ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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| Clone Name | bags9g15 |
|---|---|
| Clone Library Name | barley_pub |
>TRIPC_HUMAN (Q14669) Thyroid receptor-interacting protein 12 (TRIP12)| Length = 1992 Score = 139 bits (349), Expect = 8e-33 Identities = 83/200 (41%), Positives = 119/200 (59%), Gaps = 6/200 (3%) Frame = +1 Query: 13 IQAPLGLFPRPWPSNVDTSEGSRFLKVVEYFRLVGRVVAKVLQDGRLLDLPLSTAFYKLI 192 IQ GLF P+ T++ + KV FR +G+++AK + D RL+DLPL FYK + Sbjct: 1670 IQNLQGLFALPFGR---TAKPAHIAKVKMKFRFLGKLMAKAIMDFRLVDLPLGLPFYKWM 1726 Query: 193 LGQELDL--FDIISFDAELGKTLQELQVLVERKRFFES--SCGKDQLKVA--DLRFRGAP 354 L QE L D+ D + +++ L+ +V +K+ E S K+ L+ A L G Sbjct: 1727 LRQETSLTSHDLFDIDPVVARSVYHLEDIVRQKKRLEQDKSQTKESLQYALETLTMNGCS 1786 Query: 355 IEDLCLDFTLPGFPDYVLKEGEQNTIVNIHNLEEYVSLVVDATLKSGIMKQVEAFRSGFS 534 +EDL LDFTLPGFP+ LK+G ++ V IHNLEEY+ LV+ L G+ +Q ++FR GF Sbjct: 1787 VEDLGLDFTLPGFPNIELKKGGKDIPVTIHNLEEYLRLVIFWALNEGVSRQFDSFRDGFE 1846 Query: 535 QVFDISSLQIFSPQELDYLI 594 VF +S LQ F P+ELD L+ Sbjct: 1847 SVFPLSHLQYFYPEELDQLL 1866
>YDE1_SCHPO (Q10435) Probable ubiquitin fusion degradation protein C12B10.01c| Length = 1647 Score = 90.1 bits (222), Expect = 4e-18 Identities = 60/185 (32%), Positives = 97/185 (52%) Frame = +1 Query: 28 GLFPRPWPSNVDTSEGSRFLKVVEYFRLVGRVVAKVLQDGRLLDLPLSTAFYKLILGQEL 207 GLFP P P + E R K+ +F L G+ VA+ + D R++ + + F+ + L Sbjct: 1352 GLFPSPIPLLGSSPENER--KISLFFAL-GQFVARSIYDSRIISIQFNPLFFARNI--PL 1406 Query: 208 DLFDIISFDAELGKTLQELQVLVERKRFFESSCGKDQLKVADLRFRGAPIEDLCLDFTLP 387 + + D L +L+ L+ L+ K + D++ +EDL LDFTLP Sbjct: 1407 TISSVAKVDKGLANSLRYLEKLIPGKNPTNAE--------TDIK-----LEDLHLDFTLP 1453 Query: 388 GFPDYVLKEGEQNTIVNIHNLEEYVSLVVDATLKSGIMKQVEAFRSGFSQVFDISSLQIF 567 GFP L +T V N+ +Y++ V+D T+ G+ +Q+EAF++GFS VF +SLQ+ Sbjct: 1454 GFPSIELIPDGASTPVTTFNVSDYLNYVIDYTVGKGVQQQLEAFQNGFSSVFPYTSLQVL 1513 Query: 568 SPQEL 582 + EL Sbjct: 1514 TEHEL 1518
>UPL2_ARATH (Q8H0T4) E3 ubiquitin protein ligase UPL2 (EC 6.3.2.-)| (Ubiquitin-protein ligase 2) Length = 3658 Score = 84.0 bits (206), Expect = 3e-16 Identities = 57/167 (34%), Positives = 82/167 (49%) Frame = +1 Query: 94 VEYFRLVGRVVAKVLQDGRLLDLPLSTAFYKLILGQELDLFDIISFDAELGKTLQELQVL 273 + YF+ VGR+VAK L DG+LLD+ + +FYK ILG ++ DI + D + K L+ L Sbjct: 3382 LSYFKFVGRMVAKALFDGQLLDVYFTRSFYKHILGVKVTYHDIEAVDPDYYKNLKWL--- 3438 Query: 274 VERKRFFESSCGKDQLKVADLRFRGAPIEDLCLDFTLPGFPDYVLKEGEQNTIVNIHNLE 453 D + DL F E+ + + DY LK G +N V Sbjct: 3439 ----------LENDVSDILDLTFSMDADEEKHILYEKTEVTDYELKPGGRNIRVTEETKH 3488 Query: 454 EYVSLVVDATLKSGIMKQVEAFRSGFSQVFDISSLQIFSPQELDYLI 594 EYV LV D L S I Q+ AF G +++ + IF+ +EL+ LI Sbjct: 3489 EYVDLVADHILTSAIRPQINAFLEGLNELIPRELVSIFNDKELELLI 3535
>UPL1_ARATH (Q8GY23) E3 ubiquitin protein ligase UPL1 (EC 6.3.2.-)| (Ubiquitin-protein ligase 1) Length = 3684 Score = 82.4 bits (202), Expect = 9e-16 Identities = 56/167 (33%), Positives = 82/167 (49%) Frame = +1 Query: 94 VEYFRLVGRVVAKVLQDGRLLDLPLSTAFYKLILGQELDLFDIISFDAELGKTLQELQVL 273 + YF+ VGR+VAK L DG+LLD+ + +FYK ILG ++ DI + D + K L+ L Sbjct: 3405 LSYFKFVGRMVAKALFDGQLLDVYFTRSFYKHILGVKVTYHDIEAVDPDYYKNLKWL--- 3461 Query: 274 VERKRFFESSCGKDQLKVADLRFRGAPIEDLCLDFTLPGFPDYVLKEGEQNTIVNIHNLE 453 D + DL F E+ + + DY LK G +N V Sbjct: 3462 ----------LENDVSDILDLTFSMDADEEKHILYEKTEVTDYELKPGGRNIRVTEETKH 3511 Query: 454 EYVSLVVDATLKSGIMKQVEAFRSGFSQVFDISSLQIFSPQELDYLI 594 EYV LV L + I Q+ AF GF+++ + IF+ +EL+ LI Sbjct: 3512 EYVDLVAGHILTNAIRPQINAFLEGFNELIPRELVSIFNDKELELLI 3558
>UFD4_YEAST (P33202) Ubiquitin fusion degradation protein 4 (UB fusion protein 4)| Length = 1483 Score = 80.5 bits (197), Expect = 3e-15 Identities = 61/184 (33%), Positives = 82/184 (44%) Frame = +1 Query: 31 LFPRPWPSNVDTSEGSRFLKVVEYFRLVGRVVAKVLQDGRLLDLPLSTAFYKLILGQELD 210 LFP P + S KV+E F +G VA+ L D R+LD S F++L+ Sbjct: 1186 LFPEP------LNPFSNNEKVIELFGYLGTFVARSLLDNRILDFRFSKVFFELLHRMSTP 1239 Query: 211 LFDIISFDAELGKTLQELQVLVERKRFFESSCGKDQLKVADLRFRGAPIEDLCLDFTLPG 390 + D E + EL + K KD +E L L FT+PG Sbjct: 1240 NVTTVPSDVETCLLMIELVDPLLAKSLKYIVANKDD---------NMTLESLSLTFTVPG 1290 Query: 391 FPDYVLKEGEQNTIVNIHNLEEYVSLVVDATLKSGIMKQVEAFRSGFSQVFDISSLQIFS 570 D L G N +N N+EEY+ V+D L GI KQ++AF GFS+VF + I Sbjct: 1291 NDDIELIPGGCNKSLNSSNVEEYIHGVIDQILGKGIEKQLKAFIEGFSKVFSYERMLILF 1350 Query: 571 PQEL 582 P EL Sbjct: 1351 PDEL 1354
>WWP2_MOUSE (Q9DBH0) NEDD4-like E3 ubiquitin-protein ligase WWP2 (EC 6.3.2.-) (WW| domain-containing protein 2) Length = 870 Score = 72.8 bits (177), Expect = 7e-13 Identities = 47/165 (28%), Positives = 77/165 (46%) Frame = +1 Query: 100 YFRLVGRVVAKVLQDGRLLDLPLSTAFYKLILGQELDLFDIISFDAELGKTLQELQVLVE 279 YFR +GR +A L G+ +D + FYK +L + L D+ S D E ++ V ++ Sbjct: 604 YFRFIGRFIAMALYHGKFIDTGFTLPFYKRMLNKRPTLKDLESIDPEFYNSI----VWIK 659 Query: 280 RKRFFESSCGKDQLKVADLRFRGAPIEDLCLDFTLPGFPDYVLKEGEQNTIVNIHNLEEY 459 E CG + + D+ G + LKEG +N V N EEY Sbjct: 660 ENNLEE--CGLELFFIQDMEILGK-------------VTTHELKEGGENIRVTEENKEEY 704 Query: 460 VSLVVDATLKSGIMKQVEAFRSGFSQVFDISSLQIFSPQELDYLI 594 + L+ D G+ +Q +AF GF++V + L+ F +EL+ ++ Sbjct: 705 IMLLTDWRFTRGVEEQTKAFLDGFNEVAPLEWLRYFDEKELELML 749
>ITCH_MOUSE (Q8C863) Itchy E3 ubiquitin protein ligase (EC 6.3.2.-)| Length = 864 Score = 72.4 bits (176), Expect = 9e-13 Identities = 49/167 (29%), Positives = 76/167 (45%) Frame = +1 Query: 94 VEYFRLVGRVVAKVLQDGRLLDLPLSTAFYKLILGQELDLFDIISFDAELGKTLQELQVL 273 ++YFR +GR +A L G+ +D S FYK IL + + L D+ S D E +L + Sbjct: 596 LKYFRFIGRFIAMALFHGKFIDTGFSLPFYKRILNKPVGLKDLESIDPEFYNSL----IW 651 Query: 274 VERKRFFESSCGKDQLKVADLRFRGAPIEDLCLDFTLPGFPDYVLKEGEQNTIVNIHNLE 453 V+ E CG + D G + LK N +V N E Sbjct: 652 VKENNIEE--CGLEMYFSVDKEILGE-------------IKSHDLKPNGGNILVTEENKE 696 Query: 454 EYVSLVVDATLKSGIMKQVEAFRSGFSQVFDISSLQIFSPQELDYLI 594 EY+ +V + L G+ +Q +AF GF+++ LQ F +EL+ L+ Sbjct: 697 EYIRMVAEWRLSRGVEEQTQAFFEGFNEILPQQYLQYFDAKELEVLL 743
