ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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| Clone Name | bah62m03 |
|---|---|
| Clone Library Name | barley_pub |
>BUR1_EMENI (Q96VK3) Serine/threonine-protein kinase bur1 (EC 2.7.11.22) (EC| 2.7.11.23) (Pitalre-like kinase A) Length = 544 Score = 100 bits (248), Expect = 4e-21 Identities = 53/118 (44%), Positives = 71/118 (60%), Gaps = 6/118 (5%) Frame = +2 Query: 224 FEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRFMAREIHILRRLDNPNV 403 FE L K+G+GT+ VYKAR +G IVALKK+ N REI +L+ L + N+ Sbjct: 25 FEFLGKLGEGTFGEVYKARAKRDGSIVALKKILMHNERDGFPITALREIKLLKMLSHTNI 84 Query: 404 IKLEGLVTSRMSS------SLYLVFEYMEHDLAGLAATPGIKFTEAQVKCYMQQLLSG 559 ++L + R S+Y+VF YMEHDL+GL P + F+EAQ+KCYM QLL G Sbjct: 85 MQLREMAVERSKGEGRKKPSMYMVFPYMEHDLSGLLENPEVHFSEAQIKCYMIQLLEG 142
>BUR1_ASPFU (Q4WTN5) Serine/threonine-protein kinase bur1 (EC 2.7.11.22) (EC| 2.7.11.23) Length = 580 Score = 100 bits (248), Expect = 4e-21 Identities = 52/118 (44%), Positives = 71/118 (60%), Gaps = 6/118 (5%) Frame = +2 Query: 224 FEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRFMAREIHILRRLDNPNV 403 FE L K+G+GT+ VYKAR ++G IVALKK+ N REI +L+ L + N+ Sbjct: 25 FEFLGKLGEGTFGEVYKARSKKDGSIVALKKILMHNEKDGFPITALREIKLLKMLSHRNI 84 Query: 404 IKLEGLVTSRMSS------SLYLVFEYMEHDLAGLAATPGIKFTEAQVKCYMQQLLSG 559 ++L+ + R S+Y+V YMEHDL+GL P + FTE Q+KCYM QLL G Sbjct: 85 LQLKEMAVERSKGDGRKKPSMYMVTPYMEHDLSGLLENPAVNFTEPQIKCYMLQLLEG 142
>CD2L7_HUMAN (Q9NYV4) Cell division cycle 2-related protein kinase 7 (EC| 2.7.11.22) (CDC2-related protein kinase 7) (Cdc2-related kinase, arginine/serine-rich) (CrkRS) Length = 1490 Score = 99.0 bits (245), Expect = 8e-21 Identities = 59/162 (36%), Positives = 89/162 (54%), Gaps = 8/162 (4%) Frame = +2 Query: 98 KPRIIDVPNGVVAEHVAAGWPRWLTEVATEAVRGWQPRKAESFEKLDKIGQGTYSSVYKA 277 +P+ I P + PR+ TE+ W R + F+ + IG+GTY VYKA Sbjct: 687 EPKAITPPQQPYKKRPKICCPRYGERRQTES--DWGKRCVDKFDIIGIIGEGTYGQVYKA 744 Query: 278 RDLENGKIVALKKVRFANMDPESVRFMAREIHILRRLDNPNVIKLEGLVTSRMSS----- 442 RD + G++VALKKVR N REI ILR+L + +V+ ++ +VT + + Sbjct: 745 RDKDTGELVALKKVRLDNEKEGFPITAIREIKILRQLIHRSVVNMKEIVTDKQDALDFKK 804 Query: 443 ---SLYLVFEYMEHDLAGLAATPGIKFTEAQVKCYMQQLLSG 559 + YLVFEYM+HDL GL + + F+E +K +M+QL+ G Sbjct: 805 DKGAFYLVFEYMDHDLMGLLESGLVHFSEDHIKSFMKQLMEG 846
>CD2L5_MOUSE (Q69ZA1) Cell division cycle 2-like protein kinase 5 (EC 2.7.11.22)| (CDC2-related protein kinase 5) Length = 1511 Score = 96.7 bits (239), Expect = 4e-20 Identities = 52/128 (40%), Positives = 76/128 (59%), Gaps = 8/128 (6%) Frame = +2 Query: 200 WQPRKAESFEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRFMAREIHIL 379 W R + F+ + IG+GTY VYKARD + G++VALKKVR N REI IL Sbjct: 697 WGKRCVDKFDIIGIIGEGTYGQVYKARDKDTGEMVALKKVRLDNEKEGFPITAIREIKIL 756 Query: 380 RRLDNPNVIKLEGLVTSRMSS--------SLYLVFEYMEHDLAGLAATPGIKFTEAQVKC 535 R+L + ++I ++ +VT + + + YLVFEYM+HDL GL + + F E +K Sbjct: 757 RQLTHQSIINMKEIVTDKEDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFNENHIKS 816 Query: 536 YMQQLLSG 559 +M+QL+ G Sbjct: 817 FMRQLMEG 824
>CD2L5_HUMAN (Q14004) Cell division cycle 2-like protein kinase 5 (EC 2.7.11.22)| (CDC2-related protein kinase 5) (Cholinesterase-related cell division controller) Length = 1512 Score = 96.7 bits (239), Expect = 4e-20 Identities = 52/128 (40%), Positives = 76/128 (59%), Gaps = 8/128 (6%) Frame = +2 Query: 200 WQPRKAESFEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRFMAREIHIL 379 W R + F+ + IG+GTY VYKARD + G++VALKKVR N REI IL Sbjct: 697 WGKRCVDKFDIIGIIGEGTYGQVYKARDKDTGEMVALKKVRLDNEKEGFPITAIREIKIL 756 Query: 380 RRLDNPNVIKLEGLVTSRMSS--------SLYLVFEYMEHDLAGLAATPGIKFTEAQVKC 535 R+L + ++I ++ +VT + + + YLVFEYM+HDL GL + + F E +K Sbjct: 757 RQLTHQSIINMKEIVTDKEDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFNENHIKS 816 Query: 536 YMQQLLSG 559 +M+QL+ G Sbjct: 817 FMRQLMEG 824
>CDK10_HUMAN (Q15131) Cell division protein kinase 10 (EC 2.7.11.22)| (Serine/threonine-protein kinase PISSLRE) Length = 360 Score = 96.3 bits (238), Expect = 5e-20 Identities = 52/117 (44%), Positives = 71/117 (60%) Frame = +2 Query: 209 RKAESFEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRFMAREIHILRRL 388 R + FEKL++IG+GTY VY+ARD + +IVALKKVR REI +L RL Sbjct: 34 RSVKEFEKLNRIGEGTYGIVYRARDTQTDEIVALKKVRMDKEKDGIPISSLREITLLLRL 93 Query: 389 DNPNVIKLEGLVTSRMSSSLYLVFEYMEHDLAGLAATPGIKFTEAQVKCYMQQLLSG 559 +PN+++L+ +V S++LV Y E DLA L F+EAQVKC + Q+L G Sbjct: 94 RHPNIVELKEVVVGNHLESIFLVMGYCEQDLASLLENMPTPFSEAQVKCIVLQVLRG 150
>CDK9_SCHPO (Q96WV9) Serine/threonine-protein kinase cdk9 (EC 2.7.11.1)| (Cyclin-dependent kinase cdk9) Length = 591 Score = 91.3 bits (225), Expect = 2e-18 Identities = 46/119 (38%), Positives = 74/119 (62%), Gaps = 7/119 (5%) Frame = +2 Query: 224 FEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRFMA-REIHILRRLDNPN 400 + ++K+G+GT+ VYK++ ++GK+ ALK++ + + E A REI IL+ + + N Sbjct: 36 YHLMEKLGEGTFGEVYKSQRRKDGKVYALKRI-LMHTEKEGFPITAIREIKILKSIKHEN 94 Query: 401 VIKLEGLVTSRMSS------SLYLVFEYMEHDLAGLAATPGIKFTEAQVKCYMQQLLSG 559 +I L + R S+Y+V YM+HDL+GL P +KFTE Q+KCYM+QL +G Sbjct: 95 IIPLSDMTVVRADKKHRRRGSIYMVTPYMDHDLSGLLENPSVKFTEPQIKCYMKQLFAG 153
>CDK9_CHICK (Q5ZKN1) Cell division protein kinase 9 (EC 2.7.11.22) (EC| 2.7.11.23) (Cyclin-dependent kinase 9) Length = 372 Score = 90.9 bits (224), Expect = 2e-18 Identities = 52/122 (42%), Positives = 73/122 (59%), Gaps = 6/122 (4%) Frame = +2 Query: 212 KAESFEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRFMAREIHILRRLD 391 + +EKL KIGQGT+ V+KA+ + GK VALKKV N REI IL+ L Sbjct: 15 EVSKYEKLAKIGQGTFGEVFKAKHRQTGKKVALKKVLMENEKEGFPITALREIKILQLLK 74 Query: 392 NPNVIKLEGLVTSRMS------SSLYLVFEYMEHDLAGLAATPGIKFTEAQVKCYMQQLL 553 + NV+ L + ++ S S+YLVF++ EHDLAGL + +KFT +++K MQ LL Sbjct: 75 HENVVNLIEICRTKASPYNRCKGSIYLVFDFCEHDLAGLLSNTHVKFTLSEIKKVMQMLL 134 Query: 554 SG 559 +G Sbjct: 135 NG 136
>BUR1_NEUCR (Q871M9) Serine/threonine-protein kinase bur-1 (EC 2.7.11.22) (EC| 2.7.11.23) Length = 545 Score = 90.5 bits (223), Expect = 3e-18 Identities = 48/119 (40%), Positives = 70/119 (58%), Gaps = 7/119 (5%) Frame = +2 Query: 224 FEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRFMAREIHILRRLDNPNV 403 +E L K+G+GT+ V++AR + G +VALKK+ N REI +L+ L + NV Sbjct: 26 YEVLGKLGEGTFGEVHRARSRKTGALVALKKIIMHNERDGFPITALREIKLLKLLSHKNV 85 Query: 404 IKLEGLVTS-------RMSSSLYLVFEYMEHDLAGLAATPGIKFTEAQVKCYMQQLLSG 559 ++LE + R +Y+V YM+HDL+GL P ++FTE QVKCY+ QLL G Sbjct: 86 LRLEEMAIEHPPRTDKRTRPIVYMVTPYMDHDLSGLLDNPSVRFTEPQVKCYLLQLLEG 144
>CDK9_HUMAN (P50750) Cell division protein kinase 9 (EC 2.7.11.22) (EC| 2.7.11.23) (Cyclin-dependent kinase 9) (Serine/threonine-protein kinase PITALRE) (C-2K) (Cell division cycle 2-like protein kinase 4) Length = 372 Score = 89.0 bits (219), Expect = 8e-18 Identities = 52/122 (42%), Positives = 73/122 (59%), Gaps = 6/122 (4%) Frame = +2 Query: 212 KAESFEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRFMAREIHILRRLD 391 + +EKL KIGQGT+ V+KAR + G+ VALKKV N REI IL+ L Sbjct: 15 EVSKYEKLAKIGQGTFGEVFKARHRKTGQKVALKKVLMENEKEGFPITALREIKILQLLK 74 Query: 392 NPNVIKLEGLVTSRMS------SSLYLVFEYMEHDLAGLAATPGIKFTEAQVKCYMQQLL 553 + NV+ L + ++ S S+YLVF++ EHDLAGL + +KFT +++K MQ LL Sbjct: 75 HENVVNLIEICRTKASPYNRCKGSIYLVFDFCEHDLAGLLSNVLVKFTLSEIKRVMQMLL 134 Query: 554 SG 559 +G Sbjct: 135 NG 136
>CDK9_RAT (Q641Z4) Cell division protein kinase 9 (EC 2.7.11.22) (EC| 2.7.11.23) (Cyclin-dependent kinase 9) Length = 372 Score = 87.8 bits (216), Expect = 2e-17 Identities = 51/118 (43%), Positives = 72/118 (61%), Gaps = 6/118 (5%) Frame = +2 Query: 224 FEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRFMAREIHILRRLDNPNV 403 +EKL KIGQGT+ V+KA+ + G+ VALKKV N REI IL+ L + NV Sbjct: 19 YEKLAKIGQGTFGEVFKAKHRQTGQKVALKKVLMENEKEGFPITALREIKILQLLKHENV 78 Query: 404 IKLEGLVTSRMS------SSLYLVFEYMEHDLAGLAATPGIKFTEAQVKCYMQQLLSG 559 + L + ++ S S+YLVF++ EHDLAGL + +KFT +++K MQ LL+G Sbjct: 79 VNLIEICRTKASPYNRCKGSIYLVFDFCEHDLAGLLSNVLVKFTLSEIKRVMQMLLNG 136
>CDK9_MOUSE (Q99J95) Cell division protein kinase 9 (EC 2.7.11.22) (EC| 2.7.11.23) (Cyclin-dependent kinase 9) Length = 372 Score = 87.8 bits (216), Expect = 2e-17 Identities = 51/118 (43%), Positives = 72/118 (61%), Gaps = 6/118 (5%) Frame = +2 Query: 224 FEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRFMAREIHILRRLDNPNV 403 +EKL KIGQGT+ V+KA+ + G+ VALKKV N REI IL+ L + NV Sbjct: 19 YEKLAKIGQGTFGEVFKAKHRQTGQKVALKKVLMENEKEGFPITALREIKILQLLKHENV 78 Query: 404 IKLEGLVTSRMS------SSLYLVFEYMEHDLAGLAATPGIKFTEAQVKCYMQQLLSG 559 + L + ++ S S+YLVF++ EHDLAGL + +KFT +++K MQ LL+G Sbjct: 79 VNLIEICRTKASPYNRCKGSIYLVFDFCEHDLAGLLSNVLVKFTLSEIKRVMQMLLNG 136
>CDK9_BOVIN (Q5EAB2) Cell division protein kinase 9 (EC 2.7.11.22) (EC| 2.7.11.23) (Cyclin-dependent kinase 9) Length = 372 Score = 87.4 bits (215), Expect = 2e-17 Identities = 51/118 (43%), Positives = 72/118 (61%), Gaps = 6/118 (5%) Frame = +2 Query: 224 FEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRFMAREIHILRRLDNPNV 403 +EKL KIGQGT+ V+KA+ + G+ VALKKV N REI IL+ L + NV Sbjct: 19 YEKLAKIGQGTFGEVFKAKHRKTGQKVALKKVLMENEKEGFPITALREIKILQLLKHENV 78 Query: 404 IKLEGLVTSRMS------SSLYLVFEYMEHDLAGLAATPGIKFTEAQVKCYMQQLLSG 559 + L + ++ S S+YLVF++ EHDLAGL + +KFT +++K MQ LL+G Sbjct: 79 VNLIEICRTKASPYNRCKGSIYLVFDFCEHDLAGLLSNVLVKFTLSEIKRVMQMLLNG 136
>CDK9B_XENLA (Q7ZX42) Cell division protein kinase 9-B (EC 2.7.11.22) (EC| 2.7.11.23) (Cyclin-dependent kinase 9-B) Length = 376 Score = 87.4 bits (215), Expect = 2e-17 Identities = 50/126 (39%), Positives = 74/126 (58%), Gaps = 10/126 (7%) Frame = +2 Query: 212 KAESFEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRFMAREIHILRRLD 391 + +E+L KIGQGT+ V+KA+ + GK VALKKV N REI IL+ L Sbjct: 15 EVSKYERLAKIGQGTFGEVFKAKHRQTGKKVALKKVLMENEKEGFPITALREIKILQLLK 74 Query: 392 NPNVIKLEGLVTSRMS----------SSLYLVFEYMEHDLAGLAATPGIKFTEAQVKCYM 541 + NV+ L + +++S +++LVF++ EHDLAGL + +KFT A++K M Sbjct: 75 HENVVHLIEICRNKISPTANQYNRCKGTIFLVFDFCEHDLAGLLSNAHVKFTVAEIKKVM 134 Query: 542 QQLLSG 559 Q LL+G Sbjct: 135 QMLLNG 140
>CDK2_XENLA (P23437) Cell division protein kinase 2 (EC 2.7.11.22) (CDC2| homolog Eg1 protein kinase) Length = 297 Score = 86.7 bits (213), Expect = 4e-17 Identities = 52/116 (44%), Positives = 75/116 (64%), Gaps = 2/116 (1%) Frame = +2 Query: 218 ESFEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRFMA-REIHILRRLDN 394 E+F+K++KIG+GTY VYKAR+ E G+IVALKK+R + + E V A REI +L+ L++ Sbjct: 2 ENFQKVEKIGEGTYGVVYKARNRETGEIVALKKIRL-DTETEGVPSTAIREISLLKELNH 60 Query: 395 PNVIKLEGLVTSRMSSSLYLVFEYMEHDLAGLAATPGIK-FTEAQVKCYMQQLLSG 559 PN++KL ++ + LYLVFE++ DL I + A VK Y+ QLL G Sbjct: 61 PNIVKLLDVI--HTENKLYLVFEFLNQDLKKFMDGSNISGISLALVKSYLFQLLQG 114
>CDK9_XENTR (Q6GLD8) Cell division protein kinase 9 (EC 2.7.11.22) (EC| 2.7.11.23) (Cyclin-dependent kinase 9) Length = 376 Score = 86.3 bits (212), Expect = 5e-17 Identities = 49/126 (38%), Positives = 74/126 (58%), Gaps = 10/126 (7%) Frame = +2 Query: 212 KAESFEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRFMAREIHILRRLD 391 + +E+L KIGQGT+ V+KA+ + GK VALKKV N REI IL+ L Sbjct: 15 EVSKYERLAKIGQGTFGEVFKAKHRQTGKKVALKKVLMENEKEGFPITALREIKILQLLK 74 Query: 392 NPNVIKLEGLVTSRMS----------SSLYLVFEYMEHDLAGLAATPGIKFTEAQVKCYM 541 + NV+ L + +++S +++LVF++ EHDLAGL + +KFT +++K M Sbjct: 75 HENVVNLIEICRTKISPTANQYNRCKGTIFLVFDFCEHDLAGLLSNAHVKFTLSEIKKVM 134 Query: 542 QQLLSG 559 Q LL+G Sbjct: 135 QMLLNG 140
>CDK9A_XENLA (Q4V862) Cell division protein kinase 9-A (EC 2.7.11.22) (EC| 2.7.11.23) (Cyclin-dependent kinase 9-A) Length = 376 Score = 86.3 bits (212), Expect = 5e-17 Identities = 49/126 (38%), Positives = 74/126 (58%), Gaps = 10/126 (7%) Frame = +2 Query: 212 KAESFEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRFMAREIHILRRLD 391 + +E+L KIGQGT+ V+KA+ + GK VALKKV N REI IL+ L Sbjct: 15 EVSKYERLAKIGQGTFGEVFKAKHRQTGKKVALKKVLMENEKEGFPITALREIKILQLLK 74 Query: 392 NPNVIKLEGLVTSRMS----------SSLYLVFEYMEHDLAGLAATPGIKFTEAQVKCYM 541 + NV+ L + +++S +++LVF++ EHDLAGL + +KFT +++K M Sbjct: 75 HENVVNLIEICRTKVSPTANQYNRCKGTIFLVFDFCEHDLAGLLSNAHVKFTLSEIKKVM 134 Query: 542 QQLLSG 559 Q LL+G Sbjct: 135 QMLLNG 140
>CDK3_HUMAN (Q00526) Cell division protein kinase 3 (EC 2.7.11.22)| Length = 305 Score = 85.5 bits (210), Expect = 9e-17 Identities = 49/116 (42%), Positives = 77/116 (66%), Gaps = 2/116 (1%) Frame = +2 Query: 218 ESFEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRFMA-REIHILRRLDN 394 + F+K++KIG+GTY VYKA++ E G++VALKK+R +++ E V A REI +L+ L + Sbjct: 2 DMFQKVEKIGEGTYGVVYKAKNRETGQLVALKKIRL-DLEMEGVPSTAIREISLLKELKH 60 Query: 395 PNVIKLEGLVTSRMSSSLYLVFEYMEHDLAG-LAATPGIKFTEAQVKCYMQQLLSG 559 PN+++L +V + LYLVFE++ DL + +TPG + +K Y+ QLL G Sbjct: 61 PNIVRLLDVVHN--ERKLYLVFEFLSQDLKKYMDSTPGSELPLHLIKSYLFQLLQG 114
>BUR1_GIBZE (Q4I5U9) Serine/threonine-protein kinase BUR1 (EC 2.7.11.22) (EC| 2.7.11.23) Length = 473 Score = 84.3 bits (207), Expect = 2e-16 Identities = 44/124 (35%), Positives = 69/124 (55%), Gaps = 8/124 (6%) Frame = +2 Query: 212 KAESFEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRFMAREIHILRRLD 391 + +E L K+G+GT+ V++AR + G +VALKK+ + REI +L+ L Sbjct: 33 RISDYELLGKLGEGTFGEVHRARLRKTGALVALKKIIMHHEKDGFPITALREIKLLKLLS 92 Query: 392 NPNVIKLEGLVTS--------RMSSSLYLVFEYMEHDLAGLAATPGIKFTEAQVKCYMQQ 547 + N+++LE + R +Y+ YM+HDL+GL P ++F E Q+KCYM Q Sbjct: 93 HKNILRLEDMAIEHPTRQTDKRKKPIVYMATPYMDHDLSGLLDNPSVQFKEPQIKCYMLQ 152 Query: 548 LLSG 559 LL G Sbjct: 153 LLEG 156
>CDC22_MEDSA (Q05006) Cell division control protein 2 homolog 2 (EC 2.7.11.22)| Length = 294 Score = 83.2 bits (204), Expect = 5e-16 Identities = 44/115 (38%), Positives = 70/115 (60%), Gaps = 1/115 (0%) Frame = +2 Query: 218 ESFEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRFMAREIHILRRLDNP 397 E +EK++KIG+GTY VYKARD + +ALKK+R D REI +L+ + + Sbjct: 2 EQYEKVEKIGEGTYGVVYKARDRATNETIALKKIRLEQEDEGVPSTAIREISLLKEMQHR 61 Query: 398 NVIKLEGLVTSRMSSSLYLVFEYMEHDLAG-LAATPGIKFTEAQVKCYMQQLLSG 559 N+++L+ +V S LYLVFEY++ DL + ++P + Q+K ++ Q+L G Sbjct: 62 NIVRLQDVVHS--EKRLYLVFEYLDLDLKKFMDSSPEFAKDQRQIKMFLYQILCG 114
>CDC2A_ARATH (P24100) Cell division control protein 2 homolog A (EC 2.7.11.22)| (EC 2.7.11.23) Length = 294 Score = 82.8 bits (203), Expect = 6e-16 Identities = 45/115 (39%), Positives = 68/115 (59%), Gaps = 1/115 (0%) Frame = +2 Query: 218 ESFEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRFMAREIHILRRLDNP 397 + +EK++KIG+GTY VYKARD + +ALKK+R D REI +L+ + + Sbjct: 2 DQYEKVEKIGEGTYGVVYKARDKVTNETIALKKIRLEQEDEGVPSTAIREISLLKEMQHS 61 Query: 398 NVIKLEGLVTSRMSSSLYLVFEYMEHDL-AGLAATPGIKFTEAQVKCYMQQLLSG 559 N++KL+ +V S LYLVFEY++ DL + +TP +K Y+ Q+L G Sbjct: 62 NIVKLQDVVHS--EKRLYLVFEYLDLDLKKHMDSTPDFSKDLHMIKTYLYQILRG 114
>BUR1_YARLI (Q6C842) Serine/threonine-protein kinase BUR1 (EC 2.7.11.22) (EC| 2.7.11.23) Length = 706 Score = 82.4 bits (202), Expect = 8e-16 Identities = 47/120 (39%), Positives = 66/120 (55%), Gaps = 6/120 (5%) Frame = +2 Query: 218 ESFEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRFMAREIHILRRLDNP 397 ES++ L KIG+GT+ V++A + + VALKK+ + REI IL+ L + Sbjct: 36 ESYKPLGKIGEGTFGEVFRAEQITTKRHVALKKILLHSEKEGFPVTALREIRILKLLRHE 95 Query: 398 NVIKLEGLVTSRMSSS------LYLVFEYMEHDLAGLAATPGIKFTEAQVKCYMQQLLSG 559 NVI L L R S +Y+V YM+HDLAGL ++ + A +KCYM QLL G Sbjct: 96 NVIPLVDLAVERGDQSKKERGCVYMVTPYMDHDLAGLLGNQSVQLSPAHIKCYMLQLLEG 155
>CDK9_CAEEL (Q9TVL3) Probable cell division protein kinase 9 (EC 2.7.11.22) (EC| 2.7.11.23) (Cyclin-dependent kinase 9) Length = 478 Score = 81.6 bits (200), Expect = 1e-15 Identities = 46/125 (36%), Positives = 68/125 (54%), Gaps = 8/125 (6%) Frame = +2 Query: 209 RKAESFEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRFMAREIHILRRL 388 R ++EKL+KIGQGT+ V+KAR G++VALKK+ N RE+ +L +L Sbjct: 80 RDVSTYEKLNKIGQGTFGEVFKARCKNTGRMVALKKILMENEKEGFPITALREVKMLEQL 139 Query: 389 DNPNV--------IKLEGLVTSRMSSSLYLVFEYMEHDLAGLAATPGIKFTEAQVKCYMQ 544 +PN+ K G S+ ++ YLV HDLAGL + P I+ + +K M+ Sbjct: 140 KHPNITDLIEVCSAKSTGTTGSKDRATFYLVMALCAHDLAGLLSNPKIRMSLVHIKTMMK 199 Query: 545 QLLSG 559 L+SG Sbjct: 200 HLMSG 204
>CDC2C_DROME (P23573) Cell division control protein 2 cognate (EC 2.7.11.22) (EC| 2.7.11.23) Length = 314 Score = 81.6 bits (200), Expect = 1e-15 Identities = 45/112 (40%), Positives = 66/112 (58%) Frame = +2 Query: 218 ESFEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRFMAREIHILRRLDNP 397 ++F++ +KIG+GTY VYKAR G+ VALKK+R REI +L+ L +P Sbjct: 6 DNFQRAEKIGEGTYGIVYKARSNSTGQDVALKKIRLEGETEGVPSTAIREISLLKNLKHP 65 Query: 398 NVIKLEGLVTSRMSSSLYLVFEYMEHDLAGLAATPGIKFTEAQVKCYMQQLL 553 NV++L +V S ++LY++FEY+ DL L FT +K YM Q+L Sbjct: 66 NVVQLFDVVIS--GNNLYMIFEYLNMDLKKLMDKKKDVFTPQLIKSYMHQIL 115
>CDC2_VIGAC (Q41639) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34cdc2) Length = 294 Score = 81.6 bits (200), Expect = 1e-15 Identities = 45/115 (39%), Positives = 69/115 (60%), Gaps = 1/115 (0%) Frame = +2 Query: 218 ESFEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRFMAREIHILRRLDNP 397 E +EK++KIG+GTY VYKARD + +ALKK+R D REI +L+ + + Sbjct: 2 EQYEKVEKIGEGTYGVVYKARDRVTNETIALKKIRLEQEDEGVPSTAIREISLLKEMQHR 61 Query: 398 NVIKLEGLVTSRMSSSLYLVFEYMEHDL-AGLAATPGIKFTEAQVKCYMQQLLSG 559 N+++L+ +V S LYLVFEY++ DL + ++P QVK ++ Q+L G Sbjct: 62 NIVRLQDVVHS--EKRLYLVFEYLDLDLKKHMDSSPEFVKDPRQVKMFLYQILCG 114
>CDK3_MOUSE (Q80YP0) Truncated cell division protein kinase 3 homolog| Length = 186 Score = 81.6 bits (200), Expect = 1e-15 Identities = 49/114 (42%), Positives = 73/114 (64%), Gaps = 2/114 (1%) Frame = +2 Query: 224 FEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRFMA-REIHILRRLDNPN 400 F+K++KIG+GTY VYKAR+ G++VALKK+R +++ E V A REI +L+ L +PN Sbjct: 4 FQKVEKIGEGTYGVVYKARNKVTGQLVALKKIRL-DLEAEGVPSTAVREISLLKELKHPN 62 Query: 401 VIKLEGLVTSRMSSSLYLVFEYMEHDL-AGLAATPGIKFTEAQVKCYMQQLLSG 559 +IKL +V LY+VFE++ DL + ++P + VK Y+ QLL G Sbjct: 63 IIKLLDVV--HREKKLYMVFEFLTQDLKRHMDSSPTSELPLPVVKSYLAQLLEG 114
>CC2H3_TRYBB (P54666) Cell division control protein 2 homolog 3 (EC 2.7.11.22)| Length = 311 Score = 81.6 bits (200), Expect = 1e-15 Identities = 43/114 (37%), Positives = 66/114 (57%) Frame = +2 Query: 218 ESFEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRFMAREIHILRRLDNP 397 + + ++D +G+GTY VY+A D G+IVALKKVR D + RE+ IL+ + +P Sbjct: 21 DRYNRMDILGEGTYGVVYRAVDRATGQIVALKKVRLDRTDEGIPQTALREVSILQEIHHP 80 Query: 398 NVIKLEGLVTSRMSSSLYLVFEYMEHDLAGLAATPGIKFTEAQVKCYMQQLLSG 559 N++ L ++ + LYL+FEY++HDL G FT +K + QLL G Sbjct: 81 NIVNLLDVICA--DGKLYLIFEYVDHDLKKALEKRGGAFTGTTLKKIIYQLLEG 132
>CDC2_VIGUN (P52389) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34cdc2) Length = 294 Score = 81.3 bits (199), Expect = 2e-15 Identities = 45/115 (39%), Positives = 69/115 (60%), Gaps = 1/115 (0%) Frame = +2 Query: 218 ESFEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRFMAREIHILRRLDNP 397 E +EK++KIG+GTY VYKARD + +ALKK+R D REI +L+ + + Sbjct: 2 EQYEKVEKIGEGTYGVVYKARDRVTDETIALKKIRLEQEDEGVPSTAIREISLLKEMQHR 61 Query: 398 NVIKLEGLVTSRMSSSLYLVFEYMEHDL-AGLAATPGIKFTEAQVKCYMQQLLSG 559 N+++L+ +V S LYLVFEY++ DL + ++P QVK ++ Q+L G Sbjct: 62 NIVRLQDVVHS--EKRLYLVFEYLDLDLKKHMDSSPEFVKDPRQVKMFLYQILCG 114
>CDK2_HUMAN (P24941) Cell division protein kinase 2 (EC 2.7.11.22) (p33 protein| kinase) Length = 298 Score = 81.3 bits (199), Expect = 2e-15 Identities = 50/118 (42%), Positives = 75/118 (63%), Gaps = 4/118 (3%) Frame = +2 Query: 218 ESFEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRFMA-REIHILRRLDN 394 E+F+K++KIG+GTY VYKAR+ G++VALKK+R + + E V A REI +L+ L++ Sbjct: 2 ENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRL-DTETEGVPSTAIREISLLKELNH 60 Query: 395 PNVIKLEGLVTSRMSSSLYLVFEYMEHDL---AGLAATPGIKFTEAQVKCYMQQLLSG 559 PN++KL ++ + LYLVFE++ DL +A GI +K Y+ QLL G Sbjct: 61 PNIVKLLDVI--HTENKLYLVFEFLHQDLKKFMDASALTGIPL--PLIKSYLFQLLQG 114
