Clone Name	bags9l16
Clone Library Name	barley_pub

---

No.	Definition	Score (bits)	E Value
1	PUR9_LISMO (Q8Y6C5) Bifunctional purine biosynthesis protein pur...	195	7e-50
2	PUR9_BACHD (Q9KF53) Bifunctional purine biosynthesis protein pur...	194	2e-49
3	PUR9_LISMF (Q71YQ3) Bifunctional purine biosynthesis protein pur...	194	2e-49
4	PUR9_LISIN (Q92AP3) Bifunctional purine biosynthesis protein pur...	192	5e-49
5	PUR9_BACSU (P12048) Bifunctional purine biosynthesis protein pur...	192	8e-49
6	PUR9_OCEIH (Q8CXK7) Bifunctional purine biosynthesis protein pur...	191	1e-48
7	PUR9_RALSO (Q8Y232) Bifunctional purine biosynthesis protein pur...	188	1e-47
8	PUR9_STRSU (Q9F1T4) Bifunctional purine biosynthesis protein pur...	184	2e-46
9	PUR9_BRAJA (Q89WU7) Bifunctional purine biosynthesis protein pur...	182	5e-46
10	PUR9_THETN (Q8RC55) Bifunctional purine biosynthesis protein pur...	181	2e-45
11	PUR9_STRR6 (Q8DRM1) Bifunctional purine biosynthesis protein pur...	180	3e-45
12	PUR9_STRMU (Q8DWK8) Bifunctional purine biosynthesis protein pur...	179	7e-45
13	PUR9_STRA5 (P67546) Bifunctional purine biosynthesis protein pur...	178	9e-45
14	PUR9_STRA3 (P67545) Bifunctional purine biosynthesis protein pur...	178	9e-45
15	PUR9_STRP6 (Q5XEF2) Bifunctional purine biosynthesis protein pur...	177	2e-44
16	PUR9_NEIMA (Q9JUQ8) Bifunctional purine biosynthesis protein pur...	177	3e-44
17	PUR9_STRP3 (Q8K8Y6) Bifunctional purine biosynthesis protein pur...	177	3e-44
18	PUR9_STRPN (Q97T99) Bifunctional purine biosynthesis protein pur...	176	3e-44
19	PUR9_LACPL (Q88U29) Bifunctional purine biosynthesis protein pur...	176	4e-44
20	PUR9_STRP8 (Q8P310) Bifunctional purine biosynthesis protein pur...	176	6e-44
21	PUR9_YERPE (Q8ZAR3) Bifunctional purine biosynthesis protein pur...	175	7e-44
22	PUR9_CLOPE (Q8XMK2) Bifunctional purine biosynthesis protein pur...	175	7e-44
23	PUR9_CLOAB (Q97J91) Bifunctional purine biosynthesis protein pur...	175	7e-44
24	PUR9_NEIMB (Q9JZM7) Bifunctional purine biosynthesis protein pur...	174	2e-43
25	PUR9_CLOTE (Q892X3) Bifunctional purine biosynthesis protein pur...	174	2e-43
26	PUR9_CAUCR (Q9ABY4) Bifunctional purine biosynthesis protein pur...	174	2e-43
27	PUR9_VIBF1 (Q5E257) Bifunctional purine biosynthesis protein pur...	173	4e-43
28	PUR9_LACLA (Q9CFG0) Bifunctional purine biosynthesis protein pur...	172	6e-43
29	PUR9_SALTY (P26978) Bifunctional purine biosynthesis protein pur...	172	8e-43
30	PUR9_RHOBA (Q7UKJ8) Bifunctional purine biosynthesis protein pur...	172	8e-43
31	PUR9_ECO57 (Q8X611) Bifunctional purine biosynthesis protein pur...	171	1e-42
32	PUR9_STRCO (Q9KY50) Bifunctional purine biosynthesis protein pur...	171	1e-42
33	PUR9_ECOLI (P15639) Bifunctional purine biosynthesis protein pur...	171	2e-42
34	PUR9_LEPIN (Q8F3W6) Bifunctional purine biosynthesis protein pur...	170	3e-42
35	PUR9_LEPIC (Q72RT5) Bifunctional purine biosynthesis protein pur...	170	3e-42
36	PUR9_SALTI (Q8Z335) Bifunctional purine biosynthesis protein pur...	169	4e-42
37	PUR9_VIBPA (Q87KT0) Bifunctional purine biosynthesis protein pur...	169	5e-42
38	PUR9_BRUSU (P67540) Bifunctional purine biosynthesis protein pur...	169	7e-42
39	PUR9_BRUME (P67539) Bifunctional purine biosynthesis protein pur...	169	7e-42
40	PUR9_MYCTU (P67541) Bifunctional purine biosynthesis protein pur...	169	7e-42
41	PUR9_MYCBO (P67542) Bifunctional purine biosynthesis protein pur...	169	7e-42
42	PUR9_FUSNN (Q8REV6) Bifunctional purine biosynthesis protein pur...	169	7e-42
43	PUR9_STAES (Q8CT27) Bifunctional purine biosynthesis protein pur...	168	9e-42
44	PUR9_STAEQ (Q5HQ97) Bifunctional purine biosynthesis protein pur...	168	9e-42
45	PUR9_ECOL6 (Q8FB68) Bifunctional purine biosynthesis protein pur...	167	2e-41
46	PUR9_AGRT5 (Q8UBM8) Bifunctional purine biosynthesis protein pur...	167	2e-41
47	PUR9_DEIRA (Q9RW01) Bifunctional purine biosynthesis protein pur...	167	2e-41
48	PUR9_SYNEL (Q8DIN5) Bifunctional purine biosynthesis protein pur...	167	2e-41
49	PUR9_AQUAE (O67775) Bifunctional purine biosynthesis protein pur...	167	2e-41
50	PUR9_COREF (Q8FR29) Bifunctional purine biosynthesis protein pur...	167	2e-41
51	PUR9_VIBCH (Q9KV80) Bifunctional purine biosynthesis protein pur...	166	3e-41
52	PUR9_STAAW (Q8NX88) Bifunctional purine biosynthesis protein pur...	166	6e-41
53	PUR9_STAAS (Q6GAE0) Bifunctional purine biosynthesis protein pur...	166	6e-41
54	PUR9_STAAR (Q6GI11) Bifunctional purine biosynthesis protein pur...	166	6e-41
55	PUR9_STAAC (Q5HH11) Bifunctional purine biosynthesis protein pur...	166	6e-41
56	PUR9_VIBVY (Q7MGT5) Bifunctional purine biosynthesis protein pur...	166	6e-41
57	PUR9_VIBVU (Q8DD06) Bifunctional purine biosynthesis protein pur...	166	6e-41
58	PUR9_STAAN (P67544) Bifunctional purine biosynthesis protein pur...	165	8e-41
59	PUR9_STAAM (P67543) Bifunctional purine biosynthesis protein pur...	165	8e-41
60	PUR9_PASMU (P57828) Bifunctional purine biosynthesis protein pur...	164	2e-40
61	PUR9_BIFLO (Q8G6B1) Bifunctional purine biosynthesis protein pur...	164	2e-40
62	PUR9_MYCLE (Q9Z5H5) Bifunctional purine biosynthesis protein pur...	164	2e-40
63	PUR9_MYCPA (Q9RAJ5) Bifunctional purine biosynthesis protein pur...	163	3e-40
64	PUR9_RHIME (Q92KX6) Bifunctional purine biosynthesis protein pur...	163	3e-40
65	PUR9_PSEAE (Q9HUV9) Bifunctional purine biosynthesis protein pur...	163	4e-40
66	PUR9_PSEPK (Q88DK3) Bifunctional purine biosynthesis protein pur...	162	5e-40
67	PUR9_CAMJR (Q5HUK6) Bifunctional purine biosynthesis protein pur...	162	7e-40
68	PUR9_HAEIN (P43852) Bifunctional purine biosynthesis protein pur...	162	7e-40
69	PUR9_CORGL (Q8NS21) Bifunctional purine biosynthesis protein pur...	162	9e-40
70	PUR9_PSESM (Q87VR9) Bifunctional purine biosynthesis protein pur...	161	1e-39
71	PUR9_LEIXX (Q6AD62) Bifunctional purine biosynthesis protein pur...	160	2e-39
72	PUR9_CAMJE (Q9PNY2) Bifunctional purine biosynthesis protein pur...	160	3e-39
73	PUR9_SHEON (Q8EJM1) Bifunctional purine biosynthesis protein pur...	159	6e-39
74	PUR9_CORAM (Q9RHX6) Bifunctional purine biosynthesis protein pur...	158	1e-38
75	PUR9_CHLTE (Q8KFK6) Bifunctional purine biosynthesis protein pur...	157	2e-38
76	PUR9_RHILO (Q98ES7) Bifunctional purine biosynthesis protein pur...	155	8e-38
77	PUR9_BUCAP (Q8KA70) Bifunctional purine biosynthesis protein pur...	155	1e-37
78	PUR92_YEAST (P38009) Bifunctional purine biosynthesis protein AD...	153	3e-37
79	PUR9_XANCP (Q8PD47) Bifunctional purine biosynthesis protein pur...	150	2e-36
80	PUR9_XYLFT (Q87D58) Bifunctional purine biosynthesis protein pur...	150	3e-36
81	PUR9_XANAC (Q8PQ19) Bifunctional purine biosynthesis protein pur...	150	3e-36
82	PUR9_XYLFA (Q9PC10) Bifunctional purine biosynthesis protein pur...	148	1e-35
83	PUR9_ANASP (Q8YSJ2) Bifunctional purine biosynthesis protein pur...	147	3e-35
84	PUR91_YEAST (P54113) Bifunctional purine biosynthesis protein AD...	146	4e-35
85	PUR9_BUCAI (P57143) Bifunctional purine biosynthesis protein pur...	143	3e-34
86	PUR9_CHICK (P31335) Bifunctional purine biosynthesis protein PUR...	142	7e-34
87	PUR9_BACTN (Q8A155) Bifunctional purine biosynthesis protein pur...	142	9e-34
88	PUR9_SYNY3 (P74741) Bifunctional purine biosynthesis protein pur...	141	1e-33
89	PUR9_HUMAN (P31939) Bifunctional purine biosynthesis protein PUR...	138	1e-32
90	PUR9_SCHPO (O74928) Bifunctional purine biosynthesis protein ade...	136	5e-32
91	PUR9_MOUSE (Q9CWJ9) Bifunctional purine biosynthesis protein PUR...	134	2e-31
92	PUR9_WIGBR (Q8D244) Bifunctional purine biosynthesis protein pur...	127	3e-29
93	PUR9_BUCBP (Q89B23) Bifunctional purine biosynthesis protein pur...	120	2e-27
94	PUR9_THEMA (Q9X0X6) Bifunctional purine biosynthesis protein pur...	72	2e-12
95	ITB4_RAT (Q64632) Integrin beta-4 precursor (GP150) (CD104 antigen)	35	0.21
96	VP75_SHV21 (P11282) Probable membrane antigen 75 (Tegument protein)	34	0.27
97	GBF_DICDI (P36417) G-box-binding factor (GBF)	33	0.78
98	PHLA1_MOUSE (Q62392) Pleckstrin homology-like domain family A me...	33	0.78
99	ITB4_HUMAN (P16144) Integrin beta-4 precursor (GP150) (CD104 ant...	32	1.7
100	TRPA_STAES (Q8CPB0) Tryptophan synthase alpha chain (EC 4.2.1.20)	31	2.3
101	TRPA_STAEQ (Q5HPG9) Tryptophan synthase alpha chain (EC 4.2.1.20)	31	2.3
102	SAM4_YEAST (Q08985) Homocysteine S-methyltransferase 2 (EC 2.1.1...	31	2.3
103	EF2_SCHPO (O14460) Elongation factor 2 (EF-2)	31	3.0
104	YL766_MIMIV (Q5UPQ2) Putative ankyrin repeat protein L766	30	5.0
105	CAUP_DROME (P54269) Homeobox protein caupolican	30	5.0
106	DOA_DROME (P49762) Serine/threonine-protein kinase Doa (EC 2.7.1...	30	6.6
107	Y143_MYCPN (P75143) Hypothetical protein MPN143 (E07_orf175)	29	8.6
108	CUT1_SCHPO (P18296) Separin (EC 3.4.22.49) (Separase) (Cell unti...	29	8.6
109	VNS1_AHSV6 (P87505) Nonstructural protein NS1	29	8.6

---

>PUR9_LISMO (Q8Y6C5) Bifunctional purine biosynthesis protein purH [Includes:|
           Phosphoribosylaminoimidazolecarboxamide
           formyltransferase (EC 2.1.2.3) (AICAR transformylase);
           IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
           synthetase) (ATIC)]
          Length = 509

 Score =  195 bits (496), Expect = 7e-50
 Identities = 97/186 (52%), Positives = 130/186 (69%), Gaps = 1/186 (0%)
 Frame = +1

Query: 4   AGXNVTKVEQITHFPEMLDGRVKTLHPSIHGGILARRDQEHHLKALNEHGIGTFDVVVVN 183
           AG  VT +E++T FPEMLDGRVKTLHP+IHGG+LARRD   H++A+  H I   D+V+VN
Sbjct: 41  AGVPVTGIEEVTEFPEMLDGRVKTLHPAIHGGLLARRDTAEHMEAIAAHNIKPIDLVIVN 100

Query: 184 LYPFYDKVTSGAISFEDGIENIDIGGPTLIRAAAKNHKDVLVVVDHRDYPALLKYLQEKQ 363
           LYPF + +    ++ E+ IENIDIGGP+++R+AAKN+  V VVVD  DY A+L  LQE  
Sbjct: 101 LYPFQETIQKPGVTLEEAIENIDIGGPSMLRSAAKNYAAVTVVVDTADYDAVLTELQEHG 160

Query: 364 VDP-QFRRMLAWKAFQHVASYDSAVSEWLWKQSNSGDIFPPSFTVPLSMKSTLRYGENPH 540
               + R+ LA K F+H A+YD+ ++E+L   + +G+ FP   T   + K  LRYGENPH
Sbjct: 161 ATTFETRQRLAAKVFRHTAAYDALIAEYL--TNITGETFPEKVTFTYNRKQVLRYGENPH 218

Query: 541 QKAAFY 558
           Q AAFY
Sbjct: 219 QDAAFY 224

---

>PUR9_BACHD (Q9KF53) Bifunctional purine biosynthesis protein purH [Includes:|
           Phosphoribosylaminoimidazolecarboxamide
           formyltransferase (EC 2.1.2.3) (AICAR transformylase);
           IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
           synthetase) (ATIC)]
          Length = 511

 Score =  194 bits (493), Expect = 2e-49
 Identities = 100/186 (53%), Positives = 126/186 (67%), Gaps = 1/186 (0%)
 Frame = +1

Query: 4   AGXNVTKVEQITHFPEMLDGRVKTLHPSIHGGILARRDQEHHLKALNEHGIGTFDVVVVN 183
           AG  VT +  +T FPE+LDGRVKTLHP+IHGG+LA R+++ HL  LNEH I   D VVVN
Sbjct: 42  AGIPVTGISDVTGFPEILDGRVKTLHPNIHGGLLAMRERDEHLAQLNEHHIRPIDFVVVN 101

Query: 184 LYPFYDKVTSGAISFEDGIENIDIGGPTLIRAAAKNHKDVLVVVDHRDYPALLKYLQEK- 360
           LYPF   +     +F D IENIDIGGP+++RAAAKNH+ V VVVD  DY  +LK L ++ 
Sbjct: 102 LYPFQQTIAKPEATFADAIENIDIGGPSMLRAAAKNHQHVTVVVDPVDYETVLKELADQG 161

Query: 361 QVDPQFRRMLAWKAFQHVASYDSAVSEWLWKQSNSGDIFPPSFTVPLSMKSTLRYGENPH 540
            V  + +R LA K F+H A+YD+ ++E+L      G+  P S TV    K  LRYGENPH
Sbjct: 162 NVATETKRRLAAKVFRHTAAYDAMIAEYL--TDAVGEESPESLTVTFEKKQDLRYGENPH 219

Query: 541 QKAAFY 558
           QKA FY
Sbjct: 220 QKATFY 225

---

>PUR9_LISMF (Q71YQ3) Bifunctional purine biosynthesis protein purH [Includes:|
           Phosphoribosylaminoimidazolecarboxamide
           formyltransferase (EC 2.1.2.3) (AICAR transformylase);
           IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
           synthetase) (ATIC)]
          Length = 509

 Score =  194 bits (493), Expect = 2e-49
 Identities = 96/186 (51%), Positives = 130/186 (69%), Gaps = 1/186 (0%)
 Frame = +1

Query: 4   AGXNVTKVEQITHFPEMLDGRVKTLHPSIHGGILARRDQEHHLKALNEHGIGTFDVVVVN 183
           AG  VT +E++T FPEMLDGRVKTLHP+IHGG+LARRD   H++A+  H I   D+VVVN
Sbjct: 41  AGVPVTGIEEVTEFPEMLDGRVKTLHPAIHGGLLARRDTAEHMEAIAAHDIKPIDLVVVN 100

Query: 184 LYPFYDKVTSGAISFEDGIENIDIGGPTLIRAAAKNHKDVLVVVDHRDYPALLKYLQEKQ 363
           LYPF + +    ++ E+ IENIDIGGP+++R+AAKN+  V VVVD  DY  +L  L+E  
Sbjct: 101 LYPFQETIQKSGVTLEEAIENIDIGGPSMLRSAAKNYAAVTVVVDTADYDTVLTELEEHG 160

Query: 364 VDP-QFRRMLAWKAFQHVASYDSAVSEWLWKQSNSGDIFPPSFTVPLSMKSTLRYGENPH 540
               + R+ LA K F+H A+YD+ ++E+L   + +G+ FP   T+  + K  LRYGENPH
Sbjct: 161 ATTFETRQRLAAKVFRHTAAYDALIAEYL--TNITGETFPEKVTLTYNRKQVLRYGENPH 218

Query: 541 QKAAFY 558
           Q AAFY
Sbjct: 219 QDAAFY 224

---

>PUR9_LISIN (Q92AP3) Bifunctional purine biosynthesis protein purH [Includes:|
           Phosphoribosylaminoimidazolecarboxamide
           formyltransferase (EC 2.1.2.3) (AICAR transformylase);
           IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
           synthetase) (ATIC)]
          Length = 509

 Score =  192 bits (489), Expect = 5e-49
 Identities = 96/186 (51%), Positives = 128/186 (68%), Gaps = 1/186 (0%)
 Frame = +1

Query: 4   AGXNVTKVEQITHFPEMLDGRVKTLHPSIHGGILARRDQEHHLKALNEHGIGTFDVVVVN 183
           AG  VT +E +T FPEMLDGRVKTLHP+IHGG+LARRD   H++A+  H I   D+V+VN
Sbjct: 41  AGVPVTGIEAVTEFPEMLDGRVKTLHPAIHGGLLARRDTAEHMEAIAAHDIKPIDLVIVN 100

Query: 184 LYPFYDKVTSGAISFEDGIENIDIGGPTLIRAAAKNHKDVLVVVDHRDYPALLKYLQEKQ 363
           LYPF + +    ++ E+ IENIDIGGP+++R+AAKN+  V VVVD  DY  +L  LQE  
Sbjct: 101 LYPFQETIQKPGVTLEEAIENIDIGGPSMLRSAAKNYAAVTVVVDTADYDTVLTELQEHG 160

Query: 364 VDP-QFRRMLAWKAFQHVASYDSAVSEWLWKQSNSGDIFPPSFTVPLSMKSTLRYGENPH 540
               + R+ LA K F+H A+YD+ ++E+L     +G+ FP   T+  + K  LRYGENPH
Sbjct: 161 ATTFETRQRLAAKVFRHTAAYDALIAEYL--TDVTGETFPEKVTLTYNRKQVLRYGENPH 218

Query: 541 QKAAFY 558
           Q AAFY
Sbjct: 219 QDAAFY 224

---

>PUR9_BACSU (P12048) Bifunctional purine biosynthesis protein purH [Includes:|
           Phosphoribosylaminoimidazolecarboxamide
           formyltransferase (EC 2.1.2.3) (AICAR transformylase);
           IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
           synthetase) (ATIC)]
          Length = 512

 Score =  192 bits (487), Expect = 8e-49
 Identities = 93/185 (50%), Positives = 131/185 (70%), Gaps = 1/185 (0%)
 Frame = +1

Query: 7   GXNVTKVEQITHFPEMLDGRVKTLHPSIHGGILARRDQEHHLKALNEHGIGTFDVVVVNL 186
           G +V  + ++T FPE++DGR+KTLHP+IHGG+LA R  E H+  +NEHGI   D+VVVNL
Sbjct: 44  GVDVIGISEVTGFPEIMDGRLKTLHPNIHGGLLAVRGNEEHMAQINEHGIQPIDLVVVNL 103

Query: 187 YPFYDKVTSGAISFEDGIENIDIGGPTLIRAAAKNHKDVLVVVDHRDY-PALLKYLQEKQ 363
           YPF + ++   +++E+ IENIDIGGP ++RAA+KNH+DV V+VD  DY P L +  +E  
Sbjct: 104 YPFKETISKEDVTYEEAIENIDIGGPGMLRAASKNHQDVTVIVDPADYSPVLNQIKEEGS 163

Query: 364 VDPQFRRMLAWKAFQHVASYDSAVSEWLWKQSNSGDIFPPSFTVPLSMKSTLRYGENPHQ 543
           V  Q +R LA K F+H A+YD+ ++++L   +  G+  P  FTV    K +LRYGENPHQ
Sbjct: 164 VSLQKKRELAAKVFRHTAAYDALIADYL--TNVVGEKEPEQFTVTFEKKQSLRYGENPHQ 221

Query: 544 KAAFY 558
           +A FY
Sbjct: 222 EATFY 226

---

>PUR9_OCEIH (Q8CXK7) Bifunctional purine biosynthesis protein purH [Includes:|
           Phosphoribosylaminoimidazolecarboxamide
           formyltransferase (EC 2.1.2.3) (AICAR transformylase);
           IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
           synthetase) (ATIC)]
          Length = 510

 Score =  191 bits (485), Expect = 1e-48
 Identities = 94/185 (50%), Positives = 126/185 (68%)
 Frame = +1

Query: 4   AGXNVTKVEQITHFPEMLDGRVKTLHPSIHGGILARRDQEHHLKALNEHGIGTFDVVVVN 183
           AG +VT V+++T FPEMLDGRVKTLHP IHGG+L +R    HL  + EHGI + D+V VN
Sbjct: 42  AGIDVTPVDEVTGFPEMLDGRVKTLHPMIHGGLLGKRSNHEHLSQMEEHGIRSIDLVAVN 101

Query: 184 LYPFYDKVTSGAISFEDGIENIDIGGPTLIRAAAKNHKDVLVVVDHRDYPALLKYLQEKQ 363
           LYPF + V    +S +D IENIDIGGP+++R+AAKN +DVLVV    DY  +L  +  + 
Sbjct: 102 LYPFKETVQKPDVSHQDIIENIDIGGPSMLRSAAKNFEDVLVVTGPTDYNRVLAAITSET 161

Query: 364 VDPQFRRMLAWKAFQHVASYDSAVSEWLWKQSNSGDIFPPSFTVPLSMKSTLRYGENPHQ 543
              +FR+ LA K F+H ASYD+ ++ +   Q+   + +P S+TV       LRYGENPHQ
Sbjct: 162 DTYEFRQQLAAKVFRHTASYDAMIANYFLSQTE--EQYPESYTVTYEKVQDLRYGENPHQ 219

Query: 544 KAAFY 558
           +AAFY
Sbjct: 220 QAAFY 224

---

>PUR9_RALSO (Q8Y232) Bifunctional purine biosynthesis protein purH [Includes:|
           Phosphoribosylaminoimidazolecarboxamide
           formyltransferase (EC 2.1.2.3) (AICAR transformylase);
           IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
           synthetase) (ATIC)]
          Length = 524

 Score =  188 bits (477), Expect = 1e-47
 Identities = 97/194 (50%), Positives = 122/194 (62%), Gaps = 7/194 (3%)
 Frame = +1

Query: 4   AGXNVTKVEQITHFPEMLDGRVKTLHPSIHGGILARRDQEHHLKALNEHGIGTFDVVVVN 183
           +G  VT+V   T FPEMLDGRVKTLHP +HGGILARRD   H+ AL++HGI T D++VVN
Sbjct: 42  SGLPVTEVADYTGFPEMLDGRVKTLHPKVHGGILARRDLPEHMAALSQHGIPTIDLLVVN 101

Query: 184 LYPFYDKVTSGAISFEDGIENIDIGGPTLIRAAAKNHKDVLVVVDHRDYPALLKYLQE-- 357
           LYPF   V     +  D IENIDIGGPT++R+AAKNH+DV V+VD  DY  +L  +Q   
Sbjct: 102 LYPFQQTVAKDECTLADAIENIDIGGPTMLRSAAKNHRDVTVIVDPADYATVLAEMQANG 161

