ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
menu 
| Clone Name | bah62h20 |
|---|---|
| Clone Library Name | barley_pub |
>IRAK1_MOUSE (Q62406) Interleukin-1 receptor-associated kinase 1 (EC 2.7.11.1)| (IRAK-1) (IRAK) (Pelle-like protein kinase) (mPLK) Length = 710 Score = 61.6 bits (148), Expect = 2e-09 Identities = 35/90 (38%), Positives = 48/90 (53%), Gaps = 7/90 (7%) Frame = +1 Query: 367 PKALPLSLLDEITCGFSEKQEIGRGGFAVVYEGSLLNVTVAVKKLTNLHMRDAPEVEYN- 543 P P + + TC FSE+ IG GGF VY + N T AVK+L ++ ++E+ Sbjct: 197 PFCWPFCEISQGTCNFSEELRIGEGGFGCVYRAVMRNTTYAVKRL-----KEEADLEWTM 251 Query: 544 ------REVECLMRVKHKNIVRFLGYCADT 615 EVE L R +H NIV F GYCA++ Sbjct: 252 VKQSFLTEVEQLSRFRHPNIVDFAGYCAES 281
>TMK1_ARATH (P43298) Putative receptor protein kinase TMK1 precursor (EC| 2.7.11.1) Length = 942 Score = 59.7 bits (143), Expect = 7e-09 Identities = 34/105 (32%), Positives = 58/105 (55%), Gaps = 1/105 (0%) Frame = +1 Query: 301 DIQMIPSTVEDLESMVIDESAEPKALPLSLLDEITCGFSEKQEIGRGGFAVVYEGSLLNV 480 D +P T E +++ + E+ + + +L +T FS +G GGF VVY+G L + Sbjct: 552 DTYTLPGTSEVGDNIQMVEAGN-MLISIQVLRSVTNNFSSDNILGSGGFGVVYKGELHDG 610 Query: 481 T-VAVKKLTNLHMRDAPEVEYNREVECLMRVKHKNIVRFLGYCAD 612 T +AVK++ N + E+ E+ L +V+H+++V LGYC D Sbjct: 611 TKIAVKRMENGVIAGKGFAEFKSEIAVLTKVRHRHLVTLLGYCLD 655
>BRL2_ARATH (Q9ZPS9) Serine/threonine-protein kinase BRI1-like 2 precursor (EC| 2.7.11.1) (BRASSINOSTEROID INSENSITIVE 1-like protein 2) (Protein VASCULAR HIGHWAY 1) Length = 1143 Score = 56.6 bits (135), Expect = 6e-08 Identities = 36/94 (38%), Positives = 52/94 (55%), Gaps = 1/94 (1%) Frame = +1 Query: 328 EDLESMVIDESAEPKALPLSLLDEITCGFSEKQEIGRGGFAVVYEGSLLN-VTVAVKKLT 504 E L V + + L S L E T GFS IG GGF V++ +L + +VA+KKL Sbjct: 810 EPLSINVATFQRQLRKLKFSQLIEATNGFSAASMIGHGGFGEVFKATLKDGSSVAIKKLI 869 Query: 505 NLHMRDAPEVEYNREVECLMRVKHKNIVRFLGYC 606 L + + E+ E+E L ++KH+N+V LGYC Sbjct: 870 RLSCQG--DREFMAEMETLGKIKHRNLVPLLGYC 901
>IRAK1_HUMAN (P51617) Interleukin-1 receptor-associated kinase 1 (EC 2.7.11.1)| (IRAK-1) Length = 712 Score = 56.2 bits (134), Expect = 7e-08 Identities = 35/83 (42%), Positives = 44/83 (53%), Gaps = 2/83 (2%) Frame = +1 Query: 367 PKALPLSLLDEITCGFSEKQEIGRGGFAVVYEGSLLNVTVAVKKL-TNLHMR-DAPEVEY 540 P PL + T FSE+ +IG GGF VY + N AVK+L N + A + + Sbjct: 197 PFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSF 256 Query: 541 NREVECLMRVKHKNIVRFLGYCA 609 EVE L R +H NIV F GYCA Sbjct: 257 LTEVEQLSRFRHPNIVDFAGYCA 279
>CRI4_MAIZE (O24585) Putative receptor protein kinase CRINKLY4 precursor (EC| 2.7.11.1) Length = 901 Score = 55.1 bits (131), Expect = 2e-07 Identities = 31/95 (32%), Positives = 52/95 (54%), Gaps = 1/95 (1%) Frame = +1 Query: 331 DLESMVIDESAEPKALPLSLLDEITCGFSEKQEIGRGGFAVVYEGSLLNVT-VAVKKLTN 507 D+E + I + E L++ T GFSE ++G+G F+ V++G L + T VAVK+ Sbjct: 481 DMEDLKIRRAQE---FSYEELEQATGGFSEDSQVGKGSFSCVFKGILRDGTVVAVKRAIK 537 Query: 508 LHMRDAPEVEYNREVECLMRVKHKNIVRFLGYCAD 612 E++ E++ L R+ H +++ LGYC D Sbjct: 538 ASDVKKSSKEFHNELDLLSRLNHAHLLNLLGYCED 572
>BRI1_LYCPE (Q8L899) Systemin receptor SR160 precursor (EC 2.7.11.1)| (Brassinosteroid LRR receptor kinase) Length = 1207 Score = 53.5 bits (127), Expect = 5e-07 Identities = 30/80 (37%), Positives = 47/80 (58%), Gaps = 1/80 (1%) Frame = +1 Query: 370 KALPLSLLDEITCGFSEKQEIGRGGFAVVYEGSLLNVTV-AVKKLTNLHMRDAPEVEYNR 546 + L + L E T GF +G GGF VY+ L + +V A+KKL +H+ + E+ Sbjct: 874 RKLTFADLLEATNGFHNDSLVGSGGFGDVYKAQLKDGSVVAIKKL--IHVSGQGDREFTA 931 Query: 547 EVECLMRVKHKNIVRFLGYC 606 E+E + ++KH+N+V LGYC Sbjct: 932 EMETIGKIKHRNLVPLLGYC 951
>BRI1_LYCES (Q8GUQ5) Brassinosteroid LRR receptor kinase precursor (EC 2.7.11.1)| (tBRI1) (Altered brassinolide sensitivity 1) (Systemin receptor SR160) Length = 1207 Score = 53.5 bits (127), Expect = 5e-07 Identities = 30/80 (37%), Positives = 47/80 (58%), Gaps = 1/80 (1%) Frame = +1 Query: 370 KALPLSLLDEITCGFSEKQEIGRGGFAVVYEGSLLNVTV-AVKKLTNLHMRDAPEVEYNR 546 + L + L E T GF +G GGF VY+ L + +V A+KKL +H+ + E+ Sbjct: 874 RKLTFADLLEATNGFHNDSLVGSGGFGDVYKAQLKDGSVVAIKKL--IHVSGQGDREFTA 931 Query: 547 EVECLMRVKHKNIVRFLGYC 606 E+E + ++KH+N+V LGYC Sbjct: 932 EMETIGKIKHRNLVPLLGYC 951
>BRL1_ARATH (Q9ZWC8) Serine/threonine-protein kinase BRI1-like 1 precursor (EC| 2.7.11.1) (BRASSINOSTEROID INSENSITIVE 1-like protein 1) Length = 1166 Score = 53.1 bits (126), Expect = 6e-07 Identities = 34/99 (34%), Positives = 53/99 (53%), Gaps = 1/99 (1%) Frame = +1 Query: 313 IPSTVEDLESMVIDESAEPKALPLSLLDEITCGFSEKQEIGRGGFAVVYEGSLLNVTV-A 489 + S E L V + L + L E T GFS + +G GGF VY+ L + +V A Sbjct: 826 LSSVPEPLSINVATFEKPLRKLTFAHLLEATNGFSAETMVGSGGFGEVYKAQLRDGSVVA 885 Query: 490 VKKLTNLHMRDAPEVEYNREVECLMRVKHKNIVRFLGYC 606 +KKL + + + E+ E+E + ++KH+N+V LGYC Sbjct: 886 IKKL--IRITGQGDREFMAEMETIGKIKHRNLVPLLGYC 922
>EXS_ARATH (Q9LYN8) Leucine-rich repeat receptor protein kinase EXS precursor| (EC 2.7.11.1) (Extra sporogenous cells protein) (EXCESS MICROSPOROCYTES1 protein) Length = 1192 Score = 53.1 bits (126), Expect = 6e-07 Identities = 33/72 (45%), Positives = 42/72 (58%), Gaps = 1/72 (1%) Frame = +1 Query: 397 EITCGFSEKQEIGRGGFAVVYEGSLLNV-TVAVKKLTNLHMRDAPEVEYNREVECLMRVK 573 E T FS+K IG GGF VY+ L TVAVKKL+ + E+ E+E L +VK Sbjct: 912 EATDHFSKKNIIGDGGFGTVYKACLPGEKTVAVKKLSEAKTQG--NREFMAEMETLGKVK 969 Query: 574 HKNIVRFLGYCA 609 H N+V LGYC+ Sbjct: 970 HPNLVSLLGYCS 981
>BRL3_ARATH (Q9LJF3) Serine/threonine-protein kinase BRI1-like 3 precursor (EC| 2.7.11.1) (BRASSINOSTEROID INSENSITIVE 1-like protein 3) Length = 1164 Score = 52.8 bits (125), Expect = 8e-07 Identities = 31/80 (38%), Positives = 47/80 (58%), Gaps = 1/80 (1%) Frame = +1 Query: 370 KALPLSLLDEITCGFSEKQEIGRGGFAVVYEGSLLNVTV-AVKKLTNLHMRDAPEVEYNR 546 + L + L E T GFS IG GGF VY+ L + +V A+KKL + + + E+ Sbjct: 844 RKLTFAHLLEATNGFSADSMIGSGGFGDVYKAKLADGSVVAIKKL--IQVTGQGDREFMA 901 Query: 547 EVECLMRVKHKNIVRFLGYC 606 E+E + ++KH+N+V LGYC Sbjct: 902 EMETIGKIKHRNLVPLLGYC 921
>IRAK4_HUMAN (Q9NWZ3) Interleukin-1 receptor-associated kinase 4 (EC 2.7.11.1)| (IRAK-4) (NY-REN-64 antigen) Length = 460 Score = 52.8 bits (125), Expect = 8e-07 Identities = 28/82 (34%), Positives = 49/82 (59%), Gaps = 8/82 (9%) Frame = +1 Query: 391 LDEITCGFSEK------QEIGRGGFAVVYEGSLLNVTVAVKKLTNLHMRDAPEV--EYNR 546 L +T F E+ ++G GGF VVY+G + N TVAVKKL + E+ ++++ Sbjct: 173 LKNVTNNFDERPISVGGNKMGEGGFGVVYKGYVNNTTVAVKKLAAMVDITTEELKQQFDQ 232 Query: 547 EVECLMRVKHKNIVRFLGYCAD 612 E++ + + +H+N+V LG+ +D Sbjct: 233 EIKVMAKCQHENLVELLGFSSD 254
>BAK1_ARATH (Q94F62) BRASSINOSTEROID INSENSITIVE 1-associated receptor kinase 1| precursor (EC 2.7.11.1) (BRI1-associated receptor kinase 1) (Somatic embryogenesis receptor-like kinase 3) Length = 615 Score = 51.2 bits (121), Expect = 2e-06 Identities = 26/79 (32%), Positives = 39/79 (49%) Frame = +1 Query: 370 KALPLSLLDEITCGFSEKQEIGRGGFAVVYEGSLLNVTVAVKKLTNLHMRDAPEVEYNRE 549 K L L + FS K +GRGGF VY+G L + T+ K E+++ E Sbjct: 275 KRFSLRELQVASDNFSNKNILGRGGFGKVYKGRLADGTLVAVKRLKEERTQGGELQFQTE 334 Query: 550 VECLMRVKHKNIVRFLGYC 606 VE + H+N++R G+C Sbjct: 335 VEMISMAVHRNLLRLRGFC 353
>YR831_MIMIV (Q7T6Y2) Putative serine/threonine-protein kinase/receptor R831| precursor (EC 2.7.11.1) Length = 1624 Score = 51.2 bits (121), Expect = 2e-06 Identities = 26/71 (36%), Positives = 39/71 (54%) Frame = +1 Query: 394 DEITCGFSEKQEIGRGGFAVVYEGSLLNVTVAVKKLTNLHMRDAPEVEYNREVECLMRVK 573 DEI+ G ++IG G + +V+ G V VAVKK + + +E+ E+ L +K Sbjct: 1362 DEISIG----KQIGLGSYGIVFNGKWKGVDVAVKKFVKQKLSETQLLEFRAEMAFLSELK 1417 Query: 574 HKNIVRFLGYC 606 H NIV F+G C Sbjct: 1418 HSNIVTFIGAC 1428 Score = 37.7 bits (86), Expect = 0.027 Identities = 17/58 (29%), Positives = 32/58 (55%) Frame = +1 Query: 424 QEIGRGGFAVVYEGSLLNVTVAVKKLTNLHMRDAPEVEYNREVECLMRVKHKNIVRFL 597 + +G GG+ VY+ VAVK +++ H+ E + EV+ + ++H N+V F+ Sbjct: 790 ETLGTGGYGEVYKSIWKGTEVAVKLISSKHVSKDMERSFFEEVKIMTSLRHPNVVLFM 847
>SRK6_BRAOE (Q09092) Putative serine/threonine-protein kinase receptor| precursor (EC 2.7.11.1) (S-receptor kinase) (SRK) Length = 849 Score = 51.2 bits (121), Expect = 2e-06 Identities = 30/103 (29%), Positives = 56/103 (54%), Gaps = 1/103 (0%) Frame = +1 Query: 307 QMIPSTVEDLESMVIDESAEPKALPLSLLDEITCGFSEKQEIGRGGFAVVYEGSLLN-VT 483 +M+ S+ + E E + + + + T FS ++G+GGF +VY+G LL+ Sbjct: 493 EMVLSSKREFSGEYKFEELELPLIEMETVVKATENFSSCNKLGQGGFGIVYKGRLLDGKE 552 Query: 484 VAVKKLTNLHMRDAPEVEYNREVECLMRVKHKNIVRFLGYCAD 612 +AVK+L+ ++ E+ EV + R++H N+V+ LG C + Sbjct: 553 IAVKRLSKTSVQGTD--EFMNEVTLIARLQHINLVQVLGCCIE 593
>BRI1_ARATH (O22476) BRASSINOSTEROID INSENSITIVE 1 precursor (EC 2.7.11.1)| (AtBRI1) (Brassinosteroid LRR receptor kinase) Length = 1196 Score = 51.2 bits (121), Expect = 2e-06 Identities = 30/80 (37%), Positives = 47/80 (58%), Gaps = 1/80 (1%) Frame = +1 Query: 370 KALPLSLLDEITCGFSEKQEIGRGGFAVVYEGSLLNVT-VAVKKLTNLHMRDAPEVEYNR 546 + L + L + T GF IG GGF VY+ L + + VA+KKL +H+ + E+ Sbjct: 869 RKLTFADLLQATNGFHNDSLIGSGGFGDVYKAILKDGSAVAIKKL--IHVSGQGDREFMA 926 Query: 547 EVECLMRVKHKNIVRFLGYC 606 E+E + ++KH+N+V LGYC Sbjct: 927 EMETIGKIKHRNLVPLLGYC 946
>PSKR_DAUCA (Q8LPB4) Phytosulfokine receptor precursor (EC 2.7.11.1)| (Phytosulfokine LRR receptor kinase) Length = 1021 Score = 50.1 bits (118), Expect = 5e-06 Identities = 32/78 (41%), Positives = 47/78 (60%), Gaps = 6/78 (7%) Frame = +1 Query: 391 LDEI---TCGFSEKQEIGRGGFAVVYEGSLLNVT-VAVKKLTNLHMRDAPEV--EYNREV 552 LD+I T F++ IG GGF +VY+ +L + T VA+K+L+ D ++ E+ EV Sbjct: 733 LDDILKSTSSFNQANIIGCGGFGLVYKATLPDGTKVAIKRLSG----DTGQMDREFQAEV 788 Query: 553 ECLMRVKHKNIVRFLGYC 606 E L R +H N+V LGYC Sbjct: 789 ETLSRAQHPNLVHLLGYC 806
>IRAK4_MOUSE (Q8R4K2) Interleukin-1 receptor-associated kinase 4 (EC 2.7.11.1)| (IRAK-4) Length = 459 Score = 49.7 bits (117), Expect = 7e-06 Identities = 28/83 (33%), Positives = 47/83 (56%), Gaps = 8/83 (9%) Frame = +1 Query: 391 LDEITCGFSEK------QEIGRGGFAVVYEGSLLNVTVAVKKLTNLHMRDAPEV--EYNR 546 L IT F E+ +G GGF VVY+G + N VAVKKL + E+ ++++ Sbjct: 173 LKSITNNFDEQPASAGGNRMGEGGFGVVYKGCVNNTIVAVKKLGAMVEISTEELKQQFDQ 232 Query: 547 EVECLMRVKHKNIVRFLGYCADT 615 E++ + +H+N+V LG+ +D+ Sbjct: 233 EIKVMATCQHENLVELLGFSSDS 255
>CLV1_ARATH (Q9SYQ8) Receptor protein kinase CLAVATA1 precursor (EC 2.7.11.1)| Length = 980 Score = 48.5 bits (114), Expect = 2e-05 Identities = 28/74 (37%), Positives = 44/74 (59%), Gaps = 1/74 (1%) Frame = +1 Query: 394 DEITCGFSEKQEIGRGGFAVVYEGSLLN-VTVAVKKLTNLHMRDAPEVEYNREVECLMRV 570 D + C E+ IG+GG +VY GS+ N V VA+K+L + + E++ L R+ Sbjct: 687 DVLEC-LKEENIIGKGGAGIVYRGSMPNNVDVAIKRLVG-RGTGRSDHGFTAEIQTLGRI 744 Query: 571 KHKNIVRFLGYCAD 612 +H++IVR LGY A+ Sbjct: 745 RHRHIVRLLGYVAN 758
>SIRK_ARATH (O64483) Senescence-induced receptor-like serine/threonine-protein| kinase precursor (FLG22-induced receptor-like kinase 1) Length = 876 Score = 46.6 bits (109), Expect = 6e-05 Identities = 25/59 (42%), Positives = 33/59 (55%) Frame = +1 Query: 430 IGRGGFAVVYEGSLLNVTVAVKKLTNLHMRDAPEVEYNREVECLMRVKHKNIVRFLGYC 606 IG+GGF VY G + VAVK L+ + E + EV+ LMRV H N+ +GYC Sbjct: 580 IGKGGFGKVYHGVINGEQVAVKVLSEESAQGYKE--FRAEVDLLMRVHHTNLTSLVGYC 636
>KYK2_DICDI (P18161) Tyrosine-protein kinase 2 (EC 2.7.10.2) (Fragment)| Length = 410 Score = 46.6 bits (109), Expect = 6e-05 Identities = 23/61 (37%), Positives = 37/61 (60%) Frame = +1 Query: 424 QEIGRGGFAVVYEGSLLNVTVAVKKLTNLHMRDAPEVEYNREVECLMRVKHKNIVRFLGY 603 Q++G G F+ V+EG + VA+KKL + + + + REV+ L + H+NIV F+G Sbjct: 112 QKVGEGAFSEVWEGWWKGIHVAIKKLKIIGDEEQFKERFIREVQNLKKGNHQNIVMFIGA 171 Query: 604 C 606 C Sbjct: 172 C 172
>PSKR_ARATH (Q9ZVR7) Putative phytosulfokine receptor precursor (EC 2.7.11.1)| (Phytosulfokine LRR receptor kinase) Length = 1008 Score = 45.1 bits (105), Expect = 2e-04 Identities = 31/91 (34%), Positives = 48/91 (52%), Gaps = 3/91 (3%) Frame = +1 Query: 343 MVIDESAEPKALPLSLLDEITCGFSEKQEIGRGGFAVVYEGSLLN-VTVAVKKLTNLHMR 519 +V+ + K L L + T F + IG GGF +VY+ +L + VA+KKL+ Sbjct: 711 LVVLFQSNDKELSYDDLLDSTNSFDQANIIGCGGFGMVYKATLPDGKKVAIKKLSG---- 766 Query: 520 DAPEVE--YNREVECLMRVKHKNIVRFLGYC 606 D ++E + EVE L R +H N+V G+C Sbjct: 767 DCGQIEREFEAEVETLSRAQHPNLVLLRGFC 797
>KPRO_MAIZE (P17801) Putative receptor protein kinase ZmPK1 precursor (EC| 2.7.11.1) Length = 817 Score = 43.9 bits (102), Expect = 4e-04 Identities = 27/65 (41%), Positives = 39/65 (60%), Gaps = 1/65 (1%) Frame = +1 Query: 421 KQEIGRGGFAVVYEGSLLNVT-VAVKKLTNLHMRDAPEVEYNREVECLMRVKHKNIVRFL 597 K E+GRG VY+G L + VAVKKL N+ R EV + E+ + R+ H N+VR Sbjct: 537 KVELGRGESGTVYKGVLEDDRHVAVKKLENV--RQGKEV-FQAELSVIGRINHMNLVRIW 593 Query: 598 GYCAD 612 G+C++ Sbjct: 594 GFCSE 598
>ROR1_DROME (Q24488) Tyrosine-protein kinase transmembrane receptor Ror| precursor (EC 2.7.10.1) (dRor) Length = 685 Score = 43.1 bits (100), Expect = 6e-04 Identities = 24/64 (37%), Positives = 37/64 (57%), Gaps = 5/64 (7%) Frame = +1 Query: 424 QEIGRGGFAVVYEGSLLN-----VTVAVKKLTNLHMRDAPEVEYNREVECLMRVKHKNIV 588 +E+G G F VY+G LL +TVA+K L + + ++ RE+E + +KH+NIV Sbjct: 414 EELGEGAFGKVYKGQLLQPNKTTITVAIKALKE-NASVKTQQDFKREIELISDLKHQNIV 472 Query: 589 RFLG 600 LG Sbjct: 473 CILG 476
>TNI3K_MOUSE (Q5GIG6) Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1)| (TNNI3-interacting kinase) (Cardiac ankyrin repeat kinase) Length = 833 Score = 42.7 bits (99), Expect = 8e-04 Identities = 32/104 (30%), Positives = 49/104 (47%), Gaps = 4/104 (3%) Frame = +1 Query: 313 IPSTVEDLESMVIDESAEPKALPLSLLDEITCGFSE---KQEIGRGGFAVVYEGSLLNVT 483 +PS + ++SM E A+ L L SE + IG G F VY+G N Sbjct: 426 VPSPLGKIKSMT-KEKADVLLLRAELPSRFHLQLSEIEFHEIIGSGSFGKVYKGRCRNKI 484 Query: 484 VAVKKL-TNLHMRDAPEVEYNREVECLMRVKHKNIVRFLGYCAD 612 VA+K+ N + + + REV L ++ H +V+F+G C D Sbjct: 485 VAIKRYRANTYCSKSDVDMFCREVSILCQLNHPCVVQFVGACLD 528
>PBS1_ARATH (Q9FE20) Serine/threonine-protein kinase PBS1 (EC 2.7.11.1)| (AvrPphB susceptible protein 1) Length = 456 Score = 42.7 bits (99), Expect = 8e-04 Identities = 42/123 (34%), Positives = 54/123 (43%), Gaps = 19/123 (15%) Frame = +1 Query: 301 DIQMIPSTVEDLESMVIDESAEPKALPLSLLDEI-------------TCGFSEKQEIGRG 441 +I +PS E L S S LP L +I T F +G G Sbjct: 36 NISGLPSGGEKLSSKTNGGSKRELLLPRDGLGQIAAHTFAFRELAAATMNFHPDTFLGEG 95 Query: 442 GFAVVYEGSLLNV--TVAVKKLTNLHMRDAPEVEYNRE--VECLMR--VKHKNIVRFLGY 603 GF VY+G L + VAVK+L D ++ NRE VE LM + H N+V +GY Sbjct: 96 GFGRVYKGRLDSTGQVVAVKQL------DRNGLQGNREFLVEVLMLSLLHHPNLVNLIGY 149 Query: 604 CAD 612 CAD Sbjct: 150 CAD 152
>TNI3K_RAT (Q7TQP6) Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1)| (TNNI3-interacting kinase) (Cardiac ankyrin repeat kinase) Length = 834 Score = 42.7 bits (99), Expect = 8e-04 Identities = 32/104 (30%), Positives = 49/104 (47%), Gaps = 4/104 (3%) Frame = +1 Query: 313 IPSTVEDLESMVIDESAEPKALPLSLLDEITCGFSE---KQEIGRGGFAVVYEGSLLNVT 483 +PS + ++SM E A+ L L SE + IG G F VY+G N Sbjct: 427 VPSPLGKIKSMT-KEKADVLLLRAELPSRFHLQLSEIEFHEIIGSGSFGKVYKGRCRNKI 485 Query: 484 VAVKKL-TNLHMRDAPEVEYNREVECLMRVKHKNIVRFLGYCAD 612 VA+K+ N + + + REV L ++ H +V+F+G C D Sbjct: 486 VAIKRYRANTYCSKSDVDMFCREVSILCQLNHPCVVQFVGACLD 529
>BUR1_KLULA (Q6CRA9) Serine/threonine-protein kinase BUR1 (EC 2.7.11.22) (EC| 2.7.11.23) Length = 645 Score = 42.4 bits (98), Expect = 0.001 Identities = 28/104 (26%), Positives = 54/104 (51%), Gaps = 6/104 (5%) Frame = +1 Query: 304 IQMIPSTVED----LESMVIDESAEPKALPLSLLDEITCGFSEKQEIGRGGFAVVYEGSL 471 ++ IP+ V+D LE + + K ++ + + E++++G+G F V++G Sbjct: 18 VKQIPTVVKDDKTGLEYIQVQSRENEKVYGVT---KFLNNYREEEKLGQGTFGEVFKGIH 74 Query: 472 L--NVTVAVKKLTNLHMRDAPEVEYNREVECLMRVKHKNIVRFL 597 L N VA+K++ +D + RE+ L R+ HKNIV+ + Sbjct: 75 LGTNRKVAIKRILVRAEKDLFPITAQREITILKRMNHKNIVKLI 118
>WNK4_HUMAN (Q96J92) Serine/threonine-protein kinase WNK4 (EC 2.7.11.1)| (Protein kinase with no lysine 4) (Protein kinase, lysine-deficient 4) Length = 1243 Score = 42.0 bits (97), Expect = 0.001 Identities = 29/91 (31%), Positives = 42/91 (46%), Gaps = 2/91 (2%) Frame = +1 Query: 328 EDLESMVIDESAEPKALPLSLLDEITCGFSEKQEIGRGGFAVVYEGSLLNVTVAVK--KL 501 ED+E+ + S + + L + EIGRG F VY G + TV V +L Sbjct: 158 EDMETQAVATSPDGRYLKFDI------------EIGRGSFKTVYRGLDTDTTVEVAWCEL 205 Query: 502 TNLHMRDAPEVEYNREVECLMRVKHKNIVRF 594 + A ++ EVE L ++H NIVRF Sbjct: 206 QTRKLSRAERQRFSEEVEMLKGLQHPNIVRF 236
