ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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| Clone Name | basdn22 |
|---|---|
| Clone Library Name | barley_pub |
>C1TM_YEAST (P09440) C-1-tetrahydrofolate synthase, mitochondrial precursor| (C1-THF synthase) [Includes: Methylenetetrahydrofolate dehydrogenase (EC 1.5.1.5); Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9); Formyltetrahydrofolate synthetase (EC 6.3. Length = 975 Score = 206 bits (524), Expect = 4e-53 Identities = 98/188 (52%), Positives = 133/188 (70%) Frame = +3 Query: 3 LVAEVHRLNADPAVHGILVQLPLPKHINEEIILNQISIEKDVDGFHPLNIGKLAMKGRNP 182 L+ ++ +N D ++HG+L+QLPLP+H++E I N + +KDVDGFH N G+LA KG P Sbjct: 112 LLKKISDINDDDSIHGLLIQLPLPRHLDETTITNAVDFKKDVDGFHRYNAGELAKKGGKP 171 Query: 183 LFLPCTPKGCMELLSRSGVTVKGKHAVVVGRSNIVGLPVSLLLLKADATVSIVHSRTPNP 362 F+PCTP GCM+LL + V + GK+AVV+GRS+IVG P++ LL A+ATV++ HS T N Sbjct: 172 YFIPCTPYGCMKLLEEAHVKLDGKNAVVLGRSSIVGNPIASLLKNANATVTVCHSHTRNI 231 Query: 363 ETIVCQADIVIAAAGQAMMIKGDWIKPGAAVIDVGTNSIDDPTRKSGYRLVGDVDFAEAS 542 +V QADIVIAA G +K DWIK GA VIDVG N + D ++KSG +LVGDVDF Sbjct: 232 AEVVSQADIVIAACGIPQYVKSDWIKEGAVVIDVGINYVPDISKKSGQKLVGDVDFDSVK 291 Query: 543 KVAGHLTP 566 + ++TP Sbjct: 292 EKTSYITP 299
>C1TC_YEAST (P07245) C-1-tetrahydrofolate synthase, cytoplasmic (C1-THF| synthase) [Includes: Methylenetetrahydrofolate dehydrogenase (EC 1.5.1.5); Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9); Formyltetrahydrofolate synthetase (EC 6.3.4.3)] Length = 946 Score = 195 bits (495), Expect = 9e-50 Identities = 97/192 (50%), Positives = 133/192 (69%), Gaps = 8/192 (4%) Frame = +3 Query: 15 VHRLNADPAVHGILVQLPLPKHINEEIILNQISIEKDVDGFHPLNIGKLAMKGRNPLFLP 194 V +LN DP HGI+VQLPLP H++E+ I +++ EKDVDGF P NIG+L K +P FLP Sbjct: 84 VDQLNEDPHTHGIIVQLPLPAHLDEDRITSRVLAEKDVDGFGPTNIGELNKKNGHPFFLP 143 Query: 195 CTPKGCMELLSRSGVTVKGKHAVVVGRSNIVGLPVSLLLLKADATVSIVHSRTPNPETIV 374 CTPKG +ELL ++ VT++G +VV+GRS+IVG PV+ LL ++TV+I HS+T + + + Sbjct: 144 CTPKGIIELLHKANVTIEGSRSVVIGRSDIVGSPVAELLKSLNSTVTITHSKTRDIASYL 203 Query: 375 CQADIVIAAAGQAMMIKGDWIKP--------GAAVIDVGTNSIDDPTRKSGYRLVGDVDF 530 ADIV+ A GQ +KG+W KP VIDVGTN + DP++KSG++ VGDV+F Sbjct: 204 HDADIVVVAIGQPEFVKGEWFKPRDGTSSDKKTVVIDVGTNYVADPSKKSGFKCVGDVEF 263 Query: 531 AEASKVAGHLTP 566 EA K +TP Sbjct: 264 NEAIKYVHLITP 275
>C1TC_DROME (O96553) C-1-tetrahydrofolate synthase, cytoplasmic (C1-THF| synthase) [Includes: Methylenetetrahydrofolate dehydrogenase (EC 1.5.1.5); Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9); Formyltetrahydrofolate synthetase (EC 6.3.4.3)] Length = 968 Score = 192 bits (487), Expect = 7e-49 Identities = 103/190 (54%), Positives = 132/190 (69%), Gaps = 2/190 (1%) Frame = +3 Query: 3 LVAEVHRLNADPAVHGILVQLPLP--KHINEEIILNQISIEKDVDGFHPLNIGKLAMKGR 176 L+ +++ LN DP VHGI+VQ+PL I+ I + +S EKDVDG H +N G+LA+ G Sbjct: 115 LLDKINDLNEDPRVHGIIVQMPLDCDTPIDSHRITDAVSPEKDVDGLHTVNEGRLAI-GD 173 Query: 177 NPLFLPCTPKGCMELLSRSGVTVKGKHAVVVGRSNIVGLPVSLLLLKADATVSIVHSRTP 356 FLPCTP GC+EL+ RSGV + G AVV+GRS IVG P + LL A+ATV++ HS+T Sbjct: 174 LGGFLPCTPWGCLELIRRSGVEIAGARAVVLGRSKIVGTPAAELLKWANATVTVCHSKTR 233 Query: 357 NPETIVCQADIVIAAAGQAMMIKGDWIKPGAAVIDVGTNSIDDPTRKSGYRLVGDVDFAE 536 N E I ADI++ G A M+KG WIKPGA VID G N D ++ SG +LVGDVD+AE Sbjct: 234 NLEEITRSADILVVGIGVAEMVKGSWIKPGAVVIDCGINVKPDASKASGSKLVGDVDYAE 293 Query: 537 ASKVAGHLTP 566 A +VAGHLTP Sbjct: 294 ALQVAGHLTP 303
>C1TC_SPOFR (Q27772) C-1-tetrahydrofolate synthase, cytoplasmic (C1-THF| synthase) [Includes: Methylenetetrahydrofolate dehydrogenase (EC 1.5.1.5); Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9); Formyltetrahydrofolate synthetase (EC 6.3.4.3)] Length = 933 Score = 189 bits (480), Expect = 5e-48 Identities = 98/190 (51%), Positives = 130/190 (68%), Gaps = 2/190 (1%) Frame = +3 Query: 3 LVAEVHRLNADPAVHGILVQLPLPK--HINEEIILNQISIEKDVDGFHPLNIGKLAMKGR 176 L+A + LN P VHGI+VQ+PL I+ I + +S +KDVDG + +N G++ + G Sbjct: 80 LLANITSLNESPYVHGIIVQMPLDSVHPIDSHAITDAVSPDKDVDGLNTINEGRVRV-GD 138 Query: 177 NPLFLPCTPKGCMELLSRSGVTVKGKHAVVVGRSNIVGLPVSLLLLKADATVSIVHSRTP 356 F+PCTP GC+EL+ R+GVT+ GK+ VV+GRS IVG PVS LL ATV++ HS+T Sbjct: 139 LSGFIPCTPAGCVELIKRTGVTIAGKNVVVLGRSRIVGTPVSELLKWEHATVTVCHSKTK 198 Query: 357 NPETIVCQADIVIAAAGQAMMIKGDWIKPGAAVIDVGTNSIDDPTRKSGYRLVGDVDFAE 536 N I ADI++ A G+ M++G WIKPGA VID G N I DPT+KSG RLVGDV + E Sbjct: 199 NLSEITKTADILVVAIGRGEMVRGSWIKPGAVVIDCGINPISDPTKKSGQRLVGDVAYEE 258 Query: 537 ASKVAGHLTP 566 A +VA H+TP Sbjct: 259 AVQVASHVTP 268
