ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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| Clone Name | bags9a04 |
|---|---|
| Clone Library Name | barley_pub |
>LEU22_METJA (P81291) 3-isopropylmalate dehydratase large subunit 2 (EC| 4.2.1.33) (Isopropylmalate isomerase 2) (Alpha-IPM isomerase 2) (IPMI 2) Length = 424 Score = 175 bits (444), Expect = 8e-44 Identities = 83/163 (50%), Positives = 110/163 (67%) Frame = +3 Query: 120 FCQEQKIKYFYDIKDLSDFRANPDYKGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQ 299 F +EQ IKYFYDI++ GVCH L ++GH PGEV++G DSHTC GAFG Sbjct: 85 FVKEQGIKYFYDIRE-----------GVCHQVLPEKGHVAPGEVVVGADSHTCTHGAFGA 133 Query: 300 FATGIGNTDAGFVMGTGKALLKVPPTIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYR 479 FATGIG+TD V TGK KVP TI F + G++ PY+ +KD+IL IIGE+ V GATY+ Sbjct: 134 FATGIGSTDMAHVFATGKLWFKVPETIYFNITGDLQPYVTSKDVILSIIGEVGVDGATYK 193 Query: 480 SMEFVGSTIESLTMEERMTLCNMVIEAGGKNGVVPADETTFKY 608 + +F G T++ +++ RMT+ NM IE GGK G++ DE T +Y Sbjct: 194 ACQFGGETVKKMSIASRMTMTNMAIEMGGKTGIIEPDEKTIQY 236
>LEU21_METKA (Q8TVF2) 3-isopropylmalate dehydratase large subunit 1 (EC| 4.2.1.33) (Isopropylmalate isomerase 1) (Alpha-IPM isomerase 1) (IPMI 1) Length = 418 Score = 164 bits (415), Expect = 2e-40 Identities = 76/163 (46%), Positives = 106/163 (65%) Frame = +3 Query: 120 FCQEQKIKYFYDIKDLSDFRANPDYKGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQ 299 F +EQ I++FYD+++ GVCH L ++GH RPG+V++G DSHTC GA G Sbjct: 84 FVEEQGIEHFYDVRE-----------GVCHQVLPEKGHVRPGDVIVGADSHTCTHGALGA 132 Query: 300 FATGIGNTDAGFVMGTGKALLKVPPTIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYR 479 FATGIG+TD V TGK +VP T R + GE+P + AKD++L++ GEI GATY Sbjct: 133 FATGIGSTDMAAVFATGKLWFRVPETYRVEITGELPEGVYAKDVVLKVTGEIGADGATYM 192 Query: 480 SMEFVGSTIESLTMEERMTLCNMVIEAGGKNGVVPADETTFKY 608 ++E+ G + +++ +RM LCNM IE G K G+VP DE T +Y Sbjct: 193 AIEYHGEVVREMSVSDRMCLCNMAIEMGAKTGMVPPDEKTLEY 235
>LEU21_METTH (O27439) 3-isopropylmalate dehydratase large subunit 1 (EC| 4.2.1.33) (Isopropylmalate isomerase 1) (Alpha-IPM isomerase 1) (IPMI 1) Length = 419 Score = 162 bits (410), Expect = 7e-40 Identities = 78/163 (47%), Positives = 104/163 (63%) Frame = +3 Query: 120 FCQEQKIKYFYDIKDLSDFRANPDYKGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQ 299 F +EQ I+ FYD+++ GVCH L ++GH PGEV++GTDSHTC GA G Sbjct: 85 FVEEQGIRNFYDVRE-----------GVCHQVLPEKGHVVPGEVVVGTDSHTCTHGALGA 133 Query: 300 FATGIGNTDAGFVMGTGKALLKVPPTIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYR 479 FATGIG+TD V TGK +VP T+RF + G++ ++ AKD+IL IIG + GATY Sbjct: 134 FATGIGSTDMAMVFATGKLWFRVPETLRFDVRGKLREHVYAKDVILNIIGRVGADGATYM 193 Query: 480 SMEFVGSTIESLTMEERMTLCNMVIEAGGKNGVVPADETTFKY 608 + EF G T+ +++ +RM L NM IE GGK G+V DE T Y Sbjct: 194 ACEFAGETVAEMSVSDRMVLSNMAIEMGGKTGIVEPDEKTLNY 236
>LEU2_WOLSU (Q7M9Z9) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 422 Score = 157 bits (397), Expect = 2e-38 Identities = 74/163 (45%), Positives = 110/163 (67%) Frame = +3 Query: 120 FCQEQKIKYFYDIKDLSDFRANPDYKGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQ 299 F ++ ++K+++D +D+ G+ H L ++G PG+V++G DSHTC GA G Sbjct: 84 FAKKHQLKHYFDERDM----------GIEHAILPEKGLVLPGDVIIGADSHTCTHGALGA 133 Query: 300 FATGIGNTDAGFVMGTGKALLKVPPTIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYR 479 FATG+G+TD + M TGK KVPP+IR V G++ ++ KDLIL+II +I V GA Y+ Sbjct: 134 FATGMGSTDLAYAMITGKNWFKVPPSIRVVFKGKLQEHVYGKDLILEIIRQIGVDGALYK 193 Query: 480 SMEFVGSTIESLTMEERMTLCNMVIEAGGKNGVVPADETTFKY 608 ++EF G TIE L+M++R +LCNM IEAG KNG++ AD T ++ Sbjct: 194 ALEFQGDTIEQLSMDDRFSLCNMAIEAGAKNGIIAADSITKEF 236
>LEU22_METMA (Q8PUG1) 3-isopropylmalate dehydratase large subunit 2 (EC| 4.2.1.33) (Isopropylmalate isomerase 2) (Alpha-IPM isomerase 2) (IPMI 2) Length = 420 Score = 157 bits (396), Expect = 3e-38 Identities = 70/139 (50%), Positives = 99/139 (71%) Frame = +3 Query: 192 YKGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFATGIGNTDAGFVMGTGKALLKVP 371 Y+GVCH L ++GH +PG++++G+DSHTC G+ G F+TGIG+TD V TGK +VP Sbjct: 98 YEGVCHQVLPEKGHVKPGDLIVGSDSHTCAYGSLGAFSTGIGSTDMAAVFATGKLWFRVP 157 Query: 372 PTIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMV 551 T RF ++G++P + +KDLIL +IG++ V G Y + E+ GSTI SL++ ERMT+ NM Sbjct: 158 ETFRFEVEGKLPERVYSKDLILHLIGDVGVEGVRYMAAEYAGSTIRSLSIPERMTMSNMA 217 Query: 552 IEAGGKNGVVPADETTFKY 608 IE GGK G++ ADE T Y Sbjct: 218 IEMGGKAGIIEADEVTEAY 236
>LEU22_METAC (Q8TQZ3) 3-isopropylmalate dehydratase large subunit 2 (EC| 4.2.1.33) (Isopropylmalate isomerase 2) (Alpha-IPM isomerase 2) (IPMI 2) Length = 420 Score = 157 bits (396), Expect = 3e-38 Identities = 71/139 (51%), Positives = 99/139 (71%) Frame = +3 Query: 192 YKGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFATGIGNTDAGFVMGTGKALLKVP 371 Y+GVCH L ++GH PG++++G+DSHTC G+ G F+TGIG+TD V TGK +VP Sbjct: 98 YEGVCHQVLPEKGHVLPGDLIVGSDSHTCAYGSLGAFSTGIGSTDMAAVFATGKLWFRVP 157 Query: 372 PTIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMV 551 T RF ++G++P + +KDLIL +IG++ V GA Y + E+ GSTI SL++ ERMT+ NM Sbjct: 158 ETFRFEVEGKLPERVYSKDLILHLIGDVGVEGARYMAAEYAGSTIRSLSIPERMTISNMA 217 Query: 552 IEAGGKNGVVPADETTFKY 608 IE GGK G++ ADE T Y Sbjct: 218 IEMGGKAGIIEADEVTEAY 236
>LEU21_PYRFU (Q8U2A1) 3-isopropylmalate dehydratase large subunit 1 (EC| 4.2.1.33) (Isopropylmalate isomerase 1) (Alpha-IPM isomerase 1) (IPMI 1) Length = 424 Score = 155 bits (392), Expect = 9e-38 Identities = 76/163 (46%), Positives = 108/163 (66%) Frame = +3 Query: 120 FCQEQKIKYFYDIKDLSDFRANPDYKGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQ 299 F +EQ IK+F++ ++ GV H L + G PGE+++G DSHTC GA G Sbjct: 86 FAREQGIKWFFEGGNV----------GVEHCLLPELGLVLPGELIIGADSHTCTYGALGA 135 Query: 300 FATGIGNTDAGFVMGTGKALLKVPPTIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYR 479 FATG+G+TD M TG+A +VP TI+FV +G++ P++ +KDLIL IG+I V+GA Y+ Sbjct: 136 FATGVGSTDLAVAMATGEAWFRVPETIKFVYEGDLQPWVTSKDLILYTIGDIGVNGALYK 195 Query: 480 SMEFVGSTIESLTMEERMTLCNMVIEAGGKNGVVPADETTFKY 608 MEF G IE L++E+RMT+ NM IEAG K G++ D+ T +Y Sbjct: 196 VMEFSGEVIEKLSVEQRMTMTNMAIEAGAKTGIIEPDKKTIEY 238
>LEU2_AQUAE (O67078) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 432 Score = 155 bits (392), Expect = 9e-38 Identities = 72/163 (44%), Positives = 110/163 (67%) Frame = +3 Query: 120 FCQEQKIKYFYDIKDLSDFRANPDYKGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQ 299 F ++ IK+F++ + +G+ H L ++G PG++++G DSHTC GA G Sbjct: 85 FVKKHGIKWFFE-----------EGEGIEHAILPEQGLVVPGDLVVGADSHTCTYGALGA 133 Query: 300 FATGIGNTDAGFVMGTGKALLKVPPTIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYR 479 FATG+G+TD + M TG+ L+VP +++F+ G++ P+++ KDLIL IG+I V GA YR Sbjct: 134 FATGVGSTDIAYAMATGEVWLRVPESMKFIFYGKLKPWVMGKDLILYTIGQIGVDGALYR 193 Query: 480 SMEFVGSTIESLTMEERMTLCNMVIEAGGKNGVVPADETTFKY 608 +MEF G TI +L+ME+R T+ NM IEAGGK+G++ DE T +Y Sbjct: 194 AMEFDGETIRNLSMEQRFTIANMAIEAGGKSGIISPDEKTIEY 236
>LEU21_PYRAB (Q9UZ07) 3-isopropylmalate dehydratase large subunit 1 (EC| 4.2.1.33) (Isopropylmalate isomerase 1) (Alpha-IPM isomerase 1) (IPMI 1) Length = 423 Score = 154 bits (389), Expect = 2e-37 Identities = 75/163 (46%), Positives = 105/163 (64%) Frame = +3 Query: 120 FCQEQKIKYFYDIKDLSDFRANPDYKGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQ 299 F +E IK+F++ + GV H L + G PG++++G DSHTC GA G Sbjct: 85 FAKEMGIKWFFEGGSV----------GVEHCLLPELGLVLPGDLIIGADSHTCTYGALGA 134 Query: 300 FATGIGNTDAGFVMGTGKALLKVPPTIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYR 479 FATG+G+TD M TG+A +VP T++F+ +GE+ PY+ KDLIL IG+I V+GA Y+ Sbjct: 135 FATGVGSTDLAVAMATGEAWFRVPETMKFIYEGELQPYVTGKDLILHTIGDIGVNGALYK 194 Query: 480 SMEFVGSTIESLTMEERMTLCNMVIEAGGKNGVVPADETTFKY 608 MEF GS IE L++E+RMT+ NM IEAG K G++ D+ T Y Sbjct: 195 VMEFSGSVIEELSVEQRMTMSNMAIEAGAKTGIIEPDKKTLDY 237
>LEU22_METTH (O27668) 3-isopropylmalate dehydratase large subunit 2 (EC| 4.2.1.33) (Isopropylmalate isomerase 2) (Alpha-IPM isomerase 2) (IPMI 2) Length = 428 Score = 153 bits (387), Expect = 3e-37 Identities = 84/202 (41%), Positives = 106/202 (52%) Frame = +3 Query: 3 SSGXDAKVWDREXGXXXXXXXXXXXXXAGQXXXXXXXGXFCQEQKIKYFYDIKDLSDFRA 182 S G A+VWD E G F +EQ I + Sbjct: 52 SRGGPARVWDPER-IVMVFDHNVPANTIGAAEFQRVTREFAREQGIVNIFQ--------- 101 Query: 183 NPDYKGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFATGIGNTDAGFVMGTGKALL 362 + G+CH L + G RPG V++G DSHTC GAFG FATG+G TD V TGK Sbjct: 102 --NAAGICHQVLPERGFVRPGMVIVGADSHTCTYGAFGAFATGMGATDMAMVFATGKTWF 159 Query: 363 KVPPTIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLC 542 VP +R + GE ++ AKD+IL IIGEI V GATYRS+EF G TIES+ + RMT+C Sbjct: 160 MVPEAMRIEVTGEPEGHVYAKDVILHIIGEIGVDGATYRSVEFTGDTIESMDVSGRMTIC 219 Query: 543 NMVIEAGGKNGVVPADETTFKY 608 NM +E G KNG++ + T Y Sbjct: 220 NMAVEMGAKNGIMEPNRQTLDY 241
>LEU21_METMA (Q8PZT3) 3-isopropylmalate dehydratase large subunit 1 (EC| 4.2.1.33) (Isopropylmalate isomerase 1) (Alpha-IPM isomerase 1) (IPMI 1) Length = 391 Score = 151 bits (382), Expect = 1e-36 Identities = 72/161 (44%), Positives = 100/161 (62%) Frame = +3 Query: 126 QEQKIKYFYDIKDLSDFRANPDYKGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFA 305 +EQ I FY+I + G+CH L + G PG++L+G DSH+C GAFG FA Sbjct: 63 REQSIPNFYEIGE-----------GICHQVLPENGFALPGKLLVGADSHSCTYGAFGAFA 111 Query: 306 TGIGNTDAGFVMGTGKALLKVPPTIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSM 485 TG+G TD + TGK KVP + R ++G + ++ AKDL L +IG+ ++GATY+++ Sbjct: 112 TGVGATDMAEIFATGKLWFKVPESFRMTVEGSLDKHVYAKDLTLYLIGKTGIAGATYKAV 171 Query: 486 EFVGSTIESLTMEERMTLCNMVIEAGGKNGVVPADETTFKY 608 EF G I L++ RMTLCNM IE G K G+VP DE TF + Sbjct: 172 EFYGQAISELSVAGRMTLCNMAIEMGAKTGIVPPDEKTFDF 212
>LEU2_CLOAB (Q97EE0) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 422 Score = 150 bits (378), Expect = 4e-36 Identities = 72/163 (44%), Positives = 105/163 (64%) Frame = +3 Query: 120 FCQEQKIKYFYDIKDLSDFRANPDYKGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQ 299 F + ++I+ +++I ++ G+ H + ++G PG+V++G DSHTC GA G Sbjct: 87 FAKSKEIENYFEIGEM----------GIEHALIPEKGLAVPGDVIIGADSHTCTYGALGV 136 Query: 300 FATGIGNTDAGFVMGTGKALLKVPPTIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYR 479 F+TG+G+TD M TGKA KVP I+FVL G+ ++ KD+IL IIG I V GA Y+ Sbjct: 137 FSTGVGSTDMAVGMATGKAWFKVPEAIKFVLKGKPAKWVSGKDIILHIIGMIGVDGALYK 196 Query: 480 SMEFVGSTIESLTMEERMTLCNMVIEAGGKNGVVPADETTFKY 608 SME+ G +E L+M++R T+ NM IEAG KNG+ P DE T +Y Sbjct: 197 SMEYTGDGLEYLSMDDRFTIANMAIEAGAKNGIFPVDEKTIEY 239
>LEU21_METAC (Q8TLF1) 3-isopropylmalate dehydratase large subunit 1 (EC| 4.2.1.33) (Isopropylmalate isomerase 1) (Alpha-IPM isomerase 1) (IPMI 1) Length = 424 Score = 149 bits (376), Expect = 6e-36 Identities = 71/161 (44%), Positives = 100/161 (62%) Frame = +3 Query: 126 QEQKIKYFYDIKDLSDFRANPDYKGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFA 305 +EQ I FY++ + G+CH L + G PG++++G DSH+C GAFG FA Sbjct: 96 KEQGIPNFYEVGE-----------GICHQVLPENGFALPGKLVVGADSHSCTYGAFGAFA 144 Query: 306 TGIGNTDAGFVMGTGKALLKVPPTIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSM 485 TG+G TD + TGK KVP + R ++G + + AKDL L +IG+ ++GATY+++ Sbjct: 145 TGVGATDMAEIFATGKLWFKVPESFRMTVEGSLRKGVYAKDLTLYLIGKTGIAGATYKAV 204 Query: 486 EFVGSTIESLTMEERMTLCNMVIEAGGKNGVVPADETTFKY 608 EF G I LT+ RMTLCNM IE G K G+VP DE TF++ Sbjct: 205 EFYGQAIRELTVAGRMTLCNMAIEMGAKTGIVPPDEKTFEF 245
>LEU2_HELHP (Q7VH31) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 420 Score = 144 bits (364), Expect = 2e-34 Identities = 70/163 (42%), Positives = 104/163 (63%) Frame = +3 Query: 120 FCQEQKIKYFYDIKDLSDFRANPDYKGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQ 299 F ++ I ++YD+ ++ GV H L ++G G++++G DSHTC GA G Sbjct: 85 FAKDFDISHYYDVGNM----------GVEHALLPEQGIVTIGDLIIGADSHTCTYGALGA 134 Query: 300 FATGIGNTDAGFVMGTGKALLKVPPTIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYR 479 F+TG+G+TD M TG+A KVP I+F L G++ PY+ KD+IL IIG+I V GA Y+ Sbjct: 135 FSTGVGSTDMAVGMATGQAWFKVPYAIKFNLKGKLRPYVSGKDVILHIIGKIGVDGALYK 194 Query: 480 SMEFVGSTIESLTMEERMTLCNMVIEAGGKNGVVPADETTFKY 608 SMEF G +++LT+++R+ + NM IEAG KNG+ D+ T Y Sbjct: 195 SMEFGGEGLKNLTIDDRLCIANMAIEAGAKNGIFEVDDITISY 237
>LEU21_ARCFU (O28316) 3-isopropylmalate dehydratase large subunit 1 (EC| 4.2.1.33) (Isopropylmalate isomerase 1) (Alpha-IPM isomerase 1) (IPMI 1) Length = 418 Score = 143 bits (360), Expect = 4e-34 Identities = 77/200 (38%), Positives = 108/200 (54%) Frame = +3 Query: 9 GXDAKVWDREXGXXXXXXXXXXXXXAGQXXXXXXXGXFCQEQKIKYFYDIKDLSDFRANP 188 G DAKVWD+ F +EQ I YD+K Sbjct: 50 GSDAKVWDKSK-VIMAFDHQVPADSVHAAENHKMLRKFAEEQGI-LNYDVKG-------- 99 Query: 189 DYKGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFATGIGNTDAGFVMGTGKALLKV 368 G+ H + E H PG +++G DSHTC GA G FATGIG+TD GFV+ GK KV Sbjct: 100 ---GIAH-QIMVENHVEPGMLIVGADSHTCMYGALGAFATGIGSTDMGFVLAMGKLWFKV 155 Query: 369 PPTIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNM 548 P +IRF + G++ ++ KD++L++IG + GA Y++ + G +E L M +R+T+CNM Sbjct: 156 PESIRFNVHGKLEKHVYGKDIVLKLIGMVGADGANYKACIYSGEVVEKLGMSDRLTMCNM 215 Query: 549 VIEAGGKNGVVPADETTFKY 608 IE GGK G+V D+TT +Y Sbjct: 216 AIEMGGKAGIVEPDKTTLEY 235
>LEU22_DEIRA (Q9RTI6) 3-isopropylmalate dehydratase large subunit 2 (EC| 4.2.1.33) (Isopropylmalate isomerase 2) (Alpha-IPM isomerase 2) (IPMI 2) Length = 431 Score = 139 bits (351), Expect = 5e-33 Identities = 71/161 (44%), Positives = 96/161 (59%) Frame = +3 Query: 126 QEQKIKYFYDIKDLSDFRANPDYKGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFA 305 QE+ I++FYD+ G+ H+ L G +PG+ L+ DSHTCNAGA G FA Sbjct: 87 QEKGIEHFYDV----------GRGGIAHVVLENTGLMKPGQTLVSGDSHTCNAGALGAFA 136 Query: 306 TGIGNTDAGFVMGTGKALLKVPPTIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSM 485 TG+G+TD + GK KVP T+ + G+ P + KD++L++I +I GA Y M Sbjct: 137 TGVGSTDLAGAIYAGKVWFKVPETMLIRVTGKTNPGVTPKDIVLEVIKQIGADGANYMVM 196 Query: 486 EFVGSTIESLTMEERMTLCNMVIEAGGKNGVVPADETTFKY 608 E+VG I+ L ME R TL NM IEAGGK G+V D+TT Y Sbjct: 197 EWVGDYIDQLDMEGRFTLTNMAIEAGGKTGIVAVDDTTRAY 237
>LEU2_THETN (Q8RDK2) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 418 Score = 139 bits (350), Expect(2) = 8e-33 Identities = 69/137 (50%), Positives = 93/137 (67%) Frame = +3 Query: 198 GVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFATGIGNTDAGFVMGTGKALLKVPPT 377 G+ H L ++G PG+V++G DSHTC GA FATG+G+TD M TGKA KVP Sbjct: 100 GIEHALLPEQGLVLPGDVVIGADSHTCTYGALTCFATGVGSTDMAAAMATGKAWFKVPEA 159 Query: 378 IRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIE 557 I+FVL G + ++ KD+IL IIG+I V GA Y+SMEF G+ I++L++++R T+ NM IE Sbjct: 160 IKFVLKGNLGKWVSGKDVILYIIGKIGVDGALYKSMEFTGN-IKALSIDDRFTIANMAIE 218 Query: 558 AGGKNGVVPADETTFKY 608 AG KNG+ DE T Y Sbjct: 219 AGAKNGIFDFDEITEAY 235 Score = 20.8 bits (42), Expect(2) = 8e-33 Identities = 5/14 (35%), Positives = 11/14 (78%) Frame = +1 Query: 40 KVVIIPDHYIFTAD 81 K+ ++PDH++ + D Sbjct: 58 KIALVPDHFVPSKD 71
>LEU22_ARCFU (O28084) 3-isopropylmalate dehydratase large subunit 2 (EC| 4.2.1.33) (Isopropylmalate isomerase 2) (Alpha-IPM isomerase 2) (IPMI 2) Length = 416 Score = 139 bits (349), Expect = 8e-33 Identities = 67/160 (41%), Positives = 103/160 (64%) Frame = +3 Query: 129 EQKIKYFYDIKDLSDFRANPDYKGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFAT 308 +QK Y + K +DF NP +G+ H + E + +PG++ +G DSHTC G G F+T Sbjct: 76 DQKFIYEFAKKVGADF--NPPGEGIIHQIMV-ERYVKPGDLAVGADSHTCTYGGIGAFST 132 Query: 309 GIGNTDAGFVMGTGKALLKVPPTIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSME 488 G+G+TD + GK +VP + R LDG +P + AKD+IL++IG++ V GATY+++E Sbjct: 133 GMGSTDVAVAIALGKNWFRVPESFRVQLDGSLPKGVFAKDVILKLIGDLGVDGATYKALE 192 Query: 489 FVGSTIESLTMEERMTLCNMVIEAGGKNGVVPADETTFKY 608 F G E++T+EER+T+ NM +E G K G+ +DE T K+ Sbjct: 193 FHGECAENMTVEERLTIANMAVECGAKAGIFESDENTRKF 232
>LEU22_THEMA (Q9WZ24) 3-isopropylmalate dehydratase large subunit 2 (EC| 4.2.1.33) (Isopropylmalate isomerase 2) (Alpha-IPM isomerase 2) (IPMI 2) Length = 417 Score = 133 bits (334), Expect = 5e-31 Identities = 68/164 (41%), Positives = 103/164 (62%), Gaps = 1/164 (0%) Frame = +3 Query: 120 FCQEQKIKYFYDIKDLSDFRANPDYKGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQ 299 F +EQ I+ F++I + G+ H+ L +EG + G++++G DSHTC GA G Sbjct: 82 FAREQGIEKFFEIGRM----------GIEHVLLPEEGIVKSGDLVVGADSHTCTYGALGA 131 Query: 300 FATGIGNTD-AGFVMGTGKALLKVPPTIRFVLDGEMPPYLLAKDLILQIIGEISVSGATY 476 FATG+G+TD AGF + GK +VP +I+ L G+ + AKDL+L++I + V GA Y Sbjct: 132 FATGVGSTDIAGFYL-IGKVWFRVPESIKVTLRGKFKDLVTAKDLVLKLISILGVDGANY 190 Query: 477 RSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGVVPADETTFKY 608 +++EF G ++ ++M+ R T+ NM IEAGGK G+ P DE T Y Sbjct: 191 KAIEFSGPGVKEISMDGRFTISNMAIEAGGKTGLFPVDEITIAY 234
>LEU21_THEMA (Q9WYC7) 3-isopropylmalate dehydratase large subunit 1 (EC| 4.2.1.33) (Isopropylmalate isomerase 1) (Alpha-IPM isomerase 1) (IPMI 1) Length = 418 Score = 130 bits (327), Expect = 3e-30 Identities = 59/137 (43%), Positives = 95/137 (69%) Frame = +3 Query: 198 GVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFATGIGNTDAGFVMGTGKALLKVPPT 377 G+ H LA++ + +PG+++ G DSHTC AG G F TG+G+TD + G G+ KVP T Sbjct: 97 GISHQILAEK-YVKPGDLVAGADSHTCTAGGLGAFGTGMGSTDVAIIFGLGQNWFKVPET 155 Query: 378 IRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIE 557 I+ V++G++ + AKD+IL+I + GATY+++EF GS IE++ +E+R+T+ NM +E Sbjct: 156 IKVVVNGKLQDGVYAKDIILEIARILGSDGATYKALEFHGSCIENMNVEDRLTISNMAVE 215 Query: 558 AGGKNGVVPADETTFKY 608 G K G++P+DE T ++ Sbjct: 216 VGAKAGLMPSDEKTREF 232
>LEU21_METJA (Q58409) 3-isopropylmalate dehydratase large subunit 1 (EC| 4.2.1.33) (Isopropylmalate isomerase 1) (Alpha-IPM isomerase 1) (IPMI 1) Length = 420 Score = 129 bits (323), Expect = 9e-30 Identities = 64/138 (46%), Positives = 90/138 (65%) Frame = +3 Query: 195 KGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFATGIGNTDAGFVMGTGKALLKVPP 374 +G+CH LA E + P + G DSHTC GAFG FATG G TD ++ TG+ +KVP Sbjct: 95 EGICHQILA-ENYVLPNMFVAGGDSHTCTHGAFGAFATGFGATDMAYIYATGETWIKVPK 153 Query: 375 TIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVI 554 TIR + G+ + AKD++L++ EI GATY ++E+ G ++++ M+ R+TLCNM I Sbjct: 154 TIRVDIVGKNEN-VSAKDIVLRVCKEIGRRGATYMAIEYGGEVVKNMDMDGRLTLCNMAI 212 Query: 555 EAGGKNGVVPADETTFKY 608 E GGK GV+ ADE T+ Y Sbjct: 213 EMGGKTGVIEADEITYDY 230
>LEU2_RHOBA (Q7UIA7) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 485 Score = 124 bits (311), Expect = 2e-28 Identities = 65/162 (40%), Positives = 95/162 (58%) Frame = +3 Query: 123 CQEQKIKYFYDIKDLSDFRANPDYKGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQF 302 C+E ++ F D+ D R +G+ H+ + G+ +PG ++ DSHT GAFG Sbjct: 109 CKEFGVQLF----DIDDVR-----QGIVHVIGPENGYTQPGMTIVCGDSHTATHGAFGSL 159 Query: 303 ATGIGNTDAGFVMGTGKALLKVPPTIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRS 482 A GIG ++ V+ T L P T +DGE+ + AKD+IL +IG+I +G T Sbjct: 160 AFGIGTSEVEHVLATQTLLQFKPKTFELRVDGELARGVTAKDMILYLIGQIGTAGGTGYV 219 Query: 483 MEFVGSTIESLTMEERMTLCNMVIEAGGKNGVVPADETTFKY 608 +EF G + +LTMEERMT+CNM IEAG + G++ D+TTF Y Sbjct: 220 LEFTGDAVRNLTMEERMTVCNMSIEAGARAGMIAPDQTTFDY 261
>LEU2_RHIME (Q92L76) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 469 Score = 124 bits (311), Expect = 2e-28 Identities = 62/145 (42%), Positives = 87/145 (60%) Frame = +3 Query: 174 FRANPDYKGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFATGIGNTDAGFVMGTGK 353 + N +G+ HI ++G PG ++ DSHT GAFG A GIG ++ V+ T Sbjct: 101 YSENDKRQGIVHIVGPEQGFTLPGMTIVCGDSHTSTHGAFGALAHGIGTSEVEHVLATQT 160 Query: 354 ALLKVPPTIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERM 533 + K + +DG++PP + AKD+IL IIGEI +G T +EF G I SL+ME RM Sbjct: 161 LIQKKAKNMLVRVDGQLPPGVTAKDIILAIIGEIGTAGGTGHVIEFAGEAIRSLSMEGRM 220 Query: 534 TLCNMVIEAGGKNGVVPADETTFKY 608 T+CNM IE G + G++ DETTF+Y Sbjct: 221 TVCNMTIEGGARAGLIAPDETTFEY 245
>LEU2_CANMA (Q00464) 3-isopropylmalate dehydratase (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 770 Score = 124 bits (311), Expect = 2e-28 Identities = 63/160 (39%), Positives = 93/160 (58%) Frame = +3 Query: 129 EQKIKYFYDIKDLSDFRANPDYKGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFAT 308 EQ +K F D++ F D +G+ H+ ++G PG ++ DSHT GAFG A Sbjct: 94 EQNVKDF----DVTYFGMTDDRQGIVHVVGPEQGFTLPGTTVVCGDSHTSTHGAFGALAF 149 Query: 309 GIGNTDAGFVMGTGKALLKVPPTIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSME 488 GIG ++ V+ T + P +R +DGE+ + +KDL+L +IG I +G T +E Sbjct: 150 GIGTSEVEHVLATQTTIQANPKNMRITIDGELSEGITSKDLVLHVIGVIGTAGGTGCVIE 209 Query: 489 FVGSTIESLTMEERMTLCNMVIEAGGKNGVVPADETTFKY 608 F G IE L+ME RM++CNM IEAG + G++ DE TF+Y Sbjct: 210 FAGKAIEDLSMEARMSICNMAIEAGARAGMIKPDEKTFEY 249
>LEU2_NITEU (Q82WI9) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 470 Score = 124 bits (310), Expect = 3e-28 Identities = 62/148 (41%), Positives = 92/148 (62%) Frame = +3 Query: 165 LSDFRANPDYKGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFATGIGNTDAGFVMG 344 +++FR N + +G+ H+ ++G PG ++ DSHT GAF A GIG ++ V+ Sbjct: 97 ITEFRMNDERQGIVHVIGPEQGATLPGMTVVCGDSHTSTHGAFACLAFGIGTSEVEHVLA 156 Query: 345 TGKALLKVPPTIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTME 524 T + + T+ ++G++PP + AKD+ L +IGEI +G T ++EF GS I SL+ME Sbjct: 157 TQCLVARKSKTMLVRVEGDLPPGVTAKDIALAVIGEIGTAGGTGYAIEFAGSAIRSLSME 216 Query: 525 ERMTLCNMVIEAGGKNGVVPADETTFKY 608 RMTLCNM IEAG + G+V ADE T Y Sbjct: 217 GRMTLCNMAIEAGARAGMVGADEVTIDY 244
>LEU2_BURMA (Q62AI6) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 469 Score = 122 bits (306), Expect = 8e-28 Identities = 63/152 (41%), Positives = 92/152 (60%) Frame = +3 Query: 153 DIKDLSDFRANPDYKGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFATGIGNTDAG 332 D ++ F+ N +G+ HI ++G PG ++ DSHT GAFG A GIG ++ Sbjct: 91 DAYGITQFKMNDVRQGIVHIIGPEQGATLPGMTIVCGDSHTSTHGAFGALAHGIGTSEVE 150 Query: 333 FVMGTGKALLKVPPTIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIES 512 V+ T L K + ++G++P AKD++L IIG+I +G T ++EF GSTI + Sbjct: 151 HVLATQTLLQKKSKNMLVKVEGQLPRGCTAKDIVLAIIGQIGTAGGTGYAIEFGGSTIRA 210 Query: 513 LTMEERMTLCNMVIEAGGKNGVVPADETTFKY 608 LTME RMT+CNM IEAG + G+V D+TT +Y Sbjct: 211 LTMEGRMTVCNMAIEAGARAGMVAVDDTTVEY 242
>LEU2_BURPS (Q63JK9) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 469 Score = 121 bits (304), Expect = 1e-27 Identities = 63/152 (41%), Positives = 91/152 (59%) Frame = +3 Query: 153 DIKDLSDFRANPDYKGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFATGIGNTDAG 332 D ++ F+ N +G+ HI ++G PG ++ DSHT GAFG A GIG ++ Sbjct: 91 DAYGITQFKMNDVRQGIVHIIGPEQGATLPGMTIVCGDSHTSTHGAFGALAHGIGTSEVE 150 Query: 333 FVMGTGKALLKVPPTIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIES 512 V+ T L K + ++G++P AKD++L IIG I +G T ++EF GSTI + Sbjct: 151 HVLATQTLLQKKSKNMLVKVEGQLPRGCTAKDIVLAIIGRIGTAGGTGYAIEFGGSTIRA 210 Query: 513 LTMEERMTLCNMVIEAGGKNGVVPADETTFKY 608 LTME RMT+CNM IEAG + G+V D+TT +Y Sbjct: 211 LTMEGRMTVCNMAIEAGARAGMVAVDDTTVEY 242
>LEU2_LEPIN (Q8F4E6) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 465 Score = 121 bits (303), Expect = 2e-27 Identities = 67/162 (41%), Positives = 97/162 (59%) Frame = +3 Query: 123 CQEQKIKYFYDIKDLSDFRANPDYKGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQF 302 C E I+ + DF+ NPD +G+ H+ + G PG ++ DSHT GAFG Sbjct: 89 CDENGIRVY-------DFQ-NPD-QGIIHVIAPEMGLTHPGMTIVCGDSHTSTHGAFGAL 139 Query: 303 ATGIGNTDAGFVMGTGKALLKVPPTIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRS 482 A GIG ++ V+ T + K T+ +DG++ + AKD+IL IIG+I +GAT Sbjct: 140 AFGIGTSEVEHVLATQTLVQKRAKTMEIRVDGKLSDKVTAKDIILAIIGKIGTAGATGYV 199 Query: 483 MEFVGSTIESLTMEERMTLCNMVIEAGGKNGVVPADETTFKY 608 +E+ GS I++L+ME RMT+CNM IEAG + G++ DETTF Y Sbjct: 200 IEYRGSAIQALSMEARMTICNMSIEAGARAGLIAPDETTFNY 241