Query: 358 KQVDPQFRRMLAWKAFQHVASYDSAVSEWLW-----KQSNSGDIFPPSFTVPLSMKSTLR 522
             V      MLA K F H A YD A++ +L      K  ++   +P +  +       +R
Sbjct: 162 NTVGYDTNFMLAKKVFAHTAQYDGAITNYLTSLGQDKSHSTRSQYPQTLNLAFEQVQEMR 221

Query: 523 YGENPHQKAAFYGD 564
           YGENPHQ AAFY D
Sbjct: 222 YGENPHQSAAFYRD 235

---

>PUR9_STRSU (Q9F1T4) Bifunctional purine biosynthesis protein purH [Includes:|
           Phosphoribosylaminoimidazolecarboxamide
           formyltransferase (EC 2.1.2.3) (AICAR transformylase);
           IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
           synthetase) (ATIC)]
          Length = 515

 Score =  184 bits (467), Expect = 2e-46
 Identities = 89/186 (47%), Positives = 125/186 (67%), Gaps = 1/186 (0%)
 Frame = +1

Query: 4   AGXNVTKVEQITHFPEMLDGRVKTLHPSIHGGILARRDQEHHLKALNEHGIGTFDVVVVN 183
           AG     ++ +T FPEM+DGRVKTLHP IHGG+LARRD + HL+A N+H IG  D+VVVN
Sbjct: 42  AGVTTIAIDDVTGFPEMMDGRVKTLHPKIHGGLLARRDLDSHLQAANDHEIGLIDLVVVN 101

Query: 184 LYPFYDKVTSGAISFEDGIENIDIGGPTLIRAAAKNHKDVLVVVDHRDYPALLKYLQEK- 360
           LYPF + +    ++++  +ENIDIGGP+++R+AAKNH  V VVVD  DYP +L  + E+ 
Sbjct: 102 LYPFKETILRPDVTYDLAVENIDIGGPSMLRSAAKNHASVTVVVDPADYPTVLGEIAEQG 161

Query: 361 QVDPQFRRMLAWKAFQHVASYDSAVSEWLWKQSNSGDIFPPSFTVPLSMKSTLRYGENPH 540
           +     R+ LA K F+H A+YD+ ++++  KQ   G+  P   T+   +   +RYGENP 
Sbjct: 162 ETSYATRQRLAAKVFRHTAAYDALIADYFTKQ--VGEDKPEKLTITYDLNQPMRYGENPQ 219

Query: 541 QKAAFY 558
           Q A FY
Sbjct: 220 QNADFY 225

---

>PUR9_BRAJA (Q89WU7) Bifunctional purine biosynthesis protein purH [Includes:|
           Phosphoribosylaminoimidazolecarboxamide
           formyltransferase (EC 2.1.2.3) (AICAR transformylase);
           IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
           synthetase) (ATIC)]
          Length = 530

 Score =  182 bits (463), Expect = 5e-46
 Identities = 101/189 (53%), Positives = 123/189 (65%), Gaps = 3/189 (1%)
 Frame = +1

Query: 1   AAGXNVTKVEQITHFPEMLDGRVKTLHPSIHGGILARRDQEHHLKALNEHGIGTFDVVVV 180
           AAG  V  V ++T FPEM+DGRVKTLHP +HGG+LA RD + H  A+  HGI   D++VV
Sbjct: 47  AAGLKVKDVSELTGFPEMMDGRVKTLHPKVHGGLLAIRDNKDHADAMKAHGIAPIDLLVV 106

Query: 181 NLYPFYDKVTSGAISFEDGIENIDIGGPTLIRAAAKNHKDVLVVVDHRDYPALLKYLQEK 360
           NLYPF   V  GA  FED IENIDIGGP +IRAAAKNH DV VVV+  DY A+L  L   
Sbjct: 107 NLYPFEATVDKGA-GFEDCIENIDIGGPAMIRAAAKNHDDVAVVVEAEDYKAVLDELAAN 165

Query: 361 Q--VDPQFRRMLAWKAFQHVASYDSAVSEWLWKQSNSGDIFPPSF-TVPLSMKSTLRYGE 531
           +     + RR LA KA+   A+YD+A+S W  +Q    +I  P F      +  +LRYGE
Sbjct: 166 KGATTLKLRRRLAAKAYARTAAYDAAISNWFNRQL---EIDAPDFRAFGGKLIQSLRYGE 222

Query: 532 NPHQKAAFY 558
           NPHQ AAFY
Sbjct: 223 NPHQTAAFY 231

---

>PUR9_THETN (Q8RC55) Bifunctional purine biosynthesis protein purH [Includes:|
           Phosphoribosylaminoimidazolecarboxamide
           formyltransferase (EC 2.1.2.3) (AICAR transformylase);
           IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
           synthetase) (ATIC)]
          Length = 508

 Score =  181 bits (458), Expect = 2e-45
 Identities = 94/186 (50%), Positives = 124/186 (66%), Gaps = 1/186 (0%)
 Frame = +1

Query: 4   AGXNVTKVEQITHFPEMLDGRVKTLHPSIHGGILARRDQEHHLKALNEHGIGTFDVVVVN 183
           +G  V KV ++T FPE++ GRVKTLHP IHGGILA RD++ HLK LN+HGI   D+V +N
Sbjct: 42  SGVKVIKVSEVTGFPEIMGGRVKTLHPKIHGGILAVRDKKEHLKDLNDHGIVPIDLVAIN 101

Query: 184 LYPFYDKVTSGAISFEDGIENIDIGGPTLIRAAAKNHKDVLVVVDHRDYPALLKYLQ-EK 360
           LYPF + ++   ++ E+ IENIDIGGP +IRAAAKN+K V V+VD  DY  +++ ++   
Sbjct: 102 LYPFKETISREKVALEEAIENIDIGGPAMIRAAAKNYKYVTVLVDPVDYEKVIEEIKLYG 161

Query: 361 QVDPQFRRMLAWKAFQHVASYDSAVSEWLWKQSNSGDIFPPSFTVPLSMKSTLRYGENPH 540
               + R  LA KAF H A YDS + E+  +++N    FP   T        LRYGENPH
Sbjct: 162 DTKEETRFYLAAKAFGHTAFYDSLIYEYFREKTNME--FPKVITFAYEKVQDLRYGENPH 219

Query: 541 QKAAFY 558
           QKAAFY
Sbjct: 220 QKAAFY 225

---

>PUR9_STRR6 (Q8DRM1) Bifunctional purine biosynthesis protein purH [Includes:|
           Phosphoribosylaminoimidazolecarboxamide
           formyltransferase (EC 2.1.2.3) (AICAR transformylase);
           IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
           synthetase) (ATIC)]
          Length = 515

 Score =  180 bits (456), Expect = 3e-45
 Identities = 89/186 (47%), Positives = 123/186 (66%), Gaps = 1/186 (0%)
 Frame = +1

Query: 4   AGXNVTKVEQITHFPEMLDGRVKTLHPSIHGGILARRDQEHHLKALNEHGIGTFDVVVVN 183
           AG     ++ +T FPEM+DGRVKTLHP+IHGG+LARRD + HL+A NE+ I   D+VVVN
Sbjct: 42  AGVETIAIDDVTGFPEMMDGRVKTLHPNIHGGLLARRDLDSHLEAANENQIELIDLVVVN 101

Query: 184 LYPFYDKVTSGAISFEDGIENIDIGGPTLIRAAAKNHKDVLVVVDHRDYPALLKYLQEK- 360
           LYPF + +    +++ D +ENIDIGGP+++R+AAKNH  V VVVD  DY  +L  L    
Sbjct: 102 LYPFKETILKPDVTYADAVENIDIGGPSMLRSAAKNHASVTVVVDPADYTVVLDELSANG 161

Query: 361 QVDPQFRRMLAWKAFQHVASYDSAVSEWLWKQSNSGDIFPPSFTVPLSMKSTLRYGENPH 540
           +   + R+ LA K F+H A+YD+ ++E+   Q   G+  P   T+   +K  +RYGENP 
Sbjct: 162 ETTYETRQRLAAKVFRHTAAYDALIAEYFTAQ--VGESKPEKLTLTYDLKQAMRYGENPQ 219

Query: 541 QKAAFY 558
           Q A FY
Sbjct: 220 QDADFY 225

---

>PUR9_STRMU (Q8DWK8) Bifunctional purine biosynthesis protein purH [Includes:|
           Phosphoribosylaminoimidazolecarboxamide
           formyltransferase (EC 2.1.2.3) (AICAR transformylase);
           IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
           synthetase) (ATIC)]
          Length = 515

 Score =  179 bits (453), Expect = 7e-45
 Identities = 88/186 (47%), Positives = 122/186 (65%), Gaps = 1/186 (0%)
 Frame = +1

Query: 4   AGXNVTKVEQITHFPEMLDGRVKTLHPSIHGGILARRDQEHHLKALNEHGIGTFDVVVVN 183
           AG +   ++ +T FPEM+DGRVKTLHP+IHGG+LARRD + H+ A+ EH I   D+VVVN
Sbjct: 42  AGIDTIAIDDVTGFPEMMDGRVKTLHPNIHGGLLARRDLDSHVNAMKEHEITPIDLVVVN 101

Query: 184 LYPFYDKVTSGAISFEDGIENIDIGGPTLIRAAAKNHKDVLVVVDHRDYPALLKYLQEK- 360
           LYPF + +     ++ D +ENIDIGGP+++R+AAKNH  V VVVD  DY  +L  L    
Sbjct: 102 LYPFKETILKPDATYADAVENIDIGGPSMLRSAAKNHASVTVVVDPADYAEILDELSANG 161

Query: 361 QVDPQFRRMLAWKAFQHVASYDSAVSEWLWKQSNSGDIFPPSFTVPLSMKSTLRYGENPH 540
           +   + R+ LA K F+H A+YD+ ++E+   Q   G+  P   T+   +K  +RYGENP 
Sbjct: 162 ETSFETRKRLAAKVFRHTAAYDALIAEYFTAQ--VGEEKPEKLTLTYDLKQPMRYGENPQ 219

Query: 541 QKAAFY 558
           Q A FY
Sbjct: 220 QNADFY 225

---

>PUR9_STRA5 (P67546) Bifunctional purine biosynthesis protein purH [Includes:|
           Phosphoribosylaminoimidazolecarboxamide
           formyltransferase (EC 2.1.2.3) (AICAR transformylase);
           IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
           synthetase) (ATIC)]
          Length = 515

 Score =  178 bits (452), Expect = 9e-45
 Identities = 88/186 (47%), Positives = 124/186 (66%), Gaps = 1/186 (0%)
 Frame = +1

Query: 4   AGXNVTKVEQITHFPEMLDGRVKTLHPSIHGGILARRDQEHHLKALNEHGIGTFDVVVVN 183
           AG     ++ +T FPEM+DGRVKTLHP+IHGG+LARRD + HL+A  ++ I   D+VVVN
Sbjct: 42  AGVETIAIDDVTGFPEMMDGRVKTLHPNIHGGLLARRDADSHLQAAKDNNIELIDLVVVN 101

Query: 184 LYPFYDKVTSGAISFEDGIENIDIGGPTLIRAAAKNHKDVLVVVDHRDYPALLKYLQE-K 360
           LYPF + +    ++++  +ENIDIGGP+++R+AAKNH  V VVVD  DY  +L  L +  
Sbjct: 102 LYPFKETILRPDVTYDLAVENIDIGGPSMLRSAAKNHASVTVVVDSADYATVLGELADAS 161

Query: 361 QVDPQFRRMLAWKAFQHVASYDSAVSEWLWKQSNSGDIFPPSFTVPLSMKSTLRYGENPH 540
           Q   + R+ LA KAF+H A+YD+ ++E+   Q   G+  P   T+   +K  +RYGENP 
Sbjct: 162 QTTFKTRQRLAAKAFRHTAAYDALIAEYFTAQ--VGEAKPEKLTITYDLKQAMRYGENPQ 219

Query: 541 QKAAFY 558
           Q A FY
Sbjct: 220 QDADFY 225

---

>PUR9_STRA3 (P67545) Bifunctional purine biosynthesis protein purH [Includes:|
           Phosphoribosylaminoimidazolecarboxamide
           formyltransferase (EC 2.1.2.3) (AICAR transformylase);
           IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
           synthetase) (ATIC)]
          Length = 515

 Score =  178 bits (452), Expect = 9e-45
 Identities = 88/186 (47%), Positives = 124/186 (66%), Gaps = 1/186 (0%)
 Frame = +1

Query: 4   AGXNVTKVEQITHFPEMLDGRVKTLHPSIHGGILARRDQEHHLKALNEHGIGTFDVVVVN 183
           AG     ++ +T FPEM+DGRVKTLHP+IHGG+LARRD + HL+A  ++ I   D+VVVN
Sbjct: 42  AGVETIAIDDVTGFPEMMDGRVKTLHPNIHGGLLARRDADSHLQAAKDNNIELIDLVVVN 101

Query: 184 LYPFYDKVTSGAISFEDGIENIDIGGPTLIRAAAKNHKDVLVVVDHRDYPALLKYLQE-K 360
           LYPF + +    ++++  +ENIDIGGP+++R+AAKNH  V VVVD  DY  +L  L +  
Sbjct: 102 LYPFKETILRPDVTYDLAVENIDIGGPSMLRSAAKNHASVTVVVDSADYATVLGELADAS 161

Query: 361 QVDPQFRRMLAWKAFQHVASYDSAVSEWLWKQSNSGDIFPPSFTVPLSMKSTLRYGENPH 540
           Q   + R+ LA KAF+H A+YD+ ++E+   Q   G+  P   T+   +K  +RYGENP 
Sbjct: 162 QTTFKTRQRLAAKAFRHTAAYDALIAEYFTAQ--VGEAKPEKLTITYDLKQAMRYGENPQ 219

Query: 541 QKAAFY 558
           Q A FY
Sbjct: 220 QDADFY 225

---

>PUR9_STRP6 (Q5XEF2) Bifunctional purine biosynthesis protein purH [Includes:|
           Phosphoribosylaminoimidazolecarboxamide
           formyltransferase (EC 2.1.2.3) (AICAR transformylase);
           IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
           synthetase) (ATIC)]
          Length = 515

 Score =  177 bits (449), Expect = 2e-44
 Identities = 87/186 (46%), Positives = 124/186 (66%), Gaps = 1/186 (0%)
 Frame = +1

Query: 4   AGXNVTKVEQITHFPEMLDGRVKTLHPSIHGGILARRDQEHHLKALNEHGIGTFDVVVVN 183
           AG     ++ +T FPEM+DGRVKTLHP+IHGG+LARRD + HL+A  ++ I   D+VVVN
Sbjct: 42  AGVETIAIDDVTGFPEMMDGRVKTLHPNIHGGLLARRDVDSHLQAAKDNNIELIDLVVVN 101

Query: 184 LYPFYDKVTSGAISFEDGIENIDIGGPTLIRAAAKNHKDVLVVVDHRDYPALLKYLQEK- 360
           LYPF + +    ++++  +ENIDIGGP+++R+AAKNH  V VVVD  DY  +L  L +  
Sbjct: 102 LYPFKETILRPDVTYDLAVENIDIGGPSMLRSAAKNHASVTVVVDPADYATVLGELADAG 161

Query: 361 QVDPQFRRMLAWKAFQHVASYDSAVSEWLWKQSNSGDIFPPSFTVPLSMKSTLRYGENPH 540
           Q   + R+ LA K F+H+A+YD+ ++E+   Q   G+  P   T+   +K  +RYGENP 
Sbjct: 162 QTTFETRQRLAAKVFRHIAAYDALIAEYFTAQ--VGEAKPEKLTITYDLKQAMRYGENPQ 219

Query: 541 QKAAFY 558
           Q A FY
Sbjct: 220 QDADFY 225

---

>PUR9_NEIMA (Q9JUQ8) Bifunctional purine biosynthesis protein purH [Includes:|
           Phosphoribosylaminoimidazolecarboxamide
           formyltransferase (EC 2.1.2.3) (AICAR transformylase);
           IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
           synthetase) (ATIC)]
          Length = 530

 Score =  177 bits (448), Expect = 3e-44
 Identities = 96/198 (48%), Positives = 118/198 (59%), Gaps = 11/198 (5%)
 Frame = +1

Query: 4   AGXNVTKVEQITHFPEMLDGRVKTLHPSIHGGILARRDQEHHLKALNEHGIGTFDVVVVN 183
           AG  V +V   T FPEMLDGRVKTLHP IHGGIL RRD   H+  + EHGIG  D+V VN
Sbjct: 44  AGVPVIEVADYTGFPEMLDGRVKTLHPKIHGGILGRRDLPEHVAKMEEHGIGNIDLVCVN 103

Query: 184 LYPFYDKVTSGAISFEDGIENIDIGGPTLIRAAAKNHKDVLVVVDHRDYPALLKYLQEKQ 363
           LYPF   +     + ED IENIDIGGPT++R+AAKN K V +V D  D+PA+   ++   
Sbjct: 104 LYPFAATIAKPNCTLEDAIENIDIGGPTMVRSAAKNWKHVAIVTDPADFPAIAAEMEANN 163

Query: 364 --VDPQFRRMLAWKAFQHVASYDSAVSEWLWKQSNSGDI---------FPPSFTVPLSMK 510
             +  + R  L+ KAF H A YD  +S +L   S S D+         FP  F       
Sbjct: 164 GALSDKTRFNLSRKAFSHTAQYDGMISNYL--TSLSDDVLSGTPEIGEFPSQFNQSWIKV 221

Query: 511 STLRYGENPHQKAAFYGD 564
             +RYGENPHQ+AAFY D
Sbjct: 222 QDMRYGENPHQRAAFYRD 239

---

>PUR9_STRP3 (Q8K8Y6) Bifunctional purine biosynthesis protein purH [Includes:|
           Phosphoribosylaminoimidazolecarboxamide
           formyltransferase (EC 2.1.2.3) (AICAR transformylase);
           IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
           synthetase) (ATIC)]
          Length = 515

 Score =  177 bits (448), Expect = 3e-44
 Identities = 88/186 (47%), Positives = 123/186 (66%), Gaps = 1/186 (0%)
 Frame = +1

Query: 4   AGXNVTKVEQITHFPEMLDGRVKTLHPSIHGGILARRDQEHHLKALNEHGIGTFDVVVVN 183
           AG     ++ +T FPEM+DGRVKTLHP+IHGG+LARRD + HL+A  ++ I   D+VVVN
Sbjct: 42  AGVETIAIDDVTGFPEMMDGRVKTLHPNIHGGLLARRDADSHLQAAKDNNIELIDLVVVN 101

Query: 184 LYPFYDKVTSGAISFEDGIENIDIGGPTLIRAAAKNHKDVLVVVDHRDYPALLKYLQEK- 360
           LYPF + +    I+++  +ENIDIGGP+++R+AAKNH  V VVVD  DY  +L  L +  
Sbjct: 102 LYPFKETILRPDITYDLAVENIDIGGPSMLRSAAKNHASVTVVVDPADYATVLGELADAG 161

Query: 361 QVDPQFRRMLAWKAFQHVASYDSAVSEWLWKQSNSGDIFPPSFTVPLSMKSTLRYGENPH 540
           Q   + R+ LA K F+H A+YD+ ++E+   Q   G+  P   T+   +K  +RYGENP 
Sbjct: 162 QTTFETRQRLAAKVFRHTAAYDALIAEYFTTQ--VGEAKPEKLTITYDLKQAMRYGENPQ 219

Query: 541 QKAAFY 558
           Q A FY
Sbjct: 220 QDADFY 225

---

>PUR9_STRPN (Q97T99) Bifunctional purine biosynthesis protein purH [Includes:|
           Phosphoribosylaminoimidazolecarboxamide
           formyltransferase (EC 2.1.2.3) (AICAR transformylase);
           IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
           synthetase) (ATIC)]
          Length = 515

 Score =  176 bits (447), Expect = 3e-44
 Identities = 87/186 (46%), Positives = 123/186 (66%), Gaps = 1/186 (0%)
 Frame = +1

Query: 4   AGXNVTKVEQITHFPEMLDGRVKTLHPSIHGGILARRDQEHHLKALNEHGIGTFDVVVVN 183
           AG +   ++ +T FPEM+DGRVKTLHP+IHGG+LARRD + HL+A  ++ I   D+VVVN
Sbjct: 42  AGVDTIAIDDVTGFPEMMDGRVKTLHPNIHGGLLARRDLDSHLEAAKDNKIELIDLVVVN 101

Query: 184 LYPFYDKVTSGAISFEDGIENIDIGGPTLIRAAAKNHKDVLVVVDHRDYPALLKYLQEK- 360
           LYPF + +    +++ D +ENIDIGGP+++R+AAKNH  V VVVD  DY  +L  L    
Sbjct: 102 LYPFKETILKPDVTYADAVENIDIGGPSMLRSAAKNHASVTVVVDPADYAVVLDELAANG 161

Query: 361 QVDPQFRRMLAWKAFQHVASYDSAVSEWLWKQSNSGDIFPPSFTVPLSMKSTLRYGENPH 540
           +   + R+ LA K F+H A+YD+ ++E+   Q   G+  P   T+   +K  +RYGENP 
Sbjct: 162 ETSYETRQRLAAKVFRHTAAYDALIAEYFTAQ--VGESKPEKLTLTYDLKQPMRYGENPQ 219

Query: 541 QKAAFY 558
           Q A FY
Sbjct: 220 QDADFY 225

---

>PUR9_LACPL (Q88U29) Bifunctional purine biosynthesis protein purH [Includes:|
           Phosphoribosylaminoimidazolecarboxamide
           formyltransferase (EC 2.1.2.3) (AICAR transformylase);
           IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
           synthetase) (ATIC)]
          Length = 510

 Score =  176 bits (446), Expect = 4e-44
 Identities = 91/186 (48%), Positives = 117/186 (62%)
 Frame = +1

Query: 1   AAGXNVTKVEQITHFPEMLDGRVKTLHPSIHGGILARRDQEHHLKALNEHGIGTFDVVVV 180
           AA   V  +E++T FPEMLDGRVKTLHP +H G+LARRD   H+  L   GI   D+VVV
Sbjct: 41  AADIPVIGIEEVTGFPEMLDGRVKTLHPKVHAGLLARRDLPAHMAQLKAAGIQPIDMVVV 100

Query: 181 NLYPFYDKVTSGAISFEDGIENIDIGGPTLIRAAAKNHKDVLVVVDHRDYPALLKYLQEK 360
           NLYPF   +    ++  + IE IDIGGP+++R+AAKN   VL +VD  DY  +L  LQ  
Sbjct: 101 NLYPFKATIQQPDVTQAEAIEQIDIGGPSMLRSAAKNFAAVLPIVDPADYEQILADLQTD 160

Query: 361 QVDPQFRRMLAWKAFQHVASYDSAVSEWLWKQSNSGDIFPPSFTVPLSMKSTLRYGENPH 540
            V P  R+ LA K FQH A+YD+ ++++L  +      FP   T+    K  LRYGEN H
Sbjct: 161 AVTPALRQRLAAKVFQHTAAYDALIAQYLTTEE-----FPEKLTLTYDKKQALRYGENSH 215

Query: 541 QKAAFY 558
           QKAAFY
Sbjct: 216 QKAAFY 221

---

>PUR9_STRP8 (Q8P310) Bifunctional purine biosynthesis protein purH [Includes:|
           Phosphoribosylaminoimidazolecarboxamide
           formyltransferase (EC 2.1.2.3) (AICAR transformylase);
           IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
           synthetase) (ATIC)]
          Length = 515

 Score =  176 bits (445), Expect = 6e-44
 Identities = 86/186 (46%), Positives = 123/186 (66%), Gaps = 1/186 (0%)
 Frame = +1

Query: 4   AGXNVTKVEQITHFPEMLDGRVKTLHPSIHGGILARRDQEHHLKALNEHGIGTFDVVVVN 183
           AG     ++ +T FPEM+DGRVKTLHP+IHGG+LARRD + HL+A  ++ I   D+VV+N
Sbjct: 42  AGVETIAIDDVTGFPEMMDGRVKTLHPNIHGGLLARRDVDSHLQAAKDNNIELIDLVVIN 101

Query: 184 LYPFYDKVTSGAISFEDGIENIDIGGPTLIRAAAKNHKDVLVVVDHRDYPALLKYLQEK- 360
           LYPF + +    ++++  +ENIDIGGP+++R+AAKNH  V VVVD  DY  +L  L +  
Sbjct: 102 LYPFKETILRPDVTYDLAVENIDIGGPSMLRSAAKNHASVTVVVDPADYATVLGELADAG 161

Query: 361 QVDPQFRRMLAWKAFQHVASYDSAVSEWLWKQSNSGDIFPPSFTVPLSMKSTLRYGENPH 540
           Q   + R+ LA K F+H A+YD+ ++E+   Q   G+  P   T+   +K  +RYGENP 
Sbjct: 162 QTTFETRQRLAAKVFRHTAAYDALIAEYFTAQ--VGEAKPEKLTITYDLKQAMRYGENPQ 219

Query: 541 QKAAFY 558
           Q A FY
Sbjct: 220 QDADFY 225

---

>PUR9_YERPE (Q8ZAR3) Bifunctional purine biosynthesis protein purH [Includes:|
           Phosphoribosylaminoimidazolecarboxamide
           formyltransferase (EC 2.1.2.3) (AICAR transformylase);
           IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
           synthetase) (ATIC)]
          Length = 529