>WWP2_HUMAN (O00308) NEDD4-like E3 ubiquitin-protein ligase WWP2 (EC 6.3.2.-) (WW| domain-containing protein 2) (Atrophin-1-interacting protein 2) (AIP2) Length = 870 Score = 70.5 bits (171), Expect = 4e-12 Identities = 46/165 (27%), Positives = 77/165 (46%) Frame = +1 Query: 100 YFRLVGRVVAKVLQDGRLLDLPLSTAFYKLILGQELDLFDIISFDAELGKTLQELQVLVE 279 YFR +GR +A L G+ +D + FYK +L + L D+ S D E ++ V ++ Sbjct: 604 YFRFIGRFIAMALYHGKFIDTGFTLPFYKRMLNKRPTLKDLESIDPEFYNSI----VWIK 659 Query: 280 RKRFFESSCGKDQLKVADLRFRGAPIEDLCLDFTLPGFPDYVLKEGEQNTIVNIHNLEEY 459 E CG + + D+ G + LKEG ++ V N EEY Sbjct: 660 ENNLEE--CGLELYFIQDMEILGK-------------VTTHELKEGGESIRVTEENKEEY 704 Query: 460 VSLVVDATLKSGIMKQVEAFRSGFSQVFDISSLQIFSPQELDYLI 594 + L+ D G+ +Q +AF GF++V + L+ F +EL+ ++ Sbjct: 705 IMLLTDWRFTRGVEEQTKAFLDGFNEVAPLEWLRYFDEKELELML 749
>WWP1_MOUSE (Q8BZZ3) NEDD4-like E3 ubiquitin-protein ligase WWP1 (EC 6.3.2.-) (WW| domain-containing protein 1) Length = 918 Score = 70.1 bits (170), Expect = 5e-12 Identities = 45/167 (26%), Positives = 76/167 (45%) Frame = +1 Query: 94 VEYFRLVGRVVAKVLQDGRLLDLPLSTAFYKLILGQELDLFDIISFDAELGKTLQELQVL 273 + YF +GR +A L G+ +D S FYK +L ++L + D+ S D E +L + Sbjct: 650 LSYFCFIGRFIAMALFHGKFIDTGFSLPFYKRMLSKKLTIKDLESIDTEFYNSL----IW 705 Query: 274 VERKRFFESSCGKDQLKVADLRFRGAPIEDLCLDFTLPGFPDYVLKEGEQNTIVNIHNLE 453 + E CG + D+ G + LK G N +V N + Sbjct: 706 IRDNNIEE--CGLEMYFSVDMEILGK-------------VTSHDLKLGGSNILVTEENKD 750 Query: 454 EYVSLVVDATLKSGIMKQVEAFRSGFSQVFDISSLQIFSPQELDYLI 594 EY+ L+ + G+ +Q +AF GF++V + LQ F +EL+ ++ Sbjct: 751 EYIGLMTEWRFSRGVQEQTKAFLDGFNEVVPLQWLQYFDEKELEVML 797
>WWP1_HUMAN (Q9H0M0) NEDD4-like E3 ubiquitin-protein ligase WWP1 (EC 6.3.2.-) (WW| domain-containing protein 1) (Atropin-1-interacting protein 5) (AIP5) Length = 922 Score = 70.1 bits (170), Expect = 5e-12 Identities = 45/167 (26%), Positives = 76/167 (45%) Frame = +1 Query: 94 VEYFRLVGRVVAKVLQDGRLLDLPLSTAFYKLILGQELDLFDIISFDAELGKTLQELQVL 273 + YF +GR +A L G+ +D S FYK +L ++L + D+ S D E +L + Sbjct: 654 LSYFCFIGRFIAMALFHGKFIDTGFSLPFYKRMLSKKLTIKDLESIDTEFYNSL----IW 709 Query: 274 VERKRFFESSCGKDQLKVADLRFRGAPIEDLCLDFTLPGFPDYVLKEGEQNTIVNIHNLE 453 + E CG + D+ G + LK G N +V N + Sbjct: 710 IRDNNIEE--CGLEMYFSVDMEILGK-------------VTSHDLKLGGSNILVTEENKD 754 Query: 454 EYVSLVVDATLKSGIMKQVEAFRSGFSQVFDISSLQIFSPQELDYLI 594 EY+ L+ + G+ +Q +AF GF++V + LQ F +EL+ ++ Sbjct: 755 EYIGLMTEWRFSRGVQEQTKAFLDGFNEVVPLQWLQYFDEKELEVML 801
>ITCH_HUMAN (Q96J02) Itchy homolog E3 ubiquitin protein ligase (EC 6.3.2.-)| (Itch) (Atrophin-1-interacting protein 4) (AIP4) (NFE2-associated polypeptide 1) (NAPP1) Length = 903 Score = 69.7 bits (169), Expect = 6e-12 Identities = 48/167 (28%), Positives = 75/167 (44%) Frame = +1 Query: 94 VEYFRLVGRVVAKVLQDGRLLDLPLSTAFYKLILGQELDLFDIISFDAELGKTLQELQVL 273 ++YFR +GR +A L G+ +D S FYK IL + + L D+ S D E +L + Sbjct: 635 LKYFRFIGRFIAMALFHGKFIDTGFSLPFYKRILNKPVGLKDLESIDPEFYNSL----IW 690 Query: 274 VERKRFFESSCGKDQLKVADLRFRGAPIEDLCLDFTLPGFPDYVLKEGEQNTIVNIHNLE 453 V+ E C + D G + LK N +V N E Sbjct: 691 VKENNIEE--CDLEMYFSVDKEILGE-------------IKSHDLKPNGGNILVTEENKE 735 Query: 454 EYVSLVVDATLKSGIMKQVEAFRSGFSQVFDISSLQIFSPQELDYLI 594 EY+ +V + L G+ +Q +AF GF+++ LQ F +EL+ L+ Sbjct: 736 EYIRMVAEWRLSRGVEEQTQAFFEGFNEILPQQYLQYFDAKELEVLL 782
>TOM1_NEUCR (Q9P4Z1) E3 ubiquitin protein ligase TOM1-like protein (EC 6.3.2.-)| Length = 4065 Score = 69.7 bits (169), Expect = 6e-12 Identities = 50/171 (29%), Positives = 82/171 (47%), Gaps = 6/171 (3%) Frame = +1 Query: 100 YFRLVGRVVAKVLQDGRLLDLPLSTAFYKLILGQELDLFDIISFDAELGKTLQEL----- 264 +F+ +GR++ K L +GRLL+ S A YK ILG+ + + D+ SFD + K+L + Sbjct: 3798 FFKFIGRIIGKALYEGRLLECYFSRAVYKRILGKPVSVKDMESFDPDYYKSLVWMLENDI 3857 Query: 265 -QVLVERKRFFESSCGKDQLKVADLRFRGAPIEDLCLDFTLPGFPDYVLKEGEQNTIVNI 441 ++ E + G ++KV D L E +N V Sbjct: 3858 TDIITETFSVEDDVFG--EVKVVD------------------------LIENGRNIPVTE 3891 Query: 442 HNLEEYVSLVVDATLKSGIMKQVEAFRSGFSQVFDISSLQIFSPQELDYLI 594 N EYV L+V+ L + + Q++AF +GF ++ + IF+ QEL+ LI Sbjct: 3892 ENKHEYVRLIVEHKLITSVKDQMKAFLTGFHEIIPEELIAIFNEQELELLI 3942
>HUWE1_HUMAN (Q7Z6Z7) HECT, UBA and WWE domain-containing protein 1 (EC 6.3.2.-)| (E3 ubiquitin protein ligase URE-B1) (Mcl-1 ubiquitin ligase E3) (Mule) (ARF-binding protein 1) (ARF-BP1) Length = 4374 Score = 68.9 bits (167), Expect = 1e-11 Identities = 54/168 (32%), Positives = 79/168 (47%), Gaps = 1/168 (0%) Frame = +1 Query: 94 VEYFRLVGRVVAKVLQDGRLLDLPLSTAFYKLILGQELDLFDIISFDAELGKTLQELQVL 273 + YF+ VGR+VAK + D RLL+ + +FYK ILG+ + D+ S D Q L L Sbjct: 4104 LSYFKFVGRIVAKAVYDNRLLECYFTRSFYKHILGKSVRYTDMESEDYHF---YQGLVYL 4160 Query: 274 VERKRFFESSCGKDQLKVADLR-FRGAPIEDLCLDFTLPGFPDYVLKEGEQNTIVNIHNL 450 +E S+ G D +++ F + DL K N +V N Sbjct: 4161 LEND---VSTLGYDLTFSTEVQEFGVCEVRDL--------------KPNGANILVTEENK 4203 Query: 451 EEYVSLVVDATLKSGIMKQVEAFRSGFSQVFDISSLQIFSPQELDYLI 594 +EYV LV + I KQ+ AF GF ++ + IF+ QEL+ LI Sbjct: 4204 KEYVHLVCQMRMTGAIRKQLAAFLEGFYEIIPKRLISIFTEQELELLI 4251
>HUWE1_MOUSE (Q7TMY8) HECT, UBA and WWE domain-containing protein 1 (EC 6.3.2.-)| (E3 ubiquitin protein ligase URE-B1) (E3Histone) Length = 4377 Score = 68.9 bits (167), Expect = 1e-11 Identities = 54/168 (32%), Positives = 79/168 (47%), Gaps = 1/168 (0%) Frame = +1 Query: 94 VEYFRLVGRVVAKVLQDGRLLDLPLSTAFYKLILGQELDLFDIISFDAELGKTLQELQVL 273 + YF+ VGR+VAK + D RLL+ + +FYK ILG+ + D+ S D Q L L Sbjct: 4107 LSYFKFVGRIVAKAVYDNRLLECYFTRSFYKHILGKSVRYTDMESEDYHF---YQGLVYL 4163 Query: 274 VERKRFFESSCGKDQLKVADLR-FRGAPIEDLCLDFTLPGFPDYVLKEGEQNTIVNIHNL 450 +E S+ G D +++ F + DL K N +V N Sbjct: 4164 LEND---VSTLGYDLTFSTEVQEFGVCEVRDL--------------KPNGANILVTEENK 4206 Query: 451 EEYVSLVVDATLKSGIMKQVEAFRSGFSQVFDISSLQIFSPQELDYLI 594 +EYV LV + I KQ+ AF GF ++ + IF+ QEL+ LI Sbjct: 4207 KEYVHLVCQMRMTGAIRKQLAAFLEGFYEIIPKRLISIFTEQELELLI 4254
