ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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| Clone Name | bags9b03 |
|---|---|
| Clone Library Name | barley_pub |
>IMA1A_ORYSA (Q71VM4) Importin alpha-1a subunit| Length = 526 Score = 320 bits (819), Expect(2) = 4e-89 Identities = 166/194 (85%), Positives = 176/194 (90%) Frame = +3 Query: 57 IQSVIDAGVCPRLVELLLHPSPSVLIPALRTVGNIVTGDDSQTQCIIDHQALGCLLSLLT 236 IQ+VI+AGVCPRLVELLLHPSPSVLIPALRTVGNIVTGDD+QTQCIIDHQAL CLLSLLT Sbjct: 277 IQAVIEAGVCPRLVELLLHPSPSVLIPALRTVGNIVTGDDAQTQCIIDHQALPCLLSLLT 336 Query: 237 ENHKKSIKKEACWTVSNITAGNKDQIQAVITAGIIFPLVHLLQTAEFDIKKEAAWAISNA 416 +N KKSIKKEACWT+SNITAGNKDQIQAVI AGII PLV+LLQTAEFDIKKEAAWAISNA Sbjct: 337 QNLKKSIKKEACWTISNITAGNKDQIQAVINAGIIGPLVNLLQTAEFDIKKEAAWAISNA 396 Query: 417 TSGGSHDQIKYLVSEGCIKXXXXXXXXXXXRIVTVCLEGLENILKVGETDKNLGASGEGN 596 TSGGSHDQIKYLVSEGCIK RIVTVCLEGLENILKVGETDK L A+G+ N Sbjct: 397 TSGGSHDQIKYLVSEGCIKPLCDLLICPDIRIVTVCLEGLENILKVGETDKTL-AAGDVN 455 Query: 597 VYAQMIDEAEGLEK 638 V++QMIDEAEGLEK Sbjct: 456 VFSQMIDEAEGLEK 469 Score = 56.6 bits (135), Expect = 6e-08 Identities = 41/133 (30%), Positives = 67/133 (50%) Frame = +3 Query: 66 VIDAGVCPRLVELLLHPSPSVLIPALRTVGNIVTGDDSQTQCIIDHQALGCLLSLLTENH 245 VID G P V+LL S V A+ +GN+ ++ + AL LL+ L E+ Sbjct: 154 VIDHGAVPIFVKLLGSSSDDVREQAVWALGNVAGDSPKCRDLVLANGALLPLLAQLNEHT 213 Query: 246 KKSIKKEACWTVSNITAGNKDQIQAVITAGIIFPLVHLLQTAEFDIKKEAAWAISNATSG 425 K S+ + A WT+SN G K Q T + L L+ + + ++ +A WA+S S Sbjct: 214 KLSMLRNATWTLSNFCRG-KPQPSFEQTRPALPALARLIHSNDEEVLTDACWALS-YLSD 271 Query: 426 GSHDQIKYLVSEG 464 G++D+I+ ++ G Sbjct: 272 GTNDKIQAVIEAG 284 Score = 33.1 bits (74), Expect = 0.72 Identities = 18/54 (33%), Positives = 31/54 (57%), Gaps = 1/54 (1%) Frame = +3 Query: 312 IQAVITAGIIFPLVHLLQTAEF-DIKKEAAWAISNATSGGSHDQIKYLVSEGCI 470 I+ VI +G++ V L +F ++ EAAWA++N SG S + K ++ G + Sbjct: 108 IEEVIQSGVVPRFVQFLTREDFPQLQFEAAWALTNIASGTS-ENTKVVIDHGAV 160 Score = 28.5 bits (62), Expect(2) = 4e-89 Identities = 12/18 (66%), Positives = 13/18 (72%) Frame = +2 Query: 2 LTXACWALSYLSEAPMXK 55 LT ACWALSYLS+ K Sbjct: 259 LTDACWALSYLSDGTNDK 276
>IMA1B_ORYSA (Q9SLX0) Importin alpha-1b subunit| Length = 534 Score = 306 bits (783), Expect(2) = 6e-85 Identities = 156/194 (80%), Positives = 171/194 (88%) Frame = +3 Query: 57 IQSVIDAGVCPRLVELLLHPSPSVLIPALRTVGNIVTGDDSQTQCIIDHQALGCLLSLLT 236 IQ+VI++GV PRLVELL+HPS SVLIPALRTVGNIVTGDD QTQC+IDHQAL CLL+LLT Sbjct: 283 IQAVIESGVFPRLVELLMHPSASVLIPALRTVGNIVTGDDMQTQCVIDHQALPCLLNLLT 342 Query: 237 ENHKKSIKKEACWTVSNITAGNKDQIQAVITAGIIFPLVHLLQTAEFDIKKEAAWAISNA 416 NHKKSIKKEACWT+SNITAGN++QIQAVI A II PLVHLLQTAEFDIKKEAAWAISNA Sbjct: 343 NNHKKSIKKEACWTISNITAGNREQIQAVINANIIAPLVHLLQTAEFDIKKEAAWAISNA 402 Query: 417 TSGGSHDQIKYLVSEGCIKXXXXXXXXXXXRIVTVCLEGLENILKVGETDKNLGASGEGN 596 TSGG+HDQIKYLV++GCIK RIVTVCLEGLENILKVGE +KNLGA G+ N Sbjct: 403 TSGGTHDQIKYLVAQGCIKPLCDLLVCPDPRIVTVCLEGLENILKVGEAEKNLGA-GDVN 461 Query: 597 VYAQMIDEAEGLEK 638 YAQMID+AEGLEK Sbjct: 462 SYAQMIDDAEGLEK 475 Score = 58.9 bits (141), Expect = 1e-08 Identities = 39/137 (28%), Positives = 70/137 (51%), Gaps = 4/137 (2%) Frame = +3 Query: 66 VIDAGVCPRLVELLLHPSPSVLIPALRTVGNIVTGDDSQTQCIIDHQALGCLLSLLTENH 245 V+++G P V+LL PS V A+ +GN+ ++ L LL L E+ Sbjct: 160 VVESGAVPIFVKLLSSPSEDVREQAVWALGNVAGDSPKCRDLVLASGGLYPLLQQLNEHA 219 Query: 246 KKSIKKEACWTVSNITAG----NKDQIQAVITAGIIFPLVHLLQTAEFDIKKEAAWAISN 413 K S+ + A WT+SN G N +Q++ ++A L L+ + + ++ +A WA+S Sbjct: 220 KLSMLRNATWTLSNFCRGKPQPNFEQVKPALSA-----LQRLIHSQDEEVLTDACWALS- 273 Query: 414 ATSGGSHDQIKYLVSEG 464 S G++D+I+ ++ G Sbjct: 274 YLSDGTNDKIQAVIESG 290 Score = 35.0 bits (79), Expect = 0.19 Identities = 19/54 (35%), Positives = 31/54 (57%), Gaps = 1/54 (1%) Frame = +3 Query: 312 IQAVITAGIIFPLVHLLQTAEF-DIKKEAAWAISNATSGGSHDQIKYLVSEGCI 470 I+ VI G++ + LQ ++ ++ EAAWA++N SG S D K +V G + Sbjct: 114 IEEVINTGVVPRFIAFLQREDYPQLQFEAAWALTNIASGTS-DNTKVVVESGAV 166 Score = 28.5 bits (62), Expect(2) = 6e-85 Identities = 12/18 (66%), Positives = 13/18 (72%) Frame = +2 Query: 2 LTXACWALSYLSEAPMXK 55 LT ACWALSYLS+ K Sbjct: 265 LTDACWALSYLSDGTNDK 282
>IMA1_ARATH (Q96321) Importin alpha-1 subunit (Karyopherin alpha-1 subunit)| (KAP alpha) Length = 532 Score = 293 bits (749), Expect(2) = 5e-81 Identities = 148/194 (76%), Positives = 164/194 (84%) Frame = +3 Query: 57 IQSVIDAGVCPRLVELLLHPSPSVLIPALRTVGNIVTGDDSQTQCIIDHQALGCLLSLLT 236 IQ+VI AGV P+LVELLLH SPSVLIPALRTVGNIVTGDD QTQC+I+ AL CL +LLT Sbjct: 277 IQTVIQAGVVPKLVELLLHHSPSVLIPALRTVGNIVTGDDIQTQCVINSGALPCLANLLT 336 Query: 237 ENHKKSIKKEACWTVSNITAGNKDQIQAVITAGIIFPLVHLLQTAEFDIKKEAAWAISNA 416 +NHKKSIKKEACWT+SNITAGNKDQIQ V+ A +I PLV LLQ AEFDIKKEAAWAISNA Sbjct: 337 QNHKKSIKKEACWTISNITAGNKDQIQTVVEANLISPLVSLLQNAEFDIKKEAAWAISNA 396 Query: 417 TSGGSHDQIKYLVSEGCIKXXXXXXXXXXXRIVTVCLEGLENILKVGETDKNLGASGEGN 596 TSGGSHDQIKYLV +GCIK RI+TVCLEGLENILKVGE +KNLG +G+ N Sbjct: 397 TSGGSHDQIKYLVEQGCIKPLCDLLVCPDPRIITVCLEGLENILKVGEAEKNLGHTGDMN 456 Query: 597 VYAQMIDEAEGLEK 638 YAQ+ID+AEGLEK Sbjct: 457 YYAQLIDDAEGLEK 470 Score = 64.3 bits (155), Expect = 3e-10 Identities = 40/135 (29%), Positives = 67/135 (49%), Gaps = 5/135 (3%) Frame = +3 Query: 57 IQSVIDAGVCPRLVELLLHPS-PSVLIPALRTVGNIVTGDDSQTQCIIDHQALGCLLSLL 233 I+ VI AGV PR VE L P++ A + NI +G T+ +IDH A+ + LL Sbjct: 108 IEEVISAGVVPRFVEFLKKEDYPAIQFEAAWALTNIASGTSDHTKVVIDHNAVPIFVQLL 167 Query: 234 TENHKKSIKKEACWTVSNITAGNKDQIQAVITAGIIFPLVHLL-QTAEFDIKKEAAWAIS 410 + ++++A W + N+ + V+ G + PL++ L + A+ + + A W +S Sbjct: 168 A-SPSDDVREQAVWALGNVAGDSPRCRDLVLGCGALLPLLNQLNEHAKLSMLRNATWTLS 226 Query: 411 NATSGGSH---DQIK 446 N G DQ+K Sbjct: 227 NFCRGKPQPHFDQVK 241 Score = 58.5 bits (140), Expect = 2e-08 Identities = 45/144 (31%), Positives = 74/144 (51%), Gaps = 9/144 (6%) Frame = +3 Query: 66 VIDAGVCPRLVELLLHPSPSVLIPALRTVGNIVTGDDSQTQCIIDHQALGC-----LLSL 230 VID P V+LL PS V A+ +GN V GD + + ++ LGC LL+ Sbjct: 154 VIDHNAVPIFVQLLASPSDDVREQAVWALGN-VAGDSPRCRDLV----LGCGALLPLLNQ 208 Query: 231 LTENHKKSIKKEACWTVSNITAGNK----DQIQAVITAGIIFPLVHLLQTAEFDIKKEAA 398 L E+ K S+ + A WT+SN G DQ++ + A L L+ + + ++ +A Sbjct: 209 LNEHAKLSMLRNATWTLSNFCRGKPQPHFDQVKPALPA-----LERLIHSDDEEVLTDAC 263 Query: 399 WAISNATSGGSHDQIKYLVSEGCI 470 WA+S S G++D+I+ ++ G + Sbjct: 264 WALS-YLSDGTNDKIQTVIQAGVV 286 Score = 28.5 bits (62), Expect(2) = 5e-81 Identities = 12/18 (66%), Positives = 13/18 (72%) Frame = +2 Query: 2 LTXACWALSYLSEAPMXK 55 LT ACWALSYLS+ K Sbjct: 259 LTDACWALSYLSDGTNDK 276
>IMA_LYCES (O22478) Importin alpha subunit (Karyopherin alpha subunit) (KAP| alpha) Length = 527 Score = 292 bits (748), Expect(2) = 7e-81 Identities = 149/194 (76%), Positives = 168/194 (86%) Frame = +3 Query: 57 IQSVIDAGVCPRLVELLLHPSPSVLIPALRTVGNIVTGDDSQTQCIIDHQALGCLLSLLT 236 IQ+VI+AGVC RLVELLLH SPSVLIPALRTVGNIVTGDD QTQ +IDH AL CL++LLT Sbjct: 278 IQAVIEAGVCSRLVELLLHSSPSVLIPALRTVGNIVTGDDIQTQVMIDHHALPCLVNLLT 337 Query: 237 ENHKKSIKKEACWTVSNITAGNKDQIQAVITAGIIFPLVHLLQTAEFDIKKEAAWAISNA 416 +N+KKSIKKEACWT+SNITAGN++QIQ VI AGII PLV+LLQ AEF+IKKEAAWAISNA Sbjct: 338 QNYKKSIKKEACWTISNITAGNRNQIQIVIEAGIIAPLVYLLQNAEFEIKKEAAWAISNA 397 Query: 417 TSGGSHDQIKYLVSEGCIKXXXXXXXXXXXRIVTVCLEGLENILKVGETDKNLGASGEGN 596 TSGG+HDQIK+LVS+GCIK RIVTVCLEGLENILK+GE DK+LG + N Sbjct: 398 TSGGNHDQIKFLVSQGCIKPLCDLLVCPDPRIVTVCLEGLENILKIGEADKDLGNTEGVN 457 Query: 597 VYAQMIDEAEGLEK 638 VYAQ+IDEAEGLEK Sbjct: 458 VYAQLIDEAEGLEK 471 Score = 61.6 bits (148), Expect = 2e-09 Identities = 42/133 (31%), Positives = 65/133 (48%) Frame = +3 Query: 66 VIDAGVCPRLVELLLHPSPSVLIPALRTVGNIVTGDDSQTQCIIDHQALGCLLSLLTENH 245 VID G P + LL PS V A+ +GNI ++ H AL LL+ E Sbjct: 155 VIDYGSVPIFIRLLSSPSDDVREQAVWALGNIAGDSPKYRDLVLGHGALVALLAQFNEQA 214 Query: 246 KKSIKKEACWTVSNITAGNKDQIQAVITAGIIFPLVHLLQTAEFDIKKEAAWAISNATSG 425 K S+ + A WT+SN G K Q T + L L+ + + ++ +A WA+S S Sbjct: 215 KLSMLRNATWTLSNFCRG-KPQPLFEQTKAALPTLGRLIHSNDEEVLTDACWALS-YLSD 272 Query: 426 GSHDQIKYLVSEG 464 G++D+I+ ++ G Sbjct: 273 GTNDKIQAVIEAG 285 Score = 30.4 bits (67), Expect = 4.6 Identities = 17/54 (31%), Positives = 31/54 (57%), Gaps = 1/54 (1%) Frame = +3 Query: 312 IQAVITAGIIFPLVHLLQTAEF-DIKKEAAWAISNATSGGSHDQIKYLVSEGCI 470 I+ VI +G++ V L ++ ++ EAAWA++N SG S + K ++ G + Sbjct: 109 IEEVIQSGVVPRFVEFLARDDYPQLQFEAAWALTNIASGTS-ENTKVVIDYGSV 161 Score = 28.5 bits (62), Expect(2) = 7e-81 Identities = 12/18 (66%), Positives = 13/18 (72%) Frame = +2 Query: 2 LTXACWALSYLSEAPMXK 55 LT ACWALSYLS+ K Sbjct: 260 LTDACWALSYLSDGTNDK 277