 Score =  175 bits (444), Expect = 7e-44
 Identities = 97/195 (49%), Positives = 121/195 (62%), Gaps = 10/195 (5%)
 Frame = +1

Query: 4   AGXNVTKVEQITHFPEMLDGRVKTLHPSIHGGILARRDQEHHLKALNEHGIGTFDVVVVN 183
           AG  VT+V   T FPEM+DGRVKTLHP +HGGIL RR Q+  + A  +HGI   D+VVVN
Sbjct: 47  AGLPVTEVSDYTGFPEMMDGRVKTLHPKVHGGILGRRGQDDGIMA--QHGIQPIDIVVVN 104

Query: 184 LYPFYDKVTSGAISFEDGIENIDIGGPTLIRAAAKNHKDVLVVVDHRDYPALLKYLQEKQ 363
           LYPF   V     S ED +ENIDIGGPT++R+AAKNHKDV +VV   DYPA++  L    
Sbjct: 105 LYPFAQTVARPDCSLEDAVENIDIGGPTMVRSAAKNHKDVAIVVKSSDYPAIITELDNND 164

Query: 364 VDPQF--RRMLAWKAFQHVASYDSAVSEWLWK--QSNSGDIFPPSFTVPLSM------KS 513
               +  R  LA KAF+H A+YDS ++ +         GD   PS   P ++      K 
Sbjct: 165 GSLTYPTRFNLAIKAFEHTAAYDSMIANYFGTLVPPYHGDTEQPSGHFPRTLNLNYIKKQ 224

Query: 514 TLRYGENPHQKAAFY 558
            +RYGEN HQ+AAFY
Sbjct: 225 DMRYGENSHQQAAFY 239

---

>PUR9_CLOPE (Q8XMK2) Bifunctional purine biosynthesis protein purH [Includes:|
           Phosphoribosylaminoimidazolecarboxamide
           formyltransferase (EC 2.1.2.3) (AICAR transformylase);
           IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
           synthetase) (ATIC)]
          Length = 501

 Score =  175 bits (444), Expect = 7e-44
 Identities = 91/182 (50%), Positives = 123/182 (67%), Gaps = 1/182 (0%)
 Frame = +1

Query: 16  VTKVEQITHFPEMLDGRVKTLHPSIHGGILARRDQEHHLKALNEHGIGTFDVVVVNLYPF 195
           V ++ +IT FPEMLDGRVKTLHP +H GILA RD + H+K L E  I T D VVVNLYPF
Sbjct: 46  VKEISEITDFPEMLDGRVKTLHPLVHAGILAIRDNKEHMKTLEEREINTIDYVVVNLYPF 105

Query: 196 YDKVTSGAISFEDGIENIDIGGPTLIRAAAKNHKDVLVVVDHRDYPALLKYLQEKQ-VDP 372
           ++KV    +SFE+ +E IDIGGPT++RAAAKN KDV+V+ D +DY  ++  ++E   V  
Sbjct: 106 FEKVRED-LSFEEKVEFIDIGGPTMLRAAAKNFKDVVVLSDKKDYEKVMNEIKENNCVSF 164

Query: 373 QFRRMLAWKAFQHVASYDSAVSEWLWKQSNSGDIFPPSFTVPLSMKSTLRYGENPHQKAA 552
           + R+ LA K F  +++YD+A+S +L +       +P   +V       LRYGENPHQ AA
Sbjct: 165 KLRKTLAGKVFNLMSAYDAAISNFLLEGEEE---YPEYLSVSYKKIQDLRYGENPHQGAA 221

Query: 553 FY 558
           +Y
Sbjct: 222 YY 223

---

>PUR9_CLOAB (Q97J91) Bifunctional purine biosynthesis protein purH [Includes:|
           Phosphoribosylaminoimidazolecarboxamide
           formyltransferase (EC 2.1.2.3) (AICAR transformylase);
           IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
           synthetase) (ATIC)]
          Length = 499

 Score =  175 bits (444), Expect = 7e-44
 Identities = 93/185 (50%), Positives = 123/185 (66%), Gaps = 1/185 (0%)
 Frame = +1

Query: 7   GXNVTKVEQITHFPEMLDGRVKTLHPSIHGGILARRDQEHHLKALNEHGIGTFDVVVVNL 186
           G  V +V ++T F E+LDGRVKTLHP IHGGILA RD + H+  +   GI   D+VVVNL
Sbjct: 43  GIPVIEVSEVTGFDEILDGRVKTLHPKIHGGILAIRDNKEHMDTIKNKGITPIDMVVVNL 102

Query: 187 YPFYDKVTSGAISFEDGIENIDIGGPTLIRAAAKNHKDVLVVVDHRDYPALLKYLQEK-Q 363
           YPF+DKV    ISFE+ +E IDIGGPT+IRAAAKN +DV+V+ D  DY  ++  +++  +
Sbjct: 103 YPFFDKVKEN-ISFEEKVEFIDIGGPTMIRAAAKNFQDVVVLTDVNDYDDVIDQIEKTGE 161

Query: 364 VDPQFRRMLAWKAFQHVASYDSAVSEWLWKQSNSGDIFPPSFTVPLSMKSTLRYGENPHQ 543
           V    ++ LA K F  +++YD A+S +L +     D +P    VP   K  LRYGENPHQ
Sbjct: 162 VAYNTKKRLAGKVFNLMSAYDGAISRFLLE-----DEYPEYLAVPYKKKMDLRYGENPHQ 216

Query: 544 KAAFY 558
            AAFY
Sbjct: 217 TAAFY 221

---

>PUR9_NEIMB (Q9JZM7) Bifunctional purine biosynthesis protein purH [Includes:|
           Phosphoribosylaminoimidazolecarboxamide
           formyltransferase (EC 2.1.2.3) (AICAR transformylase);
           IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
           synthetase) (ATIC)]
          Length = 526

 Score =  174 bits (441), Expect = 2e-43
 Identities = 96/198 (48%), Positives = 118/198 (59%), Gaps = 11/198 (5%)
 Frame = +1

Query: 4   AGXNVTKVEQITHFPEMLDGRVKTLHPSIHGGILARRDQEHHLKALNEHGIGTFDVVVVN 183
           AG  V +V   T FPEMLDGRVKTLHP IHGGIL RRD + H+  + EHGIG  D+V VN
Sbjct: 44  AGVPVIEVADYTGFPEMLDGRVKTLHPKIHGGILGRRDLDEHVAKMEEHGIGNIDLVCVN 103

Query: 184 LYPFYDKVTSGAISFEDGIENIDIGGPTLIRAAAKNHKDVLVVVDHRDYPALLKYLQEKQ 363
           LY F   +     + ED IENIDIGGPT++R+AAKN K V +V D  D+PA+   L+   
Sbjct: 104 LYLFAATIAKPNCTLEDAIENIDIGGPTMVRSAAKNWKHVAIVTDTADFPAIAAELEANN 163

Query: 364 --VDPQFRRMLAWKAFQHVASYDSAVSEWLWKQSNSGDI---------FPPSFTVPLSMK 510
             +  + R  L+ KAF H A YD  +S +L   S S D+         FP  F       
Sbjct: 164 GALSDKTRFNLSRKAFSHTAQYDGMISNYL--TSLSDDVLSGTPEIAGFPGRFNQSWIKV 221

Query: 511 STLRYGENPHQKAAFYGD 564
             +RYGENPHQ+AAFY D
Sbjct: 222 QDMRYGENPHQRAAFYRD 239

---

>PUR9_CLOTE (Q892X3) Bifunctional purine biosynthesis protein purH [Includes:|
           Phosphoribosylaminoimidazolecarboxamide
           formyltransferase (EC 2.1.2.3) (AICAR transformylase);
           IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
           synthetase) (ATIC)]
          Length = 499

 Score =  174 bits (441), Expect = 2e-43
 Identities = 89/182 (48%), Positives = 126/182 (69%), Gaps = 1/182 (0%)
 Frame = +1

Query: 16  VTKVEQITHFPEMLDGRVKTLHPSIHGGILARRDQEHHLKALNEHGIGTFDVVVVNLYPF 195
           V +V QIT+F E+LDGRVKTLHP++HGGILA RD + H+  + +  I   D+V+VNLYPF
Sbjct: 46  VKEVSQITNFDEILDGRVKTLHPAVHGGILAIRDNKEHMDTIKDKNIEPIDMVIVNLYPF 105

Query: 196 YDKVTSGAISFEDGIENIDIGGPTLIRAAAKNHKDVLVVVDHRDYPALLKYLQ-EKQVDP 372
           ++K+  G +S E+ IE IDIGGPT+IRAAAKN KDV+V+ D +DY  + + L+ E ++D 
Sbjct: 106 FEKIGKG-LSLEEQIEFIDIGGPTMIRAAAKNFKDVVVITDPKDYKRIEEKLEKEDEIDF 164

Query: 373 QFRRMLAWKAFQHVASYDSAVSEWLWKQSNSGDIFPPSFTVPLSMKSTLRYGENPHQKAA 552
             R+ LA K F  +++YD A+S++L ++      +P   ++       LRYGENPHQ AA
Sbjct: 165 NNRKTLAGKVFNLMSAYDGAISKFLLEEE-----YPEYLSLSYKKGKDLRYGENPHQTAA 219

Query: 553 FY 558
           FY
Sbjct: 220 FY 221

---

>PUR9_CAUCR (Q9ABY4) Bifunctional purine biosynthesis protein purH [Includes:|
           Phosphoribosylaminoimidazolecarboxamide
           formyltransferase (EC 2.1.2.3) (AICAR transformylase);
           IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
           synthetase) (ATIC)]
          Length = 529

 Score =  174 bits (440), Expect = 2e-43
 Identities = 90/186 (48%), Positives = 118/186 (63%)
 Frame = +1

Query: 1   AAGXNVTKVEQITHFPEMLDGRVKTLHPSIHGGILARRDQEHHLKALNEHGIGTFDVVVV 180
           AAG  V  V  +T FPEM+DGRVKTLHP +HGG+L  RD   H KA+ +HGIG  D++ V
Sbjct: 55  AAGVPVKDVSDLTGFPEMMDGRVKTLHPVVHGGLLGVRDAADHAKAMADHGIGGIDILYV 114

Query: 181 NLYPFYDKVTSGAISFEDGIENIDIGGPTLIRAAAKNHKDVLVVVDHRDYPALLKYLQEK 360
           NLYPF   V  G  S+ + +ENIDIGGP +IR+AAKNH  V V  D  D   +L+ L+  
Sbjct: 115 NLYPFEATVAKGG-SYAECVENIDIGGPAMIRSAAKNHGYVAVCTDPSDLAEVLEALKAG 173

Query: 361 QVDPQFRRMLAWKAFQHVASYDSAVSEWLWKQSNSGDIFPPSFTVPLSMKSTLRYGENPH 540
                 R+ LA +A+   A+YD+A+S W       G  FP   ++  +++ T+RYGENPH
Sbjct: 174 GTTLALRQQLAARAYARTAAYDAAISAWF--AEALGQDFPARKSIAGTLRQTMRYGENPH 231

Query: 541 QKAAFY 558
           QKAAFY
Sbjct: 232 QKAAFY 237

---

>PUR9_VIBF1 (Q5E257) Bifunctional purine biosynthesis protein purH [Includes:|
           Phosphoribosylaminoimidazolecarboxamide
           formyltransferase (EC 2.1.2.3) (AICAR transformylase);
           IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
           synthetase) (ATIC)]
          Length = 530

 Score =  173 bits (438), Expect = 4e-43
 Identities = 89/195 (45%), Positives = 120/195 (61%), Gaps = 11/195 (5%)
 Frame = +1

Query: 7   GXNVTKVEQITHFPEMLDGRVKTLHPSIHGGILARRDQEHHLKALNEHGIGTFDVVVVNL 186
           G +VT+V   T FPEM+DGRVKTLHP +HGG+L RR Q+  +  + +HGI   D+VVVNL
Sbjct: 48  GISVTEVSDYTGFPEMMDGRVKTLHPKVHGGVLGRRGQDDDI--MEQHGINPIDMVVVNL 105

Query: 187 YPFYDKVTSGAISFEDGIENIDIGGPTLIRAAAKNHKDVLVVVDHRDYPALLKYL--QEK 360
           YPF + V     +  D +ENIDIGGPT++R+AAKNHKDV +VV+  DY  ++  +   EK
Sbjct: 106 YPFAETVAKEGCTLADAVENIDIGGPTMVRSAAKNHKDVTIVVNAHDYDRVIAEMDANEK 165

Query: 361 QVDPQFRRMLAWKAFQHVASYDSAVSEWLW---------KQSNSGDIFPPSFTVPLSMKS 513
            +  + R  LA  AF+H ASYD  ++ +           K+ +    FP +F      K 
Sbjct: 166 SLTLETRFDLAIAAFEHTASYDGMIANYFGTMVPSYGENKEGDEESKFPRTFNQQFEKKQ 225

Query: 514 TLRYGENPHQKAAFY 558
            +RYGEN HQ AAFY
Sbjct: 226 DMRYGENSHQAAAFY 240

---

>PUR9_LACLA (Q9CFG0) Bifunctional purine biosynthesis protein purH [Includes:|
           Phosphoribosylaminoimidazolecarboxamide
           formyltransferase (EC 2.1.2.3) (AICAR transformylase);
           IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
           synthetase) (ATIC)]
          Length = 518

 Score =  172 bits (436), Expect = 6e-43
 Identities = 85/179 (47%), Positives = 120/179 (67%), Gaps = 1/179 (0%)
 Frame = +1

Query: 25  VEQITHFPEMLDGRVKTLHPSIHGGILARRDQEHHLKALNEHGIGTFDVVVVNLYPFYDK 204
           ++++T FPEM+DGR+KTLHP IHG +L RRD E H+K++ EH I   D+VVVNLYPF + 
Sbjct: 49  IDEVTGFPEMMDGRLKTLHPLIHGALLGRRDLESHMKSMTEHHISPIDLVVVNLYPFKET 108

Query: 205 VTSGAISFEDGIENIDIGGPTLIRAAAKNHKDVLVVVDHRDYPALLKYLQEK-QVDPQFR 381
           + +G  S  + IE IDIGGP+++R+AAKNH  V VV D  DY  +L  L  K +    FR
Sbjct: 109 LLAGG-SQAEMIEKIDIGGPSMLRSAAKNHASVTVVCDPNDYEKVLTELSVKGETSLSFR 167

Query: 382 RMLAWKAFQHVASYDSAVSEWLWKQSNSGDIFPPSFTVPLSMKSTLRYGENPHQKAAFY 558
           + LA K F+H ASYD+ ++++L ++    ++ P   T+   +K  +RYGENP Q A FY
Sbjct: 168 QQLAAKVFRHTASYDALIAQYLTEEFPVENVKPEKLTLTYDLKQGMRYGENPQQNADFY 226

---

>PUR9_SALTY (P26978) Bifunctional purine biosynthesis protein purH [Includes:|
           Phosphoribosylaminoimidazolecarboxamide
           formyltransferase (EC 2.1.2.3) (AICAR transformylase);
           IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
           synthetase) (ATIC)]
          Length = 529

 Score =  172 bits (435), Expect = 8e-43
 Identities = 91/194 (46%), Positives = 120/194 (61%), Gaps = 10/194 (5%)
 Frame = +1

Query: 7   GXNVTKVEQITHFPEMLDGRVKTLHPSIHGGILARRDQEHHLKALNEHGIGTFDVVVVNL 186
           G  VT+V   T FPEM+DGRVKTLHP +HGGIL RR Q+  +  + +H I   D+VVVNL
Sbjct: 48  GLPVTEVSDYTGFPEMMDGRVKTLHPKVHGGILGRRGQDDAI--MEQHHIAPIDMVVVNL 105

Query: 187 YPFYDKVTSGAISFEDGIENIDIGGPTLIRAAAKNHKDVLVVVDHRDYPALLKYL--QEK 360
           YPF + V     S ED +ENIDIGGPT++R+AAKNHKDV +VV   DY A++K +   E 
Sbjct: 106 YPFAETVAREGCSLEDAVENIDIGGPTMVRSAAKNHKDVAIVVKSSDYDAIIKEMDANEG 165

Query: 361 QVDPQFRRMLAWKAFQHVASYDSAVSEWL--------WKQSNSGDIFPPSFTVPLSMKST 516
            +    R  LA KAF+H A+YDS ++ +          +   +   FP +  +    K  
Sbjct: 166 SLTLDTRFDLAIKAFEHTAAYDSMIANYFGSMVPAYHGESKEAAGRFPRTLNLNFIKKQD 225

Query: 517 LRYGENPHQKAAFY 558
           +RYGEN HQ+AAFY
Sbjct: 226 MRYGENSHQQAAFY 239

---

>PUR9_RHOBA (Q7UKJ8) Bifunctional purine biosynthesis protein purH [Includes:|
           Phosphoribosylaminoimidazolecarboxamide
           formyltransferase (EC 2.1.2.3) (AICAR transformylase);
           IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
           synthetase) (ATIC)]
          Length = 523

 Score =  172 bits (435), Expect = 8e-43
 Identities = 92/190 (48%), Positives = 118/190 (62%), Gaps = 1/190 (0%)
 Frame = +1

Query: 4   AGXNVTKVEQITHFPEMLDGRVKTLHPSIHGGILARRDQEHHLKALNEHGIGTFDVVVVN 183
           +G  V  V + T FPEMLDGRVKTLHP I  GILARRD + H+  + +H I  FD+VVVN
Sbjct: 47  SGIKVEDVAEYTGFPEMLDGRVKTLHPRIFAGILARRDLDDHMDTIADHDIEPFDLVVVN 106

Query: 184 LYPFYDKVTSGAISFEDGIENIDIGGPTLIRAAAKNHKDVLVVVDHRDYPALLKYLQE-K 360
           LYPF   V+    +  + IE IDIGGP+L+RAAAKNH DV +      Y  +L  L+   
Sbjct: 107 LYPFAATVSRSGATRAECIEQIDIGGPSLVRAAAKNHGDVAIATSPEQYGDVLDQLETLG 166

Query: 361 QVDPQFRRMLAWKAFQHVASYDSAVSEWLWKQSNSGDIFPPSFTVPLSMKSTLRYGENPH 540
               + R  LA +AF H A YD A+++++   +  G+ FP S  V L  K+ LRYGENPH
Sbjct: 167 GTTDELRTQLAAEAFDHTAGYDRAIADYMQGDAVGGE-FPASMHVSLRRKTQLRYGENPH 225

Query: 541 QKAAFYGDRS 570
           Q+AA Y D S
Sbjct: 226 QRAALYSDSS 235

---

>PUR9_ECO57 (Q8X611) Bifunctional purine biosynthesis protein purH [Includes:|
           Phosphoribosylaminoimidazolecarboxamide
           formyltransferase (EC 2.1.2.3) (AICAR transformylase);
           IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
           synthetase) (ATIC)]
          Length = 529

 Score =  171 bits (434), Expect = 1e-42
 Identities = 91/194 (46%), Positives = 120/194 (61%), Gaps = 10/194 (5%)
 Frame = +1

Query: 7   GXNVTKVEQITHFPEMLDGRVKTLHPSIHGGILARRDQEHHLKALNEHGIGTFDVVVVNL 186
           G  VT+V   T FPEM+DGRVKTLHP +HGGIL RR Q+  +  + EH I   D+VVVNL
Sbjct: 48  GLPVTEVSDYTGFPEMMDGRVKTLHPKVHGGILGRRGQDDAI--MEEHQIQPIDMVVVNL 105

Query: 187 YPFYDKVTSGAISFEDGIENIDIGGPTLIRAAAKNHKDVLVVVDHRDYPALLKYLQEKQ- 363
           YPF   V     S ED +ENIDIGGPT++R+AAKNHKDV +VV   DY A++K + + + 
Sbjct: 106 YPFAQTVAREGCSLEDAVENIDIGGPTMVRSAAKNHKDVAIVVKSSDYDAIIKEMDDNEG 165

Query: 364 -VDPQFRRMLAWKAFQHVASYDSAVSEWL--------WKQSNSGDIFPPSFTVPLSMKST 516
            +    R  LA KAF+H A+YDS ++ +          +   +   FP +  +    K  
Sbjct: 166 SLTLATRFDLAIKAFEHTAAYDSMIANYFGSMVPAYHGESKEAAGRFPRTLNLNFIKKQD 225

Query: 517 LRYGENPHQKAAFY 558
           +RYGEN HQ+AAFY
Sbjct: 226 MRYGENSHQQAAFY 239

---

>PUR9_STRCO (Q9KY50) Bifunctional purine biosynthesis protein purH [Includes:|
           Phosphoribosylaminoimidazolecarboxamide
           formyltransferase (EC 2.1.2.3) (AICAR transformylase);
           IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
           synthetase) (ATIC)]
          Length = 523

 Score =  171 bits (434), Expect = 1e-42
 Identities = 96/190 (50%), Positives = 119/190 (62%), Gaps = 4/190 (2%)
 Frame = +1

Query: 1   AAGXNVTKVEQITHFPEMLDGRVKTLHPSIHGGILARRDQEHHLKALNEHGIGTFDVVVV 180
           AAG  VTKVE++T FPE LDGRVKTLHP +H GILA    E H + L+E G+  FD+VVV
Sbjct: 51  AAGVPVTKVEELTGFPECLDGRVKTLHPKVHAGILADLRLESHRQQLDELGVAPFDLVVV 110

Query: 181 NLYPFYDKVTSGAISFEDGIENIDIGGPTLIRAAAKNHKDVLVVVDHRDYPALLKYLQEK 360
           NLYPF + V SGA   ++ +E IDIGGP+++RAAAKNH  V VV     Y  +L  ++  
Sbjct: 111 NLYPFRETVASGATP-DECVEQIDIGGPSMVRAAAKNHPSVAVVTSPARYADVLLAVEGG 169

Query: 361 QVDPQFRRMLAWKAFQHVASYDSAVSEWLWKQ----SNSGDIFPPSFTVPLSMKSTLRYG 528
             D   R+ LA +AFQH A+YD AV+ W   +      SG  FP          +TLRYG
Sbjct: 170 GFDLAARKRLAAEAFQHTAAYDVAVASWFAAEYAPVDESG--FPDFLGATYERANTLRYG 227

Query: 529 ENPHQKAAFY 558
           ENPHQ AA Y
Sbjct: 228 ENPHQPAALY 237

---

>PUR9_ECOLI (P15639) Bifunctional purine biosynthesis protein purH [Includes:|
           Phosphoribosylaminoimidazolecarboxamide
           formyltransferase (EC 2.1.2.3) (AICAR transformylase);
           IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
           synthetase) (ATIC)]
          Length = 529

 Score =  171 bits (432), Expect = 2e-42
 Identities = 91/194 (46%), Positives = 120/194 (61%), Gaps = 10/194 (5%)
 Frame = +1

Query: 7   GXNVTKVEQITHFPEMLDGRVKTLHPSIHGGILARRDQEHHLKALNEHGIGTFDVVVVNL 186
           G  VT+V   T FPEM+DGRVKTLHP +HGGIL RR Q+  +  + EH I   D+VVVNL
Sbjct: 48  GLPVTEVSDYTGFPEMMDGRVKTLHPKVHGGILGRRGQDDAI--MEEHQIQPIDMVVVNL 105

Query: 187 YPFYDKVTSGAISFEDGIENIDIGGPTLIRAAAKNHKDVLVVVDHRDYPALLKYLQEKQ- 363
           YPF   V     S ED +ENIDIGGPT++R+AAKNHKDV +VV   DY A++K + + + 
Sbjct: 106 YPFAQTVAREGCSLEDAVENIDIGGPTMVRSAAKNHKDVAIVVKSSDYDAIIKEMDDNEG 165

Query: 364 -VDPQFRRMLAWKAFQHVASYDSAVSEWL--------WKQSNSGDIFPPSFTVPLSMKST 516
            +    R  LA KAF+H A+YDS ++ +          +   +   FP +  +    K  
Sbjct: 166 SLTLATRFDLAIKAFEHTAAYDSMIANYFGSMVPAYHGESKEAAGRFPRTLNLNFIKKLD 225

Query: 517 LRYGENPHQKAAFY 558
           +RYGEN HQ+AAFY
Sbjct: 226 MRYGENSHQQAAFY 239

---

>PUR9_LEPIN (Q8F3W6) Bifunctional purine biosynthesis protein purH [Includes:|
           Phosphoribosylaminoimidazolecarboxamide
           formyltransferase (EC 2.1.2.3) (AICAR transformylase);
           IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
           synthetase) (ATIC)]
          Length = 511

 Score =  170 bits (430), Expect = 3e-42
 Identities = 83/184 (45%), Positives = 110/184 (59%)
 Frame = +1

Query: 7   GXNVTKVEQITHFPEMLDGRVKTLHPSIHGGILARRDQEHHLKALNEHGIGTFDVVVVNL 186
           G     ++  T FPE+LDGRVKTLHP +HGG+L       H + + E  I   D+VVVNL
Sbjct: 45  GIAAIAIDDYTGFPEILDGRVKTLHPKVHGGLLGVISNPAHKQKMEELKIPKIDLVVVNL 104