>ZYG1_CAEBR (Q621J7) Probable serine/threonine-protein kinase zyg-1 (EC| 2.7.11.1) (Zygote defective protein 1) Length = 709 Score = 42.0 bits (97), Expect = 0.001 Identities = 23/62 (37%), Positives = 35/62 (56%), Gaps = 1/62 (1%) Frame = +1 Query: 412 FSEKQEIGRGGFAVVYEGSLLN-VTVAVKKLTNLHMRDAPEVEYNREVECLMRVKHKNIV 588 F Q+IG+GGF VVY N VA+KK+ N A + E++ + ++H+NIV Sbjct: 13 FQNLQQIGQGGFGVVYSAQRENGEKVAIKKIGNA----ASQTRIKEEIKTMKLLRHRNIV 68 Query: 589 RF 594 +F Sbjct: 69 QF 70
>CTR1_ARATH (Q05609) Serine/threonine-protein kinase CTR1 (EC 2.7.11.1)| Length = 821 Score = 42.0 bits (97), Expect = 0.001 Identities = 28/99 (28%), Positives = 42/99 (42%) Frame = +1 Query: 304 IQMIPSTVEDLESMVIDESAEPKALPLSLLDEITCGFSEKQEIGRGGFAVVYEGSLLNVT 483 I+ P + V + + L +D C + K++IG G F V+ Sbjct: 515 IEAAPMNAPPISQPVPNRANRELGLDGDDMDIPWCDLNIKEKIGAGSFGTVHRAEWHGSD 574 Query: 484 VAVKKLTNLHMRDAPEVEYNREVECLMRVKHKNIVRFLG 600 VAVK L E+ REV + R++H NIV F+G Sbjct: 575 VAVKILMEQDFHAERVNEFLREVAIMKRLRHPNIVLFMG 613
>NORK_MEDTR (Q8L4H4) Nodulation receptor kinase precursor (EC 2.7.11.1) (Does| not make infections protein 2) (Symbiosis receptor-like kinase) (MtSYMRK) Length = 925 Score = 41.6 bits (96), Expect = 0.002 Identities = 28/85 (32%), Positives = 45/85 (52%), Gaps = 1/85 (1%) Frame = +1 Query: 355 ESAEPKALPLSLLDEITCGFSEKQEIGRGGFAVVYEGSLLN-VTVAVKKLTNLHMRDAPE 531 +S K L +++ T + K IG GGF VY G+L + VAVK ++ + E Sbjct: 579 KSVSVKPFTLEYIEQATEQY--KTLIGEGGFGSVYRGTLDDGQEVAVKVRSSTSTQGTRE 636 Query: 532 VEYNREVECLMRVKHKNIVRFLGYC 606 ++ E+ L ++H+N+V LGYC Sbjct: 637 --FDNELNLLSAIQHENLVPLLGYC 659
>CX32_ARATH (P27450) Probable serine/threonine-protein kinase Cx32, chloroplast| precursor (EC 2.7.11.1) Length = 419 Score = 41.2 bits (95), Expect = 0.002 Identities = 32/115 (27%), Positives = 52/115 (45%), Gaps = 17/115 (14%) Frame = +1 Query: 319 STVEDLESMVIDESAE----PKALPLSLLD--EITCGFSEKQEIGRGGFAVVYEGSLLNV 480 S D+ + +I +S + P + LD T F +G+GGF VY G + Sbjct: 49 SQFSDISTGIISDSGKLLESPNLKVYNFLDLKTATKNFKPDSMLGQGGFGKVYRGWVDAT 108 Query: 481 T-----------VAVKKLTNLHMRDAPEVEYNREVECLMRVKHKNIVRFLGYCAD 612 T VA+K+L + ++ E+ EV L + H+N+V+ LGYC + Sbjct: 109 TLAPSRVGSGMIVAIKRLNSESVQGF--AEWRSEVNFLGMLSHRNLVKLLGYCRE 161
>NTRK3_SAIBB (Q5IS82) NT-3 growth factor receptor precursor (EC 2.7.10.1)| (Neurotrophic tyrosine kinase receptor type 3) Length = 825 Score = 41.2 bits (95), Expect = 0.002 Identities = 24/71 (33%), Positives = 38/71 (53%), Gaps = 7/71 (9%) Frame = +1 Query: 421 KQEIGRGGFAVVYEGSLLNVT-------VAVKKLTNLHMRDAPEVEYNREVECLMRVKHK 579 K+E+G G F V+ N++ VAVK L + + A ++ RE E L ++H+ Sbjct: 541 KRELGEGAFGKVFLAECYNLSPTKDKMLVAVKALKDPTL--AARKDFQREAELLTNLQHE 598 Query: 580 NIVRFLGYCAD 612 +IV+F G C D Sbjct: 599 HIVKFYGVCGD 609
>NTRK3_PIG (P24786) NT-3 growth factor receptor precursor (EC 2.7.10.1)| (Neurotrophic tyrosine kinase receptor type 3) (TrkC tyrosine kinase) (GP145-TrkC) (Trk-C) Length = 825 Score = 41.2 bits (95), Expect = 0.002 Identities = 24/71 (33%), Positives = 38/71 (53%), Gaps = 7/71 (9%) Frame = +1 Query: 421 KQEIGRGGFAVVYEGSLLNVT-------VAVKKLTNLHMRDAPEVEYNREVECLMRVKHK 579 K+E+G G F V+ N++ VAVK L + + A ++ RE E L ++H+ Sbjct: 541 KRELGEGAFGKVFLAECYNLSPTKVKMLVAVKALKDPTL--AARKDFQREAELLTNLQHE 598 Query: 580 NIVRFLGYCAD 612 +IV+F G C D Sbjct: 599 HIVKFYGVCGD 609
>NTRK3_PANTR (Q5IS37) NT-3 growth factor receptor precursor (EC 2.7.10.1)| (Neurotrophic tyrosine kinase receptor type 3) Length = 825 Score = 41.2 bits (95), Expect = 0.002 Identities = 24/71 (33%), Positives = 38/71 (53%), Gaps = 7/71 (9%) Frame = +1 Query: 421 KQEIGRGGFAVVYEGSLLNVT-------VAVKKLTNLHMRDAPEVEYNREVECLMRVKHK 579 K+E+G G F V+ N++ VAVK L + + A ++ RE E L ++H+ Sbjct: 541 KRELGEGAFGKVFLAECYNLSPTKDKMLVAVKALKDPTL--AARKDFQREAELLTNLQHE 598 Query: 580 NIVRFLGYCAD 612 +IV+F G C D Sbjct: 599 HIVKFYGVCGD 609
>NTRK3_MACFA (Q5IFJ9) NT-3 growth factor receptor precursor (EC 2.7.10.1)| (Neurotrophic tyrosine kinase receptor type 3) Length = 825 Score = 41.2 bits (95), Expect = 0.002 Identities = 24/71 (33%), Positives = 38/71 (53%), Gaps = 7/71 (9%) Frame = +1 Query: 421 KQEIGRGGFAVVYEGSLLNVT-------VAVKKLTNLHMRDAPEVEYNREVECLMRVKHK 579 K+E+G G F V+ N++ VAVK L + + A ++ RE E L ++H+ Sbjct: 541 KRELGEGAFGKVFLAECYNLSPTKDKMLVAVKALKDPTL--AARKDFQREAELLTNLQHE 598 Query: 580 NIVRFLGYCAD 612 +IV+F G C D Sbjct: 599 HIVKFYGVCGD 609
>NTRK3_HUMAN (Q16288) NT-3 growth factor receptor precursor (EC 2.7.10.1)| (Neurotrophic tyrosine kinase receptor type 3) (TrkC tyrosine kinase) (GP145-TrkC) (Trk-C) Length = 839 Score = 41.2 bits (95), Expect = 0.002 Identities = 24/71 (33%), Positives = 38/71 (53%), Gaps = 7/71 (9%) Frame = +1 Query: 421 KQEIGRGGFAVVYEGSLLNVT-------VAVKKLTNLHMRDAPEVEYNREVECLMRVKHK 579 K+E+G G F V+ N++ VAVK L + + A ++ RE E L ++H+ Sbjct: 541 KRELGEGAFGKVFLAECYNLSPTKDKMLVAVKALKDPTL--AARKDFQREAELLTNLQHE 598 Query: 580 NIVRFLGYCAD 612 +IV+F G C D Sbjct: 599 HIVKFYGVCGD 609
>NTRK3_RAT (Q03351) NT-3 growth factor receptor precursor (EC 2.7.10.1)| (Neurotrophic tyrosine kinase receptor type 3) (TrkC tyrosine kinase) (GP145-TrkC) (Trk-C) Length = 864 Score = 41.2 bits (95), Expect = 0.002 Identities = 24/71 (33%), Positives = 38/71 (53%), Gaps = 7/71 (9%) Frame = +1 Query: 421 KQEIGRGGFAVVYEGSLLNVT-------VAVKKLTNLHMRDAPEVEYNREVECLMRVKHK 579 K+E+G G F V+ N++ VAVK L + + A ++ RE E L ++H+ Sbjct: 541 KRELGEGAFGKVFLAECYNLSPTKDKMLVAVKALKDPTL--AARKDFQREAELLTNLQHE 598 Query: 580 NIVRFLGYCAD 612 +IV+F G C D Sbjct: 599 HIVKFYGVCGD 609
>NTRK3_CHICK (Q91044) NT-3 growth factor receptor precursor (EC 2.7.10.1)| (Neurotrophic tyrosine kinase receptor type 3) (TrkC tyrosine kinase) (Trk-C) Length = 827 Score = 41.2 bits (95), Expect = 0.002 Identities = 24/71 (33%), Positives = 38/71 (53%), Gaps = 7/71 (9%) Frame = +1 Query: 421 KQEIGRGGFAVVYEGSLLNVT-------VAVKKLTNLHMRDAPEVEYNREVECLMRVKHK 579 K+E+G G F V+ N++ VAVK L + + A ++ RE E L ++H+ Sbjct: 543 KRELGEGAFGKVFLAECYNLSPTNDKMLVAVKALKDPTL--AARKDFQREAELLTNLQHE 600 Query: 580 NIVRFLGYCAD 612 +IV+F G C D Sbjct: 601 HIVKFYGVCGD 611
>WNK4_RAT (Q7TPK6) Serine/threonine-protein kinase WNK4 (EC 2.7.11.1)| (Protein kinase with no lysine 4) (Protein kinase, lysine-deficient 4) Length = 1222 Score = 40.8 bits (94), Expect = 0.003 Identities = 29/91 (31%), Positives = 41/91 (45%), Gaps = 2/91 (2%) Frame = +1 Query: 328 EDLESMVIDESAEPKALPLSLLDEITCGFSEKQEIGRGGFAVVYEGSLLNVTVAVK--KL 501 ED E+ + S + + L + EIGRG F VY G + TV V +L Sbjct: 155 EDTETQAVATSPDGRYLKFDI------------EIGRGSFKTVYRGLDTDTTVEVAWCEL 202 Query: 502 TNLHMRDAPEVEYNREVECLMRVKHKNIVRF 594 + A ++ EVE L ++H NIVRF Sbjct: 203 QTRKLSRAERQRFSEEVEMLKGLQHPNIVRF 233
>WNK4_MOUSE (Q80UE6) Serine/threonine-protein kinase WNK4 (EC 2.7.11.1)| (Protein kinase with no lysine 4) (Protein kinase, lysine-deficient 4) Length = 1222 Score = 40.8 bits (94), Expect = 0.003 Identities = 29/91 (31%), Positives = 41/91 (45%), Gaps = 2/91 (2%) Frame = +1 Query: 328 EDLESMVIDESAEPKALPLSLLDEITCGFSEKQEIGRGGFAVVYEGSLLNVTVAVK--KL 501 ED E+ + S + + L + EIGRG F VY G + TV V +L Sbjct: 155 EDTETQAVATSPDGRYLKFDI------------EIGRGSFKTVYRGLDTDTTVEVAWCEL 202 Query: 502 TNLHMRDAPEVEYNREVECLMRVKHKNIVRF 594 + A ++ EVE L ++H NIVRF Sbjct: 203 QTRKLSRAERQRFSEEVEMLKGLQHPNIVRF 233
>KRAF1_CAEEL (Q07292) Raf homolog serine/threonine-protein kinase (EC 2.7.11.1)| (Abnormal cell lineage protein 45) Length = 813 Score = 40.8 bits (94), Expect = 0.003 Identities = 20/64 (31%), Positives = 33/64 (51%) Frame = +1 Query: 412 FSEKQEIGRGGFAVVYEGSLLNVTVAVKKLTNLHMRDAPEVEYNREVECLMRVKHKNIVR 591 F + ++G G F VY G TVA+KKL + + + EV L + +H N++ Sbjct: 481 FIIQYKVGSGSFGTVYRGEFFG-TVAIKKLNVVDPTPSQMAAFKNEVAVLKKTRHLNVLL 539 Query: 592 FLGY 603 F+G+ Sbjct: 540 FMGW 543
>BUR1_CANGA (Q6FQ83) Serine/threonine-protein kinase BUR1 (EC 2.7.11.22) (EC| 2.7.11.23) Length = 667 Score = 40.8 bits (94), Expect = 0.003 Identities = 28/101 (27%), Positives = 48/101 (47%), Gaps = 10/101 (9%) Frame = +1 Query: 325 VEDLESMVIDESAEPKALPLSLLDE--------ITCGFSEKQEIGRGGFAVVYEGSLLNV 480 V+ L ++ IDE + L+ E + E++++G+G F VY+G L Sbjct: 23 VKSLPTVQIDEKTGDSYIELAPRSEGKIYGCTTFQGNYKEEEKLGQGTFGEVYKGLHLQT 82 Query: 481 T--VAVKKLTNLHMRDAPEVEYNREVECLMRVKHKNIVRFL 597 VA+K++ D + RE+ L R+ HKNI++ L Sbjct: 83 QRKVAMKRIIVNQENDLFPITAQREITILKRLNHKNIIKLL 123
>NORK_PEA (Q8LKZ1) Nodulation receptor kinase precursor (EC 2.7.11.1)| Length = 924 Score = 40.8 bits (94), Expect = 0.003 Identities = 24/65 (36%), Positives = 34/65 (52%), Gaps = 3/65 (4%) Frame = +1 Query: 421 KQEIGRGGFAVVYEGSL---LNVTVAVKKLTNLHMRDAPEVEYNREVECLMRVKHKNIVR 591 K IG GGF VY G+L V V V+ T+ E++ E+ L ++H+N+V Sbjct: 598 KTLIGEGGFGSVYRGTLDDGQEVAVKVRSATSTQGTR----EFDNELNLLSAIQHENLVP 653 Query: 592 FLGYC 606 LGYC Sbjct: 654 LLGYC 658
>NTRK2_CHICK (Q91987) BDNF/NT-3 growth factors receptor precursor (EC 2.7.10.1)| (Neurotrophic tyrosine kinase receptor type 2) (TrkB tyrosine kinase) (Trk-B) Length = 818 Score = 40.4 bits (93), Expect = 0.004 Identities = 23/71 (32%), Positives = 37/71 (52%), Gaps = 7/71 (9%) Frame = +1 Query: 421 KQEIGRGGFAVVYEGSLLN-------VTVAVKKLTNLHMRDAPEVEYNREVECLMRVKHK 579 K+E+G G F V+ N + VAVK L + D +++RE E L ++H+ Sbjct: 537 KRELGEGAFGKVFLAECYNLCPEQDKILVAVKTLKDAS--DNARKDFHREAELLTNLQHE 594 Query: 580 NIVRFLGYCAD 612 +IV+F G C + Sbjct: 595 HIVKFYGVCVE 605
>NAK_ARATH (P43293) Probable serine/threonine-protein kinase NAK (EC 2.7.11.1)| Length = 389 Score = 40.4 bits (93), Expect = 0.004 Identities = 26/97 (26%), Positives = 44/97 (45%), Gaps = 11/97 (11%) Frame = +1 Query: 355 ESAEPKALPLSLLDEITCGFSEKQEIGRGGFAVVYEGSL-----------LNVTVAVKKL 501 ++A K LS L T F +G GGF V++G + + +AVK+L Sbjct: 49 QNANLKNFSLSELKSATRNFRPDSVVGEGGFGCVFKGWIDESSLAPSKPGTGIVIAVKRL 108 Query: 502 TNLHMRDAPEVEYNREVECLMRVKHKNIVRFLGYCAD 612 + E+ E+ L ++ H N+V+ +GYC + Sbjct: 109 NQEGFQG--HREWLAEINYLGQLDHPNLVKLIGYCLE 143
>NTRK2_RAT (Q63604) BDNF/NT-3 growth factors receptor precursor (EC 2.7.10.1)| (Neurotrophic tyrosine kinase receptor type 2) (TrkB tyrosine kinase) (GP145-TrkB/GP95-TrkB) (Trk-B) Length = 821 Score = 40.4 bits (93), Expect = 0.004 Identities = 23/71 (32%), Positives = 37/71 (52%), Gaps = 7/71 (9%) Frame = +1 Query: 421 KQEIGRGGFAVVYEGSLLN-------VTVAVKKLTNLHMRDAPEVEYNREVECLMRVKHK 579 K+E+G G F V+ N + VAVK L + D +++RE E L ++H+ Sbjct: 540 KRELGEGAFGKVFLAECYNLCPEQDKILVAVKTLKDAS--DNARKDFHREAELLTNLQHE 597 Query: 580 NIVRFLGYCAD 612 +IV+F G C + Sbjct: 598 HIVKFYGVCVE 608
>NTRK2_MOUSE (P15209) BDNF/NT-3 growth factors receptor precursor (EC 2.7.10.1)| (Neurotrophic tyrosine kinase receptor type 2) (TrkB tyrosine kinase) (GP145-TrkB/GP95-TrkB) (Trk-B) Length = 821 Score = 40.4 bits (93), Expect = 0.004 Identities = 23/71 (32%), Positives = 37/71 (52%), Gaps = 7/71 (9%) Frame = +1 Query: 421 KQEIGRGGFAVVYEGSLLN-------VTVAVKKLTNLHMRDAPEVEYNREVECLMRVKHK 579 K+E+G G F V+ N + VAVK L + D +++RE E L ++H+ Sbjct: 540 KRELGEGAFGKVFLAECYNLCPEQDKILVAVKTLKDAS--DNARKDFHREAELLTNLQHE 597 Query: 580 NIVRFLGYCAD 612 +IV+F G C + Sbjct: 598 HIVKFYGVCVE 608
>NTRK2_HUMAN (Q16620) BDNF/NT-3 growth factors receptor precursor (EC 2.7.10.1)| (Neurotrophic tyrosine kinase receptor type 2) (TrkB tyrosine kinase) (GP145-TrkB) (Trk-B) Length = 822 Score = 40.4 bits (93), Expect = 0.004 Identities = 23/71 (32%), Positives = 37/71 (52%), Gaps = 7/71 (9%) Frame = +1 Query: 421 KQEIGRGGFAVVYEGSLLN-------VTVAVKKLTNLHMRDAPEVEYNREVECLMRVKHK 579 K+E+G G F V+ N + VAVK L + D +++RE E L ++H+ Sbjct: 541 KRELGEGAFGKVFLAECYNLCPEQDKILVAVKTLKDAS--DNARKDFHREAELLTNLQHE 598 Query: 580 NIVRFLGYCAD 612 +IV+F G C + Sbjct: 599 HIVKFYGVCVE 609
>ATG1_ASHGO (Q75CH3) Serine/threonine-protein kinase ATG1 (EC 2.7.11.1)| (Autophagy-related protein 1) Length = 972 Score = 40.4 bits (93), Expect = 0.004 Identities = 26/64 (40%), Positives = 41/64 (64%), Gaps = 5/64 (7%) Frame = +1 Query: 421 KQEIGRGGFAVVYEGSLLNVT---VAVKKLTNLHMRDAPEVEYNREVE--CLMRVKHKNI 585 ++EIGRG FAVVY+G L + + VA+K ++ +R+ +E N E+E L ++KH +I Sbjct: 21 EKEIGRGSFAVVYKGHLADSSAGNVAIKAVSRSKLRNKKLLE-NLEIEIAILKKIKHPHI 79 Query: 586 VRFL 597 V L Sbjct: 80 VGLL 83
>NEK6_MOUSE (Q9ES70) Serine/threonine-protein kinase Nek6 (EC 2.7.11.1)| (NimA-related protein kinase 6) Length = 313 Score = 40.4 bits (93), Expect = 0.004 Identities = 27/82 (32%), Positives = 47/82 (57%), Gaps = 4/82 (4%) Frame = +1 Query: 364 EPKALPLSLLDEITCG-FSEKQEIGRGGFAVVYEGSLL--NVTVAVKKLTNLHMRDA-PE 531 +P+ LP +L + F +++IGRG F+ VY+ + L TVA+KK+ M DA Sbjct: 28 DPQRLPNTLSFRCSLADFQIEKKIGRGQFSEVYKATCLLDRKTVALKKVQIFEMMDAKAR 87 Query: 532 VEYNREVECLMRVKHKNIVRFL 597 + +E+ L ++ H NI+++L Sbjct: 88 QDCVKEIGLLKQLNHPNIIKYL 109
>KPEL_DROME (Q05652) Probable serine/threonine-protein kinase pelle (EC| 2.7.11.1) Length = 501 Score = 40.0 bits (92), Expect = 0.005 Identities = 22/75 (29%), Positives = 37/75 (49%), Gaps = 4/75 (5%) Frame = +1 Query: 391 LDEITCGFSEKQEIGRGGFAVVYEGSLLNVTVAVKKLT----NLHMRDAPEVEYNREVEC 558 L+ T G+S +G+GGF VY G + VA+K + N+ + + E++ Sbjct: 206 LENATDGWSPDNRLGQGGFGDVYRGKWKQLDVAIKVMNYRSPNIDQKMVELQQSYNELKY 265 Query: 559 LMRVKHKNIVRFLGY 603 L ++H NI+ GY Sbjct: 266 LNSIRHDNILALYGY 280
>ABL_MLVAB (P00521) Tyrosine-protein kinase transforming protein Abl (EC| 2.7.10.2) (V-abl) Length = 746 Score = 40.0 bits (92), Expect = 0.005 Identities = 25/65 (38%), Positives = 36/65 (55%), Gaps = 3/65 (4%) Frame = +1 Query: 421 KQEIGRGGFAVVYEG--SLLNVTVAVKKLTNLHMRDAPEVE-YNREVECLMRVKHKNIVR 591 K ++G G + VYEG ++TVAVK L D EVE + +E + +KH N+V+ Sbjct: 131 KHKLGGGQYGEVYEGVWKKYSLTVAVKTLKE----DTMEVEEFLKEAAVMKEIKHPNLVQ 186 Query: 592 FLGYC 606 LG C Sbjct: 187 LLGVC 191
>ABL1_HUMAN (P00519) Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2)| (p150) (c-ABL) (Abelson murine leukemia viral oncogene homolog 1) Length = 1130 Score = 40.0 bits (92), Expect = 0.005 Identities = 25/65 (38%), Positives = 36/65 (55%), Gaps = 3/65 (4%) Frame = +1 Query: 421 KQEIGRGGFAVVYEG--SLLNVTVAVKKLTNLHMRDAPEVE-YNREVECLMRVKHKNIVR 591 K ++G G + VYEG ++TVAVK L D EVE + +E + +KH N+V+ Sbjct: 245 KHKLGGGQYGEVYEGVWKKYSLTVAVKTLKE----DTMEVEEFLKEAAVMKEIKHPNLVQ 300 Query: 592 FLGYC 606 LG C Sbjct: 301 LLGVC 305
>ABL_FSVHY (P10447) Tyrosine-protein kinase transforming protein Abl (EC| 2.7.10.2) (V-abl) Length = 439 Score = 40.0 bits (92), Expect = 0.005 Identities = 25/65 (38%), Positives = 36/65 (55%), Gaps = 3/65 (4%) Frame = +1 Query: 421 KQEIGRGGFAVVYEG--SLLNVTVAVKKLTNLHMRDAPEVE-YNREVECLMRVKHKNIVR 591 K ++G G + VYEG ++TVAVK L D EVE + +E + +KH N+V+ Sbjct: 194 KHKLGGGQYGEVYEGVWKKYSLTVAVKTLKE----DTMEVEEFLKEAAVMKEIKHPNLVQ 249 Query: 592 FLGYC 606 LG C Sbjct: 250 LLGVC 254
>TNI3K_HUMAN (Q59H18) Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1)| (TNNI3-interacting kinase) (Cardiac ankyrin repeat kinase) Length = 936 Score = 40.0 bits (92), Expect = 0.005 Identities = 30/102 (29%), Positives = 48/102 (47%), Gaps = 4/102 (3%) Frame = +1 Query: 313 IPSTVEDLESMVIDESAEPKALPLSLLDEITCGFSE---KQEIGRGGFAVVYEGSLLNVT 483 +PS + ++SM E A+ L L SE + IG G F VY+G N Sbjct: 529 VPSPLGKIKSMT-KEKADILLLRAGLPSHFHLQLSEIEFHEIIGSGSFGKVYKGRCRNKI 587 Query: 484 VAVKKL-TNLHMRDAPEVEYNREVECLMRVKHKNIVRFLGYC 606 VA+K+ N + + + REV L ++ H +++F+G C Sbjct: 588 VAIKRYRANTYCSKSDVDMFCREVSILCQLNHPCVIQFVGAC 629
>ABL1_MOUSE (P00520) Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2)| (p150) (c-ABL) (Abelson murine leukemia viral oncogene homolog 1) Length = 1123 Score = 40.0 bits (92), Expect = 0.005 Identities = 25/65 (38%), Positives = 36/65 (55%), Gaps = 3/65 (4%) Frame = +1 Query: 421 KQEIGRGGFAVVYEG--SLLNVTVAVKKLTNLHMRDAPEVE-YNREVECLMRVKHKNIVR 591 K ++G G + VYEG ++TVAVK L D EVE + +E + +KH N+V+ Sbjct: 245 KHKLGGGQYGEVYEGVWKKYSLTVAVKTLKE----DTMEVEEFLKEAAVMKEIKHPNLVQ 300 Query: 592 FLGYC 606 LG C Sbjct: 301 LLGVC 305
