43/150 (28%), Positives = 74/150 (49%), Gaps = 4/150 (2%)
 Frame = -1

Query: 691 GAIGMEIAKRLRPFGVKILATKRNWSSNTASCDLDGLVDKKGGPEEM---YELAREADIV 521
           G IG  +A R + F   ++      +        DG V++  G + M    EL   +D +
Sbjct: 186 GRIGQAVALRAKAFNFTVIFYDPYLA--------DG-VERSLGLQRMATLQELLMHSDCI 236

Query: 520 ITCMTLNNESVGIVNHKFLSTLKKGSYLINIARGRLLDYTAVFNHLESGHLGGLGIDVAW 341
                LN  +  ++N   +  +++G +L+N ARG L+D  A+   L+ G + G  +DV  
Sbjct: 237 TLHCNLNEHNHHLINDFTIKQMRQGCFLVNTARGGLVDEKALAQALKDGRIRGAALDVHE 296

Query: 340 TEPFD-PEDPILKFPNVIITPHIAGITEYS 254
           +EPF   + P+   PN+I TPH A  +E++
Sbjct: 297 SEPFSFSQGPLKDAPNLICTPHTAWYSEHA 326

---

>CTBP1_MOUSE (O88712) C-terminal-binding protein 1 (EC 1.1.1.-) (CtBP1)|
          Length = 440

 Score = 63.2 bits (152), Expect = 7e-10
 Identities = 43/147 (29%), Positives = 71/147 (48%), Gaps = 3/147 (2%)
 Frame = -1

Query: 691 GAIGMEIAKRLRPFGVKILATKRNWSSNTASCDLDGLVDKKG--GPEEMYELAREADIVI 518
           G +G  +A R + FG  +L      S        DG+    G      + +L   +D V 
Sbjct: 183 GRVGQAVALRAKAFGFNVLFYDPYLS--------DGIERALGLQRVSTLQDLLFHSDCVT 234

Query: 517 TCMTLNNESVGIVNHKFLSTLKKGSYLINIARGRLLDYTAVFNHLESGHLGGLGIDVAWT 338
               LN  +  ++N   +  +++G++L+N ARG L+D  A+   L+ G + G  +DV  +
Sbjct: 235 LHCGLNEHNHHLINDFTVKQMRQGAFLVNTARGGLVDEKALAQALKEGRIRGAALDVHES 294

Query: 337 EPFD-PEDPILKFPNVIITPHIAGITE 260
           EPF   + P+   PN+I TPH A  +E
Sbjct: 295 EPFSFSQGPLKDAPNLICTPHAAWYSE 321

---

>CTBP1_RAT (Q9Z2F5) C-terminal-binding protein 1 (EC 1.1.1.-) (CtBP1)|
           (C-terminal-binding protein 3) (CtBP3) (50 kDa
           BFA-dependent ADP-ribosylation substrate) (BARS-50)
          Length = 430

 Score = 63.2 bits (152), Expect = 7e-10
 Identities = 43/147 (29%), Positives = 71/147 (48%), Gaps = 3/147 (2%)
 Frame = -1

Query: 691 GAIGMEIAKRLRPFGVKILATKRNWSSNTASCDLDGLVDKKG--GPEEMYELAREADIVI 518
           G +G  +A R + FG  +L      S        DG+    G      + +L   +D V 
Sbjct: 172 GRVGQAVALRAKAFGFNVLFYDPYLS--------DGIERALGLQRVSTLQDLLFHSDCVT 223

Query: 517 TCMTLNNESVGIVNHKFLSTLKKGSYLINIARGRLLDYTAVFNHLESGHLGGLGIDVAWT 338
               LN  +  ++N   +  +++G++L+N ARG L+D  A+   L+ G + G  +DV  +
Sbjct: 224 LHCGLNEHNHHLINDFTVKQMRQGAFLVNTARGGLVDEKALAQALKEGRIRGAALDVHES 283

Query: 337 EPFD-PEDPILKFPNVIITPHIAGITE 260
           EPF   + P+   PN+I TPH A  +E
Sbjct: 284 EPFSFSQGPLKDAPNLICTPHAAWYSE 310

---

>DHGY_CUCSA (P13443) Glycerate dehydrogenase (EC 1.1.1.29) (NADH-dependent|
           hydroxypyruvate reductase) (HPR) (GDH)
          Length = 382

 Score = 62.8 bits (151), Expect = 1e-09
 Identities = 35/105 (33%), Positives = 59/105 (56%)
 Frame = -1

Query: 553 MYELAREADIVITCMTLNNESVGIVNHKFLSTLKKGSYLINIARGRLLDYTAVFNHLESG 374
           M E+ READ++     L+  +  +VN + L  +KK + LIN +RG ++D  A+ +HL   
Sbjct: 230 MDEVLREADVISLHPVLDKTTFHLVNKESLKAMKKDAILINCSRGPVIDEAALVDHLRDN 289

Query: 373 HLGGLGIDVAWTEPFDPEDPILKFPNVIITPHIAGITEYSYRTMA 239
            +  +G+DV   EP+  +  +    N II PHIA  ++++   MA
Sbjct: 290 PMFRVGLDVFEDEPY-MKPGLADMKNAIIVPHIASASKWTREGMA 333

---

>CTBP1_HUMAN (Q13363) C-terminal-binding protein 1 (EC 1.1.1.-) (CtBP1)|
          Length = 440

 Score = 62.8 bits (151), Expect = 1e-09
 Identities = 43/147 (29%), Positives = 71/147 (48%), Gaps = 3/147 (2%)
 Frame = -1

Query: 691 GAIGMEIAKRLRPFGVKILATKRNWSSNTASCDLDGLVDKKG--GPEEMYELAREADIVI 518
           G +G  +A R + FG  +L      S        DG+    G      + +L   +D V 
Sbjct: 183 GRVGQAVALRAKAFGFNVLFYDPYLS--------DGVERALGLQRVSTLQDLLFHSDCVT 234

Query: 517 TCMTLNNESVGIVNHKFLSTLKKGSYLINIARGRLLDYTAVFNHLESGHLGGLGIDVAWT 338
               LN  +  ++N   +  +++G++L+N ARG L+D  A+   L+ G + G  +DV  +
Sbjct: 235 LHCGLNEHNHHLINDFTVKQMRQGAFLVNTARGGLVDEKALAQALKEGRIRGAALDVHES 294

Query: 337 EPFD-PEDPILKFPNVIITPHIAGITE 260
           EPF   + P+   PN+I TPH A  +E
Sbjct: 295 EPFSFSQGPLKDAPNLICTPHAAWYSE 321

---

>LDHD_STRP1 (Q99ZM2) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific|
           D-2-hydroxyacid dehydrogenase)
          Length = 330

 Score = 62.4 bits (150), Expect = 1e-09
 Identities = 46/165 (27%), Positives = 79/165 (47%), Gaps = 13/165 (7%)
 Frame = -1

Query: 691 GAIGMEIAKRLRPFGVKILATKRNWSSNTASCDLDGLVDKKGGPEEMYELAREADIVITC 512
           G IG+  AK  + FG K++     + S+ A   LD         E + E  ++AD+V   
Sbjct: 154 GRIGLATAKIFKGFGCKVVGYDI-YQSDAAKAVLDY-------KESVEEAIKDADLVSLH 205

Query: 511 MTLNNESVGIVNHKFLSTLKKGSYLINIARGRLLDYTAVFNHLESGHLGGLGIDVAWTE- 335
           M    E+  + N     + KKG+ L+N+ARG +++   + + L++G L G GID    E 
Sbjct: 206 MPPTAENTHLFNSDLFKSFKKGAILMNMARGAVIETQDLLDALDAGLLSGAGIDTYEFEG 265

Query: 334 PFDPED------------PILKFPNVIITPHIAGITEYSYRTMAK 236
           P+ P++             ++  P VI TPH A  T+ + + + +
Sbjct: 266 PYIPKNFEGQEITDSLFKALINHPKVIYTPHAAYYTDEAVKNLVE 310

---

>CTBPA_XENLA (Q9YHU0) C-terminal-binding protein A (CtBP)|
          Length = 440

 Score = 62.0 bits (149), Expect = 2e-09
 Identities = 42/147 (28%), Positives = 70/147 (47%), Gaps = 3/147 (2%)
 Frame = -1

Query: 691 GAIGMEIAKRLRPFGVKILATKRNWSSNTASCDLDGLVDKKG--GPEEMYELAREADIVI 518
           G +G  +A R + FG  +       S        DG+    G      + +L   +D V 
Sbjct: 183 GRVGQAVALRAKTFGFNVFFYDPYLS--------DGIERALGLQRVSTLQDLLFHSDCVT 234

Query: 517 TCMTLNNESVGIVNHKFLSTLKKGSYLINIARGRLLDYTAVFNHLESGHLGGLGIDVAWT 338
               LN  +  ++N   +  +++G++L+N ARG L+D  A+   L+ G + G  +DV  +
Sbjct: 235 LHCGLNEHNHHLINDFTIKQMRQGAFLVNTARGGLVDEKALAQALKEGRIRGAALDVHES 294

Query: 337 EPFD-PEDPILKFPNVIITPHIAGITE 260
           EPF   + P+   PN+I TPH A  +E
Sbjct: 295 EPFSFTQGPLKDAPNLICTPHAAWYSE 321

---

>DHD2_LACPA (P17584) D-2-hydroxyisocaproate dehydrogenase (EC 1.1.1.-)|
           (D-HICDH)
          Length = 333

 Score = 60.8 bits (146), Expect = 4e-09
 Identities = 48/167 (28%), Positives = 78/167 (46%), Gaps = 17/167 (10%)
 Frame = -1

Query: 691 GAIGMEIAKRLRPFGVKILATKRNWSSNTASCDLDGLVDKKGGPEEMY----ELAREADI 524
           G IG    K  + FG K++A              D    K   P+  Y    +L +++D+
Sbjct: 154 GHIGQVAIKLFKGFGAKVIA-------------YDPYPMKGDHPDFDYVSLEDLFKQSDV 200

Query: 523 VITCMTLNNESVGIVNHKFLSTLKKGSYLINIARGRLLDYTAVFNHLESGHLGGLGIDVA 344
           +   +    ++  I+N    + +K G+ +IN AR  L+D  A+ ++L+SG L G+GID  
Sbjct: 201 IDLHVPGIEQNTHIINEAAFNLMKPGAIVINTARPNLIDTQAMLSNLKSGKLAGVGIDTY 260

Query: 343 WTEPFDP---------EDP----ILKFPNVIITPHIAGITEYSYRTM 242
             E  D          +DP    +L  PNV+++PHIA  TE +   M
Sbjct: 261 EYETEDLLNLAKHGSFKDPLWDELLGMPNVVLSPHIAYYTETAVHNM 307

---

>LDHD_TREPA (O83080) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific|
           D-2-hydroxyacid dehydrogenase)
          Length = 331

 Score = 60.5 bits (145), Expect = 5e-09
 Identities = 39/133 (29%), Positives = 63/133 (47%), Gaps = 13/133 (9%)
 Frame = -1

Query: 553 MYELAREADIVITCMTLNNESVGIVNHKFLSTLKKGSYLINIARGRLLDYTAVFNHLESG 374
           M EL   +D++   M    +S  ++N K ++ +K G YL+N ARG ++D  A+ + L+ G
Sbjct: 192 MDELLSTSDVISLHMPATKDSHHLINAKTIAQMKDGVYLVNTARGAVIDSQALLDSLDKG 251

Query: 373 HLGGLGIDVAWTE-PFDPED------------PILKFPNVIITPHIAGITEYSYRTMAKV 233
            + G  +D    E P+ P+D             ++    +I TPHIA  TE +   M   
Sbjct: 252 KIAGAALDAYEFEGPYIPKDNGNNPITDTVYARLVAHERIIYTPHIAFYTETAIENMVFN 311

Query: 232 VGDVALKLHAGEP 194
             D    +  GEP
Sbjct: 312 SLDACTTVLRGEP 324

---

>YGDH_SCHPO (O94574) Putative 2-hydroxyacid dehydrogenase C1773.17c (EC|
           1.-.-.-)
          Length = 340

 Score = 60.1 bits (144), Expect = 6e-09
 Identities = 47/173 (27%), Positives = 78/173 (45%), Gaps = 3/173 (1%)
 Frame = -1

Query: 691 GAIGMEIAKRLRPFGVKILATKRNWSSNTASCDLDGLVDKKGGPE--EMYELAREADIVI 518
           GAIG   A+++ P G +I+   RN         L+   +K+ G       EL   +D++ 
Sbjct: 168 GAIGKSFAQKILPLGCEIVYHNRN--------RLEAEEEKRLGASFVSFDELLSSSDVIS 219

Query: 517 TCMTLNNESVGIVNHKFLSTLKKGSYLINIARGRLLDYTAVFNHLESGHLGGLGIDVAWT 338
               L   +  +++ K    +K G Y+IN ARG +++  A    ++SG +   G+DV   
Sbjct: 220 INCPLTPATHDLISTKEFEKMKDGVYIINTARGAIINEDAFIKAIKSGKVARAGLDVFLN 279

Query: 337 EPFDPEDPILKFPNVIITPHIAGITEYSY-RTMAKVVGDVALKLHAGEPFNEI 182
           EP  P    L+   V I PH    T ++  +T   V+  +   L  G P N +
Sbjct: 280 EP-TPNKFWLECDKVTIQPHCGVYTNFTVAKTEECVLASIETFLDTGIPTNPV 331

