ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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| Clone Name | bags9h15 |
|---|---|
| Clone Library Name | barley_pub |
>ACSL1_MOUSE (P41216) Long-chain-fatty-acid--CoA ligase 1 (EC 6.2.1.3)| (Long-chain acyl-CoA synthetase 1) (LACS 1) Length = 699 Score = 144 bits (362), Expect = 3e-34 Identities = 75/182 (41%), Positives = 108/182 (59%), Gaps = 5/182 (2%) Frame = +1 Query: 100 YKWMTYGEAGTSRTAIGSGLICHGIPKGAR--VGLYFINRPEWTIVDNACSAYSYVSVPL 273 Y+W++Y E IGSGLI G + +GL+ NRPEW IV+ C +YS V VPL Sbjct: 119 YEWISYKEVAELAECIGSGLIQKGFKPCSEQFIGLFSQNRPEWVIVEQGCFSYSMVVVPL 178 Query: 274 YDTLGPDAVQFIVNHASVEAIFC-VPQTLSTLLSFITQM--PCVRLIVVVGGIDENMPSS 444 YDTLG DA+ +IVN A + IF P+ LL + PC+++IV++ ++ Sbjct: 179 YDTLGADAITYIVNKAELSVIFADKPEKAKLLLEGVENKLTPCLKIIVIMDSYGSDLVER 238 Query: 445 PAAAGMEIITYSMLHRQGHMSPQPFRPPKPEDVATICYTSGTTGTPKGAVLSHANFIANV 624 G+EII+ L G ++ +PP+PED+A IC+TSGTTG PKGA+++H N I + Sbjct: 239 GKKCGVEIISLKALEDLGRVNRVKPKPPEPEDLAIICFTSGTTGNPKGAMITHQNIINDC 298 Query: 625 AG 630 +G Sbjct: 299 SG 300
>ACSL1_RAT (P18163) Long-chain-fatty-acid--CoA ligase 1 (EC 6.2.1.3)| (Long-chain acyl-CoA synthetase 1) (LACS 1) (Long-chain-fatty-acid--CoA ligase, liver isozyme) Length = 699 Score = 137 bits (346), Expect = 2e-32 Identities = 70/182 (38%), Positives = 105/182 (57%), Gaps = 5/182 (2%) Frame = +1 Query: 100 YKWMTYGEAGTSRTAIGSGLICHGIPKGAR--VGLYFINRPEWTIVDNACSAYSYVSVPL 273 Y+W++Y + IGS LI G + +G++ NRPEW ++ C YS V VPL Sbjct: 119 YEWISYKQVAEMAECIGSALIQKGFKPCSEQFIGIFSQNRPEWVTIEQGCFTYSMVVVPL 178 Query: 274 YDTLGPDAVQFIVNHASVEAIFC-VPQTLSTLLSFITQM--PCVRLIVVVGGIDENMPSS 444 YDTLG DA+ +IVN A + IF P+ LL + PC+++IV++ D ++ Sbjct: 179 YDTLGTDAITYIVNKAELSVIFADKPEKAKLLLEGVENKLTPCLKIIVIMDSYDNDLVER 238 Query: 445 PAAAGMEIITYSMLHRQGHMSPQPFRPPKPEDVATICYTSGTTGTPKGAVLSHANFIANV 624 G+EII L G ++ +PP+PED+A IC+TSGTTG PKGA+++H N + + Sbjct: 239 GQKCGVEIIGLKALEDLGRVNRTKPKPPEPEDLAIICFTSGTTGNPKGAMVTHQNIMNDC 298 Query: 625 AG 630 +G Sbjct: 299 SG 300
>ACSL1_CAVPO (Q9JID6) Long-chain-fatty-acid--CoA ligase 1 (EC 6.2.1.3)| (Long-chain acyl-CoA synthetase 1) (LACS 1) (Palmitoyl-CoA ligase) Length = 698 Score = 132 bits (333), Expect = 6e-31 Identities = 67/179 (37%), Positives = 104/179 (58%), Gaps = 5/179 (2%) Frame = +1 Query: 100 YKWMTYGEAGTSRTAIGSGLICHGIPKGAR--VGLYFINRPEWTIVDNACSAYSYVSVPL 273 Y+W++Y + IGS L+ G +G++ NRPEW I++ AC AYS V VPL Sbjct: 118 YEWLSYKQVEDLSECIGSALLQKGFQASPDQFIGIFAQNRPEWVIIEQACFAYSMVVVPL 177 Query: 274 YDTLGPDAVQFIVNHASVEAIFC-VPQTLSTLLSFITQ--MPCVRLIVVVGGIDENMPSS 444 YDTLG DA+ +IVN A + IF P+ LL + P +++IVV+ + Sbjct: 178 YDTLGADAITYIVNKAELSVIFADKPEKARILLESVENKLTPGLKIIVVMDSYGSELVEQ 237 Query: 445 PAAAGMEIITYSMLHRQGHMSPQPFRPPKPEDVATICYTSGTTGTPKGAVLSHANFIAN 621 G+E+I+ + G + + +PP+P+D+A IC+TSGTTG PKGA+++H N +++ Sbjct: 238 GKKCGVEVISLKAMEGLGRANRRKPKPPEPDDLAVICFTSGTTGNPKGAMITHKNVVSD 296
>ACSL5_MOUSE (Q8JZR0) Long-chain-fatty-acid--CoA ligase 5 (EC 6.2.1.3)| (Long-chain acyl-CoA synthetase 5) (LACS 5) Length = 683 Score = 131 bits (329), Expect = 2e-30 Identities = 68/184 (36%), Positives = 111/184 (60%), Gaps = 8/184 (4%) Frame = +1 Query: 100 YKWMTYGEAGTSRTAIGSGLICHGIPKGAR--VGLYFINRPEWTIVDNACSAYSYVSVPL 273 YKW++Y + +GS L+ G VG++ NRPEW I + AC YS V+VPL Sbjct: 103 YKWISYKQVSDRAEYLGSCLLHKGYKSSQDQFVGIFAQNRPEWVISELACYTYSMVAVPL 162 Query: 274 YDTLGPDAVQFIVNHASVEAIFC-VPQTLSTLLSFITQ--MPCVRLIVVVGGIDENMPSS 444 YDTLG +A+ F++N A + + C PQ + L+ + + P ++ I+++ D+++ Sbjct: 163 YDTLGTEAIIFVINRADIPVVICDTPQKATMLVENVEKGLTPGLKTIILMDPFDDDLMKR 222 Query: 445 PAAAGMEIITYSMLHRQGHMSPQPFR---PPKPEDVATICYTSGTTGTPKGAVLSHANFI 615 G+E+++ LH ++ + F+ PPKPED++ IC+TSGTTG PKGA+L+H N + Sbjct: 223 GEKCGVEMLS---LHDAENIGKENFKKPVPPKPEDLSVICFTSGTTGDPKGAMLTHENVV 279 Query: 616 ANVA 627 +N+A Sbjct: 280 SNMA 283
>ACSL5_HUMAN (Q9ULC5) Long-chain-fatty-acid--CoA ligase 5 (EC 6.2.1.3)| (Long-chain acyl-CoA synthetase 5) (LACS 5) Length = 683 Score = 130 bits (327), Expect = 3e-30 Identities = 68/184 (36%), Positives = 110/184 (59%), Gaps = 8/184 (4%) Frame = +1 Query: 100 YKWMTYGEAGTSRTAIGSGLICHGIPKGAR--VGLYFINRPEWTIVDNACSAYSYVSVPL 273 Y+W++Y + +GS L+ G VG++ NRPEW I + AC YS V+VPL Sbjct: 103 YRWLSYKQVSDRAEYLGSCLLHKGYKSSPDQFVGIFAQNRPEWIISELACYTYSMVAVPL 162 Query: 274 YDTLGPDAVQFIVNHASVEAIFC-VPQTLSTLLSFITQ--MPCVRLIVVVGGIDENMPSS 444 YDTLGP+A+ IVN A + + C PQ L+ + + P +++I+++ D+++ Sbjct: 163 YDTLGPEAIVHIVNKADIAMVICDTPQKALVLIGNVEKGFTPSLKVIILMDPFDDDLKQR 222 Query: 445 PAAAGMEIITYSMLHRQGHMSPQPFR---PPKPEDVATICYTSGTTGTPKGAVLSHANFI 615 +G+EI++ L+ ++ + FR PP PED++ IC+TSGTTG PKGA+++H N + Sbjct: 223 GEKSGIEILS---LYDAENLGKEHFRKPVPPSPEDLSVICFTSGTTGDPKGAMITHQNIV 279 Query: 616 ANVA 627 +N A Sbjct: 280 SNAA 283
>ACSL6_HUMAN (Q9UKU0) Long-chain-fatty-acid--CoA ligase 6 (EC 6.2.1.3)| (Long-chain acyl-CoA synthetase 6) (LACS 6) Length = 697 Score = 130 bits (326), Expect = 4e-30 Identities = 67/182 (36%), Positives = 106/182 (58%), Gaps = 5/182 (2%) Frame = +1 Query: 100 YKWMTYGEAGTSRTAIGSGLICHGIPKGAR--VGLYFINRPEWTIVDNACSAYSYVSVPL 273 Y+W++Y E +GSGL+ H +G++ NRPEW IV+ AC YS V VPL Sbjct: 118 YQWLSYQEVADRAEFLGSGLLQHNCKACTDQFIGVFAQNRPEWIIVELACYTYSMVVVPL 177 Query: 274 YDTLGPDAVQFIVNHASVEAIFC-VPQTLSTLLSFI--TQMPCVRLIVVVGGIDENMPSS 444 YDTLGP A+++I+N A + + PQ LL + + P ++LI+++ +E + Sbjct: 178 YDTLGPGAIRYIINTADISTVIVDKPQKAVLLLEHVERKETPGLKLIILMDPFEEALKER 237 Query: 445 PAAAGMEIITYSMLHRQGHMSPQPFRPPKPEDVATICYTSGTTGTPKGAVLSHANFIANV 624 G+ I + + G + Q PP+P+D++ +C+TSGTTG PKGA+L+H N +A+ Sbjct: 238 GQKCGVVIKSMQAVEDCGQENHQAPVPPQPDDLSIVCFTSGTTGNPKGAMLTHGNVVADF 297 Query: 625 AG 630 +G Sbjct: 298 SG 299
>ACSL1_HUMAN (P33121) Long-chain-fatty-acid--CoA ligase 1 (EC 6.2.1.3)| (Long-chain acyl-CoA synthetase 1) (LACS 1) (Palmitoyl-CoA ligase 1) (Long-chain fatty acid CoA ligase 2) (Long-chain acyl-CoA synthetase 2) (LACS 2) (Acyl-CoA synthetase 1) (ACS1) (Pa Length = 698 Score = 128 bits (322), Expect = 1e-29 Identities = 65/179 (36%), Positives = 102/179 (56%), Gaps = 5/179 (2%) Frame = +1 Query: 100 YKWMTYGEAGTSRTAIGSGLICHGIPKGAR--VGLYFINRPEWTIVDNACSAYSYVSVPL 273 Y+W++Y + IGS LI G +G++ NRPEW I++ C AYS V VPL Sbjct: 118 YEWLSYKQVAELSECIGSALIQKGFKTAPDQFIGIFAQNRPEWVIIEQGCFAYSMVIVPL 177 Query: 274 YDTLGPDAVQFIVNHASVEAIFC-VPQTLSTLLSFITQ--MPCVRLIVVVGGIDENMPSS 444 YDTLG +A+ +IVN A + +F P+ LL + +P +++IVV+ + Sbjct: 178 YDTLGNEAITYIVNKAELSLVFVDKPEKAKLLLEGVENKLIPGLKIIVVMDAYGSELVER 237 Query: 445 PAAAGMEIITYSMLHRQGHMSPQPFRPPKPEDVATICYTSGTTGTPKGAVLSHANFIAN 621 G+E+ + + G + + +PP PED+A IC+TSGTTG PKGA+++H N +++ Sbjct: 238 GQRCGVEVTSMKAMEDLGRANRRKPKPPAPEDLAVICFTSGTTGNPKGAMVTHRNIVSD 296
>ACSL6_RAT (P33124) Long-chain-fatty-acid--CoA ligase 6 (EC 6.2.1.3)| (Long-chain acyl-CoA synthetase 6) (LACS 6) (Long-chain-fatty-acid--CoA ligase, brain isozyme) Length = 697 Score = 128 bits (322), Expect = 1e-29 Identities = 64/182 (35%), Positives = 106/182 (58%), Gaps = 5/182 (2%) Frame = +1 Query: 100 YKWMTYGEAGTSRTAIGSGLICHGIPKGAR--VGLYFINRPEWTIVDNACSAYSYVSVPL 273 Y+W++Y E +GSGL+ H G +G++ NRPEW I + AC YS V VPL Sbjct: 118 YQWLSYQEVAKRAEFLGSGLLQHDCKVGTEQFIGVFAQNRPEWIIAELACYTYSMVVVPL 177 Query: 274 YDTLGPDAVQFIVNHASV-EAIFCVPQTLSTLLSFIT--QMPCVRLIVVVGGIDENMPSS 444 YDTLGP ++++I+N A + I P LL + + P ++L++++ D+ + Sbjct: 178 YDTLGPGSIRYIINTADICTVIVDKPHKAILLLEHVERKETPGLKLVILMEPFDDALRER 237 Query: 445 PAAAGMEIITYSMLHRQGHMSPQPFRPPKPEDVATICYTSGTTGTPKGAVLSHANFIANV 624 G++I + + G + + PP+P+D++ +C+TSGTTG PKGA+L+H N +A+ Sbjct: 238 GKKCGVDIKSMQAIEDSGQENHRVPVPPRPDDLSIVCFTSGTTGNPKGAMLTHGNVVADF 297 Query: 625 AG 630 +G Sbjct: 298 SG 299
>ACSL5_RAT (O88813) Long-chain-fatty-acid--CoA ligase 5 (EC 6.2.1.3)| (Long-chain acyl-CoA synthetase 5) (LACS 5) Length = 683 Score = 128 bits (322), Expect = 1e-29 Identities = 64/184 (34%), Positives = 110/184 (59%), Gaps = 8/184 (4%) Frame = +1 Query: 100 YKWMTYGEAGTSRTAIGSGLICHGIPKGAR--VGLYFINRPEWTIVDNACSAYSYVSVPL 273 YKW++Y + +GS L+ G +G++ NRPEW I + AC YS V+VPL Sbjct: 103 YKWISYKQVSDRAEYLGSCLLHKGYKPSQDQFIGIFAQNRPEWVISELACYTYSMVAVPL 162 Query: 274 YDTLGPDAVQFIVNHASVEAIFC-VPQTLSTLLSFITQ--MPCVRLIVVVGGIDENMPSS 444 YDTLG +A+ +++N A + + C PQ + L+ + + P ++ ++++ D+++ Sbjct: 163 YDTLGAEAIIYVINRADISVVICDTPQKATMLIENVEKDLTPGLKTVILMDPFDDDLMKR 222 Query: 445 PAAAGMEIITYSMLHRQGHMSPQPFR---PPKPEDVATICYTSGTTGTPKGAVLSHANFI 615 G+E+++ LH ++ + F+ PP PED++ IC+TSGTTG PKGA+L+H N + Sbjct: 223 GEKCGIEMLS---LHDAENLGKENFKKPMPPNPEDLSVICFTSGTTGDPKGAMLTHQNIV 279 Query: 616 ANVA 627 +N+A Sbjct: 280 SNMA 283
>ACSL6_MOUSE (Q91WC3) Long-chain-fatty-acid--CoA ligase 6 (EC 6.2.1.3)| (Long-chain acyl-CoA synthetase 6) (LACS 6) Length = 697 Score = 127 bits (319), Expect = 3e-29 Identities = 66/185 (35%), Positives = 108/185 (58%), Gaps = 8/185 (4%) Frame = +1 Query: 100 YKWMTYGEAGTSRTAIGSGLICHGIPKGAR--VGLYFINRPEWTIVDNACSAYSYVSVPL 273 Y+W++Y E +GSGL+ H G VG++ NRPEW I + AC YS V VPL Sbjct: 118 YQWLSYQEVAKRAEFLGSGLLQHDCKVGTEQFVGVFAQNRPEWIIAELACYTYSMVVVPL 177 Query: 274 YDTLGPDAVQFIVNHASV-EAIFCVPQTLSTLLSFIT--QMPCVRLIVVVGGIDENMPSS 444 YDTLGP ++ +I+N A + I P + LL + + P ++L++++ ++ + Sbjct: 178 YDTLGPGSISYIINTADICTVIVDKPHKATLLLEHVERKETPGLKLVILMEPFEDALRER 237 Query: 445 PAAAGMEIITYSMLH---RQGHMSPQPFRPPKPEDVATICYTSGTTGTPKGAVLSHANFI 615 G++I + + R+ H +P P P+P+D++ +C+TSGTTG PKGA+L+H N + Sbjct: 238 GKKCGVDIKSMQAIEDCGRENHHAPVP---PRPDDLSIVCFTSGTTGNPKGAMLTHGNVV 294 Query: 616 ANVAG 630 A+ +G Sbjct: 295 ADFSG 299
>ACSL3_HUMAN (O95573) Long-chain-fatty-acid--CoA ligase 3 (EC 6.2.1.3)| (Long-chain acyl-CoA synthetase 3) (LACS 3) Length = 720 Score = 101 bits (251), Expect = 2e-21 Identities = 62/186 (33%), Positives = 87/186 (46%), Gaps = 6/186 (3%) Frame = +1 Query: 91 IGDYKWMTYGEAGTSRTAIGSGLICHGIPKGARVGLYFINRPEWTIVDNACSAYSYVSVP 270 +G Y W++Y + G+GL G + ++ R EW I AC Y++ V Sbjct: 129 LGQYNWLSYEDVFVRAFNFGNGLQMLGQKPKTNIAIFCETRAEWMIAAQACFMYNFQLVT 188 Query: 271 LYDTLGPDAVQFIVNHASVEAIFCVPQTLSTLLSFITQM-PCVRLIVVVGGIDENMPSSP 447 LY TLG A+ +N V I + L T L I + P +R I+ V G P Sbjct: 189 LYATLGGPAIVHALNETEVTNIITSKELLQTKLKDIVSLVPRLRHIITVDGKPPTWSDFP 248 Query: 448 AAAGMEIITYSM-----LHRQGHMSPQPFRPPKPEDVATICYTSGTTGTPKGAVLSHANF 612 II ++M L + M QP P P D+A I YTSG+TG PKG ++SH+N Sbjct: 249 KG----IIVHTMAAVEALGAKASMENQPHSKPLPSDIAVIMYTSGSTGLPKGVMISHSNI 304 Query: 613 IANVAG 630 IA + G Sbjct: 305 IAGITG 310
>ACSL3_MOUSE (Q9CZW4) Long-chain-fatty-acid--CoA ligase 3 (EC 6.2.1.3)| (Long-chain acyl-CoA synthetase 3) (LACS 3) Length = 720 Score = 95.9 bits (237), Expect = 9e-20 Identities = 58/184 (31%), Positives = 90/184 (48%), Gaps = 4/184 (2%) Frame = +1 Query: 91 IGDYKWMTYGEAGTSRTAIGSGLICHGIPKGARVGLYFINRPEWTIVDNACSAYSYVSVP 270 +G Y W++Y + G+GL G A + ++ R EW I AC Y++ V Sbjct: 129 LGHYNWLSYEDVFIRALDFGNGLQMLGQKPKANIAIFCETRAEWMIAAQACFMYNFQLVT 188 Query: 271 LYDTLGPDAVQFIVNHASVEAIFCVPQTLST-LLSFITQMPCVRLIVVVGGIDENMPSSP 447 LY TLG A+ +N V I + L T L ++ +P +R I+ V G P Sbjct: 189 LYATLGGPAIVHGLNETEVTNIITSKELLQTKLKEIVSLVPRLRHIITVDGKPPTWSEFP 248 Query: 448 AAAGMEIITYSMLHRQG---HMSPQPFRPPKPEDVATICYTSGTTGTPKGAVLSHANFIA 618 G+ + T + + G ++ + P P D+A I YTSG+TG PKG ++SH+N IA Sbjct: 249 --KGVIVHTMAAVQALGVKANVEKKAHSKPLPSDIAVIMYTSGSTGIPKGVMISHSNIIA 306 Query: 619 NVAG 630 ++ G Sbjct: 307 SITG 310
>ACSL4_MOUSE (Q9QUJ7) Long-chain-fatty-acid--CoA ligase 4 (EC 6.2.1.3)| (Long-chain acyl-CoA synthetase 4) (LACS 4) (mACS4) Length = 711 Score = 95.9 bits (237), Expect = 9e-20 Identities = 60/185 (32%), Positives = 90/185 (48%), Gaps = 5/185 (2%) Frame = +1 Query: 91 IGDYKWMTYGEAGTSRTAIGSGLICHGIPKGARVGLYFINRPEWTIVDNACSAYSYVSVP 270 +G+YKW+ Y E GSGL G+ + ++ R EW I C Y++ V Sbjct: 120 LGNYKWINYLEVNCRVNNFGSGLTALGLKPKNTIAIFCETRAEWMIAAQTCFKYNFPLVT 179 Query: 271 LYDTLGPDAVQFIVNHASVEAIFCVPQTL-STLLSFITQMPCVRLIVVVGGIDENMPSSP 447 LY TLG +AV +N + + + L S L + + + CV+ I+ V N P Sbjct: 180 LYATLGREAVVHGLNESEASYLITSVELLESKLKAALVDINCVKHIIYVDNKTINRAEYP 239 Query: 448 AAAGMEIITYSMLHRQG----HMSPQPFRPPKPEDVATICYTSGTTGTPKGAVLSHANFI 615 G+EI + + G ++S P R P P D+A + YTSG+TG PKG ++ H N I Sbjct: 240 --EGLEIHSMQSVEELGAKPENLSVPPSR-PTPSDMAIVMYTSGSTGRPKGLMMHHTNLI 296 Query: 616 ANVAG 630 A + G Sbjct: 297 AGMTG 301
>ACSL4_HUMAN (O60488) Long-chain-fatty-acid--CoA ligase 4 (EC 6.2.1.3)| (Long-chain acyl-CoA synthetase 4) (LACS 4) Length = 711 Score = 95.5 bits (236), Expect = 1e-19 Identities = 60/185 (32%), Positives = 89/185 (48%), Gaps = 5/185 (2%) Frame = +1 Query: 91 IGDYKWMTYGEAGTSRTAIGSGLICHGIPKGARVGLYFINRPEWTIVDNACSAYSYVSVP 270 +G+YKWM Y E GSGL G+ + ++ R EW I C Y++ V Sbjct: 120 LGNYKWMNYLEVNRRVNNFGSGLTALGLKPKNTIAIFCETRAEWMIAAQTCFKYNFPLVT 179 Query: 271 LYDTLGPDAVQFIVNHASVEAIFCVPQTL-STLLSFITQMPCVRLIVVVGGIDENMPSSP 447 LY TLG +AV +N + + + L S L + + + CV+ I+ V N P Sbjct: 180 LYATLGKEAVVHGLNESEASYLITSVELLESKLKTALLDISCVKHIIYVDNKAINKAEYP 239 Query: 448 AAAGMEIITYSMLHRQGHMSPQ----PFRPPKPEDVATICYTSGTTGTPKGAVLSHANFI 615 G EI + + G +P+ P P P D+A + YTSG+TG PKG ++ H+N I Sbjct: 240 --EGFEIHSMQSVEELG-SNPENLGIPPSRPTPSDMAIVMYTSGSTGRPKGVMMHHSNLI 296 Query: 616 ANVAG 630 A + G Sbjct: 297 AGMTG 301
>ACSL4_RAT (O35547) Long-chain-fatty-acid--CoA ligase 4 (EC 6.2.1.3)| (Long-chain acyl-CoA synthetase 4) (LACS 4) Length = 670 Score = 95.5 bits (236), Expect = 1e-19 Identities = 59/184 (32%), Positives = 88/184 (47%), Gaps = 4/184 (2%) Frame = +1 Query: 91 IGDYKWMTYGEAGTSRTAIGSGLICHGIPKGARVGLYFINRPEWTIVDNACSAYSYVSVP 270 +G+YKW+ Y E GSGL G+ + ++ R EW I C Y++ V Sbjct: 79 LGNYKWINYLEVNCRVNNFGSGLTALGLKPKNTIAIFCETRAEWMIAAQTCFKYNFPLVT 138 Query: 271 LYDTLGPDAVQFIVNHASVEAIFCVPQTL-STLLSFITQMPCVRLIVVVGGIDENMPSSP 447 LY TLG +AV +N + + + L S L + + + CV+ I+ V N P Sbjct: 139 LYATLGKEAVVHGLNESEASYLITSVELLESKLKAALLDINCVKHIIYVDNKTINRAEYP 198 Query: 448 AAAGMEIITYSMLHRQG---HMSPQPFRPPKPEDVATICYTSGTTGTPKGAVLSHANFIA 618 G+EI + + G S P P P D+A + YTSG+TG PKG ++ H+N IA Sbjct: 199 --EGLEIHSMQSVEELGSKPENSSIPPSRPTPSDMAIVMYTSGSTGRPKGVMMHHSNLIA 256 Query: 619 NVAG 630 + G Sbjct: 257 GMTG 260
>ACSL3_RAT (Q63151) Long-chain-fatty-acid--CoA ligase 3 (EC 6.2.1.3)| (Long-chain acyl-CoA synthetase 3) (LACS 3) (Brain acyl-CoA synthtase II) Length = 720 Score = 95.1 bits (235), Expect = 1e-19 Identities = 58/184 (31%), Positives = 89/184 (48%), Gaps = 4/184 (2%) Frame = +1 Query: 91 IGDYKWMTYGEAGTSRTAIGSGLICHGIPKGARVGLYFINRPEWTIVDNACSAYSYVSVP 270 +G Y W++Y + G+GL G A + ++ R EW I AC Y++ V Sbjct: 129 LGHYNWLSYEDVFIRALDFGNGLQMLGQKPKANIAIFCETRAEWMIAAQACFMYNFQLVT 188 Query: 271 LYDTLGPDAVQFIVNHASVEAIFCVPQTLST-LLSFITQMPCVRLIVVVGGIDENMPSSP 447 LY TLG A+ +N V I + L T L ++ +P +R I+ V G P Sbjct: 189 LYATLGGPAIVHGLNETEVTNIITSKELLQTKLKDIVSLVPRLRHIITVDGKPPTWSEFP 248 Query: 448 AAAGMEIITYSMLHRQG---HMSPQPFRPPKPEDVATICYTSGTTGTPKGAVLSHANFIA 618 G+ + T + + G + + P P D+A I YTSG+TG PKG ++SH+N IA Sbjct: 249 --KGVIVHTMAAVQALGVKADVDKKAHSKPLPSDIAVIMYTSGSTGIPKGVMISHSNIIA 306 Query: 619 NVAG 630 ++ G Sbjct: 307 SITG 310
>LCF2_YEAST (P39518) Long-chain-fatty-acid--CoA ligase 2 (EC 6.2.1.3)| (Long-chain acyl-CoA synthetase 2) (Fatty acid activator 2) Length = 744 Score = 84.0 bits (206), Expect = 3e-16 Identities = 53/195 (27%), Positives = 89/195 (45%), Gaps = 19/195 (9%) Frame = +1 Query: 100 YKWMTYGEAGTSRTAIGSGLICHGIPKGAR--------VGLYFINRPEWTIVDNACSAYS 255 +++ +Y IGSG++ K R V + N PEW + D AC AYS Sbjct: 128 FRFESYSTVSKRCHNIGSGILSLVNTKRKRPLEANDFVVAILSHNNPEWILTDLACQAYS 187 Query: 256 YVSVPLYDTLGPDAVQFIVNHASVEAIFCVPQTLSTLLSFITQMPCVRLIVVVGGIDEN- 432 + LY+TLGP+ ++I+N + + +L + M V +V + + + Sbjct: 188 LTNTALYETLGPNTSEYILNLTEAPILIFAKSNMYHVLKMVPDMKFVNTLVCMDELTHDE 247 Query: 433 --------MPSSPAAAGMEIITYSM--LHRQGHMSPQPFRPPKPEDVATICYTSGTTGTP 582 +P + +I +S+ + + G + P PP P+ + TI +TSGTTG P Sbjct: 248 LRMLNESLLPVKCNSLNEKITFFSLEQVEQVGCFNKIPAIPPTPDSLYTISFTSGTTGLP 307 Query: 583 KGAVLSHANFIANVA 627 KG +SH N + +A Sbjct: 308 KGVEMSHRNIASGIA 322
>LCF1_SCHPO (O60135) Long-chain-fatty-acid--CoA ligase 1 (EC 6.2.1.3)| (Long-chain acyl-CoA synthetase 1) (Fatty acid activator 1) Length = 676 Score = 77.4 bits (189), Expect = 3e-14 Identities = 46/180 (25%), Positives = 81/180 (45%), Gaps = 2/180 (1%) Frame = +1 Query: 91 IGDYKWMTYGEAGTSRTAIGSGLICHGIPKGARVGLYFINRPEWTIVDNACSAYSYVSVP 270 + DY ++++ + L G+ KG + LY W + AC + S V Sbjct: 91 LSDYNYLSFNDIYDKALRYAGALRKLGLNKGDKFELYAPTSAFWLLTAEACLSQSMTIVT 150 Query: 271 LYDTLGPDAVQFIVNHASVEAIFCVPQTLSTLLSFITQMPCVRLIVVVGGIDEN--MPSS 444 YDTLG + + + + V ++ L TL++ + ++ + +I+ E Sbjct: 151 AYDTLGEEGLLHSLRESGVRGMYTEGHLLKTLVNPLKEIESLEVIIYRNDAKEEDIKTIQ 210 Query: 445 PAAAGMEIITYSMLHRQGHMSPQPFRPPKPEDVATICYTSGTTGTPKGAVLSHANFIANV 624 +++I ++ + P PP PE++ I YTSG+TG PKG +LSH N +A V Sbjct: 211 EIRPNLKLIKFADFEKMS--PPVEPDPPSPEEICCIMYTSGSTGLPKGVILSHKNMVAIV 268
>LCFH_HAEIN (P44446) Putative long-chain-fatty-acid--CoA ligase (EC 6.2.1.3)| (Long-chain acyl-CoA synthetase) (LACS) Length = 607 Score = 72.0 bits (175), Expect = 1e-12 Identities = 51/181 (28%), Positives = 77/181 (42%), Gaps = 1/181 (0%) Frame = +1 Query: 70 RVHADGTIGDYKWMTYGEAGTSRTAIGSGLICHGIPKGARVGLYFINRPEWTIVDNACSA 249 R G D W + E + L+ H I ++ ++ N WTIVD A Sbjct: 33 RYKEHGLWRDISWKNFQE---QLNQLSRALLAHNIDVQDKIAIFAHNMERWTIVDIATLQ 89 Query: 250 YSYVSVPLYDTLGPDAVQFIVNHASVEAIFCVPQ-TLSTLLSFITQMPCVRLIVVVGGID 426 ++VP+Y T +FI+NHA V+ +F Q L P ++ IV + Sbjct: 90 IRAITVPIYATNTAQQAEFILNHADVKILFVGDQEQYDQTLEIAHHCPKLQKIVAMKSTI 149 Query: 427 ENMPSSPAAAGMEIITYSMLHRQGHMSPQPFRPPKPEDVATICYTSGTTGTPKGAVLSHA 606 + + P + E + + Q Q + D+ TI YTSGTTG PKG +L +A Sbjct: 150 Q-LQQDPLSCTWESFIKTGSNAQQDELTQRLNQKQLSDLFTIIYTSGTTGEPKGVMLDYA 208 Query: 607 N 609 N Sbjct: 209 N 209
>LCF4_YEAST (P47912) Long-chain-fatty-acid--CoA ligase 4 (EC 6.2.1.3)| (Long-chain acyl-CoA synthetase 4) (Fatty acid activator 4) Length = 694 Score = 62.8 bits (151), Expect = 8e-10 Identities = 59/200 (29%), Positives = 81/200 (40%), Gaps = 23/200 (11%) Frame = +1 Query: 100 YKWMTYGEAGTSRTAIGSGLICHGI-PKGA-RVGLYFINRPEWTIVDNACSAYSYVSVPL 273 Y MTY E IG GLI G+ P G + ++ +W C + V Sbjct: 97 YITMTYEEMICVMHDIGRGLIKIGVKPNGENKFHIFASTSHKWMKTFLGCMSQGIPVVTA 156 Query: 274 YDTLGPDAVQFIVNHASVEAIFCVPQTLSTLLSFITQMPCVRLIVVVGGIDENMPSSPAA 453 YDTLG + + AIF Q LS L + V+ ++ ID PS Sbjct: 157 YDTLGESGLIHSMVETDSVAIFTDNQLLSKLAVPLKTAKNVKFVIHNEPID---PSDKRQ 213 Query: 454 AG-------------------MEIITYSMLHRQGHMSPQPFRP--PKPEDVATICYTSGT 570 G ++I ++ + G + PKPED A I YTSG+ Sbjct: 214 NGKLYKAAKDAVDKIKEVRPDIKIYSFDEIIEIGKKAKDEVELHFPKPEDPACIMYTSGS 273 Query: 571 TGTPKGAVLSHANFIANVAG 630 TGTPKG VL+H N +A + G Sbjct: 274 TGTPKGVVLTHYNIVAGIGG 293
>LCF3_YEAST (P39002) Long-chain-fatty-acid--CoA ligase 3 (EC 6.2.1.3)| (Long-chain acyl-CoA synthetase 3) (Fatty acid activator 3) Length = 694 Score = 61.2 bits (147), Expect = 2e-09 Identities = 51/197 (25%), Positives = 83/197 (42%), Gaps = 20/197 (10%) Frame = +1 Query: 100 YKWMTYGEAGTSRTAIGSGLICHGI-PKGA-RVGLYFINRPEWTIVDNACSAYSYVSVPL 273 YK MTY E +G GL GI P G + ++ +W + C + V Sbjct: 97 YKMMTYQELIWVMHDMGRGLAKIGIKPNGEHKFHIFASTSHKWMKIFLGCISQGIPVVTA 156 Query: 274 YDTLGPDAVQFIVNHASVEAIFCVPQTLSTLLSFITQMPCVRLIVVVGGIDENMPSS--- 444 YDTLG + + AIF Q L+ ++ + ++ ++ ID N Sbjct: 157 YDTLGESGLIHSMVETESAAIFTDNQLLAKMIVPLQSAKDIKFLIHNEPIDPNDRRQNGK 216 Query: 445 -------------PAAAGMEIITYSMLHRQGHMSPQPFR--PPKPEDVATICYTSGTTGT 579 ++I ++ + + G S + PP+P+D+A I YTSG+ Sbjct: 217 LYKAAKDAINKIREVRPDIKIYSFEEVVKIGKKSKDEVKLHPPEPKDLACIMYTSGSISA 276 Query: 580 PKGAVLSHANFIANVAG 630 PKG VL+H N ++ +AG Sbjct: 277 PKGVVLTHYNIVSGIAG 293
>FADK_ECOLI (P38135) Short-chain-fatty-acid--CoA ligase (EC 6.2.1.-) (Acyl-CoA| synthetase) Length = 548 Score = 56.6 bits (135), Expect = 6e-08 Identities = 41/175 (23%), Positives = 80/175 (45%), Gaps = 5/175 (2%) Frame = +1 Query: 112 TYGEAGTSRTAIGSGLICHGIPKGARVGLYFINRPEWTIVDNACSAYSYVSVPLYDTLGP 291 TY + + + + ++ GI G R+ E+T++ AC VSVPL + Sbjct: 52 TYSALDHAASCLANWMLAKGIESGDRIAFQLPGWCEFTVIYLACLKIGAVSVPLLPSWRE 111 Query: 292 DAVQFIVNHASVEAIFCVP-----QTLSTLLSFITQMPCVRLIVVVGGIDENMPSSPAAA 456 + +++N + F + + +L Q+P ++ IV G+D+ P++ + + Sbjct: 112 AELVWVLNKCQAKMFFAPTLFKQTRPVDLILPLQNQLPQLQQIV---GVDKLAPATSSLS 168 Query: 457 GMEIITYSMLHRQGHMSPQPFRPPKPEDVATICYTSGTTGTPKGAVLSHANFIAN 621 +II + S +++A + +TSGT G PKG +L+H N +A+ Sbjct: 169 LSQIIA-------DNTSLTTAITTHGDELAAVLFTSGTEGLPKGVMLTHNNILAS 216
>ACSA_RHOCA (O68040) Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA| ligase) (Acyl-activating enzyme) Length = 656 Score = 52.0 bits (123), Expect = 1e-06 Identities = 47/184 (25%), Positives = 76/184 (41%), Gaps = 11/184 (5%) Frame = +1 Query: 109 MTYGEAGTSRTAIGSGLICHGIPKGARVGLYFINRPEWTIVDNACSAYSYVSVPLYDTLG 288 +TY E + + L+ GI +G RV +Y PE AC+ + ++ Sbjct: 115 ITYKELSEKVNRMANVLLSQGIMRGDRVVIYLPMIPEAAYAMLACARIGAIHSIVFAGFS 174 Query: 289 PDAVQFIVNHASVEAIFCV----------PQTLSTLLSFITQMPCVRLIVVVGGIDENMP 438 PDA+ +N + + P +T + + VR +VV D+ Sbjct: 175 PDALANRINDCGAKLVITADTAPRGGRRTPLKANTDAALLHCSDKVRCLVVKHTGDQ--- 231 Query: 439 SSPAAAGMEIITYSMLHRQGHMSPQ-PFRPPKPEDVATICYTSGTTGTPKGAVLSHANFI 615 G ++ +L+ H+SP+ P RP ED I YTSG+TG PKG V + ++ Sbjct: 232 -ISWVHGRDV---DLLYLMEHVSPECPPRPMNAEDPLFILYTSGSTGKPKGVVHTTGGYL 287 Query: 616 ANVA 627 A Sbjct: 288 VYAA 291
