ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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| Clone Name | rbasd13d22 |
|---|---|
| Clone Library Name | barley_pub |
>AKR2_ARATH (Q9SAR5) Ankyrin repeat domain-containing protein 2 (AtAKR2)| Length = 342 Score = 200 bits (509), Expect = 3e-51 Identities = 97/123 (78%), Positives = 111/123 (90%) Frame = -1 Query: 570 SIVHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDA 391 SIVH TAS+GD EGLK AL G +KDEEDSEGR ALHFACGYGE KCA++L++AGA+V+A Sbjct: 220 SIVHQTASLGDVEGLKAALASGGNKDEEDSEGRTALHFACGYGELKCAQVLIDAGASVNA 279 Query: 390 MDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLLEKD 211 +DKNKNTPLHYAAGYGRKECV LLL++GAAVTLQN+D KTPIDVAKLN+Q EV+KLLEKD Sbjct: 280 VDKNKNTPLHYAAGYGRKECVSLLLENGAAVTLQNLDEKTPIDVAKLNSQLEVVKLLEKD 339 Query: 210 VFL 202 FL Sbjct: 340 AFL 342
>TNKS1_HUMAN (O95271) Tankyrase 1 (EC 2.4.2.30) (TANK1) (Tankyrase I) (TNKS-1)| (TRF1-interacting ankyrin-related ADP-ribose polymerase) Length = 1327 Score = 85.1 bits (209), Expect = 2e-16 Identities = 50/121 (41%), Positives = 67/121 (55%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMD 385 +H A ++ L GAD +D G LH AC YG ++ AE+L+ GA+V+ D Sbjct: 688 LHFAAGYNRVSVVEYLLHHGADVHAKDKGGLVPLHNACSYGHYEVAELLVRHGASVNVAD 747 Query: 384 KNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLLEKDVF 205 K TPLH AA G+ E LLLKHGA T +N DG TP+D+ K + D + LL+ D Sbjct: 748 LWKFTPLHEAAAKGKYEICKLLLKHGADPTKKNRDGNTPLDLVKEGDTD-IQDLLKGDAA 806 Query: 204 L 202 L Sbjct: 807 L 807 Score = 77.4 bits (189), Expect = 4e-14 Identities = 42/87 (48%), Positives = 52/87 (59%) Frame = -1 Query: 516 LDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRK 337 L GAD +D G LH AC YG ++ E+LL+ GA V+AMD + TPLH AA R Sbjct: 389 LQHGADVHAKDKGGLVPLHNACSYGHYEVTELLLKHGACVNAMDLWQFTPLHEAASKNRV 448 Query: 336 ECVDLLLKHGAAVTLQNMDGKTPIDVA 256 E LLL HGA TL N GK+ +D+A Sbjct: 449 EVCSLLLSHGADPTLVNCHGKSAVDMA 475 Score = 74.3 bits (181), Expect = 3e-13 Identities = 44/115 (38%), Positives = 63/115 (54%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMD 385 +H A + E + L+ GAD + +D G LH A YG A +L++ V+A D Sbjct: 841 LHLAAGYNNLEVAEYLLEHGADVNAQDKGGLIPLHNAASYGHVDIAALLIKYNTCVNATD 900 Query: 384 KNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 K TPLH AA GR + LLL HGA T++N +G+TP+D+A D++ LL Sbjct: 901 KWAFTPLHEAAQKGRTQLCALLLAHGADPTMKNQEGQTPLDLA---TADDIRALL 952 Score = 70.1 bits (170), Expect = 6e-12 Identities = 39/90 (43%), Positives = 51/90 (56%), Gaps = 2/90 (2%) Frame = -1 Query: 483 SEGRRA--LHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLLKH 310 S+GR++ LH A GY + ++LL+ GA V A DK PLH A YG E +LLLKH Sbjct: 365 SDGRKSTPLHLAAGYNRVRIVQLLLQHGADVHAKDKGGLVPLHNACSYGHYEVTELLLKH 424 Query: 309 GAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 GA V ++ TP+ A N+ EV LL Sbjct: 425 GACVNAMDLWQFTPLHEAASKNRVEVCSLL 454 Score = 68.6 bits (166), Expect = 2e-11 Identities = 44/133 (33%), Positives = 68/133 (51%) Frame = -1 Query: 570 SIVHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDA 391 S +H A G + ++ L GA+ D G LH AC +G + +LL GA +A Sbjct: 218 SPLHFAAGFGRKDVVEHLLQMGANVHARDDGGLIPLHNACSFGHAEVVSLLLCQGADPNA 277 Query: 390 MDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLLEKD 211 D TPLH AA G+ + +LL+HGA ++N DGK+ +D+A + + + +KD Sbjct: 278 RDNWNYTPLHEAAIKGKIDVCIVLLQHGADPNIRNTDGKSALDLADPSAKAVLTGEYKKD 337 Query: 210 VFL*IASLGSHEE 172 L A G+ E+ Sbjct: 338 ELLEAARSGNEEK 350 Score = 53.5 bits (127), Expect = 5e-07 Identities = 45/138 (32%), Positives = 62/138 (44%), Gaps = 21/138 (15%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGY------GEFKCAEILLEAGA 403 +H A G + L GAD + +++G+ AL A GE+K E+L A + Sbjct: 286 LHEAAIKGKIDVCIVLLQHGADPNIRNTDGKSALDLADPSAKAVLTGEYKKDELLEAARS 345 Query: 402 AVD---------------AMDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTP 268 + A D K+TPLH AAGY R V LLL+HGA V ++ G P Sbjct: 346 GNEEKLMALLTPLNVNCHASDGRKSTPLHLAAGYNRVRIVQLLLQHGADVHAKDKGGLVP 405 Query: 267 IDVAKLNNQDEVLKLLEK 214 + A EV +LL K Sbjct: 406 LHNACSYGHYEVTELLLK 423 Score = 48.5 bits (114), Expect = 2e-05 Identities = 34/86 (39%), Positives = 50/86 (58%), Gaps = 2/86 (2%) Frame = -1 Query: 471 RALHFACGYGEFKCAEILLEAGAAVDAMDK--NKNTPLHYAAGYGRKECVDLLLKHGAAV 298 R L AC G+ + L++A A V+A D K++PLH+AAG+GRK+ V+ LL+ GA V Sbjct: 184 RELLEACRNGDVSRVKRLVDA-ANVNAKDMAGRKSSPLHFAAGFGRKDVVEHLLQMGANV 242 Query: 297 TLQNMDGKTPIDVAKLNNQDEVLKLL 220 ++ G P+ A EV+ LL Sbjct: 243 HARDDGGLIPLHNACSFGHAEVVSLL 268 Score = 47.8 bits (112), Expect = 3e-05 Identities = 39/139 (28%), Positives = 56/139 (40%), Gaps = 22/139 (15%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMD 385 +H A+ G E K L GAD +++ +G L G+ ++L A +DA Sbjct: 754 LHEAAAKGKYEICKLLLKHGADPTKKNRDGNTPLDLV-KEGDTDIQDLLKGDAALLDAAK 812 Query: 384 KN----------------------KNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKT 271 K +TPLH AAGY E + LL+HGA V Q+ G Sbjct: 813 KGCLARVQKLCTPENINCRDTQGRNSTPLHLAAGYNNLEVAEYLLEHGADVNAQDKGGLI 872 Query: 270 PIDVAKLNNQDEVLKLLEK 214 P+ A ++ LL K Sbjct: 873 PLHNAASYGHVDIAALLIK 891 Score = 43.5 bits (101), Expect = 6e-04 Identities = 23/57 (40%), Positives = 32/57 (56%) Frame = -1 Query: 390 MDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 ++ +TPLH+AAGY R V+ LL HGA V ++ G P+ A EV +LL Sbjct: 680 LEGRHSTPLHFAAGYNRVSVVEYLLHHGADVHAKDKGGLVPLHNACSYGHYEVAELL 736 Score = 42.0 bits (97), Expect = 0.002 Identities = 24/69 (34%), Positives = 38/69 (55%) Frame = -1 Query: 426 EILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLN 247 E+LL GA V+ +K+ TPLH AA + +++L KHGA + + G+T + A L Sbjct: 542 ELLLRKGANVNEKNKDFMTPLHVAAERAHNDVMEVLHKHGAKMNALDTLGQTALHRAALA 601 Query: 246 NQDEVLKLL 220 + +LL Sbjct: 602 GHLQTCRLL 610 Score = 39.3 bits (90), Expect = 0.011 Identities = 26/89 (29%), Positives = 46/89 (51%) Frame = -1 Query: 507 GADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECV 328 GA+ +E++ + LH A E+L + GA ++A+D T LH AA G + Sbjct: 548 GANVNEKNKDFMTPLHVAAERAHNDVMEVLHKHGAKMNALDTLGQTALHRAALAGHLQTC 607 Query: 327 DLLLKHGAAVTLQNMDGKTPIDVAKLNNQ 241 LLL +G+ ++ ++ G T A++ N+ Sbjct: 608 RLLLSYGSDPSIISLQGFT---AAQMGNE 633 Score = 35.0 bits (79), Expect = 0.20 Identities = 21/60 (35%), Positives = 33/60 (55%), Gaps = 3/60 (5%) Frame = -1 Query: 384 KNKNTPLHYAAGY---GRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLLEK 214 ++ T LH A RK+ +LLL+ GA V +N D TP+ VA ++V+++L K Sbjct: 520 QSHETALHCAVASLHPKRKQVTELLLRKGANVNEKNKDFMTPLHVAAERAHNDVMEVLHK 579
>TNKS2_HUMAN (Q9H2K2) Tankyrase 2 (EC 2.4.2.30) (TANK2) (Tankyrase II) (TNKS-2)| (TRF1-interacting ankyrin-related ADP-ribose polymerase 2) (Tankyrase-like protein) (Tankyrase-related protein) Length = 1166 Score = 83.2 bits (204), Expect = 6e-16 Identities = 48/121 (39%), Positives = 66/121 (54%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMD 385 +H A ++ L GAD +D G LH AC YG ++ AE+L++ GA V+ D Sbjct: 530 LHFAAGYNRVSVVEYLLQHGADVHAKDKGGLVPLHNACSYGHYEVAELLVKHGAVVNVAD 589 Query: 384 KNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLLEKDVF 205 K TPLH AA G+ E LLL+HGA T +N DG TP+D+ K + ++ LL D Sbjct: 590 LWKFTPLHEAAAKGKYEICKLLLQHGADPTKKNRDGNTPLDLVK-DGDTDIQDLLRGDAA 648 Query: 204 L 202 L Sbjct: 649 L 649 Score = 75.1 bits (183), Expect = 2e-13 Identities = 43/112 (38%), Positives = 61/112 (54%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMD 385 +H A + E + L GAD + +D G LH A YG A +L++ A V+A D Sbjct: 683 LHLAAGYNNLEVAEYLLQHGADVNAQDKGGLIPLHNAASYGHVDVAALLIKYNACVNATD 742 Query: 384 KNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVL 229 K TPLH AA GR + LLL HGA TL+N +G+TP+D+ ++ +L Sbjct: 743 KWAFTPLHEAAQKGRTQLCALLLAHGADPTLKNQEGQTPLDLVSADDVSALL 794 Score = 72.8 bits (177), Expect = 9e-13 Identities = 44/131 (33%), Positives = 68/131 (51%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMD 385 +H A G + ++ L GA+ D G LH AC +G + +LL GA +A D Sbjct: 62 LHFAAGFGRKDVVEYLLQNGANVQARDDGGLIPLHNACSFGHAEVVNLLLRHGADPNARD 121 Query: 384 KNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLLEKDVF 205 TPLH AA G+ + +LL+HGA T++N DG+T +D+A + + + +KD Sbjct: 122 NWNYTPLHEAAIKGKIDVCIVLLQHGAEPTIRNTDGRTALDLADPSAKAVLTGEYKKDEL 181 Query: 204 L*IASLGSHEE 172 L A G+ E+ Sbjct: 182 LESARSGNEEK 192 Score = 70.5 bits (171), Expect = 4e-12 Identities = 39/90 (43%), Positives = 51/90 (56%), Gaps = 2/90 (2%) Frame = -1 Query: 483 SEGRRA--LHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLLKH 310 S+GR++ LH A GY K ++LL+ GA V A DK PLH A YG E +LL+KH Sbjct: 207 SDGRKSTPLHLAAGYNRVKIVQLLLQHGADVHAKDKGDLVPLHNACSYGHYEVTELLVKH 266 Query: 309 GAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 GA V ++ TP+ A N+ EV LL Sbjct: 267 GACVNAMDLWQFTPLHEAASKNRVEVCSLL 296 Score = 69.3 bits (168), Expect = 1e-11 Identities = 39/87 (44%), Positives = 50/87 (57%) Frame = -1 Query: 516 LDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRK 337 L GAD +D LH AC YG ++ E+L++ GA V+AMD + TPLH AA R Sbjct: 231 LQHGADVHAKDKGDLVPLHNACSYGHYEVTELLVKHGACVNAMDLWQFTPLHEAASKNRV 290 Query: 336 ECVDLLLKHGAAVTLQNMDGKTPIDVA 256 E LLL +GA TL N K+ ID+A Sbjct: 291 EVCSLLLSYGADPTLLNCHNKSAIDLA 317 Score = 61.2 bits (147), Expect = 3e-09 Identities = 35/91 (38%), Positives = 49/91 (53%), Gaps = 2/91 (2%) Frame = -1 Query: 486 DSEGRRA--LHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLLK 313 D++GR + LH A GY + AE LL+ GA V+A DK PLH AA YG + LL+K Sbjct: 674 DTQGRHSTPLHLAAGYNNLEVAEYLLQHGADVNAQDKGGLIPLHNAASYGHVDVAALLIK 733 Query: 312 HGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 + A V + TP+ A + ++ LL Sbjct: 734 YNACVNATDKWAFTPLHEAAQKGRTQLCALL 764 Score = 50.8 bits (120), Expect = 4e-06 Identities = 44/138 (31%), Positives = 61/138 (44%), Gaps = 21/138 (15%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGY------GEFKCAEILLEAGA 403 +H A G + L GA+ +++GR AL A GE+K E+L A + Sbjct: 128 LHEAAIKGKIDVCIVLLQHGAEPTIRNTDGRTALDLADPSAKAVLTGEYKKDELLESARS 187 Query: 402 AVD---------------AMDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTP 268 + A D K+TPLH AAGY R + V LLL+HGA V ++ P Sbjct: 188 GNEEKMMALLTPLNVNCHASDGRKSTPLHLAAGYNRVKIVQLLLQHGADVHAKDKGDLVP 247 Query: 267 IDVAKLNNQDEVLKLLEK 214 + A EV +LL K Sbjct: 248 LHNACSYGHYEVTELLVK 265 Score = 48.1 bits (113), Expect = 2e-05 Identities = 40/139 (28%), Positives = 56/139 (40%), Gaps = 22/139 (15%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMD 385 +H A+ G E K L GAD +++ +G L G+ ++L A +DA Sbjct: 596 LHEAAAKGKYEICKLLLQHGADPTKKNRDGNTPLDLVKD-GDTDIQDLLRGDAALLDAAK 654 Query: 384 KN----------------------KNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKT 271 K +TPLH AAGY E + LL+HGA V Q+ G Sbjct: 655 KGCLARVKKLSSPDNVNCRDTQGRHSTPLHLAAGYNNLEVAEYLLQHGADVNAQDKGGLI 714 Query: 270 PIDVAKLNNQDEVLKLLEK 214 P+ A +V LL K Sbjct: 715 PLHNAASYGHVDVAALLIK 733 Score = 47.8 bits (112), Expect = 3e-05 Identities = 32/86 (37%), Positives = 49/86 (56%), Gaps = 2/86 (2%) Frame = -1 Query: 471 RALHFACGYGEFKCAEILLEAGAAVDAMDK--NKNTPLHYAAGYGRKECVDLLLKHGAAV 298 R L AC G+ + + L+ V++ D K+TPLH+AAG+GRK+ V+ LL++GA V Sbjct: 26 RELFEACRNGDVERVKRLVTP-EKVNSRDTAGRKSTPLHFAAGFGRKDVVEYLLQNGANV 84 Query: 297 TLQNMDGKTPIDVAKLNNQDEVLKLL 220 ++ G P+ A EV+ LL Sbjct: 85 QARDDGGLIPLHNACSFGHAEVVNLL 110 Score = 45.8 bits (107), Expect = 1e-04 Identities = 24/59 (40%), Positives = 35/59 (59%) Frame = -1 Query: 390 MDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLLEK 214 ++ ++TPLH+AAGY R V+ LL+HGA V ++ G P+ A EV +LL K Sbjct: 522 IEGRQSTPLHFAAGYNRVSVVEYLLQHGADVHAKDKGGLVPLHNACSYGHYEVAELLVK 580 Score = 40.4 bits (93), Expect = 0.005 Identities = 32/111 (28%), Positives = 53/111 (47%) Frame = -1 Query: 507 GADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECV 328 GA+ +E+ E LH A E++++ A V+A+D T LH AA G + Sbjct: 390 GANINEKTKEFLTPLHVASEKAHNDVVEVVVKHEAKVNALDNLGQTSLHRAAYCGHLQTC 449 Query: 327 DLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLLEKDVFL*IASLGSHE 175 LLL +G + ++ G T + + N V +LL++ + SLG+ E Sbjct: 450 RLLLSYGCDPNIISLQGFTALQMGNEN----VQQLLQEGI-----SLGNSE 491 Score = 35.8 bits (81), Expect = 0.12 Identities = 21/69 (30%), Positives = 35/69 (50%) Frame = -1 Query: 426 EILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLN 247 E+LL GA ++ K TPLH A+ + V++++KH A V + G+T + A Sbjct: 384 ELLLRKGANINEKTKEFLTPLHVASEKAHNDVVEVVVKHEAKVNALDNLGQTSLHRAAYC 443 Query: 246 NQDEVLKLL 220 + +LL Sbjct: 444 GHLQTCRLL 452
>ANR28_HUMAN (O15084) Ankyrin repeat domain-containing protein 28| Length = 1086 Score = 75.9 bits (185), Expect = 1e-13 Identities = 45/115 (39%), Positives = 59/115 (51%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMD 385 +HH A G GE +K L GA+ + D + RRA+H+A G + ++L+ GA V D Sbjct: 177 LHHAAFSGHGEMVKLLLSRGANINAFDKKDRRAIHWAAYMGHIEVVKLLVSHGAEVTCKD 236 Query: 384 KNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 K TPLH AA G V LL G + N G TP+ VA N QD V+ L Sbjct: 237 KKSYTPLHAAASSGMISVVKYLLDLGVDMNEPNAYGNTPLHVACYNGQDVVVNEL 291 Score = 68.2 bits (165), Expect = 2e-11 Identities = 52/148 (35%), Positives = 73/148 (49%), Gaps = 4/148 (2%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADK----DEEDSEGRRALHFACGYGEFKCAEILLEAGAAV 397 +H A+ G E L+ L G A+ D +D G+ L + G C LL GA V Sbjct: 654 IHAAATNGHSECLR-LLIGNAEPQNAVDIQDGNGQTPLMLSVLNGHTDCVYSLLNKGANV 712 Query: 396 DAMDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLLE 217 DA DK T LH A G +ECVD LL+HGA L++ G+TPI ++ VL L Sbjct: 713 DAKDKWGRTALHRGAVTGHEECVDALLQHGAKCLLRDSRGRTPIHLSAACGHIGVLGALL 772 Query: 216 KDVFL*IASLGSHEETWPSSCFTSLWHW 133 + AS+ ++ T + +T+L HW Sbjct: 773 QSA----ASMDANPATADNHGYTAL-HW 795 Score = 67.8 bits (164), Expect = 3e-11 Identities = 32/103 (31%), Positives = 57/103 (55%) Frame = -1 Query: 528 LKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAG 349 L+ + GAD + + +G+ LH +G F ++ ++++GA +D DKN NTPLH AA Sbjct: 322 LELLVGNGADVNMKSKDGKTPLHMTALHGRFSRSQTIIQSGAVIDCEDKNGNTPLHIAAR 381 Query: 348 YGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 YG + ++ L+ GA + + G P+ +A L+ + + L Sbjct: 382 YGHELLINTLITSGADTAKRGIHGMFPLHLAALSGFSDCCRKL 424 Score = 66.2 bits (160), Expect = 8e-11 Identities = 38/109 (34%), Positives = 61/109 (55%), Gaps = 1/109 (0%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMD 385 +H AS G +K LD G D +E ++ G LH AC G+ L++ GA V+ + Sbjct: 243 LHAAASSGMISVVKYLLDLGVDMNEPNAYGNTPLHVACYNGQDVVVNELIDCGAIVNQKN 302 Query: 384 KNKNTPLHYAAGYGRKE-CVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQ 241 + TPLH+AA C++LL+ +GA V +++ DGKTP+ + L+ + Sbjct: 303 EKGFTPLHFAAASTHGALCLELLVGNGADVNMKSKDGKTPLHMTALHGR 351 Score = 65.1 bits (157), Expect = 2e-10 Identities = 38/109 (34%), Positives = 53/109 (48%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMD 385 +H A G + +K L G D D D GR LH A G +C +LL GA + D Sbjct: 409 LHLAALSGFSDCCRKLLSSGFDIDTPDDFGRTCLHAAAAGGNLECLNLLLNTGADFNKKD 468 Query: 384 KNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQD 238 K +PLHYAA +C+ L+ GA+V + G TP+ A ++ D Sbjct: 469 KFGRSPLHYAAANCNYQCLFALVGSGASVNDLDERGCTPLHYAATSDTD 517 Score = 61.6 bits (148), Expect = 2e-09 Identities = 34/89 (38%), Positives = 47/89 (52%) Frame = -1 Query: 486 DSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLLKHG 307 D GR ALH A G + ++LL GA ++A DK +H+AA G E V LL+ HG Sbjct: 170 DRAGRTALHHAAFSGHGEMVKLLLSRGANINAFDKKDRRAIHWAAYMGHIEVVKLLVSHG 229 Query: 306 AAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 A VT ++ TP+ A + V+K L Sbjct: 230 AEVTCKDKKSYTPLHAAASSGMISVVKYL 258 Score = 61.2 bits (147), Expect = 3e-09 Identities = 34/99 (34%), Positives = 55/99 (55%) Frame = -1 Query: 543 GDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPL 364 GD + ++ + D + +D+E R LH A G+ + E+L+ +GA V+A D TPL Sbjct: 52 GDPDEVRALIFKKEDVNFQDNEKRTPLHAAAYLGDAEIIELLILSGARVNAKDSKWLTPL 111 Query: 363 HYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLN 247 H A +E V +LLKH A V ++ + +TP+ +A N Sbjct: 112 HRAVASCSEEAVQVLLKHSADVNARDKNWQTPLHIAAAN 150 Score = 60.5 bits (145), Expect = 4e-09 Identities = 42/124 (33%), Positives = 65/124 (52%), Gaps = 5/124 (4%) Frame = -1 Query: 570 SIVHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDA 391 S +H A G + L+ + D D +S GR L A G +C ++L+ GA++ Sbjct: 585 SPLHLAAYHGHHQALEVLVQSLLDLDVRNSSGRTPLDLAAFKGHVECVDVLINQGASILV 644 Query: 390 MDKN-KNTPLHYAAGYGRKECVDLLLKHGA---AVTLQNMDGKTPIDVAKLN-NQDEVLK 226 D K TP+H AA G EC+ LL+ + AV +Q+ +G+TP+ ++ LN + D V Sbjct: 645 KDYILKRTPIHAAATNGHSECLRLLIGNAEPQNAVDIQDGNGQTPLMLSVLNGHTDCVYS 704 Query: 225 LLEK 214 LL K Sbjct: 705 LLNK 708 Score = 59.7 bits (143), Expect = 8e-09 Identities = 48/153 (31%), Positives = 64/153 (41%), Gaps = 38/153 (24%) Frame = -1 Query: 564 VHHTASVGD----GEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEA---- 409 +H +A+ G G L+ A A+ D+ G ALH+AC G C E+LLE Sbjct: 756 IHLSAACGHIGVLGALLQSAASMDANPATADNHGYTALHWACYNGHETCVELLLEQEVFQ 815 Query: 408 -------------------GAA-----------VDAMDKNKNTPLHYAAGYGRKECVDLL 319 GAA V+A D TPLH AA EC+ LL Sbjct: 816 KTEGNAFSPLHCAVINDNEGAAEMLIDTLGASIVNATDSKGRTPLHAAAFTDHVECLQLL 875 Query: 318 LKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 L H A V + GKTP+ +A N Q +++L Sbjct: 876 LSHNAQVNSVDSTGKTPLMMAAENGQTNTVEML 908 Score = 58.9 bits (141), Expect = 1e-08 Identities = 36/115 (31%), Positives = 60/115 (52%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMD 385 +H A +GD E ++ + GA + +DS+ LH A + ++LL+ A V+A D Sbjct: 78 LHAAAYLGDAEIIELLILSGARVNAKDSKWLTPLHRAVASCSEEAVQVLLKHSADVNARD 137 Query: 384 KNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 KN TPLH AA +C + L+ + V + + G+T + A + E++KLL Sbjct: 138 KNWQTPLHIAAANKAVKCAEALVPLLSNVNVSDRAGRTALHHAAFSGHGEMVKLL 192 Score = 55.1 bits (131), Expect = 2e-07 Identities = 32/93 (34%), Positives = 52/93 (55%), Gaps = 4/93 (4%) Frame = -1 Query: 486 DSEGRRA---LHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLL 316 DS+ R LH A +G + E+L+++ +D + + TPL AA G ECVD+L+ Sbjct: 577 DSDNRATISPLHLAAYHGHHQALEVLVQSLLDLDVRNSSGRTPLDLAAFKGHVECVDVLI 636 Query: 315 KHGAAVTLQN-MDGKTPIDVAKLNNQDEVLKLL 220 GA++ +++ + +TPI A N E L+LL Sbjct: 637 NQGASILVKDYILKRTPIHAAATNGHSECLRLL 669 Score = 54.7 bits (130), Expect = 2e-07 Identities = 38/120 (31%), Positives = 61/120 (50%), Gaps = 5/120 (4%) Frame = -1 Query: 558 HTASVGDGEGLKKALD---GGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAM 388 H A + D EG + L G + + DS+GR LH A +C ++LL A V+++ Sbjct: 826 HCAVINDNEGAAEMLIDTLGASIVNATDSKGRTPLHAAAFTDHVECLQLLLSHNAQVNSV 885 Query: 387 DKNKNTPLHYAAGYGRKECVDLLLKHGAA-VTLQNMDGKTPIDVA-KLNNQDEVLKLLEK 214 D TPL AA G+ V++L+ +A +TLQ+ T + +A ++ L +LEK Sbjct: 886 DSTGKTPLMMAAENGQTNTVEMLVSSASAELTLQDNSKNTALHLACSKGHETSALLILEK 945 Score = 53.1 bits (126), Expect = 7e-07 Identities = 36/115 (31%), Positives = 51/115 (44%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMD 385 +H + E ++ L AD + D + LH A KCAE L+ + V+ D Sbjct: 111 LHRAVASCSEEAVQVLLKHSADVNARDKNWQTPLHIAAANKAVKCAEALVPLLSNVNVSD 170 Query: 384 KNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 + T LH+AA G E V LLL GA + + + I A EV+KLL Sbjct: 171 RAGRTALHHAAFSGHGEMVKLLLSRGANINAFDKKDRRAIHWAAYMGHIEVVKLL 225 Score = 52.8 bits (125), Expect = 9e-07 Identities = 34/106 (32%), Positives = 47/106 (44%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMD 385 +H A G + + GAD + G LH A G C LL +G +D D Sbjct: 376 LHIAARYGHELLINTLITSGADTAKRGIHGMFPLHLAALSGFSDCCRKLLSSGFDIDTPD 435 Query: 384 KNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLN 247 T LH AA G EC++LLL GA ++ G++P+ A N Sbjct: 436 DFGRTCLHAAAAGGNLECLNLLLNTGADFNKKDKFGRSPLHYAAAN 481 Score = 52.8 bits (125), Expect = 9e-07 Identities = 31/105 (29%), Positives = 55/105 (52%), Gaps = 2/105 (1%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACG--YGEFKCAEILLEAGAAVDA 391 +H G + + +D GA ++++ +G LHFA +G C E+L+ GA V+ Sbjct: 276 LHVACYNGQDVVVNELIDCGAIVNQKNEKGFTPLHFAAASTHGAL-CLELLVGNGADVNM 334 Query: 390 MDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVA 256 K+ TPLH A +GR +++ GA + ++ +G TP+ +A Sbjct: 335 KSKDGKTPLHMTALHGRFSRSQTIIQSGAVIDCEDKNGNTPLHIA 379 Score = 49.3 bits (116), Expect = 1e-05 Identities = 39/161 (24%), Positives = 69/161 (42%), Gaps = 46/161 (28%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMD 385 +H A+ G+ E L L+ GAD +++D GR LH+A ++C L+ +GA+V+ +D Sbjct: 442 LHAAAAGGNLECLNLLLNTGADFNKKDKFGRSPLHYAAANCNYQCLFALVGSGASVNDLD 501 Query: 384 KNKNTPLHYAA----------------------------------GYGRKEC-------- 331 + TPLHYAA YG + C Sbjct: 502 ERGCTPLHYAATSDTDGKCLEYLLRNDANPGVRDKQGYNAVHYSAAYGHRLCLQLIASET 561 Query: 330 -VDLLLKHGAAVTLQNMDGK---TPIDVAKLNNQDEVLKLL 220 +D+L++ L + D + +P+ +A + + L++L Sbjct: 562 PLDVLMETSGTDMLSDSDNRATISPLHLAAYHGHHQALEVL 602 Score = 40.8 bits (94), Expect = 0.004 Identities = 24/78 (30%), Positives = 40/78 (51%) Frame = -1 Query: 399 VDAMDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 V+ D K TPLH AA G E ++LL+ GA V ++ TP+ A + +E +++L Sbjct: 67 VNFQDNEKRTPLHAAAYLGDAEIIELLILSGARVNAKDSKWLTPLHRAVASCSEEAVQVL 126 Query: 219 EKDVFL*IASLGSHEETW 166 K A + + ++ W Sbjct: 127 LKH----SADVNARDKNW 140
>ANR12_HUMAN (Q6UB98) Ankyrin repeat domain-containing protein 12 (Ankyrin| repeat-containing cofactor 2) (GAC-1 protein) Length = 2062 Score = 75.5 bits (184), Expect = 1e-13 Identities = 41/113 (36%), Positives = 64/113 (56%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMD 385 +H A GD + +K+ + GA+ + +D G LH AC G + A+IL+ AGA V+ Sbjct: 189 LHMAAIRGDVKQVKELISLGANVNVKDFAGWTPLHEACNVGYYDVAKILIAAGADVNTQG 248 Query: 384 KNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLK 226 + +TPLH +A G ++ V LLL+HG N G+ P+DVA+ + +LK Sbjct: 249 LDDDTPLHDSASSGHRDIVKLLLRHGGNAFQANKHGERPVDVAETEELELLLK 301 Score = 49.3 bits (116), Expect = 1e-05 Identities = 28/92 (30%), Positives = 45/92 (48%) Frame = -1 Query: 495 DEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLL 316 ++ + G LH A G+ K + L+ GA V+ D TPLH A G + +L+ Sbjct: 179 NKRNERGETPLHMAAIRGDVKQVKELISLGANVNVKDFAGWTPLHEACNVGYYDVAKILI 238 Query: 315 KHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 GA V Q +D TP+ + + +++KLL Sbjct: 239 AAGADVNTQGLDDDTPLHDSASSGHRDIVKLL 270 Score = 29.6 bits (65), Expect = 8.5 Identities = 20/60 (33%), Positives = 31/60 (51%) Frame = -1 Query: 399 VDAMDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 V+ ++ TPLH AA G + V L+ GA V +++ G TP+ A +V K+L Sbjct: 178 VNKRNERGETPLHMAAIRGDVKQVKELISLGANVNVKDFAGWTPLHEACNVGYYDVAKIL 237
>ASB8_MOUSE (Q91ZT9) Ankyrin repeat and SOCS box protein 8 (ASB-8)| Length = 288 Score = 74.3 bits (181), Expect = 3e-13 Identities = 42/115 (36%), Positives = 64/115 (55%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMD 385 +H V D + ++ L+ GA+ + D R ALH+A E C E+LLE GA +A+D Sbjct: 57 LHCACMVSDADCVELLLEKGAEVNALDGYNRTALHYAAERDE-ACVEVLLEYGANPNALD 115 Query: 384 KNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 N++TPLH+AA ECV LL+ GA+V + + TP+ A + E + +L Sbjct: 116 GNRDTPLHWAAFKNNAECVRALLESGASVNALDYNNDTPLSWAAMKGNLESVSIL 170 Score = 68.2 bits (165), Expect = 2e-11 Identities = 38/98 (38%), Positives = 57/98 (58%) Frame = -1 Query: 558 HTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKN 379 H A+ D ++ L+ GA+ + D LH+A +C LLE+GA+V+A+D N Sbjct: 91 HYAAERDEACVEVLLEYGANPNALDGNRDTPLHWAAFKNNAECVRALLESGASVNALDYN 150 Query: 378 KNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPI 265 +TPL +AA G E V +LL +GA V + N+ G+TPI Sbjct: 151 NDTPLSWAAMKGNLESVSILLDYGAEVRVINLKGQTPI 188 Score = 57.8 bits (138), Expect = 3e-08 Identities = 36/105 (34%), Positives = 56/105 (53%) Frame = -1 Query: 534 EGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYA 355 + ++ + GGAD + + LH AC + C E+LLE GA V+A+D T LHYA Sbjct: 35 DNVEDLIRGGADVNCTHGT-LKPLHCACMVSDADCVELLLEKGAEVNALDGYNRTALHYA 93 Query: 354 AGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 A + CV++LL++GA + + TP+ A N E ++ L Sbjct: 94 AERD-EACVEVLLEYGANPNALDGNRDTPLHWAAFKNNAECVRAL 137 Score = 30.4 bits (67), Expect = 5.0 Identities = 31/123 (25%), Positives = 51/123 (41%), Gaps = 8/123 (6%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMD 385 +H A + E ++ L+ GA + D L +A G + ILL+ GA V ++ Sbjct: 122 LHWAAFKNNAECVRALLESGASVNALDYNNDTPLSWAAMKGNLESVSILLDYGAEVRVIN 181 Query: 384 KNKNTPLH-----YAAGYGRKE---CVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVL 229 TP+ G G ++ C +LL + L+ +G P +V K E L Sbjct: 182 LKGQTPISRLVALLVRGLGTEKEDSCFELLHRAVGQFELRK-NGIMPREVTKDQQLCEKL 240 Query: 228 KLL 220 +L Sbjct: 241 TVL 243 Score = 30.0 bits (66), Expect = 6.5 Identities = 23/70 (32%), Positives = 33/70 (47%) Frame = -1 Query: 426 EILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLN 247 E L+ GA V+ PLH A +CV+LLL+ GA V + +T + A Sbjct: 38 EDLIRGGADVNCTHGTLK-PLHCACMVSDADCVELLLEKGAEVNALDGYNRTALHYAAER 96 Query: 246 NQDEVLKLLE 217 ++ V LLE Sbjct: 97 DEACVEVLLE 106
>ASB8_HUMAN (Q9H765) Ankyrin repeat and SOCS box protein 8 (ASB-8)| Length = 288 Score = 74.3 bits (181), Expect = 3e-13 Identities = 42/115 (36%), Positives = 64/115 (55%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMD 385 +H V D + ++ L+ GA+ + D R ALH+A E C E+LLE GA +A+D Sbjct: 57 LHCACMVSDADCVELLLEKGAEVNALDGYNRTALHYAAEKDE-ACVEVLLEYGANPNALD 115 Query: 384 KNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 N++TPLH+AA ECV LL+ GA+V + + TP+ A + E + +L Sbjct: 116 GNRDTPLHWAAFKNNAECVRALLESGASVNALDYNNDTPLSWAAMKGNLESVSIL 170 Score = 67.4 bits (163), Expect = 4e-11 Identities = 38/98 (38%), Positives = 57/98 (58%) Frame = -1 Query: 558 HTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKN 379 H A+ D ++ L+ GA+ + D LH+A +C LLE+GA+V+A+D N Sbjct: 91 HYAAEKDEACVEVLLEYGANPNALDGNRDTPLHWAAFKNNAECVRALLESGASVNALDYN 150 Query: 378 KNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPI 265 +TPL +AA G E V +LL +GA V + N+ G+TPI Sbjct: 151 NDTPLSWAAMKGNLESVSILLDYGAEVRVINLIGQTPI 188 Score = 57.8 bits (138), Expect = 3e-08 Identities = 36/105 (34%), Positives = 56/105 (53%) Frame = -1 Query: 534 EGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYA 355 + ++ + GGAD + + LH AC + C E+LLE GA V+A+D T LHYA Sbjct: 35 DNVEDLIRGGADVNCTHGT-LKPLHCACMVSDADCVELLLEKGAEVNALDGYNRTALHYA 93 Query: 354 AGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 A + CV++LL++GA + + TP+ A N E ++ L Sbjct: 94 AEKD-EACVEVLLEYGANPNALDGNRDTPLHWAAFKNNAECVRAL 137 Score = 30.0 bits (66), Expect = 6.5 Identities = 23/70 (32%), Positives = 33/70 (47%) Frame = -1 Query: 426 EILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLN 247 E L+ GA V+ PLH A +CV+LLL+ GA V + +T + A Sbjct: 38 EDLIRGGADVNCTHGTLK-PLHCACMVSDADCVELLLEKGAEVNALDGYNRTALHYAAEK 96 Query: 246 NQDEVLKLLE 217 ++ V LLE Sbjct: 97 DEACVEVLLE 106
>ASB10_MOUSE (Q91ZT7) Ankyrin repeat and SOCS box protein 10 (ASB-10)| Length = 467 Score = 74.3 bits (181), Expect = 3e-13 Identities = 40/101 (39%), Positives = 57/101 (56%), Gaps = 1/101 (0%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMD 385 +H S G ++ L GAD + D +G+R LH G G +C E+LL+ GA VD Sbjct: 152 LHEACSAGHAACVRVLLVAGADPNTLDQDGKRPLHLCRGPGILECVELLLKFGAQVDGRT 211 Query: 384 KNKN-TPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPI 265 +++ TPLH AA G E DLLL+ GA ++N +G TP+ Sbjct: 212 EDEEETPLHIAARLGHVELADLLLRWGACPDVRNSEGWTPL 252 Score = 67.4 bits (163), Expect = 4e-11 Identities = 46/116 (39%), Positives = 59/116 (50%), Gaps = 1/116 (0%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMD 385 +H AS G E L+ L A D GR ALH AC G C +LL AGA + +D Sbjct: 120 LHVAASRGHTEVLELLLRRRAKPDSAPG-GRTALHEACSAGHAACVRVLLVAGADPNTLD 178 Query: 384 KNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMD-GKTPIDVAKLNNQDEVLKLL 220 ++ PLH G G ECV+LLLK GA V + D +TP+ +A E+ LL Sbjct: 179 QDGKRPLHLCRGPGILECVELLLKFGAQVDGRTEDEEETPLHIAARLGHVELADLL 234 Score = 49.7 bits (117), Expect = 8e-06 Identities = 49/169 (28%), Positives = 63/169 (37%), Gaps = 15/169 (8%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGE-------------FKCAE 424 +H A +G E L GA D +SEG L AC F+ Sbjct: 219 LHIAARLGHVELADLLLRWGACPDVRNSEGWTPLLAACDIRCQSPKDAEATTNRCFQLCR 278 Query: 423 ILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNN 244 +LL GA DA +++K PLH A +G V LLL G + G TP+ A L Sbjct: 279 LLLSVGADADAANQDKQRPLHLACRHGHSAVVQLLLSCGVNANAMDYGGHTPLHCALLGP 338 Query: 243 QDEVLKLLEKDVFL*IASLGSH--EETWPSSCFTSLWHWLDSHTRIGIL 103 V E V L +H WP + L W S I +L Sbjct: 339 TTAVAHSPEHTV----RDLLNHGAVRVWPGALPKVLDRWCMSPRTIEVL 383 Score = 40.0 bits (92), Expect = 0.006 Identities = 28/84 (33%), Positives = 39/84 (46%) Frame = -1 Query: 465 LHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQN 286 LH A G + E+LL A D+ + T LH A G CV +LL GA + Sbjct: 120 LHVAASRGHTEVLELLLRRRAKPDSAPGGR-TALHEACSAGHAACVRVLLVAGADPNTLD 178 Query: 285 MDGKTPIDVAKLNNQDEVLKLLEK 214 DGK P+ + + E ++LL K Sbjct: 179 QDGKRPLHLCRGPGILECVELLLK 202
>ANR11_HUMAN (Q6UB99) Ankyrin repeat domain-containing protein 11 (Ankyrin| repeat-containing cofactor 1) Length = 2664 Score = 73.9 bits (180), Expect = 4e-13 Identities = 46/120 (38%), Positives = 64/120 (53%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMD 385 +H A GD +K+ + GAD + +D G ALH AC G + A+ LL AGA V+ Sbjct: 173 LHRAAIRGDARRIKELISEGADVNVKDFAGWTALHEACNRGYYDVAKQLLAAGAEVNTKG 232 Query: 384 KNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLLEKDVF 205 + +TPLH AA G + V LLL++G N G+TP+ VA N+ V LL K + Sbjct: 233 LDDDTPLHDAANNGHYKVVKLLLRYGGNPQQSNRKGETPLKVA--NSPTMVNLLLGKGTY 290 Score = 43.5 bits (101), Expect = 6e-04 Identities = 34/115 (29%), Positives = 51/115 (44%), Gaps = 1/115 (0%) Frame = -1 Query: 561 HHTASVGDGEGLKKALDGGADK-DEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMD 385 H + S +G + DK ++ + G LH A G+ + + L+ GA V+ D Sbjct: 140 HPSQSTVCQKGTPNSASKTKDKVNKRNERGETRLHRAAIRGDARRIKELISEGADVNVKD 199 Query: 384 KNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 T LH A G + LL GA V + +D TP+ A N +V+KLL Sbjct: 200 FAGWTALHEACNRGYYDVAKQLLAAGAEVNTKGLDDDTPLHDAANNGHYKVVKLL 254
>CSKI2_HUMAN (Q8WXE0) Caskin-2| Length = 1202 Score = 73.9 bits (180), Expect = 4e-13 Identities = 45/117 (38%), Positives = 63/117 (53%) Frame = -1 Query: 570 SIVHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDA 391 S +HH A G E + L+ A D +DS G R LH+A G + +LL A AAV+A Sbjct: 51 SALHHAALGGSLELIALLLEAQATVDIKDSNGMRPLHYAAWQGRLEPVRLLLRASAAVNA 110 Query: 390 MDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 + PLH AA YG E ++LL+H + L N KTP+D+A + +V +LL Sbjct: 111 ASLDGQIPLHLAAQYGHYEVSEMLLQHQSNPCLVNKAKKTPLDLACEFGRLKVAQLL 167 Score = 68.2 bits (165), Expect = 2e-11 Identities = 39/90 (43%), Positives = 52/90 (57%) Frame = -1 Query: 489 EDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLLKH 310 +D++G ALH A G + +LLEA A VD D N PLHYAA GR E V LLL+ Sbjct: 45 QDADGFSALHHAALGGSLELIALLLEAQATVDIKDSNGMRPLHYAAWQGRLEPVRLLLRA 104 Query: 309 GAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 AAV ++DG+ P+ +A EV ++L Sbjct: 105 SAAVNAASLDGQIPLHLAAQYGHYEVSEML 134 Score = 52.4 bits (124), Expect = 1e-06 Identities = 36/123 (29%), Positives = 58/123 (47%), Gaps = 8/123 (6%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMD 385 +H+ A G E ++ L A + +G+ LH A YG ++ +E+LL+ + ++ Sbjct: 86 LHYAAWQGRLEPVRLLLRASAAVNAASLDGQIPLHLAAQYGHYEVSEMLLQHQSNPCLVN 145 Query: 384 KNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGK--------TPIDVAKLNNQDEVL 229 K K TPL A +GR + LLL V L + K TP+ +A N EV+ Sbjct: 146 KAKKTPLDLACEFGRLKVAQLLLNSHLCVALLEGEAKDPCDPNYTTPLHLAAKNGHREVI 205 Query: 228 KLL 220 + L Sbjct: 206 RQL 208 Score = 47.0 bits (110), Expect = 5e-05 Identities = 32/87 (36%), Positives = 42/87 (48%) Frame = -1 Query: 519 ALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGR 340 AL G KD D LH A G + LL AG ++ K T LH AA YG+ Sbjct: 175 ALLEGEAKDPCDPNYTTPLHLAAKNGHREVIRQLLRAGIEINRQTKT-GTALHEAALYGK 233 Query: 339 KECVDLLLKHGAAVTLQNMDGKTPIDV 259 E V LLL+ G V ++N +T +D+ Sbjct: 234 TEVVRLLLEGGVDVNIRNTYNQTALDI 260 Score = 31.6 bits (70), Expect = 2.2 Identities = 19/60 (31%), Positives = 33/60 (55%) Frame = -1 Query: 399 VDAMDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 V+ D + + LH+AA G E + LLL+ A V +++ +G P+ A + E ++LL Sbjct: 42 VNYQDADGFSALHHAALGGSLELIALLLEAQATVDIKDSNGMRPLHYAAWQGRLEPVRLL 101
>ASB10_HUMAN (Q8WXI3) Ankyrin repeat and SOCS box protein 10 (ASB-10)| Length = 429 Score = 73.9 bits (180), Expect = 4e-13 Identities = 40/101 (39%), Positives = 55/101 (54%), Gaps = 1/101 (0%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAM- 388 +H + G + L GAD + D +G+R LH G G +CAE+LL GA VD Sbjct: 152 LHEACAAGHTACVHVLLVAGADPNIADQDGKRPLHLCRGPGTLECAELLLRFGARVDGRS 211 Query: 387 DKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPI 265 ++ + TPLH AA G E DLLL+ GA +N +G TP+ Sbjct: 212 EEEEETPLHVAARLGHVELADLLLRRGACPDARNAEGWTPL 252 Score = 63.2 bits (152), Expect = 7e-10 Identities = 44/116 (37%), Positives = 56/116 (48%), Gaps = 1/116 (0%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMD 385 +H AS G E L+ L A D GR ALH AC G C +LL AGA + D Sbjct: 120 LHVAASRGHTEVLRLLLRRRARPDSAPG-GRTALHEACAAGHTACVHVLLVAGADPNIAD 178 Query: 384 KNKNTPLHYAAGYGRKECVDLLLKHGAAVT-LQNMDGKTPIDVAKLNNQDEVLKLL 220 ++ PLH G G EC +LLL+ GA V + +TP+ VA E+ LL Sbjct: 179 QDGKRPLHLCRGPGTLECAELLLRFGARVDGRSEEEEETPLHVAARLGHVELADLL 234 Score = 50.4 bits (119), Expect = 5e-06 Identities = 29/78 (37%), Positives = 36/78 (46%), Gaps = 7/78 (8%) Frame = -1 Query: 516 LDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLH-------Y 358 L GAD D D + +R LH AC G E+LL G + + MD +TPLH Sbjct: 281 LSAGADADAADQDKQRPLHLACRRGHAAVVELLLSCGVSANTMDYGGHTPLHCALQGPAA 340 Query: 357 AAGYGRKECVDLLLKHGA 304 A + V LL HGA Sbjct: 341 ALAQSPEHVVRALLNHGA 358 Score = 49.3 bits (116), Expect = 1e-05 Identities = 38/119 (31%), Positives = 50/119 (42%), Gaps = 16/119 (13%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEI------------ 421 +H A +G E L GA D ++EG L AC + +C I Sbjct: 219 LHVAARLGHVELADLLLRRGACPDARNAEGWTPLLAAC---DVRCQSITDAEATTARCLQ 275 Query: 420 ----LLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVA 256 LL AGA DA D++K PLH A G V+LLL G + + G TP+ A Sbjct: 276 LCSLLLSAGADADAADQDKQRPLHLACRRGHAAVVELLLSCGVSANTMDYGGHTPLHCA 334
>RIPK4_HUMAN (P57078) Receptor-interacting serine/threonine-protein kinase 4 (EC| 2.7.11.1) (Ankyrin repeat domain protein 3) (PKC-delta-interacting protein kinase) Length = 832 Score = 73.2 bits (178), Expect = 7e-13 Identities = 42/116 (36%), Positives = 57/116 (49%), Gaps = 1/116 (0%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMD 385 +H A GD + L+ A +E D EGR +H AC +G+ ILL G V Sbjct: 556 LHFAAQNGDESSTRLLLEKNASVNEVDFEGRTPMHVACQHGQENIVRILLRRGVDVSLQG 615 Query: 384 KNKNTPLHYAAGYGRKECVDLLLKH-GAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 K+ PLHYAA G V LL K G +V Q +DG+TP+ +A V ++L Sbjct: 616 KDAWLPLHYAAWQGHLPIVKLLAKQPGVSVNAQTLDGRTPLHLAAQRGHYRVARIL 671 Score = 59.7 bits (143), Expect = 8e-09 Identities = 32/92 (34%), Positives = 49/92 (53%) Frame = -1 Query: 489 EDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLLKH 310 +D + ALHFA G+ +LLE A+V+ +D TP+H A +G++ V +LL+ Sbjct: 548 KDEDQWTALHFAAQNGDESSTRLLLEKNASVNEVDFEGRTPMHVACQHGQENIVRILLRR 607 Query: 309 GAAVTLQNMDGKTPIDVAKLNNQDEVLKLLEK 214 G V+LQ D P+ A ++KLL K Sbjct: 608 GVDVSLQGKDAWLPLHYAAWQGHLPIVKLLAK 639 Score = 56.6 bits (135), Expect = 6e-08 Identities = 35/117 (29%), Positives = 60/117 (51%) Frame = -1 Query: 570 SIVHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDA 391 S++H G E K L A+ + + G LH A E+LL +V+A Sbjct: 488 SLLHLAVEAGQEECAKWLLLNNANPNLSNRRGSTPLHMAVERRVRGVVELLLARKISVNA 547 Query: 390 MDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 D+++ T LH+AA G + LLL+ A+V + +G+TP+ VA + Q+ ++++L Sbjct: 548 KDEDQWTALHFAAQNGDESSTRLLLEKNASVNEVDFEGRTPMHVACQHGQENIVRIL 604 Score = 52.0 bits (123), Expect = 2e-06 Identities = 31/99 (31%), Positives = 45/99 (45%) Frame = -1 Query: 507 GADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECV 328 G + + +GR LH A G ++ A IL++ + V+ TPLH AA G Sbjct: 642 GVSVNAQTLDGRTPLHLAAQRGHYRVARILIDLCSDVNVCSLLAQTPLHVAAETGHTSTA 701 Query: 327 DLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLLEKD 211 LLL GA DG T + +A N +KLL ++ Sbjct: 702 RLLLHRGAGKEAMTSDGYTALHLAARNGHLATVKLLVEE 740 Score = 44.7 bits (104), Expect = 3e-04 Identities = 28/83 (33%), Positives = 38/83 (45%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMD 385 +H A G + L GA K+ S+G ALH A G ++L+E A V A Sbjct: 689 LHVAAETGHTSTARLLLHRGAGKEAMTSDGYTALHLAARNGHLATVKLLVEEKADVLARG 748 Query: 384 KNKNTPLHYAAGYGRKECVDLLL 316 T LH AA +G E V+ L+ Sbjct: 749 PLNQTALHLAAAHGHSEVVEELV 771 Score = 42.0 bits (97), Expect = 0.002 Identities = 33/108 (30%), Positives = 48/108 (44%) Frame = -1 Query: 543 GDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPL 364 GD L K L D D G LH A G+ +CA+ LL A + ++ +TPL Sbjct: 465 GDTSKLMKILQP-QDVDLALDSGASLLHLAVEAGQEECAKWLLLNNANPNLSNRRGSTPL 523 Query: 363 HYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 H A + V+LLL +V ++ D T + A N + +LL Sbjct: 524 HMAVERRVRGVVELLLARKISVNAKDEDQWTALHFAAQNGDESSTRLL 571
>CSKI2_MOUSE (Q8VHK1) Caskin-2| Length = 1201 Score = 73.2 bits (178), Expect = 7e-13 Identities = 45/117 (38%), Positives = 63/117 (53%) Frame = -1 Query: 570 SIVHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDA 391 S +HH A G E + L+ A D +DS G R LH+A G + +LL A AAV+A Sbjct: 51 SALHHAALGGSLELIALLLEAQATVDIKDSNGMRPLHYAAWQGRLEPVRLLLRASAAVNA 110 Query: 390 MDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 + PLH AA YG E ++LL+H + L N KTP+D+A + +V +LL Sbjct: 111 ASLDGQIPLHLAAQYGHYEVSEMLLQHQSNPCLVNKLKKTPLDLACEFGRLKVAQLL 167 Score = 68.2 bits (165), Expect = 2e-11 Identities = 39/90 (43%), Positives = 52/90 (57%) Frame = -1 Query: 489 EDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLLKH 310 +D++G ALH A G + +LLEA A VD D N PLHYAA GR E V LLL+ Sbjct: 45 QDADGFSALHHAALGGSLELIALLLEAQATVDIKDSNGMRPLHYAAWQGRLEPVRLLLRA 104 Query: 309 GAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 AAV ++DG+ P+ +A EV ++L Sbjct: 105 SAAVNAASLDGQIPLHLAAQYGHYEVSEML 134 Score = 52.8 bits (125), Expect = 9e-07 Identities = 37/125 (29%), Positives = 59/125 (47%), Gaps = 8/125 (6%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMD 385 +H+ A G E ++ L A + +G+ LH A YG ++ +E+LL+ + ++ Sbjct: 86 LHYAAWQGRLEPVRLLLRASAAVNAASLDGQIPLHLAAQYGHYEVSEMLLQHQSNPCLVN 145 Query: 384 KNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGK--------TPIDVAKLNNQDEVL 229 K K TPL A +GR + LLL V L + K TP+ +A N EV+ Sbjct: 146 KLKKTPLDLACEFGRLKVAQLLLNSHLCVALLEGEAKDPCDPNYTTPLHLAAKNGHREVI 205 Query: 228 KLLEK 214 + L K Sbjct: 206 RQLLK 210 Score = 52.4 bits (124), Expect = 1e-06 Identities = 34/90 (37%), Positives = 45/90 (50%), Gaps = 8/90 (8%) Frame = -1 Query: 465 LHFACGYGEFKCAEILLEA--------GAAVDAMDKNKNTPLHYAAGYGRKECVDLLLKH 310 L AC +G K A++LL + G A D D N TPLH AA G +E + LLK Sbjct: 152 LDLACEFGRLKVAQLLLNSHLCVALLEGEAKDPCDPNYTTPLHLAAKNGHREVIRQLLKA 211 Query: 309 GAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 G + Q G T + A L + EV++LL Sbjct: 212 GIEINRQTKTG-TALHEAALYGKTEVVRLL 240 Score = 47.4 bits (111), Expect = 4e-05 Identities = 32/87 (36%), Positives = 43/87 (49%) Frame = -1 Query: 519 ALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGR 340 AL G KD D LH A G + LL+AG ++ K T LH AA YG+ Sbjct: 175 ALLEGEAKDPCDPNYTTPLHLAAKNGHREVIRQLLKAGIEINRQTKT-GTALHEAALYGK 233 Query: 339 KECVDLLLKHGAAVTLQNMDGKTPIDV 259 E V LLL+ G V ++N +T +D+ Sbjct: 234 TEVVRLLLEGGVDVNIRNTYNQTALDI 260 Score = 31.2 bits (69), Expect = 2.9 Identities = 18/60 (30%), Positives = 33/60 (55%) Frame = -1 Query: 399 VDAMDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 ++ D + + LH+AA G E + LLL+ A V +++ +G P+ A + E ++LL Sbjct: 42 INYQDADGFSALHHAALGGSLELIALLLEAQATVDIKDSNGMRPLHYAAWQGRLEPVRLL 101
>BARD1_RAT (Q9QZH2) BRCA1-associated RING domain protein 1 (BARD-1)| Length = 768 Score = 71.6 bits (174), Expect = 2e-12 Identities = 42/116 (36%), Positives = 61/116 (52%), Gaps = 1/116 (0%) Frame = -1 Query: 558 HTASV-GDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDK 382 H AS+ GD ++ L G D + +D G LH AC +G K E+LL+ A V+ Sbjct: 423 HIASIKGDISSVEYLLQNGNDPNVKDHAGWTPLHEACSHGHLKIVELLLQHNALVNTTGY 482 Query: 381 NKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLLEK 214 + ++PLH AA G + V +LL HGA+ N+ G+ P+D N +L L EK Sbjct: 483 HNDSPLHDAAKNGHIDIVKVLLSHGASRNAVNIFGERPVDYTDAENIRSLLLLPEK 538 Score = 51.6 bits (122), Expect = 2e-06 Identities = 30/99 (30%), Positives = 45/99 (45%) Frame = -1 Query: 516 LDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRK 337 L G + + G LH A G+ E LL+ G + D TPLH A +G Sbjct: 405 LSSGIPARKRNHRGETLLHIASIKGDISSVEYLLQNGNDPNVKDHAGWTPLHEACSHGHL 464 Query: 336 ECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 + V+LLL+H A V +P+ A N +++K+L Sbjct: 465 KIVELLLQHNALVNTTGYHNDSPLHDAAKNGHIDIVKVL 503
>CSKI2_XENLA (Q6DD51) Caskin-2| Length = 1205 Score = 70.5 bits (171), Expect = 4e-12 Identities = 43/117 (36%), Positives = 63/117 (53%) Frame = -1 Query: 570 SIVHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDA 391 S +HH A G+ E L L+ A D +D G R LH+A G+ + +LL A A+V+A Sbjct: 51 SALHHAALSGNSELLLLLLEMQASVDIKDGNGMRPLHYAAWQGQPEPVRLLLRASASVNA 110 Query: 390 MDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 + PLH AA YG E + LL+H + N KTP+D+A + +V++LL Sbjct: 111 ASHDGQIPLHLAAQYGHYEVSETLLQHQSNPCHVNKGKKTPLDLACEFGRVKVVQLL 167 Score = 60.1 bits (144), Expect = 6e-09 Identities = 36/92 (39%), Positives = 51/92 (55%) Frame = -1 Query: 495 DEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLL 316 + +D++G ALH A G + +LLE A+VD D N PLHYAA G+ E V LLL Sbjct: 43 NHQDADGFSALHHAALSGNSELLLLLLEMQASVDIKDGNGMRPLHYAAWQGQPEPVRLLL 102 Query: 315 KHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 + A+V + DG+ P+ +A EV + L Sbjct: 103 RASASVNAASHDGQIPLHLAAQYGHYEVSETL 134 Score = 57.8 bits (138), Expect = 3e-08 Identities = 39/125 (31%), Positives = 60/125 (48%), Gaps = 8/125 (6%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMD 385 +H+ A G E ++ L A + +G+ LH A YG ++ +E LL+ + ++ Sbjct: 86 LHYAAWQGQPEPVRLLLRASASVNAASHDGQIPLHLAAQYGHYEVSETLLQHQSNPCHVN 145 Query: 384 KNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGK--------TPIDVAKLNNQDEVL 229 K K TPL A +GR + V LLL V+L K TP+ +A N EV+ Sbjct: 146 KGKKTPLDLACEFGRVKVVQLLLNSHLCVSLLEGTSKDPTDPNFTTPLHLAAKNGHLEVI 205 Query: 228 KLLEK 214 +LL K Sbjct: 206 RLLLK 210 Score = 48.1 bits (113), Expect = 2e-05 Identities = 38/123 (30%), Positives = 54/123 (43%), Gaps = 8/123 (6%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEA-------- 409 +H A G E + L ++ + + L AC +G K ++LL + Sbjct: 119 LHLAAQYGHYEVSETLLQHQSNPCHVNKGKKTPLDLACEFGRVKVVQLLLNSHLCVSLLE 178 Query: 408 GAAVDAMDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVL 229 G + D D N TPLH AA G E + LLLK G + G T + A L + EV+ Sbjct: 179 GTSKDPTDPNFTTPLHLAAKNGHLEVIRLLLKLGIEINKVTKMG-TALHEAALCGKTEVV 237 Query: 228 KLL 220 KLL Sbjct: 238 KLL 240 Score = 33.9 bits (76), Expect = 0.45 Identities = 20/60 (33%), Positives = 34/60 (56%) Frame = -1 Query: 399 VDAMDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 V+ D + + LH+AA G E + LLL+ A+V +++ +G P+ A Q E ++LL Sbjct: 42 VNHQDADGFSALHHAALSGNSELLLLLLEMQASVDIKDGNGMRPLHYAAWQGQPEPVRLL 101
>KRIT1_MOUSE (Q6S5J6) Krev interaction trapped protein 1 (Krev interaction| trapped 1) (Cerebral cavernous malformations 1 protein homolog) Length = 736 Score = 70.1 bits (170), Expect = 6e-12 Identities = 42/121 (34%), Positives = 66/121 (54%), Gaps = 5/121 (4%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAA-VDAM 388 +H A GD E L LD G ++ D++ +H+AC YG+ + ILLE G + + Sbjct: 292 LHRNACEGDSELLSHLLDKGLSVNQLDNDHWAPIHYACWYGKVEATRILLEKGKCNPNLL 351 Query: 387 DKNKNTPLHYAAGYGRKECVDLLLKH-GAAVTLQNMDGKTPIDVA---KLNNQDEVLKLL 220 + ++PLH+AAG G E V +LL H + + G++P++V K NN +E KLL Sbjct: 352 NGQLSSPLHFAAGGGHAEIVQILLTHPDIDRHITDQQGRSPLNVCEENKQNNWEEAAKLL 411 Query: 219 E 217 + Sbjct: 412 K 412
>GABP2_MOUSE (Q00420) GA-binding protein beta chain (GABP-beta-2 subunit)| (GABP-2) (GABP-beta-1 subunit) (GABPB-1) Length = 383 Score = 70.1 bits (170), Expect = 6e-12 Identities = 39/88 (44%), Positives = 49/88 (55%) Frame = -1 Query: 477 GRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLLKHGAAV 298 G LH A YG F E+LL AG + DA K TPLH AA G V++LLKHGA V Sbjct: 38 GTSPLHLAAQYGHFSTTEVLLRAGVSRDARTKVDRTPLHMAASEGHANIVEVLLKHGADV 97 Query: 297 TLQNMDGKTPIDVAKLNNQDEVLKLLEK 214 ++M T + A +N EV++LL K Sbjct: 98 NAKDMLKMTALHWATEHNHQEVVELLIK 125 Score = 67.4 bits (163), Expect = 4e-11 Identities = 39/118 (33%), Positives = 60/118 (50%) Frame = -1 Query: 570 SIVHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDA 391 S +H A G + L G +D R LH A G E+LL+ GA V+A Sbjct: 40 SPLHLAAQYGHFSTTEVLLRAGVSRDARTKVDRTPLHMAASEGHANIVEVLLKHGADVNA 99 Query: 390 MDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLLE 217 D K T LH+A + +E V+LL+K+GA V Q+ KT D++ N +++ ++L+ Sbjct: 100 KDMLKMTALHWATEHNHQEVVELLIKYGADVHTQSKFCKTAFDISIDNGNEDLAEILQ 157 Score = 33.1 bits (74), Expect = 0.77 Identities = 19/69 (27%), Positives = 33/69 (47%) Frame = -1 Query: 420 LLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQ 241 +L A A D +PLH AA YG ++LL+ G + + +TP+ +A Sbjct: 24 ILMANGAPFTTDWLGTSPLHLAAQYGHFSTTEVLLRAGVSRDARTKVDRTPLHMAASEGH 83 Query: 240 DEVLKLLEK 214 ++++L K Sbjct: 84 ANIVEVLLK 92
>CSKI1_MOUSE (Q6P9K8) Caskin-1 (CASK-interacting protein 1)| Length = 1431 Score = 69.7 bits (169), Expect = 7e-12 Identities = 39/117 (33%), Positives = 68/117 (58%) Frame = -1 Query: 570 SIVHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDA 391 S +HH A G+ E + L+ A D +D++G R LH+A G + +++L+AG+AV+ Sbjct: 51 SALHHAALNGNTELISLLLEAQAAVDIKDNKGMRPLHYAAWQGRKEPMKLVLKAGSAVNV 110 Query: 390 MDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 + PLH AA +G + ++LL+H + + + GKTP+D+A + V++LL Sbjct: 111 PSDEGHIPLHLAAQHGHYDVSEMLLQHQSNPCMVDNSGKTPLDLACEFGRVGVVQLL 167 Score = 66.2 bits (160), Expect = 8e-11 Identities = 37/90 (41%), Positives = 53/90 (58%) Frame = -1 Query: 489 EDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLLKH 310 +D +G ALH A G + +LLEA AAVD D PLHYAA GRKE + L+LK Sbjct: 45 QDPDGFSALHHAALNGNTELISLLLEAQAAVDIKDNKGMRPLHYAAWQGRKEPMKLVLKA 104 Query: 309 GAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 G+AV + + +G P+ +A + +V ++L Sbjct: 105 GSAVNVPSDEGHIPLHLAAQHGHYDVSEML 134 Score = 52.8 bits (125), Expect = 9e-07 Identities = 34/123 (27%), Positives = 57/123 (46%), Gaps = 8/123 (6%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMD 385 +H+ A G E +K L G+ + EG LH A +G + +E+LL+ + +D Sbjct: 86 LHYAAWQGRKEPMKLVLKAGSAVNVPSDEGHIPLHLAAQHGHYDVSEMLLQHQSNPCMVD 145 Query: 384 KNKNTPLHYAAGYGRKECVDLLLKHGAAVTL--------QNMDGKTPIDVAKLNNQDEVL 229 + TPL A +GR V LLL L + +G +P+ +A N +++ Sbjct: 146 NSGKTPLDLACEFGRVGVVQLLLSSNMCAALLEPRPGDTTDPNGTSPLHLAAKNGHIDII 205 Query: 228 KLL 220 +LL Sbjct: 206 RLL 208 Score = 45.8 bits (107), Expect = 1e-04 Identities = 30/97 (30%), Positives = 45/97 (46%), Gaps = 8/97 (8%) Frame = -1 Query: 486 DSEGRRALHFACGYGEFKCAEILLEAGAAV--------DAMDKNKNTPLHYAAGYGRKEC 331 D+ G+ L AC +G ++LL + D D N +PLH AA G + Sbjct: 145 DNSGKTPLDLACEFGRVGVVQLLLSSNMCAALLEPRPGDTTDPNGTSPLHLAAKNGHIDI 204 Query: 330 VDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 + LLL+ G + Q G T + A L + EV++LL Sbjct: 205 IRLLLQAGIDINRQTKSG-TALHEAALCGKTEVVRLL 240 Score = 44.3 bits (103), Expect = 3e-04 Identities = 27/79 (34%), Positives = 38/79 (48%) Frame = -1 Query: 495 DEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLL 316 D D G LH A G +LL+AG ++ K+ T LH AA G+ E V LLL Sbjct: 183 DTTDPNGTSPLHLAAKNGHIDIIRLLLQAGIDINRQTKS-GTALHEAALCGKTEVVRLLL 241 Query: 315 KHGAAVTLQNMDGKTPIDV 259 G ++N +T +D+ Sbjct: 242 DSGINAQVRNTYSQTALDI 260 Score = 36.2 bits (82), Expect = 0.091 Identities = 21/62 (33%), Positives = 34/62 (54%) Frame = -1 Query: 399 VDAMDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 V+ D + + LH+AA G E + LLL+ AAV +++ G P+ A + E +KL+ Sbjct: 42 VNFQDPDGFSALHHAALNGNTELISLLLEAQAAVDIKDNKGMRPLHYAAWQGRKEPMKLV 101 Query: 219 EK 214 K Sbjct: 102 LK 103
>CSKI1_RAT (Q8VHK2) Caskin-1 (CASK-interacting protein 1)| Length = 1430 Score = 69.7 bits (169), Expect = 7e-12 Identities = 39/117 (33%), Positives = 68/117 (58%) Frame = -1 Query: 570 SIVHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDA 391 S +HH A G+ E + L+ A D +D++G R LH+A G + +++L+AG+AV+ Sbjct: 51 SALHHAALNGNTELISLLLEAQAAVDIKDNKGMRPLHYAAWQGRKEPMKLVLKAGSAVNV 110 Query: 390 MDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 + PLH AA +G + ++LL+H + + + GKTP+D+A + V++LL Sbjct: 111 PSDEGHIPLHLAAQHGHYDVSEMLLQHQSNPCIVDNSGKTPLDLACEFGRVGVVQLL 167 Score = 66.2 bits (160), Expect = 8e-11 Identities = 37/90 (41%), Positives = 53/90 (58%) Frame = -1 Query: 489 EDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLLKH 310 +D +G ALH A G + +LLEA AAVD D PLHYAA GRKE + L+LK Sbjct: 45 QDPDGFSALHHAALNGNTELISLLLEAQAAVDIKDNKGMRPLHYAAWQGRKEPMKLVLKA 104 Query: 309 GAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 G+AV + + +G P+ +A + +V ++L Sbjct: 105 GSAVNVPSDEGHIPLHLAAQHGHYDVSEML 134 Score = 52.8 bits (125), Expect = 9e-07 Identities = 34/123 (27%), Positives = 57/123 (46%), Gaps = 8/123 (6%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMD 385 +H+ A G E +K L G+ + EG LH A +G + +E+LL+ + +D Sbjct: 86 LHYAAWQGRKEPMKLVLKAGSAVNVPSDEGHIPLHLAAQHGHYDVSEMLLQHQSNPCIVD 145 Query: 384 KNKNTPLHYAAGYGRKECVDLLLKHGAAVTL--------QNMDGKTPIDVAKLNNQDEVL 229 + TPL A +GR V LLL L + +G +P+ +A N +++ Sbjct: 146 NSGKTPLDLACEFGRVGVVQLLLSSNMCAALLEPRPGDTTDPNGTSPLHLAAKNGHIDII 205 Query: 228 KLL 220 +LL Sbjct: 206 RLL 208 Score = 45.8 bits (107), Expect = 1e-04 Identities = 30/97 (30%), Positives = 45/97 (46%), Gaps = 8/97 (8%) Frame = -1 Query: 486 DSEGRRALHFACGYGEFKCAEILLEAGAAV--------DAMDKNKNTPLHYAAGYGRKEC 331 D+ G+ L AC +G ++LL + D D N +PLH AA G + Sbjct: 145 DNSGKTPLDLACEFGRVGVVQLLLSSNMCAALLEPRPGDTTDPNGTSPLHLAAKNGHIDI 204 Query: 330 VDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 + LLL+ G + Q G T + A L + EV++LL Sbjct: 205 IRLLLQAGIDINRQTKSG-TALHEAALCGKTEVVRLL 240 Score = 44.3 bits (103), Expect = 3e-04 Identities = 27/79 (34%), Positives = 38/79 (48%) Frame = -1 Query: 495 DEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLL 316 D D G LH A G +LL+AG ++ K+ T LH AA G+ E V LLL Sbjct: 183 DTTDPNGTSPLHLAAKNGHIDIIRLLLQAGIDINRQTKS-GTALHEAALCGKTEVVRLLL 241 Query: 315 KHGAAVTLQNMDGKTPIDV 259 G ++N +T +D+ Sbjct: 242 DSGINAQVRNTYSQTALDI 260 Score = 36.2 bits (82), Expect = 0.091 Identities = 21/62 (33%), Positives = 34/62 (54%) Frame = -1 Query: 399 VDAMDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 V+ D + + LH+AA G E + LLL+ AAV +++ G P+ A + E +KL+ Sbjct: 42 VNFQDPDGFSALHHAALNGNTELISLLLEAQAAVDIKDNKGMRPLHYAAWQGRKEPMKLV 101 Query: 219 EK 214 K Sbjct: 102 LK 103
>CSKI1_HUMAN (Q8WXD9) Caskin-1 (CASK-interacting protein 1)| Length = 1431 Score = 69.3 bits (168), Expect = 1e-11 Identities = 39/117 (33%), Positives = 68/117 (58%) Frame = -1 Query: 570 SIVHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDA 391 S +HH A G+ E + L+ A D +D++G R LH+A G + +++L+AG+AV+ Sbjct: 51 SALHHAALNGNTELISLLLEAQAAVDIKDNKGMRPLHYAAWQGRKEPMKLVLKAGSAVNI 110 Query: 390 MDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 + PLH AA +G + ++LL+H + + + GKTP+D+A + V++LL Sbjct: 111 PSDEGHIPLHLAAQHGHYDVSEMLLQHQSNPCMVDNSGKTPLDLACEFGRVGVVQLL 167 Score = 66.6 bits (161), Expect = 6e-11 Identities = 37/90 (41%), Positives = 53/90 (58%) Frame = -1 Query: 489 EDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLLKH 310 +D +G ALH A G + +LLEA AAVD D PLHYAA GRKE + L+LK Sbjct: 45 QDPDGFSALHHAALNGNTELISLLLEAQAAVDIKDNKGMRPLHYAAWQGRKEPMKLVLKA 104 Query: 309 GAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 G+AV + + +G P+ +A + +V ++L Sbjct: 105 GSAVNIPSDEGHIPLHLAAQHGHYDVSEML 134 Score = 52.4 bits (124), Expect = 1e-06 Identities = 34/123 (27%), Positives = 57/123 (46%), Gaps = 8/123 (6%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMD 385 +H+ A G E +K L G+ + EG LH A +G + +E+LL+ + +D Sbjct: 86 LHYAAWQGRKEPMKLVLKAGSAVNIPSDEGHIPLHLAAQHGHYDVSEMLLQHQSNPCMVD 145 Query: 384 KNKNTPLHYAAGYGRKECVDLLLKHGAAVTL--------QNMDGKTPIDVAKLNNQDEVL 229 + TPL A +GR V LLL L + +G +P+ +A N +++ Sbjct: 146 NSGKTPLDLACEFGRVGVVQLLLSSNMCAALLEPRPGDATDPNGTSPLHLAAKNGHIDII 205 Query: 228 KLL 220 +LL Sbjct: 206 RLL 208 Score = 47.4 bits (111), Expect = 4e-05 Identities = 31/97 (31%), Positives = 46/97 (47%), Gaps = 8/97 (8%) Frame = -1 Query: 486 DSEGRRALHFACGYGEFKCAEILLEAGAAV--------DAMDKNKNTPLHYAAGYGRKEC 331 D+ G+ L AC +G ++LL + DA D N +PLH AA G + Sbjct: 145 DNSGKTPLDLACEFGRVGVVQLLLSSNMCAALLEPRPGDATDPNGTSPLHLAAKNGHIDI 204 Query: 330 VDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 + LLL+ G + Q G T + A L + EV++LL Sbjct: 205 IRLLLQAGIDINRQTKSG-TALHEAALCGKTEVVRLL 240 Score = 43.9 bits (102), Expect = 4e-04 Identities = 27/79 (34%), Positives = 38/79 (48%) Frame = -1 Query: 495 DEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLL 316 D D G LH A G +LL+AG ++ K+ T LH AA G+ E V LLL Sbjct: 183 DATDPNGTSPLHLAAKNGHIDIIRLLLQAGIDINRQTKS-GTALHEAALCGKTEVVRLLL 241 Query: 315 KHGAAVTLQNMDGKTPIDV 259 G ++N +T +D+ Sbjct: 242 DSGINAHVRNTYSQTALDI 260 Score = 36.2 bits (82), Expect = 0.091 Identities = 21/62 (33%), Positives = 34/62 (54%) Frame = -1 Query: 399 VDAMDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 V+ D + + LH+AA G E + LLL+ AAV +++ G P+ A + E +KL+ Sbjct: 42 VNFQDPDGFSALHHAALNGNTELISLLLEAQAAVDIKDNKGMRPLHYAAWQGRKEPMKLV 101 Query: 219 EK 214 K Sbjct: 102 LK 103
>GABP2_HUMAN (Q06547) GA-binding protein beta chain (GABP-beta-2 subunit)| (GABP-2) (GABP-beta-1 subunit) (GABPB-1) (Transcription factor E4TF1-53) (Transcription factor E4TF1-47) (Nuclear respiratory factor 2) Length = 395 Score = 68.9 bits (167), Expect = 1e-11 Identities = 38/88 (43%), Positives = 49/88 (55%) Frame = -1 Query: 477 GRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLLKHGAAV 298 G LH A YG + E+LL AG + DA K TPLH AA G V++LLKHGA V Sbjct: 38 GTSPLHLAAQYGHYSTTEVLLRAGVSRDARTKVDRTPLHMAASEGHASIVEVLLKHGADV 97 Query: 297 TLQNMDGKTPIDVAKLNNQDEVLKLLEK 214 ++M T + A +N EV++LL K Sbjct: 98 NAKDMLKMTALHWATEHNHQEVVELLIK 125 Score = 67.4 bits (163), Expect = 4e-11 Identities = 39/118 (33%), Positives = 60/118 (50%) Frame = -1 Query: 570 SIVHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDA 391 S +H A G + L G +D R LH A G E+LL+ GA V+A Sbjct: 40 SPLHLAAQYGHYSTTEVLLRAGVSRDARTKVDRTPLHMAASEGHASIVEVLLKHGADVNA 99 Query: 390 MDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLLE 217 D K T LH+A + +E V+LL+K+GA V Q+ KT D++ N +++ ++L+ Sbjct: 100 KDMLKMTALHWATEHNHQEVVELLIKYGADVHTQSKFCKTAFDISIDNGNEDLAEILQ 157 Score = 33.5 bits (75), Expect = 0.59 Identities = 19/69 (27%), Positives = 33/69 (47%) Frame = -1 Query: 420 LLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQ 241 +L A A D +PLH AA YG ++LL+ G + + +TP+ +A Sbjct: 24 ILMANGAPFTTDWLGTSPLHLAAQYGHYSTTEVLLRAGVSRDARTKVDRTPLHMAASEGH 83 Query: 240 DEVLKLLEK 214 ++++L K Sbjct: 84 ASIVEVLLK 92
>KRIT1_HUMAN (O00522) Krev interaction trapped protein 1 (Krev interaction| trapped 1) (Cerebral cavernous malformations 1 protein) Length = 736 Score = 68.6 bits (166), Expect = 2e-11 Identities = 40/124 (32%), Positives = 68/124 (54%), Gaps = 5/124 (4%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAA-VDAM 388 +H +A GD E L + L ++ DS+ +H+AC YG+ + ILLE G + + Sbjct: 292 LHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNLL 351 Query: 387 DKNKNTPLHYAAGYGRKECVDLLLKHGAAVT-LQNMDGKTPIDVA---KLNNQDEVLKLL 220 + ++PLH+AAG G E V +LL H + + G++P+++ K NN +E KLL Sbjct: 352 NGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNICEENKQNNWEEAAKLL 411 Query: 219 EKDV 208 ++ + Sbjct: 412 KEAI 415
>KRIT1_BOVIN (Q6TNJ1) Krev interaction trapped protein 1 (Krev interaction| trapped 1) (Cerebral cavernous malformations 1 protein homolog) Length = 736 Score = 68.6 bits (166), Expect = 2e-11 Identities = 40/124 (32%), Positives = 69/124 (55%), Gaps = 5/124 (4%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAA-VDAM 388 +H +A GD E L + L+ ++ DS+ +H+AC YG+ + ILLE G + + Sbjct: 292 LHRSACEGDSELLNRLLNERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNLL 351 Query: 387 DKNKNTPLHYAAGYGRKECVDLLLKHGAAVT-LQNMDGKTPIDVA---KLNNQDEVLKLL 220 + ++PLH+AAG G E V +LL H + + G++P+++ K NN +E KLL Sbjct: 352 NGQLSSPLHFAAGGGHAEIVQILLNHPEIDRHITDQQGRSPLNICEENKQNNWEEAAKLL 411 Query: 219 EKDV 208 ++ + Sbjct: 412 KEAI 415
>BARD1_HUMAN (Q99728) BRCA1-associated RING domain protein 1 (BARD-1)| Length = 777 Score = 68.2 bits (165), Expect = 2e-11 Identities = 41/117 (35%), Positives = 61/117 (52%), Gaps = 1/117 (0%) Frame = -1 Query: 558 HTASV-GDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDK 382 H AS+ GD ++ L G+D + +D G LH AC +G K E+LL+ A V+ Sbjct: 433 HIASIKGDIPSVEYLLQNGSDPNVKDHAGWTPLHEACNHGHLKVVELLLQHKALVNTTGY 492 Query: 381 NKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLLEKD 211 ++PLH AA G + V LLL +GA+ N+ G P+D + +L L EK+ Sbjct: 493 QNDSPLHDAAKNGHVDIVKLLLSYGASRNAVNIFGLRPVDYTDDESMKSLLLLPEKN 549 Score = 51.2 bits (121), Expect = 3e-06 Identities = 29/91 (31%), Positives = 44/91 (48%) Frame = -1 Query: 492 EEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLLK 313 + + G LH A G+ E LL+ G+ + D TPLH A +G + V+LLL+ Sbjct: 423 KRNHRGETLLHIASIKGDIPSVEYLLQNGSDPNVKDHAGWTPLHEACNHGHLKVVELLLQ 482 Query: 312 HGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 H A V +P+ A N +++KLL Sbjct: 483 HKALVNTTGYQNDSPLHDAAKNGHVDIVKLL 513
>INVS_BRARE (Q8UVC1) Inversin| Length = 1021 Score = 68.2 bits (165), Expect = 2e-11 Identities = 42/119 (35%), Positives = 61/119 (51%) Frame = -1 Query: 570 SIVHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDA 391 S VH A GD L K + A +D ED GR L + CAE+LL+AGA ++ Sbjct: 10 SQVHAAAVNGDKNTLHKLITESALRDSEDQFGRTPLMYCVLADRLDCAEVLLKAGAGINK 69 Query: 390 MDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLLEK 214 D ++ T LH AA G + LLL A L++++ TP+ +A ++ + L LL K Sbjct: 70 TDHSQRTALHLAAQKGNVRFMKLLLSRHADWRLKDLEEMTPLHLASRHSSSKPLSLLLK 128 Score = 60.1 bits (144), Expect = 6e-09 Identities = 42/139 (30%), Positives = 67/139 (48%), Gaps = 14/139 (10%) Frame = -1 Query: 546 VGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTP 367 +G + + + GGA D D +G ALH+A G + E+L+E G + + D+ TP Sbjct: 393 MGHRDVILTLIKGGARVDLVDIDGHSALHWAALGGNAEVCEVLMENGISPNLQDQAGRTP 452 Query: 366 LHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL----------- 220 L AA G C+ LL++H A +Q+ +G+T + + N + +KLL Sbjct: 453 LQCAAYAGYINCMALLIQHDADPNIQDKEGRTALHWSCNNGYLDAVKLLLGCGAFPNHME 512 Query: 219 ---EKDVFL*IASLGSHEE 172 E+ L A LG H+E Sbjct: 513 HTEERYTPLDYALLGEHQE 531 Score = 58.9 bits (141), Expect = 1e-08 Identities = 40/113 (35%), Positives = 55/113 (48%), Gaps = 2/113 (1%) Frame = -1 Query: 552 ASVGDGEGLKKALDGGADKDEE--DSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKN 379 A G + +K LD D D D G ALH A G +LLE G VD +D Sbjct: 323 AGKGSNDVIKIMLDLKKDIDINMTDKYGGTALHAAALSGHVSTVRLLLEQGGMVDPLDVM 382 Query: 378 KNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 K+TPL A G ++ + L+K GA V L ++DG + + A L EV ++L Sbjct: 383 KHTPLFRACEMGHRDVILTLIKGGARVDLVDIDGHSALHWAALGGNAEVCEVL 435 Score = 58.2 bits (139), Expect = 2e-08 Identities = 37/108 (34%), Positives = 54/108 (50%), Gaps = 2/108 (1%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLE--AGAAVDA 391 +H A G+ +K L AD +D E LH A + K +LL+ A VD Sbjct: 78 LHLAAQKGNVRFMKLLLSRHADWRLKDLEEMTPLHLASRHSSSKPLSLLLKHMAPGEVDT 137 Query: 390 MDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLN 247 D+NK T LH++A Y E V LL+KH + + + + +GK P+ A N Sbjct: 138 QDRNKQTALHWSAFYNHPEHVKLLIKHDSNIGIPDSEGKIPLHWAAHN 185 Score = 51.6 bits (122), Expect = 2e-06 Identities = 37/130 (28%), Positives = 62/130 (47%), Gaps = 2/130 (1%) Frame = -1 Query: 570 SIVHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDA 391 S +H A G+ E + ++ G + +D GR L A G C +L++ A + Sbjct: 418 SALHWAALGGNAEVCEVLMENGISPNLQDQAGRTPLQCAAYAGYINCMALLIQHDADPNI 477 Query: 390 MDKNKNTPLHYAAGYGRKECVDLLLKHGAAVT-LQNMDGK-TPIDVAKLNNQDEVLKLLE 217 DK T LH++ G + V LLL GA +++ + + TP+D A L E+ + L Sbjct: 478 QDKEGRTALHWSCNNGYLDAVKLLLGCGAFPNHMEHTEERYTPLDYALLGEHQELTQFLL 537 Query: 216 KDVFL*IASL 187 + L IA++ Sbjct: 538 EHGALSIAAI 547 Score = 50.1 bits (118), Expect = 6e-06 Identities = 31/103 (30%), Positives = 51/103 (49%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMD 385 +H A G ++ L+ G D D L AC G L++ GA VD +D Sbjct: 354 LHAAALSGHVSTVRLLLEQGGMVDPLDVMKHTPLFRACEMGHRDVILTLIKGGARVDLVD 413 Query: 384 KNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVA 256 + ++ LH+AA G E ++L+++G + LQ+ G+TP+ A Sbjct: 414 IDGHSALHWAALGGNAEVCEVLMENGISPNLQDQAGRTPLQCA 456 Score = 45.8 bits (107), Expect = 1e-04 Identities = 30/84 (35%), Positives = 42/84 (50%), Gaps = 2/84 (2%) Frame = -1 Query: 489 EDSEGRRALHFACGYGEFKCAEILLE-AGAAVDAMDKNKNTPLHYAAGYGRKECVDLLL- 316 +D EGR LHFA G E+L G +V A D TPLH+AA G + V LLL Sbjct: 210 QDYEGRTPLHFAVADGNEAVVEVLTSYEGCSVTAYDNLFRTPLHWAALLGHAKIVHLLLE 269 Query: 315 KHGAAVTLQNMDGKTPIDVAKLNN 244 ++ + + + G TP+ +N Sbjct: 270 RNKSGMIPSDSQGATPLHYGAQSN 293 Score = 41.6 bits (96), Expect = 0.002 Identities = 34/123 (27%), Positives = 54/123 (43%), Gaps = 6/123 (4%) Frame = -1 Query: 558 HTASVGDGEGLKKALDG--GADKDEEDSEGRRALHFACGYGEFKCAEILLEAG-AAVDAM 388 H A E + + L G D+ R LH+A G K +LLE + + Sbjct: 219 HFAVADGNEAVVEVLTSYEGCSVTAYDNLFRTPLHWAALLGHAKIVHLLLERNKSGMIPS 278 Query: 387 DKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKL---LE 217 D TPLHY A + V + LKH + +++G+T A ++V+K+ L+ Sbjct: 279 DSQGATPLHYGAQSNFADTVAVFLKHHSVRDEPDLEGRTAFMWAAGKGSNDVIKIMLDLK 338 Query: 216 KDV 208 KD+ Sbjct: 339 KDI 341