>TNI3K_PONPY (Q5RF15) Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1)| (TNNI3-interacting kinase) Length = 617 Score = 40.0 bits (92), Expect = 0.005 Identities = 30/102 (29%), Positives = 48/102 (47%), Gaps = 4/102 (3%) Frame = +1 Query: 313 IPSTVEDLESMVIDESAEPKALPLSLLDEITCGFSE---KQEIGRGGFAVVYEGSLLNVT 483 +PS + ++SM E A+ L L SE + IG G F VY+G N Sbjct: 427 VPSPLGKIKSMT-KEKADILLLRAGLPSHFHLQLSEIEFHEIIGSGSFGKVYKGRCRNKI 485 Query: 484 VAVKKL-TNLHMRDAPEVEYNREVECLMRVKHKNIVRFLGYC 606 VA+K+ N + + + REV L ++ H +++F+G C Sbjct: 486 VAIKRYRANTYCSKSDVDMFCREVSILCQLNHPCVIQFVGAC 527
>WNK1_MOUSE (P83741) Serine/threonine-protein kinase WNK1 (EC 2.7.11.1)| (Protein kinase with no lysine 1) (Protein kinase, lysine-deficient 1) Length = 2377 Score = 39.7 bits (91), Expect = 0.007 Identities = 29/102 (28%), Positives = 44/102 (43%), Gaps = 2/102 (1%) Frame = +1 Query: 295 QMDIQMIPSTVEDLESMVIDESAEPKALPLSLLDEITCGFSEKQEIGRGGFAVVYEGSLL 474 Q D +E+LE+ + S + + L + EIGRG F VY+G Sbjct: 194 QEDRSQQQDDIEELETKAVGMSNDGRFLKFDI------------EIGRGSFKTVYKGLDT 241 Query: 475 NVTVAVK--KLTNLHMRDAPEVEYNREVECLMRVKHKNIVRF 594 TV V +L + + + + E E L ++H NIVRF Sbjct: 242 ETTVEVAWCELQDRKLTKSERQRFKEEAEMLKGLQHPNIVRF 283
>RLCK7_ARATH (Q9LQQ8) Probable serine/threonine-protein kinase RLCKVII (EC| 2.7.11.1) Length = 423 Score = 39.7 bits (91), Expect = 0.007 Identities = 25/76 (32%), Positives = 41/76 (53%), Gaps = 2/76 (2%) Frame = +1 Query: 391 LDEITCGFSEKQEIGRGGFAVVYEGSL--LNVTVAVKKLTNLHMRDAPEVEYNREVECLM 564 L E T F +G GGF V++G++ L+ VA+K+L ++ E + EV L Sbjct: 96 LAEATGNFRSDCFLGEGGFGKVFKGTIEKLDQVVAIKQLDRNGVQGIRE--FVVEVLTLS 153 Query: 565 RVKHKNIVRFLGYCAD 612 H N+V+ +G+CA+ Sbjct: 154 LADHPNLVKLIGFCAE 169
>BUR1_YEAST (P23293) Serine/threonine-protein kinase BUR1 (EC 2.7.11.22) (EC| 2.7.11.23) (Suppressor of GPA1-Vall50 mutation protein 1) (Bypass UAS requirement protein 1) Length = 657 Score = 39.7 bits (91), Expect = 0.007 Identities = 21/64 (32%), Positives = 36/64 (56%), Gaps = 2/64 (3%) Frame = +1 Query: 412 FSEKQEIGRGGFAVVYEGSLLNVT--VAVKKLTNLHMRDAPEVEYNREVECLMRVKHKNI 585 + E +++G+G F VY+G L VA+KK+ +D + RE+ L R+ HKNI Sbjct: 60 YREDEKLGQGTFGEVYKGIHLETQRQVAMKKIIVSVEKDLFPITAQREITILKRLNHKNI 119 Query: 586 VRFL 597 ++ + Sbjct: 120 IKLI 123
>WNK1_HUMAN (Q9H4A3) Serine/threonine-protein kinase WNK1 (EC 2.7.11.1)| (Protein kinase with no lysine 1) (Protein kinase, lysine-deficient 1) (Kinase deficient protein) Length = 2382 Score = 39.3 bits (90), Expect = 0.009 Identities = 27/92 (29%), Positives = 42/92 (45%), Gaps = 2/92 (2%) Frame = +1 Query: 325 VEDLESMVIDESAEPKALPLSLLDEITCGFSEKQEIGRGGFAVVYEGSLLNVTVAVK--K 498 +E+LE+ + S + + L + EIGRG F VY+G TV V + Sbjct: 204 IEELETKAVGMSNDGRFLKFDI------------EIGRGSFKTVYKGLDTETTVEVAWCE 251 Query: 499 LTNLHMRDAPEVEYNREVECLMRVKHKNIVRF 594 L + + + + E E L ++H NIVRF Sbjct: 252 LQDRKLTKSERQRFKEEAEMLKGLQHPNIVRF 283
>SHARK_DROME (Q24145) Tyrosine-protein kinase shark (EC 2.7.10.2)| Length = 939 Score = 39.3 bits (90), Expect = 0.009 Identities = 25/68 (36%), Positives = 37/68 (54%), Gaps = 9/68 (13%) Frame = +1 Query: 424 QEIGRGGFAVVYEGSLLN---------VTVAVKKLTNLHMRDAPEVEYNREVECLMRVKH 576 +EIG G F V+ G LL + VA+K L++ H + E+ RE +MR++H Sbjct: 666 REIGHGEFGSVHSGWLLRKSGAGEESRLEVAIKMLSDEHSN---KQEFLREASVMMRLEH 722 Query: 577 KNIVRFLG 600 K IVR +G Sbjct: 723 KCIVRLIG 730
>WNK1_RAT (Q9JIH7) Serine/threonine-protein kinase WNK1 (EC 2.7.11.1)| (Protein kinase with no lysine 1) (Protein kinase, lysine-deficient 1) Length = 2126 Score = 39.3 bits (90), Expect = 0.009 Identities = 27/92 (29%), Positives = 42/92 (45%), Gaps = 2/92 (2%) Frame = +1 Query: 325 VEDLESMVIDESAEPKALPLSLLDEITCGFSEKQEIGRGGFAVVYEGSLLNVTVAVK--K 498 +E+LE+ + S + + L + EIGRG F VY+G TV V + Sbjct: 204 IEELETKAVGMSNDGRFLKFDI------------EIGRGSFKTVYKGLDTETTVEVAWCE 251 Query: 499 LTNLHMRDAPEVEYNREVECLMRVKHKNIVRF 594 L + + + + E E L ++H NIVRF Sbjct: 252 LQDRKLTKSERQRFKEEAEMLKGLQHPNIVRF 283
>NEK6_RAT (P59895) Serine/threonine-protein kinase Nek6 (EC 2.7.11.1)| (NimA-related protein kinase 6) Length = 313 Score = 38.9 bits (89), Expect = 0.012 Identities = 23/65 (35%), Positives = 39/65 (60%), Gaps = 3/65 (4%) Frame = +1 Query: 412 FSEKQEIGRGGFAVVYEGSLL--NVTVAVKKLTNLHMRDA-PEVEYNREVECLMRVKHKN 582 F +++IGRG F+ VY+ + L TVA+KK+ M DA + +E+ L ++ H N Sbjct: 45 FQIEKKIGRGQFSEVYKATCLLDRKTVALKKVQIFEMMDAKARQDCVKEIGLLKQLNHPN 104 Query: 583 IVRFL 597 I+++L Sbjct: 105 IIKYL 109
>NEK6_HUMAN (Q9HC98) Serine/threonine-protein kinase Nek6 (EC 2.7.11.1)| (NimA-related protein kinase 6) (Protein kinase SID6-1512) Length = 313 Score = 38.9 bits (89), Expect = 0.012 Identities = 23/65 (35%), Positives = 39/65 (60%), Gaps = 3/65 (4%) Frame = +1 Query: 412 FSEKQEIGRGGFAVVYEGSLL--NVTVAVKKLTNLHMRDA-PEVEYNREVECLMRVKHKN 582 F +++IGRG F+ VY+ + L TVA+KK+ M DA + +E+ L ++ H N Sbjct: 45 FQIEKKIGRGQFSEVYKATCLLDRKTVALKKVQIFEMMDAKARQDCVKEIGLLKQLNHPN 104 Query: 583 IVRFL 597 I+++L Sbjct: 105 IIKYL 109
>JAK2_RAT (Q62689) Tyrosine-protein kinase JAK2 (EC 2.7.10.2) (Janus kinase 2)| (JAK-2) Length = 1132 Score = 38.9 bits (89), Expect = 0.012 Identities = 27/70 (38%), Positives = 38/70 (54%), Gaps = 9/70 (12%) Frame = +1 Query: 424 QEIGRGGFAVV----YEGSLLNV--TVAVKKL---TNLHMRDAPEVEYNREVECLMRVKH 576 Q++G+G F V Y+ N VAVKKL T H+RD + RE+E L ++H Sbjct: 853 QQLGKGNFGSVEMCRYDPLQDNTGEVVAVKKLQHSTEEHLRD-----FEREIEILKSLQH 907 Query: 577 KNIVRFLGYC 606 NIV++ G C Sbjct: 908 DNIVKYKGVC 917
>JAK2_HUMAN (O60674) Tyrosine-protein kinase JAK2 (EC 2.7.10.2) (Janus kinase 2)| (JAK-2) Length = 1132 Score = 38.9 bits (89), Expect = 0.012 Identities = 27/70 (38%), Positives = 38/70 (54%), Gaps = 9/70 (12%) Frame = +1 Query: 424 QEIGRGGFAVV----YEGSLLNV--TVAVKKL---TNLHMRDAPEVEYNREVECLMRVKH 576 Q++G+G F V Y+ N VAVKKL T H+RD + RE+E L ++H Sbjct: 853 QQLGKGNFGSVEMCRYDPLQDNTGEVVAVKKLQHSTEEHLRD-----FEREIEILKSLQH 907 Query: 577 KNIVRFLGYC 606 NIV++ G C Sbjct: 908 DNIVKYKGVC 917
>JAK2_MOUSE (Q62120) Tyrosine-protein kinase JAK2 (EC 2.7.10.2) (Janus kinase 2)| (JAK-2) Length = 1129 Score = 38.9 bits (89), Expect = 0.012 Identities = 27/70 (38%), Positives = 38/70 (54%), Gaps = 9/70 (12%) Frame = +1 Query: 424 QEIGRGGFAVV----YEGSLLNV--TVAVKKL---TNLHMRDAPEVEYNREVECLMRVKH 576 Q++G+G F V Y+ N VAVKKL T H+RD + RE+E L ++H Sbjct: 853 QQLGKGNFGSVEMCRYDPLQDNTGEVVAVKKLQHSTEEHLRD-----FEREIEILKSLQH 907 Query: 577 KNIVRFLGYC 606 NIV++ G C Sbjct: 908 DNIVKYKGVC 917
>FES_FELCA (P14238) Proto-oncogene tyrosine-protein kinase FES/FPS (EC| 2.7.10.2) (C-FES) Length = 820 Score = 38.5 bits (88), Expect = 0.016 Identities = 23/63 (36%), Positives = 33/63 (52%), Gaps = 2/63 (3%) Frame = +1 Query: 424 QEIGRGGFAVVYEGSLL--NVTVAVKKLTNLHMRDAPEVEYNREVECLMRVKHKNIVRFL 597 ++IGRG F V+ G L N VAVK D + ++ +E + L + H NIVR + Sbjct: 563 EQIGRGNFGEVFSGRLRADNTLVAVKSCRETLPPDI-KAKFLQEAKILKQYSHPNIVRLI 621 Query: 598 GYC 606 G C Sbjct: 622 GVC 624
>FES_FSVGA (P00542) Tyrosine-protein kinase transforming protein Fes (EC| 2.7.10.2) Length = 609 Score = 38.5 bits (88), Expect = 0.016 Identities = 23/63 (36%), Positives = 33/63 (52%), Gaps = 2/63 (3%) Frame = +1 Query: 424 QEIGRGGFAVVYEGSLL--NVTVAVKKLTNLHMRDAPEVEYNREVECLMRVKHKNIVRFL 597 ++IGRG F V+ G L N VAVK D + ++ +E + L + H NIVR + Sbjct: 352 EQIGRGNFGEVFSGRLRADNTLVAVKSCRETLPPDI-KAKFLQEAKILKQYSHPNIVRLI 410 Query: 598 GYC 606 G C Sbjct: 411 GVC 413
>NEK7_MOUSE (Q9ES74) Serine/threonine-protein kinase Nek7 (EC 2.7.11.1)| (NimA-related protein kinase 7) Length = 302 Score = 38.5 bits (88), Expect = 0.016 Identities = 24/78 (30%), Positives = 42/78 (53%), Gaps = 3/78 (3%) Frame = +1 Query: 370 KALPLSLLDEITCGFSEKQEIGRGGFAVVYEGSLL--NVTVAVKKLTNLHMRDA-PEVEY 540 KAL + F +++IGRG F+ VY S L V VA+KK+ + DA + Sbjct: 20 KALRPDMGYNTLANFRIEKKIGRGQFSEVYRASCLLDGVPVALKKVQIFDLMDAKARADC 79 Query: 541 NREVECLMRVKHKNIVRF 594 +E++ L ++ H N++++ Sbjct: 80 IKEIDLLKQLNHPNVIKY 97
>ATG1_PICPA (Q8TGI1) Serine/threonine-protein kinase ATG1 (EC 2.7.11.1)| (Autophagy-related protein 1) (Glucose-induced selective autophagy protein 10) (Pexophagy zeocin-resistant mutant protein 1) Length = 796 Score = 38.5 bits (88), Expect = 0.016 Identities = 26/61 (42%), Positives = 36/61 (59%), Gaps = 4/61 (6%) Frame = +1 Query: 427 EIGRGGFAVVYEG--SLLNVTVAVKKLTNLHMRDAPEVEYNREVE--CLMRVKHKNIVRF 594 EIGRG FA VY+G S V+VA+K + +R+ +E N EVE L +KH ++V Sbjct: 14 EIGRGSFANVYKGYNSKTQVSVAIKSVIKSRLRNKKLIE-NLEVEISILKNLKHPHVVAL 72 Query: 595 L 597 L Sbjct: 73 L 73
>FER_HUMAN (P16591) Proto-oncogene tyrosine-protein kinase FER (EC 2.7.10.2)| (p94-FER) (c-FER) Length = 822 Score = 38.5 bits (88), Expect = 0.016 Identities = 17/59 (28%), Positives = 32/59 (54%) Frame = +1 Query: 430 IGRGGFAVVYEGSLLNVTVAVKKLTNLHMRDAPEVEYNREVECLMRVKHKNIVRFLGYC 606 +G+G F VY+G+L + T K + ++++ +E + L + H NIV+ +G C Sbjct: 569 LGKGNFGEVYKGTLKDKTSVAVKTCKEDLPQELKIKFLQEAKILKQYDHPNIVKLIGVC 627
>FLK_RAT (P09760) Tyrosine-protein kinase FLK (EC 2.7.10.2) (Fragment)| Length = 323 Score = 38.5 bits (88), Expect = 0.016 Identities = 17/59 (28%), Positives = 32/59 (54%) Frame = +1 Query: 430 IGRGGFAVVYEGSLLNVTVAVKKLTNLHMRDAPEVEYNREVECLMRVKHKNIVRFLGYC 606 +G+G F VY+G+L + T K + ++++ +E + L + H NIV+ +G C Sbjct: 70 LGKGNFGEVYKGTLKDKTPVAVKTCKEDLPQELKIKFLQEAKILKQYDHPNIVKLIGVC 128
>FES_FSVST (P00543) Tyrosine-protein kinase transforming protein Fes (EC| 2.7.10.2) Length = 477 Score = 38.5 bits (88), Expect = 0.016 Identities = 23/63 (36%), Positives = 33/63 (52%), Gaps = 2/63 (3%) Frame = +1 Query: 424 QEIGRGGFAVVYEGSLL--NVTVAVKKLTNLHMRDAPEVEYNREVECLMRVKHKNIVRFL 597 ++IGRG F V+ G L N VAVK D + ++ +E + L + H NIVR + Sbjct: 220 EQIGRGNFGEVFSGRLRADNTLVAVKSCRETLPPDI-KAKFLQEAKILKQYSHPNIVRLI 278 Query: 598 GYC 606 G C Sbjct: 279 GVC 281
>APK1B_ARATH (P46573) Protein kinase APK1B, chloroplast precursor (EC 2.7.11.1)| Length = 412 Score = 38.1 bits (87), Expect = 0.021 Identities = 27/97 (27%), Positives = 42/97 (43%), Gaps = 11/97 (11%) Frame = +1 Query: 355 ESAEPKALPLSLLDEITCGFSEKQEIGRGGFAVVYEGSL-----------LNVTVAVKKL 501 +S K+ + L T F +G GGF V++G + V +AVKKL Sbjct: 50 QSPNLKSFTFAELKAATRNFRPDSVLGEGGFGSVFKGWIDEQTLTASKPGTGVVIAVKKL 109 Query: 502 TNLHMRDAPEVEYNREVECLMRVKHKNIVRFLGYCAD 612 + E+ EV L + H N+V+ +GYC + Sbjct: 110 NQDGWQG--HQEWLAEVNYLGQFSHPNLVKLIGYCLE 144
>FES_MOUSE (P16879) Proto-oncogene tyrosine-protein kinase Fes/Fps (EC| 2.7.10.2) (C-Fes) Length = 820 Score = 38.1 bits (87), Expect = 0.021 Identities = 23/63 (36%), Positives = 32/63 (50%), Gaps = 2/63 (3%) Frame = +1 Query: 424 QEIGRGGFAVVYEGSLL--NVTVAVKKLTNLHMRDAPEVEYNREVECLMRVKHKNIVRFL 597 ++IGRG F V+ G L N VAVK D + ++ +E L + H NIVR + Sbjct: 563 EQIGRGNFGEVFSGRLRADNTPVAVKSCRETLPPDL-KAKFLQEARILKQYNHPNIVRLI 621 Query: 598 GYC 606 G C Sbjct: 622 GVC 624
>ATG1_KLULA (Q6CSX2) Serine/threonine-protein kinase ATG1 (EC 2.7.11.1)| (Autophagy-related protein 1) Length = 831 Score = 38.1 bits (87), Expect = 0.021 Identities = 25/66 (37%), Positives = 41/66 (62%), Gaps = 4/66 (6%) Frame = +1 Query: 403 TCGFSEKQEIGRGGFAVVYEGSLL--NVTVAVKKLTNLHMRDAPEVEYNREVE--CLMRV 570 T +S ++EIG+G FAVVY+G L +A+K ++ +++ +E N EVE L ++ Sbjct: 18 TENYSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSKLKNKKLLE-NLEVEIAILKKI 76 Query: 571 KHKNIV 588 KH +IV Sbjct: 77 KHPHIV 82
>FES_HUMAN (P07332) Proto-oncogene tyrosine-protein kinase Fes/Fps (EC| 2.7.10.2) (C-Fes) Length = 822 Score = 38.1 bits (87), Expect = 0.021 Identities = 23/63 (36%), Positives = 32/63 (50%), Gaps = 2/63 (3%) Frame = +1 Query: 424 QEIGRGGFAVVYEGSLL--NVTVAVKKLTNLHMRDAPEVEYNREVECLMRVKHKNIVRFL 597 ++IGRG F V+ G L N VAVK D + ++ +E L + H NIVR + Sbjct: 565 EQIGRGNFGEVFSGRLRADNTLVAVKSCRETLPPDL-KAKFLQEARILKQYSHPNIVRLI 623 Query: 598 GYC 606 G C Sbjct: 624 GVC 626
>NTRK1_RAT (P35739) High affinity nerve growth factor receptor precursor (EC| 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 1) (p140-TrkA) (Slow nerve growth factor receptor) (Trk-A) Length = 799 Score = 37.7 bits (86), Expect = 0.027 Identities = 23/71 (32%), Positives = 35/71 (49%), Gaps = 7/71 (9%) Frame = +1 Query: 421 KQEIGRGGFAVVYEGSLLNVT-------VAVKKLTNLHMRDAPEVEYNREVECLMRVKHK 579 K E+G G F V+ N+ VAVK L + +++RE E L ++H+ Sbjct: 516 KWELGEGAFGKVFLAECYNLLNDQDKMLVAVKALKETS--ENARQDFHREAELLTMLQHQ 573 Query: 580 NIVRFLGYCAD 612 +IVRF G C + Sbjct: 574 HIVRFFGVCTE 584
>MERTK_RAT (P57097) Proto-oncogene tyrosine-protein kinase MER precursor (EC| 2.7.10.1) (C-mer) (Receptor tyrosine kinase MerTK) Length = 994 Score = 37.7 bits (86), Expect = 0.027 Identities = 22/68 (32%), Positives = 31/68 (45%), Gaps = 7/68 (10%) Frame = +1 Query: 430 IGRGGFAVVYEGSLLN-------VTVAVKKLTNLHMRDAPEVEYNREVECLMRVKHKNIV 588 +G G F V EG+L V V KL N +R+ E + E C+ H N++ Sbjct: 588 LGEGEFGSVMEGNLKQEDGTSQKVAVKTMKLDNFSLREIEE--FLSEAACMKDFNHPNVI 645 Query: 589 RFLGYCAD 612 R LG C + Sbjct: 646 RLLGVCIE 653
>IRAK2_HUMAN (O43187) Interleukin-1 receptor-associated kinase-like 2 (IRAK-2)| Length = 590 Score = 37.7 bits (86), Expect = 0.027 Identities = 21/73 (28%), Positives = 35/73 (47%), Gaps = 2/73 (2%) Frame = +1 Query: 397 EITCGFSEKQEIGRGGFAVVYEGSLLNVTVAVKKLTNLHMRDAPEVE--YNREVECLMRV 570 + T F++ ++I +G FA VY G KKL +E + E++ +R Sbjct: 205 QATDDFNQNRKISQGTFADVYRGHRHGKPFVFKKLRETACSSPGSIERFFQAELQICLRC 264 Query: 571 KHKNIVRFLGYCA 609 H N++ LG+CA Sbjct: 265 CHPNVLPVLGFCA 277
>NTRK1_HUMAN (P04629) High affinity nerve growth factor receptor precursor (EC| 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 1) (TRK1 transforming tyrosine kinase protein) (p140-TrkA) (Trk-A) Length = 796 Score = 37.7 bits (86), Expect = 0.027 Identities = 23/71 (32%), Positives = 35/71 (49%), Gaps = 7/71 (9%) Frame = +1 Query: 421 KQEIGRGGFAVVYEGSLLNVT-------VAVKKLTNLHMRDAPEVEYNREVECLMRVKHK 579 K E+G G F V+ N+ VAVK L ++ ++ RE E L ++H+ Sbjct: 513 KWELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKEAS--ESARQDFQREAELLTMLQHQ 570 Query: 580 NIVRFLGYCAD 612 +IVRF G C + Sbjct: 571 HIVRFFGVCTE 581
>MERTK_HUMAN (Q12866) Proto-oncogene tyrosine-protein kinase MER precursor (EC| 2.7.10.1) (C-mer) (Receptor tyrosine kinase MerTK) Length = 999 Score = 37.7 bits (86), Expect = 0.027 Identities = 23/68 (33%), Positives = 31/68 (45%), Gaps = 7/68 (10%) Frame = +1 Query: 430 IGRGGFAVVYEGSL-------LNVTVAVKKLTNLHMRDAPEVEYNREVECLMRVKHKNIV 588 +G G F V EG+L L V V KL N R+ E + E C+ H N++ Sbjct: 593 LGEGEFGSVMEGNLKQEDGTSLKVAVKTMKLDNSSHREIEE--FLSEAACMKDFSHPNVI 650 Query: 589 RFLGYCAD 612 R LG C + Sbjct: 651 RLLGVCIE 658
>PKN2_CLOAB (Q97IC2) Probable serine/threonine protein kinase CAC1728 (EC| 2.7.11.1) Length = 657 Score = 37.7 bits (86), Expect = 0.027 Identities = 27/67 (40%), Positives = 36/67 (53%), Gaps = 3/67 (4%) Frame = +1 Query: 421 KQEIGRGGFAVVYEG--SLLNVTVAVKKLTNLHMRDAPEV-EYNREVECLMRVKHKNIVR 591 ++EIG GG AVVY+ +LLN VAVK L + D V ++ RE R+ + NIV Sbjct: 13 EEEIGVGGTAVVYKAMDTLLNRHVAVKVLKHEFTEDEEFVFKFKREASAAARIANANIVN 72 Query: 592 FLGYCAD 612 AD Sbjct: 73 IYDVGAD 79
>AVR2A_SHEEP (Q28560) Activin receptor type 2A precursor (EC 2.7.11.30) (Activin| receptor type IIA) (ACTR-IIA) Length = 513 Score = 37.7 bits (86), Expect = 0.027 Identities = 22/55 (40%), Positives = 32/55 (58%) Frame = +1 Query: 436 RGGFAVVYEGSLLNVTVAVKKLTNLHMRDAPEVEYNREVECLMRVKHKNIVRFLG 600 RGGF V++ LLN VAVK ++D + EV L +KH+NI++F+G Sbjct: 200 RGGFGCVWKAQLLNEYVAVKIFP---IQDKQSWQNEYEVYSLPGMKHENILQFIG 251
>KIN28_YEAST (P06242) Serine/threonine-protein kinase KIN28 (EC 2.7.11.23)| Length = 306 Score = 37.7 bits (86), Expect = 0.027 Identities = 16/69 (23%), Positives = 40/69 (57%), Gaps = 2/69 (2%) Frame = +1 Query: 397 EITCGFSEKQEIGRGGFAVVYEGSLLNV--TVAVKKLTNLHMRDAPEVEYNREVECLMRV 570 ++ +++++++G G +AVVY G + +A+K++ +D ++ REV+ L + Sbjct: 2 KVNMEYTKEKKVGEGTYAVVYLGCQHSTGRKIAIKEIKTSEFKDGLDMSAIREVKYLQEM 61 Query: 571 KHKNIVRFL 597 +H N++ + Sbjct: 62 QHPNVIELI 70