>LCF1_YEAST (P30624) Long-chain-fatty-acid--CoA ligase 1 (EC 6.2.1.3)| (Long-chain acyl-CoA synthetase 1) (Fatty acid activator 1) Length = 700 Score = 51.2 bits (121), Expect = 2e-06 Identities = 50/200 (25%), Positives = 80/200 (40%), Gaps = 20/200 (10%) Frame = +1 Query: 91 IGDYKWMTYGEAGTSRTAIGSGLICHGIPKGA--RVGLYFINRPEWTIVDNACSAYSYVS 264 + Y + ++ + IG GL+ G+ ++ LY +W + + Sbjct: 94 LSHYHYNSFDQLTDIMHEIGRGLVKIGLKPNDDDKLHLYAATSHKWMKMFLGAQSQGIPV 153 Query: 265 VPLYDTLGPDAVQFIVNHASVEAIFCVPQTLSTLLSFITQMPCVRLIVVVGGIDEN---- 432 V YDTLG + + +AIF L +L+ + V+ I+ I Sbjct: 154 VTAYDTLGEKGLIHSLVQTGSKAIFTDNSLLPSLIKPVQAAQDVKYIIHFDSISSEDRRQ 213 Query: 433 ----MPSSPAAAGM------EIITYSM--LHRQGHMSPQPF--RPPKPEDVATICYTSGT 570 S+ A +I T+S + + G S PP +D+ I YTSG+ Sbjct: 214 SGKIYQSAHDAINRIKEVRPDIKTFSFDDILKLGKESCNEIDVHPPGKDDLCCIMYTSGS 273 Query: 571 TGTPKGAVLSHANFIANVAG 630 TG PKG VL H+N +A V G Sbjct: 274 TGEPKGVVLKHSNVVAGVGG 293
>ACSA_RHOBA (P59872) Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA| ligase) (Acyl-activating enzyme) Length = 671 Score = 48.1 bits (113), Expect = 2e-05 Identities = 44/187 (23%), Positives = 77/187 (41%), Gaps = 10/187 (5%) Frame = +1 Query: 82 DGTIGDYKWMTYGEAGTSRTAIGSGLICHGIPKGARVGLYFINRPEWTIVDNACSAYSYV 261 DG D + +TY E T GL GI G V +Y PE + AC+ + Sbjct: 129 DGQPRDQRTLTYAELQTEVAKCAEGLTQLGIGVGDVVSIYMPMTPELAVAMLACARIGAI 188 Query: 262 SVPLYDTLGPDAVQFIVNHASVEAIFC---------VPQTLSTLLSFITQMPCVRLIVVV 414 ++ +++ N AS + + V +T+ + + P V +V+ Sbjct: 189 HSVIFAGFSAESIAERNNDASAKLVITSDGLYRRGKVLPLKATVDEALEKSPTVEKCLVL 248 Query: 415 GGIDENMPSSPAAAGMEIITYSMLHRQ-GHMSPQPFRPPKPEDVATICYTSGTTGTPKGA 591 ++ +P G ++ + ++ Q G M+ +P P I YTSG+TG PKG Sbjct: 249 RRTGDD---APMQEGRDVWWHDVVENQPGEMAAKPLDSETP---LFILYTSGSTGKPKGI 302 Query: 592 VLSHANF 612 + + A + Sbjct: 303 LHTTAGY 309
>ACSA_PENCH (P36333) Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA| ligase) (Acyl-activating enzyme) Length = 669 Score = 47.8 bits (112), Expect = 3e-05 Identities = 46/183 (25%), Positives = 78/183 (42%), Gaps = 10/183 (5%) Frame = +1 Query: 109 MTYGEAGTSRTAIGSGLICHGIPKGARVGLYFINRPEWTIVDNACSAYSYVSVPLYDTLG 288 +TYGE + + L G+ KG VG+Y PE I ACS V ++ Sbjct: 128 ITYGELMREVSRVAWTLKERGVKKGDTVGIYLPMIPEAVIAFLACSRIGAVHSVVFAGFS 187 Query: 289 PDAVQFIVNHASVEAIFCVPQ---------TLSTLLSFITQMPCVRLIVVVGGIDENMPS 441 D+++ V AS + I + T + + Q P V ++V +P Sbjct: 188 SDSLRDRVLDASSKVIITSDEGKRGGKIIGTKKIVDEAMKQCPDVHTVLVYKRTGAEVPW 247 Query: 442 SPAAAGMEIITYSMLHR-QGHMSPQPFRPPKPEDVATICYTSGTTGTPKGAVLSHANFIA 618 + AG +I + + + +++P+ ED + YTSG+TG PKG + + A ++ Sbjct: 248 T---AGRDIWWHEEVEKYPNYLAPESV---SSEDPLFLLYTSGSTGKPKGVMHTTAGYLL 301 Query: 619 NVA 627 A Sbjct: 302 GAA 304
>FAT2_SCHPO (O74976) Putative peroxisomal-coenzyme A synthetase (EC 6.-.-.-)| Length = 512 Score = 47.8 bits (112), Expect = 3e-05 Identities = 35/131 (26%), Positives = 60/131 (45%), Gaps = 19/131 (14%) Frame = +1 Query: 289 PDAVQFIVNHASV--EAIFCVPQTLSTLLS----FITQMPCVRLIVVVGGIDENMPSSPA 450 P+ ++F+V +V + C P + S +I + +IV G + N P+ A Sbjct: 60 PNGLEFVVAFYAVSWQRAICGPLNSNYKQSEFEFYIDDLKSKLVIVPEGSVAANTPAVRA 119 Query: 451 AAGMEIITYSM-----------LHRQGHM--SPQPFRPPKPEDVATICYTSGTTGTPKGA 591 A + + + +H +G +PQP P+P+DV + +TSGTTG PK Sbjct: 120 AKKLSVAVAELAWCPKSRLVRIVHFEGAKINAPQPLGLPQPDDVMLVLHTSGTTGRPKVV 179 Query: 592 VLSHANFIANV 624 L+H N ++ Sbjct: 180 PLTHKNLCRSI 190
>ACS2L_MOUSE (Q99NB1) Acetyl-coenzyme A synthetase 2-like, mitochondrial| precursor (EC 6.2.1.1) (Acetate--CoA ligase 2) (Acetyl-CoA synthetase 2) (AceCS2) (Acyl-CoA synthetase short-chain family member 1) Length = 682 Score = 47.4 bits (111), Expect = 4e-05 Identities = 41/182 (22%), Positives = 73/182 (40%), Gaps = 9/182 (4%) Frame = +1 Query: 109 MTYGEAGTSRTAIGSGLICHGIPKGARVGLYFINRPEWTIVDNACSAYSYVSVPLYDTLG 288 +TY E + + + L HG+ +G RV +Y P AC+ + ++ Sbjct: 134 ITYRELLETTCRLANTLKRHGVHRGDRVAIYMPVSPLAVAAMLACARIGAIHTVVFAGFS 193 Query: 289 PDAVQFIVNHASVEAIFCVPQTL---------STLLSFITQMPCVRLIVVVGGIDENMPS 441 +++ +N A +A+ Q L + + P V+ ++V D +P Sbjct: 194 AESLAGRINDAKCKAVITFNQGLRGGRVVELKKIVDEAVKSCPTVQHVLVAHRTDTKVPM 253 Query: 442 SPAAAGMEIITYSMLHRQGHMSPQPFRPPKPEDVATICYTSGTTGTPKGAVLSHANFIAN 621 +E M +P+ ED+ + YTSG+TGTPKG V + A ++ Sbjct: 254 GSLDIPLE---QEMAKEAPVCTPESM---SSEDMLFMLYTSGSTGTPKGLVHTQAGYLLY 307 Query: 622 VA 627 A Sbjct: 308 AA 309
>ACSA_CAMJE (Q9PMD2) Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA| ligase) (Acyl-activating enzyme) Length = 657 Score = 47.0 bits (110), Expect = 5e-05 Identities = 43/186 (23%), Positives = 74/186 (39%), Gaps = 8/186 (4%) Frame = +1 Query: 82 DGTIGDYKWMTYGEAGTSRTAIGSGLICHGIPKGARVGLYFINRPEWTIVDNACSAYSYV 261 +G +GDY+ TY + L G+ KG RV +Y PE IV AC+ + Sbjct: 100 EGEMGDYEVYTYRRLLHETCKAANLLKKFGVKKGDRVVIYMPMIPETAIVMLACARIGAI 159 Query: 262 SVPLYDTLGPDAVQFIVNHASVEAIFCV--------PQTLSTLLSFITQMPCVRLIVVVG 417 ++ P+A++ + A + + P L + C + V+ Sbjct: 160 HSVVFGGFSPEALRDRIIDAGAKLVVTADGAFRRGKPYMLKPAVDKALSEGCESVEKVLI 219 Query: 418 GIDENMPSSPAAAGMEIITYSMLHRQGHMSPQPFRPPKPEDVATICYTSGTTGTPKGAVL 597 I N P G + + ++ + + ED+ + YTSG+TG PKG + Sbjct: 220 VIRNNEPIE-YIKGRDYVYNELVKNESYKCEPEIMDS--EDLLFLLYTSGSTGKPKGVMH 276 Query: 598 SHANFI 615 + A +I Sbjct: 277 ASAGYI 282
>ACSA_BACSU (P39062) Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA| ligase) (Acyl-activating enzyme) (Acetyl-CoA synthase) Length = 572 Score = 46.6 bits (109), Expect = 6e-05 Identities = 41/169 (24%), Positives = 73/169 (43%), Gaps = 1/169 (0%) Frame = +1 Query: 112 TYGEAGTSRTAIGSGLICHG-IPKGARVGLYFINRPEWTIVDNACSAYSYVSVPLYDTLG 288 T+ E G+ L +G + KG RV ++ PE + ++ PL++ Sbjct: 75 TFKEMKEESNRAGNVLRRYGNVEKGDRVFIFMPRSPELYFIMLGAIKIGAIAGPLFEAFM 134 Query: 289 PDAVQFIVNHASVEAIFCVPQTLSTLLSFITQMPCVRLIVVVGGIDENMPSSPAAAGMEI 468 AV+ + ++ + + P+ L + + ++P ++ + VVGG A +G I Sbjct: 135 EGAVKDRLENSEAKVVVTTPELLERIP--VDKLPHLQHVFVVGG--------EAESGTNI 184 Query: 469 ITYSMLHRQGHMSPQPFRPPKPEDVATICYTSGTTGTPKGAVLSHANFI 615 I Y +Q + +D + YTSG+TGTPKG + H I Sbjct: 185 INYDEAAKQ-ESTRLDIEWMDKKDGFLLHYTSGSTGTPKGVLHVHEAMI 232
>ACSA_STRAW (Q82EL5) Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA| ligase) (Acyl-activating enzyme) Length = 652 Score = 46.2 bits (108), Expect = 8e-05 Identities = 42/195 (21%), Positives = 79/195 (40%), Gaps = 10/195 (5%) Frame = +1 Query: 73 VHADGTIGDYKWMTYGEAGTSRTAIGSGLICHGIPKGARVGLYFINRPEWTIVDNACSAY 252 +H +G GD + +TY E + + L G+ KG RV +Y PE + AC+ Sbjct: 98 IHFEGEPGDSRAITYAELKDEVSKAANALTELGVQKGDRVAVYLPMIPEAVVAMLACARI 157 Query: 253 SYVSVPLYDTLGPDAVQFIVNHASVEAIFCV--------PQTLSTLL-SFITQMPCVRLI 405 ++ DA+ + A + + P L + +++ V + Sbjct: 158 GAAHSVVFGGFSADAIAARIKDADAKLVITADGGYRRGKPSALKPAVDDAVSRGDGVEKV 217 Query: 406 VVVGGIDENMPSSPAAAGMEIITYSMLHRQ-GHMSPQPFRPPKPEDVATICYTSGTTGTP 582 +VV + + + G ++ + + +Q +P+ F P I YTSGTTG P Sbjct: 218 LVVRRTGQEVAWT---EGRDVWWHEITAKQSAEHTPEAFDAEHP---LFILYTSGTTGKP 271 Query: 583 KGAVLSHANFIANVA 627 KG + + ++ + Sbjct: 272 KGILHTSGGYLTQTS 286
>FAD11_MYCTU (Q10776) Putative fatty-acid--CoA ligase fadD11 (EC 6.2.1.-)| (Acyl-CoA synthetase) Length = 571 Score = 46.2 bits (108), Expect = 8e-05 Identities = 18/33 (54%), Positives = 25/33 (75%) Frame = +1 Query: 517 FRPPKPEDVATICYTSGTTGTPKGAVLSHANFI 615 +R +PED+ T+ YTSGTTG PKG ++HAN + Sbjct: 125 WRAVQPEDIVTLIYTSGTTGNPKGVEMTHANLL 157
>ACSA2_PSEPK (Q88DW6) Acetyl-coenzyme A synthetase 2 (EC 6.2.1.1) (Acetate--CoA| ligase 2) (Acyl-activating enzyme 2) Length = 644 Score = 46.2 bits (108), Expect = 8e-05 Identities = 39/187 (20%), Positives = 74/187 (39%), Gaps = 14/187 (7%) Frame = +1 Query: 97 DYKWMTYGEAGTSRTAIGSGLICHGIPKGARVGLYFINRPEWTIVDNACSAYSYVSVPLY 276 D K +TY E + + + G+ KG RV +Y PE AC+ + ++ Sbjct: 102 DSKAITYRELHRQVCRLANAMKARGVKKGDRVSIYMPMIPEAAFAMLACTRIGAIHSVVF 161 Query: 277 DTLGPDAVQFIVNHASVEAIFCVPQTLSTLLSFITQMPCVRLIVVVGGIDENMPSSPAAA 456 PDA++ + A + + + + I + +D+ + S PA + Sbjct: 162 GGFSPDALRDRILDADCRTVITADEGVRG----------GKRIPLKQNVDKALASCPAVS 211 Query: 457 GMEIITYS-----------MLHRQGHMSPQPFRPPKP---EDVATICYTSGTTGTPKGAV 594 + ++ + + + + PP+P ED I YTSG+TG PKG + Sbjct: 212 SVLVVRRTGGDVAWTEGRDLWYHEATKDAGDDCPPEPMEAEDPLFILYTSGSTGKPKGVL 271 Query: 595 LSHANFI 615 + ++ Sbjct: 272 HTTGGYL 278
>LCFA_BACSU (P94547) Long-chain-fatty-acid--CoA ligase (EC 6.2.1.3) (Long-chain| acyl-CoA synthetase) Length = 560 Score = 46.2 bits (108), Expect = 8e-05 Identities = 42/192 (21%), Positives = 75/192 (39%), Gaps = 19/192 (9%) Frame = +1 Query: 103 KWMTYGEAGTSRTAIGSGLICHGIPKGARVGLYFINRPEWTIVDNACSAYSYVSVPLYDT 282 K +T+ + T + + L C+G+ KG RV + N P+ I + V Sbjct: 48 KKLTFHDILTDALKLAAFLQCNGLQKGDRVAVMLPNCPQTVISYYGVLFAGGIVVQTNPL 107 Query: 283 LGPDAVQFIVNHASVEAIFCVPQTLSTLLSFITQMPCVRLI--VVVGGIDENMP------ 438 +++ + A V I TL L +M + ++ +++ + + +P Sbjct: 108 YTEHELEYQLRDAQVSVII----TLDLLFPKAIKMKTLSIVDQILITSVKDYLPFPKNIL 163 Query: 439 -----------SSPAAAGMEIITYSMLHRQGHMSPQPFRPPKPEDVATICYTSGTTGTPK 585 A + M + + P P+ D+A + YT GTTG PK Sbjct: 164 YPLTQKQKVHIDFDKTANIHTFASCMKQEKTELLTIPKIDPE-HDIAVLQYTGGTTGAPK 222 Query: 586 GAVLSHANFIAN 621 G +L+H N +AN Sbjct: 223 GVMLTHQNILAN 234
>SRFAB_BACSU (Q04747) Surfactin synthetase subunit 2| Length = 3587 Score = 46.2 bits (108), Expect = 8e-05 Identities = 41/169 (24%), Positives = 64/169 (37%) Frame = +1 Query: 109 MTYGEAGTSRTAIGSGLICHGIPKGARVGLYFINRPEWTIVDNACSAYSYVSVPLYDTLG 288 +TY E + + L+ HG+ KG + E + A VPL L Sbjct: 491 LTYRELNAAANRLARKLVEHGLQKGETAAIMNDRSVETVVGMLAVLKAGAAYVPLDPALP 550 Query: 289 PDAVQFIVNHASVEAIFCVPQTLSTLLSFITQMPCVRLIVVVGGIDENMPSSPAAAGMEI 468 D ++F+ +SV + L+ +L V V +D S AA + + Sbjct: 551 GDRLRFMAEDSSVRMV---------LIGNSYTGQAHQLQVPVLTLDIGFEESEAADNLNL 601 Query: 469 ITYSMLHRQGHMSPQPFRPPKPEDVATICYTSGTTGTPKGAVLSHANFI 615 P P D+A I YTSG+TG PKG ++ H + + Sbjct: 602 ------------------PSAPSDLAYIMYTSGSTGKPKGVMIEHKSIL 632 Score = 33.1 bits (74), Expect = 0.70 Identities = 13/24 (54%), Positives = 17/24 (70%) Frame = +1 Query: 538 DVATICYTSGTTGTPKGAVLSHAN 609 ++A + YTSGTTG PKG + H N Sbjct: 1638 NLAYVIYTSGTTGKPKGVQIEHRN 1661 Score = 30.0 bits (66), Expect = 5.9 Identities = 12/21 (57%), Positives = 17/21 (80%) Frame = +1 Query: 535 EDVATICYTSGTTGTPKGAVL 597 E++A + YTSGTTG PKG ++ Sbjct: 2691 ENLAYMIYTSGTTGQPKGVMV 2711
>ALKK_PSEOL (Q00594) Medium-chain-fatty-acid--CoA ligase (EC 6.2.1.-)| (Medium-chain acyl-CoA synthetase) Length = 546 Score = 46.2 bits (108), Expect = 8e-05 Identities = 50/194 (25%), Positives = 78/194 (40%), Gaps = 3/194 (1%) Frame = +1 Query: 43 QXXCRYLGTR-VHADGTIGDYKWMTYGEAGTSRTAIGSGLICHGIPKGARVGLYFINRPE 219 + RY G R V + T G+ + E + S L G+ R N Sbjct: 17 EHAARYHGAREVVSVETSGEVTRSCWKEVELRARKLASALGKMGLTPSDRCATIAWNNIR 76 Query: 220 WTIVDNACSAYSYVSVPLYDTLGPDAVQFIVNHASVEAIFCVPQTLSTLLSFITQMPCVR 399 V A S V + L + + +++NHA + + L + +P V+ Sbjct: 77 HLEVYYAVSGAGMVCHTINPRLFIEQITYVINHAEDKVVLLDDTFLPIIAEIHGSLPKVK 136 Query: 400 LIVVVGGIDENMPSSPAAAGME-IITYSMLHRQGHMSPQPFRPPKPEDVAT-ICYTSGTT 573 V++ + N A+A M +I Y L QG P E+ A+ +CYTSGTT Sbjct: 137 AFVLMAHNNSN-----ASAQMPGLIAYEDLIGQG--DDNYIWPDVDENEASSLCYTSGTT 189 Query: 574 GTPKGAVLSHANFI 615 G PKG + SH + + Sbjct: 190 GNPKGVLYSHRSTV 203
>ACSA_CAUCR (Q9A2I0) Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA| ligase) (Acyl-activating enzyme) Length = 647 Score = 44.7 bits (104), Expect = 2e-04 Identities = 39/184 (21%), Positives = 73/184 (39%), Gaps = 9/184 (4%) Frame = +1 Query: 94 GDYKWMTYGEAGTSRTAIGSGLICHGIPKGARVGLYFINRPEWTIVDNACSAYSYVSVPL 273 G +TYG+ + + L G+ KG RV +Y P + AC+ V + Sbjct: 104 GTSSTLTYGQLHEEVCRMANVLKAQGVKKGDRVTIYLPMVPLAAVAMLACARIGAVHSVV 163 Query: 274 YDTLGPDAVQFIVNHASVEAIFCVPQ---------TLSTLLSFITQMPCVRLIVVVGGID 426 + PD++ + + + + + + + P V ++++ Sbjct: 164 FGGFSPDSIAGRIQDCASHFVITADEGRRGGRRVPLKANIDEALKHCPWVGKVLMIRWTG 223 Query: 427 ENMPSSPAAAGMEIITYSMLHRQGHMSPQPFRPPKPEDVATICYTSGTTGTPKGAVLSHA 606 ++P AG +I+ + R + P P ED I YTSG+TG PKG + + Sbjct: 224 ADVPLK---AGRDIVWQDV--RDTVSADCPPEPMNAEDPLFILYTSGSTGKPKGVLHTTG 278 Query: 607 NFIA 618 ++A Sbjct: 279 GYLA 282
>ACSA_SYNEL (Q8DKH2) Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA| ligase) (Acyl-activating enzyme) Length = 656 Score = 44.7 bits (104), Expect = 2e-04 Identities = 46/189 (24%), Positives = 79/189 (41%), Gaps = 12/189 (6%) Frame = +1 Query: 82 DGTIGDYKWMTYGEAGTSRTAIGSGLICHGIPKGARVGLYFINRPEWTIVDNACSAYSYV 261 +G GD + +TY + + L G+ KG RVG+Y PE I AC+ Sbjct: 106 EGEPGDSRTLTYAQLHREVCQFANVLKQLGVKKGDRVGIYMPMIPEAAIAMLACARIGAP 165 Query: 262 SVPLYDTLGPDAVQFIVNHASV------------EAIFCVPQTLSTLLSFITQMPCVRLI 405 ++ +A++ + A +AI + + L+ +P V + Sbjct: 166 HSVVFGGFSAEALRDRLIDAQAKLVVTADGGWRKDAIVPLKDQVDKALAH-QGVPSVENV 224 Query: 406 VVVGGIDENMPSSPAAAGMEIITYSMLHRQGHMSPQPFRPPKPEDVATICYTSGTTGTPK 585 +VV + + P G + + + ++G + P P ED+ I YTSG+TG PK Sbjct: 225 LVVQRTQQPVTMVP---GRDHWWHDL--QKGVSADCPAEPMDSEDLLFILYTSGSTGKPK 279 Query: 586 GAVLSHANF 612 G V + A + Sbjct: 280 GVVHTTAGY 288
>ACSA2_PSEAE (Q9HV66) Acetyl-coenzyme A synthetase 2 (EC 6.2.1.1) (Acetate--CoA| ligase 2) (Acyl-activating enzyme 2) Length = 645 Score = 44.3 bits (103), Expect = 3e-04 Identities = 41/182 (22%), Positives = 70/182 (38%), Gaps = 9/182 (4%) Frame = +1 Query: 109 MTYGEAGTSRTAIGSGLICHGIPKGARVGLYFINRPEWTIVDNACSAYSYVSVPLYDTLG 288 +TY + + + + L G+ KG RV +Y PE AC+ V ++ Sbjct: 107 ITYRKLHHNVCRLANVLKSRGVEKGDRVCIYMPMIPEAAYAMLACARIGAVHSVVFGGFS 166 Query: 289 PDAVQFIVNHASVEAIFCVPQTL---------STLLSFITQMPCVRLIVVVGGIDENMPS 441 PD+++ + A + + + + + P V +VVV + Sbjct: 167 PDSLRDRILDADCRTVITADEGVRGGKYIPLKQNVEKALKDCPDVSTVVVV---ERTQGD 223 Query: 442 SPAAAGMEIITYSMLHRQGHMSPQPFRPPKPEDVATICYTSGTTGTPKGAVLSHANFIAN 621 P G +I + LH + P ED I YTSG+TG PKG + + ++ Sbjct: 224 IPWVEGRDIWYHEALHAAS--ADCPAEAMDAEDPLFILYTSGSTGKPKGVLHTTGGYLLG 281 Query: 622 VA 627 A Sbjct: 282 AA 283
>MENE_ENTFA (Q838K1) 2-succinylbenzoate--CoA ligase (EC 6.2.1.26) (OSB-CoA| synthetase) (o-succinylbenzoyl-CoA synthetase) Length = 485 Score = 44.3 bits (103), Expect = 3e-04 Identities = 23/51 (45%), Positives = 31/51 (60%), Gaps = 1/51 (1%) Frame = +1 Query: 481 MLHRQGHMSPQPFRPPKP-EDVATICYTSGTTGTPKGAVLSHANFIANVAG 630 M+ +Q +S Q F+ P E VA+I YTSGTTG PKG + N +A+ G Sbjct: 120 MIKKQHSLSHQEFQQPSDLESVASIMYTSGTTGQPKGVLQRFKNHLASARG 170
>LCFA_ECOLI (P69451) Long-chain-fatty-acid--CoA ligase (EC 6.2.1.3) (Long-chain| acyl-CoA synthetase) (Acyl-CoA synthetase) Length = 561 Score = 44.3 bits (103), Expect = 3e-04 Identities = 42/170 (24%), Positives = 69/170 (40%), Gaps = 18/170 (10%) Frame = +1 Query: 169 GIPKGARVGLYFINRPEWTIVDNACSAYSYVSVPLYDTLGPDAVQFIVNHASVEAIFCVP 348 G+ KG RV L N ++ + + V + P ++ +N + AI V Sbjct: 70 GLKKGDRVALMMPNLLQYPVALFGILRAGMIVVNVNPLYTPRELEHQLNDSGASAIVIVS 129 Query: 349 QTLSTLLSFITQMPCVRLIVVVGGIDENMPSSPAAAGMEIITY----------------- 477 TL + + +I+ G + + ++ ++ Y Sbjct: 130 NFAHTLEKVVDKTAVQHVILTRMG--DQLSTAKGTVVNFVVKYIKRLVPKYHLPDAISFR 187 Query: 478 SMLHRQGHMSPQPFRPPK-PEDVATICYTSGTTGTPKGAVLSHANFIANV 624 S LH M Q +P PED+A + YT GTTG KGA+L+H N +AN+ Sbjct: 188 SALHNGYRM--QYVKPELVPEDLAFLQYTGGTTGVAKGAMLTHRNMLANL 235
>LCFA_ECOL6 (P69452) Long-chain-fatty-acid--CoA ligase (EC 6.2.1.3) (Long-chain| acyl-CoA synthetase) (Acyl-CoA synthetase) Length = 561 Score = 44.3 bits (103), Expect = 3e-04 Identities = 42/170 (24%), Positives = 69/170 (40%), Gaps = 18/170 (10%) Frame = +1 Query: 169 GIPKGARVGLYFINRPEWTIVDNACSAYSYVSVPLYDTLGPDAVQFIVNHASVEAIFCVP 348 G+ KG RV L N ++ + + V + P ++ +N + AI V Sbjct: 70 GLKKGDRVALMMPNLLQYPVALFGILRAGMIVVNVNPLYTPRELEHQLNDSGASAIVIVS 129 Query: 349 QTLSTLLSFITQMPCVRLIVVVGGIDENMPSSPAAAGMEIITY----------------- 477 TL + + +I+ G + + ++ ++ Y Sbjct: 130 NFAHTLEKVVDKTAVQHVILTRMG--DQLSTAKGTVVNFVVKYIKRLVPKYHLPDAISFR 187 Query: 478 SMLHRQGHMSPQPFRPPK-PEDVATICYTSGTTGTPKGAVLSHANFIANV 624 S LH M Q +P PED+A + YT GTTG KGA+L+H N +AN+ Sbjct: 188 SALHNGYRM--QYVKPELVPEDLAFLQYTGGTTGVAKGAMLTHRNMLANL 235
>4CL3_ARATH (Q9S777) 4-coumarate--CoA ligase 3 (EC 6.2.1.12) (4CL 3) (At4CL3)| (4-coumaroyl-CoA synthase 3) Length = 561 Score = 44.3 bits (103), Expect = 3e-04 Identities = 50/186 (26%), Positives = 72/186 (38%), Gaps = 11/186 (5%) Frame = +1 Query: 103 KWMTYGEAGTSRTAIGSGLICHGIPKGARVGLYFINRPEWTIVDNACSAYS--------- 255 K TYGE + SGL GI KG + + N E+ S Sbjct: 74 KSYTYGETHLICRRVASGLYKLGIRKGDVIMILLQNSAEFVFSFMGASMIGAVSTTANPF 133 Query: 256 YVSVPLYDTLGPDAVQFIVNHAS-VEAIFCVPQTLSTLLSFITQMPCVRLIVVVGGIDEN 432 Y S LY L + I+ H+ V+ + + L L+ IT DE Sbjct: 134 YTSQELYKQLKSSGAKLIITHSQYVDKL----KNLGENLTLITT-------------DEP 176 Query: 433 MPSSPAAAGMEIITYSMLHRQGHMSP-QPFRPPKPEDVATICYTSGTTGTPKGAVLSHAN 609 P + + +S L +P Q +D A + ++SGTTG PKG VL+H + Sbjct: 177 TPEN-------CLPFSTLITDDETNPFQETVDIGGDDAAALPFSSGTTGLPKGVVLTHKS 229 Query: 610 FIANVA 627 I +VA Sbjct: 230 LITSVA 235
>LCFA_ECO57 (Q8XDR6) Long-chain-fatty-acid--CoA ligase (EC 6.2.1.3) (Long-chain| acyl-CoA synthetase) (Acyl-CoA synthetase) Length = 561 Score = 43.9 bits (102), Expect = 4e-04 Identities = 42/170 (24%), Positives = 69/170 (40%), Gaps = 18/170 (10%) Frame = +1 Query: 169 GIPKGARVGLYFINRPEWTIVDNACSAYSYVSVPLYDTLGPDAVQFIVNHASVEAIFCVP 348 G+ KG RV L N ++ + + V + P ++ +N + AI V Sbjct: 70 GLKKGDRVALMMPNLLQYPVALFGILRAGMIVVNVNPLYTPRELEHQLNDSGASAIVIVS 129 Query: 349 QTLSTLLSFITQMPCVRLIVVVGGIDENMPSSPAAAGMEIITY----------------- 477 TL + + +I+ G + + ++ ++ Y Sbjct: 130 NFAHTLEKVVDKTAVQHVILTRMG--DQLSTAKGTLVNFVVKYIKRLVPKYHLPDAISFR 187 Query: 478 SMLHRQGHMSPQPFRPPK-PEDVATICYTSGTTGTPKGAVLSHANFIANV 624 S LH M Q +P PED+A + YT GTTG KGA+L+H N +AN+ Sbjct: 188 SALHNGYRM--QYVKPELVPEDLAFLQYTGGTTGVAKGAMLTHRNMLANL 235
>AAS_ERWCT (Q6D107) AAS bifunctional protein [Includes:| 2-acylglycerophosphoethanolamine acyltransferase (EC 2.3.1.40) (Acyl-[acyl-carrier-protein]--phospholipid O-acyltransferase) (2-acyl-GPE acyltransferase); Acyl-[acyl-carrier-protein] synthetase (EC 6 Length = 738 Score = 43.5 bits (101), Expect = 5e-04 Identities = 18/34 (52%), Positives = 24/34 (70%) Frame = +1 Query: 523 PPKPEDVATICYTSGTTGTPKGAVLSHANFIANV 624 P KP+D A + +TSG+ G PKG V SH + +ANV Sbjct: 361 PQKPDDAAIVLFTSGSEGNPKGVVHSHDSLLANV 394
>TYCC_BREPA (O30409) Tyrocidine synthetase 3 (Tyrocidine synthetase III)| [Includes: ATP-dependent asparagine adenylase (AsnA) (Asparagine activase); ATP-dependent glutamine adenylase (GlnA) (Glutamine activase); ATP-dependent tyrosine adenylase (TyrA) (Ty Length = 6486 Score = 43.5 bits (101), Expect = 5e-04 Identities = 21/33 (63%), Positives = 26/33 (78%) Frame = +1 Query: 529 KPEDVATICYTSGTTGTPKGAVLSHANFIANVA 627 +PE+VA I YTSGTTG PKG V+ H ++ ANVA Sbjct: 4748 QPENVAYIIYTSGTTGKPKGVVIEHRSY-ANVA 4779 Score = 40.4 bits (93), Expect = 0.004 Identities = 15/29 (51%), Positives = 23/29 (79%) Frame = +1 Query: 529 KPEDVATICYTSGTTGTPKGAVLSHANFI 615 KP+D+A + YTSG+TG PKGA+++H + Sbjct: 602 KPDDLAYMIYTSGSTGNPKGAMITHQGLV 630 Score = 38.1 bits (87), Expect = 0.022 Identities = 16/29 (55%), Positives = 20/29 (68%) Frame = +1 Query: 538 DVATICYTSGTTGTPKGAVLSHANFIANV 624 D+A I YTSGTTG PKG ++ H + NV Sbjct: 2680 DLAYIIYTSGTTGKPKGVMVEHRGIVNNV 2708 Score = 37.4 bits (85), Expect = 0.037 Identities = 14/29 (48%), Positives = 20/29 (68%) Frame = +1 Query: 529 KPEDVATICYTSGTTGTPKGAVLSHANFI 615 +P D+A + YTSGTTG PKG ++ H + Sbjct: 5798 QPTDLAYVIYTSGTTGKPKGVMIPHQGIV 5826 Score = 36.2 bits (82), Expect = 0.082 Identities = 34/165 (20%), Positives = 62/165 (37%) Frame = +1 Query: 109 MTYGEAGTSRTAIGSGLICHGIPKGARVGLYFINRPEWTIVDNACSAYSYVSVPLYDTLG 288 +TY E + L HG +G+ P + A P+ + Sbjct: 1526 LTYRELNARANQLARLLRSHGTGPDTLIGIMVDRSPGMVVGMLAVLKAGGAYTPIDPSYP 1585 Query: 289 PDAVQFIVNHASVEAIFCVPQTLSTLLSFITQMPCVRLIVVVGGIDENMPSSPAAAGMEI 468 P+ +Q++++ + I + L L ++ ++ V + G D N+ + AG + Sbjct: 1586 PERIQYMLSDSQAP-ILLTQRHLQELAAYQGEIIDVDEEAIYTGADTNLDN---VAGKD- 1640 Query: 469 ITYSMLHRQGHMSPQPFRPPKPEDVATICYTSGTTGTPKGAVLSH 603 D+A + YTSG+TG PKG ++SH Sbjct: 1641 -----------------------DLAYVIYTSGSTGNPKGVMISH 1662 Score = 34.3 bits (77), Expect = 0.31 Identities = 13/24 (54%), Positives = 18/24 (75%) Frame = +1 Query: 538 DVATICYTSGTTGTPKGAVLSHAN 609 D+A + YTSG+TG PKG ++ H N Sbjct: 3716 DLAYVMYTSGSTGKPKGVMVEHRN 3739