>PSD10_HUMAN (O75832) 26S proteasome non-ATPase regulatory subunit 10 (26S| proteasome regulatory subunit p28) (Gankyrin) Length = 226 Score = 68.2 bits (165), Expect = 2e-11 Identities = 39/104 (37%), Positives = 54/104 (51%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMD 385 +H+ AS E L+GGA+ D +D A+H A G K ILL A+ + D Sbjct: 110 LHYAASKNRHEIAVMLLEGGANPDAKDHYEATAMHRAAAKGNLKMIHILLYYKASTNIQD 169 Query: 384 KNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAK 253 NTPLH A R E LL+ GA++ ++N + KTP+ VAK Sbjct: 170 TEGNTPLHLACDEERVEEAKLLVSQGASIYIENKEEKTPLQVAK 213 Score = 66.2 bits (160), Expect = 8e-11 Identities = 45/119 (37%), Positives = 61/119 (51%), Gaps = 3/119 (2%) Frame = -1 Query: 567 IVHHTASVGDGEGLKKALDGGADKD---EEDSEGRRALHFACGYGEFKCAEILLEAGAAV 397 +V + A G E LK+++ ADK D + R ALH+AC G + E LL+ G V Sbjct: 9 MVCNLAYSGKLEELKESIL--ADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQLGVPV 66 Query: 396 DAMDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 + D +PLH AA GR E V LL GA V N +G TP+ A N+ E+ +L Sbjct: 67 NDKDDAGWSPLHIAASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVML 125 Score = 65.1 bits (157), Expect = 2e-10 Identities = 40/117 (34%), Positives = 60/117 (51%) Frame = -1 Query: 570 SIVHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDA 391 S +H AS G E +K L GA + + G LH+A + A +LLE GA DA Sbjct: 75 SPLHIAASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPDA 134 Query: 390 MDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 D + T +H AA G + + +LL + A+ +Q+ +G TP+ +A + E KLL Sbjct: 135 KDHYEATAMHRAAAKGNLKMIHILLYYKASTNIQDTEGNTPLHLACDEERVEEAKLL 191 Score = 55.1 bits (131), Expect = 2e-07 Identities = 32/87 (36%), Positives = 46/87 (52%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMD 385 +H S G E ++ L G +++D G LH A G + + LL GA V+A++ Sbjct: 44 LHWACSAGHTEIVEFLLQLGVPVNDKDDAGWSPLHIAASAGRDEIVKALLGKGAQVNAVN 103 Query: 384 KNKNTPLHYAAGYGRKECVDLLLKHGA 304 +N TPLHYAA R E +LL+ GA Sbjct: 104 QNGCTPLHYAASKNRHEIAVMLLEGGA 130 Score = 39.7 bits (91), Expect = 0.008 Identities = 22/72 (30%), Positives = 38/72 (52%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMD 385 +H A+ G+ + + L A + +D+EG LH AC + A++L+ GA++ + Sbjct: 143 MHRAAAKGNLKMIHILLYYKASTNIQDTEGNTPLHLACDEERVEEAKLLVSQGASIYIEN 202 Query: 384 KNKNTPLHYAAG 349 K + TPL A G Sbjct: 203 KEEKTPLQVAKG 214
>UACA_HUMAN (Q9BZF9) Uveal autoantigen with coiled-coil domains and ankyrin| repeats protein Length = 1416 Score = 68.2 bits (165), Expect = 2e-11 Identities = 40/117 (34%), Positives = 58/117 (49%) Frame = -1 Query: 570 SIVHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDA 391 S+ H S G+ E L L G D D+ GR ALH A YG C + LL+ + Sbjct: 70 SVFHVVTSKGNLECLNAILIHGVDITTSDTAGRNALHLAAKYGHALCLQKLLQYNCPTEH 129 Query: 390 MDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 D T LH AA + LL HGA+V +++DG+TP+ +A ++ + +LL Sbjct: 130 ADLQGRTALHDAAMADCPSSIQLLCDHGASVNAKDVDGRTPLVLATQMSRPTICQLL 186 Score = 46.2 bits (108), Expect = 9e-05 Identities = 30/112 (26%), Positives = 47/112 (41%), Gaps = 1/112 (0%) Frame = -1 Query: 552 ASVGDGEGLKKAL-DGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNK 376 A GD E + L G + + D EGR H G +C +L G + D Sbjct: 42 AERGDVEKVTSILAKKGVNPGKLDVEGRSVFHVVTSKGNLECLNAILIHGVDITTSDTAG 101 Query: 375 NTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 LH AA YG C+ LL++ ++ G+T + A + + ++LL Sbjct: 102 RNALHLAAKYGHALCLQKLLQYNCPTEHADLQGRTALHDAAMADCPSSIQLL 153 Score = 37.7 bits (86), Expect = 0.031 Identities = 18/54 (33%), Positives = 28/54 (51%) Frame = -1 Query: 516 LDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYA 355 +D GAD + D + R AL C YG E+L++ GA + +D + +YA Sbjct: 187 IDRGADVNSRDKQNRTALMLGCEYGCRDAVEVLIKNGADISLLDALGHDSSYYA 240
>LCTA_LATMA (Q9XZC0) Alpha-latrocrustotoxin (Alpha-LCT) (Crusta1)| Length = 1395 Score = 67.8 bits (164), Expect = 3e-11 Identities = 36/115 (31%), Positives = 62/115 (53%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMD 385 +H A+ G+ + +K L+ GA D+E + G ALH A + + L+ GA ++A Sbjct: 720 LHLAAATGNSQIVKTILNSGAVVDQETANGFTALHLAIMNPNTETPQFLIAKGANINAKT 779 Query: 384 KNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 + +TPLH+AA G+ LL+ GA + +N+ + PI A +N ++K+L Sbjct: 780 NDGSTPLHFAAALGKTNIFQLLMDKGANIKAENLINQMPIHEAVVNGHLAIVKML 834 Score = 44.7 bits (104), Expect = 3e-04 Identities = 32/107 (29%), Positives = 54/107 (50%), Gaps = 3/107 (2%) Frame = -1 Query: 525 KKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILL-EAGAAVDAMDKNKNTPLHYAAG 349 +K +D GA GR+++H + G A +LL + ++ DKN TPLH A+ Sbjct: 461 RKLIDSGAQVGASFEMGRKSIHASATAGNDDVARLLLAKNNGLLNVPDKNGYTPLHIASE 520 Query: 348 YGRKECVDLLLKHGAAVTLQNMDGK-TPIDVAKLNNQDEVLK-LLEK 214 + V LL+ GA V ++ + TP+ +A + ++K L+EK Sbjct: 521 RKNNDFVKFLLEKGADVNVRTFANELTPLHLAARQDFTIIVKTLMEK 567 Score = 42.0 bits (97), Expect = 0.002 Identities = 25/98 (25%), Positives = 48/98 (48%), Gaps = 1/98 (1%) Frame = -1 Query: 507 GADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECV 328 GA+ + + ++G LHFA G+ ++L++ GA + A + P+H A G V Sbjct: 772 GANINAKTNDGSTPLHFAAALGKTNIFQLLMDKGANIKAENLINQMPIHEAVVNGHLAIV 831 Query: 327 DLLLKHGAA-VTLQNMDGKTPIDVAKLNNQDEVLKLLE 217 +L++ ++ + +NM + P +A +V LE Sbjct: 832 KMLIEQDSSLMNAKNMRDEYPFYLAAEKRYKDVFNYLE 869 Score = 35.8 bits (81), Expect = 0.12 Identities = 27/92 (29%), Positives = 44/92 (47%), Gaps = 1/92 (1%) Frame = -1 Query: 528 LKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAA-VDAMDKNKNTPLHYAA 352 L + GAD +++ G L A G++ + L+E V+ +K + TPLH AA Sbjct: 1076 LNYLIRNGADPNKK-VRGDPPLFIAAMIGQYDIVKSLVEQHKIDVNTRNKEQFTPLHAAA 1134 Query: 351 GYGRKECVDLLLKHGAAVTLQNMDGKTPIDVA 256 + V L++ GA V + + PID+A Sbjct: 1135 SNDHIDVVKYLIQKGADVNAKGDENLKPIDLA 1166 Score = 34.3 bits (77), Expect = 0.35 Identities = 24/96 (25%), Positives = 38/96 (39%), Gaps = 2/96 (2%) Frame = -1 Query: 507 GADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECV 328 G D + ++ G LH + ++ E A ++ + TPLH A Sbjct: 569 GIDVNAKERAGFTPLHLSITSNSRAARTLINETPAGINIKSNSGLTPLHLAVLQNNLSAA 628 Query: 327 DLLLKHGAAVTLQNMD--GKTPIDVAKLNNQDEVLK 226 +L+K V L MD G TP+ A + E +K Sbjct: 629 KVLVKSNKKVKLNEMDNNGMTPLHYASMLGNLEFVK 664 Score = 33.1 bits (74), Expect = 0.77 Identities = 29/119 (24%), Positives = 52/119 (43%), Gaps = 2/119 (1%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRA-LHFACGYGEFKCAEILLEA-GAAVDA 391 +H + + + +K L+ GAD + LH A + L+E G V+A Sbjct: 515 LHIASERKNNDFVKFLLEKGADVNVRTFANELTPLHLAARQDFTIIVKTLMEKRGIDVNA 574 Query: 390 MDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLLEK 214 ++ TPLH + + L+ + A + +++ G TP+ +A L N K+L K Sbjct: 575 KERAGFTPLHLSITSNSRAARTLINETPAGINIKSNSGLTPLHLAVLQNNLSAAKVLVK 633 Score = 32.7 bits (73), Expect = 1.0 Identities = 19/79 (24%), Positives = 35/79 (44%) Frame = -1 Query: 507 GADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECV 328 GAD +E++++G LH GE + + L++ GA +K + + A +G V Sbjct: 872 GADVNEKNNDGNTLLHLFSINGEVEVVQFLIQNGADFRLRNKERKSFFDLAVEFGHAGIV 931 Query: 327 DLLLKHGAAVTLQNMDGKT 271 ++ + GKT Sbjct: 932 GYAIEENKVDLQEPYRGKT 950
>HECD1_HUMAN (Q9ULT8) E3 ubiquitin-protein ligase HECTD1 (HECT domain-containing| protein 1) (E3 ligase for inhibin receptor) (EULIR) Length = 2612 Score = 67.4 bits (163), Expect = 4e-11 Identities = 40/109 (36%), Positives = 63/109 (57%), Gaps = 1/109 (0%) Frame = -1 Query: 540 DGEGLKKALDGGA-DKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPL 364 D + L A+D GA + + D G+ L++A +G + E L E GA V+ ++ + L Sbjct: 374 DTDALIDAIDTGAFEVNFMDDVGQTLLNWASAFGTQEMVEFLCERGADVNRGQRSSS--L 431 Query: 363 HYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLLE 217 HYAA +GR + LL+HGA L++ DGKTP+D A+ EV+ +L+ Sbjct: 432 HYAACFGRPQVAKTLLRHGANPDLRDEDGKTPLDKARERGHSEVVAILQ 480 Score = 37.7 bits (86), Expect = 0.031 Identities = 25/88 (28%), Positives = 44/88 (50%) Frame = -1 Query: 570 SIVHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDA 391 ++++ ++ G E ++ + GAD + + +LH+A +G + A+ LL GA D Sbjct: 398 TLLNWASAFGTQEMVEFLCERGADVNR--GQRSSSLHYAACFGRPQVAKTLLRHGANPDL 455 Query: 390 MDKNKNTPLHYAAGYGRKECVDLLLKHG 307 D++ TPL A G E V +L G Sbjct: 456 RDEDGKTPLDKARERGHSEVVAILQSPG 483
>NOTC4_MOUSE (P31695) Neurogenic locus notch homolog protein 4 precursor (Notch 4)| [Contains: Transforming protein Int-3; Notch 4 extracellular truncation; Notch 4 intracellular domain] Length = 1964 Score = 67.4 bits (163), Expect = 4e-11 Identities = 40/96 (41%), Positives = 52/96 (54%) Frame = -1 Query: 504 ADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVD 325 AD D G+ ALH+A + A LL+AGA DA D + TPL AA G E Sbjct: 1720 ADVGARDKRGKTALHWAAAVNNARAARSLLQAGADKDAQDSREQTPLFLAAREGAVEVAQ 1779 Query: 324 LLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLLE 217 LLL+ GAA L++ G P DVA+ + ++L LLE Sbjct: 1780 LLLELGAARGLRDQAGLAPGDVARQRSHWDLLTLLE 1815 Score = 44.3 bits (103), Expect = 3e-04 Identities = 38/112 (33%), Positives = 53/112 (47%), Gaps = 3/112 (2%) Frame = -1 Query: 546 VGDGEGLKKALDGGADKDEED-SEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNT 370 +G+ E + LD GA G LH A + A LLEAGA + D+ T Sbjct: 1605 LGNLEPWEPLLDRGACPQAHTVGTGETPLHLAARFSRPTAARRLLEAGANPNQPDRAGRT 1664 Query: 369 PLHYA-AGYGRKECVDLLLKHGAAVTLQNMDGKTPIDV-AKLNNQDEVLKLL 220 PLH A A R+ C LL +V + DG TP+ + A+L +D V +L+ Sbjct: 1665 PLHTAVAADAREVCQLLLASRQTSVDARTEDGTTPLMLAARLAVEDLVEELI 1716 Score = 43.5 bits (101), Expect = 6e-04 Identities = 30/92 (32%), Positives = 42/92 (45%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMD 385 +H A+V + + L GADKD +DS + L A G + A++LLE GAA D Sbjct: 1733 LHWAAAVNNARAARSLLQAGADKDAQDSREQTPLFLAAREGAVEVAQLLLELGAARGLRD 1792 Query: 384 KNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQ 289 + P A + + LL GA T Q Sbjct: 1793 QAGLAPGDVARQRSHWDLLTLL--EGAGPTTQ 1822 Score = 40.0 bits (92), Expect = 0.006 Identities = 34/115 (29%), Positives = 45/115 (39%), Gaps = 2/115 (1%) Frame = -1 Query: 558 HTASVGDGEGLKKALDGGADK--DEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMD 385 HTA D + + L D +G L A E L+ A A V A D Sbjct: 1667 HTAVAADAREVCQLLLASRQTSVDARTEDGTTPLMLAARLAVEDLVEELIAARADVGARD 1726 Query: 384 KNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 K T LH+AA LL+ GA Q+ +TP+ +A EV +LL Sbjct: 1727 KRGKTALHWAAAVNNARAARSLLQAGADKDAQDSREQTPLFLAAREGAVEVAQLL 1781
>UACA_MOUSE (Q8CGB3) Uveal autoantigen with coiled-coil domains and ankyrin| repeats protein (Nucling) (Nuclear membrane-binding protein) Length = 1411 Score = 67.4 bits (163), Expect = 4e-11 Identities = 41/117 (35%), Positives = 57/117 (48%) Frame = -1 Query: 570 SIVHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDA 391 S H AS G+ E L L G D DS GR ALH A YG C + LL+ + Sbjct: 72 SAFHVVASKGNLECLNAILTHGIDVATRDSAGRNALHLAAKYGHALCLQKLLQYNCPTEH 131 Query: 390 MDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 +D T LH A + LL HGA+V +++DG+TP+ +A + + +LL Sbjct: 132 VDLQGRTALHDAVMADCPSSIQLLCDHGASVNAKDIDGRTPLVLATQMCRPTICQLL 188 Score = 48.9 bits (115), Expect = 1e-05 Identities = 35/141 (24%), Positives = 54/141 (38%), Gaps = 1/141 (0%) Frame = -1 Query: 639 GTVSTAEPSXXXXXXXXXXXXXESIVHHTASVGDGEGLKKAL-DGGADKDEEDSEGRRAL 463 G S + P+ + + A GD E + L G + D EGR A Sbjct: 15 GPTSPSSPTAVASTQSAEWNKYDDRLMKAAERGDVEKVSSILAKKGVHPGKLDVEGRSAF 74 Query: 462 HFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNM 283 H G +C +L G V D LH AA YG C+ LL++ ++ Sbjct: 75 HVVASKGNLECLNAILTHGIDVATRDSAGRNALHLAAKYGHALCLQKLLQYNCPTEHVDL 134 Query: 282 DGKTPIDVAKLNNQDEVLKLL 220 G+T + A + + ++LL Sbjct: 135 QGRTALHDAVMADCPSSIQLL 155 Score = 36.2 bits (82), Expect = 0.091 Identities = 18/54 (33%), Positives = 28/54 (51%) Frame = -1 Query: 516 LDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYA 355 +D GAD + D + R AL C YG E+L++ GA + +D + +YA Sbjct: 189 IDRGADVNSRDKQNRTALMLGCEYGCRDAVEVLVKNGADLTLLDALGHDSSYYA 242
>NOTC4_HUMAN (Q99466) Neurogenic locus notch homolog protein 4 precursor (Notch 4)| (hNotch4) [Contains: Notch 4 extracellular truncation; Notch 4 intracellular domain] Length = 2003 Score = 67.4 bits (163), Expect = 4e-11 Identities = 41/96 (42%), Positives = 50/96 (52%) Frame = -1 Query: 504 ADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVD 325 AD D G+ ALH+A + A LL+AGA DA D + TPL AA G E Sbjct: 1725 ADVGARDKWGKTALHWAAAVNNARAARSLLQAGADKDAQDNREQTPLFLAAREGAVEVAQ 1784 Query: 324 LLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLLE 217 LLL GAA L++ G P DVA N ++L LLE Sbjct: 1785 LLLGLGAARELRDQAGLAPADVAHQRNHWDLLTLLE 1820 Score = 48.1 bits (113), Expect = 2e-05 Identities = 40/114 (35%), Positives = 54/114 (47%), Gaps = 3/114 (2%) Frame = -1 Query: 552 ASVGDGEGLKKALDGGADKDEED-SEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNK 376 A +G E + LDGGA G LH A + A LLEAGA + D+ Sbjct: 1608 AWLGCPEPWEPLLDGGACPQAHTVGTGETPLHLAARFSRPTAARRLLEAGANPNQPDRAG 1667 Query: 375 NTPLHYAAGYGRKECVDLLLK-HGAAVTLQNMDGKTPIDV-AKLNNQDEVLKLL 220 TPLH A +E LLL+ AV + DG TP+ + A+L +D V +L+ Sbjct: 1668 RTPLHAAVAADAREVCQLLLRSRQTAVDARTEDGTTPLMLAARLAVEDLVEELI 1721 Score = 43.9 bits (102), Expect = 4e-04 Identities = 34/118 (28%), Positives = 56/118 (47%), Gaps = 2/118 (1%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAG-AAVDAM 388 +H A ++ L+ GA+ ++ D GR LH A + ++LL + AVDA Sbjct: 1638 LHLAARFSRPTAARRLLEAGANPNQPDRAGRTPLHAAVAADAREVCQLLLRSRQTAVDAR 1697 Query: 387 DKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPID-VAKLNNQDEVLKLLE 217 ++ TPL AA ++ V+ L+ A V ++ GKT + A +NN LL+ Sbjct: 1698 TEDGTTPLMLAARLAVEDLVEELIAAQADVGARDKWGKTALHWAAAVNNARAARSLLQ 1755 Score = 40.0 bits (92), Expect = 0.006 Identities = 22/70 (31%), Positives = 34/70 (48%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMD 385 +H A+V + + L GADKD +D+ + L A G + A++LL GAA + D Sbjct: 1738 LHWAAAVNNARAARSLLQAGADKDAQDNREQTPLFLAAREGAVEVAQLLLGLGAARELRD 1797 Query: 384 KNKNTPLHYA 355 + P A Sbjct: 1798 QAGLAPADVA 1807 Score = 37.4 bits (85), Expect = 0.041 Identities = 29/92 (31%), Positives = 38/92 (41%) Frame = -1 Query: 495 DEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLL 316 D +G L A E L+ A A V A DK T LH+AA LL Sbjct: 1695 DARTEDGTTPLMLAARLAVEDLVEELIAAQADVGARDKWGKTALHWAAAVNNARAARSLL 1754 Query: 315 KHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 + GA Q+ +TP+ +A EV +LL Sbjct: 1755 QAGADKDAQDNREQTPLFLAAREGAVEVAQLL 1786
>ANK3_HUMAN (Q12955) Ankyrin-3 (ANK-3) (Ankyrin-G)| Length = 4377 Score = 67.4 bits (163), Expect = 4e-11 Identities = 39/118 (33%), Positives = 62/118 (52%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMD 385 +H A G + K LD A+ + + G LH AC K E+LL+ GA++ A+ Sbjct: 371 LHVAAHCGHYKVAKVLLDKKANPNAKALNGFTPLHIACKKNRIKVMELLLKHGASIQAVT 430 Query: 384 KNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLLEKD 211 ++ TP+H AA G V L+ HGA+ N+ G+T + +A + Q EV++ L +D Sbjct: 431 ESGLTPIHVAAFMGHVNIVSQLMHHGASPNTTNVRGETALHMAARSGQAEVVRYLVQD 488 Score = 66.2 bits (160), Expect = 8e-11 Identities = 38/115 (33%), Positives = 53/115 (46%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMD 385 +H A D + L + D E G LH A YG A +LL AAVD Sbjct: 206 LHIAARKDDTKAAALLLQNDNNADVESKSGFTPLHIAAHYGNINVATLLLNRAAAVDFTA 265 Query: 384 KNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 +N TPLH A+ G V LLL GA + + DG TP+ + ++V+++L Sbjct: 266 RNDITPLHVASKRGNANMVKLLLDRGAKIDAKTRDGLTPLHCGARSGHEQVVEML 320 Score = 65.1 bits (157), Expect = 2e-10 Identities = 40/115 (34%), Positives = 60/115 (52%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMD 385 +H + G E + + L A+ D +G ALH A G+ + ++L+ GA V+A Sbjct: 78 LHLASKEGHVEVVSELLQREANVDAATKKGNTALHIASLAGQAEVVKVLVTNGANVNAQS 137 Query: 384 KNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 +N TPL+ AA E V LL +GA+ +L DG TP+ VA D+V+ LL Sbjct: 138 QNGFTPLYMAAQENHLEVVKFLLDNGASQSLATEDGFTPLAVALQQGHDQVVSLL 192 Score = 63.5 bits (153), Expect = 5e-10 Identities = 42/106 (39%), Positives = 57/106 (53%), Gaps = 3/106 (2%) Frame = -1 Query: 528 LKKALD---GGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHY 358 L+KALD G D + + G ALH A G + LL+ A VDA K NT LH Sbjct: 54 LEKALDYIKNGVDINICNQNGLNALHLASKEGHVEVVSELLQREANVDAATKKGNTALHI 113 Query: 357 AAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 A+ G+ E V +L+ +GA V Q+ +G TP+ +A N EV+K L Sbjct: 114 ASLAGQAEVVKVLVTNGANVNAQSQNGFTPLYMAAQENHLEVVKFL 159 Score = 63.2 bits (152), Expect = 7e-10 Identities = 39/115 (33%), Positives = 57/115 (49%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMD 385 +H +A G + LD GA +G LH A YG+ + A +LL+ A+ DA Sbjct: 536 LHLSAREGHEDVAAFLLDHGASLSITTKKGFTPLHVAAKYGKLEVANLLLQKSASPDAAG 595 Query: 384 KNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 K+ TPLH AA Y ++ LLL GA+ +G TP+ +A NQ ++ L Sbjct: 596 KSGLTPLHVAAHYDNQKVALLLLDQGASPHAAAKNGYTPLHIAAKKNQMDIATTL 650 Score = 62.0 bits (149), Expect = 2e-09 Identities = 39/118 (33%), Positives = 60/118 (50%), Gaps = 1/118 (0%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMD 385 +H +A +G + +++ L GA + + G LH + G A LL+ GA++ Sbjct: 503 LHISARLGKADIVQQLLQQGASPNAATTSGYTPLHLSAREGHEDVAAFLLDHGASLSITT 562 Query: 384 KNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDV-AKLNNQDEVLKLLEK 214 K TPLH AA YG+ E +LLL+ A+ G TP+ V A +NQ L LL++ Sbjct: 563 KKGFTPLHVAAKYGKLEVANLLLQKSASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQ 620 Score = 60.5 bits (145), Expect = 4e-09 Identities = 36/115 (31%), Positives = 52/115 (45%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMD 385 VH A G + + L A+ + + G LH A AE+L+ GA VDA Sbjct: 668 VHLAAQEGHVDMVSLLLGRNANVNLSNKSGLTPLHLAAQEDRVNVAEVLVNQGAHVDAQT 727 Query: 384 KNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 K TPLH YG + V+ LL+H A V + +G TP+ A ++ +L Sbjct: 728 KMGYTPLHVGCHYGNIKIVNFLLQHSAKVNAKTKNGYTPLHQAAQQGHTHIINVL 782 Score = 60.1 bits (144), Expect = 6e-09 Identities = 33/115 (28%), Positives = 56/115 (48%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMD 385 +H A +G + + + GA + + G ALH A G+ + L++ GA V+A Sbjct: 437 IHVAAFMGHVNIVSQLMHHGASPNTTNVRGETALHMAARSGQAEVVRYLVQDGAQVEAKA 496 Query: 384 KNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 K+ TPLH +A G+ + V LL+ GA+ G TP+ ++ ++V L Sbjct: 497 KDDQTPLHISARLGKADIVQQLLQQGASPNAATTSGYTPLHLSAREGHEDVAAFL 551 Score = 59.3 bits (142), Expect = 1e-08 Identities = 34/103 (33%), Positives = 52/103 (50%), Gaps = 1/103 (0%) Frame = -1 Query: 558 HTASVGDGEGLKKAL-DGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDK 382 H A+ D + + L + GA D + G LH C YG K LL+ A V+A K Sbjct: 702 HLAAQEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGNIKIVNFLLQHSAKVNAKTK 761 Query: 381 NKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAK 253 N TPLH AA G +++LL++ A+ ++G T + +A+ Sbjct: 762 NGYTPLHQAAQQGHTHIINVLLQNNASPNELTVNGNTALGIAR 804 Score = 59.3 bits (142), Expect = 1e-08 Identities = 34/115 (29%), Positives = 58/115 (50%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMD 385 +H A G E ++ + GA + + + + LH + G+ + LL+ GA+ +A Sbjct: 470 LHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTPLHISARLGKADIVQQLLQQGASPNAAT 529 Query: 384 KNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 + TPLH +A G ++ LL HGA++++ G TP+ VA + EV LL Sbjct: 530 TSGYTPLHLSAREGHEDVAAFLLDHGASLSITTKKGFTPLHVAAKYGKLEVANLL 584 Score = 57.4 bits (137), Expect = 4e-08 Identities = 37/102 (36%), Positives = 53/102 (51%), Gaps = 1/102 (0%) Frame = -1 Query: 558 HTASVGDGEG-LKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDK 382 H A+ GD ++ L D+ ++ ALH A G +K A++LL+ A +A Sbjct: 339 HMATQGDHLNCVQLLLQHNVPVDDVTNDYLTALHVAAHCGHYKVAKVLLDKKANPNAKAL 398 Query: 381 NKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVA 256 N TPLH A R + ++LLLKHGA++ G TPI VA Sbjct: 399 NGFTPLHIACKKNRIKVMELLLKHGASIQAVTESGLTPIHVA 440 Score = 52.8 bits (125), Expect = 9e-07 Identities = 36/115 (31%), Positives = 52/115 (45%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMD 385 +H + G+ +K LD GA D + +G LH G + E+LL+ A + + Sbjct: 272 LHVASKRGNANMVKLLLDRGAKIDAKTRDGLTPLHCGARSGHEQVVEMLLDRAAPILSKT 331 Query: 384 KNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 KN +PLH A CV LLL+H V D T + VA +V K+L Sbjct: 332 KNGLSPLHMATQGDHLNCVQLLLQHNVPVDDVTNDYLTALHVAAHCGHYKVAKVL 386 Score = 52.0 bits (123), Expect = 2e-06 Identities = 34/94 (36%), Positives = 45/94 (47%), Gaps = 3/94 (3%) Frame = -1 Query: 492 EEDSEGR---RALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDL 322 E D++G+ ALH A + K A +LL+ D K+ TPLH AA YG L Sbjct: 194 ENDTKGKVRLPALHIAARKDDTKAAALLLQNDNNADVESKSGFTPLHIAAHYGNINVATL 253 Query: 321 LLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 LL AAV + TP+ VA ++KLL Sbjct: 254 LLNRAAAVDFTARNDITPLHVASKRGNANMVKLL 287 Score = 51.6 bits (122), Expect = 2e-06 Identities = 35/115 (30%), Positives = 48/115 (41%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMD 385 +H A G E L A D G LH A Y K A +LL+ GA+ A Sbjct: 569 LHVAAKYGKLEVANLLLQKSASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQGASPHAAA 628 Query: 384 KNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 KN TPLH AA + + LL++GA G + +A +++ LL Sbjct: 629 KNGYTPLHIAAKKNQMDIATTLLEYGADANAVTRQGIASVHLAAQEGHVDMVSLL 683 Score = 51.2 bits (121), Expect = 3e-06 Identities = 33/99 (33%), Positives = 45/99 (45%) Frame = -1 Query: 516 LDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRK 337 LD GA G LH A + A LLE GA +A+ + +H AA G Sbjct: 618 LDQGASPHAAAKNGYTPLHIAAKKNQMDIATTLLEYGADANAVTRQGIASVHLAAQEGHV 677 Query: 336 ECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 + V LLL A V L N G TP+ +A ++ V ++L Sbjct: 678 DMVSLLLGRNANVNLSNKSGLTPLHLAAQEDRVNVAEVL 716 Score = 48.1 bits (113), Expect = 2e-05 Identities = 29/86 (33%), Positives = 42/86 (48%) Frame = -1 Query: 516 LDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRK 337 L+ GAD + +G ++H A G +LL A V+ +K+ TPLH AA R Sbjct: 651 LEYGADANAVTRQGIASVHLAAQEGHVDMVSLLLGRNANVNLSNKSGLTPLHLAAQEDRV 710 Query: 336 ECVDLLLKHGAAVTLQNMDGKTPIDV 259 ++L+ GA V Q G TP+ V Sbjct: 711 NVAEVLVNQGAHVDAQTKMGYTPLHV 736 Score = 36.6 bits (83), Expect = 0.070 Identities = 22/85 (25%), Positives = 39/85 (45%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMD 385 +H + G E +K + GA+ + + G L+ A + + LL+ GA+ Sbjct: 111 LHIASLAGQAEVVKVLVTNGANVNAQSQNGFTPLYMAAQENHLEVVKFLLDNGASQSLAT 170 Query: 384 KNKNTPLHYAAGYGRKECVDLLLKH 310 ++ TPL A G + V LLL++ Sbjct: 171 EDGFTPLAVALQQGHDQVVSLLLEN 195
>UACA_BOVIN (Q8HYY4) Uveal autoantigen with coiled-coil domains and ankyrin| repeats protein (Beta-actin-binding protein) (BetaCAP73) Length = 1401 Score = 67.4 bits (163), Expect = 4e-11 Identities = 41/117 (35%), Positives = 58/117 (49%) Frame = -1 Query: 570 SIVHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDA 391 S H AS G+ E L L G D D+ GR ALH A YG C + LL+ + Sbjct: 57 SAFHVVASKGNLECLNAILIHGVDITTSDTAGRNALHLAAKYGHALCLQKLLQYNCPTEH 116 Query: 390 MDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 +D T LH AA + LL HGA+V +++DG+TP+ +A + + +LL Sbjct: 117 VDLQGRTALHDAAMADCPSSIQLLCDHGASVNAKDVDGRTPLVLATQMCRPTICQLL 173 Score = 55.1 bits (131), Expect = 2e-07 Identities = 34/115 (29%), Positives = 60/115 (52%), Gaps = 1/115 (0%) Frame = -1 Query: 558 HTASVGD-GEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDK 382 H A++ D ++ D GA + +D +GR L A ++L++ GA +++ DK Sbjct: 126 HDAAMADCPSSIQLLCDHGASVNAKDVDGRTPLVLATQMCRPTICQLLIDRGADINSRDK 185 Query: 381 NKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLLE 217 T L YG K+ V++L+K+GA VTL + G A++ + ++L LL+ Sbjct: 186 QNRTALMLGCEYGCKDAVEVLIKNGADVTLLDALGHDSSYYARIGDNLDILTLLK 240 Score = 48.1 bits (113), Expect = 2e-05 Identities = 31/112 (27%), Positives = 48/112 (42%), Gaps = 1/112 (0%) Frame = -1 Query: 552 ASVGDGEGLKKAL-DGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNK 376 A GD E + L G + + D EGR A H G +C +L G + D Sbjct: 29 AERGDVEKVSSILAKKGVNPGKLDVEGRSAFHVVASKGNLECLNAILIHGVDITTSDTAG 88 Query: 375 NTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 LH AA YG C+ LL++ ++ G+T + A + + ++LL Sbjct: 89 RNALHLAAKYGHALCLQKLLQYNCPTEHVDLQGRTALHDAAMADCPSSIQLL 140
>ANKK1_MOUSE (Q8BZ25) Ankyrin repeat and protein kinase domain-containing| protein 1 (EC 2.7.11.1) Length = 745 Score = 67.0 bits (162), Expect = 5e-11 Identities = 44/131 (33%), Positives = 69/131 (52%), Gaps = 1/131 (0%) Frame = -1 Query: 558 HTASVGDGEGLKKALDG-GADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDK 382 H A+ GL K L G GA+ D + R LH A G+ + + LL+ GA DA+D Sbjct: 507 HVAAYFGHIGLVKLLSGQGAELDAQQRNLRTPLHLAVERGKVRAIQHLLKCGALPDALDH 566 Query: 381 NKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLLEKDVFL 202 + +PLH AA G+ +LL++GA++ L+ G TP+ +A E++ L K + Sbjct: 567 SGYSPLHIAAARGKDLIFKMLLRYGASLELRTQQGWTPLHLATYKGHLEIIHQLAKS-HV 625 Query: 201 *IASLGSHEET 169 + +LGS + T Sbjct: 626 DLDALGSMQWT 636 Score = 60.8 bits (146), Expect = 3e-09 Identities = 35/114 (30%), Positives = 56/114 (49%), Gaps = 1/114 (0%) Frame = -1 Query: 558 HTASVGDGEGLKKAL-DGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDK 382 H A+ + E + + L AD ++EG+ LH A +G ++L GA +DA + Sbjct: 474 HLAAQNNFENVARLLVSRQADLSPHEAEGKTPLHVAAYFGHIGLVKLLSGQGAELDAQQR 533 Query: 381 NKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 N TPLH A G+ + LLK GA + G +P+ +A +D + K+L Sbjct: 534 NLRTPLHLAVERGKVRAIQHLLKCGALPDALDHSGYSPLHIAAARGKDLIFKML 587 Score = 57.0 bits (136), Expect = 5e-08 Identities = 35/96 (36%), Positives = 50/96 (52%) Frame = -1 Query: 507 GADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECV 328 GAD + D +G LHFA G+ A +LL+ GA V+A + TPLH AA + Sbjct: 426 GADTNLADEDGWAPLHFAAQNGDDHTARLLLDHGALVNAREHEGWTPLHLAAQNNFENVA 485 Query: 327 DLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 LL+ A ++ +GKTP+ VA ++KLL Sbjct: 486 RLLVSRQADLSPHEAEGKTPLHVAAYFGHIGLVKLL 521 Score = 54.3 bits (129), Expect = 3e-07 Identities = 36/115 (31%), Positives = 54/115 (46%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMD 385 +H + G E ++ L D D + + G L A + +LL GA + D Sbjct: 374 LHFLVAGGSLEQVRLLLSHDVDVDCQTASGYTPLLIATQDQQPDLCALLLAHGADTNLAD 433 Query: 384 KNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 ++ PLH+AA G LLL HGA V + +G TP+ +A NN + V +LL Sbjct: 434 EDGWAPLHFAAQNGDDHTARLLLDHGALVNAREHEGWTPLHLAAQNNFENVARLL 488 Score = 48.5 bits (114), Expect = 2e-05 Identities = 32/103 (31%), Positives = 46/103 (44%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMD 385 +H A GD + LD GA + + EG LH A A +L+ A + + Sbjct: 440 LHFAAQNGDDHTARLLLDHGALVNAREHEGWTPLHLAAQNNFENVARLLVSRQADLSPHE 499 Query: 384 KNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVA 256 TPLH AA +G V LL GA + Q + +TP+ +A Sbjct: 500 AEGKTPLHVAAYFGHIGLVKLLSGQGAELDAQQRNLRTPLHLA 542 Score = 45.4 bits (106), Expect = 1e-04 Identities = 36/117 (30%), Positives = 51/117 (43%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMD 385 +H G E + + D D S LH A GE LL+ GA +A + Sbjct: 605 LHLATYKGHLEIIHQLAKSHVDLDALGSMQWTPLHLAAFQGEEGVMLALLQCGANPNAAE 664 Query: 384 KNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLLEK 214 ++ TPLH A G + LL++GA + N G TP +A L +LK+L K Sbjct: 665 QSGWTPLHLAVHKGTFLGITHLLEYGADIHACNKVGWTPAHLAALKGNTAILKVLVK 721 Score = 44.3 bits (103), Expect = 3e-04 Identities = 34/102 (33%), Positives = 48/102 (47%), Gaps = 1/102 (0%) Frame = -1 Query: 558 HTASVGDGEGLKKAL-DGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDK 382 H A+ EG+ AL GA+ + + G LH A G F LLE GA + A +K Sbjct: 639 HLAAFQGEEGVMLALLQCGANPNAAEQSGWTPLHLAVHKGTFLGITHLLEYGADIHACNK 698 Query: 381 NKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVA 256 TP H AA G + +L+K A V ++ TP+ +A Sbjct: 699 VGWTPAHLAALKGNTAILKVLVKAAAQVDVKGGVSCTPLQLA 740 Score = 41.2 bits (95), Expect = 0.003 Identities = 31/105 (29%), Positives = 46/105 (43%) Frame = -1 Query: 570 SIVHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDA 391 S +H A+ G K L GA + +G LH A G + L ++ +DA Sbjct: 570 SPLHIAAARGKDLIFKMLLRYGASLELRTQQGWTPLHLATYKGHLEIIHQLAKSHVDLDA 629 Query: 390 MDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVA 256 + + TPLH AA G + + LL+ GA G TP+ +A Sbjct: 630 LGSMQWTPLHLAAFQGEEGVMLALLQCGANPNAAEQSGWTPLHLA 674 Score = 40.8 bits (94), Expect = 0.004 Identities = 30/115 (26%), Positives = 47/115 (40%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMD 385 +H G ++ L GA D D G LH A G+ ++LL GA+++ Sbjct: 539 LHLAVERGKVRAIQHLLKCGALPDALDHSGYSPLHIAAARGKDLIFKMLLRYGASLELRT 598 Query: 384 KNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 + TPLH A G E + L K + TP+ +A ++ V+ L Sbjct: 599 QQGWTPLHLATYKGHLEIIHQLAKSHVDLDALGSMQWTPLHLAAFQGEEGVMLAL 653 Score = 39.7 bits (91), Expect = 0.008 Identities = 21/55 (38%), Positives = 29/55 (52%) Frame = -1 Query: 384 KNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 +N+ TPLH+ G E V LLL H V Q G TP+ +A + Q ++ LL Sbjct: 368 ENRVTPLHFLVAGGSLEQVRLLLSHDVDVDCQTASGYTPLLIATQDQQPDLCALL 422
>PSD10_MOUSE (Q9Z2X2) 26S proteasome non-ATPase regulatory subunit 10 (26S| proteasome regulatory subunit p28) (Gankyrin) Length = 231 Score = 66.6 bits (161), Expect = 6e-11 Identities = 38/104 (36%), Positives = 53/104 (50%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMD 385 +H+ AS E L+GGA+ D +D A+H A G K ILL A+ + D Sbjct: 110 LHYAASKNRHEIAVMLLEGGANPDAKDHYDATAMHRAAAKGNLKMVHILLFYKASTNIQD 169 Query: 384 KNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAK 253 NTPLH A R E L+ GA++ ++N + KTP+ VAK Sbjct: 170 TEGNTPLHLACDEERVEEAKFLVTQGASIYIENKEEKTPLQVAK 213 Score = 65.1 bits (157), Expect = 2e-10 Identities = 36/89 (40%), Positives = 47/89 (52%) Frame = -1 Query: 486 DSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLLKHG 307 D + R ALH+AC G + E LL+ G V+ D +PLH AA GR E V LL G Sbjct: 37 DQDSRTALHWACSAGHTEIVEFLLQLGVPVNDKDDAGWSPLHIAASAGRDEIVKALLVKG 96 Query: 306 AAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 A V N +G TP+ A N+ E+ +L Sbjct: 97 AHVNAVNQNGCTPLHYAASKNRHEIAVML 125 Score = 61.6 bits (148), Expect = 2e-09 Identities = 40/117 (34%), Positives = 58/117 (49%) Frame = -1 Query: 570 SIVHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDA 391 S +H AS G E +K L GA + + G LH+A + A +LLE GA DA Sbjct: 75 SPLHIAASAGRDEIVKALLVKGAHVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPDA 134 Query: 390 MDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 D T +H AA G + V +LL + A+ +Q+ +G TP+ +A + E K L Sbjct: 135 KDHYDATAMHRAAAKGNLKMVHILLFYKASTNIQDTEGNTPLHLACDEERVEEAKFL 191 Score = 55.8 bits (133), Expect = 1e-07 Identities = 36/106 (33%), Positives = 52/106 (49%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMD 385 +H S G E ++ L G +++D G LH A G + + LL GA V+A++ Sbjct: 44 LHWACSAGHTEIVEFLLQLGVPVNDKDDAGWSPLHIAASAGRDEIVKALLVKGAHVNAVN 103 Query: 384 KNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLN 247 +N TPLHYAA R E +LL+ GA N D K D ++ Sbjct: 104 QNGCTPLHYAASKNRHEIAVMLLEGGA-----NPDAKDHYDATAMH 144 Score = 38.1 bits (87), Expect = 0.024 Identities = 22/72 (30%), Positives = 37/72 (51%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMD 385 +H A+ G+ + + L A + +D+EG LH AC + A+ L+ GA++ + Sbjct: 143 MHRAAAKGNLKMVHILLFYKASTNIQDTEGNTPLHLACDEERVEEAKFLVTQGASIYIEN 202 Query: 384 KNKNTPLHYAAG 349 K + TPL A G Sbjct: 203 KEEKTPLQVAKG 214
>ANKR5_MOUSE (Q9D2J7) Ankyrin repeat domain-containing protein 5| Length = 775 Score = 66.6 bits (161), Expect = 6e-11 Identities = 35/96 (36%), Positives = 55/96 (57%) Frame = -1 Query: 543 GDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPL 364 GD LKKA++ G D +D+ + L AC G + L+E GA V+A D TPL Sbjct: 503 GDLASLKKAIETGIPVDMKDNTYKTPLMIACASGNIDVVKFLIEKGANVNATDNFLWTPL 562 Query: 363 HYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVA 256 H+A G+++ V+LL+K GA++ +++ TP+ A Sbjct: 563 HFACHAGQQDIVELLVKAGASIDATSINNSTPLSRA 598 Score = 59.7 bits (143), Expect = 8e-09 Identities = 34/110 (30%), Positives = 60/110 (54%) Frame = -1 Query: 543 GDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPL 364 G+ + +K ++ GA+ + D+ LHFAC G+ E+L++AGA++DA N +TPL Sbjct: 536 GNIDVVKFLIEKGANVNATDNFLWTPLHFACHAGQQDIVELLVKAGASIDATSINNSTPL 595 Query: 363 HYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLLEK 214 A R + V LL GA ++N G +D+AK ++ ++++ Sbjct: 596 SRAIESCRLDTVKYLLDMGAKFQIENRKGHAAMDIAKAYADYRIIDMIKE 645 Score = 50.4 bits (119), Expect = 5e-06 Identities = 28/94 (29%), Positives = 48/94 (51%) Frame = -1 Query: 534 EGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYA 355 E ++ L+ G + + D++ A HFA G F ++L + + + NTPLH+A Sbjct: 199 EIVRGILERGGEVNAYDNDRHHAAHFAAKGGFFDILKLLFAYNGDMGLIGMDGNTPLHFA 258 Query: 354 AGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAK 253 A G +C + + G + +N++ KTP VAK Sbjct: 259 AMGGFADCCKYIAQRGCDLKWKNLEHKTPRVVAK 292 Score = 42.7 bits (99), Expect = 0.001 Identities = 29/100 (29%), Positives = 48/100 (48%), Gaps = 1/100 (1%) Frame = -1 Query: 516 LDGGADKDE-EDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGR 340 L+ GA+ + S GR AL + G + +LE G V+A D +++ H+AA G Sbjct: 171 LEKGANPNAINTSTGRTALMESSREGVLEIVRGILERGGEVNAYDNDRHHAAHFAAKGGF 230 Query: 339 KECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 + + LL + + L MDG TP+ A + + K + Sbjct: 231 FDILKLLFAYNGDMGLIGMDGNTPLHFAAMGGFADCCKYI 270 Score = 37.0 bits (84), Expect = 0.053 Identities = 24/84 (28%), Positives = 37/84 (44%) Frame = -1 Query: 465 LHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQN 286 + F G+ + +E G VD D TPL A G + V L++ GA V + Sbjct: 496 ISFITKAGDLASLKKAIETGIPVDMKDNTYKTPLMIACASGNIDVVKFLIEKGANVNATD 555 Query: 285 MDGKTPIDVAKLNNQDEVLKLLEK 214 TP+ A Q ++++LL K Sbjct: 556 NFLWTPLHFACHAGQQDIVELLVK 579
>UACA_CANFA (Q9GL21) Uveal autoantigen with coiled-coil domains and ankyrin| repeats protein Length = 1415 Score = 66.6 bits (161), Expect = 6e-11 Identities = 41/117 (35%), Positives = 57/117 (48%) Frame = -1 Query: 570 SIVHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDA 391 S H AS G+ E L L G D D+ GR ALH A YG C + LL+ + Sbjct: 72 SAFHVVASKGNLECLNAILIHGVDITTSDTAGRNALHLAAKYGHALCLQKLLQYNCPTEH 131 Query: 390 MDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 D T LH AA + LL HGA+V +++DG+TP+ +A + + +LL Sbjct: 132 ADLQGRTALHDAAMADCPSSIQLLCDHGASVNAKDVDGRTPLVLATQMCRPAICQLL 188 Score = 48.1 bits (113), Expect = 2e-05 Identities = 31/112 (27%), Positives = 48/112 (42%), Gaps = 1/112 (0%) Frame = -1 Query: 552 ASVGDGEGLKKAL-DGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNK 376 A GD E + L G + + D EGR A H G +C +L G + D Sbjct: 44 AERGDVEKVSSILAKKGINPGKLDVEGRSAFHVVASKGNLECLNAILIHGVDITTSDTAG 103 Query: 375 NTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 LH AA YG C+ LL++ ++ G+T + A + + ++LL Sbjct: 104 RNALHLAAKYGHALCLQKLLQYNCPTEHADLQGRTALHDAAMADCPSSIQLL 155 Score = 37.0 bits (84), Expect = 0.053 Identities = 19/54 (35%), Positives = 28/54 (51%) Frame = -1 Query: 516 LDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYA 355 +D GA+ + D + R AL C YG E+LL+ GA V +D + +YA Sbjct: 189 IDRGAEINSRDKQNRTALMLGCEYGCKDAVEVLLKNGADVSLLDALGHDSSYYA 242
>ANK2_HUMAN (Q01484) Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin,| nonerythroid) Length = 3924 Score = 66.2 bits (160), Expect = 8e-11 Identities = 39/115 (33%), Positives = 56/115 (48%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMD 385 +H A +G + L GA D + G ALH A G+ + LL GA VDA Sbjct: 435 IHVAAFMGHLNIVLLLLQNGASPDVTNIRGETALHMAARAGQVEVVRCLLRNGALVDARA 494 Query: 384 KNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 + + TPLH A+ G+ E V LLL+H A +G TP+ ++ Q +V +L Sbjct: 495 REEQTPLHIASRLGKTEIVQLLLQHMAHPDAATTNGYTPLHISAREGQVDVASVL 549 Score = 65.5 bits (158), Expect = 1e-10 Identities = 35/85 (41%), Positives = 45/85 (52%) Frame = -1 Query: 507 GADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECV 328 GAD+D G L AC YG K LL+ GA V+A KN TPLH AA G + Sbjct: 718 GADQDAHTKLGYTPLIVACHYGNVKMVNFLLKQGANVNAKTKNGYTPLHQAAQQGHTHII 777 Query: 327 DLLLKHGAAVTLQNMDGKTPIDVAK 253 ++LL+HGA +G T + +AK Sbjct: 778 NVLLQHGAKPNATTANGNTALAIAK 802 Score = 65.1 bits (157), Expect = 2e-10 Identities = 44/118 (37%), Positives = 58/118 (49%), Gaps = 1/118 (0%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMD 385 +H + +G E ++ L A D + G LH + G+ A +LLEAGAA Sbjct: 501 LHIASRLGKTEIVQLLLQHMAHPDAATTNGYTPLHISAREGQVDVASVLLEAGAAHSLAT 560 Query: 384 KNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDV-AKLNNQDEVLKLLEK 214 K TPLH AA YG + LLL+ AA +G TP+ V A +NQ L LLEK Sbjct: 561 KKGFTPLHVAAKYGSLDVAKLLLQRRAAADSAGKNGLTPLHVAAHYDNQKVALLLLEK 618 Score = 64.7 bits (156), Expect = 2e-10 Identities = 39/115 (33%), Positives = 57/115 (49%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMD 385 +H +A G + L+ GA +G LH A YG A++LL+ AA D+ Sbjct: 534 LHISAREGQVDVASVLLEAGAAHSLATKKGFTPLHVAAKYGSLDVAKLLLQRRAAADSAG 593 Query: 384 KNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 KN TPLH AA Y ++ LLL+ GA+ +G TP+ +A NQ ++ L Sbjct: 594 KNGLTPLHVAAHYDNQKVALLLLEKGASPHATAKNGYTPLHIAAKKNQMQIASTL 648 Score = 63.9 bits (154), Expect = 4e-10 Identities = 35/86 (40%), Positives = 45/86 (52%) Frame = -1 Query: 477 GRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLLKHGAAV 298 G LH A YG A +LL GAAVD +N TPLH A+ G V LLL G + Sbjct: 233 GFTPLHIAAHYGNVNVATLLLNRGAAVDFTARNGITPLHVASKRGNTNMVKLLLDRGGQI 292 Query: 297 TLQNMDGKTPIDVAKLNNQDEVLKLL 220 + DG TP+ A + D+V++LL Sbjct: 293 DAKTRDGLTPLHCAARSGHDQVVELL 318 Score = 62.0 bits (149), Expect = 2e-09 Identities = 38/115 (33%), Positives = 60/115 (52%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMD 385 +H A G K LD A+ + G LH AC K E+L++ GA++ A+ Sbjct: 369 LHVAAHCGHYRVTKLLLDKRANPNARALNGFTPLHIACKKNRIKVMELLVKYGASIQAIT 428 Query: 384 KNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 ++ TP+H AA G V LLL++GA+ + N+ G+T + +A Q EV++ L Sbjct: 429 ESGLTPIHVAAFMGHLNIVLLLLQNGASPDVTNIRGETALHMAARAGQVEVVRCL 483 Score = 60.1 bits (144), Expect = 6e-09 Identities = 38/115 (33%), Positives = 51/115 (44%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMD 385 +H A G + K L A D G LH A Y K A +LLE GA+ A Sbjct: 567 LHVAAKYGSLDVAKLLLQRRAAADSAGKNGLTPLHVAAHYDNQKVALLLLEKGASPHATA 626 Query: 384 KNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 KN TPLH AA + + LL +GA + G TP+ +A +++ LL Sbjct: 627 KNGYTPLHIAAKKNQMQIASTLLNYGAETNIVTKQGVTPLHLASQEGHTDMVTLL 681 Score = 60.1 bits (144), Expect = 6e-09 Identities = 42/115 (36%), Positives = 55/115 (47%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMD 385 +H + G+ +K LD G D + +G LH A G + E+LLE GA + A Sbjct: 270 LHVASKRGNTNMVKLLLDRGGQIDAKTRDGLTPLHCAARSGHDQVVELLLERGAPLLART 329 Query: 384 KNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 KN +PLH AA ECV LL+H A V +D T + VA V KLL Sbjct: 330 KNGLSPLHMAAQGDHVECVKHLLQHKAPVDDVTLDYLTALHVAAHCGHYRVTKLL 384 Score = 59.7 bits (143), Expect = 8e-09 Identities = 40/115 (34%), Positives = 57/115 (49%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMD 385 +H A G E ++ L GA D E + LH A G+ + ++LL+ A DA Sbjct: 468 LHMAARAGQVEVVRCLLRNGALVDARAREEQTPLHIASRLGKTEIVQLLLQHMAHPDAAT 527 Query: 384 KNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 N TPLH +A G+ + +LL+ GAA +L G TP+ VA +V KLL Sbjct: 528 TNGYTPLHISAREGQVDVASVLLEAGAAHSLATKKGFTPLHVAAKYGSLDVAKLL 582 Score = 57.4 bits (137), Expect = 4e-08 Identities = 38/119 (31%), Positives = 61/119 (51%), Gaps = 1/119 (0%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMD 385 +H A G +++ L G+ D +G ALH A G+ + ++L++ GA ++A Sbjct: 68 LHLAAKEGHVGLVQELLGRGSSVDSATKKGNTALHIASLAGQAEVVKVLVKEGANINAQS 127 Query: 384 KNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVA-KLNNQDEVLKLLEKD 211 +N TPL+ AA + V LL++GA + DG TP+ VA + + V LLE D Sbjct: 128 QNGFTPLYMAAQENHIDVVKYLLENGANQSTATEDGFTPLAVALQQGHNQAVAILLEND 186 Score = 57.0 bits (136), Expect = 5e-08 Identities = 36/115 (31%), Positives = 56/115 (48%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMD 385 +H A G+ L+ GA D G LH A G ++LL+ G +DA Sbjct: 237 LHIAAHYGNVNVATLLLNRGAAVDFTARNGITPLHVASKRGNTNMVKLLLDRGGQIDAKT 296 Query: 384 KNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 ++ TPLH AA G + V+LLL+ GA + + +G +P+ +A + E +K L Sbjct: 297 RDGLTPLHCAARSGHDQVVELLLERGAPLLARTKNGLSPLHMAAQGDHVECVKHL 351 Score = 55.8 bits (133), Expect = 1e-07 Identities = 36/115 (31%), Positives = 53/115 (46%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMD 385 +H + G + + LD GA+ G +LH A + A+IL + GA DA Sbjct: 666 LHLASQEGHTDMVTLLLDKGANIHMSTKSGLTSLHLAAQEDKVNVADILTKHGADQDAHT 725 Query: 384 KNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 K TPL A YG + V+ LLK GA V + +G TP+ A ++ +L Sbjct: 726 KLGYTPLIVACHYGNVKMVNFLLKQGANVNAKTKNGYTPLHQAAQQGHTHIINVL 780 Score = 55.1 bits (131), Expect = 2e-07 Identities = 38/114 (33%), Positives = 57/114 (50%), Gaps = 1/114 (0%) Frame = -1 Query: 558 HTASVGDG-EGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDK 382 H A+ GD E +K L A D+ + ALH A G ++ ++LL+ A +A Sbjct: 337 HMAAQGDHVECVKHLLQHKAPVDDVTLDYLTALHVAAHCGHYRVTKLLLDKRANPNARAL 396 Query: 381 NKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 N TPLH A R + ++LL+K+GA++ G TPI VA ++ LL Sbjct: 397 NGFTPLHIACKKNRIKVMELLVKYGASIQAITESGLTPIHVAAFMGHLNIVLLL 450 Score = 49.7 bits (117), Expect = 8e-06 Identities = 31/101 (30%), Positives = 45/101 (44%) Frame = -1 Query: 516 LDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRK 337 L+ GA G LH A + + A LL GA + + K TPLH A+ G Sbjct: 616 LEKGASPHATAKNGYTPLHIAAKKNQMQIASTLLNYGAETNIVTKQGVTPLHLASQEGHT 675 Query: 336 ECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLLEK 214 + V LLL GA + + G T + +A ++ V +L K Sbjct: 676 DMVTLLLDKGANIHMSTKSGLTSLHLAAQEDKVNVADILTK 716 Score = 48.9 bits (115), Expect = 1e-05 Identities = 35/117 (29%), Positives = 54/117 (46%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMD 385 +H A G + ++ L+ GA G LH A +C + LL+ A VD + Sbjct: 303 LHCAARSGHDQVVELLLERGAPLLARTKNGLSPLHMAAQGDHVECVKHLLQHKAPVDDVT 362 Query: 384 KNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLLEK 214 + T LH AA G LLL A + ++G TP+ +A N+ +V++LL K Sbjct: 363 LDYLTALHVAAHCGHYRVTKLLLDKRANPNARALNGFTPLHIACKKNRIKVMELLVK 419 Score = 45.1 bits (105), Expect = 2e-04 Identities = 29/87 (33%), Positives = 40/87 (45%) Frame = -1 Query: 516 LDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRK 337 L+ GA+ + +G LH A G +LL+ GA + K+ T LH AA + Sbjct: 649 LNYGAETNIVTKQGVTPLHLASQEGHTDMVTLLLDKGANIHMSTKSGLTSLHLAAQEDKV 708 Query: 336 ECVDLLLKHGAAVTLQNMDGKTPIDVA 256 D+L KHGA G TP+ VA Sbjct: 709 NVADILTKHGADQDAHTKLGYTPLIVA 735
>PSD10_RAT (Q9Z2X3) 26S proteasome non-ATPase regulatory subunit 10 (26S| proteasome regulatory subunit p28) (Gankyrin) Length = 231 Score = 66.2 bits (160), Expect = 8e-11 Identities = 38/104 (36%), Positives = 54/104 (51%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMD 385 +H+ AS E L+GGA+ D ++ A+H A G K ILL A+ + D Sbjct: 110 LHYAASKNRHEIAVMLLEGGANPDAKNHYDATAMHRAAAKGNLKMVHILLFYKASTNIQD 169 Query: 384 KNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAK 253 NTPLH A R E LL+ GA++ ++N + KTP+ VAK Sbjct: 170 TEGNTPLHLACDEERVEEAKLLVTQGASIYIENKEEKTPLQVAK 213 Score = 63.5 bits (153), Expect = 5e-10 Identities = 41/117 (35%), Positives = 60/117 (51%) Frame = -1 Query: 570 SIVHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDA 391 S +H AS G E +K L GA + + G ALH+A + A +LLE GA DA Sbjct: 75 SPLHIAASAGRDEIVKALLIKGAQVNAVNQNGCTALHYAASKNRHEIAVMLLEGGANPDA 134 Query: 390 MDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 + T +H AA G + V +LL + A+ +Q+ +G TP+ +A + E KLL Sbjct: 135 KNHYDATAMHRAAAKGNLKMVHILLFYKASTNIQDTEGNTPLHLACDEERVEEAKLL 191 Score = 62.4 bits (150), Expect = 1e-09 Identities = 35/89 (39%), Positives = 46/89 (51%) Frame = -1 Query: 486 DSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLLKHG 307 D + R ALH+AC G + E LL+ G V+ D +PLH AA GR E V LL G Sbjct: 37 DQDSRTALHWACSAGHTEIVEFLLQLGVPVNEKDDAGWSPLHIAASAGRDEIVKALLIKG 96 Query: 306 AAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 A V N +G T + A N+ E+ +L Sbjct: 97 AQVNAVNQNGCTALHYAASKNRHEIAVML 125 Score = 54.3 bits (129), Expect = 3e-07 Identities = 36/106 (33%), Positives = 51/106 (48%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMD 385 +H S G E ++ L G +E+D G LH A G + + LL GA V+A++ Sbjct: 44 LHWACSAGHTEIVEFLLQLGVPVNEKDDAGWSPLHIAASAGRDEIVKALLIKGAQVNAVN 103 Query: 384 KNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLN 247 +N T LHYAA R E +LL+ GA N D K D ++ Sbjct: 104 QNGCTALHYAASKNRHEIAVMLLEGGA-----NPDAKNHYDATAMH 144 Score = 38.9 bits (89), Expect = 0.014 Identities = 22/72 (30%), Positives = 38/72 (52%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMD 385 +H A+ G+ + + L A + +D+EG LH AC + A++L+ GA++ + Sbjct: 143 MHRAAAKGNLKMVHILLFYKASTNIQDTEGNTPLHLACDEERVEEAKLLVTQGASIYIEN 202 Query: 384 KNKNTPLHYAAG 349 K + TPL A G Sbjct: 203 KEEKTPLQVAKG 214
>ANK1_MOUSE (Q02357) Ankyrin-1 (Erythrocyte ankyrin)| Length = 1862 Score = 65.9 bits (159), Expect = 1e-10 Identities = 41/115 (35%), Positives = 57/115 (49%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMD 385 +H A +G +K L+ GA + + G LH A G A LLE A+ M Sbjct: 470 LHCAARIGHTGMVKLLLENGASPNLATTAGHTPLHTAAREGHVDTALALLEKEASQACMT 529 Query: 384 KNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 K TPLH AA YG+ +LLL+H A +G TP+ VA +N +++KLL Sbjct: 530 KKGFTPLHVAAKYGKVRLAELLLEHDAHPNAAGKNGLTPLHVAVHHNNLDIVKLL 584 Score = 65.9 bits (159), Expect = 1e-10 Identities = 43/143 (30%), Positives = 68/143 (47%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMD 385 +H A G K LD GA + G LH AC + E+LL+ GA++DA+ Sbjct: 338 LHVAAHCGHHRVAKVLLDKGAKPNSRALNGFTPLHIACKKNHIRVMELLLKTGASIDAVT 397 Query: 384 KNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLLEKDVF 205 ++ TPLH A+ G V LL+ GA+ + N+ +TP+ +A EV K L ++ Sbjct: 398 ESGLTPLHVASFMGHLPIVKNLLQRGASPNVSNVKVETPLHMAARAGHTEVAKYLLQNKA 457 Query: 204 L*IASLGSHEETWPSSCFTSLWH 136 A+ + ++ P C + H Sbjct: 458 K--ANAKAKDDQTPLHCAARIGH 478 Score = 58.9 bits (141), Expect = 1e-08 Identities = 39/115 (33%), Positives = 55/115 (47%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMD 385 +H A G + L+ A + +G LH A YG+ + AE+LLE A +A Sbjct: 503 LHTAAREGHVDTALALLEKEASQACMTKKGFTPLHVAAKYGKVRLAELLLEHDAHPNAAG 562 Query: 384 KNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 KN TPLH A + + V LLL G + +G TP+ +A NQ EV + L Sbjct: 563 KNGLTPLHVAVHHNNLDIVKLLLPRGGSPHSPAWNGYTPLHIAAKQNQIEVARSL 617 Score = 58.2 bits (139), Expect = 2e-08 Identities = 40/119 (33%), Positives = 59/119 (49%), Gaps = 1/119 (0%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMD 385 +H + +G +K L GA + + + LH A G + A+ LL+ A +A Sbjct: 404 LHVASFMGHLPIVKNLLQRGASPNVSNVKVETPLHMAARAGHTEVAKYLLQNKAKANAKA 463 Query: 384 KNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPI-DVAKLNNQDEVLKLLEKD 211 K+ TPLH AA G V LLL++GA+ L G TP+ A+ + D L LLEK+ Sbjct: 464 KDDQTPLHCAARIGHTGMVKLLLENGASPNLATTAGHTPLHTAAREGHVDTALALLEKE 522 Score = 58.2 bits (139), Expect = 2e-08 Identities = 37/115 (32%), Positives = 57/115 (49%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMD 385 +H + G+ ++ LD GA + + LH A G + +EILL+ GA + A Sbjct: 239 LHIASRRGNVIMVRLLLDRGAQIETRTKDELTPLHCAARNGHVRISEILLDHGAPIQAKT 298 Query: 384 KNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 KN +P+H AA +CV LLL++ A + +D TP+ VA V K+L Sbjct: 299 KNGLSPIHMAAQGDHLDCVRLLLQYNAEIDDITLDHLTPLHVAAHCGHHRVAKVL 353 Score = 56.6 bits (135), Expect = 6e-08 Identities = 39/120 (32%), Positives = 60/120 (50%), Gaps = 3/120 (2%) Frame = -1 Query: 507 GADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECV 328 G D G LH A YG K + LL+ A V+A K +PLH AA G + V Sbjct: 687 GVTVDATTRMGYTPLHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQGHTDIV 746 Query: 327 DLLLKHGAAVTLQNMDGKTPIDVAK---LNNQDEVLKLLEKDVFL*IASLGSHEETWPSS 157 LLLK+GA+ + +G TP+ +AK + +VLK++ + + + S H ++P + Sbjct: 747 TLLLKNGASPNEVSSNGTTPLAIAKRLGYISVTDVLKVVTDETSVVLVS-DKHRMSYPET 805 Score = 55.5 bits (132), Expect = 1e-07 Identities = 35/118 (29%), Positives = 55/118 (46%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMD 385 +H A G E + L A+ + + G LH G A++L++ G VDA Sbjct: 635 LHLAAQEGHTEMVALLLSKQANGNLGNKSGLTPLHLVSQEGHVPVADVLIKHGVTVDATT 694 Query: 384 KNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLLEKD 211 + TPLH A+ YG + V LL+H A V + G +P+ A +++ LL K+ Sbjct: 695 RMGYTPLHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQGHTDIVTLLLKN 752 Score = 55.5 bits (132), Expect = 1e-07 Identities = 39/106 (36%), Positives = 50/106 (47%), Gaps = 3/106 (2%) Frame = -1 Query: 528 LKKALD---GGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHY 358 L KALD G D + + G LH A G K LL ++ K NT LH Sbjct: 21 LDKALDHLRNGVDINTCNQNGLNGLHLASKEGHVKMVVELLHKEIILETTTKKGNTALHI 80 Query: 357 AAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 AA G+ E V L+ +GA V Q+ G TP+ +A N EV+K L Sbjct: 81 AALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFL 126 Score = 54.7 bits (130), Expect = 2e-07 Identities = 31/99 (31%), Positives = 50/99 (50%) Frame = -1 Query: 516 LDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRK 337 L+ GA + G LH A G +LL+ GA ++ K++ TPLH AA G Sbjct: 222 LNRGASVNFTPQNGITPLHIASRRGNVIMVRLLLDRGAQIETRTKDELTPLHCAARNGHV 281 Query: 336 ECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 ++LL HGA + + +G +PI +A + + ++LL Sbjct: 282 RISEILLDHGAPIQAKTKNGLSPIHMAAQGDHLDCVRLL 320 Score = 53.9 bits (128), Expect = 4e-07 Identities = 32/101 (31%), Positives = 47/101 (46%) Frame = -1 Query: 516 LDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRK 337 LD GA + G +H A C +LL+ A +D + + TPLH AA G Sbjct: 288 LDHGAPIQAKTKNGLSPIHMAAQGDHLDCVRLLLQYNAEIDDITLDHLTPLHVAAHCGHH 347 Query: 336 ECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLLEK 214 +LL GA + ++G TP+ +A N V++LL K Sbjct: 348 RVAKVLLDKGAKPNSRALNGFTPLHIACKKNHIRVMELLLK 388 Score = 52.8 bits (125), Expect = 9e-07 Identities = 35/115 (30%), Positives = 49/115 (42%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMD 385 +H A D L + D G LH A Y A++LL GA+V+ Sbjct: 173 LHIAARNDDTRTAAVLLQNDPNPDVLSKTGFTPLHIAAHYENLNVAQLLLNRGASVNFTP 232 Query: 384 KNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 +N TPLH A+ G V LLL GA + + D TP+ A N + ++L Sbjct: 233 QNGITPLHIASRRGNVIMVRLLLDRGAQIETRTKDELTPLHCAARNGHVRISEIL 287 Score = 51.2 bits (121), Expect = 3e-06 Identities = 35/114 (30%), Positives = 55/114 (48%), Gaps = 1/114 (0%) Frame = -1 Query: 558 HTASVGDG-EGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDK 382 H A+ GD + ++ L A+ D+ + LH A G + A++LL+ GA ++ Sbjct: 306 HMAAQGDHLDCVRLLLQYNAEIDDITLDHLTPLHVAAHCGHHRVAKVLLDKGAKPNSRAL 365 Query: 381 NKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 N TPLH A ++LLLK GA++ G TP+ VA ++K L Sbjct: 366 NGFTPLHIACKKNHIRVMELLLKTGASIDAVTESGLTPLHVASFMGHLPIVKNL 419 Score = 50.1 bits (118), Expect = 6e-06 Identities = 33/115 (28%), Positives = 49/115 (42%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMD 385 +H A E + L G + E +G LH A G + +LL A + + Sbjct: 602 LHIAAKQNQIEVARSLLQYGGSANAESVQGVTPLHLAAQEGHTEMVALLLSKQANGNLGN 661 Query: 384 KNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 K+ TPLH + G D+L+KHG V G TP+ VA +++K L Sbjct: 662 KSGLTPLHLVSQEGHVPVADVLIKHGVTVDATTRMGYTPLHVASHYGNIKLVKFL 716 Score = 48.9 bits (115), Expect = 1e-05 Identities = 28/83 (33%), Positives = 40/83 (48%) Frame = -1 Query: 468 ALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQ 289 ALH A + + A +LL+ D + K TPLH AA Y LLL GA+V Sbjct: 172 ALHIAARNDDTRTAAVLLQNDPNPDVLSKTGFTPLHIAAHYENLNVAQLLLNRGASVNFT 231 Query: 288 NMDGKTPIDVAKLNNQDEVLKLL 220 +G TP+ +A +++LL Sbjct: 232 PQNGITPLHIASRRGNVIMVRLL 254 Score = 47.0 bits (110), Expect = 5e-05 Identities = 29/84 (34%), Positives = 42/84 (50%) Frame = -1 Query: 480 EGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLLKHGAA 301 +G ALH A G+ + L+ GA V+A + TPL+ AA E V LL++GA Sbjct: 73 KGNTALHIAALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFLLENGAN 132 Query: 300 VTLQNMDGKTPIDVAKLNNQDEVL 229 + DG TP+ VA + V+ Sbjct: 133 QNVATEDGFTPLAVALQQGHENVV 156 Score = 46.6 bits (109), Expect = 7e-05 Identities = 30/115 (26%), Positives = 50/115 (43%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMD 385 +H A G + L+ A + G LH A + ++LL G + + Sbjct: 536 LHVAAKYGKVRLAELLLEHDAHPNAAGKNGLTPLHVAVHHNNLDIVKLLLPRGGSPHSPA 595 Query: 384 KNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 N TPLH AA + E LL++G + +++ G TP+ +A E++ LL Sbjct: 596 WNGYTPLHIAAKQNQIEVARSLLQYGGSANAESVQGVTPLHLAAQEGHTEMVALL 650 Score = 45.4 bits (106), Expect = 1e-04 Identities = 33/105 (31%), Positives = 42/105 (40%) Frame = -1 Query: 528 LKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAG 349 +K L G G LH A + + A LL+ G + +A TPLH AA Sbjct: 581 VKLLLPRGGSPHSPAWNGYTPLHIAAKQNQIEVARSLLQYGGSANAESVQGVTPLHLAAQ 640 Query: 348 YGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLLEK 214 G E V LLL A L N G TP+ + V +L K Sbjct: 641 EGHTEMVALLLSKQANGNLGNKSGLTPLHLVSQEGHVPVADVLIK 685 Score = 45.4 bits (106), Expect = 1e-04 Identities = 33/115 (28%), Positives = 50/115 (43%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMD 385 +H A G E K L A + + + + LH A G ++LLE GA+ + Sbjct: 437 LHMAARAGHTEVAKYLLQNKAKANAKAKDDQTPLHCAARIGHTGMVKLLLENGASPNLAT 496 Query: 384 KNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 +TPLH AA G + LL+ A+ G TP+ VA + + +LL Sbjct: 497 TAGHTPLHTAAREGHVDTALALLEKEASQACMTKKGFTPLHVAAKYGKVRLAELL 551 Score = 36.2 bits (82), Expect = 0.091 Identities = 22/86 (25%), Positives = 41/86 (47%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMD 385 +H A G E +++ ++ GA+ + + +G L+ A + + LLE GA + Sbjct: 78 LHIAALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFLLENGANQNVAT 137 Query: 384 KNKNTPLHYAAGYGRKECVDLLLKHG 307 ++ TPL A G + V L+ +G Sbjct: 138 EDGFTPLAVALQQGHENVVAHLINYG 163
>EHMT1_HUMAN (Q9H9B1) Histone-lysine N-methyltransferase, H3 lysine-9 specific 5| (EC 2.1.1.43) (Histone H3-K9 methyltransferase 5) (H3-K9-HMTase 5) (Euchromatic histone-lysine N-methyltransferase 1) (Eu-HMTase1) (G9a-like protein 1) (GLP1) Length = 1267 Score = 65.9 bits (159), Expect = 1e-10 Identities = 38/96 (39%), Positives = 56/96 (58%) Frame = -1 Query: 528 LKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAG 349 +K L G+D + D+E LH+A G AEILL A + A++ + ++PLH AA Sbjct: 858 VKLLLSKGSDINIRDNEENICLHWAAFSGCVDIAEILLAAKCDLHAVNIHGDSPLHIAAR 917 Query: 348 YGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQ 241 R +CV L L + VTL+N +G+TP+ A LN+Q Sbjct: 918 ENRYDCVVLFLSRDSDVTLKNKEGETPLQCASLNSQ 953 Score = 48.1 bits (113), Expect = 2e-05 Identities = 29/90 (32%), Positives = 44/90 (48%) Frame = -1 Query: 489 EDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLLKH 310 E R LH A G +L++AGA +D +++ TPL AA E V L+K Sbjct: 738 EHQNKRSPLHAAAEAGHVDICHMLVQAGANIDTCSEDQRTPLMEAAENNHLEAVKYLIKA 797 Query: 309 GAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 GA V ++ +G T + +A EV++ L Sbjct: 798 GALVDPKDAEGSTCLHLAAKKGHYEVVQYL 827 Score = 45.1 bits (105), Expect = 2e-04 Identities = 28/106 (26%), Positives = 51/106 (48%), Gaps = 1/106 (0%) Frame = -1 Query: 534 EGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAA-VDAMDKNKNTPLHY 358 E +K + GA D +D+EG LH A G ++ + LL G V+ D TP+ + Sbjct: 789 EAVKYLIKAGALVDPKDAEGSTCLHLAAKKGHYEVVQYLLSNGQMDVNCQDDGGWTPMIW 848 Query: 357 AAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 A Y + V LLL G+ + +++ + + A + ++ ++L Sbjct: 849 ATEYKHVDLVKLLLSKGSDINIRDNEENICLHWAAFSGCVDIAEIL 894 Score = 41.2 bits (95), Expect = 0.003 Identities = 29/93 (31%), Positives = 47/93 (50%), Gaps = 7/93 (7%) Frame = -1 Query: 471 RALHFACGYGEFKCAEILLEAGAAVDAMD-------KNKNTPLHYAAGYGRKECVDLLLK 313 + L+F+ GE + ++L VD +D +NK +PLH AA G + +L++ Sbjct: 709 KQLYFSARQGELQKVLLML-----VDGIDPNFKMEHQNKRSPLHAAAEAGHVDICHMLVQ 763 Query: 312 HGAAVTLQNMDGKTPIDVAKLNNQDEVLKLLEK 214 GA + + D +TP+ A NN E +K L K Sbjct: 764 AGANIDTCSEDQRTPLMEAAENNHLEAVKYLIK 796
>BARD1_MOUSE (O70445) BRCA1-associated RING domain protein 1 (BARD-1)| Length = 765 Score = 65.9 bits (159), Expect = 1e-10 Identities = 40/117 (34%), Positives = 59/117 (50%), Gaps = 1/117 (0%) Frame = -1 Query: 558 HTASV-GDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDK 382 H AS+ GD ++ L G D + +D G LH AC +G K E+LL+ A V+ Sbjct: 421 HIASIKGDIPSVEYLLQNGNDPNVKDHAGWTPLHEACSHGHLKVVELLLQHNALVNTPGY 480 Query: 381 NKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLLEKD 211 ++PLH A G + V +LL HGA+ N+ G P+D N +L L E++ Sbjct: 481 QNDSPLHDAVKSGHIDIVKVLLSHGASRNAVNIFGVRPVDYTDNENIRSLLLLPEEN 537 Score = 49.3 bits (116), Expect = 1e-05 Identities = 29/99 (29%), Positives = 45/99 (45%) Frame = -1 Query: 516 LDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRK 337 L G + + G LH A G+ E LL+ G + D TPLH A +G Sbjct: 403 LSSGMPARKRNHRGETLLHIASIKGDIPSVEYLLQNGNDPNVKDHAGWTPLHEACSHGHL 462 Query: 336 ECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 + V+LLL+H A V +P+ A + +++K+L Sbjct: 463 KVVELLLQHNALVNTPGYQNDSPLHDAVKSGHIDIVKVL 501
>TNI3K_PONPY (Q5RF15) Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1)| (TNNI3-interacting kinase) Length = 617 Score = 65.5 bits (158), Expect = 1e-10 Identities = 41/118 (34%), Positives = 58/118 (49%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMD 385 +H + E + L GGAD + G ALH A G + A++LL+ GA V+ D Sbjct: 104 LHLAVYKDNAELITSLLHGGADIQQVGYGGLTALHIATIAGHLEAADVLLQHGANVNIQD 163 Query: 384 KNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLLEKD 211 TPLH AA YG ++ LLLK GA V + G P+ +A + KLL ++ Sbjct: 164 AVFFTPLHIAAYYGHEQVTRLLLKFGADVNVSGEVGDRPLHLASAKGFLNIAKLLMEE 221 Score = 47.4 bits (111), Expect = 4e-05 Identities = 30/88 (34%), Positives = 42/88 (47%) Frame = -1 Query: 477 GRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLLKHGAAV 298 G ALH A + LL GA + + T LH A G E D+LL+HGA V Sbjct: 100 GFTALHLAVYKDNAELITSLLHGGADIQQVGYGGLTALHIATIAGHLEAADVLLQHGANV 159 Query: 297 TLQNMDGKTPIDVAKLNNQDEVLKLLEK 214 +Q+ TP+ +A ++V +LL K Sbjct: 160 NIQDAVFFTPLHIAAYYGHEQVTRLLLK 187 Score = 44.7 bits (104), Expect = 3e-04 Identities = 34/122 (27%), Positives = 56/122 (45%), Gaps = 3/122 (2%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMD 385 +H G E L GA+ + +D+ LH A YG + +LL+ GA V+ Sbjct: 137 LHIATIAGHLEAADVLLQHGANVNIQDAVFFTPLHIAAYYGHEQVTRLLLKFGADVNVSG 196 Query: 384 KNKNTPLHYAAGYGRKECVDLLLKHG--AAVTLQNMDGKTPID-VAKLNNQDEVLKLLEK 214 + + PLH A+ G LL++ G A V Q+ + P+ ++ + D V LL+ Sbjct: 197 EVGDRPLHLASAKGFLNIAKLLMEEGSKADVNAQDNEDHVPLHFCSRFGHHDIVKYLLQN 256 Query: 213 DV 208 D+ Sbjct: 257 DL 258 Score = 30.0 bits (66), Expect = 6.5 Identities = 23/90 (25%), Positives = 38/90 (42%), Gaps = 4/90 (4%) Frame = -1 Query: 477 GRRALHFACGYGEFKCAEILLEAGAAVDAMDKN--KNTPLHYAAGYGRK-ECVDLLLKHG 307 G LH AC G+F+ A+ +++ +N T H A YG+ + V LL Sbjct: 269 GDTPLHLACYNGKFEVAKEIIQISGTESLTKENIFSETAFHSACTYGKSIDLVKFLLDQN 328 Query: 306 AA-VTLQNMDGKTPIDVAKLNNQDEVLKLL 220 + Q DG T + A + +++ L Sbjct: 329 VININHQGRDGHTGLHSACYHGHIHLVQFL 358
>MIB1_BRARE (Q804S5) Ubiquitin ligase protein mib (EC 6.3.2.-) (Mind bomb| protein) Length = 1030 Score = 65.5 bits (158), Expect = 1e-10 Identities = 38/108 (35%), Positives = 56/108 (51%) Frame = -1 Query: 543 GDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPL 364 G + LK L D + ED +G RA+H A E E+L GA ++A +K + TPL Sbjct: 475 GHVDVLKLLLKHSVDLEAEDKDGDRAVHHASFGDEGSVIEVLHRGGADLNARNKRRQTPL 534 Query: 363 HYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 H A G + V LL G +LQ+ +G TP+ A +D++L +L Sbjct: 535 HIAVNKGHLQVVKTLLDFGCHPSLQDSEGDTPLHDAISKKRDDMLSVL 582 Score = 57.8 bits (138), Expect = 3e-08 Identities = 33/115 (28%), Positives = 54/115 (46%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMD 385 VHH + +G ++ GGAD + + + LH A G + + LL+ G D Sbjct: 501 VHHASFGDEGSVIEVLHRGGADLNARNKRRQTPLHIAVNKGHLQVVKTLLDFGCHPSLQD 560 Query: 384 KNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 +TPLH A R + + +LL+ GA VT+ N +G + A L +++L Sbjct: 561 SEGDTPLHDAISKKRDDMLSVLLEAGADVTITNNNGFNALHHAALRGNPSAMRVL 615 Score = 52.4 bits (124), Expect = 1e-06 Identities = 40/118 (33%), Positives = 54/118 (45%), Gaps = 3/118 (2%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMD 385 +H + G + +K LD G +DSEG LH A +LLEAGA V + Sbjct: 534 LHIAVNKGHLQVVKTLLDFGCHPSLQDSEGDTPLHDAISKKRDDMLSVLLEAGADVTITN 593 Query: 384 KNKNTPLHYAAGYGRKECVDLLLK---HGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 N LH+AA G + +LL V + DG T + +A LNN EV +LL Sbjct: 594 NNGFNALHHAALRGNPSAMRVLLSKLPRPWIVDEKKDDGYTALHLAALNNHVEVAELL 651 Score = 48.1 bits (113), Expect = 2e-05 Identities = 35/120 (29%), Positives = 58/120 (48%), Gaps = 4/120 (3%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADK---DEEDSEGRRALHFACGYGEFKCAEILLEAG-AAV 397 +HH A G+ ++ L DE+ +G ALH A + AE+L+ G A + Sbjct: 600 LHHAALRGNPSAMRVLLSKLPRPWIVDEKKDDGYTALHLAALNNHVEVAELLVHQGNANL 659 Query: 396 DAMDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLLE 217 D + N+ T LH A + V LL++ A + +Q+ DG TP+ A ++ L+ L+ Sbjct: 660 DVQNVNQQTALHLAVERQHTQIVRLLVRAEAKLDVQDKDGDTPLHEALRHHTLSQLRQLQ 719 Score = 36.2 bits (82), Expect = 0.091 Identities = 21/86 (24%), Positives = 43/86 (50%) Frame = -1 Query: 477 GRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLLKHGAAV 298 G A+ A G ++LL+ ++A DK+ + +H+A+ +++L + GA + Sbjct: 464 GHTAMQAASQNGHVDVLKLLLKHSVDLEAEDKDGDRAVHHASFGDEGSVIEVLHRGGADL 523 Query: 297 TLQNMDGKTPIDVAKLNNQDEVLKLL 220 +N +TP+ +A +V+K L Sbjct: 524 NARNKRRQTPLHIAVNKGHLQVVKTL 549