>HUWE1_RAT (P51593) HECT, UBA and WWE domain-containing protein 1 (EC 6.3.2.-)| (E3 ubiquitin protein ligase URE-B1) (Upstream regulatory element-binding protein 1) (Fragment) Length = 322 Score = 68.9 bits (167), Expect = 1e-11 Identities = 54/168 (32%), Positives = 79/168 (47%), Gaps = 1/168 (0%) Frame = +1 Query: 94 VEYFRLVGRVVAKVLQDGRLLDLPLSTAFYKLILGQELDLFDIISFDAELGKTLQELQVL 273 + YF+ VGR+VAK + D RLL+ + +FYK ILG+ + D+ S D Q L L Sbjct: 52 LSYFKFVGRIVAKAVYDNRLLECYFTRSFYKHILGKSVRYTDMESEDYHF---YQGLVYL 108 Query: 274 VERKRFFESSCGKDQLKVADLR-FRGAPIEDLCLDFTLPGFPDYVLKEGEQNTIVNIHNL 450 +E S+ G D +++ F + DL K N +V N Sbjct: 109 LEND---VSTLGYDLTFSTEVQEFGVCEVRDL--------------KPNGANILVTEENK 151 Query: 451 EEYVSLVVDATLKSGIMKQVEAFRSGFSQVFDISSLQIFSPQELDYLI 594 +EYV LV + I KQ+ AF GF ++ + IF+ QEL+ LI Sbjct: 152 KEYVHLVCQMRMTGAIRKQLAAFLEGFYEIIPKRLISIFTEQELELLI 199
>NEDD4_DROME (Q9VVI3) E3 ubiquitin-protein ligase Nedd-4 (EC 6.3.2.-) (DNedd4)| Length = 1007 Score = 67.8 bits (164), Expect = 2e-11 Identities = 44/168 (26%), Positives = 81/168 (48%), Gaps = 1/168 (0%) Frame = +1 Query: 94 VEYFRLVGRVVAKVLQDGRLLDLPLSTAFYKLILGQELDLFDIISFDAELGKTLQELQVL 273 + YF+ +GR+ + G+LLD FYK++L + +DL D+ S D E +L ++ Sbjct: 739 LSYFKFIGRIAGMAVYHGKLLDAFFIRPFYKMMLQKPIDLKDMESVDTEYYNSLMWIK-- 796 Query: 274 VERKRFFESSCGKDQLKVADLRFRGAPIEDLCLDFTLPGFPD-YVLKEGEQNTIVNIHNL 450 ++ ++ +L F CLD + G + LK G N V N Sbjct: 797 ------------ENDPRILELTF--------CLDEDVFGQKSQHELKPGGANIDVTNENK 836 Query: 451 EEYVSLVVDATLKSGIMKQVEAFRSGFSQVFDISSLQIFSPQELDYLI 594 +EY+ LV++ + + +Q+ +F GF + ++ ++IF EL+ L+ Sbjct: 837 DEYIKLVIEWRFVARVKEQMSSFLDGFGSIIPLNLIKIFDEHELELLM 884
>SUDX_DROME (Q9Y0H4) E3 ubiquitin-protein ligase suppressor of deltex (EC| 6.3.2.-) Length = 949 Score = 64.7 bits (156), Expect = 2e-10 Identities = 45/167 (26%), Positives = 78/167 (46%) Frame = +1 Query: 94 VEYFRLVGRVVAKVLQDGRLLDLPLSTAFYKLILGQELDLFDIISFDAELGKTLQELQVL 273 ++YF+ +GR +A L GR + + FYK +L ++L + DI + D E +L + Sbjct: 681 LQYFKFIGRFIAMALYHGRFIYSGFTMPFYKRMLNKKLTIKDIETIDPEFYNSL----IW 736 Query: 274 VERKRFFESSCGKDQLKVADLRFRGAPIEDLCLDFTLPGFPDYVLKEGEQNTIVNIHNLE 453 V+ E CG + D G I + LKE + V N E Sbjct: 737 VKDNNIDE--CGLELWFSVDFEVLGQIIH-------------HELKENGEKERVTEENKE 781 Query: 454 EYVSLVVDATLKSGIMKQVEAFRSGFSQVFDISSLQIFSPQELDYLI 594 EY++L+ + + GI +Q + F GF++V + L+ F +EL+ ++ Sbjct: 782 EYITLMTEWRMTRGIEQQTKTFLEGFNEVVPLEWLKYFDERELELIL 828
>PUB1_SCHPO (Q92462) E3 ubiquitin--protein ligase pub1 (EC 6.3.2.-)| Length = 767 Score = 63.9 bits (154), Expect = 3e-10 Identities = 49/167 (29%), Positives = 76/167 (45%) Frame = +1 Query: 94 VEYFRLVGRVVAKVLQDGRLLDLPLSTAFYKLILGQELDLFDIISFDAELGKTLQELQVL 273 + YF+ +GRV+ + R +D +FYK+IL +++ L D+ S DAE ++L + Sbjct: 500 LNYFKFIGRVIGLAIFHRRFVDAFFVVSFYKMILQKKVTLQDMESMDAEYYRSLVWI--- 556 Query: 274 VERKRFFESSCGKDQLKVADLRFRGAPIEDLCLDFTLPGFPDYVLKEGEQNTIVNIHNLE 453 D V DL F +ED C + LK +N V N Sbjct: 557 ----------LDNDITGVLDLTF---SVEDNCFGEVV----TIDLKPNGRNIEVTEENKR 599 Query: 454 EYVSLVVDATLKSGIMKQVEAFRSGFSQVFDISSLQIFSPQELDYLI 594 EYV LV ++ I +Q AF GFS++ + +F +EL+ LI Sbjct: 600 EYVDLVTVWRIQKRIEEQFNAFHEGFSELIPQELINVFDERELELLI 646
>PTR1_SCHPO (O13834) E3 ubiquitin protein ligase ptr1 (EC 6.3.2.-) (Poly(A)+ RNA| transport protein 1) Length = 3227 Score = 62.4 bits (150), Expect = 1e-09 Identities = 50/180 (27%), Positives = 79/180 (43%), Gaps = 13/180 (7%) Frame = +1 Query: 94 VEYFRLVGRVVAKVLQDGRLLDLPLSTAFYKLILGQELDLFDIISFDAELGKTLQEL--- 264 + +F+ GR++ K L DGRLLD S A YK +L + + + DI S D + K+L + Sbjct: 2958 LSFFKFTGRIIGKALYDGRLLDCHFSRAVYKHMLHRSVSVKDIESLDPDYYKSLVWMLNN 3017 Query: 265 --------QVLVERKRFFESSCGKDQLKVADL--RFRGAPIEDLCLDFTLPGFPDYVLKE 414 + VE+ F E + V DL R P+ +L Sbjct: 3018 DITDIITEEFAVEKDVFGEKT-------VVDLIPNGRNIPVTEL---------------- 3054 Query: 415 GEQNTIVNIHNLEEYVSLVVDATLKSGIMKQVEAFRSGFSQVFDISSLQIFSPQELDYLI 594 N + YV+ +VD L+ + Q+++ GFS + +QIF+ QEL+ LI Sbjct: 3055 ----------NKQNYVNRMVDYKLRESVKDQLKSLLDGFSDIIPSHLIQIFNEQELELLI 3104
>NEDD4_HUMAN (P46934) E3 ubiquitin-protein ligase NEDD4 (EC 6.3.2.-)| Length = 1000 Score = 62.0 bits (149), Expect = 1e-09 Identities = 47/168 (27%), Positives = 78/168 (46%), Gaps = 1/168 (0%) Frame = +1 Query: 94 VEYFRLVGRVVAKVLQDGRLLDLPLSTAFYKLILGQELDLFDIISFDAELGKTLQELQVL 273 + YF+ +GRV + G+LLD FYK++L + + L D+ S D+E +L+ + Sbjct: 732 LSYFKFIGRVAGMAVYHGKLLDGFFIRPFYKMMLHKPITLHDMESVDSEYYNSLRWIL-- 789 Query: 274 VERKRFFESSCGKDQLKVADLRFRGAPIEDLCLDFTLPGFP-DYVLKEGEQNTIVNIHNL 450 ++ DLRF +D L G + LK G +V N Sbjct: 790 ------------ENDPTELDLRF--------IIDEELFGQTHQHELKNGGSEIVVTNKNK 829 Query: 451 EEYVSLVVDATLKSGIMKQVEAFRSGFSQVFDISSLQIFSPQELDYLI 594 +EY+ LV+ + I KQ+ AF+ GF ++ ++IF EL+ L+ Sbjct: 830 KEYIYLVIQWRFVNRIQKQMAAFKEGFFELIPQDLIKIFDENELELLM 877
>NED4L_MOUSE (Q8CFI0) E3 ubiquitin-protein ligase NEDD4-like protein (EC 6.3.2.-)| (Nedd4-2) (NEDD4.2) Length = 1004 Score = 61.6 bits (148), Expect = 2e-09 Identities = 47/168 (27%), Positives = 77/168 (45%), Gaps = 1/168 (0%) Frame = +1 Query: 94 VEYFRLVGRVVAKVLQDGRLLDLPLSTAFYKLILGQELDLFDIISFDAELGKTLQELQVL 273 + YF +GRV + G+LLD FYK++LG+++ L D+ S D+E +L+ + Sbjct: 736 LSYFTFIGRVAGLAVFHGKLLDGFFIRPFYKMMLGKQITLNDMESVDSEYYNSLKWIL-- 793 Query: 274 VERKRFFESSCGKDQLKVADLRFRGAPIEDLCLDFTLPGFPDYV-LKEGEQNTIVNIHNL 450 ++ DL F C+D G V LK +V N Sbjct: 794 ------------ENDPTELDLMF--------CIDEENFGQTYQVDLKPNGSEIMVTNENK 833 Query: 451 EEYVSLVVDATLKSGIMKQVEAFRSGFSQVFDISSLQIFSPQELDYLI 594 EY+ LV+ + + KQ+ AF GF+++ I ++IF EL+ L+ Sbjct: 834 REYIDLVIQWRFVNRVQKQMNAFLEGFTELLPIDLIKIFDENELELLM 881
>NED4L_HUMAN (Q96PU5) E3 ubiquitin-protein ligase NEDD4-like protein (EC 6.3.2.-)| (Nedd4-2) (NEDD4.2) Length = 975 Score = 61.6 bits (148), Expect = 2e-09 Identities = 47/168 (27%), Positives = 77/168 (45%), Gaps = 1/168 (0%) Frame = +1 Query: 94 VEYFRLVGRVVAKVLQDGRLLDLPLSTAFYKLILGQELDLFDIISFDAELGKTLQELQVL 273 + YF +GRV + G+LLD FYK++LG+++ L D+ S D+E +L+ + Sbjct: 707 LSYFTFIGRVAGLAVFHGKLLDGFFIRPFYKMMLGKQITLNDMESVDSEYYNSLKWIL-- 764 Query: 274 VERKRFFESSCGKDQLKVADLRFRGAPIEDLCLDFTLPGFPDYV-LKEGEQNTIVNIHNL 450 ++ DL F C+D G V LK +V N Sbjct: 765 ------------ENDPTELDLMF--------CIDEENFGQTYQVDLKPNGSEIMVTNENK 804 Query: 451 EEYVSLVVDATLKSGIMKQVEAFRSGFSQVFDISSLQIFSPQELDYLI 594 EY+ LV+ + + KQ+ AF GF+++ I ++IF EL+ L+ Sbjct: 805 REYIDLVIQWRFVNRVQKQMNAFLEGFTELLPIDLIKIFDENELELLM 852