>ACSA_SYNY3 (Q55404) Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA| ligase) (Acyl-activating enzyme) Length = 653 Score = 43.1 bits (100), Expect = 7e-04 Identities = 41/176 (23%), Positives = 65/176 (36%), Gaps = 5/176 (2%) Frame = +1 Query: 82 DGTIGDYKWMTYGEAGTSRTAIGSGLICHGIPKGARVGLYFINRPEWTIVDNACSAYSYV 261 +G GD + +TY + + L G+ KG RV +Y PE I ACS Sbjct: 105 EGEPGDSRIITYAQLHREVCQFANALKSLGVQKGDRVAIYLPMIPEAAITMLACSRIGAP 164 Query: 262 SVPLYDTLGPDAVQFIVNHASVEAIFCVPQTLSTLLSFITQMPCVRLIVVVGGIDENMPS 441 ++ +A++ + A + + + + + + EN+ Sbjct: 165 HSVVFGGFSAEALRDRLVDAEAKLVITADGGFRKDKAIALKQEVDKALEHGAPSVENVIV 224 Query: 442 SPAAAGMEIITYSMLHRQGHMSPQ-----PFRPPKPEDVATICYTSGTTGTPKGAV 594 +T H + PQ P P ED+ I YTSG+TG PKG V Sbjct: 225 VQRTKADVTMTAGRDHWWHELQPQQSAHCPAEPIDSEDMLFILYTSGSTGKPKGVV 280
>ACSA_CHLTE (Q8KBY0) Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA| ligase) (Acyl-activating enzyme) Length = 659 Score = 43.1 bits (100), Expect = 7e-04 Identities = 45/197 (22%), Positives = 78/197 (39%), Gaps = 15/197 (7%) Frame = +1 Query: 82 DGTIGDYKWMTYGEAGTSRTAIGSGLICHGIPKGARVGLYFINRPEWTIVDNACSAYSYV 261 +G G+ + +TYGE + + L GI G +V +Y PE I AC+ V Sbjct: 113 EGEEGNERILTYGELHRQVSKFANVLKIAGIKPGDKVAIYMGMVPELVIAVLACARVGAV 172 Query: 262 SVPLYDTLGPDAVQFIVNHASVEAIFCVPQT--------LSTLL-SFITQMPCVRLIVVV 414 ++ A+ VN + + + C T L ++ I P V+ ++V+ Sbjct: 173 HNVIFAGFAAHAITERVNDSRAKIVICADGTRRRGSTINLKNIVDEAIINTPSVKNVIVL 232 Query: 415 GGIDENMPSSPAAAGMEIITYSMLHRQGH----MSPQPFRPPK--PEDVATICYTSGTTG 576 G EI + + H ++ P + E + YTSG+TG Sbjct: 233 -----------KVTGEEIHMHDGMDHWWHDLMGLAVDECEPAQVDSEHPLFLLYTSGSTG 281 Query: 577 TPKGAVLSHANFIANVA 627 PKG + + A ++ + A Sbjct: 282 KPKGILHTTAGYMVHAA 298
>4CL4_ARATH (Q9LU36) 4-coumarate--CoA ligase 4 (EC 6.2.1.12) (4CL 4) (At4CL4)| (4-coumaroyl-CoA synthase 4) (4-coumarate CoA ligase isoform 5) Length = 570 Score = 42.7 bits (99), Expect = 9e-04 Identities = 44/185 (23%), Positives = 83/185 (44%), Gaps = 3/185 (1%) Frame = +1 Query: 82 DGTIGDYKWMTYGEAGTSRTAIGSGLICHGIPKGARVGLYFINRPEWTIVDNACSAYSYV 261 DG G + +TY + T+ I +G+ GI G V L N PE+ + A + V Sbjct: 67 DGATG--RILTYADVQTNMRRIAAGIHRLGIRHGDVVMLLLPNSPEFALSFLAVAYLGAV 124 Query: 262 SVPLYDTLGPDAVQFIVNHASVEAIFCVPQTLSTLLSFITQMPCVRLIVVVGGIDENMPS 441 S T P Q + + + + T L+ +T + +++V +D++ + Sbjct: 125 ST----TANPFYTQPEIAKQAKASAAKMIITKKCLVDKLTNLKNDGVLIVC--LDDDGDN 178 Query: 442 SPAAAGME-IITYSMLHRQGHMSPQPFRPPK--PEDVATICYTSGTTGTPKGAVLSHANF 612 ++ + ++++ L + PK PED + Y+SGTTG PKG +++H Sbjct: 179 GVVSSSDDGCVSFTELTQADETE---LLKPKISPEDTVAMPYSSGTTGLPKGVMITHKGL 235 Query: 613 IANVA 627 + ++A Sbjct: 236 VTSIA 240
>GRSB_BREBE (P0C064) Gramicidin S synthetase 2 (Gramicidin S synthetase II)| [Includes: ATP-dependent proline adenylase (ProA) (Proline activase); ATP-dependent valine adenylase (ValA) (Valine activase); ATP-dependent ornithine adenylase (OrnA) (Ornithine Length = 4449 Score = 42.7 bits (99), Expect = 9e-04 Identities = 18/33 (54%), Positives = 26/33 (78%) Frame = +1 Query: 529 KPEDVATICYTSGTTGTPKGAVLSHANFIANVA 627 +P+D+A I YTSGTTG PKG ++ H +++ NVA Sbjct: 2679 RPQDIAYIIYTSGTTGKPKGVMIEHQSYV-NVA 2710 Score = 38.1 bits (87), Expect = 0.022 Identities = 16/27 (59%), Positives = 19/27 (70%) Frame = +1 Query: 535 EDVATICYTSGTTGTPKGAVLSHANFI 615 ED+ I YTSGTTG PKG +L H N + Sbjct: 605 EDLFYIIYTSGTTGKPKGVMLEHKNIV 631 Score = 36.2 bits (82), Expect = 0.082 Identities = 15/26 (57%), Positives = 19/26 (73%) Frame = +1 Query: 538 DVATICYTSGTTGTPKGAVLSHANFI 615 D+A I YTSGTTG PKG ++ H + I Sbjct: 3728 DLAYIIYTSGTTGKPKGVMIEHQSII 3753 Score = 35.8 bits (81), Expect = 0.11 Identities = 15/26 (57%), Positives = 19/26 (73%) Frame = +1 Query: 538 DVATICYTSGTTGTPKGAVLSHANFI 615 D+A I YTSG+TG PKG ++ H N I Sbjct: 1646 DLAYIMYTSGSTGKPKGVMVEHRNVI 1671
>TYCA_BREPA (P09095) Tyrocidine synthetase 1 (Tyrocidine synthetase I)| [Includes: ATP-dependent D-phenylalanine adenylase (D-PheA) (D-phenylalanine activase); Phenylalanine racemase [ATP-hydrolyzing] (EC 5.1.1.11)] Length = 1088 Score = 42.7 bits (99), Expect = 9e-04 Identities = 20/35 (57%), Positives = 25/35 (71%) Frame = +1 Query: 520 RPPKPEDVATICYTSGTTGTPKGAVLSHANFIANV 624 +P KP D+A + YTSGTTG PKG +L H IAN+ Sbjct: 165 QPSKPTDLAYVIYTSGTTGKPKGTMLEHKG-IANL 198
>4CL_VANPL (O24540) 4-coumarate--CoA ligase (EC 6.2.1.12) (4CL)| (4-coumaroyl-CoA synthase) Length = 553 Score = 42.4 bits (98), Expect = 0.001 Identities = 41/172 (23%), Positives = 67/172 (38%) Frame = +1 Query: 112 TYGEAGTSRTAIGSGLICHGIPKGARVGLYFINRPEWTIVDNACSAYSYVSVPLYDTLGP 291 TY + +GSGL GI +G + + N PE+ S +S Sbjct: 58 TYADVELISRRVGSGLSKLGIKQGDTIMILLPNSPEFVFAFLGASFIGSISTMANPFFTS 117 Query: 292 DAVQFIVNHASVEAIFCVPQTLSTLLSFITQMPCVRLIVVVGGIDENMPSSPAAAGMEII 471 V ++ + I T + + C + ++ ID + AA I+ Sbjct: 118 TEVIKQAKASNAKLII----TQGCYVDKVKDYACENGVKIIS-IDTTTTADDAA---NIL 169 Query: 472 TYSMLHRQGHMSPQPFRPPKPEDVATICYTSGTTGTPKGAVLSHANFIANVA 627 +S L + P P+ V + Y+SGTTG PKG +L+H + +VA Sbjct: 170 HFSELTGADE-NEMPKVEISPDGVVALPYSSGTTGLPKGVMLTHKGLVTSVA 220
>ACVS_EMENI (P27742) N-(5-amino-5-carboxypentanoyl)-L-cysteinyl-D-valine| synthase (EC 6.3.2.26) (Delta-(L-alpha-aminoadipyl)-L-cysteinyl-D-valine synthetase) (ACV synthetase) (ACVS) Length = 3770 Score = 41.6 bits (96), Expect = 0.002 Identities = 49/196 (25%), Positives = 78/196 (39%), Gaps = 10/196 (5%) Frame = +1 Query: 67 TRVHADGTIGDYK--WMTYGEAGTSRTAIGSGLICHGIPKGARVGLYFINRPEWTIVD-- 234 T++H D YK +TYGE L GI V L F+ + E IV Sbjct: 329 TQLHEDKVAIVYKRRQLTYGELNAQANCFAHYLRSIGILPEQLVAL-FLEKSENLIVTIL 387 Query: 235 ---NACSAYSYVSVPLYDTLGPDAVQFIVNHASVEAIFCVPQTLSTLLSFIT---QMPCV 396 + +AY VP+ T + V+F++ + I L S + ++ + Sbjct: 388 GIWKSGAAY----VPIDPTYPDERVRFVLEDTQAKVIIASNHLAERLQSEVISDRELSII 443 Query: 397 RLIVVVGGIDENMPSSPAAAGMEIITYSMLHRQGHMSPQPFRPPKPEDVATICYTSGTTG 576 RL + ID+ + P A + S+ +Q +A + YTSGTTG Sbjct: 444 RLEHCLSAIDQQPSTFPRA---NLRDPSLTSKQ---------------LAYVTYTSGTTG 485 Query: 577 TPKGAVLSHANFIANV 624 PKG + H N + ++ Sbjct: 486 FPKGILKQHTNVVNSI 501 Score = 34.3 bits (77), Expect = 0.31 Identities = 14/22 (63%), Positives = 17/22 (77%) Frame = +1 Query: 538 DVATICYTSGTTGTPKGAVLSH 603 D+A I YTSGTTG PKG ++ H Sbjct: 1559 DLAYIIYTSGTTGKPKGVMVEH 1580
>ACS2L_HUMAN (Q9NUB1) Acetyl-coenzyme A synthetase 2-like, mitochondrial| precursor (EC 6.2.1.1) (Acetate--CoA ligase 2) (Acetyl-CoA synthetase 2) (Acyl-CoA synthetase short-chain family member 1) Length = 689 Score = 41.2 bits (95), Expect = 0.003 Identities = 40/185 (21%), Positives = 70/185 (37%), Gaps = 12/185 (6%) Frame = +1 Query: 109 MTYGEAGTSRTAIGSGLICHGIPKGARVGLYFINRPEWTIVDNACSAYSYVSVPLYDTLG 288 +TY E + + + L HG+ +G RV +Y P AC+ V ++ Sbjct: 141 ITYRELLETTCRLANTLKRHGVHRGDRVAIYMPVSPLAVAAMLACARIGAVHTVIFAGFS 200 Query: 289 PDAVQFIVNHASVEAIFCVPQTL---------STLLSFITQMPCVRLIVVVGGIDENMPS 441 +++ +N A + + Q L + + P V+ ++V D + Sbjct: 201 AESLAGRINDAKCKVVITFNQGLRGGRVVELKKIVDEAVKHCPTVQHVLVAHRTDNKVHM 260 Query: 442 SPAAAGMEIITYSMLHRQGHMSPQPFRPPKP---EDVATICYTSGTTGTPKGAVLSHANF 612 +E Q P P+ ED+ + YTSG+TG PKG V + A + Sbjct: 261 GDLDVPLE---------QEMAKEDPVCAPESMGSEDMLFMLYTSGSTGMPKGIVHTQAGY 311 Query: 613 IANVA 627 + A Sbjct: 312 LLYAA 316
>LCFA_HAEIN (P46450) Long-chain-fatty-acid--CoA ligase (EC 6.2.1.3) (Long-chain| acyl-CoA synthetase) Length = 562 Score = 41.2 bits (95), Expect = 0.003 Identities = 18/30 (60%), Positives = 22/30 (73%) Frame = +1 Query: 535 EDVATICYTSGTTGTPKGAVLSHANFIANV 624 ED+A + YT GTTG KGA+L+H N I NV Sbjct: 206 EDLAFLQYTGGTTGVAKGAMLTHGNIITNV 235
>4CL_PINTA (P41636) 4-coumarate--CoA ligase (EC 6.2.1.12) (4CL)| (4-coumaroyl-CoA synthase) Length = 537 Score = 41.2 bits (95), Expect = 0.003 Identities = 16/32 (50%), Positives = 24/32 (75%) Frame = +1 Query: 532 PEDVATICYTSGTTGTPKGAVLSHANFIANVA 627 P+DV + Y+SGTTG PKG +L+H +++VA Sbjct: 180 PDDVVALPYSSGTTGLPKGVMLTHKGLVSSVA 211
>SID2_USTMA (O43103) Ferrichrome siderophore peptide synthetase (EC 6.-.-.-)| Length = 3947 Score = 41.2 bits (95), Expect = 0.003 Identities = 19/34 (55%), Positives = 24/34 (70%) Frame = +1 Query: 529 KPEDVATICYTSGTTGTPKGAVLSHANFIANVAG 630 + +DVA I YTSG+TG PKG +L+ AN A V G Sbjct: 1539 RSDDVAFIIYTSGSTGKPKGCLLTQANLAAAVEG 1572
>4CL2_TOBAC (O24146) 4-coumarate--CoA ligase 2 (EC 6.2.1.12) (4CL 2)| (4-coumaroyl-CoA synthase 2) Length = 542 Score = 41.2 bits (95), Expect = 0.003 Identities = 16/33 (48%), Positives = 24/33 (72%) Frame = +1 Query: 529 KPEDVATICYTSGTTGTPKGAVLSHANFIANVA 627 +P+DV + Y+SGTTG PKG +L+H + +VA Sbjct: 179 QPDDVVALPYSSGTTGLPKGVMLTHKGLVTSVA 211
>4CL2_SOLTU (P31685) 4-coumarate--CoA ligase 2 (EC 6.2.1.12) (4CL 2)| (4-coumaroyl-CoA synthase 2) Length = 545 Score = 41.2 bits (95), Expect = 0.003 Identities = 16/33 (48%), Positives = 24/33 (72%) Frame = +1 Query: 529 KPEDVATICYTSGTTGTPKGAVLSHANFIANVA 627 +P+DV + Y+SGTTG PKG +L+H + +VA Sbjct: 182 QPDDVVALPYSSGTTGLPKGVMLTHKGLVTSVA 214
>4CL1_SOLTU (P31684) 4-coumarate--CoA ligase 1 (EC 6.2.1.12) (4CL 1)| (4-coumaroyl-CoA synthase 1) Length = 545 Score = 41.2 bits (95), Expect = 0.003 Identities = 16/33 (48%), Positives = 24/33 (72%) Frame = +1 Query: 529 KPEDVATICYTSGTTGTPKGAVLSHANFIANVA 627 +P+DV + Y+SGTTG PKG +L+H + +VA Sbjct: 182 QPDDVVALPYSSGTTGLPKGVMLTHKGLVTSVA 214
>ACVS_CEPAC (P25464) N-(5-amino-5-carboxypentanoyl)-L-cysteinyl-D-valine synthase| (EC 6.3.2.26) (Delta-(L-alpha-aminoadipyl)-L-cysteinyl-D-valine synthetase) (ACV synthetase) (ACVS) Length = 3712 Score = 41.2 bits (95), Expect = 0.003 Identities = 19/37 (51%), Positives = 23/37 (62%), Gaps = 3/37 (8%) Frame = +1 Query: 502 MSPQPFRPP---KPEDVATICYTSGTTGTPKGAVLSH 603 + P P P KP D+A I YTSGTTG PKG ++ H Sbjct: 1492 LPPSPVHPVSNCKPSDLAYIMYTSGTTGNPKGVMVEH 1528 Score = 39.7 bits (91), Expect = 0.007 Identities = 25/71 (35%), Positives = 37/71 (52%), Gaps = 4/71 (5%) Frame = +1 Query: 415 GGIDENMPS----SPAAAGMEIITYSMLHRQGHMSPQPFRPPKPEDVATICYTSGTTGTP 582 GG N+PS SP T + L++Q +P KP D+A + +TSGTTG P Sbjct: 2547 GGTVANVPSVVLDSPE-------TLACLNQQSKENPTT-STQKPSDLAYVIFTSGTTGKP 2598 Query: 583 KGAVLSHANFI 615 KG ++ H + + Sbjct: 2599 KGVLVEHQSVV 2609 Score = 37.0 bits (84), Expect = 0.048 Identities = 41/180 (22%), Positives = 72/180 (40%), Gaps = 6/180 (3%) Frame = +1 Query: 103 KWMTYGEAGTSRTAIGSGLICHGIPKGARVGLYFINRPEWTIVDNACSAYSYVS-VPLYD 279 K +TY E + L+ GI VGL F+++ E I S + VP+ Sbjct: 284 KRITYEELNAMANRLAHHLVSSGIQTEQLVGL-FLDKTELMIATILGIWKSGAAHVPIDP 342 Query: 280 TLGPDAVQFIVNHASVEAIFCVPQTLSTLLSFITQMPCVRLIVVVGGIDENMPSSPAAAG 459 + V+F++N + + + + L + +R+I G Sbjct: 343 GYPDERVKFVLNDTKAQVVIASQRHVDRLRAEAVGGQHLRII-----------------G 385 Query: 460 MEIITYSMLHRQGHMSPQP-----FRPPKPEDVATICYTSGTTGTPKGAVLSHANFIANV 624 +E + + L +Q SP+ P + +A + YTSGTTG PKG H + + ++ Sbjct: 386 LESL-FDNLAQQTQHSPETSGNLTHLPLNSKQLAYVTYTSGTTGFPKGIYKEHTSVVNSI 444
>ANGR_VIBAN (P19828) Protein angR| Length = 1048 Score = 41.2 bits (95), Expect = 0.003 Identities = 25/73 (34%), Positives = 37/73 (50%), Gaps = 3/73 (4%) Frame = +1 Query: 394 VRLIVVVGGIDENMPSSPAAAGMEIITYSMLHRQGHMSPQPFRPPK---PEDVATICYTS 564 + +I++ +N PS+ + L Q + +P R P+ P A I YTS Sbjct: 551 INVILINESDSKNSPSNDL--------FFFLDWQTAIKSEPMRSPQDVAPSQPAYIIYTS 602 Query: 565 GTTGTPKGAVLSH 603 G+TGTPKG V+SH Sbjct: 603 GSTGTPKGVVISH 615
>ACVS_NOCLA (P27743) N-(5-amino-5-carboxypentanoyl)-L-cysteinyl-D-valine synthase| (EC 6.3.2.26) (Delta-(L-alpha-aminoadipyl)-L-cysteinyl-D-valine synthetase) (ACV synthetase) (ACVS) Length = 3649 Score = 41.2 bits (95), Expect = 0.003 Identities = 24/83 (28%), Positives = 36/83 (43%) Frame = +1 Query: 367 LSFITQMPCVRLIVVVGGIDENMPSSPAAAGMEIITYSMLHRQGHMSPQPFRPPKPEDVA 546 +SF+ R +VV I + S A G ++ +LH + P D+A Sbjct: 1435 ISFMLSDTAAR-VVVTNEIHSDRLRSLAETGTPVLEIELLHLDDQPAVNPVTETTSTDLA 1493 Query: 547 TICYTSGTTGTPKGAVLSHANFI 615 YTSGTTG PK ++ H + Sbjct: 1494 YAIYTSGTTGKPKAVLVEHRGVV 1516 Score = 34.3 bits (77), Expect = 0.31 Identities = 18/59 (30%), Positives = 29/59 (49%), Gaps = 3/59 (5%) Frame = +1 Query: 463 EIITYSMLHRQGHMSPQPFRPPKPEDVATICYTSGTTGTPKGAVLSHA---NFIANVAG 630 +++ L G + P ++A YTSGTTG PK ++SH +F A ++G Sbjct: 2518 DVLDLEQLDLTGEPAENPVTETTSTELAYAIYTSGTTGKPKAVLVSHGSVDSFRAQLSG 2576 Score = 30.8 bits (68), Expect = 3.5 Identities = 13/29 (44%), Positives = 18/29 (62%) Frame = +1 Query: 538 DVATICYTSGTTGTPKGAVLSHANFIANV 624 D A + YTSGTTG PKG H + + ++ Sbjct: 403 DRAYVTYTSGTTGVPKGVPKYHYSVVNSI 431
>4CL1_TOBAC (O24145) 4-coumarate--CoA ligase 1 (EC 6.2.1.12) (4CL 1)| (4-coumaroyl-CoA synthase 1) Length = 547 Score = 41.2 bits (95), Expect = 0.003 Identities = 16/33 (48%), Positives = 24/33 (72%) Frame = +1 Query: 529 KPEDVATICYTSGTTGTPKGAVLSHANFIANVA 627 +P+DV + Y+SGTTG PKG +L+H + +VA Sbjct: 184 QPDDVVALPYSSGTTGLPKGVMLTHKGLVTSVA 216
>AAS_YERPS (Q667F1) AAS bifunctional protein [Includes:| 2-acylglycerophosphoethanolamine acyltransferase (EC 2.3.1.40) (Acyl-[acyl-carrier-protein]--phospholipid O-acyltransferase) (2-acyl-GPE acyltransferase); Acyl-[acyl-carrier-protein] synthetase (EC 6 Length = 718 Score = 40.8 bits (94), Expect = 0.003 Identities = 18/34 (52%), Positives = 24/34 (70%) Frame = +1 Query: 523 PPKPEDVATICYTSGTTGTPKGAVLSHANFIANV 624 P + +D A I +TSG+ G PKG V SHA+ +ANV Sbjct: 361 PQQADDSALILFTSGSEGNPKGVVHSHASLLANV 394
>ACVS1_PENCH (P19787) N-(5-amino-5-carboxypentanoyl)-L-cysteinyl-D-valine| synthase (EC 6.3.2.26) (Delta-(L-alpha-aminoadipyl)-L-cysteinyl-D-valine synthetase) (ACV synthetase) (ACVS) Length = 3746 Score = 40.8 bits (94), Expect = 0.003 Identities = 44/184 (23%), Positives = 75/184 (40%), Gaps = 8/184 (4%) Frame = +1 Query: 97 DYKWMTYGEAGTSRTAIGSGLICHGIPKGARVGLYFINRPEWTIVD-----NACSAYSYV 261 D + +TYGE ++ L GI V L F+++ E IV + +AY Sbjct: 314 DERELTYGELNAQGNSLARYLRSIGILPEQLVAL-FLDKSEKLIVTILGVWKSGAAY--- 369 Query: 262 SVPLYDTLGPDAVQFIVNHASVEAIFCVPQTLSTLLSFIT---QMPCVRLIVVVGGIDEN 432 VP+ T + V+F+++ AI Q + L + + +RL ++ + ++ Sbjct: 370 -VPIDPTYPDERVRFVLDDTKARAIIASNQHVERLQREVIGDRNLCIIRLEPLLASLAQD 428 Query: 433 MPSSPAAAGMEIITYSMLHRQGHMSPQPFRPPKPEDVATICYTSGTTGTPKGAVLSHANF 612 PA H + P + +A + YTSGTTG PKG H N Sbjct: 429 SSKFPA------------HNLDDL------PLTSQQLAYVTYTSGTTGFPKGIFKQHTNV 470 Query: 613 IANV 624 + ++ Sbjct: 471 VNSI 474 Score = 34.3 bits (77), Expect = 0.31 Identities = 16/33 (48%), Positives = 20/33 (60%) Frame = +1 Query: 505 SPQPFRPPKPEDVATICYTSGTTGTPKGAVLSH 603 +P P + D+A I YTSGTTG PKG + H Sbjct: 1524 NPSPLS--RSTDLAYIIYTSGTTGRPKGVTVEH 1554
>PKSJ_BACSU (P40806) Putative polyketide synthase pksJ (PKS)| Length = 5045 Score = 40.8 bits (94), Expect = 0.003 Identities = 17/33 (51%), Positives = 24/33 (72%) Frame = +1 Query: 532 PEDVATICYTSGTTGTPKGAVLSHANFIANVAG 630 PED+A + TSG+TGTPK +L+H N ++ V G Sbjct: 186 PEDLALLLLTSGSTGTPKAVMLNHRNIMSMVKG 218 Score = 36.2 bits (82), Expect = 0.082 Identities = 16/38 (42%), Positives = 25/38 (65%), Gaps = 3/38 (7%) Frame = +1 Query: 520 RPPKPEDVATICYTSGTTGTPKGAVLSH---ANFIANV 624 R PE++A + YTSG+TG PKG ++ H NF+ ++ Sbjct: 1296 RTVTPENLAYVIYTSGSTGKPKGVMIPHKALTNFLVSM 1333
>ACVS2_PENCH (P26046) N-(5-amino-5-carboxypentanoyl)-L-cysteinyl-D-valine| synthase (EC 6.3.2.26) (Delta-(L-alpha-aminoadipyl)-L-cysteinyl-D-valine synthetase) (ACV synthetase) (ACVS) Length = 3791 Score = 40.8 bits (94), Expect = 0.003 Identities = 44/184 (23%), Positives = 75/184 (40%), Gaps = 8/184 (4%) Frame = +1 Query: 97 DYKWMTYGEAGTSRTAIGSGLICHGIPKGARVGLYFINRPEWTIVD-----NACSAYSYV 261 D + +TYGE ++ L GI V L F+++ E IV + +AY Sbjct: 344 DERELTYGELNAQGNSLARYLRSIGILPEQLVAL-FLDKSEKLIVTILGVWKSGAAY--- 399 Query: 262 SVPLYDTLGPDAVQFIVNHASVEAIFCVPQTLSTLLSFIT---QMPCVRLIVVVGGIDEN 432 VP+ T + V+F+++ AI Q + L + + +RL ++ + ++ Sbjct: 400 -VPIDPTYPDERVRFVLDDTKARAIIASNQHVERLQREVIGDRNLCIIRLEPLLASLAQD 458 Query: 433 MPSSPAAAGMEIITYSMLHRQGHMSPQPFRPPKPEDVATICYTSGTTGTPKGAVLSHANF 612 PA H + P + +A + YTSGTTG PKG H N Sbjct: 459 SSKFPA------------HNLDDL------PLTSQQLAYVTYTSGTTGFPKGIFKQHTNV 500 Query: 613 IANV 624 + ++ Sbjct: 501 VNSI 504 Score = 34.3 bits (77), Expect = 0.31 Identities = 16/33 (48%), Positives = 20/33 (60%) Frame = +1 Query: 505 SPQPFRPPKPEDVATICYTSGTTGTPKGAVLSH 603 +P P + D+A I YTSGTTG PKG + H Sbjct: 1556 NPSPLS--RSTDLAYIIYTSGTTGRPKGVTVEH 1586
>LGRD_BREPA (Q70LM4) Linear gramicidin synthetase subunit D [Includes:| ATP-dependent tryptophan adenylase (TrpA) (Tryptophan activase); ATP-dependent D-leucine adenylase (D-LeuA) (D-Leucine activase); Leucine racemase [ATP-hydrolyzing] (EC 5.1.1.-); ATP-d Length = 5085 Score = 40.8 bits (94), Expect = 0.003 Identities = 36/166 (21%), Positives = 64/166 (38%) Frame = +1 Query: 109 MTYGEAGTSRTAIGSGLICHGIPKGARVGLYFINRPEWTIVDNACSAYSYVSVPLYDTLG 288 +TYG+ + L G+ +G+ VG+ E I A +P+ Sbjct: 1543 LTYGQLEAKANQLAHYLQKQGVGRGSLVGICVERSVEMVIGQLAIMKAGAAYIPMDPAYP 1602 Query: 289 PDAVQFIVNHASVEAIFCVPQTLSTLLSFITQMPCVRLIVVVGGIDENMPSSPAAAGMEI 468 + + F+++ AS+ + + L + +++ C+ E + P AA + Sbjct: 1603 KERLAFMMHDASMAIVLTQAKLRQKLPADTSRLICL------DADWETIAQEPTAALVNT 1656 Query: 469 ITYSMLHRQGHMSPQPFRPPKPEDVATICYTSGTTGTPKGAVLSHA 606 S D+A + YTSG+TGTPKG + HA Sbjct: 1657 TAAS-------------------DLAYVIYTSGSTGTPKGVEIEHA 1683 Score = 35.0 bits (79), Expect = 0.18 Identities = 36/170 (21%), Positives = 58/170 (34%), Gaps = 1/170 (0%) Frame = +1 Query: 109 MTYGEAGTSRTAIGSGLICHGIPKGARVGLYFINRPEWTIVDNACSAYSYVSVPLYDTLG 288 +TYGE + L G+ VG+ E I A VP+ Sbjct: 4125 VTYGELNRQANQLAHYLRKQGVGPEVLVGICAERTVEMMIGLLAILKAGGAYVPIDPAYP 4184 Query: 289 PDAVQFIVNHASVEAIFCVPQTLSTLLSFITQMPCV-RLIVVVGGIDENMPSSPAAAGME 465 + + +I+ H+ + + L TL ++ C+ R V E P A + Sbjct: 4185 AERIAYIIGHSQIPVLLTQEHLLPTLPEHQAKVICLDRDWATVAVESEENPGKLATS--- 4241 Query: 466 IITYSMLHRQGHMSPQPFRPPKPEDVATICYTSGTTGTPKGAVLSHANFI 615 +++ + YTSG+TG PKG L H + I Sbjct: 4242 -----------------------DNLIYVIYTSGSTGNPKGVALEHRSVI 4268 Score = 32.0 bits (71), Expect = 1.6 Identities = 12/27 (44%), Positives = 20/27 (74%) Frame = +1 Query: 535 EDVATICYTSGTTGTPKGAVLSHANFI 615 +++A + YTSG+TG PKG ++ H + I Sbjct: 604 QNLAYVIYTSGSTGLPKGVMIEHHSAI 630 Score = 31.6 bits (70), Expect = 2.0 Identities = 12/22 (54%), Positives = 16/22 (72%) Frame = +1 Query: 538 DVATICYTSGTTGTPKGAVLSH 603 ++A + YTSGTTG PKG + H Sbjct: 3189 NLAYVIYTSGTTGLPKGVAVEH 3210
>ACSA_SCHPO (P78773) Probable acetyl-coenzyme A synthetase (EC 6.2.1.1)| (Acetate--CoA ligase) (Acyl-activating enzyme) Length = 662 Score = 40.8 bits (94), Expect = 0.003 Identities = 38/184 (20%), Positives = 72/184 (39%), Gaps = 9/184 (4%) Frame = +1 Query: 103 KWMTYGEAGTSRTAIGSGLICHGIPKGARVGLYFINRPEWTIVDNACSAYSYVSVPLYDT 282 +++TY E S + L G+ G RV +Y PE I A + ++ Sbjct: 116 RYITYRELLASVSQCAGALQSMGVGMGDRVAIYMPMIPETIIAMLAIVRLGAIHSVIFAG 175 Query: 283 LGPDAVQFIVNHASVEAIFCVPQT---------LSTLLSFITQMPCVRLIVVVGGIDENM 435 ++V VN + + I ++ + +T+ P ++ ++V E Sbjct: 176 FSAESVADRVNDSECKVIITADESHRGGKRIPLKGVVNKALTECPTIKKVLVFQRSAE-- 233 Query: 436 PSSPAAAGMEIITYSMLHRQGHMSPQPFRPPKPEDVATICYTSGTTGTPKGAVLSHANFI 615 P++ G ++ + ++ + P PE + YTSG+TG PKG V ++ Sbjct: 234 PTASMVEGRDVWWHDIIPKFPRYCPPAV--VNPEHPLFLLYTSGSTGKPKGVVHCTGGYL 291 Query: 616 ANVA 627 A Sbjct: 292 LGAA 295
>AAS_SALTY (Q8ZMA4) AAS bifunctional protein [Includes:| 2-acylglycerophosphoethanolamine acyltransferase (EC 2.3.1.40) (Acyl-[acyl-carrier-protein]--phospholipid O-acyltransferase) (2-acyl-GPE acyltransferase); Acyl-[acyl-carrier-protein] synthetase (EC 6 Length = 719 Score = 40.8 bits (94), Expect = 0.003 Identities = 18/32 (56%), Positives = 23/32 (71%) Frame = +1 Query: 529 KPEDVATICYTSGTTGTPKGAVLSHANFIANV 624 +PED A I +TSG+ G PKG V SH + +ANV Sbjct: 363 QPEDAAIILFTSGSEGHPKGVVHSHKSILANV 394
>AAS_SALTI (Q8Z406) AAS bifunctional protein [Includes:| 2-acylglycerophosphoethanolamine acyltransferase (EC 2.3.1.40) (Acyl-[acyl-carrier-protein]--phospholipid O-acyltransferase) (2-acyl-GPE acyltransferase); Acyl-[acyl-carrier-protein] synthetase (EC 6 Length = 719 Score = 40.8 bits (94), Expect = 0.003 Identities = 18/32 (56%), Positives = 23/32 (71%) Frame = +1 Query: 529 KPEDVATICYTSGTTGTPKGAVLSHANFIANV 624 +PED A I +TSG+ G PKG V SH + +ANV Sbjct: 363 QPEDAAIILFTSGSEGHPKGVVHSHKSILANV 394
>AAS_SALPA (Q5PEN7) AAS bifunctional protein [Includes:| 2-acylglycerophosphoethanolamine acyltransferase (EC 2.3.1.40) (Acyl-[acyl-carrier-protein]--phospholipid O-acyltransferase) (2-acyl-GPE acyltransferase); Acyl-[acyl-carrier-protein] synthetase (EC 6 Length = 719 Score = 40.8 bits (94), Expect = 0.003 Identities = 18/32 (56%), Positives = 23/32 (71%) Frame = +1 Query: 529 KPEDVATICYTSGTTGTPKGAVLSHANFIANV 624 +PED A I +TSG+ G PKG V SH + +ANV Sbjct: 363 QPEDAAIILFTSGSEGHPKGVVHSHKSILANV 394
