ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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| Clone Name | rbasd13c18 |
|---|---|
| Clone Library Name | barley_pub |
>HETE1_PODAN (Q00808) Vegetatible incompatibility protein HET-E-1| Length = 1356 Score = 88.6 bits (218), Expect = 2e-17 Identities = 50/124 (40%), Positives = 70/124 (56%), Gaps = 1/124 (0%) Frame = -2 Query: 638 SGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCE-HDEGVTCL 462 SG +L GH +S+ + S VA+GSID T+ IWD A T E H V + Sbjct: 1082 SGTCTQTLEGHGDSVWSVAFSPDGQRVASGSIDGTIKIWDAASGTCTQTLEGHGGWVHSV 1141 Query: 461 AWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSA 282 A+ + VASG IDG ++IWD+ SG +T GH VQS+A S DG + S S+DK+ Sbjct: 1142 AFSPDGQRVASGSIDGTIKIWDAASGTCTQTLEGHGGWVQSVAFSPDGQRVASGSSDKTI 1201 Query: 281 RVFD 270 +++D Sbjct: 1202 KIWD 1205 Score = 80.1 bits (196), Expect = 5e-15 Identities = 47/132 (35%), Positives = 68/132 (51%), Gaps = 1/132 (0%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCE- 486 ++ I SG +L GH + + S VA+GSID T+ IWD A T E Sbjct: 1116 TIKIWDAASGTCTQTLEGHGGWVHSVAFSPDGQRVASGSIDGTIKIWDAASGTCTQTLEG 1175 Query: 485 HDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIV 306 H V +A+ + VASG D ++IWD+ SG +T GH VQS+A S DG + Sbjct: 1176 HGGWVQSVAFSPDGQRVASGSSDKTIKIWDTASGTCTQTLEGHGGWVQSVAFSPDGQRVA 1235 Query: 305 SVSTDKSARVFD 270 S S+D + +++D Sbjct: 1236 SGSSDNTIKIWD 1247 Score = 79.3 bits (194), Expect = 9e-15 Identities = 46/132 (34%), Positives = 67/132 (50%), Gaps = 1/132 (0%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCE- 486 ++ I SG +L GH ++ + S VA+GS D T+ IWD A T E Sbjct: 906 TIKIWDAASGTCTQTLEGHGGRVQSVAFSPDGQRVASGSDDHTIKIWDAASGTCTQTLEG 965 Query: 485 HDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIV 306 H V +A+ + VASG D ++IWD+ SG +T GH V S+A S DG + Sbjct: 966 HGSSVLSVAFSPDGQRVASGSGDKTIKIWDTASGTCTQTLEGHGGSVWSVAFSPDGQRVA 1025 Query: 305 SVSTDKSARVFD 270 S S DK+ +++D Sbjct: 1026 SGSDDKTIKIWD 1037 Score = 78.2 bits (191), Expect = 2e-14 Identities = 46/132 (34%), Positives = 68/132 (51%), Gaps = 1/132 (0%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCE- 486 ++ I SG +L GH S+ + S VA+GS D+T+ IWD A T E Sbjct: 990 TIKIWDTASGTCTQTLEGHGGSVWSVAFSPDGQRVASGSDDKTIKIWDTASGTCTQTLEG 1049 Query: 485 HDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIV 306 H V + + + VASG D ++IWD++SG +T GH D V S+A S DG + Sbjct: 1050 HGGWVQSVVFSPDGQRVASGSDDHTIKIWDAVSGTCTQTLEGHGDSVWSVAFSPDGQRVA 1109 Query: 305 SVSTDKSARVFD 270 S S D + +++D Sbjct: 1110 SGSIDGTIKIWD 1121 Score = 76.6 bits (187), Expect = 6e-14 Identities = 45/132 (34%), Positives = 68/132 (51%), Gaps = 1/132 (0%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCE- 486 ++ +V +L GH +S+ + S+ VA+GS D+T+ IWD A T E Sbjct: 822 TISVVEAEWNACTQTLEGHGSSVLSVAFSADGQRVASGSDDKTIKIWDTASGTGTQTLEG 881 Query: 485 HDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIV 306 H V +A+ VASG D ++IWD+ SG +T GH VQS+A S DG + Sbjct: 882 HGGSVWSVAFSPDRERVASGSDDKTIKIWDAASGTCTQTLEGHGGRVQSVAFSPDGQRVA 941 Query: 305 SVSTDKSARVFD 270 S S D + +++D Sbjct: 942 SGSDDHTIKIWD 953 Score = 55.8 bits (133), Expect = 1e-07 Identities = 33/101 (32%), Positives = 50/101 (49%), Gaps = 1/101 (0%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCE- 486 ++ I SG +L GH ++ + S VA+GS D+T+ IWD A T E Sbjct: 1158 TIKIWDAASGTCTQTLEGHGGWVQSVAFSPDGQRVASGSSDKTIKIWDTASGTCTQTLEG 1217 Query: 485 HDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFS 363 H V +A+ + VASG D ++IWD+ SG +T + Sbjct: 1218 HGGWVQSVAFSPDGQRVASGSSDNTIKIWDTASGTCTQTLN 1258 Score = 38.9 bits (89), Expect = 0.014 Identities = 22/76 (28%), Positives = 35/76 (46%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCEH 483 ++ I SG +L GH ++ + S VA+GS D T+ IWD A T Sbjct: 1200 TIKIWDTASGTCTQTLEGHGGWVQSVAFSPDGQRVASGSSDNTIKIWDTASGTCTQTLNV 1259 Query: 482 DEGVTCLAWLGSSRYV 435 TCL++ ++ Y+ Sbjct: 1260 GSTATCLSFDYTNAYI 1275
>AAMP_PONPY (Q5RCG7) Angio-associated migratory cell protein| Length = 434 Score = 86.3 bits (212), Expect = 8e-17 Identities = 48/142 (33%), Positives = 72/142 (50%), Gaps = 15/142 (10%) Frame = -2 Query: 653 IVSINSGQVVGSLVGHT---------------NSIECIGISSRYNWVATGSIDRTLIIWD 519 +VS +G+VVG T NS+E +G S A G +D TL I+D Sbjct: 286 LVSATTGKVVGVFRPETVASQPSLGEGEESESNSVESLGFCSVMPLAAVGYLDGTLAIYD 345 Query: 518 LARQAIRSTCEHDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQS 339 LA Q +R C+H G+ L W + V + +DG+VR+WD+ +G L + GH + Sbjct: 346 LATQTLRHQCQHQSGIVQLLWEAGTAVVYTCSLDGIVRLWDARTGRLLTDYRGHTAEILD 405 Query: 338 LAVSADGNSIVSVSTDKSARVF 273 A+S D + +V+ S D A+VF Sbjct: 406 FALSKDASLVVTTSGDHKAKVF 427 Score = 45.4 bits (106), Expect = 1e-04 Identities = 32/127 (25%), Positives = 57/127 (44%), Gaps = 1/127 (0%) Frame = -2 Query: 644 INSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDL-ARQAIRSTCEHDEGVT 468 ++ G+++ GH +S+ C G S VATG + L +W + ++ + S D + Sbjct: 121 LSDGELLFECAGHKDSVTCAGFSHDSTLVATGDMSGLLKVWQVDTKEEVWSFEAGD--LE 178 Query: 467 CLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDK 288 + W + + +G DG +W +GD +TF G V DG V D Sbjct: 179 WMEWHPRAPVLLAGTADGNTWMWKVPNGD-CKTFQGPNCPATCGRVLPDGKRAVVGYEDG 237 Query: 287 SARVFDI 267 + R++D+ Sbjct: 238 TIRIWDL 244
>AAMP_HUMAN (Q13685) Angio-associated migratory cell protein| Length = 434 Score = 86.3 bits (212), Expect = 8e-17 Identities = 48/142 (33%), Positives = 72/142 (50%), Gaps = 15/142 (10%) Frame = -2 Query: 653 IVSINSGQVVGSLVGHT---------------NSIECIGISSRYNWVATGSIDRTLIIWD 519 +VS +G+VVG T NS+E +G S A G +D TL I+D Sbjct: 286 LVSATTGKVVGVFRPETVASQPSLGEGEESESNSVESLGFCSVMPLAAVGYLDGTLAIYD 345 Query: 518 LARQAIRSTCEHDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQS 339 LA Q +R C+H G+ L W + V + +DG+VR+WD+ +G L + GH + Sbjct: 346 LATQTLRHQCQHQSGIVQLLWEAGTAVVYTCSLDGIVRLWDARTGRLLTDYRGHTAEILD 405 Query: 338 LAVSADGNSIVSVSTDKSARVF 273 A+S D + +V+ S D A+VF Sbjct: 406 FALSKDASLVVTTSGDHKAKVF 427 Score = 45.4 bits (106), Expect = 1e-04 Identities = 32/127 (25%), Positives = 57/127 (44%), Gaps = 1/127 (0%) Frame = -2 Query: 644 INSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDL-ARQAIRSTCEHDEGVT 468 ++ G+++ GH +S+ C G S VATG + L +W + ++ + S D + Sbjct: 121 LSDGELLFECAGHKDSVTCAGFSHDSTLVATGDMSGLLKVWQVDTKEEVWSFEAGD--LE 178 Query: 467 CLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDK 288 + W + + +G DG +W +GD +TF G V DG V D Sbjct: 179 WMEWHPRAPVLLAGTADGNTWMWKVPNGD-CKTFQGPNCPATCGRVLPDGKRAVVGYEDG 237 Query: 287 SARVFDI 267 + R++D+ Sbjct: 238 TIRIWDL 244
>AAMP_CANFA (Q7YR70) Angio-associated migratory cell protein| Length = 435 Score = 85.1 bits (209), Expect = 2e-16 Identities = 47/142 (33%), Positives = 72/142 (50%), Gaps = 15/142 (10%) Frame = -2 Query: 653 IVSINSGQVVGSLVGHT---------------NSIECIGISSRYNWVATGSIDRTLIIWD 519 +VS +G+VVG T NS+E +G S A G +D TL I+D Sbjct: 287 LVSATTGKVVGVFRPETVASQPNVGEGEESESNSVESLGFCSVMPLAAVGYLDGTLAIYD 346 Query: 518 LARQAIRSTCEHDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQS 339 L+ Q +R C+H G+ L W + V + +DG+VR+WD+ +G L + GH + Sbjct: 347 LSTQTLRHQCQHQSGIVQLLWEAGTAVVYTCSLDGIVRLWDARTGRLLTDYRGHTAEILD 406 Query: 338 LAVSADGNSIVSVSTDKSARVF 273 A+S D + +V+ S D A+VF Sbjct: 407 FALSKDASLVVTTSGDHKAKVF 428 Score = 45.4 bits (106), Expect = 1e-04 Identities = 32/127 (25%), Positives = 57/127 (44%), Gaps = 1/127 (0%) Frame = -2 Query: 644 INSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDL-ARQAIRSTCEHDEGVT 468 ++ G+++ GH +S+ C G S VATG + L +W + ++ + S D + Sbjct: 122 LSDGELLFECAGHKDSVTCAGFSHDSTLVATGDMSGLLKVWQVDTKEEVWSFEAGD--LE 179 Query: 467 CLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDK 288 + W + + +G DG +W +GD +TF G V DG V D Sbjct: 180 WMEWHPRAPVLLAGTADGNTWMWKVPNGD-CKTFQGPNCPATCGRVLPDGKRAVVGYEDG 238 Query: 287 SARVFDI 267 + R++D+ Sbjct: 239 TIRIWDL 245
>TAF5_DROME (P49846) Transcription initiation factor TFIID subunit 5| (Transcription initiation factor TFIID 85 kDa subunit) (p85) (TAFII-80) Length = 704 Score = 84.7 bits (208), Expect = 2e-16 Identities = 42/125 (33%), Positives = 67/125 (53%), Gaps = 1/125 (0%) Frame = -2 Query: 641 NSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWD-LARQAIRSTCEHDEGVTC 465 +S Q + VGH + ++C+ N+VATGS DRT+ +WD + Q++R H V+ Sbjct: 522 DSNQALRVFVGHLSDVDCVQFHPNSNYVATGSSDRTVRLWDNMTGQSVRLMTGHKGSVSS 581 Query: 464 LAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKS 285 LA+ RY+ASG +D + IWD +G L T H V ++ S DG + + D + Sbjct: 582 LAFSACGRYLASGSVDHNIIIWDLSNGSLVTTLLRHTSTVTTITFSRDGTVLAAAGLDNN 641 Query: 284 ARVFD 270 ++D Sbjct: 642 LTLWD 646 Score = 68.9 bits (167), Expect = 1e-11 Identities = 47/176 (26%), Positives = 75/176 (42%), Gaps = 43/176 (24%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDL----------- 516 +V ++ SG+V SL+GHT + + N + + S D T+ +W L Sbjct: 431 NVRMLDDRSGEVTRSLMGHTGPVYRCAFAPEMNLLLSCSEDSTIRLWSLLTWSCVVTYRG 490 Query: 515 --------------------------------ARQAIRSTCEHDEGVTCLAWLGSSRYVA 432 + QA+R H V C+ + +S YVA Sbjct: 491 HVYPVWDVRFAPHGYYFVSCSYDKTARLWATDSNQALRVFVGHLSDVDCVQFHPNSNYVA 550 Query: 431 SGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFDIS 264 +G D VR+WD+++G R +GH+ V SLA SA G + S S D + ++D+S Sbjct: 551 TGSSDRTVRLWDNMTGQSVRLMTGHKGSVSSLAFSACGRYLASGSVDHNIIIWDLS 606 Score = 40.8 bits (94), Expect = 0.004 Identities = 29/110 (26%), Positives = 49/110 (44%) Frame = -2 Query: 596 IECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCEHDEGVTCLAWLGSSRYVASGCID 417 + C IS +A G D ++ IW L +R+ + D S R + D Sbjct: 380 VTCAEISDDSTMLACGFGDSSVRIWSLTPAKLRTLKDAD----------SLRELDKESAD 429 Query: 416 GMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFDI 267 VR+ D SG++ R+ GH V A + + N ++S S D + R++ + Sbjct: 430 INVRMLDDRSGEVTRSLMGHTGPVYRCAFAPEMNLLLSCSEDSTIRLWSL 479 Score = 30.4 bits (67), Expect = 4.9 Identities = 13/48 (27%), Positives = 27/48 (56%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWD 519 ++ I +++G +V +L+ HT+++ I S +A +D L +WD Sbjct: 599 NIIIWDLSNGSLVTTLLRHTSTVTTITFSRDGTVLAAAGLDNNLTLWD 646
>TUP1_KLULA (P56094) Transcriptional repressor TUP1| Length = 682 Score = 79.7 bits (195), Expect = 7e-15 Identities = 47/147 (31%), Positives = 79/147 (53%), Gaps = 8/147 (5%) Frame = -2 Query: 659 VHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCEHD 480 + I + + ++V +L GH I + N + +GS DRT+ IWDL T + Sbjct: 430 IRIWDLETKKIVMTLKGHEQDIYSLDYFPSGNKLVSGSGDRTVRIWDLTTGTCSLTLSIE 489 Query: 479 EGVTCLAWL-GSSRYVASGCIDGMVRIWDSLSGDLARTF-------SGHRDVVQSLAVSA 324 +GVT +A G +++A+G +D VR+WDS +G L +GHRD V S+ + Sbjct: 490 DGVTTVAVSPGEGKFIAAGSLDRTVRVWDSDTGFLVERLDSENELGTGHRDSVYSVVFTR 549 Query: 323 DGNSIVSVSTDKSARVFDISMFK*EKS 243 DG +VS S D+S ++++++ +KS Sbjct: 550 DGKGVVSGSLDRSVKLWNLNGLSGQKS 576 Score = 55.1 bits (131), Expect = 2e-07 Identities = 38/111 (34%), Positives = 60/111 (54%), Gaps = 2/111 (1%) Frame = -2 Query: 596 IECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCE-HDEGVTCLAWLGSSRYVASGCI 420 I + S ++ATG+ D+ + IWDL + I T + H++ + L + S + SG Sbjct: 409 IRSVCFSPDGKFLATGAEDKLIRIWDLETKKIVMTLKGHEQDIYSLDYFPSGNKLVSGSG 468 Query: 419 DGMVRIWDSLSGDLARTFSGHRDVVQSLAVS-ADGNSIVSVSTDKSARVFD 270 D VRIWD +G + T S D V ++AVS +G I + S D++ RV+D Sbjct: 469 DRTVRIWDLTTGTCSLTLS-IEDGVTTVAVSPGEGKFIAAGSLDRTVRVWD 518 Score = 50.1 bits (118), Expect = 6e-06 Identities = 23/78 (29%), Positives = 42/78 (53%) Frame = -2 Query: 497 STCEHDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADG 318 ST D + + + +++A+G D ++RIWD + + T GH + SL G Sbjct: 401 STASSDLYIRSVCFSPDGKFLATGAEDKLIRIWDLETKKIVMTLKGHEQDIYSLDYFPSG 460 Query: 317 NSIVSVSTDKSARVFDIS 264 N +VS S D++ R++D++ Sbjct: 461 NKLVSGSGDRTVRIWDLT 478 Score = 49.7 bits (117), Expect = 8e-06 Identities = 31/103 (30%), Positives = 52/103 (50%), Gaps = 8/103 (7%) Frame = -2 Query: 611 GHTNSIECIGISSRYNWVATGSIDRTLIIWDL---ARQAIRSTCE-----HDEGVTCLAW 456 GH +S+ + + V +GS+DR++ +W+L + Q + CE H + V +A Sbjct: 537 GHRDSVYSVVFTRDGKGVVSGSLDRSVKLWNLNGLSGQKSHAECEVTYTGHKDFVLSVAT 596 Query: 455 LGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVS 327 + Y+ SG D V WD+ SG+ GHR+ V S+ V+ Sbjct: 597 TQNDEYILSGSKDRGVLFWDTKSGNPLLMLQGHRNSVISVTVA 639
>KTNB1_BRARE (Q7ZUV2) Katanin p80 WD40-containing subunit B1 homolog| Length = 694 Score = 79.3 bits (194), Expect = 9e-15 Identities = 40/132 (30%), Positives = 71/132 (53%), Gaps = 1/132 (0%) Frame = -2 Query: 659 VHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDL-ARQAIRSTCEH 483 V+I +++ + SL GHT+++ CI +S V GS+ +L +WDL A + +R+ H Sbjct: 45 VNIWAVSKPNCIMSLTGHTSAVGCIQFNSSEERVVAGSLSGSLRLWDLEAAKILRTLMGH 104 Query: 482 DEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVS 303 ++ L + Y+ASG +D +++WD + GH V+ LA S DG + S Sbjct: 105 KASISSLDFHPMGEYLASGSVDSNIKLWDVRRKGCVFRYKGHTQAVRCLAFSPDGKWLAS 164 Query: 302 VSTDKSARVFDI 267 S D + +++D+ Sbjct: 165 ASDDSTVKLWDL 176 Score = 70.1 bits (170), Expect = 6e-12 Identities = 33/136 (24%), Positives = 72/136 (52%), Gaps = 1/136 (0%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCE- 486 S+ + + + +++ +L+GH SI + ++A+GS+D + +WD+ R+ + Sbjct: 86 SLRLWDLEAAKILRTLMGHKASISSLDFHPMGEYLASGSVDSNIKLWDVRRKGCVFRYKG 145 Query: 485 HDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIV 306 H + V CLA+ +++AS D V++WD ++G + F+ H V + + + Sbjct: 146 HTQAVRCLAFSPDGKWLASASDDSTVKLWDLIAGKMITEFTSHTSAVNVVQFHPNEYLLA 205 Query: 305 SVSTDKSARVFDISMF 258 S S D++ +++D+ F Sbjct: 206 SGSADRTVKLWDLEKF 221 Score = 59.7 bits (143), Expect = 8e-09 Identities = 33/114 (28%), Positives = 59/114 (51%), Gaps = 1/114 (0%) Frame = -2 Query: 611 GHTNSIECIGISSRYNWVATGSIDRTLIIWDL-ARQAIRSTCEHDEGVTCLAWLGSSRYV 435 GHT ++ C+ S W+A+ S D T+ +WDL A + I H V + + + + Sbjct: 145 GHTQAVRCLAFSPDGKWLASASDDSTVKLWDLIAGKMITEFTSHTSAVNVVQFHPNEYLL 204 Query: 434 ASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVF 273 ASG D V++WD ++ + G VV+S+ + DG+ + S ++ + RV+ Sbjct: 205 ASGSADRTVKLWDLEKFNMIGSSEGETGVVRSVLFNPDGSCLYS-GSENTLRVY 257 Score = 36.2 bits (82), Expect = 0.090 Identities = 16/64 (25%), Positives = 35/64 (54%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCEH 483 +V + + +G+++ HT+++ + +A+GS DRT+ +WDL + + + E Sbjct: 170 TVKLWDLIAGKMITEFTSHTSAVNVVQFHPNEYLLASGSADRTVKLWDLEKFNMIGSSEG 229 Query: 482 DEGV 471 + GV Sbjct: 230 ETGV 233 Score = 30.4 bits (67), Expect = 4.9 Identities = 22/79 (27%), Positives = 36/79 (45%), Gaps = 2/79 (2%) Frame = -2 Query: 485 HDEGVTCLAWLGSS--RYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNS 312 H V+ L LG S R +A+G D V IW + + +GH V + ++ Sbjct: 19 HSSNVSSLV-LGKSSGRLLATGGEDCRVNIWAVSKPNCIMSLTGHTSAVGCIQFNSSEER 77 Query: 311 IVSVSTDKSARVFDISMFK 255 +V+ S S R++D+ K Sbjct: 78 VVAGSLSGSLRLWDLEAAK 96
>TAF5L_MOUSE (Q91WQ5) TAF5-like RNA polymerase II p300/CBP-associated| factor-associated factor 65 kDa subunit 5L (PCAF-associated factor 65 beta) (PAF65-beta) Length = 589 Score = 78.6 bits (192), Expect = 2e-14 Identities = 41/116 (35%), Positives = 63/116 (54%), Gaps = 1/116 (0%) Frame = -2 Query: 611 GHTNSIECIGISSRYNWVATGSIDRTLIIWDLAR-QAIRSTCEHDEGVTCLAWLGSSRYV 435 GH ++C+ N++ATGS D+T+ +W + ++R H V L++ + +Y+ Sbjct: 424 GHLADVDCVKFHPNSNYLATGSTDKTVRLWSAQQGNSVRLFTGHRGPVLSLSFSPNGKYL 483 Query: 434 ASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFDI 267 AS D +++WD SG L + GH D + SLA S D I S S D S RV+DI Sbjct: 484 ASAGEDQRLKLWDLASGTLFKELRGHTDSITSLAFSPDSGLIASASMDNSVRVWDI 539 Score = 68.6 bits (166), Expect = 2e-11 Identities = 38/117 (32%), Positives = 62/117 (52%), Gaps = 1/117 (0%) Frame = -2 Query: 611 GHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQ-AIRSTCEHDEGVTCLAWLGSSRYV 435 GH + + IS + A+GS DRT +W R +R H V C+ + +S Y+ Sbjct: 382 GHAYPVWDVDISPFSLYFASGSHDRTARLWSFDRTYPLRIYAGHLADVDCVKFHPNSNYL 441 Query: 434 ASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFDIS 264 A+G D VR+W + G+ R F+GHR V SL+ S +G + S D+ +++D++ Sbjct: 442 ATGSTDKTVRLWSAQQGNSVRLFTGHRGPVLSLSFSPNGKYLASAGEDQRLKLWDLA 498 Score = 50.1 bits (118), Expect = 6e-06 Identities = 35/138 (25%), Positives = 60/138 (43%), Gaps = 12/138 (8%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAI-RSTCE 486 +V + S G V GH + + S ++A+ D+ L +WDLA + + Sbjct: 449 TVRLWSAQQGNSVRLFTGHRGPVLSLSFSPNGKYLASAGEDQRLKLWDLASGTLFKELRG 508 Query: 485 HDEGVTCLAWLGSSRYVASGCIDGMVRIW-----------DSLSGDLARTFSGHRDVVQS 339 H + +T LA+ S +AS +D VR+W D SG+L ++G V S Sbjct: 509 HTDSITSLAFSPDSGLIASASMDNSVRVWDIRSTCCNTPADGSSGELVGVYTGQMSNVLS 568 Query: 338 LAVSADGNSIVSVSTDKS 285 + A +V+ T ++ Sbjct: 569 VQFMACNLLLVTGITQEN 586
>PKWA_THECU (P49695) Probable serine/threonine-protein kinase pkwA (EC| 2.7.11.1) Length = 742 Score = 78.2 bits (191), Expect = 2e-14 Identities = 44/136 (32%), Positives = 72/136 (52%), Gaps = 1/136 (0%) Frame = -2 Query: 659 VHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCE-H 483 +H+ + SG + +L GHT+ + + S +A+GS D T+ +WD+A R+ E H Sbjct: 483 IHVWDVASGDELHTLEGHTDWVRAVAFSPDGALLASGSDDATVRLWDVAAAEERAVFEGH 542 Query: 482 DEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVS 303 V +A+ VASG DG R+W+ +G GH D V ++A S DG+ + S Sbjct: 543 THYVLDIAFSPDGSMVASGSRDGTARLWNVATGTEHAVLKGHTDYVYAVAFSPDGSMVAS 602 Query: 302 VSTDKSARVFDISMFK 255 S D + R++D++ K Sbjct: 603 GSRDGTIRLWDVATGK 618 Score = 71.2 bits (173), Expect = 3e-12 Identities = 42/129 (32%), Positives = 68/129 (52%), Gaps = 1/129 (0%) Frame = -2 Query: 647 SINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCEHD-EGV 471 ++ +G L GHT+ + + S + VA+GS D T+ +WD+A R + E V Sbjct: 571 NVATGTEHAVLKGHTDYVYAVAFSPDGSMVASGSRDGTIRLWDVATGKERDVLQAPAENV 630 Query: 470 TCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTD 291 LA+ + G D V +WD SG+ TF GH D V+++A S DG + S S D Sbjct: 631 VSLAFSPDGSMLVHGS-DSTVHLWDVASGEALHTFEGHTDWVRAVAFSPDGALLASGSDD 689 Query: 290 KSARVFDIS 264 ++ R++D++ Sbjct: 690 RTIRLWDVA 698 Score = 53.9 bits (128), Expect = 4e-07 Identities = 34/134 (25%), Positives = 65/134 (48%), Gaps = 1/134 (0%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCE- 486 ++ + + +G+ L ++ + S + + GS D T+ +WD+A T E Sbjct: 608 TIRLWDVATGKERDVLQAPAENVVSLAFSPDGSMLVHGS-DSTVHLWDVASGEALHTFEG 666 Query: 485 HDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIV 306 H + V +A+ +ASG D +R+WD + + T GH + V S+A +G ++ Sbjct: 667 HTDWVRAVAFSPDGALLASGSDDRTIRLWDVAAQEEHTTLEGHTEPVHSVAFHPEGTTLA 726 Query: 305 SVSTDKSARVFDIS 264 S S D + R++ I+ Sbjct: 727 SASEDGTIRIWPIA 740 Score = 50.4 bits (119), Expect = 5e-06 Identities = 24/73 (32%), Positives = 39/73 (53%) Frame = -2 Query: 482 DEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVS 303 D +A+ +A G D ++ +WD SGD T GH D V+++A S DG + S Sbjct: 459 DREAVAVAFSPGGSLLAGGSGDKLIHVWDVASGDELHTLEGHTDWVRAVAFSPDGALLAS 518 Query: 302 VSTDKSARVFDIS 264 S D + R++D++ Sbjct: 519 GSDDATVRLWDVA 531
>TAF5L_HUMAN (O75529) TAF5-like RNA polymerase II p300/CBP-associated| factor-associated factor 65 kDa subunit 5L (PCAF-associated factor 65 beta) (PAF65-beta) Length = 589 Score = 77.8 bits (190), Expect = 3e-14 Identities = 41/116 (35%), Positives = 62/116 (53%), Gaps = 1/116 (0%) Frame = -2 Query: 611 GHTNSIECIGISSRYNWVATGSIDRTLIIWDLAR-QAIRSTCEHDEGVTCLAWLGSSRYV 435 GH ++C+ N++ATGS D+T+ +W + ++R H V LA+ + +Y+ Sbjct: 424 GHLADVDCVKFHPNSNYLATGSTDKTVRLWSAQQGNSVRLFTGHRGPVLSLAFSPNGKYL 483 Query: 434 ASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFDI 267 AS D +++WD SG L + GH D + SL S D I S S D S RV+DI Sbjct: 484 ASAGEDQRLKLWDLASGTLYKELRGHTDNITSLTFSPDSGLIASASMDNSVRVWDI 539 Score = 69.7 bits (169), Expect = 7e-12 Identities = 39/117 (33%), Positives = 62/117 (52%), Gaps = 1/117 (0%) Frame = -2 Query: 611 GHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQ-AIRSTCEHDEGVTCLAWLGSSRYV 435 GH + + IS + A+GS DRT +W R +R H V C+ + +S Y+ Sbjct: 382 GHAYPVWDLDISPYSLYFASGSHDRTARLWSFDRTYPLRIYAGHLADVDCVKFHPNSNYL 441 Query: 434 ASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFDIS 264 A+G D VR+W + G+ R F+GHR V SLA S +G + S D+ +++D++ Sbjct: 442 ATGSTDKTVRLWSAQQGNSVRLFTGHRGPVLSLAFSPNGKYLASAGEDQRLKLWDLA 498 Score = 46.6 bits (109), Expect = 7e-05 Identities = 25/90 (27%), Positives = 42/90 (46%), Gaps = 1/90 (1%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAI-RSTCE 486 +V + S G V GH + + S ++A+ D+ L +WDLA + + Sbjct: 449 TVRLWSAQQGNSVRLFTGHRGPVLSLAFSPNGKYLASAGEDQRLKLWDLASGTLYKELRG 508 Query: 485 HDEGVTCLAWLGSSRYVASGCIDGMVRIWD 396 H + +T L + S +AS +D VR+WD Sbjct: 509 HTDNITSLTFSPDSGLIASASMDNSVRVWD 538 Score = 30.8 bits (68), Expect = 3.8 Identities = 13/41 (31%), Positives = 24/41 (58%) Frame = -2 Query: 638 SGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDL 516 SG + L GHT++I + S +A+ S+D ++ +WD+ Sbjct: 499 SGTLYKELRGHTDNITSLTFSPDSGLIASASMDNSVRVWDI 539
>RCO1_NEUCR (P78706) Transcriptional repressor rco-1| Length = 604 Score = 77.8 bits (190), Expect = 3e-14 Identities = 45/135 (33%), Positives = 74/135 (54%), Gaps = 3/135 (2%) Frame = -2 Query: 659 VHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCEHD 480 + + I S + + GH I + S +A+GS DRT+ +WD+ S + Sbjct: 368 IRVWDIQSRTIRNTFHGHEQDIYSLDFSRDGRTIASGSGDRTVRLWDIETGQNTSVLSIE 427 Query: 479 EGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTF---SGHRDVVQSLAVSADGNSI 309 +GVT +A ++VA+G +D VR+WD + G LA GH+D V S+A S DG ++ Sbjct: 428 DGVTTVAISPDKQFVAAGSLDKSVRVWD-MRGYLAERLEGPDGHKDSVYSVAFSPDGRNL 486 Query: 308 VSVSTDKSARVFDIS 264 VS S DK+ +++++S Sbjct: 487 VSGSLDKTIKMWELS 501 Score = 60.8 bits (146), Expect = 3e-09 Identities = 37/146 (25%), Positives = 73/146 (50%), Gaps = 15/146 (10%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLA---RQAIRST 492 +V + I +GQ S++ + + + IS +VA GS+D+++ +WD+ + + Sbjct: 409 TVRLWDIETGQNT-SVLSIEDGVTTVAISPDKQFVAAGSLDKSVRVWDMRGYLAERLEGP 467 Query: 491 CEHDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLS------------GDLARTFSGHRDV 348 H + V +A+ R + SG +D +++W+ + G +TF GHRD Sbjct: 468 DGHKDSVYSVAFSPDGRNLVSGSLDKTIKMWELSAPRGIPSSAPPKGGRCIKTFEGHRDF 527 Query: 347 VQSLAVSADGNSIVSVSTDKSARVFD 270 V S+A++ D ++S S D+ + +D Sbjct: 528 VLSVALTPDSQWVLSGSKDRGVQFWD 553 Score = 57.0 bits (136), Expect = 5e-08 Identities = 36/121 (29%), Positives = 60/121 (49%), Gaps = 7/121 (5%) Frame = -2 Query: 608 HTNSIECIGISSRYNWVATGSIDRTLIIWDLAR-------QAIRSTCEHDEGVTCLAWLG 450 H + + C+ S +VATG +R+ I+D+ Q D + + + Sbjct: 296 HESVVCCVRFSMDGKYVATGC-NRSAQIYDVETGEKLCILQDENIDLTGDLYIRSVCFSP 354 Query: 449 SSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFD 270 +Y+A+G D ++R+WD S + TF GH + SL S DG +I S S D++ R++D Sbjct: 355 DGKYLATGAEDKLIRVWDIQSRTIRNTFHGHEQDIYSLDFSRDGRTIASGSGDRTVRLWD 414 Query: 269 I 267 I Sbjct: 415 I 415 Score = 45.4 bits (106), Expect = 1e-04 Identities = 29/108 (26%), Positives = 52/108 (48%), Gaps = 13/108 (12%) Frame = -2 Query: 611 GHTNSIECIGISSRYNWVATGSIDRTLIIWDLAR-------------QAIRSTCEHDEGV 471 GH +S+ + S + +GS+D+T+ +W+L+ + I++ H + V Sbjct: 469 GHKDSVYSVAFSPDGRNLVSGSLDKTIKMWELSAPRGIPSSAPPKGGRCIKTFEGHRDFV 528 Query: 470 TCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVS 327 +A S++V SG D V+ WD +G GH++ V S+A S Sbjct: 529 LSVALTPDSQWVLSGSKDRGVQFWDPRTGHTQLMLQGHKNSVISVAPS 576
>Y2800_ANASP (Q8YTC2) Hypothetical WD-repeat protein alr2800| Length = 1258 Score = 77.4 bits (189), Expect = 4e-14 Identities = 38/132 (28%), Positives = 76/132 (57%), Gaps = 1/132 (0%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLAR-QAIRSTCE 486 ++ + I G + +L GHT+ + C+ S N +A+ + D T+ +WD+++ + +R+ Sbjct: 749 TIKLWDIQDGTCLQTLTGHTDWVRCVAFSPDGNTLASSAADHTIKLWDVSQGKCLRTLKS 808 Query: 485 HDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIV 306 H V +A+ + +ASG D ++IW+ +G+ +T+ GH + V S+A S D +V Sbjct: 809 HTGWVRSVAFSADGQTLASGSGDRTIKIWNYHTGECLKTYIGHTNSVYSIAYSPDSKILV 868 Query: 305 SVSTDKSARVFD 270 S S D++ +++D Sbjct: 869 SGSGDRTIKLWD 880 Score = 75.1 bits (183), Expect = 2e-13 Identities = 39/132 (29%), Positives = 72/132 (54%), Gaps = 1/132 (0%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLAR-QAIRSTCE 486 SV + +I++GQ L+ HT+ + + + +ATGS D T+ +W+++ Q +++ E Sbjct: 1001 SVRLWNISTGQCFQILLEHTDWVYAVVFHPQGKIIATGSADCTVKLWNISTGQCLKTLSE 1060 Query: 485 HDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIV 306 H + + +AW + +AS D VR+WD +G GH + V S S +G I Sbjct: 1061 HSDKILGMAWSPDGQLLASASADQSVRLWDCCTGRCVGILRGHSNRVYSAIFSPNGEIIA 1120 Query: 305 SVSTDKSARVFD 270 + STD++ +++D Sbjct: 1121 TCSTDQTVKIWD 1132 Score = 69.7 bits (169), Expect = 7e-12 Identities = 35/132 (26%), Positives = 69/132 (52%), Gaps = 1/132 (0%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLAR-QAIRSTCE 486 +V + S+ G + +L GH + + + +A+ S D+T+ +WD+ +++ Sbjct: 707 NVKLWSVRDGVCIKTLTGHEHEVFSVAFHPDGETLASASGDKTIKLWDIQDGTCLQTLTG 766 Query: 485 HDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIV 306 H + V C+A+ +AS D +++WD G RT H V+S+A SADG ++ Sbjct: 767 HTDWVRCVAFSPDGNTLASSAADHTIKLWDVSQGKCLRTLKSHTGWVRSVAFSADGQTLA 826 Query: 305 SVSTDKSARVFD 270 S S D++ ++++ Sbjct: 827 SGSGDRTIKIWN 838 Score = 69.3 bits (168), Expect = 1e-11 Identities = 36/132 (27%), Positives = 72/132 (54%), Gaps = 1/132 (0%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDL-ARQAIRSTCE 486 ++ + ++ G+ + +L HT + + S+ +A+GS DRT+ IW+ + +++ Sbjct: 791 TIKLWDVSQGKCLRTLKSHTGWVRSVAFSADGQTLASGSGDRTIKIWNYHTGECLKTYIG 850 Query: 485 HDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIV 306 H V +A+ S+ + SG D +++WD + +T GH + V S+A S DG ++ Sbjct: 851 HTNSVYSIAYSPDSKILVSGSGDRTIKLWDCQTHICIKTLHGHTNEVCSVAFSPDGQTLA 910 Query: 305 SVSTDKSARVFD 270 VS D+S R+++ Sbjct: 911 CVSLDQSVRLWN 922 Score = 68.9 bits (167), Expect = 1e-11 Identities = 42/133 (31%), Positives = 69/133 (51%), Gaps = 1/133 (0%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLAR-QAIRSTCE 486 SV + +G+ VG L GH+N + S +AT S D+T+ IWD + + +++ Sbjct: 1085 SVRLWDCCTGRCVGILRGHSNRVYSAIFSPNGEIIATCSTDQTVKIWDWQQGKCLKTLTG 1144 Query: 485 HDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIV 306 H V +A+ + +AS D VRIWD +G GH +V S+A S DG + Sbjct: 1145 HTNWVFDIAFSPDGKILASASHDQTVRIWDVNTGKCHHICIGHTHLVSSVAFSPDGEVVA 1204 Query: 305 SVSTDKSARVFDI 267 S S D++ R++++ Sbjct: 1205 SGSQDQTVRIWNV 1217 Score = 63.5 bits (153), Expect = 5e-10 Identities = 43/176 (24%), Positives = 72/176 (40%), Gaps = 43/176 (24%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCEH 483 ++ I + ++G+ + + +GHTNS+ I S + +GS DRT+ +WD T Sbjct: 833 TIKIWNYHTGECLKTYIGHTNSVYSIAYSPDSKILVSGSGDRTIKLWDCQTHICIKTLHG 892 Query: 482 DEGVTCL-------------------------------AWLGSSRY------------VA 432 C AW G++ + +A Sbjct: 893 HTNEVCSVAFSPDGQTLACVSLDQSVRLWNCRTGQCLKAWYGNTDWALPVAFSPDRQILA 952 Query: 431 SGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFDIS 264 SG D V++WD +G + GH D + +A S D ++ S STD S R+++IS Sbjct: 953 SGSNDKTVKLWDWQTGKYISSLEGHTDFIYGIAFSPDSQTLASASTDSSVRLWNIS 1008 Score = 62.4 bits (150), Expect = 1e-09 Identities = 35/136 (25%), Positives = 69/136 (50%), Gaps = 1/136 (0%) Frame = -2 Query: 659 VHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQA-IRSTCEH 483 V + + SG+++ GH+N + + S +A+ D + +W + I++ H Sbjct: 666 VRVWEVKSGKLLLICRGHSNWVRFVVFSPDGEILASCGADENVKLWSVRDGVCIKTLTGH 725 Query: 482 DEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVS 303 + V +A+ +AS D +++WD G +T +GH D V+ +A S DGN++ S Sbjct: 726 EHEVFSVAFHPDGETLASASGDKTIKLWDIQDGTCLQTLTGHTDWVRCVAFSPDGNTLAS 785 Query: 302 VSTDKSARVFDISMFK 255 + D + +++D+S K Sbjct: 786 SAADHTIKLWDVSQGK 801 Score = 53.1 bits (126), Expect = 7e-07 Identities = 35/134 (26%), Positives = 67/134 (50%), Gaps = 1/134 (0%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCE- 486 SV + + +GQ + + G+T+ + S +A+GS D+T+ +WD S+ E Sbjct: 917 SVRLWNCRTGQCLKAWYGNTDWALPVAFSPDRQILASGSNDKTVKLWDWQTGKYISSLEG 976 Query: 485 HDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIV 306 H + + +A+ S+ +AS D VR+W+ +G + H D V ++ G I Sbjct: 977 HTDFIYGIAFSPDSQTLASASTDSSVRLWNISTGQCFQILLEHTDWVYAVVFHPQGKIIA 1036 Query: 305 SVSTDKSARVFDIS 264 + S D + ++++IS Sbjct: 1037 TGSADCTVKLWNIS 1050 Score = 47.4 bits (111), Expect = 4e-05 Identities = 32/104 (30%), Positives = 49/104 (47%), Gaps = 1/104 (0%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTC-E 486 +V I G+ + +L GHTN + I S +A+ S D+T+ IWD+ C Sbjct: 1127 TVKIWDWQQGKCLKTLTGHTNWVFDIAFSPDGKILASASHDQTVRIWDVNTGKCHHICIG 1186 Query: 485 HDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHR 354 H V+ +A+ VASG D VRIW+ +G+ + R Sbjct: 1187 HTHLVSSVAFSPDGEVVASGSQDQTVRIWNVKTGECLQILRAKR 1230 Score = 33.5 bits (75), Expect = 0.58 Identities = 15/51 (29%), Positives = 27/51 (52%) Frame = -2 Query: 419 DGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFDI 267 D VR+W+ SG L GH + V+ + S DG + S D++ +++ + Sbjct: 663 DCHVRVWEVKSGKLLLICRGHSNWVRFVVFSPDGEILASCGADENVKLWSV 713
>TUP1_YEAST (P16649) Glucose repression regulatory protein TUP1 (Flocculation| suppressor protein) (Repressor AER2) Length = 713 Score = 77.0 bits (188), Expect = 5e-14 Identities = 46/139 (33%), Positives = 75/139 (53%), Gaps = 8/139 (5%) Frame = -2 Query: 659 VHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCEHD 480 + I I + ++V L GH I + + + +GS DRT+ IWDL T + Sbjct: 467 IRIWDIENRKIVMILQGHEQDIYSLDYFPSGDKLVSGSGDRTVRIWDLRTGQCSLTLSIE 526 Query: 479 EGVTCLAWL-GSSRYVASGCIDGMVRIWDSLSGDLARTF-------SGHRDVVQSLAVSA 324 +GVT +A G +Y+A+G +D VR+WDS +G L +GH+D V S+ + Sbjct: 527 DGVTTVAVSPGDGKYIAAGSLDRAVRVWDSETGFLVERLDSENESGTGHKDSVYSVVFTR 586 Query: 323 DGNSIVSVSTDKSARVFDI 267 DG S+VS S D+S +++++ Sbjct: 587 DGQSVVSGSLDRSVKLWNL 605 Score = 54.7 bits (130), Expect = 2e-07 Identities = 38/111 (34%), Positives = 59/111 (53%), Gaps = 2/111 (1%) Frame = -2 Query: 596 IECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCE-HDEGVTCLAWLGSSRYVASGCI 420 I + S ++ATG+ DR + IWD+ + I + H++ + L + S + SG Sbjct: 446 IRSVCFSPDGKFLATGAEDRLIRIWDIENRKIVMILQGHEQDIYSLDYFPSGDKLVSGSG 505 Query: 419 DGMVRIWDSLSGDLARTFSGHRDVVQSLAVS-ADGNSIVSVSTDKSARVFD 270 D VRIWD +G + T S D V ++AVS DG I + S D++ RV+D Sbjct: 506 DRTVRIWDLRTGQCSLTLS-IEDGVTTVAVSPGDGKYIAAGSLDRAVRVWD 555 Score = 50.1 bits (118), Expect = 6e-06 Identities = 38/132 (28%), Positives = 61/132 (46%), Gaps = 19/132 (14%) Frame = -2 Query: 611 GHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRS--------TCE-----HDEGV 471 GH +S+ + + V +GS+DR++ +W+L +S TCE H + V Sbjct: 574 GHKDSVYSVVFTRDGQSVVSGSLDRSVKLWNLQNANNKSDSKTPNSGTCEVTYIGHKDFV 633 Query: 470 TCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVS------ADGNSI 309 +A + Y+ SG D V WD SG+ GHR+ V S+AV+ + N Sbjct: 634 LSVATTQNDEYILSGSKDRGVLFWDKKSGNPLLMLQGHRNSVISVAVANGSPLGPEYNVF 693 Query: 308 VSVSTDKSARVF 273 + S D AR++ Sbjct: 694 ATGSGDCKARIW 705 Score = 44.3 bits (103), Expect = 3e-04 Identities = 23/79 (29%), Positives = 40/79 (50%) Frame = -2 Query: 503 IRSTCEHDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSA 324 IRS C +G +++A+G D ++RIWD + + GH + SL Sbjct: 446 IRSVCFSPDG----------KFLATGAEDRLIRIWDIENRKIVMILQGHEQDIYSLDYFP 495 Query: 323 DGNSIVSVSTDKSARVFDI 267 G+ +VS S D++ R++D+ Sbjct: 496 SGDKLVSGSGDRTVRIWDL 514
>Y2124_ANASP (Q8YV57) Hypothetical WD-repeat protein all2124| Length = 1683 Score = 75.9 bits (185), Expect = 1e-13 Identities = 36/131 (27%), Positives = 73/131 (55%), Gaps = 1/131 (0%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCE- 486 +V I + G+ + +L+GH N + + S +A+ S D T+ +W+++ + T + Sbjct: 1427 TVKIWRVRDGKALKTLIGHDNEVNKVNFSPDGKTLASASRDNTVKLWNVSDGKFKKTLKG 1486 Query: 485 HDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIV 306 H + V +++ + +AS D +R+WDS SG+L ++ H D+V S+ + DG+ + Sbjct: 1487 HTDEVFWVSFSPDGKIIASASADKTIRLWDSFSGNLIKSLPAHNDLVYSVNFNPDGSMLA 1546 Query: 305 SVSTDKSARVF 273 S S DK+ +++ Sbjct: 1547 STSADKTVKLW 1557 Score = 74.3 bits (181), Expect = 3e-13 Identities = 42/133 (31%), Positives = 72/133 (54%), Gaps = 1/133 (0%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWD-LARQAIRSTCE 486 +V + +++ G+ +L GHT+ + + S +A+ S D+T+ +WD + I+S Sbjct: 1469 TVKLWNVSDGKFKKTLKGHTDEVFWVSFSPDGKIIASASADKTIRLWDSFSGNLIKSLPA 1528 Query: 485 HDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIV 306 H++ V + + +AS D V++W S G L TFSGH +VV S + S DG I Sbjct: 1529 HNDLVYSVNFNPDGSMLASTSADKTVKLWRSHDGHLLHTFSGHSNVVYSSSFSPDGRYIA 1588 Query: 305 SVSTDKSARVFDI 267 S S DK+ +++ I Sbjct: 1589 SASEDKTVKIWQI 1601 Score = 73.6 bits (179), Expect = 5e-13 Identities = 34/116 (29%), Positives = 65/116 (56%) Frame = -2 Query: 617 LVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCEHDEGVTCLAWLGSSRY 438 L GH + + I IS +A+GS+D+T+ +W + R+ H++ V +++ + Sbjct: 1068 LEGHKDGVISISISRDGQTIASGSLDKTIKLWSRDGRLFRTLNGHEDAVYSVSFSPDGQT 1127 Query: 437 VASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFD 270 +ASG D +++W + G L +T +GH V ++ S DG ++ S S+D S +++D Sbjct: 1128 IASGGSDKTIKLWQTSDGTLLKTITGHEQTVNNVYFSPDGKNLASASSDHSIKLWD 1183 Score = 69.7 bits (169), Expect = 7e-12 Identities = 45/186 (24%), Positives = 91/186 (48%), Gaps = 2/186 (1%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLAR-QAIRSTCE 486 ++ + + G ++ ++ GH ++ + S +A+ S D ++ +WD Q + + Sbjct: 1136 TIKLWQTSDGTLLKTITGHEQTVNNVYFSPDGKNLASASSDHSIKLWDTTSGQLLMTLTG 1195 Query: 485 HDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIV 306 H GV + + + +A+G D V++W G L +T +GH+D V SL+ S DG ++ Sbjct: 1196 HSAGVITVRFSPDGQTIAAGSEDKTVKLWHRQDGKLLKTLNGHQDWVNSLSFSPDGKTLA 1255 Query: 305 SVSTDKSARVFDISMFK*EKS*QQQHG*FGWSFWPVKSGGLLSLYGQELYLQACSHHG-A 129 S S DK+ +++ I+ K K+ + H W G ++ ++ ++ + HG Sbjct: 1256 SASADKTIKLWRIADGKLVKT-LKGHNDSVWDVNFSSDGKAIASASRDNTIKLWNRHGIE 1314 Query: 128 LKTLVG 111 L+T G Sbjct: 1315 LETFTG 1320 Score = 62.0 bits (149), Expect = 2e-09 Identities = 32/122 (26%), Positives = 65/122 (53%), Gaps = 1/122 (0%) Frame = -2 Query: 635 GQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCE-HDEGVTCLA 459 G++ +L GH +++ + S +A+G D+T+ +W + + T H++ V + Sbjct: 1103 GRLFRTLNGHEDAVYSVSFSPDGQTIASGGSDKTIKLWQTSDGTLLKTITGHEQTVNNVY 1162 Query: 458 WLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSAR 279 + + +AS D +++WD+ SG L T +GH V ++ S DG +I + S DK+ + Sbjct: 1163 FSPDGKNLASASSDHSIKLWDTTSGQLLMTLTGHSAGVITVRFSPDGQTIAAGSEDKTVK 1222 Query: 278 VF 273 ++ Sbjct: 1223 LW 1224 Score = 58.5 bits (140), Expect = 2e-08 Identities = 35/123 (28%), Positives = 66/123 (53%), Gaps = 1/123 (0%) Frame = -2 Query: 635 GQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLAR-QAIRSTCEHDEGVTCLA 459 G ++ +L G+ +I I + + + +A+ + D+T+ IW + +A+++ HD V + Sbjct: 1395 GSLLKTLPGN-KAIYGISFTPQGDLIASANADKTVKIWRVRDGKALKTLIGHDNEVNKVN 1453 Query: 458 WLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSAR 279 + + +AS D V++W+ G +T GH D V ++ S DG I S S DK+ R Sbjct: 1454 FSPDGKTLASASRDNTVKLWNVSDGKFKKTLKGHTDEVFWVSFSPDGKIIASASADKTIR 1513 Query: 278 VFD 270 ++D Sbjct: 1514 LWD 1516 Score = 53.1 bits (126), Expect = 7e-07 Identities = 26/74 (35%), Positives = 44/74 (59%) Frame = -2 Query: 485 HDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIV 306 H +GV ++ + +ASG +D +++W S G L RT +GH D V S++ S DG +I Sbjct: 1071 HKDGVISISISRDGQTIASGSLDKTIKLW-SRDGRLFRTLNGHEDAVYSVSFSPDGQTIA 1129 Query: 305 SVSTDKSARVFDIS 264 S +DK+ +++ S Sbjct: 1130 SGGSDKTIKLWQTS 1143 Score = 51.2 bits (121), Expect = 3e-06 Identities = 43/186 (23%), Positives = 84/186 (45%), Gaps = 2/186 (1%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCEH 483 ++ + I G++V +L GH +S+ + SS +A+ S D T+ +W+ + + H Sbjct: 1262 TIKLWRIADGKLVKTLKGHNDSVWDVNFSSDGKAIASASRDNTIKLWNRHGIELETFTGH 1321 Query: 482 DEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVS 303 GV + +L S +AS +D +R+W +G+ V +++ DG+ I + Sbjct: 1322 SGGVYAVNFLPDSNIIASASLDNTIRLWQRPLISPLEVLAGNSG-VYAVSFLHDGSIIAT 1380 Query: 302 VSTDKSARVFDISMFK*EKS*QQQHG*FGWSFWPVKSGGLLSLYGQE--LYLQACSHHGA 129 D + +++ K+ +G SF P G L++ + + + A Sbjct: 1381 AGADGNIQLWHSQDGSLLKTLPGNKAIYGISFTP--QGDLIASANADKTVKIWRVRDGKA 1438 Query: 128 LKTLVG 111 LKTL+G Sbjct: 1439 LKTLIG 1444 Score = 47.4 bits (111), Expect = 4e-05 Identities = 25/106 (23%), Positives = 51/106 (48%) Frame = -2 Query: 560 VATGSIDRTLIIWDLARQAIRSTCEHDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGD 381 +AT D + +W ++ T ++ + +++ +AS D V+IW G Sbjct: 1378 IATAGADGNIQLWHSQDGSLLKTLPGNKAIYGISFTPQGDLIASANADKTVKIWRVRDGK 1437 Query: 380 LARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFDISMFK*EKS 243 +T GH + V + S DG ++ S S D + +++++S K +K+ Sbjct: 1438 ALKTLIGHDNEVNKVNFSPDGKTLASASRDNTVKLWNVSDGKFKKT 1483 Score = 41.6 bits (96), Expect = 0.002 Identities = 19/81 (23%), Positives = 39/81 (48%) Frame = -2 Query: 641 NSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCEHDEGVTCL 462 + G ++ + GH+N + S ++A+ S D+T+ IW + + + +H GV Sbjct: 1560 HDGHLLHTFSGHSNVVYSSSFSPDGRYIASASEDKTVKIWQIDGHLLTTLPQHQAGVMSA 1619 Query: 461 AWLGSSRYVASGCIDGMVRIW 399 + + + SG +D +IW Sbjct: 1620 IFSPDGKTLISGSLDTTTKIW 1640
>TAF5_HUMAN (Q15542) Transcription initiation factor TFIID subunit 5| (Transcription initiation factor TFIID 100 kDa subunit) (TAF(II)100) (TAFII-100) (TAFII100) Length = 800 Score = 75.1 bits (183), Expect = 2e-13 Identities = 40/115 (34%), Positives = 58/115 (50%), Gaps = 1/115 (0%) Frame = -2 Query: 611 GHTNSIECIGISSRYNWVATGSIDRTLIIWDLAR-QAIRSTCEHDEGVTCLAWLGSSRYV 435 GH + C N+VATGS DRT+ +WD+ +R H + L + + R++ Sbjct: 625 GHLADVNCTRFHPNSNYVATGSADRTVRLWDVLNGNCVRIFTGHKGPIHSLTFSPNGRFL 684 Query: 434 ASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFD 270 A+G DG V +WD G + GH D V SL S DG + S S D + R++D Sbjct: 685 ATGATDGRVLLWDIGHGLMVGELKGHTDTVCSLRFSRDGEILASGSMDNTVRLWD 739 Score = 62.4 bits (150), Expect = 1e-09 Identities = 38/133 (28%), Positives = 63/133 (47%), Gaps = 1/133 (0%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLAR-QAIRSTCE 486 +V + S+ + + GH + S + +G DR +W Q +R Sbjct: 566 TVRLWSLQTFTCLVGYKGHNYPVWDTQFSPYGYYFVSGGHDRVARLWATDHYQPLRIFAG 625 Query: 485 HDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIV 306 H V C + +S YVA+G D VR+WD L+G+ R F+GH+ + SL S +G + Sbjct: 626 HLADVNCTRFHPNSNYVATGSADRTVRLWDVLNGNCVRIFTGHKGPIHSLTFSPNGRFLA 685 Query: 305 SVSTDKSARVFDI 267 + +TD ++DI Sbjct: 686 TGATDGRVLLWDI 698 Score = 47.0 bits (110), Expect = 5e-05 Identities = 24/92 (26%), Positives = 45/92 (48%), Gaps = 1/92 (1%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCE- 486 +V + + +G V GH I + S ++ATG+ D +++WD+ + + Sbjct: 650 TVRLWDVLNGNCVRIFTGHKGPIHSLTFSPNGRFLATGATDGRVLLWDIGHGLMVGELKG 709 Query: 485 HDEGVTCLAWLGSSRYVASGCIDGMVRIWDSL 390 H + V L + +ASG +D VR+WD++ Sbjct: 710 HTDTVCSLRFSRDGEILASGSMDNTVRLWDAI 741
>TAF5_MOUSE (Q8C092) Transcription initiation factor TFIID subunit 5| (Transcription initiation factor TFIID 100 kDa subunit) (TAF(II)100) (TAFII-100) (TAFII100) Length = 801 Score = 74.7 bits (182), Expect = 2e-13 Identities = 40/115 (34%), Positives = 58/115 (50%), Gaps = 1/115 (0%) Frame = -2 Query: 611 GHTNSIECIGISSRYNWVATGSIDRTLIIWDLAR-QAIRSTCEHDEGVTCLAWLGSSRYV 435 GH + C N+VATGS DRT+ +WD+ +R H + L + + R++ Sbjct: 626 GHLADVNCTRYHPNSNYVATGSADRTVRLWDVLNGNCVRIFTGHKGPIHSLTFSPNGRFL 685 Query: 434 ASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFD 270 A+G DG V +WD G + GH D V SL S DG + S S D + R++D Sbjct: 686 ATGATDGRVLLWDIGHGLMVGELKGHTDTVCSLRFSRDGEILASGSMDNTVRLWD 740 Score = 62.8 bits (151), Expect = 9e-10 Identities = 38/133 (28%), Positives = 63/133 (47%), Gaps = 1/133 (0%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLAR-QAIRSTCE 486 +V + S+ + + GH + S + +G DR +W Q +R Sbjct: 567 TVRLWSLQTFTCLVGYKGHNYPVWDTQFSPYGYYFVSGGHDRVARLWATDHYQPLRIFAG 626 Query: 485 HDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIV 306 H V C + +S YVA+G D VR+WD L+G+ R F+GH+ + SL S +G + Sbjct: 627 HLADVNCTRYHPNSNYVATGSADRTVRLWDVLNGNCVRIFTGHKGPIHSLTFSPNGRFLA 686 Query: 305 SVSTDKSARVFDI 267 + +TD ++DI Sbjct: 687 TGATDGRVLLWDI 699 Score = 47.0 bits (110), Expect = 5e-05 Identities = 29/109 (26%), Positives = 50/109 (45%), Gaps = 7/109 (6%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCE- 486 +V + + +G V GH I + S ++ATG+ D +++WD+ + + Sbjct: 651 TVRLWDVLNGNCVRIFTGHKGPIHSLTFSPNGRFLATGATDGRVLLWDIGHGLMVGELKG 710 Query: 485 HDEGVTCLAWLGSSRYVASGCIDGMVRIWDS------LSGDLARTFSGH 357 H + V L + +ASG +D VR+WD+ L D T +GH Sbjct: 711 HTDTVCSLRFSRDGEILASGSMDNTVRLWDAVKAFEDLETDDFTTATGH 759
>TUP12_SCHPO (Q9UUG8) Transcriptional repressor tup12| Length = 586 Score = 74.7 bits (182), Expect = 2e-13 Identities = 41/131 (31%), Positives = 69/131 (52%) Frame = -2 Query: 659 VHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCEHD 480 + I I +V L GH I + S + +GS DRT+ +WD+ + D Sbjct: 358 IRIWDIAQKRVYRLLTGHEQEIYSLDFSKDGKTLVSGSGDRTVCLWDVEAGEQKLILHTD 417 Query: 479 EGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSV 300 +GVT + + +++A+G +D ++RIW S SG L GH + V S+A S DG +VS Sbjct: 418 DGVTTVMFSPDGQFIAAGSLDKVIRIWTS-SGTLVEQLHGHEESVYSVAFSPDGKYLVSG 476 Query: 299 STDKSARVFDI 267 S D + +++++ Sbjct: 477 SLDNTIKLWEL 487 Score = 54.3 bits (129), Expect = 3e-07 Identities = 35/136 (25%), Positives = 62/136 (45%), Gaps = 13/136 (9%) Frame = -2 Query: 641 NSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCEHDEGVTC- 465 +SG +V L GH S+ + S ++ +GS+D T+ +W+L + + + EG C Sbjct: 446 SSGTLVEQLHGHEESVYSVAFSPDGKYLVSGSLDNTIKLWELQCVSNVAPSMYKEGGICK 505 Query: 464 ------------LAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSAD 321 + +++ SG D ++ W S T GH + V S+AVS + Sbjct: 506 QTFTGHKDFILSVTVSPDGKWIISGSKDRTIQFWSPDSPHSQLTLQGHNNSVISVAVSPN 565 Query: 320 GNSIVSVSTDKSARVF 273 G+ + S D AR++ Sbjct: 566 GHCFATGSGDLRARIW 581 Score = 51.6 bits (122), Expect = 2e-06 Identities = 35/121 (28%), Positives = 62/121 (51%), Gaps = 7/121 (5%) Frame = -2 Query: 608 HTNSIECIGISSRYNWVATGSIDRTLIIWDLAR-------QAIRSTCEHDEGVTCLAWLG 450 HT+ I + S+ ++ATG +R +++++ Q S E D V +A+ Sbjct: 286 HTSVICYVRFSADGKFLATGC-NRAAMVFNVETGKLITLLQEESSKREGDLYVRSVAFSP 344 Query: 449 SSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFD 270 +Y+A+G D +RIWD + R +GH + SL S DG ++VS S D++ ++D Sbjct: 345 DGKYLATGVEDQQIRIWDIAQKRVYRLLTGHEQEIYSLDFSKDGKTLVSGSGDRTVCLWD 404 Query: 269 I 267 + Sbjct: 405 V 405
>SWD3_SCHPO (O43017) Set1 complex component swd3 (Set1C component swd3)| (COMPASS component swd3) (Complex proteins associated with set1 protein swd3) Length = 380 Score = 74.7 bits (182), Expect = 2e-13 Identities = 38/119 (31%), Positives = 61/119 (51%), Gaps = 1/119 (0%) Frame = -2 Query: 620 SLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTC-EHDEGVTCLAWLGSS 444 +L GH S+ C+ +S W+AT S D T+ IW + T H G++ + W S Sbjct: 49 TLFGHEKSVTCVSVSPNKRWIATSSSDGTIKIWSALTFRLECTLFGHYRGISQVKWATGS 108 Query: 443 RYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFDI 267 +Y+AS D +RIWD R GH + V S+ + G +VS S D++ R++++ Sbjct: 109 KYLASASDDKTIRIWDFEKRCSVRCLKGHTNYVSSIDFNPLGTLLVSGSWDETVRIWNL 167 Score = 49.3 bits (116), Expect = 1e-05 Identities = 29/87 (33%), Positives = 41/87 (47%), Gaps = 1/87 (1%) Frame = -2 Query: 626 VGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLAR-QAIRSTCEHDEGVTCLAWLG 450 V L GHTN + I + + +GS D T+ IW+L +R H E + ++ Sbjct: 131 VRCLKGHTNYVSSIDFNPLGTLLVSGSWDETVRIWNLQDGTCLRMLPAHSEPIISVSISA 190 Query: 449 SSRYVASGCIDGMVRIWDSLSGDLART 369 A+ DGM RIWD LSG +T Sbjct: 191 DGTLCATASYDGMARIWDVLSGQCLKT 217
>CWF17_SCHPO (O94620) Cell cycle control protein cwf17| Length = 340 Score = 73.9 bits (180), Expect = 4e-13 Identities = 40/128 (31%), Positives = 65/128 (50%), Gaps = 1/128 (0%) Frame = -2 Query: 638 SGQVVGSLVGHTNSIECIGISSRYNWVATG-SIDRTLIIWDLARQAIRSTCEHDEGVTCL 462 SGQ + GH + + + + + T S D T+ +WD + T E +T + Sbjct: 124 SGQKIRKHKGHAGVVNALDVLKVGSELLTSVSDDCTMKVWDSRSKDCIKTIEEKYPLTAV 183 Query: 461 AWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSA 282 A V G IDG ++IWD + + GH+D++ SLA+S DG+S++S S D + Sbjct: 184 AIAQQGTQVFIGGIDGAIKIWDLRNNHCSHVLKGHKDIITSLAISKDGSSLLSNSMDNTV 243 Query: 281 RVFDISMF 258 R+FD+ F Sbjct: 244 RIFDVKPF 251 Score = 55.1 bits (131), Expect = 2e-07 Identities = 35/121 (28%), Positives = 59/121 (48%), Gaps = 5/121 (4%) Frame = -2 Query: 617 LVGHTNSIECIGISSRYNWVATGSIDRTLIIW----DLARQAIRSTCEHDEGVTCLAWLG 450 + GHT + ++ A+G +DR +++W D+ + + C+ +T L W Sbjct: 46 MFGHTAEVLVARFDPSGSYFASGGMDRQILLWNVFGDVKNYGVLNGCKG--AITDLQWSR 103 Query: 449 SSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIV-SVSTDKSARVF 273 SR V D + WD++SG R GH VV +L V G+ ++ SVS D + +V+ Sbjct: 104 DSRVVYCSSSDTHLMSWDAVSGQKIRKHKGHAGVVNALDVLKVGSELLTSVSDDCTMKVW 163 Query: 272 D 270 D Sbjct: 164 D 164 Score = 43.1 bits (100), Expect = 7e-04 Identities = 32/120 (26%), Positives = 60/120 (50%), Gaps = 9/120 (7%) Frame = -2 Query: 617 LVGHTNSIECIGISSRYNWVATGSIDRTLIIWDL-----ARQAIR----STCEHDEGVTC 465 L GH + I + IS + + + S+D T+ I+D+ A++ ++ + + + Sbjct: 215 LKGHKDIITSLAISKDGSSLLSNSMDNTVRIFDVKPFASAQRQLQIFEGAIHGQEHNLLG 274 Query: 464 LAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKS 285 +AW +SR+V +G D V +W S +GDL GH V + + I+S S+D++ Sbjct: 275 VAWSRNSRFVGAGSSDKNVYVW-SATGDLRYVLPGHEGSVNHVDFHPHQDIILSCSSDRT 333
>YY46_ANASP (Q8YRI1) Hypothetical WD-repeat protein alr3466| Length = 1526 Score = 73.6 bits (179), Expect = 5e-13 Identities = 40/126 (31%), Positives = 72/126 (57%), Gaps = 1/126 (0%) Frame = -2 Query: 638 SGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLAR-QAIRSTCEHDEGVTCL 462 +G+ + + GH + + +G S +A+GS D+T+ +WD++ Q +++ H V + Sbjct: 895 TGKELLTCKGHNSWVNSVGFSQDGKMLASGSDDQTVRLWDISSGQCLKTFKGHTSRVRSV 954 Query: 461 AWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSA 282 + +S +ASG D VR+WD SG+ F GH V S+A + DG+ + + S D++ Sbjct: 955 VFSPNSLMLASGSSDQTVRLWDISSGECLYIFQGHTGWVYSVAFNLDGSMLATGSGDQTV 1014 Query: 281 RVFDIS 264 R++DIS Sbjct: 1015 RLWDIS 1020 Score = 72.4 bits (176), Expect = 1e-12 Identities = 41/134 (30%), Positives = 70/134 (52%), Gaps = 1/134 (0%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCE- 486 +V + INS + + + GHT+ + + + + +A+GS D+T+ +WD++ T + Sbjct: 1223 TVRLWEINSSKCLCTFQGHTSWVNSVVFNPDGSMLASGSSDKTVRLWDISSSKCLHTFQG 1282 Query: 485 HDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIV 306 H V +A+ +ASG D VR+W+ S TF GH V S+ S DG + Sbjct: 1283 HTNWVNSVAFNPDGSMLASGSGDQTVRLWEISSSKCLHTFQGHTSWVSSVTFSPDGTMLA 1342 Query: 305 SVSTDKSARVFDIS 264 S S D++ R++ IS Sbjct: 1343 SGSDDQTVRLWSIS 1356 Score = 71.6 bits (174), Expect = 2e-12 Identities = 42/134 (31%), Positives = 72/134 (53%), Gaps = 1/134 (0%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLAR-QAIRSTCE 486 +V + I+SGQ + + GHT+ + + S +A+GS D+T+ +WD++ + + Sbjct: 929 TVRLWDISSGQCLKTFKGHTSRVRSVVFSPNSLMLASGSSDQTVRLWDISSGECLYIFQG 988 Query: 485 HDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIV 306 H V +A+ +A+G D VR+WD S F GH V+S+ S+DG + Sbjct: 989 HTGWVYSVAFNLDGSMLATGSGDQTVRLWDISSSQCFYIFQGHTSCVRSVVFSSDGAMLA 1048 Query: 305 SVSTDKSARVFDIS 264 S S D++ R++DIS Sbjct: 1049 SGSDDQTVRLWDIS 1062 Score = 70.9 bits (172), Expect = 3e-12 Identities = 41/133 (30%), Positives = 76/133 (57%), Gaps = 1/133 (0%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCE- 486 +V + SI+SG+ + + +GHTN + + S +A+GS D+T+ +W ++ T + Sbjct: 1349 TVRLWSISSGECLYTFLGHTNWVGSVIFSPDGAILASGSGDQTVRLWSISSGKCLYTLQG 1408 Query: 485 HDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIV 306 H+ V + + +ASG D VR+W+ SG+ T GH + V+S+A S+DG + Sbjct: 1409 HNNWVGSIVFSPDGTLLASGSDDQTVRLWNISSGECLYTLHGHINSVRSVAFSSDGLILA 1468 Query: 305 SVSTDKSARVFDI 267 S S D++ +++D+ Sbjct: 1469 SGSDDETIKLWDV 1481 Score = 70.5 bits (171), Expect = 4e-12 Identities = 41/137 (29%), Positives = 73/137 (53%), Gaps = 1/137 (0%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCE- 486 +V + I+S + + L GHT+ + + + + +A+GS D+T+ +W++ T + Sbjct: 1181 TVRLWDISSSKCLYILQGHTSWVNSVVFNPDGSTLASGSSDQTVRLWEINSSKCLCTFQG 1240 Query: 485 HDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIV 306 H V + + +ASG D VR+WD S TF GH + V S+A + DG+ + Sbjct: 1241 HTSWVNSVVFNPDGSMLASGSSDKTVRLWDISSSKCLHTFQGHTNWVNSVAFNPDGSMLA 1300 Query: 305 SVSTDKSARVFDISMFK 255 S S D++ R+++IS K Sbjct: 1301 SGSGDQTVRLWEISSSK 1317 Score = 70.5 bits (171), Expect = 4e-12 Identities = 42/134 (31%), Positives = 68/134 (50%), Gaps = 1/134 (0%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLAR-QAIRSTCE 486 +V + I+SG+ + GHT + + + + +ATGS D+T+ +WD++ Q Sbjct: 971 TVRLWDISSGECLYIFQGHTGWVYSVAFNLDGSMLATGSGDQTVRLWDISSSQCFYIFQG 1030 Query: 485 HDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIV 306 H V + + +ASG D VR+WD SG+ T GH V+S+ S DG + Sbjct: 1031 HTSCVRSVVFSSDGAMLASGSDDQTVRLWDISSGNCLYTLQGHTSCVRSVVFSPDGAMLA 1090 Query: 305 SVSTDKSARVFDIS 264 S D+ R++DIS Sbjct: 1091 SGGDDQIVRLWDIS 1104 Score = 70.1 bits (170), Expect = 6e-12 Identities = 41/137 (29%), Positives = 73/137 (53%), Gaps = 1/137 (0%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCE- 486 +V + I+S + + + GHTN + + + + +A+GS D+T+ +W+++ T + Sbjct: 1265 TVRLWDISSSKCLHTFQGHTNWVNSVAFNPDGSMLASGSGDQTVRLWEISSSKCLHTFQG 1324 Query: 485 HDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIV 306 H V+ + + +ASG D VR+W SG+ TF GH + V S+ S DG + Sbjct: 1325 HTSWVSSVTFSPDGTMLASGSDDQTVRLWSISSGECLYTFLGHTNWVGSVIFSPDGAILA 1384 Query: 305 SVSTDKSARVFDISMFK 255 S S D++ R++ IS K Sbjct: 1385 SGSGDQTVRLWSISSGK 1401 Score = 66.6 bits (161), Expect = 6e-11 Identities = 41/137 (29%), Positives = 73/137 (53%), Gaps = 1/137 (0%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCE- 486 +V + I+SG + +L GHT+ + + S +A+G D+ + +WD++ T + Sbjct: 1055 TVRLWDISSGNCLYTLQGHTSCVRSVVFSPDGAMLASGGDDQIVRLWDISSGNCLYTLQG 1114 Query: 485 HDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIV 306 + V L + + +A+G D +VR+WD S T GH + V ++A S DG ++ Sbjct: 1115 YTSWVRFLVFSPNGVTLANGSSDQIVRLWDISSKKCLYTLQGHTNWVNAVAFSPDGATLA 1174 Query: 305 SVSTDKSARVFDISMFK 255 S S D++ R++DIS K Sbjct: 1175 SGSGDQTVRLWDISSSK 1191 Score = 65.5 bits (158), Expect = 1e-10 Identities = 39/136 (28%), Positives = 71/136 (52%), Gaps = 1/136 (0%) Frame = -2 Query: 659 VHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCE-H 483 V + I+SG + +L G+T+ + + S +A GS D+ + +WD++ + T + H Sbjct: 1098 VRLWDISSGNCLYTLQGYTSWVRFLVFSPNGVTLANGSSDQIVRLWDISSKKCLYTLQGH 1157 Query: 482 DEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVS 303 V +A+ +ASG D VR+WD S GH V S+ + DG+++ S Sbjct: 1158 TNWVNAVAFSPDGATLASGSGDQTVRLWDISSSKCLYILQGHTSWVNSVVFNPDGSTLAS 1217 Query: 302 VSTDKSARVFDISMFK 255 S+D++ R+++I+ K Sbjct: 1218 GSSDQTVRLWEINSSK 1233 Score = 64.7 bits (156), Expect = 2e-10 Identities = 38/134 (28%), Positives = 69/134 (51%), Gaps = 1/134 (0%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLAR-QAIRSTCE 486 +V + I+S + + + GHT+ + + S +A+GS D+T+ +W ++ + + + Sbjct: 1307 TVRLWEISSSKCLHTFQGHTSWVSSVTFSPDGTMLASGSDDQTVRLWSISSGECLYTFLG 1366 Query: 485 HDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIV 306 H V + + +ASG D VR+W SG T GH + V S+ S DG + Sbjct: 1367 HTNWVGSVIFSPDGAILASGSGDQTVRLWSISSGKCLYTLQGHNNWVGSIVFSPDGTLLA 1426 Query: 305 SVSTDKSARVFDIS 264 S S D++ R+++IS Sbjct: 1427 SGSDDQTVRLWNIS 1440 Score = 50.8 bits (120), Expect = 4e-06 Identities = 28/104 (26%), Positives = 56/104 (53%), Gaps = 1/104 (0%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLAR-QAIRSTCE 486 +V + SI+SG+ + +L GH N + I S +A+GS D+T+ +W+++ + + + Sbjct: 1391 TVRLWSISSGKCLYTLQGHNNWVGSIVFSPDGTLLASGSDDQTVRLWNISSGECLYTLHG 1450 Query: 485 HDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHR 354 H V +A+ +ASG D +++WD +G+ +T + Sbjct: 1451 HINSVRSVAFSSDGLILASGSDDETIKLWDVKTGECIKTLKSEK 1494 Score = 46.6 bits (109), Expect = 7e-05 Identities = 24/70 (34%), Positives = 38/70 (54%) Frame = -2 Query: 473 VTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVST 294 V +A+ + A+G G+VR W++ +G T GH V S+ S DG + S S Sbjct: 867 VLTVAFSPDGKLFATGDSGGIVRFWEAATGKELLTCKGHNSWVNSVGFSQDGKMLASGSD 926 Query: 293 DKSARVFDIS 264 D++ R++DIS Sbjct: 927 DQTVRLWDIS 936
>WDR57_MOUSE (Q6PE01) WD-repeat protein 57| Length = 358 Score = 73.2 bits (178), Expect = 7e-13 Identities = 41/136 (30%), Positives = 72/136 (52%), Gaps = 1/136 (0%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIE-CIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCE 486 +V + +G+ V L GHT+ + C V TGS D T+ +WD+ ++A T + Sbjct: 133 TVAVWDSETGERVKRLKGHTSFVNSCYPARRGPQLVCTGSDDGTVKLWDIRKKAAVQTFQ 192 Query: 485 HDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIV 306 + V + + +S + SG ID +++WD L T GH D V L++S++G+ ++ Sbjct: 193 NTYQVLAVTFNDTSDQIISGGIDNDIKVWDLRQNKLTYTMRGHADSVTGLSLSSEGSYLL 252 Query: 305 SVSTDKSARVFDISMF 258 S + D + RV+D+ F Sbjct: 253 SNAMDNTVRVWDVRPF 268 Score = 53.9 bits (128), Expect = 4e-07 Identities = 28/133 (21%), Positives = 62/133 (46%), Gaps = 9/133 (6%) Frame = -2 Query: 659 VHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTC--- 489 + + + ++ ++ GH +S+ + +SS +++ + ++D T+ +WD+ A + C Sbjct: 218 IKVWDLRQNKLTYTMRGHADSVTGLSLSSEGSYLLSNAMDNTVRVWDVRPFAPKERCVKI 277 Query: 488 ------EHDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVS 327 ++ + +W +A+G D V +WD+ S + GH + +A Sbjct: 278 FQGNVHNFEKNLLRCSWSPDGSKIAAGSADRFVYVWDTTSRRVLYKLPGHAGSINEVAFH 337 Query: 326 ADGNSIVSVSTDK 288 D I+S S+DK Sbjct: 338 PDEPIILSASSDK 350 Score = 42.0 bits (97), Expect = 0.002 Identities = 28/120 (23%), Positives = 50/120 (41%), Gaps = 3/120 (2%) Frame = -2 Query: 617 LVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQA--IRSTCEHDEGVTCLAWLGSS 444 L GH + C + +A+ DR +++W++ + H V L + Sbjct: 63 LSGHEGEVYCCKFHPNGSTLASAGFDRLILLWNVYGDCDNYATLKGHSGAVMELHYNTDG 122 Query: 443 RYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSV-STDKSARVFDI 267 + S D V +WDS +G+ + GH V S + G +V S D + +++DI Sbjct: 123 SMLFSASTDKTVAVWDSETGERVKRLKGHTSFVNSCYPARRGPQLVCTGSDDGTVKLWDI 182
>PK1IP_XENLA (Q68FJ6) p21-activated protein kinase-interacting protein 1-like| (PAK1-interacting protein 1-like) Length = 363 Score = 73.2 bits (178), Expect = 7e-13 Identities = 37/115 (32%), Positives = 69/115 (60%), Gaps = 1/115 (0%) Frame = -2 Query: 608 HTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCEHDEG-VTCLAWLGSSRYVA 432 HT S+ + +++R+ VATGS D T+ I+D+ ++ H G +TCL + G++ ++ Sbjct: 39 HTASVSVLAVNNRF--VATGSRDETIQIYDMKKKVEHGALLHHNGTITCLEFYGNT-HLL 95 Query: 431 SGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFDI 267 SG DG++ +W++ + +TF H+ V SL++ G +SV TDK+ R +++ Sbjct: 96 SGAEDGLICVWNTKKWECQQTFKAHKGQVLSLSIHPSGKLALSVGTDKTLRTWNL 150
>WDR57_PONPY (Q5RF51) WD-repeat protein 57| Length = 357 Score = 73.2 bits (178), Expect = 7e-13 Identities = 41/136 (30%), Positives = 72/136 (52%), Gaps = 1/136 (0%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIE-CIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCE 486 +V + +G+ V L GHT+ + C V TGS D T+ +WD+ ++A T + Sbjct: 132 TVAVWDSETGERVKRLKGHTSFVNSCYPARRGPQLVCTGSDDGTVKLWDIRKKAAIQTFQ 191 Query: 485 HDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIV 306 + V + + +S + SG ID +++WD L T GH D V L++S++G+ ++ Sbjct: 192 NTYQVLAVTFNDTSDQIISGGIDNDIKVWDLRQNKLTYTMRGHADSVTGLSLSSEGSYLL 251 Query: 305 SVSTDKSARVFDISMF 258 S + D + RV+D+ F Sbjct: 252 SNAMDNTVRVWDVRPF 267 Score = 54.3 bits (129), Expect = 3e-07 Identities = 28/133 (21%), Positives = 62/133 (46%), Gaps = 9/133 (6%) Frame = -2 Query: 659 VHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTC--- 489 + + + ++ ++ GH +S+ + +SS +++ + ++D T+ +WD+ A + C Sbjct: 217 IKVWDLRQNKLTYTMRGHADSVTGLSLSSEGSYLLSNAMDNTVRVWDVRPFAPKERCVKI 276 Query: 488 ------EHDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVS 327 ++ + +W +A+G D V +WD+ S + GH + +A Sbjct: 277 FQGNVHNFEKNLLRCSWSPDGSKIAAGSADRSVCVWDTTSRRILYKLPGHAGSINEVAFH 336 Query: 326 ADGNSIVSVSTDK 288 D I+S S+DK Sbjct: 337 PDEPIIISASSDK 349 Score = 39.7 bits (91), Expect = 0.008 Identities = 27/120 (22%), Positives = 50/120 (41%), Gaps = 3/120 (2%) Frame = -2 Query: 617 LVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQA--IRSTCEHDEGVTCLAWLGSS 444 L GH + C + +A+ DR +++W++ + + V L + Sbjct: 62 LSGHEGEVYCCKFHPNGSTLASAGFDRLILLWNVYGDCGNYATLKGYSGAVMELHYNTDG 121 Query: 443 RYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSV-STDKSARVFDI 267 + S D V +WDS +G+ + GH V S + G +V S D + +++DI Sbjct: 122 SMLFSASTDKTVAVWDSETGERVKRLKGHTSFVNSCYPARRGPQLVCTGSDDGTVKLWDI 181
>WDR57_HUMAN (Q96DI7) WD-repeat protein 57 (Prp8-binding protein) (hPRP8BP) (U5| snRNP-specific 40 kDa protein) (38 kDa splicing factor) Length = 357 Score = 73.2 bits (178), Expect = 7e-13 Identities = 41/136 (30%), Positives = 72/136 (52%), Gaps = 1/136 (0%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIE-CIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCE 486 +V + +G+ V L GHT+ + C V TGS D T+ +WD+ ++A T + Sbjct: 132 TVAVWDSETGERVKRLKGHTSFVNSCYPARRGPQLVCTGSDDGTVKLWDIRKKAAIQTFQ 191 Query: 485 HDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIV 306 + V + + +S + SG ID +++WD L T GH D V L++S++G+ ++ Sbjct: 192 NTYQVLAVTFNDTSDQIISGGIDNDIKVWDLRQNKLTYTMRGHADSVTGLSLSSEGSYLL 251 Query: 305 SVSTDKSARVFDISMF 258 S + D + RV+D+ F Sbjct: 252 SNAMDNTVRVWDVRPF 267 Score = 55.1 bits (131), Expect = 2e-07 Identities = 28/133 (21%), Positives = 62/133 (46%), Gaps = 9/133 (6%) Frame = -2 Query: 659 VHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTC--- 489 + + + ++ ++ GH +S+ + +SS +++ + ++D T+ +WD+ A + C Sbjct: 217 IKVWDLRQNKLTYTMRGHADSVTGLSLSSEGSYLLSNAMDNTVRVWDVRPFAPKERCVKI 276 Query: 488 ------EHDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVS 327 ++ + +W +A+G D V +WD+ S + GH + +A Sbjct: 277 FQGNVHNFEKNLLRCSWSPDGSKIAAGSADRFVYVWDTTSRRILYKLPGHAGSINEVAFH 336 Query: 326 ADGNSIVSVSTDK 288 D I+S S+DK Sbjct: 337 PDEPIIISASSDK 349 Score = 42.0 bits (97), Expect = 0.002 Identities = 28/120 (23%), Positives = 50/120 (41%), Gaps = 3/120 (2%) Frame = -2 Query: 617 LVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQA--IRSTCEHDEGVTCLAWLGSS 444 L GH + C + +A+ DR +++W++ + H V L + Sbjct: 62 LSGHEGEVYCCKFHPNGSTLASAGFDRLILLWNVYGDCDNYATLKGHSGAVMELHYNTDG 121 Query: 443 RYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSV-STDKSARVFDI 267 + S D V +WDS +G+ + GH V S + G +V S D + +++DI Sbjct: 122 SMLFSASTDKTVAVWDSETGERVKRLKGHTSFVNSCYPARRGPQLVCTGSDDGTVKLWDI 181 Score = 40.0 bits (92), Expect = 0.006 Identities = 36/134 (26%), Positives = 57/134 (42%), Gaps = 4/134 (2%) Frame = -2 Query: 485 HDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSG-DLARTFSGHRDVVQSLAVSADGNSI 309 H+ V C + + +AS D ++ +W+ D T GH V L + DG+ + Sbjct: 65 HEGEVYCCKFHPNGSTLASAGFDRLILLWNVYGDCDNYATLKGHSGAVMELHYNTDGSML 124 Query: 308 VSVSTDKSARVFDISMFK*EKS*QQQHG*FGWSFWPVKSGGLLSLYGQE---LYLQACSH 138 S STDK+ V+D + K + H F S +P + G L G + + L Sbjct: 125 FSASTDKTVAVWDSETGERVKR-LKGHTSFVNSCYPARRGPQLVCTGSDDGTVKLWDIRK 183 Query: 137 HGALKTLVGTVLVL 96 A++T T VL Sbjct: 184 KAAIQTFQNTYQVL 197
>LIS1_DROME (Q7KNS3) Lissencephaly-1 homolog (Lissencephaly1) (Dlis1) (DLis-1)| Length = 411 Score = 72.8 bits (177), Expect = 9e-13 Identities = 35/132 (26%), Positives = 76/132 (57%), Gaps = 2/132 (1%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLAR--QAIRSTC 489 ++ I +G+ SL GHT+S++ + ++ +A+ S D ++ +WD + + I++ Sbjct: 131 TIRIWDFETGEYERSLKGHTDSVQDVAFDAQGKLLASCSADLSIKLWDFQQSYECIKTMH 190 Query: 488 EHDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSI 309 HD V+ +A++ + YV S D +++W+ +G +T++GHR+ V+ + V +G+ Sbjct: 191 GHDHNVSSVAFVPAGDYVLSASRDRTIKMWEVATGYCVKTYTGHREWVRMVRVHIEGSIF 250 Query: 308 VSVSTDKSARVF 273 + S D++ RV+ Sbjct: 251 ATCSNDQTIRVW 262 Score = 59.3 bits (142), Expect = 1e-08 Identities = 40/153 (26%), Positives = 68/153 (44%), Gaps = 21/153 (13%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIW-DLARQAIRSTCE 486 ++ + + +G V + GH + + + + AT S D+T+ +W ++ + Sbjct: 216 TIKMWEVATGYCVKTYTGHREWVRMVRVHIEGSIFATCSNDQTIRVWLTNSKDCKVELRD 275 Query: 485 HDEGVTCLAWLGSSR--------------------YVASGCIDGMVRIWDSLSGDLARTF 366 H+ V C+AW + ++ASG D +RIWD G T Sbjct: 276 HEHTVECIAWAPEAAASAINEAAGADNKKGHHQGPFLASGSRDKTIRIWDVSVGLCLLTL 335 Query: 365 SGHRDVVQSLAVSADGNSIVSVSTDKSARVFDI 267 SGH + V+ LA G +VS S DK+ RV+D+ Sbjct: 336 SGHDNWVRGLAFHPGGKYLVSASDDKTIRVWDL 368 Score = 50.1 bits (118), Expect = 6e-06 Identities = 33/121 (27%), Positives = 61/121 (50%), Gaps = 2/121 (1%) Frame = -2 Query: 620 SLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDL-ARQAIRSTCEHDEGVTCLAWLGSS 444 SL GH SI + + + + S D T+ IWD + RS H + V +A+ Sbjct: 103 SLTGHRASITRVIFHPIFALMVSASEDATIRIWDFETGEYERSLKGHTDSVQDVAFDAQG 162 Query: 443 RYVASGCIDGMVRIWD-SLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFDI 267 + +AS D +++WD S + +T GH V S+A G+ ++S S D++ +++++ Sbjct: 163 KLLASCSADLSIKLWDFQQSYECIKTMHGHDHNVSSVAFVPAGDYVLSASRDRTIKMWEV 222 Query: 266 S 264 + Sbjct: 223 A 223 Score = 46.6 bits (109), Expect = 7e-05 Identities = 27/99 (27%), Positives = 50/99 (50%), Gaps = 1/99 (1%) Frame = -2 Query: 563 WVATGSIDRTLIIWDLARQAIRSTCE-HDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLS 387 ++A+GS D+T+ IWD++ T HD V LA+ +Y+ S D +R+WD + Sbjct: 311 FLASGSRDKTIRIWDVSVGLCLLTLSGHDNWVRGLAFHPGGKYLVSASDDKTIRVWDLRN 370 Query: 386 GDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFD 270 +T H+ S+ ++S S D++ +V++ Sbjct: 371 KRCMKTLYAHQHFCTSIDFHKAHPYVISGSVDQTVKVWE 409 Score = 43.5 bits (101), Expect = 6e-04 Identities = 21/90 (23%), Positives = 47/90 (52%), Gaps = 1/90 (1%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLA-RQAIRSTCE 486 ++ I ++ G + +L GH N + + ++ + S D+T+ +WDL ++ +++ Sbjct: 320 TIRIWDVSVGLCLLTLSGHDNWVRGLAFHPGGKYLVSASDDKTIRVWDLRNKRCMKTLYA 379 Query: 485 HDEGVTCLAWLGSSRYVASGCIDGMVRIWD 396 H T + + + YV SG +D V++W+ Sbjct: 380 HQHFCTSIDFHKAHPYVISGSVDQTVKVWE 409
>LIS1_BOVIN (P43033) Platelet-activating factor acetylhydrolase IB alpha| subunit (PAF acetylhydrolase 45 kDa subunit) (PAF-AH 45 kDa subunit) (PAF-AH alpha) (PAFAH alpha) (Lissencephaly-1 protein) (LIS-1) Length = 409 Score = 72.8 bits (177), Expect = 9e-13 Identities = 38/134 (28%), Positives = 73/134 (54%), Gaps = 1/134 (0%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLAR-QAIRSTCE 486 ++ + +G +L GHT+S+E I +A+ S D T+ +WD + IR+ Sbjct: 130 TIKVWDYETGDFERTLKGHTDSVEDISFDHSGKLLASCSADMTIKLWDFQGFECIRTMHG 189 Query: 485 HDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIV 306 HD V+ +A + + ++ S D +++W+ +G +TF+GHR+ V+ + + DG I Sbjct: 190 HDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQTGYCVKTFTGHREWVRMVRPNQDGTLIA 249 Query: 305 SVSTDKSARVFDIS 264 S S D++ RV+ ++ Sbjct: 250 SCSNDQTVRVWVVA 263 Score = 56.6 bits (135), Expect = 6e-08 Identities = 31/119 (26%), Positives = 62/119 (52%), Gaps = 1/119 (0%) Frame = -2 Query: 620 SLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCE-HDEGVTCLAWLGSS 444 +L GH + + + ++ + + S D T+ +WD T + H + V +++ S Sbjct: 102 ALSGHRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLKGHTDSVEDISFDHSG 161 Query: 443 RYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFDI 267 + +AS D +++WD + RT GH V S+A+ +G+ IVS S DK+ +++++ Sbjct: 162 KLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEV 220 Score = 55.8 bits (133), Expect = 1e-07 Identities = 35/152 (23%), Positives = 69/152 (45%), Gaps = 21/152 (13%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTC-E 486 ++ + + +G V + GH + + + +A+ S D+T+ +W +A + ++ E Sbjct: 214 TIKMWEVQTGYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVWVVATKECKAELRE 273 Query: 485 HDEGVTCLAWLGSSRY--------------------VASGCIDGMVRIWDSLSGDLARTF 366 H+ V C++W S Y + SG D +++WD +G T Sbjct: 274 HEHVVECISWAPESSYSSISEATGSETKKSGKPGPFLLSGSRDKTIKMWDVSTGMCLMTL 333 Query: 365 SGHRDVVQSLAVSADGNSIVSVSTDKSARVFD 270 GH + V+ + + G I+S + DK+ RV+D Sbjct: 334 VGHDNWVRGVLFHSGGKFILSCADDKTLRVWD 365 Score = 47.0 bits (110), Expect = 5e-05 Identities = 22/90 (24%), Positives = 52/90 (57%), Gaps = 1/90 (1%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLA-RQAIRSTCE 486 ++ + +++G + +LVGH N + + S ++ + + D+TL +WD ++ +++ Sbjct: 318 TIKMWDVSTGMCLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDYKNKRCMKTLNA 377 Query: 485 HDEGVTCLAWLGSSRYVASGCIDGMVRIWD 396 H+ VT L + ++ YV +G +D V++W+ Sbjct: 378 HEHFVTSLDFHKTAPYVVTGSVDQTVKVWE 407 Score = 44.3 bits (103), Expect = 3e-04 Identities = 18/61 (29%), Positives = 32/61 (52%) Frame = -2 Query: 437 VASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFDISMF 258 + S D +++WD +GD RT GH D V+ ++ G + S S D + +++D F Sbjct: 122 MVSASEDATIKVWDYETGDFERTLKGHTDSVEDISFDHSGKLLASCSADMTIKLWDFQGF 181 Query: 257 K 255 + Sbjct: 182 E 182 Score = 43.9 bits (102), Expect = 4e-04 Identities = 23/99 (23%), Positives = 50/99 (50%), Gaps = 1/99 (1%) Frame = -2 Query: 563 WVATGSIDRTLIIWDLAR-QAIRSTCEHDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLS 387 ++ +GS D+T+ +WD++ + + HD V + + +++ S D +R+WD + Sbjct: 309 FLLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDYKN 368 Query: 386 GDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFD 270 +T + H V SL +V+ S D++ +V++ Sbjct: 369 KRCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVKVWE 407
>TUP11_SCHPO (Q09715) Transcriptional repressor tup11| Length = 614 Score = 72.8 bits (177), Expect = 9e-13 Identities = 37/115 (32%), Positives = 65/115 (56%) Frame = -2 Query: 611 GHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCEHDEGVTCLAWLGSSRYVA 432 GH I + S ++ +GS DRT +WD+ E + GVT +A + +++A Sbjct: 400 GHEQDIYSLDFSHNGRFIVSGSGDRTARLWDVETGQCILKLEIENGVTAIAISPNDQFIA 459 Query: 431 SGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFDI 267 G +D ++R+W S+SG L GH++ V S+A S D + ++S S DK+ +V+++ Sbjct: 460 VGSLDQIIRVW-SVSGTLVERLEGHKESVYSIAFSPDSSILLSGSLDKTIKVWEL 513 Score = 63.2 bits (152), Expect = 7e-10 Identities = 45/139 (32%), Positives = 67/139 (48%), Gaps = 15/139 (10%) Frame = -2 Query: 638 SGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRST----------C 489 SG +V L GH S+ I S + + +GS+D+T+ +W+L QA RS C Sbjct: 473 SGTLVERLEGHKESVYSIAFSPDSSILLSGSLDKTIKVWEL--QATRSVGLSAIKPEGIC 530 Query: 488 E-----HDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSA 324 + H + V +A SR+ SG D ++ WD +G T GH++ V S+ S Sbjct: 531 KATYTGHTDFVLSVAVSPDSRWGLSGSKDRSMQFWDLQTGQSYLTCQGHKNSVISVCFSP 590 Query: 323 DGNSIVSVSTDKSARVFDI 267 DG S S D AR++ I Sbjct: 591 DGRQFASGSGDLRARIWSI 609 Score = 50.8 bits (120), Expect = 4e-06 Identities = 33/122 (27%), Positives = 62/122 (50%), Gaps = 8/122 (6%) Frame = -2 Query: 608 HTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCEHDEG--------VTCLAWL 453 H + + C+ S+ ++ATG ++ ++D+ T H+E V +A+ Sbjct: 312 HPSVVCCVKFSNNGKYLATGC-NQAANVFDVQTGKKLFTL-HEESPDPSRDLYVRTIAFS 369 Query: 452 GSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVF 273 +Y+ +G D +++WD + + FSGH + SL S +G IVS S D++AR++ Sbjct: 370 PDGKYLVTGTEDRQIKLWDLSTQKVRYVFSGHEQDIYSLDFSHNGRFIVSGSGDRTARLW 429 Query: 272 DI 267 D+ Sbjct: 430 DV 431
>SCON2_NEUCR (Q01277) Sulfur controller 2 (SCON2)| Length = 650 Score = 72.0 bits (175), Expect = 1e-12 Identities = 41/127 (32%), Positives = 71/127 (55%), Gaps = 1/127 (0%) Frame = -2 Query: 641 NSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDL-ARQAIRSTCEHDEGVTC 465 NS + L GH N + C+ + N +ATGS D T+ IW++ + IR+ H G+ Sbjct: 282 NSRYKLSVLKGHENGVTCLQLDD--NILATGSYDTTIKIWNIETEECIRTLVGHTAGIRA 339 Query: 464 LAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKS 285 L + S + SG +D +++W+ +G+ TF+ H D V ++V DG+ + S S+DK+ Sbjct: 340 LQFDDSK--LISGSLDHTIKVWNWHTGECLSTFAAHTDSV--ISVHFDGHLLASGSSDKT 395 Query: 284 ARVFDIS 264 ++FD + Sbjct: 396 VKIFDFN 402 Score = 50.4 bits (119), Expect = 5e-06 Identities = 30/77 (38%), Positives = 43/77 (55%), Gaps = 1/77 (1%) Frame = -2 Query: 554 TGSIDRTLIIWDLAR-QAIRSTCEHDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDL 378 TG +D T+ +WD A + +R+ H EGV LA G + V SG DGMV+ W+ SG Sbjct: 553 TGGLDSTMRLWDSATGRCLRTLFGHLEGVWSLA--GDTIRVISGANDGMVKTWEPRSGKC 610 Query: 377 ARTFSGHRDVVQSLAVS 327 T++GH V + +S Sbjct: 611 DATYTGHCGPVTCVGLS 627 Score = 42.7 bits (99), Expect = 0.001 Identities = 27/111 (24%), Positives = 55/111 (49%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCEH 483 ++ + + ++G+ + + HT+S+ I + + +A+GS D+T+ I+D + H Sbjct: 355 TIKVWNWHTGECLSTFAAHTDSV--ISVHFDGHLLASGSSDKTVKIFDFNSKETYCLKGH 412 Query: 482 DEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAV 330 + V SR V S D +++WD + + RT+ GH VQ + + Sbjct: 413 SDWVNSTHVDIKSRTVFSASDDTTIKLWDLDTRQVIRTYEGHVGHVQQVLI 463 Score = 39.7 bits (91), Expect = 0.008 Identities = 23/85 (27%), Positives = 43/85 (50%) Frame = -2 Query: 524 WDLARQAIRSTCEHDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVV 345 W +R + H+ GVTCL +A+G D ++IW+ + + RT GH + Sbjct: 280 WKNSRYKLSVLKGHENGVTCLQL--DDNILATGSYDTTIKIWNIETEECIRTLVGHTAGI 337 Query: 344 QSLAVSADGNSIVSVSTDKSARVFD 270 + A+ D + ++S S D + +V++ Sbjct: 338 R--ALQFDDSKLISGSLDHTIKVWN 360 Score = 38.5 bits (88), Expect = 0.018 Identities = 20/58 (34%), Positives = 32/58 (55%) Frame = -2 Query: 443 RYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFD 270 RY +G +D +R+WDS +G RT GH + V SLA D ++S + D + ++ Sbjct: 549 RYFMTGGLDSTMRLWDSATGRCLRTLFGHLEGVWSLA--GDTIRVISGANDGMVKTWE 604