>CDK2_CARAU (P43450) Cell division protein kinase 2 (EC 2.7.11.22)| Length = 298 Score = 80.9 bits (198), Expect = 2e-15 Identities = 48/116 (41%), Positives = 73/116 (62%), Gaps = 2/116 (1%) Frame = +2 Query: 218 ESFEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRFMA-REIHILRRLDN 394 ESF+K++KIG+GTY VYKA++ G+ VALKK+R + + E V A REI +L+ L++ Sbjct: 2 ESFQKVEKIGEGTYGVVYKAKNKVTGETVALKKIRL-DTETEGVPSTAIREISLLKELNH 60 Query: 395 PNVIKLEGLVTSRMSSSLYLVFEYMEHDLAGLAATPGIK-FTEAQVKCYMQQLLSG 559 PN++KL ++ + LYLVFE++ DL + + + VK Y+ QLL G Sbjct: 61 PNIVKLHDVI--HTENKLYLVFEFLHQDLKRFMDSSTVTGISLPLVKSYLFQLLQG 114
>CDK2_CRIGR (O55076) Cell division protein kinase 2 (EC 2.7.11.22)| Length = 298 Score = 80.5 bits (197), Expect = 3e-15 Identities = 49/118 (41%), Positives = 75/118 (63%), Gaps = 4/118 (3%) Frame = +2 Query: 218 ESFEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRFMA-REIHILRRLDN 394 E+F+K++KIG+GTY VYKA++ G++VALKK+R + + E V A REI +L+ L++ Sbjct: 2 ENFQKVEKIGEGTYGVVYKAKNKLTGEVVALKKIRL-DTETEGVPSTAIREISLLKELNH 60 Query: 395 PNVIKLEGLVTSRMSSSLYLVFEYMEHDL---AGLAATPGIKFTEAQVKCYMQQLLSG 559 PN++KL ++ + LYLVFE++ DL +A GI +K Y+ QLL G Sbjct: 61 PNIVKLLDVI--HTENKLYLVFEFLHQDLKKFMDASAVTGIPL--PLIKSYLFQLLQG 114
>CDC2H_DICDI (P34117) CDC2-like serine/threonine-protein kinase CRP (EC| 2.7.11.22) (EC 2.7.11.23) Length = 292 Score = 80.5 bits (197), Expect = 3e-15 Identities = 42/114 (36%), Positives = 68/114 (59%) Frame = +2 Query: 218 ESFEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRFMAREIHILRRLDNP 397 E + K++K+G+GTY V KA++ E G+IVALK++R + D REI +L+ L +P Sbjct: 2 EKYSKIEKLGEGTYGIVNKAKNRETGEIVALKRIRLDSEDEGVPCTAIREISLLKELKHP 61 Query: 398 NVIKLEGLVTSRMSSSLYLVFEYMEHDLAGLAATPGIKFTEAQVKCYMQQLLSG 559 N+++L ++ L LVFEY++ DL G + ++ +K +M QLL G Sbjct: 62 NIVRLHDVI--HTERKLTLVFEYLDQDLKKYLDECGGEISKPTIKSFMYQLLKG 113
>CDK2_MOUSE (P97377) Cell division protein kinase 2 (EC 2.7.11.22)| Length = 346 Score = 80.1 bits (196), Expect = 4e-15 Identities = 49/118 (41%), Positives = 75/118 (63%), Gaps = 4/118 (3%) Frame = +2 Query: 218 ESFEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRFMA-REIHILRRLDN 394 E+F+K++KIG+GTY VYKA++ G++VALKK+R + + E V A REI +L+ L++ Sbjct: 2 ENFQKVEKIGEGTYGVVYKAKNKLTGEVVALKKIRL-DTETEGVPSTAIREISLLKELNH 60 Query: 395 PNVIKLEGLVTSRMSSSLYLVFEYMEHDL---AGLAATPGIKFTEAQVKCYMQQLLSG 559 PN++KL ++ + LYLVFE++ DL +A GI +K Y+ QLL G Sbjct: 61 PNIVKLLDVI--HTENKLYLVFEFLHQDLKKFMDASALTGIPL--PLIKSYLFQLLQG 114
>CDK2_BOVIN (Q5E9Y0) Cell division protein kinase 2 (EC 2.7.11.22)| Length = 298 Score = 80.1 bits (196), Expect = 4e-15 Identities = 49/118 (41%), Positives = 75/118 (63%), Gaps = 4/118 (3%) Frame = +2 Query: 218 ESFEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRFMA-REIHILRRLDN 394 E+F+K++KIG+GTY VYKA++ G++VALKK+R + + E V A REI +L+ L++ Sbjct: 2 ENFQKVEKIGEGTYGVVYKAKNKLTGEVVALKKIRL-DTETEGVPSTAIREISLLKELNH 60 Query: 395 PNVIKLEGLVTSRMSSSLYLVFEYMEHDL---AGLAATPGIKFTEAQVKCYMQQLLSG 559 PN++KL ++ + LYLVFE++ DL +A GI +K Y+ QLL G Sbjct: 61 PNIVKLLDVI--HTENKLYLVFEFLHQDLKKFMDASALTGIPL--PLIKSYLFQLLQG 114
>CDC2_HUMAN (P06493) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1) Length = 297 Score = 79.3 bits (194), Expect = 7e-15 Identities = 42/116 (36%), Positives = 67/116 (57%), Gaps = 2/116 (1%) Frame = +2 Query: 218 ESFEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRFMAREIHILRRLDNP 397 E + K++KIG+GTY VYK R G++VA+KK+R + + REI +L+ L +P Sbjct: 2 EDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRHP 61 Query: 398 NVIKLEGLVTSRMSSSLYLVFEYMEHDLAGL--AATPGIKFTEAQVKCYMQQLLSG 559 N++ L+ ++ S LYL+FE++ DL + PG + VK Y+ Q+L G Sbjct: 62 NIVSLQDVL--MQDSRLYLIFEFLSMDLKKYLDSIPPGQYMDSSLVKSYLYQILQG 115
>CDK2_RAT (Q63699) Cell division protein kinase 2 (EC 2.7.11.22)| Length = 298 Score = 79.3 bits (194), Expect = 7e-15 Identities = 48/118 (40%), Positives = 75/118 (63%), Gaps = 4/118 (3%) Frame = +2 Query: 218 ESFEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRFMA-REIHILRRLDN 394 E+F+K++KIG+GTY VYKA++ G++VALKK+R + + E V A REI +L+ L++ Sbjct: 2 ENFQKVEKIGEGTYGVVYKAKNKLTGEVVALKKIRL-DTETEGVPSTAIREISLLKELNH 60 Query: 395 PNVIKLEGLVTSRMSSSLYLVFEYMEHDL---AGLAATPGIKFTEAQVKCYMQQLLSG 559 PN++KL ++ + LYLVFE++ DL +A G+ +K Y+ QLL G Sbjct: 61 PNIVKLLDVI--HTENKLYLVFEFLHQDLKKFMDASALTGLPL--PLIKSYLFQLLQG 114
>CDC2_BOVIN (P48734) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1) Length = 297 Score = 79.0 bits (193), Expect = 9e-15 Identities = 42/116 (36%), Positives = 67/116 (57%), Gaps = 2/116 (1%) Frame = +2 Query: 218 ESFEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRFMAREIHILRRLDNP 397 E + K++KIG+GTY VYK R G++VA+KK+R + + REI +L+ L +P Sbjct: 2 EDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRHP 61 Query: 398 NVIKLEGLVTSRMSSSLYLVFEYMEHDLAGL--AATPGIKFTEAQVKCYMQQLLSG 559 N++ L+ ++ S LYL+FE++ DL + PG + VK Y+ Q+L G Sbjct: 62 NIVSLQDVL--MQDSRLYLIFEFLSMDLKKYLDSIPPGQFMDSSLVKSYLYQILQG 115
>CDC2A_ANTMA (Q38772) Cell division control protein 2 homolog A (EC 2.7.11.22)| (EC 2.7.11.23) Length = 294 Score = 79.0 bits (193), Expect = 9e-15 Identities = 44/115 (38%), Positives = 67/115 (58%), Gaps = 1/115 (0%) Frame = +2 Query: 218 ESFEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRFMAREIHILRRLDNP 397 E +EK++KIG+GTY VYKARD + +ALKK+R D REI +L+ + + Sbjct: 2 EQYEKVEKIGEGTYGVVYKARDRVTNETIALKKIRLEQEDEGVPSTAIREISLLKEMQHG 61 Query: 398 NVIKLEGLVTSRMSSSLYLVFEYMEHDL-AGLAATPGIKFTEAQVKCYMQQLLSG 559 N+++L+ +V S LYLVFEY++ DL + + P VK ++ Q+L G Sbjct: 62 NIVRLQDVVHS--EKRLYLVFEYLDLDLKKHMDSCPEFSQDPRLVKMFLYQILRG 114
>CDK2_MESAU (P48963) Cell division protein kinase 2 (EC 2.7.11.22)| Length = 298 Score = 79.0 bits (193), Expect = 9e-15 Identities = 49/118 (41%), Positives = 74/118 (62%), Gaps = 4/118 (3%) Frame = +2 Query: 218 ESFEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRFMA-REIHILRRLDN 394 E+F+K++KIG+GTY VYKA++ G++VALKK+R + + E V A REI +L+ L++ Sbjct: 2 ENFQKVEKIGEGTYGVVYKAKNKLTGEVVALKKIRL-DTETEGVPSTAIREISLLKELNH 60 Query: 395 PNVIKLEGLVTSRMSSSLYLVFEYMEHDL---AGLAATPGIKFTEAQVKCYMQQLLSG 559 PN++KL ++ + LYLVFE + DL +A GI +K Y+ QLL G Sbjct: 61 PNIVKLLDVI--HTENKLYLVFELLHQDLKKFMDASAVTGIPL--PLIKSYLFQLLQG 114
>CD2L1_RAT (P46892) PITSLRE serine/threonine-protein kinase CDC2L1 (EC| 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 1) Length = 436 Score = 78.6 bits (192), Expect = 1e-14 Identities = 41/117 (35%), Positives = 64/117 (54%) Frame = +2 Query: 209 RKAESFEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRFMAREIHILRRL 388 R E F+ L++I +GTY VY+A+D + +IVALK+++ REI+ + + Sbjct: 74 RSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPLTSIREINTILKA 133 Query: 389 DNPNVIKLEGLVTSRMSSSLYLVFEYMEHDLAGLAATPGIKFTEAQVKCYMQQLLSG 559 +PN++ + +V +Y+V Y+EHDL L T F +VK M QLLSG Sbjct: 134 QHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLSG 190
>CD2L7_CAEEL (P46551) Putative cell division cycle 2-related protein kinase 7| (EC 2.7.11.22) Length = 730 Score = 78.6 bits (192), Expect = 1e-14 Identities = 48/129 (37%), Positives = 69/129 (53%), Gaps = 9/129 (6%) Frame = +2 Query: 200 WQPRKAESFEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRFMAREIHIL 379 W + LD+IG+GTY VYKA + G+ VALK+VR N REI IL Sbjct: 303 WYKTNLTHYTMLDQIGEGTYGQVYKAVNNLTGEQVALKRVRLENEKEGFPITAIREIKIL 362 Query: 380 RRLDNPNVIKLEGLV--------TSRMSSSLYLVFEYMEHDLAGLAATPG-IKFTEAQVK 532 R+L + N+++L +V R ++ YLVFEY++HDL GL + + F + Q+ Sbjct: 363 RQLHHKNIVRLMDIVIDDISMDELKRTRANFYLVFEYVDHDLIGLLESKELVDFNKDQIC 422 Query: 533 CYMQQLLSG 559 +QLL G Sbjct: 423 SLFKQLLEG 431
>CDC2_RAT (P39951) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1) Length = 297 Score = 78.6 bits (192), Expect = 1e-14 Identities = 43/116 (37%), Positives = 67/116 (57%), Gaps = 2/116 (1%) Frame = +2 Query: 218 ESFEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRFMAREIHILRRLDNP 397 E + K++KIG+GTY VYK R G+IVA+KK+R + + REI +L+ L +P Sbjct: 2 EDYIKIEKIGEGTYGVVYKGRHRTTGQIVAMKKIRLESEEEGVPSTAIREISLLKELRHP 61 Query: 398 NVIKLEGLVTSRMSSSLYLVFEYMEHDLAGL--AATPGIKFTEAQVKCYMQQLLSG 559 N++ L+ ++ S LYL+FE++ DL + PG + VK Y+ Q+L G Sbjct: 62 NIVSLQDVL--MQDSRLYLIFEFLSMDLKKYLDSIPPGQFMDSSLVKSYLYQILQG 115
>CDC2_MOUSE (P11440) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1) Length = 297 Score = 78.6 bits (192), Expect = 1e-14 Identities = 43/116 (37%), Positives = 67/116 (57%), Gaps = 2/116 (1%) Frame = +2 Query: 218 ESFEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRFMAREIHILRRLDNP 397 E + K++KIG+GTY VYK R G+IVA+KK+R + + REI +L+ L +P Sbjct: 2 EDYIKIEKIGEGTYGVVYKGRHRVTGQIVAMKKIRLESEEEGVPSTAIREISLLKELRHP 61 Query: 398 NVIKLEGLVTSRMSSSLYLVFEYMEHDLAGL--AATPGIKFTEAQVKCYMQQLLSG 559 N++ L+ ++ S LYL+FE++ DL + PG + VK Y+ Q+L G Sbjct: 62 NIVSLQDVL--MQDSRLYLIFEFLSMDLKKYLDSIPPGQFMDSSLVKSYLHQILQG 115
>CDC2_CARAU (P51958) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1) Length = 302 Score = 78.6 bits (192), Expect = 1e-14 Identities = 45/116 (38%), Positives = 69/116 (59%), Gaps = 2/116 (1%) Frame = +2 Query: 218 ESFEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRFMAREIHILRRLDNP 397 + + K++KIG+GTY VYK R+ G++VA+KK+R + + REI +L+ L +P Sbjct: 2 DDYLKIEKIGEGTYGVVYKGRNKTTGQVVAMKKIRLESEEEGVPSTAVREISLLKELQHP 61 Query: 398 NVIKLEGLVTSRMSSSLYLVFEYMEHDLAG-LAATPGIKFTEAQ-VKCYMQQLLSG 559 NV++L L S LYLVFE++ DL L + P +F + VK Y+ Q+L G Sbjct: 62 NVVRL--LDVLMQESKLYLVFEFLSMDLKKYLDSIPSGQFMDPMLVKSYLYQILEG 115
>CD2L1_MOUSE (P24788) PITSLRE serine/threonine-protein kinase CDC2L1 (EC| 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 1) Length = 784 Score = 78.6 bits (192), Expect = 1e-14 Identities = 44/120 (36%), Positives = 68/120 (56%), Gaps = 3/120 (2%) Frame = +2 Query: 209 RKAESFEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRF---MAREIHIL 379 R E F+ L++I +GTY VY+A+D + +IVALK+++ M+ E F REI+ + Sbjct: 422 RSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLK---MEKEKEGFPITSLREINTI 478 Query: 380 RRLDNPNVIKLEGLVTSRMSSSLYLVFEYMEHDLAGLAATPGIKFTEAQVKCYMQQLLSG 559 + +PN++ + +V +Y+V Y+EHDL L T F +VK M QLLSG Sbjct: 479 LKAQHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLSG 538
>CDK7_XENLA (P20911) Cell division protein kinase 7 (EC 2.7.11.22) (EC| 2.7.11.23) (40 kDa protein kinase) (P40 MO15) (CDC2/CDK2,4-activating kinase) Length = 352 Score = 78.2 bits (191), Expect = 1e-14 Identities = 49/128 (38%), Positives = 73/128 (57%), Gaps = 4/128 (3%) Frame = +2 Query: 188 AVRGWQPR-KAESFEKLDKIGQGTYSSVYKARDLENGKIVALKKVRF---ANMDPESVRF 355 A RG R +A+ +EKLD +G+G +++VYKARD +IVA+KK++ A + R Sbjct: 5 AARGVDVRSRAKQYEKLDFLGEGQFATVYKARDKNTDRIVAIKKIKLGHRAEANDGINRT 64 Query: 356 MAREIHILRRLDNPNVIKLEGLVTSRMSSSLYLVFEYMEHDLAGLAATPGIKFTEAQVKC 535 REI +L+ L +PN+I L L S++ LVF++ME DL + + T A +K Sbjct: 65 ALREIKLLQELSHPNIIGL--LDAFGHKSNISLVFDFMETDLEVIIKDTSLVLTPAHIKS 122 Query: 536 YMQQLLSG 559 YM L G Sbjct: 123 YMLMTLQG 130
>CDC22_PEA (P28567) Cell division control protein 2 homolog 2 (EC 2.7.11.22)| (EC 2.7.11.23) (Fragment) Length = 151 Score = 77.8 bits (190), Expect = 2e-14 Identities = 44/100 (44%), Positives = 60/100 (60%), Gaps = 15/100 (15%) Frame = +2 Query: 305 ALKKVRFANMDPESVRFMAREIHILRRLDNPNVIKLEGLVTSRMSS-------------- 442 ALK++R N REI IL++L + NVIKL+ +VTS Sbjct: 1 ALKEIRMDNEREGFPITAIREIKILKKLHHENVIKLKEIVTSPGPEKDDQGRPDGNKYKR 60 Query: 443 -SLYLVFEYMEHDLAGLAATPGIKFTEAQVKCYMQQLLSG 559 ++Y+VFEYM+HDL GLA PG++FT Q+KCYM+QLL+G Sbjct: 61 LAIYMVFEYMDHDLTGLADRPGMRFTVPQIKCYMRQLLTG 100
>CDC2_PONPY (Q5RCH1) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1) Length = 297 Score = 77.8 bits (190), Expect = 2e-14 Identities = 41/116 (35%), Positives = 66/116 (56%), Gaps = 2/116 (1%) Frame = +2 Query: 218 ESFEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRFMAREIHILRRLDNP 397 E + K++KIG+GTY VYK R G++V +KK+R + + REI +L+ L +P Sbjct: 2 EDYTKIEKIGEGTYGVVYKGRHKTTGQVVTMKKIRLESEEEGVPSTAIREISLLKELRHP 61 Query: 398 NVIKLEGLVTSRMSSSLYLVFEYMEHDLAGL--AATPGIKFTEAQVKCYMQQLLSG 559 N++ L+ ++ S LYL+FE++ DL + PG + VK Y+ Q+L G Sbjct: 62 NIVSLQDVL--MQDSRLYLIFEFLSMDLKKYLDSIPPGQYMDSSLVKSYLYQILQG 115
>CDC2_CHERU (P93101) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34cdc2) Length = 294 Score = 77.4 bits (189), Expect = 3e-14 Identities = 42/115 (36%), Positives = 67/115 (58%), Gaps = 1/115 (0%) Frame = +2 Query: 218 ESFEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRFMAREIHILRRLDNP 397 + +EK++KIG+GTY VYKARD + +ALKK+R D REI +L+ + + Sbjct: 2 DQYEKVEKIGEGTYGVVYKARDKVTNETIALKKIRLEQEDEGVPSTAIREISLLKEMQHG 61 Query: 398 NVIKLEGLVTSRMSSSLYLVFEYMEHDL-AGLAATPGIKFTEAQVKCYMQQLLSG 559 N+++L+ +V S LYLVFEY++ DL + + P +K ++ Q+L G Sbjct: 62 NIVRLQDVVHS--EKRLYLVFEYLDLDLKKHMDSCPDFAKDPRMIKRFLYQILRG 114
>CDC2_MAIZE (P23111) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34cdc2) Length = 294 Score = 77.0 bits (188), Expect = 3e-14 Identities = 42/115 (36%), Positives = 66/115 (57%), Gaps = 1/115 (0%) Frame = +2 Query: 218 ESFEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRFMAREIHILRRLDNP 397 E +EK++KIG+GTY VYKA D + +ALKK+R D REI +L+ +++ Sbjct: 2 EQYEKVEKIGEGTYGVVYKALDKATNETIALKKIRLEQEDEGVPSTAIREISLLKEMNHG 61 Query: 398 NVIKLEGLVTSRMSSSLYLVFEYMEHDLAG-LAATPGIKFTEAQVKCYMQQLLSG 559 N+++L +V S +YLVFEY++ DL + + P +K Y+ Q+L G Sbjct: 62 NIVRLHDVVHS--EKRIYLVFEYLDLDLKKFMDSCPEFAKNPTLIKSYLYQILHG 114
>CDC2_ORYLU (Q9DG98) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1) Length = 303 Score = 76.6 bits (187), Expect = 4e-14 Identities = 43/116 (37%), Positives = 68/116 (58%), Gaps = 2/116 (1%) Frame = +2 Query: 218 ESFEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRFMAREIHILRRLDNP 397 E + K++KIG+GTY VYK R G++VA+KK+R + + RE+ +L+ L +P Sbjct: 2 EDYVKIEKIGEGTYGVVYKGRHKSTGQVVAMKKIRLESEEEGVPSTAVREVSLLQELKHP 61 Query: 398 NVIKLEGLVTSRMSSSLYLVFEYMEHDLAG-LAATPGIKFTEAQ-VKCYMQQLLSG 559 NV++L L S LYL+FE++ DL L + P ++ + VK Y+ Q+L G Sbjct: 62 NVVRL--LDVLMQESRLYLIFEFLSMDLKKYLDSIPSGQYMDPMLVKSYLYQILEG 115
>CDC2_ORYLA (Q9DGD3) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1) Length = 303 Score = 76.6 bits (187), Expect = 4e-14 Identities = 43/116 (37%), Positives = 68/116 (58%), Gaps = 2/116 (1%) Frame = +2 Query: 218 ESFEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRFMAREIHILRRLDNP 397 E + K++KIG+GTY VYK R G++VA+KK+R + + RE+ +L+ L +P Sbjct: 2 EDYVKIEKIGEGTYGVVYKGRHKSTGQVVAMKKIRLESEEEGVPSTAVREVSLLQELKHP 61 Query: 398 NVIKLEGLVTSRMSSSLYLVFEYMEHDLAG-LAATPGIKFTEAQ-VKCYMQQLLSG 559 NV++L L S LYL+FE++ DL L + P ++ + VK Y+ Q+L G Sbjct: 62 NVVRL--LDVLMQESRLYLIFEFLSMDLKKYLDSIPSGQYMDPMLVKSYLYQILEG 115
>CDC2_ORYJA (Q9DGA2) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1) Length = 303 Score = 76.6 bits (187), Expect = 4e-14 Identities = 43/116 (37%), Positives = 68/116 (58%), Gaps = 2/116 (1%) Frame = +2 Query: 218 ESFEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRFMAREIHILRRLDNP 397 E + K++KIG+GTY VYK R G++VA+KK+R + + RE+ +L+ L +P Sbjct: 2 EDYVKIEKIGEGTYGVVYKGRHKSTGQVVAMKKIRLESEEEGVPSTAVREVSLLQELKHP 61 Query: 398 NVIKLEGLVTSRMSSSLYLVFEYMEHDLAG-LAATPGIKFTEAQ-VKCYMQQLLSG 559 NV++L L S LYL+FE++ DL L + P ++ + VK Y+ Q+L G Sbjct: 62 NVVRL--LDVLMQESRLYLIFEFLSMDLKKYLDSIPSGQYMDPMLVKSYLYQILEG 115
>CDC2_ORYCU (Q9DGA5) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1) Length = 303 Score = 76.6 bits (187), Expect = 4e-14 Identities = 43/116 (37%), Positives = 68/116 (58%), Gaps = 2/116 (1%) Frame = +2 Query: 218 ESFEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRFMAREIHILRRLDNP 397 E + K++KIG+GTY VYK R G++VA+KK+R + + RE+ +L+ L +P Sbjct: 2 EDYVKIEKIGEGTYGVVYKGRHKSTGQVVAMKKIRLESEEEGVPSTAVREVSLLQELKHP 61 Query: 398 NVIKLEGLVTSRMSSSLYLVFEYMEHDLAG-LAATPGIKFTEAQ-VKCYMQQLLSG 559 NV++L L S LYL+FE++ DL L + P ++ + VK Y+ Q+L G Sbjct: 62 NVVRL--LDVLMQESRLYLIFEFLSMDLKKYLDSIPSGQYMDPMLVKSYLYQILEG 115
>CDC2_CHICK (P13863) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1) Length = 303 Score = 76.6 bits (187), Expect = 4e-14 Identities = 41/116 (35%), Positives = 67/116 (57%), Gaps = 2/116 (1%) Frame = +2 Query: 218 ESFEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRFMAREIHILRRLDNP 397 E + K++KIG+GTY VYK R G++VA+KK+R + + REI +L+ L +P Sbjct: 2 EDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELHHP 61 Query: 398 NVIKLEGLVTSRMSSSLYLVFEYMEHDLAGLAAT--PGIKFTEAQVKCYMQQLLSG 559 N++ L+ ++ + LYL+FE++ DL T G ++VK Y+ Q+L G Sbjct: 62 NIVCLQDVL--MQDARLYLIFEFLSMDLKKYLDTIPSGQYLDRSRVKSYLYQILQG 115
>CD2L1_HUMAN (P21127) PITSLRE serine/threonine-protein kinase CDC2L1 (EC| 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 1) (CLK-1) (CDK11) (p58 CLK-1) Length = 795 Score = 76.6 bits (187), Expect = 4e-14 Identities = 43/120 (35%), Positives = 67/120 (55%), Gaps = 3/120 (2%) Frame = +2 Query: 209 RKAESFEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRF---MAREIHIL 379 R E F+ L++I +GTY VY+A+D + +IVALK+++ M+ E F REI+ + Sbjct: 433 RSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLK---MEKEKEGFPITSLREINTI 489 Query: 380 RRLDNPNVIKLEGLVTSRMSSSLYLVFEYMEHDLAGLAATPGIKFTEAQVKCYMQQLLSG 559 + +PN++ + +V +Y+V Y+EHDL L T F +VK M QLL G Sbjct: 490 LKAQHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRG 549
>CD2L2_HUMAN (Q9UQ88) PITSLRE serine/threonine-protein kinase CDC2L2 (EC| 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 2) (CDK11) Length = 780 Score = 76.6 bits (187), Expect = 4e-14 Identities = 43/120 (35%), Positives = 67/120 (55%), Gaps = 3/120 (2%) Frame = +2 Query: 209 RKAESFEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRF---MAREIHIL 379 R E F+ L++I +GTY VY+A+D + +IVALK+++ M+ E F REI+ + Sbjct: 418 RSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLK---MEKEKEGFPITSLREINTI 474 Query: 380 RRLDNPNVIKLEGLVTSRMSSSLYLVFEYMEHDLAGLAATPGIKFTEAQVKCYMQQLLSG 559 + +PN++ + +V +Y+V Y+EHDL L T F +VK M QLL G Sbjct: 475 LKAQHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRG 534
>CDC21_MEDSA (P24923) Cell division control protein 2 homolog 1 (EC 2.7.11.22)| (EC 2.7.11.23) (Fragment) Length = 291 Score = 76.3 bits (186), Expect = 6e-14 Identities = 43/112 (38%), Positives = 66/112 (58%), Gaps = 1/112 (0%) Frame = +2 Query: 227 EKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRFMAREIHILRRLDNPNVI 406 E ++KIG+GTY VYKARD + +ALKK+R D REI +L+ + + N++ Sbjct: 2 ENVEKIGEGTYGVVYKARDRVTNETIALKKIRLEQEDEGVPSTAIREISLLKEMQHRNIV 61 Query: 407 KLEGLVTSRMSSSLYLVFEYMEHDL-AGLAATPGIKFTEAQVKCYMQQLLSG 559 +L+ +V S LYLVFEY++ DL + ++P QVK ++ Q+L G Sbjct: 62 RLQDVVHS--DKRLYLVFEYLDLDLKKHMDSSPEFIKDPRQVKMFLYQMLCG 111
>CDC2_RANDY (Q9W739) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) Length = 302 Score = 76.3 bits (186), Expect = 6e-14 Identities = 45/116 (38%), Positives = 67/116 (57%), Gaps = 2/116 (1%) Frame = +2 Query: 218 ESFEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRFMAREIHILRRLDNP 397 + + K++KIG+GTY VYK G+IVA+KK+R N + REI +L+ L +P Sbjct: 2 DEYAKIEKIGEGTYGVVYKGVHKATGQIVAMKKIRLENEEEGVPSTAIREISLLKELQHP 61 Query: 398 NVIKLEGLVTSRMSSSLYLVFEYMEHDLAG-LAATPGIKFTEAQ-VKCYMQQLLSG 559 N++ L L S LYL+FE++ DL L + P ++ EA VK Y+ Q+L G Sbjct: 62 NIVCL--LDVLMQDSRLYLIFEFLSMDLKKYLDSIPSGQYLEAMLVKSYLYQILQG 115
>CDC21_XENLA (P35567) Cell division control protein 2 homolog 1 (EC 2.7.11.22)| (EC 2.7.11.23) (p34 protein kinase 1) Length = 302 Score = 76.3 bits (186), Expect = 6e-14 Identities = 43/116 (37%), Positives = 67/116 (57%), Gaps = 2/116 (1%) Frame = +2 Query: 218 ESFEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRFMAREIHILRRLDNP 397 + + K++KIG+GTY VYK R G++VA+KK+R N + REI +L+ L +P Sbjct: 2 DEYTKIEKIGEGTYGVVYKGRHKATGQVVAMKKIRLENEEEGVPSTAIREISLLKELQHP 61 Query: 398 NVIKLEGLVTSRMSSSLYLVFEYMEHDLAG-LAATPGIKFTEAQ-VKCYMQQLLSG 559 N++ L L S LYL+FE++ DL L + P ++ + VK Y+ Q+L G Sbjct: 62 NIVCL--LDVLMQDSRLYLIFEFLSMDLKKYLDSIPSGQYIDTMLVKSYLYQILQG 115
>CDC2_DICDI (P34112) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) Length = 296 Score = 75.5 bits (184), Expect = 1e-13 Identities = 43/113 (38%), Positives = 69/113 (61%), Gaps = 1/113 (0%) Frame = +2 Query: 224 FEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRFMAREIHILRRLDNPNV 403 ++KL+K+G+GTY VYKA++ G++VALKK+R + S REI +L+ + +PNV Sbjct: 10 YQKLEKLGEGTYGKVYKAKEKATGRMVALKKIRLEDDGVPSTAL--REISLLKEVPHPNV 67 Query: 404 IKLEGLVTSRMSSSLYLVFEYMEHDLAG-LAATPGIKFTEAQVKCYMQQLLSG 559 + L ++ + LYLVFEY++ DL + + P + +K Y+ QLL G Sbjct: 68 VSLFDVL--HCQNRLYLVFEYLDQDLKKYMDSVPAL--CPQLIKSYLYQLLKG 116