>IMA2_ARATH (O04294) Importin alpha-2 subunit (Karyopherin alpha-2 subunit)| (KAP alpha) Length = 531 Score = 279 bits (714), Expect(2) = 7e-77 Identities = 140/194 (72%), Positives = 163/194 (84%) Frame = +3 Query: 57 IQSVIDAGVCPRLVELLLHPSPSVLIPALRTVGNIVTGDDSQTQCIIDHQALGCLLSLLT 236 IQ+VI+AGV PRL++LL H SPSVLIPALRT+GNIVTGDD QTQ ++D QAL CLL+LL Sbjct: 280 IQAVIEAGVVPRLIQLLGHSSPSVLIPALRTIGNIVTGDDLQTQMVLDQQALPCLLNLLK 339 Query: 237 ENHKKSIKKEACWTVSNITAGNKDQIQAVITAGIIFPLVHLLQTAEFDIKKEAAWAISNA 416 N+KKSIKKEACWT+SNITAGN DQIQAVI AGII LV +LQ+AEF++KKEAAW ISNA Sbjct: 340 NNYKKSIKKEACWTISNITAGNADQIQAVIDAGIIQSLVWVLQSAEFEVKKEAAWGISNA 399 Query: 417 TSGGSHDQIKYLVSEGCIKXXXXXXXXXXXRIVTVCLEGLENILKVGETDKNLGASGEGN 596 TSGG+HDQIK++VS+GCIK ++VTVCLE LENIL VGE +KNLG +GE N Sbjct: 400 TSGGTHDQIKFMVSQGCIKPLCDLLTCPDLKVVTVCLEALENILVVGEAEKNLGHTGEDN 459 Query: 597 VYAQMIDEAEGLEK 638 +YAQMIDEAEGLEK Sbjct: 460 LYAQMIDEAEGLEK 473 Score = 58.5 bits (140), Expect = 2e-08 Identities = 41/165 (24%), Positives = 75/165 (45%), Gaps = 4/165 (2%) Frame = +3 Query: 66 VIDAGVCPRLVELLLHPSPSVLIPALRTVGNIVTGDDSQTQCIIDHQALGCLLSLLTENH 245 +I++G P ++LL S V A+ +GN+ ++ + A+ LLS EN Sbjct: 157 IIESGAVPIFIQLLSSASEDVREQAVWALGNVAGDSPKCRDLVLSYGAMTPLLSQFNENT 216 Query: 246 KKSIKKEACWTVSNITAGNK----DQIQAVITAGIIFPLVHLLQTAEFDIKKEAAWAISN 413 K S+ + A WT+SN G +Q Q + L L+Q+ + ++ +A WA+S Sbjct: 217 KLSMLRNATWTLSNFCRGKPPPAFEQTQPALPV-----LERLVQSMDEEVLTDACWALS- 270 Query: 414 ATSGGSHDQIKYLVSEGCIKXXXXXXXXXXXRIVTVCLEGLENIL 548 S S+D+I+ ++ G + ++ L + NI+ Sbjct: 271 YLSDNSNDKIQAVIEAGVVPRLIQLLGHSSPSVLIPALRTIGNIV 315 Score = 30.0 bits (66), Expect = 6.1 Identities = 16/54 (29%), Positives = 30/54 (55%), Gaps = 1/54 (1%) Frame = +3 Query: 312 IQAVITAGIIFPLVHLLQTAEFD-IKKEAAWAISNATSGGSHDQIKYLVSEGCI 470 I V+ +G++ +V L +F ++ EAAWA++N SG S + ++ G + Sbjct: 111 INEVVQSGVVPRVVKFLSRDDFPKLQFEAAWALTNIASGTS-ENTNVIIESGAV 163 Score = 28.1 bits (61), Expect(2) = 7e-77 Identities = 11/13 (84%), Positives = 12/13 (92%) Frame = +2 Query: 2 LTXACWALSYLSE 40 LT ACWALSYLS+ Sbjct: 262 LTDACWALSYLSD 274
>IMA7_MOUSE (O35345) Importin alpha-7 subunit (Karyopherin alpha-6 subunit)| (Importin alpha S2) Length = 533 Score = 210 bits (534), Expect(2) = 1e-56 Identities = 115/194 (59%), Positives = 140/194 (72%) Frame = +3 Query: 57 IQSVIDAGVCPRLVELLLHPSPSVLIPALRTVGNIVTGDDSQTQCIIDHQALGCLLSLLT 236 IQ+VID+GVC RLVELL+H V PALR VGNIVTGDD QTQ I++ AL CLL LL+ Sbjct: 284 IQAVIDSGVCRRLVELLMHNDYKVASPALRAVGNIVTGDDIQTQVILNCSALPCLLHLLS 343 Query: 237 ENHKKSIKKEACWTVSNITAGNKDQIQAVITAGIIFPLVHLLQTAEFDIKKEAAWAISNA 416 + K+SI+KEACWT+SNITAGN+ QIQAVI A I L+ +LQ AEF +KEAAWAI+NA Sbjct: 344 SS-KESIRKEACWTISNITAGNRAQIQAVIDANIFPVLIEILQKAEFRTRKEAAWAITNA 402 Query: 417 TSGGSHDQIKYLVSEGCIKXXXXXXXXXXXRIVTVCLEGLENILKVGETDKNLGASGEGN 596 TSGG+ +QI+YLVS GCIK +IV V L GLENIL++GE + SG N Sbjct: 403 TSGGTPEQIRYLVSLGCIKPLCDLLTVMDSKIVQVALNGLENILRLGEQESKRSGSGV-N 461 Query: 597 VYAQMIDEAEGLEK 638 Y +I+EA GL+K Sbjct: 462 PYCGLIEEAYGLDK 475 Score = 58.5 bits (140), Expect = 2e-08 Identities = 39/161 (24%), Positives = 76/161 (47%) Frame = +3 Query: 66 VIDAGVCPRLVELLLHPSPSVLIPALRTVGNIVTGDDSQTQCIIDHQALGCLLSLLTENH 245 VI+AG P +ELL V A+ +GNI +++ L LL+LLT++ Sbjct: 160 VIEAGAVPIFIELLNSDFEDVQEQAVWALGNIAGDSSLCRDYVLNCSILNPLLTLLTKST 219 Query: 246 KKSIKKEACWTVSNITAGNKDQIQAVITAGIIFPLVHLLQTAEFDIKKEAAWAISNATSG 425 + ++ + A W +SN+ G + + + L LL +++ D+ +A WA+S S Sbjct: 220 RLTMTRNAVWALSNLCRGKNPPPEFAKVSPCLPVLSRLLFSSDSDLLADACWALS-YLSD 278 Query: 426 GSHDQIKYLVSEGCIKXXXXXXXXXXXRIVTVCLEGLENIL 548 G +++I+ ++ G + ++ + L + NI+ Sbjct: 279 GPNEKIQAVIDSGVCRRLVELLMHNDYKVASPALRAVGNIV 319 Score = 29.6 bits (65), Expect(2) = 1e-56 Identities = 12/18 (66%), Positives = 13/18 (72%) Frame = +2 Query: 2 LTXACWALSYLSEAPMXK 55 L ACWALSYLS+ P K Sbjct: 266 LADACWALSYLSDGPNEK 283 Score = 29.6 bits (65), Expect = 7.9 Identities = 17/53 (32%), Positives = 29/53 (54%), Gaps = 1/53 (1%) Frame = +3 Query: 315 QAVITAGIIFPLVHLLQTAE-FDIKKEAAWAISNATSGGSHDQIKYLVSEGCI 470 + + T G++ V L+ E ++ EAAWA++N SG S Q K ++ G + Sbjct: 115 EVINTPGVVDRFVEFLKRNENCTLQFEAAWALTNIASGTS-QQTKIVIEAGAV 166
>IMA1_RAT (P83953) Importin alpha-1 subunit (Karyopherin alpha-1 subunit)| (Importin alpha 5) Length = 538 Score = 208 bits (530), Expect(2) = 4e-56 Identities = 116/194 (59%), Positives = 139/194 (71%) Frame = +3 Query: 57 IQSVIDAGVCPRLVELLLHPSPSVLIPALRTVGNIVTGDDSQTQCIIDHQALGCLLSLLT 236 IQ+VIDAGVC RLVELL+H V+ PALR VGNIVTGDD QTQ I++ AL LL LL+ Sbjct: 289 IQAVIDAGVCRRLVELLMHNDYKVVSPALRAVGNIVTGDDIQTQVILNCSALQSLLHLLS 348 Query: 237 ENHKKSIKKEACWTVSNITAGNKDQIQAVITAGIIFPLVHLLQTAEFDIKKEAAWAISNA 416 + K+SIKKEACWT+SNITAGN+ QIQ VI A + L+ +LQTAEF +KEAAWAI+NA Sbjct: 349 -SPKESIKKEACWTISNITAGNRAQIQTVIDANMFPALISILQTAEFRTRKEAAWAITNA 407 Query: 417 TSGGSHDQIKYLVSEGCIKXXXXXXXXXXXRIVTVCLEGLENILKVGETDKNLGASGEGN 596 TSGGS +QIKYLV GCIK +IV V L GLENIL++GE + SG N Sbjct: 408 TSGGSAEQIKYLVELGCIKPLCDLLTVMDAKIVQVALNGLENILRLGEQEAKRNGSGI-N 466 Query: 597 VYAQMIDEAEGLEK 638 Y +I+EA GL+K Sbjct: 467 PYCALIEEAYGLDK 480 Score = 58.9 bits (141), Expect = 1e-08 Identities = 40/161 (24%), Positives = 73/161 (45%) Frame = +3 Query: 66 VIDAGVCPRLVELLLHPSPSVLIPALRTVGNIVTGDDSQTQCIIDHQALGCLLSLLTENH 245 VI AG P +ELL V A+ +GNI ++D L LL L ++ + Sbjct: 165 VIQAGAVPIFIELLSSEFEDVQEQAVWALGNIAGDSTMCRDYVLDCNILPPLLQLFSKQN 224 Query: 246 KKSIKKEACWTVSNITAGNKDQIQAVITAGIIFPLVHLLQTAEFDIKKEAAWAISNATSG 425 + ++ + A W +SN+ G + + + L LL ++ D+ +A WA+S S Sbjct: 225 RLTMTRNAVWALSNLCRGKSPPPEFAKVSPCLNVLSWLLFVSDTDVLADACWALS-YLSD 283 Query: 426 GSHDQIKYLVSEGCIKXXXXXXXXXXXRIVTVCLEGLENIL 548 G +D+I+ ++ G + ++V+ L + NI+ Sbjct: 284 GPNDKIQAVIDAGVCRRLVELLMHNDYKVVSPALRAVGNIV 324 Score = 43.5 bits (101), Expect = 5e-04 Identities = 19/64 (29%), Positives = 36/64 (56%) Frame = +3 Query: 222 LSLLTENHKKSIKKEACWTVSNITAGNKDQIQAVITAGIIFPLVHLLQTAEFDIKKEAAW 401 + L +++ E+ W ++NI +GN Q + VI AG + + LL + D++++A W Sbjct: 132 VEFLKRKENCTLQFESAWVLTNIASGNSLQTRIVIQAGAVPIFIELLSSEFEDVQEQAVW 191 Query: 402 AISN 413 A+ N Sbjct: 192 ALGN 195 Score = 29.6 bits (65), Expect(2) = 4e-56 Identities = 12/18 (66%), Positives = 13/18 (72%) Frame = +2 Query: 2 LTXACWALSYLSEAPMXK 55 L ACWALSYLS+ P K Sbjct: 271 LADACWALSYLSDGPNDK 288
>IMA1_MOUSE (Q60960) Importin alpha-1 subunit (Karyopherin alpha-1 subunit)| (SRP1-beta) (RAG cohort protein 2) (Nucleoprotein interactor 1) (Importin alpha S1) Length = 538 Score = 208 bits (530), Expect(2) = 4e-56 Identities = 116/194 (59%), Positives = 139/194 (71%) Frame = +3 Query: 57 IQSVIDAGVCPRLVELLLHPSPSVLIPALRTVGNIVTGDDSQTQCIIDHQALGCLLSLLT 236 IQ+VIDAGVC RLVELL+H V+ PALR VGNIVTGDD QTQ I++ AL LL LL+ Sbjct: 289 IQAVIDAGVCRRLVELLMHNDYKVVSPALRAVGNIVTGDDIQTQVILNCSALQSLLHLLS 348 Query: 237 ENHKKSIKKEACWTVSNITAGNKDQIQAVITAGIIFPLVHLLQTAEFDIKKEAAWAISNA 416 + K+SIKKEACWT+SNITAGN+ QIQ VI A + L+ +LQTAEF +KEAAWAI+NA Sbjct: 349 -SPKESIKKEACWTISNITAGNRAQIQTVIDANMFPALISILQTAEFRTRKEAAWAITNA 407 Query: 417 TSGGSHDQIKYLVSEGCIKXXXXXXXXXXXRIVTVCLEGLENILKVGETDKNLGASGEGN 596 TSGGS +QIKYLV GCIK +IV V L GLENIL++GE + SG N Sbjct: 408 TSGGSAEQIKYLVELGCIKPLCDLLTVMDAKIVQVALNGLENILRLGEQEAKRNGSGI-N 466 Query: 597 VYAQMIDEAEGLEK 638 Y +I+EA GL+K Sbjct: 467 PYCALIEEAYGLDK 480 Score = 57.8 bits (138), Expect = 3e-08 Identities = 39/163 (23%), Positives = 75/163 (46%) Frame = +3 Query: 60 QSVIDAGVCPRLVELLLHPSPSVLIPALRTVGNIVTGDDSQTQCIIDHQALGCLLSLLTE 239 ++VI AG P +ELL V A+ +GNI +++ L LL L ++ Sbjct: 163 RNVIQAGAVPIFIELLSSEFEDVQEQAVWALGNIAGDSTMCRDYVLNCNILPPLLQLFSK 222 Query: 240 NHKKSIKKEACWTVSNITAGNKDQIQAVITAGIIFPLVHLLQTAEFDIKKEAAWAISNAT 419 ++ ++ + A W +SN+ G + + + L LL ++ D+ +A WA+S Sbjct: 223 QNRLTMTRNAVWALSNLCRGKSPPPEFAKVSPCLNVLSWLLFVSDTDVLADACWALS-YL 281 Query: 420 SGGSHDQIKYLVSEGCIKXXXXXXXXXXXRIVTVCLEGLENIL 548 S G +D+I+ ++ G + ++V+ L + NI+ Sbjct: 282 SDGPNDKIQAVIDAGVCRRLVELLMHNDYKVVSPALRAVGNIV 324 Score = 43.1 bits (100), Expect = 7e-04 Identities = 19/64 (29%), Positives = 36/64 (56%) Frame = +3 Query: 222 LSLLTENHKKSIKKEACWTVSNITAGNKDQIQAVITAGIIFPLVHLLQTAEFDIKKEAAW 401 + L +++ E+ W ++NI +GN Q + VI AG + + LL + D++++A W Sbjct: 132 VEFLKRKENCTLQFESAWVLTNIASGNSLQTRNVIQAGAVPIFIELLSSEFEDVQEQAVW 191 Query: 402 AISN 413 A+ N Sbjct: 192 ALGN 195 Score = 29.6 bits (65), Expect(2) = 4e-56 Identities = 12/18 (66%), Positives = 13/18 (72%) Frame = +2 Query: 2 LTXACWALSYLSEAPMXK 55 L ACWALSYLS+ P K Sbjct: 271 LADACWALSYLSDGPNDK 288