>MIB_DROME (Q9VUX2) Ubiquitin ligase protein mind-bomb (EC 6.3.2.-) (Mind bomb| homolog) (D-mib) Length = 1226 Score = 65.5 bits (158), Expect = 1e-10 Identities = 44/139 (31%), Positives = 64/139 (46%) Frame = -1 Query: 636 TVSTAEPSXXXXXXXXXXXXXESIVHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHF 457 + S+A PS + + + G E ++ L D + ED +G RA+H Sbjct: 548 STSSASPSSGPDVNVNGVFAGHTALQAASQNGHIEVIQVLLRHAVDVEIEDKDGDRAVHH 607 Query: 456 ACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDG 277 A E EIL +AGA ++A +K + T LH A G V LL G +LQ+ +G Sbjct: 608 AAFGDEAAVIEILAKAGADLNARNKRRQTSLHIAVNKGHLNVVKTLLTLGCHPSLQDSEG 667 Query: 276 KTPIDVAKLNNQDEVLKLL 220 TP+ A DE+L LL Sbjct: 668 DTPLHDAISKEHDEMLSLL 686 Score = 56.6 bits (135), Expect = 6e-08 Identities = 34/115 (29%), Positives = 49/115 (42%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMD 385 VHH A + ++ GAD + + + +LH A G + LL G D Sbjct: 605 VHHAAFGDEAAVIEILAKAGADLNARNKRRQTSLHIAVNKGHLNVVKTLLTLGCHPSLQD 664 Query: 384 KNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 +TPLH A E + LLL GA +TL N +G + A L +K+L Sbjct: 665 SEGDTPLHDAISKEHDEMLSLLLDFGADITLNNNNGFNALHHAALKGNPSAMKIL 719 Score = 41.6 bits (96), Expect = 0.002 Identities = 37/122 (30%), Positives = 57/122 (46%), Gaps = 4/122 (3%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMD 385 +H S E L LD GAD ++ G ALH A G +ILL ++ Sbjct: 671 LHDAISKEHDEMLSLLLDFGADITLNNNNGFNALHHAALKGNPSAMKILLTKTNRPWIVE 730 Query: 384 KNKN---TPLHYAAGYGRKECVDLLLKHGAA-VTLQNMDGKTPIDVAKLNNQDEVLKLLE 217 + K+ T LH AA E +LL+ G A + QN++ +T + +A +++KLL Sbjct: 731 EKKDDGYTALHLAALNNHVEIAELLVHMGKANMDRQNVNLQTALHLAVERQHVQIVKLLV 790 Query: 216 KD 211 +D Sbjct: 791 QD 792 Score = 35.8 bits (81), Expect = 0.12 Identities = 28/113 (24%), Positives = 49/113 (43%), Gaps = 29/113 (25%) Frame = -1 Query: 510 GGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYA-------- 355 G A+ D ++ + ALH A + ++L++ GA ++ DK+ +TPLH A Sbjct: 759 GKANMDRQNVNLQTALHLAVERQHVQIVKLLVQDGADLNIPDKDGDTPLHEALRHHTLSQ 818 Query: 354 -------AGYGR--------------KECVDLLLKHGAAVTLQNMDGKTPIDV 259 G+G+ L +GA +TL+N +TP+D+ Sbjct: 819 LKQLQDVEGFGKLLMGLRNANNKKASASIACFLAANGADLTLKNRKQQTPLDL 871
>AKIB1_HUMAN (Q9P2G1) Ankyrin repeat and IBR domain-containing protein 1| (Fragment) Length = 1214 Score = 65.5 bits (158), Expect = 1e-10 Identities = 34/68 (50%), Positives = 45/68 (66%), Gaps = 1/68 (1%) Frame = -1 Query: 405 AAVDAMDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVA-KLNNQDEVL 229 AA+DA+D KNTPLHYAA G K CV+LL+KHG + +N + TP D A K +++D L Sbjct: 261 AAIDAVDNKKNTPLHYAAASGMKACVELLVKHGGDLFAENENKDTPCDCAEKQHHKDLAL 320 Query: 228 KLLEKDVF 205 L + VF Sbjct: 321 NLESQMVF 328 Score = 35.0 bits (79), Expect = 0.20 Identities = 31/137 (22%), Positives = 55/137 (40%), Gaps = 18/137 (13%) Frame = -1 Query: 495 DEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRK------- 337 D D++ LH+A G C E+L++ G + A ++NK+TP A K Sbjct: 264 DAVDNKKNTPLHYAAASGMKACVELLVKHGGDLFAENENKDTPCDCAEKQHHKDLALNLE 323 Query: 336 ---------ECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQ--DEVLKLLEKDVFL*IAS 190 E ++ ++ A + +G P D+ +L + E +L+ +F A Sbjct: 324 SQMVFSRDPEAEEIEAEYAALDKREPYEGLRPQDLRRLKDMLIVETADMLQAPLFTAEAL 383 Query: 189 LGSHEETWPSSCFTSLW 139 L +H+ W W Sbjct: 384 LRAHD--WDREKLLEAW 398
>AKIB1_MOUSE (Q6ZPS6) Ankyrin repeat and IBR domain-containing protein 1| (Fragment) Length = 1087 Score = 65.1 bits (157), Expect = 2e-10 Identities = 34/68 (50%), Positives = 44/68 (64%), Gaps = 1/68 (1%) Frame = -1 Query: 405 AAVDAMDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVA-KLNNQDEVL 229 AA+DA+D KNTPLHYAA G K CV+LL+KHG + +N + TP D A K ++D L Sbjct: 139 AAIDAVDNKKNTPLHYAAASGMKACVELLVKHGGDLFAENENRDTPCDCAEKQQHKDLAL 198 Query: 228 KLLEKDVF 205 L + VF Sbjct: 199 SLESQMVF 206 Score = 33.9 bits (76), Expect = 0.45 Identities = 30/137 (21%), Positives = 55/137 (40%), Gaps = 18/137 (13%) Frame = -1 Query: 495 DEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRK------- 337 D D++ LH+A G C E+L++ G + A ++N++TP A K Sbjct: 142 DAVDNKKNTPLHYAAASGMKACVELLVKHGGDLFAENENRDTPCDCAEKQQHKDLALSLE 201 Query: 336 ---------ECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQ--DEVLKLLEKDVFL*IAS 190 E ++ ++ A + +G P D+ +L + E +L+ +F A Sbjct: 202 SQMVFSRDPEAEEIEAEYAALDKREPYEGLRPQDLRRLKDMLIVETADMLQAPLFTAEAL 261 Query: 189 LGSHEETWPSSCFTSLW 139 L +H+ W W Sbjct: 262 LRAHD--WDREKLLEAW 276
>ANK1_HUMAN (P16157) Ankyrin-1 (Erythrocyte ankyrin) (Ankyrin-R)| Length = 1880 Score = 65.1 bits (157), Expect = 2e-10 Identities = 39/115 (33%), Positives = 57/115 (49%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMD 385 +H A G K LD GA + G LH AC + E+LL+ GA++DA+ Sbjct: 341 LHVAAHCGHHRVAKVLLDKGAKPNSRALNGFTPLHIACKKNHVRVMELLLKTGASIDAVT 400 Query: 384 KNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 ++ TPLH A+ G V LL+ GA+ + N+ +TP+ +A EV K L Sbjct: 401 ESGLTPLHVASFMGHLPIVKNLLQRGASPNVSNVKVETPLHMAARAGHTEVAKYL 455 Score = 61.6 bits (148), Expect = 2e-09 Identities = 38/115 (33%), Positives = 56/115 (48%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMD 385 +H A +G +K L+ A+ + + G LH A G + LLE A+ M Sbjct: 473 LHCAARIGHTNMVKLLLENNANPNLATTAGHTPLHIAAREGHVETVLALLEKEASQACMT 532 Query: 384 KNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 K TPLH AA YG+ +LLL+ A +G TP+ VA +N +++KLL Sbjct: 533 KKGFTPLHVAAKYGKVRVAELLLERDAHPNAAGKNGLTPLHVAVHHNNLDIVKLL 587 Score = 60.8 bits (146), Expect = 3e-09 Identities = 40/115 (34%), Positives = 56/115 (48%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMD 385 +H A G E + L+ A + +G LH A YG+ + AE+LLE A +A Sbjct: 506 LHIAAREGHVETVLALLEKEASQACMTKKGFTPLHVAAKYGKVRVAELLLERDAHPNAAG 565 Query: 384 KNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 KN TPLH A + + V LLL G + +G TP+ +A NQ EV + L Sbjct: 566 KNGLTPLHVAVHHNNLDIVKLLLPRGGSPHSPAWNGYTPLHIAAKQNQVEVARSL 620 Score = 58.2 bits (139), Expect = 2e-08 Identities = 40/119 (33%), Positives = 60/119 (50%), Gaps = 1/119 (0%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMD 385 +H + +G +K L GA + + + LH A G + A+ LL+ A V+A Sbjct: 407 LHVASFMGHLPIVKNLLQRGASPNVSNVKVETPLHMAARAGHTEVAKYLLQNKAKVNAKA 466 Query: 384 KNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDV-AKLNNQDEVLKLLEKD 211 K+ TPLH AA G V LLL++ A L G TP+ + A+ + + VL LLEK+ Sbjct: 467 KDDQTPLHCAARIGHTNMVKLLLENNANPNLATTAGHTPLHIAAREGHVETVLALLEKE 525 Score = 58.2 bits (139), Expect = 2e-08 Identities = 37/115 (32%), Positives = 58/115 (50%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMD 385 +H + G+ ++ LD GA + + + LH A G + +EILL+ GA + A Sbjct: 242 LHIASRRGNVIMVRLLLDRGAQIETKTKDELTPLHCAARNGHVRISEILLDHGAPIQAKT 301 Query: 384 KNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 KN +P+H AA +CV LLL++ A + +D TP+ VA V K+L Sbjct: 302 KNGLSPIHMAAQGDHLDCVRLLLQYDAEIDDITLDHLTPLHVAAHCGHHRVAKVL 356 Score = 57.0 bits (136), Expect = 5e-08 Identities = 34/85 (40%), Positives = 44/85 (51%) Frame = -1 Query: 507 GADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECV 328 G D G LH A YG K + LL+ A V+A K +PLH AA G + V Sbjct: 690 GVMVDATTRMGYTPLHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQGHTDIV 749 Query: 327 DLLLKHGAAVTLQNMDGKTPIDVAK 253 LLLK+GA+ + DG TP+ +AK Sbjct: 750 TLLLKNGASPNEVSSDGTTPLAIAK 774 Score = 56.2 bits (134), Expect = 8e-08 Identities = 35/118 (29%), Positives = 55/118 (46%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMD 385 +H A G E + L A+ + + G LH G A++L++ G VDA Sbjct: 638 LHLAAQEGHAEMVALLLSKQANGNLGNKSGLTPLHLVAQEGHVPVADVLIKHGVMVDATT 697 Query: 384 KNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLLEKD 211 + TPLH A+ YG + V LL+H A V + G +P+ A +++ LL K+ Sbjct: 698 RMGYTPLHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQGHTDIVTLLLKN 755 Score = 55.5 bits (132), Expect = 1e-07 Identities = 39/106 (36%), Positives = 50/106 (47%), Gaps = 3/106 (2%) Frame = -1 Query: 528 LKKALD---GGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHY 358 L KALD G D + + G LH A G K LL ++ K NT LH Sbjct: 24 LDKALDHLRNGVDINTCNQNGLNGLHLASKEGHVKMVVELLHKEIILETTTKKGNTALHI 83 Query: 357 AAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 AA G+ E V L+ +GA V Q+ G TP+ +A N EV+K L Sbjct: 84 AALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFL 129 Score = 54.7 bits (130), Expect = 2e-07 Identities = 31/99 (31%), Positives = 50/99 (50%) Frame = -1 Query: 516 LDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRK 337 L+ GA + G LH A G +LL+ GA ++ K++ TPLH AA G Sbjct: 225 LNRGASVNFTPQNGITPLHIASRRGNVIMVRLLLDRGAQIETKTKDELTPLHCAARNGHV 284 Query: 336 ECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 ++LL HGA + + +G +PI +A + + ++LL Sbjct: 285 RISEILLDHGAPIQAKTKNGLSPIHMAAQGDHLDCVRLL 323 Score = 53.5 bits (127), Expect = 5e-07 Identities = 32/101 (31%), Positives = 47/101 (46%) Frame = -1 Query: 516 LDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRK 337 LD GA + G +H A C +LL+ A +D + + TPLH AA G Sbjct: 291 LDHGAPIQAKTKNGLSPIHMAAQGDHLDCVRLLLQYDAEIDDITLDHLTPLHVAAHCGHH 350 Query: 336 ECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLLEK 214 +LL GA + ++G TP+ +A N V++LL K Sbjct: 351 RVAKVLLDKGAKPNSRALNGFTPLHIACKKNHVRVMELLLK 391 Score = 52.8 bits (125), Expect = 9e-07 Identities = 35/115 (30%), Positives = 49/115 (42%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMD 385 +H A D L + D G LH A Y A++LL GA+V+ Sbjct: 176 LHIAARNDDTRTAAVLLQNDPNPDVLSKTGFTPLHIAAHYENLNVAQLLLNRGASVNFTP 235 Query: 384 KNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 +N TPLH A+ G V LLL GA + + D TP+ A N + ++L Sbjct: 236 QNGITPLHIASRRGNVIMVRLLLDRGAQIETKTKDELTPLHCAARNGHVRISEIL 290 Score = 51.2 bits (121), Expect = 3e-06 Identities = 34/115 (29%), Positives = 49/115 (42%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMD 385 +H A E + L G + E +G LH A G + +LL A + + Sbjct: 605 LHIAAKQNQVEVARSLLQYGGSANAESVQGVTPLHLAAQEGHAEMVALLLSKQANGNLGN 664 Query: 384 KNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 K+ TPLH A G D+L+KHG V G TP+ VA +++K L Sbjct: 665 KSGLTPLHLVAQEGHVPVADVLIKHGVMVDATTRMGYTPLHVASHYGNIKLVKFL 719 Score = 51.2 bits (121), Expect = 3e-06 Identities = 35/114 (30%), Positives = 55/114 (48%), Gaps = 1/114 (0%) Frame = -1 Query: 558 HTASVGDG-EGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDK 382 H A+ GD + ++ L A+ D+ + LH A G + A++LL+ GA ++ Sbjct: 309 HMAAQGDHLDCVRLLLQYDAEIDDITLDHLTPLHVAAHCGHHRVAKVLLDKGAKPNSRAL 368 Query: 381 NKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 N TPLH A ++LLLK GA++ G TP+ VA ++K L Sbjct: 369 NGFTPLHIACKKNHVRVMELLLKTGASIDAVTESGLTPLHVASFMGHLPIVKNL 422 Score = 48.9 bits (115), Expect = 1e-05 Identities = 28/83 (33%), Positives = 40/83 (48%) Frame = -1 Query: 468 ALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQ 289 ALH A + + A +LL+ D + K TPLH AA Y LLL GA+V Sbjct: 175 ALHIAARNDDTRTAAVLLQNDPNPDVLSKTGFTPLHIAAHYENLNVAQLLLNRGASVNFT 234 Query: 288 NMDGKTPIDVAKLNNQDEVLKLL 220 +G TP+ +A +++LL Sbjct: 235 PQNGITPLHIASRRGNVIMVRLL 257 Score = 47.0 bits (110), Expect = 5e-05 Identities = 30/115 (26%), Positives = 50/115 (43%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMD 385 +H A G + L+ A + G LH A + ++LL G + + Sbjct: 539 LHVAAKYGKVRVAELLLERDAHPNAAGKNGLTPLHVAVHHNNLDIVKLLLPRGGSPHSPA 598 Query: 384 KNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 N TPLH AA + E LL++G + +++ G TP+ +A E++ LL Sbjct: 599 WNGYTPLHIAAKQNQVEVARSLLQYGGSANAESVQGVTPLHLAAQEGHAEMVALL 653 Score = 47.0 bits (110), Expect = 5e-05 Identities = 37/119 (31%), Positives = 52/119 (43%), Gaps = 1/119 (0%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMD 385 +H A G E K L A + + + + LH A G ++LLE A + Sbjct: 440 LHMAARAGHTEVAKYLLQNKAKVNAKAKDDQTPLHCAARIGHTNMVKLLLENNANPNLAT 499 Query: 384 KNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLK-LLEKD 211 +TPLH AA G E V LL+ A+ G TP+ VA + V + LLE+D Sbjct: 500 TAGHTPLHIAAREGHVETVLALLEKEASQACMTKKGFTPLHVAAKYGKVRVAELLLERD 558 Score = 47.0 bits (110), Expect = 5e-05 Identities = 29/84 (34%), Positives = 42/84 (50%) Frame = -1 Query: 480 EGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLLKHGAA 301 +G ALH A G+ + L+ GA V+A + TPL+ AA E V LL++GA Sbjct: 76 KGNTALHIAALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFLLENGAN 135 Query: 300 VTLQNMDGKTPIDVAKLNNQDEVL 229 + DG TP+ VA + V+ Sbjct: 136 QNVATEDGFTPLAVALQQGHENVV 159 Score = 44.7 bits (104), Expect = 3e-04 Identities = 33/105 (31%), Positives = 42/105 (40%) Frame = -1 Query: 528 LKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAG 349 +K L G G LH A + + A LL+ G + +A TPLH AA Sbjct: 584 VKLLLPRGGSPHSPAWNGYTPLHIAAKQNQVEVARSLLQYGGSANAESVQGVTPLHLAAQ 643 Query: 348 YGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLLEK 214 G E V LLL A L N G TP+ + V +L K Sbjct: 644 EGHAEMVALLLSKQANGNLGNKSGLTPLHLVAQEGHVPVADVLIK 688 Score = 36.2 bits (82), Expect = 0.091 Identities = 22/86 (25%), Positives = 41/86 (47%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMD 385 +H A G E +++ ++ GA+ + + +G L+ A + + LLE GA + Sbjct: 81 LHIAALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFLLENGANQNVAT 140 Query: 384 KNKNTPLHYAAGYGRKECVDLLLKHG 307 ++ TPL A G + V L+ +G Sbjct: 141 EDGFTPLAVALQQGHENVVAHLINYG 166
>CTTB2_OTOGA (Q2QLG9) Cortactin-binding protein 2 (CortBP2)| Length = 1655 Score = 65.1 bits (157), Expect = 2e-10 Identities = 38/96 (39%), Positives = 52/96 (54%) Frame = -1 Query: 507 GADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECV 328 G D + +G AL+ A G C +LL A A V+A DKN TPL AA G ECV Sbjct: 725 GLDINYSCEDGHSALYSAAKNGHTDCVRLLLNAEAQVNAADKNGFTPLCAAAAQGHFECV 784 Query: 327 DLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 +LL+ + A + +G+TP+ +A N E +KLL Sbjct: 785 ELLIAYDAHINHAADEGQTPLYLACKNGNKECIKLL 820 Score = 57.8 bits (138), Expect = 3e-08 Identities = 35/117 (29%), Positives = 54/117 (46%) Frame = -1 Query: 570 SIVHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDA 391 S ++ A G + ++ L+ A + D G L A G F+C E+L+ A ++ Sbjct: 737 SALYSAAKNGHTDCVRLLLNAEAQVNAADKNGFTPLCAAAAQGHFECVELLIAYDAHINH 796 Query: 390 MDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 TPL+ A G KEC+ LLL+ G ++ DG TP+ + LKLL Sbjct: 797 AADEGQTPLYLACKNGNKECIKLLLEAGTNRNVKTRDGWTPVHAVVDTGDVDSLKLL 853 Score = 42.4 bits (98), Expect = 0.001 Identities = 26/92 (28%), Positives = 47/92 (51%), Gaps = 1/92 (1%) Frame = -1 Query: 480 EGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLLKHGAA 301 EG+ L+ AC G +C ++LLEAG + ++ TP+H G + + LL+ H A Sbjct: 800 EGQTPLYLACKNGNKECIKLLLEAGTNRNVKTRDGWTPVHAVVDTGDVDSLKLLMYHRAP 859 Query: 300 VTLQNMDGKTP-IDVAKLNNQDEVLKLLEKDV 208 +++ + P D+ L+ +E + + K V Sbjct: 860 ARGNSLNEEEPKSDIFDLDEGEESPEGISKPV 891 Score = 33.9 bits (76), Expect = 0.45 Identities = 21/68 (30%), Positives = 35/68 (51%) Frame = -1 Query: 423 ILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNN 244 +L E G ++ ++ ++ L+ AA G +CV LLL A V + +G TP+ A Sbjct: 720 LLNEEGLDINYSCEDGHSALYSAAKNGHTDCVRLLLNAEAQVNAADKNGFTPLCAAAAQG 779 Query: 243 QDEVLKLL 220 E ++LL Sbjct: 780 HFECVELL 787
>ANKR5_HUMAN (Q9NU02) Ankyrin repeat domain-containing protein 5| Length = 776 Score = 65.1 bits (157), Expect = 2e-10 Identities = 36/105 (34%), Positives = 57/105 (54%) Frame = -1 Query: 570 SIVHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDA 391 S ++ GD LKKA + G D +D+ + L AC G + LLE GA V+A Sbjct: 494 SNINIITKAGDLASLKKAFESGIPVDMKDNYYKTPLMTACASGNIDVVKFLLEKGANVNA 553 Query: 390 MDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVA 256 D TPLH+A G+++ V+LL++ GA + +++ TP++ A Sbjct: 554 TDNFLWTPLHFACHAGQQDIVELLVESGALIDAASINNSTPLNRA 598 Score = 62.8 bits (151), Expect = 9e-10 Identities = 38/110 (34%), Positives = 61/110 (55%) Frame = -1 Query: 543 GDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPL 364 G+ + +K L+ GA+ + D+ LHFAC G+ E+L+E+GA +DA N +TPL Sbjct: 536 GNIDVVKFLLEKGANVNATDNFLWTPLHFACHAGQQDIVELLVESGALIDAASINNSTPL 595 Query: 363 HYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLLEK 214 + A R + V LL GA L+N G + +DVAK ++ L+++ Sbjct: 596 NRAIESCRLDTVKYLLDIGAKFQLENRKGHSAMDVAKAYADYRIIDLIKE 645 Score = 56.2 bits (134), Expect = 8e-08 Identities = 32/94 (34%), Positives = 48/94 (51%) Frame = -1 Query: 534 EGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYA 355 E ++ L+ G + + D++ A HFA G F ++L V + N NTPLHYA Sbjct: 199 EIVRGILERGGEVNAFDNDRHHAAHFAAKGGFFDILKLLFAYNGDVGLISINGNTPLHYA 258 Query: 354 AGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAK 253 A G +C + + G + +N+D KTP VAK Sbjct: 259 AMGGFADCCKYIAQRGCDLKWKNLDHKTPRAVAK 292 Score = 42.4 bits (98), Expect = 0.001 Identities = 29/100 (29%), Positives = 49/100 (49%), Gaps = 1/100 (1%) Frame = -1 Query: 516 LDGGADKDE-EDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGR 340 L+ GA+ + S GR AL A G + +LE G V+A D +++ H+AA G Sbjct: 171 LEKGANPNAINSSTGRTALMEASREGVVEIVRGILERGGEVNAFDNDRHHAAHFAAKGGF 230 Query: 339 KECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 + + LL + V L +++G TP+ A + + K + Sbjct: 231 FDILKLLFAYNGDVGLISINGNTPLHYAAMGGFADCCKYI 270 Score = 34.7 bits (78), Expect = 0.26 Identities = 23/75 (30%), Positives = 34/75 (45%) Frame = -1 Query: 444 GEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPI 265 G+ + E+G VD D TPL A G + V LL+ GA V + TP+ Sbjct: 503 GDLASLKKAFESGIPVDMKDNYYKTPLMTACASGNIDVVKFLLEKGANVNATDNFLWTPL 562 Query: 264 DVAKLNNQDEVLKLL 220 A Q ++++LL Sbjct: 563 HFACHAGQQDIVELL 577
>LITD_LATMA (Q25338) Delta-latroinsectotoxin precursor (Delta-LIT)| Length = 1214 Score = 65.1 bits (157), Expect = 2e-10 Identities = 37/105 (35%), Positives = 58/105 (55%) Frame = -1 Query: 570 SIVHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDA 391 +++H S G +K+ L G++ +E+ EG +LH A E + A +L+E GA ++A Sbjct: 743 TVLHLAVSTGQINIIKELLKRGSNIEEKTGEGYTSLHIAAMRKEPEIAVVLIENGADIEA 802 Query: 390 MDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVA 256 + TPLH AA GRK V LL+ GA + + DG T + +A Sbjct: 803 RSADNLTPLHSAAKIGRKSTVLYLLEKGADIGAKTADGSTALHLA 847 Score = 45.8 bits (107), Expect = 1e-04 Identities = 31/103 (30%), Positives = 51/103 (49%), Gaps = 1/103 (0%) Frame = -1 Query: 516 LDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRK 337 ++ GAD + ++ LH A G LLE GA + A + +T LH A + Sbjct: 794 IENGADIEARSADNLTPLHSAAKIGRKSTVLYLLEKGADIGAKTADGSTALHLAVSGRKM 853 Query: 336 ECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKL-LEKD 211 + V+ LL GA + + + PI A +N+ ++++L LEKD Sbjct: 854 KTVETLLNKGANLKEYDNNKYLPIHKAIINDDLDMVRLFLEKD 896 Score = 43.9 bits (102), Expect = 4e-04 Identities = 24/70 (34%), Positives = 34/70 (48%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMD 385 +H A +G + L+ GAD + ++G ALH A + K E LL GA + D Sbjct: 811 LHSAAKIGRKSTVLYLLEKGADIGAKTADGSTALHLAVSGRKMKTVETLLNKGANLKEYD 870 Query: 384 KNKNTPLHYA 355 NK P+H A Sbjct: 871 NNKYLPIHKA 880 Score = 43.1 bits (100), Expect = 7e-04 Identities = 31/90 (34%), Positives = 45/90 (50%), Gaps = 3/90 (3%) Frame = -1 Query: 516 LDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKN--TPLHYAAGYG 343 ++ GAD + + R A+H G K A L ++D K+KN TPLH AA G Sbjct: 489 IEKGADIEAKFDNDRSAMHAVAYRGNNKIALRFLLKNQSIDIELKDKNGFTPLHIAAEAG 548 Query: 342 RKECVDLLLKHGAAVTLQ-NMDGKTPIDVA 256 + V LL+ HGA V + + TP+ +A Sbjct: 549 QAGFVKLLINHGADVNAKTSKTNLTPLHLA 578 Score = 37.7 bits (86), Expect = 0.031 Identities = 26/101 (25%), Positives = 49/101 (48%), Gaps = 4/101 (3%) Frame = -1 Query: 501 DKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDL 322 DK+ + + G H A + AE L+E+ A ++ D N P+H+AA G + + Sbjct: 630 DKNAQSTSGLTPFHLAIINESQEVAESLVESNADLNIQDVNHMAPIHFAASMGSIKMLRY 689 Query: 321 LLKHGAAVTLQNM---DGKTPIDVA-KLNNQDEVLKLLEKD 211 L+ V++ ++ + TP+ A +D +LL++D Sbjct: 690 LISIKDKVSINSVTENNNWTPLHFAIYFKKEDAAKELLKQD 730 Score = 31.6 bits (70), Expect = 2.2 Identities = 23/72 (31%), Positives = 38/72 (52%), Gaps = 2/72 (2%) Frame = -1 Query: 429 AEILLEAGAAVDAMDKNKNTPLHYAAGYGR-KECVDLLLKHGAA-VTLQNMDGKTPIDVA 256 A L+E GA ++A N + +H A G K + LLK+ + + L++ +G TP+ +A Sbjct: 485 ATTLIEKGADIEAKFDNDRSAMHAVAYRGNNKIALRFLLKNQSIDIELKDKNGFTPLHIA 544 Query: 255 KLNNQDEVLKLL 220 Q +KLL Sbjct: 545 AEAGQAGFVKLL 556
>V245_FOWPV (Q9J4Z5) Putative ankyrin repeat protein FPV245| Length = 436 Score = 64.7 bits (156), Expect = 2e-10 Identities = 37/117 (31%), Positives = 60/117 (51%) Frame = -1 Query: 570 SIVHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDA 391 + +H+ D E +K + GAD + +D G +H A ++ ++LLE GA + Sbjct: 126 TFLHYAIKNNDLEVIKMLFEYGADVNIKDDNGCYPIHIATRSNSYEIIKLLLEKGAYANV 185 Query: 390 MDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 D N+PLH AA YG C+ L+L H ++ + +G TP+ A L N+ V L+ Sbjct: 186 KDNYGNSPLHNAAKYGDYACIKLVLDHTNNISNKCNNGVTPLHNAILYNRSAVELLI 242 Score = 52.8 bits (125), Expect = 9e-07 Identities = 42/165 (25%), Positives = 72/165 (43%), Gaps = 33/165 (20%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMD 385 +H E +K L+ GA + +D+ G LH A YG++ C +++L+ + Sbjct: 161 IHIATRSNSYEIIKLLLEKGAYANVKDNYGNSPLHNAAKYGDYACIKLVLDHTNNISNKC 220 Query: 384 KNKNTPLHYAAGYGRK--------------------------------ECVDLLLKHGAA 301 N TPLH A Y R + +D+LL + A Sbjct: 221 NNGVTPLHNAILYNRSAVELLINNRSINDTDVDGYTPLHYALQPPCSIDIIDILLYNNAD 280 Query: 300 VTLQNMDGKTPIDVA-KLNNQDEVLKLLEKDVFL*IASLGSHEET 169 +++++ +G+ PID A K N+D V+K L + L I +G ++T Sbjct: 281 ISIKDNNGRNPIDTAFKYINRDSVIKELLANAVL-INEVGKLKDT 324 Score = 49.7 bits (117), Expect = 8e-06 Identities = 29/105 (27%), Positives = 52/105 (49%) Frame = -1 Query: 534 EGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYA 355 E +K LD G + ++++ + LH+A + + ++L E GA V+ D N P+H A Sbjct: 105 EMIKTILDSGVKVNTKNAKSKTFLHYAIKNNDLEVIKMLFEYGADVNIKDDNGCYPIHIA 164 Query: 354 AGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 E + LLL+ GA +++ G +P+ A +KL+ Sbjct: 165 TRSNSYEIIKLLLEKGAYANVKDNYGNSPLHNAAKYGDYACIKLV 209 Score = 32.0 bits (71), Expect = 1.7 Identities = 22/76 (28%), Positives = 35/76 (46%), Gaps = 1/76 (1%) Frame = -1 Query: 444 GEFKCAEILLE-AGAAVDAMDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTP 268 G+ E L++ G ++ + TPL A G + V+L +KHGA V N P Sbjct: 12 GDISLVEKLIKNKGNCINISVEETTTPLIDAIRTGNAKIVELFIKHGAQVNHVNTKIPNP 71 Query: 267 IDVAKLNNQDEVLKLL 220 + A +++KLL Sbjct: 72 LLTAIKIGSHDIVKLL 87
>ANKR2_HUMAN (Q9GZV1) Ankyrin repeat domain-containing protein 2 (Skeletal| muscle ankyrin repeat protein) (hArpp) Length = 333 Score = 64.7 bits (156), Expect = 2e-10 Identities = 38/115 (33%), Positives = 60/115 (52%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMD 385 +H + G E L+K LD GA D +D A+H+AC G + ++L GA + D Sbjct: 158 LHRASLEGHMEILEKLLDNGATVDFQDRLDCTAMHWACRGGHLEVVKLLQSHGADTNVRD 217 Query: 384 KNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 K +TPLH A G+ E V+ L G + ++ +G T + A N+ +++KLL Sbjct: 218 KLLSTPLHVAVRTGQVEIVEHFLSLGLEINARDREGDTALHDAVRLNRYKIIKLL 272 Score = 55.8 bits (133), Expect = 1e-07 Identities = 36/101 (35%), Positives = 50/101 (49%) Frame = -1 Query: 528 LKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAG 349 ++K L G D D R ALH A G + E LL+ GA VD D+ T +H+A Sbjct: 137 IEKFLADGGSADTCDQFRRTALHRASLEGHMEILEKLLDNGATVDFQDRLDCTAMHWACR 196 Query: 348 YGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLK 226 G E V LL HGA +++ TP+ VA Q E+++ Sbjct: 197 GGHLEVVKLLQSHGADTNVRDKLLSTPLHVAVRTGQVEIVE 237
>ACBD6_XENTR (Q66JD7) Acyl-CoA-binding domain-containing protein 6| Length = 286 Score = 64.3 bits (155), Expect = 3e-10 Identities = 40/113 (35%), Positives = 56/113 (49%) Frame = -1 Query: 510 GGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKEC 331 G D + D EGR LH+AC G + +LL A ++ D TPLHYA+ + Sbjct: 172 GAIDVNVADDEGRCLLHWACDRGHTQLVSVLLFHNAHINMQDSEGQTPLHYASACEFPDI 231 Query: 330 VDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLLEKDVFL*IASLGSHEE 172 VDLLL HGA +L + DG P +V N + +L++ AS G H + Sbjct: 232 VDLLLDHGADPSLVDNDGFQPHEVTDSKN---IAAMLQQH-----ASYGEHNK 276
>CTTB2_HUMAN (Q8WZ74) Cortactin-binding protein 2 (CortBP2)| Length = 1663 Score = 64.3 bits (155), Expect = 3e-10 Identities = 38/96 (39%), Positives = 51/96 (53%) Frame = -1 Query: 507 GADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECV 328 G D + +G AL+ A G C +LL A A V+A DKN TPL AA G ECV Sbjct: 734 GLDINYSCEDGHSALYSAAKNGHTDCVRLLLSAEAQVNAADKNGFTPLCAAAAQGHFECV 793 Query: 327 DLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 +LL+ + A + G+TP+ +A N E +KLL Sbjct: 794 ELLISYDANINHAADGGQTPLYLACKNGNKECIKLL 829 Score = 59.7 bits (143), Expect = 8e-09 Identities = 36/117 (30%), Positives = 55/117 (47%) Frame = -1 Query: 570 SIVHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDA 391 S ++ A G + ++ L A + D G L A G F+C E+L+ A ++ Sbjct: 746 SALYSAAKNGHTDCVRLLLSAEAQVNAADKNGFTPLCAAAAQGHFECVELLISYDANINH 805 Query: 390 MDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 TPL+ A G KEC+ LLL+ G +++ DG TP+ A + LKLL Sbjct: 806 AADGGQTPLYLACKNGNKECIKLLLEAGTNRSVKTTDGWTPVHAAVDTGNVDSLKLL 862 Score = 38.5 bits (88), Expect = 0.018 Identities = 23/81 (28%), Positives = 39/81 (48%) Frame = -1 Query: 552 ASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKN 373 A+ G E ++ + A+ + G+ L+ AC G +C ++LLEAG + Sbjct: 785 AAQGHFECVELLISYDANINHAADGGQTPLYLACKNGNKECIKLLLEAGTNRSVKTTDGW 844 Query: 372 TPLHYAAGYGRKECVDLLLKH 310 TP+H A G + + LL+ H Sbjct: 845 TPVHAAVDTGNVDSLKLLMYH 865 Score = 33.9 bits (76), Expect = 0.45 Identities = 21/68 (30%), Positives = 35/68 (51%) Frame = -1 Query: 423 ILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNN 244 +L E G ++ ++ ++ L+ AA G +CV LLL A V + +G TP+ A Sbjct: 729 LLNEEGLDINYSCEDGHSALYSAAKNGHTDCVRLLLSAEAQVNAADKNGFTPLCAAAAQG 788 Query: 243 QDEVLKLL 220 E ++LL Sbjct: 789 HFECVELL 796
>TNI3K_RAT (Q7TQP6) Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1)| (TNNI3-interacting kinase) (Cardiac ankyrin repeat kinase) Length = 834 Score = 63.9 bits (154), Expect = 4e-10 Identities = 39/108 (36%), Positives = 55/108 (50%) Frame = -1 Query: 534 EGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYA 355 E + L GAD + G ALH A G + AE+LL+ GA V+ D TPLH A Sbjct: 114 ELITSLLHSGADVQQVGYGGLTALHIAAIAGHPEAAEVLLQHGANVNVQDAVFFTPLHIA 173 Query: 354 AGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLLEKD 211 A YG ++ +LLK GA V + G P+ +A ++KLL ++ Sbjct: 174 AYYGHEQVTSVLLKFGADVNVSGEVGDRPLHLASAKGFFNIVKLLVEE 221 Score = 47.4 bits (111), Expect = 4e-05 Identities = 35/122 (28%), Positives = 59/122 (48%), Gaps = 3/122 (2%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMD 385 +H A G E + L GA+ + +D+ LH A YG + +LL+ GA V+ Sbjct: 137 LHIAAIAGHPEAAEVLLQHGANVNVQDAVFFTPLHIAAYYGHEQVTSVLLKFGADVNVSG 196 Query: 384 KNKNTPLHYAAGYGRKECVDLLLKHG--AAVTLQNMDGKTPID-VAKLNNQDEVLKLLEK 214 + + PLH A+ G V LL++ G A V Q+ + P+ ++ + + V LL+ Sbjct: 197 EVGDRPLHLASAKGFFNIVKLLVEEGSKADVNAQDNEDHVPLHFCSRFGHHNIVSYLLQS 256 Query: 213 DV 208 D+ Sbjct: 257 DL 258 Score = 45.1 bits (105), Expect = 2e-04 Identities = 30/88 (34%), Positives = 43/88 (48%) Frame = -1 Query: 477 GRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLLKHGAAV 298 G ALH A + LL +GA V + T LH AA G E ++LL+HGA V Sbjct: 100 GFPALHLAVYKDSPELITSLLHSGADVQQVGYGGLTALHIAAIAGHPEAAEVLLQHGANV 159 Query: 297 TLQNMDGKTPIDVAKLNNQDEVLKLLEK 214 +Q+ TP+ +A ++V +L K Sbjct: 160 NVQDAVFFTPLHIAAYYGHEQVTSVLLK 187
>CTTB2_MICMU (Q2QL82) Cortactin-binding protein 2 (CortBP2)| Length = 1647 Score = 63.9 bits (154), Expect = 4e-10 Identities = 38/96 (39%), Positives = 51/96 (53%) Frame = -1 Query: 507 GADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECV 328 G D + +G AL+ A G C +LL A A V+A DKN TPL AA G ECV Sbjct: 720 GLDINYSCEDGHSALYSAAKNGHTDCVRLLLNAEAQVNAADKNGFTPLCAAAAQGHFECV 779 Query: 327 DLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 +LL+ + A + G+TP+ +A N E +KLL Sbjct: 780 ELLIAYDANINHAADGGQTPLYLACKNGNKECIKLL 815 Score = 59.7 bits (143), Expect = 8e-09 Identities = 36/117 (30%), Positives = 56/117 (47%) Frame = -1 Query: 570 SIVHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDA 391 S ++ A G + ++ L+ A + D G L A G F+C E+L+ A ++ Sbjct: 732 SALYSAAKNGHTDCVRLLLNAEAQVNAADKNGFTPLCAAAAQGHFECVELLIAYDANINH 791 Query: 390 MDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 TPL+ A G KEC+ LLL+ G +++ DG TP+ A + LKLL Sbjct: 792 AADGGQTPLYLACKNGNKECIKLLLEAGTDRSVKTRDGWTPVHAAVDTGNVDSLKLL 848 Score = 43.1 bits (100), Expect = 7e-04 Identities = 25/82 (30%), Positives = 44/82 (53%), Gaps = 1/82 (1%) Frame = -1 Query: 477 GRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLLKHGAAV 298 G+ L+ AC G +C ++LLEAG ++ TP+H A G + + LL+ H A Sbjct: 796 GQTPLYLACKNGNKECIKLLLEAGTDRSVKTRDGWTPVHAAVDTGNVDSLKLLMYHRAPA 855 Query: 297 TLQNMDGKTP-IDVAKLNNQDE 235 +++ + P DV+ L++ +E Sbjct: 856 HGNSLNEEEPESDVSDLDDGEE 877 Score = 33.9 bits (76), Expect = 0.45 Identities = 21/68 (30%), Positives = 35/68 (51%) Frame = -1 Query: 423 ILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNN 244 +L E G ++ ++ ++ L+ AA G +CV LLL A V + +G TP+ A Sbjct: 715 LLNEEGLDINYSCEDGHSALYSAAKNGHTDCVRLLLNAEAQVNAADKNGFTPLCAAAAQG 774 Query: 243 QDEVLKLL 220 E ++LL Sbjct: 775 HFECVELL 782
>INVS_CHICK (Q8UVC3) Inversin| Length = 1106 Score = 63.9 bits (154), Expect = 4e-10 Identities = 42/120 (35%), Positives = 61/120 (50%), Gaps = 1/120 (0%) Frame = -1 Query: 570 SIVHHTASVGDGEGLKKALDGGAD-KDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVD 394 S VH A GD L K + G ++ KD+ED GR L + CAE LL+AGA V+ Sbjct: 16 SEVHAAAVNGDKSTLLKLIAGNSELKDKEDQFGRTPLMYCVLADRVDCAEALLKAGADVN 75 Query: 393 AMDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLLEK 214 D+++ T LH AA G + LLL ++++G TP+ + + + L LL K Sbjct: 76 RADRSRRTALHLAAQKGNYRFMKLLLARRGNWMQKDLEGMTPLHLTTRHKSPKCLALLLK 135 Score = 62.4 bits (150), Expect = 1e-09 Identities = 41/113 (36%), Positives = 55/113 (48%), Gaps = 2/113 (1%) Frame = -1 Query: 552 ASVGDGEGLKKALDGGADKDEE--DSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKN 379 A G ++ LD D D D ALH A G ++LLE A VDA+D Sbjct: 330 AGKGSDNVIRTMLDLKLDIDINMTDKYAGTALHAAALSGHVSTVKLLLERNAQVDALDVM 389 Query: 378 KNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 K+TPL A G KE + L+K GA V L + DG +P+ A L +V ++L Sbjct: 390 KHTPLFRACEMGHKEVIQTLIKGGARVDLVDQDGHSPLHWAALGGNADVCQIL 442 Score = 62.0 bits (149), Expect = 2e-09 Identities = 38/111 (34%), Positives = 59/111 (53%), Gaps = 2/111 (1%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLE--AGAAVDA 391 +H A G+ +K L + ++D EG LH + KC +LL+ A VD Sbjct: 85 LHLAAQKGNYRFMKLLLARRGNWMQKDLEGMTPLHLTTRHKSPKCLALLLKHMAPGEVDT 144 Query: 390 MDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQD 238 D+NK T LH++A Y E V LL+KH + + + +++GK P+ A NN+D Sbjct: 145 QDRNKQTALHWSAYYNNPEHVKLLIKHDSNIGIPDIEGKIPLHWA-ANNKD 194 Score = 51.6 bits (122), Expect = 2e-06 Identities = 30/103 (29%), Positives = 52/103 (50%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMD 385 +H A G +K L+ A D D L AC G + + L++ GA VD +D Sbjct: 361 LHAAALSGHVSTVKLLLERNAQVDALDVMKHTPLFRACEMGHKEVIQTLIKGGARVDLVD 420 Query: 384 KNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVA 256 ++ ++PLH+AA G + +L+++ +Q+ G+TP+ A Sbjct: 421 QDGHSPLHWAALGGNADVCQILIENKINPNVQDYAGRTPLQCA 463 Score = 50.4 bits (119), Expect = 5e-06 Identities = 33/109 (30%), Positives = 53/109 (48%) Frame = -1 Query: 546 VGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTP 367 +G E ++ + GGA D D +G LH+A G +IL+E + D TP Sbjct: 400 MGHKEVIQTLIKGGARVDLVDQDGHSPLHWAALGGNADVCQILIENKINPNVQDYAGRTP 459 Query: 366 LHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 L AA G C+ +LL++ A +Q+ +G+T + N + +KLL Sbjct: 460 LQCAAYGGYINCMVVLLENNADPNIQDKEGRTALHWLCNNGYLDAIKLL 508 Score = 48.1 bits (113), Expect = 2e-05 Identities = 36/130 (27%), Positives = 61/130 (46%), Gaps = 2/130 (1%) Frame = -1 Query: 570 SIVHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDA 391 S +H A G+ + + ++ + + +D GR L A G C +LLE A + Sbjct: 425 SPLHWAALGGNADVCQILIENKINPNVQDYAGRTPLQCAAYGGYINCMVVLLENNADPNI 484 Query: 390 MDKNKNTPLHYAAGYGRKECVDLLLKHGAAVT-LQNMDGK-TPIDVAKLNNQDEVLKLLE 217 DK T LH+ G + + LLL A ++N + + TP+D A L EV++ + Sbjct: 485 QDKEGRTALHWLCNNGYLDAIKLLLGFDAFPNHMENSEERYTPLDYALLGEHHEVIQFML 544 Query: 216 KDVFL*IASL 187 + L IA++ Sbjct: 545 EHGALSIAAI 554 Score = 48.1 bits (113), Expect = 2e-05 Identities = 32/94 (34%), Positives = 46/94 (48%), Gaps = 2/94 (2%) Frame = -1 Query: 489 EDSEGRRALHFACGYGEFKCAEILLE-AGAAVDAMDKNKNTPLHYAAGYGRKECVDLLLK 313 +D EGR LHFA G ++L G V + D TPLH+AA G + V LLL+ Sbjct: 217 QDYEGRTPLHFAVADGNVAVVDVLTSYEGCNVTSYDNLFRTPLHWAALLGHAQIVHLLLE 276 Query: 312 HGAAVTL-QNMDGKTPIDVAKLNNQDEVLKLLEK 214 T+ + G TP+ A +N E +++ K Sbjct: 277 RNKFGTIPSDSQGATPLHYAAQSNFAETVEVFLK 310 Score = 45.4 bits (106), Expect = 1e-04 Identities = 36/119 (30%), Positives = 53/119 (44%), Gaps = 2/119 (1%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDA-- 391 +H+ A E ++ L + KD+ D EGR + +A G G +L+ +D Sbjct: 293 LHYAAQSNFAETVEVFLKHPSVKDDSDLEGRTSFMWAAGKGSDNVIRTMLDLKLDIDINM 352 Query: 390 MDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLLEK 214 DK T LH AA G V LLL+ A V ++ TP+ A EV++ L K Sbjct: 353 TDKYAGTALHAAALSGHVSTVKLLLERNAQVDALDVMKHTPLFRACEMGHKEVIQTLIK 411 Score = 41.6 bits (96), Expect = 0.002 Identities = 28/97 (28%), Positives = 43/97 (44%), Gaps = 1/97 (1%) Frame = -1 Query: 507 GADKDEEDSEGRRALHFACGYGEFKCAEILLEAGA-AVDAMDKNKNTPLHYAAGYGRKEC 331 G + D+ R LH+A G + +LLE D TPLHYAA E Sbjct: 245 GCNVTSYDNLFRTPLHWAALLGHAQIVHLLLERNKFGTIPSDSQGATPLHYAAQSNFAET 304 Query: 330 VDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 V++ LKH + +++G+T A D V++ + Sbjct: 305 VEVFLKHPSVKDDSDLEGRTSFMWAAGKGSDNVIRTM 341 Score = 36.6 bits (83), Expect = 0.070 Identities = 32/122 (26%), Positives = 56/122 (45%), Gaps = 7/122 (5%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGE---FKCAEILLEAG---A 403 +H +A + E +K + ++ D EG+ LH+A + + +LEA + Sbjct: 153 LHWSAYYNNPEHVKLLIKHDSNIGIPDIEGKIPLHWAANNKDPSAIHTVKCILEAAPTES 212 Query: 402 AVDAMDKNKNTPLHYAAGYGRKECVDLLLKH-GAAVTLQNMDGKTPIDVAKLNNQDEVLK 226 ++ D TPLH+A G VD+L + G VT + +TP+ A L +++ Sbjct: 213 LLNWQDYEGRTPLHFAVADGNVAVVDVLTSYEGCNVTSYDNLFRTPLHWAALLGHAQIVH 272 Query: 225 LL 220 LL Sbjct: 273 LL 274 Score = 32.0 bits (71), Expect = 1.7 Identities = 23/91 (25%), Positives = 38/91 (41%), Gaps = 2/91 (2%) Frame = -1 Query: 486 DSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLL--LK 313 DS+G LH+A + E+ L+ + D D T +AAG G + + LK Sbjct: 286 DSQGATPLHYAAQSNFAETVEVFLKHPSVKDDSDLEGRTSFMWAAGKGSDNVIRTMLDLK 345 Query: 312 HGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 + + + T + A L+ +KLL Sbjct: 346 LDIDINMTDKYAGTALHAAALSGHVSTVKLL 376
>Y1861_PYRAE (Q8ZWC4) Hypothetical ANK-repeat protein PAE1861| Length = 256 Score = 63.5 bits (153), Expect = 5e-10 Identities = 37/106 (34%), Positives = 58/106 (54%) Frame = -1 Query: 570 SIVHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDA 391 S++H A GD +K L+ G D + D+ G+ LH A + +C E+LL+ G V+ Sbjct: 127 SLLHLVA--GDAGLVKLLLEYGVDPNARDAHGKTPLHMASEHNCAQCVELLLKRGPDVNV 184 Query: 390 MDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAK 253 D TPLHYA +C+ LLL++GA + + G+TP+ A+ Sbjct: 185 KDGAGRTPLHYADDV---DCIKLLLRYGADLNAVDNMGRTPLHYAE 227 Score = 51.2 bits (121), Expect = 3e-06 Identities = 28/76 (36%), Positives = 42/76 (55%) Frame = -1 Query: 483 SEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLLKHGA 304 S G LH G + ++LLE G +A D + TPLH A+ + +CV+LLLK G Sbjct: 123 SHGESLLHLVAG--DAGLVKLLLEYGVDPNARDAHGKTPLHMASEHNCAQCVELLLKRGP 180 Query: 303 AVTLQNMDGKTPIDVA 256 V +++ G+TP+ A Sbjct: 181 DVNVKDGAGRTPLHYA 196 Score = 50.8 bits (120), Expect = 4e-06 Identities = 30/75 (40%), Positives = 41/75 (54%) Frame = -1 Query: 444 GEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPI 265 GE + LL G + D D TPL+YAA G VDLL+K GA ++ +GKTPI Sbjct: 13 GEAELLTRLLNEGCSPDVQDDYGRTPLYYAAERGDVGTVDLLIKAGADPNARDREGKTPI 72 Query: 264 DVAKLNNQDEVLKLL 220 +A + + V+ LL Sbjct: 73 IIATQSRKFGVIPLL 87 Score = 42.7 bits (99), Expect = 0.001 Identities = 21/65 (32%), Positives = 36/65 (55%) Frame = -1 Query: 558 HTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKN 379 + A G+ E L + L+ G D +D GR L++A G+ ++L++AGA +A D+ Sbjct: 8 NAARRGEAELLTRLLNEGCSPDVQDDYGRTPLYYAAERGDVGTVDLLIKAGADPNARDRE 67 Query: 378 KNTPL 364 TP+ Sbjct: 68 GKTPI 72
>ANR50_HUMAN (Q9ULJ7) Ankyrin repeat domain-containing protein 50| Length = 1375 Score = 63.5 bits (153), Expect = 5e-10 Identities = 34/99 (34%), Positives = 54/99 (54%) Frame = -1 Query: 516 LDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRK 337 L+ GA+ + D+EGR ALH +C G + ++L+ A V+A D K + L AA G Sbjct: 912 LENGANVEASDAEGRTALHVSCWQGHMEMVQVLIAYHADVNAADNEKRSALQSAAWQGHV 971 Query: 336 ECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 + V LL++HGA V G T + +A +V+++L Sbjct: 972 KVVQLLIEHGAVVDHTCNQGATALCIAAQEGHIDVVQVL 1010 Score = 63.5 bits (153), Expect = 5e-10 Identities = 40/111 (36%), Positives = 54/111 (48%) Frame = -1 Query: 552 ASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKN 373 AS G + +D GA+ D D +G L A G ++LLE GA VD D N Sbjct: 669 ASKGHASVVSLLIDRGAEVDHCDKDGMTPLLVAAYEGHVDVVDLLLEGGADVDHTDNNGR 728 Query: 372 TPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 TPL AA G V+ LL GAAV + +G+T + +A EV++ L Sbjct: 729 TPLLAAASMGHASVVNTLLFWGAAVDSIDSEGRTVLSIASAQGNVEVVRTL 779 Score = 60.8 bits (146), Expect = 3e-09 Identities = 37/97 (38%), Positives = 51/97 (52%) Frame = -1 Query: 504 ADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVD 325 AD + D+E R AL A G K ++L+E GA VD T L AA G + V Sbjct: 949 ADVNAADNEKRSALQSAAWQGHVKVVQLLIEHGAVVDHTCNQGATALCIAAQEGHIDVVQ 1008 Query: 324 LLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLLEK 214 +LL+HGA + G+T + VA N +++KLLEK Sbjct: 1009 VLLEHGADPNHADQFGRTAMRVAAKNGHSQIIKLLEK 1045 Score = 60.8 bits (146), Expect = 3e-09 Identities = 42/116 (36%), Positives = 59/116 (50%), Gaps = 5/116 (4%) Frame = -1 Query: 552 ASVGDGEGLKKALDGGADKDEEDSEGRRALHFAC-----GYGEFKCAEILLEAGAAVDAM 388 A +G E ++ LD GA+ + ED +GR AL A G +L++ GA VD Sbjct: 631 AYMGHREIVEHLLDHGAEVNHEDVDGRTALSVAALCVPASKGHASVVSLLIDRGAEVDHC 690 Query: 387 DKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 DK+ TPL AA G + VDLLL+ GA V + +G+TP+ A V+ L Sbjct: 691 DKDGMTPLLVAAYEGHVDVVDLLLEGGADVDHTDNNGRTPLLAAASMGHASVVNTL 746 Score = 59.7 bits (143), Expect = 8e-09 Identities = 32/117 (27%), Positives = 60/117 (51%) Frame = -1 Query: 570 SIVHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDA 391 +++ ++ G+ E ++ LD G D++ D G LH A G E L+E GA + Sbjct: 762 TVLSIASAQGNVEVVRTLLDRGLDENHRDDAGWTPLHMAAFEGHRLICEALIEQGARTNE 821 Query: 390 MDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 +D + P A+ G +CV +LL++ + + + DG+ + VA L ++++LL Sbjct: 822 IDNDGRIPFILASQEGHYDCVQILLENKSNIDQRGYDGRNALRVAALEGHRDIVELL 878 Score = 55.8 bits (133), Expect = 1e-07 Identities = 33/108 (30%), Positives = 53/108 (49%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMD 385 +H A G + ++ GA +E D++GR A G + C +ILLE + +D Sbjct: 797 LHMAAFEGHRLICEALIEQGARTNEIDNDGRIPFILASQEGHYDCVQILLENKSNIDQRG 856 Query: 384 KNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQ 241 + L AA G ++ V+LL HGA V ++ DG+ + + L NQ Sbjct: 857 YDGRNALRVAALEGHRDIVELLFSHGADVNCKDADGRPTLYILALENQ 904 Score = 53.9 bits (128), Expect = 4e-07 Identities = 36/98 (36%), Positives = 48/98 (48%) Frame = -1 Query: 543 GDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPL 364 G E + L G D D++ R AL A G LL+ GA V+ D T L Sbjct: 568 GHTEVVSALLYAGVKVDCADADSRTALRAAAWGGHEDIVLNLLQHGAEVNKADNEGRTAL 627 Query: 363 HYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKL 250 AA G +E V+ LL HGA V +++DG+T + VA L Sbjct: 628 IAAAYMGHREIVEHLLDHGAEVNHEDVDGRTALSVAAL 665 Score = 52.4 bits (124), Expect = 1e-06 Identities = 33/87 (37%), Positives = 42/87 (48%) Frame = -1 Query: 516 LDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRK 337 L+GGAD D D+ GR L A G LL GAAVD++D T L A+ G Sbjct: 714 LEGGADVDHTDNNGRTPLLAAASMGHASVVNTLLFWGAAVDSIDSEGRTVLSIASAQGNV 773 Query: 336 ECVDLLLKHGAAVTLQNMDGKTPIDVA 256 E V LL G ++ G TP+ +A Sbjct: 774 EVVRTLLDRGLDENHRDDAGWTPLHMA 800 Score = 51.6 bits (122), Expect = 2e-06 Identities = 34/111 (30%), Positives = 50/111 (45%) Frame = -1 Query: 552 ASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKN 373 AS+G + L GA D DSEGR L A G + LL+ G + D Sbjct: 735 ASMGHASVVNTLLFWGAAVDSIDSEGRTVLSIASAQGNVEVVRTLLDRGLDENHRDDAGW 794 Query: 372 TPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 TPLH AA G + + L++ GA + DG+ P +A + +++L Sbjct: 795 TPLHMAAFEGHRLICEALIEQGARTNEIDNDGRIPFILASQEGHYDCVQIL 845 Score = 51.2 bits (121), Expect = 3e-06 Identities = 32/105 (30%), Positives = 50/105 (47%) Frame = -1 Query: 534 EGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYA 355 + ++ LD GA ++ DS GR L A G +L+ GA ++ D + +TPL A Sbjct: 472 DSIRTLLDNGASVNQCDSNGRTLLANAAYSGSLDVVNLLVSRGADLEIEDAHGHTPLTLA 531 Query: 354 AGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 A G + V+ L+ GA + + DG T + A EV+ L Sbjct: 532 ARQGHTKVVNCLIGCGANINHTDQDGWTALRSAAWGGHTEVVSAL 576 Score = 50.1 bits (118), Expect = 6e-06 Identities = 32/96 (33%), Positives = 47/96 (48%) Frame = -1 Query: 507 GADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECV 328 GA+ + D +G AL A G + LL AG VD D + T L AA G ++ V Sbjct: 547 GANINHTDQDGWTALRSAAWGGHTEVVSALLYAGVKVDCADADSRTALRAAAWGGHEDIV 606 Query: 327 DLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 LL+HGA V + +G+T + A E+++ L Sbjct: 607 LNLLQHGAEVNKADNEGRTALIAAAYMGHREIVEHL 642 Score = 48.5 bits (114), Expect = 2e-05 Identities = 29/96 (30%), Positives = 48/96 (50%) Frame = -1 Query: 507 GADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECV 328 GAD + +D++GR L+ + AE LE GA V+A D T LH + G E V Sbjct: 882 GADVNCKDADGRPTLYILALENQLTMAEYFLENGANVEASDAEGRTALHVSCWQGHMEMV 941 Query: 327 DLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 +L+ + A V + + ++ + A +V++LL Sbjct: 942 QVLIAYHADVNAADNEKRSALQSAAWQGHVKVVQLL 977 Score = 47.4 bits (111), Expect = 4e-05 Identities = 35/119 (29%), Positives = 55/119 (46%), Gaps = 1/119 (0%) Frame = -1 Query: 570 SIVHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDA 391 +++ + A G + + + GAD + ED+ G L A G K L+ GA ++ Sbjct: 493 TLLANAAYSGSLDVVNLLVSRGADLEIEDAHGHTPLTLAARQGHTKVVNCLIGCGANINH 552 Query: 390 MDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKL-NNQDEVLKLLE 217 D++ T L AA G E V LL G V + D +T + A ++D VL LL+ Sbjct: 553 TDQDGWTALRSAAWGGHTEVVSALLYAGVKVDCADADSRTALRAAAWGGHEDIVLNLLQ 611 Score = 39.3 bits (90), Expect = 0.011 Identities = 29/104 (27%), Positives = 50/104 (48%) Frame = -1 Query: 570 SIVHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDA 391 S + A G + ++ ++ GA D ++G AL A G ++LLE GA + Sbjct: 960 SALQSAAWQGHVKVVQLLIEHGAVVDHTCNQGATALCIAAQEGHIDVVQVLLEHGADPNH 1019 Query: 390 MDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDV 259 D+ T + AA G + + LL K+GA+ +++G +P V Sbjct: 1020 ADQFGRTAMRVAAKNGHSQIIKLLEKYGAS----SLNGCSPSPV 1059
>ACBD6_RAT (Q5RJK8) Acyl-CoA-binding domain-containing protein 6| Length = 282 Score = 63.5 bits (153), Expect = 5e-10 Identities = 35/93 (37%), Positives = 50/93 (53%) Frame = -1 Query: 501 DKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDL 322 D + D EGR LH+AC G + ++LL+ A ++ D T LHYAA + V+L Sbjct: 184 DVNMTDEEGRALLHWACDRGHKELVKVLLQCEAGINCQDNEGQTALHYAAACEFSDIVEL 243 Query: 321 LLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKL 223 LL+ GA TL++ DG P +V VL+L Sbjct: 244 LLQSGADPTLRDQDGCLPEEVTGCKAVSLVLQL 276 Score = 34.3 bits (77), Expect = 0.35 Identities = 18/60 (30%), Positives = 32/60 (53%) Frame = -1 Query: 399 VDAMDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 V+ D+ LH+A G KE V +LL+ A + Q+ +G+T + A ++++LL Sbjct: 185 VNMTDEEGRALLHWACDRGHKELVKVLLQCEAGINCQDNEGQTALHYAAACEFSDIVELL 244 Score = 32.3 bits (72), Expect = 1.3 Identities = 20/68 (29%), Positives = 34/68 (50%) Frame = -1 Query: 570 SIVHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDA 391 +++H G E +K L A + +D+EG+ ALH+A E+LL++GA Sbjct: 194 ALLHWACDRGHKELVKVLLQCEAGINCQDNEGQTALHYAAACEFSDIVELLLQSGADPTL 253 Query: 390 MDKNKNTP 367 D++ P Sbjct: 254 RDQDGCLP 261
>CTTB2_HORSE (Q2QLA2) Cortactin-binding protein 2 (CortBP2)| Length = 1665 Score = 63.5 bits (153), Expect = 5e-10 Identities = 38/96 (39%), Positives = 50/96 (52%) Frame = -1 Query: 507 GADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECV 328 G D + +G AL+ A G C +LL A A VDA DKN TPL AA G +CV Sbjct: 735 GLDINYSCEDGHSALYSAAKNGHTDCVRLLLNAEAQVDAADKNGFTPLCAAAAQGHFKCV 794 Query: 327 DLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 LL+ + A + G+TP+ +A N E +KLL Sbjct: 795 QLLIAYDANINHAADGGQTPLYLACKNGNKECIKLL 830 Score = 62.8 bits (151), Expect = 9e-10 Identities = 37/117 (31%), Positives = 57/117 (48%) Frame = -1 Query: 570 SIVHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDA 391 S ++ A G + ++ L+ A D D G L A G FKC ++L+ A ++ Sbjct: 747 SALYSAAKNGHTDCVRLLLNAEAQVDAADKNGFTPLCAAAAQGHFKCVQLLIAYDANINH 806 Query: 390 MDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 TPL+ A G KEC+ LLL+ G+ +++ DG TP+ A + LKLL Sbjct: 807 AADGGQTPLYLACKNGNKECIKLLLEAGSDRSIKTRDGWTPVHAAVDTGNVDSLKLL 863 Score = 39.7 bits (91), Expect = 0.008 Identities = 20/58 (34%), Positives = 32/58 (55%) Frame = -1 Query: 477 GRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLLKHGA 304 G+ L+ AC G +C ++LLEAG+ ++ TP+H A G + + LL+ H A Sbjct: 811 GQTPLYLACKNGNKECIKLLLEAGSDRSIKTRDGWTPVHAAVDTGNVDSLKLLMYHRA 868 Score = 32.0 bits (71), Expect = 1.7 Identities = 20/68 (29%), Positives = 35/68 (51%) Frame = -1 Query: 423 ILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNN 244 +L E G ++ ++ ++ L+ AA G +CV LLL A V + +G TP+ A Sbjct: 730 LLNEEGLDINYSCEDGHSALYSAAKNGHTDCVRLLLNAEAQVDAADKNGFTPLCAAAAQG 789 Query: 243 QDEVLKLL 220 + ++LL Sbjct: 790 HFKCVQLL 797
>ASB13_MOUSE (Q8VBX0) Ankyrin repeat and SOCS box protein 13 (ASB-13)| Length = 278 Score = 63.5 bits (153), Expect = 5e-10 Identities = 40/115 (34%), Positives = 62/115 (53%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMD 385 VH A G+ L++ +D GA ++ + LH A G+ +C ++LL AGA VDA + Sbjct: 23 VHEAAQRGESLQLQQLIDSGACVNQVTVDSITPLHAASLQGQAQCVQLLLAAGAQVDARN 82 Query: 384 KNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 + +TPL A G ECV LLL +GA V + +P+ A ++ E ++LL Sbjct: 83 IDGSTPLCDACASGSIECVKLLLSYGAKVN-PPLYTASPLHEACMSGSSECVRLL 136 Score = 57.4 bits (137), Expect = 4e-08 Identities = 33/85 (38%), Positives = 49/85 (57%) Frame = -1 Query: 474 RRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLLKHGAAVT 295 R +H A GE + L+++GA V+ + + TPLH A+ G+ +CV LLL GA V Sbjct: 20 RTPVHEAAQRGESLQLQQLIDSGACVNQVTVDSITPLHAASLQGQAQCVQLLLAAGAQVD 79 Query: 294 LQNMDGKTPIDVAKLNNQDEVLKLL 220 +N+DG TP+ A + E +KLL Sbjct: 80 ARNIDGSTPLCDACASGSIECVKLL 104 Score = 55.8 bits (133), Expect = 1e-07 Identities = 32/103 (31%), Positives = 51/103 (49%) Frame = -1 Query: 570 SIVHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDA 391 S +H G E ++ +D GA+ + D LH AC C ++LL AGA V+A Sbjct: 119 SPLHEACMSGSSECVRLLIDVGANLEAHDCHFGTPLHVACAREHLDCVKVLLNAGANVNA 178 Query: 390 MDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPID 262 K T LH+AA + +++L++ G + ++ GK P D Sbjct: 179 A-KLHETALHHAAKVKNVDLIEMLIEFGGNIYARDNRGKKPSD 220 Score = 52.8 bits (125), Expect = 9e-07 Identities = 29/83 (34%), Positives = 42/83 (50%) Frame = -1 Query: 465 LHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQN 286 LH AC G +C +L++ GA ++A D + TPLH A +CV +LL GA V Sbjct: 121 LHEACMSGSSECVRLLIDVGANLEAHDCHFGTPLHVACAREHLDCVKVLLNAGANVNAAK 180 Query: 285 MDGKTPIDVAKLNNQDEVLKLLE 217 + AK+ N D + L+E Sbjct: 181 LHETALHHAAKVKNVDLIEMLIE 203 Score = 52.8 bits (125), Expect = 9e-07 Identities = 37/114 (32%), Positives = 55/114 (48%), Gaps = 1/114 (0%) Frame = -1 Query: 558 HTASV-GDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDK 382 H AS+ G + ++ L GA D + +G L AC G +C ++LL GA V+ Sbjct: 57 HAASLQGQAQCVQLLLAAGAQVDARNIDGSTPLCDACASGSIECVKLLLSYGAKVNP-PL 115 Query: 381 NKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 +PLH A G ECV LL+ GA + + TP+ VA + +K+L Sbjct: 116 YTASPLHEACMSGSSECVRLLIDVGANLEAHDCHFGTPLHVACAREHLDCVKVL 169 Score = 33.9 bits (76), Expect = 0.45 Identities = 18/53 (33%), Positives = 27/53 (50%) Frame = -1 Query: 378 KNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 + TP+H AA G + L+ GA V +D TP+ A L Q + ++LL Sbjct: 19 ERTPVHEAAQRGESLQLQQLIDSGACVNQVTVDSITPLHAASLQGQAQCVQLL 71
>ASB3_MOUSE (Q9WV72) Ankyrin repeat and SOCS box protein 3 (ASB-3)| Length = 525 Score = 63.2 bits (152), Expect = 7e-10 Identities = 43/117 (36%), Positives = 59/117 (50%), Gaps = 2/117 (1%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMD 385 +H + G+ E +K L GAD++ +D G L A YG+ + IL+ +GA V+ Sbjct: 150 LHQASFQGNAETIKLLLKQGADRECQDDFGITPLFVAAQYGKLESMSILISSGANVNCQA 209 Query: 384 KNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQ-NMDG-KTPIDVAKLNNQDEVLKLL 220 +K TPL AA G +CV+LLL GA L N D + PI A E L LL Sbjct: 210 LDKATPLFIAAQEGHTKCVELLLSSGADPDLYCNEDNWQLPIHAAAQMGHTETLDLL 266 Score = 55.8 bits (133), Expect = 1e-07 Identities = 36/90 (40%), Positives = 46/90 (51%), Gaps = 1/90 (1%) Frame = -1 Query: 480 EGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLLKHGAA 301 EG ALH A G +K +ILLEAGA + + TPL A GR + + LLL+HGA Sbjct: 78 EGFCALHLAVSQGHWKITQILLEAGADPNETTLEETTPLFLAVESGRIDVLKLLLQHGAN 137 Query: 300 VT-LQNMDGKTPIDVAKLNNQDEVLKLLEK 214 V +M G + A E +KLL K Sbjct: 138 VNGSHSMSGWNSLHQASFQGNAETIKLLLK 167 Score = 52.8 bits (125), Expect = 9e-07 Identities = 35/104 (33%), Positives = 53/104 (50%), Gaps = 1/104 (0%) Frame = -1 Query: 528 LKKALDGGADKDEEDS-EGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAA 352 LK L GA+ + S G +LH A G + ++LL+ GA + D TPL AA Sbjct: 128 LKLLLQHGANVNGSHSMSGWNSLHQASFQGNAETIKLLLKQGADRECQDDFGITPLFVAA 187 Query: 351 GYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 YG+ E + +L+ GA V Q +D TP+ +A + ++LL Sbjct: 188 QYGKLESMSILISSGANVNCQALDKATPLFIAAQEGHTKCVELL 231 Score = 45.8 bits (107), Expect = 1e-04 Identities = 32/113 (28%), Positives = 50/113 (44%), Gaps = 2/113 (1%) Frame = -1 Query: 552 ASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAM--DKN 379 A G E + + GA+ + + + L A G KC E+LL +GA D + N Sbjct: 187 AQYGKLESMSILISSGANVNCQALDKATPLFIAAQEGHTKCVELLLSSGADPDLYCNEDN 246 Query: 378 KNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 P+H AA G E +DLL+ D +P+ A ++E L++L Sbjct: 247 WQLPIHAAAQMGHTETLDLLIPRTNRACDTEPDKVSPVYSAVFGGREECLEML 299 Score = 33.9 bits (76), Expect = 0.45 Identities = 23/84 (27%), Positives = 42/84 (50%), Gaps = 2/84 (2%) Frame = -1 Query: 552 ASVGDGEGLKKALDGGADKDEEDSEGRRAL--HFACGYGEFKCAEILLEAGAAVDAMDKN 379 A G + ++ L GAD D +E L H A G + ++L+ + + Sbjct: 220 AQEGHTKCVELLLSSGADPDLYCNEDNWQLPIHAAAQMGHTETLDLLIPRTNRACDTEPD 279 Query: 378 KNTPLHYAAGYGRKECVDLLLKHG 307 K +P++ A GR+EC+++LL++G Sbjct: 280 KVSPVYSAVFGGREECLEMLLQNG 303 Score = 32.0 bits (71), Expect = 1.7 Identities = 19/62 (30%), Positives = 28/62 (45%) Frame = -1 Query: 501 DKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDL 322 D E S+ + A G K LL+ G +VD D P+H AA + EC+ + Sbjct: 2 DFTEAYSDTCSTVGLAAREGNVKILRKLLKKGRSVDVADNRGWMPIHEAAYHNAVECLQM 61 Query: 321 LL 316 L+ Sbjct: 62 LI 63
>ACBD6_XENLA (Q4V869) Acyl-CoA-binding domain-containing protein 6| Length = 286 Score = 63.2 bits (152), Expect = 7e-10 Identities = 33/84 (39%), Positives = 45/84 (53%) Frame = -1 Query: 510 GGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKEC 331 G D + D EGR LH+AC G + ++L A ++ D TPLHYA+ + Sbjct: 172 GSVDVNVADDEGRSLLHWACDRGHTQLVSVILFHNAHINMQDSEGQTPLHYASACEFPDI 231 Query: 330 VDLLLKHGAAVTLQNMDGKTPIDV 259 VDLLL HGA +L + DG P +V Sbjct: 232 VDLLLDHGADPSLVDNDGFQPHEV 255 Score = 37.0 bits (84), Expect = 0.053 Identities = 17/60 (28%), Positives = 32/60 (53%) Frame = -1 Query: 399 VDAMDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 V+ D + LH+A G + V ++L H A + +Q+ +G+TP+ A +++ LL Sbjct: 176 VNVADDEGRSLLHWACDRGHTQLVSVILFHNAHINMQDSEGQTPLHYASACEFPDIVDLL 235
>TNI3K_HUMAN (Q59H18) Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1)| (TNNI3-interacting kinase) (Cardiac ankyrin repeat kinase) Length = 936 Score = 63.2 bits (152), Expect = 7e-10 Identities = 40/118 (33%), Positives = 57/118 (48%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMD 385 +H + E + L GAD + G ALH A G + A++LL+ GA V+ D Sbjct: 206 LHLAVYKDNAELITSLLHSGADIQQVGYGGLTALHIATIAGHLEAADVLLQHGANVNIQD 265 Query: 384 KNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLLEKD 211 TPLH AA YG ++ LLLK GA V + G P+ +A + KLL ++ Sbjct: 266 AVFFTPLHIAAYYGHEQVTRLLLKFGADVNVSGEVGDRPLHLASAKGFLNIAKLLMEE 323 Score = 47.8 bits (112), Expect = 3e-05 Identities = 30/88 (34%), Positives = 43/88 (48%) Frame = -1 Query: 477 GRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLLKHGAAV 298 G ALH A + LL +GA + + T LH A G E D+LL+HGA V Sbjct: 202 GFTALHLAVYKDNAELITSLLHSGADIQQVGYGGLTALHIATIAGHLEAADVLLQHGANV 261 Query: 297 TLQNMDGKTPIDVAKLNNQDEVLKLLEK 214 +Q+ TP+ +A ++V +LL K Sbjct: 262 NIQDAVFFTPLHIAAYYGHEQVTRLLLK 289 Score = 44.7 bits (104), Expect = 3e-04 Identities = 34/122 (27%), Positives = 56/122 (45%), Gaps = 3/122 (2%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMD 385 +H G E L GA+ + +D+ LH A YG + +LL+ GA V+ Sbjct: 239 LHIATIAGHLEAADVLLQHGANVNIQDAVFFTPLHIAAYYGHEQVTRLLLKFGADVNVSG 298 Query: 384 KNKNTPLHYAAGYGRKECVDLLLKHG--AAVTLQNMDGKTPID-VAKLNNQDEVLKLLEK 214 + + PLH A+ G LL++ G A V Q+ + P+ ++ + D V LL+ Sbjct: 299 EVGDRPLHLASAKGFLNIAKLLMEEGSKADVNAQDNEDHVPLHFCSRFGHHDIVKYLLQS 358 Query: 213 DV 208 D+ Sbjct: 359 DL 360 Score = 30.4 bits (67), Expect = 5.0 Identities = 22/82 (26%), Positives = 39/82 (47%), Gaps = 4/82 (4%) Frame = -1 Query: 504 ADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKN--KNTPLHYAAGYGRKEC 331 AD + +D+E LHF +G + LL++ V N +TPLH A G+ E Sbjct: 327 ADVNAQDNEDHVPLHFCSRFGHHDIVKYLLQSDLEVQPHVVNIYGDTPLHLACYNGKFEV 386 Query: 330 VDLLLKHGA--AVTLQNMDGKT 271 +++ ++T +N+ +T Sbjct: 387 AKEIIQISGTESLTKENIFSET 408
>MIB1_XENLA (Q6GNY1) Ubiquitin ligase protein MIB1 (EC 6.3.2.-) (Mind bomb| homolog 1) Length = 1011 Score = 63.2 bits (152), Expect = 7e-10 Identities = 36/103 (34%), Positives = 53/103 (51%) Frame = -1 Query: 528 LKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAG 349 LK L D + ED +G RA+H A E E+L GA ++A +K + TPLH A Sbjct: 480 LKLLLKHSVDVEAEDKDGDRAVHHAAFGDEGTVIEVLQRGGADLNARNKRRQTPLHIAVN 539 Query: 348 YGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 G + V LL +LQ+ +G TP+ A +D++L +L Sbjct: 540 KGHLQVVKKLLDFSCHPSLQDSEGDTPLHDAISKKRDDILAVL 582 Score = 55.1 bits (131), Expect = 2e-07 Identities = 33/115 (28%), Positives = 53/115 (46%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMD 385 VHH A +G ++ GGAD + + + LH A G + + LL+ D Sbjct: 501 VHHAAFGDEGTVIEVLQRGGADLNARNKRRQTPLHIAVNKGHLQVVKKLLDFSCHPSLQD 560 Query: 384 KNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 +TPLH A R + + +LL+ GA VT+ N +G + A L +++L Sbjct: 561 SEGDTPLHDAISKKRDDILAVLLEAGADVTITNNNGFNALHHAALRGNPSAMRVL 615 Score = 52.0 bits (123), Expect = 2e-06 Identities = 40/118 (33%), Positives = 54/118 (45%), Gaps = 3/118 (2%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMD 385 +H + G + +KK LD +DSEG LH A +LLEAGA V + Sbjct: 534 LHIAVNKGHLQVVKKLLDFSCHPSLQDSEGDTPLHDAISKKRDDILAVLLEAGADVTITN 593 Query: 384 KNKNTPLHYAAGYGRKECVDLLLK---HGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 N LH+AA G + +LL V + DG T + +A LNN EV +LL Sbjct: 594 NNGFNALHHAALRGNPSAMRVLLSKLPRPWIVDEKKDDGYTALHLAALNNHVEVAELL 651 Score = 49.3 bits (116), Expect = 1e-05 Identities = 35/120 (29%), Positives = 59/120 (49%), Gaps = 4/120 (3%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADK---DEEDSEGRRALHFACGYGEFKCAEILLEAGAA-V 397 +HH A G+ ++ L DE+ +G ALH A + AE+L+ G+A + Sbjct: 600 LHHAALRGNPSAMRVLLSKLPRPWIVDEKKDDGYTALHLAALNNHVEVAELLVHQGSANL 659 Query: 396 DAMDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLLE 217 D + N+ T LH A + V LL++ A + +Q+ DG TP+ A ++ L+ L+ Sbjct: 660 DIQNVNQQTALHLAVERQHTQIVRLLVRAEAKLDIQDKDGDTPLHEALRHHTLSQLRQLQ 719 Score = 38.1 bits (87), Expect = 0.024 Identities = 23/86 (26%), Positives = 43/86 (50%) Frame = -1 Query: 477 GRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLLKHGAAV 298 G A+ A G ++LL+ V+A DK+ + +H+AA +++L + GA + Sbjct: 464 GHTAMQAASQNGHVDILKLLLKHSVDVEAEDKDGDRAVHHAAFGDEGTVIEVLQRGGADL 523 Query: 297 TLQNMDGKTPIDVAKLNNQDEVLKLL 220 +N +TP+ +A +V+K L Sbjct: 524 NARNKRRQTPLHIAVNKGHLQVVKKL 549 Score = 30.0 bits (66), Expect = 6.5 Identities = 14/54 (25%), Positives = 29/54 (53%) Frame = -1 Query: 375 NTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLLEK 214 +T + A+ G + + LLLKH V ++ DG + A ++ V+++L++ Sbjct: 465 HTAMQAASQNGHVDILKLLLKHSVDVEAEDKDGDRAVHHAAFGDEGTVIEVLQR 518
>MIB1_MOUSE (Q80SY4) Ubiquitin ligase protein MIB1 (EC 6.3.2.-) (Mind bomb| homolog 1) (DAPK-interacting protein 1) (DIP-1) Length = 1006 Score = 63.2 bits (152), Expect = 7e-10 Identities = 36/103 (34%), Positives = 53/103 (51%) Frame = -1 Query: 528 LKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAG 349 LK L D + ED +G RA+H A E E+L A ++A +K + TPLH A Sbjct: 480 LKLLLKQNVDVEAEDKDGDRAVHHAAFGDEGAVIEVLHRGSADLNARNKRRQTPLHIAVN 539 Query: 348 YGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 G + V LL G +LQ+ +G TP+ A +D++L +L Sbjct: 540 KGHLQVVKTLLDFGCHPSLQDSEGDTPLHDAISKKRDDILAVL 582 Score = 55.5 bits (132), Expect = 1e-07 Identities = 33/115 (28%), Positives = 53/115 (46%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMD 385 VHH A +G ++ G AD + + + LH A G + + LL+ G D Sbjct: 501 VHHAAFGDEGAVIEVLHRGSADLNARNKRRQTPLHIAVNKGHLQVVKTLLDFGCHPSLQD 560 Query: 384 KNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 +TPLH A R + + +LL+ GA VT+ N +G + A L +++L Sbjct: 561 SEGDTPLHDAISKKRDDILAVLLEAGADVTITNNNGFNALHHAALRGNPSAMRVL 615 Score = 52.0 bits (123), Expect = 2e-06 Identities = 40/118 (33%), Positives = 54/118 (45%), Gaps = 3/118 (2%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMD 385 +H + G + +K LD G +DSEG LH A +LLEAGA V + Sbjct: 534 LHIAVNKGHLQVVKTLLDFGCHPSLQDSEGDTPLHDAISKKRDDILAVLLEAGADVTITN 593 Query: 384 KNKNTPLHYAAGYGRKECVDLLLK---HGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 N LH+AA G + +LL V + DG T + +A LNN EV +LL Sbjct: 594 NNGFNALHHAALRGNPSAMRVLLSKLPRPWIVDEKKDDGYTALHLAALNNHVEVAELL 651 Score = 51.6 bits (122), Expect = 2e-06 Identities = 39/140 (27%), Positives = 65/140 (46%), Gaps = 4/140 (2%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADK---DEEDSEGRRALHFACGYGEFKCAEILLEAG-AAV 397 +HH A G+ ++ L DE+ +G ALH A + AE+L+ G A + Sbjct: 600 LHHAALRGNPSAMRVLLSKLPRPWIVDEKKDDGYTALHLAALNNHVEVAELLVHQGNANL 659 Query: 396 DAMDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLLE 217 D + N+ T LH A + V LL++ GA + +Q+ DG TP+ A ++ L+ L+ Sbjct: 660 DIQNVNQQTALHLAVERQHTQIVRLLVRAGAKLDIQDKDGDTPLHEALRHHTLSQLRQLQ 719 Query: 216 KDVFL*IASLGSHEETWPSS 157 + +G + W S Sbjct: 720 D-----MQDVGKVDAAWEPS 734 Score = 36.2 bits (82), Expect = 0.091 Identities = 22/86 (25%), Positives = 42/86 (48%) Frame = -1 Query: 477 GRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLLKHGAAV 298 G A+ A G ++LL+ V+A DK+ + +H+AA +++L + A + Sbjct: 464 GHTAMQAASQNGHVDILKLLLKQNVDVEAEDKDGDRAVHHAAFGDEGAVIEVLHRGSADL 523 Query: 297 TLQNMDGKTPIDVAKLNNQDEVLKLL 220 +N +TP+ +A +V+K L Sbjct: 524 NARNKRRQTPLHIAVNKGHLQVVKTL 549
>MIB1_HUMAN (Q86YT6) Ubiquitin ligase protein MIB1 (EC 6.3.2.-) (Mind bomb| homolog 1) (DAPK-interacting protein 1) (DIP-1) (Zinc finger ZZ type with ankyrin repeat domain protein 2) Length = 1006 Score = 63.2 bits (152), Expect = 7e-10 Identities = 36/103 (34%), Positives = 53/103 (51%) Frame = -1 Query: 528 LKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAG 349 LK L D + ED +G RA+H A E E+L A ++A +K + TPLH A Sbjct: 480 LKLLLKQNVDVEAEDKDGDRAVHHAAFGDEGAVIEVLHRGSADLNARNKRRQTPLHIAVN 539 Query: 348 YGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 G + V LL G +LQ+ +G TP+ A +D++L +L Sbjct: 540 KGHLQVVKTLLDFGCHPSLQDSEGDTPLHDAISKKRDDILAVL 582 Score = 55.5 bits (132), Expect = 1e-07 Identities = 33/115 (28%), Positives = 53/115 (46%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMD 385 VHH A +G ++ G AD + + + LH A G + + LL+ G D Sbjct: 501 VHHAAFGDEGAVIEVLHRGSADLNARNKRRQTPLHIAVNKGHLQVVKTLLDFGCHPSLQD 560 Query: 384 KNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 +TPLH A R + + +LL+ GA VT+ N +G + A L +++L Sbjct: 561 SEGDTPLHDAISKKRDDILAVLLEAGADVTITNNNGFNALHHAALRGNPSAMRVL 615 Score = 52.0 bits (123), Expect = 2e-06 Identities = 40/118 (33%), Positives = 54/118 (45%), Gaps = 3/118 (2%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMD 385 +H + G + +K LD G +DSEG LH A +LLEAGA V + Sbjct: 534 LHIAVNKGHLQVVKTLLDFGCHPSLQDSEGDTPLHDAISKKRDDILAVLLEAGADVTITN 593 Query: 384 KNKNTPLHYAAGYGRKECVDLLLK---HGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 N LH+AA G + +LL V + DG T + +A LNN EV +LL Sbjct: 594 NNGFNALHHAALRGNPSAMRVLLSKLPRPWIVDEKKDDGYTALHLAALNNHVEVAELL 651 Score = 51.6 bits (122), Expect = 2e-06 Identities = 39/140 (27%), Positives = 65/140 (46%), Gaps = 4/140 (2%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADK---DEEDSEGRRALHFACGYGEFKCAEILLEAG-AAV 397 +HH A G+ ++ L DE+ +G ALH A + AE+L+ G A + Sbjct: 600 LHHAALRGNPSAMRVLLSKLPRPWIVDEKKDDGYTALHLAALNNHVEVAELLVHQGNANL 659 Query: 396 DAMDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLLE 217 D + N+ T LH A + V LL++ GA + +Q+ DG TP+ A ++ L+ L+ Sbjct: 660 DIQNVNQQTALHLAVERQHTQIVRLLVRAGAKLDIQDKDGDTPLHEALRHHTLSQLRQLQ 719 Query: 216 KDVFL*IASLGSHEETWPSS 157 + +G + W S Sbjct: 720 D-----MQDVGKVDAAWEPS 734 Score = 36.2 bits (82), Expect = 0.091 Identities = 22/86 (25%), Positives = 42/86 (48%) Frame = -1 Query: 477 GRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLLKHGAAV 298 G A+ A G ++LL+ V+A DK+ + +H+AA +++L + A + Sbjct: 464 GHTAMQAASQNGHVDILKLLLKQNVDVEAEDKDGDRAVHHAAFGDEGAVIEVLHRGSADL 523 Query: 297 TLQNMDGKTPIDVAKLNNQDEVLKLL 220 +N +TP+ +A +V+K L Sbjct: 524 NARNKRRQTPLHIAVNKGHLQVVKTL 549