>LEU2_LEPIC (Q72RC4) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 465 Score = 121 bits (303), Expect = 2e-27 Identities = 67/162 (41%), Positives = 97/162 (59%) Frame = +3 Query: 123 CQEQKIKYFYDIKDLSDFRANPDYKGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQF 302 C E I+ + DF+ NPD +G+ H+ + G PG ++ DSHT GAFG Sbjct: 89 CDENGIRVY-------DFQ-NPD-QGIIHVIAPEMGLTHPGMTIVCGDSHTSTHGAFGAL 139 Query: 303 ATGIGNTDAGFVMGTGKALLKVPPTIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRS 482 A GIG ++ V+ T + K T+ +DG++ + AKD+IL IIG+I +GAT Sbjct: 140 AFGIGTSEVEHVLATQTLVQKRAKTMEIRVDGKLSDKVTAKDIILAIIGKIGTAGATGYV 199 Query: 483 MEFVGSTIESLTMEERMTLCNMVIEAGGKNGVVPADETTFKY 608 +E+ GS I++L+ME RMT+CNM IEAG + G++ DETTF Y Sbjct: 200 IEYRGSAIQALSMEARMTICNMSIEAGARAGLIAPDETTFNY 241
>LEU2_NITOC (Q3J716) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 469 Score = 120 bits (300), Expect = 4e-27 Identities = 63/148 (42%), Positives = 88/148 (59%) Frame = +3 Query: 165 LSDFRANPDYKGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFATGIGNTDAGFVMG 344 L++FR + +G+ HI ++G PG ++ DSHT GAFG A GIG ++ V+ Sbjct: 96 LTEFRMDDPRQGIVHIVGPEQGATLPGMTVVCGDSHTATHGAFGALAFGIGTSEVEHVLA 155 Query: 345 TGKALLKVPPTIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTME 524 T L K + + G++ P + +KDLIL II I +G T ++EF G TI +L+ME Sbjct: 156 TQCLLQKKSKNMLIQVSGKLAPGVYSKDLILAIIARIGTAGGTGYTIEFAGETIRALSME 215 Query: 525 ERMTLCNMVIEAGGKNGVVPADETTFKY 608 RMTLCNM IEAG + G+V DETT Y Sbjct: 216 GRMTLCNMAIEAGARAGLVAVDETTIDY 243
>LEU2_AGRT5 (Q8UBY9) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 469 Score = 119 bits (298), Expect = 7e-27 Identities = 60/138 (43%), Positives = 83/138 (60%) Frame = +3 Query: 195 KGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFATGIGNTDAGFVMGTGKALLKVPP 374 +G+ HI ++G PG ++ DSHT GAFG A GIG ++ V+ T + K Sbjct: 108 QGIVHIVGPEQGFTLPGMTIVCGDSHTSTHGAFGALAHGIGTSEVEHVLATQTLIQKKAK 167 Query: 375 TIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVI 554 + +DG++P + AKD+IL IIGEI +G T +EF G I SL+ME RMT+CNM I Sbjct: 168 NMLVRVDGKLPESVTAKDIILAIIGEIGTAGGTGHVIEFAGEAIRSLSMEGRMTVCNMTI 227 Query: 555 EAGGKNGVVPADETTFKY 608 E G + G++ DETTF Y Sbjct: 228 EGGARAGLIAPDETTFDY 245
>LEU2_STRAW (Q82JR8) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 477 Score = 118 bits (296), Expect = 1e-26 Identities = 63/138 (45%), Positives = 81/138 (58%) Frame = +3 Query: 195 KGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFATGIGNTDAGFVMGTGKALLKVPP 374 +GV H+ Q G +PG ++ DSHT GAFG A GIG + V+ T L P Sbjct: 105 QGVVHVVGPQLGLTQPGTTVVCGDSHTSTHGAFGALAFGIGTSQVEHVLATQTLPLARPK 164 Query: 375 TIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVI 554 T+ +DGE+P + AKDLIL II I G +E+ GS IE L+ME RMT+CNM I Sbjct: 165 TMAITVDGELPDGVTAKDLILAIIARIGTGGGQGYILEYRGSAIEKLSMEARMTICNMSI 224 Query: 555 EAGGKNGVVPADETTFKY 608 EAG + G++ DETTF Y Sbjct: 225 EAGARAGMIAPDETTFAY 242
>LEU2_ASHGO (Q74ZM9) 3-isopropylmalate dehydratase (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 776 Score = 118 bits (296), Expect = 1e-26 Identities = 65/161 (40%), Positives = 93/161 (57%), Gaps = 1/161 (0%) Frame = +3 Query: 129 EQKIKYFY-DIKDLSDFRANPDYKGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFA 305 EQ +K F+ +SD R +G+ HI ++G PG ++ DSHT GAFG A Sbjct: 97 EQNVKDFHVPYLGMSDER-----QGIVHIIGPEQGFTLPGTTVVCGDSHTSTHGAFGALA 151 Query: 306 TGIGNTDAGFVMGTGKALLKVPPTIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSM 485 GIG ++ V+ T + +R ++G + P + +KDLIL IIG I +G T + Sbjct: 152 FGIGTSEVEHVLATQTVMQSKSKNMRIHVEGSLSPGITSKDLILHIIGVIGTAGGTGCVI 211 Query: 486 EFVGSTIESLTMEERMTLCNMVIEAGGKNGVVPADETTFKY 608 EF G I+ LTME RM++CNM IEAG + G++ DETTF+Y Sbjct: 212 EFTGQAIQELTMEARMSMCNMAIEAGARAGMIQPDETTFEY 252
>LEU2_PICTO (Q6L0K5) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 413 Score = 118 bits (295), Expect(2) = 1e-26 Identities = 58/137 (42%), Positives = 79/137 (57%) Frame = +3 Query: 198 GVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFATGIGNTDAGFVMGTGKALLKVPPT 377 GVCH + ++G PG ++ G DSHT GA + GIG+T+AG + GTG+ KVP T Sbjct: 96 GVCHQVMMEKGFAAPGRLIAGADSHTNTYGALSCVSVGIGSTEAGVIFGTGRMWFKVPET 155 Query: 378 IRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIE 557 ++G + KD+IL ++ I G+ Y+ MEF GSTI+ L + ERMT+ NM E Sbjct: 156 DLIRINGRPKKGVYGKDIILNVLSRIGNGGSAYKCMEFTGSTIDYLDINERMTMANMTTE 215 Query: 558 AGGKNGVVPADETTFKY 608 AG K ADE T Y Sbjct: 216 AGAKCSFFNADEKTLDY 232 Score = 21.2 bits (43), Expect(2) = 1e-26 Identities = 5/10 (50%), Positives = 10/10 (100%) Frame = +1 Query: 40 KVVIIPDHYI 69 ++V+IPDH++ Sbjct: 55 RIVVIPDHFV 64
>LEU2_PELUB (Q4FP15) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 467 Score = 118 bits (295), Expect = 2e-26 Identities = 58/142 (40%), Positives = 88/142 (61%) Frame = +3 Query: 183 NPDYKGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFATGIGNTDAGFVMGTGKALL 362 N +G+ HI ++G +PG V++ DSHT GAFG A GIG ++ V+ T + Sbjct: 101 NDKRQGIVHIIGPEQGFTQPGTVIVCGDSHTATHGAFGALAFGIGTSEVEHVLATQTLVQ 160 Query: 363 KVPPTIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLC 542 K R ++G++P + +KD+ILQIIG+I +G T +E+ GS I SL++E+RMT+C Sbjct: 161 KKAKNFRINVNGKLPIGVTSKDVILQIIGQIGTAGGTGSVIEYAGSLISSLSVEQRMTIC 220 Query: 543 NMVIEAGGKNGVVPADETTFKY 608 NM IE G + G++ DE F+Y Sbjct: 221 NMTIEGGARAGLIAPDEKIFEY 242
>LEU2_RHILO (Q98EF1) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 469 Score = 118 bits (295), Expect = 2e-26 Identities = 65/166 (39%), Positives = 94/166 (56%), Gaps = 5/166 (3%) Frame = +3 Query: 126 QEQKIKYFYDIKDLSDFRA-----NPDYKGVCHIALAQEGHCRPGEVLLGTDSHTCNAGA 290 +E +I+ K+ DF N +G+ HI ++G PG ++ DSHT GA Sbjct: 80 EESRIQVEALAKNAKDFGVEYYSENDIRQGIVHIIGPEQGFTLPGMTIVCGDSHTSTHGA 139 Query: 291 FGQFATGIGNTDAGFVMGTGKALLKVPPTIRFVLDGEMPPYLLAKDLILQIIGEISVSGA 470 FG A GIG ++ V+ T + + + +DG++P + AKD+IL IIGEI +G Sbjct: 140 FGALAHGIGTSEVEHVLATQTLIQRKAKNMLVRVDGQLPEGVTAKDIILAIIGEIGTAGG 199 Query: 471 TYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGVVPADETTFKY 608 T +E+ G I SL+ME RMT+CNM IE G + G++ ADETTF Y Sbjct: 200 TGYVIEYAGEAIRSLSMEGRMTICNMSIEGGARAGLIAADETTFAY 245
>LEU2_BORPE (Q7VY75) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 467 Score = 117 bits (294), Expect = 2e-26 Identities = 59/148 (39%), Positives = 91/148 (61%) Frame = +3 Query: 165 LSDFRANPDYKGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFATGIGNTDAGFVMG 344 +++FR N +G+ H+ ++G PG ++ DSHT GA G A GIG ++ V+ Sbjct: 95 ITEFRMNDLRQGIVHVIGPEQGATLPGMTVVCGDSHTSTHGALGALAFGIGTSEVEHVLA 154 Query: 345 TGKALLKVPPTIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTME 524 T L+K +++ ++GE+P AKD++L IIG I +G T ++EF GSTI L++E Sbjct: 155 TQTLLMKKAKSMQINVEGELPFGCTAKDVVLHIIGIIGTAGGTGHAIEFSGSTIRGLSVE 214 Query: 525 ERMTLCNMVIEAGGKNGVVPADETTFKY 608 RMT+CNM IEAG ++G+V D+ T Y Sbjct: 215 GRMTVCNMAIEAGARSGMVAVDDKTIDY 242
>LEU2_BORPA (Q7W931) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 467 Score = 117 bits (294), Expect = 2e-26 Identities = 59/148 (39%), Positives = 91/148 (61%) Frame = +3 Query: 165 LSDFRANPDYKGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFATGIGNTDAGFVMG 344 +++FR N +G+ H+ ++G PG ++ DSHT GA G A GIG ++ V+ Sbjct: 95 ITEFRMNDLRQGIVHVIGPEQGATLPGMTVVCGDSHTSTHGALGALAFGIGTSEVEHVLA 154 Query: 345 TGKALLKVPPTIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTME 524 T L+K +++ ++GE+P AKD++L IIG I +G T ++EF GSTI L++E Sbjct: 155 TQTLLMKKAKSMQINVEGELPFGCTAKDVVLHIIGIIGTAGGTGHAIEFSGSTIRGLSVE 214 Query: 525 ERMTLCNMVIEAGGKNGVVPADETTFKY 608 RMT+CNM IEAG ++G+V D+ T Y Sbjct: 215 GRMTVCNMAIEAGARSGMVAVDDKTIDY 242
>LEU2_BORBR (Q7WKH6) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 467 Score = 117 bits (294), Expect = 2e-26 Identities = 59/148 (39%), Positives = 91/148 (61%) Frame = +3 Query: 165 LSDFRANPDYKGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFATGIGNTDAGFVMG 344 +++FR N +G+ H+ ++G PG ++ DSHT GA G A GIG ++ V+ Sbjct: 95 ITEFRMNDLRQGIVHVIGPEQGATLPGMTVVCGDSHTSTHGALGALAFGIGTSEVEHVLA 154 Query: 345 TGKALLKVPPTIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTME 524 T L+K +++ ++GE+P AKD++L IIG I +G T ++EF GSTI L++E Sbjct: 155 TQTLLMKKAKSMQINVEGELPFGCTAKDVVLHIIGIIGTAGGTGHAIEFSGSTIRGLSVE 214 Query: 525 ERMTLCNMVIEAGGKNGVVPADETTFKY 608 RMT+CNM IEAG ++G+V D+ T Y Sbjct: 215 GRMTVCNMAIEAGARSGMVAVDDKTIDY 242
>LEU2_SCHPO (O14289) 3-isopropylmalate dehydratase (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 758 Score = 117 bits (294), Expect = 2e-26 Identities = 64/160 (40%), Positives = 92/160 (57%) Frame = +3 Query: 129 EQKIKYFYDIKDLSDFRANPDYKGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFAT 308 E IK F L+ + N +G+ H+ ++G PG L+ DSHT GAFG A Sbjct: 99 ENNIKEF----GLTYYGMNDRRQGIVHVIGPEQGFTLPGTTLVCGDSHTSTHGAFGALAF 154 Query: 309 GIGNTDAGFVMGTGKALLKVPPTIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSME 488 GIG ++ V+ T L + +R ++G++P + +KDLIL IIG I +G T +E Sbjct: 155 GIGTSEVEHVLATQTILQRKSKNMRIRVNGKLPEGIASKDLILHIIGVIGTAGGTGSVIE 214 Query: 489 FVGSTIESLTMEERMTLCNMVIEAGGKNGVVPADETTFKY 608 F G IE L+ME RM++CNM IEAG + G++ D TTF+Y Sbjct: 215 FCGEAIEGLSMEARMSMCNMSIEAGARAGMIAPDATTFEY 254
>LEU2_BUCUS (Q9EVI3) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) (Fragment) Length = 442 Score = 117 bits (293), Expect = 3e-26 Identities = 65/162 (40%), Positives = 95/162 (58%) Frame = +3 Query: 123 CQEQKIKYFYDIKDLSDFRANPDYKGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQF 302 CQE I YDI NP+ +G+ H+ ++G PG ++ DSHT GAFG Sbjct: 90 CQEFNIP-LYDIN-------NPN-QGIVHVIAPEKGMTLPGMTIVCGDSHTSTHGAFGAL 140 Query: 303 ATGIGNTDAGFVMGTGKALLKVPPTIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRS 482 A GIG ++ V+ T K ++ + GE+P ++ AKD+IL IIG++ S T Sbjct: 141 AFGIGTSEVEHVLATQTLKQKRFKNMKIEIIGEIPKFVTAKDIILFIIGKLGSSSGTGYV 200 Query: 483 MEFVGSTIESLTMEERMTLCNMVIEAGGKNGVVPADETTFKY 608 +EF G I++++MEERMT+CNM IE G K+G++ DE T+KY Sbjct: 201 IEFCGDVIKNMSMEERMTICNMAIEMGAKSGLIAPDEITYKY 242
>LEU2_USTMA (P49601) 3-isopropylmalate dehydratase (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 773 Score = 117 bits (292), Expect = 3e-26 Identities = 63/160 (39%), Positives = 94/160 (58%) Frame = +3 Query: 129 EQKIKYFYDIKDLSDFRANPDYKGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFAT 308 E+ +K F L+ F + + +G+ HI ++G PG ++ DSHT GAFG A Sbjct: 94 EENVKAF----GLTFFGLSDNRQGIVHIIGPEQGFTLPGATIVCGDSHTSTHGAFGALAF 149 Query: 309 GIGNTDAGFVMGTGKALLKVPPTIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSME 488 GIG ++ V+ T L K + +DGE+ + +KD+IL IIG I +G T +E Sbjct: 150 GIGTSEVEHVLATQTLLQKRAKNMLIQVDGELSQGVTSKDIILHIIGLIGTAGGTGHVIE 209 Query: 489 FVGSTIESLTMEERMTLCNMVIEAGGKNGVVPADETTFKY 608 + GSTI SL+ME RM++CNM IEAG + G++ DE T++Y Sbjct: 210 YAGSTIRSLSMEARMSICNMSIEAGARAGLIAPDEITYEY 249
>LEU2_SYMTH (Q67MJ2) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 481 Score = 117 bits (292), Expect = 3e-26 Identities = 60/139 (43%), Positives = 84/139 (60%) Frame = +3 Query: 192 YKGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFATGIGNTDAGFVMGTGKALLKVP 371 ++G+ H+ + G +PG ++ DSHT GAFG A GIG ++ V+ T P Sbjct: 112 FQGIVHVIGPELGLTQPGLTIVCGDSHTATHGAFGALAFGIGTSEVEHVLATQCLWQHKP 171 Query: 372 PTIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMV 551 + ++G++PP AKDLIL IIG+I GAT +E+ G I SL+ME RMT+CNM Sbjct: 172 KVMEIRVNGKLPPGTTAKDLILGIIGQIGTDGATGYVIEYTGEAIRSLSMEGRMTVCNMS 231 Query: 552 IEAGGKNGVVPADETTFKY 608 IEAG + G++ DETTF Y Sbjct: 232 IEAGARAGMIAPDETTFAY 250
>LEU2_STAS1 (Q49Z14) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 456 Score = 117 bits (292), Expect = 3e-26 Identities = 59/145 (40%), Positives = 86/145 (59%) Frame = +3 Query: 174 FRANPDYKGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFATGIGNTDAGFVMGTGK 353 F D +G+ H+ + G +PG+ ++ DSHT GAFG A GIG ++ V T Sbjct: 97 FDMGSDEQGIVHMVGPETGLTQPGKTIVCGDSHTATHGAFGAIAFGIGTSEVEHVFATQS 156 Query: 354 ALLKVPPTIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERM 533 P ++ ++G++P + AKD+IL +I + V T ++EF G TI SL+ME RM Sbjct: 157 LWQTKPKNLKIEVNGKLPTGVYAKDIILHLINQHGVDFGTGYALEFSGETIRSLSMEARM 216 Query: 534 TLCNMVIEAGGKNGVVPADETTFKY 608 T+CNM IEAG K G++ DETTF+Y Sbjct: 217 TICNMAIEAGAKYGMMAPDETTFEY 241
>LEU2_BUCTS (O31293) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 466 Score = 117 bits (292), Expect = 3e-26 Identities = 63/162 (38%), Positives = 95/162 (58%) Frame = +3 Query: 123 CQEQKIKYFYDIKDLSDFRANPDYKGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQF 302 C++ IK YD+ ++ +G+ H+ ++G PG ++ DSHT GAFG Sbjct: 90 CKDFNIK-LYDLNHIN--------QGIVHVMGPEQGLTLPGMTIVCGDSHTSTHGAFGTL 140 Query: 303 ATGIGNTDAGFVMGTGKALLKVPPTIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRS 482 A GIG ++ V+ T T++ ++G + PY+ AKD+IL II ++ + T Sbjct: 141 AFGIGTSEVEHVLATQTLKQARSKTMKIGINGILKPYITAKDVILYIIKKVGTAFGTGYV 200 Query: 483 MEFVGSTIESLTMEERMTLCNMVIEAGGKNGVVPADETTFKY 608 +EF G TIE+LTME RMT+CNMVIE G K+G++ D TT+KY Sbjct: 201 VEFSGETIENLTMEGRMTICNMVIEMGAKSGIIAPDATTYKY 242
>LEU2_STRCO (O86534) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 476 Score = 117 bits (292), Expect = 3e-26 Identities = 62/138 (44%), Positives = 80/138 (57%) Frame = +3 Query: 195 KGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFATGIGNTDAGFVMGTGKALLKVPP 374 +GV H+ Q G +PG ++ DSHT GAFG A GIG + V+ T L P Sbjct: 105 QGVVHVVGPQLGLTQPGTTVVCGDSHTSTHGAFGALAFGIGTSQVEHVLATQTLPLARPK 164 Query: 375 TIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVI 554 T+ +DGE+P + AKDLIL II I G +E+ G IE L+ME RMT+CNM I Sbjct: 165 TMAITVDGELPEGVTAKDLILAIIARIGTGGGQGYILEYRGEAIEKLSMEARMTICNMSI 224 Query: 555 EAGGKNGVVPADETTFKY 608 EAG + G++ DETTF Y Sbjct: 225 EAGARAGMIAPDETTFAY 242
>LEU2_BRUSU (Q8FYG9) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 469 Score = 117 bits (292), Expect = 3e-26 Identities = 58/138 (42%), Positives = 84/138 (60%) Frame = +3 Query: 195 KGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFATGIGNTDAGFVMGTGKALLKVPP 374 +G+ HI ++G PG ++ DSHT GAFG A GIG ++ V+ T + K Sbjct: 108 QGIVHIVGPEQGFTLPGMTIVCGDSHTSTHGAFGALAHGIGTSEVEHVLATQTLIQKKAK 167 Query: 375 TIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVI 554 + +DG++P + AKD++L IIGEI +G T +E+ G I SL+ME RMT+CNM I Sbjct: 168 NMLVRVDGKLPAGVTAKDIVLAIIGEIGTAGGTGYVIEYAGEAIRSLSMEGRMTICNMSI 227 Query: 555 EAGGKNGVVPADETTFKY 608 E G + G++ DETTF+Y Sbjct: 228 EGGARAGLIAPDETTFEY 245
>LEU2_BRUME (Q8YJC9) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 469 Score = 117 bits (292), Expect = 3e-26 Identities = 58/138 (42%), Positives = 84/138 (60%) Frame = +3 Query: 195 KGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFATGIGNTDAGFVMGTGKALLKVPP 374 +G+ HI ++G PG ++ DSHT GAFG A GIG ++ V+ T + K Sbjct: 108 QGIVHIVGPEQGFTLPGMTIVCGDSHTSTHGAFGALAHGIGTSEVEHVLATQTLIQKKAK 167 Query: 375 TIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVI 554 + +DG++P + AKD++L IIGEI +G T +E+ G I SL+ME RMT+CNM I Sbjct: 168 NMLVRVDGKLPAGVTAKDIVLAIIGEIGTAGGTGYVIEYAGEAIRSLSMEGRMTICNMSI 227 Query: 555 EAGGKNGVVPADETTFKY 608 E G + G++ DETTF+Y Sbjct: 228 EGGARAGLIAPDETTFEY 245
>LEU2_PSEPK (Q88LE8) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 477 Score = 116 bits (291), Expect = 4e-26 Identities = 60/161 (37%), Positives = 92/161 (57%) Frame = +3 Query: 126 QEQKIKYFYDIKDLSDFRANPDYKGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFA 305 Q Q + D + +F+ N + +G+ H+ ++G PG ++ DSHT GAFG A Sbjct: 87 QVQTLDENCDEYGIVEFKMNDERQGIVHVISPEQGATLPGMTVVCGDSHTSTHGAFGALA 146 Query: 306 TGIGNTDAGFVMGTGKALLKVPPTIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSM 485 GIG ++ V+ T + K + ++G++P + AKD++L +IG+I +G +M Sbjct: 147 HGIGTSEVEHVLATQCLVAKKMKNMLVRVEGQLPAGVTAKDIVLAVIGKIGTAGGNGHAM 206 Query: 486 EFVGSTIESLTMEERMTLCNMVIEAGGKNGVVPADETTFKY 608 EF GS I L+ME RMT+CNM IEAG + G+V D TT Y Sbjct: 207 EFAGSAIRELSMEGRMTICNMSIEAGARVGLVATDATTVAY 247
>LEU2_RALEJ (Q46YV7) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 469 Score = 116 bits (291), Expect = 4e-26 Identities = 59/148 (39%), Positives = 87/148 (58%) Frame = +3 Query: 165 LSDFRANPDYKGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFATGIGNTDAGFVMG 344 ++ F+ N +G+ H+ ++G PG ++ DSHT GAFG A GIG ++ V+ Sbjct: 95 ITQFKMNDHRQGIVHVIGPEQGATLPGMTVVCGDSHTSTHGAFGALAHGIGTSEVEHVLA 154 Query: 345 TGKALLKVPPTIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTME 524 T L K + ++G++P AKD++L IIG+I +G T ++EF GS I LTME Sbjct: 155 TQTLLGKKAKNMLVKVEGKLPRGCTAKDIVLAIIGKIGTAGGTGYTIEFAGSAIRDLTME 214 Query: 525 ERMTLCNMVIEAGGKNGVVPADETTFKY 608 RMT+CNM IEAG + G+V D T +Y Sbjct: 215 GRMTVCNMAIEAGARAGLVAVDNVTLEY 242
>LEU2_STAES (Q8CNL1) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 456 Score = 116 bits (290), Expect = 6e-26 Identities = 58/145 (40%), Positives = 85/145 (58%) Frame = +3 Query: 174 FRANPDYKGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFATGIGNTDAGFVMGTGK 353 F D +G+ H+ + G +PG+ ++ DSHT GAFG A GIG ++ V T Sbjct: 97 FDMGSDEQGIVHMVGPETGLTQPGKTIVCGDSHTATHGAFGAIAFGIGTSEVEHVFATQT 156 Query: 354 ALLKVPPTIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERM 533 P ++ ++G +P + AKD+IL +I + V T ++EF G TI++L+ME RM Sbjct: 157 LWQTKPKNLKININGSLPAGVYAKDIILYLINQYGVDFGTGYALEFTGETIKNLSMEARM 216 Query: 534 TLCNMVIEAGGKNGVVPADETTFKY 608 T+CNM IEAG K G++ DETTF Y Sbjct: 217 TICNMAIEAGAKYGLMQPDETTFNY 241
>LEU2_STAEQ (Q5HMF7) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 456 Score = 116 bits (290), Expect = 6e-26 Identities = 58/145 (40%), Positives = 85/145 (58%) Frame = +3 Query: 174 FRANPDYKGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFATGIGNTDAGFVMGTGK 353 F D +G+ H+ + G +PG+ ++ DSHT GAFG A GIG ++ V T Sbjct: 97 FDMGSDEQGIVHMVGPETGLTQPGKTIVCGDSHTATHGAFGAIAFGIGTSEVEHVFATQT 156 Query: 354 ALLKVPPTIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERM 533 P ++ ++G +P + AKD+IL +I + V T ++EF G TI++L+ME RM Sbjct: 157 LWQTKPKNLKININGSLPAGVYAKDIILYLINQYGVDFGTGYALEFTGETIKNLSMEARM 216 Query: 534 TLCNMVIEAGGKNGVVPADETTFKY 608 T+CNM IEAG K G++ DETTF Y Sbjct: 217 TICNMAIEAGAKYGLMQPDETTFNY 241
>LEU2_YEAST (P07264) 3-isopropylmalate dehydratase (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 779 Score = 116 bits (290), Expect = 6e-26 Identities = 58/138 (42%), Positives = 84/138 (60%) Frame = +3 Query: 195 KGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFATGIGNTDAGFVMGTGKALLKVPP 374 +G+ H +EG PG ++ DSHT GAFG A GIG ++ V+ T + Sbjct: 118 QGIVHTIGPEEGFTLPGTTVVCGDSHTSTHGAFGSLAFGIGTSEVEHVLATQTIIQAKSK 177 Query: 375 TIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVI 554 +R ++G++ P + +KDLIL IIG I +G T +EF G IE+L+ME RM++CNM I Sbjct: 178 NMRITVNGKLSPGITSKDLILYIIGLIGTAGGTGCVIEFAGEAIEALSMEARMSMCNMAI 237 Query: 555 EAGGKNGVVPADETTFKY 608 EAG + G++ DETTF+Y Sbjct: 238 EAGARAGMIKPDETTFQY 255
>LEU2_NITWN (Q3SNV3) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 468 Score = 116 bits (290), Expect = 6e-26 Identities = 56/138 (40%), Positives = 85/138 (61%) Frame = +3 Query: 195 KGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFATGIGNTDAGFVMGTGKALLKVPP 374 +G+ H+ ++G PG ++ DSHT GAFG A GIG ++ V+ T + K Sbjct: 107 QGIVHVIGPEQGFTLPGTTIVCGDSHTSTHGAFGALAHGIGTSEVEHVLATQTLIQKKAK 166 Query: 375 TIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVI 554 +R V+DG++P + AKD+IL IIGEI +G T +E+ G I +L+ME RMT+CNM I Sbjct: 167 NMRAVVDGKLPDGVTAKDIILAIIGEIGTAGGTGYVLEYAGEAIRALSMEGRMTVCNMSI 226 Query: 555 EAGGKNGVVPADETTFKY 608 E G + G++ DET +++ Sbjct: 227 EGGARAGLIAPDETAYEF 244
>LEU2_RHIPU (P55251) 3-isopropylmalate dehydratase (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 755 Score = 115 bits (288), Expect = 1e-25 Identities = 62/160 (38%), Positives = 92/160 (57%) Frame = +3 Query: 129 EQKIKYFYDIKDLSDFRANPDYKGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFAT 308 E +K F L+ F + +G+ H+ ++G PG + DSHT GAFG A Sbjct: 93 EHNVKEF----GLTYFGMDDSRQGIVHVIGPEQGFTLPGCTVNCGDSHTSTHGAFGALAF 148 Query: 309 GIGNTDAGFVMGTGKALLKVPPTIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSME 488 GIG ++ V+ T L K +R +DG++ P + +KD++L IIG I +G T +E Sbjct: 149 GIGTSEVEHVLATQTLLQKKSKNMRVKVDGKLAPGVTSKDIVLHIIGVIGTAGGTGCVIE 208 Query: 489 FVGSTIESLTMEERMTLCNMVIEAGGKNGVVPADETTFKY 608 F GS E ++ME RM++CNM IEAG + G++ DETTF+Y Sbjct: 209 FCGSAFEQMSMEARMSVCNMSIEAGARAGMIAPDETTFEY 248
>LEU2_BUCUA (Q9EVG5) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) (Fragment) Length = 443 Score = 115 bits (287), Expect = 1e-25 Identities = 57/142 (40%), Positives = 88/142 (61%) Frame = +3 Query: 183 NPDYKGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFATGIGNTDAGFVMGTGKALL 362 NP+ +G+ H+ ++G PG ++ DSHT GAFG A GIG ++ V+ T Sbjct: 102 NPN-QGIVHVIAPEKGMTLPGMTIVCGDSHTSTHGAFGTLAFGIGTSEVEHVLATQTLKQ 160 Query: 363 KVPPTIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLC 542 K ++ + GEMP ++ AKD+IL IIG++ S +EF G+ I++++MEERMT+C Sbjct: 161 KRFKNMKVEIIGEMPKFVTAKDIILFIIGKLGSSSGAGHVIEFCGNVIKNMSMEERMTIC 220 Query: 543 NMVIEAGGKNGVVPADETTFKY 608 NM +E G K+G++ DE T+KY Sbjct: 221 NMAVEMGAKSGLIAPDEITYKY 242
>LEU2_SHISS (Q3Z5T8) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 466 Score = 115 bits (287), Expect = 1e-25 Identities = 59/142 (41%), Positives = 81/142 (57%) Frame = +3 Query: 183 NPDYKGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFATGIGNTDAGFVMGTGKALL 362 N Y+G+ H+ ++G PG ++ DSHT GAFG A GIG ++ V+ T Sbjct: 101 NHPYQGIVHVMGPEQGVTLPGMTIVCGDSHTATHGAFGALAFGIGTSEVEHVLATQTLKQ 160 Query: 363 KVPPTIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLC 542 T++ + G+ P + AKD++L IIG+ +G T +EF G I L+ME RMTLC Sbjct: 161 GRAKTMKIEVQGKAAPGITAKDIVLAIIGKTGSAGGTGHVVEFCGEAIRDLSMEGRMTLC 220 Query: 543 NMVIEAGGKNGVVPADETTFKY 608 NM IE G K G+V DETTF Y Sbjct: 221 NMAIEMGAKTGLVAPDETTFNY 242
>LEU2_BUCUN (Q9EVI6) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) (Fragment) Length = 443 Score = 114 bits (286), Expect = 2e-25 Identities = 62/162 (38%), Positives = 92/162 (56%) Frame = +3 Query: 123 CQEQKIKYFYDIKDLSDFRANPDYKGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQF 302 CQE I YDI N ++G+ H+ ++G PG ++ DSHT GAFG Sbjct: 90 CQEFNIP-LYDI--------NNPHQGIVHVIAPEKGMTLPGMTIVCGDSHTSTHGAFGAL 140 Query: 303 ATGIGNTDAGFVMGTGKALLKVPPTIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRS 482 A GIG ++ V+ T K ++ + G++P ++ AKD+IL IIG++ S T Sbjct: 141 AFGIGTSEVEHVLATQTLKQKRFKNMKIEIIGKIPRFVTAKDIILFIIGKLGSSSGTGHV 200 Query: 483 MEFVGSTIESLTMEERMTLCNMVIEAGGKNGVVPADETTFKY 608 +EF G I +++MEERMT+CNM IE G K+G++ DE T+ Y Sbjct: 201 IEFCGDVIRNMSMEERMTICNMAIEMGAKSGLIAPDEITYSY 242
>LEU2_BUCAI (P56934) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 471 Score = 114 bits (286), Expect = 2e-25 Identities = 64/162 (39%), Positives = 93/162 (57%) Frame = +3 Query: 123 CQEQKIKYFYDIKDLSDFRANPDYKGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQF 302 C E I YDIK NP+ +G+ H+ ++G PG ++ DSHT GAFG Sbjct: 90 CSEFNIS-LYDIK-------NPN-QGIVHVISPEKGMTLPGMTIVCGDSHTSTHGAFGAL 140 Query: 303 ATGIGNTDAGFVMGTGKALLKVPPTIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRS 482 + GIG ++ V+ T + ++ + GE+ ++ AKDLIL IIG++ SG Sbjct: 141 SFGIGTSEVEHVLATQTLKQQRFKNMKIEITGEIQKFVTAKDLILFIIGKLGSSGGAGYI 200 Query: 483 MEFVGSTIESLTMEERMTLCNMVIEAGGKNGVVPADETTFKY 608 +EF G+ IE ++MEERMT+CNM IE G K+G++ DE TF Y Sbjct: 201 IEFCGNVIEKMSMEERMTICNMAIEIGAKSGLIAPDEVTFSY 242