---

>LDHD_LACHE (P30901) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific|
           D-2-hydroxyacid dehydrogenase)
          Length = 336

 Score = 59.3 bits (142), Expect = 1e-08
 Identities = 48/179 (26%), Positives = 84/179 (46%), Gaps = 14/179 (7%)
 Frame = -1

Query: 691 GAIGMEIAKRLRPFGVKILATKRNWSSNTASCDLDGLVDKKGG-PEEMYELAREADIVIT 515
           G IG    + +  FG K++A     +           ++KKG   + + +L ++AD++  
Sbjct: 154 GHIGQVFMRIMEGFGAKVIAYDIFKNPE---------LEKKGYYVDSLDDLYKQADVISL 204

Query: 514 CMTLNNESVGIVNHKFLSTLKKGSYLINIARGRLLDYTAVFNHLESGHLGGLGIDV---- 347
            +     +V ++N K ++ +K G  ++N +RGRL+D  AV   L+SG + G  +D     
Sbjct: 205 HVPDVPANVHMINDKSIAEMKDGVVIVNCSRGRLVDTDAVIRGLDSGKIFGFVMDTYEDE 264

Query: 346 ------AWTEPFDPED---PILKFPNVIITPHIAGITEYSYRTMAKVVGDVALKLHAGE 197
                  W     P+     ++  PNV++TPH A  T ++ R M     +  LKL  GE
Sbjct: 265 VGVFNKDWEGKEFPDKRLADLIDRPNVLVTPHTAFYTTHAVRNMVVKAFNNNLKLINGE 323

---

>SERA_HAEIN (P43885) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (PGDH)|
          Length = 410

 Score = 58.9 bits (141), Expect = 1e-08
 Identities = 40/129 (31%), Positives = 62/129 (48%), Gaps = 5/129 (3%)
 Frame = -1

Query: 547 ELAREADIVITCMTLNNESVGIVNHKFLSTLKKGSYLINIARGRLLDYTAVFNHLESGHL 368
           EL    D+V   +     +  ++N   ++ LK+G+ LIN ARG ++D  A+   L+ G L
Sbjct: 200 ELLSSCDVVSLHVPELPSTKNLMNVARIAQLKQGAILINAARGTVVDIDALAQALKDGKL 259

Query: 367 GGLGIDVAWTEPFDPED----PILKFPNVIITPHIAGITEYSYRTMA-KVVGDVALKLHA 203
            G  IDV   EP    +    P+ +F NVI+TPHI G T  +   +  +V G        
Sbjct: 260 QGAAIDVFPVEPASINEEFISPLREFDNVILTPHIGGSTAEAQENIGFEVAGKFVKYSDN 319

Query: 202 GEPFNEIEF 176
           G   + + F
Sbjct: 320 GSTLSSVNF 328

---

>CTBP_DROME (O46036) C-terminal-binding protein (CtBP protein) (dCtBP)|
          Length = 476

 Score = 58.5 bits (140), Expect = 2e-08
 Identities = 44/150 (29%), Positives = 72/150 (48%), Gaps = 4/150 (2%)
 Frame = -1

Query: 691 GAIGMEIAKRLRPFGVKILATKRNWSSNTASCDLDGLVDKKGGPEEMY---ELAREADIV 521
           G IG  +A R + FG  ++               DG +DK  G   +Y   +L  ++D V
Sbjct: 183 GRIGSAVALRAKAFGFNVIFYDPYLP--------DG-IDKSLGLTRVYTLQDLLFQSDCV 233

Query: 520 ITCMTLNNESVGIVNHKFLSTLKKGSYLINIARGRLLDYTAVFNHLESGHLGGLGIDVAW 341
               TLN  +  ++N   +  ++ G++L+N ARG L+D   +   L+ G +    +DV  
Sbjct: 234 SLHCTLNEHNHHLINEFTIKQMRPGAFLVNTARGGLVDDETLALALKQGRIRAAALDVHE 293

Query: 340 TEPFDPEDPILK-FPNVIITPHIAGITEYS 254
            EP++     LK  PN+I TPH A  ++ S
Sbjct: 294 NEPYNVFQGALKDAPNLICTPHAAFFSDAS 323

---

>DDH_ZYMMO (P30799) 2-hydroxyacid dehydrogenase homolog (EC 1.1.1.-)|
          Length = 331

 Score = 58.5 bits (140), Expect = 2e-08
 Identities = 41/116 (35%), Positives = 61/116 (52%), Gaps = 13/116 (11%)
 Frame = -1

Query: 547 ELAREADIVITCMTLNNESVGIVNHKFLSTLKKGSYLINIARGRLLDYTAVFNHLESGHL 368
           E+   +DI+     L  E+  ++N + L+  KKG YL+N +RG L+D  AV   L++ HL
Sbjct: 195 EVIETSDIISLHCPLTPENHHMINEETLARAKKGFYLVNTSRGGLVDTKAVIKSLKAKHL 254

Query: 367 GGLGIDVAWTEP---FDP------EDPILK----FPNVIITPHIAGITEYSYRTMA 239
           GG   DV   E    F+       ED IL+    FPNV+ T H A +T+ +   +A
Sbjct: 255 GGYAADVYEEEGPLFFENHADDIIEDDILERLIAFPNVVFTGHQAFLTKEALSNIA 310

---

>SERA_SCHPO (P87228) Putative D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95)|
           (3-PGDH)
          Length = 466

 Score = 58.5 bits (140), Expect = 2e-08
 Identities = 38/137 (27%), Positives = 65/137 (47%), Gaps = 13/137 (9%)
 Frame = -1

Query: 547 ELAREADIVITCMTLNNESVGIVNHKFLSTLKKGSYLINIARGRLLDYTAVFNHLESGHL 368
           EL   AD V   +  + E+  +++ K  + +K+GSYLIN +RG ++D  A+ +  +SG +
Sbjct: 243 ELLHRADFVSLHVPASPETKNMISSKEFAAMKEGSYLINASRGTVVDIPALVDASKSGKI 302

Query: 367 GGLGIDVAWTEPFDP------------EDPILKFPNVIITPHIAGITEYSYRTMAKVVGD 224
            G  IDV  +EP                  +    N+I+TPHI G TE +   +   V +
Sbjct: 303 AGAAIDVYPSEPAGNGKDKFVDSLNSWTSELTHCKNIILTPHIGGSTEEAQYNIGIEVSE 362

Query: 223 VALK-LHAGEPFNEIEF 176
              + ++ G     + F
Sbjct: 363 ALTRYINEGNSIGAVNF 379

---

>LDHD_STRA5 (Q8E0N5) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific|
           D-2-hydroxyacid dehydrogenase)
          Length = 330

 Score = 58.2 bits (139), Expect = 2e-08
 Identities = 46/165 (27%), Positives = 75/165 (45%), Gaps = 13/165 (7%)
 Frame = -1

Query: 691 GAIGMEIAKRLRPFGVKILATKRNWSSNTASCDLDGLVDKKGGPEEMYELAREADIVITC 512
           G IG+  AK  + FG +++      +        DG+++     EE  E   EAD+V   
Sbjct: 154 GRIGLATAKIFKGFGCRVIGYDIYHNPMA-----DGILEYVNSVEEAVE---EADLVSLH 205

Query: 511 MTLNNESVGIVNHKFLSTLKKGSYLINIARGRLLDYTAVFNHLESGHLGGLGIDVAWTE- 335
           M    E+  + N       KKG+ L+N+ARG L++   +   L+ G L G GID    E 
Sbjct: 206 MPPTAENTHLFNLDMFKQFKKGAILMNMARGALVETKDLLEALDQGLLEGAGIDTYEFEG 265

Query: 334 PFDPED------------PILKFPNVIITPHIAGITEYSYRTMAK 236
           P+ P++             ++  P VI TPH A  T+ + + + +
Sbjct: 266 PYIPKNCQGQDISDKDFLRLINHPKVIYTPHAAYYTDEAVKNLVE 310

---

>FDH2_YEAST (Q08987) Formate dehydrogenase 2 (EC 1.2.1.2) (NAD-dependent|
           formate dehydrogenase 2)
          Length = 376

 Score = 57.8 bits (138), Expect = 3e-08
 Identities = 47/170 (27%), Positives = 79/170 (46%), Gaps = 13/170 (7%)
 Frame = -1

Query: 691 GAIGMEIAKRLRPFGVKILA--------TKRNWSSNTASCDLDGLVDKKGGPEEMYELAR 536
           G IG  + +RL  F  K L          +     N AS   +G  D     E++ ++  
Sbjct: 175 GRIGYRVLERLVAFNPKKLLYYDYQELPAEAINRLNEASKLFNGRGDIVQRVEKLEDMVA 234

Query: 535 EADIVITCMTLNNESVGIVNHKFLSTLKKGSYLINIARGRLLDYTAVFNHLESGHLGGLG 356
           ++D+V     L+ +S G+ N K +S +K G+YL+N ARG +     V   ++SG L G G
Sbjct: 235 QSDVVTINCPLHKDSRGLFNKKLISHMKDGAYLVNTARGAICVAEDVAEAVKSGKLAGYG 294

Query: 355 IDVAWTEPFDPEDPILKFPNV-----IITPHIAGITEYSYRTMAKVVGDV 221
            DV   +P   + P     N       +T HI+G + ++ +  A+ V ++
Sbjct: 295 GDVWDKQPAPKDHPWRTMDNKDHVGNAMTVHISGTSLHAQKRYAQGVKNI 344

---

>LDHD_LACDE (P26297) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific|
           D-2-hydroxyacid dehydrogenase)
          Length = 332

 Score = 57.0 bits (136), Expect = 5e-08
 Identities = 47/180 (26%), Positives = 84/180 (46%), Gaps = 15/180 (8%)
 Frame = -1

Query: 691 GAIGMEIAKRLRPFGVKILATK--RNWSSNTASCDLDGLVDKKGGPEEMYELAREADIVI 518
           G IG    + +  FG K++A    RN         +D L D          L ++AD++ 
Sbjct: 154 GHIGQVFMQIMEGFGAKVIAYDIFRNPELEKKGYYVDSLDD----------LYKQADVIS 203

Query: 517 TCMTLNNESVGIVNHKFLSTLKKGSYLINIARGRLLDYTAVFNHLESGHLGGLGIDV--- 347
             +     +V ++N K ++ +K+   ++N++RG L+D  AV   L+SG + G  +DV   
Sbjct: 204 LHVPDVPANVHMINDKSIAKMKQDVVIVNVSRGPLVDTDAVIRGLDSGKVFGYAMDVYEG 263

Query: 346 ---AWTEPFDPED-------PILKFPNVIITPHIAGITEYSYRTMAKVVGDVALKLHAGE 197
               + E  + ++        ++  PNV++TPH A  T ++ R M     D  L+L  G+
Sbjct: 264 EVGVFNEDREGKEFPDARLADLIARPNVLVTPHTAFYTTHAVRNMVVKAFDNNLELVEGK 323

---

>SERA_RAT (O08651) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (3-PGDH)|
          Length = 532

 Score = 56.6 bits (135), Expect = 7e-08
 Identities = 43/145 (29%), Positives = 69/145 (47%), Gaps = 1/145 (0%)
 Frame = -1

Query: 691 GAIGMEIAKRLRPFGVKILATKRNWSSNTASCDLDGLVDKKGGPEEMYELAREADIVITC 512
           G IG E+A R++ FG+K +      S   A+        ++   EE++ L    D +   
Sbjct: 153 GRIGREVAARMQAFGMKTVGYDPIISPEVAA----SFGVQQLPLEEIWPLC---DFITVH 205

Query: 511 MTLNNESVGIVNHKFLSTLKKGSYLINIARGRLLDYTAVFNHLESGHLGGLGIDVAWTEP 332
             L   + G++N    +  KKG  ++N ARG ++D  A+   L+SG   G  +DV   EP
Sbjct: 206 TPLLPSTTGLLNDSTFAQCKKGVRVVNCARGGIVDEGALLRALQSGQCAGAALDVFTEEP 265

Query: 331 FDPED-PILKFPNVIITPHIAGITE 260
             P D  ++   NVI  PH+   T+
Sbjct: 266 --PRDRALVDHENVISCPHLGASTK 288

---

>SERA_MOUSE (Q61753) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (3-PGDH)|
           (A10)
          Length = 532

 Score = 56.6 bits (135), Expect = 7e-08
 Identities = 43/145 (29%), Positives = 69/145 (47%), Gaps = 1/145 (0%)
 Frame = -1

Query: 691 GAIGMEIAKRLRPFGVKILATKRNWSSNTASCDLDGLVDKKGGPEEMYELAREADIVITC 512
           G IG E+A R++ FG+K +      S   A+        ++   EE++ L    D +   
Sbjct: 153 GRIGREVATRMQSFGMKTVGYDPIISPEVAA----SFGVQQLPLEEIWPLC---DFITVH 205

Query: 511 MTLNNESVGIVNHKFLSTLKKGSYLINIARGRLLDYTAVFNHLESGHLGGLGIDVAWTEP 332
             L   + G++N    +  KKG  ++N ARG ++D  A+   L+SG   G  +DV   EP
Sbjct: 206 TPLLPSTTGLLNDSTFAQCKKGVRVVNCARGGIVDEGALLRALQSGQCAGAALDVFTEEP 265