>C1TC_MOUSE (Q922D8) C-1-tetrahydrofolate synthase, cytoplasmic (C1-THF| synthase) [Includes: Methylenetetrahydrofolate dehydrogenase (EC 1.5.1.5); Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9); Formyltetrahydrofolate synthetase (EC 6.3.4.3)] Length = 934 Score = 186 bits (472), Expect = 4e-47 Identities = 94/183 (51%), Positives = 125/183 (68%), Gaps = 2/183 (1%) Frame = +3 Query: 24 LNADPAVHGILVQLPLPKH--INEEIILNQISIEKDVDGFHPLNIGKLAMKGRNPLFLPC 197 LN D +VHG +VQLPL IN E ++N I+ EKDVDG ++ GKLA N F+PC Sbjct: 87 LNEDASVHGFIVQLPLDSENSINTEAVINAIAPEKDVDGLTSVSAGKLARGDLNDCFIPC 146 Query: 198 TPKGCMELLSRSGVTVKGKHAVVVGRSNIVGLPVSLLLLKADATVSIVHSRTPNPETIVC 377 TPKGC+EL+ +GV + G+HAVVVGRS IVG P+ LLL +ATV+ HS+T N + V Sbjct: 147 TPKGCLELIKEAGVQIAGRHAVVVGRSKIVGAPMHDLLLWNNATVTTCHSKTANLDKEVN 206 Query: 378 QADIVIAAAGQAMMIKGDWIKPGAAVIDVGTNSIDDPTRKSGYRLVGDVDFAEASKVAGH 557 + DI++ A GQ M+KG+WIKPGA VID G N + D T+ +G ++VGDV + EA + A Sbjct: 207 KGDILVVATGQPEMVKGEWIKPGAVVIDCGINYVPDDTKPNGRKVVGDVAYDEAKERASF 266 Query: 558 LTP 566 +TP Sbjct: 267 ITP 269
>FOLD_HAEIN (P44313) FolD bifunctional protein [Includes:| Methylenetetrahydrofolate dehydrogenase (EC 1.5.1.5); Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9)] Length = 281 Score = 184 bits (467), Expect = 2e-46 Identities = 98/188 (52%), Positives = 127/188 (67%) Frame = +3 Query: 3 LVAEVHRLNADPAVHGILVQLPLPKHINEEIILNQISIEKDVDGFHPLNIGKLAMKGRNP 182 L+A + +LNAD + GILVQLPLPK IN E I+ +I +KDVDGFHP N+G+L R P Sbjct: 78 LLAIIDQLNADKNIDGILVQLPLPKQINAEAIIERIDPKKDVDGFHPYNVGRLCQ--RIP 135 Query: 183 LFLPCTPKGCMELLSRSGVTVKGKHAVVVGRSNIVGLPVSLLLLKADATVSIVHSRTPNP 362 CTP G M+LL +G+ + GKHAV+VG SNIVG P+SL LL A ATV++ H T N Sbjct: 136 TLRACTPYGVMKLLETTGIDLHGKHAVIVGASNIVGRPMSLELLLAGATVTVTHRFTKNL 195 Query: 363 ETIVCQADIVIAAAGQAMMIKGDWIKPGAAVIDVGTNSIDDPTRKSGYRLVGDVDFAEAS 542 E V QADI++ A G+ +I GDWIK A VIDVG N +D +LVGDV+F +A+ Sbjct: 196 ENHVRQADILVVAVGKPNLISGDWIKESAVVIDVGINRVDG-------KLVGDVEFDKAA 248 Query: 543 KVAGHLTP 566 + A ++TP Sbjct: 249 EKAAYITP 256
>C1TC_RAT (P27653) C-1-tetrahydrofolate synthase, cytoplasmic (C1-THF| synthase) [Includes: Methylenetetrahydrofolate dehydrogenase (EC 1.5.1.5); Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9); Formyltetrahydrofolate synthetase (EC 6.3.4.3)] Length = 934 Score = 184 bits (467), Expect = 2e-46 Identities = 93/183 (50%), Positives = 123/183 (67%), Gaps = 2/183 (1%) Frame = +3 Query: 24 LNADPAVHGILVQLPLPKH--INEEIILNQISIEKDVDGFHPLNIGKLAMKGRNPLFLPC 197 LN D VHG +VQLPL IN E ++N I+ EKDVDG +N GKLA F+PC Sbjct: 87 LNEDATVHGFIVQLPLDSENSINTEAVINAIAPEKDVDGLTSINAGKLARGDLKDCFIPC 146 Query: 198 TPKGCMELLSRSGVTVKGKHAVVVGRSNIVGLPVSLLLLKADATVSIVHSRTPNPETIVC 377 TPKGC+EL+ +GV + G+HAVVVGRS IVG P+ LLL +ATV+ HS+T + + V Sbjct: 147 TPKGCLELIKETGVQIAGRHAVVVGRSKIVGAPMHDLLLWNNATVTTCHSKTADLDKEVN 206 Query: 378 QADIVIAAAGQAMMIKGDWIKPGAAVIDVGTNSIDDPTRKSGYRLVGDVDFAEASKVAGH 557 + DI++ A GQ M+KG+WIKPGA VID G N + D T+ +G ++VGDV + EA + A Sbjct: 207 KGDILVVATGQPEMVKGEWIKPGAVVIDCGINYVPDDTKPNGRKVVGDVAYDEAKEKASF 266 Query: 558 LTP 566 +TP Sbjct: 267 ITP 269
>C1TC_HUMAN (P11586) C-1-tetrahydrofolate synthase, cytoplasmic (C1-THF| synthase) [Includes: Methylenetetrahydrofolate dehydrogenase (EC 1.5.1.5); Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9); Formyltetrahydrofolate synthetase (EC 6.3.4.3)] Length = 934 Score = 182 bits (462), Expect = 6e-46 Identities = 93/183 (50%), Positives = 123/183 (67%), Gaps = 2/183 (1%) Frame = +3 Query: 24 LNADPAVHGILVQLPLPKH--INEEIILNQISIEKDVDGFHPLNIGKLAMKGRNPLFLPC 197 LN D VHG LVQLPL IN E ++N I+ EKDVDG +N G+LA N F+PC Sbjct: 87 LNEDSTVHGFLVQLPLDSENSINTEEVINAIAPEKDVDGLTSINAGRLARGDLNDCFIPC 146 Query: 198 TPKGCMELLSRSGVTVKGKHAVVVGRSNIVGLPVSLLLLKADATVSIVHSRTPNPETIVC 377 TPKGC+EL+ +GV + G+HAVVVGRS IVG P+ LLL +ATV+ HS+T + + V Sbjct: 147 TPKGCLELIKETGVPIAGRHAVVVGRSKIVGAPMHDLLLWNNATVTTCHSKTAHLDEEVN 206 Query: 378 QADIVIAAAGQAMMIKGDWIKPGAAVIDVGTNSIDDPTRKSGYRLVGDVDFAEASKVAGH 557 + DI++ A GQ M+KG+WIKPGA VID G N + D + +G ++VGDV + EA + A Sbjct: 207 KGDILVVATGQPEMVKGEWIKPGAIVIDCGINYVPDDKKPNGRKVVGDVAYDEAKERASF 266 Query: 558 LTP 566 +TP Sbjct: 267 ITP 269
>FOLD_BACSU (P54382) FolD bifunctional protein [Includes:| Methylenetetrahydrofolate dehydrogenase (EC 1.5.1.5); Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9)] Length = 283 Score = 177 bits (448), Expect = 2e-44 Identities = 93/188 (49%), Positives = 124/188 (65%) Frame = +3 Query: 3 LVAEVHRLNADPAVHGILVQLPLPKHINEEIILNQISIEKDVDGFHPLNIGKLAMKGRNP 182 L++ + + N DP HGILVQLPLP HI+E+ ++ +IS +KDVDGFHPLN+GK+ + Sbjct: 78 LLSIIDQYNQDPEFHGILVQLPLPDHISEKAVIERISPDKDVDGFHPLNVGKMLLG--ED 135 Query: 183 LFLPCTPKGCMELLSRSGVTVKGKHAVVVGRSNIVGLPVSLLLLKADATVSIVHSRTPNP 362 FLPCTP G +ELL ++ + + GK VVVGRSNIVG PV LLL +ATV+ HSRT N Sbjct: 136 TFLPCTPHGIVELLKKTNIDLSGKEVVVVGRSNIVGKPVGQLLLNENATVTYCHSRTENI 195 Query: 363 ETIVCQADIVIAAAGQAMMIKGDWIKPGAAVIDVGTNSIDDPTRKSGYRLVGDVDFAEAS 542 +ADI++ A G+A I D IK GA VIDVG N +++ +L GDV+F A Sbjct: 196 TEHTKKADILVVAVGRANFISADQIKEGAVVIDVGVNRLENG------KLCGDVEFEGAK 249 Query: 543 KVAGHLTP 566 + A +TP Sbjct: 250 EKASFITP 257