>IMA1_HUMAN (P52294) Importin alpha-1 subunit (Karyopherin alpha-1 subunit)| (SRP1-beta) (RAG cohort protein 2) (Nucleoprotein interactor 1) (NPI-1) Length = 538 Score = 208 bits (530), Expect(2) = 4e-56 Identities = 116/194 (59%), Positives = 139/194 (71%) Frame = +3 Query: 57 IQSVIDAGVCPRLVELLLHPSPSVLIPALRTVGNIVTGDDSQTQCIIDHQALGCLLSLLT 236 IQ+VIDAGVC RLVELL+H V+ PALR VGNIVTGDD QTQ I++ AL LL LL+ Sbjct: 289 IQAVIDAGVCRRLVELLMHNDYKVVSPALRAVGNIVTGDDIQTQVILNCSALQSLLHLLS 348 Query: 237 ENHKKSIKKEACWTVSNITAGNKDQIQAVITAGIIFPLVHLLQTAEFDIKKEAAWAISNA 416 + K+SIKKEACWT+SNITAGN+ QIQ VI A I L+ +LQTAEF +KEAAWAI+NA Sbjct: 349 -SPKESIKKEACWTISNITAGNRAQIQTVIDANIFPALISILQTAEFRTRKEAAWAITNA 407 Query: 417 TSGGSHDQIKYLVSEGCIKXXXXXXXXXXXRIVTVCLEGLENILKVGETDKNLGASGEGN 596 TSGGS +QIKYLV GCIK +IV V L GLENIL++GE + +G N Sbjct: 408 TSGGSAEQIKYLVELGCIKPLCDLLTVMDSKIVQVALNGLENILRLGEQEAKRNGTGI-N 466 Query: 597 VYAQMIDEAEGLEK 638 Y +I+EA GL+K Sbjct: 467 PYCALIEEAYGLDK 480 Score = 58.9 bits (141), Expect = 1e-08 Identities = 40/161 (24%), Positives = 73/161 (45%) Frame = +3 Query: 66 VIDAGVCPRLVELLLHPSPSVLIPALRTVGNIVTGDDSQTQCIIDHQALGCLLSLLTENH 245 VI AG P +ELL V A+ +GNI ++D L LL L ++ + Sbjct: 165 VIQAGAVPIFIELLSSEFEDVQEQAVWALGNIAGDSTMCRDYVLDCNILPPLLQLFSKQN 224 Query: 246 KKSIKKEACWTVSNITAGNKDQIQAVITAGIIFPLVHLLQTAEFDIKKEAAWAISNATSG 425 + ++ + A W +SN+ G + + + L LL ++ D+ +A WA+S S Sbjct: 225 RLTMTRNAVWALSNLCRGKSPPPEFAKVSPCLNVLSWLLFVSDTDVLADACWALS-YLSD 283 Query: 426 GSHDQIKYLVSEGCIKXXXXXXXXXXXRIVTVCLEGLENIL 548 G +D+I+ ++ G + ++V+ L + NI+ Sbjct: 284 GPNDKIQAVIDAGVCRRLVELLMHNDYKVVSPALRAVGNIV 324 Score = 45.4 bits (106), Expect = 1e-04 Identities = 24/109 (22%), Positives = 54/109 (49%), Gaps = 2/109 (1%) Frame = +3 Query: 93 LVELLLHPSPSVLIPALRTVGNIVTGDDSQT--QCIIDHQALGCLLSLLTENHKKSIKKE 266 ++E++ SP + A + +++ + + + I + + L +++ E Sbjct: 87 MIEMIFSKSPEQQLSATQKFRKLLSKEPNPPIDEVISTPGVVARFVEFLKRKENCTLQFE 146 Query: 267 ACWTVSNITAGNKDQIQAVITAGIIFPLVHLLQTAEFDIKKEAAWAISN 413 + W ++NI +GN Q + VI AG + + LL + D++++A WA+ N Sbjct: 147 SAWVLTNIASGNSLQTRIVIQAGAVPIFIELLSSEFEDVQEQAVWALGN 195 Score = 29.6 bits (65), Expect(2) = 4e-56 Identities = 12/18 (66%), Positives = 13/18 (72%) Frame = +2 Query: 2 LTXACWALSYLSEAPMXK 55 L ACWALSYLS+ P K Sbjct: 271 LADACWALSYLSDGPNDK 288
>IMA7_HUMAN (O60684) Importin alpha-7 subunit (Karyopherin alpha-6)| Length = 536 Score = 208 bits (530), Expect(2) = 4e-56 Identities = 115/194 (59%), Positives = 140/194 (72%) Frame = +3 Query: 57 IQSVIDAGVCPRLVELLLHPSPSVLIPALRTVGNIVTGDDSQTQCIIDHQALGCLLSLLT 236 IQ+VID+GVC RLVELL+H V PALR VGNIVTGDD QTQ I++ AL CLL LL+ Sbjct: 287 IQAVIDSGVCRRLVELLMHNDYKVASPALRAVGNIVTGDDIQTQVILNCSALPCLLHLLS 346 Query: 237 ENHKKSIKKEACWTVSNITAGNKDQIQAVITAGIIFPLVHLLQTAEFDIKKEAAWAISNA 416 + K+SI+KEACWT+SNITAGN+ QIQAVI A I L+ +LQ AEF +KEAAWAI+NA Sbjct: 347 -SPKESIRKEACWTISNITAGNRAQIQAVIDANIFPVLIEILQKAEFRTRKEAAWAITNA 405 Query: 417 TSGGSHDQIKYLVSEGCIKXXXXXXXXXXXRIVTVCLEGLENILKVGETDKNLGASGEGN 596 TSGG+ +QI+YLVS GCIK +IV V L GLENIL++GE + SG N Sbjct: 406 TSGGTPEQIRYLVSLGCIKPLCDLLTVMDSKIVQVALNGLENILRLGEQEGKRSGSGV-N 464 Query: 597 VYAQMIDEAEGLEK 638 Y +I+EA GL+K Sbjct: 465 PYCGLIEEAYGLDK 478 Score = 58.5 bits (140), Expect = 2e-08 Identities = 39/161 (24%), Positives = 76/161 (47%) Frame = +3 Query: 66 VIDAGVCPRLVELLLHPSPSVLIPALRTVGNIVTGDDSQTQCIIDHQALGCLLSLLTENH 245 VI+AG P +ELL V A+ +GNI +++ L LL+LLT++ Sbjct: 163 VIEAGAVPIFIELLNSDFEDVQEQAVWALGNIAGDSSVCRDYVLNCSILNPLLTLLTKST 222 Query: 246 KKSIKKEACWTVSNITAGNKDQIQAVITAGIIFPLVHLLQTAEFDIKKEAAWAISNATSG 425 + ++ + A W +SN+ G + + + L LL +++ D+ +A WA+S S Sbjct: 223 RLTMTRNAVWALSNLCRGKNPPPEFAKVSPCLPVLSRLLFSSDSDLLADACWALS-YLSD 281 Query: 426 GSHDQIKYLVSEGCIKXXXXXXXXXXXRIVTVCLEGLENIL 548 G +++I+ ++ G + ++ + L + NI+ Sbjct: 282 GPNEKIQAVIDSGVCRRLVELLMHNDYKVASPALRAVGNIV 322 Score = 29.6 bits (65), Expect(2) = 4e-56 Identities = 12/18 (66%), Positives = 13/18 (72%) Frame = +2 Query: 2 LTXACWALSYLSEAPMXK 55 L ACWALSYLS+ P K Sbjct: 269 LADACWALSYLSDGPNEK 286
>IMA5_HUMAN (O15131) Importin alpha-6 subunit (Karyopherin alpha-5 subunit)| Length = 536 Score = 207 bits (526), Expect(2) = 3e-55 Identities = 114/194 (58%), Positives = 140/194 (72%) Frame = +3 Query: 57 IQSVIDAGVCPRLVELLLHPSPSVLIPALRTVGNIVTGDDSQTQCIIDHQALGCLLSLLT 236 IQ+VID+GVC RLVELL+H V+ PALR VGNIVTGDD QTQ I++ AL CLL LL+ Sbjct: 287 IQAVIDSGVCRRLVELLMHNDYKVVSPALRAVGNIVTGDDIQTQVILNCSALPCLLHLLS 346 Query: 237 ENHKKSIKKEACWTVSNITAGNKDQIQAVITAGIIFPLVHLLQTAEFDIKKEAAWAISNA 416 + K+SI+KEACWTVSNITAGN+ QIQAVI A I L+ +LQ AEF +KEAAWAI+NA Sbjct: 347 -SPKESIRKEACWTVSNITAGNRAQIQAVIDANIFPVLIEILQKAEFRTRKEAAWAITNA 405 Query: 417 TSGGSHDQIKYLVSEGCIKXXXXXXXXXXXRIVTVCLEGLENILKVGETDKNLGASGEGN 596 TSGG+ +QI+YLV+ GCIK +IV V L GLENIL++GE + G N Sbjct: 406 TSGGTPEQIRYLVALGCIKPLCDLLTVMDSKIVQVALNGLENILRLGEQESKQNGIGI-N 464 Query: 597 VYAQMIDEAEGLEK 638 Y +I+EA GL+K Sbjct: 465 PYCALIEEAYGLDK 478 Score = 55.8 bits (133), Expect = 1e-07 Identities = 38/161 (23%), Positives = 74/161 (45%) Frame = +3 Query: 66 VIDAGVCPRLVELLLHPSPSVLIPALRTVGNIVTGDDSQTQCIIDHQALGCLLSLLTENH 245 VI+ G P ++LL V A+ +GNI + +++ + L LL LLT ++ Sbjct: 163 VIETGAVPIFIKLLNSEHEDVQEQAVWALGNIAGDNAECRDFVLNCEILPPLLELLTNSN 222 Query: 246 KKSIKKEACWTVSNITAGNKDQIQAVITAGIIFPLVHLLQTAEFDIKKEAAWAISNATSG 425 + + + A W +SN+ G + + L LL +++ D+ + WA+S S Sbjct: 223 RLTTTRNAVWALSNLCRGKNPPPNFSKVSPCLNVLSRLLFSSDPDVLADVCWALS-YLSD 281 Query: 426 GSHDQIKYLVSEGCIKXXXXXXXXXXXRIVTVCLEGLENIL 548 G +D+I+ ++ G + ++V+ L + NI+ Sbjct: 282 GPNDKIQAVIDSGVCRRLVELLMHNDYKVVSPALRAVGNIV 322 Score = 28.1 bits (61), Expect(2) = 3e-55 Identities = 11/18 (61%), Positives = 12/18 (66%) Frame = +2 Query: 2 LTXACWALSYLSEAPMXK 55 L CWALSYLS+ P K Sbjct: 269 LADVCWALSYLSDGPNDK 286
>IMA1_SCHPO (O14063) Importin alpha subunit (Karyopherin alpha subunit)| (Serine-rich RNA polymerase I suppressor protein) (Cell untimely torn protein 15) Length = 542 Score = 202 bits (513), Expect(2) = 8e-52 Identities = 110/195 (56%), Positives = 141/195 (72%), Gaps = 2/195 (1%) Frame = +3 Query: 57 IQSVIDAGVCPRLVELLLHPSPSVLIPALRTVGNIVTGDDSQTQCIIDHQALGCLLSLLT 236 IQ++IDAG+ RLVELL+HPS V PALR+VGNIVTGDD QTQ II+ AL LLSLL+ Sbjct: 283 IQAIIDAGIPRRLVELLMHPSAQVQTPALRSVGNIVTGDDVQTQVIINCGALSALLSLLS 342 Query: 237 ENHKKSIKKEACWTVSNITAGNKDQIQAVITAGIIFPLVHLLQTAEFDIKKEAAWAISNA 416 + + ++KEACWT+SNITAGN QIQ VI A II PL+HLL TA+F I+KEA WAISNA Sbjct: 343 -SPRDGVRKEACWTISNITAGNSSQIQYVIEANIIPPLIHLLTTADFKIQKEACWAISNA 401 Query: 417 TSGGSH--DQIKYLVSEGCIKXXXXXXXXXXXRIVTVCLEGLENILKVGETDKNLGASGE 590 TSGG+ DQI+YLV +G IK +I+ V L+G+ENIL+VGE D+ + Sbjct: 402 TSGGARRPDQIRYLVEQGAIKPLCNLLACQDNKIIQVALDGIENILRVGELDR-ANNPDK 460 Query: 591 GNVYAQMIDEAEGLE 635 N+YA +++A G++ Sbjct: 461 INLYAVYVEDAGGMD 475 Score = 68.9 bits (167), Expect = 1e-11 Identities = 35/124 (28%), Positives = 69/124 (55%), Gaps = 1/124 (0%) Frame = +3 Query: 57 IQSVIDAGVCPRLVELLLHPSPSVLIPALRTVGNIVTGDDSQTQCIIDHQALGCLLSLLT 236 IQ VIDAGV PR VE L H + + A + N+ +G +QT +++ A+ +SLL+ Sbjct: 114 IQKVIDAGVVPRFVEFLSHENNLLKFEASWALTNVASGSSNQTHVVVEANAVPVFVSLLS 173 Query: 237 ENHKKSIKKEACWTVSNITAGNKDQIQAVITAGIIFPLVHLLQT-AEFDIKKEAAWAISN 413 + ++ ++++A W + NI + V+ G++ PL++++++ + + + W +SN Sbjct: 174 SS-EQDVREQAVWALGNIAGDSPMCRDHVLQCGVLEPLLNIIESNRRLSMLRNSTWTLSN 232 Query: 414 ATSG 425 G Sbjct: 233 MCRG 236 Score = 33.9 bits (76), Expect = 0.42 Identities = 17/41 (41%), Positives = 24/41 (58%) Frame = +3 Query: 312 IQAVITAGIIFPLVHLLQTAEFDIKKEAAWAISNATSGGSH 434 IQ VI AG++ V L +K EA+WA++N SG S+ Sbjct: 114 IQKVIDAGVVPRFVEFLSHENNLLKFEASWALTNVASGSSN 154 Score = 21.9 bits (45), Expect(2) = 8e-52 Identities = 9/18 (50%), Positives = 11/18 (61%) Frame = +2 Query: 2 LTXACWALSYLSEAPMXK 55 L A WA+SYLS+ K Sbjct: 265 LVDALWAISYLSDGANEK 282
>IMA1_YEAST (Q02821) Importin alpha subunit (Karyopherin alpha subunit)| (Serine-rich RNA polymerase I suppressor protein) Length = 542 Score = 186 bits (471), Expect(2) = 7e-49 Identities = 111/197 (56%), Positives = 133/197 (67%), Gaps = 3/197 (1%) Frame = +3 Query: 57 IQSVIDAGVCPRLVELLLHPSPSVLIPALRTVGNIVTGDDSQTQCIIDHQALGCLLSLLT 236 IQ+VID + RLVELL H S V PALR VGNIVTG+D QTQ +I+ L L LL Sbjct: 292 IQAVIDVRIPKRLVELLSHESTLVQTPALRAVGNIVTGNDLQTQVVINAGVLPAL-RLLL 350 Query: 237 ENHKKSIKKEACWTVSNITAGNKDQIQAVITAGIIFPLVHLLQTAEFDIKKEAAWAISNA 416 + K++IKKEACWT+SNITAGN +QIQAVI A +I PLV LL+ AE+ KKEA WAISNA Sbjct: 351 SSPKENIKKEACWTISNITAGNTEQIQAVIDANLIPPLVKLLEVAEYKTKKEACWAISNA 410 Query: 417 TSGGSH--DQIKYLVSEGCIKXXXXXXXXXXXRIVTVCLEGLENILKVGETDKNLGASGE 590 +SGG D I+YLVS+GCIK RI+ V L+ LENILK+GE DK A G Sbjct: 411 SSGGLQRPDIIRYLVSQGCIKPLCDLLEIADNRIIEVTLDALENILKMGEADKE--ARGL 468 Query: 591 G-NVYAQMIDEAEGLEK 638 N A I++A G+EK Sbjct: 469 NINENADFIEKAGGMEK 485 Score = 63.5 bits (153), Expect = 5e-10 Identities = 37/130 (28%), Positives = 63/130 (48%), Gaps = 1/130 (0%) Frame = +3 Query: 39 RHQXTXIQSVIDAGVCPRLVELLLHPSPSVL-IPALRTVGNIVTGDDSQTQCIIDHQALG 215 R I VI AGV PRLVE + P +L + A + NI +G +QT+ ++D A+ Sbjct: 117 REHRPPIDVVIQAGVVPRLVEFMRENQPEMLQLEAAWALTNIASGTSAQTKVVVDADAVP 176 Query: 216 CLLSLLTENHKKSIKKEACWTVSNITAGNKDQIQAVITAGIIFPLVHLLQTAEFDIKKEA 395 + LL +K++A W + N+ + D V+ + P++ L + + + + A Sbjct: 177 LFIQLLYTG-SVEVKEQAIWALGNVAGDSTDYRDYVLQCNAMEPILGLFNSNKPSLIRTA 235 Query: 396 AWAISNATSG 425 W +SN G Sbjct: 236 TWTLSNLCRG 245 Score = 54.3 bits (129), Expect = 3e-07 Identities = 40/161 (24%), Positives = 69/161 (42%) Frame = +3 Query: 66 VIDAGVCPRLVELLLHPSPSVLIPALRTVGNIVTGDDSQTQCIIDHQALGCLLSLLTENH 245 V+DA P ++LL S V A+ +GN+ ++ A+ +L L N Sbjct: 169 VVDADAVPLFIQLLYTGSVEVKEQAIWALGNVAGDSTDYRDYVLQCNAMEPILGLFNSN- 227 Query: 246 KKSIKKEACWTVSNITAGNKDQIQAVITAGIIFPLVHLLQTAEFDIKKEAAWAISNATSG 425 K S+ + A WT+SN+ G K Q + + + L L+ + + + +A WAIS S Sbjct: 228 KPSLIRTATWTLSNLCRGKKPQPDWSVVSQALPTLAKLIYSMDTETLVDACWAIS-YLSD 286 Query: 426 GSHDQIKYLVSEGCIKXXXXXXXXXXXRIVTVCLEGLENIL 548 G + I+ ++ K + T L + NI+ Sbjct: 287 GPQEAIQAVIDVRIPKRLVELLSHESTLVQTPALRAVGNIV 327 Score = 30.4 bits (67), Expect = 4.6 Identities = 16/45 (35%), Positives = 28/45 (62%), Gaps = 1/45 (2%) Frame = +3 Query: 300 NKDQIQAVITAGIIFPLVHLLQTAEFD-IKKEAAWAISNATSGGS 431 ++ I VI AG++ LV ++ + + ++ EAAWA++N SG S Sbjct: 119 HRPPIDVVIQAGVVPRLVEFMRENQPEMLQLEAAWALTNIASGTS 163 Score = 28.1 bits (61), Expect(2) = 7e-49 Identities = 10/15 (66%), Positives = 12/15 (80%) Frame = +2 Query: 2 LTXACWALSYLSEAP 46 L ACWA+SYLS+ P Sbjct: 274 LVDACWAISYLSDGP 288