>NEDD4_RAT (Q62940) E3 ubiquitin-protein ligase NEDD4 (EC 6.3.2.-)| Length = 887 Score = 61.2 bits (147), Expect = 2e-09 Identities = 47/168 (27%), Positives = 78/168 (46%), Gaps = 1/168 (0%) Frame = +1 Query: 94 VEYFRLVGRVVAKVLQDGRLLDLPLSTAFYKLILGQELDLFDIISFDAELGKTLQELQVL 273 + YF+ +GRV + G+LLD FYK++L + + L D+ S D+E +L+ + Sbjct: 619 LSYFKFIGRVAGMAVYHGKLLDGFFIRPFYKMMLQKLITLHDMESVDSEYYSSLRWIL-- 676 Query: 274 VERKRFFESSCGKDQLKVADLRFRGAPIEDLCLDFTLPGFP-DYVLKEGEQNTIVNIHNL 450 ++ DLRF +D L G + LK G +V N Sbjct: 677 ------------ENDPTELDLRF--------IIDEELFGQTHQHELKTGGSEVVVTNKNK 716 Query: 451 EEYVSLVVDATLKSGIMKQVEAFRSGFSQVFDISSLQIFSPQELDYLI 594 +EY+ LV+ + I KQ+ AF+ GF ++ ++IF EL+ L+ Sbjct: 717 KEYIYLVIQWRFVNRIQKQMAAFKEGFFELIPQDLIKIFDENELELLM 764
>NEDD4_MOUSE (P46935) E3 ubiquitin-protein ligase NEDD4 (EC 6.3.2.-) (Neural| precursor cell expressed developmentally down-regulated protein 4) Length = 887 Score = 60.8 bits (146), Expect = 3e-09 Identities = 47/168 (27%), Positives = 78/168 (46%), Gaps = 1/168 (0%) Frame = +1 Query: 94 VEYFRLVGRVVAKVLQDGRLLDLPLSTAFYKLILGQELDLFDIISFDAELGKTLQELQVL 273 + YF+ +GRV + G+LLD FYK++L + + L D+ S D+E +L+ + Sbjct: 619 LSYFKFIGRVAGMAVYHGKLLDGFFIRPFYKMMLQKLITLHDMESVDSEYYSSLRWIL-- 676 Query: 274 VERKRFFESSCGKDQLKVADLRFRGAPIEDLCLDFTLPGFP-DYVLKEGEQNTIVNIHNL 450 ++ DLRF +D L G + LK G +V N Sbjct: 677 ------------ENDPTELDLRF--------IIDEELFGQTHQHELKTGGSEIVVTNKNK 716 Query: 451 EEYVSLVVDATLKSGIMKQVEAFRSGFSQVFDISSLQIFSPQELDYLI 594 +EY+ LV+ + I KQ+ AF+ GF ++ ++IF EL+ L+ Sbjct: 717 KEYIYLVIQWRFVNRIQKQMAAFKEGFFELIPQDLIKIFDENELELLM 764
>HECD1_HUMAN (Q9ULT8) E3 ubiquitin-protein ligase HECTD1 (HECT domain-containing| protein 1) (E3 ligase for inhibin receptor) (EULIR) Length = 2612 Score = 60.8 bits (146), Expect = 3e-09 Identities = 33/86 (38%), Positives = 51/86 (59%), Gaps = 6/86 (6%) Frame = +1 Query: 355 IEDLCLDFT------LPGFPDYVLKEGEQNTIVNIHNLEEYVSLVVDATLKSGIMKQVEA 516 IEDL L+F + GF LK ++ ++ + N EEYV L+ D + +GI KQ+EA Sbjct: 2407 IEDLGLNFQFCPSSRIYGFTAVDLKPSGEDEMITMDNAEEYVDLMFDFCMHTGIQKQMEA 2466 Query: 517 FRSGFSQVFDISSLQIFSPQELDYLI 594 FR GF++VF + L FS +E+ ++ Sbjct: 2467 FRDGFNKVFPMEKLSSFSHEEVQMIL 2492 Score = 51.2 bits (121), Expect = 2e-06 Identities = 25/64 (39%), Positives = 38/64 (59%) Frame = +1 Query: 1 PGNLIQAPLGLFPRPWPSNVDTSEGSRFLKVVEYFRLVGRVVAKVLQDGRLLDLPLSTAF 180 PG +Q GLF P+P + D E ++ + F +G +AK +QD RL+DLP+S F Sbjct: 2218 PGYYVQRSCGLFTAPFPQDSDELE-----RITKLFHFLGIFLAKCIQDNRLVDLPISKPF 2272 Query: 181 YKLI 192 +KL+ Sbjct: 2273 FKLM 2276
>NED4L_PONPY (Q5RBF2) E3 ubiquitin-protein ligase NEDD4-like protein (EC 6.3.2.-)| Length = 959 Score = 60.1 bits (144), Expect = 5e-09 Identities = 46/168 (27%), Positives = 77/168 (45%), Gaps = 1/168 (0%) Frame = +1 Query: 94 VEYFRLVGRVVAKVLQDGRLLDLPLSTAFYKLILGQELDLFDIISFDAELGKTLQELQVL 273 + YF +GRV + G+LLD FYK++LG+++ L D+ S D+E +L+ + Sbjct: 691 LSYFTFIGRVAGLAVFHGKLLDGFFIRPFYKMMLGKQITLNDMESVDSEYYNSLKWIL-- 748 Query: 274 VERKRFFESSCGKDQLKVADLRFRGAPIEDLCLDFTLPGFPDYV-LKEGEQNTIVNIHNL 450 ++ DL F C+D G V L+ +V N Sbjct: 749 ------------ENDPTELDLMF--------CIDEENFGQTYQVDLEPNGSEIMVTNENK 788 Query: 451 EEYVSLVVDATLKSGIMKQVEAFRSGFSQVFDISSLQIFSPQELDYLI 594 EY+ LV+ + + KQ+ AF GF+++ I ++IF EL+ L+ Sbjct: 789 REYIDLVIQWRFVNRVQKQMNAFLEGFTELLPIDLIKIFDENELELLM 836
>SMUF1_HUMAN (Q9HCE7) Smad ubiquitination regulatory factor 1 (EC 6.3.2.-)| (Ubiquitin--protein ligase SMURF1) (Smad-specific E3 ubiquitin ligase 1) (hSMURF1) Length = 757 Score = 55.1 bits (131), Expect = 2e-07 Identities = 46/168 (27%), Positives = 73/168 (43%), Gaps = 1/168 (0%) Frame = +1 Query: 94 VEYFRLVGRVVAKVLQDGRLLDLPLSTAFYKLILGQELDLFDIISFDAELGKTLQELQVL 273 + YF VGR++ + G ++ + FYK +LG+ + L D+ S D EL K+L + Sbjct: 486 LSYFHFVGRIMGLAVFHGHYINGGFTVPFYKQLLGKPIQLSDLESVDPELHKSLVWI--- 542 Query: 274 VERKRFFESSCGKDQLKVADLRFRGAPIEDLCLDFTLPG-FPDYVLKEGEQNTIVNIHNL 450 D V D F C++ G + LK +N V N Sbjct: 543 ----------LENDITPVLDHTF--------CVEHNAFGRILQHELKPNGRNVPVTEENK 584 Query: 451 EEYVSLVVDATLKSGIMKQVEAFRSGFSQVFDISSLQIFSPQELDYLI 594 +EYV L V+ GI Q A + GF+++ L+ F +EL+ +I Sbjct: 585 KEYVRLYVNWRFMRGIEAQFLALQKGFNELIPQHLLKPFDQKELELII 632
>SMUF1_XENLA (Q9PUN2) Smad ubiquitination regulatory factor 1 (EC 6.3.2.-)| (Ubiquitin--protein ligase SMURF1) (Smad-specific E3 ubiquitin ligase) (xSMURF1) Length = 731 Score = 55.1 bits (131), Expect = 2e-07 Identities = 46/168 (27%), Positives = 73/168 (43%), Gaps = 1/168 (0%) Frame = +1 Query: 94 VEYFRLVGRVVAKVLQDGRLLDLPLSTAFYKLILGQELDLFDIISFDAELGKTLQELQVL 273 + YF VGR++ + G ++ + FYK +LG+ + L D+ S D EL K+L + Sbjct: 460 LSYFHFVGRIMGLAVFHGHYINGGFTVPFYKQLLGKPIQLSDLESVDPELHKSLVWI--- 516 Query: 274 VERKRFFESSCGKDQLKVADLRFRGAPIEDLCLDFTLPG-FPDYVLKEGEQNTIVNIHNL 450 D V D F C++ G + LK +N V N Sbjct: 517 ----------LENDITSVLDHTF--------CVEHNAFGRLLQHELKPNGKNLQVTEENK 558 Query: 451 EEYVSLVVDATLKSGIMKQVEAFRSGFSQVFDISSLQIFSPQELDYLI 594 +EYV L V+ GI Q A + GF+++ L+ F +EL+ +I Sbjct: 559 KEYVRLYVNWRFMRGIEAQFLALQKGFNELIPQHLLKPFEQKELELII 606
>SMUF1_MOUSE (Q9CUN6) Smad ubiquitination regulatory factor 1 (EC 6.3.2.-)| (Ubiquitin--protein ligase SMURF1) (Smad-specific E3 ubiquitin ligase 1) Length = 731 Score = 55.1 bits (131), Expect = 2e-07 Identities = 46/168 (27%), Positives = 73/168 (43%), Gaps = 1/168 (0%) Frame = +1 Query: 94 VEYFRLVGRVVAKVLQDGRLLDLPLSTAFYKLILGQELDLFDIISFDAELGKTLQELQVL 273 + YF VGR++ + G ++ + FYK +LG+ + L D+ S D EL K+L + Sbjct: 460 LSYFHFVGRIMGLAVFHGHYINGGFTVPFYKQLLGKPIQLSDLESVDPELHKSLVWI--- 516 Query: 274 VERKRFFESSCGKDQLKVADLRFRGAPIEDLCLDFTLPG-FPDYVLKEGEQNTIVNIHNL 450 D V D F C++ G + LK +N V N Sbjct: 517 ----------LENDITPVLDHTF--------CVEHNAFGRILQHELKPNGRNVPVTEENK 558 Query: 451 EEYVSLVVDATLKSGIMKQVEAFRSGFSQVFDISSLQIFSPQELDYLI 594 +EYV L V+ GI Q A + GF+++ L+ F +EL+ +I Sbjct: 559 KEYVRLYVNWRFMRGIEAQFLALQKGFNELIPQHLLKPFDQKELELII 606