>AAS_ECOL6 (Q8FEA6) AAS bifunctional protein [Includes:| 2-acylglycerophosphoethanolamine acyltransferase (EC 2.3.1.40) (Acyl-[acyl-carrier-protein]--phospholipid O-acyltransferase) (2-acyl-GPE acyltransferase); Acyl-[acyl-carrier-protein] synthetase (EC 6 Length = 719 Score = 40.8 bits (94), Expect = 0.003 Identities = 39/151 (25%), Positives = 62/151 (41%), Gaps = 2/151 (1%) Frame = +1 Query: 178 KGARVGLYFINRPEWTIVDNACSAYSYVSVPLYDTLGPDAVQFIVNHASVEAIFCVPQTL 357 +G R+GL N V A + + T G + + A ++ IF Q L Sbjct: 254 EGERIGLMLPNAGISAAVIFGAIARRRIPAMMNYTAGVKGLTSAITAAEIKTIFTSRQFL 313 Query: 358 ST--LLSFITQMPCVRLIVVVGGIDENMPSSPAAAGMEIITYSMLHRQGHMSPQPFRPPK 531 L Q+ VR + +++ A + I + ++ R + QP Sbjct: 314 DKGKLWHLPEQLTQVRWVY----LEDLKADVTTADKVWIFAHLLMPRLAQLKQQP----- 364 Query: 532 PEDVATICYTSGTTGTPKGAVLSHANFIANV 624 E+ A I +TSG+ G PKG V SH + +ANV Sbjct: 365 -EEEALILFTSGSEGHPKGVVHSHKSILANV 394
>4CL1_ARATH (Q42524) 4-coumarate--CoA ligase 1 (EC 6.2.1.12) (4CL 1) (At4CL1)| (4-coumaroyl-CoA synthase 1) Length = 561 Score = 40.8 bits (94), Expect = 0.003 Identities = 16/32 (50%), Positives = 23/32 (71%) Frame = +1 Query: 532 PEDVATICYTSGTTGTPKGAVLSHANFIANVA 627 P+DV + Y+SGTTG PKG +L+H + +VA Sbjct: 201 PDDVVALPYSSGTTGLPKGVMLTHKGLVTSVA 232
>4CL2_ARATH (Q9S725) 4-coumarate--CoA ligase 2 (EC 6.2.1.12) (4CL 2) (At4Cl2)| (4-coumaroyl-CoA synthase 2) Length = 556 Score = 40.4 bits (93), Expect = 0.004 Identities = 16/32 (50%), Positives = 23/32 (71%) Frame = +1 Query: 532 PEDVATICYTSGTTGTPKGAVLSHANFIANVA 627 PEDV + ++SGTTG PKG +L+H + +VA Sbjct: 194 PEDVVALPFSSGTTGLPKGVMLTHKGLVTSVA 225
>LCFA_SALTY (P63521) Long-chain-fatty-acid--CoA ligase (EC 6.2.1.3) (Long-chain| acyl-CoA synthetase) Length = 561 Score = 40.4 bits (93), Expect = 0.004 Identities = 17/30 (56%), Positives = 23/30 (76%) Frame = +1 Query: 535 EDVATICYTSGTTGTPKGAVLSHANFIANV 624 ED+A + YT GTTG KGA+L+H N +AN+ Sbjct: 206 EDLAFLQYTGGTTGVAKGAMLTHRNMLANL 235
>LCFA_SALTI (P63522) Long-chain-fatty-acid--CoA ligase (EC 6.2.1.3) (Long-chain| acyl-CoA synthetase) Length = 561 Score = 40.4 bits (93), Expect = 0.004 Identities = 17/30 (56%), Positives = 23/30 (76%) Frame = +1 Query: 535 EDVATICYTSGTTGTPKGAVLSHANFIANV 624 ED+A + YT GTTG KGA+L+H N +AN+ Sbjct: 206 EDLAFLQYTGGTTGVAKGAMLTHRNMLANL 235
>SRFAA_BACSU (P27206) Surfactin synthetase subunit 1| Length = 3588 Score = 40.4 bits (93), Expect = 0.004 Identities = 16/28 (57%), Positives = 22/28 (78%) Frame = +1 Query: 541 VATICYTSGTTGTPKGAVLSHANFIANV 624 +A + YTSGTTGTPKG +++HAN + V Sbjct: 1648 MANLTYTSGTTGTPKGNIVTHANILRTV 1675 Score = 33.1 bits (74), Expect = 0.70 Identities = 13/23 (56%), Positives = 18/23 (78%) Frame = +1 Query: 535 EDVATICYTSGTTGTPKGAVLSH 603 E++A + YTSGTTG PKG ++ H Sbjct: 2692 ENLAYMIYTSGTTGQPKGVMVEH 2714 Score = 32.7 bits (73), Expect = 0.91 Identities = 13/22 (59%), Positives = 17/22 (77%) Frame = +1 Query: 538 DVATICYTSGTTGTPKGAVLSH 603 ++A I YTSGTTG PKG ++ H Sbjct: 600 NLAYIIYTSGTTGRPKGVMIEH 621
>PPS1_BACSU (P39845) Peptide synthetase 1| Length = 2561 Score = 40.4 bits (93), Expect = 0.004 Identities = 16/29 (55%), Positives = 21/29 (72%) Frame = +1 Query: 526 PKPEDVATICYTSGTTGTPKGAVLSHANF 612 P PE+ I YTSGTTG PKG ++++ NF Sbjct: 1638 PAPEEPVYIIYTSGTTGAPKGVIVTYQNF 1666 Score = 33.9 bits (76), Expect = 0.41 Identities = 14/38 (36%), Positives = 21/38 (55%) Frame = +1 Query: 517 FRPPKPEDVATICYTSGTTGTPKGAVLSHANFIANVAG 630 F P +A + YTSG+TG PKG + H ++ + G Sbjct: 592 FTPADGGSLAYVIYTSGSTGQPKGVAVEHRQAVSFLTG 629
>ACSA_NEUCR (P16929) Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA| ligase) (Acyl-activating enzyme) Length = 667 Score = 40.4 bits (93), Expect = 0.004 Identities = 42/189 (22%), Positives = 74/189 (39%), Gaps = 11/189 (5%) Frame = +1 Query: 94 GDYKWMTYGEAGTSRTAIGSGLICHGIPKGARVGLYFINRPEWTIVDNACSAYSYVSVPL 273 G + +TYGE + + L G+ KG V +Y PE + AC+ + + Sbjct: 121 GQGRNVTYGELLREVSKLAHVLTNLGVRKGDTVAIYLPMIPEAIVAMLACTRIGAIHSVV 180 Query: 274 YDTLGPDAVQFIVNHASVEAIFCVPQ---------TLSTLLSFITQMPCVRLIVVVGGID 426 + D+++ V A + + + T + + Q P VR ++V Sbjct: 181 FAGFSSDSLRDRVVDAQSKVVITTDEGKRGGKLIGTKKIVDEALQQCPDVRNVLVYKRTG 240 Query: 427 ENMPSSPAAAGMEIITYSMLHRQGHMSPQPFRPPK--PEDVATICYTSGTTGTPKGAVLS 600 ++ +P G ++ H + P + P ED + YTSG+TG PKG S Sbjct: 241 ADISMTP---GRDL----WWHEEVEKYPAYYTPVAMASEDPLFLLYTSGSTGKPKGVAHS 293 Query: 601 HANFIANVA 627 ++ A Sbjct: 294 TGGYLLGAA 302
>AAS_SHIFL (Q83JV7) AAS bifunctional protein [Includes:| 2-acylglycerophosphoethanolamine acyltransferase (EC 2.3.1.40) (Acyl-[acyl-carrier-protein]--phospholipid O-acyltransferase) (2-acyl-GPE acyltransferase); Acyl-[acyl-carrier-protein] synthetase (EC 6 Length = 719 Score = 40.4 bits (93), Expect = 0.004 Identities = 39/151 (25%), Positives = 62/151 (41%), Gaps = 2/151 (1%) Frame = +1 Query: 178 KGARVGLYFINRPEWTIVDNACSAYSYVSVPLYDTLGPDAVQFIVNHASVEAIFCVPQTL 357 +G R+GL N V A + + T G + + A ++ IF Q L Sbjct: 254 EGERIGLMLPNAGISAAVIFGAIARRRIPAMMNYTAGVKGLTSAITAAEIKTIFTSRQFL 313 Query: 358 ST--LLSFITQMPCVRLIVVVGGIDENMPSSPAAAGMEIITYSMLHRQGHMSPQPFRPPK 531 L Q+ VR + +++ A + I + ++ R + QP Sbjct: 314 DKGKLWHLPEQLTQVRWVY----LEDLKADVTTADKVWIFAHLLMPRLAQVKQQP----- 364 Query: 532 PEDVATICYTSGTTGTPKGAVLSHANFIANV 624 E+ A I +TSG+ G PKG V SH + +ANV Sbjct: 365 -EEEALILFTSGSEGHPKGVVHSHKSILANV 394
>AAS_ECO57 (Q8X6J8) AAS bifunctional protein [Includes:| 2-acylglycerophosphoethanolamine acyltransferase (EC 2.3.1.40) (Acyl-[acyl-carrier-protein]--phospholipid O-acyltransferase) (2-acyl-GPE acyltransferase); Acyl-[acyl-carrier-protein] synthetase (EC 6 Length = 719 Score = 40.4 bits (93), Expect = 0.004 Identities = 39/151 (25%), Positives = 62/151 (41%), Gaps = 2/151 (1%) Frame = +1 Query: 178 KGARVGLYFINRPEWTIVDNACSAYSYVSVPLYDTLGPDAVQFIVNHASVEAIFCVPQTL 357 +G R+GL N V A + + T G + + A ++ IF Q L Sbjct: 254 EGERIGLMLPNAGISAAVIFGAIARRRIPAMMNYTAGVKGLTSAITAAEIKTIFTSRQFL 313 Query: 358 ST--LLSFITQMPCVRLIVVVGGIDENMPSSPAAAGMEIITYSMLHRQGHMSPQPFRPPK 531 L Q+ VR + +++ A + I + ++ R + QP Sbjct: 314 DKGKLWHLPEQLTQVRWVY----LEDLKADVTTADKVWIFAHLLMPRLAQVKQQP----- 364 Query: 532 PEDVATICYTSGTTGTPKGAVLSHANFIANV 624 E+ A I +TSG+ G PKG V SH + +ANV Sbjct: 365 -EEEALILFTSGSEGHPKGVVHSHKSILANV 394
>CAIC_SALTY (Q8ZRX4) Probable crotonobetaine/carnitine-CoA ligase (EC 6.2.1.-)| Length = 517 Score = 40.4 bits (93), Expect = 0.004 Identities = 40/149 (26%), Positives = 61/149 (40%), Gaps = 2/149 (1%) Frame = +1 Query: 169 GIPKGARVGLYFINRPEWTIVDNACSAYSYVSVPLYDTLGPDAVQFIVNHASVEAIFCVP 348 GI KG RV L+ N PE+ + + VP+ L + +I+ ++ V + Sbjct: 58 GIRKGDRVALHLDNCPEFIFCWFGLAKIGAIMVPINARLLGEESAWILQNSQVSLLVTSA 117 Query: 349 QTLSTLLSFITQMPCVRL--IVVVGGIDENMPSSPAAAGMEIITYSMLHRQGHMSPQPFR 522 Q + I Q L I ++G PA G+ T + + P Sbjct: 118 Q-FYPMYREIRQDNSTPLNHICLIG------EQLPADDGVSHFTQLQARQSATLCYTPVL 170 Query: 523 PPKPEDVATICYTSGTTGTPKGAVLSHAN 609 +D A I +TSGTT PKG V++H N Sbjct: 171 --STDDTAEILFTSGTTSRPKGVVITHYN 197
>CAIC_SALPA (Q5PIL0) Probable crotonobetaine/carnitine-CoA ligase (EC 6.2.1.-)| Length = 517 Score = 40.4 bits (93), Expect = 0.004 Identities = 39/149 (26%), Positives = 62/149 (41%), Gaps = 2/149 (1%) Frame = +1 Query: 169 GIPKGARVGLYFINRPEWTIVDNACSAYSYVSVPLYDTLGPDAVQFIVNHASVEAIFCVP 348 GI KG RV L+ N PE+ + + VP+ L + +I+ ++ V + Sbjct: 58 GIRKGDRVALHLDNCPEFIFCWFGLAKIGAIMVPINARLLGEESAWILQNSQVSLLVTSA 117 Query: 349 QTLSTLLSFITQMPCVRL--IVVVGGIDENMPSSPAAAGMEIITYSMLHRQGHMSPQPFR 522 Q + I Q L I ++G PA G+ + + + + P Sbjct: 118 Q-FYPMYREIRQGNSTPLNHICLIG------EQLPADDGVSLFSQLQARQSATLCYTPAL 170 Query: 523 PPKPEDVATICYTSGTTGTPKGAVLSHAN 609 +D A I +TSGTT PKG V++H N Sbjct: 171 --STDDAAEILFTSGTTSRPKGVVITHYN 197
>MENE_BACCR (Q816I1) 2-succinylbenzoate--CoA ligase (EC 6.2.1.26) (OSB-CoA| synthetase) (o-succinylbenzoyl-CoA synthetase) Length = 482 Score = 40.0 bits (92), Expect = 0.006 Identities = 17/32 (53%), Positives = 22/32 (68%) Frame = +1 Query: 535 EDVATICYTSGTTGTPKGAVLSHANFIANVAG 630 E+ TI YTSGTTG PKG +L++ N A+ G Sbjct: 140 EEAMTIIYTSGTTGKPKGVILTYGNHWASAVG 171
>MENE_BACC1 (Q72YK9) 2-succinylbenzoate--CoA ligase (EC 6.2.1.26) (OSB-CoA| synthetase) (o-succinylbenzoyl-CoA synthetase) Length = 481 Score = 40.0 bits (92), Expect = 0.006 Identities = 17/32 (53%), Positives = 22/32 (68%) Frame = +1 Query: 535 EDVATICYTSGTTGTPKGAVLSHANFIANVAG 630 E+ TI YTSGTTG PKG +L++ N A+ G Sbjct: 139 EEAMTIIYTSGTTGKPKGVILTYGNHWASAVG 170
>CAIC_SHIFL (Q83MG9) Probable crotonobetaine/carnitine-CoA ligase (EC 6.2.1.-)| Length = 522 Score = 40.0 bits (92), Expect = 0.006 Identities = 38/151 (25%), Positives = 62/151 (41%), Gaps = 4/151 (2%) Frame = +1 Query: 169 GIPKGARVGLYFINRPEWTIVDNACSAYSYVSVPLYDTLGPDAVQFIVNHAS----VEAI 336 GI KG +V L+ N PE+ + + VP+ L + ++I+ ++ V + Sbjct: 63 GIRKGNKVALHLDNCPEFIFCWFGLAKIGAIMVPINARLLREESEWILQNSQACLLVTSA 122 Query: 337 FCVPQTLSTLLSFITQMPCVRLIVVVGGIDENMPSSPAAAGMEIITYSMLHRQGHMSPQP 516 P TQ+ + L V D+ + S ++ L Q + Sbjct: 123 QFYPMYQQIQQEDATQLRHICLTDVALPADDGVSS-----------FTQLKNQQPATLCY 171 Query: 517 FRPPKPEDVATICYTSGTTGTPKGAVLSHAN 609 P +D A I +TSGTT PKG V++H N Sbjct: 172 APPLSTDDTAEILFTSGTTSRPKGVVITHYN 202
>ACSA_EMENI (P16928) Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA| ligase) (Acyl-activating enzyme) Length = 670 Score = 40.0 bits (92), Expect = 0.006 Identities = 44/184 (23%), Positives = 71/184 (38%), Gaps = 11/184 (5%) Frame = +1 Query: 109 MTYGEAGTSRTAIGSGLICHGIPKGARVGLYFINRPEWTIVDNACSAYSYVSVPLYDTLG 288 +TYGE + + L G+ KG V +Y PE I ACS V ++ Sbjct: 128 ITYGELLREVSRVAWVLKQRGVKKGDTVAIYLPMIPEAIIAFLACSRIGAVHSVVFAGFS 187 Query: 289 PDAVQFIVNHASVEAIFCVPQ---------TLSTLLSFITQMPCVRLIVVVGGIDENMPS 441 D+++ V A + + + T + + Q P V ++V +P Sbjct: 188 SDSLRDRVLDAGSKVVITTDEGKRGGKVIGTKRIVDEGLKQCPDVSTVLVYKRTGAEVPW 247 Query: 442 SPAAAGMEIITYSMLHRQGHMSPQPFRPPK--PEDVATICYTSGTTGTPKGAVLSHANFI 615 + G +I H + P P ED + YTSG+TG PKG + + A ++ Sbjct: 248 TE---GRDI----WWHEEVEKYPAYIAPDSVNSEDPLFLLYTSGSTGKPKGVMHTTAGYL 300 Query: 616 ANVA 627 A Sbjct: 301 LGAA 304
>ORA_PLAFN (P16405) Octapeptide-repeat antigen (ORA) (Fragment)| Length = 701 Score = 39.7 bits (91), Expect = 0.007 Identities = 35/194 (18%), Positives = 70/194 (36%), Gaps = 49/194 (25%) Frame = +1 Query: 190 VGLYFINRPEWTIVDNACSAYSYVSVPLYDTLGPDAVQFIVNHASVEAIFCVPQTLSTLL 369 +GLY N W I D AC ++ ++ D + I+N+ +E + + LL Sbjct: 35 LGLYGNNSTNWLITDCACMISGVTTLVMHSKFSIDIIIDILNNTKLEWLCLDLDLVEGLL 94 Query: 370 SFITQMPCVRLIVVVGGIDE---------------------------------------- 429 ++P ++ ++++ + + Sbjct: 95 CRKNELPYLKKLIILDNLTKRSEMKIENEEKSNGSRKSSNKQKYNESDKREDISLCALEC 154 Query: 430 ---------NMPSSPAAAGMEIITYSMLHRQGHMSPQPFRPPKPEDVATICYTSGTTGTP 582 ++ G+ II + + + ++ + P +A+I YTSGT+G P Sbjct: 155 DKEKIEKINSLKEKAKTLGLSIIVFDNM-TENKIANVTVQNEDPNFIASIVYTSGTSGKP 213 Query: 583 KGAVLSHANFIANV 624 KG +LS+ N V Sbjct: 214 KGVMLSNRNLYNGV 227
>CAIC_PROSL (Q8GB18) Probable crotonobetaine/carnitine-CoA ligase (EC 6.2.1.-)| Length = 518 Score = 39.7 bits (91), Expect = 0.007 Identities = 39/174 (22%), Positives = 64/174 (36%), Gaps = 2/174 (1%) Frame = +1 Query: 94 GDYKWMTYGEAGTSRTAIGSGLICHGIPKGARVGLYFINRPEWTIVDNACSAYSYVSVPL 273 G + +Y E + GI KG V L+ N PE+ + V VP+ Sbjct: 33 GKVRQFSYSELNEEINRAANLFHACGIKKGDHVALHLDNCPEFFFCWFGLAKIGAVMVPI 92 Query: 274 YDTLGPDAVQFIVNHASVEAIFCVPQTLSTLLSFI--TQMPCVRLIVVVGGIDENMPSSP 447 + +I+NH + + P +L ++ EN P Sbjct: 93 NARFMYEESAWIINHCQAHFVVTSDNFSPIYQPMLHDKHSPLTQLFLIT----ENC--LP 146 Query: 448 AAAGMEIITYSMLHRQGHMSPQPFRPPKPEDVATICYTSGTTGTPKGAVLSHAN 609 G ++ + + ++ P +D A I +TSGTT PKG V++H N Sbjct: 147 TEQG--VVDFLSEKAKHPVTLNHHTPLSVDDTAEILFTSGTTSQPKGVVITHYN 198
>HTS1_COCCA (Q01886) HC-toxin synthetase (EC 6.3.2.-) (HTS)| Length = 5218 Score = 39.7 bits (91), Expect = 0.007 Identities = 43/177 (24%), Positives = 69/177 (38%), Gaps = 5/177 (2%) Frame = +1 Query: 109 MTYGEAGTSRTAIGSGLICHGIPKGARVGLYFINRPEWTIVDNACSAYSYVSVPLYDTLG 288 +TY E + L+ GI G ++ + F + WTIV + L + Sbjct: 1847 LTYAELSDLSQRLSIHLVSLGIKVGTKIPICF-EKSMWTIVTILAVVQAGGVFVLLEPGH 1905 Query: 289 PDA-VQFIVNHASVEAIFCVPQT--LSTLLSFITQMPCVRLIVVVGGIDENMPSSPAAAG 459 P++ + I+ E + C P T + L + TQM IV + E + S P Sbjct: 1906 PESRLSGIIKQVQAELLLCSPATSRMGALQNISTQMGTEFKIVELE--PEFIRSLP---- 1959 Query: 460 MEIITYSMLHRQGHMSPQPFRPPKP--EDVATICYTSGTTGTPKGAVLSHANFIANV 624 + P+P P D + +TSG+TG PKGAV +H + + Sbjct: 1960 --------------LPPKPNHQPMVGLNDDLYVVFTSGSTGVPKGAVATHQAYATGI 2002 Score = 33.5 bits (75), Expect = 0.53 Identities = 13/25 (52%), Positives = 17/25 (68%) Frame = +1 Query: 529 KPEDVATICYTSGTTGTPKGAVLSH 603 +P A I +TSG+TG PKG V+ H Sbjct: 4272 RPNQAAYILFTSGSTGKPKGVVMEH 4296 Score = 32.7 bits (73), Expect = 0.91 Identities = 13/24 (54%), Positives = 16/24 (66%) Frame = +1 Query: 532 PEDVATICYTSGTTGTPKGAVLSH 603 P A + YTSGT+G PKG V+ H Sbjct: 3125 PSSPAYLLYTSGTSGKPKGVVMEH 3148
>BACB_BACLI (O68007) Bacitracin synthetase 2 (BA2) [Includes: ATP-dependent| lysine adenylase (LysA) (Lysine activase); ATP-dependent D-ornithine adenylase (D-OrnA) (D-ornithine activase); Ornithine racemase (EC 5.1.1.12)] Length = 2607 Score = 39.7 bits (91), Expect = 0.007 Identities = 16/28 (57%), Positives = 20/28 (71%) Frame = +1 Query: 532 PEDVATICYTSGTTGTPKGAVLSHANFI 615 P D+A + YTSGTTG PKG ++ H N I Sbjct: 1689 PGDLAYVIYTSGTTGNPKGVMVEHRNII 1716 Score = 34.7 bits (78), Expect = 0.24 Identities = 13/29 (44%), Positives = 20/29 (68%) Frame = +1 Query: 529 KPEDVATICYTSGTTGTPKGAVLSHANFI 615 K D+A + YTSG++G PKG + +H N + Sbjct: 655 KASDLAYVIYTSGSSGRPKGVMTTHRNVV 683
>AAS_ECOLI (P31119) AAS bifunctional protein [Includes:| 2-acylglycerophosphoethanolamine acyltransferase (EC 2.3.1.40) (Acyl-[acyl-carrier-protein]--phospholipid O-acyltransferase) (2-acyl-GPE acyltransferase); Acyl-[acyl-carrier-protein] synthetase (EC 6 Length = 719 Score = 39.7 bits (91), Expect = 0.007 Identities = 39/151 (25%), Positives = 62/151 (41%), Gaps = 2/151 (1%) Frame = +1 Query: 178 KGARVGLYFINRPEWTIVDNACSAYSYVSVPLYDTLGPDAVQFIVNHASVEAIFCVPQTL 357 +G R+GL N V A + + T G + + A ++ IF Q L Sbjct: 254 EGERIGLMLPNAGISAAVIFGAIARRRMPAMMNYTAGVKGLTSAITAAEIKTIFTSRQFL 313 Query: 358 ST--LLSFITQMPCVRLIVVVGGIDENMPSSPAAAGMEIITYSMLHRQGHMSPQPFRPPK 531 L Q+ VR + +++ A + I + ++ R + QP Sbjct: 314 DKGKLWHLPEQLTQVRWVY----LEDLKADVTTADKVWIFAHLLMPRLAQVKQQP----- 364 Query: 532 PEDVATICYTSGTTGTPKGAVLSHANFIANV 624 E+ A I +TSG+ G PKG V SH + +ANV Sbjct: 365 -EEEALILFTSGSEGHPKGVVHSHKSILANV 394
>ACSA_METSO (P27095) Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA| ligase) (Acyl-activating enzyme) Length = 672 Score = 39.7 bits (91), Expect = 0.007 Identities = 45/177 (25%), Positives = 66/177 (37%), Gaps = 11/177 (6%) Frame = +1 Query: 109 MTYGEAGTSRTAIGSGLICHGIPKGARVGLYFINRPEWTIVDNACSAYSYVSVPLYDTLG 288 +TYG+ +GL G+ KG RV +Y P+ I AC+ + ++ Sbjct: 134 ITYGDLYKEVNKFANGLKSLGLKKGDRVSIYMPMIPQLPIAMLACAKLGVSHIVVFSGFS 193 Query: 289 PDAVQFIVNHASVEAIFCV--------PQTLSTLLSFITQ-MPCVRLIVVV--GGIDENM 435 + H AI V P L P V I+V G+D +M Sbjct: 194 SKGLMDRAAHCGSRAIITVDGFYRRGKPVPLKPNADEAAGGAPSVEKIIVYKRAGVDVSM 253 Query: 436 PSSPAAAGMEIITYSMLHRQGHMSPQPFRPPKPEDVATICYTSGTTGTPKGAVLSHA 606 G ++ + ++ Q + PE I YTSGTTG PKG + HA Sbjct: 254 KE-----GRDVWWHDLVKGQSEECEPVW--VDPEHRLYILYTSGTTGKPKG--IEHA 301
>4CL1_ORYSA (P17814) 4-coumarate--CoA ligase 1 (EC 6.2.1.12) (4CL 1)| (4-coumaroyl-CoA synthase 1) Length = 564 Score = 39.3 bits (90), Expect = 0.010 Identities = 16/32 (50%), Positives = 23/32 (71%) Frame = +1 Query: 532 PEDVATICYTSGTTGTPKGAVLSHANFIANVA 627 P+DV + Y+SGTTG PKG +L+H + +VA Sbjct: 200 PDDVVALPYSSGTTGLPKGVMLTHRSLSTSVA 231
>4CL2_PETCR (P14913) 4-coumarate--CoA ligase 1 (EC 6.2.1.12) (4CL 1)| (4-coumaroyl-CoA synthase 1) Length = 544 Score = 39.3 bits (90), Expect = 0.010 Identities = 43/172 (25%), Positives = 69/172 (40%) Frame = +1 Query: 112 TYGEAGTSRTAIGSGLICHGIPKGARVGLYFINRPEWTIVDNACSAYSYVSVPLYDTLGP 291 TY + + SGL GI +G + L N PE+ ++++ + Sbjct: 55 TYSQVELLSRKVASGLNKLGIQQGDTIMLLLPNSPEYF--------FAFLGASYRGAIST 106 Query: 292 DAVQFIVNHASVEAIFCVPQTLSTLLSFITQMPCVRLIVVVGGIDENMPSSPAAAGMEII 471 A F S E I + +L+ L+ ITQ V + A + + Sbjct: 107 MANPFFT---SAEVIKQLKASLAKLI--ITQACYVDKVKDYAAEKNIQIICIDDAPQDCL 161 Query: 472 TYSMLHRQGHMSPQPFRPPKPEDVATICYTSGTTGTPKGAVLSHANFIANVA 627 +S L + S P +DV + Y+SGTTG PKG +L+H + +VA Sbjct: 162 HFSKL-MEADESEMPEVVIDSDDVVALPYSSGTTGLPKGVMLTHKGLVTSVA 212
>SRFAC_BACSU (Q08787) Surfactin synthetase subunit 3| Length = 1274 Score = 39.3 bits (90), Expect = 0.010 Identities = 17/26 (65%), Positives = 19/26 (73%) Frame = +1 Query: 532 PEDVATICYTSGTTGTPKGAVLSHAN 609 P D A I YTSGTTG PKG + +HAN Sbjct: 606 PNDPAYIMYTSGTTGKPKGNITTHAN 631
>PPS2_BACSU (P39846) Peptide synthetase 2| Length = 2560 Score = 39.3 bits (90), Expect = 0.010 Identities = 18/44 (40%), Positives = 27/44 (61%) Frame = +1 Query: 472 TYSMLHRQGHMSPQPFRPPKPEDVATICYTSGTTGTPKGAVLSH 603 T ++ H + + + P PP D+A + YTSGTTG PKG ++ H Sbjct: 588 TITIEHTESYQTEAPNMPPG--DLAYLIYTSGTTGRPKGVLVDH 629 Score = 35.4 bits (80), Expect = 0.14 Identities = 14/25 (56%), Positives = 18/25 (72%) Frame = +1 Query: 544 ATICYTSGTTGTPKGAVLSHANFIA 618 A + YTSGTTG PKG ++ H N I+ Sbjct: 1643 AYVIYTSGTTGQPKGVIVEHRNVIS 1667
>DLTA_LISIN (Q92D47) D-alanine--poly(phosphoribitol) ligase subunit 1 (EC| 6.1.1.13) (D-alanine-activating enzyme) (DAE) (D-alanine-D-alanyl carrier protein ligase) (DCL) Length = 510 Score = 39.3 bits (90), Expect = 0.010 Identities = 22/68 (32%), Positives = 32/68 (47%), Gaps = 4/68 (5%) Frame = +1 Query: 427 ENMPSSPAAAGMEIITYSML----HRQGHMSPQPFRPPKPEDVATICYTSGTTGTPKGAV 594 E +PS+ G ++T L + P P K +D I YTSG+TG PKG Sbjct: 109 EELPSNLTITGCPVLTQDQLMDALEKHFEEVPDPAECVKNDDNYYIIYTSGSTGNPKGVQ 168 Query: 595 LSHANFIA 618 +S N ++ Sbjct: 169 ISQNNLVS 176
>CAIC_ECO57 (Q8XA34) Probable crotonobetaine/carnitine-CoA ligase (EC 6.2.1.-)| Length = 522 Score = 38.9 bits (89), Expect = 0.013 Identities = 38/151 (25%), Positives = 61/151 (40%), Gaps = 4/151 (2%) Frame = +1 Query: 169 GIPKGARVGLYFINRPEWTIVDNACSAYSYVSVPLYDTLGPDAVQFIVNHAS----VEAI 336 GI KG +V L+ N PE+ + + VP+ L + +I+ ++ V + Sbjct: 63 GIRKGDKVALHLDNCPEFIFCWFGLAKIGAIMVPINARLLREESAWILQNSQACLLVTSA 122 Query: 337 FCVPQTLSTLLSFITQMPCVRLIVVVGGIDENMPSSPAAAGMEIITYSMLHRQGHMSPQP 516 P TQ+ + L V D+ + S ++ L Q + Sbjct: 123 QFYPMYQQIQQEDATQLRHICLTDVALPADDGVSS-----------FTQLKNQQPATLCY 171 Query: 517 FRPPKPEDVATICYTSGTTGTPKGAVLSHAN 609 P +D A I +TSGTT PKG V++H N Sbjct: 172 APPLSTDDTAEILFTSGTTSRPKGVVITHYN 202
>GRSA_BREBE (P0C062) Gramicidin S synthetase 1 (Gramicidin S synthetase I)| [Includes: ATP-dependent D-phenylalanine adenylase (D-PheA) (D-phenylalanine activase); Phenylalanine racemase [ATP-hydrolyzing] (EC 5.1.1.11)] Length = 1098 Score = 38.9 bits (89), Expect = 0.013 Identities = 16/27 (59%), Positives = 19/27 (70%) Frame = +1 Query: 523 PPKPEDVATICYTSGTTGTPKGAVLSH 603 P K D+A + YTSGTTG PKG +L H Sbjct: 178 PSKSTDLAYVIYTSGTTGNPKGTMLEH 204
>GRSA_ANEMI (P0C061) Gramicidin S synthetase 1 (Gramicidin S synthetase I)| [Includes: ATP-dependent D-phenylalanine adenylase (D-PheA) (D-phenylalanine activase); Phenylalanine racemase [ATP-hydrolyzing] (EC 5.1.1.11)] Length = 1098 Score = 38.9 bits (89), Expect = 0.013 Identities = 16/27 (59%), Positives = 19/27 (70%) Frame = +1 Query: 523 PPKPEDVATICYTSGTTGTPKGAVLSH 603 P K D+A + YTSGTTG PKG +L H Sbjct: 178 PSKSTDLAYVIYTSGTTGNPKGTMLEH 204
>MENE_BACCZ (Q632I5) 2-succinylbenzoate--CoA ligase (EC 6.2.1.26) (OSB-CoA| synthetase) (o-succinylbenzoyl-CoA synthetase) Length = 482 Score = 38.5 bits (88), Expect = 0.017 Identities = 16/32 (50%), Positives = 22/32 (68%) Frame = +1 Query: 535 EDVATICYTSGTTGTPKGAVLSHANFIANVAG 630 ++ TI YTSGTTG PKG +L++ N A+ G Sbjct: 140 KEAMTIIYTSGTTGKPKGVILTYGNHWASAVG 171
>BACA_BACLI (O68006) Bacitracin synthetase 1 (BA1) [Includes: ATP-dependent| isoleucine adenylase (IleA) (Isoleucine activase); ATP-dependent cysteine adenylase (CysA) (Cysteine activase); ATP-dependent leucine adenylase (LeuA) (Leucine activase); ATP-depe Length = 5255 Score = 38.5 bits (88), Expect = 0.017 Identities = 30/121 (24%), Positives = 50/121 (41%), Gaps = 14/121 (11%) Frame = +1 Query: 283 LGPDAVQFIVNHASVEAIFCV--------------PQTLSTLLSFITQMPCVRLIVVVGG 420 +GPD + I+ S+E I + P +S+I + V ++ G Sbjct: 3196 VGPDVIAGILTERSIEMIVGIMGILKAGGAYLPIDPAYPQERISYIVKDSDVSVLCAAGD 3255 Query: 421 IDENMPSSPAAAGMEIITYSMLHRQGHMSPQPFRPPKPEDVATICYTSGTTGTPKGAVLS 600 +D A +II + H+ KP+ +A + YTSG+TG PKG ++ Sbjct: 3256 VDPG-----EAYTGDIIRIDQTGQNDHVENLK-HDIKPQHLAYVIYTSGSTGKPKGVMIE 3309 Query: 601 H 603 H Sbjct: 3310 H 3310 Score = 36.6 bits (83), Expect = 0.063 Identities = 16/28 (57%), Positives = 19/28 (67%) Frame = +1 Query: 520 RPPKPEDVATICYTSGTTGTPKGAVLSH 603 R + D A I YTSG+TGTPKG V+ H Sbjct: 4799 RVNRSSDTAYIVYTSGSTGTPKGVVIPH 4826 Score = 35.0 bits (79), Expect = 0.18 Identities = 15/26 (57%), Positives = 18/26 (69%) Frame = +1 Query: 538 DVATICYTSGTTGTPKGAVLSHANFI 615 D A I YTSG+TGTPKG + H + I Sbjct: 178 DTAYIIYTSGSTGTPKGVITPHYSVI 203 Score = 34.3 bits (77), Expect = 0.31 Identities = 13/26 (50%), Positives = 19/26 (73%) Frame = +1 Query: 538 DVATICYTSGTTGTPKGAVLSHANFI 615 D+A + YTSG+TG PKG ++ H + I Sbjct: 2267 DLAYVIYTSGSTGKPKGVMIEHQSLI 2292 Score = 31.2 bits (69), Expect = 2.6 Identities = 11/23 (47%), Positives = 18/23 (78%) Frame = +1 Query: 535 EDVATICYTSGTTGTPKGAVLSH 603 +D+A + +TSG+TG PKG ++H Sbjct: 1215 DDMAYVIFTSGSTGKPKGVQITH 1237