Query: 187 YPFYDKVTSGAISFEDGIENIDIGGPTLIRAAAKNHKDVLVVVDHRDYPALLKYLQEKQV 366
           YPF   V+   +  E+ IENIDIGGP++IR+AAKN+K  LV+ D  DY  +   +    +
Sbjct: 105 YPFLKTVSKPEVQLEEAIENIDIGGPSMIRSAAKNYKHTLVLTDPNDYKKIQNLISSSGI 164

Query: 367 DPQFRRMLAWKAFQHVASYDSAVSEWLWKQSNSGDIFPPSFTVPLSMKSTLRYGENPHQK 546
             +       KAF H A YD+A+S W +KQ  SG++FP    +    K  LRYGENPHQ 
Sbjct: 165 SEEISASYMRKAFSHTAMYDAAISSWFYKQ--SGEVFPDVLNLSFIKKQKLRYGENPHQA 222

Query: 547 AAFY 558
           A+FY
Sbjct: 223 ASFY 226

---

>PUR9_LEPIC (Q72RT5) Bifunctional purine biosynthesis protein purH [Includes:|
           Phosphoribosylaminoimidazolecarboxamide
           formyltransferase (EC 2.1.2.3) (AICAR transformylase);
           IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
           synthetase) (ATIC)]
          Length = 511

 Score =  170 bits (430), Expect = 3e-42
 Identities = 83/184 (45%), Positives = 110/184 (59%)
 Frame = +1

Query: 7   GXNVTKVEQITHFPEMLDGRVKTLHPSIHGGILARRDQEHHLKALNEHGIGTFDVVVVNL 186
           G     ++  T FPE+LDGRVKTLHP +HGG+L       H + + E  I   D+VVVNL
Sbjct: 45  GIAAIAIDDYTGFPEILDGRVKTLHPKVHGGLLGVISNPAHKQKMEELKIPKIDLVVVNL 104

Query: 187 YPFYDKVTSGAISFEDGIENIDIGGPTLIRAAAKNHKDVLVVVDHRDYPALLKYLQEKQV 366
           YPF   V+   +  E+ IENIDIGGP++IR+AAKN+K  LV+ D  DY  +   +    +
Sbjct: 105 YPFLKTVSKPEVQLEEAIENIDIGGPSMIRSAAKNYKHTLVLTDPNDYKEIQNLISSSGI 164

Query: 367 DPQFRRMLAWKAFQHVASYDSAVSEWLWKQSNSGDIFPPSFTVPLSMKSTLRYGENPHQK 546
             +       KAF H A YD+A+S W +KQ  SG++FP    +    K  LRYGENPHQ 
Sbjct: 165 SEEISASYMRKAFSHTAMYDAAISSWFYKQ--SGEVFPDVLNLSFIKKQKLRYGENPHQA 222

Query: 547 AAFY 558
           A+FY
Sbjct: 223 ASFY 226

---

>PUR9_SALTI (Q8Z335) Bifunctional purine biosynthesis protein purH [Includes:|
           Phosphoribosylaminoimidazolecarboxamide
           formyltransferase (EC 2.1.2.3) (AICAR transformylase);
           IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
           synthetase) (ATIC)]
          Length = 529

 Score =  169 bits (429), Expect = 4e-42
 Identities = 90/194 (46%), Positives = 119/194 (61%), Gaps = 10/194 (5%)
 Frame = +1

Query: 7   GXNVTKVEQITHFPEMLDGRVKTLHPSIHGGILARRDQEHHLKALNEHGIGTFDVVVVNL 186
           G  VT+V   T FPEM+DGRVKTLHP +HGGIL RR Q+  +  + +H I   D+VVVNL
Sbjct: 48  GLPVTEVSDYTGFPEMMDGRVKTLHPKVHGGILGRRGQDDAI--MEQHHIAPIDMVVVNL 105

Query: 187 YPFYDKVTSGAISFEDGIENIDIGGPTLIRAAAKNHKDVLVVVDHRDYPALLKYL--QEK 360
           YPF + V     S  D +ENIDIGGPT++R+AAKNHKDV +VV   DY A++K +   E 
Sbjct: 106 YPFAETVAREGCSLADAVENIDIGGPTMVRSAAKNHKDVAIVVKSSDYDAIIKEMDANEG 165

Query: 361 QVDPQFRRMLAWKAFQHVASYDSAVSEWL--------WKQSNSGDIFPPSFTVPLSMKST 516
            +    R  LA KAF+H A+YDS ++ +          +   +   FP +  +    K  
Sbjct: 166 SLTLDTRFDLAIKAFEHTAAYDSMIANYFGSMVPAYHGESKEAAGRFPRTLNLNFIKKQD 225

Query: 517 LRYGENPHQKAAFY 558
           +RYGEN HQ+AAFY
Sbjct: 226 MRYGENSHQQAAFY 239

---

>PUR9_VIBPA (Q87KT0) Bifunctional purine biosynthesis protein purH [Includes:|
           Phosphoribosylaminoimidazolecarboxamide
           formyltransferase (EC 2.1.2.3) (AICAR transformylase);
           IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
           synthetase) (ATIC)]
          Length = 530

 Score =  169 bits (428), Expect = 5e-42
 Identities = 88/195 (45%), Positives = 119/195 (61%), Gaps = 11/195 (5%)
 Frame = +1

Query: 7   GXNVTKVEQITHFPEMLDGRVKTLHPSIHGGILARRDQEHHLKALNEHGIGTFDVVVVNL 186
           G  VT+V   T FPEM+DGRVKTLHP +HGG+L RR Q+  + A  +HGI   D+VVVNL
Sbjct: 48  GIAVTEVSDYTGFPEMMDGRVKTLHPKVHGGVLGRRGQDDDVMA--KHGINPIDMVVVNL 105

Query: 187 YPFYDKVTSGAISFEDGIENIDIGGPTLIRAAAKNHKDVLVVVDHRDYPALLKYL--QEK 360
           YPF + V     +  D +ENIDIGGPT++R+AAKNHKDV +VV+  DY  ++  +   +K
Sbjct: 106 YPFAETVAKDGCTLADAVENIDIGGPTMVRSAAKNHKDVTIVVNASDYDRVIAEMDANDK 165

Query: 361 QVDPQFRRMLAWKAFQHVASYDSAVSEWLW---------KQSNSGDIFPPSFTVPLSMKS 513
            +  + R  LA  AF+H A+YD  ++ +           K+ +    FP +F      K 
Sbjct: 166 SLTLETRFDLAIAAFEHTAAYDGMIANYFGTMVPSYGENKEGDEESKFPRTFNQQFEKKQ 225

Query: 514 TLRYGENPHQKAAFY 558
            +RYGEN HQ AAFY
Sbjct: 226 DMRYGENSHQAAAFY 240

---

>PUR9_BRUSU (P67540) Bifunctional purine biosynthesis protein purH [Includes:|
           Phosphoribosylaminoimidazolecarboxamide
           formyltransferase (EC 2.1.2.3) (AICAR transformylase);
           IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
           synthetase) (ATIC)]
          Length = 538

 Score =  169 bits (427), Expect = 7e-42
 Identities = 90/189 (47%), Positives = 122/189 (64%), Gaps = 3/189 (1%)
 Frame = +1

Query: 1   AAGXNVTKVEQITHFPEMLDGRVKTLHPSIHGGILARRDQEHHLKALNEHGIGTFDVVVV 180
           AAG  V  V +IT FPE++DGRVKTLHP++HGG+LA R+   H+ A+ EHGIG  D+ V+
Sbjct: 55  AAGIPVKDVSEITGFPEIMDGRVKTLHPAVHGGLLAVRNDPEHVAAMEEHGIGGIDLAVI 114

Query: 181 NLYPFYDKVTSGAISFEDGIENIDIGGPTLIRAAAKNHKDVLVVVDHRDYPALLKYLQEK 360
           NLYPF +    G   ++  +ENIDIGGP +IRA+AKNH  V  VVD  DY  ++  L++ 
Sbjct: 115 NLYPFEEVRFKGG-DYDTTVENIDIGGPAMIRASAKNHAYVATVVDPADYADVVAELEKH 173

Query: 361 --QVDPQFRRMLAWKAFQHVASYDSAVSEWLWKQSNSGDIFPPSF-TVPLSMKSTLRYGE 531
              +   FR+ LA KAF   A+YD+A+S W    + + D   P++  V   + S +RYGE
Sbjct: 174 SGSLPLAFRKKLAAKAFSRTAAYDAAISNWF---AEAIDEETPTYRAVAGKLHSVMRYGE 230

Query: 532 NPHQKAAFY 558
           NPHQ A FY
Sbjct: 231 NPHQTAGFY 239

---

>PUR9_BRUME (P67539) Bifunctional purine biosynthesis protein purH [Includes:|
           Phosphoribosylaminoimidazolecarboxamide
           formyltransferase (EC 2.1.2.3) (AICAR transformylase);
           IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
           synthetase) (ATIC)]
          Length = 538

 Score =  169 bits (427), Expect = 7e-42
 Identities = 90/189 (47%), Positives = 122/189 (64%), Gaps = 3/189 (1%)
 Frame = +1

Query: 1   AAGXNVTKVEQITHFPEMLDGRVKTLHPSIHGGILARRDQEHHLKALNEHGIGTFDVVVV 180
           AAG  V  V +IT FPE++DGRVKTLHP++HGG+LA R+   H+ A+ EHGIG  D+ V+
Sbjct: 55  AAGIPVKDVSEITGFPEIMDGRVKTLHPAVHGGLLAVRNDPEHVAAMEEHGIGGIDLAVI 114

Query: 181 NLYPFYDKVTSGAISFEDGIENIDIGGPTLIRAAAKNHKDVLVVVDHRDYPALLKYLQEK 360
           NLYPF +    G   ++  +ENIDIGGP +IRA+AKNH  V  VVD  DY  ++  L++ 
Sbjct: 115 NLYPFEEVRFKGG-DYDTTVENIDIGGPAMIRASAKNHAYVATVVDPADYADVVAELEKH 173

Query: 361 --QVDPQFRRMLAWKAFQHVASYDSAVSEWLWKQSNSGDIFPPSF-TVPLSMKSTLRYGE 531
              +   FR+ LA KAF   A+YD+A+S W    + + D   P++  V   + S +RYGE
Sbjct: 174 SGSLPLAFRKKLAAKAFSRTAAYDAAISNWF---AEAIDEETPTYRAVAGKLHSVMRYGE 230

Query: 532 NPHQKAAFY 558
           NPHQ A FY
Sbjct: 231 NPHQTAGFY 239

---

>PUR9_MYCTU (P67541) Bifunctional purine biosynthesis protein purH [Includes:|
           Phosphoribosylaminoimidazolecarboxamide
           formyltransferase (EC 2.1.2.3) (AICAR transformylase);
           IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
           synthetase) (ATIC)]
          Length = 523

 Score =  169 bits (427), Expect = 7e-42
 Identities = 94/189 (49%), Positives = 116/189 (61%), Gaps = 3/189 (1%)
 Frame = +1

Query: 7   GXNVTKVEQITHFPEMLDGRVKTLHPSIHGGILARRDQEHHLKALNEHGIGTFDVVVVNL 186
           G  VT VEQ+T FPE+LDGRVKTLHP +H G+LA   +  H  AL + GI  F++VVVNL
Sbjct: 51  GIPVTPVEQLTGFPEVLDGRVKTLHPRVHAGLLADLRKSEHAAALEQLGIEAFELVVVNL 110

Query: 187 YPFYDKVTSGAISFEDGIENIDIGGPTLIRAAAKNHKDVLVVVDHRDYPALLKYLQEKQV 366
           YPF   V SGA S +D +E IDIGGP ++RAAAKNH    VV D   Y  +L  L+    
Sbjct: 111 YPFSQTVESGA-SVDDCVEQIDIGGPAMVRAAAKNHPSAAVVTDPLGYHGVLAALRAGGF 169

Query: 367 DPQFRRMLAWKAFQHVASYDSAVSEWLWK---QSNSGDIFPPSFTVPLSMKSTLRYGENP 537
               R+ LA  AFQH+A YD AV+ W+ +     +    FP  F       + LRYGENP
Sbjct: 170 TLAERKRLASLAFQHIAEYDIAVASWMQQTLAPEHPVAAFPQWFGRSWRRVAMLRYGENP 229

Query: 538 HQKAAFYGD 564
           HQ+AA YGD
Sbjct: 230 HQQAALYGD 238

---

>PUR9_MYCBO (P67542) Bifunctional purine biosynthesis protein purH [Includes:|
           Phosphoribosylaminoimidazolecarboxamide
           formyltransferase (EC 2.1.2.3) (AICAR transformylase);
           IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
           synthetase) (ATIC)]
          Length = 523

 Score =  169 bits (427), Expect = 7e-42
 Identities = 94/189 (49%), Positives = 116/189 (61%), Gaps = 3/189 (1%)
 Frame = +1

Query: 7   GXNVTKVEQITHFPEMLDGRVKTLHPSIHGGILARRDQEHHLKALNEHGIGTFDVVVVNL 186
           G  VT VEQ+T FPE+LDGRVKTLHP +H G+LA   +  H  AL + GI  F++VVVNL
Sbjct: 51  GIPVTPVEQLTGFPEVLDGRVKTLHPRVHAGLLADLRKSEHAAALEQLGIEAFELVVVNL 110

Query: 187 YPFYDKVTSGAISFEDGIENIDIGGPTLIRAAAKNHKDVLVVVDHRDYPALLKYLQEKQV 366
           YPF   V SGA S +D +E IDIGGP ++RAAAKNH    VV D   Y  +L  L+    
Sbjct: 111 YPFSQTVESGA-SVDDCVEQIDIGGPAMVRAAAKNHPSAAVVTDPLGYHGVLAALRAGGF 169

Query: 367 DPQFRRMLAWKAFQHVASYDSAVSEWLWK---QSNSGDIFPPSFTVPLSMKSTLRYGENP 537
               R+ LA  AFQH+A YD AV+ W+ +     +    FP  F       + LRYGENP
Sbjct: 170 TLAERKRLASLAFQHIAEYDIAVASWMQQTLAPEHPVAAFPQWFGRSWRRVAMLRYGENP 229

Query: 538 HQKAAFYGD 564
           HQ+AA YGD
Sbjct: 230 HQQAALYGD 238

---

>PUR9_FUSNN (Q8REV6) Bifunctional purine biosynthesis protein purH [Includes:|
           Phosphoribosylaminoimidazolecarboxamide
           formyltransferase (EC 2.1.2.3) (AICAR transformylase);
           IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
           synthetase) (ATIC)]
          Length = 504

 Score =  169 bits (427), Expect = 7e-42
 Identities = 88/184 (47%), Positives = 124/184 (67%), Gaps = 1/184 (0%)
 Frame = +1

Query: 16  VTKVEQITHFPEMLDGRVKTLHPSIHGGILARRDQEHHLKALNEHGIGTFDVVVVNLYPF 195
           V +V +IT+F EMLDGRVKTLHP+IHGGILA RD E H++ L E  I T D V+VNLYPF
Sbjct: 46  VIEVSKITNFEEMLDGRVKTLHPNIHGGILALRDNEEHMRTLKERNIDTIDYVIVNLYPF 105

Query: 196 YDKVTSGAISFEDGIENIDIGGPTLIRAAAKNHKDVLVVVDHRDYPALLKYLQEK-QVDP 372
           ++KV    +SFE+ IE IDIGGPT++R+AAK+ K+V+V+ D +DY ++ + + +   V  
Sbjct: 106 FEKVKED-LSFEEKIEFIDIGGPTMLRSAAKSFKNVVVISDVKDYESIKEEINKSDDVSY 164

Query: 373 QFRRMLAWKAFQHVASYDSAVSEWLWKQSNSGDIFPPSFTVPLSMKSTLRYGENPHQKAA 552
           + R+ LA K F   ++YD+A+S++L  +      F     +       +RYGEN HQKAA
Sbjct: 165 EARKKLAGKVFNLTSAYDAAISQFLLDED-----FSEYLNISYKKFMEMRYGENSHQKAA 219

Query: 553 FYGD 564
           +Y D
Sbjct: 220 YYTD 223

---

>PUR9_STAES (Q8CT27) Bifunctional purine biosynthesis protein purH [Includes:|
           Phosphoribosylaminoimidazolecarboxamide
           formyltransferase (EC 2.1.2.3) (AICAR transformylase);
           IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
           synthetase) (ATIC)]
          Length = 492

 Score =  168 bits (426), Expect = 9e-42
 Identities = 85/184 (46%), Positives = 111/184 (60%)
 Frame = +1

Query: 4   AGXNVTKVEQITHFPEMLDGRVKTLHPSIHGGILARRDQEHHLKALNEHGIGTFDVVVVN 183
           A  N+  V ++T FPE++DGRVKTLHP++HGGILA RD+EHHL+ L E  I   D+VVVN
Sbjct: 41  ANINIKSVSELTQFPEIMDGRVKTLHPAVHGGILADRDKEHHLEQLREQHIDLIDMVVVN 100

Query: 184 LYPFYDKVTSGAISFEDGIENIDIGGPTLIRAAAKNHKDVLVVVDHRDYPALLKYLQEKQ 363
           LYPF   V    ++  D +ENIDIGGPT++RAAAKN K V  +V   DY  +++ ++  Q
Sbjct: 101 LYPFQQTVAQPDVTETDAVENIDIGGPTMLRAAAKNFKHVTTIVHPSDYNEVIERIKNHQ 160

Query: 364 VDPQFRRMLAWKAFQHVASYDSAVSEWLWKQSNSGDIFPPSFTVPLSMKSTLRYGENPHQ 543
           +D  +R+ L  K FQH   YD A+  +                     K TLRYGENP Q
Sbjct: 161 LDEAYRKSLMVKVFQHTNEYDHAIVNYF-----------------KDNKETLRYGENPQQ 203

Query: 544 KAAF 555
            A F
Sbjct: 204 SAYF 207

---

>PUR9_STAEQ (Q5HQ97) Bifunctional purine biosynthesis protein purH [Includes:|
           Phosphoribosylaminoimidazolecarboxamide
           formyltransferase (EC 2.1.2.3) (AICAR transformylase);
           IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
           synthetase) (ATIC)]
          Length = 492

 Score =  168 bits (426), Expect = 9e-42
 Identities = 85/184 (46%), Positives = 111/184 (60%)
 Frame = +1

Query: 4   AGXNVTKVEQITHFPEMLDGRVKTLHPSIHGGILARRDQEHHLKALNEHGIGTFDVVVVN 183
           A  N+  V ++T FPE++DGRVKTLHP++HGGILA RD+EHHL+ L E  I   D+VVVN
Sbjct: 41  ANINIKSVSELTQFPEIMDGRVKTLHPAVHGGILADRDKEHHLEQLREQHIDLIDMVVVN 100

Query: 184 LYPFYDKVTSGAISFEDGIENIDIGGPTLIRAAAKNHKDVLVVVDHRDYPALLKYLQEKQ 363
           LYPF   V    ++  D +ENIDIGGPT++RAAAKN K V  +V   DY  +++ ++  Q
Sbjct: 101 LYPFQQTVAQPDVTETDAVENIDIGGPTMLRAAAKNFKHVTTIVHPSDYNEVIERIKNHQ 160

Query: 364 VDPQFRRMLAWKAFQHVASYDSAVSEWLWKQSNSGDIFPPSFTVPLSMKSTLRYGENPHQ 543
           +D  +R+ L  K FQH   YD A+  +                     K TLRYGENP Q
Sbjct: 161 LDEAYRKSLMVKVFQHTNEYDHAIVNYF-----------------KDNKETLRYGENPQQ 203

Query: 544 KAAF 555
            A F
Sbjct: 204 SAYF 207

---

>PUR9_ECOL6 (Q8FB68) Bifunctional purine biosynthesis protein purH [Includes:|
           Phosphoribosylaminoimidazolecarboxamide
           formyltransferase (EC 2.1.2.3) (AICAR transformylase);
           IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
           synthetase) (ATIC)]
          Length = 529

 Score =  167 bits (424), Expect = 2e-41
 Identities = 91/194 (46%), Positives = 118/194 (60%), Gaps = 10/194 (5%)
 Frame = +1

Query: 7   GXNVTKVEQITHFPEMLDGRVKTLHPSIHGGILARRDQEHHLKALNEHGIGTFDVVVVNL 186
           G  VT+V   T FPEM+DGRVKTLHP +HGGIL RR  +  +  + EH I   D+VVVNL
Sbjct: 48  GLPVTEVSDYTGFPEMMDGRVKTLHPKVHGGILGRRGLDDAI--MEEHQILPIDMVVVNL 105

Query: 187 YPFYDKVTSGAISFEDGIENIDIGGPTLIRAAAKNHKDVLVVVDHRDYPALLKYL--QEK 360
           YPF   V     S ED +ENIDIGGPT++R+AAKNHKDV +VV   DY A++K +   E 
Sbjct: 106 YPFAQTVAREGCSLEDAVENIDIGGPTMVRSAAKNHKDVAIVVKSSDYDAIIKEMDANEG 165

Query: 361 QVDPQFRRMLAWKAFQHVASYDSAVSEWL--------WKQSNSGDIFPPSFTVPLSMKST 516
            +    R  LA KAF+H A+YDS ++ +          +   +   FP +  +    K  
Sbjct: 166 SLTLATRFDLAIKAFEHTAAYDSMIANYFGSMVPAYHGESKEAAGRFPRTLNLNFIKKQD 225

Query: 517 LRYGENPHQKAAFY 558
           +RYGEN HQ+AAFY
Sbjct: 226 MRYGENSHQQAAFY 239

---

>PUR9_AGRT5 (Q8UBM8) Bifunctional purine biosynthesis protein purH [Includes:|
           Phosphoribosylaminoimidazolecarboxamide
           formyltransferase (EC 2.1.2.3) (AICAR transformylase);
           IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
           synthetase) (ATIC)]
          Length = 538

 Score =  167 bits (424), Expect = 2e-41
 Identities = 88/188 (46%), Positives = 121/188 (64%), Gaps = 3/188 (1%)
 Frame = +1

Query: 4   AGXNVTKVEQITHFPEMLDGRVKTLHPSIHGGILARRDQEHHLKALNEHGIGTFDVVVVN 183
           AG  VT V  +T+FPE++DGRVKTLHP++HGG+LA RD   H++A+  HGI   D+ V+N
Sbjct: 56  AGLAVTDVSDVTNFPEIMDGRVKTLHPNVHGGLLAIRDDAEHVEAMKAHGIEAIDLSVIN 115

Query: 184 LYPFYDKVTSGAISFEDGIENIDIGGPTLIRAAAKNHKDVLVVVDHRDYPALLKYLQ--E 357
           LYPF ++V +    +   +ENIDIGGP +IRA+AKNH  V VV D  DYPAL++ LQ  +
Sbjct: 116 LYPF-EEVRAKGGDYPTTVENIDIGGPAMIRASAKNHAYVTVVTDPSDYPALVEALQADD 174

Query: 358 KQVDPQFRRMLAWKAFQHVASYDSAVSEWLWKQSNSGDIFPPSF-TVPLSMKSTLRYGEN 534
            Q     R+  A KA+   A+YD+ +S W    + +  I  P +  +   +K  +RYGEN
Sbjct: 175 GQTSYALRQRFAAKAYARTAAYDAVISNWF---AEALAIETPHYRAIGGVLKEKMRYGEN 231

Query: 535 PHQKAAFY 558
           PHQ A FY
Sbjct: 232 PHQSAGFY 239

---

>PUR9_DEIRA (Q9RW01) Bifunctional purine biosynthesis protein purH [Includes:|
           Phosphoribosylaminoimidazolecarboxamide
           formyltransferase (EC 2.1.2.3) (AICAR transformylase);
           IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
           synthetase) (ATIC)]
          Length = 510

 Score =  167 bits (424), Expect = 2e-41
 Identities = 95/186 (51%), Positives = 121/186 (65%), Gaps = 1/186 (0%)
 Frame = +1

Query: 4   AGXNVTKVEQITHFPEMLDGRVKTLHPSIHGGILARRDQEHHLKALNEHGIGTFDVVVVN 183
           AG  V +V  +T FPEMLDGRVKTLHP+IHGGILARR +  HL  L    IGT D+V VN
Sbjct: 42  AGIPVRQVSDVTGFPEMLDGRVKTLHPAIHGGILARR-EAGHLGQLAAQDIGTIDLVCVN 100

Query: 184 LYPFYDKVTSGAISFEDGIENIDIGGPTLIRAAAKNHKDVLVVVDHRDYPALLKYLQEKQ 363
           LYPF + V  GA    + IENIDIGGP +IR+AAKNH  VLV+VD  DY   L    + +
Sbjct: 101 LYPFRETVARGAPD-PEVIENIDIGGPAMIRSAAKNHDAVLVLVDPADYALAL----QDE 155

Query: 364 VDPQFRRMLAWKAFQHVASYDSAVSEWLWKQSNS-GDIFPPSFTVPLSMKSTLRYGENPH 540
           V P  RR LA KA++H + YD+A++ +L  +S+      P   ++ L+  + +RYGENPH
Sbjct: 156 VSPAERRRLAAKAYRHTSEYDAAITAYLSGESDELPTQLPEHLSLDLTRTAQVRYGENPH 215