>CTK1_YEAST (Q03957) CTD kinase subunit alpha (EC 2.7.11.23) (CTD kinase 58 kDa| subunit) (CTDK-I alpha subunit) Length = 528 Score = 75.5 bits (184), Expect = 1e-13 Identities = 39/119 (32%), Positives = 68/119 (57%) Frame = +2 Query: 203 QPRKAESFEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRFMAREIHILR 382 Q R + ++ ++G+GTY VYKA++ K+VALKK+R REI +L+ Sbjct: 176 QQRSTSVYLRIMQVGEGTYGKVYKAKNTNTEKLVALKKLRLQGEREGFPITSIREIKLLQ 235 Query: 383 RLDNPNVIKLEGLVTSRMSSSLYLVFEYMEHDLAGLAATPGIKFTEAQVKCYMQQLLSG 559 D+PNV ++ ++ ++Y++FEY ++DL+GL ++ + +Q K +QLL G Sbjct: 236 SFDHPNVSTIKEIMV-ESQKTVYMIFEYADNDLSGLLLNKEVQISHSQCKHLFKQLLLG 293
>CDC21_ORYSA (P29618) Cell division control protein 2 homolog 1 (EC 2.7.11.22)| Length = 294 Score = 75.5 bits (184), Expect = 1e-13 Identities = 41/115 (35%), Positives = 65/115 (56%), Gaps = 1/115 (0%) Frame = +2 Query: 218 ESFEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRFMAREIHILRRLDNP 397 E +EK +KIG+GTY VY+ARD + +ALKK+R D REI +L+ + + Sbjct: 2 EQYEKEEKIGEGTYGVVYRARDKVTNETIALKKIRLEQEDEGVPSTAIREISLLKEMHHG 61 Query: 398 NVIKLEGLVTSRMSSSLYLVFEYMEHDLAG-LAATPGIKFTEAQVKCYMQQLLSG 559 N+++L ++ S +YLVFEY++ DL + + P +K Y+ Q+L G Sbjct: 62 NIVRLHDVIHS--EKRIYLVFEYLDLDLKKFMDSCPEFAKNPTLIKSYLYQILRG 114
>BUR1_CANAL (Q9Y7W4) Serine/threonine-protein kinase BUR1 (EC 2.7.11.22) (EC| 2.7.11.23) Length = 746 Score = 75.5 bits (184), Expect = 1e-13 Identities = 42/127 (33%), Positives = 68/127 (53%), Gaps = 11/127 (8%) Frame = +2 Query: 212 KAESFEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRFMAREIHILRRLD 391 + + +E ++K+GQGT+ V KA+ ++G +VA+K++ + REI IL++L+ Sbjct: 40 RLKDYEVIEKLGQGTFGVVQKAKSKKDGSLVAIKQLINHSAKEGFPITAMREITILKQLN 99 Query: 392 NPNVIKLEGLVTSR-----------MSSSLYLVFEYMEHDLAGLAATPGIKFTEAQVKCY 538 + N++ ++ ++ M S Y V YM DL GL P IK Q+KC Sbjct: 100 HKNILTIQDMIFEEPKMSNRTDIITMRGSFYTVTPYMSSDLVGLLENPKIKLELGQIKCI 159 Query: 539 MQQLLSG 559 MQQLL G Sbjct: 160 MQQLLKG 166
>CDC2_AJECA (P54119) Cell division control protein 2 (EC 2.7.11.22) (EC| 2.7.11.23) (Cyclin-dependent protein kinase) Length = 324 Score = 75.5 bits (184), Expect = 1e-13 Identities = 50/135 (37%), Positives = 74/135 (54%), Gaps = 21/135 (15%) Frame = +2 Query: 218 ESFEKLDKIGQGTYSSVYKARDLEN-GKIVALKKVRFANMDPESVRFMAREIHILRRLDN 394 E+++K++KIG+GTY VYKARDL + +IVALKK+R D REI +L+ + + Sbjct: 2 ENYQKIEKIGEGTYGVVYKARDLTHPNRIVALKKIRLEAEDEGVPSTAIREISLLKEMHD 61 Query: 395 PNVIKLEGLVTSRMSSSLYLVFEYMEHDL-------------AGLAATPG-------IKF 514 PN+++L +V + LYLVFE+++ DL G A G + Sbjct: 62 PNIVRLLNIVHAD-GHKLYLVFEFLDLDLKKYMEALPVSEGGRGKALPDGSTLDMNRLGL 120 Query: 515 TEAQVKCYMQQLLSG 559 EA VK +M QL+ G Sbjct: 121 GEAMVKKFMAQLVEG 135
>CDC22_XENLA (P24033) Cell division control protein 2 homolog 2 (EC 2.7.11.22)| (EC 2.7.11.23) (p34 protein kinase 2) Length = 302 Score = 75.1 bits (183), Expect = 1e-13 Identities = 42/116 (36%), Positives = 67/116 (57%), Gaps = 2/116 (1%) Frame = +2 Query: 218 ESFEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRFMAREIHILRRLDNP 397 + + K++KIG+GTY VYK R G++VA+KK+R N + REI +L+ L +P Sbjct: 2 DEYTKIEKIGEGTYGVVYKGRHKATGQVVAMKKIRLENEEEGVPSTAIREISLLKELQHP 61 Query: 398 NVIKLEGLVTSRMSSSLYLVFEYMEHDLAG-LAATPGIKFTEAQ-VKCYMQQLLSG 559 N++ L L S LYL+FE++ D+ L + P ++ + VK Y+ Q+L G Sbjct: 62 NIVCL--LDVLMQDSRLYLIFEFLSMDVKKYLDSIPSGQYIDTMLVKSYLYQILQG 115
>CDK7_MOUSE (Q03147) Cell division protein kinase 7 (EC 2.7.11.22) (EC| 2.7.11.23) (CDK-activating kinase) (CAK) (TFIIH basal transcription factor complex kinase subunit) (39 kDa protein kinase) (P39 Mo15) (Protein-tyrosine kinase MPK-7) (CR4 protein kinas Length = 346 Score = 75.1 bits (183), Expect = 1e-13 Identities = 43/119 (36%), Positives = 68/119 (57%), Gaps = 3/119 (2%) Frame = +2 Query: 212 KAESFEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPES---VRFMAREIHILR 382 +A+ +EKLD +G+G +++VYKARD +IVA+KK++ + R REI +L+ Sbjct: 8 RAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQ 67 Query: 383 RLDNPNVIKLEGLVTSRMSSSLYLVFEYMEHDLAGLAATPGIKFTEAQVKCYMQQLLSG 559 L +PN+I L L S++ LVF++ME DL + + T + +K YM L G Sbjct: 68 ELSHPNIIGL--LDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQG 124
>CDK7_HUMAN (P50613) Cell division protein kinase 7 (EC 2.7.11.22) (EC| 2.7.11.23) (CDK-activating kinase) (CAK) (TFIIH basal transcription factor complex kinase subunit) (39 kDa protein kinase) (P39 Mo15) (STK1) (CAK1) Length = 346 Score = 75.1 bits (183), Expect = 1e-13 Identities = 43/119 (36%), Positives = 68/119 (57%), Gaps = 3/119 (2%) Frame = +2 Query: 212 KAESFEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPES---VRFMAREIHILR 382 +A+ +EKLD +G+G +++VYKARD +IVA+KK++ + R REI +L+ Sbjct: 8 RAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQ 67 Query: 383 RLDNPNVIKLEGLVTSRMSSSLYLVFEYMEHDLAGLAATPGIKFTEAQVKCYMQQLLSG 559 L +PN+I L L S++ LVF++ME DL + + T + +K YM L G Sbjct: 68 ELSHPNIIGL--LDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQG 124
>CDC2_EMENI (Q00646) Cell division control protein 2 (EC 2.7.11.22) (EC| 2.7.11.23) (Cyclin-dependent protein kinase) Length = 323 Score = 75.1 bits (183), Expect = 1e-13 Identities = 46/134 (34%), Positives = 74/134 (55%), Gaps = 20/134 (14%) Frame = +2 Query: 218 ESFEKLDKIGQGTYSSVYKARDLEN-GKIVALKKVRFANMDPESVRFMAREIHILRRLDN 394 E+++K++KIG+GTY VYKAR+L + +IVALKK+R D REI +L+ +++ Sbjct: 2 ENYQKIEKIGEGTYGVVYKARELTHPNRIVALKKIRLEAEDEGVPSTAIREISLLKEMND 61 Query: 395 PNVIKLEGLVTSRMSSSLYLVFEYMEHDLA-------------------GLAATPGIKFT 517 PN+++L +V + LYLVFE+++ DL G + + Sbjct: 62 PNIVRLLNIVHAD-GHKLYLVFEFLDLDLKKYMEALPVSEGGRGRALPDGSTLSRNLGLG 120 Query: 518 EAQVKCYMQQLLSG 559 +A VK +M QL+ G Sbjct: 121 DAMVKKFMAQLIEG 134
>CDC2_DROME (P23572) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) Length = 297 Score = 74.7 bits (182), Expect = 2e-13 Identities = 43/115 (37%), Positives = 70/115 (60%), Gaps = 2/115 (1%) Frame = +2 Query: 218 ESFEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRFMAREIHILRRLDNP 397 E FEK++KIG+GTY VYK R+ G+IVA+KK+R + D REI +L+ L + Sbjct: 2 EDFEKIEKIGEGTYGVVYKGRNRLTGQIVAMKKIRLESDDEGVPSTAIREISLLKELKHE 61 Query: 398 NVIKLEGLVTSRMSSSLYLVFEYMEHDLAG-LAATPGIKFTEAQ-VKCYMQQLLS 556 N++ LE ++ + +YL+FE++ DL + + P K E++ V+ Y+ Q+ S Sbjct: 62 NIVCLEDVLME--ENRIYLIFEFLSMDLKKYMDSLPVDKHMESELVRSYLYQITS 114
>PEF1_SCHPO (O74456) Serine/threonine-protein kinase pef1 (EC 2.7.11.22)| (Cyclin-dependent kinase pef1) (PHO85 homolog) Length = 288 Score = 74.7 bits (182), Expect = 2e-13 Identities = 44/115 (38%), Positives = 71/115 (61%), Gaps = 2/115 (1%) Frame = +2 Query: 221 SFEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRFMAREIHILRRLDNPN 400 ++++L+K+G+GTY+ VYK ++ G+IVALK +R + D + REI +++ L +PN Sbjct: 2 NYQRLEKLGEGTYAHVYKGQNRVTGEIVALKVIRI-DADEGTPSTAIREISLMKELRHPN 60 Query: 401 VIKLEGLVTSRMSSSLYLVFEYMEHDLAGLAATPGIK--FTEAQVKCYMQQLLSG 559 ++ L ++ + + L LVFEYME DL T G + +QVK + QQLL G Sbjct: 61 IMSLSDVL--QTENKLMLVFEYMEKDLKKYMDTYGNQGALPPSQVKNFTQQLLKG 113
>KC47_ORYSA (P29620) CDC2+/CDC28-related protein kinase R2 (EC 2.7.11.22)| Length = 424 Score = 74.3 bits (181), Expect = 2e-13 Identities = 45/118 (38%), Positives = 67/118 (56%), Gaps = 1/118 (0%) Frame = +2 Query: 209 RKAESFEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRFMA-REIHILRR 385 R A+ + K + +G+GTY V+KA D + G VA+KK+R E V F A REI +L+ Sbjct: 14 RVADRYLKREVLGEGTYGVVFKAVDTKTGNTVAIKKIRLGKY-KEGVNFTALREIKLLKE 72 Query: 386 LDNPNVIKLEGLVTSRMSSSLYLVFEYMEHDLAGLAATPGIKFTEAQVKCYMQQLLSG 559 L + N+I+L + +L+LVFE+ME DL + I + A K Y+Q +L G Sbjct: 73 LKDSNIIEL--IDAFPYKGNLHLVFEFMETDLEAVIRDRNIVLSPADTKSYIQMMLKG 128
>PHO85_YARLI (Q6C7U8) Negative regulator of the PHO system (EC 2.7.11.22)| (Serine/threonine-protein kinase PHO85) Length = 294 Score = 73.9 bits (180), Expect = 3e-13 Identities = 45/119 (37%), Positives = 71/119 (59%), Gaps = 4/119 (3%) Frame = +2 Query: 215 AESFEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPE--SVRFMAREIHILRRL 388 + F++L+K+G+GTY++VYK R+ G++VALK++ N+D E + REI +++ L Sbjct: 4 SSQFQQLEKLGEGTYATVYKGRNRTTGQLVALKEI---NLDSEEGTPSTAIREISLMKEL 60 Query: 389 DNPNVIKLEGLVTSRMSSSLYLVFEYMEHDLAGLAATPGIK--FTEAQVKCYMQQLLSG 559 + N++ L ++ + L LVFEYM+ DL T G K QVK +M QLL G Sbjct: 61 KHENIVTLYDVI--HTENKLNLVFEYMDKDLKKFMDTNGNKGALETKQVKWFMYQLLRG 117
>KP58_DROME (Q9VPC0) Serine/threonine-protein kinase PITSLRE (EC 2.7.11.22)| (Cell division cycle 2-like) Length = 952 Score = 73.6 bits (179), Expect = 4e-13 Identities = 43/121 (35%), Positives = 68/121 (56%), Gaps = 6/121 (4%) Frame = +2 Query: 209 RKAESFEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRF---MAREIHIL 379 R E F+ L++I +GTY VY+A+D +IVALK+++ M+ E F REI+ L Sbjct: 553 RSVEEFQCLNRIEEGTYGVVYRAKDKRTNEIVALKRLK---MEKEKEGFPITSLREINTL 609 Query: 380 RRLDNPNVIKLEGLVTSRMSSSLYLVFEYMEHDLAGLAATPGIK---FTEAQVKCYMQQL 550 + +PN++ + +V +++V +Y+EHDL L T + F +VKC QQL Sbjct: 610 LKGQHPNIVTVREIVVGSNMDKIFIVMDYVEHDLKSLMETMKNRKQSFFPGEVKCLTQQL 669 Query: 551 L 553 L Sbjct: 670 L 670
>PFTK1_MOUSE (O35495) Serine/threonine-protein kinase PFTAIRE-1 (EC 2.7.11.22)| Length = 469 Score = 72.8 bits (177), Expect = 6e-13 Identities = 44/117 (37%), Positives = 69/117 (58%), Gaps = 1/117 (0%) Frame = +2 Query: 212 KAESFEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRFMA-REIHILRRL 388 KA+S+EKL+K+G+G+Y++VYK + NGK+VALK +R + E F A RE +L+ L Sbjct: 131 KADSYEKLEKLGEGSYATVYKGKSKVNGKLVALKVIRL--QEEEGTPFTAIREASLLKGL 188 Query: 389 DNPNVIKLEGLVTSRMSSSLYLVFEYMEHDLAGLAATPGIKFTEAQVKCYMQQLLSG 559 + N++ L ++ ++ +L LVFEY+ DL VK ++ QLL G Sbjct: 189 KHANIVLLHDIIHTK--ETLTLVFEYVHTDLCQYMEQHPGGLHPDNVKLFLFQLLRG 243
>PFTK1_HUMAN (O94921) Serine/threonine-protein kinase PFTAIRE-1 (EC 2.7.11.22)| Length = 469 Score = 72.4 bits (176), Expect = 8e-13 Identities = 44/117 (37%), Positives = 69/117 (58%), Gaps = 1/117 (0%) Frame = +2 Query: 212 KAESFEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRFMA-REIHILRRL 388 KA+S+EKL+K+G+G+Y++VYK + NGK+VALK +R + E F A RE +L+ L Sbjct: 131 KADSYEKLEKLGEGSYATVYKGKSKVNGKLVALKVIRL--QEEEGTPFTAIREASLLKGL 188 Query: 389 DNPNVIKLEGLVTSRMSSSLYLVFEYMEHDLAGLAATPGIKFTEAQVKCYMQQLLSG 559 + N++ L ++ ++ +L LVFEY+ DL VK ++ QLL G Sbjct: 189 KHANIVLLHDIIHTK--ETLTLVFEYVHTDLCQYMDKHPGGLHPDNVKLFLFQLLRG 243
>CDC22_ORYSA (P29619) Cell division control protein 2 homolog 2 (EC 2.7.11.22)| Length = 292 Score = 72.4 bits (176), Expect = 8e-13 Identities = 40/115 (34%), Positives = 66/115 (57%), Gaps = 1/115 (0%) Frame = +2 Query: 218 ESFEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRFMAREIHILRRLDNP 397 E +EK++KIG+GTY VYK + + +ALKK+R D REI +L+ + + Sbjct: 2 EQYEKVEKIGEGTYGVVYKGKHRHTNETIALKKIRLEQEDEGVPSTAIREISLLKEMQHR 61 Query: 398 NVIKLEGLVTSRMSSSLYLVFEYMEHDL-AGLAATPGIKFTEAQVKCYMQQLLSG 559 N+++L+ +V +YLVFEY++ DL + ++P K VK ++ Q+L G Sbjct: 62 NIVRLQDVV--HKEKCIYLVFEYLDLDLKKHMDSSPDFK-NHRIVKSFLYQILRG 113
>CDK5_XENLA (P51166) Cell division protein kinase 5 (EC 2.7.11.22) (Neuronal| cyclin-dependent kinase 5) Length = 292 Score = 72.0 bits (175), Expect = 1e-12 Identities = 42/114 (36%), Positives = 66/114 (57%) Frame = +2 Query: 218 ESFEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRFMAREIHILRRLDNP 397 + +EKL+KIG+GTY +V+KA++ + +IVALK+VR + D REI +L+ L + Sbjct: 2 QKYEKLEKIGEGTYGTVFKAKNRDTHEIVALKRVRLDDDDEGVPSSALREICLLKELKHK 61 Query: 398 NVIKLEGLVTSRMSSSLYLVFEYMEHDLAGLAATPGIKFTEAQVKCYMQQLLSG 559 N+++L ++ S L LVFE+ + DL + VK +M QLL G Sbjct: 62 NIVRLHDVLHS--DKKLTLVFEFCDQDLKKYFDSCNGDLDPEIVKSFMYQLLKG 113
>CC2H1_TRYCO (P54664) Cell division control protein 2 homolog 1 (EC 2.7.11.22)| Length = 301 Score = 71.6 bits (174), Expect = 1e-12 Identities = 41/112 (36%), Positives = 64/112 (57%) Frame = +2 Query: 224 FEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRFMAREIHILRRLDNPNV 403 +++L+KIG+G+Y VY+ARD+ IVALK++R +++ REI IL+ L + N+ Sbjct: 5 YQRLEKIGEGSYGVVYRARDITTDVIVALKRIRLESVEEGVPCTAIREISILKELRHENI 64 Query: 404 IKLEGLVTSRMSSSLYLVFEYMEHDLAGLAATPGIKFTEAQVKCYMQQLLSG 559 ++L L + L LVFEYME DL A ++ +M+ LL G Sbjct: 65 VRL--LDVCHSENRLNLVFEYMEMDLKKYMDRASGNLDPATIQEFMRSLLKG 114
>CDK7_RAT (P51952) Cell division protein kinase 7 (EC 2.7.11.22) (EC| 2.7.11.23) (CDK-activating kinase) (CAK) (TFIIH basal transcription factor complex kinase subunit) (39 protein kinase) (P39 Mo15) (Fragment) Length = 329 Score = 71.6 bits (174), Expect = 1e-12 Identities = 42/114 (36%), Positives = 64/114 (56%), Gaps = 3/114 (2%) Frame = +2 Query: 227 EKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPES---VRFMAREIHILRRLDNP 397 EKLD +G+G +++VYKARD +IVA+KK++ + R REI +L+ L +P Sbjct: 5 EKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHP 64 Query: 398 NVIKLEGLVTSRMSSSLYLVFEYMEHDLAGLAATPGIKFTEAQVKCYMQQLLSG 559 N+I L L S++ LVF++ME DL + + T + +K YM L G Sbjct: 65 NIIGL--LDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQG 116
>CDC28_CANAL (P43063) Cell division control protein 28 (EC 2.7.11.22)| Length = 317 Score = 71.2 bits (173), Expect = 2e-12 Identities = 40/115 (34%), Positives = 68/115 (59%), Gaps = 3/115 (2%) Frame = +2 Query: 224 FEKLDKIGQGTYSSVYKARDLE-NGKIVALKKVRFANMDPESVRFMAREIHILRRLDNPN 400 +++ +K+G+GTY VYKA D + N ++VALKK+R + D REI +L+ + + N Sbjct: 7 YQRQEKVGEGTYGVVYKALDTKHNNRVVALKKIRLESEDEGVPSTAIREISLLKEMKDDN 66 Query: 401 VIKLEGLVTSRMSSSLYLVFEYMEHDLAGL--AATPGIKFTEAQVKCYMQQLLSG 559 +++L ++ S S LYLVFE+++ DL + G+ +K +M QL+ G Sbjct: 67 IVRLYDIIHSD-SHKLYLVFEFLDLDLKKYMESIPQGVGLGANMIKRFMNQLIRG 120
>CDKL1_HUMAN (Q00532) Cyclin-dependent kinase-like 1 (EC 2.7.11.22)| (Serine/threonine-protein kinase KKIALRE) (Protein kinase p42 KKIALRE) Length = 357 Score = 71.2 bits (173), Expect = 2e-12 Identities = 36/86 (41%), Positives = 55/86 (63%) Frame = +2 Query: 218 ESFEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRFMAREIHILRRLDNP 397 E +EK+ KIG+G+Y V+K R+ + G+IVA+KK + DP + REI +L++L +P Sbjct: 2 EKYEKIGKIGEGSYGVVFKCRNRDTGQIVAIKKFLESEDDPVIKKIALREIRMLKQLKHP 61 Query: 398 NVIKLEGLVTSRMSSSLYLVFEYMEH 475 N++ L L R L+LVFEY +H Sbjct: 62 NLVNL--LEVFRRKRRLHLVFEYCDH 85
>CDC2H_THEPA (Q27032) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) Length = 298 Score = 71.2 bits (173), Expect = 2e-12 Identities = 45/114 (39%), Positives = 68/114 (59%), Gaps = 2/114 (1%) Frame = +2 Query: 224 FEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRFMAREIHILRRLDNPNV 403 + K++KIG+GTY VYKA++ +G+I ALKK+R D REI +L+ L +PN+ Sbjct: 4 YHKMEKIGEGTYGVVYKAQN-NHGEICALKKIRVEEEDEGIPSTAIREISLLKELHHPNI 62 Query: 404 IKLEGLVTSRMSSSLYLVFEYMEHDLAGL--AATPGIKFTEAQVKCYMQQLLSG 559 + L ++ S L LVFEY++ DL L A G++ T A K ++ Q+L G Sbjct: 63 VWLRDVIHS--EKCLTLVFEYLDQDLKKLLDACDGGLEPTTA--KSFLYQILRG 112
>CDC2H_THEAN (Q26671) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) Length = 298 Score = 71.2 bits (173), Expect = 2e-12 Identities = 45/114 (39%), Positives = 68/114 (59%), Gaps = 2/114 (1%) Frame = +2 Query: 224 FEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRFMAREIHILRRLDNPNV 403 + K++KIG+GTY VYKA++ +G+I ALKK+R D REI +L+ L +PN+ Sbjct: 4 YHKMEKIGEGTYGVVYKAQN-NHGEICALKKIRVEEEDEGIPSTAIREISLLKELHHPNI 62 Query: 404 IKLEGLVTSRMSSSLYLVFEYMEHDLAGL--AATPGIKFTEAQVKCYMQQLLSG 559 + L ++ S L LVFEY++ DL L A G++ T A K ++ Q+L G Sbjct: 63 VWLRDVIHS--EKCLTLVFEYLDQDLKKLLDACDGGLEPTTA--KSFLYQILRG 112
>CDK5_MOUSE (P49615) Cell division protein kinase 5 (EC 2.7.11.22) (Tau protein| kinase II catalytic subunit) (TPKII catalytic subunit) (Serine/threonine-protein kinase PSSALRE) (CRK6) Length = 292 Score = 71.2 bits (173), Expect = 2e-12 Identities = 42/114 (36%), Positives = 66/114 (57%) Frame = +2 Query: 218 ESFEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRFMAREIHILRRLDNP 397 + +EKL+KIG+GTY +V+KA++ E +IVALK+VR + D REI +L+ L + Sbjct: 2 QKYEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELKHK 61 Query: 398 NVIKLEGLVTSRMSSSLYLVFEYMEHDLAGLAATPGIKFTEAQVKCYMQQLLSG 559 N+++L ++ S L LVFE+ + DL + VK ++ QLL G Sbjct: 62 NIVRLHDVLHS--DKKLTLVFEFCDQDLKKYFDSCNGDLDPEIVKSFLFQLLKG 113
>CDK5_HUMAN (Q00535) Cell division protein kinase 5 (EC 2.7.11.22) (Tau protein| kinase II catalytic subunit) (TPKII catalytic subunit) (Serine/threonine-protein kinase PSSALRE) Length = 292 Score = 71.2 bits (173), Expect = 2e-12 Identities = 42/114 (36%), Positives = 66/114 (57%) Frame = +2 Query: 218 ESFEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRFMAREIHILRRLDNP 397 + +EKL+KIG+GTY +V+KA++ E +IVALK+VR + D REI +L+ L + Sbjct: 2 QKYEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELKHK 61 Query: 398 NVIKLEGLVTSRMSSSLYLVFEYMEHDLAGLAATPGIKFTEAQVKCYMQQLLSG 559 N+++L ++ S L LVFE+ + DL + VK ++ QLL G Sbjct: 62 NIVRLHDVLHS--DKKLTLVFEFCDQDLKKYFDSCNGDLDPEIVKSFLFQLLKG 113
>CDK5_BOVIN (Q02399) Cell division protein kinase 5 (EC 2.7.11.22) (Tau protein| kinase II catalytic subunit) (TPKII catalytic subunit) (Proline-directed protein kinase 33 kDa subunit) (PDPK) Length = 292 Score = 71.2 bits (173), Expect = 2e-12 Identities = 42/114 (36%), Positives = 66/114 (57%) Frame = +2 Query: 218 ESFEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRFMAREIHILRRLDNP 397 + +EKL+KIG+GTY +V+KA++ E +IVALK+VR + D REI +L+ L + Sbjct: 2 QKYEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELKHK 61 Query: 398 NVIKLEGLVTSRMSSSLYLVFEYMEHDLAGLAATPGIKFTEAQVKCYMQQLLSG 559 N+++L ++ S L LVFE+ + DL + VK ++ QLL G Sbjct: 62 NIVRLHDVLHS--DKKLTLVFEFCDQDLKKYFDSCNGDLDPEIVKSFLFQLLKG 113
>CC2H2_TRYBB (P54665) Cell division control protein 2 homolog 2 (EC 2.7.11.22)| Length = 345 Score = 70.9 bits (172), Expect = 2e-12 Identities = 38/114 (33%), Positives = 63/114 (55%) Frame = +2 Query: 218 ESFEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRFMAREIHILRRLDNP 397 + + +++K+G+G+Y VYK D G+ VA+K++ D RE+ +LR L++P Sbjct: 44 DRYSRIEKVGEGSYGIVYKCHDNFTGRTVAMKRIPLIVNDGGVPSTAVREVSLLRELNHP 103 Query: 398 NVIKLEGLVTSRMSSSLYLVFEYMEHDLAGLAATPGIKFTEAQVKCYMQQLLSG 559 V++L +V + L L+FEYME DL G+ F +++ M QLL G Sbjct: 104 YVVRLLDVVLH--EAKLLLIFEYMEQDLQGMLKQRNTAFVGGKLRRIMFQLLLG 155
>CDKL1_BRARE (Q6AXJ9) Cyclin-dependent kinase-like 1 (EC 2.7.11.22)| Length = 350 Score = 70.5 bits (171), Expect = 3e-12 Identities = 35/86 (40%), Positives = 55/86 (63%) Frame = +2 Query: 218 ESFEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRFMAREIHILRRLDNP 397 E +EK+ KIG+G+Y V+K R+ + G+IVA+KK + DP + REI +L++L +P Sbjct: 2 EKYEKISKIGEGSYGVVFKCRNKDTGQIVAIKKFVESEDDPIIKKIALREIRMLKQLKHP 61 Query: 398 NVIKLEGLVTSRMSSSLYLVFEYMEH 475 N++ L + R L+LVFEY +H Sbjct: 62 NLVNL--MEVFRRKRKLHLVFEYCDH 85
>PCTK3_PONPY (Q5RD01) Serine/threonine-protein kinase PCTAIRE-3 (EC 2.7.11.22)| (PCTAIRE-motif protein kinase 3) Length = 472 Score = 70.5 bits (171), Expect = 3e-12 Identities = 42/116 (36%), Positives = 66/116 (56%) Frame = +2 Query: 212 KAESFEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRFMAREIHILRRLD 391 K E++ KLDK+G+GTY++V+K R +VALK++R + + + RE+ +L+ L Sbjct: 138 KLETYVKLDKLGEGTYATVFKGRSKLTENLVALKEIRLEHEEGAPCTAI-REVSLLKNLK 196 Query: 392 NPNVIKLEGLVTSRMSSSLYLVFEYMEHDLAGLAATPGIKFTEAQVKCYMQQLLSG 559 + N++ L L+ SL LVFEY++ DL G + VK +M QLL G Sbjct: 197 HANIVTLHDLI--HTDRSLTLVFEYLDSDLKQYLDHCGNLMSMHNVKIFMFQLLRG 250
>CDK4_XENLA (Q91727) Cell division protein kinase 4 (EC 2.7.11.22)| (Cyclin-dependent kinase 4) Length = 319 Score = 70.1 bits (170), Expect = 4e-12 Identities = 45/119 (37%), Positives = 68/119 (57%), Gaps = 7/119 (5%) Frame = +2 Query: 224 FEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRFMAREIHILRRL---DN 394 +E + +IG G Y +VYKARDL++GK VALK VR + RE+ +L+RL D+ Sbjct: 9 YEPVAEIGVGAYGTVYKARDLQSGKFVALKNVRVQTNENGLPLSTVREVTLLKRLEHFDH 68 Query: 395 PNVIKLEGLVTSRMS---SSLYLVFEYMEHDL-AGLAATPGIKFTEAQVKCYMQQLLSG 559 PN++KL + S + + + LVFE+++ DL L+ P +K M+Q LSG Sbjct: 69 PNIVKLMDVCASARTDRETKVTLVFEHVDQDLKTYLSKVPPPGLPLETIKDLMKQFLSG 127
