ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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| Clone Name | baalp07 |
|---|---|
| Clone Library Name | barley_pub |
>SRK6_BRAOE (Q09092) Putative serine/threonine-protein kinase receptor| precursor (EC 2.7.11.1) (S-receptor kinase) (SRK) Length = 849 Score = 117 bits (293), Expect = 3e-26 Identities = 57/95 (60%), Positives = 74/95 (77%) Frame = +1 Query: 346 TLRVATDNFDERNKLGEGGFGVVYKGILPDNEEIAVKRLSQSSRQGIEELKNELVLVAKL 525 T+ AT+NF NKLG+GGFG+VYKG L D +EIAVKRLS++S QG +E NE+ L+A+L Sbjct: 520 TVVKATENFSSCNKLGQGGFGIVYKGRLLDGKEIAVKRLSKTSVQGTDEFMNEVTLIARL 579 Query: 526 QHKNLVRLLGVCLEEQEKLLAYEYMPNKSLDTILF 630 QH NLV++LG C+E EK+L YEY+ N SLD+ LF Sbjct: 580 QHINLVQVLGCCIEGDEKMLIYEYLENLSLDSYLF 614
>TMK1_ARATH (P43298) Putative receptor protein kinase TMK1 precursor (EC| 2.7.11.1) Length = 942 Score = 96.3 bits (238), Expect = 7e-20 Identities = 49/97 (50%), Positives = 65/97 (67%), Gaps = 2/97 (2%) Frame = +1 Query: 349 LRVATDNFDERNKLGEGGFGVVYKGILPDNEEIAVKRLSQS--SRQGIEELKNELVLVAK 522 LR T+NF N LG GGFGVVYKG L D +IAVKR+ + +G E K+E+ ++ K Sbjct: 581 LRSVTNNFSSDNILGSGGFGVVYKGELHDGTKIAVKRMENGVIAGKGFAEFKSEIAVLTK 640 Query: 523 LQHKNLVRLLGVCLEEQEKLLAYEYMPNKSLDTILFD 633 ++H++LV LLG CL+ EKLL YEYMP +L LF+ Sbjct: 641 VRHRHLVTLLGYCLDGNEKLLVYEYMPQGTLSRHLFE 677
>EXS_ARATH (Q9LYN8) Leucine-rich repeat receptor protein kinase EXS precursor| (EC 2.7.11.1) (Extra sporogenous cells protein) (EXCESS MICROSPOROCYTES1 protein) Length = 1192 Score = 94.7 bits (234), Expect = 2e-19 Identities = 45/87 (51%), Positives = 60/87 (68%) Frame = +1 Query: 358 ATDNFDERNKLGEGGFGVVYKGILPDNEEIAVKRLSQSSRQGIEELKNELVLVAKLQHKN 537 ATD+F ++N +G+GGFG VYK LP + +AVK+LS++ QG E E+ + K++H N Sbjct: 913 ATDHFSKKNIIGDGGFGTVYKACLPGEKTVAVKKLSEAKTQGNREFMAEMETLGKVKHPN 972 Query: 538 LVRLLGVCLEEQEKLLAYEYMPNKSLD 618 LV LLG C +EKLL YEYM N SLD Sbjct: 973 LVSLLGYCSFSEEKLLVYEYMVNGSLD 999
>BAK1_ARATH (Q94F62) BRASSINOSTEROID INSENSITIVE 1-associated receptor kinase 1| precursor (EC 2.7.11.1) (BRI1-associated receptor kinase 1) (Somatic embryogenesis receptor-like kinase 3) Length = 615 Score = 85.9 bits (211), Expect = 9e-17 Identities = 44/94 (46%), Positives = 61/94 (64%), Gaps = 1/94 (1%) Frame = +1 Query: 349 LRVATDNFDERNKLGEGGFGVVYKGILPDNEEIAVKRLSQSSRQGIE-ELKNELVLVAKL 525 L+VA+DNF +N LG GGFG VYKG L D +AVKRL + QG E + + E+ +++ Sbjct: 282 LQVASDNFSNKNILGRGGFGKVYKGRLADGTLVAVKRLKEERTQGGELQFQTEVEMISMA 341 Query: 526 QHKNLVRLLGVCLEEQEKLLAYEYMPNKSLDTIL 627 H+NL+RL G C+ E+LL Y YM N S+ + L Sbjct: 342 VHRNLLRLRGFCMTPTERLLVYPYMANGSVASCL 375
>PSKR_DAUCA (Q8LPB4) Phytosulfokine receptor precursor (EC 2.7.11.1)| (Phytosulfokine LRR receptor kinase) Length = 1021 Score = 84.3 bits (207), Expect = 3e-16 Identities = 41/87 (47%), Positives = 58/87 (66%) Frame = +1 Query: 358 ATDNFDERNKLGEGGFGVVYKGILPDNEEIAVKRLSQSSRQGIEELKNELVLVAKLQHKN 537 +T +F++ N +G GGFG+VYK LPD ++A+KRLS + Q E + E+ +++ QH N Sbjct: 739 STSSFNQANIIGCGGFGLVYKATLPDGTKVAIKRLSGDTGQMDREFQAEVETLSRAQHPN 798 Query: 538 LVRLLGVCLEEQEKLLAYEYMPNKSLD 618 LV LLG C + +KLL Y YM N SLD Sbjct: 799 LVHLLGYCNYKNDKLLIYSYMDNGSLD 825
>NORK_PEA (Q8LKZ1) Nodulation receptor kinase precursor (EC 2.7.11.1)| Length = 924 Score = 84.0 bits (206), Expect = 4e-16 Identities = 42/89 (47%), Positives = 60/89 (67%) Frame = +1 Query: 349 LRVATDNFDERNKLGEGGFGVVYKGILPDNEEIAVKRLSQSSRQGIEELKNELVLVAKLQ 528 + +AT+ + + +GEGGFG VY+G L D +E+AVK S +S QG E NEL L++ +Q Sbjct: 590 IELATEKY--KTLIGEGGFGSVYRGTLDDGQEVAVKVRSATSTQGTREFDNELNLLSAIQ 647 Query: 529 HKNLVRLLGVCLEEQEKLLAYEYMPNKSL 615 H+NLV LLG C E +++L Y +M N SL Sbjct: 648 HENLVPLLGYCNEYDQQILVYPFMSNGSL 676
>BRL3_ARATH (Q9LJF3) Serine/threonine-protein kinase BRI1-like 3 precursor (EC| 2.7.11.1) (BRASSINOSTEROID INSENSITIVE 1-like protein 3) Length = 1164 Score = 83.2 bits (204), Expect = 6e-16 Identities = 41/92 (44%), Positives = 58/92 (63%) Frame = +1 Query: 358 ATDNFDERNKLGEGGFGVVYKGILPDNEEIAVKRLSQSSRQGIEELKNELVLVAKLQHKN 537 AT+ F + +G GGFG VYK L D +A+K+L Q + QG E E+ + K++H+N Sbjct: 854 ATNGFSADSMIGSGGFGDVYKAKLADGSVVAIKKLIQVTGQGDREFMAEMETIGKIKHRN 913 Query: 538 LVRLLGVCLEEQEKLLAYEYMPNKSLDTILFD 633 LV LLG C +E+LL YEYM SL+T+L + Sbjct: 914 LVPLLGYCKIGEERLLVYEYMKYGSLETVLHE 945
>NORK_MEDTR (Q8L4H4) Nodulation receptor kinase precursor (EC 2.7.11.1) (Does| not make infections protein 2) (Symbiosis receptor-like kinase) (MtSYMRK) Length = 925 Score = 83.2 bits (204), Expect = 6e-16 Identities = 42/86 (48%), Positives = 58/86 (67%) Frame = +1 Query: 358 ATDNFDERNKLGEGGFGVVYKGILPDNEEIAVKRLSQSSRQGIEELKNELVLVAKLQHKN 537 AT+ + + +GEGGFG VY+G L D +E+AVK S +S QG E NEL L++ +QH+N Sbjct: 594 ATEQY--KTLIGEGGFGSVYRGTLDDGQEVAVKVRSSTSTQGTREFDNELNLLSAIQHEN 651 Query: 538 LVRLLGVCLEEQEKLLAYEYMPNKSL 615 LV LLG C E +++L Y +M N SL Sbjct: 652 LVPLLGYCNEYDQQILVYPFMSNGSL 677
>CX32_ARATH (P27450) Probable serine/threonine-protein kinase Cx32, chloroplast| precursor (EC 2.7.11.1) Length = 419 Score = 83.2 bits (204), Expect = 6e-16 Identities = 45/104 (43%), Positives = 64/104 (61%), Gaps = 10/104 (9%) Frame = +1 Query: 349 LRVATDNFDERNKLGEGGFGVVYKG------ILPDNEE----IAVKRLSQSSRQGIEELK 498 L+ AT NF + LG+GGFG VY+G + P +A+KRL+ S QG E + Sbjct: 79 LKTATKNFKPDSMLGQGGFGKVYRGWVDATTLAPSRVGSGMIVAIKRLNSESVQGFAEWR 138 Query: 499 NELVLVAKLQHKNLVRLLGVCLEEQEKLLAYEYMPNKSLDTILF 630 +E+ + L H+NLV+LLG C E++E LL YE+MP SL++ LF Sbjct: 139 SEVNFLGMLSHRNLVKLLGYCREDKELLLVYEFMPKGSLESHLF 182
>BRI1_ARATH (O22476) BRASSINOSTEROID INSENSITIVE 1 precursor (EC 2.7.11.1)| (AtBRI1) (Brassinosteroid LRR receptor kinase) Length = 1196 Score = 82.4 bits (202), Expect = 1e-15 Identities = 41/92 (44%), Positives = 56/92 (60%) Frame = +1 Query: 358 ATDNFDERNKLGEGGFGVVYKGILPDNEEIAVKRLSQSSRQGIEELKNELVLVAKLQHKN 537 AT+ F + +G GGFG VYK IL D +A+K+L S QG E E+ + K++H+N Sbjct: 879 ATNGFHNDSLIGSGGFGDVYKAILKDGSAVAIKKLIHVSGQGDREFMAEMETIGKIKHRN 938 Query: 538 LVRLLGVCLEEQEKLLAYEYMPNKSLDTILFD 633 LV LLG C E+LL YE+M SL+ +L D Sbjct: 939 LVPLLGYCKVGDERLLVYEFMKYGSLEDVLHD 970
>PSKR_ARATH (Q9ZVR7) Putative phytosulfokine receptor precursor (EC 2.7.11.1)| (Phytosulfokine LRR receptor kinase) Length = 1008 Score = 82.0 bits (201), Expect = 1e-15 Identities = 39/87 (44%), Positives = 58/87 (66%) Frame = +1 Query: 358 ATDNFDERNKLGEGGFGVVYKGILPDNEEIAVKRLSQSSRQGIEELKNELVLVAKLQHKN 537 +T++FD+ N +G GGFG+VYK LPD +++A+K+LS Q E + E+ +++ QH N Sbjct: 730 STNSFDQANIIGCGGFGMVYKATLPDGKKVAIKKLSGDCGQIEREFEAEVETLSRAQHPN 789 Query: 538 LVRLLGVCLEEQEKLLAYEYMPNKSLD 618 LV L G C + ++LL Y YM N SLD Sbjct: 790 LVLLRGFCFYKNDRLLIYSYMENGSLD 816
>BRI1_LYCPE (Q8L899) Systemin receptor SR160 precursor (EC 2.7.11.1)| (Brassinosteroid LRR receptor kinase) Length = 1207 Score = 81.3 bits (199), Expect = 2e-15 Identities = 41/92 (44%), Positives = 56/92 (60%) Frame = +1 Query: 358 ATDNFDERNKLGEGGFGVVYKGILPDNEEIAVKRLSQSSRQGIEELKNELVLVAKLQHKN 537 AT+ F + +G GGFG VYK L D +A+K+L S QG E E+ + K++H+N Sbjct: 884 ATNGFHNDSLVGSGGFGDVYKAQLKDGSVVAIKKLIHVSGQGDREFTAEMETIGKIKHRN 943 Query: 538 LVRLLGVCLEEQEKLLAYEYMPNKSLDTILFD 633 LV LLG C +E+LL YEYM SL+ +L D Sbjct: 944 LVPLLGYCKVGEERLLVYEYMKYGSLEDVLHD 975
>BRI1_LYCES (Q8GUQ5) Brassinosteroid LRR receptor kinase precursor (EC 2.7.11.1)| (tBRI1) (Altered brassinolide sensitivity 1) (Systemin receptor SR160) Length = 1207 Score = 81.3 bits (199), Expect = 2e-15 Identities = 41/92 (44%), Positives = 56/92 (60%) Frame = +1 Query: 358 ATDNFDERNKLGEGGFGVVYKGILPDNEEIAVKRLSQSSRQGIEELKNELVLVAKLQHKN 537 AT+ F + +G GGFG VYK L D +A+K+L S QG E E+ + K++H+N Sbjct: 884 ATNGFHNDSLVGSGGFGDVYKAQLKDGSVVAIKKLIHVSGQGDREFTAEMETIGKIKHRN 943 Query: 538 LVRLLGVCLEEQEKLLAYEYMPNKSLDTILFD 633 LV LLG C +E+LL YEYM SL+ +L D Sbjct: 944 LVPLLGYCKVGEERLLVYEYMKYGSLEDVLHD 975
>BRL1_ARATH (Q9ZWC8) Serine/threonine-protein kinase BRI1-like 1 precursor (EC| 2.7.11.1) (BRASSINOSTEROID INSENSITIVE 1-like protein 1) Length = 1166 Score = 81.3 bits (199), Expect = 2e-15 Identities = 40/92 (43%), Positives = 57/92 (61%) Frame = +1 Query: 358 ATDNFDERNKLGEGGFGVVYKGILPDNEEIAVKRLSQSSRQGIEELKNELVLVAKLQHKN 537 AT+ F +G GGFG VYK L D +A+K+L + + QG E E+ + K++H+N Sbjct: 855 ATNGFSAETMVGSGGFGEVYKAQLRDGSVVAIKKLIRITGQGDREFMAEMETIGKIKHRN 914 Query: 538 LVRLLGVCLEEQEKLLAYEYMPNKSLDTILFD 633 LV LLG C +E+LL YEYM SL+T+L + Sbjct: 915 LVPLLGYCKVGEERLLVYEYMKWGSLETVLHE 946
>APK1B_ARATH (P46573) Protein kinase APK1B, chloroplast precursor (EC 2.7.11.1)| Length = 412 Score = 80.5 bits (197), Expect = 4e-15 Identities = 44/104 (42%), Positives = 62/104 (59%), Gaps = 10/104 (9%) Frame = +1 Query: 349 LRVATDNFDERNKLGEGGFGVVYKGILPDNE----------EIAVKRLSQSSRQGIEELK 498 L+ AT NF + LGEGGFG V+KG + + IAVK+L+Q QG +E Sbjct: 62 LKAATRNFRPDSVLGEGGFGSVFKGWIDEQTLTASKPGTGVVIAVKKLNQDGWQGHQEWL 121 Query: 499 NELVLVAKLQHKNLVRLLGVCLEEQEKLLAYEYMPNKSLDTILF 630 E+ + + H NLV+L+G CLE++ +LL YE+MP SL+ LF Sbjct: 122 AEVNYLGQFSHPNLVKLIGYCLEDEHRLLVYEFMPRGSLENHLF 165