>CC2H1_TRYCO (P54664) Cell division control protein 2 homolog 1 (EC 2.7.11.22)| Length = 301 Score = 37.7 bits (86), Expect = 0.027 Identities = 20/67 (29%), Positives = 35/67 (52%), Gaps = 2/67 (2%) Frame = +1 Query: 412 FSEKQEIGRGGFAVVYEGSLL--NVTVAVKKLTNLHMRDAPEVEYNREVECLMRVKHKNI 585 + ++IG G + VVY + +V VA+K++ + + RE+ L ++H+NI Sbjct: 5 YQRLEKIGEGSYGVVYRARDITTDVIVALKRIRLESVEEGVPCTAIREISILKELRHENI 64 Query: 586 VRFLGYC 606 VR L C Sbjct: 65 VRLLDVC 71
>ABL2_HUMAN (P42684) Tyrosine-protein kinase ABL2 (EC 2.7.10.2) (Abelson murine| leukemia viral oncogene homolog 2) (Tyrosine kinase ARG) Length = 1182 Score = 37.4 bits (85), Expect = 0.035 Identities = 24/65 (36%), Positives = 35/65 (53%), Gaps = 3/65 (4%) Frame = +1 Query: 421 KQEIGRGGFAVVYEG--SLLNVTVAVKKLTNLHMRDAPEVE-YNREVECLMRVKHKNIVR 591 K ++G G + VY G ++TVAVK L D EVE + +E + +KH N+V+ Sbjct: 291 KHKLGGGQYGEVYVGVWKKYSLTVAVKTLKE----DTMEVEEFLKEAAVMKEIKHPNLVQ 346 Query: 592 FLGYC 606 LG C Sbjct: 347 LLGVC 351
>NEK7_HUMAN (Q8TDX7) Serine/threonine-protein kinase Nek7 (EC 2.7.11.1)| (NimA-related protein kinase 7) Length = 302 Score = 37.4 bits (85), Expect = 0.035 Identities = 23/78 (29%), Positives = 42/78 (53%), Gaps = 3/78 (3%) Frame = +1 Query: 370 KALPLSLLDEITCGFSEKQEIGRGGFAVVYEGSLL--NVTVAVKKLTNLHMRDA-PEVEY 540 KAL + F +++IGRG F+ VY + L V VA+KK+ + DA + Sbjct: 20 KALRPDMGYNTLANFRIEKKIGRGQFSEVYRAACLLDGVPVALKKVQIFDLMDAKARADC 79 Query: 541 NREVECLMRVKHKNIVRF 594 +E++ L ++ H N++++ Sbjct: 80 IKEIDLLKQLNHPNVIKY 97
>BUR1_ASHGO (Q75D46) Serine/threonine-protein kinase BUR1 (EC 2.7.11.22) (EC| 2.7.11.23) Length = 753 Score = 37.4 bits (85), Expect = 0.035 Identities = 20/64 (31%), Positives = 35/64 (54%), Gaps = 2/64 (3%) Frame = +1 Query: 412 FSEKQEIGRGGFAVVYEGSLLNVT--VAVKKLTNLHMRDAPEVEYNREVECLMRVKHKNI 585 + E++++G+G F VY G L VA+KK+ D + RE+ L R+ H+N+ Sbjct: 56 YKEEKKLGQGTFGEVYRGVHLATQRQVAMKKILVKTENDLFPITAQREITILKRLNHRNV 115 Query: 586 VRFL 597 V+ + Sbjct: 116 VQLI 119
>WNK3_HUMAN (Q9BYP7) Serine/threonine-protein kinase WNK3 (EC 2.7.11.1)| (Protein kinase with no lysine 3) (Protein kinase, lysine-deficient 3) Length = 1743 Score = 37.0 bits (84), Expect = 0.046 Identities = 22/58 (37%), Positives = 31/58 (53%), Gaps = 2/58 (3%) Frame = +1 Query: 427 EIGRGGFAVVYEGSLLN--VTVAVKKLTNLHMRDAPEVEYNREVECLMRVKHKNIVRF 594 E+GRG F VY+G V VA +L + + A + + E E L ++H NIVRF Sbjct: 152 ELGRGAFKTVYKGLDTETWVEVAWCELQDRKLTKAEQQRFKEEAEMLKGLQHPNIVRF 209
>MERTK_MOUSE (Q60805) Proto-oncogene tyrosine-protein kinase MER precursor (EC| 2.7.10.1) (C-mer) (Receptor tyrosine kinase MerTK) Length = 994 Score = 37.0 bits (84), Expect = 0.046 Identities = 22/68 (32%), Positives = 30/68 (44%), Gaps = 7/68 (10%) Frame = +1 Query: 430 IGRGGFAVVYEGSLLN-------VTVAVKKLTNLHMRDAPEVEYNREVECLMRVKHKNIV 588 +G G F V EG+L V V KL N R+ E + E C+ H N++ Sbjct: 588 LGEGEFGSVMEGNLKQEDGTSQKVAVKTMKLDNFSQREIEE--FLSEAACMKDFNHPNVI 645 Query: 589 RFLGYCAD 612 R LG C + Sbjct: 646 RLLGVCIE 653
>E2AK3_RAT (Q9Z1Z1) Eukaryotic translation initiation factor 2-alpha kinase 3| precursor (EC 2.7.11.1) (PRKR-like endoplasmic reticulum kinase) (Pancreatic eIF2-alpha kinase) Length = 1108 Score = 37.0 bits (84), Expect = 0.046 Identities = 23/70 (32%), Positives = 38/70 (54%), Gaps = 2/70 (2%) Frame = +1 Query: 412 FSEKQEIGRGGFAVVYEGS--LLNVTVAVKKLTNLHMRDAPEVEYNREVECLMRVKHKNI 585 F Q +GRGGF VV+E + + A+K++ L R+ + REV+ L +++H I Sbjct: 585 FEPIQCMGRGGFGVVFEAKNKVDDCNYAIKRI-RLPNRELAREKVMREVKALAKLEHPGI 643 Query: 586 VRFLGYCADT 615 VR+ +T Sbjct: 644 VRYFNAWLET 653
>CRK1_LEIME (Q06309) Cell division protein kinase 2 homolog CRK1 (EC 2.7.11.23)| Length = 301 Score = 37.0 bits (84), Expect = 0.046 Identities = 20/71 (28%), Positives = 37/71 (52%), Gaps = 2/71 (2%) Frame = +1 Query: 400 ITCGFSEKQEIGRGGFAVVYEG--SLLNVTVAVKKLTNLHMRDAPEVEYNREVECLMRVK 573 +T + +++IG G + VVY+ + TVA+K++ + RE+ L ++ Sbjct: 1 MTSRYERQEKIGEGTYGVVYKARDTSTAATVALKRIRLDSEEEGVPCTAIREISLLKELR 60 Query: 574 HKNIVRFLGYC 606 H+NIV+ L C Sbjct: 61 HENIVKLLDVC 71
>E2AK3_MOUSE (Q9Z2B5) Eukaryotic translation initiation factor 2-alpha kinase 3| precursor (EC 2.7.11.1) (PRKR-like endoplasmic reticulum kinase) (Pancreatic eIF2-alpha kinase) Length = 1114 Score = 37.0 bits (84), Expect = 0.046 Identities = 23/70 (32%), Positives = 38/70 (54%), Gaps = 2/70 (2%) Frame = +1 Query: 412 FSEKQEIGRGGFAVVYEGS--LLNVTVAVKKLTNLHMRDAPEVEYNREVECLMRVKHKNI 585 F Q +GRGGF VV+E + + A+K++ L R+ + REV+ L +++H I Sbjct: 589 FEPIQCMGRGGFGVVFEAKNKVDDCNYAIKRI-RLPNRELAREKVMREVKALAKLEHPGI 647 Query: 586 VRFLGYCADT 615 VR+ +T Sbjct: 648 VRYFNAWLET 657
>APK1A_ARATH (Q06548) Protein kinase APK1A, chloroplast precursor (EC 2.7.11.1)| Length = 410 Score = 37.0 bits (84), Expect = 0.046 Identities = 25/97 (25%), Positives = 43/97 (44%), Gaps = 11/97 (11%) Frame = +1 Query: 355 ESAEPKALPLSLLDEITCGFSEKQEIGRGGFAVVYEGSL-----------LNVTVAVKKL 501 +S K+ + L T F +G GGF V++G + + +AVKKL Sbjct: 49 QSPNLKSFSFAELKSATRNFRPDSVLGEGGFGCVFKGWIDEKSLTASRPGTGLVIAVKKL 108 Query: 502 TNLHMRDAPEVEYNREVECLMRVKHKNIVRFLGYCAD 612 + E+ EV L + H+++V+ +GYC + Sbjct: 109 NQDGWQG--HQEWLAEVNYLGQFSHRHLVKLIGYCLE 143
>TRK1_LYMST (O76997) Putative neurotrophin receptor LTRK 1 precursor (EC| 2.7.10.1) Length = 794 Score = 37.0 bits (84), Expect = 0.046 Identities = 23/69 (33%), Positives = 35/69 (50%), Gaps = 7/69 (10%) Frame = +1 Query: 430 IGRGGFAVVYEGSLLNVT-------VAVKKLTNLHMRDAPEVEYNREVECLMRVKHKNIV 588 IG G F V+ G+ ++ VAVK L D+ + ++ RE E L ++H NIV Sbjct: 510 IGEGAFGRVFLGTCAHLIQKNEFAIVAVKTLKG-SCSDSLKRDFEREAEMLATIEHANIV 568 Query: 589 RFLGYCADT 615 F G C ++ Sbjct: 569 TFYGVCTES 577
>M3K6_HUMAN (O95382) Mitogen-activated protein kinase kinase kinase 6 (EC| 2.7.11.25) Length = 1011 Score = 37.0 bits (84), Expect = 0.046 Identities = 30/99 (30%), Positives = 49/99 (49%), Gaps = 2/99 (2%) Frame = +1 Query: 310 MIPSTVEDLESMVIDESAEPKALPLSLLDEITCGFSEKQEIGRGGFAVVYEGS--LLNVT 483 +I + V + +S E AE L E T E+ +G+G + VVY G V Sbjct: 338 LIQAWVTNPDSTAPAEEAEGAGEMLEFDYEYT-ETGERLVLGKGTYGVVYAGRDRHTRVR 396 Query: 484 VAVKKLTNLHMRDAPEVEYNREVECLMRVKHKNIVRFLG 600 +A+K++ R + + + E+ R++HKNIVR+LG Sbjct: 397 IAIKEIPERDSRFSQPL--HEEIALHRRLRHKNIVRYLG 433
>KYK1_DICDI (P18160) Non-receptor tyrosine kinase spore lysis A (EC 2.7.10.2)| (Tyrosine-protein kinase 1) Length = 1584 Score = 36.6 bits (83), Expect = 0.060 Identities = 21/62 (33%), Positives = 31/62 (50%), Gaps = 1/62 (1%) Frame = +1 Query: 424 QEIGRGGFAVVYEGSLLNVTVAVKKLTNLHMRDAPE-VEYNREVECLMRVKHKNIVRFLG 600 Q IG+G F V G VA+K + + V + EV L +++H N+V+FLG Sbjct: 1293 QTIGKGFFGEVKRGYWRETDVAIKIIYRDQFKTKSSLVMFQNEVGILSKLRHPNVVQFLG 1352 Query: 601 YC 606 C Sbjct: 1353 AC 1354
>E2AK3_HUMAN (Q9NZJ5) Eukaryotic translation initiation factor 2-alpha kinase 3| precursor (EC 2.7.11.1) (PRKR-like endoplasmic reticulum kinase) (Pancreatic eIF2-alpha kinase) (HsPEK) Length = 1115 Score = 36.6 bits (83), Expect = 0.060 Identities = 22/63 (34%), Positives = 36/63 (57%), Gaps = 2/63 (3%) Frame = +1 Query: 412 FSEKQEIGRGGFAVVYE--GSLLNVTVAVKKLTNLHMRDAPEVEYNREVECLMRVKHKNI 585 F Q +GRGGF VV+E + + A+K++ L R+ + REV+ L +++H I Sbjct: 592 FEPIQCLGRGGFGVVFEAKNKVDDCNYAIKRI-RLPNRELAREKVMREVKALAKLEHPGI 650 Query: 586 VRF 594 VR+ Sbjct: 651 VRY 653
>M3K2_ARATH (Q9FZ36) Mitogen-activated protein kinase kinase kinase 2 (EC| 2.7.11.25) (Arabidospsis NPK1-related protein kinase 2) Length = 651 Score = 36.6 bits (83), Expect = 0.060 Identities = 25/72 (34%), Positives = 33/72 (45%), Gaps = 13/72 (18%) Frame = +1 Query: 424 QEIGRGGFAVVYEGS-------------LLNVTVAVKKLTNLHMRDAPEVEYNREVECLM 564 Q IGRG F VY G L+ A K+ T H+++ E EV+ L Sbjct: 72 QLIGRGAFGTVYMGMNLDSGELLAVKQVLITSNCASKEKTQAHIQELEE-----EVKLLK 126 Query: 565 RVKHKNIVRFLG 600 + H NIVR+LG Sbjct: 127 NLSHPNIVRYLG 138
>ROS_HUMAN (P08922) Proto-oncogene tyrosine-protein kinase ROS precursor (EC| 2.7.10.1) (c-ros-1) Length = 2347 Score = 36.6 bits (83), Expect = 0.060 Identities = 21/67 (31%), Positives = 34/67 (50%), Gaps = 8/67 (11%) Frame = +1 Query: 430 IGRGGFAVVYEGSLLNVT--------VAVKKLTNLHMRDAPEVEYNREVECLMRVKHKNI 585 +G G F VYEG+ +++ VAVK L D ++E+ +E + + H NI Sbjct: 1951 LGSGAFGEVYEGTAVDILGVGSGEIKVAVKTLKK-GSTDQEKIEFLKEAHLMSKFNHPNI 2009 Query: 586 VRFLGYC 606 ++ LG C Sbjct: 2010 LKQLGVC 2016
>E2AK2_SCHPO (Q9UTE5) Eukaryotic translation initiation factor 2-alpha kinase 2| (EC 2.7.11.1) (Heme-regulated eukaryotic initiation factor eIF-2-alpha kinase) (Heme-regulated inhibitor 2) Length = 639 Score = 36.6 bits (83), Expect = 0.060 Identities = 20/63 (31%), Positives = 33/63 (52%), Gaps = 2/63 (3%) Frame = +1 Query: 412 FSEKQEIGRGGFAVVYE--GSLLNVTVAVKKLTNLHMRDAPEVEYNREVECLMRVKHKNI 585 F E +GRGGF VY + A+KK+ N + + RE++CL ++ H N+ Sbjct: 171 FEEYSLLGRGGFGSVYHVRNKIDGAEYAMKKI-NSTFQQMSYSKIFREIKCLAKMDHPNV 229 Query: 586 VRF 594 +R+ Sbjct: 230 IRY 232
>ATG1_YEAST (P53104) Serine/threonine-protein kinase ATG1 (EC 2.7.11.1)| (Autophagy-related protein 1) (Autophagy protein 3) (Cytoplasm to vacuole targeting protein 10) Length = 897 Score = 36.6 bits (83), Expect = 0.060 Identities = 22/64 (34%), Positives = 40/64 (62%), Gaps = 5/64 (7%) Frame = +1 Query: 412 FSEKQEIGRGGFAVVYEGSLL---NVTVAVKKLTNLHMRDAPEVEYNREVE--CLMRVKH 576 ++ ++EIG+G FA VY G L + VA+K+++ +++ +E N E+E L ++KH Sbjct: 24 YTAEKEIGKGSFATVYRGHLTSDKSQHVAIKEVSRAKLKNKKLLE-NLEIEIAILKKIKH 82 Query: 577 KNIV 588 +IV Sbjct: 83 PHIV 86
>CDK2_ENTHI (Q04770) Cell division protein kinase 2 homolog (EC 2.7.11.22)| Length = 291 Score = 36.6 bits (83), Expect = 0.060 Identities = 20/61 (32%), Positives = 34/61 (55%), Gaps = 2/61 (3%) Frame = +1 Query: 412 FSEKQEIGRGGFAVVYEG--SLLNVTVAVKKLTNLHMRDAPEVEYNREVECLMRVKHKNI 585 + +KQ++G G + VV + ++ N VA+KK+ D V RE+ L+ +KH N+ Sbjct: 4 YEKKQQLGEGTYGVVCKAWDTVCNRYVALKKIKQEREDDGIPVTSVREIAVLLELKHPNV 63 Query: 586 V 588 V Sbjct: 64 V 64
>CDK3_HUMAN (Q00526) Cell division protein kinase 3 (EC 2.7.11.22)| Length = 305 Score = 36.6 bits (83), Expect = 0.060 Identities = 24/65 (36%), Positives = 34/65 (52%), Gaps = 3/65 (4%) Frame = +1 Query: 412 FSEKQEIGRGGFAVVYEGSLLNV--TVAVKKLT-NLHMRDAPEVEYNREVECLMRVKHKN 582 F + ++IG G + VVY+ VA+KK+ +L M P RE+ L +KH N Sbjct: 4 FQKVEKIGEGTYGVVYKAKNRETGQLVALKKIRLDLEMEGVPSTAI-REISLLKELKHPN 62 Query: 583 IVRFL 597 IVR L Sbjct: 63 IVRLL 67
>M3K1_ARATH (O22040) Mitogen-activated protein kinase kinase kinase 1 (EC| 2.7.11.25) (Arabidospsis NPK1-related protein kinase 1) Length = 666 Score = 36.6 bits (83), Expect = 0.060 Identities = 25/72 (34%), Positives = 33/72 (45%), Gaps = 13/72 (18%) Frame = +1 Query: 424 QEIGRGGFAVVYEGS-------------LLNVTVAVKKLTNLHMRDAPEVEYNREVECLM 564 Q IGRG F VY G L+ A K+ T H+++ E EV+ L Sbjct: 73 QLIGRGAFGTVYMGMNLDSGELLAVKQVLIAANFASKEKTQAHIQELEE-----EVKLLK 127 Query: 565 RVKHKNIVRFLG 600 + H NIVR+LG Sbjct: 128 NLSHPNIVRYLG 139
>ULK1_HUMAN (O75385) Serine/threonine-protein kinase ULK1 (EC 2.7.11.1)| (Unc-51-like kinase 1) Length = 1050 Score = 36.2 bits (82), Expect = 0.078 Identities = 22/62 (35%), Positives = 36/62 (58%), Gaps = 3/62 (4%) Frame = +1 Query: 412 FSEKQEIGRGGFAVVYEG---SLLNVTVAVKKLTNLHMRDAPEVEYNREVECLMRVKHKN 582 FS K IG G FAVV++G ++ VAVK + ++ + + +E++ L +KH+N Sbjct: 16 FSRKDLIGHGAFAVVFKGRHREKHDLEVAVKCINKKNLAKS-QTLLGKEIKILKELKHEN 74 Query: 583 IV 588 IV Sbjct: 75 IV 76
>MYLK_DICDI (P25323) Myosin light chain kinase (EC 2.7.11.18) (MLCK)| Length = 295 Score = 36.2 bits (82), Expect = 0.078 Identities = 20/68 (29%), Positives = 33/68 (48%), Gaps = 2/68 (2%) Frame = +1 Query: 391 LDEITCGFSEKQEIGRGGFAVVY--EGSLLNVTVAVKKLTNLHMRDAPEVEYNREVECLM 564 + E+ + K+E+GRG F++VY E A+K + + E EV+ L Sbjct: 1 MTEVEKIYEFKEELGRGAFSIVYLGENKQTKQRYAIKVINKSELGKDYEKNLKMEVDILK 60 Query: 565 RVKHKNIV 588 +V H NI+ Sbjct: 61 KVNHPNII 68
>ULK1_MOUSE (O70405) Serine/threonine-protein kinase ULK1 (EC 2.7.11.1)| (Unc-51-like kinase 1) (Serine/threonine-protein kinase Unc51.1) Length = 1051 Score = 36.2 bits (82), Expect = 0.078 Identities = 22/62 (35%), Positives = 36/62 (58%), Gaps = 3/62 (4%) Frame = +1 Query: 412 FSEKQEIGRGGFAVVYEG---SLLNVTVAVKKLTNLHMRDAPEVEYNREVECLMRVKHKN 582 FS K IG G FAVV++G ++ VAVK + ++ + + +E++ L +KH+N Sbjct: 16 FSRKDLIGHGAFAVVFKGRHREKHDLEVAVKCINKKNLAKS-QTLLGKEIKILKELKHEN 74 Query: 583 IV 588 IV Sbjct: 75 IV 76
>PR2_DROME (Q9I7F7) Tyrosine-protein kinase PR2 (EC 2.7.10.2)| Length = 1337 Score = 36.2 bits (82), Expect = 0.078 Identities = 21/66 (31%), Positives = 36/66 (54%), Gaps = 4/66 (6%) Frame = +1 Query: 415 SEKQEIGRGGFAVVYEGSLLN----VTVAVKKLTNLHMRDAPEVEYNREVECLMRVKHKN 582 S +++G G F +V +G N + VA+K L M+ P +E+ +E + ++H+N Sbjct: 134 SVNKQLGTGEFGIVQQGVWSNGNERIQVAIKCLCRERMQSNP-MEFLKEAAIMHSIEHEN 192 Query: 583 IVRFLG 600 IVR G Sbjct: 193 IVRLYG 198
>BRAF1_CHICK (Q04982) B-Raf proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (Rmil serine/threonine-protein kinase) (c-Rmil) Length = 806 Score = 36.2 bits (82), Expect = 0.078 Identities = 25/69 (36%), Positives = 33/69 (47%) Frame = +1 Query: 397 EITCGFSEKQEIGRGGFAVVYEGSLLNVTVAVKKLTNLHMRDAPEVEYNREVECLMRVKH 576 +IT G Q IG G F VY+G + VAVK L + EV L + +H Sbjct: 496 QITVG----QRIGSGSFGTVYKGKW-HGDVAVKMLNVTAPTPQQLQAFKNEVGVLRKTRH 550 Query: 577 KNIVRFLGY 603 NI+ F+GY Sbjct: 551 VNILLFMGY 559
>BRAF1_HUMAN (P15056) B-Raf proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (p94) (v-Raf murine sarcoma viral oncogene homolog B1) Length = 766 Score = 36.2 bits (82), Expect = 0.078 Identities = 25/69 (36%), Positives = 33/69 (47%) Frame = +1 Query: 397 EITCGFSEKQEIGRGGFAVVYEGSLLNVTVAVKKLTNLHMRDAPEVEYNREVECLMRVKH 576 +IT G Q IG G F VY+G + VAVK L + EV L + +H Sbjct: 456 QITVG----QRIGSGSFGTVYKGKW-HGDVAVKMLNVTAPTPQQLQAFKNEVGVLRKTRH 510 Query: 577 KNIVRFLGY 603 NI+ F+GY Sbjct: 511 VNILLFMGY 519
>STY1_SCHPO (Q09892) Mitogen-activated protein kinase sty1 (EC 2.7.11.24) (MAP| kinase sty1) (MAP kinase spc1) Length = 349 Score = 36.2 bits (82), Expect = 0.078 Identities = 22/66 (33%), Positives = 34/66 (51%), Gaps = 2/66 (3%) Frame = +1 Query: 397 EITCGFSEKQEIGRGGFAVV--YEGSLLNVTVAVKKLTNLHMRDAPEVEYNREVECLMRV 570 EIT +S+ Q IG G F +V + L + VAVKK+ RE++ L + Sbjct: 15 EITTRYSDLQPIGMGAFGLVCSAKDQLTGMNVAVKKIMKPFSTPVLAKRTYRELKLLKHL 74 Query: 571 KHKNIV 588 +H+NI+ Sbjct: 75 RHENII 80
>RMIL_AVEVR (P27966) Serine/threonine-protein kinase transforming protein Rmil| (EC 2.7.11.1) Length = 450 Score = 36.2 bits (82), Expect = 0.078 Identities = 25/69 (36%), Positives = 33/69 (47%) Frame = +1 Query: 397 EITCGFSEKQEIGRGGFAVVYEGSLLNVTVAVKKLTNLHMRDAPEVEYNREVECLMRVKH 576 +IT G Q IG G F VY+G + VAVK L + EV L + +H Sbjct: 82 QITVG----QRIGSGSFGTVYKGKW-HGDVAVKMLNVTAPTPQQLQAFKNEVGVLRKTRH 136 Query: 577 KNIVRFLGY 603 NI+ F+GY Sbjct: 137 VNILLFMGY 145
>PCTK1_RAT (Q63686) Serine/threonine-protein kinase PCTAIRE-1 (EC 2.7.11.22)| (PCTAIRE-motif protein kinase 1) Length = 496 Score = 36.2 bits (82), Expect = 0.078 Identities = 35/107 (32%), Positives = 53/107 (49%), Gaps = 8/107 (7%) Frame = +1 Query: 292 LQMDIQMIPSTVEDL--ESMVIDESAEPKALPLSLLDEITCG----FSEKQEIGRGGFAV 453 L DI++ +E L S + D+ + P+SL EI G + + ++G G +A Sbjct: 120 LPADIRLPEGYLEKLTLNSPIGDKPLSRRLRPVSL-SEIGFGKLETYIKLDKLGEGTYAT 178 Query: 454 VYEGS--LLNVTVAVKKLTNLHMRDAPEVEYNREVECLMRVKHKNIV 588 VY+G L + VA+K++ H AP REV L +KH NIV Sbjct: 179 VYKGKSKLTDNLVALKEIRLEHEEGAPCTAI-REVSLLKDLKHANIV 224
>FPS_AVISP (P00541) Tyrosine-protein kinase transforming protein Fps (EC| 2.7.10.2) Length = 533 Score = 36.2 bits (82), Expect = 0.078 Identities = 22/63 (34%), Positives = 31/63 (49%), Gaps = 2/63 (3%) Frame = +1 Query: 424 QEIGRGGFAVVYEGSLL--NVTVAVKKLTNLHMRDAPEVEYNREVECLMRVKHKNIVRFL 597 + IGRG F V+ G L N VAVK + + ++ +E L + H NIVR + Sbjct: 276 ERIGRGNFGEVFSGRLRADNTPVAVKSCRET-LPPELKAKFLQEARILKQYNHPNIVRLI 334 Query: 598 GYC 606 G C Sbjct: 335 GVC 337
>CDC22_ORYSA (P29619) Cell division control protein 2 homolog 2 (EC 2.7.11.22)| Length = 292 Score = 36.2 bits (82), Expect = 0.078 Identities = 20/62 (32%), Positives = 34/62 (54%), Gaps = 2/62 (3%) Frame = +1 Query: 412 FSEKQEIGRGGFAVVYEGSL--LNVTVAVKKLTNLHMRDAPEVEYNREVECLMRVKHKNI 585 + + ++IG G + VVY+G N T+A+KK+ + RE+ L ++H+NI Sbjct: 4 YEKVEKIGEGTYGVVYKGKHRHTNETIALKKIRLEQEDEGVPSTAIREISLLKEMQHRNI 63 Query: 586 VR 591 VR Sbjct: 64 VR 65