Query: 541 QKAAFY 558
           Q  A Y
Sbjct: 216 QPGAIY 221

---

>PUR9_SYNEL (Q8DIN5) Bifunctional purine biosynthesis protein purH [Includes:|
           Phosphoribosylaminoimidazolecarboxamide
           formyltransferase (EC 2.1.2.3) (AICAR transformylase);
           IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
           synthetase) (ATIC)]
          Length = 518

 Score =  167 bits (424), Expect = 2e-41
 Identities = 95/192 (49%), Positives = 118/192 (61%), Gaps = 7/192 (3%)
 Frame = +1

Query: 4   AGXNVTKVEQITHFPEMLDGRVKTLHPSIHGGILARRDQEHHLKALNEHGIGTFDVVVVN 183
           AG  VT V + T  PE+L GRVKTLHP IHGGILARRD+      L    I   D+VVVN
Sbjct: 43  AGIPVTTVSEYTGAPEILGGRVKTLHPKIHGGILARRDRPQDEADLQAQAIHPIDLVVVN 102

Query: 184 LYPFYDKVTSGAISFEDGIENIDIGGPTLIRAAAKNHKDVLVVVDHRDYPALLKYLQEKQ 363
           LYPF + +    ++  + IE IDIGGPTLIRAAAKNH  V V+VD   Y     YLQE +
Sbjct: 103 LYPFAETIAQPNVTLAEAIEQIDIGGPTLIRAAAKNHAHVTVLVDPSQYET---YLQELR 159

Query: 364 V----DPQFRRMLAWKAFQHVASYDSAVSEWLWKQSNSG---DIFPPSFTVPLSMKSTLR 522
           +     P FR   A +AF   A YD A++E+L K + +G   +I PP F +    K  LR
Sbjct: 160 LYGDAQPAFRLACAQQAFALTAHYDQAIAEYLQKVTAAGTEPEILPPVFHLTGRQKQVLR 219

Query: 523 YGENPHQKAAFY 558
           YGENPHQ+A++Y
Sbjct: 220 YGENPHQRASWY 231

---

>PUR9_AQUAE (O67775) Bifunctional purine biosynthesis protein purH [Includes:|
           Phosphoribosylaminoimidazolecarboxamide
           formyltransferase (EC 2.1.2.3) (AICAR transformylase);
           IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
           synthetase) (ATIC)]
          Length = 506

 Score =  167 bits (424), Expect = 2e-41
 Identities = 91/184 (49%), Positives = 121/184 (65%)
 Frame = +1

Query: 7   GXNVTKVEQITHFPEMLDGRVKTLHPSIHGGILARRDQEHHLKALNEHGIGTFDVVVVNL 186
           G +V +V +IT FPE+L+GRVKTLHP +HGGIL R   E   + + +HGI   DVVVVNL
Sbjct: 41  GISVKEVSEITGFPEILEGRVKTLHPVVHGGILFRDWVEKDKEEIEKHGIKPIDVVVVNL 100

Query: 187 YPFYDKVTSGAISFEDGIENIDIGGPTLIRAAAKNHKDVLVVVDHRDYPALLKYLQEKQV 366
           YPF +K+  G ++ +D +E IDIGGPTLIRAAAKN   V+++VD  DY  +++ L++  +
Sbjct: 101 YPFEEKLKEG-LTDKDLMEFIDIGGPTLIRAAAKNFFRVVILVDPEDYDWVIEKLKKGNL 159

Query: 367 DPQFRRMLAWKAFQHVASYDSAVSEWLWKQSNSGDIFPPSFTVPLSMKSTLRYGENPHQK 546
             Q R  LAWKAF H A YD  +S+  +K+  S D F     +PL     LRYGENPHQ+
Sbjct: 160 TLQDRAYLAWKAFSHTAYYDGVISQ-AFKKLYSIDTFGKEEALPLKRMQKLRYGENPHQR 218

Query: 547 AAFY 558
              Y
Sbjct: 219 GFLY 222

---

>PUR9_COREF (Q8FR29) Bifunctional purine biosynthesis protein purH [Includes:|
           Phosphoribosylaminoimidazolecarboxamide
           formyltransferase (EC 2.1.2.3) (AICAR transformylase);
           IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
           synthetase) (ATIC)]
          Length = 521

 Score =  167 bits (423), Expect = 2e-41
 Identities = 89/187 (47%), Positives = 118/187 (63%), Gaps = 3/187 (1%)
 Frame = +1

Query: 7   GXNVTKVEQITHFPEMLDGRVKTLHPSIHGGILARRDQEHHLKALNEHGIGTFDVVVVNL 186
           G  VT VE++T FPE L+GRVKTLHP +H GILA   ++ HL+ L+E G+  F +VVVNL
Sbjct: 49  GIPVTPVEELTGFPECLEGRVKTLHPKVHAGILADTRKDDHLRQLDELGVTPFQLVVVNL 108

Query: 187 YPFYDKVTSGAISFEDGIENIDIGGPTLIRAAAKNHKDVLVVVDHRDYPALLKYLQEKQV 366
           YPF + V SGA  F+D +E IDIGGP+++RAAAKNH  V VV     Y  ++  L     
Sbjct: 109 YPFAETVASGA-DFDDCVEQIDIGGPSMVRAAAKNHPSVAVVTSPGQYEDVVSVLNTGGF 167

Query: 367 DPQFRRMLAWKAFQHVASYDSAVSEWLWKQSNSGDI---FPPSFTVPLSMKSTLRYGENP 537
               R  LA +AF+H A+YD  V+ W+ +Q ++ D    FP       ++  +LRYGENP
Sbjct: 168 SRAERTKLAAEAFRHTATYDVTVATWISEQLSAADTELEFPGWIGSTSTLARSLRYGENP 227

Query: 538 HQKAAFY 558
           HQ AA Y
Sbjct: 228 HQSAALY 234

---

>PUR9_VIBCH (Q9KV80) Bifunctional purine biosynthesis protein purH [Includes:|
           Phosphoribosylaminoimidazolecarboxamide
           formyltransferase (EC 2.1.2.3) (AICAR transformylase);
           IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
           synthetase) (ATIC)]
          Length = 530

 Score =  166 bits (421), Expect = 3e-41
 Identities = 88/195 (45%), Positives = 117/195 (60%), Gaps = 11/195 (5%)
 Frame = +1

Query: 7   GXNVTKVEQITHFPEMLDGRVKTLHPSIHGGILARRDQEHHLKALNEHGIGTFDVVVVNL 186
           G  VT+V   T FPEM+DGRVKTLHP +HGGIL RR Q+  +  +N HGI   D+VVVNL
Sbjct: 48  GLTVTEVSDYTGFPEMMDGRVKTLHPKVHGGILGRRGQDDAV--MNTHGIQPIDMVVVNL 105

Query: 187 YPFYDKVTSGAISFEDGIENIDIGGPTLIRAAAKNHKDVLVVVDHRDYPALLKYL--QEK 360
           YPF   V +   +  D +ENIDIGGPT++R+AAKNHKDV +VV+  DY  +++ +     
Sbjct: 106 YPFAQTVANPNCTLADAVENIDIGGPTMVRSAAKNHKDVAIVVNAHDYDRVIREMDANHN 165

Query: 361 QVDPQFRRMLAWKAFQHVASYDSAVSEWLW---------KQSNSGDIFPPSFTVPLSMKS 513
            +    R  LA  AF+H A+YD  ++ +           K+ +    FP +F      K 
Sbjct: 166 SLTLATRFDLAIAAFEHTAAYDGMIANYFGTLVPSYGDNKEGDEESKFPRTFNAQFIKKQ 225

Query: 514 TLRYGENPHQKAAFY 558
            +RYGEN HQ AAFY
Sbjct: 226 DMRYGENSHQAAAFY 240

---

>PUR9_STAAW (Q8NX88) Bifunctional purine biosynthesis protein purH [Includes:|
           Phosphoribosylaminoimidazolecarboxamide
           formyltransferase (EC 2.1.2.3) (AICAR transformylase);
           IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
           synthetase) (ATIC)]
          Length = 492

 Score =  166 bits (419), Expect = 6e-41
 Identities = 86/184 (46%), Positives = 112/184 (60%)
 Frame = +1

Query: 4   AGXNVTKVEQITHFPEMLDGRVKTLHPSIHGGILARRDQEHHLKALNEHGIGTFDVVVVN 183
           A   V  V  +THFPE++DGRVKTLHP++HGGILA R++  HL  L+E  I   D+VVVN
Sbjct: 41  ANVPVRSVSDLTHFPEIMDGRVKTLHPAVHGGILADRNKPQHLNELSEQHIDLIDMVVVN 100

Query: 184 LYPFYDKVTSGAISFEDGIENIDIGGPTLIRAAAKNHKDVLVVVDHRDYPALLKYLQEKQ 363
           LYPF   V +  ++ ++ IENIDIGGPT++RAAAKN+K V  +V   DY  +L  L+   
Sbjct: 101 LYPFQQTVANPDVTMDEAIENIDIGGPTMLRAAAKNYKHVTTIVHPADYQEVLTRLRNDS 160

Query: 364 VDPQFRRMLAWKAFQHVASYDSAVSEWLWKQSNSGDIFPPSFTVPLSMKSTLRYGENPHQ 543
           +D  +R+ L  K F+H A YD A+  +       GD            K TLRYGENP Q
Sbjct: 161 LDESYRQSLMIKVFEHTAEYDEAIVRFF-----KGD------------KETLRYGENPQQ 203

Query: 544 KAAF 555
            A F
Sbjct: 204 SAYF 207

---

>PUR9_STAAS (Q6GAE0) Bifunctional purine biosynthesis protein purH [Includes:|
           Phosphoribosylaminoimidazolecarboxamide
           formyltransferase (EC 2.1.2.3) (AICAR transformylase);
           IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
           synthetase) (ATIC)]
          Length = 492

 Score =  166 bits (419), Expect = 6e-41
 Identities = 86/184 (46%), Positives = 112/184 (60%)
 Frame = +1

Query: 4   AGXNVTKVEQITHFPEMLDGRVKTLHPSIHGGILARRDQEHHLKALNEHGIGTFDVVVVN 183
           A   V  V  +THFPE++DGRVKTLHP++HGGILA R++  HL  L+E  I   D+VVVN
Sbjct: 41  ANVPVRSVSDLTHFPEIMDGRVKTLHPAVHGGILADRNKPQHLNELSEQHIDLIDMVVVN 100

Query: 184 LYPFYDKVTSGAISFEDGIENIDIGGPTLIRAAAKNHKDVLVVVDHRDYPALLKYLQEKQ 363
           LYPF   V +  ++ ++ IENIDIGGPT++RAAAKN+K V  +V   DY  +L  L+   
Sbjct: 101 LYPFQQTVANPDVTMDEAIENIDIGGPTMLRAAAKNYKHVTTIVHPADYQEVLTRLRNDS 160

Query: 364 VDPQFRRMLAWKAFQHVASYDSAVSEWLWKQSNSGDIFPPSFTVPLSMKSTLRYGENPHQ 543
           +D  +R+ L  K F+H A YD A+  +       GD            K TLRYGENP Q
Sbjct: 161 LDESYRQSLMIKVFEHTAEYDEAIVRFF-----KGD------------KETLRYGENPQQ 203

Query: 544 KAAF 555
            A F
Sbjct: 204 SAYF 207

---

>PUR9_STAAR (Q6GI11) Bifunctional purine biosynthesis protein purH [Includes:|
           Phosphoribosylaminoimidazolecarboxamide
           formyltransferase (EC 2.1.2.3) (AICAR transformylase);
           IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
           synthetase) (ATIC)]
          Length = 492

 Score =  166 bits (419), Expect = 6e-41
 Identities = 86/184 (46%), Positives = 112/184 (60%)
 Frame = +1

Query: 4   AGXNVTKVEQITHFPEMLDGRVKTLHPSIHGGILARRDQEHHLKALNEHGIGTFDVVVVN 183
           A   V  V  +THFPE++DGRVKTLHP++HGGILA R++  HL  L+E  I   D+VVVN
Sbjct: 41  ANVPVRSVSDLTHFPEIMDGRVKTLHPAVHGGILADRNKPQHLNELSEQHIDLIDMVVVN 100

Query: 184 LYPFYDKVTSGAISFEDGIENIDIGGPTLIRAAAKNHKDVLVVVDHRDYPALLKYLQEKQ 363
           LYPF   V +  ++ ++ IENIDIGGPT++RAAAKN+K V  +V   DY  +L  L+   
Sbjct: 101 LYPFQQTVANPDVTMDEAIENIDIGGPTMLRAAAKNYKHVTTIVHPADYQEVLTRLRNDS 160

Query: 364 VDPQFRRMLAWKAFQHVASYDSAVSEWLWKQSNSGDIFPPSFTVPLSMKSTLRYGENPHQ 543
           +D  +R+ L  K F+H A YD A+  +       GD            K TLRYGENP Q
Sbjct: 161 LDESYRQSLMIKVFEHTAEYDEAIVRFF-----KGD------------KETLRYGENPQQ 203

Query: 544 KAAF 555
            A F
Sbjct: 204 SAYF 207

---

>PUR9_STAAC (Q5HH11) Bifunctional purine biosynthesis protein purH [Includes:|
           Phosphoribosylaminoimidazolecarboxamide
           formyltransferase (EC 2.1.2.3) (AICAR transformylase);
           IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
           synthetase) (ATIC)]
          Length = 492

 Score =  166 bits (419), Expect = 6e-41
 Identities = 86/184 (46%), Positives = 112/184 (60%)
 Frame = +1

Query: 4   AGXNVTKVEQITHFPEMLDGRVKTLHPSIHGGILARRDQEHHLKALNEHGIGTFDVVVVN 183
           A   V  V  +THFPE++DGRVKTLHP++HGGILA R++  HL  L+E  I   D+VVVN
Sbjct: 41  ANVPVRSVSDLTHFPEIMDGRVKTLHPAVHGGILADRNKPQHLNELSEQHIDLIDMVVVN 100

Query: 184 LYPFYDKVTSGAISFEDGIENIDIGGPTLIRAAAKNHKDVLVVVDHRDYPALLKYLQEKQ 363
           LYPF   V +  ++ ++ IENIDIGGPT++RAAAKN+K V  +V   DY  +L  L+   
Sbjct: 101 LYPFQQTVANPDVTMDEAIENIDIGGPTMLRAAAKNYKHVTTIVHPADYQEVLTRLRNDS 160

Query: 364 VDPQFRRMLAWKAFQHVASYDSAVSEWLWKQSNSGDIFPPSFTVPLSMKSTLRYGENPHQ 543
           +D  +R+ L  K F+H A YD A+  +       GD            K TLRYGENP Q
Sbjct: 161 LDESYRQSLMIKVFEHTAEYDEAIVRFF-----KGD------------KETLRYGENPQQ 203

Query: 544 KAAF 555
            A F
Sbjct: 204 SAYF 207

---

>PUR9_VIBVY (Q7MGT5) Bifunctional purine biosynthesis protein purH [Includes:|
           Phosphoribosylaminoimidazolecarboxamide
           formyltransferase (EC 2.1.2.3) (AICAR transformylase);
           IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
           synthetase) (ATIC)]
          Length = 530

 Score =  166 bits (419), Expect = 6e-41
 Identities = 87/195 (44%), Positives = 118/195 (60%), Gaps = 11/195 (5%)
 Frame = +1

Query: 7   GXNVTKVEQITHFPEMLDGRVKTLHPSIHGGILARRDQEHHLKALNEHGIGTFDVVVVNL 186
           G  VT+V   T FPEM+DGRVKTLHP +HGG+L RR Q+  + A  +HGI   D+VVVNL
Sbjct: 48  GIAVTEVSDYTGFPEMMDGRVKTLHPKVHGGVLGRRGQDDEVMA--KHGINPIDMVVVNL 105

Query: 187 YPFYDKVTSGAISFEDGIENIDIGGPTLIRAAAKNHKDVLVVVDHRDYPALLKYL--QEK 360
           YPF + V     +  D +ENIDIGGPT++R+AAKNHKDV +VV+  DY  ++  +   + 
Sbjct: 106 YPFAETVAKEGCTLADAVENIDIGGPTMVRSAAKNHKDVTIVVNASDYHRVITEMDANDT 165

Query: 361 QVDPQFRRMLAWKAFQHVASYDSAVSEWLW---------KQSNSGDIFPPSFTVPLSMKS 513
            +  + R  LA  AF+H A+YD  ++ +           K+ +    FP +F      K 
Sbjct: 166 SLTLETRFDLAIAAFEHTAAYDGMIANYFGTMVPSYGENKEGDEESKFPRTFNQQFIKKQ 225

Query: 514 TLRYGENPHQKAAFY 558
            +RYGEN HQ AAFY
Sbjct: 226 DMRYGENSHQAAAFY 240

---

>PUR9_VIBVU (Q8DD06) Bifunctional purine biosynthesis protein purH [Includes:|
           Phosphoribosylaminoimidazolecarboxamide
           formyltransferase (EC 2.1.2.3) (AICAR transformylase);
           IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
           synthetase) (ATIC)]
          Length = 530

 Score =  166 bits (419), Expect = 6e-41
 Identities = 87/195 (44%), Positives = 118/195 (60%), Gaps = 11/195 (5%)
 Frame = +1

Query: 7   GXNVTKVEQITHFPEMLDGRVKTLHPSIHGGILARRDQEHHLKALNEHGIGTFDVVVVNL 186
           G  VT+V   T FPEM+DGRVKTLHP +HGG+L RR Q+  + A  +HGI   D+VVVNL
Sbjct: 48  GIAVTEVSDYTGFPEMMDGRVKTLHPKVHGGVLGRRGQDDEVMA--KHGINPIDMVVVNL 105

Query: 187 YPFYDKVTSGAISFEDGIENIDIGGPTLIRAAAKNHKDVLVVVDHRDYPALLKYL--QEK 360
           YPF + V     +  D +ENIDIGGPT++R+AAKNHKDV +VV+  DY  ++  +   + 
Sbjct: 106 YPFAETVAKEGCTLADAVENIDIGGPTMVRSAAKNHKDVTIVVNASDYHRVITEMDANDT 165

Query: 361 QVDPQFRRMLAWKAFQHVASYDSAVSEWLW---------KQSNSGDIFPPSFTVPLSMKS 513
            +  + R  LA  AF+H A+YD  ++ +           K+ +    FP +F      K 
Sbjct: 166 SLTLETRFDLAIAAFEHTAAYDGMIANYFGTMVPSYGENKEGDEESKFPRTFNQQFIKKQ 225

Query: 514 TLRYGENPHQKAAFY 558
            +RYGEN HQ AAFY
Sbjct: 226 DMRYGENSHQAAAFY 240

---

>PUR9_STAAN (P67544) Bifunctional purine biosynthesis protein purH [Includes:|
           Phosphoribosylaminoimidazolecarboxamide
           formyltransferase (EC 2.1.2.3) (AICAR transformylase);
           IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
           synthetase) (ATIC)]
          Length = 492

 Score =  165 bits (418), Expect = 8e-41
 Identities = 86/184 (46%), Positives = 112/184 (60%)
 Frame = +1

Query: 4   AGXNVTKVEQITHFPEMLDGRVKTLHPSIHGGILARRDQEHHLKALNEHGIGTFDVVVVN 183
           A   V  V  +THFPE++DGRVKTLHP++HGGILA R++  HL  L+E  I   D+VVVN
Sbjct: 41  ANVPVRSVSDLTHFPEIMDGRVKTLHPAVHGGILADRNKPQHLNELSEQHIDLIDMVVVN 100

Query: 184 LYPFYDKVTSGAISFEDGIENIDIGGPTLIRAAAKNHKDVLVVVDHRDYPALLKYLQEKQ 363
           LYPF   V +  ++ ++ IENIDIGGPT++RAAAKN+K V  +V   DY  +L  L+   
Sbjct: 101 LYPFQQTVANPDVTMDEAIENIDIGGPTMLRAAAKNYKHVTTIVHPADYHEVLTRLRNDS 160

Query: 364 VDPQFRRMLAWKAFQHVASYDSAVSEWLWKQSNSGDIFPPSFTVPLSMKSTLRYGENPHQ 543
           +D  +R+ L  K F+H A YD A+  +       GD            K TLRYGENP Q
Sbjct: 161 LDESYRQSLMIKVFEHTAEYDEAIVRFF-----KGD------------KETLRYGENPQQ 203

Query: 544 KAAF 555
            A F
Sbjct: 204 SAYF 207

---

>PUR9_STAAM (P67543) Bifunctional purine biosynthesis protein purH [Includes:|
           Phosphoribosylaminoimidazolecarboxamide
           formyltransferase (EC 2.1.2.3) (AICAR transformylase);
           IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
           synthetase) (ATIC)]
          Length = 492

 Score =  165 bits (418), Expect = 8e-41
 Identities = 86/184 (46%), Positives = 112/184 (60%)
 Frame = +1

Query: 4   AGXNVTKVEQITHFPEMLDGRVKTLHPSIHGGILARRDQEHHLKALNEHGIGTFDVVVVN 183
           A   V  V  +THFPE++DGRVKTLHP++HGGILA R++  HL  L+E  I   D+VVVN
Sbjct: 41  ANVPVRSVSDLTHFPEIMDGRVKTLHPAVHGGILADRNKPQHLNELSEQHIDLIDMVVVN 100

Query: 184 LYPFYDKVTSGAISFEDGIENIDIGGPTLIRAAAKNHKDVLVVVDHRDYPALLKYLQEKQ 363
           LYPF   V +  ++ ++ IENIDIGGPT++RAAAKN+K V  +V   DY  +L  L+   
Sbjct: 101 LYPFQQTVANPDVTMDEAIENIDIGGPTMLRAAAKNYKHVTTIVHPADYHEVLTRLRNDS 160

Query: 364 VDPQFRRMLAWKAFQHVASYDSAVSEWLWKQSNSGDIFPPSFTVPLSMKSTLRYGENPHQ 543
           +D  +R+ L  K F+H A YD A+  +       GD            K TLRYGENP Q
Sbjct: 161 LDESYRQSLMIKVFEHTAEYDEAIVRFF-----KGD------------KETLRYGENPQQ 203

Query: 544 KAAF 555
            A F
Sbjct: 204 SAYF 207

---

>PUR9_PASMU (P57828) Bifunctional purine biosynthesis protein purH [Includes:|
           Phosphoribosylaminoimidazolecarboxamide
           formyltransferase (EC 2.1.2.3) (AICAR transformylase);
           IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
           synthetase) (ATIC)]
          Length = 533

 Score =  164 bits (415), Expect = 2e-40
 Identities = 89/204 (43%), Positives = 127/204 (62%), Gaps = 15/204 (7%)
 Frame = +1

Query: 7   GXNVTKVEQITHFPEMLDGRVKTLHPSIHGGILARRDQEHHLKALNEHGIGTFDVVVVNL 186
           G  VT+V   T FPEM+DGRVKTLHP +HGGIL RR  +  +  +++ GI   D+VVVNL
Sbjct: 48  GLAVTEVSDYTGFPEMMDGRVKTLHPKVHGGILGRRGTDDEV--MSQQGIEGIDMVVVNL 105

Query: 187 YPFYDKVTSGAISFEDGIENIDIGGPTLIRAAAKNHKDVLVVVDHRDYPALLKYLQEKQ- 363
           YPF   V     S E+ +ENIDIGGPT++R+AAKNH+DV +VV++ D+ A+L  + + Q 
Sbjct: 106 YPFAATVAKPNCSLEEAVENIDIGGPTMVRSAAKNHQDVAIVVNNSDFNAILAEMDQHQN 165

Query: 364 -VDPQFRRMLAWKAFQHVASYDSAVSEWLWK-------------QSNSGDIFPPSFTVPL 501
            +  + R  LA KAF+H A YD+ ++ +  +             ++  G  FP +  +  
Sbjct: 166 SLTLETRFDLAIKAFEHTAQYDAMIANYFGQLVKPYFVAEEEDAEAKCGQ-FPRTLNLNF 224

Query: 502 SMKSTLRYGENPHQKAAFYGDRSL 573
             K T+RYGEN HQKAAFY ++ +
Sbjct: 225 IRKQTMRYGENGHQKAAFYVEQDV 248

---

>PUR9_BIFLO (Q8G6B1) Bifunctional purine biosynthesis protein purH [Includes:|
           Phosphoribosylaminoimidazolecarboxamide
           formyltransferase (EC 2.1.2.3) (AICAR transformylase);
           IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
           synthetase) (ATIC)]
          Length = 545

 Score =  164 bits (414), Expect = 2e-40
 Identities = 97/206 (47%), Positives = 115/206 (55%), Gaps = 20/206 (9%)
 Frame = +1

Query: 7   GXNVTKVEQITHFPEMLDGRVKTLHPSIHGGILARRDQEHHLKALNEHGIGTFDVVVVNL 186
           G  VT+V  +T FPE LDGRVKTLHP IH GILA      H K L E GI  FD+VVVNL
Sbjct: 49  GVKVTEVSDVTGFPECLDGRVKTLHPYIHAGILADMTNPEHAKQLEEFGIKPFDLVVVNL 108

