>GYP7_YARLI (P09379) GTPase-activating protein GYP7 (GAP for YPT7)|
          Length = 730

 Score = 70.5 bits (171), Expect(2) = 2e-14
 Identities = 45/175 (25%), Positives = 82/175 (46%), Gaps = 1/175 (0%)
 Frame = -2

Query: 631 VLEEDDEAFWCFAGFMRKARHNFRLDEVGIRRQLNMVSKIIKTKDFHLYRHLEMLEAADC 452
           VL++D  AFW F+ FM +   N+  D+ G+R QL  +  +++     LY+HLE  E+ + 
Sbjct: 529 VLQDDTLAFWAFSAFMERMERNYLRDQSGMRNQLLCLDHLVQFMLPSLYKHLEKTESTNL 588

Query: 451 XXXXXXXXXXXXRELTFEQTLSLWEVMWADQAARRAGITRSSWGKLRLGAPPTDDLLLYA 272
                       REL ++  L LWEV+W D  + +                      +  
Sbjct: 589 FFFFRMLLVWFKRELLWDDVLRLWEVLWTDYLSSQ---------------------FVLF 627

Query: 271 IAASVLEKRK-LIIESYSSMDEIIRDCNSMAGQLDIWKLLDDAHDLVVTVQDRIE 110
           +  ++L+K K ++I+  +  DEI++  N ++  +D+ +LL  A  L    +  +E
Sbjct: 628 VCLAILDKHKDVMIDHLAGFDEILKYMNELSMTIDLDELLVRAELLFYRFRRTVE 682



 Score = 28.5 bits (62), Expect(2) = 2e-14
 Identities = 11/18 (61%), Positives = 15/18 (83%)
 Frame = -1

Query: 692 YDPEIGYCQGMSDLLAPL 639
           ++  +GY QGMSDLL+PL
Sbjct: 509 HNKNLGYVQGMSDLLSPL 526

>TBC15_HUMAN (Q8TC07) TBC1 domain family member 15|
          Length = 691

 Score = 60.5 bits (145), Expect(2) = 1e-12
 Identities = 43/161 (26%), Positives = 72/161 (44%)
 Frame = -2

Query: 637 LAVLEEDDEAFWCFAGFMRKARHNFRLDEVGIRRQLNMVSKIIKTKDFHLYRHLEMLEAA 458
           L V+E + +AFWCFA +M +   NF     G++ QL  +S +++  D     +LE  ++ 
Sbjct: 464 LYVMENEVDAFWCFASYMDQMHQNFEEQMQGMKTQLIQLSTLLRLLDSGFCSYLESQDSG 523

Query: 457 DCXXXXXXXXXXXXRELTFEQTLSLWEVMWADQAARRAGITRSSWGKLRLGAPPTDDLLL 278
                         RE  F   L LWEVMW +                    P T+  LL
Sbjct: 524 YLYFCFRWLLIRFKREFGFLDILRLWEVMWTE-------------------LPCTNFHLL 564

Query: 277 YAIAASVLEKRKLIIESYSSMDEIIRDCNSMAGQLDIWKLL 155
              A    EK++ I+E +   +EI++  N ++ ++D+  +L
Sbjct: 565 LCCAILESEKQQ-IMEKHYGFNEILKHINELSMKIDVEDIL 604



 Score = 32.0 bits (71), Expect(2) = 1e-12
 Identities = 13/18 (72%), Positives = 16/18 (88%)
 Frame = -1

Query: 692 YDPEIGYCQGMSDLLAPL 639
           YD ++GY QGMSDLL+PL
Sbjct: 446 YDFDLGYVQGMSDLLSPL 463

>TBC15_MOUSE (Q9CXF4) TBC1 domain family member 15|
          Length = 671

 Score = 59.3 bits (142), Expect(2) = 3e-12
 Identities = 42/161 (26%), Positives = 74/161 (45%)
 Frame = -2