>PRP46_YARLI (Q6C709) Pre-mRNA-splicing factor PRP46 (Pre-mRNA-processing| protein 46) Length = 472 Score = 71.6 bits (174), Expect = 2e-12 Identities = 42/118 (35%), Positives = 58/118 (49%), Gaps = 1/118 (0%) Frame = -2 Query: 617 LVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCE-HDEGVTCLAWLGSSR 441 + GH + + + W ATGS D+T+ IWDLA +R T H GV L Sbjct: 159 ITGHQGWVRSVCVEPENQWFATGSADKTIKIWDLATGKLRLTLTGHIMGVRALGVSPRHP 218 Query: 440 YVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFDI 267 Y+ SG D MV+ WD + + R + GH V SL + + +VS D ARV+DI Sbjct: 219 YMFSGGEDKMVKCWDLETNKVVRHYHGHLSAVYSLDIHPTLDVLVSAGRDAVARVWDI 276 Score = 56.6 bits (135), Expect = 6e-08 Identities = 31/137 (22%), Positives = 66/137 (48%), Gaps = 1/137 (0%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDL-ARQAIRSTCE 486 ++ I + +G++ +L GH + +G+S R+ ++ +G D+ + WDL + +R Sbjct: 186 TIKIWDLATGKLRLTLTGHIMGVRALGVSPRHPYMFSGGEDKMVKCWDLETNKVVRHYHG 245 Query: 485 HDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIV 306 H V L + + S D + R+WD + D SGH+ + + A ++ Sbjct: 246 HLSAVYSLDIHPTLDVLVSAGRDAVARVWDIRTRDPVVVLSGHKSTINRVKFQASEPQVI 305 Query: 305 SVSTDKSARVFDISMFK 255 + S D++ R++++ K Sbjct: 306 TASADETVRLWNLQAGK 322 Score = 38.9 bits (89), Expect = 0.014 Identities = 24/90 (26%), Positives = 40/90 (44%) Frame = -2 Query: 524 WDLARQAIRSTCEHDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVV 345 W + R H V + +++ A+G D ++IWD +G L T +GH V Sbjct: 149 WHAPWEIYRVITGHQGWVRSVCVEPENQWFATGSADKTIKIWDLATGKLRLTLTGHIMGV 208 Query: 344 QSLAVSADGNSIVSVSTDKSARVFDISMFK 255 ++L VS + S DK + +D+ K Sbjct: 209 RALGVSPRHPYMFSGGEDKMVKCWDLETNK 238 Score = 35.4 bits (80), Expect = 0.15 Identities = 22/99 (22%), Positives = 39/99 (39%) Frame = -2 Query: 617 LVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCEHDEGVTCLAWLGSSRY 438 L GH ++I + + V T S D T+ +W+L +T H + L + Sbjct: 285 LSGHKSTINRVKFQASEPQVITASADETVRLWNLQAGKTMTTLTHHKKSVRGLTLHPEEF 344 Query: 437 VASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSAD 321 S + W GDL + ++ +L+V+ D Sbjct: 345 TFSTASANSSKQWKCPEGDLVLNYDDQNAIINTLSVNQD 383
>KTNB1_STRPU (O61585) Katanin p80 WD40-containing subunit B1 (Katanin p80| subunit B1) (p80 katanin) Length = 690 Score = 71.6 bits (174), Expect = 2e-12 Identities = 39/136 (28%), Positives = 70/136 (51%), Gaps = 1/136 (0%) Frame = -2 Query: 659 VHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLA-RQAIRSTCEH 483 V++ ++ + SL GHT+ ++ + +S V GS T+ I+DL + +R+ H Sbjct: 41 VNLWAVGKQNCIISLSGHTSPVDSVKFNSSEELVVAGSQSGTMKIYDLEPAKIVRTLTGH 100 Query: 482 DEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVS 303 + C+ + +VASG D V++WD T+ GH D V + S DG +V+ Sbjct: 101 RNSIRCMDFHPFGEFVASGSTDTNVKLWDVRRKGCIYTYKGHSDQVNMIKFSPDGKWLVT 160 Query: 302 VSTDKSARVFDISMFK 255 S D + +++D++M K Sbjct: 161 ASEDTTIKLWDLTMGK 176 Score = 63.9 bits (154), Expect = 4e-10 Identities = 33/137 (24%), Positives = 68/137 (49%), Gaps = 1/137 (0%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCE- 486 ++ I + ++V +L GH NSI C+ +VA+GS D + +WD+ R+ T + Sbjct: 82 TMKIYDLEPAKIVRTLTGHRNSIRCMDFHPFGEFVASGSTDTNVKLWDVRRKGCIYTYKG 141 Query: 485 HDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIV 306 H + V + + +++ + D +++WD G L + F H V + + + Sbjct: 142 HSDQVNMIKFSPDGKWLVTASEDTTIKLWDLTMGKLFQEFKNHTGGVTGIEFHPNEFLLA 201 Query: 305 SVSTDKSARVFDISMFK 255 S S+D++ + +D+ F+ Sbjct: 202 SGSSDRTVQFWDLETFQ 218 Score = 50.8 bits (120), Expect = 4e-06 Identities = 31/108 (28%), Positives = 51/108 (47%), Gaps = 1/108 (0%) Frame = -2 Query: 611 GHTNSIECIGISSRYNWVATGSIDRTLIIWDLAR-QAIRSTCEHDEGVTCLAWLGSSRYV 435 GH++ + I S W+ T S D T+ +WDL + + H GVT + + + + Sbjct: 141 GHSDQVNMIKFSPDGKWLVTASEDTTIKLWDLTMGKLFQEFKNHTGGVTGIEFHPNEFLL 200 Query: 434 ASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTD 291 ASG D V+ WD + L + S V+S++ DG+ + S D Sbjct: 201 ASGSSDRTVQFWDLETFQLVSSTSPGASAVRSISFHPDGSYLFCSSQD 248 Score = 33.1 bits (74), Expect = 0.76 Identities = 22/79 (27%), Positives = 37/79 (46%), Gaps = 2/79 (2%) Frame = -2 Query: 485 HDEGVTCLAWLG--SSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNS 312 H V CLA LG S R + +G D V +W + + SGH V S+ ++ Sbjct: 15 HSSNVNCLA-LGPMSGRVMVTGGEDKKVNLWAVGKQNCIISLSGHTSPVDSVKFNSSEEL 73 Query: 311 IVSVSTDKSARVFDISMFK 255 +V+ S + +++D+ K Sbjct: 74 VVAGSQSGTMKIYDLEPAK 92
>LIS1_RAT (P63004) Platelet-activating factor acetylhydrolase IB alpha| subunit (PAF acetylhydrolase 45 kDa subunit) (PAF-AH 45 kDa subunit) (PAF-AH alpha) (PAFAH alpha) (Lissencephaly-1 protein) (LIS-1) Length = 409 Score = 71.6 bits (174), Expect = 2e-12 Identities = 37/134 (27%), Positives = 73/134 (54%), Gaps = 1/134 (0%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLAR-QAIRSTCE 486 ++ + +G +L GHT+S++ I +A+ S D T+ +WD + IR+ Sbjct: 130 TIKVWDYETGDFERTLKGHTDSVQDISFDHSGKLLASCSADMTIKLWDFQGFECIRTMHG 189 Query: 485 HDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIV 306 HD V+ +A + + ++ S D +++W+ +G +TF+GHR+ V+ + + DG I Sbjct: 190 HDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQTGYCVKTFTGHREWVRMVRPNQDGTLIA 249 Query: 305 SVSTDKSARVFDIS 264 S S D++ RV+ ++ Sbjct: 250 SCSNDQTVRVWVVA 263 Score = 56.6 bits (135), Expect = 6e-08 Identities = 31/119 (26%), Positives = 62/119 (52%), Gaps = 1/119 (0%) Frame = -2 Query: 620 SLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCE-HDEGVTCLAWLGSS 444 +L GH + + + ++ + + S D T+ +WD T + H + V +++ S Sbjct: 102 ALSGHRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLKGHTDSVQDISFDHSG 161 Query: 443 RYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFDI 267 + +AS D +++WD + RT GH V S+A+ +G+ IVS S DK+ +++++ Sbjct: 162 KLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEV 220 Score = 55.8 bits (133), Expect = 1e-07 Identities = 35/152 (23%), Positives = 69/152 (45%), Gaps = 21/152 (13%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTC-E 486 ++ + + +G V + GH + + + +A+ S D+T+ +W +A + ++ E Sbjct: 214 TIKMWEVQTGYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVWVVATKECKAELRE 273 Query: 485 HDEGVTCLAWLGSSRY--------------------VASGCIDGMVRIWDSLSGDLARTF 366 H+ V C++W S Y + SG D +++WD +G T Sbjct: 274 HEHVVECISWAPESSYSSISEATGSETKKSGKPGPFLLSGSRDKTIKMWDVSTGMCLMTL 333 Query: 365 SGHRDVVQSLAVSADGNSIVSVSTDKSARVFD 270 GH + V+ + + G I+S + DK+ RV+D Sbjct: 334 VGHDNWVRGVLFHSGGKFILSCADDKTLRVWD 365 Score = 47.0 bits (110), Expect = 5e-05 Identities = 22/90 (24%), Positives = 52/90 (57%), Gaps = 1/90 (1%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLA-RQAIRSTCE 486 ++ + +++G + +LVGH N + + S ++ + + D+TL +WD ++ +++ Sbjct: 318 TIKMWDVSTGMCLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDYKNKRCMKTLNA 377 Query: 485 HDEGVTCLAWLGSSRYVASGCIDGMVRIWD 396 H+ VT L + ++ YV +G +D V++W+ Sbjct: 378 HEHFVTSLDFHKTAPYVVTGSVDQTVKVWE 407 Score = 45.4 bits (106), Expect = 1e-04 Identities = 19/61 (31%), Positives = 32/61 (52%) Frame = -2 Query: 437 VASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFDISMF 258 + S D +++WD +GD RT GH D VQ ++ G + S S D + +++D F Sbjct: 122 MVSASEDATIKVWDYETGDFERTLKGHTDSVQDISFDHSGKLLASCSADMTIKLWDFQGF 181 Query: 257 K 255 + Sbjct: 182 E 182 Score = 43.9 bits (102), Expect = 4e-04 Identities = 23/99 (23%), Positives = 50/99 (50%), Gaps = 1/99 (1%) Frame = -2 Query: 563 WVATGSIDRTLIIWDLAR-QAIRSTCEHDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLS 387 ++ +GS D+T+ +WD++ + + HD V + + +++ S D +R+WD + Sbjct: 309 FLLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDYKN 368 Query: 386 GDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFD 270 +T + H V SL +V+ S D++ +V++ Sbjct: 369 KRCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVKVWE 407
>LIS1_PANTR (Q5IS43) Platelet-activating factor acetylhydrolase IB alpha| subunit (PAF acetylhydrolase 45 kDa subunit) (PAF-AH 45 kDa subunit) (PAF-AH alpha) (PAFAH alpha) (Lissencephaly-1 protein) (LIS-1) Length = 409 Score = 71.6 bits (174), Expect = 2e-12 Identities = 37/134 (27%), Positives = 73/134 (54%), Gaps = 1/134 (0%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLAR-QAIRSTCE 486 ++ + +G +L GHT+S++ I +A+ S D T+ +WD + IR+ Sbjct: 130 TIKVWDYETGDFERTLKGHTDSVQDISFDHSGKLLASCSADMTIKLWDFQGFECIRTMHG 189 Query: 485 HDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIV 306 HD V+ +A + + ++ S D +++W+ +G +TF+GHR+ V+ + + DG I Sbjct: 190 HDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQTGYCVKTFTGHREWVRMVRPNQDGTLIA 249 Query: 305 SVSTDKSARVFDIS 264 S S D++ RV+ ++ Sbjct: 250 SCSNDQTVRVWVVA 263 Score = 56.6 bits (135), Expect = 6e-08 Identities = 31/119 (26%), Positives = 62/119 (52%), Gaps = 1/119 (0%) Frame = -2 Query: 620 SLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCE-HDEGVTCLAWLGSS 444 +L GH + + + ++ + + S D T+ +WD T + H + V +++ S Sbjct: 102 ALSGHRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLKGHTDSVQDISFDHSG 161 Query: 443 RYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFDI 267 + +AS D +++WD + RT GH V S+A+ +G+ IVS S DK+ +++++ Sbjct: 162 KLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEV 220 Score = 55.8 bits (133), Expect = 1e-07 Identities = 35/152 (23%), Positives = 69/152 (45%), Gaps = 21/152 (13%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTC-E 486 ++ + + +G V + GH + + + +A+ S D+T+ +W +A + ++ E Sbjct: 214 TIKMWEVQTGYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVWVVATKECKAELRE 273 Query: 485 HDEGVTCLAWLGSSRY--------------------VASGCIDGMVRIWDSLSGDLARTF 366 H+ V C++W S Y + SG D +++WD +G T Sbjct: 274 HEHVVECISWAPESSYSSISEATGSETKKSGKPGPFLLSGSRDKTIKMWDVSTGMCLMTL 333 Query: 365 SGHRDVVQSLAVSADGNSIVSVSTDKSARVFD 270 GH + V+ + + G I+S + DK+ RV+D Sbjct: 334 VGHDNWVRGVLFHSGGKFILSCADDKTLRVWD 365 Score = 46.6 bits (109), Expect = 7e-05 Identities = 22/90 (24%), Positives = 52/90 (57%), Gaps = 1/90 (1%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLA-RQAIRSTCE 486 ++ + +++G + +LVGH N + + S ++ + + D+TL +WD ++ +++ Sbjct: 318 TIKMWDVSTGMCLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDYKNKRCMKTLNA 377 Query: 485 HDEGVTCLAWLGSSRYVASGCIDGMVRIWD 396 H+ VT L + ++ YV +G +D V++W+ Sbjct: 378 HEHFVTSLDFHKTAPYVVTGFVDQTVKVWE 407 Score = 45.4 bits (106), Expect = 1e-04 Identities = 19/61 (31%), Positives = 32/61 (52%) Frame = -2 Query: 437 VASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFDISMF 258 + S D +++WD +GD RT GH D VQ ++ G + S S D + +++D F Sbjct: 122 MVSASEDATIKVWDYETGDFERTLKGHTDSVQDISFDHSGKLLASCSADMTIKLWDFQGF 181 Query: 257 K 255 + Sbjct: 182 E 182 Score = 41.6 bits (96), Expect = 0.002 Identities = 22/99 (22%), Positives = 49/99 (49%), Gaps = 1/99 (1%) Frame = -2 Query: 563 WVATGSIDRTLIIWDLAR-QAIRSTCEHDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLS 387 ++ +GS D+T+ +WD++ + + HD V + + +++ S D +R+WD + Sbjct: 309 FLLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDYKN 368 Query: 386 GDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFD 270 +T + H V SL +V+ D++ +V++ Sbjct: 369 KRCMKTLNAHEHFVTSLDFHKTAPYVVTGFVDQTVKVWE 407
>LIS1_MOUSE (P63005) Platelet-activating factor acetylhydrolase IB alpha| subunit (PAF acetylhydrolase 45 kDa subunit) (PAF-AH 45 kDa subunit) (PAF-AH alpha) (PAFAH alpha) (Lissencephaly-1 protein) (LIS-1) Length = 409 Score = 71.6 bits (174), Expect = 2e-12 Identities = 37/134 (27%), Positives = 73/134 (54%), Gaps = 1/134 (0%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLAR-QAIRSTCE 486 ++ + +G +L GHT+S++ I +A+ S D T+ +WD + IR+ Sbjct: 130 TIKVWDYETGDFERTLKGHTDSVQDISFDHSGKLLASCSADMTIKLWDFQGFECIRTMHG 189 Query: 485 HDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIV 306 HD V+ +A + + ++ S D +++W+ +G +TF+GHR+ V+ + + DG I Sbjct: 190 HDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQTGYCVKTFTGHREWVRMVRPNQDGTLIA 249 Query: 305 SVSTDKSARVFDIS 264 S S D++ RV+ ++ Sbjct: 250 SCSNDQTVRVWVVA 263 Score = 56.6 bits (135), Expect = 6e-08 Identities = 31/119 (26%), Positives = 62/119 (52%), Gaps = 1/119 (0%) Frame = -2 Query: 620 SLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCE-HDEGVTCLAWLGSS 444 +L GH + + + ++ + + S D T+ +WD T + H + V +++ S Sbjct: 102 ALSGHRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLKGHTDSVQDISFDHSG 161 Query: 443 RYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFDI 267 + +AS D +++WD + RT GH V S+A+ +G+ IVS S DK+ +++++ Sbjct: 162 KLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEV 220 Score = 55.8 bits (133), Expect = 1e-07 Identities = 35/152 (23%), Positives = 69/152 (45%), Gaps = 21/152 (13%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTC-E 486 ++ + + +G V + GH + + + +A+ S D+T+ +W +A + ++ E Sbjct: 214 TIKMWEVQTGYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVWVVATKECKAELRE 273 Query: 485 HDEGVTCLAWLGSSRY--------------------VASGCIDGMVRIWDSLSGDLARTF 366 H+ V C++W S Y + SG D +++WD +G T Sbjct: 274 HEHVVECISWAPESSYSSISEATGSETKKSGKPGPFLLSGSRDKTIKMWDVSTGMCLMTL 333 Query: 365 SGHRDVVQSLAVSADGNSIVSVSTDKSARVFD 270 GH + V+ + + G I+S + DK+ RV+D Sbjct: 334 VGHDNWVRGVLFHSGGKFILSCADDKTLRVWD 365 Score = 47.0 bits (110), Expect = 5e-05 Identities = 22/90 (24%), Positives = 52/90 (57%), Gaps = 1/90 (1%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLA-RQAIRSTCE 486 ++ + +++G + +LVGH N + + S ++ + + D+TL +WD ++ +++ Sbjct: 318 TIKMWDVSTGMCLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDYKNKRCMKTLNA 377 Query: 485 HDEGVTCLAWLGSSRYVASGCIDGMVRIWD 396 H+ VT L + ++ YV +G +D V++W+ Sbjct: 378 HEHFVTSLDFHKTAPYVVTGSVDQTVKVWE 407 Score = 45.4 bits (106), Expect = 1e-04 Identities = 19/61 (31%), Positives = 32/61 (52%) Frame = -2 Query: 437 VASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFDISMF 258 + S D +++WD +GD RT GH D VQ ++ G + S S D + +++D F Sbjct: 122 MVSASEDATIKVWDYETGDFERTLKGHTDSVQDISFDHSGKLLASCSADMTIKLWDFQGF 181 Query: 257 K 255 + Sbjct: 182 E 182 Score = 43.9 bits (102), Expect = 4e-04 Identities = 23/99 (23%), Positives = 50/99 (50%), Gaps = 1/99 (1%) Frame = -2 Query: 563 WVATGSIDRTLIIWDLAR-QAIRSTCEHDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLS 387 ++ +GS D+T+ +WD++ + + HD V + + +++ S D +R+WD + Sbjct: 309 FLLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDYKN 368 Query: 386 GDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFD 270 +T + H V SL +V+ S D++ +V++ Sbjct: 369 KRCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVKVWE 407
>LIS1_HUMAN (P43034) Platelet-activating factor acetylhydrolase IB alpha| subunit (PAF acetylhydrolase 45 kDa subunit) (PAF-AH 45 kDa subunit) (PAF-AH alpha) (PAFAH alpha) (Lissencephaly-1 protein) (LIS-1) Length = 409 Score = 71.6 bits (174), Expect = 2e-12 Identities = 37/134 (27%), Positives = 73/134 (54%), Gaps = 1/134 (0%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLAR-QAIRSTCE 486 ++ + +G +L GHT+S++ I +A+ S D T+ +WD + IR+ Sbjct: 130 TIKVWDYETGDFERTLKGHTDSVQDISFDHSGKLLASCSADMTIKLWDFQGFECIRTMHG 189 Query: 485 HDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIV 306 HD V+ +A + + ++ S D +++W+ +G +TF+GHR+ V+ + + DG I Sbjct: 190 HDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQTGYCVKTFTGHREWVRMVRPNQDGTLIA 249 Query: 305 SVSTDKSARVFDIS 264 S S D++ RV+ ++ Sbjct: 250 SCSNDQTVRVWVVA 263 Score = 56.6 bits (135), Expect = 6e-08 Identities = 31/119 (26%), Positives = 62/119 (52%), Gaps = 1/119 (0%) Frame = -2 Query: 620 SLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCE-HDEGVTCLAWLGSS 444 +L GH + + + ++ + + S D T+ +WD T + H + V +++ S Sbjct: 102 ALSGHRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLKGHTDSVQDISFDHSG 161 Query: 443 RYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFDI 267 + +AS D +++WD + RT GH V S+A+ +G+ IVS S DK+ +++++ Sbjct: 162 KLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEV 220 Score = 55.8 bits (133), Expect = 1e-07 Identities = 35/152 (23%), Positives = 69/152 (45%), Gaps = 21/152 (13%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTC-E 486 ++ + + +G V + GH + + + +A+ S D+T+ +W +A + ++ E Sbjct: 214 TIKMWEVQTGYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVWVVATKECKAELRE 273 Query: 485 HDEGVTCLAWLGSSRY--------------------VASGCIDGMVRIWDSLSGDLARTF 366 H+ V C++W S Y + SG D +++WD +G T Sbjct: 274 HEHVVECISWAPESSYSSISEATGSETKKSGKPGPFLLSGSRDKTIKMWDVSTGMCLMTL 333 Query: 365 SGHRDVVQSLAVSADGNSIVSVSTDKSARVFD 270 GH + V+ + + G I+S + DK+ RV+D Sbjct: 334 VGHDNWVRGVLFHSGGKFILSCADDKTLRVWD 365 Score = 47.0 bits (110), Expect = 5e-05 Identities = 22/90 (24%), Positives = 52/90 (57%), Gaps = 1/90 (1%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLA-RQAIRSTCE 486 ++ + +++G + +LVGH N + + S ++ + + D+TL +WD ++ +++ Sbjct: 318 TIKMWDVSTGMCLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDYKNKRCMKTLNA 377 Query: 485 HDEGVTCLAWLGSSRYVASGCIDGMVRIWD 396 H+ VT L + ++ YV +G +D V++W+ Sbjct: 378 HEHFVTSLDFHKTAPYVVTGSVDQTVKVWE 407 Score = 45.4 bits (106), Expect = 1e-04 Identities = 19/61 (31%), Positives = 32/61 (52%) Frame = -2 Query: 437 VASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFDISMF 258 + S D +++WD +GD RT GH D VQ ++ G + S S D + +++D F Sbjct: 122 MVSASEDATIKVWDYETGDFERTLKGHTDSVQDISFDHSGKLLASCSADMTIKLWDFQGF 181 Query: 257 K 255 + Sbjct: 182 E 182 Score = 43.9 bits (102), Expect = 4e-04 Identities = 23/99 (23%), Positives = 50/99 (50%), Gaps = 1/99 (1%) Frame = -2 Query: 563 WVATGSIDRTLIIWDLAR-QAIRSTCEHDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLS 387 ++ +GS D+T+ +WD++ + + HD V + + +++ S D +R+WD + Sbjct: 309 FLLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDYKN 368 Query: 386 GDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFD 270 +T + H V SL +V+ S D++ +V++ Sbjct: 369 KRCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVKVWE 407
>WDS_DROME (Q9V3J8) Protein will die slowly| Length = 361 Score = 71.6 bits (174), Expect = 2e-12 Identities = 36/119 (30%), Positives = 60/119 (50%), Gaps = 1/119 (0%) Frame = -2 Query: 620 SLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCE-HDEGVTCLAWLGSS 444 +L GHT ++ + S W+A+ S D+ + IW T H G++ +AW S Sbjct: 67 TLAGHTKAVSAVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDS 126 Query: 443 RYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFDI 267 R + SG D +++W+ +G +T GH + V + N IVS S D+S R++D+ Sbjct: 127 RLLVSGSDDKTLKVWELSTGKSLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDV 185 Score = 68.2 bits (165), Expect = 2e-11 Identities = 39/123 (31%), Positives = 64/123 (52%), Gaps = 1/123 (0%) Frame = -2 Query: 635 GQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLAR-QAIRSTCEHDEGVTCLA 459 G+ ++ GH I + SS + +GS D+TL +W+L+ +++++ H V C Sbjct: 104 GKFEKTISGHKLGISDVAWSSDSRLLVSGSDDKTLKVWELSTGKSLKTLKGHSNYVFCCN 163 Query: 458 WLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSAR 279 + S + SG D VRIWD +G +T H D V ++ + DG+ IVS S D R Sbjct: 164 FNPQSNLIVSGSFDESVRIWDVRTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCR 223 Query: 278 VFD 270 ++D Sbjct: 224 IWD 226 Score = 63.5 bits (153), Expect = 5e-10 Identities = 33/138 (23%), Positives = 72/138 (52%), Gaps = 2/138 (1%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDL-ARQAIRSTCE 486 ++ + +++G+ + +L GH+N + C + + N + +GS D ++ IWD+ + +++ Sbjct: 137 TLKVWELSTGKSLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVRTGKCLKTLPA 196 Query: 485 HDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLART-FSGHRDVVQSLAVSADGNSI 309 H + V+ + + + S DG+ RIWD+ SG +T V + S +G I Sbjct: 197 HSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPVSFVKFSPNGKYI 256 Query: 308 VSVSTDKSARVFDISMFK 255 ++ + D + +++D S K Sbjct: 257 LAATLDNTLKLWDYSKGK 274 Score = 50.8 bits (120), Expect = 4e-06 Identities = 23/77 (29%), Positives = 45/77 (58%) Frame = -2 Query: 485 HDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIV 306 H + V+ + + + ++AS D +++IW + G +T SGH+ + +A S+D +V Sbjct: 71 HTKAVSAVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDSRLLV 130 Query: 305 SVSTDKSARVFDISMFK 255 S S DK+ +V+++S K Sbjct: 131 SGSDDKTLKVWELSTGK 147 Score = 46.6 bits (109), Expect = 7e-05 Identities = 29/126 (23%), Positives = 57/126 (45%), Gaps = 5/126 (3%) Frame = -2 Query: 638 SGQVVGSLVGHTNS-IECIGISSRYNWVATGSIDRTLIIWDLAR-QAIRSTCEHDEGVTC 465 SGQ + +L+ N + + S ++ ++D TL +WD ++ + +++ H C Sbjct: 229 SGQCLKTLIDDDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYC 288 Query: 464 LAW---LGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVST 294 + + +++ SG D MV IW+ S ++ + GH D V A N I S + Sbjct: 289 IFANFSVTGGKWIVSGSEDNMVYIWNLQSKEVVQKLQGHTDTVLCTACHPTENIIASAAL 348 Query: 293 DKSARV 276 + + Sbjct: 349 ENDKTI 354
>TAF5_YEAST (P38129) Transcription initiation factor TFIID subunit 5| (TBP-associated factor 5) (TBP-associated factor 90 kDa) (TAFII-90) Length = 798 Score = 71.6 bits (174), Expect = 2e-12 Identities = 35/117 (29%), Positives = 65/117 (55%), Gaps = 2/117 (1%) Frame = -2 Query: 611 GHTNSIECIGISSRYNWVATGSIDRTLIIWDLAR-QAIRSTCEHDEGVTCLAWLGSSRYV 435 GH N ++C+ +V TGS D+T +WD++ ++R H V +A R++ Sbjct: 607 GHLNDVDCVSFHPNGCYVFTGSSDKTCRMWDVSTGDSVRLFLGHTAPVISIAVCPDGRWL 666 Query: 434 ASGCIDGMVRIWDSLSGDLARTFSGH-RDVVQSLAVSADGNSIVSVSTDKSARVFDI 267 ++G DG++ +WD +G + GH ++ + SL+ S +GN ++S D + RV+D+ Sbjct: 667 STGSEDGIINVWDIGTGKRLKQMRGHGKNAIYSLSYSKEGNVLISGGADHTVRVWDL 723 Score = 62.0 bits (149), Expect = 2e-09 Identities = 41/137 (29%), Positives = 66/137 (48%), Gaps = 1/137 (0%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLAR-QAIRSTCE 486 +V + S+++ + S GH + + + S ++ AT S D+T +W +R Sbjct: 548 TVRLWSMDTHTALVSYKGHNHPVWDVSFSPLGHYFATASHDQTARLWSCDHIYPLRIFAG 607 Query: 485 HDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIV 306 H V C+++ + YV +G D R+WD +GD R F GH V S+AV DG + Sbjct: 608 HLNDVDCVSFHPNGCYVFTGSSDKTCRMWDVSTGDSVRLFLGHTAPVISIAVCPDGRWLS 667 Query: 305 SVSTDKSARVFDISMFK 255 + S D V+DI K Sbjct: 668 TGSEDGIINVWDIGTGK 684 Score = 51.6 bits (122), Expect = 2e-06 Identities = 31/120 (25%), Positives = 61/120 (50%), Gaps = 1/120 (0%) Frame = -2 Query: 620 SLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDL-ARQAIRSTCEHDEGVTCLAWLGSS 444 +LVGH+ ++ S ++ +GS D+T+ +W + A+ S H+ V +++ Sbjct: 520 TLVGHSGTVYSTSFSPDNKYLLSGSEDKTVRLWSMDTHTALVSYKGHNHPVWDVSFSPLG 579 Query: 443 RYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFDIS 264 Y A+ D R+W R F+GH + V ++ +G + + S+DK+ R++D+S Sbjct: 580 HYFATASHDQTARLWSCDHIYPLRIFAGHLNDVDCVSFHPNGCYVFTGSSDKTCRMWDVS 639 Score = 40.0 bits (92), Expect = 0.006 Identities = 30/126 (23%), Positives = 52/126 (41%), Gaps = 18/126 (14%) Frame = -2 Query: 596 IECIGISSRYNWVATGSIDRTLIIWDLARQAIRS------TCEHDEGVTCLAWLGSS--- 444 + C+ S A G D + IW L ++ + + DE TC +G S Sbjct: 469 MSCLDFSDDCRIAAAGFQDSYIKIWSLDGSSLNNPNIALNNNDKDEDPTCKTLVGHSGTV 528 Query: 443 ---------RYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTD 291 +Y+ SG D VR+W + ++ GH V ++ S G+ + S D Sbjct: 529 YSTSFSPDNKYLLSGSEDKTVRLWSMDTHTALVSYKGHNHPVWDVSFSPLGHYFATASHD 588 Query: 290 KSARVF 273 ++AR++ Sbjct: 589 QTARLW 594 Score = 37.0 bits (84), Expect = 0.053 Identities = 40/167 (23%), Positives = 66/167 (39%), Gaps = 24/167 (14%) Frame = -2 Query: 539 RTLIIWDLARQAIRSTCEH-----DEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGD-- 381 R I D + A+ S C + ++ ++CL + R A+G D ++IW SL G Sbjct: 442 RDAIKLDNLQLALPSVCMYTFQNTNKDMSCLDFSDDCRIAAAGFQDSYIKIW-SLDGSSL 500 Query: 380 ----------------LARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFDISMFK*E 249 +T GH V S + S D ++S S DK+ R++ + Sbjct: 501 NNPNIALNNNDKDEDPTCKTLVGHSGTVYSTSFSPDNKYLLSGSEDKTVRLWSMDTHTAL 560 Query: 248 KS*Q-QQHG*FGWSFWPVKSGGLLSLYGQELYLQACSHHGALKTLVG 111 S + H + SF P+ + + Q L +C H L+ G Sbjct: 561 VSYKGHNHPVWDVSFSPLGHYFATASHDQTARLWSCDHIYPLRIFAG 607
>PK1IP_HUMAN (Q9NWT1) p21-activated protein kinase-interacting protein 1| (PAK1-interacting protein 1) (PAK/PLC-interacting protein 1) (hPIP1) Length = 392 Score = 71.6 bits (174), Expect = 2e-12 Identities = 37/115 (32%), Positives = 66/115 (57%), Gaps = 1/115 (0%) Frame = -2 Query: 608 HTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCEHDEG-VTCLAWLGSSRYVA 432 HT S+ + ++SR+ V TGS D T+ I+D+ ++ H G +TCL + G+ R++ Sbjct: 41 HTASLSAVAVNSRF--VVTGSKDETIHIYDMKKKIEHGALVHHSGTITCLKFYGN-RHLI 97 Query: 431 SGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFDI 267 SG DG++ IWD+ + ++ H+ V L++ G +SV TDK+ R +++ Sbjct: 98 SGAEDGLICIWDAKKWECLKSIKAHKGQVTFLSIHPSGKLALSVGTDKTLRTWNL 152 Score = 36.6 bits (83), Expect = 0.069 Identities = 24/94 (25%), Positives = 45/94 (47%), Gaps = 1/94 (1%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLAR-QAIRSTCE 486 ++HI + G+LV H+ +I C+ + + +G+ D + IWD + + ++S Sbjct: 63 TIHIYDMKKKIEHGALVHHSGTITCLKFYGNRHLI-SGAEDGLICIWDAKKWECLKSIKA 121 Query: 485 HDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSG 384 H VT L+ S + S D +R W+ + G Sbjct: 122 HKGQVTFLSIHPSGKLALSVGTDKTLRTWNLVEG 155
>WDR5_MOUSE (P61965) WD-repeat protein 5 (BMP2-induced 3-kb gene protein)| (WD-repeat protein BIG-3) Length = 334 Score = 70.9 bits (172), Expect = 3e-12 Identities = 38/123 (30%), Positives = 59/123 (47%), Gaps = 1/123 (0%) Frame = -2 Query: 620 SLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCE-HDEGVTCLAWLGSS 444 +L GHT ++ + S W+A+ S D+ + IW T H G++ +AW S Sbjct: 40 TLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDS 99 Query: 443 RYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFDIS 264 + S D ++IWD SG +T GH + V + N IVS S D+S R++D+ Sbjct: 100 NLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVK 159 Query: 263 MFK 255 K Sbjct: 160 TGK 162 Score = 68.6 bits (166), Expect = 2e-11 Identities = 40/123 (32%), Positives = 63/123 (51%), Gaps = 1/123 (0%) Frame = -2 Query: 635 GQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLAR-QAIRSTCEHDEGVTCLA 459 G+ ++ GH I + SS N + + S D+TL IWD++ + +++ H V C Sbjct: 77 GKFEKTISGHKLGISDVAWSSDSNLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCN 136 Query: 458 WLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSAR 279 + S + SG D VRIWD +G +T H D V ++ + DG+ IVS S D R Sbjct: 137 FNPQSNLIVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCR 196 Query: 278 VFD 270 ++D Sbjct: 197 IWD 199 Score = 65.9 bits (159), Expect = 1e-10 Identities = 35/138 (25%), Positives = 72/138 (52%), Gaps = 2/138 (1%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDL-ARQAIRSTCE 486 ++ I ++SG+ + +L GH+N + C + + N + +GS D ++ IWD+ + +++ Sbjct: 110 TLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTGKCLKTLPA 169 Query: 485 HDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLART-FSGHRDVVQSLAVSADGNSI 309 H + V+ + + + S DG+ RIWD+ SG +T V + S +G I Sbjct: 170 HSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPVSFVKFSPNGKYI 229 Query: 308 VSVSTDKSARVFDISMFK 255 ++ + D + +++D S K Sbjct: 230 LAATLDNTLKLWDYSKGK 247 Score = 47.8 bits (112), Expect = 3e-05 Identities = 29/126 (23%), Positives = 59/126 (46%), Gaps = 5/126 (3%) Frame = -2 Query: 638 SGQVVGSLVGHTNS-IECIGISSRYNWVATGSIDRTLIIWDLAR-QAIRSTCEHDEGVTC 465 SGQ + +L+ N + + S ++ ++D TL +WD ++ + +++ H C Sbjct: 202 SGQCLKTLIDDDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYC 261 Query: 464 LAW---LGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVST 294 + + +++ SG D +V IW+ + ++ + GH DVV S A N I S + Sbjct: 262 IFANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQGHTDVVISTACHPTENIIASAAL 321 Query: 293 DKSARV 276 + + Sbjct: 322 ENDKTI 327
>WDR5_HUMAN (P61964) WD-repeat protein 5 (BMP2-induced 3-kb gene protein)| Length = 334 Score = 70.9 bits (172), Expect = 3e-12 Identities = 38/123 (30%), Positives = 59/123 (47%), Gaps = 1/123 (0%) Frame = -2 Query: 620 SLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCE-HDEGVTCLAWLGSS 444 +L GHT ++ + S W+A+ S D+ + IW T H G++ +AW S Sbjct: 40 TLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDS 99 Query: 443 RYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFDIS 264 + S D ++IWD SG +T GH + V + N IVS S D+S R++D+ Sbjct: 100 NLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVK 159 Query: 263 MFK 255 K Sbjct: 160 TGK 162 Score = 68.6 bits (166), Expect = 2e-11 Identities = 40/123 (32%), Positives = 63/123 (51%), Gaps = 1/123 (0%) Frame = -2 Query: 635 GQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLAR-QAIRSTCEHDEGVTCLA 459 G+ ++ GH I + SS N + + S D+TL IWD++ + +++ H V C Sbjct: 77 GKFEKTISGHKLGISDVAWSSDSNLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCN 136 Query: 458 WLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSAR 279 + S + SG D VRIWD +G +T H D V ++ + DG+ IVS S D R Sbjct: 137 FNPQSNLIVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCR 196 Query: 278 VFD 270 ++D Sbjct: 197 IWD 199 Score = 65.9 bits (159), Expect = 1e-10 Identities = 35/138 (25%), Positives = 72/138 (52%), Gaps = 2/138 (1%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDL-ARQAIRSTCE 486 ++ I ++SG+ + +L GH+N + C + + N + +GS D ++ IWD+ + +++ Sbjct: 110 TLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTGKCLKTLPA 169 Query: 485 HDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLART-FSGHRDVVQSLAVSADGNSI 309 H + V+ + + + S DG+ RIWD+ SG +T V + S +G I Sbjct: 170 HSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPVSFVKFSPNGKYI 229 Query: 308 VSVSTDKSARVFDISMFK 255 ++ + D + +++D S K Sbjct: 230 LAATLDNTLKLWDYSKGK 247 Score = 47.8 bits (112), Expect = 3e-05 Identities = 29/126 (23%), Positives = 59/126 (46%), Gaps = 5/126 (3%) Frame = -2 Query: 638 SGQVVGSLVGHTNS-IECIGISSRYNWVATGSIDRTLIIWDLAR-QAIRSTCEHDEGVTC 465 SGQ + +L+ N + + S ++ ++D TL +WD ++ + +++ H C Sbjct: 202 SGQCLKTLIDDDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYC 261 Query: 464 LAW---LGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVST 294 + + +++ SG D +V IW+ + ++ + GH DVV S A N I S + Sbjct: 262 IFANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQGHTDVVISTACHPTENIIASAAL 321 Query: 293 DKSARV 276 + + Sbjct: 322 ENDKTI 327
>WD51A_MOUSE (Q8JZX3) WD-repeat protein 51A| Length = 405 Score = 70.5 bits (171), Expect = 4e-12 Identities = 41/115 (35%), Positives = 63/115 (54%), Gaps = 2/115 (1%) Frame = -2 Query: 611 GHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQ--AIRSTCEHDEGVTCLAWLGSSRY 438 GH +++ C+ S +A+GS+D TL+IW + Q A R T H + VTC+ + S Sbjct: 17 GHRDAVTCVDFSLNTKHLASGSMDSTLMIWHMKPQSRAYRFT-GHKDAVTCVNFSPSGHL 75 Query: 437 VASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVF 273 +ASG D VRIW + F H V+S+ +DG S+V+ S DK+ +V+ Sbjct: 76 LASGSRDKTVRIWVPNVKGESTVFRAHTATVRSVHFCSDGQSLVTASDDKTVKVW 130 Score = 68.2 bits (165), Expect = 2e-11 Identities = 36/133 (27%), Positives = 70/133 (52%), Gaps = 1/133 (0%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWD-LARQAIRSTCE 486 +V + S + + + SL H N + C S + + S D+T+ +WD +R+ I S CE Sbjct: 126 TVKVWSTHRQRFLFSLTQHINWVRCAKFSPDGRLIVSASDDKTVKLWDKTSRECIHSYCE 185 Query: 485 HDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIV 306 H VT + + S +A+ +D V++WD+ + L + + H V +L+ GN ++ Sbjct: 186 HGGFVTYVDFHPSGTCIAAAGMDNTVKVWDARTHRLLQHYQLHSAAVNALSFHPSGNYLI 245 Query: 305 SVSTDKSARVFDI 267 + S+D + ++ D+ Sbjct: 246 TASSDSTLKILDL 258 Score = 36.2 bits (82), Expect = 0.090 Identities = 22/73 (30%), Positives = 34/73 (46%), Gaps = 1/73 (1%) Frame = -2 Query: 608 HTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCEHDEG-VTCLAWLGSSRYVA 432 H+ ++ + N++ T S D TL I DL + T +G T +A+ + Y A Sbjct: 228 HSAAVNALSFHPSGNYLITASSDSTLKILDLMEGRLLYTLHGHQGPATTVAFSRTGEYFA 287 Query: 431 SGCIDGMVRIWDS 393 SG D V +W S Sbjct: 288 SGGSDEQVMVWKS 300
>SEL10_CAEEL (Q93794) F-box/WD-repeat protein sel-10 (Suppressor/enhancer of| lin-12) (Sel-10 protein) Length = 587 Score = 70.1 bits (170), Expect = 6e-12 Identities = 43/134 (32%), Positives = 74/134 (55%), Gaps = 1/134 (0%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCE- 486 +V + S G ++ +L GHT+++ C+ ++ + TGS D TL +WD+ +T Sbjct: 319 TVKVWSTVDGSLLHTLQGHTSTVRCMAMAGSI--LVTGSRDTTLRVWDVESGRHLATLHG 376 Query: 485 HDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIV 306 H V C+ + G++ V SG D V+IW++ +G RT +GH + V SL ++ + + Sbjct: 377 HHAAVRCVQFDGTT--VVSGGYDFTVKIWNAHTGRCIRTLTGHNNRVYSLLFESERSIVC 434 Query: 305 SVSTDKSARVFDIS 264 S S D S RV+D + Sbjct: 435 SGSLDTSIRVWDFT 448 Score = 66.2 bits (160), Expect = 8e-11 Identities = 40/126 (31%), Positives = 66/126 (52%), Gaps = 1/126 (0%) Frame = -2 Query: 644 INSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCE-HDEGVT 468 I+ G+V+ +LVGHT + IS ++ +GS DRT+ +W ++ T + H V Sbjct: 283 IDKGEVMYTLVGHTGGVWTSQISQCGRYIVSGSTDRTVKVWSTVDGSLLHTLQGHTSTVR 342 Query: 467 CLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDK 288 C+A GS + +G D +R+WD SG T GH V+ V DG ++VS D Sbjct: 343 CMAMAGS--ILVTGSRDTTLRVWDVESGRHLATLHGHHAAVR--CVQFDGTTVVSGGYDF 398 Query: 287 SARVFD 270 + ++++ Sbjct: 399 TVKIWN 404 Score = 60.8 bits (146), Expect = 3e-09 Identities = 41/129 (31%), Positives = 67/129 (51%), Gaps = 4/129 (3%) Frame = -2 Query: 641 NSGQVVGSLV--GHTNS-IECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCE-HDEG 474 N+ ++GS V GH + I C+ I + + TGS D TL +W + + + T H G Sbjct: 241 NANPIMGSAVLRGHEDHVITCMQIHD--DVLVTGSDDNTLKVWCIDKGEVMYTLVGHTGG 298 Query: 473 VTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVST 294 V RY+ SG D V++W ++ G L T GH V+ +A++ G+ +V+ S Sbjct: 299 VWTSQISQCGRYIVSGSTDRTVKVWSTVDGSLLHTLQGHTSTVRCMAMA--GSILVTGSR 356 Query: 293 DKSARVFDI 267 D + RV+D+ Sbjct: 357 DTTLRVWDV 365 Score = 58.5 bits (140), Expect = 2e-08 Identities = 39/143 (27%), Positives = 64/143 (44%), Gaps = 11/143 (7%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCEH 483 +V I + ++G+ + +L GH N + + S + V +GS+D ++ +WD R Sbjct: 399 TVKIWNAHTGRCIRTLTGHNNRVYSLLFESERSIVCSGSLDTSIRVWDFTR--------- 449 Query: 482 DEGVTCLAWLGSSRYVASGC-----------IDGMVRIWDSLSGDLARTFSGHRDVVQSL 336 EG C+A L + SG D VR+WD G SGHR + SL Sbjct: 450 PEGQECVALLQGHTSLTSGMQLRGNILVSCNADSHVRVWDIHEGTCVHMLSGHRSAITSL 509 Query: 335 AVSADGNSIVSVSTDKSARVFDI 267 N + + S D + +++DI Sbjct: 510 QWFG-RNMVATSSDDGTVKLWDI 531 Score = 34.3 bits (77), Expect = 0.34 Identities = 24/63 (38%), Positives = 32/63 (50%), Gaps = 1/63 (1%) Frame = -2 Query: 659 VHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQA-IRSTCEH 483 V + I+ G V L GH ++I + R N VAT S D T+ +WD+ R A IR Sbjct: 485 VRVWDIHEGTCVHMLSGHRSAITSLQWFGR-NMVATSSDDGTVKLWDIERGALIRDLVTL 543 Query: 482 DEG 474 D G Sbjct: 544 DSG 546
>TUP1_CANAL (P56093) Transcriptional repressor TUP1| Length = 514 Score = 69.7 bits (169), Expect = 7e-12 Identities = 40/138 (28%), Positives = 71/138 (51%), Gaps = 7/138 (5%) Frame = -2 Query: 659 VHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCEHD 480 + I +++ +++ L GH I + + + +GS DR++ IWDL T + Sbjct: 281 IRIWDLSTKRIIKILRGHEQDIYSLDFFPDGDRLVSGSGDRSVRIWDLRTSQCSLTLSIE 340 Query: 479 EGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTF-------SGHRDVVQSLAVSAD 321 +GVT +A + +A+G +D VR+WDS +G L +GH D V S+A S + Sbjct: 341 DGVTTVAVSPDGKLIAAGSLDRTVRVWDSTTGFLVERLDSGNENGNGHEDSVYSVAFSNN 400 Query: 320 GNSIVSVSTDKSARVFDI 267 G I S S D++ +++ + Sbjct: 401 GEQIASGSLDRTVKLWHL 418 Score = 61.6 bits (148), Expect = 2e-09 Identities = 42/134 (31%), Positives = 67/134 (50%), Gaps = 10/134 (7%) Frame = -2 Query: 644 INSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDL-ARQAIRSTCE-----H 483 ++SG G+ GH +S+ + S+ +A+GS+DRT+ +W L + +STCE H Sbjct: 378 LDSGNENGN--GHEDSVYSVAFSNNGEQIASGSLDRTVKLWHLEGKSDKKSTCEVTYIGH 435 Query: 482 DEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVS 303 + V + + Y+ SG D V WD SG+ GHR+ V S+AVS + Sbjct: 436 KDFVLSVCCTPDNEYILSGSKDRGVIFWDQASGNPLLMLQGHRNSVISVAVSLNSKGTEG 495 Query: 302 V----STDKSARVF 273 + S D AR++ Sbjct: 496 IFATGSGDCKARIW 509 Score = 47.8 bits (112), Expect = 3e-05 Identities = 31/128 (24%), Positives = 59/128 (46%), Gaps = 14/128 (10%) Frame = -2 Query: 608 HTNSIECIGISSRYNWVATGSIDRTLII----WDLARQAI----------RSTCEHDEGV 471 H++ + C+ S ++ATG T + +L + I +T D + Sbjct: 201 HSSVVCCVRFSRDGKFIATGCNKTTQVFNVTTGELVAKLIDESSNENKDDNTTASGDLYI 260 Query: 470 TCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTD 291 + + + +A+G D ++RIWD + + + GH + SL DG+ +VS S D Sbjct: 261 RSVCFSPDGKLLATGAEDKLIRIWDLSTKRIIKILRGHEQDIYSLDFFPDGDRLVSGSGD 320 Query: 290 KSARVFDI 267 +S R++D+ Sbjct: 321 RSVRIWDL 328 Score = 30.0 bits (66), Expect = 6.5 Identities = 18/89 (20%), Positives = 42/89 (47%), Gaps = 14/89 (15%) Frame = -2 Query: 488 EHDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLA--------------RTFSGHRD 351 +H V C+ + +++A+GC + ++++ +G+L T + Sbjct: 200 DHSSVVCCVRFSRDGKFIATGC-NKTTQVFNVTTGELVAKLIDESSNENKDDNTTASGDL 258 Query: 350 VVQSLAVSADGNSIVSVSTDKSARVFDIS 264 ++S+ S DG + + + DK R++D+S Sbjct: 259 YIRSVCFSPDGKLLATGAEDKLIRIWDLS 287
>UTP13_SCHPO (Q9USN3) Probable U3 small nucleolar RNA-associated protein 13 (U3| snoRNA-associated protein 13) Length = 777 Score = 69.7 bits (169), Expect = 7e-12 Identities = 40/124 (32%), Positives = 61/124 (49%), Gaps = 1/124 (0%) Frame = -2 Query: 641 NSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCE-HDEGVTC 465 ++G+VVG L GH + + +A+GS DRT+ IW++ Q T E H + Sbjct: 495 STGEVVGVLRGHRRGVWACSFNPFSRQLASGSGDRTIRIWNVDTQQCVQTLEGHTGAILK 554 Query: 464 LAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKS 285 L ++ V S DG+V++W SG+ T H D V +LA DG+ +VS D Sbjct: 555 LIYISQGTQVVSAAADGLVKVWSLSSGECVATLDNHEDRVWALASRFDGSLLVSGGADAV 614 Query: 284 ARVF 273 V+ Sbjct: 615 VSVW 618 Score = 60.1 bits (144), Expect = 6e-09 Identities = 37/132 (28%), Positives = 61/132 (46%), Gaps = 3/132 (2%) Frame = -2 Query: 653 IVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCEHDEG 474 I I SG+ + S+ H + + I +ATG + + +WD+A + + G Sbjct: 87 IYEIPSGRRIKSMKAHETPVITMTIDPTNTLLATGGAEGLVKVWDIAGAYVTHSFRGHGG 146 Query: 473 VTCLAWLGSSR---YVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVS 303 V G + +ASG D VR+WD S F GH V++ L G+ ++S Sbjct: 147 VISALCFGKHQNTWVLASGADDSRVRLWDLNSSRSMAVFEGHSSVIRGLTFEPTGSFLLS 206 Query: 302 VSTDKSARVFDI 267 S DK+ +V++I Sbjct: 207 GSRDKTVQVWNI 218 Score = 58.2 bits (139), Expect = 2e-08 Identities = 33/126 (26%), Positives = 59/126 (46%), Gaps = 1/126 (0%) Frame = -2 Query: 638 SGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCE-HDEGVTCL 462 S + V ++ H + I +S +A+ S D+T+ +WD + + H GV Sbjct: 454 SNRAVWTIKAHDRDVNAIQVSKDGRIIASASQDKTIKLWDSSTGEVVGVLRGHRRGVWAC 513 Query: 461 AWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSA 282 ++ SR +ASG D +RIW+ + +T GH + L + G +VS + D Sbjct: 514 SFNPFSRQLASGSGDRTIRIWNVDTQQCVQTLEGHTGAILKLIYISQGTQVVSAAADGLV 573 Query: 281 RVFDIS 264 +V+ +S Sbjct: 574 KVWSLS 579 Score = 52.4 bits (124), Expect = 1e-06 Identities = 41/150 (27%), Positives = 67/150 (44%), Gaps = 18/150 (12%) Frame = -2 Query: 659 VHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDL-----ARQAIRS 495 + ++S + QV G L GHT+ + + S W+ATG+ D T+ +W+L + I Sbjct: 346 IDVISTDGTQVFGVLEGHTDIVLTLDSSEDGVWLATGAKDNTVRLWNLNIEDNVYKCIHV 405 Query: 494 TCEHDEGVTCLAW-----LGSSRYVASGCIDGMVRIWD--------SLSGDLARTFSGHR 354 H VT +A G ++AS D ++ ++ S T H Sbjct: 406 FTGHTASVTAVALGPLDVNGYPTFLASSSQDRTLKRFNLGSQLNKSDFSNRAVWTIKAHD 465 Query: 353 DVVQSLAVSADGNSIVSVSTDKSARVFDIS 264 V ++ VS DG I S S DK+ +++D S Sbjct: 466 RDVNAIQVSKDGRIIASASQDKTIKLWDSS 495 Score = 50.1 bits (118), Expect = 6e-06 Identities = 32/129 (24%), Positives = 61/129 (47%), Gaps = 14/129 (10%) Frame = -2 Query: 611 GHTNSIECIG-----ISSRYNWVATGSIDRTLIIWDLARQ---------AIRSTCEHDEG 474 GHT S+ + ++ ++A+ S DRTL ++L Q A+ + HD Sbjct: 408 GHTASVTAVALGPLDVNGYPTFLASSSQDRTLKRFNLGSQLNKSDFSNRAVWTIKAHDRD 467 Query: 473 VTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVST 294 V + R +AS D +++WDS +G++ GHR V + + + + S S Sbjct: 468 VNAIQVSKDGRIIASASQDKTIKLWDSSTGEVVGVLRGHRRGVWACSFNPFSRQLASGSG 527 Query: 293 DKSARVFDI 267 D++ R++++ Sbjct: 528 DRTIRIWNV 536 Score = 37.7 bits (86), Expect = 0.031 Identities = 22/93 (23%), Positives = 47/93 (50%), Gaps = 1/93 (1%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLAR-QAIRSTCE 486 ++ I ++++ Q V +L GHT +I + S+ V + + D + +W L+ + + + Sbjct: 530 TIRIWNVDTQQCVQTLEGHTGAILKLIYISQGTQVVSAAADGLVKVWSLSSGECVATLDN 589 Query: 485 HDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLS 387 H++ V LA + SG D +V +W ++ Sbjct: 590 HEDRVWALASRFDGSLLVSGGADAVVSVWKDVT 622 Score = 36.6 bits (83), Expect = 0.069 Identities = 27/133 (20%), Positives = 61/133 (45%), Gaps = 8/133 (6%) Frame = -2 Query: 659 VHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCEHD 480 V + +NS + + GH++ I + +++ +GS D+T+ +W++ +++ T Sbjct: 171 VRLWDLNSSRSMAVFEGHSSVIRGLTFEPTGSFLLSGSRDKTVQVWNIKKRSAVRTIPVF 230 Query: 479 EGVTCLAWLG---SSRYVASGCIDGMVRIWDSLSGD-----LARTFSGHRDVVQSLAVSA 324 V + W+ + + + ++ WD SG + T S ++Q + S Sbjct: 231 HSVEAIGWVNGQPEEKILYTAGEGNLILAWDWKSGSRLDPGVDTTHSETNAIIQVVPFSE 290 Query: 323 DGNSIVSVSTDKS 285 N+++SV +D S Sbjct: 291 --NTLLSVHSDLS 301 Score = 29.6 bits (65), Expect = 8.4 Identities = 20/77 (25%), Positives = 38/77 (49%), Gaps = 3/77 (3%) Frame = -2 Query: 482 DEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFS---GHRDVVQSLAVSADGNS 312 DE + C AW+G + + D +S D + F GH D+V +L S DG Sbjct: 324 DEVIDC-AWIGDDHLAVCSNTEFI----DVISTDGTQVFGVLEGHTDIVLTLDSSEDGVW 378 Query: 311 IVSVSTDKSARVFDISM 261 + + + D + R++++++ Sbjct: 379 LATGAKDNTVRLWNLNI 395
>WDR71_HUMAN (Q9BRP4) WD-repeat protein 71 (Protein G-16)| Length = 392 Score = 69.7 bits (169), Expect = 7e-12 Identities = 39/114 (34%), Positives = 57/114 (50%), Gaps = 1/114 (0%) Frame = -2 Query: 608 HTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCE-HDEGVTCLAWLGSSRYVA 432 HT SI C+ ISSR + S D T+ IW + +R E H V C + S V Sbjct: 91 HTKSITCLDISSRGGLGVSSSTDGTMKIWQASNGELRRVLEGHVFDVNCCRFFPSGLVVL 150 Query: 431 SGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFD 270 SG +D ++IW + TF GH+ + A+ G ++VS S D +AR++D Sbjct: 151 SGGMDAQLKIWSAEDASCVVTFKGHKGGILDTAIVDRGRNVVSASRDGTARLWD 204
>PK1IP_BOVIN (Q5EA99) p21-activated protein kinase-interacting protein 1| (PAK1-interacting protein 1) Length = 392 Score = 69.7 bits (169), Expect = 7e-12 Identities = 36/115 (31%), Positives = 66/115 (57%), Gaps = 1/115 (0%) Frame = -2 Query: 608 HTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCEHDEG-VTCLAWLGSSRYVA 432 HT S+ + ++SR+ V TGS D T+ I+D+ ++ H G +TCL + G+ R++ Sbjct: 41 HTASLSAVAVNSRF--VVTGSKDETIHIYDMKKKVDHGALMHHNGTITCLKFHGN-RHLI 97 Query: 431 SGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFDI 267 SG DG++ +WD+ + ++ H+ V L++ G +SV TDK+ R +++ Sbjct: 98 SGAEDGLICVWDARRWECLKSIRAHKGHVTFLSIHPSGRLALSVGTDKTLRTWNL 152
>LIS1_MACFA (Q8HXX0) Platelet-activating factor acetylhydrolase IB alpha| subunit (PAF acetylhydrolase 45 kDa subunit) (PAF-AH 45 kDa subunit) (PAF-AH alpha) (PAFAH alpha) (Lissencephaly-1 protein) (LIS-1) Length = 409 Score = 69.3 bits (168), Expect = 1e-11 Identities = 36/134 (26%), Positives = 72/134 (53%), Gaps = 1/134 (0%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLAR-QAIRSTCE 486 ++ + +G +L GHT+S++ I + + S D T+ +WD + IR+ Sbjct: 130 TIKVWDYETGDFERTLKGHTDSVQDISFDHSGKLLTSCSADMTIKLWDFQGFECIRTMHG 189 Query: 485 HDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIV 306 HD V+ +A + + ++ S D +++W+ +G +TF+GHR+ V+ + + DG I Sbjct: 190 HDHNVSSVAIMPNGDHLVSASRDKTIKMWEVQTGYCVKTFTGHREWVRMVRPNQDGTLIA 249 Query: 305 SVSTDKSARVFDIS 264 S S D++ RV+ ++ Sbjct: 250 SCSNDQTVRVWVVA 263 Score = 55.8 bits (133), Expect = 1e-07 Identities = 35/152 (23%), Positives = 69/152 (45%), Gaps = 21/152 (13%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTC-E 486 ++ + + +G V + GH + + + +A+ S D+T+ +W +A + ++ E Sbjct: 214 TIKMWEVQTGYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVWVVATKECKAELRE 273 Query: 485 HDEGVTCLAWLGSSRY--------------------VASGCIDGMVRIWDSLSGDLARTF 366 H+ V C++W S Y + SG D +++WD +G T Sbjct: 274 HEHVVECISWAPESSYSSISEATGSETKKSGKPGPFLLSGSRDKTIKMWDVSTGMCLMTL 333 Query: 365 SGHRDVVQSLAVSADGNSIVSVSTDKSARVFD 270 GH + V+ + + G I+S + DK+ RV+D Sbjct: 334 VGHDNWVRGVLFHSGGKFILSCADDKTLRVWD 365 Score = 54.3 bits (129), Expect = 3e-07 Identities = 29/119 (24%), Positives = 61/119 (51%), Gaps = 1/119 (0%) Frame = -2 Query: 620 SLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCE-HDEGVTCLAWLGSS 444 +L GH + + + ++ + + S D T+ +WD T + H + V +++ S Sbjct: 102 ALSGHRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLKGHTDSVQDISFDHSG 161 Query: 443 RYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFDI 267 + + S D +++WD + RT GH V S+A+ +G+ +VS S DK+ +++++ Sbjct: 162 KLLTSCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHLVSASRDKTIKMWEV 220 Score = 47.0 bits (110), Expect = 5e-05 Identities = 22/90 (24%), Positives = 52/90 (57%), Gaps = 1/90 (1%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLA-RQAIRSTCE 486 ++ + +++G + +LVGH N + + S ++ + + D+TL +WD ++ +++ Sbjct: 318 TIKMWDVSTGMCLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDYKNKRCMKTLNA 377 Query: 485 HDEGVTCLAWLGSSRYVASGCIDGMVRIWD 396 H+ VT L + ++ YV +G +D V++W+ Sbjct: 378 HEHFVTSLDFHKTAPYVVTGSVDQTVKVWE 407 Score = 45.4 bits (106), Expect = 1e-04 Identities = 19/61 (31%), Positives = 32/61 (52%) Frame = -2 Query: 437 VASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFDISMF 258 + S D +++WD +GD RT GH D VQ ++ G + S S D + +++D F Sbjct: 122 MVSASEDATIKVWDYETGDFERTLKGHTDSVQDISFDHSGKLLTSCSADMTIKLWDFQGF 181 Query: 257 K 255 + Sbjct: 182 E 182 Score = 43.9 bits (102), Expect = 4e-04 Identities = 23/99 (23%), Positives = 50/99 (50%), Gaps = 1/99 (1%) Frame = -2 Query: 563 WVATGSIDRTLIIWDLAR-QAIRSTCEHDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLS 387 ++ +GS D+T+ +WD++ + + HD V + + +++ S D +R+WD + Sbjct: 309 FLLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDYKN 368 Query: 386 GDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFD 270 +T + H V SL +V+ S D++ +V++ Sbjct: 369 KRCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVKVWE 407
>KTNB1_HUMAN (Q9BVA0) Katanin p80 WD40-containing subunit B1 (Katanin p80| subunit B1) (p80 katanin) Length = 655 Score = 68.9 bits (167), Expect = 1e-11 Identities = 37/136 (27%), Positives = 69/136 (50%), Gaps = 1/136 (0%) Frame = -2 Query: 659 VHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDL-ARQAIRSTCEH 483 V++ SIN + SL GHT+ +E + +++ + GS ++ +WDL A + +R+ H Sbjct: 45 VNLWSINKPNCIMSLTGHTSPVESVRLNTPEELIVAGSQSGSIRVWDLEAAKILRTLMGH 104 Query: 482 DEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVS 303 + L + +VASG D +++WD + GH V+ L S DG + S Sbjct: 105 KANICSLDFHPYGEFVASGSQDTNIKLWDIRRKGCVFRYRGHSQAVRCLRFSPDGKWLAS 164 Query: 302 VSTDKSARVFDISMFK 255 + D + +++D++ K Sbjct: 165 AADDHTVKLWDLTAGK 180 Score = 65.1 bits (157), Expect = 2e-10 Identities = 34/137 (24%), Positives = 70/137 (51%), Gaps = 1/137 (0%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQA-IRSTCE 486 S+ + + + +++ +L+GH +I + +VA+GS D + +WD+ R+ + Sbjct: 86 SIRVWDLEAAKILRTLMGHKANICSLDFHPYGEFVASGSQDTNIKLWDIRRKGCVFRYRG 145 Query: 485 HDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIV 306 H + V CL + +++AS D V++WD +G + F GH V + + + Sbjct: 146 HSQAVRCLRFSPDGKWLASAADDHTVKLWDLTAGKMMSEFPGHTGPVNVVEFHPNEYLLA 205 Query: 305 SVSTDKSARVFDISMFK 255 S S+D++ R +D+ F+ Sbjct: 206 SGSSDRTIRFWDLEKFQ 222 Score = 48.5 bits (114), Expect = 2e-05 Identities = 31/114 (27%), Positives = 51/114 (44%), Gaps = 1/114 (0%) Frame = -2 Query: 611 GHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCEHDEGVTCLAWLGSSRYV- 435 GH+ ++ C+ S W+A+ + D T+ +WDL + S G + + Y+ Sbjct: 145 GHSQAVRCLRFSPDGKWLASAADDHTVKLWDLTAGKMMSEFPGHTGPVNVVEFHPNEYLL 204 Query: 434 ASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVF 273 ASG D +R WD + G V+S+ + DG + S D S RV+ Sbjct: 205 ASGSSDRTIRFWDLEKFQVVSCIEGEPGPVRSVLFNPDGCCLYSGCQD-SLRVY 257 Score = 44.7 bits (104), Expect = 3e-04 Identities = 28/119 (23%), Positives = 53/119 (44%), Gaps = 2/119 (1%) Frame = -2 Query: 617 LVGHTNSIECIGISSRYN-WVATGSIDRTLIIWDLAR-QAIRSTCEHDEGVTCLAWLGSS 444 +V H +++ + + +ATG D + +W + + I S H V + Sbjct: 16 IVAHASNVSSLVLGKASGRLLATGGDDCRVNLWSINKPNCIMSLTGHTSPVESVRLNTPE 75 Query: 443 RYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFDI 267 + +G G +R+WD + + RT GH+ + SL G + S S D + +++DI Sbjct: 76 ELIVAGSQSGSIRVWDLEAAKILRTLMGHKANICSLDFHPYGEFVASGSQDTNIKLWDI 134 Score = 38.9 bits (89), Expect = 0.014 Identities = 22/85 (25%), Positives = 41/85 (48%), Gaps = 1/85 (1%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCEH 483 +V + + +G+++ GHT + + +A+GS DRT+ WDL + + S E Sbjct: 170 TVKLWDLTAGKMMSEFPGHTGPVNVVEFHPNEYLLASGSSDRTIRFWDLEKFQVVSCIEG 229 Query: 482 DEG-VTCLAWLGSSRYVASGCIDGM 411 + G V + + + SGC D + Sbjct: 230 EPGPVRSVLFNPDGCCLYSGCQDSL 254 Score = 33.1 bits (74), Expect = 0.76 Identities = 19/65 (29%), Positives = 32/65 (49%) Frame = -2 Query: 449 SSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFD 270 S R +A+G D V +W + + +GH V+S+ ++ IV+ S S RV+D Sbjct: 32 SGRLLATGGDDCRVNLWSINKPNCIMSLTGHTSPVESVRLNTPEELIVAGSQSGSIRVWD 91 Query: 269 ISMFK 255 + K Sbjct: 92 LEAAK 96
>TAF5_SCHPO (O13282) Transcription initiation factor TFIID subunit 5| (Transcription initiation factor TFIID 72 kDa subunit) (TAFII-72) Length = 643 Score = 68.9 bits (167), Expect = 1e-11 Identities = 35/116 (30%), Positives = 62/116 (53%), Gaps = 1/116 (0%) Frame = -2 Query: 611 GHTNSIECIGISSRYNWVATGSIDRTLIIWDLAR-QAIRSTCEHDEGVTCLAWLGSSRYV 435 GH + ++C+ +V TGS D+T +WD+ R ++R H + VT +A + Sbjct: 461 GHLSDVDCVTFHPNSAYVLTGSSDKTCRLWDVHRGHSVRVFNGHTQPVTAVAIAPDGHTM 520 Query: 434 ASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFDI 267 AS +G++ +WD +G +T GHR + SL+ S + +VS +D + R +D+ Sbjct: 521 ASADSEGLIHLWDIGTGRRIKTMRGHRGNIYSLSFSRESTVLVSGGSDCTVRAWDV 576 Score = 62.4 bits (150), Expect = 1e-09 Identities = 35/133 (26%), Positives = 65/133 (48%), Gaps = 1/133 (0%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLAR-QAIRSTCE 486 S + S+++ + + GHT + + ++ AT S D+T +W +R Sbjct: 402 SARLWSVDTKTALVAYKGHTGPVWDVAFGPFGHYFATASHDQTAQLWSCDHIYPLRVFAG 461 Query: 485 HDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIV 306 H V C+ + +S YV +G D R+WD G R F+GH V ++A++ DG+++ Sbjct: 462 HLSDVDCVTFHPNSAYVLTGSSDKTCRLWDVHRGHSVRVFNGHTQPVTAVAIAPDGHTMA 521 Query: 305 SVSTDKSARVFDI 267 S ++ ++DI Sbjct: 522 SADSEGLIHLWDI 534
>KTNB1_MOUSE (Q8BG40) Katanin p80 WD40-containing subunit B1 (Katanin p80| subunit B1) (p80 katanin) Length = 658 Score = 68.9 bits (167), Expect = 1e-11 Identities = 37/136 (27%), Positives = 69/136 (50%), Gaps = 1/136 (0%) Frame = -2 Query: 659 VHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDL-ARQAIRSTCEH 483 V++ SIN + SL GHT+ +E + +++ + GS ++ +WDL A + +R+ H Sbjct: 45 VNLWSINKPNCIMSLTGHTSPVESVRLNTPEELIVAGSQSGSIRVWDLEAAKILRTLMGH 104 Query: 482 DEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVS 303 + L + +VASG D +++WD + GH V+ L S DG + S Sbjct: 105 KANICSLDFHPYGEFVASGSQDTNIKLWDIRRKGCVFRYRGHSQAVRCLRFSPDGKWLAS 164 Query: 302 VSTDKSARVFDISMFK 255 + D + +++D++ K Sbjct: 165 AADDHTVKLWDLTAGK 180 Score = 65.1 bits (157), Expect = 2e-10 Identities = 34/137 (24%), Positives = 70/137 (51%), Gaps = 1/137 (0%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQA-IRSTCE 486 S+ + + + +++ +L+GH +I + +VA+GS D + +WD+ R+ + Sbjct: 86 SIRVWDLEAAKILRTLMGHKANICSLDFHPYGEFVASGSQDTNIKLWDIRRKGCVFRYRG 145 Query: 485 HDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIV 306 H + V CL + +++AS D V++WD +G + F GH V + + + Sbjct: 146 HSQAVRCLRFSPDGKWLASAADDHTVKLWDLTAGKMMSEFPGHTGPVNVVEFHPNEYLLA 205 Query: 305 SVSTDKSARVFDISMFK 255 S S+D++ R +D+ F+ Sbjct: 206 SGSSDRTIRFWDLEKFQ 222 Score = 48.5 bits (114), Expect = 2e-05 Identities = 31/114 (27%), Positives = 51/114 (44%), Gaps = 1/114 (0%) Frame = -2 Query: 611 GHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCEHDEGVTCLAWLGSSRYV- 435 GH+ ++ C+ S W+A+ + D T+ +WDL + S G + + Y+ Sbjct: 145 GHSQAVRCLRFSPDGKWLASAADDHTVKLWDLTAGKMMSEFPGHTGPVNVVEFHPNEYLL 204 Query: 434 ASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVF 273 ASG D +R WD + G V+S+ + DG + S D S RV+ Sbjct: 205 ASGSSDRTIRFWDLEKFQVVSCIEGEPGPVRSVLFNPDGCCLYSGCQD-SLRVY 257 Score = 44.7 bits (104), Expect = 3e-04 Identities = 28/119 (23%), Positives = 53/119 (44%), Gaps = 2/119 (1%) Frame = -2 Query: 617 LVGHTNSIECIGISSRYN-WVATGSIDRTLIIWDLAR-QAIRSTCEHDEGVTCLAWLGSS 444 +V H +++ + + +ATG D + +W + + I S H V + Sbjct: 16 IVAHASNVSSLVLGKASGRLLATGGDDCRVNLWSINKPNCIMSLTGHTSPVESVRLNTPE 75 Query: 443 RYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFDI 267 + +G G +R+WD + + RT GH+ + SL G + S S D + +++DI Sbjct: 76 ELIVAGSQSGSIRVWDLEAAKILRTLMGHKANICSLDFHPYGEFVASGSQDTNIKLWDI 134 Score = 38.9 bits (89), Expect = 0.014 Identities = 22/85 (25%), Positives = 41/85 (48%), Gaps = 1/85 (1%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCEH 483 +V + + +G+++ GHT + + +A+GS DRT+ WDL + + S E Sbjct: 170 TVKLWDLTAGKMMSEFPGHTGPVNVVEFHPNEYLLASGSSDRTIRFWDLEKFQVVSCIEG 229 Query: 482 DEG-VTCLAWLGSSRYVASGCIDGM 411 + G V + + + SGC D + Sbjct: 230 EPGPVRSVLFNPDGCCLYSGCQDSL 254 Score = 33.1 bits (74), Expect = 0.76 Identities = 19/65 (29%), Positives = 32/65 (49%) Frame = -2 Query: 449 SSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFD 270 S R +A+G D V +W + + +GH V+S+ ++ IV+ S S RV+D Sbjct: 32 SGRLLATGGDDCRVNLWSINKPNCIMSLTGHTSPVESVRLNTPEELIVAGSQSGSIRVWD 91 Query: 269 ISMFK 255 + K Sbjct: 92 LEAAK 96
>KTNB1_ARATH (Q8H0T9) Katanin p80 WD40-containing subunit B1 homolog 1| Length = 837 Score = 68.6 bits (166), Expect = 2e-11 Identities = 36/137 (26%), Positives = 68/137 (49%), Gaps = 1/137 (0%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCE- 486 ++ + + ++V +L GH ++ + + A+GS+D L IWD+ ++ T + Sbjct: 82 TIKLWDLEEAKIVRTLTGHRSNCISVDFHPFGEFFASGSLDTNLKIWDIRKKGCIHTYKG 141 Query: 485 HDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIV 306 H GV L + R+V SG D +V++WD +G L F H +QSL + Sbjct: 142 HTRGVNVLRFTPDGRWVVSGGEDNIVKVWDLTAGKLLTEFKSHEGQIQSLDFHPHEFLLA 201 Query: 305 SVSTDKSARVFDISMFK 255 + S D++ + +D+ F+ Sbjct: 202 TGSADRTVKFWDLETFE 218 Score = 60.8 bits (146), Expect = 3e-09 Identities = 36/136 (26%), Positives = 64/136 (47%), Gaps = 1/136 (0%) Frame = -2 Query: 659 VHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLAR-QAIRSTCEH 483 V++ +I + SL GH++ I+ + + VA G+ T+ +WDL + +R+ H Sbjct: 41 VNLWAIGKPNAILSLYGHSSGIDSVTFDASEVLVAAGAASGTIKLWDLEEAKIVRTLTGH 100 Query: 482 DEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVS 303 + + + ASG +D ++IWD T+ GH V L + DG +VS Sbjct: 101 RSNCISVDFHPFGEFFASGSLDTNLKIWDIRKKGCIHTYKGHTRGVNVLRFTPDGRWVVS 160 Query: 302 VSTDKSARVFDISMFK 255 D +V+D++ K Sbjct: 161 GGEDNIVKVWDLTAGK 176 Score = 57.4 bits (137), Expect = 4e-08 Identities = 33/118 (27%), Positives = 57/118 (48%), Gaps = 2/118 (1%) Frame = -2 Query: 614 VGHTNSIECIGISSRYNWV-ATGSIDRTLIIWDLAR-QAIRSTCEHDEGVTCLAWLGSSR 441 V H+ ++ C+ I + + V TG D + +W + + AI S H G+ + + S Sbjct: 13 VAHSAAVNCLKIGRKSSRVLVTGGEDHKVNLWAIGKPNAILSLYGHSSGIDSVTFDASEV 72 Query: 440 YVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFDI 267 VA+G G +++WD + RT +GHR S+ G S S D + +++DI Sbjct: 73 LVAAGAASGTIKLWDLEEAKIVRTLTGHRSNCISVDFHPFGEFFASGSLDTNLKIWDI 130 Score = 41.6 bits (96), Expect = 0.002 Identities = 26/114 (22%), Positives = 52/114 (45%), Gaps = 1/114 (0%) Frame = -2 Query: 611 GHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCEHDEG-VTCLAWLGSSRYV 435 GHT + + + WV +G D + +WDL + + + EG + L + + Sbjct: 141 GHTRGVNVLRFTPDGRWVVSGGEDNIVKVWDLTAGKLLTEFKSHEGQIQSLDFHPHEFLL 200 Query: 434 ASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVF 273 A+G D V+ WD + +L + V+ L+ + DG +++ +S ++F Sbjct: 201 ATGSADRTVKFWDLETFELIGSGGPETAGVRCLSFNPDGKTVL-CGLQESLKIF 253
>YH92_CAEEL (Q23256) Hypothetical WD-repeat protein ZC302.2| Length = 501 Score = 68.6 bits (166), Expect = 2e-11 Identities = 35/121 (28%), Positives = 64/121 (52%), Gaps = 1/121 (0%) Frame = -2 Query: 629 VVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQA-IRSTCEHDEGVTCLAWL 453 +V ++ GHT S+ I S ++ TGS D+ + +W+ +++ H G+ +W Sbjct: 205 LVKTISGHTKSVSVIKFSYCGKYLGTGSADKQIKVWNTVDMTYLQTLASHQLGINDFSWS 264 Query: 452 GSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVF 273 +S+++AS D V+I+D +SG RT GH + V + + + I S D++ RV+ Sbjct: 265 SNSQFIASASDDTTVKIFDVISGACLRTMRGHTNYVFCCSFNPQSSLIASAGFDETVRVW 324 Query: 272 D 270 D Sbjct: 325 D 325 Score = 62.4 bits (150), Expect = 1e-09 Identities = 33/134 (24%), Positives = 67/134 (50%), Gaps = 3/134 (2%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDL-ARQAIRSTCE 486 +V I + SG + ++ GHTN + C + + + +A+ D T+ +WD ++ Sbjct: 278 TVKIFDVISGACLRTMRGHTNYVFCCSFNPQSSLIASAGFDETVRVWDFKTGLCVKCIPA 337 Query: 485 HDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTF--SGHRDVVQSLAVSADGNS 312 H + +T +++ +A+ DG +R+WD+ SG +T + H V + S +G Sbjct: 338 HSDPITSISYNHDGNTMATSSYDGCIRVWDAASGSCLKTLVDTDHAPVT-FVCFSPNGKY 396 Query: 311 IVSVSTDKSARVFD 270 ++S D S +++D Sbjct: 397 LLSAQLDSSLKLWD 410 Score = 58.9 bits (141), Expect = 1e-08 Identities = 36/118 (30%), Positives = 59/118 (50%), Gaps = 1/118 (0%) Frame = -2 Query: 620 SLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQA-IRSTCEHDEGVTCLAWLGSS 444 +L H I SS ++A+ S D T+ I+D+ A +R+ H V C ++ S Sbjct: 250 TLASHQLGINDFSWSSNSQFIASASDDTTVKIFDVISGACLRTMRGHTNYVFCCSFNPQS 309 Query: 443 RYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFD 270 +AS D VR+WD +G + H D + S++ + DGN++ + S D RV+D Sbjct: 310 SLIASAGFDETVRVWDFKTGLCVKCIPAHSDPITSISYNHDGNTMATSSYDGCIRVWD 367 Score = 47.0 bits (110), Expect = 5e-05 Identities = 32/137 (23%), Positives = 63/137 (45%), Gaps = 5/137 (3%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLAR-QAIRSTCE 486 +V + +G V + H++ I I + N +AT S D + +WD A +++ + Sbjct: 320 TVRVWDFKTGLCVKCIPAHSDPITSISYNHDGNTMATSSYDGCIRVWDAASGSCLKTLVD 379 Query: 485 HDEG-VTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSAD---G 318 D VT + + + +Y+ S +D +++WD + ++GH++ L + G Sbjct: 380 TDHAPVTFVCFSPNGKYLLSAQLDSSLKLWDPKKAKPLKYYNGHKNKKYCLFANMSVPLG 439 Query: 317 NSIVSVSTDKSARVFDI 267 I+S S D V+ I Sbjct: 440 KHIISGSEDGRILVWSI 456
>PK1IP_MOUSE (Q9DCE5) p21-activated protein kinase-interacting protein 1| (PAK1-interacting protein 1) (Putative PAK inhibitor Skb15) Length = 382 Score = 68.6 bits (166), Expect = 2e-11 Identities = 41/115 (35%), Positives = 63/115 (54%), Gaps = 1/115 (0%) Frame = -2 Query: 608 HTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCEHDEG-VTCLAWLGSSRYVA 432 HT S+ + +SRY V +GS D T+ I+D+ R+ H G VTCL + G+ +++ Sbjct: 41 HTASLSVLASNSRY--VVSGSKDETIHIYDMKRKVEHGALVHHAGTVTCLKFHGN-QHLI 97 Query: 431 SGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFDI 267 SG DG + IWD +TF HR V L++ G +SV TDK+ R +++ Sbjct: 98 SGAEDGHICIWDVKRWKCLKTFKAHRGHVTFLSIHPSGKLALSVGTDKTLRTWNL 152
>NLE1_MOUSE (Q8VEJ4) Notchless homolog 1| Length = 484 Score = 68.2 bits (165), Expect = 2e-11 Identities = 39/132 (29%), Positives = 70/132 (53%), Gaps = 7/132 (5%) Frame = -2 Query: 620 SLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCE-HDEGVTCLAWLGSS 444 SL GH+ ++ + S ++A+GS D T+ WDL+ + TC+ H V ++W Sbjct: 108 SLEGHSEAVISVAFSPTGKYLASGSGDTTVRFWDLSTETPHFTCKGHRHWVLSISWSPDG 167 Query: 443 RYVASGCIDGMVRIWDSLSG-DLARTFSGHRDVVQSLA-----VSADGNSIVSVSTDKSA 282 + +ASGC +G + +WD +G + RT +GH + L+ ++ + + S S D S Sbjct: 168 KKLASGCKNGQILLWDPSTGLQVGRTLTGHSKWITGLSWEPLHMNPECRYVASSSKDGSV 227 Query: 281 RVFDISMFK*EK 246 RV+D + + E+ Sbjct: 228 RVWDTTAGRCER 239 Score = 59.3 bits (142), Expect = 1e-08 Identities = 35/116 (30%), Positives = 55/116 (47%), Gaps = 1/116 (0%) Frame = -2 Query: 617 LVGHTNSIECIGISSRYNWVATGSIDRTLIIWD-LARQAIRSTCEHDEGVTCLAWLGSSR 441 + GH I + S VA+ S D+++ +WD + + S H V +AW SR Sbjct: 367 MTGHQALINQVLFSPDSRIVASASFDKSIKLWDGRTGKYLASLRGHVAAVYQIAWSADSR 426 Query: 440 YVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVF 273 + SG D +++WD + LA GH D V ++ S DG + S DK R++ Sbjct: 427 LLVSGSSDSTLKVWDVKAQKLATDLPGHADEVYAVDWSPDGQRVASGGKDKCLRIW 482 Score = 57.4 bits (137), Expect = 4e-08 Identities = 37/118 (31%), Positives = 57/118 (48%), Gaps = 10/118 (8%) Frame = -2 Query: 578 SSRYNWV--------ATGSIDRTLIIWDLA--RQAIRSTCEHDEGVTCLAWLGSSRYVAS 429 SSRYN V +GS D TL +W A ++ + H + + + SR VAS Sbjct: 329 SSRYNLVRGQGPERLVSGSDDFTLFLWSPAEDKKPLARMTGHQALINQVLFSPDSRIVAS 388 Query: 428 GCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFDISMFK 255 D +++WD +G + GH V +A SAD +VS S+D + +V+D+ K Sbjct: 389 ASFDKSIKLWDGRTGKYLASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDVKAQK 446 Score = 53.5 bits (127), Expect = 5e-07 Identities = 35/110 (31%), Positives = 55/110 (50%), Gaps = 6/110 (5%) Frame = -2 Query: 632 QVVGSLVGHTNSI-----ECIGISSRYNWVATGSIDRTLIIWDL-ARQAIRSTCEHDEGV 471 QV +L GH+ I E + ++ +VA+ S D ++ +WD A + R H + V Sbjct: 189 QVGRTLTGHSKWITGLSWEPLHMNPECRYVASSSKDGSVRVWDTTAGRCERILTGHTQSV 248 Query: 470 TCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSAD 321 TCL W G + S D +++W + G L RT GH V ++A+S D Sbjct: 249 TCLRW-GGDGLLYSASQDRTIKVWRAHDGVLCRTLQGHGHWVNTMALSTD 297 Score = 45.1 bits (105), Expect = 2e-04 Identities = 27/89 (30%), Positives = 45/89 (50%), Gaps = 1/89 (1%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCE- 486 S+ + +G+ + SL GH ++ I S+ + +GS D TL +WD+ Q + + Sbjct: 394 SIKLWDGRTGKYLASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDVKAQKLATDLPG 453 Query: 485 HDEGVTCLAWLGSSRYVASGCIDGMVRIW 399 H + V + W + VASG D +RIW Sbjct: 454 HADEVYAVDWSPDGQRVASGGKDKCLRIW 482
>YZLL_CAEEL (Q93847) Hypothetical WD-repeat protein K04G11.4| Length = 395 Score = 68.2 bits (165), Expect = 2e-11 Identities = 41/133 (30%), Positives = 71/133 (53%), Gaps = 3/133 (2%) Frame = -2 Query: 659 VHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLAR--QAIRSTCE 486 V + ++SG+ V +L GHTN + C + +A+GS D T+ IW AR I S Sbjct: 172 VKVFDVSSGRCVKTLKGHTNYVFCCCFNPSGTLIASGSFDETIRIW-CARNGNTIFSIPG 230 Query: 485 HDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLART-FSGHRDVVQSLAVSADGNSI 309 H++ V+ + + Y+ASG DG+VRIWDS +G +T + + S +G I Sbjct: 231 HEDPVSSVCFNRDGAYLASGSYDGIVRIWDSTTGTCVKTLIDEEHPPITHVKFSPNGKYI 290 Query: 308 VSVSTDKSARVFD 270 ++ + + + +++D Sbjct: 291 LASNLNNTLKLWD 303 Score = 55.1 bits (131), Expect = 2e-07 Identities = 33/118 (27%), Positives = 59/118 (50%), Gaps = 1/118 (0%) Frame = -2 Query: 620 SLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLAR-QAIRSTCEHDEGVTCLAWLGSS 444 +L+GH I SS + + S D+ + ++D++ + +++ H V C + S Sbjct: 143 TLMGHRLGINEFSWSSDSKLIVSCSDDKLVKVFDVSSGRCVKTLKGHTNYVFCCCFNPSG 202 Query: 443 RYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFD 270 +ASG D +RIW + +G+ + GH D V S+ + DG + S S D R++D Sbjct: 203 TLIASGSFDETIRIWCARNGNTIFSIPGHEDPVSSVCFNRDGAYLASGSYDGIVRIWD 260 Score = 52.0 bits (123), Expect = 2e-06 Identities = 30/112 (26%), Positives = 53/112 (47%) Frame = -2 Query: 608 HTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCEHDEGVTCLAWLGSSRYVAS 429 H SI I S ++ +GS D ++ IW + ++ H G+ +W S+ + S Sbjct: 106 HKKSISGIKFSPDGRYMGSGSADCSIKIWRMDFVYEKTLMGHRLGINEFSWSSDSKLIVS 165 Query: 428 GCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVF 273 D +V+++D SG +T GH + V + G I S S D++ R++ Sbjct: 166 CSDDKLVKVFDVSSGRCVKTLKGHTNYVFCCCFNPSGTLIASGSFDETIRIW 217 Score = 46.2 bits (108), Expect = 9e-05 Identities = 25/88 (28%), Positives = 42/88 (47%) Frame = -2 Query: 527 IWDLARQAIRSTCEHDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDV 348 +W + H + ++ + + RY+ SG D ++IW + +T GHR Sbjct: 92 LWPTYKLVAEIPNAHKKSISGIKFSPDGRYMGSGSADCSIKIW-RMDFVYEKTLMGHRLG 150 Query: 347 VQSLAVSADGNSIVSVSTDKSARVFDIS 264 + + S+D IVS S DK +VFD+S Sbjct: 151 INEFSWSSDSKLIVSCSDDKLVKVFDVS 178 Score = 43.1 bits (100), Expect = 7e-04 Identities = 27/137 (19%), Positives = 63/137 (45%), Gaps = 5/137 (3%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTC-- 489 ++ I +G + S+ GH + + + + ++A+GS D + IWD T Sbjct: 213 TIRIWCARNGNTIFSIPGHEDPVSSVCFNRDGAYLASGSYDGIVRIWDSTTGTCVKTLID 272 Query: 488 EHDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVS---ADG 318 E +T + + + +Y+ + ++ +++WD + + ++GH + +A + G Sbjct: 273 EEHPPITHVKFSPNGKYILASNLNNTLKLWDYQKLRVLKEYTGHENSKYCVAANFSVTGG 332 Query: 317 NSIVSVSTDKSARVFDI 267 IVS S D ++++ Sbjct: 333 KWIVSGSEDHKVYIWNL 349 Score = 40.4 bits (93), Expect = 0.005 Identities = 28/133 (21%), Positives = 57/133 (42%), Gaps = 5/133 (3%) Frame = -2 Query: 659 VHIVSINSGQVVGSLVGHTNS-IECIGISSRYNWVATGSIDRTLIIWDLAR-QAIRSTCE 486 V I +G V +L+ + I + S ++ +++ TL +WD + + ++ Sbjct: 256 VRIWDSTTGTCVKTLIDEEHPPITHVKFSPNGKYILASNLNNTLKLWDYQKLRVLKEYTG 315 Query: 485 HDEGVTCLAW---LGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGN 315 H+ C+A + +++ SG D V IW+ + ++ +T GH V N Sbjct: 316 HENSKYCVAANFSVTGGKWIVSGSEDHKVYIWNLQTREILQTLDGHNTAVMCTDCHPGQN 375 Query: 314 SIVSVSTDKSARV 276 I S + + R+ Sbjct: 376 IIASAALEPDMRI 388
>PK1IP_BRARE (Q6TNS2) p21-activated protein kinase-interacting protein 1-like| (PAK1-interacting protein 1-like) Length = 368 Score = 67.8 bits (164), Expect = 3e-11 Identities = 35/115 (30%), Positives = 67/115 (58%), Gaps = 1/115 (0%) Frame = -2 Query: 608 HTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCEHDEG-VTCLAWLGSSRYVA 432 HT S+ + S+++ +ATGS D T+ ++D+ ++ H +G ++CL + G+S ++ Sbjct: 46 HTASLNAVSSSNQF--IATGSKDETIQLYDMCKKTEHGALLHHDGTISCLEFYGTS-HLL 102 Query: 431 SGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFDI 267 SG DG++ +W + + +T H+ V SL+V G +SV TDK+ R +++ Sbjct: 103 SGGQDGLICVWSTKKWECLKTIRAHKGQVTSLSVHPSGKLALSVGTDKTLRTWNL 157
>NLE1_PONPY (Q5RFF8) Notchless homolog 1| Length = 484 Score = 67.4 bits (163), Expect = 4e-11 Identities = 38/132 (28%), Positives = 69/132 (52%), Gaps = 7/132 (5%) Frame = -2 Query: 620 SLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCE-HDEGVTCLAWLGSS 444 SL GH+ ++ + S ++A+GS D T+ WDL+ + TC+ H V ++W Sbjct: 108 SLEGHSEAVISVAFSPTGKYLASGSGDTTVRFWDLSTETPHFTCKGHRHWVLSISWSPDG 167 Query: 443 RYVASGCIDGMVRIWDSLSG-DLARTFSGHRDVVQSLA-----VSADGNSIVSVSTDKSA 282 + +ASGC +G + +WD +G + RT +GH + L+ + + + S S D S Sbjct: 168 KKLASGCKNGQILLWDPSTGKQVGRTLAGHSKWITGLSWEPLHANPECRYVASSSKDGSV 227 Query: 281 RVFDISMFK*EK 246 R++D + + E+ Sbjct: 228 RIWDTTAGRCER 239 Score = 59.3 bits (142), Expect = 1e-08 Identities = 35/116 (30%), Positives = 55/116 (47%), Gaps = 1/116 (0%) Frame = -2 Query: 617 LVGHTNSIECIGISSRYNWVATGSIDRTLIIWD-LARQAIRSTCEHDEGVTCLAWLGSSR 441 + GH I + S VA+ S D+++ +WD + + S H V +AW SR Sbjct: 367 MTGHQALINQVLFSPDSRIVASASFDKSIKLWDGRTGKYLASLRGHVAAVYQIAWSADSR 426 Query: 440 YVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVF 273 + SG D +++WD + LA GH D V ++ S DG + S DK R++ Sbjct: 427 LLVSGSSDSTLKVWDVKAQKLAMDLPGHADEVYAVDWSPDGQRVASGGKDKCLRIW 482 Score = 57.0 bits (136), Expect = 5e-08 Identities = 38/120 (31%), Positives = 59/120 (49%), Gaps = 7/120 (5%) Frame = -2 Query: 611 GHTNSIECIGISSRYNWVATGSIDRTLIIWD--LARQAIRSTCEHDEGVTCLAWLG---- 450 GH + + I S +A+G + +++WD +Q R+ H + +T L+W Sbjct: 153 GHRHWVLSISWSPDGKKLASGCKNGQILLWDPSTGKQVGRTLAGHSKWITGLSWEPLHAN 212 Query: 449 -SSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVF 273 RYVAS DG VRIWD+ +G R +GH V L DG + S S D++ +V+ Sbjct: 213 PECRYVASSSKDGSVRIWDTTAGRCERILTGHTQSVTCLRWGGDG-LLYSASQDRTIKVW 271 Score = 54.7 bits (130), Expect = 2e-07 Identities = 35/117 (29%), Positives = 56/117 (47%), Gaps = 10/117 (8%) Frame = -2 Query: 575 SRYNWV--------ATGSIDRTLIIWDLA--RQAIRSTCEHDEGVTCLAWLGSSRYVASG 426 SRYN + +GS D TL +W A ++ + H + + + SR VAS Sbjct: 330 SRYNLMRGQGPERLVSGSDDFTLFLWSPAEDKKPLTRMTGHQALINQVLFSPDSRIVASA 389 Query: 425 CIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFDISMFK 255 D +++WD +G + GH V +A SAD +VS S+D + +V+D+ K Sbjct: 390 SFDKSIKLWDGRTGKYLASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDVKAQK 446 Score = 53.5 bits (127), Expect = 5e-07 Identities = 37/114 (32%), Positives = 58/114 (50%), Gaps = 7/114 (6%) Frame = -2 Query: 641 NSGQVVG-SLVGHTNSI-----ECIGISSRYNWVATGSIDRTLIIWDL-ARQAIRSTCEH 483 ++G+ VG +L GH+ I E + + +VA+ S D ++ IWD A + R H Sbjct: 185 STGKQVGRTLAGHSKWITGLSWEPLHANPECRYVASSSKDGSVRIWDTTAGRCERILTGH 244 Query: 482 DEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSAD 321 + VTCL W G + S D +++W + G L RT GH V ++A+S D Sbjct: 245 TQSVTCLRW-GGDGLLYSASQDRTIKVWRAHDGVLCRTLQGHGHWVNTMALSTD 297 Score = 44.3 bits (103), Expect = 3e-04 Identities = 27/89 (30%), Positives = 44/89 (49%), Gaps = 1/89 (1%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCE- 486 S+ + +G+ + SL GH ++ I S+ + +GS D TL +WD+ Q + Sbjct: 394 SIKLWDGRTGKYLASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDVKAQKLAMDLPG 453 Query: 485 HDEGVTCLAWLGSSRYVASGCIDGMVRIW 399 H + V + W + VASG D +RIW Sbjct: 454 HADEVYAVDWSPDGQRVASGGKDKCLRIW 482