>GRSB_ANEMI (P0C063) Gramicidin S synthetase 2 (Gramicidin S synthetase II)| [Includes: ATP-dependent proline adenylase (ProA) (Proline activase); ATP-dependent valine adenylase (ValA) (Valine activase); ATP-dependent ornithine adenylase (OrnA) (Ornithine Length = 4450 Score = 38.5 bits (88), Expect = 0.017 Identities = 17/33 (51%), Positives = 24/33 (72%) Frame = +1 Query: 529 KPEDVATICYTSGTTGTPKGAVLSHANFIANVA 627 +P +A I YTSGTTG PKG ++ H +++ NVA Sbjct: 2679 RPHYIAYIIYTSGTTGKPKGVMIEHQSYV-NVA 2710 Score = 38.1 bits (87), Expect = 0.022 Identities = 16/27 (59%), Positives = 19/27 (70%) Frame = +1 Query: 535 EDVATICYTSGTTGTPKGAVLSHANFI 615 ED+ I YTSGTTG PKG +L H N + Sbjct: 605 EDLFYIIYTSGTTGKPKGVMLEHKNIV 631 Score = 36.2 bits (82), Expect = 0.082 Identities = 15/26 (57%), Positives = 19/26 (73%) Frame = +1 Query: 538 DVATICYTSGTTGTPKGAVLSHANFI 615 D+A I YTSGTTG PKG ++ H + I Sbjct: 3729 DLAYIIYTSGTTGKPKGVMIEHQSII 3754 Score = 35.8 bits (81), Expect = 0.11 Identities = 15/26 (57%), Positives = 19/26 (73%) Frame = +1 Query: 538 DVATICYTSGTTGTPKGAVLSHANFI 615 D+A I YTSG+TG PKG ++ H N I Sbjct: 1646 DLAYIMYTSGSTGKPKGVMVEHRNVI 1671
>ACSA_VIBVY (Q7MGU3) Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA| ligase) (Acyl-activating enzyme) Length = 650 Score = 38.5 bits (88), Expect = 0.017 Identities = 40/189 (21%), Positives = 70/189 (37%), Gaps = 16/189 (8%) Frame = +1 Query: 97 DYKWMTYGEAGTSRTAIGSGLICHGIPKGARVGLYFINRPEWTIVDNACSAYSYVSVPLY 276 D K +TY E T + L G+ KG V LY PE + AC+ V ++ Sbjct: 104 DDKTLTYNELYTEVCRFSNALKEQGVRKGDVVCLYMPMVPEAAVAMLACTRIGAVHTIVF 163 Query: 277 DTLGPDAVQFIVNHASVEAIFCVPQTLSTLLSFITQMPCVRLIVVVGGIDENMPSSPAAA 456 P+A+ + + + + + + R + + +DE + + Sbjct: 164 GGFSPEALAGRIIDSDAKVVITADEGVRG----------GRAVPLKKNVDEALTNPEVKT 213 Query: 457 GMEIITYSML--------HR-----QGHMSPQPFRPP---KPEDVATICYTSGTTGTPKG 588 +++ + HR + PP K ED I YTSG+TG PKG Sbjct: 214 ISKVVVFKRTGGNIDWHEHRDVWWHEATAKVSDVCPPEEMKAEDPLFILYTSGSTGKPKG 273 Query: 589 AVLSHANFI 615 + + ++ Sbjct: 274 VLHTTGGYL 282
>ACSA_VIBVU (Q8DCZ9) Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA| ligase) (Acyl-activating enzyme) Length = 650 Score = 38.5 bits (88), Expect = 0.017 Identities = 40/189 (21%), Positives = 70/189 (37%), Gaps = 16/189 (8%) Frame = +1 Query: 97 DYKWMTYGEAGTSRTAIGSGLICHGIPKGARVGLYFINRPEWTIVDNACSAYSYVSVPLY 276 D K +TY E T + L G+ KG V LY PE + AC+ V ++ Sbjct: 104 DDKTLTYNELYTEVCRFSNALKEQGVRKGDVVCLYMPMVPEAAVAMLACTRIGAVHTIVF 163 Query: 277 DTLGPDAVQFIVNHASVEAIFCVPQTLSTLLSFITQMPCVRLIVVVGGIDENMPSSPAAA 456 P+A+ + + + + + + R + + +DE + + Sbjct: 164 GGFSPEALAGRIIDSDAKVVITADEGVRG----------GRAVPLKKNVDEALTNPEVKT 213 Query: 457 GMEIITYSML--------HR-----QGHMSPQPFRPP---KPEDVATICYTSGTTGTPKG 588 +++ + HR + PP K ED I YTSG+TG PKG Sbjct: 214 ISKVVVFKRTGGNIDWHEHRDVWWHEATAKVSDVCPPEEMKAEDPLFILYTSGSTGKPKG 273 Query: 589 AVLSHANFI 615 + + ++ Sbjct: 274 VLHTTGGYL 282
>MENE_BACSU (P23971) 2-succinylbenzoate--CoA ligase (EC 6.2.1.26) (OSB-CoA| synthetase) (o-succinylbenzoyl-CoA synthetase) Length = 486 Score = 38.5 bits (88), Expect = 0.017 Identities = 40/167 (23%), Positives = 60/167 (35%) Frame = +1 Query: 109 MTYGEAGTSRTAIGSGLICHGIPKGARVGLYFINRPEWTIVDNACSAYSYVSVPLYDTLG 288 +T+ E + + L H + KG + NR E +AC LG Sbjct: 29 VTFAELFAASKRMAEQLAAHSVRKGDTAAILLQNRAEMVYAVHACFL-----------LG 77 Query: 289 PDAVQFIVNHASVEAIFCVPQTLSTLLSFITQMPCVRLIVVVGGIDENMPSSPAAAGMEI 468 AV ++ E +F + + S L + +V ID + AA +EI Sbjct: 78 VKAVLLNTKLSTHERLFQLEDSGSGFLLTDSSFEKKEYEHIVQTIDVDELMKEAAEEIEI 137 Query: 469 ITYSMLHRQGHMSPQPFRPPKPEDVATICYTSGTTGTPKGAVLSHAN 609 Y + + AT+ YTSGTTG PKG + N Sbjct: 138 EAYMQM----------------DATATLMYTSGTTGKPKGVQQTFGN 168
>ACSA_AGRRH (Q9KWA3) Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA| ligase) (Acyl-activating enzyme) Length = 652 Score = 38.5 bits (88), Expect = 0.017 Identities = 45/182 (24%), Positives = 72/182 (39%), Gaps = 13/182 (7%) Frame = +1 Query: 109 MTYGEAGTSRTAIGSGLICHGIPKGARVGLYFINRPEWTIVDNACSAYSYVSVPLYDTLG 288 +TY E + + L HG+ KG RV +Y PE AC+ + ++ Sbjct: 106 ITYRELYEHVCRMANVLKKHGVKKGDRVTIYMPMVPEAAYAMLACARIGAIHSVVFGGFS 165 Query: 289 PDAVQF-IVNHASVEAIFC-------VPQTLSTLLSFITQMPCVRLIVVVGGIDENMPSS 444 P+A+ IV+ S I C P L + + ++V + S Sbjct: 166 PEALGGRIVDCQSTFVITCDEGLRGGKPVPLKANVDKAIDIAARGHVMVKNVLVIRRTGS 225 Query: 445 PA--AAGMEIITYSMLHRQGHMSPQPFRPPKP---EDVATICYTSGTTGTPKGAVLSHAN 609 P A G ++ H + + PP+P ED I YTSG+TG PKG + + Sbjct: 226 PLSWAPGRDL-----WHHEEAATVSADCPPEPMKAEDPLFILYTSGSTGKPKGVLHTTGG 280 Query: 610 FI 615 ++ Sbjct: 281 YL 282
>TYCB_BREPA (O30408) Tyrocidine synthetase 2 (Tyrocidine synthetase II)| [Includes: ATP-dependent proline adenylase (ProA) (Proline activase); ATP-dependent phenylalanine adenylase (PheA) (Phenylalanine activase); ATP-dependent D-phenylalanine adenylase (D Length = 3587 Score = 38.5 bits (88), Expect = 0.017 Identities = 18/31 (58%), Positives = 22/31 (70%) Frame = +1 Query: 532 PEDVATICYTSGTTGTPKGAVLSHANFIANV 624 P D+A I YTSGTTG PKG +L H +AN+ Sbjct: 2683 PSDLAYIIYTSGTTGKPKGVMLEHKG-VANL 2712 Score = 38.1 bits (87), Expect = 0.022 Identities = 16/27 (59%), Positives = 19/27 (70%) Frame = +1 Query: 529 KPEDVATICYTSGTTGTPKGAVLSHAN 609 +P D+ I YTSGTTG PKG +L H N Sbjct: 605 QPHDLFYIIYTSGTTGQPKGVMLEHRN 631 Score = 37.7 bits (86), Expect = 0.028 Identities = 28/81 (34%), Positives = 39/81 (48%), Gaps = 3/81 (3%) Frame = +1 Query: 391 CVRLIVVVGGIDENMPSSPAAAGMEIITYSMLHRQGHMSPQP--FRP-PKPEDVATICYT 561 C RL++ + E M A +E + L +G SPQ P D+A I YT Sbjct: 1603 CRRLVLTQQQLAEKM-----TANVECL---YLDEEGSYSPQTENIEPIHTAADLAYIIYT 1654 Query: 562 SGTTGTPKGAVLSHANFIANV 624 SGTTG PKG ++ H + +V Sbjct: 1655 SGTTGRPKGVMVEHRGIVNSV 1675
>CAIC_ECOLI (P31552) Probable crotonobetaine/carnitine-CoA ligase (EC 6.2.1.-)| Length = 522 Score = 38.5 bits (88), Expect = 0.017 Identities = 38/151 (25%), Positives = 61/151 (40%), Gaps = 4/151 (2%) Frame = +1 Query: 169 GIPKGARVGLYFINRPEWTIVDNACSAYSYVSVPLYDTLGPDAVQFIVNHAS----VEAI 336 GI KG +V L+ N PE+ + + VP+ L + +I+ ++ V + Sbjct: 63 GIRKGDKVALHLDNCPEFIFCWFGLAKIGAIMVPINARLLCEESAWILQNSQACLLVTSA 122 Query: 337 FCVPQTLSTLLSFITQMPCVRLIVVVGGIDENMPSSPAAAGMEIITYSMLHRQGHMSPQP 516 P TQ+ + L V D+ + S ++ L Q + Sbjct: 123 QFYPMYQQIQQEDATQLRHICLTDVALPADDGVSS-----------FTQLKNQQPATLCY 171 Query: 517 FRPPKPEDVATICYTSGTTGTPKGAVLSHAN 609 P +D A I +TSGTT PKG V++H N Sbjct: 172 APPLSTDDTAEILFTSGTTSRPKGVVITHYN 202
>ACSA2_RHIME (Q92KX2) Acetyl-coenzyme A synthetase 2 (EC 6.2.1.1) (Acetate--CoA| ligase 2) (Acyl-activating enzyme 2) Length = 649 Score = 38.5 bits (88), Expect = 0.017 Identities = 44/187 (23%), Positives = 73/187 (39%), Gaps = 16/187 (8%) Frame = +1 Query: 103 KWMTYGEAGTSRTAIGSGLICHGIPKGARVGLYFINRPEWTIVDNACSAYSYVSVPLYDT 282 K +TY E + + L G+ KG RV +Y PE AC+ + ++ Sbjct: 104 KKITYNELYDKVCRLANVLKEQGVKKGDRVTIYMPMIPEAAYAMLACARIGAIHSVVFGG 163 Query: 283 LGPDAVQF-IVNHASVEAIFC-----------VPQTLSTLLSFIT-QMPCVRLIVVVGGI 423 P+A+ IV+ S I C + + T + Q V ++VV Sbjct: 164 FSPEALAGRIVDCESTFVITCDEGVRGGKPVALKENTDTAIDIAARQHVTVSKVLVVRRT 223 Query: 424 DENMPSSPAAAGMEIITYSMLHRQGHMSPQPFRPPKP---EDVATICYTSGTTGTPKGAV 594 + +P + + Q + +P PP+ ED I YTSG+TG PKG + Sbjct: 224 GGKVGWAPGR--------DLWYHQETAAAEPHCPPEKMNAEDPLFILYTSGSTGKPKGVL 275 Query: 595 LSHANFI 615 + ++ Sbjct: 276 HTTGGYL 282
>CAIC_SALTI (Q8Z9L4) Probable crotonobetaine/carnitine-CoA ligase (EC 6.2.1.-)| Length = 517 Score = 38.5 bits (88), Expect = 0.017 Identities = 39/149 (26%), Positives = 61/149 (40%), Gaps = 2/149 (1%) Frame = +1 Query: 169 GIPKGARVGLYFINRPEWTIVDNACSAYSYVSVPLYDTLGPDAVQFIVNHASVEAIFCVP 348 GI KG RV L+ N PE+ + + VP+ L + +I+ ++ V + Sbjct: 58 GIRKGDRVALHLDNCPEFIFCWFGLAKIGAIMVPINARLLGEESAWILQNSQVSLLVTSA 117 Query: 349 QTLSTLLSFITQMPCVRL--IVVVGGIDENMPSSPAAAGMEIITYSMLHRQGHMSPQPFR 522 Q + I Q L I ++G PA G+ + + + P Sbjct: 118 Q-FYPMYREIRQDNSTPLNHICLIG------EQLPADDGVSHFSQLQARQSATLCYTPAL 170 Query: 523 PPKPEDVATICYTSGTTGTPKGAVLSHAN 609 +D A I +TSGTT PKG V++H N Sbjct: 171 --STDDTAEILFTSGTTSRPKGVVITHYN 197
>CAIC_SALCH (Q57TJ0) Probable crotonobetaine/carnitine-CoA ligase (EC 6.2.1.-)| Length = 517 Score = 38.5 bits (88), Expect = 0.017 Identities = 40/157 (25%), Positives = 64/157 (40%), Gaps = 10/157 (6%) Frame = +1 Query: 169 GIPKGARVGLYFINRPEWTIVDNACSAYSYVSVPLYDTLGPDAVQFIVNHASVEAIFC-- 342 GI KG RV L+ N PE+ + + VP+ L + +I+ ++ V + Sbjct: 58 GIRKGDRVALHLDNCPEFIFCWFGLAKIGAIMVPINARLLGEESAWILQNSQVSLLVTSV 117 Query: 343 --------VPQTLSTLLSFITQMPCVRLIVVVGGIDENMPSSPAAAGMEIITYSMLHRQG 498 + Q ST L+ I C+ I E +P+ + +S L + Sbjct: 118 QFYPMYREIRQDNSTPLNHI----CL--------IGEQLPADDGVSH-----FSQLQARQ 160 Query: 499 HMSPQPFRPPKPEDVATICYTSGTTGTPKGAVLSHAN 609 + +D A I +TSGTT PKG V++H N Sbjct: 161 SATLCYTPALSTDDTAEILFTSGTTSRPKGVVITHYN 197
>MENE_BACHK (Q6HC29) 2-succinylbenzoate--CoA ligase (EC 6.2.1.26) (OSB-CoA| synthetase) (o-succinylbenzoyl-CoA synthetase) Length = 482 Score = 38.1 bits (87), Expect = 0.022 Identities = 16/31 (51%), Positives = 21/31 (67%) Frame = +1 Query: 538 DVATICYTSGTTGTPKGAVLSHANFIANVAG 630 + TI YTSGTTG PKG +L++ N A+ G Sbjct: 141 EAMTIIYTSGTTGKPKGVILTYGNHWASAVG 171
>MENE_BACAN (Q81K97) 2-succinylbenzoate--CoA ligase (EC 6.2.1.26) (OSB-CoA| synthetase) (o-succinylbenzoyl-CoA synthetase) Length = 481 Score = 38.1 bits (87), Expect = 0.022 Identities = 16/31 (51%), Positives = 21/31 (67%) Frame = +1 Query: 538 DVATICYTSGTTGTPKGAVLSHANFIANVAG 630 + TI YTSGTTG PKG +L++ N A+ G Sbjct: 140 EAMTIIYTSGTTGKPKGVILTYGNHWASAVG 170
>4CL2_ORYSA (Q42982) 4-coumarate--CoA ligase 2 (EC 6.2.1.12) (4CL 2)| (4-coumaroyl-CoA synthase 2) Length = 569 Score = 38.1 bits (87), Expect = 0.022 Identities = 15/32 (46%), Positives = 23/32 (71%) Frame = +1 Query: 532 PEDVATICYTSGTTGTPKGAVLSHANFIANVA 627 P+D + ++SGTTG PKG VL+H + ++ VA Sbjct: 210 PDDPVALPFSSGTTGLPKGVVLTHRSVVSGVA 241
>4CL1_PETCR (P14912) 4-coumarate--CoA ligase 1 (EC 6.2.1.12) (4CL 1)| (4-coumaroyl-CoA synthase 1) Length = 544 Score = 38.1 bits (87), Expect = 0.022 Identities = 15/31 (48%), Positives = 22/31 (70%) Frame = +1 Query: 535 EDVATICYTSGTTGTPKGAVLSHANFIANVA 627 +DV + Y+SGTTG PKG +L+H + +VA Sbjct: 182 DDVVALPYSSGTTGLPKGVMLTHKGLVTSVA 212
>AAS_YERPE (Q74RZ6) AAS bifunctional protein [Includes:| 2-acylglycerophosphoethanolamine acyltransferase (EC 2.3.1.40) (Acyl-[acyl-carrier-protein]--phospholipid O-acyltransferase) (2-acyl-GPE acyltransferase); Acyl-[acyl-carrier-protein] synthetase (EC 6 Length = 718 Score = 38.1 bits (87), Expect = 0.022 Identities = 17/34 (50%), Positives = 23/34 (67%) Frame = +1 Query: 523 PPKPEDVATICYTSGTTGTPKGAVLSHANFIANV 624 P + + A I +TSG+ G PKG V SHA+ +ANV Sbjct: 361 PQQADGSALILFTSGSEGNPKGVVHSHASLLANV 394
>LUCI_PHOPE (Q27757) Luciferin 4-monooxygenase (EC 1.13.12.7) (Luciferase)| Length = 545 Score = 37.7 bits (86), Expect = 0.028 Identities = 24/99 (24%), Positives = 51/99 (51%), Gaps = 4/99 (4%) Frame = +1 Query: 334 IFCVPQTLSTLLSFITQMPCVRLIVVVGGIDENMPSSPAAAGMEIITYSMLHRQG-HMSP 510 IFC T +L+ +++ V I+++ ++E++ G + + + ++ Sbjct: 125 IFCSKNTFQKVLNVKSKLKYVETIIILD-LNEDL------GGYQCLNNFISQNSDINLDV 177 Query: 511 QPFRPP---KPEDVATICYTSGTTGTPKGAVLSHANFIA 618 + F+P + + VA + ++SGTTG KG +L+H N +A Sbjct: 178 KKFKPNSFNRDDQVALVMFSSGTTGVSKGVMLTHKNIVA 216
>CAIC_ECOL6 (Q8FLA5) Probable crotonobetaine/carnitine-CoA ligase (EC 6.2.1.-)| Length = 522 Score = 37.7 bits (86), Expect = 0.028 Identities = 37/151 (24%), Positives = 62/151 (41%), Gaps = 4/151 (2%) Frame = +1 Query: 169 GIPKGARVGLYFINRPEWTIVDNACSAYSYVSVPLYDTLGPDAVQFIVNHAS----VEAI 336 GI KG +V L+ N PE+ + + VP+ L + +I+ ++ V + Sbjct: 63 GIRKGDKVALHLDNCPEFIFCWFGLAKIGAIMVPINARLLREESTWILQNSQACLLVTSA 122 Query: 337 FCVPQTLSTLLSFITQMPCVRLIVVVGGIDENMPSSPAAAGMEIITYSMLHRQGHMSPQP 516 P +Q+ + L +V D+ + S ++ L Q + Sbjct: 123 QFYPMYQQIQQEDASQLRHICLTDMVLPADDGVSS-----------FTQLKNQQPATLCY 171 Query: 517 FRPPKPEDVATICYTSGTTGTPKGAVLSHAN 609 P +D A I +TSGTT PKG V++H N Sbjct: 172 APPLSTDDTAEILFTSGTTSRPKGVVITHYN 202
>ACSA_AGRT5 (Q8UBV5) Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA| ligase) (Acyl-activating enzyme) Length = 651 Score = 37.7 bits (86), Expect = 0.028 Identities = 50/190 (26%), Positives = 74/190 (38%), Gaps = 19/190 (10%) Frame = +1 Query: 103 KWMTYGEAGTSRTAIGSGLICHGIPKGARVGLYFINRPEWTIVDNACSAYSYVSVPLYDT 282 K +TY + + + L HG+ KG RV +Y PE AC+ V ++ Sbjct: 104 KKITYNQLYDYVCRLANVLKKHGVKKGDRVTIYMPMIPEAAYAMLACARIGAVHSVVFGG 163 Query: 283 LGPDAVQF-IVNHASVEAIFC---------VPQTLSTLLSF---ITQMPCVRLIVVV--- 414 P+A+ IV+ S I C +P +T + Q V ++VV Sbjct: 164 FSPEALAGRIVDCESTFVITCDEGVRGGKPIPLKENTDKAIDIAAKQYVIVNKVLVVRRT 223 Query: 415 GGIDENMPSSPAAAGMEIITYSMLHRQGHMSPQPFRPP---KPEDVATICYTSGTTGTPK 585 GG P EI T +P PP + ED I YTSG+TG PK Sbjct: 224 GGKTGWAPGRDIWYHQEIATV-----------KPDCPPVKMRAEDPLFILYTSGSTGKPK 272 Query: 586 GAVLSHANFI 615 G + + ++ Sbjct: 273 GVLHTTGGYL 282
>Y1549_MYCTU (Q10777) Hypothetical protein Rv1549/MT1599.1| Length = 175 Score = 37.7 bits (86), Expect = 0.028 Identities = 21/88 (23%), Positives = 40/88 (45%) Frame = +1 Query: 88 TIGDYKWMTYGEAGTSRTAIGSGLICHGIPKGARVGLYFINRPEWTIVDNACSAYSYVSV 267 T G + MT+ + + +GL G+ +G V L NR E+ +D S Sbjct: 61 TPGGNQTMTWRDYAAQVRRVAAGLAGLGVRRGDTVSLMMANRIEFYPLDVGAQHVGATSF 120 Query: 268 PLYDTLGPDAVQFIVNHASVEAIFCVPQ 351 +Y+TL + + ++ ++A + + C Q Sbjct: 121 SVYNTLPAEQLTYVFDNAGTKVVICEQQ 148
>DLTA_STRMU (Q53526) D-alanine--poly(phosphoribitol) ligase subunit 1 (EC| 6.1.1.13) (D-alanine-activating enzyme) (DAE) (D-alanine-D-alanyl carrier protein ligase) (DCL) Length = 516 Score = 37.4 bits (85), Expect = 0.037 Identities = 21/53 (39%), Positives = 29/53 (54%), Gaps = 2/53 (3%) Frame = +1 Query: 466 IITYSMLHR--QGHMSPQPFRPPKPEDVATICYTSGTTGTPKGAVLSHANFIA 618 +I YS L + +S Q K +D I +TSGTTG PKG +SH N ++ Sbjct: 123 VIQYSQLEEIFKQKLSYQINHAVKGDDTYYIIFTSGTTGKPKGVQISHDNLLS 175
>ACSA_BRUSU (Q8FYQ3) Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA| ligase) (Acyl-activating enzyme) Length = 651 Score = 37.4 bits (85), Expect = 0.037 Identities = 42/184 (22%), Positives = 71/184 (38%), Gaps = 13/184 (7%) Frame = +1 Query: 103 KWMTYGEAGTSRTAIGSGLICHGIPKGARVGLYFINRPEWTIVDNACSAYSYVSVPLYDT 282 K +TY E + + + L HG+ KG RV +Y PE AC+ V ++ Sbjct: 104 KKITYRELYENVCRMANVLKKHGVKKGDRVTIYLPMIPEAAYAMLACARIGAVHSVVFAG 163 Query: 283 LGPDAVQFIVNHASVEAIFCV----------PQTLSTLLSFITQMPCVRLIVVVGGIDEN 432 P+A+ + E+ F + P L + + ++V + Sbjct: 164 FSPEALAGRI--VDCESTFVITADEGVRGGKPVALKENTDTAIDIAAKQYVMVNKVLVVR 221 Query: 433 MPSSPAAAGMEIITYSMLHRQGHMSPQPFRPPKP---EDVATICYTSGTTGTPKGAVLSH 603 + G + + Q S +P P+P ED I YTSG+TG PKG + + Sbjct: 222 RTGGKVSWGRG---RDLWYHQEVASVEPHCEPEPMNAEDPLFILYTSGSTGKPKGVLHTT 278 Query: 604 ANFI 615 ++ Sbjct: 279 GGYL 282
>ACSA_BRUME (Q8YJ48) Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA| ligase) (Acyl-activating enzyme) Length = 651 Score = 37.4 bits (85), Expect = 0.037 Identities = 42/184 (22%), Positives = 71/184 (38%), Gaps = 13/184 (7%) Frame = +1 Query: 103 KWMTYGEAGTSRTAIGSGLICHGIPKGARVGLYFINRPEWTIVDNACSAYSYVSVPLYDT 282 K +TY E + + + L HG+ KG RV +Y PE AC+ V ++ Sbjct: 104 KKITYRELYENVCRMANVLKKHGVKKGDRVTIYLPMIPEAAYAMLACARIGAVHSVVFAG 163 Query: 283 LGPDAVQFIVNHASVEAIFCV----------PQTLSTLLSFITQMPCVRLIVVVGGIDEN 432 P+A+ + E+ F + P L + + ++V + Sbjct: 164 FSPEALAGRI--VDCESTFVITADEGVRGGKPVALKENTDTAIDIAAKQYVMVNKVLVVR 221 Query: 433 MPSSPAAAGMEIITYSMLHRQGHMSPQPFRPPKP---EDVATICYTSGTTGTPKGAVLSH 603 + G + + Q S +P P+P ED I YTSG+TG PKG + + Sbjct: 222 RTGGKVSWGRG---RDLWYHQEVASVEPHCEPEPMNAEDPLFILYTSGSTGKPKGVLHTT 278 Query: 604 ANFI 615 ++ Sbjct: 279 GGYL 282
>ACS2_DEBHA (Q6BS00) Acetyl-coenzyme A synthetase 2 (EC 6.2.1.1) (Acetate--CoA| ligase 2) (Acyl-activating enzyme 2) Length = 679 Score = 37.4 bits (85), Expect = 0.037 Identities = 19/40 (47%), Positives = 24/40 (60%), Gaps = 3/40 (7%) Frame = +1 Query: 517 FRPPKP---EDVATICYTSGTTGTPKGAVLSHANFIANVA 627 + PP P ED + YTSG+TGTPKG V S A ++ A Sbjct: 262 YLPPVPVNSEDPLFLLYTSGSTGTPKGVVHSTAGYLLGAA 301
>ACSA_YERPE (Q8D1G8) Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA| ligase) (Acyl-activating enzyme) Length = 652 Score = 37.0 bits (84), Expect = 0.048 Identities = 43/185 (23%), Positives = 70/185 (37%), Gaps = 10/185 (5%) Frame = +1 Query: 103 KWMTYGEAGTSRTAIGSGLICHGIPKGARVGLYFINRPEWTIVDNACSAYSYVSVPLYDT 282 K +TY + + L G+ KG V +Y PE + AC+ V ++ Sbjct: 106 KTVTYKQLHHDVCQFANVLKSLGVKKGDVVAIYMPMVPEAAVAMLACARIGAVHSVIFGG 165 Query: 283 LGPDAV--QFIVNHAS--------VEAIFCVPQTLSTLLSFITQMPCVRLIVVVGGIDEN 432 PDAV + I +H+ + A +P L + + P + I V Sbjct: 166 FSPDAVAGRIIDSHSKLVITADEGIRAGRAIP--LKKNVDEALKNPAITSIKNVVVFQRT 223 Query: 433 MPSSPAAAGMEIITYSMLHRQGHMSPQPFRPPKPEDVATICYTSGTTGTPKGAVLSHANF 612 +S G ++ + ++ P ED I YTSG+TG PKG V + + Sbjct: 224 GNASYWEDGRDVWWHDLIKEASADCPP--EEMNAEDPLFILYTSGSTGKPKGVVHTTGGY 281 Query: 613 IANVA 627 + A Sbjct: 282 LVYAA 286
>4CL2_SOYBN (P31687) 4-coumarate--CoA ligase 2 (EC 6.2.1.12) (4CL 2)| (4-coumaroyl-CoA synthase 2) (Clone 4CL16) Length = 562 Score = 37.0 bits (84), Expect = 0.048 Identities = 14/32 (43%), Positives = 22/32 (68%) Frame = +1 Query: 532 PEDVATICYTSGTTGTPKGAVLSHANFIANVA 627 P+D + ++SGTTG PKG +L+H + +VA Sbjct: 198 PDDAVAMPFSSGTTGLPKGVILTHKSLTTSVA 229
>ACS1_CANAL (O94049) Acetyl-coenzyme A synthetase 1 (EC 6.2.1.1) (Acetate--CoA| ligase 1) (Acyl-activating enzyme 1) Length = 675 Score = 37.0 bits (84), Expect = 0.048 Identities = 44/182 (24%), Positives = 77/182 (42%), Gaps = 13/182 (7%) Frame = +1 Query: 109 MTYGEAGTSRTAIGSGLICHGIPKGARVGLYFINRPEWTIVDNAC----SAYSYV----- 261 +TYGE + + L G+ KG V +Y PE + A + +S V Sbjct: 129 ITYGELLKQVSKLAQALTKLGVKKGDSVAVYLPMIPEAIVTLLAIVRIGAMHSVVFAGFS 188 Query: 262 SVPLYDTLGPDAVQFIVNHASVEAIFCVPQTLSTLLSFITQMPCVRLIVVVGGI-DENMP 438 S L D + + ++ + +T + + + P VR ++V + ++P Sbjct: 189 SASLRDRILDADSRIVITADESKRGGKTIETKKIVDDALKECPKVRNVIVFKRTGNSHVP 248 Query: 439 SSPAAAGMEIITYSMLHRQGHMSPQPFRPPKP---EDVATICYTSGTTGTPKGAVLSHAN 609 SP G ++ + + + G P+ PP P ED + YTSG+TG PKG + A Sbjct: 249 FSP---GRDLWWHDEMAKYG-----PYFPPVPVNSEDPLFLLYTSGSTGKPKGVQHNTAG 300 Query: 610 FI 615 ++ Sbjct: 301 YL 302
>HMWP2_YEREN (P48633) High-molecular-weight protein 2 (HMWP2)| Length = 2035 Score = 37.0 bits (84), Expect = 0.048 Identities = 16/24 (66%), Positives = 18/24 (75%) Frame = +1 Query: 532 PEDVATICYTSGTTGTPKGAVLSH 603 P A I YTSG+TGTPKG V+SH Sbjct: 703 PTQPAYIIYTSGSTGTPKGVVISH 726
>AAS_PHOLL (Q7N7A9) AAS bifunctional protein [Includes:| 2-acylglycerophosphoethanolamine acyltransferase (EC 2.3.1.40) (Acyl-[acyl-carrier-protein]--phospholipid O-acyltransferase) (2-acyl-GPE acyltransferase); Acyl-[acyl-carrier-protein] synthetase (EC 6 Length = 639 Score = 37.0 bits (84), Expect = 0.048 Identities = 16/32 (50%), Positives = 22/32 (68%) Frame = +1 Query: 529 KPEDVATICYTSGTTGTPKGAVLSHANFIANV 624 KP+D A + +TSG+ KG V SHA+ +ANV Sbjct: 363 KPDDDALVLFTSGSDAVSKGVVHSHASLLANV 394
>ACSA_DEIRA (Q9RRL7) Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA| ligase) (Acyl-activating enzyme) Length = 649 Score = 37.0 bits (84), Expect = 0.048 Identities = 43/178 (24%), Positives = 68/178 (38%), Gaps = 9/178 (5%) Frame = +1 Query: 82 DGTIGDYKWMTYGEAGTSRTAIGSGLICHGIPKGARVGLYFINRPEWTIVDNACSAYSYV 261 +G G+ + TY E + L G+ G RV LY PE I AC+ V Sbjct: 106 EGEDGEVRTYTYAELLREVCKAANALEELGVVAGDRVTLYMPLIPEAAIAMLACARIGAV 165 Query: 262 SVPLYDTLGPDAVQFIVNHASVEAIFCV--------PQTLSTLLSFITQM-PCVRLIVVV 414 ++ A+ +N+A + + P TL ++ PC+ ++VV Sbjct: 166 HSIVFGGFSVSALADRINNAQSKLLITADAGYRRGKPVTLKINADEAAKLAPCLEHVLVV 225 Query: 415 GGIDENMPSSPAAAGMEIITYSMLHRQGHMSPQPFRPPKPEDVATICYTSGTTGTPKG 588 +P G ++ + ++ RQ E I YTSG+TG PKG Sbjct: 226 KRA--GIPLEWWTEGRDLWWHDVVDRQSDQHEATALDS--EHPLFILYTSGSTGAPKG 279
>ACSA_BRAJA (Q89WV5) Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA| ligase) (Acyl-activating enzyme) Length = 648 Score = 36.6 bits (83), Expect = 0.063 Identities = 44/189 (23%), Positives = 70/189 (37%), Gaps = 16/189 (8%) Frame = +1 Query: 109 MTYGEAGTSRTAIGSGLICHGIPKGARVGLYFINRPEWTIVDNACSAYSYVSVPLYDTLG 288 +TY E + + L + KG RV +Y PE AC+ + ++ Sbjct: 107 ITYKELHDEVCRMANILRTRNVKKGDRVTIYLPMIPEAAYAMLACARIGAIHSVVFAGFS 166 Query: 289 PDAVQFIVNHASVEAIFCVPQTL---------STLLSFITQMPCVRLIVVV----GGIDE 429 PD++ +N + I + L + + + + + V +VVV G ID Sbjct: 167 PDSLAQRINDCQSKVIITADEGLRGGKKVPLKANVDAALAKADGVDWVVVVKRTGGKIDM 226 Query: 430 NMPSS---PAAAGMEIITYSMLHRQGHMSPQPFRPPKPEDVATICYTSGTTGTPKGAVLS 600 N AA M + H ED I YTSG+TG PKG + + Sbjct: 227 NPTRDLWYHEAAAMVTTECPVEHMHA------------EDPLFILYTSGSTGQPKGVLHT 274 Query: 601 HANFIANVA 627 A ++ A Sbjct: 275 SAGYLVYAA 283