>LEU2_PHYBL (P18250) 3-isopropylmalate dehydratase (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 744 Score = 114 bits (286), Expect = 2e-25 Identities = 61/160 (38%), Positives = 91/160 (56%) Frame = +3 Query: 129 EQKIKYFYDIKDLSDFRANPDYKGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFAT 308 E +K F +L+ F +G+ H+ ++G PG ++ DSHT GAFG A Sbjct: 81 ETNVKEF----ELTYFGMEDSRQGIVHVIGPEQGFTLPGTTVVCGDSHTSTHGAFGALAF 136 Query: 309 GIGNTDAGFVMGTGKALLKVPPTIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSME 488 GIG ++ V+ T L K +R ++GE+ P + +KD+ L +IG I +G T +E Sbjct: 137 GIGTSEVEHVLATQTLLQKKSKNMRVCVEGELTPGVTSKDVALHVIGLIGTAGGTRCVIE 196 Query: 489 FVGSTIESLTMEERMTLCNMVIEAGGKNGVVPADETTFKY 608 F GS I SL+ME RM++CNM IE G + G++ DE TF+Y Sbjct: 197 FCGSAIASLSMEARMSICNMSIEGGARAGMIAPDEITFEY 236
>LEU2_SHIDS (Q32K22) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 466 Score = 114 bits (285), Expect = 2e-25 Identities = 59/142 (41%), Positives = 81/142 (57%) Frame = +3 Query: 183 NPDYKGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFATGIGNTDAGFVMGTGKALL 362 N Y+G+ H+ ++G PG ++ DSHT GAFG A GIG ++ V+ T Sbjct: 101 NHPYQGIVHVMGPEQGVTLPGMTIVCGDSHTATHGAFGALAFGIGTSEVEHVLATQTLKQ 160 Query: 363 KVPPTIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLC 542 T++ + G+ P + AKD++L IIG+ +G T +EF G I L+ME RMTLC Sbjct: 161 GRAKTMKIEVQGKAAPGITAKDIVLAIIGKTGSAGGTGHVVEFCGEAIRDLSMEGRMTLC 220 Query: 543 NMVIEAGGKNGVVPADETTFKY 608 NM IE G K G+V DETTF Y Sbjct: 221 NMAIEMGAKAGLVAPDETTFNY 242
>LEU2_SHIBS (Q326G3) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 466 Score = 114 bits (285), Expect = 2e-25 Identities = 59/142 (41%), Positives = 81/142 (57%) Frame = +3 Query: 183 NPDYKGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFATGIGNTDAGFVMGTGKALL 362 N Y+G+ H+ ++G PG ++ DSHT GAFG A GIG ++ V+ T Sbjct: 101 NHPYQGIVHVMGPEQGVTLPGMTIVCGDSHTATHGAFGALAFGIGTSEVEHVLATQTLKQ 160 Query: 363 KVPPTIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLC 542 T++ + G+ P + AKD++L IIG+ +G T +EF G I L+ME RMTLC Sbjct: 161 GRAKTMKIEVQGKAAPGITAKDIVLAIIGKTGSAGGTGHVVEFCGEAIRDLSMEGRMTLC 220 Query: 543 NMVIEAGGKNGVVPADETTFKY 608 NM IE G K G+V DETTF Y Sbjct: 221 NMAIEMGAKAGLVAPDETTFNY 242
>LEU2_YERPS (Q66EM3) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 476 Score = 114 bits (285), Expect = 2e-25 Identities = 60/148 (40%), Positives = 87/148 (58%) Frame = +3 Query: 165 LSDFRANPDYKGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFATGIGNTDAGFVMG 344 +S + N ++G+ H+ ++G PG ++ DSHT GAFG A GIG ++ V+ Sbjct: 101 VSLYDLNHPFQGIVHVIGPEQGMTLPGMTIVCGDSHTATHGAFGSLAFGIGTSEVEHVLA 160 Query: 345 TGKALLKVPPTIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTME 524 T T+R ++G + + AKD++L IIG+ +G T +EF GS IE+L+ME Sbjct: 161 TQTLKQGRAKTMRIEVNGTVGAGITAKDIVLAIIGKTGSAGGTGHVVEFCGSAIEALSME 220 Query: 525 ERMTLCNMVIEAGGKNGVVPADETTFKY 608 RMTLCNM IE G K G+V D+TTF Y Sbjct: 221 GRMTLCNMAIEMGAKAGLVAPDDTTFAY 248
>LEU2_YERPE (Q8ZIH0) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 476 Score = 114 bits (285), Expect = 2e-25 Identities = 60/148 (40%), Positives = 87/148 (58%) Frame = +3 Query: 165 LSDFRANPDYKGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFATGIGNTDAGFVMG 344 +S + N ++G+ H+ ++G PG ++ DSHT GAFG A GIG ++ V+ Sbjct: 101 VSLYDLNHPFQGIVHVIGPEQGMTLPGMTIVCGDSHTATHGAFGSLAFGIGTSEVEHVLA 160 Query: 345 TGKALLKVPPTIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTME 524 T T+R ++G + + AKD++L IIG+ +G T +EF GS IE+L+ME Sbjct: 161 TQTLKQGRAKTMRIEVNGTVGAGITAKDIVLAIIGKTGSAGGTGHVVEFCGSAIEALSME 220 Query: 525 ERMTLCNMVIEAGGKNGVVPADETTFKY 608 RMTLCNM IE G K G+V D+TTF Y Sbjct: 221 GRMTLCNMAIEMGAKAGLVAPDDTTFAY 248
>LEU2_RHOPA (Q6ND69) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 469 Score = 114 bits (285), Expect = 2e-25 Identities = 56/138 (40%), Positives = 83/138 (60%) Frame = +3 Query: 195 KGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFATGIGNTDAGFVMGTGKALLKVPP 374 +GV H+ ++G PG ++ DSHT GAFG A GIG ++ V+ T + K Sbjct: 108 QGVVHVIGPEQGFTLPGTTIVCGDSHTSTHGAFGALAHGIGTSEVEHVLATQTLIQKKAK 167 Query: 375 TIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVI 554 +R +DG++P + AKD+IL IIGEI +G T +E+ G I SL+ME RMT+CNM I Sbjct: 168 NMRVTVDGQLPDGVTAKDVILAIIGEIGTAGGTGYVLEYAGDAIRSLSMEGRMTVCNMSI 227 Query: 555 EAGGKNGVVPADETTFKY 608 E G + G++ DE +++ Sbjct: 228 EGGARAGLIAPDERAYEF 245
>LEU2_BUCUM (Q9EVG8) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) (Fragment) Length = 444 Score = 114 bits (285), Expect = 2e-25 Identities = 61/157 (38%), Positives = 93/157 (59%), Gaps = 6/157 (3%) Frame = +3 Query: 156 IKDLSDFRA------NPDYKGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFATGIG 317 IK+ DF NP+ +G+ H+ ++G PG ++ DSHT GAFG A GIG Sbjct: 88 IKNCRDFNIPLYDINNPN-QGIVHVIAPEKGMTLPGMTIVCGDSHTSTHGAFGALAFGIG 146 Query: 318 NTDAGFVMGTGKALLKVPPTIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSMEFVG 497 ++ V+ T K ++ + G++P ++ AKD+IL IIG++ S T +EF G Sbjct: 147 TSEVEHVLATQTLKQKRFKNMKVEIIGKIPKFVTAKDIILFIIGQLGSSSGTGYVIEFCG 206 Query: 498 STIESLTMEERMTLCNMVIEAGGKNGVVPADETTFKY 608 I++++MEERMT+CNM IE G K+G++ DE T+KY Sbjct: 207 DVIKNISMEERMTICNMAIEMGAKSGLIAPDEITYKY 243
>LEU2_ECOLI (P0A6A6) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 465 Score = 114 bits (285), Expect = 2e-25 Identities = 59/142 (41%), Positives = 81/142 (57%) Frame = +3 Query: 183 NPDYKGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFATGIGNTDAGFVMGTGKALL 362 N Y+G+ H+ ++G PG ++ DSHT GAFG A GIG ++ V+ T Sbjct: 100 NHPYQGIVHVMGPEQGVTLPGMTIVCGDSHTATHGAFGALAFGIGTSEVEHVLATQTLKQ 159 Query: 363 KVPPTIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLC 542 T++ + G+ P + AKD++L IIG+ +G T +EF G I L+ME RMTLC Sbjct: 160 GRAKTMKIEVQGKAAPGITAKDIVLAIIGKTGSAGGTGHVVEFCGEAIRDLSMEGRMTLC 219 Query: 543 NMVIEAGGKNGVVPADETTFKY 608 NM IE G K G+V DETTF Y Sbjct: 220 NMAIEMGAKAGLVAPDETTFNY 241
>LEU2_ECOL6 (P0A6A7) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 465 Score = 114 bits (285), Expect = 2e-25 Identities = 59/142 (41%), Positives = 81/142 (57%) Frame = +3 Query: 183 NPDYKGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFATGIGNTDAGFVMGTGKALL 362 N Y+G+ H+ ++G PG ++ DSHT GAFG A GIG ++ V+ T Sbjct: 100 NHPYQGIVHVMGPEQGVTLPGMTIVCGDSHTATHGAFGALAFGIGTSEVEHVLATQTLKQ 159 Query: 363 KVPPTIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLC 542 T++ + G+ P + AKD++L IIG+ +G T +EF G I L+ME RMTLC Sbjct: 160 GRAKTMKIEVQGKAAPGITAKDIVLAIIGKTGSAGGTGHVVEFCGEAIRDLSMEGRMTLC 219 Query: 543 NMVIEAGGKNGVVPADETTFKY 608 NM IE G K G+V DETTF Y Sbjct: 220 NMAIEMGAKAGLVAPDETTFNY 241
>LEU2_ECO57 (Q8XA00) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 465 Score = 114 bits (285), Expect = 2e-25 Identities = 59/142 (41%), Positives = 81/142 (57%) Frame = +3 Query: 183 NPDYKGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFATGIGNTDAGFVMGTGKALL 362 N Y+G+ H+ ++G PG ++ DSHT GAFG A GIG ++ V+ T Sbjct: 100 NHPYQGIVHVMGPEQGVTLPGMTIVCGDSHTATHGAFGALAFGIGTSEVEHVLATQTLKQ 159 Query: 363 KVPPTIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLC 542 T++ + G+ P + AKD++L IIG+ +G T +EF G I L+ME RMTLC Sbjct: 160 GRAKTMKIEVQGKAAPGITAKDIVLAIIGKTGSAGGTGHVVEFCGEAIRDLSMEGRMTLC 219 Query: 543 NMVIEAGGKNGVVPADETTFKY 608 NM IE G K G+V DETTF Y Sbjct: 220 NMAIEMGAKAGLVAPDETTFNY 241
>LEU2_BUCUO (Q9EVI0) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) (Fragment) Length = 443 Score = 114 bits (285), Expect = 2e-25 Identities = 62/162 (38%), Positives = 95/162 (58%) Frame = +3 Query: 123 CQEQKIKYFYDIKDLSDFRANPDYKGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQF 302 CQE I YDI NP+ +G+ H+ ++G PG ++ DSHT GAFG Sbjct: 90 CQEFNIS-LYDIN-------NPN-QGIVHVIAPEKGMTLPGMTIVCGDSHTSTHGAFGAL 140 Query: 303 ATGIGNTDAGFVMGTGKALLKVPPTIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRS 482 + GIG ++ V+ T K ++ + GE+P ++ AKD+IL IIG++ S T Sbjct: 141 SFGIGTSEVEHVLATQTLKQKRFKNMKIEIVGEIPKFVTAKDIILFIIGKLGSSSGTGYV 200 Query: 483 MEFVGSTIESLTMEERMTLCNMVIEAGGKNGVVPADETTFKY 608 +EF G+ ++ ++MEERMT+CNM IE G K+G++ DE T++Y Sbjct: 201 IEFCGNVVKKMSMEERMTVCNMAIEMGAKSGLIAPDEITYEY 242
>LEU2_GLUOX (Q5FUG3) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 475 Score = 114 bits (284), Expect = 3e-25 Identities = 59/138 (42%), Positives = 81/138 (58%) Frame = +3 Query: 195 KGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFATGIGNTDAGFVMGTGKALLKVPP 374 +G+ H+ ++G PG ++ DSHT GA G A GIG ++ V+ T L K Sbjct: 110 QGIVHVVGPEQGISLPGMTIVCGDSHTSTHGALGSLAFGIGTSEVEHVLATQTILQKPAK 169 Query: 375 TIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVI 554 +R ++G++ P + AKD++L IIG I +G T +EF GS I L M RMTLCNM I Sbjct: 170 NMRVSVEGKVGPGVTAKDILLAIIGRIGTAGGTGHVIEFAGSAIRDLDMAGRMTLCNMSI 229 Query: 555 EAGGKNGVVPADETTFKY 608 EAG + G+V DETTF Y Sbjct: 230 EAGARAGLVAPDETTFAY 247
>LEU2_SALPA (Q5PDG3) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 466 Score = 114 bits (284), Expect = 3e-25 Identities = 59/142 (41%), Positives = 81/142 (57%) Frame = +3 Query: 183 NPDYKGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFATGIGNTDAGFVMGTGKALL 362 N Y+G+ H+ ++G PG ++ DSHT GAFG A GIG ++ V+ T Sbjct: 101 NHPYQGIVHVMGPEQGVTLPGMTIVCGDSHTATHGAFGALAFGIGTSEVEHVLATQTLKQ 160 Query: 363 KVPPTIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLC 542 T++ + G P + AKD++L IIG+ +G T +EF G I +L+ME RMTLC Sbjct: 161 GRAKTMKIEVTGSAAPGITAKDIVLAIIGKTGSAGGTGHVVEFCGDAIRALSMEGRMTLC 220 Query: 543 NMVIEAGGKNGVVPADETTFKY 608 NM IE G K G+V DETTF Y Sbjct: 221 NMAIEMGAKAGLVAPDETTFNY 242
>LEU21_SALCH (Q57TE8) 3-isopropylmalate dehydratase large subunit 1 (EC| 4.2.1.33) (Isopropylmalate isomerase 1) (Alpha-IPM isomerase 1) (IPMI 1) Length = 466 Score = 114 bits (284), Expect = 3e-25 Identities = 59/142 (41%), Positives = 81/142 (57%) Frame = +3 Query: 183 NPDYKGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFATGIGNTDAGFVMGTGKALL 362 N Y+G+ H+ ++G PG ++ DSHT GAFG A GIG ++ V+ T Sbjct: 101 NHPYQGIVHVMGPEQGVTLPGMTIVCGDSHTATHGAFGALAFGIGTSEVEHVLATQTLKQ 160 Query: 363 KVPPTIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLC 542 T++ + G P + AKD++L IIG+ +G T +EF G I +L+ME RMTLC Sbjct: 161 GRAKTMKIEVTGNAAPGITAKDIVLAIIGKTGSAGGTGHVVEFCGDAIRALSMEGRMTLC 220 Query: 543 NMVIEAGGKNGVVPADETTFKY 608 NM IE G K G+V DETTF Y Sbjct: 221 NMAIEMGAKAGLVAPDETTFNY 242
>LEU2_XANCP (P58949) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 479 Score = 114 bits (284), Expect = 3e-25 Identities = 56/146 (38%), Positives = 87/146 (59%) Frame = +3 Query: 171 DFRANPDYKGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFATGIGNTDAGFVMGTG 350 +F+ N +G+ H+ ++G PG ++ DSHT GAFG A GIG ++ V+ T Sbjct: 103 EFKMNDTRQGIVHVVGPEQGATLPGMTVVCGDSHTSTHGAFGALAHGIGTSEVEHVLATQ 162 Query: 351 KALLKVPPTIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEER 530 + K ++ ++G +P + AKD++L +IG+I +G ++EF GS I +L+ME R Sbjct: 163 CLIAKKMKNLQVRVEGTLPFGVTAKDIVLAVIGKIGTAGGNGHALEFAGSAIRALSMEGR 222 Query: 531 MTLCNMVIEAGGKNGVVPADETTFKY 608 MT+CNM IEAG + G+V DE T Y Sbjct: 223 MTICNMSIEAGARVGMVAVDEKTIAY 248
>LEU2_XANC8 (Q4UYG5) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 479 Score = 114 bits (284), Expect = 3e-25 Identities = 56/146 (38%), Positives = 87/146 (59%) Frame = +3 Query: 171 DFRANPDYKGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFATGIGNTDAGFVMGTG 350 +F+ N +G+ H+ ++G PG ++ DSHT GAFG A GIG ++ V+ T Sbjct: 103 EFKMNDTRQGIVHVVGPEQGATLPGMTVVCGDSHTSTHGAFGALAHGIGTSEVEHVLATQ 162 Query: 351 KALLKVPPTIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEER 530 + K ++ ++G +P + AKD++L +IG+I +G ++EF GS I +L+ME R Sbjct: 163 CLIAKKMKNLQVRVEGTLPFGVTAKDIVLAVIGKIGTAGGNGHALEFAGSAIRALSMEGR 222 Query: 531 MTLCNMVIEAGGKNGVVPADETTFKY 608 MT+CNM IEAG + G+V DE T Y Sbjct: 223 MTICNMSIEAGARVGMVAVDEKTIAY 248
>LEU2_XANAC (P58948) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 479 Score = 114 bits (284), Expect = 3e-25 Identities = 56/146 (38%), Positives = 87/146 (59%) Frame = +3 Query: 171 DFRANPDYKGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFATGIGNTDAGFVMGTG 350 +F+ N +G+ H+ ++G PG ++ DSHT GAFG A GIG ++ V+ T Sbjct: 103 EFKMNDARQGIVHVVGPEQGATLPGMTVVCGDSHTSTHGAFGALAHGIGTSEVEHVLATQ 162 Query: 351 KALLKVPPTIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEER 530 + K ++ ++G +P + AKD++L +IG+I +G ++EF GS I +L+ME R Sbjct: 163 CLIAKKMKNMQVRVEGTLPFGVTAKDIVLAVIGKIGTAGGNGHALEFAGSAIRTLSMEGR 222 Query: 531 MTLCNMVIEAGGKNGVVPADETTFKY 608 MT+CNM IEAG + G+V DE T Y Sbjct: 223 MTICNMAIEAGARVGMVAVDEKTIAY 248
>LEU2_RALSO (Q8XXX3) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 469 Score = 114 bits (284), Expect = 3e-25 Identities = 58/148 (39%), Positives = 87/148 (58%) Frame = +3 Query: 165 LSDFRANPDYKGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFATGIGNTDAGFVMG 344 ++ F+ +G+ H+ ++G PG ++ DSHT GAFG A GIG ++ V+ Sbjct: 95 ITQFKMTDKRQGIVHVIGPEQGATLPGMTVVCGDSHTSTHGAFGALAHGIGTSEVEHVLA 154 Query: 345 TGKALLKVPPTIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTME 524 T L K + ++G +P AKD++L IIG+I +G T +MEF GS I +L+ME Sbjct: 155 TQTLLAKKSKNMLVKVEGTLPRGCTAKDIVLAIIGKIGTAGGTGYAMEFGGSAIRALSME 214 Query: 525 ERMTLCNMVIEAGGKNGVVPADETTFKY 608 RMT+CNM IEAG + G+V D+ T +Y Sbjct: 215 GRMTVCNMAIEAGARAGMVGVDDITLEY 242
>LEU2_SALTI (Q8Z9I2) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 465 Score = 114 bits (284), Expect = 3e-25 Identities = 59/142 (41%), Positives = 81/142 (57%) Frame = +3 Query: 183 NPDYKGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFATGIGNTDAGFVMGTGKALL 362 N Y+G+ H+ ++G PG ++ DSHT GAFG A GIG ++ V+ T Sbjct: 100 NHPYQGIVHVMGPEQGVTLPGMTIVCGDSHTATHGAFGALAFGIGTSEVEHVLATQTLKQ 159 Query: 363 KVPPTIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLC 542 T++ + G P + AKD++L IIG+ +G T +EF G I +L+ME RMTLC Sbjct: 160 GRAKTMKIEVTGNAAPGITAKDIVLAIIGKTGSAGGTGHVVEFCGDAIRALSMEGRMTLC 219 Query: 543 NMVIEAGGKNGVVPADETTFKY 608 NM IE G K G+V DETTF Y Sbjct: 220 NMAIEMGAKAGLVAPDETTFNY 241
>LEU21_SALTY (P15717) 3-isopropylmalate dehydratase large subunit 1 (EC| 4.2.1.33) (Isopropylmalate isomerase 1) (Alpha-IPM isomerase 1) (IPMI 1) Length = 465 Score = 114 bits (284), Expect = 3e-25 Identities = 59/142 (41%), Positives = 81/142 (57%) Frame = +3 Query: 183 NPDYKGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFATGIGNTDAGFVMGTGKALL 362 N Y+G+ H+ ++G PG ++ DSHT GAFG A GIG ++ V+ T Sbjct: 100 NHPYQGIVHVMGPEQGVTLPGMTIVCGDSHTATHGAFGALAFGIGTSEVEHVLATQTLKQ 159 Query: 363 KVPPTIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLC 542 T++ + G P + AKD++L IIG+ +G T +EF G I +L+ME RMTLC Sbjct: 160 GRAKTMKIEVTGNAAPGITAKDIVLAIIGKTGSAGGTGHVVEFCGDAIRALSMEGRMTLC 219 Query: 543 NMVIEAGGKNGVVPADETTFKY 608 NM IE G K G+V DETTF Y Sbjct: 220 NMAIEMGAKAGLVAPDETTFNY 241
>LEU2_BUCUL (Q9AQC6) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) (Fragment) Length = 369 Score = 113 bits (283), Expect = 4e-25 Identities = 59/160 (36%), Positives = 95/160 (59%) Frame = +3 Query: 129 EQKIKYFYDIKDLSDFRANPDYKGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFAT 308 EQ IK D ++S + N +G+ H+ ++G PG +++ DSHT GAFG + Sbjct: 11 EQLIKNC-DEFNISLYDINNPNQGIVHVIAPEKGMTLPGMIIVCGDSHTSTHGAFGALSF 69 Query: 309 GIGNTDAGFVMGTGKALLKVPPTIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSME 488 GIG ++ V+ T + ++ + G++P ++ AKD+IL +IG + SG T +E Sbjct: 70 GIGTSEVEHVLATQTLKQQRFKNMKIEIIGDVPQFVTAKDIILFVIGRLGSSGGTGYVIE 129 Query: 489 FVGSTIESLTMEERMTLCNMVIEAGGKNGVVPADETTFKY 608 F G+ I+ ++MEERMT+CNM IE G K+G++ DE T+ Y Sbjct: 130 FCGNVIKKMSMEERMTVCNMAIEMGAKSGIIAPDEITYSY 169
>LEU2_XANOR (Q5H4D1) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 482 Score = 113 bits (283), Expect = 4e-25 Identities = 56/146 (38%), Positives = 87/146 (59%) Frame = +3 Query: 171 DFRANPDYKGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFATGIGNTDAGFVMGTG 350 +F+ N +G+ H+ ++G PG ++ DSHT GAFG A GIG ++ V+ T Sbjct: 103 EFKMNDARQGIVHVVGPEQGATLPGMTVVCGDSHTSTHGAFGALAHGIGTSEVEHVLATQ 162 Query: 351 KALLKVPPTIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEER 530 + K ++ ++G +P + AKD++L +IG+I +G ++EF GS I +L+ME R Sbjct: 163 CLITKKMKNLQVRVEGTLPFGVTAKDIVLAVIGKIGTAGGNGHALEFAGSAIRALSMEGR 222 Query: 531 MTLCNMVIEAGGKNGVVPADETTFKY 608 MT+CNM IEAG + G+V DE T Y Sbjct: 223 MTICNMSIEAGARVGMVAVDEKTIAY 248
>LEU2_LISMO (Q8Y5R7) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 462 Score = 113 bits (283), Expect = 4e-25 Identities = 55/140 (39%), Positives = 87/140 (62%) Frame = +3 Query: 189 DYKGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFATGIGNTDAGFVMGTGKALLKV 368 D +G+ H+ + G +PG+V++ DSHT GAFG GIG+++ V T + Sbjct: 102 DRQGIVHMVGPETGLTQPGKVIVCGDSHTATHGAFGAIGFGIGSSEVEHVFATQTIWQQK 161 Query: 369 PPTIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNM 548 P ++ ++G++P + AKD+IL +I V+ T ++E+ G TI +++MEERMT+CNM Sbjct: 162 PKSMGIEINGKLPKGVYAKDIILHLIATYGVAFGTGYAVEYYGETIRNMSMEERMTICNM 221 Query: 549 VIEAGGKNGVVPADETTFKY 608 IE G K G++ DETTF+Y Sbjct: 222 AIEGGAKMGMMAPDETTFEY 241
>LEU2_BUCUH (Q9EVH7) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) (Fragment) Length = 442 Score = 113 bits (282), Expect = 5e-25 Identities = 58/161 (36%), Positives = 95/161 (59%) Frame = +3 Query: 126 QEQKIKYFYDIKDLSDFRANPDYKGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFA 305 Q Q++ D ++S + N +G+ H+ ++G PG +++ DSHT GAFG + Sbjct: 82 QMQQLIRNCDEFNISLYDINNPNQGIVHVIAPEKGMTLPGMIIVCGDSHTSTHGAFGALS 141 Query: 306 TGIGNTDAGFVMGTGKALLKVPPTIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSM 485 GIG ++ V+ T + ++ + G++P ++ AKD+IL II + SG + + Sbjct: 142 FGIGTSEVEHVLATQTLKQQCFKNMKVEIVGDIPKFVTAKDIILFIIRRLGSSGGSGYVI 201 Query: 486 EFVGSTIESLTMEERMTLCNMVIEAGGKNGVVPADETTFKY 608 EF G+ IE ++MEERMT+CNM IE G K+G++ DETT+ Y Sbjct: 202 EFCGNVIEKMSMEERMTVCNMAIEMGAKSGIIAPDETTYAY 242
>LEU2_LISMF (Q71Y33) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 462 Score = 113 bits (282), Expect = 5e-25 Identities = 55/140 (39%), Positives = 86/140 (61%) Frame = +3 Query: 189 DYKGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFATGIGNTDAGFVMGTGKALLKV 368 D +G+ H+ + G +PG+V++ DSHT GAFG GIG+++ V T + Sbjct: 102 DRQGIVHMVGPETGLTQPGKVIVCGDSHTATHGAFGAIGFGIGSSEVEHVFATQTIWQQK 161 Query: 369 PPTIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNM 548 P ++ ++G +P + AKD+IL +I V+ T ++E+ G TI +++MEERMT+CNM Sbjct: 162 PKSMGIEINGNLPKGVYAKDIILHLIATYGVAFGTGYAVEYYGETIRNMSMEERMTICNM 221 Query: 549 VIEAGGKNGVVPADETTFKY 608 IE G K G++ DETTF+Y Sbjct: 222 AIEGGAKMGMMAPDETTFEY 241
>LEU2_BUCUE (Q9EVH4) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) (Fragment) Length = 443 Score = 113 bits (282), Expect = 5e-25 Identities = 60/160 (37%), Positives = 93/160 (58%) Frame = +3 Query: 129 EQKIKYFYDIKDLSDFRANPDYKGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFAT 308 EQ IK + ++S + N +G+ H+ ++G PG ++ DSHT GAFG + Sbjct: 84 EQLIKNCNEF-NISLYDVNNPNQGIVHVIAPEKGMTLPGMTIVCGDSHTSTHGAFGALSF 142 Query: 309 GIGNTDAGFVMGTGKALLKVPPTIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSME 488 GIG ++ V+ T K ++ + G++P ++ AKD+IL IIG++ S T +E Sbjct: 143 GIGTSEVEHVLATQTLKQKRFKNMKITIIGKVPEFITAKDIILFIIGQLGSSRGTGYVIE 202 Query: 489 FVGSTIESLTMEERMTLCNMVIEAGGKNGVVPADETTFKY 608 F G I +++MEERMTLCNM IE G K+G++ DE T+ Y Sbjct: 203 FFGDVINNMSMEERMTLCNMAIEMGAKSGLIAPDEITYSY 242
>LEU2_THIDA (Q3SHL1) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 467 Score = 112 bits (281), Expect = 6e-25 Identities = 59/148 (39%), Positives = 88/148 (59%) Frame = +3 Query: 165 LSDFRANPDYKGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFATGIGNTDAGFVMG 344 +++FR + +G+ H+ +EG PG ++ DSHT GAFG A GIG ++ V+ Sbjct: 96 ITEFRMDDVRQGIVHVIGPEEGLTLPGMTVVCGDSHTSTHGAFGALAFGIGTSEVEHVLA 155 Query: 345 TGKALLKVPPTIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTME 524 T K T+ ++GE+ + AKD+ L +IG I +G T ++EF G+ I +L+ME Sbjct: 156 TQCLWQKPSKTMLVKVEGELGKGVTAKDIALAVIGRIGTAGGTGYAIEFGGAAIRALSME 215 Query: 525 ERMTLCNMVIEAGGKNGVVPADETTFKY 608 RMTLCNM IEAG + G+V D+TT Y Sbjct: 216 GRMTLCNMAIEAGARAGMVAVDQTTIDY 243
>LEU2_CAUCR (Q9ABN0) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 479 Score = 112 bits (281), Expect = 6e-25 Identities = 56/137 (40%), Positives = 79/137 (57%) Frame = +3 Query: 198 GVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFATGIGNTDAGFVMGTGKALLKVPPT 377 G+ H+ ++G +PG ++ DSHT GAFG A GIG ++ V+ T K Sbjct: 109 GIVHVVGPEQGRTQPGMTIVCGDSHTSTHGAFGALAHGIGTSEVEHVLATQTLRQKKAKN 168 Query: 378 IRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIE 557 + +DG++PP + KD+ L +IGEI +G T +EF G I L+ME RMTLCN+ IE Sbjct: 169 MLVRVDGQLPPGVTGKDVALAVIGEIGTAGGTGYVIEFAGEAIAGLSMEGRMTLCNLTIE 228 Query: 558 AGGKNGVVPADETTFKY 608 G K G+V D+ TF Y Sbjct: 229 GGAKAGLVAPDDKTFAY 245
>LEU2_VIBPA (Q87SS9) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 471 Score = 112 bits (280), Expect = 8e-25 Identities = 57/142 (40%), Positives = 83/142 (58%) Frame = +3 Query: 183 NPDYKGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFATGIGNTDAGFVMGTGKALL 362 N Y+G+ H+ + G PG ++ DSHT GAFG A GIG ++ V+ T Sbjct: 101 NHKYQGIVHVMGPELGITLPGMTIVCGDSHTATHGAFGSLAFGIGTSEVEHVLATQTLKQ 160 Query: 363 KVPPTIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLC 542 T++ + G++ P + AKD++L IIG+ + +G T +EF G I L+ME RMT+C Sbjct: 161 ARAKTMKIEVKGKVAPGITAKDIVLAIIGKTTAAGGTGYVVEFCGEAITDLSMEGRMTVC 220 Query: 543 NMVIEAGGKNGVVPADETTFKY 608 NM IE G K G++ DETTF+Y Sbjct: 221 NMAIELGAKAGLIAPDETTFEY 242
>LEU2_XANC5 (Q3BPJ6) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 482 Score = 112 bits (280), Expect = 8e-25 Identities = 55/146 (37%), Positives = 86/146 (58%) Frame = +3 Query: 171 DFRANPDYKGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFATGIGNTDAGFVMGTG 350 +F+ N +G+ H+ ++G PG ++ DSHT GAFG A GIG ++ V+ T Sbjct: 103 EFKMNDTRQGIVHVVGPEQGATLPGMTVVCGDSHTSTHGAFGALAHGIGTSEVEHVLATQ 162 Query: 351 KALLKVPPTIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEER 530 + K ++ ++G +P + AKD++L +IG+I +G ++EF GS I + +ME R Sbjct: 163 CLIAKKMKNMQVRVEGTLPFGVTAKDIVLAVIGKIGTAGGNGHALEFAGSAIRAASMEGR 222 Query: 531 MTLCNMVIEAGGKNGVVPADETTFKY 608 MT+CNM IEAG + G+V DE T Y Sbjct: 223 MTICNMAIEAGARVGMVAVDEKTIAY 248
>LEU2_LISIN (Q92A26) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 462 Score = 112 bits (280), Expect = 8e-25 Identities = 54/140 (38%), Positives = 87/140 (62%) Frame = +3 Query: 189 DYKGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFATGIGNTDAGFVMGTGKALLKV 368 D +G+ H+ + G +PG+V++ DSHT GAFG GIG+++ V T + Sbjct: 102 DRQGIVHMVGPETGLTQPGKVIVCGDSHTATHGAFGAIGFGIGSSEVEHVFATQTIWQQK 161 Query: 369 PPTIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNM 548 P ++ ++G++P + AKD+IL +I V+ T ++E+ G TI +++MEERMT+CNM Sbjct: 162 PKSMGIEINGKLPKGVYAKDIILHLIATYGVAFGTGYAVEYYGETIRNMSMEERMTICNM 221 Query: 549 VIEAGGKNGVVPADETTFKY 608 IE G K G++ D+TTF+Y Sbjct: 222 AIEGGAKMGMMAPDQTTFEY 241
>LEU2_SHIFL (Q821C2) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 466 Score = 112 bits (279), Expect = 1e-24 Identities = 58/142 (40%), Positives = 80/142 (56%) Frame = +3 Query: 183 NPDYKGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFATGIGNTDAGFVMGTGKALL 362 N Y+G+ H+ ++G PG ++ DSHT GAFG A GIG ++ V+ T Sbjct: 101 NHPYQGIVHVMGPEQGVTLPGMTIVCGDSHTATHGAFGALAFGIGTSEVEHVLATQTLKQ 160 Query: 363 KVPPTIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLC 542 T++ + G+ P + AKD++L IIG+ +G T +EF G I L+ME RMTLC Sbjct: 161 GRAKTMKIEVQGKAAPGITAKDIVLAIIGKTGSAGGTGHVVEFCGEAIRDLSMEGRMTLC 220 Query: 543 NMVIEAGGKNGVVPADETTFKY 608 NM IE G K +V DETTF Y Sbjct: 221 NMAIEMGAKAALVAPDETTFNY 242