Query: 187 YPFYDKVTSGAISFEDGIENIDIGGPTLIRAAAKNHKDVLVVVDHRDYPALLKYLQE-KQ 363
           YPF D V SGA +  D IE IDIGGP+++R AAKNH  V +V D  DY  +   + +   
Sbjct: 109 YPFADTVRSGA-NEADTIEKIDIGGPSMVRGAAKNHATVAIVTDPADYALVASRVADGTG 167

Query: 364 VDPQFRRMLAWKAFQHVASYDSAVSEWL---WKQSNSGDI----------------FPPS 486
                R+ LA KAF H A+YD+ ++EW    W +  S D                 FP  
Sbjct: 168 FSLDERKWLAAKAFAHTAAYDATINEWTAKHWPKPASLDAVEVDKDDQGTEVDPAKFPAQ 227

Query: 487 FTVPLSMKSTLRYGENPHQKAAFYGD 564
           FT       TLRYGEN HQ+AA Y D
Sbjct: 228 FTRTWDRAHTLRYGENSHQQAALYID 253

---

>PUR9_MYCLE (Q9Z5H5) Bifunctional purine biosynthesis protein purH [Includes:|
           Phosphoribosylaminoimidazolecarboxamide
           formyltransferase (EC 2.1.2.3) (AICAR transformylase);
           IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
           synthetase) (ATIC)]
          Length = 527

 Score =  164 bits (414), Expect = 2e-40
 Identities = 91/191 (47%), Positives = 116/191 (60%), Gaps = 3/191 (1%)
 Frame = +1

Query: 7   GXNVTKVEQITHFPEMLDGRVKTLHPSIHGGILARRDQEHHLKALNEHGIGTFDVVVVNL 186
           G  VT VE++T FPE+LDGRVKTLHP +H G+LA   +  H  AL + GI  F++VVVNL
Sbjct: 55  GIAVTPVEELTGFPEVLDGRVKTLHPRVHAGLLADLRKPEHAAALEQLGIEAFELVVVNL 114

Query: 187 YPFYDKVTSGAISFEDGIENIDIGGPTLIRAAAKNHKDVLVVVDHRDYPALLKYLQEKQV 366
           YPF   V SGA + ++ +E IDIGG +++RAAAKNH  V VV D   Y  +L  +Q    
Sbjct: 115 YPFSQTVKSGA-TVDECVEQIDIGGSSMVRAAAKNHPSVAVVTDPLGYVGVLAAVQGGGF 173

Query: 367 DPQFRRMLAWKAFQHVASYDSAVSEWLWK---QSNSGDIFPPSFTVPLSMKSTLRYGENP 537
               R+MLA  AFQH+A Y+ AV+ W+            FP  F       + LRYGENP
Sbjct: 174 TLAERKMLASMAFQHIAEYEIAVASWMQSTLAPEQPPTAFPQWFGRSWRRSAILRYGENP 233

Query: 538 HQKAAFYGDRS 570
           HQ+AA Y D S
Sbjct: 234 HQQAALYSDPS 244

---

>PUR9_MYCPA (Q9RAJ5) Bifunctional purine biosynthesis protein purH [Includes:|
           Phosphoribosylaminoimidazolecarboxamide
           formyltransferase (EC 2.1.2.3) (AICAR transformylase);
           IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
           synthetase) (ATIC)]
          Length = 527

 Score =  163 bits (413), Expect = 3e-40
 Identities = 92/192 (47%), Positives = 120/192 (62%), Gaps = 6/192 (3%)
 Frame = +1

Query: 7   GXNVTKVEQITHFPEMLDGRVKTLHPSIHGGILARRDQEHHLKALNEHGIGTFDVVVVNL 186
           G  VT+VE +T FPE+LDGRVKTLHP +H G+LA   +  H  AL + GI  F++VVVNL
Sbjct: 55  GIPVTRVEVLTGFPEVLDGRVKTLHPRVHAGLLADLRKPEHAAALEQLGIAAFELVVVNL 114

Query: 187 YPFYDKVTSGAISFEDGIENIDIGGPTLIRAAAKNHKDVLVVVDHRDYPALLKYLQEKQV 366
           YPF + V SGA   ++ +E IDIGGP+++RAAAKNH  V VVVD   Y  +L  ++    
Sbjct: 115 YPFTETVDSGA-GIDECVEQIDIGGPSMVRAAAKNHPSVAVVVDPLGYDGVLAAVRHGGF 173

Query: 367 DPQFRRMLAWKAFQHVASYDSAVSEWLWKQSNSGDIFPPSFTVPLSM------KSTLRYG 528
               R+ LA  AFQH A YD AV+ W+  +S      PP+ T P  +       + LRYG
Sbjct: 174 TLAERKRLAALAFQHTADYDIAVATWM--ESTLAPEHPPT-TFPKWLGRSWRRSAMLRYG 230

Query: 529 ENPHQKAAFYGD 564
           ENPHQ+A+ Y D
Sbjct: 231 ENPHQQASLYSD 242

---

>PUR9_RHIME (Q92KX6) Bifunctional purine biosynthesis protein purH [Includes:|
           Phosphoribosylaminoimidazolecarboxamide
           formyltransferase (EC 2.1.2.3) (AICAR transformylase);
           IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
           synthetase) (ATIC)]
          Length = 536

 Score =  163 bits (413), Expect = 3e-40
 Identities = 82/185 (44%), Positives = 117/185 (63%)
 Frame = +1

Query: 4   AGXNVTKVEQITHFPEMLDGRVKTLHPSIHGGILARRDQEHHLKALNEHGIGTFDVVVVN 183
           AG  V+ V ++T FPE++DGRVKTLHP +HGG+LA RD   H  A++ HGI   D+ V+N
Sbjct: 56  AGLPVSDVSELTGFPEIMDGRVKTLHPGVHGGLLAIRDDAEHADAMSAHGITAIDLAVIN 115

Query: 184 LYPFYDKVTSGAISFEDGIENIDIGGPTLIRAAAKNHKDVLVVVDHRDYPALLKYLQEKQ 363
           LYPF ++V +    +   +ENIDIGGP +IRA+AKNH  V +V D  DY  LL+ + +  
Sbjct: 116 LYPF-EEVRAKGGDYPTTVENIDIGGPAMIRASAKNHAYVTIVTDPADYSPLLEEIADGA 174

Query: 364 VDPQFRRMLAWKAFQHVASYDSAVSEWLWKQSNSGDIFPPSFTVPLSMKSTLRYGENPHQ 543
               FR+ +A KA+   A+YD+ +S W  +  ++    P    +   ++  +RYGENPHQ
Sbjct: 175 TRYAFRQKMAAKAYARTAAYDATISNWFAEVLDTP--MPRHRVLGGLLREEMRYGENPHQ 232

Query: 544 KAAFY 558
           KA FY
Sbjct: 233 KAGFY 237

---

>PUR9_PSEAE (Q9HUV9) Bifunctional purine biosynthesis protein purH [Includes:|
           Phosphoribosylaminoimidazolecarboxamide
           formyltransferase (EC 2.1.2.3) (AICAR transformylase);
           IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
           synthetase) (ATIC)]
          Length = 535

 Score =  163 bits (412), Expect = 4e-40
 Identities = 87/192 (45%), Positives = 115/192 (59%), Gaps = 8/192 (4%)
 Frame = +1

Query: 7   GXNVTKVEQITHFPEMLDGRVKTLHPSIHGGILARRDQEHHLKALNEHGIGTFDVVVVNL 186
           G +  +V   T FPEM+DGRVKTLHP +HGGIL RRD +  +  + +HGI   D+V VNL
Sbjct: 51  GISAVEVADYTGFPEMMDGRVKTLHPKVHGGILGRRDLDGAV--MEQHGIKPIDLVAVNL 108

Query: 187 YPFYDKVTSGAISFEDGIENIDIGGPTLIRAAAKNHKDVLVVVDHRDYPALLKYLQEKQV 366
           YPF   V          IENIDIGGPT++R+AAKNHKDV +VV+  DY A+++ L+   +
Sbjct: 109 YPFEATVARPDCDLPTAIENIDIGGPTMVRSAAKNHKDVAIVVNAGDYAAVIESLKAGGL 168

Query: 367 DPQFRRMLAWKAFQHVASYDSAVSEWLWKQSNSGD--------IFPPSFTVPLSMKSTLR 522
               R  LA KAF+H ++YD  ++ +L     + D         FP +F         +R
Sbjct: 169 TYAQRFDLALKAFEHTSAYDGMIANYLGTIDQTRDTLGTADRGAFPRTFNSQFVKAQEMR 228

Query: 523 YGENPHQKAAFY 558
           YGENPHQ AAFY
Sbjct: 229 YGENPHQSAAFY 240

---

>PUR9_PSEPK (Q88DK3) Bifunctional purine biosynthesis protein purH [Includes:|
           Phosphoribosylaminoimidazolecarboxamide
           formyltransferase (EC 2.1.2.3) (AICAR transformylase);
           IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
           synthetase) (ATIC)]
          Length = 535

 Score =  162 bits (411), Expect = 5e-40
 Identities = 89/203 (43%), Positives = 118/203 (58%), Gaps = 13/203 (6%)
 Frame = +1

Query: 7   GXNVTKVEQITHFPEMLDGRVKTLHPSIHGGILARRDQEHHLKALNEHGIGTFDVVVVNL 186
           G N  +V   T F EM+DGRVKTLHP IHGGIL RR  +  +  +NEHGI   D+V VNL
Sbjct: 51  GVNAVEVADYTGFAEMMDGRVKTLHPKIHGGILGRRGTDDAI--MNEHGIKPIDLVAVNL 108

Query: 187 YPFYDKVTSGAISFEDGIENIDIGGPTLIRAAAKNHKDVLVVVDHRDYPALLKYLQEKQV 366
           YPF   ++         IENIDIGGPT++R+AAKNHKDV +VV+  DY  +++ L+   +
Sbjct: 109 YPFEATISKPGCDLPTAIENIDIGGPTMVRSAAKNHKDVAIVVNASDYAGIVEGLKAGGL 168

Query: 367 DPQFRRMLAWKAFQHVASYDSAVSEWLWKQSNSGDI--------FPPSFTVPLSMKSTLR 522
               R  L  KAF+H A+YD  ++ ++     + D         FP +F         +R
Sbjct: 169 TYAQRFDLMLKAFEHTAAYDGMIANYMGTIDQAKDTLSTEARSEFPRTFNSQFVKAQEMR 228

Query: 523 YGENPHQKAAFY-----GDRSLS 576
           YGENPHQ AAFY     G+ S+S
Sbjct: 229 YGENPHQSAAFYVEAKKGEASIS 251

---

>PUR9_CAMJR (Q5HUK6) Bifunctional purine biosynthesis protein purH [Includes:|
           Phosphoribosylaminoimidazolecarboxamide
           formyltransferase (EC 2.1.2.3) (AICAR transformylase);
           IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
           synthetase) (ATIC)]
          Length = 510

 Score =  162 bits (410), Expect = 7e-40
 Identities = 85/184 (46%), Positives = 119/184 (64%)
 Frame = +1

Query: 7   GXNVTKVEQITHFPEMLDGRVKTLHPSIHGGILARRDQEHHLKALNEHGIGTFDVVVVNL 186
           G  V +V   T  PE+ +GRVKTLHP IHGGIL +R  E+H+K   E+ I   D+V VNL
Sbjct: 41  GIKVMEVSDFTKSPELFEGRVKTLHPKIHGGILHKRSNENHIKQAKENEILGIDLVCVNL 100

Query: 187 YPFYDKVTSGAISFEDGIENIDIGGPTLIRAAAKNHKDVLVVVDHRDYPALLKYLQEKQV 366
           YPF  K T  +  F++ IENIDIGGP +IR+AAKN+KDV+V+ D  DY  +++ L++ Q+
Sbjct: 101 YPF-KKTTIMSDDFDEIIENIDIGGPAMIRSAAKNYKDVMVLCDPLDYEKVIETLKKGQI 159

Query: 367 DPQFRRMLAWKAFQHVASYDSAVSEWLWKQSNSGDIFPPSFTVPLSMKSTLRYGENPHQK 546
           D  FR  L  KA++H A+YD+ ++ ++ ++ N G  F  S  +        +YGENPHQK
Sbjct: 160 DENFRLNLMIKAYEHTANYDAYIANYMNERFNGG--FGASKFIVGQKVFDTKYGENPHQK 217

Query: 547 AAFY 558
            A Y
Sbjct: 218 GALY 221

---

>PUR9_HAEIN (P43852) Bifunctional purine biosynthesis protein purH [Includes:|
           Phosphoribosylaminoimidazolecarboxamide
           formyltransferase (EC 2.1.2.3) (AICAR transformylase);
           IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
           synthetase) (ATIC)]
          Length = 532

 Score =  162 bits (410), Expect = 7e-40
 Identities = 89/197 (45%), Positives = 117/197 (59%), Gaps = 14/197 (7%)
 Frame = +1

Query: 16  VTKVEQITHFPEMLDGRVKTLHPSIHGGILARRDQEHHLKALNEHGIGTFDVVVVNLYPF 195
           V +V   T FPEM+DGRVKTLHP +HGGIL RR  +  +  + +HGI   D+VVVNLYPF
Sbjct: 50  VIEVSDYTGFPEMMDGRVKTLHPKVHGGILGRRGTDDAI--MQQHGIEGIDMVVVNLYPF 107

Query: 196 YDKVTSGAISFEDGIENIDIGGPTLIRAAAKNHKDVLVVVDHRDYPALLKYLQEKQVDPQ 375
              V     +  D +ENIDIGGPT++R+AAKNHKDV +VV++ D+ A+L  + + Q    
Sbjct: 108 AATVAKPDCTLADAVENIDIGGPTMVRSAAKNHKDVAIVVNNHDFNAILAEMDQHQNSLT 167

Query: 376 F--RRMLAWKAFQHVASYDSAVSEWLWKQSNSGDI------------FPPSFTVPLSMKS 513
           F  R  LA KAF+H A YDS ++ +  +      I            FP +  +    K 
Sbjct: 168 FETRFDLAIKAFEHTAQYDSMIANYFGQLVKPYHIAEEEEANAKCGQFPRTLNLNFVRKQ 227

Query: 514 TLRYGENPHQKAAFYGD 564
            +RYGEN HQ AAFY D
Sbjct: 228 AMRYGENSHQNAAFYVD 244

---

>PUR9_CORGL (Q8NS21) Bifunctional purine biosynthesis protein purH [Includes:|
           Phosphoribosylaminoimidazolecarboxamide
           formyltransferase (EC 2.1.2.3) (AICAR transformylase);
           IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
           synthetase) (ATIC)]
          Length = 520

 Score =  162 bits (409), Expect = 9e-40
 Identities = 89/187 (47%), Positives = 116/187 (62%), Gaps = 3/187 (1%)
 Frame = +1

Query: 7   GXNVTKVEQITHFPEMLDGRVKTLHPSIHGGILARRDQEHHLKALNEHGIGTFDVVVVNL 186
           G  VT VE++T FPE L+GRVKTLHP +H GILA   +E HL+ L E  +  F +VVVNL
Sbjct: 49  GIPVTPVEELTGFPECLEGRVKTLHPKVHAGILADTRKEDHLRQLKELEVAPFQLVVVNL 108

Query: 187 YPFYDKVTSGAISFEDGIENIDIGGPTLIRAAAKNHKDVLVVVDHRDYPALLKYLQEKQV 366
           YPF + V SGA  F+  +E IDIGGP+++RAAAKNH  V VVV    Y  + + L+    
Sbjct: 109 YPFAETVASGA-DFDACVEQIDIGGPSMVRAAAKNHPSVAVVVSPNRYEDVQEALKTGGF 167

Query: 367 DPQFRRMLAWKAFQHVASYDSAVSEWLWKQ---SNSGDIFPPSFTVPLSMKSTLRYGENP 537
               R  LA +AF+H A+YD  V+ W+ +Q    +S   FP       ++  +LRYGENP
Sbjct: 168 SRAERTKLAAEAFRHTATYDVTVATWMSEQLAAEDSETEFPGWIGTTNTLSRSLRYGENP 227

Query: 538 HQKAAFY 558
           HQ AA Y
Sbjct: 228 HQSAALY 234

---

>PUR9_PSESM (Q87VR9) Bifunctional purine biosynthesis protein purH [Includes:|
           Phosphoribosylaminoimidazolecarboxamide
           formyltransferase (EC 2.1.2.3) (AICAR transformylase);
           IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
           synthetase) (ATIC)]
          Length = 534

 Score =  161 bits (407), Expect = 1e-39
 Identities = 88/192 (45%), Positives = 112/192 (58%), Gaps = 8/192 (4%)
 Frame = +1

Query: 7   GXNVTKVEQITHFPEMLDGRVKTLHPSIHGGILARRDQEHHLKALNEHGIGTFDVVVVNL 186
           G    +V   T F EM+DGRVKTLHP IHGGIL RR  +  +  +NEHGI   D+V VNL
Sbjct: 51  GVAAVEVADYTGFAEMMDGRVKTLHPKIHGGILGRRGIDDAI--MNEHGIKPIDLVAVNL 108

Query: 187 YPFYDKVTSGAISFEDGIENIDIGGPTLIRAAAKNHKDVLVVVDHRDYPALLKYLQEKQV 366
           YPF   V+         IENIDIGGPT++R+AAKNHKDV +VV+  DY  +L+ L+   +
Sbjct: 109 YPFEATVSKPGCDLPTAIENIDIGGPTMVRSAAKNHKDVAIVVNAGDYGQVLESLKAGGL 168

Query: 367 DPQFRRMLAWKAFQHVASYDSAVSEWLWKQSNSGDI--------FPPSFTVPLSMKSTLR 522
               R  L  KAF+H A+YD  ++ +L     + D         FP +F         +R
Sbjct: 169 TYAQRFDLMLKAFEHTAAYDGMIANYLGGVDQTADTLSTEGRSQFPRTFNTQFVKAQEMR 228

Query: 523 YGENPHQKAAFY 558
           YGENPHQ AAFY
Sbjct: 229 YGENPHQSAAFY 240

---

>PUR9_LEIXX (Q6AD62) Bifunctional purine biosynthesis protein purH [Includes:|
           Phosphoribosylaminoimidazolecarboxamide
           formyltransferase (EC 2.1.2.3) (AICAR transformylase);
           IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
           synthetase) (ATIC)]
          Length = 526

 Score =  160 bits (406), Expect = 2e-39
 Identities = 88/187 (47%), Positives = 110/187 (58%)
 Frame = +1

Query: 4   AGXNVTKVEQITHFPEMLDGRVKTLHPSIHGGILARRDQEHHLKALNEHGIGTFDVVVVN 183
           AG  VT V  +T FPE LDGRVKTLHP+IH G+LA      H + L + GI  F++VVVN
Sbjct: 59  AGHTVTDVASVTGFPESLDGRVKTLHPAIHSGLLADLRLASHEEQLKDLGIEPFELVVVN 118

Query: 184 LYPFYDKVTSGAISFEDGIENIDIGGPTLIRAAAKNHKDVLVVVDHRDYPALLKYLQEKQ 363
           LYPF + V SGA+  +D +E IDIGGP ++RA+AKNH +V +VV   DY  L   +    
Sbjct: 119 LYPFVETVASGAVD-DDVVEQIDIGGPAMVRASAKNHANVAIVVSPADYAGLAAAVAAGG 177

Query: 364 VDPQFRRMLAWKAFQHVASYDSAVSEWLWKQSNSGDIFPPSFTVPLSMKSTLRYGENPHQ 543
                RR LA +AF H A+YD AV+ W   ++         F V       LRYGEN HQ
Sbjct: 178 TTWGQRRELAARAFAHTAAYDGAVAAWFAGEAPDLSAVAERFEVRAEWGQPLRYGENAHQ 237

Query: 544 KAAFYGD 564
            AA Y D
Sbjct: 238 AAALYAD 244

---

>PUR9_CAMJE (Q9PNY2) Bifunctional purine biosynthesis protein purH [Includes:|
           Phosphoribosylaminoimidazolecarboxamide
           formyltransferase (EC 2.1.2.3) (AICAR transformylase);
           IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
           synthetase) (ATIC)]
          Length = 510

 Score =  160 bits (404), Expect = 3e-39
 Identities = 85/184 (46%), Positives = 118/184 (64%)
 Frame = +1

Query: 7   GXNVTKVEQITHFPEMLDGRVKTLHPSIHGGILARRDQEHHLKALNEHGIGTFDVVVVNL 186
           G  V +V   T  PE+ +GRVKTLHP IHGGIL +R  E+H+K   E+ I   D+V VNL
Sbjct: 41  GIKVIEVSDFTKSPELFEGRVKTLHPKIHGGILHKRSDENHIKQAKENEILGIDLVCVNL 100

Query: 187 YPFYDKVTSGAISFEDGIENIDIGGPTLIRAAAKNHKDVLVVVDHRDYPALLKYLQEKQV 366
           YPF  K T  +  F++ IENIDIGGP +IR+AAKN+KDV+V+ D  DY  +++ L++ Q 
Sbjct: 101 YPF-KKTTIMSDDFDEIIENIDIGGPAMIRSAAKNYKDVMVLCDPLDYEKVIETLKKGQN 159

Query: 367 DPQFRRMLAWKAFQHVASYDSAVSEWLWKQSNSGDIFPPSFTVPLSMKSTLRYGENPHQK 546
           D  FR  L  KA++H A+YD+ ++ ++ ++ N G  F  S  +        +YGENPHQK
Sbjct: 160 DENFRLNLMIKAYEHTANYDAYIANYMNERFNGG--FGASKFIVGQKVFDTKYGENPHQK 217

Query: 547 AAFY 558
            A Y
Sbjct: 218 GALY 221

---

>PUR9_SHEON (Q8EJM1) Bifunctional purine biosynthesis protein purH [Includes:|
           Phosphoribosylaminoimidazolecarboxamide
           formyltransferase (EC 2.1.2.3) (AICAR transformylase);
           IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
           synthetase) (ATIC)]
          Length = 543

 Score =  159 bits (402), Expect = 6e-39
 Identities = 92/210 (43%), Positives = 113/210 (53%), Gaps = 21/210 (10%)
 Frame = +1

Query: 7   GXNVTKVEQITHFPEMLDGRVKTLHPSIHGGILARRDQEHHLKALNEHGIGTFDVVVVNL 186
           G  V +V   T  PE++DGRVKTLHP +HGGILARR  + ++ A N   I   D+V VNL
Sbjct: 51  GVPVIEVSDYTGHPEIMDGRVKTLHPKVHGGILARRGLDENVMAANN--INAIDLVAVNL 108

Query: 187 YPFYDKVTSGAISFEDGIENIDIGGPTLIRAAAKNHKDVLVVVDHRDYPALLKYL--QEK 360
           YPF D V     + ED IENIDIGGPT++RAAAKNHKDV +VV+  DY  +L  +     
Sbjct: 109 YPFADTVAKAGCTLEDAIENIDIGGPTMVRAAAKNHKDVTIVVNAADYNRVLAEMAVNNG 168

Query: 361 QVDPQFRRMLAWKAFQHVASYDSAVSEWLWKQ-------------------SNSGDIFPP 483
                 R  LA  AF+H A YD  ++ +                       S  G  FP 
Sbjct: 169 STTHATRFDLAIAAFEHTAGYDGMIANYFGTMVPMHRVPAHSTDECFQDSLSVEGSKFPR 228

Query: 484 SFTVPLSMKSTLRYGENPHQKAAFYGDRSL 573
           +F   L  K  LRYGEN HQ AAFY D  +
Sbjct: 229 TFNTQLVKKQDLRYGENSHQAAAFYVDTKI 258

---

>PUR9_CORAM (Q9RHX6) Bifunctional purine biosynthesis protein purH [Includes:|
           Phosphoribosylaminoimidazolecarboxamide
           formyltransferase (EC 2.1.2.3) (AICAR transformylase);
           IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
           synthetase) (ATIC)]
          Length = 516

 Score =  158 bits (399), Expect = 1e-38
 Identities = 89/182 (48%), Positives = 109/182 (59%)
 Frame = +1

Query: 7   GXNVTKVEQITHFPEMLDGRVKTLHPSIHGGILARRDQEHHLKALNEHGIGTFDVVVVNL 186
           G NVT VE +T FPE L+GRVKTLHP +H GILA   +  HL  L E  I  F +VVVNL
Sbjct: 49  GINVTPVESLTGFPECLEGRVKTLHPRVHAGILADTRKPDHLNQLEELEIEPFQLVVVNL 108

Query: 187 YPFYDKVTSGAISFEDGIENIDIGGPTLIRAAAKNHKDVLVVVDHRDYPALLKYLQEKQV 366
           YPF + V SGA  F+  +E IDIGGP+++RAAAKNH  V VVVD   Y  + + + +   
Sbjct: 109 YPFKETVASGA-DFDGCVEQIDIGGPSMVRAAAKNHPSVAVVVDPARYGDIAEAVAQGGF 167

Query: 367 DPQFRRMLAWKAFQHVASYDSAVSEWLWKQSNSGDIFPPSFTVPLSMKSTLRYGENPHQK 546
           D   RR LA  AF+H A YD AVS W  +Q     +              LRYGENPHQ+
Sbjct: 168 DLAQRRQLAATAFKHTADYDVAVSGWFAQQLADDSVASAELE-----GDALRYGENPHQQ 222