>BUR1_DEBHA (Q6BV06) Serine/threonine-protein kinase BUR1 (EC 2.7.11.22) (EC| 2.7.11.23) Length = 608 Score = 70.1 bits (170), Expect = 4e-12 Identities = 41/127 (32%), Positives = 67/127 (52%), Gaps = 11/127 (8%) Frame = +2 Query: 212 KAESFEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRFMAREIHILRRLD 391 K ++E + K+GQGT+ V KAR+++ ++VALK++ + REI IL++L+ Sbjct: 35 KLRNYEIIQKLGQGTFGVVQKARNIKTKELVALKQLINHSAKEGFPITAMREITILKKLN 94 Query: 392 NPNVIKLEGLVTSRMSSS-----------LYLVFEYMEHDLAGLAATPGIKFTEAQVKCY 538 + N++K+ ++ S Y V YM DL GL P I + +KC+ Sbjct: 95 HKNILKIIDMIYEEPKISNPQDILHQRGCFYTVSPYMCSDLVGLLENPNINLEVSHIKCF 154 Query: 539 MQQLLSG 559 M+QLL G Sbjct: 155 MEQLLHG 161
>CDC2_CAEEL (P34556) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) Length = 332 Score = 69.7 bits (169), Expect = 5e-12 Identities = 34/86 (39%), Positives = 53/86 (61%) Frame = +2 Query: 224 FEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRFMAREIHILRRLDNPNV 403 F KL+KIG+GTY VYK ++ +VA+KK+R + D REI +L+ L +PNV Sbjct: 22 FTKLEKIGEGTYGVVYKGKNRRTNAMVAMKKIRLESEDEGVPSTAVREISLLKELQHPNV 81 Query: 404 IKLEGLVTSRMSSSLYLVFEYMEHDL 481 + LE ++ + L+L+FE++ DL Sbjct: 82 VGLEAVI--MQENRLFLIFEFLSFDL 105
>CDKL1_MOUSE (Q8CEQ0) Cyclin-dependent kinase-like 1 (EC 2.7.11.22)| Length = 352 Score = 69.7 bits (169), Expect = 5e-12 Identities = 35/86 (40%), Positives = 54/86 (62%) Frame = +2 Query: 218 ESFEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRFMAREIHILRRLDNP 397 E +EK+ KIG+G+Y V+K R+ + G+IVA+K+ DP + REI +L++L +P Sbjct: 2 EKYEKIGKIGEGSYGVVFKCRNRDTGQIVAIKRFLETEDDPVIKKIALREIRMLKQLKHP 61 Query: 398 NVIKLEGLVTSRMSSSLYLVFEYMEH 475 N++ L L R L+LVFEY +H Sbjct: 62 NLVNL--LEVFRRKRRLHLVFEYCDH 85
>PCTK3_HUMAN (Q07002) Serine/threonine-protein kinase PCTAIRE-3 (EC 2.7.11.22)| (PCTAIRE-motif protein kinase 3) Length = 472 Score = 69.7 bits (169), Expect = 5e-12 Identities = 42/116 (36%), Positives = 66/116 (56%) Frame = +2 Query: 212 KAESFEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRFMAREIHILRRLD 391 K E++ KLDK+G+GTY++V+K R +VALK++R + + + RE+ +L+ L Sbjct: 138 KLETYVKLDKLGEGTYATVFKGRSKLMENLVALKEIRLEHEEGAPCTAI-REVSLLKNLK 196 Query: 392 NPNVIKLEGLVTSRMSSSLYLVFEYMEHDLAGLAATPGIKFTEAQVKCYMQQLLSG 559 + N++ L L+ SL LVFEY++ DL G + VK +M QLL G Sbjct: 197 HANIVTLHDLI--HTDRSLTLVFEYLDSDLKQYLDHCGNLMSMHNVKIFMFQLLRG 250
>CDK5_RAT (Q03114) Cell division protein kinase 5 (EC 2.7.11.22) (Tau protein| kinase II catalytic subunit) (TPKII catalytic subunit) (Serine/threonine-protein kinase PSSALRE) Length = 292 Score = 69.7 bits (169), Expect = 5e-12 Identities = 42/114 (36%), Positives = 65/114 (57%) Frame = +2 Query: 218 ESFEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRFMAREIHILRRLDNP 397 + +EKL+KIG+GTY +V+KA++ E +IVALK+VR + D REI +L+ L + Sbjct: 2 QKYEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELKHK 61 Query: 398 NVIKLEGLVTSRMSSSLYLVFEYMEHDLAGLAATPGIKFTEAQVKCYMQQLLSG 559 N+++L ++ S L LVFE+ + DL + VK + QLL G Sbjct: 62 NIVRLHDVLHS--DKKLTLVFEFCDQDLKKYFDSCNGDLDPEIVKSLLFQLLKG 113
>PCTK3_RAT (O35832) Serine/threonine-protein kinase PCTAIRE-3 (EC 2.7.11.22)| (PCTAIRE-motif protein kinase 3) Length = 451 Score = 69.3 bits (168), Expect = 7e-12 Identities = 42/116 (36%), Positives = 65/116 (56%) Frame = +2 Query: 212 KAESFEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRFMAREIHILRRLD 391 K E++ KLDK+G+GTY++V+K R +VALK++R + + + RE+ +L+ L Sbjct: 117 KLETYVKLDKLGEGTYATVFKGRSKLTENLVALKEIRLEHEEGAPCTAI-REVSLLKDLK 175 Query: 392 NPNVIKLEGLVTSRMSSSLYLVFEYMEHDLAGLAATPGIKFTEAQVKCYMQQLLSG 559 + N++ L L+ SL LVFEY++ DL G VK +M QLL G Sbjct: 176 HANIVTLHDLI--HTDRSLTLVFEYLDSDLKQYLDHCGNLMNMHNVKIFMFQLLRG 229
>PCTK3_MOUSE (Q04899) Serine/threonine-protein kinase PCTAIRE-3 (EC 2.7.11.22)| (PCTAIRE-motif protein kinase 3) Length = 451 Score = 69.3 bits (168), Expect = 7e-12 Identities = 42/116 (36%), Positives = 65/116 (56%) Frame = +2 Query: 212 KAESFEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRFMAREIHILRRLD 391 K E++ KLDK+G+GTY++V+K R +VALK++R + + + RE+ +L+ L Sbjct: 117 KLETYVKLDKLGEGTYATVFKGRSKLTENLVALKEIRLEHEEGAPCTAI-REVSLLKDLK 175 Query: 392 NPNVIKLEGLVTSRMSSSLYLVFEYMEHDLAGLAATPGIKFTEAQVKCYMQQLLSG 559 + N++ L L+ SL LVFEY++ DL G VK +M QLL G Sbjct: 176 HANIVTLHDLI--HTDRSLTLVFEYLDSDLKQYLDHCGNLMNMHNVKIFMFQLLRG 229
>MHK_ARATH (P43294) Serine/threonine-protein kinase MHK (EC 2.7.11.22)| Length = 443 Score = 69.3 bits (168), Expect = 7e-12 Identities = 39/112 (34%), Positives = 70/112 (62%) Frame = +2 Query: 224 FEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRFMAREIHILRRLDNPNV 403 ++ L+++G GT SVYKA +LE ++VA+KK++ E RE+ LR+L++P++ Sbjct: 12 YKILEELGDGTCGSVYKAVNLETYEVVAVKKMKRKFYYWEEC-VNLREVKALRKLNHPHI 70 Query: 404 IKLEGLVTSRMSSSLYLVFEYMEHDLAGLAATPGIKFTEAQVKCYMQQLLSG 559 IKL+ +V R + L+ +FE M+H+L + F+E +++ +M Q+L G Sbjct: 71 IKLKEIV--REHNELFFIFECMDHNLYHIMKERERPFSEGEIRSFMSQMLQG 120
>CDC28_YEAST (P00546) Cell division control protein 28 (EC 2.7.11.22)| Length = 298 Score = 69.3 bits (168), Expect = 7e-12 Identities = 45/118 (38%), Positives = 70/118 (59%), Gaps = 5/118 (4%) Frame = +2 Query: 221 SFEKLDKIGQGTYSSVYKARDLENG---KIVALKKVRFANMDPESVRFMAREIHILRRLD 391 ++++L+K+G+GTY VYKA DL G ++VALKK+R + D REI +L+ L Sbjct: 7 NYKRLEKVGEGTYGVVYKALDLRPGQGQRVVALKKIRLESEDEGVPSTAIREISLLKELK 66 Query: 392 NPNVIKLEGLVTSRMSSSLYLVFEYMEHDLAG-LAATPGIKFTEAQ-VKCYMQQLLSG 559 + N+++L +V S + LYLVFE+++ DL + P + A VK +M QL G Sbjct: 67 DDNIVRLYDIVHSD-AHKLYLVFEFLDLDLKRYMEGIPKDQPLGADIVKKFMMQLCKG 123
>CDC2D_ANTMA (Q38775) Cell division control protein 2 homolog D (EC 2.7.11.22)| (EC 2.7.11.23) Length = 312 Score = 68.9 bits (167), Expect = 9e-12 Identities = 45/121 (37%), Positives = 63/121 (52%), Gaps = 7/121 (5%) Frame = +2 Query: 218 ESFEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRFMAREIHILRRLD-N 394 ++F KL+K+G+GTY VY+A + GKIVALKK R + RE+ +LR L + Sbjct: 12 DAFVKLEKVGEGTYGKVYRAMEKSTGKIVALKKTRLHEDEEGVPPTTLREVSLLRMLSRD 71 Query: 395 PNVIKLEGLVTSRMSSS---LYLVFEYMEHDLAGLAAT---PGIKFTEAQVKCYMQQLLS 556 P+V++L + + LYLVFEYM+ DL + G VK M QL Sbjct: 72 PHVVRLLDVKQGQNKEGKTVLYLVFEYMDTDLKKYIRSFKQTGESIAPMNVKSLMYQLCK 131 Query: 557 G 559 G Sbjct: 132 G 132
>CDKL1_RAT (Q66HE7) Cyclin-dependent kinase-like 1 (EC 2.7.11.22)| Length = 352 Score = 68.9 bits (167), Expect = 9e-12 Identities = 35/86 (40%), Positives = 53/86 (61%) Frame = +2 Query: 218 ESFEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRFMAREIHILRRLDNP 397 E +EK+ KIG+G+Y V+K R+ + G+IVA+K+ DP + REI +L++L +P Sbjct: 2 EKYEKIGKIGEGSYGVVFKCRNRDTGQIVAIKRFLETEDDPVIKKIALREIRMLKQLKHP 61 Query: 398 NVIKLEGLVTSRMSSSLYLVFEYMEH 475 N++ L L R L+LVFEY H Sbjct: 62 NLVSL--LEVFRRKRRLHLVFEYCHH 85
>PHO85_DEBHA (Q6BRY2) Negative regulator of the PHO system (EC 2.7.11.22)| (Serine/threonine-protein kinase PHO85) Length = 330 Score = 68.6 bits (166), Expect = 1e-11 Identities = 42/119 (35%), Positives = 71/119 (59%), Gaps = 4/119 (3%) Frame = +2 Query: 215 AESFEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPE--SVRFMAREIHILRRL 388 + F++L+K+G+GTY++VYK R+ NG++VALK++ N+D E + REI +++ L Sbjct: 5 SSQFQQLEKLGEGTYATVYKGRNRTNGQLVALKEI---NLDSEEGTPSTAIREISLMKEL 61 Query: 389 DNPNVIKLEGLVTSRMSSSLYLVFEYMEHDLAGLAATPGIK--FTEAQVKCYMQQLLSG 559 D+ N++ L ++ + L LVFE+M+ DL G + VK ++ QLL G Sbjct: 62 DHENIVTLYDVI--HTENKLTLVFEFMDKDLKKYMEAHGNQGALDLKIVKSFIFQLLKG 118
>PCTK1_RAT (Q63686) Serine/threonine-protein kinase PCTAIRE-1 (EC 2.7.11.22)| (PCTAIRE-motif protein kinase 1) Length = 496 Score = 68.6 bits (166), Expect = 1e-11 Identities = 40/116 (34%), Positives = 65/116 (56%) Frame = +2 Query: 212 KAESFEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRFMAREIHILRRLD 391 K E++ KLDK+G+GTY++VYK + +VALK++R + + + RE+ +L+ L Sbjct: 161 KLETYIKLDKLGEGTYATVYKGKSKLTDNLVALKEIRLEHEEGAPCTAI-REVSLLKDLK 219 Query: 392 NPNVIKLEGLVTSRMSSSLYLVFEYMEHDLAGLAATPGIKFTEAQVKCYMQQLLSG 559 + N++ L ++ SL LVFEY++ DL G VK ++ QLL G Sbjct: 220 HANIVTLHDII--HTEKSLTLVFEYLDKDLKQYLDDCGNVINMHNVKLFLFQLLRG 273
>PCTK1_MOUSE (Q04735) Serine/threonine-protein kinase PCTAIRE-1 (EC 2.7.11.22)| (PCTAIRE-motif protein kinase 1) (CRK5) Length = 496 Score = 68.6 bits (166), Expect = 1e-11 Identities = 40/116 (34%), Positives = 65/116 (56%) Frame = +2 Query: 212 KAESFEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRFMAREIHILRRLD 391 K E++ KLDK+G+GTY++VYK + +VALK++R + + + RE+ +L+ L Sbjct: 161 KLETYIKLDKLGEGTYATVYKGKSKLTDNLVALKEIRLEHEEGAPCTAI-REVSLLKDLK 219 Query: 392 NPNVIKLEGLVTSRMSSSLYLVFEYMEHDLAGLAATPGIKFTEAQVKCYMQQLLSG 559 + N++ L ++ SL LVFEY++ DL G VK ++ QLL G Sbjct: 220 HANIVTLHDII--HTEKSLTLVFEYLDKDLKQYLDDCGNVINMHNVKLFLFQLLRG 273
>PCTK2_RAT (O35831) Serine/threonine-protein kinase PCTAIRE-2 (EC 2.7.11.22)| (PCTAIRE-motif protein kinase 2) Length = 523 Score = 68.6 bits (166), Expect = 1e-11 Identities = 40/116 (34%), Positives = 66/116 (56%) Frame = +2 Query: 212 KAESFEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRFMAREIHILRRLD 391 K E++ KL+K+G+GTY++VYK R +VALK++R + + + RE+ +L+ L Sbjct: 188 KMETYIKLEKLGEGTYATVYKGRSKLTENLVALKEIRLEHEEGAPCTAI-REVSLLKDLK 246 Query: 392 NPNVIKLEGLVTSRMSSSLYLVFEYMEHDLAGLAATPGIKFTEAQVKCYMQQLLSG 559 + N++ L +V SL LVFEY++ DL G + VK ++ Q+L G Sbjct: 247 HANIVTLHDIV--HTDKSLTLVFEYLDKDLKQYMDDCGSIMSMHNVKLFLYQILRG 300
>PCTK1_HUMAN (Q00536) Serine/threonine-protein kinase PCTAIRE-1 (EC 2.7.11.22)| (PCTAIRE-motif protein kinase 1) Length = 496 Score = 68.2 bits (165), Expect = 2e-11 Identities = 40/116 (34%), Positives = 65/116 (56%) Frame = +2 Query: 212 KAESFEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRFMAREIHILRRLD 391 K E++ KLDK+G+GTY++VYK + +VALK++R + + + RE+ +L+ L Sbjct: 161 KLETYIKLDKLGEGTYATVYKGKSKLTDNLVALKEIRLEHEEGAPCTAI-REVSLLKDLK 219 Query: 392 NPNVIKLEGLVTSRMSSSLYLVFEYMEHDLAGLAATPGIKFTEAQVKCYMQQLLSG 559 + N++ L ++ SL LVFEY++ DL G VK ++ QLL G Sbjct: 220 HANIVTLHDII--HTEKSLTLVFEYLDKDLKQYLDDCGNIINMHNVKLFLFQLLRG 273
>FIN1_SCHPO (O13839) G2-specific protein kinase fin1 (EC 2.7.11.1)| Length = 722 Score = 68.2 bits (165), Expect = 2e-11 Identities = 38/116 (32%), Positives = 68/116 (58%), Gaps = 4/116 (3%) Frame = +2 Query: 218 ESFEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRFMAREIHILRRLDNP 397 E ++ L+ IG G++ +YK + L++G ++A K++ F N+ + +++A E++ILR L +P Sbjct: 2 EKYKILECIGHGSFGRIYKVQRLKDGALLAQKEIHFGNITRQEKQYIADEVNILRNLKHP 61 Query: 398 NVIKLEGLVTSRMSSSLYLVFEYMEH-DLAGLA---ATPGIKFTEAQVKCYMQQLL 553 N+++ G +R + + L EY H DLA L +FTE +V + QLL Sbjct: 62 NIVQYCGEELNRSAQVINLYMEYCGHGDLANLIQRYKEEKKRFTEQEVLKFFTQLL 117
>PCTK2_MOUSE (Q8K0D0) Serine/threonine-protein kinase PCTAIRE-2 (EC 2.7.11.22)| (PCTAIRE-motif protein kinase 2) Length = 523 Score = 68.2 bits (165), Expect = 2e-11 Identities = 40/116 (34%), Positives = 66/116 (56%) Frame = +2 Query: 212 KAESFEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRFMAREIHILRRLD 391 K E++ KL+K+G+GTY++VYK R +VALK++R + + + RE+ +L+ L Sbjct: 188 KMETYIKLEKLGEGTYATVYKGRSKLTENLVALKEIRLEHEEGAPCTAI-REVSLLKDLK 246 Query: 392 NPNVIKLEGLVTSRMSSSLYLVFEYMEHDLAGLAATPGIKFTEAQVKCYMQQLLSG 559 + N++ L +V SL LVFEY++ DL G + VK ++ Q+L G Sbjct: 247 HANIVTLHDIV--HTDKSLTLVFEYLDKDLKQYMDDCGNIMSMHNVKLFLYQILRG 300
>PCTK2_HUMAN (Q00537) Serine/threonine-protein kinase PCTAIRE-2 (EC 2.7.11.22)| (PCTAIRE-motif protein kinase 2) Length = 523 Score = 68.2 bits (165), Expect = 2e-11 Identities = 40/116 (34%), Positives = 66/116 (56%) Frame = +2 Query: 212 KAESFEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRFMAREIHILRRLD 391 K E++ KL+K+G+GTY++VYK R +VALK++R + + + RE+ +L+ L Sbjct: 188 KMETYIKLEKLGEGTYATVYKGRSKLTENLVALKEIRLEHEEGAPCTAI-REVSLLKDLK 246 Query: 392 NPNVIKLEGLVTSRMSSSLYLVFEYMEHDLAGLAATPGIKFTEAQVKCYMQQLLSG 559 + N++ L +V SL LVFEY++ DL G + VK ++ Q+L G Sbjct: 247 HANIVTLHDIV--HTDKSLTLVFEYLDKDLKQYMDDCGNIMSMHNVKLFLYQILRG 300
>CC2H1_TRYBB (P38973) Cell division control protein 2 homolog 1 (EC 2.7.11.22)| Length = 301 Score = 67.8 bits (164), Expect = 2e-11 Identities = 41/112 (36%), Positives = 61/112 (54%) Frame = +2 Query: 224 FEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRFMAREIHILRRLDNPNV 403 +E+L KIG+G+Y V++ARD+ G IVA+K++R + REI IL+ L + N+ Sbjct: 5 YERLQKIGEGSYGVVFRARDVTTGTIVAVKRIRLEKEEEGVPCTAIREISILKELRHENI 64 Query: 404 IKLEGLVTSRMSSSLYLVFEYMEHDLAGLAATPGIKFTEAQVKCYMQQLLSG 559 ++L L L LVFE ME DL G ++ +M+ LLSG Sbjct: 65 VRL--LDVCHSEKRLTLVFECMEMDLKKYMDHVGGDLDAGTIQEFMRSLLSG 114
>CDKL4_HUMAN (Q5MAI5) Cyclin-dependent kinase-like 4 (EC 2.7.11.22)| Length = 315 Score = 67.8 bits (164), Expect = 2e-11 Identities = 34/88 (38%), Positives = 55/88 (62%) Frame = +2 Query: 218 ESFEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRFMAREIHILRRLDNP 397 E +EKL K G+G+Y V+K R+ +G++VA+KK + DP + REI +L++L +P Sbjct: 2 EKYEKLAKTGEGSYGVVFKCRNKTSGQVVAVKKFVESEDDPVVKKIALREIRMLKQLKHP 61 Query: 398 NVIKLEGLVTSRMSSSLYLVFEYMEHDL 481 N++ L + R ++LVFEY +H L Sbjct: 62 NLVNL--IEVFRRKRKMHLVFEYCDHTL 87
>CDC2H_PLAVI (Q9XZD6) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (Pvcrk2) Length = 288 Score = 67.8 bits (164), Expect = 2e-11 Identities = 42/114 (36%), Positives = 62/114 (54%) Frame = +2 Query: 218 ESFEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRFMAREIHILRRLDNP 397 E + L+KIG+GTY VYKA++ G+ ALKK+R D REI IL+ L + Sbjct: 2 EKYHGLEKIGEGTYGVVYKAQN-NYGETFALKKIRLEKEDEGIPSTAIREISILKELKHS 60 Query: 398 NVIKLEGLVTSRMSSSLYLVFEYMEHDLAGLAATPGIKFTEAQVKCYMQQLLSG 559 N++KL ++ ++ L LVFE+++ DL L K ++ QLLSG Sbjct: 61 NIVKLYDVIHTK--KRLILVFEHLDQDLKKLLDVCDGGLESVTAKSFLLQLLSG 112
>CDC2H_PLAKH (O96821) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) Length = 288 Score = 67.8 bits (164), Expect = 2e-11 Identities = 42/114 (36%), Positives = 62/114 (54%) Frame = +2 Query: 218 ESFEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRFMAREIHILRRLDNP 397 E + L+KIG+GTY VYKA++ G+ ALKK+R D REI IL+ L + Sbjct: 2 EKYHGLEKIGEGTYGVVYKAQN-NYGETFALKKIRLEKEDEGIPSTAIREISILKELKHS 60 Query: 398 NVIKLEGLVTSRMSSSLYLVFEYMEHDLAGLAATPGIKFTEAQVKCYMQQLLSG 559 N++KL ++ ++ L LVFE+++ DL L K ++ QLLSG Sbjct: 61 NIVKLYDVIHTK--KRLILVFEHLDQDLKKLLDVCDGGLESVTAKSFLLQLLSG 112
>CDK7_DICDI (P54685) Cell division protein kinase 7 (EC 2.7.11.22) (EC| 2.7.11.23) (CDK-activating kinase) (CAK) (MO15 homolog) Length = 362 Score = 67.4 bits (163), Expect = 3e-11 Identities = 43/110 (39%), Positives = 61/110 (55%), Gaps = 4/110 (3%) Frame = +2 Query: 242 IGQGTYSSVYKARDLENGKIVALKKVR---FANMDPESVRFMA-REIHILRRLDNPNVIK 409 IG+GTY V +A G+IVA+KK+R N + + F A REI IL+ L + NV+ Sbjct: 10 IGEGTYGVVSRATVKATGQIVAIKKIRKILIQNQTDDGINFSAIREIKILQELKHDNVVN 69 Query: 410 LEGLVTSRMSSSLYLVFEYMEHDLAGLAATPGIKFTEAQVKCYMQQLLSG 559 L + + S++YLVFE M+ DL + I A +K YM+ LL G Sbjct: 70 LLDIFAHK--SNVYLVFELMQWDLQEVIEDKSIILKPADIKSYMKMLLQG 117
>CDC2H_PLACH (Q4Y4B1) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) Length = 288 Score = 67.0 bits (162), Expect = 3e-11 Identities = 41/114 (35%), Positives = 63/114 (55%) Frame = +2 Query: 218 ESFEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRFMAREIHILRRLDNP 397 E + L+KIG+GTY VYKA++ +G+ ALKK+R D REI IL+ L + Sbjct: 2 EKYHGLEKIGEGTYGVVYKAQN-SDGESFALKKIRLEKEDEGIPSTAIREISILKELRHS 60 Query: 398 NVIKLEGLVTSRMSSSLYLVFEYMEHDLAGLAATPGIKFTEAQVKCYMQQLLSG 559 N++KL ++ ++ L LVFE+++ DL L K ++ QLL+G Sbjct: 61 NIVKLYDVIHAK--KRLILVFEHLDQDLKKLIDVCDGGLESVTAKSFLLQLLNG 112
>CDC2H_PLABA (Q4Z6R1) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) Length = 288 Score = 67.0 bits (162), Expect = 3e-11 Identities = 41/114 (35%), Positives = 63/114 (55%) Frame = +2 Query: 218 ESFEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRFMAREIHILRRLDNP 397 E + L+KIG+GTY VYKA++ +G+ ALKK+R D REI IL+ L + Sbjct: 2 EKYHGLEKIGEGTYGVVYKAQN-SDGESFALKKIRLEKEDEGIPSTAIREISILKELRHS 60 Query: 398 NVIKLEGLVTSRMSSSLYLVFEYMEHDLAGLAATPGIKFTEAQVKCYMQQLLSG 559 N++KL ++ ++ L LVFE+++ DL L K ++ QLL+G Sbjct: 61 NIVKLYDVIHAK--KRLILVFEHLDQDLKKLIDVCDGGLESVTAKSFLLQLLNG 112
>PHO85_CANAL (Q9HGY5) Negative regulator of the PHO system (EC 2.7.11.22)| (Serine/threonine-protein kinase PHO85) (CaPHO85) Length = 326 Score = 67.0 bits (162), Expect = 3e-11 Identities = 40/117 (34%), Positives = 67/117 (57%), Gaps = 2/117 (1%) Frame = +2 Query: 215 AESFEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRFMAREIHILRRLDN 394 + F++L+K+G+GTY++VYK R+ G +VALK++ + + + REI +++ LD+ Sbjct: 5 SSQFQQLEKLGEGTYATVYKGRNRATGALVALKEISL-DSEEGTPSTAIREISLMKELDH 63 Query: 395 PNVIKLEGLVTSRMSSSLYLVFEYMEHDLAGLAATPGIK--FTEAQVKCYMQQLLSG 559 N++ L ++ + L LVFEYM+ DL G + VK +M QLL G Sbjct: 64 ENIVTLYDVI--HTENKLTLVFEYMDKDLKKYMEVHGQQSALDLKVVKSFMFQLLKG 118
>CDKL4_MOUSE (Q3TZA2) Cyclin-dependent kinase-like 4 (EC 2.7.11.22)| Length = 342 Score = 66.6 bits (161), Expect = 4e-11 Identities = 34/88 (38%), Positives = 55/88 (62%) Frame = +2 Query: 218 ESFEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRFMAREIHILRRLDNP 397 E +EKL KIG+G+Y V+K R+ +G++VA+KK + D + REI +L++L +P Sbjct: 2 EKYEKLAKIGEGSYGVVFKCRNKSSGQVVAIKKFVESEDDRVVRKIALREIRMLKQLKHP 61 Query: 398 NVIKLEGLVTSRMSSSLYLVFEYMEHDL 481 N++ L + R ++LVFEY +H L Sbjct: 62 NLVNL--IEVFRRKRKMHLVFEYCDHTL 87
>BUR1_YEAST (P23293) Serine/threonine-protein kinase BUR1 (EC 2.7.11.22) (EC| 2.7.11.23) (Suppressor of GPA1-Vall50 mutation protein 1) (Bypass UAS requirement protein 1) Length = 657 Score = 66.6 bits (161), Expect = 4e-11 Identities = 42/120 (35%), Positives = 65/120 (54%), Gaps = 12/120 (10%) Frame = +2 Query: 236 DKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRFMA-REIHILRRLDNPNVIKL 412 +K+GQGT+ VYK LE + VA+KK+ +++ + A REI IL+RL++ N+IKL Sbjct: 64 EKLGQGTFGEVYKGIHLETQRQVAMKKI-IVSVEKDLFPITAQREITILKRLNHKNIIKL 122 Query: 413 EGLV-----------TSRMSSSLYLVFEYMEHDLAGLAATPGIKFTEAQVKCYMQQLLSG 559 +V +S + S Y++ YM DL+G+ P I +K M Q+L G Sbjct: 123 IEMVYDHSPDITNAASSNLHKSFYMILPYMVADLSGVLHNPRINLEMCDIKNMMLQILEG 182
>CDC2H_PLAFK (Q07785) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (PfPK5) Length = 288 Score = 66.2 bits (160), Expect = 6e-11 Identities = 41/114 (35%), Positives = 62/114 (54%) Frame = +2 Query: 218 ESFEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRFMAREIHILRRLDNP 397 E + L+KIG+GTY VYKA++ G+ ALKK+R D REI IL+ L + Sbjct: 2 EKYHGLEKIGEGTYGVVYKAQN-NYGETFALKKIRLEKEDEGIPSTTIREISILKELKHS 60 Query: 398 NVIKLEGLVTSRMSSSLYLVFEYMEHDLAGLAATPGIKFTEAQVKCYMQQLLSG 559 N++KL ++ ++ L LVFE+++ DL L K ++ QLL+G Sbjct: 61 NIVKLYDVIHTK--KRLVLVFEHLDQDLKKLLDVCEGGLESVTAKSFLLQLLNG 112
>CDC2H_PLAF7 (P61075) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) Length = 288 Score = 66.2 bits (160), Expect = 6e-11 Identities = 41/114 (35%), Positives = 62/114 (54%) Frame = +2 Query: 218 ESFEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRFMAREIHILRRLDNP 397 E + L+KIG+GTY VYKA++ G+ ALKK+R D REI IL+ L + Sbjct: 2 EKYHGLEKIGEGTYGVVYKAQN-NYGETFALKKIRLEKEDEGIPSTTIREISILKELKHS 60 Query: 398 NVIKLEGLVTSRMSSSLYLVFEYMEHDLAGLAATPGIKFTEAQVKCYMQQLLSG 559 N++KL ++ ++ L LVFE+++ DL L K ++ QLL+G Sbjct: 61 NIVKLYDVIHTK--KRLVLVFEHLDQDLKKLLDVCEGGLESVTAKSFLLQLLNG 112
>CCRK_PONPY (Q5R7I7) Cell cycle-related kinase (EC 2.7.11.22)| Length = 346 Score = 66.2 bits (160), Expect = 6e-11 Identities = 41/110 (37%), Positives = 61/110 (55%), Gaps = 1/110 (0%) Frame = +2 Query: 233 LDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRFMAREIHILRRL-DNPNVIK 409 L +IG+G + V+KA+ +E G+IVALKKV ++ REI L+ + DN V++ Sbjct: 7 LGRIGEGAHGIVFKAKHVETGEIVALKKVALRRLEDGIPNQALREIKALQEMEDNQYVVQ 66 Query: 410 LEGLVTSRMSSSLYLVFEYMEHDLAGLAATPGIKFTEAQVKCYMQQLLSG 559 L+ + S+ L FE+M DLA + +AQVK Y+Q LL G Sbjct: 67 LKAVFPH--SAGFVLAFEFMLSDLAEVVRHAQRPLAQAQVKSYLQMLLKG 114