>LEU2_ERWCT (Q6D0G6) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 466 Score = 112 bits (279), Expect = 1e-24 Identities = 58/142 (40%), Positives = 81/142 (57%) Frame = +3 Query: 183 NPDYKGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFATGIGNTDAGFVMGTGKALL 362 N Y+G+ H+ ++G PG ++ DSHT GAFG A GIG ++ V+ T Sbjct: 101 NHPYQGIVHVIGPEQGMTLPGMTIVCGDSHTATHGAFGSLAFGIGTSEVEHVLATQTLKQ 160 Query: 363 KVPPTIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLC 542 T++ + G+ + AKD++L IIG+ +G T +EF G I +L+ME RMTLC Sbjct: 161 GRAKTMKIEVTGDAAHGITAKDIVLAIIGKTGSAGGTGHVVEFCGKAIRALSMEGRMTLC 220 Query: 543 NMVIEAGGKNGVVPADETTFKY 608 NM IE G K G+V DETTF Y Sbjct: 221 NMAIEMGAKAGLVAPDETTFNY 242
>LEU2_RHIRA (P17279) 3-isopropylmalate dehydratase (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 644 Score = 112 bits (279), Expect = 1e-24 Identities = 62/160 (38%), Positives = 90/160 (56%) Frame = +3 Query: 129 EQKIKYFYDIKDLSDFRANPDYKGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFAT 308 EQ I+ F L+ F +G+ H+ ++G P ++ DSHT GAFG A Sbjct: 140 EQNIEAF----GLTYFGMEDSRQGIVHVIGPEQGFTLPATTVVCGDSHTSTHGAFGALAF 195 Query: 309 GIGNTDAGFVMGTGKALLKVPPTIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSME 488 GIG ++ V+ T L K +R + G+ P + +KD++L IIG I +G T +E Sbjct: 196 GIGTSEVEHVLATQTLLQKKSKNMRIRVQGKALPGVTSKDIVLHIIGVIGTAGGTGCVIE 255 Query: 489 FVGSTIESLTMEERMTLCNMVIEAGGKNGVVPADETTFKY 608 F G TI +L+ME RM++CNM IEAG + G+V DE TF+Y Sbjct: 256 FCGDTIAALSMESRMSICNMSIEAGARAGMVAPDEVTFEY 295
>LEU21_BRAJA (Q89X98) 3-isopropylmalate dehydratase large subunit 1 (EC| 4.2.1.33) (Isopropylmalate isomerase 1) (Alpha-IPM isomerase 1) (IPMI 1) Length = 477 Score = 112 bits (279), Expect = 1e-24 Identities = 53/138 (38%), Positives = 83/138 (60%) Frame = +3 Query: 195 KGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFATGIGNTDAGFVMGTGKALLKVPP 374 +G+ H+ + G PG +++ DSHTC G G A GIG+++ V+ T + + P Sbjct: 115 QGIVHVIGPELGLSLPGCLIVCGDSHTCTHGGLGALAFGIGSSELTHVLATQTIIQRRPK 174 Query: 375 TIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVI 554 T+R DG MP + AKDLIL +IG + +G T ++E+ GS I + +E R+T+CN+ + Sbjct: 175 TMRVTFDGRMPFGVTAKDLILALIGHVGAAGGTGYAVEYAGSAIRGMPIEGRLTICNLSV 234 Query: 555 EAGGKNGVVPADETTFKY 608 E G K G++ D+TTF Y Sbjct: 235 ELGAKMGLIAPDQTTFDY 252
>LEU2_BACHD (Q9K8F0) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 472 Score = 112 bits (279), Expect = 1e-24 Identities = 57/137 (41%), Positives = 80/137 (58%) Frame = +3 Query: 198 GVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFATGIGNTDAGFVMGTGKALLKVPPT 377 G+ H+ + G +PG+ ++ DSHT GAFG A GIG ++ V+ T P T Sbjct: 106 GIVHVIGPELGLTQPGKTIVCGDSHTSTHGAFGALAFGIGTSEVEHVLATQTLWQSKPKT 165 Query: 378 IRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIE 557 + + GE+ P + AKD+IL +I + V T +EF G I SL+MEERMT+CNM IE Sbjct: 166 MEVRVTGELAPSVSAKDIILAVIAKYGVDFGTGHVIEFTGEAIRSLSMEERMTICNMSIE 225 Query: 558 AGGKNGVVPADETTFKY 608 AG K G++ D TF+Y Sbjct: 226 AGAKAGLISPDSVTFEY 242
>LEU2_MYCPA (Q73VI7) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 476 Score = 111 bits (278), Expect = 1e-24 Identities = 57/138 (41%), Positives = 85/138 (61%) Frame = +3 Query: 195 KGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFATGIGNTDAGFVMGTGKALLKVPP 374 +G+ H+ Q G +PG ++ DSHT GAFG A GIG ++ V+ T L+ Sbjct: 115 QGIVHVVGPQLGLTQPGMTVVCGDSHTSTHGAFGALAMGIGTSEVEHVLATQTLPLRPFK 174 Query: 375 TIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVI 554 T+ +DGE+P + AKD+IL +I +I G +E+ GS IESL+ME RMT+CNM I Sbjct: 175 TMAVNVDGELPAGVTAKDIILALIAKIGTGGGQGHVIEYRGSAIESLSMEGRMTVCNMSI 234 Query: 555 EAGGKNGVVPADETTFKY 608 EAG + G++ D+TT+++ Sbjct: 235 EAGARAGMIAPDDTTYEF 252
>LEU2_MYCLE (O33123) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 476 Score = 111 bits (278), Expect = 1e-24 Identities = 57/138 (41%), Positives = 84/138 (60%) Frame = +3 Query: 195 KGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFATGIGNTDAGFVMGTGKALLKVPP 374 +G+ H+ Q G +PG ++ DSHT GAFG A GIG ++ V+ T L+ Sbjct: 115 QGIVHVVGPQLGLTQPGMTIVCGDSHTSTHGAFGAIAMGIGTSEIEHVLATQTLPLRPFK 174 Query: 375 TIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVI 554 T+ +DG +P + AKD+IL +I +I G +E+ GS IES++ME RMT+CNM I Sbjct: 175 TMAVTVDGRLPAGVTAKDIILALIAKIGTGGGQGYVLEYRGSVIESMSMEGRMTICNMSI 234 Query: 555 EAGGKNGVVPADETTFKY 608 EAG + G+V DETT+++ Sbjct: 235 EAGARAGMVAPDETTYEF 252
>LEU2_PHOLL (Q7N127) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 469 Score = 111 bits (278), Expect = 1e-24 Identities = 58/142 (40%), Positives = 83/142 (58%) Frame = +3 Query: 183 NPDYKGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFATGIGNTDAGFVMGTGKALL 362 N Y+G+ H+ ++G PG ++ DSHT GAFG A GIG ++ V+ + Sbjct: 101 NHPYQGIVHVIGPEQGITLPGMTIVCGDSHTATHGAFGSLAFGIGTSEVEHVLASQTLKQ 160 Query: 363 KVPPTIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLC 542 T++ + G++ + AKD++L IIG+ +G T +EF G IE+L+ME RMTLC Sbjct: 161 ARAKTMKIEVMGDVGDAITAKDIVLAIIGKTGSAGGTGYVVEFCGKAIEALSMEGRMTLC 220 Query: 543 NMVIEAGGKNGVVPADETTFKY 608 NM IE G K G+V DETTF Y Sbjct: 221 NMAIEMGAKAGLVAPDETTFTY 242
>LEU22_MANSM (Q65V07) 3-isopropylmalate dehydratase large subunit 2 (EC| 4.2.1.33) (Isopropylmalate isomerase 2) (Alpha-IPM isomerase 2) (IPMI 2) Length = 469 Score = 111 bits (278), Expect = 1e-24 Identities = 58/148 (39%), Positives = 87/148 (58%) Frame = +3 Query: 165 LSDFRANPDYKGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFATGIGNTDAGFVMG 344 +S F N +G+ H+ ++G PG ++ DSHT GAFG A GIG ++ V+ Sbjct: 95 ISLFDMNTKEQGIVHVMGPEQGLTLPGMTIVCGDSHTATHGAFGALAFGIGTSEVEHVLA 154 Query: 345 TGKALLKVPPTIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTME 524 T +++ + G++ P + AKD++L IIG+ +++G T +EF G I L+ME Sbjct: 155 TQTLKQARAKSMKVEVRGKVNPGITAKDIVLAIIGKTTMAGGTGHVVEFCGEAIRDLSME 214 Query: 525 ERMTLCNMVIEAGGKNGVVPADETTFKY 608 RMT+CNM IE G K G+V DETTF+Y Sbjct: 215 GRMTVCNMAIEFGAKAGLVAPDETTFEY 242
>LEU2_XYLFT (Q87BP9) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 474 Score = 111 bits (278), Expect = 1e-24 Identities = 56/146 (38%), Positives = 89/146 (60%) Frame = +3 Query: 171 DFRANPDYKGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFATGIGNTDAGFVMGTG 350 +F+ N +G+ H+ ++G PG ++ DSHT GAFG A GIG ++ V+ T Sbjct: 103 EFKMNDVRQGIVHVIGPEQGATLPGMTVVCGDSHTSTHGAFGALAHGIGTSEVEHVLATQ 162 Query: 351 KALLKVPPTIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEER 530 + + ++ ++G +P + AKD++L +IG+I +G ++EF GSTI +L+ME R Sbjct: 163 CLVTQKMKNMQVRVEGTLPWGVTAKDIVLALIGKIGTAGGNGYAVEFSGSTIRALSMEGR 222 Query: 531 MTLCNMVIEAGGKNGVVPADETTFKY 608 MT+CNM IEAG + G+V DE T +Y Sbjct: 223 MTICNMAIEAGARVGMVAVDEKTIQY 248
>LEU2_XYLFA (Q9PAX0) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 474 Score = 111 bits (278), Expect = 1e-24 Identities = 56/146 (38%), Positives = 89/146 (60%) Frame = +3 Query: 171 DFRANPDYKGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFATGIGNTDAGFVMGTG 350 +F+ N +G+ H+ ++G PG ++ DSHT GAFG A GIG ++ V+ T Sbjct: 103 EFKMNDVRQGIVHVIGPEQGATLPGMTVVCGDSHTSTHGAFGALAHGIGTSEVEHVLATQ 162 Query: 351 KALLKVPPTIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEER 530 + + ++ ++G +P + AKD++L +IG+I +G ++EF GSTI +L+ME R Sbjct: 163 CLVTQKMKNMQVRVEGTLPWGVTAKDIVLALIGKIGTAGGNGYAVEFSGSTIRALSMEGR 222 Query: 531 MTLCNMVIEAGGKNGVVPADETTFKY 608 MT+CNM IEAG + G+V DE T +Y Sbjct: 223 MTICNMAIEAGARVGMVAVDEKTIQY 248
>LEU2_STAHJ (Q4L7U2) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 456 Score = 111 bits (277), Expect = 2e-24 Identities = 56/138 (40%), Positives = 81/138 (58%) Frame = +3 Query: 195 KGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFATGIGNTDAGFVMGTGKALLKVPP 374 +G+ H+ + G +PG+ ++ DSHT GAFG A GIG ++ V T P Sbjct: 104 QGIVHMVGPETGLTQPGKTIVCGDSHTATHGAFGAIAFGIGTSEVEHVFATQTLWQTKPK 163 Query: 375 TIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVI 554 ++ + G++P + AKD+IL +I + V T ++EF G TI SL+ME RMT+CNM I Sbjct: 164 NLKIDVTGQLPKGVYAKDIILYLISQYGVDFGTGYAIEFTGETIRSLSMEARMTICNMAI 223 Query: 555 EAGGKNGVVPADETTFKY 608 EAG K G++ DE TF Y Sbjct: 224 EAGAKYGLMQPDEMTFAY 241
>LEU2_PSESM (Q884C2) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 475 Score = 111 bits (277), Expect = 2e-24 Identities = 55/148 (37%), Positives = 89/148 (60%) Frame = +3 Query: 165 LSDFRANPDYKGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFATGIGNTDAGFVMG 344 +++F+ N +G+ H+ ++G PG ++ DSHT GAFG A GIG ++ V+ Sbjct: 100 ITEFKMNDPRQGIVHVIGPEQGATLPGMSVVCGDSHTSTHGAFGALAHGIGTSEVEHVLA 159 Query: 345 TGKALLKVPPTIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTME 524 T + K + ++G++P + AKD++L +IG+I +G ++EF GS I L++E Sbjct: 160 TQCLVAKKMKNMLVSVEGQLPFGVTAKDIVLAVIGKIGTAGGNGYAIEFAGSAIRDLSIE 219 Query: 525 ERMTLCNMVIEAGGKNGVVPADETTFKY 608 RMT+CNM IEAG + G+V DE T +Y Sbjct: 220 GRMTICNMSIEAGARVGMVATDEKTIEY 247
>LEU2_NEIMB (Q9JZI5) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 469 Score = 111 bits (277), Expect = 2e-24 Identities = 57/138 (41%), Positives = 82/138 (59%) Frame = +3 Query: 195 KGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFATGIGNTDAGFVMGTGKALLKVPP 374 +G+ H+ ++G PG ++ DSHT GAFG A GIG ++ M T K Sbjct: 107 QGIVHVMGPEQGATLPGMTVVCGDSHTSTHGAFGALAHGIGTSEVEHTMATQCITAKKSK 166 Query: 375 TIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVI 554 ++ +DG++ + AKD+ L IIG+I +G T ++EF G I SL+ME RMTLCNM I Sbjct: 167 SMLISVDGKLKAGVTAKDVALYIIGQIGTAGGTGYAIEFGGEAIRSLSMESRMTLCNMAI 226 Query: 555 EAGGKNGVVPADETTFKY 608 EAG ++G+V D+TT Y Sbjct: 227 EAGARSGMVAVDQTTIDY 244
>LEU2_NEIMA (Q9JU82) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 469 Score = 111 bits (277), Expect = 2e-24 Identities = 57/138 (41%), Positives = 82/138 (59%) Frame = +3 Query: 195 KGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFATGIGNTDAGFVMGTGKALLKVPP 374 +G+ H+ ++G PG ++ DSHT GAFG A GIG ++ M T K Sbjct: 107 QGIVHVMGPEQGATLPGMTVVCGDSHTSTHGAFGALAHGIGTSEVEHTMATQCITAKKSK 166 Query: 375 TIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVI 554 ++ +DG++ + AKD+ L IIG+I +G T ++EF G I SL+ME RMTLCNM I Sbjct: 167 SMLIAVDGKLKAGVTAKDVALYIIGQIGTAGGTGYAIEFGGEAIRSLSMEGRMTLCNMAI 226 Query: 555 EAGGKNGVVPADETTFKY 608 EAG ++G+V D+TT Y Sbjct: 227 EAGARSGMVAVDQTTIDY 244
>LEU2_MYCTU (O53237) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 473 Score = 110 bits (276), Expect = 2e-24 Identities = 58/138 (42%), Positives = 83/138 (60%) Frame = +3 Query: 195 KGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFATGIGNTDAGFVMGTGKALLKVPP 374 +G+ H+ Q G +PG ++ DSHT GAFG A GIG ++ V+ T L+ Sbjct: 112 QGIVHVVGPQLGLTQPGMTIVCGDSHTSTHGAFGALAMGIGTSEVEHVLATQTLPLRPFK 171 Query: 375 TIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVI 554 T+ +DG +P + AKD+IL +I +I G +E+ GS IESL+ME RMT+CNM I Sbjct: 172 TMAVNVDGRLPDGVSAKDIILALIAKIGTGGGQGHVIEYRGSAIESLSMEGRMTICNMSI 231 Query: 555 EAGGKNGVVPADETTFKY 608 EAG + G+V DETT+ + Sbjct: 232 EAGARAGMVAPDETTYAF 249
>LEU2_MYCBO (Q7TXH6) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 473 Score = 110 bits (276), Expect = 2e-24 Identities = 58/138 (42%), Positives = 83/138 (60%) Frame = +3 Query: 195 KGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFATGIGNTDAGFVMGTGKALLKVPP 374 +G+ H+ Q G +PG ++ DSHT GAFG A GIG ++ V+ T L+ Sbjct: 112 QGIVHVVGPQLGLTQPGMTIVCGDSHTSTHGAFGALAMGIGTSEVEHVLATQTLPLRPFK 171 Query: 375 TIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVI 554 T+ +DG +P + AKD+IL +I +I G +E+ GS IESL+ME RMT+CNM I Sbjct: 172 TMAVNVDGRLPDGVSAKDIILALIAKIGTGGGQGHVIEYRGSAIESLSMEGRMTICNMSI 231 Query: 555 EAGGKNGVVPADETTFKY 608 EAG + G+V DETT+ + Sbjct: 232 EAGARAGMVAPDETTYAF 249
>HACA_THET2 (Q9ZNE0) Probable homoaconitase large subunit (EC 4.2.1.36)| (Homoaconitate hydratase) Length = 418 Score = 110 bits (276), Expect = 2e-24 Identities = 58/140 (41%), Positives = 86/140 (61%), Gaps = 2/140 (1%) Frame = +3 Query: 195 KGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFATGIGNTDAGFVMGTGKALLKVPP 374 +GVCH L +EG +PG V++G+DSH+ GA G F TG+G TD +G+ L+VP Sbjct: 96 RGVCHQVLIEEGLAQPGWVVVGSDSHSTTYGAVGAFGTGMGATDIALAAASGRTWLRVPE 155 Query: 375 TIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSMEF-VGSTIESLTMEERMTLCNMV 551 +++ V G +P + AKD L+++ ++ GATY ++E + E+LT ERMTL N+ Sbjct: 156 SVKVVFRGRLPKGVTAKDAALEMVRLLTAEGATYMAVEIHLLDGAEALTRGERMTLANLT 215 Query: 552 IEAGGKNG-VVPADETTFKY 608 +EAG K G VVP+ E Y Sbjct: 216 VEAGAKAGLVVPSGEILEMY 235
>LEU2_CORDI (Q6NHL0) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 480 Score = 110 bits (276), Expect = 2e-24 Identities = 60/138 (43%), Positives = 79/138 (57%) Frame = +3 Query: 195 KGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFATGIGNTDAGFVMGTGKALLKVPP 374 +G+ H Q G +PG ++ DSHT GAFG A GIG ++ VM T LK Sbjct: 119 QGIVHQVGPQLGATQPGMTIVCGDSHTSTHGAFGAMAFGIGTSEVEHVMATQTLSLKPFK 178 Query: 375 TIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVI 554 T+ + GE+ P + AKDLIL +I I G +E+ G IE L+ME RMT+CNM I Sbjct: 179 TMAINVTGELQPGVTAKDLILAVIATIGTGGGQGHVIEYRGEAIEKLSMEARMTVCNMSI 238 Query: 555 EAGGKNGVVPADETTFKY 608 EAG + G++ DETTF Y Sbjct: 239 EAGARAGMIAPDETTFDY 256
>LEU2_LEIXX (Q6AFK7) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 486 Score = 110 bits (276), Expect = 2e-24 Identities = 59/138 (42%), Positives = 82/138 (59%) Frame = +3 Query: 195 KGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFATGIGNTDAGFVMGTGKALLKVPP 374 +G+ H+ Q G PG ++ DSHT GAFG A GIG ++ V+ T LK Sbjct: 111 QGIVHVVGPQLGLTMPGITVVCGDSHTSTHGAFGAMAFGIGTSEVEHVLATQTLPLKPFK 170 Query: 375 TIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVI 554 T+ ++GE+ P + AKD+IL +I +I G +E+ GS I +L+ME RMT+CNM I Sbjct: 171 TMGITVEGELRPGVTAKDIILAVIAKIGTGGGQGYVLEYRGSAIRALSMEGRMTVCNMSI 230 Query: 555 EAGGKNGVVPADETTFKY 608 EAG + G+V DETTF Y Sbjct: 231 EAGARAGMVAPDETTFAY 248
>LEU2_PSEU2 (Q4ZUZ6) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 474 Score = 110 bits (276), Expect = 2e-24 Identities = 55/148 (37%), Positives = 89/148 (60%) Frame = +3 Query: 165 LSDFRANPDYKGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFATGIGNTDAGFVMG 344 +++F+ N +G+ H+ ++G PG ++ DSHT GAFG A GIG ++ V+ Sbjct: 100 ITEFKMNDPRQGIVHVIGPEQGATLPGMSVVCGDSHTSTHGAFGALAHGIGTSEVEHVLA 159 Query: 345 TGKALLKVPPTIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTME 524 T + K + ++G++P + AKD++L +IG+I +G ++EF GS I L++E Sbjct: 160 TQCLVAKKMKNMLVSVEGQLPFGVTAKDIVLAVIGKIGTAGGNGYAIEFAGSAIRDLSIE 219 Query: 525 ERMTLCNMVIEAGGKNGVVPADETTFKY 608 RMT+CNM IEAG + G+V DE T +Y Sbjct: 220 GRMTICNMSIEAGARVGMVATDEKTVEY 247
>LEU2_PSE14 (Q48K99) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 474 Score = 110 bits (276), Expect = 2e-24 Identities = 55/148 (37%), Positives = 89/148 (60%) Frame = +3 Query: 165 LSDFRANPDYKGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFATGIGNTDAGFVMG 344 +++F+ N +G+ H+ ++G PG ++ DSHT GAFG A GIG ++ V+ Sbjct: 100 ITEFKMNDPRQGIVHVIGPEQGATLPGMSVVCGDSHTSTHGAFGALAHGIGTSEVEHVLA 159 Query: 345 TGKALLKVPPTIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTME 524 T + K + ++G++P + AKD++L +IG+I +G ++EF GS I L++E Sbjct: 160 TQCLVAKKMKNMLVSVEGQLPFGVTAKDIVLAVIGKIGTAGGNGYAIEFAGSAIRDLSIE 219 Query: 525 ERMTLCNMVIEAGGKNGVVPADETTFKY 608 RMT+CNM IEAG + G+V DE T +Y Sbjct: 220 GRMTICNMSIEAGARVGMVATDEKTVEY 247
>LEU2_PSEHT (Q3IJS4) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 466 Score = 110 bits (275), Expect = 3e-24 Identities = 54/138 (39%), Positives = 83/138 (60%) Frame = +3 Query: 195 KGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFATGIGNTDAGFVMGTGKALLKVPP 374 +G+ H+ ++G PG ++ DSHT GAFG A GIG ++ V+ T K Sbjct: 105 QGIVHVMGPEQGITLPGTTIVCGDSHTSTHGAFGALAHGIGTSEVEHVLATQTLQQKKAK 164 Query: 375 TIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVI 554 +++ ++G + P + AKDLI+ +IG++ +G T EF G IE+L+ME RMTLCNM I Sbjct: 165 SLKIQINGRLRPTVTAKDLIMAVIGKLGTAGGTGYVAEFCGEGIEALSMEARMTLCNMSI 224 Query: 555 EAGGKNGVVPADETTFKY 608 E G K G++ +D+ T+ Y Sbjct: 225 EMGAKAGLIASDQITYDY 242
>LEU2_NEIG1 (Q5F8T1) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 469 Score = 110 bits (275), Expect = 3e-24 Identities = 57/138 (41%), Positives = 81/138 (58%) Frame = +3 Query: 195 KGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFATGIGNTDAGFVMGTGKALLKVPP 374 +G+ H+ ++G PG ++ DSHT GAFG A GIG ++ M T K Sbjct: 107 QGIVHVMGPEQGATLPGMTVVCGDSHTSTHGAFGALAHGIGTSEVEHTMATQCITAKKSK 166 Query: 375 TIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVI 554 ++ DG++ + AKD+ L IIG+I +G T ++EF G I SL+ME RMTLCNM I Sbjct: 167 SMLIAADGKLKAGVTAKDVALYIIGQIGTAGGTGYAVEFGGEAIRSLSMEGRMTLCNMAI 226 Query: 555 EAGGKNGVVPADETTFKY 608 EAG ++G+V D+TT Y Sbjct: 227 EAGARSGMVAVDQTTIDY 244
>LEU2_PSEAE (Q9HZA3) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 474 Score = 110 bits (275), Expect = 3e-24 Identities = 54/148 (36%), Positives = 86/148 (58%) Frame = +3 Query: 165 LSDFRANPDYKGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFATGIGNTDAGFVMG 344 +++F+ N +G+ H+ ++G PG ++ DSHT GAFG A GIG ++ V+ Sbjct: 101 ITEFKMNDVRQGIVHVVGPEQGATLPGMTVVCGDSHTSTHGAFGALAHGIGTSEVEHVLA 160 Query: 345 TGKALLKVPPTIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTME 524 T + K + ++G +P + AKD++L +IG I +G ++EF GS I L++E Sbjct: 161 TQCLVAKKMKNMLVKVEGRLPAGVTAKDIVLAVIGRIGTAGGNGHAIEFAGSAIRDLSIE 220 Query: 525 ERMTLCNMVIEAGGKNGVVPADETTFKY 608 RMT+CNM IEAG + G+V D+ T Y Sbjct: 221 GRMTICNMSIEAGARVGLVAVDQKTIDY 248
>LEU2_GEOKA (Q5KWJ5) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 471 Score = 110 bits (274), Expect = 4e-24 Identities = 56/138 (40%), Positives = 81/138 (58%) Frame = +3 Query: 195 KGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFATGIGNTDAGFVMGTGKALLKVPP 374 +G+ H+ + G +PG+ ++ DSHT GAFG A GIG ++ V+ T P Sbjct: 105 QGIVHVIGPELGLTQPGKTIVCGDSHTSTHGAFGALAFGIGTSEVEHVLATQTLWQHKPK 164 Query: 375 TIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVI 554 T++ ++G + + AKD+IL IIG V T +EF G I ++MEERMT+CNM I Sbjct: 165 TLQICINGRLGKGVTAKDVILAIIGRYGVGVGTGYIIEFTGEAIRRMSMEERMTICNMSI 224 Query: 555 EAGGKNGVVPADETTFKY 608 EAG + G++ DETTF Y Sbjct: 225 EAGARAGLISPDETTFAY 242
>LEU2_BACCR (Q81G10) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 464 Score = 110 bits (274), Expect = 4e-24 Identities = 55/138 (39%), Positives = 80/138 (57%) Frame = +3 Query: 195 KGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFATGIGNTDAGFVMGTGKALLKVPP 374 +G+ H+ + G +PG+ ++ DSHT GAFG A GIG ++ V+ T + P Sbjct: 104 QGIVHVIGPELGLTQPGKTIVCGDSHTATHGAFGALAFGIGTSEVEHVLATQTLWQRKPK 163 Query: 375 TIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVI 554 + L G++P + AKD+IL ++ + V+ T MEF G I ++ MEERMTLCNM I Sbjct: 164 AMGIELKGKLPQGVYAKDIILHLLSKYGVAVGTGYVMEFYGEAIHAMDMEERMTLCNMAI 223 Query: 555 EAGGKNGVVPADETTFKY 608 E G K G++ DE TF Y Sbjct: 224 EGGAKAGIIAPDEKTFAY 241
>LEU2_METCA (Q606F2) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 470 Score = 109 bits (273), Expect = 5e-24 Identities = 55/148 (37%), Positives = 85/148 (57%) Frame = +3 Query: 165 LSDFRANPDYKGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFATGIGNTDAGFVMG 344 +++F + +G+ H+ ++G PG ++ DSHT GAFG A GIG ++ V+ Sbjct: 96 ITEFAMDDVRQGIVHVIGPEQGATLPGMTIVCGDSHTSTHGAFGALAFGIGTSEVEHVLA 155 Query: 345 TGKALLKVPPTIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTME 524 T + + + + G++ P + AKDL+L +IG I +G T ++EF G I L+ME Sbjct: 156 TQCLVQRKAKNMLVRVQGKLAPGVTAKDLVLAVIGRIGTAGGTGYTIEFAGEAIRGLSME 215 Query: 525 ERMTLCNMVIEAGGKNGVVPADETTFKY 608 RMT+CNM IEAG + G+V DE T Y Sbjct: 216 GRMTVCNMAIEAGARAGLVAVDEVTLDY 243
>LEU2_STAAR (Q6GF14) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 455 Score = 109 bits (273), Expect = 5e-24 Identities = 54/145 (37%), Positives = 83/145 (57%) Frame = +3 Query: 174 FRANPDYKGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFATGIGNTDAGFVMGTGK 353 F D +G+ H+ + G +PG+ ++ DSHT GAFG A GIG ++ V T Sbjct: 97 FDMGSDEQGIVHMVGPETGLTQPGKTIVCGDSHTATHGAFGAIAFGIGTSEVEHVFATQT 156 Query: 354 ALLKVPPTIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERM 533 P ++ ++G +P + AKD+IL +I V T ++EF G TI++L+M+ RM Sbjct: 157 LWQTKPKNLKIDINGTLPTGVYAKDIILHLIKTYGVDFGTGYALEFTGETIKNLSMDGRM 216 Query: 534 TLCNMVIEAGGKNGVVPADETTFKY 608 T+CNM IE G K G++ D+ TF+Y Sbjct: 217 TICNMAIEGGAKYGIIQPDDITFEY 241
>LEU2_BLOPB (Q493R2) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 466 Score = 109 bits (273), Expect = 5e-24 Identities = 62/167 (37%), Positives = 91/167 (54%), Gaps = 2/167 (1%) Frame = +3 Query: 114 GXFCQEQKIKYFYDIKD--LSDFRANPDYKGVCHIALAQEGHCRPGEVLLGTDSHTCNAG 287 G +EQ + + KD ++ F N Y+G+ H+ ++G PG ++ DSHT G Sbjct: 76 GSMAKEQLDRLTKNCKDFGITLFGLNHPYQGIVHVLAPEQGITLPGMTIVCGDSHTATHG 135 Query: 288 AFGQFATGIGNTDAGFVMGTGKALLKVPPTIRFVLDGEMPPYLLAKDLILQIIGEISVSG 467 AFG A GIG ++ V+ T +++ L G + P + AKD+IL IIG+I G Sbjct: 136 AFGALAFGIGTSEIEHVLATQTLQQIRYKSMQINLSGIIAPQITAKDIILAIIGKIGHGG 195 Query: 468 ATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGVVPADETTFKY 608 + +EF G I L+MEERMTLCNM IE G + ++ D TT+ Y Sbjct: 196 GSGHVVEFCGPIITLLSMEERMTLCNMAIEMGATSALIAPDRTTYDY 242
>LEU22_BRAJA (Q89X34) 3-isopropylmalate dehydratase large subunit 2 (EC| 4.2.1.33) (Isopropylmalate isomerase 2) (Alpha-IPM isomerase 2) (IPMI 2) Length = 468 Score = 109 bits (273), Expect = 5e-24 Identities = 53/138 (38%), Positives = 81/138 (58%) Frame = +3 Query: 195 KGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFATGIGNTDAGFVMGTGKALLKVPP 374 +G+ H+ ++G PG ++ DSHT GAFG A GIG ++ V+ T + K Sbjct: 107 QGIVHVIGPEQGFTLPGTTIVCGDSHTSTHGAFGALAHGIGTSEVEHVLATQTLIQKKAK 166 Query: 375 TIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVI 554 +R +DG++P + KD+IL IIGEI +G T +E+ G I +L+ME RMT+CNM I Sbjct: 167 NMRVTVDGKLPDGVTGKDIILAIIGEIGTAGGTGYVLEYAGEAIRALSMEGRMTVCNMSI 226 Query: 555 EAGGKNGVVPADETTFKY 608 E G + G+V D+ + + Sbjct: 227 EGGARAGLVAPDQKAYDF 244
>LEU2_ZYMMO (Q5NRC5) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 484 Score = 109 bits (273), Expect = 5e-24 Identities = 55/138 (39%), Positives = 83/138 (60%) Frame = +3 Query: 195 KGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFATGIGNTDAGFVMGTGKALLKVPP 374 +G+ H+ ++G PG L+ DSHT GA G A GIG ++ VM T +L Sbjct: 114 QGIVHVVGPEQGFTLPGTTLVCGDSHTAAHGALGALAFGIGTSEVEHVMATQTLILTPAK 173 Query: 375 TIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVI 554 T+ ++G++ P + AKDLIL II + +G T ++E+ G I +L++EER+T+ NM I Sbjct: 174 TMEVRVEGKLSPDVSAKDLILHIIHSLGTAGGTGYAIEYTGEAIRNLSIEERLTVSNMSI 233 Query: 555 EAGGKNGVVPADETTFKY 608 EAG + G++ ADE TF Y Sbjct: 234 EAGARTGLIAADEKTFAY 251
>LEU2_PSEF5 (Q4KF08) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 472 Score = 109 bits (273), Expect = 5e-24 Identities = 56/146 (38%), Positives = 86/146 (58%) Frame = +3 Query: 171 DFRANPDYKGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFATGIGNTDAGFVMGTG 350 +F+ N +G+ H+ ++G PG ++ DSHT GAFG A GIG ++ V+ T Sbjct: 102 EFKMNDVRQGIVHVIGPEQGATLPGMTVVCGDSHTSTHGAFGALAHGIGTSEVEHVLATQ 161 Query: 351 KALLKVPPTIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEER 530 + K + ++G +P + AKD++L +IG+I +G ++EF GS I L++E R Sbjct: 162 CLVAKKMKNMLVRVEGTLPFGVTAKDIVLAVIGKIGTAGGNGHAIEFAGSAIRELSVEGR 221 Query: 531 MTLCNMVIEAGGKNGVVPADETTFKY 608 MT+CNM IEAG + G+V ADE T Y Sbjct: 222 MTICNMSIEAGARVGLVAADEKTVAY 247