Query: 547 AA 552
           A+
Sbjct: 223 AS 224

---

>PUR9_CHLTE (Q8KFK6) Bifunctional purine biosynthesis protein purH [Includes:|
           Phosphoribosylaminoimidazolecarboxamide
           formyltransferase (EC 2.1.2.3) (AICAR transformylase);
           IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
           synthetase) (ATIC)]
          Length = 523

 Score =  157 bits (398), Expect = 2e-38
 Identities = 88/204 (43%), Positives = 122/204 (59%), Gaps = 11/204 (5%)
 Frame = +1

Query: 4   AGXNVTKVEQITHFPEMLDGRVKTLHPSIHGGILARRDQEHHLKALNEHGIGTFDVVVVN 183
           AG     +  IT FPE++DGRVKTLHP IHGG+LA RD   H KA  E+GI   D+VVVN
Sbjct: 46  AGIVAQSISTITGFPEIMDGRVKTLHPKIHGGLLAVRDNAEHQKAARENGIQFIDLVVVN 105

Query: 184 LYPFYDKVTSGAISFEDGIENIDIGGPTLIRAAAKNHKDVLVVVDHRDYPALLKYLQEK- 360
           LYPF   +    ++FE+ IENIDIGGP+++R+AAKN++ V VV D  DY  +L  ++   
Sbjct: 106 LYPFEATIAKADVTFEEAIENIDIGGPSMLRSAAKNNESVTVVTDVADYATVLDEMRSNG 165

Query: 361 -QVDPQFRRMLAWKAFQHVASYDSAVSEWLWKQS---NSGDIFPPSFTVPLSMKSTLRYG 528
                  R  LA K +   + YD+A++ ++ K +    +GD    + T+ L  + ++RYG
Sbjct: 166 GATTRATRLTLAAKVYALTSRYDTAIAAYMAKAAGVKGAGD----TMTLKLEKELSMRYG 221

Query: 529 ENPHQKAAFY------GDRSLSLV 582
           ENPHQ A  Y      G RS S +
Sbjct: 222 ENPHQSAGLYKMDDGNGVRSFSAI 245

---

>PUR9_RHILO (Q98ES7) Bifunctional purine biosynthesis protein purH [Includes:|
           Phosphoribosylaminoimidazolecarboxamide
           formyltransferase (EC 2.1.2.3) (AICAR transformylase);
           IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
           synthetase) (ATIC)]
          Length = 538

 Score =  155 bits (392), Expect = 8e-38
 Identities = 87/193 (45%), Positives = 120/193 (62%), Gaps = 5/193 (2%)
 Frame = +1

Query: 4   AGXNVTKVEQITHFPEMLDGRVKTLHPSIHGGILARRDQEHHLKALNEHGIGTFDVVVVN 183
           AG  V  V ++T FPE++DGRVKTLHPS+HG +L  RD   H  A+ ++GI   D++V N
Sbjct: 56  AGLAVRDVSELTGFPEIMDGRVKTLHPSVHGALLGVRDDPEHAAAMRKYGIEPIDLLVSN 115

Query: 184 LYPFYDKVTSGAISFEDGIENIDIGGPTLIRAAAKNHKDVLVVVDHRDYPALLKYLQEK- 360
           LYPF +   SGA  +   +ENIDIGGP +IRA+AKNH  V +V D  DY ++L  L+   
Sbjct: 116 LYPFEEVRRSGA-DYAAIVENIDIGGPAMIRASAKNHAYVAIVTDPGDYASVLNALEMNI 174

Query: 361 -QVDPQFRRMLAWKAFQHVASYDSAVSEWLWKQSNSGDIFPPSF-TVPLSMKSTLRYGEN 534
             +   FR+ LA KAF   A+YD+A+S W    + + +I  P++      +   +RYGEN
Sbjct: 175 GSLSLDFRKKLAAKAFARTATYDAAISGWF---AEALEIEHPTWRAFGGRLTEVMRYGEN 231

Query: 535 PHQKAAFY--GDR 567
           PHQ A FY  GD+
Sbjct: 232 PHQSAGFYVNGDK 244

---

>PUR9_BUCAP (Q8KA70) Bifunctional purine biosynthesis protein purH [Includes:|
           Phosphoribosylaminoimidazolecarboxamide
           formyltransferase (EC 2.1.2.3) (AICAR transformylase);
           IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
           synthetase) (ATIC)]
          Length = 526

 Score =  155 bits (391), Expect = 1e-37
 Identities = 78/191 (40%), Positives = 122/191 (63%), Gaps = 5/191 (2%)
 Frame = +1

Query: 16  VTKVEQITHFPEMLDGRVKTLHPSIHGGILARRDQEHHLKALNEHGIGTFDVVVVNLYPF 195
           V ++   T+FPE+++GR+KTLHP I GGIL RR+++  +  L  H +   D+V+VN YPF
Sbjct: 51  VLEISDYTNFPEIMNGRLKTLHPKIIGGILGRREKDQKIMKL--HNLIPIDIVIVNFYPF 108

Query: 196 YDKVTSGAISFEDGIENIDIGGPTLIRAAAKNHKDVLVVVDHRDYPALLKYLQEKQVDPQ 375
                    + E+ I+NIDIGGPTL+RAAAKN+KDV+V+VD  D+ + ++ +    V  +
Sbjct: 109 EKIQNRKEFTIEEIIDNIDIGGPTLVRAAAKNYKDVIVIVDLSDFTSCIQLINTNTVSLE 168

Query: 376 FRRMLAWKAFQHVASYDSAVSEWL-----WKQSNSGDIFPPSFTVPLSMKSTLRYGENPH 540
            R  LA KAF++ A Y+  +S++      +++ +  +IFP  F +    K  LRYGEN H
Sbjct: 169 TRFDLATKAFKYTALYEEIISKYFLKKNPYRKKHQKNIFPNEFQLNFIKKQDLRYGENQH 228

Query: 541 QKAAFYGDRSL 573
           QK++FY ++ +
Sbjct: 229 QKSSFYIEKEI 239

---

>PUR92_YEAST (P38009) Bifunctional purine biosynthesis protein ADE17 [Includes:|
           Phosphoribosylaminoimidazolecarboxamide
           formyltransferase (EC 2.1.2.3) (AICAR transformylase);
           IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
           synthetase) (ATIC)]
          Length = 592

 Score =  153 bits (387), Expect = 3e-37
 Identities = 86/184 (46%), Positives = 108/184 (58%), Gaps = 1/184 (0%)
 Frame = +1

Query: 4   AGXNVTKVEQITHFPEMLDGRVKTLHPSIHGGILARRDQEHHLKALNEHGIGTFDVVVVN 183
           AG  +  V  ITH PEML GRVKTLHP++HGGILAR D +   K L E  I   D VV N
Sbjct: 45  AGFPIEDVSAITHAPEMLGGRVKTLHPAVHGGILAR-DIDSDEKDLKEQHIEKVDYVVCN 103

Query: 184 LYPFYDKVTSGAISFEDGIENIDIGGPTLIRAAAKNHKDVLVVVDHRDYPALLKYLQEK- 360
           LYPF + V    ++  + +E IDIGG TL+RAAAKNH  V ++ D +DY   L  L    
Sbjct: 104 LYPFKETVAKVGVTIPEAVEEIDIGGVTLLRAAAKNHARVTILSDPKDYSEFLSELSSNG 163

Query: 361 QVDPQFRRMLAWKAFQHVASYDSAVSEWLWKQSNSGDIFPPSFTVPLSMKSTLRYGENPH 540
           ++    R  LA KAF+H A YD+A+S++  KQ + G             + TLRYG NPH
Sbjct: 164 EISQDLRNRLALKAFEHTADYDAAISDFFRKQYSEG-----------QAQITLRYGANPH 212

Query: 541 QKAA 552
           QK A
Sbjct: 213 QKPA 216

---

>PUR9_XANCP (Q8PD47) Bifunctional purine biosynthesis protein purH [Includes:|
           Phosphoribosylaminoimidazolecarboxamide
           formyltransferase (EC 2.1.2.3) (AICAR transformylase);
           IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
           synthetase) (ATIC)]
          Length = 527

 Score =  150 bits (380), Expect = 2e-36
 Identities = 85/195 (43%), Positives = 110/195 (56%), Gaps = 8/195 (4%)
 Frame = +1

Query: 4   AGXNVTKVEQITHFPEMLDGRVKTLHPSIHGGILARRDQEHHLKALNEHGIGTFDVVVVN 183
           AG  V  V ++T FPEM+DGRVKTLHP +HGG+L R   +  + A  EHGI   D++V+N
Sbjct: 48  AGLPVKDVAELTGFPEMMDGRVKTLHPLVHGGLLGRAGVDEAVMA--EHGIAPIDLLVLN 105

Query: 184 LYPFYDKVTSGAISFEDGIENIDIGGPTLIRAAAKNHKDVLVVVDHRDYPALLKYLQEK- 360
           LYPF         +  D +ENIDIGGP ++R+AAKN   V V  D   Y  LL  L+   
Sbjct: 106 LYPFESVTAKADCTLADAVENIDIGGPAMLRSAAKNFARVAVATDPAQYADLLAELEANN 165

Query: 361 -QVDPQFRRMLAWKAFQHVASYDSAVSEWLWKQSNSGDIFPPSFTVPLSMKST------L 519
            Q+    R  L+  AF  VA YD+A+S +L   ++S +  P     P  + S       L
Sbjct: 166 GQLSAAQRFALSVAAFNRVAQYDAAISNYLSAVADSAESVPTRSPFPAQINSNFIKVMDL 225

Query: 520 RYGENPHQKAAFYGD 564
           RYGENPHQ  AFY D
Sbjct: 226 RYGENPHQSGAFYRD 240

---

>PUR9_XYLFT (Q87D58) Bifunctional purine biosynthesis protein purH [Includes:|
           Phosphoribosylaminoimidazolecarboxamide
           formyltransferase (EC 2.1.2.3) (AICAR transformylase);
           IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
           synthetase) (ATIC)]
          Length = 527

 Score =  150 bits (378), Expect = 3e-36
 Identities = 85/195 (43%), Positives = 109/195 (55%), Gaps = 8/195 (4%)
 Frame = +1

Query: 4   AGXNVTKVEQITHFPEMLDGRVKTLHPSIHGGILARRDQEHHLKALNEHGIGTFDVVVVN 183
           AG  V  V  +T FPEM+DGRVKTLHP +HGG+L R   +  + A  +HGI   D+++VN
Sbjct: 48  AGLPVQDVADLTDFPEMMDGRVKTLHPVVHGGLLGRAGIDDAVMA--KHGIAPIDLLIVN 105

Query: 184 LYPFYDKVTSGAISFEDGIENIDIGGPTLIRAAAKNHKDVLVVVDHRDYPALLKYLQ--E 357
           LYPF         +  D ++ IDIGGP ++R+AAKN   V V      YP LL  LQ   
Sbjct: 106 LYPFEQITAKKDCTLADAVDTIDIGGPAMLRSAAKNFARVAVATSPDQYPDLLAELQAHH 165

Query: 358 KQVDPQFRRMLAWKAFQHVASYDSAVSEWLWKQSNSGDIFPPSFTVPLSMKST------L 519
            Q+  + R  LA  AF HVA YD+A+S +L   S+     P     P  + +T      L
Sbjct: 166 GQLSAEKRFALAVAAFNHVAQYDAAISNYLSSVSDMHTTLPLRHEFPTQLNNTFVKMTDL 225

Query: 520 RYGENPHQKAAFYGD 564
           RYGENPHQ  AFY D
Sbjct: 226 RYGENPHQSGAFYRD 240

---

>PUR9_XANAC (Q8PQ19) Bifunctional purine biosynthesis protein purH [Includes:|
           Phosphoribosylaminoimidazolecarboxamide
           formyltransferase (EC 2.1.2.3) (AICAR transformylase);
           IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
           synthetase) (ATIC)]
          Length = 527

 Score =  150 bits (378), Expect = 3e-36
 Identities = 85/195 (43%), Positives = 111/195 (56%), Gaps = 8/195 (4%)
 Frame = +1

Query: 4   AGXNVTKVEQITHFPEMLDGRVKTLHPSIHGGILARRDQEHHLKALNEHGIGTFDVVVVN 183
           AG  V  V ++T FPEM+DGRVKTLHP +HGG+L R   +  + A  EHGI   D++V+N
Sbjct: 48  AGLPVKDVAELTGFPEMMDGRVKTLHPLVHGGLLGRAGVDEAVMA--EHGIVPIDLLVLN 105

Query: 184 LYPFYDKVTSGAISFEDGIENIDIGGPTLIRAAAKNHKDVLVVVDHRDYPALLKYLQ--E 357
           LYPF         +  D +ENIDIGGP ++R+AAKN   V V  D   Y  LL  L+  +
Sbjct: 106 LYPFESVTVKADCTLADAVENIDIGGPAMLRSAAKNFARVAVAADPAQYADLLVELEAND 165

Query: 358 KQVDPQFRRMLAWKAFQHVASYDSAVSEWLWKQSNSGDIFPPSFTVPLSMKST------L 519
            Q+    R  L+  AF  VA YD+A+S +L   ++S +  P     P  + S       L
Sbjct: 166 GQLSAAKRFALSVAAFNRVAQYDAAISNYLSAVADSAEAVPTRSPFPAQINSNFVKVMDL 225

Query: 520 RYGENPHQKAAFYGD 564
           RYGENPHQ  AFY D
Sbjct: 226 RYGENPHQSGAFYRD 240

---

>PUR9_XYLFA (Q9PC10) Bifunctional purine biosynthesis protein purH [Includes:|
           Phosphoribosylaminoimidazolecarboxamide
           formyltransferase (EC 2.1.2.3) (AICAR transformylase);
           IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
           synthetase) (ATIC)]
          Length = 527

 Score =  148 bits (374), Expect = 1e-35
 Identities = 84/195 (43%), Positives = 109/195 (55%), Gaps = 8/195 (4%)
 Frame = +1

Query: 4   AGXNVTKVEQITHFPEMLDGRVKTLHPSIHGGILARRDQEHHLKALNEHGIGTFDVVVVN 183
           AG  V  V  +T FPEM+DGRVKTLHP +HGG+L R   +  + A  +HGI   D++++N
Sbjct: 48  AGLPVQDVADLTGFPEMMDGRVKTLHPMVHGGLLGRAGIDDAVMA--KHGIAPIDLLILN 105

Query: 184 LYPFYDKVTSGAISFEDGIENIDIGGPTLIRAAAKNHKDVLVVVDHRDYPALLKYLQ--E 357
           LYPF         +  D ++ IDIGGP ++R+AAKN   V V      YP LL  LQ   
Sbjct: 106 LYPFEQITAKKDCTLADAVDTIDIGGPAMLRSAAKNFARVAVATSPDQYPDLLAELQAHH 165

Query: 358 KQVDPQFRRMLAWKAFQHVASYDSAVSEWLWKQSNSGDIFPPSFTVPLSMKST------L 519
            Q+  + R  LA  AF HVA YD+A+S +L   S+     P     P  + +T      L
Sbjct: 166 GQLSAEKRFALAVAAFNHVAQYDAAISNYLSSVSDMHTTLPLRHEFPAQLNNTFVKMTEL 225

Query: 520 RYGENPHQKAAFYGD 564
           RYGENPHQ  AFY D
Sbjct: 226 RYGENPHQTGAFYRD 240

---

>PUR9_ANASP (Q8YSJ2) Bifunctional purine biosynthesis protein purH [Includes:|
           Phosphoribosylaminoimidazolecarboxamide
           formyltransferase (EC 2.1.2.3) (AICAR transformylase);
           IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
           synthetase) (ATIC)]
          Length = 506

 Score =  147 bits (370), Expect = 3e-35
 Identities = 84/187 (44%), Positives = 110/187 (58%), Gaps = 2/187 (1%)
 Frame = +1

Query: 4   AGXNVTKVEQITHFPEMLDGRVKTLHPSIHGGILARRDQEHHLKALNEHGIGTFDVVVVN 183
           AG  VTKV   T  PE+L GRVKTLHP IHGGILARRD    L  L  + I   D+VVVN
Sbjct: 43  AGLPVTKVADYTGSPEILGGRVKTLHPRIHGGILARRDVASDLTDLENNQIRPIDLVVVN 102

Query: 184 LYPFYDKVTSGAISFEDGIENIDIGGPTLIRAAAKNHKDVLVVVDHRDYPALLKYLQEKQ 363
           LYPF   +    ++  + +E IDIGGP ++RA++KN   + V+ D   Y   L+ L++  
Sbjct: 103 LYPFESTIAKPGVTLAEAVEQIDIGGPAMLRASSKNFAHLTVLCDPAQYDEYLQELRQNN 162

Query: 364 --VDPQFRRMLAWKAFQHVASYDSAVSEWLWKQSNSGDIFPPSFTVPLSMKSTLRYGENP 537
                +FR+  A K F H ASYDSA++ +L     SG       T+  +   +LRYGENP
Sbjct: 163 GVASLEFRQKAALKGFLHTASYDSAIASYL-----SG---TQQHTLSGTELQSLRYGENP 214

Query: 538 HQKAAFY 558
           HQ AA+Y
Sbjct: 215 HQPAAWY 221

---

>PUR91_YEAST (P54113) Bifunctional purine biosynthesis protein ADE16 [Includes:|
           Phosphoribosylaminoimidazolecarboxamide
           formyltransferase (EC 2.1.2.3) (AICAR transformylase);
           IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
           synthetase) (ATIC)]
          Length = 591

 Score =  146 bits (369), Expect = 4e-35
 Identities = 84/184 (45%), Positives = 108/184 (58%), Gaps = 1/184 (0%)
 Frame = +1

Query: 4   AGXNVTKVEQITHFPEMLDGRVKTLHPSIHGGILARRDQEHHLKALNEHGIGTFDVVVVN 183
           AG  V  V  ITH PEML GRVKTLHP++H GILAR + E   K L E  I   D VV N
Sbjct: 45  AGFPVDDVSSITHAPEMLGGRVKTLHPAVHAGILAR-NLEGDEKDLKEQHIDKVDFVVCN 103

Query: 184 LYPFYDKVTSGAISFEDGIENIDIGGPTLIRAAAKNHKDVLVVVDHRDYPALLKYL-QEK 360
           LYPF + V    ++ ++ +E IDIGG TL+RAAAKNH  V ++ D  DY   L+ L ++ 
Sbjct: 104 LYPFKETVAKIGVTVQEAVEEIDIGGVTLLRAAAKNHSRVTILSDPNDYSIFLQDLSKDG 163

Query: 361 QVDPQFRRMLAWKAFQHVASYDSAVSEWLWKQSNSGDIFPPSFTVPLSMKSTLRYGENPH 540
           ++    R   A KAF+H A YD+A+S++  KQ + G    P           LRYG NPH
Sbjct: 164 EISQDLRNRFALKAFEHTADYDAAISDFFRKQYSEGKAQLP-----------LRYGCNPH 212

Query: 541 QKAA 552
           Q+ A
Sbjct: 213 QRPA 216

---

>PUR9_BUCAI (P57143) Bifunctional purine biosynthesis protein purH [Includes:|
           Phosphoribosylaminoimidazolecarboxamide
           formyltransferase (EC 2.1.2.3) (AICAR transformylase);
           IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
           synthetase) (ATIC)]
          Length = 525

 Score =  143 bits (361), Expect = 3e-34
 Identities = 74/192 (38%), Positives = 120/192 (62%), Gaps = 6/192 (3%)
 Frame = +1

Query: 16  VTKVEQITHFPEMLDGRVKTLHPSIHGGILARRDQEHHLKALNEHGIGTFDVVVVNLYPF 195
           VT++   T FPE++DGRVKTLHP I GGIL ++ ++  +  L  + I   D+V+VN YPF
Sbjct: 51  VTEISDYTKFPEIMDGRVKTLHPKIMGGILGQKQKDQEIMKL--YNICPIDIVIVNFYPF 108

Query: 196 YDKVTSGAISFEDGIENIDIGGPTLIRAAAKNHKDVLVVVDHRDYPALLKYLQEKQVDPQ 375
                      ++ + NIDIGGPTL+RA+AKN+K+V+V+VD  D+ + +  +    ++ +
Sbjct: 109 EKIKNIKKNDIDNVVNNIDIGGPTLVRASAKNYKNVIVIVDLDDFQSTIDSINNNTMNME 168

Query: 376 FRRMLAWKAFQHVASYDSAVSEW------LWKQSNSGDIFPPSFTVPLSMKSTLRYGENP 537
            R  LA KAF++ + Y+  +S++      L+K++N+  +FP         K  LRYGEN 
Sbjct: 169 KRFNLASKAFEYTSYYEQIISQYFIEQNSLYKKTNN-SLFPNEINFSFIKKQDLRYGENY 227

Query: 538 HQKAAFYGDRSL 573
           HQK++FY ++++
Sbjct: 228 HQKSSFYIEKNM 239

---

>PUR9_CHICK (P31335) Bifunctional purine biosynthesis protein PURH [Includes:|
           Phosphoribosylaminoimidazolecarboxamide
           formyltransferase (EC 2.1.2.3) (AICAR transformylase);
           IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
           synthetase) (ATIC)]
          Length = 593

 Score =  142 bits (358), Expect = 7e-34
 Identities = 83/186 (44%), Positives = 107/186 (57%), Gaps = 3/186 (1%)
 Frame = +1

Query: 4   AGXNVTKVEQITHFPEMLDGRVKTLHPSIHGGILARRDQEHHLKALNEHGIGTFDVVVVN 183
           AG  V  V  +T FPEML GRVKTLHP++H GILAR   E +   +N+       VVV N
Sbjct: 45  AGLPVRDVSDLTGFPEMLGGRVKTLHPAVHAGILARNIPEDNAD-MNKQDFSLVRVVVCN 103

Query: 184 LYPFYDKVTSGAISFEDGIENIDIGGPTLIRAAAKNHKDVLVVVDHRDYPALLKYL---Q 354
           LYPF   V+S  ++  + +E IDIGG  L+RAAAKNH  V VV D  DY ++ K +   +
Sbjct: 104 LYPFVKTVSSPGVTVPEAVEKIDIGGVALLRAAAKNHARVTVVCDPADYSSVAKEMAASK 163

Query: 355 EKQVDPQFRRMLAWKAFQHVASYDSAVSEWLWKQSNSGDIFPPSFTVPLSMKSTLRYGEN 534
           +K    + RR LA KAF H A YD+A+S++  K+ + G    P           LRYG N
Sbjct: 164 DKDTSVETRRHLALKAFTHTAQYDAAISDYFRKEYSKGVSQLP-----------LRYGMN 212

Query: 535 PHQKAA 552
           PHQ  A
Sbjct: 213 PHQSPA 218

---

>PUR9_BACTN (Q8A155) Bifunctional purine biosynthesis protein purH [Includes:|
           Phosphoribosylaminoimidazolecarboxamide
           formyltransferase (EC 2.1.2.3) (AICAR transformylase);
           IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
           synthetase) (ATIC)]
          Length = 507

 Score =  142 bits (357), Expect = 9e-34
 Identities = 83/182 (45%), Positives = 108/182 (59%), Gaps = 2/182 (1%)
 Frame = +1

Query: 25  VEQITHFPEMLDGRVKTLHPSIHGGILARRDQEHHLKALNEHGIGTFDVVVVNLYPFYDK 204
           VE +T +P +L GRVKTLHP I GGIL RRD E  ++ + ++ I   D+V+V+LYPF   
Sbjct: 54  VEDLTTYPSILGGRVKTLHPKIFGGILCRRDLEQDIQQIEKYEIPEIDLVIVDLYPFEAT 113

Query: 205 VTSGAISFEDGIENIDIGGPTLIRAAAKNHKDVLVVVDHRDYPALLKYLQEKQVDPQF-- 378
           V SGA S  D IE IDIGG +LIRAAAKN+ DV++V     Y  LL  L E         
Sbjct: 114 VASGA-SEADIIEKIDIGGISLIRAAAKNYNDVIIVASQAQYKPLLDMLMEHGATSSLEE 172

Query: 379 RRMLAWKAFQHVASYDSAVSEWLWKQSNSGDIFPPSFTVPLSMKSTLRYGENPHQKAAFY 558
           RR +A +AF   + YDSA+  +      S      +F   ++ +  LRYGENPHQK  FY
Sbjct: 173 RRWMAKEAFAVSSHYDSAIFNYFDAGEGS------AFRCSVNNQKQLRYGENPHQKGYFY 226

Query: 559 GD 564
           G+
Sbjct: 227 GN 228

---

>PUR9_SYNY3 (P74741) Bifunctional purine biosynthesis protein purH [Includes:|
           Phosphoribosylaminoimidazolecarboxamide
           formyltransferase (EC 2.1.2.3) (AICAR transformylase);
           IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
           synthetase) (ATIC)]
          Length = 511

 Score =  141 bits (356), Expect = 1e-33
 Identities = 81/186 (43%), Positives = 107/186 (57%), Gaps = 1/186 (0%)
 Frame = +1