Query: 331 FDPED-PILKFPNVIITPHIAGITE 260
             P D  ++   NVI  PH+   T+
Sbjct: 266 --PRDRALVDHENVISCPHLGASTK 288

---

>SERA_MACFA (Q60HD7) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (3-PGDH)|
          Length = 532

 Score = 56.6 bits (135), Expect = 7e-08
 Identities = 45/146 (30%), Positives = 70/146 (47%), Gaps = 2/146 (1%)
 Frame = -1

Query: 691 GAIGMEIAKRLRPFGVKILATKRNWSSN-TASCDLDGLVDKKGGPEEMYELAREADIVIT 515
           G IG E+A R++ FG+K +      S   +AS  +  L       EE++ L    D +  
Sbjct: 153 GRIGREVATRMQSFGMKTIGYDPIISPEVSASFGVQQLP-----LEEIWPLC---DFITV 204

Query: 514 CMTLNNESVGIVNHKFLSTLKKGSYLINIARGRLLDYTAVFNHLESGHLGGLGIDVAWTE 335
              L   + G++N    +  KKG  ++N ARG ++D  A+   L+SG   G  +DV   E
Sbjct: 205 HTPLLPSTTGLLNDNTFAQCKKGVRVVNCARGGIVDEGALLRALQSGQCAGAALDVFTEE 264

Query: 334 PFDPED-PILKFPNVIITPHIAGITE 260
           P  P D  ++   NVI  PH+   T+
Sbjct: 265 P--PRDRALVDHENVISCPHLGASTK 288

---

>SERA_HUMAN (O43175) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (3-PGDH)|
          Length = 532

 Score = 56.6 bits (135), Expect = 7e-08
 Identities = 45/146 (30%), Positives = 70/146 (47%), Gaps = 2/146 (1%)
 Frame = -1

Query: 691 GAIGMEIAKRLRPFGVKILATKRNWSSN-TASCDLDGLVDKKGGPEEMYELAREADIVIT 515
           G IG E+A R++ FG+K +      S   +AS  +  L       EE++ L    D +  
Sbjct: 153 GRIGREVATRMQSFGMKTIGYDPIISPEVSASFGVQQLP-----LEEIWPLC---DFITV 204

Query: 514 CMTLNNESVGIVNHKFLSTLKKGSYLINIARGRLLDYTAVFNHLESGHLGGLGIDVAWTE 335
              L   + G++N    +  KKG  ++N ARG ++D  A+   L+SG   G  +DV   E
Sbjct: 205 HTPLLPSTTGLLNDNTFAQCKKGVRVVNCARGGIVDEGALLRALQSGQCAGAALDVFTEE 264

Query: 334 PFDPED-PILKFPNVIITPHIAGITE 260
           P  P D  ++   NVI  PH+   T+
Sbjct: 265 P--PRDRALVDHENVISCPHLGASTK 288

---

>LDHD_PEDAC (Q59642) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific|
           D-2-hydroxyacid dehydrogenase)
          Length = 331

 Score = 56.6 bits (135), Expect = 7e-08
 Identities = 45/171 (26%), Positives = 81/171 (47%), Gaps = 15/171 (8%)
 Frame = -1

Query: 691 GAIGMEIAKRLRPFGVKILATK--RNWSSNTASCDLDGLVDKKGGPEEMYELAREADIVI 518
           G IG       +PFG K++A    RN +       +D L       EE+Y+   +A+++ 
Sbjct: 153 GRIGRAAIDIFKPFGAKVIAYDVFRNPALEKEGMYVDTL-------EELYQ---QANVIT 202

Query: 517 TCMTLNNESVGIVNHKFLSTLKKGSYLINIARGRLLDYTAVFNHLESGHLGGLGIDVAWT 338
             +    ++  +++ K    ++ G++++N ARG L+D  A+   L+SG + G  +D    
Sbjct: 203 LHVPALKDNYHMLDEKAFGQMQDGTFILNFARGTLVDTPALLKALDSGKVAGAALDTYEN 262

Query: 337 EP--FDP-------EDPI----LKFPNVIITPHIAGITEYSYRTMAKVVGD 224
           E   FD        +DP+    +   NV+ITPH A  T  + + M ++  D
Sbjct: 263 EVGIFDVDHGDQPIDDPVFNDLMSRRNVMITPHAAFYTRPAVKNMVQIALD 313

---

>LDHD_STRA3 (Q8E6A9) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific|
           D-2-hydroxyacid dehydrogenase)
          Length = 330

 Score = 56.6 bits (135), Expect = 7e-08
 Identities = 45/165 (27%), Positives = 75/165 (45%), Gaps = 13/165 (7%)
 Frame = -1

Query: 691 GAIGMEIAKRLRPFGVKILATKRNWSSNTASCDLDGLVDKKGGPEEMYELAREADIVITC 512
           G IG+  AK  + FG +++      +        DG+++     EE  E   +AD+V   
Sbjct: 154 GRIGLATAKIFKGFGCRVIGYDIYHNPMA-----DGILEYVNSVEEAVE---KADLVSLH 205

Query: 511 MTLNNESVGIVNHKFLSTLKKGSYLINIARGRLLDYTAVFNHLESGHLGGLGIDVAWTE- 335
           M    E+  + N       KKG+ L+N+ARG L++   +   L+ G L G GID    E 
Sbjct: 206 MPPTAENTHLFNLDMFKQFKKGAILMNMARGALVETKDLLEALDQGLLEGAGIDTYEFEG 265

Query: 334 PFDPED------------PILKFPNVIITPHIAGITEYSYRTMAK 236
           P+ P++             ++  P VI TPH A  T+ + + + +
Sbjct: 266 PYIPKNCQGQDISDKDFLRLINHPKVIYTPHAAYYTDEAVKNLVE 310

---

>FDH1_YEAST (Q08911) Formate dehydrogenase 1 (EC 1.2.1.2) (NAD-dependent|
           formate dehydrogenase 1)
          Length = 376

 Score = 55.8 bits (133), Expect = 1e-07
 Identities = 47/170 (27%), Positives = 78/170 (45%), Gaps = 13/170 (7%)
 Frame = -1

Query: 691 GAIGMEIAKRLRPFGVKILA--------TKRNWSSNTASCDLDGLVDKKGGPEEMYELAR 536
           G IG  + +RL  F  K L          +     N AS   +G  D     E++ ++  
Sbjct: 175 GRIGYRVLERLVAFNPKKLLYYDYQELPAEAINRLNEASKLFNGRGDIVQRVEKLEDMVA 234

Query: 535 EADIVITCMTLNNESVGIVNHKFLSTLKKGSYLINIARGRLLDYTAVFNHLESGHLGGLG 356
           ++D+V     L+ +S G+ N K +S +K G+YL+N ARG +     V   ++SG L G G
Sbjct: 235 QSDVVTINCPLHKDSRGLFNKKLISHMKDGAYLVNTARGAICVAEDVAEAVKSGKLAGYG 294

Query: 355 IDVAWTEPFDPEDPILKFPNV-----IITPHIAGITEYSYRTMAKVVGDV 221
            DV   +P   + P     N       +T HI+G +  + +  A+ V ++
Sbjct: 295 GDVWDKQPAPKDHPWRTMDNKDHVGNAMTVHISGTSLDAQKRYAQGVKNI 344

---

>SERA_BOVIN (Q5EAD2) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (3-PGDH)|
          Length = 532

 Score = 55.8 bits (133), Expect = 1e-07
 Identities = 44/146 (30%), Positives = 70/146 (47%), Gaps = 2/146 (1%)
 Frame = -1

Query: 691 GAIGMEIAKRLRPFGVKILATKRNWSSN-TASCDLDGLVDKKGGPEEMYELAREADIVIT 515
           G IG E+A R++ FG+K +      S   +AS  +  L       E+++ L    D +  
Sbjct: 153 GRIGREVATRMQSFGMKTIGYDPIISPEVSASFGVQQLP-----LEQIWPLC---DFITV 204

Query: 514 CMTLNNESVGIVNHKFLSTLKKGSYLINIARGRLLDYTAVFNHLESGHLGGLGIDVAWTE 335
              L   + G++N    +  KKG  ++N ARG ++D  A+   L+SG   G  +DV   E
Sbjct: 205 HTPLLPSTTGLLNDSTFAQCKKGVCVVNCARGGIVDEGALLRALQSGQCAGAALDVFTEE 264

Query: 334 PFDPED-PILKFPNVIITPHIAGITE 260
           P  P D  ++   NVI  PH+   T+
Sbjct: 265 P--PRDRALVNHENVISCPHLGASTK 288

---

>FDH_PICAN (P33677) Formate dehydrogenase (EC 1.2.1.2) (NAD-dependent formate|
           dehydrogenase) (FDH)
          Length = 361

 Score = 55.8 bits (133), Expect = 1e-07
 Identities = 47/149 (31%), Positives = 68/149 (45%), Gaps = 8/149 (5%)
 Frame = -1

Query: 691 GAIGMEIAKRLRPFGVKILATKRNWSSNTASCDLDGLVDKKGGPEEMY---ELAREADIV 521
           G IG  + +RL  F  K L      S       L    ++K G   ++   EL  +ADIV
Sbjct: 172 GRIGYRVLERLVAFNPKELLYYDYQS-------LSKEAEEKVGARRVHDIKELVAQADIV 224

Query: 520 ITCMTLNNESVGIVNHKFLSTLKKGSYLINIARGRLLDYTAVFNHLESGHLGGLGIDVAW 341
                L+  S G+VN + L   KKG++L+N ARG +     V   ++SG L G G DV +
Sbjct: 225 TINCPLHAGSKGLVNAELLKHFKKGAWLVNTARGAICVAEDVAAAVKSGQLRGYGGDVWF 284

Query: 340 TEPFDPEDPILKFPNV-----IITPHIAG 269
            +P   + P     N       +TPH +G
Sbjct: 285 PQPAPKDHPWRSMANKYGAGNAMTPHYSG 313

---

>YGT5_YEAST (P53100) Putative 2-hydroxyacid dehydrogenase YGL185C (EC 1.-.-.-)|
          Length = 379

 Score = 53.9 bits (128), Expect = 4e-07
 Identities = 44/175 (25%), Positives = 82/175 (46%), Gaps = 3/175 (1%)
 Frame = -1

Query: 691 GAIGMEIAKRLR-PFGVKILATKRNWSSNTASCDL--DGLVDKKGGPEEMYELAREADIV 521
           G+IG ++A +L+   G++I   KR+     +  +     L+D     E +Y    +   +
Sbjct: 206 GSIGKQVAYKLQYGLGMEIHYCKRSEDCTMSQNESWKFHLLD-----ETIYAKLYQFHAI 260

Query: 520 ITCMTLNNESVGIVNHKFLSTLKKGSYLINIARGRLLDYTAVFNHLESGHLGGLGIDVAW 341
           +  +    ++  ++N KFL     G  L+N+ RG++LD  AV + L +G +  LG+DV  
Sbjct: 261 VVTLPGTPQTEHLINRKFLEHCNPGLILVNLGRGKILDLRAVSDALVTGRINHLGLDVFN 320

Query: 340 TEPFDPEDPILKFPNVIITPHIAGITEYSYRTMAKVVGDVALKLHAGEPFNEIEF 176
            EP   E          ITPH+   T+  +    ++     L++ +GE  ++  F
Sbjct: 321 KEPEIDEKIRSSDRLTSITPHLGSATKDVFEQSCELALTRILRVVSGEAASDEHF 375

---

>YN14_YEAST (P53839) Putative 2-hydroxyacid dehydrogenase YNL274C (EC 1.-.-.-)|
          Length = 350

 Score = 53.9 bits (128), Expect = 4e-07
 Identities = 41/157 (26%), Positives = 73/157 (46%), Gaps = 3/157 (1%)
 Frame = -1

Query: 691 GAIGMEIAKRLRPFGVKILATKRNW---SSNTASCDLDGLVDKKGGPEEMYELAREADIV 521
           G IG  I +RL+PFG +           S     C+  G            E  + +DIV
Sbjct: 172 GRIGRCILERLKPFGFENFIYHNRHQLPSEEEHGCEYVGFE----------EFLKRSDIV 221

Query: 520 ITCMTLNNESVGIVNHKFLSTLKKGSYLINIARGRLLDYTAVFNHLESGHLGGLGIDVAW 341
              + LN+ +  ++N + +  +K G  ++N ARG ++D  A+ + L SG +   G+DV  
Sbjct: 222 SVNVPLNHNTHHLINAETIEKMKDGVVIVNTARGAVIDEQAMTDALRSGKIRSAGLDVFE 281

Query: 340 TEPFDPEDPILKFPNVIITPHIAGITEYSYRTMAKVV 230
            EP   ++ +L    V+  PH+   +  + + M ++V
Sbjct: 282 YEPKISKE-LLSMSQVLGLPHMGTHSVETRKKMEELV 317

---

>SERA_YEAST (P40054) D-3-phosphoglycerate dehydrogenase 1 (EC 1.1.1.95) (3-PGDH|
           1)
          Length = 469

 Score = 52.8 bits (125), Expect = 1e-06
 Identities = 34/137 (24%), Positives = 66/137 (48%), Gaps = 13/137 (9%)
 Frame = -1