>ANKK1_HUMAN (Q8NFD2) Ankyrin repeat and protein kinase domain-containing| protein 1 (EC 2.7.11.1) (Protein kinase PKK2) (X-kinase) (SgK288) Length = 765 Score = 63.2 bits (152), Expect = 7e-10 Identities = 37/96 (38%), Positives = 50/96 (52%) Frame = -1 Query: 507 GADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECV 328 GAD + D +G LHFA G+ A +LL+ GA VDA ++ TPLH AA + Sbjct: 418 GADANRVDEDGWAPLHFAAQNGDDGTARLLLDHGACVDAQEREGWTPLHLAAQNNFENVA 477 Query: 327 DLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 LL+ A L +GKTP+ VA ++KLL Sbjct: 478 RLLVSRQADPNLHEAEGKTPLHVAAYFGHVSLVKLL 513 Score = 62.4 bits (150), Expect = 1e-09 Identities = 37/115 (32%), Positives = 59/115 (51%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMD 385 +H A G +K GA+ D + R LH A G+ + + LL++GA DA+D Sbjct: 498 LHVAAYFGHVSLVKLLTSQGAELDAQQRNLRTPLHLAVERGKVRAIQHLLKSGAVPDALD 557 Query: 384 KNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 ++ PLH AA G+ +LL++GA++ L G TP+ +A E++ LL Sbjct: 558 QSGYGPLHTAAARGKYLICKMLLRYGASLELPTHQGWTPLHLAAYKGHLEIIHLL 612 Score = 58.2 bits (139), Expect = 2e-08 Identities = 34/114 (29%), Positives = 54/114 (47%), Gaps = 1/114 (0%) Frame = -1 Query: 558 HTASVGDGEGLKKAL-DGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDK 382 H A+ + E + + L AD + ++EG+ LH A +G ++L GA +DA + Sbjct: 466 HLAAQNNFENVARLLVSRQADPNLHEAEGKTPLHVAAYFGHVSLVKLLTSQGAELDAQQR 525 Query: 381 NKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 N TPLH A G+ + LLK GA + G P+ A + + K+L Sbjct: 526 NLRTPLHLAVERGKVRAIQHLLKSGAVPDALDQSGYGPLHTAAARGKYLICKML 579 Score = 56.2 bits (134), Expect = 8e-08 Identities = 37/115 (32%), Positives = 55/115 (47%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMD 385 +H + G E ++ L D D + + G L A + +LL GA + +D Sbjct: 366 LHFLVAQGSVEQVRLLLAHEVDVDCQTASGYTPLLIAAQDQQPDLCALLLAHGADANRVD 425 Query: 384 KNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 ++ PLH+AA G LLL HGA V Q +G TP+ +A NN + V +LL Sbjct: 426 EDGWAPLHFAAQNGDDGTARLLLDHGACVDAQEREGWTPLHLAAQNNFENVARLL 480 Score = 52.4 bits (124), Expect = 1e-06 Identities = 33/103 (32%), Positives = 47/103 (45%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMD 385 +H A GD + LD GA D ++ EG LH A A +L+ A + + Sbjct: 432 LHFAAQNGDDGTARLLLDHGACVDAQEREGWTPLHLAAQNNFENVARLLVSRQADPNLHE 491 Query: 384 KNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVA 256 TPLH AA +G V LL GA + Q + +TP+ +A Sbjct: 492 AEGKTPLHVAAYFGHVSLVKLLTSQGAELDAQQRNLRTPLHLA 534 Score = 48.1 bits (113), Expect = 2e-05 Identities = 32/115 (27%), Positives = 51/115 (44%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMD 385 +H G ++ L GA D D G LH A G++ ++LL GA+++ Sbjct: 531 LHLAVERGKVRAIQHLLKSGAVPDALDQSGYGPLHTAAARGKYLICKMLLRYGASLELPT 590 Query: 384 KNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 TPLH AA G E + LL + A + TP+ +A + ++ V+ L Sbjct: 591 HQGWTPLHLAAYKGHLEIIHLLAESHANMGALGAVNWTPLHLAARHGEEAVVSAL 645 Score = 47.0 bits (110), Expect = 5e-05 Identities = 34/116 (29%), Positives = 53/116 (45%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMD 385 +H A G+ + L GAD + + G LH A F LLE A V A + Sbjct: 630 LHLAARHGEEAVVSALLQCGADPNAAEQSGWTPLHLAVQRSTFLSVINLLEHHANVHARN 689 Query: 384 KNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLLE 217 K TP H AA G + +L++ GA + +Q+ TP+ +A + + ++ LE Sbjct: 690 KVGWTPAHLAALKGNTAILKVLVEAGAQLDVQDGVSCTPLQLALRSRKQGIMSFLE 745 Score = 45.4 bits (106), Expect = 1e-04 Identities = 32/103 (31%), Positives = 46/103 (44%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMD 385 +H A+ G K L GA + +G LH A G + +L E+ A + A+ Sbjct: 564 LHTAAARGKYLICKMLLRYGASLELPTHQGWTPLHLAAYKGHLEIIHLLAESHANMGALG 623 Query: 384 KNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVA 256 TPLH AA +G + V LL+ GA G TP+ +A Sbjct: 624 AVNWTPLHLAARHGEEAVVSALLQCGADPNAAEQSGWTPLHLA 666 Score = 40.8 bits (94), Expect = 0.004 Identities = 22/55 (40%), Positives = 29/55 (52%) Frame = -1 Query: 384 KNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 +NK TPLH+ G E V LLL H V Q G TP+ +A + Q ++ LL Sbjct: 360 ENKVTPLHFLVAQGSVEQVRLLLAHEVDVDCQTASGYTPLLIAAQDQQPDLCALL 414
>ILK2_HUMAN (P57043) Integrin-linked protein kinase 2 (EC 2.7.11.1) (ILK-2)| Length = 452 Score = 62.8 bits (151), Expect = 9e-10 Identities = 31/90 (34%), Positives = 49/90 (54%) Frame = -1 Query: 501 DKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDL 322 D ++ D G LH+AC G E+L+ GA ++ M++ +TPLH AA +G ++ V Sbjct: 26 DLNQGDDHGFSPLHWACREGRSAVVEMLIMRGARINVMNRGDDTPLHLAASHGHRDIVQK 85 Query: 321 LLKHGAAVTLQNMDGKTPIDVAKLNNQDEV 232 LL++ A + N G P+ A QD+V Sbjct: 86 LLQYKADINAVNEHGNVPLHYACFWGQDQV 115 Score = 53.1 bits (126), Expect = 7e-07 Identities = 27/84 (32%), Positives = 50/84 (59%) Frame = -1 Query: 465 LHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQN 286 LH A +G + LL+ A ++A++++ N PLHYA +G+ + + L+ +GA V++ N Sbjct: 71 LHLAASHGHRDIVQKLLQYKADINAVNEHGNVPLHYACFWGQDQVAEDLVANGALVSICN 130 Query: 285 MDGKTPIDVAKLNNQDEVLKLLEK 214 G+ P+D AK ++ + + EK Sbjct: 131 KYGEMPVDKAKAPLRELLRERAEK 154 Score = 37.7 bits (86), Expect = 0.031 Identities = 20/58 (34%), Positives = 34/58 (58%), Gaps = 1/58 (1%) Frame = -1 Query: 387 DKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLN-NQDEVLKLLE 217 D + +PLH+A GR V++L+ GA + + N TP+ +A + ++D V KLL+ Sbjct: 31 DDHGFSPLHWACREGRSAVVEMLIMRGARINVMNRGDDTPLHLAASHGHRDIVQKLLQ 88
>ILK1_HUMAN (Q13418) Integrin-linked protein kinase 1 (EC 2.7.11.1) (ILK-1) (59| kDa serine/threonine-protein kinase) (p59ILK) Length = 452 Score = 62.8 bits (151), Expect = 9e-10 Identities = 31/90 (34%), Positives = 49/90 (54%) Frame = -1 Query: 501 DKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDL 322 D ++ D G LH+AC G E+L+ GA ++ M++ +TPLH AA +G ++ V Sbjct: 26 DLNQGDDHGFSPLHWACREGRSAVVEMLIMRGARINVMNRGDDTPLHLAASHGHRDIVQK 85 Query: 321 LLKHGAAVTLQNMDGKTPIDVAKLNNQDEV 232 LL++ A + N G P+ A QD+V Sbjct: 86 LLQYKADINAVNEHGNVPLHYACFWGQDQV 115 Score = 53.1 bits (126), Expect = 7e-07 Identities = 27/84 (32%), Positives = 50/84 (59%) Frame = -1 Query: 465 LHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQN 286 LH A +G + LL+ A ++A++++ N PLHYA +G+ + + L+ +GA V++ N Sbjct: 71 LHLAASHGHRDIVQKLLQYKADINAVNEHGNVPLHYACFWGQDQVAEDLVANGALVSICN 130 Query: 285 MDGKTPIDVAKLNNQDEVLKLLEK 214 G+ P+D AK ++ + + EK Sbjct: 131 KYGEMPVDKAKAPLRELLRERAEK 154 Score = 37.7 bits (86), Expect = 0.031 Identities = 20/58 (34%), Positives = 34/58 (58%), Gaps = 1/58 (1%) Frame = -1 Query: 387 DKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLN-NQDEVLKLLE 217 D + +PLH+A GR V++L+ GA + + N TP+ +A + ++D V KLL+ Sbjct: 31 DDHGFSPLHWACREGRSAVVEMLIMRGARINVMNRGDDTPLHLAASHGHRDIVQKLLQ 88
>ILK_CAVPO (P57044) Integrin-linked protein kinase (EC 2.7.11.1)| (Beta-integrin-linked kinase) Length = 451 Score = 62.8 bits (151), Expect = 9e-10 Identities = 31/90 (34%), Positives = 49/90 (54%) Frame = -1 Query: 501 DKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDL 322 D ++ D G LH+AC G E+L+ GA ++ M++ +TPLH AA +G ++ V Sbjct: 26 DLNQGDDHGFSPLHWACREGRSAVVEMLIMRGARINVMNRGDDTPLHLAASHGHRDIVQK 85 Query: 321 LLKHGAAVTLQNMDGKTPIDVAKLNNQDEV 232 LL++ A + N G P+ A QD+V Sbjct: 86 LLQYKADINAVNEHGNVPLHYACFWGQDQV 115 Score = 52.4 bits (124), Expect = 1e-06 Identities = 27/84 (32%), Positives = 50/84 (59%) Frame = -1 Query: 465 LHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQN 286 LH A +G + LL+ A ++A++++ N PLHYA +G+ + + L+ +GA V++ N Sbjct: 71 LHLAASHGHRDIVQKLLQYKADINAVNEHGNVPLHYACFWGQDQVAEDLVANGALVSICN 130 Query: 285 MDGKTPIDVAKLNNQDEVLKLLEK 214 G+ P+D AK ++ + + EK Sbjct: 131 KYGEMPMDKAKAPLRELLRERAEK 154 Score = 37.7 bits (86), Expect = 0.031 Identities = 20/58 (34%), Positives = 34/58 (58%), Gaps = 1/58 (1%) Frame = -1 Query: 387 DKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLN-NQDEVLKLLE 217 D + +PLH+A GR V++L+ GA + + N TP+ +A + ++D V KLL+ Sbjct: 31 DDHGFSPLHWACREGRSAVVEMLIMRGARINVMNRGDDTPLHLAASHGHRDIVQKLLQ 88
>CTTB2_CALJA (Q2QLF8) Cortactin-binding protein 2 (CortBP2)| Length = 1662 Score = 62.8 bits (151), Expect = 9e-10 Identities = 37/96 (38%), Positives = 51/96 (53%) Frame = -1 Query: 507 GADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECV 328 G D + +G AL+ A G C +LL A A V+A DKN TPL AA G ECV Sbjct: 733 GLDINYSCEDGHSALYSAAKNGHTDCVRLLLSAEAQVNAADKNGFTPLCAAAAQGHFECV 792 Query: 327 DLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 +LL+ + A + G+TP+ +A N E ++LL Sbjct: 793 ELLIAYDANINHAADGGQTPLYLACKNGNKECIRLL 828 Score = 58.9 bits (141), Expect = 1e-08 Identities = 36/117 (30%), Positives = 55/117 (47%) Frame = -1 Query: 570 SIVHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDA 391 S ++ A G + ++ L A + D G L A G F+C E+L+ A ++ Sbjct: 745 SALYSAAKNGHTDCVRLLLSAEAQVNAADKNGFTPLCAAAAQGHFECVELLIAYDANINH 804 Query: 390 MDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 TPL+ A G KEC+ LLL+ G +++ DG TP+ A + LKLL Sbjct: 805 AADGGQTPLYLACKNGNKECIRLLLEAGTDRSVKTTDGWTPVHAAVDTGNVDSLKLL 861 Score = 37.4 bits (85), Expect = 0.041 Identities = 19/56 (33%), Positives = 28/56 (50%) Frame = -1 Query: 477 GRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLLKH 310 G+ L+ AC G +C +LLEAG + TP+H A G + + LL+ H Sbjct: 809 GQTPLYLACKNGNKECIRLLLEAGTDRSVKTTDGWTPVHAAVDTGNVDSLKLLMYH 864 Score = 33.9 bits (76), Expect = 0.45 Identities = 21/68 (30%), Positives = 35/68 (51%) Frame = -1 Query: 423 ILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNN 244 +L E G ++ ++ ++ L+ AA G +CV LLL A V + +G TP+ A Sbjct: 728 LLNEEGLDINYSCEDGHSALYSAAKNGHTDCVRLLLSAEAQVNAADKNGFTPLCAAAAQG 787 Query: 243 QDEVLKLL 220 E ++LL Sbjct: 788 HFECVELL 795
>ANS4B_MOUSE (Q8K3X6) Ankyrin repeat and SAM domain-containing protein 4B| (Harmonin-interacting ankyrin repeat-containing protein) (Harp) Length = 423 Score = 62.8 bits (151), Expect = 9e-10 Identities = 40/116 (34%), Positives = 54/116 (46%) Frame = -1 Query: 561 HHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDK 382 H AS E LK+A D + D +G A +G + EI+ G D D Sbjct: 6 HQAASDSYLELLKEATK--RDLNLSDEDGMTPTLLAAYHGNLEALEIICSRGGDPDKCDI 63 Query: 381 NKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLLEK 214 NTPLHYAA G C+ L+ GA + + D K+P+D A Q E + LL+K Sbjct: 64 WGNTPLHYAASNGHTHCISFLVNFGANIFALDNDLKSPLDAAASREQKECVALLDK 119 Score = 54.3 bits (129), Expect = 3e-07 Identities = 35/110 (31%), Positives = 49/110 (44%) Frame = -1 Query: 543 GDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPL 364 G+ E L+ G D D+ D G LH+A G C L+ GA + A+D + +PL Sbjct: 43 GNLEALEIICSRGGDPDKCDIWGNTPLHYAASNGHTHCISFLVNFGANIFALDNDLKSPL 102 Query: 363 HYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLLEK 214 AA +KECV LL K N T + L N + +K E+ Sbjct: 103 DAAASREQKECVALLDKAATVQNTMNPKRVTRLKEQALKNARKQMKECER 152
>ANS4B_HUMAN (Q8N8V4) Ankyrin repeat and SAM domain-containing protein 4B| (Harmonin-interacting ankyrin repeat-containing protein) (Harp) Length = 460 Score = 62.4 bits (150), Expect = 1e-09 Identities = 40/116 (34%), Positives = 55/116 (47%) Frame = -1 Query: 561 HHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDK 382 H AS E LK+A D + D +G A +G + EI+ G D D Sbjct: 6 HQAASDSYLELLKEATK--RDLNLSDEDGMTPTLLAAYHGNLEALEIICSRGGDPDRCDI 63 Query: 381 NKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLLEK 214 NTPLH+AA G CV L+ GA + + D +TP+D A Q+E + LL+K Sbjct: 64 WGNTPLHFAASNGHAHCVSFLVNFGANIFALDNDLQTPLDAAASREQNECVALLDK 119 Score = 55.1 bits (131), Expect = 2e-07 Identities = 38/101 (37%), Positives = 47/101 (46%) Frame = -1 Query: 543 GDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPL 364 G+ E L+ G D D D G LHFA G C L+ GA + A+D + TPL Sbjct: 43 GNLEALEIICSRGGDPDRCDIWGNTPLHFAASNGHAHCVSFLVNFGANIFALDNDLQTPL 102 Query: 363 HYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQ 241 AA + ECV LL K A T QN+ P V +L Q Sbjct: 103 DAAASREQNECVALLDK---AATAQNI--MNPKKVTRLKEQ 138
>MYPT1_RAT (Q10728) Protein phosphatase 1 regulatory subunit 12A (Myosin| phosphatase-targeting subunit 1) (Myosin phosphatase target subunit 1) (Protein phosphatase myosin-binding subunit) (MBSP) (Serine/threonine protein phosphatase PP1 smooth muscle reg Length = 1032 Score = 62.4 bits (150), Expect = 1e-09 Identities = 37/108 (34%), Positives = 56/108 (51%) Frame = -1 Query: 549 SVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNT 370 S GD + + K L GAD + + +G ALH AC + L+E GA ++ D Sbjct: 49 SSGDTDEVLKLLHRGADINYANVDGLTALHQACIDDNVDMVKFLVENGANINQPDNEGWI 108 Query: 369 PLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLK 226 PLH AA G + + L+ GA V N +G TP+D+A+ +E+L+ Sbjct: 109 PLHAAASCGYLDIAEFLIGQGAHVGAVNSEGDTPLDIAEEEAMEELLQ 156 Score = 46.6 bits (109), Expect = 7e-05 Identities = 29/88 (32%), Positives = 48/88 (54%) Frame = -1 Query: 477 GRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLLKHGAAV 298 G ALH A G + ++L++AG V+ D + TPLH AA +G++E +L+ + + Sbjct: 199 GGTALHVAAAKGYTEVLKLLIQAGYDVNIKDYDGWTPLHAAAHWGKEEACRILVDNLCDM 258 Query: 297 TLQNMDGKTPIDVAKLNNQDEVLKLLEK 214 N G+T DVA +++L LE+ Sbjct: 259 ETVNKVGQTAFDVA----DEDILGYLEE 282
>TNI3K_MOUSE (Q5GIG6) Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1)| (TNNI3-interacting kinase) (Cardiac ankyrin repeat kinase) Length = 833 Score = 62.4 bits (150), Expect = 1e-09 Identities = 38/105 (36%), Positives = 52/105 (49%) Frame = -1 Query: 534 EGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYA 355 E + L GAD + G ALH A G + E+LL+ GA V+ D TPLH A Sbjct: 114 ELITSLLHSGADVQQAGYGGLTALHIAAIAGHPEAVEVLLQHGANVNVQDAVFFTPLHIA 173 Query: 354 AGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 A YG ++ +LLK GA V + G P+ +A ++KLL Sbjct: 174 AYYGHEQVTSVLLKFGADVNVSGEVGDRPLHLASAKGFFNIVKLL 218 Score = 47.8 bits (112), Expect = 3e-05 Identities = 37/120 (30%), Positives = 54/120 (45%), Gaps = 1/120 (0%) Frame = -1 Query: 570 SIVHHTASVGDGEGLKKALD-GGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVD 394 S++H + G + +AL G G ALH A + LL +GA V Sbjct: 68 SLLHLCCACGGNKSHIRALMLKGLRPSRLTRNGFPALHLAVYKDSLELITSLLHSGADVQ 127 Query: 393 AMDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLLEK 214 T LH AA G E V++LL+HGA V +Q+ TP+ +A ++V +L K Sbjct: 128 QAGYGGLTALHIAAIAGHPEAVEVLLQHGANVNVQDAVFFTPLHIAAYYGHEQVTSVLLK 187 Score = 45.8 bits (107), Expect = 1e-04 Identities = 34/121 (28%), Positives = 60/121 (49%), Gaps = 2/121 (1%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMD 385 +H A G E ++ L GA+ + +D+ LH A YG + +LL+ GA V+ Sbjct: 137 LHIAAIAGHPEAVEVLLQHGANVNVQDAVFFTPLHIAAYYGHEQVTSVLLKFGADVNVSG 196 Query: 384 KNKNTPLHYAAGYGRKECVDLLLK-HGAAVTLQNMDGKTPID-VAKLNNQDEVLKLLEKD 211 + + PLH A+ G V LL++ + A V Q+ + P+ ++ + + V LL+ D Sbjct: 197 EVGDRPLHLASAKGFFNIVKLLVEGNKADVNAQDNEDHVPLHFCSRFGHHNIVSYLLQSD 256 Query: 210 V 208 + Sbjct: 257 L 257 Score = 29.6 bits (65), Expect = 8.5 Identities = 24/79 (30%), Positives = 34/79 (43%), Gaps = 4/79 (5%) Frame = -1 Query: 558 HTASVGDGEGLKKALDGG--ADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVD--A 391 H AS + K L G AD + +D+E LHF +G LL++ V Sbjct: 204 HLASAKGFFNIVKLLVEGNKADVNAQDNEDHVPLHFCSRFGHHNIVSYLLQSDLEVQPHV 263 Query: 390 MDKNKNTPLHYAAGYGRKE 334 ++ +TPLH A G E Sbjct: 264 INIYGDTPLHLACYNGNFE 282
>MYPT1_HUMAN (O14974) Protein phosphatase 1 regulatory subunit 12A (Myosin| phosphatase-targeting subunit 1) (Myosin phosphatase target subunit 1) (Protein phosphatase myosin-binding subunit) Length = 1030 Score = 62.4 bits (150), Expect = 1e-09 Identities = 37/108 (34%), Positives = 56/108 (51%) Frame = -1 Query: 549 SVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNT 370 S GD + + K L GAD + + +G ALH AC + L+E GA ++ D Sbjct: 49 SSGDTDEVLKLLHRGADINYANVDGLTALHQACIDDNVDMVKFLVENGANINQPDNEGWI 108 Query: 369 PLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLK 226 PLH AA G + + L+ GA V N +G TP+D+A+ +E+L+ Sbjct: 109 PLHAAASCGYLDIAEFLIGQGAHVGAVNSEGDTPLDIAEEEAMEELLQ 156 Score = 47.8 bits (112), Expect = 3e-05 Identities = 29/88 (32%), Positives = 49/88 (55%) Frame = -1 Query: 477 GRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLLKHGAAV 298 G ALH A G + ++L++AG V+ D + TPLH AA +G++E +L+ + + Sbjct: 199 GGTALHVAAAKGYTEVLKLLIQAGYDVNIKDYDGWTPLHAAAHWGKEEACRILVDNLCDM 258 Query: 297 TLQNMDGKTPIDVAKLNNQDEVLKLLEK 214 + N G+T DVA +++L LE+ Sbjct: 259 EMVNKVGQTAFDVA----DEDILGYLEE 282
>ANKR6_HUMAN (Q9Y2G4) Ankyrin repeat domain-containing protein 6| Length = 692 Score = 62.4 bits (150), Expect = 1e-09 Identities = 38/115 (33%), Positives = 59/115 (51%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMD 385 +H VG+ E + + G D +D +G ALH A +G + A++L++AGA V A + Sbjct: 79 LHRATVVGNTEIIAALIHEGCALDRQDKDGNTALHEASWHGFSQSAKLLVKAGANVLAKN 138 Query: 384 KNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 K NT LH A + +LL G+ L+N G T + VA N +++LL Sbjct: 139 KAGNTALHLACQNSHSQSTRVLLLAGSRADLKNNAGDTCLHVAARYNHLSIIRLL 193 Score = 61.6 bits (148), Expect = 2e-09 Identities = 37/115 (32%), Positives = 58/115 (50%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMD 385 +H A+ G ++ L G D D +D + ALH A G + L+ G A+D D Sbjct: 46 LHLAANKGHLPVVQILLKAGCDLDVQDDGDQTALHRATVVGNTEIIAALIHEGCALDRQD 105 Query: 384 KNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 K+ NT LH A+ +G + LL+K GA V +N G T + +A N+ + ++L Sbjct: 106 KDGNTALHEASWHGFSQSAKLLVKAGANVLAKNKAGNTALHLACQNSHSQSTRVL 160 Score = 56.2 bits (134), Expect = 8e-08 Identities = 35/110 (31%), Positives = 50/110 (45%) Frame = -1 Query: 543 GDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPL 364 G E + + ++ GA + GR LH A G +ILL+AG +D D T L Sbjct: 21 GQTENVVQLINKGA-RVAVTKHGRTPLHLAANKGHLPVVQILLKAGCDLDVQDDGDQTAL 79 Query: 363 HYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLLEK 214 H A G E + L+ G A+ Q+ DG T + A + + KLL K Sbjct: 80 HRATVVGNTEIIAALIHEGCALDRQDKDGNTALHEASWHGFSQSAKLLVK 129 Score = 55.1 bits (131), Expect = 2e-07 Identities = 35/115 (30%), Positives = 53/115 (46%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMD 385 +H + G + K + GA+ ++ G ALH AC + +LL AG+ D + Sbjct: 112 LHEASWHGFSQSAKLLVKAGANVLAKNKAGNTALHLACQNSHSQSTRVLLLAGSRADLKN 171 Query: 384 KNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 +T LH AA Y + LLL +V +N G T + VA N +V K+L Sbjct: 172 NAGDTCLHVAARYNHLSIIRLLLTAFCSVHEKNQAGDTALHVAAALNHKKVAKIL 226 Score = 37.4 bits (85), Expect = 0.041 Identities = 23/60 (38%), Positives = 29/60 (48%) Frame = -1 Query: 492 EEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLLK 313 E++ G ALH A K A+ILLEAGA ++ TPL A + E LL K Sbjct: 202 EKNQAGDTALHVAAALNHKKVAKILLEAGADTTIVNNAGQTPLETARYHNNPEVALLLTK 261
>ASB13_HUMAN (Q8WXK3) Ankyrin repeat and SOCS box protein 13 (ASB-13)| Length = 278 Score = 62.4 bits (150), Expect = 1e-09 Identities = 39/115 (33%), Positives = 62/115 (53%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMD 385 VH A G+ L++ ++ GA ++ + LH A G+ +C ++LL AGA VDA + Sbjct: 23 VHEAAQRGESLQLQQLIESGACVNQVTVDSITPLHAASLQGQARCVQLLLAAGAQVDARN 82 Query: 384 KNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 + +TPL A G ECV LLL +GA V + +P+ A ++ E ++LL Sbjct: 83 IDGSTPLCDACASGSIECVKLLLSYGAKVN-PPLYTASPLHEACMSGSSECVRLL 136 Score = 57.8 bits (138), Expect = 3e-08 Identities = 34/85 (40%), Positives = 48/85 (56%) Frame = -1 Query: 474 RRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLLKHGAAVT 295 R +H A GE + L+E+GA V+ + + TPLH A+ G+ CV LLL GA V Sbjct: 20 RTPVHEAAQRGESLQLQQLIESGACVNQVTVDSITPLHAASLQGQARCVQLLLAAGAQVD 79 Query: 294 LQNMDGKTPIDVAKLNNQDEVLKLL 220 +N+DG TP+ A + E +KLL Sbjct: 80 ARNIDGSTPLCDACASGSIECVKLL 104 Score = 55.8 bits (133), Expect = 1e-07 Identities = 32/103 (31%), Positives = 51/103 (49%) Frame = -1 Query: 570 SIVHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDA 391 S +H G E ++ +D GA+ + D LH AC C ++LL AGA V+A Sbjct: 119 SPLHEACMSGSSECVRLLIDVGANLEAHDCHFGTPLHVACAREHLDCVKVLLNAGANVNA 178 Query: 390 MDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPID 262 K T LH+AA + +++L++ G + ++ GK P D Sbjct: 179 A-KLHETALHHAAKVKNVDLIEMLIEFGGNIYARDNRGKKPSD 220 Score = 52.8 bits (125), Expect = 9e-07 Identities = 29/83 (34%), Positives = 42/83 (50%) Frame = -1 Query: 465 LHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQN 286 LH AC G +C +L++ GA ++A D + TPLH A +CV +LL GA V Sbjct: 121 LHEACMSGSSECVRLLIDVGANLEAHDCHFGTPLHVACAREHLDCVKVLLNAGANVNAAK 180 Query: 285 MDGKTPIDVAKLNNQDEVLKLLE 217 + AK+ N D + L+E Sbjct: 181 LHETALHHAAKVKNVDLIEMLIE 203 Score = 52.0 bits (123), Expect = 2e-06 Identities = 37/114 (32%), Positives = 54/114 (47%), Gaps = 1/114 (0%) Frame = -1 Query: 558 HTASV-GDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDK 382 H AS+ G ++ L GA D + +G L AC G +C ++LL GA V+ Sbjct: 57 HAASLQGQARCVQLLLAAGAQVDARNIDGSTPLCDACASGSIECVKLLLSYGAKVNP-PL 115 Query: 381 NKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 +PLH A G ECV LL+ GA + + TP+ VA + +K+L Sbjct: 116 YTASPLHEACMSGSSECVRLLIDVGANLEAHDCHFGTPLHVACAREHLDCVKVL 169 Score = 33.9 bits (76), Expect = 0.45 Identities = 18/53 (33%), Positives = 27/53 (50%) Frame = -1 Query: 378 KNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 + TP+H AA G + L++ GA V +D TP+ A L Q ++LL Sbjct: 19 ERTPVHEAAQRGESLQLQQLIESGACVNQVTVDSITPLHAASLQGQARCVQLL 71
>ACBD6_MOUSE (Q9D061) Acyl-CoA-binding domain-containing protein 6| Length = 282 Score = 62.4 bits (150), Expect = 1e-09 Identities = 33/82 (40%), Positives = 47/82 (57%) Frame = -1 Query: 504 ADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVD 325 AD + D EGR LH+AC G + ++LL+ A ++ D T LHYAA + V+ Sbjct: 183 ADVNMTDEEGRALLHWACDRGHKELVKVLLQYEAGINCQDNEGQTALHYAAACEFLDIVE 242 Query: 324 LLLKHGAAVTLQNMDGKTPIDV 259 LLL+ GA TL++ DG P +V Sbjct: 243 LLLQSGADPTLRDQDGCLPEEV 264 Score = 36.6 bits (83), Expect = 0.070 Identities = 20/70 (28%), Positives = 37/70 (52%) Frame = -1 Query: 429 AEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKL 250 A+ + A V+ D+ LH+A G KE V +LL++ A + Q+ +G+T + A Sbjct: 175 AKAIKSKAADVNMTDEEGRALLHWACDRGHKELVKVLLQYEAGINCQDNEGQTALHYAAA 234 Query: 249 NNQDEVLKLL 220 ++++LL Sbjct: 235 CEFLDIVELL 244 Score = 33.5 bits (75), Expect = 0.59 Identities = 26/90 (28%), Positives = 42/90 (46%) Frame = -1 Query: 570 SIVHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDA 391 +++H G E +K L A + +D+EG+ ALH+A E+LL++GA Sbjct: 194 ALLHWACDRGHKELVKVLLQYEAGINCQDNEGQTALHYAAACEFLDIVELLLQSGADPTL 253 Query: 390 MDKNKNTPLHYAAGYGRKECVDLLLKHGAA 301 D++ P G K LL +H A+ Sbjct: 254 RDQDGCLPEEVT---GCKAVSLLLQRHRAS 280
>MYPT1_MOUSE (Q9DBR7) Protein phosphatase 1 regulatory subunit 12A (Myosin| phosphatase-targeting subunit 1) (Myosin phosphatase target subunit 1) Length = 1004 Score = 62.4 bits (150), Expect = 1e-09 Identities = 37/108 (34%), Positives = 56/108 (51%) Frame = -1 Query: 549 SVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNT 370 S GD + + K L GAD + + +G ALH AC + L+E GA ++ D Sbjct: 49 SSGDTDEVLKLLHRGADINYANVDGLTALHQACIDDNVDMVKFLVENGANINQPDNEGWI 108 Query: 369 PLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLK 226 PLH AA G + + L+ GA V N +G TP+D+A+ +E+L+ Sbjct: 109 PLHAAASCGYLDIAEFLIGQGAHVGAVNSEGDTPLDIAEEEAMEELLQ 156 Score = 46.6 bits (109), Expect = 7e-05 Identities = 29/88 (32%), Positives = 48/88 (54%) Frame = -1 Query: 477 GRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLLKHGAAV 298 G ALH A G + ++L++AG V+ D + TPLH AA +G++E +L+ + + Sbjct: 199 GGTALHVAAAKGYTEVLKLLIQAGYDVNIKDYDGWTPLHAAAHWGKEEACRILVDNLCDM 258 Query: 297 TLQNMDGKTPIDVAKLNNQDEVLKLLEK 214 N G+T DVA +++L LE+ Sbjct: 259 ETVNKVGQTAFDVA----DEDILGYLEE 282
>MYPT2_MOUSE (Q8BG95) Protein phosphatase 1 regulatory subunit 12B (Myosin| phosphatase-targeting subunit 2) (Fragment) Length = 484 Score = 62.0 bits (149), Expect = 2e-09 Identities = 36/99 (36%), Positives = 52/99 (52%) Frame = -1 Query: 549 SVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNT 370 S GD + +KK L GAD + + +G ALH AC + L+E A V+ D T Sbjct: 67 SSGDTDEVKKLLARGADINTVNVDGLTALHQACIDENLDMVKFLVENRANVNQQDNEGWT 126 Query: 369 PLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAK 253 PLH AA G + + HGA+V + N +G+ P D+A+ Sbjct: 127 PLHAAASCGYLNIAEYFISHGASVGIVNSEGEVPSDLAE 165 Score = 51.2 bits (121), Expect = 3e-06 Identities = 34/102 (33%), Positives = 54/102 (52%), Gaps = 1/102 (0%) Frame = -1 Query: 516 LDGGADKDEEDSE-GRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGR 340 L+ G +D + G ALH A G + +L++AG ++ D + TPLH AA +G Sbjct: 203 LNSGRIEDVRQARSGATALHVAAAKGYSEVLRLLIQAGYELNVQDHDGWTPLHAAAHWGV 262 Query: 339 KECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLLEK 214 KE +L + + ++N G+TP DVA E L++L+K Sbjct: 263 KEACSILAEALCDMDIRNKLGQTPFDVAD-EGLVEHLEMLQK 303
>OSBL1_RAT (Q8K4M9) Oxysterol-binding protein-related protein 1 (OSBP-related| protein 1) (ORP-1) Length = 950 Score = 62.0 bits (149), Expect = 2e-09 Identities = 43/127 (33%), Positives = 70/127 (55%), Gaps = 10/127 (7%) Frame = -1 Query: 567 IVHHTASVGDGEGLKKALDGGADKD---EEDSEGRRA-------LHFACGYGEFKCAEIL 418 ++HH + G+ E ++K L+ A + + D +GR LH AC +G + + L Sbjct: 9 LLHHARN-GNAEEVRKLLEAMARAEVVADIDCKGRSKSNLGWTPLHLACYFGHKQVVQDL 67 Query: 417 LEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQD 238 L+AGA V+ ++ +TPLH AA GRKE V LLL++ A T+ N G+T + + Sbjct: 68 LKAGAKVNMLNDMGDTPLHRAAFTGRKELVMLLLEYNADTTVVNGSGQT---AKEATHDK 124 Query: 237 EVLKLLE 217 E+ ++LE Sbjct: 125 EIRQMLE 131 Score = 42.4 bits (98), Expect = 0.001 Identities = 22/57 (38%), Positives = 33/57 (57%) Frame = -1 Query: 399 VDAMDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVL 229 V+ D+ NTPLH AA K+CV LL+ GA +L+N + + P+D+A +L Sbjct: 169 VNCSDQLGNTPLHCAAYRAHKQCVLKLLRSGADPSLKNKNDQKPLDLAHGTEMKHIL 225
>ILK_MOUSE (O55222) Integrin-linked protein kinase (EC 2.7.11.1)| Length = 452 Score = 61.6 bits (148), Expect = 2e-09 Identities = 31/90 (34%), Positives = 48/90 (53%) Frame = -1 Query: 501 DKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDL 322 D ++ D G LH+AC G E+L+ GA ++ M++ +TPLH AA +G ++ V Sbjct: 26 DLNQGDDHGFSPLHWACREGRSAVVEMLIMRGARINVMNRGDDTPLHLAASHGHRDIVQK 85 Query: 321 LLKHGAAVTLQNMDGKTPIDVAKLNNQDEV 232 LL++ A N G P+ A QD+V Sbjct: 86 LLQYKADTNAVNEHGNVPLHYACFWGQDQV 115 Score = 52.0 bits (123), Expect = 2e-06 Identities = 27/84 (32%), Positives = 49/84 (58%) Frame = -1 Query: 465 LHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQN 286 LH A +G + LL+ A +A++++ N PLHYA +G+ + + L+ +GA V++ N Sbjct: 71 LHLAASHGHRDIVQKLLQYKADTNAVNEHGNVPLHYACFWGQDQVAEDLVANGALVSICN 130 Query: 285 MDGKTPIDVAKLNNQDEVLKLLEK 214 G+ P+D AK ++ + + EK Sbjct: 131 KYGEMPVDKAKAPLRELLRERAEK 154 Score = 37.7 bits (86), Expect = 0.031 Identities = 20/58 (34%), Positives = 34/58 (58%), Gaps = 1/58 (1%) Frame = -1 Query: 387 DKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLN-NQDEVLKLLE 217 D + +PLH+A GR V++L+ GA + + N TP+ +A + ++D V KLL+ Sbjct: 31 DDHGFSPLHWACREGRSAVVEMLIMRGARINVMNRGDDTPLHLAASHGHRDIVQKLLQ 88
>OSBL1_HUMAN (Q9BXW6) Oxysterol-binding protein-related protein 1 (OSBP-related| protein 1) (ORP-1) Length = 950 Score = 61.6 bits (148), Expect = 2e-09 Identities = 40/128 (31%), Positives = 68/128 (53%), Gaps = 10/128 (7%) Frame = -1 Query: 567 IVHHTASVGDGEGLKKALDGGADKD----------EEDSEGRRALHFACGYGEFKCAEIL 418 ++HH + G+ E +++ L+ A + + + G LH AC +G + + L Sbjct: 9 LLHHARN-GNAEEVRQLLETMARNEVIADINCKGRSKSNLGWTPLHLACYFGHRQVVQDL 67 Query: 417 LEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQD 238 L+AGA V+ ++ +TPLH AA GRKE V LLL++ A T+ N G+T +V Sbjct: 68 LKAGAEVNVLNDMGDTPLHRAAFTGRKELVMLLLEYNADTTIVNGSGQTAKEVTHAEEIR 127 Query: 237 EVLKLLEK 214 +L+ +E+ Sbjct: 128 SMLEAVER 135 Score = 40.4 bits (93), Expect = 0.005 Identities = 20/49 (40%), Positives = 30/49 (61%) Frame = -1 Query: 399 VDAMDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAK 253 V+ D+ NTPLH AA K+C LL+ GA L+N + + P+D+A+ Sbjct: 169 VNCSDQLGNTPLHCAAYRAHKQCALKLLRSGADPNLKNKNDQKPLDLAQ 217
>INVS_CANFA (Q6JAN1) Inversin (Inversion of embryo turning protein)| (Nephrocystin-2) Length = 1081 Score = 61.6 bits (148), Expect = 2e-09 Identities = 39/111 (35%), Positives = 60/111 (54%), Gaps = 2/111 (1%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLE--AGAAVDA 391 +H A G+ +K L A+ ++D E LH A + KC +LL+ A VD Sbjct: 85 LHLAAQKGNYRFMKLLLTRRANWMQKDLEEMTPLHLATRHKSPKCLALLLKFMAPGEVDT 144 Query: 390 MDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQD 238 DKNK T LH++A Y E V LL+KH + + + +++GK P+ A N++D Sbjct: 145 QDKNKQTALHWSAYYNNPEHVKLLIKHDSNIGIPDVEGKIPLHWA-ANHKD 194 Score = 59.3 bits (142), Expect = 1e-08 Identities = 42/120 (35%), Positives = 60/120 (50%), Gaps = 1/120 (0%) Frame = -1 Query: 570 SIVHHTASVGDGEGLKKALDGG-ADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVD 394 S VH A GD L + + G A KD+ED GR L + CA+ LL+AGA V+ Sbjct: 16 SQVHAAAINGDKGALHRLIIGNSALKDKEDQFGRTPLMYCVLADRLDCADALLKAGADVN 75 Query: 393 AMDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLLEK 214 D ++ T LH AA G + LLL A ++++ TP+ +A + + L LL K Sbjct: 76 KTDHSQRTALHLAAQKGNYRFMKLLLTRRANWMQKDLEEMTPLHLATRHKSPKCLALLLK 135 Score = 58.5 bits (140), Expect = 2e-08 Identities = 36/100 (36%), Positives = 50/100 (50%) Frame = -1 Query: 519 ALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGR 340 +L D + D G ALH A G ++LLE A VDA D K+TPL A G Sbjct: 343 SLKSDIDINMADKYGGTALHAAALSGHVSTVKLLLENNAQVDATDVMKHTPLFRACEMGH 402 Query: 339 KECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 K+ + L+K GA V L + DG + + A L +V ++L Sbjct: 403 KDVIQTLIKGGARVDLVDQDGHSLLHWAALGGNADVCQIL 442 Score = 51.6 bits (122), Expect = 2e-06 Identities = 35/130 (26%), Positives = 61/130 (46%), Gaps = 2/130 (1%) Frame = -1 Query: 570 SIVHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDA 391 S++H A G+ + + ++ + + +D GR L A G C +L+E A + Sbjct: 425 SLLHWAALGGNADVCQILIENKINPNVQDYAGRTPLQCAAYGGYINCMAVLMENNADPNI 484 Query: 390 MDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTL--QNMDGKTPIDVAKLNNQDEVLKLLE 217 DK T LH++ G + + LLL A N + TP+D A L + EV++ + Sbjct: 485 QDKEGRTALHWSCNNGYLDAIKLLLDFAAFPNQMENNEERYTPLDYALLGERHEVIQFML 544 Query: 216 KDVFL*IASL 187 + L IA++ Sbjct: 545 EHGALSIAAI 554 Score = 49.7 bits (117), Expect = 8e-06 Identities = 31/109 (28%), Positives = 54/109 (49%) Frame = -1 Query: 546 VGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTP 367 +G + ++ + GGA D D +G LH+A G +IL+E + D TP Sbjct: 400 MGHKDVIQTLIKGGARVDLVDQDGHSLLHWAALGGNADVCQILIENKINPNVQDYAGRTP 459 Query: 366 LHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 L AA G C+ +L+++ A +Q+ +G+T + + N + +KLL Sbjct: 460 LQCAAYGGYINCMAVLMENNADPNIQDKEGRTALHWSCNNGYLDAIKLL 508 Score = 49.7 bits (117), Expect = 8e-06 Identities = 35/103 (33%), Positives = 51/103 (49%), Gaps = 2/103 (1%) Frame = -1 Query: 516 LDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRK 337 L GAD ++ D R ALH A G ++ ++LL A D + TPLH A + Sbjct: 68 LKAGADVNKTDHSQRTALHLAAQKGNYRFMKLLLTRRANWMQKDLEEMTPLHLATRHKSP 127 Query: 336 ECVDLLLKHGA--AVTLQNMDGKTPIDVAKLNNQDEVLKLLEK 214 +C+ LLLK A V Q+ + +T + + N E +KLL K Sbjct: 128 KCLALLLKFMAPGEVDTQDKNKQTALHWSAYYNNPEHVKLLIK 170 Score = 48.5 bits (114), Expect = 2e-05 Identities = 29/103 (28%), Positives = 50/103 (48%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMD 385 +H A G +K L+ A D D L AC G + L++ GA VD +D Sbjct: 361 LHAAALSGHVSTVKLLLENNAQVDATDVMKHTPLFRACEMGHKDVIQTLIKGGARVDLVD 420 Query: 384 KNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVA 256 ++ ++ LH+AA G + +L+++ +Q+ G+TP+ A Sbjct: 421 QDGHSLLHWAALGGNADVCQILIENKINPNVQDYAGRTPLQCA 463 Score = 48.1 bits (113), Expect = 2e-05 Identities = 31/94 (32%), Positives = 47/94 (50%), Gaps = 2/94 (2%) Frame = -1 Query: 489 EDSEGRRALHFACGYGEFKCAEILLEAGAA-VDAMDKNKNTPLHYAAGYGRKECVDLLLK 313 +D EGR LHFA G ++L + + + D TPLH+AA G + V LLL+ Sbjct: 217 QDYEGRTPLHFAVADGNVTVVDVLTSYESCNITSYDNLFRTPLHWAALLGHAQIVHLLLE 276 Query: 312 HGAAVTL-QNMDGKTPIDVAKLNNQDEVLKLLEK 214 + T+ + G TP+ A +N E +K+ K Sbjct: 277 RNKSGTIPSDSQGATPLHYAAQSNFAETVKVFLK 310 Score = 46.2 bits (108), Expect = 9e-05 Identities = 39/147 (26%), Positives = 63/147 (42%), Gaps = 3/147 (2%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDA-- 391 +H+ A E +K L + KD+ D EGR + +A G G +L + +D Sbjct: 293 LHYAAQSNFAETVKVFLKHPSVKDDSDLEGRTSFMWAAGKGSDDVLRTMLSLKSDIDINM 352 Query: 390 MDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPI-DVAKLNNQDEVLKLLEK 214 DK T LH AA G V LLL++ A V ++ TP+ ++ ++D + L++ Sbjct: 353 ADKYGGTALHAAALSGHVSTVKLLLENNAQVDATDVMKHTPLFRACEMGHKDVIQTLIKG 412 Query: 213 DVFL*IASLGSHEETWPSSCFTSLWHW 133 + + H SL HW Sbjct: 413 GARVDLVDQDGH----------SLLHW 429 Score = 42.0 bits (97), Expect = 0.002 Identities = 28/90 (31%), Positives = 42/90 (46%), Gaps = 1/90 (1%) Frame = -1 Query: 486 DSEGRRALHFACGYGEFKCAEILLEAG-AAVDAMDKNKNTPLHYAAGYGRKECVDLLLKH 310 D+ R LH+A G + +LLE + D TPLHYAA E V + LKH Sbjct: 252 DNLFRTPLHWAALLGHAQIVHLLLERNKSGTIPSDSQGATPLHYAAQSNFAETVKVFLKH 311 Query: 309 GAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 + +++G+T A D+VL+ + Sbjct: 312 PSVKDDSDLEGRTSFMWAAGKGSDDVLRTM 341 Score = 33.9 bits (76), Expect = 0.45 Identities = 24/91 (26%), Positives = 40/91 (43%), Gaps = 2/91 (2%) Frame = -1 Query: 486 DSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVD--LLLK 313 DS+G LH+A + ++ L+ + D D T +AAG G + + L LK Sbjct: 286 DSQGATPLHYAAQSNFAETVKVFLKHPSVKDDSDLEGRTSFMWAAGKGSDDVLRTMLSLK 345 Query: 312 HGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 + + + G T + A L+ +KLL Sbjct: 346 SDIDINMADKYGGTALHAAALSGHVSTVKLL 376
>GABP3_MOUSE (P81069) GA-binding protein beta-2-1 chain (GABP-beta-2-1 subunit)| (GABPB2-1) Length = 414 Score = 61.6 bits (148), Expect = 2e-09 Identities = 37/119 (31%), Positives = 58/119 (48%) Frame = -1 Query: 570 SIVHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDA 391 S +H A G + L G +D R LH A G E+L+ +GA V+A Sbjct: 40 SPLHLAAQYGHYSTAEVLLRAGVSRDARTKVDRTPLHMAAADGHVHIVELLVRSGADVNA 99 Query: 390 MDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLLEK 214 D + T LH+A + + V+LL+K+GA V + K+ D+A N E+L +L++ Sbjct: 100 KDMLQMTALHWATEHHHRLVVELLIKYGADVYAFSKFDKSAFDIAMEKNNTEILVMLQE 158 Score = 59.3 bits (142), Expect = 1e-08 Identities = 35/88 (39%), Positives = 48/88 (54%) Frame = -1 Query: 477 GRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLLKHGAAV 298 G LH A YG + AE+LL AG + DA K TPLH AA G V+LL++ GA V Sbjct: 38 GTSPLHLAAQYGHYSTAEVLLRAGVSRDARTKVDRTPLHMAAADGHVHIVELLVRSGADV 97 Query: 297 TLQNMDGKTPIDVAKLNNQDEVLKLLEK 214 ++M T + A ++ V++LL K Sbjct: 98 NAKDMLQMTALHWATEHHHRLVVELLIK 125 Score = 34.3 bits (77), Expect = 0.35 Identities = 19/67 (28%), Positives = 33/67 (49%) Frame = -1 Query: 420 LLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQ 241 +L A A D +PLH AA YG ++LL+ G + + +TP+ +A + Sbjct: 24 ILMANGAPFTTDWLGTSPLHLAAQYGHYSTAEVLLRAGVSRDARTKVDRTPLHMAAADGH 83 Query: 240 DEVLKLL 220 +++LL Sbjct: 84 VHIVELL 90
>CTTB2_CALMO (Q2QLB3) Cortactin-binding protein 2 (CortBP2)| Length = 1663 Score = 61.6 bits (148), Expect = 2e-09 Identities = 37/96 (38%), Positives = 50/96 (52%) Frame = -1 Query: 507 GADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECV 328 G D + +G AL+ A G C +LL A A V+A D N TPL AA G ECV Sbjct: 734 GLDINYSCEDGHSALYSAAKNGHTDCVRLLLSAEAQVNAADTNGFTPLCAAAAQGHFECV 793 Query: 327 DLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 +LL+ + A + G+TP+ +A N E +KLL Sbjct: 794 ELLIAYDANINHAAGGGQTPLYLACKNGNKECIKLL 829 Score = 58.5 bits (140), Expect = 2e-08 Identities = 36/117 (30%), Positives = 55/117 (47%) Frame = -1 Query: 570 SIVHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDA 391 S ++ A G + ++ L A + D+ G L A G F+C E+L+ A ++ Sbjct: 746 SALYSAAKNGHTDCVRLLLSAEAQVNAADTNGFTPLCAAAAQGHFECVELLIAYDANINH 805 Query: 390 MDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 TPL+ A G KEC+ LLL+ G ++ DG TP+ A + LKLL Sbjct: 806 AAGGGQTPLYLACKNGNKECIKLLLEAGTDRCVKTTDGWTPVHAAVDTGNVDSLKLL 862 Score = 33.9 bits (76), Expect = 0.45 Identities = 21/68 (30%), Positives = 35/68 (51%) Frame = -1 Query: 423 ILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNN 244 +L E G ++ ++ ++ L+ AA G +CV LLL A V + +G TP+ A Sbjct: 729 LLNEEGLDINYSCEDGHSALYSAAKNGHTDCVRLLLSAEAQVNAADTNGFTPLCAAAAQG 788 Query: 243 QDEVLKLL 220 E ++LL Sbjct: 789 HFECVELL 796
>ASB7_MOUSE (Q91ZU0) Ankyrin repeat and SOCS box protein 7 (ASB-7)| Length = 318 Score = 61.2 bits (147), Expect = 3e-09 Identities = 40/121 (33%), Positives = 65/121 (53%), Gaps = 4/121 (3%) Frame = -1 Query: 570 SIVHHTASVGDGEGLKKALDGGADKDEEDSEGR-RALHFACGYGEFKCAEILLEAGAAVD 394 +++H +A+ G ++ L+ GAD +D G ALH+A +G + A ++LE+ D Sbjct: 49 TLLHFSAARGKERCVRVFLEHGADPTVKDLIGGFTALHYAAMHGRARIARLMLESEYRSD 108 Query: 393 AMDKNKN---TPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKL 223 ++ N TPLH AA YGR V LLL+ A V + G TP+ +A + + +K+ Sbjct: 109 IINAKSNDGWTPLHVAAHYGRDSFVRLLLEFKAEVDPLSDKGTTPLQLAIIRERSSCVKI 168 Query: 222 L 220 L Sbjct: 169 L 169 Score = 57.4 bits (137), Expect = 4e-08 Identities = 36/119 (30%), Positives = 57/119 (47%), Gaps = 4/119 (3%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMD 385 + + GD ++K L+ G + D+ G LHF+ G+ +C + LE GA D Sbjct: 18 IQAAVAAGDVHTVRKMLEQGYSPNGRDANGWTLLHFSAARGKERCVRVFLEHGADPTVKD 77 Query: 384 K-NKNTPLHYAAGYGRKECVDLLLK---HGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 T LHYAA +GR L+L+ + ++ DG TP+ VA +D ++LL Sbjct: 78 LIGGFTALHYAAMHGRARIARLMLESEYRSDIINAKSNDGWTPLHVAAHYGRDSFVRLL 136 Score = 46.6 bits (109), Expect = 7e-05 Identities = 25/68 (36%), Positives = 33/68 (48%) Frame = -1 Query: 489 EDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLLKH 310 + ++G LH A YG +LLE A VD + TPL A R CV +LL H Sbjct: 113 KSNDGWTPLHVAAHYGRDSFVRLLLEFKAEVDPLSDKGTTPLQLAIIRERSSCVKILLDH 172 Query: 309 GAAVTLQN 286 A + +QN Sbjct: 173 NANIDIQN 180 Score = 33.1 bits (74), Expect = 0.77 Identities = 29/134 (21%), Positives = 49/134 (36%), Gaps = 31/134 (23%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMD 385 +H A G ++ L+ A+ D +G L A C +ILL+ A +D + Sbjct: 121 LHVAAHYGRDSFVRLLLEFKAEVDPLSDKGTTPLQLAIIRERSSCVKILLDHNANIDIQN 180 Query: 384 -------------------------------KNKNTPLHYAAGYGRKECVDLLLKHGAAV 298 ++ TPLH +A C +L +GA Sbjct: 181 GFLLRYAVIKSNHSYCRMFLQRGADTNLGRLEDGQTPLHLSALRDDVLCARMLYNYGADT 240 Query: 297 TLQNMDGKTPIDVA 256 +N +G+TP+ V+ Sbjct: 241 NTRNYEGQTPLAVS 254
>ASB7_MACFA (Q9BGT9) Ankyrin repeat and SOCS box protein 7 (ASB-7)| Length = 318 Score = 61.2 bits (147), Expect = 3e-09 Identities = 40/121 (33%), Positives = 65/121 (53%), Gaps = 4/121 (3%) Frame = -1 Query: 570 SIVHHTASVGDGEGLKKALDGGADKDEEDSEGR-RALHFACGYGEFKCAEILLEAGAAVD 394 +++H +A+ G ++ L+ GAD +D G ALH+A +G + A ++LE+ D Sbjct: 49 TLLHFSAARGKERCVRVFLEHGADPTVKDLIGGFTALHYAAMHGRARIARLMLESEYRSD 108 Query: 393 AMDKNKN---TPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKL 223 ++ N TPLH AA YGR V LLL+ A V + G TP+ +A + + +K+ Sbjct: 109 IINAKSNDGWTPLHVAAHYGRDSFVRLLLEFKAEVDPLSDKGTTPLQLAIIRERSSCVKI 168 Query: 222 L 220 L Sbjct: 169 L 169 Score = 57.4 bits (137), Expect = 4e-08 Identities = 36/119 (30%), Positives = 57/119 (47%), Gaps = 4/119 (3%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMD 385 + + GD ++K L+ G + D+ G LHF+ G+ +C + LE GA D Sbjct: 18 IQAAVAAGDVHTVRKMLEQGYSPNGRDANGWTLLHFSAARGKERCVRVFLEHGADPTVKD 77 Query: 384 K-NKNTPLHYAAGYGRKECVDLLLK---HGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 T LHYAA +GR L+L+ + ++ DG TP+ VA +D ++LL Sbjct: 78 LIGGFTALHYAAMHGRARIARLMLESEYRSDIINAKSNDGWTPLHVAAHYGRDSFVRLL 136 Score = 46.6 bits (109), Expect = 7e-05 Identities = 25/68 (36%), Positives = 33/68 (48%) Frame = -1 Query: 489 EDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLLKH 310 + ++G LH A YG +LLE A VD + TPL A R CV +LL H Sbjct: 113 KSNDGWTPLHVAAHYGRDSFVRLLLEFKAEVDPLSDKGTTPLQLAIIRERSSCVKILLDH 172 Query: 309 GAAVTLQN 286 A + +QN Sbjct: 173 NANIDIQN 180 Score = 33.1 bits (74), Expect = 0.77 Identities = 29/134 (21%), Positives = 49/134 (36%), Gaps = 31/134 (23%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMD 385 +H A G ++ L+ A+ D +G L A C +ILL+ A +D + Sbjct: 121 LHVAAHYGRDSFVRLLLEFKAEVDPLSDKGTTPLQLAIIRERSSCVKILLDHNANIDIQN 180 Query: 384 -------------------------------KNKNTPLHYAAGYGRKECVDLLLKHGAAV 298 ++ TPLH +A C +L +GA Sbjct: 181 GFLLRYAVIKSNHSYCRMFLQRGADTDLGRLEDGQTPLHLSALRDDVLCARMLYNYGADT 240 Query: 297 TLQNMDGKTPIDVA 256 +N +G+TP+ V+ Sbjct: 241 NTRNYEGQTPLAVS 254
>ASB7_HUMAN (Q9H672) Ankyrin repeat and SOCS box protein 7 (ASB-7)| Length = 318 Score = 61.2 bits (147), Expect = 3e-09 Identities = 40/121 (33%), Positives = 65/121 (53%), Gaps = 4/121 (3%) Frame = -1 Query: 570 SIVHHTASVGDGEGLKKALDGGADKDEEDSEGR-RALHFACGYGEFKCAEILLEAGAAVD 394 +++H +A+ G ++ L+ GAD +D G ALH+A +G + A ++LE+ D Sbjct: 49 TLLHFSAARGKERCVRVFLEHGADPTVKDLIGGFTALHYAAMHGRARIARLMLESEYRSD 108 Query: 393 AMDKNKN---TPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKL 223 ++ N TPLH AA YGR V LLL+ A V + G TP+ +A + + +K+ Sbjct: 109 IINAKSNDGWTPLHVAAHYGRDSFVRLLLEFKAEVDPLSDKGTTPLQLAIIRERSSCVKI 168 Query: 222 L 220 L Sbjct: 169 L 169 Score = 57.4 bits (137), Expect = 4e-08 Identities = 36/119 (30%), Positives = 57/119 (47%), Gaps = 4/119 (3%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMD 385 + + GD ++K L+ G + D+ G LHF+ G+ +C + LE GA D Sbjct: 18 IQAAVAAGDVHTVRKMLEQGYSPNGRDANGWTLLHFSAARGKERCVRVFLEHGADPTVKD 77 Query: 384 K-NKNTPLHYAAGYGRKECVDLLLK---HGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 T LHYAA +GR L+L+ + ++ DG TP+ VA +D ++LL Sbjct: 78 LIGGFTALHYAAMHGRARIARLMLESEYRSDIINAKSNDGWTPLHVAAHYGRDSFVRLL 136 Score = 46.6 bits (109), Expect = 7e-05 Identities = 25/68 (36%), Positives = 33/68 (48%) Frame = -1 Query: 489 EDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLLKH 310 + ++G LH A YG +LLE A VD + TPL A R CV +LL H Sbjct: 113 KSNDGWTPLHVAAHYGRDSFVRLLLEFKAEVDPLSDKGTTPLQLAIIRERSSCVKILLDH 172 Query: 309 GAAVTLQN 286 A + +QN Sbjct: 173 NANIDIQN 180 Score = 33.1 bits (74), Expect = 0.77 Identities = 29/134 (21%), Positives = 49/134 (36%), Gaps = 31/134 (23%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMD 385 +H A G ++ L+ A+ D +G L A C +ILL+ A +D + Sbjct: 121 LHVAAHYGRDSFVRLLLEFKAEVDPLSDKGTTPLQLAIIRERSSCVKILLDHNANIDIQN 180 Query: 384 -------------------------------KNKNTPLHYAAGYGRKECVDLLLKHGAAV 298 ++ TPLH +A C +L +GA Sbjct: 181 GFLLRYAVIKSNHSYCRMFLQRGADTNLGRLEDGQTPLHLSALRDDVLCARMLYNYGADT 240 Query: 297 TLQNMDGKTPIDVA 256 +N +G+TP+ V+ Sbjct: 241 NTRNYEGQTPLAVS 254
>AKR1_MORAP (Q9UVH3) Palmitoyltransferase AKR1 (EC 2.3.1.-) (Ankyrin| repeat-containing protein AKR1) (Fragment) Length = 559 Score = 61.2 bits (147), Expect = 3e-09 Identities = 31/81 (38%), Positives = 46/81 (56%) Frame = -1 Query: 495 DEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLL 316 D D+ G +L +A G+ +ILL+ GA VD D+ TPLH+A G +EC+ +L Sbjct: 37 DTADTLGHTSLMWAAYQGDSLSVQILLKHGARVDTKDREGFTPLHWAVVKGNRECLSKIL 96 Query: 315 KHGAAVTLQNMDGKTPIDVAK 253 GA + + GKTP+D+ K Sbjct: 97 MAGADIKAGDKSGKTPVDMIK 117 Score = 47.4 bits (111), Expect = 4e-05 Identities = 33/88 (37%), Positives = 43/88 (48%), Gaps = 1/88 (1%) Frame = -1 Query: 489 EDSEGRRALHFACGYGEFKCAEILLEAGAA-VDAMDKNKNTPLHYAAGYGRKECVDLLLK 313 +DS+G ALH A LL AG VD D +T L +AA G V +LLK Sbjct: 5 QDSQGFNALHLATHSSNAMLVLYLLMAGEMPVDTADTLGHTSLMWAAYQGDSLSVQILLK 64 Query: 312 HGAAVTLQNMDGKTPIDVAKLNNQDEVL 229 HGA V ++ +G TP+ A + E L Sbjct: 65 HGARVDTKDREGFTPLHWAVVKGNRECL 92 Score = 40.4 bits (93), Expect = 0.005 Identities = 23/60 (38%), Positives = 32/60 (53%) Frame = -1 Query: 543 GDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPL 364 GD ++ L GA D +D EG LH+A G +C +L AGA + A DK+ TP+ Sbjct: 54 GDSLSVQILLKHGARVDTKDREGFTPLHWAVVKGNRECLSKILMAGADIKAGDKSGKTPV 113
>PP16B_BOVIN (Q95N27) Protein phosphatase 1 regulatory inhibitor subunit 16B| (TGF-beta-inhibited membrane-associated protein) (bTIMAP) (CAAX box protein TIMAP) Length = 568 Score = 61.2 bits (147), Expect = 3e-09 Identities = 34/96 (35%), Positives = 54/96 (56%) Frame = -1 Query: 507 GADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECV 328 G D D D++G LH A G + AE+LL+ G VD D + PLH AA +G+ + Sbjct: 219 GQDLDWVDAQGATLLHIAGANGYLRAAELLLDHGVRVDVKDWDGWEPLHAAAFWGQMQMA 278 Query: 327 DLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 +LL+ HGA+++ + + PID+ ++E K+L Sbjct: 279 ELLVSHGASLSARTSMDEMPIDLC----EEEEFKVL 310 Score = 52.0 bits (123), Expect = 2e-06 Identities = 32/96 (33%), Positives = 47/96 (48%) Frame = -1 Query: 540 DGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLH 361 D E ++ L D + +G ALH C + ++LL GA V+A D TPLH Sbjct: 80 DAEEVRYFLKNKVSPDLCNEDGLTALHQCCIDNFEEIVKLLLSHGANVNAKDNELWTPLH 139 Query: 360 YAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAK 253 AA G V +L+++GA + N DG P D+ + Sbjct: 140 AAATCGHINLVKILVQYGADLLAVNSDGNMPYDLCE 175 Score = 40.0 bits (92), Expect = 0.006 Identities = 22/67 (32%), Positives = 34/67 (50%) Frame = -1 Query: 420 LLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQ 241 ++ AG +D +D T LH A G +LLL HG V +++ DG P+ A Q Sbjct: 215 MIAAGQDLDWVDAQGATLLHIAGANGYLRAAELLLDHGVRVDVKDWDGWEPLHAAAFWGQ 274 Query: 240 DEVLKLL 220 ++ +LL Sbjct: 275 MQMAELL 281 Score = 30.8 bits (68), Expect = 3.8 Identities = 27/88 (30%), Positives = 39/88 (44%), Gaps = 15/88 (17%) Frame = -1 Query: 438 FKCAEILLEAGAAVDAMD-----KNKNTP----------LHYAAGYGRKECVDLLLKHGA 304 F+ + LLEA DA + KNK +P LH +E V LLL HGA Sbjct: 66 FEASVALLEASLRNDAEEVRYFLKNKVSPDLCNEDGLTALHQCCIDNFEEIVKLLLSHGA 125 Query: 303 AVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 V ++ + TP+ A ++K+L Sbjct: 126 NVNAKDNELWTPLHAAATCGHINLVKIL 153
>IKBE_MOUSE (O54910) NF-kappa-B inhibitor epsilon (NF-kappa-BIE)| (I-kappa-B-epsilon) (IkappaBepsilon) (IKB-epsilon) (IKB-E) Length = 364 Score = 61.2 bits (147), Expect = 3e-09 Identities = 38/89 (42%), Positives = 49/89 (55%), Gaps = 1/89 (1%) Frame = -1 Query: 516 LDGGADKD-EEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGR 340 L GAD D +E + G+ ALH A E + LL+AGA VDA N TPLH AAG G Sbjct: 254 LQNGADIDVQEGTSGKTALHLAVETQERSLVQFLLQAGARVDARMLNGCTPLHLAAGRGL 313 Query: 339 KECVDLLLKHGAAVTLQNMDGKTPIDVAK 253 L + GA L N++ +TP D+A+ Sbjct: 314 NSISSTLCEAGADSLLLNVEDETPQDLAE 342 Score = 36.2 bits (82), Expect = 0.091 Identities = 31/107 (28%), Positives = 47/107 (43%), Gaps = 11/107 (10%) Frame = -1 Query: 507 GADKDEEDSEGRRALHFACGYGEFKCAEILLE--------AGAAVDAMDKNKN--TPLHY 358 GA + +D G ALH AC CA LLE +D KN LH Sbjct: 181 GASRILQDQHGDTALHVACRRQNLACACCLLEEQPEPGRQLSHPLDLQLKNWQGLACLHI 240 Query: 357 AAGYGRKECVDLLLKHGAAVTLQ-NMDGKTPIDVAKLNNQDEVLKLL 220 A + ++LLL++GA + +Q GKT + +A + +++ L Sbjct: 241 ATLQRNQPLIELLLQNGADIDVQEGTSGKTALHLAVETQERSLVQFL 287
>Y045_METMA (Q8Q0U0) Hypothetical ANK-repeat protein MM0045| Length = 360 Score = 61.2 bits (147), Expect = 3e-09 Identities = 34/101 (33%), Positives = 59/101 (58%) Frame = -1 Query: 516 LDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRK 337 + GAD + +D+ G+ AL A G E+L+ AGA ++ DKN NT L YAA G + Sbjct: 220 IKAGADLNIQDNSGKTALVAATKIGHKGIVELLVNAGADLNLQDKNGNTALIYAADRGYR 279 Query: 336 ECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLLEK 214 + V+LL++ GA++ + + G T + + + ++++LL K Sbjct: 280 DIVNLLIEGGASLNIPDEAGLTALMFSAQTGRKDIVELLIK 320 Score = 57.4 bits (137), Expect = 4e-08 Identities = 34/111 (30%), Positives = 57/111 (51%) Frame = -1 Query: 552 ASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKN 373 A + G+ + + GAD + +D G AL FA G A+ L++AG ++ D+N Sbjct: 142 AKIERGDIIDLLVKNGADLNFQDENGETALKFAVKVGYKNIADQLIDAGTDLNIQDENGE 201 Query: 372 TPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 T L AA ++ +LL+K GA + +Q+ GKT + A +++LL Sbjct: 202 TALICAADRAHRDIAELLIKAGADLNIQDNSGKTALVAATKIGHKGIVELL 252 Score = 53.1 bits (126), Expect = 7e-07 Identities = 32/99 (32%), Positives = 50/99 (50%) Frame = -1 Query: 516 LDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRK 337 +D G D + +D G AL A AE+L++AGA ++ D + T L A G K Sbjct: 187 IDAGTDLNIQDENGETALICAADRAHRDIAELLIKAGADLNIQDNSGKTALVAATKIGHK 246 Query: 336 ECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 V+LL+ GA + LQ+ +G T + A +++ LL Sbjct: 247 GIVELLVNAGADLNLQDKNGNTALIYAADRGYRDIVNLL 285 Score = 52.8 bits (125), Expect = 9e-07 Identities = 33/97 (34%), Positives = 53/97 (54%), Gaps = 1/97 (1%) Frame = -1 Query: 543 GDGEGLKKALDGG-ADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTP 367 G E ++K L D + +D+ G+ AL A G +L+E+G +D D+N NT Sbjct: 78 GQTENVEKLLRSNKVDVNYQDAYGKTALISAADKGYRDVIGLLIESGPNLDLQDENGNTA 137 Query: 366 LHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVA 256 L AA R + +DLL+K+GA + Q+ +G+T + A Sbjct: 138 LISAAKIERGDIIDLLVKNGADLNFQDENGETALKFA 174 Score = 46.6 bits (109), Expect = 7e-05 Identities = 26/66 (39%), Positives = 36/66 (54%) Frame = -1 Query: 516 LDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRK 337 ++GGA + D G AL F+ G E+L++AGA ++ DKN T AA G + Sbjct: 286 IEGGASLNIPDEAGLTALMFSAQTGRKDIVELLIKAGADINIEDKNNKTAADLAAEVGFE 345 Query: 336 ECVDLL 319 E VDLL Sbjct: 346 EIVDLL 351 Score = 44.7 bits (104), Expect = 3e-04 Identities = 27/101 (26%), Positives = 49/101 (48%) Frame = -1 Query: 516 LDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRK 337 ++ G + D +D G AL A ++L++ GA ++ D+N T L +A G K Sbjct: 121 IESGPNLDLQDENGNTALISAAKIERGDIIDLLVKNGADLNFQDENGETALKFAVKVGYK 180 Query: 336 ECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLLEK 214 D L+ G + +Q+ +G+T + A ++ +LL K Sbjct: 181 NIADQLIDAGTDLNIQDENGETALICAADRAHRDIAELLIK 221
>PP16A_MOUSE (Q923M0) Protein phosphatase 1 regulatory subunit 16A (Myosin| phosphatase targeting subunit 3) Length = 524 Score = 61.2 bits (147), Expect = 3e-09 Identities = 37/104 (35%), Positives = 58/104 (55%) Frame = -1 Query: 528 LKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAG 349 L+ L GA+ + G LH A G + A +LLE GA++ A D + PLH AA Sbjct: 215 LQNRLQAGANLSDPLDHGATLLHIAAANGFSEVATLLLEQGASLSAKDHDGWEPLHAAAY 274 Query: 348 YGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLLE 217 +G+ V+LL+ HGA + +++ +TP+DV +++ KLLE Sbjct: 275 WGQVHLVELLVAHGADLNGKSLVDETPLDVC--GDEEVRAKLLE 316 Score = 58.5 bits (140), Expect = 2e-08 Identities = 36/100 (36%), Positives = 52/100 (52%) Frame = -1 Query: 552 ASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKN 373 A+ D E +++ L G + + +G ALH C + A+ LL+AGA V+A D Sbjct: 79 AARNDLEEVRQFLTSGVSPNLANEDGLTALHQCCIDDFQEMAQQLLDAGADVNARDSECW 138 Query: 372 TPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAK 253 TPLH AA G V+LL+ GA + N DG P D+ + Sbjct: 139 TPLHAAATCGHLHLVELLISRGADLLAVNSDGNMPYDLCE 178 Score = 36.6 bits (83), Expect = 0.070 Identities = 21/70 (30%), Positives = 33/70 (47%) Frame = -1 Query: 534 EGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYA 355 E ++ LD GAD + DSE LH A G E+L+ GA + A++ + N P Sbjct: 118 EMAQQLLDAGADVNARDSECWTPLHAAATCGHLHLVELLISRGADLLAVNSDGNMPYDLC 177 Query: 354 AGYGRKECVD 325 +C++ Sbjct: 178 EDAQTLDCLE 187
>IKBE_HUMAN (O00221) NF-kappa-B inhibitor epsilon (NF-kappa-BIE)| (I-kappa-B-epsilon) (IkappaBepsilon) (IKB-epsilon) (IKBE) Length = 361 Score = 61.2 bits (147), Expect = 3e-09 Identities = 42/104 (40%), Positives = 56/104 (53%), Gaps = 2/104 (1%) Frame = -1 Query: 558 HTASVGDGEGLKKAL-DGGADKD-EEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMD 385 H A++ + L + L GAD D +E S G+ ALH A E + LL+AGA VDA Sbjct: 236 HIATLQKNQPLMELLLRNGADIDVQEGSSGKTALHLAVETQERGLVQFLLQAGAQVDARM 295 Query: 384 KNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAK 253 N TPLH AAG G L K GA L+N++ +TP D+ + Sbjct: 296 LNGCTPLHLAAGRGLMGISSTLCKAGADSLLRNVEDETPQDLTE 339
>TRPA1_RAT (Q6RI86) Transient receptor potential cation channel subfamily A| member 1 (Ankyrin-like with transmembrane domains protein 1) Length = 1125 Score = 60.8 bits (146), Expect = 3e-09 Identities = 35/96 (36%), Positives = 52/96 (54%), Gaps = 3/96 (3%) Frame = -1 Query: 492 EEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLLK 313 +ED++G LH+AC G LL +V + K+K +PLH+AA YGR LL+ Sbjct: 409 DEDNDGCTPLHYACRQGAPVSVNNLLRFNVSVHSKSKDKKSPLHFAASYGRINTCQRLLQ 468 Query: 312 HGAAVTLQN---MDGKTPIDVAKLNNQDEVLKLLEK 214 + L N + G TP+ +A N D+V++LL K Sbjct: 469 DISDTRLLNEGDLHGMTPLHLAAKNGHDKVVQLLLK 504 Score = 52.8 bits (125), Expect = 9e-07 Identities = 33/121 (27%), Positives = 60/121 (49%), Gaps = 4/121 (3%) Frame = -1 Query: 570 SIVHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLE----AGA 403 S +H GD + +K LD GA D ++ ALHFA G ++++ + Sbjct: 242 SPLHLAVQSGDLDMIKMCLDSGAHIDMMENAKCMALHFAATQGATDIVKLMISSYTGSSD 301 Query: 402 AVDAMDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKL 223 V+A+D N+ T LH A+ + + D L+ GA + + +G++P+ +A + ++ L Sbjct: 302 IVNAVDGNQETLLHRASLFDHHDLADYLISVGADINSTDSEGRSPLILATASASWNIVNL 361 Query: 222 L 220 L Sbjct: 362 L 362 Score = 51.2 bits (121), Expect = 3e-06 Identities = 29/91 (31%), Positives = 48/91 (52%), Gaps = 2/91 (2%) Frame = -1 Query: 486 DSEGRRALHFACGYGEFKCAEILLEAGA--AVDAMDKNKNTPLHYAAGYGRKECVDLLLK 313 + E LH A G+ + ++++ + A++ MD NTPLH+AA + E V LL Sbjct: 61 EDENLCLLHHAAAEGQVELMQLIINGSSCEALNVMDDYGNTPLHWAAEKNQVESVKFLLS 120 Query: 312 HGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 GA L+N + P+ +A +EV+K+L Sbjct: 121 QGANPNLRNRNMMAPLHIAVQGMYNEVIKVL 151 Score = 46.2 bits (108), Expect = 9e-05 Identities = 30/119 (25%), Positives = 57/119 (47%), Gaps = 3/119 (2%) Frame = -1 Query: 567 IVHHTASVGDGEGLKKALDGGADK--DEEDSEGRRALHFACGYGEFKCAEILLEAGAAVD 394 ++HH A+ G E ++ ++G + + + D G LH+A + + + LL GA + Sbjct: 67 LLHHAAAEGQVELMQLIINGSSCEALNVMDDYGNTPLHWAAEKNQVESVKFLLSQGANPN 126 Query: 393 AMDKNKNTPLHYAAGYGRKECVDLLLKHGAA-VTLQNMDGKTPIDVAKLNNQDEVLKLL 220 ++N PLH A E + +L +H A + L+ +G T + + E L++L Sbjct: 127 LRNRNMMAPLHIAVQGMYNEVIKVLTEHKATNINLEGENGNTALMSTCAKDNSEALQIL 185 Score = 43.5 bits (101), Expect = 6e-04 Identities = 31/118 (26%), Positives = 52/118 (44%), Gaps = 3/118 (2%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAM- 388 +H+ G + L + + + LHFA YG + LL+ + + Sbjct: 418 LHYACRQGAPVSVNNLLRFNVSVHSKSKDKKSPLHFAASYGRINTCQRLLQDISDTRLLN 477 Query: 387 --DKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 D + TPLH AA G + V LLLK G A+ L + +G T + A + + +K++ Sbjct: 478 EGDLHGMTPLHLAAKNGHDKVVQLLLKKG-ALFLSDHNGWTALHHASMGGYTQTMKVI 534 Score = 42.7 bits (99), Expect = 0.001 Identities = 27/97 (27%), Positives = 46/97 (47%), Gaps = 8/97 (8%) Frame = -1 Query: 489 EDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLLKH 310 E G AL C + +ILLE GA + +K + P+H AA G K C++L+L + Sbjct: 162 EGENGNTALMSTCAKDNSEALQILLEKGAKLCKSNKWGDYPVHQAAFSGAKRCMELILAY 221 Query: 309 G--------AAVTLQNMDGKTPIDVAKLNNQDEVLKL 223 G A + N +P+ +A + +++K+ Sbjct: 222 GEKTGYSREAHINFVNHKKASPLHLAVQSGDLDMIKM 258 Score = 41.2 bits (95), Expect = 0.003 Identities = 41/156 (26%), Positives = 59/156 (37%), Gaps = 39/156 (25%) Frame = -1 Query: 558 HTASVGDGEGLKKALDG-GADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVD---- 394 H AS+ D L L GAD + DSEGR L A + +LL GA VD Sbjct: 315 HRASLFDHHDLADYLISVGADINSTDSEGRSPLILATASASWNIVNLLLSKGAKVDIKDH 374 Query: 393 --------------------------------AMDKNKN--TPLHYAAGYGRKECVDLLL 316 MD++ + TPLHYA G V+ LL Sbjct: 375 LGRNFLHLTVQQPYGLRNLRPEFLQMQHIKELVMDEDNDGCTPLHYACRQGAPVSVNNLL 434 Query: 315 KHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLLEKDV 208 + +V ++ D K+P+ A + + L +D+ Sbjct: 435 RFNVSVHSKSKDKKSPLHFAASYGRINTCQRLLQDI 470
>PP16B_HUMAN (Q96T49) Protein phosphatase 1 regulatory inhibitor subunit 16B| (TGF-beta-inhibited membrane-associated protein) (hTIMAP) (CAAX box protein TIMAP) (Ankyrin repeat domain protein 4) Length = 567 Score = 60.8 bits (146), Expect = 3e-09 Identities = 34/96 (35%), Positives = 54/96 (56%) Frame = -1 Query: 507 GADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECV 328 G D D D++G LH A G + AE+LL+ G VD D + PLH AA +G+ + Sbjct: 219 GQDLDWIDAQGATLLHIAGANGYLRAAELLLDHGVRVDVKDWDGWEPLHAAAFWGQMQMA 278 Query: 327 DLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 +LL+ HGA+++ + + PID+ ++E K+L Sbjct: 279 ELLVSHGASLSARTSMDEMPIDLC----EEEEFKVL 310 Score = 52.0 bits (123), Expect = 2e-06 Identities = 32/96 (33%), Positives = 47/96 (48%) Frame = -1 Query: 540 DGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLH 361 D E ++ L D + +G ALH C + ++LL GA V+A D TPLH Sbjct: 80 DAEEVRYFLKNKVSPDLCNEDGLTALHQCCIDNFEEIVKLLLSHGANVNAKDNELWTPLH 139 Query: 360 YAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAK 253 AA G V +L+++GA + N DG P D+ + Sbjct: 140 AAATCGHINLVKILVQYGADLLAVNSDGNMPYDLCE 175 Score = 40.0 bits (92), Expect = 0.006 Identities = 22/67 (32%), Positives = 34/67 (50%) Frame = -1 Query: 420 LLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQ 241 ++ AG +D +D T LH A G +LLL HG V +++ DG P+ A Q Sbjct: 215 MIAAGQDLDWIDAQGATLLHIAGANGYLRAAELLLDHGVRVDVKDWDGWEPLHAAAFWGQ 274 Query: 240 DEVLKLL 220 ++ +LL Sbjct: 275 MQMAELL 281 Score = 30.8 bits (68), Expect = 3.8 Identities = 27/88 (30%), Positives = 39/88 (44%), Gaps = 15/88 (17%) Frame = -1 Query: 438 FKCAEILLEAGAAVDAMD-----KNKNTP----------LHYAAGYGRKECVDLLLKHGA 304 F+ + LLEA DA + KNK +P LH +E V LLL HGA Sbjct: 66 FEASVALLEASLRNDAEEVRYFLKNKVSPDLCNEDGLTALHQCCIDNFEEIVKLLLSHGA 125 Query: 303 AVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 V ++ + TP+ A ++K+L Sbjct: 126 NVNAKDNELWTPLHAAATCGHINLVKIL 153
>MYPT2_HUMAN (O60237) Protein phosphatase 1 regulatory subunit 12B (Myosin| phosphatase-targeting subunit 2) (Myosin phosphatase target subunit 2) Length = 982 Score = 60.8 bits (146), Expect = 3e-09 Identities = 35/99 (35%), Positives = 52/99 (52%) Frame = -1 Query: 549 SVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNT 370 S GD + ++K L GAD + + +G ALH AC + L+E A V+ D T Sbjct: 67 SSGDTDEVRKLLARGADINTVNVDGLTALHQACIDENLDMVKFLVENRANVNQQDNEGWT 126 Query: 369 PLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAK 253 PLH AA G + + HGA+V + N +G+ P D+A+ Sbjct: 127 PLHAAASCGYLNIAEYFINHGASVGIVNSEGEVPSDLAE 165 Score = 51.6 bits (122), Expect = 2e-06 Identities = 35/102 (34%), Positives = 54/102 (52%), Gaps = 1/102 (0%) Frame = -1 Query: 516 LDGGADKDEEDSE-GRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGR 340 L+ G +D + G ALH A G + +L++AG ++ D + TPLH AA +G Sbjct: 203 LNSGKIEDVRQARSGATALHVAAAKGYSEVLRLLIQAGYELNVQDYDGWTPLHAAAHWGV 262 Query: 339 KECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLLEK 214 KE +L + + ++N G+TP DVA E L+LL+K Sbjct: 263 KEACSILAEALCDMDIRNKLGQTPFDVAD-EGLVEHLELLQK 303
>ANKR2_MOUSE (Q9WV06) Ankyrin repeat domain-containing protein 2 (Skeletal| muscle ankyrin repeat protein) (mArpp) Length = 328 Score = 60.8 bits (146), Expect = 3e-09 Identities = 36/115 (31%), Positives = 58/115 (50%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMD 385 +H + G E L+K L+ GA D +D A+H+AC G + +L GA + D Sbjct: 154 LHRASLEGHMEILEKLLENGATVDFQDRLDCTAMHWACRGGHLEVVRLLQSRGADTNVRD 213 Query: 384 KNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 K +TPLH A G E V+ L G + ++ +G + + A N+ +++KLL Sbjct: 214 KLLSTPLHVAVRTGHVEIVEHFLSLGLDINAKDREGDSALHDAVRLNRYKIIKLL 268 Score = 50.8 bits (120), Expect = 4e-06 Identities = 35/101 (34%), Positives = 47/101 (46%) Frame = -1 Query: 528 LKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAG 349 + K L G D D R ALH A G + E LLE GA VD D+ T +H+A Sbjct: 133 IDKYLADGGSADTCDEFRRTALHRASLEGHMEILEKLLENGATVDFQDRLDCTAMHWACR 192 Query: 348 YGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLK 226 G E V LL GA +++ TP+ VA E+++ Sbjct: 193 GGHLEVVRLLQSRGADTNVRDKLLSTPLHVAVRTGHVEIVE 233
>HTK16_HYDAT (P53356) Tyrosine-protein kinase HTK16 (EC 2.7.10.2)| Length = 757 Score = 60.8 bits (146), Expect = 3e-09 Identities = 36/106 (33%), Positives = 56/106 (52%), Gaps = 3/106 (2%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMD 385 +H + S GD + + L+ GAD D+ GR + C Y +L+ G+A D + Sbjct: 156 LHISCSNGDNDIVAMLLNAGADASAIDANGRTPVQVVCFYNHASTLHLLISKGSA-DFLK 214 Query: 384 KNKNT---PLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVA 256 ++ N PLH AA G ECV +LL A++ +++DG TP D+A Sbjct: 215 RSPNNGWVPLHEAAMRGSLECVKVLLSFNASMYPRSLDGDTPRDLA 260 Score = 47.0 bits (110), Expect = 5e-05 Identities = 28/88 (31%), Positives = 42/88 (47%), Gaps = 2/88 (2%) Frame = -1 Query: 477 GRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLLKHGAAV 298 G ALH +C G+ +LL AGA A+D N TP+ Y + LL+ G+A Sbjct: 152 GLTALHISCSNGDNDIVAMLLNAGADASAIDANGRTPVQVVCFYNHASTLHLLISKGSAD 211 Query: 297 TLQNM--DGKTPIDVAKLNNQDEVLKLL 220 L+ +G P+ A + E +K+L Sbjct: 212 FLKRSPNNGWVPLHEAAMRGSLECVKVL 239