>IMA4_MOUSE (O35343) Importin alpha-4 subunit (Karyopherin alpha-4 subunit)| (Importin alpha Q1) Length = 521 Score = 155 bits (392), Expect(2) = 1e-37 Identities = 88/194 (45%), Positives = 115/194 (59%) Frame = +3 Query: 57 IQSVIDAGVCPRLVELLLHPSPSVLIPALRTVGNIVTGDDSQTQCIIDHQALGCLLSLLT 236 IQ VID+G+ P LV LL H V ALR VGNIVTG D QTQ +++ AL +LLT Sbjct: 277 IQMVIDSGIVPHLVPLLSHQEVKVQTAALRAVGNIVTGTDEQTQVVLNCDALSHFPALLT 336 Query: 237 ENHKKSIKKEACWTVSNITAGNKDQIQAVITAGIIFPLVHLLQTAEFDIKKEAAWAISNA 416 + K+ I KEA W +SNITAGN+ Q+QAVI A ++ ++HLL +F +KEAAWAISN Sbjct: 337 -HPKEKINKEAVWFLSNITAGNQQQVQAVIDANLVPMIIHLLDKGDFGTQKEAAWAISNL 395 Query: 417 TSGGSHDQIKYLVSEGCIKXXXXXXXXXXXRIVTVCLEGLENILKVGETDKNLGASGEGN 596 T G DQ+ YL+ + I ++V V L+GL NILK+ E + Sbjct: 396 TISGRKDQVAYLIQQNVIPPFCNLLTVKDAQVVQVVLDGLSNILKMAE--------DQAE 447 Query: 597 VYAQMIDEAEGLEK 638 A +I+E GLEK Sbjct: 448 TIANLIEECGGLEK 461 Score = 50.1 bits (118), Expect = 6e-06 Identities = 44/208 (21%), Positives = 79/208 (37%), Gaps = 44/208 (21%) Frame = +3 Query: 57 IQSVIDAGVCPRLVELLLHP-SPSVLIPALRTVGNIVTGDDSQTQCIIDHQALGCLLSLL 233 I +I +G+ P LV L +PS+ A + NI +G QTQ ++ A+ L LL Sbjct: 107 IDDLIKSGILPILVHCLERDDNPSLQFEAAWALTNIASGTSEQTQAVVQSNAVPLFLRLL 166 Query: 234 TENHKKSIKKEACWTVSNITAGNKDQIQAVITAGIIFPLVH------------------- 356 H +++ ++A W + NI VI+ G++ PL+ Sbjct: 167 HSPH-QNVCEQAVWALGNIIGDGPQCRDYVISLGVVKPLLSFISPSIPITFLRNVTWVMV 225 Query: 357 ------------------------LLQTAEFDIKKEAAWAISNATSGGSHDQIKYLVSEG 464 L+ + +I + WA+S T G ++QI+ ++ G Sbjct: 226 NLCRHKDPPPPMETIQEILPALCVLIHHTDVNILVDTVWALSYLTDAG-NEQIQMVIDSG 284 Query: 465 CIKXXXXXXXXXXXRIVTVCLEGLENIL 548 + ++ T L + NI+ Sbjct: 285 IVPHLVPLLSHQEVKVQTAALRAVGNIV 312 Score = 41.2 bits (95), Expect = 0.003 Identities = 37/124 (29%), Positives = 55/124 (44%), Gaps = 4/124 (3%) Frame = +3 Query: 66 VIDAGVCPRLVELLLHPSPSVLIPALRTVG----NIVTGDDSQTQCIIDHQALGCLLSLL 233 VI GV L+ + SPS+ I LR V N+ D + L L L+ Sbjct: 195 VISLGVVKPLLSFI---SPSIPITFLRNVTWVMVNLCRHKDPPPPMETIQEILPALCVLI 251 Query: 234 TENHKKSIKKEACWTVSNITAGNKDQIQAVITAGIIFPLVHLLQTAEFDIKKEAAWAISN 413 + +I + W +S +T +QIQ VI +GI+ LV LL E ++ A A+ N Sbjct: 252 -HHTDVNILVDTVWALSYLTDAGNEQIQMVIDSGIVPHLVPLLSHQEVKVQTAALRAVGN 310 Query: 414 ATSG 425 +G Sbjct: 311 IVTG 314 Score = 21.2 bits (43), Expect(2) = 1e-37 Identities = 8/14 (57%), Positives = 10/14 (71%) Frame = +2 Query: 2 LTXACWALSYLSEA 43 L WALSYL++A Sbjct: 259 LVDTVWALSYLTDA 272
>IMA4_HUMAN (O00629) Importin alpha-4 subunit (Karyopherin alpha-4 subunit)| (Qip1 protein) Length = 521 Score = 155 bits (391), Expect(2) = 1e-37 Identities = 88/194 (45%), Positives = 114/194 (58%) Frame = +3 Query: 57 IQSVIDAGVCPRLVELLLHPSPSVLIPALRTVGNIVTGDDSQTQCIIDHQALGCLLSLLT 236 IQ VID+G+ P LV LL H V ALR VGNIVTG D QTQ +++ AL +LLT Sbjct: 277 IQMVIDSGIVPHLVPLLSHQEVKVQTAALRAVGNIVTGTDEQTQVVLNCDALSHFPALLT 336 Query: 237 ENHKKSIKKEACWTVSNITAGNKDQIQAVITAGIIFPLVHLLQTAEFDIKKEAAWAISNA 416 + K+ I KEA W +SNITAGN+ Q+QAVI A ++ ++HLL +F +KEAAWAISN Sbjct: 337 -HPKEKINKEAVWFLSNITAGNQQQVQAVIDANLVPMIIHLLDKGDFGTQKEAAWAISNL 395 Query: 417 TSGGSHDQIKYLVSEGCIKXXXXXXXXXXXRIVTVCLEGLENILKVGETDKNLGASGEGN 596 T G DQ+ YL+ + I ++V V L+GL NILK+ E E Sbjct: 396 TISGRKDQVAYLIQQNVIPPFCNLLTVKDAQVVQVVLDGLSNILKMAE--------DEAE 447 Query: 597 VYAQMIDEAEGLEK 638 +I+E GLEK Sbjct: 448 TIGNLIEECGGLEK 461 Score = 50.1 bits (118), Expect = 6e-06 Identities = 44/208 (21%), Positives = 79/208 (37%), Gaps = 44/208 (21%) Frame = +3 Query: 57 IQSVIDAGVCPRLVELLLHP-SPSVLIPALRTVGNIVTGDDSQTQCIIDHQALGCLLSLL 233 I +I +G+ P LV L +PS+ A + NI +G QTQ ++ A+ L LL Sbjct: 107 IDDLIKSGILPILVHCLERDDNPSLQFEAAWALTNIASGTSEQTQAVVQSNAVPLFLRLL 166 Query: 234 TENHKKSIKKEACWTVSNITAGNKDQIQAVITAGIIFPLVH------------------- 356 H +++ ++A W + NI VI+ G++ PL+ Sbjct: 167 HSPH-QNVCEQAVWALGNIIGDGPQCRDYVISLGVVKPLLSFISPSIPITFLRNVTWVMV 225 Query: 357 ------------------------LLQTAEFDIKKEAAWAISNATSGGSHDQIKYLVSEG 464 L+ + +I + WA+S T G ++QI+ ++ G Sbjct: 226 NLCRHKDPPPPMETIQEILPALCVLIHHTDVNILVDTVWALSYLTDAG-NEQIQMVIDSG 284 Query: 465 CIKXXXXXXXXXXXRIVTVCLEGLENIL 548 + ++ T L + NI+ Sbjct: 285 IVPHLVPLLSHQEVKVQTAALRAVGNIV 312 Score = 41.2 bits (95), Expect = 0.003 Identities = 37/124 (29%), Positives = 55/124 (44%), Gaps = 4/124 (3%) Frame = +3 Query: 66 VIDAGVCPRLVELLLHPSPSVLIPALRTVG----NIVTGDDSQTQCIIDHQALGCLLSLL 233 VI GV L+ + SPS+ I LR V N+ D + L L L+ Sbjct: 195 VISLGVVKPLLSFI---SPSIPITFLRNVTWVMVNLCRHKDPPPPMETIQEILPALCVLI 251 Query: 234 TENHKKSIKKEACWTVSNITAGNKDQIQAVITAGIIFPLVHLLQTAEFDIKKEAAWAISN 413 + +I + W +S +T +QIQ VI +GI+ LV LL E ++ A A+ N Sbjct: 252 -HHTDVNILVDTVWALSYLTDAGNEQIQMVIDSGIVPHLVPLLSHQEVKVQTAALRAVGN 310 Query: 414 ATSG 425 +G Sbjct: 311 IVTG 314 Score = 21.2 bits (43), Expect(2) = 1e-37 Identities = 8/14 (57%), Positives = 10/14 (71%) Frame = +2 Query: 2 LTXACWALSYLSEA 43 L WALSYL++A Sbjct: 259 LVDTVWALSYLTDA 272
>IMA2_MOUSE (P52293) Importin alpha-2 subunit (Karyopherin alpha-2 subunit)| (SRP1-alpha) (RAG cohort protein 1) (Pendulin) (Pore targeting complex 58 kDa subunit) (PTAC58) (Importin alpha P1) Length = 529 Score = 150 bits (378), Expect(2) = 2e-37 Identities = 89/194 (45%), Positives = 119/194 (61%) Frame = +3 Query: 57 IQSVIDAGVCPRLVELLLHPSPSVLIPALRTVGNIVTGDDSQTQCIIDHQALGCLLSLLT 236 I+ V+ GV P+LV+LL ++ PALR +GNIVTG D QTQ +ID AL SLLT Sbjct: 286 IEMVVKKGVVPQLVKLLGATELPIVTPALRAIGNIVTGTDEQTQKVIDAGALAVFPSLLT 345 Query: 237 ENHKKSIKKEACWTVSNITAGNKDQIQAVITAGIIFPLVHLLQTAEFDIKKEAAWAISNA 416 N K +I+KEA WT+SNITAG +DQIQ V+ G++ LV +L A+F +KEAAWAI+N Sbjct: 346 -NPKTNIQKEATWTMSNITAGRQDQIQQVVNHGLVPFLVGVLSKADFKTQKEAAWAITNY 404 Query: 417 TSGGSHDQIKYLVSEGCIKXXXXXXXXXXXRIVTVCLEGLENILKVGETDKNLGASGEGN 596 TSGG+ +QI YLV G I+ +I+ V L+ + NI + E GE Sbjct: 405 TSGGTVEQIVYLVHCGIIEPLMNLLSAKDTKIIQVILDAISNIFQAAE------KLGETE 458 Query: 597 VYAQMIDEAEGLEK 638 + MI+E GL+K Sbjct: 459 KLSIMIEECGGLDK 472 Score = 59.3 bits (142), Expect = 9e-09 Identities = 45/168 (26%), Positives = 77/168 (45%), Gaps = 5/168 (2%) Frame = +3 Query: 60 QSVIDAGVCPRLVELLLHPSPSVLIPALRTVGNIVTGDDSQTQCIIDHQALGCLLSLLTE 239 ++V+D G P + LL P + A+ +GNI + +I H A+ LL+LL Sbjct: 156 KAVVDGGAIPAFISLLASPHAHISEQAVWALGNIAGDGSAFRDLVIKHGAIDPLLALLAV 215 Query: 240 NHKKSIK----KEACWTVSNITAGNKDQIQAVITAGIIFP-LVHLLQTAEFDIKKEAAWA 404 ++ + WT+SN+ NK+ + I P LV LL + ++ ++ WA Sbjct: 216 PDLSTLACGYLRNLTWTLSNL-CRNKNPAPPLDAVEQILPTLVRLLHHNDPEVLADSCWA 274 Query: 405 ISNATSGGSHDQIKYLVSEGCIKXXXXXXXXXXXRIVTVCLEGLENIL 548 IS T G +++I+ +V +G + IVT L + NI+ Sbjct: 275 ISYLTD-GPNERIEMVVKKGVVPQLVKLLGATELPIVTPALRAIGNIV 321 Score = 50.4 bits (119), Expect = 4e-06 Identities = 37/131 (28%), Positives = 57/131 (43%), Gaps = 6/131 (4%) Frame = +3 Query: 39 RHQXTXIQSVIDAGVCPRLVELLLHPSPS-VLIPALRTVGNIVTGDDSQTQCIIDHQALG 215 R + I ++I AG+ P+ V L S + + + NI +G QT+ ++D A+ Sbjct: 106 REKQPPIDNIIRAGLIPKFVSFLGKTDCSPIQFESAWALTNIASGTSEQTKAVVDGGAIP 165 Query: 216 CLLSLLTENHKKSIKKEACWTVSNITAGNKDQIQAVITAGIIFPLVHL-----LQTAEFD 380 +SLL H I ++A W + NI VI G I PL+ L L T Sbjct: 166 AFISLLASPH-AHISEQAVWALGNIAGDGSAFRDLVIKHGAIDPLLALLAVPDLSTLACG 224 Query: 381 IKKEAAWAISN 413 + W +SN Sbjct: 225 YLRNLTWTLSN 235 Score = 25.8 bits (55), Expect(2) = 2e-37 Identities = 8/15 (53%), Positives = 12/15 (80%) Frame = +2 Query: 2 LTXACWALSYLSEAP 46 L +CWA+SYL++ P Sbjct: 268 LADSCWAISYLTDGP 282