Query: 547 ELAREADIVITCMTLNNESVGIVNHKFLSTLKKGSYLINIARGRLLDYTAVFNHLESGHL 368
           EL  ++D V   +    E+  +++    + +K G+Y+IN +RG ++D  ++   +++  +
Sbjct: 246 ELLNKSDFVTLHVPATPETEKMLSAPQFAAMKDGAYVINASRGTVVDIPSLIQAVKANKI 305

Query: 367 GGLGIDVAWTEP-------FDPE-----DPILKFPNVIITPHIAGITEYSYRTMAKVVGD 224
            G  +DV   EP       F+ E       ++  PN+I+TPHI G TE +  ++   V  
Sbjct: 306 AGAALDVYPHEPAKNGEGSFNDELNSWTSELVSLPNIILTPHIGGSTEEAQSSIGIEVAT 365

Query: 223 VALK-LHAGEPFNEIEF 176
              K ++ G     + F
Sbjct: 366 ALSKYINEGNSVGSVNF 382

---

>SER33_YEAST (P40510) D-3-phosphoglycerate dehydrogenase 2 (EC 1.1.1.95) (3-PGDH|
           2)
          Length = 469

 Score = 52.8 bits (125), Expect = 1e-06
 Identities = 34/137 (24%), Positives = 66/137 (48%), Gaps = 13/137 (9%)
 Frame = -1

Query: 547 ELAREADIVITCMTLNNESVGIVNHKFLSTLKKGSYLINIARGRLLDYTAVFNHLESGHL 368
           EL  ++D V   +    E+  +++    + +K G+Y+IN +RG ++D  ++   +++  +
Sbjct: 246 ELLNKSDFVTLHVPATPETEKMLSAPQFAAMKDGAYVINASRGTVVDIPSLIQAVKANKI 305

Query: 367 GGLGIDVAWTEP-------FDPE-----DPILKFPNVIITPHIAGITEYSYRTMAKVVGD 224
            G  +DV   EP       F+ E       ++  PN+I+TPHI G TE +  ++   V  
Sbjct: 306 AGAALDVYPHEPAKNGEGSFNDELNSWTSELVSLPNIILTPHIGGSTEEAQSSIGIEVAT 365

Query: 223 VALK-LHAGEPFNEIEF 176
              K ++ G     + F
Sbjct: 366 ALSKYINEGNSVGSVNF 382

---

>YP113_YEAST (Q02961) Putative 2-hydroxyacid dehydrogenase YPL113C (EC 1.-.-.-)|
          Length = 396

 Score = 52.4 bits (124), Expect = 1e-06
 Identities = 37/141 (26%), Positives = 62/141 (43%), Gaps = 1/141 (0%)
 Frame = -1

Query: 694 FGAIGMEIAKRL-RPFGVKILATKRNWSSNTASCDLDGLVDKKGGPEEMYELAREADIVI 518
           FG+IG  I   L + F + I   KR      +  D +            +   + AD++I
Sbjct: 225 FGSIGQNIGSNLHKVFNMSIEYYKRTGPVQKSLLDYNAKYHSDLDDPNTW---KNADLII 281

Query: 517 TCMTLNNESVGIVNHKFLSTLKKGSYLINIARGRLLDYTAVFNHLESGHLGGLGIDVAWT 338
             +     +  I+N K L+  K G  ++N+ RG  +D   + + LESG +   G+DV   
Sbjct: 282 LALPSTASTNNIINRKSLAWCKDGVRIVNVGRGTCIDEDVLLDALESGKVASCGLDVFKN 341

Query: 337 EPFDPEDPILKFPNVIITPHI 275
           E    +  +L+  +V   PHI
Sbjct: 342 EETRVKQELLRRWDVTALPHI 362

---

>LDHD_LEUMC (P51011) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific|
           D-2-hydroxyacid dehydrogenase)
          Length = 331

 Score = 52.4 bits (124), Expect = 1e-06
 Identities = 47/178 (26%), Positives = 75/178 (42%), Gaps = 13/178 (7%)
 Frame = -1

Query: 691 GAIGMEIAKRLRPFGVKILATKRNWSSNTASCDLDGLVDKKGGPEEMYELAREADIVITC 512
           G IG      L+ FG K++A  +      A    +GL       + + EL  +AD +   
Sbjct: 154 GHIGRVAINILKGFGAKVIAYDKY---PNAELQAEGLY-----VDTLDELYAQADAISLY 205

Query: 511 MTLNNESVGIVNHKFLSTLKKGSYLINIARGRLLDYTAVFNHLESGHLGGLGIDVAWTE- 335
           +    E+  ++N   ++ +K G  ++N ARG L+D  A+ + L SG +   G+DV   E 
Sbjct: 206 VPGVPENHHLINADAIAKMKDGVVIMNAARGNLMDIDAIIDGLNSGKISDFGMDVYENEV 265

Query: 334 ------------PFDPEDPILKFPNVIITPHIAGITEYSYRTMAKVVGDVALKLHAGE 197
                       P      ++   NV+ITPH A  T  +   M     D A+    GE
Sbjct: 266 ACSMKIGLVKNSPDAKIADLIARENVMITPHTAFYTTKAVLEMVHQSFDAAVAFAKGE 323

---

>FDH_EMENI (Q03134) Probable formate dehydrogenase (EC 1.2.1.2) (NAD-dependent|
           formate dehydrogenase) (FDH)
          Length = 377

 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 42/147 (28%), Positives = 67/147 (45%), Gaps = 20/147 (13%)
 Frame = -1

Query: 691 GAIGMEIAKRLRPFGVKILATKRNWSSNTASCDLDGLVDKKGGP---EEMYELAREADIV 521
           G IG  + +RL+PF  K L              L   V+K+ G    + + E+  + D+V
Sbjct: 169 GRIGERVLRRLKPFDCKELLYYDYQP-------LRPEVEKEIGARRVDSLEEMVSQCDVV 221

Query: 520 ITCMTLNNESVGIVNHKFLSTLK-----------------KGSYLINIARGRLLDYTAVF 392
                L+ ++ G+ N + +S +K                 KGS+L+N ARG ++    V 
Sbjct: 222 TINCPLHEKTRGLFNKELISKMKPGKSALLYLIIPMLMYHKGSWLVNTARGAIVVKEDVA 281

Query: 391 NHLESGHLGGLGIDVAWTEPFDPEDPI 311
             L+SGHL G G DV + +P   E P+
Sbjct: 282 EALKSGHLRGYGGDVWFPQPAPKEHPL 308

---

>LDHD_STAES (Q8CN22) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific|
           D-2-hydroxyacid dehydrogenase)
          Length = 330

 Score = 51.6 bits (122), Expect = 2e-06
 Identities = 32/121 (26%), Positives = 62/121 (51%), Gaps = 13/121 (10%)
 Frame = -1

Query: 559 EEMYELAREADIVITCMTLNNESVGIVNHKFLSTLKKGSYLINIARGRLLDYTAVFNHLE 380
           E + +  ++ADI+   +  N +S  + ++     +KKG+ L+N ARG +++   +   + 
Sbjct: 190 ETVEDAIKDADIISLHVPANKDSFHLFDNNMFKNVKKGAVLVNAARGAVINTPDLIEAVN 249

Query: 379 SGHLGGLGIDVAWTE----PFD-----PEDPIL----KFPNVIITPHIAGITEYSYRTMA 239
           +G L G  ID    E     FD      +DPIL    +  N+++TPHIA  ++ + + + 
Sbjct: 250 NGTLSGAAIDTYENEANYFTFDCSNQTIDDPILLDLIRNENILVTPHIAFFSDEAVQNLV 309

Query: 238 K 236
           +
Sbjct: 310 E 310

---

>LDHD_STAEQ (Q5HLA0) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific|
           D-2-hydroxyacid dehydrogenase)
          Length = 330

 Score = 51.6 bits (122), Expect = 2e-06
 Identities = 32/121 (26%), Positives = 62/121 (51%), Gaps = 13/121 (10%)
 Frame = -1

Query: 559 EEMYELAREADIVITCMTLNNESVGIVNHKFLSTLKKGSYLINIARGRLLDYTAVFNHLE 380
           E + +  ++ADI+   +  N +S  + ++     +KKG+ L+N ARG +++   +   + 
Sbjct: 190 ETVEDAIKDADIISLHVPANKDSFHLFDNNMFKNVKKGAVLVNAARGAVINTPDLIEAVN 249

Query: 379 SGHLGGLGIDVAWTE----PFD-----PEDPIL----KFPNVIITPHIAGITEYSYRTMA 239
           +G L G  ID    E     FD      +DPIL    +  N+++TPHIA  ++ + + + 
Sbjct: 250 NGTLSGAAIDTYENEANYFTFDCSNQTIDDPILLDLIRNENILVTPHIAFFSDEAVQNLV 309

Query: 238 K 236
           +
Sbjct: 310 E 310

---

>DHGY_HYPME (P36234) Glycerate dehydrogenase (EC 1.1.1.29) (NADH-dependent|
           hydroxypyruvate reductase) (HPR) (GDH) (Hydroxypyruvate
           dehydrogenase) (Glyoxylate reductase)
          Length = 321

 Score = 50.8 bits (120), Expect = 4e-06
 Identities = 47/169 (27%), Positives = 70/169 (41%), Gaps = 4/169 (2%)
 Frame = -1

Query: 694 FGAIGMEIAKRLRPFGVKI--LATKRNWSSNTAS--CDLDGLVDKKGGPEEMYELAREAD 527
           FG+IG  +AKR + F + I    T R  SS+ AS        +D      + + L   + 
Sbjct: 155 FGSIGQALAKRAQGFDMDIDYFDTHRASSSDEASYQATFHDSLDSLLSVSQFFSLNAPS- 213

Query: 526 IVITCMTLNNESVGIVNHKFLSTLKKGSYLINIARGRLLDYTAVFNHLESGHLGGLGIDV 347
                     E+    N   + +L +G+ ++N ARG L+D   V   LE+G L   G DV
Sbjct: 214 --------TPETRYFFNKATIKSLPQGAIVVNTARGDLVDNELVVAALEAGRLAYAGFDV 265

Query: 346 AWTEPFDPEDPILKFPNVIITPHIAGITEYSYRTMAKVVGDVALKLHAG 200
              EP +  +     PN  + PHI      +   MA    D+   L  G
Sbjct: 266 FAGEP-NINEGYYDLPNTFLFPHIGSAATQAREDMAHQANDLIDALFGG 313

---

>SERA_PONPY (Q5R7M2) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (3-PGDH)|
          Length = 532

 Score = 50.8 bits (120), Expect = 4e-06
 Identities = 42/145 (28%), Positives = 67/145 (46%), Gaps = 1/145 (0%)
 Frame = -1

Query: 691 GAIGMEIAKRLRPFGVKILATKRNWSSN-TASCDLDGLVDKKGGPEEMYELAREADIVIT 515
           G IG E+A R++  G+K +      S   +AS  +  L       EE++ L    D +  
Sbjct: 153 GRIGREVAIRMQSLGMKTIGYDPIISPEVSASFGVQQLP-----LEEIWPLC---DFITV 204

Query: 514 CMTLNNESVGIVNHKFLSTLKKGSYLINIARGRLLDYTAVFNHLESGHLGGLGIDVAWTE 335
              L   + G++N    +  KKG  ++N ARG ++D  A+   L+SG   G  +DV   E
Sbjct: 205 HTPLLPSTTGLLNDNTFAQCKKGVRVVNCARGGIVDEGALLRALQSGQCAGAALDVFTEE 264

Query: 334 PFDPEDPILKFPNVIITPHIAGITE 260
           P      ++   NVI  PH+   T+
Sbjct: 265 P-PRGRALVDHENVISCPHLGASTK 288

---

>DDH_HAEIN (P44501) 2-hydroxyacid dehydrogenase homolog (EC 1.1.1.-)|
          Length = 331

 Score = 50.8 bits (120), Expect = 4e-06
 Identities = 47/179 (26%), Positives = 85/179 (47%), Gaps = 14/179 (7%)
 Frame = -1

Query: 691 GAIGMEIAKRLRPFGVKILATKRNWSSNTASCDLDGLVDKKGGPE-EMYELAREADIVIT 515
           G IG+ + + L+ FG+ ILA     +          +V++ GG   E+ EL  ++ ++  
Sbjct: 153 GKIGIAVMRILKGFGMNILAYDPFKNP---------VVEELGGQYVELDELYAKSHVITL 203

Query: 514 CMTLNNESVGIVNHKFLSTLKKGSYLINIARGRLLDYTAVFNHLESGHLGGLGIDVAWTE 335
                 E+  ++N +  + +K G  ++N +RG L+D  A  + L+   +G LG+DV   E
Sbjct: 204 HCPATPENYHLLNCEAFAKMKDGVMIVNTSRGSLIDTQAAIDALKQRKIGALGMDVYENE 263

Query: 334 P---FDP------EDPILK----FPNVIITPHIAGITEYSYRTMAKVVGDVALKLHAGE 197
               F+       +D I +      NV++T H A +TE +   +A V      KL +G+
Sbjct: 264 RDLFFEDKSNEVIQDDIFRRLSSCHNVLLTGHQAFLTEEALTNIADVTLSNIYKLKSGK 322

---

>PDXB_YERPS (Q668W7) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)|
          Length = 375