Query: 637 LAVLEEDDEAFWCFAGFMRKARHNFRLDEVGIRRQLNMVSKIIKTKDFHLYRHLEMLEAA 458
           L V+E + +AFWCFA +M +   NF     G++ QL  +S +++  D     +LE  ++ 
Sbjct: 447 LYVMENEVDAFWCFASYMDQMHQNFEEQMQGMKTQLIQLSTLLRLLDSGFCSYLESQDSG 506

Query: 457 DCXXXXXXXXXXXXRELTFEQTLSLWEVMWADQAARRAGITRSSWGKLRLGAPPTDDLLL 278
                         RE +F   L LWEVMW +   +   +                 LL 
Sbjct: 507 YLYFCFRWLLIRFKREFSFLDILRLWEVMWTELPCKNFHL-----------------LLC 549

Query: 277 YAIAASVLEKRKLIIESYSSMDEIIRDCNSMAGQLDIWKLL 155
            AI  S  EK++++ + Y   +EI++  N ++ ++D+  +L
Sbjct: 550 CAILES--EKQQIMAKHY-GFNEILKHINELSMKIDVEDIL 587



 Score = 32.0 bits (71), Expect(2) = 3e-12
 Identities = 13/18 (72%), Positives = 16/18 (88%)
 Frame = -1

Query: 692 YDPEIGYCQGMSDLLAPL 639
           YD ++GY QGMSDLL+PL
Sbjct: 429 YDFDLGYVQGMSDLLSPL 446

>GYP7_DEBHA (Q6BU76) GTPase-activating protein GYP7 (GAP for YPT7)|
          Length = 757

 Score = 61.2 bits (147), Expect(2) = 2e-11
 Identities = 41/189 (21%), Positives = 87/189 (46%)
 Frame = -2

Query: 625  EEDDEAFWCFAGFMRKARHNFRLDEVGIRRQLNMVSKIIKTKDFHLYRHLEMLEAADCXX 446
            +++   FW F  FM +   NF  D+ G++ Q+  ++++++     L++HLE  E+ D   
Sbjct: 552  QDESLTFWAFVNFMDRMERNFLRDQSGMKNQMLTLNELVQFMLPDLFKHLEKCESTDLYF 611

Query: 445  XXXXXXXXXXRELTFEQTLSLWEVMWADQAARRAGITRSSWGKLRLGAPPTDDLLLYAIA 266
                      RE  +   LSLWE++W D  +          G+           L +A+A
Sbjct: 612  FFRMLLVWFKREFEWSSVLSLWEILWTDYYS----------GQFH---------LFFALA 652

Query: 265  ASVLEKRKLIIESYSSMDEIIRDCNSMAGQLDIWKLLDDAHDLVVTVQDRIE*LGSTHAY 86
              + +  ++I ++ S  DE+++  N ++  +++  LL  A  L +  +  I+ +   ++ 
Sbjct: 653  V-LSDNERIIRQNLSRFDEVLKYMNDLSMNMNLNHLLIRAELLFLRFRRMIDIIDRENSL 711

Query: 85   ICMIGPGSF 59
              +  PG +
Sbjct: 712  KKLNNPGVY 720



 Score = 26.9 bits (58), Expect(2) = 2e-11
 Identities = 10/18 (55%), Positives = 15/18 (83%)
 Frame = -1

Query: 692 YDPEIGYCQGMSDLLAPL 639
           ++  +GY QGM+DLL+PL
Sbjct: 530 HNVNLGYVQGMTDLLSPL 547

>TBC17_MOUSE (Q8BYH7) TBC1 domain family member 17|
          Length = 645

 Score = 58.2 bits (139), Expect(2) = 7e-11
 Identities = 43/167 (25%), Positives = 71/167 (42%)
 Frame = -2

Query: 637 LAVLEEDDEAFWCFAGFMRKARHNFRLDEVGIRRQLNMVSKIIKTKDFHLYRHLEMLEAA 458
           L V++ + +AFWCF GFM     NF   +  ++RQL  +  +++  D  L   L+  ++ 
Sbjct: 428 LFVVQNEVDAFWCFCGFMELVHGNFEESQETMKRQLGQLLLLLRVLDQPLCDFLDSQDSG 487