>ATG1_CRYNE (Q5K8D3) Serine/threonine-protein kinase ATG1 (EC 2.7.11.1)| (Autophagy-related protein 1) Length = 988 Score = 36.2 bits (82), Expect = 0.078 Identities = 20/56 (35%), Positives = 29/56 (51%), Gaps = 2/56 (3%) Frame = +1 Query: 427 EIGRGGFAVVYEG--SLLNVTVAVKKLTNLHMRDAPEVEYNREVECLMRVKHKNIV 588 EIGRG FA VY+G S V +A+K ++ + E+ L + H+NIV Sbjct: 32 EIGRGSFATVYKGYRSKTRVPIAIKAVSRQKLTSKLLENLESEINILKVINHRNIV 87
>FPS_FUJSV (P00530) Tyrosine-protein kinase transforming protein FPS (EC| 2.7.10.2) Length = 873 Score = 36.2 bits (82), Expect = 0.078 Identities = 22/63 (34%), Positives = 31/63 (49%), Gaps = 2/63 (3%) Frame = +1 Query: 424 QEIGRGGFAVVYEGSLL--NVTVAVKKLTNLHMRDAPEVEYNREVECLMRVKHKNIVRFL 597 + IGRG F V+ G L N VAVK + + ++ +E L + H NIVR + Sbjct: 616 ERIGRGNFGEVFSGRLRADNTPVAVKSCRET-LPPELKAKFLQEARILKQCNHPNIVRLI 674 Query: 598 GYC 606 G C Sbjct: 675 GVC 677
>BRAF1_MOUSE (P28028) B-Raf proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (Fragment) Length = 328 Score = 36.2 bits (82), Expect = 0.078 Identities = 25/69 (36%), Positives = 33/69 (47%) Frame = +1 Query: 397 EITCGFSEKQEIGRGGFAVVYEGSLLNVTVAVKKLTNLHMRDAPEVEYNREVECLMRVKH 576 +IT G Q IG G F VY+G + VAVK L + EV L + +H Sbjct: 18 QITVG----QRIGSGSFGTVYKGKW-HGDVAVKMLNVTAPTPQQLQAFKNEVGVLRKTRH 72 Query: 577 KNIVRFLGY 603 NI+ F+GY Sbjct: 73 VNILLFMGY 81
>BRAF1_COTJA (P34908) B-Raf proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (RMIL serine/threonine-protein kinase) (c-RMIL) Length = 807 Score = 36.2 bits (82), Expect = 0.078 Identities = 25/69 (36%), Positives = 33/69 (47%) Frame = +1 Query: 397 EITCGFSEKQEIGRGGFAVVYEGSLLNVTVAVKKLTNLHMRDAPEVEYNREVECLMRVKH 576 +IT G Q IG G F VY+G + VAVK L + EV L + +H Sbjct: 496 QITVG----QRIGSGSFGTVYKGKW-HGDVAVKMLNVTAPTPQQLQAFKNEVGVLRKTRH 550 Query: 577 KNIVRFLGY 603 NI+ F+GY Sbjct: 551 VNILLFMGY 559
>RPK1_IPONI (P93194) Receptor-like protein kinase precursor (EC 2.7.11.1)| Length = 1109 Score = 36.2 bits (82), Expect = 0.078 Identities = 21/66 (31%), Positives = 38/66 (57%), Gaps = 1/66 (1%) Frame = +1 Query: 397 EITCGFSEKQEIGRGGFAVVYEGSLLNVTV-AVKKLTNLHMRDAPEVEYNREVECLMRVK 573 E T ++K IG+G +Y+ +L V AVKKL +++ V RE+E + +V+ Sbjct: 811 EATENLNDKYVIGKGAHGTIYKATLSPDKVYAVKKLVFTGIKNG-SVSMVREIETIGKVR 869 Query: 574 HKNIVR 591 H+N+++ Sbjct: 870 HRNLIK 875
>RMIL_AVII1 (P10533) Serine/threonine-protein kinase transforming protein Rmil| (EC 2.7.11.1) Length = 367 Score = 36.2 bits (82), Expect = 0.078 Identities = 25/69 (36%), Positives = 33/69 (47%) Frame = +1 Query: 397 EITCGFSEKQEIGRGGFAVVYEGSLLNVTVAVKKLTNLHMRDAPEVEYNREVECLMRVKH 576 +IT G Q IG G F VY+G + VAVK L + EV L + +H Sbjct: 66 QITVG----QRIGSGSFGTVYKGKW-HGDVAVKMLNVTAPTPQQLQAFKNEVGVLRKTRH 120 Query: 577 KNIVRFLGY 603 NI+ F+GY Sbjct: 121 VNILLFMGY 129
>CDC15_YEAST (P27636) Cell division control protein 15 (EC 2.7.11.1)| Length = 974 Score = 35.8 bits (81), Expect = 0.10 Identities = 22/77 (28%), Positives = 39/77 (50%), Gaps = 2/77 (2%) Frame = +1 Query: 379 PLSLLDEITCGFSEKQEIGRGGFAVVYE--GSLLNVTVAVKKLTNLHMRDAPEVEYNREV 552 P+ E + + KQ IGRG + VVY+ + VA+K++ ++ D + E+ Sbjct: 14 PIQRASEKSVQYHLKQVIGRGSYGVVYKAINKHTDQVVAIKEV--VYENDEELNDIMAEI 71 Query: 553 ECLMRVKHKNIVRFLGY 603 L + H NIV++ G+ Sbjct: 72 SLLKNLNHNNIVKYHGF 88
>M3K7_MOUSE (Q62073) Mitogen-activated protein kinase kinase kinase 7 (EC| 2.7.11.25) (Transforming growth factor-beta-activated kinase 1) (TGF-beta-activated kinase 1) Length = 579 Score = 35.8 bits (81), Expect = 0.10 Identities = 29/99 (29%), Positives = 44/99 (44%), Gaps = 3/99 (3%) Frame = +1 Query: 319 STVEDLESMVIDESAEPKALPLSLLDEITCGFSE---KQEIGRGGFAVVYEGSLLNVTVA 489 ST S ++E P +L+ + E ++ +GRG F VV + VA Sbjct: 2 STASAASSSSSSSASEMIEAPSQVLNFEEIDYKEIEVEEVVGRGAFGVVCKAKWRAKDVA 61 Query: 490 VKKLTNLHMRDAPEVEYNREVECLMRVKHKNIVRFLGYC 606 +K++ + R A VE + L RV H NIV+ G C Sbjct: 62 IKQIESESERKAFIVELRQ----LSRVNHPNIVKLYGAC 96
>PKNK_MYCTU (P95078) Probable serine/threonine-protein kinase pknK (EC| 2.7.11.1) Length = 1110 Score = 35.8 bits (81), Expect = 0.10 Identities = 31/77 (40%), Positives = 40/77 (51%), Gaps = 3/77 (3%) Frame = +1 Query: 376 LPLSLLDEITCGFSEKQEIGRGGFAVVYE--GSLLNVTVAVKKLTNLHMRDAPEVEYNRE 549 +P LL+ GF +EIGRGGF VVY L+ VAVK L+ RD E + RE Sbjct: 17 IPAELLE---AGFDNVEEIGRGGFGVVYRCVQPSLDRAVAVKVLSTDLDRDNLE-RFLRE 72 Query: 550 VECLMRVK-HKNIVRFL 597 + R+ H +IV L Sbjct: 73 QRAMGRLSGHPHIVTVL 89
>PKNK_MYCBO (Q7TXA9) Probable serine/threonine-protein kinase pknK (EC| 2.7.11.1) Length = 1110 Score = 35.8 bits (81), Expect = 0.10 Identities = 31/77 (40%), Positives = 40/77 (51%), Gaps = 3/77 (3%) Frame = +1 Query: 376 LPLSLLDEITCGFSEKQEIGRGGFAVVYE--GSLLNVTVAVKKLTNLHMRDAPEVEYNRE 549 +P LL+ GF +EIGRGGF VVY L+ VAVK L+ RD E + RE Sbjct: 17 IPAELLE---AGFDNVEEIGRGGFGVVYRCVQPSLDRAVAVKVLSTDLDRDNLE-RFLRE 72 Query: 550 VECLMRVK-HKNIVRFL 597 + R+ H +IV L Sbjct: 73 QRAMGRLSGHPHIVTVL 89
>ATG1_DEBHA (Q6BS08) Serine/threonine-protein kinase ATG1 (EC 2.7.11.1)| (Autophagy-related protein 1) Length = 875 Score = 35.8 bits (81), Expect = 0.10 Identities = 23/67 (34%), Positives = 35/67 (52%), Gaps = 3/67 (4%) Frame = +1 Query: 412 FSEKQEIGRGGFAVVYE--GSLLNVTVAVKKLTNLHMRDAPEVE-YNREVECLMRVKHKN 582 +S EIG+G FA VY+ + N +VA+K + ++ VE E+ L +KH + Sbjct: 22 YSIGPEIGKGSFATVYKCFNTKTNESVAIKSVVRSKLKSKKLVENLEIEISILKTMKHPH 81 Query: 583 IVRFLGY 603 IV L Y Sbjct: 82 IVGLLDY 88
>TAOK1_RAT (O88664) Serine/threonine-protein kinase TAO1 (EC 2.7.11.1)| (Thousand and one amino acid protein 1) Length = 1001 Score = 35.8 bits (81), Expect = 0.10 Identities = 21/66 (31%), Positives = 35/66 (53%), Gaps = 3/66 (4%) Frame = +1 Query: 412 FSEKQEIGRGGFAVVY--EGSLLNVTVAVKKLTNLHMRDAPE-VEYNREVECLMRVKHKN 582 F++ +EIG G F VY N VA+KK++ + + + +EV+ L R+KH N Sbjct: 28 FTDLREIGHGSFGAVYFARDVRTNEVVAIKKMSYSGKQSTEKWQDIIKEVKFLQRIKHPN 87 Query: 583 IVRFLG 600 + + G Sbjct: 88 SIEYKG 93
>TAOK1_MOUSE (Q5F2E8) Serine/threonine-protein kinase TAO1 (EC 2.7.11.1)| (Thousand and one amino acid protein 1) Length = 1001 Score = 35.8 bits (81), Expect = 0.10 Identities = 21/66 (31%), Positives = 35/66 (53%), Gaps = 3/66 (4%) Frame = +1 Query: 412 FSEKQEIGRGGFAVVY--EGSLLNVTVAVKKLTNLHMRDAPE-VEYNREVECLMRVKHKN 582 F++ +EIG G F VY N VA+KK++ + + + +EV+ L R+KH N Sbjct: 28 FTDLREIGHGSFGAVYFARDVRTNEVVAIKKMSYSGKQSTEKWQDIIKEVKFLQRIKHPN 87 Query: 583 IVRFLG 600 + + G Sbjct: 88 SIEYKG 93
>TAOK1_HUMAN (Q7L7X3) Serine/threonine-protein kinase TAO1 (EC 2.7.11.1)| (Thousand and one amino acid protein 1) (STE20-like kinase PSK2) (Kinase from chicken homolog B) (hKFC-B) Length = 1001 Score = 35.8 bits (81), Expect = 0.10 Identities = 21/66 (31%), Positives = 35/66 (53%), Gaps = 3/66 (4%) Frame = +1 Query: 412 FSEKQEIGRGGFAVVY--EGSLLNVTVAVKKLTNLHMRDAPE-VEYNREVECLMRVKHKN 582 F++ +EIG G F VY N VA+KK++ + + + +EV+ L R+KH N Sbjct: 28 FTDLREIGHGSFGAVYFARDVRTNEVVAIKKMSYSGKQSTEKWQDIIKEVKFLQRIKHPN 87 Query: 583 IVRFLG 600 + + G Sbjct: 88 SIEYKG 93
>MPK1_ARATH (Q39021) Mitogen-activated protein kinase homolog 1 (EC 2.7.11.24)| (MAP kinase 1) (AtMPK1) Length = 370 Score = 35.4 bits (80), Expect = 0.13 Identities = 21/68 (30%), Positives = 36/68 (52%), Gaps = 2/68 (2%) Frame = +1 Query: 391 LDEITCGFSEKQEIGRGGFAVVYEG--SLLNVTVAVKKLTNLHMRDAPEVEYNREVECLM 564 L EI + + IGRG + VV S N VA+KK+ N++ + RE++ L Sbjct: 25 LFEIDTKYMPIKPIGRGAYGVVCSSVNSDTNEKVAIKKIHNVYENRIDALRTLRELKLLR 84 Query: 565 RVKHKNIV 588 ++H+N++ Sbjct: 85 HLRHENVI 92
>M3K7_HUMAN (O43318) Mitogen-activated protein kinase kinase kinase 7 (EC| 2.7.11.25) (Transforming growth factor-beta-activated kinase 1) (TGF-beta-activated kinase 1) Length = 606 Score = 35.4 bits (80), Expect = 0.13 Identities = 22/62 (35%), Positives = 32/62 (51%) Frame = +1 Query: 421 KQEIGRGGFAVVYEGSLLNVTVAVKKLTNLHMRDAPEVEYNREVECLMRVKHKNIVRFLG 600 ++ +GRG F VV + VA+K++ + R A VE + L RV H NIV+ G Sbjct: 39 EEVVGRGAFGVVCKAKWRAKDVAIKQIESESERKAFIVELRQ----LSRVNHPNIVKLYG 94 Query: 601 YC 606 C Sbjct: 95 AC 96
>LTK_MOUSE (P08923) Leukocyte tyrosine kinase receptor precursor (EC 2.7.10.1)| Length = 888 Score = 35.4 bits (80), Expect = 0.13 Identities = 25/87 (28%), Positives = 40/87 (45%), Gaps = 7/87 (8%) Frame = +1 Query: 361 AEPKALPLSLLDEITCGFSEKQEIGRGGFAVVYEGSLLN-------VTVAVKKLTNLHMR 519 A+P LP L + + + +G G F VYEG + + VA+K L L Sbjct: 489 AQPWPLPPGLTEVSPANVTLLRALGHGAFGEVYEGLVTGLPGDSSPLPVAIKTLPEL-CS 547 Query: 520 DAPEVEYNREVECLMRVKHKNIVRFLG 600 E+++ E + + H+NIVR +G Sbjct: 548 HQDELDFLMEALIISKFSHQNIVRCVG 574
>CDC7_SCHPO (P41892) Cell division control protein 7 (EC 2.7.11.1)| Length = 1062 Score = 35.4 bits (80), Expect = 0.13 Identities = 22/61 (36%), Positives = 32/61 (52%), Gaps = 4/61 (6%) Frame = +1 Query: 430 IGRGGFAVVYEGSLLNV----TVAVKKLTNLHMRDAPEVEYNREVECLMRVKHKNIVRFL 597 +G+G F VY G LN+ TVAVKK+ M + E++ L + H NIV++ Sbjct: 15 LGKGAFGAVYRG--LNIKNGETVAVKKVKLSKMLKSDLSVIKMEIDLLKNLDHPNIVKYR 72 Query: 598 G 600 G Sbjct: 73 G 73
>ABDA_DROME (P29555) Homeobox protein abdominal-A| Length = 590 Score = 35.4 bits (80), Expect = 0.13 Identities = 20/46 (43%), Positives = 27/46 (58%) Frame = -3 Query: 610 QHNIQEIALYFCASPSSSIQPLGCTPPQAHHAYAGWSTSSPPPSHS 473 QH+I ++A AS + Q L TPP A ++ AG S+ SP PS S Sbjct: 165 QHHISKLAAAAVASHGHAHQQLLLTPPSAGNSQAGDSSCSPSPSAS 210
>KIC1_YEAST (P38692) Serine/threonine-protein kinase KIC1 (EC 2.7.11.1) (Kinase| that interacts with CDC31) (N-rich kinase 1) Length = 1080 Score = 35.4 bits (80), Expect = 0.13 Identities = 29/77 (37%), Positives = 42/77 (54%), Gaps = 4/77 (5%) Frame = +1 Query: 397 EITCGFSEKQEIGRGGFAVVYEG-SLLNVTVAVKKLTNLHMRDAPEVE-YNREVECLMRV 570 +++ F + IGRG F VVY+G ++ V K+ NL D+ EVE RE++ L + Sbjct: 18 DVSSLFKRTEVIGRGKFGVVYKGYNVKTGRVYAIKVLNLD-SDSDEVEDVQREIQFLASL 76 Query: 571 KH-KNIVRFLG-YCADT 615 K NI R+ G Y DT Sbjct: 77 KQISNITRYYGSYLKDT 93
>CC2H1_TRYBB (P38973) Cell division control protein 2 homolog 1 (EC 2.7.11.22)| Length = 301 Score = 35.4 bits (80), Expect = 0.13 Identities = 20/67 (29%), Positives = 31/67 (46%), Gaps = 2/67 (2%) Frame = +1 Query: 412 FSEKQEIGRGGFAVVYEGS--LLNVTVAVKKLTNLHMRDAPEVEYNREVECLMRVKHKNI 585 + Q+IG G + VV+ VAVK++ + RE+ L ++H+NI Sbjct: 5 YERLQKIGEGSYGVVFRARDVTTGTIVAVKRIRLEKEEEGVPCTAIREISILKELRHENI 64 Query: 586 VRFLGYC 606 VR L C Sbjct: 65 VRLLDVC 71
>ROS_AVISU (P00529) Tyrosine-protein kinase transforming protein ros (EC| 2.7.10.1) Length = 402 Score = 35.4 bits (80), Expect = 0.13 Identities = 26/94 (27%), Positives = 44/94 (46%), Gaps = 8/94 (8%) Frame = +1 Query: 349 IDESAEPKALPLSLLDEITCGFSEKQEIGRGGFAVVYEGSLLNV--------TVAVKKLT 504 + AE ++LP D++ + +G G F VYEG+ L++ VAVK L Sbjct: 81 LPSQAEIESLPAFPRDKLNL----HKLLGSGAFGEVYEGTALDILADGSGESRVAVKTLK 136 Query: 505 NLHMRDAPEVEYNREVECLMRVKHKNIVRFLGYC 606 D + E+ +E + + H +I++ LG C Sbjct: 137 R-GATDQEKSEFLKEAHLMSKFDHPHILKLLGVC 169
>E2AK3_DROME (Q9NIV1) Eukaryotic translation initiation factor 2-alpha kinase| precursor (EC 2.7.11.1) (PRKR-like endoplasmic reticulum kinase) (PERK) (PEK) (DmPEK) Length = 1162 Score = 35.4 bits (80), Expect = 0.13 Identities = 24/70 (34%), Positives = 35/70 (50%), Gaps = 2/70 (2%) Frame = +1 Query: 412 FSEKQEIGRGGFAVVYE--GSLLNVTVAVKKLTNLHMRDAPEVEYNREVECLMRVKHKNI 585 F Q +GRGGF VV+E L A+K++T L +++ RE L +H NI Sbjct: 642 FELMQCLGRGGFGVVFEAKNKLDENRYAIKRIT-LPNKESSRQRVLREARTLASCEHHNI 700 Query: 586 VRFLGYCADT 615 VR+ +T Sbjct: 701 VRYFHSWTET 710
>7LESS_DROVI (P20806) Protein sevenless (EC 2.7.10.1)| Length = 2594 Score = 35.4 bits (80), Expect = 0.13 Identities = 21/65 (32%), Positives = 31/65 (47%), Gaps = 3/65 (4%) Frame = +1 Query: 430 IGRGGFAVVYEGSLLNVTVAVKK---LTNLHMRDAPEVEYNREVECLMRVKHKNIVRFLG 600 +G G F VYEG L A + + +L + E +E + + KH+NIV +G Sbjct: 2230 LGSGAFGEVYEGQLQAEDEAQPQRVAIKSLRKGASEFAELLQEAQLMSNFKHENIVCLIG 2289 Query: 601 YCADT 615 C DT Sbjct: 2290 ICCDT 2294
>ROS_CHICK (P08941) Proto-oncogene tyrosine-protein kinase ROS precursor (EC| 2.7.10.1) (c-ros-1) Length = 2311 Score = 35.4 bits (80), Expect = 0.13 Identities = 26/94 (27%), Positives = 44/94 (46%), Gaps = 8/94 (8%) Frame = +1 Query: 349 IDESAEPKALPLSLLDEITCGFSEKQEIGRGGFAVVYEGSLLNV--------TVAVKKLT 504 + AE ++LP D++ + +G G F VYEG+ L++ VAVK L Sbjct: 1944 LPSQAEIESLPAFPRDKLNL----HKLLGSGAFGEVYEGTALDILADGSGESRVAVKTLK 1999 Query: 505 NLHMRDAPEVEYNREVECLMRVKHKNIVRFLGYC 606 D + E+ +E + + H +I++ LG C Sbjct: 2000 R-GATDQEKSEFLKEAHLMSKFDHPHILKLLGVC 2032
>YSK4_HUMAN (Q56UN5) SPS1/STE20-related protein kinase YSK4 (EC 2.7.11.1)| (Regulated in COPD, protein kinase) Length = 1328 Score = 35.4 bits (80), Expect = 0.13 Identities = 26/79 (32%), Positives = 43/79 (54%), Gaps = 5/79 (6%) Frame = +1 Query: 385 SLLDEITCGFSEKQEIGRGGFAVVYEG-SLLNVTVAVKKLT-NLHMRDAPEVEYNR---E 549 SL E +++ + +G+G + VY G + +AVK++ + + A E EY + E Sbjct: 1052 SLKSEEPILWTKGEILGKGAYGTVYCGLTSQGQLIAVKQVALDTSNKLAAEKEYRKLQEE 1111 Query: 550 VECLMRVKHKNIVRFLGYC 606 V+ L +KH NIV +LG C Sbjct: 1112 VDLLKALKHVNIVAYLGTC 1130
>CDC2_VIGAC (Q41639) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34cdc2) Length = 294 Score = 35.0 bits (79), Expect = 0.17 Identities = 19/62 (30%), Positives = 34/62 (54%), Gaps = 2/62 (3%) Frame = +1 Query: 412 FSEKQEIGRGGFAVVYEGS--LLNVTVAVKKLTNLHMRDAPEVEYNREVECLMRVKHKNI 585 + + ++IG G + VVY+ + N T+A+KK+ + RE+ L ++H+NI Sbjct: 4 YEKVEKIGEGTYGVVYKARDRVTNETIALKKIRLEQEDEGVPSTAIREISLLKEMQHRNI 63 Query: 586 VR 591 VR Sbjct: 64 VR 65
>AVR2A_XENLA (P27039) Activin receptor type 2A precursor (EC 2.7.11.30) (Activin| receptor type II) (ACTR-II) Length = 514 Score = 35.0 bits (79), Expect = 0.17 Identities = 21/55 (38%), Positives = 31/55 (56%) Frame = +1 Query: 436 RGGFAVVYEGSLLNVTVAVKKLTNLHMRDAPEVEYNREVECLMRVKHKNIVRFLG 600 RG F V++ LLN TVAVK ++D + E+ L +KH+NI+ F+G Sbjct: 201 RGRFGCVWKAQLLNETVAVKIFP---VQDKLSWQNEYEIYSLPGMKHENILYFIG 252
>CRK1_SCHPO (Q12126) Serine/threonine-protein kinase crk1 (EC 2.7.11.23)| (Mitotic catastrophe suppressor 6) Length = 335 Score = 35.0 bits (79), Expect = 0.17 Identities = 17/64 (26%), Positives = 36/64 (56%), Gaps = 2/64 (3%) Frame = +1 Query: 412 FSEKQEIGRGGFAVVYEGSL--LNVTVAVKKLTNLHMRDAPEVEYNREVECLMRVKHKNI 585 + +++++G G +AVV+ G N VA+KK+ +D ++ RE++ L +H N+ Sbjct: 11 YVKERKVGEGTYAVVFLGRQKETNRRVAIKKIKVGQFKDGIDISALREIKFLRESRHDNV 70 Query: 586 VRFL 597 + + Sbjct: 71 IELV 74
>YL670_MIMIV (Q5UNT4) Putative serine/threonine-protein kinase L670 (EC| 2.7.11.1) Length = 539 Score = 35.0 bits (79), Expect = 0.17 Identities = 24/86 (27%), Positives = 43/86 (50%), Gaps = 10/86 (11%) Frame = +1 Query: 376 LPLSLLDEITCGFSEKQ--------EIGRGGFAVVYEGSLLNVTVAVKKLTNLHMRDAPE 531 +P+ L + +T ++E Q ++G G F +V + N +A+K H D+ E Sbjct: 238 IPIELQNSLTIEYTENQLNNMNVIEKLGIGSFGLVNKVKFDNTEIALK---THHPDDSKE 294 Query: 532 --VEYNREVECLMRVKHKNIVRFLGY 603 VE RE+ ++ + H NI++ GY Sbjct: 295 IIVESLREINNMIMLDHPNIIKMHGY 320
>WNK2_HUMAN (Q9Y3S1) Serine/threonine-protein kinase WNK2 (EC 2.7.11.1)| (Protein kinase with no lysine 2) (Protein kinase, lysine-deficient 2) Length = 2297 Score = 35.0 bits (79), Expect = 0.17 Identities = 23/66 (34%), Positives = 31/66 (46%), Gaps = 7/66 (10%) Frame = +1 Query: 427 EIGRGGFAVVYEGSLLNVTVAV-------KKLTNLHMRDAPEVEYNREVECLMRVKHKNI 585 E+GRG F VY+G V V +KLT L + + E E L ++H NI Sbjct: 200 ELGRGSFKTVYKGLDTETWVEVAWCELQDRKLTKLERQ-----RFKEEAEMLKGLQHPNI 254 Query: 586 VRFLGY 603 VRF + Sbjct: 255 VRFYDF 260
>FPS_DROME (P18106) Tyrosine-protein kinase Fps85D (EC 2.7.10.2) (dFer)| Length = 1325 Score = 35.0 bits (79), Expect = 0.17 Identities = 19/62 (30%), Positives = 32/62 (51%), Gaps = 1/62 (1%) Frame = +1 Query: 424 QEIGRGGFAVVYEGSLLNVTVAVK-KLTNLHMRDAPEVEYNREVECLMRVKHKNIVRFLG 600 + IGRG F VY+ L + + V K + + D + ++ +E L + H NIV+ +G Sbjct: 1067 ERIGRGNFGDVYKAKLKSTKLDVAVKTCRMTLPDEQKRKFLQEGRILKQYDHPNIVKLIG 1126 Query: 601 YC 606 C Sbjct: 1127 IC 1128