 Score = 50.1 bits (118), Expect = 6e-06
 Identities = 54/174 (31%), Positives = 78/174 (44%), Gaps = 8/174 (4%)
 Frame = -1

Query: 691 GAIGMEIAKRLRPFGVKILAT---KRNWSSNTASCDLDGLVDKKGGPEEMYELAREADIV 521
           G +G  +  RL+  GV+ L     + +   N A   L+ LV             READ++
Sbjct: 125 GNVGSRLNARLQALGVRTLLCDPPRADRGDNEAFWPLEKLV-------------READVL 171

Query: 520 ITCMTLNN----ESVGIVNHKFLSTLKKGSYLINIARGRLLDYTAVFNHLESGHLGGLGI 353
                LN     +S+ + + + L+ L  G  LIN  RG ++D  A+   LE G    + +
Sbjct: 172 TFHTPLNKTGAYQSLHMADDELLAALPDGRILINACRGAVVDNAALLRALEKGKKLSVVL 231

Query: 352 DVAWTEPFDPEDPILKFPNVIITPHIAGIT-EYSYRTMAKVVGDVALKLHAGEP 194
           DV   EP D   P+L   + I TPHIAG T E   R   +V    A   H G+P
Sbjct: 232 DVWEPEP-DLSLPLLARVD-IGTPHIAGYTLEGKARGTTQVF--EAFSQHLGQP 281

---

>PDXB_YERPE (Q8D0U3) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)|
          Length = 375

 Score = 50.1 bits (118), Expect = 6e-06
 Identities = 54/174 (31%), Positives = 78/174 (44%), Gaps = 8/174 (4%)
 Frame = -1

Query: 691 GAIGMEIAKRLRPFGVKILAT---KRNWSSNTASCDLDGLVDKKGGPEEMYELAREADIV 521
           G +G  +  RL+  GV+ L     + +   N A   L+ LV             READ++
Sbjct: 125 GNVGSRLNARLQALGVRTLLCDPPRADRGDNEAFWPLEKLV-------------READVL 171

Query: 520 ITCMTLNN----ESVGIVNHKFLSTLKKGSYLINIARGRLLDYTAVFNHLESGHLGGLGI 353
                LN     +S+ + + + L+ L  G  LIN  RG ++D  A+   LE G    + +
Sbjct: 172 TFHTPLNKTGAYQSLHMADDELLAALPDGRILINACRGAVVDNAALLRALEKGKKLSVVL 231

Query: 352 DVAWTEPFDPEDPILKFPNVIITPHIAGIT-EYSYRTMAKVVGDVALKLHAGEP 194
           DV   EP D   P+L   + I TPHIAG T E   R   +V    A   H G+P
Sbjct: 232 DVWEPEP-DLSLPLLARVD-IGTPHIAGYTLEGKARGTTQVF--EAFSQHLGQP 281

---

>LDHD_LACPL (Q88VJ2) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH)|
          Length = 332

 Score = 50.1 bits (118), Expect = 6e-06
 Identities = 43/168 (25%), Positives = 74/168 (44%), Gaps = 15/168 (8%)
 Frame = -1

Query: 691 GAIGMEIAKRLRPFGVKILA--TKRNWSSNTASCDLDGLVDKKGGPEEMYELAREADIVI 518
           G IG       + FG K++     RN     A  + +G+       + + EL  +AD++ 
Sbjct: 154 GRIGRAAIDIFKGFGAKVIGYDVYRN-----AELEKEGMY-----VDTLDELYAQADVIT 203

Query: 517 TCMTLNNESVGIVNHKFLSTLKKGSYLINIARGRLLDYTAVFNHLESGHLGGLGIDV--A 344
             +    ++  ++N    S +K G+Y++N ARG L+D   +   L+SG + G  +D    
Sbjct: 204 LHVPALKDNYHMLNADAFSKMKDGAYILNFARGTLIDSEDLIKALDSGKVAGAALDTYEY 263

Query: 343 WTEPFDPE-----------DPILKFPNVIITPHIAGITEYSYRTMAKV 233
            T+ F+ +             +    NV+ITPH A  TE +   M  V
Sbjct: 264 ETKIFNKDLEGQTIDDKVFMNLFNRDNVLITPHTAFYTETAVHNMVHV 311

---

>YEAA_SCHPO (O14075) Putative 2-hydroxyacid dehydrogenase UNK4.10 (EC 1.-.-.-)|
          Length = 334

 Score = 49.7 bits (117), Expect = 8e-06
 Identities = 38/142 (26%), Positives = 66/142 (46%), Gaps = 3/142 (2%)
 Frame = -1

Query: 691 GAIGMEIAKRLRPFGVKILATKRNWSSNTASCDLDGLVDKKGGPEEMY---ELAREADIV 521
           G IG  +AKR R F +KI+   R             L +++    E     +L  ++D++
Sbjct: 165 GGIGKTMAKRARAFDMKIVYHNRT-----------PLPEEEAEGAEFVSFDDLLAKSDVL 213

Query: 520 ITCMTLNNESVGIVNHKFLSTLKKGSYLINIARGRLLDYTAVFNHLESGHLGGLGIDVAW 341
              + LN  +  I+       +K+G  ++N ARG ++D  A+   L+ G +   G+DV  
Sbjct: 214 SLNLPLNAHTRHIIGKPEFQKMKRGIVIVNTARGAVMDEAALVEALDEGIVYSAGLDVFE 273

Query: 340 TEPFDPEDPILKFPNVIITPHI 275
            EP      +L+   VI+ PH+
Sbjct: 274 EEP-KIHPGLLENEKVILLPHL 294

---

>LDHD_STAAR (Q6GDS2) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific|
           D-2-hydroxyacid dehydrogenase)
          Length = 330

 Score = 49.7 bits (117), Expect = 8e-06
 Identities = 43/166 (25%), Positives = 74/166 (44%), Gaps = 14/166 (8%)
 Frame = -1

Query: 691 GAIGMEIAKRLRPFGVKILATKRNWSSNTASCDLDGLVDKKGGPEEMYELAREADIVITC 512
           G IG   AK    FG  I A     +      DLD L  K    + + E  ++ADI+   
Sbjct: 155 GRIGAATAKIYAGFGATITAYDAYPNK-----DLDFLTYK----DSVKEAIKDADIISLH 205

Query: 511 MTLNNESVGIVNHKFLSTLKKGSYLINIARGRLLDYTAVFNHLESGHLGGLGIDV----- 347
           +  N ES  + +      +KKG+ L+N ARG +++   + + +  G L G  ID      
Sbjct: 206 VPANKESYHLFDKTMFDHVKKGAILVNAARGAVINTPDLIDAVNDGTLLGAAIDTYENEA 265

Query: 346 -----AWTEPFDPED----PILKFPNVIITPHIAGITEYSYRTMAK 236
                 WT   D +D     +++   +++TPHIA  ++ + + + +
Sbjct: 266 AYFTNDWTNK-DIDDKTLLELIEHERILVTPHIAFFSDEAVQNLVE 310

---

>YMP5_STRCO (P43169) Hypothetical protein in mprR 3'region (EC 1.-.-.-) (ORF5)|
           (Fragment)
          Length = 278

 Score = 49.3 bits (116), Expect = 1e-05
 Identities = 40/143 (27%), Positives = 61/143 (42%)
 Frame = -1

Query: 691 GAIGMEIAKRLRPFGVKILATKRNWSSNTASCDLDGLVDKKGGPEEMYELAREADIVITC 512
           G IG  +A RL   G+  +   R      A     G  D++    E       A  V+  
Sbjct: 111 GHIGTAVASRLGAAGLHTVGVGR------AEHAPGGPFDERITAGEDGPWLGRARFVVDA 164

Query: 511 MTLNNESVGIVNHKFLSTLKKGSYLINIARGRLLDYTAVFNHLESGHLGGLGIDVAWTEP 332
           + L + +        LS L+ G+  +N+ RG  +   A+   L +GH+ G  +DV   EP
Sbjct: 165 LPLTDATRDFFADARLSALR-GATFLNVGRGATVSLPALGRALAAGHVRGAVLDVLTDEP 223

Query: 331 FDPEDPILKFPNVIITPHIAGIT 263
             P  P+ + P   +T H AGIT
Sbjct: 224 PAPGHPVWELPRTTLTSHSAGIT 246

---

>LDHD_STAAW (Q8NUT2) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific|
           D-2-hydroxyacid dehydrogenase)
          Length = 330

 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 43/166 (25%), Positives = 73/166 (43%), Gaps = 14/166 (8%)
 Frame = -1

Query: 691 GAIGMEIAKRLRPFGVKILATKRNWSSNTASCDLDGLVDKKGGPEEMYELAREADIVITC 512
           G IG   AK    FG  I A     +      DLD L  K    + + E  ++ADI+   
Sbjct: 155 GRIGAATAKIYAGFGATITAYDAYPNK-----DLDFLTYK----DSVKEAIKDADIISLH 205

Query: 511 MTLNNESVGIVNHKFLSTLKKGSYLINIARGRLLDYTAVFNHLESGHLGGLGIDV----- 347
           +  N ES  + +      +KKG+ L+N ARG +++   +   +  G L G  ID      
Sbjct: 206 VPANKESYHLFDKAMFDHVKKGAILVNAARGAVINTPDLIAAVNDGTLLGAAIDTYENEA 265

Query: 346 -----AWTEPFDPED----PILKFPNVIITPHIAGITEYSYRTMAK 236
                 WT   D +D     +++   +++TPHIA  ++ + + + +
Sbjct: 266 AYFTNDWTNK-DIDDKTLLELIEHERILVTPHIAFFSDEAVQNLVE 310

---

>LDHD_STAAU (P72357) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific|
           D-2-hydroxyacid dehydrogenase)
          Length = 330

 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 43/166 (25%), Positives = 73/166 (43%), Gaps = 14/166 (8%)
 Frame = -1

Query: 691 GAIGMEIAKRLRPFGVKILATKRNWSSNTASCDLDGLVDKKGGPEEMYELAREADIVITC 512
           G IG   AK    FG  I A     +      DLD L  K    + + E  ++ADI+   
Sbjct: 155 GRIGAATAKIYAGFGATITAYDAYPNK-----DLDFLTYK----DSVKEAIKDADIISLH 205

Query: 511 MTLNNESVGIVNHKFLSTLKKGSYLINIARGRLLDYTAVFNHLESGHLGGLGIDV----- 347
           +  N ES  + +      +KKG+ L+N ARG +++   +   +  G L G  ID      
Sbjct: 206 VPANKESYHLFDKAMFDHVKKGAILVNAARGAVINTPDLIAAVNDGTLLGAAIDTYENEA 265

Query: 346 -----AWTEPFDPED----PILKFPNVIITPHIAGITEYSYRTMAK 236
                 WT   D +D     +++   +++TPHIA  ++ + + + +
Sbjct: 266 AYFTNDWTNK-DIDDKTLLELIEHERILVTPHIAFFSDEAVQNLVE 310

---

>LDHD_STAAS (Q6G6F1) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific|
           D-2-hydroxyacid dehydrogenase)
          Length = 330

 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 43/166 (25%), Positives = 73/166 (43%), Gaps = 14/166 (8%)
 Frame = -1

Query: 691 GAIGMEIAKRLRPFGVKILATKRNWSSNTASCDLDGLVDKKGGPEEMYELAREADIVITC 512
           G IG   AK    FG  I A     +      DLD L  K    + + E  ++ADI+   
Sbjct: 155 GRIGAATAKIYAGFGATITAYDAYPNK-----DLDFLTYK----DSVKEAIKDADIISLH 205

Query: 511 MTLNNESVGIVNHKFLSTLKKGSYLINIARGRLLDYTAVFNHLESGHLGGLGIDV----- 347
           +  N ES  + +      +KKG+ L+N ARG +++   +   +  G L G  ID      
Sbjct: 206 VPANKESYHLFDKAMFDHVKKGAILVNAARGAVINTPDLIAAVNDGTLLGAAIDTYENEA 265

Query: 346 -----AWTEPFDPED----PILKFPNVIITPHIAGITEYSYRTMAK 236
                 WT   D +D     +++   +++TPHIA  ++ + + + +
Sbjct: 266 AYFTNDWTNK-DIDDKTLLELIEHERILVTPHIAFFSDEAVQNLVE 310

---

>LDHD_STAAN (P99116) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific|
           D-2-hydroxyacid dehydrogenase)
          Length = 330

 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 43/166 (25%), Positives = 73/166 (43%), Gaps = 14/166 (8%)
 Frame = -1

Query: 691 GAIGMEIAKRLRPFGVKILATKRNWSSNTASCDLDGLVDKKGGPEEMYELAREADIVITC 512
           G IG   AK    FG  I A     +      DLD L  K    + + E  ++ADI+   
Sbjct: 155 GRIGAATAKIYAGFGATITAYDAYPNK-----DLDFLTYK----DSVKEAIKDADIISLH 205

Query: 511 MTLNNESVGIVNHKFLSTLKKGSYLINIARGRLLDYTAVFNHLESGHLGGLGIDV----- 347
           +  N ES  + +      +KKG+ L+N ARG +++   +   +  G L G  ID      
Sbjct: 206 VPANKESYHLFDKAMFDHVKKGAILVNAARGAVINTPDLIAAVNDGTLLGAAIDTYENEA 265