Query: 457 DCXXXXXXXXXXXXRELTFEQTLSLWEVMWADQAARRAGITRSSWGKLRLGAPPTDDLLL 278
                         RE  F   L LWEV+W                    G P  +  LL
Sbjct: 488 SLCFCFRWLLIWFKREFPFPDVLRLWEVLWT-------------------GLPGPNLHLL 528

Query: 277 YAIAASVLEKRKLIIESYSSMDEIIRDCNSMAGQLDIWKLLDDAHDL 137
            A A   +E+  L++  + S +EI++  N +  +L +  +L  A  L
Sbjct: 529 VACAILDMERDTLMLSGFGS-NEILKHINELTMKLSVEDVLTRAEAL 574



 Score = 28.5 bits (62), Expect(2) = 7e-11
 Identities = 11/18 (61%), Positives = 15/18 (83%)
 Frame = -1

Query: 692 YDPEIGYCQGMSDLLAPL 639
           Y  ++GY QGMSDLL+P+
Sbjct: 410 YHFDLGYVQGMSDLLSPI 427

>TBC17_HUMAN (Q9HA65) TBC1 domain family member 17|
          Length = 648

 Score = 57.8 bits (138), Expect(2) = 9e-11
 Identities = 43/167 (25%), Positives = 72/167 (43%)
 Frame = -2

Query: 637 LAVLEEDDEAFWCFAGFMRKARHNFRLDEVGIRRQLNMVSKIIKTKDFHLYRHLEMLEAA 458
           L V++ + +AFWCF GFM   + NF   +  ++RQL  +  +++  D  L   L+  ++ 
Sbjct: 428 LYVIQNEVDAFWCFCGFMELVQGNFEESQETMKRQLGRLLLLLRVLDPLLCDFLDSQDSG 487

Query: 457 DCXXXXXXXXXXXXRELTFEQTLSLWEVMWADQAARRAGITRSSWGKLRLGAPPTDDLLL 278
                         RE  F   L LWEV+W                    G P  +  LL
Sbjct: 488 SLCFCFRWLLIWFKREFPFPDVLRLWEVLWT-------------------GLPGPNLHLL 528

Query: 277 YAIAASVLEKRKLIIESYSSMDEIIRDCNSMAGQLDIWKLLDDAHDL 137
            A A   +E+  L++  + S +EI++  N +  +L +  +L  A  L
Sbjct: 529 VACAILDMERDTLMLSGFGS-NEILKHINELTMKLSVEDVLTRAEAL 574



 Score = 28.5 bits (62), Expect(2) = 9e-11
 Identities = 11/18 (61%), Positives = 15/18 (83%)
 Frame = -1

Query: 692 YDPEIGYCQGMSDLLAPL 639
           Y  ++GY QGMSDLL+P+
Sbjct: 410 YHFDLGYVQGMSDLLSPI 427

>GYP7_CANGA (Q6FWI1) GTPase-activating protein GYP7 (GAP for YPT7)|
          Length = 745

 Score = 52.0 bits (123), Expect(2) = 9e-10
 Identities = 23/90 (25%), Positives = 44/90 (48%)
 Frame = -2

Query: 631 VLEEDDEAFWCFAGFMRKARHNFRLDEVGIRRQLNMVSKIIKTKDFHLYRHLEMLEAADC 452
           ++ +++  FWCF  FM +   NF  D+ GIR Q+  ++ + +     L  HL+  +++D 
Sbjct: 533 IIRDEETTFWCFTNFMERMERNFLRDQSGIRDQMLALTDLCQLMLPRLSAHLQKCDSSDL 592

Query: 451 XXXXXXXXXXXXRELTFEQTLSLWEVMWAD 362
                       RE  ++   ++WEV + D
Sbjct: 593 FFCFRMLLVWFKREFNYDDIFNIWEVFFTD 622



 Score = 30.8 bits (68), Expect(2) = 9e-10
 Identities = 11/18 (61%), Positives = 16/18 (88%)
 Frame = -1