>TAO1B_XENLA (Q7ZYJ0) Serine/threonine-protein kinase TAO1-B (EC 2.7.11.1)| (Thousand and one amino acid protein 1-B) Length = 1001 Score = 35.0 bits (79), Expect = 0.17 Identities = 23/82 (28%), Positives = 41/82 (50%), Gaps = 3/82 (3%) Frame = +1 Query: 364 EPKALPLSLLDEITCGFSEKQEIGRGGFAVVY--EGSLLNVTVAVKKLTNLHMRDAPE-V 534 +P L D+ FS+ +EIG G F VY + + VA+KK++ + + Sbjct: 12 DPDVAELFFRDDPEKLFSDLREIGHGSFGAVYFAHDARTSEVVAIKKMSYSGKQSNEKWQ 71 Query: 535 EYNREVECLMRVKHKNIVRFLG 600 + +EV+ L R++H N + + G Sbjct: 72 DIIKEVKFLQRIQHPNSIEYKG 93
>TAO1A_XENLA (Q6NU21) Serine/threonine-protein kinase TAO1-A (EC 2.7.11.1)| (Thousand and one amino acid protein 1-A) Length = 1001 Score = 35.0 bits (79), Expect = 0.17 Identities = 21/66 (31%), Positives = 35/66 (53%), Gaps = 3/66 (4%) Frame = +1 Query: 412 FSEKQEIGRGGFAVVY--EGSLLNVTVAVKKLTNLHMRDAPE-VEYNREVECLMRVKHKN 582 FS+ +EIG G F VY + VA+KK++ + + + +EV+ L R+KH N Sbjct: 28 FSDLREIGHGSFGAVYFAHDASTREVVAIKKMSYSGKQSNEKWQDIVKEVKFLQRIKHPN 87 Query: 583 IVRFLG 600 + + G Sbjct: 88 SIEYKG 93
>7LESS_DROME (P13368) Protein sevenless (EC 2.7.10.1)| Length = 2554 Score = 35.0 bits (79), Expect = 0.17 Identities = 25/69 (36%), Positives = 33/69 (47%), Gaps = 7/69 (10%) Frame = +1 Query: 430 IGRGGFAVVYEGSLLNVT------VAVKKLTNLHMRDAPE-VEYNREVECLMRVKHKNIV 588 +G G F VYEG L VA+K L + A E E +E + + KH+NIV Sbjct: 2215 LGSGAFGEVYEGQLKTEDSEEPQRVAIKSLR----KGASEFAELLQEAQLMSNFKHENIV 2270 Query: 589 RFLGYCADT 615 +G C DT Sbjct: 2271 CLVGICFDT 2279
>TESK1_RAT (Q63572) Dual specificity testis-specific protein kinase 1 (EC| 2.7.12.1) (Testicular protein kinase 1) Length = 628 Score = 35.0 bits (79), Expect = 0.17 Identities = 24/76 (31%), Positives = 41/76 (53%), Gaps = 1/76 (1%) Frame = +1 Query: 382 LSLLDEITCGFSEKQEIGRGGFAVVYE-GSLLNVTVAVKKLTNLHMRDAPEVEYNREVEC 558 L+ +D+ C ++IG G F+ VY+ + V V K+ L + + REV+ Sbjct: 46 LARVDDFDCA----EKIGAGFFSEVYKVRHRQSGQVMVLKMNKLPSNRSNTL---REVQL 98 Query: 559 LMRVKHKNIVRFLGYC 606 + R++H NI+RF+G C Sbjct: 99 MNRLRHPNILRFMGVC 114
>TESK1_MOUSE (O70146) Dual specificity testis-specific protein kinase 1 (EC| 2.7.12.1) (Testicular protein kinase 1) Length = 627 Score = 35.0 bits (79), Expect = 0.17 Identities = 24/76 (31%), Positives = 41/76 (53%), Gaps = 1/76 (1%) Frame = +1 Query: 382 LSLLDEITCGFSEKQEIGRGGFAVVYE-GSLLNVTVAVKKLTNLHMRDAPEVEYNREVEC 558 L+ +D+ C ++IG G F+ VY+ + V V K+ L + + REV+ Sbjct: 46 LARVDDFDCA----EKIGAGFFSEVYKVRHRQSGQVMVLKMNKLPSNRSNTL---REVQL 98 Query: 559 LMRVKHKNIVRFLGYC 606 + R++H NI+RF+G C Sbjct: 99 MNRLRHPNILRFMGVC 114
>PKNB_LACLA (Q9CEF5) Probable serine/threonine-protein kinase pknB (EC| 2.7.11.1) Length = 627 Score = 35.0 bits (79), Expect = 0.17 Identities = 23/59 (38%), Positives = 31/59 (52%), Gaps = 4/59 (6%) Frame = +1 Query: 424 QEIGRGGFAVVYEGS---LLNVTVAVKKL-TNLHMRDAPEVEYNREVECLMRVKHKNIV 588 +EIGRGG A VY+G L + VA+K L +N D + RE + + H NIV Sbjct: 16 KEIGRGGMANVYQGEDTFLGDRLVAIKVLRSNFENDDIAIARFQREAFAMAELSHPNIV 74
>TESK2_HUMAN (Q96S53) Dual specificity testis-specific protein kinase 2 (EC| 2.7.12.1) (Testicular protein kinase 2) Length = 571 Score = 34.7 bits (78), Expect = 0.23 Identities = 24/76 (31%), Positives = 40/76 (52%), Gaps = 1/76 (1%) Frame = +1 Query: 382 LSLLDEITCGFSEKQEIGRGGFAVVYE-GSLLNVTVAVKKLTNLHMRDAPEVEYNREVEC 558 L+ LD+ TC ++IG G F+ V++ + V K+ L A + +EV+ Sbjct: 53 LTRLDDFTC-----EKIGSGFFSEVFKVRHRASGQVMALKMNTLSSNRANML---KEVQL 104 Query: 559 LMRVKHKNIVRFLGYC 606 + R+ H NI+RF+G C Sbjct: 105 MNRLSHPNILRFMGVC 120
>NTRK1_CHICK (Q91009) High affinity nerve growth factor receptor precursor (EC| 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 1) (Trk-A) (Fragment) Length = 778 Score = 34.7 bits (78), Expect = 0.23 Identities = 21/71 (29%), Positives = 36/71 (50%), Gaps = 7/71 (9%) Frame = +1 Query: 421 KQEIGRGGFAVVYEGSLLNVT-------VAVKKLTNLHMRDAPEVEYNREVECLMRVKHK 579 K E+G G F V+ ++ VAVK L + + +++ RE E L ++H+ Sbjct: 496 KWELGEGAFGKVFLAECSHLLPEQEKTLVAVKALKEV--TENARLDFQREAELLTVLQHE 553 Query: 580 NIVRFLGYCAD 612 +IV+F G C + Sbjct: 554 HIVKFYGVCTE 564
>M3K7_DROME (Q9V3Q6) Mitogen-activated protein kinase kinase kinase 7 (EC| 2.7.11.25) (TGF-beta-activated kinase 1) (dTAK1) Length = 678 Score = 34.7 bits (78), Expect = 0.23 Identities = 24/76 (31%), Positives = 37/76 (48%), Gaps = 3/76 (3%) Frame = +1 Query: 382 LSLLDEITCGFSE---KQEIGRGGFAVVYEGSLLNVTVAVKKLTNLHMRDAPEVEYNREV 552 L L FSE ++++G G + VV + + VAVK+ A + + +EV Sbjct: 6 LDALQAAYVDFSEITLREKVGHGSYGVVCKAVWRDKLVAVKEF----FASAEQKDIEKEV 61 Query: 553 ECLMRVKHKNIVRFLG 600 + L RVKH NI+ G Sbjct: 62 KQLSRVKHPNIIALHG 77
>M3K5_HUMAN (Q99683) Mitogen-activated protein kinase kinase kinase 5 (EC| 2.7.11.25) (MAPK/ERK kinase kinase 5) (MEK kinase 5) (MEKK 5) (Apoptosis signal-regulating kinase 1) (ASK-1) Length = 1374 Score = 34.7 bits (78), Expect = 0.23 Identities = 19/59 (32%), Positives = 35/59 (59%), Gaps = 2/59 (3%) Frame = +1 Query: 430 IGRGGFAVVYEGSLLN--VTVAVKKLTNLHMRDAPEVEYNREVECLMRVKHKNIVRFLG 600 +G+G + +VY G L+ V +A+K++ R + + + E+ +KHKNIV++LG Sbjct: 686 LGKGTYGIVYAGRDLSNQVRIAIKEIPERDSRYSQPL--HEEIALHKHLKHKNIVQYLG 742
>CDC2_ORYLU (Q9DG98) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1) Length = 303 Score = 34.7 bits (78), Expect = 0.23 Identities = 21/60 (35%), Positives = 31/60 (51%), Gaps = 2/60 (3%) Frame = +1 Query: 424 QEIGRGGFAVVYEGSLLNV--TVAVKKLTNLHMRDAPEVEYNREVECLMRVKHKNIVRFL 597 ++IG G + VVY+G + VA+KK+ + REV L +KH N+VR L Sbjct: 8 EKIGEGTYGVVYKGRHKSTGQVVAMKKIRLESEEEGVPSTAVREVSLLQELKHPNVVRLL 67
>CDC2_ORYLA (Q9DGD3) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1) Length = 303 Score = 34.7 bits (78), Expect = 0.23 Identities = 21/60 (35%), Positives = 31/60 (51%), Gaps = 2/60 (3%) Frame = +1 Query: 424 QEIGRGGFAVVYEGSLLNV--TVAVKKLTNLHMRDAPEVEYNREVECLMRVKHKNIVRFL 597 ++IG G + VVY+G + VA+KK+ + REV L +KH N+VR L Sbjct: 8 EKIGEGTYGVVYKGRHKSTGQVVAMKKIRLESEEEGVPSTAVREVSLLQELKHPNVVRLL 67
>CDC2_ORYJA (Q9DGA2) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1) Length = 303 Score = 34.7 bits (78), Expect = 0.23 Identities = 21/60 (35%), Positives = 31/60 (51%), Gaps = 2/60 (3%) Frame = +1 Query: 424 QEIGRGGFAVVYEGSLLNV--TVAVKKLTNLHMRDAPEVEYNREVECLMRVKHKNIVRFL 597 ++IG G + VVY+G + VA+KK+ + REV L +KH N+VR L Sbjct: 8 EKIGEGTYGVVYKGRHKSTGQVVAMKKIRLESEEEGVPSTAVREVSLLQELKHPNVVRLL 67
>CDC2_ORYCU (Q9DGA5) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1) Length = 303 Score = 34.7 bits (78), Expect = 0.23 Identities = 21/60 (35%), Positives = 31/60 (51%), Gaps = 2/60 (3%) Frame = +1 Query: 424 QEIGRGGFAVVYEGSLLNV--TVAVKKLTNLHMRDAPEVEYNREVECLMRVKHKNIVRFL 597 ++IG G + VVY+G + VA+KK+ + REV L +KH N+VR L Sbjct: 8 EKIGEGTYGVVYKGRHKSTGQVVAMKKIRLESEEEGVPSTAVREVSLLQELKHPNVVRLL 67
>ABL1_CAEEL (P03949) Tyrosine-protein kinase abl-1 (EC 2.7.10.2)| Length = 1224 Score = 34.7 bits (78), Expect = 0.23 Identities = 23/62 (37%), Positives = 32/62 (51%), Gaps = 2/62 (3%) Frame = +1 Query: 427 EIGRGGFAVVYEG--SLLNVTVAVKKLTNLHMRDAPEVEYNREVECLMRVKHKNIVRFLG 600 ++G G + VYEG + T+AVK L M P E+ E + + HKN+VR LG Sbjct: 316 KLGGGQYGDVYEGYWKRHDCTIAVKALKEDAM---PLHEFLAEAAIMKDLHHKNLVRLLG 372 Query: 601 YC 606 C Sbjct: 373 VC 374
>M3K5_MOUSE (O35099) Mitogen-activated protein kinase kinase kinase 5 (EC| 2.7.11.25) (MAPK/ERK kinase kinase 5) (MEK kinase 5) (MEKK 5) (Apoptosis signal-regulating kinase 1) (ASK-1) Length = 1380 Score = 34.7 bits (78), Expect = 0.23 Identities = 19/59 (32%), Positives = 35/59 (59%), Gaps = 2/59 (3%) Frame = +1 Query: 430 IGRGGFAVVYEGSLLN--VTVAVKKLTNLHMRDAPEVEYNREVECLMRVKHKNIVRFLG 600 +G+G + +VY G L+ V +A+K++ R + + + E+ +KHKNIV++LG Sbjct: 693 LGKGTYGIVYAGRDLSNQVRIAIKEIPERDSRYSQPL--HEEIALHKHLKHKNIVQYLG 749
>BUR1_DEBHA (Q6BV06) Serine/threonine-protein kinase BUR1 (EC 2.7.11.22) (EC| 2.7.11.23) Length = 608 Score = 34.7 bits (78), Expect = 0.23 Identities = 18/60 (30%), Positives = 34/60 (56%), Gaps = 2/60 (3%) Frame = +1 Query: 424 QEIGRGGFAVVYEGSLLNVT--VAVKKLTNLHMRDAPEVEYNREVECLMRVKHKNIVRFL 597 Q++G+G F VV + + VA+K+L N ++ + RE+ L ++ HKNI++ + Sbjct: 43 QKLGQGTFGVVQKARNIKTKELVALKQLINHSAKEGFPITAMREITILKKLNHKNILKII 102
>PHO85_YEAST (P17157) Negative regulator of the PHO system (EC 2.7.11.22)| (Serine/threonine-protein kinase PHO85) Length = 305 Score = 34.7 bits (78), Expect = 0.23 Identities = 20/62 (32%), Positives = 34/62 (54%), Gaps = 2/62 (3%) Frame = +1 Query: 412 FSEKQEIGRGGFAVVYEG--SLLNVTVAVKKLTNLHMRDAPEVEYNREVECLMRVKHKNI 585 F + +++G G +A VY+G V VA+K++ L + RE+ + +KH+NI Sbjct: 7 FKQLEKLGNGTYATVYKGLNKTTGVYVALKEV-KLDSEEGTPSTAIREISLMKELKHENI 65 Query: 586 VR 591 VR Sbjct: 66 VR 67
>AVR2A_RAT (P38444) Activin receptor type 2A precursor (EC 2.7.11.30) (Activin| receptor type IIA) (ACTR-IIA) Length = 513 Score = 34.7 bits (78), Expect = 0.23 Identities = 21/55 (38%), Positives = 31/55 (56%) Frame = +1 Query: 436 RGGFAVVYEGSLLNVTVAVKKLTNLHMRDAPEVEYNREVECLMRVKHKNIVRFLG 600 RG F V++ LLN VAVK ++D + EV L +KH+NI++F+G Sbjct: 200 RGRFGCVWKAQLLNEYVAVKIFP---IQDKQSWQNEYEVYSLPGMKHENILQFIG 251
>AVR2A_MOUSE (P27038) Activin receptor type 2A precursor (EC 2.7.11.30) (Activin| receptor type IIA) (ACTR-IIA) Length = 513 Score = 34.7 bits (78), Expect = 0.23 Identities = 21/55 (38%), Positives = 31/55 (56%) Frame = +1 Query: 436 RGGFAVVYEGSLLNVTVAVKKLTNLHMRDAPEVEYNREVECLMRVKHKNIVRFLG 600 RG F V++ LLN VAVK ++D + EV L +KH+NI++F+G Sbjct: 200 RGRFGCVWKAQLLNEYVAVKIFP---IQDKQSWQNEYEVYSLPGMKHENILQFIG 251
>AVR2A_HUMAN (P27037) Activin receptor type 2A precursor (EC 2.7.11.30) (Activin| receptor type IIA) (ACTR-IIA) (ACTRIIA) Length = 513 Score = 34.7 bits (78), Expect = 0.23 Identities = 21/55 (38%), Positives = 31/55 (56%) Frame = +1 Query: 436 RGGFAVVYEGSLLNVTVAVKKLTNLHMRDAPEVEYNREVECLMRVKHKNIVRFLG 600 RG F V++ LLN VAVK ++D + EV L +KH+NI++F+G Sbjct: 200 RGRFGCVWKAQLLNEYVAVKIFP---IQDKQSWQNEYEVYSLPGMKHENILQFIG 251
>AVR2A_BOVIN (Q28043) Activin receptor type 2A precursor (EC 2.7.11.30) (Activin| receptor type IIA) (ACTR-IIA) Length = 513 Score = 34.7 bits (78), Expect = 0.23 Identities = 21/55 (38%), Positives = 31/55 (56%) Frame = +1 Query: 436 RGGFAVVYEGSLLNVTVAVKKLTNLHMRDAPEVEYNREVECLMRVKHKNIVRFLG 600 RG F V++ LLN VAVK ++D + EV L +KH+NI++F+G Sbjct: 200 RGRFGCVWKAQLLNEYVAVKIFP---IQDKQSWQNEYEVYSLPGMKHENILQFIG 251
>MIL_AVIMH (P00531) Serine/threonine-protein kinase transforming protein mil| (EC 2.7.11.1) Length = 380 Score = 34.3 bits (77), Expect = 0.30 Identities = 21/58 (36%), Positives = 29/58 (50%) Frame = +1 Query: 430 IGRGGFAVVYEGSLLNVTVAVKKLTNLHMRDAPEVEYNREVECLMRVKHKNIVRFLGY 603 IG G F VY+G + VAVK L + + EV L + +H NI+ F+GY Sbjct: 88 IGSGSFGTVYKGKW-HGDVAVKILKVVDPTPEQFQAFRNEVAVLRKTRHVNILLFMGY 144
>TAOK2_XENLA (Q6GPK9) Serine/threonine-protein kinase TAO2 (EC 2.7.11.1)| (Thousand and one amino acid protein 2) Length = 1025 Score = 34.3 bits (77), Expect = 0.30 Identities = 22/82 (26%), Positives = 42/82 (51%), Gaps = 3/82 (3%) Frame = +1 Query: 364 EPKALPLSLLDEITCGFSEKQEIGRGGFAVVYEGSLL--NVTVAVKKLTNLHMRDAPE-V 534 +P+ L D+ F++ +EIG G F VY + N VA+KK++ + + Sbjct: 12 DPEVAELFFKDDPEKLFADLREIGHGSFGAVYFARDIRNNEVVAIKKMSYSGKQSNEKWQ 71 Query: 535 EYNREVECLMRVKHKNIVRFLG 600 + +EV+ L +++H N + + G Sbjct: 72 DIIKEVKFLQKLRHPNTIEYKG 93
>CDC22_MEDSA (Q05006) Cell division control protein 2 homolog 2 (EC 2.7.11.22)| Length = 294 Score = 34.3 bits (77), Expect = 0.30 Identities = 19/62 (30%), Positives = 33/62 (53%), Gaps = 2/62 (3%) Frame = +1 Query: 412 FSEKQEIGRGGFAVVYEGS--LLNVTVAVKKLTNLHMRDAPEVEYNREVECLMRVKHKNI 585 + + ++IG G + VVY+ N T+A+KK+ + RE+ L ++H+NI Sbjct: 4 YEKVEKIGEGTYGVVYKARDRATNETIALKKIRLEQEDEGVPSTAIREISLLKEMQHRNI 63 Query: 586 VR 591 VR Sbjct: 64 VR 65
>RAF1_CHICK (P05625) RAF proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (RAF-1) (C-RAF) (MIL proto-oncogene serine/threonine-protein kinase) (C-MIL) Length = 647 Score = 34.3 bits (77), Expect = 0.30 Identities = 21/58 (36%), Positives = 29/58 (50%) Frame = +1 Query: 430 IGRGGFAVVYEGSLLNVTVAVKKLTNLHMRDAPEVEYNREVECLMRVKHKNIVRFLGY 603 IG G F VY+G + VAVK L + + EV L + +H NI+ F+GY Sbjct: 355 IGSGSFGTVYKGKW-HGDVAVKILKVVDPTPEQFQAFRNEVAVLRKTRHVNILLFMGY 411
>RAF_MSV36 (P00532) Serine/threonine-protein kinase transforming protein raf| (EC 2.7.11.1) Length = 323 Score = 34.3 bits (77), Expect = 0.30 Identities = 21/58 (36%), Positives = 29/58 (50%) Frame = +1 Query: 430 IGRGGFAVVYEGSLLNVTVAVKKLTNLHMRDAPEVEYNREVECLMRVKHKNIVRFLGY 603 IG G F VY+G + VAVK L + + EV L + +H NI+ F+GY Sbjct: 30 IGSGSFGTVYKGKW-HGDVAVKILKVVDPTPEQLQAFRNEVAVLRKTRHVNILLFMGY 86
>MATK_RAT (P41243) Megakaryocyte-associated tyrosine-protein kinase (EC| 2.7.10.2) (Tyrosine-protein kinase CTK) (Protein kinase BATK) Length = 467 Score = 34.3 bits (77), Expect = 0.30 Identities = 19/58 (32%), Positives = 29/58 (50%) Frame = +1 Query: 427 EIGRGGFAVVYEGSLLNVTVAVKKLTNLHMRDAPEVEYNREVECLMRVKHKNIVRFLG 600 +IG G F V +G L VAVK + D + E + +++H+N+VR LG Sbjct: 199 QIGEGEFGAVLQGEYLGQKVAVKNI----KCDVTAQAFLDETAVMTKLQHRNLVRLLG 252
>MATK_MOUSE (P41242) Megakaryocyte-associated tyrosine-protein kinase (EC| 2.7.10.2) (Tyrosine-protein kinase CTK) (Protein kinase NTK) Length = 505 Score = 34.3 bits (77), Expect = 0.30 Identities = 19/58 (32%), Positives = 29/58 (50%) Frame = +1 Query: 427 EIGRGGFAVVYEGSLLNVTVAVKKLTNLHMRDAPEVEYNREVECLMRVKHKNIVRFLG 600 +IG G F V +G L VAVK + D + E + +++H+N+VR LG Sbjct: 238 QIGEGEFGAVLQGEYLGQKVAVKNI----KCDVTAQAFLDETAVMTKLQHRNLVRLLG 291
>CDK10_HUMAN (Q15131) Cell division protein kinase 10 (EC 2.7.11.22)| (Serine/threonine-protein kinase PISSLRE) Length = 360 Score = 34.3 bits (77), Expect = 0.30 Identities = 19/61 (31%), Positives = 32/61 (52%), Gaps = 2/61 (3%) Frame = +1 Query: 412 FSEKQEIGRGGFAVVYEG--SLLNVTVAVKKLTNLHMRDAPEVEYNREVECLMRVKHKNI 585 F + IG G + +VY + + VA+KK+ +D + RE+ L+R++H NI Sbjct: 39 FEKLNRIGEGTYGIVYRARDTQTDEIVALKKVRMDKEKDGIPISSLREITLLLRLRHPNI 98 Query: 586 V 588 V Sbjct: 99 V 99
>PLK3_CAEEL (Q20845) Serine/threonine-protein kinase plk-3 (EC 2.7.11.21)| (Polo-like kinase 3) Length = 615 Score = 34.3 bits (77), Expect = 0.30 Identities = 23/83 (27%), Positives = 43/83 (51%), Gaps = 3/83 (3%) Frame = +1 Query: 376 LPLSLLDEITCGFSEKQEIGRGGFAVVYEGSLL--NVTVAVKKLTN-LHMRDAPEVEYNR 546 +P + D++ + + +G GGFA +E L N +AVK + + ++ + R Sbjct: 23 VPPIIYDDMQVPYEKGAFLGEGGFAHCFEFRKLDCNDRLAVKVVPKVILLKSTAREKLTR 82 Query: 547 EVECLMRVKHKNIVRFLGYCADT 615 EVE ++ H+NIV+F + D+ Sbjct: 83 EVEIHRQLSHRNIVQFHHFFEDS 105
>PCTK1_MOUSE (Q04735) Serine/threonine-protein kinase PCTAIRE-1 (EC 2.7.11.22)| (PCTAIRE-motif protein kinase 1) (CRK5) Length = 496 Score = 34.3 bits (77), Expect = 0.30 Identities = 34/107 (31%), Positives = 52/107 (48%), Gaps = 8/107 (7%) Frame = +1 Query: 292 LQMDIQMIPSTVEDL--ESMVIDESAEPKALPLSLLDEITCG----FSEKQEIGRGGFAV 453 L DI++ +E L S + D+ + +SL EI G + + ++G G +A Sbjct: 120 LPADIRLPEGYLEKLTLNSPIFDKPLSRRLRRVSL-SEIGFGKLETYIKLDKLGEGTYAT 178 Query: 454 VYEGS--LLNVTVAVKKLTNLHMRDAPEVEYNREVECLMRVKHKNIV 588 VY+G L + VA+K++ H AP REV L +KH NIV Sbjct: 179 VYKGKSKLTDNLVALKEIRLEHEEGAPCTAI-REVSLLKDLKHANIV 224
>PCTK1_HUMAN (Q00536) Serine/threonine-protein kinase PCTAIRE-1 (EC 2.7.11.22)| (PCTAIRE-motif protein kinase 1) Length = 496 Score = 34.3 bits (77), Expect = 0.30 Identities = 34/107 (31%), Positives = 52/107 (48%), Gaps = 8/107 (7%) Frame = +1 Query: 292 LQMDIQMIPSTVEDL--ESMVIDESAEPKALPLSLLDEITCG----FSEKQEIGRGGFAV 453 L DI++ +E L S + D+ + +SL EI G + + ++G G +A Sbjct: 120 LPADIRLPEGYLEKLTLNSPIFDKPLSRRLRRVSL-SEIGFGKLETYIKLDKLGEGTYAT 178 Query: 454 VYEGS--LLNVTVAVKKLTNLHMRDAPEVEYNREVECLMRVKHKNIV 588 VY+G L + VA+K++ H AP REV L +KH NIV Sbjct: 179 VYKGKSKLTDNLVALKEIRLEHEEGAPCTAI-REVSLLKDLKHANIV 224
>CDC21_MEDSA (P24923) Cell division control protein 2 homolog 1 (EC 2.7.11.22)| (EC 2.7.11.23) (Fragment) Length = 291 Score = 34.3 bits (77), Expect = 0.30 Identities = 19/58 (32%), Positives = 32/58 (55%), Gaps = 2/58 (3%) Frame = +1 Query: 424 QEIGRGGFAVVYEGS--LLNVTVAVKKLTNLHMRDAPEVEYNREVECLMRVKHKNIVR 591 ++IG G + VVY+ + N T+A+KK+ + RE+ L ++H+NIVR Sbjct: 5 EKIGEGTYGVVYKARDRVTNETIALKKIRLEQEDEGVPSTAIREISLLKEMQHRNIVR 62