Query: 346 -----AWTEPFDPED----PILKFPNVIITPHIAGITEYSYRTMAK 236
                 WT   D +D     +++   +++TPHIA  ++ + + + +
Sbjct: 266 AYFTNDWTNK-DIDDKTLLELIEHERILVTPHIAFFSDEAVQNLVE 310

---

>LDHD_STAAM (P63940) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific|
           D-2-hydroxyacid dehydrogenase)
          Length = 330

 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 43/166 (25%), Positives = 73/166 (43%), Gaps = 14/166 (8%)
 Frame = -1

Query: 691 GAIGMEIAKRLRPFGVKILATKRNWSSNTASCDLDGLVDKKGGPEEMYELAREADIVITC 512
           G IG   AK    FG  I A     +      DLD L  K    + + E  ++ADI+   
Sbjct: 155 GRIGAATAKIYAGFGATITAYDAYPNK-----DLDFLTYK----DSVKEAIKDADIISLH 205

Query: 511 MTLNNESVGIVNHKFLSTLKKGSYLINIARGRLLDYTAVFNHLESGHLGGLGIDV----- 347
           +  N ES  + +      +KKG+ L+N ARG +++   +   +  G L G  ID      
Sbjct: 206 VPANKESYHLFDKAMFDHVKKGAILVNAARGAVINTPDLIAAVNDGTLLGAAIDTYENEA 265

Query: 346 -----AWTEPFDPED----PILKFPNVIITPHIAGITEYSYRTMAK 236
                 WT   D +D     +++   +++TPHIA  ++ + + + +
Sbjct: 266 AYFTNDWTNK-DIDDKTLLELIEHERILVTPHIAFFSDEAVQNLVE 310

---

>LDHD_STAAC (Q5HD29) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific|
           D-2-hydroxyacid dehydrogenase)
          Length = 330

 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 43/166 (25%), Positives = 73/166 (43%), Gaps = 14/166 (8%)
 Frame = -1

Query: 691 GAIGMEIAKRLRPFGVKILATKRNWSSNTASCDLDGLVDKKGGPEEMYELAREADIVITC 512
           G IG   AK    FG  I A     +      DLD L  K    + + E  ++ADI+   
Sbjct: 155 GRIGAATAKIYAGFGATITAYDAYPNK-----DLDFLTYK----DSVKEAIKDADIISLH 205

Query: 511 MTLNNESVGIVNHKFLSTLKKGSYLINIARGRLLDYTAVFNHLESGHLGGLGIDV----- 347
           +  N ES  + +      +KKG+ L+N ARG +++   +   +  G L G  ID      
Sbjct: 206 VPANKESYHLFDKAMFDHVKKGAILVNAARGAVINTPDLIAAVNDGTLLGAAIDTYENEA 265

Query: 346 -----AWTEPFDPED----PILKFPNVIITPHIAGITEYSYRTMAK 236
                 WT   D +D     +++   +++TPHIA  ++ + + + +
Sbjct: 266 AYFTNDWTNK-DIDDKTLLELIEHERILVTPHIAFFSDEAVQNLVE 310

---

>PDXB_PSEAE (Q9I3W9) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)|
          Length = 380

 Score = 47.8 bits (112), Expect = 3e-05
 Identities = 44/146 (30%), Positives = 64/146 (43%), Gaps = 5/146 (3%)
 Frame = -1

Query: 691 GAIGMEIAKRLRPFGVKILATKRNWSSNTASCDLDGLVDKKGGPEEMYE-LAREADIVIT 515
           G +G  + + LR  G K+L            CD      +  G     E L  EAD++  
Sbjct: 125 GQVGGRLVEVLRGLGWKVLV-----------CDPPRQAREPDGEFVSLERLLAEADVISL 173

Query: 514 CMTLNNESVGIVNHKF----LSTLKKGSYLINIARGRLLDYTAVFNHLESGHLGGLGIDV 347
              LN +      H      L+ L+ G++L+N +RG ++D  A+   LE G    + +DV
Sbjct: 174 HTPLNRDGEHPTRHLLDEPRLAALRPGTWLVNASRGAVVDNQALRRLLEGGADLEVALDV 233

Query: 346 AWTEPFDPEDPILKFPNVIITPHIAG 269
              EP    DP L    +I TPHIAG
Sbjct: 234 WEGEP--QADPELAARCLIATPHIAG 257

---

>PDXB_ECO57 (Q8XCR0) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)|
          Length = 378

 Score = 47.4 bits (111), Expect = 4e-05
 Identities = 43/147 (29%), Positives = 65/147 (44%), Gaps = 4/147 (2%)
 Frame = -1

Query: 691 GAIGMEIAKRLRPFGVKILATKRNWSSNTASCDLDGLVDKKGGPEEMYELAREADIVITC 512
           G +G  +  RL   G+K L          A C        +G    + EL + ADI+   
Sbjct: 125 GNVGRRLQARLEALGIKTLLC----DPPRADCG------DEGDFRSLDELVQRADILTFH 174

Query: 511 MTLNNE----SVGIVNHKFLSTLKKGSYLINIARGRLLDYTAVFNHLESGHLGGLGIDVA 344
             L  +    ++ + + K + +LK G+ LIN  RG ++D TA+   L  G    + +DV 
Sbjct: 175 TPLFKDGPYKTLHLADEKLIRSLKPGAILINACRGAVVDNTALLTCLNEGQKLSVVLDVW 234

Query: 343 WTEPFDPEDPILKFPNVIITPHIAGIT 263
             EP    + + K    I TPHIAG T
Sbjct: 235 EGEPELNVELLTKVD--IGTPHIAGYT 259

---

>LDHD_LACPE (P26298) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific|
           D-2-hydroxyacid dehydrogenase)
          Length = 332

 Score = 47.0 bits (110), Expect = 5e-05
 Identities = 43/169 (25%), Positives = 75/169 (44%), Gaps = 16/169 (9%)
 Frame = -1

Query: 691 GAIGMEIAKRLRPFGVKILA--TKRNWSSNTASCDLDGLVDKKGGPEEMYELAREADIVI 518
           G IG       + FG K++     RN     A  + +G+       + + EL  +AD++ 
Sbjct: 154 GRIGRAAIDIFKGFGAKVIGYDVYRN-----AELEKEGMY-----VDTLDELYAQADVIT 203

Query: 517 TCMTLNNESVGIVNHKFLSTLKKGSYLINIARGRLLDYTAVFNHLESGHLGGLGIDVAW- 341
             +    ++  ++N    S +K G+Y++N ARG L+D   +   L+SG + G  + V + 
Sbjct: 204 LHVPALKDNYHMLNADAFSKMKDGAYILNFARGTLIDSEDLIKALDSGKVAGAAL-VTYE 262

Query: 340 --TEPFDPE-----------DPILKFPNVIITPHIAGITEYSYRTMAKV 233
             T+ F+ +             +    NV+ITPH A  TE +   M  V
Sbjct: 263 YETKIFNKDLEGQTIDDKVFMNLFNRDNVLITPHTAFYTETAVHNMVHV 311

---

>PDXB_PHOLL (Q7N2B2) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)|
          Length = 375

 Score = 46.6 bits (109), Expect = 7e-05
 Identities = 46/149 (30%), Positives = 68/149 (45%), Gaps = 6/149 (4%)
 Frame = -1

Query: 691 GAIGMEIAKRLRPFGVKILATKRNWSSNTASCDLDGLVDKKGGPE--EMYELAREADIVI 518
           G +G  +A+RL   G++ L            CD     D+    E   + +L +EADI+ 
Sbjct: 125 GNVGSRLAERLAVLGIRTLL-----------CD-PPRADRGDAGEFWSLEKLVKEADILT 172

Query: 517 TCMTLNNESVGIVNH----KFLSTLKKGSYLINIARGRLLDYTAVFNHLESGHLGGLGID 350
               LN       +H    + LS L     LIN +RG ++D  A+   L+ G    + +D
Sbjct: 173 FHTPLNKSGPYKTHHLVDVELLSVLPDNRILINASRGEVIDNQALLTALKCGKKLRVVLD 232

Query: 349 VAWTEPFDPEDPILKFPNVIITPHIAGIT 263
           V   EP D   P+L+  + I TPHIAG T
Sbjct: 233 VWEPEP-DLSLPLLELVD-IGTPHIAGYT 259

---

>LDHD_ECOLI (P52643) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH)|
           (Fermentative lactate dehydrogenase)
          Length = 329

 Score = 46.6 bits (109), Expect = 7e-05
 Identities = 29/115 (25%), Positives = 57/115 (49%)
 Frame = -1

Query: 691 GAIGMEIAKRLRPFGVKILATKRNWSSNTASCDLDGLVDKKGGPEEMYELAREADIVITC 512
           G IG+ + + L+ FG+++LA     S+      ++ +        ++  L  E+D++   
Sbjct: 153 GKIGVAMLRILKGFGMRLLAFDPYPSAAALELGVEYV--------DLPTLFSESDVISLH 204

Query: 511 MTLNNESVGIVNHKFLSTLKKGSYLINIARGRLLDYTAVFNHLESGHLGGLGIDV 347
             L  E+  ++N      +K G  ++N +RG L+D  A    L++  +G LG+DV
Sbjct: 205 CPLTPENYHLLNEAAFEQMKNGVMIVNTSRGALIDSQAAIEALKNQKIGSLGMDV 259

---

>PDXB_SHIFL (Q83QR1) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)|
          Length = 378

 Score = 46.2 bits (108), Expect = 9e-05
 Identities = 44/149 (29%), Positives = 67/149 (44%), Gaps = 6/149 (4%)
 Frame = -1

Query: 691 GAIGMEIAKRLRPFGVKILATKRNWSSNTASCDLDGLVDK--KGGPEEMYELAREADIVI 518
           G +G  +  RL   G+K L            CD     D+  +G    + EL + ADI+ 
Sbjct: 125 GNVGRRLQARLEALGIKTLL-----------CD-PPRADRGDEGDFRSLDELVQRADILT 172

Query: 517 TCMTLNNE----SVGIVNHKFLSTLKKGSYLINIARGRLLDYTAVFNHLESGHLGGLGID 350
               L  +    ++ + + K + +LK G+ LIN  RG ++D TA+   L  G    + +D
Sbjct: 173 FHTPLFKDGPYKTLHLADEKLIRSLKPGAILINACRGAVVDNTALLTCLNEGQKLSVVLD 232

Query: 349 VAWTEPFDPEDPILKFPNVIITPHIAGIT 263
           V   EP    + + K    I TPHIAG T
Sbjct: 233 VWEGEPELNVELLTKVD--IGTPHIAGYT 259

---

>PDXB_ECOL6 (Q8FFH2) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)|
          Length = 378

 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 44/149 (29%), Positives = 67/149 (44%), Gaps = 6/149 (4%)
 Frame = -1

Query: 691 GAIGMEIAKRLRPFGVKILATKRNWSSNTASCDLDGLVDK--KGGPEEMYELAREADIVI 518
           G +G  +  RL   G+K L            CD     D+  +G    + EL + ADI+ 
Sbjct: 125 GNVGRRLQARLEALGIKTLL-----------CD-PPRADRGDEGDFRSLDELVQHADILT 172

Query: 517 TCMTLNNE----SVGIVNHKFLSTLKKGSYLINIARGRLLDYTAVFNHLESGHLGGLGID 350
               L  +    ++ + + K + +LK G+ LIN  RG ++D TA+   L  G    + +D
Sbjct: 173 FHTPLFKDGPYKTLHLADEKLIRSLKPGAILINACRGAVVDNTALLTCLNEGQKLSVVLD 232

Query: 349 VAWTEPFDPEDPILKFPNVIITPHIAGIT 263
           V   EP    + + K    I TPHIAG T
Sbjct: 233 VWEGEPELNVELLKKVD--IGTPHIAGYT 259

---

>PDXB_ECOLI (P05459) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)|
          Length = 378

 Score = 42.7 bits (99), Expect = 0.001
 Identities = 43/149 (28%), Positives = 66/149 (44%), Gaps = 6/149 (4%)
 Frame = -1

Query: 691 GAIGMEIAKRLRPFGVKILATKRNWSSNTASCDLDGLVDK--KGGPEEMYELAREADIVI 518
           G +G  +  RL   G+K L            CD     D+  +G    + EL + ADI+ 
Sbjct: 125 GNVGRRLQARLEALGIKTLL-----------CD-PPRADRGDEGDFRSLDELVQRADILT 172

Query: 517 TCMTLNNE----SVGIVNHKFLSTLKKGSYLINIARGRLLDYTAVFNHLESGHLGGLGID 350
               L  +    ++ + + K + +LK G+ LIN  RG ++D TA+   L  G    + +D
Sbjct: 173 FHTPLFKDGPYKTLHLADEKLIRSLKPGAILINACRGAVVDNTALLTCLNEGQKLSVVLD 232

Query: 349 VAWTEPFDPEDPILKFPNVIITPHIAGIT 263
           V   EP    + + K    I T HIAG T
Sbjct: 233 VWEGEPELNVELLKKVD--IGTSHIAGYT 259

---

>PDXB_WIGBR (Q8D2P6) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)|
          Length = 378

 Score = 42.4 bits (98), Expect = 0.001
 Identities = 42/148 (28%), Positives = 66/148 (44%), Gaps = 6/148 (4%)
 Frame = -1