>IMA2_HUMAN (P52292) Importin alpha-2 subunit (Karyopherin alpha-2 subunit)| (SRP1-alpha) (RAG cohort protein 1) Length = 529 Score = 148 bits (373), Expect(2) = 9e-37 Identities = 87/194 (44%), Positives = 117/194 (60%) Frame = +3 Query: 57 IQSVIDAGVCPRLVELLLHPSPSVLIPALRTVGNIVTGDDSQTQCIIDHQALGCLLSLLT 236 I V+ GV P+LV+LL ++ PALR +GNIVTG D QTQ +ID AL SLLT Sbjct: 286 IGMVVKTGVVPQLVKLLGASELPIVTPALRAIGNIVTGTDEQTQVVIDAGALAVFPSLLT 345 Query: 237 ENHKKSIKKEACWTVSNITAGNKDQIQAVITAGIIFPLVHLLQTAEFDIKKEAAWAISNA 416 N K +I+KEA WT+SNITAG +DQIQ V+ G++ LV +L A+F +KEA WA++N Sbjct: 346 -NPKTNIQKEATWTMSNITAGRQDQIQQVVNHGLVPFLVSVLSKADFKTQKEAVWAVTNY 404 Query: 417 TSGGSHDQIKYLVSEGCIKXXXXXXXXXXXRIVTVCLEGLENILKVGETDKNLGASGEGN 596 TSGG+ +QI YLV G I+ +I+ V L+ + NI + E GE Sbjct: 405 TSGGTVEQIVYLVHCGIIEPLMNLLTAKDTKIILVILDAISNIFQAAE------KLGETE 458 Query: 597 VYAQMIDEAEGLEK 638 + MI+E GL+K Sbjct: 459 KLSIMIEECGGLDK 472 Score = 55.5 bits (132), Expect = 1e-07 Identities = 45/168 (26%), Positives = 73/168 (43%), Gaps = 5/168 (2%) Frame = +3 Query: 60 QSVIDAGVCPRLVELLLHPSPSVLIPALRTVGNIVTGDDSQTQCIIDHQALGCLLSLLTE 239 ++V+D G P + LL P + A+ +GNI +I + A+ LL+LL Sbjct: 156 KAVVDGGAIPAFISLLASPHAHISEQAVWALGNIAGDGSVFRDLVIKYGAVDPLLALLAV 215 Query: 240 NHKKSIK----KEACWTVSNITAGNKDQIQAVITAGIIFP-LVHLLQTAEFDIKKEAAWA 404 S+ + WT+SN+ NK+ + I P LV LL + ++ + WA Sbjct: 216 PDMSSLACGYLRNLTWTLSNL-CRNKNPAPPIDAVEQILPTLVRLLHHDDPEVLADTCWA 274 Query: 405 ISNATSGGSHDQIKYLVSEGCIKXXXXXXXXXXXRIVTVCLEGLENIL 548 IS T G +++I +V G + IVT L + NI+ Sbjct: 275 ISYLTD-GPNERIGMVVKTGVVPQLVKLLGASELPIVTPALRAIGNIV 321 Score = 50.1 bits (118), Expect = 6e-06 Identities = 35/131 (26%), Positives = 57/131 (43%), Gaps = 6/131 (4%) Frame = +3 Query: 39 RHQXTXIQSVIDAGVCPRLVELLLHPSPS-VLIPALRTVGNIVTGDDSQTQCIIDHQALG 215 R + I ++I AG+ P+ V L S + + + NI +G QT+ ++D A+ Sbjct: 106 REKQPPIDNIIRAGLIPKFVSFLGRTDCSPIQFESAWALTNIASGTSEQTKAVVDGGAIP 165 Query: 216 CLLSLLTENHKKSIKKEACWTVSNITAGNKDQIQAVITAGIIFPLVHLLQTAEFD----- 380 +SLL H I ++A W + NI VI G + PL+ LL + Sbjct: 166 AFISLLASPH-AHISEQAVWALGNIAGDGSVFRDLVIKYGAVDPLLALLAVPDMSSLACG 224 Query: 381 IKKEAAWAISN 413 + W +SN Sbjct: 225 YLRNLTWTLSN 235 Score = 25.4 bits (54), Expect(2) = 9e-37 Identities = 8/15 (53%), Positives = 11/15 (73%) Frame = +2 Query: 2 LTXACWALSYLSEAP 46 L CWA+SYL++ P Sbjct: 268 LADTCWAISYLTDGP 282
>IMA3_MOUSE (O35344) Importin alpha-3 subunit (Karyopherin alpha-3 subunit)| (Importin alpha Q2) Length = 521 Score = 152 bits (383), Expect = 1e-36 Identities = 89/194 (45%), Positives = 117/194 (60%) Frame = +3 Query: 57 IQSVIDAGVCPRLVELLLHPSPSVLIPALRTVGNIVTGDDSQTQCIIDHQALGCLLSLLT 236 IQ VID+GV P LV LL H V ALR VGNIVTG D QTQ +++ L +LL+ Sbjct: 277 IQMVIDSGVVPFLVPLLSHQEVKVQTAALRAVGNIVTGTDEQTQVVLNCDVLSHFPNLLS 336 Query: 237 ENHKKSIKKEACWTVSNITAGNKDQIQAVITAGIIFPLVHLLQTAEFDIKKEAAWAISNA 416 + K+ I KEA W +SNITAGN+ Q+QAVI AG+I ++H L +F +KEAAWAISN Sbjct: 337 -HPKEKINKEAVWFLSNITAGNQQQVQAVIDAGLIPMIIHQLAKGDFGTQKEAAWAISNL 395 Query: 417 TSGGSHDQIKYLVSEGCIKXXXXXXXXXXXRIVTVCLEGLENILKVGETDKNLGASGEGN 596 T G DQ++YLV + I ++V V L+GL+NIL + A E + Sbjct: 396 TISGRKDQVEYLVQQNVIPPFCNLLSVKDSQVVQVVLDGLKNIL--------IMAGDEAS 447 Query: 597 VYAQMIDEAEGLEK 638 A++I+E GLEK Sbjct: 448 TIAEIIEECGGLEK 461 Score = 52.0 bits (123), Expect = 1e-06 Identities = 39/164 (23%), Positives = 71/164 (43%), Gaps = 1/164 (0%) Frame = +3 Query: 60 QSVIDAGVCPRLVELLLHPSPSVLIPALRTVGNIVTGDDSQTQCIIDHQALGCLLSLLTE 239 Q+V+ + P + LL P +V A+ +GNI+ +I + LLS + Sbjct: 151 QAVVQSNAVPLFLRLLHSPHQNVCEQAVWALGNIIGDGPQCRDYVISLGVVKPLLSFINP 210 Query: 240 NHKKSIKKEACWTVSNITAGNKDQIQAVITAGIIFP-LVHLLQTAEFDIKKEAAWAISNA 416 + + + W + N+ NKD + T I P L L+ + +I + WA+S Sbjct: 211 SIPITFLRNVTWVIVNL-CRNKDPPPPMETVQEILPALCVLIYHTDINILVDTVWALSYL 269 Query: 417 TSGGSHDQIKYLVSEGCIKXXXXXXXXXXXRIVTVCLEGLENIL 548 T GG ++QI+ ++ G + ++ T L + NI+ Sbjct: 270 TDGG-NEQIQMVIDSGVVPFLVPLLSHQEVKVQTAALRAVGNIV 312 Score = 50.4 bits (119), Expect = 4e-06 Identities = 30/120 (25%), Positives = 60/120 (50%), Gaps = 1/120 (0%) Frame = +3 Query: 117 SPSVLIPALRTVGNIVTGD-DSQTQCIIDHQALGCLLSLLTENHKKSIKKEACWTVSNIT 293 +P V + A++ +++ D + +I L L+ L + S++ EA W ++NI Sbjct: 84 NPVVQLSAVQAARKLLSSDRNPPIDDLIKSGILPILVKCLERDDNPSLQFEAAWALTNIA 143 Query: 294 AGNKDQIQAVITAGIIFPLVHLLQTAEFDIKKEAAWAISNATSGGSHDQIKYLVSEGCIK 473 +G Q QAV+ + + + LL + ++ ++A WA+ N G + Y++S G +K Sbjct: 144 SGTSAQTQAVVQSNAVPLFLRLLHSPHQNVCEQAVWALGNIIGDGPQCR-DYVISLGVVK 202 Score = 41.2 bits (95), Expect = 0.003 Identities = 36/124 (29%), Positives = 55/124 (44%), Gaps = 4/124 (3%) Frame = +3 Query: 66 VIDAGVCPRLVELLLHPSPSVLIPALRTVG----NIVTGDDSQTQCIIDHQALGCLLSLL 233 VI GV L+ + +PS+ I LR V N+ D + L L L+ Sbjct: 195 VISLGVVKPLLSFI---NPSIPITFLRNVTWVIVNLCRNKDPPPPMETVQEILPALCVLI 251 Query: 234 TENHKKSIKKEACWTVSNITAGNKDQIQAVITAGIIFPLVHLLQTAEFDIKKEAAWAISN 413 +I + W +S +T G +QIQ VI +G++ LV LL E ++ A A+ N Sbjct: 252 YHTDI-NILVDTVWALSYLTDGGNEQIQMVIDSGVVPFLVPLLSHQEVKVQTAALRAVGN 310 Query: 414 ATSG 425 +G Sbjct: 311 IVTG 314
>IMA3_HUMAN (O00505) Importin alpha-3 subunit (Karyopherin alpha-3 subunit)| (SRP1-gamma) Length = 521 Score = 152 bits (383), Expect = 1e-36 Identities = 89/194 (45%), Positives = 117/194 (60%) Frame = +3 Query: 57 IQSVIDAGVCPRLVELLLHPSPSVLIPALRTVGNIVTGDDSQTQCIIDHQALGCLLSLLT 236 IQ VID+GV P LV LL H V ALR VGNIVTG D QTQ +++ L +LL+ Sbjct: 277 IQMVIDSGVVPFLVPLLSHQEVKVQTAALRAVGNIVTGTDEQTQVVLNCDVLSHFPNLLS 336 Query: 237 ENHKKSIKKEACWTVSNITAGNKDQIQAVITAGIIFPLVHLLQTAEFDIKKEAAWAISNA 416 + K+ I KEA W +SNITAGN+ Q+QAVI AG+I ++H L +F +KEAAWAISN Sbjct: 337 -HPKEKINKEAVWFLSNITAGNQQQVQAVIDAGLIPMIIHQLAKGDFGTQKEAAWAISNL 395 Query: 417 TSGGSHDQIKYLVSEGCIKXXXXXXXXXXXRIVTVCLEGLENILKVGETDKNLGASGEGN 596 T G DQ++YLV + I ++V V L+GL+NIL + A E + Sbjct: 396 TISGRKDQVEYLVQQNVIPPFCNLLSVKDSQVVQVVLDGLKNIL--------IMAGDEAS 447 Query: 597 VYAQMIDEAEGLEK 638 A++I+E GLEK Sbjct: 448 TIAEIIEECGGLEK 461 Score = 52.8 bits (125), Expect = 9e-07 Identities = 39/164 (23%), Positives = 72/164 (43%), Gaps = 1/164 (0%) Frame = +3 Query: 60 QSVIDAGVCPRLVELLLHPSPSVLIPALRTVGNIVTGDDSQTQCIIDHQALGCLLSLLTE 239 Q+V+ + P + LL P +V A+ +GNI+ +I + LLS ++ Sbjct: 151 QAVVQSNAVPLFLRLLRSPHQNVCEQAVWALGNIIGDGPQCRDYVISLGVVKPLLSFISP 210 Query: 240 NHKKSIKKEACWTVSNITAGNKDQIQAVITAGIIFP-LVHLLQTAEFDIKKEAAWAISNA 416 + + + W + N+ NKD + T I P L L+ + +I + WA+S Sbjct: 211 SIPITFLRNVTWVIVNL-CRNKDPPPPMETVQEILPALCVLIYHTDINILVDTVWALSYL 269 Query: 417 TSGGSHDQIKYLVSEGCIKXXXXXXXXXXXRIVTVCLEGLENIL 548 T GG ++QI+ ++ G + ++ T L + NI+ Sbjct: 270 TDGG-NEQIQMVIDSGVVPFLVPLLSHQEVKVQTAALRAVGNIV 312 Score = 50.8 bits (120), Expect = 3e-06 Identities = 30/120 (25%), Positives = 61/120 (50%), Gaps = 1/120 (0%) Frame = +3 Query: 117 SPSVLIPALRTVGNIVTGD-DSQTQCIIDHQALGCLLSLLTENHKKSIKKEACWTVSNIT 293 +P V + A++ +++ D + +I L L+ L + S++ EA W ++NI Sbjct: 84 NPVVQLSAVQAARKLLSSDRNPPIDDLIKSGILPILVKCLERDDNPSLQFEAAWALTNIA 143 Query: 294 AGNKDQIQAVITAGIIFPLVHLLQTAEFDIKKEAAWAISNATSGGSHDQIKYLVSEGCIK 473 +G Q QAV+ + + + LL++ ++ ++A WA+ N G + Y++S G +K Sbjct: 144 SGTSAQTQAVVQSNAVPLFLRLLRSPHQNVCEQAVWALGNIIGDGPQCR-DYVISLGVVK 202 Score = 42.4 bits (98), Expect = 0.001 Identities = 37/124 (29%), Positives = 55/124 (44%), Gaps = 4/124 (3%) Frame = +3 Query: 66 VIDAGVCPRLVELLLHPSPSVLIPALRTVG----NIVTGDDSQTQCIIDHQALGCLLSLL 233 VI GV L+ + SPS+ I LR V N+ D + L L L+ Sbjct: 195 VISLGVVKPLLSFI---SPSIPITFLRNVTWVIVNLCRNKDPPPPMETVQEILPALCVLI 251 Query: 234 TENHKKSIKKEACWTVSNITAGNKDQIQAVITAGIIFPLVHLLQTAEFDIKKEAAWAISN 413 +I + W +S +T G +QIQ VI +G++ LV LL E ++ A A+ N Sbjct: 252 YHTDI-NILVDTVWALSYLTDGGNEQIQMVIDSGVVPFLVPLLSHQEVKVQTAALRAVGN 310 Query: 414 ATSG 425 +G Sbjct: 311 IVTG 314
>IMA_DROME (P52295) Importin alpha subunit (Karyopherin alpha subunit)| (Pendulin) Length = 522 Score = 140 bits (353), Expect(2) = 5e-34 Identities = 87/197 (44%), Positives = 120/197 (60%), Gaps = 1/197 (0%) Frame = +3 Query: 51 TXIQSVIDAGVCPRLVELLLHPSPSVLIPALRTVGNIVTGDDSQTQCIIDHQALGCLLSL 230 T IQ+V+D+ PRLV+LL PS+++PALR+VGNIVTG D QT +I L L L Sbjct: 273 TKIQAVVDSDAVPRLVKLLQMDEPSIIVPALRSVGNIVTGTDQQTDVVIASGGLP-RLGL 331 Query: 231 LTENHKKSIKKEACWTVSNITAGNKDQIQAVITAGIIFPLVHLLQTAEFDIKKEAAWAIS 410 L +++K +I KEA WTVSNITAGN+ QIQAVI AGI L +L+ +F +KEAAWA++ Sbjct: 332 LLQHNKSNIVKEAAWTVSNITAGNQKQIQAVIQAGIFQQLRTVLEKGDFKAQKEAAWAVT 391 Query: 411 NATSGGSHDQIKYLVSE-GCIKXXXXXXXXXXXRIVTVCLEGLENILKVGETDKNLGASG 587 N T+ G+ +QI L+ + +K R + V GL N+ + E LG G Sbjct: 392 NTTTSGTPEQIVDLIEKYKILKPFIDLLDTKDPRTIKVVQTGLSNLFALAE---KLG--G 446 Query: 588 EGNVYAQMIDEAEGLEK 638 N+ M++E GL+K Sbjct: 447 TENL-CLMVEEMGGLDK 462 Score = 48.1 bits (113), Expect = 2e-05 Identities = 22/80 (27%), Positives = 40/80 (50%) Frame = +3 Query: 192 IIDHQALGCLLSLLTENHKKSIKKEACWTVSNITAGNKDQIQAVITAGIIFPLVHLLQTA 371 +I H + + L + ++ EA W ++NI +G DQ + VI + V LLQ+ Sbjct: 108 MIGHGIVPICIRFLQNTNNSMLQFEAAWALTNIASGTSDQTRCVIEHNAVPHFVALLQSK 167 Query: 372 EFDIKKEAAWAISNATSGGS 431 ++ ++A WA+ N G+ Sbjct: 168 SMNLAEQAVWALGNIAGDGA 187 Score = 47.4 bits (111), Expect = 4e-05 Identities = 35/145 (24%), Positives = 66/145 (45%), Gaps = 6/145 (4%) Frame = +3 Query: 39 RHQXTXIQSVIDAGVCPRLVELLLHPSPSVL-IPALRTVGNIVTGDDSQTQCIIDHQALG 215 R + I +I G+ P + L + + S+L A + NI +G QT+C+I+H A+ Sbjct: 99 RERNPPIDLMIGHGIVPICIRFLQNTNNSMLQFEAAWALTNIASGTSDQTRCVIEHNAVP 158 Query: 216 CLLSLLTENHKKSIKKEACWTVSNITAGNKDQIQAVITAGIIFPLVHLLQT-AEFDIKKE 392 ++LL ++ ++ ++A W + NI VI +I ++ L+ + Sbjct: 159 HFVALL-QSKSMNLAEQAVWALGNIAGDGAAARDIVIHHNVIDGILPLINNETPLSFLRN 217 Query: 393 AAWAISNATSGGS----HDQIKYLV 455 W +SN + DQ+K L+ Sbjct: 218 IVWLMSNLCRNKNPSPPFDQVKRLL 242 Score = 38.1 bits (87), Expect = 0.022 Identities = 24/82 (29%), Positives = 42/82 (51%) Frame = +3 Query: 219 LLSLLTENHKKSIKKEACWTVSNITAGNKDQIQAVITAGIIFPLVHLLQTAEFDIKKEAA 398 +LS L + + +ACW +S +T + +IQAV+ + + LV LLQ E I A Sbjct: 244 VLSQLLLSQDIQVLADACWALSYVTDDDNTKIQAVVDSDAVPRLVKLLQMDEPSIIVPAL 303 Query: 399 WAISNATSGGSHDQIKYLVSEG 464 ++ N + G+ Q +++ G Sbjct: 304 RSVGNIVT-GTDQQTDVVIASG 324 Score = 23.9 bits (50), Expect(2) = 5e-34 Identities = 8/13 (61%), Positives = 11/13 (84%) Frame = +2 Query: 2 LTXACWALSYLSE 40 L ACWALSY+++ Sbjct: 257 LADACWALSYVTD 269