>LEU2_STAAW (P58947) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 456 Score = 109 bits (273), Expect = 5e-24 Identities = 54/145 (37%), Positives = 83/145 (57%) Frame = +3 Query: 174 FRANPDYKGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFATGIGNTDAGFVMGTGK 353 F D +G+ H+ + G +PG+ ++ DSHT GAFG A GIG ++ V T Sbjct: 97 FDMGSDEQGIVHMVGPETGLTQPGKTIVCGDSHTATHGAFGAIAFGIGTSEVEHVFATQT 156 Query: 354 ALLKVPPTIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERM 533 P ++ ++G +P + AKD+IL +I V T ++EF G TI++L+M+ RM Sbjct: 157 LWQTKPKNLKIDINGTLPTGVYAKDIILHLIKTYGVDFGTGYALEFTGETIKNLSMDGRM 216 Query: 534 TLCNMVIEAGGKNGVVPADETTFKY 608 T+CNM IE G K G++ D+ TF+Y Sbjct: 217 TICNMAIEGGAKYGIIQPDDITFEY 241
>LEU2_STAAS (Q6G7P9) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 456 Score = 109 bits (273), Expect = 5e-24 Identities = 54/145 (37%), Positives = 83/145 (57%) Frame = +3 Query: 174 FRANPDYKGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFATGIGNTDAGFVMGTGK 353 F D +G+ H+ + G +PG+ ++ DSHT GAFG A GIG ++ V T Sbjct: 97 FDMGSDEQGIVHMVGPETGLTQPGKTIVCGDSHTATHGAFGAIAFGIGTSEVEHVFATQT 156 Query: 354 ALLKVPPTIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERM 533 P ++ ++G +P + AKD+IL +I V T ++EF G TI++L+M+ RM Sbjct: 157 LWQTKPKNLKIDINGTLPTGVYAKDIILHLIKTYGVDFGTGYALEFTGETIKNLSMDGRM 216 Query: 534 TLCNMVIEAGGKNGVVPADETTFKY 608 T+CNM IE G K G++ D+ TF+Y Sbjct: 217 TICNMAIEGGAKYGIIQPDDITFEY 241
>LEU2_STAAN (P63436) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 456 Score = 109 bits (273), Expect = 5e-24 Identities = 54/145 (37%), Positives = 83/145 (57%) Frame = +3 Query: 174 FRANPDYKGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFATGIGNTDAGFVMGTGK 353 F D +G+ H+ + G +PG+ ++ DSHT GAFG A GIG ++ V T Sbjct: 97 FDMGSDEQGIVHMVGPETGLTQPGKTIVCGDSHTATHGAFGAIAFGIGTSEVEHVFATQT 156 Query: 354 ALLKVPPTIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERM 533 P ++ ++G +P + AKD+IL +I V T ++EF G TI++L+M+ RM Sbjct: 157 LWQTKPKNLKIDINGTLPTGVYAKDIILHLIKTYGVDFGTGYALEFTGETIKNLSMDGRM 216 Query: 534 TLCNMVIEAGGKNGVVPADETTFKY 608 T+CNM IE G K G++ D+ TF+Y Sbjct: 217 TICNMAIEGGAKYGIIQPDDITFEY 241
>LEU2_STAAM (P63435) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 456 Score = 109 bits (273), Expect = 5e-24 Identities = 54/145 (37%), Positives = 83/145 (57%) Frame = +3 Query: 174 FRANPDYKGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFATGIGNTDAGFVMGTGK 353 F D +G+ H+ + G +PG+ ++ DSHT GAFG A GIG ++ V T Sbjct: 97 FDMGSDEQGIVHMVGPETGLTQPGKTIVCGDSHTATHGAFGAIAFGIGTSEVEHVFATQT 156 Query: 354 ALLKVPPTIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERM 533 P ++ ++G +P + AKD+IL +I V T ++EF G TI++L+M+ RM Sbjct: 157 LWQTKPKNLKIDINGTLPTGVYAKDIILHLIKTYGVDFGTGYALEFTGETIKNLSMDGRM 216 Query: 534 TLCNMVIEAGGKNGVVPADETTFKY 608 T+CNM IE G K G++ D+ TF+Y Sbjct: 217 TICNMAIEGGAKYGIIQPDDITFEY 241
>LEU2_STAAC (Q5HEE2) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 456 Score = 109 bits (273), Expect = 5e-24 Identities = 54/145 (37%), Positives = 83/145 (57%) Frame = +3 Query: 174 FRANPDYKGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFATGIGNTDAGFVMGTGK 353 F D +G+ H+ + G +PG+ ++ DSHT GAFG A GIG ++ V T Sbjct: 97 FDMGSDEQGIVHMVGPETGLTQPGKTIVCGDSHTATHGAFGAIAFGIGTSEVEHVFATQT 156 Query: 354 ALLKVPPTIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERM 533 P ++ ++G +P + AKD+IL +I V T ++EF G TI++L+M+ RM Sbjct: 157 LWQTKPKNLKIDINGTLPTGVYAKDIILHLIKTYGVDFGTGYALEFTGETIKNLSMDGRM 216 Query: 534 TLCNMVIEAGGKNGVVPADETTFKY 608 T+CNM IE G K G++ D+ TF+Y Sbjct: 217 TICNMAIEGGAKYGIIQPDDITFEY 241
>LEU2_BUCDN (O85072) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 466 Score = 109 bits (272), Expect = 7e-24 Identities = 56/148 (37%), Positives = 89/148 (60%) Frame = +3 Query: 165 LSDFRANPDYKGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFATGIGNTDAGFVMG 344 +S + N +G+ H+ ++G PG V++ DSHT GAFG + GIG ++ V+ Sbjct: 95 ISLYDLNHPNQGIVHVISPEQGMTLPGMVIVCGDSHTSTHGAFGALSFGIGTSEVEHVLA 154 Query: 345 TGKALLKVPPTIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTME 524 T + ++ + G++ ++ AKD+IL IIG+I S T +EF G+ I+ ++ME Sbjct: 155 TQTLKQQRFKNMKIEVIGKIGNFITAKDVILYIIGKIGSSAGTGYIIEFCGNVIKKMSME 214 Query: 525 ERMTLCNMVIEAGGKNGVVPADETTFKY 608 ERMT+CNM IE G K+G++ DETT+ Y Sbjct: 215 ERMTVCNMAIELGAKSGLIAPDETTYLY 242
>LEU2_VIBCH (Q9KP81) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 467 Score = 109 bits (272), Expect = 7e-24 Identities = 56/142 (39%), Positives = 81/142 (57%) Frame = +3 Query: 183 NPDYKGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFATGIGNTDAGFVMGTGKALL 362 N Y+G+ H+ + G PG ++ DSHT GAFG A GIG ++ V+ T Sbjct: 103 NHKYQGIVHVMGPELGITLPGMTIVCGDSHTATHGAFGSLAFGIGTSEVEHVLATQTLKQ 162 Query: 363 KVPPTIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLC 542 T++ + G++ P + AKD++L IIG+ + +G T +EF G I L+ME RMT+C Sbjct: 163 GRAKTMKIEVRGKVAPGITAKDIVLAIIGKTTAAGGTGYVVEFCGEAIRDLSMEGRMTVC 222 Query: 543 NMVIEAGGKNGVVPADETTFKY 608 NM IE G K G++ D TTF Y Sbjct: 223 NMAIELGAKAGLIAPDATTFNY 244
>LEU2_BUCML (Q9EVG2) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) (Fragment) Length = 442 Score = 109 bits (272), Expect = 7e-24 Identities = 56/161 (34%), Positives = 96/161 (59%) Frame = +3 Query: 126 QEQKIKYFYDIKDLSDFRANPDYKGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFA 305 Q ++++ D ++S + N +G+ H+ ++G PG ++ DSHT GAFG + Sbjct: 82 QMEQLRKNCDEFNISLYDINNPNQGIVHVIAPEKGMTLPGMTIVCGDSHTSTHGAFGALS 141 Query: 306 TGIGNTDAGFVMGTGKALLKVPPTIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSM 485 GIG ++ V+ T + ++ + G++P ++ AKD+IL IIG+ S + + Sbjct: 142 FGIGTSEVEHVLATQTLKQQRFKNMKIEIIGQIPKFISAKDIILFIIGKXGSSIGSGYVV 201 Query: 486 EFVGSTIESLTMEERMTLCNMVIEAGGKNGVVPADETTFKY 608 EF G+ IE+++MEERMT+CNM IE G K+G++ D+TT+ Y Sbjct: 202 EFCGNVIETMSMEERMTICNMAIEMGAKSGLIAPDKTTYAY 242
>LEU2_SHEON (Q8E9N4) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 474 Score = 109 bits (272), Expect = 7e-24 Identities = 57/138 (41%), Positives = 82/138 (59%) Frame = +3 Query: 195 KGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFATGIGNTDAGFVMGTGKALLKVPP 374 +G+ H+ + G PG V++ DSHT GAFG A GIG ++ V+ T Sbjct: 113 QGIVHVMGPELGITLPGTVIVCGDSHTATHGAFGALAFGIGTSEVEHVLATQTLRQLKAK 172 Query: 375 TIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVI 554 T++ + G++ + AKD++L IIG+I + G T +EF G IE+L+ME RMT+CNM I Sbjct: 173 TMKIEVRGQVTDGVTAKDIVLAIIGKIGMDGGTGYVVEFCGEAIEALSMEGRMTVCNMAI 232 Query: 555 EAGGKNGVVPADETTFKY 608 E G K G+V D+TTF Y Sbjct: 233 EMGAKAGMVAPDQTTFDY 250
>LEU2_COREF (Q8FPR3) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 481 Score = 108 bits (271), Expect = 9e-24 Identities = 58/138 (42%), Positives = 80/138 (57%) Frame = +3 Query: 195 KGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFATGIGNTDAGFVMGTGKALLKVPP 374 +G+ H Q G +PG ++ DSHT GAFG A GIG ++ VM T LK Sbjct: 121 QGIVHTVGPQLGATQPGMTIVCGDSHTSTHGAFGAMAFGIGTSEVEHVMATQTLPLKPFK 180 Query: 375 TIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVI 554 T+ + GE+ P + +KDLIL II +I G +E+ G I L+M+ RMT+CNM I Sbjct: 181 TMAIEVTGELQPGVSSKDLILAIIAKIGTGGGQGYVLEYRGEAIRKLSMDARMTICNMSI 240 Query: 555 EAGGKNGVVPADETTFKY 608 EAG + G++ DETTF+Y Sbjct: 241 EAGARAGMIAPDETTFEY 258
>LEU2_PHOPR (Q6LV26) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 476 Score = 108 bits (271), Expect = 9e-24 Identities = 55/142 (38%), Positives = 82/142 (57%) Frame = +3 Query: 183 NPDYKGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFATGIGNTDAGFVMGTGKALL 362 N Y+G+ H+ + G PG ++ DSHT GAFG A GIG ++ V+ T Sbjct: 107 NHKYQGIVHVIGPELGITLPGMTIVCGDSHTATHGAFGSLAFGIGTSEVEHVLATQTLKQ 166 Query: 363 KVPPTIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLC 542 + T++ + G++ + AKD++L IIG+ + +G T +EF G I LTME RMT+C Sbjct: 167 SLAKTMKIEVVGKVAEGITAKDIVLAIIGKTTAAGGTGYVVEFCGEAITDLTMEGRMTVC 226 Query: 543 NMVIEAGGKNGVVPADETTFKY 608 NM IE G K G++ D+TT+ Y Sbjct: 227 NMAIELGAKAGLIAPDQTTYDY 248
>LEU2_BUCPS (P58945) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 465 Score = 108 bits (271), Expect = 9e-24 Identities = 62/162 (38%), Positives = 89/162 (54%) Frame = +3 Query: 123 CQEQKIKYFYDIKDLSDFRANPDYKGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQF 302 C++ IK YDI N ++G+ H+ ++G PG V++ DSHT GAFG Sbjct: 90 CKDFNIK-LYDI--------NHPHQGIVHVLGPEKGMTLPGMVIVCGDSHTSTHGAFGAL 140 Query: 303 ATGIGNTDAGFVMGTGKALLKVPPTIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRS 482 A GIG ++ V+ T T+ + G + P + AKD+IL II ++S SG Sbjct: 141 AFGIGTSEVEHVLATQTLQQNRLKTMNIEITGNINPMVFAKDIILSIIRKLSTSGGIGYV 200 Query: 483 MEFVGSTIESLTMEERMTLCNMVIEAGGKNGVVPADETTFKY 608 +EF GS I L+ME RMT+CNM IE G K+G++ D T+ Y Sbjct: 201 IEFSGSVISQLSMESRMTICNMSIEMGAKSGLIAPDIITYNY 242
>LEU2_PSYAR (Q4FRU7) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 472 Score = 108 bits (271), Expect = 9e-24 Identities = 54/149 (36%), Positives = 86/149 (57%) Frame = +3 Query: 162 DLSDFRANPDYKGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFATGIGNTDAGFVM 341 D+++F N +G+ H+ ++G PG ++ DSHT GA G A GIG ++ V+ Sbjct: 100 DIAEFTINDARQGILHVVGPEQGLVLPGMTVVCGDSHTATHGALGCLAHGIGTSEVEHVL 159 Query: 342 GTGKALLKVPPTIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTM 521 T + K ++ + GE+ + +KD++L II +I +G T ++EF G E ++M Sbjct: 160 ATQCLIQKKSKNMQIRVTGELGVGVTSKDVVLAIIAKIGTAGGTGHAIEFAGQVFEDMSM 219 Query: 522 EERMTLCNMVIEAGGKNGVVPADETTFKY 608 E RMT+CNM IEAG + G+V D+TT Y Sbjct: 220 EGRMTVCNMAIEAGARVGMVAVDDTTINY 248
>LEU2_VIBVU (Q8DED9) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 466 Score = 108 bits (270), Expect = 1e-23 Identities = 61/162 (37%), Positives = 88/162 (54%) Frame = +3 Query: 123 CQEQKIKYFYDIKDLSDFRANPDYKGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQF 302 CQE + YDI N Y+G+ H+ + G PG ++ DSHT GAFG Sbjct: 90 CQEFGVT-LYDI--------NHKYQGIVHVMGPELGITLPGMTIVCGDSHTATHGAFGSL 140 Query: 303 ATGIGNTDAGFVMGTGKALLKVPPTIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRS 482 A GIG ++ V+ T T++ + G++ + AKD++L IIG+ + +G T Sbjct: 141 AFGIGTSEVEHVLATQTLKQARAKTMKIEVQGKVADGITAKDIVLAIIGKTTAAGGTGYV 200 Query: 483 MEFVGSTIESLTMEERMTLCNMVIEAGGKNGVVPADETTFKY 608 +EF G I L+ME RMT+CNM IE G K G++ D+TTF Y Sbjct: 201 VEFCGEAITDLSMEGRMTVCNMAIELGAKAGLIAPDQTTFDY 242
>LEU2_VIBF1 (Q5E858) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 471 Score = 108 bits (270), Expect = 1e-23 Identities = 56/142 (39%), Positives = 81/142 (57%) Frame = +3 Query: 183 NPDYKGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFATGIGNTDAGFVMGTGKALL 362 N Y+G+ H+ + G PG ++ DSHT GAFG A GIG ++ V+ T Sbjct: 103 NHKYQGIVHVMGPELGITLPGMTIVCGDSHTATHGAFGSLAFGIGTSEVEHVLATQTLKQ 162 Query: 363 KVPPTIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLC 542 T++ + G++ + AKD++L IIG+ + +G T +EF G I LTME RMT+C Sbjct: 163 ARAKTMKIDVKGKVAEGITAKDIVLAIIGKTTAAGGTGYVVEFCGEAITDLTMEGRMTVC 222 Query: 543 NMVIEAGGKNGVVPADETTFKY 608 NM IE G K G++ D+TTF Y Sbjct: 223 NMAIELGAKAGLIAPDQTTFDY 244
>LEU22_METKA (Q8TW29) 3-isopropylmalate dehydratase large subunit 2 (EC| 4.2.1.33) (Isopropylmalate isomerase 2) (Alpha-IPM isomerase 2) (IPMI 2) Length = 402 Score = 108 bits (270), Expect = 1e-23 Identities = 54/133 (40%), Positives = 78/133 (58%) Frame = +3 Query: 195 KGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFATGIGNTDAGFVMGTGKALLKVPP 374 +GVCH L +EG+ PG V+ G DSHT +GA A G G TD F + G+ ++VP Sbjct: 96 EGVCHQVLVEEGYAGPGRVVFGGDSHTPTSGAASALAFGFGGTDMAFALLYGELWIRVPR 155 Query: 375 TIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVI 554 T+R ++GE+ AKDL L ++GE+ A Y +E+ G E +++ +RM LCN+ Sbjct: 156 TVRVHVEGELEEPATAKDLALTVVGELGAGYADYAVLEYTGLP-ERMSLGDRMCLCNLAT 214 Query: 555 EAGGKNGVVPADE 593 EAG K+ VP E Sbjct: 215 EAGAKSAYVPPKE 227
>LEU2_CORJK (Q4JUX2) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 473 Score = 108 bits (269), Expect = 2e-23 Identities = 57/138 (41%), Positives = 79/138 (57%) Frame = +3 Query: 195 KGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFATGIGNTDAGFVMGTGKALLKVPP 374 +G+ H Q G +PG ++ DSHT GAFG A GIG ++ V+ T LK Sbjct: 113 QGIVHTVGPQLGLTQPGMTVVCGDSHTSTHGAFGSIAMGIGTSEVEHVLATQTLPLKPFK 172 Query: 375 TIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVI 554 T+ + GE+ P + +KDLIL II +I G +E+ G IE L+ME RMT+CNM I Sbjct: 173 TMAIEVSGELQPDVTSKDLILAIIAKIGTGGGQGHIIEYRGEAIEKLSMEARMTMCNMSI 232 Query: 555 EAGGKNGVVPADETTFKY 608 EAG + G++ D+ TF Y Sbjct: 233 EAGARAGMIAPDQVTFDY 250
>LEU2_VIBVY (Q7MP79) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 466 Score = 108 bits (269), Expect = 2e-23 Identities = 61/162 (37%), Positives = 88/162 (54%) Frame = +3 Query: 123 CQEQKIKYFYDIKDLSDFRANPDYKGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQF 302 CQE + YDI N Y+G+ H+ + G PG ++ DSHT GAFG Sbjct: 90 CQEFGVT-LYDI--------NHKYQGIVHVMGPELGITLPGMTIVCGDSHTATHGAFGSL 140 Query: 303 ATGIGNTDAGFVMGTGKALLKVPPTIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRS 482 A GIG ++ V+ T T++ + G++ + AKD++L IIG+ + +G T Sbjct: 141 AFGIGTSEVEHVLATQTLKQARAKTMKIEVQGKVADGITAKDIVLAIIGKTTAAGGTGYV 200 Query: 483 MEFVGSTIESLTMEERMTLCNMVIEAGGKNGVVPADETTFKY 608 +EF G I L+ME RMT+CNM IE G K G++ D+TTF Y Sbjct: 201 VEFCGEAITDLSMEGRMTVCNMAIELGAKAGLIAPDKTTFDY 242
>LEU2_BIFLO (Q8G4W2) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 467 Score = 108 bits (269), Expect = 2e-23 Identities = 58/138 (42%), Positives = 81/138 (58%) Frame = +3 Query: 195 KGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFATGIGNTDAGFVMGTGKALLKVPP 374 +G+ H G +PG ++ DSHT GAFG A GIG ++ VM T LK Sbjct: 106 QGIVHAFAPILGLTQPGMTIVCGDSHTSTHGAFGALAFGIGTSEVEHVMATQTLSLKPFK 165 Query: 375 TIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVI 554 T+ ++G++P AKD+IL II +I G +E+ G I +LTM+ERMT+CNM I Sbjct: 166 TMAVNVNGKLPADATAKDIILAIIAKIGTGGGQGYVIEYRGEAIRNLTMDERMTVCNMSI 225 Query: 555 EAGGKNGVVPADETTFKY 608 EAG + G++ DETTF+Y Sbjct: 226 EAGARAGMIAPDETTFEY 243
>LEU2_BACCZ (Q63DX6) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 464 Score = 108 bits (269), Expect = 2e-23 Identities = 55/138 (39%), Positives = 80/138 (57%) Frame = +3 Query: 195 KGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFATGIGNTDAGFVMGTGKALLKVPP 374 +G+ H+ + G +PG+ ++ DSHT GAFG A GIG ++ V+ T + P Sbjct: 104 QGIVHVIGPELGLTQPGKTIVCGDSHTATHGAFGALAFGIGTSEVEHVLATQTLWQRKPK 163 Query: 375 TIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVI 554 + L G++ + AKD+IL ++ + V+ T MEF G TI ++ MEERMTLCNM I Sbjct: 164 AMGIELKGKLQKGVYAKDIILHLLSKYGVAVGTGYVMEFYGETIGAMEMEERMTLCNMAI 223 Query: 555 EAGGKNGVVPADETTFKY 608 E G K G++ DE TF Y Sbjct: 224 EGGAKAGIIAPDEKTFAY 241
>LEU2_BACAN (Q81T66) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 464 Score = 108 bits (269), Expect = 2e-23 Identities = 55/138 (39%), Positives = 80/138 (57%) Frame = +3 Query: 195 KGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFATGIGNTDAGFVMGTGKALLKVPP 374 +G+ H+ + G +PG+ ++ DSHT GAFG A GIG ++ V+ T + P Sbjct: 104 QGIVHVIGPELGLTQPGKTIVCGDSHTATHGAFGALAFGIGTSEVEHVLATQTLWQRKPK 163 Query: 375 TIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVI 554 + L G++ + AKD+IL ++ + V+ T MEF G TI ++ MEERMTLCNM I Sbjct: 164 AMGIELKGKLQKGVYAKDIILHLLSKYGVAVGTGYVMEFYGETIGTMEMEERMTLCNMAI 223 Query: 555 EAGGKNGVVPADETTFKY 608 E G K G++ DE TF Y Sbjct: 224 EGGAKAGIIAPDEKTFAY 241
>LEU2_BACSK (Q5WEN5) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 470 Score = 107 bits (268), Expect = 2e-23 Identities = 56/137 (40%), Positives = 77/137 (56%) Frame = +3 Query: 198 GVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFATGIGNTDAGFVMGTGKALLKVPPT 377 G+ H+ + G +PG V++ DSHT GAFG A GIG ++ V+ T P T Sbjct: 105 GIVHVIGPELGLTQPGHVIVCGDSHTSTHGAFGAIAFGIGTSEVEHVLATQTIWQSKPKT 164 Query: 378 IRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIE 557 + + G + + AKD+IL II + V T +EF G I +TMEERMT+CNM IE Sbjct: 165 LEVHISGRLNEGISAKDVILAIIAKFGVDIGTGSIIEFTGEAIRGMTMEERMTICNMSIE 224 Query: 558 AGGKNGVVPADETTFKY 608 AG K G++ D+ TF Y Sbjct: 225 AGAKAGLISPDQVTFDY 241
>LEU2_COLP3 (Q47WG2) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 471 Score = 107 bits (268), Expect = 2e-23 Identities = 56/138 (40%), Positives = 81/138 (58%) Frame = +3 Query: 195 KGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFATGIGNTDAGFVMGTGKALLKVPP 374 +G+ H+ + G PG +++ DSHT GAFG A GIG ++ V T Sbjct: 109 QGIAHVIGPELGLTLPGTIIVCGDSHTATHGAFGALAFGIGTSEVEHVFATQTLRQNKAK 168 Query: 375 TIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVI 554 T++ + G + + AKD+IL IIG+ +GAT +E+ G IE+L+MEERMT+CNM I Sbjct: 169 TMKIEVKGHVGAGISAKDIILAIIGKTGSAGATGYVVEYCGEAIEALSMEERMTVCNMSI 228 Query: 555 EAGGKNGVVPADETTFKY 608 E G K G++ D+TTF Y Sbjct: 229 EFGAKAGLIAPDQTTFDY 246
>LEU2_BUCUD (Q9EVE0) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) (Fragment) Length = 444 Score = 107 bits (268), Expect = 2e-23 Identities = 60/162 (37%), Positives = 93/162 (57%) Frame = +3 Query: 123 CQEQKIKYFYDIKDLSDFRANPDYKGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQF 302 CQE I YDI NP+ +G+ H+ ++G PG ++ DSHT GAFG Sbjct: 91 CQEFNIP-LYDIN-------NPN-QGIVHVIAPEKGMTLPGMTIVCGDSHTSTHGAFGAL 141 Query: 303 ATGIGNTDAGFVMGTGKALLKVPPTIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRS 482 A GIG ++ V+ T K ++ + G++P ++ AKD+IL +IG++ S T Sbjct: 142 AFGIGTSEVEHVLATQTLKQKRFKNMKIEIIGKIPKFVTAKDIILFVIGQLGSSSGTGYV 201 Query: 483 MEFVGSTIESLTMEERMTLCNMVIEAGGKNGVVPADETTFKY 608 +EF G+ I++++MEERMT+CNM IE K+G++ T+KY Sbjct: 202 IEFCGNIIKNMSMEERMTVCNMAIEMXAKSGLIAPXXITYKY 243
>LEU2_BACHK (Q6HLF1) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 464 Score = 107 bits (268), Expect = 2e-23 Identities = 55/138 (39%), Positives = 80/138 (57%) Frame = +3 Query: 195 KGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFATGIGNTDAGFVMGTGKALLKVPP 374 +G+ H+ + G +PG+ ++ DSHT GAFG A GIG ++ V+ T + P Sbjct: 104 QGIVHVIGPELGLTQPGKTIVCGDSHTATHGAFGALAFGIGTSEVEHVLATQTLWQRKPK 163 Query: 375 TIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVI 554 + L G++ + AKD+IL ++ + V+ T MEF G TI ++ MEERMTLCNM I Sbjct: 164 AMGIELKGKLQKGVYAKDIILHLLSKYGVAVGTGYVMEFYGETIGAMEMEERMTLCNMAI 223 Query: 555 EAGGKNGVVPADETTFKY 608 E G K G++ DE TF Y Sbjct: 224 EGGAKAGIIAPDEKTFVY 241
>LEU2_NOCFA (Q5YRY0) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 474 Score = 107 bits (268), Expect = 2e-23 Identities = 51/138 (36%), Positives = 83/138 (60%) Frame = +3 Query: 195 KGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFATGIGNTDAGFVMGTGKALLKVPP 374 +G+ H+ Q G +PG ++ DSHT GAFG A GIG ++ V+ T L+ Sbjct: 113 QGIVHVVGPQLGLTQPGMTVVCGDSHTSTHGAFGALAMGIGTSEVEHVLATQTLSLRPFK 172 Query: 375 TIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVI 554 T+ +DG++PP + +KD+IL +I +I G +E+ G + +++ME RMT+CNM I Sbjct: 173 TMAINIDGQLPPGVTSKDVILAVIAQIGTGGGQGYVLEYRGEAVRAMSMEARMTMCNMSI 232 Query: 555 EAGGKNGVVPADETTFKY 608 EAG + G++ DE T+++ Sbjct: 233 EAGARAGMIAPDEVTYEF 250
>LEU22_SALTY (Q8ZRJ0) 3-isopropylmalate dehydratase large subunit 2 (EC| 4.2.1.33) (Isopropylmalate isomerase 2) (Alpha-IPM isomerase 2) (IPMI 2) Length = 473 Score = 107 bits (267), Expect = 3e-23 Identities = 51/138 (36%), Positives = 81/138 (58%) Frame = +3 Query: 195 KGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFATGIGNTDAGFVMGTGKALLKVPP 374 +G+ H+ ++G PG V+ DSHT GAFG GIG ++ ++ T + + Sbjct: 108 QGIEHVVAHEQGLVMPGMVIAAGDSHTTTYGAFGALGFGIGTSEIEHLLATQTLVYRKLK 167 Query: 375 TIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVI 554 T+R + GE+P AKD++L+++ I GAT ++EFVG I +L++E RMTLCNM + Sbjct: 168 TMRVSVQGELPFACSAKDIVLELLERIGADGATGYAIEFVGEAISALSVEGRMTLCNMAV 227 Query: 555 EAGGKNGVVPADETTFKY 608 EAG + ++ D+ F Y Sbjct: 228 EAGARGAIIAPDKKVFDY 245
>LEU22_SALCH (Q57SN1) 3-isopropylmalate dehydratase large subunit 2 (EC| 4.2.1.33) (Isopropylmalate isomerase 2) (Alpha-IPM isomerase 2) (IPMI 2) Length = 473 Score = 107 bits (267), Expect = 3e-23 Identities = 51/138 (36%), Positives = 81/138 (58%) Frame = +3 Query: 195 KGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFATGIGNTDAGFVMGTGKALLKVPP 374 +G+ H+ ++G PG V+ DSHT GAFG GIG ++ ++ T + + Sbjct: 108 QGIEHVVAHEQGLVMPGMVIAAGDSHTTTYGAFGALGFGIGTSEIEHLLATQTLVYRKLK 167 Query: 375 TIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVI 554 T+R + GE+P AKD++L+++ I GAT ++EFVG I +L++E RMTLCNM + Sbjct: 168 TMRVSVQGELPFACSAKDIVLELLERIGADGATGYAIEFVGEAISALSVEGRMTLCNMAV 227 Query: 555 EAGGKNGVVPADETTFKY 608 EAG + ++ D+ F Y Sbjct: 228 EAGARGAIIAPDKKVFDY 245
>LEU2_BLOFL (Q7VQJ8) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 466 Score = 107 bits (267), Expect = 3e-23 Identities = 57/145 (39%), Positives = 84/145 (57%) Frame = +3 Query: 174 FRANPDYKGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFATGIGNTDAGFVMGTGK 353 F + ++G+ H+ ++G PG ++ DSHT GAFG + GIG ++ V+ T Sbjct: 98 FDLSHPHQGIIHVLAPEQGIILPGMTVVCGDSHTSTHGAFGALSFGIGTSEIEHVLVTQT 157 Query: 354 ALLKVPPTIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERM 533 ++ L G +PPY+ AKDLIL IIG+I GA+ +EF G I +L+MEERM Sbjct: 158 LRQPKYKSMGINLFGTIPPYITAKDLILFIIGKIGHGGASGYIVEFYGDVINTLSMEERM 217 Query: 534 TLCNMVIEAGGKNGVVPADETTFKY 608 T+CNM IE G + ++ D TT+ Y Sbjct: 218 TICNMSIEMGAASALIAPDVTTYNY 242
>LEU2_OCEIH (Q8EN69) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 468 Score = 107 bits (266), Expect = 4e-23 Identities = 58/142 (40%), Positives = 83/142 (58%) Frame = +3 Query: 183 NPDYKGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFATGIGNTDAGFVMGTGKALL 362 +PD +G+ H+ Q G +PG+ ++ DSHT GAFG A GIG ++ V+ T Sbjct: 103 HPD-QGIVHVIGPQLGLTQPGKTIVCGDSHTSTHGAFGALAFGIGTSEVEHVLATQTIWQ 161 Query: 363 KVPPTIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLC 542 P T+ + GE+ + AKDLIL II + V T ME+ G +I ++MEERMT+C Sbjct: 162 DKPKTLNVKVIGELGIGVTAKDLILAIIAKFGVQFGTGYVMEYTGESIRKMSMEERMTIC 221 Query: 543 NMVIEAGGKNGVVPADETTFKY 608 NM IEAG + G++ D+TT Y Sbjct: 222 NMSIEAGARAGLISPDQTTVDY 243
>LEU2_HAEIN (P44968) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 468 Score = 107 bits (266), Expect = 4e-23 Identities = 54/138 (39%), Positives = 82/138 (59%) Frame = +3 Query: 195 KGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFATGIGNTDAGFVMGTGKALLKVPP 374 +G+ H+ ++G PG ++ DSHT GAFG A GIG ++ V+ T Sbjct: 104 QGIVHVMGPEQGLTLPGMTIVCGDSHTATHGAFGALAFGIGTSEVEHVLATQTLKQARAK 163 Query: 375 TIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVI 554 +++ + G++ + AKD+IL IIG+ +++G T +EF G I+ L+ME RMT+CNM I Sbjct: 164 SMKIEVRGKVASGITAKDIILAIIGKTTMAGGTGHVVEFCGEAIQDLSMEGRMTVCNMAI 223 Query: 555 EAGGKNGVVPADETTFKY 608 E G K G++ DETTF Y Sbjct: 224 EMGAKAGLIAPDETTFAY 241
>LEU2_BACTN (Q8A6L7) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 464 Score = 107 bits (266), Expect = 4e-23 Identities = 54/137 (39%), Positives = 81/137 (59%) Frame = +3 Query: 198 GVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFATGIGNTDAGFVMGTGKALLKVPPT 377 G+ H+ + PG ++ DSHT GA G A GIG ++ V+ + L P T Sbjct: 105 GIIHVVGPERALTLPGMTIVCGDSHTSTHGAMGAIAFGIGTSEVEMVLASQCILQSRPKT 164 Query: 378 IRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIE 557 +R +DGE+ + AKD+ L ++ +++ SGAT +E+ GS I +LTME R+TLCN+ IE Sbjct: 165 MRITVDGELGKGVTAKDVALYMMSKMTTSGATGYFVEYAGSAIRNLTMEGRLTLCNLSIE 224 Query: 558 AGGKNGVVPADETTFKY 608 G + G+V DE TF+Y Sbjct: 225 MGARGGMVAPDEVTFEY 241
>LEU2_BACFR (Q64QP1) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 464 Score = 107 bits (266), Expect = 4e-23 Identities = 53/137 (38%), Positives = 81/137 (59%) Frame = +3 Query: 198 GVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFATGIGNTDAGFVMGTGKALLKVPPT 377 G+ H+ + G PG ++ DSHT GA G A GIG ++ V+ + L P T Sbjct: 105 GIIHVVGPERGLTLPGMTIVCGDSHTSTHGAMGAVAFGIGTSEVEMVLASQCILQSRPKT 164 Query: 378 IRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIE 557 +R +DG++ + AKD+ L ++ +++ SGAT +E+ G I SLTME R+TLCN+ IE Sbjct: 165 MRITVDGKLGKGVTAKDIALYMMSKMTTSGATGYFVEYAGEAIRSLTMEGRLTLCNLSIE 224 Query: 558 AGGKNGVVPADETTFKY 608 G + G++ DE TF+Y Sbjct: 225 MGARGGMIAPDEVTFEY 241