>RAF1_RAT (P11345) RAF proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (Raf-1) (C-RAF) (cRaf) Length = 648 Score = 34.3 bits (77), Expect = 0.30 Identities = 21/58 (36%), Positives = 29/58 (50%) Frame = +1 Query: 430 IGRGGFAVVYEGSLLNVTVAVKKLTNLHMRDAPEVEYNREVECLMRVKHKNIVRFLGY 603 IG G F VY+G + VAVK L + + EV L + +H NI+ F+GY Sbjct: 355 IGSGSFGTVYKGKW-HGDVAVKILKVVDPTPEQLQAFRNEVAVLRKTRHVNILLFMGY 411
>RAF1_MOUSE (Q99N57) RAF proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (Raf-1) (C-RAF) (cRaf) Length = 648 Score = 34.3 bits (77), Expect = 0.30 Identities = 21/58 (36%), Positives = 29/58 (50%) Frame = +1 Query: 430 IGRGGFAVVYEGSLLNVTVAVKKLTNLHMRDAPEVEYNREVECLMRVKHKNIVRFLGY 603 IG G F VY+G + VAVK L + + EV L + +H NI+ F+GY Sbjct: 355 IGSGSFGTVYKGKW-HGDVAVKILKVVDPTPEQLQAFRNEVAVLRKTRHVNILLFMGY 411
>RAF1_HUMAN (P04049) RAF proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (Raf-1) (C-RAF) (cRaf) Length = 648 Score = 34.3 bits (77), Expect = 0.30 Identities = 21/58 (36%), Positives = 29/58 (50%) Frame = +1 Query: 430 IGRGGFAVVYEGSLLNVTVAVKKLTNLHMRDAPEVEYNREVECLMRVKHKNIVRFLGY 603 IG G F VY+G + VAVK L + + EV L + +H NI+ F+GY Sbjct: 355 IGSGSFGTVYKGKW-HGDVAVKILKVVDPTPEQFQAFRNEVAVLRKTRHVNILLFMGY 411
>ULK2_HUMAN (Q8IYT8) Serine/threonine-protein kinase ULK2 (EC 2.7.11.1)| (Unc-51-like kinase 2) Length = 1036 Score = 34.3 bits (77), Expect = 0.30 Identities = 18/62 (29%), Positives = 36/62 (58%), Gaps = 3/62 (4%) Frame = +1 Query: 412 FSEKQEIGRGGFAVVYEGSLLNVT---VAVKKLTNLHMRDAPEVEYNREVECLMRVKHKN 582 +S++ +G G FAVV+ G T VA+K + ++ + ++ +E++ L ++H+N Sbjct: 9 YSKRDLVGHGAFAVVFRGRHRQKTDWEVAIKSINKKNLSKS-QILLGKEIKILKELQHEN 67 Query: 583 IV 588 IV Sbjct: 68 IV 69
>TESK1_HUMAN (Q15569) Dual specificity testis-specific protein kinase 1 (EC| 2.7.12.1) (Testicular protein kinase 1) Length = 626 Score = 34.3 bits (77), Expect = 0.30 Identities = 24/76 (31%), Positives = 40/76 (52%), Gaps = 1/76 (1%) Frame = +1 Query: 382 LSLLDEITCGFSEKQEIGRGGFAVVYE-GSLLNVTVAVKKLTNLHMRDAPEVEYNREVEC 558 L+ +D+ C ++IG G F+ VY+ + V V K+ L + REV+ Sbjct: 51 LARVDDFHCA----EKIGAGFFSEVYKVRHRQSGQVMVLKMNKLPSNRGNTL---REVQL 103 Query: 559 LMRVKHKNIVRFLGYC 606 + R++H NI+RF+G C Sbjct: 104 MNRLRHPNILRFMGVC 119
>M3KL4_HUMAN (Q5TCX8) Mitogen-activated protein kinase kinase kinase (EC| 2.7.11.25) (Mixed lineage kinase 4) Length = 1036 Score = 34.3 bits (77), Expect = 0.30 Identities = 21/64 (32%), Positives = 27/64 (42%), Gaps = 2/64 (3%) Frame = +1 Query: 421 KQEIGRGGFAVVYEGSLLNVTVAVKKLTNLHMRDAPEV--EYNREVECLMRVKHKNIVRF 594 K+ IG GGF VY + VAVK +DA RE ++H NI+ Sbjct: 127 KELIGAGGFGQVYRATWQGQEVAVKAARQDPEQDAAAAAESVRREARLFAMLRHPNIIEL 186 Query: 595 LGYC 606 G C Sbjct: 187 RGVC 190
>PHO85_KLULA (Q92241) Negative regulator of the PHO system (EC 2.7.11.22)| (Serine/threonine-protein kinase PHO85) Length = 304 Score = 34.3 bits (77), Expect = 0.30 Identities = 20/62 (32%), Positives = 33/62 (53%), Gaps = 2/62 (3%) Frame = +1 Query: 412 FSEKQEIGRGGFAVVYEG--SLLNVTVAVKKLTNLHMRDAPEVEYNREVECLMRVKHKNI 585 F + +++G G +A VY+G V VA+K++ L + RE+ + +KH NI Sbjct: 7 FKQLEKVGNGTYATVYKGLNKTTGVYVALKEV-KLDSEEGTPSTAIREISLMKELKHDNI 65 Query: 586 VR 591 VR Sbjct: 66 VR 67
>CDK3_MOUSE (Q80YP0) Truncated cell division protein kinase 3 homolog| Length = 186 Score = 33.9 bits (76), Expect = 0.39 Identities = 21/65 (32%), Positives = 34/65 (52%), Gaps = 3/65 (4%) Frame = +1 Query: 412 FSEKQEIGRGGFAVVYEG--SLLNVTVAVKKLT-NLHMRDAPEVEYNREVECLMRVKHKN 582 F + ++IG G + VVY+ + VA+KK+ +L P RE+ L +KH N Sbjct: 4 FQKVEKIGEGTYGVVYKARNKVTGQLVALKKIRLDLEAEGVPSTAV-REISLLKELKHPN 62 Query: 583 IVRFL 597 I++ L Sbjct: 63 IIKLL 67
>CDC2_CHERU (P93101) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34cdc2) Length = 294 Score = 33.9 bits (76), Expect = 0.39 Identities = 19/62 (30%), Positives = 33/62 (53%), Gaps = 2/62 (3%) Frame = +1 Query: 412 FSEKQEIGRGGFAVVYEG--SLLNVTVAVKKLTNLHMRDAPEVEYNREVECLMRVKHKNI 585 + + ++IG G + VVY+ + N T+A+KK+ + RE+ L ++H NI Sbjct: 4 YEKVEKIGEGTYGVVYKARDKVTNETIALKKIRLEQEDEGVPSTAIREISLLKEMQHGNI 63 Query: 586 VR 591 VR Sbjct: 64 VR 65
>ROR2_DROME (Q9V6K3) Tyrosine-protein kinase transmembrane receptor Ror2| precursor (EC 2.7.10.1) (Neurospecific receptor tyrosine kinase) Length = 724 Score = 33.9 bits (76), Expect = 0.39 Identities = 22/69 (31%), Positives = 33/69 (47%), Gaps = 7/69 (10%) Frame = +1 Query: 424 QEIGRGGFAVVYEGSLLNVT-------VAVKKLTNLHMRDAPEVEYNREVECLMRVKHKN 582 + +G+G F V++ + VAVK L + D ++++ RE L H N Sbjct: 445 RSLGQGAFGRVFQARAPGLVPDQEDLLVAVKMLKD-DASDQMQMDFEREACLLAEFDHPN 503 Query: 583 IVRFLGYCA 609 IVR LG CA Sbjct: 504 IVRLLGVCA 512
>MPK7_ARATH (Q39027) Mitogen-activated protein kinase homolog 7 (EC 2.7.11.24)| (MAP kinase 7) (AtMPK7) Length = 368 Score = 33.9 bits (76), Expect = 0.39 Identities = 21/68 (30%), Positives = 34/68 (50%), Gaps = 2/68 (2%) Frame = +1 Query: 391 LDEITCGFSEKQEIGRGGFAVVYEG--SLLNVTVAVKKLTNLHMRDAPEVEYNREVECLM 564 L EI + + IGRG + VV N VA+KK+ N+ + RE++ L Sbjct: 25 LFEIDTKYVPIKPIGRGAYGVVCSSINRETNERVAIKKIHNVFENRVDALRTLRELKLLR 84 Query: 565 RVKHKNIV 588 V+H+N++ Sbjct: 85 HVRHENVI 92
>BMX_HUMAN (P51813) Cytoplasmic tyrosine-protein kinase BMX (EC 2.7.10.2)| (Bone marrow tyrosine kinase gene in chromosome X protein) (Epithelial and endothelial tyrosine kinase) (ETK) (NTK38) Length = 675 Score = 33.9 bits (76), Expect = 0.39 Identities = 21/63 (33%), Positives = 33/63 (52%), Gaps = 1/63 (1%) Frame = +1 Query: 424 QEIGRGGFAVVYEGSLLN-VTVAVKKLTNLHMRDAPEVEYNREVECLMRVKHKNIVRFLG 600 +E+G G F VV G VAVK + M E E+ +E + +M++ H +V+F G Sbjct: 421 KELGSGQFGVVQLGKWKGQYDVAVKMIKEGSMS---EDEFFQEAQTMMKLSHPKLVKFYG 477 Query: 601 YCA 609 C+ Sbjct: 478 VCS 480
>BMX_MOUSE (P97504) Cytoplasmic tyrosine-protein kinase BMX (EC 2.7.10.2)| (Bone marrow tyrosine kinase gene in chromosome X protein homolog) Length = 651 Score = 33.9 bits (76), Expect = 0.39 Identities = 21/63 (33%), Positives = 33/63 (52%), Gaps = 1/63 (1%) Frame = +1 Query: 424 QEIGRGGFAVVYEGSLLN-VTVAVKKLTNLHMRDAPEVEYNREVECLMRVKHKNIVRFLG 600 +E+G G F VV G VAVK + M E E+ +E + +M++ H +V+F G Sbjct: 397 KELGNGQFGVVQLGQWKGQYDVAVKMIKEGAMS---EDEFFQEAQTMMKLSHPKLVKFYG 453 Query: 601 YCA 609 C+ Sbjct: 454 VCS 456
>RYK_AVIR3 (P33497) Tyrosine-protein kinase transforming protein RYK (EC| 2.7.10.1) Length = 442 Score = 33.9 bits (76), Expect = 0.39 Identities = 21/68 (30%), Positives = 29/68 (42%), Gaps = 7/68 (10%) Frame = +1 Query: 430 IGRGGFAVVYEGSLLN-------VTVAVKKLTNLHMRDAPEVEYNREVECLMRVKHKNIV 588 +G G F V EG L V V KL N R+ E + E C+ H N++ Sbjct: 51 LGEGEFGSVMEGRLSQPEGTPQKVAVKTMKLDNFSHREIEE--FLSEAACIKDFDHPNVI 108 Query: 589 RFLGYCAD 612 + LG C + Sbjct: 109 KLLGVCIE 116
>RAF1_XENLA (P09560) RAF proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (C-RAF) Length = 638 Score = 33.9 bits (76), Expect = 0.39 Identities = 22/61 (36%), Positives = 32/61 (52%), Gaps = 3/61 (4%) Frame = +1 Query: 430 IGRGGFAVVYEGSLL-NVTVAVKKLTNLHMRDAPEV--EYNREVECLMRVKHKNIVRFLG 600 IG G F VY+G +V V + K+T+ PE + EV L + +H NI+ F+G Sbjct: 346 IGSGSFGTVYKGKWHGDVAVKILKVTD----PTPEQLQAFRNEVAVLRKTRHVNILLFMG 401 Query: 601 Y 603 Y Sbjct: 402 Y 402
>M3K9_HUMAN (P80192) Mitogen-activated protein kinase kinase kinase 9 (EC| 2.7.11.25) (Mixed lineage kinase 1) Length = 1104 Score = 33.9 bits (76), Expect = 0.39 Identities = 23/78 (29%), Positives = 35/78 (44%), Gaps = 2/78 (2%) Frame = +1 Query: 379 PLSLLDEITCGFSEKQEIGRGGFAVVYEGSLLNVTVAVKKLTNLHMRDAPEVEYN--REV 552 P+ LL+ + ++ IG GGF VY + VAVK + D + N +E Sbjct: 133 PIQLLEIDFAELTLEEIIGIGGFGKVYRAFWIGDEVAVKAARHDPDEDISQTIENVRQEA 192 Query: 553 ECLMRVKHKNIVRFLGYC 606 + +KH NI+ G C Sbjct: 193 KLFAMLKHPNIIALRGVC 210
>MOS_CHICK (P10741) Serine/threonine-protein kinase mos (EC 2.7.11.1) (Oocyte| maturation factor mos) Length = 349 Score = 33.9 bits (76), Expect = 0.39 Identities = 22/61 (36%), Positives = 32/61 (52%), Gaps = 5/61 (8%) Frame = +1 Query: 424 QEIGRGGFAVVYEGSLLNVTVAVKKL-----TNLHMRDAPEVEYNREVECLMRVKHKNIV 588 Q +G GGF VY+ + VTVAVK++ L R + E N + R++H N+V Sbjct: 68 QPLGSGGFGAVYKATYHGVTVAVKQVKKSSKNRLASRQSFWAELN-----VARLQHDNVV 122 Query: 589 R 591 R Sbjct: 123 R 123
>MOS_CICNG (Q90XV8) Serine/threonine-protein kinase mos (EC 2.7.11.1) (Oocyte| maturation factor mos) (Fragment) Length = 200 Score = 33.9 bits (76), Expect = 0.39 Identities = 22/61 (36%), Positives = 32/61 (52%), Gaps = 5/61 (8%) Frame = +1 Query: 424 QEIGRGGFAVVYEGSLLNVTVAVKKLTN-----LHMRDAPEVEYNREVECLMRVKHKNIV 588 Q +G GGF VY+ + TVAVK++ N L R + E N + R++H N+V Sbjct: 6 QPLGSGGFGSVYKATYHGATVAVKQVKNSSKNRLASRQSFWAELN-----VARLQHNNVV 60 Query: 589 R 591 R Sbjct: 61 R 61
>TAOK3_XENLA (Q6DD27) Serine/threonine-protein kinase TAO3 (EC 2.7.11.1)| (Thousand and one amino acid protein 3) Length = 896 Score = 33.9 bits (76), Expect = 0.39 Identities = 22/66 (33%), Positives = 34/66 (51%), Gaps = 3/66 (4%) Frame = +1 Query: 412 FSEKQEIGRGGFAVVY--EGSLLNVTVAVKKLT-NLHMRDAPEVEYNREVECLMRVKHKN 582 F + EIG G F VY S N VAVKK++ + + + +EV+ L ++KH N Sbjct: 24 FVDLHEIGHGSFGAVYFATNSTTNEIVAVKKMSYSGKQMNEKWQDIIKEVKFLQQLKHPN 83 Query: 583 IVRFLG 600 + + G Sbjct: 84 TIEYKG 89
>BUR1_GIBZE (Q4I5U9) Serine/threonine-protein kinase BUR1 (EC 2.7.11.22) (EC| 2.7.11.23) Length = 473 Score = 33.9 bits (76), Expect = 0.39 Identities = 19/57 (33%), Positives = 30/57 (52%), Gaps = 2/57 (3%) Frame = +1 Query: 427 EIGRGGFAVVYEGSL--LNVTVAVKKLTNLHMRDAPEVEYNREVECLMRVKHKNIVR 591 ++G G F V+ L VA+KK+ H +D + RE++ L + HKNI+R Sbjct: 42 KLGEGTFGEVHRARLRKTGALVALKKIIMHHEKDGFPITALREIKLLKLLSHKNILR 98
>ACK1_MOUSE (O54967) Activated CDC42 kinase 1 (EC 2.7.10.2) (ACK-1)| (Non-receptor protein tyrosine kinase Ack) (Tyrosine kinase non-receptor protein 2) Length = 1055 Score = 33.9 bits (76), Expect = 0.39 Identities = 30/94 (31%), Positives = 44/94 (46%), Gaps = 13/94 (13%) Frame = +1 Query: 358 SAEPKALP-LSLLDEITCGFSEK-----QEIGRGGFAVVYEGSL-----LNVTVAVKKLT 504 S P +LP L +TC EK +++G G F VV G V+VAVK L Sbjct: 102 SPTPGSLPGEGTLQSLTCLIGEKDLRLLEKLGDGSFGVVRRGEWDAPAGKTVSVAVKCLK 161 Query: 505 NLHMRDAPEV--EYNREVECLMRVKHKNIVRFLG 600 + PE ++ REV + + H+N++R G Sbjct: 162 P-DVLSQPEAMDDFIREVNAMHSLDHRNLIRLYG 194
>MATK_HUMAN (P42679) Megakaryocyte-associated tyrosine-protein kinase (EC| 2.7.10.2) (Tyrosine-protein kinase CTK) (Protein kinase HYL) (Hematopoietic consensus tyrosine-lacking kinase) Length = 507 Score = 33.9 bits (76), Expect = 0.39 Identities = 19/58 (32%), Positives = 29/58 (50%) Frame = +1 Query: 427 EIGRGGFAVVYEGSLLNVTVAVKKLTNLHMRDAPEVEYNREVECLMRVKHKNIVRFLG 600 +IG G F V +G L VAVK + D + E + +++H+N+VR LG Sbjct: 240 QIGEGEFGAVLQGEYLGQKVAVKNI----KCDVTAQAFLDETAVMTKMQHENLVRLLG 293
>PCTK3_HUMAN (Q07002) Serine/threonine-protein kinase PCTAIRE-3 (EC 2.7.11.22)| (PCTAIRE-motif protein kinase 3) Length = 472 Score = 33.9 bits (76), Expect = 0.39 Identities = 33/109 (30%), Positives = 53/109 (48%), Gaps = 10/109 (9%) Frame = +1 Query: 292 LQMDIQMIPSTVEDLESMVIDESAEPKALPL----SLLDEITCG----FSEKQEIGRGGF 447 L MDI++ E L+ + ++ PK L + L +I G + + ++G G + Sbjct: 97 LPMDIRL---PQEFLQKLQMESPDLPKPLSRMSRRASLSDIGFGKLETYVKLDKLGEGTY 153 Query: 448 AVVYEG--SLLNVTVAVKKLTNLHMRDAPEVEYNREVECLMRVKHKNIV 588 A V++G L+ VA+K++ H AP REV L +KH NIV Sbjct: 154 ATVFKGRSKLMENLVALKEIRLEHEEGAPCTAI-REVSLLKNLKHANIV 201
>ATG1_SCHPO (Q9Y7T4) Serine/threonine-protein kinase atg1 (EC 2.7.11.1)| (Autophagy-related protein 1) Length = 830 Score = 33.5 bits (75), Expect = 0.51 Identities = 16/61 (26%), Positives = 31/61 (50%), Gaps = 2/61 (3%) Frame = +1 Query: 421 KQEIGRGGFAVVYEG--SLLNVTVAVKKLTNLHMRDAPEVEYNREVECLMRVKHKNIVRF 594 + EIGRG FA+VY+G + N +++K + + E+ L ++H ++V Sbjct: 17 RSEIGRGSFAIVYKGKHTETNRVISIKSVLTKKLTKKLLENLESEISILKEIRHVHVVEL 76 Query: 595 L 597 + Sbjct: 77 I 77
>ERBB4_RAT (Q62956) Receptor tyrosine-protein kinase erbB-4 precursor (EC| 2.7.10.1) Length = 1308 Score = 33.5 bits (75), Expect = 0.51 Identities = 22/65 (33%), Positives = 30/65 (46%), Gaps = 6/65 (9%) Frame = +1 Query: 430 IGRGGFAVVY------EGSLLNVTVAVKKLTNLHMRDAPEVEYNREVECLMRVKHKNIVR 591 +G G F VY EG + + VA+K L A VE+ E + V H ++VR Sbjct: 724 LGSGAFGTVYKGIWVPEGETVKIPVAIKILNETTGPKA-NVEFMDEALIMASVDHPHLVR 782 Query: 592 FLGYC 606 LG C Sbjct: 783 LLGVC 787
>CDC2_DROME (P23572) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) Length = 297 Score = 33.5 bits (75), Expect = 0.51 Identities = 21/61 (34%), Positives = 32/61 (52%), Gaps = 2/61 (3%) Frame = +1 Query: 412 FSEKQEIGRGGFAVVYEG--SLLNVTVAVKKLTNLHMRDAPEVEYNREVECLMRVKHKNI 585 F + ++IG G + VVY+G L VA+KK+ + RE+ L +KH+NI Sbjct: 4 FEKIEKIGEGTYGVVYKGRNRLTGQIVAMKKIRLESDDEGVPSTAIREISLLKELKHENI 63 Query: 586 V 588 V Sbjct: 64 V 64
>PKN1_MYXXA (P33973) Serine/threonine-protein kinase pkn1 (EC 2.7.11.1)| Length = 693 Score = 33.5 bits (75), Expect = 0.51 Identities = 26/86 (30%), Positives = 44/86 (51%), Gaps = 9/86 (10%) Frame = +1 Query: 358 SAEPKALPLSLLDE----ITCG-FSEKQEIGRGGFAVVYEGSLLNV--TVAVKKLTNLHM 516 +A P+ P+ + + CG F + +GRGG VY G +++ VAVK L + H+ Sbjct: 36 TAHPRCAPVVEAQDPLVGVRCGSFRLVRRLGRGGMGAVYLGEHVSIGSRVAVKVL-HAHL 94 Query: 517 RDAPEV--EYNREVECLMRVKHKNIV 588 PE+ ++ E + + H+NIV Sbjct: 95 TMYPELVQRFHAEARAVNLIGHENIV 120
>CDC2A_ARATH (P24100) Cell division control protein 2 homolog A (EC 2.7.11.22)| (EC 2.7.11.23) Length = 294 Score = 33.5 bits (75), Expect = 0.51 Identities = 18/62 (29%), Positives = 33/62 (53%), Gaps = 2/62 (3%) Frame = +1 Query: 412 FSEKQEIGRGGFAVVYEG--SLLNVTVAVKKLTNLHMRDAPEVEYNREVECLMRVKHKNI 585 + + ++IG G + VVY+ + N T+A+KK+ + RE+ L ++H NI Sbjct: 4 YEKVEKIGEGTYGVVYKARDKVTNETIALKKIRLEQEDEGVPSTAIREISLLKEMQHSNI 63 Query: 586 VR 591 V+ Sbjct: 64 VK 65
>CDC2A_ANTMA (Q38772) Cell division control protein 2 homolog A (EC 2.7.11.22)| (EC 2.7.11.23) Length = 294 Score = 33.5 bits (75), Expect = 0.51 Identities = 19/62 (30%), Positives = 33/62 (53%), Gaps = 2/62 (3%) Frame = +1 Query: 412 FSEKQEIGRGGFAVVYEGS--LLNVTVAVKKLTNLHMRDAPEVEYNREVECLMRVKHKNI 585 + + ++IG G + VVY+ + N T+A+KK+ + RE+ L ++H NI Sbjct: 4 YEKVEKIGEGTYGVVYKARDRVTNETIALKKIRLEQEDEGVPSTAIREISLLKEMQHGNI 63 Query: 586 VR 591 VR Sbjct: 64 VR 65
>ATG1_YARLI (Q6C7U0) Serine/threonine-protein kinase ATG1 (EC 2.7.11.1)| (Autophagy-related protein 1) Length = 710 Score = 33.5 bits (75), Expect = 0.51 Identities = 18/61 (29%), Positives = 30/61 (49%), Gaps = 2/61 (3%) Frame = +1 Query: 427 EIGRGGFAVVYEGSLL--NVTVAVKKLTNLHMRDAPEVEYNREVECLMRVKHKNIVRFLG 600 E+GRG FA VY+G + VA+K + + E+ L ++KH ++V L Sbjct: 12 ELGRGSFATVYKGEHVASGSPVAIKSVLRAKLNRKLLENLGSEISILKQMKHPHVVELLD 71 Query: 601 Y 603 + Sbjct: 72 F 72
>CDK9_RAT (Q641Z4) Cell division protein kinase 9 (EC 2.7.11.22) (EC| 2.7.11.23) (Cyclin-dependent kinase 9) Length = 372 Score = 33.5 bits (75), Expect = 0.51 Identities = 20/73 (27%), Positives = 39/73 (53%), Gaps = 2/73 (2%) Frame = +1 Query: 394 DEITCGFSEKQEIGRGGFAVVYEGSLLNV--TVAVKKLTNLHMRDAPEVEYNREVECLMR 567 DE+T + + +IG+G F V++ VA+KK+ + ++ + RE++ L Sbjct: 14 DEVT-KYEKLAKIGQGTFGEVFKAKHRQTGQKVALKKVLMENEKEGFPITALREIKILQL 72 Query: 568 VKHKNIVRFLGYC 606 +KH+N+V + C Sbjct: 73 LKHENVVNLIEIC 85
>CDK9_MOUSE (Q99J95) Cell division protein kinase 9 (EC 2.7.11.22) (EC| 2.7.11.23) (Cyclin-dependent kinase 9) Length = 372 Score = 33.5 bits (75), Expect = 0.51 Identities = 20/73 (27%), Positives = 39/73 (53%), Gaps = 2/73 (2%) Frame = +1 Query: 394 DEITCGFSEKQEIGRGGFAVVYEGSLLNV--TVAVKKLTNLHMRDAPEVEYNREVECLMR 567 DE+T + + +IG+G F V++ VA+KK+ + ++ + RE++ L Sbjct: 14 DEVT-KYEKLAKIGQGTFGEVFKAKHRQTGQKVALKKVLMENEKEGFPITALREIKILQL 72 Query: 568 VKHKNIVRFLGYC 606 +KH+N+V + C Sbjct: 73 LKHENVVNLIEIC 85
>CDK9_BOVIN (Q5EAB2) Cell division protein kinase 9 (EC 2.7.11.22) (EC| 2.7.11.23) (Cyclin-dependent kinase 9) Length = 372 Score = 33.5 bits (75), Expect = 0.51 Identities = 20/73 (27%), Positives = 39/73 (53%), Gaps = 2/73 (2%) Frame = +1 Query: 394 DEITCGFSEKQEIGRGGFAVVYEGSLLNV--TVAVKKLTNLHMRDAPEVEYNREVECLMR 567 DE+T + + +IG+G F V++ VA+KK+ + ++ + RE++ L Sbjct: 14 DEVT-KYEKLAKIGQGTFGEVFKAKHRKTGQKVALKKVLMENEKEGFPITALREIKILQL 72 Query: 568 VKHKNIVRFLGYC 606 +KH+N+V + C Sbjct: 73 LKHENVVNLIEIC 85