>NAK_ARATH (P43293) Probable serine/threonine-protein kinase NAK (EC 2.7.11.1)| Length = 389 Score = 80.1 bits (196), Expect = 5e-15 Identities = 45/104 (43%), Positives = 62/104 (59%), Gaps = 10/104 (9%) Frame = +1 Query: 349 LRVATDNFDERNKLGEGGFGVVYKGILPDNE----------EIAVKRLSQSSRQGIEELK 498 L+ AT NF + +GEGGFG V+KG + ++ IAVKRL+Q QG E Sbjct: 61 LKSATRNFRPDSVVGEGGFGCVFKGWIDESSLAPSKPGTGIVIAVKRLNQEGFQGHREWL 120 Query: 499 NELVLVAKLQHKNLVRLLGVCLEEQEKLLAYEYMPNKSLDTILF 630 E+ + +L H NLV+L+G CLEE+ +LL YE+M SL+ LF Sbjct: 121 AEINYLGQLDHPNLVKLIGYCLEEEHRLLVYEFMTRGSLENHLF 164
>APK1A_ARATH (Q06548) Protein kinase APK1A, chloroplast precursor (EC 2.7.11.1)| Length = 410 Score = 79.7 bits (195), Expect = 7e-15 Identities = 43/104 (41%), Positives = 63/104 (60%), Gaps = 10/104 (9%) Frame = +1 Query: 349 LRVATDNFDERNKLGEGGFGVVYKGILPDNE----------EIAVKRLSQSSRQGIEELK 498 L+ AT NF + LGEGGFG V+KG + + IAVK+L+Q QG +E Sbjct: 61 LKSATRNFRPDSVLGEGGFGCVFKGWIDEKSLTASRPGTGLVIAVKKLNQDGWQGHQEWL 120 Query: 499 NELVLVAKLQHKNLVRLLGVCLEEQEKLLAYEYMPNKSLDTILF 630 E+ + + H++LV+L+G CLE++ +LL YE+MP SL+ LF Sbjct: 121 AEVNYLGQFSHRHLVKLIGYCLEDEHRLLVYEFMPRGSLENHLF 164
>IRAK4_HUMAN (Q9NWZ3) Interleukin-1 receptor-associated kinase 4 (EC 2.7.11.1)| (IRAK-4) (NY-REN-64 antigen) Length = 460 Score = 79.3 bits (194), Expect = 9e-15 Identities = 48/99 (48%), Positives = 62/99 (62%), Gaps = 10/99 (10%) Frame = +1 Query: 349 LRVATDNFDER------NKLGEGGFGVVYKGILPDNEEIAVKRLSQSSRQGIEELKN--- 501 L+ T+NFDER NK+GEGGFGVVYKG + +N +AVK+L+ EELK Sbjct: 173 LKNVTNNFDERPISVGGNKMGEGGFGVVYKGYV-NNTTVAVKKLAAMVDITTEELKQQFD 231 Query: 502 -ELVLVAKLQHKNLVRLLGVCLEEQEKLLAYEYMPNKSL 615 E+ ++AK QH+NLV LLG + + L Y YMPN SL Sbjct: 232 QEIKVMAKCQHENLVELLGFSSDGDDLCLVYVYMPNGSL 270
>PBS1_ARATH (Q9FE20) Serine/threonine-protein kinase PBS1 (EC 2.7.11.1)| (AvrPphB susceptible protein 1) Length = 456 Score = 78.2 bits (191), Expect = 2e-14 Identities = 43/96 (44%), Positives = 59/96 (61%), Gaps = 1/96 (1%) Frame = +1 Query: 349 LRVATDNFDERNKLGEGGFGVVYKGILPDNEEI-AVKRLSQSSRQGIEELKNELVLVAKL 525 L AT NF LGEGGFG VYKG L ++ AVK+L ++ QG E E+++++ L Sbjct: 79 LAAATMNFHPDTFLGEGGFGRVYKGRLDSTGQVVAVKQLDRNGLQGNREFLVEVLMLSLL 138 Query: 526 QHKNLVRLLGVCLEEQEKLLAYEYMPNKSLDTILFD 633 H NLV L+G C + ++LL YE+MP SL+ L D Sbjct: 139 HHPNLVNLIGYCADGDQRLLVYEFMPLGSLEDHLHD 174
>BRL2_ARATH (Q9ZPS9) Serine/threonine-protein kinase BRI1-like 2 precursor (EC| 2.7.11.1) (BRASSINOSTEROID INSENSITIVE 1-like protein 2) (Protein VASCULAR HIGHWAY 1) Length = 1143 Score = 78.2 bits (191), Expect = 2e-14 Identities = 38/90 (42%), Positives = 56/90 (62%) Frame = +1 Query: 358 ATDNFDERNKLGEGGFGVVYKGILPDNEEIAVKRLSQSSRQGIEELKNELVLVAKLQHKN 537 AT+ F + +G GGFG V+K L D +A+K+L + S QG E E+ + K++H+N Sbjct: 834 ATNGFSAASMIGHGGFGEVFKATLKDGSSVAIKKLIRLSCQGDREFMAEMETLGKIKHRN 893 Query: 538 LVRLLGVCLEEQEKLLAYEYMPNKSLDTIL 627 LV LLG C +E+LL YE+M SL+ +L Sbjct: 894 LVPLLGYCKIGEERLLVYEFMQYGSLEEVL 923
>RLCK7_ARATH (Q9LQQ8) Probable serine/threonine-protein kinase RLCKVII (EC| 2.7.11.1) Length = 423 Score = 77.4 bits (189), Expect = 3e-14 Identities = 40/91 (43%), Positives = 58/91 (63%), Gaps = 1/91 (1%) Frame = +1 Query: 349 LRVATDNFDERNKLGEGGFGVVYKGILPDNEEI-AVKRLSQSSRQGIEELKNELVLVAKL 525 L AT NF LGEGGFG V+KG + +++ A+K+L ++ QGI E E++ ++ Sbjct: 96 LAEATGNFRSDCFLGEGGFGKVFKGTIEKLDQVVAIKQLDRNGVQGIREFVVEVLTLSLA 155 Query: 526 QHKNLVRLLGVCLEEQEKLLAYEYMPNKSLD 618 H NLV+L+G C E ++LL YEYMP SL+ Sbjct: 156 DHPNLVKLIGFCAEGDQRLLVYEYMPQGSLE 186
>IRAK4_MOUSE (Q8R4K2) Interleukin-1 receptor-associated kinase 4 (EC 2.7.11.1)| (IRAK-4) Length = 459 Score = 75.1 bits (183), Expect = 2e-13 Identities = 45/99 (45%), Positives = 59/99 (59%), Gaps = 10/99 (10%) Frame = +1 Query: 349 LRVATDNFDER------NKLGEGGFGVVYKGILPDNEEIAVKRLSQSSRQGIEELKN--- 501 L+ T+NFDE+ N++GEGGFGVVYKG + +N +AVK+L EELK Sbjct: 173 LKSITNNFDEQPASAGGNRMGEGGFGVVYKGCV-NNTIVAVKKLGAMVEISTEELKQQFD 231 Query: 502 -ELVLVAKLQHKNLVRLLGVCLEEQEKLLAYEYMPNKSL 615 E+ ++A QH+NLV LLG + L Y YMPN SL Sbjct: 232 QEIKVMATCQHENLVELLGFSSDSDNLCLVYAYMPNGSL 270
>CRI4_MAIZE (O24585) Putative receptor protein kinase CRINKLY4 precursor (EC| 2.7.11.1) Length = 901 Score = 74.3 bits (181), Expect = 3e-13 Identities = 39/91 (42%), Positives = 59/91 (64%), Gaps = 2/91 (2%) Frame = +1 Query: 349 LRVATDNFDERNKLGEGGFGVVYKGILPDNEEIAVKRLSQSS--RQGIEELKNELVLVAK 522 L AT F E +++G+G F V+KGIL D +AVKR ++S ++ +E NEL L+++ Sbjct: 498 LEQATGGFSEDSQVGKGSFSCVFKGILRDGTVVAVKRAIKASDVKKSSKEFHNELDLLSR 557 Query: 523 LQHKNLVRLLGVCLEEQEKLLAYEYMPNKSL 615 L H +L+ LLG C + E+LL YE+M + SL Sbjct: 558 LNHAHLLNLLGYCEDGSERLLVYEFMAHGSL 588
>KPRO_MAIZE (P17801) Putative receptor protein kinase ZmPK1 precursor (EC| 2.7.11.1) Length = 817 Score = 73.9 bits (180), Expect = 4e-13 Identities = 38/82 (46%), Positives = 53/82 (64%) Frame = +1 Query: 385 KLGEGGFGVVYKGILPDNEEIAVKRLSQSSRQGIEELKNELVLVAKLQHKNLVRLLGVCL 564 +LG G G VYKG+L D+ +AVK+L ++ RQG E + EL ++ ++ H NLVR+ G C Sbjct: 539 ELGRGESGTVYKGVLEDDRHVAVKKL-ENVRQGKEVFQAELSVIGRINHMNLVRIWGFCS 597 Query: 565 EEQEKLLAYEYMPNKSLDTILF 630 E +LL EY+ N SL ILF Sbjct: 598 EGSHRLLVSEYVENGSLANILF 619
>SIRK_ARATH (O64483) Senescence-induced receptor-like serine/threonine-protein| kinase precursor (FLG22-induced receptor-like kinase 1) Length = 876 Score = 73.2 bits (178), Expect = 6e-13 Identities = 38/89 (42%), Positives = 58/89 (65%) Frame = +1 Query: 361 TDNFDERNKLGEGGFGVVYKGILPDNEEIAVKRLSQSSRQGIEELKNELVLVAKLQHKNL 540 T+NF+ +G+GGFG VY G++ + E++AVK LS+ S QG +E + E+ L+ ++ H NL Sbjct: 573 TNNFER--VIGKGGFGKVYHGVI-NGEQVAVKVLSEESAQGYKEFRAEVDLLMRVHHTNL 629 Query: 541 VRLLGVCLEEQEKLLAYEYMPNKSLDTIL 627 L+G C E +L YEYM N++L L Sbjct: 630 TSLVGYCNEINHMVLIYEYMANENLGDYL 658
>CLV1_ARATH (Q9SYQ8) Receptor protein kinase CLAVATA1 precursor (EC 2.7.11.1)| Length = 980 Score = 70.5 bits (171), Expect = 4e-12 Identities = 33/85 (38%), Positives = 55/85 (64%), Gaps = 1/85 (1%) Frame = +1 Query: 376 ERNKLGEGGFGVVYKGILPDNEEIAVKRL-SQSSRQGIEELKNELVLVAKLQHKNLVRLL 552 E N +G+GG G+VY+G +P+N ++A+KRL + + + E+ + +++H+++VRLL Sbjct: 694 EENIIGKGGAGIVYRGSMPNNVDVAIKRLVGRGTGRSDHGFTAEIQTLGRIRHRHIVRLL 753 Query: 553 GVCLEEQEKLLAYEYMPNKSLDTIL 627 G + LL YEYMPN SL +L Sbjct: 754 GYVANKDTNLLLYEYMPNGSLGELL 778
>RLK5_ARATH (P47735) Receptor-like protein kinase 5 precursor (EC 2.7.11.1)| Length = 999 Score = 63.2 bits (152), Expect = 6e-10 Identities = 38/98 (38%), Positives = 54/98 (55%), Gaps = 10/98 (10%) Frame = +1 Query: 364 DNFDERNKLGEGGFGVVYKGILPDNEEIAVKRLSQSSRQGIEELKN----------ELVL 513 D DE+N +G G G VYK L E +AVK+L++S + G +E + E+ Sbjct: 681 DCLDEKNVIGFGSSGKVYKVELRGGEVVAVKKLNKSVKGGDDEYSSDSLNRDVFAAEVET 740 Query: 514 VAKLQHKNLVRLLGVCLEEQEKLLAYEYMPNKSLDTIL 627 + ++HK++VRL C KLL YEYMPN SL +L Sbjct: 741 LGTIRHKSIVRLWCCCSSGDCKLLVYEYMPNGSLADVL 778
>NTRK1_HUMAN (P04629) High affinity nerve growth factor receptor precursor (EC| 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 1) (TRK1 transforming tyrosine kinase protein) (p140-TrkA) (Trk-A) Length = 796 Score = 59.3 bits (142), Expect = 9e-09 Identities = 31/87 (35%), Positives = 52/87 (59%), Gaps = 6/87 (6%) Frame = +1 Query: 385 KLGEGGFGVVY----KGILPDNEE--IAVKRLSQSSRQGIEELKNELVLVAKLQHKNLVR 546 +LGEG FG V+ +LP+ ++ +AVK L ++S ++ + E L+ LQH+++VR Sbjct: 515 ELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKEASESARQDFQREAELLTMLQHQHIVR 574 Query: 547 LLGVCLEEQEKLLAYEYMPNKSLDTIL 627 GVC E + L+ +EYM + L+ L Sbjct: 575 FFGVCTEGRPLLMVFEYMRHGDLNRFL 601
>RPK1_IPONI (P93194) Receptor-like protein kinase precursor (EC 2.7.11.1)| Length = 1109 Score = 58.2 bits (139), Expect = 2e-08 Identities = 30/93 (32%), Positives = 54/93 (58%), Gaps = 1/93 (1%) Frame = +1 Query: 358 ATDNFDERNKLGEGGFGVVYKGILPDNEEIAVKRLSQSS-RQGIEELKNELVLVAKLQHK 534 AT+N +++ +G+G G +YK L ++ AVK+L + + G + E+ + K++H+ Sbjct: 812 ATENLNDKYVIGKGAHGTIYKATLSPDKVYAVKKLVFTGIKNGSVSMVREIETIGKVRHR 871 Query: 535 NLVRLLGVCLEEQEKLLAYEYMPNKSLDTILFD 633 NL++L L ++ L+ Y YM N SL IL + Sbjct: 872 NLIKLEEFWLRKEYGLILYTYMENGSLHDILHE 904
>SPK1_DUGTI (P42687) Tyrosine-protein kinase SPK-1 (EC 2.7.10.2)| Length = 497 Score = 57.0 bits (136), Expect = 5e-08 Identities = 35/95 (36%), Positives = 54/95 (56%), Gaps = 2/95 (2%) Frame = +1 Query: 349 LRVATDNFDERNKLGEGGFGVVYKGILPDNEEIAVKRLSQSSRQGIEELKNELVLVAKLQ 528 + + +N + N++G G FG V++ + E+A K L QSS+ E+ E ++ KL+ Sbjct: 213 IEINRENIEILNEIGRGFFGSVHRAKWGRSYEVAAKML-QSSKAEREKFVLEAKIMHKLR 271 Query: 529 HKNLVRLLGVCLEEQE--KLLAYEYMPNKSLDTIL 627 H+ +V LLGVC E Q+ L+ EYM N SL L Sbjct: 272 HRKIVELLGVCTEPQDMPMLIIVEYMKNGSLKEYL 306
>IRAK1_HUMAN (P51617) Interleukin-1 receptor-associated kinase 1 (EC 2.7.11.1)| (IRAK-1) Length = 712 Score = 57.0 bits (136), Expect = 5e-08 Identities = 32/90 (35%), Positives = 50/90 (55%), Gaps = 4/90 (4%) Frame = +1 Query: 361 TDNFDERNKLGEGGFGVVYKGILPDNEEIAVKRLSQSSRQGIEELK----NELVLVAKLQ 528 T NF E K+GEGGFG VY+ ++ N AVKRL +++ +K E+ +++ + Sbjct: 209 THNFSEELKIGEGGFGCVYRAVM-RNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFR 267 Query: 529 HKNLVRLLGVCLEEQEKLLAYEYMPNKSLD 618 H N+V G C + L Y ++PN SL+ Sbjct: 268 HPNIVDFAGYCAQNGFYCLVYGFLPNGSLE 297