>HUL4_ASHGO (Q757T0) Probable ubiquitin-protein ligase HUL4 (EC 6.3.2.-) (HECT| ubiquitin ligase 4) Length = 839 Score = 54.7 bits (130), Expect = 2e-07 Identities = 48/173 (27%), Positives = 75/173 (43%), Gaps = 7/173 (4%) Frame = +1 Query: 97 EYFRLVGRVVAKVLQDGRLLDLPLSTAFYKLILGQELDLFDIISFDAELGKTLQELQVLV 276 E + L G V+ + + +LDL AFYK I G+ L + D + E G + L++L Sbjct: 570 ELYYLFGVVLGLAIYNSTILDLKFPRAFYKKICGEVLSVNDFLELYPETGTNM--LKMLE 627 Query: 277 ERKRFFES-------SCGKDQLKVADLRFRGAPIEDLCLDFTLPGFPDYVLKEGEQNTIV 435 FE +C D+ + + +R LC D G V +E Sbjct: 628 YDGEDFEDIFALTFETCFPDRFDESKIHYR-----QLCPD----GSTQAVTRE------- 671 Query: 436 NIHNLEEYVSLVVDATLKSGIMKQVEAFRSGFSQVFDISSLQIFSPQELDYLI 594 N EY L +D L I E+FR+GF V + +S ++F +EL+ L+ Sbjct: 672 ---NKHEYFRLWMDFYLNRSIAPGFESFRNGFFHVIEGNSFRLFGSEELEQLV 721
>TOM1_ASHGO (Q756G2) Probable E3 ubiquitin protein ligase TOM1 (EC 6.3.2.-)| Length = 3258 Score = 53.5 bits (127), Expect = 4e-07 Identities = 42/172 (24%), Positives = 74/172 (43%), Gaps = 5/172 (2%) Frame = +1 Query: 94 VEYFRLVGRVVAKVLQDGRLLDLPLSTAFYKLILGQELDLFDIISFDAELGKTL-----Q 258 + +F+ +G ++ K + D LD S YK ILG+ + L D+ S D + K+L Sbjct: 2989 LSFFKFIGMIIGKAISDQCFLDCHFSREVYKNILGKPVALKDMESLDLDYYKSLIWILEN 3048 Query: 259 ELQVLVERKRFFESSCGKDQLKVADLRFRGAPIEDLCLDFTLPGFPDYVLKEGEQNTIVN 438 ++ ++E + F + + KV +L GA + V Sbjct: 3049 DITDIIE-ETFSVETDDYGEHKVIELIENGAHVA------------------------VT 3083 Query: 439 IHNLEEYVSLVVDATLKSGIMKQVEAFRSGFSQVFDISSLQIFSPQELDYLI 594 N +YV +V+ L++ + Q+E F GF + + IF QEL+ L+ Sbjct: 3084 EQNKHDYVKKIVEYKLQTSVKDQMENFLQGFYAIIPKDLISIFDEQELELLV 3135
>SMUF2_HUMAN (Q9HAU4) Smad ubiquitination regulatory factor 2 (EC 6.3.2.-)| (Ubiquitin--protein ligase SMURF2) (Smad-specific E3 ubiquitin ligase 2) (hSMURF2) Length = 748 Score = 52.8 bits (125), Expect = 8e-07 Identities = 42/168 (25%), Positives = 71/168 (42%), Gaps = 1/168 (0%) Frame = +1 Query: 94 VEYFRLVGRVVAKVLQDGRLLDLPLSTAFYKLILGQELDLFDIISFDAELGKTLQELQVL 273 + YF VGR++ + G +D + FYK +LG+ + L D+ D +L +L Sbjct: 480 LSYFHFVGRIMGMAVFHGHYIDGGFTLPFYKQLLGKSITLDDMELVDPDLHNSL------ 533 Query: 274 VERKRFFESSCGKDQLKVADLRFRGAPIEDLCLDFTLPG-FPDYVLKEGEQNTIVNIHNL 450 + + + G C++ G + LK ++ VN N Sbjct: 534 ---------------VWILENDITGVLDHTFCVEHNAYGEIIQHELKPNGKSIPVNEENK 578 Query: 451 EEYVSLVVDATLKSGIMKQVEAFRSGFSQVFDISSLQIFSPQELDYLI 594 +EYV L V+ GI Q A + GF++V L+ F +EL+ +I Sbjct: 579 KEYVRLYVNWRFLRGIEAQFLALQKGFNEVIPQHLLKTFDEKELELII 626
>PUB3_SCHPO (O14326) E3 ubiquitin--protein ligase pub3 (EC 6.3.2.-)| Length = 786 Score = 52.8 bits (125), Expect = 8e-07 Identities = 45/178 (25%), Positives = 74/178 (41%), Gaps = 11/178 (6%) Frame = +1 Query: 94 VEYFRLVGRVVAKVLQDGRLLDLPLSTAFYKLILGQELDLFDIISFDAELGKTLQ----- 258 + YFR +GRV+ + R LD + YK +L +++ L D+ S DAE ++L+ Sbjct: 519 LNYFRFIGRVIGLAIFHRRFLDAFFVVSLYKKLLRKKVSLADMESIDAEFYRSLKWVLEN 578 Query: 259 ------ELQVLVERKRFFESSCGKDQLKVADLRFRGAPIEDLCLDFTLPGFPDYVLKEGE 420 +L VE F E ++ +L G IE Sbjct: 579 DITGILDLTFSVEEDHFGE-------VRTVELITNGENIE-------------------- 611 Query: 421 QNTIVNIHNLEEYVSLVVDATLKSGIMKQVEAFRSGFSQVFDISSLQIFSPQELDYLI 594 V N ++YV LV + + + +Q AF SGF ++ + +F +EL+ LI Sbjct: 612 ----VTEENKKKYVDLVTEWRVSKRVEQQFNAFYSGFVELVSPDLVNVFDERELELLI 665
>PUB2_SCHPO (Q9UTG2) E3 ubiquitin--protein ligase pub2 (EC 6.3.2.-)| Length = 671 Score = 52.4 bits (124), Expect = 1e-06 Identities = 47/165 (28%), Positives = 72/165 (43%) Frame = +1 Query: 100 YFRLVGRVVAKVLQDGRLLDLPLSTAFYKLILGQELDLFDIISFDAELGKTLQELQVLVE 279 YFR VGRV+ + R LD+ FYK IL + L L D+ D ++L+ ++ Sbjct: 406 YFRFVGRVMGLAIYHRRYLDVQFVLPFYKRILQKPLCLEDVKDVDEVYYESLK----WIK 461 Query: 280 RKRFFESSCGKDQLKVADLRFRGAPIEDLCLDFTLPGFPDYVLKEGEQNTIVNIHNLEEY 459 ES C V + RF E + +D G +N VN N Y Sbjct: 462 NNDVDESLC--LNFSVEENRFG----ESVTVDLIPNG----------RNIAVNNQNKMNY 505 Query: 460 VSLVVDATLKSGIMKQVEAFRSGFSQVFDISSLQIFSPQELDYLI 594 + + + L + +Q A + G +++ S LQIF+ ELD L+ Sbjct: 506 LKALTEHKLVTSTEEQFNALKGGLNELIPDSVLQIFNENELDTLL 550
>UBE3C_HUMAN (Q15386) Ubiquitin-protein ligase E3C (EC 6.3.2.-)| Length = 1083 Score = 51.6 bits (122), Expect = 2e-06 Identities = 48/172 (27%), Positives = 76/172 (44%), Gaps = 7/172 (4%) Frame = +1 Query: 100 YFRLVGRVVAKVLQDGRLLDLPLSTAFYKLILGQ--ELDLFDIISFDAELGKTLQELQVL 273 ++ +GR++ K L + L++LP + F +LG ++D+ + S D E+ K L Sbjct: 817 HYYFLGRMLGKALYENMLVELPFAGFFLSKLLGTSADVDIHHLASLDPEVYKNL------ 870 Query: 274 VERKRFFESSCGKDQLKVADLRFRGAPIEDLCLDFTLP----GFPDYV-LKEGEQNTIVN 438 F S D +E+L L+FT+ G V LK G ++ V Sbjct: 871 -----LFLKSYEDD-------------VEELGLNFTVVNNDLGEAQVVELKFGGKDIPVT 912 Query: 439 IHNLEEYVSLVVDATLKSGIMKQVEAFRSGFSQVFDISSLQIFSPQELDYLI 594 N Y+ LV D L I + AFR G + V + L++F QE+ LI Sbjct: 913 SANRIAYIHLVADYRLNRQIRQHCLAFRQGLANVVSLEWLRMFDQQEIQVLI 964
>UBE3C_MOUSE (Q80U95) Ubiquitin-protein ligase E3C (EC 6.3.2.-)| Length = 1083 Score = 50.4 bits (119), Expect = 4e-06 Identities = 48/172 (27%), Positives = 75/172 (43%), Gaps = 7/172 (4%) Frame = +1 Query: 100 YFRLVGRVVAKVLQDGRLLDLPLSTAFYKLILGQ--ELDLFDIISFDAELGKTLQELQVL 273 ++ +GR++ K L + L++LP + F +LG ++D+ + S D E Sbjct: 817 HYYFLGRMLGKALYENMLVELPFAGFFLSKLLGTSADVDIHHLASLDPE----------- 865 Query: 274 VERKRFFESSCGKDQLKVADLRFRGAPIEDLCLDFTLP----GFPDYV-LKEGEQNTIVN 438 V R F S +D +E+L L+FT+ G V LK G ++ V Sbjct: 866 VYRNLLFLKSYEED-------------VEELGLNFTVVNNDLGEAQVVELKFGGKDIPVT 912 Query: 439 IHNLEEYVSLVVDATLKSGIMKQVEAFRSGFSQVFDISSLQIFSPQELDYLI 594 N Y+ LV D L I AFR G + V + L++F QE+ LI Sbjct: 913 GANRIAYIHLVADYRLNKQIRPHCLAFRQGLANVVSLEWLRMFDQQEIQVLI 964
>UBE3A_HUMAN (Q05086) Ubiquitin-protein ligase E3A (EC 6.3.2.-) (E6AP| ubiquitin-protein ligase) (Oncogenic protein-associated protein E6-AP) (Human papillomavirus E6-associated protein) (NY-REN-54 antigen) Length = 875 Score = 49.7 bits (117), Expect = 6e-06 Identities = 43/171 (25%), Positives = 76/171 (44%), Gaps = 7/171 (4%) Frame = +1 Query: 103 FRLVGRVVAKVLQDGRLLDLPLSTAFYKLILGQELDLFDIISFDAELGKTLQELQVLVER 282 F L+G V+ + + +LD+ Y+ ++G++ D+ L ++L++L Sbjct: 612 FTLIGIVLGLAIYNNCILDVHFPMVVYRKLMGKKGTFRDLGDSHPVLYQSLKDL------ 665 Query: 283 KRFFESSCGKDQLKVADLRFRGAPIEDLCLDFTLP-----GFPD-YVLKEGEQNTIVNIH 444 L + G +D+ + F + G P Y LKE + Sbjct: 666 -----------------LEYEGNVEDDMMITFQISQTDLFGNPMMYDLKENGDKIPITNE 708 Query: 445 NLEEYVSLVVDATLKSGIMKQVEAFRSGFSQVFDISSLQ-IFSPQELDYLI 594 N +E+V+L D L + KQ +AFR GF V + S L+ +F P+E++ LI Sbjct: 709 NRKEFVNLYSDYILNKSVEKQFKAFRRGFHMVTNESPLKYLFRPEEIELLI 759