>NLE1_HUMAN (Q9NVX2) Notchless homolog 1| Length = 484 Score = 67.4 bits (163), Expect = 4e-11 Identities = 38/132 (28%), Positives = 69/132 (52%), Gaps = 7/132 (5%) Frame = -2 Query: 620 SLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCE-HDEGVTCLAWLGSS 444 SL GH+ ++ + S ++A+GS D T+ WDL+ + TC+ H V ++W Sbjct: 108 SLEGHSEAVISVAFSPTGKYLASGSGDTTVRFWDLSTETPHFTCKGHRHWVLSISWSPDG 167 Query: 443 RYVASGCIDGMVRIWDSLSG-DLARTFSGHRDVVQSLA-----VSADGNSIVSVSTDKSA 282 + +ASGC +G + +WD +G + RT +GH + L+ + + + S S D S Sbjct: 168 KKLASGCKNGQILLWDPSTGKQVGRTLAGHSKWITGLSWEPLHANPECRYVASSSKDGSV 227 Query: 281 RVFDISMFK*EK 246 R++D + + E+ Sbjct: 228 RIWDTTAGRCER 239 Score = 59.3 bits (142), Expect = 1e-08 Identities = 35/116 (30%), Positives = 55/116 (47%), Gaps = 1/116 (0%) Frame = -2 Query: 617 LVGHTNSIECIGISSRYNWVATGSIDRTLIIWD-LARQAIRSTCEHDEGVTCLAWLGSSR 441 + GH I + S VA+ S D+++ +WD + + S H V +AW SR Sbjct: 367 MTGHQALINQVLFSPDSRIVASASFDKSIKLWDGRTGKYLASLRGHVAAVYQIAWSADSR 426 Query: 440 YVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVF 273 + SG D +++WD + LA GH D V ++ S DG + S DK R++ Sbjct: 427 LLVSGSSDSTLKVWDVKAQKLAMDLPGHADEVYAVDWSPDGQRVASGGKDKCLRIW 482 Score = 57.0 bits (136), Expect = 5e-08 Identities = 38/120 (31%), Positives = 59/120 (49%), Gaps = 7/120 (5%) Frame = -2 Query: 611 GHTNSIECIGISSRYNWVATGSIDRTLIIWD--LARQAIRSTCEHDEGVTCLAWLG---- 450 GH + + I S +A+G + +++WD +Q R+ H + +T L+W Sbjct: 153 GHRHWVLSISWSPDGKKLASGCKNGQILLWDPSTGKQVGRTLAGHSKWITGLSWEPLHAN 212 Query: 449 -SSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVF 273 RYVAS DG VRIWD+ +G R +GH V L DG + S S D++ +V+ Sbjct: 213 PECRYVASSSKDGSVRIWDTTAGRCERILTGHTQSVTCLRWGGDG-LLYSASQDRTIKVW 271 Score = 55.8 bits (133), Expect = 1e-07 Identities = 36/117 (30%), Positives = 56/117 (47%), Gaps = 10/117 (8%) Frame = -2 Query: 575 SRYNWV--------ATGSIDRTLIIWDLA--RQAIRSTCEHDEGVTCLAWLGSSRYVASG 426 SRYN V +GS D TL +W A ++ + H + + + SR VAS Sbjct: 330 SRYNLVRGQGPERLVSGSDDFTLFLWSPAEDKKPLTRMTGHQALINQVLFSPDSRIVASA 389 Query: 425 CIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFDISMFK 255 D +++WD +G + GH V +A SAD +VS S+D + +V+D+ K Sbjct: 390 SFDKSIKLWDGRTGKYLASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDVKAQK 446 Score = 53.5 bits (127), Expect = 5e-07 Identities = 37/114 (32%), Positives = 58/114 (50%), Gaps = 7/114 (6%) Frame = -2 Query: 641 NSGQVVG-SLVGHTNSI-----ECIGISSRYNWVATGSIDRTLIIWDL-ARQAIRSTCEH 483 ++G+ VG +L GH+ I E + + +VA+ S D ++ IWD A + R H Sbjct: 185 STGKQVGRTLAGHSKWITGLSWEPLHANPECRYVASSSKDGSVRIWDTTAGRCERILTGH 244 Query: 482 DEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSAD 321 + VTCL W G + S D +++W + G L RT GH V ++A+S D Sbjct: 245 TQSVTCLRW-GGDGLLYSASQDRTIKVWRAHDGVLCRTLQGHGHWVNTMALSTD 297 Score = 44.3 bits (103), Expect = 3e-04 Identities = 27/89 (30%), Positives = 44/89 (49%), Gaps = 1/89 (1%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCE- 486 S+ + +G+ + SL GH ++ I S+ + +GS D TL +WD+ Q + Sbjct: 394 SIKLWDGRTGKYLASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDVKAQKLAMDLPG 453 Query: 485 HDEGVTCLAWLGSSRYVASGCIDGMVRIW 399 H + V + W + VASG D +RIW Sbjct: 454 HADEVYAVDWSPDGQRVASGGKDKCLRIW 482
>PK1IP_CHICK (Q5ZKU8) p21-activated protein kinase-interacting protein 1-like| (PAK1-interacting protein 1-like) Length = 369 Score = 67.4 bits (163), Expect = 4e-11 Identities = 34/115 (29%), Positives = 68/115 (59%), Gaps = 1/115 (0%) Frame = -2 Query: 608 HTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTC-EHDEGVTCLAWLGSSRYVA 432 HT S+ + ++S+Y V TGS D ++ I+D+ ++ +H+ +TCL + G++ ++ Sbjct: 34 HTASLSAVAVNSKY--VVTGSRDESIQIYDMRKKVEHGALLQHNGTITCLEFYGTA-HLL 90 Query: 431 SGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFDI 267 SG DG++ IW++ + ++ H+ V SL++ G +SV TDK+ R +++ Sbjct: 91 SGAEDGLICIWNTKRWECLKSIKAHKGHVTSLSIHPSGKLALSVGTDKTLRTWNL 145
>WD51A_HUMAN (Q8NBT0) WD-repeat protein 51A| Length = 407 Score = 67.0 bits (162), Expect = 5e-11 Identities = 39/115 (33%), Positives = 61/115 (53%), Gaps = 2/115 (1%) Frame = -2 Query: 611 GHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQ--AIRSTCEHDEGVTCLAWLGSSRY 438 GH +++ C+ S +A+GS+D L++W + Q A R T H + VTC+ + S Sbjct: 17 GHRDAVTCVDFSINTKQLASGSMDSCLMVWHMKPQSRAYRFT-GHKDAVTCVNFSPSGHL 75 Query: 437 VASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVF 273 +ASG D VRIW + F H V+S+ +DG S V+ S DK+ +V+ Sbjct: 76 LASGSRDKTVRIWVPNVKGESTVFRAHTATVRSVHFCSDGQSFVTASDDKTVKVW 130 Score = 63.9 bits (154), Expect = 4e-10 Identities = 33/119 (27%), Positives = 61/119 (51%), Gaps = 1/119 (0%) Frame = -2 Query: 620 SLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLA-RQAIRSTCEHDEGVTCLAWLGSS 444 SL H N + C S + + S D+T+ +WD + R+ + S CEH VT + + S Sbjct: 140 SLSQHINWVRCAKFSPDGRLIVSASDDKTVKLWDKSSRECVHSYCEHGGFVTYVDFHPSG 199 Query: 443 RYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFDI 267 +A+ +D V++WD + L + + H V L+ GN +++ S+D + ++ D+ Sbjct: 200 TCIAAAGMDNTVKVWDVRTHRLLQHYQLHSAAVNGLSFHPSGNYLITASSDSTLKILDL 258 Score = 35.0 bits (79), Expect = 0.20 Identities = 22/73 (30%), Positives = 34/73 (46%), Gaps = 1/73 (1%) Frame = -2 Query: 608 HTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCEHDEG-VTCLAWLGSSRYVA 432 H+ ++ + N++ T S D TL I DL + T +G T +A+ + Y A Sbjct: 228 HSAAVNGLSFHPSGNYLITASSDSTLKILDLMEGRLLYTLHGHQGPATTVAFSRTGEYFA 287 Query: 431 SGCIDGMVRIWDS 393 SG D V +W S Sbjct: 288 SGGSDEQVMVWKS 300
>NLE1_BOVIN (Q58D20) Notchless homolog 1| Length = 485 Score = 67.0 bits (162), Expect = 5e-11 Identities = 38/133 (28%), Positives = 70/133 (52%), Gaps = 7/133 (5%) Frame = -2 Query: 620 SLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCE-HDEGVTCLAWLGSS 444 SL GH+ ++ + S ++A+GS D T+ WDL+ + TC+ H V ++W Sbjct: 109 SLEGHSEAVISVAFSPTGKYLASGSGDTTVRFWDLSTETPHFTCQGHRHWVLSISWSPDG 168 Query: 443 RYVASGCIDGMVRIWDSLSG-DLARTFSGHRDVVQSLA-----VSADGNSIVSVSTDKSA 282 + +ASGC +G + +WD +G + R +GH + +L+ + + + S S D S Sbjct: 169 KKLASGCKNGQILLWDPSTGKQVGRALTGHSKWITALSWEPLHANPECRYVASSSKDGSV 228 Query: 281 RVFDISMFK*EKS 243 RV+D + + E++ Sbjct: 229 RVWDTTAGRCERT 241 Score = 59.7 bits (143), Expect = 8e-09 Identities = 38/120 (31%), Positives = 60/120 (50%), Gaps = 7/120 (5%) Frame = -2 Query: 611 GHTNSIECIGISSRYNWVATGSIDRTLIIWD--LARQAIRSTCEHDEGVTCLAWLG---- 450 GH + + I S +A+G + +++WD +Q R+ H + +T L+W Sbjct: 154 GHRHWVLSISWSPDGKKLASGCKNGQILLWDPSTGKQVGRALTGHSKWITALSWEPLHAN 213 Query: 449 -SSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVF 273 RYVAS DG VR+WD+ +G RT +GH V L DG + S S D++ +V+ Sbjct: 214 PECRYVASSSKDGSVRVWDTTAGRCERTLTGHAQSVTCLRWGGDG-LLYSASQDRTIKVW 272 Score = 58.2 bits (139), Expect = 2e-08 Identities = 33/116 (28%), Positives = 55/116 (47%), Gaps = 1/116 (0%) Frame = -2 Query: 617 LVGHTNSIECIGISSRYNWVATGSIDRTLIIWD-LARQAIRSTCEHDEGVTCLAWLGSSR 441 + GH I + S +A+ S D+++ +WD + + S H V +AW SR Sbjct: 368 MTGHQALINQVVFSPDSRVIASASFDKSIKLWDGRTGKYLASLRGHVAAVYQIAWSADSR 427 Query: 440 YVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVF 273 + SG D +++WD + L+ GH D V ++ S DG + S DK R++ Sbjct: 428 LLVSGSSDSTLKVWDVKAQKLSTDLPGHADEVYAVDWSPDGQRVASGGKDKCLRIW 483 Score = 55.8 bits (133), Expect = 1e-07 Identities = 35/117 (29%), Positives = 56/117 (47%), Gaps = 10/117 (8%) Frame = -2 Query: 575 SRYNWV--------ATGSIDRTLIIWDLA--RQAIRSTCEHDEGVTCLAWLGSSRYVASG 426 SRYN V +GS D TL +W A ++ + H + + + SR +AS Sbjct: 331 SRYNLVRGQGPERLVSGSDDFTLFLWSPAEDKKPLARMTGHQALINQVVFSPDSRVIASA 390 Query: 425 CIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFDISMFK 255 D +++WD +G + GH V +A SAD +VS S+D + +V+D+ K Sbjct: 391 SFDKSIKLWDGRTGKYLASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDVKAQK 447 Score = 53.9 bits (128), Expect = 4e-07 Identities = 36/114 (31%), Positives = 59/114 (51%), Gaps = 7/114 (6%) Frame = -2 Query: 641 NSGQVVG-SLVGHTNSI-----ECIGISSRYNWVATGSIDRTLIIWDL-ARQAIRSTCEH 483 ++G+ VG +L GH+ I E + + +VA+ S D ++ +WD A + R+ H Sbjct: 186 STGKQVGRALTGHSKWITALSWEPLHANPECRYVASSSKDGSVRVWDTTAGRCERTLTGH 245 Query: 482 DEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSAD 321 + VTCL W G + S D +++W + G L RT GH V ++A+S D Sbjct: 246 AQSVTCLRW-GGDGLLYSASQDRTIKVWRAHDGVLCRTLQGHGHWVNTMALSTD 298 Score = 45.1 bits (105), Expect = 2e-04 Identities = 27/89 (30%), Positives = 45/89 (50%), Gaps = 1/89 (1%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCE- 486 S+ + +G+ + SL GH ++ I S+ + +GS D TL +WD+ Q + + Sbjct: 395 SIKLWDGRTGKYLASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDVKAQKLSTDLPG 454 Query: 485 HDEGVTCLAWLGSSRYVASGCIDGMVRIW 399 H + V + W + VASG D +RIW Sbjct: 455 HADEVYAVDWSPDGQRVASGGKDKCLRIW 483
>Y143_SYNY3 (P74442) Hypothetical WD-repeat protein slr0143| Length = 1191 Score = 67.0 bits (162), Expect = 5e-11 Identities = 36/115 (31%), Positives = 62/115 (53%) Frame = -2 Query: 617 LVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCEHDEGVTCLAWLGSSRY 438 L GH + + + ISS N +A+ S D T+ +W + +R H + + + + + Sbjct: 556 LTGHRDGVTSVAISSHKNLIASASRDGTVHLWTPQGEFLREFTGHTGSIYRVDFSPNGKI 615 Query: 437 VASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVF 273 A+ D V+IWD L G+L +T GH+D V S++ S DG + S S D++ R++ Sbjct: 616 FATAGQDQTVKIWD-LDGNLLQTLKGHQDSVYSVSFSPDGEILASTSRDRTVRLW 669 Score = 63.9 bits (154), Expect = 4e-10 Identities = 37/123 (30%), Positives = 56/123 (45%) Frame = -2 Query: 635 GQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCEHDEGVTCLAW 456 G+ + GHT SI + S AT D+T+ IWDL +++ H + V +++ Sbjct: 591 GEFLREFTGHTGSIYRVDFSPNGKIFATAGQDQTVKIWDLDGNLLQTLKGHQDSVYSVSF 650 Query: 455 LGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARV 276 +AS D VR+W SG GH V S DG ++VSV D R+ Sbjct: 651 SPDGEILASTSRDRTVRLWHWRSGKTLAVLGGHTKSVDDAQFSPDGQTLVSVCRDGQIRL 710 Query: 275 FDI 267 +D+ Sbjct: 711 WDL 713 Score = 49.3 bits (116), Expect = 1e-05 Identities = 32/118 (27%), Positives = 53/118 (44%) Frame = -2 Query: 638 SGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCEHDEGVTCLA 459 SG+ + L GHT S++ S + + D + +WDL IR + + Sbjct: 673 SGKTLAVLGGHTKSVDDAQFSPDGQTLVSVCRDGQIRLWDLDGNLIRQFGLPEVAFFGVN 732 Query: 458 WLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKS 285 W + +A DG VR+W G++ T SGH + V + + DG + S S++ S Sbjct: 733 WHPNGNLLAVAADDGTVRLWTP-QGEIKATLSGHDEFVTRVVFTPDGKQLFSSSSNGS 789 Score = 46.6 bits (109), Expect = 7e-05 Identities = 27/119 (22%), Positives = 52/119 (43%) Frame = -2 Query: 626 VGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCEHDEGVTCLAWLGS 447 +G+ + I + + +A G L +W+ IRS H + + L + + Sbjct: 990 LGNSIQRKEPIRSVSLHPTLPQLAAGDEQGNLTLWNFDGTLIRSIVAHGDRLNQLQYSPN 1049 Query: 446 SRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFD 270 +Y+ S +G +IW S+ G L T + +A+S D I + ++D R++D Sbjct: 1050 GKYLLSAGREGTAKIW-SVEGQLLHTLKSDPLPIDQIAISPDSQWIATAASDGMVRLWD 1107 Score = 41.2 bits (95), Expect = 0.003 Identities = 25/113 (22%), Positives = 53/113 (46%) Frame = -2 Query: 635 GQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCEHDEGVTCLAW 456 G ++ S+V H + + + S ++ + + T IW + Q + + + +A Sbjct: 1028 GTLIRSIVAHGDRLNQLQYSPNGKYLLSAGREGTAKIWSVEGQLLHTLKSDPLPIDQIAI 1087 Query: 455 LGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVS 297 S+++A+ DGMVR+WD G+L F+ + L + G +++V+ Sbjct: 1088 SPDSQWIATAASDGMVRLWDQ-QGNLRGEFTSTSGSLLGLDFNRQGQWLLAVA 1139 Score = 40.0 bits (92), Expect = 0.006 Identities = 24/101 (23%), Positives = 51/101 (50%) Frame = -2 Query: 566 NWVATGSIDRTLIIWDLARQAIRSTCEHDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLS 387 N +A + D T+ +W + + HDE VT + + + + S +G V W S S Sbjct: 738 NLLAVAADDGTVRLWTPQGEIKATLSGHDEFVTRVVFTPDGKQLFSSSSNGSVIHW-STS 796 Query: 386 GDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFDIS 264 G + + + G+ + + LA++++G + + + +V+D+S Sbjct: 797 GKMLKKYQGYPEAIFGLALASNGALLAIGAENNLVKVWDMS 837 Score = 30.8 bits (68), Expect = 3.8 Identities = 15/80 (18%), Positives = 38/80 (47%) Frame = -2 Query: 635 GQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCEHDEGVTCLAW 456 G++ +L GH + + + + + S + ++I W + + ++ + E + LA Sbjct: 756 GEIKATLSGHDEFVTRVVFTPDGKQLFSSSSNGSVIHWSTSGKMLKKYQGYPEAIFGLAL 815 Query: 455 LGSSRYVASGCIDGMVRIWD 396 + +A G + +V++WD Sbjct: 816 ASNGALLAIGAENNLVKVWD 835
>Y163_SYNY3 (Q55563) Hypothetical WD-repeat protein sll0163| Length = 1693 Score = 66.6 bits (161), Expect = 6e-11 Identities = 37/121 (30%), Positives = 54/121 (44%) Frame = -2 Query: 635 GQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCEHDEGVTCLAW 456 G+ +G GHT+ + S W+ T S D T +WDL+ Q H V W Sbjct: 1168 GREIGLCQGHTSWVRNAQFSPDGQWIVTCSADGTARLWDLSSQCFAVLKGHQNWVNNALW 1227 Query: 455 LGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARV 276 +++ + DG R+W S G T GH + S DG IV+ STD +AR+ Sbjct: 1228 SPDGQHIITSSSDGTARVW-SRHGKCLGTLRGHDHNIHGARFSLDGQKIVTYSTDNTARL 1286 Query: 275 F 273 + Sbjct: 1287 W 1287 Score = 65.1 bits (157), Expect = 2e-10 Identities = 38/126 (30%), Positives = 63/126 (50%) Frame = -2 Query: 641 NSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCEHDEGVTCL 462 N+G+ + L + +I S+ ++ T S D T IW++ + + H+ V Sbjct: 1453 NTGRELAVLRHYEKNIFAAEFSADGQFIVTASDDNTAGIWEIVGREVGICRGHEGPVYFA 1512 Query: 461 AWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSA 282 + SRY+ + +D RIWD L L T +GH+ +V S +GN I +VS D +A Sbjct: 1513 QFSADSRYILTASVDNTARIWDFLGRPLL-TLAGHQSIVYQARFSPEGNLIATVSADHTA 1571 Query: 281 RVFDIS 264 R++D S Sbjct: 1572 RLWDRS 1577 Score = 59.7 bits (143), Expect = 8e-09 Identities = 35/124 (28%), Positives = 58/124 (46%) Frame = -2 Query: 635 GQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCEHDEGVTCLAW 456 G+ VG GH + S+ ++ T S+D T IWD + + + H V + Sbjct: 1496 GREVGICRGHEGPVYFAQFSADSRYILTASVDNTARIWDFLGRPLLTLAGHQSIVYQARF 1555 Query: 455 LGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARV 276 +A+ D R+WD SG GH+ +V ++ S DG +V+ S D +AR+ Sbjct: 1556 SPEGNLIATVSADHTARLWDR-SGKTVAVLYGHQGLVGTVDWSPDGQMLVTASNDGTARL 1614 Query: 275 FDIS 264 +D+S Sbjct: 1615 WDLS 1618 Score = 58.5 bits (140), Expect = 2e-08 Identities = 35/123 (28%), Positives = 60/123 (48%) Frame = -2 Query: 635 GQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCEHDEGVTCLAW 456 G+ + +L GH + + S N +AT S D T +WD + + + H V + W Sbjct: 1537 GRPLLTLAGHQSIVYQARFSPEGNLIATVSADHTARLWDRSGKTVAVLYGHQGLVGTVDW 1596 Query: 455 LGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARV 276 + + + DG R+WD LSG T GH + V+S S DG +++ S D +A++ Sbjct: 1597 SPDGQMLVTASNDGTARLWD-LSGRELLTLEGHGNWVRSAEFSPDGRWVLTSSADGTAKL 1655 Query: 275 FDI 267 + + Sbjct: 1656 WPV 1658 Score = 57.4 bits (137), Expect = 4e-08 Identities = 32/123 (26%), Positives = 59/123 (47%) Frame = -2 Query: 635 GQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCEHDEGVTCLAW 456 G+ V L H + S W+ TGS D+T +W++ + + H + V + + Sbjct: 1373 GECVAVLADHQGWVREGQFSPDGQWIVTGSADKTAQLWNVLGKKLTVLRGHQDAVLNVRF 1432 Query: 455 LGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARV 276 S+Y+ + DG R+W++ +LA + + + SADG IV+ S D +A + Sbjct: 1433 SPDSQYIVTASKDGTARVWNNTGRELA-VLRHYEKNIFAAEFSADGQFIVTASDDNTAGI 1491 Query: 275 FDI 267 ++I Sbjct: 1492 WEI 1494 Score = 57.0 bits (136), Expect = 5e-08 Identities = 35/124 (28%), Positives = 59/124 (47%) Frame = -2 Query: 635 GQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCEHDEGVTCLAW 456 G+ V +L GH + + + S + ++ T D T IW+ A + + H + V + Sbjct: 1086 GEEVATLRGHEDWVRSVHFSPHHQFLVTSGQDNTARIWNFAGEQLTLCQGHADWVRNAEF 1145 Query: 455 LGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARV 276 + + + DG R+WD L G GH V++ S DG IV+ S D +AR+ Sbjct: 1146 NCHGQILLTASRDGTARLWD-LEGREIGLCQGHTSWVRNAQFSPDGQWIVTCSADGTARL 1204 Query: 275 FDIS 264 +D+S Sbjct: 1205 WDLS 1208 Score = 54.3 bits (129), Expect = 3e-07 Identities = 29/123 (23%), Positives = 62/123 (50%) Frame = -2 Query: 635 GQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCEHDEGVTCLAW 456 G+++ L GH +I + S+ + AT S D T+ +W + + + H++ V + + Sbjct: 1045 GELINVLRGHQEAITALDWSADGQYFATASADHTVKLWQRHGEEVATLRGHEDWVRSVHF 1104 Query: 455 LGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARV 276 +++ + D RIW + +G+ GH D V++ + G +++ S D +AR+ Sbjct: 1105 SPHHQFLVTSGQDNTARIW-NFAGEQLTLCQGHADWVRNAEFNCHGQILLTASRDGTARL 1163 Query: 275 FDI 267 +D+ Sbjct: 1164 WDL 1166 Score = 49.3 bits (116), Expect = 1e-05 Identities = 26/99 (26%), Positives = 45/99 (45%) Frame = -2 Query: 560 VATGSIDRTLIIWDLARQAIRSTCEHDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGD 381 V T + + +W + I H E +T L W +Y A+ D V++W G+ Sbjct: 1029 VLTATTNGIAYLWSFHGELINVLRGHQEAITALDWSADGQYFATASADHTVKLWQR-HGE 1087 Query: 380 LARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFDIS 264 T GH D V+S+ S +V+ D +AR+++ + Sbjct: 1088 EVATLRGHEDWVRSVHFSPHHQFLVTSGQDNTARIWNFA 1126 Score = 48.9 bits (115), Expect = 1e-05 Identities = 32/122 (26%), Positives = 55/122 (45%) Frame = -2 Query: 638 SGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCEHDEGVTCLA 459 +G+ + GH + + + + T S D T +WDL + I H V Sbjct: 1126 AGEQLTLCQGHADWVRNAEFNCHGQILLTASRDGTARLWDLEGREIGLCQGHTSWVRNAQ 1185 Query: 458 WLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSAR 279 + +++ + DG R+WD LS GH++ V + S DG I++ S+D +AR Sbjct: 1186 FSPDGQWIVTCSADGTARLWD-LSSQCFAVLKGHQNWVNNALWSPDGQHIITSSSDGTAR 1244 Query: 278 VF 273 V+ Sbjct: 1245 VW 1246 Score = 47.4 bits (111), Expect = 4e-05 Identities = 28/117 (23%), Positives = 56/117 (47%) Frame = -2 Query: 620 SLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCEHDEGVTCLAWLGSSR 441 +L GH++ + + + + + T S D+T +W + + +H V + + Sbjct: 1337 TLTGHSHWVRNAHFNPKGDRLLTVSRDKTARLWTTEGECVAVLADHQGWVREGQFSPDGQ 1396 Query: 440 YVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFD 270 ++ +G D ++W+ L G GH+D V ++ S D IV+ S D +ARV++ Sbjct: 1397 WIVTGSADKTAQLWNVL-GKKLTVLRGHQDAVLNVRFSPDSQYIVTASKDGTARVWN 1452 Score = 40.0 bits (92), Expect = 0.006 Identities = 29/123 (23%), Positives = 56/123 (45%) Frame = -2 Query: 635 GQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCEHDEGVTCLAW 456 G ++ L GH + S+ +V T S D+T WD++++ + H V + Sbjct: 1291 GTLLTILRGHQKEVYDADFSADGRFVFTVSADQTARQWDISQKDTITLTGHSHWVRNAHF 1350 Query: 455 LGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARV 276 + + D R+W + G+ + H+ V+ S DG IV+ S DK+A++ Sbjct: 1351 NPKGDRLLTVSRDKTARLW-TTEGECVAVLADHQGWVREGQFSPDGQWIVTGSADKTAQL 1409 Query: 275 FDI 267 +++ Sbjct: 1410 WNV 1412 Score = 38.5 bits (88), Expect = 0.018 Identities = 21/80 (26%), Positives = 35/80 (43%) Frame = -2 Query: 638 SGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCEHDEGVTCLA 459 SG+ V L GH + + S + T S D T +WDL+ + + + H V Sbjct: 1577 SGKTVAVLYGHQGLVGTVDWSPDGQMLVTASNDGTARLWDLSGRELLTLEGHGNWVRSAE 1636 Query: 458 WLGSSRYVASGCIDGMVRIW 399 + R+V + DG ++W Sbjct: 1637 FSPDGRWVLTSSADGTAKLW 1656
>GBLP_ORENI (O42249) Guanine nucleotide-binding protein beta subunit 2-like 1| (Receptor of activated protein kinase C) (RACK) Length = 317 Score = 66.6 bits (161), Expect = 6e-11 Identities = 41/127 (32%), Positives = 66/127 (51%), Gaps = 7/127 (5%) Frame = -2 Query: 629 VVGSLVGHTNSIECIGISSRY-NWVATGSIDRTLIIWDLARQAI------RSTCEHDEGV 471 V G+L GH+ + I + +Y + + + S D+++I+W L R RS H V Sbjct: 7 VRGTLKGHSGWVTQIATTPKYPDMILSASRDKSIIMWKLTRDETNYGIPQRSLKGHSHFV 66 Query: 470 TCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTD 291 + + ++ SG DG +R+WD +G R F GH V S+A SAD IVS S D Sbjct: 67 SDVVISSDGQFALSGAWDGTLRLWDLTTGLTTRRFVGHTKDVLSVAFSADNRQIVSGSRD 126 Query: 290 KSARVFD 270 K+ ++++ Sbjct: 127 KTIKLWN 133 Score = 53.1 bits (126), Expect = 7e-07 Identities = 33/138 (23%), Positives = 67/138 (48%), Gaps = 5/138 (3%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWD---LARQAIRST 492 ++ + + +G VGHT + + S+ + +GS D+T+ +W+ + + I+ Sbjct: 86 TLRLWDLTTGLTTRRFVGHTKDVLSVAFSADNRQIVSGSRDKTIKLWNTLGVCKYTIQDE 145 Query: 491 CEHDEGVTCLAWL--GSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADG 318 H E V+C+ + S+ + S D MV++W+ + L GH + ++ VS DG Sbjct: 146 -GHTEWVSCVRFSPNSSNPIIVSCGWDKMVKVWNLANCKLKTNHIGHTGYLNTVTVSPDG 204 Query: 317 NSIVSVSTDKSARVFDIS 264 + S D A ++D++ Sbjct: 205 SLCASGGKDGQAMLWDLN 222 Score = 50.8 bits (120), Expect = 4e-06 Identities = 39/134 (29%), Positives = 67/134 (50%), Gaps = 5/134 (3%) Frame = -2 Query: 641 NSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLAR-QAIRSTCEHDEGVTC 465 N G SL GH++ + + ISS + +G+ D TL +WDL R H + V Sbjct: 51 NYGIPQRSLKGHSHFVSDVVISSDGQFALSGAWDGTLRLWDLTTGLTTRRFVGHTKDVLS 110 Query: 464 LAWLGSSRYVASGCIDGMVRIWDSLSGDLARTF--SGHRDVVQSLAVSADGNS--IVSVS 297 +A+ +R + SG D +++W++L G T GH + V + S + ++ IVS Sbjct: 111 VAFSADNRQIVSGSRDKTIKLWNTL-GVCKYTIQDEGHTEWVSCVRFSPNSSNPIIVSCG 169 Query: 296 TDKSARVFDISMFK 255 DK +V++++ K Sbjct: 170 WDKMVKVWNLANCK 183 Score = 39.3 bits (90), Expect = 0.011 Identities = 31/127 (24%), Positives = 55/127 (43%), Gaps = 9/127 (7%) Frame = -2 Query: 614 VGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCEHDEGVTCLAWLGSSRYV 435 +GHT + + +S + A+G D ++WDL T + + + L + +RY Sbjct: 189 IGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDSGDVINALCF-SPNRYW 247 Query: 434 ASGCIDGMVRIWD--------SLSGDLARTFS-GHRDVVQSLAVSADGNSIVSVSTDKSA 282 ++IWD L ++ T S SLA SADG ++ + TD Sbjct: 248 LCAATGPSIKIWDLEGKIIVDELRQEVISTNSKAEPPQCTSLAWSADGQTLFAGYTDNLI 307 Query: 281 RVFDISM 261 RV+ +++ Sbjct: 308 RVWQVTI 314 Score = 35.4 bits (80), Expect = 0.15 Identities = 27/101 (26%), Positives = 44/101 (43%), Gaps = 10/101 (9%) Frame = -2 Query: 656 HIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLA--------RQAI 501 H+ +++SG V+ +L C + + ATG ++ IWDL RQ + Sbjct: 226 HLYTLDSGDVINAL--------CFSPNRYWLCAATGP---SIKIWDLEGKIIVDELRQEV 274 Query: 500 RSTCEHDEGVTC--LAWLGSSRYVASGCIDGMVRIWDSLSG 384 ST E C LAW + + +G D ++R+W G Sbjct: 275 ISTNSKAEPPQCTSLAWSADGQTLFAGYTDNLIRVWQVTIG 315
>GBLP_TRYBR (P69104) Guanine nucleotide-binding protein beta subunit-like| protein (Activated protein kinase C receptor homolog) (Track) Length = 318 Score = 66.6 bits (161), Expect = 6e-11 Identities = 36/137 (26%), Positives = 69/137 (50%), Gaps = 4/137 (2%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCE- 486 S+ + ++ +GQ +GHT + + S + +G D L +W++ + + + Sbjct: 90 SLRLWNLQNGQCQYKFLGHTKDVLSVAFSPDNRQIVSGGRDNALRVWNVKGECMHTLSRG 149 Query: 485 -HDEGVTCLAWLGS--SRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGN 315 H + V+C+ + S + + SG D +V++WD +G L GH + V S+ VS DG+ Sbjct: 150 AHTDWVSCVRFSPSLDAPVIVSGGWDNLVKVWDLATGRLVTDLKGHTNYVTSVTVSPDGS 209 Query: 314 SIVSVSTDKSARVFDIS 264 S D AR++D++ Sbjct: 210 LCASSDKDGVARLWDLT 226 Score = 48.1 bits (113), Expect = 2e-05 Identities = 36/132 (27%), Positives = 53/132 (40%), Gaps = 13/132 (9%) Frame = -2 Query: 623 GSLVGH---TNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCE----------H 483 G L GH S+ C V + S D+TL+ W S C H Sbjct: 7 GQLTGHRGWVTSLACPQTPETATKVVSTSRDKTLLSWGPNPDRHSSECSYGLPDRRLEGH 66 Query: 482 DEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVS 303 V+ +A + + S D +R+W+ +G F GH V S+A S D IVS Sbjct: 67 SAFVSDVALSNNGNFAVSASWDHSLRLWNLQNGQCQYKFLGHTKDVLSVAFSPDNRQIVS 126 Query: 302 VSTDKSARVFDI 267 D + RV+++ Sbjct: 127 GGRDNALRVWNV 138 Score = 46.6 bits (109), Expect = 7e-05 Identities = 37/139 (26%), Positives = 65/139 (46%), Gaps = 7/139 (5%) Frame = -2 Query: 659 VHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCEHD 480 V + + +G++V L GHTN + + +S + A+ D +WDL + S Sbjct: 178 VKVWDLATGRLVTDLKGHTNYVTSVTVSPDGSLCASSDKDGVARLWDLTKGEALSEMAAG 237 Query: 479 EGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGD----LARTFSGHRDVVQ---SLAVSAD 321 + + + +RY + +RI+D + D LA G + +V S+A SAD Sbjct: 238 APINQICF-SPNRYWMCAATEKGIRIFDLENKDIIVELAPEHQGSKKIVPECVSIAWSAD 296 Query: 320 GNSIVSVSTDKSARVFDIS 264 G+++ S TD RV+ +S Sbjct: 297 GSTLYSGYTDNVIRVWGVS 315
>GBLP_TRYBB (P69103) Guanine nucleotide-binding protein beta subunit-like| protein (Activated protein kinase C receptor homolog) Length = 318 Score = 66.6 bits (161), Expect = 6e-11 Identities = 36/137 (26%), Positives = 69/137 (50%), Gaps = 4/137 (2%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCE- 486 S+ + ++ +GQ +GHT + + S + +G D L +W++ + + + Sbjct: 90 SLRLWNLQNGQCQYKFLGHTKDVLSVAFSPDNRQIVSGGRDNALRVWNVKGECMHTLSRG 149 Query: 485 -HDEGVTCLAWLGS--SRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGN 315 H + V+C+ + S + + SG D +V++WD +G L GH + V S+ VS DG+ Sbjct: 150 AHTDWVSCVRFSPSLDAPVIVSGGWDNLVKVWDLATGRLVTDLKGHTNYVTSVTVSPDGS 209 Query: 314 SIVSVSTDKSARVFDIS 264 S D AR++D++ Sbjct: 210 LCASSDKDGVARLWDLT 226 Score = 48.1 bits (113), Expect = 2e-05 Identities = 36/132 (27%), Positives = 53/132 (40%), Gaps = 13/132 (9%) Frame = -2 Query: 623 GSLVGH---TNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCE----------H 483 G L GH S+ C V + S D+TL+ W S C H Sbjct: 7 GQLTGHRGWVTSLACPQTPETATKVVSTSRDKTLLSWGPNPDRHSSECSYGLPDRRLEGH 66 Query: 482 DEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVS 303 V+ +A + + S D +R+W+ +G F GH V S+A S D IVS Sbjct: 67 SAFVSDVALSNNGNFAVSASWDHSLRLWNLQNGQCQYKFLGHTKDVLSVAFSPDNRQIVS 126 Query: 302 VSTDKSARVFDI 267 D + RV+++ Sbjct: 127 GGRDNALRVWNV 138 Score = 46.6 bits (109), Expect = 7e-05 Identities = 37/139 (26%), Positives = 65/139 (46%), Gaps = 7/139 (5%) Frame = -2 Query: 659 VHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCEHD 480 V + + +G++V L GHTN + + +S + A+ D +WDL + S Sbjct: 178 VKVWDLATGRLVTDLKGHTNYVTSVTVSPDGSLCASSDKDGVARLWDLTKGEALSEMAAG 237 Query: 479 EGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGD----LARTFSGHRDVVQ---SLAVSAD 321 + + + +RY + +RI+D + D LA G + +V S+A SAD Sbjct: 238 APINQICF-SPNRYWMCAATEKGIRIFDLENKDIIVELAPEHQGSKKIVPECVSIAWSAD 296 Query: 320 GNSIVSVSTDKSARVFDIS 264 G+++ S TD RV+ +S Sbjct: 297 GSTLYSGYTDNVIRVWGVS 315
>KTNB1_CHICK (Q5ZIU8) Katanin p80 WD40-containing subunit B1 (Katanin p80| subunit B1) (p80 katanin) Length = 657 Score = 66.6 bits (161), Expect = 6e-11 Identities = 35/136 (25%), Positives = 71/136 (52%), Gaps = 1/136 (0%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQA-IRSTCE 486 S+ + + + +++ +L+GH +I + ++VA+GS+D + +WD+ R+ I Sbjct: 85 SIRVWDLEAAKILRTLLGHKANICSLDFHPYGSFVASGSLDTDIKLWDVRRKGCIFKYKS 144 Query: 485 HDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIV 306 H + V CL + +++AS D V++WD +G + F+GH V + + Sbjct: 145 HTQAVRCLRFSPDGKWLASAADDHTVKLWDLTAGKVMFEFTGHSGPVNVVEFHPSEYLLA 204 Query: 305 SVSTDKSARVFDISMF 258 S S+D++ R +D+ F Sbjct: 205 SGSSDRTIRFWDLEKF 220 Score = 64.3 bits (155), Expect = 3e-10 Identities = 37/136 (27%), Positives = 69/136 (50%), Gaps = 1/136 (0%) Frame = -2 Query: 659 VHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDL-ARQAIRSTCEH 483 V++ S+ + Q+ L GHT IE + IS++ + GS ++ +WDL A + +R+ H Sbjct: 45 VNVWSVKA-QLRHELTGHTTPIESLQISAKEELIVAGSQSGSIRVWDLEAAKILRTLLGH 103 Query: 482 DEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVS 303 + L + +VASG +D +++WD + H V+ L S DG + S Sbjct: 104 KANICSLDFHPYGSFVASGSLDTDIKLWDVRRKGCIFKYKSHTQAVRCLRFSPDGKWLAS 163 Query: 302 VSTDKSARVFDISMFK 255 + D + +++D++ K Sbjct: 164 AADDHTVKLWDLTAGK 179 Score = 48.5 bits (114), Expect = 2e-05 Identities = 27/118 (22%), Positives = 53/118 (44%), Gaps = 1/118 (0%) Frame = -2 Query: 617 LVGHTNSIECIGIS-SRYNWVATGSIDRTLIIWDLARQAIRSTCEHDEGVTCLAWLGSSR 441 +V H++++ + + S +ATG D + +W + Q H + L Sbjct: 16 IVAHSSNVSSLVLGKSTGRLLATGGDDCQVNVWSVKAQLRHELTGHTTPIESLQISAKEE 75 Query: 440 YVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFDI 267 + +G G +R+WD + + RT GH+ + SL G+ + S S D +++D+ Sbjct: 76 LIVAGSQSGSIRVWDLEAAKILRTLLGHKANICSLDFHPYGSFVASGSLDTDIKLWDV 133 Score = 34.7 bits (78), Expect = 0.26 Identities = 16/61 (26%), Positives = 31/61 (50%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCEH 483 +V + + +G+V+ GH+ + + +A+GS DRT+ WDL + + S E Sbjct: 169 TVKLWDLTAGKVMFEFTGHSGPVNVVEFHPSEYLLASGSSDRTIRFWDLEKFHVVSCIEE 228 Query: 482 D 480 + Sbjct: 229 E 229
>YKY4_CAEEL (Q17963) Hypothetical WD-repeat protein C14B1.4| Length = 376 Score = 66.2 bits (160), Expect = 8e-11 Identities = 37/138 (26%), Positives = 72/138 (52%), Gaps = 2/138 (1%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLAR-QAIRSTCE 486 ++ I I + ++ +L GH N + C + + + V +GS D ++ IWD+ I++ Sbjct: 152 TLKIFEIVTSRMTKTLKGHNNYVFCCNFNPQSSLVVSGSFDESVRIWDVKTGMCIKTLPA 211 Query: 485 HDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTF-SGHRDVVQSLAVSADGNSI 309 H + V+ +++ +ASG DG+VRIWD+ +G +T V + S +G I Sbjct: 212 HSDPVSAVSFNRDGSLIASGSYDGLVRIWDTANGQCIKTLVDDENPPVAFVKFSPNGKYI 271 Query: 308 VSVSTDKSARVFDISMFK 255 ++ + D + +++D S K Sbjct: 272 LASNLDSTLKLWDFSKGK 289 Score = 63.9 bits (154), Expect = 4e-10 Identities = 36/119 (30%), Positives = 60/119 (50%), Gaps = 1/119 (0%) Frame = -2 Query: 620 SLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCE-HDEGVTCLAWLGSS 444 +L GHT SI S ++ T S D+T+ IW++ T H GV +AW S Sbjct: 82 TLEGHTKSISSAKFSPCGKYLGTSSADKTVKIWNMDHMICERTLTGHKLGVNDIAWSSDS 141 Query: 443 RYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFDI 267 R V S D ++I++ ++ + +T GH + V + + +VS S D+S R++D+ Sbjct: 142 RCVVSASDDKTLKIFEIVTSRMTKTLKGHNNYVFCCNFNPQSSLVVSGSFDESVRIWDV 200 Score = 63.2 bits (152), Expect = 7e-10 Identities = 39/118 (33%), Positives = 59/118 (50%), Gaps = 1/118 (0%) Frame = -2 Query: 620 SLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCE-HDEGVTCLAWLGSS 444 +L GH + I SS V + S D+TL I+++ + T + H+ V C + S Sbjct: 124 TLTGHKLGVNDIAWSSDSRCVVSASDDKTLKIFEIVTSRMTKTLKGHNNYVFCCNFNPQS 183 Query: 443 RYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFD 270 V SG D VRIWD +G +T H D V +++ + DG+ I S S D R++D Sbjct: 184 SLVVSGSFDESVRIWDVKTGMCIKTLPAHSDPVSAVSFNRDGSLIASGSYDGLVRIWD 241 Score = 52.4 bits (124), Expect = 1e-06 Identities = 31/138 (22%), Positives = 67/138 (48%), Gaps = 6/138 (4%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCEH 483 SV I + +G + +L H++ + + + + +A+GS D + IWD A T Sbjct: 194 SVRIWDVKTGMCIKTLPAHSDPVSAVSFNRDGSLIASGSYDGLVRIWDTANGQCIKTLVD 253 Query: 482 DEG--VTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRD----VVQSLAVSAD 321 DE V + + + +Y+ + +D +++WD G + ++GH + + + +V+ Sbjct: 254 DENPPVAFVKFSPNGKYILASNLDSTLKLWDFSKGKTLKQYTGHENSKYCIFANFSVTG- 312 Query: 320 GNSIVSVSTDKSARVFDI 267 G I+S S D ++++ Sbjct: 313 GKWIISGSEDCKIYIWNL 330 Score = 37.0 bits (84), Expect = 0.053 Identities = 23/110 (20%), Positives = 50/110 (45%), Gaps = 5/110 (4%) Frame = -2 Query: 659 VHIVSINSGQVVGSLVGHTNS-IECIGISSRYNWVATGSIDRTLIIWDLAR-QAIRSTCE 486 V I +GQ + +LV N + + S ++ ++D TL +WD ++ + ++ Sbjct: 237 VRIWDTANGQCIKTLVDDENPPVAFVKFSPNGKYILASNLDSTLKLWDFSKGKTLKQYTG 296 Query: 485 HDEGVTCLAW---LGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVV 345 H+ C+ + +++ SG D + IW+ + ++ + GH V Sbjct: 297 HENSKYCIFANFSVTGGKWIISGSEDCKIYIWNLQTREIVQCLEGHTQPV 346 Score = 34.3 bits (77), Expect = 0.34 Identities = 24/89 (26%), Positives = 39/89 (43%), Gaps = 6/89 (6%) Frame = -2 Query: 641 NSGQVVGSLVGHTNSIECIGISSRYN---WVATGSIDRTLIIWDL-ARQAIRSTCEHDEG 474 + G+ + GH NS CI + W+ +GS D + IW+L R+ ++ H + Sbjct: 286 SKGKTLKQYTGHENSKYCIFANFSVTGGKWIISGSEDCKIYIWNLQTREIVQCLEGHTQP 345 Query: 473 VTCLAWLGSSRYVASGCI--DGMVRIWDS 393 V +ASG + D + IW S Sbjct: 346 VLASDCHPVQNIIASGALEPDNKIHIWRS 374
>WD51A_BOVIN (Q2TBP4) WD-repeat protein 51A| Length = 407 Score = 66.2 bits (160), Expect = 8e-11 Identities = 36/133 (27%), Positives = 69/133 (51%), Gaps = 1/133 (0%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWD-LARQAIRSTCE 486 +V + S + + + SL H N + C S + + S D+T+ +WD +R+ + S CE Sbjct: 126 TVKVWSTHRQKFLFSLSQHINWVRCAKFSPDGRLIVSASDDKTVKLWDKTSRECVHSYCE 185 Query: 485 HDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIV 306 H VT + + S +A+ +D V++WD + L + + H V +L+ GN +V Sbjct: 186 HGGFVTYVDFHPSGTCIAAAGMDNTVKVWDVRTHRLLQHYQLHSAAVNALSFHPSGNYLV 245 Query: 305 SVSTDKSARVFDI 267 + S+D + ++ D+ Sbjct: 246 TASSDSTLKILDL 258 Score = 61.6 bits (148), Expect = 2e-09 Identities = 35/114 (30%), Positives = 57/114 (50%), Gaps = 1/114 (0%) Frame = -2 Query: 611 GHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQA-IRSTCEHDEGVTCLAWLGSSRYV 435 GH +++ + S +A+GS+D L++W + Q H + VTC+ + S + Sbjct: 17 GHRDAVTSVDFSLNTKQLASGSMDSCLMVWHMKPQTRAYRFAGHKDAVTCVNFSPSGHLL 76 Query: 434 ASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVF 273 ASG D VRIW + F H V+S+ +DG S V+ S DK+ +V+ Sbjct: 77 ASGSRDKTVRIWVPNVKGESTVFRAHTATVRSVHFCSDGQSFVTASDDKTVKVW 130 Score = 47.4 bits (111), Expect = 4e-05 Identities = 31/116 (26%), Positives = 55/116 (47%), Gaps = 2/116 (1%) Frame = -2 Query: 611 GHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTC--EHDEGVTCLAWLGSSRY 438 GH +++ C+ S + +A+GS D+T+ IW + ST H V + + + Sbjct: 59 GHKDAVTCVNFSPSGHLLASGSRDKTVRIW-VPNVKGESTVFRAHTATVRSVHFCSDGQS 117 Query: 437 VASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFD 270 + D V++W + + S H + V+ S DG IVS S DK+ +++D Sbjct: 118 FVTASDDKTVKVWSTHRQKFLFSLSQHINWVRCAKFSPDGRLIVSASDDKTVKLWD 173 Score = 36.6 bits (83), Expect = 0.069 Identities = 22/73 (30%), Positives = 34/73 (46%), Gaps = 1/73 (1%) Frame = -2 Query: 608 HTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCEHDEG-VTCLAWLGSSRYVA 432 H+ ++ + N++ T S D TL I DL + T +G T +A+ + Y A Sbjct: 228 HSAAVNALSFHPSGNYLVTASSDSTLKILDLMEGRLLYTLHGHQGPATTVAFSRTGEYFA 287 Query: 431 SGCIDGMVRIWDS 393 SG D V +W S Sbjct: 288 SGGSDEQVMVWKS 300
>LIS1_CAEEL (Q9NDC9) Lissencephaly-1 homolog (Pronuclear migration abnormal| protein 1) Length = 404 Score = 66.2 bits (160), Expect = 8e-11 Identities = 38/143 (26%), Positives = 71/143 (49%), Gaps = 16/143 (11%) Frame = -2 Query: 644 INSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTC-EHDEGVT 468 I++G V + GH + + I IS+ A+ S+D+T+ +W A ++ + +H+ V Sbjct: 220 ISTGYCVYTFRGHNDWVRMIRISNDGTLFASASLDQTVTVWSFATKSAKLVLRDHEHAVE 279 Query: 467 CLAWLGSSRY---------------VASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLA 333 C+ W + Y + SG D ++ W+ +GD+ T H + V+ LA Sbjct: 280 CVEWAPDTAYTNVTGQQPEGNSTHILFSGSRDRSIKAWNINTGDVLFTLLAHENWVRGLA 339 Query: 332 VSADGNSIVSVSTDKSARVFDIS 264 G ++SV+ DK+ RV+++S Sbjct: 340 FHPKGKYLISVADDKTLRVWELS 362 Score = 65.9 bits (159), Expect = 1e-10 Identities = 35/135 (25%), Positives = 69/135 (51%), Gaps = 2/135 (1%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLAR--QAIRSTC 489 ++ + +GQ+ +L GHT+++ I I + + + S D ++ +WD + ++S Sbjct: 129 TIKVWDYETGQLERTLKGHTDAVNDIAIDAAGKQLVSCSSDLSIKLWDFGQTYDCLKSLK 188 Query: 488 EHDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSI 309 H+ V+ + +L + +V S D ++ WD +G TF GH D V+ + +S DG Sbjct: 189 GHEHTVSSVTFLPTGDFVLSASRDHTIKQWDISTGYCVYTFRGHNDWVRMIRISNDGTLF 248 Query: 308 VSVSTDKSARVFDIS 264 S S D++ V+ + Sbjct: 249 ASASLDQTVTVWSFA 263 Score = 50.1 bits (118), Expect = 6e-06 Identities = 22/56 (39%), Positives = 34/56 (60%) Frame = -2 Query: 437 VASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFD 270 +AS D +++WD +G L RT GH D V +A+ A G +VS S+D S +++D Sbjct: 121 MASCSEDATIKVWDYETGQLERTLKGHTDAVNDIAIDAAGKQLVSCSSDLSIKLWD 176 Score = 47.8 bits (112), Expect = 3e-05 Identities = 23/90 (25%), Positives = 51/90 (56%), Gaps = 1/90 (1%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCE- 486 S+ +IN+G V+ +L+ H N + + + ++ + + D+TL +W+L+ Q E Sbjct: 313 SIKAWNINTGDVLFTLLAHENWVRGLAFHPKGKYLISVADDKTLRVWELSAQRCMKAIEA 372 Query: 485 HDEGVTCLAWLGSSRYVASGCIDGMVRIWD 396 H+ V+ +A+ +S +V +G +D ++W+ Sbjct: 373 HEHFVSTVAFHQTSPFVITGSVDMSCKVWE 402
>LIN23_CAEEL (Q09990) F-box/WD-repeat protein lin-23 (Abnormal cell lineage| protein 23) Length = 665 Score = 66.2 bits (160), Expect = 8e-11 Identities = 38/118 (32%), Positives = 61/118 (51%), Gaps = 1/118 (0%) Frame = -2 Query: 617 LVGHTNSIECIGISSRYNWVATGSIDRTLIIWDL-ARQAIRSTCEHDEGVTCLAWLGSSR 441 LVGH ++ + RY + + S DRT+ +W + + +R+ H G+ CL + G R Sbjct: 341 LVGHRAAVNVVDFDDRY--IVSASGDRTIKVWSMDTLEFVRTLAGHRRGIACLQYRG--R 396 Query: 440 YVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFDI 267 V SG D +R+WD SG R GH ++V+ + D IVS + D +V+D+ Sbjct: 397 LVVSGSSDNTIRLWDIHSGVCLRVLEGHEELVR--CIRFDEKRIVSGAYDGKIKVWDL 452 Score = 48.9 bits (115), Expect = 1e-05 Identities = 26/90 (28%), Positives = 49/90 (54%), Gaps = 1/90 (1%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDL-ARQAIRSTCE 486 ++ + S+++ + V +L GH I C+ R V +GS D T+ +WD+ + +R Sbjct: 366 TIKVWSMDTLEFVRTLAGHRRGIACLQYRGRL--VVSGSSDNTIRLWDIHSGVCLRVLEG 423 Query: 485 HDEGVTCLAWLGSSRYVASGCIDGMVRIWD 396 H+E V C+ + + + SG DG +++WD Sbjct: 424 HEELVRCIRF--DEKRIVSGAYDGKIKVWD 451 Score = 45.1 bits (105), Expect = 2e-04 Identities = 30/99 (30%), Positives = 48/99 (48%), Gaps = 1/99 (1%) Frame = -2 Query: 560 VATGSIDRTLIIWDLARQAI-RSTCEHDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSG 384 + +G D T+ IWD + R H V CL + +R + SG D VR+WD +G Sbjct: 235 IVSGLRDNTIKIWDRKDYSCSRILSGHTGSVLCLQY--DNRVIISGSSDATVRVWDVETG 292 Query: 383 DLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFDI 267 + +T H + V L + +V+ S D+S V+D+ Sbjct: 293 ECIKTLIHHCEAVLHLRFA--NGIMVTCSKDRSIAVWDM 329
>TAF73_SCHPO (O74319) Transcription initiation factor TFIID subunit taf73| (Transcription initiation factor TFIID 73 kDa subunit) (TAFII-73) Length = 642 Score = 65.9 bits (159), Expect = 1e-10 Identities = 37/116 (31%), Positives = 59/116 (50%), Gaps = 1/116 (0%) Frame = -2 Query: 611 GHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQA-IRSTCEHDEGVTCLAWLGSSRYV 435 GH I + S + AT S D+T +WD+ A +R H V C+++ ++ Y+ Sbjct: 443 GHNAPIWDVQFSPFGYYFATASHDQTARLWDVEHAAPLRVFVGHQNDVDCVSFHPNAAYL 502 Query: 434 ASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFDI 267 A+G D R+WD +G R F+ H V +L +SADG S+ S +V+D+ Sbjct: 503 ATGSSDHTTRMWDVRTGGTVRVFNAHHSPVSALCMSADGLSLASADESGIIKVWDL 558 Score = 62.8 bits (151), Expect = 9e-10 Identities = 34/118 (28%), Positives = 56/118 (47%), Gaps = 1/118 (0%) Frame = -2 Query: 614 VGHTNSIECIGISSRYNWVATGSIDRTLIIWDL-ARQAIRSTCEHDEGVTCLAWLGSSRY 438 VGH N ++C+ ++ATGS D T +WD+ +R H V+ L Sbjct: 484 VGHQNDVDCVSFHPNAAYLATGSSDHTTRMWDVRTGGTVRVFNAHHSPVSALCMSADGLS 543 Query: 437 VASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFDIS 264 +AS G++++WD S + +F H +V SL+ S D +VS D +D++ Sbjct: 544 LASADESGIIKVWDLRSSNQHVSFVKHSSIVYSLSFSYDNKILVSGGADTDVNFWDLT 601 Score = 30.8 bits (68), Expect = 3.8 Identities = 14/58 (24%), Positives = 28/58 (48%) Frame = -2 Query: 440 YVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFDI 267 ++ S DG R+W + ++GH + + S G + S D++AR++D+ Sbjct: 417 FILSCSEDGFTRLWSKDTKSTIVKYAGHNAPIWDVQFSPFGYYFATASHDQTARLWDV 474
>GBLP_BRARE (O42248) Guanine nucleotide-binding protein beta subunit 2-like 1| (Receptor of activated protein kinase C) (RACK) Length = 317 Score = 65.9 bits (159), Expect = 1e-10 Identities = 40/127 (31%), Positives = 66/127 (51%), Gaps = 7/127 (5%) Frame = -2 Query: 629 VVGSLVGHTNSIECIGISSRY-NWVATGSIDRTLIIWDLARQAI------RSTCEHDEGV 471 V G+L GH+ + I + ++ + + + S D+T+I+W L R R+ H V Sbjct: 7 VRGTLKGHSGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFV 66 Query: 470 TCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTD 291 + + ++ SG DG +R+WD +G R F GH V S+A SAD IVS S D Sbjct: 67 SDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSADNRQIVSGSRD 126 Query: 290 KSARVFD 270 K+ ++++ Sbjct: 127 KTIKLWN 133 Score = 54.3 bits (129), Expect = 3e-07 Identities = 33/138 (23%), Positives = 67/138 (48%), Gaps = 5/138 (3%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWD---LARQAIRST 492 ++ + + +G VGHT + + S+ + +GS D+T+ +W+ + + I+ Sbjct: 86 TLRLWDLTTGTTTRRFVGHTKDVLSVAFSADNRQIVSGSRDKTIKLWNTLGVCKYTIQDD 145 Query: 491 CEHDEGVTCLAWL--GSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADG 318 H E V+C+ + S+ + S D MV++W+ + L GH + ++ VS DG Sbjct: 146 -SHTEWVSCVRFSPNSSNPIIVSCGWDKMVKVWNLANCKLKTNHIGHTGYLNTVTVSPDG 204 Query: 317 NSIVSVSTDKSARVFDIS 264 + S D A ++D++ Sbjct: 205 SLCASGGKDGQAMLWDLN 222 Score = 48.5 bits (114), Expect = 2e-05 Identities = 38/134 (28%), Positives = 66/134 (49%), Gaps = 5/134 (3%) Frame = -2 Query: 641 NSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLAR-QAIRSTCEHDEGVTC 465 N G +L GH++ + + ISS + +GS D TL +WDL R H + V Sbjct: 51 NYGIPQRALRGHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLS 110 Query: 464 LAWLGSSRYVASGCIDGMVRIWDSLSGDLARTF--SGHRDVVQSLAVSADGNS--IVSVS 297 +A+ +R + SG D +++W++L G T H + V + S + ++ IVS Sbjct: 111 VAFSADNRQIVSGSRDKTIKLWNTL-GVCKYTIQDDSHTEWVSCVRFSPNSSNPIIVSCG 169 Query: 296 TDKSARVFDISMFK 255 DK +V++++ K Sbjct: 170 WDKMVKVWNLANCK 183 Score = 41.2 bits (95), Expect = 0.003 Identities = 32/127 (25%), Positives = 55/127 (43%), Gaps = 9/127 (7%) Frame = -2 Query: 614 VGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCEHDEGVTCLAWLGSSRYV 435 +GHT + + +S + A+G D ++WDL T + + + L + +RY Sbjct: 189 IGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGGDTINALCF-SPNRYW 247 Query: 434 ASGCIDGMVRIWD--------SLSGDLARTFS-GHRDVVQSLAVSADGNSIVSVSTDKSA 282 ++IWD L D+ T S SLA SADG ++ + TD Sbjct: 248 LCAATGPSIKIWDLEGKIIVDELRQDIITTNSKAEPPQCTSLAWSADGQTLFAGYTDNLI 307 Query: 281 RVFDISM 261 RV+ +++ Sbjct: 308 RVWQVTI 314 Score = 31.2 bits (69), Expect = 2.9 Identities = 25/101 (24%), Positives = 42/101 (41%), Gaps = 10/101 (9%) Frame = -2 Query: 656 HIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLA--------RQAI 501 H+ +++ G + +L C + + ATG ++ IWDL RQ I Sbjct: 226 HLYTLDGGDTINAL--------CFSPNRYWLCAATGP---SIKIWDLEGKIIVDELRQDI 274 Query: 500 RSTCEHDEGVTC--LAWLGSSRYVASGCIDGMVRIWDSLSG 384 +T E C LAW + + +G D ++R+W G Sbjct: 275 ITTNSKAEPPQCTSLAWSADGQTLFAGYTDNLIRVWQVTIG 315
>PWP2_NEUCR (Q9C270) Periodic tryptophan protein 2 homolog| Length = 899 Score = 65.1 bits (157), Expect = 2e-10 Identities = 42/134 (31%), Positives = 66/134 (49%), Gaps = 3/134 (2%) Frame = -2 Query: 659 VHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCEHD 480 + + SG + + HT+ I S + N + T S+D ++ WDL R T Sbjct: 363 IKVWDTESGFCIVTFTEHTSGITACEFSKKGNVLFTSSLDGSIRAWDLIRYRNFRTFTAP 422 Query: 479 EGVT--CLAWLGSSRYVASGCIDGM-VRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSI 309 E ++ C+A S VA+G +D + IW +G L SGH V SLA + +G + Sbjct: 423 ERLSFSCMAVDPSGEIVAAGSVDSFDIHIWSVQTGQLLDRLSGHEGPVSSLAFAPNGGLL 482 Query: 308 VSVSTDKSARVFDI 267 VS S D++AR++ I Sbjct: 483 VSGSWDRTARIWSI 496 Score = 48.5 bits (114), Expect = 2e-05 Identities = 28/118 (23%), Positives = 57/118 (48%), Gaps = 2/118 (1%) Frame = -2 Query: 602 NSIECIGISSRYNWVATGSIDR-TLIIWDLARQA-IRSTCEHDEGVTCLAWLGSSRYVAS 429 N I+ + I+ W+A G+ L++W+ ++ I H + + L + + + + Sbjct: 297 NEIDFVTINKSGEWLAFGASKLGQLLVWEWQSESYILKQQGHFDSMNSLVYSPDGQRIVT 356 Query: 428 GCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFDISMFK 255 DG +++WD+ SG TF+ H + + S GN + + S D S R +D+ ++ Sbjct: 357 VADDGKIKVWDTESGFCIVTFTEHTSGITACEFSKKGNVLFTSSLDGSIRAWDLIRYR 414 Score = 47.0 bits (110), Expect = 5e-05 Identities = 27/105 (25%), Positives = 47/105 (44%), Gaps = 1/105 (0%) Frame = -2 Query: 659 VHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRST-CEH 483 +HI S+ +GQ++ L GH + + + + +GS DRT IW + + S + Sbjct: 449 IHIWSVQTGQLLDRLSGHEGPVSSLAFAPNGGLLVSGSWDRTARIWSIFNRTQTSEPLQL 508 Query: 482 DEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDV 348 + V +A+ S +A +DG + W + G RDV Sbjct: 509 NSDVLDIAFRPDSLQIAISTLDGNLSFWSVSEAEQQAGLDGRRDV 553 Score = 34.7 bits (78), Expect = 0.26 Identities = 25/75 (33%), Positives = 32/75 (42%), Gaps = 2/75 (2%) Frame = -2 Query: 488 EHDEGVTCLAWLGSSRYVASGCIDGMVRIW--DSLSGDLARTFSGHRDVVQSLAVSADGN 315 +H + V + W SR+ + D RIW D G SGHR V S D Sbjct: 149 QHFDDVRHIEWSHDSRFFLTSSKDLTARIWSVDQEEGFTPTVLSGHRQGVVGAWFSKDQE 208 Query: 314 SIVSVSTDKSARVFD 270 +I +VS K VFD Sbjct: 209 TIYTVS--KDGAVFD 221
>PRP46_DEBHA (Q6BU94) Pre-mRNA-splicing factor PRP46 (Pre-mRNA-processing| protein 46) Length = 417 Score = 65.1 bits (157), Expect = 2e-10 Identities = 39/138 (28%), Positives = 68/138 (49%), Gaps = 6/138 (4%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQ------AI 501 ++ I + S + ++ GH + + +SSRY ++ +GS D+T+ WDL R I Sbjct: 145 TIKIWDLASLNLKATITGHIMGVRSLAVSSRYPYLFSGSEDKTVKCWDLERTNSLLGCQI 204 Query: 500 RSTCEHDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSAD 321 R+ H G+ +A + +G D ++R+WD S SGHR + S+A Sbjct: 205 RNYHGHVGGIYAMALHPELDLLFTGGRDSVIRVWDLRSRTEIMVLSGHRSDITSIASQIG 264 Query: 320 GNSIVSVSTDKSARVFDI 267 I++ S D + R++DI Sbjct: 265 DPQIITSSMDATIRLWDI 282 Score = 53.1 bits (126), Expect = 7e-07 Identities = 35/105 (33%), Positives = 52/105 (49%), Gaps = 6/105 (5%) Frame = -2 Query: 563 WVATGSIDRTLIIWDLARQAIRSTCE-HDEGVTCLAWLGSSRYVASGCIDGMVRIWD--- 396 W TGS D T+ IWDLA +++T H GV LA Y+ SG D V+ WD Sbjct: 136 WFVTGSSDSTIKIWDLASLNLKATITGHIMGVRSLAVSSRYPYLFSGSEDKTVKCWDLER 195 Query: 395 --SLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFDI 267 SL G R + GH + ++A+ + + + + D RV+D+ Sbjct: 196 TNSLLGCQIRNYHGHVGGIYAMALHPELDLLFTGGRDSVIRVWDL 240 Score = 44.3 bits (103), Expect = 3e-04 Identities = 28/133 (21%), Positives = 57/133 (42%), Gaps = 3/133 (2%) Frame = -2 Query: 659 VHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIR-STCEH 483 + + + S + L GH + I I + T S+D T+ +WD+ + + + H Sbjct: 235 IRVWDLRSRTEIMVLSGHRSDITSIASQIGDPQIITSSMDATIRLWDIRKATTQLALTHH 294 Query: 482 DEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTF--SGHRDVVQSLAVSADGNSI 309 + + +A + SG G ++ W G+L F SG ++ +L+++ N++ Sbjct: 295 SKSIRLMAMHPQEMTMCSGDTSGNLKEWLLPGGELLNEFGHSGENKIINTLSINPSNNTL 354 Query: 308 VSVSTDKSARVFD 270 S D +D Sbjct: 355 FSGYDDGRMEFYD 367 Score = 41.2 bits (95), Expect = 0.003 Identities = 21/61 (34%), Positives = 37/61 (60%) Frame = -2 Query: 449 SSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFD 270 ++++ +G D ++IWD S +L T +GH V+SLAVS+ + S S DK+ + +D Sbjct: 133 TNKWFVTGSSDSTIKIWDLASLNLKATITGHIMGVRSLAVSSRYPYLFSGSEDKTVKCWD 192 Query: 269 I 267 + Sbjct: 193 L 193
>POF11_SCHPO (Q09855) F-box/WD-repeat protein pof11| Length = 506 Score = 65.1 bits (157), Expect = 2e-10 Identities = 38/119 (31%), Positives = 62/119 (52%), Gaps = 1/119 (0%) Frame = -2 Query: 617 LVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLAR-QAIRSTCEHDEGVTCLAWLGSSR 441 L GH S+ + SS+ + T S DRTL WD+ IR H G+ C + G + Sbjct: 343 LRGHLASVNSVQYSSKTGLIVTASSDRTLRTWDITTGHCIRIIHAHQRGIACAQYNG--K 400 Query: 440 YVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFDIS 264 ++ SG D +RI+++ SG L R GH D++++ V + IVS D + R+++ + Sbjct: 401 FIVSGSSDLTIRIFEASSGKLLRMLQGHEDLIRT--VRFNDEKIVSGGYDGTVRIWNFN 457 Score = 62.8 bits (151), Expect = 9e-10 Identities = 43/138 (31%), Positives = 70/138 (50%), Gaps = 5/138 (3%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLA-RQAIRSTCE 486 +V + +NS ++ L GH+ S+ C+ R N + +GS D T+IIWD R+ ++ Sbjct: 242 TVSVWDVNSRFILYKLYGHSGSVLCLDFCRRRNLLVSGSSDSTIIIWDWQNRRPLKVYFG 301 Query: 485 HDEGVTCLAWLGSSRYVASGCIDGMVRIW--DSLSGDLA--RTFSGHRDVVQSLAVSADG 318 H + V L + S Y+ S D R+W D+ S A GH V S+ S+ Sbjct: 302 HTDNV--LGVVVSENYIISSSRDHTARVWRLDATSPAEACMHVLRGHLASVNSVQYSSKT 359 Query: 317 NSIVSVSTDKSARVFDIS 264 IV+ S+D++ R +DI+ Sbjct: 360 GLIVTASSDRTLRTWDIT 377 Score = 50.8 bits (120), Expect = 4e-06 Identities = 34/111 (30%), Positives = 54/111 (48%), Gaps = 1/111 (0%) Frame = -2 Query: 602 NSIECIGISSRYNWVATGSIDRTLIIWDL-ARQAIRSTCEHDEGVTCLAWLGSSRYVASG 426 +S+ C+ + +GS DRT+ +WD+ +R + H V CL + + SG Sbjct: 222 DSVYCVQYDDEI--MVSGSKDRTVSVWDVNSRFILYKLYGHSGSVLCLDFCRRRNLLVSG 279 Query: 425 CIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVF 273 D + IWD + + + GH D V + VS N I+S S D +ARV+ Sbjct: 280 SSDSTIIIWDWQNRRPLKVYFGHTDNVLGVVVSE--NYIISSSRDHTARVW 328
>GBLP_NICPL (P93340) Guanine nucleotide-binding protein beta subunit-like| protein Length = 326 Score = 65.1 bits (157), Expect = 2e-10 Identities = 40/125 (32%), Positives = 60/125 (48%), Gaps = 7/125 (5%) Frame = -2 Query: 623 GSLVGHTNSIECIGIS-SRYNWVATGSIDRTLIIWDLARQAI------RSTCEHDEGVTC 465 G++ HT+ + I + + T S D+++I+W L + R H V Sbjct: 10 GTMRAHTDWVTAIATPVDNSDMIVTSSRDKSIIVWSLTKDGPQYGVPRRRLTGHGHFVQD 69 Query: 464 LAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKS 285 + + SG DG +R+WD +G AR F GH V S+A SAD IVS S DKS Sbjct: 70 VVLSSDGMFALSGSWDGELRLWDLQAGTTARRFVGHTKDVLSVAFSADNRQIVSASRDKS 129 Query: 284 ARVFD 270 R+++ Sbjct: 130 IRLWN 134 Score = 53.9 bits (128), Expect = 4e-07 Identities = 32/132 (24%), Positives = 63/132 (47%), Gaps = 5/132 (3%) Frame = -2 Query: 644 INSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDL---ARQAIRSTCEHDEG 474 + +G VGHT + + S+ + + S D+++ +W+ + I+ H + Sbjct: 93 LQAGTTARRFVGHTKDVLSVAFSADNRQIVSASRDKSIRLWNTLGECKYIIQDGDSHSDW 152 Query: 473 VTCLAWLGSSRY--VASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSV 300 V+C+ + ++ + SG D V+IW+ + L T +GH V + AVS DG+ S Sbjct: 153 VSCVRFSPNNLQPTIVSGSWDRTVKIWNLTNCKLRATLAGHTGYVNTTAVSPDGSLCASG 212 Query: 299 STDKSARVFDIS 264 D ++D++ Sbjct: 213 GKDGVILLWDLA 224 Score = 48.1 bits (113), Expect = 2e-05 Identities = 41/153 (26%), Positives = 68/153 (44%), Gaps = 18/153 (11%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCEH 483 +V I ++ + ++ +L GHT + +S + A+G D +++WDLA + E Sbjct: 175 TVKIWNLTNCKLRATLAGHTGYVNTTAVSPDGSLCASGGKDGVILLWDLAEGKKLYSLES 234 Query: 482 DEGVTCLAWLGSSRYVASGCIDGMVRIW--------DSLSGDLAR--------TFSGHRD 351 + L + +RY + ++IW D L DL + T SG Sbjct: 235 GSIIHSLCF-SPNRYWLCAATESSIKIWDLESKTIVDDLKVDLKQESEMSAEGTASGKNK 293 Query: 350 VV--QSLAVSADGNSIVSVSTDKSARVFDISMF 258 V+ SL SADG+++ S TD RV+ I F Sbjct: 294 VIYCTSLGWSADGSTLFSGYTDGLIRVWGIGRF 326 Score = 30.4 bits (67), Expect = 4.9 Identities = 21/79 (26%), Positives = 37/79 (46%), Gaps = 6/79 (7%) Frame = -2 Query: 485 HDEGVTCLAW-LGSSRYVASGCIDGMVRIWDSLS-----GDLARTFSGHRDVVQSLAVSA 324 H + VT +A + +S + + D + +W G R +GH VQ + +S+ Sbjct: 15 HTDWVTAIATPVDNSDMIVTSSRDKSIIVWSLTKDGPQYGVPRRRLTGHGHFVQDVVLSS 74 Query: 323 DGNSIVSVSTDKSARVFDI 267 DG +S S D R++D+ Sbjct: 75 DGMFALSGSWDGELRLWDL 93
>SCONB_EMENI (Q00659) Sulfur metabolite repression control protein| Length = 678 Score = 65.1 bits (157), Expect = 2e-10 Identities = 35/115 (30%), Positives = 64/115 (55%), Gaps = 1/115 (0%) Frame = -2 Query: 611 GHTNSIECIGISSRYNWVATGSIDRTLIIWDLAR-QAIRSTCEHDEGVTCLAWLGSSRYV 435 GHTN + C+ N +ATGS D T+ IWD + +R+ H+ G+ CL + + Sbjct: 347 GHTNGVMCLQFED--NILATGSYDTTIKIWDTETGEELRTLRGHESGIRCLQF--DDTKL 402 Query: 434 ASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFD 270 SG +D +++W+ +G+ T++GHR V + + D + + S S DK+ ++++ Sbjct: 403 ISGSMDRTIKVWNWRTGECISTYTGHRGGV--IGLHFDASILASGSVDKTVKIWN 455 Score = 52.8 bits (125), Expect = 9e-07 Identities = 32/109 (29%), Positives = 56/109 (51%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCEH 483 ++ + + +G+ + + GH + IG+ + +A+GS+D+T+ IW+ ++ S H Sbjct: 410 TIKVWNWRTGECISTYTGHRGGV--IGLHFDASILASGSVDKTVKIWNFEDKSTFSLRGH 467 Query: 482 DEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSL 336 + V + SSR V S D VR+WD + RTF GH VQ + Sbjct: 468 TDWVNAVRVDTSSRTVFSASDDCTVRLWDLDTKTCIRTFHGHVGQVQQV 516 Score = 47.4 bits (111), Expect = 4e-05 Identities = 25/85 (29%), Positives = 45/85 (52%) Frame = -2 Query: 524 WDLARQAIRSTCEHDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVV 345 W R +I++ H GV CL + +A+G D ++IWD+ +G+ RT GH + Sbjct: 335 WKYGRCSIKTFKGHTNGVMCLQF--EDNILATGSYDTTIKIWDTETGEELRTLRGHESGI 392 Query: 344 QSLAVSADGNSIVSVSTDKSARVFD 270 + L D ++S S D++ +V++ Sbjct: 393 RCL--QFDDTKLISGSMDRTIKVWN 415 Score = 45.8 bits (107), Expect = 1e-04 Identities = 24/79 (30%), Positives = 42/79 (53%), Gaps = 1/79 (1%) Frame = -2 Query: 563 WVATGSIDRTLIIWDLAR-QAIRSTCEHDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLS 387 ++ T ++D T+ +W+ + +R+ H EGV L + + SG D M++IWD + Sbjct: 581 YMVTSALDSTIRLWETTTGRCLRTFFGHLEGVWALG--ADTLRIVSGAEDRMIKIWDPRT 638 Query: 386 GDLARTFSGHRDVVQSLAV 330 G RTF+GH V + + Sbjct: 639 GKCERTFTGHSGPVTCIGL 657 Score = 42.4 bits (98), Expect = 0.001 Identities = 22/67 (32%), Positives = 39/67 (58%) Frame = -2 Query: 443 RYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFDIS 264 RY+ + +D +R+W++ +G RTF GH + V A+ AD IVS + D+ +++D Sbjct: 580 RYMVTSALDSTIRLWETTTGRCLRTFFGHLEGV--WALGADTLRIVSGAEDRMIKIWDPR 637 Query: 263 MFK*EKS 243 K E++ Sbjct: 638 TGKCERT 644 Score = 33.5 bits (75), Expect = 0.58 Identities = 24/89 (26%), Positives = 45/89 (50%), Gaps = 1/89 (1%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWD-LARQAIRSTCE 486 ++ + +G+ + + GH + +G + + +G+ DR + IWD + R+ Sbjct: 590 TIRLWETTTGRCLRTFFGHLEGVWALGADTLR--IVSGAEDRMIKIWDPRTGKCERTFTG 647 Query: 485 HDEGVTCLAWLGSSRYVASGCIDGMVRIW 399 H VTC+ LG SR+ A+G D VR++ Sbjct: 648 HSGPVTCIG-LGDSRF-ATGSEDCEVRMY 674
>WDR3_HUMAN (Q9UNX4) WD-repeat protein 3| Length = 943 Score = 64.7 bits (156), Expect = 2e-10 Identities = 42/132 (31%), Positives = 67/132 (50%), Gaps = 1/132 (0%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLA-RQAIRSTCE 486 +V I +++ + SL GH + C+ IS +ATGS DR + IW L +S Sbjct: 572 TVKIFYVDTLKFFLSLYGHKLPVICMDISHDGALIATGSADRNVKIWGLDFGDCHKSLFA 631 Query: 485 HDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIV 306 HD+ V L ++ S + D ++ WD+ + +T GH + LAVS G+ +V Sbjct: 632 HDDSVMYLQFVPKSHLFFTAGKDHKIKQWDADKFEHIQTLEGHHQEIWCLAVSPSGDYVV 691 Query: 305 SVSTDKSARVFD 270 S S DKS R+++ Sbjct: 692 SSSHDKSLRLWE 703 Score = 55.1 bits (131), Expect = 2e-07 Identities = 34/134 (25%), Positives = 66/134 (49%), Gaps = 1/134 (0%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQA-IRSTCE 486 S+ I S+ SG+ + GH +I + +A+GS D +I+WD+ ++ + Sbjct: 88 SIRIFSLLSGEGNVTFNGHKAAITTLKYDQLGGRLASGSKDTDIIVWDVINESGLYRLKG 147 Query: 485 HDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIV 306 H + +T +L + + D MV+ WD + +T GHR V L + ++ ++ Sbjct: 148 HKDAITQALFLREKNLLVTSGKDTMVKWWDLDTQHCFKTMVGHRTEVWGLVLLSEEKRLI 207 Query: 305 SVSTDKSARVFDIS 264 + ++D RV+DI+ Sbjct: 208 TGASDSELRVWDIA 221 Score = 48.9 bits (115), Expect = 1e-05 Identities = 38/122 (31%), Positives = 59/122 (48%), Gaps = 1/122 (0%) Frame = -2 Query: 629 VVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLAR-QAIRSTCEHDEGVTCLAWL 453 V+GS G+ + G RY VA + + + IWDL + + I + VTCL Sbjct: 18 VIGSQKGNIVFVTLRGEKGRY--VAVPACEH-VFIWDLRKGEKILILQGLKQEVTCLCPS 74 Query: 452 GSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVF 273 ++A G DG +RI+ LSG+ TF+GH+ + +L G + S S D V+ Sbjct: 75 PDGLHLAVGYEDGSIRIFSLLSGEGNVTFNGHKAAITTLKYDQLGGRLASGSKDTDIIVW 134 Query: 272 DI 267 D+ Sbjct: 135 DV 136 Score = 32.3 bits (72), Expect = 1.3 Identities = 25/113 (22%), Positives = 43/113 (38%), Gaps = 1/113 (0%) Frame = -2 Query: 590 CIGISSRYNWVATGSIDRTLIIWDL-ARQAIRSTCEHDEGVTCLAWLGSSRYVASGCIDG 414 C+ S +A +D T+ I+ + + S H V C+ +A+G D Sbjct: 554 CVSYSPNQKLLAVSLLDCTVKIFYVDTLKFFLSLYGHKLPVICMDISHDGALIATGSADR 613 Query: 413 MVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFDISMFK 255 V+IW GD ++ H D V L + + D + +D F+ Sbjct: 614 NVKIWGLDFGDCHKSLFAHDDSVMYLQFVPKSHLFFTAGKDHKIKQWDADKFE 666 Score = 31.6 bits (70), Expect = 2.2 Identities = 12/42 (28%), Positives = 25/42 (59%) Frame = -2 Query: 626 VGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAI 501 + +L GH I C+ +S ++V + S D++L +W+ R+ + Sbjct: 668 IQTLEGHHQEIWCLAVSPSGDYVVSSSHDKSLRLWERTREPL 709
>APAF_MOUSE (O88879) Apoptotic protease-activating factor 1 (Apaf-1)| Length = 1249 Score = 64.3 bits (155), Expect = 3e-10 Identities = 38/143 (26%), Positives = 69/143 (48%), Gaps = 3/143 (2%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLAR-QAIRSTCE 486 ++ + +G+ + + H + + C SS +++AT S D+ + IWD A + + + E Sbjct: 638 TLQVFKAETGEKLLDIKAHEDEVLCCAFSSDDSYIATCSADKKVKIWDSATGKLVHTYDE 697 Query: 485 HDEGVTCLAWLGSSRYV--ASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNS 312 H E V C + SS ++ A+G D +++WD + T GH + V S D Sbjct: 698 HSEQVNCCHFTNSSNHLLLATGSNDFFLKLWDLNQKECRNTMFGHTNSVNHCRFSPDDEL 757 Query: 311 IVSVSTDKSARVFDISMFK*EKS 243 + S S D + R++D+ KS Sbjct: 758 LASCSADGTLRLWDVRSANERKS 780 Score = 61.2 bits (147), Expect = 3e-09 Identities = 35/134 (26%), Positives = 66/134 (49%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCEH 483 ++ I+ + + +V S VGH ++ I ++ + + S D + +W+ H Sbjct: 984 AIKIIELPNNRVFSSGVGHKKAVRHIQFTADGKTLISSSEDSVIQVWNWQTGDYVFLQAH 1043 Query: 482 DEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVS 303 E V L SR + S DG V++W+ ++G + R F+ H+ V S A+S+D S Sbjct: 1044 QETVKDFRLLQDSRLL-SWSFDGTVKVWNVITGRIERDFTCHQGTVLSCAISSDATKFSS 1102 Query: 302 VSTDKSARVFDISM 261 S DK+A+++ + Sbjct: 1103 TSADKTAKIWSFDL 1116 Score = 44.7 bits (104), Expect = 3e-04 Identities = 28/118 (23%), Positives = 56/118 (47%), Gaps = 3/118 (2%) Frame = -2 Query: 608 HTNSIECIGISSRYNWVATGSIDRTLIIWDLAR-QAIRSTCEHDEGVTCLAWLGSSRYVA 432 HT+++ S +A+ D+TL ++ + + H++ V C A+ Y+A Sbjct: 614 HTDAVYHACFSQDGQRIASCGADKTLQVFKAETGEKLLDIKAHEDEVLCCAFSSDDSYIA 673 Query: 431 SGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIV--SVSTDKSARVFDIS 264 + D V+IWDS +G L T+ H + V + N ++ + S D +++D++ Sbjct: 674 TCSADKKVKIWDSATGKLVHTYDEHSEQVNCCHFTNSSNHLLLATGSNDFFLKLWDLN 731 Score = 35.8 bits (81), Expect = 0.12 Identities = 19/68 (27%), Positives = 36/68 (52%) Frame = -2 Query: 473 VTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVST 294 V+C YVA G DG ++I + + + + GH+ V+ + +ADG +++S S Sbjct: 964 VSCCCLSPHLEYVAFGDEDGAIKIIELPNNRVFSSGVGHKKAVRHIQFTADGKTLISSSE 1023 Query: 293 DKSARVFD 270 D +V++ Sbjct: 1024 DSVIQVWN 1031 Score = 35.0 bits (79), Expect = 0.20 Identities = 27/116 (23%), Positives = 52/116 (44%), Gaps = 10/116 (8%) Frame = -2 Query: 617 LVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCE----------HDEGVT 468 L GH + C S +ATG + + IW+++ + +C H VT Sbjct: 1123 LKGHNGCVRCSAFSLDGILLATGDDNGEIRIWNVSDGQLLHSCAPISVEEGTATHGGWVT 1182 Query: 467 CLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSV 300 + + S+ + S G ++ W+ +GD ++TF + ++ + VS D + V+V Sbjct: 1183 DVCFSPDSKTLVSA--GGYLKWWNVATGDSSQTFYTNGTNLKKIHVSPDFRTYVTV 1236
>GBLP_DICDI (P46800) Guanine nucleotide-binding protein beta subunit-like| protein Length = 329 Score = 64.3 bits (155), Expect = 3e-10 Identities = 40/131 (30%), Positives = 70/131 (53%), Gaps = 4/131 (3%) Frame = -2 Query: 635 GQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLAR-QAIRSTCEHDEGVTCLA 459 G+ SL GH++ ++ + IS + +GS D TL +WD+ + + R H + V +A Sbjct: 60 GKAHRSLKGHSHFVQDVVISHDGQFALSGSWDNTLRLWDITKGVSTRLFKGHTQDVMSVA 119 Query: 458 WLGSSRYVASGCIDGMVRIWDSLSGDLARTFSG---HRDVVQSLAVSADGNSIVSVSTDK 288 + +R + SG D +++W++L G+ T G H+D V + S + +IVS S D Sbjct: 120 FSSDNRQIISGSRDATIKVWNTL-GECKFTLEGPEAHQDWVSCIRFSPNTPTIVSGSWDN 178 Query: 287 SARVFDISMFK 255 +++DI FK Sbjct: 179 KVKIWDIKSFK 189 Score = 64.3 bits (155), Expect = 3e-10 Identities = 40/127 (31%), Positives = 62/127 (48%), Gaps = 8/127 (6%) Frame = -2 Query: 626 VGSLVGHTNSIECIGISSRY-NWVATGSIDRTLIIWDLAR-------QAIRSTCEHDEGV 471 VGSLVGH + I +S + + + S D+T+++W L +A RS H V Sbjct: 14 VGSLVGHNGFVTSIAVSPENPDTIISSSRDKTVMVWQLTPTDATSPGKAHRSLKGHSHFV 73 Query: 470 TCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTD 291 + ++ SG D +R+WD G R F GH V S+A S+D I+S S D Sbjct: 74 QDVVISHDGQFALSGSWDNTLRLWDITKGVSTRLFKGHTQDVMSVAFSSDNRQIISGSRD 133 Query: 290 KSARVFD 270 + +V++ Sbjct: 134 ATIKVWN 140 Score = 57.8 bits (138), Expect = 3e-08 Identities = 36/140 (25%), Positives = 65/140 (46%), Gaps = 4/140 (2%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCE- 486 ++ + I G GHT + + SS + +GS D T+ +W+ + + T E Sbjct: 93 TLRLWDITKGVSTRLFKGHTQDVMSVAFSSDNRQIISGSRDATIKVWNTLGEC-KFTLEG 151 Query: 485 ---HDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGN 315 H + V+C+ + ++ + SG D V+IWD S T + H V ++ +S DG+ Sbjct: 152 PEAHQDWVSCIRFSPNTPTIVSGSWDNKVKIWDIKSFKCNHTLTDHTGYVNTVTISPDGS 211 Query: 314 SIVSVSTDKSARVFDISMFK 255 S D A ++++S K Sbjct: 212 LCASGGKDTFACLWELSSGK 231 Score = 33.5 bits (75), Expect = 0.58 Identities = 36/149 (24%), Positives = 58/149 (38%), Gaps = 17/149 (11%) Frame = -2 Query: 659 VHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCEHD 480 V I I S + +L HT + + IS + A+G D +W+L+ E Sbjct: 180 VKIWDIKSFKCNHTLTDHTGYVNTVTISPDGSLCASGGKDTFACLWELSSGKPLYKLEAR 239 Query: 479 EGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDL---------ARTFSGHR--------D 351 + LA+ ++Y S D + IWD L+ + + F + Sbjct: 240 NTINALAF-SPNKYWLSAATDDKIIIWDLLTKQVLAEIVPEVKEQAFDSKKKKESKPKAP 298 Query: 350 VVQSLAVSADGNSIVSVSTDKSARVFDIS 264 SLA SADG+ + + D RV+ S Sbjct: 299 ACLSLAWSADGSVLYAGYNDGLIRVYKSS 327
>UTP13_YEAST (Q05946) U3 small nucleolar RNA-associated protein 13 (U3| snoRNA-associated protein 13) Length = 817 Score = 64.3 bits (155), Expect = 3e-10 Identities = 34/122 (27%), Positives = 62/122 (50%), Gaps = 1/122 (0%) Frame = -2 Query: 653 IVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCE-HDE 477 I ++ +G++ +L H + + +AT S D+T+ IW L ++ T E H Sbjct: 517 IWNLENGELEATLANHKRGLWDVSFCQYDKLLATSSGDKTVKIWSLDTFSVMKTLEGHTN 576 Query: 476 GVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVS 297 V +++ + + S DG+++IWD SG+ +T GH + + +L+ DG+ IVS Sbjct: 577 AVQRCSFINKQKQLISCGADGLIKIWDCSSGECLKTLDGHNNRLWALSTMNDGDMIVSAD 636 Query: 296 TD 291 D Sbjct: 637 AD 638 Score = 49.3 bits (116), Expect = 1e-05 Identities = 28/116 (24%), Positives = 53/116 (45%), Gaps = 1/116 (0%) Frame = -2 Query: 608 HTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRST-CEHDEGVTCLAWLGSSRYVA 432 H I + +S + AT S D+T IW+L + +T H G+ +++ + +A Sbjct: 490 HEKDINALSVSPNDSIFATASYDKTCKIWNLENGELEATLANHKRGLWDVSFCQYDKLLA 549 Query: 431 SGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFDIS 264 + D V+IW + + +T GH + VQ + ++S D +++D S Sbjct: 550 TSSGDKTVKIWSLDTFSVMKTLEGHTNAVQRCSFINKQKQLISCGADGLIKIWDCS 605 Score = 37.4 bits (85), Expect = 0.040 Identities = 22/90 (24%), Positives = 49/90 (54%), Gaps = 2/90 (2%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIE-CIGISSRYNWVATGSIDRTLIIWDLAR-QAIRSTC 489 +V I S+++ V+ +L GHTN+++ C I+ + ++ G+ D + IWD + + +++ Sbjct: 556 TVKIWSLDTFSVMKTLEGHTNAVQRCSFINKQKQLISCGA-DGLIKIWDCSSGECLKTLD 614 Query: 488 EHDEGVTCLAWLGSSRYVASGCIDGMVRIW 399 H+ + L+ + + S DG+ + W Sbjct: 615 GHNNRLWALSTMNDGDMIVSADADGVFQFW 644 Score = 35.4 bits (80), Expect = 0.15 Identities = 24/140 (17%), Positives = 59/140 (42%), Gaps = 16/140 (11%) Frame = -2 Query: 629 VVGSLVGHTNSIECIG----ISSRY-NWVATGSIDRTLIIWDLARQAIRSTCE------- 486 + +GH+ ++ +G +S Y ++ T S D T+ W + + + Sbjct: 426 IYAKYIGHSAAVTAVGLPNIVSKGYPEFLLTASNDLTIKKWIIPKPTASMDVQIIKVSEY 485 Query: 485 ----HDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADG 318 H++ + L+ + A+ D +IW+ +G+L T + H+ + ++ Sbjct: 486 TRHAHEKDINALSVSPNDSIFATASYDKTCKIWNLENGELEATLANHKRGLWDVSFCQYD 545 Query: 317 NSIVSVSTDKSARVFDISMF 258 + + S DK+ +++ + F Sbjct: 546 KLLATSSGDKTVKIWSLDTF 565 Score = 35.0 bits (79), Expect = 0.20 Identities = 28/113 (24%), Positives = 51/113 (45%), Gaps = 5/113 (4%) Frame = -2 Query: 653 IVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCE-HDE 477 I + +G+VV S+ + S + S +A G D ++I+ D+ I + + H Sbjct: 87 IFHLKTGKVVRSMKISSPSY-ILDADSTSTLLAVGGTDGSIIVVDIENGYITHSFKGHGG 145 Query: 476 GVTCLAWLGSSR----YVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAV 330 ++ L + G +ASG +GMV++WD + T H V+ L + Sbjct: 146 TISSLKFYGQLNSKIWLLASGDTNGMVKVWDLVKRKCLHTLQEHTSAVRGLDI 198
>WDR71_CHICK (Q5ZK69) WD-repeat protein 71| Length = 392 Score = 64.3 bits (155), Expect = 3e-10 Identities = 38/114 (33%), Positives = 55/114 (48%), Gaps = 1/114 (0%) Frame = -2 Query: 608 HTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCE-HDEGVTCLAWLGSSRYVA 432 H SI C+ ISS + S D T+ IW A IR E H V C + S V Sbjct: 91 HQKSITCLDISSGGGLGVSTSTDGTMKIWQAANGEIRRLLEGHVYDVNCCRFFPSGLVVL 150 Query: 431 SGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFD 270 SG +D ++IW + TF GH+ + A+ G +++S S D +AR++D Sbjct: 151 SGGMDAQLKIWSAEDASCVVTFKGHKGGILDTAIVDRGRNVLSCSRDGTARLWD 204
>GBLP_RAT (P63245) Guanine nucleotide-binding protein beta subunit 2-like 1| (Receptor of activated protein kinase C 1) (RACK1) (Receptor for activated C kinase) Length = 316 Score = 63.9 bits (154), Expect = 4e-10 Identities = 38/125 (30%), Positives = 64/125 (51%), Gaps = 7/125 (5%) Frame = -2 Query: 623 GSLVGHTNSIECIGISSRY-NWVATGSIDRTLIIWDLARQAI------RSTCEHDEGVTC 465 G+L GH + I + ++ + + + S D+T+I+W L R R+ H V+ Sbjct: 8 GTLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSD 67 Query: 464 LAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKS 285 + ++ SG DG +R+WD +G R F GH V S+A S+D IVS S DK+ Sbjct: 68 VVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKT 127 Query: 284 ARVFD 270 ++++ Sbjct: 128 IKLWN 132 Score = 54.3 bits (129), Expect = 3e-07 Identities = 32/138 (23%), Positives = 67/138 (48%), Gaps = 5/138 (3%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWD---LARQAIRST 492 ++ + + +G VGHT + + SS + +GS D+T+ +W+ + + ++ Sbjct: 85 TLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLWNTLGVCKYTVQDE 144 Query: 491 CEHDEGVTCLAWL--GSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADG 318 H E V+C+ + S+ + S D +V++W+ + L GH + ++ VS DG Sbjct: 145 -SHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHIGHTGYLNTVTVSPDG 203 Query: 317 NSIVSVSTDKSARVFDIS 264 + S D A ++D++ Sbjct: 204 SLCASGGKDGQAMLWDLN 221 Score = 47.8 bits (112), Expect = 3e-05 Identities = 38/134 (28%), Positives = 66/134 (49%), Gaps = 5/134 (3%) Frame = -2 Query: 641 NSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLAR-QAIRSTCEHDEGVTC 465 N G +L GH++ + + ISS + +GS D TL +WDL R H + V Sbjct: 50 NYGIPQRALRGHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLS 109 Query: 464 LAWLGSSRYVASGCIDGMVRIWDSLSGDLARTF--SGHRDVVQSLAVSADGNS--IVSVS 297 +A+ +R + SG D +++W++L G T H + V + S + ++ IVS Sbjct: 110 VAFSSDNRQIVSGSRDKTIKLWNTL-GVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCG 168 Query: 296 TDKSARVFDISMFK 255 DK +V++++ K Sbjct: 169 WDKLVKVWNLANCK 182 Score = 39.7 bits (91), Expect = 0.008 Identities = 31/127 (24%), Positives = 55/127 (43%), Gaps = 9/127 (7%) Frame = -2 Query: 614 VGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCEHDEGVTCLAWLGSSRYV 435 +GHT + + +S + A+G D ++WDL T + + + L + +RY Sbjct: 188 IGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGGDIINALCF-SPNRYW 246 Query: 434 ASGCIDGMVRIWD--------SLSGDLARTFS-GHRDVVQSLAVSADGNSIVSVSTDKSA 282 ++IWD L ++ T S SLA SADG ++ + TD Sbjct: 247 LCAATGPSIKIWDLEGKIIVDELKQEVISTSSKAEPPQCTSLAWSADGQTLFAGYTDNLV 306 Query: 281 RVFDISM 261 RV+ +++ Sbjct: 307 RVWQVTI 313 Score = 33.5 bits (75), Expect = 0.58 Identities = 25/101 (24%), Positives = 43/101 (42%), Gaps = 10/101 (9%) Frame = -2 Query: 656 HIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLA--------RQAI 501 H+ +++ G ++ +L C + + ATG ++ IWDL +Q + Sbjct: 225 HLYTLDGGDIINAL--------CFSPNRYWLCAATGP---SIKIWDLEGKIIVDELKQEV 273 Query: 500 RSTCEHDEGVTC--LAWLGSSRYVASGCIDGMVRIWDSLSG 384 ST E C LAW + + +G D +VR+W G Sbjct: 274 ISTSSKAEPPQCTSLAWSADGQTLFAGYTDNLVRVWQVTIG 314