>FOLD_CHLPN (Q9Z8K3) FolD bifunctional protein [Includes:| Methylenetetrahydrofolate dehydrogenase (EC 1.5.1.5); Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9)] Length = 286 Score = 172 bits (436), Expect = 6e-43 Identities = 88/188 (46%), Positives = 125/188 (66%), Gaps = 4/188 (2%) Frame = +3 Query: 15 VHRLNADPAVHGILVQLPLPKHINEEIILNQISIEKDVDGFHPLNIGKLAMKGRNPLFLP 194 + RLN DP++HGILVQLPLPKH++ E+IL IS +KDVDG HP+N+GKL + G LP Sbjct: 76 IERLNQDPSIHGILVQLPLPKHLDSEVILQAISPDKDVDGLHPVNMGKLLL-GNFDGLLP 134 Query: 195 CTPKGCMELLSRSGVTVKGKHAVVVGRSNIVGLPVSLLLL----KADATVSIVHSRTPNP 362 CTP G +ELL+ + ++G+HA +VGRSNIVG P++ L++ + + TV+++HS++ N Sbjct: 135 CTPAGIIELLNYYEIPLRGRHAAIVGRSNIVGKPLAALMMQKHPQTNCTVTVLHSQSENL 194 Query: 363 ETIVCQADIVIAAAGQAMMIKGDWIKPGAAVIDVGTNSIDDPTRKSGYRLVGDVDFAEAS 542 I+ ADI+IAA G + IK + P A ++DVGT + K GY L+GDVDF Sbjct: 195 PEILKTADIIIAALGAPLFIKETMVAPHAVIVDVGTTRVPADNAK-GYTLLGDVDFNNVV 253 Query: 543 KVAGHLTP 566 +TP Sbjct: 254 TKCAAITP 261
>FOLD_STRTR (P96050) FolD bifunctional protein [Includes:| Methylenetetrahydrofolate dehydrogenase (EC 1.5.1.5); Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9)] Length = 284 Score = 168 bits (426), Expect = 9e-42 Identities = 90/188 (47%), Positives = 122/188 (64%) Frame = +3 Query: 3 LVAEVHRLNADPAVHGILVQLPLPKHINEEIILNQISIEKDVDGFHPLNIGKLAMKGRNP 182 L+ + + N +P HGILVQLPLP HINE IL I +KDVDGFHP+N G L GR P Sbjct: 78 LIEVIEKYNQNPLFHGILVQLPLPNHINEMRILLAIDPKKDVDGFHPMNTGNL-WNGR-P 135 Query: 183 LFLPCTPKGCMELLSRSGVTVKGKHAVVVGRSNIVGLPVSLLLLKADATVSIVHSRTPNP 362 +PCTP G ME+L V ++GK AV++GRSNIVG P++ LLL+ +ATV++ HSRTP+ Sbjct: 136 QMVPCTPAGIMEILREYNVELEGKTAVIIGRSNIVGKPMAQLLLEKNATVTLTHSRTPHL 195 Query: 363 ETIVCQADIVIAAAGQAMMIKGDWIKPGAAVIDVGTNSIDDPTRKSGYRLVGDVDFAEAS 542 + +AD++I A G+A + +++K GA VIDVG N R +L GDVDF + Sbjct: 196 AKVCNKADVLIVAIGRAKFVTEEFVKEGAVVIDVGIN------RDEEGKLCGDVDFDQVK 249 Query: 543 KVAGHLTP 566 + +TP Sbjct: 250 EKVSMITP 257
>FOLD_BUCBP (Q89A92) FolD bifunctional protein [Includes:| Methylenetetrahydrofolate dehydrogenase (EC 1.5.1.5); Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9)] Length = 287 Score = 163 bits (413), Expect = 3e-40 Identities = 87/184 (47%), Positives = 117/184 (63%) Frame = +3 Query: 15 VHRLNADPAVHGILVQLPLPKHINEEIILNQISIEKDVDGFHPLNIGKLAMKGRNPLFLP 194 +++LN D + GILVQLP+P +IN + + + I KDVDGFHP NIG L K +P P Sbjct: 83 IYKLNYDTTIDGILVQLPIPPNINNQKLFSSIIPTKDVDGFHPYNIGSLCQK--SPYLRP 140 Query: 195 CTPKGCMELLSRSGVTVKGKHAVVVGRSNIVGLPVSLLLLKADATVSIVHSRTPNPETIV 374 CTP G + +L + ++G HAVV+G SNIVG P+S+ LL A T +I H T N + V Sbjct: 141 CTPFGIITMLKHYKIKIRGLHAVVIGASNIVGRPMSMELLLAGCTTTITHRFTKNLKHYV 200 Query: 375 CQADIVIAAAGQAMMIKGDWIKPGAAVIDVGTNSIDDPTRKSGYRLVGDVDFAEASKVAG 554 QAD+++ A G A +KG WIK GA VIDVG N + K+G +VGDVDF A K + Sbjct: 201 KQADLIVIAIGHAHFLKGTWIKKGAIVIDVGINRL-----KNG-EIVGDVDFKTAYKKSS 254 Query: 555 HLTP 566 ++TP Sbjct: 255 YITP 258
>FOLD_HELPY (P56467) FolD bifunctional protein [Includes:| Methylenetetrahydrofolate dehydrogenase (EC 1.5.1.5); Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9)] Length = 290 Score = 162 bits (411), Expect = 5e-40 Identities = 85/188 (45%), Positives = 116/188 (61%) Frame = +3 Query: 3 LVAEVHRLNADPAVHGILVQLPLPKHINEEIILNQISIEKDVDGFHPLNIGKLAMKGRNP 182 L++ + N D + G+LVQLPLP+HI+ ++IL I KDVDGFHPLNIGKL + + Sbjct: 82 LLSLIKDYNTDQNISGVLVQLPLPRHIDTKMILEAIDPNKDVDGFHPLNIGKLCTQKES- 140 Query: 183 LFLPCTPKGCMELLSRSGVTVKGKHAVVVGRSNIVGLPVSLLLLKADATVSIVHSRTPNP 362 FLP TP G M LL + +KGK ++G SNI+G P+S+L+L A A+VS+ H T + Sbjct: 141 -FLPATPMGVMRLLEHYHIEIKGKDVAIIGASNIIGKPLSMLMLNAGASVSVCHILTKDI 199 Query: 363 ETIVCQADIVIAAAGQAMMIKGDWIKPGAAVIDVGTNSIDDPTRKSGYRLVGDVDFAEAS 542 ADIV G+ +IK +K GA V+D+G N ++D R+VGDVDF Sbjct: 200 SFYTQNADIVCVGVGKPDLIKASMLKKGAVVVDIGINHLNDG------RIVGDVDFNNVQ 253 Query: 543 KVAGHLTP 566 KVAG +TP Sbjct: 254 KVAGFITP 261
>FOLD_CHLMU (Q9PKW1) FolD bifunctional protein [Includes:| Methylenetetrahydrofolate dehydrogenase (EC 1.5.1.5); Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9)] Length = 287 Score = 161 bits (408), Expect = 1e-39 Identities = 85/194 (43%), Positives = 126/194 (64%), Gaps = 6/194 (3%) Frame = +3 Query: 3 LVAEVHRLNADPAVHGILVQLPLPKHINEEIILNQISIEKDVDGFHPLNIGKLAMKGRNP 182 +++ +H LN D +HG+LVQLPLPKH++ + IL+ IS KDVDG HP+N+GKL + G Sbjct: 72 ILSLIHELNCDENIHGVLVQLPLPKHLDTQTILSSISPNKDVDGLHPVNMGKLLL-GETD 130 Query: 183 LFLPCTPKGCMELLSRSGVTVKGKHAVVVGRSNIVGLPVSLLLLK----ADATVSIVHSR 350 F+PCTP G +EL + + GKH V++GRSNIVG P+S LL++ +A+V+++HS+ Sbjct: 131 GFIPCTPSGIVELFKYYEIPLYGKHVVILGRSNIVGKPLSALLMQKHADTNASVTVLHSQ 190 Query: 351 TPNPETIVCQADIVIAAAGQAMMIKGDWIKPGAAVIDVGTNSI--DDPTRKSGYRLVGDV 524 + + + I ADI+++A G + + + I VIDVGT+ + D+P GY LVGDV Sbjct: 191 SEHLKEITKTADILVSAIGVPLFVTKEMISEKCIVIDVGTSRVPADNP---KGYSLVGDV 247 Query: 525 DFAEASKVAGHLTP 566 DF V +TP Sbjct: 248 DFNNVVPVCQAITP 261
>FOLD_HELPJ (Q9ZLQ4) FolD bifunctional protein [Includes:| Methylenetetrahydrofolate dehydrogenase (EC 1.5.1.5); Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9)] Length = 290 Score = 161 bits (407), Expect = 1e-39 Identities = 85/188 (45%), Positives = 116/188 (61%) Frame = +3 Query: 3 LVAEVHRLNADPAVHGILVQLPLPKHINEEIILNQISIEKDVDGFHPLNIGKLAMKGRNP 182 L++ + N D + GILVQLPLP+ I+ ++IL I KDVDGFHPLNIGKL + + Sbjct: 82 LLSLIKDYNTDQNISGILVQLPLPRSIDTKMILEAIDPNKDVDGFHPLNIGKLCTQKES- 140 Query: 183 LFLPCTPKGCMELLSRSGVTVKGKHAVVVGRSNIVGLPVSLLLLKADATVSIVHSRTPNP 362 FLP TP G M LL + +KGK ++G SNI+G P+S+L+L A A+VS+ H T + Sbjct: 141 -FLPATPMGVMRLLEHYHIEIKGKDVAIIGASNIIGKPLSMLMLNAGASVSVCHILTKDI 199 Query: 363 ETIVCQADIVIAAAGQAMMIKGDWIKPGAAVIDVGTNSIDDPTRKSGYRLVGDVDFAEAS 542 ADIV G+ +IK +K GA V+D+G N ++D R+VGDVDF A Sbjct: 200 SFYTKNADIVCVGVGKPDLIKASMLKKGAVVVDIGINHLNDG------RIVGDVDFINAQ 253 Query: 543 KVAGHLTP 566 K+AG +TP Sbjct: 254 KIAGFITP 261