Query: 692 YDPEIGYCQGMSDLLAPL 639
           ++P +GY QGM+DLL+PL
Sbjct: 513 FNPNLGYVQGMTDLLSPL 530

>GYP7_YEAST (P48365) GTPase-activating protein GYP7 (GAP for YPT7)|
          Length = 746

 Score = 47.8 bits (112), Expect(2) = 7e-08
 Identities = 31/154 (20%), Positives = 62/154 (40%)
 Frame = -2

Query: 631 VLEEDDEAFWCFAGFMRKARHNFRLDEVGIRRQLNMVSKIIKTKDFHLYRHLEMLEAADC 452
           +++E+ + FWCF  FM     NF  D+ GI  Q+  + ++++     L  HL   ++ + 
Sbjct: 543 IMKEEWKTFWCFTHFMDIMERNFLRDQSGIHEQMLTLVELVQLMLPELSEHLNKCDSGNL 602

Query: 451 XXXXXXXXXXXXRELTFEQTLSLWEVMWADQAARRAGITRSSWGKLRLGAPPTDDLLLYA 272
                       RE   E  + +WE  W                        +    L+ 
Sbjct: 603 FFCFRMLLVWFKREFEMEDIMHIWENFWTFYY--------------------SSQFQLFF 642

Query: 271 IAASVLEKRKLIIESYSSMDEIIRDCNSMAGQLD 170
           + A + +  + I++  +  D+I++  N + G+LD
Sbjct: 643 MLAILQKNSQAILQHLNQFDQILKFFNELNGKLD 676



 Score = 28.5 bits (62), Expect(2) = 7e-08
 Identities = 10/18 (55%), Positives = 15/18 (83%)
 Frame = -1

Query: 692 YDPEIGYCQGMSDLLAPL 639
           Y+  +GY QGM+DLL+P+
Sbjct: 523 YNTNLGYVQGMTDLLSPI 540

>TBC16_HUMAN (Q8TBP0) TBC1 domain family member 16|
          Length = 767

 Score = 34.7 bits (78), Expect(2) = 3e-05
 Identities = 21/93 (22%), Positives = 38/93 (40%), Gaps = 2/93 (2%)
 Frame = -2

Query: 637 LAVLEEDDEAFWCFAGFMRKARHNFRLDEVGIRRQLNMVSKIIKTKDFHLYRHLEML--E 464
           LA + ++ + FWCF G M+         +  + +QL  + ++++      Y+HL  L  +
Sbjct: 541 LAEVLDESDTFWCFVGLMQNTIFVSSPRDEDMEKQLLYLRELLRLTHVRFYQHLVSLGED 600

Query: 463 AADCXXXXXXXXXXXXRELTFEQTLSLWEVMWA 365
                           RE    + L +WE  WA
Sbjct: 601 GLQMLFCHRWLLLCFKREFPEAEALRIWEACWA 633



 Score = 32.7 bits (73), Expect(2) = 3e-05
 Identities = 12/18 (66%), Positives = 16/18 (88%)
 Frame = -1

Query: 692 YDPEIGYCQGMSDLLAPL 639
           Y+P +GY QGMSDL+AP+
Sbjct: 523 YNPAVGYSQGMSDLVAPI 540

>TBCD2_HUMAN (Q9BYX2) TBC1 domain family member 2 (Prostate antigen recognized|
           and indentified by SEREX) (PARIS-1)
          Length = 917

 Score = 27.3 bits (59), Expect(2) = 0.71
 Identities = 9/20 (45%), Positives = 14/20 (70%)
 Frame = -2

Query: 643 LSLAVLEEDDEAFWCFAGFM 584
           ++L VLEE++ AFWC    +
Sbjct: 721 IALLVLEEEESAFWCLVAIV 740



 Score = 24.6 bits (52), Expect(2) = 0.71
 Identities = 9/15 (60%), Positives = 12/15 (80%)
 Frame = -1