>ROR1_DROME (Q24488) Tyrosine-protein kinase transmembrane receptor Ror| precursor (EC 2.7.10.1) (dRor) Length = 685 Score = 57.0 bits (136), Expect = 5e-08 Identities = 33/86 (38%), Positives = 54/86 (62%), Gaps = 5/86 (5%) Frame = +1 Query: 385 KLGEGGFGVVYKG-ILPDNEE---IAVKRLSQS-SRQGIEELKNELVLVAKLQHKNLVRL 549 +LGEG FG VYKG +L N+ +A+K L ++ S + ++ K E+ L++ L+H+N+V + Sbjct: 415 ELGEGAFGKVYKGQLLQPNKTTITVAIKALKENASVKTQQDFKREIELISDLKHQNIVCI 474 Query: 550 LGVCLEEQEKLLAYEYMPNKSLDTIL 627 LGV L ++ + +EYM N L L Sbjct: 475 LGVVLNKEPYCMLFEYMANGDLHEFL 500
>IRAK1_MOUSE (Q62406) Interleukin-1 receptor-associated kinase 1 (EC 2.7.11.1)| (IRAK-1) (IRAK) (Pelle-like protein kinase) (mPLK) Length = 710 Score = 55.8 bits (133), Expect = 1e-07 Identities = 32/90 (35%), Positives = 49/90 (54%), Gaps = 4/90 (4%) Frame = +1 Query: 361 TDNFDERNKLGEGGFGVVYKGILPDNEEIAVKRLSQSSRQGIEELK----NELVLVAKLQ 528 T NF E ++GEGGFG VY+ ++ N AVKRL + + +K E+ +++ + Sbjct: 209 TCNFSEELRIGEGGFGCVYRAVM-RNTTYAVKRLKEEADLEWTMVKQSFLTEVEQLSRFR 267 Query: 529 HKNLVRLLGVCLEEQEKLLAYEYMPNKSLD 618 H N+V G C E L Y ++PN SL+ Sbjct: 268 HPNIVDFAGYCAESGLYCLVYGFLPNGSLE 297
>NTRK1_RAT (P35739) High affinity nerve growth factor receptor precursor (EC| 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 1) (p140-TrkA) (Slow nerve growth factor receptor) (Trk-A) Length = 799 Score = 55.1 bits (131), Expect = 2e-07 Identities = 31/87 (35%), Positives = 49/87 (56%), Gaps = 6/87 (6%) Frame = +1 Query: 385 KLGEGGFGVVYKG----ILPDNEE--IAVKRLSQSSRQGIEELKNELVLVAKLQHKNLVR 546 +LGEG FG V+ +L D ++ +AVK L ++S ++ E L+ LQH+++VR Sbjct: 518 ELGEGAFGKVFLAECYNLLNDQDKMLVAVKALKETSENARQDFHREAELLTMLQHQHIVR 577 Query: 547 LLGVCLEEQEKLLAYEYMPNKSLDTIL 627 GVC E L+ +EYM + L+ L Sbjct: 578 FFGVCTEGGPLLMVFEYMRHGDLNRFL 604
>NTRK2_RAT (Q63604) BDNF/NT-3 growth factors receptor precursor (EC 2.7.10.1)| (Neurotrophic tyrosine kinase receptor type 2) (TrkB tyrosine kinase) (GP145-TrkB/GP95-TrkB) (Trk-B) Length = 821 Score = 54.3 bits (129), Expect = 3e-07 Identities = 29/89 (32%), Positives = 50/89 (56%), Gaps = 6/89 (6%) Frame = +1 Query: 379 RNKLGEGGFGVVYKG----ILPDNEEI--AVKRLSQSSRQGIEELKNELVLVAKLQHKNL 540 + +LGEG FG V+ + P+ ++I AVK L +S ++ E L+ LQH+++ Sbjct: 540 KRELGEGAFGKVFLAECYNLCPEQDKILVAVKTLKDASDNARKDFHREAELLTNLQHEHI 599 Query: 541 VRLLGVCLEEQEKLLAYEYMPNKSLDTIL 627 V+ GVC+E ++ +EYM + L+ L Sbjct: 600 VKFYGVCVEGDPLIMVFEYMKHGDLNKFL 628
>NTRK2_MOUSE (P15209) BDNF/NT-3 growth factors receptor precursor (EC 2.7.10.1)| (Neurotrophic tyrosine kinase receptor type 2) (TrkB tyrosine kinase) (GP145-TrkB/GP95-TrkB) (Trk-B) Length = 821 Score = 54.3 bits (129), Expect = 3e-07 Identities = 29/89 (32%), Positives = 50/89 (56%), Gaps = 6/89 (6%) Frame = +1 Query: 379 RNKLGEGGFGVVYKG----ILPDNEEI--AVKRLSQSSRQGIEELKNELVLVAKLQHKNL 540 + +LGEG FG V+ + P+ ++I AVK L +S ++ E L+ LQH+++ Sbjct: 540 KRELGEGAFGKVFLAECYNLCPEQDKILVAVKTLKDASDNARKDFHREAELLTNLQHEHI 599 Query: 541 VRLLGVCLEEQEKLLAYEYMPNKSLDTIL 627 V+ GVC+E ++ +EYM + L+ L Sbjct: 600 VKFYGVCVEGDPLIMVFEYMKHGDLNKFL 628
>NTRK2_HUMAN (Q16620) BDNF/NT-3 growth factors receptor precursor (EC 2.7.10.1)| (Neurotrophic tyrosine kinase receptor type 2) (TrkB tyrosine kinase) (GP145-TrkB) (Trk-B) Length = 822 Score = 54.3 bits (129), Expect = 3e-07 Identities = 29/89 (32%), Positives = 50/89 (56%), Gaps = 6/89 (6%) Frame = +1 Query: 379 RNKLGEGGFGVVYKG----ILPDNEEI--AVKRLSQSSRQGIEELKNELVLVAKLQHKNL 540 + +LGEG FG V+ + P+ ++I AVK L +S ++ E L+ LQH+++ Sbjct: 541 KRELGEGAFGKVFLAECYNLCPEQDKILVAVKTLKDASDNARKDFHREAELLTNLQHEHI 600 Query: 541 VRLLGVCLEEQEKLLAYEYMPNKSLDTIL 627 V+ GVC+E ++ +EYM + L+ L Sbjct: 601 VKFYGVCVEGDPLIMVFEYMKHGDLNKFL 629
>NTRK2_CHICK (Q91987) BDNF/NT-3 growth factors receptor precursor (EC 2.7.10.1)| (Neurotrophic tyrosine kinase receptor type 2) (TrkB tyrosine kinase) (Trk-B) Length = 818 Score = 54.3 bits (129), Expect = 3e-07 Identities = 29/89 (32%), Positives = 50/89 (56%), Gaps = 6/89 (6%) Frame = +1 Query: 379 RNKLGEGGFGVVYKG----ILPDNEEI--AVKRLSQSSRQGIEELKNELVLVAKLQHKNL 540 + +LGEG FG V+ + P+ ++I AVK L +S ++ E L+ LQH+++ Sbjct: 537 KRELGEGAFGKVFLAECYNLCPEQDKILVAVKTLKDASDNARKDFHREAELLTNLQHEHI 596 Query: 541 VRLLGVCLEEQEKLLAYEYMPNKSLDTIL 627 V+ GVC+E ++ +EYM + L+ L Sbjct: 597 VKFYGVCVEGDPLIMVFEYMKHGDLNKFL 625
>ROR2_DROME (Q9V6K3) Tyrosine-protein kinase transmembrane receptor Ror2| precursor (EC 2.7.10.1) (Neurospecific receptor tyrosine kinase) Length = 724 Score = 53.9 bits (128), Expect = 4e-07 Identities = 32/87 (36%), Positives = 49/87 (56%), Gaps = 7/87 (8%) Frame = +1 Query: 388 LGEGGFGVVYK----GILPDNEE--IAVKRLSQSSRQGIE-ELKNELVLVAKLQHKNLVR 546 LG+G FG V++ G++PD E+ +AVK L + ++ + + E L+A+ H N+VR Sbjct: 447 LGQGAFGRVFQARAPGLVPDQEDLLVAVKMLKDDASDQMQMDFEREACLLAEFDHPNIVR 506 Query: 547 LLGVCLEEQEKLLAYEYMPNKSLDTIL 627 LLGVC + L +EYM L L Sbjct: 507 LLGVCALGRPMCLLFEYMAPGDLSEFL 533
>ABL1_CAEEL (P03949) Tyrosine-protein kinase abl-1 (EC 2.7.10.2)| Length = 1224 Score = 53.5 bits (127), Expect = 5e-07 Identities = 33/79 (41%), Positives = 45/79 (56%), Gaps = 1/79 (1%) Frame = +1 Query: 382 NKLGEGGFGVVYKGILPDNE-EIAVKRLSQSSRQGIEELKNELVLVAKLQHKNLVRLLGV 558 NKLG G +G VY+G ++ IAVK L + + + E E ++ L HKNLVRLLGV Sbjct: 315 NKLGGGQYGDVYEGYWKRHDCTIAVKALKEDAMP-LHEFLAEAAIMKDLHHKNLVRLLGV 373 Query: 559 CLEEQEKLLAYEYMPNKSL 615 C E + E+M N +L Sbjct: 374 CTHEAPFYIITEFMCNGNL 392
>CDC2_CARAU (P51958) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1) Length = 302 Score = 53.5 bits (127), Expect = 5e-07 Identities = 33/93 (35%), Positives = 57/93 (61%), Gaps = 6/93 (6%) Frame = +1 Query: 364 DNFDERNKLGEGGFGVVYKGI-LPDNEEIAVKRLS-QSSRQGIEELK-NELVLVAKLQHK 534 D++ + K+GEG +GVVYKG + +A+K++ +S +G+ E+ L+ +LQH Sbjct: 2 DDYLKIEKIGEGTYGVVYKGRNKTTGQVVAMKKIRLESEEEGVPSTAVREISLLKELQHP 61 Query: 535 NLVRLLGVCLEEQEKLLAYEYMP---NKSLDTI 624 N+VRLL V ++E + L +E++ K LD+I Sbjct: 62 NVVRLLDVLMQESKLYLVFEFLSMDLKKYLDSI 94
>NTRK1_CHICK (Q91009) High affinity nerve growth factor receptor precursor (EC| 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 1) (Trk-A) (Fragment) Length = 778 Score = 53.1 bits (126), Expect = 7e-07 Identities = 29/87 (33%), Positives = 49/87 (56%), Gaps = 6/87 (6%) Frame = +1 Query: 385 KLGEGGFGVVYKG----ILPDNEE--IAVKRLSQSSRQGIEELKNELVLVAKLQHKNLVR 546 +LGEG FG V+ +LP+ E+ +AVK L + + + + E L+ LQH+++V+ Sbjct: 498 ELGEGAFGKVFLAECSHLLPEQEKTLVAVKALKEVTENARLDFQREAELLTVLQHEHIVK 557 Query: 547 LLGVCLEEQEKLLAYEYMPNKSLDTIL 627 GVC E ++ +EYM + L+ L Sbjct: 558 FYGVCTEGDPLIMVFEYMKHGDLNRFL 584
>ABL2_HUMAN (P42684) Tyrosine-protein kinase ABL2 (EC 2.7.10.2) (Abelson murine| leukemia viral oncogene homolog 2) (Tyrosine kinase ARG) Length = 1182 Score = 53.1 bits (126), Expect = 7e-07 Identities = 30/80 (37%), Positives = 47/80 (58%), Gaps = 1/80 (1%) Frame = +1 Query: 379 RNKLGEGGFGVVYKGILPDNE-EIAVKRLSQSSRQGIEELKNELVLVAKLQHKNLVRLLG 555 ++KLG G +G VY G+ +AVK L + + + +EE E ++ +++H NLV+LLG Sbjct: 291 KHKLGGGQYGEVYVGVWKKYSLTVAVKTLKEDTME-VEEFLKEAAVMKEIKHPNLVQLLG 349 Query: 556 VCLEEQEKLLAYEYMPNKSL 615 VC E + EYMP +L Sbjct: 350 VCTLEPPFYIVTEYMPYGNL 369
>ATG1_KLULA (Q6CSX2) Serine/threonine-protein kinase ATG1 (EC 2.7.11.1)| (Autophagy-related protein 1) Length = 831 Score = 52.8 bits (125), Expect = 9e-07 Identities = 28/87 (32%), Positives = 53/87 (60%), Gaps = 4/87 (4%) Frame = +1 Query: 349 LRVATDNFDERNKLGEGGFGVVYKGI-LPDNEEIAVKRLSQS---SRQGIEELKNELVLV 516 +R+ T+N+ ++G+G F VVYKG+ L D IA+K +S+S +++ +E L+ E+ ++ Sbjct: 14 IRLPTENYSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSKLKNKKLLENLEVEIAIL 73 Query: 517 AKLQHKNLVRLLGVCLEEQEKLLAYEY 597 K++H ++V L+ + L EY Sbjct: 74 KKIKHPHIVGLIDCERTSSDFYLIMEY 100
>M3KL4_HUMAN (Q5TCX8) Mitogen-activated protein kinase kinase kinase (EC| 2.7.11.25) (Mixed lineage kinase 4) Length = 1036 Score = 52.8 bits (125), Expect = 9e-07 Identities = 31/97 (31%), Positives = 49/97 (50%), Gaps = 4/97 (4%) Frame = +1 Query: 349 LRVATDNFDERNKLGEGGFGVVYKGILPDNEEIAVKRLSQSSRQ----GIEELKNELVLV 516 + VA + + + +G GGFG VY+ +E+AVK Q Q E ++ E L Sbjct: 117 VHVAFERLELKELIGAGGFGQVYRATW-QGQEVAVKAARQDPEQDAAAAAESVRREARLF 175 Query: 517 AKLQHKNLVRLLGVCLEEQEKLLAYEYMPNKSLDTIL 627 A L+H N++ L GVCL++ L E+ +L+ L Sbjct: 176 AMLRHPNIIELRGVCLQQPHLCLVLEFARGGALNRAL 212
>YSK4_HUMAN (Q56UN5) SPS1/STE20-related protein kinase YSK4 (EC 2.7.11.1)| (Regulated in COPD, protein kinase) Length = 1328 Score = 52.8 bits (125), Expect = 9e-07 Identities = 30/86 (34%), Positives = 50/86 (58%), Gaps = 6/86 (6%) Frame = +1 Query: 388 LGEGGFGVVYKGILPDNEEIAVKR--LSQSSRQGIEE----LKNELVLVAKLQHKNLVRL 549 LG+G +G VY G+ + IAVK+ L S++ E+ L+ E+ L+ L+H N+V Sbjct: 1067 LGKGAYGTVYCGLTSQGQLIAVKQVALDTSNKLAAEKEYRKLQEEVDLLKALKHVNIVAY 1126 Query: 550 LGVCLEEQEKLLAYEYMPNKSLDTIL 627 LG CL+E + E++P S+ +I+ Sbjct: 1127 LGTCLQENTVSIFMEFVPGGSISSII 1152