>CDK5_DROME (P48609) Cell division protein kinase 5 homolog (EC 2.7.11.22)| Length = 294 Score = 66.2 bits (160), Expect = 6e-11 Identities = 39/114 (34%), Positives = 65/114 (57%) Frame = +2 Query: 218 ESFEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRFMAREIHILRRLDNP 397 + ++K++KIG+GTY +V+K R+ + +IVALK+VR D REI +L+ L + Sbjct: 2 QKYDKMEKIGEGTYGTVFKGRNRDTMEIVALKRVRLDEDDEGVPSSALREICLLKELKHK 61 Query: 398 NVIKLEGLVTSRMSSSLYLVFEYMEHDLAGLAATPGIKFTEAQVKCYMQQLLSG 559 N+++L ++ S L LVFE+ + DL + + A + +M QLL G Sbjct: 62 NIVRLIDVLHS--DKKLTLVFEHCDQDLKKYFDSLNGEIDMAVCRSFMLQLLRG 113
>CRK1_LEIME (Q06309) Cell division protein kinase 2 homolog CRK1 (EC 2.7.11.23)| Length = 301 Score = 65.9 bits (159), Expect = 8e-11 Identities = 39/112 (34%), Positives = 59/112 (52%) Frame = +2 Query: 224 FEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRFMAREIHILRRLDNPNV 403 +E+ +KIG+GTY VYKARD VALK++R + + REI +L+ L + N+ Sbjct: 5 YERQEKIGEGTYGVVYKARDTSTAATVALKRIRLDSEEEGVPCTAIREISLLKELRHENI 64 Query: 404 IKLEGLVTSRMSSSLYLVFEYMEHDLAGLAATPGIKFTEAQVKCYMQQLLSG 559 +KL L L +VFEY++ DL A ++ +M+ LL G Sbjct: 65 VKL--LDVCHSEHRLTIVFEYLDLDLKKYLDRENGNLDAATIQHFMRDLLRG 114
>ICK_RAT (Q62726) Serine/threonine-protein kinase ICK (EC 2.7.11.22)| (Intestinal cell kinase) (MAK-related kinase) (MRK) Length = 629 Score = 65.5 bits (158), Expect = 1e-10 Identities = 35/112 (31%), Positives = 66/112 (58%) Frame = +2 Query: 224 FEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRFMAREIHILRRLDNPNV 403 + + ++G GTY SV R +E+G+++A+KK++ E + RE+ L++L++ N+ Sbjct: 4 YTTIKQLGDGTYGSVLLGRSIESGELIAIKKMKRKFYSWEECMNL-REVKSLKKLNHANI 62 Query: 404 IKLEGLVTSRMSSSLYLVFEYMEHDLAGLAATPGIKFTEAQVKCYMQQLLSG 559 +KL+ ++ R + LY +FEYM+ +L L F E+ ++ M Q+L G Sbjct: 63 VKLKEVI--RENDHLYFIFEYMKENLYQLIKERNKLFPESAIRNIMYQILQG 112
>ICK_MOUSE (Q9JKV2) Serine/threonine-protein kinase ICK (EC 2.7.11.22)| (Intestinal cell kinase) (mICK) (MAK-related kinase) (MRK) Length = 629 Score = 65.5 bits (158), Expect = 1e-10 Identities = 35/112 (31%), Positives = 66/112 (58%) Frame = +2 Query: 224 FEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRFMAREIHILRRLDNPNV 403 + + ++G GTY SV R +E+G+++A+KK++ E + RE+ L++L++ N+ Sbjct: 4 YTTIKQLGDGTYGSVLLGRSIESGELIAIKKMKRKFYSWEECMNL-REVKSLKKLNHANI 62 Query: 404 IKLEGLVTSRMSSSLYLVFEYMEHDLAGLAATPGIKFTEAQVKCYMQQLLSG 559 +KL+ ++ R + LY +FEYM+ +L L F E+ ++ M Q+L G Sbjct: 63 VKLKEVI--RENDHLYFIFEYMKENLYQLIKERNKLFPESAIRNIMYQILQG 112
>CDC2H_PLAYO (Q7RM49) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) Length = 289 Score = 65.5 bits (158), Expect = 1e-10 Identities = 43/117 (36%), Positives = 66/117 (56%), Gaps = 3/117 (2%) Frame = +2 Query: 218 ESFEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMD---PESVRFMAREIHILRRL 388 E + L+KIG+GTY VYKA++ +G+ ALKK+R D P +V REI IL+ L Sbjct: 2 EKYHGLEKIGEGTYGVVYKAQN-SDGESFALKKIRLEKEDEGIPSTVSI--REISILKEL 58 Query: 389 DNPNVIKLEGLVTSRMSSSLYLVFEYMEHDLAGLAATPGIKFTEAQVKCYMQQLLSG 559 + N++KL ++ ++ L LVFE+++ DL L K ++ QLL+G Sbjct: 59 RHSNIVKLYDVIHAK--KRLILVFEHLDQDLKKLIDVCDGGLESVTAKSFLLQLLNG 113
>ICK_HUMAN (Q9UPZ9) Serine/threonine-protein kinase ICK (EC 2.7.11.22)| (Intestinal cell kinase) (hICK) (MAK-related kinase) (MRK) (Laryngeal cancer kinase 2) (LCK2) Length = 632 Score = 65.5 bits (158), Expect = 1e-10 Identities = 36/112 (32%), Positives = 66/112 (58%) Frame = +2 Query: 224 FEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRFMAREIHILRRLDNPNV 403 + + ++G GTY SV R +E+G+++A+KK++ E + RE+ L++L++ NV Sbjct: 4 YTTIRQLGDGTYGSVLLGRSIESGELIAIKKMKRKFYSWEECMNL-REVKSLKKLNHANV 62 Query: 404 IKLEGLVTSRMSSSLYLVFEYMEHDLAGLAATPGIKFTEAQVKCYMQQLLSG 559 +KL+ ++ R + LY +FEYM+ +L L F E+ ++ M Q+L G Sbjct: 63 VKLKEVI--RENDHLYFIFEYMKENLYQLIKERNKLFPESAIRNIMYQILQG 112
>NEK2_HUMAN (P51955) Serine/threonine-protein kinase Nek2 (EC 2.7.11.1)| (NimA-related protein kinase 2) (NimA-like protein kinase 1) (HSPK 21) Length = 445 Score = 65.5 bits (158), Expect = 1e-10 Identities = 32/102 (31%), Positives = 55/102 (53%) Frame = +2 Query: 206 PRKAESFEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRFMAREIHILRR 385 P +AE +E L IG G+Y K R +GKI+ K++ + +M + + E+++LR Sbjct: 2 PSRAEDYEVLYTIGTGSYGRCQKIRRKSDGKILVWKELDYGSMTEAEKQMLVSEVNLLRE 61 Query: 386 LDNPNVIKLEGLVTSRMSSSLYLVFEYMEHDLAGLAATPGIK 511 L +PN+++ + R +++LY+V EY E T G K Sbjct: 62 LKHPNIVRYYDRIIDRTNTTLYIVMEYCEGGDLASVITKGTK 103
>MK15_HUMAN (Q8TD08) Mitogen-activated protein kinase 15 (EC 2.7.11.24)| (Extracellular signal-regulated kinase 8) Length = 544 Score = 65.1 bits (157), Expect = 1e-10 Identities = 39/117 (33%), Positives = 62/117 (52%), Gaps = 1/117 (0%) Frame = +2 Query: 206 PRKAESFEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRFMAREIHILRR 385 PR + ++GQG Y V+KA D G++VA+KK+ A D + REI +L+ Sbjct: 7 PRIVRRYLLRRQLGQGAYGIVWKAVDRRTGEVVAIKKIFDAFRDKTDAQRTFREITLLQE 66 Query: 386 L-DNPNVIKLEGLVTSRMSSSLYLVFEYMEHDLAGLAATPGIKFTEAQVKCYMQQLL 553 D+PN+I L ++ + +YLVFE+M+ DL + G+ + V+ QLL Sbjct: 67 FGDHPNIISLLDVIRAENDRDIYLVFEFMDTDLNAVIRKGGL-LQDVHVRSIFYQLL 122
>CDC2B_ARATH (P25859) Cell division control protein 2 homolog B (EC 2.7.11.22)| (EC 2.7.11.23) Length = 309 Score = 65.1 bits (157), Expect = 1e-10 Identities = 42/98 (42%), Positives = 57/98 (58%), Gaps = 10/98 (10%) Frame = +2 Query: 218 ESFEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRFMA-REIHILRRLDN 394 E +EKL+K+G+GTY VYKA + GK+VALKK R MD E + A REI +L+ L Sbjct: 2 EKYEKLEKVGEGTYGKVYKAMEKGTGKLVALKKTRL-EMDEEGIPPTALREISLLQMLST 60 Query: 395 P-NVIKL--------EGLVTSRMSSSLYLVFEYMEHDL 481 V++L + S+LYLVFEY++ DL Sbjct: 61 SIYVVRLLCVEHVHQPSTKSQSTKSNLYLVFEYLDTDL 98
>CDK7_CARAU (P51953) Cell division protein kinase 7 (EC 2.7.11.22) (EC| 2.7.11.23) (40 kDa protein kinase) (P40 MO15) (CDC2/CDK2,4-activating kinase) Length = 344 Score = 64.7 bits (156), Expect = 2e-10 Identities = 40/119 (33%), Positives = 64/119 (53%), Gaps = 3/119 (2%) Frame = +2 Query: 212 KAESFEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPES---VRFMAREIHILR 382 +A+ +EKLD +G+G +++VYKARD IVA+KK++ + R REI +L+ Sbjct: 8 RAKLYEKLDFLGEGQFATVYKARDKTTNTIVAIKKIKVGHRTEAKDGINRTALREIKLLQ 67 Query: 383 RLDNPNVIKLEGLVTSRMSSSLYLVFEYMEHDLAGLAATPGIKFTEAQVKCYMQQLLSG 559 L +PN+I GL+ + S + +ME DL + + T A +K Y+ L G Sbjct: 68 ELSHPNII---GLLDAFGHKSNISLLCFMETDLEVIIKDTSLVLTPANIKAYILMSLQG 123
>CDC2_SCHPO (P04551) Cell division control protein 2 (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinse) Length = 297 Score = 64.3 bits (155), Expect = 2e-10 Identities = 40/122 (32%), Positives = 69/122 (56%), Gaps = 8/122 (6%) Frame = +2 Query: 218 ESFEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRFMAREIHILRRLDN- 394 E+++K++KIG+GTY VYKAR +G+IVA+KK+R + REI +L+ +++ Sbjct: 2 ENYQKVEKIGEGTYGVVYKARHKLSGRIVAMKKIRLEDESEGVPSTAIREISLLKEVNDE 61 Query: 395 ---PNVIKLEGLVTSRMSSSLYLVFEYMEHDLA----GLAATPGIKFTEAQVKCYMQQLL 553 N ++L ++ S LYLVFE+++ DL ++ T V+ + QL+ Sbjct: 62 NNRSNCVRLLDIL--HAESKLYLVFEFLDMDLKKYMDRISETGATSLDPRLVQKFTYQLV 119 Query: 554 SG 559 +G Sbjct: 120 NG 121
>CCRK_HUMAN (Q8IZL9) Cell cycle-related kinase (EC 2.7.11.22)| (Cyclin-kinase-activating kinase p42) (CDK-activating kinase p42) (CAK-kinase p42) Length = 346 Score = 64.3 bits (155), Expect = 2e-10 Identities = 40/110 (36%), Positives = 59/110 (53%), Gaps = 1/110 (0%) Frame = +2 Query: 233 LDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRFMAREIHILRRL-DNPNVIK 409 L +IG+G + V+KA+ +E G+IVALKKV ++ REI L+ + DN V++ Sbjct: 7 LGRIGEGAHGIVFKAKHVETGEIVALKKVALRRLEDGFPNQALREIKALQEMEDNQYVVQ 66 Query: 410 LEGLVTSRMSSSLYLVFEYMEHDLAGLAATPGIKFTEAQVKCYMQQLLSG 559 L+ + L FE+M DLA + +AQVK Y+Q LL G Sbjct: 67 LKAVFPH--GGGFVLAFEFMLSDLAEVVRHAQRPLAQAQVKSYLQMLLKG 114
>CCRK_MACMU (Q5EDC3) Cell cycle-related kinase (EC 2.7.11.22)| (Cyclin-kinase-activating kinase p42) (CDK-activating kinase p42) (CAK-kinase p42) Length = 243 Score = 64.3 bits (155), Expect = 2e-10 Identities = 40/110 (36%), Positives = 59/110 (53%), Gaps = 1/110 (0%) Frame = +2 Query: 233 LDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRFMAREIHILRRL-DNPNVIK 409 L +IG+G + V+KA+ +E G+IVALKKV ++ REI L+ + DN V++ Sbjct: 7 LGRIGEGAHGIVFKAKHVETGEIVALKKVALRRLEDGFPNQALREIKALQEMGDNQYVVQ 66 Query: 410 LEGLVTSRMSSSLYLVFEYMEHDLAGLAATPGIKFTEAQVKCYMQQLLSG 559 L+ + L FE+M DLA + +AQVK Y+Q LL G Sbjct: 67 LKAVFPH--GGGFVLAFEFMLSDLAEVVRHAQRPLAQAQVKSYLQMLLKG 114
>YP62_CAEEL (Q09437) Putative serine/threonine-protein kinase B0495.2 (EC| 2.7.11.1) Length = 719 Score = 63.9 bits (154), Expect = 3e-10 Identities = 37/124 (29%), Positives = 70/124 (56%), Gaps = 7/124 (5%) Frame = +2 Query: 209 RKAESFEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRF---MAREIHIL 379 R + +E ++++ +GT+ VY+ +D +IVALK+++ M+ E F REI++L Sbjct: 351 RNIDEYECVNRVDEGTFGVVYRGKDKRTDEIVALKRLK---MEKEKEGFPITALREINML 407 Query: 380 RRLDN-PNVIKLEGLVTSRMSSSLYLVFEYMEHDLAGLAAT---PGIKFTEAQVKCYMQQ 547 + N PN++ ++ ++ +Y+ E++EHD+ L T +F+ + K +QQ Sbjct: 408 LKAGNHPNIVNVKEILLGSNMDKIYMAMEFVEHDMKSLLDTMSRRNKRFSIGEQKTLLQQ 467 Query: 548 LLSG 559 LLSG Sbjct: 468 LLSG 471
>NEK2_MOUSE (O35942) Serine/threonine-protein kinase Nek2 (EC 2.7.11.1)| (NimA-related protein kinase 2) Length = 443 Score = 63.9 bits (154), Expect = 3e-10 Identities = 31/96 (32%), Positives = 55/96 (57%), Gaps = 1/96 (1%) Frame = +2 Query: 206 PRKAESFEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRFMAREIHILRR 385 P + E +E L IG G+Y K R +GKI+ K++ + +M + + E+++LR Sbjct: 2 PSRVEDYEVLHSIGTGSYGRCQKIRRKSDGKILVWKELDYGSMTEVEKQMLVSEVNLLRE 61 Query: 386 LDNPNVIKLEGLVTSRMSSSLYLVFEYME-HDLAGL 490 L +PN+++ + R +++LY+V EY E DLA + Sbjct: 62 LKHPNIVRYYDRIIDRTNTTLYIVMEYCEGGDLASV 97
>CDC7_SCHPO (P41892) Cell division control protein 7 (EC 2.7.11.1)| Length = 1062 Score = 63.9 bits (154), Expect = 3e-10 Identities = 38/117 (32%), Positives = 66/117 (56%), Gaps = 1/117 (0%) Frame = +2 Query: 212 KAESFEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRFMAREIHILRRLD 391 +A S D +G+G + +VY+ +++NG+ VA+KKV+ + M + + EI +L+ LD Sbjct: 5 QASSITLGDCLGKGAFGAVYRGLNIKNGETVAVKKVKLSKMLKSDLSVIKMEIDLLKNLD 64 Query: 392 NPNVIKLEGLVTSRMSSSLYLVFEYMEH-DLAGLAATPGIKFTEAQVKCYMQQLLSG 559 +PN++K G + + + SL ++ EY E+ L + G K E V Y Q+L G Sbjct: 65 HPNIVKYRG--SYQTNDSLCIILEYCENGSLRSICKNFG-KIPENLVALYTFQVLQG 118
>CDK6_MOUSE (Q64261) Cell division protein kinase 6 (EC 2.7.11.22)| (Serine/threonine-protein kinase PLSTIRE) (CRK2) Length = 326 Score = 63.5 bits (153), Expect = 4e-10 Identities = 45/125 (36%), Positives = 68/125 (54%), Gaps = 8/125 (6%) Frame = +2 Query: 209 RKAESFEKLDKIGQGTYSSVYKARDLEN-GKIVALKKVRFANMDPESVRFMAREIHILRR 385 R + +E + +IG+G Y V+KARDL+N G+ VALK+VR + RE+ +LR Sbjct: 8 RADQQYECVAEIGEGAYGKVFKARDLKNGGRFVALKRVRVQTSEEGMPLSTIREVAVLRH 67 Query: 386 L---DNPNVIKLEGLVT---SRMSSSLYLVFEYMEHDLAG-LAATPGIKFTEAQVKCYMQ 544 L ++PNV++L + T + + L LVFE+++ DL L P +K M Sbjct: 68 LETFEHPNVVRLFDVCTVSRTDRETKLTLVFEHVDQDLTTYLDKVPEPGVPTETIKDMMF 127 Query: 545 QLLSG 559 QLL G Sbjct: 128 QLLRG 132
>CDC2C_ANTMA (Q38774) Cell division control protein 2 homolog C (EC 2.7.11.22)| (EC 2.7.11.23) Length = 305 Score = 63.2 bits (152), Expect = 5e-10 Identities = 39/94 (41%), Positives = 57/94 (60%), Gaps = 6/94 (6%) Frame = +2 Query: 218 ESFEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRFMA-REIHILRRLDN 394 E +EKL+K+G+GTY VYKA + G++VALKK R MD E V A RE+ +L+ L Sbjct: 2 EKYEKLEKVGEGTYGKVYKALEKSTGQVVALKKTRL-EMDEEGVPPTALREVSLLQMLSQ 60 Query: 395 P----NVIKLEGLVTSRMSSS-LYLVFEYMEHDL 481 ++ +E + ++ LYLVFEY++ DL Sbjct: 61 SLYVVRLLSVEHVDCAKNGKPLLYLVFEYLDTDL 94
>CD2L6_MOUSE (Q8BWD8) Cell division cycle 2-like protein kinase 6 (EC 2.7.11.22)| (CDC2-related protein kinase 6) Length = 501 Score = 62.8 bits (151), Expect = 6e-10 Identities = 41/117 (35%), Positives = 62/117 (52%), Gaps = 10/117 (8%) Frame = +2 Query: 239 KIGQGTYSSVYKAR--DLENGKIVALKKVRFANMDPESVRFMAREIHILRRLDNPNVIKL 412 K+G+GTY VYKAR D ++ K ALK++ + + REI +LR L +PNVI L Sbjct: 26 KVGRGTYGHVYKARRKDGKDEKEYALKQIEGTGISMSA----CREIALLRELKHPNVIAL 81 Query: 413 EGLVTSRMSSSLYLVFEYMEHDL--------AGLAATPGIKFTEAQVKCYMQQLLSG 559 + + S ++L+F+Y EHDL A A ++ + VK + Q+L G Sbjct: 82 QKVFLSHSDRKVWLLFDYAEHDLWHIIKFHRASKANKKPMQLPRSMVKSLLYQILDG 138
>CD2L6_HUMAN (Q9BWU1) Cell division cycle 2-like protein kinase 6 (EC 2.7.11.22)| (CDC2-related protein kinase 6) (Death-preventing kinase) (Cyclin-dependent kinase 11) Length = 502 Score = 62.8 bits (151), Expect = 6e-10 Identities = 41/117 (35%), Positives = 62/117 (52%), Gaps = 10/117 (8%) Frame = +2 Query: 239 KIGQGTYSSVYKAR--DLENGKIVALKKVRFANMDPESVRFMAREIHILRRLDNPNVIKL 412 K+G+GTY VYKAR D ++ K ALK++ + + REI +LR L +PNVI L Sbjct: 26 KVGRGTYGHVYKARRKDGKDEKEYALKQIEGTGISMSA----CREIALLRELKHPNVIAL 81 Query: 413 EGLVTSRMSSSLYLVFEYMEHDL--------AGLAATPGIKFTEAQVKCYMQQLLSG 559 + + S ++L+F+Y EHDL A A ++ + VK + Q+L G Sbjct: 82 QKVFLSHSDRKVWLLFDYAEHDLWHIIKFHRASKANKKPMQLPRSMVKSLLYQILDG 138
>CDK6_HUMAN (Q00534) Cell division protein kinase 6 (EC 2.7.11.22)| (Serine/threonine-protein kinase PLSTIRE) Length = 326 Score = 62.8 bits (151), Expect = 6e-10 Identities = 45/125 (36%), Positives = 68/125 (54%), Gaps = 8/125 (6%) Frame = +2 Query: 209 RKAESFEKLDKIGQGTYSSVYKARDLEN-GKIVALKKVRFANMDPESVRFMAREIHILRR 385 R + +E + +IG+G Y V+KARDL+N G+ VALK+VR + RE+ +LR Sbjct: 8 RADQQYECVAEIGEGAYGKVFKARDLKNGGRFVALKRVRVQTGEEGMPLSTIREVAVLRH 67 Query: 386 L---DNPNVIKLEGLVT---SRMSSSLYLVFEYMEHDLAG-LAATPGIKFTEAQVKCYMQ 544 L ++PNV++L + T + + L LVFE+++ DL L P +K M Sbjct: 68 LETFEHPNVVRLFDVCTVSRTDRETKLTLVFEHVDQDLTTYLDKVPEPGVPTETIKDMMF 127 Query: 545 QLLSG 559 QLL G Sbjct: 128 QLLRG 132
>CDK8_HUMAN (P49336) Cell division protein kinase 8 (EC 2.7.11.22) (EC| 2.7.11.23) (Protein kinase K35) Length = 464 Score = 62.8 bits (151), Expect = 6e-10 Identities = 40/117 (34%), Positives = 61/117 (52%), Gaps = 10/117 (8%) Frame = +2 Query: 239 KIGQGTYSSVYKAR--DLENGKIVALKKVRFANMDPESVRFMAREIHILRRLDNPNVIKL 412 K+G+GTY VYKA+ D ++ K ALK++ + + REI +LR L +PNVI L Sbjct: 26 KVGRGTYGHVYKAKRKDGKDDKDYALKQIEGTGISMSA----CREIALLRELKHPNVISL 81 Query: 413 EGLVTSRMSSSLYLVFEYMEHDL--------AGLAATPGIKFTEAQVKCYMQQLLSG 559 + + S ++L+F+Y EHDL A A ++ VK + Q+L G Sbjct: 82 QKVFLSHADRKVWLLFDYAEHDLWHIIKFHRASKANKKPVQLPRGMVKSLLYQILDG 138
>MAK_MOUSE (Q04859) Serine/threonine-protein kinase MAK (EC 2.7.11.22) (Male| germ cell-associated kinase) (Protein kinase RCK) Length = 622 Score = 62.4 bits (150), Expect = 8e-10 Identities = 39/114 (34%), Positives = 68/114 (59%), Gaps = 2/114 (1%) Frame = +2 Query: 224 FEKLDKIGQGTYSSVYKARDLENGKIVALKKV--RFANMDPESVRFMAREIHILRRLDNP 397 + + ++G GTY SV + E+G++VA+K++ +F + D E + RE+ L++L++ Sbjct: 4 YTTMKQLGDGTYGSVLMGKSNESGELVAIKRMKRKFYSWD-ECMNL--REVKSLKKLNHA 60 Query: 398 NVIKLEGLVTSRMSSSLYLVFEYMEHDLAGLAATPGIKFTEAQVKCYMQQLLSG 559 NVIKL+ ++ R + LY VFEYM+ +L L F E+ ++ M Q+L G Sbjct: 61 NVIKLKEVI--RENDHLYFVFEYMKENLYQLMKDRNKLFPESVIRNIMYQILQG 112
>MK15_RAT (Q9Z2A6) Mitogen-activated protein kinase 15 (EC 2.7.11.24)| (Extracellular signal-regulated kinase 7) Length = 547 Score = 61.6 bits (148), Expect = 1e-09 Identities = 36/106 (33%), Positives = 57/106 (53%), Gaps = 1/106 (0%) Frame = +2 Query: 239 KIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRFMAREIHILRRL-DNPNVIKLE 415 ++G+G Y V+KA D G++VA+KK+ A D + REI +LR +PN+I+L Sbjct: 19 RLGKGAYGIVWKAMDRRTGEVVAIKKIFDAFRDQTDAQRTFREIMLLREFGGHPNIIRLL 78 Query: 416 GLVTSRMSSSLYLVFEYMEHDLAGLAATPGIKFTEAQVKCYMQQLL 553 ++ ++ +YLVFE M+ DL G + +C QLL Sbjct: 79 DVIPAKNDRDIYLVFESMDTDL-NAVIQKGRLLEDIHKRCIFYQLL 123
>MAK_HUMAN (P20794) Serine/threonine-protein kinase MAK (EC 2.7.11.22) (Male| germ cell-associated kinase) Length = 623 Score = 61.6 bits (148), Expect = 1e-09 Identities = 38/114 (33%), Positives = 68/114 (59%), Gaps = 2/114 (1%) Frame = +2 Query: 224 FEKLDKIGQGTYSSVYKARDLENGKIVALKKV--RFANMDPESVRFMAREIHILRRLDNP 397 + + ++G GTY SV + E+G++VA+K++ +F + D E + RE+ L++L++ Sbjct: 4 YTTMRQLGDGTYGSVLMGKSNESGELVAIKRMKRKFYSWD-ECMNL--REVKSLKKLNHA 60 Query: 398 NVIKLEGLVTSRMSSSLYLVFEYMEHDLAGLAATPGIKFTEAQVKCYMQQLLSG 559 NVIKL+ ++ R + LY +FEYM+ +L L F E+ ++ M Q+L G Sbjct: 61 NVIKLKEVI--RENDHLYFIFEYMKENLYQLMKDRNKLFPESVIRNIMYQILQG 112
>AL2S7_HUMAN (Q96Q40) Serine/threonine-protein kinase ALS2CR7 (EC 2.7.11.22)| (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 7 protein) Length = 384 Score = 61.6 bits (148), Expect = 1e-09 Identities = 46/129 (35%), Positives = 72/129 (55%), Gaps = 7/129 (5%) Frame = +2 Query: 194 RGWQPRK------AESFEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRF 355 +G+Q RK A S+ L+K+G+G+Y++VYK NG++VALK + N + E V F Sbjct: 36 QGFQWRKSLPFGAASSYLNLEKLGEGSYATVYKGISRINGQLVALKVISM-NAE-EGVPF 93 Query: 356 MA-REIHILRRLDNPNVIKLEGLVTSRMSSSLYLVFEYMEHDLAGLAATPGIKFTEAQVK 532 A RE +L+ L + N++ L ++ ++ +L VFEYM DLA + V+ Sbjct: 94 TAIREASLLKGLKHANIVLLHDIIHTK--ETLTFVFEYMHTDLAQYMSQHPGGLHPHNVR 151 Query: 533 CYMQQLLSG 559 +M QLL G Sbjct: 152 LFMFQLLRG 160
>CCRK_RAT (Q4KM34) Cell cycle-related kinase (EC 2.7.11.22)| Length = 346 Score = 61.6 bits (148), Expect = 1e-09 Identities = 39/110 (35%), Positives = 59/110 (53%), Gaps = 1/110 (0%) Frame = +2 Query: 233 LDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRFMAREIHILRRL-DNPNVIK 409 L +IG+G + V+KA+ +E G+IVALKKV ++ REI L+ + D+ V++ Sbjct: 7 LGRIGEGAHGIVFKAKHVETGEIVALKKVALRRLEDGIPNQALREIKALQEIEDSQYVVQ 66 Query: 410 LEGLVTSRMSSSLYLVFEYMEHDLAGLAATPGIKFTEAQVKCYMQQLLSG 559 L+ + + L FE+M DLA + AQVK Y+Q LL G Sbjct: 67 LKAVFPH--GAGFVLAFEFMLSDLAEVVRHAQRPLAPAQVKSYLQMLLKG 114
>CCRK_MOUSE (Q9JHU3) Cell cycle-related kinase (EC 2.7.11.22)| (Cyclin-kinase-activating kinase p42) (CDK-activating kinase p42) (CAK-kinase p42) (CDK-related protein kinase PNQLARE) Length = 346 Score = 61.6 bits (148), Expect = 1e-09 Identities = 39/110 (35%), Positives = 59/110 (53%), Gaps = 1/110 (0%) Frame = +2 Query: 233 LDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRFMAREIHILRRL-DNPNVIK 409 L +IG+G + V+KA+ +E G+IVALKKV ++ REI L+ + D+ V++ Sbjct: 7 LGRIGEGAHGIVFKAKHVETGEIVALKKVALRRLEDGIPNQALREIKALQEIEDSQYVVQ 66 Query: 410 LEGLVTSRMSSSLYLVFEYMEHDLAGLAATPGIKFTEAQVKCYMQQLLSG 559 L+ + + L FE+M DLA + AQVK Y+Q LL G Sbjct: 67 LKAVFPH--GAGFVLAFEFMLSDLAEVVRHAQRPLAPAQVKSYLQMLLKG 114
>MAK_RAT (P20793) Serine/threonine-protein kinase MAK (EC 2.7.11.22) (Male| germ cell-associated kinase) Length = 622 Score = 61.6 bits (148), Expect = 1e-09 Identities = 38/114 (33%), Positives = 68/114 (59%), Gaps = 2/114 (1%) Frame = +2 Query: 224 FEKLDKIGQGTYSSVYKARDLENGKIVALKKV--RFANMDPESVRFMAREIHILRRLDNP 397 + + ++G GTY SV + E+G++VA+K++ +F + D E + RE+ L++L++ Sbjct: 4 YTTMRQLGDGTYGSVLMGKSNESGELVAIKRMKRKFYSWD-ECMNL--REVKSLKKLNHA 60 Query: 398 NVIKLEGLVTSRMSSSLYLVFEYMEHDLAGLAATPGIKFTEAQVKCYMQQLLSG 559 NVIKL+ ++ R + LY +FEYM+ +L L F E+ ++ M Q+L G Sbjct: 61 NVIKLKEVI--RENDHLYFIFEYMKENLYQLMKDRNKLFPESVIRNIMYQILQG 112
>CDKL5_HUMAN (O76039) Cyclin-dependent kinase-like 5 (EC 2.7.11.22)| (Serine/threonine-protein kinase 9) Length = 1030 Score = 60.8 bits (146), Expect = 2e-09 Identities = 38/110 (34%), Positives = 57/110 (51%) Frame = +2 Query: 224 FEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRFMAREIHILRRLDNPNV 403 FE L +G+G Y V K R E +IVA+KK + + + E RE+ +LR L N+ Sbjct: 13 FEILGVVGEGAYGVVLKCRHKETHEIVAIKKFKDSEENEEVKETTLRELKMLRTLKQENI 72 Query: 404 IKLEGLVTSRMSSSLYLVFEYMEHDLAGLAATPGIKFTEAQVKCYMQQLL 553 ++L+ R LYLVFEY+E ++ L +VK Y+ QL+ Sbjct: 73 VELK--EAFRRRGKLYLVFEYVEKNMLELLEEMPNGVPPEKVKSYIYQLI 120
>CDC21_PEA (P19026) Cell division control protein 2 homolog 1 (EC 2.7.11.22)| (EC 2.7.11.23) (p34) (Fragment) Length = 148 Score = 60.8 bits (146), Expect = 2e-09 Identities = 36/99 (36%), Positives = 56/99 (56%), Gaps = 1/99 (1%) Frame = +2 Query: 266 VYKARDLENGKIVALKKVRFANMDPESVRFMAREIHILRRLDNPNVIKLEGLVTSRMSSS 445 VYKARD + +ALKK+R D REI +L+ + + N+++L+ +V S Sbjct: 2 VYKARDRVTNETIALKKIRLEQEDEGVPSTAIREISLLKEMQHRNIVRLQDVVHS--EKR 59 Query: 446 LYLVFEYMEHDL-AGLAATPGIKFTEAQVKCYMQQLLSG 559 LYLVFEY++ DL + ++P QVK ++ Q+L G Sbjct: 60 LYLVFEYLDLDLKKHMDSSPEFVKDPRQVKMFLYQMLCG 98