>GBLP_PIG (P63246) Guanine nucleotide-binding protein beta subunit 2-like 1| (Receptor of activated protein kinase C 1) (RACK1) (Receptor for activated C kinase) Length = 316 Score = 63.9 bits (154), Expect = 4e-10 Identities = 38/125 (30%), Positives = 64/125 (51%), Gaps = 7/125 (5%) Frame = -2 Query: 623 GSLVGHTNSIECIGISSRY-NWVATGSIDRTLIIWDLARQAI------RSTCEHDEGVTC 465 G+L GH + I + ++ + + + S D+T+I+W L R R+ H V+ Sbjct: 8 GTLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSD 67 Query: 464 LAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKS 285 + ++ SG DG +R+WD +G R F GH V S+A S+D IVS S DK+ Sbjct: 68 VVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKT 127 Query: 284 ARVFD 270 ++++ Sbjct: 128 IKLWN 132 Score = 54.3 bits (129), Expect = 3e-07 Identities = 32/138 (23%), Positives = 67/138 (48%), Gaps = 5/138 (3%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWD---LARQAIRST 492 ++ + + +G VGHT + + SS + +GS D+T+ +W+ + + ++ Sbjct: 85 TLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLWNTLGVCKYTVQDE 144 Query: 491 CEHDEGVTCLAWL--GSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADG 318 H E V+C+ + S+ + S D +V++W+ + L GH + ++ VS DG Sbjct: 145 -SHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHIGHTGYLNTVTVSPDG 203 Query: 317 NSIVSVSTDKSARVFDIS 264 + S D A ++D++ Sbjct: 204 SLCASGGKDGQAMLWDLN 221 Score = 47.8 bits (112), Expect = 3e-05 Identities = 38/134 (28%), Positives = 66/134 (49%), Gaps = 5/134 (3%) Frame = -2 Query: 641 NSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLAR-QAIRSTCEHDEGVTC 465 N G +L GH++ + + ISS + +GS D TL +WDL R H + V Sbjct: 50 NYGIPQRALRGHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLS 109 Query: 464 LAWLGSSRYVASGCIDGMVRIWDSLSGDLARTF--SGHRDVVQSLAVSADGNS--IVSVS 297 +A+ +R + SG D +++W++L G T H + V + S + ++ IVS Sbjct: 110 VAFSSDNRQIVSGSRDKTIKLWNTL-GVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCG 168 Query: 296 TDKSARVFDISMFK 255 DK +V++++ K Sbjct: 169 WDKLVKVWNLANCK 182 Score = 39.7 bits (91), Expect = 0.008 Identities = 31/127 (24%), Positives = 55/127 (43%), Gaps = 9/127 (7%) Frame = -2 Query: 614 VGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCEHDEGVTCLAWLGSSRYV 435 +GHT + + +S + A+G D ++WDL T + + + L + +RY Sbjct: 188 IGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGGDIINALCF-SPNRYW 246 Query: 434 ASGCIDGMVRIWD--------SLSGDLARTFS-GHRDVVQSLAVSADGNSIVSVSTDKSA 282 ++IWD L ++ T S SLA SADG ++ + TD Sbjct: 247 LCAATGPSIKIWDLEGKIIVDELKQEVISTSSKAEPPQCTSLAWSADGQTLFAGYTDNLV 306 Query: 281 RVFDISM 261 RV+ +++ Sbjct: 307 RVWQVTI 313 Score = 33.5 bits (75), Expect = 0.58 Identities = 25/101 (24%), Positives = 43/101 (42%), Gaps = 10/101 (9%) Frame = -2 Query: 656 HIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLA--------RQAI 501 H+ +++ G ++ +L C + + ATG ++ IWDL +Q + Sbjct: 225 HLYTLDGGDIINAL--------CFSPNRYWLCAATGP---SIKIWDLEGKIIVDELKQEV 273 Query: 500 RSTCEHDEGVTC--LAWLGSSRYVASGCIDGMVRIWDSLSG 384 ST E C LAW + + +G D +VR+W G Sbjct: 274 ISTSSKAEPPQCTSLAWSADGQTLFAGYTDNLVRVWQVTIG 314
>GBLP_MOUSE (P68040) Guanine nucleotide-binding protein beta subunit 2-like 1| (Receptor of activated protein kinase C 1) (RACK1) (Receptor for activated C kinase) (p205) (12-3) Length = 316 Score = 63.9 bits (154), Expect = 4e-10 Identities = 38/125 (30%), Positives = 64/125 (51%), Gaps = 7/125 (5%) Frame = -2 Query: 623 GSLVGHTNSIECIGISSRY-NWVATGSIDRTLIIWDLARQAI------RSTCEHDEGVTC 465 G+L GH + I + ++ + + + S D+T+I+W L R R+ H V+ Sbjct: 8 GTLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSD 67 Query: 464 LAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKS 285 + ++ SG DG +R+WD +G R F GH V S+A S+D IVS S DK+ Sbjct: 68 VVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKT 127 Query: 284 ARVFD 270 ++++ Sbjct: 128 IKLWN 132 Score = 54.3 bits (129), Expect = 3e-07 Identities = 32/138 (23%), Positives = 67/138 (48%), Gaps = 5/138 (3%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWD---LARQAIRST 492 ++ + + +G VGHT + + SS + +GS D+T+ +W+ + + ++ Sbjct: 85 TLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLWNTLGVCKYTVQDE 144 Query: 491 CEHDEGVTCLAWL--GSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADG 318 H E V+C+ + S+ + S D +V++W+ + L GH + ++ VS DG Sbjct: 145 -SHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHIGHTGYLNTVTVSPDG 203 Query: 317 NSIVSVSTDKSARVFDIS 264 + S D A ++D++ Sbjct: 204 SLCASGGKDGQAMLWDLN 221 Score = 47.8 bits (112), Expect = 3e-05 Identities = 38/134 (28%), Positives = 66/134 (49%), Gaps = 5/134 (3%) Frame = -2 Query: 641 NSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLAR-QAIRSTCEHDEGVTC 465 N G +L GH++ + + ISS + +GS D TL +WDL R H + V Sbjct: 50 NYGIPQRALRGHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLS 109 Query: 464 LAWLGSSRYVASGCIDGMVRIWDSLSGDLARTF--SGHRDVVQSLAVSADGNS--IVSVS 297 +A+ +R + SG D +++W++L G T H + V + S + ++ IVS Sbjct: 110 VAFSSDNRQIVSGSRDKTIKLWNTL-GVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCG 168 Query: 296 TDKSARVFDISMFK 255 DK +V++++ K Sbjct: 169 WDKLVKVWNLANCK 182 Score = 39.7 bits (91), Expect = 0.008 Identities = 31/127 (24%), Positives = 55/127 (43%), Gaps = 9/127 (7%) Frame = -2 Query: 614 VGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCEHDEGVTCLAWLGSSRYV 435 +GHT + + +S + A+G D ++WDL T + + + L + +RY Sbjct: 188 IGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGGDIINALCF-SPNRYW 246 Query: 434 ASGCIDGMVRIWD--------SLSGDLARTFS-GHRDVVQSLAVSADGNSIVSVSTDKSA 282 ++IWD L ++ T S SLA SADG ++ + TD Sbjct: 247 LCAATGPSIKIWDLEGKIIVDELKQEVISTSSKAEPPQCTSLAWSADGQTLFAGYTDNLV 306 Query: 281 RVFDISM 261 RV+ +++ Sbjct: 307 RVWQVTI 313 Score = 33.5 bits (75), Expect = 0.58 Identities = 25/101 (24%), Positives = 43/101 (42%), Gaps = 10/101 (9%) Frame = -2 Query: 656 HIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLA--------RQAI 501 H+ +++ G ++ +L C + + ATG ++ IWDL +Q + Sbjct: 225 HLYTLDGGDIINAL--------CFSPNRYWLCAATGP---SIKIWDLEGKIIVDELKQEV 273 Query: 500 RSTCEHDEGVTC--LAWLGSSRYVASGCIDGMVRIWDSLSG 384 ST E C LAW + + +G D +VR+W G Sbjct: 274 ISTSSKAEPPQCTSLAWSADGQTLFAGYTDNLVRVWQVTIG 314
>GBLP_MACFA (Q4R7Y4) Guanine nucleotide-binding protein beta subunit 2-like 1| Length = 316 Score = 63.9 bits (154), Expect = 4e-10 Identities = 38/125 (30%), Positives = 64/125 (51%), Gaps = 7/125 (5%) Frame = -2 Query: 623 GSLVGHTNSIECIGISSRY-NWVATGSIDRTLIIWDLARQAI------RSTCEHDEGVTC 465 G+L GH + I + ++ + + + S D+T+I+W L R R+ H V+ Sbjct: 8 GTLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSD 67 Query: 464 LAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKS 285 + ++ SG DG +R+WD +G R F GH V S+A S+D IVS S DK+ Sbjct: 68 VVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKT 127 Query: 284 ARVFD 270 ++++ Sbjct: 128 IKLWN 132 Score = 54.3 bits (129), Expect = 3e-07 Identities = 32/138 (23%), Positives = 67/138 (48%), Gaps = 5/138 (3%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWD---LARQAIRST 492 ++ + + +G VGHT + + SS + +GS D+T+ +W+ + + ++ Sbjct: 85 TLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLWNTLGVCKYTVQDE 144 Query: 491 CEHDEGVTCLAWL--GSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADG 318 H E V+C+ + S+ + S D +V++W+ + L GH + ++ VS DG Sbjct: 145 -SHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHIGHTGYLNTVTVSPDG 203 Query: 317 NSIVSVSTDKSARVFDIS 264 + S D A ++D++ Sbjct: 204 SLCASGGKDGQAMLWDLN 221 Score = 47.8 bits (112), Expect = 3e-05 Identities = 38/134 (28%), Positives = 66/134 (49%), Gaps = 5/134 (3%) Frame = -2 Query: 641 NSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLAR-QAIRSTCEHDEGVTC 465 N G +L GH++ + + ISS + +GS D TL +WDL R H + V Sbjct: 50 NYGIPQRALRGHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLS 109 Query: 464 LAWLGSSRYVASGCIDGMVRIWDSLSGDLARTF--SGHRDVVQSLAVSADGNS--IVSVS 297 +A+ +R + SG D +++W++L G T H + V + S + ++ IVS Sbjct: 110 VAFSSDNRQIVSGSRDKTIKLWNTL-GVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCG 168 Query: 296 TDKSARVFDISMFK 255 DK +V++++ K Sbjct: 169 WDKLVKVWNLANCK 182 Score = 39.7 bits (91), Expect = 0.008 Identities = 31/127 (24%), Positives = 55/127 (43%), Gaps = 9/127 (7%) Frame = -2 Query: 614 VGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCEHDEGVTCLAWLGSSRYV 435 +GHT + + +S + A+G D ++WDL T + + + L + +RY Sbjct: 188 IGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGGDIINALCF-SPNRYW 246 Query: 434 ASGCIDGMVRIWD--------SLSGDLARTFS-GHRDVVQSLAVSADGNSIVSVSTDKSA 282 ++IWD L ++ T S SLA SADG ++ + TD Sbjct: 247 LCAATGPSIKIWDLEGKIIVDELKQEVISTSSKAEPPQCTSLAWSADGQTLFAGYTDNLV 306 Query: 281 RVFDISM 261 RV+ +++ Sbjct: 307 RVWQVTI 313 Score = 33.5 bits (75), Expect = 0.58 Identities = 25/101 (24%), Positives = 43/101 (42%), Gaps = 10/101 (9%) Frame = -2 Query: 656 HIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLA--------RQAI 501 H+ +++ G ++ +L C + + ATG ++ IWDL +Q + Sbjct: 225 HLYTLDGGDIINAL--------CFSPNRYWLCAATGP---SIKIWDLEGKIIVDELKQEV 273 Query: 500 RSTCEHDEGVTC--LAWLGSSRYVASGCIDGMVRIWDSLSG 384 ST E C LAW + + +G D +VR+W G Sbjct: 274 ISTSSKAEPPQCTSLAWSADGQTLFAGYTDNLVRVWQVTIG 314
>GBLP_HUMAN (P63244) Guanine nucleotide-binding protein beta subunit 2-like 1| (Guanine nucleotide-binding protein beta subunit-like protein 12.3) (Receptor of activated protein kinase C 1) (RACK1) (Receptor for activated C kinase) Length = 316 Score = 63.9 bits (154), Expect = 4e-10 Identities = 38/125 (30%), Positives = 64/125 (51%), Gaps = 7/125 (5%) Frame = -2 Query: 623 GSLVGHTNSIECIGISSRY-NWVATGSIDRTLIIWDLARQAI------RSTCEHDEGVTC 465 G+L GH + I + ++ + + + S D+T+I+W L R R+ H V+ Sbjct: 8 GTLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSD 67 Query: 464 LAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKS 285 + ++ SG DG +R+WD +G R F GH V S+A S+D IVS S DK+ Sbjct: 68 VVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKT 127 Query: 284 ARVFD 270 ++++ Sbjct: 128 IKLWN 132 Score = 54.3 bits (129), Expect = 3e-07 Identities = 32/138 (23%), Positives = 67/138 (48%), Gaps = 5/138 (3%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWD---LARQAIRST 492 ++ + + +G VGHT + + SS + +GS D+T+ +W+ + + ++ Sbjct: 85 TLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLWNTLGVCKYTVQDE 144 Query: 491 CEHDEGVTCLAWL--GSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADG 318 H E V+C+ + S+ + S D +V++W+ + L GH + ++ VS DG Sbjct: 145 -SHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHIGHTGYLNTVTVSPDG 203 Query: 317 NSIVSVSTDKSARVFDIS 264 + S D A ++D++ Sbjct: 204 SLCASGGKDGQAMLWDLN 221 Score = 47.8 bits (112), Expect = 3e-05 Identities = 38/134 (28%), Positives = 66/134 (49%), Gaps = 5/134 (3%) Frame = -2 Query: 641 NSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLAR-QAIRSTCEHDEGVTC 465 N G +L GH++ + + ISS + +GS D TL +WDL R H + V Sbjct: 50 NYGIPQRALRGHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLS 109 Query: 464 LAWLGSSRYVASGCIDGMVRIWDSLSGDLARTF--SGHRDVVQSLAVSADGNS--IVSVS 297 +A+ +R + SG D +++W++L G T H + V + S + ++ IVS Sbjct: 110 VAFSSDNRQIVSGSRDKTIKLWNTL-GVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCG 168 Query: 296 TDKSARVFDISMFK 255 DK +V++++ K Sbjct: 169 WDKLVKVWNLANCK 182 Score = 39.7 bits (91), Expect = 0.008 Identities = 31/127 (24%), Positives = 55/127 (43%), Gaps = 9/127 (7%) Frame = -2 Query: 614 VGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCEHDEGVTCLAWLGSSRYV 435 +GHT + + +S + A+G D ++WDL T + + + L + +RY Sbjct: 188 IGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGGDIINALCF-SPNRYW 246 Query: 434 ASGCIDGMVRIWD--------SLSGDLARTFS-GHRDVVQSLAVSADGNSIVSVSTDKSA 282 ++IWD L ++ T S SLA SADG ++ + TD Sbjct: 247 LCAATGPSIKIWDLEGKIIVDELKQEVISTSSKAEPPQCTSLAWSADGQTLFAGYTDNLV 306 Query: 281 RVFDISM 261 RV+ +++ Sbjct: 307 RVWQVTI 313 Score = 33.5 bits (75), Expect = 0.58 Identities = 25/101 (24%), Positives = 43/101 (42%), Gaps = 10/101 (9%) Frame = -2 Query: 656 HIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLA--------RQAI 501 H+ +++ G ++ +L C + + ATG ++ IWDL +Q + Sbjct: 225 HLYTLDGGDIINAL--------CFSPNRYWLCAATGP---SIKIWDLEGKIIVDELKQEV 273 Query: 500 RSTCEHDEGVTC--LAWLGSSRYVASGCIDGMVRIWDSLSG 384 ST E C LAW + + +G D +VR+W G Sbjct: 274 ISTSSKAEPPQCTSLAWSADGQTLFAGYTDNLVRVWQVTIG 314
>GBLP_BOVIN (P63243) Guanine nucleotide-binding protein beta subunit 2-like 1| (Receptor of activated protein kinase C 1) (RACK1) (Receptor for activated C kinase) Length = 316 Score = 63.9 bits (154), Expect = 4e-10 Identities = 38/125 (30%), Positives = 64/125 (51%), Gaps = 7/125 (5%) Frame = -2 Query: 623 GSLVGHTNSIECIGISSRY-NWVATGSIDRTLIIWDLARQAI------RSTCEHDEGVTC 465 G+L GH + I + ++ + + + S D+T+I+W L R R+ H V+ Sbjct: 8 GTLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSD 67 Query: 464 LAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKS 285 + ++ SG DG +R+WD +G R F GH V S+A S+D IVS S DK+ Sbjct: 68 VVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKT 127 Query: 284 ARVFD 270 ++++ Sbjct: 128 IKLWN 132 Score = 54.3 bits (129), Expect = 3e-07 Identities = 32/138 (23%), Positives = 67/138 (48%), Gaps = 5/138 (3%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWD---LARQAIRST 492 ++ + + +G VGHT + + SS + +GS D+T+ +W+ + + ++ Sbjct: 85 TLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLWNTLGVCKYTVQDE 144 Query: 491 CEHDEGVTCLAWL--GSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADG 318 H E V+C+ + S+ + S D +V++W+ + L GH + ++ VS DG Sbjct: 145 -SHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHIGHTGYLNTVTVSPDG 203 Query: 317 NSIVSVSTDKSARVFDIS 264 + S D A ++D++ Sbjct: 204 SLCASGGKDGQAMLWDLN 221 Score = 47.8 bits (112), Expect = 3e-05 Identities = 38/134 (28%), Positives = 66/134 (49%), Gaps = 5/134 (3%) Frame = -2 Query: 641 NSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLAR-QAIRSTCEHDEGVTC 465 N G +L GH++ + + ISS + +GS D TL +WDL R H + V Sbjct: 50 NYGIPQRALRGHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLS 109 Query: 464 LAWLGSSRYVASGCIDGMVRIWDSLSGDLARTF--SGHRDVVQSLAVSADGNS--IVSVS 297 +A+ +R + SG D +++W++L G T H + V + S + ++ IVS Sbjct: 110 VAFSSDNRQIVSGSRDKTIKLWNTL-GVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCG 168 Query: 296 TDKSARVFDISMFK 255 DK +V++++ K Sbjct: 169 WDKLVKVWNLANCK 182 Score = 39.7 bits (91), Expect = 0.008 Identities = 31/127 (24%), Positives = 55/127 (43%), Gaps = 9/127 (7%) Frame = -2 Query: 614 VGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCEHDEGVTCLAWLGSSRYV 435 +GHT + + +S + A+G D ++WDL T + + + L + +RY Sbjct: 188 IGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGGDIINALCF-SPNRYW 246 Query: 434 ASGCIDGMVRIWD--------SLSGDLARTFS-GHRDVVQSLAVSADGNSIVSVSTDKSA 282 ++IWD L ++ T S SLA SADG ++ + TD Sbjct: 247 LCAATGPSIKIWDLEGKIIVDELKQEVISTSSKAEPPQCTSLAWSADGQTLFAGYTDNLV 306 Query: 281 RVFDISM 261 RV+ +++ Sbjct: 307 RVWQVTI 313 Score = 33.5 bits (75), Expect = 0.58 Identities = 25/101 (24%), Positives = 43/101 (42%), Gaps = 10/101 (9%) Frame = -2 Query: 656 HIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLA--------RQAI 501 H+ +++ G ++ +L C + + ATG ++ IWDL +Q + Sbjct: 225 HLYTLDGGDIINAL--------CFSPNRYWLCAATGP---SIKIWDLEGKIIVDELKQEV 273 Query: 500 RSTCEHDEGVTC--LAWLGSSRYVASGCIDGMVRIWDSLSG 384 ST E C LAW + + +G D +VR+W G Sbjct: 274 ISTSSKAEPPQCTSLAWSADGQTLFAGYTDNLVRVWQVTIG 314
>KMHA_DICDI (P42527) Myosin heavy chain kinase A (EC 2.7.11.7) (MHCK A)| Length = 1146 Score = 63.9 bits (154), Expect = 4e-10 Identities = 41/136 (30%), Positives = 73/136 (53%), Gaps = 2/136 (1%) Frame = -2 Query: 659 VHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCE-- 486 VHI+ + + + +LVGHT + C+ + +Y + + S D+T+ +WDL+ + E Sbjct: 936 VHIIRSGNTKCIETLVGHTGEVNCVVANEKY--LFSCSYDKTIKVWDLSTFKEIKSFEGV 993 Query: 485 HDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIV 306 H + + LA G RY+ SG D ++ +WD+ + + GH D V SL +A + + Sbjct: 994 HTKYIKTLALSG--RYLFSGGNDQIIYVWDTETLSMLFNMQGHEDWVLSLHCTA--SYLF 1049 Query: 305 SVSTDKSARVFDISMF 258 S S D +++D+S F Sbjct: 1050 STSKDNVIKIWDLSNF 1065 Score = 41.2 bits (95), Expect = 0.003 Identities = 24/90 (26%), Positives = 44/90 (48%), Gaps = 2/90 (2%) Frame = -2 Query: 659 VHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTC--E 486 + I +++ + +L GH NS+ + RY + +GS D ++ +WDL T Sbjct: 1057 IKIWDLSNFSCIDTLKGHWNSVSSCVVKDRY--LYSGSEDNSIKVWDLDTLECVYTIPKS 1114 Query: 485 HDEGVTCLAWLGSSRYVASGCIDGMVRIWD 396 H GV CL + + + S DG +++W+ Sbjct: 1115 HSLGVKCL--MVFNNQIISAAFDGSIKVWE 1142 Score = 30.8 bits (68), Expect = 3.8 Identities = 25/86 (29%), Positives = 40/86 (46%), Gaps = 2/86 (2%) Frame = -2 Query: 479 EGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLA--RTFSGHRDVVQSLAVSADGNSIV 306 E + C +S Y+ + D +++ SG+ T GH V V A+ + Sbjct: 916 ESIAC-----NSNYIFTSSPDNTIKVHIIRSGNTKCIETLVGHTGEVN--CVVANEKYLF 968 Query: 305 SVSTDKSARVFDISMFK*EKS*QQQH 228 S S DK+ +V+D+S FK KS + H Sbjct: 969 SCSYDKTIKVWDLSTFKEIKSFEGVH 994
>GBLP_CHICK (P63247) Guanine nucleotide-binding protein beta subunit 2-like 1| (Guanine nucleotide-binding protein beta subunit-like protein 12.3) (Receptor of activated protein kinase C 1) (RACK1) (Receptor for activated C kinase) Length = 317 Score = 63.9 bits (154), Expect = 4e-10 Identities = 38/125 (30%), Positives = 64/125 (51%), Gaps = 7/125 (5%) Frame = -2 Query: 623 GSLVGHTNSIECIGISSRY-NWVATGSIDRTLIIWDLARQAI------RSTCEHDEGVTC 465 G+L GH + I + ++ + + + S D+T+I+W L R R+ H V+ Sbjct: 9 GTLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSD 68 Query: 464 LAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKS 285 + ++ SG DG +R+WD +G R F GH V S+A S+D IVS S DK+ Sbjct: 69 VVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKT 128 Query: 284 ARVFD 270 ++++ Sbjct: 129 IKLWN 133 Score = 54.3 bits (129), Expect = 3e-07 Identities = 32/138 (23%), Positives = 67/138 (48%), Gaps = 5/138 (3%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWD---LARQAIRST 492 ++ + + +G VGHT + + SS + +GS D+T+ +W+ + + ++ Sbjct: 86 TLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLWNTLGVCKYTVQDE 145 Query: 491 CEHDEGVTCLAWL--GSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADG 318 H E V+C+ + S+ + S D +V++W+ + L GH + ++ VS DG Sbjct: 146 -SHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHIGHTGYLNTVTVSPDG 204 Query: 317 NSIVSVSTDKSARVFDIS 264 + S D A ++D++ Sbjct: 205 SLCASGGKDGQAMLWDLN 222 Score = 47.8 bits (112), Expect = 3e-05 Identities = 38/134 (28%), Positives = 66/134 (49%), Gaps = 5/134 (3%) Frame = -2 Query: 641 NSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLAR-QAIRSTCEHDEGVTC 465 N G +L GH++ + + ISS + +GS D TL +WDL R H + V Sbjct: 51 NYGIPQRALRGHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLS 110 Query: 464 LAWLGSSRYVASGCIDGMVRIWDSLSGDLARTF--SGHRDVVQSLAVSADGNS--IVSVS 297 +A+ +R + SG D +++W++L G T H + V + S + ++ IVS Sbjct: 111 VAFSSDNRQIVSGSRDKTIKLWNTL-GVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCG 169 Query: 296 TDKSARVFDISMFK 255 DK +V++++ K Sbjct: 170 WDKLVKVWNLANCK 183 Score = 39.7 bits (91), Expect = 0.008 Identities = 31/127 (24%), Positives = 55/127 (43%), Gaps = 9/127 (7%) Frame = -2 Query: 614 VGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCEHDEGVTCLAWLGSSRYV 435 +GHT + + +S + A+G D ++WDL T + + + L + +RY Sbjct: 189 IGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGGDIINALCF-SPNRYW 247 Query: 434 ASGCIDGMVRIWD--------SLSGDLARTFS-GHRDVVQSLAVSADGNSIVSVSTDKSA 282 ++IWD L ++ T S SLA SADG ++ + TD Sbjct: 248 LCAATGPSIKIWDLEGKIIVDELKQEVISTSSKAEPPQCTSLAWSADGQTLFAGYTDNLV 307 Query: 281 RVFDISM 261 RV+ +++ Sbjct: 308 RVWQVTI 314 Score = 33.5 bits (75), Expect = 0.58 Identities = 25/101 (24%), Positives = 43/101 (42%), Gaps = 10/101 (9%) Frame = -2 Query: 656 HIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLA--------RQAI 501 H+ +++ G ++ +L C + + ATG ++ IWDL +Q + Sbjct: 226 HLYTLDGGDIINAL--------CFSPNRYWLCAATGP---SIKIWDLEGKIIVDELKQEV 274 Query: 500 RSTCEHDEGVTC--LAWLGSSRYVASGCIDGMVRIWDSLSG 384 ST E C LAW + + +G D +VR+W G Sbjct: 275 ISTSSKAEPPQCTSLAWSADGQTLFAGYTDNLVRVWQVTIG 315
>GBLP_DROME (O18640) Guanine nucleotide-binding protein beta subunit-like| protein (Receptor of activated protein kinase C homolog) Length = 318 Score = 63.5 bits (153), Expect = 5e-10 Identities = 39/129 (30%), Positives = 63/129 (48%), Gaps = 8/129 (6%) Frame = -2 Query: 632 QVVGSLVGHTNSIECIGISSRY-NWVATGSIDRTLIIWDLARQAI-------RSTCEHDE 477 Q+ G+L+GH + I + + + + + S D+TLI+W L R + H Sbjct: 6 QLRGTLIGHNGWVTQIATNPKDPDTIISASRDKTLIVWKLTRDEDTNYGYPQKRLYGHSH 65 Query: 476 GVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVS 297 ++ + Y SG D +R+WD +G R F GH V S+A SAD IVS S Sbjct: 66 FISDVVLSSDGNYALSGSWDQTLRLWDLAAGKTTRRFEGHTKDVLSVAFSADNRQIVSGS 125 Query: 296 TDKSARVFD 270 DK+ ++++ Sbjct: 126 RDKTIKLWN 134 Score = 56.6 bits (135), Expect = 6e-08 Identities = 39/133 (29%), Positives = 70/133 (52%), Gaps = 4/133 (3%) Frame = -2 Query: 641 NSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLAR-QAIRSTCEHDEGVTC 465 N G L GH++ I + +SS N+ +GS D+TL +WDLA + R H + V Sbjct: 52 NYGYPQKRLYGHSHFISDVVLSSDGNYALSGSWDQTLRLWDLAAGKTTRRFEGHTKDVLS 111 Query: 464 LAWLGSSRYVASGCIDGMVRIWDSLSG-DLARTFSGHRDVVQSLAVSADGNS--IVSVST 294 +A+ +R + SG D +++W++L+ GH D V + S + ++ IVS Sbjct: 112 VAFSADNRQIVSGSRDKTIKLWNTLAECKFTIQEDGHTDWVSCVRFSPNHSNPIIVSCGW 171 Query: 293 DKSARVFDISMFK 255 D++ +V++++ K Sbjct: 172 DRTVKVWNLANCK 184 Score = 50.1 bits (118), Expect = 6e-06 Identities = 30/137 (21%), Positives = 65/137 (47%), Gaps = 4/137 (2%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCE- 486 ++ + + +G+ GHT + + S+ + +GS D+T+ +W+ + + E Sbjct: 87 TLRLWDLAAGKTTRRFEGHTKDVLSVAFSADNRQIVSGSRDKTIKLWNTLAECKFTIQED 146 Query: 485 -HDEGVTCLAWLG--SSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGN 315 H + V+C+ + S+ + S D V++W+ + L GH + ++ VS DG+ Sbjct: 147 GHTDWVSCVRFSPNHSNPIIVSCGWDRTVKVWNLANCKLKNNHHGHNGYLNTVTVSPDGS 206 Query: 314 SIVSVSTDKSARVFDIS 264 S D A ++D++ Sbjct: 207 LCTSGGKDSKALLWDLN 223 Score = 37.7 bits (86), Expect = 0.031 Identities = 28/126 (22%), Positives = 53/126 (42%), Gaps = 9/126 (7%) Frame = -2 Query: 611 GHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCEHDEGVTCLAWLGSSRYVA 432 GH + + +S + +G D ++WDL T EH++ + L + +RY Sbjct: 191 GHNGYLNTVTVSPDGSLCTSGGKDSKALLWDLNDGKNLYTLEHNDIINALCF-SPNRYWL 249 Query: 431 SGCIDGMVRIWDSLSGD---------LARTFSGHRDVVQSLAVSADGNSIVSVSTDKSAR 279 ++IWD ++ T + SLA S DG ++ + +D + R Sbjct: 250 CVAYGPSIKIWDLACKKTVEELRPEVVSPTSKADQPQCLSLAWSTDGQTLFAGYSDNTIR 309 Query: 278 VFDISM 261 V+ +S+ Sbjct: 310 VWQVSV 315
>COPB2_CAEEL (Q20168) Probable coatomer subunit beta' (Beta'-coat protein)| (Beta'-COP) Length = 1000 Score = 63.5 bits (153), Expect = 5e-10 Identities = 38/128 (29%), Positives = 65/128 (50%), Gaps = 4/128 (3%) Frame = -2 Query: 620 SLVGHTNSIECIGISSR-YNWVATGSIDRTLIIWDLARQAIRSTCE-HDEGVTCLAWL-- 453 S GHT+ + I I+ + N AT S+D+T+ +W T E H++GV C+ + Sbjct: 137 SFEGHTHYVMQIAINPKDNNTFATASLDKTVKVWQFGSNVPNFTLEGHEKGVNCVDYYHG 196 Query: 452 GSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVF 273 G Y+ SG D +V+IWD + +T GH V S+ + I++ S D + R++ Sbjct: 197 GEKPYIISGADDHLVKIWDYQNKTCVQTLDGHAQNVSSVCFHPELPLIITGSEDSTVRLW 256 Query: 272 DISMFK*E 249 + ++ E Sbjct: 257 HANTYRQE 264 Score = 38.1 bits (87), Expect = 0.024 Identities = 23/117 (19%), Positives = 53/117 (45%), Gaps = 1/117 (0%) Frame = -2 Query: 617 LVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCE-HDEGVTCLAWLGSSR 441 L+ ++ ++C+ + W+ + + IW+ Q + + E D V ++ Sbjct: 11 LLARSDRVKCVDLHPVETWLLAALYNGNVHIWNYETQTLVKSFEVCDVPVRAAKFVPRKS 70 Query: 440 YVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFD 270 +V +G D +R+++ + + F H D ++SL V ++S S D +++D Sbjct: 71 WVVTGSDDMHIRVFNYNTLERVHQFEAHSDYLRSLVVHPTLPYVISSSDDMLVKMWD 127
>GBB1_PONPY (Q5R5W8) Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta| subunit 1 (Transducin beta chain 1) Length = 339 Score = 63.5 bits (153), Expect = 5e-10 Identities = 39/134 (29%), Positives = 62/134 (46%), Gaps = 3/134 (2%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCEH 483 S + + G + GH + I I N ATGS D T ++DL T H Sbjct: 206 SAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTYSH 265 Query: 482 DE---GVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNS 312 D G+T +++ S R + +G D +WD+L D A +GH D V L V+ DG + Sbjct: 266 DNIICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDDRVSCLGVTDDGMA 325 Query: 311 IVSVSTDKSARVFD 270 + + S D ++++ Sbjct: 326 VATGSWDSFLKIWN 339 Score = 61.6 bits (148), Expect = 2e-09 Identities = 35/123 (28%), Positives = 56/123 (45%), Gaps = 1/123 (0%) Frame = -2 Query: 632 QVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLAR-QAIRSTCEHDEGVTCLAW 456 +V L GHT + C N + T S D T +WD+ Q + H V L+ Sbjct: 133 RVSRELAGHTGYLSCCRFLDD-NQIVTSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSL 191 Query: 455 LGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARV 276 +R SG D ++WD G +TF+GH + ++ +GN+ + S D + R+ Sbjct: 192 APDTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRL 251 Query: 275 FDI 267 FD+ Sbjct: 252 FDL 254 Score = 38.1 bits (87), Expect = 0.024 Identities = 39/164 (23%), Positives = 59/164 (35%), Gaps = 46/164 (28%) Frame = -2 Query: 620 SLVGHTNSIECIGISSRYNWVATGSIDRTLIIWD-LARQAIRSTCEHDEGVTCLAWLGSS 444 +L GH I + + + + S D LIIWD + + V A+ S Sbjct: 49 TLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSG 108 Query: 443 RYVASGCID------------GMVRI---------------------------------W 399 YVA G +D G VR+ W Sbjct: 109 NYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVTSSGDTTCALW 168 Query: 398 DSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFDI 267 D +G TF+GH V SL+++ D VS + D SA+++D+ Sbjct: 169 DIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDV 212 Score = 30.8 bits (68), Expect = 3.8 Identities = 22/96 (22%), Positives = 38/96 (39%) Frame = -2 Query: 554 TGSIDRTLIIWDLARQAIRSTCEHDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLA 375 T +ID I R+ +R H + + W SR + S DG + IWDS + + Sbjct: 33 TNNIDPVGRIQMRTRRTLRG---HLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKV 89 Query: 374 RTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFDI 267 V + A + GN + D ++++ Sbjct: 90 HAIPLRSSWVMTCAYAPSGNYVACGGLDNICSIYNL 125
>GBLP_TOBAC (P49026) Guanine nucleotide-binding protein beta subunit-like| protein Length = 326 Score = 63.5 bits (153), Expect = 5e-10 Identities = 38/125 (30%), Positives = 60/125 (48%), Gaps = 7/125 (5%) Frame = -2 Query: 623 GSLVGHTNSIECIGIS-SRYNWVATGSIDRTLIIWDLARQAI------RSTCEHDEGVTC 465 G++ HT+ + I + + + T S D+++I+W + + R H V Sbjct: 10 GTMRAHTDWVTAIATAVDNSDMIVTSSRDKSIIVWSITKDGPQYGVPRRRLTGHGHFVQD 69 Query: 464 LAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKS 285 + + SG DG +R+WD +G AR F GH V S+A S D IVS S DKS Sbjct: 70 VVLSSDGMFALSGSWDGELRLWDLQAGTTARRFVGHTKDVLSVAFSVDNRQIVSASRDKS 129 Query: 284 ARVFD 270 R+++ Sbjct: 130 IRLWN 134 Score = 52.0 bits (123), Expect = 2e-06 Identities = 32/132 (24%), Positives = 62/132 (46%), Gaps = 5/132 (3%) Frame = -2 Query: 644 INSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDL---ARQAIRSTCEHDEG 474 + +G VGHT + + S + + S D+++ +W+ + I+ H + Sbjct: 93 LQAGTTARRFVGHTKDVLSVAFSVDNRQIVSASRDKSIRLWNTLGECKYTIQDGDSHSDW 152 Query: 473 VTCLAWLGSSRY--VASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSV 300 V+C+ + ++ + SG D V+IW+ + L T +GH V + AVS DG+ S Sbjct: 153 VSCVRFSPNNLQPTIVSGSWDRTVKIWNLTNCKLRLTLAGHTGYVNTPAVSPDGSLCASG 212 Query: 299 STDKSARVFDIS 264 D ++D++ Sbjct: 213 GKDGVILLWDLA 224 Score = 45.1 bits (105), Expect = 2e-04 Identities = 40/153 (26%), Positives = 69/153 (45%), Gaps = 18/153 (11%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCEH 483 +V I ++ + ++ +L GHT + +S + A+G D +++WDLA + E Sbjct: 175 TVKIWNLTNCKLRLTLAGHTGYVNTPAVSPDGSLCASGGKDGVILLWDLAEGKKLYSLES 234 Query: 482 DEGVTCLAWLGSSRYVASGCIDGMVRIW--------DSLSGDLAR--------TFSGHRD 351 + L + +RY + ++IW D L DL + T SG Sbjct: 235 GSIIHSLCF-SPNRYWLCAATESSIKIWDLESKSIVDDLKVDLKQESEMSSEGTASGKNK 293 Query: 350 VV--QSLAVSADGNSIVSVSTDKSARVFDISMF 258 V+ SL+ SADG+++ S TD RV+ I + Sbjct: 294 VIYCTSLSWSADGSTLFSGYTDGLIRVWGIDRY 326 Score = 30.4 bits (67), Expect = 4.9 Identities = 21/79 (26%), Positives = 37/79 (46%), Gaps = 6/79 (7%) Frame = -2 Query: 485 HDEGVTCLAW-LGSSRYVASGCIDGMVRIWDSLS-----GDLARTFSGHRDVVQSLAVSA 324 H + VT +A + +S + + D + +W G R +GH VQ + +S+ Sbjct: 15 HTDWVTAIATAVDNSDMIVTSSRDKSIIVWSITKDGPQYGVPRRRLTGHGHFVQDVVLSS 74 Query: 323 DGNSIVSVSTDKSARVFDI 267 DG +S S D R++D+ Sbjct: 75 DGMFALSGSWDGELRLWDL 93
>YCW2_YEAST (P25382) Hypothetical WD-repeat protein YCR072C| Length = 515 Score = 63.2 bits (152), Expect = 7e-10 Identities = 43/131 (32%), Positives = 66/131 (50%), Gaps = 12/131 (9%) Frame = -2 Query: 620 SLVGHTNSIECIGISSRYNWVATGSIDRTLIIWD-----LARQAIRSTCEHDEGVTCLAW 456 +L GH N + C+ S +ATGS+D T+ +WD A+R H + +T L+W Sbjct: 181 TLKGHYNWVLCVSWSPDGEVIATGSMDNTIRLWDPKSGQCLGDALRG---HSKWITSLSW 237 Query: 455 L-------GSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVS 297 GS +AS DG ++IWD++S T SGH + V + G + S S Sbjct: 238 EPIHLVKPGSKPRLASSSKDGTIKIWDTVSRVCQYTMSGHTNSVSCVKWGGQG-LLYSGS 296 Query: 296 TDKSARVFDIS 264 D++ RV+DI+ Sbjct: 297 HDRTVRVWDIN 307 Score = 55.5 bits (132), Expect = 1e-07 Identities = 30/100 (30%), Positives = 49/100 (49%), Gaps = 2/100 (2%) Frame = -2 Query: 560 VATGSIDRTLIIWDLARQA--IRSTCEHDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLS 387 + T S D T+ +W+ + I H + V +A+ RY+ S D +++WD Sbjct: 374 MVTASDDYTMFLWNPLKSTKPIARMTGHQKLVNHVAFSPDGRYIVSASFDNSIKLWDGRD 433 Query: 386 GDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFDI 267 G TF GH V +A S+D +VS S D + +V+D+ Sbjct: 434 GKFISTFRGHVASVYQVAWSSDCRLLVSCSKDTTLKVWDV 473 Score = 53.9 bits (128), Expect = 4e-07 Identities = 31/125 (24%), Positives = 56/125 (44%), Gaps = 1/125 (0%) Frame = -2 Query: 644 INSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCE-HDEGVT 468 + S + + + GH + + S ++ + S D ++ +WD ST H V Sbjct: 389 LKSTKPIARMTGHQKLVNHVAFSPDGRYIVSASFDNSIKLWDGRDGKFISTFRGHVASVY 448 Query: 467 CLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDK 288 +AW R + S D +++WD + L+ GH+D V ++ S DG + S DK Sbjct: 449 QVAWSSDCRLLVSCSKDTTLKVWDVRTRKLSVDLPGHKDEVYTVDWSVDGKRVCSGGKDK 508 Query: 287 SARVF 273 R++ Sbjct: 509 MVRLW 513 Score = 50.8 bits (120), Expect = 4e-06 Identities = 30/99 (30%), Positives = 48/99 (48%), Gaps = 3/99 (3%) Frame = -2 Query: 620 SLVGHTNSIECIGISSRYNW-VATGSIDRTLIIWDLARQAIRSTCE-HDEGVTCLAWLGS 447 ++ GH ++I C + + + TG+ D T IWD Q T + H V C++W Sbjct: 138 AIAGHGSTILCSAFAPHTSSRMVTGAGDNTARIWDCDTQTPMHTLKGHYNWVLCVSWSPD 197 Query: 446 SRYVASGCIDGMVRIWDSLSGD-LARTFSGHRDVVQSLA 333 +A+G +D +R+WD SG L GH + SL+ Sbjct: 198 GEVIATGSMDNTIRLWDPKSGQCLGDALRGHSKWITSLS 236 Score = 41.2 bits (95), Expect = 0.003 Identities = 26/82 (31%), Positives = 38/82 (46%), Gaps = 2/82 (2%) Frame = -2 Query: 560 VATGSIDRTLIIWDLARQAIRSTCE-HDEGVTCLAWLGSSRYVASGCIDGMVRIWD-SLS 387 +A+ S D T+ IWD + + T H V+C+ W G + SG D VR+WD + Sbjct: 251 LASSSKDGTIKIWDTVSRVCQYTMSGHTNSVSCVKW-GGQGLLYSGSHDRTVRVWDINSQ 309 Query: 386 GDLARTFSGHRDVVQSLAVSAD 321 G H V L++S D Sbjct: 310 GRCINILKSHAHWVNHLSLSTD 331 Score = 39.3 bits (90), Expect = 0.011 Identities = 25/89 (28%), Positives = 41/89 (46%), Gaps = 1/89 (1%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDL-ARQAIRSTCE 486 S+ + G+ + + GH S+ + SS + + S D TL +WD+ R+ Sbjct: 425 SIKLWDGRDGKFISTFRGHVASVYQVAWSSDCRLLVSCSKDTTLKVWDVRTRKLSVDLPG 484 Query: 485 HDEGVTCLAWLGSSRYVASGCIDGMVRIW 399 H + V + W + V SG D MVR+W Sbjct: 485 HKDEVYTVDWSVDGKRVCSGGKDKMVRLW 513 Score = 36.2 bits (82), Expect = 0.090 Identities = 25/74 (33%), Positives = 36/74 (48%), Gaps = 2/74 (2%) Frame = -2 Query: 485 HDEGVTCLAWLG--SSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNS 312 H + C A+ SSR V +G D RIWD + T GH + V ++ S DG Sbjct: 142 HGSTILCSAFAPHTSSRMV-TGAGDNTARIWDCDTQTPMHTLKGHYNWVLCVSWSPDGEV 200 Query: 311 IVSVSTDKSARVFD 270 I + S D + R++D Sbjct: 201 IATGSMDNTIRLWD 214
>APAF_RAT (Q9EPV5) Apoptotic protease-activating factor 1 (Apaf-1)| Length = 1249 Score = 62.8 bits (151), Expect = 9e-10 Identities = 34/134 (25%), Positives = 67/134 (50%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCEH 483 ++ I+ + + +V S +GH ++ I ++ + + S D + +W+ + H Sbjct: 984 AIKIIELPNNRVFSSGIGHKKAVRHIQFTADGKTLISSSEDSVIQVWNWQTEEYVFLQAH 1043 Query: 482 DEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVS 303 E V L SR + S DG V++W+ ++G + R F+ H+ V S A+S+D S Sbjct: 1044 QETVKDFRLLRDSRLL-SWSFDGTVKVWNVITGRIERDFTCHQGTVLSCAISSDATKFSS 1102 Query: 302 VSTDKSARVFDISM 261 S DK+A+++ + Sbjct: 1103 TSADKTAKIWSFEL 1116 Score = 62.4 bits (150), Expect = 1e-09 Identities = 36/143 (25%), Positives = 68/143 (47%), Gaps = 3/143 (2%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCE- 486 ++ + +G+ + + H + + C SS +++AT S+D+ + IWD + T E Sbjct: 638 TLQVFKAETGEKLLDIKAHEDEVLCCAFSSDDSYIATCSVDKKVKIWDSGTGKLVHTYEE 697 Query: 485 HDEGVTCLAWLGSSRYV--ASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNS 312 H E V C + S ++ A+G D +++WD + T GH + V S D Sbjct: 698 HSEQVNCCHFTNKSNHLLLATGSNDSFLKLWDLNQKECRNTMFGHTNSVTHCRFSPDDEL 757 Query: 311 IVSVSTDKSARVFDISMFK*EKS 243 + S S D + +++D+ +KS Sbjct: 758 LASCSADGTLKLWDVRSANEKKS 780 Score = 45.8 bits (107), Expect = 1e-04 Identities = 28/118 (23%), Positives = 57/118 (48%), Gaps = 3/118 (2%) Frame = -2 Query: 608 HTNSIECIGISSRYNWVATGSIDRTLIIWDLAR-QAIRSTCEHDEGVTCLAWLGSSRYVA 432 HT+++ S +A+ D+TL ++ + + H++ V C A+ Y+A Sbjct: 614 HTDAVYHACFSQDGQRIASCGADKTLQVFKAETGEKLLDIKAHEDEVLCCAFSSDDSYIA 673 Query: 431 SGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIV--SVSTDKSARVFDIS 264 + +D V+IWDS +G L T+ H + V + N ++ + S D +++D++ Sbjct: 674 TCSVDKKVKIWDSGTGKLVHTYEEHSEQVNCCHFTNKSNHLLLATGSNDSFLKLWDLN 731 Score = 35.0 bits (79), Expect = 0.20 Identities = 23/96 (23%), Positives = 44/96 (45%), Gaps = 1/96 (1%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQA-IRSTCE 486 +V + ++ +G++ H ++ ISS ++ S D+T IW + + Sbjct: 1066 TVKVWNVITGRIERDFTCHQGTVLSCAISSDATKFSSTSADKTAKIWSFELPSPLHELKG 1125 Query: 485 HDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDL 378 H+ V C A+ +A+G +G +RIW+ G L Sbjct: 1126 HNSCVRCSAFSLDGILLATGDDNGEIRIWNVSDGQL 1161 Score = 34.3 bits (77), Expect = 0.34 Identities = 18/68 (26%), Positives = 36/68 (52%) Frame = -2 Query: 473 VTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVST 294 V+C YVA G +G ++I + + + + GH+ V+ + +ADG +++S S Sbjct: 964 VSCCCLSPHLEYVAFGDEEGAIKIIELPNNRVFSSGIGHKKAVRHIQFTADGKTLISSSE 1023 Query: 293 DKSARVFD 270 D +V++ Sbjct: 1024 DSVIQVWN 1031 Score = 32.3 bits (72), Expect = 1.3 Identities = 25/116 (21%), Positives = 52/116 (44%), Gaps = 10/116 (8%) Frame = -2 Query: 617 LVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAI----------RSTCEHDEGVT 468 L GH + + C S +ATG + + IW+++ + T H VT Sbjct: 1123 LKGHNSCVRCSAFSLDGILLATGDDNGEIRIWNVSDGQLLHLCAPISIEEGTATHGGWVT 1182 Query: 467 CLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSV 300 + + + + S G ++ W+ ++G+ ++TF + ++ + VS D + V+V Sbjct: 1183 DVCFSPDRKMLVSA--GGYLKWWNVVTGESSQTFYTNGTNLKKIHVSPDFRTYVTV 1236 Score = 30.8 bits (68), Expect = 3.8 Identities = 21/97 (21%), Positives = 41/97 (42%), Gaps = 2/97 (2%) Frame = -2 Query: 548 SIDRTLIIWDLARQAIRS--TCEHDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLA 375 S D T+ +W++ I TC ++C ++++ +S D +IW Sbjct: 1062 SFDGTVKVWNVITGRIERDFTCHQGTVLSCAISSDATKF-SSTSADKTAKIWSFELPSPL 1120 Query: 374 RTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFDIS 264 GH V+ A S DG + + + R++++S Sbjct: 1121 HELKGHNSCVRCSAFSLDGILLATGDDNGEIRIWNVS 1157
>PWP2_SCHPO (Q9C1X1) Periodic tryptophan protein 2 homolog| Length = 854 Score = 62.4 bits (150), Expect = 1e-09 Identities = 39/134 (29%), Positives = 68/134 (50%), Gaps = 3/134 (2%) Frame = -2 Query: 659 VHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCEHD 480 + + +NSG + + HT+++ + S R N + + S+D ++ WDL R T Sbjct: 363 IKVWDMNSGFCIVTFTQHTSAVSGLCFSKRGNVLFSSSLDGSVRAWDLIRYRNFRTFTAP 422 Query: 479 EGV--TCLAWLGSSRYVASGCIDGM-VRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSI 309 V +C+A S V +G D + +W +G L T +GH V SL+ ++ G+ + Sbjct: 423 SRVQFSCIAVDPSGEIVCAGSQDSFEIFMWSVQTGQLLETLAGHEGPVSSLSFNSSGSLL 482 Query: 308 VSVSTDKSARVFDI 267 S S DK+ R++DI Sbjct: 483 ASGSWDKTVRIWDI 496 Score = 59.3 bits (142), Expect = 1e-08 Identities = 31/118 (26%), Positives = 61/118 (51%), Gaps = 2/118 (1%) Frame = -2 Query: 602 NSIECIGISSRYNWVATGSIDR-TLIIWDLARQA-IRSTCEHDEGVTCLAWLGSSRYVAS 429 ++I+ + ++S +W+A GS L++W+ ++ + H + ++ L + + + + Sbjct: 297 SNIDTLTVNSTGDWIAIGSSKLGQLLVWEWQSESYVLKQQSHYDALSTLQYSSDGQRIIT 356 Query: 428 GCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFDISMFK 255 G DG +++WD SG TF+ H V L S GN + S S D S R +D+ ++ Sbjct: 357 GADDGKIKVWDMNSGFCIVTFTQHTSAVSGLCFSKRGNVLFSSSLDGSVRAWDLIRYR 414 Score = 57.8 bits (138), Expect = 3e-08 Identities = 37/148 (25%), Positives = 65/148 (43%), Gaps = 21/148 (14%) Frame = -2 Query: 647 SINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDL-ARQAIRSTCEHDEGV 471 S+ +GQ++ +L GH + + +S + +A+GS D+T+ IWD+ +R I V Sbjct: 453 SVQTGQLLETLAGHEGPVSSLSFNSSGSLLASGSWDKTVRIWDIFSRSGIVEPLPIPSDV 512 Query: 470 TCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDV------------------- 348 LA+ + V +DG + W+ G G +D+ Sbjct: 513 LSLAFHPDGKEVCVASLDGQLTFWNVQEGKQTSLIDGRKDLSGGRRFDDARTAENSSLNK 572 Query: 347 -VQSLAVSADGNSIVSVSTDKSARVFDI 267 S+ SADG+ ++S T K ++DI Sbjct: 573 TFTSICYSADGSCVLSAGTSKYVCLYDI 600 Score = 30.8 bits (68), Expect = 3.8 Identities = 14/38 (36%), Positives = 23/38 (60%) Frame = -2 Query: 380 LARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFDI 267 L R ++GH D + S++ SAD +S S D +AR+ + Sbjct: 138 LHREYTGHFDDIVSISWSADSRFFISTSKDLTARLHSV 175
>GBB4_HUMAN (Q9HAV0) Guanine nucleotide-binding protein beta subunit 4| (Transducin beta chain 4) Length = 339 Score = 62.4 bits (150), Expect = 1e-09 Identities = 39/128 (30%), Positives = 59/128 (46%), Gaps = 3/128 (2%) Frame = -2 Query: 644 INSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCEHDE---G 474 I G S GH + I + ATGS D T ++DL HD G Sbjct: 212 IRDGMCRQSFTGHVSDINAVSFFPNGYAFATGSDDATCRLFDLRADQELLLYSHDNIICG 271 Query: 473 VTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVST 294 +T +A+ S R + +G D +WD+L GD A +GH + V L V+ DG ++ + S Sbjct: 272 ITSVAFSKSGRLLLAGYDDFNCNVWDTLKGDRAGVLAGHDNRVSCLGVTDDGMAVATGSW 331 Query: 293 DKSARVFD 270 D R+++ Sbjct: 332 DSFLRIWN 339 Score = 51.6 bits (122), Expect = 2e-06 Identities = 32/123 (26%), Positives = 55/123 (44%), Gaps = 1/123 (0%) Frame = -2 Query: 632 QVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDL-ARQAIRSTCEHDEGVTCLAW 456 +V L GHT + C + + T S D T +WD+ Q + H V L+ Sbjct: 133 RVSRELPGHTGYLSCCRFLDD-SQIVTSSGDTTCALWDIETAQQTTTFTGHSGDVMSLSL 191 Query: 455 LGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARV 276 R SG D ++WD G ++F+GH + +++ +G + + S D + R+ Sbjct: 192 SPDMRTFVSGACDASSKLWDIRDGMCRQSFTGHVSDINAVSFFPNGYAFATGSDDATCRL 251 Query: 275 FDI 267 FD+ Sbjct: 252 FDL 254
>GBB1_CRIGR (Q6TMK6) Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta| subunit 1 (Transducin beta chain 1) Length = 339 Score = 62.4 bits (150), Expect = 1e-09 Identities = 35/123 (28%), Positives = 57/123 (46%), Gaps = 1/123 (0%) Frame = -2 Query: 632 QVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLAR-QAIRSTCEHDEGVTCLAW 456 +V L GHT + C + N + T S D T +WD+ Q + H V L+ Sbjct: 133 RVSRELAGHTGYLSCCRFLND-NQIVTSSEDTTCALWDIETGQQTTTFTGHTGDVMSLSL 191 Query: 455 LGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARV 276 +R SG D ++WD G +TF+GH + ++ +GN+ + S D + R+ Sbjct: 192 APDTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRL 251 Query: 275 FDI 267 FD+ Sbjct: 252 FDL 254 Score = 61.6 bits (148), Expect = 2e-09 Identities = 38/134 (28%), Positives = 62/134 (46%), Gaps = 3/134 (2%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCEH 483 S + + G + GH + I I N ATGS D T ++DL T H Sbjct: 206 SAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTYSH 265 Query: 482 DE---GVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNS 312 D G+T +++ S R + +G D +WD+L D A +GH + V L V+ DG + Sbjct: 266 DNIICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDNRVSCLGVTDDGMA 325 Query: 311 IVSVSTDKSARVFD 270 + + S D ++++ Sbjct: 326 VATGSWDSFLKIWN 339 Score = 38.1 bits (87), Expect = 0.024 Identities = 39/164 (23%), Positives = 59/164 (35%), Gaps = 46/164 (28%) Frame = -2 Query: 620 SLVGHTNSIECIGISSRYNWVATGSIDRTLIIWD-LARQAIRSTCEHDEGVTCLAWLGSS 444 +L GH I + + + + S D LIIWD + + V A+ S Sbjct: 49 TLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSG 108 Query: 443 RYVASGCID------------GMVRI---------------------------------W 399 YVA G +D G VR+ W Sbjct: 109 NYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLNDNQIVTSSEDTTCALW 168 Query: 398 DSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFDI 267 D +G TF+GH V SL+++ D VS + D SA+++D+ Sbjct: 169 DIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDV 212 Score = 30.0 bits (66), Expect = 6.5 Identities = 22/96 (22%), Positives = 38/96 (39%) Frame = -2 Query: 554 TGSIDRTLIIWDLARQAIRSTCEHDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLA 375 T +ID I R+ +R H + + W SR + S DG + IWDS + + Sbjct: 33 TTNIDPVGRIQMRTRRTLRG---HLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKV 89 Query: 374 RTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFDI 267 V + A + GN + D ++++ Sbjct: 90 HAIPLRSSWVMTCAYAPSGNYVACGGLDNICSIYNL 125
>PLRG1_RAT (Q9WUC8) Pleiotropic regulator 1| Length = 514 Score = 62.0 bits (149), Expect = 2e-09 Identities = 37/116 (31%), Positives = 55/116 (47%), Gaps = 1/116 (0%) Frame = -2 Query: 611 GHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIR-STCEHDEGVTCLAWLGSSRYV 435 GH + CI + W TGS DRT+ IWDLA ++ S H V + S Y+ Sbjct: 202 GHLGWVRCIAVEPGNQWFVTGSADRTIKIWDLASGKLKLSLTGHISTVRGVIVSTRSPYL 261 Query: 434 ASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFDI 267 S D V+ WD + R + GH V L + + +V+ S D +AR++D+ Sbjct: 262 FSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYGLDLHPTIDVLVTCSRDSTARIWDV 317 Score = 52.4 bits (124), Expect = 1e-06 Identities = 33/116 (28%), Positives = 53/116 (45%), Gaps = 1/116 (0%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRST-CE 486 + I + + V +L GHTN++ + + + TGS D T+ +WDL R T Sbjct: 311 TARIWDVRTKASVHTLSGHTNAVATVRCQAAEPQIITGSHDTTIRLWDLVAGKTRVTLTN 370 Query: 485 HDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADG 318 H + V + ASG D ++ W G + SGH ++ +LAV+ DG Sbjct: 371 HKKSVRAVVLHPLHYTFASGSPDN-IKQWKFPDGGFIQNLSGHNAIINTLAVNTDG 425 Score = 43.1 bits (100), Expect = 7e-04 Identities = 24/90 (26%), Positives = 40/90 (44%) Frame = -2 Query: 524 WDLARQAIRSTCEHDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVV 345 W + R H V C+A +++ +G D ++IWD SG L + +GH V Sbjct: 190 WHPPWKLYRVISGHLGWVRCIAVEPGNQWFVTGSADRTIKIWDLASGKLKLSLTGHISTV 249 Query: 344 QSLAVSADGNSIVSVSTDKSARVFDISMFK 255 + + VS + S DK + +D+ K Sbjct: 250 RGVIVSTRSPYLFSCGEDKQVKCWDLEYNK 279
>PLRG1_HUMAN (O43660) Pleiotropic regulator 1| Length = 514 Score = 62.0 bits (149), Expect = 2e-09 Identities = 37/116 (31%), Positives = 55/116 (47%), Gaps = 1/116 (0%) Frame = -2 Query: 611 GHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIR-STCEHDEGVTCLAWLGSSRYV 435 GH + CI + W TGS DRT+ IWDLA ++ S H V + S Y+ Sbjct: 202 GHLGWVRCIAVEPGNQWFVTGSADRTIKIWDLASGKLKLSLTGHISTVRGVIVSTRSPYL 261 Query: 434 ASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFDI 267 S D V+ WD + R + GH V L + + +V+ S D +AR++D+ Sbjct: 262 FSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYGLDLHPTIDVLVTCSRDSTARIWDV 317 Score = 52.0 bits (123), Expect = 2e-06 Identities = 32/116 (27%), Positives = 53/116 (45%), Gaps = 1/116 (0%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRST-CE 486 + I + + V +L GHTN++ + + + TGS D T+ +WDL R T Sbjct: 311 TARIWDVRTKASVHTLSGHTNAVATVRCQAAEPQIITGSHDTTIRLWDLVAGKTRVTLTN 370 Query: 485 HDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADG 318 H + V + ASG D ++ W G + SGH ++ +L V++DG Sbjct: 371 HKKSVRAVVLHPRHYTFASGSPDN-IKQWKFPDGSFIQNLSGHNAIINTLTVNSDG 425 Score = 43.1 bits (100), Expect = 7e-04 Identities = 24/90 (26%), Positives = 40/90 (44%) Frame = -2 Query: 524 WDLARQAIRSTCEHDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVV 345 W + R H V C+A +++ +G D ++IWD SG L + +GH V Sbjct: 190 WHPPWKLYRVISGHLGWVRCIAVEPGNQWFVTGSADRTIKIWDLASGKLKLSLTGHISTV 249 Query: 344 QSLAVSADGNSIVSVSTDKSARVFDISMFK 255 + + VS + S DK + +D+ K Sbjct: 250 RGVIVSTRSPYLFSCGEDKQVKCWDLEYNK 279
>GBLP_SOYBN (Q39836) Guanine nucleotide-binding protein beta subunit-like| protein Length = 325 Score = 62.0 bits (149), Expect = 2e-09 Identities = 37/125 (29%), Positives = 61/125 (48%), Gaps = 7/125 (5%) Frame = -2 Query: 623 GSLVGHTNSIECIGIS-SRYNWVATGSIDRTLIIWDLARQ------AIRSTCEHDEGVTC 465 G++ HT+ + I + + T S DR++I+W L ++ R H V Sbjct: 9 GTMRAHTDVVTAIATPIDNSDMIVTASRDRSIILWHLTKEDKTYGVPRRRLTGHSHFVQD 68 Query: 464 LAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKS 285 + ++ SG DG +R+WD +G AR F GH V S+A S D IVS S D++ Sbjct: 69 VVLSSDGQFALSGSWDGELRLWDLAAGTSARRFVGHTKDVLSVAFSIDNRQIVSASRDRT 128 Query: 284 ARVFD 270 ++++ Sbjct: 129 IKLWN 133 Score = 53.9 bits (128), Expect = 4e-07 Identities = 33/130 (25%), Positives = 61/130 (46%), Gaps = 5/130 (3%) Frame = -2 Query: 638 SGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDL---ARQAIRSTCEHDEGVT 468 +G VGHT + + S + + S DRT+ +W+ + I+ H + V+ Sbjct: 94 AGTSARRFVGHTKDVLSVAFSIDNRQIVSASRDRTIKLWNTLGECKYTIQDGDAHSDWVS 153 Query: 467 CLAWLGSSRY--VASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVST 294 C+ + S+ + S D V++W+ + L T +GH V ++AVS DG+ S Sbjct: 154 CVRFSPSTLQPTIVSASWDRTVKVWNLTNCKLRNTLAGHNGYVNTVAVSPDGSLCASGGK 213 Query: 293 DKSARVFDIS 264 D ++D++ Sbjct: 214 DGVILLWDLA 223 Score = 43.5 bits (101), Expect = 6e-04 Identities = 36/153 (23%), Positives = 65/153 (42%), Gaps = 18/153 (11%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCEH 483 +V + ++ + ++ +L GH + + +S + A+G D +++WDLA + + Sbjct: 174 TVKVWNLTNCKLRNTLAGHNGYVNTVAVSPDGSLCASGGKDGVILLWDLAEGKRLYSLDA 233 Query: 482 DEGVTCLAWLGSSRYVASGCIDGMVRIWD----SLSGDLARTFSGHRDVVQ--------- 342 + L + SRY + ++IWD S+ DL D Sbjct: 234 GSIIHALCF-SPSRYWLCAATEQSIKIWDLESKSIVEDLKVDLKTEADATSGGGNANKKK 292 Query: 341 -----SLAVSADGNSIVSVSTDKSARVFDISMF 258 SL SADG+++ S TD ARV+ I + Sbjct: 293 VIYCTSLNWSADGSTLFSGYTDGVARVWAIGRY 325 Score = 33.9 bits (76), Expect = 0.45 Identities = 22/80 (27%), Positives = 39/80 (48%), Gaps = 6/80 (7%) Frame = -2 Query: 485 HDEGVTCLAW-LGSSRYVASGCIDGMVRIW-----DSLSGDLARTFSGHRDVVQSLAVSA 324 H + VT +A + +S + + D + +W D G R +GH VQ + +S+ Sbjct: 14 HTDVVTAIATPIDNSDMIVTASRDRSIILWHLTKEDKTYGVPRRRLTGHSHFVQDVVLSS 73 Query: 323 DGNSIVSVSTDKSARVFDIS 264 DG +S S D R++D++ Sbjct: 74 DGQFALSGSWDGELRLWDLA 93
>GBLP_CAEEL (Q21215) Guanine nucleotide-binding protein beta subunit 2-like 1| Length = 324 Score = 62.0 bits (149), Expect = 2e-09 Identities = 41/133 (30%), Positives = 66/133 (49%), Gaps = 12/133 (9%) Frame = -2 Query: 632 QVVGSLVGHTNSIECIGISSRYN--WVATGSIDRTLIIWDLARQA----------IRSTC 489 ++ G+L GHT + I +R + V + S D+T+++WD+ A +RS Sbjct: 6 KLTGTLEGHTGWVTQIATYTRNDKTTVLSSSRDKTILVWDVDSVAPVDEGPIGRPVRSLT 65 Query: 488 EHDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSI 309 H+ V+ + ++ SG D +R+WD G R F H V S+A SAD I Sbjct: 66 GHNHFVSDVVISSDGQFALSGSWDKTLRLWDLNQGVSTRQFISHTKDVLSVAFSADNRQI 125 Query: 308 VSVSTDKSARVFD 270 VS S DKS ++++ Sbjct: 126 VSGSRDKSIKLWN 138 Score = 56.6 bits (135), Expect = 6e-08 Identities = 38/127 (29%), Positives = 65/127 (51%), Gaps = 4/127 (3%) Frame = -2 Query: 635 GQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLAR-QAIRSTCEHDEGVTCLA 459 G+ V SL GH + + + ISS + +GS D+TL +WDL + + R H + V +A Sbjct: 58 GRPVRSLTGHNHFVSDVVISSDGQFALSGSWDKTLRLWDLNQGVSTRQFISHTKDVLSVA 117 Query: 458 WLGSSRYVASGCIDGMVRIWDSLSG-DLARTFSGHRDVVQSLAVSADGNS--IVSVSTDK 288 + +R + SG D +++W++L+ T H D V ++ S IVS DK Sbjct: 118 FSADNRQIVSGSRDKSIKLWNTLAQCKYTITDDCHTDWVSTVRFSPSNRDPVIVSAGWDK 177 Query: 287 SARVFDI 267 +V+++ Sbjct: 178 VVKVWNL 184 Score = 50.1 bits (118), Expect = 6e-06 Identities = 32/138 (23%), Positives = 65/138 (47%), Gaps = 5/138 (3%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQA---IRST 492 ++ + +N G + HT + + S+ + +GS D+++ +W+ Q I Sbjct: 91 TLRLWDLNQGVSTRQFISHTKDVLSVAFSADNRQIVSGSRDKSIKLWNTLAQCKYTITDD 150 Query: 491 CEHDEGVTCLAWLGSSR--YVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADG 318 C H + V+ + + S+R + S D +V++W+ + L GH V ++ VS DG Sbjct: 151 C-HTDWVSTVRFSPSNRDPVIVSAGWDKVVKVWNLGNCRLKTNHIGHTGYVNTVTVSPDG 209 Query: 317 NSIVSVSTDKSARVFDIS 264 + S D A ++D++ Sbjct: 210 SLCASGGKDGQAMLWDLN 227 Score = 43.9 bits (102), Expect = 4e-04 Identities = 31/128 (24%), Positives = 58/128 (45%), Gaps = 10/128 (7%) Frame = -2 Query: 614 VGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCEHDEGVTCLAWLGSSRYV 435 +GHT + + +S + A+G D ++WDL T ++ + +++ +RY Sbjct: 194 IGHTGYVNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLPGNDVINAMSF-SPNRYW 252 Query: 434 ASGCIDGMVRIWD--------SLSGDLARTFSGHRDVVQ--SLAVSADGNSIVSVSTDKS 285 + ++IWD L ++A + S Q SLA S DG ++ + TD Sbjct: 253 LCAAVGSSIKIWDLEDKKEIEELKPEIASSGSSRGSSPQCISLAWSQDGQTLFAGYTDNI 312 Query: 284 ARVFDISM 261 RV+ +S+ Sbjct: 313 IRVYQVSI 320
>GBB1_XENLA (P79959) Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta| subunit 1 (Transducin beta chain 1) (XGbeta1) Length = 340 Score = 62.0 bits (149), Expect = 2e-09 Identities = 36/123 (29%), Positives = 56/123 (45%), Gaps = 1/123 (0%) Frame = -2 Query: 632 QVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLAR-QAIRSTCEHDEGVTCLAW 456 +V L GHT + C N + T S D T +WD+ Q + H V L+ Sbjct: 134 RVSRELAGHTGYLSCCRFLDD-NQIITSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSL 192 Query: 455 LGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARV 276 SR SG D ++WD G +TF+GH + ++ +GN+ + S D + R+ Sbjct: 193 APDSRCFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRL 252 Query: 275 FDI 267 FD+ Sbjct: 253 FDL 255 Score = 60.8 bits (146), Expect = 3e-09 Identities = 38/134 (28%), Positives = 61/134 (45%), Gaps = 3/134 (2%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCEH 483 S + + G + GH + I I N ATGS D T ++DL H Sbjct: 207 SAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQELMVYSH 266 Query: 482 DE---GVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNS 312 D G+T +A+ S R + +G D +WD+L D A +GH + V L V+ DG + Sbjct: 267 DNIICGITSVAFSKSGRLLLAGYDDFNCNVWDTLKADRAGVLAGHDNRVSCLGVTDDGMA 326 Query: 311 IVSVSTDKSARVFD 270 + + S D ++++ Sbjct: 327 VATGSWDSFLKIWN 340 Score = 39.3 bits (90), Expect = 0.011 Identities = 39/164 (23%), Positives = 59/164 (35%), Gaps = 46/164 (28%) Frame = -2 Query: 620 SLVGHTNSIECIGISSRYNWVATGSIDRTLIIWD-LARQAIRSTCEHDEGVTCLAWLGSS 444 +L GH I + + + + S D LIIWD + + V A+ S Sbjct: 50 TLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSG 109 Query: 443 RYVASGCID------------GMVRI---------------------------------W 399 YVA G +D G VR+ W Sbjct: 110 NYVACGGLDNICPIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIITSSGDTTCALW 169 Query: 398 DSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFDI 267 D +G TF+GH V SL+++ D VS + D SA+++D+ Sbjct: 170 DIETGQQTTTFTGHTGDVMSLSLAPDSRCFVSGACDASAKLWDV 213 Score = 30.4 bits (67), Expect = 4.9 Identities = 22/96 (22%), Positives = 38/96 (39%) Frame = -2 Query: 554 TGSIDRTLIIWDLARQAIRSTCEHDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLA 375 T +ID I R+ +R H + + W SR + S DG + IWDS + + Sbjct: 34 TANIDPVGRIQMRTRRTLRG---HLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKV 90 Query: 374 RTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFDI 267 V + A + GN + D ++++ Sbjct: 91 HAIPLRSSWVMTCAYAPSGNYVACGGLDNICPIYNL 126
>GBB1_BRARE (Q6PH57) Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta| subunit 1 (Transducin beta chain 1) Length = 340 Score = 62.0 bits (149), Expect = 2e-09 Identities = 35/123 (28%), Positives = 56/123 (45%), Gaps = 1/123 (0%) Frame = -2 Query: 632 QVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLAR-QAIRSTCEHDEGVTCLAW 456 +V L GHT + C N + T S D T +WD+ Q + H V L+ Sbjct: 134 RVSRELAGHTGYLSCCRFLDD-NQIVTSSGDTTCALWDIETGQQTTTFAGHTGDVMSLSL 192 Query: 455 LGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARV 276 +R SG D ++WD G +TF+GH + ++ +GN+ + S D + R+ Sbjct: 193 APDTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRL 252 Query: 275 FDI 267 FD+ Sbjct: 253 FDL 255 Score = 60.8 bits (146), Expect = 3e-09 Identities = 38/134 (28%), Positives = 61/134 (45%), Gaps = 3/134 (2%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCEH 483 S + + G + GH + I I N ATGS D T ++DL H Sbjct: 207 SAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQELMVYSH 266 Query: 482 DE---GVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNS 312 D G+T +A+ S R + +G D +WD+L D A +GH + V L V+ DG + Sbjct: 267 DNIICGITSVAFSKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDNRVSCLGVTDDGMA 326 Query: 311 IVSVSTDKSARVFD 270 + + S D ++++ Sbjct: 327 VATGSWDSFLKIWN 340 Score = 38.1 bits (87), Expect = 0.024 Identities = 39/164 (23%), Positives = 59/164 (35%), Gaps = 46/164 (28%) Frame = -2 Query: 620 SLVGHTNSIECIGISSRYNWVATGSIDRTLIIWD-LARQAIRSTCEHDEGVTCLAWLGSS 444 +L GH I + + + + S D LIIWD + + V A+ S Sbjct: 50 TLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSG 109 Query: 443 RYVASGCID------------GMVRI---------------------------------W 399 YVA G +D G VR+ W Sbjct: 110 NYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVTSSGDTTCALW 169 Query: 398 DSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFDI 267 D +G TF+GH V SL+++ D VS + D SA+++D+ Sbjct: 170 DIETGQQTTTFAGHTGDVMSLSLAPDTRLFVSGACDASAKLWDV 213 Score = 30.8 bits (68), Expect = 3.8 Identities = 22/96 (22%), Positives = 38/96 (39%) Frame = -2 Query: 554 TGSIDRTLIIWDLARQAIRSTCEHDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLA 375 T +ID I R+ +R H + + W SR + S DG + IWDS + + Sbjct: 34 TANIDPVGRIQMRTRRTLRG---HLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKV 90 Query: 374 RTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFDI 267 V + A + GN + D ++++ Sbjct: 91 HAIPLRSSWVMTCAYAPSGNYVACGGLDNICSIYNL 126
>PLRG1_MOUSE (Q922V4) Pleiotropic regulator 1| Length = 513 Score = 62.0 bits (149), Expect = 2e-09 Identities = 37/116 (31%), Positives = 55/116 (47%), Gaps = 1/116 (0%) Frame = -2 Query: 611 GHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIR-STCEHDEGVTCLAWLGSSRYV 435 GH + CI + W TGS DRT+ IWDLA ++ S H V + S Y+ Sbjct: 201 GHLGWVRCIAVEPGNQWFVTGSADRTIKIWDLASGKLKLSLTGHISTVRGVIVSTRSPYL 260 Query: 434 ASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFDI 267 S D V+ WD + R + GH V L + + +V+ S D +AR++D+ Sbjct: 261 FSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYGLDLHPTLDVLVTCSRDSTARIWDV 316 Score = 53.5 bits (127), Expect = 5e-07 Identities = 34/116 (29%), Positives = 54/116 (46%), Gaps = 1/116 (0%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRST-CE 486 + I + + V +L GHTN++ + + + TGS D T+ +WDL R T Sbjct: 310 TARIWDVRTKASVHTLSGHTNAVATVRCQAAEPQIITGSHDTTIRLWDLVAGKTRVTLTN 369 Query: 485 HDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADG 318 H + V + ASG D ++ W G + SGH ++ +LAV+ADG Sbjct: 370 HKKSVRAVVLHPLLYTFASGSPDN-IKQWKFPDGGFIQNLSGHNAIINTLAVNADG 424 Score = 43.1 bits (100), Expect = 7e-04 Identities = 24/90 (26%), Positives = 40/90 (44%) Frame = -2 Query: 524 WDLARQAIRSTCEHDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVV 345 W + R H V C+A +++ +G D ++IWD SG L + +GH V Sbjct: 189 WHPPWKLYRVISGHLGWVRCIAVEPGNQWFVTGSADRTIKIWDLASGKLKLSLTGHISTV 248 Query: 344 QSLAVSADGNSIVSVSTDKSARVFDISMFK 255 + + VS + S DK + +D+ K Sbjct: 249 RGVIVSTRSPYLFSCGEDKQVKCWDLEYNK 278
>COPB2_MOUSE (O55029) Coatomer subunit beta' (Beta'-coat protein) (Beta'-COP)| (p102) Length = 905 Score = 62.0 bits (149), Expect = 2e-09 Identities = 38/127 (29%), Positives = 66/127 (51%), Gaps = 4/127 (3%) Frame = -2 Query: 611 GHTNSIECIGISSR-YNWVATGSIDRTLIIWDLARQAIRSTCE-HDEGVTCLAWL--GSS 444 GHT+ + I I+ + N A+ S+DRT+ +W L + T E H++GV C+ + G Sbjct: 140 GHTHYVMQIVINPKDNNQFASASLDRTIKVWQLGSSSPNFTLEGHEKGVNCIDYYSGGDK 199 Query: 443 RYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFDIS 264 Y+ SG D +V+IWD + +T GH V + + I++ S D + R++ S Sbjct: 200 PYLISGADDRLVKIWDYQNKTCVQTLEGHAQNVSCASFHPELPIIITGSEDGTVRIWHSS 259 Query: 263 MFK*EKS 243 ++ E + Sbjct: 260 TYRLEST 266 Score = 45.8 bits (107), Expect = 1e-04 Identities = 34/130 (26%), Positives = 63/130 (48%), Gaps = 3/130 (2%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYN--WVATGSIDRTLIIWDLARQAIRSTC 489 ++ + + S +L GH + CI S + ++ +G+ DR + IWD + T Sbjct: 166 TIKVWQLGSSSPNFTLEGHEKGVNCIDYYSGGDKPYLISGADDRLVKIWDYQNKTCVQTL 225 Query: 488 E-HDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNS 312 E H + V+C ++ + +G DG VRIW S + L T + + V +A S G++ Sbjct: 226 EGHAQNVSCASFHPELPIIITGSEDGTVRIWHSSTYRLESTLNYGMERVWCVA-SLRGSN 284 Query: 311 IVSVSTDKSA 282 V++ D+ + Sbjct: 285 NVALGYDEGS 294 Score = 44.7 bits (104), Expect = 3e-04 Identities = 23/106 (21%), Positives = 52/106 (49%), Gaps = 3/106 (2%) Frame = -2 Query: 575 SRYNWVATGSIDRTLIIWDL-ARQAIRSTCEHDEGVTCLAWLGSSRYVASGCIDGMVRIW 399 +R NWV TG+ D + +++ + + H + + C+A + ++ + D ++++W Sbjct: 67 ARKNWVVTGADDMQIRVFNYNTLERVHMFEAHSDYIRCIAVHPTQPFILTSSDDMLIKLW 126 Query: 398 D-SLSGDLARTFSGHRDVVQSLAVS-ADGNSIVSVSTDKSARVFDI 267 D ++ F GH V + ++ D N S S D++ +V+ + Sbjct: 127 DWDKKWSCSQVFEGHTHYVMQIVINPKDNNQFASASLDRTIKVWQL 172 Score = 39.3 bits (90), Expect = 0.011 Identities = 24/74 (32%), Positives = 35/74 (47%), Gaps = 1/74 (1%) Frame = -2 Query: 626 VGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCEHD-EGVTCLAWLG 450 V +L GH ++ C + TGS D T+ IW + + ST + E V C+A L Sbjct: 222 VQTLEGHAQNVSCASFHPELPIIITGSEDGTVRIWHSSTYRLESTLNYGMERVWCVASLR 281 Query: 449 SSRYVASGCIDGMV 408 S VA G +G + Sbjct: 282 GSNNVALGYDEGSI 295
>COPB2_HUMAN (P35606) Coatomer subunit beta' (Beta'-coat protein) (Beta'-COP)| (p102) Length = 905 Score = 62.0 bits (149), Expect = 2e-09 Identities = 38/127 (29%), Positives = 66/127 (51%), Gaps = 4/127 (3%) Frame = -2 Query: 611 GHTNSIECIGISSR-YNWVATGSIDRTLIIWDLARQAIRSTCE-HDEGVTCLAWL--GSS 444 GHT+ + I I+ + N A+ S+DRT+ +W L + T E H++GV C+ + G Sbjct: 139 GHTHYVMQIVINPKDNNQFASASLDRTIKVWQLGSSSPNFTLEGHEKGVNCIDYYSGGDK 198 Query: 443 RYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFDIS 264 Y+ SG D +V+IWD + +T GH V + + I++ S D + R++ S Sbjct: 199 PYLISGADDRLVKIWDYQNKTCVQTLEGHAQNVSCASFHPELPIIITGSEDGTVRIWHSS 258 Query: 263 MFK*EKS 243 ++ E + Sbjct: 259 TYRLEST 265 Score = 45.8 bits (107), Expect = 1e-04 Identities = 34/130 (26%), Positives = 63/130 (48%), Gaps = 3/130 (2%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYN--WVATGSIDRTLIIWDLARQAIRSTC 489 ++ + + S +L GH + CI S + ++ +G+ DR + IWD + T Sbjct: 165 TIKVWQLGSSSPNFTLEGHEKGVNCIDYYSGGDKPYLISGADDRLVKIWDYQNKTCVQTL 224 Query: 488 E-HDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNS 312 E H + V+C ++ + +G DG VRIW S + L T + + V +A S G++ Sbjct: 225 EGHAQNVSCASFHPELPIIITGSEDGTVRIWHSSTYRLESTLNYGMERVWCVA-SLRGSN 283 Query: 311 IVSVSTDKSA 282 V++ D+ + Sbjct: 284 NVALGYDEGS 293 Score = 44.7 bits (104), Expect = 3e-04 Identities = 23/106 (21%), Positives = 52/106 (49%), Gaps = 3/106 (2%) Frame = -2 Query: 575 SRYNWVATGSIDRTLIIWDL-ARQAIRSTCEHDEGVTCLAWLGSSRYVASGCIDGMVRIW 399 +R NWV TG+ D + +++ + + H + + C+A + ++ + D ++++W Sbjct: 66 ARKNWVVTGADDMQIRVFNYNTLERVHMFEAHSDYIRCIAVHPTQPFILTSSDDMLIKLW 125 Query: 398 D-SLSGDLARTFSGHRDVVQSLAVS-ADGNSIVSVSTDKSARVFDI 267 D ++ F GH V + ++ D N S S D++ +V+ + Sbjct: 126 DWDKKWSCSQVFEGHTHYVMQIVINPKDNNQFASASLDRTIKVWQL 171 Score = 39.3 bits (90), Expect = 0.011 Identities = 24/74 (32%), Positives = 35/74 (47%), Gaps = 1/74 (1%) Frame = -2 Query: 626 VGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCEHD-EGVTCLAWLG 450 V +L GH ++ C + TGS D T+ IW + + ST + E V C+A L Sbjct: 221 VQTLEGHAQNVSCASFHPELPIIITGSEDGTVRIWHSSTYRLESTLNYGMERVWCVASLR 280 Query: 449 SSRYVASGCIDGMV 408 S VA G +G + Sbjct: 281 GSNNVALGYDEGSI 294
>COPB2_BOVIN (P35605) Coatomer subunit beta' (Beta'-coat protein) (Beta'-COP)| (p102) Length = 905 Score = 62.0 bits (149), Expect = 2e-09 Identities = 38/127 (29%), Positives = 66/127 (51%), Gaps = 4/127 (3%) Frame = -2 Query: 611 GHTNSIECIGISSR-YNWVATGSIDRTLIIWDLARQAIRSTCE-HDEGVTCLAWL--GSS 444 GHT+ + I I+ + N A+ S+DRT+ +W L + T E H++GV C+ + G Sbjct: 139 GHTHYVMQIVINPKDNNQFASASLDRTIKVWQLGSSSPNFTLEGHEKGVNCIDYYSGGDK 198 Query: 443 RYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFDIS 264 Y+ SG D +V+IWD + +T GH V + + I++ S D + R++ S Sbjct: 199 PYLISGADDRLVKIWDYQNKTCVQTLEGHAQNVSCASFHPELPIIITGSEDGTVRIWHSS 258 Query: 263 MFK*EKS 243 ++ E + Sbjct: 259 TYRLEST 265 Score = 45.8 bits (107), Expect = 1e-04 Identities = 34/130 (26%), Positives = 63/130 (48%), Gaps = 3/130 (2%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYN--WVATGSIDRTLIIWDLARQAIRSTC 489 ++ + + S +L GH + CI S + ++ +G+ DR + IWD + T Sbjct: 165 TIKVWQLGSSSPNFTLEGHEKGVNCIDYYSGGDKPYLISGADDRLVKIWDYQNKTCVQTL 224 Query: 488 E-HDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNS 312 E H + V+C ++ + +G DG VRIW S + L T + + V +A S G++ Sbjct: 225 EGHAQNVSCASFHPELPIIITGSEDGTVRIWHSSTYRLESTLNYGMERVWCVA-SLRGSN 283 Query: 311 IVSVSTDKSA 282 V++ D+ + Sbjct: 284 NVALGYDEGS 293 Score = 44.7 bits (104), Expect = 3e-04 Identities = 23/106 (21%), Positives = 52/106 (49%), Gaps = 3/106 (2%) Frame = -2 Query: 575 SRYNWVATGSIDRTLIIWDL-ARQAIRSTCEHDEGVTCLAWLGSSRYVASGCIDGMVRIW 399 +R NWV TG+ D + +++ + + H + + C+A + ++ + D ++++W Sbjct: 66 ARKNWVVTGADDMQIRVFNYNTLERVHMFEAHSDYIRCIAVHPTQPFILTSSDDMLIKLW 125 Query: 398 D-SLSGDLARTFSGHRDVVQSLAVS-ADGNSIVSVSTDKSARVFDI 267 D ++ F GH V + ++ D N S S D++ +V+ + Sbjct: 126 DWDKKWSCSQVFEGHTHYVMQIVINPKDNNQFASASLDRTIKVWQL 171 Score = 39.3 bits (90), Expect = 0.011 Identities = 24/74 (32%), Positives = 35/74 (47%), Gaps = 1/74 (1%) Frame = -2 Query: 626 VGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCEHD-EGVTCLAWLG 450 V +L GH ++ C + TGS D T+ IW + + ST + E V C+A L Sbjct: 221 VQTLEGHAQNVSCASFHPELPIIITGSEDGTVRIWHSSTYRLESTLNYGMERVWCVASLR 280 Query: 449 SSRYVASGCIDGMV 408 S VA G +G + Sbjct: 281 GSNNVALGYDEGSI 294
>PWP2_HUMAN (Q15269) Periodic tryptophan protein 2 homolog| Length = 919 Score = 62.0 bits (149), Expect = 2e-09 Identities = 36/136 (26%), Positives = 68/136 (50%), Gaps = 2/136 (1%) Frame = -2 Query: 656 HIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDR-TLIIWDLARQA-IRSTCEH 483 H+ + ++ SL SI + I+S +W+A G L++W+ ++ + H Sbjct: 313 HLHELPEFNLIHSLSISDQSIASVAINSSGDWIAFGCSGLGQLLVWEWQSESYVLKQQGH 372 Query: 482 DEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVS 303 + LA+ +Y+ +G DG V++W++LSG TF+ H V + +A G +V+ Sbjct: 373 FNSMVALAYSPDGQYIVTGGDDGKVKVWNTLSGFCFVTFTEHSSGVTGVTFTATGYVVVT 432 Query: 302 VSTDKSARVFDISMFK 255 S D + R FD+ ++ Sbjct: 433 SSMDGTVRAFDLHRYR 448 Score = 42.0 bits (97), Expect = 0.002 Identities = 32/127 (25%), Positives = 59/127 (46%), Gaps = 3/127 (2%) Frame = -2 Query: 638 SGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLAR-QAIRS-TCEHDEGVTC 465 SG + H++ + + ++ V T S+D T+ +DL R + R+ T +C Sbjct: 404 SGFCFVTFTEHSSGVTGVTFTATGYVVVTSSMDGTVRAFDLHRYRNFRTFTSPRPTQFSC 463 Query: 464 LAWLGSSRYVASGCIDGM-VRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDK 288 +A S V++G D + +W +G L SGH + L + + + S S DK Sbjct: 464 VAVDASGEIVSAGAQDSFEIFVWSMQTGRLLDVLSGHEGPISGLCFNPMKSVLASASWDK 523 Query: 287 SARVFDI 267 + R++D+ Sbjct: 524 TVRLWDM 530 Score = 32.3 bits (72), Expect = 1.3 Identities = 26/152 (17%), Positives = 59/152 (38%), Gaps = 21/152 (13%) Frame = -2 Query: 659 VHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQ-AIRSTCEH 483 + + S+ +G+++ L GH I + + + +A+ S D+T+ +WD+ + T Sbjct: 483 IFVWSMQTGRLLDVLSGHEGPISGLCFNPMKSVLASASWDKTVRLWDMFDSWRTKETLAL 542 Query: 482 DEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDV--------------- 348 + + +A ++ + WD + + G D+ Sbjct: 543 TSDALAVTFRPDGAELAVATLNSQITFWDPENAVQTGSIEGRHDLKTGRKELDKITAKHA 602 Query: 347 -----VQSLAVSADGNSIVSVSTDKSARVFDI 267 +L SADG+SI++ K ++ + Sbjct: 603 AKGKAFTALCYSADGHSILAGGMSKFVCIYHV 634
>GBLP_CHLRE (P25387) Guanine nucleotide-binding protein beta subunit-like| protein Length = 318 Score = 61.6 bits (148), Expect = 2e-09 Identities = 39/128 (30%), Positives = 65/128 (50%), Gaps = 11/128 (8%) Frame = -2 Query: 620 SLVGHTNSIECIG--ISSRYNWVATGSIDRTLIIWDL---------ARQAIRSTCEHDEG 474 +L GHTN + I + N + + S D+++++W+L AR+A+R H Sbjct: 10 TLKGHTNWVTAIATPLDPSSNTLLSASRDKSVLVWELERSESNYGYARKALRG---HSHF 66 Query: 473 VTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVST 294 V + ++ +G DG +R+WD +G R F GH V S+A S D IVS S Sbjct: 67 VQDVVISSDGQFCLTGSWDGTLRLWDLNTGTTTRRFVGHTKDVLSVAFSVDNRQIVSGSR 126 Query: 293 DKSARVFD 270 DK+ ++++ Sbjct: 127 DKTIKLWN 134 Score = 60.5 bits (145), Expect = 4e-09 Identities = 35/138 (25%), Positives = 68/138 (49%), Gaps = 5/138 (3%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCE- 486 ++ + +N+G VGHT + + S + +GS D+T+ +W+ + + E Sbjct: 87 TLRLWDLNTGTTTRRFVGHTKDVLSVAFSVDNRQIVSGSRDKTIKLWNTLGECKYTIGEP 146 Query: 485 --HDEGVTCLAW--LGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADG 318 H E V+C+ + + ++ + SG D MV++W+ + L GH V ++ VS DG Sbjct: 147 EGHTEWVSCVRFSPMTTNPIIVSGGWDKMVKVWNLTNCKLKNNLVGHHGYVNTVTVSPDG 206 Query: 317 NSIVSVSTDKSARVFDIS 264 + S D A ++D++ Sbjct: 207 SLCASGGKDGIAMLWDLA 224 Score = 52.0 bits (123), Expect = 2e-06 Identities = 42/145 (28%), Positives = 70/145 (48%), Gaps = 6/145 (4%) Frame = -2 Query: 641 NSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDL-ARQAIRSTCEHDEGVTC 465 N G +L GH++ ++ + ISS + TGS D TL +WDL R H + V Sbjct: 52 NYGYARKALRGHSHFVQDVVISSDGQFCLTGSWDGTLRLWDLNTGTTTRRFVGHTKDVLS 111 Query: 464 LAWLGSSRYVASGCIDGMVRIWDSLSGDLARTF---SGHRDVVQSLAVS--ADGNSIVSV 300 +A+ +R + SG D +++W++L G+ T GH + V + S IVS Sbjct: 112 VAFSVDNRQIVSGSRDKTIKLWNTL-GECKYTIGEPEGHTEWVSCVRFSPMTTNPIIVSG 170 Query: 299 STDKSARVFDISMFK*EKS*QQQHG 225 DK +V++++ K + + HG Sbjct: 171 GWDKMVKVWNLTNCKLKNNLVGHHG 195 Score = 48.9 bits (115), Expect = 1e-05 Identities = 37/140 (26%), Positives = 66/140 (47%), Gaps = 9/140 (6%) Frame = -2 Query: 659 VHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCEHD 480 V + ++ + ++ +LVGH + + +S + A+G D ++WDLA + + Sbjct: 176 VKVWNLTNCKLKNNLVGHHGYVNTVTVSPDGSLCASGGKDGIAMLWDLAEGKRLYSLDAG 235 Query: 479 EGVTCLAWLGSSRYVASGCIDGMVRIWD----SLSGDLARTFSGHRDVVQ-----SLAVS 327 + + CL + +RY ++IWD S+ DL F+ Q SLA S Sbjct: 236 DVIHCLCF-SPNRYWLCAATQSSIKIWDLESKSIVDDLRPEFNITSKKAQVPYCVSLAWS 294 Query: 326 ADGNSIVSVSTDKSARVFDI 267 ADG+++ S TD RV+ + Sbjct: 295 ADGSTLYSGYTDGQIRVWAV 314