Query: 4   AGXNVTKVEQITHFPEMLDGRVKTLHPSIHGGILARRDQEHHLKALNEHGIGTFDVVVVN 183
           AG  VTKV   T  PE+L GRVKTLHP IHGGILARRD       L  + I   D+VVVN
Sbjct: 43  AGVPVTKVSDYTGAPEILGGRVKTLHPRIHGGILARRDLPSDQADLEANDIRPLDLVVVN 102

Query: 184 LYPFYDKVTSGAISFEDGIENIDIGGPTLIRAAAKNHKDVLVVVDHRDYPALLKYLQEK- 360
           LYPF   +    ++  + +E IDIGGP +IRA AKN     V+ +   Y A L+ LQE+ 
Sbjct: 103 LYPFEQTIAKPGVTVAEAVEQIDIGGPAMIRATAKNFAHTTVLTNPNQYEAYLQALQEQG 162

Query: 361 QVDPQFRRMLAWKAFQHVASYDSAVSEWLWKQSNSGDIFPPSFTVPLSMKSTLRYGENPH 540
           ++    R+  A +AF    +YD A++ +      SGD     F +  +++  LRYGENPH
Sbjct: 163 EIPLALRQQFAGEAFALTNAYDQAIANYF--SGLSGD-SANQFGLSGTLRQPLRYGENPH 219

Query: 541 QKAAFY 558
           Q A +Y
Sbjct: 220 QSAGWY 225

---

>PUR9_HUMAN (P31939) Bifunctional purine biosynthesis protein PURH [Includes:|
           Phosphoribosylaminoimidazolecarboxamide
           formyltransferase (EC 2.1.2.3) (AICAR transformylase);
           IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
           synthetase) (ATIC)]
          Length = 592

 Score =  138 bits (348), Expect = 1e-32
 Identities = 83/186 (44%), Positives = 102/186 (54%), Gaps = 3/186 (1%)
 Frame = +1

Query: 4   AGXNVTKVEQITHFPEMLDGRVKTLHPSIHGGILARRDQEHHLKALNEHGIGTFDVVVVN 183
           AG  V  V ++T FPEML GRVKTLHP++H GILAR   E +   +         VV  N
Sbjct: 44  AGLAVRDVSELTGFPEMLGGRVKTLHPAVHAGILARNIPEDNAD-MARLDFNLIRVVACN 102

Query: 184 LYPFYDKVTSGAISFEDGIENIDIGGPTLIRAAAKNHKDVLVVVDHRDYPALLKYLQ--- 354
           LYPF   V S  ++ E+ +E IDIGG TL+RAAAKNH  V VV +  DY  +   +Q   
Sbjct: 103 LYPFVKTVASPGVTVEEAVEQIDIGGVTLLRAAAKNHARVTVVCEPEDYVVVSTEMQSSE 162

Query: 355 EKQVDPQFRRMLAWKAFQHVASYDSAVSEWLWKQSNSGDIFPPSFTVPLSMKSTLRYGEN 534
            K    + RR LA KAF H A YD A+S++  KQ + G    P           LRYG N
Sbjct: 163 SKDTSLETRRQLALKAFTHTAQYDEAISDYFRKQYSKGVSQMP-----------LRYGMN 211

Query: 535 PHQKAA 552
           PHQ  A
Sbjct: 212 PHQTPA 217

---

>PUR9_SCHPO (O74928) Bifunctional purine biosynthesis protein ade10 [Includes:|
           Phosphoribosylaminoimidazolecarboxamide
           formyltransferase (EC 2.1.2.3) (AICAR transformylase);
           IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
           synthetase) (ATIC)]
          Length = 585

 Score =  136 bits (342), Expect = 5e-32
 Identities = 81/184 (44%), Positives = 105/184 (57%), Gaps = 1/184 (0%)
 Frame = +1

Query: 4   AGXNVTKVEQITHFPEMLDGRVKTLHPSIHGGILARRDQEHHLKALNEHGIGTFDVVVVN 183
           +G  V  V  IT+ PE+L GRVKTLHP++HGGILAR D     K L E  I   D+VV N
Sbjct: 40  SGMEVADVSSITNAPEILGGRVKTLHPAVHGGILAR-DIPSDEKDLVEQSIEKIDIVVCN 98

Query: 184 LYPFYDKVTSGAISFEDGIENIDIGGPTLIRAAAKNHKDVLVVVDHRDYPALL-KYLQEK 360
           LYPF + +    ++  + +E IDIGG TL+RAAAKNH  V ++ D  DY     K+L +K
Sbjct: 99  LYPFRETIAKPNVTIPEAVEEIDIGGVTLLRAAAKNHARVTILSDPADYATFTDKFLSDK 158

Query: 361 QVDPQFRRMLAWKAFQHVASYDSAVSEWLWKQSNSGDIFPPSFTVPLSMKSTLRYGENPH 540
                 R   A KAF   ASYD+A++++  KQ  +G             + TLRYG NPH
Sbjct: 159 LTQDD-RNTYALKAFASTASYDAAITDYFRKQYAAG-----------VDQLTLRYGANPH 206

Query: 541 QKAA 552
           Q  A
Sbjct: 207 QSPA 210

---

>PUR9_MOUSE (Q9CWJ9) Bifunctional purine biosynthesis protein PURH [Includes:|
           Phosphoribosylaminoimidazolecarboxamide
           formyltransferase (EC 2.1.2.3) (AICAR transformylase);
           IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
           synthetase) (ATIC)]
          Length = 592

 Score =  134 bits (337), Expect = 2e-31
 Identities = 83/186 (44%), Positives = 100/186 (53%), Gaps = 3/186 (1%)
 Frame = +1

Query: 4   AGXNVTKVEQITHFPEMLDGRVKTLHPSIHGGILARRDQEHHLKALNEHGIGTFDVVVVN 183
           AG  V  V ++T FPEML GRVKTLHP++H GILAR   E     +         VVV N
Sbjct: 44  AGLAVRDVSELTGFPEMLGGRVKTLHPAVHAGILARNIPEDAAD-MARLDFNLVRVVVCN 102

Query: 184 LYPFYDKVTSGAISFEDGIENIDIGGPTLIRAAAKNHKDVLVVVDHRDYPALLKYL---Q 354
           LYPF   V S  ++ E  +E IDIGG TL+RAAAKNH  V VV +  DY  +   +    
Sbjct: 103 LYPFVKTVASPDVTVEAAVEQIDIGGVTLLRAAAKNHARVTVVCEPEDYAGVAAEMHGSD 162

Query: 355 EKQVDPQFRRMLAWKAFQHVASYDSAVSEWLWKQSNSGDIFPPSFTVPLSMKSTLRYGEN 534
            K    + RR LA KAF H A YD A+S++  KQ + G    P           LRYG N
Sbjct: 163 SKDTSLETRRHLALKAFTHTAQYDEAISDYFRKQYSKGISQMP-----------LRYGMN 211

Query: 535 PHQKAA 552
           PHQ  A
Sbjct: 212 PHQTPA 217

---

>PUR9_WIGBR (Q8D244) Bifunctional purine biosynthesis protein purH [Includes:|
           Phosphoribosylaminoimidazolecarboxamide
           formyltransferase (EC 2.1.2.3) (AICAR transformylase);
           IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
           synthetase) (ATIC)]
          Length = 529

 Score =  127 bits (318), Expect = 3e-29
 Identities = 77/193 (39%), Positives = 103/193 (53%), Gaps = 11/193 (5%)
 Frame = +1

Query: 19  TKVEQITHFPEMLDGRVKTLHPSIHGGILARRDQEHHLKALNEHGIGTFDVVVVNLYPFY 198
           T V +  + PE+++GRVKTLHP IHGGIL+     +  K LN   I   D+V+ N YPF 
Sbjct: 53  TSVSEYINHPEIINGRVKTLHPKIHGGILSNNKNINENKNLN---IKKIDMVITNFYPFK 109

Query: 199 DKVTSGAISFEDGIENIDIGGPTLIRAAAKNHKDVLVVVDHRDYPALLKYLQEKQVDPQF 378
            KV    I  E+ I+NIDIGG  L R+AAKN+K V VVV+   Y  L   + +      F
Sbjct: 110 KKVKKENIKIENIIDNIDIGGVALARSAAKNYKYVTVVVNINQYSKLSSEMDKNSGSVSF 169

Query: 379 RRMLAWK--AFQHVASYDSAVSEWL---------WKQSNSGDIFPPSFTVPLSMKSTLRY 525
           +    +   AFQ+  SYD  +  +           K++     FP  F++  S K  + Y
Sbjct: 170 KTRFYFSTLAFQYSYSYDKEIFNYFNKIYFKEIELKKNLKNKKFPELFSISFSKKEDVLY 229

Query: 526 GENPHQKAAFYGD 564
           GEN HQKAAFY D
Sbjct: 230 GENYHQKAAFYTD 242

---

>PUR9_BUCBP (Q89B23) Bifunctional purine biosynthesis protein purH [Includes:|
           Phosphoribosylaminoimidazolecarboxamide
           formyltransferase (EC 2.1.2.3) (AICAR transformylase);
           IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
           synthetase) (ATIC)]
          Length = 529

 Score =  120 bits (302), Expect = 2e-27
 Identities = 67/193 (34%), Positives = 109/193 (56%), Gaps = 9/193 (4%)
 Frame = +1

Query: 19  TKVEQITHFPEMLDGRVKTLHPSIHGGILARRDQEHHLKALNEHGIGTFDVVVVNLYPFY 198
           T +   T+FPE+++GR+KTLH  I+  ILA+   +H  K + ++ I   D+VV+N YPF 
Sbjct: 52  TDITNYTNFPEIMNGRIKTLHHKIYASILAQ--PKHDKKTIEKYNIILMDIVVINFYPFE 109

Query: 199 DKVTSGAISFEDGIENIDIGGPTLIRAAAKNHKDVLVVVDHRDYPALLK--YLQEKQVDP 372
           +   +  +   D IE+IDIGGP ++RAAAKN+K+VLVV     Y +++    L    +  
Sbjct: 110 EASNNTNLHLNDIIEHIDIGGPAIVRAAAKNYKNVLVVTQPNLYQSIVNEMNLNNNIISE 169

Query: 373 QFRRMLAWKAFQHVASYDSAVSEWLWKQSNS-------GDIFPPSFTVPLSMKSTLRYGE 531
             +   A  AF+H  +YD+ + ++L K++ +         + P   T+    K  L YGE
Sbjct: 170 TTKLKFATIAFKHTMNYDNNIYQYLSKKNKTVPKNTQLQTLLPSHLTINFKKKQDLCYGE 229

Query: 532 NPHQKAAFYGDRS 570
           N  Q+A++Y + S
Sbjct: 230 NKQQQASWYTNTS 242

---

>PUR9_THEMA (Q9X0X6) Bifunctional purine biosynthesis protein purH [Includes:|
           Phosphoribosylaminoimidazolecarboxamide
           formyltransferase (EC 2.1.2.3) (AICAR transformylase);
           IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
           synthetase) (ATIC)]
          Length = 452

 Score = 71.6 bits (174), Expect = 2e-12
 Identities = 61/193 (31%), Positives = 79/193 (40%), Gaps = 1/193 (0%)
 Frame = +1

Query: 7   GXNVTKVEQITHFPEMLDGRVKTLHPSIHGGILARRDQEHHLKALNEHGIGTFDVVVVNL 186
           G     V  IT F  +L G VKTLHP I  GIL    +              +DVV V+L
Sbjct: 42  GIEANDVSTITGFENLLGGLVKTLHPEIFAGILGPEPR--------------WDVVFVDL 87

Query: 187 YPFYDKVTSGAISFEDGIENIDIGGPTLIRAAAKNHKDVLVVVDHRDYPALLKYLQEKQV 366
           YP  D               IDIGG  L+RAAAKN K V    D       ++       
Sbjct: 88  YPPPD---------------IDIGGVALLRAAAKNWKKVKPAFDMETLKLAIEI-----D 127

Query: 367 DPQFRRMLAWKAFQHVASYDSAVSEWLWKQSNSGDIFPPSFTVPLSMKS-TLRYGENPHQ 543
           D + R+ LA   F   + YDS             + F    ++    +   LRYGENPH+
Sbjct: 128 DEETRKYLAGMTFAFTSVYDSI----------RANQFVEGISLAFKREDLQLRYGENPHE 177

Query: 544 KAAFYGDRSLSLV 582
           KA  YG  +  ++
Sbjct: 178 KAFVYGKPAFEIL 190

---

>ITB4_RAT (Q64632) Integrin beta-4 precursor (GP150) (CD104 antigen)|
          Length = 1807

 Score = 34.7 bits (78), Expect = 0.21
 Identities = 27/103 (26%), Positives = 47/103 (45%), Gaps = 5/103 (4%)
 Frame = +1

Query: 16   VTKVEQITHFPEMLDGRVKTLHPSIHGGILARRDQEHHLKALNEHGIGTFDVVVVNLYPF 195
            V K++Q T F +  +   K  H  +   +LA R  +  L  L E  +       + + P 
Sbjct: 863  VHKLQQ-TKFRQQPNAGKKQDHTIVDTVLLAPRSAKQSLLKLTEKQVEQGSFHELKVAPG 921

Query: 196  YDKVTS-----GAISFEDGIENIDIGGPTLIRAAAKNHKDVLV 309
            Y  +T+     G + F++G+E +D+  P  IR    + K +LV
Sbjct: 922  YYTLTAEQDARGMVEFQEGVELVDVRVPLFIRPEDDDEKQLLV 964

---

>VP75_SHV21 (P11282) Probable membrane antigen 75 (Tegument protein)|
          Length = 1299

 Score = 34.3 bits (77), Expect = 0.27
 Identities = 15/37 (40%), Positives = 20/37 (54%)
 Frame = -3

Query: 452 FHNHSETAES*EATCWKAFHASILRNCGSTCFSCRYF 342
           FH HS T       C   FH+S+L N  +T F+C Y+
Sbjct: 273 FHVHSSTRTMGRQCCDYLFHSSLLPNGNTTAFACGYY 309

---

>GBF_DICDI (P36417) G-box-binding factor (GBF)|
          Length = 708

 Score = 32.7 bits (73), Expect = 0.78
 Identities = 19/66 (28%), Positives = 32/66 (48%)
 Frame = -1

Query: 337 EQGNHDDPQQQEHPYDSSLQLGSM*AHQYQYFQCHPRKKLHQR*PYHRMDTNSPQPHQMS 158
           +Q +H   QQQ+H     +Q   +  HQ+Q+ Q   +++ HQ+  + +      Q HQ  
Sbjct: 165 QQQHHQQMQQQQH--HQQMQHHQLQQHQHQHQQ-QQQQQQHQQQHHQQQQQQQQQHHQQQ 221

Query: 157 LCHAHS 140
             H HS
Sbjct: 222 QHHQHS 227

---

>PHLA1_MOUSE (Q62392) Pleckstrin homology-like domain family A member 1 (T-cell|
           death-associated gene 51 protein) (Proline- and
           glutamine-rich protein) (PQR protein)
          Length = 261

 Score = 32.7 bits (73), Expect = 0.78
 Identities = 21/61 (34%), Positives = 22/61 (36%)
 Frame = -1

Query: 316 PQQQEHPYDSSLQLGSM*AHQYQYFQCHPRKKLHQR*PYHRMDTNSPQPHQMSLCHAHSM 137
           PQ Q  P     QL     H Y +   HP    HQ    H      P PH   L HAH  
Sbjct: 189 PQPQPQPQPQPQQL-----HSYPHPHPHPYSHPHQHPHPHPHPHPHPHPHPYQLQHAHQP 243

Query: 136 L 134
           L
Sbjct: 244 L 244

---

>ITB4_HUMAN (P16144) Integrin beta-4 precursor (GP150) (CD104 antigen)|
          Length = 1822

 Score = 31.6 bits (70), Expect = 1.7
 Identities = 26/103 (25%), Positives = 47/103 (45%), Gaps = 5/103 (4%)
 Frame = +1

Query: 16   VTKVEQITHFPEMLDGRVKTLHPSIHGGILARRDQEHHLKALNEHGIGTFDVVVVNLYPF 195
            V K++Q T F +  +   K  H  +   ++A R  +  L  L E  +       + + P 
Sbjct: 861  VHKLQQ-TKFRQQPNAGKKQDHTIVDTVLMAPRSAKPALLKLTEKQVEQRAFHDLKVAPG 919

Query: 196  YDKVTS-----GAISFEDGIENIDIGGPTLIRAAAKNHKDVLV 309
            Y  +T+     G + F++G+E +D+  P  IR    + K +LV
Sbjct: 920  YYTLTADQDARGMVEFQEGVELVDVRVPLFIRPEDDDEKQLLV 962

---

>TRPA_STAES (Q8CPB0) Tryptophan synthase alpha chain (EC 4.2.1.20)|
          Length = 243

 Score = 31.2 bits (69), Expect = 2.3
 Identities = 19/45 (42%), Positives = 24/45 (53%)
 Frame = +1

Query: 124 HHLKALNEHGIGTFDVVVVNLYPFYDKVTSGAISFEDGIENIDIG 258
           HHLK L E+G    D+V + + PF D V  G I  + G   ID G
Sbjct: 17  HHLKTLTENGA---DIVEIGV-PFSDPVADGPIIMKAGRNAIDEG 57

---

>TRPA_STAEQ (Q5HPG9) Tryptophan synthase alpha chain (EC 4.2.1.20)|
          Length = 243

 Score = 31.2 bits (69), Expect = 2.3
 Identities = 19/45 (42%), Positives = 24/45 (53%)
 Frame = +1

Query: 124 HHLKALNEHGIGTFDVVVVNLYPFYDKVTSGAISFEDGIENIDIG 258
           HHLK L E+G    D+V + + PF D V  G I  + G   ID G
Sbjct: 17  HHLKTLTENGA---DIVEIGV-PFSDPVADGPIIMKAGRNAIDEG 57

---

>SAM4_YEAST (Q08985) Homocysteine S-methyltransferase 2 (EC 2.1.1.10)|
           (S-methylmethionine:homocysteine methyltransferase 2)
           (SMM:Hcy S-methyltransferase 2) (S-adenosylmethionine
           metabolism protein 4)
          Length = 325

 Score = 31.2 bits (69), Expect = 2.3
 Identities = 17/40 (42%), Positives = 25/40 (62%)
 Frame = +2

Query: 197 MIRLPLVQFLSRMALKILILVGLH*SELQRRIIRMFLLLW 316
           M RLPL QFL+    K+L+L G   +EL+ R I++   +W
Sbjct: 1   MARLPLKQFLADNPKKVLVLDGGQGTELENRGIKVANPVW 40

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>EF2_SCHPO (O14460) Elongation factor 2 (EF-2)|
          Length = 842

 Score = 30.8 bits (68), Expect = 3.0
 Identities = 25/98 (25%), Positives = 43/98 (43%)
 Frame = +1

Query: 202 KVTSGAISFEDGIENIDIGGPTLIRAAAKNHKDVLVVVDHRDYPALLKYLQEKQVDPQFR 381
           +VT GA+   D IE + +   T++R A       +VVV+  D   L   + ++++   F 
Sbjct: 120 RVTDGALVVVDTIEGVCVQTETVLRQALGERIRPVVVVNKVDRALLELQISQEELYQNFA 179

Query: 382 RMLAWKAFQHVASYDSAVSEWLWKQSNSGDIFPPSFTV 495
           R+        V S +  +S +  K      +FP   TV
Sbjct: 180 RV--------VESVNVVISTYYDKVLGDCQVFPDKGTV 209

---

>YL766_MIMIV (Q5UPQ2) Putative ankyrin repeat protein L766|
          Length = 636

 Score = 30.0 bits (66), Expect = 5.0
 Identities = 18/76 (23%), Positives = 32/76 (42%)
 Frame = -2

Query: 315 HNNKNILMILRCSSDQCRPTNINIFNAILERNCTRGNLIIEWIQIHHNHIKCPYAMLIQC 136
           +N+  +L ++  S       NI +F  +LE NC             +N++   +   I C
Sbjct: 516 YNSIELLFVVTLSE------NIELFKLLLEINCN-----------DNNYLSWAFVFSIGC 558

Query: 135 FKMMLLVSSGKNATVY 88
           FK+M  +    N  +Y
Sbjct: 559 FKLMKYIVDNYNIDIY 574

---

>CAUP_DROME (P54269) Homeobox protein caupolican|
          Length = 693

 Score = 30.0 bits (66), Expect = 5.0
 Identities = 21/81 (25%), Positives = 30/81 (37%)
 Frame = -1

Query: 418 KPRAGKLSMPASCGTAGPLAFLVDISIEQGNHDDPQQQEHPYDSSLQLGSM*AHQYQYFQ 239
           KP+   ++  A+C T  P A  +  +    +  D Q    P     Q       Q Q   
Sbjct: 459 KPKIWSVADTAACKTPPPTAAYLGQNFYPPSSADQQLPHQPLQQHQQQQLQQLQQQQQHH 518

Query: 238 CHPRKKLHQR*PYHRMDTNSP 176
            HP    H   P+H M+  SP
Sbjct: 519 HHP----HHHHPHHSMELGSP 535

---

>DOA_DROME (P49762) Serine/threonine-protein kinase Doa (EC 2.7.12.1) (Protein|
           darkener of apricot)
          Length = 832

 Score = 29.6 bits (65), Expect = 6.6
 Identities = 23/75 (30%), Positives = 32/75 (42%), Gaps = 2/75 (2%)
 Frame = -1

Query: 334 QGNHDDPQQQEHPYDSSLQLGSM*AHQYQYFQCHPRKKLHQR*PYHRMDTNSPQP--HQM 161
           Q     PQQQ+H + SS  +G M  + Y   +   RK L    PY     N  QP  +Q 
Sbjct: 297 QQQQQHPQQQQHQH-SSFGVGMMSRNYYNMPKQPERKPLQTFDPYAYPKPNQMQPVKYQQ 355

Query: 160 SLCHAHSML*DDAPG 116
              H H+   + + G
Sbjct: 356 QQQHPHTQFQNASAG 370

---

>Y143_MYCPN (P75143) Hypothetical protein MPN143 (E07_orf175)|
          Length = 175

 Score = 29.3 bits (64), Expect = 8.6
 Identities = 19/60 (31%), Positives = 29/60 (48%), Gaps = 2/60 (3%)
 Frame = +1

Query: 319 HRDYPALLKYLQEKQVDPQFRRMLAWKAFQHVAS--YDSAVSEWLWKQSNSGDIFPPSFT 492
           H D   LL    EK+  P F+  L+ +   +  S  Y+ ++  W+ K+S     FPP FT
Sbjct: 55  HEDNQVLL----EKEGSPNFQDWLSKQPGVNKTSLKYNKSLGSWISKESKPKKRFPPYFT 110

---

>CUT1_SCHPO (P18296) Separin (EC 3.4.22.49) (Separase) (Cell untimely torn|
           protein 1)
          Length = 1828

 Score = 29.3 bits (64), Expect = 8.6
 Identities = 20/78 (25%), Positives = 40/78 (51%)
 Frame = +1

Query: 106 ARRDQEHHLKALNEHGIGTFDVVVVNLYPFYDKVTSGAISFEDGIENIDIGGPTLIRAAA 285
           A R +  +L     + +    VV  N    YD + SG +S  + + +++I  P  I    
Sbjct: 100 AHRPEVFYLLECCTYILEQMQVVTKNTSHLYDCIRSG-VSICNRLLDMEIFEPA-ISLLM 157

Query: 286 KNHKDVLVVVDHRDYPAL 339
           K HK++++++ +RD+ A+
Sbjct: 158 KTHKNLIILLTYRDHDAI 175

---

>VNS1_AHSV6 (P87505) Nonstructural protein NS1|
          Length = 548

 Score = 29.3 bits (64), Expect = 8.6
 Identities = 25/102 (24%), Positives = 45/102 (44%)
 Frame = +1

Query: 268 LIRAAAKNHKDVLVVVDHRDYPALLKYLQEKQVDPQFRRMLAWKAFQHVASYDSAVSEWL 447
           L+R AA++ K  +     R YP LL+  Q   ++     ++      H+  YD   S   
Sbjct: 236 LMRRAAQDFK-FITHAGWRLYPRLLR--QRFAIEDATEGVIHHVMLGHLRYYDEDTSIVK 292

Query: 448 WKQSNSGDIFPPSFTVPLSMKSTLRYGENPHQKAAFYGDRSL 573
           ++  N G +   ++T+PL +  T R G    +    +  +SL
Sbjct: 293 YRFLNDGSLDWRTWTIPLHLMRTARLGHLQPESILVFMHKSL 334


  Database: uniprot_sprot.fasta
    Posted date:  May 25, 2006  5:36 PM
  Number of letters in database: 80,573,946
  Number of sequences in database:  219,361
  
Lambda     K      H
   0.318    0.135    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 88,577,577
Number of Sequences: 219361
Number of extensions: 1891744
Number of successful extensions: 5920
Number of sequences better than 10.0: 109
Number of HSP's better than 10.0 without gapping: 5554
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5704
length of database: 80,573,946
effective HSP length: 106
effective length of database: 57,321,680
effective search space used: 4986986160
frameshift window, decay const: 50,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)

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