>FLK_RAT (P09760) Tyrosine-protein kinase FLK (EC 2.7.10.2) (Fragment)| Length = 323 Score = 52.4 bits (124), Expect = 1e-06 Identities = 26/73 (35%), Positives = 41/73 (56%), Gaps = 1/73 (1%) Frame = +1 Query: 388 LGEGGFGVVYKGILPDNEEIAVKRLSQSSRQGIE-ELKNELVLVAKLQHKNLVRLLGVCL 564 LG+G FG VYKG L D +AVK + Q ++ + E ++ + H N+V+L+GVC Sbjct: 70 LGKGNFGEVYKGTLKDKTPVAVKTCKEDLPQELKIKFLQEAKILKQYDHPNIVKLIGVCT 129 Query: 565 EEQEKLLAYEYMP 603 + Q + E +P Sbjct: 130 QRQPVYIIMELVP 142
>M3K2_ARATH (Q9FZ36) Mitogen-activated protein kinase kinase kinase 2 (EC| 2.7.11.25) (Arabidospsis NPK1-related protein kinase 2) Length = 651 Score = 52.0 bits (123), Expect = 1e-06 Identities = 29/89 (32%), Positives = 50/89 (56%), Gaps = 9/89 (10%) Frame = +1 Query: 388 LGEGGFGVVYKGI-LPDNEEIAVKRL--------SQSSRQGIEELKNELVLVAKLQHKNL 540 +G G FG VY G+ L E +AVK++ + ++ I+EL+ E+ L+ L H N+ Sbjct: 74 IGRGAFGTVYMGMNLDSGELLAVKQVLITSNCASKEKTQAHIQELEEEVKLLKNLSHPNI 133 Query: 541 VRLLGVCLEEQEKLLAYEYMPNKSLDTIL 627 VR LG E++ + E++P S+ ++L Sbjct: 134 VRYLGTVREDETLNILLEFVPGGSISSLL 162
>M3K4_HUMAN (Q9Y6R4) Mitogen-activated protein kinase kinase kinase 4 (EC| 2.7.11.25) (MAPK/ERK kinase kinase 4) (MEK kinase 4) (MEKK 4) (MAP three kinase 1) Length = 1607 Score = 52.0 bits (123), Expect = 1e-06 Identities = 33/95 (34%), Positives = 50/95 (52%), Gaps = 3/95 (3%) Frame = +1 Query: 349 LRVATDNFDERNKLGEGGFGVVYKGILPDNEEI-AVK--RLSQSSRQGIEELKNELVLVA 519 LR T + NK+GEG +G VY I D E+ A+K R + + I+E +EL + Sbjct: 1335 LRKVTFKWQRGNKIGEGQYGKVYTCISVDTGELMAMKEIRFQPNDHKTIKETADELKIFE 1394 Query: 520 KLQHKNLVRLLGVCLEEQEKLLAYEYMPNKSLDTI 624 ++H NLVR GV L +E + EY +L+ + Sbjct: 1395 GIKHPNLVRYFGVELHREEMYIFMEYCDEGTLEEV 1429
>M3K4_MOUSE (O08648) Mitogen-activated protein kinase kinase kinase 4 (EC| 2.7.11.25) (MAPK/ERK kinase kinase 4) (MEK kinase 4) (MEKK 4) Length = 1597 Score = 52.0 bits (123), Expect = 1e-06 Identities = 33/95 (34%), Positives = 50/95 (52%), Gaps = 3/95 (3%) Frame = +1 Query: 349 LRVATDNFDERNKLGEGGFGVVYKGILPDNEEI-AVK--RLSQSSRQGIEELKNELVLVA 519 LR T + NK+GEG +G VY I D E+ A+K R + + I+E +EL + Sbjct: 1325 LRKVTFKWQRGNKIGEGQYGKVYTCISVDTGELMAMKEIRFQPNDHKTIKETADELKIFE 1384 Query: 520 KLQHKNLVRLLGVCLEEQEKLLAYEYMPNKSLDTI 624 ++H NLVR GV L +E + EY +L+ + Sbjct: 1385 GIKHPNLVRYFGVELHREEMYIFMEYCDEGTLEEV 1419
>ITK_MOUSE (Q03526) Tyrosine-protein kinase ITK/TSK (EC 2.7.10.2)| (T-cell-specific kinase) (IL-2-inducible T-cell kinase) (Kinase EMT) (Kinase TLK) Length = 625 Score = 51.2 bits (121), Expect = 3e-06 Identities = 27/81 (33%), Positives = 45/81 (55%) Frame = +1 Query: 385 KLGEGGFGVVYKGILPDNEEIAVKRLSQSSRQGIEELKNELVLVAKLQHKNLVRLLGVCL 564 ++G G FG+V+ G + +++A+K + Q E+ E ++ KL H LV+L GVCL Sbjct: 373 EIGSGQFGLVHLGYWLNKDKVAIKTI-QEGAMSEEDFIEEAEVMMKLSHPKLVQLYGVCL 431 Query: 565 EEQEKLLAYEYMPNKSLDTIL 627 E+ L +E+M + L L Sbjct: 432 EQAPICLVFEFMEHGCLSDYL 452
>M3K1_ARATH (O22040) Mitogen-activated protein kinase kinase kinase 1 (EC| 2.7.11.25) (Arabidospsis NPK1-related protein kinase 1) Length = 666 Score = 51.2 bits (121), Expect = 3e-06 Identities = 29/89 (32%), Positives = 49/89 (55%), Gaps = 9/89 (10%) Frame = +1 Query: 388 LGEGGFGVVYKGI-LPDNEEIAVKRL--------SQSSRQGIEELKNELVLVAKLQHKNL 540 +G G FG VY G+ L E +AVK++ + ++ I+EL+ E+ L+ L H N+ Sbjct: 75 IGRGAFGTVYMGMNLDSGELLAVKQVLIAANFASKEKTQAHIQELEEEVKLLKNLSHPNI 134 Query: 541 VRLLGVCLEEQEKLLAYEYMPNKSLDTIL 627 VR LG E+ + E++P S+ ++L Sbjct: 135 VRYLGTVREDDTLNILLEFVPGGSISSLL 163
>FER_HUMAN (P16591) Proto-oncogene tyrosine-protein kinase FER (EC 2.7.10.2)| (p94-FER) (c-FER) Length = 822 Score = 50.8 bits (120), Expect = 3e-06 Identities = 27/81 (33%), Positives = 42/81 (51%), Gaps = 1/81 (1%) Frame = +1 Query: 388 LGEGGFGVVYKGILPDNEEIAVKRLSQSSRQGIE-ELKNELVLVAKLQHKNLVRLLGVCL 564 LG+G FG VYKG L D +AVK + Q ++ + E ++ + H N+V+L+GVC Sbjct: 569 LGKGNFGEVYKGTLKDKTSVAVKTCKEDLPQELKIKFLQEAKILKQYDHPNIVKLIGVCT 628 Query: 565 EEQEKLLAYEYMPNKSLDTIL 627 + Q + E + T L Sbjct: 629 QRQPVYIIMELVSGGDFLTFL 649
>CRK1_LEIME (Q06309) Cell division protein kinase 2 homolog CRK1 (EC 2.7.11.23)| Length = 301 Score = 50.8 bits (120), Expect = 3e-06 Identities = 28/83 (33%), Positives = 48/83 (57%), Gaps = 3/83 (3%) Frame = +1 Query: 361 TDNFDERNKLGEGGFGVVYKGILPDNEE-IAVKRLS-QSSRQGIE-ELKNELVLVAKLQH 531 T ++ + K+GEG +GVVYK +A+KR+ S +G+ E+ L+ +L+H Sbjct: 2 TSRYERQEKIGEGTYGVVYKARDTSTAATVALKRIRLDSEEEGVPCTAIREISLLKELRH 61 Query: 532 KNLVRLLGVCLEEQEKLLAYEYM 600 +N+V+LL VC E + +EY+ Sbjct: 62 ENIVKLLDVCHSEHRLTIVFEYL 84
>ERBB4_HUMAN (Q15303) Receptor tyrosine-protein kinase erbB-4 precursor (EC| 2.7.10.1) (p180erbB4) (Tyrosine kinase-type cell surface receptor HER4) Length = 1308 Score = 50.8 bits (120), Expect = 3e-06 Identities = 36/96 (37%), Positives = 57/96 (59%), Gaps = 7/96 (7%) Frame = +1 Query: 349 LRVATDNFDERNK-LGEGGFGVVYKGI-LPDNEEI----AVKRLSQSSRQGIE-ELKNEL 507 LR+ + +R K LG G FG VYKGI +P+ E + A+K L++++ E +E Sbjct: 710 LRILKETELKRVKVLGSGAFGTVYKGIWVPEGETVKIPVAIKILNETTGPKANVEFMDEA 769 Query: 508 VLVAKLQHKNLVRLLGVCLEEQEKLLAYEYMPNKSL 615 +++A + H +LVRLLGVCL +L+ + MP+ L Sbjct: 770 LIMASMDHPHLVRLLGVCLSPTIQLVT-QLMPHGCL 804
>BUR1_KLULA (Q6CRA9) Serine/threonine-protein kinase BUR1 (EC 2.7.11.22) (EC| 2.7.11.23) Length = 645 Score = 50.8 bits (120), Expect = 3e-06 Identities = 24/72 (33%), Positives = 47/72 (65%), Gaps = 3/72 (4%) Frame = +1 Query: 364 DNFDERNKLGEGGFGVVYKGI-LPDNEEIAVKRLSQSSRQGIEEL--KNELVLVAKLQHK 534 +N+ E KLG+G FG V+KGI L N ++A+KR+ + + + + + E+ ++ ++ HK Sbjct: 53 NNYREEEKLGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPITAQREITILKRMNHK 112 Query: 535 NLVRLLGVCLEE 570 N+V+L+ + +E Sbjct: 113 NIVKLIEIVYDE 124
>ABL1_MOUSE (P00520) Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2)| (p150) (c-ABL) (Abelson murine leukemia viral oncogene homolog 1) Length = 1123 Score = 50.4 bits (119), Expect = 4e-06 Identities = 27/75 (36%), Positives = 45/75 (60%), Gaps = 1/75 (1%) Frame = +1 Query: 379 RNKLGEGGFGVVYKGILPDNE-EIAVKRLSQSSRQGIEELKNELVLVAKLQHKNLVRLLG 555 ++KLG G +G VY+G+ +AVK L + + + +EE E ++ +++H NLV+LLG Sbjct: 245 KHKLGGGQYGEVYEGVWKKYSLTVAVKTLKEDTME-VEEFLKEAAVMKEIKHPNLVQLLG 303 Query: 556 VCLEEQEKLLAYEYM 600 VC E + E+M Sbjct: 304 VCTREPPFYIITEFM 318
>CDC22_ORYSA (P29619) Cell division control protein 2 homolog 2 (EC 2.7.11.22)| Length = 292 Score = 50.4 bits (119), Expect = 4e-06 Identities = 31/82 (37%), Positives = 48/82 (58%), Gaps = 3/82 (3%) Frame = +1 Query: 364 DNFDERNKLGEGGFGVVYKGI-LPDNEEIAVK--RLSQSSRQGIEELKNELVLVAKLQHK 534 + +++ K+GEG +GVVYKG NE IA+K RL Q E+ L+ ++QH+ Sbjct: 2 EQYEKVEKIGEGTYGVVYKGKHRHTNETIALKKIRLEQEDEGVPSTAIREISLLKEMQHR 61 Query: 535 NLVRLLGVCLEEQEKLLAYEYM 600 N+VRL V +E+ L +EY+ Sbjct: 62 NIVRLQDVVHKEKCIYLVFEYL 83
>ITK_HUMAN (Q08881) Tyrosine-protein kinase ITK/TSK (EC 2.7.10.2)| (T-cell-specific kinase) (Tyrosine-protein kinase Lyk) (Kinase EMT) Length = 620 Score = 50.4 bits (119), Expect = 4e-06 Identities = 26/81 (32%), Positives = 46/81 (56%) Frame = +1 Query: 385 KLGEGGFGVVYKGILPDNEEIAVKRLSQSSRQGIEELKNELVLVAKLQHKNLVRLLGVCL 564 ++G G FG+V+ G + +++A+K + + + E+ E ++ KL H LV+L GVCL Sbjct: 368 EIGSGQFGLVHLGYWLNKDKVAIKTIREGAMSE-EDFIEEAEVMMKLSHPKLVQLYGVCL 426 Query: 565 EEQEKLLAYEYMPNKSLDTIL 627 E+ L +E+M + L L Sbjct: 427 EQAPICLVFEFMEHGCLSDYL 447
>ABL_MLVAB (P00521) Tyrosine-protein kinase transforming protein Abl (EC| 2.7.10.2) (V-abl) Length = 746 Score = 50.4 bits (119), Expect = 4e-06 Identities = 27/75 (36%), Positives = 45/75 (60%), Gaps = 1/75 (1%) Frame = +1 Query: 379 RNKLGEGGFGVVYKGILPDNE-EIAVKRLSQSSRQGIEELKNELVLVAKLQHKNLVRLLG 555 ++KLG G +G VY+G+ +AVK L + + + +EE E ++ +++H NLV+LLG Sbjct: 131 KHKLGGGQYGEVYEGVWKKYSLTVAVKTLKEDTME-VEEFLKEAAVMKEIKHPNLVQLLG 189 Query: 556 VCLEEQEKLLAYEYM 600 VC E + E+M Sbjct: 190 VCTREPPFYIITEFM 204
>ABL_FSVHY (P10447) Tyrosine-protein kinase transforming protein Abl (EC| 2.7.10.2) (V-abl) Length = 439 Score = 50.4 bits (119), Expect = 4e-06 Identities = 27/75 (36%), Positives = 45/75 (60%), Gaps = 1/75 (1%) Frame = +1 Query: 379 RNKLGEGGFGVVYKGILPDNE-EIAVKRLSQSSRQGIEELKNELVLVAKLQHKNLVRLLG 555 ++KLG G +G VY+G+ +AVK L + + + +EE E ++ +++H NLV+LLG Sbjct: 194 KHKLGGGQYGEVYEGVWKKYSLTVAVKTLKEDTME-VEEFLKEAAVMKEIKHPNLVQLLG 252 Query: 556 VCLEEQEKLLAYEYM 600 VC E + E+M Sbjct: 253 VCTREPPFYIITEFM 267
>ABL1_HUMAN (P00519) Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2)| (p150) (c-ABL) (Abelson murine leukemia viral oncogene homolog 1) Length = 1130 Score = 50.4 bits (119), Expect = 4e-06 Identities = 27/75 (36%), Positives = 45/75 (60%), Gaps = 1/75 (1%) Frame = +1 Query: 379 RNKLGEGGFGVVYKGILPDNE-EIAVKRLSQSSRQGIEELKNELVLVAKLQHKNLVRLLG 555 ++KLG G +G VY+G+ +AVK L + + + +EE E ++ +++H NLV+LLG Sbjct: 245 KHKLGGGQYGEVYEGVWKKYSLTVAVKTLKEDTME-VEEFLKEAAVMKEIKHPNLVQLLG 303 Query: 556 VCLEEQEKLLAYEYM 600 VC E + E+M Sbjct: 304 VCTREPPFYIITEFM 318
>ERBB4_RAT (Q62956) Receptor tyrosine-protein kinase erbB-4 precursor (EC| 2.7.10.1) Length = 1308 Score = 50.4 bits (119), Expect = 4e-06 Identities = 36/96 (37%), Positives = 57/96 (59%), Gaps = 7/96 (7%) Frame = +1 Query: 349 LRVATDNFDERNK-LGEGGFGVVYKGI-LPDNEEI----AVKRLSQSSRQGIE-ELKNEL 507 LR+ + +R K LG G FG VYKGI +P+ E + A+K L++++ E +E Sbjct: 710 LRILKETELKRVKVLGSGAFGTVYKGIWVPEGETVKIPVAIKILNETTGPKANVEFMDEA 769 Query: 508 VLVAKLQHKNLVRLLGVCLEEQEKLLAYEYMPNKSL 615 +++A + H +LVRLLGVCL +L+ + MP+ L Sbjct: 770 LIMASVDHPHLVRLLGVCLSPTIQLVT-QLMPHGCL 804