Query: 694 FGAIGMEIAKRLRPFGVKILATKRNWSSNTASCDLDGLVDKKGGPE--EMYELAREADIV 521
           FG IG  + K+L   GVK           T  CD   ++++K   +   + E+ + +DI+
Sbjct: 124 FGNIGKCLNKKLSAIGVK-----------TILCD--PILEEKNNIKLKSLNEIVQNSDII 170

Query: 520 ITCMTLNNESV----GIVNHKFLSTLKKGSYLINIARGRLLDYTAVFNHLESGHLGGLGI 353
              + L          ++N K L  LK    LIN +RG ++D  ++ N L+ G    + +
Sbjct: 171 TLHVPLTYSGKYPTWHLINKKILLDLKDNCILINTSRGSVIDNNSLLNILKEGKPIRVVL 230

Query: 352 DVAWTEPFDPEDPILKFPNVIITPHIAG 269
           DV   EP      +      I TPHIAG
Sbjct: 231 DVWENEPLICSKLLSLID--IGTPHIAG 256

---

>PDXB_SHEON (Q8ECR2) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)|
          Length = 376

 Score = 41.6 bits (96), Expect = 0.002
 Identities = 42/148 (28%), Positives = 63/148 (42%), Gaps = 7/148 (4%)
 Frame = -1

Query: 691 GAIGMEIAKRLRPFGVKILATKRNWSSNTASCDLDGLVDKKGGPEE---MYELAREADIV 521
           G  G   AK L  FG+K+L               D + + +G P +   +  L +EADI+
Sbjct: 126 GNTGSATAKCLEAFGIKVLLN-------------DPIKEAEGDPRDFVSLETLLQEADII 172

Query: 520 ITCMTLNNESVGIVNHKF----LSTLKKGSYLINIARGRLLDYTAVFNHLESGHLGGLGI 353
              + +         H F    L +LK   +LIN  RG ++D  A+    +      L +
Sbjct: 173 SLHVPITRTGEHKTLHLFDEARLMSLKANIWLINCCRGDVIDNQALIKVKQQRDDLKLVL 232

Query: 352 DVAWTEPFDPEDPILKFPNVIITPHIAG 269
           DV   EP +P   ++ F     TPHIAG
Sbjct: 233 DVWEGEP-NPMPELVPFAE-FATPHIAG 258

---

>PDXB_BACTN (Q8A2E4) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)|
          Length = 348

 Score = 41.6 bits (96), Expect = 0.002
 Identities = 35/145 (24%), Positives = 65/145 (44%), Gaps = 4/145 (2%)
 Frame = -1

Query: 691 GAIGMEIAKRLRPFGVKILATKRNWSSNTASCDLDGLVDKKGGPEEMYELAREADIVITC 512
           G +G ++AK  + FG+++L           +     L           ++A E DI+   
Sbjct: 126 GNVGSKVAKVAQDFGMRVLLNDLPREEKEGNITFTSLE----------KIAEECDIITFH 175

Query: 511 MTLNNE----SVGIVNHKFLSTLKKGSYLINIARGRLLDYTAVFNHLESGHLGGLGIDVA 344
           + L  E    +  + +  F  +L++   +IN +RG +++  A+   + +G +    IDV 
Sbjct: 176 VPLYKEGKYKTYHLADGNFFRSLQRKPVVINTSRGEVIETNALLEAINNGIISDAVIDVW 235

Query: 343 WTEPFDPEDPILKFPNVIITPHIAG 269
             EP    + + K   +I TPHIAG
Sbjct: 236 EHEPEINRELLEKV--LIGTPHIAG 258

---

>PDXB_COXBU (Q83AR8) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)|
          Length = 366

 Score = 40.8 bits (94), Expect = 0.004
 Identities = 35/117 (29%), Positives = 58/117 (49%), Gaps = 6/117 (5%)
 Frame = -1

Query: 544 LAREADIVITCM------TLNNESVGIVNHKFLSTLKKGSYLINIARGRLLDYTAVFNHL 383
           LA  A++ + C+      T N  +  +++++FL  LK GS L+N  RG ++D  A+   L
Sbjct: 162 LASLANVDLVCLHTPLVKTGNFPTYHLIDNRFLKMLKPGSVLLNAGRGAVIDNNAL---L 218

Query: 382 ESGHLGGLGIDVAWTEPFDPEDPILKFPNVIITPHIAGITEYSYRTMAKVVGDVALK 212
           +  H+    +DV   EP      + K    I TPHIAG ++ +      ++ D  LK
Sbjct: 219 QCDHVITC-LDVWENEPTVNLQLLEK--TTIATPHIAGYSKQAKLRATLMIYDAFLK 272

---

>PDXB_VIBVY (Q7MIT6) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)|
          Length = 377

 Score = 40.4 bits (93), Expect = 0.005
 Identities = 37/149 (24%), Positives = 65/149 (43%), Gaps = 8/149 (5%)
 Frame = -1

Query: 691 GAIGMEIAKRLRPFGVKILATKRNWSSNTASCDLDGLVDKKGGPEEMYELAR---EADIV 521
           G +G  + + L+  G+K+L               D    ++G   E   L R   EAD++
Sbjct: 126 GQVGSYLQQCLQGIGIKVLIN-------------DPFKQEEGDEREFTSLDRLLQEADVI 172

Query: 520 ITCMTLNNESV----GIVNHKFLSTLKKGSYLINIARGRLLDYTAVFNHLESGHLGGLGI 353
                +  +       ++N + L++L+    LIN ARG ++D  A+ + L+        +
Sbjct: 173 TLHTPITRDGKYPTHHLINKEILNSLRADQILINAARGPVVDNQALKHRLQQADGFTAAL 232

Query: 352 DVAWTEPFDPEDPILKFPNV-IITPHIAG 269
           DV     F+PE  +   P +   TPH+AG
Sbjct: 233 DVF---EFEPEVDMELLPLLAFATPHVAG 258

---

>PDXB_VIBVU (Q8DB36) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)|
          Length = 377

 Score = 40.0 bits (92), Expect = 0.007
 Identities = 37/149 (24%), Positives = 64/149 (42%), Gaps = 8/149 (5%)
 Frame = -1

Query: 691 GAIGMEIAKRLRPFGVKILATKRNWSSNTASCDLDGLVDKKGGPEEMYELAR---EADIV 521
           G +G  + + L+  G+K+L               D    ++G   E   L R   EAD++
Sbjct: 126 GQVGSYLQQCLQGIGIKVLIN-------------DPFKQEEGDEREFTSLDRLLQEADVI 172

Query: 520 ITCMTLNNESV----GIVNHKFLSTLKKGSYLINIARGRLLDYTAVFNHLESGHLGGLGI 353
                +  +       ++N + L++L+    LIN ARG ++D  A+   L+        +
Sbjct: 173 TLHTPITRDGKYPTHHLINEEILNSLRADQILINAARGPVVDNQALKRRLQQADGFMAAL 232

Query: 352 DVAWTEPFDPEDPILKFPNV-IITPHIAG 269
           DV     F+PE  +   P +   TPH+AG
Sbjct: 233 DVF---EFEPEVDMELLPLLAFATPHVAG 258

---

>PDXB_SALTY (P60802) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)|
          Length = 378

 Score = 38.9 bits (89), Expect = 0.015
 Identities = 40/148 (27%), Positives = 65/148 (43%), Gaps = 5/148 (3%)
 Frame = -1

Query: 691 GAIGMEIAKRLRPFGVKILATKRNWSSNTASCDLDGLV-DKKGGPEEMYELAREADIVIT 515
           G +G  +  RL   G++ L            CD        +G    + EL +EAD++  
Sbjct: 125 GNVGSRLQTRLEALGIRTLL-----------CDPPRAARGDEGDFRTLDELVQEADVLTF 173

Query: 514 CMTLNNE----SVGIVNHKFLSTLKKGSYLINIARGRLLDYTAVFNHLESGHLGGLGIDV 347
              L  +    ++ + +   +  LK G+ LIN  RG ++D  A+   L +G    + +DV
Sbjct: 174 HTPLYKDGPYKTLHLADETLIRRLKPGAILINACRGPVVDNAALLARLNAGQPLSVVLDV 233

Query: 346 AWTEPFDPEDPILKFPNVIITPHIAGIT 263
              EP D    +L+  + I T HIAG T
Sbjct: 234 WEGEP-DLNVALLEAVD-IGTSHIAGYT 259

---

>PDXB_SALTI (P60801) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)|
          Length = 378

 Score = 38.9 bits (89), Expect = 0.015
 Identities = 40/148 (27%), Positives = 65/148 (43%), Gaps = 5/148 (3%)
 Frame = -1

Query: 691 GAIGMEIAKRLRPFGVKILATKRNWSSNTASCDLDGLV-DKKGGPEEMYELAREADIVIT 515
           G +G  +  RL   G++ L            CD        +G    + EL +EAD++  
Sbjct: 125 GNVGSRLQTRLEALGIRTLL-----------CDPPRAARGDEGDFRTLDELVQEADVLTF 173

Query: 514 CMTLNNE----SVGIVNHKFLSTLKKGSYLINIARGRLLDYTAVFNHLESGHLGGLGIDV 347
              L  +    ++ + +   +  LK G+ LIN  RG ++D  A+   L +G    + +DV
Sbjct: 174 HTPLYKDGPYKTLHLADETLIRRLKPGAILINACRGPVVDNAALLARLNAGQPLSVVLDV 233

Query: 346 AWTEPFDPEDPILKFPNVIITPHIAGIT 263
              EP D    +L+  + I T HIAG T
Sbjct: 234 WEGEP-DLNVALLEAVD-IGTSHIAGYT 259

---

>PDXB_VIBCH (Q9KQ92) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)|
          Length = 381

 Score = 38.1 bits (87), Expect = 0.025
 Identities = 45/150 (30%), Positives = 66/150 (44%), Gaps = 9/150 (6%)
 Frame = -1

Query: 691 GAIGMEIAKRLRPFGVKILATKRNWSSNTASCDLDGLVDKKGGPEEMYELA---READIV 521
           G +G  +AK L   G+K+L               D     +G   E  EL    ++AD++
Sbjct: 126 GQVGSYLAKCLSGIGMKVLLN-------------DPPKQAQGDEREFTELETLLKQADVI 172

Query: 520 I--TCMTLNNE--SVGIVNHKFLSTLKKGSYLINIARGRLLDYTAVFNHLESGHLGGLGI 353
              T +T   E  +  +++   L  L+    LIN ARG ++D  A+   L+ G      +
Sbjct: 173 TLHTPITRGGEWPTHHLIDAAILEQLRSDQILINAARGPVVDNAALKARLQQGDGFTAVL 232

Query: 352 DVAWTEP-FDPE-DPILKFPNVIITPHIAG 269
           DV   EP  D E  P+L F     TPHIAG
Sbjct: 233 DVFEFEPQVDMELLPLLAF----ATPHIAG 258

---

>PDXB_VIBPA (Q87MN8) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)|
          Length = 377

 Score = 36.6 bits (83), Expect = 0.074
 Identities = 37/149 (24%), Positives = 61/149 (40%), Gaps = 8/149 (5%)
 Frame = -1

Query: 691 GAIGMEIAKRLRPFGVKILATKRNWSSNTASCDLDGLVDKKGGPEE---MYELAREADIV 521
           G +G  + K L+  G+ +L               D    + G P     + EL  ++DI+
Sbjct: 126 GQVGSYLEKCLKGMGINVLIN-------------DPFKQEAGDPRSFTPLAELIEQSDII 172

Query: 520 ITCMTLNNESVGIVNH----KFLSTLKKGSYLINIARGRLLDYTAVFNHLESGHLGGLGI 353
                +  + +   +H    K L+ L+    LIN ARG ++D  A+   L         +
Sbjct: 173 TLHTPITKDGLHPTHHLIDEKVLNGLRGDQILINAARGPVVDNQALKQRLMKQDGFTAAL 232

Query: 352 DVAWTEPFDPEDPILKFPNV-IITPHIAG 269
           DV     F+PE  +   P +   TPH+AG
Sbjct: 233 DVF---EFEPEVDMELLPLLAFATPHVAG 258

---

>PDXB_ERWCT (Q6D2N5) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)|
          Length = 378

 Score = 35.8 bits (81), Expect = 0.13
 Identities = 41/147 (27%), Positives = 63/147 (42%), Gaps = 4/147 (2%)
 Frame = -1

Query: 691 GAIGMEIAKRLRPFGVKILATKRNWSSNTASCDLDGLVDKKGGPEEMYELAREADIVI-- 518
           G +G  +  RL+ +GVK L      +    + D   L            L R+ADI+   
Sbjct: 125 GNVGRRLDTRLKAWGVKTLLCDPPRADRGDAGDFLSLET----------LVRDADILTLH 174

Query: 517 TCMTLNN--ESVGIVNHKFLSTLKKGSYLINIARGRLLDYTAVFNHLESGHLGGLGIDVA 344
           T + L+    +  +V+   L+    G  LIN  RG ++D  A+   L+ G    + +DV 
Sbjct: 175 TPLYLDGPYRTHHLVDATVLNAFADGRILINACRGPVVDNAALLEALQQGKKLSVILDVW 234

Query: 343 WTEPFDPEDPILKFPNVIITPHIAGIT 263
             EP    D + +    I T HIAG T
Sbjct: 235 EPEPGLSTDLLARVD--IGTAHIAGYT 259