>FOLD_PHOPO (P51696) FolD bifunctional protein (PPDC) [Includes:| Methylenetetrahydrofolate dehydrogenase (EC 1.5.1.5); Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9)] Length = 285 Score = 160 bits (405), Expect = 2e-39 Identities = 89/184 (48%), Positives = 117/184 (63%) Frame = +3 Query: 15 VHRLNADPAVHGILVQLPLPKHINEEIILNQISIEKDVDGFHPLNIGKLAMKGRNPLFLP 194 + LN DP + GILVQLPLP ++ IL +I EKDVDGFHP N+G+L+ R P Sbjct: 83 IDELNQDPTMDGILVQLPLPAGMDCTRILERIDPEKDVDGFHPYNVGRLSQ--RIPKLRS 140 Query: 195 CTPKGCMELLSRSGVTVKGKHAVVVGRSNIVGLPVSLLLLKADATVSIVHSRTPNPETIV 374 CTPKG + LL R + V+GKHAV+VG SNIVG P++L LL A AT + H T + E + Sbjct: 141 CTPKGIITLLERYNIEVRGKHAVIVGASNIVGRPMTLELLLAGATTTTCHRFTQDLEGHI 200 Query: 375 CQADIVIAAAGQAMMIKGDWIKPGAAVIDVGTNSIDDPTRKSGYRLVGDVDFAEASKVAG 554 QADI++ A G+ I G WIK GA VIDVG N +++ +L GDV+F A + A Sbjct: 201 RQADILVVAVGKPNFIPGGWIKEGATVIDVGINRLENG------KLCGDVEFDVACQRAK 254 Query: 555 HLTP 566 ++TP Sbjct: 255 YITP 258
>MTDC_MOUSE (P18155) Bifunctional methylenetetrahydrofolate| dehydrogenase/cyclohydrolase, mitochondrial precursor [Includes: NAD-dependent methylenetetrahydrofolate dehydrogenase (EC 1.5.1.15); Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9)] Length = 350 Score = 159 bits (403), Expect = 4e-39 Identities = 92/200 (46%), Positives = 125/200 (62%), Gaps = 12/200 (6%) Frame = +3 Query: 3 LVAEVHRLNADPAVHGILVQLPLPKHINEEIILNQISIEKDVDGFHPLNIGKLAMKGRNP 182 L+ + +LN D V G+LVQLPLP+HI+E + N +S +KDVDGFH +N+G++ + + Sbjct: 113 LLNSIRKLNNDENVDGLLVQLPLPEHIDERKVCNAVSPDKDVDGFHVINVGRMCLDQYS- 171 Query: 183 LFLPCTPKGCMELLSRSGVTVKGKHAVVVGRSNIVGLPVSLLLLK--------ADATVSI 338 LP TP G E++ R+G+ GK+ VV GRS VG+P+++LL DATV+I Sbjct: 172 -MLPATPWGVWEIIKRTGIPTLGKNVVVAGRSKNVGMPIAMLLHTDGAHERPGGDATVTI 230 Query: 339 VHSRTPNPE----TIVCQADIVIAAAGQAMMIKGDWIKPGAAVIDVGTNSIDDPTRKSGY 506 H TP + TI+ ADIVI+AAG +I D IK GAAVIDVG N + DP Sbjct: 231 SHRYTPKEQLKKHTIL--ADIVISAAGIPNLITADMIKEGAAVIDVGINRVQDPVTAKP- 287 Query: 507 RLVGDVDFAEASKVAGHLTP 566 +LVGDVDF K AG++TP Sbjct: 288 KLVGDVDFEGVKKKAGYITP 307
>FOLD_CHLTR (O84081) FolD bifunctional protein [Includes:| Methylenetetrahydrofolate dehydrogenase (EC 1.5.1.5); Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9)] Length = 287 Score = 159 bits (401), Expect = 7e-39 Identities = 84/192 (43%), Positives = 125/192 (65%), Gaps = 4/192 (2%) Frame = +3 Query: 3 LVAEVHRLNADPAVHGILVQLPLPKHINEEIILNQISIEKDVDGFHPLNIGKLAMKGRNP 182 ++A +H+LN D +HGILVQLPLPKH++ + IL+ I+ +KDVDG HP+N+GKL + G Sbjct: 72 ILALIHQLNNDENIHGILVQLPLPKHLDAQAILSTITPDKDVDGLHPVNVGKLLL-GETD 130 Query: 183 LFLPCTPKGCMELLSRSGVTVKGKHAVVVGRSNIVGLPVSLLLLK----ADATVSIVHSR 350 F+PCTP G +EL + + GKH V++GRSNIVG P++ LL++ +A+V+++HS+ Sbjct: 131 GFIPCTPAGIVELCKYYEIPLHGKHVVILGRSNIVGKPLAALLMQRHADTNASVTLLHSQ 190 Query: 351 TPNPETIVCQADIVIAAAGQAMMIKGDWIKPGAAVIDVGTNSIDDPTRKSGYRLVGDVDF 530 + + I ADI+I+A G + + + I ++DVGT+ I K GY LVGDVDF Sbjct: 191 SEHLTEITRTADILISAIGVPLFVNKEMIAEKTVIMDVGTSRIPAANPK-GYILVGDVDF 249 Query: 531 AEASKVAGHLTP 566 V +TP Sbjct: 250 NNVVPVCRAITP 261
>MTDC_DROME (Q04448) Bifunctional methylenetetrahydrofolate| dehydrogenase/cyclohydrolase, mitochondrial precursor (DNMDMC) [Includes: NAD-dependent methylenetetrahydrofolate dehydrogenase (EC 1.5.1.15); Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9) Length = 309 Score = 159 bits (401), Expect = 7e-39 Identities = 93/191 (48%), Positives = 120/191 (62%), Gaps = 10/191 (5%) Frame = +3 Query: 24 LNADPAVHGILVQLPLPKHINEEIILNQISIEKDVDGFHPLNIGKLAMKGRNPLFLPCTP 203 LN DP V GILVQLP+P+HINE I N + ++KDVDGF+ +NIG+ A+ +P TP Sbjct: 91 LNKDPQVTGILVQLPVPEHINERTICNAVDVDKDVDGFNEVNIGRTALD--MEANIPATP 148 Query: 204 KGCMELLSRSGVTVKGKHAVVVGRSNIVGLPVSLLL-------LKA-DATVSIVHSRTPN 359 G LL + G++AVVVGRS V LP+++LL KA DATV+I H TP Sbjct: 149 LGVKRLLEHMKIETLGRNAVVVGRSKNVSLPMAILLHADGKYATKAMDATVTICHRYTPP 208 Query: 360 PETI--VCQADIVIAAAGQAMMIKGDWIKPGAAVIDVGTNSIDDPTRKSGYRLVGDVDFA 533 E QADI++ A G+ +I D +KPGA VIDVG N I D + ++LVGDVDF Sbjct: 209 KELARHCRQADIIVVAVGKPGLITKDMVKPGACVIDVGINRIKDES-TGQFKLVGDVDFE 267 Query: 534 EASKVAGHLTP 566 E +VAGH+TP Sbjct: 268 EVRQVAGHITP 278
>FOLD_RICCN (Q92HY4) FolD bifunctional protein [Includes:| Methylenetetrahydrofolate dehydrogenase (EC 1.5.1.5); Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9)] Length = 288 Score = 158 bits (400), Expect = 9e-39 Identities = 80/188 (42%), Positives = 120/188 (63%) Frame = +3 Query: 3 LVAEVHRLNADPAVHGILVQLPLPKHINEEIILNQISIEKDVDGFHPLNIGKLAMKGRNP 182 L+++++ LN D + GI+VQLPLP I++ IL+ +S KD+DGFHPLN+G L G + Sbjct: 78 LISKINELNLDNEISGIIVQLPLPSSIDKNKILSAVSPSKDIDGFHPLNVGYLH-SGISQ 136 Query: 183 LFLPCTPKGCMELLSRSGVTVKGKHAVVVGRSNIVGLPVSLLLLKADATVSIVHSRTPNP 362 F+PCT GC+ + + + GK+ V++GRSNIVG P+S LLLK + +V+I HS+T N Sbjct: 137 GFIPCTALGCLAAIKKYEPNLTGKNVVIIGRSNIVGKPLSALLLKENCSVTICHSKTHNL 196 Query: 363 ETIVCQADIVIAAAGQAMMIKGDWIKPGAAVIDVGTNSIDDPTRKSGYRLVGDVDFAEAS 542 +I +ADIV+AA G + + ++ P + VIDVG N I S +++GDVDF Sbjct: 197 RSITSKADIVVAAIGSPLKLTAEYFNPKSIVIDVGINRI------SSNKIIGDVDFENVQ 250 Query: 543 KVAGHLTP 566 ++TP Sbjct: 251 SKVQYITP 258