>LEU2_BACFN (Q5LAB1) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 464 Score = 107 bits (266), Expect = 4e-23 Identities = 53/137 (38%), Positives = 81/137 (59%) Frame = +3 Query: 198 GVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFATGIGNTDAGFVMGTGKALLKVPPT 377 G+ H+ + G PG ++ DSHT GA G A GIG ++ V+ + L P T Sbjct: 105 GIIHVVGPERGLTLPGMTIVCGDSHTSTHGAMGAVAFGIGTSEVEMVLASQCILQSRPKT 164 Query: 378 IRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIE 557 +R +DG++ + AKD+ L ++ +++ SGAT +E+ G I SLTME R+TLCN+ IE Sbjct: 165 MRITVDGKLGKGVTAKDIALYMMSKMTTSGATGYFVEYAGEAIRSLTMEGRLTLCNLSIE 224 Query: 558 AGGKNGVVPADETTFKY 608 G + G++ DE TF+Y Sbjct: 225 MGARGGMIAPDEVTFEY 241
>LEU2_BACC1 (Q73B98) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 464 Score = 107 bits (266), Expect = 4e-23 Identities = 54/138 (39%), Positives = 80/138 (57%) Frame = +3 Query: 195 KGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFATGIGNTDAGFVMGTGKALLKVPP 374 +G+ H+ + G +PG+ ++ DSHT GAFG A GIG ++ V+ T + P Sbjct: 104 QGIVHVIGPELGLTQPGKTIVCGDSHTATHGAFGALAFGIGTSEVEHVLATQTLWQRKPK 163 Query: 375 TIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVI 554 + L G++ + AKD+IL ++ + V+ T MEF G TI+++ MEERMTLCNM I Sbjct: 164 AMGIELKGKLQKGVYAKDIILHLLSKYGVAVGTGYVMEFYGETIQAMEMEERMTLCNMAI 223 Query: 555 EAGGKNGVVPADETTFKY 608 E G K G++ DE T Y Sbjct: 224 EGGAKAGIIAPDEKTVAY 241
>LEU2_SILPO (Q5LX06) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 468 Score = 106 bits (265), Expect = 5e-23 Identities = 54/155 (34%), Positives = 85/155 (54%) Frame = +3 Query: 144 YFYDIKDLSDFRANPDYKGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFATGIGNT 323 ++Y + D+ +G+ HI ++G PG ++ DSHT GAFG A GIG + Sbjct: 99 HYYPVDDIR--------QGIVHIVGPEQGWTLPGMTVVCGDSHTATHGAFGALAHGIGTS 150 Query: 324 DAGFVMGTGKALLKVPPTIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSMEFVGST 503 + V+ T + K ++ + G++ P + AKD+ L +IG +G T +E+ G Sbjct: 151 EVEHVLATQTLIQKKSKNMKVEITGKLNPGVTAKDITLAVIGATGTAGGTGYVIEYCGEA 210 Query: 504 IESLTMEERMTLCNMVIEAGGKNGVVPADETTFKY 608 I L+ME RMT+CNM IE G + G++ D+TTF Y Sbjct: 211 IRDLSMEGRMTVCNMAIEGGARAGLIAPDQTTFDY 245
>LEU2_BACSU (P80858) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) (Superoxide-inducible protein 10) (SOI10) Length = 472 Score = 106 bits (265), Expect = 5e-23 Identities = 53/138 (38%), Positives = 81/138 (58%) Frame = +3 Query: 195 KGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFATGIGNTDAGFVMGTGKALLKVPP 374 +G+ H+ + G PG+ ++ DSHT GAFG A GIG ++ V+ T + P Sbjct: 105 QGIVHVVGPELGLTLPGKTIVCGDSHTSTHGAFGALAFGIGTSEVEHVLSTQTLWQQRPK 164 Query: 375 TIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVI 554 T+ +DG + + AKD+IL +IG+ V T +E+ G ++TM+ERMT+CNM I Sbjct: 165 TLEVRVDGTLQKGVTAKDVILAVIGKYGVKFGTGYVIEYTGEVFRNMTMDERMTVCNMSI 224 Query: 555 EAGGKNGVVPADETTFKY 608 EAG + G++ DE TF+Y Sbjct: 225 EAGARAGLIAPDEVTFEY 242
>LEU2_BACLD (Q65GJ0) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 472 Score = 106 bits (265), Expect = 5e-23 Identities = 53/138 (38%), Positives = 82/138 (59%) Frame = +3 Query: 195 KGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFATGIGNTDAGFVMGTGKALLKVPP 374 +G+ H+ + G PG+ ++ DSHT GAFG A GIG ++ V+ T + P Sbjct: 105 QGIVHVIGPELGLTLPGKTIVCGDSHTSTHGAFGALAFGIGTSEVEHVLSTQTLWQQKPK 164 Query: 375 TIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVI 554 T+ +DG++ + AKD+IL IIG+ V +E+ G +++M+ERMT+CNM I Sbjct: 165 TLEIRVDGKLQKGVTAKDVILAIIGKYGVKFGAGYVIEYTGEVFRNMSMDERMTVCNMSI 224 Query: 555 EAGGKNGVVPADETTFKY 608 EAG + G++ DETTF+Y Sbjct: 225 EAGARAGLIAPDETTFEY 242
>LEU2_CORGL (P58946) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 481 Score = 106 bits (265), Expect = 5e-23 Identities = 56/138 (40%), Positives = 79/138 (57%) Frame = +3 Query: 195 KGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFATGIGNTDAGFVMGTGKALLKVPP 374 +G+ H Q G +PG ++ DSHT GAFG A GIG ++ VM T LK Sbjct: 121 QGIVHTVGPQLGATQPGMTIVCGDSHTSTHGAFGSMAFGIGTSEVEHVMATQTLPLKPFK 180 Query: 375 TIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVI 554 T+ + GE+ P + +KDLIL II +I G +E+ G I ++M+ RMT+CNM I Sbjct: 181 TMAIEVTGELQPGVSSKDLILAIIAKIGTGGGQGYVLEYRGEAIRKMSMDARMTMCNMSI 240 Query: 555 EAGGKNGVVPADETTFKY 608 EAG + G++ D+TTF Y Sbjct: 241 EAGARAGMIAPDQTTFDY 258
>LEU21_MANSM (Q65VS0) 3-isopropylmalate dehydratase large subunit 1 (EC| 4.2.1.33) (Isopropylmalate isomerase 1) (Alpha-IPM isomerase 1) (IPMI 1) Length = 475 Score = 106 bits (265), Expect = 5e-23 Identities = 54/161 (33%), Positives = 87/161 (54%), Gaps = 3/161 (1%) Frame = +3 Query: 135 KIKYFYDIKDLSD---FRANPDYKGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFA 305 ++ YF + L D F +G+ H+ ++G PG V+ DSHT GAFG F Sbjct: 88 QVNYFRENSKLFDIELFDVTDPRQGIEHVVAHEQGLALPGMVIAAGDSHTTTYGAFGAFG 147 Query: 306 TGIGNTDAGFVMGTGKALLKVPPTIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSM 485 GIG ++ ++ T + K +R L G++P AKD+I+ ++ +I GAT ++ Sbjct: 148 FGIGTSEIEHLLATQTLVYKKLKNMRVTLTGKLPFGTTAKDVIMALVAKIGADGATNYAI 207 Query: 486 EFVGSTIESLTMEERMTLCNMVIEAGGKNGVVPADETTFKY 608 EF G I+ L++E RMT+CNM +E G + + DE ++Y Sbjct: 208 EFCGEVIDELSVEGRMTICNMAVECGARGAFMAPDEKVYEY 248
>LEU2_THEFY (Q47SA3) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 465 Score = 106 bits (265), Expect = 5e-23 Identities = 55/138 (39%), Positives = 80/138 (57%) Frame = +3 Query: 195 KGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFATGIGNTDAGFVMGTGKALLKVPP 374 +G+ H+ Q G +PG ++ DSHT GAFG A GIG + VM T + Sbjct: 105 QGIVHVIGPQLGLTQPGMTIVCGDSHTSTHGAFGALAFGIGTSQVEHVMATQTLPMTPFK 164 Query: 375 TIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVI 554 T+ ++G++ P + AKD+IL +I +I G +E+ G I SL+ME RMT+CNM I Sbjct: 165 TMAVNVEGKLKPGVTAKDIILAVIAQIGTGGGQGHVIEYRGEAIRSLSMEARMTICNMSI 224 Query: 555 EAGGKNGVVPADETTFKY 608 EAG + G++ D+TTF Y Sbjct: 225 EAGARAGMIAPDQTTFDY 242
>LEU2_SYNP6 (Q5MZY3) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 468 Score = 106 bits (264), Expect = 6e-23 Identities = 60/162 (37%), Positives = 89/162 (54%) Frame = +3 Query: 123 CQEQKIKYFYDIKDLSDFRANPDYKGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQF 302 C+E I+ FY+I S +G+ H+ ++G +PG + DSHT GAFG Sbjct: 91 CRENGIR-FYNIGSGS--------QGIVHVIAPEQGLTQPGMTIACGDSHTSTHGAFGAI 141 Query: 303 ATGIGNTDAGFVMGTGKALLKVPPTIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRS 482 A GIG + V+ + L + ++GE+ P + AKD+IL II ++ V G + Sbjct: 142 AFGIGTSQVRDVLASQTLALSKLKVRKIEVNGELQPGVYAKDVILHIIRKLGVKGGVGYA 201 Query: 483 MEFVGSTIESLTMEERMTLCNMVIEAGGKNGVVPADETTFKY 608 EF GST +++MEERMT+CNM IE G + G V D+ T+ Y Sbjct: 202 YEFAGSTFAAMSMEERMTVCNMAIEGGARCGYVNPDQITYDY 243
>LEU2_RHINI (P55811) 3-isopropylmalate dehydratase (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 750 Score = 106 bits (264), Expect = 6e-23 Identities = 55/148 (37%), Positives = 84/148 (56%) Frame = +3 Query: 165 LSDFRANPDYKGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFATGIGNTDAGFVMG 344 L+ F +G+ H+ ++G PG ++ DSHT GAFG A GIG ++ V+ Sbjct: 101 LTYFGMEDSRQGIVHVIGPEQGFTLPGTTVVCGDSHTSTHGAFGALAFGIGTSEVEHVLA 160 Query: 345 TGKALLKVPPTIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTME 524 T L K +R ++G+ + +KD+ L +IG I +G T +EF G ESL+ME Sbjct: 161 TQTLLQKKSKNMRIRVEGKPSAGVTSKDIALHVIGVIGTAGGTGCVIEFCGEANESLSME 220 Query: 525 ERMTLCNMVIEAGGKNGVVPADETTFKY 608 RM++CNM IEAG + G++ D+ TF+Y Sbjct: 221 SRMSICNMSIEAGARAGMIAPDDITFEY 248
>LEU2_CHRVO (Q7NUB6) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 471 Score = 106 bits (264), Expect = 6e-23 Identities = 55/138 (39%), Positives = 80/138 (57%) Frame = +3 Query: 195 KGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFATGIGNTDAGFVMGTGKALLKVPP 374 +G+ H+ ++G PG ++ DSHT GAFG A GIG ++ VM T + K Sbjct: 107 QGIVHVMGPEQGATLPGMTVVCGDSHTSTHGAFGALAHGIGTSEVEHVMATQCLVAKKSK 166 Query: 375 TIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVI 554 + +DG + + AKD+ L IIG+I +G T ++EF G I L+ME RMTLCNM I Sbjct: 167 NMLVRVDGRLGAGITAKDVALAIIGKIGTAGGTGYAIEFGGEAIRGLSMEGRMTLCNMAI 226 Query: 555 EAGGKNGVVPADETTFKY 608 E G ++G+V D+ T +Y Sbjct: 227 EGGARSGMVAVDDKTIEY 244
>LEU2_BUCRP (P48573) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 471 Score = 106 bits (264), Expect = 6e-23 Identities = 54/149 (36%), Positives = 87/149 (58%) Frame = +3 Query: 162 DLSDFRANPDYKGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFATGIGNTDAGFVM 341 ++S + N +G+ H+ ++G PG ++ DSHT GAFG + GIG ++ V+ Sbjct: 94 NISLYDLNNPKQGIVHVIGPEQGMTLPGMTIVCGDSHTSTHGAFGALSFGIGTSEVEHVL 153 Query: 342 GTGKALLKVPPTIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTM 521 T + ++ + G++ ++ AKD+IL IIG++ SG + +EF G I+ + M Sbjct: 154 VTQTLKQQRLKNMKIQIKGKIKNFVTAKDIILFIIGKLGTSGGSGYVIEFCGDVIKKMNM 213 Query: 522 EERMTLCNMVIEAGGKNGVVPADETTFKY 608 EERMT+CNM IE G K+ ++ DETTF Y Sbjct: 214 EERMTVCNMAIEMGAKSALIAPDETTFLY 242
>LEU21_DEIRA (Q9RTY9) 3-isopropylmalate dehydratase large subunit 1 (EC| 4.2.1.33) (Isopropylmalate isomerase 1) (Alpha-IPM isomerase 1) (IPMI 1) Length = 434 Score = 106 bits (264), Expect = 6e-23 Identities = 55/139 (39%), Positives = 82/139 (58%), Gaps = 1/139 (0%) Frame = +3 Query: 195 KGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFATGIGNTDAGFVMGTGKALLKVPP 374 +G+CH L +E +PG ++LG+DSH+ GA F +G+G TD +GK L+VP Sbjct: 113 RGICHQVLMEEKLAQPGWIVLGSDSHSTTYGAVAAFGSGMGATDIALAAASGKTWLRVPE 172 Query: 375 TIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVI 554 +++ L G++ P + AKD+ L++I + GATY+S+E + T ERMTL N+ + Sbjct: 173 SVKVTLTGDLRPGVTAKDVALEMIRVLGADGATYQSVEIHAG--DRFTRGERMTLANLCV 230 Query: 555 EAGGKNG-VVPADETTFKY 608 EAG K G VVP E Y Sbjct: 231 EAGAKAGLVVPGGEILTDY 249
>LEU2_HAEI8 (Q4QLS2) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 469 Score = 106 bits (264), Expect = 6e-23 Identities = 54/138 (39%), Positives = 81/138 (58%) Frame = +3 Query: 195 KGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFATGIGNTDAGFVMGTGKALLKVPP 374 +G+ H+ ++G PG ++ DSHT GAFG A GIG ++ V+ T Sbjct: 105 QGIVHVMGPEQGLTLPGMTIVCGDSHTATHGAFGALAFGIGTSEVEHVLATQTLKQARAK 164 Query: 375 TIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVI 554 +++ + G++ + AKD+IL IIG+ +++G T +EF G I L+ME RMT+CNM I Sbjct: 165 SMKIEVRGKVASGITAKDIILAIIGKTTMAGGTGHVVEFCGEAIRDLSMEGRMTVCNMAI 224 Query: 555 EAGGKNGVVPADETTFKY 608 E G K G++ DETTF Y Sbjct: 225 EMGAKAGLIAPDETTFAY 242
>LEU2_PASMU (Q9CJN7) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 467 Score = 105 bits (263), Expect = 8e-23 Identities = 53/138 (38%), Positives = 80/138 (57%) Frame = +3 Query: 195 KGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFATGIGNTDAGFVMGTGKALLKVPP 374 +G+ H+ ++G PG ++ DSHT GAFG A GIG ++ V+ T Sbjct: 104 QGIVHVMGPEQGLTLPGMTIVCGDSHTATHGAFGALAFGIGTSEVEHVLATQTIKQARAK 163 Query: 375 TIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVI 554 ++ + G++ + AKD++L IIG+ ++ G T +EF G I L+ME RMT+CNM I Sbjct: 164 KMKIEVRGKVRDGISAKDIVLAIIGKTTMGGGTGHVVEFCGEAIRDLSMEGRMTVCNMAI 223 Query: 555 EAGGKNGVVPADETTFKY 608 E G K+G++ DETTF Y Sbjct: 224 ELGAKSGIIAPDETTFAY 241
>LEU2_PROMT (Q46HB8) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 469 Score = 105 bits (262), Expect = 1e-22 Identities = 57/138 (41%), Positives = 76/138 (55%) Frame = +3 Query: 195 KGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFATGIGNTDAGFVMGTGKALLKVPP 374 +GV H+ + G +PG + DSHT GAFG A GIG + V+ + + Sbjct: 106 QGVVHVMAPELGLTQPGMTVACGDSHTSTHGAFGAIAFGIGTSQVRDVLASQSLAMNKLK 165 Query: 375 TIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVI 554 R ++GE+ + AKDLIL II + V G + EF G IE L+ME RMT+CNM I Sbjct: 166 VRRIWVEGELQKGVYAKDLILHIIRHLGVKGGVGFAYEFAGPAIEKLSMEGRMTICNMAI 225 Query: 555 EAGGKNGVVPADETTFKY 608 E G + G + DETTFKY Sbjct: 226 EGGARCGYINPDETTFKY 243
>LEU2_AZOSE (Q5P1J8) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 469 Score = 105 bits (262), Expect = 1e-22 Identities = 57/138 (41%), Positives = 81/138 (58%) Frame = +3 Query: 195 KGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFATGIGNTDAGFVMGTGKALLKVPP 374 +G+ H+ + G PG ++ DSHT GAF A GIG ++ V+ T L K Sbjct: 107 QGIVHVIGPEIGATLPGMTVVCGDSHTSTHGAFACLAHGIGTSEVEHVLATQCLLQKRSK 166 Query: 375 TIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVI 554 T+ +DGE+ + AKD+ L IIG + +G T ++EF GS I +L+ME RMT+CNM I Sbjct: 167 TMLVRVDGELGRGVSAKDIALAIIGRLGTAGGTGYAIEFGGSAIRALSMEGRMTICNMAI 226 Query: 555 EAGGKNGVVPADETTFKY 608 EAG + G+V D+TT Y Sbjct: 227 EAGARAGLVAVDQTTIDY 244
>LEU2_GLOVI (Q7NFV7) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 473 Score = 103 bits (258), Expect = 3e-22 Identities = 52/138 (37%), Positives = 76/138 (55%) Frame = +3 Query: 195 KGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFATGIGNTDAGFVMGTGKALLKVPP 374 +G+ H+ ++G +PG + DSHT GAFG A GIG + V+ T L Sbjct: 108 QGIVHVIAPEQGFTQPGMTIACGDSHTATHGAFGAIAFGIGTSQVRDVLATQTLALDKLK 167 Query: 375 TIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVI 554 R ++G + P + AKD+IL II ++ V + EF G+T E++ MEERMT+CNM I Sbjct: 168 VRRIEMNGSLHPGVFAKDVILHIIRKLGVKAGVGYAYEFAGTTFEAMNMEERMTVCNMAI 227 Query: 555 EAGGKNGVVPADETTFKY 608 E G + G + D T+ Y Sbjct: 228 EGGARCGYINPDAVTYAY 245
>LEU2_PROMA (Q7VDT0) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 468 Score = 103 bits (258), Expect = 3e-22 Identities = 54/145 (37%), Positives = 77/145 (53%) Frame = +3 Query: 174 FRANPDYKGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFATGIGNTDAGFVMGTGK 353 F+ +G+ H+ + G +PG + DSHT GAFG A GIG + V+ + Sbjct: 99 FKIGSGNQGIVHVIAPETGLTQPGMTIACGDSHTSTHGAFGSIAFGIGTSQVRDVLASQT 158 Query: 354 ALLKVPPTIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERM 533 +K R DG + + AKDLIL +I ++ V + EF G I+ L+MEERM Sbjct: 159 LAMKKLKVKRIWFDGYLQKGVFAKDLILHVIQKLGVKDGVGYAYEFAGPAIDGLSMEERM 218 Query: 534 TLCNMVIEAGGKNGVVPADETTFKY 608 T+CNM IE G + G + D+TTF Y Sbjct: 219 TICNMAIEGGARCGYINPDKTTFNY 243
>LEU2_DECAR (Q47HR4) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 468 Score = 103 bits (258), Expect = 3e-22 Identities = 58/152 (38%), Positives = 82/152 (53%) Frame = +3 Query: 153 DIKDLSDFRANPDYKGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFATGIGNTDAG 332 ++ L+ F G+ H+ + G PG ++ DSHT GAF A GIG ++ Sbjct: 92 EVGALAYFPFKDQRMGILHVVGPENGATLPGMTVVCGDSHTSTHGAFACMAHGIGTSEVE 151 Query: 333 FVMGTGKALLKVPPTIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIES 512 V+ T L K T+ ++G++ + AKD+ L IIG I +G T ++EF GS I Sbjct: 152 HVLATQCLLQKRSKTMLVAVEGKLGKGVTAKDVALAIIGTIGTAGGTGYAIEFGGSAIRG 211 Query: 513 LTMEERMTLCNMVIEAGGKNGVVPADETTFKY 608 L+ME RMTLCNM IE G + G V D+TT Y Sbjct: 212 LSMEGRMTLCNMAIEGGARLGFVAVDDTTINY 243
>LEU2_SYNEL (Q8DKF0) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 469 Score = 103 bits (257), Expect = 4e-22 Identities = 54/138 (39%), Positives = 76/138 (55%) Frame = +3 Query: 195 KGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFATGIGNTDAGFVMGTGKALLKVPP 374 +G+ H+ ++G +PG + DSHT GAFG A GIG + V+ T L Sbjct: 108 QGIVHVIAPEQGLTQPGMTIACGDSHTSTHGAFGAIAFGIGTSQVRDVLATQTLALNKLK 167 Query: 375 TIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVI 554 + ++G + + AKD+IL +I + V G + EF G+T L+MEERMT+CNM I Sbjct: 168 VRKVEVNGSLAAGVYAKDVILHVIRHLGVKGGVGYAYEFAGTTFGQLSMEERMTVCNMAI 227 Query: 555 EAGGKNGVVPADETTFKY 608 E G + G V DETTF Y Sbjct: 228 EGGARCGYVNPDETTFAY 245
>LEU2_THET8 (Q9ZND5) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 472 Score = 103 bits (256), Expect = 5e-22 Identities = 56/138 (40%), Positives = 77/138 (55%) Frame = +3 Query: 195 KGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFATGIGNTDAGFVMGTGKALLKVPP 374 +G+ H+ Q G +PG + DSHT GAFG A GIG + V+ T + Sbjct: 105 QGIVHVIGPQLGLTQPGMTIACGDSHTSTHGAFGAVAFGIGTSQVRDVLATQTLAAQKLK 164 Query: 375 TIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVI 554 R ++G + P + AKD+IL II + V G + E+ GS +E++ ME RMTLCNM I Sbjct: 165 VRRINVEGRLAPGVYAKDVILHIIRHLGVKGGLGYAYEYGGSAVEAMDMESRMTLCNMSI 224 Query: 555 EAGGKNGVVPADETTFKY 608 E G + G V DETTF+Y Sbjct: 225 EGGARIGYVNPDETTFQY 242
>LEU2_THET2 (Q72JB3) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 472 Score = 103 bits (256), Expect = 5e-22 Identities = 56/138 (40%), Positives = 77/138 (55%) Frame = +3 Query: 195 KGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFATGIGNTDAGFVMGTGKALLKVPP 374 +G+ H+ Q G +PG + DSHT GAFG A GIG + V+ T + Sbjct: 105 QGIVHVIGPQLGLTQPGMTIACGDSHTSTHGAFGAVAFGIGTSQVRDVLATQTLAAQKLK 164 Query: 375 TIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVI 554 R ++G + P + AKD+IL II + V G + E+ GS +E++ ME RMTLCNM I Sbjct: 165 VRRINVEGRLAPGVYAKDVILHIIRHLGVKGGLGYAYEYGGSAVEAMDMESRMTLCNMSI 224 Query: 555 EAGGKNGVVPADETTFKY 608 E G + G V DETTF+Y Sbjct: 225 EGGARIGYVNPDETTFQY 242
>LEU2_SYNY3 (P54384) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 468 Score = 102 bits (255), Expect = 7e-22 Identities = 52/138 (37%), Positives = 77/138 (55%) Frame = +3 Query: 195 KGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFATGIGNTDAGFVMGTGKALLKVPP 374 +G+ H+ ++G +PG + DSHT GAFG A GIG + V+ L Sbjct: 106 QGIVHVIAPEQGLTQPGMTIACGDSHTSTHGAFGAIAFGIGTSQVRDVLAAQSLSLNKLK 165 Query: 375 TIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVI 554 + ++G++ P + AKD+IL II ++ V G + E+ GST ++ MEERMT+CNM I Sbjct: 166 VRKIEVNGDLAPGVYAKDVILHIIRKLGVKGGVGYAYEYAGSTFVAMNMEERMTVCNMSI 225 Query: 555 EAGGKNGVVPADETTFKY 608 E G + G + DE TF Y Sbjct: 226 EGGARCGYINPDEVTFAY 243
>LEU2_ACTTI (Q44427) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 485 Score = 102 bits (254), Expect = 9e-22 Identities = 55/138 (39%), Positives = 76/138 (55%) Frame = +3 Query: 195 KGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFATGIGNTDAGFVMGTGKALLKVPP 374 +G+ H+ Q G +PG ++ DSHT GA G A GIG ++ V+ T P Sbjct: 125 QGIVHVIGPQLGLTQPGMTIVCGDSHTATHGASGALAFGIGTSEVEHVLATQTLPQSKPK 184 Query: 375 TIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVI 554 T+ + GE+ P + AKDLIL +I + G +E+ G I L+ME RMT+CNM I Sbjct: 185 TMAVTVVGELRPGVSAKDLILTLITQTGTGGGNGHIVEYRGEAIRKLSMEGRMTICNMSI 244 Query: 555 EAGGKNGVVPADETTFKY 608 E G K G++ DETTF Y Sbjct: 245 EWGAKAGMIAPDETTFDY 262
>LEU2_ACIAD (Q6FEW0) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 477 Score = 102 bits (254), Expect = 9e-22 Identities = 52/149 (34%), Positives = 85/149 (57%) Frame = +3 Query: 162 DLSDFRANPDYKGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFATGIGNTDAGFVM 341 ++ +F N +G+ H+ ++G PG ++ DSHT GAFG A GIG ++ V+ Sbjct: 105 NIVEFGINDIRQGIVHVVGPEQGLTLPGMTVVCGDSHTATHGAFGCLAHGIGTSEVEHVL 164 Query: 342 GTGKALLKVPPTIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTM 521 T + K + +DG++ + KD++L IIG+I +G T ++EF G +++ Sbjct: 165 ATQCLIQKKSKNMLIRVDGQLGKGVTPKDVVLAIIGKIGTAGGTGYAIEFGGQVFRDMSI 224 Query: 522 EERMTLCNMVIEAGGKNGVVPADETTFKY 608 E RMT+CNM IEAG + G+V D+ T +Y Sbjct: 225 EGRMTVCNMAIEAGARVGMVAVDDKTIEY 253
>LEU2_BUCAP (O85065) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 469 Score = 102 bits (254), Expect = 9e-22 Identities = 56/163 (34%), Positives = 90/163 (55%), Gaps = 5/163 (3%) Frame = +3 Query: 135 KIKYFYDIKDLSDFRA-----NPDYKGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQ 299 KI+ IK+ +F N +G+ H+ ++G PG ++ DSHT GAFG Sbjct: 80 KIQMQQLIKNCEEFNIALYDLNNPKQGIVHVIGPEQGLTLPGSTIVCGDSHTSTHGAFGA 139 Query: 300 FATGIGNTDAGFVMGTGKALLKVPPTIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYR 479 + GIG ++ V+ T + ++ + G++ ++ AKD+IL IIG++ S + Sbjct: 140 LSFGIGTSEVEHVLVTQTLKQQRFKNMKIKIVGKVKKFITAKDIILFIIGKLGTSSGSGY 199 Query: 480 SMEFVGSTIESLTMEERMTLCNMVIEAGGKNGVVPADETTFKY 608 +EF G I+ + MEERMT+CNM IE G K+ ++ DETT+ Y Sbjct: 200 VIEFCGDVIKKMNMEERMTICNMAIEMGAKSALIAPDETTYLY 242
>LEU2_ANASP (Q8YX02) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 467 Score = 100 bits (250), Expect = 3e-21 Identities = 58/162 (35%), Positives = 84/162 (51%) Frame = +3 Query: 123 CQEQKIKYFYDIKDLSDFRANPDYKGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQF 302 CQE I FY+I +G+ H+ + G +PG + DSHT + GAFG Sbjct: 91 CQENNIT-FYNI--------GSGNQGIVHVIAPELGLTQPGMTIACGDSHTSSHGAFGAI 141 Query: 303 ATGIGNTDAGFVMGTGKALLKVPPTIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRS 482 A GIG + V+ + L + ++G + P + AKD+IL II + V G + Sbjct: 142 AFGIGTSQVRDVLASQTLSLSKLKVRKIEVNGALNPGVYAKDVILHIIRTLGVKGGVGYA 201 Query: 483 MEFVGSTIESLTMEERMTLCNMVIEAGGKNGVVPADETTFKY 608 E+ G+T E + MEERMT+CNM IE G + G V D+ T+ Y Sbjct: 202 YEYAGTTFEQMNMEERMTVCNMAIEGGARCGYVNPDQVTYDY 243
>LEU2_CAMJR (Q5HS78) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 468 Score = 100 bits (249), Expect = 3e-21 Identities = 55/138 (39%), Positives = 75/138 (54%) Frame = +3 Query: 195 KGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFATGIGNTDAGFVMGTGKALLKVPP 374 +G+ HI + G PG L+ DSHT GAFG A GIG ++ VM T Sbjct: 105 QGIVHIVGPELGFTLPGVTLVCGDSHTATHGAFGALAFGIGTSEVEHVMATQTLKQAKLK 164 Query: 375 TIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVI 554 T++ G+ + KDLIL +I + + T ++EF G I +L+ME RMTLCNM I Sbjct: 165 TMKIECKGQFQKGVYTKDLILYLIAQYGTAKGTGYAIEFCGELIRNLSMEARMTLCNMAI 224 Query: 555 EAGGKNGVVPADETTFKY 608 E G K G++ DE TF+Y Sbjct: 225 EFGAKVGMIAPDEITFEY 242
>LEU2_SYNPX (Q7U9J4) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 472 Score = 100 bits (249), Expect = 3e-21 Identities = 53/138 (38%), Positives = 75/138 (54%) Frame = +3 Query: 195 KGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFATGIGNTDAGFVMGTGKALLKVPP 374 +G+ H+ + G +PG + DSHT GAFG A GIG + V+ + + Sbjct: 106 QGIVHVIAPELGLTQPGMTVACGDSHTSTHGAFGAIAFGIGTSQVRDVLASQSLAMSKLK 165 Query: 375 TIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVI 554 R ++G + + AKDLIL +I + V G + EF G +E+L+MEERMTLCNM I Sbjct: 166 VRRIQVNGRLSDGVSAKDLILHVIRTLGVKGGVGFAYEFAGPAVEALSMEERMTLCNMAI 225 Query: 555 EAGGKNGVVPADETTFKY 608 E G + G V D+ TF Y Sbjct: 226 EGGARCGYVNPDQVTFDY 243
>LEU2_BUCBP (P59519) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 471 Score = 100 bits (249), Expect = 3e-21 Identities = 52/145 (35%), Positives = 80/145 (55%) Frame = +3 Query: 174 FRANPDYKGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFATGIGNTDAGFVMGTGK 353 F N ++G+ H+ ++G PG ++ DSHT GAFG A GIG ++ V+ T Sbjct: 98 FDLNHPHQGIVHVIGPEQGITLPGMTIVCGDSHTSTHGAFGALAFGIGTSEVEHVLATQT 157 Query: 354 ALLKVPPTIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERM 533 ++ ++G++ + AKD+IL +I ++ VS +EF G + L+ME RM Sbjct: 158 LKQNRLKSMHIKINGDIDIGITAKDIILFVIKQLGVSRGLGYVIEFSGEIVSKLSMESRM 217 Query: 534 TLCNMVIEAGGKNGVVPADETTFKY 608 TLCNM IE G K+G++ D TF Y Sbjct: 218 TLCNMSIEMGAKSGIIAPDSVTFSY 242
>LEU2_CAMJE (Q9PLW1) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 470 Score = 100 bits (249), Expect = 3e-21 Identities = 55/138 (39%), Positives = 75/138 (54%) Frame = +3 Query: 195 KGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFATGIGNTDAGFVMGTGKALLKVPP 374 +G+ HI + G PG L+ DSHT GAFG A GIG ++ VM T Sbjct: 107 QGIVHIVGPELGFTLPGVTLVCGDSHTATHGAFGALAFGIGTSEVEHVMATQTLKQAKLK 166 Query: 375 TIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVI 554 T++ G+ + KDLIL +I + + T ++EF G I +L+ME RMTLCNM I Sbjct: 167 TMKIECKGQFQKGVYTKDLILYLIAQYGTAKGTGYAIEFCGELIRNLSMEARMTLCNMAI 226 Query: 555 EAGGKNGVVPADETTFKY 608 E G K G++ DE TF+Y Sbjct: 227 EFGAKVGMIAPDEITFEY 244