>FAD26_MYCTU (Q10976) Putative fatty-acid--CoA ligase fadD26 (EC 6.2.1.-)| (Acyl-CoA synthetase) Length = 583 Score = 36.6 bits (83), Expect = 0.063 Identities = 16/27 (59%), Positives = 20/27 (74%) Frame = +1 Query: 544 ATICYTSGTTGTPKGAVLSHANFIANV 624 A + YTSG+T TP G ++SH N IANV Sbjct: 168 AYLQYTSGSTRTPAGVIVSHTNVIANV 194
>DLTA_LISMF (Q721J2) D-alanine--poly(phosphoribitol) ligase subunit 1 (EC| 6.1.1.13) (D-alanine-activating enzyme) (DAE) (D-alanine-D-alanyl carrier protein ligase) (DCL) Length = 510 Score = 36.2 bits (82), Expect = 0.082 Identities = 22/68 (32%), Positives = 33/68 (48%), Gaps = 4/68 (5%) Frame = +1 Query: 427 ENMPSSPAAAGMEIITYSMLHR--QGHMSPQPFRPP--KPEDVATICYTSGTTGTPKGAV 594 E +PS+ G ++T L + H P + K +D I YTSG+TG PKG Sbjct: 109 EELPSNLTITGCPVLTQDQLMDALEKHFGEVPDKEACVKNDDNYYIIYTSGSTGNPKGVQ 168 Query: 595 LSHANFIA 618 +S N ++ Sbjct: 169 ISQNNLVS 176
>ACSA_VIBPA (Q87KU7) Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA| ligase) (Acyl-activating enzyme) Length = 650 Score = 36.2 bits (82), Expect = 0.082 Identities = 40/193 (20%), Positives = 69/193 (35%), Gaps = 16/193 (8%) Frame = +1 Query: 97 DYKWMTYGEAGTSRTAIGSGLICHGIPKGARVGLYFINRPEWTIVDNACSAYSYVSVPLY 276 D K +T+ E + L G+ KG V LY PE I AC+ V ++ Sbjct: 104 DDKTLTFNELHKEVCKFSNALKDQGVRKGDVVCLYMPMVPEAAIAMLACTRIGAVHTVVF 163 Query: 277 DTLGPDAVQFIVNHASVEAIFCVPQTLSTLLSFITQMPCVRLIVVVGGIDENMPSSPAAA 456 P+A+ + + + + + + R + + +DE + + Sbjct: 164 GGFSPEALSGRIIDSDAKVVITADEGVRG----------GRAVPLKKNVDEALTNPEVKT 213 Query: 457 GMEII----TYSMLHRQGHMSPQ------------PFRPPKPEDVATICYTSGTTGTPKG 588 +++ T + GH P K ED I YTSG+TG PKG Sbjct: 214 ISKVVVLKRTGGNVDWHGHRDVWWHEATAKVSDVCPPEEMKAEDPLFILYTSGSTGKPKG 273 Query: 589 AVLSHANFIANVA 627 + + ++ A Sbjct: 274 VLHTTGGYLVYAA 286
>DLTA_STRR6 (P0A399) D-alanine--poly(phosphoribitol) ligase subunit 1 (EC| 6.1.1.13) (D-alanine-activating enzyme) (DAE) (D-alanine-D-alanyl carrier protein ligase) (DCL) Length = 516 Score = 36.2 bits (82), Expect = 0.082 Identities = 16/32 (50%), Positives = 21/32 (65%) Frame = +1 Query: 523 PPKPEDVATICYTSGTTGTPKGAVLSHANFIA 618 P K +D I +TSGTTG PKG +SH N ++ Sbjct: 144 PVKGDDNYYIIFTSGTTGKPKGVQISHDNLLS 175
>DLTA_STRPN (P0A398) D-alanine--poly(phosphoribitol) ligase subunit 1 (EC| 6.1.1.13) (D-alanine-activating enzyme) (DAE) (D-alanine-D-alanyl carrier protein ligase) (DCL) Length = 516 Score = 36.2 bits (82), Expect = 0.082 Identities = 16/32 (50%), Positives = 21/32 (65%) Frame = +1 Query: 523 PPKPEDVATICYTSGTTGTPKGAVLSHANFIA 618 P K +D I +TSGTTG PKG +SH N ++ Sbjct: 144 PVKGDDNYYIIFTSGTTGKPKGVQISHDNLLS 175
>ACSA_HELPY (O25686) Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA| ligase) (Acyl-activating enzyme) Length = 662 Score = 36.2 bits (82), Expect = 0.082 Identities = 40/190 (21%), Positives = 72/190 (37%), Gaps = 12/190 (6%) Frame = +1 Query: 82 DGTIGDYKWMTYGEAGTSRTAIGSGLICH-GIPKGARVGLYFINRPEWTIVDNACSAYSY 258 +G +GDY +TY + + + L + KG RV +Y E + AC+ Sbjct: 104 EGEMGDYNVITYRKLHSEVNKTANLLKNEFNVKKGDRVIIYMPMIVESVYMMLACTRIGA 163 Query: 259 VSVPLYDTLGPDAVQFIVNHASVEAIFCVPQTLSTLLSFITQ-----------MPCVRLI 405 + ++ P+A++ +N A + + T ++ + P V Sbjct: 164 IHSIVFAGFSPEALRDRINDAQAKLVITADGTFRKGKPYMLKPALDKALENNACPSVEKA 223 Query: 406 VVVGGIDENMPSSPAAAGMEIITYSMLHRQGHMSPQPFRPPKPEDVATICYTSGTTGTPK 585 ++V N G + + M++ Q ED + YTSG+TG PK Sbjct: 224 LIV---IRNAKEIDYVRGRDFVYNEMVNYQSDKCEPEMMDS--EDPLFLLYTSGSTGKPK 278 Query: 586 GAVLSHANFI 615 G S A ++ Sbjct: 279 GVQHSSAGYL 288
>MENE_LISMO (P58730) 2-succinylbenzoate--CoA ligase (EC 6.2.1.26) (OSB-CoA| synthetase) (o-succinylbenzoyl-CoA synthetase) Length = 467 Score = 36.2 bits (82), Expect = 0.082 Identities = 18/47 (38%), Positives = 25/47 (53%) Frame = +1 Query: 469 ITYSMLHRQGHMSPQPFRPPKPEDVATICYTSGTTGTPKGAVLSHAN 609 I+YS L + P+ A+I YTSGTTG PKG + ++ N Sbjct: 114 ISYSELAETDYKEPELLETWDLSRTASIMYTSGTTGKPKGVIQTYEN 160
>LGRB_BREPA (Q70LM6) Linear gramicidin synthetase subunit B [Includes:| ATP-dependent alanine adenylase (AlaA) (Alanine activase); ATP-dependent D-leucine adenylase (D-LeuA) (D-leucine activase); Leucine racemase [ATP-hydrolyzing] (EC 5.1.1.-); ATP-depende Length = 5162 Score = 36.2 bits (82), Expect = 0.082 Identities = 34/175 (19%), Positives = 60/175 (34%) Frame = +1 Query: 91 IGDYKWMTYGEAGTSRTAIGSGLICHGIPKGARVGLYFINRPEWTIVDNACSAYSYVSVP 270 IG+ +TY + + L+ GI VG+ E I A VP Sbjct: 1540 IGEQGALTYAQLDAKANQLAHALLKRGIGSEDLVGICVERSSEMQIGQLAILKAGAAYVP 1599 Query: 271 LYDTLGPDAVQFIVNHASVEAIFCVPQTLSTLLSFITQMPCVRLIVVVGGIDENMPSSPA 450 + + + F++ A + + + L L + C +D + A Sbjct: 1600 MDPAYPRERLAFMIKDAGMSLVLTQERLLDALPQEAAALLC---------LDRDWQEIAA 1650 Query: 451 AAGMEIITYSMLHRQGHMSPQPFRPPKPEDVATICYTSGTTGTPKGAVLSHANFI 615 + + P + +A + YTSG+TGTPKG + H + + Sbjct: 1651 ES----------------TAAPAIKTNADQLAYVIYTSGSTGTPKGVEIEHGSLL 1689 Score = 35.0 bits (79), Expect = 0.18 Identities = 13/29 (44%), Positives = 21/29 (72%) Frame = +1 Query: 532 PEDVATICYTSGTTGTPKGAVLSHANFIA 618 P +++ + YTSG+TG PKG + H++ IA Sbjct: 3180 PTNLSYVIYTSGSTGLPKGVAIQHSSVIA 3208 Score = 33.1 bits (74), Expect = 0.70 Identities = 12/25 (48%), Positives = 19/25 (76%) Frame = +1 Query: 541 VATICYTSGTTGTPKGAVLSHANFI 615 +A + YTSG+TG PKG ++ HA+ + Sbjct: 601 LAYVIYTSGSTGKPKGVMIEHASLL 625 Score = 32.0 bits (71), Expect = 1.6 Identities = 12/27 (44%), Positives = 18/27 (66%) Frame = +1 Query: 535 EDVATICYTSGTTGTPKGAVLSHANFI 615 E +A + YTSG+TG PKG ++ H + Sbjct: 4236 ESLAYVIYTSGSTGLPKGTLVVHRGIV 4262
>LCFA_YERPE (Q8ZES9) Long-chain-fatty-acid--CoA ligase (EC 6.2.1.3) (Long-chain| acyl-CoA synthetase) Length = 562 Score = 35.8 bits (81), Expect = 0.11 Identities = 15/29 (51%), Positives = 20/29 (68%) Frame = +1 Query: 538 DVATICYTSGTTGTPKGAVLSHANFIANV 624 D A + YT GTTG KGA+L+H N +N+ Sbjct: 207 DTAFLQYTGGTTGVAKGAILTHRNMQSNL 235
>DIP2A_MOUSE (Q8BWT5) Disco-interacting protein 2 homolog A| Length = 1523 Score = 35.8 bits (81), Expect = 0.11 Identities = 29/100 (29%), Positives = 45/100 (45%), Gaps = 13/100 (13%) Frame = +1 Query: 346 PQTLSTLLSFITQMPCVRLIVVVG---------GIDENMPSSPAAAGMEIITYSMLHRQG 498 PQ L T L P V++IV V I + S AAA +++ T+ + Sbjct: 1029 PQNLGTTL------PTVKMIVEVSKSACVLSTQAITRLLKSKEAAAAVDVRTWPTILDTD 1082 Query: 499 HMSPQP----FRPPKPEDVATICYTSGTTGTPKGAVLSHA 606 + + FRPP P+ +A + ++ TTG G +SHA Sbjct: 1083 DIPKKKVASIFRPPSPDVLAYLDFSVSTTGILAGVKMSHA 1122
>DHBF_BACSU (P45745) Dimodular nonribosomal peptide synthetase| Length = 2378 Score = 35.8 bits (81), Expect = 0.11 Identities = 14/30 (46%), Positives = 20/30 (66%) Frame = +1 Query: 520 RPPKPEDVATICYTSGTTGTPKGAVLSHAN 609 +P P + A + YTSG+TG PKG ++ H N Sbjct: 1660 QPLSPLNTAYVIYTSGSTGVPKGVMIPHQN 1689
>ACS2_ZYGBA (Q96VC7) Acetyl-coenzyme A synthetase 2 (EC 6.2.1.1) (Acetate--CoA| ligase 2) (Acyl-activating enzyme 2) Length = 675 Score = 35.8 bits (81), Expect = 0.11 Identities = 18/40 (45%), Positives = 24/40 (60%), Gaps = 3/40 (7%) Frame = +1 Query: 517 FRPPKP---EDVATICYTSGTTGTPKGAVLSHANFIANVA 627 + PP P ED + YTSG+TG+PKG V S A ++ A Sbjct: 261 YLPPVPCNSEDPLFLLYTSGSTGSPKGVVHSTAGYLLGAA 300
>FAT2_YEAST (P38137) Peroxisomal-coenzyme A synthetase (EC 6.-.-.-)| Length = 543 Score = 35.8 bits (81), Expect = 0.11 Identities = 19/52 (36%), Positives = 27/52 (51%), Gaps = 3/52 (5%) Frame = +1 Query: 469 ITYSMLHRQGHMSPQPFRPP---KPEDVATICYTSGTTGTPKGAVLSHANFI 615 + Y L+ ++ P + P + DVA I +TSGTT TPK L H N + Sbjct: 164 VIYRSLNNAKFVNTNPVKFPGFARSSDVALILHTSGTTSTPKTVPLLHLNIV 215
>ACS2_CANAL (Q8NJN3) Acetyl-coenzyme A synthetase 2 (EC 6.2.1.1) (Acetate--CoA| ligase 2) (Acyl-activating enzyme 2) (Fragment) Length = 581 Score = 35.4 bits (80), Expect = 0.14 Identities = 40/181 (22%), Positives = 68/181 (37%), Gaps = 8/181 (4%) Frame = +1 Query: 109 MTYGEAGTSRTAIGSGLICHGIPKGARVGLYFINRPEWTIVDNACSAYSYVSVPLYDTLG 288 +TYG+ + + L GI KG V +Y + I A + ++ Sbjct: 124 LTYGDLLREVSKVAGVLQSWGIKKGDTVAVYLPMNAQAIIAMLAIARLGAAHSVIFAGFS 183 Query: 289 PDAVQFIVNHASVEAIFCVPQTLSTLLSFITQMPCVRLIVVVGGIDE-------NMPSSP 447 +++ VN AS +A+ + + + C +V +++ N P Sbjct: 184 AGSIKDRVNDASCKALITCDEGKRGGRTTNIKKLCDEALVDCPTVEKVLVYKRTNNPEIH 243 Query: 448 AAAGMEII-TYSMLHRQGHMSPQPFRPPKPEDVATICYTSGTTGTPKGAVLSHANFIANV 624 G + G++ P ED + YTSG+TGTPKG V S A ++ Sbjct: 244 LTEGRDYYWDVETAKFPGYLPPVSVNS---EDPLFLLYTSGSTGTPKGVVHSTAGYLLGA 300 Query: 625 A 627 A Sbjct: 301 A 301
>LGRA_BREPA (Q70LM7) Linear gramicidin synthetase subunit A [Includes:| ATP-dependent valine/leucine adenylase (Val/LeuA) (Valine/leucine activase); ATP-dependent glycine adenylase (GlyA) (Glycine activase)] Length = 2273 Score = 35.4 bits (80), Expect = 0.14 Identities = 30/116 (25%), Positives = 48/116 (41%), Gaps = 11/116 (9%) Frame = +1 Query: 289 PDAVQFIVNHASVE---AIFCVPQTLSTLLSFITQMPCVRLIVVVGGIDENM-----PSS 444 PD + ++ SVE AIF V + L P R+ + + P Sbjct: 1269 PDDLVMLMAERSVEMMVAIFAVLKAGGAYLPIDPHSPAERIAYIFADSGAKLVLAQSPFV 1328 Query: 445 PAAAGMEIITYSMLHRQGHMSPQPFRPP---KPEDVATICYTSGTTGTPKGAVLSH 603 A+ E++ L+ + PP +P D+ + YTSG+TG PKG ++ H Sbjct: 1329 EKASMAEVVLD--LNSASSYAADTSNPPLVNQPGDLVYVMYTSGSTGKPKGVMIEH 1382 Score = 35.0 bits (79), Expect = 0.18 Identities = 12/29 (41%), Positives = 20/29 (68%) Frame = +1 Query: 529 KPEDVATICYTSGTTGTPKGAVLSHANFI 615 +P+D+ + YTSG+TG KG ++ H N + Sbjct: 340 RPDDLVYVMYTSGSTGLAKGVMIEHHNLV 368
>DIP2A_HUMAN (Q14689) Disco-interacting protein 2 homolog A| Length = 1571 Score = 35.4 bits (80), Expect = 0.14 Identities = 29/100 (29%), Positives = 45/100 (45%), Gaps = 13/100 (13%) Frame = +1 Query: 346 PQTLSTLLSFITQMPCVRLIVVVG---------GIDENMPSSPAAAGMEIITYSMLHRQG 498 PQ L T L P V++IV V + + S AAA ++I T+ + Sbjct: 1077 PQNLGTTL------PTVKMIVEVSKSACVLTTQAVTRLLRSKEAAAAVDIRTWPTILDTD 1130 Query: 499 HMSPQP----FRPPKPEDVATICYTSGTTGTPKGAVLSHA 606 + + FRPP P+ +A + ++ TTG G +SHA Sbjct: 1131 DIPKKKIASVFRPPSPDVLAYLDFSVSTTGILAGVKMSHA 1170
>ACS2_KLULA (Q9Y7B5) Acetyl-coenzyme A synthetase 2 (EC 6.2.1.1) (Acetate--CoA| ligase 2) (Acyl-activating enzyme 2) Length = 684 Score = 35.4 bits (80), Expect = 0.14 Identities = 18/46 (39%), Positives = 27/46 (58%) Frame = +1 Query: 490 RQGHMSPQPFRPPKPEDVATICYTSGTTGTPKGAVLSHANFIANVA 627 ++G++ P P ED + YTSG+TG+PKG V S A ++ A Sbjct: 259 QRGYLPPVPVNS---EDPLFLLYTSGSTGSPKGVVHSTAGYLLGSA 301
>ACSA_RHILO (Q98ET8) Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA| ligase) (Acyl-activating enzyme) Length = 651 Score = 35.4 bits (80), Expect = 0.14 Identities = 44/189 (23%), Positives = 69/189 (36%), Gaps = 16/189 (8%) Frame = +1 Query: 97 DYKWMTYGEAGTSRTAIGSGLICHGIPKGARVGLYFINRPEWTIVDNACSAYSYVSVPLY 276 D K +TY E + + + HG+ KG RV +Y PE AC+ + ++ Sbjct: 103 DDKKITYNELYERVCRLANVMKKHGVKKGDRVTIYMPMIPEAAYAMLACTRIGAIHSIVF 162 Query: 277 DTLGPDAVQFIVNHASVEAIFCVPQTLSTLLSF-------------ITQMPCVRLIVVV- 414 PDA+ + + + L S V+ ++VV Sbjct: 163 GGFSPDALAGRIVDCESTFVITADEGLRGGKSIPLKENTDKAIDIAAKNFVMVKNVLVVR 222 Query: 415 --GGIDENMPSSPAAAGMEIITYSMLHRQGHMSPQPFRPPKPEDVATICYTSGTTGTPKG 588 GG P E+ T + P+ K ED I YTSG+TG PKG Sbjct: 223 RTGGKVGWAPGRDLWYHDEVATV-----KAECKPEKM---KAEDPLFILYTSGSTGKPKG 274 Query: 589 AVLSHANFI 615 + + A ++ Sbjct: 275 VLHTTAGYL 283
>ACS1_YEAST (Q01574) Acetyl-coenzyme A synthetase 1 (EC 6.2.1.1) (Acetate--CoA| ligase 1) (Acyl-activating enzyme 1) Length = 713 Score = 35.0 bits (79), Expect = 0.18 Identities = 34/158 (21%), Positives = 64/158 (40%), Gaps = 9/158 (5%) Frame = +1 Query: 169 GIPKGARVGLYFINRPEWTIVDNACSAYSYVSVPLYDTLGPDAVQFIVNHASVEAIFC-- 342 G+ KG V +Y PE I A S + ++ ++++ +N + + Sbjct: 185 GVRKGDTVAVYMPMVPEAIITLLAISRIGAIHSVVFAGFSSNSLRDRINDGDSKVVITTD 244 Query: 343 -------VPQTLSTLLSFITQMPCVRLIVVVGGIDENMPSSPAAAGMEIITYSMLHRQGH 501 V +T + + + P VR ++V + + A ++ T ++ + Sbjct: 245 ESNRGGKVIETKRIVDDALRETPGVRHVLVYRKTNNPSVAFHAPRDLDWAT----EKKKY 300 Query: 502 MSPQPFRPPKPEDVATICYTSGTTGTPKGAVLSHANFI 615 + P P ED + YTSG+TG PKG S A ++ Sbjct: 301 KTYYPCTPVDSEDPLFLLYTSGSTGAPKGVQHSTAGYL 338
>LGRC_BREPA (Q70LM5) Linear gramicidin synthetase subunit C [Includes:| ATP-dependent valine adenylase (ValA) (Valine activase); ATP-dependent D-valine adenylase (D-ValA) (D-valine activase); Valine racemase [ATP-hydrolyzing] (EC 5.1.1.-); ATP-dependent tr Length = 7756 Score = 35.0 bits (79), Expect = 0.18 Identities = 42/174 (24%), Positives = 72/174 (41%), Gaps = 5/174 (2%) Frame = +1 Query: 109 MTYGEAGTSRTAIGSGLICHGIPKGARVGLYFINRPEWTI----VDNACSAYSYVSVPLY 276 +TY + + L+ + VG+ PE I V A +AY VP+ Sbjct: 3089 LTYADLNQRANQLAHRLLAQEVKPDTLVGICVERSPEMIIGIFGVMKAGAAY----VPID 3144 Query: 277 DTLGPDAVQFIVNHASVEAIFCVPQTLSTLLSFITQMPCVRLIVVVGGIDENMP-SSPAA 453 L + + ++V + +I Q+L+ LL TQ R+I + G N P ++PA+ Sbjct: 3145 PALPQERIAYMVEDSQA-SILLTQQSLAELLPK-TQ---ARVICLDGDSLANEPVANPAS 3199 Query: 454 AGMEIITYSMLHRQGHMSPQPFRPPKPEDVATICYTSGTTGTPKGAVLSHANFI 615 E +++A + YTSG+TG PKG ++ H + + Sbjct: 3200 EVTE-----------------------QNLAYVMYTSGSTGLPKGVMVEHHSVV 3230 Score = 34.3 bits (77), Expect = 0.31 Identities = 13/24 (54%), Positives = 19/24 (79%) Frame = +1 Query: 535 EDVATICYTSGTTGTPKGAVLSHA 606 +++A + YTSG+TGTPKG + HA Sbjct: 4255 DNLAYVIYTSGSTGTPKGVEIEHA 4278 Score = 34.3 bits (77), Expect = 0.31 Identities = 12/27 (44%), Positives = 20/27 (74%) Frame = +1 Query: 535 EDVATICYTSGTTGTPKGAVLSHANFI 615 + +A + YTSG+TGTPKG +++H + Sbjct: 1677 DSLAYVIYTSGSTGTPKGVLVAHRGIV 1703 Score = 33.1 bits (74), Expect = 0.70 Identities = 33/171 (19%), Positives = 58/171 (33%), Gaps = 2/171 (1%) Frame = +1 Query: 109 MTYGEAGTSRTAIGSGLICHGIPKGARVGLYFINRPEWTIVDNACSAYSYVSVPLYDTLG 288 +TY E + L+ G+ VG+ PE + VPL Sbjct: 5668 LTYAELNERANQLAHRLLAEGVKPDELVGICVERSPEMIVAFLGVMKAGAAYVPLDPAHP 5727 Query: 289 PDAVQFIVNHASVEAIFCVPQTLSTLLSFITQMPCVRLIVVVGGIDE--NMPSSPAAAGM 462 + + +++ + + T S ++P V+ DE N P + A + Sbjct: 5728 QERIAYMIEDSQASVLL-------TQASLTDRLPASSRQVICLDSDELANEPVTNAETSV 5780 Query: 463 EIITYSMLHRQGHMSPQPFRPPKPEDVATICYTSGTTGTPKGAVLSHANFI 615 ++A + YTSG+TG PKG ++ H + I Sbjct: 5781 G----------------------EHNLAYVIYTSGSTGLPKGVMIEHRSVI 5809 Score = 32.3 bits (72), Expect = 1.2 Identities = 12/23 (52%), Positives = 17/23 (73%) Frame = +1 Query: 535 EDVATICYTSGTTGTPKGAVLSH 603 + +A + YTSG+TGTPKG + H Sbjct: 6839 DQLAYVIYTSGSTGTPKGVEIEH 6861 Score = 32.0 bits (71), Expect = 1.6 Identities = 12/27 (44%), Positives = 18/27 (66%) Frame = +1 Query: 535 EDVATICYTSGTTGTPKGAVLSHANFI 615 + +A + YTSG+TGTPKG + H + Sbjct: 611 DSLAYVIYTSGSTGTPKGVLAVHRGVV 637
>ESYN_FUSEQ (Q00869) Enniatin synthetase [Includes: N-methylcyclopeptide| synthetase (EC 6.3.2.-); S-adenosyl-L-methionine-dependent N-methyltransferase (EC 2.1.1.-)] Length = 3131 Score = 34.7 bits (78), Expect = 0.24 Identities = 13/28 (46%), Positives = 20/28 (71%) Frame = +1 Query: 529 KPEDVATICYTSGTTGTPKGAVLSHANF 612 K D+A + +TSG+TG PKG ++ H +F Sbjct: 625 KAHDLAYVIFTSGSTGIPKGIMIEHRSF 652 Score = 31.2 bits (69), Expect = 2.6 Identities = 14/33 (42%), Positives = 20/33 (60%) Frame = +1 Query: 505 SPQPFRPPKPEDVATICYTSGTTGTPKGAVLSH 603 SPQP +A + +TSG+TG PKG ++ H Sbjct: 1694 SPQP----SATSLAYVVFTSGSTGKPKGVMIEH 1722
>ACS1_DEBHA (Q6BQF2) Acetyl-coenzyme A synthetase 1 (EC 6.2.1.1) (Acetate--CoA| ligase 1) (Acyl-activating enzyme 1) Length = 671 Score = 34.7 bits (78), Expect = 0.24 Identities = 18/41 (43%), Positives = 23/41 (56%), Gaps = 3/41 (7%) Frame = +1 Query: 514 PFRPPKP---EDVATICYTSGTTGTPKGAVLSHANFIANVA 627 P+ PP P ED + YTSG+TG PKG S A ++ A Sbjct: 264 PYFPPVPVNSEDPLFLLYTSGSTGKPKGIQHSTAGYLLGAA 304
>DLTA_STRP8 (Q8P0J9) D-alanine--poly(phosphoribitol) ligase subunit 1 (EC| 6.1.1.13) (D-alanine-activating enzyme) (DAE) (D-alanine-D-alanyl carrier protein ligase) (DCL) Length = 512 Score = 34.3 bits (77), Expect = 0.31 Identities = 15/30 (50%), Positives = 20/30 (66%) Frame = +1 Query: 529 KPEDVATICYTSGTTGTPKGAVLSHANFIA 618 K +D I +TSGTTG PKG +SH N ++ Sbjct: 142 KGDDNYYIIFTSGTTGQPKGVQISHDNLLS 171
>DLTA_STRP6 (Q5XBN5) D-alanine--poly(phosphoribitol) ligase subunit 1 (EC| 6.1.1.13) (D-alanine-activating enzyme) (DAE) (D-alanine-D-alanyl carrier protein ligase) (DCL) Length = 512 Score = 34.3 bits (77), Expect = 0.31 Identities = 15/30 (50%), Positives = 20/30 (66%) Frame = +1 Query: 529 KPEDVATICYTSGTTGTPKGAVLSHANFIA 618 K +D I +TSGTTG PKG +SH N ++ Sbjct: 142 KGDDNYYIIFTSGTTGQPKGVQISHDNLLS 171
>DLTA_STRP3 (Q8K744) D-alanine--poly(phosphoribitol) ligase subunit 1 (EC| 6.1.1.13) (D-alanine-activating enzyme) (DAE) (D-alanine-D-alanyl carrier protein ligase) (DCL) Length = 512 Score = 34.3 bits (77), Expect = 0.31 Identities = 15/30 (50%), Positives = 20/30 (66%) Frame = +1 Query: 529 KPEDVATICYTSGTTGTPKGAVLSHANFIA 618 K +D I +TSGTTG PKG +SH N ++ Sbjct: 142 KGDDNYYIIFTSGTTGQPKGVQISHDNLLS 171
>DLTA_STRP1 (Q99ZA6) D-alanine--poly(phosphoribitol) ligase subunit 1 (EC| 6.1.1.13) (D-alanine-activating enzyme) (DAE) (D-alanine-D-alanyl carrier protein ligase) (DCL) Length = 512 Score = 34.3 bits (77), Expect = 0.31 Identities = 15/30 (50%), Positives = 20/30 (66%) Frame = +1 Query: 529 KPEDVATICYTSGTTGTPKGAVLSHANFIA 618 K +D I +TSGTTG PKG +SH N ++ Sbjct: 142 KGDDNYYIIFTSGTTGQPKGVQISHDNLLS 171
>DLTA_LACLA (Q9CG49) D-alanine--poly(phosphoribitol) ligase subunit 1 (EC| 6.1.1.13) (D-alanine-activating enzyme) (DAE) (D-alanine-D-alanyl carrier protein ligase) (DCL) Length = 499 Score = 34.3 bits (77), Expect = 0.31 Identities = 14/22 (63%), Positives = 16/22 (72%) Frame = +1 Query: 550 ICYTSGTTGTPKGAVLSHANFI 615 I YTSGTTG PKG +SH N + Sbjct: 149 IIYTSGTTGVPKGVEVSHDNLV 170
>ACSA_SHEON (Q8EDK3) Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA| ligase) (Acyl-activating enzyme) Length = 650 Score = 34.3 bits (77), Expect = 0.31 Identities = 36/171 (21%), Positives = 64/171 (37%), Gaps = 9/171 (5%) Frame = +1 Query: 109 MTYGEAGTSRTAIGSGLICHGIPKGARVGLYFINRPEWTIVDNACSAYSYVSVPLYDTLG 288 +TYGE T + L G+ +G V +Y PE + AC+ V ++ Sbjct: 108 ITYGELHTQVCKFANALRSQGVRRGDIVTIYMPMVPEAAVAMLACARIGAVHSVVFGGFS 167 Query: 289 PDAVQFIVNHASVEAIFCVPQ--------TLSTLLSFITQMPCVRLIVVVGGIDENMPSS 444 PD++ V + + + L + + P V + V + Sbjct: 168 PDSIASRVIDGKSKIVITSDEGMRGGRAIPLKRNIDDALKHPDVTSVEKVIVLKRTGGKI 227 Query: 445 PAAAGMEIITYSMLHRQG-HMSPQPFRPPKPEDVATICYTSGTTGTPKGAV 594 G ++ +S++ H + + ED + YTSG+TG PKG + Sbjct: 228 DWVEGRDVWWHSLVETASEHCAVEEM---GAEDPLFLLYTSGSTGNPKGVL 275
>ACSA_PHYBL (Q01576) Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA| ligase) (Acyl-activating enzyme) Length = 672 Score = 34.3 bits (77), Expect = 0.31 Identities = 17/41 (41%), Positives = 24/41 (58%) Frame = +1 Query: 505 SPQPFRPPKPEDVATICYTSGTTGTPKGAVLSHANFIANVA 627 SP+P ED + YTSG+TGTPKG + + ++ VA Sbjct: 263 SPEPM---SAEDPLFLLYTSGSTGTPKGILHTTGGYLLGVA 300
>DLTA_STRA5 (P59591) D-alanine--poly(phosphoribitol) ligase subunit 1 (EC| 6.1.1.13) (D-alanine-activating enzyme) (DAE) (D-alanine-D-alanyl carrier protein ligase) (DCL) Length = 511 Score = 34.3 bits (77), Expect = 0.31 Identities = 15/30 (50%), Positives = 20/30 (66%) Frame = +1 Query: 529 KPEDVATICYTSGTTGTPKGAVLSHANFIA 618 K +D I +TSGTTG PKG +SH N ++ Sbjct: 142 KGDDNYYIIFTSGTTGLPKGVQISHDNLLS 171
>DLTA_STRA3 (Q8VM67) D-alanine--poly(phosphoribitol) ligase subunit 1 (EC| 6.1.1.13) (D-alanine-activating enzyme) (DAE) (D-alanine-D-alanyl carrier protein ligase) (DCL) Length = 511 Score = 34.3 bits (77), Expect = 0.31 Identities = 15/30 (50%), Positives = 20/30 (66%) Frame = +1 Query: 529 KPEDVATICYTSGTTGTPKGAVLSHANFIA 618 K +D I +TSGTTG PKG +SH N ++ Sbjct: 142 KGDDNYYIIFTSGTTGLPKGVQISHDNLLS 171
>ACSA_MYCTU (O69635) Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA| ligase) (Acyl-activating enzyme) Length = 651 Score = 34.3 bits (77), Expect = 0.31 Identities = 43/198 (21%), Positives = 77/198 (38%), Gaps = 17/198 (8%) Frame = +1 Query: 73 VHADGT-IGDYKWMTYGEAGTSRTAIGSGLICHGIPKGARVGLYFINRPEWTIVDNACSA 249 +H +G +GD + +TY + + + L G+ G RV +Y PE I AC+ Sbjct: 94 IHWEGEPVGDRRTLTYSDLLAEVSKAANALTDLGLVAGDRVAIYLPLIPEAVIAMLACAR 153 Query: 250 YSYVSVPLYDTLGPDAVQFIVNHASVEAIFCVPQTLSTLLSFITQMPCVRLIVVVGGIDE 429 + ++ A+Q + A + L++ Q + + DE Sbjct: 154 LGIMHSVVFGGFTAAALQARIVDAQAKL----------LITADGQFRRGKPSPLKAAADE 203 Query: 430 NMPSSPAAAGMEIITY-----SMLHRQG------HM--SPQPFRPPKP---EDVATICYT 561 + + P + ++ M +G H+ S P P+P E + YT Sbjct: 204 ALAAIPDCSVEHVLVVRRTGIEMAWSEGRDLWWHHVVGSASPAHTPEPFDSEHPLFLLYT 263 Query: 562 SGTTGTPKGAVLSHANFI 615 SGTTG PKG + + ++ Sbjct: 264 SGTTGKPKGIMHTSGGYL 281