Query: 689 DPEIGYCQGMSDLLA 645
           +P IGYCQG++ L A
Sbjct: 706 NPTIGYCQGLNRLAA 720

>EZA1_ARATH (Q9ZSM8) Probable Polycomb group protein EZA1 (CURLY LEAF-like 1)|
           (Protein SET DOMAIN GROUP 10)
          Length = 856

 Score = 32.7 bits (73), Expect = 1.1
 Identities = 14/34 (41%), Positives = 19/34 (55%)
 Frame = +2

Query: 254 QYTGCNCIQQQVICRRGSKPKFSPGRSCDPSTPR 355
           ++ GC+C + Q  CR    P F+ GR CDP   R
Sbjct: 643 RFRGCHCAKSQ--CRSRQCPCFAAGRECDPDVCR 674

>TSP1_XENLA (P35448) Thrombospondin-1 precursor|
          Length = 1173

 Score = 28.5 bits (62), Expect(2) = 2.4
 Identities = 16/39 (41%), Positives = 21/39 (53%), Gaps = 1/39 (2%)
 Frame = +1

Query: 472 SPGACKDGSPWFLLSWRPC*VACGYPL-RRV*SCGGLSS 585
           S  A  D SPW    W PC V CG+ + +R  SC  L++
Sbjct: 378 SDSADDDWSPWS--DWTPCSVTCGHGIQQRGRSCDSLNN 414



 Score = 21.6 bits (44), Expect(2) = 2.4
 Identities = 12/36 (33%), Positives = 14/36 (38%), Gaps = 3/36 (8%)
 Frame = +2

Query: 260 TGCNCIQQQVICRRGSKPKFSPGRSCDPS---TPRC 358
           T C C     ICR+ S P      +  P     PRC
Sbjct: 340 TECTCQNSATICRKVSCPLMPCTNATIPDGECCPRC 375

>EZ1_MAIZE (Q8S4P6) Polycomb protein EZ1 (Enhancer of zeste protein 1)|
          Length = 931

 Score = 31.6 bits (70), Expect = 2.5
 Identities = 15/39 (38%), Positives = 21/39 (53%), Gaps = 1/39 (2%)
 Frame = +2

Query: 254 QYTGCNCIQQQVICRRGSKPKFSPGRSCDPSTPR-CLIG 367
           ++ GC+C + Q  CR    P F+  R CDP   R C +G
Sbjct: 713 RFRGCHCAKSQ--CRSRQCPCFAADRECDPDVCRNCWVG 749

>COS10_YEAST (P52924) Protein COS10|
          Length = 374

 Score = 30.4 bits (67), Expect = 5.5
 Identities = 17/51 (33%), Positives = 24/51 (47%)
 Frame = -3

Query: 180 GSWTFGSSWTTPMI*W*PYKTGSSSWDLPMLISV*LVLVAFTLSHVCYIQY 28
           G W +  SW    + W      +S+W  P+L SV L+L    +  V  IQY
Sbjct: 41  GFWIWSLSWLPLAVWW----GMASTWFYPLLTSVVLILALIAILPVVQIQY 87

>EZ2_MAIZE (Q8S4P5) Polycomb protein EZ2 (Enhancer of zeste protein 2)|
          Length = 894

 Score = 30.4 bits (67), Expect = 5.5
 Identities = 13/34 (38%), Positives = 18/34 (52%)
 Frame = +2

Query: 254 QYTGCNCIQQQVICRRGSKPKFSPGRSCDPSTPR 355
           ++ GC+C + Q  CR    P F+  R CDP   R
Sbjct: 681 KFRGCHCAKSQ--CRSRQCPCFAASRECDPDVCR 712

>EZ3_MAIZE (Q8S4P4) Polycomb protein EZ3 (Enhancer of zeste protein 3)|
          Length = 895

 Score = 30.4 bits (67), Expect = 5.5
 Identities = 13/34 (38%), Positives = 18/34 (52%)
 Frame = +2