>CDK4_MOUSE (P30285) Cell division protein kinase 4 (EC 2.7.11.22)| (Cyclin-dependent kinase 4) (PSK-J3) (CRK3) Length = 303 Score = 60.5 bits (145), Expect = 3e-09 Identities = 48/127 (37%), Positives = 67/127 (52%), Gaps = 12/127 (9%) Frame = +2 Query: 215 AESFEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRF---MAREIHILRR 385 A +E + +IG G Y +VYKARD +G VALK VR N RE+ +LRR Sbjct: 3 ATRYEPVAEIGVGAYGTVYKARDPHSGHFVALKSVRVPNGGAAGGGLPVSTVREVALLRR 62 Query: 386 L---DNPNVIKL-EGLVTSRMSSSL--YLVFEYMEHDL---AGLAATPGIKFTEAQVKCY 538 L ++PNV++L + TSR + LVFE+++ DL A PG+ +K Sbjct: 63 LEAFEHPNVVRLMDVCATSRTDRDIKVTLVFEHIDQDLRTYLDKAPPPGLPV--ETIKDL 120 Query: 539 MQQLLSG 559 M+Q LSG Sbjct: 121 MRQFLSG 127
>BUR1_CANGA (Q6FQ83) Serine/threonine-protein kinase BUR1 (EC 2.7.11.22) (EC| 2.7.11.23) Length = 667 Score = 60.5 bits (145), Expect = 3e-09 Identities = 41/137 (29%), Positives = 68/137 (49%), Gaps = 24/137 (17%) Frame = +2 Query: 221 SFEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRFMA-REIHILRRLDNP 397 ++++ +K+GQGT+ VYK L+ + VA+K++ N + + A REI IL+RL++ Sbjct: 59 NYKEEEKLGQGTFGEVYKGLHLQTQRKVAMKRI-IVNQENDLFPITAQREITILKRLNHK 117 Query: 398 NVIKLEGLVTSRMSSS-----------------------LYLVFEYMEHDLAGLAATPGI 508 N+IKL +V S Y++ YM DL+G+ P I Sbjct: 118 NIIKLLEMVYDFPPESNNKDYAQFNQNNSANPPAVPKKFFYMILPYMVADLSGILHNPRI 177 Query: 509 KFTEAQVKCYMQQLLSG 559 + A +K M+Q+L G Sbjct: 178 ELKMADIKNMMKQILEG 194
>CDKL2_RABIT (Q9TTK0) Cyclin-dependent kinase-like 2 (EC 2.7.11.22)| (Serine/threonine-protein kinase KKIAMRE) Length = 566 Score = 60.1 bits (144), Expect = 4e-09 Identities = 34/114 (29%), Positives = 63/114 (55%) Frame = +2 Query: 218 ESFEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRFMAREIHILRRLDNP 397 E +E L +G+G+Y V K R+ ++G+IVA+KK ++ D + REI +L++L + Sbjct: 2 EKYENLGLVGEGSYGMVMKCRNKDSGRIVAIKKFLESDDDKMVKKIAMREIKLLKQLRHE 61 Query: 398 NVIKLEGLVTSRMSSSLYLVFEYMEHDLAGLAATPGIKFTEAQVKCYMQQLLSG 559 N++ L L + YLVFE+++H + + V+ Y+ Q+++G Sbjct: 62 NLVNL--LEVCKKKKRWYLVFEFVDHTILDDLELFPNGLDDQVVQKYLFQIING 113
>CDC2B_ANTMA (Q38773) Cell division control protein 2 homolog B (EC 2.7.11.22)| (EC 2.7.11.23) (Fragment) Length = 280 Score = 60.1 bits (144), Expect = 4e-09 Identities = 36/102 (35%), Positives = 55/102 (53%), Gaps = 1/102 (0%) Frame = +2 Query: 257 YSSVYKARDLENGKIVALKKVRFANMDPESVRFMAREIHILRRLDNPNVIKLEGLVTSRM 436 Y VYKARD+E + +ALKK+R D REI +L+ + + N++ L+ +V Sbjct: 2 YGVVYKARDIETNEDIALKKIRLEQEDEGVPSTAIREISLLKEMHHENIVNLKDVV--HR 59 Query: 437 SSSLYLVFEYMEHDL-AGLAATPGIKFTEAQVKCYMQQLLSG 559 LYLVFEY++ DL + + P VK ++ Q+L G Sbjct: 60 EKRLYLVFEYLDLDLKKHMDSCPEFSQDLHMVKMFLCQILRG 101
>MOK_MOUSE (Q9WVS4) MAPK/MAK/MRK overlapping kinase (EC 2.7.11.22) (MOK| protein kinase) Length = 420 Score = 59.7 bits (143), Expect = 5e-09 Identities = 38/112 (33%), Positives = 63/112 (56%), Gaps = 1/112 (0%) Frame = +2 Query: 218 ESFEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRFMAREIHILRRLD-N 394 ++++ + KIG+GT+S V K + L +G A K+++ E V + REI LRRL+ + Sbjct: 2 KNYKAIGKIGEGTFSEVMKMQSLRDGNYYACKQMKQHFESIEQVNSL-REIQALRRLNPH 60 Query: 395 PNVIKLEGLVTSRMSSSLYLVFEYMEHDLAGLAATPGIKFTEAQVKCYMQQL 550 PN++ L +V R S SL L+ E M+ ++ L +E ++ YM QL Sbjct: 61 PNILALHEVVFDRKSGSLALICELMDMNIYELIRGRRHPLSEKKIMLYMYQL 112
>CDK4_RAT (P35426) Cell division protein kinase 4 (EC 2.7.11.22)| (Cyclin-dependent kinase 4) (PSK-J3) Length = 303 Score = 59.7 bits (143), Expect = 5e-09 Identities = 47/124 (37%), Positives = 66/124 (53%), Gaps = 12/124 (9%) Frame = +2 Query: 224 FEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRF---MAREIHILRRL-- 388 +E + +IG G Y +VYKARD +G VALK VR N RE+ +LRRL Sbjct: 6 YEPVAEIGVGAYGTVYKARDPHSGHFVALKSVRVPNGGAAGGGLPVSTVREVALLRRLEA 65 Query: 389 -DNPNVIKL-EGLVTSRMSSSL--YLVFEYMEHDL---AGLAATPGIKFTEAQVKCYMQQ 547 ++PNV++L + TSR + LVFE+++ DL A PG+ +K M+Q Sbjct: 66 FEHPNVVRLMDVCATSRTDRDIKVTLVFEHIDQDLRTYLDKAPPPGLPV--ETIKDLMRQ 123 Query: 548 LLSG 559 LSG Sbjct: 124 FLSG 127
>CDKL2_MOUSE (Q9QUK0) Cyclin-dependent kinase-like 2 (EC 2.7.11.22)| (Serine/threonine-protein kinase KKIAMRE) Length = 568 Score = 59.7 bits (143), Expect = 5e-09 Identities = 38/116 (32%), Positives = 66/116 (56%), Gaps = 2/116 (1%) Frame = +2 Query: 218 ESFEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRFMAREIHILRRLDNP 397 E +E L +G+G+Y V K R+ ++G+IVA+KK ++ D + REI +L++L + Sbjct: 2 EKYENLGLVGEGSYGMVMKCRNKDSGRIVAIKKFLESDDDKMVKKIAMREIKLLKQLRHE 61 Query: 398 NVIKLEGLVTSRMSSSLYLVFEYMEHD-LAGLAATP-GIKFTEAQVKCYMQQLLSG 559 N++ L L + YLVFE+++H L L P G+ + Q Y+ Q+++G Sbjct: 62 NLVNL--LEVCKKKKRWYLVFEFVDHTILDDLKLFPNGLDYQVVQK--YLFQIING 113
>MK15_MOUSE (Q80Y86) Mitogen-activated protein kinase 15 (EC 2.7.11.24)| (Extracellular signal-regulated kinase 7) Length = 549 Score = 59.7 bits (143), Expect = 5e-09 Identities = 35/106 (33%), Positives = 57/106 (53%), Gaps = 1/106 (0%) Frame = +2 Query: 239 KIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRFMAREIHILRRL-DNPNVIKLE 415 ++G+G Y V+KA D G++VA+KK+ A D + REI +L+ +PN+I+L Sbjct: 19 RLGKGAYGIVWKAMDRRTGEVVAIKKIFDAFRDQIDAQRTFREIMLLKEFGGHPNIIRLL 78 Query: 416 GLVTSRMSSSLYLVFEYMEHDLAGLAATPGIKFTEAQVKCYMQQLL 553 ++ ++ +YLVFE M+ DL G + +C QLL Sbjct: 79 DVIPAKNDRDIYLVFESMDTDL-NAVIQKGRLLKDIHKRCIFYQLL 123
>PHO85_CANGA (Q6FKD4) Negative regulator of the PHO system (EC 2.7.11.22)| (Serine/threonine-protein kinase PHO85) Length = 302 Score = 59.7 bits (143), Expect = 5e-09 Identities = 31/89 (34%), Positives = 56/89 (62%) Frame = +2 Query: 215 AESFEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRFMAREIHILRRLDN 394 + F++L+K+G GTY++VYK + G VALK+V+ + + + REI +++ L + Sbjct: 3 SSQFKQLEKLGNGTYATVYKGLNKSTGVYVALKEVKL-DSEEGTPSTAIREISLMKELKH 61 Query: 395 PNVIKLEGLVTSRMSSSLYLVFEYMEHDL 481 N+++L ++ + L LVFEYM++DL Sbjct: 62 DNIVRLYDVI--HTENKLTLVFEYMDNDL 88
>CDKL2_RAT (Q5XIT0) Cyclin-dependent kinase-like 2 (EC 2.7.11.22)| Length = 507 Score = 59.7 bits (143), Expect = 5e-09 Identities = 38/116 (32%), Positives = 66/116 (56%), Gaps = 2/116 (1%) Frame = +2 Query: 218 ESFEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRFMAREIHILRRLDNP 397 E +E L +G+G+Y V K R+ ++G+IVA+KK ++ D + REI +L++L + Sbjct: 2 EKYENLGLVGEGSYGMVMKCRNKDSGRIVAIKKFLESDDDKMVKKIAMREIKLLKQLRHE 61 Query: 398 NVIKLEGLVTSRMSSSLYLVFEYMEHD-LAGLAATP-GIKFTEAQVKCYMQQLLSG 559 N++ L L + YLVFE+++H L L P G+ + Q Y+ Q+++G Sbjct: 62 NLVNL--LEVCKKKKRWYLVFEFVDHTILDDLKLFPNGLDYQVVQK--YLFQIING 113
>MOK_HUMAN (Q9UQ07) MAPK/MAK/MRK overlapping kinase (EC 2.7.11.22) (MOK| protein kinase) (Renal tumor antigen 1) (RAGE-1) Length = 419 Score = 59.7 bits (143), Expect = 5e-09 Identities = 38/112 (33%), Positives = 63/112 (56%), Gaps = 1/112 (0%) Frame = +2 Query: 218 ESFEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRFMAREIHILRRLD-N 394 ++++ + KIG+GT+S V K + L +G A K+++ E V + REI LRRL+ + Sbjct: 2 KNYKAIGKIGEGTFSEVMKMQSLRDGNYYACKQMKQRFESIEQVNNL-REIQALRRLNPH 60 Query: 395 PNVIKLEGLVTSRMSSSLYLVFEYMEHDLAGLAATPGIKFTEAQVKCYMQQL 550 PN++ L +V R S SL L+ E M+ ++ L +E ++ YM QL Sbjct: 61 PNILMLHEVVFDRKSGSLALICELMDMNIYELIRGRRYPLSEKKIMHYMYQL 112
>CDKL2_MACFA (Q4R7T5) Cyclin-dependent kinase-like 2 (EC 2.7.11.22)| Length = 570 Score = 59.3 bits (142), Expect = 7e-09 Identities = 38/116 (32%), Positives = 65/116 (56%), Gaps = 2/116 (1%) Frame = +2 Query: 218 ESFEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRFMAREIHILRRLDNP 397 E +E L +G+G+Y V K R+ + G+IVA+KK ++ D + REI +L++L + Sbjct: 2 EKYENLGLVGEGSYGMVVKCRNKDTGRIVAIKKFLESDDDKMVKKIAMREIKLLKQLRHE 61 Query: 398 NVIKLEGLVTSRMSSSLYLVFEYMEHD-LAGLAATP-GIKFTEAQVKCYMQQLLSG 559 N++ L L + YLVFE+++H L L P G+ + Q Y+ Q+++G Sbjct: 62 NLVNL--LEVCKKKKRWYLVFEFVDHTILDDLELFPNGLDYQVVQK--YLFQIING 113
>CDKL2_PONPY (Q5R754) Cyclin-dependent kinase-like 2 (EC 2.7.11.22)| Length = 493 Score = 59.3 bits (142), Expect = 7e-09 Identities = 38/116 (32%), Positives = 65/116 (56%), Gaps = 2/116 (1%) Frame = +2 Query: 218 ESFEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRFMAREIHILRRLDNP 397 E +E L +G+G+Y V K R+ + G+IVA+KK ++ D + REI +L++L + Sbjct: 2 EKYENLGLVGEGSYGMVMKCRNKDTGRIVAIKKFLESDDDKMVKKIAMREIKLLKQLRHE 61 Query: 398 NVIKLEGLVTSRMSSSLYLVFEYMEHD-LAGLAATP-GIKFTEAQVKCYMQQLLSG 559 N++ L L + YLVFE+++H L L P G+ + Q Y+ Q+++G Sbjct: 62 NLVNL--LEVCKKKKRWYLVFEFVDHTILDDLELFPNGLDYQVVQK--YLFQIING 113
>CDKL2_HUMAN (Q92772) Cyclin-dependent kinase-like 2 (EC 2.7.11.22)| (Serine/threonine-protein kinase KKIAMRE) (Protein kinase p56 KKIAMRE) Length = 493 Score = 59.3 bits (142), Expect = 7e-09 Identities = 38/116 (32%), Positives = 65/116 (56%), Gaps = 2/116 (1%) Frame = +2 Query: 218 ESFEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRFMAREIHILRRLDNP 397 E +E L +G+G+Y V K R+ + G+IVA+KK ++ D + REI +L++L + Sbjct: 2 EKYENLGLVGEGSYGMVMKCRNKDTGRIVAIKKFLESDDDKMVKKIAMREIKLLKQLRHE 61 Query: 398 NVIKLEGLVTSRMSSSLYLVFEYMEHD-LAGLAATP-GIKFTEAQVKCYMQQLLSG 559 N++ L L + YLVFE+++H L L P G+ + Q Y+ Q+++G Sbjct: 62 NLVNL--LEVCKKKKRWYLVFEFVDHTILDDLELFPNGLDYQVVQK--YLFQIING 113
>CRK1_SCHPO (Q12126) Serine/threonine-protein kinase crk1 (EC 2.7.11.23)| (Mitotic catastrophe suppressor 6) Length = 335 Score = 58.9 bits (141), Expect = 9e-09 Identities = 36/113 (31%), Positives = 60/113 (53%) Frame = +2 Query: 221 SFEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRFMAREIHILRRLDNPN 400 ++ K K+G+GTY+ V+ R E + VA+KK++ REI LR + N Sbjct: 10 TYVKERKVGEGTYAVVFLGRQKETNRRVAIKKIKVGQFKDGIDISALREIKFLRESRHDN 69 Query: 401 VIKLEGLVTSRMSSSLYLVFEYMEHDLAGLAATPGIKFTEAQVKCYMQQLLSG 559 VI+L + +++ S+L ++ E+++ DL L I F A +K +M LL G Sbjct: 70 VIELVDVFSTK--SNLNIILEFLDSDLEMLIKDKFIVFQPAHIKSWMVMLLRG 120
>MK06_RAT (P27704) Mitogen-activated protein kinase 6 (EC 2.7.11.24)| (Extracellular signal-regulated kinase 3) (ERK-3) (p55-MAPK) Length = 720 Score = 57.8 bits (138), Expect = 2e-08 Identities = 42/121 (34%), Positives = 63/121 (52%), Gaps = 12/121 (9%) Frame = +2 Query: 233 LDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRFMAREIHILRRLDNPNVIKL 412 L +G G V+ A D + K VA+KK+ DP+SV+ REI I+RRLD+ N++K+ Sbjct: 23 LKPLGCGGNGLVFSAVDNDCDKRVAIKKIVLT--DPQSVKHALREIKIIRRLDHDNIVKV 80 Query: 413 EGLVTSRMS------------SSLYLVFEYMEHDLAGLAATPGIKFTEAQVKCYMQQLLS 556 ++ S +S+Y+V EYME DLA + + E + +M QLL Sbjct: 81 FEILGPSGSQLTDDVGSLTELNSVYIVQEYMETDLANVLEQGPL--LEEHARLFMYQLLR 138 Query: 557 G 559 G Sbjct: 139 G 139
>MK06_MOUSE (Q61532) Mitogen-activated protein kinase 6 (EC 2.7.11.24)| (Extracellular signal-regulated kinase 3) (ERK-3) Length = 720 Score = 57.8 bits (138), Expect = 2e-08 Identities = 42/121 (34%), Positives = 63/121 (52%), Gaps = 12/121 (9%) Frame = +2 Query: 233 LDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRFMAREIHILRRLDNPNVIKL 412 L +G G V+ A D + K VA+KK+ DP+SV+ REI I+RRLD+ N++K+ Sbjct: 23 LKPLGCGGNGLVFSAVDNDCDKRVAIKKIVLT--DPQSVKHALREIKIIRRLDHDNIVKV 80 Query: 413 EGLVTSRMS------------SSLYLVFEYMEHDLAGLAATPGIKFTEAQVKCYMQQLLS 556 ++ S +S+Y+V EYME DLA + + E + +M QLL Sbjct: 81 FEILGPSGSQLTDDVGSLTELNSVYIVQEYMETDLANVLEQGPL--LEEHARLFMYQLLR 138 Query: 557 G 559 G Sbjct: 139 G 139
>YPC2_CAEEL (Q11179) Putative serine/threonine-protein kinase C05D10.2 in| chromosome III (EC 2.7.11.24) Length = 470 Score = 57.8 bits (138), Expect = 2e-08 Identities = 33/89 (37%), Positives = 50/89 (56%), Gaps = 1/89 (1%) Frame = +2 Query: 218 ESFEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRFMAREIHILRRL-DN 394 E F+ ++G+G Y V+KA D + + VALKK+ A +P + RE+ L+ + Sbjct: 11 EKFDLQKRLGKGAYGIVWKAYDKRSRETVALKKIFDAFRNPTDSQRTFREVMFLQEFGKH 70 Query: 395 PNVIKLEGLVTSRMSSSLYLVFEYMEHDL 481 PNVIKL + + +YL FE+ME DL Sbjct: 71 PNVIKLYNIFRADNDRDIYLAFEFMEADL 99
>MK06_HUMAN (Q16659) Mitogen-activated protein kinase 6 (EC 2.7.11.24)| (Extracellular signal-regulated kinase 3) (ERK-3) (MAP kinase isoform p97) (p97-MAPK) Length = 721 Score = 57.8 bits (138), Expect = 2e-08 Identities = 42/121 (34%), Positives = 63/121 (52%), Gaps = 12/121 (9%) Frame = +2 Query: 233 LDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRFMAREIHILRRLDNPNVIKL 412 L +G G V+ A D + K VA+KK+ DP+SV+ REI I+RRLD+ N++K+ Sbjct: 23 LKPLGCGGNGLVFSAVDNDCDKRVAIKKIVLT--DPQSVKHALREIKIIRRLDHDNIVKV 80 Query: 413 EGLVTSRMS------------SSLYLVFEYMEHDLAGLAATPGIKFTEAQVKCYMQQLLS 556 ++ S +S+Y+V EYME DLA + + E + +M QLL Sbjct: 81 FEILGPSGSQLTDDVGSLTELNSVYIVQEYMETDLANVLEQGPL--LEEHARLFMYQLLR 138 Query: 557 G 559 G Sbjct: 139 G 139
>PHO85_YEAST (P17157) Negative regulator of the PHO system (EC 2.7.11.22)| (Serine/threonine-protein kinase PHO85) Length = 305 Score = 57.8 bits (138), Expect = 2e-08 Identities = 30/89 (33%), Positives = 56/89 (62%) Frame = +2 Query: 215 AESFEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRFMAREIHILRRLDN 394 + F++L+K+G GTY++VYK + G VALK+V+ + + + REI +++ L + Sbjct: 4 SSQFKQLEKLGNGTYATVYKGLNKTTGVYVALKEVKL-DSEEGTPSTAIREISLMKELKH 62 Query: 395 PNVIKLEGLVTSRMSSSLYLVFEYMEHDL 481 N+++L ++ + L LVFE+M++DL Sbjct: 63 ENIVRLYDVI--HTENKLTLVFEFMDNDL 89
>STK4_HUMAN (Q13043) Serine/threonine-protein kinase 4 (EC 2.7.11.1)| (STE20-like kinase MST1) (MST-1) (Mammalian STE20-like protein kinase 1) (Serine/threonine-protein kinase Krs-2) Length = 487 Score = 57.8 bits (138), Expect = 2e-08 Identities = 36/115 (31%), Positives = 66/115 (57%), Gaps = 1/115 (0%) Frame = +2 Query: 218 ESFEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRFMAREIHILRRLDNP 397 E F+ L+K+G+G+Y SVYKA E G+IVA+K+V + ++ + +EI I+++ D+P Sbjct: 28 EVFDVLEKLGEGSYGSVYKAIHKETGQIVAIKQVPVES----DLQEIIKEISIMQQCDSP 83 Query: 398 NVIKLEGLVTSRMSSSLYLVFEYM-EHDLAGLAATPGIKFTEAQVKCYMQQLLSG 559 +V+K G + ++ L++V EY ++ + TE ++ +Q L G Sbjct: 84 HVVKYYG--SYFKNTDLWIVMEYCGAGSVSDIIRLRNKTLTEDEIATILQSTLKG 136
>CDK4_HUMAN (P11802) Cell division protein kinase 4 (EC 2.7.11.22)| (Cyclin-dependent kinase 4) (PSK-J3) Length = 303 Score = 57.4 bits (137), Expect = 3e-08 Identities = 47/125 (37%), Positives = 65/125 (52%), Gaps = 13/125 (10%) Frame = +2 Query: 224 FEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMD------PESVRFMAREIHILRR 385 +E + +IG G Y +VYKARD +G VALK VR N P S RE+ +LRR Sbjct: 6 YEPVAEIGVGAYGTVYKARDPHSGHFVALKSVRVPNGGGGGGGLPIST---VREVALLRR 62 Query: 386 L---DNPNVIKL-EGLVTSRMSSSL--YLVFEYMEHDL-AGLAATPGIKFTEAQVKCYMQ 544 L ++PNV++L + TSR + LVFE+++ DL L P +K M+ Sbjct: 63 LEAFEHPNVVRLMDVCATSRTDREIKVTLVFEHVDQDLRTYLDKAPPPGLPAETIKDLMR 122 Query: 545 QLLSG 559 Q L G Sbjct: 123 QFLRG 127
>PHO85_KLULA (Q92241) Negative regulator of the PHO system (EC 2.7.11.22)| (Serine/threonine-protein kinase PHO85) Length = 304 Score = 57.4 bits (137), Expect = 3e-08 Identities = 30/86 (34%), Positives = 55/86 (63%) Frame = +2 Query: 224 FEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRFMAREIHILRRLDNPNV 403 F++L+K+G GTY++VYK + G VALK+V+ + + + REI +++ L + N+ Sbjct: 7 FKQLEKVGNGTYATVYKGLNKTTGVYVALKEVKL-DSEEGTPSTAIREISLMKELKHDNI 65 Query: 404 IKLEGLVTSRMSSSLYLVFEYMEHDL 481 ++L ++ + L LVFE+M++DL Sbjct: 66 VRLFDVI--HTENKLTLVFEFMDNDL 89
>CDK4_PIG (P79432) Cell division protein kinase 4 (EC 2.7.11.22)| (Cyclin-dependent kinase 4) Length = 303 Score = 56.6 bits (135), Expect = 5e-08 Identities = 45/124 (36%), Positives = 66/124 (53%), Gaps = 12/124 (9%) Frame = +2 Query: 224 FEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRF---MAREIHILRRL-- 388 +E + +IG G Y +VYKARD +G VALK VR N RE+ +LRRL Sbjct: 6 YEPVAEIGVGAYGTVYKARDPHSGHFVALKSVRVPNGGGAGGGLPISTVREVALLRRLEA 65 Query: 389 -DNPNVIKL-EGLVTSR--MSSSLYLVFEYMEHDL---AGLAATPGIKFTEAQVKCYMQQ 547 ++PNV++L + T+R + + LVFE+++ DL A PG+ +K M+Q Sbjct: 66 FEHPNVVRLMDVCATARTDRETKVTLVFEHVDQDLRTYLDKAPPPGLPV--ETIKDLMRQ 123 Query: 548 LLSG 559 L G Sbjct: 124 FLRG 127
>STK36_PONPY (Q5RAJ5) Serine/threonine-protein kinase 36 (EC 2.7.11.1) (Fused| homolog) Length = 1315 Score = 56.6 bits (135), Expect = 5e-08 Identities = 35/113 (30%), Positives = 60/113 (53%) Frame = +2 Query: 218 ESFEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRFMAREIHILRRLDNP 397 E + L+ IG+G++ VYK R + ++VALK + + +R + REI I+R L +P Sbjct: 2 EKYHVLEMIGEGSFGRVYKGRRKYSAQVVALKFIPKLGRSEKELRNLQREIEIMRGLRHP 61 Query: 398 NVIKLEGLVTSRMSSSLYLVFEYMEHDLAGLAATPGIKFTEAQVKCYMQQLLS 556 N++ + L + + +V +Y E +L + G K E QV+ QL+S Sbjct: 62 NIVHM--LDSFETDKEVVVVTDYAEGELLQILEDDG-KLPEDQVQAIAAQLVS 111
>PHO85_ASHGO (Q751E8) Negative regulator of the PHO system (EC 2.7.11.22)| (Serine/threonine-protein kinase PHO85) Length = 303 Score = 56.2 bits (134), Expect = 6e-08 Identities = 29/86 (33%), Positives = 55/86 (63%) Frame = +2 Query: 224 FEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRFMAREIHILRRLDNPNV 403 F++L+++G GTY++VYK + G VALK+V+ + + + REI +++ L + N+ Sbjct: 9 FKQLERLGNGTYATVYKGLNKTTGLYVALKEVKL-DSEEGTPSTAIREISLMKELKHENI 67 Query: 404 IKLEGLVTSRMSSSLYLVFEYMEHDL 481 ++L ++ + L LVFE+M++DL Sbjct: 68 VRLYDVI--HTENKLTLVFEFMDNDL 91
>STK36_HUMAN (Q9NRP7) Serine/threonine-protein kinase 36 (EC 2.7.11.1) (Fused| homolog) Length = 1315 Score = 56.2 bits (134), Expect = 6e-08 Identities = 35/113 (30%), Positives = 60/113 (53%) Frame = +2 Query: 218 ESFEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRFMAREIHILRRLDNP 397 E + L+ IG+G++ VYK R + ++VALK + + +R + REI I+R L +P Sbjct: 2 EKYHVLEMIGEGSFGRVYKGRRKYSAQVVALKFIPKLGRSEKELRNLQREIEIMRGLRHP 61 Query: 398 NVIKLEGLVTSRMSSSLYLVFEYMEHDLAGLAATPGIKFTEAQVKCYMQQLLS 556 N++ + L + + +V +Y E +L + G K E QV+ QL+S Sbjct: 62 NIVHM--LDSFETDKEVVVVTDYAEGELFQILEDDG-KLPEDQVQAIAAQLVS 111
>KIN28_YEAST (P06242) Serine/threonine-protein kinase KIN28 (EC 2.7.11.23)| Length = 306 Score = 56.2 bits (134), Expect = 6e-08 Identities = 33/112 (29%), Positives = 57/112 (50%) Frame = +2 Query: 224 FEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRFMAREIHILRRLDNPNV 403 + K K+G+GTY+ VY G+ +A+K+++ + RE+ L+ + +PNV Sbjct: 7 YTKEKKVGEGTYAVVYLGCQHSTGRKIAIKEIKTSEFKDGLDMSAIREVKYLQEMQHPNV 66 Query: 404 IKLEGLVTSRMSSSLYLVFEYMEHDLAGLAATPGIKFTEAQVKCYMQQLLSG 559 I+L + + +L LV E++ DL + I FT A +K +M L G Sbjct: 67 IELIDIFMA--YDNLNLVLEFLPTDLEVVIKDKSILFTPADIKAWMLMTLRG 116
>CDC15_YEAST (P27636) Cell division control protein 15 (EC 2.7.11.1)| Length = 974 Score = 56.2 bits (134), Expect = 6e-08 Identities = 36/117 (30%), Positives = 62/117 (52%), Gaps = 1/117 (0%) Frame = +2 Query: 212 KAESFEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRFMAREIHILRRLD 391 K+ + IG+G+Y VYKA + ++VA+K+V + N E + + EI +L+ L+ Sbjct: 21 KSVQYHLKQVIGRGSYGVVYKAINKHTDQVVAIKEVVYEN--DEELNDIMAEISLLKNLN 78 Query: 392 NPNVIKLEGLVTSRMSSSLYLVFEYMEH-DLAGLAATPGIKFTEAQVKCYMQQLLSG 559 + N++K G + R S LY++ EY + L L + +E + K Y+ Q L G Sbjct: 79 HNNIVKYHGFI--RKSYELYILLEYCANGSLRRLISRSSTGLSENESKTYVTQTLLG 133
>BUR1_ASHGO (Q75D46) Serine/threonine-protein kinase BUR1 (EC 2.7.11.22) (EC| 2.7.11.23) Length = 753 Score = 56.2 bits (134), Expect = 6e-08 Identities = 39/134 (29%), Positives = 66/134 (49%), Gaps = 21/134 (15%) Frame = +2 Query: 221 SFEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRFMAREIHILRRLDNPN 400 ++++ K+GQGT+ VY+ L + VA+KK+ + REI IL+RL++ N Sbjct: 55 NYKEEKKLGQGTFGEVYRGVHLATQRQVAMKKILVKTENDLFPITAQREITILKRLNHRN 114 Query: 401 VIKLEGLV---------------TSRMSS------SLYLVFEYMEHDLAGLAATPGIKFT 517 V++L +V +S+ S+ S Y++ YM DL+G+ P + Sbjct: 115 VVQLIEMVYDYPPAQNGAAYGQDSSQASASADTMKSFYMILPYMVADLSGILHNPRVTLE 174 Query: 518 EAQVKCYMQQLLSG 559 A +K M Q+L G Sbjct: 175 MADIKNMMLQILEG 188
>CDK8_DROME (Q9VT57) Cell division protein kinase 8 (EC 2.7.11.22) (EC| 2.7.11.23) (DmCdk8) Length = 454 Score = 55.8 bits (133), Expect = 8e-08 Identities = 38/117 (32%), Positives = 57/117 (48%), Gaps = 10/117 (8%) Frame = +2 Query: 239 KIGQGTYSSVYKAR--DLENGKIVALKKVRFANMDPESVRFMAREIHILRRLDNPNVIKL 412 K+G+GTY VYKA+ + +GK ALK++ + + REI +LR L + NVI L Sbjct: 26 KVGRGTYGHVYKAKWKETSDGKEYALKQIDGTGLSMSA----CREIALLRELKHQNVITL 81 Query: 413 EGLVTSRMSSSLYLVFEYMEHDL--------AGLAATPGIKFTEAQVKCYMQQLLSG 559 + S ++L+ +Y EHDL A A + VK + Q+L G Sbjct: 82 IRVFLSHNDRKVFLLIDYAEHDLWHIIKFHRAAKATKKQVVVPRGMVKSLLYQILDG 138