>ROR2_MOUSE (Q9Z138) Tyrosine-protein kinase transmembrane receptor ROR2| precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase, receptor-related 2) (mROR2) Length = 944 Score = 50.4 bits (119), Expect = 4e-06 Identities = 40/131 (30%), Positives = 62/131 (47%), Gaps = 8/131 (6%) Frame = +1 Query: 259 STPARKTSLSYPTIP-EXXXXXXXXXXXXXTLRVATDNFDERNKLGEGGFGVVYKGIL-- 429 STP R+ ++ P+ E + ++T F E +LGE FG VYKG L Sbjct: 437 STPQRRQLMASPSQDMEMPLISQHKQAKLKEISLSTVRFME--ELGEDRFGKVYKGHLFG 494 Query: 430 ----PDNEEIAVKRLSQSSRQGI-EELKNELVLVAKLQHKNLVRLLGVCLEEQEKLLAYE 594 + +A+K L + + EE + E +L A+LQH N+V LLGV ++Q + + Sbjct: 495 PAPGEPTQAVAIKTLKDKAEGPLREEFRQEAMLRARLQHPNIVCLLGVVTKDQPLSMIFS 554 Query: 595 YMPNKSLDTIL 627 Y + L L Sbjct: 555 YCSHGDLHEFL 565
>CDC22_MEDSA (Q05006) Cell division control protein 2 homolog 2 (EC 2.7.11.22)| Length = 294 Score = 50.1 bits (118), Expect = 6e-06 Identities = 30/82 (36%), Positives = 46/82 (56%), Gaps = 3/82 (3%) Frame = +1 Query: 364 DNFDERNKLGEGGFGVVYKGI-LPDNEEIAVK--RLSQSSRQGIEELKNELVLVAKLQHK 534 + +++ K+GEG +GVVYK NE IA+K RL Q E+ L+ ++QH+ Sbjct: 2 EQYEKVEKIGEGTYGVVYKARDRATNETIALKKIRLEQEDEGVPSTAIREISLLKEMQHR 61 Query: 535 NLVRLLGVCLEEQEKLLAYEYM 600 N+VRL V E+ L +EY+ Sbjct: 62 NIVRLQDVVHSEKRLYLVFEYL 83
>NTRK3_CHICK (Q91044) NT-3 growth factor receptor precursor (EC 2.7.10.1)| (Neurotrophic tyrosine kinase receptor type 3) (TrkC tyrosine kinase) (Trk-C) Length = 827 Score = 50.1 bits (118), Expect = 6e-06 Identities = 27/89 (30%), Positives = 49/89 (55%), Gaps = 6/89 (6%) Frame = +1 Query: 379 RNKLGEGGFGVVYKG----ILPDNEE--IAVKRLSQSSRQGIEELKNELVLVAKLQHKNL 540 + +LGEG FG V+ + P N++ +AVK L + ++ + E L+ LQH+++ Sbjct: 543 KRELGEGAFGKVFLAECYNLSPTNDKMLVAVKALKDPTLAARKDFQREAELLTNLQHEHI 602 Query: 541 VRLLGVCLEEQEKLLAYEYMPNKSLDTIL 627 V+ GVC + ++ +EYM + L+ L Sbjct: 603 VKFYGVCGDGDPLIMVFEYMKHGDLNKFL 631
>CDC2_RANDY (Q9W739) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) Length = 302 Score = 50.1 bits (118), Expect = 6e-06 Identities = 30/93 (32%), Positives = 55/93 (59%), Gaps = 6/93 (6%) Frame = +1 Query: 364 DNFDERNKLGEGGFGVVYKGI-LPDNEEIAVKRLS-QSSRQGIEELK-NELVLVAKLQHK 534 D + + K+GEG +GVVYKG+ + +A+K++ ++ +G+ E+ L+ +LQH Sbjct: 2 DEYAKIEKIGEGTYGVVYKGVHKATGQIVAMKKIRLENEEEGVPSTAIREISLLKELQHP 61 Query: 535 NLVRLLGVCLEEQEKLLAYEYMP---NKSLDTI 624 N+V LL V +++ L +E++ K LD+I Sbjct: 62 NIVCLLDVLMQDSRLYLIFEFLSMDLKKYLDSI 94
>CDC2_ORYLU (Q9DG98) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1) Length = 303 Score = 49.7 bits (117), Expect = 7e-06 Identities = 31/93 (33%), Positives = 56/93 (60%), Gaps = 6/93 (6%) Frame = +1 Query: 364 DNFDERNKLGEGGFGVVYKGILPDNEEI-AVKRLS-QSSRQGIEELK-NELVLVAKLQHK 534 +++ + K+GEG +GVVYKG ++ A+K++ +S +G+ E+ L+ +L+H Sbjct: 2 EDYVKIEKIGEGTYGVVYKGRHKSTGQVVAMKKIRLESEEEGVPSTAVREVSLLQELKHP 61 Query: 535 NLVRLLGVCLEEQEKLLAYEYMP---NKSLDTI 624 N+VRLL V ++E L +E++ K LD+I Sbjct: 62 NVVRLLDVLMQESRLYLIFEFLSMDLKKYLDSI 94
>CDC2_ORYLA (Q9DGD3) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1) Length = 303 Score = 49.7 bits (117), Expect = 7e-06 Identities = 31/93 (33%), Positives = 56/93 (60%), Gaps = 6/93 (6%) Frame = +1 Query: 364 DNFDERNKLGEGGFGVVYKGILPDNEEI-AVKRLS-QSSRQGIEELK-NELVLVAKLQHK 534 +++ + K+GEG +GVVYKG ++ A+K++ +S +G+ E+ L+ +L+H Sbjct: 2 EDYVKIEKIGEGTYGVVYKGRHKSTGQVVAMKKIRLESEEEGVPSTAVREVSLLQELKHP 61 Query: 535 NLVRLLGVCLEEQEKLLAYEYMP---NKSLDTI 624 N+VRLL V ++E L +E++ K LD+I Sbjct: 62 NVVRLLDVLMQESRLYLIFEFLSMDLKKYLDSI 94
>CDC2_ORYJA (Q9DGA2) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1) Length = 303 Score = 49.7 bits (117), Expect = 7e-06 Identities = 31/93 (33%), Positives = 56/93 (60%), Gaps = 6/93 (6%) Frame = +1 Query: 364 DNFDERNKLGEGGFGVVYKGILPDNEEI-AVKRLS-QSSRQGIEELK-NELVLVAKLQHK 534 +++ + K+GEG +GVVYKG ++ A+K++ +S +G+ E+ L+ +L+H Sbjct: 2 EDYVKIEKIGEGTYGVVYKGRHKSTGQVVAMKKIRLESEEEGVPSTAVREVSLLQELKHP 61 Query: 535 NLVRLLGVCLEEQEKLLAYEYMP---NKSLDTI 624 N+VRLL V ++E L +E++ K LD+I Sbjct: 62 NVVRLLDVLMQESRLYLIFEFLSMDLKKYLDSI 94
>CDC2_ORYCU (Q9DGA5) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1) Length = 303 Score = 49.7 bits (117), Expect = 7e-06 Identities = 31/93 (33%), Positives = 56/93 (60%), Gaps = 6/93 (6%) Frame = +1 Query: 364 DNFDERNKLGEGGFGVVYKGILPDNEEI-AVKRLS-QSSRQGIEELK-NELVLVAKLQHK 534 +++ + K+GEG +GVVYKG ++ A+K++ +S +G+ E+ L+ +L+H Sbjct: 2 EDYVKIEKIGEGTYGVVYKGRHKSTGQVVAMKKIRLESEEEGVPSTAVREVSLLQELKHP 61 Query: 535 NLVRLLGVCLEEQEKLLAYEYMP---NKSLDTI 624 N+VRLL V ++E L +E++ K LD+I Sbjct: 62 NVVRLLDVLMQESRLYLIFEFLSMDLKKYLDSI 94
>CDC2_VIGAC (Q41639) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34cdc2) Length = 294 Score = 49.7 bits (117), Expect = 7e-06 Identities = 30/82 (36%), Positives = 46/82 (56%), Gaps = 3/82 (3%) Frame = +1 Query: 364 DNFDERNKLGEGGFGVVYKGI-LPDNEEIAVK--RLSQSSRQGIEELKNELVLVAKLQHK 534 + +++ K+GEG +GVVYK NE IA+K RL Q E+ L+ ++QH+ Sbjct: 2 EQYEKVEKIGEGTYGVVYKARDRVTNETIALKKIRLEQEDEGVPSTAIREISLLKEMQHR 61 Query: 535 NLVRLLGVCLEEQEKLLAYEYM 600 N+VRL V E+ L +EY+ Sbjct: 62 NIVRLQDVVHSEKRLYLVFEYL 83
>CDC2_CHERU (P93101) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34cdc2) Length = 294 Score = 49.7 bits (117), Expect = 7e-06 Identities = 31/82 (37%), Positives = 45/82 (54%), Gaps = 3/82 (3%) Frame = +1 Query: 364 DNFDERNKLGEGGFGVVYKGI-LPDNEEIAVK--RLSQSSRQGIEELKNELVLVAKLQHK 534 D +++ K+GEG +GVVYK NE IA+K RL Q E+ L+ ++QH Sbjct: 2 DQYEKVEKIGEGTYGVVYKARDKVTNETIALKKIRLEQEDEGVPSTAIREISLLKEMQHG 61 Query: 535 NLVRLLGVCLEEQEKLLAYEYM 600 N+VRL V E+ L +EY+ Sbjct: 62 NIVRLQDVVHSEKRLYLVFEYL 83
>ZYG1_CAEBR (Q621J7) Probable serine/threonine-protein kinase zyg-1 (EC| 2.7.11.1) (Zygote defective protein 1) Length = 709 Score = 49.3 bits (116), Expect = 1e-05 Identities = 25/83 (30%), Positives = 44/83 (53%) Frame = +1 Query: 367 NFDERNKLGEGGFGVVYKGILPDNEEIAVKRLSQSSRQGIEELKNELVLVAKLQHKNLVR 546 +F ++G+GGFGVVY + E++A+K++ ++ Q +K E+ + L+H+N+V+ Sbjct: 12 SFQNLQQIGQGGFGVVYSAQRENGEKVAIKKIGNAASQ--TRIKEEIKTMKLLRHRNIVQ 69 Query: 547 LLGVCLEEQEKLLAYEYMPNKSL 615 E E L E SL Sbjct: 70 FYETFFENGETYLVMELCEGGSL 92
>CDC2A_ARATH (P24100) Cell division control protein 2 homolog A (EC 2.7.11.22)| (EC 2.7.11.23) Length = 294 Score = 49.3 bits (116), Expect = 1e-05 Identities = 30/82 (36%), Positives = 45/82 (54%), Gaps = 3/82 (3%) Frame = +1 Query: 364 DNFDERNKLGEGGFGVVYKGI-LPDNEEIAVK--RLSQSSRQGIEELKNELVLVAKLQHK 534 D +++ K+GEG +GVVYK NE IA+K RL Q E+ L+ ++QH Sbjct: 2 DQYEKVEKIGEGTYGVVYKARDKVTNETIALKKIRLEQEDEGVPSTAIREISLLKEMQHS 61 Query: 535 NLVRLLGVCLEEQEKLLAYEYM 600 N+V+L V E+ L +EY+ Sbjct: 62 NIVKLQDVVHSEKRLYLVFEYL 83
>M3K9_HUMAN (P80192) Mitogen-activated protein kinase kinase kinase 9 (EC| 2.7.11.25) (Mixed lineage kinase 1) Length = 1104 Score = 49.3 bits (116), Expect = 1e-05 Identities = 30/84 (35%), Positives = 44/84 (52%), Gaps = 4/84 (4%) Frame = +1 Query: 388 LGEGGFGVVYKGILPDNEEIAVKRL----SQSSRQGIEELKNELVLVAKLQHKNLVRLLG 555 +G GGFG VY+ +E+AVK + Q IE ++ E L A L+H N++ L G Sbjct: 150 IGIGGFGKVYRAFWI-GDEVAVKAARHDPDEDISQTIENVRQEAKLFAMLKHPNIIALRG 208 Query: 556 VCLEEQEKLLAYEYMPNKSLDTIL 627 VCL+E L E+ L+ +L Sbjct: 209 VCLKEPNLCLVMEFARGGPLNRVL 232
>CC2H1_TRYCO (P54664) Cell division control protein 2 homolog 1 (EC 2.7.11.22)| Length = 301 Score = 49.3 bits (116), Expect = 1e-05 Identities = 28/80 (35%), Positives = 48/80 (60%), Gaps = 3/80 (3%) Frame = +1 Query: 370 FDERNKLGEGGFGVVYKGI-LPDNEEIAVKRLS-QSSRQGIE-ELKNELVLVAKLQHKNL 540 + K+GEG +GVVY+ + + +A+KR+ +S +G+ E+ ++ +L+H+N+ Sbjct: 5 YQRLEKIGEGSYGVVYRARDITTDVIVALKRIRLESVEEGVPCTAIREISILKELRHENI 64 Query: 541 VRLLGVCLEEQEKLLAYEYM 600 VRLL VC E L +EYM Sbjct: 65 VRLLDVCHSENRLNLVFEYM 84
>ROR2_HUMAN (Q01974) Tyrosine-protein kinase transmembrane receptor ROR2| precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase, receptor-related 2) Length = 943 Score = 49.3 bits (116), Expect = 1e-05 Identities = 31/88 (35%), Positives = 47/88 (53%), Gaps = 7/88 (7%) Frame = +1 Query: 385 KLGEGGFGVVYKGIL------PDNEEIAVKRLSQSSRQGI-EELKNELVLVAKLQHKNLV 543 +LGE FG VYKG L + +A+K L + + EE ++E +L A+LQH N+V Sbjct: 478 ELGEDRFGKVYKGHLFGPAPGEQTQAVAIKTLKDKAEGPLREEFRHEAMLRARLQHPNVV 537 Query: 544 RLLGVCLEEQEKLLAYEYMPNKSLDTIL 627 LLGV ++Q + + Y + L L Sbjct: 538 CLLGVVTKDQPLSMIFSYCSHGDLHEFL 565
>MUSK_CHICK (Q8AXY6) Muscle, skeletal receptor tyrosine protein kinase| precursor (EC 2.7.10.1) (Muscle-specific tyrosine protein kinase receptor) (Muscle-specific kinase receptor) (MuSK) Length = 947 Score = 48.9 bits (115), Expect = 1e-05 Identities = 32/103 (31%), Positives = 54/103 (52%), Gaps = 7/103 (6%) Frame = +1 Query: 346 TLRVATDNFDERNKLGEGGFGVVYK----GILPDNE--EIAVKRLSQSSRQGIE-ELKNE 504 +L +N + +GEG FG V++ G+LP +AVK L + + ++ + + E Sbjct: 647 SLEYPRNNIEYVRDIGEGAFGRVFQARAPGLLPYEPFTMVAVKMLKEEASADMQADFQRE 706 Query: 505 LVLVAKLQHKNLVRLLGVCLEEQEKLLAYEYMPNKSLDTILFD 633 L+A+ + N+V+LLGVC + L +EYM L+ L D Sbjct: 707 AALMAEFDNPNIVKLLGVCAVGKPMCLLFEYMAYGDLNEYLRD 749