Query: 254 QYTGCNCIQQQVICRRGSKPKFSPGRSCDPSTPR 355
           ++ GC+C + Q  CR    P F+  R CDP   R
Sbjct: 682 KFRGCHCAKSQ--CRSRQCPCFAASRECDPDVCR 713

>ATU_DROME (Q94546) Another transcription unit protein|
          Length = 725

 Score = 30.0 bits (66), Expect = 7.2
 Identities = 14/36 (38%), Positives = 21/36 (58%)
 Frame = -1

Query: 563 QTRRSGYPQATQHGLQDNKNQGLPSLQAPGDARSRR 456
           Q+RRSG PQ+ + G   ++  G    +  G ARSR+
Sbjct: 125 QSRRSGSPQSRKSGSTHSRRSGSAHSRRSGSARSRK 160



 Score = 30.0 bits (66), Expect = 7.2
 Identities = 14/37 (37%), Positives = 21/37 (56%)
 Frame = -1

Query: 566 LQTRRSGYPQATQHGLQDNKNQGLPSLQAPGDARSRR 456
           LQ+R+SG PQ+ + G   ++  G    +  G A SRR
Sbjct: 116 LQSRKSGSPQSRRSGSPQSRKSGSTHSRRSGSAHSRR 152

>CLF_ARATH (P93831) Polycomb group protein CURLY LEAF (Protein INCURVATA 1)|
           (Protein photoperiod insensitive flowering) (Protein SET
           DOMAIN GROUP 1)
          Length = 902

 Score = 30.0 bits (66), Expect = 7.2
 Identities = 13/34 (38%), Positives = 18/34 (52%)
 Frame = +2

Query: 254 QYTGCNCIQQQVICRRGSKPKFSPGRSCDPSTPR 355
           ++ GC+C + Q  CR    P F+  R CDP   R
Sbjct: 687 RFRGCHCAKSQ--CRSRQCPCFAADRECDPDVCR 718

>ADA1D_RAT (P23944) Alpha-1D adrenergic receptor (Alpha 1D-adrenoceptor)|
           (Alpha 1D-adrenoreceptor) (Alpha-1A adrenergic receptor)
           (RA42)
          Length = 561

 Score = 29.6 bits (65), Expect = 9.4
 Identities = 24/81 (29%), Positives = 33/81 (40%)
 Frame = +2

Query: 452 AVCGFEHLQVPVKMEVLGFYYLGDHVELPADTHFVESEVVAGFPHETGKAPEGFIVFLQH 631
           +VC F      + M V+   Y   +V   + T  +E    AG   E GKA E  +V   H
Sbjct: 253 SVCSFY-----LPMAVIVVMYCRVYVVARSTTRSLE----AGIKREPGKASE--VVLRIH 301

Query: 632 SKGEVQGGRSCPGNSQFLGHT 694
            +G     +  PG     GHT
Sbjct: 302 CRGAATSAKGYPGTQSSKGHT 322

>SCRL4_ARATH (P82623) Protein SCRL4 precursor|
          Length = 97

 Score = 29.6 bits (65), Expect = 9.4
 Identities = 14/42 (33%), Positives = 20/42 (47%)
 Frame = -1

Query: 389 QPVGGDVGRSGSEACWDHKIVLGKTSAWSPSDR*PAAVCNCS 264
           Q  GG  G  G++ C ++ +     S W PS R     CNC+
Sbjct: 44  QVFGGSCGNDGAQQCLNNLL-----STWDPSVRLSPVSCNCT 80


  Database: uniprot_sprot.fasta
    Posted date:  May 25, 2006  5:36 PM
  Number of letters in database: 80,573,946
  Number of sequences in database:  219,361
  
Lambda     K      H
   0.318    0.135    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 115,808,132
Number of Sequences: 219361
Number of extensions: 2754635
Number of successful extensions: 6940
Number of sequences better than 10.0: 20
Number of HSP's better than 10.0 without gapping: 6496
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 6927
length of database: 80,573,946
effective HSP length: 109
effective length of database: 56,663,597
effective search space used: 7082949625
frameshift window, decay const: 50,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)