>SMUF1_DROME (Q9V853) E3 ubiquitin-protein ligase Smurf1 (EC 6.3.2.-) (Smad| ubiquitination regulatory factor 1 homolog) (DSmurf) (Lethal with a checkpoint kinase protein) Length = 1061 Score = 49.3 bits (116), Expect = 8e-06 Identities = 44/170 (25%), Positives = 70/170 (41%), Gaps = 3/170 (1%) Frame = +1 Query: 94 VEYFRLVGRVVAKVLQDGRLLDLPLSTAFYKLILGQELDLFDIISFDAELGKTLQELQVL 273 + YF VGR + + G LD +T FYK +L + + L DI D +L ++L + Sbjct: 789 LSYFHFVGRTLGIAVFHGHCLDGGFTTPFYKQLLNKPITLGDIEGVDPDLHRSLTWM--- 845 Query: 274 VERKRFFESSCG---KDQLKVADLRFRGAPIEDLCLDFTLPGFPDYVLKEGEQNTIVNIH 444 ES+ + V + F + + LK G + V Sbjct: 846 ------LESNISGIIESTFSVENNSFGALVVHE--------------LKPGGASIPVTEE 885 Query: 445 NLEEYVSLVVDATLKSGIMKQVEAFRSGFSQVFDISSLQIFSPQELDYLI 594 N EYV L V+ GI +Q A + GF ++ L+ F +EL+ +I Sbjct: 886 NKREYVKLYVNYRFMRGIEQQFLALQKGFCELIPSHLLRPFDERELELVI 935
>HERC3_HUMAN (Q15034) HECT domain and RCC1-like domain protein 3| Length = 1050 Score = 48.5 bits (114), Expect = 1e-05 Identities = 42/167 (25%), Positives = 70/167 (41%), Gaps = 6/167 (3%) Frame = +1 Query: 100 YFRLVGRVVAKVLQDGRLLDLPLSTAFYKLILGQELDLFDIISFDAELGKTLQELQVLVE 279 +F L+G + + ++DL A YK +L + L D+ G++LQEL Sbjct: 787 WFHLIGITCGLAIYNSTVVDLHFPLALYKKLLNVKPGLEDLKELSPTEGRSLQEL----- 841 Query: 280 RKRFFESSCGKDQLKVADLRFRGAPIED-LCLDFTLPGFPDYVLKE-----GEQNTIVNI 441 L + G +E+ CL+FT+ V+++ G N V Sbjct: 842 ------------------LDYPGEDVEETFCLNFTICRESYGVIEQKKLIPGGDNVTVCK 883 Query: 442 HNLEEYVSLVVDATLKSGIMKQVEAFRSGFSQVFDISSLQIFSPQEL 582 N +E+V V+ + + + AF SGF +V L++F P EL Sbjct: 884 DNRQEFVDAYVNYVFQISVHEWYTAFSSGFLKVCGGKVLELFQPSEL 930
>RSP5_YEAST (P39940) E3 ubiquitin--protein ligase RSP5 (EC 6.3.2.-)| Length = 809 Score = 48.5 bits (114), Expect = 1e-05 Identities = 45/167 (26%), Positives = 72/167 (43%) Frame = +1 Query: 94 VEYFRLVGRVVAKVLQDGRLLDLPLSTAFYKLILGQELDLFDIISFDAELGKTLQELQVL 273 + YF+ +GRVV + R LD A YK++L +++ L D+ DAE+ +L + Sbjct: 542 LNYFKFIGRVVGLGVFHRRFLDAFFVGALYKMMLRKKVVLQDMEGVDAEVYNSLNWM--- 598 Query: 274 VERKRFFESSCGKDQLKVADLRFRGAPIEDLCLDFTLPGFPDYVLKEGEQNTIVNIHNLE 453 E+S V DL F D LK +N V N + Sbjct: 599 ------LENSID----GVLDLTFSAD-------DERFGEVVTVDLKPDGRNIEVTDGNKK 641 Query: 454 EYVSLVVDATLKSGIMKQVEAFRSGFSQVFDISSLQIFSPQELDYLI 594 EYV L + + +Q +AF GF+++ + +F +EL+ LI Sbjct: 642 EYVELYTQWRIVDRVQEQFKAFMDGFNELIPEDLVTVFDERELELLI 688
>HUL4_YEAST (P40985) Probable ubiquitin-protein ligase HUL4 (EC 6.3.2.-) (HECT| ubiquitin ligase 4) Length = 892 Score = 46.6 bits (109), Expect = 5e-05 Identities = 48/186 (25%), Positives = 80/186 (43%), Gaps = 4/186 (2%) Frame = +1 Query: 49 PSNVDTSEGSRFLKVVEYFRLVGRVVAKVLQDGRLLDLPLSTAFYKLILGQELDLFDIIS 228 P N D S+G +E + L G V+ + + +LDL A YK + + L D Sbjct: 599 PPNFDKSKGKN--SQLELYYLFGVVMGLAIFNSTILDLQFPKALYKKLCSEPLSFEDYSE 656 Query: 229 FDAELGKTLQELQVLVERKRFFESSCGKDQLKVADLRFRGAPIEDLCLDFTLPGFPDYV- 405 E + L +++L + FE V L F + + +YV Sbjct: 657 LFPETSRNL--IKMLNYTEDNFED--------VFSLTFETTYRNNNWILNDSKSSKEYVT 706 Query: 406 --LKEGEQNTIVNIHNLEEYVSLVVDATLKSGIMKQVEAFRSGFSQVF-DISSLQIFSPQ 576 L E +N + N E+V V+ L+ I Q F SGF +VF + +S+++F+ + Sbjct: 707 VELCENGRNVPITQSNKHEFVMKWVEFYLEKSIEPQYNKFVSGFKRVFAECNSIKLFNSE 766 Query: 577 ELDYLI 594 EL+ L+ Sbjct: 767 ELERLV 772
>HERC2_HUMAN (O95714) HECT domain and RCC1-like domain-containing protein 2| Length = 4834 Score = 45.4 bits (106), Expect = 1e-04 Identities = 36/164 (21%), Positives = 68/164 (41%) Frame = +1 Query: 103 FRLVGRVVAKVLQDGRLLDLPLSTAFYKLILGQELDLFDIISFDAELGKTLQELQVLVER 282 FR +G ++ ++ G L L L+ +K + G L + D+ D + L Sbjct: 4533 FRFLGVLLGIAIRTGSPLSLNLAEPVWKQLAGMSLTIADLSEVDKDFIPGL--------- 4583 Query: 283 KRFFESSCGKDQLKVADLRFRGAPIEDLCLDFTLPGFPDYVLKEGEQNTIVNIHNLEEYV 462 + + D E + L FT+P ++ ++T + + N EYV Sbjct: 4584 ------------MYIRDNEATSEEFEAMSLPFTVPSASGQDIQLSSKHTHITLDNRAEYV 4631 Query: 463 SLVVDATLKSGIMKQVEAFRSGFSQVFDISSLQIFSPQELDYLI 594 L ++ L +QV A R G ++V + L +F+ EL+ ++ Sbjct: 4632 RLAINYRLHE-FDEQVAAVREGMARVVPVPLLSLFTGYELETMV 4674
>HERC2_MOUSE (Q4U2R1) HECT domain and RCC1-like domain-containing protein 2| Length = 4836 Score = 45.4 bits (106), Expect = 1e-04 Identities = 36/164 (21%), Positives = 68/164 (41%) Frame = +1 Query: 103 FRLVGRVVAKVLQDGRLLDLPLSTAFYKLILGQELDLFDIISFDAELGKTLQELQVLVER 282 FR +G ++ ++ G L L L+ +K + G L + D+ D + L Sbjct: 4535 FRFLGVLLGIAIRTGSPLSLNLAEPVWKQLAGMSLTIADLSEVDKDFIPGL--------- 4585 Query: 283 KRFFESSCGKDQLKVADLRFRGAPIEDLCLDFTLPGFPDYVLKEGEQNTIVNIHNLEEYV 462 + + D E + L FT+P ++ ++T + + N EYV Sbjct: 4586 ------------MYIRDNEATSEEFEAMSLPFTVPSASGQDIQLSSKHTHITLDNRAEYV 4633 Query: 463 SLVVDATLKSGIMKQVEAFRSGFSQVFDISSLQIFSPQELDYLI 594 L ++ L +QV A R G ++V + L +F+ EL+ ++ Sbjct: 4634 RLAINYRLHE-FDEQVAAVREGMARVVPVPLLSLFTGYELETMV 4676
>UBE3A_MOUSE (O08759) Ubiquitin-protein ligase E3A (EC 6.3.2.-) (Oncogenic| protein-associated protein E6-AP) Length = 885 Score = 43.5 bits (101), Expect = 5e-04 Identities = 41/171 (23%), Positives = 75/171 (43%), Gaps = 7/171 (4%) Frame = +1 Query: 103 FRLVGRVVAKVLQDGRLLDLPLSTAFYKLILGQELDLFDIISFDAELGKTLQELQVLVER 282 F L+G ++ + + +LD+ Y+ ++G++ D+ L ++L++L Sbjct: 623 FTLIG-ILGLAIYNNCILDVHFPMVVYRKLMGKKGTFRDLGDSHPVLYQSLKDL------ 675 Query: 283 KRFFESSCGKDQLKVADLRFRGAPIEDLCLDFTLP-----GFPD-YVLKEGEQNTIVNIH 444 L + G+ +D+ + F + G P Y LKE + Sbjct: 676 -----------------LEYEGSVEDDMMITFQISQTDLFGNPMMYDLKENGDKIPITNE 718 Query: 445 NLEEYVSLVVDATLKSGIMKQVEAFRSGFSQVFDISSLQ-IFSPQELDYLI 594 N +E+V D L + KQ +AFR GF V + S L+ +F P+E++ LI Sbjct: 719 NRKEFVISYSDYILNKSVEKQFKAFRRGFHMVTNESPLKYLFRPEEIELLI 769