>STK36_MOUSE (Q69ZM6) Serine/threonine-protein kinase 36 (EC 2.7.11.1) (Fused| homolog) Length = 1268 Score = 55.8 bits (133), Expect = 8e-08 Identities = 35/113 (30%), Positives = 60/113 (53%) Frame = +2 Query: 218 ESFEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRFMAREIHILRRLDNP 397 E + L+ IG+G++ VYK R + ++VALK + + +R + REI I+R L +P Sbjct: 2 EKYHVLEMIGEGSFGRVYKGRKKYSAQVVALKFIPKLGRSEKELRNLQREIEIMRGLWHP 61 Query: 398 NVIKLEGLVTSRMSSSLYLVFEYMEHDLAGLAATPGIKFTEAQVKCYMQQLLS 556 N++ + L + + +V +Y E +L + G K E QV+ QL+S Sbjct: 62 NIVHM--LDSFETDKEVVVVTDYAEGELFQILEDDG-KLPEDQVQAIAAQLVS 111
>CDK2_ENTHI (Q04770) Cell division protein kinase 2 homolog (EC 2.7.11.22)| Length = 291 Score = 55.1 bits (131), Expect = 1e-07 Identities = 33/86 (38%), Positives = 46/86 (53%) Frame = +2 Query: 224 FEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRFMAREIHILRRLDNPNV 403 +EK ++G+GTY V KA D + VALKK++ D REI +L L +PNV Sbjct: 4 YEKKQQLGEGTYGVVCKAWDTVCNRYVALKKIKQEREDDGIPVTSVREIAVLLELKHPNV 63 Query: 404 IKLEGLVTSRMSSSLYLVFEYMEHDL 481 + L + LYLVFE+ + DL Sbjct: 64 VDLYDIYLE--DKFLYLVFEFCDEDL 87
>MARK4_MOUSE (Q8CIP4) MAP/microtubule affinity-regulating kinase 4 (EC 2.7.11.1)| Length = 752 Score = 54.7 bits (130), Expect = 2e-07 Identities = 27/82 (32%), Positives = 52/82 (63%) Frame = +2 Query: 221 SFEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRFMAREIHILRRLDNPN 400 ++ L IG+G ++ V AR + G+ VA+K + ++P S++ + RE+ I++ L++PN Sbjct: 58 NYRLLRTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPSSLQKLFREVRIMKGLNHPN 117 Query: 401 VIKLEGLVTSRMSSSLYLVFEY 466 ++KL ++ + +LYLV EY Sbjct: 118 IVKLFEVIET--EKTLYLVMEY 137
>MARK4_HUMAN (Q96L34) MAP/microtubule affinity-regulating kinase 4 (EC 2.7.11.1)| (MAP/microtubule affinity-regulating kinase-like 1) Length = 752 Score = 54.7 bits (130), Expect = 2e-07 Identities = 27/82 (32%), Positives = 52/82 (63%) Frame = +2 Query: 221 SFEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRFMAREIHILRRLDNPN 400 ++ L IG+G ++ V AR + G+ VA+K + ++P S++ + RE+ I++ L++PN Sbjct: 58 NYRLLRTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPSSLQKLFREVRIMKGLNHPN 117 Query: 401 VIKLEGLVTSRMSSSLYLVFEY 466 ++KL ++ + +LYLV EY Sbjct: 118 IVKLFEVIET--EKTLYLVMEY 137
>M3K4_MOUSE (O08648) Mitogen-activated protein kinase kinase kinase 4 (EC| 2.7.11.25) (MAPK/ERK kinase kinase 4) (MEK kinase 4) (MEKK 4) Length = 1597 Score = 53.9 bits (128), Expect = 3e-07 Identities = 27/109 (24%), Positives = 61/109 (55%) Frame = +2 Query: 224 FEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRFMAREIHILRRLDNPNV 403 +++ +KIG+G Y VY ++ G+++A+K++RF D ++++ A E+ I + +PN+ Sbjct: 1332 WQRGNKIGEGQYGKVYTCISVDTGELMAMKEIRFQPNDHKTIKETADELKIFEGIKHPNL 1391 Query: 404 IKLEGLVTSRMSSSLYLVFEYMEHDLAGLAATPGIKFTEAQVKCYMQQL 550 ++ G+ R +Y+ EY + + G++ E ++ Y +Q+ Sbjct: 1392 VRYFGVELHR--EEMYIFMEYCDEGTLEEVSRLGLQ--EHVIRLYTKQI 1436
>M3K4_HUMAN (Q9Y6R4) Mitogen-activated protein kinase kinase kinase 4 (EC| 2.7.11.25) (MAPK/ERK kinase kinase 4) (MEK kinase 4) (MEKK 4) (MAP three kinase 1) Length = 1607 Score = 53.9 bits (128), Expect = 3e-07 Identities = 27/109 (24%), Positives = 61/109 (55%) Frame = +2 Query: 224 FEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRFMAREIHILRRLDNPNV 403 +++ +KIG+G Y VY ++ G+++A+K++RF D ++++ A E+ I + +PN+ Sbjct: 1342 WQRGNKIGEGQYGKVYTCISVDTGELMAMKEIRFQPNDHKTIKETADELKIFEGIKHPNL 1401 Query: 404 IKLEGLVTSRMSSSLYLVFEYMEHDLAGLAATPGIKFTEAQVKCYMQQL 550 ++ G+ R +Y+ EY + + G++ E ++ Y +Q+ Sbjct: 1402 VRYFGVELHR--EEMYIFMEYCDEGTLEEVSRLGLQ--EHVIRLYSKQI 1446
>MARK3_HUMAN (P27448) MAP/microtubule affinity-regulating kinase 3 (EC 2.7.11.1)| (Cdc25C-associated protein kinase 1) (cTAK1) (C-TAK1) (Serine/threonine protein kinase p78) (Ser/Thr protein kinase PAR-1) (Protein kinase STK10) Length = 776 Score = 53.9 bits (128), Expect = 3e-07 Identities = 26/82 (31%), Positives = 52/82 (63%) Frame = +2 Query: 221 SFEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRFMAREIHILRRLDNPN 400 ++ L IG+G ++ V AR + G+ VA+K + ++P S++ + RE+ I++ L++PN Sbjct: 55 NYRLLKTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPTSLQKLFREVRIMKILNHPN 114 Query: 401 VIKLEGLVTSRMSSSLYLVFEY 466 ++KL ++ + +LYL+ EY Sbjct: 115 IVKLFEVIET--EKTLYLIMEY 134
>MK04_MOUSE (Q6P5G0) Mitogen-activated protein kinase 4 (EC 2.7.11.24)| (Extracellular signal-regulated kinase 4) (ERK-4) Length = 583 Score = 53.9 bits (128), Expect = 3e-07 Identities = 42/121 (34%), Positives = 60/121 (49%), Gaps = 9/121 (7%) Frame = +2 Query: 224 FEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRFMAREIHILRRLDNPNV 403 F +G G V A D + VA+KK+ + D S++ REI I+RRLD+ N+ Sbjct: 20 FIDFQPLGFGVNGLVLSATDSRACRKVAVKKIVLS--DARSMKHALREIKIIRRLDHDNI 77 Query: 404 IKLEGLVTSRMS---------SSLYLVFEYMEHDLAGLAATPGIKFTEAQVKCYMQQLLS 556 +K+ ++ + S S Y+V EYME DLA L + TE K +M QLL Sbjct: 78 VKVYEVLGPKGSDLQGELFKFSVAYIVQEYMETDLACLLEQGTL--TEDHAKLFMYQLLR 135 Query: 557 G 559 G Sbjct: 136 G 136
>MARK3_MOUSE (Q03141) MAP/microtubule affinity-regulating kinase 3 (EC 2.7.11.1)| (MPK-10) (ELKL motif kinase 2) Length = 753 Score = 53.9 bits (128), Expect = 3e-07 Identities = 26/82 (31%), Positives = 52/82 (63%) Frame = +2 Query: 221 SFEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRFMAREIHILRRLDNPN 400 ++ L IG+G ++ V AR + G+ VA+K + ++P S++ + RE+ I++ L++PN Sbjct: 55 NYRLLKTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPTSLQKLFREVRIMKILNHPN 114 Query: 401 VIKLEGLVTSRMSSSLYLVFEY 466 ++KL ++ + +LYL+ EY Sbjct: 115 IVKLFEVIET--EKTLYLIMEY 134
>MARK3_RAT (Q8VHF0) MAP/microtubule affinity-regulating kinase 3 (EC 2.7.11.1)| Length = 797 Score = 53.9 bits (128), Expect = 3e-07 Identities = 26/82 (31%), Positives = 52/82 (63%) Frame = +2 Query: 221 SFEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRFMAREIHILRRLDNPN 400 ++ L IG+G ++ V AR + G+ VA+K + ++P S++ + RE+ I++ L++PN Sbjct: 55 NYRLLKTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPTSLQKLFREVRIMKILNHPN 114 Query: 401 VIKLEGLVTSRMSSSLYLVFEY 466 ++KL ++ + +LYL+ EY Sbjct: 115 IVKLFEVIET--EKTLYLIMEY 134
>BUR1_KLULA (Q6CRA9) Serine/threonine-protein kinase BUR1 (EC 2.7.11.22) (EC| 2.7.11.23) Length = 645 Score = 53.5 bits (127), Expect = 4e-07 Identities = 39/142 (27%), Positives = 64/142 (45%), Gaps = 29/142 (20%) Frame = +2 Query: 221 SFEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRFMAREIHILRRLDNPN 400 ++ + +K+GQGT+ V+K L + VA+K++ REI IL+R+++ N Sbjct: 54 NYREEEKLGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPITAQREITILKRMNHKN 113 Query: 401 VIKLEGLV-----TSRMSSS------------------------LYLVFEYMEHDLAGLA 493 ++KL +V T + S+ +++ YM DL GL Sbjct: 114 IVKLIEIVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYMVSDLTGLL 173 Query: 494 ATPGIKFTEAQVKCYMQQLLSG 559 P ++F A VK M QLL G Sbjct: 174 HNPRVEFGMADVKNIMLQLLEG 195
>STK3_HUMAN (Q13188) Serine/threonine-protein kinase 3 (EC 2.7.11.1)| (STE20-like kinase MST2) (MST-2) (Mammalian STE20-like protein kinase 2) (Serine/threonine-protein kinase Krs-1) Length = 491 Score = 53.5 bits (127), Expect = 4e-07 Identities = 29/83 (34%), Positives = 55/83 (66%) Frame = +2 Query: 218 ESFEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRFMAREIHILRRLDNP 397 E F+ L+K+G+G+Y SV+KA E+G++VA+K+V + ++ + +EI I+++ D+P Sbjct: 25 EVFDVLEKLGEGSYGSVFKAIHKESGQVVAIKQVPVES----DLQEIIKEISIMQQCDSP 80 Query: 398 NVIKLEGLVTSRMSSSLYLVFEY 466 V+K G + ++ L++V EY Sbjct: 81 YVVKYYG--SYFKNTDLWIVMEY 101
>KSG7_ARATH (Q39011) Shaggy-related protein kinase eta (EC 2.7.11.1) (ASK-eta)| (BRASSINOSTEROID-INSENSITIVE 2) (ULTRACURVATA1) Length = 380 Score = 53.5 bits (127), Expect = 4e-07 Identities = 37/125 (29%), Positives = 65/125 (52%), Gaps = 6/125 (4%) Frame = +2 Query: 203 QPRKAESFEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRFMAREIHILR 382 +P++ S+ +G G++ V++A+ LE G+ VA+KKV + R+ RE+ ++R Sbjct: 33 EPKQTISYMAERVVGTGSFGIVFQAKCLETGETVAIKKVL------QDRRYKNRELQLMR 86 Query: 383 RLDNPNVIKLEGL---VTSRMSSSLYLVFEYMEHDLAGLA---ATPGIKFTEAQVKCYMQ 544 +D+PNV+ L+ TS+ L LV EY+ L + ++ + VK YM Sbjct: 87 VMDHPNVVCLKHCFFSTTSKDELFLNLVMEYVPESLYRVLKHYSSANQRMPLVYVKLYMY 146 Query: 545 QLLSG 559 Q+ G Sbjct: 147 QIFRG 151
>KSG5_ARATH (Q8VZD5) Shaggy-related protein kinase epsilon (EC 2.7.11.1)| (ASK-epsilon) Length = 410 Score = 53.5 bits (127), Expect = 4e-07 Identities = 34/101 (33%), Positives = 55/101 (54%), Gaps = 3/101 (2%) Frame = +2 Query: 176 VATEAVRGWQPRKAESFEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRF 355 V T + QP++ S+ +GQG++ V++A+ LE G+ VA+KKV + R+ Sbjct: 58 VTTIGGKNGQPKQTISYMAERIVGQGSFGIVFQAKCLETGETVAIKKVL------QDKRY 111 Query: 356 MAREIHILRRLDNPNVIKLEGL---VTSRMSSSLYLVFEYM 469 RE+ +R LD+PNV+ L+ T + L LV EY+ Sbjct: 112 KNRELQTMRLLDHPNVVSLKHCFFSTTEKDELYLNLVLEYV 152
>STK3_MOUSE (Q9JI10) Serine/threonine-protein kinase 3 (EC 2.7.11.1)| (STE20-like kinase MST2) (MST-2) (Mammalian STE20-like protein kinase 2) Length = 497 Score = 53.5 bits (127), Expect = 4e-07 Identities = 29/83 (34%), Positives = 55/83 (66%) Frame = +2 Query: 218 ESFEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRFMAREIHILRRLDNP 397 E F+ L+K+G+G+Y SV+KA E+G++VA+K+V + ++ + +EI I+++ D+P Sbjct: 25 EVFDVLEKLGEGSYGSVFKAIHKESGQVVAIKQVPVES----DLQEIIKEISIMQQCDSP 80 Query: 398 NVIKLEGLVTSRMSSSLYLVFEY 466 V+K G + ++ L++V EY Sbjct: 81 YVVKYYG--SYFKNTDLWIVMEY 101
>STK24_MOUSE (Q99KH8) Serine/threonine-protein kinase 24 (EC 2.7.11.1)| Length = 431 Score = 53.1 bits (126), Expect = 5e-07 Identities = 38/124 (30%), Positives = 64/124 (51%), Gaps = 3/124 (2%) Frame = +2 Query: 197 GWQPRKA---ESFEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRFMARE 367 G Q KA E F KL+KIG+G++ V+K D K+VA+K + + E + + +E Sbjct: 12 GMQNLKADPEELFTKLEKIGKGSFGEVFKGIDNRTQKVVAIKIIDLEEAEDE-IEDIQQE 70 Query: 368 IHILRRLDNPNVIKLEGLVTSRMSSSLYLVFEYMEHDLAGLAATPGIKFTEAQVKCYMQQ 547 I +L + D+P V K G + + L+++ EY+ A PG E Q+ +++ Sbjct: 71 ITVLSQCDSPYVTKYYG--SYLKDTKLWIIMEYLGGGSALDLLEPG-PLDEIQIATILRE 127 Query: 548 LLSG 559 +L G Sbjct: 128 ILKG 131
>MPH1_SCHPO (O94235) Serine/threonine-protein kinase mph1 (EC 2.7.12.2)| Length = 678 Score = 53.1 bits (126), Expect = 5e-07 Identities = 33/90 (36%), Positives = 48/90 (53%), Gaps = 1/90 (1%) Frame = +2 Query: 224 FEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRFMAREIHILRRLD-NPN 400 F KL +G+G S VY+ +N ++ ALK+V F N D +++ EI +LR+L N Sbjct: 316 FIKLGVVGKGGSSMVYRIFSPDNSRLYALKEVNFINADQTTIQGYKNEIALLRKLSGNDR 375 Query: 401 VIKLEGLVTSRMSSSLYLVFEYMEHDLAGL 490 +IKL + L +V E E DLA L Sbjct: 376 IIKLYAAEVNDTLGQLNMVMECGETDLANL 405
>MSK1_MEDSA (P51137) Glycogen synthase kinase-3 homolog MsK-1 (EC 2.7.11.1)| Length = 411 Score = 53.1 bits (126), Expect = 5e-07 Identities = 34/101 (33%), Positives = 54/101 (53%), Gaps = 3/101 (2%) Frame = +2 Query: 176 VATEAVRGWQPRKAESFEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRF 355 V T R QP++ S+ +G G++ V++A+ LE G+ VA+KKV + R+ Sbjct: 59 VTTIGGRNGQPKQTISYMAERVVGHGSFGVVFQAKCLETGETVAIKKVL------QDKRY 112 Query: 356 MAREIHILRRLDNPNVIKLEGL---VTSRMSSSLYLVFEYM 469 RE+ +R LD+PNV+ L+ T + L LV EY+ Sbjct: 113 KNRELQTMRLLDHPNVVSLKHCFFSTTEKDELYLNLVLEYV 153
>STK24_HUMAN (Q9Y6E0) Serine/threonine-protein kinase 24 (EC 2.7.11.1)| (STE20-like kinase MST3) (MST-3) (Mammalian STE20-like protein kinase 3) Length = 443 Score = 53.1 bits (126), Expect = 5e-07 Identities = 34/114 (29%), Positives = 60/114 (52%) Frame = +2 Query: 218 ESFEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRFMAREIHILRRLDNP 397 E F KL+KIG+G++ V+K D K+VA+K + + E + + +EI +L + D+P Sbjct: 34 ELFTKLEKIGKGSFGEVFKGIDNRTQKVVAIKIIDLEEAEDE-IEDIQQEITVLSQCDSP 92 Query: 398 NVIKLEGLVTSRMSSSLYLVFEYMEHDLAGLAATPGIKFTEAQVKCYMQQLLSG 559 V K G + + L+++ EY+ A PG E Q+ ++++L G Sbjct: 93 YVTKYYG--SYLKDTKLWIIMEYLGGGSALDLLEPG-PLDETQIATILREILKG 143
>KSG1_ARATH (P43288) Shaggy-related protein kinase alpha (EC 2.7.11.1)| (ASK-alpha) Length = 405 Score = 52.8 bits (125), Expect = 7e-07 Identities = 34/101 (33%), Positives = 54/101 (53%), Gaps = 3/101 (2%) Frame = +2 Query: 176 VATEAVRGWQPRKAESFEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRF 355 V T R QP++ S+ +G G++ V++A+ LE G+ VA+KKV + R+ Sbjct: 53 VTTIGGRNGQPKQTISYMAERVVGHGSFGVVFQAKCLETGETVAIKKVL------QDRRY 106 Query: 356 MAREIHILRRLDNPNVIKLEGL---VTSRMSSSLYLVFEYM 469 RE+ +R LD+PNV+ L+ T + L LV EY+ Sbjct: 107 KNRELQTMRLLDHPNVVSLKHCFFSTTEKDELYLNLVLEYV 147
>CDKL3_RAT (Q9JM01) Cyclin-dependent kinase-like 3 (EC 2.7.11.22)| (Serine/threonine protein kinase NKIATRE) Length = 593 Score = 52.8 bits (125), Expect = 7e-07 Identities = 26/86 (30%), Positives = 50/86 (58%) Frame = +2 Query: 218 ESFEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRFMAREIHILRRLDNP 397 E +E L K+G+G+Y +V K + + G+IVA+ K+ + + + REI L++ + Sbjct: 2 EMYETLGKVGEGSYGTVMKCKHKDTGRIVAI-KIFYEKPEKSVNKIATREIKFLKQFRHE 60 Query: 398 NVIKLEGLVTSRMSSSLYLVFEYMEH 475 N++ L + R ++LVFE+++H Sbjct: 61 NLVNL--IEVFRQKKKIHLVFEFIDH 84
>MSK1_TOBAC (Q40518) Shaggy-related protein kinase NtK-1 (EC 2.7.11.1)| Length = 409 Score = 52.8 bits (125), Expect = 7e-07 Identities = 35/101 (34%), Positives = 55/101 (54%), Gaps = 3/101 (2%) Frame = +2 Query: 176 VATEAVRGWQPRKAESFEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRF 355 V T R QP++ S+ +GQG++ V++A+ LE G+ VA+KKV + R+ Sbjct: 57 VTTIGGRHGQPKQTISYMAERIVGQGSFGVVFQAKCLETGETVAIKKVL------QDKRY 110 Query: 356 MAREIHILRRLDNPNVIKLEGL---VTSRMSSSLYLVFEYM 469 RE+ +R LD+PNV+ L+ T + L LV EY+ Sbjct: 111 KNRELQTMRLLDHPNVVCLKHCFFSTTEKDEVYLNLVLEYV 151
>KSG3_ARATH (P43289) Shaggy-related protein kinase gamma (EC 2.7.11.1)| (ASK-gamma) Length = 409 Score = 52.8 bits (125), Expect = 7e-07 Identities = 34/101 (33%), Positives = 54/101 (53%), Gaps = 3/101 (2%) Frame = +2 Query: 176 VATEAVRGWQPRKAESFEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRF 355 V T R QP++ S+ +G G++ V++A+ LE G+ VA+KKV + R+ Sbjct: 57 VTTIGGRNGQPKQTISYMAERVVGHGSFGVVFQAKCLETGETVAIKKVL------QDRRY 110 Query: 356 MAREIHILRRLDNPNVIKLEGL---VTSRMSSSLYLVFEYM 469 RE+ +R LD+PNV+ L+ T + L LV EY+ Sbjct: 111 KNRELQTMRLLDHPNVVSLKHCFFSTTEKDELYLNLVLEYV 151
>KSG9_ARATH (Q39012) Shaggy-related protein kinase iota (EC 2.7.11.1)| (ASK-iota) Length = 407 Score = 52.8 bits (125), Expect = 7e-07 Identities = 33/96 (34%), Positives = 54/96 (56%), Gaps = 3/96 (3%) Frame = +2 Query: 203 QPRKAESFEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRFMAREIHILR 382 +P++ S+ +G G++ V++A+ LE G+ VA+KKV + R+ RE+ ++R Sbjct: 63 EPKQTISYMAERVVGTGSFGIVFQAKCLETGESVAIKKVL------QDRRYKNRELQLMR 116 Query: 383 RLDNPNVIKLEGL---VTSRMSSSLYLVFEYMEHDL 481 +D+PNVI L+ TSR L LV EY+ L Sbjct: 117 PMDHPNVISLKHCFFSTTSRDELFLNLVMEYVPETL 152
>CDKL3_MOUSE (Q8BLF2) Cyclin-dependent kinase-like 3 (EC 2.7.11.22)| Length = 595 Score = 52.8 bits (125), Expect = 7e-07 Identities = 26/86 (30%), Positives = 50/86 (58%) Frame = +2 Query: 218 ESFEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRFMAREIHILRRLDNP 397 E +E L K+G+G+Y +V K + + G+IVA+ K+ + + + REI L++ + Sbjct: 2 EMYETLGKVGEGSYGTVMKCKHKDTGRIVAI-KIFYEKPEKSVNKIATREIKFLKQFRHE 60 Query: 398 NVIKLEGLVTSRMSSSLYLVFEYMEH 475 N++ L + R ++LVFE+++H Sbjct: 61 NLVNL--IEVFRQKKKIHLVFEFIDH 84
>MK04_RAT (Q63454) Mitogen-activated protein kinase 4 (EC 2.7.11.24)| (Extracellular signal-regulated kinase 4) (ERK-4) (MAP kinase isoform p63) (p63-MAPK) (MNK2) (Fragment) Length = 274 Score = 52.4 bits (124), Expect = 9e-07 Identities = 41/114 (35%), Positives = 58/114 (50%), Gaps = 9/114 (7%) Frame = +2 Query: 245 GQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRFMAREIHILRRLDNPNVIKLEGLV 424 G G V A D + VA+KK+ + D S++ REI I+RRLD+ N++K+ ++ Sbjct: 1 GCGGNGLVLSATDSRACRKVAVKKIVLS--DARSMKHALREIKIIRRLDHDNIVKVYEVL 58 Query: 425 TSRMS---------SSLYLVFEYMEHDLAGLAATPGIKFTEAQVKCYMQQLLSG 559 + S S Y+V EYME DLA L + TE K +M QLL G Sbjct: 59 GPKGSDLQGELFKFSVAYIVQEYMETDLACLLEQGTL--TEEHAKLFMYQLLRG 110
>MSK2_MEDSA (P51138) Glycogen synthase kinase-3 homolog MsK-2 (EC 2.7.11.1)| Length = 411 Score = 52.4 bits (124), Expect = 9e-07 Identities = 33/101 (32%), Positives = 55/101 (54%), Gaps = 3/101 (2%) Frame = +2 Query: 176 VATEAVRGWQPRKAESFEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRF 355 V T + QP++ S+ +GQG++ V++A+ LE G+ VA+KKV + R+ Sbjct: 58 VTTIGGKNGQPKQTISYMAERAVGQGSFGVVFQAKCLETGETVAIKKVL------QDKRY 111 Query: 356 MAREIHILRRLDNPNVIKLEGL---VTSRMSSSLYLVFEYM 469 RE+ +R LD+PNV+ L+ T + L LV E++ Sbjct: 112 KNRELQTMRLLDHPNVVTLKHCFFSTTEKDELYLNLVLEFV 152
>MARK2_HUMAN (Q7KZI7) Serine/threonine-protein kinase MARK2 (EC 2.7.11.1)| (MAP/microtubule affinity-regulating kinase 2) (ELKL motif kinase) (EMK1) (PAR1 homolog) Length = 788 Score = 52.4 bits (124), Expect = 9e-07 Identities = 27/82 (32%), Positives = 51/82 (62%) Frame = +2 Query: 221 SFEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRFMAREIHILRRLDNPN 400 ++ L IG+G ++ V AR + GK VA+K + ++ S++ + RE+ I++ L++PN Sbjct: 52 NYRLLKTIGKGNFAKVKLARHILTGKEVAVKIIDKTQLNSSSLQKLFREVRIMKVLNHPN 111 Query: 401 VIKLEGLVTSRMSSSLYLVFEY 466 ++KL ++ + +LYLV EY Sbjct: 112 IVKLFEVIET--EKTLYLVMEY 131
>MARK2_MOUSE (Q05512) Serine/threonine-protein kinase MARK2 (EC 2.7.11.1)| (MAP/microtubule affinity-regulating kinase 2) (ELKL Motif Kinase) (EMK1) Length = 776 Score = 52.4 bits (124), Expect = 9e-07 Identities = 27/82 (32%), Positives = 51/82 (62%) Frame = +2 Query: 221 SFEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRFMAREIHILRRLDNPN 400 ++ L IG+G ++ V AR + GK VA+K + ++ S++ + RE+ I++ L++PN Sbjct: 52 NYRLLKTIGKGNFAKVKLARHILTGKEVAVKIIDKTQLNSSSLQKLFREVRIMKVLNHPN 111 Query: 401 VIKLEGLVTSRMSSSLYLVFEY 466 ++KL ++ + +LYLV EY Sbjct: 112 IVKLFEVIET--EKTLYLVMEY 131
>MKK1_YEAST (P32490) MAP kinase kinase MKK1/SSP32 (EC 2.7.12.2)| Length = 508 Score = 52.4 bits (124), Expect = 9e-07 Identities = 29/92 (31%), Positives = 46/92 (50%), Gaps = 1/92 (1%) Frame = +2 Query: 197 GWQ-PRKAESFEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRFMAREIH 373 GW+ + E L +G+G SV K + KI ALK + N DPE + + RE+ Sbjct: 211 GWKYANLKDRIETLGILGEGAGGSVSKCKLKNGSKIFALKVINTLNTDPEYQKQIFRELQ 270 Query: 374 ILRRLDNPNVIKLEGLVTSRMSSSLYLVFEYM 469 R + +++ G+ T +SS+Y+ EYM Sbjct: 271 FNRSFQSEYIVRYYGMFTDDENSSIYIAMEYM 302
>MARK2_RAT (O08679) Serine/threonine-protein kinase MARK2 (EC 2.7.11.1)| (MAP/microtubule affinity-regulating kinase 2) (ELKL Motif Kinase) (EMK1) Length = 722 Score = 52.4 bits (124), Expect = 9e-07 Identities = 27/82 (32%), Positives = 51/82 (62%) Frame = +2 Query: 221 SFEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRFMAREIHILRRLDNPN 400 ++ L IG+G ++ V AR + GK VA+K + ++ S++ + RE+ I++ L++PN Sbjct: 52 NYRLLKTIGKGNFAKVKLARHILTGKEVAVKIIDKTQLNSSSLQKLFREVRIMKVLNHPN 111 Query: 401 VIKLEGLVTSRMSSSLYLVFEY 466 ++KL ++ + +LYLV EY Sbjct: 112 IVKLFEVIET--EKTLYLVMEY 131
>MSK3_MEDSA (P51139) Glycogen synthase kinase-3 homolog MsK-3 (EC 2.7.11.1)| Length = 411 Score = 52.0 bits (123), Expect = 1e-06 Identities = 33/101 (32%), Positives = 54/101 (53%), Gaps = 3/101 (2%) Frame = +2 Query: 176 VATEAVRGWQPRKAESFEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRF 355 V T + QP++ S+ +G G++ V++A+ LE G+ VA+KKV + R+ Sbjct: 58 VTTIGGKNGQPKQTISYMAERVVGHGSFGVVFQAKCLETGETVAIKKVL------QDKRY 111 Query: 356 MAREIHILRRLDNPNVIKLEGL---VTSRMSSSLYLVFEYM 469 RE+ +R LD+PNV+ L+ T + L LV EY+ Sbjct: 112 KNRELQTMRLLDHPNVVSLKHCFFSTTEKDELYLNLVLEYV 152
>CDKL3_MACFA (Q4R8T9) Cyclin-dependent kinase-like 3 (EC 2.7.11.22)| Length = 590 Score = 52.0 bits (123), Expect = 1e-06 Identities = 30/87 (34%), Positives = 51/87 (58%), Gaps = 1/87 (1%) Frame = +2 Query: 218 ESFEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRFMA-REIHILRRLDN 394 E +E L K+G+G+Y +V K + G+IVA+K F +SV +A REI L++ + Sbjct: 2 EMYETLGKVGEGSYGTVMKCKHKNTGQIVAIK--IFYERPEQSVNKIAMREIKFLKQFHH 59 Query: 395 PNVIKLEGLVTSRMSSSLYLVFEYMEH 475 N++ L + R ++LVFE+++H Sbjct: 60 ENLVNL--IEVFRQKKKIHLVFEFIDH 84
>CDKL3_HUMAN (Q8IVW4) Cyclin-dependent kinase-like 3 (EC 2.7.11.22)| (Serine/threonine protein kinase NKIAMRE) Length = 592 Score = 52.0 bits (123), Expect = 1e-06 Identities = 30/87 (34%), Positives = 51/87 (58%), Gaps = 1/87 (1%) Frame = +2 Query: 218 ESFEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRFMA-REIHILRRLDN 394 E +E L K+G+G+Y +V K + G+IVA+K F +SV +A REI L++ + Sbjct: 2 EMYETLGKVGEGSYGTVMKCKHKNTGQIVAIK--IFYERPEQSVNKIAMREIKFLKQFHH 59 Query: 395 PNVIKLEGLVTSRMSSSLYLVFEYMEH 475 N++ L + R ++LVFE+++H Sbjct: 60 ENLVNL--IEVFRQKKKIHLVFEFIDH 84