>FOLD_ECOLI (P24186) FolD bifunctional protein [Includes:| Methylenetetrahydrofolate dehydrogenase (EC 1.5.1.5); Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9)] Length = 287 Score = 157 bits (397), Expect = 2e-38 Identities = 87/188 (46%), Positives = 117/188 (62%) Frame = +3 Query: 3 LVAEVHRLNADPAVHGILVQLPLPKHINEEIILNQISIEKDVDGFHPLNIGKLAMKGRNP 182 L+ + LNAD + GILVQLPLP I+ +L +I +KDVDGFHP N+G+L R P Sbjct: 78 LLELIDTLNADNTIDGILVQLPLPAGIDNVKVLERIHPDKDVDGFHPYNVGRLCQ--RAP 135 Query: 183 LFLPCTPKGCMELLSRSGVTVKGKHAVVVGRSNIVGLPVSLLLLKADATVSIVHSRTPNP 362 PCTP+G + LL R + G +AVV+G SNIVG P+S+ LL A T ++ H T N Sbjct: 136 RLRPCTPRGIVTLLERYNIDTFGLNAVVIGASNIVGRPMSMELLLAGCTTTVTHRFTKNL 195 Query: 363 ETIVCQADIVIAAAGQAMMIKGDWIKPGAAVIDVGTNSIDDPTRKSGYRLVGDVDFAEAS 542 V AD++I A G+ I GDWIK GA VIDVG N +++ ++VGDV F +A+ Sbjct: 196 RHHVENADLLIVAVGKPGFIPGDWIKEGAIVIDVGINRLENG------KVVGDVVFEDAA 249 Query: 543 KVAGHLTP 566 K A ++TP Sbjct: 250 KRASYITP 257
>MTDC_HUMAN (P13995) Bifunctional methylenetetrahydrofolate| dehydrogenase/cyclohydrolase, mitochondrial precursor [Includes: NAD-dependent methylenetetrahydrofolate dehydrogenase (EC 1.5.1.15); Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9)] Length = 344 Score = 157 bits (396), Expect = 3e-38 Identities = 91/196 (46%), Positives = 124/196 (63%), Gaps = 12/196 (6%) Frame = +3 Query: 15 VHRLNADPAVHGILVQLPLPKHINEEIILNQISIEKDVDGFHPLNIGKLAMKGRNPLFLP 194 +++LN D V G+LVQLPLP+HI+E I N +S +KDVDGFH +N+G++ + + LP Sbjct: 111 INKLNNDDNVDGLLVQLPLPEHIDERRICNAVSPDKDVDGFHVINVGRMCLDQYS--MLP 168 Query: 195 CTPKGCMELLSRSGVTVKGKHAVVVGRSNIVGLPVSLLLLK--------ADATVSIVHSR 350 TP G E++ R+G+ GK+ VV GRS VG+P+++LL DATV+I H Sbjct: 169 ATPWGVWEIIKRTGIPTLGKNVVVAGRSKNVGMPIAMLLHTDGAHERPGGDATVTISHRY 228 Query: 351 TPNPE----TIVCQADIVIAAAGQAMMIKGDWIKPGAAVIDVGTNSIDDPTRKSGYRLVG 518 TP + TI+ ADIVI+AAG +I D IK GAAVIDVG N + DP +LVG Sbjct: 229 TPKEQLKKHTIL--ADIVISAAGIPNLITADMIKEGAAVIDVGINRVHDPVTAKP-KLVG 285 Query: 519 DVDFAEASKVAGHLTP 566 DVDF + AG++TP Sbjct: 286 DVDFEGVRQKAGYITP 301
>MTDC_CHICK (Q5ZKA5) Bifunctional methylenetetrahydrofolate| dehydrogenase/cyclohydrolase, mitochondrial precursor [Includes: NAD-dependent methylenetetrahydrofolate dehydrogenase (EC 1.5.1.15); Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9)] Length = 337 Score = 156 bits (395), Expect = 3e-38 Identities = 91/195 (46%), Positives = 122/195 (62%), Gaps = 11/195 (5%) Frame = +3 Query: 15 VHRLNADPAVHGILVQLPLPKHINEEIILNQISIEKDVDGFHPLNIGKLAMKGRNPLFLP 194 + +LN D V G+LVQLPLP+HI+E I N ++ +KDVDGFH +N+G++ + + LP Sbjct: 112 ISKLNNDANVDGLLVQLPLPEHIDERKICNAVTPDKDVDGFHVINVGRMCLDQYS--MLP 169 Query: 195 CTPKGCMELLSRSGVTVKGKHAVVVGRSNIVGLPVSLLLLK--------ADATVSIVHSR 350 TP G E++ R+G+ GK+ VV GRS VG+P+++LL DATV+I H Sbjct: 170 ATPWGVWEIIKRTGIPTLGKNVVVAGRSKNVGMPIAMLLHTDGRHERPGGDATVTISHRY 229 Query: 351 TPNPE--TIVCQADIVIAAAGQAMMIKGDWIKPGAAVIDVGTNSIDDP-TRKSGYRLVGD 521 TP + +ADIV+AAAG +I D IK GAAVIDVG + DP T KS RLVGD Sbjct: 230 TPKEQLKQHTIRADIVVAAAGIPNLITADMIKEGAAVIDVGITRVQDPITAKS--RLVGD 287 Query: 522 VDFAEASKVAGHLTP 566 VDF K A ++TP Sbjct: 288 VDFEGVKKKASYITP 302
>FOLD_RICPR (Q9ZD32) FolD bifunctional protein [Includes:| Methylenetetrahydrofolate dehydrogenase (EC 1.5.1.5); Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9)] Length = 286 Score = 156 bits (395), Expect = 3e-38 Identities = 82/188 (43%), Positives = 116/188 (61%) Frame = +3 Query: 3 LVAEVHRLNADPAVHGILVQLPLPKHINEEIILNQISIEKDVDGFHPLNIGKLAMKGRNP 182 L+ +++ LN D + GI+VQLPLP I+E IL+ + KD DGFHPLN+G L G N Sbjct: 79 LILKINELNLDKGISGIIVQLPLPSSIDENKILSAVLPSKDSDGFHPLNVGYLH-SGINQ 137 Query: 183 LFLPCTPKGCMELLSRSGVTVKGKHAVVVGRSNIVGLPVSLLLLKADATVSIVHSRTPNP 362 F+PCT GC+ ++ + + GK AV+VGRSNIVG P+S LLL+ + +V+I HS+T N Sbjct: 138 GFIPCTALGCLAVIKKYAPNLNGKDAVIVGRSNIVGKPLSALLLQENCSVTICHSKTCNL 197 Query: 363 ETIVCQADIVIAAAGQAMMIKGDWIKPGAAVIDVGTNSIDDPTRKSGYRLVGDVDFAEAS 542 +I +ADIV+ A G + + ++ P A VIDVG N I S ++ GDVDF Sbjct: 198 SSITSKADIVVVAIGSPLKLTAEYFNPEAIVIDVGINRI------SHNKIAGDVDFENVK 251 Query: 543 KVAGHLTP 566 ++TP Sbjct: 252 SKVKYITP 259