>ACSA_MYCBO (P59871) Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA| ligase) (Acyl-activating enzyme) Length = 651 Score = 34.3 bits (77), Expect = 0.31 Identities = 43/198 (21%), Positives = 77/198 (38%), Gaps = 17/198 (8%) Frame = +1 Query: 73 VHADGT-IGDYKWMTYGEAGTSRTAIGSGLICHGIPKGARVGLYFINRPEWTIVDNACSA 249 +H +G +GD + +TY + + + L G+ G RV +Y PE I AC+ Sbjct: 94 IHWEGEPVGDRRTLTYSDLLAEVSKAANALTDLGLVAGDRVAIYLPLIPEAVIAMLACAR 153 Query: 250 YSYVSVPLYDTLGPDAVQFIVNHASVEAIFCVPQTLSTLLSFITQMPCVRLIVVVGGIDE 429 + ++ A+Q + A + L++ Q + + DE Sbjct: 154 LGIMHSVVFGGFTAAALQARIVDAQAKL----------LITADGQFRRGKPSPLKAAADE 203 Query: 430 NMPSSPAAAGMEIITY-----SMLHRQG------HM--SPQPFRPPKP---EDVATICYT 561 + + P + ++ M +G H+ S P P+P E + YT Sbjct: 204 ALAAIPDCSVEHVLVVRRTGIEMAWSEGRDLWWHHVVGSASPAHTPEPFDSEHPLFLLYT 263 Query: 562 SGTTGTPKGAVLSHANFI 615 SGTTG PKG + + ++ Sbjct: 264 SGTTGKPKGIMHTSGGYL 281
>DLTA_LACPL (Q88VM6) D-alanine--poly(phosphoribitol) ligase subunit 1 (EC| 6.1.1.13) (D-alanine-activating enzyme) (DAE) (D-alanine-D-alanyl carrier protein ligase) (DCL) Length = 508 Score = 34.3 bits (77), Expect = 0.31 Identities = 15/30 (50%), Positives = 20/30 (66%) Frame = +1 Query: 535 EDVATICYTSGTTGTPKGAVLSHANFIANV 624 +D I +TSGTTG PKG +SH N ++ V Sbjct: 144 DDNYYIIFTSGTTGMPKGVQISHDNLVSYV 173
>MENE_LISMF (Q71YZ5) 2-succinylbenzoate--CoA ligase (EC 6.2.1.26) (OSB-CoA| synthetase) (o-succinylbenzoyl-CoA synthetase) Length = 467 Score = 34.3 bits (77), Expect = 0.31 Identities = 17/47 (36%), Positives = 25/47 (53%) Frame = +1 Query: 469 ITYSMLHRQGHMSPQPFRPPKPEDVATICYTSGTTGTPKGAVLSHAN 609 I+Y+ L + +P A++ YTSGTTG PKG V ++ N Sbjct: 114 ISYATLAETDYEAPALLETWDLSRAASVMYTSGTTGKPKGVVQTYEN 160
>MENE_LISIN (Q92AY8) 2-succinylbenzoate--CoA ligase (EC 6.2.1.26) (OSB-CoA| synthetase) (o-succinylbenzoyl-CoA synthetase) Length = 467 Score = 34.3 bits (77), Expect = 0.31 Identities = 16/47 (34%), Positives = 26/47 (55%) Frame = +1 Query: 469 ITYSMLHRQGHMSPQPFRPPKPEDVATICYTSGTTGTPKGAVLSHAN 609 I+Y L + ++ P + A++ YTSGTTG PKG + ++ N Sbjct: 114 ISYEELQQTTYVEPDLCKTWDLSRTASVMYTSGTTGKPKGVMQTYEN 160
>BACC_BACLI (O68008) Bacitracin synthetase 3 (BA3) [Includes: ATP-dependent| isoleucine adenylase (IleA) (Isoleucine activase); ATP-dependent D-phenylalanine adenylase (D-PheA) (D-phenylalanine activase); ATP-dependent histidine adenylase (HisA) (Histidine Length = 6359 Score = 33.9 bits (76), Expect = 0.41 Identities = 12/26 (46%), Positives = 20/26 (76%) Frame = +1 Query: 538 DVATICYTSGTTGTPKGAVLSHANFI 615 D+A + YTSG+TG PKG +++H + + Sbjct: 3140 DMAYVIYTSGSTGKPKGVMVNHQSIV 3165 Score = 32.7 bits (73), Expect = 0.91 Identities = 25/90 (27%), Positives = 41/90 (45%) Frame = +1 Query: 346 PQTLSTLLSFITQMPCVRLIVVVGGIDENMPSSPAAAGMEIITYSMLHRQGHMSPQPFRP 525 P+ L+ + I +++V G + EN+ A AG EI+ + ++ Sbjct: 4114 PEQLAKRTNEILSDSRAAILLVKGSVKENV----AFAG-EIVNVADGLIDAKVASNLSAS 4168 Query: 526 PKPEDVATICYTSGTTGTPKGAVLSHANFI 615 + A I YTSG+TG PKG + H N + Sbjct: 4169 GSADQNAYIIYTSGSTGKPKGVFVRHGNVV 4198 Score = 32.3 bits (72), Expect = 1.2 Identities = 14/22 (63%), Positives = 15/22 (68%) Frame = +1 Query: 538 DVATICYTSGTTGTPKGAVLSH 603 D A I YTSG+TG PKG V H Sbjct: 600 DTAYIIYTSGSTGMPKGVVTPH 621 Score = 30.0 bits (66), Expect = 5.9 Identities = 12/20 (60%), Positives = 16/20 (80%) Frame = +1 Query: 538 DVATICYTSGTTGTPKGAVL 597 D+A I YTSG+TG PKG ++ Sbjct: 1641 DLAYIIYTSGSTGKPKGVLI 1660
>DLTA_LACRH (P35854) D-alanine--poly(phosphoribitol) ligase subunit 1 (EC| 6.1.1.13) (D-alanine-activating enzyme) (DAE) (D-alanine-D-alanyl carrier protein ligase) (DCL) Length = 506 Score = 33.9 bits (76), Expect = 0.41 Identities = 15/30 (50%), Positives = 20/30 (66%) Frame = +1 Query: 535 EDVATICYTSGTTGTPKGAVLSHANFIANV 624 +D I +TSGTTG PKG +SH N ++ V Sbjct: 144 DDNYYIIFTSGTTGKPKGVQISHDNLLSYV 173
>ACSA_PRB01 (Q9F7R5) Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA| ligase) (Acyl-activating enzyme) Length = 641 Score = 33.9 bits (76), Expect = 0.41 Identities = 42/188 (22%), Positives = 70/188 (37%), Gaps = 15/188 (7%) Frame = +1 Query: 97 DYKWMTYGEAGTSRTAIGSGLICHGIPKGARVGLYFINRPEWTIVDNACSAYSYVSVPLY 276 D K +TY E + L G+ KG+RV +Y E AC+ V ++ Sbjct: 99 DSKELTYKELHDEVCKFANVLKDLGVQKGSRVCIYMPMIIETAFAMLACTRIGAVHSVVF 158 Query: 277 DTLGPDAVQFIVNHASVEAIFCVPQTLSTLLSFITQMPCVRLIVVVGGIDENMPSSPAA- 453 P++++ + A + + + L + + + +DE + P Sbjct: 159 GGFSPESLKDRILDADCKIVITADEGLRG----------GKKVPLKSNVDEALLGCPDVK 208 Query: 454 -------AGMEI-------ITYSMLHRQGHMSPQPFRPPKPEDVATICYTSGTTGTPKGA 591 G EI + Y L + P P ED I YTSG+TG PKG Sbjct: 209 NTLVIKRTGGEINWDDKKDVWYEDLVKDVSNKCAP-EPMDSEDPLFILYTSGSTGKPKGV 267 Query: 592 VLSHANFI 615 + + A ++ Sbjct: 268 LHTTAGYL 275
>FAD28_MYCBO (Q02278) Putative fatty-acid--CoA ligase fadD28 (EC 6.2.1.-)| (Acyl-CoA synthetase) Length = 580 Score = 33.9 bits (76), Expect = 0.41 Identities = 30/126 (23%), Positives = 50/126 (39%), Gaps = 30/126 (23%) Frame = +1 Query: 334 IFCVPQTLSTLLSFITQMPCVRLIVVV----GGIDENMP------SSPAA-----AGMEI 468 + PQ L +++F+ + R+ V + GG+ + SSP A + ++ Sbjct: 66 VISAPQGLEYVVAFLGALQAGRIAVPLSVPQGGVTDERSDSVLSDSSPVAILTTSSAVDD 125 Query: 469 ITYSMLHRQGHMSPQ---------------PFRPPKPEDVATICYTSGTTGTPKGAVLSH 603 + + R G P F+ + A + YTSG+T TP G V+SH Sbjct: 126 VVQHVARRPGESPPSIIEVDLLDLDAPNGYTFKEDEYPSTAYLQYTSGSTRTPAGVVMSH 185 Query: 604 ANFIAN 621 N N Sbjct: 186 QNVRVN 191
>DLTA_LISMO (Q8Y8D4) D-alanine--poly(phosphoribitol) ligase subunit 1 (EC| 6.1.1.13) (D-alanine-activating enzyme) (DAE) (D-alanine-D-alanyl carrier protein ligase) (DCL) Length = 510 Score = 33.1 bits (74), Expect = 0.70 Identities = 20/68 (29%), Positives = 32/68 (47%), Gaps = 4/68 (5%) Frame = +1 Query: 427 ENMPSSPAAAGMEIITYSMLHR--QGHMSPQPFRPP--KPEDVATICYTSGTTGTPKGAV 594 E +P++ G ++T L + H P + +D I YTSG+TG PKG Sbjct: 109 EELPNNLTITGCPVLTQDQLMDALEKHFGEVPDKEACVNNDDNYYIIYTSGSTGNPKGVQ 168 Query: 595 LSHANFIA 618 +S N ++ Sbjct: 169 ISQNNLVS 176
>S27A5_RAT (Q9ES38) Bile acyl-CoA synthetase (EC 6.2.1.7) (BACS) (Bile acid| CoA ligase) (BA-CoA ligase) (BAL) (Cholate--CoA ligase) (Very long chain acyl-CoA synthetase-related protein) (VLACS-related) (VLACSR) (Fatty acid transport protein 5) (FATP-5) (S Length = 690 Score = 33.1 bits (74), Expect = 0.70 Identities = 15/24 (62%), Positives = 16/24 (66%) Frame = +1 Query: 544 ATICYTSGTTGTPKGAVLSHANFI 615 A YTSGTTG PK A+LSH I Sbjct: 290 AIFIYTSGTTGLPKPAILSHERVI 313
>ACS2_ASHGO (Q750T7) Acetyl-coenzyme A synthetase 2 (EC 6.2.1.1) (Acetate--CoA| ligase 2) (Acyl-activating enzyme 2) Length = 687 Score = 33.1 bits (74), Expect = 0.70 Identities = 37/185 (20%), Positives = 72/185 (38%), Gaps = 8/185 (4%) Frame = +1 Query: 97 DYKWMTYGEAGTSRTAIGSGLICHGIPKGARVGLYFINRPEWTIVDNACSAYSYVSVPLY 276 D + +T+GE + + L G+ KG V +Y PE + A + V ++ Sbjct: 119 DNRVVTFGELLRQVSQVAGVLQSWGVKKGDTVAVYMPMIPEAVVAMLAVARLGAVHSVIF 178 Query: 277 DTLGPDAVQFIVNHASVEAIFCVPQTLSTLLSFITQMPCVRLIVVVGGIDENM------- 435 +++ + A + + + + T+ + VG + + Sbjct: 179 AGFSSGSLRDRIVDAESKVVITCDEGRRGGKTVHTKKIVDEGLAGVGVVSHILVFQRTGS 238 Query: 436 PSSPAAAGMEIITYSMLHRQ-GHMSPQPFRPPKPEDVATICYTSGTTGTPKGAVLSHANF 612 P AG + + + +Q G++ P ED + YTSG+TG+PKG V + + Sbjct: 239 EGIPMKAGRDFWWHEEVRKQRGYLPPVSVNA---EDPIFLLYTSGSTGSPKGVVHTTGGY 295 Query: 613 IANVA 627 + A Sbjct: 296 LLGAA 300
>MENE_STAAU (Q53634) 2-succinylbenzoate--CoA ligase (EC 6.2.1.26) (OSB-CoA| synthetase) (o-succinylbenzoyl-CoA synthetase) Length = 492 Score = 32.7 bits (73), Expect = 0.91 Identities = 43/164 (26%), Positives = 65/164 (39%), Gaps = 15/164 (9%) Frame = +1 Query: 184 ARVGLYFINRPEWTIVDNACSAYSYVSVPLYDTLGPDAVQFIVNHASVEAIFCVPQTLST 363 +RVGLY N + I+ +AC + + L P+ + + V+ IFC TL Sbjct: 47 SRVGLYIDNSIQSIILIHACWLANIEIAMINTRLTPNEMTNQMKSIDVQLIFC---TLPL 103 Query: 364 LLSFITQMPCVRLIVVVGGIDENMPSSPAAAGMEIITYSMLHR----QGHMSPQPFRPPK 531 L IV + I+ AG +I T S+L Q S + P + Sbjct: 104 ELRGFQ-------IVSLDDIE--------FAGRDITTNSLLDNTMGIQYETSNETVVPKE 148 Query: 532 P-----------EDVATICYTSGTTGTPKGAVLSHANFIANVAG 630 +D+A+I +TSGTTG K + N A+ G Sbjct: 149 SPSNILNTSFNLDDIASIMFTSGTTGPQKAVPQTFRNHYASAIG 192
>MENE_STAAC (Q5HEY2) 2-succinylbenzoate--CoA ligase (EC 6.2.1.26) (OSB-CoA| synthetase) (o-succinylbenzoyl-CoA synthetase) Length = 492 Score = 32.7 bits (73), Expect = 0.91 Identities = 43/164 (26%), Positives = 65/164 (39%), Gaps = 15/164 (9%) Frame = +1 Query: 184 ARVGLYFINRPEWTIVDNACSAYSYVSVPLYDTLGPDAVQFIVNHASVEAIFCVPQTLST 363 +RVGLY N + I+ +AC + + L P+ + + V+ IFC TL Sbjct: 47 SRVGLYIDNSIQSIILIHACWLANIEIAMINTRLTPNEMTNQMKSIDVQLIFC---TLPL 103 Query: 364 LLSFITQMPCVRLIVVVGGIDENMPSSPAAAGMEIITYSMLHR----QGHMSPQPFRPPK 531 L IV + I+ AG +I T S+L Q S + P + Sbjct: 104 ELRGFQ-------IVSLDDIE--------FAGRDITTNSLLDNTMGIQYETSNETVVPKE 148 Query: 532 P-----------EDVATICYTSGTTGTPKGAVLSHANFIANVAG 630 +D+A+I +TSGTTG K + N A+ G Sbjct: 149 SPSNILNTSFNLDDIASIMFTSGTTGPQKAVPQTFRNHYASAIG 192
>FAD25_MYCTU (Q50586) Putative fatty-acid--CoA ligase fadD25 (EC 6.2.1.-)| (Acyl-CoA synthetase) Length = 583 Score = 32.7 bits (73), Expect = 0.91 Identities = 35/130 (26%), Positives = 55/130 (42%), Gaps = 17/130 (13%) Frame = +1 Query: 283 LGPDAVQFIVNH-ASVEA-IFCVPQTLS--------TLLSFITQMPCVRLIV--VVGGID 426 L P ++ ++V+ AS++A I VP ++ T+ F P + L VV + Sbjct: 70 LAPQSLDYVVSFIASLQAGIVAVPLSIPQGGAHDERTVSVFADTAPAIVLTASSVVDNVV 129 Query: 427 ENMPSSPAAAGMEIITYSMLH-----RQGHMSPQPFRPPKPEDVATICYTSGTTGTPKGA 591 E + P +I L G S P D+ + YTSG+T TP G Sbjct: 130 EYVQPQPGQNAPAVIEVDRLDLDARPSSGSRSAAHGHP----DILYLQYTSGSTRTPAGV 185 Query: 592 VLSHANFIAN 621 ++S+ N AN Sbjct: 186 MVSNKNLFAN 195
>ACS2_CANGA (Q6FXI2) Acetyl-coenzyme A synthetase 2 (EC 6.2.1.1) (Acetate--CoA| ligase 2) (Acyl-activating enzyme 2) Length = 683 Score = 32.7 bits (73), Expect = 0.91 Identities = 16/40 (40%), Positives = 23/40 (57%), Gaps = 3/40 (7%) Frame = +1 Query: 517 FRPPKP---EDVATICYTSGTTGTPKGAVLSHANFIANVA 627 + PP P ED + YTSG+TG+PKG V + ++ A Sbjct: 262 YLPPVPCDAEDPLFLLYTSGSTGSPKGIVHTTGGYLLGAA 301
>ACVS_STRCL (Q01757) N-(5-amino-5-carboxypentanoyl)-L-cysteinyl-D-valine| synthase (EC 6.3.2.26) (Delta-(L-alpha-aminoadipyl)-L-cysteinyl-D-valine synthetase) (ACV synthetase) (ACVS) (Fragment) Length = 805 Score = 32.7 bits (73), Expect = 0.91 Identities = 16/43 (37%), Positives = 24/43 (55%) Frame = +1 Query: 496 GHMSPQPFRPPKPEDVATICYTSGTTGTPKGAVLSHANFIANV 624 G +S +P D+A + YTSGTTG PKG H + + ++ Sbjct: 404 GLLSVKPELALGVRDLAYLTYTSGTTGVPKGVPKYHDSVVNSI 446
>FAD21_MYCTU (P63523) Putative fatty-acid--CoA ligase fadD21 (EC 6.2.1.-)| (Acyl-CoA synthetase) Length = 578 Score = 32.3 bits (72), Expect = 1.2 Identities = 31/126 (24%), Positives = 48/126 (38%), Gaps = 29/126 (23%) Frame = +1 Query: 331 AIFCVPQTLSTLLSFITQMPCVRLIVV-----VGGIDENMPSSPAAAGMEIITYSM---- 483 A+ PQ L+ + +F+ M + V +G DE + + A A +I + Sbjct: 65 AVILAPQGLAYIAAFLGSMQAGAIAVPLSVPQIGSHDERVSAVLADASPSVILTTSAVAE 124 Query: 484 -----LHRQGHMSPQP---------------FRPPKPEDVATICYTSGTTGTPKGAVLSH 603 +HR + P FR A + YTSG+T P G ++SH Sbjct: 125 AVAEHIHRPNTNNVGPIIEIDSLDLTGNSPSFRVKDLPSAAYLQYTSGSTRAPAGVMISH 184 Query: 604 ANFIAN 621 N AN Sbjct: 185 RNLQAN 190
>FAD21_MYCBO (P63524) Putative fatty-acid--CoA ligase fadD21 (EC 6.2.1.-)| (Acyl-CoA synthetase) Length = 578 Score = 32.3 bits (72), Expect = 1.2 Identities = 31/126 (24%), Positives = 48/126 (38%), Gaps = 29/126 (23%) Frame = +1 Query: 331 AIFCVPQTLSTLLSFITQMPCVRLIVV-----VGGIDENMPSSPAAAGMEIITYSM---- 483 A+ PQ L+ + +F+ M + V +G DE + + A A +I + Sbjct: 65 AVILAPQGLAYIAAFLGSMQAGAIAVPLSVPQIGSHDERVSAVLADASPSVILTTSAVAE 124 Query: 484 -----LHRQGHMSPQP---------------FRPPKPEDVATICYTSGTTGTPKGAVLSH 603 +HR + P FR A + YTSG+T P G ++SH Sbjct: 125 AVAEHIHRPNTNNVGPIIEIDSLDLTGNSPSFRVKDLPSAAYLQYTSGSTRAPAGVMISH 184 Query: 604 ANFIAN 621 N AN Sbjct: 185 RNLQAN 190
>S27A6_HUMAN (Q9Y2P4) Long-chain fatty acid transport protein 6 (Fatty acid| transport protein 6) (FATP-6) (Very long-chain acyl-CoA synthetase homolog 1) (VLCSH1) (hVLCS-H1) (Fatty-acid-coenzyme A ligase, very long-chain 2) (Solute carrier family 27 membe Length = 619 Score = 32.3 bits (72), Expect = 1.2 Identities = 31/117 (26%), Positives = 56/117 (47%), Gaps = 21/117 (17%) Frame = +1 Query: 340 CVPQTLSTLLSFITQMPCVR------LIV---VVGGIDENMPS---SPAAAGM-EIITYS 480 CV L+T + + + C+R L+V ++G ++E +PS + + GM + + Sbjct: 130 CVVAFLNTNIRSNSLLNCIRACGPRALVVGADLLGTVEEILPSLSENISVWGMKDSVPQG 189 Query: 481 MLHRQGHMSPQPFRP-PKPEDVATIC-------YTSGTTGTPKGAVLSHANFIANVA 627 ++ + +S P P P+ V ++ +TSGTTG PK AV+S + A Sbjct: 190 VISLKEKLSTSPDEPVPRSHHVVSLLKSTCLYIFTSGTTGLPKAAVISQLQVLRGSA 246
>ACS2_YEAST (P52910) Acetyl-coenzyme A synthetase 2 (EC 6.2.1.1) (Acetate--CoA| ligase 2) (Acyl-activating enzyme 2) Length = 683 Score = 32.3 bits (72), Expect = 1.2 Identities = 41/187 (21%), Positives = 73/187 (39%), Gaps = 10/187 (5%) Frame = +1 Query: 97 DYKWMTYGEAGTSRTAIGSGLICHGIPKGARVGLYFINRPEWTIVDNACSAYSYVSVPLY 276 D K +T+GE + I L G+ KG V +Y PE I A + + ++ Sbjct: 119 DNKIITFGELLRKVSQIAGVLKSWGVKKGDTVAIYLPMIPEAVIAMLAVARIGAIHSVVF 178 Query: 277 DTLGPDAVQFIVNHASVEAIFCVPQ------TLSTLLSFITQMPCVRLIVVVGGIDENMP 438 +++ V A+ + + + T++T + V L+ + Sbjct: 179 AGFSAGSLKDRVVDANSKVVITCDEGKRGGKTINTKKIVDEGLNGVDLVSRILVFQRTGT 238 Query: 439 SS-PAAAGMEIITYSMLHRQGHMSPQPFRPP---KPEDVATICYTSGTTGTPKGAVLSHA 606 P AG + + +Q + + PP ED + YTSG+TG+PKG V + Sbjct: 239 EGIPMKAGRDYWWHEEAAKQ-----RTYLPPVSCDAEDPLFLLYTSGSTGSPKGVVHTTG 293 Query: 607 NFIANVA 627 ++ A Sbjct: 294 GYLLGAA 300
>MENE_STAAW (Q8NVZ4) 2-succinylbenzoate--CoA ligase (EC 6.2.1.26) (OSB-CoA| synthetase) (o-succinylbenzoyl-CoA synthetase) Length = 492 Score = 32.3 bits (72), Expect = 1.2 Identities = 39/158 (24%), Positives = 63/158 (39%), Gaps = 9/158 (5%) Frame = +1 Query: 184 ARVGLYFINRPEWTIVDNACSAYSYVSVPLYDTLGPDAVQFIVNHASVEAIFCVPQTLST 363 +RVGLY N + I+ +AC + + L P+ ++ + V+ IFC T Sbjct: 47 SRVGLYIDNSIQSIILIHACWLANIEIAMINTRLTPNEMKNQMRSIDVQLIFC------T 100 Query: 364 LLSFITQMPCVRLI-VVVGGIDENMPSSPAAAGMEIITYSMLHRQGHMSPQPFRPPKP-- 534 L + V L + G D M G+ T + + + + P P Sbjct: 101 LPLELRGFQIVSLDDIEFAGTDITMN------GLLDNTMDIQYDTSNETVVPKESPSNIL 154 Query: 535 ------EDVATICYTSGTTGTPKGAVLSHANFIANVAG 630 +D+A+I +TSGTTG K + N A+ G Sbjct: 155 NTSFNLDDIASIMFTSGTTGPQKAVPQTFRNHYASAIG 192
>MENE_STAAS (Q6G8D6) 2-succinylbenzoate--CoA ligase (EC 6.2.1.26) (OSB-CoA| synthetase) (o-succinylbenzoyl-CoA synthetase) Length = 492 Score = 32.3 bits (72), Expect = 1.2 Identities = 39/158 (24%), Positives = 63/158 (39%), Gaps = 9/158 (5%) Frame = +1 Query: 184 ARVGLYFINRPEWTIVDNACSAYSYVSVPLYDTLGPDAVQFIVNHASVEAIFCVPQTLST 363 +RVGLY N + I+ +AC + + L P+ ++ + V+ IFC T Sbjct: 47 SRVGLYIDNSIQSIILIHACWLANIEIAMINTRLTPNEMKNQMRSIDVQLIFC------T 100 Query: 364 LLSFITQMPCVRLI-VVVGGIDENMPSSPAAAGMEIITYSMLHRQGHMSPQPFRPPKP-- 534 L + V L + G D M G+ T + + + + P P Sbjct: 101 LPLELRGFQIVSLDDIEFAGTDITMN------GLLDNTMDIQYDTSNETVVPKESPSNIL 154 Query: 535 ------EDVATICYTSGTTGTPKGAVLSHANFIANVAG 630 +D+A+I +TSGTTG K + N A+ G Sbjct: 155 NTSFNLDDIASIMFTSGTTGPQKAVPQTFRNHYASAIG 192
>ACSA_PYRAE (O93730) Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA| ligase) (Acyl-activating enzyme) Length = 670 Score = 32.3 bits (72), Expect = 1.2 Identities = 36/157 (22%), Positives = 62/157 (39%), Gaps = 15/157 (9%) Frame = +1 Query: 169 GIPKGARVGLYFINRPEWTIVDNACSAYSYVSVPLYDTLGPDAVQFIVNHASVEAIFC-- 342 G+ KG ++ LY PE I A ++ ++ DA+ +N + + Sbjct: 142 GVKKGDKITLYLPMVPELPITMLAAWRIGAITSVVFSGFSADALAERINDSQSRIVITAD 201 Query: 343 ----------VPQTLSTLLSFITQMPCVRLIVVVGGIDENMPSSPAAAGMEIITYSMLHR 492 + + + L T + V ++ +G + P G + ++ Sbjct: 202 GFWRRGRVVRLKEVVDAALEKATGVESVIVLPRLG-----LKDVPMTEGRDYWWNKLM-- 254 Query: 493 QGHMSPQPFRPPKP---EDVATICYTSGTTGTPKGAV 594 QG + P + P+P E + I YTSGTTG PKG V Sbjct: 255 QG-IPPNAYIEPEPVESEHPSFILYTSGTTGKPKGIV 290
>S27A4_MOUSE (Q91VE0) Long-chain fatty acid transport protein 4 (EC 6.2.1.-)| (Fatty acid transport protein 4) (FATP-4) (Solute carrier family 27 member 4) Length = 643 Score = 32.0 bits (71), Expect = 1.6 Identities = 35/173 (20%), Positives = 66/173 (38%), Gaps = 1/173 (0%) Frame = +1 Query: 97 DYKWMTYGEAGTSRTAIGSGLICHGIPKGARVGLYFINRPEWTIVDNACSAYSYVSVPLY 276 D W T+ + +++ + L G+ G V L+ NR E+ + + + + Sbjct: 99 DTHW-TFRQLDEYSSSVANFLQARGLASGNVVALFMENRNEFVGLWLGMAKLGVEAALIN 157 Query: 277 DTLGPDAVQFIVNHASVEAIFCVPQTLSTLLSFITQMPCVRLIVVVGGIDENMPSSPAAA 456 L DA++ ++ + A+ + S + + + G + S Sbjct: 158 TNLRRDALRHCLDTSKARALIFGSEMASAICEIHASLEPTLSLFCSGSWEP----STVPV 213 Query: 457 GMEIITYSMLHRQGHMSPQPFRPPKP-EDVATICYTSGTTGTPKGAVLSHANF 612 E + + H+ P P K D YTSGTTG PK A++ H+ + Sbjct: 214 STEHLDPLLEDAPKHL---PSHPDKGFTDKLFYIYTSGTTGLPKAAIVVHSRY 263
>DLTA_BACSU (P39581) D-alanine--poly(phosphoribitol) ligase subunit 1 (EC| 6.1.1.13) (D-alanine-activating enzyme) (DAE) (D-alanine-D-alanyl carrier protein ligase) (DCL) Length = 503 Score = 32.0 bits (71), Expect = 1.6 Identities = 22/56 (39%), Positives = 29/56 (51%), Gaps = 3/56 (5%) Frame = +1 Query: 451 AAGMEIITYS---MLHRQGHMSPQPFRPPKPEDVATICYTSGTTGTPKGAVLSHAN 609 A G +I T S +L +G Q + K + I YTSG+TG PKG +S AN Sbjct: 113 AVGQQIQTVSAEELLENEGGSVSQD-QWVKEHETFYIIYTSGSTGNPKGVQISAAN 167
>LUCI_LUCLA (Q01158) Luciferin 4-monooxygenase (EC 1.13.12.7) (Luciferase)| Length = 548 Score = 32.0 bits (71), Expect = 1.6 Identities = 14/29 (48%), Positives = 19/29 (65%) Frame = +1 Query: 529 KPEDVATICYTSGTTGTPKGAVLSHANFI 615 + E VA I +SG+TG PKG L+H N + Sbjct: 190 RKEQVALIMNSSGSTGLPKGVQLTHENAV 218
>LUCI_LUCCR (P13129) Luciferin 4-monooxygenase (EC 1.13.12.7) (Luciferase)| Length = 548 Score = 32.0 bits (71), Expect = 1.6 Identities = 14/29 (48%), Positives = 19/29 (65%) Frame = +1 Query: 529 KPEDVATICYTSGTTGTPKGAVLSHANFI 615 + E VA I +SG+TG PKG L+H N + Sbjct: 190 RKEQVALIMNSSGSTGLPKGVQLTHENTV 218
>ACSA_PASMU (Q9CMW1) Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA| ligase) (Acyl-activating enzyme) Length = 653 Score = 32.0 bits (71), Expect = 1.6 Identities = 40/186 (21%), Positives = 66/186 (35%), Gaps = 8/186 (4%) Frame = +1 Query: 82 DGTIGDYKWMTYGEAGTSRTAIGSGLICHGIPKGARVGLYFINRPEWTIVDNACSAYSYV 261 + G + TY + + L GI KG RV +Y E I AC+ V Sbjct: 103 ESDFGQVQLYTYAKLHNRVCRFANALRELGIKKGDRVIIYLPMLVEAVIAMQACARIGAV 162 Query: 262 SVPLYDTLGPDAVQFIVNHASVEAIFCVPQ--------TLSTLLSFITQMPCVRLIVVVG 417 ++ A++ + A + + L + +M C + V+ Sbjct: 163 HSVVFGGFSASALRDRIEDAEAKLVITANAGLRGGKIIPLKETVDEALEMGCKTIENVIV 222 Query: 418 GIDENMPSSPAAAGMEIITYSMLHRQGHMSPQPFRPPKPEDVATICYTSGTTGTPKGAVL 597 N+ +P G ++ + Q + ED I YTSG+TG PKG V Sbjct: 223 FHRVNI-DTPWKKGRDLWWNELTANQPAFCEPEWM--NAEDPLFILYTSGSTGKPKGIVH 279 Query: 598 SHANFI 615 S ++ Sbjct: 280 STGGYL 285
>ACS1_CANGA (Q6FLU2) Acetyl-coenzyme A synthetase 1 (EC 6.2.1.1) (Acetate--CoA| ligase 1) (Acyl-activating enzyme 1) Length = 704 Score = 32.0 bits (71), Expect = 1.6 Identities = 15/34 (44%), Positives = 19/34 (55%) Frame = +1 Query: 514 PFRPPKPEDVATICYTSGTTGTPKGAVLSHANFI 615 P P E + YTSG+TGTPKG S A ++ Sbjct: 296 PCEPVDSEHPLFLLYTSGSTGTPKGVQHSTAGYL 329
>S27A3_HUMAN (Q5K4L6) Long-chain fatty acid transport protein 3 (EC 6.2.1.-)| (Fatty acid transport protein 3) (FATP-3) (Very long-chain acyl-CoA synthetase homolog 3) (VLCS-3) (Solute carrier family 27 member 3) Length = 683 Score = 32.0 bits (71), Expect = 1.6 Identities = 40/166 (24%), Positives = 58/166 (34%), Gaps = 2/166 (1%) Frame = +1 Query: 124 AGTSRTAIGSGLICHGIPKGARVGLYFINRPE--WTIVDNACSAYSYVSVPLYDTLGPDA 297 AG A G G P GA V L PE W A + VP GP Sbjct: 149 AGGDGAARGGGAAAPLSP-GATVALLLPAGPEFLWLWFGLAKAGLRTAFVPTALRRGP-- 205 Query: 298 VQFIVNHASVEAIFCVPQTLSTLLSFITQMPCVRLIVVVGGIDENMPSSPAAAGMEIITY 477 + + A+ P+ L +L + + + L + G P + A +++ Sbjct: 206 LLHCLRSCGARALVLAPEFLESLEPDLPALRAMGLHLWAAG-----PGTHPAGISDLLAE 260 Query: 478 SMLHRQGHMSPQPFRPPKPEDVATICYTSGTTGTPKGAVLSHANFI 615 G + P D +TSGTTG PK A +SH + Sbjct: 261 VSAEVDGPVPGYLSSPQSITDTCLYIFTSGTTGLPKAARISHLKIL 306
>S27A1_RAT (P97849) Long-chain fatty acid transport protein 1 (EC 6.2.1.-)| (Fatty acid transport protein 1) (FATP-1) (Solute carrier family 27 member 1) Length = 646 Score = 31.6 bits (70), Expect = 2.0 Identities = 33/168 (19%), Positives = 66/168 (39%), Gaps = 1/168 (0%) Frame = +1 Query: 112 TYGEAGTSRTAIGSGLICHGIPKGARVGLYFINRPEWTIVDNACSAYSYVSVPLYDTLGP 291 T+ + T A+ + + G G V ++ RPE+ + + V+ L L Sbjct: 105 TFAQLDTYSNAVANLFLQLGFAPGDVVAVFLEGRPEFVGLWLGLAKAGVVAALLNVNLRR 164 Query: 292 DAVQFIVNHASVEAIFCVPQTLSTLLSFITQMPCVRLIVVVGGIDENMPSSPAAAGMEII 471 + + F + ++ +A+ + + + Q+ L G + P + + Sbjct: 165 EPLAFCLGTSAAKALIYGGEMAAAVAEVSEQLGKSLLKFCSGDL------GPESVLPDTQ 218 Query: 472 TYSMLHRQGHMSPQPFRPPKP-EDVATICYTSGTTGTPKGAVLSHANF 612 + + +P P K +D YTSGTTG PK A++ H+ + Sbjct: 219 LLDPMLAEAPTTPLAQAPGKGMDDRLFYIYTSGTTGLPKAAIVVHSRY 266