>AURKC_HUMAN (Q9UQB9) Serine/threonine-protein kinase 13 (EC 2.7.11.1)| (Aurora/Ipl1/Eg2 protein 2) (Aurora/Ipl1-related kinase 3) (Aurora-C) Length = 309 Score = 48.9 bits (115), Expect = 1e-05 Identities = 30/92 (32%), Positives = 49/92 (53%), Gaps = 4/92 (4%) Frame = +1 Query: 352 RVATDNFDERNKLGEGGFGVVYKGILPDNEEIAVKRL---SQSSRQGIE-ELKNELVLVA 519 R+ D+F+ LG+G FG VY L ++ I ++ SQ ++G+E +L+ E+ + A Sbjct: 37 RLTVDDFEIGRPLGKGKFGNVYLARLKESHFIVALKVLFKSQIEKEGLEHQLRREIEIQA 96 Query: 520 KLQHKNLVRLLGVCLEEQEKLLAYEYMPNKSL 615 LQH N++RL + + L EY P L Sbjct: 97 HLQHPNILRLYNYFHDARRVYLILEYAPRGEL 128
>BTKL_DROME (P08630) Tyrosine-protein kinase Btk29A (EC 2.7.10.2) (Dsrc28C)| Length = 786 Score = 48.9 bits (115), Expect = 1e-05 Identities = 28/77 (36%), Positives = 44/77 (57%) Frame = +1 Query: 385 KLGEGGFGVVYKGILPDNEEIAVKRLSQSSRQGIEELKNELVLVAKLQHKNLVRLLGVCL 564 +LG G FGVV +G + + AVK + + + ++ E ++ KLQH NLV+L GVC Sbjct: 531 ELGSGQFGVVRRGKWRGSIDTAVKMMKEGTMSE-DDFIEEAKVMTKLQHPNLVQLYGVCS 589 Query: 565 EEQEKLLAYEYMPNKSL 615 + + + EYM + SL Sbjct: 590 KHRPIYIVTEYMKHGSL 606
>TXK_HUMAN (P42681) Tyrosine-protein kinase TXK (EC 2.7.10.2)| Length = 527 Score = 48.9 bits (115), Expect = 1e-05 Identities = 25/77 (32%), Positives = 44/77 (57%) Frame = +1 Query: 385 KLGEGGFGVVYKGILPDNEEIAVKRLSQSSRQGIEELKNELVLVAKLQHKNLVRLLGVCL 564 ++G G FGVV+ G + ++A+K +++ S E+ E ++ KL H LV+L GVC+ Sbjct: 276 EIGSGQFGVVHLGEWRSHIQVAIKAINEGSMSE-EDFIEEAKVMMKLSHSKLVQLYGVCI 334 Query: 565 EEQEKLLAYEYMPNKSL 615 + + + E+M N L Sbjct: 335 QRKPLYIVTEFMENGCL 351
>LCK_SAISC (Q95KR7) Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2)| (p56-LCK) (Lymphocyte cell-specific protein-tyrosine kinase) Length = 508 Score = 48.9 bits (115), Expect = 1e-05 Identities = 32/77 (41%), Positives = 43/77 (55%) Frame = +1 Query: 385 KLGEGGFGVVYKGILPDNEEIAVKRLSQSSRQGIEELKNELVLVAKLQHKNLVRLLGVCL 564 +LG G FG V+ G ++ ++AVK L Q S + E L+ +LQHK LVRL V Sbjct: 249 RLGAGQFGEVWMGYYNEHTKVAVKSLKQGS-MSPDAFLAEANLMKQLQHKRLVRLYAVVT 307 Query: 565 EEQEKLLAYEYMPNKSL 615 EE ++ EYM N SL Sbjct: 308 EEPIYIIT-EYMENGSL 323
>CDK5_DROME (P48609) Cell division protein kinase 5 homolog (EC 2.7.11.22)| Length = 294 Score = 48.5 bits (114), Expect = 2e-05 Identities = 28/79 (35%), Positives = 48/79 (60%), Gaps = 3/79 (3%) Frame = +1 Query: 370 FDERNKLGEGGFGVVYKGILPDNEEI-AVKRLS-QSSRQGI-EELKNELVLVAKLQHKNL 540 +D+ K+GEG +G V+KG D EI A+KR+ +G+ E+ L+ +L+HKN+ Sbjct: 4 YDKMEKIGEGTYGTVFKGRNRDTMEIVALKRVRLDEDDEGVPSSALREICLLKELKHKNI 63 Query: 541 VRLLGVCLEEQEKLLAYEY 597 VRL+ V +++ L +E+ Sbjct: 64 VRLIDVLHSDKKLTLVFEH 82
>STK_HYDAT (P17713) Tyrosine-protein kinase STK (EC 2.7.10.2) (P57-STK)| Length = 509 Score = 48.5 bits (114), Expect = 2e-05 Identities = 27/77 (35%), Positives = 43/77 (55%) Frame = +1 Query: 385 KLGEGGFGVVYKGILPDNEEIAVKRLSQSSRQGIEELKNELVLVAKLQHKNLVRLLGVCL 564 KLG G FG V+ G+ + ++AVK L + L +E ++ KL+HK+LV+L +C Sbjct: 245 KLGAGQFGEVWAGVWNNTTQVAVKTLKPGTMSPASFL-DEAGVMKKLRHKHLVQLYAICS 303 Query: 565 EEQEKLLAYEYMPNKSL 615 + + + EYM SL Sbjct: 304 DREPIYIVTEYMSGGSL 320
>MERTK_HUMAN (Q12866) Proto-oncogene tyrosine-protein kinase MER precursor (EC| 2.7.10.1) (C-mer) (Receptor tyrosine kinase MerTK) Length = 999 Score = 48.5 bits (114), Expect = 2e-05 Identities = 28/66 (42%), Positives = 39/66 (59%), Gaps = 6/66 (9%) Frame = +1 Query: 388 LGEGGFGVVYKGILPDNE----EIAVK--RLSQSSRQGIEELKNELVLVAKLQHKNLVRL 549 LGEG FG V +G L + ++AVK +L SS + IEE +E + H N++RL Sbjct: 593 LGEGEFGSVMEGNLKQEDGTSLKVAVKTMKLDNSSHREIEEFLSEAACMKDFSHPNVIRL 652 Query: 550 LGVCLE 567 LGVC+E Sbjct: 653 LGVCIE 658
>JAK2_MOUSE (Q62120) Tyrosine-protein kinase JAK2 (EC 2.7.10.2) (Janus kinase 2)| (JAK-2) Length = 1129 Score = 48.5 bits (114), Expect = 2e-05 Identities = 33/94 (35%), Positives = 51/94 (54%), Gaps = 12/94 (12%) Frame = +1 Query: 370 FDERN-----KLGEGGFGVVYK---GILPDN--EEIAVKRLSQSSRQGIEELKNELVLVA 519 F+ER+ +LG+G FG V L DN E +AVK+L S+ + + + + E+ ++ Sbjct: 844 FEERHLKFLQQLGKGNFGSVEMCRYDPLQDNTGEVVAVKKLQHSTEEHLRDFEREIEILK 903 Query: 520 KLQHKNLVRLLGVCLE--EQEKLLAYEYMPNKSL 615 LQH N+V+ GVC + L EY+P SL Sbjct: 904 SLQHDNIVKYKGVCYSAGRRNLRLIMEYLPYGSL 937 Score = 45.4 bits (106), Expect = 1e-04 Identities = 27/100 (27%), Positives = 50/100 (50%), Gaps = 8/100 (8%) Frame = +1 Query: 352 RVATDNFDERNKLGEGGFGVVYKGILPD--------NEEIAVKRLSQSSRQGIEELKNEL 507 ++ ++ LG+G F ++KG+ + E+ +K L ++ R E Sbjct: 539 KIRNEDLIFNESLGQGTFTKIFKGVRREVGDYGQLHKTEVLLKVLDKAHRNYSESFFEAA 598 Query: 508 VLVAKLQHKNLVRLLGVCLEEQEKLLAYEYMPNKSLDTIL 627 ++++L HK+LV GVC+ +E +L E++ SLDT L Sbjct: 599 SMMSQLSHKHLVLNYGVCVCGEENILVQEFVKFGSLDTYL 638
>TRK1_LYMST (O76997) Putative neurotrophin receptor LTRK 1 precursor (EC| 2.7.10.1) Length = 794 Score = 48.5 bits (114), Expect = 2e-05 Identities = 28/87 (32%), Positives = 48/87 (55%), Gaps = 7/87 (8%) Frame = +1 Query: 388 LGEGGFGVVYKG----ILPDNEE--IAVKRLSQSSRQGIE-ELKNELVLVAKLQHKNLVR 546 +GEG FG V+ G ++ NE +AVK L S ++ + + E ++A ++H N+V Sbjct: 510 IGEGAFGRVFLGTCAHLIQKNEFAIVAVKTLKGSCSDSLKRDFEREAEMLATIEHANIVT 569 Query: 547 LLGVCLEEQEKLLAYEYMPNKSLDTIL 627 GVC E + ++ +E+M N L+ L Sbjct: 570 FYGVCTESDQWMMIFEFMENGDLNKYL 596
>EGFR_DROME (P04412) Epidermal growth factor receptor precursor (EC 2.7.10.1)| (Egfr) (Gurken receptor) (Protein torpedo) (Drosophila relative of ERBB) Length = 1426 Score = 48.5 bits (114), Expect = 2e-05 Identities = 30/78 (38%), Positives = 46/78 (58%), Gaps = 6/78 (7%) Frame = +1 Query: 388 LGEGGFGVVYKGI-LPDNEEI----AVKRLSQSS-RQGIEELKNELVLVAKLQHKNLVRL 549 LG G FG VYKG+ +P+ E + A+K L +S+ + EE E ++A +H NL++L Sbjct: 944 LGMGAFGRVYKGVWVPEGENVKIPVAIKELLKSTGAESSEEFLREAYIMASEEHVNLLKL 1003 Query: 550 LGVCLEEQEKLLAYEYMP 603 L VC+ Q L+ + MP Sbjct: 1004 LAVCMSSQMMLIT-QLMP 1020
>JAK2_RAT (Q62689) Tyrosine-protein kinase JAK2 (EC 2.7.10.2) (Janus kinase 2)| (JAK-2) Length = 1132 Score = 48.5 bits (114), Expect = 2e-05 Identities = 33/94 (35%), Positives = 51/94 (54%), Gaps = 12/94 (12%) Frame = +1 Query: 370 FDERN-----KLGEGGFGVVYK---GILPDN--EEIAVKRLSQSSRQGIEELKNELVLVA 519 F+ER+ +LG+G FG V L DN E +AVK+L S+ + + + + E+ ++ Sbjct: 844 FEERHLKFLQQLGKGNFGSVEMCRYDPLQDNTGEVVAVKKLQHSTEEHLRDFEREIEILK 903 Query: 520 KLQHKNLVRLLGVCLE--EQEKLLAYEYMPNKSL 615 LQH N+V+ GVC + L EY+P SL Sbjct: 904 SLQHDNIVKYKGVCYSAGRRNLRLIMEYLPYGSL 937 Score = 45.4 bits (106), Expect = 1e-04 Identities = 27/100 (27%), Positives = 50/100 (50%), Gaps = 8/100 (8%) Frame = +1 Query: 352 RVATDNFDERNKLGEGGFGVVYKGILPD--------NEEIAVKRLSQSSRQGIEELKNEL 507 ++ ++ LG+G F ++KG+ + E+ +K L ++ R E Sbjct: 539 KIRNEDLIFNESLGQGTFTKIFKGVRREVGDYGQLHETEVLLKVLDKAHRNYSESFFEAA 598 Query: 508 VLVAKLQHKNLVRLLGVCLEEQEKLLAYEYMPNKSLDTIL 627 ++++L HK+LV GVC+ +E +L E++ SLDT L Sbjct: 599 SMMSQLSHKHLVLNYGVCVCGEENILVQEFVKFGSLDTYL 638
>JAK2_HUMAN (O60674) Tyrosine-protein kinase JAK2 (EC 2.7.10.2) (Janus kinase 2)| (JAK-2) Length = 1132 Score = 48.5 bits (114), Expect = 2e-05 Identities = 33/94 (35%), Positives = 51/94 (54%), Gaps = 12/94 (12%) Frame = +1 Query: 370 FDERN-----KLGEGGFGVVYK---GILPDN--EEIAVKRLSQSSRQGIEELKNELVLVA 519 F+ER+ +LG+G FG V L DN E +AVK+L S+ + + + + E+ ++ Sbjct: 844 FEERHLKFLQQLGKGNFGSVEMCRYDPLQDNTGEVVAVKKLQHSTEEHLRDFEREIEILK 903 Query: 520 KLQHKNLVRLLGVCLE--EQEKLLAYEYMPNKSL 615 LQH N+V+ GVC + L EY+P SL Sbjct: 904 SLQHDNIVKYKGVCYSAGRRNLKLIMEYLPYGSL 937 Score = 46.2 bits (108), Expect = 8e-05 Identities = 28/100 (28%), Positives = 49/100 (49%), Gaps = 8/100 (8%) Frame = +1 Query: 352 RVATDNFDERNKLGEGGFGVVYKGILPD--------NEEIAVKRLSQSSRQGIEELKNEL 507 ++ ++ LG+G F ++KG+ + E+ +K L ++ R E Sbjct: 539 KIRNEDLIFNESLGQGTFTKIFKGVRREVGDYGQLHETEVLLKVLDKAHRNYSESFFEAA 598 Query: 508 VLVAKLQHKNLVRLLGVCLEEQEKLLAYEYMPNKSLDTIL 627 +++KL HK+LV GVC+ E +L E++ SLDT L Sbjct: 599 SMMSKLSHKHLVLNYGVCVCGDENILVQEFVKFGSLDTYL 638
>PHO85_CANGA (Q6FKD4) Negative regulator of the PHO system (EC 2.7.11.22)| (Serine/threonine-protein kinase PHO85) Length = 302 Score = 48.5 bits (114), Expect = 2e-05 Identities = 28/86 (32%), Positives = 45/86 (52%), Gaps = 2/86 (2%) Frame = +1 Query: 355 VATDNFDERNKLGEGGFGVVYKGILPDNEE-IAVKRLSQSSRQGIEELK-NELVLVAKLQ 528 +++ F + KLG G + VYKG+ +A+K + S +G E+ L+ +L+ Sbjct: 1 MSSSQFKQLEKLGNGTYATVYKGLNKSTGVYVALKEVKLDSEEGTPSTAIREISLMKELK 60 Query: 529 HKNLVRLLGVCLEEQEKLLAYEYMPN 606 H N+VRL V E + L +EYM N Sbjct: 61 HDNIVRLYDVIHTENKLTLVFEYMDN 86
>CDC22_XENLA (P24033) Cell division control protein 2 homolog 2 (EC 2.7.11.22)| (EC 2.7.11.23) (p34 protein kinase 2) Length = 302 Score = 48.5 bits (114), Expect = 2e-05 Identities = 30/93 (32%), Positives = 54/93 (58%), Gaps = 6/93 (6%) Frame = +1 Query: 364 DNFDERNKLGEGGFGVVYKGI-LPDNEEIAVKRLS-QSSRQGIEELK-NELVLVAKLQHK 534 D + + K+GEG +GVVYKG + +A+K++ ++ +G+ E+ L+ +LQH Sbjct: 2 DEYTKIEKIGEGTYGVVYKGRHKATGQVVAMKKIRLENEEEGVPSTAIREISLLKELQHP 61 Query: 535 NLVRLLGVCLEEQEKLLAYEYMP---NKSLDTI 624 N+V LL V +++ L +E++ K LD+I Sbjct: 62 NIVCLLDVLMQDSRLYLIFEFLSMDVKKYLDSI 94