>HYD_DROME (P51592) Ubiquitin--protein ligase hyd (EC 6.3.2.-) (Protein| hyperplastic discs) Length = 2885 Score = 42.7 bits (99), Expect = 8e-04 Identities = 41/175 (23%), Positives = 76/175 (43%) Frame = +1 Query: 70 EGSRFLKVVEYFRLVGRVVAKVLQDGRLLDLPLSTAFYKLILGQELDLFDIISFDAELGK 249 +G + + FR +GR++ L LL L L K ILG+++ D+ FD L + Sbjct: 2604 QGFASFERINAFRNIGRLIGLCLLQNELLPLFLQRHVLKYILGRKIKFHDLAFFDPALYE 2663 Query: 250 TLQELQVLVERKRFFESSCGKDQLKVADLRFRGAPIEDLCLDFTLPGFPDYVLKEGEQNT 429 + +++ + K G++ + +L F + DL + G + L G ++ Sbjct: 2664 SFRQIIQNAQTKE------GEETINRMELCF----VIDLMKE---EGCGNRELIPGGRDV 2710 Query: 430 IVNIHNLEEYVSLVVDATLKSGIMKQVEAFRSGFSQVFDISSLQIFSPQELDYLI 594 V N+ EYV + L K +EA + G V +S+ + ++L L+ Sbjct: 2711 AVTSSNIFEYVRRYTEYRLIKSQEKALEALKDGVFDVLPDNSMINLTAEDLRLLL 2765
>HUL5_YEAST (P53119) Probable ubiquitin-protein ligase HUL5 (EC 6.3.2.-)| Length = 910 Score = 42.4 bits (98), Expect = 0.001 Identities = 46/173 (26%), Positives = 71/173 (41%), Gaps = 6/173 (3%) Frame = +1 Query: 94 VEYFRLVGRVVAKVLQDGRLLDLPLSTAFYKLIL----GQELDLFDIISFDAELGKTLQE 261 ++Y +G+VV K L + L+D+ + F K +L G D+ S+D+ L L + Sbjct: 641 LKYIWFLGKVVGKCLYEHVLIDVSFADFFLKKLLNYSNGFLSSFSDLGSYDSVLYNNLIK 700 Query: 262 LQVLVERKRFFESSCGKDQLKVADLRFRGAPIEDLC--LDFTLPGFPDYVLKEGEQNTIV 435 L + D++K DL F E +D G YV K+ Sbjct: 701 LLNMT-----------TDEIKSLDLTFEIDEPESSAKVVDLIPNGSKTYVTKD------- 742 Query: 436 NIHNLEEYVSLVVDATLKSGIMKQVEAFRSGFSQVFDISSLQIFSPQELDYLI 594 N+ YV+ V D L K V AF G S + +++F+ EL LI Sbjct: 743 ---NVLLYVTKVTDYKLNKRCFKPVSAFHGGLSVIIAPHWMEMFNSIELQMLI 792
>EDD1_RAT (Q62671) Ubiquitin-protein ligase EDD1 (EC 6.3.2.-) (Hyperplastic| discs protein homolog) (100 kDa protein) (Fragment) Length = 920 Score = 38.1 bits (87), Expect = 0.019 Identities = 39/164 (23%), Positives = 69/164 (42%) Frame = +1 Query: 103 FRLVGRVVAKVLQDGRLLDLPLSTAFYKLILGQELDLFDIISFDAELGKTLQELQVLVER 282 FR +GR++ L L + L+ K++LG++++ D FD + ++L++L +L Sbjct: 650 FRNIGRILGLCLLQNELCPITLNRHVIKVLLGRKVNWHDFAFFDPVMYESLRQL-ILAS- 707 Query: 283 KRFFESSCGKDQLKVADLRFRGAPIEDLCLDFTLPGFPDYVLKEGEQNTIVNIHNLEEYV 462 +SS DL F DLC + G L N V N+ EYV Sbjct: 708 ----QSSDADAVFSAMDLAF----AVDLCKE---EGGGQVELIPNGVNIPVTPQNVYEYV 756 Query: 463 SLVVDATLKSGIMKQVEAFRSGFSQVFDISSLQIFSPQELDYLI 594 + + + + A R G V +SL+ + ++ L+ Sbjct: 757 RKYAEHRMLVVAEQPLHAMRKGLLDVLPKNSLEDLTAEDFRLLV 800
>EDD1_MOUSE (Q80TP3) Ubiquitin-protein ligase EDD1 (EC 6.3.2.-) (Hyperplastic| discs protein homolog) Length = 2792 Score = 37.7 bits (86), Expect = 0.025 Identities = 39/164 (23%), Positives = 69/164 (42%) Frame = +1 Query: 103 FRLVGRVVAKVLQDGRLLDLPLSTAFYKLILGQELDLFDIISFDAELGKTLQELQVLVER 282 FR +GR++ L L + L+ K++LG++++ D FD + ++L++L +L Sbjct: 2522 FRNIGRILGLCLLQNELCPITLNRHVIKVLLGRKVNWHDFAFFDPVMYESLRQL-ILAS- 2579 Query: 283 KRFFESSCGKDQLKVADLRFRGAPIEDLCLDFTLPGFPDYVLKEGEQNTIVNIHNLEEYV 462 +SS DL F DLC + G L N V N+ EYV Sbjct: 2580 ----QSSDADAVFSAMDLAF----AIDLCKE---EGGGQVELIPNGVNIPVTPQNVYEYV 2628 Query: 463 SLVVDATLKSGIMKQVEAFRSGFSQVFDISSLQIFSPQELDYLI 594 + + + + A R G V +SL+ + ++ L+ Sbjct: 2629 RKYAEHRMLVVAEQPLHAMRKGLLDVLPKNSLEDLTAEDFRLLV 2672
>EDD1_HUMAN (O95071) Ubiquitin-protein ligase EDD1 (EC 6.3.2.-) (Hyperplastic| discs protein homolog) (hHYD) (Progestin-induced protein) Length = 2799 Score = 37.7 bits (86), Expect = 0.025 Identities = 39/164 (23%), Positives = 69/164 (42%) Frame = +1 Query: 103 FRLVGRVVAKVLQDGRLLDLPLSTAFYKLILGQELDLFDIISFDAELGKTLQELQVLVER 282 FR +GR++ L L + L+ K++LG++++ D FD + ++L++L +L Sbjct: 2529 FRNIGRILGLCLLQNELCPITLNRHVIKVLLGRKVNWHDFAFFDPVMYESLRQL-ILAS- 2586 Query: 283 KRFFESSCGKDQLKVADLRFRGAPIEDLCLDFTLPGFPDYVLKEGEQNTIVNIHNLEEYV 462 +SS DL F DLC + G L N V N+ EYV Sbjct: 2587 ----QSSDADAVFSAMDLAF----AIDLCKE---EGGGQVELIPNGVNIPVTPQNVYEYV 2635 Query: 463 SLVVDATLKSGIMKQVEAFRSGFSQVFDISSLQIFSPQELDYLI 594 + + + + A R G V +SL+ + ++ L+ Sbjct: 2636 RKYAEHRMLVVAEQPLHAMRKGLLDVLPKNSLEDLTAEDFRLLV 2679
>HERC5_HUMAN (Q9UII4) HECT domain and RCC1-like domain-containing protein 5| (Cyclin-E-binding protein 1) Length = 1024 Score = 37.0 bits (84), Expect = 0.043 Identities = 38/147 (25%), Positives = 58/147 (39%), Gaps = 1/147 (0%) Frame = +1 Query: 157 DLPLSTAFYKLILGQELDLFDIISFDAELGKTLQELQVLVERKRFFESSCGKDQLKVADL 336 +LP A +K +L Q L D+ +LGK LQ L L + FE Sbjct: 785 NLPFPLALFKKLLDQMPSLEDLKELSPDLGKNLQTL--LDDEGDNFE------------- 829 Query: 337 RFRGAPIEDLCLDFTLP-GFPDYVLKEGEQNTIVNIHNLEEYVSLVVDATLKSGIMKQVE 513 E + F + D L + VN N +YVS ++ + E Sbjct: 830 -------EVFYIHFNVHWDRNDTNLIPNGSSITVNQTNKRDYVSKYINYIFNDSVKAVYE 882 Query: 514 AFRSGFSQVFDISSLQIFSPQELDYLI 594 FR GF ++ D +++F P+EL +I Sbjct: 883 EFRRGFYKMCDEDIIKLFHPEELKDVI 909
>YG1F_YEAST (P53214) Hypothetical 57.5 kDa protein in VMA7-RPS25A intergenic| region Length = 551 Score = 32.3 bits (72), Expect = 1.1 Identities = 51/200 (25%), Positives = 79/200 (39%), Gaps = 33/200 (16%) Frame = -2 Query: 545 SKTWLKPDLKASTCFI----IPDFSVASTTKETYSSRL*ILTIVFCSPSLRT*SGKPGRV 378 S + + P +ST +P F+VAST+ SS L + + S S T + Sbjct: 127 SSSSISPSSSSSTIISSSSSLPTFTVASTSSTVASSTLSTSSSLVISTSSSTFTFSSESS 186 Query: 377 KSKHKSSIG----------------APRNRKSATFS*SLPQLDSKNLL---RSTRTCNSC 255 S SSI +P + S S S S + L S+ + +S Sbjct: 187 SSLISSSISTSVSTSSVYVPSSSTSSPPSSSSELTSSSYSSSSSSSTLFSYSSSFSSSSS 246 Query: 254 SVFPSSASKEIMSNKSSSCPSISL*NAVDKGKSKSRPSCKTFATTRPTKRKYSTT----- 90 S SS+S S+ SSS ++S ++ S S PS + +++ PT ST+ Sbjct: 247 SSSSSSSSSSSSSSSSSSYFTLSTSSSSSIYSSSSYPSFSSSSSSNPTSSITSTSASSSI 306 Query: 89 -----LRNLLPSEVSTLEGQ 45 NL + S +EGQ Sbjct: 307 TPASEYSNLAKTITSIIEGQ 326
>SYA_PYRFU (Q8U425) Alanyl-tRNA synthetase (EC 6.1.1.7) (Alanine--tRNA ligase)| (AlaRS) Length = 914 Score = 32.0 bits (71), Expect = 1.4 Identities = 41/154 (26%), Positives = 68/154 (44%), Gaps = 17/154 (11%) Frame = +1 Query: 103 FRLVGRVVAKVLQDGRLLDLPLSTAFYKLI-LGQELDLFDIISFDA-ELGKTLQELQVL- 273 F L VV ++ G L L + + L LG E+ L +I++ EL T E + + Sbjct: 350 FMLADGVVPSNVKAGYLARLLIRKSIRHLRELGLEVPLAEIVAMHIKELSPTFPEFKEME 409 Query: 274 --------VERKRFFES-SCGKDQLK--VADLRFRGA---PIEDLCLDFTLPGFPDYVLK 411 +E K++ E+ G D +K +A L+ +GA P+E L + G ++K Sbjct: 410 DIILEMIELEEKKYAETLRRGSDLVKREIAKLKKKGANEIPLEKLITFYESHGLTPEIVK 469 Query: 412 EGEQNTIVNIHNLEEYVSLVVDATLKSGIMKQVE 513 E + V +H + + SLV K K+ E Sbjct: 470 EIAEKEGVKVHIPDNFYSLVAKEAEKQVEEKEEE 503