>PHO85_CANGA (Q6FKD4) Negative regulator of the PHO system (EC 2.7.11.22)| (Serine/threonine-protein kinase PHO85) Length = 302 Score = 33.5 bits (75), Expect = 0.51 Identities = 20/62 (32%), Positives = 33/62 (53%), Gaps = 2/62 (3%) Frame = +1 Query: 412 FSEKQEIGRGGFAVVYEG--SLLNVTVAVKKLTNLHMRDAPEVEYNREVECLMRVKHKNI 585 F + +++G G +A VY+G V VA+K++ L + RE+ + +KH NI Sbjct: 6 FKQLEKLGNGTYATVYKGLNKSTGVYVALKEV-KLDSEEGTPSTAIREISLMKELKHDNI 64 Query: 586 VR 591 VR Sbjct: 65 VR 66
>JAK_DROME (Q24592) Tyrosine-protein kinase hopscotch (EC 2.7.10.2)| Length = 1177 Score = 33.5 bits (75), Expect = 0.51 Identities = 21/78 (26%), Positives = 37/78 (47%), Gaps = 7/78 (8%) Frame = +1 Query: 382 LSLLDEITCGFSEKQEIGRGGFAVVYEGSLL-------NVTVAVKKLTNLHMRDAPEVEY 540 + L E ++ + IGRG + VY+G L VA+K L + + ++ Sbjct: 882 IPLTSECRVIYNMENMIGRGHYGTVYKGHLEFNDKDQPREQVAIKMLNTMQV----STDF 937 Query: 541 NREVECLMRVKHKNIVRF 594 +RE+ + + H NIV+F Sbjct: 938 HREIGIMRTLSHPNIVKF 955
>CD2L7_CAEEL (P46551) Putative cell division cycle 2-related protein kinase 7| (EC 2.7.11.22) Length = 730 Score = 33.5 bits (75), Expect = 0.51 Identities = 19/64 (29%), Positives = 35/64 (54%), Gaps = 2/64 (3%) Frame = +1 Query: 427 EIGRGGFAVVYEG--SLLNVTVAVKKLTNLHMRDAPEVEYNREVECLMRVKHKNIVRFLG 600 +IG G + VY+ +L VA+K++ + ++ + RE++ L ++ HKNIVR + Sbjct: 316 QIGEGTYGQVYKAVNNLTGEQVALKRVRLENEKEGFPITAIREIKILRQLHHKNIVRLMD 375 Query: 601 YCAD 612 D Sbjct: 376 IVID 379
>ACK2_BOVIN (O02742) Activated CDC42 kinase 2 (EC 2.7.10.2) (ACK-2)| Length = 747 Score = 33.5 bits (75), Expect = 0.51 Identities = 27/82 (32%), Positives = 40/82 (48%), Gaps = 12/82 (14%) Frame = +1 Query: 391 LDEITCGFSEK-----QEIGRGGFAVVYEG-----SLLNVTVAVKKLTNLHMRDAPEV-- 534 L +TC EK +++G G F VV G S V+VAVK L + PE Sbjct: 114 LQSLTCLIGEKDLHLFEKLGDGSFGVVRRGEWDAPSGKTVSVAVKCLKP-DVLSQPEAMD 172 Query: 535 EYNREVECLMRVKHKNIVRFLG 600 ++ REV + + H+N++R G Sbjct: 173 DFIREVNAMHSLDHRNLIRLYG 194
>PCTK2_RAT (O35831) Serine/threonine-protein kinase PCTAIRE-2 (EC 2.7.11.22)| (PCTAIRE-motif protein kinase 2) Length = 523 Score = 33.5 bits (75), Expect = 0.51 Identities = 22/57 (38%), Positives = 31/57 (54%), Gaps = 2/57 (3%) Frame = +1 Query: 424 QEIGRGGFAVVYEG--SLLNVTVAVKKLTNLHMRDAPEVEYNREVECLMRVKHKNIV 588 +++G G +A VY+G L VA+K++ H AP REV L +KH NIV Sbjct: 196 EKLGEGTYATVYKGRSKLTENLVALKEIRLEHEEGAPCTAI-REVSLLKDLKHANIV 251
>PCTK2_MOUSE (Q8K0D0) Serine/threonine-protein kinase PCTAIRE-2 (EC 2.7.11.22)| (PCTAIRE-motif protein kinase 2) Length = 523 Score = 33.5 bits (75), Expect = 0.51 Identities = 22/57 (38%), Positives = 31/57 (54%), Gaps = 2/57 (3%) Frame = +1 Query: 424 QEIGRGGFAVVYEG--SLLNVTVAVKKLTNLHMRDAPEVEYNREVECLMRVKHKNIV 588 +++G G +A VY+G L VA+K++ H AP REV L +KH NIV Sbjct: 196 EKLGEGTYATVYKGRSKLTENLVALKEIRLEHEEGAPCTAI-REVSLLKDLKHANIV 251
>PCTK2_HUMAN (Q00537) Serine/threonine-protein kinase PCTAIRE-2 (EC 2.7.11.22)| (PCTAIRE-motif protein kinase 2) Length = 523 Score = 33.5 bits (75), Expect = 0.51 Identities = 22/57 (38%), Positives = 31/57 (54%), Gaps = 2/57 (3%) Frame = +1 Query: 424 QEIGRGGFAVVYEG--SLLNVTVAVKKLTNLHMRDAPEVEYNREVECLMRVKHKNIV 588 +++G G +A VY+G L VA+K++ H AP REV L +KH NIV Sbjct: 196 EKLGEGTYATVYKGRSKLTENLVALKEIRLEHEEGAPCTAI-REVSLLKDLKHANIV 251
>M3KSL_DROME (Q95UN8) Mitogen-activated protein kinase kinase kinase (EC| 2.7.11.25) (Mixed lineage kinase) (dMLK) (Protein slipper) Length = 1161 Score = 33.5 bits (75), Expect = 0.51 Identities = 21/67 (31%), Positives = 30/67 (44%), Gaps = 2/67 (2%) Frame = +1 Query: 421 KQEIGRGGFAVVYEGSLLNVTVAVKKLTNLHMRDAPEVEYN--REVECLMRVKHKNIVRF 594 K+ IG GGF V+ G VA+K D + N +E + +KH+NI Sbjct: 145 KEVIGSGGFCKVHRGYYDGEEVAIKIAHQTGEDDMQRMRDNVLQEAKLFWALKHENIAAL 204 Query: 595 LGYCADT 615 G C +T Sbjct: 205 RGVCLNT 211
>KCC2_SCHPO (O42844) Calcium/calmodulin-dependent protein kinase type II (EC| 2.7.11.17) (CAM kinase II) Length = 504 Score = 33.5 bits (75), Expect = 0.51 Identities = 19/62 (30%), Positives = 30/62 (48%), Gaps = 2/62 (3%) Frame = +1 Query: 424 QEIGRGGFAVVYEGSLLNVT--VAVKKLTNLHMRDAPEVEYNREVECLMRVKHKNIVRFL 597 + +G G F+ VY+ ++ VAVK + M +EV + RVKHKN+V Sbjct: 69 ENLGDGAFSQVYKAYSIDRKEHVAVKVIRKYEMNKKQRQGVFKEVNIMRRVKHKNVVNLF 128 Query: 598 GY 603 + Sbjct: 129 DF 130
>TAOK3_MOUSE (Q8BYC6) Serine/threonine-protein kinase TAO3 (EC 2.7.11.1)| (Thousand and one amino acid protein 3) Length = 898 Score = 33.5 bits (75), Expect = 0.51 Identities = 24/82 (29%), Positives = 40/82 (48%), Gaps = 3/82 (3%) Frame = +1 Query: 364 EPKALPLSLLDEITCGFSEKQEIGRGGFAVVY--EGSLLNVTVAVKKLTNLHMRDAPE-V 534 +P+ L D+ F + EIG G F VY + N VAVKK++ + + Sbjct: 8 DPEIADLFFKDDPEELFIDLHEIGHGSFGAVYFATNAHTNEVVAVKKMSYSGKQTHEKWQ 67 Query: 535 EYNREVECLMRVKHKNIVRFLG 600 + +EV+ L ++KH N + + G Sbjct: 68 DILKEVKFLQQLKHPNTIEYKG 89
>PHO85_ASHGO (Q751E8) Negative regulator of the PHO system (EC 2.7.11.22)| (Serine/threonine-protein kinase PHO85) Length = 303 Score = 33.5 bits (75), Expect = 0.51 Identities = 22/64 (34%), Positives = 35/64 (54%), Gaps = 4/64 (6%) Frame = +1 Query: 412 FSEKQEIGRGGFAVVYEGSLLNVT----VAVKKLTNLHMRDAPEVEYNREVECLMRVKHK 579 F + + +G G +A VY+G LN T VA+K++ L + RE+ + +KH+ Sbjct: 9 FKQLERLGNGTYATVYKG--LNKTTGLYVALKEV-KLDSEEGTPSTAIREISLMKELKHE 65 Query: 580 NIVR 591 NIVR Sbjct: 66 NIVR 69
>BLVR_BOVIN (Q03368) Bovine leukemia virus cell receptor precursor (BLV-R)| (BLVPCP1) Length = 843 Score = 33.5 bits (75), Expect = 0.51 Identities = 23/57 (40%), Positives = 26/57 (45%), Gaps = 8/57 (14%) Frame = +3 Query: 33 PPGKESHRDTLG--IASGRLKAAVIS-----AAEGGGVRRT-PWPGCAAAVLSEWWR 179 P G S T+G +A R V S +AEG R PWP C AA EWWR Sbjct: 705 PRGTSSPGHTMGQSLAGCRPSHPVCSTTVSCSAEGSAQRGPGPWPPCPAACCGEWWR 761
>ACK1_HUMAN (Q07912) Activated CDC42 kinase 1 (EC 2.7.10.2) (ACK-1) (Tyrosine| kinase non-receptor protein 2) Length = 1036 Score = 33.5 bits (75), Expect = 0.51 Identities = 27/82 (32%), Positives = 40/82 (48%), Gaps = 12/82 (14%) Frame = +1 Query: 391 LDEITCGFSEK-----QEIGRGGFAVVYEG-----SLLNVTVAVKKLTNLHMRDAPEV-- 534 L +TC EK +++G G F VV G S V+VAVK L + PE Sbjct: 114 LQSLTCLIGEKDLRLLEKLGDGSFGVVRRGEWDAPSGKTVSVAVKCLKP-DVLSQPEAMD 172 Query: 535 EYNREVECLMRVKHKNIVRFLG 600 ++ REV + + H+N++R G Sbjct: 173 DFIREVNAMHSLDHRNLIRLYG 194
>CDK9_CAEEL (Q9TVL3) Probable cell division protein kinase 9 (EC 2.7.11.22) (EC| 2.7.11.23) (Cyclin-dependent kinase 9) Length = 478 Score = 33.5 bits (75), Expect = 0.51 Identities = 19/68 (27%), Positives = 36/68 (52%), Gaps = 2/68 (2%) Frame = +1 Query: 412 FSEKQEIGRGGFAVVYEGSLLNV--TVAVKKLTNLHMRDAPEVEYNREVECLMRVKHKNI 585 + + +IG+G F V++ N VA+KK+ + ++ + REV+ L ++KH NI Sbjct: 85 YEKLNKIGQGTFGEVFKARCKNTGRMVALKKILMENEKEGFPITALREVKMLEQLKHPNI 144 Query: 586 VRFLGYCA 609 + C+ Sbjct: 145 TDLIEVCS 152
>M3K12_RAT (Q63796) Mitogen-activated protein kinase kinase kinase 12 (EC| 2.7.11.25) (Mixed lineage kinase) (Leucine-zipper protein kinase) (ZPK) (Dual leucine zipper bearing kinase) (DLK) (MAPK-upstream kinase) (MUK) Length = 888 Score = 33.1 bits (74), Expect = 0.66 Identities = 20/61 (32%), Positives = 29/61 (47%) Frame = +1 Query: 424 QEIGRGGFAVVYEGSLLNVTVAVKKLTNLHMRDAPEVEYNREVECLMRVKHKNIVRFLGY 603 Q +G G V+ G VAVKK+ +L D ++ L ++KH NI+ F G Sbjct: 162 QWVGSGAQGAVFLGRFHGEEVAVKKVRDLKETD---------IKHLRKLKHPNIITFKGV 212 Query: 604 C 606 C Sbjct: 213 C 213
>M3K12_MOUSE (Q60700) Mitogen-activated protein kinase kinase kinase 12 (EC| 2.7.11.25) (Mixed lineage kinase) (Leucine-zipper protein kinase) (ZPK) (Dual leucine zipper bearing kinase) (DLK) (MAPK-upstream kinase) (MUK) Length = 888 Score = 33.1 bits (74), Expect = 0.66 Identities = 20/61 (32%), Positives = 29/61 (47%) Frame = +1 Query: 424 QEIGRGGFAVVYEGSLLNVTVAVKKLTNLHMRDAPEVEYNREVECLMRVKHKNIVRFLGY 603 Q +G G V+ G VAVKK+ +L D ++ L ++KH NI+ F G Sbjct: 162 QWVGSGAQGAVFLGRFHGEEVAVKKVRDLKETD---------IKHLRKLKHPNIITFKGV 212 Query: 604 C 606 C Sbjct: 213 C 213
>M3K12_HUMAN (Q12852) Mitogen-activated protein kinase kinase kinase 12 (EC| 2.7.11.25) (Mixed lineage kinase) (Leucine-zipper protein kinase) (ZPK) (Dual leucine zipper bearing kinase) (DLK) (MAPK-upstream kinase) (MUK) Length = 859 Score = 33.1 bits (74), Expect = 0.66 Identities = 20/61 (32%), Positives = 29/61 (47%) Frame = +1 Query: 424 QEIGRGGFAVVYEGSLLNVTVAVKKLTNLHMRDAPEVEYNREVECLMRVKHKNIVRFLGY 603 Q +G G V+ G VAVKK+ +L D ++ L ++KH NI+ F G Sbjct: 129 QWVGSGAQGAVFLGRFHGEEVAVKKVRDLKETD---------IKHLRKLKHPNIITFKGV 179 Query: 604 C 606 C Sbjct: 180 C 180
>PHO85_YARLI (Q6C7U8) Negative regulator of the PHO system (EC 2.7.11.22)| (Serine/threonine-protein kinase PHO85) Length = 294 Score = 33.1 bits (74), Expect = 0.66 Identities = 19/61 (31%), Positives = 33/61 (54%), Gaps = 2/61 (3%) Frame = +1 Query: 412 FSEKQEIGRGGFAVVYEG--SLLNVTVAVKKLTNLHMRDAPEVEYNREVECLMRVKHKNI 585 F + +++G G +A VY+G VA+K++ NL + RE+ + +KH+NI Sbjct: 7 FQQLEKLGEGTYATVYKGRNRTTGQLVALKEI-NLDSEEGTPSTAIREISLMKELKHENI 65 Query: 586 V 588 V Sbjct: 66 V 66
>CDC2_VIGUN (P52389) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34cdc2) Length = 294 Score = 33.1 bits (74), Expect = 0.66 Identities = 18/62 (29%), Positives = 34/62 (54%), Gaps = 2/62 (3%) Frame = +1 Query: 412 FSEKQEIGRGGFAVVYEGS--LLNVTVAVKKLTNLHMRDAPEVEYNREVECLMRVKHKNI 585 + + ++IG G + VVY+ + + T+A+KK+ + RE+ L ++H+NI Sbjct: 4 YEKVEKIGEGTYGVVYKARDRVTDETIALKKIRLEQEDEGVPSTAIREISLLKEMQHRNI 63 Query: 586 VR 591 VR Sbjct: 64 VR 65
>LTK_HUMAN (P29376) Leukocyte tyrosine kinase receptor precursor (EC 2.7.10.1)| (Protein tyrosine kinase 1) Length = 864 Score = 33.1 bits (74), Expect = 0.66 Identities = 23/87 (26%), Positives = 41/87 (47%), Gaps = 7/87 (8%) Frame = +1 Query: 361 AEPKALPLSLLDEITCGFSEKQEIGRGGFAVVYEGSLLNVT-------VAVKKLTNLHMR 519 A+ LP + + + + +G G F VYEG ++ + VA+K L L Sbjct: 493 AQSWPLPPGVTEVSPANVTLLRALGHGAFGEVYEGLVIGLPGDSSPLQVAIKTLPEL-CS 551 Query: 520 DAPEVEYNREVECLMRVKHKNIVRFLG 600 E+++ E + + +H+NIVR +G Sbjct: 552 PQDELDFLMEALIISKFRHQNIVRCVG 578
>PCTK3_RAT (O35832) Serine/threonine-protein kinase PCTAIRE-3 (EC 2.7.11.22)| (PCTAIRE-motif protein kinase 3) Length = 451 Score = 33.1 bits (74), Expect = 0.66 Identities = 33/109 (30%), Positives = 52/109 (47%), Gaps = 10/109 (9%) Frame = +1 Query: 292 LQMDIQMIPSTVEDLESMVIDESAEPKALPL----SLLDEITCG----FSEKQEIGRGGF 447 L MDI++ E L+ + ++ PK L + L +I G + + ++G G + Sbjct: 76 LPMDIRL---PQEFLQKLQLENPGLPKPLTRMSRRASLSDIGFGKLETYVKLDKLGEGTY 132 Query: 448 AVVYEG--SLLNVTVAVKKLTNLHMRDAPEVEYNREVECLMRVKHKNIV 588 A V++G L VA+K++ H AP REV L +KH NIV Sbjct: 133 ATVFKGRSKLTENLVALKEIRLEHEEGAPCTAI-REVSLLKDLKHANIV 180
>PCTK3_MOUSE (Q04899) Serine/threonine-protein kinase PCTAIRE-3 (EC 2.7.11.22)| (PCTAIRE-motif protein kinase 3) Length = 451 Score = 33.1 bits (74), Expect = 0.66 Identities = 33/109 (30%), Positives = 52/109 (47%), Gaps = 10/109 (9%) Frame = +1 Query: 292 LQMDIQMIPSTVEDLESMVIDESAEPKALPL----SLLDEITCG----FSEKQEIGRGGF 447 L MDI++ E L+ + ++ PK L + L +I G + + ++G G + Sbjct: 76 LPMDIRL---PQEFLQKLQLENPGLPKPLTRMSRRASLSDIGFGKLETYVKLDKLGEGTY 132 Query: 448 AVVYEG--SLLNVTVAVKKLTNLHMRDAPEVEYNREVECLMRVKHKNIV 588 A V++G L VA+K++ H AP REV L +KH NIV Sbjct: 133 ATVFKGRSKLTENLVALKEIRLEHEEGAPCTAI-REVSLLKDLKHANIV 180
>ATG1_CANAL (Q5A649) Serine/threonine-protein kinase ATG1 (EC 2.7.11.1)| (Autophagy-related protein 1) Length = 834 Score = 33.1 bits (74), Expect = 0.66 Identities = 21/62 (33%), Positives = 33/62 (53%), Gaps = 3/62 (4%) Frame = +1 Query: 427 EIGRGGFAVVYE--GSLLNVTVAVKKLTNLHMRDAPEVE-YNREVECLMRVKHKNIVRFL 597 EIG+G FA VY+ + N VA+K + ++ +E E++ L +KH +IV L Sbjct: 63 EIGKGSFATVYKCIDTTNNKAVAIKSVYRSKLKSKKLLENLEIEIQILKSMKHPHIVGLL 122 Query: 598 GY 603 Y Sbjct: 123 DY 124
>M3K13_PONPY (Q5R8X7) Mitogen-activated protein kinase kinase kinase 13 (EC| 2.7.11.25) Length = 966 Score = 33.1 bits (74), Expect = 0.66 Identities = 20/64 (31%), Positives = 30/64 (46%) Frame = +1 Query: 415 SEKQEIGRGGFAVVYEGSLLNVTVAVKKLTNLHMRDAPEVEYNREVECLMRVKHKNIVRF 594 SE Q +G G V+ G VA+KK+ + D ++ L ++KH NI+ F Sbjct: 169 SELQWLGSGAQGAVFLGKFRAEEVAIKKVREQNETD---------IKHLRKLKHPNIIAF 219 Query: 595 LGYC 606 G C Sbjct: 220 KGVC 223
>M3K13_HUMAN (O43283) Mitogen-activated protein kinase kinase kinase 13 (EC| 2.7.11.25) (Mixed lineage kinase) (MLK) (Leucine zipper-bearing kinase) Length = 966 Score = 33.1 bits (74), Expect = 0.66 Identities = 20/64 (31%), Positives = 30/64 (46%) Frame = +1 Query: 415 SEKQEIGRGGFAVVYEGSLLNVTVAVKKLTNLHMRDAPEVEYNREVECLMRVKHKNIVRF 594 SE Q +G G V+ G VA+KK+ + D ++ L ++KH NI+ F Sbjct: 169 SELQWLGSGAQGAVFLGKFRAEEVAIKKVREQNETD---------IKHLRKLKHPNIIAF 219 Query: 595 LGYC 606 G C Sbjct: 220 KGVC 223
>CDC2_CAEEL (P34556) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) Length = 332 Score = 33.1 bits (74), Expect = 0.66 Identities = 19/61 (31%), Positives = 32/61 (52%), Gaps = 2/61 (3%) Frame = +1 Query: 412 FSEKQEIGRGGFAVVYEGS--LLNVTVAVKKLTNLHMRDAPEVEYNREVECLMRVKHKNI 585 F++ ++IG G + VVY+G N VA+KK+ + RE+ L ++H N+ Sbjct: 22 FTKLEKIGEGTYGVVYKGKNRRTNAMVAMKKIRLESEDEGVPSTAVREISLLKELQHPNV 81 Query: 586 V 588 V Sbjct: 82 V 82
>CDC2_MAIZE (P23111) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34cdc2) Length = 294 Score = 32.7 bits (73), Expect = 0.87 Identities = 19/62 (30%), Positives = 31/62 (50%), Gaps = 2/62 (3%) Frame = +1 Query: 412 FSEKQEIGRGGFAVVYEG--SLLNVTVAVKKLTNLHMRDAPEVEYNREVECLMRVKHKNI 585 + + ++IG G + VVY+ N T+A+KK+ + RE+ L + H NI Sbjct: 4 YEKVEKIGEGTYGVVYKALDKATNETIALKKIRLEQEDEGVPSTAIREISLLKEMNHGNI 63 Query: 586 VR 591 VR Sbjct: 64 VR 65
>PUF4_YEAST (P25339) Protein PUF4| Length = 888 Score = 32.7 bits (73), Expect = 0.87 Identities = 16/40 (40%), Positives = 21/40 (52%) Frame = -3 Query: 559 SIQPLGCTPPQAHHAYAGWSTSSPPPSHSEGFPHKLPQIH 440 S+QP PPQ + W S+PPP ++ PH L Q H Sbjct: 424 SMQPFHILPPQQNTPPPPWLYSTPPPFNAMVPPHLLAQNH 463
>PFTK1_MOUSE (O35495) Serine/threonine-protein kinase PFTAIRE-1 (EC 2.7.11.22)| Length = 469 Score = 32.7 bits (73), Expect = 0.87 Identities = 18/60 (30%), Positives = 30/60 (50%), Gaps = 1/60 (1%) Frame = +1 Query: 412 FSEKQEIGRGGFAVVYEG-SLLNVTVAVKKLTNLHMRDAPEVEYNREVECLMRVKHKNIV 588 + + +++G G +A VY+G S +N + K+ L + RE L +KH NIV Sbjct: 135 YEKLEKLGEGSYATVYKGKSKVNGKLVALKVIRLQEEEGTPFTAIREASLLKGLKHANIV 194
>PFTK1_HUMAN (O94921) Serine/threonine-protein kinase PFTAIRE-1 (EC 2.7.11.22)| Length = 469 Score = 32.7 bits (73), Expect = 0.87 Identities = 18/60 (30%), Positives = 30/60 (50%), Gaps = 1/60 (1%) Frame = +1 Query: 412 FSEKQEIGRGGFAVVYEG-SLLNVTVAVKKLTNLHMRDAPEVEYNREVECLMRVKHKNIV 588 + + +++G G +A VY+G S +N + K+ L + RE L +KH NIV Sbjct: 135 YEKLEKLGEGSYATVYKGKSKVNGKLVALKVIRLQEEEGTPFTAIREASLLKGLKHANIV 194
>NEK1_MOUSE (P51954) Serine/threonine-protein kinase Nek1 (EC 2.7.11.1)| (NimA-related protein kinase 1) Length = 1203 Score = 32.7 bits (73), Expect = 0.87 Identities = 20/59 (33%), Positives = 30/59 (50%), Gaps = 2/59 (3%) Frame = +1 Query: 424 QEIGRGGF--AVVYEGSLLNVTVAVKKLTNLHMRDAPEVEYNREVECLMRVKHKNIVRF 594 Q+IG G F AV+ + + +K++ M D E REV L +KH NIV++ Sbjct: 8 QKIGEGSFGKAVLVKSTEDGRHYVIKEINISRMSDKERQESRREVAVLANMKHPNIVQY 66 Database: uniprot_sprot.fasta Posted date: May 25, 2006 5:36 PM Number of letters in database: 80,573,946 Number of sequences in database: 219,361 Lambda K H 0.318 0.135 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 91,521,467 Number of Sequences: 219361 Number of extensions: 2003949 Number of successful extensions: 8240 Number of sequences better than 10.0: 479 Number of HSP's better than 10.0 without gapping: 7457 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 8088 length of database: 80,573,946 effective HSP length: 107 effective length of database: 57,102,319 effective search space used: 5538924943 frameshift window, decay const: 50, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