>DAPK1_HUMAN (P53355) Death-associated protein kinase 1 (EC 2.7.11.1) (DAP| kinase 1) Length = 1432 Score = 60.1 bits (144), Expect = 6e-09 Identities = 38/107 (35%), Positives = 48/107 (44%) Frame = -1 Query: 534 EGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYA 355 E +K L G D +D G LH AC G L EA +D +K TPLH A Sbjct: 560 EVIKTLLSQGCFVDYQDRHGNTPLHVACKDGNMPIVVALCEANCNLDISNKYGRTPLHLA 619 Query: 354 AGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLLEK 214 A G + V L GA+V DGKT D+A+ + V LL + Sbjct: 620 ANNGILDVVRYLCLMGASVEALTTDGKTAEDLARSEQHEHVAGLLAR 666 Score = 57.4 bits (137), Expect = 4e-08 Identities = 35/117 (29%), Positives = 55/117 (47%), Gaps = 2/117 (1%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEI--LLEAGAAVDA 391 V+ A G + LK + D +D G ALH A YG A++ L G+ + Sbjct: 416 VYWAARHGHVDTLKFLSENKCPLDVKDKSGEMALHVAARYGHADVAQVQVLCSFGSNPNI 475 Query: 390 MDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 DK + TPLH AA +G L + G V ++N +G+TP+ A ++++ L Sbjct: 476 QDKEEETPLHCAAWHGYYSVAKALCEAGCNVNIKNREGETPLLTASARGYHDIVECL 532 Score = 53.9 bits (128), Expect = 4e-07 Identities = 32/96 (33%), Positives = 48/96 (50%) Frame = -1 Query: 507 GADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECV 328 GAD + D +G ALH A + + + LL G VD D++ NTPLH A G V Sbjct: 536 GADLNACDKDGHIALHLAVRRCQMEVIKTLLSQGCFVDYQDRHGNTPLHVACKDGNMPIV 595 Query: 327 DLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 L + + + N G+TP+ +A N +V++ L Sbjct: 596 VALCEANCNLDISNKYGRTPLHLAANNGILDVVRYL 631 Score = 53.5 bits (127), Expect = 5e-07 Identities = 31/96 (32%), Positives = 50/96 (52%) Frame = -1 Query: 507 GADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECV 328 G++ + +D E LH A +G + A+ L EAG V+ ++ TPL A+ G + V Sbjct: 470 GSNPNIQDKEEETPLHCAAWHGYYSVAKALCEAGCNVNIKNREGETPLLTASARGYHDIV 529 Query: 327 DLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 + L +HGA + + DG + +A Q EV+K L Sbjct: 530 ECLAEHGADLNACDKDGHIALHLAVRRCQMEVIKTL 565 Score = 48.1 bits (113), Expect = 2e-05 Identities = 36/113 (31%), Positives = 53/113 (46%), Gaps = 1/113 (0%) Frame = -1 Query: 525 KKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGY 346 K + G + + ++ EG L A G E L E GA ++A DK+ + LH A Sbjct: 497 KALCEAGCNVNIKNREGETPLLTASARGYHDIVECLAEHGADLNACDKDGHIALHLAVRR 556 Query: 345 GRKECVDLLLKHGAAVTLQNMDGKTPIDVA-KLNNQDEVLKLLEKDVFL*IAS 190 + E + LL G V Q+ G TP+ VA K N V+ L E + L I++ Sbjct: 557 CQMEVIKTLLSQGCFVDYQDRHGNTPLHVACKDGNMPIVVALCEANCNLDISN 609 Score = 46.6 bits (109), Expect = 7e-05 Identities = 31/113 (27%), Positives = 53/113 (46%), Gaps = 2/113 (1%) Frame = -1 Query: 552 ASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKN 373 A G+ + L+ + G+ D +D G A+++A +G + L E +D DK+ Sbjct: 387 AGCGNIQILQLLIKRGSRIDVQDKGGSNAVYWAARHGHVDTLKFLSENKCPLDVKDKSGE 446 Query: 372 TPLHYAAGYGRKEC--VDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 LH AA YG + V +L G+ +Q+ + +TP+ A + V K L Sbjct: 447 MALHVAARYGHADVAQVQVLCSFGSNPNIQDKEEETPLHCAAWHGYYSVAKAL 499
>INVS_HUMAN (Q9Y283) Inversin (Inversion of embryo turning homolog)| (Nephrocystin-2) Length = 1065 Score = 60.1 bits (144), Expect = 6e-09 Identities = 38/111 (34%), Positives = 59/111 (53%), Gaps = 2/111 (1%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLE--AGAAVDA 391 +H A G+ +K L A+ ++D E LH + KC +LL+ A VD Sbjct: 85 LHLAAQKGNYRFMKLLLTRRANWMQKDLEEMTPLHLTTRHRSPKCLALLLKFMAPGEVDT 144 Query: 390 MDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQD 238 DKNK T LH++A Y E V LL+KH + + + +++GK P+ A N++D Sbjct: 145 QDKNKQTALHWSAYYNNPEHVKLLIKHDSNIGIPDVEGKIPLHWA-ANHKD 194 Score = 58.5 bits (140), Expect = 2e-08 Identities = 36/100 (36%), Positives = 50/100 (50%) Frame = -1 Query: 519 ALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGR 340 +L D + D G ALH A G ++LLE A VDA D K+TPL A G Sbjct: 343 SLKSDIDINMADKYGGTALHAAALSGHVSTVKLLLENNAQVDATDVMKHTPLFRACEMGH 402 Query: 339 KECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 K+ + L+K GA V L + DG + + A L +V ++L Sbjct: 403 KDVIQTLIKGGARVDLVDQDGHSLLHWAALGGNADVCQIL 442 Score = 58.5 bits (140), Expect = 2e-08 Identities = 41/120 (34%), Positives = 60/120 (50%), Gaps = 1/120 (0%) Frame = -1 Query: 570 SIVHHTASVGDGEGLKKALDGG-ADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVD 394 S VH A GD L++ + G A KD+ED GR L + CA+ LL+AGA V+ Sbjct: 16 SQVHAAAVNGDKGALQRLIVGNSALKDKEDQFGRTPLMYCVLADRLDCADALLKAGADVN 75 Query: 393 AMDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLLEK 214 D ++ T LH AA G + LLL A ++++ TP+ + + + L LL K Sbjct: 76 KTDHSQRTALHLAAQKGNYRFMKLLLTRRANWMQKDLEEMTPLHLTTRHRSPKCLALLLK 135 Score = 51.6 bits (122), Expect = 2e-06 Identities = 35/130 (26%), Positives = 61/130 (46%), Gaps = 2/130 (1%) Frame = -1 Query: 570 SIVHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDA 391 S++H A G+ + + ++ + + +D GR L A G C +L+E A + Sbjct: 425 SLLHWAALGGNADVCQILIENKINPNVQDYAGRTPLQCAAYGGYINCMAVLMENNADPNI 484 Query: 390 MDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTL--QNMDGKTPIDVAKLNNQDEVLKLLE 217 DK T LH++ G + + LLL A N + TP+D A L + EV++ + Sbjct: 485 QDKEGRTALHWSCNNGYLDAIKLLLDFAAFPNQMENNEERYTPLDYALLGERHEVIQFML 544 Query: 216 KDVFL*IASL 187 + L IA++ Sbjct: 545 EHGALSIAAI 554 Score = 49.7 bits (117), Expect = 8e-06 Identities = 31/109 (28%), Positives = 54/109 (49%) Frame = -1 Query: 546 VGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTP 367 +G + ++ + GGA D D +G LH+A G +IL+E + D TP Sbjct: 400 MGHKDVIQTLIKGGARVDLVDQDGHSLLHWAALGGNADVCQILIENKINPNVQDYAGRTP 459 Query: 366 LHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 L AA G C+ +L+++ A +Q+ +G+T + + N + +KLL Sbjct: 460 LQCAAYGGYINCMAVLMENNADPNIQDKEGRTALHWSCNNGYLDAIKLL 508 Score = 48.5 bits (114), Expect = 2e-05 Identities = 29/103 (28%), Positives = 50/103 (48%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMD 385 +H A G +K L+ A D D L AC G + L++ GA VD +D Sbjct: 361 LHAAALSGHVSTVKLLLENNAQVDATDVMKHTPLFRACEMGHKDVIQTLIKGGARVDLVD 420 Query: 384 KNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVA 256 ++ ++ LH+AA G + +L+++ +Q+ G+TP+ A Sbjct: 421 QDGHSLLHWAALGGNADVCQILIENKINPNVQDYAGRTPLQCA 463 Score = 48.1 bits (113), Expect = 2e-05 Identities = 31/94 (32%), Positives = 47/94 (50%), Gaps = 2/94 (2%) Frame = -1 Query: 489 EDSEGRRALHFACGYGEFKCAEILLEAGAA-VDAMDKNKNTPLHYAAGYGRKECVDLLLK 313 +D EGR LHFA G ++L + + + D TPLH+AA G + V LLL+ Sbjct: 217 QDYEGRTPLHFAVADGNVTVVDVLTSYESCNITSYDNLFRTPLHWAALLGHAQIVHLLLE 276 Query: 312 HGAAVTL-QNMDGKTPIDVAKLNNQDEVLKLLEK 214 + T+ + G TP+ A +N E +K+ K Sbjct: 277 RNKSGTIPSDSQGATPLHYAAQSNFAETVKVFLK 310 Score = 46.2 bits (108), Expect = 9e-05 Identities = 39/147 (26%), Positives = 63/147 (42%), Gaps = 3/147 (2%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDA-- 391 +H+ A E +K L + KD+ D EGR + +A G G +L + +D Sbjct: 293 LHYAAQSNFAETVKVFLKHPSVKDDSDLEGRTSFMWAAGKGSDDVLRTMLSLKSDIDINM 352 Query: 390 MDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPI-DVAKLNNQDEVLKLLEK 214 DK T LH AA G V LLL++ A V ++ TP+ ++ ++D + L++ Sbjct: 353 ADKYGGTALHAAALSGHVSTVKLLLENNAQVDATDVMKHTPLFRACEMGHKDVIQTLIKG 412 Query: 213 DVFL*IASLGSHEETWPSSCFTSLWHW 133 + + H SL HW Sbjct: 413 GARVDLVDQDGH----------SLLHW 429 Score = 42.0 bits (97), Expect = 0.002 Identities = 28/90 (31%), Positives = 42/90 (46%), Gaps = 1/90 (1%) Frame = -1 Query: 486 DSEGRRALHFACGYGEFKCAEILLEAG-AAVDAMDKNKNTPLHYAAGYGRKECVDLLLKH 310 D+ R LH+A G + +LLE + D TPLHYAA E V + LKH Sbjct: 252 DNLFRTPLHWAALLGHAQIVHLLLERNKSGTIPSDSQGATPLHYAAQSNFAETVKVFLKH 311 Query: 309 GAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 + +++G+T A D+VL+ + Sbjct: 312 PSVKDDSDLEGRTSFMWAAGKGSDDVLRTM 341 Score = 33.9 bits (76), Expect = 0.45 Identities = 24/91 (26%), Positives = 40/91 (43%), Gaps = 2/91 (2%) Frame = -1 Query: 486 DSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVD--LLLK 313 DS+G LH+A + ++ L+ + D D T +AAG G + + L LK Sbjct: 286 DSQGATPLHYAAQSNFAETVKVFLKHPSVKDDSDLEGRTSFMWAAGKGSDDVLRTMLSLK 345 Query: 312 HGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 + + + G T + A L+ +KLL Sbjct: 346 SDIDINMADKYGGTALHAAALSGHVSTVKLL 376
>SHAN3_RAT (Q9JLU4) SH3 and multiple ankyrin repeat domains 3 (Shank3)| (Proline-rich synapse associated protein 2) (ProSAP2) (SPANK-2) Length = 1815 Score = 60.1 bits (144), Expect = 6e-09 Identities = 38/116 (32%), Positives = 56/116 (48%), Gaps = 1/116 (0%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRAL-HFACGYGEFKCAEILLEAGAAVDAM 388 VH + L LD GA D +DS G L H A G G+ C E+LL A + Sbjct: 262 VHCATRQRNAGALTTLLDLGASPDYKDSRGLTPLYHSALGGGDALCCELLLHDHAQLGTT 321 Query: 387 DKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 D+N +H A +G + ++ LL +GA + QN G T + + L NQ+ ++L Sbjct: 322 DENGWQEIHQACRFGHVQHLEHLLFYGANMGAQNASGNTALHICALYNQESCARVL 377 Score = 43.1 bits (100), Expect = 7e-04 Identities = 24/85 (28%), Positives = 37/85 (43%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMD 385 +H G + L+ L GA+ +++ G ALH Y + CA +LL GA D + Sbjct: 329 IHQACRFGHVQHLEHLLFYGANMGAQNASGNTALHICALYNQESCARVLLFRGANKDVRN 388 Query: 384 KNKNTPLHYAAGYGRKECVDLLLKH 310 N T A G E +++ H Sbjct: 389 YNSQTAFQVAIIAGNFELAEVIKTH 413
>ASB16_MOUSE (Q8VHS5) Ankyrin repeat and SOCS box protein 16 (ASB-16)| Length = 453 Score = 60.1 bits (144), Expect = 6e-09 Identities = 35/104 (33%), Positives = 57/104 (54%), Gaps = 1/104 (0%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVD-AM 388 +H + + ++ L GA + EG LH +CA++LLEAGA+V+ A Sbjct: 147 LHEACAQAHPDCVRLLLTFGAKANVSSEEGMTPLHLCTSPESLQCAKLLLEAGASVNVAS 206 Query: 387 DKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVA 256 +++ TPLH AA G ++ V L L++GA V L+ G+T ++ A Sbjct: 207 QESEVTPLHVAAARGLEQHVALYLQNGADVALRTSQGETALNAA 250 Score = 58.5 bits (140), Expect = 2e-08 Identities = 42/117 (35%), Positives = 56/117 (47%), Gaps = 8/117 (6%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFK--------CAEILLEA 409 +H A+ G + + L GAD S+G AL+ AC E A LLEA Sbjct: 214 LHVAAARGLEQHVALYLQNGADVALRTSQGETALNAACAGAEGPGSSRQHEAAARQLLEA 273 Query: 408 GAAVDAMDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQD 238 GA A + ++TPLH A G +LLL+HGA+ + N G TP+D A QD Sbjct: 274 GADPQAAGRKRHTPLHNACANGCGGLAELLLRHGASPGVTNGAGHTPMDCALQAVQD 330 Score = 49.7 bits (117), Expect = 8e-06 Identities = 28/86 (32%), Positives = 42/86 (48%), Gaps = 1/86 (1%) Frame = -1 Query: 477 GRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLLKHGAAV 298 GR ALH AC C +LL GA + + TPLH +C LLL+ GA+V Sbjct: 143 GRAALHEACAQAHPDCVRLLLTFGAKANVSSEEGMTPLHLCTSPESLQCAKLLLEAGASV 202 Query: 297 TLQNMDGK-TPIDVAKLNNQDEVLKL 223 + + + + TP+ VA ++ + L Sbjct: 203 NVASQESEVTPLHVAAARGLEQHVAL 228 Score = 38.5 bits (88), Expect = 0.018 Identities = 26/82 (31%), Positives = 36/82 (43%) Frame = -1 Query: 465 LHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQN 286 L A G CA L+ GA +DA + LH A +CV LLL GA + + Sbjct: 115 LTIAVARGYTDCARHLILQGAELDARIGGR-AALHEACAQAHPDCVRLLLTFGAKANVSS 173 Query: 285 MDGKTPIDVAKLNNQDEVLKLL 220 +G TP+ + + KLL Sbjct: 174 EEGMTPLHLCTSPESLQCAKLL 195
>ACBD6_BRARE (Q4V8X4) Acyl-CoA-binding domain-containing protein 6| Length = 300 Score = 60.1 bits (144), Expect = 6e-09 Identities = 34/104 (32%), Positives = 55/104 (52%), Gaps = 1/104 (0%) Frame = -1 Query: 534 EGLKKALDGGA-DKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHY 358 E + KA+ D + D EGR LH+AC G +LL+ A +++ D T LHY Sbjct: 190 EHVSKAISSKTVDVNTRDEEGRALLHWACDRGHKDLVSLLLQNNADINSQDDEGQTALHY 249 Query: 357 AAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLK 226 A+ E V+LLLK GA ++++ +G P +V + + +L+ Sbjct: 250 ASACEFAEIVELLLKAGADPSIKDQEGSLPEEVTESSAISSLLR 293 Score = 37.7 bits (86), Expect = 0.031 Identities = 20/68 (29%), Positives = 34/68 (50%) Frame = -1 Query: 570 SIVHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDA 391 +++H G + + L AD + +D EG+ ALH+A + E+LL+AGA Sbjct: 212 ALLHWACDRGHKDLVSLLLQNNADINSQDDEGQTALHYASACEFAEIVELLLKAGADPSI 271 Query: 390 MDKNKNTP 367 D+ + P Sbjct: 272 KDQEGSLP 279 Score = 37.4 bits (85), Expect = 0.041 Identities = 20/62 (32%), Positives = 34/62 (54%) Frame = -1 Query: 399 VDAMDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 V+ D+ LH+A G K+ V LLL++ A + Q+ +G+T + A E+++LL Sbjct: 203 VNTRDEEGRALLHWACDRGHKDLVSLLLQNNADINSQDDEGQTALHYASACEFAEIVELL 262 Query: 219 EK 214 K Sbjct: 263 LK 264
>CDN2C_HUMAN (P42773) Cyclin-dependent kinase 6 inhibitor (p18-INK6)| (Cyclin-dependent kinase 4 inhibitor C) (p18-INK4c) Length = 168 Score = 59.7 bits (143), Expect = 8e-09 Identities = 39/111 (35%), Positives = 59/111 (53%), Gaps = 1/111 (0%) Frame = -1 Query: 546 VGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTP 367 +G+ E ++ L GA+ D +D G +H A G + LLE A V+ D N P Sbjct: 47 LGNPEIARRLLLRGANPDLKDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLP 106 Query: 366 LHYAAGYGRKECVDLLLKHGAA-VTLQNMDGKTPIDVAKLNNQDEVLKLLE 217 LH AA G V+ L+KH A+ V +N G T D+A+L ++EV+ L++ Sbjct: 107 LHLAAKEGHLRVVEFLVKHTASNVGHRNHKGDTACDLARLYGRNEVVSLMQ 157 Score = 44.7 bits (104), Expect = 3e-04 Identities = 29/90 (32%), Positives = 45/90 (50%), Gaps = 1/90 (1%) Frame = -1 Query: 570 SIVHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAA-VD 394 +++H A G + L+ L+ AD + ED+EG LH A G + E L++ A+ V Sbjct: 72 AVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVKHTASNVG 131 Query: 393 AMDKNKNTPLHYAAGYGRKECVDLLLKHGA 304 + +T A YGR E V L+ +GA Sbjct: 132 HRNHKGDTACDLARLYGRNEVVSLMQANGA 161
>PP16A_HUMAN (Q96I34) Protein phosphatase 1 regulatory subunit 16A (Myosin| phosphatase-targeting subunit 3) Length = 528 Score = 59.7 bits (143), Expect = 8e-09 Identities = 36/106 (33%), Positives = 58/106 (54%) Frame = -1 Query: 534 EGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYA 355 + ++ L GAD G LH A G + A +LLE A++ A D++ PLH A Sbjct: 213 DDIRSRLQAGADLHAPLDHGATLLHVAAANGFSEAAALLLEHRASLSAKDQDGWEPLHAA 272 Query: 354 AGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLLE 217 A +G+ V+LL+ HGA + +++ +TP+DV +++ KLLE Sbjct: 273 AYWGQVPLVELLVAHGADLNAKSLMDETPLDVC--GDEEVRAKLLE 316 Score = 59.7 bits (143), Expect = 8e-09 Identities = 40/117 (34%), Positives = 58/117 (49%) Frame = -1 Query: 567 IVHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAM 388 ++ A+ D E +++ L G D + +G ALH C + + LLEAGA ++A Sbjct: 74 VLLEAAARNDLEEVRQFLGSGVSPDLANEDGLTALHQCCIDDFREMVQQLLEAGANINAC 133 Query: 387 DKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLLE 217 D TPLH AA G V+LL+ GA + N DG P D L + ++ L LE Sbjct: 134 DSECWTPLHAAATCGHLHLVELLIASGANLLAVNTDGNMPYD---LCDDEQTLDCLE 187
>OSBL1_MOUSE (Q91XL9) Oxysterol-binding protein-related protein 1 (OSBP-related| protein 1) (ORP-1) Length = 950 Score = 59.7 bits (143), Expect = 8e-09 Identities = 44/127 (34%), Positives = 68/127 (53%), Gaps = 10/127 (7%) Frame = -1 Query: 567 IVHHTASVGDGEGLKKALDGGADKD---EEDSEGRRA-------LHFACGYGEFKCAEIL 418 ++HH + G+ E ++K L A + + D +GR LH AC +G + E L Sbjct: 9 LLHHARN-GNAEEVRKLLAAMARMEVVADIDCKGRSKSNLGWTPLHLACYFGHKQVVEDL 67 Query: 417 LEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQD 238 L+AGA V+ ++ +TPLH AA GRKE V LLL++ A T+ N G+T + + Sbjct: 68 LKAGAKVNMLNDMGDTPLHRAAFTGRKELVLLLLEYDADSTVVNGSGQT---AKEATHDK 124 Query: 237 EVLKLLE 217 E+ +LE Sbjct: 125 EIRNMLE 131 Score = 42.4 bits (98), Expect = 0.001 Identities = 21/49 (42%), Positives = 32/49 (65%) Frame = -1 Query: 399 VDAMDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAK 253 V+ D+ NTPLH AA K+CV LL+ GA +L+N + + P+D+A+ Sbjct: 169 VNCSDQLGNTPLHCAAYRAHKQCVLKLLRSGADPSLKNKNDQKPLDLAQ 217
>CT086_HUMAN (Q9BZ19) Hypothetical protein C20orf86| Length = 240 Score = 59.7 bits (143), Expect = 8e-09 Identities = 32/76 (42%), Positives = 47/76 (61%), Gaps = 1/76 (1%) Frame = -1 Query: 468 ALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQ 289 AL+ A G F + LLE GA+ + TPLH AA GR +C+ LLL+HGA++ + Sbjct: 118 ALYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQHGASIHDR 177 Query: 288 NMDGKTPIDVA-KLNN 244 + G+TPI +A +LN+ Sbjct: 178 DAKGETPISIAHRLNH 193 Score = 30.8 bits (68), Expect = 3.8 Identities = 16/49 (32%), Positives = 28/49 (57%) Frame = -1 Query: 366 LHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 L+ A+ G + V LL+HGA+ ++ G+TP+ VA + + + LL Sbjct: 119 LYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILL 167
>ANKS1_HUMAN (Q92625) Ankyrin repeat and SAM domain-containing protein 1A (Odin)| Length = 1133 Score = 59.7 bits (143), Expect = 8e-09 Identities = 38/118 (32%), Positives = 62/118 (52%), Gaps = 3/118 (2%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAA---VD 394 +HH A G + ++ L A + DS+G LH A G+ + +L+ G + V+ Sbjct: 83 LHHAALNGHKDVVEVLLRNDALTNVADSKGCYPLHLAAWKGDAQIVRLLIHQGPSHTRVN 142 Query: 393 AMDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 + + T LH AA YG E V +LL+ T++N +TP+D+A L + EV+K+L Sbjct: 143 EQNNDNETALHCAAQYGHTEVVKVLLEELTDPTMRNNKFETPLDLAALYGRLEVVKML 200 Score = 48.9 bits (115), Expect = 1e-05 Identities = 34/118 (28%), Positives = 55/118 (46%), Gaps = 3/118 (2%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADK---DEEDSEGRRALHFACGYGEFKCAEILLEAGAAVD 394 +H A GD + ++ + G +E++++ ALH A YG + ++LLE Sbjct: 116 LHLAAWKGDAQIVRLLIHQGPSHTRVNEQNNDNETALHCAAQYGHTEVVKVLLEELTDPT 175 Query: 393 AMDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 + TPL AA YGR E V +LL + N TP+ +A N V+++L Sbjct: 176 MRNNKFETPLDLAALYGRLEVVKMLLNAHPNLLSCNTKKHTPLHLAARNGHKAVVQVL 233 Score = 45.1 bits (105), Expect = 2e-04 Identities = 34/115 (29%), Positives = 49/115 (42%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMD 385 +H A G E +K L+ D +++ L A YG + ++LL A + + + Sbjct: 152 LHCAAQYGHTEVVKVLLEELTDPTMRNNKFETPLDLAALYGRLEVVKMLLNAHPNLLSCN 211 Query: 384 KNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 K+TPLH AA G K V +LL G Q G + A D V LL Sbjct: 212 TKKHTPLHLAARNGHKAVVQVLLDAGMDSNYQTEMGSALHEAALFGKTDVVQILL 266 Score = 45.1 bits (105), Expect = 2e-04 Identities = 32/96 (33%), Positives = 44/96 (45%), Gaps = 3/96 (3%) Frame = -1 Query: 486 DSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLLKHG 307 DS G LH A G E+LL A + D PLH AA G + V LL+ G Sbjct: 76 DSTGYTPLHHAALNGHKDVVEVLLRNDALTNVADSKGCYPLHLAAWKGDAQIVRLLIHQG 135 Query: 306 AA---VTLQNMDGKTPIDVAKLNNQDEVLKLLEKDV 208 + V QN D +T + A EV+K+L +++ Sbjct: 136 PSHTRVNEQNNDNETALHCAAQYGHTEVVKVLLEEL 171 Score = 41.2 bits (95), Expect = 0.003 Identities = 20/63 (31%), Positives = 36/63 (57%) Frame = -1 Query: 408 GAAVDAMDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVL 229 G V+ +D TPLH+AA G K+ V++LL++ A + + G P+ +A +++ Sbjct: 69 GPNVNCVDSTGYTPLHHAALNGHKDVVEVLLRNDALTNVADSKGCYPLHLAAWKGDAQIV 128 Query: 228 KLL 220 +LL Sbjct: 129 RLL 131 Score = 31.2 bits (69), Expect = 2.9 Identities = 22/67 (32%), Positives = 32/67 (47%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMD 385 +H A G ++ LD G D + + G ALH A +G+ +ILL AG V+ D Sbjct: 218 LHLAARNGHKAVVQVLLDAGMDSNYQTEMGS-ALHEAALFGKTDVVQILLAAGTDVNIKD 276 Query: 384 KNKNTPL 364 + T L Sbjct: 277 NHGLTAL 283
>MTPN_RAT (P62775) Myotrophin (V-1 protein) (Granule cell differentiation| protein) Length = 117 Score = 59.7 bits (143), Expect = 8e-09 Identities = 35/94 (37%), Positives = 50/94 (53%) Frame = -1 Query: 543 GDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPL 364 GD + +K + G D + GR+ LH+A G+ + E LL GA ++A DK+ TPL Sbjct: 12 GDLDEVKDYVAKGEDVNRTLEGGRKPLHYAADCGQLEILEFLLLKGADINAPDKHHITPL 71 Query: 363 HYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPID 262 A G CV LLL GA T++ DG T ++ Sbjct: 72 LSAVYEGHVSCVKLLLSKGADKTVKGPDGLTALE 105 Score = 31.6 bits (70), Expect = 2.2 Identities = 18/50 (36%), Positives = 25/50 (50%) Frame = -1 Query: 369 PLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 PLHYAA G+ E ++ LL GA + + TP+ A +KLL Sbjct: 37 PLHYAADCGQLEILEFLLLKGADINAPDKHHITPLLSAVYEGHVSCVKLL 86
>MTPN_MOUSE (P62774) Myotrophin (V-1 protein) (Granule cell differentiation| protein) Length = 117 Score = 59.7 bits (143), Expect = 8e-09 Identities = 35/94 (37%), Positives = 50/94 (53%) Frame = -1 Query: 543 GDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPL 364 GD + +K + G D + GR+ LH+A G+ + E LL GA ++A DK+ TPL Sbjct: 12 GDLDEVKDYVAKGEDVNRTLEGGRKPLHYAADCGQLEILEFLLLKGADINAPDKHHITPL 71 Query: 363 HYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPID 262 A G CV LLL GA T++ DG T ++ Sbjct: 72 LSAVYEGHVSCVKLLLSKGADKTVKGPDGLTALE 105 Score = 31.6 bits (70), Expect = 2.2 Identities = 18/50 (36%), Positives = 25/50 (50%) Frame = -1 Query: 369 PLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 PLHYAA G+ E ++ LL GA + + TP+ A +KLL Sbjct: 37 PLHYAADCGQLEILEFLLLKGADINAPDKHHITPLLSAVYEGHVSCVKLL 86
>DAPK1_MOUSE (Q80YE7) Death-associated protein kinase 1 (EC 2.7.11.1) (DAP| kinase 1) Length = 1442 Score = 59.7 bits (143), Expect = 8e-09 Identities = 33/108 (30%), Positives = 51/108 (47%) Frame = -1 Query: 543 GDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPL 364 G + LK + D +D G ALH A YG ++L G+ D DK + TPL Sbjct: 423 GHVDTLKFLNENKCPLDVKDKSGETALHVAARYGHADVVQLLCSFGSNPDFQDKEEETPL 482 Query: 363 HYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 H AA +G L + G V ++N +G+TP+ A ++++ L Sbjct: 483 HCAAWHGYYSVAKALCEVGCNVNIKNREGETPLLTASARGYHDIVECL 530 Score = 59.3 bits (142), Expect = 1e-08 Identities = 39/107 (36%), Positives = 48/107 (44%) Frame = -1 Query: 534 EGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYA 355 E +K L G+ D +D G LH AC G L EA +D +K TPLH A Sbjct: 558 EVIKTLLGHGSFVDFQDRHGNTPLHVACKDGSAPIVVALCEASCNLDISNKYGRTPLHLA 617 Query: 354 AGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLLEK 214 A G + V L GA V DGKT D+AK + V LL + Sbjct: 618 ANNGILDVVRYLCLMGANVEALTSDGKTAEDLAKAEQHEHVAGLLAR 664 Score = 57.8 bits (138), Expect = 3e-08 Identities = 34/115 (29%), Positives = 56/115 (48%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMD 385 +H A G + ++ G++ D +D E LH A +G + A+ L E G V+ + Sbjct: 449 LHVAARYGHADVVQLLCSFGSNPDFQDKEEETPLHCAAWHGYYSVAKALCEVGCNVNIKN 508 Query: 384 KNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 + TPL A+ G + V+ L +HGA + + DG + +A Q EV+K L Sbjct: 509 REGETPLLTASARGYHDIVECLAEHGADLNASDKDGHIALHLAVRRCQMEVIKTL 563 Score = 54.3 bits (129), Expect = 3e-07 Identities = 32/96 (33%), Positives = 49/96 (51%) Frame = -1 Query: 507 GADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECV 328 GAD + D +G ALH A + + + LL G+ VD D++ NTPLH A G V Sbjct: 534 GADLNASDKDGHIALHLAVRRCQMEVIKTLLGHGSFVDFQDRHGNTPLHVACKDGSAPIV 593 Query: 327 DLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 L + + + N G+TP+ +A N +V++ L Sbjct: 594 VALCEASCNLDISNKYGRTPLHLAANNGILDVVRYL 629 Score = 53.9 bits (128), Expect = 4e-07 Identities = 33/111 (29%), Positives = 53/111 (47%) Frame = -1 Query: 552 ASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKN 373 A G+ + L+ + G+ D +D G A+++A +G + L E +D DK+ Sbjct: 387 AGCGNIQMLQLLIKRGSRIDVQDKGGSNAIYWASRHGHVDTLKFLNENKCPLDVKDKSGE 446 Query: 372 TPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 T LH AA YG + V LL G+ Q+ + +TP+ A + V K L Sbjct: 447 TALHVAARYGHADVVQLLCSFGSNPDFQDKEEETPLHCAAWHGYYSVAKAL 497 Score = 48.1 bits (113), Expect = 2e-05 Identities = 30/90 (33%), Positives = 44/90 (48%) Frame = -1 Query: 525 KKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGY 346 K + G + + ++ EG L A G E L E GA ++A DK+ + LH A Sbjct: 495 KALCEVGCNVNIKNREGETPLLTASARGYHDIVECLAEHGADLNASDKDGHIALHLAVRR 554 Query: 345 GRKECVDLLLKHGAAVTLQNMDGKTPIDVA 256 + E + LL HG+ V Q+ G TP+ VA Sbjct: 555 CQMEVIKTLLGHGSFVDFQDRHGNTPLHVA 584
>MTPN_CHICK (Q91955) Myotrophin (V-1 protein) (Granule cell differentiation| protein) Length = 118 Score = 59.3 bits (142), Expect = 1e-08 Identities = 35/94 (37%), Positives = 49/94 (52%) Frame = -1 Query: 543 GDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPL 364 GD + +K + G D + GR+ LH+A G+ + E LL GA ++A DK+ TPL Sbjct: 13 GDLDEVKDYVAKGEDVNRTLEGGRKPLHYAADCGQLEILEFLLLKGADINAPDKHNITPL 72 Query: 363 HYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPID 262 A G CV LLL GA T++ DG T + Sbjct: 73 LSAVYEGHVSCVKLLLSKGADKTVKGPDGLTAFE 106 Score = 32.3 bits (72), Expect = 1.3 Identities = 18/50 (36%), Positives = 25/50 (50%) Frame = -1 Query: 369 PLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 PLHYAA G+ E ++ LL GA + + TP+ A +KLL Sbjct: 38 PLHYAADCGQLEILEFLLLKGADINAPDKHNITPLLSAVYEGHVSCVKLL 87
>TRPA1_MOUSE (Q8BLA8) Transient receptor potential cation channel subfamily A| member 1 (Ankyrin-like with transmembrane domains protein 1) Length = 1125 Score = 59.3 bits (142), Expect = 1e-08 Identities = 34/96 (35%), Positives = 52/96 (54%), Gaps = 3/96 (3%) Frame = -1 Query: 492 EEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLLK 313 +ED++G LH+AC G LL ++ + K+K +PLH+AA YGR LL+ Sbjct: 409 DEDNDGCTPLHYACRQGVPVSVNNLLGFNVSIHSKSKDKKSPLHFAASYGRINTCQRLLQ 468 Query: 312 HGAAVTLQN---MDGKTPIDVAKLNNQDEVLKLLEK 214 + L N + G TP+ +A N D+V++LL K Sbjct: 469 DISDTRLLNEGDLHGMTPLHLAAKNGHDKVVQLLLK 504 Score = 51.2 bits (121), Expect = 3e-06 Identities = 32/121 (26%), Positives = 60/121 (49%), Gaps = 4/121 (3%) Frame = -1 Query: 570 SIVHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLE----AGA 403 S +H GD + +K LD GA D ++ ALHFA G ++++ + Sbjct: 242 SPLHLAVQSGDLDMIKMCLDNGAHIDMMENAKCMALHFAATQGATDIVKLMISSYTGSSD 301 Query: 402 AVDAMDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKL 223 V+A+D N+ T LH A+ + + + L+ GA + + +G++P+ +A + ++ L Sbjct: 302 IVNAVDGNQETLLHRASLFDHHDLAEYLISVGADINSTDSEGRSPLILATASASWNIVNL 361 Query: 222 L 220 L Sbjct: 362 L 362 Score = 43.1 bits (100), Expect = 7e-04 Identities = 31/118 (26%), Positives = 52/118 (44%), Gaps = 3/118 (2%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAM- 388 +H+ G + L + + + LHFA YG + LL+ + + Sbjct: 418 LHYACRQGVPVSVNNLLGFNVSIHSKSKDKKSPLHFAASYGRINTCQRLLQDISDTRLLN 477 Query: 387 --DKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 D + TPLH AA G + V LLLK G A+ L + +G T + A + + +K++ Sbjct: 478 EGDLHGMTPLHLAAKNGHDKVVQLLLKKG-ALFLSDHNGWTALHHASMGGYTQTMKVI 534 Score = 42.0 bits (97), Expect = 0.002 Identities = 22/61 (36%), Positives = 33/61 (54%) Frame = -1 Query: 489 EDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLLKH 310 E G AL C + +ILLE GA + +K + P+H AA G K+C++L+L + Sbjct: 162 EGENGNTALMSTCAKDNSEALQILLEKGAKLCKSNKWGDYPVHQAAFSGAKKCMELILAY 221 Query: 309 G 307 G Sbjct: 222 G 222 Score = 37.7 bits (86), Expect = 0.031 Identities = 40/156 (25%), Positives = 59/156 (37%), Gaps = 39/156 (25%) Frame = -1 Query: 558 HTASVGDGEGLKKALDG-GADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVD---- 394 H AS+ D L + L GAD + DSEGR L A + +LL GA VD Sbjct: 315 HRASLFDHHDLAEYLISVGADINSTDSEGRSPLILATASASWNIVNLLLCKGAKVDIKDH 374 Query: 393 --------------------------------AMDKNKN--TPLHYAAGYGRKECVDLLL 316 MD++ + TPLHYA G V+ LL Sbjct: 375 LGRNFLHLTVQQPYGLRNLRPEFMQMQHIKELVMDEDNDGCTPLHYACRQGVPVSVNNLL 434 Query: 315 KHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLLEKDV 208 ++ ++ D K+P+ A + + L +D+ Sbjct: 435 GFNVSIHSKSKDKKSPLHFAASYGRINTCQRLLQDI 470 Score = 36.2 bits (82), Expect = 0.091 Identities = 20/52 (38%), Positives = 29/52 (55%), Gaps = 2/52 (3%) Frame = -1 Query: 369 PLHYAAGYGRKECVDLLLKHGAAVTLQNMD--GKTPIDVAKLNNQDEVLKLL 220 PLH+AA G+ E ++L++ + L MD G TP+ A NQ E +K L Sbjct: 67 PLHHAAAEGQVELMELIINGSSCEVLNIMDGYGNTPLHCAAEKNQVESVKFL 118
>TRPA1_HUMAN (O75762) Transient receptor potential cation channel subfamily A| member 1 (Ankyrin-like with transmembrane domains protein 1) (Transformation sensitive-protein p120) Length = 1119 Score = 59.3 bits (142), Expect = 1e-08 Identities = 34/96 (35%), Positives = 52/96 (54%), Gaps = 3/96 (3%) Frame = -1 Query: 492 EEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLLK 313 +ED++G LH+AC G LL ++ + K+K +PLH+AA YGR LL+ Sbjct: 408 DEDNDGCTPLHYACRQGGPGSVNNLLGFNVSIHSKSKDKKSPLHFAASYGRINTCQRLLQ 467 Query: 312 HGAAVTLQN---MDGKTPIDVAKLNNQDEVLKLLEK 214 + L N + G TP+ +A N D+V++LL K Sbjct: 468 DISDTRLLNEGDLHGMTPLHLAAKNGHDKVVQLLLK 503 Score = 47.8 bits (112), Expect = 3e-05 Identities = 31/119 (26%), Positives = 56/119 (47%), Gaps = 4/119 (3%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAA----V 397 +H GD E +K LD GA D + A+HFA G + ++++ + + V Sbjct: 243 LHLAVQNGDLEMIKMCLDNGAQIDPVEKGRCTAIHFAATQGATEIVKLMISSYSGSVDIV 302 Query: 396 DAMDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 + D T LH A+ + E D L+ GA + + +G++P+ +A + ++ LL Sbjct: 303 NTTDGCHETMLHRASLFDHHELADYLISVGADINKIDSEGRSPLILATASASWNIVNLL 361 Score = 45.1 bits (105), Expect = 2e-04 Identities = 33/118 (27%), Positives = 54/118 (45%), Gaps = 3/118 (2%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADK--DEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDA 391 +H+ A+ G E ++K + + E D G LH A + + + LL GA + Sbjct: 67 LHYAAAEGQIELMEKITRDSSLEVLHEMDDYGNTPLHCAVEKNQIESVKFLLSRGANPNL 126 Query: 390 MDKNKNTPLHYAAGYGRKECVDLLLKHGAA-VTLQNMDGKTPIDVAKLNNQDEVLKLL 220 + N PLH A E + +LL+H V L+ +G T + +A N E L++L Sbjct: 127 RNFNMMAPLHIAVQGMNNEVMKVLLEHRTIDVNLEGENGNTAVIIACTTNNSEALQIL 184 Score = 44.7 bits (104), Expect = 3e-04 Identities = 29/101 (28%), Positives = 46/101 (45%), Gaps = 8/101 (7%) Frame = -1 Query: 501 DKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDL 322 D + E G A+ AC + +ILL GA +K P+H AA G KEC+++ Sbjct: 157 DVNLEGENGNTAVIIACTTNNSEALQILLNKGAKPCKSNKWGCFPIHQAAFSGSKECMEI 216 Query: 321 LLKHGAA--------VTLQNMDGKTPIDVAKLNNQDEVLKL 223 +L+ G + N TP+ +A N E++K+ Sbjct: 217 ILRFGEEHGYSRQLHINFMNNGKATPLHLAVQNGDLEMIKM 257 Score = 43.9 bits (102), Expect = 4e-04 Identities = 29/87 (33%), Positives = 45/87 (51%), Gaps = 1/87 (1%) Frame = -1 Query: 486 DSEGRRALHFACGYGEFKCAEILLEAGA-AVDAMDKNKNTPLHYAAGYGRKECVDLLLKH 310 D G ALH A G + +++L+ D +D++ NT LH+AA G + V LLL H Sbjct: 511 DHNGWTALHHASMGGYTQTMKVILDTNLKCTDRLDEDGNTALHFAAREGHAKAVALLLSH 570 Query: 309 GAAVTLQNMDGKTPIDVAKLNNQDEVL 229 A + L N + + +A N + EV+ Sbjct: 571 NADIVL-NKQQASFLHLALHNKRKEVV 596 Score = 43.9 bits (102), Expect = 4e-04 Identities = 31/118 (26%), Positives = 52/118 (44%), Gaps = 3/118 (2%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAM- 388 +H+ G + L + + + LHFA YG + LL+ + + Sbjct: 417 LHYACRQGGPGSVNNLLGFNVSIHSKSKDKKSPLHFAASYGRINTCQRLLQDISDTRLLN 476 Query: 387 --DKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 D + TPLH AA G + V LLLK G A+ L + +G T + A + + +K++ Sbjct: 477 EGDLHGMTPLHLAAKNGHDKVVQLLLKKG-ALFLSDHNGWTALHHASMGGYTQTMKVI 533 Score = 38.1 bits (87), Expect = 0.024 Identities = 40/156 (25%), Positives = 59/156 (37%), Gaps = 39/156 (25%) Frame = -1 Query: 558 HTASVGDGEGLKKALDG-GADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVD---- 394 H AS+ D L L GAD ++ DSEGR L A + +LL GA VD Sbjct: 314 HRASLFDHHELADYLISVGADINKIDSEGRSPLILATASASWNIVNLLLSKGAQVDIKDN 373 Query: 393 --------------------------------AMDKNKN--TPLHYAAGYGRKECVDLLL 316 MD++ + TPLHYA G V+ LL Sbjct: 374 FGRNFLHLTVQQPYGLKNLRPEFMQMQQIKELVMDEDNDGCTPLHYACRQGGPGSVNNLL 433 Query: 315 KHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLLEKDV 208 ++ ++ D K+P+ A + + L +D+ Sbjct: 434 GFNVSIHSKSKDKKSPLHFAASYGRINTCQRLLQDI 469 Score = 35.0 bits (79), Expect = 0.20 Identities = 27/101 (26%), Positives = 45/101 (44%), Gaps = 4/101 (3%) Frame = -1 Query: 564 VHHTASVGDGEGLK---KALDGGAD-KDEEDSEGRRALHFACGYGEFKCAEILLEAGAAV 397 +H A+ G E +K + G D + D LH A + + A+ L+ GA + Sbjct: 276 IHFAATQGATEIVKLMISSYSGSVDIVNTTDGCHETMLHRASLFDHHELADYLISVGADI 335 Query: 396 DAMDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGK 274 + +D +PL A V+LLL GA V +++ G+ Sbjct: 336 NKIDSEGRSPLILATASASWNIVNLLLSKGAQVDIKDNFGR 376
>PP16B_MOUSE (Q8VHQ3) Protein phosphatase 1 regulatory inhibitor subunit 16B| (TGF-beta-inhibited membrane-associated protein) (CAAX box protein TIMAP) Length = 568 Score = 59.3 bits (142), Expect = 1e-08 Identities = 34/96 (35%), Positives = 52/96 (54%) Frame = -1 Query: 507 GADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECV 328 G D D D +G LH A G + AE+LL+ G VD D + PLH AA +G+ Sbjct: 219 GQDLDWIDGQGATLLHIAGANGYLRAAELLLDHGVRVDVKDWDGWEPLHAAAFWGQMPMA 278 Query: 327 DLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 +LL+ HGA+++ + + PID+ ++E K+L Sbjct: 279 ELLVSHGASLSARTSMDEMPIDLC----EEEEFKVL 310 Score = 52.0 bits (123), Expect = 2e-06 Identities = 32/96 (33%), Positives = 47/96 (48%) Frame = -1 Query: 540 DGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLH 361 D E ++ L D + +G ALH C + ++LL GA V+A D TPLH Sbjct: 80 DAEEVRYFLKNKVSPDLCNEDGLTALHQCCIDNFEEIVKLLLSHGANVNAKDNELWTPLH 139 Query: 360 YAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAK 253 AA G V +L+++GA + N DG P D+ + Sbjct: 140 AAATCGHINLVKILVQYGADLLAVNSDGNMPYDLCE 175 Score = 38.5 bits (88), Expect = 0.018 Identities = 22/67 (32%), Positives = 33/67 (49%) Frame = -1 Query: 420 LLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQ 241 ++ AG +D +D T LH A G +LLL HG V +++ DG P+ A Q Sbjct: 215 MIAAGQDLDWIDGQGATLLHIAGANGYLRAAELLLDHGVRVDVKDWDGWEPLHAAAFWGQ 274 Query: 240 DEVLKLL 220 + +LL Sbjct: 275 MPMAELL 281 Score = 30.8 bits (68), Expect = 3.8 Identities = 27/88 (30%), Positives = 39/88 (44%), Gaps = 15/88 (17%) Frame = -1 Query: 438 FKCAEILLEAGAAVDAMD-----KNKNTP----------LHYAAGYGRKECVDLLLKHGA 304 F+ + LLEA DA + KNK +P LH +E V LLL HGA Sbjct: 66 FEASVALLEASLRNDAEEVRYFLKNKVSPDLCNEDGLTALHQCCIDNFEEIVKLLLSHGA 125 Query: 303 AVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 V ++ + TP+ A ++K+L Sbjct: 126 NVNAKDNELWTPLHAAATCGHINLVKIL 153
>FANK1_RAT (Q66H07) Fibronectin type 3 and ankyrin repeat domains 1 protein| Length = 344 Score = 59.3 bits (142), Expect = 1e-08 Identities = 36/98 (36%), Positives = 56/98 (57%), Gaps = 2/98 (2%) Frame = -1 Query: 507 GADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKN-TPL-HYAAGYGRKE 334 GA D D G ALH+A G + +++ G VD +D TPL +A G ++ Sbjct: 200 GASWDARDLGGCTALHWAADGGHCPVIDWMIKDGCEVDVVDTGSGWTPLMRVSAVTGSQK 259 Query: 333 CVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 LL++ GA V +++ DGKTP+ VA LNN +++++LL Sbjct: 260 VASLLIEAGADVNVRDKDGKTPLMVAVLNNHEQLVQLL 297 Score = 55.8 bits (133), Expect = 1e-07 Identities = 31/77 (40%), Positives = 47/77 (61%) Frame = -1 Query: 444 GEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPI 265 G K A +L+EAGA V+ DK+ TPL A ++ V LLL GA T++N GK + Sbjct: 256 GSQKVASLLIEAGADVNVRDKDGKTPLMVAVLNNHEQLVQLLLDKGADATVKNEFGKGVL 315 Query: 264 DVAKLNNQDEVLKLLEK 214 ++A++ ++ VL LLE+ Sbjct: 316 EMARVFDRQNVLSLLEE 332
>ACBD6_HUMAN (Q9BR61) Acyl-CoA-binding domain-containing protein 6| Length = 282 Score = 59.3 bits (142), Expect = 1e-08 Identities = 33/92 (35%), Positives = 49/92 (53%) Frame = -1 Query: 501 DKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDL 322 D + +D EGR LH+AC G + +LL+ A ++ D T LHYA+ + V+L Sbjct: 184 DVNVKDEEGRALLHWACDRGHKELVTVLLQHRADINCQDNEGQTALHYASACEFLDIVEL 243 Query: 321 LLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLK 226 LL+ GA TL++ DG P +V VL+ Sbjct: 244 LLQSGADPTLRDQDGCLPEEVTGCKTVSLVLQ 275 Score = 37.0 bits (84), Expect = 0.053 Identities = 19/60 (31%), Positives = 33/60 (55%) Frame = -1 Query: 399 VDAMDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 V+ D+ LH+A G KE V +LL+H A + Q+ +G+T + A ++++LL Sbjct: 185 VNVKDEEGRALLHWACDRGHKELVTVLLQHRADINCQDNEGQTALHYASACEFLDIVELL 244 Score = 33.5 bits (75), Expect = 0.59 Identities = 20/68 (29%), Positives = 34/68 (50%) Frame = -1 Query: 570 SIVHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDA 391 +++H G E + L AD + +D+EG+ ALH+A E+LL++GA Sbjct: 194 ALLHWACDRGHKELVTVLLQHRADINCQDNEGQTALHYASACEFLDIVELLLQSGADPTL 253 Query: 390 MDKNKNTP 367 D++ P Sbjct: 254 RDQDGCLP 261
>TRPA1_CAEEL (Q18297) Transient receptor potential cation channel subfamily A| member 1 homolog Length = 1193 Score = 59.3 bits (142), Expect = 1e-08 Identities = 38/121 (31%), Positives = 60/121 (49%), Gaps = 1/121 (0%) Frame = -1 Query: 570 SIVHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDA 391 S +H A G K LD GADK+ ++S + L A G+ + + L+ GA +++ Sbjct: 525 SALHLAARSGHDATTKVLLDNGADKEAKNSYQKTPLQVAVDSGKLETCQRLVAKGAQIES 584 Query: 390 MDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLK-LLEK 214 K T LH AA YG + V + G + ++ +GKT D+A N+ +V + LE Sbjct: 585 SSDTK-TVLHTAAFYGNESIVRYFIAEGVTIDRRDEEGKTAFDIACENDHKDVARAFLET 643 Query: 213 D 211 D Sbjct: 644 D 644 Score = 53.5 bits (127), Expect = 5e-07 Identities = 28/74 (37%), Positives = 43/74 (58%), Gaps = 2/74 (2%) Frame = -1 Query: 426 EILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAK-- 253 E LL+A AV+A D + TPLHYAA YG + V LLL A +N +G TP+ +A Sbjct: 50 EALLKAPLAVNAQDGDFMTPLHYAARYGNYDAVKLLLSKNALPNTKNREGDTPLHIASKY 109 Query: 252 LNNQDEVLKLLEKD 211 + ++ ++++D Sbjct: 110 IYGYSDICSIIDED 123 Score = 52.0 bits (123), Expect = 2e-06 Identities = 34/119 (28%), Positives = 59/119 (49%), Gaps = 2/119 (1%) Frame = -1 Query: 567 IVHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAA-VDA 391 ++H A G E LK ++ G +K+E + LH A + + L+E +D Sbjct: 297 LIHFAAEKGFLEVLKALVEAGGNKNELNEVKAVPLHVAAQMNQLEVVSYLIEEEKDNIDV 356 Query: 390 MDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDV-AKLNNQDEVLKLLE 217 +D+ TPL A + K+CV+ L+ A +T+ + D +TP+ + AK N V +L+ Sbjct: 357 VDEQGLTPLMMAVTHDSKKCVEYLIAKKANLTITDKDERTPVFIGAKFNALSSVEYILD 415 Score = 48.9 bits (115), Expect = 1e-05 Identities = 27/67 (40%), Positives = 41/67 (61%), Gaps = 1/67 (1%) Frame = -1 Query: 399 VDAMDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQ-DEVLKL 223 V+ +D+++NTP+H A G E + LL KHGA++T N D +T + A + Q V +L Sbjct: 449 VNMVDRDQNTPMHIVASNGYLEMMQLLQKHGASITQVNEDEETALHRAAIGGQTGAVRQL 508 Query: 222 LEKDVFL 202 LE D+ L Sbjct: 509 LEWDIRL 515 Score = 46.6 bits (109), Expect = 7e-05 Identities = 34/116 (29%), Positives = 51/116 (43%), Gaps = 17/116 (14%) Frame = -1 Query: 465 LHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQN 286 LH+A F L++ A VDA D NK TPL A +G +E + L+K + VT ++ Sbjct: 160 LHYAAMKSNFSALHALIKLKADVDAEDDNKMTPLLLACVHGSQEIIQELIKANSNVTKRD 219 Query: 285 MDGKTPIDVAKLNNQDEVLKLL-----------------EKDVFL*IASLGSHEET 169 T + L + E L+++ EK L +A G+H ET Sbjct: 220 QRLNTVFHIVALRGEPEYLEMMMDHDPVEAIKALNLFNNEKKTPLRMAVEGNHPET 275 Score = 43.5 bits (101), Expect = 6e-04 Identities = 35/141 (24%), Positives = 61/141 (43%), Gaps = 24/141 (17%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFAC----GYGEF------------- 436 +H+ A G+ + +K L A + ++ EG LH A GY + Sbjct: 70 LHYAARYGNYDAVKLLLSKNALPNTKNREGDTPLHIASKYIYGYSDICSIIDEDQADSAR 129 Query: 435 -------KCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDG 277 K L+ A +D ++K + TPLHYAA + L+K A V ++ + Sbjct: 130 KYNTATKKIINALVSENAEIDPVNKYQLTPLHYAAMKSNFSALHALIKLKADVDAEDDNK 189 Query: 276 KTPIDVAKLNNQDEVLKLLEK 214 TP+ +A ++ E+++ L K Sbjct: 190 MTPLLLACVHGSQEIIQELIK 210 Score = 43.5 bits (101), Expect = 6e-04 Identities = 23/76 (30%), Positives = 40/76 (52%), Gaps = 1/76 (1%) Frame = -1 Query: 570 SIVHHTASVGDGEGLKKAL-DGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVD 394 SI+H +A G+ L++AL + +D + LH+A YG + ++LL A + Sbjct: 34 SIIHQSAREGNVNALQEALLKAPLAVNAQDGDFMTPLHYAARYGNYDAVKLLLSKNALPN 93 Query: 393 AMDKNKNTPLHYAAGY 346 ++ +TPLH A+ Y Sbjct: 94 TKNREGDTPLHIASKY 109 Score = 42.0 bits (97), Expect = 0.002 Identities = 25/88 (28%), Positives = 41/88 (46%) Frame = -1 Query: 489 EDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLLKH 310 +D G ALH A G ++LL+ GA +A + + TPL A G+ E L+ Sbjct: 519 KDEMGNSALHLAARSGHDATTKVLLDNGADKEAKNSYQKTPLQVAVDSGKLETCQRLVAK 578 Query: 309 GAAVTLQNMDGKTPIDVAKLNNQDEVLK 226 GA + + D KT + A + +++ Sbjct: 579 GAQIE-SSSDTKTVLHTAAFYGNESIVR 605 Score = 35.8 bits (81), Expect = 0.12 Identities = 22/86 (25%), Positives = 44/86 (51%), Gaps = 1/86 (1%) Frame = -1 Query: 474 RRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLLKHGA-AV 298 + +HFA G + + L+EAG + +++ K PLH AA + E V L++ + Sbjct: 295 KELIHFAAEKGFLEVLKALVEAGGNKNELNEVKAVPLHVAAQMNQLEVVSYLIEEEKDNI 354 Query: 297 TLQNMDGKTPIDVAKLNNQDEVLKLL 220 + + G TP+ +A ++ + ++ L Sbjct: 355 DVVDEQGLTPLMMAVTHDSKKCVEYL 380 Score = 34.7 bits (78), Expect = 0.26 Identities = 27/123 (21%), Positives = 45/123 (36%), Gaps = 29/123 (23%) Frame = -1 Query: 495 DEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLL 316 D D +G L A + KC E L+ A + DK++ TP+ A + V+ +L Sbjct: 355 DVVDEQGLTPLMMAVTHDSKKCVEYLIAKKANLTITDKDERTPVFIGAKFNALSSVEYIL 414 Query: 315 KH-----------------------------GAAVTLQNMDGKTPIDVAKLNNQDEVLKL 223 H V + + D TP+ + N E+++L Sbjct: 415 DHLRKKNKETERSALKSPTRNTLRIVSEDVRRTMVNMVDRDQNTPMHIVASNGYLEMMQL 474 Query: 222 LEK 214 L+K Sbjct: 475 LQK 477
>INVSB_XENLA (Q71S21) Inversin-B| Length = 1002 Score = 59.3 bits (142), Expect = 1e-08 Identities = 35/89 (39%), Positives = 47/89 (52%) Frame = -1 Query: 486 DSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLLKHG 307 D G ALH A G+ ILLE A DA+D K+TPL A G +E + L+K G Sbjct: 350 DKYGGTALHAASLSGQITTVRILLENRAQADAVDVMKHTPLFRACEMGHREVIATLIKGG 409 Query: 306 AAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 A V L + DG++P+ A L V ++L Sbjct: 410 AKVHLVDKDGRSPLHWAALGGNANVCQIL 438 Score = 58.5 bits (140), Expect = 2e-08 Identities = 40/130 (30%), Positives = 65/130 (50%), Gaps = 2/130 (1%) Frame = -1 Query: 570 SIVHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDA 391 S +H A G+ + ++ + D +D EGR L A G C E+L+E A + Sbjct: 421 SPLHWAALGGNANVCQILIENNINPDAQDYEGRTPLQCAAYGGYIGCMEVLMENKADPNI 480 Query: 390 MDKNKNTPLHYAAGYGRKECVDLLLKHGAAVT-LQNMDGK-TPIDVAKLNNQDEVLKLLE 217 DKN T LH++ G + V LLL + A ++N + + TP+D A L EV++ + Sbjct: 481 QDKNGRTALHWSCNNGYLDAVKLLLGYNAFPNQMENTEERYTPLDYALLGGHQEVIQFML 540 Query: 216 KDVFL*IASL 187 + L IA++ Sbjct: 541 EHGALSIAAI 550 Score = 57.8 bits (138), Expect = 3e-08 Identities = 34/102 (33%), Positives = 54/102 (52%), Gaps = 2/102 (1%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLE--AGAAVDA 391 +H A G+ LK L AD D ALH + + + +C +LL+ VDA Sbjct: 81 LHLAAQTGNHRLLKLLLSRKADCTHRDLCDITALHLSTRHQDTQCLVLLLKYTPPGQVDA 140 Query: 390 MDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPI 265 D+ K T LH++A Y R + V LL++HG+ + + + +GK P+ Sbjct: 141 QDQRKQTALHWSAYYNRPQHVRLLVRHGSNIGIPDTEGKIPL 182 Score = 54.7 bits (130), Expect = 2e-07 Identities = 41/139 (29%), Positives = 64/139 (46%), Gaps = 14/139 (10%) Frame = -1 Query: 546 VGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTP 367 +G E + + GGA D +GR LH+A G +IL+E DA D TP Sbjct: 396 MGHREVIATLIKGGAKVHLVDKDGRSPLHWAALGGNANVCQILIENNINPDAQDYEGRTP 455 Query: 366 LHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL----------- 220 L AA G C+++L+++ A +Q+ +G+T + + N + +KLL Sbjct: 456 LQCAAYGGYIGCMEVLMENKADPNIQDKNGRTALHWSCNNGYLDAVKLLLGYNAFPNQME 515 Query: 219 ---EKDVFL*IASLGSHEE 172 E+ L A LG H+E Sbjct: 516 NTEERYTPLDYALLGGHQE 534 Score = 47.4 bits (111), Expect = 4e-05 Identities = 30/102 (29%), Positives = 49/102 (48%), Gaps = 1/102 (0%) Frame = -1 Query: 558 HTASV-GDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDK 382 H AS+ G ++ L+ A D D L AC G + L++ GA V +DK Sbjct: 358 HAASLSGQITTVRILLENRAQADAVDVMKHTPLFRACEMGHREVIATLIKGGAKVHLVDK 417 Query: 381 NKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVA 256 + +PLH+AA G +L+++ Q+ +G+TP+ A Sbjct: 418 DGRSPLHWAALGGNANVCQILIENNINPDAQDYEGRTPLQCA 459 Score = 47.4 bits (111), Expect = 4e-05 Identities = 31/94 (32%), Positives = 47/94 (50%) Frame = -1 Query: 495 DEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLL 316 D+ED GR L ++ CAE LL+ GA V+ D++ T LH AA G + LLL Sbjct: 38 DQEDQLGRTPLMYSVLGDRRSCAEALLKHGAKVNRPDRSGRTALHLAAQTGNHRLLKLLL 97 Query: 315 KHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLLEK 214 A T +++ T + ++ + + L LL K Sbjct: 98 SRKADCTHRDLCDITALHLSTRHQDTQCLVLLLK 131 Score = 44.3 bits (103), Expect = 3e-04 Identities = 22/68 (32%), Positives = 35/68 (51%) Frame = -1 Query: 423 ILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNN 244 ++ + +D D+ TPL Y+ R+ C + LLKHGA V + G+T + +A Sbjct: 29 LIASSPQVIDQEDQLGRTPLMYSVLGDRRSCAEALLKHGAKVNRPDRSGRTALHLAAQTG 88 Query: 243 QDEVLKLL 220 +LKLL Sbjct: 89 NHRLLKLL 96 Score = 43.9 bits (102), Expect = 4e-04 Identities = 26/98 (26%), Positives = 48/98 (48%), Gaps = 6/98 (6%) Frame = -1 Query: 495 DEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKE------ 334 D +D + ALH++ Y + +L+ G+ + D PLH+AAG+ E Sbjct: 139 DAQDQRKQTALHWSAYYNRPQHVRLLVRHGSNIGIPDTEGKIPLHWAAGHKDPEAALTVR 198 Query: 333 CVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 C+ + + Q+ +G+TP+ +A + EV++LL Sbjct: 199 CLFEAAPTESLLNWQDYEGRTPLHLAVGDGNQEVVRLL 236 Score = 41.2 bits (95), Expect = 0.003 Identities = 34/114 (29%), Positives = 55/114 (48%), Gaps = 4/114 (3%) Frame = -1 Query: 549 SVGDG-EGLKKALDG--GADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDA-MDK 382 +VGDG + + + L G + D+ R LH+A G A +LLE + + D Sbjct: 224 AVGDGNQEVVRLLTSYRGCNVAPYDNLFRTPLHWAALLGHTPIAHLLLERNNSPNIPSDS 283 Query: 381 NKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 TPLHYAA + V +LL H + +++G+T + A DEV++ + Sbjct: 284 QGATPLHYAAQGNCPDTVRVLLSHPSVRDEADLEGRTALMWAAGKGSDEVVRTM 337 Score = 38.5 bits (88), Expect = 0.018 Identities = 34/122 (27%), Positives = 57/122 (46%), Gaps = 7/122 (5%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCA---EILLEAG---A 403 +H +A + ++ + G++ D+EG+ LH+A G+ + + A L EA + Sbjct: 149 LHWSAYYNRPQHVRLLVRHGSNIGIPDTEGKIPLHWAAGHKDPEAALTVRCLFEAAPTES 208 Query: 402 AVDAMDKNKNTPLHYAAGYGRKECVDLLLKH-GAAVTLQNMDGKTPIDVAKLNNQDEVLK 226 ++ D TPLH A G G +E V LL + G V + +TP+ A L + Sbjct: 209 LLNWQDYEGRTPLHLAVGDGNQEVVRLLTSYRGCNVAPYDNLFRTPLHWAALLGHTPIAH 268 Query: 225 LL 220 LL Sbjct: 269 LL 270 Score = 36.2 bits (82), Expect = 0.091 Identities = 26/91 (28%), Positives = 40/91 (43%), Gaps = 2/91 (2%) Frame = -1 Query: 486 DSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLLKHG 307 DS+G LH+A +LL + D D T L +AAG G E V +L+ Sbjct: 282 DSQGATPLHYAAQGNCPDTVRVLLSHPSVRDEADLEGRTALMWAAGKGSDEVVRTMLELN 341 Query: 306 AAVTLQNMD--GKTPIDVAKLNNQDEVLKLL 220 + + D G T + A L+ Q +++L Sbjct: 342 PKLEVNRTDKYGGTALHAASLSGQITTVRIL 372
>ASB5_HUMAN (Q8WWX0) Ankyrin repeat and SOCS box protein 5 (ASB-5)| Length = 329 Score = 59.3 bits (142), Expect = 1e-08 Identities = 44/116 (37%), Positives = 57/116 (49%) Frame = -1 Query: 570 SIVHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDA 391 S H AS G E L + G D D+E L+ AC +F C LL AGA V Sbjct: 170 SPTHEAASKGHHECLDILISWGIDVDQEIPHLGTPLYVACMSQQFHCIWKLLYAGADVQK 229 Query: 390 MDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKL 223 K +TPLH AA E V+LLL+ GA + +N + PIDVA ++ E + L Sbjct: 230 -GKYWDTPLHAAAQQSSTEIVNLLLEFGADINAKNTELLRPIDVATSSSMVERILL 284 Score = 52.4 bits (124), Expect = 1e-06 Identities = 34/95 (35%), Positives = 47/95 (49%) Frame = -1 Query: 570 SIVHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDA 391 S +H AS G L+ L G + + + LH AC CA LLEAGA V+A Sbjct: 72 SPLHEAASQGRLLALRTLLSQGYNVNAVTLDHVTPLHEACLGDHVACARTLLEAGANVNA 131 Query: 390 MDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQN 286 + + TPL A G C +LLL++GA L++ Sbjct: 132 ITIDGVTPLFNACSQGSPSCAELLLEYGAKAQLES 166 Score = 40.0 bits (92), Expect = 0.006 Identities = 44/162 (27%), Positives = 59/162 (36%), Gaps = 6/162 (3%) Frame = -1 Query: 474 RRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLLKHGAAVT 295 R LH A G LL G V+A+ + TPLH A C LL+ GA V Sbjct: 71 RSPLHEAASQGRLLALRTLLSQGYNVNAVTLDHVTPLHEACLGDHVACARTLLEAGANVN 130 Query: 294 LQNMDGKTPIDVAKLNNQDEVLKLLEKDVFL*IASLGSHEETWPSSCFTSLWHWLDSHTR 115 +DG TP+ A +LL L + SC S H S Sbjct: 131 AITIDGVTPLFNACSQGSPSCAELL----------LEYGAKAQLESCLPSPTHEAASKGH 180 Query: 114 IGILFVV*EYTTCVSWPAGRL-AEVRTAC-----YCIWRLVY 7 L ++ + V L + AC +CIW+L+Y Sbjct: 181 HECLDILISWGIDVDQEIPHLGTPLYVACMSQQFHCIWKLLY 222
>LIN12_CAEEL (P14585) Protein lin-12 precursor (Abnormal cell lineage protein 12)| Length = 1429 Score = 58.9 bits (141), Expect = 1e-08 Identities = 35/108 (32%), Positives = 55/108 (50%), Gaps = 1/108 (0%) Frame = -1 Query: 534 EGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILL-EAGAAVDAMDKNKNTPLHY 358 +G K DG A KD E +GR ALH+A + L+ E G+ D D++ TP+ Sbjct: 1188 KGAKVDYDGAARKDSEKYKGRTALHYAAQVSNMPIVKYLVGEKGSNKDKQDEDGKTPIML 1247 Query: 357 AAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLLEK 214 AA GR E V L++ GA+V + T +A+ NN ++ + ++ Sbjct: 1248 AAQEGRIEVVMYLIQQGASVEAVDATDHTARQLAQANNHHNIVDIFDR 1295 Score = 38.5 bits (88), Expect = 0.018 Identities = 23/61 (37%), Positives = 34/61 (55%) Frame = -1 Query: 429 AEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKL 250 A+ + AGA V+AMD ++NTPL A R+ V L+K GA T+ N ++ + A Sbjct: 1077 AKECIAAGADVNAMDCDENTPLMLAVLARRRRLVAYLMKAGADPTIYNKSERSALHQAAA 1136 Query: 249 N 247 N Sbjct: 1137 N 1137
>INVS_MOUSE (O89019) Inversin (Inversion of embryo turning protein)| (Nephrocystin-2) Length = 1062 Score = 58.9 bits (141), Expect = 1e-08 Identities = 37/111 (33%), Positives = 59/111 (53%), Gaps = 2/111 (1%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLE--AGAAVDA 391 +H A G+ +K L A+ ++D E LH + + KC +LL+ A VD Sbjct: 85 LHLAAQKGNYRFMKLLLTRRANWMQKDLEEMTPLHLSTRHRSPKCLALLLKFMAPGEVDT 144 Query: 390 MDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQD 238 DKNK T LH++A Y E LL+KH + + + +++GK P+ A N++D Sbjct: 145 QDKNKQTALHWSAYYNNPEHAKLLIKHDSNIGIPDVEGKIPLHWA-ANHKD 194 Score = 57.4 bits (137), Expect = 4e-08 Identities = 40/120 (33%), Positives = 61/120 (50%), Gaps = 1/120 (0%) Frame = -1 Query: 570 SIVHHTASVGDGEGLKKALDGG-ADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVD 394 S VH A GD L++ + G A +D+ED GR L + CA+ LL+AGA V+ Sbjct: 16 SQVHAAAVNGDKGALQRLIVGNSALRDKEDRFGRTPLMYCVLADRVDCADALLKAGADVN 75 Query: 393 AMDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLLEK 214 D ++ T LH AA G + LLL A ++++ TP+ ++ + + L LL K Sbjct: 76 KTDHSRRTALHLAAQKGNYRFMKLLLTRRANWMQKDLEEMTPLHLSTRHRSPKCLALLLK 135 Score = 56.2 bits (134), Expect = 8e-08 Identities = 34/100 (34%), Positives = 50/100 (50%) Frame = -1 Query: 519 ALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGR 340 +L D + D G ALH A G ++LL+ A VDA D K+TPL A G Sbjct: 343 SLKSDIDINMSDKYGGTALHAAALSGHVSTVKLLLDNDAQVDATDVMKHTPLFRACEMGH 402 Query: 339 KECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 ++ + L+K GA V L + DG + + A L +V ++L Sbjct: 403 RDVIQTLIKGGARVDLVDQDGHSLLHWAALGGNADVCQIL 442 Score = 51.6 bits (122), Expect = 2e-06 Identities = 35/130 (26%), Positives = 61/130 (46%), Gaps = 2/130 (1%) Frame = -1 Query: 570 SIVHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDA 391 S++H A G+ + + ++ + + +D GR L A G C +L+E A + Sbjct: 425 SLLHWAALGGNADVCQILIENKINPNVQDYAGRTPLQCAAYGGYINCMAVLMENNADPNI 484 Query: 390 MDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTL--QNMDGKTPIDVAKLNNQDEVLKLLE 217 DK T LH++ G + + LLL A N + TP+D A L + EV++ + Sbjct: 485 QDKEGRTALHWSCNNGYLDAIKLLLDFAAFPNQMENNEERYTPLDYALLGERHEVIQFML 544 Query: 216 KDVFL*IASL 187 + L IA++ Sbjct: 545 EHGALSIAAI 554 Score = 49.7 bits (117), Expect = 8e-06 Identities = 31/109 (28%), Positives = 54/109 (49%) Frame = -1 Query: 546 VGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTP 367 +G + ++ + GGA D D +G LH+A G +IL+E + D TP Sbjct: 400 MGHRDVIQTLIKGGARVDLVDQDGHSLLHWAALGGNADVCQILIENKINPNVQDYAGRTP 459 Query: 366 LHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 L AA G C+ +L+++ A +Q+ +G+T + + N + +KLL Sbjct: 460 LQCAAYGGYINCMAVLMENNADPNIQDKEGRTALHWSCNNGYLDAIKLL 508 Score = 49.7 bits (117), Expect = 8e-06 Identities = 30/103 (29%), Positives = 50/103 (48%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMD 385 +H A G +K LD A D D L AC G + L++ GA VD +D Sbjct: 361 LHAAALSGHVSTVKLLLDNDAQVDATDVMKHTPLFRACEMGHRDVIQTLIKGGARVDLVD 420 Query: 384 KNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVA 256 ++ ++ LH+AA G + +L+++ +Q+ G+TP+ A Sbjct: 421 QDGHSLLHWAALGGNADVCQILIENKINPNVQDYAGRTPLQCA 463 Score = 47.8 bits (112), Expect = 3e-05 Identities = 30/91 (32%), Positives = 46/91 (50%), Gaps = 2/91 (2%) Frame = -1 Query: 489 EDSEGRRALHFACGYGEFKCAEILLEAGAA-VDAMDKNKNTPLHYAAGYGRKECVDLLLK 313 +D EGR LHFA G ++L + + + D TPLH+AA G + V LLL+ Sbjct: 217 QDYEGRTPLHFAVADGNLTVVDVLTSYESCNITSYDNLFRTPLHWAALLGHAQIVHLLLE 276 Query: 312 HGAAVTL-QNMDGKTPIDVAKLNNQDEVLKL 223 + T+ + G TP+ A +N E +K+ Sbjct: 277 RNKSGTIPSDSQGATPLHYAAQSNFAETVKV 307 Score = 40.4 bits (93), Expect = 0.005 Identities = 27/90 (30%), Positives = 42/90 (46%), Gaps = 1/90 (1%) Frame = -1 Query: 486 DSEGRRALHFACGYGEFKCAEILLEAG-AAVDAMDKNKNTPLHYAAGYGRKECVDLLLKH 310 D+ R LH+A G + +LLE + D TPLHYAA E V + L+H Sbjct: 252 DNLFRTPLHWAALLGHAQIVHLLLERNKSGTIPSDSQGATPLHYAAQSNFAETVKVFLQH 311 Query: 309 GAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 + +++G+T A D+VL+ + Sbjct: 312 PSVKDDSDLEGRTSFMWAAGKGNDDVLRTM 341 Score = 35.0 bits (79), Expect = 0.20 Identities = 24/91 (26%), Positives = 40/91 (43%), Gaps = 2/91 (2%) Frame = -1 Query: 486 DSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVD--LLLK 313 DS+G LH+A + ++ L+ + D D T +AAG G + + L LK Sbjct: 286 DSQGATPLHYAAQSNFAETVKVFLQHPSVKDDSDLEGRTSFMWAAGKGNDDVLRTMLSLK 345 Query: 312 HGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 + + + G T + A L+ +KLL Sbjct: 346 SDIDINMSDKYGGTALHAAALSGHVSTVKLL 376
>INVSA_XENLA (Q71S22) Inversin-A| Length = 1007 Score = 58.9 bits (141), Expect = 1e-08 Identities = 36/99 (36%), Positives = 50/99 (50%) Frame = -1 Query: 516 LDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRK 337 LD + + D G ALH A G+ ILLE VDA+D K+T L A G + Sbjct: 340 LDPELEVNRTDKYGGTALHAASLSGQITTVRILLENRVQVDAVDVMKHTALFRACEMGHR 399 Query: 336 ECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 E + L+K GA V L + DG++P+ A L V ++L Sbjct: 400 EVISTLIKGGAKVHLVDKDGRSPLHWAALGGNANVCQIL 438 Score = 58.5 bits (140), Expect = 2e-08 Identities = 40/130 (30%), Positives = 65/130 (50%), Gaps = 2/130 (1%) Frame = -1 Query: 570 SIVHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDA 391 S +H A G+ + ++ + D +D EGR L A G C E+L+E A + Sbjct: 421 SPLHWAALGGNANVCQILIENNINPDAQDYEGRTPLQCAAYGGYIGCMEVLMENKADPNI 480 Query: 390 MDKNKNTPLHYAAGYGRKECVDLLLKHGAAVT-LQNMDGK-TPIDVAKLNNQDEVLKLLE 217 DKN T LH++ G + V LLL + A ++N + + TP+D A L EV++ + Sbjct: 481 QDKNGRTALHWSCNNGYLDAVKLLLGYSAFPNQMENTEERYTPLDYALLGGHQEVIQFML 540 Query: 216 KDVFL*IASL 187 + L IA++ Sbjct: 541 EHGALSIAAI 550 Score = 57.4 bits (137), Expect = 4e-08 Identities = 32/102 (31%), Positives = 53/102 (51%), Gaps = 2/102 (1%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLE--AGAAVDA 391 +H A G+ LK L AD D A+H + + + +C ++L+ VDA Sbjct: 81 LHLAAQTGNHRLLKLLLSRKADCTHRDLRDITAVHLSTRHQDTRCLALILKYTPPGQVDA 140 Query: 390 MDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPI 265 D+ K T LH++A Y R V LL++HG+ + + + +GK P+ Sbjct: 141 QDQRKQTALHWSAYYNRPRHVRLLVRHGSNIGIPDTEGKIPL 182 Score = 56.6 bits (135), Expect = 6e-08 Identities = 44/151 (29%), Positives = 69/151 (45%), Gaps = 19/151 (12%) Frame = -1 Query: 567 IVHHTA-----SVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGA 403 ++ HTA +G E + + GGA D +GR LH+A G +IL+E Sbjct: 384 VMKHTALFRACEMGHREVISTLIKGGAKVHLVDKDGRSPLHWAALGGNANVCQILIENNI 443 Query: 402 AVDAMDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKL 223 DA D TPL AA G C+++L+++ A +Q+ +G+T + + N + +KL Sbjct: 444 NPDAQDYEGRTPLQCAAYGGYIGCMEVLMENKADPNIQDKNGRTALHWSCNNGYLDAVKL 503 Query: 222 L--------------EKDVFL*IASLGSHEE 172 L E+ L A LG H+E Sbjct: 504 LLGYSAFPNQMENTEERYTPLDYALLGGHQE 534 Score = 48.5 bits (114), Expect = 2e-05 Identities = 37/120 (30%), Positives = 55/120 (45%), Gaps = 1/120 (0%) Frame = -1 Query: 570 SIVHHTASVGDGEGLKKALDGGADK-DEEDSEGRRALHFACGYGEFKCAEILLEAGAAVD 394 S V A GD L K + + D+ED GR L ++ CAE LL+ GA V+ Sbjct: 12 SPVQAAAVTGDKTTLLKLIASSPEVIDQEDQLGRTPLMYSVLGDRRSCAEALLKHGAQVN 71 Query: 393 AMDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLLEK 214 D++ T LH AA G + LLL A T +++ T + ++ + L L+ K Sbjct: 72 HPDRSGRTALHLAAQTGNHRLLKLLLSRKADCTHRDLRDITAVHLSTRHQDTRCLALILK 131 Score = 47.8 bits (112), Expect = 3e-05 Identities = 30/102 (29%), Positives = 49/102 (48%), Gaps = 1/102 (0%) Frame = -1 Query: 558 HTASV-GDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDK 382 H AS+ G ++ L+ D D AL AC G + L++ GA V +DK Sbjct: 358 HAASLSGQITTVRILLENRVQVDAVDVMKHTALFRACEMGHREVISTLIKGGAKVHLVDK 417 Query: 381 NKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVA 256 + +PLH+AA G +L+++ Q+ +G+TP+ A Sbjct: 418 DGRSPLHWAALGGNANVCQILIENNINPDAQDYEGRTPLQCA 459 Score = 45.4 bits (106), Expect = 1e-04 Identities = 29/98 (29%), Positives = 50/98 (51%), Gaps = 6/98 (6%) Frame = -1 Query: 495 DEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKEC---VD 325 D +D + ALH++ Y + +L+ G+ + D PLH+AAG+ E V Sbjct: 139 DAQDQRKQTALHWSAYYNRPRHVRLLVRHGSNIGIPDTEGKIPLHWAAGHKDPEAALTVR 198 Query: 324 LLLKHGAAVTL---QNMDGKTPIDVAKLNNQDEVLKLL 220 LL+ +L Q+ +G+TP+ +A + EV++LL Sbjct: 199 CLLEAAPTESLLNWQDYEGRTPLHLAVGDGNQEVVRLL 236 Score = 40.0 bits (92), Expect = 0.006 Identities = 37/118 (31%), Positives = 57/118 (48%), Gaps = 5/118 (4%) Frame = -1 Query: 549 SVGDG-EGLKKALDG--GADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDA-MDK 382 +VGDG + + + L G + D+ R LH+A G A +LLE + + D Sbjct: 224 AVGDGNQEVVRLLTSYRGCNVAPYDNLFRTPLHWAALLGYTPIAHLLLETNNSPNIPSDS 283 Query: 381 NKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLK-LLEKD 211 TPLHYAA + V +LL H + +++G+T A DEV++ +LE D Sbjct: 284 QGATPLHYAAQGNCPDTVRVLLSHISVRDEADLEGRTAFMWAAGKGSDEVVRTMLELD 341
>ASB16_HUMAN (Q96NS5) Ankyrin repeat and SOCS box protein 16 (ASB-16)| Length = 453 Score = 58.9 bits (141), Expect = 1e-08 Identities = 36/104 (34%), Positives = 56/104 (53%), Gaps = 1/104 (0%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVD-AM 388 +H + + ++ L GA + EG LH +CA++LLEAGA V+ A Sbjct: 147 LHEACARAQFDCVRLLLTFGAKANVLTEEGTTPLHLCTIPESLQCAKLLLEAGATVNLAA 206 Query: 387 DKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVA 256 +++ TPLH AA G ++ V L L+HGA V L+ G+T ++ A Sbjct: 207 GESQETPLHVAAARGLEQHVALYLEHGADVGLRTSQGETALNAA 250 Score = 57.0 bits (136), Expect = 5e-08 Identities = 41/117 (35%), Positives = 56/117 (47%), Gaps = 8/117 (6%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFK--------CAEILLEA 409 +H A+ G + + L+ GAD S+G AL+ AC E A LLEA Sbjct: 214 LHVAAARGLEQHVALYLEHGADVGLRTSQGETALNAACAGAEGPGSCRRHQAAARRLLEA 273 Query: 408 GAAVDAMDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQD 238 GA A + ++TPLH A G +LLL++GA + N G TP+D A QD Sbjct: 274 GADARAAGRKRHTPLHNACASGCGGLAELLLRYGARAEVPNGAGHTPMDCALQAVQD 330 Score = 52.4 bits (124), Expect = 1e-06 Identities = 30/86 (34%), Positives = 43/86 (50%), Gaps = 1/86 (1%) Frame = -1 Query: 477 GRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLLKHGAAV 298 GR ALH AC +F C +LL GA + + + TPLH +C LLL+ GA V Sbjct: 143 GRAALHEACARAQFDCVRLLLTFGAKANVLTEEGTTPLHLCTIPESLQCAKLLLEAGATV 202 Query: 297 TLQNMDG-KTPIDVAKLNNQDEVLKL 223 L + +TP+ VA ++ + L Sbjct: 203 NLAAGESQETPLHVAAARGLEQHVAL 228 Score = 39.3 bits (90), Expect = 0.011 Identities = 26/82 (31%), Positives = 37/82 (45%) Frame = -1 Query: 465 LHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQN 286 L A G CA L+ GA +DA + LH A + +CV LLL GA + Sbjct: 115 LAIATARGYTDCARHLIRQGAELDARVGGR-AALHEACARAQFDCVRLLLTFGAKANVLT 173 Query: 285 MDGKTPIDVAKLNNQDEVLKLL 220 +G TP+ + + + KLL Sbjct: 174 EEGTTPLHLCTIPESLQCAKLL 195
>MTPN_HUMAN (P58546) Myotrophin (V-1 protein)| Length = 117 Score = 58.9 bits (141), Expect = 1e-08 Identities = 35/94 (37%), Positives = 49/94 (52%) Frame = -1 Query: 543 GDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPL 364 GD + +K + G D + GR+ LH+A G+ + E LL GA ++A DK+ TPL Sbjct: 12 GDLDEVKDYVAKGEDVNRTLEGGRKPLHYAADCGQLEILEFLLLKGADINAPDKHHITPL 71 Query: 363 HYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPID 262 A G CV LLL GA T++ DG T + Sbjct: 72 LSAVYEGHVSCVKLLLSKGADKTVKGPDGLTAFE 105 Score = 31.6 bits (70), Expect = 2.2 Identities = 18/50 (36%), Positives = 25/50 (50%) Frame = -1 Query: 369 PLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 PLHYAA G+ E ++ LL GA + + TP+ A +KLL Sbjct: 37 PLHYAADCGQLEILEFLLLKGADINAPDKHHITPLLSAVYEGHVSCVKLL 86
>MTPN_CANFA (Q863Z4) Myotrophin| Length = 117 Score = 58.9 bits (141), Expect = 1e-08 Identities = 35/94 (37%), Positives = 49/94 (52%) Frame = -1 Query: 543 GDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPL 364 GD + +K + G D + GR+ LH+A G+ + E LL GA ++A DK+ TPL Sbjct: 12 GDLDEVKDYVAKGEDVNRTLEGGRKPLHYAADCGQLEILEFLLLKGADINAPDKHHITPL 71 Query: 363 HYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPID 262 A G CV LLL GA T++ DG T + Sbjct: 72 LSAVYEGHVSCVKLLLSKGADKTVKGPDGLTAFE 105 Score = 31.6 bits (70), Expect = 2.2 Identities = 18/50 (36%), Positives = 25/50 (50%) Frame = -1 Query: 369 PLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 PLHYAA G+ E ++ LL GA + + TP+ A +KLL Sbjct: 37 PLHYAADCGQLEILEFLLLKGADINAPDKHHITPLLSAVYEGHVSCVKLL 86
>FANK1_MOUSE (Q9DAM9) Fibronectin type 3 and ankyrin repeat domains 1 protein| (Germ cell-specific gene 1 protein) (GSG1) Length = 344 Score = 58.5 bits (140), Expect = 2e-08 Identities = 35/98 (35%), Positives = 56/98 (57%), Gaps = 2/98 (2%) Frame = -1 Query: 507 GADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKN-TPL-HYAAGYGRKE 334 GA + D G ALH+A G + +++ G VD +D TPL +A G ++ Sbjct: 200 GASWEARDLGGCTALHWAADGGHCSVIDWMIKDGCEVDVVDTGSGWTPLMRVSAVTGSQK 259 Query: 333 CVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 LL++ GA V +++ DGKTP+ VA LNN +++++LL Sbjct: 260 VASLLIEAGADVNIKDKDGKTPLMVAVLNNHEQLVQLL 297 Score = 55.5 bits (132), Expect = 1e-07 Identities = 31/77 (40%), Positives = 47/77 (61%) Frame = -1 Query: 444 GEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPI 265 G K A +L+EAGA V+ DK+ TPL A ++ V LLL GA T++N GK + Sbjct: 256 GSQKVASLLIEAGADVNIKDKDGKTPLMVAVLNNHEQLVQLLLDKGADATVKNEFGKGVL 315 Query: 264 DVAKLNNQDEVLKLLEK 214 ++A++ ++ VL LLE+ Sbjct: 316 EMARVFDRQNVLSLLEE 332