>FOLD_SALTY (P58688) FolD bifunctional protein [Includes:| Methylenetetrahydrofolate dehydrogenase (EC 1.5.1.5); Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9)] Length = 287 Score = 155 bits (392), Expect = 8e-38 Identities = 86/188 (45%), Positives = 118/188 (62%) Frame = +3 Query: 3 LVAEVHRLNADPAVHGILVQLPLPKHINEEIILNQISIEKDVDGFHPLNIGKLAMKGRNP 182 L+A + LNAD + GILVQLPLP I+ +L +I+ +KDVDGFHP N+G+L R P Sbjct: 78 LLALIDTLNADNTIDGILVQLPLPAGIDNVKVLERIAPDKDVDGFHPYNVGRLCQ--RAP 135 Query: 183 LFLPCTPKGCMELLSRSGVTVKGKHAVVVGRSNIVGLPVSLLLLKADATVSIVHSRTPNP 362 PCTP+G + LL R + G +AVV+G SNIVG P+S+ LL A T ++ H T + Sbjct: 136 RLRPCTPRGIVTLLERYNIDTYGLNAVVIGASNIVGRPMSMELLLAGCTTTVTHRFTKDL 195 Query: 363 ETIVCQADIVIAAAGQAMMIKGDWIKPGAAVIDVGTNSIDDPTRKSGYRLVGDVDFAEAS 542 V AD++I A G+ I G+WIK GA VIDVG N +++ ++VGDV F EA+ Sbjct: 196 RHHVEHADLLIVAVGKPGFIPGEWIKEGAIVIDVGINRLENG------KVVGDVVFDEAA 249 Query: 543 KVAGHLTP 566 A ++TP Sbjct: 250 ARASYITP 257
>FOLD_SALTI (Q60006) FolD bifunctional protein [Includes:| Methylenetetrahydrofolate dehydrogenase (EC 1.5.1.5); Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9)] Length = 287 Score = 155 bits (392), Expect = 8e-38 Identities = 86/188 (45%), Positives = 118/188 (62%) Frame = +3 Query: 3 LVAEVHRLNADPAVHGILVQLPLPKHINEEIILNQISIEKDVDGFHPLNIGKLAMKGRNP 182 L+A + LNAD + GILVQLPLP I+ +L +I+ +KDVDGFHP N+G+L R P Sbjct: 78 LLALIDTLNADNTIDGILVQLPLPAGIDNVKVLERIAPDKDVDGFHPYNVGRLCQ--RAP 135 Query: 183 LFLPCTPKGCMELLSRSGVTVKGKHAVVVGRSNIVGLPVSLLLLKADATVSIVHSRTPNP 362 PCTP+G + LL R + G +AVV+G SNIVG P+S+ LL A T ++ H T + Sbjct: 136 RLRPCTPRGIVTLLERYNIDTYGLNAVVIGASNIVGRPMSMELLLAGCTTTVTHRFTKDL 195 Query: 363 ETIVCQADIVIAAAGQAMMIKGDWIKPGAAVIDVGTNSIDDPTRKSGYRLVGDVDFAEAS 542 V AD++I A G+ I G+WIK GA VIDVG N +++ ++VGDV F EA+ Sbjct: 196 RHHVEHADLLIVAVGKPGFIPGEWIKEGAIVIDVGINRLENG------KVVGDVVFDEAA 249 Query: 543 KVAGHLTP 566 A ++TP Sbjct: 250 ARASYITP 257
>FOLD_BUCAP (Q8K979) FolD bifunctional protein [Includes:| Methylenetetrahydrofolate dehydrogenase (EC 1.5.1.5); Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9)] Length = 285 Score = 153 bits (387), Expect = 3e-37 Identities = 83/184 (45%), Positives = 112/184 (60%) Frame = +3 Query: 15 VHRLNADPAVHGILVQLPLPKHINEEIILNQISIEKDVDGFHPLNIGKLAMKGRNPLFLP 194 + +LN + + GILVQLP+PK IN I + I +KDVDGFHP N G L RNP Sbjct: 83 IEKLNNNINIDGILVQLPIPKQINYYKIFSSIRPDKDVDGFHPYNTGSLCQ--RNPTLRA 140 Query: 195 CTPKGCMELLSRSGVTVKGKHAVVVGRSNIVGLPVSLLLLKADATVSIVHSRTPNPETIV 374 CTPKG + +L+ + + G +AV+VG SNIVG P+S+ LL A T ++ H T N + Sbjct: 141 CTPKGIITMLNYTKIKTHGLNAVMVGASNIVGRPMSMELLLAGCTTTVTHRFTKNLRHHI 200 Query: 375 CQADIVIAAAGQAMMIKGDWIKPGAAVIDVGTNSIDDPTRKSGYRLVGDVDFAEASKVAG 554 AD+++ A G+ + GDWIK GA VIDVG N + D + +VGDVDF AS A Sbjct: 201 KNADLLVVAIGKPNFLHGDWIKEGAIVIDVGINKLKDGS------IVGDVDFKSASLKAA 254 Query: 555 HLTP 566 ++TP Sbjct: 255 YITP 258
>FOLD_BUCAI (P57557) FolD bifunctional protein [Includes:| Methylenetetrahydrofolate dehydrogenase (EC 1.5.1.5); Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9)] Length = 285 Score = 151 bits (382), Expect = 1e-36 Identities = 85/184 (46%), Positives = 113/184 (61%) Frame = +3 Query: 15 VHRLNADPAVHGILVQLPLPKHINEEIILNQISIEKDVDGFHPLNIGKLAMKGRNPLFLP 194 + +LN + + GIL+QLPLP IN IL+ I +KDVDGFHP N G L R P Sbjct: 83 ISKLNENKNIDGILIQLPLPPQINHMKILSSIVPDKDVDGFHPYNTGSLCQ--RTPKLRA 140 Query: 195 CTPKGCMELLSRSGVTVKGKHAVVVGRSNIVGLPVSLLLLKADATVSIVHSRTPNPETIV 374 CTPKG + +L + + G HAV+VG SNIVG P+SL LL A T ++ H T N + V Sbjct: 141 CTPKGIITMLKYNKIKTHGLHAVMVGASNIVGRPMSLELLLAGCTTTVTHRFTKNLKDHV 200 Query: 375 CQADIVIAAAGQAMMIKGDWIKPGAAVIDVGTNSIDDPTRKSGYRLVGDVDFAEASKVAG 554 AD++I A G+A +KG WIK G+ VIDVG N + K+G ++VGDV+F A A Sbjct: 201 QNADLLIVAVGKANFLKGSWIKTGSIVIDVGINRL-----KNG-KVVGDVEFKTAYLRAS 254 Query: 555 HLTP 566 ++TP Sbjct: 255 YITP 258
>FOLD_THEAC (Q05213) Probable folD bifunctional protein [Includes:| Methylenetetrahydrofolate dehydrogenase (EC 1.5.1.5); Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9)] Length = 276 Score = 105 bits (262), Expect = 9e-23 Identities = 59/188 (31%), Positives = 102/188 (54%) Frame = +3 Query: 3 LVAEVHRLNADPAVHGILVQLPLPKHINEEIILNQISIEKDVDGFHPLNIGKLAMKGRNP 182 L+ + L DP ++GI+++ PLPK + I+ I KDVD P N G +A+ Sbjct: 72 LLKRIDDLAKDPQINGIMIENPLPKGFDYYEIVRNIPYYKDVDALSPYNQGLIALN--RE 129 Query: 183 LFLPCTPKGCMELLSRSGVTVKGKHAVVVGRSNIVGLPVSLLLLKADATVSIVHSRTPNP 362 +P TP+ ++++ G +V RS +VG P+S++LL + TVS+ HS+T + Sbjct: 130 FLVPATPRAVIDIMDYYGY--HENTVTIVNRSPVVGRPLSMMLLNRNYTVSVCHSKTKDI 187 Query: 363 ETIVCQADIVIAAAGQAMMIKGDWIKPGAAVIDVGTNSIDDPTRKSGYRLVGDVDFAEAS 542 ++ + IV+ A G+ + + + PG+ VIDVG N ++D ++VGD +F + S Sbjct: 188 GSMTRSSKIVVVAVGRPGFLNREMVTPGSVVIDVGINYVND-------KVVGDANFEDLS 240 Query: 543 KVAGHLTP 566 + +TP Sbjct: 241 EYVEAITP 248
>FOLD_MYCPN (P75096) FolD bifunctional protein [Includes:| Methylenetetrahydrofolate dehydrogenase (EC 1.5.1.5); Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9)] Length = 269 Score = 69.7 bits (169), Expect = 5e-12 Identities = 57/189 (30%), Positives = 81/189 (42%), Gaps = 1/189 (0%) Frame = +3 Query: 3 LVAEVHRLNADPAVHGILVQLPLPKHINEEIILNQISIEKDVDGFHPLNIGKLAMKGRNP 182 L+ ++ +LN DP V GI++QLP+ H+ + +L I KDVD + G P Sbjct: 69 LLEKIQQLNTDPEVTGIILQLPVYPHLKQNKLLKAIDPYKDVD----------YLTGNCP 118 Query: 183 L-FLPCTPKGCMELLSRSGVTVKGKHAVVVGRSNIVGLPVSLLLLKADATVSIVHSRTPN 359 L C + + L K VVVG G P+ L + V TPN Sbjct: 119 LPIRSCVVEAVLILKEHFHHDFTNKQIVVVGLGVTGGGPIFHYLKETGHQVVGCDKHTPN 178 Query: 360 PETIVCQADIVIAAAGQAMMIKGDWIKPGAAVIDVGTNSIDDPTRKSGYRLVGDVDFAEA 539 ++ AD+VI A G+ K KPG + DVG +R +L GD+D Sbjct: 179 TMELIKTADVVITAIGKPHFFKTTNFKPGVILYDVGV------SRNVLNKLCGDIDPNGI 232 Query: 540 SKVAGHLTP 566 KVA +P Sbjct: 233 EKVAKWWSP 241