>CDC21_XENLA (P35567) Cell division control protein 2 homolog 1 (EC 2.7.11.22)| (EC 2.7.11.23) (p34 protein kinase 1) Length = 302 Score = 48.5 bits (114), Expect = 2e-05 Identities = 30/93 (32%), Positives = 54/93 (58%), Gaps = 6/93 (6%) Frame = +1 Query: 364 DNFDERNKLGEGGFGVVYKGI-LPDNEEIAVKRLS-QSSRQGIEELK-NELVLVAKLQHK 534 D + + K+GEG +GVVYKG + +A+K++ ++ +G+ E+ L+ +LQH Sbjct: 2 DEYTKIEKIGEGTYGVVYKGRHKATGQVVAMKKIRLENEEEGVPSTAIREISLLKELQHP 61 Query: 535 NLVRLLGVCLEEQEKLLAYEYMP---NKSLDTI 624 N+V LL V +++ L +E++ K LD+I Sbjct: 62 NIVCLLDVLMQDSRLYLIFEFLSMDLKKYLDSI 94
>M3KSL_DROME (Q95UN8) Mitogen-activated protein kinase kinase kinase (EC| 2.7.11.25) (Mixed lineage kinase) (dMLK) (Protein slipper) Length = 1161 Score = 48.1 bits (113), Expect = 2e-05 Identities = 30/92 (32%), Positives = 50/92 (54%), Gaps = 4/92 (4%) Frame = +1 Query: 364 DNFDERNKLGEGGFGVVYKGILPDNEEIAVKRLSQSSRQGIEELKNELVLVAK----LQH 531 + D + +G GGF V++G D EE+A+K Q+ ++ +++ ++ AK L+H Sbjct: 140 NELDIKEVIGSGGFCKVHRGYY-DGEEVAIKIAHQTGEDDMQRMRDNVLQEAKLFWALKH 198 Query: 532 KNLVRLLGVCLEEQEKLLAYEYMPNKSLDTIL 627 +N+ L GVCL + L EY SL+ IL Sbjct: 199 ENIAALRGVCL-NTKLCLVMEYARGGSLNRIL 229
>MUSK_HUMAN (O15146) Muscle, skeletal receptor tyrosine protein kinase| precursor (EC 2.7.10.1) (Muscle-specific tyrosine protein kinase receptor) (Muscle-specific kinase receptor) (MuSK) Length = 869 Score = 48.1 bits (113), Expect = 2e-05 Identities = 31/101 (30%), Positives = 53/101 (52%), Gaps = 7/101 (6%) Frame = +1 Query: 346 TLRVATDNFDERNKLGEGGFGVVYK----GILPDNE--EIAVKRLSQSSRQGIE-ELKNE 504 +L +N + +GEG FG V++ G+LP +AVK L + + ++ + + E Sbjct: 567 SLEYPRNNIEYVRDIGEGAFGRVFQARAPGLLPYEPFTMVAVKMLKEEASADMQADFQRE 626 Query: 505 LVLVAKLQHKNLVRLLGVCLEEQEKLLAYEYMPNKSLDTIL 627 L+A+ + N+V+LLGVC + L +EYM L+ L Sbjct: 627 AALMAEFDNPNIVKLLGVCAVGKPMCLLFEYMAYGDLNEFL 667
>KPEL_DROME (Q05652) Probable serine/threonine-protein kinase pelle (EC| 2.7.11.1) Length = 501 Score = 48.1 bits (113), Expect = 2e-05 Identities = 33/99 (33%), Positives = 54/99 (54%), Gaps = 6/99 (6%) Frame = +1 Query: 349 LRVATDNFDERNKLGEGGFGVVYKGILPDNEEIAVKRLSQSS---RQGIEELK---NELV 510 L ATD + N+LG+GGFG VY+G ++A+K ++ S Q + EL+ NEL Sbjct: 206 LENATDGWSPDNRLGQGGFGDVYRGKW-KQLDVAIKVMNYRSPNIDQKMVELQQSYNELK 264 Query: 511 LVAKLQHKNLVRLLGVCLEEQEKLLAYEYMPNKSLDTIL 627 + ++H N++ L G ++ + L Y+ M SL+ L Sbjct: 265 YLNSIRHDNILALYGYSIKGGKPCLVYQLMKGGSLEARL 303
>CDC2A_ANTMA (Q38772) Cell division control protein 2 homolog A (EC 2.7.11.22)| (EC 2.7.11.23) Length = 294 Score = 48.1 bits (113), Expect = 2e-05 Identities = 30/82 (36%), Positives = 45/82 (54%), Gaps = 3/82 (3%) Frame = +1 Query: 364 DNFDERNKLGEGGFGVVYKGI-LPDNEEIAVK--RLSQSSRQGIEELKNELVLVAKLQHK 534 + +++ K+GEG +GVVYK NE IA+K RL Q E+ L+ ++QH Sbjct: 2 EQYEKVEKIGEGTYGVVYKARDRVTNETIALKKIRLEQEDEGVPSTAIREISLLKEMQHG 61 Query: 535 NLVRLLGVCLEEQEKLLAYEYM 600 N+VRL V E+ L +EY+ Sbjct: 62 NIVRLQDVVHSEKRLYLVFEYL 83
>M3K3_ARATH (O22042) Mitogen-activated protein kinase kinase kinase 3 (EC| 2.7.11.25) (Arabidospsis NPK1-related protein kinase 3) Length = 651 Score = 48.1 bits (113), Expect = 2e-05 Identities = 31/89 (34%), Positives = 48/89 (53%), Gaps = 9/89 (10%) Frame = +1 Query: 388 LGEGGFGVVYKGI-LPDNEEIAVKRL-------SQSSRQG-IEELKNELVLVAKLQHKNL 540 +G G FG VY G+ L E +A+K++ S+ QG I EL+ E+ L+ L H N+ Sbjct: 74 IGCGAFGRVYMGMNLDSGELLAIKQVLIAPSSASKEKTQGHIRELEEEVQLLKNLSHPNI 133 Query: 541 VRLLGVCLEEQEKLLAYEYMPNKSLDTIL 627 VR LG E + E++P S+ ++L Sbjct: 134 VRYLGTVRESDSLNILMEFVPGGSISSLL 162
>XMRK_XIPMA (P13388) Melanoma receptor tyrosine-protein kinase precursor (EC| 2.7.10.1) Length = 1167 Score = 48.1 bits (113), Expect = 2e-05 Identities = 30/84 (35%), Positives = 49/84 (58%), Gaps = 6/84 (7%) Frame = +1 Query: 370 FDERNKLGEGGFGVVYKGIL-PDNEEI----AVKRLSQSSRQGI-EELKNELVLVAKLQH 531 F + LG G FG VYKG+ PD E I A+K L +++ + +E+ +E ++A + H Sbjct: 710 FKKDRVLGSGAFGTVYKGLWNPDGENIRIPVAIKVLREATSPKVNQEVLDEAYVMASVDH 769 Query: 532 KNLVRLLGVCLEEQEKLLAYEYMP 603 ++ RLLG+CL +L+ + MP Sbjct: 770 PHVCRLLGICLTSAVQLVT-QLMP 792
>MUSK_RAT (Q62838) Muscle, skeletal receptor tyrosine protein kinase| precursor (EC 2.7.10.1) (Muscle-specific kinase receptor) (MuSK) Length = 868 Score = 48.1 bits (113), Expect = 2e-05 Identities = 31/101 (30%), Positives = 53/101 (52%), Gaps = 7/101 (6%) Frame = +1 Query: 346 TLRVATDNFDERNKLGEGGFGVVYK----GILPDNE--EIAVKRLSQSSRQGIE-ELKNE 504 +L +N + +GEG FG V++ G+LP +AVK L + + ++ + + E Sbjct: 566 SLEYPRNNIEYVRDIGEGAFGRVFQARAPGLLPYEPFTMVAVKMLKEEASADMQADFQRE 625 Query: 505 LVLVAKLQHKNLVRLLGVCLEEQEKLLAYEYMPNKSLDTIL 627 L+A+ + N+V+LLGVC + L +EYM L+ L Sbjct: 626 AALMAEFDNPNIVKLLGVCAVGKPMCLLFEYMAYGDLNEFL 666
>MUSK_MOUSE (Q61006) Muscle, skeletal receptor tyrosine protein kinase| precursor (EC 2.7.10.1) (Muscle-specific kinase receptor) (MuSK) Length = 868 Score = 48.1 bits (113), Expect = 2e-05 Identities = 31/101 (30%), Positives = 53/101 (52%), Gaps = 7/101 (6%) Frame = +1 Query: 346 TLRVATDNFDERNKLGEGGFGVVYK----GILPDNE--EIAVKRLSQSSRQGIE-ELKNE 504 +L +N + +GEG FG V++ G+LP +AVK L + + ++ + + E Sbjct: 566 SLEYPRNNIEYVRDIGEGAFGRVFQARAPGLLPYEPFTMVAVKMLKEEASADMQADFQRE 625 Query: 505 LVLVAKLQHKNLVRLLGVCLEEQEKLLAYEYMPNKSLDTIL 627 L+A+ + N+V+LLGVC + L +EYM L+ L Sbjct: 626 AALMAEFDNPNIVKLLGVCAVGKPMCLLFEYMAYGDLNEFL 666
>LCK_AOTNA (Q5PXS1) Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2)| (p56-LCK) (Lymphocyte cell-specific protein-tyrosine kinase) Length = 508 Score = 47.8 bits (112), Expect = 3e-05 Identities = 31/77 (40%), Positives = 43/77 (55%) Frame = +1 Query: 385 KLGEGGFGVVYKGILPDNEEIAVKRLSQSSRQGIEELKNELVLVAKLQHKNLVRLLGVCL 564 +LG G FG V+ G D+ ++AVK L Q S + E L+ +LQH+ LVRL V Sbjct: 249 RLGAGQFGEVWMGYYNDHTKVAVKSLKQGS-MSPDAFLAEANLMKQLQHQRLVRLYAVVT 307 Query: 565 EEQEKLLAYEYMPNKSL 615 +E ++ EYM N SL Sbjct: 308 QEPIYIIT-EYMENGSL 323
>ERBB3_RAT (Q62799) Receptor tyrosine-protein kinase erbB-3 precursor (EC| 2.7.10.1) (c-erbB3) Length = 1339 Score = 47.8 bits (112), Expect = 3e-05 Identities = 29/82 (35%), Positives = 46/82 (56%), Gaps = 6/82 (7%) Frame = +1 Query: 388 LGEGGFGVVYKGI-LPDNEEIAVKRL-----SQSSRQGIEELKNELVLVAKLQHKNLVRL 549 LG G FG V+KGI +P+ E I + +S RQ + + + ++ V L H ++VRL Sbjct: 713 LGSGVFGTVHKGIWIPEGESIKIPVCIKVIEDKSGRQSFQAVTDHMLAVGSLDHAHIVRL 772 Query: 550 LGVCLEEQEKLLAYEYMPNKSL 615 LG+C +L+ +Y+P SL Sbjct: 773 LGLCPGSSLQLVT-QYLPLGSL 793
>ERBB3_MOUSE (Q61526) Receptor tyrosine-protein kinase erbB-3 precursor (EC| 2.7.10.1) (c-erbB3) (Glial growth factor receptor) Length = 1339 Score = 47.8 bits (112), Expect = 3e-05 Identities = 29/82 (35%), Positives = 46/82 (56%), Gaps = 6/82 (7%) Frame = +1 Query: 388 LGEGGFGVVYKGI-LPDNEEIAVKRL-----SQSSRQGIEELKNELVLVAKLQHKNLVRL 549 LG G FG V+KGI +P+ E I + +S RQ + + + ++ V L H ++VRL Sbjct: 713 LGSGVFGTVHKGIWIPEGESIKIPVCIKVIEDKSGRQSFQAVTDHMLAVGSLDHAHIVRL 772 Query: 550 LGVCLEEQEKLLAYEYMPNKSL 615 LG+C +L+ +Y+P SL Sbjct: 773 LGLCPGSSLQLVT-QYLPLGSL 793
>NTRK3_HUMAN (Q16288) NT-3 growth factor receptor precursor (EC 2.7.10.1)| (Neurotrophic tyrosine kinase receptor type 3) (TrkC tyrosine kinase) (GP145-TrkC) (Trk-C) Length = 839 Score = 47.8 bits (112), Expect = 3e-05 Identities = 26/89 (29%), Positives = 48/89 (53%), Gaps = 6/89 (6%) Frame = +1 Query: 379 RNKLGEGGFGVVYKG----ILPDNEE--IAVKRLSQSSRQGIEELKNELVLVAKLQHKNL 540 + +LGEG FG V+ + P ++ +AVK L + ++ + E L+ LQH+++ Sbjct: 541 KRELGEGAFGKVFLAECYNLSPTKDKMLVAVKALKDPTLAARKDFQREAELLTNLQHEHI 600 Query: 541 VRLLGVCLEEQEKLLAYEYMPNKSLDTIL 627 V+ GVC + ++ +EYM + L+ L Sbjct: 601 VKFYGVCGDGDPLIMVFEYMKHGDLNKFL 629
>NTRK3_SAIBB (Q5IS82) NT-3 growth factor receptor precursor (EC 2.7.10.1)| (Neurotrophic tyrosine kinase receptor type 3) Length = 825 Score = 47.8 bits (112), Expect = 3e-05 Identities = 26/89 (29%), Positives = 48/89 (53%), Gaps = 6/89 (6%) Frame = +1 Query: 379 RNKLGEGGFGVVYKG----ILPDNEE--IAVKRLSQSSRQGIEELKNELVLVAKLQHKNL 540 + +LGEG FG V+ + P ++ +AVK L + ++ + E L+ LQH+++ Sbjct: 541 KRELGEGAFGKVFLAECYNLSPTKDKMLVAVKALKDPTLAARKDFQREAELLTNLQHEHI 600 Query: 541 VRLLGVCLEEQEKLLAYEYMPNKSLDTIL 627 V+ GVC + ++ +EYM + L+ L Sbjct: 601 VKFYGVCGDGDPLIMVFEYMKHGDLNKFL 629
>NTRK3_PANTR (Q5IS37) NT-3 growth factor receptor precursor (EC 2.7.10.1)| (Neurotrophic tyrosine kinase receptor type 3) Length = 825 Score = 47.8 bits (112), Expect = 3e-05 Identities = 26/89 (29%), Positives = 48/89 (53%), Gaps = 6/89 (6%) Frame = +1 Query: 379 RNKLGEGGFGVVYKG----ILPDNEE--IAVKRLSQSSRQGIEELKNELVLVAKLQHKNL 540 + +LGEG FG V+ + P ++ +AVK L + ++ + E L+ LQH+++ Sbjct: 541 KRELGEGAFGKVFLAECYNLSPTKDKMLVAVKALKDPTLAARKDFQREAELLTNLQHEHI 600 Query: 541 VRLLGVCLEEQEKLLAYEYMPNKSLDTIL 627 V+ GVC + ++ +EYM + L+ L Sbjct: 601 VKFYGVCGDGDPLIMVFEYMKHGDLNKFL 629