>IMA2_XENLA (P52171) Importin alpha-2 subunit (Karyopherin alpha-2 subunit)| Length = 522 Score = 140 bits (352), Expect(2) = 1e-33 Identities = 80/194 (41%), Positives = 110/194 (56%) Frame = +3 Query: 57 IQSVIDAGVCPRLVELLLHPSPSVLIPALRTVGNIVTGDDSQTQCIIDHQALGCLLSLLT 236 I V+ G+ RL++L+ P S+L P+LRTVGNIVTG D QTQ ID L L LL Sbjct: 278 IDVVVKTGLVERLIQLMYSPELSILTPSLRTVGNIVTGTDKQTQAAIDAGVLSVLPQLL- 336 Query: 237 ENHKKSIKKEACWTVSNITAGNKDQIQAVITAGIIFPLVHLLQTAEFDIKKEAAWAISNA 416 + K SI+KEA W +SNI AG QIQ +IT G++ PLV LL+ +F +KEA WA++N Sbjct: 337 RHQKPSIQKEAAWALSNIAAGPAPQIQQMITCGLLSPLVDLLKKGDFKAQKEAVWAVTNY 396 Query: 417 TSGGSHDQIKYLVSEGCIKXXXXXXXXXXXRIVTVCLEGLENILKVGETDKNLGASGEGN 596 TSGG+ +Q+ LV G ++ + + V L+ + NI E GE Sbjct: 397 TSGGTVEQVVQLVQCGVLEPLLNLLTIKDSKTILVILDAISNIFLAAE------KLGEQE 450 Query: 597 VYAQMIDEAEGLEK 638 +++E GLEK Sbjct: 451 KLCLLVEELGGLEK 464 Score = 58.2 bits (139), Expect = 2e-08 Identities = 54/225 (24%), Positives = 91/225 (40%), Gaps = 44/225 (19%) Frame = +3 Query: 57 IQSVIDAGVCPRLVELL-LHPSPSVLIPALRTVGNIVTGDDSQTQCIIDHQALGCLLSLL 233 + +I+AG+ P+LVE L H + ++ A + NI +G QT+ ++D A+ +SL+ Sbjct: 108 LNDIIEAGLIPKLVEFLSYHNNSTLQFEAAWALTNIASGTSDQTKSVVDGGAIPAFISLI 167 Query: 234 TENHKKSIKKEACWTVSNITAGNKDQIQAVITAGIIFPLV-------------------- 353 + H I ++A W + NI A+I+ +I PL+ Sbjct: 168 SSPH-LHISEQAVWALGNIAGDGPLYRDALISCNVIPPLLTLVNPQTPLGYLRNITWTLS 226 Query: 354 -----------------------HLLQTAEFDIKKEAAWAISNATSGGSHDQIKYLVSEG 464 L+ + DI + WA+S T GS+D+I +V G Sbjct: 227 NLCRNKNPYPPMSAVLQILPVLTQLMLHEDKDILSDTCWAMSYLTD-GSNDRIDVVVKTG 285 Query: 465 CIKXXXXXXXXXXXRIVTVCLEGLENILKVGETDKNLGASGEGNV 599 ++ I+T L + NI V TDK A+ + V Sbjct: 286 LVERLIQLMYSPELSILTPSLRTVGNI--VTGTDKQTQAAIDAGV 328 Score = 23.1 bits (48), Expect(2) = 1e-33 Identities = 7/13 (53%), Positives = 11/13 (84%) Frame = +2 Query: 2 LTXACWALSYLSE 40 L+ CWA+SYL++ Sbjct: 260 LSDTCWAMSYLTD 272
>IMA1_XENLA (P52170) Importin alpha-1 subunit (Karyopherin alpha-1 subunit)| Length = 521 Score = 140 bits (352), Expect(2) = 1e-33 Identities = 79/194 (40%), Positives = 109/194 (56%) Frame = +3 Query: 57 IQSVIDAGVCPRLVELLLHPSPSVLIPALRTVGNIVTGDDSQTQCIIDHQALGCLLSLLT 236 I V+ G+ RL++L+ P S++ P+LRTVGNIVTG D QTQ ID L L LL Sbjct: 278 IDVVVKTGIVDRLIQLMYSPELSIVTPSLRTVGNIVTGTDKQTQAAIDAGVLSVLPQLL- 336 Query: 237 ENHKKSIKKEACWTVSNITAGNKDQIQAVITAGIIFPLVHLLQTAEFDIKKEAAWAISNA 416 + K SI+KEA W +SNI AG QIQ +IT G++ PLV LL +F +KEA WA++N Sbjct: 337 RHQKPSIQKEAAWAISNIAAGPAPQIQQMITCGLLSPLVDLLNKGDFKAQKEAVWAVTNY 396 Query: 417 TSGGSHDQIKYLVSEGCIKXXXXXXXXXXXRIVTVCLEGLENILKVGETDKNLGASGEGN 596 TSGG+ +Q+ LV G ++ + + V L+ + NI E GE Sbjct: 397 TSGGTVEQVVQLVQCGVLEPLLNLLTIKDSKTILVILDAISNIFLAAE------KLGEQE 450 Query: 597 VYAQMIDEAEGLEK 638 +++E GLEK Sbjct: 451 KLCLLVEELGGLEK 464 Score = 59.3 bits (142), Expect = 9e-09 Identities = 56/231 (24%), Positives = 91/231 (39%), Gaps = 44/231 (19%) Frame = +3 Query: 39 RHQXTXIQSVIDAGVCPRLVELL-LHPSPSVLIPALRTVGNIVTGDDSQTQCIIDHQALG 215 R + + +I+AG+ P+LVE L H + ++ A + NI +G QT+ ++D A+ Sbjct: 102 RERNPPLNDIIEAGLIPKLVEFLSRHDNSTLQFEAAWALTNIASGTSDQTKSVVDGGAIP 161 Query: 216 CLLSLLTENHKKSIKKEACWTVSNITAGNKDQIQAVITAGIIFPLV-------------- 353 +SL++ H I ++A W + NI A+I +I PL+ Sbjct: 162 AFISLISSPH-LHISEQAVWALGNIAGDGPLYRDALINCNVIPPLLALVNPQTPLGYLRN 220 Query: 354 -----------------------------HLLQTAEFDIKKEAAWAISNATSGGSHDQIK 446 L+ + DI + WA+S T GS+D+I Sbjct: 221 ITWMLSNLCRNKNPYPPMSAVLQILPVLTQLMHHDDKDILSDTCWAMSYLTD-GSNDRID 279 Query: 447 YLVSEGCIKXXXXXXXXXXXRIVTVCLEGLENILKVGETDKNLGASGEGNV 599 +V G + IVT L + NI V TDK A+ + V Sbjct: 280 VVVKTGIVDRLIQLMYSPELSIVTPSLRTVGNI--VTGTDKQTQAAIDAGV 328 Score = 23.1 bits (48), Expect(2) = 1e-33 Identities = 7/13 (53%), Positives = 11/13 (84%) Frame = +2 Query: 2 LTXACWALSYLSE 40 L+ CWA+SYL++ Sbjct: 260 LSDTCWAMSYLTD 272
>IMA3_CAEEL (Q19969) Importin alpha-3 subunit (Karyopherin alpha-3 subunit)| Length = 514 Score = 137 bits (344), Expect = 4e-32 Identities = 83/195 (42%), Positives = 113/195 (57%), Gaps = 1/195 (0%) Frame = +3 Query: 57 IQSVIDAGVCPRLVELLLHPSPSVLIPALRTVGNIVTGDDSQTQCIIDHQALGCLLSLLT 236 IQ VI+A V LV LL H V ALR VGNIVTG D QTQ ++D L + LL Sbjct: 270 IQMVIEAQVVTHLVPLLGHVDVKVQTAALRAVGNIVTGTDEQTQLVLDSGVLRFMPGLLA 329 Query: 237 ENHKKSIKKEACWTVSNITAGNKDQIQAVITAGIIFPLVHLLQTAEFDIKKEAAWAISNA 416 ++K+ I KEA W VSNITAGN+ Q+Q V AGI+ ++HLL +F +KEAAWAISN Sbjct: 330 -HYKEKINKEAVWFVSNITAGNQQQVQDVFDAGIMPMIIHLLDRGDFPTQKEAAWAISNV 388 Query: 417 TSGGSHDQIKYLVSEGCIKXXXXXXXXXXXRIVTVCLEGLENILKV-GETDKNLGASGEG 593 T G +Q++ +V G ++ +I+ V L+G+ NILK+ GE + + + Sbjct: 389 TISGRPNQVEQMVKLGVLRPFCAMLSCTDSQIIQVVLDGINNILKMAGEAAEQVTSE--- 445 Query: 594 NVYAQMIDEAEGLEK 638 I+E GL+K Sbjct: 446 ------IEECGGLDK 454 Score = 48.1 bits (113), Expect = 2e-05 Identities = 19/61 (31%), Positives = 35/61 (57%) Frame = +3 Query: 252 SIKKEACWTVSNITAGNKDQIQAVITAGIIFPLVHLLQTAEFDIKKEAAWAISNATSGGS 431 +++ EA W ++NI +G +Q QAV+ AG + + LL ++ +++ WA+ N G Sbjct: 123 NLQFEAAWALTNIASGTSEQTQAVVNAGAVPLFLQLLSCGNLNVCEQSVWALGNIIGDGP 182 Query: 432 H 434 H Sbjct: 183 H 183 Score = 42.4 bits (98), Expect = 0.001 Identities = 33/132 (25%), Positives = 63/132 (47%), Gaps = 5/132 (3%) Frame = +3 Query: 93 LVELLLHPSPSVLIPALRTVGNIVTG-----DDSQTQCIIDHQALGCLLSLLTENHKKSI 257 L LL +P + I LR V ++ D + + ++ + + LSLL + +I Sbjct: 194 LQPLLQFINPEIPIGFLRNVTWVIVNLCRCKDPAPSPAVV--RTILPALSLLIHHQDTNI 251 Query: 258 KKEACWTVSNITAGNKDQIQAVITAGIIFPLVHLLQTAEFDIKKEAAWAISNATSGGSHD 437 + W +S +T G + IQ VI A ++ LV LL + ++ A A+ N + G+ + Sbjct: 252 LIDTVWALSYLTDGGNEHIQMVIEAQVVTHLVPLLGHVDVKVQTAALRAVGNIVT-GTDE 310 Query: 438 QIKYLVSEGCIK 473 Q + ++ G ++ Sbjct: 311 QTQLVLDSGVLR 322 Score = 34.7 bits (78), Expect = 0.25 Identities = 19/53 (35%), Positives = 34/53 (64%) Frame = +3 Query: 312 IQAVITAGIIFPLVHLLQTAEFDIKKEAAWAISNATSGGSHDQIKYLVSEGCI 470 I +I +GI+ LV L + + +++ EAAWA++N SG S +Q + +V+ G + Sbjct: 101 IDDLIGSGILPVLVQCLSSTDPNLQFEAAWALTNIASGTS-EQTQAVVNAGAV 152
>IMA2_CAEEL (P91276) Importin alpha-2 subunit (Karyopherin alpha-2 subunit)| Length = 531 Score = 104 bits (260), Expect(2) = 8e-24 Identities = 52/138 (37%), Positives = 88/138 (63%) Frame = +3 Query: 57 IQSVIDAGVCPRLVELLLHPSPSVLIPALRTVGNIVTGDDSQTQCIIDHQALGCLLSLLT 236 I+ ++GV P +V + +++ PALRT+GN+ TG+DS TQ +ID +L +L L+ Sbjct: 296 IELARESGVLPHVVAFFKE-AENLVAPALRTLGNVATGNDSLTQAVIDLGSLDEILPLME 354 Query: 237 ENHKKSIKKEACWTVSNITAGNKDQIQAVITAGIIFPLVHLLQTAEFDIKKEAAWAISNA 416 + SI KE CW VSNI AG + QIQAV+ A ++ L+++L++ + + EA+WA+SN Sbjct: 355 KTRSSSIVKECCWLVSNIIAGTQKQIQAVLDANLLPVLINVLKSGDHKCQFEASWALSNL 414 Query: 417 TSGGSHDQIKYLVSEGCI 470 GG++ Q+ ++ + + Sbjct: 415 AQGGTNRQVVAMLEDNVV 432 Score = 50.4 bits (119), Expect = 4e-06 Identities = 23/69 (33%), Positives = 39/69 (56%) Frame = +3 Query: 225 SLLTENHKKSIKKEACWTVSNITAGNKDQIQAVITAGIIFPLVHLLQTAEFDIKKEAAWA 404 +L EN + ++ EA W ++NI +G+ +Q A + AG+ PL+HL I ++A WA Sbjct: 140 ALSVENER--VQYEAAWALTNIVSGSTEQTIAAVEAGVTIPLIHLSVHQSAQISEQALWA 197 Query: 405 ISNATSGGS 431 ++N S Sbjct: 198 VANIAGDSS 206 Score = 40.4 bits (93), Expect = 0.004 Identities = 33/122 (27%), Positives = 53/122 (43%), Gaps = 3/122 (2%) Frame = +3 Query: 57 IQSVIDAGVCPRLVELLLHPSPSVLIPALRTVGNIVTGDDSQTQCIIDHQALGCLLSLLT 236 I VI G+ LV+ L + V A + NIV+G QT ++ L+ L + Sbjct: 125 IDEVIHCGLLQALVQALSVENERVQYEAAWALTNIVSGSTEQTIAAVEAGVTIPLIHL-S 183 Query: 237 ENHKKSIKKEACWTVSNITAGNKDQIQAVITAGIIFPLVHLLQTAE---FDIKKEAAWAI 407 + I ++A W V+NI + VI + L+HL++ + + AWA Sbjct: 184 VHQSAQISEQALWAVANIAGDSSQLRDYVIKCHGVEALMHLMEKVDQLGDSHVRTIAWAF 243 Query: 408 SN 413 SN Sbjct: 244 SN 245 Score = 35.8 bits (81), Expect = 0.11 Identities = 37/166 (22%), Positives = 64/166 (38%), Gaps = 45/166 (27%) Frame = +3 Query: 63 SVIDAGVCPRLVELLLHPSPSVLIPALRTVGNIVTGDDSQTQCII--------------- 197 + ++AGV L+ L +H S + AL V NI GD SQ + + Sbjct: 169 AAVEAGVTIPLIHLSVHQSAQISEQALWAVANIA-GDSSQLRDYVIKCHGVEALMHLMEK 227 Query: 198 ------------------------DHQALGCLLSL------LTENHKKSIKKEACWTVSN 287 H L L L L ++ + ++++ACW VS Sbjct: 228 VDQLGDSHVRTIAWAFSNMCRHKNPHAPLEVLRVLSKGLVKLVQHTDRQVRQDACWAVSY 287 Query: 288 ITAGNKDQIQAVITAGIIFPLVHLLQTAEFDIKKEAAWAISNATSG 425 +T G +QI+ +G++ +V + AE ++ A + N +G Sbjct: 288 LTDGPDEQIELARESGVLPHVVAFFKEAE-NLVAPALRTLGNVATG 332 Score = 32.3 bits (72), Expect = 1.2 Identities = 16/44 (36%), Positives = 23/44 (52%) Frame = +3 Query: 312 IQAVITAGIIFPLVHLLQTAEFDIKKEAAWAISNATSGGSHDQI 443 I VI G++ LV L ++ EAAWA++N SG + I Sbjct: 125 IDEVIHCGLLQALVQALSVENERVQYEAAWALTNIVSGSTEQTI 168 Score = 25.4 bits (54), Expect(2) = 8e-24 Identities = 8/12 (66%), Positives = 11/12 (91%) Frame = +2 Query: 11 ACWALSYLSEAP 46 ACWA+SYL++ P Sbjct: 281 ACWAVSYLTDGP 292