>MET30_YEAST (P39014) F-box protein MET30 (Methionine requiring protein 30) (E3| ubiquitin ligase complex SCF(Met30) subunit MET30) Length = 640 Score = 61.6 bits (148), Expect = 2e-09 Identities = 38/116 (32%), Positives = 63/116 (54%), Gaps = 1/116 (0%) Frame = -2 Query: 611 GHTNSIECIGISSRYNWVATGSIDRTLIIWDL-ARQAIRSTCEHDEGVTCLAWLGSSRYV 435 GH + + + + Y + TGS D T+ IWDL + IR H +GV L + R + Sbjct: 300 GHMDGV--LTLQFNYRLLFTGSYDSTIGIWDLFTGKLIRRLSGHSDGVKTLYF--DDRKL 355 Query: 434 ASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFDI 267 +G +D +R+W+ ++G+ T+ GH D V L+V + IVS S DK+ +V+ + Sbjct: 356 ITGSLDKTIRVWNYITGECISTYRGHSDSV--LSVDSYQKVIVSGSADKTVKVWHV 409 Score = 47.4 bits (111), Expect = 4e-05 Identities = 27/127 (21%), Positives = 61/127 (48%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCEH 483 ++ + + +G+ + + GH++S+ + + S + +GS D+T+ +W + + + H Sbjct: 363 TIRVWNYITGECISTYRGHSDSV--LSVDSYQKVIVSGSADKTVKVWHVESRTCYTLRGH 420 Query: 482 DEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVS 303 E V C+ S S D +R+WD + + F GH VQ + + + + Sbjct: 421 TEWVNCVKLHPKSFSCFSCSDDTTIRMWDIRTNSCLKVFRGHVGQVQKI-IPLTIKDVEN 479 Query: 302 VSTDKSA 282 ++TD ++ Sbjct: 480 LATDNTS 486 Score = 42.7 bits (99), Expect = 0.001 Identities = 27/85 (31%), Positives = 43/85 (50%) Frame = -2 Query: 524 WDLARQAIRSTCEHDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVV 345 W I+ H +GV L + + R + +G D + IWD +G L R SGH D V Sbjct: 288 WRKGHCRIQEFKGHMDGVLTLQF--NYRLLFTGSYDSTIGIWDLFTGKLIRRLSGHSDGV 345 Query: 344 QSLAVSADGNSIVSVSTDKSARVFD 270 ++L D +++ S DK+ RV++ Sbjct: 346 KTLYF--DDRKLITGSLDKTIRVWN 368 Score = 42.4 bits (98), Expect = 0.001 Identities = 23/65 (35%), Positives = 36/65 (55%), Gaps = 1/65 (1%) Frame = -2 Query: 545 IDRTLIIWDLAR-QAIRSTCEHDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLART 369 +D T+ +WD+ + IR+ H EGV +A + + SG DG +++WD SG T Sbjct: 530 LDNTIKLWDVKTGKCIRTQFGHVEGVWDIA--ADNFRIISGSHDGSIKVWDLQSGKCMHT 587 Query: 368 FSGHR 354 F+G R Sbjct: 588 FNGRR 592 Score = 35.4 bits (80), Expect = 0.15 Identities = 20/56 (35%), Positives = 31/56 (55%) Frame = -2 Query: 422 IDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFDISMFK 255 +D +++WD +G RT GH + V +A AD I+S S D S +V+D+ K Sbjct: 530 LDNTIKLWDVKTGKCIRTQFGHVEGVWDIA--ADNFRIISGSHDGSIKVWDLQSGK 583
>GBLP_BIOGL (Q93134) Guanine nucleotide-binding protein beta subunit 2-like 1| (Receptor of activated protein kinase C) (RACK) Length = 316 Score = 61.6 bits (148), Expect = 2e-09 Identities = 39/125 (31%), Positives = 63/125 (50%), Gaps = 7/125 (5%) Frame = -2 Query: 623 GSLVGHTNSIECIGISSRY-NWVATGSIDRTLIIWDLARQAI------RSTCEHDEGVTC 465 G+L GH + I + +Y + + + S D++LI+W L R +S H V+ Sbjct: 9 GTLQGHGGWVTQIATTPQYPDMILSASRDKSLIVWRLTRDESSYGVPQKSLHGHGHFVSD 68 Query: 464 LAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKS 285 + ++ SG D +R+WD +G R F GH V S+A SAD IVS S DK+ Sbjct: 69 VILSSDGQFALSGSWDHTLRLWDLSTGQTTRRFVGHTKDVLSVAFSADNRQIVSGSRDKT 128 Query: 284 ARVFD 270 ++++ Sbjct: 129 IKLWN 133 Score = 58.9 bits (141), Expect = 1e-08 Identities = 32/138 (23%), Positives = 70/138 (50%), Gaps = 5/138 (3%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWD---LARQAIRST 492 ++ + +++GQ VGHT + + S+ + +GS D+T+ +W+ + + I+ Sbjct: 86 TLRLWDLSTGQTTRRFVGHTKDVLSVAFSADNRQIVSGSRDKTIKLWNTLGVCKYTIQDD 145 Query: 491 CEHDEGVTCLAWLGSSR--YVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADG 318 C H + +C+ + +++ + S D +V++W+ + L GH V ++ VS DG Sbjct: 146 C-HTDWTSCVRFSPNTQNPIIVSSGWDRLVKVWNLTNCKLKTNHYGHTGYVNTVTVSPDG 204 Query: 317 NSIVSVSTDKSARVFDIS 264 + S D A ++D++ Sbjct: 205 SLCASGGKDSQAMLWDLN 222 Score = 40.0 bits (92), Expect = 0.006 Identities = 37/128 (28%), Positives = 55/128 (42%), Gaps = 11/128 (8%) Frame = -2 Query: 611 GHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCEHDEGVTCLAWLGSSRY-- 438 GHT + + +S + A+G D ++WDL T + +RY Sbjct: 190 GHTGYVNTVTVSPDGSLCASGGKDSQAMLWDLNEGKHLYTLDGAGDTINALCFSPNRYWL 249 Query: 437 -VASGCIDGMVRIWD--------SLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKS 285 VASG ++IWD L ++ T S SLA SADG ++ + TDK Sbjct: 250 CVASG---PSIKIWDLEGKVVVDELKPEVMGTTS-KAPTCLSLAWSADGQTLFAGYTDKL 305 Query: 284 ARVFDISM 261 RV+ +SM Sbjct: 306 IRVWQVSM 313
>FBW1A_HUMAN (Q9Y297) F-box/WD-repeat protein 1A (F-box and WD-repeats protein| beta-TrCP) (E3RSIkappaB) (pIkappaBalpha-E3 receptor subunit) Length = 605 Score = 61.6 bits (148), Expect = 2e-09 Identities = 35/118 (29%), Positives = 60/118 (50%), Gaps = 1/118 (0%) Frame = -2 Query: 617 LVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLAR-QAIRSTCEHDEGVTCLAWLGSSR 441 LVGH ++ + +Y + + S DRT+ +W+ + + +R+ H G+ CL + R Sbjct: 422 LVGHRAAVNVVDFDDKY--IVSASGDRTIKVWNTSTCEFVRTLNGHKRGIACLQY--RDR 477 Query: 440 YVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFDI 267 V SG D +R+WD G R GH ++V+ + D IVS + D +V+D+ Sbjct: 478 LVVSGSSDNTIRLWDIECGACLRVLEGHEELVR--CIRFDNKRIVSGAYDGKIKVWDL 533 Score = 45.4 bits (106), Expect = 1e-04 Identities = 29/100 (29%), Positives = 49/100 (49%), Gaps = 1/100 (1%) Frame = -2 Query: 560 VATGSIDRTLIIWDL-ARQAIRSTCEHDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSG 384 + +G D T+ IWD + R H V CL + R + +G D VR+WD +G Sbjct: 316 IVSGLRDNTIKIWDKNTLECKRILTGHTGSVLCLQY--DERVIITGSSDSTVRVWDVNTG 373 Query: 383 DLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFDIS 264 ++ T H + V L + + +V+ S D+S V+D++ Sbjct: 374 EMLNTLIHHCEAV--LHLRFNNGMMVTCSKDRSIAVWDMA 411
>GBB1_RAT (P54311) Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta| subunit 1 (Transducin beta chain 1) Length = 339 Score = 61.6 bits (148), Expect = 2e-09 Identities = 38/134 (28%), Positives = 62/134 (46%), Gaps = 3/134 (2%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCEH 483 S + + G + GH + I I N ATGS D T ++DL T H Sbjct: 206 SAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTYSH 265 Query: 482 DE---GVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNS 312 D G+T +++ S R + +G D +WD+L D A +GH + V L V+ DG + Sbjct: 266 DNIICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDNRVSCLGVTDDGMA 325 Query: 311 IVSVSTDKSARVFD 270 + + S D ++++ Sbjct: 326 VATGSWDSFLKIWN 339 Score = 61.6 bits (148), Expect = 2e-09 Identities = 35/123 (28%), Positives = 56/123 (45%), Gaps = 1/123 (0%) Frame = -2 Query: 632 QVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLAR-QAIRSTCEHDEGVTCLAW 456 +V L GHT + C N + T S D T +WD+ Q + H V L+ Sbjct: 133 RVSRELAGHTGYLSCCRFLDD-NQIVTSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSL 191 Query: 455 LGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARV 276 +R SG D ++WD G +TF+GH + ++ +GN+ + S D + R+ Sbjct: 192 APDTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRL 251 Query: 275 FDI 267 FD+ Sbjct: 252 FDL 254 Score = 38.1 bits (87), Expect = 0.024 Identities = 39/164 (23%), Positives = 59/164 (35%), Gaps = 46/164 (28%) Frame = -2 Query: 620 SLVGHTNSIECIGISSRYNWVATGSIDRTLIIWD-LARQAIRSTCEHDEGVTCLAWLGSS 444 +L GH I + + + + S D LIIWD + + V A+ S Sbjct: 49 TLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSG 108 Query: 443 RYVASGCID------------GMVRI---------------------------------W 399 YVA G +D G VR+ W Sbjct: 109 NYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVTSSGDTTCALW 168 Query: 398 DSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFDI 267 D +G TF+GH V SL+++ D VS + D SA+++D+ Sbjct: 169 DIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDV 212 Score = 30.8 bits (68), Expect = 3.8 Identities = 22/96 (22%), Positives = 38/96 (39%) Frame = -2 Query: 554 TGSIDRTLIIWDLARQAIRSTCEHDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLA 375 T +ID I R+ +R H + + W SR + S DG + IWDS + + Sbjct: 33 TNNIDPVGRIQMRTRRTLRG---HLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKV 89 Query: 374 RTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFDI 267 V + A + GN + D ++++ Sbjct: 90 HAIPLRSSWVMTCAYAPSGNYVACGGLDNICSIYNL 125
>GBB1_MOUSE (P62874) Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta| subunit 1 (Transducin beta chain 1) Length = 339 Score = 61.6 bits (148), Expect = 2e-09 Identities = 38/134 (28%), Positives = 62/134 (46%), Gaps = 3/134 (2%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCEH 483 S + + G + GH + I I N ATGS D T ++DL T H Sbjct: 206 SAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTYSH 265 Query: 482 DE---GVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNS 312 D G+T +++ S R + +G D +WD+L D A +GH + V L V+ DG + Sbjct: 266 DNIICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDNRVSCLGVTDDGMA 325 Query: 311 IVSVSTDKSARVFD 270 + + S D ++++ Sbjct: 326 VATGSWDSFLKIWN 339 Score = 61.6 bits (148), Expect = 2e-09 Identities = 35/123 (28%), Positives = 56/123 (45%), Gaps = 1/123 (0%) Frame = -2 Query: 632 QVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLAR-QAIRSTCEHDEGVTCLAW 456 +V L GHT + C N + T S D T +WD+ Q + H V L+ Sbjct: 133 RVSRELAGHTGYLSCCRFLDD-NQIVTSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSL 191 Query: 455 LGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARV 276 +R SG D ++WD G +TF+GH + ++ +GN+ + S D + R+ Sbjct: 192 APDTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRL 251 Query: 275 FDI 267 FD+ Sbjct: 252 FDL 254 Score = 38.1 bits (87), Expect = 0.024 Identities = 39/164 (23%), Positives = 59/164 (35%), Gaps = 46/164 (28%) Frame = -2 Query: 620 SLVGHTNSIECIGISSRYNWVATGSIDRTLIIWD-LARQAIRSTCEHDEGVTCLAWLGSS 444 +L GH I + + + + S D LIIWD + + V A+ S Sbjct: 49 TLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSG 108 Query: 443 RYVASGCID------------GMVRI---------------------------------W 399 YVA G +D G VR+ W Sbjct: 109 NYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVTSSGDTTCALW 168 Query: 398 DSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFDI 267 D +G TF+GH V SL+++ D VS + D SA+++D+ Sbjct: 169 DIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDV 212 Score = 30.8 bits (68), Expect = 3.8 Identities = 22/96 (22%), Positives = 38/96 (39%) Frame = -2 Query: 554 TGSIDRTLIIWDLARQAIRSTCEHDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLA 375 T +ID I R+ +R H + + W SR + S DG + IWDS + + Sbjct: 33 TNNIDPVGRIQMRTRRTLRG---HLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKV 89 Query: 374 RTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFDI 267 V + A + GN + D ++++ Sbjct: 90 HAIPLRSSWVMTCAYAPSGNYVACGGLDNICSIYNL 125
>GBB1_HUMAN (P62873) Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta| subunit 1 (Transducin beta chain 1) Length = 339 Score = 61.6 bits (148), Expect = 2e-09 Identities = 38/134 (28%), Positives = 62/134 (46%), Gaps = 3/134 (2%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCEH 483 S + + G + GH + I I N ATGS D T ++DL T H Sbjct: 206 SAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTYSH 265 Query: 482 DE---GVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNS 312 D G+T +++ S R + +G D +WD+L D A +GH + V L V+ DG + Sbjct: 266 DNIICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDNRVSCLGVTDDGMA 325 Query: 311 IVSVSTDKSARVFD 270 + + S D ++++ Sbjct: 326 VATGSWDSFLKIWN 339 Score = 61.6 bits (148), Expect = 2e-09 Identities = 35/123 (28%), Positives = 56/123 (45%), Gaps = 1/123 (0%) Frame = -2 Query: 632 QVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLAR-QAIRSTCEHDEGVTCLAW 456 +V L GHT + C N + T S D T +WD+ Q + H V L+ Sbjct: 133 RVSRELAGHTGYLSCCRFLDD-NQIVTSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSL 191 Query: 455 LGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARV 276 +R SG D ++WD G +TF+GH + ++ +GN+ + S D + R+ Sbjct: 192 APDTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRL 251 Query: 275 FDI 267 FD+ Sbjct: 252 FDL 254 Score = 38.1 bits (87), Expect = 0.024 Identities = 39/164 (23%), Positives = 59/164 (35%), Gaps = 46/164 (28%) Frame = -2 Query: 620 SLVGHTNSIECIGISSRYNWVATGSIDRTLIIWD-LARQAIRSTCEHDEGVTCLAWLGSS 444 +L GH I + + + + S D LIIWD + + V A+ S Sbjct: 49 TLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSG 108 Query: 443 RYVASGCID------------GMVRI---------------------------------W 399 YVA G +D G VR+ W Sbjct: 109 NYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVTSSGDTTCALW 168 Query: 398 DSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFDI 267 D +G TF+GH V SL+++ D VS + D SA+++D+ Sbjct: 169 DIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDV 212 Score = 30.8 bits (68), Expect = 3.8 Identities = 22/96 (22%), Positives = 38/96 (39%) Frame = -2 Query: 554 TGSIDRTLIIWDLARQAIRSTCEHDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLA 375 T +ID I R+ +R H + + W SR + S DG + IWDS + + Sbjct: 33 TNNIDPVGRIQMRTRRTLRG---HLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKV 89 Query: 374 RTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFDI 267 V + A + GN + D ++++ Sbjct: 90 HAIPLRSSWVMTCAYAPSGNYVACGGLDNICSIYNL 125
>GBB1_CANFA (P62872) Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta| subunit 1 (Transducin beta chain 1) Length = 339 Score = 61.6 bits (148), Expect = 2e-09 Identities = 38/134 (28%), Positives = 62/134 (46%), Gaps = 3/134 (2%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCEH 483 S + + G + GH + I I N ATGS D T ++DL T H Sbjct: 206 SAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTYSH 265 Query: 482 DE---GVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNS 312 D G+T +++ S R + +G D +WD+L D A +GH + V L V+ DG + Sbjct: 266 DNIICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDNRVSCLGVTDDGMA 325 Query: 311 IVSVSTDKSARVFD 270 + + S D ++++ Sbjct: 326 VATGSWDSFLKIWN 339 Score = 61.6 bits (148), Expect = 2e-09 Identities = 35/123 (28%), Positives = 56/123 (45%), Gaps = 1/123 (0%) Frame = -2 Query: 632 QVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLAR-QAIRSTCEHDEGVTCLAW 456 +V L GHT + C N + T S D T +WD+ Q + H V L+ Sbjct: 133 RVSRELAGHTGYLSCCRFLDD-NQIVTSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSL 191 Query: 455 LGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARV 276 +R SG D ++WD G +TF+GH + ++ +GN+ + S D + R+ Sbjct: 192 APDTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRL 251 Query: 275 FDI 267 FD+ Sbjct: 252 FDL 254 Score = 38.1 bits (87), Expect = 0.024 Identities = 39/164 (23%), Positives = 59/164 (35%), Gaps = 46/164 (28%) Frame = -2 Query: 620 SLVGHTNSIECIGISSRYNWVATGSIDRTLIIWD-LARQAIRSTCEHDEGVTCLAWLGSS 444 +L GH I + + + + S D LIIWD + + V A+ S Sbjct: 49 TLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSG 108 Query: 443 RYVASGCID------------GMVRI---------------------------------W 399 YVA G +D G VR+ W Sbjct: 109 NYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVTSSGDTTCALW 168 Query: 398 DSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFDI 267 D +G TF+GH V SL+++ D VS + D SA+++D+ Sbjct: 169 DIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDV 212 Score = 30.8 bits (68), Expect = 3.8 Identities = 22/96 (22%), Positives = 38/96 (39%) Frame = -2 Query: 554 TGSIDRTLIIWDLARQAIRSTCEHDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLA 375 T +ID I R+ +R H + + W SR + S DG + IWDS + + Sbjct: 33 TNNIDPVGRIQMRTRRTLRG---HLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKV 89 Query: 374 RTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFDI 267 V + A + GN + D ++++ Sbjct: 90 HAIPLRSSWVMTCAYAPSGNYVACGGLDNICSIYNL 125
>GBB1_BOVIN (P62871) Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta| subunit 1 (Transducin beta chain 1) Length = 339 Score = 61.6 bits (148), Expect = 2e-09 Identities = 38/134 (28%), Positives = 62/134 (46%), Gaps = 3/134 (2%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCEH 483 S + + G + GH + I I N ATGS D T ++DL T H Sbjct: 206 SAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTYSH 265 Query: 482 DE---GVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNS 312 D G+T +++ S R + +G D +WD+L D A +GH + V L V+ DG + Sbjct: 266 DNIICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDNRVSCLGVTDDGMA 325 Query: 311 IVSVSTDKSARVFD 270 + + S D ++++ Sbjct: 326 VATGSWDSFLKIWN 339 Score = 61.6 bits (148), Expect = 2e-09 Identities = 35/123 (28%), Positives = 56/123 (45%), Gaps = 1/123 (0%) Frame = -2 Query: 632 QVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLAR-QAIRSTCEHDEGVTCLAW 456 +V L GHT + C N + T S D T +WD+ Q + H V L+ Sbjct: 133 RVSRELAGHTGYLSCCRFLDD-NQIVTSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSL 191 Query: 455 LGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARV 276 +R SG D ++WD G +TF+GH + ++ +GN+ + S D + R+ Sbjct: 192 APDTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRL 251 Query: 275 FDI 267 FD+ Sbjct: 252 FDL 254 Score = 38.1 bits (87), Expect = 0.024 Identities = 39/164 (23%), Positives = 59/164 (35%), Gaps = 46/164 (28%) Frame = -2 Query: 620 SLVGHTNSIECIGISSRYNWVATGSIDRTLIIWD-LARQAIRSTCEHDEGVTCLAWLGSS 444 +L GH I + + + + S D LIIWD + + V A+ S Sbjct: 49 TLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSG 108 Query: 443 RYVASGCID------------GMVRI---------------------------------W 399 YVA G +D G VR+ W Sbjct: 109 NYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVTSSGDTTCALW 168 Query: 398 DSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFDI 267 D +G TF+GH V SL+++ D VS + D SA+++D+ Sbjct: 169 DIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDV 212 Score = 30.8 bits (68), Expect = 3.8 Identities = 22/96 (22%), Positives = 38/96 (39%) Frame = -2 Query: 554 TGSIDRTLIIWDLARQAIRSTCEHDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLA 375 T +ID I R+ +R H + + W SR + S DG + IWDS + + Sbjct: 33 TNNIDPVGRIQMRTRRTLRG---HLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKV 89 Query: 374 RTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFDI 267 V + A + GN + D ++++ Sbjct: 90 HAIPLRSSWVMTCAYAPSGNYVACGGLDNICSIYNL 125
>TRCB_XENLA (Q91854) Beta-TrCP (Beta-transducin repeat-containing protein)| Length = 518 Score = 61.6 bits (148), Expect = 2e-09 Identities = 35/118 (29%), Positives = 60/118 (50%), Gaps = 1/118 (0%) Frame = -2 Query: 617 LVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLAR-QAIRSTCEHDEGVTCLAWLGSSR 441 LVGH ++ + +Y + + S DRT+ +W+ + + +R+ H G+ CL + R Sbjct: 351 LVGHRAAVNVVDFDDKY--IVSASGDRTIKVWNTSTCEFVRTLNGHKRGIACLQY--RDR 406 Query: 440 YVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFDI 267 V SG D +R+WD G R GH ++V+ + D IVS + D +V+D+ Sbjct: 407 LVVSGSSDNTIRLWDIECGACLRVLEGHEELVR--CIRFDNKRIVSGAYDGKIKVWDL 462 Score = 45.4 bits (106), Expect = 1e-04 Identities = 29/100 (29%), Positives = 49/100 (49%), Gaps = 1/100 (1%) Frame = -2 Query: 560 VATGSIDRTLIIWDL-ARQAIRSTCEHDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSG 384 + +G D T+ IWD + R H V CL + R + +G D VR+WD +G Sbjct: 245 IVSGLRDNTIKIWDKNTLECKRVLMGHTGSVLCLQY--DERVIITGSSDSTVRVWDVNTG 302 Query: 383 DLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFDIS 264 ++ T H + V L + + +V+ S D+S V+D++ Sbjct: 303 EMLNTLIHHCEAV--LHLRFNNGMMVTCSKDRSIAVWDMA 340
>GBLP_LEIIN (P62884) Guanine nucleotide-binding protein beta subunit-like| protein (Antigen LACK) (LiP36) (p36Li) Length = 312 Score = 61.6 bits (148), Expect = 2e-09 Identities = 40/143 (27%), Positives = 74/143 (51%), Gaps = 5/143 (3%) Frame = -2 Query: 656 HIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLAR-QAIRSTCEHD 480 H V + G L GHT + C+ ++ ++ T S DR++ +WDL Q R +H Sbjct: 48 HSVDSDYGLPSHRLEGHTGFVSCVSLAHATDYALTASWDRSIRMWDLRNGQCQRKFLKHT 107 Query: 479 EGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTF--SGHRDVVQSL--AVSADGNS 312 + V +A+ R + S D ++R+W +++G+ F GH D V S+ + S + Sbjct: 108 KDVLAVAFSPDDRLIVSAGRDNVIRVW-NVAGECMHEFLRDGHEDWVSSICFSPSLEHPI 166 Query: 311 IVSVSTDKSARVFDISMFK*EKS 243 +VS S D + +V++++ K E++ Sbjct: 167 VVSGSWDNTIKVWNVNGGKCERT 189 Score = 58.5 bits (140), Expect = 2e-08 Identities = 32/137 (23%), Positives = 65/137 (47%), Gaps = 4/137 (2%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCE- 486 S+ + + +GQ + HT + + S + + D + +W++A + + Sbjct: 88 SIRMWDLRNGQCQRKFLKHTKDVLAVAFSPDDRLIVSAGRDNVIRVWNVAGECMHEFLRD 147 Query: 485 -HDEGVTCLAWLGSSRY--VASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGN 315 H++ V+ + + S + V SG D +++W+ G RT GH + V ++ VS DG+ Sbjct: 148 GHEDWVSSICFSPSLEHPIVVSGSWDNTIKVWNVNGGKCERTLKGHSNYVSTVTVSPDGS 207 Query: 314 SIVSVSTDKSARVFDIS 264 S D +A ++D+S Sbjct: 208 LCASGGKDGAALLWDLS 224 Score = 45.8 bits (107), Expect = 1e-04 Identities = 37/135 (27%), Positives = 57/135 (42%), Gaps = 15/135 (11%) Frame = -2 Query: 623 GSLVGH---TNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCEHDEG------- 474 G L GH S+ C + Y V + S D T I W R + + D G Sbjct: 5 GHLKGHRGWVTSLACPQQAGSYIKVVSTSRDGTAISWKANPD--RHSVDSDYGLPSHRLE 62 Query: 473 -----VTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSI 309 V+C++ ++ Y + D +R+WD +G R F H V ++A S D I Sbjct: 63 GHTGFVSCVSLAHATDYALTASWDRSIRMWDLRNGQCQRKFLKHTKDVLAVAFSPDDRLI 122 Query: 308 VSVSTDKSARVFDIS 264 VS D RV++++ Sbjct: 123 VSAGRDNVIRVWNVA 137 Score = 33.1 bits (74), Expect = 0.76 Identities = 29/118 (24%), Positives = 53/118 (44%), Gaps = 3/118 (2%) Frame = -2 Query: 611 GHTNSIE--CIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCE-HDEGVTCLAWLGSSR 441 GH + + C S + V +GS D T+ +W++ T + H V+ + Sbjct: 148 GHEDWVSSICFSPSLEHPIVVSGSWDNTIKVWNVNGGKCERTLKGHSNYVSTVTVSPDGS 207 Query: 440 YVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFDI 267 ASG DG +WD +G+ + + Q +A S + + V+T++S V+D+ Sbjct: 208 LCASGGKDGAALLWDLSTGEQLFKINVESPINQ-IAFSPN-RFWMCVATERSLSVYDL 263
>GBLP_LEICH (P62883) Guanine nucleotide-binding protein beta subunit-like| protein (Antigen LACK) Length = 312 Score = 61.6 bits (148), Expect = 2e-09 Identities = 40/143 (27%), Positives = 74/143 (51%), Gaps = 5/143 (3%) Frame = -2 Query: 656 HIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLAR-QAIRSTCEHD 480 H V + G L GHT + C+ ++ ++ T S DR++ +WDL Q R +H Sbjct: 48 HSVDSDYGLPSHRLEGHTGFVSCVSLAHATDYALTASWDRSIRMWDLRNGQCQRKFLKHT 107 Query: 479 EGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTF--SGHRDVVQSL--AVSADGNS 312 + V +A+ R + S D ++R+W +++G+ F GH D V S+ + S + Sbjct: 108 KDVLAVAFSPDDRLIVSAGRDNVIRVW-NVAGECMHEFLRDGHEDWVSSICFSPSLEHPI 166 Query: 311 IVSVSTDKSARVFDISMFK*EKS 243 +VS S D + +V++++ K E++ Sbjct: 167 VVSGSWDNTIKVWNVNGGKCERT 189 Score = 58.5 bits (140), Expect = 2e-08 Identities = 32/137 (23%), Positives = 65/137 (47%), Gaps = 4/137 (2%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCE- 486 S+ + + +GQ + HT + + S + + D + +W++A + + Sbjct: 88 SIRMWDLRNGQCQRKFLKHTKDVLAVAFSPDDRLIVSAGRDNVIRVWNVAGECMHEFLRD 147 Query: 485 -HDEGVTCLAWLGSSRY--VASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGN 315 H++ V+ + + S + V SG D +++W+ G RT GH + V ++ VS DG+ Sbjct: 148 GHEDWVSSICFSPSLEHPIVVSGSWDNTIKVWNVNGGKCERTLKGHSNYVSTVTVSPDGS 207 Query: 314 SIVSVSTDKSARVFDIS 264 S D +A ++D+S Sbjct: 208 LCASGGKDGAALLWDLS 224 Score = 45.8 bits (107), Expect = 1e-04 Identities = 37/135 (27%), Positives = 57/135 (42%), Gaps = 15/135 (11%) Frame = -2 Query: 623 GSLVGH---TNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCEHDEG------- 474 G L GH S+ C + Y V + S D T I W R + + D G Sbjct: 5 GHLKGHRGWVTSLACPQQAGSYIKVVSTSRDGTAISWKANPD--RHSVDSDYGLPSHRLE 62 Query: 473 -----VTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSI 309 V+C++ ++ Y + D +R+WD +G R F H V ++A S D I Sbjct: 63 GHTGFVSCVSLAHATDYALTASWDRSIRMWDLRNGQCQRKFLKHTKDVLAVAFSPDDRLI 122 Query: 308 VSVSTDKSARVFDIS 264 VS D RV++++ Sbjct: 123 VSAGRDNVIRVWNVA 137 Score = 33.1 bits (74), Expect = 0.76 Identities = 29/118 (24%), Positives = 53/118 (44%), Gaps = 3/118 (2%) Frame = -2 Query: 611 GHTNSIE--CIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCE-HDEGVTCLAWLGSSR 441 GH + + C S + V +GS D T+ +W++ T + H V+ + Sbjct: 148 GHEDWVSSICFSPSLEHPIVVSGSWDNTIKVWNVNGGKCERTLKGHSNYVSTVTVSPDGS 207 Query: 440 YVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFDI 267 ASG DG +WD +G+ + + Q +A S + + V+T++S V+D+ Sbjct: 208 LCASGGKDGAALLWDLSTGEQLFKINVESPINQ-IAFSPN-RFWMCVATERSLSVYDL 263
>GBLP_LEIMA (Q25306) Guanine nucleotide-binding protein beta subunit-like| protein (Antigen LACK) Length = 312 Score = 61.2 bits (147), Expect = 3e-09 Identities = 40/143 (27%), Positives = 74/143 (51%), Gaps = 5/143 (3%) Frame = -2 Query: 656 HIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLAR-QAIRSTCEHD 480 H V + G L GHT + C+ ++ ++ T S DR++ +WDL Q R +H Sbjct: 48 HSVDSDYGLPNHRLEGHTGFVSCVSLAHATDYALTASWDRSIRMWDLRNGQCQRKFLKHT 107 Query: 479 EGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTF--SGHRDVVQSL--AVSADGNS 312 + V +A+ R + S D ++R+W +++G+ F GH D V S+ + S + Sbjct: 108 KDVLAVAFSPDDRLIVSAGRDNVIRVW-NVAGECMHEFLRDGHEDWVSSICFSPSLEHPI 166 Query: 311 IVSVSTDKSARVFDISMFK*EKS 243 +VS S D + +V++++ K E++ Sbjct: 167 VVSGSWDNTIKVWNVNGGKCERT 189 Score = 58.5 bits (140), Expect = 2e-08 Identities = 32/137 (23%), Positives = 65/137 (47%), Gaps = 4/137 (2%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCE- 486 S+ + + +GQ + HT + + S + + D + +W++A + + Sbjct: 88 SIRMWDLRNGQCQRKFLKHTKDVLAVAFSPDDRLIVSAGRDNVIRVWNVAGECMHEFLRD 147 Query: 485 -HDEGVTCLAWLGSSRY--VASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGN 315 H++ V+ + + S + V SG D +++W+ G RT GH + V ++ VS DG+ Sbjct: 148 GHEDWVSSICFSPSLEHPIVVSGSWDNTIKVWNVNGGKCERTLKGHSNYVSTVTVSPDGS 207 Query: 314 SIVSVSTDKSARVFDIS 264 S D +A ++D+S Sbjct: 208 LCASGGKDGAALLWDLS 224 Score = 46.6 bits (109), Expect = 7e-05 Identities = 37/135 (27%), Positives = 58/135 (42%), Gaps = 15/135 (11%) Frame = -2 Query: 623 GSLVGH---TNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCEHDEG------- 474 G L GH S+ C + Y V + S D T+I W R + + D G Sbjct: 5 GHLKGHRGWVTSLACPQQAGSYIKVVSTSRDGTVISWKANPD--RHSVDSDYGLPNHRLE 62 Query: 473 -----VTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSI 309 V+C++ ++ Y + D +R+WD +G R F H V ++A S D I Sbjct: 63 GHTGFVSCVSLAHATDYALTASWDRSIRMWDLRNGQCQRKFLKHTKDVLAVAFSPDDRLI 122 Query: 308 VSVSTDKSARVFDIS 264 VS D RV++++ Sbjct: 123 VSAGRDNVIRVWNVA 137 Score = 32.3 bits (72), Expect = 1.3 Identities = 28/119 (23%), Positives = 51/119 (42%), Gaps = 4/119 (3%) Frame = -2 Query: 611 GHTNSIE--CIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCE-HDEGVTCLAWLGSSR 441 GH + + C S + V +GS D T+ +W++ T + H V+ + Sbjct: 148 GHEDWVSSICFSPSLEHPIVVSGSWDNTIKVWNVNGGKCERTLKGHSNYVSTVTVSPDGS 207 Query: 440 YVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSI-VSVSTDKSARVFDI 267 ASG DG +WD +G+ + + Q + N + V+T++S V+D+ Sbjct: 208 LCASGGKDGAALLWDLSTGEQLFKINVESPINQ---IGFSPNRFWMCVATERSLSVYDL 263 Score = 30.0 bits (66), Expect = 6.5 Identities = 18/70 (25%), Positives = 32/70 (45%), Gaps = 4/70 (5%) Frame = -2 Query: 596 IECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCEHDEG----VTCLAWLGSSRYVAS 429 I IG S W+ + +R+L ++DL +A+ + D +AW + S Sbjct: 238 INQIGFSPNRFWMCVAT-ERSLSVYDLESKAVIAELTPDGAKPSECISIAWSADGNTLYS 296 Query: 428 GCIDGMVRIW 399 G D ++R+W Sbjct: 297 GHKDNLIRVW 306
>FBW1B_HUMAN (Q9UKB1) F-box/WD-repeat protein 11 (F-box/WD-repeat protein 1B)| (F-box and WD-repeats protein beta-TrCP2) Length = 542 Score = 61.2 bits (147), Expect = 3e-09 Identities = 35/118 (29%), Positives = 59/118 (50%), Gaps = 1/118 (0%) Frame = -2 Query: 617 LVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLAR-QAIRSTCEHDEGVTCLAWLGSSR 441 LVGH ++ + +Y + + S DRT+ +W + + +R+ H G+ CL + R Sbjct: 359 LVGHRAAVNVVDFDDKY--IVSASGDRTIKVWSTSTCEFVRTLNGHKRGIACLQY--RDR 414 Query: 440 YVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFDI 267 V SG D +R+WD G R GH ++V+ + D IVS + D +V+D+ Sbjct: 415 LVVSGSSDNTIRLWDIECGACLRVLEGHEELVR--CIRFDNKRIVSGAYDGKIKVWDL 470 Score = 46.6 bits (109), Expect = 7e-05 Identities = 28/100 (28%), Positives = 50/100 (50%), Gaps = 1/100 (1%) Frame = -2 Query: 560 VATGSIDRTLIIWD-LARQAIRSTCEHDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSG 384 + +G D ++ IWD + + ++ H V CL + R + +G D VR+WD +G Sbjct: 253 IISGLRDNSIKIWDKTSLECLKVLTGHTGSVLCLQY--DERVIVTGSSDSTVRVWDVNTG 310 Query: 383 DLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFDIS 264 ++ T H + V L S +V+ S D+S V+D++ Sbjct: 311 EVLNTLIHHNEAVLHLRFS--NGLMVTCSKDRSIAVWDMA 348
>PWP2_YEAST (P25635) Periodic tryptophan protein 2 (U3 small nucleolar| RNA-associated protein 1) (U3 snoRNA-associated protein 1) Length = 923 Score = 61.2 bits (147), Expect = 3e-09 Identities = 38/134 (28%), Positives = 63/134 (47%), Gaps = 3/134 (2%) Frame = -2 Query: 659 VHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCEHD 480 + + I SG + + HT+S+ + + R + + S+D T+ WDL R T Sbjct: 369 IKVWDITSGFCLATFEEHTSSVTAVQFAKRGQVMFSSSLDGTVRAWDLIRYRNFRTFTGT 428 Query: 479 EGV--TCLAWLGSSRYVASGCIDGM-VRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSI 309 E + CLA S V +G +D + +W +G L SGH V L+ S + + + Sbjct: 429 ERIQFNCLAVDPSGEVVCAGSLDNFDIHVWSVQTGQLLDALSGHEGPVSCLSFSQENSVL 488 Query: 308 VSVSTDKSARVFDI 267 S S DK+ R++ I Sbjct: 489 ASASWDKTIRIWSI 502 Score = 47.8 bits (112), Expect = 3e-05 Identities = 36/120 (30%), Positives = 54/120 (45%), Gaps = 2/120 (1%) Frame = -2 Query: 611 GHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCE-HDEGVTCLAWLGSSRYV 435 GH +S + S + V T S D + +WD+ +T E H VT + + + + Sbjct: 343 GHFDSTNSLAYSPDGSRVVTASEDGKIKVWDITSGFCLATFEEHTSSVTAVQFAKRGQVM 402 Query: 434 ASGCIDGMVRIWDSLSGDLARTFSG-HRDVVQSLAVSADGNSIVSVSTDKSARVFDISMF 258 S +DG VR WD + RTF+G R LAV G + + S D FDI ++ Sbjct: 403 FSSSLDGTVRAWDLIRYRNFRTFTGTERIQFNCLAVDPSGEVVCAGSLDN----FDIHVW 458 Score = 44.7 bits (104), Expect = 3e-04 Identities = 31/152 (20%), Positives = 63/152 (41%), Gaps = 21/152 (13%) Frame = -2 Query: 659 VHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDL-ARQAIRSTCEH 483 +H+ S+ +GQ++ +L GH + C+ S + +A+ S D+T+ IW + R E Sbjct: 455 IHVWSVQTGQLLDALSGHEGPVSCLSFSQENSVLASASWDKTIRIWSIFGRSQQVEPIEV 514 Query: 482 DEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQ------------- 342 V L+ + VA + G + I++ +D++ Sbjct: 515 YSDVLALSMRPDGKEVAVSTLKGQISIFNIEDAKQVGNIDCRKDIISGRFNQDRFTAKNS 574 Query: 341 -------SLAVSADGNSIVSVSTDKSARVFDI 267 ++ S DG +IV+ + S ++D+ Sbjct: 575 ERSKFFTTIHYSFDGMAIVAGGNNNSICLYDV 606 Score = 43.9 bits (102), Expect = 4e-04 Identities = 27/77 (35%), Positives = 40/77 (51%), Gaps = 3/77 (3%) Frame = -2 Query: 485 HDEGVTCLAWLGSSRYVASGCIDGMVRIW--DSLSGDLART-FSGHRDVVQSLAVSADGN 315 H + +T L W SR++ + D +IW DS +LA T F+GHRD V S D Sbjct: 145 HFQDITSLTWSQDSRFILTTSKDLSAKIWSVDSEEKNLAATTFNGHRDYVMGAFFSHDQE 204 Query: 314 SIVSVSTDKSARVFDIS 264 I +VS D + V++ + Sbjct: 205 KIYTVSKDGAVFVWEFT 221 Score = 33.5 bits (75), Expect = 0.58 Identities = 20/50 (40%), Positives = 28/50 (56%) Frame = -2 Query: 413 MVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFDIS 264 +V W S S L + GH D SLA S DG+ +V+ S D +V+DI+ Sbjct: 328 LVYEWQSESYILKQ--QGHFDSTNSLAYSPDGSRVVTASEDGKIKVWDIT 375
>SPG16_MOUSE (Q8K450) Sperm-associated antigen 16 protein (PF20 protein homolog)| Length = 639 Score = 61.2 bits (147), Expect = 3e-09 Identities = 42/138 (30%), Positives = 64/138 (46%), Gaps = 1/138 (0%) Frame = -2 Query: 653 IVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCE-HDE 477 +V + G V+ + GHT+ + + +AT S D T+ +WDL + T E H+ Sbjct: 386 MVGLPQGNVLLTGSGHTDWLSGCCFHPSGSKLATSSGDSTIKLWDLNKGECTLTLEGHNH 445 Query: 476 GVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVS 297 V W +VAS +D +IWD S T GH D V S+ N +++ S Sbjct: 446 AVWSCTWHSCGDFVASASLDMTSKIWDVNSERCRYTLYGHTDSVNSIEFFPFSNILLTAS 505 Query: 296 TDKSARVFDISMFK*EKS 243 DK+ V+D K E+S Sbjct: 506 ADKTLSVWDARTGKCEQS 523 Score = 50.8 bits (120), Expect = 4e-06 Identities = 30/132 (22%), Positives = 61/132 (46%), Gaps = 1/132 (0%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTC-E 486 ++ + +N G+ +L GH +++ S ++VA+ S+D T IWD+ + R T Sbjct: 425 TIKLWDLNKGECTLTLEGHNHAVWSCTWHSCGDFVASASLDMTSKIWDVNSERCRYTLYG 484 Query: 485 HDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIV 306 H + V + + S + + D + +WD+ +G ++ GH V + G+ I Sbjct: 485 HTDSVNSIEFFPFSNILLTASADKTLSVWDARTGKCEQSLYGHMHSVNDATFTPRGHIIA 544 Query: 305 SVSTDKSARVFD 270 S +++D Sbjct: 545 SCDARGVTKLWD 556 Score = 31.6 bits (70), Expect = 2.2 Identities = 28/123 (22%), Positives = 54/123 (43%), Gaps = 1/123 (0%) Frame = -2 Query: 638 SGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQ-AIRSTCEHDEGVTCL 462 +G+ SL GH +S+ + R + +A+ +WD + I S + Sbjct: 517 TGKCEQSLYGHMHSVNDATFTPRGHIIASCDARGVTKLWDFRKLIPIVSIDVGPSSGNEV 576 Query: 461 AWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSA 282 + S R +A +G++ + D SG + + GH V S+ S G ++ S +D + Sbjct: 577 NFDQSGRVLAQASANGIIHLLDLKSGQIHK-LVGHESEVHSVVFSHLGENLYSGGSDGTI 635 Query: 281 RVF 273 R++ Sbjct: 636 RLW 638 Score = 29.6 bits (65), Expect = 8.4 Identities = 16/74 (21%), Positives = 35/74 (47%) Frame = -2 Query: 485 HDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIV 306 H+ V+C+ Y+ S D + ++ G++ T SGH D + G+ + Sbjct: 359 HELPVSCIVMHPCRDYLISCSEDRLWKMVGLPQGNVLLTGSGHTDWLSGCCFHPSGSKLA 418 Query: 305 SVSTDKSARVFDIS 264 + S D + +++D++ Sbjct: 419 TSSGDSTIKLWDLN 432
>PRP46_KLULA (Q6CKE8) Pre-mRNA-splicing factor PRP46 (Pre-mRNA-processing| protein 46) Length = 434 Score = 60.8 bits (146), Expect = 3e-09 Identities = 39/133 (29%), Positives = 66/133 (49%), Gaps = 1/133 (0%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQ-AIRSTCE 486 ++ I + +G++ +L+GH S+ I IS R+ ++ + S D+ + WDL R AIR Sbjct: 146 TIKIWDLAAGKLKITLIGHVMSVRDIAISKRHPYMFSASEDKLVKCWDLERNTAIRDFHG 205 Query: 485 HDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIV 306 H GV + S +A+ D +VR+WD S GH+ + + I+ Sbjct: 206 HLSGVHTVDVHPSLDIIATAGRDAVVRLWDIRSRSEIMVLPGHKSPINKVKCLPVDPQII 265 Query: 305 SVSTDKSARVFDI 267 S S D + R++DI Sbjct: 266 SCSGDATVRLWDI 278 Score = 57.0 bits (136), Expect = 5e-08 Identities = 38/117 (32%), Positives = 54/117 (46%), Gaps = 2/117 (1%) Frame = -2 Query: 611 GHTNSIECIGISSRYN-WVATGSIDRTLIIWDLARQAIRST-CEHDEGVTCLAWLGSSRY 438 GHT + C+ + N W ATGS D T+ IWDLA ++ T H V +A Y Sbjct: 120 GHTGWVRCVCVDPVDNEWFATGSNDTTIKIWDLAAGKLKITLIGHVMSVRDIAISKRHPY 179 Query: 437 VASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFDI 267 + S D +V+ WD R F GH V ++ V + I + D R++DI Sbjct: 180 MFSASEDKLVKCWDLERNTAIRDFHGHLSGVHTVDVHPSLDIIATAGRDAVVRLWDI 236 Score = 42.4 bits (98), Expect = 0.001 Identities = 25/108 (23%), Positives = 48/108 (44%), Gaps = 1/108 (0%) Frame = -2 Query: 611 GHTNSIECIGISSRYNWVATGSIDRTLIIWDL-ARQAIRSTCEHDEGVTCLAWLGSSRYV 435 GH + + + + + +AT D + +WD+ +R I H + + L + Sbjct: 205 GHLSGVHTVDVHPSLDIIATAGRDAVVRLWDIRSRSEIMVLPGHKSPINKVKCLPVDPQI 264 Query: 434 ASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTD 291 S D VR+WD ++G ++ + H ++ L + S SVST+ Sbjct: 265 ISCSGDATVRLWDIIAGKASKVLTHHSRNIRDLTLHPAEFSFASVSTN 312
>TBL1R_MOUSE (Q8BHJ5) F-box-like/WD-repeat protein TBL1XR1 (Transducin beta-like| 1X-related protein 1) (Nuclear receptor corepressor/HDAC3 complex subunit TBLR1) (TBL1-related protein 1) Length = 514 Score = 60.8 bits (146), Expect = 3e-09 Identities = 36/140 (25%), Positives = 64/140 (45%), Gaps = 10/140 (7%) Frame = -2 Query: 659 VHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQ-AIRSTCEH 483 +H+ + + + + GHTN + I N +A+ S D TL IW + + + H Sbjct: 331 IHVCKLGQDRPIKTFQGHTNEVNAIKWDPTGNLLASCSDDMTLKIWSMKQDNCVHDLQAH 390 Query: 482 DEGVTCLAWL---------GSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAV 330 ++ + + W ++ +AS D VR+WD G T + H++ V S+A Sbjct: 391 NKEIYTIKWSPTGPGTNNPNANLMLASASFDSTVRLWDVDRGICIHTLTKHQEPVYSVAF 450 Query: 329 SADGNSIVSVSTDKSARVFD 270 S DG + S S DK +++ Sbjct: 451 SPDGRYLASGSFDKCVHIWN 470 Score = 53.9 bits (128), Expect = 4e-07 Identities = 42/142 (29%), Positives = 65/142 (45%), Gaps = 15/142 (10%) Frame = -2 Query: 650 VSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLAR-------QAIRST 492 V I S + V L GH + + + + +A+GS D T IW+L+ Q + Sbjct: 155 VEIPSNKAV-VLRGHESEVFICAWNPVSDLLASGSGDSTARIWNLSENSTSGPTQLVLRH 213 Query: 491 CEHDEG--------VTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSL 336 C + G VT L W +A+G DG RIW + G+LA T H+ + +L Sbjct: 214 CIREGGQDVPSNKDVTSLDWNSEGTLLATGSYDGFARIW-TKDGNLASTLGQHKGPIFAL 272 Query: 335 AVSADGNSIVSVSTDKSARVFD 270 + GN I+S DK+ ++D Sbjct: 273 KWNKKGNFILSAGVDKTTIIWD 294 Score = 52.4 bits (124), Expect = 1e-06 Identities = 30/99 (30%), Positives = 55/99 (55%), Gaps = 1/99 (1%) Frame = -2 Query: 560 VATGSIDRTLIIWDLARQ-AIRSTCEHDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSG 384 +A+ S D T+ +WD+ R I + +H E V +A+ RY+ASG D V IW++ +G Sbjct: 415 LASASFDSTVRLWDVDRGICIHTLTKHQEPVYSVAFSPDGRYLASGSFDKCVHIWNTQTG 474 Query: 383 DLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFDI 267 L ++ G + + + +A G+ + + ++D S V D+ Sbjct: 475 ALVHSYRGTGGIFE-VCWNAAGDKVGASASDGSVCVLDL 512 Score = 40.8 bits (94), Expect = 0.004 Identities = 27/124 (21%), Positives = 55/124 (44%), Gaps = 1/124 (0%) Frame = -2 Query: 635 GQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDL-ARQAIRSTCEHDEGVTCLA 459 G + +L H I + + + N++ + +D+T IIWD +A + H + Sbjct: 256 GNLASTLGQHKGPIFALKWNKKGNFILSAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVD 315 Query: 458 WLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSAR 279 W ++ + AS D + + +TF GH + V ++ GN + S S D + + Sbjct: 316 WQSNNTF-ASCSTDMCIHVCKLGQDRPIKTFQGHTNEVNAIKWDPTGNLLASCSDDMTLK 374 Query: 278 VFDI 267 ++ + Sbjct: 375 IWSM 378 Score = 38.1 bits (87), Expect = 0.024 Identities = 29/119 (24%), Positives = 46/119 (38%), Gaps = 3/119 (2%) Frame = -2 Query: 623 GSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCEHDEGVTCLAWLGSS 444 G V + + +S +ATGS D IW + +H + L W Sbjct: 219 GQDVPSNKDVTSLDWNSEGTLLATGSYDGFARIWTKDGNLASTLGQHKGPIFALKWNKKG 278 Query: 443 RYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSAD---GNSIVSVSTDKSARV 276 ++ S +D IWD+ +G+ + F H + A+ D N+ S STD V Sbjct: 279 NFILSAGVDKTTIIWDAHTGEAKQQFPFH----SAPALDVDWQSNNTFASCSTDMCIHV 333 Score = 35.8 bits (81), Expect = 0.12 Identities = 19/89 (21%), Positives = 40/89 (44%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCEH 483 +V + ++ G + +L H + + S ++A+GS D+ + IW+ A+ + Sbjct: 423 TVRLWDVDRGICIHTLTKHQEPVYSVAFSPDGRYLASGSFDKCVHIWNTQTGALVHSYRG 482 Query: 482 DEGVTCLAWLGSSRYVASGCIDGMVRIWD 396 G+ + W + V + DG V + D Sbjct: 483 TGGIFEVCWNAAGDKVGASASDGSVCVLD 511
>TBL1R_HUMAN (Q9BZK7) F-box-like/WD-repeat protein TBL1XR1 (Transducin beta-like| 1X-related protein 1) (Nuclear receptor corepressor/HDAC3 complex subunit TBLR1) (TBL1-related protein 1) Length = 514 Score = 60.8 bits (146), Expect = 3e-09 Identities = 36/140 (25%), Positives = 64/140 (45%), Gaps = 10/140 (7%) Frame = -2 Query: 659 VHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQ-AIRSTCEH 483 +H+ + + + + GHTN + I N +A+ S D TL IW + + + H Sbjct: 331 IHVCKLGQDRPIKTFQGHTNEVNAIKWDPTGNLLASCSDDMTLKIWSMKQDNCVHDLQAH 390 Query: 482 DEGVTCLAWL---------GSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAV 330 ++ + + W ++ +AS D VR+WD G T + H++ V S+A Sbjct: 391 NKEIYTIKWSPTGPGTNNPNANLMLASASFDSTVRLWDVDRGICIHTLTKHQEPVYSVAF 450 Query: 329 SADGNSIVSVSTDKSARVFD 270 S DG + S S DK +++ Sbjct: 451 SPDGRYLASGSFDKCVHIWN 470 Score = 53.5 bits (127), Expect = 5e-07 Identities = 38/131 (29%), Positives = 60/131 (45%), Gaps = 15/131 (11%) Frame = -2 Query: 617 LVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLAR-------QAIRSTCEHDEG----- 474 L GH + + + + +A+GS D T IW+L+ Q + C + G Sbjct: 165 LRGHESEVFICAWNPVSDLLASGSGDSTARIWNLSENSTSGSTQLVLRHCIREGGQDVPS 224 Query: 473 ---VTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVS 303 VT L W +A+G DG RIW + G+LA T H+ + +L + GN I+S Sbjct: 225 NKDVTSLDWNSEGTLLATGSYDGFARIW-TKDGNLASTLGQHKGPIFALKWNKKGNFILS 283 Query: 302 VSTDKSARVFD 270 DK+ ++D Sbjct: 284 AGVDKTTIIWD 294 Score = 52.4 bits (124), Expect = 1e-06 Identities = 30/99 (30%), Positives = 55/99 (55%), Gaps = 1/99 (1%) Frame = -2 Query: 560 VATGSIDRTLIIWDLARQ-AIRSTCEHDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSG 384 +A+ S D T+ +WD+ R I + +H E V +A+ RY+ASG D V IW++ +G Sbjct: 415 LASASFDSTVRLWDVDRGICIHTLTKHQEPVYSVAFSPDGRYLASGSFDKCVHIWNTQTG 474 Query: 383 DLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFDI 267 L ++ G + + + +A G+ + + ++D S V D+ Sbjct: 475 ALVHSYRGTGGIFE-VCWNAAGDKVGASASDGSVCVLDL 512 Score = 40.8 bits (94), Expect = 0.004 Identities = 27/124 (21%), Positives = 55/124 (44%), Gaps = 1/124 (0%) Frame = -2 Query: 635 GQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDL-ARQAIRSTCEHDEGVTCLA 459 G + +L H I + + + N++ + +D+T IIWD +A + H + Sbjct: 256 GNLASTLGQHKGPIFALKWNKKGNFILSAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVD 315 Query: 458 WLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSAR 279 W ++ + AS D + + +TF GH + V ++ GN + S S D + + Sbjct: 316 WQSNNTF-ASCSTDMCIHVCKLGQDRPIKTFQGHTNEVNAIKWDPTGNLLASCSDDMTLK 374 Query: 278 VFDI 267 ++ + Sbjct: 375 IWSM 378 Score = 38.1 bits (87), Expect = 0.024 Identities = 29/119 (24%), Positives = 46/119 (38%), Gaps = 3/119 (2%) Frame = -2 Query: 623 GSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCEHDEGVTCLAWLGSS 444 G V + + +S +ATGS D IW + +H + L W Sbjct: 219 GQDVPSNKDVTSLDWNSEGTLLATGSYDGFARIWTKDGNLASTLGQHKGPIFALKWNKKG 278 Query: 443 RYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSAD---GNSIVSVSTDKSARV 276 ++ S +D IWD+ +G+ + F H + A+ D N+ S STD V Sbjct: 279 NFILSAGVDKTTIIWDAHTGEAKQQFPFH----SAPALDVDWQSNNTFASCSTDMCIHV 333 Score = 35.8 bits (81), Expect = 0.12 Identities = 19/89 (21%), Positives = 40/89 (44%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCEH 483 +V + ++ G + +L H + + S ++A+GS D+ + IW+ A+ + Sbjct: 423 TVRLWDVDRGICIHTLTKHQEPVYSVAFSPDGRYLASGSFDKCVHIWNTQTGALVHSYRG 482 Query: 482 DEGVTCLAWLGSSRYVASGCIDGMVRIWD 396 G+ + W + V + DG V + D Sbjct: 483 TGGIFEVCWNAAGDKVGASASDGSVCVLD 511
>APAF_HUMAN (O14727) Apoptotic protease-activating factor 1 (Apaf-1)| Length = 1248 Score = 60.5 bits (145), Expect = 4e-09 Identities = 34/143 (23%), Positives = 69/143 (48%), Gaps = 3/143 (2%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWD-LARQAIRSTCE 486 ++ + +G+ + + H + + C S+ ++AT S+D+ + IW+ + + + + E Sbjct: 638 TLQVFKAETGEKLLEIKAHEDEVLCCAFSTDDRFIATCSVDKKVKIWNSMTGELVHTYDE 697 Query: 485 HDEGVTCLAWLGSSRYV--ASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNS 312 H E V C + SS ++ A+G D +++WD + T GH + V S D Sbjct: 698 HSEQVNCCHFTNSSHHLLLATGSSDCFLKLWDLNQKECRNTMFGHTNSVNHCRFSPDDKL 757 Query: 311 IVSVSTDKSARVFDISMFK*EKS 243 + S S D + +++D + KS Sbjct: 758 LASCSADGTLKLWDATSANERKS 780 Score = 48.5 bits (114), Expect = 2e-05 Identities = 30/134 (22%), Positives = 62/134 (46%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCEH 483 ++ I+ + + ++ S H ++ I ++ + + S D + +W+ H Sbjct: 984 AIEILELVNNRIFQSRFQHKKTVWHIQFTADEKTLISSSDDAEIQVWNWQLDKCIFLRGH 1043 Query: 482 DEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVS 303 E V L +SR + S DG V++W+ ++G+ + F H+ V S +S D S Sbjct: 1044 QETVKDFRLLKNSRLL-SWSFDGTVKVWNIITGNKEKDFVCHQGTVLSCDISHDATKFSS 1102 Query: 302 VSTDKSARVFDISM 261 S DK+A+++ + Sbjct: 1103 TSADKTAKIWSFDL 1116 Score = 45.1 bits (105), Expect = 2e-04 Identities = 23/89 (25%), Positives = 47/89 (52%), Gaps = 1/89 (1%) Frame = -2 Query: 608 HTNSIECIGISSRYNWVATGSIDRTLIIWDLAR-QAIRSTCEHDEGVTCLAWLGSSRYVA 432 HT+++ S +A+ D+TL ++ + + H++ V C A+ R++A Sbjct: 614 HTDAVYHACFSEDGQRIASCGADKTLQVFKAETGEKLLEIKAHEDEVLCCAFSTDDRFIA 673 Query: 431 SGCIDGMVRIWDSLSGDLARTFSGHRDVV 345 + +D V+IW+S++G+L T+ H + V Sbjct: 674 TCSVDKKVKIWNSMTGELVHTYDEHSEQV 702 Score = 37.0 bits (84), Expect = 0.053 Identities = 32/129 (24%), Positives = 54/129 (41%), Gaps = 9/129 (6%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDL-ARQAIRSTCE 486 +V + +I +G V H ++ IS ++ S D+T IW + Sbjct: 1066 TVKVWNIITGNKEKDFVCHQGTVLSCDISHDATKFSSTSADKTAKIWSFDLLLPLHELRG 1125 Query: 485 HDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLART--------FSGHRDVVQSLAV 330 H+ V C A+ S +A+G +G +RIW+ +G+L + H V L Sbjct: 1126 HNGCVRCSAFSVDSTLLATGDDNGEIRIWNVSNGELLHLCAPLSEEGAATHGGWVTDLCF 1185 Query: 329 SADGNSIVS 303 S DG ++S Sbjct: 1186 SPDGKMLIS 1194 Score = 29.6 bits (65), Expect = 8.4 Identities = 16/73 (21%), Positives = 37/73 (50%) Frame = -2 Query: 473 VTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVST 294 V+C +Y+A G +G + I + ++ + ++ H+ V + +AD +++S S Sbjct: 964 VSCCCLSPHLQYIAFGDENGAIEILELVNNRIFQSRFQHKKTVWHIQFTADEKTLISSSD 1023 Query: 293 DKSARVFDISMFK 255 D +V++ + K Sbjct: 1024 DAEIQVWNWQLDK 1036
>WD51B_PONPY (Q5RD06) WD-repeat protein 51B| Length = 451 Score = 60.5 bits (145), Expect = 4e-09 Identities = 43/167 (25%), Positives = 74/167 (44%), Gaps = 3/167 (1%) Frame = -2 Query: 608 HTNSIECIGISSRYNWVATGSIDRTLIIWDLARQA-IRSTCEHDEGVTCLAWLGSSRYVA 432 HT + + S+ ++AT S D+++ +W + RQ + S H V C + R + Sbjct: 101 HTAPVRSVDFSADGQFLATASEDKSIKVWSMYRQRFLYSLYRHTHWVRCAKFSPDGRLIV 160 Query: 431 SGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFDISMFK* 252 S D ++IWD+ + FS + + G I S +D++ +V+D+ + K Sbjct: 161 SCSEDKTIKIWDTTNKQCVNNFSDSVGFANFVDFNPSGTCIASAGSDQTVKVWDVRVNK- 219 Query: 251 EKS*QQQHG*FGWSFWPVKSGGL--LSLYGQELYLQACSHHGALKTL 117 QH + V SGG+ +S + + YL S G LK L Sbjct: 220 ----LLQH-------YQVHSGGVNCISFHPSDNYLVTASSDGTLKIL 255 Score = 48.5 bits (114), Expect = 2e-05 Identities = 26/91 (28%), Positives = 45/91 (49%), Gaps = 1/91 (1%) Frame = -2 Query: 560 VATGSIDRTLIIWDL-ARQAIRSTCEHDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSG 384 +A+ D+T+ +WD+ + ++ H GV C+++ S Y+ + DG ++I D L G Sbjct: 201 IASAGSDQTVKVWDVRVNKLLQHYQVHSGGVNCISFHPSDNYLVTASSDGTLKILDLLEG 260 Query: 383 DLARTFSGHRDVVQSLAVSADGNSIVSVSTD 291 L T GH V +++ S G S D Sbjct: 261 RLIYTLQGHTGPVFTVSFSKGGELFASGGAD 291 Score = 47.8 bits (112), Expect = 3e-05 Identities = 33/116 (28%), Positives = 52/116 (44%), Gaps = 1/116 (0%) Frame = -2 Query: 611 GHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQA-IRSTCEHDEGVTCLAWLGSSRYV 435 GH +I + +S +AT S D L++W+ A H + VT + + + Sbjct: 16 GHKAAITSLDLSPNGKQLATASWDTFLMLWNFKPHARAYRYVGHKDVVTSVQFSPHGNLL 75 Query: 434 ASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFDI 267 AS D VR+W F H V+S+ SADG + + S DKS +V+ + Sbjct: 76 ASASRDRTVRLWIPDKRGKFSEFKAHTAPVRSVDFSADGQFLATASEDKSIKVWSM 131 Score = 47.0 bits (110), Expect = 5e-05 Identities = 30/133 (22%), Positives = 61/133 (45%), Gaps = 1/133 (0%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLA-RQAIRSTCE 486 S+ + S+ + + SL HT+ + C S + + S D+T+ IWD +Q + + + Sbjct: 125 SIKVWSMYRQRFLYSLYRHTHWVRCAKFSPDGRLIVSCSEDKTIKIWDTTNKQCVNNFSD 184 Query: 485 HDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIV 306 + + S +AS D V++WD L + + H V ++ N +V Sbjct: 185 SVGFANFVDFNPSGTCIASAGSDQTVKVWDVRVNKLLQHYQVHSGGVNCISFHPSDNYLV 244 Query: 305 SVSTDKSARVFDI 267 + S+D + ++ D+ Sbjct: 245 TASSDGTLKILDL 257 Score = 46.2 bits (108), Expect = 9e-05 Identities = 29/116 (25%), Positives = 54/116 (46%), Gaps = 1/116 (0%) Frame = -2 Query: 614 VGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCE-HDEGVTCLAWLGSSRY 438 VGH + + + S N +A+ S DRT+ +W ++ S + H V + + ++ Sbjct: 57 VGHKDVVTSVQFSPHGNLLASASRDRTVRLWIPDKRGKFSEFKAHTAPVRSVDFSADGQF 116 Query: 437 VASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFD 270 +A+ D +++W + H V+ S DG IVS S DK+ +++D Sbjct: 117 LATASEDKSIKVWSMYRQRFLYSLYRHTHWVRCAKFSPDGRLIVSCSEDKTIKIWD 172
>TB1RA_XENLA (Q7SZM9) F-box-like/WD-repeat-containing protein TBL1XR1-A| (Transducin beta-like 1X-related protein 1-A) (Nuclear receptor corepressor/HDAC3 complex subunit TBLR1-A) (TBL1-related protein 1-A) (xTBLR1) Length = 519 Score = 60.5 bits (145), Expect = 4e-09 Identities = 36/140 (25%), Positives = 63/140 (45%), Gaps = 10/140 (7%) Frame = -2 Query: 659 VHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQA-IRSTCEH 483 +H+ + + + + GHTN + I N +A+ S D TL IW + + H Sbjct: 336 IHVCKLGQDRPIKTFQGHTNEVNAIKWDPTGNLLASCSDDMTLKIWSMKHDTCVHDLQAH 395 Query: 482 DEGVTCLAWL---------GSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAV 330 ++ + + W ++ +AS D VR+WD G T + H++ V S+A Sbjct: 396 NKEIYTIKWSPTGPGTNNPNANLMLASASFDSTVRLWDVDRGICIHTLTKHQEPVYSVAF 455 Query: 329 SADGNSIVSVSTDKSARVFD 270 S DG + S S DK +++ Sbjct: 456 SPDGRYLASGSFDKCVHIWN 475 Score = 53.9 bits (128), Expect = 4e-07 Identities = 42/142 (29%), Positives = 65/142 (45%), Gaps = 15/142 (10%) Frame = -2 Query: 650 VSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLAR-------QAIRST 492 V I S + V L GH + + + + +A+GS D T IW+L+ Q + Sbjct: 160 VEIPSSKAV-VLRGHESEVFICAWNPVSDLLASGSGDSTARIWNLSENSTSGSTQLVLRH 218 Query: 491 CEHDEG--------VTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSL 336 C + G VT L W +A+G DG RIW + G+LA T H+ + +L Sbjct: 219 CIREGGQDVPSNKDVTSLDWNSEGTLLATGSYDGFARIW-TKDGNLASTLGQHKGPIFAL 277 Query: 335 AVSADGNSIVSVSTDKSARVFD 270 + GN I+S DK+ ++D Sbjct: 278 KWNKKGNFILSAGVDKTTIIWD 299 Score = 52.4 bits (124), Expect = 1e-06 Identities = 30/99 (30%), Positives = 55/99 (55%), Gaps = 1/99 (1%) Frame = -2 Query: 560 VATGSIDRTLIIWDLARQ-AIRSTCEHDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSG 384 +A+ S D T+ +WD+ R I + +H E V +A+ RY+ASG D V IW++ +G Sbjct: 420 LASASFDSTVRLWDVDRGICIHTLTKHQEPVYSVAFSPDGRYLASGSFDKCVHIWNTQTG 479 Query: 383 DLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFDI 267 L ++ G + + + +A G+ + + ++D S V D+ Sbjct: 480 ALVHSYRGTGGIFE-VCWNAAGDKVGASASDGSVCVLDL 517 Score = 40.8 bits (94), Expect = 0.004 Identities = 27/124 (21%), Positives = 55/124 (44%), Gaps = 1/124 (0%) Frame = -2 Query: 635 GQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDL-ARQAIRSTCEHDEGVTCLA 459 G + +L H I + + + N++ + +D+T IIWD +A + H + Sbjct: 261 GNLASTLGQHKGPIFALKWNKKGNFILSAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVD 320 Query: 458 WLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSAR 279 W ++ + AS D + + +TF GH + V ++ GN + S S D + + Sbjct: 321 WQSNNTF-ASCSTDMCIHVCKLGQDRPIKTFQGHTNEVNAIKWDPTGNLLASCSDDMTLK 379 Query: 278 VFDI 267 ++ + Sbjct: 380 IWSM 383 Score = 38.1 bits (87), Expect = 0.024 Identities = 29/119 (24%), Positives = 46/119 (38%), Gaps = 3/119 (2%) Frame = -2 Query: 623 GSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCEHDEGVTCLAWLGSS 444 G V + + +S +ATGS D IW + +H + L W Sbjct: 224 GQDVPSNKDVTSLDWNSEGTLLATGSYDGFARIWTKDGNLASTLGQHKGPIFALKWNKKG 283 Query: 443 RYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSAD---GNSIVSVSTDKSARV 276 ++ S +D IWD+ +G+ + F H + A+ D N+ S STD V Sbjct: 284 NFILSAGVDKTTIIWDAHTGEAKQQFPFH----SAPALDVDWQSNNTFASCSTDMCIHV 338 Score = 35.8 bits (81), Expect = 0.12 Identities = 19/89 (21%), Positives = 40/89 (44%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCEH 483 +V + ++ G + +L H + + S ++A+GS D+ + IW+ A+ + Sbjct: 428 TVRLWDVDRGICIHTLTKHQEPVYSVAFSPDGRYLASGSFDKCVHIWNTQTGALVHSYRG 487 Query: 482 DEGVTCLAWLGSSRYVASGCIDGMVRIWD 396 G+ + W + V + DG V + D Sbjct: 488 TGGIFEVCWNAAGDKVGASASDGSVCVLD 516
>TB1RB_XENLA (Q6GPC6) F-box-like/WD-repeat-containing protein TBL1XR1-B| (Transducin beta-like 1X-related homolog 1-B) (Nuclear receptor corepressor/HDAC3 complex subunit TBLR1-B) (TBL1-related protein 1-B) Length = 522 Score = 60.5 bits (145), Expect = 4e-09 Identities = 36/140 (25%), Positives = 63/140 (45%), Gaps = 10/140 (7%) Frame = -2 Query: 659 VHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQA-IRSTCEH 483 +H+ + + + + GHTN + I N +A+ S D TL IW + + H Sbjct: 339 IHVCKLGQDRPIKTFQGHTNEVNAIKWDPTGNLLASCSDDMTLKIWSMKHDTCVHDLQAH 398 Query: 482 DEGVTCLAWL---------GSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAV 330 ++ + + W ++ +AS D VR+WD G T + H++ V S+A Sbjct: 399 NKEIYTIKWSPTGPGTNNPNANLMLASASFDSTVRLWDVDRGICIHTLTKHQEPVYSVAF 458 Query: 329 SADGNSIVSVSTDKSARVFD 270 S DG + S S DK +++ Sbjct: 459 SPDGRYLASGSFDKCVHIWN 478 Score = 53.5 bits (127), Expect = 5e-07 Identities = 38/131 (29%), Positives = 60/131 (45%), Gaps = 15/131 (11%) Frame = -2 Query: 617 LVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLAR-------QAIRSTCEHDEG----- 474 L GH + + + + +A+GS D T IW+L+ Q + C + G Sbjct: 173 LRGHESEVFICAWNPVSDLLASGSGDSTARIWNLSENSTSGSTQLVLRHCIREGGQDVPS 232 Query: 473 ---VTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVS 303 VT L W +A+G DG RIW + G+LA T H+ + +L + GN I+S Sbjct: 233 NKDVTSLDWNSEGTLLATGSYDGFARIW-TKDGNLASTLGQHKGPIFALKWNKKGNFILS 291 Query: 302 VSTDKSARVFD 270 DK+ ++D Sbjct: 292 AGVDKTTIIWD 302 Score = 52.4 bits (124), Expect = 1e-06 Identities = 30/99 (30%), Positives = 55/99 (55%), Gaps = 1/99 (1%) Frame = -2 Query: 560 VATGSIDRTLIIWDLARQ-AIRSTCEHDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSG 384 +A+ S D T+ +WD+ R I + +H E V +A+ RY+ASG D V IW++ +G Sbjct: 423 LASASFDSTVRLWDVDRGICIHTLTKHQEPVYSVAFSPDGRYLASGSFDKCVHIWNTQTG 482 Query: 383 DLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFDI 267 L ++ G + + + +A G+ + + ++D S V D+ Sbjct: 483 ALVHSYRGTGGIFE-VCWNAAGDKVGASASDGSVCVLDL 520 Score = 40.8 bits (94), Expect = 0.004 Identities = 27/124 (21%), Positives = 55/124 (44%), Gaps = 1/124 (0%) Frame = -2 Query: 635 GQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDL-ARQAIRSTCEHDEGVTCLA 459 G + +L H I + + + N++ + +D+T IIWD +A + H + Sbjct: 264 GNLASTLGQHKGPIFALKWNKKGNFILSAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVD 323 Query: 458 WLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSAR 279 W ++ + AS D + + +TF GH + V ++ GN + S S D + + Sbjct: 324 WQSNNTF-ASCSTDMCIHVCKLGQDRPIKTFQGHTNEVNAIKWDPTGNLLASCSDDMTLK 382 Query: 278 VFDI 267 ++ + Sbjct: 383 IWSM 386 Score = 38.1 bits (87), Expect = 0.024 Identities = 29/119 (24%), Positives = 46/119 (38%), Gaps = 3/119 (2%) Frame = -2 Query: 623 GSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCEHDEGVTCLAWLGSS 444 G V + + +S +ATGS D IW + +H + L W Sbjct: 227 GQDVPSNKDVTSLDWNSEGTLLATGSYDGFARIWTKDGNLASTLGQHKGPIFALKWNKKG 286 Query: 443 RYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSAD---GNSIVSVSTDKSARV 276 ++ S +D IWD+ +G+ + F H + A+ D N+ S STD V Sbjct: 287 NFILSAGVDKTTIIWDAHTGEAKQQFPFH----SAPALDVDWQSNNTFASCSTDMCIHV 341 Score = 35.8 bits (81), Expect = 0.12 Identities = 19/89 (21%), Positives = 40/89 (44%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCEH 483 +V + ++ G + +L H + + S ++A+GS D+ + IW+ A+ + Sbjct: 431 TVRLWDVDRGICIHTLTKHQEPVYSVAFSPDGRYLASGSFDKCVHIWNTQTGALVHSYRG 490 Query: 482 DEGVTCLAWLGSSRYVASGCIDGMVRIWD 396 G+ + W + V + DG V + D Sbjct: 491 TGGIFEVCWNAAGDKVGASASDGSVCVLD 519
>TBL1Y_HUMAN (Q9BQ87) F-box-like/WD-repeat protein TBL1Y (Transducin beta-like| 1Y protein) (Transducin-beta-like 1, Y-linked) Length = 522 Score = 60.1 bits (144), Expect = 6e-09 Identities = 39/140 (27%), Positives = 61/140 (43%), Gaps = 10/140 (7%) Frame = -2 Query: 659 VHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQA-IRSTCEH 483 +H+ + V + GHTN + I +A+ S D TL IW + + A + H Sbjct: 341 IHVCRLGCDHPVKTFQGHTNEVNAIKWDPSGMLLASCSDDMTLKIWSMKQDACVHDLQAH 400 Query: 482 DEGVTCLAWL---------GSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAV 330 + + + W SS +AS D VR+WD G T H++ V S+A Sbjct: 401 SKEIYTIKWSPTGPATSNPNSSIMLASASFDSTVRLWDVEQGVCTHTLMKHQEPVYSVAF 460 Query: 329 SADGNSIVSVSTDKSARVFD 270 S DG + S S DK +++ Sbjct: 461 SPDGKYLASGSFDKYVHIWN 480 Score = 52.4 bits (124), Expect = 1e-06 Identities = 37/131 (28%), Positives = 59/131 (45%), Gaps = 15/131 (11%) Frame = -2 Query: 617 LVGHTNSIECIGISSRYNWVATGSIDRTLIIWDL-------ARQAIRSTCEHDEG----- 474 L GH + + + + +A+GS D T IW+L + Q + C + G Sbjct: 175 LRGHESEVFICAWNPVSDLLASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDVPS 234 Query: 473 ---VTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVS 303 VT L W +A G DG RIW +G+LA T H+ + +L + GN ++S Sbjct: 235 NKDVTSLDWNSDGTLLAMGSYDGFARIWTE-NGNLASTLGQHKGPIFALKWNKKGNYVLS 293 Query: 302 VSTDKSARVFD 270 DK+ ++D Sbjct: 294 AGVDKTTIIWD 304 Score = 51.6 bits (122), Expect = 2e-06 Identities = 29/99 (29%), Positives = 54/99 (54%), Gaps = 1/99 (1%) Frame = -2 Query: 560 VATGSIDRTLIIWDLARQAIRSTC-EHDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSG 384 +A+ S D T+ +WD+ + T +H E V +A+ +Y+ASG D V IW++ SG Sbjct: 425 LASASFDSTVRLWDVEQGVCTHTLMKHQEPVYSVAFSPDGKYLASGSFDKYVHIWNTQSG 484 Query: 383 DLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFDI 267 L ++ G + + + +A G+ + + ++D S V D+ Sbjct: 485 SLVHSYQGTGGIFE-VCWNARGDKVGASASDGSVCVLDL 522 Score = 38.5 bits (88), Expect = 0.018 Identities = 27/125 (21%), Positives = 54/125 (43%), Gaps = 1/125 (0%) Frame = -2 Query: 638 SGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDL-ARQAIRSTCEHDEGVTCL 462 +G + +L H I + + + N+V + +D+T IIWD +A + H + Sbjct: 265 NGNLASTLGQHKGPIFALKWNKKGNYVLSAGVDKTTIIWDAHTGEAKQQFPFHSAPALDV 324 Query: 461 AWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSA 282 W + + AS D + + +TF GH + V ++ G + S S D + Sbjct: 325 DWQNNMTF-ASCSTDMCIHVCRLGCDHPVKTFQGHTNEVNAIKWDPSGMLLASCSDDMTL 383 Query: 281 RVFDI 267 +++ + Sbjct: 384 KIWSM 388 Score = 35.4 bits (80), Expect = 0.15 Identities = 27/96 (28%), Positives = 38/96 (39%), Gaps = 1/96 (1%) Frame = -2 Query: 560 VATGSIDRTLIIWDLARQAIRSTCEHDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGD 381 +A GS D IW + +H + L W YV S +D IWD+ +G+ Sbjct: 250 LAMGSYDGFARIWTENGNLASTLGQHKGPIFALKWNKKGNYVLSAGVDKTTIIWDAHTGE 309 Query: 380 LARTFSGHRDVVQSLAVSADGN-SIVSVSTDKSARV 276 + F H +L V N + S STD V Sbjct: 310 AKQQFPFHS--APALDVDWQNNMTFASCSTDMCIHV 343 Score = 33.9 bits (76), Expect = 0.45 Identities = 18/89 (20%), Positives = 39/89 (43%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCEH 483 +V + + G +L+ H + + S ++A+GS D+ + IW+ ++ + + Sbjct: 433 TVRLWDVEQGVCTHTLMKHQEPVYSVAFSPDGKYLASGSFDKYVHIWNTQSGSLVHSYQG 492 Query: 482 DEGVTCLAWLGSSRYVASGCIDGMVRIWD 396 G+ + W V + DG V + D Sbjct: 493 TGGIFEVCWNARGDKVGASASDGSVCVLD 521
>PRP46_SCHPO (O13615) Pre-mRNA-splicing factor prp46 (Pre-mRNA-processing| protein 5) (Complexed with cdc5 protein 1) Length = 473 Score = 60.1 bits (144), Expect = 6e-09 Identities = 37/116 (31%), Positives = 56/116 (48%), Gaps = 1/116 (0%) Frame = -2 Query: 611 GHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCE-HDEGVTCLAWLGSSRYV 435 GH + C+ + W TG+ DRT+ IWDLA ++ T H V LA Y+ Sbjct: 161 GHLGWVRCVDVEPGNQWFCTGAGDRTIKIWDLASGVLKLTLTGHIATVRGLAVSPRHPYL 220 Query: 434 ASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFDI 267 S D MV+ WD + + R + GH V +L + + +V+ D ARV+D+ Sbjct: 221 FSCGEDKMVKCWDLETNKVIRHYHGHLSGVYALKLHPTLDVLVTAGRDAVARVWDM 276 Score = 57.0 bits (136), Expect = 5e-08 Identities = 36/137 (26%), Positives = 66/137 (48%), Gaps = 1/137 (0%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDL-ARQAIRSTCE 486 ++ I + SG + +L GH ++ + +S R+ ++ + D+ + WDL + IR Sbjct: 186 TIKIWDLASGVLKLTLTGHIATVRGLAVSPRHPYLFSCGEDKMVKCWDLETNKVIRHYHG 245 Query: 485 HDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIV 306 H GV L + + + D + R+WD + SGH+ V SLAV +V Sbjct: 246 HLSGVYALKLHPTLDVLVTAGRDAVARVWDMRTRQNVHVLSGHKSTVASLAVQEFDPQVV 305 Query: 305 SVSTDKSARVFDISMFK 255 + S D + R++D++ K Sbjct: 306 TGSMDSTIRLWDLAAGK 322 Score = 48.9 bits (115), Expect = 1e-05 Identities = 30/105 (28%), Positives = 51/105 (48%), Gaps = 1/105 (0%) Frame = -2 Query: 632 QVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLAR-QAIRSTCEHDEGVTCLAW 456 Q V L GH +++ + + V TGS+D T+ +WDLA + + + H + V L+ Sbjct: 280 QNVHVLSGHKSTVASLAVQEFDPQVVTGSMDSTIRLWDLAAGKTLTTLTHHKKTVRALSL 339 Query: 455 LGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSAD 321 ASG D ++ W G F GH +V +L++++D Sbjct: 340 HPDEFTFASGSSDN-IKHWKFPEGAFMGNFEGHNAIVNTLSINSD 383 Score = 42.0 bits (97), Expect = 0.002 Identities = 26/90 (28%), Positives = 40/90 (44%) Frame = -2 Query: 524 WDLARQAIRSTCEHDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVV 345 W +R H V C+ +++ +G D ++IWD SG L T +GH V Sbjct: 149 WHAPWTLMRVISGHLGWVRCVDVEPGNQWFCTGAGDRTIKIWDLASGVLKLTLTGHIATV 208 Query: 344 QSLAVSADGNSIVSVSTDKSARVFDISMFK 255 + LAVS + S DK + +D+ K Sbjct: 209 RGLAVSPRHPYLFSCGEDKMVKCWDLETNK 238
>GBLP_MEDSA (O24076) Guanine nucleotide-binding protein beta subunit-like| protein Length = 325 Score = 60.1 bits (144), Expect = 6e-09 Identities = 36/125 (28%), Positives = 61/125 (48%), Gaps = 7/125 (5%) Frame = -2 Query: 623 GSLVGHTNSIECIGIS-SRYNWVATGSIDRTLIIWDLARQ------AIRSTCEHDEGVTC 465 G++ HT+ + I + + T S D+++I+W L ++ R H V Sbjct: 9 GTMRAHTDVVTAIATPIDNSDMIVTASRDKSIILWHLTKEDKTYGVPRRRLTGHSHFVQD 68 Query: 464 LAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKS 285 + ++ SG DG +R+WD +G AR F GH V S+A S D IVS S D++ Sbjct: 69 VVLSSDGQFALSGSWDGELRLWDLNAGTSARRFVGHTKDVLSVAFSIDNRQIVSASRDRT 128 Query: 284 ARVFD 270 ++++ Sbjct: 129 IKLWN 133 Score = 56.6 bits (135), Expect = 6e-08 Identities = 34/132 (25%), Positives = 63/132 (47%), Gaps = 5/132 (3%) Frame = -2 Query: 644 INSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDL---ARQAIRSTCEHDEG 474 +N+G VGHT + + S + + S DRT+ +W+ + I+ H + Sbjct: 92 LNAGTSARRFVGHTKDVLSVAFSIDNRQIVSASRDRTIKLWNTLGECKYTIQDGDAHSDW 151 Query: 473 VTCLAWLGSSRY--VASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSV 300 V+C+ + S+ + S D V++W+ + L T +GH V ++AVS DG+ S Sbjct: 152 VSCVRFSPSTPQPTIVSASWDRTVKVWNLTNCKLRNTLAGHSGYVNTVAVSPDGSLCASG 211 Query: 299 STDKSARVFDIS 264 D ++D++ Sbjct: 212 GKDGVILLWDLA 223 Score = 42.0 bits (97), Expect = 0.002 Identities = 34/153 (22%), Positives = 65/153 (42%), Gaps = 18/153 (11%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCEH 483 +V + ++ + ++ +L GH+ + + +S + A+G D +++WDLA + + Sbjct: 174 TVKVWNLTNCKLRNTLAGHSGYVNTVAVSPDGSLCASGGKDGVILLWDLAEGKRLYSLDA 233 Query: 482 DEGVTCLAWLGSSRYVASGCIDGMVRIWD----SLSGDLARTFSGHRDVV---------- 345 + L + +RY + ++IWD S+ DL D Sbjct: 234 GSIIHALCF-SPNRYWLCAATESSIKIWDLESKSIVEDLKVDLKTEADAAIGGDTTTKKK 292 Query: 344 ----QSLAVSADGNSIVSVSTDKSARVFDISMF 258 SL SADG+++ S TD RV+ I + Sbjct: 293 VIYCTSLNWSADGSTLFSGYTDGVVRVWGIGRY 325 Score = 33.9 bits (76), Expect = 0.45 Identities = 22/80 (27%), Positives = 39/80 (48%), Gaps = 6/80 (7%) Frame = -2 Query: 485 HDEGVTCLAW-LGSSRYVASGCIDGMVRIW-----DSLSGDLARTFSGHRDVVQSLAVSA 324 H + VT +A + +S + + D + +W D G R +GH VQ + +S+ Sbjct: 14 HTDVVTAIATPIDNSDMIVTASRDKSIILWHLTKEDKTYGVPRRRLTGHSHFVQDVVLSS 73 Query: 323 DGNSIVSVSTDKSARVFDIS 264 DG +S S D R++D++ Sbjct: 74 DGQFALSGSWDGELRLWDLN 93
>COPB2_RAT (O35142) Coatomer subunit beta' (Beta'-coat protein) (Beta'-COP)| (p102) Length = 904 Score = 60.1 bits (144), Expect = 6e-09 Identities = 38/127 (29%), Positives = 65/127 (51%), Gaps = 4/127 (3%) Frame = -2 Query: 611 GHTNSIECIGISSR-YNWVATGSIDRTLIIWDLARQAIRSTCE-HDEGVTCLAWL--GSS 444 GHT+ + I I+ + N A+ S+DRT+ +W L + T E H++GV C+ + G Sbjct: 139 GHTHYVMQIVINPKDNNQFASASLDRTIKVWQLGSSSPNFTLEGHEKGVNCIDYYSGGDK 198 Query: 443 RYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFDIS 264 Y+ SG D +V+IWD + +T GH V + I++ S D + R++ S Sbjct: 199 PYLISGADDRLVKIWDYQNKTCVQTPEGHAQNVSCATFHPELPIIITGSEDGTVRIWHSS 258 Query: 263 MFK*EKS 243 ++ E + Sbjct: 259 TYRLEST 265 Score = 44.7 bits (104), Expect = 3e-04 Identities = 34/130 (26%), Positives = 62/130 (47%), Gaps = 3/130 (2%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYN--WVATGSIDRTLIIWDLARQAIRSTC 489 ++ + + S +L GH + CI S + ++ +G+ DR + IWD + T Sbjct: 165 TIKVWQLGSSSPNFTLEGHEKGVNCIDYYSGGDKPYLISGADDRLVKIWDYQNKTCVQTP 224 Query: 488 E-HDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNS 312 E H + V+C + + +G DG VRIW S + L T + + V +A S G++ Sbjct: 225 EGHAQNVSCATFHPELPIIITGSEDGTVRIWHSSTYRLESTLNYGMERVWCVA-SLRGSN 283 Query: 311 IVSVSTDKSA 282 V++ D+ + Sbjct: 284 NVALGYDEGS 293 Score = 44.7 bits (104), Expect = 3e-04 Identities = 23/106 (21%), Positives = 52/106 (49%), Gaps = 3/106 (2%) Frame = -2 Query: 575 SRYNWVATGSIDRTLIIWDL-ARQAIRSTCEHDEGVTCLAWLGSSRYVASGCIDGMVRIW 399 +R NWV TG+ D + +++ + + H + + C+A + ++ + D ++++W Sbjct: 66 ARKNWVVTGADDMQIRVFNYNTLERVHMFEAHSDYIRCIAVHPTQPFILTSSDDMLIKLW 125 Query: 398 D-SLSGDLARTFSGHRDVVQSLAVS-ADGNSIVSVSTDKSARVFDI 267 D ++ F GH V + ++ D N S S D++ +V+ + Sbjct: 126 DWDKKWSCSQVFEGHTHYVMQIVINPKDNNQFASASLDRTIKVWQL 171
>TBL1X_HUMAN (O60907) F-box-like/WD-repeat protein TBL1X (Transducin beta-like| 1X protein) (Transducin-beta-like 1, X-linked) (SMAP55) Length = 526 Score = 60.1 bits (144), Expect = 6e-09 Identities = 38/140 (27%), Positives = 64/140 (45%), Gaps = 10/140 (7%) Frame = -2 Query: 659 VHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQA-IRSTCEH 483 +H+ + + V + GHTN + I +A+ S D TL IW + ++ I H Sbjct: 343 IHVCRLGCDRPVKTFQGHTNEVNAIKWDPSGMLLASCSDDMTLKIWSMKQEVCIHDLQAH 402 Query: 482 DEGVTCLAWL---------GSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAV 330 ++ + + W S+ +AS D VR+WD G T + H++ V S+A Sbjct: 403 NKEIYTIKWSPTGPATSNPNSNIMLASASFDSTVRLWDIERGVCTHTLTKHQEPVYSVAF 462 Query: 329 SADGNSIVSVSTDKSARVFD 270 S DG + S S DK +++ Sbjct: 463 SPDGKYLASGSFDKCVHIWN 482 Score = 53.5 bits (127), Expect = 5e-07 Identities = 30/99 (30%), Positives = 55/99 (55%), Gaps = 1/99 (1%) Frame = -2 Query: 560 VATGSIDRTLIIWDLARQAIRSTC-EHDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSG 384 +A+ S D T+ +WD+ R T +H E V +A+ +Y+ASG D V IW++ SG Sbjct: 427 LASASFDSTVRLWDIERGVCTHTLTKHQEPVYSVAFSPDGKYLASGSFDKCVHIWNTQSG 486 Query: 383 DLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFDI 267 +L ++ G + + + +A G+ + + ++D S V D+ Sbjct: 487 NLVHSYRGTGGIFE-VCWNARGDKVGASASDGSVCVLDL 524 Score = 52.8 bits (125), Expect = 9e-07 Identities = 38/131 (29%), Positives = 60/131 (45%), Gaps = 15/131 (11%) Frame = -2 Query: 617 LVGHTNSIECIGISSRYNWVATGSIDRTLIIWDL-------ARQAIRSTCEHDEG----- 474 L GH + + + + +A+GS D T IW+L + Q + C + G Sbjct: 177 LRGHESEVFICAWNPVSDLLASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDVPS 236 Query: 473 ---VTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVS 303 VT L W + +A+G DG RIW G+LA T H+ + +L + GN I+S Sbjct: 237 NKDVTSLDWNTNGTLLATGSYDGFARIWTE-DGNLASTLGQHKGPIFALKWNRKGNYILS 295 Query: 302 VSTDKSARVFD 270 DK+ ++D Sbjct: 296 AGVDKTTIIWD 306 Score = 37.7 bits (86), Expect = 0.031 Identities = 26/124 (20%), Positives = 54/124 (43%), Gaps = 1/124 (0%) Frame = -2 Query: 635 GQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDL-ARQAIRSTCEHDEGVTCLA 459 G + +L H I + + + N++ + +D+T IIWD +A + H + Sbjct: 268 GNLASTLGQHKGPIFALKWNRKGNYILSAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVD 327 Query: 458 WLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSAR 279 W ++ + AS D + + +TF GH + V ++ G + S S D + + Sbjct: 328 WQNNTTF-ASCSTDMCIHVCRLGCDRPVKTFQGHTNEVNAIKWDPSGMLLASCSDDMTLK 386 Query: 278 VFDI 267 ++ + Sbjct: 387 IWSM 390 Score = 37.4 bits (85), Expect = 0.040 Identities = 27/96 (28%), Positives = 39/96 (40%), Gaps = 1/96 (1%) Frame = -2 Query: 560 VATGSIDRTLIIWDLARQAIRSTCEHDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGD 381 +ATGS D IW + +H + L W Y+ S +D IWD+ +G+ Sbjct: 252 LATGSYDGFARIWTEDGNLASTLGQHKGPIFALKWNRKGNYILSAGVDKTTIIWDAHTGE 311 Query: 380 LARTFSGHRDVVQSLAVSADGN-SIVSVSTDKSARV 276 + F H +L V N + S STD V Sbjct: 312 AKQQFPFHS--APALDVDWQNNTTFASCSTDMCIHV 345 Score = 32.0 bits (71), Expect = 1.7 Identities = 19/89 (21%), Positives = 36/89 (40%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCEH 483 +V + I G +L H + + S ++A+GS D+ + IW+ + + Sbjct: 435 TVRLWDIERGVCTHTLTKHQEPVYSVAFSPDGKYLASGSFDKCVHIWNTQSGNLVHSYRG 494 Query: 482 DEGVTCLAWLGSSRYVASGCIDGMVRIWD 396 G+ + W V + DG V + D Sbjct: 495 TGGIFEVCWNARGDKVGASASDGSVCVLD 523
>GBB1_CAEEL (P17343) Guanine nucleotide-binding protein beta subunit 1| Length = 340 Score = 59.7 bits (143), Expect = 8e-09 Identities = 40/135 (29%), Positives = 59/135 (43%), Gaps = 3/135 (2%) Frame = -2 Query: 662 SVHIVSINSGQVVGS--LVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLAR-QAIRST 492 S++ + G V S L GHT + C N + T S D T +WD+ Q + Sbjct: 122 SIYSLKTREGNVRVSRELPGHTGYLSCCRFLDD-NQIVTSSGDMTCALWDIETGQQCTAF 180 Query: 491 CEHDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNS 312 H V L+ R SG D ++WD G +TF GH + ++A GN+ Sbjct: 181 TGHTGDVMSLSLSPDFRTFISGACDASAKLWDIRDGMCKQTFPGHESDINAVAFFPSGNA 240 Query: 311 IVSVSTDKSARVFDI 267 + S D + R+FDI Sbjct: 241 FATGSDDATCRLFDI 255 Score = 58.2 bits (139), Expect = 2e-08 Identities = 36/134 (26%), Positives = 62/134 (46%), Gaps = 3/134 (2%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCEH 483 S + I G + GH + I + N ATGS D T ++D+ + H Sbjct: 207 SAKLWDIRDGMCKQTFPGHESDINAVAFFPSGNAFATGSDDATCRLFDIRADQELAMYSH 266 Query: 482 DE---GVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNS 312 D G+T +A+ S R + +G D +WDS+ + A +GH + V L V+ DG + Sbjct: 267 DNIICGITSVAFSKSGRLLFAGYDDFNCNVWDSMRQERAGVLAGHDNRVSCLGVTEDGMA 326 Query: 311 IVSVSTDKSARVFD 270 + + S D ++++ Sbjct: 327 VCTGSWDSFLKIWN 340 Score = 36.6 bits (83), Expect = 0.069 Identities = 38/164 (23%), Positives = 60/164 (36%), Gaps = 46/164 (28%) Frame = -2 Query: 620 SLVGHTNSIECIGISSRYNWVATGSIDRTLIIWD-LARQAIRSTCEHDEGVTCLAWLGSS 444 +L GH I + +S + + S D LI+WD + + V A+ S Sbjct: 50 TLRGHLAKIYAMHWASDSRNLVSASQDGKLIVWDSYTTNKVHAIPLRSSWVMTCAYAPSG 109 Query: 443 RYVASGCID------------GMVRI---------------------------------W 399 +VA G +D G VR+ W Sbjct: 110 SFVACGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFLDDNQIVTSSGDMTCALW 169 Query: 398 DSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFDI 267 D +G F+GH V SL++S D + +S + D SA+++DI Sbjct: 170 DIETGQQCTAFTGHTGDVMSLSLSPDFRTFISGACDASAKLWDI 213