>LEU2_HALMA (Q5V518) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 473 Score = 99.8 bits (247), Expect = 6e-21 Identities = 51/138 (36%), Positives = 79/138 (57%) Frame = +3 Query: 195 KGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFATGIGNTDAGFVMGTGKALLKVPP 374 +G+ H+ ++G +PG+ ++ DSHT GAFG A GIG + V+ T ++ Sbjct: 106 QGIVHVIGPEQGITQPGKTIVCGDSHTSTHGAFGALAFGIGTSQIRDVLATQTIAMEKQK 165 Query: 375 TIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVI 554 + + GE+ + AKD+IL+II + G E+ G TIE+L ME RM++CNM I Sbjct: 166 VRKIEVTGELDEGVEAKDIILEIIRRLGTEGGVGYVYEYAGETIENLDMEGRMSICNMSI 225 Query: 555 EAGGKNGVVPADETTFKY 608 E G + G V DETT+++ Sbjct: 226 EGGARAGYVNPDETTYEW 243
>LEU2_HALVO (Q7ZAG7) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 473 Score = 98.6 bits (244), Expect = 1e-20 Identities = 51/138 (36%), Positives = 77/138 (55%) Frame = +3 Query: 195 KGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFATGIGNTDAGFVMGTGKALLKVPP 374 +G+ H+ ++G +PG ++ DSHT GAFG A GIG + V+ T ++ Sbjct: 106 QGIVHVIGPEKGLTQPGMTIVCGDSHTSTHGAFGALAFGIGTSQIRDVLATQTVAMEKKK 165 Query: 375 TIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVI 554 + + GE+ P + AKD+IL+II + G E+ G IE L ME RM++CNM I Sbjct: 166 VRKIEVTGELGPGVEAKDVILEIIRRLGTEGGVGYVYEYAGEAIEDLDMEGRMSICNMSI 225 Query: 555 EAGGKNGVVPADETTFKY 608 E G + G V DETT+++ Sbjct: 226 EGGARAGYVNPDETTYEW 243
>LEU2_PROMP (Q7V336) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 469 Score = 98.2 bits (243), Expect = 2e-20 Identities = 55/162 (33%), Positives = 79/162 (48%) Frame = +3 Query: 123 CQEQKIKYFYDIKDLSDFRANPDYKGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQF 302 C E KIK+F +G+ H+ + G +PG + DSHT GAFG Sbjct: 91 CIEHKIKFF---------NIGSGNQGIVHVVAPELGLTQPGMTIACGDSHTSTHGAFGSI 141 Query: 303 ATGIGNTDAGFVMGTGKALLKVPPTIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRS 482 A GIG + V+ + + + + ++ + AKDL+L II ++ V + Sbjct: 142 AFGIGTSQVRDVLASQTIAMNKLKVRQIWCENKLSNGIYAKDLVLHIINQLGVKAGVGYA 201 Query: 483 MEFVGSTIESLTMEERMTLCNMVIEAGGKNGVVPADETTFKY 608 EF G I L+MEERMT+CNM IE G + G + DE TF Y Sbjct: 202 YEFAGPAISELSMEERMTICNMSIEGGARCGYINPDEKTFSY 243
>LEU2_STRGN (Q9AIM3) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) (Fragment) Length = 456 Score = 98.2 bits (243), Expect = 2e-20 Identities = 51/140 (36%), Positives = 74/140 (52%) Frame = +3 Query: 189 DYKGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFATGIGNTDAGFVMGTGKALLKV 368 + +G+ H+ + G +PG+ ++ DSHT GAFG A GIG ++ V T Sbjct: 99 ELQGIVHMVGPETGKTQPGKFIVCGDSHTATHGAFGAIAFGIGTSEVEHVFATQTIWQVK 158 Query: 369 PPTIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNM 548 P + G P + +KD IL +I V+ +E+ G IE LTMEERMT+CNM Sbjct: 159 PKKMLVKFTGVPPKGVYSKDFILALIARYGVAAGVGHVVEYAGDAIEHLTMEERMTICNM 218 Query: 549 VIEAGGKNGVVPADETTFKY 608 IE G K G++ D+ T+ Y Sbjct: 219 SIEFGSKMGIMNPDQKTYDY 238
>LEU2_LACLA (Q02142) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 460 Score = 97.8 bits (242), Expect = 2e-20 Identities = 49/138 (35%), Positives = 74/138 (53%) Frame = +3 Query: 195 KGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFATGIGNTDAGFVMGTGKALLKVPP 374 +G+ H+ + G +PG+ ++ DSHT GAFG A GIG ++ V+ T P Sbjct: 105 QGIVHMVAPESGRTQPGKTIVCGDSHTATNGAFGAIAFGIGTSEVEHVLATQTIWQVKPK 164 Query: 375 TIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVI 554 ++ G + +KD IL +I + V ++E+ G I L+MEERMT+CNM I Sbjct: 165 RMKIEFQGHPQKGIYSKDFILALIAKYGVDAGVGYAVEYSGDAISDLSMEERMTICNMSI 224 Query: 555 EAGGKNGVVPADETTFKY 608 E G K G++ DE T+ Y Sbjct: 225 EFGAKIGLMNPDEKTYDY 242
>LEU2_PROMM (Q7V4U5) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 478 Score = 97.8 bits (242), Expect = 2e-20 Identities = 53/138 (38%), Positives = 73/138 (52%) Frame = +3 Query: 195 KGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFATGIGNTDAGFVMGTGKALLKVPP 374 +G+ H+ + G +PG + DSHT GAFG A GIG + V+ + + Sbjct: 106 QGIVHVIAPELGLTQPGMTVACGDSHTSTHGAFGAIAFGIGTSQVRDVLASQSLAMNKLK 165 Query: 375 TIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVI 554 R +DG++ + AKDLIL +I + V + EF G I+ L+MEERMTLCNM I Sbjct: 166 VRRIWVDGQLGSGVYAKDLILHVIRSLGVKAGVGYAYEFAGPAIDVLSMEERMTLCNMAI 225 Query: 555 EAGGKNGVVPADETTFKY 608 E G + G V D TF Y Sbjct: 226 EGGARCGYVNPDGVTFDY 243
>LEU2_STRT1 (Q5LZF4) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 460 Score = 96.7 bits (239), Expect = 5e-20 Identities = 51/140 (36%), Positives = 76/140 (54%) Frame = +3 Query: 189 DYKGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFATGIGNTDAGFVMGTGKALLKV 368 D +G+ H+ + G +PG+ ++ DSHT GAFG A GIG ++ V T Sbjct: 103 DKQGIVHMVGPETGRTQPGKFIVCGDSHTATHGAFGAIAFGIGTSEVEHVFATQTLWQVK 162 Query: 369 PPTIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNM 548 P + G+ + +KD IL +I + V+ +E+ G I+ LTMEERMT+CNM Sbjct: 163 PKKMLLEFTGKPQKGIYSKDYILALIAKYGVACGVGYVVEYRGEAIDRLTMEERMTICNM 222 Query: 549 VIEAGGKNGVVPADETTFKY 608 IE G K G++ D+TT+ Y Sbjct: 223 SIEFGSKMGIMNPDQTTYDY 242
>LEU2_NATPD (Q3IRQ4) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 474 Score = 96.7 bits (239), Expect = 5e-20 Identities = 50/138 (36%), Positives = 77/138 (55%) Frame = +3 Query: 195 KGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFATGIGNTDAGFVMGTGKALLKVPP 374 +G+ H+ ++G +PG+ ++ DSHT GAFG A GIG + V+ T ++ Sbjct: 106 QGIVHVIGPEQGLTQPGKTIVCGDSHTSTHGAFGALAFGIGTSQIRDVLATQTIAMEKKD 165 Query: 375 TIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVI 554 + + GE+ + AKD+IL II + G E+ G IE+L ME RM++CNM I Sbjct: 166 VRKIEVTGELGEGVTAKDIILTIIRRLGTDGGVGYVYEYAGEAIENLGMEGRMSICNMSI 225 Query: 555 EAGGKNGVVPADETTFKY 608 E G + G V DETT+++ Sbjct: 226 EGGARAGYVNPDETTYEW 243
>LEU2_STRT2 (Q5M406) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 460 Score = 95.9 bits (237), Expect = 8e-20 Identities = 51/140 (36%), Positives = 75/140 (53%) Frame = +3 Query: 189 DYKGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFATGIGNTDAGFVMGTGKALLKV 368 D +G+ H+ + G +PG+ ++ DSHT GAFG A GIG ++ V T Sbjct: 103 DKQGIVHMVGPETGRTQPGKFIVCGDSHTATHGAFGTIAFGIGTSEVEHVFATQTLWQVK 162 Query: 369 PPTIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNM 548 P + G + +KD IL +I + V+ +E+ G I+ LTMEERMT+CNM Sbjct: 163 PKKMLVEFTGNPQKGIYSKDYILALIAKYGVACGVGYVVEYRGEAIDRLTMEERMTICNM 222 Query: 549 VIEAGGKNGVVPADETTFKY 608 IE G K G++ D+TT+ Y Sbjct: 223 SIEFGSKMGIMNPDQTTYDY 242
>LEU2_AZOVI (P96195) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 470 Score = 95.1 bits (235), Expect = 1e-19 Identities = 52/127 (40%), Positives = 73/127 (57%) Frame = +3 Query: 228 GHCRPGEVLLGTDSHTCNAGAFGQFATGIGNTDAGFVMGTGKALLKVPPTIRFVLDGEMP 407 G PG ++ DSHT G A GIG ++ V+ T + K ++ ++GE+P Sbjct: 119 GRHLPGMTVVCGDSHTSTHWC-GALAHGIGTSEVEHVLATQCLVAKKMKNMQVRVEGELP 177 Query: 408 PYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGVVPA 587 + AKD++L +IG I +G T ++EF GS I L+ME RMTLCNM IEAG + G+V Sbjct: 178 LGVSAKDIVLAVIGRIGTAGGTGHALEFAGSAIRGLSMEGRMTLCNMAIEAGARVGMVAV 237 Query: 588 DETTFKY 608 DE T Y Sbjct: 238 DEKTIDY 244
>LEU2_STRMU (Q8DTG4) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 461 Score = 94.4 bits (233), Expect = 2e-19 Identities = 48/138 (34%), Positives = 75/138 (54%) Frame = +3 Query: 195 KGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFATGIGNTDAGFVMGTGKALLKVPP 374 +G+ H+ + G +PG+ ++ DSHT GAFG GIG T+ V T P Sbjct: 105 QGIVHMVGPETGRTQPGKFIVCGDSHTATHGAFGAIGFGIGTTEVEHVFATQTIWQVKPK 164 Query: 375 TIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVI 554 + G+ + +KD IL +I + V+ +E++G +++L+MEERMT+CNM I Sbjct: 165 KLLVKFTGKPQKGVYSKDYILALIAKYGVALGVGYVVEYIGDAVDALSMEERMTICNMSI 224 Query: 555 EAGGKNGVVPADETTFKY 608 E G K G++ D+ TF Y Sbjct: 225 EFGSKMGIMNPDQKTFDY 242
>LEU22_PYRFU (Q8U0C0) 3-isopropylmalate dehydratase large subunit 2 (EC| 4.2.1.33) (Isopropylmalate isomerase 2) (Alpha-IPM isomerase 2) (IPMI 2) Length = 380 Score = 92.4 bits (228), Expect = 9e-19 Identities = 43/134 (32%), Positives = 76/134 (56%) Frame = +3 Query: 195 KGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFATGIGNTDAGFVMGTGKALLKVPP 374 +G+ H + + G ++++G DSHT GA G FA G+G TD ++G GK ++P Sbjct: 85 QGISHQLVVEMGLTENSKIVVGADSHTPTLGALGVFAVGMGATDVAVILGLGKTWFRIPE 144 Query: 375 TIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVI 554 ++ +L+G Y++A D+IL ++ + YR++EF +++ER+TL N V+ Sbjct: 145 SVGVILEGNPSRYVMATDVILHLLSLLKDYDMNYRAVEFFN---VPFSLDERLTLTNFVV 201 Query: 555 EAGGKNGVVPADET 596 EA K G++ + T Sbjct: 202 EANAKTGIIGEEYT 215
>ACON_YEAST (P19414) Aconitate hydratase, mitochondrial precursor (EC 4.2.1.3)| (Citrate hydro-lyase) (Aconitase) Length = 778 Score = 91.3 bits (225), Expect = 2e-18 Identities = 56/171 (32%), Positives = 88/171 (51%), Gaps = 11/171 (6%) Frame = +3 Query: 129 EQKIKYFYDI-KDLSDFRANPDYK----------GVCHIALAQEGHCRPGEVLLGTDSHT 275 E+ +K D+ K++ DF A+ K G+ H + E + PG +++GTDSHT Sbjct: 133 EKDLKRAIDLNKEVYDFLASATAKYNMGFWKPGSGIIH-QIVLENYAFPGALIIGTDSHT 191 Query: 276 CNAGAFGQFATGIGNTDAGFVMGTGKALLKVPPTIRFVLDGEMPPYLLAKDLILQIIGEI 455 NAG GQ A G+G DA VM LK P + L G+M + KD+IL++ G Sbjct: 192 PNAGGLGQLAIGVGGADAVDVMAGRPWELKAPKILGVKLTGKMNGWTSPKDIILKLAGIT 251 Query: 456 SVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGVVPADETTFKY 608 +V G T + +E+ G +++ + T+CNM E G V P +++ +Y Sbjct: 252 TVKGGTGKIVEYFGDGVDTFSATGMGTICNMGAEIGATTSVFPFNKSMIEY 302
>LEU2_MYCSM (Q938C9) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 422 Score = 90.9 bits (224), Expect = 3e-18 Identities = 54/163 (33%), Positives = 81/163 (49%) Frame = +3 Query: 120 FCQEQKIKYFYDIKDLSDFRANPDYKGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQ 299 F + I+ FYD+ G+CH +A+ G RPGE+L TDSHTC GAF Sbjct: 80 FANDYGIERFYDV----------GRHGICHQVIAENGLARPGEILACTDSHTCAGGAFNT 129 Query: 300 FATGIGNTDAGFVMGTGKALLKVPPTIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYR 479 A G+G + ++ TG+ + PTIR+ L G MP + KD+ L I + AT Sbjct: 130 AARGLGPAEVYSILCTGQTWFQASPTIRYELIGSMPAGVSGKDVFLYIAD--AFGDATNS 187 Query: 480 SMEFVGSTIESLTMEERMTLCNMVIEAGGKNGVVPADETTFKY 608 ++E+ G + S+ + +R T+ E + AD +TF Y Sbjct: 188 NLEYGGPGLASIPLNDRRTIATQGAE-------ISADFSTFAY 223
>LEU22_PYRAB (Q9V1J0) 3-isopropylmalate dehydratase large subunit 2 (EC| 4.2.1.33) (Isopropylmalate isomerase 2) (Alpha-IPM isomerase 2) (IPMI 2) Length = 380 Score = 89.7 bits (221), Expect = 6e-18 Identities = 44/129 (34%), Positives = 71/129 (55%) Frame = +3 Query: 195 KGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFATGIGNTDAGFVMGTGKALLKVPP 374 KG+ H + + G ++++G DSHT GA G FA G+G TD +G GK LKVP Sbjct: 85 KGISHQLVVELGLAEEAKIIVGGDSHTPTLGALGVFAVGMGATDVAIALGLGKIWLKVPE 144 Query: 375 TIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVI 554 +I +LDG Y++A D+++ +I + +Y ++EF + +ER+TL N + Sbjct: 145 SIAVLLDGSPREYIMASDVMIHLITSLKDREMSYNAIEFFN---VPFSFDERLTLTNFSV 201 Query: 555 EAGGKNGVV 581 EA K ++ Sbjct: 202 EANAKTAII 210
>ACON_SCHPO (O13966) Aconitate hydratase, mitochondrial precursor (EC 4.2.1.3)| (Citrate hydro-lyase) (Aconitase) Length = 778 Score = 89.0 bits (219), Expect = 1e-17 Identities = 50/137 (36%), Positives = 72/137 (52%) Frame = +3 Query: 198 GVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFATGIGNTDAGFVMGTGKALLKVPPT 377 G+ H + E + PG +L+GTDSHT NAG G A G+G DA VM LK P Sbjct: 167 GIIH-QIVLENYAFPGGLLIGTDSHTPNAGGLGMVAIGVGGADAVDVMANLPWELKCPKV 225 Query: 378 IRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIE 557 I L G++ + KD+IL++ G ++V G T +E+ G +ESL+ T+CNM E Sbjct: 226 IGVKLTGQLKGWTSPKDVILKVAGILTVKGGTGAIVEYFGPGVESLSCTGMGTICNMGAE 285 Query: 558 AGGKNGVVPADETTFKY 608 G + P + +Y Sbjct: 286 IGATTSIFPFNPRMSEY 302
>ACON_CAEEL (P34455) Probable aconitate hydratase, mitochondrial precursor (EC| 4.2.1.3) (Citrate hydro-lyase) (Aconitase) Length = 777 Score = 88.2 bits (217), Expect = 2e-17 Identities = 49/137 (35%), Positives = 73/137 (53%) Frame = +3 Query: 198 GVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFATGIGNTDAGFVMGTGKALLKVPPT 377 G+ H + E + PG +L+GTDSHT N G G G+G DA VM LK P Sbjct: 168 GIIH-QIILENYAFPGLLLIGTDSHTPNGGGLGGLCIGVGGADAVDVMADIPWELKCPKV 226 Query: 378 IRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIE 557 I L G++ + AKD+IL++ ++V G T +E+ G ++S++ T+CNM E Sbjct: 227 IGIKLTGKLNGWTSAKDVILKVADILTVKGGTGAIVEYFGPGVDSISATGMGTICNMGAE 286 Query: 558 AGGKNGVVPADETTFKY 608 G V P +E+ +KY Sbjct: 287 IGATTSVFPYNESMYKY 303
>LYS4_EMENI (Q92412) Homoaconitase, mitochondrial precursor (EC 4.2.1.36)| (Homoaconitate hydratase) Length = 775 Score = 87.4 bits (215), Expect = 3e-17 Identities = 46/137 (33%), Positives = 73/137 (53%), Gaps = 2/137 (1%) Frame = +3 Query: 186 PDYKGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFATGIGNTDAGFVMGTGKALLK 365 P +G+ H + +EG PG + + +DSH+ G G T I TDA V TGK + Sbjct: 161 PAGRGIGHQIMIEEGFAWPGTLAVASDSHSNMYGGVGCLGTPIVRTDAASVWATGKTWWQ 220 Query: 366 VPPTIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSMEFVGS--TIESLTMEERMTL 539 +PP + G +PP + KD+I+ + G + ++EF GS T+ SL+++ R+T+ Sbjct: 221 IPPVAKVTFKGVLPPGVTGKDVIVALCGLFNKDDVLNHAIEFTGSEETMRSLSVDTRLTI 280 Query: 540 CNMVIEAGGKNGVVPAD 590 NM E G +G+ P D Sbjct: 281 ANMTTEWGALSGLFPID 297
>LYS4_YEAST (P49367) Homoaconitase, mitochondrial precursor (EC 4.2.1.36)| (Homoaconitate hydratase) Length = 693 Score = 87.0 bits (214), Expect = 4e-17 Identities = 41/137 (29%), Positives = 74/137 (54%) Frame = +3 Query: 186 PDYKGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFATGIGNTDAGFVMGTGKALLK 365 P +G+ H + +EG+ P + + +DSH+ G G T I TDA + TG+ + Sbjct: 116 PAGRGIGHQIMIEEGYAFPLNMTVASDSHSNTYGGLGSLGTPIVRTDAAAIWATGQTWWQ 175 Query: 366 VPPTIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCN 545 +PP + L G++P + KD+I+ + G + ++EF G ++ +L ++ R+T+ N Sbjct: 176 IPPVAQVELKGQLPQGVSGKDIIVALCGLFNNDQVLNHAIEFTGDSLNALPIDHRLTIAN 235 Query: 546 MVIEAGGKNGVVPADET 596 M E G +G+ P D+T Sbjct: 236 MTTEWGALSGLFPVDKT 252
>ACON_PIG (P16276) Aconitate hydratase, mitochondrial precursor (EC 4.2.1.3)| (Citrate hydro-lyase) (Aconitase) Length = 781 Score = 84.0 bits (206), Expect = 3e-16 Identities = 48/137 (35%), Positives = 69/137 (50%) Frame = +3 Query: 198 GVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFATGIGNTDAGFVMGTGKALLKVPPT 377 G+ H + E + PG +L+GTDSHT N G G G+G DA VM LK P Sbjct: 171 GIIH-QIILENYAYPGVLLIGTDSHTPNGGGLGGICIGVGGADAVDVMAGIPWELKCPKV 229 Query: 378 IRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIE 557 I L G + + KD+IL++ G ++V G T +E+ G ++S++ T+CNM E Sbjct: 230 IGVKLTGSLSGWTSPKDVILKVAGILTVKGGTGAIVEYHGPGVDSISCTGMATICNMGAE 289 Query: 558 AGGKNGVVPADETTFKY 608 G V P + KY Sbjct: 290 IGATTSVFPYNHRMKKY 306
>ACON_MOUSE (Q99KI0) Aconitate hydratase, mitochondrial precursor (EC 4.2.1.3)| (Citrate hydro-lyase) (Aconitase) Length = 780 Score = 84.0 bits (206), Expect = 3e-16 Identities = 48/137 (35%), Positives = 69/137 (50%) Frame = +3 Query: 198 GVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFATGIGNTDAGFVMGTGKALLKVPPT 377 G+ H + E + PG +L+GTDSHT N G G G+G DA VM LK P Sbjct: 171 GIIH-QIILENYAYPGVLLIGTDSHTPNGGGLGGICIGVGGADAVDVMAGIPWELKCPKV 229 Query: 378 IRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIE 557 I L G + + KD+IL++ G ++V G T +E+ G ++S++ T+CNM E Sbjct: 230 IGVKLTGSLSGWTSPKDVILKVAGILTVKGGTGAIVEYHGPGVDSISCTGMATICNMGAE 289 Query: 558 AGGKNGVVPADETTFKY 608 G V P + KY Sbjct: 290 IGATTSVFPYNHRMKKY 306
>ACON_GRAVE (P49609) Aconitate hydratase, mitochondrial precursor (EC 4.2.1.3)| (Citrate hydro-lyase) (Aconitase) Length = 779 Score = 84.0 bits (206), Expect = 3e-16 Identities = 52/152 (34%), Positives = 77/152 (50%), Gaps = 10/152 (6%) Frame = +3 Query: 159 KDLSDFRANPDYK----------GVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFAT 308 K++ DF A+ K G+ H + E + PG +++GTDSHT NAG G A Sbjct: 146 KEVYDFLASAGAKYGLGFWKPGSGIIH-QIVLENYAFPGLLMIGTDSHTPNAGGLGACAV 204 Query: 309 GIGNTDAGFVMGTGKALLKVPPTIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSME 488 G+G DA VM LK P I L G++ + KD+IL++ G ++V G T +E Sbjct: 205 GVGGADAVDVMVGLPWELKAPKVIGVKLTGKLQEWASPKDVILKVAGILTVKGGTGAIVE 264 Query: 489 FVGSTIESLTMEERMTLCNMVIEAGGKNGVVP 584 + G ++SL+ T+CNM E G + P Sbjct: 265 YFGEGVDSLSCTGMGTICNMGAEIGATTSMFP 296
>ACON_RAT (Q9ER34) Aconitate hydratase, mitochondrial precursor (EC 4.2.1.3)| (Citrate hydro-lyase) (Aconitase) Length = 780 Score = 83.6 bits (205), Expect = 4e-16 Identities = 48/137 (35%), Positives = 69/137 (50%) Frame = +3 Query: 198 GVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFATGIGNTDAGFVMGTGKALLKVPPT 377 G+ H + E + PG +L+GTDSHT N G G G+G DA VM LK P Sbjct: 171 GIIH-QIILENYAYPGVLLIGTDSHTPNGGGLGGICIGVGGADAVDVMAGIPWELKCPKV 229 Query: 378 IRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIE 557 I L G + + KD+IL++ G ++V G T +E+ G ++S++ T+CNM E Sbjct: 230 IGVKLTGTLSGWTSPKDVILKVAGILTVKGGTGAIVEYHGPGVDSISCTGMATICNMGAE 289 Query: 558 AGGKNGVVPADETTFKY 608 G V P + KY Sbjct: 290 IGATTSVFPYNHRMKKY 306
>ACON_HUMAN (Q99798) Aconitate hydratase, mitochondrial precursor (EC 4.2.1.3)| (Citrate hydro-lyase) (Aconitase) Length = 780 Score = 83.6 bits (205), Expect = 4e-16 Identities = 48/137 (35%), Positives = 69/137 (50%) Frame = +3 Query: 198 GVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFATGIGNTDAGFVMGTGKALLKVPPT 377 G+ H + E + PG +L+GTDSHT N G G G+G DA VM LK P Sbjct: 171 GIIH-QIILENYAYPGVLLIGTDSHTPNGGGLGGICIGVGGADAVDVMAGIPWELKCPKV 229 Query: 378 IRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIE 557 I L G + + KD+IL++ G ++V G T +E+ G ++S++ T+CNM E Sbjct: 230 IGVKLTGSLSGWSSPKDVILKVAGILTVKGGTGAIVEYHGPGVDSISCTGMATICNMGAE 289 Query: 558 AGGKNGVVPADETTFKY 608 G V P + KY Sbjct: 290 IGATTSVFPYNHRMKKY 306
>LEU2_PYRHO (O59391) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 380 Score = 83.6 bits (205), Expect = 4e-16 Identities = 41/129 (31%), Positives = 70/129 (54%) Frame = +3 Query: 195 KGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFATGIGNTDAGFVMGTGKALLKVPP 374 KG+ H + + G +++G DSHT GA G FA G+G TD V+G GK L+VP Sbjct: 85 KGISHQLVVEMGLAEKSRIVVGGDSHTPTLGALGVFAVGMGATDVAVVLGLGKTWLRVPE 144 Query: 375 TIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVI 554 ++ + +G+ +A D+++++I + Y+++EF T +ER+TL N + Sbjct: 145 SVAVIFEGKPSRTTMAADVMIRLITSLRNYDMNYKALEFFN---VPFTADERLTLTNFSV 201 Query: 555 EAGGKNGVV 581 EA K ++ Sbjct: 202 EANAKTALI 210
>LEU2_PYRKO (Q5JFV6) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 380 Score = 82.8 bits (203), Expect = 7e-16 Identities = 43/129 (33%), Positives = 67/129 (51%) Frame = +3 Query: 195 KGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFATGIGNTDAGFVMGTGKALLKVPP 374 +G+ H + G +++G DSHT GA G FA GIG TD VMG GK +VP Sbjct: 85 QGISHQLAVEMGLADNARIVVGADSHTPTLGALGVFAVGIGATDTAVVMGLGKTWFRVPE 144 Query: 375 TIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVI 554 ++ V +G ++A D ++ II + Y+++EF + +ER+TL N + Sbjct: 145 SVSVVFEGRPGKNVMAADAMIHIITALRDFEMNYKAIEFFN---VPFSFDERLTLTNFSV 201 Query: 555 EAGGKNGVV 581 EA K G++ Sbjct: 202 EANAKTGII 210
>LYS4_CANGA (Q6FM51) Homoaconitase, mitochondrial precursor (EC 4.2.1.36)| (Homoaconitate hydratase) Length = 689 Score = 82.0 bits (201), Expect = 1e-15 Identities = 39/141 (27%), Positives = 72/141 (51%) Frame = +3 Query: 186 PDYKGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFATGIGNTDAGFVMGTGKALLK 365 P +G+ H + +EG+ P + + +DSH+ G G T + TDA + TG+ + Sbjct: 113 PAGRGIGHQIMVEEGYAFPLNLTVASDSHSNTYGGMGALGTPVVRTDAAAIWATGQTWWQ 172 Query: 366 VPPTIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCN 545 +PP + G++ + KD+I+ + G + ++EF G I+ L ++ R+T+ N Sbjct: 173 IPPVAQVEFKGKLHESVSGKDIIVALCGVFNKDQVLNHAIEFTGDAIKHLPVDFRLTIAN 232 Query: 546 MVIEAGGKNGVVPADETTFKY 608 M E G +G+ P D+T + Sbjct: 233 MTTEWGALSGLFPVDDTLINW 253
>ACON_BOVIN (P20004) Aconitate hydratase, mitochondrial precursor (EC 4.2.1.3)| (Citrate hydro-lyase) (Aconitase) Length = 780 Score = 81.6 bits (200), Expect = 2e-15 Identities = 47/137 (34%), Positives = 68/137 (49%) Frame = +3 Query: 198 GVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFATGIGNTDAGFVMGTGKALLKVPPT 377 G+ H + E + PG +L+GTDSHT N G G G+G DA V LK P Sbjct: 171 GIIH-QIILENYAYPGVLLIGTDSHTPNGGGLGGICIGVGGADAVDVTAGIPWELKCPKV 229 Query: 378 IRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIE 557 I L G + + KD+IL++ G ++V G T +E+ G ++S++ T+CNM E Sbjct: 230 IGVKLTGSLSGWTSPKDVILKVAGILTVKGGTGAIVEYHGPGVDSISCTGMATICNMGAE 289 Query: 558 AGGKNGVVPADETTFKY 608 G V P + KY Sbjct: 290 IGATTSVFPYNHRMKKY 306
>LEU2_SULAC (Q4JC09) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 414 Score = 81.3 bits (199), Expect = 2e-15 Identities = 48/163 (29%), Positives = 78/163 (47%) Frame = +3 Query: 120 FCQEQKIKYFYDIKDLSDFRANPDYKGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQ 299 F ++ + FYDI G+ H + E + PG+V++ DSHT +GA G Sbjct: 84 FVKKTSVPNFYDINS-----------GILHQIMI-ERYANPGQVIVAADSHTSTSGAVGA 131 Query: 300 FATGIGNTDAGFVMGTGKALLKVPPTIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYR 479 FA G+G +D + TGK + VP + L+G+ ++ KD+ L+I+G+ Sbjct: 132 FAQGLGASDVAAAVITGKTWVMVPQPFKITLEGKPARWINGKDIALKILGDFKADYFNGM 191 Query: 480 SMEFVGSTIESLTMEERMTLCNMVIEAGGKNGVVPADETTFKY 608 S+E ++ M+ R T+ NM IE + D+ TF Y Sbjct: 192 SLEIFVKEPSAVPMDFRATVSNMGIEMNADALMFVPDQETFNY 234
>LEU2_PYRAE (Q8ZW41) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 415 Score = 80.5 bits (197), Expect = 4e-15 Identities = 46/137 (33%), Positives = 69/137 (50%) Frame = +3 Query: 198 GVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFATGIGNTDAGFVMGTGKALLKVPPT 377 G+ H + E + PG+V+ DSHT AGA G FA G+G TD + GK + VP Sbjct: 98 GILH-QIILEKYALPGQVIFAADSHTNTAGAVGAFAHGMGATDIAAALKLGKTWIVVPAP 156 Query: 378 IRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIE 557 R + GE P ++ KD+ L ++G+ G S+E T ++ M++R T+ NM E Sbjct: 157 FRIDVVGEFPIGVMGKDVALHLLGQFGAEGFNGYSVEVFVETPKAFPMDDRATVANMSTE 216 Query: 558 AGGKNGVVPADETTFKY 608 G + D T +Y Sbjct: 217 MGADALMFIPDVITAEY 233
>LEU2_SULSO (Q97VY2) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 416 Score = 80.1 bits (196), Expect = 5e-15 Identities = 49/163 (30%), Positives = 79/163 (48%) Frame = +3 Query: 120 FCQEQKIKYFYDIKDLSDFRANPDYKGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQ 299 F + + I FYDI G+ H + ++ + PG+V+L DSHT +GA G Sbjct: 86 FVKSEGIPNFYDIN-----------YGILHEVMIEQ-YANPGQVILAADSHTTTSGAVGA 133 Query: 300 FATGIGNTDAGFVMGTGKALLKVPPTIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYR 479 FA G+G +D + TGK L VP + VL+G+ ++ KD+ L+++G+ Sbjct: 134 FAQGMGASDIAAALITGKTWLVVPQPFKVVLEGKPAKWITGKDVALKLLGDFKADYFNGM 193 Query: 480 SMEFVGSTIESLTMEERMTLCNMVIEAGGKNGVVPADETTFKY 608 ++E S M+ R T+ NM IE + D+ T +Y Sbjct: 194 TLEIFVKDPLSFPMDYRATVSNMGIEMNADALMFIPDQETKRY 236
>LEU2_SULTO (Q974R0) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 415 Score = 79.3 bits (194), Expect = 8e-15 Identities = 50/163 (30%), Positives = 79/163 (48%) Frame = +3 Query: 120 FCQEQKIKYFYDIKDLSDFRANPDYKGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQ 299 F +E KI F+DI G+ H L ++ + PG V++ DSHT +GA G Sbjct: 84 FVKELKIPNFHDIN-----------VGILHQILLEK-YANPGYVIVAADSHTTTSGAVGA 131 Query: 300 FATGIGNTDAGFVMGTGKALLKVPPTIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYR 479 FA G+G +D + TGK + VP + + +L+G+ ++ KD+ L+I+G+ Sbjct: 132 FAQGLGASDVAAAVITGKTWVMVPQSFKIMLEGKPGKWINGKDVALKILGDFKADYFNGM 191 Query: 480 SMEFVGSTIESLTMEERMTLCNMVIEAGGKNGVVPADETTFKY 608 S+E + M+ R T+ NM IE + DE T Y Sbjct: 192 SIEIFVREPSAFPMDFRATVSNMGIEMNADALMFVPDEETVNY 234