>FOLD_MYCGE (P47259) FolD bifunctional protein [Includes:| Methylenetetrahydrofolate dehydrogenase (EC 1.5.1.5); Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9)] Length = 273 Score = 65.1 bits (157), Expect = 1e-10 Identities = 46/175 (26%), Positives = 78/175 (44%) Frame = +3 Query: 3 LVAEVHRLNADPAVHGILVQLPLPKHINEEIILNQISIEKDVDGFHPLNIGKLAMKGRNP 182 L+ ++ LN D V GI++QLP+ H+++ +L I+ KDVDG ++ ++ Sbjct: 69 LIEKIISLNHDVNVTGIILQLPVYPHLDKNSLLEAINPLKDVDGLTTNHLAEIK------ 122 Query: 183 LFLPCTPKGCMELLSRSGVTVKGKHAVVVGRSNIVGLPVSLLLLKADATVSIVHSRTPNP 362 PC + + L + + VVVG G P+ L + V TPN Sbjct: 123 ---PCIVEAIITLKELFNLEFNNQKIVVVGLGITGGKPIYEFLKTSGYKVQACDKDTPNT 179 Query: 363 ETIVCQADIVIAAAGQAMMIKGDWIKPGAAVIDVGTNSIDDPTRKSGYRLVGDVD 527 ++ ADIV A G++ + K G + D+G +R +L GD++ Sbjct: 180 FELIKSADIVFTAIGKSHFFQAKNFKKGVILFDIGV------SRNKQNKLCGDIN 228
>MTD1_YEAST (Q02046) Methylenetetrahydrofolate dehydrogenase [NAD+] (EC| 1.5.1.15) Length = 320 Score = 55.5 bits (132), Expect = 1e-07 Identities = 36/118 (30%), Positives = 58/118 (49%), Gaps = 16/118 (13%) Frame = +3 Query: 27 NADPAVHGILVQLPLPKHINEEIILNQISIEKDVDGFHPL-------NIGKLAMKGRNPL 185 N D +V+GI+V P+ + ++ + + EKDV+G + + N+ L + R Sbjct: 87 NGDDSVNGIMVYFPVFGNAQDQYLQQVVCKEKDVEGLNHVYYQNLYHNVRYLDKENRLKS 146 Query: 186 FLPCTPKGCMELLS---------RSGVTVKGKHAVVVGRSNIVGLPVSLLLLKADATV 332 LPCTP +++L G + GK +V+ RS IVG P++ LL ATV Sbjct: 147 ILPCTPLAIVKILEFLKIYNNLLPEGNRLYGKKCIVINRSEIVGRPLAALLANDGATV 204
>OCD2_RHIME (P58339) Ornithine cyclodeaminase 2 (EC 4.3.1.12) (OCD 2)| Length = 342 Score = 35.0 bits (79), Expect = 0.15 Identities = 13/33 (39%), Positives = 23/33 (69%), Gaps = 1/33 (3%) Frame = +3 Query: 378 QADIVIAAA-GQAMMIKGDWIKPGAAVIDVGTN 473 QADI+I G+ +++ DW+KPG ++ +GT+ Sbjct: 208 QADILITTTRGKGSLVEADWVKPGTHIVAIGTD 240
>RL2_BORBU (P94270) 50S ribosomal protein L2| Length = 277 Score = 33.9 bits (76), Expect = 0.33 Identities = 19/64 (29%), Positives = 27/64 (42%), Gaps = 1/64 (1%) Frame = +2 Query: 287 GFTSIPSPSESRRYRVDRAFTDAKSRNDCLXXXXXXXXXXPGHDDQGRLDQTRR-GSHRC 463 G + + S RY+ +F D ND L G D GR+ RR G H+ Sbjct: 2 GIKTYKPKTSSLRYKTTLSFDDLSKGNDPLKSLTKGKKFKSGRDSSGRISIRRRGGGHKR 61 Query: 464 RYKL 475 +Y+L Sbjct: 62 KYRL 65
>GP111_HUMAN (Q8IZF7) Probable G-protein coupled receptor 111 (G-protein coupled| receptor PGR20) Length = 708 Score = 32.3 bits (72), Expect = 0.96 Identities = 15/39 (38%), Positives = 19/39 (48%) Frame = -1 Query: 518 ANEPVPGLPGRVVDGVCTDIDDCRAWFDPVSLDHHGLAC 402 + E VP P V DGVCTD C P + + G +C Sbjct: 97 SKEKVPARPHGVCDGVCTDYSQCTQPCPPDTQGNMGFSC 135
>MDC1_RAT (Q5U2M8) Mediator of DNA damage checkpoint protein 1| Length = 1279 Score = 31.6 bits (70), Expect = 1.6 Identities = 32/144 (22%), Positives = 53/144 (36%), Gaps = 20/144 (13%) Frame = -2 Query: 553 PATLLASAKSTSPTSLYPDFLVGSSMEFVPTSMTAAPGL----------------IQSPL 422 P + ++ ++ P+ +V + E P++ T PG+ + P Sbjct: 873 PTSRPTRGRANRSSTRTPELIVPTGPELQPSTSTEQPGIPNLTSQVTEGRAHSTSVNMPE 932 Query: 421 IIMAWPAAAMTMSA*QTIVSGFGVRE--CTIDTV--ASAFRRRRDTGKPTMLLRPTTTAC 254 ++ P A SA Q++ S R T++ V S RRRR TGK P Sbjct: 933 PVLTGPEAQPLTSAEQSVTSNLNPRAQPLTLEPVPQTSHQRRRRATGKQGSRTAPVGPKS 992 Query: 253 FPFTVTPLRDRSSMQPFGVQGRNS 182 + P S+ Q G +S Sbjct: 993 YSTPAEPEPQSSASQSSGASEADS 1016
>CD97_MOUSE (Q9Z0M6) CD97 antigen precursor| Length = 818 Score = 31.2 bits (69), Expect = 2.1 Identities = 16/44 (36%), Positives = 20/44 (45%) Frame = -1 Query: 512 EPVPGLPGRVVDGVCTDIDDCRAWFDPVSLDHHGLACCCNDNVC 381 +PVPG P V VC D+D+C + G C N VC Sbjct: 198 KPVPGSPNGPVSTVCEDVDECSS----------GQHQCHNSTVC 231
>LRP2_HUMAN (P98164) Low-density lipoprotein receptor-related protein 2 precursor| (Megalin) (Glycoprotein 330) (gp330) Length = 4655 Score = 30.8 bits (68), Expect = 2.8 Identities = 13/33 (39%), Positives = 17/33 (51%) Frame = -1 Query: 479 DGVCTDIDDCRAWFDPVSLDHHGLACCCNDNVC 381 D VC D DDC W D + + G C +N+C Sbjct: 3944 DNVCDDADDCGDWSDELGC-NKGKERTCAENIC 3975
>Y432_LISMO (P25145) Hypothetical oxidoreductase Lmo0432 (EC 1.-.-.-) (ORFA)| Length = 248 Score = 30.8 bits (68), Expect = 2.8 Identities = 20/68 (29%), Positives = 34/68 (50%) Frame = +3 Query: 237 VTVKGKHAVVVGRSNIVGLPVSLLLLKADATVSIVHSRTPNPETIVCQADIVIAAAGQAM 416 +T+K K ++ G S+ +G +LLL + A + + R E IV + A +G+A+ Sbjct: 1 MTIKNKVIIITGASSGIGKATALLLAEKGAKLVLAARRVEKLEKIV---QTIKANSGEAI 57 Query: 417 MIKGDWIK 440 K D K Sbjct: 58 FAKTDVTK 65
>DCUD_ECOLI (P45428) Putative cryptic C4-dicarboxylate transporter dcuD| Length = 455 Score = 30.4 bits (67), Expect = 3.6 Identities = 16/43 (37%), Positives = 24/43 (55%) Frame = +3 Query: 387 IVIAAAGQAMMIKGDWIKPGAAVIDVGTNSIDDPTRKSGYRLV 515 +V+AAAG +M+ G W+ G + DPT+ SGY +V Sbjct: 26 VVLAAAGIFLMMCGVWL---------GFGGVLDPTKSSGYLIV 59