>IMA2_ORYSA (Q9FYP9) Importin alpha-2 subunit| Length = 528 Score = 58.9 bits (141), Expect = 1e-08 Identities = 31/102 (30%), Positives = 58/102 (56%), Gaps = 6/102 (5%) Frame = +3 Query: 126 VLIPALRTVGNIVTGDDSQTQCIID------HQALGCLLSLLTENHKKSIKKEACWTVSN 287 +LIP LR +GN++ DD ++ QAL L+ L +++ ++KE+ W +SN Sbjct: 322 LLIPVLRGLGNLIAADDYMVDSVLTVGHNIIDQALSGLIKCLKSDNRV-LRKESSWALSN 380 Query: 288 ITAGNKDQIQAVITAGIIFPLVHLLQTAEFDIKKEAAWAISN 413 I AG+ + + + + L+ L+ + +FDI++EAA+ + N Sbjct: 381 IAAGSFEHKKLIFASEATPVLIRLVTSMQFDIRREAAYTLGN 422 Score = 36.2 bits (82), Expect = 0.085 Identities = 20/96 (20%), Positives = 45/96 (46%) Frame = +3 Query: 264 EACWTVSNITAGNKDQIQAVITAGIIFPLVHLLQTAEFDIKKEAAWAISNATSGGSHDQI 443 EA W ++NI AG ++ ++++ A + + HL + + + ++ AWAI N G+ + Sbjct: 155 EAAWCLTNIAAGEPEETKSLLPA-LPLLIAHLGEKSSTLVAEQCAWAIGNVAGEGA-ELR 212 Query: 444 KYLVSEGCIKXXXXXXXXXXXRIVTVCLEGLENILK 551 L+++G ++ + N++K Sbjct: 213 STLLAQGALRPLTRLMFSSKGSTARTAAWAMSNLIK 248 Score = 30.0 bits (66), Expect = 6.1 Identities = 20/88 (22%), Positives = 42/88 (47%), Gaps = 2/88 (2%) Frame = +3 Query: 150 VGNIVTGDDSQTQCIIDHQALGCLLSLLTENHKKSIKKEACWTVSNITAG--NKDQIQAV 323 +GN V G+ ++ + + Q L+ L + K S + A W +SN+ G K + + Sbjct: 201 IGN-VAGEGAELRSTLLAQGALRPLTRLMFSSKGSTARTAAWAMSNLIKGPDPKAANELI 259 Query: 324 ITAGIIFPLVHLLQTAEFDIKKEAAWAI 407 G++ ++ L+ + ++ E AW + Sbjct: 260 TIDGVLNAIIASLEKEDEELATEVAWVV 287
>IMA1_CAEEL (Q22560) Importin alpha-1 subunit (Karyopherin alpha-1 subunit)| Length = 524 Score = 52.8 bits (125), Expect = 9e-07 Identities = 32/163 (19%), Positives = 76/163 (46%) Frame = +3 Query: 72 DAGVCPRLVELLLHPSPSVLIPALRTVGNIVTGDDSQTQCIIDHQALGCLLSLLTENHKK 251 D +C +LV L + + + +I+ T+ +ID L L + ++ Sbjct: 279 DLKLCSKLVANLRNDKGNARPKVKAGINSIIQATGYFTEEMIDAGLLEVLKGFVNVSY-- 336 Query: 252 SIKKEACWTVSNITAGNKDQIQAVITAGIIFPLVHLLQTAEFDIKKEAAWAISNATSGGS 431 + +E C+ +SNI + I +I++G++ + +++ +E+ ++EAA+ I + + + Sbjct: 337 -MSQEVCFIISNICVEGEQTIDKLISSGVLREVARVMEASEYRSRREAAFVICHCCASAN 395 Query: 432 HDQIKYLVSEGCIKXXXXXXXXXXXRIVTVCLEGLENILKVGE 560 ++Y+V G + +V+ L+ + +L+ GE Sbjct: 396 QKHLEYVVELGMLSAFTDLLTCMDVSLVSYILDAIYLLLQFGE 438
>CTNB_TRIGR (P35223) Beta-catenin| Length = 820 Score = 47.4 bits (111), Expect = 4e-05 Identities = 39/174 (22%), Positives = 76/174 (43%), Gaps = 3/174 (1%) Frame = +3 Query: 33 SLRHQXTXIQSVIDAGVCPRLVELLLHPSPSVLIPALRTVGNIVTGDDSQTQCIIDHQAL 212 +L H + + +G P L++LL P SVL A+ T+ N++ + + L Sbjct: 236 NLSHHRAGLLQIFKSGGIPALIKLLSSPVESVLFYAITTLHNLLLHQEGSKMAVRLAGGL 295 Query: 213 GCLLSLLTENHKKSIKKEA-CWTVSNITAGNKDQIQAVITAGIIFPLVHLLQTAEFDIKK 389 +++LL+ N+ K + C + + GN++ ++ +G LVH+++T +++ Sbjct: 296 QKMVALLSRNNPKFLAITTDCLQI--LAYGNQESKLIILASGGPAALVHIMRTYDYE--- 350 Query: 390 EAAWAISNATSGGS--HDQIKYLVSEGCIKXXXXXXXXXXXRIVTVCLEGLENI 545 + W S S H+ +V G + R+V CL L N+ Sbjct: 351 KLLWTTSRVLKVLSVCHNNKPAIVEAGGMSALGLHLGHHSNRLVQNCLWTLRNL 404
>SPAG6_MOUSE (Q9JLI7) Sperm-associated antigen 6 (PF16 protein homolog) (Axoneme| central apparatus protein) Length = 507 Score = 45.4 bits (106), Expect = 1e-04 Identities = 43/164 (26%), Positives = 69/164 (42%) Frame = +3 Query: 60 QSVIDAGVCPRLVELLLHPSPSVLIPALRTVGNIVTGDDSQTQCIIDHQALGCLLSLLTE 239 ++V+ + P+LV L + A + + Q I+D AL L+ L E Sbjct: 77 EAVVKGDILPQLVYSLAEQNRFYKKAAAFVLRAVGKHSPQLAQAIVDCGALDTLVICL-E 135 Query: 240 NHKKSIKKEACWTVSNITAGNKDQIQAVITAGIIFPLVHLLQTAEFDIKKEAAWAISNAT 419 + +K+ A W + I N + QAV+ AG I LV +Q E +K+ AA A+S+ Sbjct: 136 DFDPGVKEAAAWALGYIARHNTELSQAVVDAGAIPLLVLCIQEPEIALKRIAASALSD-I 194 Query: 420 SGGSHDQIKYLVSEGCIKXXXXXXXXXXXRIVTVCLEGLENILK 551 S S + + +V G I ++ L L I K Sbjct: 195 SKHSPELAQTVVDAGAIAHLAQMILNPDAKLKRQVLSALSQIAK 238 Score = 43.9 bits (102), Expect = 4e-04 Identities = 30/117 (25%), Positives = 57/117 (48%) Frame = +3 Query: 57 IQSVIDAGVCPRLVELLLHPSPSVLIPALRTVGNIVTGDDSQTQCIIDHQALGCLLSLLT 236 I+++ +AGV L LLL P++ A +G + +D + ++ L L+ L Sbjct: 34 IETLQNAGVMSLLRPLLLDVVPTIQQTAALALGRLANYNDDLAEAVVKGDILPQLVYSLA 93 Query: 237 ENHKKSIKKEACWTVSNITAGNKDQIQAVITAGIIFPLVHLLQTAEFDIKKEAAWAI 407 E + + KK A + + + + QA++ G + LV L+ + +K+ AAWA+ Sbjct: 94 EQN-RFYKKAAAFVLRAVGKHSPQLAQAIVDCGALDTLVICLEDFDPGVKEAAAWAL 149 Score = 43.1 bits (100), Expect = 7e-04 Identities = 24/142 (16%), Positives = 62/142 (43%) Frame = +3 Query: 39 RHQXTXIQSVIDAGVCPRLVELLLHPSPSVLIPALRTVGNIVTGDDSQTQCIIDHQALGC 218 +H Q+V+DAG L +++L+P + L + I + +++ + Sbjct: 196 KHSPELAQTVVDAGAIAHLAQMILNPDAKLKRQVLSALSQIAKHSVDLAEMVVEAEIFPV 255 Query: 219 LLSLLTENHKKSIKKEACWTVSNITAGNKDQIQAVITAGIIFPLVHLLQTAEFDIKKEAA 398 +L+ L + + +KK AC + I + Q ++ AG + ++ + + + +I+ Sbjct: 256 VLTCLKDKDEY-VKKNACTLIREIAKHTPELSQLIVNAGGVAAVIDCIGSCKGNIRLPGI 314 Query: 399 WAISNATSGGSHDQIKYLVSEG 464 + + + + ++S+G Sbjct: 315 MMLGYVAAHSENLAMAVIISKG 336 Score = 40.4 bits (93), Expect = 0.004 Identities = 30/123 (24%), Positives = 54/123 (43%) Frame = +3 Query: 39 RHQXTXIQSVIDAGVCPRLVELLLHPSPSVLIPALRTVGNIVTGDDSQTQCIIDHQALGC 218 RH Q+V+DAG P LV + P ++ A + +I Q ++D A+ Sbjct: 154 RHNTELSQAVVDAGAIPLLVLCIQEPEIALKRIAASALSDISKHSPELAQTVVDAGAIAH 213 Query: 219 LLSLLTENHKKSIKKEACWTVSNITAGNKDQIQAVITAGIIFPLVHLLQTAEFDIKKEAA 398 L ++ N +K++ +S I + D + V+ A I ++ L+ + +KK A Sbjct: 214 LAQMIL-NPDAKLKRQVLSALSQIAKHSVDLAEMVVEAEIFPVVLTCLKDKDEYVKKNAC 272 Query: 399 WAI 407 I Sbjct: 273 TLI 275
>SPAG6_HUMAN (O75602) Sperm-associated antigen 6 (PF16 protein homolog) (Sperm| flagellar protein) (Repro-SA-1) Length = 509 Score = 43.5 bits (101), Expect = 5e-04 Identities = 30/117 (25%), Positives = 57/117 (48%) Frame = +3 Query: 57 IQSVIDAGVCPRLVELLLHPSPSVLIPALRTVGNIVTGDDSQTQCIIDHQALGCLLSLLT 236 I+++ +AGV L LLL P++ A +G + +D + ++ L L+ L Sbjct: 34 IETLQNAGVMSLLRTLLLDVVPTIQQTAALALGRLANYNDDLAEAVVKCDILPQLVYSLA 93 Query: 237 ENHKKSIKKEACWTVSNITAGNKDQIQAVITAGIIFPLVHLLQTAEFDIKKEAAWAI 407 E + + KK A + + + + QA++ G + LV L+ + +K+ AAWA+ Sbjct: 94 EQN-RFYKKAAAFVLRAVGKHSPQLAQAIVDCGALDTLVICLEDFDPGVKEAAAWAL 149 Score = 43.1 bits (100), Expect = 7e-04 Identities = 33/118 (27%), Positives = 55/118 (46%) Frame = +3 Query: 60 QSVIDAGVCPRLVELLLHPSPSVLIPALRTVGNIVTGDDSQTQCIIDHQALGCLLSLLTE 239 ++V+ + P+LV L + A + + Q I+D AL L+ L E Sbjct: 77 EAVVKCDILPQLVYSLAEQNRFYKKAAAFVLRAVGKHSPQLAQAIVDCGALDTLVICL-E 135 Query: 240 NHKKSIKKEACWTVSNITAGNKDQIQAVITAGIIFPLVHLLQTAEFDIKKEAAWAISN 413 + +K+ A W + I N + QAV+ AG + LV +Q E +K+ AA A+S+ Sbjct: 136 DFDPGVKEAAAWALRYIARHNAELSQAVVDAGAVPLLVLCIQEPEIALKRIAASALSD 193 Score = 39.7 bits (91), Expect = 0.008 Identities = 29/123 (23%), Positives = 55/123 (44%) Frame = +3 Query: 39 RHQXTXIQSVIDAGVCPRLVELLLHPSPSVLIPALRTVGNIVTGDDSQTQCIIDHQALGC 218 RH Q+V+DAG P LV + P ++ A + +I Q ++D A+ Sbjct: 154 RHNAELSQAVVDAGAVPLLVLCIQEPEIALKRIAASALSDIAKHSPELAQTVVDAGAVAH 213 Query: 219 LLSLLTENHKKSIKKEACWTVSNITAGNKDQIQAVITAGIIFPLVHLLQTAEFDIKKEAA 398 L ++ N +K + +S ++ + D + V+ A I ++ L+ + +KK A+ Sbjct: 214 LAQMIL-NPDAKLKHQILSALSQVSKHSVDLAEMVVEAEIFPVVLTCLKDKDEYVKKNAS 272 Query: 399 WAI 407 I Sbjct: 273 TLI 275
>PUB14_ARATH (Q8VZ40) E3 ubiquitin ligase PUB14 (EC 6.3.2.-) (Prototypical U-box| domain protein 14) Length = 632 Score = 40.8 bits (94), Expect = 0.003 Identities = 37/142 (26%), Positives = 70/142 (49%), Gaps = 10/142 (7%) Frame = +3 Query: 66 VIDAGVCPRLVELLLHPSPSVLIPALRTVGNIVTGDDSQTQCIIDHQALGCLLSLLTENH 245 + +AG P LVELL P P ++ + N+ + ++ I+D A+ ++ +L +N Sbjct: 383 IAEAGAIPLLVELLSSPDPRTQEHSVTALLNLSINEGNK-GAIVDAGAITDIVEVL-KNG 440 Query: 246 KKSIKKEACWTVSNITAGNKDQIQAVITAGIIFPLVHLLQTAEFDIKKEAAWAI------ 407 ++ A T+ +++ +++++ A+ AG I L+ LL+ KK+AA AI Sbjct: 441 SMEARENAAATLFSLSVIDENKV-AIGAAGAIQALISLLEEGTRRGKKDAATAIFNLCIY 499 Query: 408 ----SNATSGGSHDQIKYLVSE 461 S A GG D + L+ + Sbjct: 500 QGNKSRAVKGGIVDPLTRLLKD 521
>PLAK_RAT (Q6P0K8) Junction plakoglobin| Length = 745 Score = 37.7 bits (86), Expect = 0.029 Identities = 40/189 (21%), Positives = 75/189 (39%), Gaps = 15/189 (7%) Frame = +3 Query: 33 SLRHQXTXIQSVIDAGVCPRLVELLLHPSPSVLIPALRTVGNIVTGDDSQTQCIIDHQAL 212 +L H + ++ +G P LV +L P SVL A+ T+ N++ + + L Sbjct: 211 NLSHHREGLLAIFKSGGIPALVRMLSSPVESVLFYAITTLHNLLLYQEGAKMAVRLADGL 270 Query: 213 GCLLSLLTENHKKSIKKEACWTVSNITAGNKDQIQAVITAGIIFPLVHLLQTAEFDIKKE 392 ++ LL +N+ K + + + GN++ ++ G LV +++ ++ + Sbjct: 271 QKMVPLLNKNNPKFLAITTD-CLQLLAYGNQESKLIILANGGPQGLVQIMRNYSYE---K 326 Query: 393 AAWAISNATSGGS--HDQIKYLVSEGCIKXXXXXXXXXXXRIVTVCL------------- 527 W S S +V G ++ R+V CL Sbjct: 327 LLWTTSRVLKVLSVCPSNKPAIVEAGGMQALGKHLTSNSPRLVQNCLWTLRNLSDVATKQ 386 Query: 528 EGLENILKV 554 EGLEN+LK+ Sbjct: 387 EGLENVLKI 395
>GDS1A_XENLA (O93614) Rap1 GTPase-GDP dissociation stimulator 1-A (RalB-binding| protein-A) (Rap1gds1-A protein) (smgGDS-A) (XsmgGDS-A) Length = 607 Score = 37.7 bits (86), Expect = 0.029 Identities = 29/107 (27%), Positives = 46/107 (42%), Gaps = 9/107 (8%) Frame = +3 Query: 69 IDAGVCPRLVELLLHPSPSVLIPALRTVGNI---------VTGDDSQTQCIIDHQALGCL 221 ++AG+ P LV+LL VL+ R +GNI + Q ++DH C Sbjct: 86 VEAGLIPPLVQLLHSKDQEVLLQTGRALGNICYDNHEGRRAVDQEGGAQIVVDHLRSMC- 144 Query: 222 LSLLTENHKKSIKKEACWTVSNITAGNKDQIQAVITAGIIFPLVHLL 362 LT+ + + C + N ++ N +I G+I LV LL Sbjct: 145 --TLTDPSSEKLMTVFCGMLMNYSSENDSLQTQLIQMGVIPILVDLL 189