>MARK1_MOUSE (Q8VHJ5) Serine/threonine-protein kinase MARK1 (EC 2.7.11.1)| (MAP/microtubule affinity-regulating kinase 1) (ELKL motif serine/threonine-protein kinase 3) Length = 795 Score = 52.0 bits (123), Expect = 1e-06 Identities = 26/75 (34%), Positives = 49/75 (65%) Frame = +2 Query: 242 IGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRFMAREIHILRRLDNPNVIKLEGL 421 IG+G ++ V AR + G+ VA+K + ++P S++ + RE+ I++ L++PN++KL + Sbjct: 66 IGKGNFAKVKLARHVLTGREVAVKIIDKTQLNPTSLQKLFREVRIMKILNHPNIVKLFEV 125 Query: 422 VTSRMSSSLYLVFEY 466 + + +LYLV EY Sbjct: 126 IET--EKTLYLVMEY 138
>MARK1_HUMAN (Q9P0L2) Serine/threonine-protein kinase MARK1 (EC 2.7.11.1)| (MAP/microtubule affinity-regulating kinase 1) Length = 795 Score = 52.0 bits (123), Expect = 1e-06 Identities = 26/75 (34%), Positives = 49/75 (65%) Frame = +2 Query: 242 IGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRFMAREIHILRRLDNPNVIKLEGL 421 IG+G ++ V AR + G+ VA+K + ++P S++ + RE+ I++ L++PN++KL + Sbjct: 66 IGKGNFAKVKLARHVLTGREVAVKIIDKTQLNPTSLQKLFREVRIMKILNHPNIVKLFEV 125 Query: 422 VTSRMSSSLYLVFEY 466 + + +LYLV EY Sbjct: 126 IET--EKTLYLVMEY 138
>MARK1_RAT (O08678) Serine/threonine-protein kinase MARK1 (EC 2.7.11.1)| (MAP/microtubule affinity-regulating kinase 1) Length = 793 Score = 52.0 bits (123), Expect = 1e-06 Identities = 26/75 (34%), Positives = 49/75 (65%) Frame = +2 Query: 242 IGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRFMAREIHILRRLDNPNVIKLEGL 421 IG+G ++ V AR + G+ VA+K + ++P S++ + RE+ I++ L++PN++KL + Sbjct: 66 IGKGNFAKVKLARHVLTGREVAVKIIDKTQLNPTSLQKLFREVRIMKILNHPNIVKLFEV 125 Query: 422 VTSRMSSSLYLVFEY 466 + + +LYLV EY Sbjct: 126 IET--EKTLYLVMEY 138
>MK04_HUMAN (P31152) Mitogen-activated protein kinase 4 (EC 2.7.11.24)| (Extracellular signal-regulated kinase 4) (ERK-4) (MAP kinase isoform p63) (p63-MAPK) Length = 557 Score = 52.0 bits (123), Expect = 1e-06 Identities = 40/121 (33%), Positives = 59/121 (48%), Gaps = 9/121 (7%) Frame = +2 Query: 224 FEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRFMAREIHILRRLDNPNV 403 F +G G V A D + VA+KK+ + D S++ REI I+RRLD+ N+ Sbjct: 20 FVDFQPLGFGVNGLVLSAVDSRACRKVAVKKIALS--DARSMKHALREIKIIRRLDHDNI 77 Query: 404 IKLEGLVTSRMS---------SSLYLVFEYMEHDLAGLAATPGIKFTEAQVKCYMQQLLS 556 +K+ ++ + + S Y+V EYME DLA L + E K +M QLL Sbjct: 78 VKVYEVLGPKGTDLQGELFKFSVAYIVQEYMETDLARLLEQGTL--AEEHAKLFMYQLLR 135 Query: 557 G 559 G Sbjct: 136 G 136
>GSK3A_RAT (P18265) Glycogen synthase kinase-3 alpha (EC 2.7.11.26) (GSK-3| alpha) (Factor A) (FA) Length = 483 Score = 51.6 bits (122), Expect = 1e-06 Identities = 43/139 (30%), Positives = 69/139 (49%), Gaps = 11/139 (7%) Frame = +2 Query: 167 LTEVATEAVRGWQPRKAESFEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPES 346 +T V +G + + ++ + IG G++ VY+AR E ++VA+KKV + Sbjct: 100 VTTVVATLGQGPERSQEVAYTDIKVIGNGSFGVVYQARLAETRELVAIKKVL------QD 153 Query: 347 VRFMAREIHILRRLDNPNVIKLEGLVTS--RMSSSLY--LVFEYMEHDLAGLAATPGIKF 514 RF RE+ I+R+LD+ N+++L S LY LV EY+ + +A F Sbjct: 154 KRFKNRELQIMRKLDHCNIVRLRYFFYSSGEKKDELYLNLVLEYVPETVYRVAR----HF 209 Query: 515 TEAQ-------VKCYMQQL 550 T+A+ VK YM QL Sbjct: 210 TKAKLIIPIIYVKVYMYQL 228
>GSK3A_HUMAN (P49840) Glycogen synthase kinase-3 alpha (EC 2.7.11.26) (GSK-3| alpha) Length = 483 Score = 51.6 bits (122), Expect = 1e-06 Identities = 43/139 (30%), Positives = 69/139 (49%), Gaps = 11/139 (7%) Frame = +2 Query: 167 LTEVATEAVRGWQPRKAESFEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPES 346 +T V +G + + ++ + IG G++ VY+AR E ++VA+KKV + Sbjct: 100 VTTVVATLGQGPERSQEVAYTDIKVIGNGSFGVVYQARLAETRELVAIKKVL------QD 153 Query: 347 VRFMAREIHILRRLDNPNVIKLEGLVTS--RMSSSLY--LVFEYMEHDLAGLAATPGIKF 514 RF RE+ I+R+LD+ N+++L S LY LV EY+ + +A F Sbjct: 154 KRFKNRELQIMRKLDHCNIVRLRYFFYSSGEKKDELYLNLVLEYVPETVYRVAR----HF 209 Query: 515 TEAQ-------VKCYMQQL 550 T+A+ VK YM QL Sbjct: 210 TKAKLTIPILYVKVYMYQL 228
>IKKE_MOUSE (Q9R0T8) Inhibitor of nuclear factor kappa-B kinase epsilon subunit| (EC 2.7.11.1) (I kappa-B kinase epsilon) (IkBKE) (IKK-epsilon) (IKK-E) (Inducible I kappa-B kinase) (IKK-i) Length = 717 Score = 51.6 bits (122), Expect = 1e-06 Identities = 30/78 (38%), Positives = 48/78 (61%), Gaps = 1/78 (1%) Frame = +2 Query: 236 DKIGQGTYSSVYKARDLENGKIVALKKVRFAN-MDPESVRFMAREIHILRRLDNPNVIKL 412 D +GQG +SVYKAR+ ++G++VA+K A+ P V+ RE +LRRL++ N++KL Sbjct: 13 DLLGQGATASVYKARNKKSGEVVAVKVFNSASYRRPPEVQ--VREFEVLRRLNHQNIVKL 70 Query: 413 EGLVTSRMSSSLYLVFEY 466 + + S L+ EY Sbjct: 71 FAVEETGGSRQKVLIMEY 88
>CSK2A_DICDI (Q02720) Casein kinase II subunit alpha (EC 2.7.11.1) (CK II alpha| subunit) Length = 337 Score = 51.6 bits (122), Expect = 1e-06 Identities = 35/114 (30%), Positives = 63/114 (55%), Gaps = 2/114 (1%) Frame = +2 Query: 218 ESFEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRFMAREIHILRRL-DN 394 + +E + KIG+G YS V++ +++N + +K ++ P + + REI IL+ L Sbjct: 45 DDYEIIRKIGRGKYSEVFEGANIKNNEKCVIKVLK-----PVKKKKIKREIKILQNLCGG 99 Query: 395 PNVIKLEGLVTSRMSSSLYLVFEYMEH-DLAGLAATPGIKFTEAQVKCYMQQLL 553 PN+I L +V S + L+FEY+ + D L+ T T+ V+ Y+++LL Sbjct: 100 PNIITLYDVVRDPQSKTPSLIFEYINNTDFKHLSPT----LTDFDVRYYIRELL 149
>NEK6_RAT (P59895) Serine/threonine-protein kinase Nek6 (EC 2.7.11.1)| (NimA-related protein kinase 6) Length = 313 Score = 51.6 bits (122), Expect = 1e-06 Identities = 29/63 (46%), Positives = 44/63 (69%), Gaps = 1/63 (1%) Frame = +2 Query: 224 FEKLDKIGQGTYSSVYKARDLENGKIVALKKVR-FANMDPESVRFMAREIHILRRLDNPN 400 F+ KIG+G +S VYKA L + K VALKKV+ F MD ++ + +EI +L++L++PN Sbjct: 45 FQIEKKIGRGQFSEVYKATCLLDRKTVALKKVQIFEMMDAKARQDCVKEIGLLKQLNHPN 104 Query: 401 VIK 409 +IK Sbjct: 105 IIK 107
>NEK6_MOUSE (Q9ES70) Serine/threonine-protein kinase Nek6 (EC 2.7.11.1)| (NimA-related protein kinase 6) Length = 313 Score = 51.6 bits (122), Expect = 1e-06 Identities = 29/63 (46%), Positives = 44/63 (69%), Gaps = 1/63 (1%) Frame = +2 Query: 224 FEKLDKIGQGTYSSVYKARDLENGKIVALKKVR-FANMDPESVRFMAREIHILRRLDNPN 400 F+ KIG+G +S VYKA L + K VALKKV+ F MD ++ + +EI +L++L++PN Sbjct: 45 FQIEKKIGRGQFSEVYKATCLLDRKTVALKKVQIFEMMDAKARQDCVKEIGLLKQLNHPN 104 Query: 401 VIK 409 +IK Sbjct: 105 IIK 107
>NEK6_HUMAN (Q9HC98) Serine/threonine-protein kinase Nek6 (EC 2.7.11.1)| (NimA-related protein kinase 6) (Protein kinase SID6-1512) Length = 313 Score = 51.6 bits (122), Expect = 1e-06 Identities = 29/63 (46%), Positives = 44/63 (69%), Gaps = 1/63 (1%) Frame = +2 Query: 224 FEKLDKIGQGTYSSVYKARDLENGKIVALKKVR-FANMDPESVRFMAREIHILRRLDNPN 400 F+ KIG+G +S VYKA L + K VALKKV+ F MD ++ + +EI +L++L++PN Sbjct: 45 FQIEKKIGRGQFSEVYKATCLLDRKTVALKKVQIFEMMDAKARQDCVKEIGLLKQLNHPN 104 Query: 401 VIK 409 +IK Sbjct: 105 IIK 107
>MPK3_ARATH (Q39023) Mitogen-activated protein kinase homolog 3 (EC 2.7.11.24)| (MAP kinase 3) (AtMPK3) Length = 370 Score = 51.2 bits (121), Expect = 2e-06 Identities = 34/109 (31%), Positives = 55/109 (50%), Gaps = 3/109 (2%) Frame = +2 Query: 242 IGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRFMAREIHILRRLDNPNVIKLEGL 421 IG+G Y V D E ++VA+KK+ A + + REI +LR LD+ N+I + + Sbjct: 44 IGRGAYGIVCSVLDTETNELVAMKKIANAFDNHMDAKRTLREIKLLRHLDHENIIAIRDV 103 Query: 422 V---TSRMSSSLYLVFEYMEHDLAGLAATPGIKFTEAQVKCYMQQLLSG 559 V R S +Y+ E M+ DL + + +E + ++ QLL G Sbjct: 104 VPPPLRRQFSDVYISTELMDTDLHQIIRS-NQSLSEEHCQYFLYQLLRG 151
>MKK2_YEAST (P32491) MAP kinase kinase MKK2/SSP33 (EC 2.7.12.2)| Length = 506 Score = 51.2 bits (121), Expect = 2e-06 Identities = 28/77 (36%), Positives = 44/77 (57%), Gaps = 1/77 (1%) Frame = +2 Query: 242 IGQGTYSSVYKARDLENGK-IVALKKVRFANMDPESVRFMAREIHILRRLDNPNVIKLEG 418 +G+G SV K R L+NGK + ALK + N DPE + + RE+ + + +++ G Sbjct: 220 LGEGAGGSVAKCR-LKNGKKVFALKTINTMNTDPEYQKQIFRELQFNKSFKSDYIVQYYG 278 Query: 419 LVTSRMSSSLYLVFEYM 469 + T SSS+Y+ EYM Sbjct: 279 MFTDEQSSSIYIAMEYM 295
>KSG6_ARATH (Q39010) Shaggy-related protein kinase dzeta (EC 2.7.11.1)| (ASK-dzeta) Length = 412 Score = 51.2 bits (121), Expect = 2e-06 Identities = 31/96 (32%), Positives = 54/96 (56%), Gaps = 3/96 (3%) Frame = +2 Query: 203 QPRKAESFEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRFMAREIHILR 382 +P++ S+ +G G++ V++A+ LE G+ VA+KKV + R+ RE+ ++R Sbjct: 65 EPKQTISYMAERVVGTGSFGIVFQAKCLETGESVAIKKVL------QDRRYKNRELQLMR 118 Query: 383 RLDNPNVIKLEGL---VTSRMSSSLYLVFEYMEHDL 481 +D+PNV+ L+ T+R L LV EY+ L Sbjct: 119 LMDHPNVVSLKHCFFSTTTRDELFLNLVMEYVPETL 154
>TAOK2_RAT (Q9JLS3) Serine/threonine-protein kinase TAO2 (EC 2.7.11.1)| (Thousand and one amino acid protein 2) Length = 1235 Score = 51.2 bits (121), Expect = 2e-06 Identities = 27/82 (32%), Positives = 49/82 (59%), Gaps = 1/82 (1%) Frame = +2 Query: 224 FEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFA-NMDPESVRFMAREIHILRRLDNPN 400 F L +IG G++ +VY ARD+ N ++VA+KK+ ++ E + + +E+ L++L +PN Sbjct: 28 FSDLREIGHGSFGAVYFARDVRNSEVVAIKKMSYSGKQSNEKWQDIIKEVRFLQKLRHPN 87 Query: 401 VIKLEGLVTSRMSSSLYLVFEY 466 I+ G ++ +LV EY Sbjct: 88 TIQYRGCYLREHTA--WLVMEY 107
>TAOK2_HUMAN (Q9UL54) Serine/threonine-protein kinase TAO2 (EC 2.7.11.1)| (Thousand and one amino acid protein 2) (Prostate-derived STE20-like kinase 1) (PSK-1) (Kinase from chicken homolog C) (hKFC-C) Length = 1235 Score = 51.2 bits (121), Expect = 2e-06 Identities = 27/82 (32%), Positives = 49/82 (59%), Gaps = 1/82 (1%) Frame = +2 Query: 224 FEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFA-NMDPESVRFMAREIHILRRLDNPN 400 F L +IG G++ +VY ARD+ N ++VA+KK+ ++ E + + +E+ L++L +PN Sbjct: 28 FSDLREIGHGSFGAVYFARDVRNSEVVAIKKMSYSGKQSNEKWQDIIKEVRFLQKLRHPN 87 Query: 401 VIKLEGLVTSRMSSSLYLVFEY 466 I+ G ++ +LV EY Sbjct: 88 TIQYRGCYLREHTA--WLVMEY 107
>TAOK2_MOUSE (Q6ZQ29) Serine/threonine-protein kinase TAO2 (EC 2.7.11.1)| (Thousand and one amino acid protein 2) Length = 1055 Score = 51.2 bits (121), Expect = 2e-06 Identities = 27/82 (32%), Positives = 49/82 (59%), Gaps = 1/82 (1%) Frame = +2 Query: 224 FEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFA-NMDPESVRFMAREIHILRRLDNPN 400 F L +IG G++ +VY ARD+ N ++VA+KK+ ++ E + + +E+ L++L +PN Sbjct: 28 FSDLREIGHGSFGAVYFARDVRNSEVVAIKKMSYSGKQSNEKWQDIIKEVRFLQKLRHPN 87 Query: 401 VIKLEGLVTSRMSSSLYLVFEY 466 I+ G ++ +LV EY Sbjct: 88 TIQYRGCYLREHTA--WLVMEY 107
>TAOK2_XENLA (Q6GPK9) Serine/threonine-protein kinase TAO2 (EC 2.7.11.1)| (Thousand and one amino acid protein 2) Length = 1025 Score = 51.2 bits (121), Expect = 2e-06 Identities = 27/82 (32%), Positives = 50/82 (60%), Gaps = 1/82 (1%) Frame = +2 Query: 224 FEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFA-NMDPESVRFMAREIHILRRLDNPN 400 F L +IG G++ +VY ARD+ N ++VA+KK+ ++ E + + +E+ L++L +PN Sbjct: 28 FADLREIGHGSFGAVYFARDIRNNEVVAIKKMSYSGKQSNEKWQDIIKEVKFLQKLRHPN 87 Query: 401 VIKLEGLVTSRMSSSLYLVFEY 466 I+ +G ++ +LV EY Sbjct: 88 TIEYKGCYLREHTA--WLVMEY 107
>SSK2_YEAST (P53599) MAP kinase kinase kinase SSK2 (EC 2.7.11.25) (Suppressor of| sensor kinase 2) Length = 1579 Score = 50.8 bits (120), Expect = 3e-06 Identities = 34/116 (29%), Positives = 60/116 (51%), Gaps = 4/116 (3%) Frame = +2 Query: 224 FEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVR----FMAREIHILRRLD 391 ++K + IG GT+ VY A DL+NG+I+A+K++ D +S++ + E+ +L L+ Sbjct: 1266 WQKRNFIGGGTFGRVYSAVDLDNGEILAVKEINI--QDSKSMQKIFPLIKEEMSVLEILN 1323 Query: 392 NPNVIKLEGLVTSRMSSSLYLVFEYMEHDLAGLAATPGIKFTEAQVKCYMQQLLSG 559 +PN++ G+ R ++++ EY E G E + Y QLL G Sbjct: 1324 HPNIVSYYGVEVHRDKVNIFM--EYCEGGSLAALLEHGRIEDEMVTQVYTLQLLEG 1377
>STK25_MOUSE (Q9Z2W1) Serine/threonine-protein kinase 25 (EC 2.7.11.1) (Sterile| 20/oxidant stress-response kinase 1) (Ste20/oxidant stress response kinase 1) (SOK-1) (Ste20-like kinase) Length = 426 Score = 50.8 bits (120), Expect = 3e-06 Identities = 32/114 (28%), Positives = 60/114 (52%) Frame = +2 Query: 218 ESFEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRFMAREIHILRRLDNP 397 E F KLD+IG+G++ VYK D ++VA+K + + E + + +EI +L + D+P Sbjct: 18 ELFTKLDRIGKGSFGEVYKGIDNHTKEVVAIKIIDLEEAEDE-IEDIQQEITVLSQCDSP 76 Query: 398 NVIKLEGLVTSRMSSSLYLVFEYMEHDLAGLAATPGIKFTEAQVKCYMQQLLSG 559 + + G + S+ L+++ EY+ A PG E + ++++L G Sbjct: 77 YITRYFG--SYLKSTKLWIIMEYLGGGSALDLLKPG-PLEETYIATILREILKG 127
>STK25_HUMAN (O00506) Serine/threonine-protein kinase 25 (EC 2.7.11.1) (Sterile| 20/oxidant stress-response kinase 1) (Ste20/oxidant stress response kinase 1) (SOK-1) (Ste20-like kinase) Length = 426 Score = 50.8 bits (120), Expect = 3e-06 Identities = 32/114 (28%), Positives = 60/114 (52%) Frame = +2 Query: 218 ESFEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRFMAREIHILRRLDNP 397 E F KLD+IG+G++ VYK D ++VA+K + + E + + +EI +L + D+P Sbjct: 18 ELFTKLDRIGKGSFGEVYKGIDNHTKEVVAIKIIDLEEAEDE-IEDIQQEITVLSQCDSP 76 Query: 398 NVIKLEGLVTSRMSSSLYLVFEYMEHDLAGLAATPGIKFTEAQVKCYMQQLLSG 559 + + G + S+ L+++ EY+ A PG E + ++++L G Sbjct: 77 YITRYFG--SYLKSTKLWIIMEYLGGGSALDLLKPG-PLEETYIATILREILKG 127
>CDPK2_PLAFK (O15865) Calcium-dependent protein kinase 2 (EC 2.7.11.1) (PfCDPK2)| Length = 512 Score = 50.8 bits (120), Expect = 3e-06 Identities = 31/107 (28%), Positives = 55/107 (51%) Frame = +2 Query: 236 DKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRFMAREIHILRRLDNPNVIKLE 415 +K+GQGTY VYK D ++ A+K+ + + +++ +EI I+++LD+PN++KL Sbjct: 75 EKLGQGTYGCVYKGIDKVTNQLYAIKEEKKDRL--KNINRFFQEIEIMKKLDHPNIVKL- 131 Query: 416 GLVTSRMSSSLYLVFEYMEHDLAGLAATPGIKFTEAQVKCYMQQLLS 556 T + +YL+ E + FTE M+Q+ S Sbjct: 132 -YETYENDNYIYLIMELCSGRELFDSIIENGSFTEKNAATIMKQIFS 177
>CDPK2_PLAF7 (Q8ICR0) Calcium-dependent protein kinase 2 (EC 2.7.11.1) (PfCDPK2)| Length = 508 Score = 50.8 bits (120), Expect = 3e-06 Identities = 31/107 (28%), Positives = 55/107 (51%) Frame = +2 Query: 236 DKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRFMAREIHILRRLDNPNVIKLE 415 +K+GQGTY VYK D ++ A+K+ + + +++ +EI I+++LD+PN++KL Sbjct: 75 EKLGQGTYGCVYKGIDKVTNQLYAIKEEKKDRL--KNINRFFQEIEIMKKLDHPNIVKL- 131 Query: 416 GLVTSRMSSSLYLVFEYMEHDLAGLAATPGIKFTEAQVKCYMQQLLS 556 T + +YL+ E + FTE M+Q+ S Sbjct: 132 -YETYENDNYIYLIMELCSGRELFDSIIENGSFTEKNAATIMKQIFS 177
>M3K1_ARATH (O22040) Mitogen-activated protein kinase kinase kinase 1 (EC| 2.7.11.25) (Arabidospsis NPK1-related protein kinase 1) Length = 666 Score = 50.4 bits (119), Expect = 3e-06 Identities = 32/119 (26%), Positives = 64/119 (53%), Gaps = 6/119 (5%) Frame = +2 Query: 221 SFEKLDKIGQGTYSSVYKARDLENGKIVALKKV----RFANMDPES--VRFMAREIHILR 382 S+ K IG+G + +VY +L++G+++A+K+V FA+ + ++ + E+ +L+ Sbjct: 68 SWRKGQLIGRGAFGTVYMGMNLDSGELLAVKQVLIAANFASKEKTQAHIQELEEEVKLLK 127 Query: 383 RLDNPNVIKLEGLVTSRMSSSLYLVFEYMEHDLAGLAATPGIKFTEAQVKCYMQQLLSG 559 L +PN+++ G T R +L ++ E++ F E+ V+ Y +QLL G Sbjct: 128 NLSHPNIVRYLG--TVREDDTLNILLEFVPGGSISSLLEKFGPFPESVVRTYTRQLLLG 184
>IKKE_HUMAN (Q14164) Inhibitor of nuclear factor kappa-B kinase epsilon subunit| (EC 2.7.11.1) (I kappa-B kinase epsilon) (IkBKE) (IKK-epsilon) (IKK-E) (Inducible I kappa-B kinase) (IKK-i) Length = 716 Score = 50.4 bits (119), Expect = 3e-06 Identities = 29/78 (37%), Positives = 48/78 (61%), Gaps = 1/78 (1%) Frame = +2 Query: 236 DKIGQGTYSSVYKARDLENGKIVALKKVRFAN-MDPESVRFMAREIHILRRLDNPNVIKL 412 D +GQG +SVYKAR+ ++G++VA+K + + P V+ RE +LR+L++ N++KL Sbjct: 13 DLLGQGATASVYKARNKKSGELVAVKVFNTTSYLRPREVQ--VREFEVLRKLNHQNIVKL 70 Query: 413 EGLVTSRMSSSLYLVFEY 466 + + S LV EY Sbjct: 71 FAVEETGGSRQKVLVMEY 88
>NEK1_HUMAN (Q96PY6) Serine/threonine-protein kinase Nek1 (EC 2.7.11.1)| (NimA-related protein kinase 1) (NY-REN-55 antigen) Length = 1258 Score = 50.4 bits (119), Expect = 3e-06 Identities = 27/113 (23%), Positives = 56/113 (49%), Gaps = 2/113 (1%) Frame = +2 Query: 218 ESFEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRFMAREIHILRRLDNP 397 E + +L KIG+G++ + E+G+ +K++ + M + RE+ +L + +P Sbjct: 2 EKYVRLQKIGEGSFGKAILVKSTEDGRQYVIKEINISRMSSKEREESRREVAVLANMKHP 61 Query: 398 NVIKLEGLVTSRMSSSLYLVFEYMEHD--LAGLAATPGIKFTEAQVKCYMQQL 550 N+++ + + SLY+V +Y E + A G+ F E Q+ + Q+ Sbjct: 62 NIVQYR--ESFEENGSLYIVMDYCEGGDLFKRINAQKGVLFQEDQILDWFVQI 112
>KSG4_ARATH (Q9FVS6) Shaggy-related protein kinase delta (EC 2.7.11.1)| (ASK-delta) Length = 420 Score = 50.1 bits (118), Expect = 4e-06 Identities = 42/131 (32%), Positives = 67/131 (51%), Gaps = 5/131 (3%) Frame = +2 Query: 92 EAKPRIIDVPNGVVAE--HVAAGWPRWLTEVATEAVRGWQPRKAESFEKLDKIGQGTYSS 265 +++P IID GV AE HV T R Q R+ S+ +G G++ Sbjct: 48 DSEPDIID---GVGAEPGHVIT---------TTLPGRNGQSRQTVSYIAEHVVGTGSFGM 95 Query: 266 VYKARDLENGKIVALKKVRFANMDPESVRFMAREIHILRRLDNPNVIKLEGLVTSRMSSS 445 V++A+ E G++VA+KKV + R+ RE+ I++ LD+PNV+ L+ SR + Sbjct: 96 VFQAKCRETGEVVAIKKVL------QDKRYKNRELQIMQMLDHPNVVCLKHSFYSRTENE 149 Query: 446 ---LYLVFEYM 469 L LV E++ Sbjct: 150 EVYLNLVLEFV 160
>M4K2_MOUSE (Q61161) Mitogen-activated protein kinase kinase kinase kinase 2| (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 2) (MEK kinase kinase 2) (MEKKK 2) (Germinal center kinase) (GCK) (Rab8-interacting protein) Length = 821 Score = 50.1 bits (118), Expect = 4e-06 Identities = 27/68 (39%), Positives = 41/68 (60%), Gaps = 1/68 (1%) Frame = +2 Query: 218 ESFEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDP-ESVRFMAREIHILRRLDN 394 + FE L ++G GTY VYKARD ++ A+K V+ +DP + + + +EI ILR + Sbjct: 14 DRFELLQRVGAGTYGDVYKARDTVTSELAAVKIVK---LDPGDDISSLQQEITILRECRH 70 Query: 395 PNVIKLEG 418 PNV+ G Sbjct: 71 PNVVAYIG 78
>ERK1_DICDI (P42525) Extracellular signal-regulated kinase 1 (EC 2.7.11.24)| (ERK1) (MAP kinase 1) Length = 415 Score = 50.1 bits (118), Expect = 4e-06 Identities = 31/109 (28%), Positives = 57/109 (52%), Gaps = 3/109 (2%) Frame = +2 Query: 242 IGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRFMAREIHILRRLDNPNVIKLEGL 421 IG G Y V A+D G+ VA+KK+ A + + + REIH+LR + N+I ++ + Sbjct: 37 IGHGAYGVVCSAKDNLTGEKVAIKKISKAFDNLKDTKRTLREIHLLRHFKHENLISIKDI 96 Query: 422 V---TSRMSSSLYLVFEYMEHDLAGLAATPGIKFTEAQVKCYMQQLLSG 559 + + +Y+V E M+ DL + +P ++ + ++ Q+L G Sbjct: 97 LKPNSKEQFEDVYIVSELMDTDLHQIITSPQ-PLSDDHCQYFVYQMLRG 144
>M4K2_HUMAN (Q12851) Mitogen-activated protein kinase kinase kinase kinase 2| (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 2) (MEK kinase kinase 2) (MEKKK 2) (Germinal center kinase) (GC kinase) (Rab8-interacting protein) (B lymphocyte serine/threonine-pro Length = 819 Score = 50.1 bits (118), Expect = 4e-06 Identities = 27/68 (39%), Positives = 41/68 (60%), Gaps = 1/68 (1%) Frame = +2 Query: 218 ESFEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDP-ESVRFMAREIHILRRLDN 394 + FE L ++G GTY VYKARD ++ A+K V+ +DP + + + +EI ILR + Sbjct: 13 DRFELLQRVGAGTYGDVYKARDTVTSELAAVKIVK---LDPGDDISSLQQEITILRECRH 69 Query: 395 PNVIKLEG 418 PNV+ G Sbjct: 70 PNVVAYIG 77
>E2AK1_SCHPO (O13889) Eukaryotic translation initiation factor 2-alpha kinase 1| (EC 2.7.11.1) (Heme-regulated eukaryotic initiation factor eIF-2-alpha kinase) (Heme-regulated inhibitor 1) Length = 704 Score = 49.7 bits (117), Expect = 6e-06 Identities = 28/67 (41%), Positives = 40/67 (59%) Frame = +2 Query: 209 RKAESFEKLDKIGQGTYSSVYKARDLENGKIVALKKVRFANMDPESVRFMAREIHILRRL 388 R A FE+L+ +G+G Y SVYKAR+ +G ALKK+ + + RE L RL Sbjct: 219 RYASDFEELELLGKGGYGSVYKARNKFDGVEYALKKIPLRLRSFSTSSNIFRESRTLARL 278 Query: 389 DNPNVIK 409 ++PNVI+ Sbjct: 279 NHPNVIR 285 Database: uniprot_sprot.fasta Posted date: May 25, 2006 5:36 PM Number of letters in database: 80,573,946 Number of sequences in database: 219,361 Lambda K H 0.318 0.135 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 86,126,914 Number of Sequences: 219361 Number of extensions: 1864141 Number of successful extensions: 8694 Number of sequences better than 10.0: 500 Number of HSP's better than 10.0 without gapping: 7273 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 8204 length of database: 80,573,946 effective HSP length: 106 effective length of database: 57,321,680 effective search space used: 4585734400 frameshift window, decay const: 50, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