>EFG1_PONPY (Q5R9V1) Elongation factor G 1, mitochondrial precursor (mEF-G 1)| (Elongation factor G1) Length = 751 Score = 30.4 bits (67), Expect = 3.6 Identities = 21/63 (33%), Positives = 27/63 (42%), Gaps = 4/63 (6%) Frame = -2 Query: 376 QTIVSGFGVRECTIDTVASAFRRRRD----TGKPTMLLRPTTTACFPFTVTPLRDRSSMQ 209 +TI+SG G E ++ A R TGKP + R T TA PF T R Sbjct: 490 ETIISGMG--ELHLEIYAQRLEREYGCPCITGKPKVAFRETITAPVPFDFTHKRQSGGAG 547 Query: 208 PFG 200 +G Sbjct: 548 QYG 550
>MURE_BRUSU (Q8FZP0) UDP-N-acetylmuramoylalanyl-D-glutamate--2,| 6-diaminopimelate ligase (EC 6.3.2.13) (UDP-N-acetylmuramyl-tripeptide synthetase) (Meso-diaminopimelate-adding enzyme) (UDP-MurNAc-tripeptide synthetase) Length = 488 Score = 30.4 bits (67), Expect = 3.6 Identities = 27/119 (22%), Positives = 45/119 (37%), Gaps = 13/119 (10%) Frame = +3 Query: 246 KGKHAVVVGRSNIVGLPVSLLLLKADATVSIVHSRTPNPETIVC-------QADIVIAAA 404 +G A++ G+ + ADA V ++H P + Q ++++A Sbjct: 58 RGAVAIIAGKDTAI----------ADAGVPVLHVDDPRHVLAIAAAQFYGKQPEVMVAVT 107 Query: 405 GQ------AMMIKGDWIKPGAAVIDVGTNSIDDPTRKSGYRLVGDVDFAEASKVAGHLT 563 G A + W G ++GT + PTR S Y + D E +V LT Sbjct: 108 GTSGKTSVASFTRQIWAYAGFPAANIGTTGVFSPTR-SDYNSLTTPDPVELHRVLAELT 165
>EMR2_HUMAN (Q9UHX3) EGF-like module-containing mucin-like hormone| receptor-like 2 precursor (EGF-like module EMR2) (CD312 antigen) Length = 823 Score = 30.0 bits (66), Expect = 4.8 Identities = 22/73 (30%), Positives = 31/73 (42%), Gaps = 4/73 (5%) Frame = -1 Query: 512 EPVPGLPGRVVDGVCTDIDDCRAWFDPVSLDHHGLACCCNDNVCLTDNRFGIW----RP* 345 +P+PG P + VC D+D+C + G C + VC N G + RP Sbjct: 196 QPIPGSPNGPNNTVCEDVDECSS----------GQHQCDSSTVCF--NTVGSYSCRCRPG 243 Query: 344 MHDRHGSVCFQKE 306 RHG QK+ Sbjct: 244 WKPRHGIPNNQKD 256
>CD97_HUMAN (P48960) CD97 antigen precursor (Leukocyte antigen CD97)| Length = 835 Score = 30.0 bits (66), Expect = 4.8 Identities = 22/73 (30%), Positives = 31/73 (42%), Gaps = 4/73 (5%) Frame = -1 Query: 512 EPVPGLPGRVVDGVCTDIDDCRAWFDPVSLDHHGLACCCNDNVCLTDNRFGIW----RP* 345 +P+PG P + VC D+D+C + G C + VC N G + RP Sbjct: 193 QPIPGSPNGPNNTVCEDVDECSS----------GQHQCDSSTVCF--NTVGSYSCRCRPG 240 Query: 344 MHDRHGSVCFQKE 306 RHG QK+ Sbjct: 241 WKPRHGIPNNQKD 253
>NRG3_MOUSE (O35181) Pro-neuregulin-3, membrane-bound isoform precursor| (Pro-NRG3) [Contains: Neuregulin-3 (NRG-3)] Length = 713 Score = 30.0 bits (66), Expect = 4.8 Identities = 31/125 (24%), Positives = 47/125 (37%), Gaps = 2/125 (1%) Frame = -2 Query: 493 LVGSSMEFVPTSMTAAPGLIQSPLIIMAWPAAAMTMSA*QTIVSGFGVRECTIDTVASAF 314 +VGS E+VPT + + G+ Q P + + M T S + AS+ Sbjct: 90 VVGSVKEYVPTDLVDSKGMGQDPFFLSKPSSFPKAMETTTTTTSTTSPATPSAGGAASSR 149 Query: 313 RRRRDTGKPTMLLRPTTTACFPFTVTPLRDRSSMQPFGVQGRNSGFLPFIAS--LPMFKG 140 R + + T + R T FP P+R P RN+ P + S P F Sbjct: 150 TPNRISTRLTTITRAPTR--FPGHRVPIR----ASPRSTTARNTAAPPTVLSTTAPFFSS 203 Query: 139 *KPST 125 P + Sbjct: 204 STPGS 208
>TMEM5_HUMAN (Q9Y2B1) Transmembrane protein 5| Length = 443 Score = 29.6 bits (65), Expect = 6.2 Identities = 20/62 (32%), Positives = 29/62 (46%), Gaps = 2/62 (3%) Frame = +2 Query: 92 NYIKPDLH*ERCRWFSSFEHWQAR--NERQKSTVPTLYPKGLHGAPVTQWSHCKRKARSC 265 N +K D + + C W S+ EHWQ + NE K+ L L PV + C R +C Sbjct: 287 NILKKDGNDKLC-WVSAREHWQPQETNESLKNYQDALLQSDLTLCPVGVNTECYRIYEAC 345 Query: 266 GW 271 + Sbjct: 346 SY 347
>GID1_ORYSA (Q6L545) Gibberellin receptor GID1 (EC 3.-.-.-)| (Gibberellin-insensitive dwarf protein 1) (Protein GIBBERELLIN INSENSITIVE DWARF1) Length = 354 Score = 29.6 bits (65), Expect = 6.2 Identities = 14/30 (46%), Positives = 16/30 (53%) Frame = -2 Query: 229 RDRSSMQPFGVQGRNSGFLPFIASLPMFKG 140 RD + PFG GR G LPF SL + G Sbjct: 265 RDHPACNPFGPNGRRLGGLPFAKSLIIVSG 294
>RPOB_CHLCH (Q3ATP5) DNA-directed RNA polymerase beta chain (EC 2.7.7.6) (RNAP| beta subunit) (Transcriptase beta chain) (RNA polymerase beta subunit) Length = 1300 Score = 29.3 bits (64), Expect = 8.1 Identities = 23/108 (21%), Positives = 51/108 (47%), Gaps = 11/108 (10%) Frame = +3 Query: 90 EIILNQISIEK--DVDGFHPLNIG----KLAMKGRNPLFLPCTPKGCMELLSRSGVTVKG 251 +I+LN + + ++ + ++G KL +K + P+F T + L R+G+ G Sbjct: 1105 DIVLNPLGVPSRMNIGQLYETSLGWAAKKLGVKFKTPIFNGATYEEVQRELERAGLPTHG 1164 Query: 252 KHAVVVGRS-----NIVGLPVSLLLLKADATVSIVHSRTPNPETIVCQ 380 K ++ GR+ + V + +L + +H+R+ P +++ Q Sbjct: 1165 KVSLFDGRTGERFDDEVTVGYIYMLKLSHLVDDKIHARSTGPYSLITQ 1212 Database: uniprot_sprot.fasta Posted date: May 25, 2006 5:36 PM Number of letters in database: 80,573,946 Number of sequences in database: 219,361 Lambda K H 0.318 0.135 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 87,391,507 Number of Sequences: 219361 Number of extensions: 1976513 Number of successful extensions: 6127 Number of sequences better than 10.0: 48 Number of HSP's better than 10.0 without gapping: 5769 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 6064 length of database: 80,573,946 effective HSP length: 106 effective length of database: 57,321,680 effective search space used: 4700377760 frameshift window, decay const: 50, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