>CDN2C_MOUSE (Q60772) Cyclin-dependent kinase 6 inhibitor (p18-INK6)| (Cyclin-dependent kinase 4 inhibitor C) (p18-INK4c) Length = 168 Score = 58.5 bits (140), Expect = 2e-08 Identities = 38/111 (34%), Positives = 57/111 (51%), Gaps = 1/111 (0%) Frame = -1 Query: 546 VGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTP 367 +G+ E ++ L GA+ + +D G +H A G + LLE A V+ D N P Sbjct: 47 LGNPEIARRLLLRGANPNLKDGTGFAVIHDAARAGFLDTVQALLEFQADVNIEDNEGNLP 106 Query: 366 LHYAAGYGRKECVDLLLKHGAA-VTLQNMDGKTPIDVAKLNNQDEVLKLLE 217 LH AA G V+ L+KH A V +N G T D+A+ ++EV+ L+E Sbjct: 107 LHLAAKEGHLPVVEFLMKHTACNVGHRNHKGDTAFDLARFYGRNEVISLME 157 Score = 41.2 bits (95), Expect = 0.003 Identities = 29/97 (29%), Positives = 46/97 (47%), Gaps = 3/97 (3%) Frame = -1 Query: 570 SIVHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAA-VD 394 +++H A G + ++ L+ AD + ED+EG LH A G E L++ A V Sbjct: 72 AVIHDAARAGFLDTVQALLEFQADVNIEDNEGNLPLHLAAKEGHLPVVEFLMKHTACNVG 131 Query: 393 AMDKNKNTPLHYAAGYGRKECVDLLLKH--GAAVTLQ 289 + +T A YGR E + L+ + G A +LQ Sbjct: 132 HRNHKGDTAFDLARFYGRNEVISLMEANGVGGATSLQ 168
>Y1425_THEVO (Q978J0) Hypothetical ANK-repeat protein TV1425| Length = 189 Score = 58.2 bits (139), Expect = 2e-08 Identities = 36/108 (33%), Positives = 59/108 (54%), Gaps = 4/108 (3%) Frame = -1 Query: 531 GLKKALDGGADK----DEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPL 364 G++ A+D + +++D EG AL +A AE LL G+ V+ D + TPL Sbjct: 43 GMENAIDKLVENFDKLEDKDIEGSTALIWAVKNNRLGIAEKLLSKGSNVNTKDFSGKTPL 102 Query: 363 HYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 ++ +G E LL+HGA V +N++G+TP+ VA + E++K L Sbjct: 103 MWSIIFGYSEMSYFLLEHGANVNDRNLEGETPLIVASKYGRSEIVKKL 150 Score = 53.9 bits (128), Expect = 4e-07 Identities = 32/101 (31%), Positives = 57/101 (56%) Frame = -1 Query: 525 KKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGY 346 +K L G++ + +D G+ L ++ +G + + LLE GA V+ + TPL A+ Y Sbjct: 82 EKLLSKGSNVNTKDFSGKTPLMWSIIFGYSEMSYFLLEHGANVNDRNLEGETPLIVASKY 141 Query: 345 GRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKL 223 GR E V LL+ GA ++ +++ G T A++ + EV+K+ Sbjct: 142 GRSEIVKKLLELGADISARDLTGLTAEASARIFGRQEVIKI 182
>V231_FOWPV (Q9J504) Putative ankyrin repeat protein FPV231| Length = 256 Score = 58.2 bits (139), Expect = 2e-08 Identities = 33/102 (32%), Positives = 56/102 (54%) Frame = -1 Query: 570 SIVHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDA 391 S++H + +K L+ G D + D+ G ALH+A + ++LL +GA + Sbjct: 60 SVLHKAIGNNNITSVKLLLNHGIDYNLRDNHGYTALHYAITLQNREITDMLLSSGADPNI 119 Query: 390 MDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPI 265 M+ K+TPL++A Y R V+ L+ HGA + + + GKTP+ Sbjct: 120 MNNEKHTPLYHALLY-RSSNVESLILHGADINIVDDTGKTPL 160 Score = 52.0 bits (123), Expect = 2e-06 Identities = 34/115 (29%), Positives = 49/115 (42%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMD 385 ++H + + E L GAD + D R LH A G ++LL G + D Sbjct: 29 LNHAIATNNKELTSLFLARGADTNIVDKYNRSVLHKAIGNNNITSVKLLLNHGIDYNLRD 88 Query: 384 KNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 + T LHYA +E D+LL GA + N + TP+ A L V L+ Sbjct: 89 NHGYTALHYAITLQNREITDMLLSSGADPNIMNNEKHTPLYHALLYRSSNVESLI 143 Score = 42.0 bits (97), Expect = 0.002 Identities = 30/102 (29%), Positives = 42/102 (41%) Frame = -1 Query: 525 KKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGY 346 K LD GA D + E L+ A + + L GA + +DK + LH A G Sbjct: 9 KMLLDYGARIDSRNKEECLPLNHAIATNNKELTSLFLARGADTNIVDKYNRSVLHKAIGN 68 Query: 345 GRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 V LLL HG L++ G T + A E+ +L Sbjct: 69 NNITSVKLLLNHGIDYNLRDNHGYTALHYAITLQNREITDML 110 Score = 39.3 bits (90), Expect = 0.011 Identities = 22/76 (28%), Positives = 39/76 (51%) Frame = -1 Query: 447 YGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTP 268 +G +++LL+ GA +D+ +K + PL++A KE L L GA + + ++ Sbjct: 2 FGNTTISKMLLDYGARIDSRNKEECLPLNHAIATNNKELTSLFLARGADTNIVDKYNRSV 61 Query: 267 IDVAKLNNQDEVLKLL 220 + A NN +KLL Sbjct: 62 LHKAIGNNNITSVKLL 77
>AKR1_ASHGO (Q755Y0) Palmitoyltransferase AKR1 (EC 2.3.1.-) (Ankyrin| repeat-containing protein AKR1) Length = 724 Score = 58.2 bits (139), Expect = 2e-08 Identities = 32/90 (35%), Positives = 48/90 (53%) Frame = -1 Query: 495 DEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLL 316 D D G+ ALH+A G+ E LL+ A V +D TPLH+A G + L+ Sbjct: 186 DSPDPTGKTALHWAAYQGDPNTVEALLKFDADVRVVDTGGFTPLHWATVKGHPHVLKALI 245 Query: 315 KHGAAVTLQNMDGKTPIDVAKLNNQDEVLK 226 +HG+ V L+N DGK + +A+ N + L+ Sbjct: 246 EHGSDVFLKNNDGKNALMIAQEMNTQKALQ 275 Score = 47.0 bits (110), Expect = 5e-05 Identities = 38/109 (34%), Positives = 49/109 (44%), Gaps = 4/109 (3%) Frame = -1 Query: 516 LDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAA-VDAMDKNKNTPLHYAAGYGR 340 L+ GAD D +G LH + E +L G VD+ D T LH+AA G Sbjct: 145 LEHGADPLITDRQGYNLLHTSTFSSEVMLITYVLFTGQIPVDSPDPTGKTALHWAAYQGD 204 Query: 339 KECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL---EKDVFL 202 V+ LLK A V + + G TP+ A + VLK L DVFL Sbjct: 205 PNTVEALLKFDADVRVVDTGGFTPLHWATVKGHPHVLKALIEHGSDVFL 253 Score = 38.1 bits (87), Expect = 0.024 Identities = 30/101 (29%), Positives = 45/101 (44%), Gaps = 6/101 (5%) Frame = -1 Query: 561 HHTASVGDGEGLKKALDGG-----ADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAV 397 H GD + +K ++ G AD DEE+ LH+A L+ GA V Sbjct: 60 HAACQRGDLKTVKDMIEAGVIDVKADWDEEEQVS--GLHWASANNRLNLVRYLIAQGADV 117 Query: 396 DAMDKN-KNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDG 277 + + + TPLH+A+ G V LL+HGA + + G Sbjct: 118 NIKGGDLEATPLHWASKSGYVYIVHCLLEHGADPLITDRQG 158
>ASB5_MOUSE (Q9D1A4) Ankyrin repeat and SOCS box protein 5 (ASB-5)| Length = 329 Score = 58.2 bits (139), Expect = 2e-08 Identities = 47/139 (33%), Positives = 62/139 (44%) Frame = -1 Query: 639 GTVSTAEPSXXXXXXXXXXXXXESIVHHTASVGDGEGLKKALDGGADKDEEDSEGRRALH 460 G+ S AE S H AS G E L + G D D++ L+ Sbjct: 147 GSASCAELLLEYGAKAQLESCFPSPTHEAASKGHHECLDILIAWGIDVDQDIPHLGTPLY 206 Query: 459 FACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMD 280 AC +F C LL AGA V K +TPLH AA E V+LLL+ GA + +N D Sbjct: 207 VACMSQQFHCIWKLLYAGADVHK-GKYWDTPLHAAAQQPSTEIVNLLLEFGADINAKNTD 265 Query: 279 GKTPIDVAKLNNQDEVLKL 223 P+D+A N+ E + L Sbjct: 266 LLRPVDLATSNSAVERILL 284 Score = 50.8 bits (120), Expect = 4e-06 Identities = 33/95 (34%), Positives = 46/95 (48%) Frame = -1 Query: 570 SIVHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDA 391 S +H AS G L+ L G + + + LH AC CA LLEAGA +A Sbjct: 72 SPLHEAASQGRLLALRTLLSQGYNVNAVTIDHVTPLHEACLGDHVACARTLLEAGANANA 131 Query: 390 MDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQN 286 + + TPL A G C +LLL++GA L++ Sbjct: 132 ITIDGVTPLFNACSQGSASCAELLLEYGAKAQLES 166 Score = 40.0 bits (92), Expect = 0.006 Identities = 45/173 (26%), Positives = 62/173 (35%), Gaps = 6/173 (3%) Frame = -1 Query: 507 GADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECV 328 G + + R LH A G LL G V+A+ + TPLH A C Sbjct: 60 GVSQGQGSWADRSPLHEAASQGRLLALRTLLSQGYNVNAVTIDHVTPLHEACLGDHVACA 119 Query: 327 DLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLLEKDVFL*IASLGSHEETWPSSCFT 148 LL+ GA +DG TP+ A +LL L + SCF Sbjct: 120 RTLLEAGANANAITIDGVTPLFNACSQGSASCAELL----------LEYGAKAQLESCFP 169 Query: 147 SLWHWLDSHTRIGILFVV*EYTTCVSWPAGRL-AEVRTAC-----YCIWRLVY 7 S H S L ++ + V L + AC +CIW+L+Y Sbjct: 170 SPTHEAASKGHHECLDILIAWGIDVDQDIPHLGTPLYVACMSQQFHCIWKLLY 222
>MIB2_RAT (Q68LP1) Ubiquitin ligase protein MIB2 (EC 6.3.2.-) (Mind bomb| homolog 2) (RBSC-skeletrophin/dystrophin-like polypeptide) Length = 971 Score = 57.8 bits (138), Expect = 3e-08 Identities = 34/88 (38%), Positives = 47/88 (53%) Frame = -1 Query: 483 SEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLLKHGA 304 ++GR AL A G+ + +LL+A A+VD +D+ NT LHY A + E LLL G Sbjct: 477 NQGRTALQVAAYLGQVELVRLLLQARASVDLLDEEGNTALHYTAMGNQPEATRLLLSAGC 536 Query: 303 AVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 V QN T + VA EV+K+L Sbjct: 537 GVDAQNGTRSTALHVAVQRGFLEVVKIL 564 Score = 57.0 bits (136), Expect = 5e-08 Identities = 34/99 (34%), Positives = 48/99 (48%) Frame = -1 Query: 552 ASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKN 373 A +G E ++ L A D D EG ALH+ + + +LL AG VDA + ++ Sbjct: 487 AYLGQVELVRLLLQARASVDLLDEEGNTALHYTAMGNQPEATRLLLSAGCGVDAQNGTRS 546 Query: 372 TPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVA 256 T LH A G E V +L +HG V L + TP+ A Sbjct: 547 TALHVAVQRGFLEVVKILCEHGCDVNLPDAHADTPLHSA 585 Score = 48.9 bits (115), Expect = 1e-05 Identities = 36/108 (33%), Positives = 50/108 (46%), Gaps = 3/108 (2%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMD 385 +H+TA E + L G D ++ ALH A G + +IL E G V+ D Sbjct: 516 LHYTAMGNQPEATRLLLSAGCGVDAQNGTRSTALHVAVQRGFLEVVKILCEHGCDVNLPD 575 Query: 384 KNKNTPLHYA--AGYGRKECVDLLLK-HGAAVTLQNMDGKTPIDVAKL 250 + +TPLH A AG G V++L + G VT N G T + A L Sbjct: 576 AHADTPLHSAISAGAGASSIVEVLTEVPGIDVTATNSQGFTLLHHASL 623
>PA2G6_MOUSE (P97819) 85 kDa calcium-independent phospholipase A2 (EC 3.1.1.4)| (iPLA2) (CaI-PLA2) (Group VI phospholipase A2) (GVI PLA2) Length = 752 Score = 57.8 bits (138), Expect = 3e-08 Identities = 37/101 (36%), Positives = 47/101 (46%), Gaps = 1/101 (0%) Frame = -1 Query: 540 DGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLH 361 + E + L G D D S G ALH A F C +LL GA A ++ NTPLH Sbjct: 296 NAEMARMLLKRGCDVDSTSSSGNTALHVAVMRNRFDCVMVLLTYGANAGARGEHGNTPLH 355 Query: 360 YAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVA-KLNNQ 241 A E V L+ GA V N G+TP +A K++ Q Sbjct: 356 LAMSKDNMEMVKALIVFGAEVDTPNDFGETPALIASKISKQ 396 Score = 48.1 bits (113), Expect = 2e-05 Identities = 34/116 (29%), Positives = 55/116 (47%), Gaps = 3/116 (2%) Frame = -1 Query: 558 HTASVGDGEGLKK---ALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAM 388 HTA +G + ++D ++ G LH+A + A +LL+ G VD+ Sbjct: 257 HTAMKFSQKGCAEMIISMDSNQIHSKDPRYGASPLHWA---KNAEMARMLLKRGCDVDST 313 Query: 387 DKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 + NT LH A R +CV +LL +GA + G TP+ +A + E++K L Sbjct: 314 SSSGNTALHVAVMRNRFDCVMVLLTYGANAGARGEHGNTPLHLAMSKDNMEMVKAL 369
>ASB3_HUMAN (Q9Y575) Ankyrin repeat and SOCS box protein 3 (ASB-3)| Length = 518 Score = 57.8 bits (138), Expect = 3e-08 Identities = 41/117 (35%), Positives = 59/117 (50%), Gaps = 2/117 (1%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMD 385 +H + + E +K L GA+K+ +D G L A YG+ + IL+ +GA V+ Sbjct: 150 LHQASFQENAEIIKLLLRKGANKECQDDFGITPLFVAAQYGKLESLSILISSGANVNCQA 209 Query: 384 KNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQ-NMDG-KTPIDVAKLNNQDEVLKLL 220 +K TPL AA G +CV+LLL GA L N D + PI A ++L LL Sbjct: 210 LDKATPLFIAAQEGHTKCVELLLSSGADPDLYCNEDSWQLPIHAAAQMGHTKILDLL 266 Score = 55.5 bits (132), Expect = 1e-07 Identities = 35/88 (39%), Positives = 47/88 (53%), Gaps = 1/88 (1%) Frame = -1 Query: 480 EGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLLKHGAA 301 EG ALH A G +K +ILLEAGA +A + TPL A G+ + + LLL+HGA Sbjct: 78 EGFCALHLAASQGHWKIVQILLEAGADPNATTLEETTPLFLAVENGQIDVLRLLLQHGAN 137 Query: 300 VT-LQNMDGKTPIDVAKLNNQDEVLKLL 220 V +M G + A E++KLL Sbjct: 138 VNGSHSMCGWNSLHQASFQENAEIIKLL 165 Score = 48.1 bits (113), Expect = 2e-05 Identities = 34/109 (31%), Positives = 53/109 (48%), Gaps = 1/109 (0%) Frame = -1 Query: 543 GDGEGLKKALDGGADKDEEDSE-GRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTP 367 G + L+ L GA+ + S G +LH A + ++LL GA + D TP Sbjct: 123 GQIDVLRLLLQHGANVNGSHSMCGWNSLHQASFQENAEIIKLLLRKGANKECQDDFGITP 182 Query: 366 LHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 L AA YG+ E + +L+ GA V Q +D TP+ +A + ++LL Sbjct: 183 LFVAAQYGKLESLSILISSGANVNCQALDKATPLFIAAQEGHTKCVELL 231 Score = 40.0 bits (92), Expect = 0.006 Identities = 29/113 (25%), Positives = 50/113 (44%), Gaps = 2/113 (1%) Frame = -1 Query: 552 ASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAM--DKN 379 A G E L + GA+ + + + L A G KC E+LL +GA D + + Sbjct: 187 AQYGKLESLSILISSGANVNCQALDKATPLFIAAQEGHTKCVELLLSSGADPDLYCNEDS 246 Query: 378 KNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 P+H AA G + +DLL+ ++ +P+ A ++ L++L Sbjct: 247 WQLPIHAAAQMGHTKILDLLIPLTNRACDTGLNKVSPVYSAVFGGHEDCLEIL 299 Score = 32.7 bits (73), Expect = 1.0 Identities = 18/78 (23%), Positives = 38/78 (48%), Gaps = 3/78 (3%) Frame = -1 Query: 444 GEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLLKHGAA---VTLQNMDGK 274 G K LL+ G +VD D P+H AA + EC+ +L+ ++ + ++ +G Sbjct: 21 GNVKVLRKLLKKGRSVDVADNRGWMPIHEAAYHNSVECLQMLINADSSENYIKMKTFEGF 80 Query: 273 TPIDVAKLNNQDEVLKLL 220 + +A +++++L Sbjct: 81 CALHLAASQGHWKIVQIL 98
>ASB5_RABIT (Q862Z2) Ankyrin repeat and SOCS box protein 5 (ASB-5)| Length = 329 Score = 57.8 bits (138), Expect = 3e-08 Identities = 41/116 (35%), Positives = 57/116 (49%) Frame = -1 Query: 570 SIVHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDA 391 S H AS G E L + G D D++ L+ AC +F C LL AGA V Sbjct: 170 SPTHEAASKGHHEFLDLLISWGIDVDQDIPHLGTPLYVACMSQQFHCIWKLLYAGADVQK 229 Query: 390 MDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKL 223 K +TPLH AA E V+LL++ GA + +N + P+DVA ++ E + L Sbjct: 230 -GKYWDTPLHAAAQQSSTEIVNLLIEFGADINAKNTELLRPVDVATTSSMVERILL 284 Score = 52.8 bits (125), Expect = 9e-07 Identities = 40/117 (34%), Positives = 54/117 (46%) Frame = -1 Query: 570 SIVHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDA 391 S +H AS G L+ L G + + + LH AC CA LLEAGA V+A Sbjct: 72 SPLHEAASQGRLLALRTLLSQGYNVNAVTIDHITPLHEACLGDHVACARTLLEAGANVNA 131 Query: 390 MDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 + + TPL A G C +LLL++GA L++ +P A E L LL Sbjct: 132 ITIDGVTPLFNACSQGSTSCTELLLEYGAKAQLESC-LPSPTHEAASKGHHEFLDLL 187 Score = 39.3 bits (90), Expect = 0.011 Identities = 25/70 (35%), Positives = 31/70 (44%) Frame = -1 Query: 474 RRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLLKHGAAVT 295 R LH A G LL G V+A+ + TPLH A C LL+ GA V Sbjct: 71 RSPLHEAASQGRLLALRTLLSQGYNVNAVTIDHITPLHEACLGDHVACARTLLEAGANVN 130 Query: 294 LQNMDGKTPI 265 +DG TP+ Sbjct: 131 AITIDGVTPL 140
>AKR1_CRYNE (Q5KP49) Palmitoyltransferase AKR1 (EC 2.3.1.-) (Ankyrin| repeat-containing protein AKR1) Length = 776 Score = 57.4 bits (137), Expect = 4e-08 Identities = 30/81 (37%), Positives = 50/81 (61%) Frame = -1 Query: 495 DEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLL 316 DE+D++G AL +A G+ ++L+ GA+V++ D TPLH+AA G K + L+ Sbjct: 198 DEKDTDGHTALMWAAYQGDALSVDLLIRHGASVNSTDNAGMTPLHWAAVKGNKVSIMHLV 257 Query: 315 KHGAAVTLQNMDGKTPIDVAK 253 + GA++ + GKTP D+A+ Sbjct: 258 EAGASLDAKEEAGKTPRDMAE 278 Score = 50.8 bits (120), Expect = 4e-06 Identities = 37/113 (32%), Positives = 55/113 (48%), Gaps = 1/113 (0%) Frame = -1 Query: 507 GADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECV 328 GAD + DS+G LH +L A+D D + +T L +AA G V Sbjct: 161 GADPNIHDSQGFNTLHLITHSSAVMPLLYMLHQPVAIDEKDTDGHTALMWAAYQGDALSV 220 Query: 327 DLLLKHGAAVTLQNMDGKTPIDVAKL-NNQDEVLKLLEKDVFL*IASLGSHEE 172 DLL++HGA+V + G TP+ A + N+ ++ L+E ASL + EE Sbjct: 221 DLLIRHGASVNSTDNAGMTPLHWAAVKGNKVSIMHLVEAG-----ASLDAKEE 268 Score = 37.7 bits (86), Expect = 0.031 Identities = 27/99 (27%), Positives = 45/99 (45%), Gaps = 3/99 (3%) Frame = -1 Query: 564 VHHTASVGDGEGLKKAL--DGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDA 391 +H A GD + L + + D++ LH+A +L+++GA +DA Sbjct: 73 IHALAQRGDTAAIAAMLQENPSLNLSARDAQDVTPLHWAAINAHMGTCRLLIDSGADIDA 132 Query: 390 M-DKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDG 277 + + K TPL +AA G V LL+ GA + + G Sbjct: 133 IGGELKATPLQWAARNGHLYVVHLLISRGADPNIHDSQG 171 Score = 32.7 bits (73), Expect = 1.0 Identities = 19/59 (32%), Positives = 29/59 (49%) Frame = -1 Query: 543 GDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTP 367 GD + + GA + D+ G LH+A G L+EAGA++DA ++ TP Sbjct: 215 GDALSVDLLIRHGASVNSTDNAGMTPLHWAAVKGNKVSIMHLVEAGASLDAKEEAGKTP 273
>PA2G6_RAT (P97570) 85 kDa calcium-independent phospholipase A2 (EC 3.1.1.4)| (iPLA2) (CaI-PLA2) (Group VI phospholipase A2) (GVI PLA2) Length = 751 Score = 57.4 bits (137), Expect = 4e-08 Identities = 36/101 (35%), Positives = 47/101 (46%), Gaps = 1/101 (0%) Frame = -1 Query: 540 DGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLH 361 + E + L G D D + G ALH A F C +LL GA A ++ NTPLH Sbjct: 295 NAEMARMLLKRGCDVDSTSASGNTALHVAVTRNRFDCVMVLLTYGANAGARGEHGNTPLH 354 Query: 360 YAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVA-KLNNQ 241 A E V L+ GA V N G+TP +A K++ Q Sbjct: 355 LAMSKDNMEMVKALIVFGAEVDTPNDFGETPAFIASKISKQ 395 Score = 48.1 bits (113), Expect = 2e-05 Identities = 34/116 (29%), Positives = 55/116 (47%), Gaps = 3/116 (2%) Frame = -1 Query: 558 HTASVGDGEGLKK---ALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAM 388 HTA +G + ++D ++ G LH+A + A +LL+ G VD+ Sbjct: 256 HTAMKFSQKGCAEMIISMDSNQIHSKDPRYGASPLHWA---KNAEMARMLLKRGCDVDST 312 Query: 387 DKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 + NT LH A R +CV +LL +GA + G TP+ +A + E++K L Sbjct: 313 SASGNTALHVAVTRNRFDCVMVLLTYGANAGARGEHGNTPLHLAMSKDNMEMVKAL 368
>V218_FOWPV (Q9J517) Putative ankyrin repeat protein FPV218| Length = 461 Score = 57.0 bits (136), Expect = 5e-08 Identities = 36/117 (30%), Positives = 61/117 (52%) Frame = -1 Query: 570 SIVHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDA 391 S +H+ A D + + + GA+ + +DS+G LH A A+ILLE GA V+ Sbjct: 123 SFLHYAAKNDDVDTVISLILHGANVNVQDSKGLSPLHHAVSKKTTLTAKILLENGARVNI 182 Query: 390 MDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 D PLH G E V LL+ +G+ + +++++G TP+ A + + ++LL Sbjct: 183 RDSLGRLPLH--LGANTYEMVKLLIDYGSPIDIKDVNGSTPLHYAIWKSSLDTIRLL 237 Score = 52.4 bits (124), Expect = 1e-06 Identities = 30/92 (32%), Positives = 52/92 (56%) Frame = -1 Query: 534 EGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYA 355 E +K +D G+ D +D G LH+A +L+ + ++A+D N N+PLHY Sbjct: 199 EMVKLLIDYGSPIDIKDVNGSTPLHYAIWKSSLDTIRLLVNV-STINALDNNCNSPLHYI 257 Query: 354 AGYGRKECVDLLLKHGAAVTLQNMDGKTPIDV 259 + V+LLL+ GA +T++++ G TP+D+ Sbjct: 258 ILSETEILVELLLR-GADITIKDICGNTPLDI 288 Score = 49.3 bits (116), Expect = 1e-05 Identities = 34/117 (29%), Positives = 57/117 (48%) Frame = -1 Query: 570 SIVHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDA 391 S +HH S K L+ GA + DS GR LH G ++ ++L++ G+ +D Sbjct: 156 SPLHHAVSKKTTLTAKILLENGARVNIRDSLGRLPLHL--GANTYEMVKLLIDYGSPIDI 213 Query: 390 MDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 D N +TPLHYA + + LL+ L N + +P+ L+ + +++LL Sbjct: 214 KDVNGSTPLHYAIWKSSLDTIRLLVNVSTINALDN-NCNSPLHYIILSETEILVELL 269 Score = 44.3 bits (103), Expect = 3e-04 Identities = 29/96 (30%), Positives = 47/96 (48%) Frame = -1 Query: 507 GADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECV 328 G D + D E R LH+A + L+ GA V+ D +PLH+A Sbjct: 111 GIDVNVIDRESRSFLHYAAKNDDVDTVISLILHGANVNVQDSKGLSPLHHAVSKKTTLTA 170 Query: 327 DLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 +LL++GA V +++ G+ P+ + N E++KLL Sbjct: 171 KILLENGARVNIRDSLGRLPLHLGA--NTYEMVKLL 204 Score = 38.5 bits (88), Expect = 0.018 Identities = 23/76 (30%), Positives = 37/76 (48%) Frame = -1 Query: 447 YGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTP 268 Y F ++L+ G V+ +D+ + LHYAA + V L+ HGA V +Q+ G +P Sbjct: 98 YVSFPIIKVLVYHGIDVNVIDRESRSFLHYAAKNDDVDTVISLILHGANVNVQDSKGLSP 157 Query: 267 IDVAKLNNQDEVLKLL 220 + A K+L Sbjct: 158 LHHAVSKKTTLTAKIL 173
>V162_FOWPV (Q9J569) Putative ankyrin repeat protein FPV162| Length = 603 Score = 57.0 bits (136), Expect = 5e-08 Identities = 38/112 (33%), Positives = 58/112 (51%), Gaps = 3/112 (2%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGY--GEFKCAEILLEAGAAVDA 391 +H+ E KK LD GAD + + G+ LH A + IL+E GA V+A Sbjct: 96 LHYAVQENGLEATKKLLDLGADPNTKYMNGQTPLHCAAMVIPDGPELVRILVEYGANVNA 155 Query: 390 MDKNKNTPLHYAAGYGR-KECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQD 238 +D NTPL AA + ++ L++ GA V ++N DG TP+ +A ++ D Sbjct: 156 LDNKHNTPLALAAELSNTNKTIETLIELGADVKIKNNDGITPLHLAAKSSSD 207 Score = 48.9 bits (115), Expect = 1e-05 Identities = 35/106 (33%), Positives = 54/106 (50%), Gaps = 3/106 (2%) Frame = -1 Query: 528 LKKALDGGADKDEEDSEGRRALHFAC-GYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAA 352 ++ ++ GAD ++++G LH A + K E L+ GA V+A NTPLH AA Sbjct: 177 IETLIELGADVKIKNNDGITPLHLAAKSSSDSKTVETLILHGADVNATCSEGNTPLHDAA 236 Query: 351 -GYGRKECVDLLLKHGAAVTLQNMDGKTPID-VAKLNNQDEVLKLL 220 Y +++L+++GA V N G TP+ A+ N LK L Sbjct: 237 TSYELSNTIEMLIEYGAEVNAANSVGDTPLHCAARSRNPVHKLKTL 282 Score = 47.4 bits (111), Expect = 4e-05 Identities = 27/74 (36%), Positives = 45/74 (60%), Gaps = 4/74 (5%) Frame = -1 Query: 426 EILLEAGAAVDAMDKNKNTPLHYAA----GYGRKECVDLLLKHGAAVTLQNMDGKTPIDV 259 ++L+E GA V+++D TP+HY + K V+LL++HGA + +N+ G TP+ Sbjct: 314 KVLIEHGAEVNSVDIYGRTPMHYISRSYSSQSLKTAVELLVEHGADIEAKNVIGGTPLSS 373 Query: 258 AKLNNQDEVLKLLE 217 A NN + L+L+E Sbjct: 374 A-CNNIEYDLRLIE 386 Score = 40.4 bits (93), Expect = 0.005 Identities = 31/108 (28%), Positives = 52/108 (48%), Gaps = 3/108 (2%) Frame = -1 Query: 534 EGLKKALDGGADKDEEDSEGRRALHFACG-YGEFKCAEILLEAGAAVDAMDKNKNTPLHY 358 E ++ + GAD + + ALH+A + + L+ G V+ D ++TPLHY Sbjct: 39 ERIRMFVSKGADINVISDFKKTALHYAAKKLATPEVLKTLIYLGTNVNVTDMFESTPLHY 98 Query: 357 AAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQD--EVLKLL 220 A E LL GA + M+G+TP+ A + D E++++L Sbjct: 99 AVQENGLEATKKLLDLGADPNTKYMNGQTPLHCAAMVIPDGPELVRIL 146 Score = 38.1 bits (87), Expect = 0.024 Identities = 37/144 (25%), Positives = 58/144 (40%), Gaps = 36/144 (25%) Frame = -1 Query: 549 SVGDGEGLKKALDGGADKDEEDSEGRRALHFAC-GYGEFKCAEILLEAGAAVDAMDKNKN 373 S D + ++ + GAD + SEG LH A Y E+L+E GA V+A + + Sbjct: 204 SSSDSKTVETLILHGADVNATCSEGNTPLHDAATSYELSNTIEMLIEYGAEVNAANSVGD 263 Query: 372 TPLHYAA-------------GYGRK----------------------ECVDLLLKHGAAV 298 TPLH AA +G E + +L++HGA V Sbjct: 264 TPLHCAARSRNPVHKLKTLIAHGSNVNAVNGISVTPLHLATYSDNATEALKVLIEHGAEV 323 Query: 297 TLQNMDGKTPIDVAKLNNQDEVLK 226 ++ G+TP+ + + LK Sbjct: 324 NSVDIYGRTPMHYISRSYSSQSLK 347 Score = 37.4 bits (85), Expect = 0.041 Identities = 35/145 (24%), Positives = 55/145 (37%), Gaps = 41/145 (28%) Frame = -1 Query: 558 HTASVGDG--EGLKKALDGGADKDEEDSEGRRALHF------------------------ 457 H A+ D E LK ++ GA+ + D GR +H+ Sbjct: 301 HLATYSDNATEALKVLIEHGAEVNSVDIYGRTPMHYISRSYSSQSLKTAVELLVEHGADI 360 Query: 456 -------------ACGYGEF--KCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDL 322 AC E+ + E +E GA ++ D TPL+ A Y E V+L Sbjct: 361 EAKNVIGGTPLSSACNNIEYDLRLIECFIEYGADINTRDIRDETPLYSAIKY--PEIVNL 418 Query: 321 LLKHGAAVTLQNMDGKTPIDVAKLN 247 L+ + A+ + N TP++ A N Sbjct: 419 LMNYSASTNITNKSNITPLESAIAN 443
>FANK1_HUMAN (Q8TC84) Fibronectin type 3 and ankyrin repeat domains protein 1| Length = 345 Score = 57.0 bits (136), Expect = 5e-08 Identities = 36/98 (36%), Positives = 53/98 (54%), Gaps = 2/98 (2%) Frame = -1 Query: 507 GADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKN-TPL-HYAAGYGRKE 334 GA D G ALH+A G E +++ G VD +D TPL +A G + Sbjct: 200 GASWQARDLGGCTALHWAADGGHCSVIEWMIKDGCEVDVVDTGSGWTPLMRVSAVSGNQR 259 Query: 333 CVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 LL+ GA V +++ +GKTP+ VA LNN +E+++LL Sbjct: 260 VASLLIDAGANVNVKDRNGKTPLMVAVLNNHEELVQLL 297 Score = 52.8 bits (125), Expect = 9e-07 Identities = 28/77 (36%), Positives = 47/77 (61%) Frame = -1 Query: 444 GEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPI 265 G + A +L++AGA V+ D+N TPL A +E V LLL GA +++N GK + Sbjct: 256 GNQRVASLLIDAGANVNVKDRNGKTPLMVAVLNNHEELVQLLLDKGADASVKNEFGKGVL 315 Query: 264 DVAKLNNQDEVLKLLEK 214 ++A++ ++ V+ LLE+ Sbjct: 316 EMARVFDRQSVVSLLEE 332
>PYX_DROME (Q9W0T5) Transient receptor potential channel pyrexia| Length = 956 Score = 56.6 bits (135), Expect = 6e-08 Identities = 36/88 (40%), Positives = 46/88 (52%), Gaps = 1/88 (1%) Frame = -1 Query: 480 EGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLLKHGAA 301 E R ALH+A C EILL+ GA + TPLH A+ G +CV LLL H A Sbjct: 198 EKRSALHYAIDVNAVDCVEILLKYGADPNTPQVYTETPLHTASAAGFAKCVQLLLSHNAD 257 Query: 300 VTLQNMDGK-TPIDVAKLNNQDEVLKLL 220 V Q +GK T + +A N+ E +LL Sbjct: 258 VRSQFGEGKVTALHLAAENDYVECARLL 285 Score = 53.9 bits (128), Expect = 4e-07 Identities = 38/103 (36%), Positives = 51/103 (49%), Gaps = 2/103 (1%) Frame = -1 Query: 558 HTASV-GDGEGLKKALDGGADKDEEDSEGR-RALHFACGYGEFKCAEILLEAGAAVDAMD 385 HTAS G + ++ L AD + EG+ ALH A +CA +LLE A VD + Sbjct: 237 HTASAAGFAKCVQLLLSHNADVRSQFGEGKVTALHLAAENDYVECARLLLEHRAEVDCRN 296 Query: 384 KNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVA 256 + TPLH A VDLL+ +GA V DG+T + A Sbjct: 297 ASHQTPLHLACLSQSIGTVDLLISYGANVNAVYRDGRTALHAA 339 Score = 52.4 bits (124), Expect = 1e-06 Identities = 38/118 (32%), Positives = 55/118 (46%), Gaps = 1/118 (0%) Frame = -1 Query: 570 SIVHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDA 391 S +H+ V + ++ L GAD + LH A G KC ++LL A V + Sbjct: 201 SALHYAIDVNAVDCVEILLKYGADPNTPQVYTETPLHTASAAGFAKCVQLLLSHNADVRS 260 Query: 390 M-DKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 + K T LH AA EC LLL+H A V +N +TP+ +A L+ + LL Sbjct: 261 QFGEGKVTALHLAAENDYVECARLLLEHRAEVDCRNASHQTPLHLACLSQSIGTVDLL 318 Score = 49.7 bits (117), Expect = 8e-06 Identities = 29/72 (40%), Positives = 39/72 (54%), Gaps = 1/72 (1%) Frame = -1 Query: 504 ADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKN-TPLHYAAGYGRKECV 328 AD + DS GR LHFAC A++LL+ GA + D K T LH AA EC+ Sbjct: 124 ADPNVADSRGRTPLHFACCRANAPIAKVLLDFGADPNRWDARKEVTSLHCAASSKSVECI 183 Query: 327 DLLLKHGAAVTL 292 LLL+ A++ + Sbjct: 184 LLLLRRKASINI 195 Score = 44.7 bits (104), Expect = 3e-04 Identities = 31/100 (31%), Positives = 46/100 (46%), Gaps = 2/100 (2%) Frame = -1 Query: 507 GADKDEEDSEGRRALHFAC--GYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKE 334 GA+ + +GR ALH A C LL+AGA V+ D TPLH AA Sbjct: 322 GANVNAVYRDGRTALHAAIVKQSRSLDCCNALLKAGADVNKADNYGYTPLHIAALNEFSS 381 Query: 333 CVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLLEK 214 CV ++HGA +T + + + + + KL++K Sbjct: 382 CVYTFIEHGADITARTDGRVSALSFIVRRTPEIIPKLMQK 421
>ANR10_HUMAN (Q9NXR5) Ankyrin repeat domain-containing protein 10| Length = 420 Score = 56.2 bits (134), Expect = 8e-08 Identities = 37/116 (31%), Positives = 55/116 (47%), Gaps = 1/116 (0%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSE-GRRALHFACGYGEFKCAEILLEAGAAVDAM 388 VH A G E L + + GA + + + H A G +C L++AGA ++ Sbjct: 62 VHWAAHFGKLECLVQLVRAGATLNVSTTRYAQTPAHIAAFGGHPQCLVWLIQAGANINKP 121 Query: 387 DKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 D TP+H AA G EC+ L+ +GA V L+N G T D+A+ E + L Sbjct: 122 DCEGETPIHKAARSGSLECISALVANGAHVDLRNASGLTAADIAQTQGFQECAQSL 177 Score = 33.9 bits (76), Expect = 0.45 Identities = 28/112 (25%), Positives = 48/112 (42%), Gaps = 4/112 (3%) Frame = -1 Query: 552 ASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKN 373 ++ G G G++ EE R LH AC G+ LL+ ++ Sbjct: 2 SAAGAGAGVEAGFSS-----EELLSLRFPLHRACRDGDLATLCSLLQQTPHAHLASEDSF 56 Query: 372 ---TPLHYAAGYGRKECVDLLLKHGAAVTLQNMD-GKTPIDVAKLNNQDEVL 229 TP+H+AA +G+ EC+ L++ GA + + +TP +A + L Sbjct: 57 YGWTPVHWAAHFGKLECLVQLVRAGATLNVSTTRYAQTPAHIAAFGGHPQCL 108
>ASB9_MOUSE (Q91ZT8) Ankyrin repeat and SOCS box protein 9 (ASB-9)| Length = 290 Score = 56.2 bits (134), Expect = 8e-08 Identities = 36/109 (33%), Positives = 54/109 (49%) Frame = -1 Query: 570 SIVHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDA 391 S +H A G + ++ GA+ D S L+ AC + CA+ LLE+G +V+ Sbjct: 132 SPIHEAAKRGYVKCIESLAAHGANIDYNISHLGTPLYVACKNQQVACAKKLLESGVSVN- 190 Query: 390 MDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNN 244 K ++PLH A E V LL+ GA +N DGK P+D+ L + Sbjct: 191 QGKGLDSPLHVVARMSSVELVHLLMDFGANAQAKNADGKRPVDLVPLES 239 Score = 51.6 bits (122), Expect = 2e-06 Identities = 26/54 (48%), Positives = 33/54 (61%) Frame = -1 Query: 465 LHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLLKHGA 304 LH AC G CA +LL GA V+ M + TPL A G ++CV+LLL+HGA Sbjct: 69 LHEACLRGHLSCASVLLSHGAQVNGMTIDWRTPLFNACVSGSQDCVNLLLQHGA 122 Score = 41.6 bits (96), Expect = 0.002 Identities = 25/82 (30%), Positives = 39/82 (47%) Frame = -1 Query: 465 LHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQN 286 LH A +G L+ G V+ + + +PLH A G C +LL HGA V Sbjct: 36 LHDAAIHGCLLTLRNLISQGWPVNIITADHVSPLHEACLRGHLSCASVLLSHGAQVNGMT 95 Query: 285 MDGKTPIDVAKLNNQDEVLKLL 220 +D +TP+ A ++ + + LL Sbjct: 96 IDWRTPLFNACVSGSQDCVNLL 117
>PA2G6_HUMAN (O60733) 85 kDa calcium-independent phospholipase A2 (EC 3.1.1.4)| (iPLA2) (CaI-PLA2) (Group VI phospholipase A2) (GVI PLA2) Length = 806 Score = 56.2 bits (134), Expect = 8e-08 Identities = 37/111 (33%), Positives = 51/111 (45%), Gaps = 4/111 (3%) Frame = -1 Query: 540 DGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLH 361 + E + L G + + S G ALH A F CA +LL GA DA ++ NTPLH Sbjct: 296 NAEMARMLLKRGCNVNSTSSAGNTALHVAVMRNRFDCAIVLLTHGANADARGEHGNTPLH 355 Query: 360 YAAGYGRKECVDLLLKHGAAVTLQNMDGKTPI----DVAKLNNQDEVLKLL 220 A E + L+ GA V N G+TP + +L + +L LL Sbjct: 356 LAMSKDNVEMIKALIVFGAEVDTPNDFGETPTFLASKIGRLVTRKAILTLL 406
>GORK_ARATH (Q94A76) Potassium channel GORK (Guard cell outward rectifying K(+)| channel) (AtGORK) Length = 820 Score = 55.8 bits (133), Expect = 1e-07 Identities = 31/79 (39%), Positives = 46/79 (58%) Frame = -1 Query: 555 TASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNK 376 T + GD + LK+ L G + + ED + R LH A G F A++L+EAGA+V + D+ Sbjct: 635 TVAKGDSDFLKRLLSSGMNPNSEDYDHRTPLHVAASEGLFLMAKMLVEAGASVISKDRWG 694 Query: 375 NTPLHYAAGYGRKECVDLL 319 N+PL A G K+ + LL Sbjct: 695 NSPLDEARLCGNKKLIKLL 713 Score = 54.7 bits (130), Expect = 2e-07 Identities = 38/115 (33%), Positives = 57/115 (49%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMD 385 V+ A GD LK + GAD ++ D +GR LH A G L++ G V+ D Sbjct: 535 VNSAAFQGDFYQLKSLIRSGADPNKTDYDGRSPLHLAACRGYEDITLFLIQEGVDVNLKD 594 Query: 384 KNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 K +TPL A G++ + LL+K GA+ L++ VAK + D + +LL Sbjct: 595 KFGHTPLFEAVKAGQEGVIGLLVKEGASFNLEDSGNFLCTTVAK-GDSDFLKRLL 648 Score = 45.8 bits (107), Expect = 1e-04 Identities = 32/97 (32%), Positives = 51/97 (52%) Frame = -1 Query: 507 GADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECV 328 GA + EDS A G +F + LL +G ++ D + TPLH AA G Sbjct: 620 GASFNLEDSGNFLCTTVAKGDSDF--LKRLLSSGMNPNSEDYDHRTPLHVAASEGLFLMA 677 Query: 327 DLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLLE 217 +L++ GA+V ++ G +P+D A+L +++KLLE Sbjct: 678 KMLVEAGASVISKDRWGNSPLDEARLCGNKKLIKLLE 714 Score = 43.1 bits (100), Expect = 7e-04 Identities = 27/94 (28%), Positives = 50/94 (53%) Frame = -1 Query: 492 EEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLLK 313 ++++E ++ A G+F + L+ +GA + D + +PLH AA G ++ L++ Sbjct: 526 KQEAELALKVNSAAFQGDFYQLKSLIRSGADPNKTDYDGRSPLHLAACRGYEDITLFLIQ 585 Query: 312 HGAAVTLQNMDGKTPIDVAKLNNQDEVLKLLEKD 211 G V L++ G TP+ A Q+ V+ LL K+ Sbjct: 586 EGVDVNLKDKFGHTPLFEAVKAGQEGVIGLLVKE 619
>ASZ1_PAPAN (Q8WMX7) Ankyrin repeat, SAM and basic leucine zipper| domain-containing protein 1 (Germ cell-specific ankyrin, SAM and basic leucine zipper domain-containing protein) Length = 475 Score = 55.5 bits (132), Expect = 1e-07 Identities = 39/119 (32%), Positives = 60/119 (50%), Gaps = 5/119 (4%) Frame = -1 Query: 558 HTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGE----FKCAEILLEAGAAVDA 391 + ASV + E ++ LD GA+ E + + +G KC E+LL A + Sbjct: 85 YAASVANAELVRVLLDRGANASFEKDKQTILITACSAHGSEEQILKCVELLLSRNADPNV 144 Query: 390 MDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPID-VAKLNNQDEVLKLLE 217 + TP+ YAA G + V LL+ HGA V Q+ +G T + A+ +++ VLKLLE Sbjct: 145 ACRRLMTPIMYAARDGHTQVVALLVAHGAEVNTQDENGYTALTWAARQGHKNIVLKLLE 203 Score = 53.1 bits (126), Expect = 7e-07 Identities = 31/80 (38%), Positives = 42/80 (52%) Frame = -1 Query: 459 FACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMD 280 +A G + +L+ GA V+ D+N T L +AA G K V LL+ GA LQ D Sbjct: 155 YAARDGHTQVVALLVAHGAEVNTQDENGYTALTWAARQGHKNIVLKLLELGANKMLQTKD 214 Query: 279 GKTPIDVAKLNNQDEVLKLL 220 GK P ++AK N E+ LL Sbjct: 215 GKMPSEIAKRNKHHEIFNLL 234 Score = 35.0 bits (79), Expect = 0.20 Identities = 24/78 (30%), Positives = 42/78 (53%), Gaps = 2/78 (2%) Frame = -1 Query: 444 GEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPI 265 G+ + LL++G +VD+ + TPL YAA E V +LL GA + + D +T + Sbjct: 57 GDVSLVQELLDSGISVDSTFQYGWTPLMYAASVANAELVRVLLDRGANASFEK-DKQTIL 115 Query: 264 DVA--KLNNQDEVLKLLE 217 A +++++LK +E Sbjct: 116 ITACSAHGSEEQILKCVE 133 Score = 32.7 bits (73), Expect = 1.0 Identities = 28/99 (28%), Positives = 42/99 (42%) Frame = -1 Query: 507 GADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECV 328 GA+ + +D G AL +A G LLE GA K+ P A E Sbjct: 172 GAEVNTQDENGYTALTWAARQGHKNIVLKLLELGANKMLQTKDGKMPSEIAKRNKHHEIF 231 Query: 327 DLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLLEKD 211 +LL + TL ++GK + +L +D + K+L D Sbjct: 232 NLL-----SFTLNPLEGK----LQQLTKEDTICKILTTD 261
>ASZ1_PANTR (Q8WMX6) Ankyrin repeat, SAM and basic leucine zipper| domain-containing protein 1 (Germ cell-specific ankyrin, SAM and basic leucine zipper domain-containing protein) Length = 475 Score = 55.5 bits (132), Expect = 1e-07 Identities = 39/119 (32%), Positives = 60/119 (50%), Gaps = 5/119 (4%) Frame = -1 Query: 558 HTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGE----FKCAEILLEAGAAVDA 391 + ASV + E ++ LD GA+ E + + +G KC E+LL A + Sbjct: 85 YAASVANAELVRVLLDRGANASFEKDKQSILITACSAHGSEEQILKCVELLLSRNADPNV 144 Query: 390 MDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPID-VAKLNNQDEVLKLLE 217 + TP+ YAA G + V LL+ HGA V Q+ +G T + A+ +++ VLKLLE Sbjct: 145 ACRRLMTPIMYAARDGHTQVVALLVAHGAEVNTQDENGYTALTWAARQGHKNIVLKLLE 203 Score = 53.1 bits (126), Expect = 7e-07 Identities = 31/80 (38%), Positives = 42/80 (52%) Frame = -1 Query: 459 FACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMD 280 +A G + +L+ GA V+ D+N T L +AA G K V LL+ GA LQ D Sbjct: 155 YAARDGHTQVVALLVAHGAEVNTQDENGYTALTWAARQGHKNIVLKLLELGANKMLQTKD 214 Query: 279 GKTPIDVAKLNNQDEVLKLL 220 GK P ++AK N E+ LL Sbjct: 215 GKMPSEIAKRNKHHEIFNLL 234 Score = 35.0 bits (79), Expect = 0.20 Identities = 22/77 (28%), Positives = 39/77 (50%), Gaps = 1/77 (1%) Frame = -1 Query: 444 GEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPI 265 G+ + LL++G +VD+ + TPL YAA E V +LL GA + + I Sbjct: 57 GDVSLVQELLDSGISVDSTFQYGWTPLMYAASVANAELVRVLLDRGANASFEKDKQSILI 116 Query: 264 DVAKLN-NQDEVLKLLE 217 + +++++LK +E Sbjct: 117 TACSAHGSEEQILKCVE 133 Score = 32.7 bits (73), Expect = 1.0 Identities = 28/99 (28%), Positives = 42/99 (42%) Frame = -1 Query: 507 GADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECV 328 GA+ + +D G AL +A G LLE GA K+ P A E Sbjct: 172 GAEVNTQDENGYTALTWAARQGHKNIVLKLLELGANKMLQTKDGKMPSEIAKRNKHHEIF 231 Query: 327 DLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLLEKD 211 +LL + TL ++GK + +L +D + K+L D Sbjct: 232 NLL-----SFTLNPLEGK----LQQLTKEDTICKILTTD 261
>ASZ1_HUMAN (Q8WWH4) Ankyrin repeat, SAM and basic leucine zipper| domain-containing protein 1 (Germ cell-specific ankyrin, SAM and basic leucine zipper domain-containing protein) Length = 475 Score = 55.5 bits (132), Expect = 1e-07 Identities = 39/119 (32%), Positives = 60/119 (50%), Gaps = 5/119 (4%) Frame = -1 Query: 558 HTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGE----FKCAEILLEAGAAVDA 391 + ASV + E ++ LD GA+ E + + +G KC E+LL A + Sbjct: 85 YAASVANAELVRVLLDRGANASFEKDKQSILITACSAHGSEEQILKCVELLLSRNADPNV 144 Query: 390 MDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPID-VAKLNNQDEVLKLLE 217 + TP+ YAA G + V LL+ HGA V Q+ +G T + A+ +++ VLKLLE Sbjct: 145 ACRRLMTPIMYAARDGHTQVVALLVAHGAEVNTQDENGYTALTWAARQGHKNIVLKLLE 203 Score = 53.1 bits (126), Expect = 7e-07 Identities = 31/80 (38%), Positives = 42/80 (52%) Frame = -1 Query: 459 FACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMD 280 +A G + +L+ GA V+ D+N T L +AA G K V LL+ GA LQ D Sbjct: 155 YAARDGHTQVVALLVAHGAEVNTQDENGYTALTWAARQGHKNIVLKLLELGANKMLQTKD 214 Query: 279 GKTPIDVAKLNNQDEVLKLL 220 GK P ++AK N E+ LL Sbjct: 215 GKMPSEIAKRNKHHEIFNLL 234 Score = 34.7 bits (78), Expect = 0.26 Identities = 22/77 (28%), Positives = 39/77 (50%), Gaps = 1/77 (1%) Frame = -1 Query: 444 GEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPI 265 G+ + LL++G +VD+ + TPL YAA E V +LL GA + + I Sbjct: 57 GDVSLVQELLDSGISVDSNFQYGWTPLMYAASVANAELVRVLLDRGANASFEKDKQSILI 116 Query: 264 DVAKLN-NQDEVLKLLE 217 + +++++LK +E Sbjct: 117 TACSAHGSEEQILKCVE 133 Score = 32.7 bits (73), Expect = 1.0 Identities = 28/99 (28%), Positives = 42/99 (42%) Frame = -1 Query: 507 GADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECV 328 GA+ + +D G AL +A G LLE GA K+ P A E Sbjct: 172 GAEVNTQDENGYTALTWAARQGHKNIVLKLLELGANKMLQTKDGKMPSEIAKRNKHHEIF 231 Query: 327 DLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLLEKD 211 +LL + TL ++GK + +L +D + K+L D Sbjct: 232 NLL-----SFTLNPLEGK----LQQLTKEDTICKILTTD 261
>LITA_LATMA (Q02989) Alpha-latroinsectotoxin precursor (Alpha-LIT) (Fragment)| Length = 1411 Score = 55.5 bits (132), Expect = 1e-07 Identities = 37/119 (31%), Positives = 61/119 (51%), Gaps = 1/119 (0%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMD 385 +H ++ G+ + + + L AD S+G ALH + L+E GA V+ Sbjct: 741 LHLASATGNKQLVIELLAKNADVTRLTSKGFSALHLGIIGKNEEIPFFLVEKGANVNDKT 800 Query: 384 KNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLK-LLEKD 211 + TPLH+AAG G+ LLL GA + ++++ + PI A N E+++ L+EKD Sbjct: 801 NSGVTPLHFAAGLGKANIFRLLLSRGADIKAEDINSQMPIHEAVSNGHLEIVRILIEKD 859 Score = 44.7 bits (104), Expect = 3e-04 Identities = 31/101 (30%), Positives = 49/101 (48%), Gaps = 2/101 (1%) Frame = -1 Query: 516 LDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGA-AVDAMDKNKNTPLHYAAGYGR 340 + GA+ E GR A+H A G + E+LL ++ DKN TPLH AA + Sbjct: 487 IQNGANVSETFELGRGAIHAAASAGNYDVGELLLNKDINLLEKADKNGYTPLHIAADSNK 546 Query: 339 KECVDLLLKHGAAVTLQ-NMDGKTPIDVAKLNNQDEVLKLL 220 + V L+ + A V ++ D TP+ +A + +V + L Sbjct: 547 NDFVMFLIGNNADVNVRTKSDLFTPLHLAARRDLTDVTQTL 587 Score = 40.0 bits (92), Expect = 0.006 Identities = 30/91 (32%), Positives = 44/91 (48%), Gaps = 2/91 (2%) Frame = -1 Query: 477 GRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLL-KHGAA 301 G LH A +++L GA ++ D N TPLHYAA G E VD LL + Sbjct: 635 GLTPLHLATLQNNLSVSKLLAGKGAYLNDGDANGMTPLHYAAMTGNLEMVDFLLNQQYIN 694 Query: 300 VTLQNMDGK-TPIDVAKLNNQDEVLKLLEKD 211 + + K TP+ +A L +++V + L D Sbjct: 695 INAATKEKKWTPLHLAILFKKNDVAERLLSD 725 Score = 35.0 bits (79), Expect = 0.20 Identities = 19/60 (31%), Positives = 31/60 (51%) Frame = -1 Query: 399 VDAMDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 ++A DK+ TPLH + + L+ A + +++ G TP+ +A L N V KLL Sbjct: 595 LNAQDKSGFTPLHLSISSTSETAAILIRNTNAVINIKSKVGLTPLHLATLQNNLSVSKLL 654 Score = 35.0 bits (79), Expect = 0.20 Identities = 26/112 (23%), Positives = 45/112 (40%) Frame = -1 Query: 501 DKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDL 322 D + +D G LH + A ++ A ++ K TPLH A L Sbjct: 594 DLNAQDKSGFTPLHLSISSTSETAAILIRNTNAVINIKSKVGLTPLHLATLQNNLSVSKL 653 Query: 321 LLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLLEKDVFL*IASLGSHEETW 166 L GA + + +G TP+ A + E++ L ++ I + + E+ W Sbjct: 654 LAGKGAYLNDGDANGMTPLHYAAMTGNLEMVDFLLNQQYINI-NAATKEKKW 704
>V014_FOWPV (Q9J5I7) Putative ankyrin repeat protein FPV014| Length = 437 Score = 55.5 bits (132), Expect = 1e-07 Identities = 34/115 (29%), Positives = 60/115 (52%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMD 385 ++ A+ G+ E K +D GA + +H A G ++ LL GA D D Sbjct: 136 INDAAANGNLEICKLLIDAGARINSRSMGSVYTIHHAIRSGNYELVVELLSRGALPDVED 195 Query: 384 KNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 + + LH+A G + V LL+HGA+V +Q+ G+TP+ +A ++ +++K+L Sbjct: 196 ELSFSSLHHAVMEGSADMVLTLLEHGASVDVQDFCGRTPLFLAANASELDIVKVL 250 Score = 49.7 bits (117), Expect = 8e-06 Identities = 36/107 (33%), Positives = 49/107 (45%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMD 385 +HH G+ E + + L GA D ED +LH A G LLE GA+VD D Sbjct: 169 IHHAIRSGNYELVVELLSRGALPDVEDELSFSSLHHAVMEGSADMVLTLLEHGASVDVQD 228 Query: 384 KNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNN 244 TPL AA + V +LL A ++ + TP+ V LN+ Sbjct: 229 FCGRTPLFLAANASELDIVKVLLDFWADTSVSS-GRNTPLSVCDLNS 274
>ANKR7_HUMAN (Q92527) Ankyrin repeat domain-containing protein 7| (Testis-specific protein TSA806) Length = 201 Score = 55.5 bits (132), Expect = 1e-07 Identities = 38/92 (41%), Positives = 49/92 (53%), Gaps = 1/92 (1%) Frame = -1 Query: 486 DSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLLKHG 307 DSE + L A CA ILL GA D D NT LHYA V+ LL++ Sbjct: 36 DSENKSPLIKAVQCQNEDCATILLNFGADPDLRDIRYNTVLHYAVCGQSLSLVEKLLEYE 95 Query: 306 AAVTLQNMDGKTPIDVAKLNNQDEVLK-LLEK 214 A + +N DG TP+ VA +NN +++K LLEK Sbjct: 96 ADLEAKNKDGYTPLLVAVINNNPKMVKFLLEK 127 Score = 39.7 bits (91), Expect = 0.008 Identities = 31/99 (31%), Positives = 45/99 (45%) Frame = -1 Query: 516 LDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRK 337 L+ GAD D D LH+A E LLE A ++A +K+ TPL A Sbjct: 59 LNFGADPDLRDIRYNTVLHYAVCGQSLSLVEKLLEYEADLEAKNKDGYTPLLVAVINNNP 118 Query: 336 ECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 + V LL+ GA V + +T + +A ++KLL Sbjct: 119 KMVKFLLEKGADVNASDNYQRTALILAVSGEPPCLVKLL 157 Score = 33.5 bits (75), Expect = 0.59 Identities = 31/96 (32%), Positives = 44/96 (45%), Gaps = 2/96 (2%) Frame = -1 Query: 564 VHHTASVGDGEGL-KKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAM 388 V H A G L +K L+ AD + ++ +G L A K + LLE GA V+A Sbjct: 75 VLHYAVCGQSLSLVEKLLEYEADLEAKNKDGYTPLLVAVINNNPKMVKFLLEKGADVNAS 134 Query: 387 DKNKNTPLHYAAGYGRKEC-VDLLLKHGAAVTLQNM 283 D + T L A G C V LLL+ G + + + Sbjct: 135 DNYQRTALILAVS-GEPPCLVKLLLQQGVELCYEGI 169
>AKT6_ARATH (Q8GXE6) Potassium channel AKT6 (Shaker pollen inward rectifier| K(+) channel) (Potassium channel SPIK) Length = 888 Score = 55.5 bits (132), Expect = 1e-07 Identities = 31/86 (36%), Positives = 47/86 (54%) Frame = -1 Query: 468 ALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQ 289 +L FA G+ LL G++ + MDK+ T LH AA G CV LLL+HGA ++ Sbjct: 547 SLCFAAARGDDLLLHQLLRRGSSPNEMDKDGRTALHIAASKGSHYCVVLLLEHGADPNIR 606 Query: 288 NMDGKTPIDVAKLNNQDEVLKLLEKD 211 + +G P+ A + E+ KLL ++ Sbjct: 607 DSEGNVPLWEAIIGRHREIAKLLAEN 632 Score = 53.1 bits (126), Expect = 7e-07 Identities = 34/100 (34%), Positives = 50/100 (50%) Frame = -1 Query: 552 ASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKN 373 A+ GD L + L G+ +E D +GR ALH A G C +LLE GA + D N Sbjct: 552 AARGDDLLLHQLLRRGSSPNEMDKDGRTALHIAASKGSHYCVVLLLEHGADPNIRDSEGN 611 Query: 372 TPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAK 253 PL A +E LL ++GA ++L ++ + + V K Sbjct: 612 VPLWEAIIGRHREIAKLLAENGAKLSLDSVSYFSGLAVEK 651 Score = 38.9 bits (89), Expect = 0.014 Identities = 37/119 (31%), Positives = 57/119 (47%), Gaps = 4/119 (3%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMD 385 +H AS G + L+ GAD + DSEG L A + A++L E GA + ++D Sbjct: 581 LHIAASKGSHYCVVLLLEHGADPNIRDSEGNVPLWEAIIGRHREIAKLLAENGAKL-SLD 639 Query: 384 KNKNTPLHYAAGYG-RKECVDLL---LKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 + Y +G K C+D L +K+G VTL + +G T + A E++K L Sbjct: 640 S-----VSYFSGLAVEKNCLDALKDIIKYGGDVTLPDGNGTTALHRAVSEGHLEIVKFL 693 Score = 36.6 bits (83), Expect = 0.070 Identities = 24/75 (32%), Positives = 31/75 (41%) Frame = -1 Query: 534 EGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYA 355 + LK + G D D G ALH A G + + LL+ GA +D D TP A Sbjct: 655 DALKDIIKYGGDVTLPDGNGTTALHRAVSEGHLEIVKFLLDQGADLDWPDSYGWTPRGLA 714 Query: 354 AGYGRKECVDLLLKH 310 G +E L H Sbjct: 715 DHQGNEEIKTLFHNH 729
>ZDH13_PONPY (Q5NVB9) Probable palmitoyltransferase ZDHHC13 (EC 2.3.1.-) (Zinc| finger DHHC domain-containing protein 13) (DHHC-13) Length = 622 Score = 55.5 bits (132), Expect = 1e-07 Identities = 34/126 (26%), Positives = 66/126 (52%), Gaps = 1/126 (0%) Frame = -1 Query: 420 LLEAGAAVDAMDK-NKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNN 244 LL+ +++ +DK ++NTPLH+A G VD LL+ G+++ +QN+ G+TP+D+A N Sbjct: 202 LLKFNPSLNVVDKIHQNTPLHWAVAAGNVNAVDKLLEAGSSLDIQNVKGETPLDMALQNK 261 Query: 243 QDEVLKLLEKDVFL*IASLGSHEETWPSSCFTSLWHWLDSHTRIGILFVV*EYTTCVSWP 64 ++ +L+ + A + ++++ LW WL LF++ + W Sbjct: 262 NQLIIHMLKTE-----AKMRANQK-------FRLWRWLQKCE----LFLLLMLSVITMWA 305 Query: 63 AGRLAE 46 G + + Sbjct: 306 VGYILD 311 Score = 50.4 bits (119), Expect = 5e-06 Identities = 33/96 (34%), Positives = 48/96 (50%), Gaps = 1/96 (1%) Frame = -1 Query: 534 EGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKN-TPLHY 358 E K+ ++ G D + D E LH+A + + GA VD + + N TPLH+ Sbjct: 63 ERCKELVEAGYDVRQPDKENVSLLHWAAINNRLDLVKFYISKGAVVDQLGGDLNSTPLHW 122 Query: 357 AAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKL 250 A G V LLL+HGA TL + +G + I +A L Sbjct: 123 AIRQGHLPMVILLLQHGADPTLIDGEGFSSIHLAVL 158 Score = 32.0 bits (71), Expect = 1.7 Identities = 20/53 (37%), Positives = 27/53 (50%) Frame = -1 Query: 456 ACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLLKHGAAV 298 A YG F+ + L+EAG V DK + LH+AA R + V + GA V Sbjct: 56 ATQYGIFERCKELVEAGYDVRQPDKENVSLLHWAAINNRLDLVKFYISKGAVV 108
>ZDH13_MACFA (Q4R690) Probable palmitoyltransferase ZDHHC13 (EC 2.3.1.-) (Zinc| finger DHHC domain-containing protein 13) (DHHC-13) Length = 622 Score = 55.5 bits (132), Expect = 1e-07 Identities = 34/126 (26%), Positives = 66/126 (52%), Gaps = 1/126 (0%) Frame = -1 Query: 420 LLEAGAAVDAMDK-NKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNN 244 LL+ +++ +DK ++NTPLH+A G VD LL+ G+++ +QN+ G+TP+D+A N Sbjct: 202 LLKFNPSLNVVDKIHQNTPLHWAVAAGNVNAVDKLLEAGSSLDIQNVKGETPLDMALQNK 261 Query: 243 QDEVLKLLEKDVFL*IASLGSHEETWPSSCFTSLWHWLDSHTRIGILFVV*EYTTCVSWP 64 ++ +L+ + A + ++++ LW WL LF++ + W Sbjct: 262 NQLIIHMLKTE-----AKMRTNQK-------FRLWRWLQKCE----LFLLLMLSVITMWA 305 Query: 63 AGRLAE 46 G + + Sbjct: 306 VGYILD 311 Score = 51.2 bits (121), Expect = 3e-06 Identities = 33/96 (34%), Positives = 48/96 (50%), Gaps = 1/96 (1%) Frame = -1 Query: 534 EGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKN-TPLHY 358 E K+ ++ G D + D E LH+A + + GA VD + + N TPLH+ Sbjct: 63 ERCKELVEAGYDVRQPDKENVSLLHWAAINNRLDLVKFYISKGAVVDQLGGDLNSTPLHW 122 Query: 357 AAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKL 250 A G V LLL+HGA TL + +G + I +A L Sbjct: 123 AIRQGHLPMVILLLQHGADPTLTDGEGFSSIHLAVL 158 Score = 32.0 bits (71), Expect = 1.7 Identities = 20/53 (37%), Positives = 27/53 (50%) Frame = -1 Query: 456 ACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLLKHGAAV 298 A YG F+ + L+EAG V DK + LH+AA R + V + GA V Sbjct: 56 ATQYGIFERCKELVEAGYDVRQPDKENVSLLHWAAINNRLDLVKFYISKGAVV 108
>YMV8_YEAST (Q04749) Hypothetical 47.1 kDa protein in NCA1-HMS1 intergenic| region Length = 426 Score = 55.5 bits (132), Expect = 1e-07 Identities = 34/95 (35%), Positives = 48/95 (50%), Gaps = 7/95 (7%) Frame = -1 Query: 477 GRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLLKHGAAV 298 GR +H AC ++C +L+ GA + MD N +TPLH YG C+ +LL G Sbjct: 109 GRAPIHIACMNDYYQCLSLLIGVGADLWVMDTNGDTPLHVCLEYGSISCMKMLLNEGEVS 168 Query: 297 TLQNMDGK---TPIDVAKL----NNQDEVLKLLEK 214 N+ K PIDVA+ N +VLK ++K Sbjct: 169 LDDNVRDKGNWKPIDVAQTFEVGNIYSKVLKEVKK 203 Score = 34.7 bits (78), Expect = 0.26 Identities = 25/99 (25%), Positives = 45/99 (45%), Gaps = 3/99 (3%) Frame = -1 Query: 507 GADKDE--EDSEGRRALHFACGYGEFKCAEILLEAGAA-VDAMDKNKNTPLHYAAGYGRK 337 G DK E + +G +H A G + +LL+ ++ +N P+H A Sbjct: 63 GHDKHELIKTFKGNTCVHLALMKGHEQTLHLLLQQFPRFINHRGENGRAPIHIACMNDYY 122 Query: 336 ECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 +C+ LL+ GA + + + +G TP+ V +K+L Sbjct: 123 QCLSLLIGVGADLWVMDTNGDTPLHVCLEYGSISCMKML 161
>FANK1_BOVIN (Q6B858) Fibronectin type 3 and ankyrin repeat domains protein 1| (GV14) Length = 345 Score = 55.5 bits (132), Expect = 1e-07 Identities = 36/119 (30%), Positives = 62/119 (52%), Gaps = 2/119 (1%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRA--LHFACGYGEFKCAEILLEAGAAVDA 391 +H A G ++ + G + D D+ R + + G + A +L++AGA V+ Sbjct: 214 LHWAADGGHCNVIEWMIGDGCEVDAVDAGSRWTPLMRVSAVSGNQEVASLLIDAGADVNV 273 Query: 390 MDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLLEK 214 DK+ TPL A +E V LLL GA +++N GK +++A++ ++ VL LLE+ Sbjct: 274 KDKDGKTPLMVAVLNNHEELVQLLLDRGADASVKNEFGKGVLEMARVFDRQNVLSLLEE 332 Score = 52.4 bits (124), Expect = 1e-06 Identities = 38/138 (27%), Positives = 58/138 (42%), Gaps = 35/138 (25%) Frame = -1 Query: 528 LKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAG 349 +K + G D + ++ G+ +L AC G + L GA+ D D T LH+AA Sbjct: 160 VKILISHGTDVNLQNGSGKDSLMLACYAGHLDVVKYLRRHGASWDTRDMGGCTALHWAAD 219 Query: 348 -----------------------------------YGRKECVDLLLKHGAAVTLQNMDGK 274 G +E LL+ GA V +++ DGK Sbjct: 220 GGHCNVIEWMIGDGCEVDAVDAGSRWTPLMRVSAVSGNQEVASLLIDAGADVNVKDKDGK 279 Query: 273 TPIDVAKLNNQDEVLKLL 220 TP+ VA LNN +E+++LL Sbjct: 280 TPLMVAVLNNHEELVQLL 297 Score = 35.0 bits (79), Expect = 0.20 Identities = 24/70 (34%), Positives = 32/70 (45%) Frame = -1 Query: 423 ILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNN 244 IL VD +K T L AA G V +L+ HG V LQN GK + +A Sbjct: 129 ILQGGNVKVDVPNKFGFTALMVAAQRGYTRLVKILISHGTDVNLQNGSGKDSLMLACYAG 188 Query: 243 QDEVLKLLEK 214 +V+K L + Sbjct: 189 HLDVVKYLRR 198
>ASB11_HUMAN (Q8WXH4) Ankyrin repeat and SOCS box protein 11 (ASB-11)| Length = 323 Score = 55.5 bits (132), Expect = 1e-07 Identities = 38/119 (31%), Positives = 57/119 (47%) Frame = -1 Query: 570 SIVHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDA 391 S +H G E ++ L + D E + L+ AC Y C + LLE GA+VD Sbjct: 165 SPIHEAVKRGHRECMEILLANNVNIDHEVPQLGTPLYVACTYQRVDCVKKLLELGASVDH 224 Query: 390 MDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLLEK 214 + +TPLH AA E + LL +GA + +N GK+ +D+A + E LL + Sbjct: 225 -GQWLDTPLHAAARQSNVEVIHLLTDYGANLKRRNAQGKSALDLAAPKSSVEQALLLRE 282 Score = 48.5 bits (114), Expect = 2e-05 Identities = 37/117 (31%), Positives = 56/117 (47%) Frame = -1 Query: 570 SIVHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDA 391 S +H A+ G LK + G + + +LH AC G CA+ LLE GA V+ Sbjct: 67 SPLHEAAAQGRLLALKTLIAQGVNVNLVTINRVSSLHEACLGGHVACAKALLENGAHVNG 126 Query: 390 MDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 + + TPL A G CV++LL+ GA L+ + +PI A E +++L Sbjct: 127 VTVHGATPLFNACCSGSAACVNVLLEFGAKAQLE-VHLASPIHEAVKRGHRECMEIL 182
>MIB2_MOUSE (Q8R516) Ubiquitin ligase protein MIB2 (EC 6.3.2.-) (Mind bomb| homolog 2) (Mind bomb-2) (Skeletrophin) (Dystrophin-like protein) (Dyslike) Length = 973 Score = 55.1 bits (131), Expect = 2e-07 Identities = 33/99 (33%), Positives = 47/99 (47%) Frame = -1 Query: 552 ASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKN 373 A +G E ++ L A D D EG LH+ + + +LL AG AVDA + ++ Sbjct: 489 AYLGQVELVRLLLQARASMDLPDDEGNTVLHYTAMGNQPEATRVLLSAGCAVDARNGTRS 548 Query: 372 TPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVA 256 T LH A G E V +L + G V L + TP+ A Sbjct: 549 TALHVAVQRGFLEVVKILCERGCDVNLPDAHADTPLHSA 587 Score = 52.8 bits (125), Expect = 9e-07 Identities = 32/88 (36%), Positives = 46/88 (52%) Frame = -1 Query: 483 SEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLLKHGA 304 ++GR AL A G+ + +LL+A A++D D NT LHY A + E +LL G Sbjct: 479 NQGRTALQVAAYLGQVELVRLLLQARASMDLPDDEGNTVLHYTAMGNQPEATRVLLSAGC 538 Query: 303 AVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 AV +N T + VA EV+K+L Sbjct: 539 AVDARNGTRSTALHVAVQRGFLEVVKIL 566 Score = 49.7 bits (117), Expect = 8e-06 Identities = 36/110 (32%), Positives = 51/110 (46%), Gaps = 3/110 (2%) Frame = -1 Query: 570 SIVHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDA 391 +++H+TA E + L G D + ALH A G + +IL E G V+ Sbjct: 516 TVLHYTAMGNQPEATRVLLSAGCAVDARNGTRSTALHVAVQRGFLEVVKILCERGCDVNL 575 Query: 390 MDKNKNTPLHYA--AGYGRKECVDLLLK-HGAAVTLQNMDGKTPIDVAKL 250 D + +TPLH A AG G V++L + G VT N G T + A L Sbjct: 576 PDAHADTPLHSAISAGAGASSIVEVLTEVPGIDVTATNSQGFTLLHHASL 625
>EHMT2_HUMAN (Q96KQ7) Histone-lysine N-methyltransferase, H3 lysine-9 specific 3| (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a) Length = 1210 Score = 55.1 bits (131), Expect = 2e-07 Identities = 34/92 (36%), Positives = 48/92 (52%) Frame = -1 Query: 534 EGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYA 355 E ++ L GAD D+E LH+A G AE+LL A + A++ + +TPLH A Sbjct: 799 EVIRMLLTRGADVTLTDNEENICLHWASFTGSAAIAEVLLNARCDLHAVNYHGDTPLHIA 858 Query: 354 AGYGRKECVDLLLKHGAAVTLQNMDGKTPIDV 259 A +CV L L GA L+N +G T D+ Sbjct: 859 ARESYHDCVLLFLSRGANPELRNKEGDTAWDL 890 Score = 48.5 bits (114), Expect = 2e-05 Identities = 36/116 (31%), Positives = 55/116 (47%), Gaps = 1/116 (0%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMD 385 +H A G E L GA+ + D + R L A + A +++ G V + + Sbjct: 689 LHAAAQKGSVEICHVLLQAGANINAVDKQQRTPLMEAVVNNHLEVARYMVQRGGCVYSKE 748 Query: 384 KNKNTPLHYAAGYGRKECVDLLLKHGAA-VTLQNMDGKTPIDVAKLNNQDEVLKLL 220 ++ +T LH+AA G E V LLL G V Q+ G TPI A + EV+++L Sbjct: 749 EDGSTCLHHAAKIGNLEMVSLLLSTGQVDVNAQDSGGWTPIIWAAEHKHIEVIRML 804 Score = 47.8 bits (112), Expect = 3e-05 Identities = 32/100 (32%), Positives = 48/100 (48%), Gaps = 1/100 (1%) Frame = -1 Query: 516 LDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRK 337 LD D++ R LH A G + +LL+AGA ++A+DK + TPL A Sbjct: 674 LDPNFQSDQQSK--RTPLHAAAQKGSVEICHVLLQAGANINAVDKQQRTPLMEAVVNNHL 731 Query: 336 ECVDLLLKHGAAVTLQNMDGKTPI-DVAKLNNQDEVLKLL 220 E +++ G V + DG T + AK+ N + V LL Sbjct: 732 EVARYMVQRGGCVYSKEEDGSTCLHHAAKIGNLEMVSLLL 771 Score = 47.0 bits (110), Expect = 5e-05 Identities = 30/104 (28%), Positives = 49/104 (47%), Gaps = 1/104 (0%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGG-ADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAM 388 +HH A +G+ E + L G D + +DS G + +A + + +LL GA V Sbjct: 755 LHHAAKIGNLEMVSLLLSTGQVDVNAQDSGGWTPIIWAAEHKHIEVIRMLLTRGADVTLT 814 Query: 387 DKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVA 256 D +N LH+A+ G ++LL + N G TP+ +A Sbjct: 815 DNEENICLHWASFTGSAAIAEVLLNARCDLHAVNYHGDTPLHIA 858 Score = 39.7 bits (91), Expect = 0.008 Identities = 25/91 (27%), Positives = 42/91 (46%), Gaps = 1/91 (1%) Frame = -1 Query: 489 EDSEGRRALHFACGYGEFKCAEILLEAGAA-VDAMDKNKNTPLHYAAGYGRKECVDLLLK 313 ++ +G LH A G + +LL G V+A D TP+ +AA + E + +LL Sbjct: 747 KEEDGSTCLHHAAKIGNLEMVSLLLSTGQVDVNAQDSGGWTPIIWAAEHKHIEVIRMLLT 806 Query: 312 HGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 GA VTL + + + A + ++L Sbjct: 807 RGADVTLTDNEENICLHWASFTGSAAIAEVL 837
>YL093_MIMIV (Q5UPG5) Putative ankyrin repeat protein L93| Length = 421 Score = 55.1 bits (131), Expect = 2e-07 Identities = 40/113 (35%), Positives = 57/113 (50%), Gaps = 5/113 (4%) Frame = -1 Query: 534 EGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYA 355 E +K LD GAD + + EG AL FAC Y + ++LL+ A ++A DK T L A Sbjct: 269 EIIKLLLDKGADINTGNGEGWTALMFACKYANIEAIKLLLDKNADINAKDKIGLTALMLA 328 Query: 354 AGYGRK----ECVDLLLKHGAAVTLQNMDGKTPIDVA-KLNNQDEVLKLLEKD 211 Y E + LLL GA + N +G T + A K N + + LL+K+ Sbjct: 329 CKYANTPNSIEIIKLLLDKGADINTGNGEGWTALMFACKYANIEAIKLLLDKN 381 Score = 54.7 bits (130), Expect = 2e-07 Identities = 31/79 (39%), Positives = 44/79 (55%) Frame = -1 Query: 534 EGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYA 355 E +K LD GAD + + EG AL FAC Y + ++LL+ A ++A DK+ TPL +A Sbjct: 339 EIIKLLLDKGADINTGNGEGWTALMFACKYANIEAIKLLLDKNADINAKDKDGWTPLMFA 398 Query: 354 AGYGRKECVDLLLKHGAAV 298 Y E + LLL A + Sbjct: 399 CVYANIETIKLLLDKRADI 417 Score = 52.4 bits (124), Expect = 1e-06 Identities = 35/109 (32%), Positives = 53/109 (48%), Gaps = 4/109 (3%) Frame = -1 Query: 534 EGLKKALDGGADKDEEDSEGRRALHFACGYGE----FKCAEILLEAGAAVDAMDKNKNTP 367 E +K LD AD + +D G AL AC Y + ++LL+ GA ++ + T Sbjct: 302 EAIKLLLDKNADINAKDKIGLTALMLACKYANTPNSIEIIKLLLDKGADINTGNGEGWTA 361 Query: 366 LHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 L +A Y E + LLL A + ++ DG TP+ A + E +KLL Sbjct: 362 LMFACKYANIEAIKLLLDKNADINAKDKDGWTPLMFACVYANIETIKLL 410 Score = 46.2 bits (108), Expect = 9e-05 Identities = 34/111 (30%), Positives = 52/111 (46%), Gaps = 8/111 (7%) Frame = -1 Query: 528 LKKALDGGADKDEEDSEGRRALHFACGY----GEFKCAEILLEAGAAVDAMDKNKNTPLH 361 +K LD GAD + +D G AL AC Y + ++LL+ GA ++ + T L Sbjct: 234 IKLLLDRGADTNIKDKIGLTALMLACKYANTPNSIEIIKLLLDKGADINTGNGEGWTALM 293 Query: 360 YAAGYGRKECVDLLLKHGAAVTLQNMDGKTPI----DVAKLNNQDEVLKLL 220 +A Y E + LLL A + ++ G T + A N E++KLL Sbjct: 294 FACKYANIEAIKLLLDKNADINAKDKIGLTALMLACKYANTPNSIEIIKLL 344
>ZDH13_HUMAN (Q8IUH4) Probable palmitoyltransferase ZDHHC13 (EC 2.3.1.-) (Zinc| finger DHHC domain-containing protein 13) (DHHC-13) (Huntingtin-interacting protein 14-related protein) (HIP14-related protein) (Huntingtin-interacting protein HIP3RP) (Putativ Length = 622 Score = 55.1 bits (131), Expect = 2e-07 Identities = 34/126 (26%), Positives = 66/126 (52%), Gaps = 1/126 (0%) Frame = -1 Query: 420 LLEAGAAVDAMDK-NKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNN 244 LL+ +++ +DK ++NTPLH+A G VD LL+ G+++ +QN+ G+TP+D+A N Sbjct: 202 LLKFNPSLNVVDKIHQNTPLHWAVAAGNVNAVDKLLEAGSSLDIQNVKGETPLDMALQNK 261 Query: 243 QDEVLKLLEKDVFL*IASLGSHEETWPSSCFTSLWHWLDSHTRIGILFVV*EYTTCVSWP 64 ++ +L+ + A + ++++ LW WL LF++ + W Sbjct: 262 NQLIIHMLKTE-----AKMRANQK-------FRLWRWLQKCE----LFLLLMLSVITMWA 305 Query: 63 AGRLAE 46 G + + Sbjct: 306 IGYILD 311 Score = 50.1 bits (118), Expect = 6e-06 Identities = 33/96 (34%), Positives = 47/96 (48%), Gaps = 1/96 (1%) Frame = -1 Query: 534 EGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKN-TPLHY 358 E K+ ++ G D + D E LH+A + GA VD + + N TPLH+ Sbjct: 63 ERCKELVEAGYDVRQPDKENVSLLHWAAINNRLDLVRFYISKGAVVDQLGGDLNSTPLHW 122 Query: 357 AAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKL 250 A G V LLL+HGA TL + +G + I +A L Sbjct: 123 AIRQGHLPMVILLLQHGADPTLIDGEGFSSIHLAVL 158 Score = 31.6 bits (70), Expect = 2.2 Identities = 20/53 (37%), Positives = 27/53 (50%) Frame = -1 Query: 456 ACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLLKHGAAV 298 A YG F+ + L+EAG V DK + LH+AA R + V + GA V Sbjct: 56 ATQYGIFERCKELVEAGYDVRQPDKENVSLLHWAAINNRLDLVRFYISKGAVV 108
>ASB11_PONPY (Q5RFS1) Ankyrin repeat and SOCS box protein 11 (ASB-11)| Length = 323 Score = 55.1 bits (131), Expect = 2e-07 Identities = 38/117 (32%), Positives = 56/117 (47%) Frame = -1 Query: 570 SIVHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDA 391 S +H G E ++ L + D E + L+ AC Y C + LLE GA+VD Sbjct: 165 SPIHEAVKRGHRECMEILLANNVNIDHEVPQLGTPLYVACTYQRVDCVKKLLELGASVDH 224 Query: 390 MDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 + +TPLH AA E + LL +GA + +N GK+ +D+A + E LL Sbjct: 225 -GQWLDTPLHAAARQSNVEVIHLLTDYGANLKRRNAQGKSALDLAAPKSSVEQALLL 280 Score = 47.0 bits (110), Expect = 5e-05 Identities = 36/117 (30%), Positives = 55/117 (47%) Frame = -1 Query: 570 SIVHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDA 391 S +H A+ G LK + G + + +LH AC G CA+ LLE GA V+ Sbjct: 67 SPLHEAAAQGRLLALKTLIAQGVNVNLVTINRVSSLHEACLGGHVACAKALLENGAHVNG 126 Query: 390 MDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 + + TPL A G CV++LL+ GA + + +PI A E +++L Sbjct: 127 VTVHGATPLFNACCSGSAACVNVLLEFGAKAQFE-VHLASPIHEAVKRGHRECMEIL 182
>CMTA3_ARATH (Q8GSA7) Calmodulin-binding transcription activator 3| (Signal-responsive protein 1) (Ethylene-induced calmodulin-binding protein a) (EICBP.a) (Ethylene-induced calmodulin-binding protein 1) (EICBP1) Length = 1032 Score = 54.7 bits (130), Expect = 2e-07 Identities = 39/111 (35%), Positives = 53/111 (47%), Gaps = 6/111 (5%) Frame = -1 Query: 528 LKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAG 349 L+K +GG D G+ LHFA G E + AG +VD D N T LH+AA Sbjct: 645 LQKIAEGGKGPSVLDEGGQGVLHFAASLGYNWALEPTIIAGVSVDFRDVNGWTALHWAAF 704 Query: 348 YGRKECVDLLLKHGAA---VTLQNMD---GKTPIDVAKLNNQDEVLKLLEK 214 +GR+ + L+ GAA +T N D G TP D+A N + L + Sbjct: 705 FGRERIIGSLIALGAAPGTLTDPNPDFPSGSTPSDLAYANGHKGIAGYLSE 755 Score = 35.0 bits (79), Expect = 0.20 Identities = 30/106 (28%), Positives = 47/106 (44%), Gaps = 8/106 (7%) Frame = -1 Query: 567 IVHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAM 388 ++H AS+G L+ + G D D G ALH+A +G + L+ GAA + Sbjct: 665 VLHFAASLGYNWALEPTIIAGVSVDFRDVNGWTALHWAAFFGRERIIGSLIALGAAPGTL 724 Query: 387 -DKNK-----NTPLHYAAGYGRKECVDLLLKHG--AAVTLQNMDGK 274 D N +TP A G K L ++ A V+L +++ K Sbjct: 725 TDPNPDFPSGSTPSDLAYANGHKGIAGYLSEYALRAHVSLLSLNDK 770
>AKR1_DEBHA (Q6BP80) Palmitoyltransferase AKR1 (EC 2.3.1.-) (Ankyrin| repeat-containing protein AKR1) Length = 821 Score = 54.7 bits (130), Expect = 2e-07 Identities = 34/95 (35%), Positives = 52/95 (54%), Gaps = 1/95 (1%) Frame = -1 Query: 495 DEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLL 316 DE D+ R +LH+A G+ LL+ GA V +DKN PLH+A G K + +L Sbjct: 284 DESDNCDRTSLHWAAYQGDLLTINALLKFGADVSKIDKNLFIPLHWAFMKGYKTVLKVLA 343 Query: 315 KHGAAVTLQNMDGKTPIDVAK-LNNQDEVLKLLEK 214 G+ + +N GK +VAK +N D +K+L++ Sbjct: 344 GAGSNIFAKNDQGKDSFEVAKDMNCYDTWIKVLKE 378 Score = 34.3 bits (77), Expect = 0.35 Identities = 30/104 (28%), Positives = 40/104 (38%), Gaps = 9/104 (8%) Frame = -1 Query: 504 ADKDEEDSEGRRALHFACGYGEFK---------CAEILLEAGAAVDAMDKNKNTPLHYAA 352 AD DS+ ALH A C VD D T LH+AA Sbjct: 239 ADPTLRDSQSYNALHLAVHSSNITLIIYLLLSCCGSTSTSKQLYVDESDNCDRTSLHWAA 298 Query: 351 GYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 G ++ LLK GA V+ + + P+ A + VLK+L Sbjct: 299 YQGDLLTINALLKFGADVSKIDKNLFIPLHWAFMKGYKTVLKVL 342