>DNAK_CAMJR (Q5HV33) Chaperone protein dnaK (Heat shock protein 70) (Heat shock| 70 kDa protein) (HSP70) Length = 623 Score = 30.0 bits (66), Expect = 5.3 Identities = 22/78 (28%), Positives = 33/78 (42%), Gaps = 1/78 (1%) Frame = -2 Query: 269 TCNSCSVFPSSASKEIMSNKSSSCPSISL*NAVDKGKSKSRPSCKTFATTRPTKRKYS-T 93 T NSC +++ NK + S+ DKG+ S K A T P K YS Sbjct: 11 TTNSCVAVYERGESKVIPNKEGKNTTPSVVAFTDKGEVLVGDSAKRQAVTNPEKTIYSIK 70 Query: 92 TLRNLLPSEVSTLEGQGR 39 + L+ +E + E + R Sbjct: 71 RIMGLMINEDAAKEAKNR 88
>DNAK_CAMJE (O69298) Chaperone protein dnaK (Heat shock protein 70) (Heat shock| 70 kDa protein) (HSP70) Length = 623 Score = 30.0 bits (66), Expect = 5.3 Identities = 22/78 (28%), Positives = 33/78 (42%), Gaps = 1/78 (1%) Frame = -2 Query: 269 TCNSCSVFPSSASKEIMSNKSSSCPSISL*NAVDKGKSKSRPSCKTFATTRPTKRKYS-T 93 T NSC +++ NK + S+ DKG+ S K A T P K YS Sbjct: 11 TTNSCVAVYERGESKVIPNKEGKNTTPSVVAFTDKGEVLVGDSAKRQAVTNPEKTIYSIK 70 Query: 92 TLRNLLPSEVSTLEGQGR 39 + L+ +E + E + R Sbjct: 71 RIMGLMINEDAAKEAKNR 88
>AGA1_YEAST (P32323) A-agglutinin attachment subunit precursor| Length = 725 Score = 30.0 bits (66), Expect = 5.3 Identities = 35/143 (24%), Positives = 56/143 (39%) Frame = -2 Query: 482 VASTTKETYSSRL*ILTIVFCSPSLRT*SGKPGRVKSKHKSSIGAPRNRKSATFS*SLPQ 303 V ST T SS ++ S S + S P + S+ + + ++T S S Sbjct: 169 VTSTLSSTTSSNPTTTSLSSTSTSPSSTSTSPSSTSTSSSST--STSSSSTSTSSSSTST 226 Query: 302 LDSKNLLRSTRTCNSCSVFPSSASKEIMSNKSSSCPSISL*NAVDKGKSKSRPSCKTFAT 123 S S+ T S S +S S+ S SSS + + + + PS K+ + Sbjct: 227 SPSSTSTSSSLTSTSSS--STSTSQSSTSTSSSSTSTSPSSTSTSSSSTSTSPSSKSTSA 284 Query: 122 TRPTKRKYSTTLRNLLPSEVSTL 54 + + YST+ L S TL Sbjct: 285 SSTSTSSYSTSTSPSLTSSSPTL 307
>RASA3_HUMAN (Q14644) Ras GTPase-activating protein 3 (GAP1(IP4BP)) (Ins| P4-binding protein) Length = 834 Score = 29.6 bits (65), Expect = 6.9 Identities = 21/71 (29%), Positives = 33/71 (46%), Gaps = 4/71 (5%) Frame = +1 Query: 298 SSCGKDQLKVADLRFRGAP----IEDLCLDFTLPGFPDYVLKEGEQNTIVNIHNLEEYVS 465 S C + +K+A + + IE++C LK+GE N N+ NL +YV Sbjct: 377 SKCIDETMKLAGMHYLHVTLKPAIEEICQSHKPCEIDPVKLKDGE-NLENNMENLRQYVD 435 Query: 466 LVVDATLKSGI 498 V A +SG+ Sbjct: 436 RVFHAITESGV 446
>UBIB_NEIMB (Q9K0N0) Probable ubiquinone biosynthesis protein ubiB| Length = 503 Score = 29.6 bits (65), Expect = 6.9 Identities = 22/81 (27%), Positives = 38/81 (46%) Frame = +1 Query: 124 VAKVLQDGRLLDLPLSTAFYKLILGQELDLFDIISFDAELGKTLQELQVLVERKRFFESS 303 V ++ DG+ L A + L ELDL + ++LG+ Q +L+ K F++ Sbjct: 172 VERLFADGKRLKPREVVAEFDKYLHDELDLMREAANASQLGRNFQNSDMLIVPKVFYD-Y 230 Query: 304 CGKDQLKVADLRFRGAPIEDL 366 C D L + + G P+ D+ Sbjct: 231 CTSDVLTIEWM--DGTPVSDI 249
>MSC3_YEAST (Q05812) Meiotic sister-chromatid recombination protein 3| Length = 728 Score = 29.6 bits (65), Expect = 6.9 Identities = 17/69 (24%), Positives = 30/69 (43%) Frame = -2 Query: 224 IMSNKSSSCPSISL*NAVDKGKSKSRPSCKTFATTRPTKRKYSTTLRNLLPSEVSTLEGQ 45 + N S P+ S + +G + ++PS T P + L+ + S ++ GQ Sbjct: 575 VTRNAEESFPAAS----ISEGVTTAKPSSNEGVMTNPVVTDSPSPLQQQIDSTTASSNGQ 630 Query: 44 GRGNXPRGA 18 +GN P A Sbjct: 631 SQGNVPTSA 639
>XYNC_PSEFL (P23031) Alpha-L-arabinofuranosidase C precursor (EC 3.2.1.55)| (Xylanase C) Length = 571 Score = 29.3 bits (64), Expect = 9.0 Identities = 18/47 (38%), Positives = 27/47 (57%) Frame = -2 Query: 332 SATFS*SLPQLDSKNLLRSTRTCNSCSVFPSSASKEIMSNKSSSCPS 192 SAT + LP +DS +++ T +C SS+S + S+ SSS PS Sbjct: 273 SATTAEGLPNIDSLSVVGGTVRAGNCGSVSSSSSVQ-SSSSSSSTPS 318
>PTH_THET8 (Q5SHZ2) Peptidyl-tRNA hydrolase (EC 3.1.1.29) (PTH)| Length = 183 Score = 29.3 bits (64), Expect = 9.0 Identities = 23/73 (31%), Positives = 35/73 (47%), Gaps = 12/73 (16%) Frame = +1 Query: 4 GNLIQAPLGLFPRP-WPSNVDTSEGSRFLKVVEYFRLVGRVVAKVLQDGRL--------- 153 G ++ LGL RP + V +EG FLK + Y+ L GR VA + + ++ Sbjct: 22 GFMVLDRLGLSFRPRGEALVAEAEGGLFLKPLTYYNLTGRAVAPLARFYKIPPERILVVH 81 Query: 154 --LDLPLSTAFYK 186 +DLPL +K Sbjct: 82 DEMDLPLGRIRFK 94
>PTH_THET2 (Q72IA8) Peptidyl-tRNA hydrolase (EC 3.1.1.29) (PTH)| Length = 183 Score = 29.3 bits (64), Expect = 9.0 Identities = 23/73 (31%), Positives = 35/73 (47%), Gaps = 12/73 (16%) Frame = +1 Query: 4 GNLIQAPLGLFPRP-WPSNVDTSEGSRFLKVVEYFRLVGRVVAKVLQDGRL--------- 153 G ++ LGL RP + V +EG FLK + Y+ L GR VA + + ++ Sbjct: 22 GFMVLDRLGLSFRPRGEALVAEAEGGLFLKPLTYYNLTGRAVAPLARFYKIPPERILVVH 81 Query: 154 --LDLPLSTAFYK 186 +DLPL +K Sbjct: 82 DEMDLPLGRIRFK 94
>XYNB_PSEFL (P23030) Endo-1,4-beta-xylanase B precursor (EC 3.2.1.8) (Xylanase| B) (1,4-beta-D-xylan xylanohydrolase B) Length = 592 Score = 29.3 bits (64), Expect = 9.0 Identities = 16/44 (36%), Positives = 25/44 (56%) Frame = -2 Query: 332 SATFS*SLPQLDSKNLLRSTRTCNSCSVFPSSASKEIMSNKSSS 201 SAT + LP +DS +++ T +C SS+S + S+ SSS Sbjct: 273 SATTAEGLPNIDSLSVVGGTVRAGNCGSVSSSSSVQSSSSSSSS 316
>ZN385_HUMAN (Q96PM9) Zinc finger protein 385 (Hematopoietic zinc finger| protein) (Retinal zinc finger protein) Length = 366 Score = 29.3 bits (64), Expect = 9.0 Identities = 17/41 (41%), Positives = 23/41 (56%) Frame = -2 Query: 398 SGKPGRVKSKHKSSIGAPRNRKSATFS*SLPQLDSKNLLRS 276 +GKP + S+HK S GA + TFS LP+ + LL S Sbjct: 270 AGKPNPLLSRHKKSRGAGELAGTLTFSKELPKSLAGGLLPS 310 Database: uniprot_sprot.fasta Posted date: May 25, 2006 5:36 PM Number of letters in database: 80,573,946 Number of sequences in database: 219,361 Lambda K H 0.318 0.135 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 75,726,405 Number of Sequences: 219361 Number of extensions: 1458937 Number of successful extensions: 4589 Number of sequences better than 10.0: 63 Number of HSP's better than 10.0 without gapping: 4402 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 4545 length of database: 80,573,946 effective HSP length: 106 effective length of database: 57,321,680 effective search space used: 5216272880 frameshift window, decay const: 50, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