>CTND2_MOUSE (O35927) Catenin delta-2 (Neural plakophilin-related ARM-repeat| protein) (NPRAP) (Neurojungin) Length = 1247 Score = 35.0 bits (79), Expect = 0.19 Identities = 30/115 (26%), Positives = 54/115 (46%), Gaps = 3/115 (2%) Frame = +3 Query: 87 PRLVELLLHPSPSVLIPALRTVGNIVTGDDSQTQCIIDHQALGCLLSLLTENHKKSIKKE 266 P ++++L H PSV A + ++ GD+ I + L+ LL ++ + + Sbjct: 550 PEVIQMLQHQFPSVQSNAAAYLQHLCFGDNKIKAEIRRQGGIQLLVDLL-DHRMTEVHRS 608 Query: 267 ACWTVSNITAG--NKDQIQAVITAGIIFPLVHLL-QTAEFDIKKEAAWAISNATS 422 AC + N+ G N D A+ G I LV LL +T + +I++ + N +S Sbjct: 609 ACGALRNLVYGKANDDNKIALKNCGGIPALVRLLRKTTDLEIRELVTGVLWNLSS 663
>CTND2_HUMAN (Q9UQB3) Catenin delta-2 (Delta-catenin) (Neural| plakophilin-related ARM-repeat protein) (NPRAP) (Neurojungin) (GT24) Length = 1225 Score = 35.0 bits (79), Expect = 0.19 Identities = 30/115 (26%), Positives = 54/115 (46%), Gaps = 3/115 (2%) Frame = +3 Query: 87 PRLVELLLHPSPSVLIPALRTVGNIVTGDDSQTQCIIDHQALGCLLSLLTENHKKSIKKE 266 P ++++L H PSV A + ++ GD+ I + L+ LL ++ + + Sbjct: 553 PEVIQMLQHQFPSVQSNAAAYLQHLCFGDNKIKAEIRRQGGIQLLVDLL-DHRMTEVHRS 611 Query: 267 ACWTVSNITAG--NKDQIQAVITAGIIFPLVHLL-QTAEFDIKKEAAWAISNATS 422 AC + N+ G N D A+ G I LV LL +T + +I++ + N +S Sbjct: 612 ACGALRNLVYGKANDDNKIALKNCGGIPALVRLLRKTTDLEIRELVTGVLWNLSS 666
>GDS1_BOVIN (Q04173) Rap1 GTPase-GDP dissociation stimulator 1 (SMG P21| stimulatory GDP/GTP exchange protein) (SMG GDS protein) (Exchange factor smgGDS) Length = 558 Score = 33.1 bits (74), Expect = 0.72 Identities = 34/136 (25%), Positives = 57/136 (41%), Gaps = 1/136 (0%) Frame = +3 Query: 69 IDAGVCPRLVELLLHPSPSVLIPALRTVGNIVTGDDSQTQCIIDHQALGCLLSLLTENHK 248 +DAG+ LV+LL VL+ R +GNI S +I+ + L+ LL + + Sbjct: 86 VDAGLISPLVQLLNSKDQEVLLQTGRALGNICYDSHSLQAQLINMGVIPTLVKLLGIHCQ 145 Query: 249 KSIKKEACWTVSNITAGNKDQIQAVITAGIIFPLVHLLQTAEFDIKKEAAWAISNATSGG 428 K+ E C A + + + I LV L + K+E + + + Sbjct: 146 KAALTEMCLVAFGNLAELESSKEQFASTNIAEELVKLFKKQIEHDKREMVFEVLAPLA-- 203 Query: 429 SHDQIK-YLVSEGCIK 473 +D IK LV G ++ Sbjct: 204 ENDAIKLQLVESGLVE 219
>GDS1_HUMAN (P52306) Rap1 GTPase-GDP dissociation stimulator 1 (SMG P21| stimulatory GDP/GTP exchange protein) (SMG GDS protein) (Exchange factor smgGDS) Length = 607 Score = 33.1 bits (74), Expect = 0.72 Identities = 32/108 (29%), Positives = 47/108 (43%), Gaps = 10/108 (9%) Frame = +3 Query: 69 IDAGVCPRLVELLLHPSPSVLIPALRTVGNI---------VTGDDSQTQCIIDHQALGCL 221 +DAG+ LV+LL VL+ R +GNI Q +IDH C Sbjct: 86 VDAGLISPLVQLLNSKDQEVLLQTGRALGNICYDSHEGRSAVDQAGGAQIVIDHLRSLC- 144 Query: 222 LSLLTENHKKSIKKEACWTVSNITAGNKDQIQA-VITAGIIFPLVHLL 362 +T+ + + C + N + N D +QA +I G+I LV LL Sbjct: 145 --SITDPANEKLLTVFCGMLMNYSNEN-DSLQAQLINMGVIPTLVKLL 189
>POLN_LORDV (P54634) Non-structural polyprotein [Contains: p48; Helicase (2C-like| protein) (P2C); 3A-like protein; Viral genome-linked protein (VPg); Thiol protease P3C (EC 3.4.22.-) (3C-like protease) (3C-pro); RNA-directed RNA polymerase (EC 2.7.7.48)] Length = 1699 Score = 32.0 bits (71), Expect = 1.6 Identities = 20/66 (30%), Positives = 27/66 (40%) Frame = +3 Query: 114 PSPSVLIPALRTVGNIVTGDDSQTQCIIDHQALGCLLSLLTENHKKSIKKEACWTVSNIT 293 P PSVL A RT+ N++ Q QA L + H ++K CW + T Sbjct: 1267 PKPSVLEAAKRTIINVLEQTIDPPQKWSFTQACASLDKTTSSGHPHHMRKNDCWNGESFT 1326 Query: 294 AGNKDQ 311 DQ Sbjct: 1327 GKLADQ 1332
>YL045_MIMIV (Q5UPB6) Putative ankyrin repeat protein L45| Length = 227 Score = 31.2 bits (69), Expect = 2.7 Identities = 26/92 (28%), Positives = 42/92 (45%) Frame = +3 Query: 192 IIDHQALGCLLSLLTENHKKSIKKEACWTVSNITAGNKDQIQAVITAGIIFPLVHLLQTA 371 IID + L L+ +N K I K +NI + G I +V L + Sbjct: 73 IIDIRCLEESLNASCKNGKLEIVKLLVDLGANIFHNENCAMMLASEYGHI-EIVEYLVSK 131 Query: 372 EFDIKKEAAWAISNATSGGSHDQIKYLVSEGC 467 D++ + +A+ A+ G + +KYLVS+GC Sbjct: 132 GSDVRADNDYAVIYASKNGHLEIVKYLVSQGC 163
>DLD1_YEAST (P32891) D-lactate dehydrogenase [cytochrome] 1, mitochondrial| precursor (EC 1.1.2.4) (D-lactate ferricytochrome C oxidoreductase) (D-LCR) Length = 587 Score = 31.2 bits (69), Expect = 2.7 Identities = 20/84 (23%), Positives = 36/84 (42%), Gaps = 3/84 (3%) Frame = +3 Query: 231 LTENHKKSIKKEACWTVSNITAGNKDQIQAVITAGI---IFPLVHLLQTAEFDIKKEAAW 401 + + K+ K A + ++ + G++ + V A + + P + FD K+AA Sbjct: 287 IVKTKKRPRKSSAGYNLNGLFVGSEGTLGIVTEATVKCHVKPKAETVAVVSFDTIKDAAA 346 Query: 402 AISNATSGGSHDQIKYLVSEGCIK 473 SN T G H L+ E +K Sbjct: 347 CASNLTQSGIHLNAMELLDENMMK 370
>YL112_MIMIV (Q5UPI6) Putative ankyrin repeat protein L112| Length = 457 Score = 30.8 bits (68), Expect = 3.6 Identities = 20/87 (22%), Positives = 38/87 (43%), Gaps = 18/87 (20%) Frame = +3 Query: 258 KKEACWTVSNIT-AGNKDQIQAVITAGI------IFPLVHLLQTAEFDIKK--------- 389 +KE CW +++ G+ + I+ +++ GI + H +T +I K Sbjct: 248 RKEKCWAITSACQGGHLNIIEFLLSLGIKPKEINVDAFYHACKTGNLEIAKYLKEIGADT 307 Query: 390 --EAAWAISNATSGGSHDQIKYLVSEG 464 WA+ + GG D +KY++ G Sbjct: 308 ITRRDWALELSARGGYLDVVKYIIELG 334
>SIAE_MOUSE (P70665) Sialate O-acetylesterase precursor (EC 3.1.1.53) (Sialic| acid-specific 9-O-acetylesterase) (Yolk sac protein 2) [Contains: Sialate O-acetylesterase small subunit; Sialate O-acetylesterase large subunit] Length = 541 Score = 30.4 bits (67), Expect = 4.6 Identities = 12/37 (32%), Positives = 21/37 (56%) Frame = -3 Query: 636 FPGLLLHQSSVHRHFPPQKHPNSYQSLQL*ECSQDPP 526 FP + HQ++ H P K PN++ ++ + C +D P Sbjct: 362 FPEIRWHQTADFGHVPNPKMPNTFMAVAIDLCDRDSP 398
>YR873_MIMIV (Q5UP39) Putative ankyrin repeat protein R873| Length = 468 Score = 30.4 bits (67), Expect = 4.6 Identities = 17/65 (26%), Positives = 31/65 (47%) Frame = +3 Query: 270 CWTVSNITAGNKDQIQAVITAGIIFPLVHLLQTAEFDIKKEAAWAISNATSGGSHDQIKY 449 CW N G+ + ++ +++ G+ +I+ WAI A+ G + +KY Sbjct: 174 CWASGN---GHLEMVKYLVSQGV-------------NIRTNDDWAIRLASENGHLEVVKY 217 Query: 450 LVSEG 464 LVS+G Sbjct: 218 LVSQG 222
>YR810_MIMIV (Q5UQ36) Putative ankyrin repeat protein R810| Length = 211 Score = 30.0 bits (66), Expect = 6.1 Identities = 18/40 (45%), Positives = 21/40 (52%) Frame = +3 Query: 345 PLVHLLQTAEFDIKKEAAWAISNATSGGSHDQIKYLVSEG 464 P+V L + DI E I NAT G D +KYLVS G Sbjct: 87 PIVKYLVSKGADICAEQNSPIKNATYYGHLDVVKYLVSNG 126
>IMB3_YEAST (P32337) Importin beta-3 subunit (Karyopherin beta-3 subunit)| (Protein secretion enhancer 1) Length = 1089 Score = 29.6 bits (65), Expect = 7.9 Identities = 26/128 (20%), Positives = 51/128 (39%), Gaps = 4/128 (3%) Frame = +3 Query: 78 GVCPRLVELLL----HPSPSVLIPALRTVGNIVTGDDSQTQCIIDHQALGCLLSLLTENH 245 G P+++++++ P P V +G I T Q + L L+S LT Sbjct: 404 GEIPKILDMVIPLINDPHPRVQYGCCNVLGQISTDFSPFIQRTAHDRILPALISKLTSEC 463 Query: 246 KKSIKKEACWTVSNITAGNKDQIQAVITAGIIFPLVHLLQTAEFDIKKEAAWAISNATSG 425 ++ A + N + I ++ L+ LLQ+ + ++++A I+ Sbjct: 464 TSRVQTHAAAALVNFSEFASKDILEPYLDSLLTNLLVLLQSNKLYVQEQALTTIAFIAEA 523 Query: 426 GSHDQIKY 449 + IKY Sbjct: 524 AKNKFIKY 531
>ADH5_YEAST (P38113) Alcohol dehydrogenase 5 (EC 1.1.1.1) (Alcohol| dehydrogenase V) Length = 351 Score = 29.6 bits (65), Expect = 7.9 Identities = 15/34 (44%), Positives = 20/34 (58%) Frame = +3 Query: 372 EFDIKKEAAWAISNATSGGSHDQIKYLVSEGCIK 473 +F +K+ AI AT+GGSH I VSE I+ Sbjct: 224 DFTEEKDIVGAIIKATNGGSHGVINVSVSEAAIE 257
>ADH5_SACPS (Q6XQ67) Alcohol dehydrogenase 5 (EC 1.1.1.1) (Alcohol| dehydrogenase V) Length = 351 Score = 29.6 bits (65), Expect = 7.9 Identities = 15/34 (44%), Positives = 20/34 (58%) Frame = +3 Query: 372 EFDIKKEAAWAISNATSGGSHDQIKYLVSEGCIK 473 +F +K+ AI AT+GGSH I VSE I+ Sbjct: 224 DFTEEKDIVGAIIKATNGGSHGVINVSVSEAAIE 257
>YR863_MIMIV (Q5UQJ2) Putative ankyrin repeat protein R863| Length = 514 Score = 29.6 bits (65), Expect = 7.9 Identities = 20/61 (32%), Positives = 33/61 (54%) Frame = +3 Query: 282 SNITAGNKDQIQAVITAGIIFPLVHLLQTAEFDIKKEAAWAISNATSGGSHDQIKYLVSE 461 +NI A N ++ G I +V L + DI+ + +AI +A+ GG + ++YLVS Sbjct: 200 ANIRADNNYAVRLASENGHI-DVVKYLVSLGADIRADNNYAIRHASRGGHIEVVEYLVSL 258 Query: 462 G 464 G Sbjct: 259 G 259 Database: uniprot_sprot.fasta Posted date: May 25, 2006 5:36 PM Number of letters in database: 80,573,946 Number of sequences in database: 219,361 Lambda K H 0.318 0.135 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 92,905,528 Number of Sequences: 219361 Number of extensions: 1914429 Number of successful extensions: 5862 Number of sequences better than 10.0: 47 Number of HSP's better than 10.0 without gapping: 5382 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 5727 length of database: 80,573,946 effective HSP length: 107 effective length of database: 57,102,319 effective search space used: 5995743495 frameshift window, decay const: 50, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