>V232_FOWPV (Q9J503) Putative ankyrin repeat protein FPV232| Length = 482 Score = 54.7 bits (130), Expect = 2e-07 Identities = 38/112 (33%), Positives = 62/112 (55%), Gaps = 5/112 (4%) Frame = -1 Query: 540 DGEGLKKALDGGAD-KDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPL 364 D + +K L GAD K + + + + ALH+A +K AE LL GA V++ D N+P+ Sbjct: 145 DTKIIKLLLAYGADTKIKTEDKLKTALHYASTNKNYKLAEYLLIYGAEVNSPDIGNNSPM 204 Query: 363 HYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVA---KLN-NQDEVLKLL 220 H A + ++ V +LL++G+ N G TP+ ++ LN N +LK+L Sbjct: 205 HEAVRHRNEDVVKILLQYGSNTDHMNSCGTTPLHISVGRVLNRNNYSILKIL 256 Score = 35.4 bits (80), Expect = 0.15 Identities = 30/110 (27%), Positives = 52/110 (47%), Gaps = 5/110 (4%) Frame = -1 Query: 570 SIVHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGY----GEFKCAEILLEAGA 403 S +H + + +K L G++ D +S G LH + G + +ILLE G Sbjct: 202 SPMHEAVRHRNEDVVKILLQYGSNTDHMNSCGTTPLHISVGRVLNRNNYSILKILLEHGT 261 Query: 402 AVDAMDKNKN-TPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVA 256 +V+ T LH + K ++LLL++GA + N + +TP+ +A Sbjct: 262 SVNIQSSILGFTALHLSIHSEDK--LNLLLEYGADPNILNFEKETPLSMA 309
>ANR10_MOUSE (Q99LW0) Ankyrin repeat domain-containing protein 10| Length = 415 Score = 54.7 bits (130), Expect = 2e-07 Identities = 36/116 (31%), Positives = 53/116 (45%), Gaps = 1/116 (0%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSE-GRRALHFACGYGEFKCAEILLEAGAAVDAM 388 VH A G E L + + GA + + + H A G +C L++AGA ++ Sbjct: 61 VHWAAHFGKLECLMQLVRAGASLNVSTTRYAQTPAHIAAFGGHPQCLVWLIQAGANINKP 120 Query: 387 DKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 D TP+H AA G EC+ L+ GA L+N G T D+A+ E + L Sbjct: 121 DCEGETPIHKAARSGSLECITALVGSGAHTDLRNASGLTAADIAQTQGFQECTQFL 176 Score = 33.5 bits (75), Expect = 0.59 Identities = 30/105 (28%), Positives = 50/105 (47%), Gaps = 4/105 (3%) Frame = -1 Query: 531 GLKKALDGGADKDEEDSEGRRALHFACGYGEFK--CAEILLEAGAAVDAMDKNKN-TPLH 361 G A++ G +E S R LH AC G+ C+ + A + A D TP+H Sbjct: 4 GAGVAVEAGFSSEELLSL-RFPLHRACRDGDLVALCSLLPHTPRAHLAAEDSFYGWTPVH 62 Query: 360 YAAGYGRKECVDLLLKHGAAVTLQNMD-GKTPIDVAKLNNQDEVL 229 +AA +G+ EC+ L++ GA++ + +TP +A + L Sbjct: 63 WAAHFGKLECLMQLVRAGASLNVSTTRYAQTPAHIAAFGGHPQCL 107
>ASB12_MOUSE (Q9D738) Ankyrin repeat and SOCS box protein 12 (ASB-12)| Length = 308 Score = 54.7 bits (130), Expect = 2e-07 Identities = 29/82 (35%), Positives = 43/82 (52%) Frame = -1 Query: 465 LHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQN 286 L A YG C ++LLE GA VD++D TPL A +G ECV +LL+ GA + Sbjct: 68 LRLAASYGHLNCVKVLLEHGADVDSLDVKAQTPLFTAVSHGHLECVRMLLEAGACPSGSI 127 Query: 285 MDGKTPIDVAKLNNQDEVLKLL 220 + +P+ A + +L+ L Sbjct: 128 YNNCSPVLTASRDGAFAILQEL 149 Score = 46.6 bits (109), Expect = 7e-05 Identities = 32/96 (33%), Positives = 45/96 (46%) Frame = -1 Query: 552 ASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKN 373 AS G +K L+ GAD D D + + L A +G +C +LLEAGA N Sbjct: 72 ASYGHLNCVKVLLEHGADVDSLDVKAQTPLFTAVSHGHLECVRMLLEAGACPSGSIYNNC 131 Query: 372 TPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPI 265 +P+ A+ G + LL HGA N+ K P+ Sbjct: 132 SPVLTASRDGAFAILQELLGHGAEA---NVKAKLPV 164 Score = 40.8 bits (94), Expect = 0.004 Identities = 20/51 (39%), Positives = 30/51 (58%) Frame = -1 Query: 372 TPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 TPL AA YG CV +LL+HGA V ++ +TP+ A + E +++L Sbjct: 66 TPLRLAASYGHLNCVKVLLEHGADVDSLDVKAQTPLFTAVSHGHLECVRML 116
>AKT5_ARATH (Q9SCX5) Probable potassium channel AKT5| Length = 880 Score = 54.7 bits (130), Expect = 2e-07 Identities = 31/86 (36%), Positives = 47/86 (54%) Frame = -1 Query: 468 ALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQ 289 +L FA G+ LL+ G+ + DKN T LH AA G + CV LLL+HGA ++ Sbjct: 545 SLCFAAARGDDLLLHQLLKRGSNPNETDKNGRTALHIAASKGSQYCVVLLLEHGADPNIR 604 Query: 288 NMDGKTPIDVAKLNNQDEVLKLLEKD 211 + +G P+ A + +E KLL ++ Sbjct: 605 DSEGSVPLWEAIIGRHEENAKLLSEN 630 Score = 47.4 bits (111), Expect = 4e-05 Identities = 30/90 (33%), Positives = 44/90 (48%) Frame = -1 Query: 552 ASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKN 373 A+ GD L + L G++ +E D GR ALH A G C +LLE GA + D + Sbjct: 550 AARGDDLLLHQLLKRGSNPNETDKNGRTALHIAASKGSQYCVVLLLEHGADPNIRDSEGS 609 Query: 372 TPLHYAAGYGRKECVDLLLKHGAAVTLQNM 283 PL A +E LL ++GA ++ + Sbjct: 610 VPLWEAIIGRHEENAKLLSENGATLSFDTV 639 Score = 35.0 bits (79), Expect = 0.20 Identities = 34/145 (23%), Positives = 54/145 (37%), Gaps = 31/145 (21%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRAL-------------------------- 463 +H AS G + L+ GAD + DSEG L Sbjct: 579 LHIAASKGSQYCVVLLLEHGADPNIRDSEGSVPLWEAIIGRHEENAKLLSENGATLSFDT 638 Query: 462 --HFAC---GYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLLKHGAAV 298 +F+C G + +++ G + D N T LH A G E V LL+ GA + Sbjct: 639 VGYFSCLAVGQNNLNALKDIVKYGGDISLSDVNGTTALHRAVSEGNLEIVQFLLEKGADM 698 Query: 297 TLQNMDGKTPIDVAKLNNQDEVLKL 223 ++ G T +A+ +++ L Sbjct: 699 DKPDVYGWTARALAEHQGHEDIKAL 723
>EHMT2_MOUSE (Q9Z148) Histone-lysine N-methyltransferase, H3 lysine-9 specific 3| (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a) Length = 1263 Score = 54.3 bits (129), Expect = 3e-07 Identities = 33/90 (36%), Positives = 47/90 (52%) Frame = -1 Query: 528 LKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAG 349 ++ L GAD D+E LH+A G AE+LL A + A++ + +TPLH AA Sbjct: 854 IRMLLTRGADVTLTDNEENICLHWASFTGSAAIAEVLLNAQCDLHAVNYHGDTPLHIAAR 913 Query: 348 YGRKECVDLLLKHGAAVTLQNMDGKTPIDV 259 +CV L L GA L+N +G T D+ Sbjct: 914 ESYHDCVLLFLSRGANPELRNKEGDTAWDL 943 Score = 47.4 bits (111), Expect = 4e-05 Identities = 35/116 (30%), Positives = 55/116 (47%), Gaps = 1/116 (0%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMD 385 +H A G E L GA+ + D + R L A + A +++ G V + + Sbjct: 742 LHAAAQKGSVEICHVLLQAGANINAVDKQQRTPLMEAVVNNHLEVARYMVQLGGCVYSKE 801 Query: 384 KNKNTPLHYAAGYGRKECVDLLLKHGAA-VTLQNMDGKTPIDVAKLNNQDEVLKLL 220 ++ +T LH+AA G E V LLL G V Q+ G TPI A + +V+++L Sbjct: 802 EDGSTCLHHAAKIGNLEMVSLLLSTGQVDVNAQDSGGWTPIIWAAEHKHIDVIRML 857 Score = 46.6 bits (109), Expect = 7e-05 Identities = 32/100 (32%), Positives = 48/100 (48%), Gaps = 1/100 (1%) Frame = -1 Query: 516 LDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRK 337 LD D++ R LH A G + +LL+AGA ++A+DK + TPL A Sbjct: 727 LDPNFQSDQQSK--RTPLHAAAQKGSVEICHVLLQAGANINAVDKQQRTPLMEAVVNNHL 784 Query: 336 ECVDLLLKHGAAVTLQNMDGKTPI-DVAKLNNQDEVLKLL 220 E +++ G V + DG T + AK+ N + V LL Sbjct: 785 EVARYMVQLGGCVYSKEEDGSTCLHHAAKIGNLEMVSLLL 824 Score = 46.2 bits (108), Expect = 9e-05 Identities = 30/104 (28%), Positives = 48/104 (46%), Gaps = 1/104 (0%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGG-ADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAM 388 +HH A +G+ E + L G D + +DS G + +A + +LL GA V Sbjct: 808 LHHAAKIGNLEMVSLLLSTGQVDVNAQDSGGWTPIIWAAEHKHIDVIRMLLTRGADVTLT 867 Query: 387 DKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVA 256 D +N LH+A+ G ++LL + N G TP+ +A Sbjct: 868 DNEENICLHWASFTGSAAIAEVLLNAQCDLHAVNYHGDTPLHIA 911 Score = 38.5 bits (88), Expect = 0.018 Identities = 24/91 (26%), Positives = 42/91 (46%), Gaps = 1/91 (1%) Frame = -1 Query: 489 EDSEGRRALHFACGYGEFKCAEILLEAGAA-VDAMDKNKNTPLHYAAGYGRKECVDLLLK 313 ++ +G LH A G + +LL G V+A D TP+ +AA + + + +LL Sbjct: 800 KEEDGSTCLHHAAKIGNLEMVSLLLSTGQVDVNAQDSGGWTPIIWAAEHKHIDVIRMLLT 859 Query: 312 HGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 GA VTL + + + A + ++L Sbjct: 860 RGADVTLTDNEENICLHWASFTGSAAIAEVL 890
>VB04_VACCV (P24769) Ankyrin repeat protein B4| Length = 558 Score = 54.3 bits (129), Expect = 3e-07 Identities = 39/126 (30%), Positives = 61/126 (48%), Gaps = 4/126 (3%) Frame = -1 Query: 567 IVHHTASVGDG--EGLKKALDGGADKDEEDSEGRRALHFACGY--GEFKCAEILLEAGAA 400 I H+ S + E +K L+ G+D D++D+ G C + + EI LE A Sbjct: 178 IYHYKKSESESYNELIKILLNNGSDVDKKDTYGNTPFILLCKHDINNVELFEICLE-NAN 236 Query: 399 VDAMDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 +D++D N+ TPLHY + + + V LL+ GA V +N G TP ++ + L Sbjct: 237 IDSVDFNRYTPLHYVSCRNKYDFVKLLISKGANVNARNRFGTTPFYCGIIHGISLIKLYL 296 Query: 219 EKDVFL 202 E D L Sbjct: 297 ESDTEL 302
>VB04_VACCC (P21001) Ankyrin repeat protein B4| Length = 558 Score = 54.3 bits (129), Expect = 3e-07 Identities = 39/126 (30%), Positives = 61/126 (48%), Gaps = 4/126 (3%) Frame = -1 Query: 567 IVHHTASVGDG--EGLKKALDGGADKDEEDSEGRRALHFACGY--GEFKCAEILLEAGAA 400 I H+ S + E +K L+ G+D D++D+ G C + + EI LE A Sbjct: 178 IYHYKKSESESYNELIKILLNNGSDVDKKDTYGNTPFILLCKHDINNVELFEICLE-NAN 236 Query: 399 VDAMDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 +D++D N+ TPLHY + + + V LL+ GA V +N G TP ++ + L Sbjct: 237 IDSVDFNRYTPLHYVSCRNKYDFVKLLISKGANVNARNKFGTTPFYCGIIHGISLIKLYL 296 Query: 219 EKDVFL 202 E D L Sbjct: 297 ESDTEL 302
>AKR_ARATH (Q05753) Ankyrin repeat protein, chloroplast precursor (AKRP)| Length = 435 Score = 54.3 bits (129), Expect = 3e-07 Identities = 38/122 (31%), Positives = 61/122 (50%), Gaps = 5/122 (4%) Frame = -1 Query: 564 VHHTASVGDGEGLKK-ALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAM 388 V H A +G + + L A+ D EG +H+A ++LL A ++A Sbjct: 296 VLHRAIIGKKQAITNYLLRESANPFVLDDEGATLMHYAVQTASAPTIKLLLLYNADINAQ 355 Query: 387 DKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQD----EVLKLL 220 D++ TPLH A R + V LLL GA + ++N DG TP+ + ++ EV+KLL Sbjct: 356 DRDGWTPLHVAVQARRSDIVKLLLIKGADIEVKNKDGLTPLGLCLYLGREIRTYEVMKLL 415 Query: 219 EK 214 ++ Sbjct: 416 KE 417 Score = 43.9 bits (102), Expect = 4e-04 Identities = 32/115 (27%), Positives = 49/115 (42%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMD 385 +H A+ G+ + L D + D G LH A + LL A +D Sbjct: 264 LHTLAACGEFYLVDSLLKHNLDINATDVGGLTVLHRAIIGKKQAITNYLLRESANPFVLD 323 Query: 384 KNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 T +HYA + LLL + A + Q+ DG TP+ VA + +++KLL Sbjct: 324 DEGATLMHYAVQTASAPTIKLLLLYNADINAQDRDGWTPLHVAVQARRSDIVKLL 378 Score = 33.1 bits (74), Expect = 0.77 Identities = 20/78 (25%), Positives = 35/78 (44%) Frame = -1 Query: 570 SIVHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDA 391 +++H+ +K L AD + +D +G LH A ++LL GA ++ Sbjct: 328 TLMHYAVQTASAPTIKLLLLYNADINAQDRDGWTPLHVAVQARRSDIVKLLLIKGADIEV 387 Query: 390 MDKNKNTPLHYAAGYGRK 337 +K+ TPL GR+ Sbjct: 388 KNKDGLTPLGLCLYLGRE 405
>ASZ1_CALJA (Q2QLG0) Ankyrin repeat, SAM and basic leucine zipper| domain-containing protein 1 (Germ cell-specific ankyrin, SAM and basic leucine zipper domain-containing protein) Length = 477 Score = 54.3 bits (129), Expect = 3e-07 Identities = 31/80 (38%), Positives = 43/80 (53%) Frame = -1 Query: 459 FACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMD 280 +A G + +L+ +GA V+ D+N T L +AA G K V LL+ GA LQ D Sbjct: 157 YAARDGHTQVVALLVASGAEVNTQDENGYTALTWAARQGHKSIVLKLLELGANKMLQTKD 216 Query: 279 GKTPIDVAKLNNQDEVLKLL 220 GK P ++AK N E+ LL Sbjct: 217 GKLPSEIAKRNKHHEIFNLL 236 Score = 30.0 bits (66), Expect = 6.5 Identities = 24/71 (33%), Positives = 39/71 (54%), Gaps = 3/71 (4%) Frame = -1 Query: 420 LLEAGA-AVDAMDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVA--KL 250 LL++G +VDA + TPL YAA E V +LL GA + + D +T + A Sbjct: 66 LLDSGIISVDATFRYGWTPLMYAASVANAELVRVLLDRGANASFEK-DKQTILITACSAH 124 Query: 249 NNQDEVLKLLE 217 +++++LK +E Sbjct: 125 GSEEQILKCVE 135
>ASZ1_PONPY (Q2IBE3) Ankyrin repeat, SAM and basic leucine zipper| domain-containing protein 1 (Germ cell-specific ankyrin, SAM and basic leucine zipper domain-containing protein) Length = 475 Score = 53.9 bits (128), Expect = 4e-07 Identities = 39/119 (32%), Positives = 59/119 (49%), Gaps = 5/119 (4%) Frame = -1 Query: 558 HTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGE----FKCAEILLEAGAAVDA 391 + ASV + E ++ LD GA+ E + + G KC E+LL A + Sbjct: 85 YAASVANAELVRVLLDRGANASFEKDKQSILITACSARGSEEQILKCVELLLSRNADPNV 144 Query: 390 MDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPID-VAKLNNQDEVLKLLE 217 + TP+ YAA G + V LL+ HGA V Q+ +G T + A+ +++ VLKLLE Sbjct: 145 ACRRLMTPIMYAARDGHTQVVALLVAHGAEVNTQDENGYTALTWAARQGHKNIVLKLLE 203 Score = 53.1 bits (126), Expect = 7e-07 Identities = 31/80 (38%), Positives = 42/80 (52%) Frame = -1 Query: 459 FACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMD 280 +A G + +L+ GA V+ D+N T L +AA G K V LL+ GA LQ D Sbjct: 155 YAARDGHTQVVALLVAHGAEVNTQDENGYTALTWAARQGHKNIVLKLLELGANKMLQTKD 214 Query: 279 GKTPIDVAKLNNQDEVLKLL 220 GK P ++AK N E+ LL Sbjct: 215 GKMPSEIAKRNKHHEIFNLL 234 Score = 34.7 bits (78), Expect = 0.26 Identities = 22/77 (28%), Positives = 38/77 (49%), Gaps = 1/77 (1%) Frame = -1 Query: 444 GEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPI 265 G+ + LL++G +VD+ + TPL YAA E V +LL GA + + I Sbjct: 57 GDVSLVQELLDSGISVDSTFQYGWTPLMYAASVANAELVRVLLDRGANASFEKDKQSILI 116 Query: 264 DVAKL-NNQDEVLKLLE 217 +++++LK +E Sbjct: 117 TACSARGSEEQILKCVE 133 Score = 32.7 bits (73), Expect = 1.0 Identities = 28/99 (28%), Positives = 42/99 (42%) Frame = -1 Query: 507 GADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECV 328 GA+ + +D G AL +A G LLE GA K+ P A E Sbjct: 172 GAEVNTQDENGYTALTWAARQGHKNIVLKLLELGANKMLQTKDGKMPSEIAKRNKHHEIF 231 Query: 327 DLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLLEKD 211 +LL + TL ++GK + +L +D + K+L D Sbjct: 232 NLL-----SFTLNPLEGK----LQQLTKEDTICKILTTD 261
>ASZ1_OTOGA (Q2QLH1) Ankyrin repeat, SAM and basic leucine zipper| domain-containing protein 1 (Germ cell-specific ankyrin, SAM and basic leucine zipper domain-containing protein) Length = 475 Score = 53.9 bits (128), Expect = 4e-07 Identities = 43/120 (35%), Positives = 63/120 (52%), Gaps = 6/120 (5%) Frame = -1 Query: 558 HTASVGDGEGLKKALDGGADKDEEDSEGRRALHFAC---GYGE--FKCAEILLEAGAAVD 394 + ASV + E ++ LD GA+ D + + L AC G E KC E+LL A + Sbjct: 85 YAASVANVELVRVLLDRGANASF-DKDKQTILITACSARGLEEQILKCVELLLSRNADPN 143 Query: 393 AMDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPID-VAKLNNQDEVLKLLE 217 + TP+ YAA G + V LL+ HGA V Q+ +G T + A+ +++ VLKLLE Sbjct: 144 VACRRLMTPIMYAARDGHPQVVALLVAHGAEVNTQDENGYTALTWAARQGHKNVVLKLLE 203 Score = 49.7 bits (117), Expect = 8e-06 Identities = 30/80 (37%), Positives = 41/80 (51%) Frame = -1 Query: 459 FACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMD 280 +A G + +L+ GA V+ D+N T L +AA G K V LL+ GA LQ D Sbjct: 155 YAARDGHPQVVALLVAHGAEVNTQDENGYTALTWAARQGHKNVVLKLLELGANKMLQTKD 214 Query: 279 GKTPIDVAKLNNQDEVLKLL 220 GK P ++AK N E+ L Sbjct: 215 GKIPSEIAKRNKHLEIFNFL 234 Score = 33.9 bits (76), Expect = 0.45 Identities = 30/112 (26%), Positives = 55/112 (49%), Gaps = 2/112 (1%) Frame = -1 Query: 546 VGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTP 367 +G + + L G +E++ ++AL G+ + LL++G +VD+ + TP Sbjct: 27 IGYLDRASQKLKGPLPIEEKNETFKKALTT----GDISLVQELLDSGISVDSSFRYGWTP 82 Query: 366 LHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVA--KLNNQDEVLKLLE 217 L YAA E V +LL GA + + D +T + A ++++LK +E Sbjct: 83 LMYAASVANVELVRVLLDRGANASF-DKDKQTILITACSARGLEEQILKCVE 133
>TRPA1_DROME (Q7Z020) Transient receptor potential cation channel subfamily A| member 1 (Ankyrin-like with transmembrane domains protein 1) (dANKTM1) Length = 1197 Score = 53.9 bits (128), Expect = 4e-07 Identities = 31/95 (32%), Positives = 48/95 (50%), Gaps = 3/95 (3%) Frame = -1 Query: 495 DEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLL 316 +E+DS G LH+A G + E L+ GA ++ + N +PLH+AA YGR V LL Sbjct: 438 NEKDSMGCSPLHYASRDGHIRSLENLIRLGACINLKNNNNESPLHFAARYGRYNTVRQLL 497 Query: 315 ---KHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 K + + G TP+ ++ V++LL Sbjct: 498 DSEKGSFIINESDGAGMTPLHISSQQGHTRVVQLL 532 Score = 48.5 bits (114), Expect = 2e-05 Identities = 32/120 (26%), Positives = 58/120 (48%), Gaps = 3/120 (2%) Frame = -1 Query: 570 SIVHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEA---GAA 400 S +H+ + G L+ + GA + +++ LHFA YG + LL++ Sbjct: 446 SPLHYASRDGHIRSLENLIRLGACINLKNNNNESPLHFAARYGRYNTVRQLLDSEKGSFI 505 Query: 399 VDAMDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 ++ D TPLH ++ G V LLL GA + ++ G+ P+ +A ++ E ++LL Sbjct: 506 INESDGAGMTPLHISSQQGHTRVVQLLLNRGALLH-RDHTGRNPLQLAAMSGYTETIELL 564 Score = 43.9 bits (102), Expect = 4e-04 Identities = 24/94 (25%), Positives = 46/94 (48%), Gaps = 5/94 (5%) Frame = -1 Query: 486 DSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLL---- 319 DSEG LH A G+ K E+ L++GA + + +TP+H A G + V L+ Sbjct: 263 DSEGNVPLHSAVHGGDIKAVELCLKSGAKISTQQHDLSTPVHLACAQGAIDIVKLMFEMQ 322 Query: 318 -LKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 ++ ++ ++ TP+ A + + +++ L Sbjct: 323 PMEKRLCLSCTDVQKMTPLHCASMFDHPDIVSYL 356 Score = 39.7 bits (91), Expect = 0.008 Identities = 34/136 (25%), Positives = 49/136 (36%), Gaps = 42/136 (30%) Frame = -1 Query: 501 DKDEEDSEGRRALHFACGYGEFKCAEILL------------------------------- 415 D + GR ALH A Y +CA IL+ Sbjct: 183 DIQQGGEHGRTALHLAAIYDHEECARILITEFDACPRKPCNNGYYPIHEAAKNASSKTME 242 Query: 414 -------EAGAAVDAM----DKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTP 268 + G + M D N PLH A G + V+L LK GA ++ Q D TP Sbjct: 243 VFFQWGEQRGCTREEMISFYDSEGNVPLHSAVHGGDIKAVELCLKSGAKISTQQHDLSTP 302 Query: 267 IDVAKLNNQDEVLKLL 220 + +A +++KL+ Sbjct: 303 VHLACAQGAIDIVKLM 318 Score = 35.8 bits (81), Expect = 0.12 Identities = 22/90 (24%), Positives = 39/90 (43%) Frame = -1 Query: 489 EDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLLKH 310 +D++GR A H A + + +A D NTPLH A + +D LL Sbjct: 86 KDAKGRTAAHQAAARNRVNILRYIRDQNGDFNAKDNAGNTPLHIAVESDAYDALDYLLSI 145 Query: 309 GAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 + N + P+ +A N+ + L+++ Sbjct: 146 PVDTGVLNEKKQAPVHLATELNKVKSLRVM 175 Score = 35.0 bits (79), Expect = 0.20 Identities = 22/116 (18%), Positives = 50/116 (43%), Gaps = 2/116 (1%) Frame = -1 Query: 561 HHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDK 382 H A+ L+ D D + +D+ G LH A + + LL +++ Sbjct: 95 HQAAARNRVNILRYIRDQNGDFNAKDNAGNTPLHIAVESDAYDALDYLLSIPVDTGVLNE 154 Query: 381 NKNTPLHYAAGYGRKECVDLLLKHGAAVTLQ--NMDGKTPIDVAKLNNQDEVLKLL 220 K P+H A + + + ++ ++ + +Q G+T + +A + + +E ++L Sbjct: 155 KKQAPVHLATELNKVKSLRVMGQYRNVIDIQQGGEHGRTALHLAAIYDHEECARIL 210 Score = 34.3 bits (77), Expect = 0.35 Identities = 20/80 (25%), Positives = 38/80 (47%) Frame = -1 Query: 486 DSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLLKHG 307 D + LH A + L+ GA ++A+DK +PL AA + V LL++ G Sbjct: 334 DVQKMTPLHCASMFDHPDIVSYLVAEGADINALDKEHRSPLLLAASRSGWKTVHLLIRLG 393 Query: 306 AAVTLQNMDGKTPIDVAKLN 247 A +++++ + + +N Sbjct: 394 ACISVKDAAARNVLHFVIMN 413
>NOTC2_MOUSE (O35516) Neurogenic locus notch homolog protein 2 precursor (Notch 2)| (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain] Length = 2470 Score = 53.9 bits (128), Expect = 4e-07 Identities = 31/97 (31%), Positives = 49/97 (50%) Frame = -1 Query: 504 ADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVD 325 AD + D G+ ALH+A + +LL+ GA D D + TPL AA G E Sbjct: 1966 ADVNAVDDHGKSALHWAAAVNNVEATLLLLKNGANRDMQDNKEETPLFLAAREGSYEAAK 2025 Query: 324 LLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLLEK 214 +LL H A + + + P DVA+ ++++LL++ Sbjct: 2026 ILLDHFANRDITDHMDRLPRDVARDRMHHDIVRLLDE 2062 Score = 46.2 bits (108), Expect = 9e-05 Identities = 39/149 (26%), Positives = 60/149 (40%), Gaps = 34/149 (22%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFAC---GYGEFK------------- 433 +H A + K+ LD GAD++ +D+ GR LH A G F+ Sbjct: 1879 LHLAARYSRADAAKRLLDAGADRNAQDNMGRCPLHAAVAGDAQGVFQILIRNRVTDLDAR 1938 Query: 432 ------------------CAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLLKHG 307 L+ A V+A+D + + LH+AA E LLLK+G Sbjct: 1939 MNDGTTPLILAARLAVEGMVAELINCQADVNAVDDHGKSALHWAAAVNNVEATLLLLKNG 1998 Query: 306 AAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 A +Q+ +TP+ +A E K+L Sbjct: 1999 ANRDMQDNKEETPLFLAAREGSYEAAKIL 2027 Score = 40.8 bits (94), Expect = 0.004 Identities = 26/86 (30%), Positives = 41/86 (47%), Gaps = 1/86 (1%) Frame = -1 Query: 510 GGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKEC 331 G + + + D G ALH A Y A+ LL+AGA +A D PLH A + Sbjct: 1864 GASLQAQTDRTGEMALHLAARYSRADAAKRLLDAGADRNAQDNMGRCPLHAAVAGDAQGV 1923 Query: 330 VDLLLKHGAA-VTLQNMDGKTPIDVA 256 +L+++ + + DG TP+ +A Sbjct: 1924 FQILIRNRVTDLDARMNDGTTPLILA 1949
>Y714_RICPR (Q9ZCL3) Hypothetical ANK-repeat protein RP714| Length = 107 Score = 53.9 bits (128), Expect = 4e-07 Identities = 32/80 (40%), Positives = 38/80 (47%) Frame = -1 Query: 543 GDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPL 364 G+ E + L G D D D G ALH A G K A +LL GA +DA + TPL Sbjct: 19 GNIEYTSELLQNGVDIDVRDKNGNSALHIAASKGYTKIATMLLLYGATIDAPNFELATPL 78 Query: 363 HYAAGYGRKECVDLLLKHGA 304 HYAA K+ LL A Sbjct: 79 HYAAANNYKDLTQYLLNMNA 98 Score = 48.9 bits (115), Expect = 1e-05 Identities = 25/75 (33%), Positives = 38/75 (50%) Frame = -1 Query: 444 GEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPI 265 G + LL+ G +D DKN N+ LH AA G + +LL +GA + N + TP+ Sbjct: 19 GNIEYTSELLQNGVDIDVRDKNGNSALHIAASKGYTKIATMLLLYGATIDAPNFELATPL 78 Query: 264 DVAKLNNQDEVLKLL 220 A NN ++ + L Sbjct: 79 HYAAANNYKDLTQYL 93
>ASZ1_CALMO (Q2QLB5) Ankyrin repeat, SAM and basic leucine zipper| domain-containing protein 1 (Germ cell-specific ankyrin, SAM and basic leucine zipper domain-containing protein) Length = 476 Score = 53.9 bits (128), Expect = 4e-07 Identities = 31/80 (38%), Positives = 42/80 (52%) Frame = -1 Query: 459 FACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMD 280 +A G + +L+ GA V+ D+N T L +AA G K V LL+ GA LQ D Sbjct: 156 YAARDGHTQVVALLVAGGAEVNTQDENGYTALTWAARQGHKSIVLKLLELGANKMLQTKD 215 Query: 279 GKTPIDVAKLNNQDEVLKLL 220 GK P ++AK N E+ LL Sbjct: 216 GKLPSEIAKRNKHHEIFNLL 235 Score = 36.6 bits (83), Expect = 0.070 Identities = 25/78 (32%), Positives = 42/78 (53%), Gaps = 2/78 (2%) Frame = -1 Query: 444 GEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPI 265 G+ + LL++G +VDA + TPL YAA E V +LL GA + + D +T + Sbjct: 58 GDVSLVQELLDSGISVDATFRYGWTPLMYAASVANAELVRVLLDRGANASFEK-DKQTIL 116 Query: 264 DVA--KLNNQDEVLKLLE 217 A +++++LK +E Sbjct: 117 ITACSAHGSEEQILKCVE 134 Score = 36.6 bits (83), Expect = 0.070 Identities = 33/115 (28%), Positives = 52/115 (45%), Gaps = 5/115 (4%) Frame = -1 Query: 549 SVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNT 370 + GD +++ LD G D G L +A + +LL+ GA + +K+K T Sbjct: 56 TTGDVSLVQELLDSGISVDATFRYGWTPLMYAASVANAELVRVLLDRGANA-SFEKDKQT 114 Query: 369 PLHYA-AGYGRKE----CVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 L A + +G +E CV+LLL A + TPI A + +V+ LL Sbjct: 115 ILITACSAHGSEEQILKCVELLLSRNADPNVACRRLMTPIMYAARDGHTQVVALL 169
>V246_FOWPV (Q9J4Z4) Putative ankyrin repeat protein FPV246| Length = 592 Score = 53.9 bits (128), Expect = 4e-07 Identities = 36/116 (31%), Positives = 62/116 (53%), Gaps = 1/116 (0%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMD 385 +H G E + + G+ D +D+ G L ACG + +++L+E GA + + Sbjct: 293 LHAATRSGSVETVNALISYGSTVDIKDNIGSTPLMHACGNKDI--SKLLIEKGADPNISN 350 Query: 384 KNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQN-MDGKTPIDVAKLNNQDEVLKLL 220 + TPLH AA YG + V+LLL +G ++ ++ + G TP+D + E++KLL Sbjct: 351 IHGYTPLHNAAAYGSVDVVNLLLSYGVSIDAKDKIIGSTPLDHGV--HHPEIVKLL 404 Score = 49.7 bits (117), Expect = 8e-06 Identities = 35/102 (34%), Positives = 51/102 (50%), Gaps = 1/102 (0%) Frame = -1 Query: 543 GDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKN-KNTP 367 G+ + K ++ GAD + + G LH A YG +LL G ++DA DK +TP Sbjct: 331 GNKDISKLLIEKGADPNISNIHGYTPLHNAAAYGSVDVVNLLLSYGVSIDAKDKIIGSTP 390 Query: 366 LHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQ 241 L + G E V LLL+ GA N+ G TP+ A L ++ Sbjct: 391 LDH--GVHHPEIVKLLLEKGANPNTINLYGYTPLKNAILKSR 430 Score = 41.2 bits (95), Expect = 0.003 Identities = 25/77 (32%), Positives = 39/77 (50%) Frame = -1 Query: 444 GEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPI 265 G LL+ G V++ D TPLH A G E V+ L+ +G+ V +++ G TP+ Sbjct: 267 GYINVIHFLLDIGFNVNSFDSFGETPLHAATRSGSVETVNALISYGSTVDIKDNIGSTPL 326 Query: 264 DVAKLNNQDEVLKLLEK 214 + N+D L+EK Sbjct: 327 -MHACGNKDISKLLIEK 342 Score = 34.3 bits (77), Expect = 0.35 Identities = 21/76 (27%), Positives = 40/76 (52%) Frame = -1 Query: 441 EFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPID 262 E K A++L+ GA +D ++ TPL G LLL +GA +++ +G T + Sbjct: 175 ELKIAQLLISRGAKLDIKNEYGYTPLRNTVINGNFALTKLLLDNGADASIK-CNGMTIFE 233 Query: 261 VAKLNNQDEVLKLLEK 214 ++ L+ +++K + K Sbjct: 234 ISTLSQNVDMIKEIIK 249
>NOTC2_RAT (Q9QW30) Neurogenic locus notch homolog protein 2 precursor (Notch 2)| [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain] Length = 2471 Score = 53.9 bits (128), Expect = 4e-07 Identities = 31/97 (31%), Positives = 49/97 (50%) Frame = -1 Query: 504 ADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVD 325 AD + D G+ ALH+A + +LL+ GA D D + TPL AA G E Sbjct: 1968 ADVNAVDDHGKSALHWAAAVNNVEATLLLLKNGANRDMQDNKEETPLFLAAREGSYEAAK 2027 Query: 324 LLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLLEK 214 +LL H A + + + P DVA+ ++++LL++ Sbjct: 2028 ILLDHFANRDITDHMDRLPRDVARDRMHHDIVRLLDE 2064 Score = 45.1 bits (105), Expect = 2e-04 Identities = 38/149 (25%), Positives = 58/149 (38%), Gaps = 34/149 (22%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLE--------- 412 +H A + K+ LD GAD + +D+ GR LH A +IL+ Sbjct: 1881 LHLAARYSRADAAKRLLDAGADANAQDNMGRCPLHAAVAADAQGVFQILIRNRVTDLDAR 1940 Query: 411 -------------------------AGAAVDAMDKNKNTPLHYAAGYGRKECVDLLLKHG 307 A V+A+D + + LH+AA E LLLK+G Sbjct: 1941 MNDGTTPLILAARLAVEGMVAELINCQADVNAVDDHGKSALHWAAAVNNVEATLLLLKNG 2000 Query: 306 AAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 A +Q+ +TP+ +A E K+L Sbjct: 2001 ANRDMQDNKEETPLFLAAREGSYEAAKIL 2029 Score = 42.4 bits (98), Expect = 0.001 Identities = 26/86 (30%), Positives = 41/86 (47%), Gaps = 1/86 (1%) Frame = -1 Query: 510 GGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKEC 331 G + + + D G ALH A Y A+ LL+AGA +A D PLH A + Sbjct: 1866 GASLQAQTDRTGEMALHLAARYSRADAAKRLLDAGADANAQDNMGRCPLHAAVAADAQGV 1925 Query: 330 VDLLLKHGAA-VTLQNMDGKTPIDVA 256 +L+++ + + DG TP+ +A Sbjct: 1926 FQILIRNRVTDLDARMNDGTTPLILA 1951
>NOTC2_HUMAN (Q04721) Neurogenic locus notch homolog protein 2 precursor (Notch 2)| (hN2) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain] Length = 2471 Score = 53.9 bits (128), Expect = 4e-07 Identities = 31/97 (31%), Positives = 49/97 (50%) Frame = -1 Query: 504 ADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVD 325 AD + D G+ ALH+A + +LL+ GA D D + TPL AA G E Sbjct: 1968 ADVNAVDDHGKSALHWAAAVNNVEATLLLLKNGANRDMQDNKEETPLFLAAREGSYEAAK 2027 Query: 324 LLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLLEK 214 +LL H A + + + P DVA+ ++++LL++ Sbjct: 2028 ILLDHFANRDITDHMDRLPRDVARDRMHHDIVRLLDE 2064 Score = 45.1 bits (105), Expect = 2e-04 Identities = 38/149 (25%), Positives = 58/149 (38%), Gaps = 34/149 (22%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLE--------- 412 +H A + K+ LD GAD + +D+ GR LH A +IL+ Sbjct: 1881 LHLAARYSRADAAKRLLDAGADANAQDNMGRCPLHAAVAADAQGVFQILIRNRVTDLDAR 1940 Query: 411 -------------------------AGAAVDAMDKNKNTPLHYAAGYGRKECVDLLLKHG 307 A V+A+D + + LH+AA E LLLK+G Sbjct: 1941 MNDGTTPLILAARLAVEGMVAELINCQADVNAVDDHGKSALHWAAAVNNVEATLLLLKNG 2000 Query: 306 AAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 A +Q+ +TP+ +A E K+L Sbjct: 2001 ANRDMQDNKEETPLFLAAREGSYEAAKIL 2029 Score = 42.4 bits (98), Expect = 0.001 Identities = 26/86 (30%), Positives = 41/86 (47%), Gaps = 1/86 (1%) Frame = -1 Query: 510 GGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKEC 331 G + + + D G ALH A Y A+ LL+AGA +A D PLH A + Sbjct: 1866 GASLQAQTDRTGEMALHLAARYSRADAAKRLLDAGADANAQDNMGRCPLHAAVAADAQGV 1925 Query: 330 VDLLLKHGAA-VTLQNMDGKTPIDVA 256 +L+++ + + DG TP+ +A Sbjct: 1926 FQILIRNRVTDLDARMNDGTTPLILA 1951
>ASB2_MOUSE (Q8K0L0) Ankyrin repeat and SOCS box protein 2 (ASB-2)| Length = 634 Score = 53.9 bits (128), Expect = 4e-07 Identities = 32/107 (29%), Positives = 53/107 (49%) Frame = -1 Query: 540 DGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLH 361 + E ++ + AD + + G ALH + + + EIL+ GA V+A + TPL Sbjct: 217 NAEAVRILVRYNADANHRCNRGWTALHESVSRNDLEVMEILVSGGAKVEAKNVYSITPLF 276 Query: 360 YAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 AA G+ E + L KHGA + Q D + + A N ++V++ L Sbjct: 277 VAAQSGQLEALRFLAKHGADINTQASDSASALYEASKNEHEDVVEFL 323 Score = 48.9 bits (115), Expect = 1e-05 Identities = 32/109 (29%), Positives = 51/109 (46%), Gaps = 1/109 (0%) Frame = -1 Query: 543 GDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEA-GAAVDAMDKNKNTP 367 GD E LK + G + E + EG LH A YG+ C ++L +A +D + T Sbjct: 116 GDEEALKIMIQDGKNLAEPNKEGWLPLHEAAYYGQLGCLKVLQQAYPGTIDQRTLQEETA 175 Query: 366 LHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 L+ A +C+ LL+ GA + N +TP+ A E +++L Sbjct: 176 LYLATCREHLDCLLSLLQAGAEPDISNKSRETPLYKACERKNAEAVRIL 224 Score = 29.6 bits (65), Expect = 8.5 Identities = 25/65 (38%), Positives = 33/65 (50%), Gaps = 4/65 (6%) Frame = -1 Query: 480 EGRR--ALHFACGYGEFKCAEILLEAGAAVDAMDKNKN--TPLHYAAGYGRKECVDLLLK 313 E RR AL+FA E+LL AGA D N++ +PL A +G + LLL Sbjct: 408 EDRRSSALYFAVVNNNVYATELLLLAGA-----DPNRDVISPLLVAIRHGCLRTMQLLLD 462 Query: 312 HGAAV 298 HGA + Sbjct: 463 HGANI 467
>ASB11_MOUSE (Q9CQ31) Ankyrin repeat and SOCS box protein 11 (ASB-11)| Length = 323 Score = 53.9 bits (128), Expect = 4e-07 Identities = 34/105 (32%), Positives = 54/105 (51%) Frame = -1 Query: 570 SIVHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDA 391 S +H G E ++ L + ++E + L+ AC Y C + LLE GA+VD Sbjct: 165 SPIHEAVKRGHRECMEILLTKDVNIEQEVPQLGTPLYVACTYQRVDCVKKLLELGASVDH 224 Query: 390 MDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVA 256 + +TPLH A E ++LL +GA + L+N GK+ +D+A Sbjct: 225 -GQWLDTPLHAAVRQSSVEVINLLTVYGANLNLRNAQGKSALDLA 268 Score = 50.8 bits (120), Expect = 4e-06 Identities = 39/121 (32%), Positives = 57/121 (47%) Frame = -1 Query: 570 SIVHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDA 391 S +H A+ G LK + G + + +LH AC G CA+ LLE GA V+A Sbjct: 67 SPLHEAAAQGRLLALKTLIAQGINVNLVTINRVSSLHEACLGGHVACAKALLENGAHVNA 126 Query: 390 MDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLLEKD 211 + TPL A G CV++LL+ GA L+ + K +++ + LL KD Sbjct: 127 QTVHGATPLFNACCSGSAACVNVLLEFGAKAQLEIYLASPIHEAVKRGHRECMEILLTKD 186 Query: 210 V 208 V Sbjct: 187 V 187 Score = 47.0 bits (110), Expect = 5e-05 Identities = 37/116 (31%), Positives = 53/116 (45%), Gaps = 2/116 (1%) Frame = -1 Query: 558 HTASVGDGEGLKKAL-DGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDK 382 H A +G KAL + GA + + G L AC G C +LLE GA ++ Sbjct: 103 HEACLGGHVACAKALLENGAHVNAQTVHGATPLFNACCSGSAACVNVLLEFGAKAQ-LEI 161 Query: 381 NKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVA-KLNNQDEVLKLLE 217 +P+H A G +EC+++LL + + TP+ VA D V KLLE Sbjct: 162 YLASPIHEAVKRGHRECMEILLTKDVNIEQEVPQLGTPLYVACTYQRVDCVKKLLE 217 Score = 41.6 bits (96), Expect = 0.002 Identities = 30/83 (36%), Positives = 42/83 (50%), Gaps = 1/83 (1%) Frame = -1 Query: 465 LHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTL-Q 289 +H A G +C EILL ++ TPL+ A Y R +CV LL+ GA+V Q Sbjct: 167 IHEAVKRGHRECMEILLTKDVNIEQEVPQLGTPLYVACTYQRVDCVKKLLELGASVDHGQ 226 Query: 288 NMDGKTPIDVAKLNNQDEVLKLL 220 +D TP+ A + EV+ LL Sbjct: 227 WLD--TPLHAAVRQSSVEVINLL 247
>ASZ1_HORSE (Q2QLA4) Ankyrin repeat, SAM and basic leucine zipper| domain-containing protein 1 (Germ cell-specific ankyrin, SAM and basic leucine zipper domain-containing protein) Length = 475 Score = 53.5 bits (127), Expect = 5e-07 Identities = 43/120 (35%), Positives = 63/120 (52%), Gaps = 6/120 (5%) Frame = -1 Query: 558 HTASVGDGEGLKKALDGGADKDEEDSEGRRALHFAC---GYGE--FKCAEILLEAGAAVD 394 + ASV + + ++ LD GA K D + + L AC G E KC E+LL A + Sbjct: 85 YAASVSNVDLVRVLLDRGA-KASFDKDKQTILITACSARGSEEQILKCVELLLSRNADPN 143 Query: 393 AMDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPID-VAKLNNQDEVLKLLE 217 + TP+ YAA G + V LL+ HGA V Q+ +G T + A+ +++ VLKLLE Sbjct: 144 VACRRLMTPIMYAARDGHPQVVALLVAHGAEVNTQDENGYTALTWAARQGHKNVVLKLLE 203 Score = 52.0 bits (123), Expect = 2e-06 Identities = 31/80 (38%), Positives = 42/80 (52%) Frame = -1 Query: 459 FACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMD 280 +A G + +L+ GA V+ D+N T L +AA G K V LL+ GA LQ D Sbjct: 155 YAARDGHPQVVALLVAHGAEVNTQDENGYTALTWAARQGHKNVVLKLLELGANKMLQTKD 214 Query: 279 GKTPIDVAKLNNQDEVLKLL 220 GKTP ++AK N E+ L Sbjct: 215 GKTPSEIAKRNKHLEIFNFL 234 Score = 35.4 bits (80), Expect = 0.15 Identities = 31/105 (29%), Positives = 50/105 (47%), Gaps = 5/105 (4%) Frame = -1 Query: 516 LDGGADKDEED---SEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGY 346 LD A K +E E A G+ E LL++G +VD+ + TPL YAA Sbjct: 30 LDRAAQKLKEPLPIEEKNETFKRALTAGDVALVEELLDSGISVDSSFRYGWTPLMYAASV 89 Query: 345 GRKECVDLLLKHGAAVTLQNMDGKTPIDVA--KLNNQDEVLKLLE 217 + V +LL GA + + D +T + A +++++LK +E Sbjct: 90 SNVDLVRVLLDRGAKASF-DKDKQTILITACSARGSEEQILKCVE 133 Score = 31.6 bits (70), Expect = 2.2 Identities = 27/96 (28%), Positives = 42/96 (43%) Frame = -1 Query: 507 GADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECV 328 GA+ + +D G AL +A G LLE GA K+ TP A E Sbjct: 172 GAEVNTQDENGYTALTWAARQGHKNVVLKLLELGANKMLQTKDGKTPSEIAKRNKHLEIF 231 Query: 327 DLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 + L ++TL ++GK + +L ++ + KLL Sbjct: 232 NFL-----SLTLNPLEGK----LQQLTKEETICKLL 258
>ASZ1_BOVIN (Q8WMX8) Ankyrin repeat, SAM and basic leucine zipper| domain-containing protein 1 (Germ cell-specific ankyrin, SAM and basic leucine zipper domain-containing protein) Length = 475 Score = 53.5 bits (127), Expect = 5e-07 Identities = 43/120 (35%), Positives = 63/120 (52%), Gaps = 6/120 (5%) Frame = -1 Query: 558 HTASVGDGEGLKKALDGGADKDEEDSEGRRALHFAC---GYGE--FKCAEILLEAGAAVD 394 + ASV + E ++ LD GA+ D + + L AC G E KC E+LL A + Sbjct: 85 YAASVSNVELVRVLLDRGANASF-DKDKQTVLITACSARGSEEKILKCIELLLSRNADPN 143 Query: 393 AMDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPID-VAKLNNQDEVLKLLE 217 + TP+ YAA G + V LL+ HGA V Q+ +G T + A+ +++ VLKLLE Sbjct: 144 VACRRLMTPIMYAARDGHPQVVALLVAHGAEVNTQDENGYTALTWAARQGHKNVVLKLLE 203 Score = 51.2 bits (121), Expect = 3e-06 Identities = 30/80 (37%), Positives = 42/80 (52%) Frame = -1 Query: 459 FACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMD 280 +A G + +L+ GA V+ D+N T L +AA G K V LL+ GA +Q D Sbjct: 155 YAARDGHPQVVALLVAHGAEVNTQDENGYTALTWAARQGHKNVVLKLLELGANKMIQTKD 214 Query: 279 GKTPIDVAKLNNQDEVLKLL 220 GKTP ++AK N E+ L Sbjct: 215 GKTPSEIAKRNKHLEIFNFL 234 Score = 33.5 bits (75), Expect = 0.59 Identities = 28/99 (28%), Positives = 43/99 (43%) Frame = -1 Query: 507 GADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECV 328 GA+ + +D G AL +A G LLE GA K+ TP A E Sbjct: 172 GAEVNTQDENGYTALTWAARQGHKNVVLKLLELGANKMIQTKDGKTPSEIAKRNKHLEIF 231 Query: 327 DLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLLEKD 211 + L ++TL ++GK + +L ++ + KLL D Sbjct: 232 NFL-----SLTLNPLEGK----LHQLTKEESICKLLRTD 261
>HOS4_YEAST (P40480) Protein HOS4| Length = 1083 Score = 53.5 bits (127), Expect = 5e-07 Identities = 34/97 (35%), Positives = 56/97 (57%), Gaps = 3/97 (3%) Frame = -1 Query: 543 GDGEGLKKALD-GGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVD--AMDKNKN 373 G + +KK ++ GG D +++D+ G ALH A G + E+L+E GA V+ +++ + Sbjct: 341 GKYDVVKKMIEEGGYDINDQDNAGNTALHEAALQGHIEIVELLIENGADVNIKSIEMFGD 400 Query: 372 TPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPID 262 TPL A+ G + V LLK+GA T++N G T + Sbjct: 401 TPLIDASANGHLDVVKYLLKNGADPTIRNAKGLTAFE 437 Score = 32.0 bits (71), Expect = 1.7 Identities = 27/88 (30%), Positives = 43/88 (48%), Gaps = 6/88 (6%) Frame = -1 Query: 453 CGYGEFKCAEILLEAGAAVDAMDK-NKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDG 277 CG+ + I L G V+ + NK + L A G G V LLL+ GA T ++ G Sbjct: 570 CGHEDI--TSIFLAFGFPVNQTSRDNKTSALMVAVGRGHLGTVKLLLEAGADPTKRDKKG 627 Query: 276 KTPIDVAK-----LNNQDEVLKLLEKDV 208 +T + AK + N +E+ +L+E + Sbjct: 628 RTALYYAKNSIMGITNSEEI-QLIENAI 654 Score = 30.8 bits (68), Expect = 3.8 Identities = 17/38 (44%), Positives = 20/38 (52%) Frame = -1 Query: 468 ALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYA 355 AL A G G ++LLEAGA DK T L+YA Sbjct: 597 ALMVAVGRGHLGTVKLLLEAGADPTKRDKKGRTALYYA 634
>ASB1_MOUSE (Q9WV74) Ankyrin repeat and SOCS box protein 1 (ASB-1)| Length = 336 Score = 53.5 bits (127), Expect = 5e-07 Identities = 29/89 (32%), Positives = 52/89 (58%) Frame = -1 Query: 552 ASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKN 373 A+ G G + + GA+ D D +G+ AL+ A G + EILLEAGA + +++ Sbjct: 87 ATAGHGNCVDFLIRKGAEVDLVDVKGQTALYVAVVNGHLESTEILLEAGADPNGSRHHRS 146 Query: 372 TPLHYAAGYGRKECVDLLLKHGAAVTLQN 286 TP+++A+ GR + + L+++GA V + + Sbjct: 147 TPVYHASRVGRDDILKALIRYGADVDVNH 175 Score = 43.9 bits (102), Expect = 4e-04 Identities = 33/123 (26%), Positives = 51/123 (41%), Gaps = 8/123 (6%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGR--------RALHFACGYGEFKCAEILLEA 409 +H A VGD + L+ L + + + + L A G C + L+ Sbjct: 42 LHDAAYVGDLQTLRNLLQEESYRSRINEKSVWCCGWLPCTPLRIAATAGHGNCVDFLIRK 101 Query: 408 GAAVDAMDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVL 229 GA VD +D T L+ A G E ++LL+ GA TP+ A +D++L Sbjct: 102 GAEVDLVDVKGQTALYVAVVNGHLESTEILLEAGADPNGSRHHRSTPVYHASRVGRDDIL 161 Query: 228 KLL 220 K L Sbjct: 162 KAL 164 Score = 33.5 bits (75), Expect = 0.59 Identities = 32/103 (31%), Positives = 45/103 (43%), Gaps = 17/103 (16%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGAD--------KDEEDSEGRR-------ALHFACGYGEFKC 430 V+H + VG + LK + GAD D RR L+ + Y +C Sbjct: 149 VYHASRVGRDDILKALIRYGADVDVNHHLTPDTRPPFSRRLTSLVVCPLYISAAYHNLQC 208 Query: 429 AEILLEAGAAVDAMDKNKNTPLHYAAGY-GRKECV-DLLLKHG 307 +LL+AGA D N N P++ Y G CV D +L+HG Sbjct: 209 FRLLLQAGANPDF---NCNGPVNTQEFYRGSPGCVMDAVLRHG 248
>ANKS1_MOUSE (P59672) Ankyrin repeat and SAM domain-containing protein 1A| Length = 1149 Score = 53.5 bits (127), Expect = 5e-07 Identities = 39/139 (28%), Positives = 63/139 (45%), Gaps = 24/139 (17%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAA----- 400 +HH A G + ++ L A + DS+G LH A G+ + +L++ G + Sbjct: 79 LHHAALNGHRDVVEVLLRNDALTNVADSKGCYPLHLAAWKGDAQIVRLLIQQGPSHTRVN 138 Query: 399 -------------------VDAMDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDG 277 ++A + + T LH AA YG E V LL+ T++N Sbjct: 139 EQNALEIRELKKYGPFDPYINAKNNDNETALHCAAQYGHTEVVKALLEELTDPTMRNNKF 198 Query: 276 KTPIDVAKLNNQDEVLKLL 220 +TP+D+A L + EV+KLL Sbjct: 199 ETPLDLAALYGRLEVVKLL 217 Score = 44.7 bits (104), Expect = 3e-04 Identities = 34/115 (29%), Positives = 48/115 (41%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMD 385 +H A G E +K L+ D +++ L A YG + ++LL A + + Sbjct: 169 LHCAAQYGHTEVVKALLEELTDPTMRNNKFETPLDLAALYGRLEVVKLLLGAHPNLLSCS 228 Query: 384 KNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 K+TPLH AA G K V +LL G Q G + A D V LL Sbjct: 229 TRKHTPLHLAARNGHKAVVQVLLDAGMDSNYQTEMGSALHEAALFGKTDVVQILL 283 Score = 41.2 bits (95), Expect = 0.003 Identities = 31/92 (33%), Positives = 45/92 (48%), Gaps = 2/92 (2%) Frame = -1 Query: 489 EDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLLKH 310 ++++ ALH A YG + + LLE + TPL AA YGR E V LLL Sbjct: 161 KNNDNETALHCAAQYGHTEVVKALLEELTDPTMRNNKFETPLDLAALYGRLEVVKLLL-- 218 Query: 309 GAAVTLQNMDGK--TPIDVAKLNNQDEVLKLL 220 GA L + + TP+ +A N V+++L Sbjct: 219 GAHPNLLSCSTRKHTPLHLAARNGHKAVVQVL 250 Score = 40.0 bits (92), Expect = 0.006 Identities = 19/63 (30%), Positives = 36/63 (57%) Frame = -1 Query: 408 GAAVDAMDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVL 229 G V+ +D TPLH+AA G ++ V++LL++ A + + G P+ +A +++ Sbjct: 65 GPNVNCVDSTGYTPLHHAALNGHRDVVEVLLRNDALTNVADSKGCYPLHLAAWKGDAQIV 124 Query: 228 KLL 220 +LL Sbjct: 125 RLL 127 Score = 37.4 bits (85), Expect = 0.041 Identities = 24/67 (35%), Positives = 30/67 (44%) Frame = -1 Query: 486 DSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLLKHG 307 DS G LH A G E+LL A + D PLH AA G + V LL++ G Sbjct: 72 DSTGYTPLHHAALNGHRDVVEVLLRNDALTNVADSKGCYPLHLAAWKGDAQIVRLLIQQG 131 Query: 306 AAVTLQN 286 + T N Sbjct: 132 PSHTRVN 138 Score = 30.4 bits (67), Expect = 5.0 Identities = 22/67 (32%), Positives = 31/67 (46%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMD 385 +H A G ++ LD G D + + G ALH A +G+ +ILL AG V+ D Sbjct: 235 LHLAARNGHKAVVQVLLDAGMDSNYQTEMGS-ALHEAALFGKTDVVQILLAAGIDVNIKD 293 Query: 384 KNKNTPL 364 T L Sbjct: 294 NRGLTAL 300
>ASB2_RAT (Q5U2S6) Ankyrin repeat and SOCS box protein 2 (ASB-2)| Length = 634 Score = 53.5 bits (127), Expect = 5e-07 Identities = 32/107 (29%), Positives = 53/107 (49%) Frame = -1 Query: 540 DGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLH 361 + E ++ + AD + + G ALH + + + EIL+ GA V+A + TPL Sbjct: 217 NAEAVRILVQYNADANHRCNRGWTALHESVSRNDLEVMEILVSGGAKVEAKNVYSITPLF 276 Query: 360 YAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 AA G+ E + L KHGA + Q D + + A N ++V++ L Sbjct: 277 VAAQSGQLEALRFLAKHGADINTQASDSASALYEACKNEHEDVVEFL 323 Score = 48.5 bits (114), Expect = 2e-05 Identities = 32/109 (29%), Positives = 50/109 (45%), Gaps = 1/109 (0%) Frame = -1 Query: 543 GDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEA-GAAVDAMDKNKNTP 367 GD E LK + G + E + EG LH A YG+ C ++L A +D + T Sbjct: 116 GDEEALKAMIQDGKNLAEPNKEGWLPLHEAAYYGKLGCLKVLQRAYPGTIDQRTLQEETA 175 Query: 366 LHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 L+ A +C+ LL+ GA + N +TP+ A E +++L Sbjct: 176 LYLATCREHLDCLLSLLQAGAEPDISNKSRETPLYKACERKNAEAVRIL 224 Score = 29.6 bits (65), Expect = 8.5 Identities = 25/65 (38%), Positives = 33/65 (50%), Gaps = 4/65 (6%) Frame = -1 Query: 480 EGRR--ALHFACGYGEFKCAEILLEAGAAVDAMDKNKN--TPLHYAAGYGRKECVDLLLK 313 E RR AL+FA E+LL AGA D N++ +PL A +G + LLL Sbjct: 408 EDRRTSALYFAVVNNNVYATELLLLAGA-----DPNRDVISPLLVAIRHGCLRTMQLLLD 462 Query: 312 HGAAV 298 HGA + Sbjct: 463 HGANI 467
>AKR1_ASPFU (Q4X251) Palmitoyltransferase akr1 (EC 2.3.1.-) (Ankyrin| repeat-containing protein akr1) Length = 738 Score = 53.5 bits (127), Expect = 5e-07 Identities = 32/88 (36%), Positives = 44/88 (50%) Frame = -1 Query: 495 DEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLL 316 D D +G L +A G C ++ L GA V+A+D TPLH+A G CV L+ Sbjct: 191 DVIDQQGHTGLMWAAYKGYPACVDLFLRWGANVNAVDDGGLTPLHWALVKGSLPCVQKLI 250 Query: 315 KHGAAVTLQNMDGKTPIDVAKLNNQDEV 232 ++GA + DGK+P VA N V Sbjct: 251 EYGADRFAKTRDGKSPATVAGEMNTTRV 278 Score = 46.2 bits (108), Expect = 9e-05 Identities = 31/84 (36%), Positives = 40/84 (47%) Frame = -1 Query: 516 LDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRK 337 L GAD D +G LH A G +LL VD +D+ +T L +AA G Sbjct: 151 LQHGADPLLTDVQGYNILHLATIDGNAFLLVLLLHQEIPVDVIDQQGHTGLMWAAYKGYP 210 Query: 336 ECVDLLLKHGAAVTLQNMDGKTPI 265 CVDL L+ GA V + G TP+ Sbjct: 211 ACVDLFLRWGANVNAVDDGGLTPL 234 Score = 40.4 bits (93), Expect = 0.005 Identities = 29/91 (31%), Positives = 46/91 (50%), Gaps = 1/91 (1%) Frame = -1 Query: 489 EDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNK-NTPLHYAAGYGRKECVDLLLK 313 +D EG LH+A ++ + LL+ GA V+A + TP +AA V LLL+ Sbjct: 93 QDEEGITPLHWAAINNQYAMCKFLLDNGADVNAKGGDSVATPAMWAAQRCHYYIVHLLLQ 152 Query: 312 HGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 HGA L ++ G + +A ++ +L LL Sbjct: 153 HGADPLLTDVQGYNILHLATIDGNAFLLVLL 183
>NOTC1_HUMAN (P46531) Neurogenic locus notch homolog protein 1 precursor (Notch 1)| (hN1) (Translocation-associated notch protein TAN-1) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain] Length = 2556 Score = 53.1 bits (126), Expect = 7e-07 Identities = 31/105 (29%), Positives = 53/105 (50%) Frame = -1 Query: 528 LKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAG 349 L+ ++ AD + D G+ ALH+A A +LL+ GA D + + TPL AA Sbjct: 2012 LEDLINSHADVNAVDDLGKSALHWAAAVNNVDAAVVLLKNGANKDMQNNREETPLFLAAR 2071 Query: 348 YGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLLEK 214 G E +LL H A + + + P D+A+ ++++LL++ Sbjct: 2072 EGSYETAKVLLDHFANRDITDHMDRLPRDIAQERMHHDIVRLLDE 2116 Score = 43.9 bits (102), Expect = 4e-04 Identities = 33/115 (28%), Positives = 52/115 (45%), Gaps = 2/115 (1%) Frame = -1 Query: 558 HTASVGDGEGLKKAL--DGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMD 385 H A D +G+ + L + D D +G L A E L+ + A V+A+D Sbjct: 1967 HAAVSADAQGVFQILIRNRATDLDARMHDGTTPLILAARLAVEGMLEDLINSHADVNAVD 2026 Query: 384 KNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 + LH+AA + +LLK+GA +QN +TP+ +A E K+L Sbjct: 2027 DLGKSALHWAAAVNNVDAAVVLLKNGANKDMQNNREETPLFLAAREGSYETAKVL 2081 Score = 43.5 bits (101), Expect = 6e-04 Identities = 27/86 (31%), Positives = 41/86 (47%), Gaps = 1/86 (1%) Frame = -1 Query: 510 GGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKEC 331 G + ++ D G ALH A Y A+ LLEA A + D TPLH A + Sbjct: 1918 GASLHNQTDRTGETALHLAARYSRSDAAKRLLEASADANIQDNMGRTPLHAAVSADAQGV 1977 Query: 330 VDLLLKHGAA-VTLQNMDGKTPIDVA 256 +L+++ A + + DG TP+ +A Sbjct: 1978 FQILIRNRATDLDARMHDGTTPLILA 2003 Score = 35.4 bits (80), Expect = 0.15 Identities = 18/70 (25%), Positives = 34/70 (48%) Frame = -1 Query: 429 AEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKL 250 ++ + + + + D+ T LH AA Y R + LL+ A +Q+ G+TP+ A Sbjct: 1912 SDFIYQGASLHNQTDRTGETALHLAARYSRSDAAKRLLEASADANIQDNMGRTPLHAAVS 1971 Query: 249 NNQDEVLKLL 220 + V ++L Sbjct: 1972 ADAQGVFQIL 1981
>PSDA_YEAST (P50086) Probable 26S proteasome regulatory subunit p28 (Proteasome| non-ATPase subunit 6) Length = 228 Score = 53.1 bits (126), Expect = 7e-07 Identities = 41/120 (34%), Positives = 60/120 (50%), Gaps = 4/120 (3%) Frame = -1 Query: 561 HHTASVGDGEGLKKALDGGA--DKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAM 388 H SVG+ E +K D D ++ ++G LH A G F+ ++ L+E GA+V Sbjct: 77 HIACSVGNLEVVKSLYDRPLKPDLNKITNQGVTCLHLAVGKKWFEVSQFLIENGASVRIK 136 Query: 387 DKNKNTPLHYAAGYGRKECVDLLLKHG-AAVTLQNMDGKTPIDVAKLNNQ-DEVLKLLEK 214 DK PLH AA G + ++LL G +AV Q+ G TP+ A D + L+EK Sbjct: 137 DKFNQIPLHRAASVGSLKLIELLCGLGKSAVNWQDKQGWTPLFHALAEGHGDAAVLLVEK 196
>V023_FOWPV (Q9J5H8) Putative ankyrin repeat protein FPV023| Length = 434 Score = 53.1 bits (126), Expect = 7e-07 Identities = 39/107 (36%), Positives = 57/107 (53%), Gaps = 4/107 (3%) Frame = -1 Query: 516 LDGGADKDEEDSE--GRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAA-GY 346 LD GAD + S G + LH A G G F A+ L+E+GA + DK TPLH AA Sbjct: 222 LDSGADPNSSSSSSIGTKVLHTAVGSGNFNIAKELIESGADPNIGDKAGVTPLHVAAIDE 281 Query: 345 GRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLN-NQDEVLKLLEKDV 208 ++LLL +GA ++ +G TP+ A N N+ ++L + D+ Sbjct: 282 DSYALLELLLDNGADPNIKCSNGTTPLFQAMHNYNRVKLLFMYGADI 328 Score = 42.4 bits (98), Expect = 0.001 Identities = 38/154 (24%), Positives = 68/154 (44%), Gaps = 2/154 (1%) Frame = -1 Query: 567 IVHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFAC-GYGEFKCAEILLEAGAAVDA 391 ++H G+ K+ ++ GAD + D G LH A + E+LL+ GA + Sbjct: 240 VLHTAVGSGNFNIAKELIESGADPNIGDKAGVTPLHVAAIDEDSYALLELLLDNGADPNI 299 Query: 390 MDKNKNTPLHYAA-GYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLLEK 214 N TPL A Y R V LL +GA + + + G TP + +++ ++ Sbjct: 300 KCSNGTTPLFQAMHNYNR---VKLLFMYGADINIIDNQGNTPFTNLMSYDNEKLNSIIIL 356 Query: 213 DVFL*IASLGSHEETWPSSCFTSLWHWLDSHTRI 112 + L I L + + +P+ +L ++SH + Sbjct: 357 QIML-IRKLFNDKMYYPAGLIKNL-ECIESHENL 388 Score = 41.2 bits (95), Expect = 0.003 Identities = 25/75 (33%), Positives = 38/75 (50%), Gaps = 1/75 (1%) Frame = -1 Query: 441 EFKCAEILLEAGAAVDAMDKNKNTPLHYAAGY-GRKECVDLLLKHGAAVTLQNMDGKTPI 265 E + +ILL G ++ D NT LHYA Y V L+K+GA + ++N G TP+ Sbjct: 147 EIQIMDILLSKGIDINFKDDIGNTALHYACDYRNGLNMVRHLIKNGADINIENDYGTTPL 206 Query: 264 DVAKLNNQDEVLKLL 220 A E++ +L Sbjct: 207 ACAVSTRNIELVSIL 221 Score = 38.5 bits (88), Expect = 0.018 Identities = 37/159 (23%), Positives = 67/159 (42%), Gaps = 3/159 (1%) Frame = -1 Query: 564 VHHTASVGDGEGLKKAL-DGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAM 388 +H+ +G + + L GAD + E+ G L A + ILL++GA ++ Sbjct: 172 LHYACDYRNGLNMVRHLIKNGADINIENDYGTTPLACAVSTRNIELVSILLDSGADPNSS 231 Query: 387 DKNK--NTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLLEK 214 + LH A G G L++ GA + + G TP+ VA ++ L L Sbjct: 232 SSSSIGTKVLHTAVGSGNFNIAKELIESGADPNIGDKAGVTPLHVAAIDEDSYALLEL-- 289 Query: 213 DVFL*IASLGSHEETWPSSCFTSLWHWLDSHTRIGILFV 97 + G+ S+ T L+ + ++ R+ +LF+ Sbjct: 290 -----LLDNGADPNIKCSNGTTPLFQAMHNYNRVKLLFM 323 Score = 36.2 bits (82), Expect = 0.091 Identities = 24/72 (33%), Positives = 33/72 (45%), Gaps = 1/72 (1%) Frame = -1 Query: 516 LDGGADKDEEDSEGRRALHFACGY-GEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGR 340 L G D + +D G ALH+AC Y L++ GA ++ + TPL A Sbjct: 155 LSKGIDINFKDDIGNTALHYACDYRNGLNMVRHLIKNGADINIENDYGTTPLACAVSTRN 214 Query: 339 KECVDLLLKHGA 304 E V +LL GA Sbjct: 215 IELVSILLDSGA 226
>DDFL1_HUMAN (Q8TDY4) Development and differentiation enhancing factor-like 1| (Protein up-regulated in liver cancer 1) Length = 903 Score = 53.1 bits (126), Expect = 7e-07 Identities = 27/71 (38%), Positives = 43/71 (60%) Frame = -1 Query: 426 EILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLN 247 + +++ G +DA + NT LHYAA Y + +C+ LLLK A V N G+T +D+A+ Sbjct: 606 DFIIQNGGHLDAKAADGNTALHYAALYNQPDCLKLLLKGRALVGTVNEAGETALDIARKK 665 Query: 246 NQDEVLKLLEK 214 + E +LLE+ Sbjct: 666 HHKECEELLEQ 676 Score = 30.8 bits (68), Expect = 3.8 Identities = 15/39 (38%), Positives = 23/39 (58%) Frame = -1 Query: 330 VDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLLEK 214 VD ++++G + + DG T + A L NQ + LKLL K Sbjct: 605 VDFIIQNGGHLDAKAADGNTALHYAALYNQPDCLKLLLK 643
>NOTC1_RAT (Q07008) Neurogenic locus notch homolog protein 1 precursor (Notch 1)| [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain] Length = 2531 Score = 53.1 bits (126), Expect = 7e-07 Identities = 31/105 (29%), Positives = 53/105 (50%) Frame = -1 Query: 528 LKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAG 349 L+ ++ AD + D G+ ALH+A A +LL+ GA D + + TPL AA Sbjct: 2001 LEDLINSHADVNAVDDLGKSALHWAAAVNNVDAAVVLLKNGANKDMQNNKEETPLFLAAR 2060 Query: 348 YGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLLEK 214 G E +LL H A + + + P D+A+ ++++LL++ Sbjct: 2061 EGSYETAKVLLDHFANRDITDHMDRLPRDIAQERMHHDIVRLLDE 2105 Score = 44.3 bits (103), Expect = 3e-04 Identities = 33/115 (28%), Positives = 52/115 (45%), Gaps = 2/115 (1%) Frame = -1 Query: 558 HTASVGDGEGLKKAL--DGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMD 385 H A D +G+ + L + D D +G L A E L+ + A V+A+D Sbjct: 1956 HAAVSADAQGVFQILLRNRATDLDARMHDGTTPLILAARLAVEGMLEDLINSHADVNAVD 2015 Query: 384 KNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 + LH+AA + +LLK+GA +QN +TP+ +A E K+L Sbjct: 2016 DLGKSALHWAAAVNNVDAAVVLLKNGANKDMQNNKEETPLFLAAREGSYETAKVL 2070 Score = 44.3 bits (103), Expect = 3e-04 Identities = 28/86 (32%), Positives = 41/86 (47%), Gaps = 1/86 (1%) Frame = -1 Query: 510 GGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKEC 331 G + ++ D G ALH A Y A+ LLEA A + D TPLH A + Sbjct: 1907 GASLHNQTDRTGETALHLAARYSRSDAAKRLLEASADANIQDNMGRTPLHAAVSADAQGV 1966 Query: 330 VDLLLKHGAA-VTLQNMDGKTPIDVA 256 +LL++ A + + DG TP+ +A Sbjct: 1967 FQILLRNRATDLDARMHDGTTPLILA 1992 Score = 35.4 bits (80), Expect = 0.15 Identities = 18/70 (25%), Positives = 34/70 (48%) Frame = -1 Query: 429 AEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKL 250 ++ + + + + D+ T LH AA Y R + LL+ A +Q+ G+TP+ A Sbjct: 1901 SDFIYQGASLHNQTDRTGETALHLAARYSRSDAAKRLLEASADANIQDNMGRTPLHAAVS 1960 Query: 249 NNQDEVLKLL 220 + V ++L Sbjct: 1961 ADAQGVFQIL 1970
>AKR1_YARLI (Q6C520) Palmitoyltransferase AKR1 (EC 2.3.1.-) (Ankyrin| repeat-containing protein AKR1) Length = 702 Score = 53.1 bits (126), Expect = 7e-07 Identities = 33/102 (32%), Positives = 50/102 (49%), Gaps = 1/102 (0%) Frame = -1 Query: 516 LDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRK 337 + GAD D +G ALH A LL G VD D N T LH+AA G Sbjct: 138 IQNGADPLRSDVQGYNALHLATHSSNVMLLVYLLHQGLPVDCQDPNGRTALHWAAYQGDA 197 Query: 336 ECVDLLLKHGAAVTLQNMDGKTPIDVAKLN-NQDEVLKLLEK 214 VD+LL+ G+ V + + G P+ +N +++ + +L+E+ Sbjct: 198 LSVDVLLRWGSDVKITDTQGFLPLHWGIVNGSRNSLARLIEE 239 Score = 49.3 bits (116), Expect = 1e-05 Identities = 29/91 (31%), Positives = 47/91 (51%), Gaps = 1/91 (1%) Frame = -1 Query: 516 LDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRK 337 L G D +D GR ALH+A G+ ++LL G+ V D PLH+ G + Sbjct: 171 LHQGLPVDCQDPNGRTALHWAAYQGDALSVDVLLRWGSDVKITDTQGFLPLHWGIVNGSR 230 Query: 336 ECVDLLLKHGAAVTLQNMDGKTP-IDVAKLN 247 + L++ G+ + ++ DGKTP + A++N Sbjct: 231 NSLARLIEEGSDMYAKSSDGKTPHVMAAEMN 261 Score = 39.7 bits (91), Expect = 0.008 Identities = 29/98 (29%), Positives = 47/98 (47%), Gaps = 2/98 (2%) Frame = -1 Query: 543 GDGEGLKKALDGGADKDEEDSE-GRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKN-T 370 G+ +K+ + G+ + +E G ALH+A + L+E GA VDA N T Sbjct: 61 GNTAEVKRLCESGSYSVLDTAEDGVTALHWAAVNNRISTCQYLVEQGAVVDAKGGQLNGT 120 Query: 369 PLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVA 256 PLH+A G V L+++GA ++ G + +A Sbjct: 121 PLHWACRRGLVYIVHYLIQNGADPLRSDVQGYNALHLA 158
>POTE2_HUMAN (Q6S8J3) Prostate, ovary, testis expressed protein on chromosome 2| (Fragment) Length = 712 Score = 53.1 bits (126), Expect = 7e-07 Identities = 38/117 (32%), Positives = 58/117 (49%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMD 385 +H ++ G+ E +K LD + D++ R AL A E +CA +LLE G + D Sbjct: 177 LHLASANGNSEVVKLLLDRRCQLNVLDNKKRTALIKAVQCQEDECALMLLEHGTDPNIPD 236 Query: 384 KNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLLEK 214 + NT LHYA K LL +GA + +N G TP+ + + +V+K L K Sbjct: 237 EYGNTTLHYAIYNEDKLMAKALLLYGADIESKNKHGLTPLLLGVHEQKQQVVKFLIK 293 Score = 47.0 bits (110), Expect = 5e-05 Identities = 26/91 (28%), Positives = 47/91 (51%) Frame = -1 Query: 501 DKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDL 322 D +++D + R ALH A G + ++LL+ ++ +D K T L A EC + Sbjct: 165 DVNKKDKQKRTALHLASANGNSEVVKLLLDRRCQLNVLDNKKRTALIKAVQCQEDECALM 224 Query: 321 LLKHGAAVTLQNMDGKTPIDVAKLNNQDEVL 229 LL+HG + + G T + A + N+D+++ Sbjct: 225 LLEHGTDPNIPDEYGNTTLHYA-IYNEDKLM 254 Score = 38.5 bits (88), Expect = 0.018 Identities = 26/99 (26%), Positives = 47/99 (47%) Frame = -1 Query: 516 LDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRK 337 L+ G D + D G LH+A + A+ LL GA +++ +K+ TPL ++ Sbjct: 226 LEHGTDPNIPDEYGNTTLHYAIYNEDKLMAKALLLYGADIESKNKHGLTPLLLGVHEQKQ 285 Query: 336 ECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 + V L+K A + + G+T + +A ++ LL Sbjct: 286 QVVKFLIKKKANLNALDRYGRTALILAVCCGSASIVSLL 324 Score = 35.4 bits (80), Expect = 0.15 Identities = 24/96 (25%), Positives = 46/96 (47%) Frame = -1 Query: 507 GADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECV 328 GAD + ++ G L + + + L++ A ++A+D+ T L A G V Sbjct: 262 GADIESKNKHGLTPLLLGVHEQKQQVVKFLIKKKANLNALDRYGRTALILAVCCGSASIV 321 Query: 327 DLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 LLL+ V+ Q++ G+T + A ++ + +LL Sbjct: 322 SLLLEQNIDVSSQDLSGQTAREYAVSSHHHVICQLL 357 Score = 33.5 bits (75), Expect = 0.59 Identities = 27/85 (31%), Positives = 40/85 (47%), Gaps = 2/85 (2%) Frame = -1 Query: 465 LHFACGYGEFKCAE-ILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQ 289 LH A +G+ + I++ V+ DK K T LH A+ G E V LLL + + Sbjct: 143 LHRAAWWGKVPRKDLIVMLRDTDVNKKDKQKRTALHLASANGNSEVVKLLLDRRCQLNVL 202 Query: 288 NMDGKTPIDVAKLNNQDE-VLKLLE 217 + +T + A +DE L LLE Sbjct: 203 DNKKRTALIKAVQCQEDECALMLLE 227
>V018_FOWPV (Q9J5I3) Putative ankyrin repeat protein FPV018| Length = 700 Score = 53.1 bits (126), Expect = 7e-07 Identities = 35/99 (35%), Positives = 49/99 (49%) Frame = -1 Query: 528 LKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAG 349 +K + GA+ +E D+ G L G+ E LL GA V+ D +KNT L YA Sbjct: 445 IKVLIKNGANVNERDNYGITPLMICSREGKVSNMEYLLANGADVNQTDYDKNTALTYAIR 504 Query: 348 YGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEV 232 KEC +LL+HGA + N TPI + K ++ V Sbjct: 505 NKSKECTRVLLEHGADMCFMNR-FHTPITIHKTHDNPAV 542 Score = 51.6 bits (122), Expect = 2e-06 Identities = 30/115 (26%), Positives = 54/115 (46%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMD 385 +H S+ + ++ GAD + + G+ +H AC Y + ++L++ GA V+ D Sbjct: 400 IHAAVSINTSRLTRLLINKGADVNVRNRYGKTPIHLACMYSKIGNIKVLIKNGANVNERD 459 Query: 384 KNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 TPL + G+ ++ LL +GA V + D T + A N E ++L Sbjct: 460 NYGITPLMICSREGKVSNMEYLLANGADVNQTDYDKNTALTYAIRNKSKECTRVL 514 Score = 33.9 bits (76), Expect = 0.45 Identities = 18/53 (33%), Positives = 29/53 (54%) Frame = -1 Query: 369 PLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLLEKD 211 P+H A LL+ GA V ++N GKTPI +A + ++ +K+L K+ Sbjct: 399 PIHAAVSINTSRLTRLLINKGADVNVRNRYGKTPIHLACMYSKIGNIKVLIKN 451
>RFXK_MOUSE (Q9Z205) DNA-binding protein RFXANK (Regulatory factor X subunit B)| (RFX-B) (Regulatory factor X-associated ankyrin-containing protein) (Ankyrin repeat-containing adapter protein Tvl-1) Length = 269 Score = 53.1 bits (126), Expect = 7e-07 Identities = 35/115 (30%), Positives = 55/115 (47%) Frame = -1 Query: 552 ASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKN 373 ++ G+ E ++ LD GAD E AL A G +LL+ ++ D N Sbjct: 141 SAFGEIETVRFLLDWGADPHILAKERESALSLASMGGYTDIVRLLLDRDVDINIYDWNGG 200 Query: 372 TPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLLEKDV 208 TPL YA +CV+ LL GA +T + G TP+D+A +V +++E + Sbjct: 201 TPLLYAVRGNHVKCVEALLARGADLTTEADSGYTPMDLAVALGYRKVQQVMESHI 255
>ASZ1_MOUSE (Q8VD46) Ankyrin repeat, SAM and basic leucine zipper| domain-containing protein 1 (Germ cell-specific ankyrin, SAM and basic leucine zipper domain-containing protein) Length = 475 Score = 52.8 bits (125), Expect = 9e-07 Identities = 30/80 (37%), Positives = 43/80 (53%) Frame = -1 Query: 459 FACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMD 280 +A G + +L+ GA V+A D+N T L +AA G K + LL+ GA LQ D Sbjct: 155 YAARDGHTQVVALLVAHGAEVNAQDENGYTALTWAARQGHKNVILKLLELGANKMLQTKD 214 Query: 279 GKTPIDVAKLNNQDEVLKLL 220 G+TP ++AK N E+ L Sbjct: 215 GRTPSEIAKRNKHLEIFNFL 234 Score = 52.8 bits (125), Expect = 9e-07 Identities = 42/120 (35%), Positives = 62/120 (51%), Gaps = 6/120 (5%) Frame = -1 Query: 558 HTASVGDGEGLKKALDGGADKDEEDSEGRRALHFAC---GYGE--FKCAEILLEAGAAVD 394 + ASV + E ++ LD GA+ D + L AC G E KC E+LL A + Sbjct: 85 YAASVANAELVRFLLDRGANASF-DKDKLTILISACSARGSEEQVLKCVELLLSRNADPN 143 Query: 393 AMDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPID-VAKLNNQDEVLKLLE 217 + TP+ YAA G + V LL+ HGA V Q+ +G T + A+ +++ +LKLLE Sbjct: 144 TACRRLMTPIMYAARDGHTQVVALLVAHGAEVNAQDENGYTALTWAARQGHKNVILKLLE 203 Score = 32.7 bits (73), Expect = 1.0 Identities = 28/99 (28%), Positives = 43/99 (43%) Frame = -1 Query: 507 GADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECV 328 GA+ + +D G AL +A G LLE GA K+ TP A E Sbjct: 172 GAEVNAQDENGYTALTWAARQGHKNVILKLLELGANKMLQTKDGRTPSEIAKRNKHLEIF 231 Query: 327 DLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLLEKD 211 + L ++TL ++GK + +L ++ + KLL D Sbjct: 232 NFL-----SLTLNPLEGK----LQQLTKEETICKLLATD 261 Score = 32.3 bits (72), Expect = 1.3 Identities = 23/77 (29%), Positives = 35/77 (45%), Gaps = 1/77 (1%) Frame = -1 Query: 444 GEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPI 265 G+ + LL++G VD+ + TPL YAA E V LL GA + I Sbjct: 57 GDISLVKELLDSGINVDSSFRYGWTPLMYAASVANAELVRFLLDRGANASFDKDKLTILI 116 Query: 264 DVAKL-NNQDEVLKLLE 217 ++++VLK +E Sbjct: 117 SACSARGSEEQVLKCVE 133
>CENG2_HUMAN (Q9UPQ3) Centaurin-gamma 2 (ARF-GAP with GTP-binding protein-like,| ankyrin repeat and pleckstrin homology domains 1) (AGAP-1) (GTP-binding and GTPase-activating protein 1) (GGAP1) Length = 857 Score = 52.8 bits (125), Expect = 9e-07 Identities = 33/95 (34%), Positives = 48/95 (50%), Gaps = 7/95 (7%) Frame = -1 Query: 570 SIVHHTASVGDGEGLKKAL----DGGADKDEE---DSEGRRALHFACGYGEFKCAEILLE 412 S+ H E L+ A+ G D+ E + +GR ALH AC G A++L+ Sbjct: 731 SLGQHLLRATADEDLRTAILLLAHGSRDEVNETCGEGDGRTALHLACRKGNVVLAQLLIW 790 Query: 411 AGAAVDAMDKNKNTPLHYAAGYGRKECVDLLLKHG 307 G V A D + NT L YA +EC+D+LL++G Sbjct: 791 YGVDVTARDAHGNTALAYARQASSQECIDVLLQYG 825
>ANR18_HUMAN (Q8IVF6) Ankyrin repeat domain-containing protein 18A| Length = 992 Score = 52.8 bits (125), Expect = 9e-07 Identities = 31/107 (28%), Positives = 49/107 (45%), Gaps = 1/107 (0%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGG-ADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAM 388 +H A GD +++ L D D D + R LH AC +G + +LL +D Sbjct: 38 IHRAAIKGDAAEVERCLTRRFRDLDARDRKDRTVLHLACAHGRVQVVTLLLHRRCQIDIC 97 Query: 387 DKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLN 247 D+ TPL A + C +LL+ GA ++++ G T + A N Sbjct: 98 DRLNRTPLMKAVHSQEEACAIVLLECGANPNIKDIYGNTALHYAVYN 144 Score = 49.3 bits (116), Expect = 1e-05 Identities = 32/99 (32%), Positives = 53/99 (53%) Frame = -1 Query: 516 LDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRK 337 L+ GA+ + +D G ALH+A AE LL A ++A++K NTPL +A R+ Sbjct: 121 LECGANPNIKDIYGNTALHYAVYNKGTSLAERLLSHHANIEALNKEGNTPLLFAINSRRQ 180 Query: 336 ECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 V+ LLK+ A + + +T + +A +N ++ LL Sbjct: 181 HMVEFLLKNQANIHAVDNFKRTALILAVQHNLSSIVTLL 219 Score = 38.9 bits (89), Expect = 0.014 Identities = 31/102 (30%), Positives = 45/102 (44%), Gaps = 1/102 (0%) Frame = -1 Query: 558 HTASVGDGEGL-KKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDK 382 H A G L ++ L A+ + + EG L FA E LL+ A + A+D Sbjct: 139 HYAVYNKGTSLAERLLSHHANIEALNKEGNTPLLFAINSRRQHMVEFLLKNQANIHAVDN 198 Query: 381 NKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVA 256 K T L A + V LLL+ ++ Q+M G+T D A Sbjct: 199 FKRTALILAVQHNLSSIVTLLLQQNIRISSQDMFGQTAEDYA 240