>GBB1_CAEBR (Q61ZF6) Guanine nucleotide-binding protein beta subunit 1| Length = 340 Score = 59.7 bits (143), Expect = 8e-09 Identities = 40/135 (29%), Positives = 59/135 (43%), Gaps = 3/135 (2%) Frame = -2 Query: 662 SVHIVSINSGQVVGS--LVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLAR-QAIRST 492 S++ + G V S L GHT + C N + T S D T +WD+ Q + Sbjct: 122 SIYSLKTREGNVRVSRELPGHTGYLSCCRFLDD-NQIVTSSGDMTCALWDIETGQQCTAF 180 Query: 491 CEHDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNS 312 H V L+ R SG D ++WD G +TF GH + ++A GN+ Sbjct: 181 TGHTGDVMSLSLSPDFRTFISGACDASAKLWDIRDGMCKQTFPGHESDINAVAFFPSGNA 240 Query: 311 IVSVSTDKSARVFDI 267 + S D + R+FDI Sbjct: 241 FATGSDDATCRLFDI 255 Score = 58.2 bits (139), Expect = 2e-08 Identities = 36/134 (26%), Positives = 62/134 (46%), Gaps = 3/134 (2%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCEH 483 S + I G + GH + I + N ATGS D T ++D+ + H Sbjct: 207 SAKLWDIRDGMCKQTFPGHESDINAVAFFPSGNAFATGSDDATCRLFDIRADQELAMYSH 266 Query: 482 DE---GVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNS 312 D G+T +A+ S R + +G D +WDS+ + A +GH + V L V+ DG + Sbjct: 267 DNIICGITSVAFSKSGRLLFAGYDDFNCNVWDSMRQERAGVLAGHDNRVSCLGVTEDGMA 326 Query: 311 IVSVSTDKSARVFD 270 + + S D ++++ Sbjct: 327 VCTGSWDSFLKIWN 340 Score = 36.6 bits (83), Expect = 0.069 Identities = 38/164 (23%), Positives = 60/164 (36%), Gaps = 46/164 (28%) Frame = -2 Query: 620 SLVGHTNSIECIGISSRYNWVATGSIDRTLIIWD-LARQAIRSTCEHDEGVTCLAWLGSS 444 +L GH I + +S + + S D LI+WD + + V A+ S Sbjct: 50 TLRGHLAKIYAMHWASDSRNLVSASQDGKLIVWDSYTTNKVHAIPLRSSWVMTCAYAPSG 109 Query: 443 RYVASGCID------------GMVRI---------------------------------W 399 +VA G +D G VR+ W Sbjct: 110 SFVACGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFLDDNQIVTSSGDMTCALW 169 Query: 398 DSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFDI 267 D +G F+GH V SL++S D + +S + D SA+++DI Sbjct: 170 DIETGQQCTAFTGHTGDVMSLSLSPDFRTFISGACDASAKLWDI 213
>FBXW7_MOUSE (Q8VBV4) F-box/WD-repeat protein 7 (F-box and WD-40 domain protein| 7) (F-box protein FBW7) (F-box protein Fbxw6) (F-box-WD40 repeat protein 6) (SEL-10) Length = 629 Score = 59.7 bits (143), Expect = 8e-09 Identities = 35/133 (26%), Positives = 68/133 (51%), Gaps = 1/133 (0%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCE- 486 ++ + I +GQ + L+GH ++ C+ R V +G+ D + +WD + T + Sbjct: 404 TLRVWDIETGQCLHVLMGHVAAVRCVQYDGRR--VVSGAYDFMVKVWDPETETCLHTLQG 461 Query: 485 HDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIV 306 H V L + G +V SG +D +R+WD +G+ T +GH+ + + + N +V Sbjct: 462 HTNRVYSLQFDGI--HVVSGSLDTSIRVWDVETGNCIHTLTGHQSLTSGMELK--DNILV 517 Query: 305 SVSTDKSARVFDI 267 S + D + +++DI Sbjct: 518 SGNADSTVKIWDI 530 Score = 55.5 bits (132), Expect = 1e-07 Identities = 39/132 (29%), Positives = 63/132 (47%), Gaps = 1/132 (0%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLAR-QAIRSTCE 486 ++ + S +G+ + +LVGHT + R N + +GS DRTL +W+ + I + Sbjct: 324 TLKVWSAVTGKCLRTLVGHTGGVW--SSQMRDNIIISGSTDRTLKVWNAETGECIHTLYG 381 Query: 485 HDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIV 306 H V C+ + V SG D +R+WD +G GH V+ V DG +V Sbjct: 382 HTSTVRCMHL--HEKRVVSGSRDATLRVWDIETGQCLHVLMGHVAAVR--CVQYDGRRVV 437 Query: 305 SVSTDKSARVFD 270 S + D +V+D Sbjct: 438 SGAYDFMVKVWD 449 Score = 46.6 bits (109), Expect = 7e-05 Identities = 35/121 (28%), Positives = 58/121 (47%), Gaps = 4/121 (3%) Frame = -2 Query: 617 LVGHTNS-IECIGISSRYNWVATGSIDRTLIIWD-LARQAIRSTCEHDEGVTCLAWLGSS 444 L GH + I C+ N + +GS D TL +W + + +R+ H GV W Sbjct: 298 LKGHDDHVITCLQFCG--NRIVSGSDDNTLKVWSAVTGKCLRTLVGHTGGV----WSSQM 351 Query: 443 R--YVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFD 270 R + SG D +++W++ +G+ T GH V+ + + +VS S D + RV+D Sbjct: 352 RDNIIISGSTDRTLKVWNAETGECIHTLYGHTSTVRCMHLHE--KRVVSGSRDATLRVWD 409 Query: 269 I 267 I Sbjct: 410 I 410
>TBLX_MOUSE (Q9QXE7) F-box-like/WD-repeat protein TBL1X (Transducin beta-like| 1X protein) Length = 527 Score = 59.7 bits (143), Expect = 8e-09 Identities = 38/140 (27%), Positives = 63/140 (45%), Gaps = 10/140 (7%) Frame = -2 Query: 659 VHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQA-IRSTCEH 483 +H+ + + V + GHTN + I +A+ S D TL IW + + A + H Sbjct: 344 IHVCRLGCDRPVKTFQGHTNEVNAIKWDPSGMLLASCSDDMTLKIWSMKQDACVHDLQAH 403 Query: 482 DEGVTCLAWL---------GSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAV 330 + + + W S+ +AS D VR+WD G T + H++ V S+A Sbjct: 404 SKEIYTIKWSPTGPATSNPNSNIMLASASFDSTVRLWDVERGVCIHTLTKHQEPVYSVAF 463 Query: 329 SADGNSIVSVSTDKSARVFD 270 S DG + S S DK +++ Sbjct: 464 SPDGKYLASGSFDKCVHIWN 483 Score = 53.5 bits (127), Expect = 5e-07 Identities = 30/99 (30%), Positives = 55/99 (55%), Gaps = 1/99 (1%) Frame = -2 Query: 560 VATGSIDRTLIIWDLARQA-IRSTCEHDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSG 384 +A+ S D T+ +WD+ R I + +H E V +A+ +Y+ASG D V IW++ SG Sbjct: 428 LASASFDSTVRLWDVERGVCIHTLTKHQEPVYSVAFSPDGKYLASGSFDKCVHIWNTQSG 487 Query: 383 DLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFDI 267 L ++ G + + + +A G+ + + ++D S V D+ Sbjct: 488 SLVHSYRGTGGIFE-VCWNARGDKVGASASDGSVCVLDL 525 Score = 53.1 bits (126), Expect = 7e-07 Identities = 38/131 (29%), Positives = 59/131 (45%), Gaps = 15/131 (11%) Frame = -2 Query: 617 LVGHTNSIECIGISSRYNWVATGSIDRTLIIWDL-------ARQAIRSTCEHDEG----- 474 L GH + + + + +A+GS D T IW+L + Q + C + G Sbjct: 178 LRGHESEVFICAWNPVSDLLASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDVPS 237 Query: 473 ---VTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVS 303 VT L W +A+G DG RIW G+LA T H+ + +L + GN I+S Sbjct: 238 NKDVTSLDWNSDGTLLATGSYDGFARIWTE-DGNLASTLGQHKGPIFALKWNKKGNYILS 296 Query: 302 VSTDKSARVFD 270 DK+ ++D Sbjct: 297 AGVDKTTIIWD 307 Score = 38.1 bits (87), Expect = 0.024 Identities = 26/124 (20%), Positives = 54/124 (43%), Gaps = 1/124 (0%) Frame = -2 Query: 635 GQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDL-ARQAIRSTCEHDEGVTCLA 459 G + +L H I + + + N++ + +D+T IIWD +A + H + Sbjct: 269 GNLASTLGQHKGPIFALKWNKKGNYILSAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVD 328 Query: 458 WLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSAR 279 W ++ + AS D + + +TF GH + V ++ G + S S D + + Sbjct: 329 WQNNTTF-ASCSTDMCIHVCRLGCDRPVKTFQGHTNEVNAIKWDPSGMLLASCSDDMTLK 387 Query: 278 VFDI 267 ++ + Sbjct: 388 IWSM 391 Score = 37.4 bits (85), Expect = 0.040 Identities = 27/96 (28%), Positives = 39/96 (40%), Gaps = 1/96 (1%) Frame = -2 Query: 560 VATGSIDRTLIIWDLARQAIRSTCEHDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGD 381 +ATGS D IW + +H + L W Y+ S +D IWD+ +G+ Sbjct: 253 LATGSYDGFARIWTEDGNLASTLGQHKGPIFALKWNKKGNYILSAGVDKTTIIWDAHTGE 312 Query: 380 LARTFSGHRDVVQSLAVSADGN-SIVSVSTDKSARV 276 + F H +L V N + S STD V Sbjct: 313 AKQQFPFHS--APALDVDWQNNTTFASCSTDMCIHV 346 Score = 33.9 bits (76), Expect = 0.45 Identities = 18/89 (20%), Positives = 38/89 (42%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCEH 483 +V + + G + +L H + + S ++A+GS D+ + IW+ ++ + Sbjct: 436 TVRLWDVERGVCIHTLTKHQEPVYSVAFSPDGKYLASGSFDKCVHIWNTQSGSLVHSYRG 495 Query: 482 DEGVTCLAWLGSSRYVASGCIDGMVRIWD 396 G+ + W V + DG V + D Sbjct: 496 TGGIFEVCWNARGDKVGASASDGSVCVLD 524
>FBXW7_HUMAN (Q969H0) F-box/WD-repeat protein 7 (F-box and WD-40 domain protein| 7) (F-box protein FBX30) (hCdc4) (Archipelago homolog) (hAgo) (SEL-10) Length = 707 Score = 59.7 bits (143), Expect = 8e-09 Identities = 35/133 (26%), Positives = 68/133 (51%), Gaps = 1/133 (0%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCE- 486 ++ + I +GQ + L+GH ++ C+ R V +G+ D + +WD + T + Sbjct: 482 TLRVWDIETGQCLHVLMGHVAAVRCVQYDGRR--VVSGAYDFMVKVWDPETETCLHTLQG 539 Query: 485 HDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIV 306 H V L + G +V SG +D +R+WD +G+ T +GH+ + + + N +V Sbjct: 540 HTNRVYSLQFDGI--HVVSGSLDTSIRVWDVETGNCIHTLTGHQSLTSGMELK--DNILV 595 Query: 305 SVSTDKSARVFDI 267 S + D + +++DI Sbjct: 596 SGNADSTVKIWDI 608 Score = 55.5 bits (132), Expect = 1e-07 Identities = 39/132 (29%), Positives = 63/132 (47%), Gaps = 1/132 (0%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLAR-QAIRSTCE 486 ++ + S +G+ + +LVGHT + R N + +GS DRTL +W+ + I + Sbjct: 402 TLKVWSAVTGKCLRTLVGHTGGVW--SSQMRDNIIISGSTDRTLKVWNAETGECIHTLYG 459 Query: 485 HDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIV 306 H V C+ + V SG D +R+WD +G GH V+ V DG +V Sbjct: 460 HTSTVRCMHL--HEKRVVSGSRDATLRVWDIETGQCLHVLMGHVAAVR--CVQYDGRRVV 515 Query: 305 SVSTDKSARVFD 270 S + D +V+D Sbjct: 516 SGAYDFMVKVWD 527 Score = 46.6 bits (109), Expect = 7e-05 Identities = 35/121 (28%), Positives = 58/121 (47%), Gaps = 4/121 (3%) Frame = -2 Query: 617 LVGHTNS-IECIGISSRYNWVATGSIDRTLIIWD-LARQAIRSTCEHDEGVTCLAWLGSS 444 L GH + I C+ N + +GS D TL +W + + +R+ H GV W Sbjct: 376 LKGHDDHVITCLQFCG--NRIVSGSDDNTLKVWSAVTGKCLRTLVGHTGGV----WSSQM 429 Query: 443 R--YVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFD 270 R + SG D +++W++ +G+ T GH V+ + + +VS S D + RV+D Sbjct: 430 RDNIIISGSTDRTLKVWNAETGECIHTLYGHTSTVRCMHLHE--KRVVSGSRDATLRVWD 487 Query: 269 I 267 I Sbjct: 488 I 488
>GBLP_SCHPO (Q10281) Guanine nucleotide-binding protein beta subunit-like| protein (Receptor of activated protein kinase C) Length = 314 Score = 59.3 bits (142), Expect = 1e-08 Identities = 35/125 (28%), Positives = 62/125 (49%), Gaps = 7/125 (5%) Frame = -2 Query: 620 SLVGHTNSIECIGISSRY-NWVATGSIDRTLIIWDLARQAI------RSTCEHDEGVTCL 462 +L GH+ + + + + + +GS D+++I+W+L R + R H V+ Sbjct: 10 TLEGHSGWVTSLSTAPENPDILLSGSRDKSIILWNLVRDDVNYGVAQRRLTGHSHFVSDC 69 Query: 461 AWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSA 282 A S Y S D +R+WD G+ F GH V S+++S D +VS S DK+ Sbjct: 70 ALSFDSHYALSASWDKTIRLWDLEKGECTHQFVGHTSDVLSVSISPDNRQVVSGSRDKTI 129 Query: 281 RVFDI 267 ++++I Sbjct: 130 KIWNI 134 Score = 55.8 bits (133), Expect = 1e-07 Identities = 33/138 (23%), Positives = 69/138 (50%), Gaps = 5/138 (3%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCE- 486 ++ + + G+ VGHT+ + + IS V +GS D+T+ IW++ + + Sbjct: 86 TIRLWDLEKGECTHQFVGHTSDVLSVSISPDNRQVVSGSRDKTIKIWNIIGNCKYTITDG 145 Query: 485 -HDEGVTCLAWL---GSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADG 318 H + V+C+ + + +V++G D V++WD + L + GH V ++ +S DG Sbjct: 146 GHSDWVSCVRFSPNPDNLTFVSAGW-DKAVKVWDLETFSLRTSHYGHTGYVSAVTISPDG 204 Query: 317 NSIVSVSTDKSARVFDIS 264 + S D + ++D++ Sbjct: 205 SLCASGGRDGTLMLWDLN 222 Score = 52.4 bits (124), Expect = 1e-06 Identities = 35/133 (26%), Positives = 61/133 (45%), Gaps = 4/133 (3%) Frame = -2 Query: 644 INSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLAR-QAIRSTCEHDEGVT 468 +N G L GH++ + +S ++ + S D+T+ +WDL + + H V Sbjct: 50 VNYGVAQRRLTGHSHFVSDCALSFDSHYALSASWDKTIRLWDLEKGECTHQFVGHTSDVL 109 Query: 467 CLAWLGSSRYVASGCIDGMVRIWDSLSG-DLARTFSGHRDVVQSLAVS--ADGNSIVSVS 297 ++ +R V SG D ++IW+ + T GH D V + S D + VS Sbjct: 110 SVSISPDNRQVVSGSRDKTIKIWNIIGNCKYTITDGGHSDWVSCVRFSPNPDNLTFVSAG 169 Query: 296 TDKSARVFDISMF 258 DK+ +V+D+ F Sbjct: 170 WDKAVKVWDLETF 182
>FBXW7_DROME (Q9VZF4) F-box/WD-repeat protein 7 (F-box and WD-40 domain protein 7)| (Protein archipelago) Length = 1326 Score = 59.3 bits (142), Expect = 1e-08 Identities = 42/131 (32%), Positives = 64/131 (48%), Gaps = 1/131 (0%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCE- 486 ++ + S +G+ + +LVGHT + +S N + +GS DRTL +WD+ A T + Sbjct: 1016 TLKVWSAVNGKCLRTLVGHTGGVWSSQMSG--NIIISGSTDRTLKVWDMDSGACVHTLQG 1073 Query: 485 HDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIV 306 H V C+ GS V SG D +R+WD G GH V+ V DG IV Sbjct: 1074 HTSTVRCMHLHGSK--VVSGSRDATLRVWDIEQGSCLHVLVGHLAAVR--CVQYDGKLIV 1129 Query: 305 SVSTDKSARVF 273 S + D +++ Sbjct: 1130 SGAYDYMVKIW 1140 Score = 57.8 bits (138), Expect = 3e-08 Identities = 36/134 (26%), Positives = 66/134 (49%), Gaps = 1/134 (0%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCE- 486 ++ + I G + LVGH ++ C+ + + +G+ D + IW RQ T + Sbjct: 1096 TLRVWDIEQGSCLHVLVGHLAAVRCVQYDGKL--IVSGAYDYMVKIWHPERQECLHTLQG 1153 Query: 485 HDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIV 306 H V L + G +V SG +D +R+WD +G+ T GH+ + + + N +V Sbjct: 1154 HTNRVYSLQFDGL--HVVSGSLDTSIRVWDVETGNCKHTLMGHQSLTSGMELRQ--NILV 1209 Query: 305 SVSTDKSARVFDIS 264 S + D + +V+DI+ Sbjct: 1210 SGNADSTVKVWDIT 1223 Score = 55.5 bits (132), Expect = 1e-07 Identities = 30/101 (29%), Positives = 53/101 (52%), Gaps = 4/101 (3%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLAR----QAIRS 495 S+ + + +G +L+GH + G+ R N + +G+ D T+ +WD+ Q + Sbjct: 1176 SIRVWDVETGNCKHTLMGHQSLTS--GMELRQNILVSGNADSTVKVWDITTGQCLQTLSG 1233 Query: 494 TCEHDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLAR 372 +H VTCL + +SR+V + DG V++WD +GD R Sbjct: 1234 PNKHHSAVTCLQF--NSRFVVTSSDDGTVKLWDVKTGDFIR 1272 Score = 53.5 bits (127), Expect = 5e-07 Identities = 38/119 (31%), Positives = 58/119 (48%), Gaps = 2/119 (1%) Frame = -2 Query: 617 LVGHTNS-IECIGISSRYNWVATGSIDRTLIIWDLAR-QAIRSTCEHDEGVTCLAWLGSS 444 L GH + I C+ S N + +GS D TL +W + +R+ H GV G+ Sbjct: 990 LKGHDDHVITCLQFSG--NRIVSGSDDNTLKVWSAVNGKCLRTLVGHTGGVWSSQMSGN- 1046 Query: 443 RYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFDI 267 + SG D +++WD SG T GH V+ + + G+ +VS S D + RV+DI Sbjct: 1047 -IIISGSTDRTLKVWDMDSGACVHTLQGHTSTVRCMHL--HGSKVVSGSRDATLRVWDI 1102
>PRL1_ARATH (Q42384) PP1/PP2A phosphatases pleiotropic regulator PRL1| Length = 486 Score = 59.3 bits (142), Expect = 1e-08 Identities = 36/116 (31%), Positives = 53/116 (45%), Gaps = 1/116 (0%) Frame = -2 Query: 611 GHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCE-HDEGVTCLAWLGSSRYV 435 GH + + W TGS DRT+ IWD+A ++ T H E V LA Y+ Sbjct: 174 GHLGWVRSVAFDPSNEWFCTGSADRTIKIWDVATGVLKLTLTGHIEQVRGLAVSNRHTYM 233 Query: 434 ASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFDI 267 S D V+ WD + R++ GH V LA+ + +++ D RV+DI Sbjct: 234 FSAGDDKQVKCWDLEQNKVIRSYHGHLSGVYCLALHPTLDVLLTGGRDSVCRVWDI 289 Score = 55.5 bits (132), Expect = 1e-07 Identities = 34/133 (25%), Positives = 66/133 (49%), Gaps = 1/133 (0%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLAR-QAIRSTCE 486 ++ I + +G + +L GH + + +S+R+ ++ + D+ + WDL + + IRS Sbjct: 199 TIKIWDVATGVLKLTLTGHIEQVRGLAVSNRHTYMFSAGDDKQVKCWDLEQNKVIRSYHG 258 Query: 485 HDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIV 306 H GV CLA + + +G D + R+WD + SGH + V S+ +V Sbjct: 259 HLSGVYCLALHPTLDVLLTGGRDSVCRVWDIRTKMQIFALSGHDNTVCSVFTRPTDPQVV 318 Query: 305 SVSTDKSARVFDI 267 + S D + + +D+ Sbjct: 319 TGSHDTTIKFWDL 331 Score = 50.4 bits (119), Expect = 5e-06 Identities = 27/123 (21%), Positives = 54/123 (43%), Gaps = 1/123 (0%) Frame = -2 Query: 644 INSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDL-ARQAIRSTCEHDEGVT 468 + +V+ S GH + + C+ + + + TG D +WD+ + I + HD V Sbjct: 247 LEQNKVIRSYHGHLSGVYCLALHPTLDVLLTGGRDSVCRVWDIRTKMQIFALSGHDNTVC 306 Query: 467 CLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDK 288 + + V +G D ++ WD G T + H+ V+++ + N+ S S D Sbjct: 307 SVFTRPTDPQVVTGSHDTTIKFWDLRYGKTMSTLTHHKKSVRAMTLHPKENAFASASADN 366 Query: 287 SAR 279 + + Sbjct: 367 TKK 369 Score = 43.1 bits (100), Expect = 7e-04 Identities = 23/73 (31%), Positives = 38/73 (52%) Frame = -2 Query: 473 VTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVST 294 V +A+ S+ + +G D ++IWD +G L T +GH + V+ LAVS + S Sbjct: 179 VRSVAFDPSNEWFCTGSADRTIKIWDVATGVLKLTLTGHIEQVRGLAVSNRHTYMFSAGD 238 Query: 293 DKSARVFDISMFK 255 DK + +D+ K Sbjct: 239 DKQVKCWDLEQNK 251
>PRP46_CRYNE (Q5KDR4) Pre-mRNA-splicing factor PRP46 (Pre-mRNA-processing| protein 46) Length = 473 Score = 58.9 bits (141), Expect = 1e-08 Identities = 37/116 (31%), Positives = 56/116 (48%), Gaps = 1/116 (0%) Frame = -2 Query: 611 GHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIR-STCEHDEGVTCLAWLGSSRYV 435 GH + + + W ATG+ DR + IWDLA ++ S H + LA Y+ Sbjct: 180 GHMGWVRAVAMDPGNQWFATGAGDRVIKIWDLASGELKLSLTGHISTIRGLAVSDRHPYL 239 Query: 434 ASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFDI 267 S D MV+ WD + + R + GH V SL+V + +V+ D S RV+D+ Sbjct: 240 FSCAEDKMVKCWDLETNKVIRHYHGHFSGVYSLSVHPTLDVLVTGGRDASVRVWDM 295 Score = 58.2 bits (139), Expect = 2e-08 Identities = 37/136 (27%), Positives = 67/136 (49%), Gaps = 1/136 (0%) Frame = -2 Query: 659 VHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDL-ARQAIRSTCEH 483 + I + SG++ SL GH ++I + +S R+ ++ + + D+ + WDL + IR H Sbjct: 206 IKIWDLASGELKLSLTGHISTIRGLAVSDRHPYLFSCAEDKMVKCWDLETNKVIRHYHGH 265 Query: 482 DEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVS 303 GV L+ + + +G D VR+WD + T +GH V + I+S Sbjct: 266 FSGVYSLSVHPTLDVLVTGGRDASVRVWDMRTRANIFTLTGHTSTVGDVKTQDSDPQIIS 325 Query: 302 VSTDKSARVFDISMFK 255 S D + R++D++ K Sbjct: 326 GSMDSTVRLWDLAAGK 341 Score = 45.4 bits (106), Expect = 1e-04 Identities = 27/116 (23%), Positives = 56/116 (48%), Gaps = 2/116 (1%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLAR-QAIRSTCE 486 SV + + + + +L GHT+++ + + +GS+D T+ +WDLA + + + Sbjct: 289 SVRVWDMRTRANIFTLTGHTSTVGDVKTQDSDPQIISGSMDSTVRLWDLAAGKCMNTLTH 348 Query: 485 HDEGVTCLAWLGSSRYVASGCIDG-MVRIWDSLSGDLARTFSGHRDVVQSLAVSAD 321 H + V LA + AS G ++ W G F GH ++ +L+++++ Sbjct: 349 HKKSVRALAIHPTEYSFASASSGGNNIKKWKCPEGIFVNNFVGHEAIINTLSINSE 404 Score = 43.5 bits (101), Expect = 6e-04 Identities = 23/77 (29%), Positives = 41/77 (53%) Frame = -2 Query: 485 HDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIV 306 H V +A +++ A+G D +++IWD SG+L + +GH ++ LAVS + Sbjct: 181 HMGWVRAVAMDPGNQWFATGAGDRVIKIWDLASGELKLSLTGHISTIRGLAVSDRHPYLF 240 Query: 305 SVSTDKSARVFDISMFK 255 S + DK + +D+ K Sbjct: 241 SCAEDKMVKCWDLETNK 257
>EBI_DROME (Q95RJ9) F-box-like/WD repeat protein ebi| Length = 700 Score = 58.9 bits (141), Expect = 1e-08 Identities = 36/139 (25%), Positives = 61/139 (43%), Gaps = 10/139 (7%) Frame = -2 Query: 659 VHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLAR-QAIRSTCEH 483 +H+ + + + + GHTN + I + +A+ S D TL IW + R + H Sbjct: 516 IHVCRLGVNEPIKTFKGHTNEVNAIKWCPQGQLLASCSDDMTLKIWSMNRDRCCHDLQAH 575 Query: 482 DEGVTCLAWL---------GSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAV 330 + + + W ++ +AS D VR+WD G T + H + V S+A Sbjct: 576 SKEIYTIKWSPTGPGTNNPNTNLILASASFDSTVRLWDVERGSCIHTLTKHTEPVYSVAF 635 Query: 329 SADGNSIVSVSTDKSARVF 273 S DG + S S DK ++ Sbjct: 636 SPDGKHLASGSFDKCVHIW 654 Score = 52.8 bits (125), Expect = 9e-07 Identities = 39/132 (29%), Positives = 59/132 (44%), Gaps = 14/132 (10%) Frame = -2 Query: 617 LVGHTNSIECIGISSRYNWVATGSIDRTLIIWDL------ARQAIRSTCEHDEG------ 474 L GH + + + + +A+GS D T IWD+ + Q + C G Sbjct: 351 LRGHESEVFICAWNPSRDLLASGSGDSTARIWDMSDANTNSNQLVLRHCIQKGGAEVPSN 410 Query: 473 --VTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSV 300 VT L W +A+G DG RIW + G LA T H+ + +L + GN I+S Sbjct: 411 KDVTSLDWNCDGSLLATGSYDGYARIWKT-DGRLASTLGQHKGPIFALKWNKCGNYILSA 469 Query: 299 STDKSARVFDIS 264 DK+ ++D S Sbjct: 470 GVDKTTIIWDAS 481 Score = 51.2 bits (121), Expect = 3e-06 Identities = 28/102 (27%), Positives = 54/102 (52%), Gaps = 1/102 (0%) Frame = -2 Query: 560 VATGSIDRTLIIWDLAR-QAIRSTCEHDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSG 384 +A+ S D T+ +WD+ R I + +H E V +A+ +++ASG D V IW + +G Sbjct: 600 LASASFDSTVRLWDVERGSCIHTLTKHTEPVYSVAFSPDGKHLASGSFDKCVHIWSTQTG 659 Query: 383 DLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFDISMF 258 L ++ G + + + ++ G + + ++D S V D+ F Sbjct: 660 QLVHSYKGTGGIFE-VCWNSKGTKVGASASDGSVFVLDLRKF 700 Score = 40.0 bits (92), Expect = 0.006 Identities = 26/125 (20%), Positives = 55/125 (44%), Gaps = 1/125 (0%) Frame = -2 Query: 635 GQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLAR-QAIRSTCEHDEGVTCLA 459 G++ +L H I + + N++ + +D+T IIWD + Q + H + Sbjct: 441 GRLASTLGQHKGPIFALKWNKCGNYILSAGVDKTTIIWDASTGQCTQQFAFHSAPALDVD 500 Query: 458 WLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSAR 279 W + + AS D + + + +TF GH + V ++ G + S S D + + Sbjct: 501 WQTNQAF-ASCSTDQRIHVCRLGVNEPIKTFKGHTNEVNAIKWCPQGQLLASCSDDMTLK 559 Query: 278 VFDIS 264 ++ ++ Sbjct: 560 IWSMN 564 Score = 38.9 bits (89), Expect = 0.014 Identities = 27/96 (28%), Positives = 41/96 (42%), Gaps = 1/96 (1%) Frame = -2 Query: 560 VATGSIDRTLIIWDLARQAIRSTCEHDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGD 381 +ATGS D IW + + +H + L W Y+ S +D IWD+ +G Sbjct: 425 LATGSYDGYARIWKTDGRLASTLGQHKGPIFALKWNKCGNYILSAGVDKTTIIWDASTGQ 484 Query: 380 LARTFSGHRDVVQSLAVSADGN-SIVSVSTDKSARV 276 + F+ H +L V N + S STD+ V Sbjct: 485 CTQQFAFHS--APALDVDWQTNQAFASCSTDQRIHV 518 Score = 35.4 bits (80), Expect = 0.15 Identities = 19/89 (21%), Positives = 37/89 (41%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCEH 483 +V + + G + +L HT + + S +A+GS D+ + IW + + + Sbjct: 608 TVRLWDVERGSCIHTLTKHTEPVYSVAFSPDGKHLASGSFDKCVHIWSTQTGQLVHSYKG 667 Query: 482 DEGVTCLAWLGSSRYVASGCIDGMVRIWD 396 G+ + W V + DG V + D Sbjct: 668 TGGIFEVCWNSKGTKVGASASDGSVFVLD 696
>PRP4_YEAST (P20053) U4/U6 small nuclear ribonucleoprotein PRP4| Length = 465 Score = 58.9 bits (141), Expect = 1e-08 Identities = 35/123 (28%), Positives = 59/123 (47%), Gaps = 1/123 (0%) Frame = -2 Query: 632 QVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLA-RQAIRSTCEHDEGVTCLAW 456 +++G LVGH I + ++ + S D T +WD + Q + HD+GV L++ Sbjct: 256 RLLGDLVGHERRISDVKYHPSGKFIGSASHDMTWRLWDASTHQELLLQEGHDKGVFSLSF 315 Query: 455 LGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARV 276 V SG +D + +WD SG T +GH + ++A S +G + + D V Sbjct: 316 QCDGSLVCSGGMDSLSMLWDIRSGSKVMTLAGHSKPIYTVAWSPNGYQVATGGGDGIINV 375 Query: 275 FDI 267 +DI Sbjct: 376 WDI 378 Score = 46.2 bits (108), Expect = 9e-05 Identities = 34/131 (25%), Positives = 64/131 (48%), Gaps = 6/131 (4%) Frame = -2 Query: 644 INSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQ---AIRSTCEHDEG 474 I SG V +L GH+ I + S VATG D + +WD+ ++ + H Sbjct: 336 IRSGSKVMTLAGHSKPIYTVAWSPNGYQVATGGGDGIINVWDIRKRDEGQLNQILAHRNI 395 Query: 473 VTCLAWL---GSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVS 303 VT + + G + V+ G D ++ ++ S + + +GH D + SL +S + + +VS Sbjct: 396 VTQVRFSKEDGGKKLVSCG-YDNLINVYSSDTWLKMGSLAGHTDKIISLDISNNSHFLVS 454 Query: 302 VSTDKSARVFD 270 D+S ++++ Sbjct: 455 GGWDRSIKLWN 465 Score = 35.0 bits (79), Expect = 0.20 Identities = 14/47 (29%), Positives = 31/47 (65%) Frame = -2 Query: 659 VHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWD 519 +++ S ++ +GSL GHT+ I + IS+ +++ +G DR++ +W+ Sbjct: 419 INVYSSDTWLKMGSLAGHTDKIISLDISNNSHFLVSGGWDRSIKLWN 465
>PRP46_YEAST (Q12417) Pre-mRNA-splicing factor PRP46 (Pre-mRNA-processing| protein 46) (Complexed with CEF1 protein 1) (PRP19-associated complex protein 50) (PRP nineteen-associated complex protein 50) Length = 451 Score = 58.5 bits (140), Expect = 2e-08 Identities = 32/133 (24%), Positives = 70/133 (52%), Gaps = 1/133 (0%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLAR-QAIRSTCE 486 ++ + + +G++ +L GH ++ + +S R+ ++ + S D+T+ WDL + Q IR Sbjct: 163 TMKVWDLATGKLKTTLAGHVMTVRDVAVSDRHPYLFSVSEDKTVKCWDLEKNQIIRDYYG 222 Query: 485 HDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIV 306 H GV ++ + +A+ D ++++WD + T GH+ + + + +V Sbjct: 223 HLSGVRTVSIHPTLDLIATAGRDSVIKLWDMRTRIPVITLVGHKGPINQVQCTPVDPQVV 282 Query: 305 SVSTDKSARVFDI 267 S STD + R++D+ Sbjct: 283 SSSTDATVRLWDV 295 Score = 51.2 bits (121), Expect = 3e-06 Identities = 32/117 (27%), Positives = 55/117 (47%), Gaps = 2/117 (1%) Frame = -2 Query: 611 GHTNSIECIGISSRYN-WVATGSIDRTLIIWDLARQAIRST-CEHDEGVTCLAWLGSSRY 438 GH + C+ I N W TGS D T+ +WDLA +++T H V +A Y Sbjct: 137 GHLGWVRCVAIDPVDNEWFITGSNDTTMKVWDLATGKLKTTLAGHVMTVRDVAVSDRHPY 196 Query: 437 VASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFDI 267 + S D V+ WD + R + GH V+++++ + I + D +++D+ Sbjct: 197 LFSVSEDKTVKCWDLEKNQIIRDYYGHLSGVRTVSIHPTLDLIATAGRDSVIKLWDM 253 Score = 39.7 bits (91), Expect = 0.008 Identities = 28/105 (26%), Positives = 48/105 (45%), Gaps = 5/105 (4%) Frame = -2 Query: 620 SLVGHT---NSIECIGISSRYNWVATGSIDRTLIIWD-LARQAIRSTCEHDEGVTCLAWL 453 +LVGH N ++C + + V + S D T+ +WD +A + ++ H V A Sbjct: 261 TLVGHKGPINQVQCTPVDPQ---VVSSSTDATVRLWDVVAGKTMKVLTHHKRSVRATALH 317 Query: 452 GSSRYVASGCIDGMVRIWDSLSGDLARTFSGHR-DVVQSLAVSAD 321 VAS C D +R W G L F + ++ +L+++ D Sbjct: 318 PKEFSVASACTDD-IRSWGLAEGSLLTNFESEKTGIINTLSINQD 361
>WD51B_HUMAN (Q8TC44) WD-repeat protein 51B| Length = 478 Score = 58.5 bits (140), Expect = 2e-08 Identities = 43/167 (25%), Positives = 73/167 (43%), Gaps = 3/167 (1%) Frame = -2 Query: 608 HTNSIECIGISSRYNWVATGSIDRTLIIWDLARQA-IRSTCEHDEGVTCLAWLGSSRYVA 432 HT + + S+ ++AT S D+++ +W + RQ + S H V C + R + Sbjct: 101 HTAPVRSVDFSADGQFLATASEDKSIKVWSMYRQRFLYSLYRHTHWVRCAKFSPDGRLIV 160 Query: 431 SGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFDISMFK* 252 S D ++IWD+ + FS + + G I S +D++ +V+D+ + K Sbjct: 161 SCSEDKTIKIWDTTNKQCVNNFSDSVGFANFVDFNPSGTCIASAGSDQTVKVWDVRVNK- 219 Query: 251 EKS*QQQHG*FGWSFWPVKSGGL--LSLYGQELYLQACSHHGALKTL 117 QH + V SGG+ +S + YL S G LK L Sbjct: 220 ----LLQH-------YQVHSGGVNCISFHPSGNYLITASSDGTLKIL 255 Score = 49.3 bits (116), Expect = 1e-05 Identities = 30/133 (22%), Positives = 62/133 (46%), Gaps = 1/133 (0%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLA-RQAIRSTCE 486 S+ + S+ + + SL HT+ + C S + + S D+T+ IWD +Q + + + Sbjct: 125 SIKVWSMYRQRFLYSLYRHTHWVRCAKFSPDGRLIVSCSEDKTIKIWDTTNKQCVNNFSD 184 Query: 485 HDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIV 306 + + S +AS D V++WD L + + H V ++ GN ++ Sbjct: 185 SVGFANFVDFNPSGTCIASAGSDQTVKVWDVRVNKLLQHYQVHSGGVNCISFHPSGNYLI 244 Query: 305 SVSTDKSARVFDI 267 + S+D + ++ D+ Sbjct: 245 TASSDGTLKILDL 257 Score = 48.1 bits (113), Expect = 2e-05 Identities = 26/91 (28%), Positives = 45/91 (49%), Gaps = 1/91 (1%) Frame = -2 Query: 560 VATGSIDRTLIIWDL-ARQAIRSTCEHDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSG 384 +A+ D+T+ +WD+ + ++ H GV C+++ S Y+ + DG ++I D L G Sbjct: 201 IASAGSDQTVKVWDVRVNKLLQHYQVHSGGVNCISFHPSGNYLITASSDGTLKILDLLEG 260 Query: 383 DLARTFSGHRDVVQSLAVSADGNSIVSVSTD 291 L T GH V +++ S G S D Sbjct: 261 RLIYTLQGHTGPVFTVSFSKGGELFASGGAD 291 Score = 47.8 bits (112), Expect = 3e-05 Identities = 33/116 (28%), Positives = 52/116 (44%), Gaps = 1/116 (0%) Frame = -2 Query: 611 GHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQA-IRSTCEHDEGVTCLAWLGSSRYV 435 GH +I + +S +AT S D L++W+ A H + VT + + + Sbjct: 16 GHKAAITSLDLSPNGKQLATASWDTFLMLWNFKPHARAYRYVGHKDVVTSVQFSPHGNLL 75 Query: 434 ASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFDI 267 AS D VR+W F H V+S+ SADG + + S DKS +V+ + Sbjct: 76 ASASRDRTVRLWIPDKRGKFSEFKAHTAPVRSVDFSADGQFLATASEDKSIKVWSM 131 Score = 46.2 bits (108), Expect = 9e-05 Identities = 29/116 (25%), Positives = 54/116 (46%), Gaps = 1/116 (0%) Frame = -2 Query: 614 VGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCE-HDEGVTCLAWLGSSRY 438 VGH + + + S N +A+ S DRT+ +W ++ S + H V + + ++ Sbjct: 57 VGHKDVVTSVQFSPHGNLLASASRDRTVRLWIPDKRGKFSEFKAHTAPVRSVDFSADGQF 116 Query: 437 VASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFD 270 +A+ D +++W + H V+ S DG IVS S DK+ +++D Sbjct: 117 LATASEDKSIKVWSMYRQRFLYSLYRHTHWVRCAKFSPDGRLIVSCSEDKTIKIWD 172
>GBLP_NEUCR (Q01369) Guanine nucleotide-binding protein beta subunit-like| protein (Cross-pathway control WD-repeat protein cpc-2) Length = 316 Score = 58.5 bits (140), Expect = 2e-08 Identities = 38/125 (30%), Positives = 60/125 (48%), Gaps = 7/125 (5%) Frame = -2 Query: 623 GSLVGHTNSIECIGIS-SRYNWVATGSIDRTLIIWDLARQAI------RSTCEHDEGVTC 465 G+L GH + + S N + +GS D++LIIW+L R R H V+ Sbjct: 9 GTLEGHNGWVTSLATSLENPNMLLSGSRDKSLIIWNLTRDETSYGYPKRRLHGHSHIVSD 68 Query: 464 LAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKS 285 Y S D +R+W+ +G R F GH + V S++ SAD IVS S D++ Sbjct: 69 CVISSDGAYALSASWDKTLRLWELSTGTTTRRFVGHTNDVLSVSFSADNRQIVSGSRDRT 128 Query: 284 ARVFD 270 ++++ Sbjct: 129 IKLWN 133 Score = 57.4 bits (137), Expect = 4e-08 Identities = 33/140 (23%), Positives = 68/140 (48%), Gaps = 4/140 (2%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCE- 486 ++ + +++G VGHTN + + S+ + +GS DRT+ +W+ + E Sbjct: 86 TLRLWELSTGTTTRRFVGHTNDVLSVSFSADNRQIVSGSRDRTIKLWNTLGDCKFTITEK 145 Query: 485 -HDEGVTCLAWLGSSR--YVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGN 315 H E V+C+ + + + + S D +V++W+ S L GH + ++ +S DG+ Sbjct: 146 GHTEWVSCVRFSPNPQNPVIVSSGWDKLVKVWELSSCKLQTDHIGHTGYINAVTISPDGS 205 Query: 314 SIVSVSTDKSARVFDISMFK 255 S D + ++D++ K Sbjct: 206 LCASGGKDGTTMLWDLNESK 225 Score = 35.0 bits (79), Expect = 0.20 Identities = 33/140 (23%), Positives = 58/140 (41%), Gaps = 9/140 (6%) Frame = -2 Query: 659 VHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCEHD 480 V + ++S ++ +GHT I + IS + A+G D T ++WDL + + Sbjct: 174 VKVWELSSCKLQTDHIGHTGYINAVTISPDGSLCASGGKDGTTMLWDLNESKHLYSLNAN 233 Query: 479 EGVTCLAWLGSSRYVASGCIDGMVRIWD----SLSGDLARTFSG-----HRDVVQSLAVS 327 + + L + +RY + I+D S +L F SLA S Sbjct: 234 DEIHALVF-SPNRYWLCAATSSSIIIFDLEKKSKVDELKPEFQNIGKKSREPECVSLAWS 292 Query: 326 ADGNSIVSVSTDKSARVFDI 267 ADG ++ + TD R + + Sbjct: 293 ADGQTLFAGYTDNIIRAWGV 312
>GBB_LYMST (Q08706) Guanine nucleotide-binding protein beta subunit| Length = 341 Score = 58.5 bits (140), Expect = 2e-08 Identities = 39/135 (28%), Positives = 60/135 (44%), Gaps = 3/135 (2%) Frame = -2 Query: 662 SVHIVSINSGQVVGS--LVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLAR-QAIRST 492 S++ + G V S L GHT + C N + T S D + +WD+ Q S Sbjct: 123 SIYSLKTREGNVRVSRELPGHTGYLSCCRFIDD-NSIVTSSGDMSCALWDIETGQQTTSF 181 Query: 491 CEHDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNS 312 H V L+ R SG D ++WD G +TFSGH + ++ +G++ Sbjct: 182 TGHTGDVMSLSTSPDFRTFVSGACDASAKLWDVRDGMCKQTFSGHESDINAITYFPNGHA 241 Query: 311 IVSVSTDKSARVFDI 267 + S D + R+FDI Sbjct: 242 FATGSDDATCRLFDI 256 Score = 50.1 bits (118), Expect = 6e-06 Identities = 33/134 (24%), Positives = 58/134 (43%), Gaps = 3/134 (2%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCEH 483 S + + G + GH + I I + ATGS D T ++D+ H Sbjct: 208 SAKLWDVRDGMCKQTFSGHESDINAITYFPNGHAFATGSDDATCRLFDIRADQEIGMYSH 267 Query: 482 DE---GVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNS 312 D G+T +A+ S R + D +WD L + +GH + V L V+ DG++ Sbjct: 268 DNIICGITSVAFSKSGRLLLGRYDDFNCNVWDVLKQETHGVLAGHDNRVSCLGVTEDGSA 327 Query: 311 IVSVSTDKSARVFD 270 + + S D ++++ Sbjct: 328 VATGSWDSFLKIWN 341 Score = 37.0 bits (84), Expect = 0.053 Identities = 33/123 (26%), Positives = 54/123 (43%), Gaps = 5/123 (4%) Frame = -2 Query: 620 SLVGHTNSIECIGISSRYNWVATGSIDRTLIIWD-LARQAIRSTCEHDEGVTCLAWLGSS 444 +L GH I + +S + + S D LI+WD + + V A+ S Sbjct: 51 TLRGHLAKIYAMHWASDSRNLVSASQDGKLIVWDGYTTNKVHAIPLRSSWVMTCAYAPSG 110 Query: 443 RYVASGCIDGMVRIWDSLSGD----LARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARV 276 +VA G +D + I+ + + ++R GH + S D NSIV+ S D S + Sbjct: 111 NFVACGGLDNICSIYSLKTREGNVRVSRELPGHTGYL-SCCRFIDDNSIVTSSGDMSCAL 169 Query: 275 FDI 267 +DI Sbjct: 170 WDI 172
>GBB4_RAT (O35353) Guanine nucleotide-binding protein beta subunit 4| (Transducin beta chain 4) Length = 339 Score = 58.5 bits (140), Expect = 2e-08 Identities = 38/128 (29%), Positives = 58/128 (45%), Gaps = 3/128 (2%) Frame = -2 Query: 644 INSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCEHDE---G 474 I G S GH + I + ATGS D T ++DL HD G Sbjct: 212 IRDGMCRQSFTGHISDINAVSFFPSGYAFATGSDDATCRLFDLRADQELLLYSHDNIICG 271 Query: 473 VTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVST 294 +T +A+ S R + +G D +WD+L G A +GH + V L V+ DG ++ + S Sbjct: 272 ITSVAFSKSGRLLLAGYDDFNCSVWDALKGGRAGVLAGHDNRVSCLGVTDDGMAVATGSW 331 Query: 293 DKSARVFD 270 D R+++ Sbjct: 332 DSFLRIWN 339 Score = 48.5 bits (114), Expect = 2e-05 Identities = 31/123 (25%), Positives = 53/123 (43%), Gaps = 1/123 (0%) Frame = -2 Query: 632 QVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLAR-QAIRSTCEHDEGVTCLAW 456 +V L GHT + C + T S D T +WD+ Q + H V L+ Sbjct: 133 RVSRELPGHTGYLSCCRFLDD-GQIITSSGDTTCALWDIETGQQTTTFTGHSGDVMSLSL 191 Query: 455 LGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARV 276 + SG D ++WD G ++F+GH + +++ G + + S D + R+ Sbjct: 192 SPDLKTFVSGACDASSKLWDIRDGMCRQSFTGHISDINAVSFFPSGYAFATGSDDATCRL 251 Query: 275 FDI 267 FD+ Sbjct: 252 FDL 254 Score = 47.8 bits (112), Expect = 3e-05 Identities = 32/105 (30%), Positives = 55/105 (52%), Gaps = 5/105 (4%) Frame = -2 Query: 566 NWVATGSIDRTLIIWDLARQA--IRSTCE---HDEGVTCLAWLGSSRYVASGCIDGMVRI 402 N+VA G +D I++L + +R + E H ++C +L + + S D + Sbjct: 109 NYVACGGLDNICSIYNLKTREGNVRVSRELPGHTGYLSCCRFLDDGQIITSSG-DTTCAL 167 Query: 401 WDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFDI 267 WD +G TF+GH V SL++S D + VS + D S++++DI Sbjct: 168 WDIETGQQTTTFTGHSGDVMSLSLSPDLKTFVSGACDASSKLWDI 212
>PF20_CHLRE (P93107) Flagellar WD-repeat protein PF20| Length = 606 Score = 58.5 bits (140), Expect = 2e-08 Identities = 37/138 (26%), Positives = 64/138 (46%), Gaps = 4/138 (2%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDL----ARQAIRS 495 +V I + V + H +I + VA+GS+D T+ +WDL R A+R Sbjct: 391 AVKIWDFEKQRCVTTFTDHKQAIWSVRFHHLGEVVASGSLDHTVRLWDLPAGKCRMALRG 450 Query: 494 TCEHDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGN 315 H + V LAW S +A+ D V +WD+ +G +T+ GH++ ++ + G Sbjct: 451 ---HVDSVNDLAWQPFSSSLATASSDKTVSVWDARAGLCTQTYYGHQNSCNGVSFNILGT 507 Query: 314 SIVSVSTDKSARVFDISM 261 + S D +++D M Sbjct: 508 QLASTDADGVVKLWDTRM 525 Score = 57.0 bits (136), Expect = 5e-08 Identities = 33/115 (28%), Positives = 55/115 (47%), Gaps = 1/115 (0%) Frame = -2 Query: 611 GHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRST-CEHDEGVTCLAWLGSSRYV 435 GH + + + +A+G D + IWD +Q +T +H + + + + V Sbjct: 366 GHKDWVAGVDFHPAGTCLASGGGDSAVKIWDFEKQRCVTTFTDHKQAIWSVRFHHLGEVV 425 Query: 434 ASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFD 270 ASG +D VR+WD +G GH D V LA +S+ + S+DK+ V+D Sbjct: 426 ASGSLDHTVRLWDLPAGKCRMALRGHVDSVNDLAWQPFSSSLATASSDKTVSVWD 480 Score = 50.1 bits (118), Expect = 6e-06 Identities = 33/133 (24%), Positives = 59/133 (44%), Gaps = 3/133 (2%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDL---ARQAIRST 492 +V + +G + GH NS + + +A+ D + +WD A A +T Sbjct: 475 TVSVWDARAGLCTQTYYGHQNSCNGVSFNILGTQLASTDADGVVKLWDTRMTAEVATINT 534 Query: 491 CEHDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNS 312 +H +C S + +A C DG V+ + + G L +GH D VQ++ G Sbjct: 535 GKHPANKSCFD--RSGQVLAVACDDGKVKAYSTTDGVLQAELAGHEDAVQAVLFDPAGQY 592 Query: 311 IVSVSTDKSARVF 273 +VS +D + R++ Sbjct: 593 LVSCGSDNTFRLW 605 Score = 41.2 bits (95), Expect = 0.003 Identities = 29/116 (25%), Positives = 52/116 (44%), Gaps = 1/116 (0%) Frame = -2 Query: 611 GHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCE-HDEGVTCLAWLGSSRYV 435 GH S+ + + + T S D+T +W + + E H + V + + + + Sbjct: 324 GHLLSVANLALHPTKPILVTASDDKTWKMWHMPGGDLIMCGEGHKDWVAGVDFHPAGTCL 383 Query: 434 ASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFDI 267 ASG D V+IWD TF+ H+ + S+ G + S S D + R++D+ Sbjct: 384 ASGGGDSAVKIWDFEKQRCVTTFTDHKQAIWSVRFHHLGEVVASGSLDHTVRLWDL 439
>PRP46_CANGA (Q6FJZ9) Pre-mRNA-splicing factor PRP46 (Pre-mRNA-processing| protein 46) Length = 427 Score = 58.5 bits (140), Expect = 2e-08 Identities = 37/117 (31%), Positives = 56/117 (47%), Gaps = 2/117 (1%) Frame = -2 Query: 611 GHTNSIECIGISSRYN-WVATGSIDRTLIIWDLARQAIRSTCE-HDEGVTCLAWLGSSRY 438 GH + CI + N W ATGS D+T+ IW+LA ++ T + HD V LA Y Sbjct: 113 GHHGWVRCIAMDKVDNEWFATGSNDKTIKIWNLASGKLKVTLKAHDMTVRDLAISNRHPY 172 Query: 437 VASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFDI 267 + S D V+ WD R + GH V ++ + + +V+ D +V+DI Sbjct: 173 MFSVSEDKTVKCWDLEKNTAIRNYHGHLSGVHTVDIHPTVDVVVTAGRDSVVKVWDI 229 Score = 52.8 bits (125), Expect = 9e-07 Identities = 34/133 (25%), Positives = 68/133 (51%), Gaps = 1/133 (0%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQ-AIRSTCE 486 ++ I ++ SG++ +L H ++ + IS+R+ ++ + S D+T+ WDL + AIR+ Sbjct: 139 TIKIWNLASGKLKVTLKAHDMTVRDLAISNRHPYMFSVSEDKTVKCWDLEKNTAIRNYHG 198 Query: 485 HDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIV 306 H GV + + V + D +V++WD + T GH+ + + ++ Sbjct: 199 HLSGVHTVDIHPTVDVVVTAGRDSVVKVWDIRTRLPVMTLPGHKGPITKVRCLPVDPQVI 258 Query: 305 SVSTDKSARVFDI 267 S S D S R++D+ Sbjct: 259 SSSVDASIRLWDL 271
>PRP46_ASPFU (Q4WT34) Pre-mRNA-splicing factor prp46 (Pre-mRNA-processing| protein 46) Length = 453 Score = 58.2 bits (139), Expect = 2e-08 Identities = 38/116 (32%), Positives = 58/116 (50%), Gaps = 1/116 (0%) Frame = -2 Query: 611 GHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCE-HDEGVTCLAWLGSSRYV 435 GH + + + W A+G+ DRT+ IW+LA A+R T H V LA Y+ Sbjct: 142 GHLGWVRSLAVEPNNEWFASGAGDRTIKIWNLATGALRLTLTGHISTVRGLAVSPRHPYL 201 Query: 434 ASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFDI 267 S D MV+ WD + + R + GH V +LA+ + +V+ D ARV+D+ Sbjct: 202 FSCGEDKMVKCWDLETNKVIRHYHGHLSGVYTLALHPRLDLLVTGGRDGVARVWDM 257 Score = 57.0 bits (136), Expect = 5e-08 Identities = 35/137 (25%), Positives = 67/137 (48%), Gaps = 1/137 (0%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDL-ARQAIRSTCE 486 ++ I ++ +G + +L GH +++ + +S R+ ++ + D+ + WDL + IR Sbjct: 167 TIKIWNLATGALRLTLTGHISTVRGLAVSPRHPYLFSCGEDKMVKCWDLETNKVIRHYHG 226 Query: 485 HDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIV 306 H GV LA + +G DG+ R+WD + SGH+ V L I+ Sbjct: 227 HLSGVYTLALHPRLDLLVTGGRDGVARVWDMRTRSNIHVLSGHKGTVADLKCQEADPQII 286 Query: 305 SVSTDKSARVFDISMFK 255 + S D + R++D++ K Sbjct: 287 TGSLDATVRLWDLAAGK 303 Score = 51.6 bits (122), Expect = 2e-06 Identities = 30/100 (30%), Positives = 48/100 (48%), Gaps = 1/100 (1%) Frame = -2 Query: 617 LVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLAR-QAIRSTCEHDEGVTCLAWLGSSR 441 L GH ++ + + TGS+D T+ +WDLA + + H +GV LA + Sbjct: 266 LSGHKGTVADLKCQEADPQIITGSLDATVRLWDLAAGKTMGVLTHHKKGVRNLA-IHPRE 324 Query: 440 YVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSAD 321 + + G ++ W GD + F GH V+ SLAV+ D Sbjct: 325 FTFASASTGSIKQWKCPEGDFMQNFEGHNAVINSLAVNED 364 Score = 42.4 bits (98), Expect = 0.001 Identities = 27/90 (30%), Positives = 42/90 (46%) Frame = -2 Query: 524 WDLARQAIRSTCEHDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVV 345 W + +R H V LA ++ + ASG D ++IW+ +G L T +GH V Sbjct: 130 WHPPWKLMRVISGHLGWVRSLAVEPNNEWFASGAGDRTIKIWNLATGALRLTLTGHISTV 189 Query: 344 QSLAVSADGNSIVSVSTDKSARVFDISMFK 255 + LAVS + S DK + +D+ K Sbjct: 190 RGLAVSPRHPYLFSCGEDKMVKCWDLETNK 219
>PRP46_EMENI (Q5BE22) Pre-mRNA-splicing factor prp46 (Pre-mRNA-processing| protein 46) Length = 452 Score = 58.2 bits (139), Expect = 2e-08 Identities = 38/116 (32%), Positives = 58/116 (50%), Gaps = 1/116 (0%) Frame = -2 Query: 611 GHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCE-HDEGVTCLAWLGSSRYV 435 GH + + + W A+G+ DRT+ IW+LA A+R T H V LA Y+ Sbjct: 141 GHLGWVRSLAVEPNNEWFASGAGDRTIKIWNLATGALRLTLTGHISTVRGLAVSPRHPYL 200 Query: 434 ASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFDI 267 S D MV+ WD + + R + GH V +LA+ + +V+ D ARV+D+ Sbjct: 201 FSCGEDKMVKCWDLETNKVIRHYHGHLSGVYTLALHPRLDLLVTGGRDGVARVWDM 256 Score = 54.3 bits (129), Expect = 3e-07 Identities = 33/137 (24%), Positives = 66/137 (48%), Gaps = 1/137 (0%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDL-ARQAIRSTCE 486 ++ I ++ +G + +L GH +++ + +S R+ ++ + D+ + WDL + IR Sbjct: 166 TIKIWNLATGALRLTLTGHISTVRGLAVSPRHPYLFSCGEDKMVKCWDLETNKVIRHYHG 225 Query: 485 HDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIV 306 H GV LA + +G DG+ R+WD + SGH V + ++ Sbjct: 226 HLSGVYTLALHPRLDLLVTGGRDGVARVWDMRTRSNIHVLSGHTGTVADVQCQEADPQVI 285 Query: 305 SVSTDKSARVFDISMFK 255 + S D + R++D++ K Sbjct: 286 TGSLDATVRLWDLAAGK 302 Score = 46.2 bits (108), Expect = 9e-05 Identities = 28/118 (23%), Positives = 51/118 (43%), Gaps = 1/118 (0%) Frame = -2 Query: 644 INSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDL-ARQAIRSTCEHDEGVT 468 + + +V+ GH + + + + R + + TG D +WD+ R I H V Sbjct: 214 LETNKVIRHYHGHLSGVYTLALHPRLDLLVTGGRDGVARVWDMRTRSNIHVLSGHTGTVA 273 Query: 467 CLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVST 294 + + V +G +D VR+WD +G + H+ ++SLA + S ST Sbjct: 274 DVQCQEADPQVITGSLDATVRLWDLAAGKTMGVLTHHKKGIRSLATHPREFTFASAST 331 Score = 43.1 bits (100), Expect = 7e-04 Identities = 27/90 (30%), Positives = 42/90 (46%) Frame = -2 Query: 524 WDLARQAIRSTCEHDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVV 345 W + +R H V LA ++ + ASG D ++IW+ +G L T +GH V Sbjct: 129 WHAPWKLMRVISGHLGWVRSLAVEPNNEWFASGAGDRTIKIWNLATGALRLTLTGHISTV 188 Query: 344 QSLAVSADGNSIVSVSTDKSARVFDISMFK 255 + LAVS + S DK + +D+ K Sbjct: 189 RGLAVSPRHPYLFSCGEDKMVKCWDLETNK 218
>GBB2_RAT (P54313) Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta| subunit 2 (Transducin beta chain 2) (G protein beta 2 subunit) Length = 339 Score = 58.2 bits (139), Expect = 2e-08 Identities = 35/134 (26%), Positives = 61/134 (45%), Gaps = 3/134 (2%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCEH 483 S+ + + + +GH + I + TGS D T ++DL H Sbjct: 206 SIKLWDVRDSMCRQTFIGHESDINAVAFFPNGYAFTTGSDDATCRLFDLRADQELLMYSH 265 Query: 482 DE---GVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNS 312 D G+T +A+ S R + +G D IWD++ GD A +GH + V L V+ DG + Sbjct: 266 DNIICGITSVAFSRSGRLLLAGYDDFNCNIWDAMKGDRAGVLAGHDNRVSCLGVTDDGMA 325 Query: 311 IVSVSTDKSARVFD 270 + + S D ++++ Sbjct: 326 VATGSWDSFLKIWN 339 Score = 55.5 bits (132), Expect = 1e-07 Identities = 37/135 (27%), Positives = 58/135 (42%), Gaps = 3/135 (2%) Frame = -2 Query: 662 SVHIVSINSGQVVGS--LVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLAR-QAIRST 492 S++ + G V S L GHT + C N + T S D T +WD+ Q Sbjct: 121 SIYSLKTREGNVRVSRELPGHTGYLSCCRFLDD-NQIITSSGDTTCALWDIETGQQTVGF 179 Query: 491 CEHDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNS 312 H V L+ R SG D +++WD +TF GH + ++A +G + Sbjct: 180 AGHSGDVMSLSLAPDGRTFVSGACDASIKLWDVRDSMCRQTFIGHESDINAVAFFPNGYA 239 Query: 311 IVSVSTDKSARVFDI 267 + S D + R+FD+ Sbjct: 240 FTTGSDDATCRLFDL 254 Score = 35.4 bits (80), Expect = 0.15 Identities = 37/164 (22%), Positives = 59/164 (35%), Gaps = 46/164 (28%) Frame = -2 Query: 620 SLVGHTNSIECIGISSRYNWVATGSIDRTLIIWD-LARQAIRSTCEHDEGVTCLAWLGSS 444 +L GH I + + + + S D LIIWD + + V A+ S Sbjct: 49 TLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSG 108 Query: 443 RYVASGCID------------GMVRI---------------------------------W 399 +VA G +D G VR+ W Sbjct: 109 NFVACGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFLDDNQIITSSGDTTCALW 168 Query: 398 DSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFDI 267 D +G F+GH V SL+++ DG + VS + D S +++D+ Sbjct: 169 DIETGQQTVGFAGHSGDVMSLSLAPDGRTFVSGACDASIKLWDV 212
>GBB2_MOUSE (P62880) Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta| subunit 2 (Transducin beta chain 2) (G protein beta 2 subunit) Length = 339 Score = 58.2 bits (139), Expect = 2e-08 Identities = 35/134 (26%), Positives = 61/134 (45%), Gaps = 3/134 (2%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCEH 483 S+ + + + +GH + I + TGS D T ++DL H Sbjct: 206 SIKLWDVRDSMCRQTFIGHESDINAVAFFPNGYAFTTGSDDATCRLFDLRADQELLMYSH 265 Query: 482 DE---GVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNS 312 D G+T +A+ S R + +G D IWD++ GD A +GH + V L V+ DG + Sbjct: 266 DNIICGITSVAFSRSGRLLLAGYDDFNCNIWDAMKGDRAGVLAGHDNRVSCLGVTDDGMA 325 Query: 311 IVSVSTDKSARVFD 270 + + S D ++++ Sbjct: 326 VATGSWDSFLKIWN 339 Score = 55.5 bits (132), Expect = 1e-07 Identities = 37/135 (27%), Positives = 58/135 (42%), Gaps = 3/135 (2%) Frame = -2 Query: 662 SVHIVSINSGQVVGS--LVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLAR-QAIRST 492 S++ + G V S L GHT + C N + T S D T +WD+ Q Sbjct: 121 SIYSLKTREGNVRVSRELPGHTGYLSCCRFLDD-NQIITSSGDTTCALWDIETGQQTVGF 179 Query: 491 CEHDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNS 312 H V L+ R SG D +++WD +TF GH + ++A +G + Sbjct: 180 AGHSGDVMSLSLAPDGRTFVSGACDASIKLWDVRDSMCRQTFIGHESDINAVAFFPNGYA 239 Query: 311 IVSVSTDKSARVFDI 267 + S D + R+FD+ Sbjct: 240 FTTGSDDATCRLFDL 254 Score = 35.4 bits (80), Expect = 0.15 Identities = 37/164 (22%), Positives = 59/164 (35%), Gaps = 46/164 (28%) Frame = -2 Query: 620 SLVGHTNSIECIGISSRYNWVATGSIDRTLIIWD-LARQAIRSTCEHDEGVTCLAWLGSS 444 +L GH I + + + + S D LIIWD + + V A+ S Sbjct: 49 TLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSG 108 Query: 443 RYVASGCID------------GMVRI---------------------------------W 399 +VA G +D G VR+ W Sbjct: 109 NFVACGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFLDDNQIITSSGDTTCALW 168 Query: 398 DSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFDI 267 D +G F+GH V SL+++ DG + VS + D S +++D+ Sbjct: 169 DIETGQQTVGFAGHSGDVMSLSLAPDGRTFVSGACDASIKLWDV 212
>GBB2_HUMAN (P62879) Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta| subunit 2 (Transducin beta chain 2) (G protein beta 2 subunit) Length = 339 Score = 58.2 bits (139), Expect = 2e-08 Identities = 35/134 (26%), Positives = 61/134 (45%), Gaps = 3/134 (2%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCEH 483 S+ + + + +GH + I + TGS D T ++DL H Sbjct: 206 SIKLWDVRDSMCRQTFIGHESDINAVAFFPNGYAFTTGSDDATCRLFDLRADQELLMYSH 265 Query: 482 DE---GVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNS 312 D G+T +A+ S R + +G D IWD++ GD A +GH + V L V+ DG + Sbjct: 266 DNIICGITSVAFSRSGRLLLAGYDDFNCNIWDAMKGDRAGVLAGHDNRVSCLGVTDDGMA 325 Query: 311 IVSVSTDKSARVFD 270 + + S D ++++ Sbjct: 326 VATGSWDSFLKIWN 339 Score = 55.5 bits (132), Expect = 1e-07 Identities = 37/135 (27%), Positives = 58/135 (42%), Gaps = 3/135 (2%) Frame = -2 Query: 662 SVHIVSINSGQVVGS--LVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLAR-QAIRST 492 S++ + G V S L GHT + C N + T S D T +WD+ Q Sbjct: 121 SIYSLKTREGNVRVSRELPGHTGYLSCCRFLDD-NQIITSSGDTTCALWDIETGQQTVGF 179 Query: 491 CEHDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNS 312 H V L+ R SG D +++WD +TF GH + ++A +G + Sbjct: 180 AGHSGDVMSLSLAPDGRTFVSGACDASIKLWDVRDSMCRQTFIGHESDINAVAFFPNGYA 239 Query: 311 IVSVSTDKSARVFDI 267 + S D + R+FD+ Sbjct: 240 FTTGSDDATCRLFDL 254 Score = 35.4 bits (80), Expect = 0.15 Identities = 37/164 (22%), Positives = 59/164 (35%), Gaps = 46/164 (28%) Frame = -2 Query: 620 SLVGHTNSIECIGISSRYNWVATGSIDRTLIIWD-LARQAIRSTCEHDEGVTCLAWLGSS 444 +L GH I + + + + S D LIIWD + + V A+ S Sbjct: 49 TLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSG 108 Query: 443 RYVASGCID------------GMVRI---------------------------------W 399 +VA G +D G VR+ W Sbjct: 109 NFVACGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFLDDNQIITSSGDTTCALW 168 Query: 398 DSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFDI 267 D +G F+GH V SL+++ DG + VS + D S +++D+ Sbjct: 169 DIETGQQTVGFAGHSGDVMSLSLAPDGRTFVSGACDASIKLWDV 212
>GBB_DICDI (P36408) Guanine nucleotide-binding protein beta subunit| Length = 347 Score = 58.2 bits (139), Expect = 2e-08 Identities = 36/123 (29%), Positives = 56/123 (45%), Gaps = 1/123 (0%) Frame = -2 Query: 632 QVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQA-IRSTCEHDEGVTCLAW 456 +V L HT + C + + T S D T I+WD+ I +H+ V ++ Sbjct: 141 RVCRELNSHTGYLSCCRFLNDRQ-IVTSSGDMTCILWDVENGTKITEFSDHNGDVMSVSV 199 Query: 455 LGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARV 276 Y SG D ++WD SG +TF+GH + ++ +G S + S D S R+ Sbjct: 200 SPDKNYFISGACDATAKLWDLRSGKCVQTFTGHEADINAVQYFPNGLSFGTGSDDASCRL 259 Query: 275 FDI 267 FDI Sbjct: 260 FDI 262 Score = 52.8 bits (125), Expect = 9e-07 Identities = 32/127 (25%), Positives = 58/127 (45%), Gaps = 3/127 (2%) Frame = -2 Query: 644 INSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCEHDE---G 474 + SG+ V + GH I + TGS D + ++D+ HD G Sbjct: 220 LRSGKCVQTFTGHEADINAVQYFPNGLSFGTGSDDASCRLFDIRADRELMQYTHDNILCG 279 Query: 473 VTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVST 294 +T + + S R++ +G D +WD+L G+ + +GH + V L V DG ++ + S Sbjct: 280 ITSVGFSFSGRFLFAGYDDFTCNVWDTLKGERVLSLTGHGNRVSCLGVPTDGMALCTGSW 339 Query: 293 DKSARVF 273 D +++ Sbjct: 340 DSLLKIW 346
>PRP46_ASHGO (Q75BY3) Pre-mRNA-splicing factor PRP46 (Pre-mRNA-processing| protein 46) Length = 425 Score = 58.2 bits (139), Expect = 2e-08 Identities = 38/117 (32%), Positives = 55/117 (47%), Gaps = 2/117 (1%) Frame = -2 Query: 611 GHTNSIECIGISSRYN-WVATGSIDRTLIIWDLARQAIRSTCE-HDEGVTCLAWLGSSRY 438 GHT + C+ + N W ATGS D T+ +WDLA ++ T + H V + Y Sbjct: 111 GHTGWVRCVCVDPVDNAWFATGSNDSTIRVWDLATGKLKVTLQGHIMTVRDICISARHPY 170 Query: 437 VASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFDI 267 + S D +V+ WD + R F G V S+ + + IVS D RV+DI Sbjct: 171 MFSASQDKLVKCWDLERNTVVRDFHGTLSGVHSVDLHPSLDLIVSAGRDSVVRVWDI 227 Score = 57.0 bits (136), Expect = 5e-08 Identities = 36/133 (27%), Positives = 66/133 (49%), Gaps = 1/133 (0%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAI-RSTCE 486 ++ + + +G++ +L GH ++ I IS+R+ ++ + S D+ + WDL R + R Sbjct: 137 TIRVWDLATGKLKVTLQGHIMTVRDICISARHPYMFSASQDKLVKCWDLERNTVVRDFHG 196 Query: 485 HDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIV 306 GV + S + S D +VR+WD S T +GHR + + IV Sbjct: 197 TLSGVHSVDLHPSLDLIVSAGRDSVVRVWDIRSRSCVLTLAGHRGPINKVRCLPVDPQIV 256 Query: 305 SVSTDKSARVFDI 267 S STD + +++D+ Sbjct: 257 SCSTDATVKLWDL 269
>GBB2_BOVIN (P11017) Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta| subunit 2 (Transducin beta chain 2) (G protein beta 2 subunit) (Fragment) Length = 326 Score = 58.2 bits (139), Expect = 2e-08 Identities = 35/134 (26%), Positives = 61/134 (45%), Gaps = 3/134 (2%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCEH 483 S+ + + + +GH + I + TGS D T ++DL H Sbjct: 193 SIKLWDVRDSMCRQTFIGHESDINAVAFFPNGYAFTTGSDDATCRLFDLRADQELLMYSH 252 Query: 482 DE---GVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNS 312 D G+T +A+ S R + +G D IWD++ GD A +GH + V L V+ DG + Sbjct: 253 DNIICGITSVAFSRSGRLLLAGYDDFNCNIWDAMKGDRAGVLAGHDNRVSCLGVTDDGMA 312 Query: 311 IVSVSTDKSARVFD 270 + + S D ++++ Sbjct: 313 VATGSWDSFLKIWN 326 Score = 55.5 bits (132), Expect = 1e-07 Identities = 37/135 (27%), Positives = 58/135 (42%), Gaps = 3/135 (2%) Frame = -2 Query: 662 SVHIVSINSGQVVGS--LVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLAR-QAIRST 492 S++ + G V S L GHT + C N + T S D T +WD+ Q Sbjct: 108 SIYSLKTREGNVRVSRELPGHTGYLSCCRFLDD-NQIITSSGDTTCALWDIETGQQTVGF 166 Query: 491 CEHDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNS 312 H V L+ R SG D +++WD +TF GH + ++A +G + Sbjct: 167 AGHSGDVMSLSLAPDGRTFVSGACDASIKLWDVRDSMCRQTFIGHESDINAVAFFPNGYA 226 Query: 311 IVSVSTDKSARVFDI 267 + S D + R+FD+ Sbjct: 227 FTTGSDDATCRLFDL 241 Score = 35.4 bits (80), Expect = 0.15 Identities = 37/164 (22%), Positives = 59/164 (35%), Gaps = 46/164 (28%) Frame = -2 Query: 620 SLVGHTNSIECIGISSRYNWVATGSIDRTLIIWD-LARQAIRSTCEHDEGVTCLAWLGSS 444 +L GH I + + + + S D LIIWD + + V A+ S Sbjct: 36 TLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSG 95 Query: 443 RYVASGCID------------GMVRI---------------------------------W 399 +VA G +D G VR+ W Sbjct: 96 NFVACGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFLDDNQIITSSGDTTCALW 155 Query: 398 DSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFDI 267 D +G F+GH V SL+++ DG + VS + D S +++D+ Sbjct: 156 DIETGQQTVGFAGHSGDVMSLSLAPDGRTFVSGACDASIKLWDV 199
>GBLP_ARATH (O24456) Guanine nucleotide-binding protein beta subunit-like| protein (WD-40 repeat auxin-dependent protein ARCA) Length = 327 Score = 57.8 bits (138), Expect = 3e-08 Identities = 35/125 (28%), Positives = 60/125 (48%), Gaps = 7/125 (5%) Frame = -2 Query: 623 GSLVGHTNSIECIGIS-SRYNWVATGSIDRTLIIWDLARQ------AIRSTCEHDEGVTC 465 G++ HT+ + I + + + S D+++I+W L + A R H V Sbjct: 9 GTMRAHTDMVTAIATPIDNADIIVSASRDKSIILWKLTKDDKAYGVAQRRLTGHSHFVED 68 Query: 464 LAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKS 285 + ++ SG DG +R+WD +G R F GH V S+A S D IVS S D++ Sbjct: 69 VVLSSDGQFALSGSWDGELRLWDLAAGVSTRRFVGHTKDVLSVAFSLDNRQIVSASRDRT 128 Query: 284 ARVFD 270 ++++ Sbjct: 129 IKLWN 133 Score = 56.2 bits (134), Expect = 8e-08 Identities = 41/128 (32%), Positives = 69/128 (53%), Gaps = 7/128 (5%) Frame = -2 Query: 617 LVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQ-AIRSTCEHDEGVTCLAWLGSSR 441 L GH++ +E + +SS + +GS D L +WDLA + R H + V +A+ +R Sbjct: 59 LTGHSHFVEDVVLSSDGQFALSGSWDGELRLWDLAAGVSTRRFVGHTKDVLSVAFSLDNR 118 Query: 440 YVASGCIDGMVRIWDSLSGDLARTFS----GHRDVVQSLAVSADG--NSIVSVSTDKSAR 279 + S D +++W++L G+ T S GHRD V + S + +IVS S DK+ + Sbjct: 119 QIVSASRDRTIKLWNTL-GECKYTISEGGEGHRDWVSCVRFSPNTLQPTIVSASWDKTVK 177 Query: 278 VFDISMFK 255 V+++S K Sbjct: 178 VWNLSNCK 185 Score = 50.4 bits (119), Expect = 5e-06 Identities = 32/123 (26%), Positives = 59/123 (47%), Gaps = 6/123 (4%) Frame = -2 Query: 614 VGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCEHDEG----VTCLAWLGS 447 VGHT + + S + + S DRT+ +W+ + + E EG V+C+ + + Sbjct: 102 VGHTKDVLSVAFSLDNRQIVSASRDRTIKLWNTLGECKYTISEGGEGHRDWVSCVRFSPN 161 Query: 446 SRY--VASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVF 273 + + S D V++W+ + L T +GH V ++AVS DG+ S D ++ Sbjct: 162 TLQPTIVSASWDKTVKVWNLSNCKLRSTLAGHTGYVSTVAVSPDGSLCASGGKDGVVLLW 221 Query: 272 DIS 264 D++ Sbjct: 222 DLA 224 Score = 42.4 bits (98), Expect = 0.001 Identities = 36/154 (23%), Positives = 69/154 (44%), Gaps = 19/154 (12%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCEH 483 +V + ++++ ++ +L GHT + + +S + A+G D +++WDLA + E Sbjct: 175 TVKVWNLSNCKLRSTLAGHTGYVSTVAVSPDGSLCASGGKDGVVLLWDLAEGKKLYSLEA 234 Query: 482 DEGVTCLAWLGSSRYVASGCIDGMVRIWDSLS-----------------GDLARTFSGHR 354 + + L + +RY + ++IWD S D + + R Sbjct: 235 NSVIHALCF-SPNRYWLCAATEHGIKIWDLESKSIVEDLKVDLKAEAEKADNSGPAATKR 293 Query: 353 DVV--QSLAVSADGNSIVSVSTDKSARVFDISMF 258 V+ SL SADG+++ S TD RV+ I + Sbjct: 294 KVIYCTSLNWSADGSTLFSGYTDGVIRVWGIGRY 327 Score = 33.5 bits (75), Expect = 0.58 Identities = 21/80 (26%), Positives = 39/80 (48%), Gaps = 6/80 (7%) Frame = -2 Query: 485 HDEGVTCLAW-LGSSRYVASGCIDGMVRIW-----DSLSGDLARTFSGHRDVVQSLAVSA 324 H + VT +A + ++ + S D + +W D G R +GH V+ + +S+ Sbjct: 14 HTDMVTAIATPIDNADIIVSASRDKSIILWKLTKDDKAYGVAQRRLTGHSHFVEDVVLSS 73 Query: 323 DGNSIVSVSTDKSARVFDIS 264 DG +S S D R++D++ Sbjct: 74 DGQFALSGSWDGELRLWDLA 93
>PWP2_MOUSE (Q8BU03) Periodic tryptophan protein 2 homolog| Length = 919 Score = 57.8 bits (138), Expect = 3e-08 Identities = 33/136 (24%), Positives = 66/136 (48%), Gaps = 2/136 (1%) Frame = -2 Query: 656 HIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDR-TLIIWDLARQA-IRSTCEH 483 H+ + ++ SL + + I+S +W+A G L++W+ ++ + H Sbjct: 313 HLHELPEFNLIHSLSISDQRVASVAINSSGDWIAFGCSGMGQLLVWEWQSESYVLKQQGH 372 Query: 482 DEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVS 303 + LA+ +Y+ +G DG V++W++LSG T + H V + + G+ IV+ Sbjct: 373 FNSMVALAYSPDGQYIVTGGDDGKVKVWNTLSGFCFVTLTEHSSGVTGVTFTTTGHVIVT 432 Query: 302 VSTDKSARVFDISMFK 255 S D + R FD+ ++ Sbjct: 433 SSLDGTVRAFDLHRYR 448 Score = 45.1 bits (105), Expect = 2e-04 Identities = 33/127 (25%), Positives = 61/127 (48%), Gaps = 3/127 (2%) Frame = -2 Query: 638 SGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLAR-QAIRS-TCEHDEGVTC 465 SG +L H++ + + ++ + + T S+D T+ +DL R + R+ T +C Sbjct: 404 SGFCFVTLTEHSSGVTGVTFTTTGHVIVTSSLDGTVRAFDLHRYRNFRTFTSPRPTQFSC 463 Query: 464 LAWLGSSRYVASGCIDGM-VRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDK 288 +A S V++G D + +W +G L SGH V L + + + S S DK Sbjct: 464 VAVDSSGEIVSAGAQDSFEIFVWSMQTGRLLDVLSGHEGPVSGLCFNPMKSILASASWDK 523 Query: 287 SARVFDI 267 + R++D+ Sbjct: 524 TVRLWDM 530 Score = 30.8 bits (68), Expect = 3.8 Identities = 25/152 (16%), Positives = 58/152 (38%), Gaps = 21/152 (13%) Frame = -2 Query: 659 VHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQ-AIRSTCEH 483 + + S+ +G+++ L GH + + + + +A+ S D+T+ +WD+ + T Sbjct: 483 IFVWSMQTGRLLDVLSGHEGPVSGLCFNPMKSILASASWDKTVRLWDMFDSWRTKETLTL 542 Query: 482 DEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDV--------------- 348 + + +A ++ + WD + + G D+ Sbjct: 543 TSDALAVTFRPDGAELAVATLNSQITFWDPENAVQVGSIEGRHDLKTGRKELDKITAKHS 602 Query: 347 -----VQSLAVSADGNSIVSVSTDKSARVFDI 267 +L SADG SI++ K ++ + Sbjct: 603 AKGKAFTTLCYSADGQSILAGGMSKFVCLYHV 634
>GBB1_HOMAM (O45040) Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta| subunit 1 (Transducin beta chain 1) Length = 340 Score = 57.4 bits (137), Expect = 4e-08 Identities = 38/135 (28%), Positives = 59/135 (43%), Gaps = 3/135 (2%) Frame = -2 Query: 662 SVHIVSINSGQVVGS--LVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLAR-QAIRST 492 S++ + G V S L GHT + C N + T S D T +WD+ Q Sbjct: 122 SIYSLKTREGNVRVSRELPGHTGYLSCCRFVDD-NQIVTSSGDMTCALWDIETGQQCTQF 180 Query: 491 CEHDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNS 312 H V L+ + R SG D ++WD G +TF GH + ++ +G++ Sbjct: 181 TGHTGDVMSLSLSPNMRTFTSGACDASAKLWDIRDGMCRQTFPGHESDINAVTFFPNGHA 240 Query: 311 IVSVSTDKSARVFDI 267 + S D + R+FDI Sbjct: 241 FATGSDDATCRLFDI 255 Score = 55.1 bits (131), Expect = 2e-07 Identities = 34/134 (25%), Positives = 62/134 (46%), Gaps = 3/134 (2%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCEH 483 S + I G + GH + I + + ATGS D T ++D+ + H Sbjct: 207 SAKLWDIRDGMCRQTFPGHESDINAVTFFPNGHAFATGSDDATCRLFDIRADQELAMYSH 266 Query: 482 DE---GVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNS 312 D G+T +A+ S + + +G D +WDS+ + A +GH + V L V+ DG + Sbjct: 267 DNIICGITSVAFSKSGKLLLAGYDDFNCNVWDSMRTERAGVLAGHDNRVSCLGVTEDGMA 326 Query: 311 IVSVSTDKSARVFD 270 + + S D ++++ Sbjct: 327 VATGSWDSFLKIWN 340 Score = 35.4 bits (80), Expect = 0.15 Identities = 32/123 (26%), Positives = 52/123 (42%), Gaps = 5/123 (4%) Frame = -2 Query: 620 SLVGHTNSIECIGISSRYNWVATGSIDRTLIIWD-LARQAIRSTCEHDEGVTCLAWLGSS 444 +L GH I + S + + S D LI+WD + + V A+ S Sbjct: 50 TLRGHLAKIYAMHWGSDSRNLVSASQDGKLIVWDSYTTNKVHAIPLRSSWVMTCAYAPSG 109 Query: 443 RYVASGCIDGMVRIWDSLSGD----LARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARV 276 YVA G +D + I+ + + ++R GH + S D N IV+ S D + + Sbjct: 110 SYVACGGLDNICSIYSLKTREGNVRVSRELPGHTGYL-SCCRFVDDNQIVTSSGDMTCAL 168 Query: 275 FDI 267 +DI Sbjct: 169 WDI 171
>TEP1_HUMAN (Q99973) Telomerase protein component 1 (Telomerase-associated| protein 1) (Telomerase protein 1) (p240) (p80 telomerase homolog) Length = 2627 Score = 57.4 bits (137), Expect = 4e-08 Identities = 42/122 (34%), Positives = 59/122 (48%), Gaps = 6/122 (4%) Frame = -2 Query: 617 LVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQ----AIRS--TCEHDEGVTCLAW 456 L GH + C S+ +ATG DR+L+ WD+ I S C H + VT AW Sbjct: 2057 LRGHEGPVSCCSFSTDGGSLATGGRDRSLLCWDVRTPKTPVLIHSFPAC-HRDWVTGCAW 2115 Query: 455 LGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARV 276 + ++ DG V +WD SG F GH+ V AV+A +VSVS D + +V Sbjct: 2116 TKDNLLISCSS-DGSVGLWDPESGQRLGQFLGHQSAVS--AVAAVEEHVVSVSRDGTLKV 2172 Query: 275 FD 270 +D Sbjct: 2173 WD 2174 Score = 50.8 bits (120), Expect = 4e-06 Identities = 38/141 (26%), Positives = 63/141 (44%), Gaps = 9/141 (6%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCEH 483 SV + SGQ +G +GH +++ + + V + S D TL +WD + S H Sbjct: 2129 SVGLWDPESGQRLGQFLGHQSAVSAVAAVEEH--VVSVSRDGTLKVWDHQGVELTSIPAH 2186 Query: 482 DEGVT-CLAWL--------GSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAV 330 ++ C A + GS V + +DG R+W L T GH V++ AV Sbjct: 2187 SGPISHCAAAMEPRAAGQPGSELLVVTVGLDGATRLWHPLLVCQTHTLLGHSGPVRAAAV 2246 Query: 329 SADGNSIVSVSTDKSARVFDI 267 S +++ S D S R++ + Sbjct: 2247 SETSGLMLTASEDGSVRLWQV 2267 Score = 35.4 bits (80), Expect = 0.15 Identities = 21/90 (23%), Positives = 36/90 (40%), Gaps = 2/90 (2%) Frame = -2 Query: 620 SLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTC--EHDEGVTCLAWLGS 447 +L+GH+ + +S + T S D ++ +W + ++A TC VT +AW Sbjct: 2233 TLLGHSGPVRAAAVSETSGLMLTASEDGSVRLWQVPKEA-DDTCIPRSSAAVTAVAWAPD 2291 Query: 446 SRYVASGCIDGMVRIWDSLSGDLARTFSGH 357 SG G + +W GH Sbjct: 2292 GSMAVSGNQAGELILWQEAKAVATAQAPGH 2321
>PRL2_ARATH (Q39190) PP1/PP2A phosphatases pleiotropic regulator PRL2| Length = 479 Score = 57.4 bits (137), Expect = 4e-08 Identities = 36/118 (30%), Positives = 53/118 (44%), Gaps = 1/118 (0%) Frame = -2 Query: 617 LVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCE-HDEGVTCLAWLGSSR 441 L GH + + W TGS DRT+ IWD+A ++ T H V LA Sbjct: 166 LQGHLGWVRSVAFDPSNEWFCTGSADRTIKIWDVATGVLKLTLTGHIGQVRGLAVSNRHT 225 Query: 440 YVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFDI 267 Y+ S D V+ WD + R++ GH V LA+ + +++ D RV+DI Sbjct: 226 YMFSAGDDKQVKCWDLEQNKVIRSYHGHLHGVYCLALHPTLDVVLTGGRDSVCRVWDI 283 Score = 55.5 bits (132), Expect = 1e-07 Identities = 29/118 (24%), Positives = 51/118 (43%) Frame = -2 Query: 644 INSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCEHDEGVTC 465 + +V+ S GH + + C+ + + V TG D +WD+ + HD V Sbjct: 241 LEQNKVIRSYHGHLHGVYCLALHPTLDVVLTGGRDSVCRVWDIRTKMQIFVLPHDSDVFS 300 Query: 464 LAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTD 291 + + V +G D ++ WD G T + H+ V+++A+ N VS S D Sbjct: 301 VLARPTDPQVITGSHDSTIKFWDLRYGKSMATITNHKKTVRAMALHPKENDFVSASAD 358 Score = 50.1 bits (118), Expect = 6e-06 Identities = 34/133 (25%), Positives = 64/133 (48%), Gaps = 1/133 (0%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLAR-QAIRSTCE 486 ++ I + +G + +L GH + + +S+R+ ++ + D+ + WDL + + IRS Sbjct: 193 TIKIWDVATGVLKLTLTGHIGQVRGLAVSNRHTYMFSAGDDKQVKCWDLEQNKVIRSYHG 252 Query: 485 HDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIV 306 H GV CLA + V +G D + R+WD + DV LA D ++ Sbjct: 253 HLHGVYCLALHPTLDVVLTGGRDSVCRVWDIRTKMQIFVLPHDSDVFSVLARPTD-PQVI 311 Query: 305 SVSTDKSARVFDI 267 + S D + + +D+ Sbjct: 312 TGSHDSTIKFWDL 324 Score = 42.0 bits (97), Expect = 0.002 Identities = 23/73 (31%), Positives = 37/73 (50%) Frame = -2 Query: 473 VTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVST 294 V +A+ S+ + +G D ++IWD +G L T +GH V+ LAVS + S Sbjct: 173 VRSVAFDPSNEWFCTGSADRTIKIWDVATGVLKLTLTGHIGQVRGLAVSNRHTYMFSAGD 232 Query: 293 DKSARVFDISMFK 255 DK + +D+ K Sbjct: 233 DKQVKCWDLEQNK 245
>GBB4_MOUSE (P29387) Guanine nucleotide-binding protein beta subunit 4| (Transducin beta chain 4) Length = 339 Score = 57.4 bits (137), Expect = 4e-08 Identities = 37/128 (28%), Positives = 58/128 (45%), Gaps = 3/128 (2%) Frame = -2 Query: 644 INSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCEHDE---G 474 I G S GH + I + ATGS D T ++DL HD G Sbjct: 212 IRDGMCRQSFTGHISDINAVSFFPSGYAFATGSDDATCRLFDLRADQELLLYSHDNIICG 271 Query: 473 VTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVST 294 +T +A+ S R + +G D +WD+L G + +GH + V L V+ DG ++ + S Sbjct: 272 ITSVAFSKSGRLLLAGYDDFNCSVWDALKGGRSGVLAGHDNRVSCLGVTDDGMAVATGSW 331 Query: 293 DKSARVFD 270 D R+++ Sbjct: 332 DSFLRIWN 339 Score = 48.5 bits (114), Expect = 2e-05 Identities = 31/123 (25%), Positives = 53/123 (43%), Gaps = 1/123 (0%) Frame = -2 Query: 632 QVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLAR-QAIRSTCEHDEGVTCLAW 456 +V L GHT + C + T S D T +WD+ Q + H V L+ Sbjct: 133 RVSRELPGHTGYLSCCRFLDD-GQIITSSGDTTCALWDIETGQQTTTFTGHSGDVMSLSL 191 Query: 455 LGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARV 276 + SG D ++WD G ++F+GH + +++ G + + S D + R+ Sbjct: 192 SPDLKTFVSGACDASSKLWDIRDGMCRQSFTGHISDINAVSFFPSGYAFATGSDDATCRL 251 Query: 275 FDI 267 FD+ Sbjct: 252 FDL 254 Score = 47.8 bits (112), Expect = 3e-05 Identities = 32/105 (30%), Positives = 55/105 (52%), Gaps = 5/105 (4%) Frame = -2 Query: 566 NWVATGSIDRTLIIWDLARQA--IRSTCE---HDEGVTCLAWLGSSRYVASGCIDGMVRI 402 N+VA G +D I++L + +R + E H ++C +L + + S D + Sbjct: 109 NYVACGGLDNICSIYNLKTREGNVRVSRELPGHTGYLSCCRFLDDGQIITSSG-DTTCAL 167 Query: 401 WDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFDI 267 WD +G TF+GH V SL++S D + VS + D S++++DI Sbjct: 168 WDIETGQQTTTFTGHSGDVMSLSLSPDLKTFVSGACDASSKLWDI 212
>COPB2_DROME (O62621) Coatomer subunit beta' (Beta'-coat protein) (Beta'-COP)| Length = 914 Score = 57.0 bits (136), Expect = 5e-08 Identities = 34/125 (27%), Positives = 63/125 (50%), Gaps = 4/125 (3%) Frame = -2 Query: 611 GHTNSIECIGISSR-YNWVATGSIDRTLIIWDLARQAIRSTCE-HDEGVTCLAWL--GSS 444 GHT+ + I + + N A+ S+DRT+ +W L T E H++GV C+ + G Sbjct: 140 GHTHYVMQIVFNPKDNNTFASASLDRTVKVWQLGSNFANFTLEGHEKGVNCVDYYHGGDK 199 Query: 443 RYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFDIS 264 Y+ SG D +V+IWD + +T GH + ++ + +++ S D + R++ Sbjct: 200 PYLISGADDRLVKIWDYQNKTCVQTLEGHAQNISAVCFHPELPIVLTGSEDGTVRIWHSG 259 Query: 263 MFK*E 249 ++ E Sbjct: 260 TYRLE 264 Score = 45.1 bits (105), Expect = 2e-04 Identities = 30/134 (22%), Positives = 61/134 (45%), Gaps = 3/134 (2%) Frame = -2 Query: 659 VHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDL-ARQAIRSTCEH 483 VHI++ + Q+V + +R NW+ TGS D + +++ + + S H Sbjct: 39 VHIMNYENQQMVKDFEVCDVPVRSARFVARKNWILTGSDDMQIRVFNYNTLEKVHSFEAH 98 Query: 482 DEGVTCLAWLGSSRYVASGCIDGMVRIWD-SLSGDLARTFSGHRDVVQSLAVS-ADGNSI 309 + + C+A + V + D ++++W+ R F GH V + + D N+ Sbjct: 99 SDYLRCIAVHPTQPLVLTSSDDMLIKLWNWEKMWACQRVFEGHTHYVMQIVFNPKDNNTF 158 Query: 308 VSVSTDKSARVFDI 267 S S D++ +V+ + Sbjct: 159 ASASLDRTVKVWQL 172
>GBLP_BRANA (Q39336) Guanine nucleotide-binding protein beta subunit-like| protein Length = 327 Score = 56.6 bits (135), Expect = 6e-08 Identities = 41/128 (32%), Positives = 69/128 (53%), Gaps = 7/128 (5%) Frame = -2 Query: 617 LVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQ-AIRSTCEHDEGVTCLAWLGSSR 441 L GH++ +E + +SS + +GS D L +WDLA + R H + V +A+ +R Sbjct: 59 LTGHSHFVEDVVLSSDGQFALSGSWDGELRLWDLAAGVSTRRFVGHTKDVLSVAFSLDNR 118 Query: 440 YVASGCIDGMVRIWDSLSGDLARTFS----GHRDVVQSLAVSADG--NSIVSVSTDKSAR 279 + S D +++W++L G+ T S GHRD V + S + +IVS S DK+ + Sbjct: 119 QIVSASRDRTIKLWNTL-GECKYTISEGGEGHRDWVSCVRFSPNTLQPTIVSASCDKTVK 177 Query: 278 VFDISMFK 255 V+++S K Sbjct: 178 VWNLSNCK 185 Score = 56.6 bits (135), Expect = 6e-08 Identities = 34/125 (27%), Positives = 59/125 (47%), Gaps = 7/125 (5%) Frame = -2 Query: 623 GSLVGHTNSIECIGIS-SRYNWVATGSIDRTLIIWDLARQ------AIRSTCEHDEGVTC 465 G++ HT+ + I + + + S D+++I+W L + R H V Sbjct: 9 GTMRAHTDMVTAIATPIDNSDTIVSASRDKSIIVWKLTKDDKSYGVRQRRLTGHSHFVED 68 Query: 464 LAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKS 285 + ++ SG DG +R+WD +G R F GH V S+A S D IVS S D++ Sbjct: 69 VVLSSDGQFALSGSWDGELRLWDLAAGVSTRRFVGHTKDVLSVAFSLDNRQIVSASRDRT 128 Query: 284 ARVFD 270 ++++ Sbjct: 129 IKLWN 133 Score = 51.2 bits (121), Expect = 3e-06 Identities = 32/123 (26%), Positives = 59/123 (47%), Gaps = 6/123 (4%) Frame = -2 Query: 614 VGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCEHDEG----VTCLAWLGS 447 VGHT + + S + + S DRT+ +W+ + + E EG V+C+ + + Sbjct: 102 VGHTKDVLSVAFSLDNRQIVSASRDRTIKLWNTLGECKYTISEGGEGHRDWVSCVRFSPN 161 Query: 446 SRY--VASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVF 273 + + S D V++W+ + L T +GH V ++AVS DG+ S D ++ Sbjct: 162 TLQPTIVSASCDKTVKVWNLSNCKLRSTLAGHTGYVSTVAVSPDGSLCASGGKDGVVLLW 221 Query: 272 DIS 264 D++ Sbjct: 222 DLA 224 Score = 43.9 bits (102), Expect = 4e-04 Identities = 37/154 (24%), Positives = 70/154 (45%), Gaps = 19/154 (12%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCEH 483 +V + ++++ ++ +L GHT + + +S + A+G D +++WDLA + E Sbjct: 175 TVKVWNLSNCKLRSTLAGHTGYVSTVAVSPDGSLCASGGKDGVVLLWDLAEGKKLYSLEA 234 Query: 482 DEGVTCLAWLGSSRYVASGCIDGMVRIWDSLS-----------------GDLARTFSGHR 354 + + L + +RY + ++IWD S D + T + R Sbjct: 235 NSVIHALCFT-PNRYWLCAATEQGIKIWDLESKTVVEDLKVDLKAEAEKSDGSGTAATKR 293 Query: 353 DVV--QSLAVSADGNSIVSVSTDKSARVFDISMF 258 V+ SL SADG+++ S TD RV+ I + Sbjct: 294 KVIYCTSLNWSADGSTLFSGYTDGVIRVWGIGRY 327 Score = 33.9 bits (76), Expect = 0.45 Identities = 22/80 (27%), Positives = 39/80 (48%), Gaps = 6/80 (7%) Frame = -2 Query: 485 HDEGVTCLAW-LGSSRYVASGCIDGMVRIW-----DSLSGDLARTFSGHRDVVQSLAVSA 324 H + VT +A + +S + S D + +W D G R +GH V+ + +S+ Sbjct: 14 HTDMVTAIATPIDNSDTIVSASRDKSIIVWKLTKDDKSYGVRQRRLTGHSHFVEDVVLSS 73 Query: 323 DGNSIVSVSTDKSARVFDIS 264 DG +S S D R++D++ Sbjct: 74 DGQFALSGSWDGELRLWDLA 93