---

>PDXB_BLOFL (Q7VRU9) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)|
          Length = 372

 Score = 34.3 bits (77), Expect = 0.37
 Identities = 43/161 (26%), Positives = 70/161 (43%), Gaps = 5/161 (3%)
 Frame = -1

Query: 691 GAIGMEIAKRLRPFGVKILATKRNWSSNTASCDLDGLVDKKGGPEEMYELAREADIVITC 512
           G IG  + +RL   GV  L     +    + CD D +  K      +  L  ++DI+   
Sbjct: 125 GNIGNLLYQRLNSLGVHTLL----YDPYKSKCDTDRMSWKS-----LDILVSKSDILTLH 175

Query: 511 MTLNNESV----GIVNHKFLSTLKKGSYLINIARGRLLDYTAVFNHLESGHLGGLGIDVA 344
           + L          ++N   L  L   S LIN +RG +++   +   L  G    + +DV 
Sbjct: 176 VPLTYTGAYPTWHMINKDILDALPSNSILINTSRGAVVNNDDLLAILRCGKKINVILDVW 235

Query: 343 WTEPFDPEDPILKFPNVIITPHIAGIT-EYSYRTMAKVVGD 224
            +EP     P+L + + I T HIAG + E   R++ K+  D
Sbjct: 236 ESEP-KLSLPLLSYVD-IGTAHIAGYSFESRIRSIKKIYDD 274

---

>PDXB_PHOPR (Q6LNU2) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)|
          Length = 391

 Score = 33.5 bits (75), Expect = 0.63
 Identities = 28/80 (35%), Positives = 39/80 (48%), Gaps = 8/80 (10%)
 Frame = -1

Query: 484 IVNHKFLSTLKKGSYLINIARGRLLDYTAVFNHLESGHLGGLG------IDVAWTEPFDP 323
           ++N  F+  L+  + LIN ARG + D  A+   L+     GLG      +DV   EP   
Sbjct: 189 LINEAFIDALQPDAILINAARGPVTDNQALKKALQLSQ-SGLGKKLTAVLDVFEFEPHVD 247

Query: 322 ED--PILKFPNVIITPHIAG 269
            +  P+L F     TPHIAG
Sbjct: 248 LELLPLLAF----ATPHIAG 263

---

>PDXB_SHESP (Q56731) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)|
           (Fragment)
          Length = 274

 Score = 33.5 bits (75), Expect = 0.63
 Identities = 43/153 (28%), Positives = 67/153 (43%), Gaps = 12/153 (7%)
 Frame = -1

Query: 691 GAIGMEIAKRLRPFGVKILATKRNWSSNTASCDLDGLVDKKGGPEEMYELAREADIVITC 512
           G  G  +AK L+ +GV +L              L   V +   P +   L    D +I C
Sbjct: 13  GNTGSAVAKCLQAYGVTVL--------------LHDPVIQDSDPRDFISL----DELIAC 54

Query: 511 MTLNNESVGIVN---HKF--------LSTLKKGSYLINIARGRLLDYTAVFN-HLESGHL 368
             + +  V I     HK         L++LK+G++L+N  RG ++D  A+    LE   +
Sbjct: 55  CDVISLHVPITKTGEHKTWYLFDEARLNSLKQGTWLLNCCRGEVIDNQALIKVKLERPDI 114

Query: 367 GGLGIDVAWTEPFDPEDPILKFPNVIITPHIAG 269
             L +DV   EP +P   ++     + TPHIAG
Sbjct: 115 -KLVLDVWEGEP-NPMHELIPLVE-LATPHIAG 144

---

>EEP_ENTFA (Q9RPP2) Probable protease eep (EC 3.4.24.-)|
          Length = 422

 Score = 31.6 bits (70), Expect = 2.4
 Identities = 18/59 (30%), Positives = 32/59 (54%), Gaps = 5/59 (8%)
 Frame = -1

Query: 580 VDKKGGPEEMYELAREAD-----IVITCMTLNNESVGIVNHKFLSTLKKGSYLINIARG 419
           ++K GGP  M++L+ EA       V+  M + + ++GI+N   +  L  G  ++NI  G
Sbjct: 325 LNKLGGPVMMFKLSEEASNAGVSTVVFLMAMLSMNLGIINLLPIPALDGGKIVLNIIEG 383

---

>SMCE1_MOUSE (O54941) SWI/SNF-related matrix-associated actin-dependent|
           regulator chromatin subfamily E member 1
           (BRG1-associated factor 57)
          Length = 411

 Score = 31.2 bits (69), Expect = 3.1
 Identities = 20/55 (36%), Positives = 29/55 (52%), Gaps = 4/55 (7%)
 Frame = +3

Query: 291 ITFGNFRIGSS-GSNGSVQATS---MPKPPK*PDSR*LNTAV*SRRRPLAILMRY 443
           + + N+R+G + G+N  V A+S   +PKPPK PD            +PL   MRY
Sbjct: 34  LAYNNYRLGGNPGTNSRVTASSGITIPKPPKPPD------------KPLMPYMRY 76

---

>SMCE1_HUMAN (Q969G3) SWI/SNF-related matrix-associated actin-dependent|
           regulator of chromatin subfamily E member 1
           (BRG1-associated factor 57)
          Length = 411

 Score = 31.2 bits (69), Expect = 3.1
 Identities = 20/55 (36%), Positives = 29/55 (52%), Gaps = 4/55 (7%)
 Frame = +3

Query: 291 ITFGNFRIGSS-GSNGSVQATS---MPKPPK*PDSR*LNTAV*SRRRPLAILMRY 443
           + + N+R+G + G+N  V A+S   +PKPPK PD            +PL   MRY
Sbjct: 34  LAYNNYRLGGNPGTNSRVTASSGITIPKPPKPPD------------KPLMPYMRY 76

---

>PDXB_PSESM (Q884R9) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)|
          Length = 380

 Score = 31.2 bits (69), Expect = 3.1
 Identities = 38/146 (26%), Positives = 64/146 (43%), Gaps = 5/146 (3%)
 Frame = -1

Query: 691 GAIGMEIAKRLRPFGVKILATKRNWSSNTASCDLDGLVDKKGGPEEMYELAREADIVITC 512
           G +G  +   L+  G K+L            CD      + G    + E+ +  D++   
Sbjct: 125 GQVGGRLIAVLKALGWKVLV-----------CDPPRQSAEGGDFVSLDEILQRCDVISLH 173

Query: 511 MTLNNESVG----IVNHKFLSTLKKGSYLINIARGRLLDYTAVFN-HLESGHLGGLGIDV 347
             L+         +++   L  L++G++LIN +RG ++D  A+ +  LE   L  + +DV
Sbjct: 174 TPLDKSGQSPTWHLLDEARLRQLRQGAWLINASRGAVVDNRALHDVMLEREDLQAV-LDV 232

Query: 346 AWTEPFDPEDPILKFPNVIITPHIAG 269
              EP    +  L    VI TPHIAG
Sbjct: 233 WEGEP--QVNVALADLCVIGTPHIAG 256

---

>DHAR_CITFR (P45512) Glycerol metabolism operon regulatory protein|
          Length = 641

 Score = 30.8 bits (68), Expect = 4.1
 Identities = 21/74 (28%), Positives = 36/74 (48%)
 Frame = -1

Query: 670 AKRLRPFGVKILATKRNWSSNTASCDLDGLVDKKGGPEEMYELAREADIVITCMTLNNES 491
           A+RL P  VK++AT         + DL  LV++     ++Y      +IVI  +     S
Sbjct: 450 ARRLIPVDVKVIAT--------TTVDLANLVEQNRFSRQLYYALHSFEIVIPPLRARRNS 501

Query: 490 VGIVNHKFLSTLKK 449
           +  + +  L++LKK
Sbjct: 502 IPSLIYTRLNSLKK 515

---

>SWR1_YARLI (Q6CA87) Helicase SWR1 (EC 3.6.1.-)|
          Length = 1772

 Score = 30.4 bits (67), Expect = 5.3
 Identities = 17/57 (29%), Positives = 29/57 (50%), Gaps = 7/57 (12%)
 Frame = -2

Query: 360  WALMLLGRSHSIQRIQF*NFQMLL*HHTLQES-------RNTLTERWQRLLVMLPSS 211
            W  M+L  +H+I+  +   +Q LL  +T++         +N L E W  L  ++PSS
Sbjct: 1031 WHYMILDEAHNIKNFRSQRWQSLLHFNTVRRLLLTGTPLQNNLMELWSLLYFLMPSS 1087

---

>GUNC_FUSOX (P46237) Endoglucanase type C precursor (EC 3.2.1.4)|
           (Endo-1,4-beta-glucanase) (Cellulase) (Endoglucanase I)
           (EG I)
          Length = 429

 Score = 30.4 bits (67), Expect = 5.3
 Identities = 13/25 (52%), Positives = 16/25 (64%)
 Frame = +3

Query: 291 ITFGNFRIGSSGSNGSVQATSMPKP 365
           +TF N RIG  GS  SV+A + P P
Sbjct: 402 VTFSNIRIGEIGSTSSVKAPAYPGP 426

---

>LYS1_EMENI (Q870G1) Saccharopine dehydrogenase [NAD+, L-lysine-forming] (EC|
           1.5.1.7) (Lysine--2-oxoglutarate reductase) (SDH)
          Length = 375

 Score = 30.4 bits (67), Expect = 5.3
 Identities = 16/39 (41%), Positives = 25/39 (64%)
 Frame = -1

Query: 574 KKGGPEEMYELAREADIVITCMTLNNESVGIVNHKFLST 458
           KKGGP +  E+  +ADI + C+ L+++    VN + LST
Sbjct: 232 KKGGPFK--EIVEDADIFVNCIYLSSKIPHFVNVESLST 268

---

>Y2031_STRP8 (Q8NZB3) Hypothetical zinc metalloprotease spyM18_2031 (EC|
           3.4.24.-)
          Length = 419

 Score = 29.6 bits (65), Expect = 9.1
 Identities = 17/56 (30%), Positives = 32/56 (57%), Gaps = 5/56 (8%)
 Frame = -1

Query: 580 VDKKGGPEEMYELAREA-----DIVITCMTLNNESVGIVNHKFLSTLKKGSYLINI 428
           ++K GGP  MY+++ +A     + V++ M + + ++GI N   +  L  G  L+NI
Sbjct: 322 LNKLGGPVAMYDMSNQAAQNGLESVLSLMAMLSINLGIFNLIPIPALDGGKILMNI 377

---

>Y1963_STRP1 (Q99XY3) Hypothetical zinc metalloprotease SPy1963/M5005_Spy1674|
           (EC 3.4.24.-)
          Length = 419

 Score = 29.6 bits (65), Expect = 9.1
 Identities = 17/56 (30%), Positives = 32/56 (57%), Gaps = 5/56 (8%)
 Frame = -1

Query: 580 VDKKGGPEEMYELAREA-----DIVITCMTLNNESVGIVNHKFLSTLKKGSYLINI 428
           ++K GGP  MY+++ +A     + V++ M + + ++GI N   +  L  G  L+NI
Sbjct: 322 LNKLGGPVAMYDMSNQAAQNGLESVLSLMAMLSINLGIFNLIPIPALDGGKILMNI 377

---

>Y1689_STRP3 (Q8K5S6) Hypothetical zinc metalloprotease SpyM3_1689/SPs1691 (EC|
           3.4.24.-)
          Length = 419

 Score = 29.6 bits (65), Expect = 9.1
 Identities = 17/56 (30%), Positives = 32/56 (57%), Gaps = 5/56 (8%)
 Frame = -1

Query: 580 VDKKGGPEEMYELAREA-----DIVITCMTLNNESVGIVNHKFLSTLKKGSYLINI 428
           ++K GGP  MY+++ +A     + V++ M + + ++GI N   +  L  G  L+NI
Sbjct: 322 LNKLGGPVAMYDMSNQAAQNGLESVLSLMAMLSINLGIFNLIPIPALDGGKILMNI 377

---

>Y1682_STRP6 (Q5X9U6) Hypothetical zinc metalloprotease M6_Spy1682 (EC 3.4.24.-)|
          Length = 419

 Score = 29.6 bits (65), Expect = 9.1
 Identities = 17/56 (30%), Positives = 32/56 (57%), Gaps = 5/56 (8%)
 Frame = -1

Query: 580 VDKKGGPEEMYELAREA-----DIVITCMTLNNESVGIVNHKFLSTLKKGSYLINI 428
           ++K GGP  MY+++ +A     + V++ M + + ++GI N   +  L  G  L+NI
Sbjct: 322 LNKLGGPVAMYDMSNQAAQNGLESVLSLMAMLSINLGIFNLIPIPALDGGKILMNI 377


  Database: uniprot_sprot.fasta
    Posted date:  May 25, 2006  5:36 PM
  Number of letters in database: 80,573,946
  Number of sequences in database:  219,361
  
Lambda     K      H
   0.318    0.135    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 106,124,094
Number of Sequences: 219361
Number of extensions: 2276485
Number of successful extensions: 5852
Number of sequences better than 10.0: 127
Number of HSP's better than 10.0 without gapping: 5600
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5780
length of database: 80,573,946
effective HSP length: 109
effective length of database: 56,663,597
effective search space used: 6856295237
frameshift window, decay const: 50,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)

---