>AKR2_YEAST (Q12013) Probable palmitoyltransferase AKR2 (EC 2.3.1.-) (Ankyrin| repeat-containing protein AKR2) Length = 749 Score = 52.8 bits (125), Expect = 9e-07 Identities = 37/94 (39%), Positives = 50/94 (53%), Gaps = 2/94 (2%) Frame = -1 Query: 552 ASVGDGEGLKKALDGGA-DKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVD-AMDKN 379 A GD + +K ++ GA D + + + LH+AC F A+ LL GA + A Sbjct: 58 AKDGDLKVVKDVVESGAVDINNDRIDELSGLHWACINNRFSVAKFLLLRGANPNQAAGPG 117 Query: 378 KNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDG 277 T LH+AA YG VDLLLKHGA TL++ G Sbjct: 118 GATALHWAARYGNIYIVDLLLKHGADPTLKDEQG 151 Score = 39.7 bits (91), Expect = 0.008 Identities = 31/118 (26%), Positives = 48/118 (40%), Gaps = 6/118 (5%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILL------EAGA 403 +H A G+ + L GAD +D +G +HF+ +L Sbjct: 122 LHWAARYGNIYIVDLLLKHGADPTLKDEQGLNIMHFSVYSSNILLVVYVLYFVVNNNDNV 181 Query: 402 AVDAMDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVL 229 +D+ D N TPL +AA G V+LLLK G+ V + G + A + V+ Sbjct: 182 DIDSKDNNNRTPLLWAAYQGDFLTVELLLKFGSTVAWTDNRGFNALHCALVGGDQRVI 239
>V034_FOWPV (Q9J5G9) Putative ankyrin repeat protein FPV034| Length = 415 Score = 52.8 bits (125), Expect = 9e-07 Identities = 28/82 (34%), Positives = 45/82 (54%) Frame = -1 Query: 477 GRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLLKHGAAV 298 GR +LH A ++ A +L+ GA VD+ D NTP+ AA + LLL +GA + Sbjct: 238 GRTSLHLAIKERNYEAAFVLINNGANVDSFDDVGNTPIFIAASLQDVRFMKLLLDNGADI 297 Query: 297 TLQNMDGKTPIDVAKLNNQDEV 232 ++N+ G+TP+++ EV Sbjct: 298 NVRNVFGETPVNMVITGGSKEV 319 Score = 44.3 bits (103), Expect = 3e-04 Identities = 31/93 (33%), Positives = 48/93 (51%), Gaps = 1/93 (1%) Frame = -1 Query: 486 DSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLLKHG 307 DS G L +A + A+ILL+AG+ ++ KN LH A + K+ ++LL HG Sbjct: 74 DSVGYTLLRYAVEVDDVNIAKILLDAGSIIN---KNDYRLLHSAITHENKKMIELLCLHG 130 Query: 306 AAVTLQNMDGKTPIDVAKLNNQ-DEVLKLLEKD 211 + +++ G T + NN D V LLEK+ Sbjct: 131 ININVKDDKGYTALYYTICNNNYDMVCFLLEKN 163
>MIB2_CHICK (Q5ZIJ9) Ubiquitin ligase protein MIB2 (EC 6.3.2.-) (Mind bomb| homolog 2) Length = 954 Score = 52.8 bits (125), Expect = 9e-07 Identities = 39/121 (32%), Positives = 61/121 (50%), Gaps = 2/121 (1%) Frame = -1 Query: 570 SIVHHTASVGDGEGLKKALDGGADK-DEEDSEGRRALHFACGYGEFKCAEILLEAGAAVD 394 +++H++A G+ +KK L D + +G ALH A + AEIL++ G Sbjct: 600 NLLHYSALKGNKLAIKKILARARQLVDSKKEDGFTALHLAALNNHKEVAEILIKEGRCDV 659 Query: 393 AMDKNKN-TPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLLE 217 + N+N TPLH A G V LL+ G+ V ++ DG T + +A L Q + L+E Sbjct: 660 NVKNNRNQTPLHLAIIQGHVGLVQLLVSEGSDVNAEDEDGDTAMHIA-LERQQLMSVLME 718 Query: 216 K 214 K Sbjct: 719 K 719 Score = 51.6 bits (122), Expect = 2e-06 Identities = 34/111 (30%), Positives = 55/111 (49%) Frame = -1 Query: 552 ASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKN 373 A++ + +++ L DK + ++GR AL A G +ILL+A A V+ D+ + Sbjct: 440 AALNNAAKVRELLQKYPDKVDNKNQGRTALQIASYQGHLDVVKILLQAHATVNLRDEEGD 499 Query: 372 TPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 T LHYAA + + +L+ GA L N T + VA EV++ L Sbjct: 500 TALHYAAFGNQADVARVLMAKGAGADLLNNAKCTALYVAVSQGFTEVVQAL 550 Score = 35.8 bits (81), Expect = 0.12 Identities = 36/153 (23%), Positives = 59/153 (38%), Gaps = 35/153 (22%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMD 385 +H+ A + + + GA D ++ AL+ A G + + L E V+ D Sbjct: 502 LHYAAFGNQADVARVLMAKGAGADLLNNAKCTALYVAVSQGFTEVVQALCELNCDVNLPD 561 Query: 384 KNKNTPLHYAAGYGRKECVDLL-----------------LKHGAA--------------- 301 + +TPLHYA K +++L L H +A Sbjct: 562 SHGDTPLHYAITADYKVIIEILTEVPNIDFTVQNCQGFNLLHYSALKGNKLAIKKILARA 621 Query: 300 ---VTLQNMDGKTPIDVAKLNNQDEVLKLLEKD 211 V + DG T + +A LNN EV ++L K+ Sbjct: 622 RQLVDSKKEDGFTALHLAALNNHKEVAEILIKE 654
>ASB9_HUMAN (Q96DX5) Ankyrin repeat and SOCS box protein 9 (ASB-9)| Length = 294 Score = 52.8 bits (125), Expect = 9e-07 Identities = 38/117 (32%), Positives = 58/117 (49%) Frame = -1 Query: 570 SIVHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDA 391 S +H A G L+ + G + ++ LH AC G C +ILL+ GA V+ Sbjct: 38 SPMHEAAIHGHQLSLRNLISQGWAVNIITADHVSPLHEACLGGHLSCVKILLKHGAQVNG 97 Query: 390 MDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 + + +TPL A G +CV+LLL+HGA+V ++ D +PI A E + L Sbjct: 98 VTADWHTPLFNACVSGSWDCVNLLLQHGASVQPES-DLASPIHEAARRGHVECVNSL 153 Score = 50.8 bits (120), Expect = 4e-06 Identities = 32/104 (30%), Positives = 52/104 (50%) Frame = -1 Query: 570 SIVHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDA 391 S +H A G E + + G + D + S L+ AC + C + LLE+GA V+ Sbjct: 136 SPIHEAARRGHVECVNSLIAYGGNIDHKISHLGTPLYLACENQQRACVKKLLESGADVN- 194 Query: 390 MDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDV 259 K +++PLH A +E LL+ GA +N +GK P+++ Sbjct: 195 QGKGQDSPLHAVARTASEELACLLMDFGADTQAKNAEGKRPVEL 238 Score = 36.2 bits (82), Expect = 0.091 Identities = 24/91 (26%), Positives = 40/91 (43%) Frame = -1 Query: 492 EEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLLK 313 + +S+ +H A G +C L+ G +D + TPL+ A ++ CV LL+ Sbjct: 129 QPESDLASPIHEAARRGHVECVNSLIAYGGNIDHKISHLGTPLYLACENQQRACVKKLLE 188 Query: 312 HGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 GA V Q +P+ +E+ LL Sbjct: 189 SGADVN-QGKGQDSPLHAVARTASEELACLL 218
>ASB1_HUMAN (Q9Y576) Ankyrin repeat and SOCS box protein 1 (ASB-1)| Length = 335 Score = 52.4 bits (124), Expect = 1e-06 Identities = 28/89 (31%), Positives = 52/89 (58%) Frame = -1 Query: 552 ASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKN 373 A+ G G + + GA+ D D +G+ AL+ A G + +ILLEAGA + +++ Sbjct: 86 ATAGHGSCVDFLIRKGAEVDLVDVKGQTALYVAVVNGHLESTQILLEAGADPNGSRHHRS 145 Query: 372 TPLHYAAGYGRKECVDLLLKHGAAVTLQN 286 TP+++A+ GR + + L+++GA V + + Sbjct: 146 TPVYHASRVGRADILKALIRYGADVDVNH 174 Score = 40.0 bits (92), Expect = 0.006 Identities = 21/51 (41%), Positives = 30/51 (58%) Frame = -1 Query: 372 TPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 TPL AA G CVD L++ GA V L ++ G+T + VA +N E ++L Sbjct: 80 TPLRIAATAGHGSCVDFLIRKGAEVDLVDVKGQTALYVAVVNGHLESTQIL 130 Score = 40.0 bits (92), Expect = 0.006 Identities = 32/123 (26%), Positives = 49/123 (39%), Gaps = 8/123 (6%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGR--------RALHFACGYGEFKCAEILLEA 409 +H A VGD + L+ L + + + + L A G C + L+ Sbjct: 41 LHDAAYVGDLQTLRSLLQEESYRSRINEKSVWCCGWLPCTPLRIAATAGHGSCVDFLIRK 100 Query: 408 GAAVDAMDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVL 229 GA VD +D T L+ A G E +LL+ GA TP+ A + ++L Sbjct: 101 GAEVDLVDVKGQTALYVAVVNGHLESTQILLEAGADPNGSRHHRSTPVYHASRVGRADIL 160 Query: 228 KLL 220 K L Sbjct: 161 KAL 163 Score = 32.7 bits (73), Expect = 1.0 Identities = 32/103 (31%), Positives = 45/103 (43%), Gaps = 17/103 (16%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGAD--------KDEEDSEGRR-------ALHFACGYGEFKC 430 V+H + VG + LK + GAD D + RR L+ + Y +C Sbjct: 148 VYHASRVGRADILKALIRYGADVDVNHHLTPDVQPRFSRRLTSLVVCPLYISAAYHNLQC 207 Query: 429 AEILLEAGAAVDAMDKNKNTPLHYAAGY-GRKECV-DLLLKHG 307 +LL AGA D N N P++ Y G CV D +L+HG Sbjct: 208 FRLLLLAGANPDF---NCNGPVNTQGFYRGSPGCVMDAVLRHG 247
>ASB2_BOVIN (Q3SX45) Ankyrin repeat and SOCS box protein 2 (ASB-2)| Length = 633 Score = 52.4 bits (124), Expect = 1e-06 Identities = 36/111 (32%), Positives = 54/111 (48%) Frame = -1 Query: 552 ASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKN 373 A G E L+ GAD + + S+ AL+ AC G + E LL GA + +K+ Sbjct: 277 AQSGQLEALRFLAKYGADINTQASDSASALYEACKNGHEEVVEFLLSQGADANKTNKDGM 336 Query: 372 TPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 PLH A+ G V +LL + ++ G +P+ +A N DEVL+ L Sbjct: 337 LPLHIASKKGNYRIVQMLLPVTSRTRVRR-SGISPLHLAAERNNDEVLEAL 386 Score = 50.8 bits (120), Expect = 4e-06 Identities = 31/95 (32%), Positives = 48/95 (50%) Frame = -1 Query: 504 ADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVD 325 AD + + G ALH + + + EIL+ GA V+A + TPL AA G+ E + Sbjct: 227 ADTNHRCNRGWTALHESVARNDLEVMEILVSGGAKVEAKNAYGITPLFVAAQSGQLEALR 286 Query: 324 LLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 L K+GA + Q D + + A N +EV++ L Sbjct: 287 FLAKYGADINTQASDSASALYEACKNGHEEVVEFL 321 Score = 50.4 bits (119), Expect = 5e-06 Identities = 32/108 (29%), Positives = 49/108 (45%), Gaps = 1/108 (0%) Frame = -1 Query: 540 DGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEA-GAAVDAMDKNKNTPL 364 D E L + G + E + EG LH A YG+ C + L A A +D + T L Sbjct: 115 DEEALTAMIKAGKNLSEPNKEGWLPLHEAAYYGQLNCLKALHRAYPAVIDQRTLQEETAL 174 Query: 363 HYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 + A G +C+ LL+ GA + N +TP+ A E +++L Sbjct: 175 YLATCRGHVDCLQFLLQAGAEPDISNKSRETPLYKACERKNVEAVRIL 222 Score = 44.7 bits (104), Expect = 3e-04 Identities = 27/92 (29%), Positives = 46/92 (50%) Frame = -1 Query: 495 DEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLL 316 D+ + AL+ A G C + LL+AGA D +K++ TPL+ A E V +L+ Sbjct: 164 DQRTLQEETALYLATCRGHVDCLQFLLQAGAEPDISNKSRETPLYKACERKNVEAVRILV 223 Query: 315 KHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 ++ A + G T + + N EV+++L Sbjct: 224 QYKADTNHRCNRGWTALHESVARNDLEVMEIL 255 Score = 34.7 bits (78), Expect = 0.26 Identities = 22/85 (25%), Positives = 41/85 (48%) Frame = -1 Query: 570 SIVHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDA 391 S ++ G E ++ L GAD ++ + +G LH A G ++ ++LL + Sbjct: 304 SALYEACKNGHEEVVEFLLSQGADANKTNKDGMLPLHIASKKGNYRIVQMLLPVTSRT-R 362 Query: 390 MDKNKNTPLHYAAGYGRKECVDLLL 316 + ++ +PLH AA E ++ LL Sbjct: 363 VRRSGISPLHLAAERNNDEVLEALL 387
>NOTC1_BRARE (P46530) Neurogenic locus notch homolog protein 1 precursor| Length = 2437 Score = 52.4 bits (124), Expect = 1e-06 Identities = 31/97 (31%), Positives = 48/97 (49%) Frame = -1 Query: 504 ADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVD 325 AD + D G+ ALH+A A +LL+ GA D + + TPL AA G E Sbjct: 2007 ADPNAVDDSGKSALHWAAAVNNVDAAVVLLKNGANKDLQNNKEETPLFLAAREGSYETAK 2066 Query: 324 LLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLLEK 214 +LL H A + + + P D+A ++++LLE+ Sbjct: 2067 VLLDHLANRDIADHLDQLPRDIAHERMHHDIVRLLEE 2103 Score = 44.7 bits (104), Expect = 3e-04 Identities = 33/115 (28%), Positives = 51/115 (44%), Gaps = 2/115 (1%) Frame = -1 Query: 558 HTASVGDGEGLKKAL--DGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMD 385 H A D +G+ + L + D D +G L A E L+ A +A+D Sbjct: 1954 HAAVAADAQGVFQILIRNRATDLDARMHDGTTPLILATRLAVEGMVEELINCHADPNAVD 2013 Query: 384 KNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 + + LH+AA + +LLK+GA LQN +TP+ +A E K+L Sbjct: 2014 DSGKSALHWAAAVNNVDAAVVLLKNGANKDLQNNKEETPLFLAAREGSYETAKVL 2068 Score = 40.8 bits (94), Expect = 0.004 Identities = 25/81 (30%), Positives = 39/81 (48%), Gaps = 1/81 (1%) Frame = -1 Query: 495 DEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLL 316 ++ D G ALH A Y A+ LLE+ A + D TPLH A + +L+ Sbjct: 1910 NQTDRTGETALHLAARYARSDAAKRLLESCADANVQDNMGRTPLHAAVAADAQGVFQILI 1969 Query: 315 KHGAA-VTLQNMDGKTPIDVA 256 ++ A + + DG TP+ +A Sbjct: 1970 RNRATDLDARMHDGTTPLILA 1990 Score = 33.9 bits (76), Expect = 0.45 Identities = 18/56 (32%), Positives = 28/56 (50%) Frame = -1 Query: 387 DKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 D+ T LH AA Y R + LL+ A +Q+ G+TP+ A + V ++L Sbjct: 1913 DRTGETALHLAARYARSDAAKRLLESCADANVQDNMGRTPLHAAVAADAQGVFQIL 1968
>RFXK_HUMAN (O14593) DNA-binding protein RFXANK (Regulatory factor X subunit B)| (RFX-B) (Ankyrin repeat family A protein 1) Length = 260 Score = 52.4 bits (124), Expect = 1e-06 Identities = 35/115 (30%), Positives = 55/115 (47%) Frame = -1 Query: 552 ASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKN 373 ++ G+ E ++ L+ GAD E AL A G +LLE ++ D N Sbjct: 132 SAFGEIETVRFLLEWGADPHILAKERESALSLASTGGYTDIVGLLLERDVDINIYDWNGG 191 Query: 372 TPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLLEKDV 208 TPL YA +CV+ LL GA +T + G TP+D+A +V +++E + Sbjct: 192 TPLLYAVRGNHVKCVEALLARGADLTTEADSGYTPMDLAVALGYRKVQQVIENHI 246 Score = 46.6 bits (109), Expect = 7e-05 Identities = 32/116 (27%), Positives = 57/116 (49%), Gaps = 1/116 (0%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADK-DEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAM 388 +H A+ G+ + LK+ L G + ++ D G L +A +GE + LLE GA + Sbjct: 94 IHQLAAQGELDQLKEHLRKGDNLVNKPDERGFTPLIWASAFGEIETVRFLLEWGADPHIL 153 Query: 387 DKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 K + + L A+ G + V LLL+ + + + +G TP+ A N + ++ L Sbjct: 154 AKERESALSLASTGGYTDIVGLLLERDVDINIYDWNGGTPLLYAVRGNHVKCVEAL 209
>NOTC3_HUMAN (Q9UM47) Neurogenic locus notch homolog protein 3 precursor (Notch 3)| [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain] Length = 2321 Score = 52.4 bits (124), Expect = 1e-06 Identities = 32/97 (32%), Positives = 48/97 (49%) Frame = -1 Query: 504 ADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVD 325 AD + D G+ ALH+A + LL+ GA D D + TPL AA G E Sbjct: 1930 ADVNAVDELGKSALHWAAAVNNVEATLALLKNGANKDMQDSKEETPLFLAAREGSYEAAK 1989 Query: 324 LLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLLEK 214 LLL H A + + + P DVA+ ++++LL++ Sbjct: 1990 LLLDHFANREITDHLDRLPRDVAQERLHQDIVRLLDQ 2026 Score = 50.1 bits (118), Expect = 6e-06 Identities = 36/115 (31%), Positives = 55/115 (47%), Gaps = 2/115 (1%) Frame = -1 Query: 558 HTASVGDGEGLKKAL--DGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMD 385 HTA D +G+ + L + D D ++G AL A E L+ + A V+A+D Sbjct: 1877 HTAVTADAQGVFQILIRNRSTDLDARMADGSTALILAARLAVEGMVEELIASHADVNAVD 1936 Query: 384 KNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 + + LH+AA E LLK+GA +Q+ +TP+ +A E KLL Sbjct: 1937 ELGKSALHWAAAVNNVEATLALLKNGANKDMQDSKEETPLFLAAREGSYEAAKLL 1991 Score = 41.6 bits (96), Expect = 0.002 Identities = 25/78 (32%), Positives = 39/78 (50%), Gaps = 1/78 (1%) Frame = -1 Query: 486 DSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLLKHG 307 D G ALH A Y A+ LL+AGA +A D + TPLH A + +L+++ Sbjct: 1836 DRTGETALHLAARYARADAAKRLLDAGADTNAQDHSGRTPLHTAVTADAQGVFQILIRNR 1895 Query: 306 AA-VTLQNMDGKTPIDVA 256 + + + DG T + +A Sbjct: 1896 STDLDARMADGSTALILA 1913 Score = 36.6 bits (83), Expect = 0.070 Identities = 25/84 (29%), Positives = 39/84 (46%) Frame = -1 Query: 570 SIVHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDA 391 S +H A+V + E L GA+KD +DS+ L A G ++ A++LL+ A + Sbjct: 1941 SALHWAAAVNNVEATLALLKNGANKDMQDSKEETPLFLAAREGSYEAAKLLLDHFANREI 2000 Query: 390 MDKNKNTPLHYAAGYGRKECVDLL 319 D P A ++ V LL Sbjct: 2001 TDHLDRLPRDVAQERLHQDIVRLL 2024 Score = 36.6 bits (83), Expect = 0.070 Identities = 23/68 (33%), Positives = 33/68 (48%), Gaps = 1/68 (1%) Frame = -1 Query: 420 LLEAGAAVDAM-DKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNN 244 L+ GA + A D+ T LH AA Y R + LL GA Q+ G+TP+ A + Sbjct: 1824 LICQGAQLGARTDRTGETALHLAARYARADAAKRLLDAGADTNAQDHSGRTPLHTAVTAD 1883 Query: 243 QDEVLKLL 220 V ++L Sbjct: 1884 AQGVFQIL 1891
>POT15_HUMAN (Q6S5H4) Prostate, ovary, testis expressed protein on chromosome 15| Length = 581 Score = 52.4 bits (124), Expect = 1e-06 Identities = 29/91 (31%), Positives = 49/91 (53%) Frame = -1 Query: 501 DKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDL 322 D ++ D + R ALH A G + ++LL+ ++ +D K T L A ECV + Sbjct: 165 DMNKRDKQKRTALHLASANGNSEVVQLLLDRRCQLNVLDNKKRTALIKAVQCQEDECVLM 224 Query: 321 LLKHGAAVTLQNMDGKTPIDVAKLNNQDEVL 229 LL+HGA +Q+ G T + A + N+D+++ Sbjct: 225 LLEHGADGNIQDEYGNTALHYA-IYNEDKLM 254 Score = 51.2 bits (121), Expect = 3e-06 Identities = 37/117 (31%), Positives = 58/117 (49%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMD 385 +H ++ G+ E ++ LD + D++ R AL A E +C +LLE GA + D Sbjct: 177 LHLASANGNSEVVQLLLDRRCQLNVLDNKKRTALIKAVQCQEDECVLMLLEHGADGNIQD 236 Query: 384 KNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLLEK 214 + NT LHYA K LL +GA + +N G TP+ + + +V+K L K Sbjct: 237 EYGNTALHYAIYNEDKLMAKALLLYGADIESKNKCGLTPLLLGVHEQKQQVVKFLIK 293 Score = 40.8 bits (94), Expect = 0.004 Identities = 28/99 (28%), Positives = 49/99 (49%) Frame = -1 Query: 516 LDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRK 337 L+ GAD + +D G ALH+A + A+ LL GA +++ +K TPL ++ Sbjct: 226 LEHGADGNIQDEYGNTALHYAIYNEDKLMAKALLLYGADIESKNKCGLTPLLLGVHEQKQ 285 Query: 336 ECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 + V L+K A + + G+T + +A ++ LL Sbjct: 286 QVVKFLIKKKANLNALDRYGRTALILAVCCGSASIVNLL 324 Score = 34.7 bits (78), Expect = 0.26 Identities = 24/96 (25%), Positives = 47/96 (48%) Frame = -1 Query: 507 GADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECV 328 GAD + ++ G L + + + L++ A ++A+D+ T L A G V Sbjct: 262 GADIESKNKCGLTPLLLGVHEQKQQVVKFLIKKKANLNALDRYGRTALILAVCCGSASIV 321 Query: 327 DLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 +LLL+ V+ Q++ G+T + A ++ + +LL Sbjct: 322 NLLLEQNVDVSSQDLSGQTAREYAVSSHHHVICELL 357 Score = 34.3 bits (77), Expect = 0.35 Identities = 27/85 (31%), Positives = 41/85 (48%), Gaps = 2/85 (2%) Frame = -1 Query: 465 LHFACGYGEFKCAE-ILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQ 289 LH A +G+ + I++ ++ DK K T LH A+ G E V LLL + + Sbjct: 143 LHRAAWWGKVPRKDLIVMLRDTDMNKRDKQKRTALHLASANGNSEVVQLLLDRRCQLNVL 202 Query: 288 NMDGKTPIDVAKLNNQDE-VLKLLE 217 + +T + A +DE VL LLE Sbjct: 203 DNKKRTALIKAVQCQEDECVLMLLE 227
>NOTC3_RAT (Q9R172) Neurogenic locus notch homolog protein 3 precursor (Notch 3)| [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain] Length = 2319 Score = 52.4 bits (124), Expect = 1e-06 Identities = 32/97 (32%), Positives = 48/97 (49%) Frame = -1 Query: 504 ADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVD 325 AD + D G+ ALH+A + LL+ GA D D + TPL AA G E Sbjct: 1932 ADVNAVDELGKSALHWAAAVNNVEATLALLKNGANKDMQDSKEETPLFLAAREGSYEAAK 1991 Query: 324 LLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLLEK 214 LLL H A + + + P DVA+ ++++LL++ Sbjct: 1992 LLLDHFANREITDHLDRLPRDVAQERLHQDIVRLLDQ 2028 Score = 50.1 bits (118), Expect = 6e-06 Identities = 36/115 (31%), Positives = 55/115 (47%), Gaps = 2/115 (1%) Frame = -1 Query: 558 HTASVGDGEGLKKAL--DGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMD 385 HTA D +G+ + L + D D ++G AL A E L+ + A V+A+D Sbjct: 1879 HTAVTADAQGVFQILIRNRSTDLDARMADGSTALILAARLAVEGMVEELIASHADVNAVD 1938 Query: 384 KNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 + + LH+AA E LLK+GA +Q+ +TP+ +A E KLL Sbjct: 1939 ELGKSALHWAAAVNNVEATLALLKNGANKDMQDSKEETPLFLAAREGSYEAAKLL 1993 Score = 41.6 bits (96), Expect = 0.002 Identities = 25/78 (32%), Positives = 39/78 (50%), Gaps = 1/78 (1%) Frame = -1 Query: 486 DSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLLKHG 307 D G ALH A Y A+ LL+AGA +A D + TPLH A + +L+++ Sbjct: 1838 DRTGETALHLAARYARADAAKRLLDAGADTNAQDHSGRTPLHTAVTADAQGVFQILIRNR 1897 Query: 306 AA-VTLQNMDGKTPIDVA 256 + + + DG T + +A Sbjct: 1898 STDLDARMADGSTALILA 1915 Score = 36.6 bits (83), Expect = 0.070 Identities = 25/84 (29%), Positives = 39/84 (46%) Frame = -1 Query: 570 SIVHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDA 391 S +H A+V + E L GA+KD +DS+ L A G ++ A++LL+ A + Sbjct: 1943 SALHWAAAVNNVEATLALLKNGANKDMQDSKEETPLFLAAREGSYEAAKLLLDHFANREI 2002 Query: 390 MDKNKNTPLHYAAGYGRKECVDLL 319 D P A ++ V LL Sbjct: 2003 TDHLDRLPRDVAQERLHQDIVRLL 2026 Score = 36.6 bits (83), Expect = 0.070 Identities = 23/68 (33%), Positives = 33/68 (48%), Gaps = 1/68 (1%) Frame = -1 Query: 420 LLEAGAAVDAM-DKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNN 244 L+ GA + A D+ T LH AA Y R + LL GA Q+ G+TP+ A + Sbjct: 1826 LICQGAQLGARTDRTGETALHLAARYARADAAKRLLDAGADTNAQDHSGRTPLHTAVTAD 1885 Query: 243 QDEVLKLL 220 V ++L Sbjct: 1886 AQGVFQIL 1893
>ASB4_HUMAN (Q9Y574) Ankyrin repeat and SOCS box protein 4 (ASB-4)| Length = 426 Score = 52.4 bits (124), Expect = 1e-06 Identities = 34/105 (32%), Positives = 51/105 (48%), Gaps = 2/105 (1%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMD 385 +H + + + +K D GA + G ALHF CA+ L+ GA V+ Sbjct: 111 LHVACEMANVDCVKILCDRGAKLNCYSLSGHTALHFCTTPSSILCAKQLVWRGANVNMKT 170 Query: 384 KNKN--TPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVA 256 N++ TPLH AA +G E V ++HGA V N +TP+ +A Sbjct: 171 NNQDEETPLHTAAHFGLSELVAFYVEHGAIVDSVNAHMETPLAIA 215 Score = 42.4 bits (98), Expect = 0.001 Identities = 28/105 (26%), Positives = 48/105 (45%), Gaps = 2/105 (1%) Frame = -1 Query: 477 GRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLLKHGAAV 298 G+ LH AC C +IL + GA ++ + +T LH+ C L+ GA V Sbjct: 107 GKTPLHVACEMANVDCVKILCDRGAKLNCYSLSGHTALHFCTTPSSILCAKQLVWRGANV 166 Query: 297 TLQ--NMDGKTPIDVAKLNNQDEVLKLLEKDVFL*IASLGSHEET 169 ++ N D +TP+ A E++ + + + S+ +H ET Sbjct: 167 NMKTNNQDEETPLHTAAHFGLSELVAFYVEHGAI-VDSVNAHMET 210 Score = 40.8 bits (94), Expect = 0.004 Identities = 20/67 (29%), Positives = 33/67 (49%) Frame = -1 Query: 465 LHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQN 286 LH + +G +C +LL+ A ++ K TPLH A +CV +L GA + + Sbjct: 79 LHLSVLFGHVECLLVLLDHNATINCRPNGK-TPLHVACEMANVDCVKILCDRGAKLNCYS 137 Query: 285 MDGKTPI 265 + G T + Sbjct: 138 LSGHTAL 144 Score = 36.2 bits (82), Expect = 0.091 Identities = 28/77 (36%), Positives = 40/77 (51%), Gaps = 5/77 (6%) Frame = -1 Query: 372 TPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVA-KLNNQDEVLKLLEKDVFL*I 196 T LH + +G EC+ +LL H A + + +GKTP+ VA ++ N D V L ++ L Sbjct: 77 TGLHLSVLFGHVECLLVLLDHNATINCR-PNGKTPLHVACEMANVDCVKILCDRGAKLNC 135 Query: 195 ASLGSHEE----TWPSS 157 SL H T PSS Sbjct: 136 YSLSGHTALHFCTTPSS 152 Score = 33.1 bits (74), Expect = 0.77 Identities = 24/79 (30%), Positives = 33/79 (41%), Gaps = 7/79 (8%) Frame = -1 Query: 516 LDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRK 337 LD A+ + D + + LH A + ++LEAGA + MD N + Y Sbjct: 239 LDYKAEVNARDDDFKSPLHKAAWNCDHVLMHMMLEAGAEANLMDINGCAAIQYVLKVTSV 298 Query: 336 E-------CVDLLLKHGAA 301 C LLL HGAA Sbjct: 299 RPAAQPEICYQLLLNHGAA 317
>DDFL1_MOUSE (Q5U464) Development and differentiation enhancing factor-like 1| Length = 904 Score = 52.0 bits (123), Expect = 2e-06 Identities = 31/91 (34%), Positives = 48/91 (52%), Gaps = 3/91 (3%) Frame = -1 Query: 477 GRRALHFA---CGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLLKHG 307 G ALH A + + L++ G +DA + NT LH AA +G+ +C+ LLL+ Sbjct: 585 GELALHLAIRVASHASLPIVDFLIQNGGHLDAKAADGNTALHCAALHGQLDCLKLLLRGR 644 Query: 306 AAVTLQNMDGKTPIDVAKLNNQDEVLKLLEK 214 A V N G+T +D+A+ E +LLE+ Sbjct: 645 APVGAVNDAGETALDIARNRQHKECEELLEQ 675
>ASZ1_MICMU (Q2QL84) Ankyrin repeat, SAM and basic leucine zipper| domain-containing protein 1 (Germ cell-specific ankyrin, SAM and basic leucine zipper domain-containing protein) Length = 481 Score = 52.0 bits (123), Expect = 2e-06 Identities = 41/120 (34%), Positives = 63/120 (52%), Gaps = 6/120 (5%) Frame = -1 Query: 558 HTASVGDGEGLKKALDGGADKDEEDSEGRRALHFAC---GYGE--FKCAEILLEAGAAVD 394 + AS+ + E ++ LD GA+ D + + L AC G E KC E+LL A + Sbjct: 85 YAASIANVELVRVLLDRGANASF-DKDKQTILITACSARGSEEQILKCVELLLSRNADPN 143 Query: 393 AMDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPID-VAKLNNQDEVLKLLE 217 + TP+ YAA G + V +L+ HGA V Q+ +G T + A+ +++ VLKLLE Sbjct: 144 VACRRLMTPIMYAARDGHPQVVAVLVAHGAEVNTQDENGYTALTWAARQGHKNVVLKLLE 203 Score = 50.1 bits (118), Expect = 6e-06 Identities = 30/80 (37%), Positives = 41/80 (51%) Frame = -1 Query: 459 FACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMD 280 +A G + +L+ GA V+ D+N T L +AA G K V LL+ GA LQ D Sbjct: 155 YAARDGHPQVVAVLVAHGAEVNTQDENGYTALTWAARQGHKNVVLKLLELGANKMLQTKD 214 Query: 279 GKTPIDVAKLNNQDEVLKLL 220 GK P ++AK N E+ L Sbjct: 215 GKIPSEIAKRNKHLEIFNFL 234 Score = 35.0 bits (79), Expect = 0.20 Identities = 24/78 (30%), Positives = 42/78 (53%), Gaps = 2/78 (2%) Frame = -1 Query: 444 GEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPI 265 G+ + LL++G +VD+ + TPL YAA E V +LL GA + + D +T + Sbjct: 57 GDISLVQELLDSGISVDSSFRYGWTPLMYAASIANVELVRVLLDRGANASF-DKDKQTIL 115 Query: 264 DVA--KLNNQDEVLKLLE 217 A +++++LK +E Sbjct: 116 ITACSARGSEEQILKCVE 133
>USH1G_MOUSE (Q80T11) Usher syndrome type-1G protein homolog (Scaffold protein| containing ankyrin repeats and SAM domain) (Jackson shaker protein) Length = 461 Score = 52.0 bits (123), Expect = 2e-06 Identities = 34/115 (29%), Positives = 53/115 (46%) Frame = -1 Query: 561 HHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDK 382 H A G E LK+A + +ED G +A +G + +++ G D D Sbjct: 6 HRAARDGYLELLKEATRKELNAPDED--GMTPTLWAAYHGNLESLRLIVSRGGDPDKCDI 63 Query: 381 NKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLLE 217 NTPLH AA G C+ L+ GA + + D TP+D+A + E ++ L+ Sbjct: 64 WGNTPLHLAASNGHLHCLSFLVSFGANIWCLDNDYHTPLDMAAMKGHMECVRYLD 118
>USH1G_HUMAN (Q495M9) Usher syndrome type-1G protein (Scaffold protein| containing ankyrin repeats and SAM domain) Length = 461 Score = 52.0 bits (123), Expect = 2e-06 Identities = 34/115 (29%), Positives = 53/115 (46%) Frame = -1 Query: 561 HHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDK 382 H A G E LK+A + +ED G +A +G + +++ G D D Sbjct: 6 HRAARDGYLELLKEATRKELNAPDED--GMTPTLWAAYHGNLESLRLIVSRGGDPDKCDI 63 Query: 381 NKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLLE 217 NTPLH AA G C+ L+ GA + + D TP+D+A + E ++ L+ Sbjct: 64 WGNTPLHLAASNGHLHCLSFLVSFGANIWCLDNDYHTPLDMAAMKGHMECVRYLD 118
>NOTC3_MOUSE (Q61982) Neurogenic locus notch homolog protein 3 precursor (Notch 3)| [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain] Length = 2318 Score = 52.0 bits (123), Expect = 2e-06 Identities = 32/97 (32%), Positives = 48/97 (49%) Frame = -1 Query: 504 ADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVD 325 AD + D G+ ALH+A + LL+ GA D D + TPL AA G E Sbjct: 1931 ADVNAVDELGKSALHWAAAVNNVEATLALLKNGANKDMQDSKEETPLFLAAREGSYEAAK 1990 Query: 324 LLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLLEK 214 LLL H A + + + P DVA+ ++++LL++ Sbjct: 1991 LLLDHLANREITDHLDRLPRDVAQERLHQDIVRLLDQ 2027 Score = 50.1 bits (118), Expect = 6e-06 Identities = 36/115 (31%), Positives = 55/115 (47%), Gaps = 2/115 (1%) Frame = -1 Query: 558 HTASVGDGEGLKKAL--DGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMD 385 HTA D +G+ + L + D D ++G AL A E L+ + A V+A+D Sbjct: 1878 HTAVTADAQGVFQILIRNRSTDLDARMADGSTALILAARLAVEGMVEELIASHADVNAVD 1937 Query: 384 KNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 + + LH+AA E LLK+GA +Q+ +TP+ +A E KLL Sbjct: 1938 ELGKSALHWAAAVNNVEATLALLKNGANKDMQDSKEETPLFLAAREGSYEAAKLL 1992 Score = 41.6 bits (96), Expect = 0.002 Identities = 25/78 (32%), Positives = 39/78 (50%), Gaps = 1/78 (1%) Frame = -1 Query: 486 DSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLLKHG 307 D G ALH A Y A+ LL+AGA +A D + TPLH A + +L+++ Sbjct: 1837 DRTGETALHLAARYARADAAKRLLDAGADTNAQDHSGRTPLHTAVTADAQGVFQILIRNR 1896 Query: 306 AA-VTLQNMDGKTPIDVA 256 + + + DG T + +A Sbjct: 1897 STDLDARMADGSTALILA 1914 Score = 36.6 bits (83), Expect = 0.070 Identities = 23/68 (33%), Positives = 33/68 (48%), Gaps = 1/68 (1%) Frame = -1 Query: 420 LLEAGAAVDAM-DKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNN 244 L+ GA + A D+ T LH AA Y R + LL GA Q+ G+TP+ A + Sbjct: 1825 LICQGAQLGARTDRTGETALHLAARYARADAAKRLLDAGADTNAQDHSGRTPLHTAVTAD 1884 Query: 243 QDEVLKLL 220 V ++L Sbjct: 1885 AQGVFQIL 1892 Score = 36.2 bits (82), Expect = 0.091 Identities = 25/84 (29%), Positives = 39/84 (46%) Frame = -1 Query: 570 SIVHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDA 391 S +H A+V + E L GA+KD +DS+ L A G ++ A++LL+ A + Sbjct: 1942 SALHWAAAVNNVEATLALLKNGANKDMQDSKEETPLFLAAREGSYEAAKLLLDHLANREI 2001 Query: 390 MDKNKNTPLHYAAGYGRKECVDLL 319 D P A ++ V LL Sbjct: 2002 TDHLDRLPRDVAQERLHQDIVRLL 2025
>AKR1_CANGA (Q6FJ70) Palmitoyltransferase AKR1 (EC 2.3.1.-) (Ankyrin| repeat-containing protein AKR1) Length = 763 Score = 52.0 bits (123), Expect = 2e-06 Identities = 33/98 (33%), Positives = 49/98 (50%), Gaps = 3/98 (3%) Frame = -1 Query: 561 HHTASVGDGEGLKKALDGGADK--DEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAM 388 H+ GD E +++ + GG + D EG LH+A + L+ GA V++ Sbjct: 63 HNACQRGDLEVVREMIHGGQVNVSSDADREGVTGLHWAAINNRLNVVDFLVREGANVESK 122 Query: 387 -DKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDG 277 + TPLH+AA YG VD LL+HGA+ T + G Sbjct: 123 AGALEATPLHWAARYGFVYVVDYLLQHGASATTTDKQG 160 Score = 38.1 bits (87), Expect = 0.024 Identities = 25/86 (29%), Positives = 40/86 (46%) Frame = -1 Query: 510 GGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKEC 331 G D D D +GR AL +A G+ L++ A+V D+ TPLH+ G+ Sbjct: 187 GIIDIDYVDPKGRTALLWAAYQGDSLTVAALIKFNASVKIADEGGFTPLHWGTVKGQPHV 246 Query: 330 VDLLLKHGAAVTLQNMDGKTPIDVAK 253 + L++ GA + D K +A+ Sbjct: 247 LKYLIQDGADFFQKTNDNKDCFVIAE 272 Score = 37.0 bits (84), Expect = 0.053 Identities = 32/123 (26%), Positives = 48/123 (39%), Gaps = 5/123 (4%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILL-----EAGAA 400 +H A G + L GA D +G LH + +L + Sbjct: 131 LHWAARYGFVYVVDYLLQHGASATTTDKQGFNLLHLSVNSSNIMLVVYVLFFVVSKGIID 190 Query: 399 VDAMDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 +D +D T L +AA G V L+K A+V + + G TP+ + Q VLK L Sbjct: 191 IDYVDPKGRTALLWAAYQGDSLTVAALIKFNASVKIADEGGFTPLHWGTVKGQPHVLKYL 250 Query: 219 EKD 211 +D Sbjct: 251 IQD 253
>ASB4_MOUSE (Q9WV71) Ankyrin repeat and SOCS box protein 4 (ASB-4)| Length = 426 Score = 52.0 bits (123), Expect = 2e-06 Identities = 34/105 (32%), Positives = 51/105 (48%), Gaps = 2/105 (1%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMD 385 +H + + E +K D GA + G ALHF CA+ L+ GA V+ Sbjct: 111 LHVACEIANLECVKILCDRGAKLNCYSLSGHTALHFCTTPSSILCAKQLVLRGANVNMKT 170 Query: 384 KNKN--TPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVA 256 N++ TPLH AA +G E V +++GA V N +TP+ +A Sbjct: 171 NNQDEETPLHTAAHFGLSELVAFYVENGAIVDSMNAHMETPLAIA 215 Score = 46.2 bits (108), Expect = 9e-05 Identities = 35/134 (26%), Positives = 62/134 (46%), Gaps = 2/134 (1%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMD 385 +H + +G E L LD A + + G+ LH AC +C +IL + GA ++ Sbjct: 79 LHLSVLLGHVECLMVLLDHNATINCRPN-GKTPLHVACEIANLECVKILCDRGAKLNCYS 137 Query: 384 KNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQ--NMDGKTPIDVAKLNNQDEVLKLLEKD 211 + +T LH+ C L+ GA V ++ N D +TP+ A E++ ++ Sbjct: 138 LSGHTALHFCTTPSSILCAKQLVLRGANVNMKTNNQDEETPLHTAAHFGLSELVAFYVEN 197 Query: 210 VFL*IASLGSHEET 169 + + S+ +H ET Sbjct: 198 GAI-VDSMNAHMET 210 Score = 35.0 bits (79), Expect = 0.20 Identities = 24/79 (30%), Positives = 33/79 (41%), Gaps = 7/79 (8%) Frame = -1 Query: 516 LDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRK 337 LD A+ + D + + LH A + ++LEAGA + MD N + Y Sbjct: 239 LDNNAEVNARDDDFKSPLHKAAWNCDHVLMHMMLEAGAEANLMDINGCAAIQYVLKVTSV 298 Query: 336 E-------CVDLLLKHGAA 301 C LLL HGAA Sbjct: 299 RPAAQPEICYQLLLNHGAA 317 Score = 33.5 bits (75), Expect = 0.59 Identities = 27/77 (35%), Positives = 39/77 (50%), Gaps = 5/77 (6%) Frame = -1 Query: 372 TPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVA-KLNNQDEVLKLLEKDVFL*I 196 T LH + G EC+ +LL H A + + +GKTP+ VA ++ N + V L ++ L Sbjct: 77 TGLHLSVLLGHVECLMVLLDHNATINCR-PNGKTPLHVACEIANLECVKILCDRGAKLNC 135 Query: 195 ASLGSHEE----TWPSS 157 SL H T PSS Sbjct: 136 YSLSGHTALHFCTTPSS 152
>AKR1_NEUCR (Q7S3M5) Palmitoyltransferase AKR1 (EC 2.3.1.-) (Ankyrin| repeat-containing protein AKR1) Length = 729 Score = 51.6 bits (122), Expect = 2e-06 Identities = 34/102 (33%), Positives = 51/102 (50%), Gaps = 1/102 (0%) Frame = -1 Query: 516 LDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRK 337 L G D ED+ G AL ++ G C ++ L GA+V A D+ T LH+A G Sbjct: 164 LHQGIPVDVEDAYGHTALMWSAYKGFPACVDVFLRWGASVHAKDEQGFTALHWALVKGSP 223 Query: 336 ECVDLLLKHGAAVTLQNMDGKTP-IDVAKLNNQDEVLKLLEK 214 C+ L+++GA + +GKTP I +LN K L++ Sbjct: 224 GCIQKLIEYGADRFAKTANGKTPAITAQELNTVAAWQKALDE 265 Score = 47.0 bits (110), Expect = 5e-05 Identities = 33/113 (29%), Positives = 54/113 (47%), Gaps = 2/113 (1%) Frame = -1 Query: 552 ASVGDGEGLKKALDGGA-DKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMD-KN 379 A VGD G++K G D D EG LH+A ++ + L++ GA ++ ++ Sbjct: 51 ARVGDITGMEKLFAAGEYDATYSDDEGITPLHWAAINNQYAMCKFLIDKGAEINKKGGES 110 Query: 378 KNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 TPL +AA V LLL+HGA + + G + ++ N ++ LL Sbjct: 111 VATPLQWAAQRCHYYTVHLLLQHGADPLITDSQGYNTLHISTFNGNVLLIVLL 163 Score = 46.6 bits (109), Expect = 7e-05 Identities = 33/101 (32%), Positives = 48/101 (47%), Gaps = 1/101 (0%) Frame = -1 Query: 516 LDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRK 337 L GAD DS+G LH + G +LL G VD D +T L ++A G Sbjct: 131 LQHGADPLITDSQGYNTLHISTFNGNVLLIVLLLHQGIPVDVEDAYGHTALMWSAYKGFP 190 Query: 336 ECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDE-VLKLLE 217 CVD+ L+ GA+V ++ G T + A + + KL+E Sbjct: 191 ACVDVFLRWGASVHAKDEQGFTALHWALVKGSPGCIQKLIE 231
>AKR1_GIBZE (Q4I8B6) Palmitoyltransferase AKR1 (EC 2.3.1.-) (Ankyrin| repeat-containing protein AKR1) Length = 702 Score = 51.6 bits (122), Expect = 2e-06 Identities = 35/101 (34%), Positives = 50/101 (49%), Gaps = 1/101 (0%) Frame = -1 Query: 516 LDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRK 337 L GAD D++G LH + G +LL G VD +D +T L +AA G Sbjct: 116 LQHGADPLVTDAQGYNTLHISTFNGNVLLLVLLLHQGIPVDVIDTFGHTALMWAAYKGFP 175 Query: 336 ECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDE-VLKLLE 217 +CVDL L+ GA+V + G T + A + +LKL+E Sbjct: 176 QCVDLFLRWGASVHATDEQGFTALHWALVKGSPGCILKLIE 216 Score = 48.9 bits (115), Expect = 1e-05 Identities = 32/93 (34%), Positives = 46/93 (49%) Frame = -1 Query: 516 LDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRK 337 L G D D+ G AL +A G +C ++ L GA+V A D+ T LH+A G Sbjct: 149 LHQGIPVDVIDTFGHTALMWAAYKGFPQCVDLFLRWGASVHATDEQGFTALHWALVKGSP 208 Query: 336 ECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQD 238 C+ L+++GA + GKTP AK N + Sbjct: 209 GCILKLIEYGADRFAKTQTGKTPSVTAKELNTE 241 Score = 48.5 bits (114), Expect = 2e-05 Identities = 34/117 (29%), Positives = 56/117 (47%), Gaps = 2/117 (1%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGA-DKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAM 388 + A VGD ++K + G D D EG LH+A ++ + L+E GA ++ Sbjct: 32 IMQVARVGDVPAMEKLFESGEYDATYHDDEGITPLHWAAINNQYAMCKFLIEHGAEINRK 91 Query: 387 D-KNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 ++ TPL +AA V+LLL+HGA + + G + ++ N +L LL Sbjct: 92 GGESIATPLQWAAQRCHYYTVNLLLQHGADPLVTDAQGYNTLHISTFNGNVLLLVLL 148
>AKR2_SACBA (Q876L4) Probable palmitoyltransferase AKR2 (EC 2.3.1.-) (Ankyrin| repeat-containing protein AKR2) Length = 730 Score = 51.6 bits (122), Expect = 2e-06 Identities = 33/86 (38%), Positives = 48/86 (55%), Gaps = 2/86 (2%) Frame = -1 Query: 528 LKKALDGGA-DKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVD-AMDKNKNTPLHYA 355 +K+ ++ GA D +++ + LH+AC F A+ L+ GA V+ + T LH+A Sbjct: 49 VKEVVESGAIDINKDCIDELPGLHWACIKNRFSIAKFLIRRGANVNQTAGPERATALHWA 108 Query: 354 AGYGRKECVDLLLKHGAAVTLQNMDG 277 A YG VDLLLKHGA TL + G Sbjct: 109 ARYGHVYIVDLLLKHGANPTLIDGQG 134 Score = 38.1 bits (87), Expect = 0.024 Identities = 32/118 (27%), Positives = 46/118 (38%), Gaps = 6/118 (5%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILL------EAGA 403 +H A G + L GA+ D +G LHF+ +L Sbjct: 105 LHWAARYGHVYIVDLLLKHGANPTLIDGQGLNILHFSVYSSNIMLVVYVLYFVVSNNNNV 164 Query: 402 AVDAMDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVL 229 +D+ D N TPL +AA G V+LLLK GA V L + G + A + + Sbjct: 165 DIDSRDYNNRTPLLWAAYQGDFLTVELLLKFGATVALTDNRGFNALHCALVGGDQRAI 222
>V222_FOWPV (Q9J513) Putative ankyrin repeat protein FPV222| Length = 747 Score = 51.6 bits (122), Expect = 2e-06 Identities = 31/97 (31%), Positives = 50/97 (51%), Gaps = 1/97 (1%) Frame = -1 Query: 507 GADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECV 328 GA + + +GR LH AC Y + + L+E+G + +D TPL+YA Y R++ V Sbjct: 388 GASFNLTNRKGRTPLHTACKYNNTEAVKYLIESGCDTNIVDVMSFTPLNYAVYYEREDTV 447 Query: 327 DLLLKHGAA-VTLQNMDGKTPIDVAKLNNQDEVLKLL 220 +LL+ G L + +PI A N ++K+L Sbjct: 448 KILLESGCVDPNLCDYKEVSPIIQAIKRNNKNIIKML 484 Score = 51.2 bits (121), Expect = 3e-06 Identities = 38/114 (33%), Positives = 55/114 (48%), Gaps = 5/114 (4%) Frame = -1 Query: 543 GDGEGLKKALDGGADKDE-EDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTP 367 G E L+ L+ G + D E + A+H+A ++ IL+ A D D+ +NTP Sbjct: 306 GSKELLEILLEYGCNPDICEKTTSTYAMHYAVIRKHYEMLNILIRYDAYTDVKDRQQNTP 365 Query: 366 LHYAAGYGRKEC---VDLLLKHGAAVTLQNMDGKTPIDVA-KLNNQDEVLKLLE 217 HYA E + LL GA+ L N G+TP+ A K NN + V L+E Sbjct: 366 AHYAVKLPISESCKYLKLLKLAGASFNLTNRKGRTPLHTACKYNNTEAVKYLIE 419 Score = 47.0 bits (110), Expect = 5e-05 Identities = 31/105 (29%), Positives = 51/105 (48%), Gaps = 1/105 (0%) Frame = -1 Query: 525 KKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGY 346 K + GA + + + LH A G +K E+LL GA +A+ T LHY+ Sbjct: 121 KMLIQNGALVNMNNMKNITPLHIASSSGSYKMVELLLLHGANTNALTSYGETSLHYSVSS 180 Query: 345 GRKECVDLLLKHGAAVTLQNMDGKTPIDVA-KLNNQDEVLKLLEK 214 +LL+++G V + N D T + +A ++ + D V LL+K Sbjct: 181 NDLNISELLIENGTNVNVANKDSITALIIAVEIMSIDLVRLLLDK 225 Score = 41.2 bits (95), Expect = 0.003 Identities = 23/70 (32%), Positives = 38/70 (54%) Frame = -1 Query: 429 AEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKL 250 A++L++ GA V+ + TPLH A+ G + V+LLL HGA G+T + + Sbjct: 120 AKMLIQNGALVNMNNMKNITPLHIASSSGSYKMVELLLLHGANTNALTSYGETSLHYSVS 179 Query: 249 NNQDEVLKLL 220 +N + +LL Sbjct: 180 SNDLNISELL 189 Score = 39.7 bits (91), Expect = 0.008 Identities = 20/72 (27%), Positives = 38/72 (52%) Frame = -1 Query: 435 KCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVA 256 K ++L AGA+ + ++ TPLH A Y E V L++ G + ++ TP++ A Sbjct: 379 KYLKLLKLAGASFNLTNRKGRTPLHTACKYNNTEAVKYLIESGCDTNIVDVMSFTPLNYA 438 Query: 255 KLNNQDEVLKLL 220 +++ +K+L Sbjct: 439 VYYEREDTVKIL 450 Score = 30.0 bits (66), Expect = 6.5 Identities = 21/87 (24%), Positives = 37/87 (42%), Gaps = 1/87 (1%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAA-VDAM 388 +H + E +K ++ G D + D L++A Y +ILLE+G + Sbjct: 402 LHTACKYNNTEAVKYLIESGCDTNIVDVMSFTPLNYAVYYEREDTVKILLESGCVDPNLC 461 Query: 387 DKNKNTPLHYAAGYGRKECVDLLLKHG 307 D + +P+ A K + +LL G Sbjct: 462 DYKEVSPIIQAIKRNNKNIIKMLLNAG 488
>ASZ1_CARPS (Q2QLC6) Ankyrin repeat, SAM and basic leucine zipper| domain-containing protein 1 (Germ cell-specific ankyrin, SAM and basic leucine zipper domain-containing protein) Length = 475 Score = 51.2 bits (121), Expect = 3e-06 Identities = 38/119 (31%), Positives = 59/119 (49%), Gaps = 5/119 (4%) Frame = -1 Query: 558 HTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGE----FKCAEILLEAGAAVDA 391 + ASV + E ++ LD GA+ + + + + G KC E+LL A + Sbjct: 85 YAASVSNVELVRVLLDRGANANFDKDKQTILITTCSSRGSEEQIVKCVELLLSRNADPNV 144 Query: 390 MDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPID-VAKLNNQDEVLKLLE 217 + TP+ YAA G + V LL+ HGA V Q+ G T + A+ +++ VLKLLE Sbjct: 145 PCRRLMTPIMYAARDGHPQVVALLVAHGAEVNTQDESGYTALTWAARQGHKNVVLKLLE 203 Score = 44.3 bits (103), Expect = 3e-04 Identities = 28/80 (35%), Positives = 40/80 (50%) Frame = -1 Query: 459 FACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMD 280 +A G + +L+ GA V+ D++ T L +AA G K V LL+ GA LQ D Sbjct: 155 YAARDGHPQVVALLVAHGAEVNTQDESGYTALTWAARQGHKNVVLKLLELGADKMLQTKD 214 Query: 279 GKTPIDVAKLNNQDEVLKLL 220 G P ++AK E+ LL Sbjct: 215 GNIPSEIAKRYKHLEIFSLL 234 Score = 33.1 bits (74), Expect = 0.77 Identities = 24/81 (29%), Positives = 39/81 (48%) Frame = -1 Query: 546 VGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTP 367 +G + + L G +E++ ++AL G+ + LL +G +VD+ + TP Sbjct: 27 IGYLDRASQKLKGVLPTEEKNETFKKALTT----GDISLVQELLNSGISVDSSFRYGWTP 82 Query: 366 LHYAAGYGRKECVDLLLKHGA 304 L YAA E V +LL GA Sbjct: 83 LMYAASVSNVELVRVLLDRGA 103 Score = 32.7 bits (73), Expect = 1.0 Identities = 28/99 (28%), Positives = 42/99 (42%) Frame = -1 Query: 507 GADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECV 328 GA+ + +D G AL +A G LLE GA K+ N P A Y E Sbjct: 172 GAEVNTQDESGYTALTWAARQGHKNVVLKLLELGADKMLQTKDGNIPSEIAKRYKHLEIF 231 Query: 327 DLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLLEKD 211 LL +++L + GK + + ++ + KLL D Sbjct: 232 SLL-----SLSLNPLKGK----LQQQTKEETICKLLATD 261
>CENG2_MOUSE (Q8BXK8) Centaurin-gamma 2 (ARF-GAP with GTP-binding protein-like,| ankyrin repeat and pleckstrin homology domains 1) (AGAP-1) Length = 857 Score = 51.2 bits (121), Expect = 3e-06 Identities = 25/60 (41%), Positives = 36/60 (60%) Frame = -1 Query: 486 DSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLLKHG 307 + +GR ALH AC G A++L+ G V A D + NT L YA +EC+D+LL++G Sbjct: 766 EGDGRTALHLACRKGNVVLAQLLIWYGVDVMARDAHGNTALAYARQASSQECIDVLLQYG 825
>AKT1_ARATH (Q38998) Potassium channel AKT1| Length = 857 Score = 51.2 bits (121), Expect = 3e-06 Identities = 41/131 (31%), Positives = 60/131 (45%) Frame = -1 Query: 528 LKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAG 349 L + L G D +E D+ GR LH A G C +LLE A + D + PL A Sbjct: 534 LHQLLKRGLDPNESDNNGRTPLHIAASKGTLNCVLLLLEYHADPNCRDAEGSVPLWEAMV 593 Query: 348 YGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLLEKDVFL*IASLGSHEET 169 G ++ V +LL+HG+ + ++ G A+ N LKLL++ V L + T Sbjct: 594 EGHEKVVKVLLEHGSTIDAGDV-GHFACTAAEQGN----LKLLKEIV------LHGGDVT 642 Query: 168 WPSSCFTSLWH 136 P + TS H Sbjct: 643 RPRATGTSALH 653 Score = 40.4 bits (93), Expect = 0.005 Identities = 39/148 (26%), Positives = 57/148 (38%), Gaps = 31/148 (20%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMD 385 +H AS G + L+ AD + D+EG L A G K ++LLE G+ +DA D Sbjct: 555 LHIAASKGTLNCVLLLLEYHADPNCRDAEGSVPLWEAMVEGHEKVVKVLLEHGSTIDAGD 614 Query: 384 -------------------------------KNKNTPLHYAAGYGRKECVDLLLKHGAAV 298 + LH A E V LL+ GA V Sbjct: 615 VGHFACTAAEQGNLKLLKEIVLHGGDVTRPRATGTSALHTAVCEENIEMVKYLLEQGADV 674 Query: 297 TLQNMDGKTPIDVAKLNNQDEVLKLLEK 214 Q+M G TP D+A+ +++ L + Sbjct: 675 NKQDMHGWTPRDLAEQQGHEDIKALFRE 702
>ASB2_HUMAN (Q96Q27) Ankyrin repeat and SOCS box protein 2 (ASB-2)| Length = 587 Score = 51.2 bits (121), Expect = 3e-06 Identities = 31/107 (28%), Positives = 53/107 (49%) Frame = -1 Query: 540 DGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLH 361 + E +K + AD + + G ALH + + + +IL+ GA V++ + TPL Sbjct: 169 NAEAVKILVQHNADTNHRCNRGWTALHESVSRNDLEVMQILVSGGAKVESKNAYGITPLF 228 Query: 360 YAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 AA G+ E + L K+GA + Q D + + A N +EV++ L Sbjct: 229 VAAQSGQLEALRFLAKYGADINTQASDNASALYEACKNEHEEVVEFL 275 Score = 49.7 bits (117), Expect = 8e-06 Identities = 35/111 (31%), Positives = 53/111 (47%) Frame = -1 Query: 552 ASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKN 373 A G E L+ GAD + + S+ AL+ AC + E LL GA + +K+ Sbjct: 231 AQSGQLEALRFLAKYGADINTQASDNASALYEACKNEHEEVVEFLLSQGADANKTNKDGL 290 Query: 372 TPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 PLH A+ G V +LL + ++ G +P+ +A N DEVL+ L Sbjct: 291 LPLHIASKKGNYRIVQMLLPVTSRTRIRR-SGVSPLHLAAERNHDEVLEAL 340 Score = 46.6 bits (109), Expect = 7e-05 Identities = 37/142 (26%), Positives = 57/142 (40%), Gaps = 34/142 (23%) Frame = -1 Query: 543 GDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEIL------------------ 418 GD E LK + G + E + EG LH A YG+ C ++L Sbjct: 68 GDEEALKTMIKEGKNLAEPNKEGWLPLHEAAYYGQVGCLKVLQRAYPGTIDQRTLQEETA 127 Query: 417 ----------------LEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQN 286 L+AGA D +K++ TPL+ A E V +L++H A + Sbjct: 128 VYLATCRGHLDCLLSLLQAGAEPDISNKSRETPLYKACERKNAEAVKILVQHNADTNHRC 187 Query: 285 MDGKTPIDVAKLNNQDEVLKLL 220 G T + + N EV+++L Sbjct: 188 NRGWTALHESVSRNDLEVMQIL 209 Score = 32.0 bits (71), Expect = 1.7 Identities = 19/67 (28%), Positives = 34/67 (50%) Frame = -1 Query: 516 LDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRK 337 L GAD ++ + +G LH A G ++ ++LL + + ++ +PLH AA Sbjct: 276 LSQGADANKTNKDGLLPLHIASKKGNYRIVQMLLPVTSRT-RIRRSGVSPLHLAAERNHD 334 Query: 336 ECVDLLL 316 E ++ LL Sbjct: 335 EVLEALL 341
>PME5_CAEEL (Q9TXQ1) Poly(ADP-ribose) polymerase pme-5 (EC 2.4.2.30) (Poly| ADP-ribose metabolism enzyme 5) Length = 2276 Score = 51.2 bits (121), Expect = 3e-06 Identities = 32/82 (39%), Positives = 42/82 (51%) Frame = -1 Query: 465 LHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQN 286 L ACG G + A+ L+E GA V+ DK K TPL +A G+ LL GA++TL + Sbjct: 503 LMMACGKGYLEMAKKLVEKGALVEGKDKKKRTPLIHAMLNGQIHTAAFLLAKGASLTLAD 562 Query: 285 MDGKTPIDVAKLNNQDEVLKLL 220 G T A + LKLL Sbjct: 563 SSGNTAAHYAAAYGFLDCLKLL 584 Score = 46.6 bits (109), Expect = 7e-05 Identities = 27/72 (37%), Positives = 38/72 (52%) Frame = -1 Query: 534 EGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYA 355 E KK ++ GA + +D + R L A G+ A LL GA++ D + NT HYA Sbjct: 513 EMAKKLVEKGALVEGKDKKKRTPLIHAMLNGQIHTAAFLLAKGASLTLADSSGNTAAHYA 572 Query: 354 AGYGRKECVDLL 319 A YG +C+ LL Sbjct: 573 AAYGFLDCLKLL 584 Score = 39.7 bits (91), Expect = 0.008 Identities = 19/40 (47%), Positives = 23/40 (57%) Frame = -1 Query: 435 KCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLL 316 KC L++AGA VD D NTPLHYA G +L+L Sbjct: 711 KCFNTLIKAGAKVDVYDHEDNTPLHYALTNGNLMLFNLML 750 Score = 36.6 bits (83), Expect = 0.070 Identities = 29/96 (30%), Positives = 41/96 (42%), Gaps = 16/96 (16%) Frame = -1 Query: 495 DEEDSEGRRALHFACG-----------YGEFKCAEIL-----LEAGAAVDAMDKNKNTPL 364 D D R ALH+A G +GE ++ L ++ D N NT L Sbjct: 1117 DAVDKFNRTALHYAFGNENDFKEGNVPFGESDPIAVVSLLSSLIRPEQIEIADVNGNTIL 1176 Query: 363 HYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVA 256 H AA C+ L++ V L+N DG TP+ +A Sbjct: 1177 HLAAIKNSTICLMTLIRKKCHVDLKNKDGNTPLALA 1212 Score = 35.8 bits (81), Expect = 0.12 Identities = 25/81 (30%), Positives = 37/81 (45%), Gaps = 7/81 (8%) Frame = -1 Query: 570 SIVHHTASVGDGE--GLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEIL-----LE 412 S+ H+ A V + GL K ++ + E + +GR LH A + +L L Sbjct: 1052 SVWHYAARVNSHKTVGLFKMIESKGVRRETNDDGRSVLHVATLACDGSADSVLEPIAWLS 1111 Query: 411 AGAAVDAMDKNKNTPLHYAAG 349 +DA+DK T LHYA G Sbjct: 1112 TRCPIDAVDKFNRTALHYAFG 1132 Score = 34.7 bits (78), Expect = 0.26 Identities = 28/83 (33%), Positives = 38/83 (45%), Gaps = 4/83 (4%) Frame = -1 Query: 477 GRRALHFACGYGEFKCAEILL-EAGAAVD---AMDKNKNTPLHYAAGYGRKECVDLLLKH 310 G ALH A + LL E VD + +N+ TPL A G G E L++ Sbjct: 462 GNSALHLAVLRNNLDVVDALLAEPTIVVDNPTSTGQNRLTPLMMACGKGYLEMAKKLVEK 521 Query: 309 GAAVTLQNMDGKTPIDVAKLNNQ 241 GA V ++ +TP+ A LN Q Sbjct: 522 GALVEGKDKKKRTPLIHAMLNGQ 544 Score = 34.3 bits (77), Expect = 0.35 Identities = 21/64 (32%), Positives = 28/64 (43%) Frame = -1 Query: 486 DSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLLKHG 307 D G LH A C L+ VD +K+ NTPL A +GR+ L++ Sbjct: 1169 DVNGNTILHLAAIKNSTICLMTLIRKKCHVDLKNKDGNTPLALAVHHGRQSSALTLIQAN 1228 Query: 306 AAVT 295 A VT Sbjct: 1229 ADVT 1232 Score = 32.3 bits (72), Expect = 1.3 Identities = 25/101 (24%), Positives = 43/101 (42%) Frame = -1 Query: 558 HTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKN 379 H A++ D + K L K ++ LH A E + ++ D++ Sbjct: 319 HRATLKDQKLPAKILPVSVAKKAYMNKNITPLHTAAISNSTHMLEAMRAVYPTINIPDQD 378 Query: 378 KNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVA 256 +HYAA ++ LLK+G +VT+ +TP+ VA Sbjct: 379 NWYTMHYAACAPGTAPMEFLLKNGGSVTMLTKQTETPLHVA 419 Score = 32.0 bits (71), Expect = 1.7 Identities = 25/95 (26%), Positives = 39/95 (41%) Frame = -1 Query: 504 ADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVD 325 AD DS G+ LH F I+L+ D + T +Y K+C + Sbjct: 667 ADASLADSSGQTPLHL------FSMQRIILKGSGEAAENDAMRMTLDNY------KKCFN 714 Query: 324 LLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 L+K GA V + + + TP+ A N + L+ Sbjct: 715 TLIKAGAKVDVYDHEDNTPLHYALTNGNLMLFNLM 749
>BCL3_MOUSE (Q9Z2F6) B-cell lymphoma 3-encoded protein homolog (Protein Bcl-3)| Length = 440 Score = 51.2 bits (121), Expect = 3e-06 Identities = 34/92 (36%), Positives = 45/92 (48%), Gaps = 1/92 (1%) Frame = -1 Query: 528 LKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMD-KNKNTPLHYAA 352 L A G D + + EG ALH A G + +LLE GA +DA+D K+ +PL +A Sbjct: 212 LDSATSGSVDLEVRNYEGLTALHVAVNTGCQEAVLLLLERGADIDAVDIKSGRSPLIHAV 271 Query: 351 GYGRKECVDLLLKHGAAVTLQNMDGKTPIDVA 256 V LLL HGA V Q G + + A Sbjct: 272 ENNSLNMVQLLLLHGANVNAQMYSGSSALHSA 303 Score = 36.6 bits (83), Expect = 0.070 Identities = 28/104 (26%), Positives = 49/104 (47%), Gaps = 5/104 (4%) Frame = -1 Query: 510 GGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKEC 331 G + D ++ + LH A +L+ AGA+ A+D++ T +H A + C Sbjct: 148 GSREVDVHNNLRQTPLHLAVITTLPDMVRLLVTAGASPMALDRHGQTAIHLACEHRSPSC 207 Query: 330 VDLLLKHGAA----VTLQNMDGKTPIDVA-KLNNQDEVLKLLEK 214 + LL + + ++N +G T + VA Q+ VL LLE+ Sbjct: 208 LQALLDSATSGSVDLEVRNYEGLTALHVAVNTGCQEAVLLLLER 251
>VB04_VARV (P33823) Ankyrin repeat protein B4| Length = 558 Score = 50.8 bits (120), Expect = 4e-06 Identities = 38/126 (30%), Positives = 59/126 (46%), Gaps = 4/126 (3%) Frame = -1 Query: 567 IVHHTASVGDG--EGLKKALDGGADKDEEDSEGRRALHFACGYG--EFKCAEILLEAGAA 400 I H+ S + E +K L+ G+D D++D+ G C + + EI LE A Sbjct: 178 IYHYKKSESESYNELIKILLNNGSDVDKKDTHGNTPFILLCKHDIDNVELFEICLE-NAN 236 Query: 399 VDAMDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 +D++D N TPLHY + + + V L+ GA V +N G TP ++ + L Sbjct: 237 IDSVDFNGYTPLHYVSCRNKYDFVKSLISKGANVNTRNRFGTTPFYCGIIHGISLIKLYL 296 Query: 219 EKDVFL 202 E D L Sbjct: 297 ESDTEL 302
>V155_FOWPV (Q9J5A7) Putative ankyrin repeat protein FPV115| Length = 542 Score = 50.8 bits (120), Expect = 4e-06 Identities = 34/103 (33%), Positives = 57/103 (55%), Gaps = 4/103 (3%) Frame = -1 Query: 507 GADKDEEDSEGRRALHFACGYGEFKCAEILLEA---GAAVDAMDKNKNTPLHYAAGYGRK 337 G D + +D +G+ ALH+AC C E + E GA ++ D+ TPLH A YG Sbjct: 242 GLDINTKDKKGKTALHYACN--SINCIETVKEIMKYGADINVKDREGLTPLHSACKYGDL 299 Query: 336 ECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLK-LLEKD 211 + LL+++GA V ++ T +++A + E++K L+EK+ Sbjct: 300 KLSKLLIEYGADVKVKTT--STVLNLAVESGNVELVKFLIEKN 340 Score = 48.5 bits (114), Expect = 2e-05 Identities = 28/74 (37%), Positives = 42/74 (56%) Frame = -1 Query: 534 EGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYA 355 E +K+ + GAD + +D EG LH AC YG+ K +++L+E GA D K +T L+ A Sbjct: 267 ETVKEIMKYGADINVKDREGLTPLHSACKYGDLKLSKLLIEYGA--DVKVKTTSTVLNLA 324 Query: 354 AGYGRKECVDLLLK 313 G E V L++ Sbjct: 325 VESGNVELVKFLIE 338 Score = 40.0 bits (92), Expect = 0.006 Identities = 24/74 (32%), Positives = 39/74 (52%) Frame = -1 Query: 423 ILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNN 244 +LL+AG V++ K +TPLH G V LLL HGA + + G+TP++ A Sbjct: 365 LLLDAGMDVNS-SKCISTPLHLGVILGNSNIVKLLLDHGANINAIDKYGETPLEAANKRI 423 Query: 243 QDEVLKLLEKDVFL 202 + +L + + F+ Sbjct: 424 NIDYAELYKSNRFI 437 Score = 31.2 bits (69), Expect = 2.9 Identities = 18/45 (40%), Positives = 27/45 (60%) Frame = -1 Query: 426 EILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTL 292 ++LL GA ++ K+ PL++AA G E V+LLL +GA L Sbjct: 143 DLLLRYGALPNSR-KDGLLPLYHAAAAGNTEMVELLLSYGAKTNL 186
>ANRA2_HUMAN (Q9H9E1) Ankyrin repeat family A protein 2 (RFXANK-like 2)| Length = 313 Score = 50.8 bits (120), Expect = 4e-06 Identities = 32/100 (32%), Positives = 46/100 (46%) Frame = -1 Query: 516 LDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRK 337 L GAD AL AC G ++LL+ G V+ D N TPL YA Sbjct: 202 LQNGADPQLLGKGRESALSLACSKGYTDIVKMLLDCGVDVNEYDWNGGTPLLYAVHGNHV 261 Query: 336 ECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLLE 217 +CV +LL+ GA T++ G +D+A V +++E Sbjct: 262 KCVKMLLESGADPTIETDSGYNSMDLAVALGYRSVQQVIE 301 Score = 32.7 bits (73), Expect = 1.0 Identities = 23/70 (32%), Positives = 33/70 (47%), Gaps = 2/70 (2%) Frame = -1 Query: 549 SVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGA--AVDAMDKNK 376 S G + +K LD G D +E D G L +A KC ++LLE+GA ++ Sbjct: 224 SKGYTDIVKMLLDCGVDVNEYDWNGGTPLLYAVHGNHVKCVKMLLESGADPTIETDSGYN 283 Query: 375 NTPLHYAAGY 346 + L A GY Sbjct: 284 SMDLAVALGY 293
>OSTF1_MOUSE (Q62422) Osteoclast-stimulating factor 1 (SH3 domain protein 3)| Length = 215 Score = 50.8 bits (120), Expect = 4e-06 Identities = 33/104 (31%), Positives = 51/104 (49%), Gaps = 1/104 (0%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILL-EAGAAVDAM 388 +H A G+ L++ LD + D G AL++AC G E+L + ++ Sbjct: 77 LHEAAKRGNLSWLRECLDNRVGVNGLDKAGSTALYWACHGGHKDIVEVLFTQPNVELNQQ 136 Query: 387 DKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVA 256 +K +T LH AA G + V LLL GA L+N + K +D+A Sbjct: 137 NKLGDTALHAAAWKGYADIVQLLLAKGARTDLRNNEKKLALDMA 180
>ANRA2_MOUSE (Q99PE2) Ankyrin repeat family A protein 2 (RFXANK-like 2)| Length = 312 Score = 50.8 bits (120), Expect = 4e-06 Identities = 30/87 (34%), Positives = 42/87 (48%) Frame = -1 Query: 516 LDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRK 337 L GAD AL AC G ++LL+ G V+ D N TPL YA Sbjct: 201 LQNGADPQLLGKGRESALSLACSKGYTDIVKMLLDCGVDVNEYDWNGGTPLLYAVHGNHV 260 Query: 336 ECVDLLLKHGAAVTLQNMDGKTPIDVA 256 +CV +LL++GA T++ G +D+A Sbjct: 261 KCVKMLLENGADPTIETDSGYNSMDLA 287 Score = 31.6 bits (70), Expect = 2.2 Identities = 23/70 (32%), Positives = 32/70 (45%), Gaps = 2/70 (2%) Frame = -1 Query: 549 SVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGA--AVDAMDKNK 376 S G + +K LD G D +E D G L +A KC ++LLE GA ++ Sbjct: 223 SKGYTDIVKMLLDCGVDVNEYDWNGGTPLLYAVHGNHVKCVKMLLENGADPTIETDSGYN 282 Query: 375 NTPLHYAAGY 346 + L A GY Sbjct: 283 SMDLAVALGY 292
>ANR21_HUMAN (Q86YR6) Ankyrin repeat domain-containing protein 21 (Protein POTE)| (Prostate, ovary, testis expressed protein) Length = 584 Score = 50.8 bits (120), Expect = 4e-06 Identities = 29/91 (31%), Positives = 48/91 (52%) Frame = -1 Query: 501 DKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDL 322 D ++ D E R ALH A G + ++LL+ ++ +D K T L A ECV + Sbjct: 165 DMNKRDKEKRTALHLASANGNSEVVQLLLDRRCQLNVLDNKKRTALIKAIQCQEDECVLM 224 Query: 321 LLKHGAAVTLQNMDGKTPIDVAKLNNQDEVL 229 LL+HGA + + G T + A + N+D+++ Sbjct: 225 LLEHGADRNIPDEYGNTALHYA-IYNEDKLM 254 Score = 50.4 bits (119), Expect = 5e-06 Identities = 37/117 (31%), Positives = 58/117 (49%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMD 385 +H ++ G+ E ++ LD + D++ R AL A E +C +LLE GA + D Sbjct: 177 LHLASANGNSEVVQLLLDRRCQLNVLDNKKRTALIKAIQCQEDECVLMLLEHGADRNIPD 236 Query: 384 KNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLLEK 214 + NT LHYA K LL +GA + +N G TP+ + + +V+K L K Sbjct: 237 EYGNTALHYAIYNEDKLMAKALLLYGADIESKNKCGLTPLLLGVHEQKQQVVKFLIK 293 Score = 42.0 bits (97), Expect = 0.002 Identities = 28/99 (28%), Positives = 50/99 (50%) Frame = -1 Query: 516 LDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRK 337 L+ GAD++ D G ALH+A + A+ LL GA +++ +K TPL ++ Sbjct: 226 LEHGADRNIPDEYGNTALHYAIYNEDKLMAKALLLYGADIESKNKCGLTPLLLGVHEQKQ 285 Query: 336 ECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 + V L+K A + + + G+T + +A ++ LL Sbjct: 286 QVVKFLIKKKANLNVLDRYGRTALILAVCCGSASIVNLL 324 Score = 33.9 bits (76), Expect = 0.45 Identities = 27/85 (31%), Positives = 41/85 (48%), Gaps = 2/85 (2%) Frame = -1 Query: 465 LHFACGYGEFKCAE-ILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQ 289 LH A +G+ + I++ ++ DK K T LH A+ G E V LLL + + Sbjct: 143 LHRAAWWGKVPRKDLIVMLRDTDMNKRDKEKRTALHLASANGNSEVVQLLLDRRCQLNVL 202 Query: 288 NMDGKTPIDVAKLNNQDE-VLKLLE 217 + +T + A +DE VL LLE Sbjct: 203 DNKKRTALIKAIQCQEDECVLMLLE 227
>POTE8_HUMAN (Q6S8J7) Prostate, ovary, testis expressed protein on chromosome 8| Length = 498 Score = 50.8 bits (120), Expect = 4e-06 Identities = 30/96 (31%), Positives = 42/96 (43%) Frame = -1 Query: 507 GADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECV 328 G ++ D + R ALH AC G + +LL+ + D K T L A EC Sbjct: 89 GPGINKRDKKKRTALHLACANGNSEVVSLLLDRQCQLHVFDSKKRTALIKAVQCQEDECA 148 Query: 327 DLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 +LL+HG L +M G T + A N + K L Sbjct: 149 LMLLQHGTDPNLPDMYGNTALHYAVYNEDKLMAKTL 184 Score = 49.3 bits (116), Expect = 1e-05 Identities = 37/117 (31%), Positives = 54/117 (46%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMD 385 +H + G+ E + LD DS+ R AL A E +CA +LL+ G + D Sbjct: 103 LHLACANGNSEVVSLLLDRQCQLHVFDSKKRTALIKAVQCQEDECALMLLQHGTDPNLPD 162 Query: 384 KNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLLEK 214 NT LHYA K LL +GA + +N G TP+ +A + ++K L K Sbjct: 163 MYGNTALHYAVYNEDKLMAKTLLLYGADIESKNKGGLTPLLLAVHGQKQRMVKFLIK 219 Score = 39.3 bits (90), Expect = 0.011 Identities = 32/108 (29%), Positives = 47/108 (43%), Gaps = 12/108 (11%) Frame = -1 Query: 507 GADKDEEDS-----------EGRRALHFACGYGEFKCAE-ILLEAGAAVDAMDKNKNTPL 364 GA +D +DS E LH A +GE A+ I++ G ++ DK K T L Sbjct: 44 GAWRDHDDSAFTEPRYHVRREDLGKLHRAAWWGEVPRADLIVMLRGPGINKRDKKKRTAL 103 Query: 363 HYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 H A G E V LLL + + + +T + A +DE +L Sbjct: 104 HLACANGNSEVVSLLLDRQCQLHVFDSKKRTALIKAVQCQEDECALML 151 Score = 38.5 bits (88), Expect = 0.018 Identities = 28/99 (28%), Positives = 46/99 (46%) Frame = -1 Query: 516 LDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRK 337 L G D + D G ALH+A + A+ LL GA +++ +K TPL A ++ Sbjct: 152 LQHGTDPNLPDMYGNTALHYAVYNEDKLMAKTLLLYGADIESKNKGGLTPLLLAVHGQKQ 211 Query: 336 ECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 V L+K A + + G+T + +A ++ LL Sbjct: 212 RMVKFLIKKKANLNALDRFGRTALILAVRCGSASIVSLL 250 Score = 35.4 bits (80), Expect = 0.15 Identities = 30/115 (26%), Positives = 52/115 (45%) Frame = -1 Query: 564 VHHTASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMD 385 +H+ D K L GAD + ++ G L A + + + L++ A ++A+D Sbjct: 169 LHYAVYNEDKLMAKTLLLYGADIESKNKGGLTPLLLAVHGQKQRMVKFLIKKKANLNALD 228 Query: 384 KNKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 + T L A G V LLL+ V Q++ G+T D A ++ + +LL Sbjct: 229 RFGRTALILAVRCGSASIVSLLLQQNIDVFSQDVFGQTAEDYAVSSHHSIICQLL 283
>Y3287_PSEAE (Q9HYV6) Hypothetical ANK-repeat protein PA3287| Length = 171 Score = 50.4 bits (119), Expect = 5e-06 Identities = 33/110 (30%), Positives = 51/110 (46%) Frame = -1 Query: 543 GDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPL 364 G + ++ L AD D + G+ L A G+ E+LL GA V+ + T L Sbjct: 60 GHADTVRLLLAYKADPDLRNLAGQTPLAGAAFKGDLAMVELLLAGGADVEGASADGKTAL 119 Query: 363 HYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLLEK 214 AA + + E LL HGA Q+ G TP+ A++ N + + LL + Sbjct: 120 MMAAMFNQAEVAASLLAHGARRDAQDAAGLTPLAAARMMNAEATVALLSR 169 Score = 45.1 bits (105), Expect = 2e-04 Identities = 35/107 (32%), Positives = 50/107 (46%) Frame = -1 Query: 552 ASVGDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKN 373 A G+ + L++ L G + + +G L A +G +LL A D + Sbjct: 24 ARQGNSQRLEQLLQQGLPPNLRNHKGDSLLMLASYHGHADTVRLLLAYKADPDLRNLAGQ 83 Query: 372 TPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEV 232 TPL AA G V+LLL GA V + DGKT + +A + NQ EV Sbjct: 84 TPLAGAAFKGDLAMVELLLAGGADVEGASADGKTALMMAAMFNQAEV 130 Score = 32.0 bits (71), Expect = 1.7 Identities = 25/92 (27%), Positives = 42/92 (45%) Frame = -1 Query: 495 DEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLL 316 D E E L G + E LL+ G + + ++ L A+ +G + V LLL Sbjct: 10 DMETQEFVHQLFDLARQGNSQRLEQLLQQGLPPNLRNHKGDSLLMLASYHGHADTVRLLL 69 Query: 315 KHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 + A L+N+ G+TP+ A +++LL Sbjct: 70 AYKADPDLRNLAGQTPLAGAAFKGDLAMVELL 101
>SAMD6_HUMAN (Q68DC2) Sterile alpha motif domain-containing protein 6 (Ankyrin| repeat domain-containing protein 14) Length = 871 Score = 50.4 bits (119), Expect = 5e-06 Identities = 36/108 (33%), Positives = 46/108 (42%) Frame = -1 Query: 543 GDGEGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKNTPL 364 G G A+ D D G AL FA G LL GA+V++ + + L Sbjct: 56 GPGAAAAGAVGAPVPVDCSDEAGNTALQFAAAGGHEPLVRFLLRRGASVNSRNHYGWSAL 115 Query: 363 HYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNNQDEVLKLL 220 AA +G LLL HGA V QN G + + VA V+KLL Sbjct: 116 MQAARFGHVSVAHLLLDHGADVNAQNRLGASVLTVASRGGHLGVVKLL 163 Score = 31.6 bits (70), Expect = 2.2 Identities = 26/85 (30%), Positives = 39/85 (45%), Gaps = 14/85 (16%) Frame = -1 Query: 516 LDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVD---------AMDKNKNTPL 364 LD GAD + ++ G L A G ++LLEAGA VD + +++ PL Sbjct: 131 LDHGADVNAQNRLGASVLTVASRGGHLGVVKLLLEAGAFVDHHHPSGEQLGLGGSRDEPL 190 Query: 363 HYAA-----GYGRKECVDLLLKHGA 304 A +G + V LL++ GA Sbjct: 191 DITALMAAIQHGHEAVVRLLMEWGA 215
>ZDH13_MOUSE (Q9CWU2) Probable palmitoyltransferase ZDHHC13 (EC 2.3.1.-) (Zinc| finger DHHC domain-containing protein 13) (DHHC-13) (Huntingtin-interacting protein 14-related protein) (HIP14-related protein) Length = 622 Score = 50.4 bits (119), Expect = 5e-06 Identities = 32/96 (33%), Positives = 49/96 (51%), Gaps = 1/96 (1%) Frame = -1 Query: 534 EGLKKALDGGADKDEEDSEGRRALHFACGYGEFKCAEILLEAGAAVDAMDKNKN-TPLHY 358 E K+ ++ G D + D E LH+A + + + GA +D + + N TPLH+ Sbjct: 63 ERCKELVEAGYDVRQPDRENVSLLHWAAINNRLELVKFYISKGAVIDQLGGDLNSTPLHW 122 Query: 357 AAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKL 250 A G V LLL+HGA TL + +G + I +A L Sbjct: 123 AIRQGHLPMVILLLQHGADPTLIDGEGFSSIHLAVL 158 Score = 48.1 bits (113), Expect = 2e-05 Identities = 28/98 (28%), Positives = 53/98 (54%), Gaps = 1/98 (1%) Frame = -1 Query: 420 LLEAGAAVDAMDK-NKNTPLHYAAGYGRKECVDLLLKHGAAVTLQNMDGKTPIDVAKLNN 244 LL+ ++ +DK ++NTPLH+A G VD LL+ G+++ ++N G+TP+D+A + Sbjct: 202 LLKFNPSLSVVDKTHQNTPLHWAVAAGNVSAVDKLLEAGSSLDIRNAKGETPLDMALQSK 261 Query: 243 QDEVLKLLEKDVFL*IASLGSHEETWPSSCFTSLWHWL 130 + +L + A + ++++ LW WL Sbjct: 262 NQLISHMLRTE-----AKMRANKQ-------FRLWRWL 287 Score = 31.6 bits (70), Expect = 2.2 Identities = 19/53 (35%), Positives = 27/53 (50%) Frame = -1 Query: 456 ACGYGEFKCAEILLEAGAAVDAMDKNKNTPLHYAAGYGRKECVDLLLKHGAAV 298 A YG F+ + L+EAG V D+ + LH+AA R E V + GA + Sbjct: 56 ATQYGIFERCKELVEAGYDVRQPDRENVSLLHWAAINNRLELVKFYISKGAVI 108 Database: uniprot_sprot.fasta Posted date: May 25, 2006 5:36 PM Number of letters in database: 80,573,946 Number of sequences in database: 219,361 Lambda K H 0.318 0.135 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 89,372,535 Number of Sequences: 219361 Number of extensions: 1717443 Number of successful extensions: 6718 Number of sequences better than 10.0: 469 Number of HSP's better than 10.0 without gapping: 4886 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 6316 length of database: 80,573,946 effective HSP length: 108 effective length of database: 56,882,958 effective search space used: 6427774254 frameshift window, decay const: 50, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