>ACON2_YEAST (P39533) Putative aconitase in PRP21-UBP12 intergenic region (EC| 4.2.1.3) Length = 789 Score = 78.6 bits (192), Expect = 1e-14 Identities = 45/137 (32%), Positives = 67/137 (48%) Frame = +3 Query: 198 GVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFATGIGNTDAGFVMGTGKALLKVPPT 377 G+ H + E PG ++LGTDSHT NAG G A G+G DA + LK P Sbjct: 168 GIIH-QIVLENFSAPGLMMLGTDSHTPNAGGLGAIAIGVGGADAVDALTGTPWELKAPKI 226 Query: 378 IRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIE 557 + L G++ + KD+I ++ G ++V G T +E+ G + +L+ T+CNM E Sbjct: 227 LGVKLTGKLNGWSTPKDVITKLAGLLTVRGGTGYIVEYFGEGVSTLSCTGMATICNMGAE 286 Query: 558 AGGKNGVVPADETTFKY 608 G P E +Y Sbjct: 287 IGATTSTFPYQEAHKRY 303
>ACON_CORDI (Q6NH63) Aconitate hydratase (EC 4.2.1.3)| Length = 934 Score = 75.1 bits (183), Expect = 1e-13 Identities = 47/159 (29%), Positives = 71/159 (44%), Gaps = 9/159 (5%) Frame = +3 Query: 159 KDLSDFRANPDYKGVCH---------IALAQEGHCRPGEVLLGTDSHTCNAGAFGQFATG 311 K S+FR P G+ H + G P + +GTDSHT G G Sbjct: 162 KAFSNFRVVPPGTGIVHQVNIENLARVVFDNNGLAYP-DTCIGTDSHTTMENGLGILGWG 220 Query: 312 IGNTDAGFVMGTGKALLKVPPTIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSMEF 491 +G +A M + +P + F L GE+P + A D++L I + G + +EF Sbjct: 221 VGGIEAEAAMLGQPVSMLIPRVVGFKLTGEIPAGVTATDVVLTITEMLREHGVVQKFVEF 280 Query: 492 VGSTIESLTMEERMTLCNMVIEAGGKNGVVPADETTFKY 608 G+ ++S+ + R T+ NM E G + P DE T KY Sbjct: 281 YGNGVKSIPLANRATIGNMSPEFGSTCAIFPIDEETVKY 319
>ACON_CORGL (Q8NQ98) Aconitate hydratase (EC 4.2.1.3)| Length = 939 Score = 73.9 bits (180), Expect = 3e-13 Identities = 47/159 (29%), Positives = 72/159 (45%), Gaps = 9/159 (5%) Frame = +3 Query: 159 KDLSDFRANPDYKGVCH---------IALAQEGHCRPGEVLLGTDSHTCNAGAFGQFATG 311 + S+FR P G+ H + EG P + +GTDSHT G G Sbjct: 162 ESFSNFRVVPPGTGIVHQVNIEYLARVVFDNEGLAYP-DTCIGTDSHTTMENGLGILGWG 220 Query: 312 IGNTDAGFVMGTGKALLKVPPTIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSMEF 491 +G +A M + +P + F L GE+P + A D++L I + G + +EF Sbjct: 221 VGGIEAEAAMLGQPVSMLIPRVVGFKLTGEIPVGVTATDVVLTITEMLRDHGVVQKFVEF 280 Query: 492 VGSTIESLTMEERMTLCNMVIEAGGKNGVVPADETTFKY 608 GS ++++ + R T+ NM E G + P DE T KY Sbjct: 281 YGSGVKAVPLANRATIGNMSPEFGSTCAMFPIDEETTKY 319
>ACON_COREF (Q8FTA8) Aconitate hydratase (EC 4.2.1.3)| Length = 937 Score = 73.2 bits (178), Expect = 6e-13 Identities = 46/156 (29%), Positives = 71/156 (45%), Gaps = 9/156 (5%) Frame = +3 Query: 168 SDFRANPDYKGVCH---------IALAQEGHCRPGEVLLGTDSHTCNAGAFGQFATGIGN 320 S+FR P G+ H + +G P + +GTDSHT G G+G Sbjct: 165 SNFRVVPPGTGIVHQVNIEYLARVVFDNDGLAYP-DTCIGTDSHTTMENGLGILGWGVGG 223 Query: 321 TDAGFVMGTGKALLKVPPTIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSMEFVGS 500 +A M + +P + F L GE+P + A D++L I + G + +EF G+ Sbjct: 224 IEAEAAMLGQPVSMLIPRVVGFKLTGEIPVGVTATDVVLTITEMLRDHGVVQKFVEFYGN 283 Query: 501 TIESLTMEERMTLCNMVIEAGGKNGVVPADETTFKY 608 ++S+ + R T+ NM E G + P DE T KY Sbjct: 284 GVKSVPLANRATIGNMSPEFGSTCAMFPIDEETIKY 319
>ACON_LEGPH (P37032) Aconitate hydratase (EC 4.2.1.3) (Citrate hydro-lyase)| (Aconitase) (Major iron-containing protein) (MICP) (IP210) Length = 891 Score = 72.8 bits (177), Expect = 7e-13 Identities = 48/163 (29%), Positives = 72/163 (44%), Gaps = 13/163 (7%) Frame = +3 Query: 159 KDLSDFRANPDYKGVCH-IALAQEG------------HCRPGEVLLGTDSHTCNAGAFGQ 299 K S+F+ P G+CH + L G + P + L+GTDSHT G Sbjct: 167 KAFSNFQVVPPGTGICHQVNLEYLGKTVWNSENDGQLYAYP-DTLVGTDSHTTMINGLGV 225 Query: 300 FATGIGNTDAGFVMGTGKALLKVPPTIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYR 479 G+G +A M + +P I F L G++ + A DL+L + + G + Sbjct: 226 LGWGVGGIEAEAAMLGQPVSMLIPEVIGFKLSGKLKEGITATDLVLTVTQMLRKKGVVGK 285 Query: 480 SMEFVGSTIESLTMEERMTLCNMVIEAGGKNGVVPADETTFKY 608 +EF G + L + +R T+ NM E G G P D+ T KY Sbjct: 286 FVEFYGPGLNDLPLADRATISNMAPEYGATCGFFPVDKETIKY 328
>ACON_STRMU (Q59938) Aconitate hydratase (EC 4.2.1.3) (Citrate hydro-lyase)| (Aconitase) Length = 888 Score = 72.4 bits (176), Expect = 1e-12 Identities = 44/159 (27%), Positives = 71/159 (44%), Gaps = 9/159 (5%) Frame = +3 Query: 159 KDLSDFRANPDYKGVCH---------IALAQEGHCRPGEVLLGTDSHTCNAGAFGQFATG 311 K ++RA P G+ H + + ++G P + + GTDSHT G G Sbjct: 160 KTFENYRAVPPATGIIHQVNLEFLSDVIINKDGFLYP-DSMFGTDSHTTMINGIGVLGWG 218 Query: 312 IGNTDAGFVMGTGKALLKVPPTIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSMEF 491 +G +A M + +P I L GE+P A DL L++ ++ + + +EF Sbjct: 219 VGGIEAEAAMLGEASYFPIPEVIGVRLYGELPKVATATDLALKVTQKLRLENVVGKFVEF 278 Query: 492 VGSTIESLTMEERMTLCNMVIEAGGKNGVVPADETTFKY 608 G + L++ +R T+ NM E G G P D+ T Y Sbjct: 279 FGPGLAGLSLADRATVANMAPEYGATCGYFPIDDETLNY 317
>ACON1_ECOLI (P25516) Aconitate hydratase 1 (EC 4.2.1.3) (Citrate hydro-lyase 1)| (Aconitase 1) Length = 890 Score = 70.1 bits (170), Expect = 5e-12 Identities = 46/159 (28%), Positives = 68/159 (42%), Gaps = 12/159 (7%) Frame = +3 Query: 168 SDFRANPDYKGVCH------IALAQEGHCRPGE------VLLGTDSHTCNAGAFGQFATG 311 S F P G+CH + A + GE L+GTDSHT G G Sbjct: 167 SRFSVVPPGTGICHQVNLEYLGKAVWSELQDGEWIAYPDTLVGTDSHTTMINGLGVLGWG 226 Query: 312 IGNTDAGFVMGTGKALLKVPPTIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSMEF 491 +G +A M + +P + F L G++ + A DL+L + + G + +EF Sbjct: 227 VGGIEAEAAMLGQPVSMLIPDVVGFKLTGKLREGITATDLVLTVTQMLRKHGVVGKFVEF 286 Query: 492 VGSTIESLTMEERMTLCNMVIEAGGKNGVVPADETTFKY 608 G ++SL + +R T+ NM E G G P D T Y Sbjct: 287 YGDGLDSLPLADRATIANMSPEYGATCGFFPIDAVTLDY 325
>IREB1_RABIT (Q01059) Iron-responsive element-binding protein 1 (IRE-BP 1) (Iron| regulatory protein 1) (IRP1) (Ferritin repressor protein) (Aconitate hydratase) (EC 4.2.1.3) (Citrate hydro-lyase) (Aconitase) Length = 889 Score = 68.6 bits (166), Expect = 1e-11 Identities = 45/159 (28%), Positives = 71/159 (44%), Gaps = 9/159 (5%) Frame = +3 Query: 159 KDLSDFRANPDYKGVCH---------IALAQEGHCRPGEVLLGTDSHTCNAGAFGQFATG 311 K + R P G+ H + Q+G+ P + L+GTDSHT G G Sbjct: 162 KAFRNMRIIPPGSGIIHQVNLEYLARVVFDQDGYYYP-DSLVGTDSHTTMIDGLGVLGWG 220 Query: 312 IGNTDAGFVMGTGKALLKVPPTIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSMEF 491 +G +A VM + +P I + L G+ P + + D++L I + G + +EF Sbjct: 221 VGGIEAEAVMLGQPISMVLPQVIGYRLMGKPHPLVTSTDIVLTITKHLRQVGVVGKFVEF 280 Query: 492 VGSTIESLTMEERMTLCNMVIEAGGKNGVVPADETTFKY 608 G + L++ +R T+ NM E G P DE + KY Sbjct: 281 FGLGVAQLSIADRATIANMCPEYGATATFFPVDEVSIKY 319
>ACON_STAES (Q8CPC2) Aconitate hydratase (EC 4.2.1.3) (Citrate hydro-lyase)| (Aconitase) Length = 901 Score = 68.2 bits (165), Expect = 2e-11 Identities = 47/162 (29%), Positives = 68/162 (41%), Gaps = 12/162 (7%) Frame = +3 Query: 159 KDLSDFRANPDYKGVCHIA----LAQEGHCRP--------GEVLLGTDSHTCNAGAFGQF 302 K ++ A P G+ H LA H R + L+GTDSHT G Sbjct: 165 KAFDNYNAVPPATGIVHQVNLEYLANVVHVRDVDGEKTAFPDTLVGTDSHTTMINGIGVL 224 Query: 303 ATGIGNTDAGFVMGTGKALLKVPPTIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRS 482 G+G +A M + +P I L +P A DL L++ E+ G + Sbjct: 225 GWGVGGIEAEAGMLGQPSYFPIPEVIGVRLTHSLPQGSTATDLALRVTEELRKKGVVGKF 284 Query: 483 MEFVGSTIESLTMEERMTLCNMVIEAGGKNGVVPADETTFKY 608 +EF G ++ L + +R T+ NM E G G P DE + KY Sbjct: 285 VEFFGPGVQHLPLADRATIANMAPEYGATCGFFPVDEESLKY 326
>ACON_STAEQ (Q5HPJ0) Aconitate hydratase (EC 4.2.1.3) (Citrate hydro-lyase)| (Aconitase) Length = 901 Score = 68.2 bits (165), Expect = 2e-11 Identities = 47/162 (29%), Positives = 68/162 (41%), Gaps = 12/162 (7%) Frame = +3 Query: 159 KDLSDFRANPDYKGVCHIA----LAQEGHCRP--------GEVLLGTDSHTCNAGAFGQF 302 K ++ A P G+ H LA H R + L+GTDSHT G Sbjct: 165 KAFDNYNAVPPATGIVHQVNLEYLANVVHVRDVDGEKTAFPDTLVGTDSHTTMINGIGVL 224 Query: 303 ATGIGNTDAGFVMGTGKALLKVPPTIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRS 482 G+G +A M + +P I L +P A DL L++ E+ G + Sbjct: 225 GWGVGGIEAEAGMLGQPSYFPIPEVIGVRLTHSLPQGSTATDLALRVTEELRKKGVVGKF 284 Query: 483 MEFVGSTIESLTMEERMTLCNMVIEAGGKNGVVPADETTFKY 608 +EF G ++ L + +R T+ NM E G G P DE + KY Sbjct: 285 VEFFGPGVQHLPLADRATIANMAPEYGATCGFFPVDEESLKY 326
>ACON_FRATH (Q2A1K3) Aconitate hydratase (EC 4.2.1.3) (Citrate hydro-lyase)| (Aconitase) Length = 937 Score = 67.4 bits (163), Expect = 3e-11 Identities = 36/121 (29%), Positives = 59/121 (48%) Frame = +3 Query: 246 EVLLGTDSHTCNAGAFGQFATGIGNTDAGFVMGTGKALLKVPPTIRFVLDGEMPPYLLAK 425 + L+GTDSHT G G+G +A VM + +P + G++ + A Sbjct: 206 DTLVGTDSHTTMINGVGAVGWGVGGIEAEAVMLGQPYYMVLPDVVGVKFTGKLKTGVTAT 265 Query: 426 DLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGVVPADETTFK 605 DL+L++ + G + +E+ G +ESL++ +R T+ NM E G G P DE T Sbjct: 266 DLVLKVTEVLRKHGVVGKFVEYYGEGLESLSLPDRATIANMTPEYGATIGFFPVDEVTLD 325 Query: 606 Y 608 + Sbjct: 326 F 326
>ACON_STAAW (P63434) Aconitate hydratase (EC 4.2.1.3) (Citrate hydro-lyase)| (Aconitase) Length = 901 Score = 67.4 bits (163), Expect = 3e-11 Identities = 46/162 (28%), Positives = 68/162 (41%), Gaps = 12/162 (7%) Frame = +3 Query: 159 KDLSDFRANPDYKGVCHIA----LAQEGHCRP--------GEVLLGTDSHTCNAGAFGQF 302 K ++ A P G+ H LA H R + L+GTDSHT G Sbjct: 165 KAFDNYNAVPPATGIVHQVNLEYLASVVHVRDVDGEKTAFPDTLVGTDSHTTMINGIGVL 224 Query: 303 ATGIGNTDAGFVMGTGKALLKVPPTIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRS 482 G+G +A M + +P I L +P A DL L++ E+ G + Sbjct: 225 GWGVGGIEAEAGMLGQPSYFPIPEVIGVRLVNSLPQGATATDLALRVTQELRKKGVVGKF 284 Query: 483 MEFVGSTIESLTMEERMTLCNMVIEAGGKNGVVPADETTFKY 608 +EF G ++ L + +R T+ NM E G G P D+ + KY Sbjct: 285 VEFFGPGVQHLPLADRATIANMAPEYGATCGFFPVDDESLKY 326
>ACON_STAAS (Q6G9K9) Aconitate hydratase (EC 4.2.1.3) (Citrate hydro-lyase)| (Aconitase) Length = 901 Score = 67.4 bits (163), Expect = 3e-11 Identities = 46/162 (28%), Positives = 68/162 (41%), Gaps = 12/162 (7%) Frame = +3 Query: 159 KDLSDFRANPDYKGVCHIA----LAQEGHCRP--------GEVLLGTDSHTCNAGAFGQF 302 K ++ A P G+ H LA H R + L+GTDSHT G Sbjct: 165 KAFDNYNAVPPATGIVHQVNLEYLASVVHVRDVDGEKTAFPDTLVGTDSHTTMINGIGVL 224 Query: 303 ATGIGNTDAGFVMGTGKALLKVPPTIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRS 482 G+G +A M + +P I L +P A DL L++ E+ G + Sbjct: 225 GWGVGGIEAEAGMLGQPSYFPIPEVIGVRLVNSLPQGATATDLALRVTQELRKKGVVGKF 284 Query: 483 MEFVGSTIESLTMEERMTLCNMVIEAGGKNGVVPADETTFKY 608 +EF G ++ L + +R T+ NM E G G P D+ + KY Sbjct: 285 VEFFGPGVQHLPLADRATIANMAPEYGATCGFFPVDDESLKY 326
>ACON_STAAR (Q6GH55) Aconitate hydratase (EC 4.2.1.3) (Citrate hydro-lyase)| (Aconitase) Length = 901 Score = 67.4 bits (163), Expect = 3e-11 Identities = 46/162 (28%), Positives = 68/162 (41%), Gaps = 12/162 (7%) Frame = +3 Query: 159 KDLSDFRANPDYKGVCHIA----LAQEGHCRP--------GEVLLGTDSHTCNAGAFGQF 302 K ++ A P G+ H LA H R + L+GTDSHT G Sbjct: 165 KAFDNYNAVPPATGIVHQVNLEYLASVVHVRDVDGEKTAFPDTLVGTDSHTTMINGIGVL 224 Query: 303 ATGIGNTDAGFVMGTGKALLKVPPTIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRS 482 G+G +A M + +P I L +P A DL L++ E+ G + Sbjct: 225 GWGVGGIEAEAGMLGQPSYFPIPEVIGVRLVNSLPQGATATDLALRVTQELRKKGVVGKF 284 Query: 483 MEFVGSTIESLTMEERMTLCNMVIEAGGKNGVVPADETTFKY 608 +EF G ++ L + +R T+ NM E G G P D+ + KY Sbjct: 285 VEFFGPGVQHLPLADRATIANMAPEYGATCGFFPVDDESLKY 326
>ACON_STAAN (P99148) Aconitate hydratase (EC 4.2.1.3) (Citrate hydro-lyase)| (Aconitase) Length = 901 Score = 67.4 bits (163), Expect = 3e-11 Identities = 46/162 (28%), Positives = 68/162 (41%), Gaps = 12/162 (7%) Frame = +3 Query: 159 KDLSDFRANPDYKGVCHIA----LAQEGHCRP--------GEVLLGTDSHTCNAGAFGQF 302 K ++ A P G+ H LA H R + L+GTDSHT G Sbjct: 165 KAFDNYNAVPPATGIVHQVNLEYLASVVHVRDVDGEKTAFPDTLVGTDSHTTMINGIGVL 224 Query: 303 ATGIGNTDAGFVMGTGKALLKVPPTIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRS 482 G+G +A M + +P I L +P A DL L++ E+ G + Sbjct: 225 GWGVGGIEAEAGMLGQPSYFPIPEVIGVRLVNSLPQGATATDLALRVTQELRKKGVVGKF 284 Query: 483 MEFVGSTIESLTMEERMTLCNMVIEAGGKNGVVPADETTFKY 608 +EF G ++ L + +R T+ NM E G G P D+ + KY Sbjct: 285 VEFFGPGVQHLPLADRATIANMAPEYGATCGFFPVDDESLKY 326
>ACON_STAAM (P63433) Aconitate hydratase (EC 4.2.1.3) (Citrate hydro-lyase)| (Aconitase) Length = 901 Score = 67.4 bits (163), Expect = 3e-11 Identities = 46/162 (28%), Positives = 68/162 (41%), Gaps = 12/162 (7%) Frame = +3 Query: 159 KDLSDFRANPDYKGVCHIA----LAQEGHCRP--------GEVLLGTDSHTCNAGAFGQF 302 K ++ A P G+ H LA H R + L+GTDSHT G Sbjct: 165 KAFDNYNAVPPATGIVHQVNLEYLASVVHVRDVDGEKTAFPDTLVGTDSHTTMINGIGVL 224 Query: 303 ATGIGNTDAGFVMGTGKALLKVPPTIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRS 482 G+G +A M + +P I L +P A DL L++ E+ G + Sbjct: 225 GWGVGGIEAEAGMLGQPSYFPIPEVIGVRLVNSLPQGATATDLALRVTQELRKKGVVGKF 284 Query: 483 MEFVGSTIESLTMEERMTLCNMVIEAGGKNGVVPADETTFKY 608 +EF G ++ L + +R T+ NM E G G P D+ + KY Sbjct: 285 VEFFGPGVQHLPLADRATIANMAPEYGATCGFFPVDDESLKY 326
>ACON_STAAC (Q5HG69) Aconitate hydratase (EC 4.2.1.3) (Citrate hydro-lyase)| (Aconitase) Length = 901 Score = 67.4 bits (163), Expect = 3e-11 Identities = 46/162 (28%), Positives = 68/162 (41%), Gaps = 12/162 (7%) Frame = +3 Query: 159 KDLSDFRANPDYKGVCHIA----LAQEGHCRP--------GEVLLGTDSHTCNAGAFGQF 302 K ++ A P G+ H LA H R + L+GTDSHT G Sbjct: 165 KAFDNYNAVPPATGIVHQVNLEYLASVVHVRDVDGEKTAFPDTLVGTDSHTTMINGIGVL 224 Query: 303 ATGIGNTDAGFVMGTGKALLKVPPTIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRS 482 G+G +A M + +P I L +P A DL L++ E+ G + Sbjct: 225 GWGVGGIEAEAGMLGQPSYFPIPEVIGVRLVNSLPQGATATDLALRVTQELRKKGVVGKF 284 Query: 483 MEFVGSTIESLTMEERMTLCNMVIEAGGKNGVVPADETTFKY 608 +EF G ++ L + +R T+ NM E G G P D+ + KY Sbjct: 285 VEFFGPGVQHLPLADRATIANMAPEYGATCGFFPVDDESLKY 326
>ACON_RICPR (Q9ZCF4) Aconitate hydratase (EC 4.2.1.3) (Citrate hydro-lyase)| (Aconitase) Length = 878 Score = 67.0 bits (162), Expect = 4e-11 Identities = 44/156 (28%), Positives = 69/156 (44%), Gaps = 9/156 (5%) Frame = +3 Query: 168 SDFRANPDYKGVCH---------IALAQEGHCRPGEVLLGTDSHTCNAGAFGQFATGIGN 320 ++F+ P G+CH + +G P + L+GTDSHT G+G Sbjct: 165 NNFKVVPPGTGICHQVNLEFLSQVVWHNDGTAYP-DSLVGTDSHTTMVNGLSVLGWGVGG 223 Query: 321 TDAGFVMGTGKALLKVPPTIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSMEFVGS 500 +A M + +P I L G++ A DL+L I + + +EF G+ Sbjct: 224 IEAESAMLGQPITMIIPEVIGVKLIGKLAGMATATDLVLTITEILRRKKVVGKFVEFFGN 283 Query: 501 TIESLTMEERMTLCNMVIEAGGKNGVVPADETTFKY 608 + +LT+ +R T+ NM E G G P D+ T KY Sbjct: 284 GLRNLTISDRATISNMSPEYGATCGFFPIDQETLKY 319
>ACON_CORJK (Q4JVM4) Aconitate hydratase (EC 4.2.1.3)| Length = 936 Score = 67.0 bits (162), Expect = 4e-11 Identities = 38/121 (31%), Positives = 56/121 (46%) Frame = +3 Query: 246 EVLLGTDSHTCNAGAFGQFATGIGNTDAGFVMGTGKALLKVPPTIRFVLDGEMPPYLLAK 425 + +GTDSHT G G+G +A M + +P + F L GE+P + A Sbjct: 199 DTCVGTDSHTTMENGLGILGWGVGGIEAEAAMLGQPISMLIPRVVGFKLTGEIPTGVTAT 258 Query: 426 DLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGVVPADETTFK 605 D++L I + G + +EF G + L + R T+ NM E G + P DE T K Sbjct: 259 DVVLTITDMLRQHGVVGKFVEFYGKGVGELPLANRATIGNMSPEFGSTAAMFPIDEETVK 318 Query: 606 Y 608 Y Sbjct: 319 Y 319
>IREB1_HUMAN (P21399) Iron-responsive element-binding protein 1 (IRE-BP 1) (Iron| regulatory protein 1) (IRP1) (Ferritin repressor protein) (Aconitate hydratase) (EC 4.2.1.3) (Citrate hydro-lyase) (Aconitase) Length = 889 Score = 66.2 bits (160), Expect = 7e-11 Identities = 39/136 (28%), Positives = 64/136 (47%) Frame = +3 Query: 201 VCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFATGIGNTDAGFVMGTGKALLKVPPTI 380 + + Q+G+ P + L+GTDSHT G G+G +A VM + +P I Sbjct: 185 LARVVFDQDGYYYP-DSLVGTDSHTTMIDGLGILGWGVGGIEAEAVMLGQPISMVLPQVI 243 Query: 381 RFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEA 560 + L G+ P + + D++L I + G + +EF G + L++ +R T+ NM E Sbjct: 244 GYRLMGKPHPLVTSTDIVLTITKHLRQVGVVGKFVEFFGPGVAQLSIADRATIANMCPEY 303 Query: 561 GGKNGVVPADETTFKY 608 G P DE + Y Sbjct: 304 GATAAFFPVDEVSITY 319
>IREB1_MOUSE (P28271) Iron-responsive element-binding protein 1 (IRE-BP 1) (Iron| regulatory protein 1) (IRP1) (Ferritin repressor protein) (Aconitate hydratase) (EC 4.2.1.3) (Citrate hydro-lyase) (Aconitase) Length = 889 Score = 65.9 bits (159), Expect = 9e-11 Identities = 39/136 (28%), Positives = 63/136 (46%) Frame = +3 Query: 201 VCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFATGIGNTDAGFVMGTGKALLKVPPTI 380 + + Q+G C + L+GTDSHT G G+G +A VM + +P I Sbjct: 185 LARVVFDQDG-CYYPDSLVGTDSHTTMIDGLGVLGWGVGGIEAEAVMLGQPISMVLPQVI 243 Query: 381 RFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEA 560 + L G+ P + + D++L I + G + +EF G + L++ +R T+ NM E Sbjct: 244 GYKLMGKPHPLVTSTDIVLTITKHLRQVGVVGKFVEFFGPGVAQLSIADRATIANMCPEY 303 Query: 561 GGKNGVVPADETTFKY 608 G P DE + Y Sbjct: 304 GATAAFFPVDEVSIAY 319
>ACON_BACSU (P09339) Aconitate hydratase (EC 4.2.1.3) (Citrate hydro-lyase)| (Aconitase) Length = 908 Score = 65.5 bits (158), Expect = 1e-10 Identities = 49/162 (30%), Positives = 69/162 (42%), Gaps = 12/162 (7%) Frame = +3 Query: 159 KDLSDFRANPDYKGVCHIA----LAQEGHC--RPGEV------LLGTDSHTCNAGAFGQF 302 K ++++A P G+ H LA H GE+ L+GTDSHT G Sbjct: 171 KAFNNYQAVPPATGIVHQVNLEFLASVVHAIEEDGELVTYPDTLVGTDSHTTMINGIGVL 230 Query: 303 ATGIGNTDAGFVMGTGKALLKVPPTIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRS 482 G+G +A M + VP I L G++P A DL L++ + G + Sbjct: 231 GWGVGGIEAEAGMLGQPSYFPVPEVIGAKLVGKLPNGTTATDLALKVTQVLREKGVVGKF 290 Query: 483 MEFVGSTIESLTMEERMTLCNMVIEAGGKNGVVPADETTFKY 608 +EF G I L + +R T+ NM E G G P DE Y Sbjct: 291 VEFFGPGIAELPLADRATIANMAPEYGATCGFFPVDEEALNY 332
>ACOC_CUCMA (P49608) Aconitate hydratase, cytoplasmic (EC 4.2.1.3) (Citrate| hydro-lyase) (Aconitase) Length = 898 Score = 65.5 bits (158), Expect = 1e-10 Identities = 42/144 (29%), Positives = 65/144 (45%) Frame = +3 Query: 177 RANPDYKGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFATGIGNTDAGFVMGTGKA 356 + N +Y G + G P V+ GTDSHT G G+G +A M Sbjct: 183 QVNLEYLG--RVVFNTSGLLYPDSVV-GTDSHTTMIDGLGVAGWGVGGIEAEAAMLGQPM 239 Query: 357 LLKVPPTIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMT 536 + +P + F L G++ + A DL+L + + G + +EF G +E L++ +R T Sbjct: 240 SMVLPGVVGFKLSGKLRNGVTATDLVLTVTQMLRKHGVVGKFVEFYGDGMEELSLADRAT 299 Query: 537 LCNMVIEAGGKNGVVPADETTFKY 608 + NM E G G P D T +Y Sbjct: 300 IANMSPEYGATMGFFPVDHVTLQY 323
>ACOC_CAEEL (Q23500) Probable aconitate hydratase, cytoplasmic (EC 4.2.1.3)| (Citrate hydro-lyase) (Aconitase) Length = 887 Score = 65.1 bits (157), Expect = 2e-10 Identities = 40/133 (30%), Positives = 63/133 (47%) Frame = +3 Query: 210 IALAQEGHCRPGEVLLGTDSHTCNAGAFGQFATGIGNTDAGFVMGTGKALLKVPPTIRFV 389 + + ++G P V+ GTDSHT G G+G +A VM + +P I + Sbjct: 187 VFVGKDGVLYPDSVV-GTDSHTTMIDGSGVLGWGVGGIEAEAVMLGQPISMVIPEVIGYE 245 Query: 390 LDGEMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGK 569 L G + + + DL+L I + G + +EF G+ + SL++ +R T+ NM E G Sbjct: 246 LVGTLSDTVTSTDLVLTITKNLRDLGVVGKFVEFFGTGVASLSIADRATIANMCPEYGAT 305 Query: 570 NGVVPADETTFKY 608 G P D T Y Sbjct: 306 IGFFPVDSRTIDY 318
>IREB1_CHICK (Q90875) Iron-responsive element binding protein (IRE-BP) (Iron| regulatory protein) (IRP) (Ferritin repressor protein) (Aconitate hydratase) (EC 4.2.1.3) (Citrate hydro-lyase) (Aconitase) Length = 889 Score = 65.1 bits (157), Expect = 2e-10 Identities = 37/136 (27%), Positives = 63/136 (46%) Frame = +3 Query: 201 VCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFATGIGNTDAGFVMGTGKALLKVPPTI 380 + + + Q+G+ P V+ GTDSHT G G+G +A VM + +P + Sbjct: 185 LARVVMDQDGYYYPDSVV-GTDSHTTMVDGLGVLGWGVGGIEAEAVMLGQPISMVLPEVV 243 Query: 381 RFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEA 560 + L G P + + D++L I + G + +EF G + L++ +R T+ NM E Sbjct: 244 GYKLLGNPQPLVTSTDIVLTITKHLRQVGVVGKFVEFFGPGVAQLSIADRATIANMCPEY 303 Query: 561 GGKNGVVPADETTFKY 608 G P D+ + Y Sbjct: 304 GATAAYFPVDDISIGY 319
>ACON_RICCN (Q92G90) Aconitate hydratase (EC 4.2.1.3) (Citrate hydro-lyase)| (Aconitase) Length = 878 Score = 64.7 bits (156), Expect = 2e-10 Identities = 42/156 (26%), Positives = 69/156 (44%), Gaps = 9/156 (5%) Frame = +3 Query: 168 SDFRANPDYKGVCH---------IALAQEGHCRPGEVLLGTDSHTCNAGAFGQFATGIGN 320 ++F+ P G+CH + ++G P + L+GTDSHT G+G Sbjct: 165 NNFKVVPPGTGICHQVNLEYLAKVVWHKDGTLYP-DSLVGTDSHTTMVNGLSVLGWGVGG 223 Query: 321 TDAGFVMGTGKALLKVPPTIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSMEFVGS 500 +A M + +P I L G++ A DL+L + + + +EF G Sbjct: 224 IEAEAAMLGQPLTMILPEVIGVKLTGKLTGIATATDLVLTVTEMLRKKKVVGKFVEFFGE 283 Query: 501 TIESLTMEERMTLCNMVIEAGGKNGVVPADETTFKY 608 +++L + +R T+ NM E G G P D+ T KY Sbjct: 284 GLKNLMIADRATISNMSPEYGATCGFFPIDQETIKY 319
>IREB1_RAT (Q63270) Iron-responsive element-binding protein 1 (IRE-BP 1) (Iron| regulatory protein 1) (IRP1) (Ferritin repressor protein) (Aconitate hydratase) (EC 4.2.1.3) (Citrate hydro-lyase) (Aconitase) Length = 889 Score = 64.7 bits (156), Expect = 2e-10 Identities = 38/136 (27%), Positives = 63/136 (46%) Frame = +3 Query: 201 VCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFATGIGNTDAGFVMGTGKALLKVPPTI 380 + + Q+G C + L+GTDSHT G G+G +A VM + +P I Sbjct: 185 LARVVFDQDG-CYYPDSLVGTDSHTTMIDGLGVLGWGVGGIEAEAVMLGQPISMVLPQVI 243 Query: 381 RFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEA 560 + L G+ P + + D++L I + G + +EF G + L++ +R T+ NM E Sbjct: 244 GYKLMGKPHPLVTSTDIVLTITKHLRQVGVVGKFVEFFGPGVAQLSIADRATIANMCPEY 303 Query: 561 GGKNGVVPADETTFKY 608 G P D+ + Y Sbjct: 304 GATAAFFPVDDVSIAY 319
>ACOC_ARATH (Q42560) Aconitate hydratase, cytoplasmic (EC 4.2.1.3) (Citrate| hydro-lyase) (Aconitase) Length = 898 Score = 62.8 bits (151), Expect = 8e-10 Identities = 35/119 (29%), Positives = 56/119 (47%) Frame = +3 Query: 252 LLGTDSHTCNAGAFGQFATGIGNTDAGFVMGTGKALLKVPPTIRFVLDGEMPPYLLAKDL 431 ++GTDSHT G G+G +A M + +P + F L G++ + A DL Sbjct: 205 VVGTDSHTTMIDGLGVAGWGVGGIEAEATMLGQPMSMVLPGVVGFKLTGKLRDGMTATDL 264 Query: 432 ILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGVVPADETTFKY 608 +L + + G + +EF G + L++ +R T+ NM E G G P D T +Y Sbjct: 265 VLTVTQMLRKHGVVGKFVEFHGEGMRELSLADRATIANMSPEYGATMGFFPVDHVTLQY 323
>ACOC_CUCMC (Q42669) Aconitase (EC 4.2.1.3) (Aconitate hydratase) (Citrate| hydro-lyase) (Fragment) Length = 764 Score = 61.6 bits (148), Expect = 2e-09 Identities = 41/144 (28%), Positives = 64/144 (44%) Frame = +3 Query: 177 RANPDYKGVCHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFATGIGNTDAGFVMGTGKA 356 + N +Y G + G P V+ GTDSHT G G+G +A M Sbjct: 49 QVNLEYLG--RVVFNTNGLLYPDSVV-GTDSHTTMIDGLGVAGWGVGGIEAEAAMLGQPM 105 Query: 357 LLKVPPTIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMT 536 + +P + F L G++ + A DL+L + + G + +EF G + L++ +R T Sbjct: 106 SMVLPGVVGFKLVGKLRNGVTATDLVLTVTQMLRKHGVVGKFVEFYGEGMGELSLADRAT 165 Query: 537 LCNMVIEAGGKNGVVPADETTFKY 608 + NM E G G P D T +Y Sbjct: 166 IANMSPEYGATMGFFPVDHVTLQY 189
>ACON_MYCAV (O08451) Aconitate hydratase (EC 4.2.1.3) (Citrate hydro-lyase)| (Aconitase) Length = 961 Score = 61.2 bits (147), Expect = 2e-09 Identities = 42/155 (27%), Positives = 65/155 (41%), Gaps = 8/155 (5%) Frame = +3 Query: 168 SDFRANPDYKGV--------CHIALAQEGHCRPGEVLLGTDSHTCNAGAFGQFATGIGNT 323 SDF+ P + V + + + G P + +GTDSHT G G+G Sbjct: 192 SDFKVVPPRRIVHQVNIEYLARVVMERVGVAYP-DTCVGTDSHTTMVNGLGVLGWGVGGI 250 Query: 324 DAGFVMGTGKALLKVPPTIRFVLDGEMPPYLLAKDLILQIIGEISVSGATYRSMEFVGST 503 +A M + +P + F L GE P A D++L + + G + +EF G Sbjct: 251 EAEAAMLGQPVSMLIPRVVGFKLTGEDPAPGAATDVVLTVTEICAKHGVVGKFVEFYGEG 310 Query: 504 IESLTMEERMTLCNMVIEAGGKNGVVPADETTFKY 608 + + + R TL NM E G + P D+ T Y Sbjct: 311 VAEVPLANRATLGNMSPEFGSTAAIFPIDQETIDY 345 Database: uniprot_sprot.fasta Posted date: May 25, 2006 5:36 PM Number of letters in database: 80,573,946 Number of sequences in database: 219,361 Lambda K H 0.318 0.135 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 84,292,793 Number of Sequences: 219361 Number of extensions: 1822360 Number of successful extensions: 4865 Number of sequences better than 10.0: 267 Number of HSP's better than 10.0 without gapping: 4677 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 4843 length of database: 80,573,946 effective HSP length: 107 effective length of database: 57,102,319 effective search space used: 5424720305 frameshift window, decay const: 50, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