>S27A5_MOUSE (Q4LDG0) Bile acyl-CoA synthetase (EC 6.2.1.7) (BACS) (Bile acid| CoA ligase) (BA-CoA ligase) (BAL) (Cholate--CoA ligase) (Very long chain acyl-CoA synthetase-related protein) (VLACS-related) (VLACSR) (Fatty acid transport protein 5) (FATP-5) Length = 689 Score = 31.6 bits (70), Expect = 2.0 Identities = 14/24 (58%), Positives = 16/24 (66%) Frame = +1 Query: 544 ATICYTSGTTGTPKGAVLSHANFI 615 A +TSGTTG PK A+LSH I Sbjct: 289 AIFIFTSGTTGLPKPAILSHERVI 312
>PPS3_BACSU (P39847) Peptide synthetase 3| Length = 2555 Score = 31.6 bits (70), Expect = 2.0 Identities = 13/28 (46%), Positives = 18/28 (64%) Frame = +1 Query: 532 PEDVATICYTSGTTGTPKGAVLSHANFI 615 P +A I YTSG+TG PKG ++ + I Sbjct: 1644 PHSLAYIIYTSGSTGKPKGVMIEQRSVI 1671 Score = 31.6 bits (70), Expect = 2.0 Identities = 12/30 (40%), Positives = 19/30 (63%) Frame = +1 Query: 541 VATICYTSGTTGTPKGAVLSHANFIANVAG 630 +A + YTSG+TG PKG + H ++ + G Sbjct: 606 LAYVIYTSGSTGQPKGVAVEHRQAVSFLTG 635
>ACSA_CRYPV (Q27549) Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA| ligase) (Acyl-activating enzyme) Length = 694 Score = 31.6 bits (70), Expect = 2.0 Identities = 16/38 (42%), Positives = 19/38 (50%) Frame = +1 Query: 514 PFRPPKPEDVATICYTSGTTGTPKGAVLSHANFIANVA 627 P ED YTSG+TGTPKG S A ++ A Sbjct: 285 PLEDMDSEDPLFYLYTSGSTGTPKGVQHSTAGYLLYAA 322
>S27A5_HUMAN (Q9Y2P5) Bile acyl-CoA synthetase (EC 6.2.1.7) (BACS) (Bile acid| CoA ligase) (BA-CoA ligase) (BAL) (Cholate--CoA ligase) (Very long-chain acyl-CoA synthetase homolog 2) (VLCSH2) (VLCS-H2) (Very long chain acyl-CoA synthetase-related protein) Length = 690 Score = 31.2 bits (69), Expect = 2.6 Identities = 13/20 (65%), Positives = 15/20 (75%) Frame = +1 Query: 544 ATICYTSGTTGTPKGAVLSH 603 A YTSGTTG PK A+L+H Sbjct: 290 ALFIYTSGTTGLPKPAILTH 309
>ZCH14_MOUSE (Q8VIG0) Zinc finger CCHC domain-containing protein 14 (BDG-29)| Length = 956 Score = 31.2 bits (69), Expect = 2.6 Identities = 17/42 (40%), Positives = 23/42 (54%) Frame = +1 Query: 487 HRQGHMSPQPFRPPKPEDVATICYTSGTTGTPKGAVLSHANF 612 H+Q PQP PP V T C SG+ G+ G +S+AN+ Sbjct: 776 HQQPPAPPQPAPPPPGCIVCTSCGCSGSCGS-NGLTVSYANY 816
>PAX6_COTJA (P47238) Paired box protein Pax-6 (Pax-QNR)| Length = 416 Score = 31.2 bits (69), Expect = 2.6 Identities = 18/49 (36%), Positives = 23/49 (46%) Frame = +1 Query: 433 MPSSPAAAGMEIITYSMLHRQGHMSPQPFRPPKPEDVATICYTSGTTGT 579 +P+SP+ G TY+ H Q HM+ QP TSGTT T Sbjct: 352 LPTSPSVNGRSYDTYTPPHMQTHMNSQPMG------------TSGTTST 388
>MENE_STAAN (P63526) 2-succinylbenzoate--CoA ligase (EC 6.2.1.26) (OSB-CoA| synthetase) (o-succinylbenzoyl-CoA synthetase) Length = 492 Score = 31.2 bits (69), Expect = 2.6 Identities = 37/156 (23%), Positives = 65/156 (41%), Gaps = 7/156 (4%) Frame = +1 Query: 184 ARVGLYFINRPEWTIVDNACSAYSYVSVPLYDTLGPDAVQFIVNHASVEAIFC-VPQTLS 360 +RVGLY N + I+ +AC + + L P+ + + V+ IFC +P L Sbjct: 47 SRVGLYIDNSIQSIILIHACWLANIEIAMINTRLTPNEMTNQMRSIDVQLIFCTLPLELR 106 Query: 361 --TLLSFITQMPCVRLIVVVGGIDENMPSSPAAAGMEIITY----SMLHRQGHMSPQPFR 522 ++S R I G +D M + ++ ++L+ ++ Sbjct: 107 GFQIVSLDDIEFAGRDITTNGLLDNTMGIQYDTSNETVVPKESPSNILNTSFNL------ 160 Query: 523 PPKPEDVATICYTSGTTGTPKGAVLSHANFIANVAG 630 +D+A+I +TSGTTG K + N A+ G Sbjct: 161 ----DDIASIMFTSGTTGPQKAVPQTFRNHYASAIG 192
>MENE_STAAM (P63525) 2-succinylbenzoate--CoA ligase (EC 6.2.1.26) (OSB-CoA| synthetase) (o-succinylbenzoyl-CoA synthetase) Length = 492 Score = 31.2 bits (69), Expect = 2.6 Identities = 37/156 (23%), Positives = 65/156 (41%), Gaps = 7/156 (4%) Frame = +1 Query: 184 ARVGLYFINRPEWTIVDNACSAYSYVSVPLYDTLGPDAVQFIVNHASVEAIFC-VPQTLS 360 +RVGLY N + I+ +AC + + L P+ + + V+ IFC +P L Sbjct: 47 SRVGLYIDNSIQSIILIHACWLANIEIAMINTRLTPNEMTNQMRSIDVQLIFCTLPLELR 106 Query: 361 --TLLSFITQMPCVRLIVVVGGIDENMPSSPAAAGMEIITY----SMLHRQGHMSPQPFR 522 ++S R I G +D M + ++ ++L+ ++ Sbjct: 107 GFQIVSLDDIEFAGRDITTNGLLDNTMGIQYDTSNETVVPKESPSNILNTSFNL------ 160 Query: 523 PPKPEDVATICYTSGTTGTPKGAVLSHANFIANVAG 630 +D+A+I +TSGTTG K + N A+ G Sbjct: 161 ----DDIASIMFTSGTTGPQKAVPQTFRNHYASAIG 192
>ZCH14_HUMAN (Q8WYQ9) Zinc finger CCHC domain-containing protein 14 (BDG-29)| Length = 949 Score = 31.2 bits (69), Expect = 2.6 Identities = 17/42 (40%), Positives = 23/42 (54%) Frame = +1 Query: 487 HRQGHMSPQPFRPPKPEDVATICYTSGTTGTPKGAVLSHANF 612 H+Q PQP PP V T C SG+ G+ G +S+AN+ Sbjct: 769 HQQPPAPPQPAPPPPGCIVCTSCGCSGSCGS-SGLTVSYANY 809
>PAX6_CHICK (P47237) Paired box protein Pax-6 (Fragment)| Length = 216 Score = 31.2 bits (69), Expect = 2.6 Identities = 18/49 (36%), Positives = 23/49 (46%) Frame = +1 Query: 433 MPSSPAAAGMEIITYSMLHRQGHMSPQPFRPPKPEDVATICYTSGTTGT 579 +P+SP+ G TY+ H Q HM+ QP TSGTT T Sbjct: 152 LPTSPSVNGRSYDTYTPPHMQTHMNSQPMG------------TSGTTST 188
>PAX6_XENLA (P55864) Paired box protein Pax-6| Length = 422 Score = 31.2 bits (69), Expect = 2.6 Identities = 18/49 (36%), Positives = 23/49 (46%) Frame = +1 Query: 433 MPSSPAAAGMEIITYSMLHRQGHMSPQPFRPPKPEDVATICYTSGTTGT 579 +P+SP+ G TY+ H Q HM+ QP TSGTT T Sbjct: 358 LPTSPSVNGRSYDTYTPPHMQTHMNSQPMG------------TSGTTST 394
>PAX6_RAT (P63016) Paired box protein Pax-6 (Oculorhombin)| Length = 422 Score = 31.2 bits (69), Expect = 2.6 Identities = 18/49 (36%), Positives = 23/49 (46%) Frame = +1 Query: 433 MPSSPAAAGMEIITYSMLHRQGHMSPQPFRPPKPEDVATICYTSGTTGT 579 +P+SP+ G TY+ H Q HM+ QP TSGTT T Sbjct: 358 LPTSPSVNGRSYDTYTPPHMQTHMNSQPMG------------TSGTTST 394
>PAX6_MOUSE (P63015) Paired box protein Pax-6 (Oculorhombin)| Length = 422 Score = 31.2 bits (69), Expect = 2.6 Identities = 18/49 (36%), Positives = 23/49 (46%) Frame = +1 Query: 433 MPSSPAAAGMEIITYSMLHRQGHMSPQPFRPPKPEDVATICYTSGTTGT 579 +P+SP+ G TY+ H Q HM+ QP TSGTT T Sbjct: 358 LPTSPSVNGRSYDTYTPPHMQTHMNSQPMG------------TSGTTST 394
>PAX6_HUMAN (P26367) Paired box protein Pax-6 (Oculorhombin) (Aniridia type II| protein) Length = 422 Score = 31.2 bits (69), Expect = 2.6 Identities = 18/49 (36%), Positives = 23/49 (46%) Frame = +1 Query: 433 MPSSPAAAGMEIITYSMLHRQGHMSPQPFRPPKPEDVATICYTSGTTGT 579 +P+SP+ G TY+ H Q HM+ QP TSGTT T Sbjct: 358 LPTSPSVNGRSYDTYTPPHMQTHMNSQPMG------------TSGTTST 394
>S27A1_BOVIN (Q3ZKN0) Long-chain fatty acid transport protein 1 (EC 6.2.1.-)| (Fatty acid transport protein 1) (FATP-1) (Solute carrier family 27 member 1) Length = 646 Score = 30.8 bits (68), Expect = 3.5 Identities = 11/19 (57%), Positives = 15/19 (78%) Frame = +1 Query: 556 YTSGTTGTPKGAVLSHANF 612 YTSGTTG PK A++ H+ + Sbjct: 248 YTSGTTGLPKAAIIVHSRY 266
>ESYN_GIBPU (Q00868) Enniatin synthetase [Includes: N-methylcyclopeptide| synthetase (EC 6.3.2.-); S-adenosyl-L-methionine-dependent N-methyltransferase (EC 2.1.1.-)] (Fragment) Length = 983 Score = 30.8 bits (68), Expect = 3.5 Identities = 11/26 (42%), Positives = 17/26 (65%) Frame = +1 Query: 526 PKPEDVATICYTSGTTGTPKGAVLSH 603 P +A + +TSG+TG PKG ++ H Sbjct: 76 PSATSLAYVVFTSGSTGKPKGVMIEH 101
>LUCI_PHOPY (P08659) Luciferin 4-monooxygenase (EC 1.13.12.7) (Luciferase)| Length = 550 Score = 30.8 bits (68), Expect = 3.5 Identities = 24/102 (23%), Positives = 45/102 (44%), Gaps = 4/102 (3%) Frame = +1 Query: 310 VNHASVEAIFCVPQTLSTLLSFITQMPCVRLIVVVGGIDENMPSSPAAAGME-IITYSML 486 +N + +F + L +L+ ++P ++ I++ M S G + + T+ Sbjct: 118 MNISQPTVVFVSKKGLQKILNVQKKLPIIQKIII-------MDSKTDYQGFQSMYTFVTS 170 Query: 487 HRQGHMSPQPFRPP---KPEDVATICYTSGTTGTPKGAVLSH 603 H + F P + + +A I +SG+TG PKG L H Sbjct: 171 HLPPGFNEYDFVPESFDRDKTIALIMNSSGSTGLPKGVALPH 212
>ACSA_MOUSE (Q9QXG4) Acetyl-coenzyme A synthetase, cytoplasmic (EC 6.2.1.1)| (Acetate--CoA ligase) (Acyl-activating enzyme) (Acetyl-CoA synthetase) (ACS) (AceCS) (Acyl-CoA synthetase short-chain family member 2) Length = 701 Score = 30.8 bits (68), Expect = 3.5 Identities = 15/31 (48%), Positives = 19/31 (61%) Frame = +1 Query: 535 EDVATICYTSGTTGTPKGAVLSHANFIANVA 627 ED I YTSG+TG PKG V + ++ VA Sbjct: 308 EDPLFILYTSGSTGKPKGVVHTIGGYMLYVA 338
>ACSA_HUMAN (Q9NR19) Acetyl-coenzyme A synthetase, cytoplasmic (EC 6.2.1.1)| (Acetate--CoA ligase) (Acyl-activating enzyme) (Acetyl-CoA synthetase) (ACS) (AceCS) (Acyl-CoA synthetase short-chain family member 2) Length = 701 Score = 30.8 bits (68), Expect = 3.5 Identities = 15/31 (48%), Positives = 19/31 (61%) Frame = +1 Query: 535 EDVATICYTSGTTGTPKGAVLSHANFIANVA 627 ED I YTSG+TG PKG V + ++ VA Sbjct: 308 EDPLFILYTSGSTGKPKGVVHTVGGYMLYVA 338
>S27A1_MOUSE (Q60714) Long-chain fatty acid transport protein 1 (EC 6.2.1.-)| (Fatty acid transport protein 1) (FATP-1) (Solute carrier family 27 member 1) Length = 646 Score = 30.4 bits (67), Expect = 4.5 Identities = 11/19 (57%), Positives = 15/19 (78%) Frame = +1 Query: 556 YTSGTTGTPKGAVLSHANF 612 YTSGTTG PK A++ H+ + Sbjct: 248 YTSGTTGLPKAAIVVHSRY 266
>S27A1_HUMAN (Q6PCB7) Long-chain fatty acid transport protein 1 (EC 6.2.1.-)| (Fatty acid transport protein 1) (FATP-1) (Solute carrier family 27 member 1) Length = 646 Score = 30.4 bits (67), Expect = 4.5 Identities = 11/19 (57%), Positives = 15/19 (78%) Frame = +1 Query: 556 YTSGTTGTPKGAVLSHANF 612 YTSGTTG PK A++ H+ + Sbjct: 248 YTSGTTGLPKAAIVVHSRY 266
>FPG_NOCFA (Q5YS09) Formamidopyrimidine-DNA glycosylase (EC 3.2.2.23)| (Fapy-DNA glycosylase) (DNA-(apurinic or apyrimidinic site) lyase mutM) (EC 4.2.99.18) (AP lyase mutM) Length = 293 Score = 30.4 bits (67), Expect = 4.5 Identities = 15/39 (38%), Positives = 21/39 (53%), Gaps = 1/39 (2%) Frame = +1 Query: 55 RYLGTRVHADGTIGDYKWMTYGEAGTS-RTAIGSGLICH 168 R G RV A G Y W+T+ E G + TA+ + L+ H Sbjct: 46 RMTGRRVRAAQRRGKYLWLTFDEPGAADETALDAALVVH 84
>ENTF_ECOLI (P11454) Enterobactin synthetase component F (EC 2.7.7.-)| (Enterochelin synthase F) (Serine-activating enzyme) (Seryl-AMP ligase) Length = 1293 Score = 30.4 bits (67), Expect = 4.5 Identities = 14/41 (34%), Positives = 23/41 (56%), Gaps = 3/41 (7%) Frame = +1 Query: 502 MSPQ---PFRPPKPEDVATICYTSGTTGTPKGAVLSHANFI 615 ++PQ P + +P A I +TSG+TG PKG ++ + Sbjct: 581 LTPQGSAPLQLSQPHHTAYIIFTSGSTGRPKGVMVGQTAIV 621
>ENTF_ECO57 (Q8XBV9) Enterobactin synthetase component F (EC 2.7.7.-)| (Enterochelin synthase F) (Serine-activating enzyme) (Seryl-AMP ligase) Length = 1293 Score = 30.4 bits (67), Expect = 4.5 Identities = 14/41 (34%), Positives = 23/41 (56%), Gaps = 3/41 (7%) Frame = +1 Query: 502 MSPQ---PFRPPKPEDVATICYTSGTTGTPKGAVLSHANFI 615 ++PQ P + +P A I +TSG+TG PKG ++ + Sbjct: 581 LTPQGSAPLQLSQPHHTAYIIFTSGSTGRPKGVMVGQTAIV 621
>ENTF_SHIFL (P29698) Enterobactin synthetase component F (EC 2.7.7.-)| (Enterochelin synthase F) (Serine-activating enzyme) (Seryl-AMP ligase) Length = 1281 Score = 30.4 bits (67), Expect = 4.5 Identities = 14/41 (34%), Positives = 23/41 (56%), Gaps = 3/41 (7%) Frame = +1 Query: 502 MSPQ---PFRPPKPEDVATICYTSGTTGTPKGAVLSHANFI 615 ++PQ P + +P A I +TSG+TG PKG ++ + Sbjct: 585 LTPQGSAPLQLSQPHHTAYIIFTSGSTGRPKGVMVGQTAIV 625
>S27A4_PONPY (Q5RDY4) Long-chain fatty acid transport protein 4 (EC 6.2.1.-)| (Fatty acid transport protein 4) (FATP-4) (Solute carrier family 27 member 4) Length = 643 Score = 30.4 bits (67), Expect = 4.5 Identities = 11/19 (57%), Positives = 15/19 (78%) Frame = +1 Query: 556 YTSGTTGTPKGAVLSHANF 612 YTSGTTG PK A++ H+ + Sbjct: 245 YTSGTTGLPKAAIVVHSRY 263
>S27A4_MACFA (Q4R3Y4) Long-chain fatty acid transport protein 4 (EC 6.2.1.-)| (Fatty acid transport protein 4) (FATP-4) (Solute carrier family 27 member 4) Length = 643 Score = 30.4 bits (67), Expect = 4.5 Identities = 11/19 (57%), Positives = 15/19 (78%) Frame = +1 Query: 556 YTSGTTGTPKGAVLSHANF 612 YTSGTTG PK A++ H+ + Sbjct: 245 YTSGTTGLPKAAIVVHSRY 263
>S27A4_HUMAN (Q6P1M0) Long-chain fatty acid transport protein 4 (EC 6.2.1.-)| (Fatty acid transport protein 4) (FATP-4) (Solute carrier family 27 member 4) Length = 643 Score = 30.4 bits (67), Expect = 4.5 Identities = 11/19 (57%), Positives = 15/19 (78%) Frame = +1 Query: 556 YTSGTTGTPKGAVLSHANF 612 YTSGTTG PK A++ H+ + Sbjct: 245 YTSGTTGLPKAAIVVHSRY 263
>PRPE_ECOLI (P77495) Propionate--CoA ligase (EC 6.2.1.17) (Propionyl-CoA| synthetase) Length = 628 Score = 30.4 bits (67), Expect = 4.5 Identities = 40/172 (23%), Positives = 68/172 (39%), Gaps = 13/172 (7%) Frame = +1 Query: 112 TYGEAGTSRTAIGSGLICHGIPKGARVGLYFINRPEWTIVDNACSAYSYVSVPLYDTLGP 291 T+ + A+ S L G+ +G RV +Y E I AC+ + ++ Sbjct: 85 TFRQLHDEVNAVASMLRSLGVQRGDRVLVYMPMIAEAHITLLACARIGAIHSVVFGGFAS 144 Query: 292 DAVQFIVNHA------SVEA------IFCVPQTLSTLLSFITQMPCVRLIVVVGGIDENM 435 +V ++ A S +A I + L +S P L+V D + Sbjct: 145 HSVAARIDDAKPVLIVSADAGARGGKIIPYKKLLDDAISQAQHQPRHVLLV-----DRGL 199 Query: 436 PSSPAAAGMEIITYSMLHRQGHMSPQ-PFRPPKPEDVATICYTSGTTGTPKG 588 +G ++ S+ H+ H+ + P + + + I YTSGTTG PKG Sbjct: 200 AKMARVSGRDVDFASLRHQ--HIGARVPVAWLESNETSCILYTSGTTGKPKG 249
>FAT1_COCHE (O42633) Fatty acid transporter protein| Length = 643 Score = 30.4 bits (67), Expect = 4.5 Identities = 28/118 (23%), Positives = 50/118 (42%), Gaps = 13/118 (11%) Frame = +1 Query: 286 GPDAVQFIVNHASVEAIFCVPQTLSTLLSFITQMPCVRLI---VVVGGIDENMPSSPAAA 456 G ++ + ++ +++AI L+ L+ + C++L V+ ID P Sbjct: 132 GGNSAEHLMLWLALDAIGAATSFLNWNLTGAGLIHCIKLCECRFVIADIDIKANIEPCRG 191 Query: 457 GMEIITYSM-LHRQGHMSPQPFRPPKPED---------VATICYTSGTTGTPKGAVLS 600 +E ++ + +S P P P+ V + YTSGTTG PKG +S Sbjct: 192 ELEETGINIHYYDPSFISSLPNNTPIPDSRTENIELDSVRGLIYTSGTTGLPKGVFIS 249
>MENE_STAAR (Q6GFR0) 2-succinylbenzoate--CoA ligase (EC 6.2.1.26) (OSB-CoA| synthetase) (o-succinylbenzoyl-CoA synthetase) Length = 492 Score = 30.4 bits (67), Expect = 4.5 Identities = 34/156 (21%), Positives = 63/156 (40%), Gaps = 7/156 (4%) Frame = +1 Query: 184 ARVGLYFINRPEWTIVDNACSAYSYVSVPLYDTLGPDAVQFIVNHASVEAIFC-VPQTLS 360 +RVGLY N + I+ +AC + + L P+ + + V+ IFC +P L Sbjct: 47 SRVGLYIDNSIQSIILIHACWLANIEIAMINTRLTPNEMTNQMRSIDVQLIFCTLPLELR 106 Query: 361 TL-LSFITQMPCVRLIVVVGGIDENMPSSPAAAGMEIIT-----YSMLHRQGHMSPQPFR 522 + + + + G+ +N E + ++L+ ++ Sbjct: 107 GFQIVSLDDIEFAGTDITTNGLLDNTMGIQYDTSNETVVPKDSPSNILNTSFNL------ 160 Query: 523 PPKPEDVATICYTSGTTGTPKGAVLSHANFIANVAG 630 +D+A+I +TSGTTG K + N A+ G Sbjct: 161 ----DDIASIMFTSGTTGPQKAVPQTFRNHYASAIG 192
>S27A3_MOUSE (O88561) Long-chain fatty acid transport protein 3 (EC 6.2.1.-)| (Fatty acid transport protein 3) (FATP-3) (Solute carrier family 27 member 3) Length = 667 Score = 30.4 bits (67), Expect = 4.5 Identities = 15/35 (42%), Positives = 20/35 (57%), Gaps = 3/35 (8%) Frame = +1 Query: 508 PQPFRPPKPEDVATIC---YTSGTTGTPKGAVLSH 603 P P P+++ C +TSGTTG PK A +SH Sbjct: 252 PVPGYLSAPQNIMDTCLYIFTSGTTGLPKAARISH 286
>ACS1_KLULA (O60011) Acetyl-coenzyme A synthetase 1 (EC 6.2.1.1) (Acetate--CoA| ligase 1) (Acyl-activating enzyme 1) Length = 707 Score = 30.4 bits (67), Expect = 4.5 Identities = 15/39 (38%), Positives = 20/39 (51%) Frame = +1 Query: 499 HMSPQPFRPPKPEDVATICYTSGTTGTPKGAVLSHANFI 615 + S P P E + YTSG+TG PKG S A ++ Sbjct: 294 YKSYTPCEPVDSEHPLFLLYTSGSTGAPKGVQHSTAGYL 332
>DIP2C_HUMAN (Q9Y2E4) Disco-interacting protein 2 homolog C| Length = 1556 Score = 30.0 bits (66), Expect = 5.9 Identities = 39/173 (22%), Positives = 68/173 (39%), Gaps = 16/173 (9%) Frame = +1 Query: 136 RTAIGSGLICHGIPKGA-RVGLYFINRPEWTIVDNACSAYSYVSVPLYDTLGPDAVQFIV 312 R AI + L C + K A ++ + + R D+ Y P + I Sbjct: 995 RGAIANSLTCVQLHKRAEKIAVMLMERGHLQDGDHVALVY------------PPGIDLIA 1042 Query: 313 NHASVEAIFCVPQTLSTL--LSFITQMPCVRLIVVVGG---------IDENMPSSPAAAG 459 CVP T+ + T +P V++IV V I + + S AAA Sbjct: 1043 AFYGCLYAGCVPITVRPPHPQNIATTLPTVKMIVEVSRSACLMTTQLICKLLRSREAAAA 1102 Query: 460 MEIITYSMLHRQGHMSP----QPFRPPKPEDVATICYTSGTTGTPKGAVLSHA 606 +++ T+ ++ + Q +P P+ +A + ++ TTG G +SHA Sbjct: 1103 VDVRTWPLILDTDDLPKKRPAQICKPCNPDTLAYLDFSVSTTGMLAGVKMSHA 1155
>ACSA_XANCP (Q8P3L1) Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA| ligase) (Acyl-activating enzyme) Length = 647 Score = 30.0 bits (66), Expect = 5.9 Identities = 13/27 (48%), Positives = 18/27 (66%) Frame = +1 Query: 535 EDVATICYTSGTTGTPKGAVLSHANFI 615 ED I YTSG+TG PKG + + A ++ Sbjct: 255 EDPLFILYTSGSTGKPKGVLHTTAGYL 281
>ACSA_XANAC (Q8PF09) Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA| ligase) (Acyl-activating enzyme) Length = 647 Score = 30.0 bits (66), Expect = 5.9 Identities = 13/27 (48%), Positives = 18/27 (66%) Frame = +1 Query: 535 EDVATICYTSGTTGTPKGAVLSHANFI 615 ED I YTSG+TG PKG + + A ++ Sbjct: 255 EDPLFILYTSGSTGKPKGVLHTTAGYL 281
>S27A2_RAT (P97524) Very-long-chain acyl-CoA synthetase (EC 6.2.1.-) (VLCS)| (Very-long-chain-fatty-acid-CoA ligase) (VLACS) (THCA-CoA ligase) (Fatty-acid-coenzyme A ligase, very long-chain 1) (Long-chain-fatty-acid--CoA ligase) (EC 6.2.1.3) (Fatty acid tr Length = 620 Score = 30.0 bits (66), Expect = 5.9 Identities = 12/20 (60%), Positives = 14/20 (70%) Frame = +1 Query: 544 ATICYTSGTTGTPKGAVLSH 603 A YTSGTTG PK A ++H Sbjct: 220 AVYIYTSGTTGLPKAATINH 239
>S27A2_MOUSE (O35488) Very-long-chain acyl-CoA synthetase (EC 6.2.1.-) (VLCS)| (Very-long-chain-fatty-acid-CoA ligase) (VLACS) (THCA-CoA ligase) (Fatty-acid-coenzyme A ligase, very long-chain 1) (Long-chain-fatty-acid--CoA ligase) (EC 6.2.1.3) (Fatty acid Length = 620 Score = 30.0 bits (66), Expect = 5.9 Identities = 12/20 (60%), Positives = 14/20 (70%) Frame = +1 Query: 544 ATICYTSGTTGTPKGAVLSH 603 A YTSGTTG PK A ++H Sbjct: 220 AVYIYTSGTTGLPKAATINH 239
>S27A2_HUMAN (O14975) Very-long-chain acyl-CoA synthetase (EC 6.2.1.-) (VLCS)| (Very-long-chain-fatty-acid-CoA ligase) (VLACS) (THCA-CoA ligase) (Fatty-acid-coenzyme A ligase, very long-chain 1) (Long-chain-fatty-acid--CoA ligase) (EC 6.2.1.3) (Fatty acid Length = 620 Score = 30.0 bits (66), Expect = 5.9 Identities = 12/20 (60%), Positives = 15/20 (75%) Frame = +1 Query: 544 ATICYTSGTTGTPKGAVLSH 603 A YTSGTTG PK A+++H Sbjct: 220 ALYIYTSGTTGLPKAAMITH 239
>ACSA_VIBCH (Q9KV59) Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA| ligase) (Acyl-activating enzyme) Length = 649 Score = 30.0 bits (66), Expect = 5.9 Identities = 13/29 (44%), Positives = 18/29 (62%) Frame = +1 Query: 529 KPEDVATICYTSGTTGTPKGAVLSHANFI 615 K ED I YTSG+TG PKG + + ++ Sbjct: 254 KAEDPLFILYTSGSTGKPKGVLHTTGGYL 282
>ACS1_ASHGO (Q758X0) Acetyl-coenzyme A synthetase 1 (EC 6.2.1.1) (Acetate--CoA| ligase 1) (Acyl-activating enzyme 1) Length = 694 Score = 30.0 bits (66), Expect = 5.9 Identities = 14/34 (41%), Positives = 18/34 (52%) Frame = +1 Query: 514 PFRPPKPEDVATICYTSGTTGTPKGAVLSHANFI 615 P P E + YTSG+TG PKG S A ++ Sbjct: 286 PCEPVDSEHPLFLLYTSGSTGAPKGVQHSTAGYL 319
>OLR1_MOUSE (Q9EQ09) Oxidized low-density lipoprotein receptor 1 (Ox-LDL| receptor 1) (Lectin-type oxidized LDL receptor 1) (Lectin-like oxidized LDL receptor 1) (Lectin-like oxLDL receptor 1) (LOX-1) [Contains: Oxidized low-density lipoprotein receptor 1, Length = 363 Score = 29.6 bits (65), Expect = 7.7 Identities = 15/45 (33%), Positives = 21/45 (46%) Frame = +3 Query: 66 YKGPCRWNNWRLQMDDLWRSWHKQDCNRFWPYLSWNT*RRTCWSV 200 + GPC +W WHK++C F SW R+TC S+ Sbjct: 231 FSGPCP-QDWL---------WHKENCYLFHGPFSWEKNRQTCQSL 265
>ACSA_COPCI (O13440) Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA| ligase) (Acyl-activating enzyme) Length = 661 Score = 29.6 bits (65), Expect = 7.7 Identities = 13/27 (48%), Positives = 17/27 (62%) Frame = +1 Query: 535 EDVATICYTSGTTGTPKGAVLSHANFI 615 ED I YTSG+TG PKG V + ++ Sbjct: 262 EDPLFILYTSGSTGKPKGVVHTTGGYL 288
>LYS2_SCHPO (P40976) L-aminoadipate-semialdehyde dehydrogenase (EC 1.2.1.31)| (Alpha-aminoadipate reductase) (Alpha-AR) Length = 1419 Score = 29.6 bits (65), Expect = 7.7 Identities = 45/199 (22%), Positives = 73/199 (36%), Gaps = 15/199 (7%) Frame = +1 Query: 52 CRYLGTRVHADGTIGDYKWMTYGEAGTSRTAIGSGLICHGIPKGARVGLYFINRPEWTI- 228 C + V D + Y TY + S + L+ +GI +G V +Y + + Sbjct: 297 CIVVTPSVTIDAPVTSY---TYRQIDESSNILAHHLVKNGIERGDVVMVYAYRGVDLVVA 353 Query: 229 ---VDNACSAYSYVSVPLYDTLGPDAVQFIVNHASVEAIFCVPQTLSTL----------- 366 V A + +S + P Y P A Q I + V + L Sbjct: 354 VMGVLKAGATFSVID-PAY----PPARQIIYLSVAKPRALVVLEDAGVLSPTVVEYVEKS 408 Query: 367 LSFITQMPCVRLIVVVGGIDENMPSSPAAAGMEIITYSMLHRQGHMSPQPFRPPKPEDVA 546 L T +P ++L D ++ + G + I +LH + S Q P+ Sbjct: 409 LELKTYVPALKLAK-----DGSLTGGSVSKGADDILQHVLHLK---SEQTGVVVGPDSTP 460 Query: 547 TICYTSGTTGTPKGAVLSH 603 T+ +TSG+ G PKG H Sbjct: 461 TLSFTSGSEGIPKGVKGRH 479 Database: uniprot_sprot.fasta Posted date: May 25, 2006 5:36 PM Number of letters in database: 80,573,946 Number of sequences in database: 219,361 Lambda K H 0.318 0.135 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 91,814,256 Number of Sequences: 219361 Number of extensions: 2011913 Number of successful extensions: 5592 Number of sequences better than 10.0: 242 Number of HSP's better than 10.0 without gapping: 5272 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 5537 length of database: 80,573,946 effective HSP length: 107 effective length of database: 57,102,319 effective search space used: 5824436538 frameshift window, decay const: 50, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