>GBB3_CANFA (P79147) Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta| subunit 3 (Transducin beta chain 3) Length = 340 Score = 56.6 bits (135), Expect = 6e-08 Identities = 40/135 (29%), Positives = 63/135 (46%), Gaps = 4/135 (2%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCEH 483 S + + G + GH + I I + TGS D + ++DL R T Sbjct: 207 SAKLWDVREGTCRQTFTGHESDINAICFFPNGEAICTGSDDASCRLFDL-RADQELTAYS 265 Query: 482 DE----GVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGN 315 DE G+T +A+ S R + +G D IWDS+ G+ SGH + V L V+ADG Sbjct: 266 DESIICGITSVAFSLSGRLLFAGYDDFNCNIWDSMKGERVGILSGHDNRVSCLGVTADGM 325 Query: 314 SIVSVSTDKSARVFD 270 ++ + S D +V++ Sbjct: 326 AVATGSWDSFLKVWN 340 Score = 53.9 bits (128), Expect = 4e-07 Identities = 36/135 (26%), Positives = 58/135 (42%), Gaps = 3/135 (2%) Frame = -2 Query: 662 SVHIVSINSGQVVGS--LVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRST- 492 S++ + G V S L HT + C N + T S D T +WD+ ++ Sbjct: 122 SIYSLKSREGNVKVSRELSAHTGYLSCCRFLDDNN-IVTSSGDTTCALWDIETGQQKTVF 180 Query: 491 CEHDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNS 312 H LA + SG D ++WD G +TF+GH + ++ +G + Sbjct: 181 VGHTGDCMSLAVSPDFKLFISGACDASAKLWDVREGTCRQTFTGHESDINAICFFPNGEA 240 Query: 311 IVSVSTDKSARVFDI 267 I + S D S R+FD+ Sbjct: 241 ICTGSDDASCRLFDL 255 Score = 36.6 bits (83), Expect = 0.069 Identities = 32/123 (26%), Positives = 54/123 (43%), Gaps = 5/123 (4%) Frame = -2 Query: 620 SLVGHTNSIECIGISSRYNWVATGSIDRTLIIWD-LARQAIRSTCEHDEGVTCLAWLGSS 444 +L GH I + ++ + + S D LI+WD + + V A+ S Sbjct: 50 TLRGHLAKIYAMHWATDSKLLVSASQDGKLIVWDTYTTNKVHAIPLRSSWVMTCAYAPSG 109 Query: 443 RYVASGCIDGMVRIWDSLSGD----LARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARV 276 +VA G +D M I+ S + ++R S H + S D N+IV+ S D + + Sbjct: 110 NFVACGGLDNMCSIYSLKSREGNVKVSRELSAHTGYL-SCCRFLDDNNIVTSSGDTTCAL 168 Query: 275 FDI 267 +DI Sbjct: 169 WDI 171
>WDR33_HUMAN (Q9C0J8) WD-repeat protein 33 (WD-repeat protein WDC146)| Length = 1336 Score = 56.6 bits (135), Expect = 6e-08 Identities = 37/123 (30%), Positives = 55/123 (44%), Gaps = 3/123 (2%) Frame = -2 Query: 608 HTNSIECIGISSRYNWVATGSIDRTLIIWDLAR-QAIRSTCEHDEGVTCLAWLGSSRYVA 432 H +I S N AT S D T+ IWD R R H V C+ W + V Sbjct: 201 HKEAIREASFSPTDNKFATCSDDGTVRIWDFLRCHEERILRGHGADVKCVDWHPTKGLVV 260 Query: 431 SGCIDGM--VRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFDISMF 258 SG D ++ WD +G T H++ V + ++ +GN +++ S D ++FDI Sbjct: 261 SGSKDSQQPIKFWDPKTGQSLATLHAHKNTVMEVKLNLNGNWLLTASRDHLCKLFDIRNL 320 Query: 257 K*E 249 K E Sbjct: 321 KEE 323 Score = 39.3 bits (90), Expect = 0.011 Identities = 29/124 (23%), Positives = 58/124 (46%), Gaps = 4/124 (3%) Frame = -2 Query: 638 SGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDL--ARQAIRSTCEHDEGVTC 465 +GQ + +L H N++ + ++ NW+ T S D ++D+ ++ ++ H + T Sbjct: 277 TGQSLATLHAHKNTVMEVKLNLNGNWLLTASRDHLCKLFDIRNLKEELQVFRGHKKEATA 336 Query: 464 LAWLG-SSRYVASGCIDGMVRIWD-SLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTD 291 +AW ASG DG + W + ++ H ++ SLA G+ + S S D Sbjct: 337 VAWHPVHEGLFASGGSDGSLLFWHVGVEKEVGGMEMAHEGMIWSLAWHPLGHILCSGSND 396 Query: 290 KSAR 279 +++ Sbjct: 397 HTSK 400 Score = 31.6 bits (70), Expect = 2.2 Identities = 25/109 (22%), Positives = 40/109 (36%) Frame = -2 Query: 617 LVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCEHDEGVTCLAWLGSSRY 438 L H + + + S W+ T + W ++ H E + ++ + Sbjct: 157 LQAHDSPVRAMTWSHNDMWMLTADHGGYVKYWQSNMNNVKMFQAHKEAIREASFSPTDNK 216 Query: 437 VASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTD 291 A+ DG VRIWD L R GH V+ + +VS S D Sbjct: 217 FATCSDDGTVRIWDFLRCHEERILRGHGADVKCVDWHPTKGLVVSGSKD 265
>NUDF_EMENI (Q00664) Nuclear migration protein nudF| Length = 444 Score = 56.6 bits (135), Expect = 6e-08 Identities = 40/125 (32%), Positives = 68/125 (54%), Gaps = 6/125 (4%) Frame = -2 Query: 620 SLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCE-HDEGVTCLAWLG-- 450 +L H +++ C+ + +A+GS D T+ IWD I T + H GV+ L + G Sbjct: 109 TLTSHRDAVTCVAFHPVFTSLASGSEDCTIKIWDWELGEIERTLKGHIRGVSGLDYGGQK 168 Query: 449 SSRYVASGCIDGMVRIWDSLSGDLA--RTFSGHRDVVQSLA-VSADGNSIVSVSTDKSAR 279 + +AS D +++WD S D A RT SGH V S+ ++++ N ++S S D + R Sbjct: 169 GNTLLASCSSDLTIKLWDP-SKDYANIRTLSGHDHSVSSVRFLTSNDNHLISASRDGTLR 227 Query: 278 VFDIS 264 ++D+S Sbjct: 228 IWDVS 232 Score = 49.3 bits (116), Expect = 1e-05 Identities = 33/123 (26%), Positives = 56/123 (45%), Gaps = 22/123 (17%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGIS---------------------SRYNWVATGS 546 ++ + ++S + +L+GH N IEC + S +VATG+ Sbjct: 268 AITVWEVSSAEPKAALLGHENFIECCVFAPPASYEHLATLAGLKKPPPATSSCEFVATGA 327 Query: 545 IDRTLIIWDLARQAIRSTCEHDEGVTCLAWLGSSRYVASGCIDGMVRIWD-SLSGDLART 369 D+T+ +W+ + I++ HD V L + +Y+ S D +R WD S G L +T Sbjct: 328 RDKTIKLWEARGRLIKTLHGHDNWVRGLVFHPGGKYLFSVSDDKTIRCWDLSQEGRLVKT 387 Query: 368 FSG 360 SG Sbjct: 388 ISG 390 Score = 48.1 bits (113), Expect = 2e-05 Identities = 35/156 (22%), Positives = 69/156 (44%), Gaps = 23/156 (14%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNS-IECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTC- 489 ++ I +++G V + T S I + S W+ +G D+ + +W+++ ++ Sbjct: 225 TLRIWDVSTGFCVKVIKSATESWIRDVSPSFDGKWLVSGGRDQAITVWEVSSAEPKAALL 284 Query: 488 EHDEGVTCLAWL---------------------GSSRYVASGCIDGMVRIWDSLSGDLAR 372 H+ + C + S +VA+G D +++W++ G L + Sbjct: 285 GHENFIECCVFAPPASYEHLATLAGLKKPPPATSSCEFVATGARDKTIKLWEA-RGRLIK 343 Query: 371 TFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFDIS 264 T GH + V+ L G + SVS DK+ R +D+S Sbjct: 344 TLHGHDNWVRGLVFHPGGKYLFSVSDDKTIRCWDLS 379
>PRP46_CANAL (Q5A7Q3) Pre-mRNA-splicing factor PRP46 (Pre-mRNA-processing| protein 46) Length = 389 Score = 56.6 bits (135), Expect = 6e-08 Identities = 40/144 (27%), Positives = 66/144 (45%), Gaps = 6/144 (4%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQ------AI 501 ++ I + + L GH I + IS R+ ++ +G D++L WDL R I Sbjct: 109 TIKIWDFENNSLKAVLTGHVLGIRSLCISKRHPYLFSGGEDKSLRCWDLERSNSDAGCQI 168 Query: 500 RSTCEHDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSAD 321 RS H GV + + SG D +VR+WD S A T GH + + S+ + Sbjct: 169 RSYHGHLGGVYSIGLHPELDVLFSGGKDCVVRVWDIRSRVEAMTLLGHTNDITSIETDYN 228 Query: 320 GNSIVSVSTDKSARVFDISMFK*E 249 +++ S D + R++D+ K E Sbjct: 229 DPQVITSSMDGTIRLWDLRKSKTE 252 Score = 48.1 bits (113), Expect = 2e-05 Identities = 36/121 (29%), Positives = 54/121 (44%), Gaps = 7/121 (5%) Frame = -2 Query: 608 HTNSIECIGISSRYN-WVATGSIDRTLIIWDLARQAIRSTCE-HDEGVTCLAWLGSSRYV 435 H I I + N W TGS D T+ IWD ++++ H G+ L Y+ Sbjct: 84 HQGWIRAIALDEITNKWYVTGSADSTIKIWDFENNSLKAVLTGHVLGIRSLCISKRHPYL 143 Query: 434 ASGCIDGMVRIWD-----SLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFD 270 SG D +R WD S +G R++ GH V S+ + + + + S D RV+D Sbjct: 144 FSGGEDKSLRCWDLERSNSDAGCQIRSYHGHLGGVYSIGLHPELDVLFSGGKDCVVRVWD 203 Query: 269 I 267 I Sbjct: 204 I 204 Score = 37.7 bits (86), Expect = 0.031 Identities = 21/103 (20%), Positives = 45/103 (43%), Gaps = 1/103 (0%) Frame = -2 Query: 641 NSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDL-ARQAIRSTCEHDEGVTC 465 ++G + S GH + IG+ + + +G D + +WD+ +R + H +T Sbjct: 163 DAGCQIRSYHGHLGGVYSIGLHPELDVLFSGGKDCVVRVWDIRSRVEAMTLLGHTNDITS 222 Query: 464 LAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSL 336 + + V + +DG +R+WD + H ++S+ Sbjct: 223 IETDYNDPQVITSSMDGTIRLWDLRKSKTELLITNHSKSIRSM 265
>U3IP2_MOUSE (Q91WM3) U3 small nucleolar RNA-interacting protein 2 (U3 small| nucleolar ribonucleoproptein-associated 55-kDa protein) (U3 snoRNP-associated 55-kDa protein) (U3-55K) Length = 475 Score = 56.2 bits (134), Expect = 8e-08 Identities = 37/128 (28%), Positives = 59/128 (46%), Gaps = 12/128 (9%) Frame = -2 Query: 617 LVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLA------------RQAIRSTCEHDEG 474 L GH SI C+ I+ + + + D T+I W + + A H Sbjct: 142 LRGHQLSITCLVITPDDLAIFSAAKDCTIIKWSVETGRKLHVIPRAKKGAQGQPAGHSSH 201 Query: 473 VTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVST 294 V C+A +Y+ASG ++ IW++ S TF+GHRD V LA + + S S Sbjct: 202 VLCMAISSDGKYLASGDRSKLILIWEAQSCQHLYTFTGHRDAVSGLAFRKGTHQLYSTSH 261 Query: 293 DKSARVFD 270 D+S +V++ Sbjct: 262 DRSVKVWN 269 Score = 54.3 bits (129), Expect = 3e-07 Identities = 31/132 (23%), Positives = 63/132 (47%), Gaps = 1/132 (0%) Frame = -2 Query: 659 VHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLAR-QAIRSTCEH 483 +H++ G GH++ + C+ ISS ++A+G + ++IW+ Q + + H Sbjct: 181 LHVIPRAKKGAQGQPAGHSSHVLCMAISSDGKYLASGDRSKLILIWEAQSCQHLYTFTGH 240 Query: 482 DEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVS 303 + V+ LA+ + + S D V++W++ T GH+D V +L + + + Sbjct: 241 RDAVSGLAFRKGTHQLYSTSHDRSVKVWNAAENSYVETLFGHQDAVAALDALSRECCVTA 300 Query: 302 VSTDKSARVFDI 267 D + RV+ I Sbjct: 301 GGRDGTVRVWKI 312 Score = 38.5 bits (88), Expect = 0.018 Identities = 22/88 (25%), Positives = 40/88 (45%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCEH 483 SV + + V +L GH +++ + SR V G D T+ +W + ++ H Sbjct: 264 SVKVWNAAENSYVETLFGHQDAVAALDALSRECCVTAGGRDGTVRVWKIPEESQLVFYGH 323 Query: 482 DEGVTCLAWLGSSRYVASGCIDGMVRIW 399 + C+ L + ++ SG DG V +W Sbjct: 324 QGSIDCI-HLINEEHMVSGADDGSVALW 350
>U3IP2_HUMAN (O43818) U3 small nucleolar RNA-interacting protein 2 (U3 small| nucleolar ribonucleoproptein-associated 55-kDa protein) (U3 snoRNP-associated 55-kDa protein) (U3-55K) Length = 475 Score = 56.2 bits (134), Expect = 8e-08 Identities = 35/130 (26%), Positives = 62/130 (47%), Gaps = 12/130 (9%) Frame = -2 Query: 617 LVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLA------------RQAIRSTCEHDEG 474 L GH SI C+ ++ + + + + D ++I W + + A H Sbjct: 142 LRGHQLSITCLVVTPDDSAIFSAAKDCSIIKWSVESGRKLHVIPRAKKGAEGKPPGHSSH 201 Query: 473 VTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVST 294 V C+A +Y+ASG ++ IW++ S TF+GHRD V LA + + S S Sbjct: 202 VLCMAISSDGKYLASGDRSKLILIWEAQSCQHLYTFTGHRDAVSGLAFRRGTHQLYSTSH 261 Query: 293 DKSARVFDIS 264 D+S +V++++ Sbjct: 262 DRSVKVWNVA 271 Score = 52.4 bits (124), Expect = 1e-06 Identities = 31/132 (23%), Positives = 62/132 (46%), Gaps = 1/132 (0%) Frame = -2 Query: 659 VHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLAR-QAIRSTCEH 483 +H++ G GH++ + C+ ISS ++A+G + ++IW+ Q + + H Sbjct: 181 LHVIPRAKKGAEGKPPGHSSHVLCMAISSDGKYLASGDRSKLILIWEAQSCQHLYTFTGH 240 Query: 482 DEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVS 303 + V+ LA+ + + S D V++W+ T GH+D V +L + + + Sbjct: 241 RDAVSGLAFRRGTHQLYSTSHDRSVKVWNVAENSYVETLFGHQDAVAALDALSRECCVTA 300 Query: 302 VSTDKSARVFDI 267 D + RV+ I Sbjct: 301 GGRDGTVRVWKI 312 Score = 40.0 bits (92), Expect = 0.006 Identities = 22/88 (25%), Positives = 41/88 (46%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCEH 483 SV + ++ V +L GH +++ + SR V G D T+ +W + ++ H Sbjct: 264 SVKVWNVAENSYVETLFGHQDAVAALDALSRECCVTAGGRDGTVRVWKIPEESQLVFYGH 323 Query: 482 DEGVTCLAWLGSSRYVASGCIDGMVRIW 399 + C+ L + ++ SG DG V +W Sbjct: 324 QGSIDCI-HLINEEHMVSGADDGSVALW 350
>POF1_SCHPO (P87053) F-box/WD-repeat protein pof1 (Skp1-binding protein 1)| Length = 605 Score = 56.2 bits (134), Expect = 8e-08 Identities = 37/119 (31%), Positives = 62/119 (52%), Gaps = 1/119 (0%) Frame = -2 Query: 617 LVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLAR-QAIRSTCEHDEGVTCLAWLGSSR 441 L GH++ + C+ + N +A+GS D T+ +W+LA Q + H GVTCL + Sbjct: 269 LSGHSDGVMCLQLVR--NILASGSYDATIRLWNLATFQQVALLEGHSSGVTCLQF--DQC 324 Query: 440 YVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFDIS 264 + SG +D +RIW+ + + GH D V L ++ D +VS S D + +++ S Sbjct: 325 KLISGSMDKTIRIWNYRTSECISILHGHTDSV--LCLTFDSTLLVSGSADCTVKLWHFS 381 Score = 50.8 bits (120), Expect = 4e-06 Identities = 36/136 (26%), Positives = 63/136 (46%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCEH 483 ++ I + + + + L GHT+S+ C+ S + +GS D T+ +W + + H Sbjct: 334 TIRIWNYRTSECISILHGHTDSVLCLTFDSTL--LVSGSADCTVKLWHFSGGKRITLRGH 391 Query: 482 DEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVS 303 V + + V SG D ++IW + TFS H VQSLA++ + + S Sbjct: 392 TGPVNSVRIIRDRGLVLSGSDDSTIKIWSLETNTCLHTFSAHIGPVQSLALA--DSRLFS 449 Query: 302 VSTDKSARVFDISMFK 255 S D + + +DI K Sbjct: 450 CSLDGTIKQWDIEKKK 465 Score = 40.8 bits (94), Expect = 0.004 Identities = 33/117 (28%), Positives = 50/117 (42%) Frame = -2 Query: 620 SLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCEHDEGVTCLAWLGSSR 441 +L GHT + + I V +GS D T+ IW L T G L SR Sbjct: 387 TLRGHTGPVNSVRIIRDRGLVLSGSDDSTIKIWSLETNTCLHTFSAHIGPVQSLALADSR 446 Query: 440 YVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFD 270 + S +DG ++ WD T GH + V +A AD ++S + D +V++ Sbjct: 447 -LFSCSLDGTIKQWDIEKKKCVHTLFGHIEGVWEIA--ADHLRLISGAHDGVVKVWE 500 Score = 35.4 bits (80), Expect = 0.15 Identities = 24/112 (21%), Positives = 56/112 (50%), Gaps = 1/112 (0%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQ-AIRSTCE 486 ++ I S+ + + + H ++ + ++ + + + S+D T+ WD+ ++ + + Sbjct: 415 TIKIWSLETNTCLHTFSAHIGPVQSLALAD--SRLFSCSLDGTIKQWDIEKKKCVHTLFG 472 Query: 485 HDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAV 330 H EGV +A + SG DG+V++W++ + T H + V S+A+ Sbjct: 473 HIEGVWEIA--ADHLRLISGAHDGVVKVWEAC--ECVHTLKNHSEPVTSVAL 520
>WS17_SCHMA (Q26544) WD-repeat protein SL1-17| Length = 301 Score = 56.2 bits (134), Expect = 8e-08 Identities = 37/131 (28%), Positives = 61/131 (46%), Gaps = 2/131 (1%) Frame = -2 Query: 659 VHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDL--ARQAIRSTCE 486 V I + +G V L GH + + S +A+ S D+ + ++D+ R I S Sbjct: 169 VSICDLETGSVQ-FLDGHATPVRSVSFSPDGRLLASASDDKQIKVFDVRDGRLVIPSLNG 227 Query: 485 HDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIV 306 H V + + +R++ + D VRIWD S + F+ H D V S GN+I+ Sbjct: 228 HKGWVVSVDFASDNRHLVTASTDCSVRIWDLASKEEKHCFNTHEDQVWCARYSPQGNNII 287 Query: 305 SVSTDKSARVF 273 SV D+S ++ Sbjct: 288 SVGDDRSIMIY 298 Score = 50.1 bits (118), Expect = 6e-06 Identities = 32/133 (24%), Positives = 69/133 (51%), Gaps = 1/133 (0%) Frame = -2 Query: 659 VHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCEHD 480 V+++++ + Q GS+ + + S + +A G+I+ + I DL +++ H Sbjct: 127 VNMINVQTAQKEGSIQLEGKFVYXLAYISDGSKLAAGTINGLVSICDLETGSVQFLDGHA 186 Query: 479 EGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLA-RTFSGHRDVVQSLAVSADGNSIVS 303 V +++ R +AS D ++++D G L + +GH+ V S+ ++D +V+ Sbjct: 187 TPVRSVSFSPDGRLLASASDDKQIKVFDVRDGRLVIPSLNGHKGWVVSVDFASDNRHLVT 246 Query: 302 VSTDKSARVFDIS 264 STD S R++D++ Sbjct: 247 ASTDCSVRIWDLA 259 Score = 48.5 bits (114), Expect = 2e-05 Identities = 39/158 (24%), Positives = 64/158 (40%), Gaps = 43/158 (27%) Frame = -2 Query: 611 GHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCEHD---------------- 480 GH + + I+S A+ S+D +++WDL + T + D Sbjct: 59 GHRLGVISVDINSTGTLAASSSLDSQILLWDLETGRLTKTYDGDPADTWTIAFSPDSRFL 118 Query: 479 -------------------EG--------VTCLAWLGSSRYVASGCIDGMVRIWDSLSGD 381 EG V LA++ +A+G I+G+V I D +G Sbjct: 119 ATGSHTGCVNMINVQTAQKEGSIQLEGKFVYXLAYISDGSKLAAGTINGLVSICDLETGS 178 Query: 380 LARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFDI 267 + + GH V+S++ S DG + S S DK +VFD+ Sbjct: 179 V-QFLDGHATPVRSVSFSPDGRLLASASDDKQIKVFDV 215 Score = 42.0 bits (97), Expect = 0.002 Identities = 30/132 (22%), Positives = 57/132 (43%), Gaps = 3/132 (2%) Frame = -2 Query: 563 WVATGSIDRTLIIWDLARQAIRSTCE---HDEGVTCLAWLGSSRYVASGCIDGMVRIWDS 393 ++ TGS+D LI W+ ++ + H GV + + AS +D + +WD Sbjct: 31 YIITGSLDNGLIAWEWTNSQLKCLYQFEGHRLGVISVDINSTGTLAASSSLDSQILLWDL 90 Query: 392 LSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFDISMFK*EKS*QQQHG*FGW 213 +G L +T+ G ++A S D + + S + ++ + E S Q + G F + Sbjct: 91 ETGRLTKTYDGDPADTWTIAFSPDSRFLATGSHTGCVNMINVQTAQKEGSIQLE-GKFVY 149 Query: 212 SFWPVKSGGLLS 177 + G L+ Sbjct: 150 XLAYISDGSKLA 161
>MORG1_BRARE (Q6DH44) Mitogen-activated protein kinase organizer 1 (MAPK| organizer 1) Length = 315 Score = 56.2 bits (134), Expect = 8e-08 Identities = 39/136 (28%), Positives = 63/136 (46%), Gaps = 3/136 (2%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDL---ARQAIRST 492 +V + + SGQV L GH + C+ + + +GSID T+ WD + I+ Sbjct: 90 TVILWDVASGQVTRKLRGHAGKVNCVQFNEEATVMLSGSIDGTVRCWDTRSRRMEPIQIL 149 Query: 491 CEHDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNS 312 E +G++ L S + +G +DG VR +D G L + G + + S DG Sbjct: 150 DESQDGISSLK--VSEHELLTGSVDGRVRRYDLRMGQLQVDYIG--SPITCVCFSRDGQC 205 Query: 311 IVSVSTDKSARVFDIS 264 +S S D + R+ D S Sbjct: 206 TLSSSLDSTVRLLDKS 221 Score = 38.9 bits (89), Expect = 0.014 Identities = 27/112 (24%), Positives = 51/112 (45%), Gaps = 2/112 (1%) Frame = -2 Query: 599 SIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCEHDEGVTCLAWLGS--SRYVASG 426 ++ + ++ N++ T D++L +W ++R + T G L GS + + S Sbjct: 27 AVRAVRFNADGNYLLTCGSDKSLKLWSVSRGTLLKTYS-GHGYEVLDADGSYDNSQLCSC 85 Query: 425 CIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFD 270 D V +WD SG + R GH V + + + ++S S D + R +D Sbjct: 86 SSDKTVILWDVASGQVTRKLRGHAGKVNCVQFNEEATVMLSGSIDGTVRCWD 137 Score = 35.0 bits (79), Expect = 0.20 Identities = 18/70 (25%), Positives = 35/70 (50%) Frame = -2 Query: 473 VTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVST 294 V + + Y+ + D +++W G L +T+SGH V S D + + S S+ Sbjct: 28 VRAVRFNADGNYLLTCGSDKSLKLWSVSRGTLLKTYSGHGYEVLDADGSYDNSQLCSCSS 87 Query: 293 DKSARVFDIS 264 DK+ ++D++ Sbjct: 88 DKTVILWDVA 97
>WDR31_MOUSE (Q9JHB4) WD-repeat protein 31 (Spermatid WD-repeat protein) (spWD)| Length = 367 Score = 56.2 bits (134), Expect = 8e-08 Identities = 31/109 (28%), Positives = 52/109 (47%), Gaps = 1/109 (0%) Frame = -2 Query: 617 LVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLAR-QAIRSTCEHDEGVTCLAWLGSSR 441 L GH + + +S + + TGS D +L++WD+ Q + VT L W+ S Sbjct: 142 LSGHAMVVTGLAVSPDSSQLCTGSRDNSLLLWDVGTGQCVERASVSRNLVTHLCWVPSEP 201 Query: 440 YVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVST 294 Y+ D +R+WDS +A F + + VS DG++ +S S+ Sbjct: 202 YIVQTSEDKTIRLWDSRGLQMAHMFPTKQHIQTHCEVSVDGHTCISCSS 250 Score = 48.5 bits (114), Expect = 2e-05 Identities = 35/125 (28%), Positives = 56/125 (44%), Gaps = 2/125 (1%) Frame = -2 Query: 638 SGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDL--ARQAIRSTCEHDEGVTC 465 +G++V GH I I + N + S D+T+++WDL + + H VT Sbjct: 92 TGRMVKRFTGHEREITKIACIPKANQFFSASRDKTVLMWDLQGSSHPRQQLSGHAMVVTG 151 Query: 464 LAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKS 285 LA S + +G D + +WD +G S R++V L IV S DK+ Sbjct: 152 LAVSPDSSQLCTGSRDNSLLLWDVGTGQCVERASVSRNLVTHLCWVPSEPYIVQTSEDKT 211 Query: 284 ARVFD 270 R++D Sbjct: 212 IRLWD 216 Score = 41.2 bits (95), Expect = 0.003 Identities = 35/121 (28%), Positives = 52/121 (42%), Gaps = 3/121 (2%) Frame = -2 Query: 620 SLVGHTNSIECIGISSRYNWVATGSIDRTLII--WDLARQAIRSTCEHDEGVTCLAWLGS 447 S++ NS CI +G D+T + W R R T H+ +T +A + Sbjct: 66 SVIATLNSDLCI----------SGGKDKTAVAYNWKTGRMVKRFT-GHEREITKIACIPK 114 Query: 446 SRYVASGCIDGMVRIWDSLSGDLART-FSGHRDVVQSLAVSADGNSIVSVSTDKSARVFD 270 + S D V +WD R SGH VV LAVS D + + + S D S ++D Sbjct: 115 ANQFFSASRDKTVLMWDLQGSSHPRQQLSGHAMVVTGLAVSPDSSQLCTGSRDNSLLLWD 174 Query: 269 I 267 + Sbjct: 175 V 175
>PRP4_HUMAN (O43172) U4/U6 small nuclear ribonucleoprotein Prp4 (U4/U6 snRNP 60| kDa protein) (WD splicing factor Prp4) (hPrp4) Length = 522 Score = 55.8 bits (133), Expect = 1e-07 Identities = 35/126 (27%), Positives = 60/126 (47%), Gaps = 2/126 (1%) Frame = -2 Query: 644 INSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLA-RQAIRSTCEHDEGVT 468 + +G+ + L GH I I S +ATGS D T +WDL R+ + + H VT Sbjct: 394 LRTGRCIMFLEGHLKEIYGINFSPNGYHIATGSGDNTCKVWDLRQRRCVYTIPAHQNLVT 453 Query: 467 CLAWLG-SSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTD 291 + + ++ +G D +IW +T +GH V L +S+DG I + S D Sbjct: 454 GVKFEPIHGNFLLTGAYDNTAKIWTHPGWSPLKTLAGHEGKVMGLDISSDGQLIATCSYD 513 Query: 290 KSARVF 273 ++ +++ Sbjct: 514 RTFKLW 519 Score = 54.7 bits (130), Expect = 2e-07 Identities = 35/133 (26%), Positives = 62/133 (46%), Gaps = 1/133 (0%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDL-ARQAIRSTCE 486 SV + S++S + V + GHT + + ++ T DR+ +WDL A++ I Sbjct: 304 SVKLWSLDSDEPVADIEGHTVRVARVMWHPSGRFLGTTCYDRSWRLWDLEAQEEILHQEG 363 Query: 485 HDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIV 306 H GV +A+ +G +D R+WD +G GH + + S +G I Sbjct: 364 HSMGVYDIAFHQDGSLAGTGGLDAFGRVWDLRTGRCIMFLEGHLKEIYGINFSPNGYHIA 423 Query: 305 SVSTDKSARVFDI 267 + S D + +V+D+ Sbjct: 424 TGSGDNTCKVWDL 436
>PRP4_PONPY (Q5NVD0) U4/U6 small nuclear ribonucleoprotein Prp4 (U4/U6 snRNP 60| kDa protein) (WD splicing factor Prp4) Length = 521 Score = 55.8 bits (133), Expect = 1e-07 Identities = 35/126 (27%), Positives = 60/126 (47%), Gaps = 2/126 (1%) Frame = -2 Query: 644 INSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLA-RQAIRSTCEHDEGVT 468 + +G+ + L GH I I S +ATGS D T +WDL R+ + + H VT Sbjct: 393 LRTGRCIMFLEGHLKEIYGINFSPNGYHIATGSGDNTCKVWDLRQRRCVYTIPAHQNLVT 452 Query: 467 CLAWLG-SSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTD 291 + + ++ +G D +IW +T +GH V L +S+DG I + S D Sbjct: 453 GVKFEPIHGNFLLTGAYDNTAKIWTHPGWSPLKTLAGHEGKVMGLDISSDGQLIATCSYD 512 Query: 290 KSARVF 273 ++ +++ Sbjct: 513 RTFKLW 518 Score = 54.7 bits (130), Expect = 2e-07 Identities = 35/133 (26%), Positives = 62/133 (46%), Gaps = 1/133 (0%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDL-ARQAIRSTCE 486 SV + S++S + V + GHT + + ++ T DR+ +WDL A++ I Sbjct: 303 SVKLWSLDSDEPVADIEGHTVRVARVMWHPSGRFLGTTCYDRSWRLWDLEAQEEILHQEG 362 Query: 485 HDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIV 306 H GV +A+ +G +D R+WD +G GH + + S +G I Sbjct: 363 HSMGVYDIAFHQDGSLAGTGGLDAFGRVWDLRTGRCIMFLEGHLKEIYGINFSPNGYHIA 422 Query: 305 SVSTDKSARVFDI 267 + S D + +V+D+ Sbjct: 423 TGSGDNTCKVWDL 435
>WDR31_HUMAN (Q8NA23) WD-repeat protein 31| Length = 367 Score = 55.8 bits (133), Expect = 1e-07 Identities = 33/115 (28%), Positives = 52/115 (45%), Gaps = 1/115 (0%) Frame = -2 Query: 638 SGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLAR-QAIRSTCEHDEGVTCL 462 S Q L GH + + +S + + TGS D TL++WD+ Q++ VT L Sbjct: 135 SSQPRQQLCGHAMVVTGLAVSPDSSQLCTGSRDNTLLLWDVVTGQSVERASVSRNVVTHL 194 Query: 461 AWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVS 297 W+ Y+ D +R+WDS +A F + + VS DG+ +S S Sbjct: 195 CWVPREPYILQTSEDKTLRLWDSRGLQVAHMFPAKQHIQTYCEVSVDGHKCISCS 249 Score = 51.6 bits (122), Expect = 2e-06 Identities = 36/125 (28%), Positives = 58/125 (46%), Gaps = 2/125 (1%) Frame = -2 Query: 638 SGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDL--ARQAIRSTCEHDEGVTC 465 +G VV GH + I + + + + S DR +++WDL + Q + C H VT Sbjct: 92 TGNVVKRFKGHEHEITKVACIPKSSQFFSASRDRMVMMWDLHGSSQPRQQLCGHAMVVTG 151 Query: 464 LAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKS 285 LA S + +G D + +WD ++G S R+VV L I+ S DK+ Sbjct: 152 LAVSPDSSQLCTGSRDNTLLLWDVVTGQSVERASVSRNVVTHLCWVPREPYILQTSEDKT 211 Query: 284 ARVFD 270 R++D Sbjct: 212 LRLWD 216 Score = 38.9 bits (89), Expect = 0.014 Identities = 31/120 (25%), Positives = 53/120 (44%), Gaps = 2/120 (1%) Frame = -2 Query: 620 SLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLAR-QAIRSTCEHDEGVTCLAWLGSS 444 S+V NS C+ +G D+T++ ++ ++ H+ +T +A + S Sbjct: 66 SVVAALNSDLCV----------SGGKDKTVVAYNWKTGNVVKRFKGHEHEITKVACIPKS 115 Query: 443 RYVASGCIDGMVRIWDSLSGDLART-FSGHRDVVQSLAVSADGNSIVSVSTDKSARVFDI 267 S D MV +WD R GH VV LAVS D + + + S D + ++D+ Sbjct: 116 SQFFSASRDRMVMMWDLHGSSQPRQQLCGHAMVVTGLAVSPDSSQLCTGSRDNTLLLWDV 175
>GBLP_HYDAT (Q25189) Guanine nucleotide-binding protein beta subunit-like| protein (Receptor of activated protein kinase C) (RACK) Length = 317 Score = 55.8 bits (133), Expect = 1e-07 Identities = 33/137 (24%), Positives = 67/137 (48%), Gaps = 4/137 (2%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCE- 486 ++ + +N G VGHT + + S+ + +GS D T+ +W+ Q + + Sbjct: 86 TLRLWDLNQGITTKQFVGHTKDVLSVAFSADNRQIVSGSRDNTIKLWNTLGQCKYTIQDE 145 Query: 485 -HDEGVTCLAWLGSSR--YVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGN 315 H E V+C+ + +++ + S D MV++W+ + L GH + ++ VS DG+ Sbjct: 146 SHSEWVSCVRFSPNTQNPIIVSCGWDKMVKVWNLTNCKLKTNHFGHTGYLNAVTVSPDGS 205 Query: 314 SIVSVSTDKSARVFDIS 264 S D +A ++D++ Sbjct: 206 LCASGGKDGNAMLWDLN 222 Score = 49.3 bits (116), Expect = 1e-05 Identities = 35/126 (27%), Positives = 58/126 (46%), Gaps = 8/126 (6%) Frame = -2 Query: 623 GSLVGHTNSIECIGISSRY-NWVATGSIDRTLIIWDLARQ-------AIRSTCEHDEGVT 468 G+L GH + I + + + + + S D+TLI W L R + H+ V+ Sbjct: 8 GTLKGHNGWVTQIATTPQNPDLILSASRDKTLIQWQLTRDDQTNYGFPKKCLTGHNHFVS 67 Query: 467 CLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDK 288 + ++ S D +R+WD G + F GH V S+A SAD IVS S D Sbjct: 68 DVVLSSDGQFALSCSWDKTLRLWDLNQGITTKQFVGHTKDVLSVAFSADNRQIVSGSRDN 127 Query: 287 SARVFD 270 + ++++ Sbjct: 128 TIKLWN 133 Score = 40.0 bits (92), Expect = 0.006 Identities = 34/126 (26%), Positives = 56/126 (44%), Gaps = 10/126 (7%) Frame = -2 Query: 611 GHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCEHDEGVTCLAWLGSSRYVA 432 GHT + + +S + A+G D ++WDL T + + L + +RY Sbjct: 190 GHTGYLNAVTVSPDGSLCASGGKDGNAMLWDLNEGKHLYTLDGGNVINALCF-SPNRYWL 248 Query: 431 SGCIDGMVRIWD----SLSGDLA------RTFSGHRDVVQSLAVSADGNSIVSVSTDKSA 282 M++IWD S+ +L T S D + SLA SADG ++ + TD Sbjct: 249 CAATGPMIKIWDLEMKSVVDELKPGVIGISTKSRAADCI-SLAWSADGQTLFAGYTDNLI 307 Query: 281 RVFDIS 264 RV+ ++ Sbjct: 308 RVWQVT 313 Score = 30.4 bits (67), Expect = 4.9 Identities = 12/37 (32%), Positives = 23/37 (62%) Frame = -2 Query: 374 RTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFDIS 264 + +GH V + +S+DG +S S DK+ R++D++ Sbjct: 57 KCLTGHNHFVSDVVLSSDGQFALSCSWDKTLRLWDLN 93 Score = 29.6 bits (65), Expect = 8.4 Identities = 21/96 (21%), Positives = 40/96 (41%), Gaps = 10/96 (10%) Frame = -2 Query: 656 HIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIR------- 498 H+ +++ G V+ +L C + + ATG + + IWDL +++ Sbjct: 226 HLYTLDGGNVINAL--------CFSPNRYWLCAATGPMIK---IWDLEMKSVVDELKPGV 274 Query: 497 ---STCEHDEGVTCLAWLGSSRYVASGCIDGMVRIW 399 ST LAW + + +G D ++R+W Sbjct: 275 IGISTKSRAADCISLAWSADGQTLFAGYTDNLIRVW 310
>DIP2_YEAST (Q12220) DOM34-interacting protein 2 (U3 small nucleolar| RNA-associated protein 12) (U3 snoRNA-associated protein 12) Length = 943 Score = 55.5 bits (132), Expect = 1e-07 Identities = 37/132 (28%), Positives = 62/132 (46%), Gaps = 1/132 (0%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLA-RQAIRSTCE 486 +V + ++S + SL GH + I IS + T S D+ + IW L +S Sbjct: 554 TVKVFFLDSMKFYLSLYGHKLPVLSIDISFDSKMIITSSADKNIKIWGLDFGDCHKSLFA 613 Query: 485 HDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIV 306 H + + + +L S S D +V+ WD + + H+ V +LAV+ DG +V Sbjct: 614 HQDSIMNVKFLPQSHNFFSCSKDAVVKYWDGEKFECIQKLYAHQSEVWALAVATDGGFVV 673 Query: 305 SVSTDKSARVFD 270 S S D S R+++ Sbjct: 674 SSSHDHSIRIWE 685 Score = 45.8 bits (107), Expect = 1e-04 Identities = 29/134 (21%), Positives = 58/134 (43%), Gaps = 1/134 (0%) Frame = -2 Query: 659 VHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQA-IRSTCEH 483 + + + S V+ + GH +I + + +GS D +I+WDL + + H Sbjct: 103 IKVWDLMSKTVLLNFNGHKAAITLLQFDGTGTRLISGSKDSNIIVWDLVGEVGLYKLRSH 162 Query: 482 DEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVS 303 + +T W ++ S DGM+++WD + T H LAV D +++ Sbjct: 163 KDSITGF-WCQGEDWLISTSKDGMIKLWDLKTHQCIETHIAHTGECWGLAVKDD--LLIT 219 Query: 302 VSTDKSARVFDISM 261 TD +++ + + Sbjct: 220 TGTDSQVKIWKLDI 233 Score = 42.0 bits (97), Expect = 0.002 Identities = 31/139 (22%), Positives = 60/139 (43%), Gaps = 17/139 (12%) Frame = -2 Query: 608 HTNSIECIGISSRYNWVATGSIDRTLIIWD-----------------LARQAIRSTCEHD 480 H +I + ++S + TGS D+T+ WD + + +T E Sbjct: 472 HDAAIWSLDLTSDGKRLVTGSADKTVKFWDFKVENSLVPGTKNKFLPVLKLHHDTTLELT 531 Query: 479 EGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSV 300 + + C+ RY+A +D V+++ S + GH+ V S+ +S D I++ Sbjct: 532 DDILCVRVSPDDRYLAISLLDNTVKVFFLDSMKFYLSLYGHKLPVLSIDISFDSKMIITS 591 Query: 299 STDKSARVFDISMFK*EKS 243 S DK+ +++ + KS Sbjct: 592 SADKNIKIWGLDFGDCHKS 610 Score = 41.2 bits (95), Expect = 0.003 Identities = 17/57 (29%), Positives = 32/57 (56%) Frame = -2 Query: 437 VASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFDI 267 +A G DG++++WD +S + F+GH+ + L G ++S S D + V+D+ Sbjct: 94 LAVGYADGVIKVWDLMSKTVLLNFNGHKAAITLLQFDGTGTRLISGSKDSNIIVWDL 150 Score = 35.0 bits (79), Expect = 0.20 Identities = 24/118 (20%), Positives = 52/118 (44%), Gaps = 1/118 (0%) Frame = -2 Query: 605 TNSIECIGISSRYNWVATGSIDRTLIIWDL-ARQAIRSTCEHDEGVTCLAWLGSSRYVAS 429 T+ I C+ +S ++A +D T+ ++ L + + S H V + S+ + + Sbjct: 531 TDDILCVRVSPDDRYLAISLLDNTVKVFFLDSMKFYLSLYGHKLPVLSIDISFDSKMIIT 590 Query: 428 GCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFDISMFK 255 D ++IW GD ++ H+D + ++ ++ S S D + +D F+ Sbjct: 591 SSADKNIKIWGLDFGDCHKSLFAHQDSIMNVKFLPQSHNFFSCSKDAVVKYWDGEKFE 648
>GBLP_ORYSA (P49027) Guanine nucleotide-binding protein beta subunit-like| protein (GPB-LR) (RWD) Length = 334 Score = 55.5 bits (132), Expect = 1e-07 Identities = 35/136 (25%), Positives = 59/136 (43%), Gaps = 16/136 (11%) Frame = -2 Query: 629 VVGSLVGHTNSIECIGIS-SRYNWVATGSIDRTLIIWDLARQA---------------IR 498 + G + GH + + I ++ + S D++L++WDL R Sbjct: 10 LAGVMHGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPVQNVGEGAGASEYGVPFR 69 Query: 497 STCEHDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADG 318 H V + ++ SG DG +R+WD +G R F GH V S+A S D Sbjct: 70 RLTGHSHFVQDVVLSSDGQFALSGSWDGELRLWDLSTGVTTRRFVGHDKDVLSVAFSVDN 129 Query: 317 NSIVSVSTDKSARVFD 270 IVS S D++ ++++ Sbjct: 130 RQIVSASRDRTIKLWN 145 Score = 44.3 bits (103), Expect = 3e-04 Identities = 32/138 (23%), Positives = 57/138 (41%), Gaps = 11/138 (7%) Frame = -2 Query: 644 INSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDL---ARQAIRSTCEHDEG 474 +++G VGH + + S + + S DRT+ +W+ + I EG Sbjct: 104 LSTGVTTRRFVGHDKDVLSVAFSVDNRQIVSASRDRTIKLWNTLGECKYTIGGDLGGGEG 163 Query: 473 VTCLAWLGSSRY--------VASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADG 318 W+ R+ + SG D V++W+ + L GH V ++AVS DG Sbjct: 164 HN--GWVSCVRFSPNTFQPTIVSGSWDRTVKVWNLTNCKLRCNLEGHGGYVNAVAVSPDG 221 Query: 317 NSIVSVSTDKSARVFDIS 264 + S D ++D++ Sbjct: 222 SLCASGGKDGVTLLWDLA 239 Score = 41.6 bits (96), Expect = 0.002 Identities = 32/142 (22%), Positives = 64/142 (45%), Gaps = 7/142 (4%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCEH 483 +V + ++ + ++ +L GH + + +S + A+G D ++WDLA + + Sbjct: 190 TVKVWNLTNCKLRCNLEGHGGYVNAVAVSPDGSLCASGGKDGVTLLWDLAEGKRLYSLDA 249 Query: 482 DEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQ-------SLAVSA 324 + L + +RY ++IWD S + + V + SL SA Sbjct: 250 GSIIHSLCF-SPNRYWLCAATQDSIKIWDLESKHIVQDLKPEIPVSKNQMLYCTSLNWSA 308 Query: 323 DGNSIVSVSTDKSARVFDISMF 258 DG+++ + TD + R++ IS F Sbjct: 309 DGSTLYAGYTDGTIRIYKISGF 330 Score = 35.4 bits (80), Expect = 0.15 Identities = 25/89 (28%), Positives = 42/89 (47%), Gaps = 15/89 (16%) Frame = -2 Query: 485 HDEGVTCLAW-LGSSRYVASGCIDGMVRIWD--------------SLSGDLARTFSGHRD 351 H++ VT +A + +S ++ S D + +WD S G R +GH Sbjct: 17 HNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPVQNVGEGAGASEYGVPFRRLTGHSH 76 Query: 350 VVQSLAVSADGNSIVSVSTDKSARVFDIS 264 VQ + +S+DG +S S D R++D+S Sbjct: 77 FVQDVVLSSDGQFALSGSWDGELRLWDLS 105
>GBB3_RAT (P52287) Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta| subunit 3 (Transducin beta chain 3) Length = 340 Score = 55.1 bits (131), Expect = 2e-07 Identities = 35/134 (26%), Positives = 61/134 (45%), Gaps = 3/134 (2%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCEH 483 S + + G + GH + I I + TGS D + ++DL + H Sbjct: 207 SAKLWDVREGTCRQTFTGHESDINAICFFPNGEAICTGSDDASCRLFDLRADQELTAYSH 266 Query: 482 DE---GVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNS 312 + G+T +A+ S R + +G D +WDSL + SGH + V L V+ADG + Sbjct: 267 ESIICGITSVAFSLSGRLLFAGYDDFNCNVWDSLKCERVGVLSGHDNRVSCLGVTADGMA 326 Query: 311 IVSVSTDKSARVFD 270 + + S D ++++ Sbjct: 327 VATGSWDSFLKIWN 340 Score = 53.9 bits (128), Expect = 4e-07 Identities = 37/136 (27%), Positives = 60/136 (44%), Gaps = 4/136 (2%) Frame = -2 Query: 662 SVHIVSINSGQVVGS--LVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTC 489 S++ + G V S L HT + C N + T S D T +WD+ ++ Sbjct: 122 SIYSLKSREGNVKVSRELSAHTGYLSCCRFLDDNN-IVTSSGDTTCALWDIETGQQKTVF 180 Query: 488 EHDEGVTCLAWLGSSRY--VASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGN 315 G C++ S Y SG D ++WD G +TF+GH + ++ +G Sbjct: 181 VGHTG-DCMSLAVSPDYKLFISGACDASAKLWDVREGTCRQTFTGHESDINAICFFPNGE 239 Query: 314 SIVSVSTDKSARVFDI 267 +I + S D S R+FD+ Sbjct: 240 AICTGSDDASCRLFDL 255 Score = 36.6 bits (83), Expect = 0.069 Identities = 32/123 (26%), Positives = 54/123 (43%), Gaps = 5/123 (4%) Frame = -2 Query: 620 SLVGHTNSIECIGISSRYNWVATGSIDRTLIIWD-LARQAIRSTCEHDEGVTCLAWLGSS 444 +L GH I + ++ + + S D LI+WD + + V A+ S Sbjct: 50 TLRGHLAKIYAMHWATDSKLLVSASQDGKLIVWDTYTTNKVHAIPLRSSWVMTCAYAPSG 109 Query: 443 RYVASGCIDGMVRIWDSLSGD----LARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARV 276 +VA G +D M I+ S + ++R S H + S D N+IV+ S D + + Sbjct: 110 NFVACGGLDNMCSIYSLKSREGNVKVSRELSAHTGYL-SCCRFLDDNNIVTSSGDTTCAL 168 Query: 275 FDI 267 +DI Sbjct: 169 WDI 171
>GBB5_RAT (P62882) Guanine nucleotide-binding protein beta subunit 5| (Transducin beta chain 5) (Gbeta5) Length = 353 Score = 55.1 bits (131), Expect = 2e-07 Identities = 35/122 (28%), Positives = 57/122 (46%), Gaps = 4/122 (3%) Frame = -2 Query: 620 SLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDL-ARQAIRSTCEHDEGVTCLAWLGS- 447 S+ HTN + ++ + T S D T +WD+ + Q ++S H V CL S Sbjct: 148 SVAMHTNYLSACSFTNSDMQILTASGDGTCALWDVESGQLLQSFHGHGADVLCLDLAPSE 207 Query: 446 --SRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVF 273 + +V+ GC D +WD SG + F H V S+ G++ S S D + R++ Sbjct: 208 TGNTFVSGGC-DKKAMVWDMRSGQCVQAFETHESDVNSVRYYPSGDAFASGSDDATCRLY 266 Query: 272 DI 267 D+ Sbjct: 267 DL 268 Score = 50.4 bits (119), Expect = 5e-06 Identities = 37/127 (29%), Positives = 58/127 (45%), Gaps = 3/127 (2%) Frame = -2 Query: 644 INSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQ---AIRSTCEHDEG 474 + SGQ V + H + + + + A+GS D T ++DL AI S G Sbjct: 226 MRSGQCVQAFETHESDVNSVRYYPSGDAFASGSDDATCRLYDLRADREVAIYSKESIIFG 285 Query: 473 VTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVST 294 + + + S R + +G D + +WD L G GH + V +L VS DG + S S Sbjct: 286 ASSVDFSLSGRLLFAGYNDYTINVWDVLKGSRVSILFGHENRVSTLRVSPDGTAFCSGSW 345 Query: 293 DKSARVF 273 D + RV+ Sbjct: 346 DHTLRVW 352 Score = 43.9 bits (102), Expect = 4e-04 Identities = 27/80 (33%), Positives = 41/80 (51%), Gaps = 2/80 (2%) Frame = -2 Query: 500 RSTCEHDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGH-RDVV-QSLAVS 327 +S H ++ ++ S + + DG +WD SG L ++F GH DV+ LA S Sbjct: 147 KSVAMHTNYLSACSFTNSDMQILTASGDGTCALWDVESGQLLQSFHGHGADVLCLDLAPS 206 Query: 326 ADGNSIVSVSTDKSARVFDI 267 GN+ VS DK A V+D+ Sbjct: 207 ETGNTFVSGGCDKKAMVWDM 226 Score = 35.0 bits (79), Expect = 0.20 Identities = 20/79 (25%), Positives = 32/79 (40%) Frame = -2 Query: 485 HDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIV 306 H V C+ W R + S DG V +WDS + + + V + A + G +I Sbjct: 62 HGNKVLCMDWCKDKRRIVSSSQDGKVIVWDSFTTNKEHAVTMPCTWVMACAYAPSGCAIA 121 Query: 305 SVSTDKSARVFDISMFK*E 249 D V+ ++ K E Sbjct: 122 CGGLDNKCSVYPLTFDKNE 140 Score = 32.3 bits (72), Expect = 1.3 Identities = 18/66 (27%), Positives = 30/66 (45%) Frame = -2 Query: 620 SLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCEHDEGVTCLAWLGSSR 441 +L GH N + C+ + + S D +I+WD + + EH + C W+ + Sbjct: 58 TLKGHGNKVLCMDWCKDKRRIVSSSQDGKVIVWD----SFTTNKEHAVTMPC-TWVMACA 112 Query: 440 YVASGC 423 Y SGC Sbjct: 113 YAPSGC 118
>PRP4_MOUSE (Q9DAW6) U4/U6 small nuclear ribonucleoprotein Prp4 (U4/U6 snRNP 60| kDa protein) (WD splicing factor Prp4) Length = 521 Score = 55.1 bits (131), Expect = 2e-07 Identities = 35/126 (27%), Positives = 60/126 (47%), Gaps = 2/126 (1%) Frame = -2 Query: 644 INSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLA-RQAIRSTCEHDEGVT 468 + +G+ + L GH I I S +ATGS D T +WDL R+ + + H VT Sbjct: 393 LRTGRCIMFLEGHLKEIYGINFSPNGYHIATGSGDNTCKVWDLRQRRCVYTIPAHQNLVT 452 Query: 467 CLAWLG-SSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTD 291 + + ++ +G D +IW +T +GH V L +S+DG I + S D Sbjct: 453 GVKFEPIHGDFLLTGAYDNTAKIWTHPGWSPLKTLAGHEGKVMGLDISSDGQLIATCSYD 512 Query: 290 KSARVF 273 ++ +++ Sbjct: 513 RTFKLW 518 Score = 54.7 bits (130), Expect = 2e-07 Identities = 35/133 (26%), Positives = 62/133 (46%), Gaps = 1/133 (0%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDL-ARQAIRSTCE 486 SV + S++S + V + GHT + + ++ T DR+ +WDL A++ I Sbjct: 303 SVKLWSLDSDEPVADIEGHTVRVARVMWHPSGRFLGTTCYDRSWRLWDLEAQEEILHQEG 362 Query: 485 HDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIV 306 H GV +A+ +G +D R+WD +G GH + + S +G I Sbjct: 363 HSMGVYDIAFHQDGSLAGTGGLDAFGRVWDLRTGRCIMFLEGHLKEIYGINFSPNGYHIA 422 Query: 305 SVSTDKSARVFDI 267 + S D + +V+D+ Sbjct: 423 TGSGDNTCKVWDL 435
>YIRF_SCHPO (Q9P7I3) Hypothetical WD-repeat protein C664.15 in chromosome I| Length = 651 Score = 55.1 bits (131), Expect = 2e-07 Identities = 42/153 (27%), Positives = 73/153 (47%), Gaps = 26/153 (16%) Frame = -2 Query: 647 SINSGQVVGSLV----GHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQA-IRSTCEH 483 S+N +VG+LV H+ I + S + +AT S D+T+ +WD+A + S H Sbjct: 314 SVNQNYIVGNLVKQFQAHSEYITSLDFSHPFGTLATASTDKTVKVWDMAGVVYLGSLKGH 373 Query: 482 DEGVTCLAWLGSSRYVASGCIDGMVRIW---------------------DSLSGDLARTF 366 + V+CLA S ++A+G +D VR+W D + Sbjct: 374 SDYVSCLAIQDS--FIATGSMDTTVRLWNLDNDVLHKDNPVEESLNSPPDQPVDNATNVL 431 Query: 365 SGHRDVVQSLAVSADGNSIVSVSTDKSARVFDI 267 + H V +LA+S+D + +++ + DK+ R +DI Sbjct: 432 TSHTAPVTALALSSD-DVLITGADDKTVRQWDI 463 Score = 53.5 bits (127), Expect = 5e-07 Identities = 42/138 (30%), Positives = 63/138 (45%), Gaps = 21/138 (15%) Frame = -2 Query: 617 LVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCE------HDEGVTCLAW 456 L HT + + +SS + + TG+ D+T+ WD+ T + HD + + Sbjct: 431 LTSHTAPVTALALSSD-DVLITGADDKTVRQWDIVTGRCIQTLDFVWAETHDTSTSQI-- 487 Query: 455 LGSSRY---------------VASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSAD 321 L S Y VASG +DG++RIWD G R+F GH + SL D Sbjct: 488 LVSDTYKQEPFIRALDCLDAAVASGTVDGLIRIWDLRIGLPVRSFIGHTAPISSL--QFD 545 Query: 320 GNSIVSVSTDKSARVFDI 267 N + S S D S R++D+ Sbjct: 546 SNHLYSGSYDNSVRIWDL 563 Score = 38.1 bits (87), Expect = 0.024 Identities = 23/60 (38%), Positives = 33/60 (55%), Gaps = 1/60 (1%) Frame = -2 Query: 560 VATGSIDRTLIIWDLA-RQAIRSTCEHDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSG 384 VA+G++D + IWDL +RS H ++ L + S ++ SG D VRIWD SG Sbjct: 509 VASGTVDGLIRIWDLRIGLPVRSFIGHTAPISSLQF--DSNHLYSGSYDNSVRIWDLRSG 566
>TIPD_DICDI (O15736) Protein tipD| Length = 612 Score = 55.1 bits (131), Expect = 2e-07 Identities = 43/138 (31%), Positives = 65/138 (47%), Gaps = 3/138 (2%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCEH 483 S + + G+ +L GH + G N V TGS DRT+ +WDL + T Sbjct: 389 SARLWNTELGRSRHTLTGHIGKVYT-GKFINSNRVVTGSHDRTIKLWDLQKGYCTRTIFC 447 Query: 482 DEGVTCLAWLGSS-RYVASGCIDGMVRIWDSLSGDLARTFSG-HRDVVQSLAVS-ADGNS 312 L LG S ++ASG +D VR WDS +G+ + S H + S+ S + N Sbjct: 448 FSSCNDLVILGGSGTHLASGHVDHSVRFWDSNAGEPTQVLSSIHEGQITSITNSPTNTNQ 507 Query: 311 IVSVSTDKSARVFDISMF 258 I++ S D + ++ DI F Sbjct: 508 ILTNSRDHTLKIIDIRTF 525 Score = 45.8 bits (107), Expect = 1e-04 Identities = 22/75 (29%), Positives = 40/75 (53%) Frame = -2 Query: 485 HDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIV 306 H+ + C+A+ +A+G D V++WD +SG T G + S++ S + SI+ Sbjct: 323 HNSEIYCMAFNSIGNLLATGGGDKCVKVWDVISGQQKSTLLGASQSIVSVSFSPNDESIL 382 Query: 305 SVSTDKSARVFDISM 261 S D SAR+++ + Sbjct: 383 GTSNDNSARLWNTEL 397 Score = 45.8 bits (107), Expect = 1e-04 Identities = 27/116 (23%), Positives = 57/116 (49%), Gaps = 1/116 (0%) Frame = -2 Query: 611 GHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRST-CEHDEGVTCLAWLGSSRYV 435 GH + I C+ +S N +ATG D+ + +WD+ +ST + + +++ + + Sbjct: 322 GHNSEIYCMAFNSIGNLLATGGGDKCVKVWDVISGQQKSTLLGASQSIVSVSFSPNDESI 381 Query: 434 ASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFDI 267 D R+W++ G T +GH V + + N +V+ S D++ +++D+ Sbjct: 382 LGTSNDNSARLWNTELGRSRHTLTGHIGKVYT-GKFINSNRVVTGSHDRTIKLWDL 436 Score = 43.9 bits (102), Expect = 4e-04 Identities = 38/130 (29%), Positives = 57/130 (43%), Gaps = 5/130 (3%) Frame = -2 Query: 647 SINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLAR-QAIRS--TCEHDE 477 SI+ GQ+ TN+ N + T S D TL I D+ IR+ E+ Sbjct: 489 SIHEGQITSITNSPTNT----------NQILTNSRDHTLKIIDIRTFDTIRTFKDPEYRN 538 Query: 476 GV--TCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVS 303 G+ T +W RY+ASG IDG + IWD+ +G + + V +G+S+ Sbjct: 539 GLNWTKASWSPDGRYIASGSIDGSICIWDATNGKTVKVLT---------KVHNNGSSVCC 589 Query: 302 VSTDKSARVF 273 S A +F Sbjct: 590 CSWSPLANIF 599 Score = 40.8 bits (94), Expect = 0.004 Identities = 34/133 (25%), Positives = 53/133 (39%), Gaps = 3/133 (2%) Frame = -2 Query: 659 VHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCEHD 480 V + + SGQ +L+G + SI + S + S D + +W+ R T Sbjct: 348 VKVWDVISGQQKSTLLGASQSIVSVSFSPNDESILGTSNDNSARLWNTELGRSRHTLTGH 407 Query: 479 EGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLART---FSGHRDVVQSLAVSADGNSI 309 G +S V +G D +++WD G RT FS D+V + G + Sbjct: 408 IGKVYTGKFINSNRVVTGSHDRTIKLWDLQKGYCTRTIFCFSSCNDLV---ILGGSGTHL 464 Query: 308 VSVSTDKSARVFD 270 S D S R +D Sbjct: 465 ASGHVDHSVRFWD 477
>GBB5_MOUSE (P62881) Guanine nucleotide-binding protein beta subunit 5| (Transducin beta chain 5) (Gbeta5) Length = 395 Score = 55.1 bits (131), Expect = 2e-07 Identities = 35/122 (28%), Positives = 57/122 (46%), Gaps = 4/122 (3%) Frame = -2 Query: 620 SLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDL-ARQAIRSTCEHDEGVTCLAWLGS- 447 S+ HTN + ++ + T S D T +WD+ + Q ++S H V CL S Sbjct: 190 SVAMHTNYLSACSFTNSDMQILTASGDGTCALWDVESGQLLQSFHGHGADVLCLDLAPSE 249 Query: 446 --SRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVF 273 + +V+ GC D +WD SG + F H V S+ G++ S S D + R++ Sbjct: 250 TGNTFVSGGC-DKKAMVWDMRSGQCVQAFETHESDVNSVRYYPSGDAFASGSDDATCRLY 308 Query: 272 DI 267 D+ Sbjct: 309 DL 310 Score = 50.4 bits (119), Expect = 5e-06 Identities = 37/127 (29%), Positives = 58/127 (45%), Gaps = 3/127 (2%) Frame = -2 Query: 644 INSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQ---AIRSTCEHDEG 474 + SGQ V + H + + + + A+GS D T ++DL AI S G Sbjct: 268 MRSGQCVQAFETHESDVNSVRYYPSGDAFASGSDDATCRLYDLRADREVAIYSKESIIFG 327 Query: 473 VTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVST 294 + + + S R + +G D + +WD L G GH + V +L VS DG + S S Sbjct: 328 ASSVDFSLSGRLLFAGYNDYTINVWDVLKGSRVSILFGHENRVSTLRVSPDGTAFCSGSW 387 Query: 293 DKSARVF 273 D + RV+ Sbjct: 388 DHTLRVW 394 Score = 43.9 bits (102), Expect = 4e-04 Identities = 27/80 (33%), Positives = 41/80 (51%), Gaps = 2/80 (2%) Frame = -2 Query: 500 RSTCEHDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGH-RDVV-QSLAVS 327 +S H ++ ++ S + + DG +WD SG L ++F GH DV+ LA S Sbjct: 189 KSVAMHTNYLSACSFTNSDMQILTASGDGTCALWDVESGQLLQSFHGHGADVLCLDLAPS 248 Query: 326 ADGNSIVSVSTDKSARVFDI 267 GN+ VS DK A V+D+ Sbjct: 249 ETGNTFVSGGCDKKAMVWDM 268 Score = 35.0 bits (79), Expect = 0.20 Identities = 20/79 (25%), Positives = 32/79 (40%) Frame = -2 Query: 485 HDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIV 306 H V C+ W R + S DG V +WDS + + + V + A + G +I Sbjct: 104 HGNKVLCMDWCKDKRRIVSSSQDGKVIVWDSFTTNKEHAVTMPCTWVMACAYAPSGCAIA 163 Query: 305 SVSTDKSARVFDISMFK*E 249 D V+ ++ K E Sbjct: 164 CGGLDNKCSVYPLTFDKNE 182 Score = 32.3 bits (72), Expect = 1.3 Identities = 18/66 (27%), Positives = 30/66 (45%) Frame = -2 Query: 620 SLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCEHDEGVTCLAWLGSSR 441 +L GH N + C+ + + S D +I+WD + + EH + C W+ + Sbjct: 100 TLKGHGNKVLCMDWCKDKRRIVSSSQDGKVIVWD----SFTTNKEHAVTMPC-TWVMACA 154 Query: 440 YVASGC 423 Y SGC Sbjct: 155 YAPSGC 160
>SPG16_HUMAN (Q8N0X2) Sperm-associated antigen 16 protein (PF20 protein homolog)| Length = 631 Score = 54.7 bits (130), Expect = 2e-07 Identities = 35/115 (30%), Positives = 52/115 (45%), Gaps = 1/115 (0%) Frame = -2 Query: 611 GHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCE-HDEGVTCLAWLGSSRYV 435 GHT+ + + +AT S D T+ +WDL T E H V W +V Sbjct: 392 GHTDWLSDCCFHPSGDKLATSSGDTTVKLWDLCTGDCILTFEGHSRAVWSCTWHSCGNFV 451 Query: 434 ASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFD 270 AS +D +IWD S T GH D V S+ N++++ S DK+ ++D Sbjct: 452 ASSSLDKTSKIWDVNSERCRCTLYGHTDSVNSIEFFPFSNTLLTSSADKTLSIWD 506 Score = 48.5 bits (114), Expect = 2e-05 Identities = 30/132 (22%), Positives = 60/132 (45%), Gaps = 1/132 (0%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTC-E 486 +V + + +G + + GH+ ++ S N+VA+ S+D+T IWD+ + R T Sbjct: 417 TVKLWDLCTGDCILTFEGHSRAVWSCTWHSCGNFVASSSLDKTSKIWDVNSERCRCTLYG 476 Query: 485 HDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIV 306 H + V + + S + + D + IWD+ +G ++ GH + G+ I Sbjct: 477 HTDSVNSIEFFPFSNTLLTSSADKTLSIWDARTGICEQSLYGHMHSINDAIFDPRGHMIA 536 Query: 305 SVSTDKSARVFD 270 S +++D Sbjct: 537 SCDACGVTKLWD 548 Score = 45.8 bits (107), Expect = 1e-04 Identities = 28/116 (24%), Positives = 55/116 (47%), Gaps = 1/116 (0%) Frame = -2 Query: 608 HTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRST-CEHDEGVTCLAWLGSSRYVA 432 H + C+ + + + + DR + L + + T H + ++ + S +A Sbjct: 351 HELPVSCVSMQPHKDILVSCGEDRLWKVLGLPKCNVLLTGFGHTDWLSDCCFHPSGDKLA 410 Query: 431 SGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFDIS 264 + D V++WD +GD TF GH V S + GN + S S DK+++++D++ Sbjct: 411 TSSGDTTVKLWDLCTGDCILTFEGHSRAVWSCTWHSCGNFVASSSLDKTSKIWDVN 466
>GBB5_TAMST (Q80ZD0) Guanine nucleotide-binding protein beta subunit 5| (Transducin beta chain 5) (Gbeta5) Length = 353 Score = 54.7 bits (130), Expect = 2e-07 Identities = 34/122 (27%), Positives = 57/122 (46%), Gaps = 4/122 (3%) Frame = -2 Query: 620 SLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDL-ARQAIRSTCEHDEGVTCLAWLGS- 447 S+ HTN + ++ + T S D T +WD+ + Q ++S H V CL S Sbjct: 148 SVAMHTNYLSACSFTNSDMQILTASGDGTCALWDVESGQLLQSFHGHGADVLCLDLAPSE 207 Query: 446 --SRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVF 273 + +V+ GC D +WD SG + F H + S+ G++ S S D + R++ Sbjct: 208 TGNTFVSGGC-DKKAMVWDMRSGQCVQAFETHESDINSVRYYPSGDAFASGSDDATCRLY 266 Query: 272 DI 267 D+ Sbjct: 267 DL 268 Score = 50.8 bits (120), Expect = 4e-06 Identities = 38/127 (29%), Positives = 58/127 (45%), Gaps = 3/127 (2%) Frame = -2 Query: 644 INSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQ---AIRSTCEHDEG 474 + SGQ V + H + I + + A+GS D T ++DL AI S G Sbjct: 226 MRSGQCVQAFETHESDINSVRYYPSGDAFASGSDDATCRLYDLRADREVAIYSKESIIFG 285 Query: 473 VTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVST 294 + + + S R + +G D + +WD L G GH + V +L VS DG + S S Sbjct: 286 ASSVDFSLSGRLLFAGYNDYTINVWDVLKGSRVSILFGHENRVSTLRVSPDGTAFCSGSW 345 Query: 293 DKSARVF 273 D + RV+ Sbjct: 346 DHTLRVW 352 Score = 43.9 bits (102), Expect = 4e-04 Identities = 27/80 (33%), Positives = 41/80 (51%), Gaps = 2/80 (2%) Frame = -2 Query: 500 RSTCEHDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGH-RDVV-QSLAVS 327 +S H ++ ++ S + + DG +WD SG L ++F GH DV+ LA S Sbjct: 147 KSVAMHTNYLSACSFTNSDMQILTASGDGTCALWDVESGQLLQSFHGHGADVLCLDLAPS 206 Query: 326 ADGNSIVSVSTDKSARVFDI 267 GN+ VS DK A V+D+ Sbjct: 207 ETGNTFVSGGCDKKAMVWDM 226 Score = 35.0 bits (79), Expect = 0.20 Identities = 20/79 (25%), Positives = 32/79 (40%) Frame = -2 Query: 485 HDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIV 306 H V C+ W R + S DG V +WDS + + + V + A + G +I Sbjct: 62 HGNKVLCMDWCKDKRRIVSSSQDGKVIVWDSFTTNKEHAVTMPCTWVMACAYAPSGCAIA 121 Query: 305 SVSTDKSARVFDISMFK*E 249 D V+ ++ K E Sbjct: 122 CGGLDNKCSVYPLTFDKNE 140 Score = 32.3 bits (72), Expect = 1.3 Identities = 18/66 (27%), Positives = 30/66 (45%) Frame = -2 Query: 620 SLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCEHDEGVTCLAWLGSSR 441 +L GH N + C+ + + S D +I+WD + + EH + C W+ + Sbjct: 58 TLKGHGNKVLCMDWCKDKRRIVSSSQDGKVIVWD----SFTTNKEHAVTMPC-TWVMACA 112 Query: 440 YVASGC 423 Y SGC Sbjct: 113 YAPSGC 118
>GBB5_RABIT (Q6PNB6) Guanine nucleotide-binding protein beta subunit 5| (Transducin beta chain 5) (Gbeta5) Length = 353 Score = 54.7 bits (130), Expect = 2e-07 Identities = 34/122 (27%), Positives = 57/122 (46%), Gaps = 4/122 (3%) Frame = -2 Query: 620 SLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDL-ARQAIRSTCEHDEGVTCLAWLGS- 447 S+ HTN + ++ + T S D T +WD+ + Q ++S H V CL S Sbjct: 148 SVAMHTNYLSACSFTNSDMQILTASGDGTCALWDVESGQLLQSFHGHGADVLCLDLAPSE 207 Query: 446 --SRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVF 273 + +V+ GC D +WD SG + F H + S+ G++ S S D + R++ Sbjct: 208 TGNTFVSGGC-DKKAMVWDMRSGQCVQAFETHESDINSVRYYPSGDAFASGSDDATCRLY 266 Query: 272 DI 267 D+ Sbjct: 267 DL 268 Score = 50.1 bits (118), Expect = 6e-06 Identities = 38/127 (29%), Positives = 58/127 (45%), Gaps = 3/127 (2%) Frame = -2 Query: 644 INSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQ---AIRSTCEHDEG 474 + SGQ V + H + I + + A+GS D T ++DL AI S G Sbjct: 226 MRSGQCVQAFETHESDINSVRYYPSGDAFASGSDDATCRLYDLRADREVAIYSKESIIFG 285 Query: 473 VTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVST 294 + + + S R + +G D + +WD L G GH + V +L VS DG + S S Sbjct: 286 ASSVDFSLSGRLLFAGYNDYTINVWDVLKGARVSILFGHENRVSTLRVSPDGTAFCSGSW 345 Query: 293 DKSARVF 273 D + RV+ Sbjct: 346 DHTLRVW 352 Score = 43.9 bits (102), Expect = 4e-04 Identities = 27/80 (33%), Positives = 41/80 (51%), Gaps = 2/80 (2%) Frame = -2 Query: 500 RSTCEHDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGH-RDVV-QSLAVS 327 +S H ++ ++ S + + DG +WD SG L ++F GH DV+ LA S Sbjct: 147 KSVAMHTNYLSACSFTNSDMQILTASGDGTCALWDVESGQLLQSFHGHGADVLCLDLAPS 206 Query: 326 ADGNSIVSVSTDKSARVFDI 267 GN+ VS DK A V+D+ Sbjct: 207 ETGNTFVSGGCDKKAMVWDM 226 Score = 35.0 bits (79), Expect = 0.20 Identities = 20/79 (25%), Positives = 32/79 (40%) Frame = -2 Query: 485 HDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIV 306 H V C+ W R + S DG V +WDS + + + V + A + G +I Sbjct: 62 HGNKVLCMDWCKDKRRIVSSSQDGKVIVWDSFTTNKEHAVTMPCTWVMACAYAPSGCAIA 121 Query: 305 SVSTDKSARVFDISMFK*E 249 D V+ ++ K E Sbjct: 122 CGGLDNKCSVYPLTFDKNE 140 Score = 32.3 bits (72), Expect = 1.3 Identities = 18/66 (27%), Positives = 30/66 (45%) Frame = -2 Query: 620 SLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCEHDEGVTCLAWLGSSR 441 +L GH N + C+ + + S D +I+WD + + EH + C W+ + Sbjct: 58 TLKGHGNKVLCMDWCKDKRRIVSSSQDGKVIVWD----SFTTNKEHAVTMPC-TWVMACA 112 Query: 440 YVASGC 423 Y SGC Sbjct: 113 YAPSGC 118
>GBB5_PONPY (Q5RDY7) Guanine nucleotide-binding protein beta subunit 5| (Transducin beta chain 5) (Gbeta5) Length = 353 Score = 54.7 bits (130), Expect = 2e-07 Identities = 34/122 (27%), Positives = 57/122 (46%), Gaps = 4/122 (3%) Frame = -2 Query: 620 SLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDL-ARQAIRSTCEHDEGVTCLAWLGS- 447 S+ HTN + ++ + T S D T +WD+ + Q ++S H V CL S Sbjct: 148 SVAMHTNYLSACSFTNSDMQILTASGDGTCALWDVESGQLLQSFHGHGADVLCLDLAPSE 207 Query: 446 --SRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVF 273 + +V+ GC D +WD SG + F H + S+ G++ S S D + R++ Sbjct: 208 TGNTFVSGGC-DKKAMVWDMRSGQCVQAFETHESDINSVRYYPSGDAFASGSDDATCRLY 266 Query: 272 DI 267 D+ Sbjct: 267 DL 268 Score = 50.8 bits (120), Expect = 4e-06 Identities = 38/127 (29%), Positives = 58/127 (45%), Gaps = 3/127 (2%) Frame = -2 Query: 644 INSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQ---AIRSTCEHDEG 474 + SGQ V + H + I + + A+GS D T ++DL AI S G Sbjct: 226 MRSGQCVQAFETHESDINSVRYYPSGDAFASGSDDATCRLYDLRADREVAIYSKESIIFG 285 Query: 473 VTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVST 294 + + + S R + +G D + +WD L G GH + V +L VS DG + S S Sbjct: 286 ASSVDFSLSGRLLFAGYNDYTINVWDVLKGSRVSILFGHENRVSTLRVSPDGTAFCSGSW 345 Query: 293 DKSARVF 273 D + RV+ Sbjct: 346 DHTLRVW 352 Score = 43.9 bits (102), Expect = 4e-04 Identities = 27/80 (33%), Positives = 41/80 (51%), Gaps = 2/80 (2%) Frame = -2 Query: 500 RSTCEHDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGH-RDVV-QSLAVS 327 +S H ++ ++ S + + DG +WD SG L ++F GH DV+ LA S Sbjct: 147 KSVAMHTNYLSACSFTNSDMQILTASGDGTCALWDVESGQLLQSFHGHGADVLCLDLAPS 206 Query: 326 ADGNSIVSVSTDKSARVFDI 267 GN+ VS DK A V+D+ Sbjct: 207 ETGNTFVSGGCDKKAMVWDM 226 Score = 35.0 bits (79), Expect = 0.20 Identities = 20/79 (25%), Positives = 32/79 (40%) Frame = -2 Query: 485 HDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIV 306 H V C+ W R + S DG V +WDS + + + V + A + G +I Sbjct: 62 HGNKVLCMDWCKDKRRIVSSSQDGKVIVWDSFTTNKEHAVTMPCTWVMACAYAPSGCAIA 121 Query: 305 SVSTDKSARVFDISMFK*E 249 D V+ ++ K E Sbjct: 122 CGGLDNKCSVYPLTFDKNE 140 Score = 32.3 bits (72), Expect = 1.3 Identities = 18/66 (27%), Positives = 30/66 (45%) Frame = -2 Query: 620 SLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCEHDEGVTCLAWLGSSR 441 +L GH N + C+ + + S D +I+WD + + EH + C W+ + Sbjct: 58 TLKGHGNKVLCMDWCKDKRRIVSSSQDGKVIVWD----SFTTNKEHAVTMPC-TWVMACA 112 Query: 440 YVASGC 423 Y SGC Sbjct: 113 YAPSGC 118
>GBLP_YEAST (P38011) Guanine nucleotide-binding protein beta subunit-like| protein (Receptor of activated protein kinase C 1) (RACK1) (Receptor for activated C kinase) Length = 318 Score = 54.7 bits (130), Expect = 2e-07 Identities = 36/126 (28%), Positives = 58/126 (46%), Gaps = 7/126 (5%) Frame = -2 Query: 623 GSLVGHTNSIECIGISS-RYNWVATGSIDRTLIIWDLARQ------AIRSTCEHDEGVTC 465 G+L GH + + S+ + N + + S D+TLI W L +RS H V Sbjct: 10 GTLEGHNGWVTSLATSAGQPNLLLSASRDKTLISWKLTGDDQKFGVPVRSFKGHSHIVQD 69 Query: 464 LAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKS 285 Y S D +R+WD +G+ + F GH+ V S+ + + I+S S DK+ Sbjct: 70 CTLTADGAYALSASWDKTLRLWDVATGETYQRFVGHKSDVMSVDIDKKASMIISGSRDKT 129 Query: 284 ARVFDI 267 +V+ I Sbjct: 130 IKVWTI 135 Score = 54.3 bits (129), Expect = 3e-07 Identities = 33/160 (20%), Positives = 72/160 (45%), Gaps = 6/160 (3%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCEH 483 ++ + + +G+ VGH + + + I + + + +GS D+T+ +W + Q + + H Sbjct: 87 TLRLWDVATGETYQRFVGHKSDVMSVDIDKKASMIISGSRDKTIKVWTIKGQCLATLLGH 146 Query: 482 DEGVTCLAWLGSSR------YVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSAD 321 ++ V+ + + + + + S D MV+ W+ + F GH + +L S D Sbjct: 147 NDWVSQVRVVPNEKADDDSVTIISAGNDKMVKAWNLNQFQIEADFIGHNSNINTLTASPD 206 Query: 320 GNSIVSVSTDKSARVFDISMFK*EKS*QQQHG*FGWSFWP 201 G I S D +++++ K + Q F +F P Sbjct: 207 GTLIASAGKDGEIMLWNLAAKKAMYTLSAQDEVFSLAFSP 246 Score = 47.4 bits (111), Expect = 4e-05 Identities = 34/136 (25%), Positives = 65/136 (47%), Gaps = 7/136 (5%) Frame = -2 Query: 635 GQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLAR-QAIRSTCEHDEGVTCLA 459 G V S GH++ ++ +++ + + S D+TL +WD+A + + H V + Sbjct: 54 GVPVRSFKGHSHIVQDCTLTADGAYALSASWDKTLRLWDVATGETYQRFVGHKSDVMSVD 113 Query: 458 WLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAV----SADGNS--IVSVS 297 + + SG D +++W ++ G T GH D V + V AD +S I+S Sbjct: 114 IDKKASMIISGSRDKTIKVW-TIKGQCLATLLGHNDWVSQVRVVPNEKADDDSVTIISAG 172 Query: 296 TDKSARVFDISMFK*E 249 DK + ++++ F+ E Sbjct: 173 NDKMVKAWNLNQFQIE 188 Score = 46.6 bits (109), Expect = 7e-05 Identities = 33/135 (24%), Positives = 65/135 (48%), Gaps = 8/135 (5%) Frame = -2 Query: 647 SINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCEHDEGVT 468 ++N Q+ +GH ++I + S +A+ D +++W+LA + T + V Sbjct: 181 NLNQFQIEADFIGHNSNINTLTASPDGTLIASAGKDGEIMLWNLAAKKAMYTLSAQDEVF 240 Query: 467 CLAWLGSSRYVASGCIDGMVRIW----DSLSGDLARTFSGHRDVVQ----SLAVSADGNS 312 LA+ + ++A+ G ++++ L DL F+G+ + SLA SADG + Sbjct: 241 SLAFSPNRYWLAAATATG-IKVFSLDPQYLVDDLRPEFAGYSKAAEPHAVSLAWSADGQT 299 Query: 311 IVSVSTDKSARVFDI 267 + + TD RV+ + Sbjct: 300 LFAGYTDNVIRVWQV 314 Score = 40.4 bits (93), Expect = 0.005 Identities = 29/87 (33%), Positives = 43/87 (49%), Gaps = 7/87 (8%) Frame = -2 Query: 503 IRSTCE-HDEGVTCLAW-LGSSRYVASGCIDGMVRIW-----DSLSGDLARTFSGHRDVV 345 +R T E H+ VT LA G + S D + W D G R+F GH +V Sbjct: 8 LRGTLEGHNGWVTSLATSAGQPNLLLSASRDKTLISWKLTGDDQKFGVPVRSFKGHSHIV 67 Query: 344 QSLAVSADGNSIVSVSTDKSARVFDIS 264 Q ++ADG +S S DK+ R++D++ Sbjct: 68 QDCTLTADGAYALSASWDKTLRLWDVA 94
>GBB5_HUMAN (O14775) Guanine nucleotide-binding protein beta subunit 5| (Transducin beta chain 5) (Gbeta5) Length = 395 Score = 54.7 bits (130), Expect = 2e-07 Identities = 34/122 (27%), Positives = 57/122 (46%), Gaps = 4/122 (3%) Frame = -2 Query: 620 SLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDL-ARQAIRSTCEHDEGVTCLAWLGS- 447 S+ HTN + ++ + T S D T +WD+ + Q ++S H V CL S Sbjct: 190 SVAMHTNYLSACSFTNSDMQILTASGDGTCALWDVESGQLLQSFHGHGADVLCLDLAPSE 249 Query: 446 --SRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVF 273 + +V+ GC D +WD SG + F H + S+ G++ S S D + R++ Sbjct: 250 TGNTFVSGGC-DKKAMVWDMRSGQCVQAFETHESDINSVRYYPSGDAFASGSDDATCRLY 308 Query: 272 DI 267 D+ Sbjct: 309 DL 310 Score = 50.8 bits (120), Expect = 4e-06 Identities = 38/127 (29%), Positives = 58/127 (45%), Gaps = 3/127 (2%) Frame = -2 Query: 644 INSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQ---AIRSTCEHDEG 474 + SGQ V + H + I + + A+GS D T ++DL AI S G Sbjct: 268 MRSGQCVQAFETHESDINSVRYYPSGDAFASGSDDATCRLYDLRADREVAIYSKESIIFG 327 Query: 473 VTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVST 294 + + + S R + +G D + +WD L G GH + V +L VS DG + S S Sbjct: 328 ASSVDFSLSGRLLFAGYNDYTINVWDVLKGSRVSILFGHENRVSTLRVSPDGTAFCSGSW 387 Query: 293 DKSARVF 273 D + RV+ Sbjct: 388 DHTLRVW 394 Score = 43.9 bits (102), Expect = 4e-04 Identities = 27/80 (33%), Positives = 41/80 (51%), Gaps = 2/80 (2%) Frame = -2 Query: 500 RSTCEHDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGH-RDVV-QSLAVS 327 +S H ++ ++ S + + DG +WD SG L ++F GH DV+ LA S Sbjct: 189 KSVAMHTNYLSACSFTNSDMQILTASGDGTCALWDVESGQLLQSFHGHGADVLCLDLAPS 248 Query: 326 ADGNSIVSVSTDKSARVFDI 267 GN+ VS DK A V+D+ Sbjct: 249 ETGNTFVSGGCDKKAMVWDM 268 Score = 35.0 bits (79), Expect = 0.20 Identities = 20/79 (25%), Positives = 32/79 (40%) Frame = -2 Query: 485 HDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIV 306 H V C+ W R + S DG V +WDS + + + V + A + G +I Sbjct: 104 HGNKVLCMDWCKDKRRIVSSSQDGKVIVWDSFTTNKEHAVTMPCTWVMACAYAPSGCAIA 163 Query: 305 SVSTDKSARVFDISMFK*E 249 D V+ ++ K E Sbjct: 164 CGGLDNKCSVYPLTFDKNE 182 Score = 32.3 bits (72), Expect = 1.3 Identities = 18/66 (27%), Positives = 30/66 (45%) Frame = -2 Query: 620 SLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCEHDEGVTCLAWLGSSR 441 +L GH N + C+ + + S D +I+WD + + EH + C W+ + Sbjct: 100 TLKGHGNKVLCMDWCKDKRRIVSSSQDGKVIVWD----SFTTNKEHAVTMPC-TWVMACA 154 Query: 440 YVASGC 423 Y SGC Sbjct: 155 YAPSGC 160
>APAF_BRARE (Q9I9H8) Apoptotic protease-activating factor 1 (Apaf-1)| Length = 1261 Score = 53.9 bits (128), Expect = 4e-07 Identities = 35/138 (25%), Positives = 61/138 (44%), Gaps = 2/138 (1%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCEH 483 +V ++ + S + L GHT ++ + + T S D T+ +W H Sbjct: 989 TVQVIEVPSSKASVKLSGHTKTVHHCQFTDDCEILITSSEDSTIRVWKWRTGECMVLQGH 1048 Query: 482 DEGVTCLAWLGSSR--YVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSI 309 E V L SS ++ S DG V++WD G + + H V S VS+DG Sbjct: 1049 MEPVRKFHLLSSSSSPHLFSWSFDGTVKVWDLTRGQMLQDLVCHEGAVLSCDVSSDGRLF 1108 Query: 308 VSVSTDKSARVFDISMFK 255 + S +++A+V+ + +K Sbjct: 1109 ATTSANRTAKVWSSASWK 1126 Score = 42.0 bits (97), Expect = 0.002 Identities = 29/139 (20%), Positives = 57/139 (41%), Gaps = 6/139 (4%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAI--RSTC 489 ++ + SG+ + L H + C S +AT + DR + +W++ R + Sbjct: 640 ALRVFKSTSGEKLLELQAHEEDVLCCAFSPDDRHIATCASDRKVKLWNVERGVLIREFEV 699 Query: 488 EHDEGVTCLAWLGSSRYVASGCIDG----MVRIWDSLSGDLARTFSGHRDVVQSLAVSAD 321 EH+E + + + R V R+W+ T GH + V S + Sbjct: 700 EHEEQINHCQFTNTGRRVLLATCSNDKFTNTRLWNPNKKTSQNTMFGHMEPVNHCCFSPN 759 Query: 320 GNSIVSVSTDKSARVFDIS 264 + + S+D S ++F++S Sbjct: 760 DLYLATSSSDGSLKLFEVS 778 Score = 38.5 bits (88), Expect = 0.018 Identities = 23/95 (24%), Positives = 41/95 (43%), Gaps = 1/95 (1%) Frame = -2 Query: 548 SIDRTLIIWDLAR-QAIRSTCEHDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLAR 372 S D T+ +WDL R Q ++ H+ V R A+ + ++W S S + Sbjct: 1070 SFDGTVKVWDLTRGQMLQDLVCHEGAVLSCDVSSDGRLFATTSANRTAKVWSSASWKMLF 1129 Query: 371 TFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFDI 267 GH+D V+S S D + + + R++ + Sbjct: 1130 LLEGHKDCVRSCRFSWDNKRLATGDDNGEIRLWSM 1164 Score = 31.6 bits (70), Expect = 2.2 Identities = 28/122 (22%), Positives = 53/122 (43%), Gaps = 14/122 (11%) Frame = -2 Query: 617 LVGHTNSIECIGISSRYNW----VATGSIDRTLIIWDLARQAIRSTCEHDEG-------- 474 L GH + + S R++W +ATG + + +W + A+ C D Sbjct: 1131 LEGHKDCVR----SCRFSWDNKRLATGDDNGEIRLWSMLDGALLKICPRDTKDSMNSYHA 1186 Query: 473 --VTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSV 300 VT L + +R + S G ++ W SG+ +TF ++ + VS D ++ ++V Sbjct: 1187 GWVTDLHFSPDNRVLVSTA--GYIKWWSVESGEALQTFYTMGGNLKKIHVSPDFSTFITV 1244 Query: 299 ST 294 + Sbjct: 1245 DS 1246
>GBB2_CAEEL (Q20636) Guanine nucleotide-binding protein beta subunit 2| Length = 356 Score = 53.9 bits (128), Expect = 4e-07 Identities = 40/129 (31%), Positives = 58/129 (44%), Gaps = 5/129 (3%) Frame = -2 Query: 644 INSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCEHDEGVTC 465 I SGQ V S GH I + + ATGS D T ++DL +A R C +++ Sbjct: 229 IRSGQCVQSFEGHEADINTVRFHPNGDAFATGSDDATCRLFDL--RADRQVCVYEKESIL 286 Query: 464 LAWLG-----SSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSV 300 G S R + +G D V +WDSL GH + + L S DG ++ S Sbjct: 287 FPVNGVDFSLSGRILFAGYGDYRVGVWDSLKCARHSVLYGHENRISCLRTSPDGTAVCSA 346 Query: 299 STDKSARVF 273 S D + R++ Sbjct: 347 SWDCTIRIW 355 Score = 48.1 bits (113), Expect = 2e-05 Identities = 31/118 (26%), Positives = 57/118 (48%), Gaps = 4/118 (3%) Frame = -2 Query: 608 HTNSIECIGISSRYNWVATGSIDRTLIIWDL-ARQAIRSTCEHDEGVTCL---AWLGSSR 441 HT+ + C N + TGS D T IWD+ + Q I++ H V + + Sbjct: 155 HTSYMSCCTFLRSDNLILTGSGDSTCAIWDVESGQLIQNFHGHTGDVFAIDVPKCDTGNT 214 Query: 440 YVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFDI 267 ++++G D +WD SG ++F GH + ++ +G++ + S D + R+FD+ Sbjct: 215 FISAGA-DKHSLVWDIRSGQCVQSFEGHEADINTVRFHPNGDAFATGSDDATCRLFDL 271 Score = 47.8 bits (112), Expect = 3e-05 Identities = 33/120 (27%), Positives = 50/120 (41%), Gaps = 7/120 (5%) Frame = -2 Query: 605 TNSIECIGISSRYNWVATGSIDRTLIIWDLAR-----QAIRSTCEHDEGVTCLAWLGSSR 441 T + S +A G +D + L+ Q R H ++C +L S Sbjct: 110 TTWVMACAFSPSSQMIACGGLDNKCSVVPLSFEDDIIQKKRQVATHTSYMSCCTFLRSDN 169 Query: 440 YVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSA--DGNSIVSVSTDKSARVFDI 267 + +G D IWD SG L + F GH V ++ V GN+ +S DK + V+DI Sbjct: 170 LILTGSGDSTCAIWDVESGQLIQNFHGHTGDVFAIDVPKCDTGNTFISAGADKHSLVWDI 229 Score = 31.2 bits (69), Expect = 2.9 Identities = 18/74 (24%), Positives = 27/74 (36%) Frame = -2 Query: 485 HDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIV 306 H V C+ W R++ S DG V +WD + + + V + A S I Sbjct: 67 HVGKVLCMDWSLDKRHIVSSSQDGKVIVWDGFTTNKEHALTMPTTWVMACAFSPSSQMIA 126 Query: 305 SVSTDKSARVFDIS 264 D V +S Sbjct: 127 CGGLDNKCSVVPLS 140
>GBB3_MOUSE (Q61011) Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta| subunit 3 (Transducin beta chain 3) Length = 340 Score = 53.5 bits (127), Expect = 5e-07 Identities = 34/124 (27%), Positives = 55/124 (44%), Gaps = 2/124 (1%) Frame = -2 Query: 632 QVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCEHDEGVTCLAWL 453 +V L HT + C N + T S D T +WD+ ++ G C++ Sbjct: 134 KVSRELSAHTGYLSCCRFLDDNN-IVTSSGDTTCALWDIETGQQKTVFVGHTG-DCMSLA 191 Query: 452 GSSRY--VASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSAR 279 S Y SG D ++WD G +TF+GH + ++ +G +I + S D S R Sbjct: 192 VSPDYKLFISGACDASAKLWDVREGTCRQTFTGHESDINAICFFPNGEAICTGSDDASCR 251 Query: 278 VFDI 267 +FD+ Sbjct: 252 LFDL 255 Score = 51.6 bits (122), Expect = 2e-06 Identities = 34/134 (25%), Positives = 60/134 (44%), Gaps = 3/134 (2%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCEH 483 S + + G + GH + I I + TGS D + ++DL + Sbjct: 207 SAKLWDVREGTCRQTFTGHESDINAICFFPNGEAICTGSDDASCRLFDLRADQELTAYSQ 266 Query: 482 DE---GVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNS 312 + G+T +A+ S R + +G D +WDSL + SGH + V L V+ADG + Sbjct: 267 ESIICGITSVAFSLSGRLLFAGYDDFNCNVWDSLKCERVGILSGHDNRVSCLGVTADGMA 326 Query: 311 IVSVSTDKSARVFD 270 + + S D ++++ Sbjct: 327 VATGSWDSFLKIWN 340 Score = 37.0 bits (84), Expect = 0.053 Identities = 32/123 (26%), Positives = 55/123 (44%), Gaps = 5/123 (4%) Frame = -2 Query: 620 SLVGHTNSIECIGISSRYNWVATGSIDRTLIIWD-LARQAIRSTCEHDEGVTCLAWLGSS 444 +L GH I + ++ + + S D LI+WD + + V A+ S Sbjct: 50 TLRGHLAKIYAMHWATDSKLLVSASQDGKLIVWDTYTTNKVHAIPLRSSWVMTCAYAPSG 109 Query: 443 RYVASGCIDGMVRIWDSLSGD----LARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARV 276 +VA G +D M I++ S + ++R S H + S D N+IV+ S D + + Sbjct: 110 NFVACGGLDNMCSIYNLKSREGNVKVSRELSAHTGYL-SCCRFLDDNNIVTSSGDTTCAL 168 Query: 275 FDI 267 +DI Sbjct: 169 WDI 171
>GBB3_HUMAN (P16520) Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta| subunit 3 (Transducin beta chain 3) Length = 340 Score = 53.5 bits (127), Expect = 5e-07 Identities = 34/134 (25%), Positives = 60/134 (44%), Gaps = 3/134 (2%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCEH 483 S + + G + GH + I I + TGS D + ++DL H Sbjct: 207 SAKLWDVREGTCRQTFTGHESDINAICFFPNGEAICTGSDDASCRLFDLRADQELICFSH 266 Query: 482 DE---GVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNS 312 + G+T +A+ S R + +G D +WDS+ + SGH + V L V+ADG + Sbjct: 267 ESIICGITSVAFSLSGRLLFAGYDDFNCNVWDSMKSERVGILSGHDNRVSCLGVTADGMA 326 Query: 311 IVSVSTDKSARVFD 270 + + S D ++++ Sbjct: 327 VATGSWDSFLKIWN 340 Score = 52.8 bits (125), Expect = 9e-07 Identities = 33/123 (26%), Positives = 52/123 (42%), Gaps = 1/123 (0%) Frame = -2 Query: 632 QVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRST-CEHDEGVTCLAW 456 +V L HT + C N + T S D T +WD+ ++ H LA Sbjct: 134 KVSRELSAHTGYLSCCRFLDDNN-IVTSSGDTTCALWDIETGQQKTVFVGHTGDCMSLAV 192 Query: 455 LGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARV 276 SG D ++WD G +TF+GH + ++ +G +I + S D S R+ Sbjct: 193 SPDFNLFISGACDASAKLWDVREGTCRQTFTGHESDINAICFFPNGEAICTGSDDASCRL 252 Query: 275 FDI 267 FD+ Sbjct: 253 FDL 255 Score = 37.0 bits (84), Expect = 0.053 Identities = 32/123 (26%), Positives = 55/123 (44%), Gaps = 5/123 (4%) Frame = -2 Query: 620 SLVGHTNSIECIGISSRYNWVATGSIDRTLIIWD-LARQAIRSTCEHDEGVTCLAWLGSS 444 +L GH I + ++ + + S D LI+WD + + V A+ S Sbjct: 50 TLRGHLAKIYAMHWATDSKLLVSASQDGKLIVWDSYTTNKVHAIPLRSSWVMTCAYAPSG 109 Query: 443 RYVASGCIDGMVRIWDSLSGD----LARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARV 276 +VA G +D M I++ S + ++R S H + S D N+IV+ S D + + Sbjct: 110 NFVACGGLDNMCSIYNLKSREGNVKVSRELSAHTGYL-SCCRFLDDNNIVTSSGDTTCAL 168 Query: 275 FDI 267 +DI Sbjct: 169 WDI 171
>GBB1_DROME (P26308) Guanine nucleotide-binding protein beta subunit 1| Length = 340 Score = 53.5 bits (127), Expect = 5e-07 Identities = 34/134 (25%), Positives = 61/134 (45%), Gaps = 3/134 (2%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCEH 483 S + I G + GH + I + ATGS D T ++D+ + H Sbjct: 207 SAKLWDIREGVCKQTFPGHESDINAVTFFPNGQAFATGSDDATCRLFDIRADQELAMYSH 266 Query: 482 DE---GVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNS 312 D G+T +A+ S R + +G D +WD++ + + +GH + V L V+ +G + Sbjct: 267 DNIICGITSVAFSKSGRLLLAGYDDFNCNVWDTMKAERSGILAGHDNRVSCLGVTENGMA 326 Query: 311 IVSVSTDKSARVFD 270 + + S D RV++ Sbjct: 327 VATGSWDSFLRVWN 340 Score = 50.8 bits (120), Expect = 4e-06 Identities = 32/123 (26%), Positives = 52/123 (42%), Gaps = 1/123 (0%) Frame = -2 Query: 632 QVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQA-IRSTCEHDEGVTCLAW 456 +V L GH + C N + T S D + +WD+ + S H V L+ Sbjct: 134 RVSRELPGHGGYLSCCRFLDD-NQIVTSSGDMSCGLWDIETGLQVTSFLGHTGDVMALSL 192 Query: 455 LGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARV 276 + SG D ++WD G +TF GH + ++ +G + + S D + R+ Sbjct: 193 APQCKTFVSGACDASAKLWDIREGVCKQTFPGHESDINAVTFFPNGQAFATGSDDATCRL 252 Query: 275 FDI 267 FDI Sbjct: 253 FDI 255
>WD51B_MOUSE (Q8BHD1) WD-repeat protein 51B| Length = 476 Score = 53.5 bits (127), Expect = 5e-07 Identities = 40/123 (32%), Positives = 56/123 (45%), Gaps = 1/123 (0%) Frame = -2 Query: 620 SLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQA-IRSTCEHDEGVTCLAWLGSS 444 S GH +I S +AT S D L++W L A H + VT L + Sbjct: 13 SFKGHKAAITSADFSPNCKQIATASWDTFLMLWSLKPHARAYRYVGHKDVVTSLQFSPQG 72 Query: 443 RYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFDIS 264 +AS D VR+W + F H V+S+ SADG +V+ S DKS +V+ S Sbjct: 73 NLLASASRDRTVRLWVLDRKGKSSEFKAHTAPVRSVDFSADGQLLVTASEDKSIKVW--S 130 Query: 263 MFK 255 MF+ Sbjct: 131 MFR 133 Score = 52.4 bits (124), Expect = 1e-06 Identities = 29/119 (24%), Positives = 53/119 (44%), Gaps = 1/119 (0%) Frame = -2 Query: 608 HTNSIECIGISSRYNWVATGSIDRTLIIWDLARQA-IRSTCEHDEGVTCLAWLGSSRYVA 432 HT + + S+ + T S D+++ +W + RQ + S H V C + R + Sbjct: 101 HTAPVRSVDFSADGQLLVTASEDKSIKVWSMFRQRFLYSLYRHTHWVRCAKFSPDGRLIV 160 Query: 431 SGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFDISMFK 255 S D ++IWD+ + FS + + +G I S +D + +++DI M K Sbjct: 161 SCSEDKTIKIWDTTNKQCVNNFSDSVGFANFVDFNPNGTCIASAGSDHAVKIWDIRMNK 219 Score = 49.3 bits (116), Expect = 1e-05 Identities = 33/133 (24%), Positives = 63/133 (47%), Gaps = 1/133 (0%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLA-RQAIRSTCE 486 S+ + S+ + + SL HT+ + C S + + S D+T+ IWD +Q + + + Sbjct: 125 SIKVWSMFRQRFLYSLYRHTHWVRCAKFSPDGRLIVSCSEDKTIKIWDTTNKQCVNNFSD 184 Query: 485 HDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIV 306 + + + +AS D V+IWD L + + H V L+ GNS+V Sbjct: 185 SVGFANFVDFNPNGTCIASAGSDHAVKIWDIRMNKLLQHYQVHSCGVNCLSFHPLGNSLV 244 Query: 305 SVSTDKSARVFDI 267 + S+D + ++ D+ Sbjct: 245 TASSDGTVKMLDL 257 Score = 45.8 bits (107), Expect = 1e-04 Identities = 30/99 (30%), Positives = 48/99 (48%), Gaps = 3/99 (3%) Frame = -2 Query: 560 VATGSIDRTLIIWDLARQAIRSTCE-HDEGVTCLAW--LGSSRYVASGCIDGMVRIWDSL 390 +A+ D + IWD+ + + H GV CL++ LG+S AS DG V++ D + Sbjct: 201 IASAGSDHAVKIWDIRMNKLLQHYQVHSCGVNCLSFHPLGNSLVTASS--DGTVKMLDLI 258 Query: 389 SGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVF 273 G L T GH V +++ S DG + S D ++ Sbjct: 259 EGRLIYTLQGHTGPVFTVSFSKDGELLTSGGADAQVLIW 297 Score = 41.2 bits (95), Expect = 0.003 Identities = 22/76 (28%), Positives = 37/76 (48%) Frame = -2 Query: 500 RSTCEHDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSAD 321 RS H +T + + + +A+ D + +W A + GH+DVV SL S Sbjct: 12 RSFKGHKAAITSADFSPNCKQIATASWDTFLMLWSLKPHARAYRYVGHKDVVTSLQFSPQ 71 Query: 320 GNSIVSVSTDKSARVF 273 GN + S S D++ R++ Sbjct: 72 GNLLASASRDRTVRLW 87
>WDR39_HUMAN (O76071) WD-repeat protein 39 (Ciao 1 protein)| Length = 339 Score = 53.5 bits (127), Expect = 5e-07 Identities = 32/126 (25%), Positives = 58/126 (46%), Gaps = 6/126 (4%) Frame = -2 Query: 632 QVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQ----AIRSTCEHDEGVTC 465 + V +L GH N ++ + + N +AT S D+++ +W++ + + H + V Sbjct: 96 ECVTTLEGHENEVKSVAWAPSGNLLATCSRDKSVWVWEVDEEDEYECVSVLNSHTQDVKH 155 Query: 464 LAWLGSSRYVASGCIDGMVRIWDSLSGD--LARTFSGHRDVVQSLAVSADGNSIVSVSTD 291 + W S +AS D V+++ D T GH V SLA G + S S D Sbjct: 156 VVWHPSQELLASASYDDTVKLYREEEDDWVCCATLEGHESTVWSLAFDPSGQRLASCSDD 215 Query: 290 KSARVF 273 ++ R++ Sbjct: 216 RTVRIW 221 Score = 43.9 bits (102), Expect = 4e-04 Identities = 24/75 (32%), Positives = 35/75 (46%), Gaps = 2/75 (2%) Frame = -2 Query: 485 HDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDL--ARTFSGHRDVVQSLAVSADGNS 312 H V +AW Y+AS D IW D T GH + V+S+A + GN Sbjct: 60 HQRTVRKVAWSPCGNYLASASFDATTCIWKKNQDDFECVTTLEGHENEVKSVAWAPSGNL 119 Query: 311 IVSVSTDKSARVFDI 267 + + S DKS V+++ Sbjct: 120 LATCSRDKSVWVWEV 134 Score = 35.4 bits (80), Expect = 0.15 Identities = 25/119 (21%), Positives = 49/119 (41%), Gaps = 6/119 (5%) Frame = -2 Query: 611 GHTNSIECIGISSRYNWVATGSIDRTLIIWDLAR---QAIRSTCEHDEGVTCLAWLGSSR 441 GH ++ + S N++A+ S D T IW + + + + H+ V +AW S Sbjct: 59 GHQRTVRKVAWSPCGNYLASASFDATTCIWKKNQDDFECVTTLEGHENEVKSVAWAPSGN 118 Query: 440 YVASGCIDGMVRIWDSLSGD---LARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVF 273 +A+ D V +W+ D + H V+ + + S S D + +++ Sbjct: 119 LLATCSRDKSVWVWEVDEEDEYECVSVLNSHTQDVKHVVWHPSQELLASASYDDTVKLY 177
>PRP4_ARATH (O22212) U4/U6 small nuclear ribonucleoprotein PRP4-like protein| Length = 554 Score = 53.5 bits (127), Expect = 5e-07 Identities = 34/128 (26%), Positives = 57/128 (44%), Gaps = 1/128 (0%) Frame = -2 Query: 635 GQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCE-HDEGVTCLA 459 G ++ + GH + + + ++ T S D+T +WD+ A E H V +A Sbjct: 329 GTLLQTFEGHLDRLARVAFHPSGKYLGTTSYDKTWRLWDINTGAELLLQEGHSRSVYGIA 388 Query: 458 WLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSAR 279 + AS +D + R+WD +G F GH V S+ S +G + S D R Sbjct: 389 FQQDGALAASCGLDSLARVWDLRTGRSILVFQGHIKPVFSVNFSPNGYHLASGGEDNQCR 448 Query: 278 VFDISMFK 255 ++D+ M K Sbjct: 449 IWDLRMRK 456 Score = 49.3 bits (116), Expect = 1e-05 Identities = 33/129 (25%), Positives = 61/129 (47%), Gaps = 2/129 (1%) Frame = -2 Query: 644 INSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLA-RQAIRSTCEHDEGVT 468 + +G+ + GH + + S +A+G D IWDL R+++ H V+ Sbjct: 410 LRTGRSILVFQGHIKPVFSVNFSPNGYHLASGGEDNQCRIWDLRMRKSLYIIPAHANLVS 469 Query: 467 CLAWLGSSRY-VASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTD 291 + + Y +A+ D V IW L ++ +GH V SL ++AD + I +VS D Sbjct: 470 QVKYEPQEGYFLATASYDMKVNIWSGRDFSLVKSLAGHESKVASLDITADSSCIATVSHD 529 Query: 290 KSARVFDIS 264 ++ +++ S Sbjct: 530 RTIKLWTSS 538 Score = 45.1 bits (105), Expect = 2e-04 Identities = 28/98 (28%), Positives = 45/98 (45%) Frame = -2 Query: 560 VATGSIDRTLIIWDLARQAIRSTCEHDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGD 381 +AT S DRT +W +++ H + + +A+ S +Y+ + D R+WD +G Sbjct: 313 LATASADRTAKLWKTDGTLLQTFEGHLDRLARVAFHPSGKYLGTTSYDKTWRLWDINTGA 372 Query: 380 LARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFDI 267 GH V +A DG S D ARV+D+ Sbjct: 373 ELLLQEGHSRSVYGIAFQQDGALAASCGLDSLARVWDL 410 Score = 31.2 bits (69), Expect = 2.9 Identities = 16/46 (34%), Positives = 27/46 (58%) Frame = -2 Query: 659 VHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIW 522 V+I S +V SL GH + + + I++ + +AT S DRT+ +W Sbjct: 490 VNIWSGRDFSLVKSLAGHESKVASLDITADSSCIATVSHDRTIKLW 535
>GBB_LOLFO (P23232) Guanine nucleotide-binding protein beta subunit| Length = 341 Score = 53.1 bits (126), Expect = 7e-07 Identities = 36/134 (26%), Positives = 58/134 (43%), Gaps = 3/134 (2%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCEH 483 S + I G + GH + I I ATGS D T ++D+ H Sbjct: 208 SAKLFDIRDGICKQTFTGHESDINAITYFPNGFAFATGSDDATCRLFDIRADQEIGMYSH 267 Query: 482 DE---GVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNS 312 D G+T +A+ S R + G D +WD L + A +GH + V L V+ DG + Sbjct: 268 DNIICGITSVAFSKSGRLLLGGYDDFNCNVWDVLKQERAGVLAGHDNRVSCLGVTEDGMA 327 Query: 311 IVSVSTDKSARVFD 270 + + S D ++++ Sbjct: 328 VATGSWDSFLKIWN 341 Score = 52.0 bits (123), Expect = 2e-06 Identities = 37/135 (27%), Positives = 59/135 (43%), Gaps = 3/135 (2%) Frame = -2 Query: 662 SVHIVSINSGQVVGS--LVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLAR-QAIRST 492 S++ + G V S L GHT + C N + T S D T +W++ I S Sbjct: 123 SIYSLKTREGNVRVSRELPGHTGYLSCCRFIDD-NQIVTSSGDMTCALWNIETGNQITSF 181 Query: 491 CEHDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNS 312 H V L+ R SG D +++D G +TF+GH + ++ +G + Sbjct: 182 GGHTGDVMSLSLAPDMRTFVSGACDASAKLFDIRDGICKQTFTGHESDINAITYFPNGFA 241 Query: 311 IVSVSTDKSARVFDI 267 + S D + R+FDI Sbjct: 242 FATGSDDATCRLFDI 256 Score = 37.7 bits (86), Expect = 0.031 Identities = 39/164 (23%), Positives = 61/164 (37%), Gaps = 46/164 (28%) Frame = -2 Query: 620 SLVGHTNSIECIGISSRYNWVATGSIDRTLIIWD-LARQAIRSTCEHDEGVTCLAWLGSS 444 +L GH I + +S + + S D LI+WD + + V A+ S Sbjct: 51 TLRGHLAKIYAMHWASDSRNLVSASQDGKLIVWDGYTTNKVHAIPLRSSWVMTCAYAPSG 110 Query: 443 RYVASGCID------------GMVRI---------------------------------W 399 YVA G +D G VR+ W Sbjct: 111 NYVACGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFIDDNQIVTSSGDMTCALW 170 Query: 398 DSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFDI 267 + +G+ +F GH V SL+++ D + VS + D SA++FDI Sbjct: 171 NIETGNQITSFGGHTGDVMSLSLAPDMRTFVSGACDASAKLFDI 214 Score = 30.0 bits (66), Expect = 6.5 Identities = 19/98 (19%), Positives = 38/98 (38%) Frame = -2 Query: 560 VATGSIDRTLIIWDLARQAIRSTCEHDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGD 381 +AT +++ I R+ +R H + + W SR + S DG + +WD + + Sbjct: 33 MATANVEPVGRIQMRTRRTLRG---HLAKIYAMHWASDSRNLVSASQDGKLIVWDGYTTN 89 Query: 380 LARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFDI 267 V + A + GN + D ++ + Sbjct: 90 KVHAIPLRSSWVMTCAYAPSGNYVACGGLDNICSIYSL 127
>WDR1_HUMAN (O75083) WD-repeat protein 1 (Actin-interacting protein 1) (AIP1)| (NORI-1) Length = 605 Score = 53.1 bits (126), Expect = 7e-07 Identities = 35/132 (26%), Positives = 63/132 (47%), Gaps = 5/132 (3%) Frame = -2 Query: 641 NSGQVVGSLVGHTNSIECIGIS-SRYNWVATGSIDRTLIIWDLARQAIRSTC-EHDEGVT 468 +SG VG + GH I + I SR +ATGS D ++ + T +H V Sbjct: 133 DSGSSVGEITGHNKVINSVDIKQSRPYRLATGSDDNCAAFFEGPPFKFKFTIGDHSRFVN 192 Query: 467 CLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSG---HRDVVQSLAVSADGNSIVSVS 297 C+ + A+ DG + I+D +G+ G H + +++ S D ++S S Sbjct: 193 CVRFSPDGNRFATASADGQIYIYDGKTGEKVCALGGSKAHDGGIYAISWSPDSTHLLSAS 252 Query: 296 TDKSARVFDISM 261 DK+++++D+S+ Sbjct: 253 GDKTSKIWDVSV 264 Score = 39.3 bits (90), Expect = 0.011 Identities = 29/109 (26%), Positives = 47/109 (43%), Gaps = 5/109 (4%) Frame = -2 Query: 608 HTNSIECIGISSRYNWVATGSIDRTLIIWDLARQ----AIRSTCEHDEGVTCLAWLGSSR 441 H+ + C+ S N AT S D + I+D A+ + HD G+ ++W S Sbjct: 187 HSRFVNCVRFSPDGNRFATASADGQIYIYDGKTGEKVCALGGSKAHDGGIYAISWSPDST 246 Query: 440 YVASGCIDGMVRIWDSLSGDLARTF-SGHRDVVQSLAVSADGNSIVSVS 297 ++ S D +IWD + TF G + Q L + ++SVS Sbjct: 247 HLLSASGDKTSKIWDVSVNSVVSTFPMGSTVLDQQLGCLWQKDHLLSVS 295 Score = 34.3 bits (77), Expect = 0.34 Identities = 24/76 (31%), Positives = 37/76 (48%), Gaps = 2/76 (2%) Frame = -2 Query: 485 HDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLART--FSGHRDVVQSLAVSADGNS 312 H + CLAW + + ASG +D MV +W +LS R HR S D ++ Sbjct: 530 HHAKIVCLAWSPDNEHFASGGMDMMVYVW-TLSDPETRVKIQDAHRLHHVSSLAWLDEHT 588 Query: 311 IVSVSTDKSARVFDIS 264 +V+ S D S + + I+ Sbjct: 589 LVTTSHDASVKEWTIT 604 Score = 30.8 bits (68), Expect = 3.8 Identities = 20/76 (26%), Positives = 34/76 (44%), Gaps = 4/76 (5%) Frame = -2 Query: 488 EHDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGD--LARTFSGHRDVVQSLAVSADGN 315 EH V + S Y+ASG + G +RIWD+ + L + ++ +A + D Sbjct: 55 EHAHQVVVAKYAPSGFYIASGDVSGKLRIWDTTQKEHLLKYEYQPFAGKIKDIAWTEDSK 114 Query: 314 --SIVSVSTDKSARVF 273 ++V +K VF Sbjct: 115 RIAVVGEGREKFGAVF 130
>MORG1_XENTR (Q5XGI5) Mitogen-activated protein kinase organizer 1 (MAPK| organizer 1) Length = 314 Score = 53.1 bits (126), Expect = 7e-07 Identities = 32/134 (23%), Positives = 64/134 (47%), Gaps = 3/134 (2%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLAR---QAIRST 492 +V + + GQVV GH + C+ + + +GSID ++ WD +AI+ Sbjct: 90 TVILWDVAQGQVVRKFRGHAGKVNCVQFNEEATVIMSGSIDSSIRCWDCRSRRPEAIQIL 149 Query: 491 CEHDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNS 312 E +G++ + S + +G +DG +R +D G++ + G + ++ S D Sbjct: 150 DEAKDGISSIKI--SDHEILAGSVDGNLRRYDLRKGEMCADYLG--SPITCVSFSQDSQC 205 Query: 311 IVSVSTDKSARVFD 270 +++ S D + R+ D Sbjct: 206 LLASSLDSTLRLLD 219 Score = 40.8 bits (94), Expect = 0.004 Identities = 28/100 (28%), Positives = 43/100 (43%), Gaps = 1/100 (1%) Frame = -2 Query: 566 NWVATGSIDRTLIIWDLARQAIRSTCE-HDEGVTCLAWLGSSRYVASGCIDGMVRIWDSL 390 N+ T D+TL +W+ + + T H V A + + S D V +WD Sbjct: 38 NYCMTCGSDKTLKLWNPHKGTLLKTYSGHGYEVLDTAGSYDNSQMCSCSSDKTVILWDVA 97 Query: 389 SGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFD 270 G + R F GH V + + + I+S S D S R +D Sbjct: 98 QGQVVRKFRGHAGKVNCVQFNEEATVIMSGSIDSSIRCWD 137 Score = 37.4 bits (85), Expect = 0.040 Identities = 17/52 (32%), Positives = 31/52 (59%) Frame = -2 Query: 419 DGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFDIS 264 D +++W+ G L +T+SGH V A S D + + S S+DK+ ++D++ Sbjct: 46 DKTLKLWNPHKGTLLKTYSGHGYEVLDTAGSYDNSQMCSCSSDKTVILWDVA 97
>PFS2_YEAST (P42841) Protein PFS2| Length = 465 Score = 53.1 bits (126), Expect = 7e-07 Identities = 36/116 (31%), Positives = 55/116 (47%), Gaps = 2/116 (1%) Frame = -2 Query: 608 HTNSIECIGISSRYNWVATGSIDRTLIIWDLAR-QAIRSTCEHDEGVTCLAWLGSSRYVA 432 HT SI + SS + T S D L IW+ + + R H V W +A Sbjct: 176 HTESIRDMAFSSNDSKFVTCSDDNILKIWNFSNGKQERVLSGHHWDVKSCDWHPEMGLIA 235 Query: 431 SGCIDGMVRIWDSLSGD-LARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFDI 267 S D +V++WD SG+ ++ V+++ GN ++++S DKS RVFDI Sbjct: 236 SASKDNLVKLWDPRSGNCISSILKFKHTVLKTRFQPTKGNLLMAISKDKSCRVFDI 291 Score = 45.8 bits (107), Expect = 1e-04 Identities = 26/98 (26%), Positives = 47/98 (47%) Frame = -2 Query: 485 HDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIV 306 HD VT + + S ++ SG DGM++IW + + H + ++ +A S++ + V Sbjct: 134 HDSAVTTMKYSHDSDWMISGDADGMIKIWQPNFSMVKEIDAAHTESIRDMAFSSNDSKFV 193 Query: 305 SVSTDKSARVFDISMFK*EKS*QQQHG*FGWSFWPVKS 192 + S D ++++ S K E+ H W VKS Sbjct: 194 TCSDDNILKIWNFSNGKQERVLSGHH-------WDVKS 224 Score = 41.2 bits (95), Expect = 0.003 Identities = 25/114 (21%), Positives = 50/114 (43%), Gaps = 1/114 (0%) Frame = -2 Query: 608 HTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRST-CEHDEGVTCLAWLGSSRYVA 432 H +++ + S +W+ +G D + IW ++ H E + +A+ + Sbjct: 134 HDSAVTTMKYSHDSDWMISGDADGMIKIWQPNFSMVKEIDAAHTESIRDMAFSSNDSKFV 193 Query: 431 SGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFD 270 + D +++IW+ +G R SGH V+S + I S S D +++D Sbjct: 194 TCSDDNILKIWNFSNGKQERVLSGHHWDVKSCDWHPEMGLIASASKDNLVKLWD 247
>KMHB_DICDI (P90648) Myosin heavy chain kinase B (EC 2.7.11.7) (MHCK B)| Length = 732 Score = 52.8 bits (125), Expect = 9e-07 Identities = 35/133 (26%), Positives = 67/133 (50%), Gaps = 1/133 (0%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCE- 486 S+ + + + + +L GH + + ++ +Y + +GS D+T+ +WDL + T E Sbjct: 523 SIKVWDLKKLRCIFTLEGHDKPVHTVLLNDKY--LFSGSSDKTIKVWDLKTLECKYTLES 580 Query: 485 HDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIV 306 H V L G +Y+ SG D +++WD + T GH V ++ + G ++ Sbjct: 581 HARAVKTLCISG--QYLFSGSNDKTIKVWDLKTFRCNYTLKGHTKWVTTICIL--GTNLY 636 Query: 305 SVSTDKSARVFDI 267 S S DK+ RV+++ Sbjct: 637 SGSYDKTIRVWNL 649 Score = 50.4 bits (119), Expect = 5e-06 Identities = 37/117 (31%), Positives = 55/117 (47%), Gaps = 1/117 (0%) Frame = -2 Query: 620 SLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCE-HDEGVTCLAWLGSS 444 +L GHT + I I + +GS D+T+ +W+L +T HD V + Sbjct: 617 TLKGHTKWVTTICILGTNLY--SGSYDKTIRVWNLKSLECSATLRGHDRWVEHMVICDKL 674 Query: 443 RYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVF 273 + AS D ++IWD + T GH VQ LAV D ++S S D+S RV+ Sbjct: 675 LFTASD--DNTIKIWDLETLRCNTTLEGHNATVQCLAVWEDKKCVISCSHDQSIRVW 729 Score = 35.4 bits (80), Expect = 0.15 Identities = 25/103 (24%), Positives = 50/103 (48%), Gaps = 3/103 (2%) Frame = -2 Query: 566 NWVATGSIDRTLIIWDLARQ---AIRSTCEHDEGVTCLAWLGSSRYVASGCIDGMVRIWD 396 N + TG D ++ ++D Q +++ H+ V + + + +Y+ SG D +++WD Sbjct: 471 NLLFTGCSDNSIRVYDYKSQNMECVQTLKGHEGPVESICY--NDQYLFSGSSDHSIKVWD 528 Query: 395 SLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFDI 267 T GH V + V + + S S+DK+ +V+D+ Sbjct: 529 LKKLRCIFTLEGHDKPVHT--VLLNDKYLFSGSSDKTIKVWDL 569
>MORG1_XENLA (Q3KQ62) Mitogen-activated protein kinase organizer 1 (MAPK| organizer 1) Length = 314 Score = 52.8 bits (125), Expect = 9e-07 Identities = 32/134 (23%), Positives = 65/134 (48%), Gaps = 3/134 (2%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQ---AIRST 492 +V + + GQVV GH + C+ + + +GSID ++ WD + AI+ Sbjct: 90 TVILWDVAQGQVVRKFRGHAGKVNCVQFNEEATVIISGSIDSSIRCWDCRSRRPDAIQIM 149 Query: 491 CEHDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNS 312 E +G++ + S+ + +G +DG +R +D G++ + G + ++ S D Sbjct: 150 DEAKDGISSVK--VSAHEILAGSVDGNLRRYDLRKGEMCADYLG--SPITCVSFSQDSQC 205 Query: 311 IVSVSTDKSARVFD 270 +++ S D + R+ D Sbjct: 206 LLASSLDSTLRLLD 219 Score = 50.8 bits (120), Expect = 4e-06 Identities = 36/135 (26%), Positives = 68/135 (50%), Gaps = 3/135 (2%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLAR-QAIRSTCE 486 S+ + + + G ++ + GH + S + + + S D+T+I+WD+A+ Q +R Sbjct: 48 SLKLWNPHKGSLLKTYSGHGYEVLDTAGSCDNSQLCSCSSDKTVILWDVAQGQVVRKFRG 107 Query: 485 HDEGVTCLAWLGSSRYVASGCIDGMVRIWD--SLSGDLARTFSGHRDVVQSLAVSADGNS 312 H V C+ + + + SG ID +R WD S D + +D + S+ VSA + Sbjct: 108 HAGKVNCVQFNEEATVIISGSIDSSIRCWDCRSRRPDAIQIMDEAKDGISSVKVSA--HE 165 Query: 311 IVSVSTDKSARVFDI 267 I++ S D + R +D+ Sbjct: 166 ILAGSVDGNLRRYDL 180 Score = 40.4 bits (93), Expect = 0.005 Identities = 27/100 (27%), Positives = 44/100 (44%), Gaps = 1/100 (1%) Frame = -2 Query: 566 NWVATGSIDRTLIIWDLARQAIRSTCE-HDEGVTCLAWLGSSRYVASGCIDGMVRIWDSL 390 N+ T D++L +W+ + ++ T H V A + + S D V +WD Sbjct: 38 NYCMTCGSDKSLKLWNPHKGSLLKTYSGHGYEVLDTAGSCDNSQLCSCSSDKTVILWDVA 97 Query: 389 SGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFD 270 G + R F GH V + + + I+S S D S R +D Sbjct: 98 QGQVVRKFRGHAGKVNCVQFNEEATVIISGSIDSSIRCWD 137 Score = 38.9 bits (89), Expect = 0.014 Identities = 17/52 (32%), Positives = 31/52 (59%) Frame = -2 Query: 419 DGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFDIS 264 D +++W+ G L +T+SGH V A S D + + S S+DK+ ++D++ Sbjct: 46 DKSLKLWNPHKGSLLKTYSGHGYEVLDTAGSCDNSQLCSCSSDKTVILWDVA 97
>PLAP_MOUSE (P27612) Phospholipase A-2-activating protein (PLAP)| Length = 646 Score = 52.8 bits (125), Expect = 9e-07 Identities = 31/116 (26%), Positives = 60/116 (51%) Frame = -2 Query: 620 SLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCEHDEGVTCLAWLGSSR 441 +L GHT ++ + I + TGS D+T+ +W R R+ H++ V LA L + Sbjct: 89 TLQGHTAAVWAVKILPEQGLMLTGSADKTIKLWKAGR-CERTFLGHEDCVRGLAILSETE 147 Query: 440 YVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVF 273 ++ S D +R W ++G+ + GH + + S++V + V+ + D+S R++ Sbjct: 148 FL-SCANDASIRRW-QITGECLEVYFGHTNYIYSISVFPNSKDFVTTAEDRSLRIW 201
>YAGE_SCHPO (Q9UTN4) Hypothetical WD-repeat protein C12G12.14c in chromosome I| Length = 509 Score = 52.8 bits (125), Expect = 9e-07 Identities = 33/122 (27%), Positives = 57/122 (46%), Gaps = 4/122 (3%) Frame = -2 Query: 608 HTNSIECIGISSRYNWVATGSIDRTLIIWD--LARQAIRSTCEHDEGVTCLAWLGSSRYV 435 H + + S + T S D +L +W+ ++ + ++ T H V + W S + Sbjct: 163 HEMEVRDVAFSPNDSKFVTASDDGSLKVWNFHMSTEELKLT-GHGWDVKTVDWHPSKGLL 221 Query: 434 ASGCIDGMVRIWDSLSGDLARTFSGHRDVVQ--SLAVSADGNSIVSVSTDKSARVFDISM 261 ASG D +V+ WD +G T GH++ + S + N + +VS D + RVFD+ Sbjct: 222 ASGSKDNLVKFWDPRTGTCIATLHGHKNTIMQASFQKNFGSNYLATVSRDSTCRVFDLRA 281 Query: 260 FK 255 K Sbjct: 282 MK 283 Score = 37.0 bits (84), Expect = 0.053 Identities = 21/75 (28%), Positives = 37/75 (49%) Frame = -2 Query: 485 HDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIV 306 HD V C W R++ SG GMV+ ++ ++ + H V+ +A S + + V Sbjct: 122 HDYAVRCAEWSTDGRWLISGDGGGMVKYFEPNLNNV-KIVQAHEMEVRDVAFSPNDSKFV 180 Query: 305 SVSTDKSARVFDISM 261 + S D S +V++ M Sbjct: 181 TASDDGSLKVWNFHM 195
>TEP1_MOUSE (P97499) Telomerase protein component 1 (Telomerase-associated| protein 1) (Telomerase protein 1) (p240) (p80 homolog) Length = 2629 Score = 52.4 bits (124), Expect = 1e-06 Identities = 42/122 (34%), Positives = 57/122 (46%), Gaps = 6/122 (4%) Frame = -2 Query: 617 LVGHTNSIECIGISSRYNWVATGSIDRTLIIWDL-ARQA-----IRSTCEHDEGVTCLAW 456 L GH + C S +AT DR L+ WD+ QA S+C H + +T AW Sbjct: 2065 LRGHEGPVCCCSFSPDGGILATAGRDRNLLCWDMKIAQAPLLIHTFSSC-HRDWITGCAW 2123 Query: 455 LGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARV 276 + S DG V +W+ +G FSGH+ V AV A IVSVS D + +V Sbjct: 2124 T-KDNILVSCSSDGSVGLWNPEAGQQLGQFSGHQSAVS--AVVAVEEHIVSVSRDGTLKV 2180 Query: 275 FD 270 +D Sbjct: 2181 WD 2182 Score = 44.3 bits (103), Expect = 3e-04 Identities = 36/141 (25%), Positives = 63/141 (44%), Gaps = 9/141 (6%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCEH 483 SV + + +GQ +G GH +++ + + + + S D TL +WD + S H Sbjct: 2137 SVGLWNPEAGQQLGQFSGHQSAVSAVVAVEEH--IVSVSRDGTLKVWDHQGVELTSIPAH 2194 Query: 482 DEGVT-CLAWL--------GSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAV 330 ++ C A L GS V + +DG ++W L RT GH V + A Sbjct: 2195 SGPISQCAAALEPRPGGQPGSELLVVTVGLDGATKLWHPLLVCQIRTLQGHSGPVTAAAA 2254 Query: 329 SADGNSIVSVSTDKSARVFDI 267 S + + ++ S D S +++ I Sbjct: 2255 S-EASGLLLTSDDSSVQLWQI 2274 Score = 31.6 bits (70), Expect = 2.2 Identities = 25/113 (22%), Positives = 43/113 (38%), Gaps = 1/113 (0%) Frame = -2 Query: 608 HTNSIECIGISSRYNWVATGSIDRTLIIWDL-ARQAIRSTCEHDEGVTCLAWLGSSRYVA 432 H S+ C+ VATGS ++ + + + V LA+ + VA Sbjct: 1806 HPKSLNCVAFHPEGQVVATGSWAGSITFFQADGLKVTKELGAPGPSVCSLAFNKPGKIVA 1865 Query: 431 SGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVF 273 G IDG V +W G F V ++ G+ ++ D A+++ Sbjct: 1866 VGRIDGTVELWAWQEGARLAAFPAQCGCVSAVLFLHAGDRFLTAGEDGKAQLW 1918
>WDR18_RAT (Q499N3) WD-repeat protein 18| Length = 431 Score = 52.0 bits (123), Expect = 2e-06 Identities = 32/110 (29%), Positives = 56/110 (50%), Gaps = 12/110 (10%) Frame = -2 Query: 560 VATGSIDRTLIIWDLARQAIRSTCEHDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSG- 384 VAT S+D+T+ +W ++ + + D G+T + + Y+ G DG + D S Sbjct: 189 VATASLDQTMKLWAISSGDLLLSVLFDMGITSVTMDLAEHYIFCGGSDGSIFQVDLCSRP 248 Query: 383 -----------DLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFDI 267 + + F GHR+ V L+VS DG+ ++S S D+S R++D+ Sbjct: 249 GPREQSFQPEQNTGKVFKGHRNQVTCLSVSTDGSILLSGSHDESVRLWDV 298 Score = 33.9 bits (76), Expect = 0.45 Identities = 19/61 (31%), Positives = 29/61 (47%) Frame = -2 Query: 473 VTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVST 294 VTCL + YV +G + + +W+ +G+L S H V L + DG+ VS Sbjct: 83 VTCLTTAPNGLYVLAGIAES-IYLWEVSTGNLLVILSRHYQDVSCLKFTGDGSHFVSAGK 141 Query: 293 D 291 D Sbjct: 142 D 142 Score = 32.7 bits (73), Expect = 1.00 Identities = 15/50 (30%), Positives = 32/50 (64%), Gaps = 1/50 (2%) Frame = -2 Query: 641 NSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDL-ARQAIRS 495 N+G+V GH N + C+ +S+ + + +GS D ++ +WD+ ++Q +R+ Sbjct: 260 NTGKV---FKGHRNQVTCLSVSTDGSILLSGSHDESVRLWDVKSKQCVRT 306
>GBB_CRYPA (O14435) Guanine nucleotide-binding protein beta subunit| Length = 359 Score = 52.0 bits (123), Expect = 2e-06 Identities = 33/124 (26%), Positives = 59/124 (47%), Gaps = 2/124 (1%) Frame = -2 Query: 632 QVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIR-STCEHDEGVTCLAW 456 +V L GH + C + + + T S D T + WD+ + +H V ++ Sbjct: 151 RVARELSGHAGYLSCCRFINDRS-ILTSSGDMTCMKWDIETGTKQIEFADHLGDVMSISL 209 Query: 455 LGSSRYV-ASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSAR 279 +++ SG D ++WD +G +TF+GH + ++ DG+S V+ S D + R Sbjct: 210 NPTNQNTFISGACDAFAKLWDIRAGKAVQTFAGHESDINAIQFFPDGHSFVTGSDDATCR 269 Query: 278 VFDI 267 +FDI Sbjct: 270 LFDI 273 Score = 50.1 bits (118), Expect = 6e-06 Identities = 34/127 (26%), Positives = 58/127 (45%), Gaps = 3/127 (2%) Frame = -2 Query: 644 INSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCEHDE---G 474 I +G+ V + GH + I I + TGS D T ++D+ + + G Sbjct: 231 IRAGKAVQTFAGHESDINAIQFFPDGHSFVTGSDDATCRLFDIRADRELNVYGSESILCG 290 Query: 473 VTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVST 294 +T +A S R + +G D ++WD G+ + GH + V L VS DG S+ + S Sbjct: 291 ITSVATSVSGRLLFAGYDDFECKVWDVTRGEKVGSLVGHENRVSCLGVSNDGISLCTGSW 350 Query: 293 DKSARVF 273 D +++ Sbjct: 351 DSLLKIW 357 Score = 34.3 bits (77), Expect = 0.34 Identities = 33/124 (26%), Positives = 51/124 (41%), Gaps = 6/124 (4%) Frame = -2 Query: 620 SLVGHTNSIECIGISSRYNWVATGSIDRTLIIWD-LARQAIRSTCEHDEGVTCLAWLGSS 444 +L GH I + S+ + + S D LIIWD + + V A+ S Sbjct: 66 TLKGHLAKIYAMHWSTDRRHLVSASQDGKLIIWDAYTTNKVHAIPLRSSWVMTCAYAPSG 125 Query: 443 RYVASGCIDGMVRIWDSLSG-----DLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSAR 279 YVA G +D + I++ +AR SGH + D SI++ S D + Sbjct: 126 NYVACGGLDNICSIYNLNQNRDGPTRVARELSGHAGYLSCCRFIND-RSILTSSGDMTCM 184 Query: 278 VFDI 267 +DI Sbjct: 185 KWDI 188
>YA4E_SCHPO (Q09731) Hypothetical WD-repeat protein C31A2.14 in chromosome I| Length = 962 Score = 51.6 bits (122), Expect = 2e-06 Identities = 34/142 (23%), Positives = 74/142 (52%), Gaps = 12/142 (8%) Frame = -2 Query: 656 HIVSINSGQVVGSLVGHTNSIECIGIS--SRYNWVATGSIDRTLIIWD--LARQAIRSTC 489 H+++ + +G HT+ ++ + I S+ VA+G +D+ +I+WD + ++ +R Sbjct: 109 HVLNASCLSTIGE---HTDYVKRVSIPKYSKSPLVASGGLDKRIIVWDYNVGQEVMRFEQ 165 Query: 488 EHD--------EGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLA 333 D GV LA ++ +A+G + +++WD +S GH D V+ + Sbjct: 166 LPDCSLVVGPRSGVYSLA--ANNNIIANGGLQKDIQLWDCVSKKRITDLVGHTDNVRDIL 223 Query: 332 VSADGNSIVSVSTDKSARVFDI 267 +S DG +I++ S+D + +++ + Sbjct: 224 ISDDGRTILTASSDATIKLWSL 245 Score = 33.5 bits (75), Expect = 0.58 Identities = 19/56 (33%), Positives = 30/56 (53%), Gaps = 1/56 (1%) Frame = -2 Query: 626 VGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDL-ARQAIRSTCEHDEGVTCL 462 + LVGHT+++ I IS + T S D T+ +W L A++ + S H + V L Sbjct: 209 ITDLVGHTDNVRDILISDDGRTILTASSDATIKLWSLRAQKCLFSFIAHSDSVWAL 264 Score = 32.3 bits (72), Expect = 1.3 Identities = 16/83 (19%), Positives = 38/83 (45%), Gaps = 1/83 (1%) Frame = -2 Query: 581 ISSRYNWVATGSIDRTLIIWD-LARQAIRSTCEHDEGVTCLAWLGSSRYVASGCIDGMVR 405 +++ N +A G + + + +WD ++++ I H + V + R + + D ++ Sbjct: 182 LAANNNIIANGGLQKDIQLWDCVSKKRITDLVGHTDNVRDILISDDGRTILTASSDATIK 241 Query: 404 IWDSLSGDLARTFSGHRDVVQSL 336 +W + +F H D V +L Sbjct: 242 LWSLRAQKCLFSFIAHSDSVWAL 264
>YJL2_YEAST (P47025) Hypothetical 80.0 kDa Trp-Asp repeats-containing protein| in ASF1-CCT7 intergenic region Length = 714 Score = 51.2 bits (121), Expect = 3e-06 Identities = 37/143 (25%), Positives = 62/143 (43%), Gaps = 23/143 (16%) Frame = -2 Query: 626 VGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCE------------- 486 V + HT+ + + + + + +GS DRT+ WDL T + Sbjct: 495 VHTFEAHTDEVTALSLDPSF--LVSGSQDRTIRQWDLRSGKCLQTIDLSFANVLTTSTNV 552 Query: 485 ----------HDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSL 336 +E + A +A+G DG+VR+WD SG + RT GH D + SL Sbjct: 553 DLSKSTLLTQRNERPSIGALQSFDAALATGTKDGVVRLWDLRSGKVIRTLKGHTDAITSL 612 Query: 335 AVSADGNSIVSVSTDKSARVFDI 267 D +V+ S D++ R++D+ Sbjct: 613 --KFDSACLVTGSYDRTVRIWDL 633 Score = 44.3 bits (103), Expect = 3e-04 Identities = 36/134 (26%), Positives = 61/134 (45%), Gaps = 2/134 (1%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIW--DLARQAIRSTC 489 +V I ++ +G L GH +I C+ I+ Y + TG D L +W +LA+Q + T Sbjct: 422 TVKIWDLSKQNKIGELAGHLATINCMQINRDYGTLVTGGRDAALKLWNLNLAQQLYQET- 480 Query: 488 EHDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSI 309 + +T + ++ S C+ TF H D V A+S D + + Sbjct: 481 ---QNLT-----SPTNHIDSPCV---------------HTFEAHTDEV--TALSLDPSFL 515 Query: 308 VSVSTDKSARVFDI 267 VS S D++ R +D+ Sbjct: 516 VSGSQDRTIRQWDL 529 Score = 42.7 bits (99), Expect = 0.001 Identities = 31/98 (31%), Positives = 53/98 (54%), Gaps = 1/98 (1%) Frame = -2 Query: 560 VATGSIDRTLIIWDL-ARQAIRSTCEHDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSG 384 +ATG+ D + +WDL + + IR+ H + +T L + S + +G D VRIWD +G Sbjct: 579 LATGTKDGVVRLWDLRSGKVIRTLKGHTDAITSLKF--DSACLVTGSYDRTVRIWDLRTG 636 Query: 383 DLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFD 270 L F + V SL + + N+ V V+ + S +++D Sbjct: 637 -LLNKFHAYSAPVLSLDLFQE-NAAVVVADEPSVQIYD 672 Score = 38.9 bits (89), Expect = 0.014 Identities = 20/48 (41%), Positives = 30/48 (62%) Frame = -2 Query: 659 VHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDL 516 V + + SG+V+ +L GHT++I + S + TGS DRT+ IWDL Sbjct: 588 VRLWDLRSGKVIRTLKGHTDAITSLKFDSAC--LVTGSYDRTVRIWDL 633 Score = 33.9 bits (76), Expect = 0.45 Identities = 16/76 (21%), Positives = 39/76 (51%), Gaps = 1/76 (1%) Frame = -2 Query: 485 HDEGVTCLAWLGS-SRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSI 309 HD+ +TCL + +G +D V+IWD + +GH + + ++ D ++ Sbjct: 397 HDDFLTCLDFDAPFGTLCTAGYLDHTVKIWDLSKQNKIGELAGHLATINCMQINRDYGTL 456 Query: 308 VSVSTDKSARVFDISM 261 V+ D + +++++++ Sbjct: 457 VTGGRDAALKLWNLNL 472
>YNA6_YEAST (P41318) Hypothetical 34.0 kDa Trp-Asp repeats-containing protein| in SIS1-MRPL2 intergenic region Length = 303 Score = 51.2 bits (121), Expect = 3e-06 Identities = 29/121 (23%), Positives = 57/121 (47%), Gaps = 1/121 (0%) Frame = -2 Query: 626 VGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCEHDEGVTCLAWLGS 447 V S GH ++ + W+ T S D T+ +WD+ +I +H+ V + + Sbjct: 68 VASFEGHRGNVTSVSFQQDNRWMVTSSEDGTIKVWDVRSPSIPRNYKHNAPVNEVVIHPN 127 Query: 446 SRYVASGCIDGMVRIWDSLSGDLARTFSGHRDV-VQSLAVSADGNSIVSVSTDKSARVFD 270 + S DG +RIWD + D +QSL++++DG+ + + +T + V++ Sbjct: 128 QGELISCDRDGNIRIWDLGENQCTHQLTPEDDTSLQSLSMASDGSMLAAANTKGNCYVWE 187 Query: 269 I 267 + Sbjct: 188 M 188 Score = 40.0 bits (92), Expect = 0.006 Identities = 25/86 (29%), Positives = 41/86 (47%), Gaps = 2/86 (2%) Frame = -2 Query: 608 HTNSIECIGISSRYNWVATGSIDRTLIIWDLARQ-AIRSTCE-HDEGVTCLAWLGSSRYV 435 H+ I I +SS +AT S D T +W + + +T + H V A+ S Y+ Sbjct: 206 HSTYITRILLSSDVKHLATCSADHTARVWSIDDDFKLETTLDGHQRWVWDCAFSADSAYL 265 Query: 434 ASGCIDGMVRIWDSLSGDLARTFSGH 357 + D VR+WD + ++ R + GH Sbjct: 266 VTASSDHYVRLWDLSTREIVRQYGGH 291 Score = 38.9 bits (89), Expect = 0.014 Identities = 28/121 (23%), Positives = 55/121 (45%), Gaps = 9/121 (7%) Frame = -2 Query: 599 SIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCE-------HDEGVTCLAWLGSSR 441 S++ + ++S + +A + +W++ S + H +T + + Sbjct: 161 SLQSLSMASDGSMLAAANTKGNCYVWEMPNHTDASHLKPVTKFRAHSTYITRILLSSDVK 220 Query: 440 YVASGCIDGMVRIWDSLSGD--LARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFDI 267 ++A+ D R+W S+ D L T GH+ V A SAD +V+ S+D R++D+ Sbjct: 221 HLATCSADHTARVW-SIDDDFKLETTLDGHQRWVWDCAFSADSAYLVTASSDHYVRLWDL 279 Query: 266 S 264 S Sbjct: 280 S 280 Score = 30.0 bits (66), Expect = 6.5 Identities = 16/55 (29%), Positives = 28/55 (50%), Gaps = 1/55 (1%) Frame = -2 Query: 620 SLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLA-RQAIRSTCEHDEGVTCLA 459 +L GH + S+ ++ T S D + +WDL+ R+ +R H +G C+A Sbjct: 245 TLDGHQRWVWDCAFSADSAYLVTASSDHYVRLWDLSTREIVRQYGGHHKGAVCVA 299
>PLAP_HUMAN (Q9Y263) Phospholipase A-2-activating protein (PLAP) (PLA2P)| Length = 738 Score = 51.2 bits (121), Expect = 3e-06 Identities = 31/116 (26%), Positives = 60/116 (51%) Frame = -2 Query: 620 SLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCEHDEGVTCLAWLGSSR 441 +L GHT ++ + I + TGS D+T+ +W R R+ H++ V LA L + Sbjct: 89 TLQGHTAAVWAVKILPEQGLMLTGSADKTVKLWKAGR-CERTFSGHEDCVRGLAILSETE 147 Query: 440 YVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVF 273 ++ S D +R W ++G+ + GH + + S++V + V+ + D+S R++ Sbjct: 148 FL-SCANDASIRRW-QITGECLEVYYGHTNYIYSISVFPNCRDFVTTAEDRSLRIW 201
>HIRL_SCHPO (P87314) Histone transcription regulator 1 homolog| Length = 932 Score = 51.2 bits (121), Expect = 3e-06 Identities = 31/141 (21%), Positives = 59/141 (41%), Gaps = 19/141 (13%) Frame = -2 Query: 608 HTNSIECIGISSRYNWVATGSIDRTLIIWDLAR-------------------QAIRSTCE 486 HT ++ + S ++A+GS DR +IIW ++ R Sbjct: 73 HTGTVTSVRFSPNGQYLASGSDDRVVIIWHKEEAIPGLGSTFGSGEKHTENWRSYRRLLG 132 Query: 485 HDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIV 306 HD + L W S+ V S +D + +W+ + + + H+ V+ + G Sbjct: 133 HDNDIQDLCWSYDSQLVVSVGLDSSIIVWNGTTFERLKRIEAHQSHVKGITFDPAGKYFA 192 Query: 305 SVSTDKSARVFDISMFK*EKS 243 + S D++ +V+ +S F EK+ Sbjct: 193 TESDDRTIKVWRVSDFSIEKT 213 Score = 43.1 bits (100), Expect = 7e-04 Identities = 44/154 (28%), Positives = 66/154 (42%), Gaps = 35/154 (22%) Frame = -2 Query: 611 GHTNSIECIGISSRYNWVATGSIDRTLIIW----------------DLARQAIRSTCEHD 480 GH SI I I + +ATG +D T+ IW DL +Q + H Sbjct: 16 GHRLSIFSIHIHPDGSRIATGGLDGTIRIWSTEAINRENENENENEDLPKQ-LCCMSTHT 74 Query: 479 EGVTCLAWLGSSRYVASGCIDGMVRIW---DSLSGDLARTFS----------------GH 357 VT + + + +Y+ASG D +V IW +++ G L TF GH Sbjct: 75 GTVTSVRFSPNGQYLASGSDDRVVIIWHKEEAIPG-LGSTFGSGEKHTENWRSYRRLLGH 133 Query: 356 RDVVQSLAVSADGNSIVSVSTDKSARVFDISMFK 255 + +Q L S D +VSV D S V++ + F+ Sbjct: 134 DNDIQDLCWSYDSQLVVSVGLDSSIIVWNGTTFE 167 Score = 32.0 bits (71), Expect = 1.7 Identities = 18/87 (20%), Positives = 41/87 (47%), Gaps = 1/87 (1%) Frame = -2 Query: 617 LVGHTNSIECIGISSRYNWVATGSIDRTLIIWD-LARQAIRSTCEHDEGVTCLAWLGSSR 441 L+GH N I+ + S V + +D ++I+W+ + ++ H V + + + + Sbjct: 130 LLGHDNDIQDLCWSYDSQLVVSVGLDSSIIVWNGTTFERLKRIEAHQSHVKGITFDPAGK 189 Query: 440 YVASGCIDGMVRIWDSLSGDLARTFSG 360 Y A+ D +++W + +T +G Sbjct: 190 YFATESDDRTIKVWRVSDFSIEKTITG 216
>PLAP_RAT (P54319) Phospholipase A-2-activating protein (PLAP)| Length = 647 Score = 50.8 bits (120), Expect = 4e-06 Identities = 31/116 (26%), Positives = 60/116 (51%) Frame = -2 Query: 620 SLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCEHDEGVTCLAWLGSSR 441 +L GHT ++ + I + TGS D+T+ +W R R+ H++ V LA L + Sbjct: 89 TLQGHTAAVWAVKILPEQGLMLTGSADKTIKLWKAGR-CERTFSGHEDCVRGLAILSETE 147 Query: 440 YVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVF 273 ++ S D +R W ++G+ + GH + + S++V + V+ + D+S R++ Sbjct: 148 FL-SCANDASIRRW-QITGECLGVYYGHTNYIYSISVFPNCRDFVTTAEDRSLRIW 201 Score = 32.0 bits (71), Expect = 1.7 Identities = 24/82 (29%), Positives = 37/82 (45%), Gaps = 2/82 (2%) Frame = -2 Query: 638 SGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLAR--QAIRSTCEHDEGVTC 465 +G+ +G GHTN I I + T + DR+L IW Q IR + + C Sbjct: 163 TGECLGVYYGHTNYIYSISVFPNCRDFVTTAEDRSLRIWKHGECAQTIRLPA---QSIWC 219 Query: 464 LAWLGSSRYVASGCIDGMVRIW 399 L + V G DG++R++ Sbjct: 220 CCVLDNGDIVV-GASDGIIRVF 240
>TLE2_BRARE (O13166) Groucho 2 protein| Length = 761 Score = 50.8 bits (120), Expect = 4e-06 Identities = 30/93 (32%), Positives = 42/93 (45%), Gaps = 3/93 (3%) Frame = -2 Query: 536 TLIIWDLARQAIRSTCEHDEGVTC---LAWLGSSRYVASGCIDGMVRIWDSLSGDLARTF 366 TL IWDLA Q R E LA ++ S C DG + +WD + L R F Sbjct: 544 TLTIWDLASQTPRIKAELTSSAPACYALAISPDAKVCFSCCSDGNIAVWDLHNQTLVRQF 603 Query: 365 SGHRDVVQSLAVSADGNSIVSVSTDKSARVFDI 267 GH D + +S DG + + D + R +D+ Sbjct: 604 QGHTDGASCIDISHDGTKLWTGGLDNTVRSWDL 636 Score = 36.2 bits (82), Expect = 0.090 Identities = 31/126 (24%), Positives = 51/126 (40%), Gaps = 2/126 (1%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCEH 483 ++ + +++ +V GHT+ CI IS + TG +D T+ WDL R +H Sbjct: 588 NIAVWDLHNQTLVRQFQGHTDGASCIDISHDGTKLWTGGLDNTVRSWDLREG--RQLQQH 645 Query: 482 D--EGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSI 309 D + L + + ++A G V + D + H V SL + G Sbjct: 646 DFASQIFSLGYCPTGEWLAVGMESSNVEVLHHTKPDKYQLHL-HESCVLSLKFAYCGKWF 704 Query: 308 VSVSTD 291 VS D Sbjct: 705 VSTGKD 710
>HIR1_YEAST (P32479) Histone transcription regulator 1| Length = 788 Score = 50.8 bits (120), Expect = 4e-06 Identities = 32/133 (24%), Positives = 59/133 (44%), Gaps = 17/133 (12%) Frame = -2 Query: 620 SLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDL-----ARQAIRSTCE---------- 486 S+ HT SI C+ S ++A+GS DR L+IW L ++ A S E Sbjct: 22 SMSRHTGSITCVKFSPDGKYLASGSDDRILLIWALDEEQSSQPAFGSEHEREHWTVRKRL 81 Query: 485 --HDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNS 312 HD + + W S + + +D V +W+ + + + F H+ +V+ + Sbjct: 82 VAHDNDIQDICWAPDSSILVTVGLDRSVIVWNGSTFEKLKRFDVHQSLVKGVVFDPANKY 141 Query: 311 IVSVSTDKSARVF 273 + S D++ ++F Sbjct: 142 FATTSDDRTMKIF 154
>TLE1_BRARE (O13168) Groucho 1 protein (Fragment)| Length = 535 Score = 50.8 bits (120), Expect = 4e-06 Identities = 32/101 (31%), Positives = 46/101 (45%), Gaps = 3/101 (2%) Frame = -2 Query: 560 VATGSIDRTLIIWDLARQAIRSTCEHDEGVTC---LAWLGSSRYVASGCIDGMVRIWDSL 390 +A G + TL IWDLA Q R E LA ++ S C DG + +WD Sbjct: 311 IAGGEVS-TLTIWDLASQTPRIKAELTSSAPACYALAISPDAKVCFSCCSDGNIAVWDLH 369 Query: 389 SGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFDI 267 + L R F GH D + +S DG + + D + R +D+ Sbjct: 370 NQTLVRQFQGHTDGASCIDISHDGPKLWTGGLDNTVRSWDL 410 Score = 35.0 bits (79), Expect = 0.20 Identities = 31/126 (24%), Positives = 51/126 (40%), Gaps = 2/126 (1%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCEH 483 ++ + +++ +V GHT+ CI IS + TG +D T+ WDL R +H Sbjct: 362 NIAVWDLHNQTLVRQFQGHTDGASCIDISHDGPKLWTGGLDNTVRSWDLREG--RQLQQH 419 Query: 482 D--EGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSI 309 D + L + + ++A G V + D + H V SL + G Sbjct: 420 DFTSQIFSLGYCPTGEWLAVGMESSNVEVLHHTKPDKYQLHL-HESCVLSLKSAYCGKWF 478 Query: 308 VSVSTD 291 VS D Sbjct: 479 VSTGKD 484
>WDR48_BRARE (Q6PFM9) WD-repeat protein 48| Length = 677 Score = 50.8 bits (120), Expect = 4e-06 Identities = 32/142 (22%), Positives = 68/142 (47%), Gaps = 10/142 (7%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDL----ARQAIRS 495 +V + + + G + +L H + ++ + + VA+ +DR + +WD+ A A + Sbjct: 98 TVKVWNAHKGFCMSTLRTHKDYVKALAYAKDKELVASAGLDRQIFLWDVNTLTALTASNN 157 Query: 494 TCE------HDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLA 333 T + + + LA + + SG + ++R+WD + GH D V+SL Sbjct: 158 TVTTSSLSGNKDSIYSLAMNQTGTVIISGSTEKVLRVWDPRTCAKLMKLKGHTDNVKSLL 217 Query: 332 VSADGNSIVSVSTDKSARVFDI 267 ++ DG +S S+D + R++ + Sbjct: 218 LNRDGTQCLSGSSDGTIRLWSL 239 Score = 42.0 bits (97), Expect = 0.002 Identities = 25/117 (21%), Positives = 51/117 (43%), Gaps = 4/117 (3%) Frame = -2 Query: 602 NSIECIGISSRYNWVATGSIDRTLIIWDLARQA----IRSTCEHDEGVTCLAWLGSSRYV 435 N + + + N + T D + IW + + I S H + V + + + + Sbjct: 31 NGVNALQLDPALNRLFTAGRDSIIRIWSVNQHKQDPYIASMEHHTDWVNDIILCCNGKTL 90 Query: 434 ASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFDIS 264 S D V++W++ G T H+D V++LA + D + S D+ ++D++ Sbjct: 91 ISASSDTTVKVWNAHKGFCMSTLRTHKDYVKALAYAKDKELVASAGLDRQIFLWDVN 147 Score = 39.3 bits (90), Expect = 0.011 Identities = 33/114 (28%), Positives = 53/114 (46%), Gaps = 3/114 (2%) Frame = -2 Query: 617 LVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCE-HDEGVTCLAWLGSSR 441 L GHT++++ + ++ +GS D T+ +W L +Q +T HDEGV L + Sbjct: 206 LKGHTDNVKSLLLNRDGTQCLSGSSDGTIRLWSLGQQRCIATYRVHDEGVWALQVNEAFT 265 Query: 440 YVASGCIDGMVRIWDSLSGDLARTFSGHRDVV--QSLAVSADGNSIVSVSTDKS 285 ++ SG D + D + D+ + V L SAD + VST KS Sbjct: 266 HIYSGGRDRKIYCTDLRNPDMRVLICEEKAPVLRMELDRSADPPQSIWVSTTKS 319
>YQS1_CAEEL (Q09309) Hypothetical WD-repeat protein F21H12.1| Length = 454 Score = 50.8 bits (120), Expect = 4e-06 Identities = 25/57 (43%), Positives = 36/57 (63%) Frame = -2 Query: 437 VASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFDI 267 VA GC DG V I+D ++ ++ARTFS H V L+ S DG +++ S D S +FD+ Sbjct: 40 VAVGCTDGRVLIYDFMTRNIARTFSAHCLPVSCLSWSRDGRKLLTSSADNSIAMFDV 96 Score = 37.4 bits (85), Expect = 0.040 Identities = 26/113 (23%), Positives = 48/113 (42%), Gaps = 1/113 (0%) Frame = -2 Query: 599 SIECIGISSRYNWVATGSIDRTLIIWD-LARQAIRSTCEHDEGVTCLAWLGSSRYVASGC 423 S C + + VA G D ++I+D + R R+ H V+CL+W R + + Sbjct: 27 SANCCKFNRWGSIVAVGCTDGRVLIYDFMTRNIARTFSAHCLPVSCLSWSRDGRKLLTSS 86 Query: 422 IDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFDIS 264 D + ++D L+G L + V ++ + N + + +K V S Sbjct: 87 ADNSIAMFDVLAGTLLHRIRFNSMVTFAMFHPRNDNKAIVLQVNKQPTVEQFS 139
>YQF1_SCHPO (O94394) Hypothetical WD-repeat protein C126.01c in chromosome III| Length = 369 Score = 50.8 bits (120), Expect = 4e-06 Identities = 32/135 (23%), Positives = 65/135 (48%), Gaps = 8/135 (5%) Frame = -2 Query: 647 SINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIR---STCEHDE 477 ++++G+ V +L+GHT+ ++C+ + + +GS D +LI+WD++ Q R H Sbjct: 118 NVSTGECVETLIGHTDYVKCLLLLEEEGLLLSGSTDASLIVWDVSSQPSRLLYKLTGHSR 177 Query: 476 GVTCLAWLGSSRYVASGCIDGMVRIW--DSLSGDLART--FSGHRDVVQSLAVS-ADGNS 312 G+ C+ ++ + + +R W + G F GH+ V L D + Sbjct: 178 GIECITRQPNTDIFWTCGSESSIRCWHITKVGGSQLEEEGFWGHQSNVYCLLFDPQDSEA 237 Query: 311 IVSVSTDKSARVFDI 267 + + S DK+ R + + Sbjct: 238 LWTASADKTVREWSL 252 Score = 48.1 bits (113), Expect = 2e-05 Identities = 36/135 (26%), Positives = 65/135 (48%), Gaps = 5/135 (3%) Frame = -2 Query: 656 HIVSINSGQVVGS-LVGHTNSIECIGIS---SRYNWVATGSIDRTLIIWDLARQAIRST- 492 HI + Q+ GH +++ C+ S W T S D+T+ W L + T Sbjct: 204 HITKVGGSQLEEEGFWGHQSNVYCLLFDPQDSEALW--TASADKTVREWSLYQGIHEETR 261 Query: 491 CEHDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNS 312 EH + T + L +A+ C D +R+WD+ +G++ +SGH + V + + Sbjct: 262 MEHPDVCTDVLTLADGN-IATACRDEEIRVWDTTTGNVKDIYSGHYESVTKILQWK--SY 318 Query: 311 IVSVSTDKSARVFDI 267 ++S S D++ RV+D+ Sbjct: 319 LISSSLDQTIRVWDL 333 Score = 43.9 bits (102), Expect = 4e-04 Identities = 28/89 (31%), Positives = 44/89 (49%), Gaps = 9/89 (10%) Frame = -2 Query: 503 IRSTCE----HDEGVTC-----LAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRD 351 I TC+ H VTC L G R++ +G D ++ W+ +G+ T GH D Sbjct: 74 INKTCKTYKGHSGPVTCCQIESLRKDGKVRHIYTGSWDHTIKKWNVSTGECVETLIGHTD 133 Query: 350 VVQSLAVSADGNSIVSVSTDKSARVFDIS 264 V+ L + + ++S STD S V+D+S Sbjct: 134 YVKCLLLLEEEGLLLSGSTDASLIVWDVS 162 Score = 39.3 bits (90), Expect = 0.011 Identities = 35/133 (26%), Positives = 52/133 (39%), Gaps = 6/133 (4%) Frame = -2 Query: 650 VSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCE----- 486 VS +++ L GH+ IECI + T + ++ W + + E Sbjct: 161 VSSQPSRLLYKLTGHSRGIECITRQPNTDIFWTCGSESSIRCWHITKVGGSQLEEEGFWG 220 Query: 485 HDEGVTCLAW-LGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSI 309 H V CL + S + + D VR W G T H DV + ADGN I Sbjct: 221 HQSNVYCLLFDPQDSEALWTASADKTVREWSLYQGIHEETRMEHPDVCTDVLTLADGN-I 279 Query: 308 VSVSTDKSARVFD 270 + D+ RV+D Sbjct: 280 ATACRDEEIRVWD 292
>GBB_SCHPO (Q10282) Guanine nucleotide-binding protein beta subunit| Length = 305 Score = 50.4 bits (119), Expect = 5e-06 Identities = 35/120 (29%), Positives = 58/120 (48%), Gaps = 3/120 (2%) Frame = -2 Query: 617 LVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLAR-QAIRSTCEHDEGVTCLAWLGS-- 447 LVGH + C + + TGS D+T + WD+ + +AI H+ + L +L S Sbjct: 102 LVGHAGFVSCCKYVDDGH-LLTGSGDKTCMFWDIEQAKAISVLKGHEMDIVSLDFLPSNP 160 Query: 446 SRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFDI 267 + +V GC D + ++WD + TF G+ + S++ V+ + D AR FDI Sbjct: 161 NLFVTGGC-DKLAKLWDLRAAYCCATFPGNTSDINSISFFPSNADFVTGAEDGIARCFDI 219 Score = 39.3 bits (90), Expect = 0.011 Identities = 34/171 (19%), Positives = 63/171 (36%), Gaps = 44/171 (25%) Frame = -2 Query: 644 INSGQVVGSLVGHTNSIECIG-ISSRYNWVATGSIDRTLIIWDLARQAIRSTCE-HDEGV 471 I + + L GH I + + S N TG D+ +WDL +T + + Sbjct: 134 IEQAKAISVLKGHEMDIVSLDFLPSNPNLFVTGGCDKLAKLWDLRAAYCCATFPGNTSDI 193 Query: 470 TCLAWLGSSRYVASGCIDGMVR-------------------------------------- 405 +++ S+ +G DG+ R Sbjct: 194 NSISFFPSNADFVTGAEDGIARCFDIRASAEIFQYSSPSSSPINSVLFSKSGKLLFIAKD 253 Query: 404 ----IWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFDIS 264 +WDS+S + +GH + + SLA+++DG + + S D+ R++ S Sbjct: 254 KTCEVWDSISSKTITSLTGHENRISSLALTSDGTMLATGSWDECVRLWSSS 304
>YRIQ_CAEEL (P90794) Hypothetical WD-repeat protein D2030.9| Length = 571 Score = 50.4 bits (119), Expect = 5e-06 Identities = 47/179 (26%), Positives = 79/179 (44%), Gaps = 17/179 (9%) Frame = -2 Query: 599 SIECIGISSRYNWVATGSIDRTLIIWDLA-RQAIRSTC---EHDEGVTCLAWLGSSRYVA 432 ++ C+ S + G+ ++ ++D+ R+ IR+ E D C A LGS+ + Sbjct: 270 AVFCVKFSDSSEQIVCGTSQYSIHVFDVEQRRRIRTIVNAHEDDVNSVCFADLGSNLIYS 329 Query: 431 SGCIDGMVRIWDSLS---GDL--ARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFDI 267 +G DG+V++WD + GD+ F+GHRD V + D ++S S D++ +V+D+ Sbjct: 330 AGD-DGLVKVWDKRAWSDGDVEPVGVFAGHRDGVTHVDSRQDERYLLSNSKDQTIKVWDL 388 Query: 266 SMFK-------*EKS*QQQHG*FGWSF-WPVKSGGLLSLYGQELYLQACSHHGALKTLV 114 F Q QH W + W GL + + H L TLV Sbjct: 389 RKFSNMSGVEATRACVQSQH----WDYRWQPAPPGLCQPVAGDTSVMTLRGHSVLHTLV 443 Score = 39.3 bits (90), Expect = 0.011 Identities = 37/154 (24%), Positives = 60/154 (38%), Gaps = 42/154 (27%) Frame = -2 Query: 626 VGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLAR-------QAIRST-------- 492 VG GH + + + ++ + S D+T+ +WDL + +A R+ Sbjct: 352 VGVFAGHRDGVTHVDSRQDERYLLSNSKDQTIKVWDLRKFSNMSGVEATRACVQSQHWDY 411 Query: 491 ---------CEHDEGVTCLAWL-GSS-----------------RYVASGCIDGMVRIWDS 393 C+ G T + L G S RY+ +GC G V ++D Sbjct: 412 RWQPAPPGLCQPVAGDTSVMTLRGHSVLHTLVRANFSPESTGRRYIYTGCARGEVVVYDI 471 Query: 392 LSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTD 291 +SG ++R GH VV+ N IVS + D Sbjct: 472 MSGTVSRRLKGHTAVVRECDWHPTENEIVSSAWD 505
>FAN_HUMAN (Q92636) Protein FAN (Factor associated with N-SMase activation)| (Factor associated with neutral sphingomyelinase activation) Length = 917 Score = 50.4 bits (119), Expect = 5e-06 Identities = 37/142 (26%), Positives = 60/142 (42%), Gaps = 10/142 (7%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRST--- 492 +V+ SI G+ +L+GH +++ I N + + S D T+ +W + T Sbjct: 695 NVYFYSIAFGRRQDTLMGHDDAVS--KICWHDNRLYSASWDSTVKVWSGVPAEMPGTKRH 752 Query: 491 -------CEHDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLA 333 EHD V ++ +S + SG +G V IWD + L H +V A Sbjct: 753 HFDLLAELEHDVSVDTISLNAASTLLVSGTKEGTVNIWDLTTATLMHQIPCHSGIVCDTA 812 Query: 332 VSADGNSIVSVSTDKSARVFDI 267 S D ++S TD V D+ Sbjct: 813 FSPDSRHVLSTGTDGCLNVIDV 834 Score = 43.9 bits (102), Expect = 4e-04 Identities = 29/125 (23%), Positives = 55/125 (44%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCEH 483 +V+I + + ++ + H+ + S V + D L + D+ + S+ Sbjct: 786 TVNIWDLTTATLMHQIPCHSGIVCDTAFSPDSRHVLSTGTDGCLNVIDVQTGMLISSMTS 845 Query: 482 DEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVS 303 DE TC W G+S V SG G + +WD L ++ GH V + ++ +SI++ Sbjct: 846 DEPQTCFVWDGNS--VLSGSQSGELLVWDLLGAKISERIQGHTGAVTCIWMNEQCSSIIT 903 Query: 302 VSTDK 288 D+ Sbjct: 904 GGEDR 908 Score = 32.3 bits (72), Expect = 1.3 Identities = 12/32 (37%), Positives = 20/32 (62%) Frame = -2 Query: 611 GHTNSIECIGISSRYNWVATGSIDRTLIIWDL 516 GHT ++ CI ++ + + + TG DR +I W L Sbjct: 884 GHTGAVTCIWMNEQCSSIITGGEDRQIIFWKL 915
>SWD3_YEAST (P38123) COMPASS component SWD3 (Complex proteins associated with| SET1 protein SWD3) (Set1C component SWD3) Length = 315 Score = 50.4 bits (119), Expect = 5e-06 Identities = 29/106 (27%), Positives = 58/106 (54%), Gaps = 2/106 (1%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCE- 486 SV I+ ++ G ++ + +GHT + + + + N + T S+D ++ IWD ++ T Sbjct: 78 SVEIIHLSYG-LLHTFIGHTAPVISLTFNRKGNLLFTSSMDESIKIWDTLNGSLMKTISA 136 Query: 485 HDEGVTCL-AWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRD 351 H E V + + S ++SG DG++RI+D+ +G +T + +D Sbjct: 137 HSEAVVSVDVPMNDSSILSSGSYDGLIRIFDAETGHCLKTLTYDKD 182 Score = 48.5 bits (114), Expect = 2e-05 Identities = 38/133 (28%), Positives = 63/133 (47%), Gaps = 2/133 (1%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLV-GHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCE 486 ++ I IN V +LV H + S +AT S D ++ I L+ + + Sbjct: 35 NILIYDINRRTVSQTLVTSHARPFSELCWSPDGQCIATASDDFSVEIIHLSYGLLHTFIG 94 Query: 485 HDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIV 306 H V L + + + +D ++IWD+L+G L +T S H + V S+ V + +SI+ Sbjct: 95 HTAPVISLTFNRKGNLLFTSSMDESIKIWDTLNGSLMKTISAHSEAVVSVDVPMNDSSIL 154 Query: 305 SV-STDKSARVFD 270 S S D R+FD Sbjct: 155 SSGSYDGLIRIFD 167 Score = 37.4 bits (85), Expect = 0.040 Identities = 23/109 (21%), Positives = 54/109 (49%), Gaps = 10/109 (9%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWV-ATGSIDRTLIIWDLARQAIRSTCE 486 S+ I +G ++ ++ H+ ++ + + + + ++GS D + I+D T Sbjct: 119 SIKIWDTLNGSLMKTISAHSEAVVSVDVPMNDSSILSSGSYDGLIRIFDAETGHCLKTLT 178 Query: 485 HDEG---------VTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTF 366 +D+ ++ + + ++RY+ +DG+V+IWD + G + RTF Sbjct: 179 YDKDWKRENGVVPISQVKFSENARYLLVKSLDGVVKIWDCIGGCVVRTF 227
>FAN_MOUSE (O35242) Protein FAN (Factor associated with N-SMase activation)| (Factor associated with neutral sphingomyelinase activation) Length = 920 Score = 50.1 bits (118), Expect = 6e-06 Identities = 39/142 (27%), Positives = 59/142 (41%), Gaps = 10/142 (7%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRST--- 492 +V+ SI G+ +L+GH +++ I + + +GS D T+ +W + T Sbjct: 698 NVYFYSIAFGRRQDTLMGHDDAVS--KICWHNDRLYSGSWDSTVKVWSGVPAEMPGTKRH 755 Query: 491 -------CEHDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLA 333 EHD V + S + SG +GMV IWD + L S H V A Sbjct: 756 QFDLLAELEHDVSVNTINLNAVSTLLVSGTKEGMVNIWDLTTATLLHQTSCHSGTVCDAA 815 Query: 332 VSADGNSIVSVSTDKSARVFDI 267 S D I+S D V D+ Sbjct: 816 FSPDSRHILSTGVDGCLNVIDV 837 Score = 42.0 bits (97), Expect = 0.002 Identities = 27/124 (21%), Positives = 54/124 (43%) Frame = -2 Query: 659 VHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCEHD 480 V+I + + ++ H+ ++ S + + +D L + D+ + S+ D Sbjct: 790 VNIWDLTTATLLHQTSCHSGTVCDAAFSPDSRHILSTGVDGCLNVIDVQTGMLISSMASD 849 Query: 479 EGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSV 300 E C W G+S V SG G + +WD L ++ GH V + ++ +SI++ Sbjct: 850 EPQRCFVWDGNS--VLSGSRSGELLVWDLLGAKVSERIQGHTGAVTCMWMNEQCSSIITG 907 Query: 299 STDK 288 D+ Sbjct: 908 GEDR 911 Score = 30.0 bits (66), Expect = 6.5 Identities = 10/32 (31%), Positives = 20/32 (62%) Frame = -2 Query: 611 GHTNSIECIGISSRYNWVATGSIDRTLIIWDL 516 GHT ++ C+ ++ + + + TG DR ++ W L Sbjct: 887 GHTGAVTCMWMNEQCSSIITGGEDRQIMFWKL 918
>RAE1L_ARATH (Q38942) Rae1-like protein At1g80670| Length = 349 Score = 50.1 bits (118), Expect = 6e-06 Identities = 31/117 (26%), Positives = 54/117 (46%), Gaps = 6/117 (5%) Frame = -2 Query: 602 NSIECIGISSRYNWVATGSIDRTLIIWDLARQ------AIRSTCEHDEGVTCLAWLGSSR 441 +SI + S R + + S D + W+++R A +++ HD+ V C AW Sbjct: 26 DSISSLSFSPRADILVATSWDNQVRCWEISRSGASLASAPKASISHDQPVLCSAWKDDGT 85 Query: 440 YVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFD 270 V SG D ++W LSG T + H + ++A N + + S DK+ + +D Sbjct: 86 TVFSGGCDKQAKMWPLLSGGQPVTVAMHEGPIAAMAWIPGMNLLATGSWDKTLKYWD 142 Score = 31.2 bits (69), Expect = 2.9 Identities = 17/75 (22%), Positives = 30/75 (40%), Gaps = 1/75 (1%) Frame = -2 Query: 614 VGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCEHDEG-VTCLAWLGSSRY 438 + H + C V +G D+ +W L T EG + +AW+ Sbjct: 69 ISHDQPVLCSAWKDDGTTVFSGGCDKQAKMWPLLSGGQPVTVAMHEGPIAAMAWIPGMNL 128 Query: 437 VASGCIDGMVRIWDS 393 +A+G D ++ WD+ Sbjct: 129 LATGSWDKTLKYWDT 143
>NEDD1_HUMAN (Q8NHV4) Protein NEDD1| Length = 660 Score = 50.1 bits (118), Expect = 6e-06 Identities = 33/113 (29%), Positives = 64/113 (56%), Gaps = 4/113 (3%) Frame = -2 Query: 590 CIGISSRYNWVATGSIDRTLIIWDLARQAI-RSTCEHDEGVTCLAWLGSSRYVASGCIDG 414 C+ ++S ++ +G ++ T+ IWDL + + RS +H + VTC+ + + Y+ASG + G Sbjct: 82 CVNLNSTSMYLVSGGLNNTVNIWDLKSKRVHRSLKDHKDQVTCVTYNWNDCYIASGSLSG 141 Query: 413 MVRIWDSLSGDLARTFSGH--RDVVQSLAVSADGNSIV-SVSTDKSARVFDIS 264 + I S++ +L+ T GH V+ L S S++ SVS + ++D++ Sbjct: 142 EI-ILHSVTTNLSSTPFGHGSNQSVRHLKYSLFKKSLLGSVSDNGIVTLWDVN 193 Score = 35.0 bits (79), Expect = 0.20 Identities = 31/109 (28%), Positives = 47/109 (43%), Gaps = 4/109 (3%) Frame = -2 Query: 659 VHIVSINSGQVVGSLVGHTN--SIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCE 486 + I +S +V HT+ I I SS N++ T S I+ + E Sbjct: 14 IKIWDASSMTLVDKFNPHTSPHGISSICWSSNNNFLVTASSSGDKIVVSSCKCKPVPLLE 73 Query: 485 HDEGV--TCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVV 345 EG TC+ +S Y+ SG ++ V IWD S + R+ H+D V Sbjct: 74 LAEGQKQTCVNLNSTSMYLVSGGLNNTVNIWDLKSKRVHRSLKDHKDQV 122
>WDR18_MOUSE (Q4VBE8) WD-repeat protein 18| Length = 431 Score = 49.7 bits (117), Expect = 8e-06 Identities = 31/110 (28%), Positives = 56/110 (50%), Gaps = 12/110 (10%) Frame = -2 Query: 560 VATGSIDRTLIIWDLARQAIRSTCEHDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSG- 384 VAT S+D+T+ +W ++ + + D G+T + + ++ G DG + D S Sbjct: 189 VATASLDQTVKLWAISSGDLLLSVLFDMGITSVTMDLAEHHIFCGGSDGSIFQVDLCSWP 248 Query: 383 -----------DLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFDI 267 + + F GHR+ V L+VS DG+ ++S S D+S R++D+ Sbjct: 249 GLREHSFQPEQNTGKVFKGHRNQVTCLSVSTDGSVLLSGSHDESVRLWDV 298 Score = 34.3 bits (77), Expect = 0.34 Identities = 19/61 (31%), Positives = 29/61 (47%) Frame = -2 Query: 473 VTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVST 294 VTCL + YV +G + + +W+ +G+L S H V L + DG+ VS Sbjct: 83 VTCLTTAPNGLYVLAGIAES-IYLWEVCTGNLLVILSRHYQDVSCLKFTGDGSHFVSAGK 141 Query: 293 D 291 D Sbjct: 142 D 142 Score = 32.3 bits (72), Expect = 1.3 Identities = 15/50 (30%), Positives = 32/50 (64%), Gaps = 1/50 (2%) Frame = -2 Query: 641 NSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDL-ARQAIRS 495 N+G+V GH N + C+ +S+ + + +GS D ++ +WD+ ++Q +R+ Sbjct: 260 NTGKV---FKGHRNQVTCLSVSTDGSVLLSGSHDESVRLWDVKSKQCLRT 306
>POP3_SCHPO (O74184) WD-repeat protein pop3 (WD-repeat protein wat1)| Length = 314 Score = 49.7 bits (117), Expect = 8e-06 Identities = 29/117 (24%), Positives = 53/117 (45%), Gaps = 1/117 (0%) Frame = -2 Query: 650 VSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCEHDEGV 471 ++ +S + + GHTN++ I W+AT S D T+ +WD+ +++ +H V Sbjct: 68 INTSSQMPLMTFEGHTNNVTAIAFHCDGKWLATSSEDGTVKVWDMRAPSVQRNYDHKSPV 127 Query: 470 TCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDV-VQSLAVSADGNSIVS 303 L + + S G VR WD DV + S+ V +DG+ +++ Sbjct: 128 NDLLIHPNQGELLSCDQSGRVRAWDLGENSCTHELIPEEDVPMSSITVGSDGSMLIA 184 Score = 42.0 bits (97), Expect = 0.002 Identities = 29/105 (27%), Positives = 45/105 (42%), Gaps = 3/105 (2%) Frame = -2 Query: 632 QVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIW---DLARQAIRSTCEHDEGVTCL 462 Q V H I +S +AT S D T+ IW D++ R H V Sbjct: 206 QPVVKFQAHQRYITRCVLSPDVKHLATCSADATVNIWSTEDMSFMLERRLQGHQRWVWDC 265 Query: 461 AWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVS 327 A+ S Y+ + D + R+W+ SG+ R +SGH +A++ Sbjct: 266 AFSADSTYLVTASSDHVARLWELSSGETIRQYSGHHKAAVCVALN 310 Score = 37.7 bits (86), Expect = 0.031 Identities = 23/76 (30%), Positives = 38/76 (50%), Gaps = 2/76 (2%) Frame = -2 Query: 485 HDEGVTCLAWLGSSRYVASGCIDGMVRIW--DSLSGDLARTFSGHRDVVQSLAVSADGNS 312 H +T +++A+ D V IW + +S L R GH+ V A SAD Sbjct: 214 HQRYITRCVLSPDVKHLATCSADATVNIWSTEDMSFMLERRLQGHQRWVWDCAFSADSTY 273 Query: 311 IVSVSTDKSARVFDIS 264 +V+ S+D AR++++S Sbjct: 274 LVTASSDHVARLWELS 289 Score = 32.7 bits (73), Expect = 1.00 Identities = 21/100 (21%), Positives = 43/100 (43%), Gaps = 2/100 (2%) Frame = -2 Query: 560 VATGSIDRTLIIWDLARQAIRSTCEHDEGVTCLAWLGSSRYVASGCIDGMVRIWD--SLS 387 + + D T+ W+ T +H + + + + + VR++D + S Sbjct: 13 LVSSGYDHTIRFWEALSGICSRTIQHADSQVNRLCISPDKKFLAAAGNPHVRLYDINTSS 72 Query: 386 GDLARTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFDI 267 TF GH + V ++A DG + + S D + +V+D+ Sbjct: 73 QMPLMTFEGHTNNVTAIAFHCDGKWLATSSEDGTVKVWDM 112
>WSB2_MOUSE (O54929) WD repeat and SOCS box-containing protein 2 (WSB-2) (SOCS| box-containing WD protein SWiP-2) Length = 404 Score = 49.7 bits (117), Expect = 8e-06 Identities = 24/59 (40%), Positives = 40/59 (67%), Gaps = 1/59 (1%) Frame = -2 Query: 437 VASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSI-VSVSTDKSARVFDIS 264 +A+G DG ++IW+ +G L SGH+DVV+ L+ + G+ I VS S DK+ R++D++ Sbjct: 126 LATGLNDGQIKIWEVQTGLLLLNLSGHQDVVRDLSFTPSGSLILVSASRDKTLRIWDLN 184 Score = 45.1 bits (105), Expect = 2e-04 Identities = 34/133 (25%), Positives = 60/133 (45%), Gaps = 3/133 (2%) Frame = -2 Query: 659 VHIVSINSGQVVGSLVGHTNSIECIGISSRYNWV-ATGSIDRTLIIWDLARQA--IRSTC 489 + I + +G ++ +L GH + + + + + + + S D+TL IWDL + I+ Sbjct: 135 IKIWEVQTGLLLLNLSGHQDVVRDLSFTPSGSLILVSASRDKTLRIWDLNKHGKQIQVLS 194 Query: 488 EHDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSI 309 H + V C + + S + V +W S L R GH+ V S S D + Sbjct: 195 GHLQWVYCCSISPDCSMLCSAAGEKSVFLWSMRSYTLIRKLEGHQSSVVSCDFSPDSALL 254 Query: 308 VSVSTDKSARVFD 270 V+ S D S ++D Sbjct: 255 VTASYDTSVIMWD 267 Score = 31.6 bits (70), Expect = 2.2 Identities = 24/101 (23%), Positives = 43/101 (42%), Gaps = 13/101 (12%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWD---------LAR 510 SV + S+ S ++ L GH +S+ S + T S D ++I+WD L Sbjct: 220 SVFLWSMRSYTLIRKLEGHQSSVVSCDFSPDSALLVTASYDTSVIMWDPYTGARLRSLHH 279 Query: 509 QAIRSTCE----HDEGVTCLAWLGSSRYVASGCIDGMVRIW 399 + T + H + + + Y+A+ D ++RIW Sbjct: 280 TQLEPTMDDSDVHMSSLRSVCFSPEGLYLATVADDRLLRIW 320
>WSB2_HUMAN (Q9NYS7) WD repeat and SOCS box-containing protein 2 (WSB-2) (CS| box-containing WD protein) Length = 404 Score = 49.7 bits (117), Expect = 8e-06 Identities = 24/59 (40%), Positives = 40/59 (67%), Gaps = 1/59 (1%) Frame = -2 Query: 437 VASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSI-VSVSTDKSARVFDIS 264 +A+G DG ++IW+ +G L SGH+DVV+ L+ + G+ I VS S DK+ R++D++ Sbjct: 126 LATGLNDGQIKIWEVQTGLLLLNLSGHQDVVRDLSFTPSGSLILVSASRDKTLRIWDLN 184 Score = 43.9 bits (102), Expect = 4e-04 Identities = 33/133 (24%), Positives = 60/133 (45%), Gaps = 3/133 (2%) Frame = -2 Query: 659 VHIVSINSGQVVGSLVGHTNSIECIGISSRYNWV-ATGSIDRTLIIWDLARQA--IRSTC 489 + I + +G ++ +L GH + + + + + + + S D+TL IWDL + I+ Sbjct: 135 IKIWEVQTGLLLLNLSGHQDVVRDLSFTPSGSLILVSASRDKTLRIWDLNKHGKQIQVLS 194 Query: 488 EHDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSI 309 H + V C + + S + V +W S L R GH+ V S S D + Sbjct: 195 GHLQWVYCCSISPDCSMLCSAAGEKSVFLWSMRSYTLIRKLEGHQSSVVSCDFSPDSALL 254 Query: 308 VSVSTDKSARVFD 270 V+ S D + ++D Sbjct: 255 VTASYDTNVIMWD 267 Score = 30.4 bits (67), Expect = 4.9 Identities = 23/101 (22%), Positives = 41/101 (40%), Gaps = 13/101 (12%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWD------------ 519 SV + S+ S ++ L GH +S+ S + T S D +I+WD Sbjct: 220 SVFLWSMRSYTLIRKLEGHQSSVVSCDFSPDSALLVTASYDTNVIMWDPYTGERLRSLHH 279 Query: 518 -LARQAIRSTCEHDEGVTCLAWLGSSRYVASGCIDGMVRIW 399 A+ + H + + + Y+A+ D ++RIW Sbjct: 280 TQVDPAMDDSDVHISSLRSVCFSPEGLYLATVADDRLLRIW 320
>WDR22_MOUSE (Q80T85) WD-repeat protein 22| Length = 946 Score = 49.3 bits (116), Expect = 1e-05 Identities = 39/126 (30%), Positives = 58/126 (46%), Gaps = 9/126 (7%) Frame = -2 Query: 617 LVGHTNSIECIGISSRYN-WVATGSIDRTLIIWDLARQAIRSTC-------EHDEGVTCL 462 L+GH + I S+ W+ +G DR +++W + QAI S EH + CL Sbjct: 49 LLGHFGCVNAIEFSNNGGQWLVSGGDDRRVLLWHM-EQAIHSRVKPIQLKGEHHSNIFCL 107 Query: 461 AWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVS-ADGNSIVSVSTDKS 285 A+ + V SG D V + D S + F+ H D V L+VS + N S S D Sbjct: 108 AFNSGNTKVFSGGNDEQVILHDVESSETLDVFA-HEDAVYGLSVSPVNDNIFASSSDDGR 166 Query: 284 ARVFDI 267 ++DI Sbjct: 167 VLIWDI 172
>Y1491_SYNY3 (P74598) Hypothetical WD-repeat protein sll1491| Length = 348 Score = 49.3 bits (116), Expect = 1e-05 Identities = 29/97 (29%), Positives = 54/97 (55%), Gaps = 1/97 (1%) Frame = -2 Query: 551 GSIDRTLIIWDLA-RQAIRSTCEHDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLA 375 G++ + W+LA + + S + +A ++R+VA+ +G + I+D +G Sbjct: 248 GAVRNFVKAWNLADAKELFSVRGPSLEINTIAVSPNNRWVATANKEGTIMIFDLANGKQV 307 Query: 374 RTFSGHRDVVQSLAVSADGNSIVSVSTDKSARVFDIS 264 T GH+ V SLA S DGN++ S + DK+ +++D+S Sbjct: 308 TTLRGHQGWVLSLAFSPDGNTLYSGAEDKTVKIWDLS 344 Score = 43.5 bits (101), Expect = 6e-04 Identities = 32/123 (26%), Positives = 55/123 (44%), Gaps = 4/123 (3%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGIS-SRYNWVATGSIDRTLIIWDLARQAIRSTCE 486 +V + + G V +LVGHT+ + + S V+ DRT+ IW+ A + T Sbjct: 125 NVDVRRVRDGMRVETLVGHTDKVSGVAFSPDGETIVSVSGGDRTIRIWERASGNLIQTLA 184 Query: 485 HDEG-VTCLAWLGSSRYVASGCI--DGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGN 315 + G T + + +G I D ++ WD+ + +L T + LAV+ DG Sbjct: 185 DNLGPTTSVVFTPDGSQFITGAIGQDRTIKFWDANTFELLGTSPQQPGFINGLAVTPDGR 244 Query: 314 SIV 306 +V Sbjct: 245 KLV 247 Score = 40.8 bits (94), Expect = 0.004 Identities = 25/76 (32%), Positives = 39/76 (51%), Gaps = 1/76 (1%) Frame = -2 Query: 620 SLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLAR-QAIRSTCEHDEGVTCLAWLGSS 444 S+ G + I I +S WVAT + + T++I+DLA + + + H V LA+ Sbjct: 267 SVRGPSLEINTIAVSPNNRWVATANKEGTIMIFDLANGKQVTTLRGHQGWVLSLAFSPDG 326 Query: 443 RYVASGCIDGMVRIWD 396 + SG D V+IWD Sbjct: 327 NTLYSGAEDKTVKIWD 342 Score = 38.9 bits (89), Expect = 0.014 Identities = 34/121 (28%), Positives = 54/121 (44%), Gaps = 2/121 (1%) Frame = -2 Query: 626 VGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQ-AIRSTCEHDEGVTCLAWLG 450 V +L G I + I+ ++A + D + + DLA Q + S LA Sbjct: 54 VENLSGFQGIITALNITPDGKYLAVATADNQITLIDLANQEVVYSQRSPVNNFADLAISA 113 Query: 449 SSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIVSVS-TDKSARVF 273 +++A D V + G T GH D V +A S DG +IVSVS D++ R++ Sbjct: 114 DGQWLAIAA-DNNVDVRRVRDGMRVETLVGHTDKVSGVAFSPDGETIVSVSGGDRTIRIW 172 Query: 272 D 270 + Sbjct: 173 E 173 Score = 37.7 bits (86), Expect = 0.031 Identities = 29/148 (19%), Positives = 68/148 (45%), Gaps = 3/148 (2%) Frame = -2 Query: 659 VHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCEHD 480 + ++ + + +VV S N+ + IS+ W+A + + + + + H Sbjct: 85 ITLIDLANQEVVYSQRSPVNNFADLAISADGQWLAIAADNNVDVRRVRDGMRVETLVGHT 144 Query: 479 EGVTCLAWLGSSRYVAS-GCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSIV- 306 + V+ +A+ + S D +RIW+ SG+L +T + + S+ + DG+ + Sbjct: 145 DKVSGVAFSPDGETIVSVSGGDRTIRIWERASGNLIQTLADNLGPTTSVVFTPDGSQFIT 204 Query: 305 -SVSTDKSARVFDISMFK*EKS*QQQHG 225 ++ D++ + +D + F+ + QQ G Sbjct: 205 GAIGQDRTIKFWDANTFELLGTSPQQPG 232 Score = 31.6 bits (70), Expect = 2.2 Identities = 16/53 (30%), Positives = 30/53 (56%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQA 504 ++ I + +G+ V +L GH + + S N + +G+ D+T+ IWDL+ A Sbjct: 295 TIMIFDLANGKQVTTLRGHQGWVLSLAFSPDGNTLYSGAEDKTVKIWDLSALA 347
>TLE4_MOUSE (Q62441) Transducin-like enhancer protein 4 (Groucho-related| protein 4) (Grg-4) Length = 766 Score = 49.3 bits (116), Expect = 1e-05 Identities = 30/93 (32%), Positives = 41/93 (44%), Gaps = 3/93 (3%) Frame = -2 Query: 536 TLIIWDLARQAIRSTCEHDEGVTC---LAWLGSSRYVASGCIDGMVRIWDSLSGDLARTF 366 TL IWDLA R E LA S+ S C DG + +WD + L R F Sbjct: 549 TLSIWDLAAPTPRIKAELTSSAPACYALAISPDSKVCFSCCSDGNIAVWDLHNQTLVRQF 608 Query: 365 SGHRDVVQSLAVSADGNSIVSVSTDKSARVFDI 267 GH D + +S DG + + D + R +D+ Sbjct: 609 QGHTDGASCIDISNDGTKLWTGGLDNTVRSWDL 641 Score = 37.0 bits (84), Expect = 0.053 Identities = 31/126 (24%), Positives = 53/126 (42%), Gaps = 2/126 (1%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCEH 483 ++ + +++ +V GHT+ CI IS+ + TG +D T+ WDL R +H Sbjct: 593 NIAVWDLHNQTLVRQFQGHTDGASCIDISNDGTKLWTGGLDNTVRSWDLREG--RQLQQH 650 Query: 482 D--EGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSI 309 D + L + + ++A G + V + D + H V SL + G Sbjct: 651 DFTSQIFSLGYCPTGEWLAVGMENSNVEVLHVTKPDKYQLHL-HESCVLSLKFAHCGKWF 709 Query: 308 VSVSTD 291 VS D Sbjct: 710 VSTGKD 715
>TLE4_HUMAN (Q04727) Transducin-like enhancer protein 4| Length = 766 Score = 49.3 bits (116), Expect = 1e-05 Identities = 30/93 (32%), Positives = 41/93 (44%), Gaps = 3/93 (3%) Frame = -2 Query: 536 TLIIWDLARQAIRSTCEHDEGVTC---LAWLGSSRYVASGCIDGMVRIWDSLSGDLARTF 366 TL IWDLA R E LA S+ S C DG + +WD + L R F Sbjct: 549 TLSIWDLAAPTPRIKAELTSSAPACYALAISPDSKVCFSCCSDGNIAVWDLHNQTLVRQF 608 Query: 365 SGHRDVVQSLAVSADGNSIVSVSTDKSARVFDI 267 GH D + +S DG + + D + R +D+ Sbjct: 609 QGHTDGASCIDISNDGTKLWTGGLDNTVRSWDL 641 Score = 37.0 bits (84), Expect = 0.053 Identities = 31/126 (24%), Positives = 53/126 (42%), Gaps = 2/126 (1%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCEH 483 ++ + +++ +V GHT+ CI IS+ + TG +D T+ WDL R +H Sbjct: 593 NIAVWDLHNQTLVRQFQGHTDGASCIDISNDGTKLWTGGLDNTVRSWDLREG--RQLQQH 650 Query: 482 D--EGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSI 309 D + L + + ++A G + V + D + H V SL + G Sbjct: 651 DFTSQIFSLGYCPTGEWLAVGMENSNVEVLHVTKPDKYQLHL-HESCVLSLKFAHCGKWF 709 Query: 308 VSVSTD 291 VS D Sbjct: 710 VSTGKD 715
>WDR22_HUMAN (Q96JK2) WD-repeat protein 22 (Breakpoint cluster region protein 2)| (BCRP2) Length = 942 Score = 49.3 bits (116), Expect = 1e-05 Identities = 39/126 (30%), Positives = 58/126 (46%), Gaps = 9/126 (7%) Frame = -2 Query: 617 LVGHTNSIECIGISSRYN-WVATGSIDRTLIIWDLARQAIRSTC-------EHDEGVTCL 462 L+GH + I S+ W+ +G DR +++W + QAI S EH + CL Sbjct: 49 LLGHFGCVNAIEFSNNGGQWLVSGGDDRRVLLWHM-EQAIHSRVKPIQLKGEHHSNIFCL 107 Query: 461 AWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVS-ADGNSIVSVSTDKS 285 A+ + V SG D V + D S + F+ H D V L+VS + N S S D Sbjct: 108 AFNSGNTKVFSGGNDEQVILHDVESSETLDVFA-HEDAVYGLSVSPVNDNIFASSSDDGR 166 Query: 284 ARVFDI 267 ++DI Sbjct: 167 VLIWDI 172
>TLE1_MOUSE (Q62440) Transducin-like enhancer protein 1 (Groucho-related| protein 1) (Grg-1) Length = 770 Score = 49.3 bits (116), Expect = 1e-05 Identities = 30/93 (32%), Positives = 41/93 (44%), Gaps = 3/93 (3%) Frame = -2 Query: 536 TLIIWDLARQAIRSTCEHDEGVTC---LAWLGSSRYVASGCIDGMVRIWDSLSGDLARTF 366 TL IWDLA R E LA S+ S C DG + +WD + L R F Sbjct: 553 TLSIWDLAAPTPRIKAELTSSAPACYALAISPDSKVCFSCCSDGNIAVWDLHNQTLVRQF 612 Query: 365 SGHRDVVQSLAVSADGNSIVSVSTDKSARVFDI 267 GH D + +S DG + + D + R +D+ Sbjct: 613 QGHTDGASCIDISNDGTKLWTGGLDNTVRSWDL 645 Score = 35.8 bits (81), Expect = 0.12 Identities = 31/126 (24%), Positives = 52/126 (41%), Gaps = 2/126 (1%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCEH 483 ++ + +++ +V GHT+ CI IS+ + TG +D T+ WDL R +H Sbjct: 597 NIAVWDLHNQTLVRQFQGHTDGASCIDISNDGTKLWTGGLDNTVRSWDLREG--RQLQQH 654 Query: 482 D--EGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSI 309 D + L + + ++A G V + D + H V SL + G Sbjct: 655 DFTSQIFSLGYCPTGEWLAVGMESSNVEVLHVNKPDKYQLHL-HESCVLSLKFAYCGKWF 713 Query: 308 VSVSTD 291 VS D Sbjct: 714 VSTGKD 719
>TLE1_HUMAN (Q04724) Transducin-like enhancer protein 1 (ESG1) (E(Sp1) homolog)| Length = 770 Score = 49.3 bits (116), Expect = 1e-05 Identities = 30/93 (32%), Positives = 41/93 (44%), Gaps = 3/93 (3%) Frame = -2 Query: 536 TLIIWDLARQAIRSTCEHDEGVTC---LAWLGSSRYVASGCIDGMVRIWDSLSGDLARTF 366 TL IWDLA R E LA S+ S C DG + +WD + L R F Sbjct: 553 TLSIWDLAAPTPRIKAELTSSAPACYALAISPDSKVCFSCCSDGNIAVWDLHNQTLVRQF 612 Query: 365 SGHRDVVQSLAVSADGNSIVSVSTDKSARVFDI 267 GH D + +S DG + + D + R +D+ Sbjct: 613 QGHTDGASCIDISNDGTKLWTGGLDNTVRSWDL 645 Score = 35.8 bits (81), Expect = 0.12 Identities = 31/126 (24%), Positives = 52/126 (41%), Gaps = 2/126 (1%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCEH 483 ++ + +++ +V GHT+ CI IS+ + TG +D T+ WDL R +H Sbjct: 597 NIAVWDLHNQTLVRQFQGHTDGASCIDISNDGTKLWTGGLDNTVRSWDLREG--RQLQQH 654 Query: 482 D--EGVTCLAWLGSSRYVASGCIDGMVRIWDSLSGDLARTFSGHRDVVQSLAVSADGNSI 309 D + L + + ++A G V + D + H V SL + G Sbjct: 655 DFTSQIFSLGYCPTGEWLAVGMESSNVEVLHVNKPDKYQLHL-HESCVLSLKFAYCGKWF 713 Query: 308 VSVSTD 291 VS D Sbjct: 714 VSTGKD 719
>TLE4_RAT (Q07141) Transducin-like enhancer protein 4 (ESP2 protein)| Length = 741 Score = 49.3 bits (116), Expect = 1e-05 Identities = 30/93 (32%), Positives = 41/93 (44%), Gaps = 3/93 (3%) Frame = -2 Query: 536 TLIIWDLARQAIRSTCEHDEGVTC---LAWLGSSRYVASGCIDGMVRIWDSLSGDLARTF 366 TL IWDLA R E LA S+ S C DG + +WD + L R F Sbjct: 524 TLSIWDLAAPTPRIKAELTSSAPACYALAISPDSKVCFSCCSDGNIAVWDLHNQTLVRQF 583 Query: 365 SGHRDVVQSLAVSADGNSIVSVSTDKSARVFDI 267 GH D + +S DG + + D + R +D+ Sbjct: 584 QGHTDGASCIDISNDGTKLWTGGLDNTVRSWDL 616 Score = 34.7 bits (78), Expect = 0.26 Identities = 22/89 (24%), Positives = 42/89 (47%), Gaps = 2/89 (2%) Frame = -2 Query: 662 SVHIVSINSGQVVGSLVGHTNSIECIGISSRYNWVATGSIDRTLIIWDLARQAIRSTCEH 483 ++ + +++ +V GHT+ CI IS+ + TG +D T+ WDL R +H Sbjct: 568 NIAVWDLHNQTLVRQFQGHTDGASCIDISNDGTKLWTGGLDNTVRSWDLREG--RQLQQH 625 Query: 482 D--EGVTCLAWLGSSRYVASGCIDGMVRI 402 D + L + + ++A G + V + Sbjct: 626 DFTSQIFSLGYCPTGEWLAVGMENSNVEV 654 Score = 32.7 bits (73), Expect = 1.00 Identities = 16/54 (29%), Positives = 25/54 (46%), Gaps = 1/54 (1%) Frame = -2 Query: 542 DRTLIIWDLARQA-IRSTCEHDEGVTCLAWLGSSRYVASGCIDGMVRIWDSLSG 384 D + +WDL Q +R H +G +C+ + +G +D VR WD G Sbjct: 566 DGNIAVWDLHNQTLVRQFQGHTDGASCIDISNDGTKLWTGGLDNTVRSWDLREG 619 Database: uniprot_sprot.fasta Posted date: May 25, 2006 5:36 PM Number of letters in database: 80,573,946 Number of sequences in database: 219,361 Lambda K H 0.318 0.135 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 101,754,629 Number of Sequences: 219361 Number of extensions: 2169617 Number of successful extensions: 10746 Number of sequences better than 10.0: 500 Number of HSP's better than 10.0 without gapping: 7519 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 9500 length of database: 80,573,946 effective HSP length: 108 effective length of database: 56,882,958 effective search space used: 6370891296 frameshift window, decay const: 50, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