>NTRK3_MACFA (Q5IFJ9) NT-3 growth factor receptor precursor (EC 2.7.10.1)| (Neurotrophic tyrosine kinase receptor type 3) Length = 825 Score = 47.8 bits (112), Expect = 3e-05 Identities = 26/89 (29%), Positives = 48/89 (53%), Gaps = 6/89 (6%) Frame = +1 Query: 379 RNKLGEGGFGVVYKG----ILPDNEE--IAVKRLSQSSRQGIEELKNELVLVAKLQHKNL 540 + +LGEG FG V+ + P ++ +AVK L + ++ + E L+ LQH+++ Sbjct: 541 KRELGEGAFGKVFLAECYNLSPTKDKMLVAVKALKDPTLAARKDFQREAELLTNLQHEHI 600 Query: 541 VRLLGVCLEEQEKLLAYEYMPNKSLDTIL 627 V+ GVC + ++ +EYM + L+ L Sbjct: 601 VKFYGVCGDGDPLIMVFEYMKHGDLNKFL 629
>CDC2_VIGUN (P52389) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34cdc2) Length = 294 Score = 47.8 bits (112), Expect = 3e-05 Identities = 29/82 (35%), Positives = 46/82 (56%), Gaps = 3/82 (3%) Frame = +1 Query: 364 DNFDERNKLGEGGFGVVYKGI-LPDNEEIAVK--RLSQSSRQGIEELKNELVLVAKLQHK 534 + +++ K+GEG +GVVYK +E IA+K RL Q E+ L+ ++QH+ Sbjct: 2 EQYEKVEKIGEGTYGVVYKARDRVTDETIALKKIRLEQEDEGVPSTAIREISLLKEMQHR 61 Query: 535 NLVRLLGVCLEEQEKLLAYEYM 600 N+VRL V E+ L +EY+ Sbjct: 62 NIVRLQDVVHSEKRLYLVFEYL 83
>CDC2_MAIZE (P23111) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34cdc2) Length = 294 Score = 47.8 bits (112), Expect = 3e-05 Identities = 29/82 (35%), Positives = 45/82 (54%), Gaps = 3/82 (3%) Frame = +1 Query: 364 DNFDERNKLGEGGFGVVYKGI-LPDNEEIAVK--RLSQSSRQGIEELKNELVLVAKLQHK 534 + +++ K+GEG +GVVYK + NE IA+K RL Q E+ L+ ++ H Sbjct: 2 EQYEKVEKIGEGTYGVVYKALDKATNETIALKKIRLEQEDEGVPSTAIREISLLKEMNHG 61 Query: 535 NLVRLLGVCLEEQEKLLAYEYM 600 N+VRL V E+ L +EY+ Sbjct: 62 NIVRLHDVVHSEKRIYLVFEYL 83
>NTRK3_RAT (Q03351) NT-3 growth factor receptor precursor (EC 2.7.10.1)| (Neurotrophic tyrosine kinase receptor type 3) (TrkC tyrosine kinase) (GP145-TrkC) (Trk-C) Length = 864 Score = 47.8 bits (112), Expect = 3e-05 Identities = 26/89 (29%), Positives = 48/89 (53%), Gaps = 6/89 (6%) Frame = +1 Query: 379 RNKLGEGGFGVVYKG----ILPDNEE--IAVKRLSQSSRQGIEELKNELVLVAKLQHKNL 540 + +LGEG FG V+ + P ++ +AVK L + ++ + E L+ LQH+++ Sbjct: 541 KRELGEGAFGKVFLAECYNLSPTKDKMLVAVKALKDPTLAARKDFQREAELLTNLQHEHI 600 Query: 541 VRLLGVCLEEQEKLLAYEYMPNKSLDTIL 627 V+ GVC + ++ +EYM + L+ L Sbjct: 601 VKFYGVCGDGDPLIMVFEYMKHGDLNKFL 629
>BUR1_CANGA (Q6FQ83) Serine/threonine-protein kinase BUR1 (EC 2.7.11.22) (EC| 2.7.11.23) Length = 667 Score = 47.8 bits (112), Expect = 3e-05 Identities = 23/65 (35%), Positives = 41/65 (63%), Gaps = 3/65 (4%) Frame = +1 Query: 367 NFDERNKLGEGGFGVVYKGI-LPDNEEIAVKRLSQSSRQGIEEL--KNELVLVAKLQHKN 537 N+ E KLG+G FG VYKG+ L ++A+KR+ + + + + E+ ++ +L HKN Sbjct: 59 NYKEEEKLGQGTFGEVYKGLHLQTQRKVAMKRIIVNQENDLFPITAQREITILKRLNHKN 118 Query: 538 LVRLL 552 +++LL Sbjct: 119 IIKLL 123
>TXK_MOUSE (P42682) Tyrosine-protein kinase TXK (EC 2.7.10.2) (PTK-RL-18)| (Resting lymphocyte kinase) Length = 527 Score = 47.8 bits (112), Expect = 3e-05 Identities = 25/77 (32%), Positives = 44/77 (57%) Frame = +1 Query: 385 KLGEGGFGVVYKGILPDNEEIAVKRLSQSSRQGIEELKNELVLVAKLQHKNLVRLLGVCL 564 ++G G FGVV+ G + +A+K +++ S E+ E ++ KL H LV+L GVC+ Sbjct: 276 EIGSGQFGVVHLGEWRAHIPVAIKAINEGSMSE-EDFIEEAKVMMKLSHSRLVQLYGVCI 334 Query: 565 EEQEKLLAYEYMPNKSL 615 +++ + E+M N L Sbjct: 335 QQKPLYIVTEFMENGCL 351
>PHO85_KLULA (Q92241) Negative regulator of the PHO system (EC 2.7.11.22)| (Serine/threonine-protein kinase PHO85) Length = 304 Score = 47.8 bits (112), Expect = 3e-05 Identities = 28/86 (32%), Positives = 44/86 (51%), Gaps = 2/86 (2%) Frame = +1 Query: 355 VATDNFDERNKLGEGGFGVVYKGI-LPDNEEIAVKRLSQSSRQGIEELK-NELVLVAKLQ 528 VA F + K+G G + VYKG+ +A+K + S +G E+ L+ +L+ Sbjct: 2 VAPSQFKQLEKVGNGTYATVYKGLNKTTGVYVALKEVKLDSEEGTPSTAIREISLMKELK 61 Query: 529 HKNLVRLLGVCLEEQEKLLAYEYMPN 606 H N+VRL V E + L +E+M N Sbjct: 62 HDNIVRLFDVIHTENKLTLVFEFMDN 87
>CDC2_CAEEL (P34556) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) Length = 332 Score = 47.8 bits (112), Expect = 3e-05 Identities = 28/82 (34%), Positives = 49/82 (59%), Gaps = 3/82 (3%) Frame = +1 Query: 364 DNFDERNKLGEGGFGVVYKG-ILPDNEEIAVKRLS-QSSRQGIEELK-NELVLVAKLQHK 534 ++F + K+GEG +GVVYKG N +A+K++ +S +G+ E+ L+ +LQH Sbjct: 20 NDFTKLEKIGEGTYGVVYKGKNRRTNAMVAMKKIRLESEDEGVPSTAVREISLLKELQHP 79 Query: 535 NLVRLLGVCLEEQEKLLAYEYM 600 N+V L V ++E L +E++ Sbjct: 80 NVVGLEAVIMQENRLFLIFEFL 101
>CDC7_SCHPO (P41892) Cell division control protein 7 (EC 2.7.11.1)| Length = 1062 Score = 47.8 bits (112), Expect = 3e-05 Identities = 28/82 (34%), Positives = 45/82 (54%), Gaps = 3/82 (3%) Frame = +1 Query: 388 LGEGGFGVVYKGI-LPDNEEIAVKR--LSQSSRQGIEELKNELVLVAKLQHKNLVRLLGV 558 LG+G FG VY+G+ + + E +AVK+ LS+ + + +K E+ L+ L H N+V+ G Sbjct: 15 LGKGAFGAVYRGLNIKNGETVAVKKVKLSKMLKSDLSVIKMEIDLLKNLDHPNIVKYRGS 74 Query: 559 CLEEQEKLLAYEYMPNKSLDTI 624 + EY N SL +I Sbjct: 75 YQTNDSLCIILEYCENGSLRSI 96
>PHO85_YEAST (P17157) Negative regulator of the PHO system (EC 2.7.11.22)| (Serine/threonine-protein kinase PHO85) Length = 305 Score = 47.4 bits (111), Expect = 4e-05 Identities = 27/85 (31%), Positives = 45/85 (52%), Gaps = 2/85 (2%) Frame = +1 Query: 358 ATDNFDERNKLGEGGFGVVYKGI-LPDNEEIAVKRLSQSSRQGIEELK-NELVLVAKLQH 531 ++ F + KLG G + VYKG+ +A+K + S +G E+ L+ +L+H Sbjct: 3 SSSQFKQLEKLGNGTYATVYKGLNKTTGVYVALKEVKLDSEEGTPSTAIREISLMKELKH 62 Query: 532 KNLVRLLGVCLEEQEKLLAYEYMPN 606 +N+VRL V E + L +E+M N Sbjct: 63 ENIVRLYDVIHTENKLTLVFEFMDN 87
>M3K11_HUMAN (Q16584) Mitogen-activated protein kinase kinase kinase 11 (EC| 2.7.11.25) (Mixed lineage kinase 3) (Src-homology 3 domain-containing proline-rich kinase) Length = 847 Score = 47.4 bits (111), Expect = 4e-05 Identities = 32/84 (38%), Positives = 40/84 (47%), Gaps = 4/84 (4%) Frame = +1 Query: 388 LGEGGFGVVYKGILPDNEEIAVKRLSQSSRQGI----EELKNELVLVAKLQHKNLVRLLG 555 +G GGFG VY+G E +AVK Q + I E ++ E L A L H N++ L Sbjct: 123 IGIGGFGKVYRGSWR-GELVAVKAARQDPDEDISVTAESVRQEARLFAMLAHPNIIALKA 181 Query: 556 VCLEEQEKLLAYEYMPNKSLDTIL 627 VCLEE L EY L L Sbjct: 182 VCLEEPNLCLVMEYAAGGPLSRAL 205
>MERTK_MOUSE (Q60805) Proto-oncogene tyrosine-protein kinase MER precursor (EC| 2.7.10.1) (C-mer) (Receptor tyrosine kinase MerTK) Length = 994 Score = 47.0 bits (110), Expect = 5e-05 Identities = 27/66 (40%), Positives = 40/66 (60%), Gaps = 6/66 (9%) Frame = +1 Query: 388 LGEGGFGVVYKGILPD----NEEIAVK--RLSQSSRQGIEELKNELVLVAKLQHKNLVRL 549 LGEG FG V +G L ++++AVK +L S++ IEE +E + H N++RL Sbjct: 588 LGEGEFGSVMEGNLKQEDGTSQKVAVKTMKLDNFSQREIEEFLSEAACMKDFNHPNVIRL 647 Query: 550 LGVCLE 567 LGVC+E Sbjct: 648 LGVCIE 653
>7LESS_DROME (P13368) Protein sevenless (EC 2.7.10.1)| Length = 2554 Score = 47.0 bits (110), Expect = 5e-05 Identities = 28/76 (36%), Positives = 45/76 (59%), Gaps = 5/76 (6%) Frame = +1 Query: 388 LGEGGFGVVYKGILP--DNEE---IAVKRLSQSSRQGIEELKNELVLVAKLQHKNLVRLL 552 LG G FG VY+G L D+EE +A+K L + + + EL E L++ +H+N+V L+ Sbjct: 2215 LGSGAFGEVYEGQLKTEDSEEPQRVAIKSLRKGASE-FAELLQEAQLMSNFKHENIVCLV 2273 Query: 553 GVCLEEQEKLLAYEYM 600 G+C + + L E+M Sbjct: 2274 GICFDTESISLIMEHM 2289
>PHO85_DEBHA (Q6BRY2) Negative regulator of the PHO system (EC 2.7.11.22)| (Serine/threonine-protein kinase PHO85) Length = 330 Score = 47.0 bits (110), Expect = 5e-05 Identities = 27/83 (32%), Positives = 45/83 (54%), Gaps = 2/83 (2%) Frame = +1 Query: 358 ATDNFDERNKLGEGGFGVVYKGILPDNEE-IAVKRLSQSSRQGIEELK-NELVLVAKLQH 531 ++ F + KLGEG + VYKG N + +A+K ++ S +G E+ L+ +L H Sbjct: 4 SSSQFQQLEKLGEGTYATVYKGRNRTNGQLVALKEINLDSEEGTPSTAIREISLMKELDH 63 Query: 532 KNLVRLLGVCLEEQEKLLAYEYM 600 +N+V L V E + L +E+M Sbjct: 64 ENIVTLYDVIHTENKLTLVFEFM 86
>BUR1_YEAST (P23293) Serine/threonine-protein kinase BUR1 (EC 2.7.11.22) (EC| 2.7.11.23) (Suppressor of GPA1-Vall50 mutation protein 1) (Bypass UAS requirement protein 1) Length = 657 Score = 47.0 bits (110), Expect = 5e-05 Identities = 32/106 (30%), Positives = 57/106 (53%), Gaps = 7/106 (6%) Frame = +1 Query: 256 KSTPA----RKTSLSYPTIPEXXXXXXXXXXXXXTLRVATDNFDERNKLGEGGFGVVYKG 423 KSTPA KT+L+Y + + V +++ E KLG+G FG VYKG Sbjct: 24 KSTPAIQRDAKTNLTYIKLRKRSSEKVYGCT------VFQNHYREDEKLGQGTFGEVYKG 77 Query: 424 I-LPDNEEIAVKRLSQSSRQGIEEL--KNELVLVAKLQHKNLVRLL 552 I L ++A+K++ S + + + + E+ ++ +L HKN+++L+ Sbjct: 78 IHLETQRQVAMKKIIVSVEKDLFPITAQREITILKRLNHKNIIKLI 123
>CDK2_XENLA (P23437) Cell division protein kinase 2 (EC 2.7.11.22) (CDC2| homolog Eg1 protein kinase) Length = 297 Score = 47.0 bits (110), Expect = 5e-05 Identities = 28/82 (34%), Positives = 48/82 (58%), Gaps = 3/82 (3%) Frame = +1 Query: 364 DNFDERNKLGEGGFGVVYKGILPDNEEI-AVKRLS-QSSRQGIEELK-NELVLVAKLQHK 534 +NF + K+GEG +GVVYK + EI A+K++ + +G+ E+ L+ +L H Sbjct: 2 ENFQKVEKIGEGTYGVVYKARNRETGEIVALKKIRLDTETEGVPSTAIREISLLKELNHP 61 Query: 535 NLVRLLGVCLEEQEKLLAYEYM 600 N+V+LL V E + L +E++ Sbjct: 62 NIVKLLDVIHTENKLYLVFEFL 83
>ROR1_MOUSE (Q9Z139) Tyrosine-protein kinase transmembrane receptor ROR1| precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase, receptor-related 1) (mROR1) Length = 937 Score = 47.0 bits (110), Expect = 5e-05 Identities = 32/87 (36%), Positives = 46/87 (52%), Gaps = 6/87 (6%) Frame = +1 Query: 385 KLGEGGFGVVYKG--ILPDNEE---IAVKRLSQ-SSRQGIEELKNELVLVAKLQHKNLVR 546 +LGE FG +YKG LP + +A+K L ++ Q E + E L+A+L H N+V Sbjct: 478 ELGECTFGKIYKGHLYLPGMDHAQLVAIKTLKDYNNPQQWTEFQQEASLMAELHHPNIVC 537 Query: 547 LLGVCLEEQEKLLAYEYMPNKSLDTIL 627 LLG +EQ + +EYM L L Sbjct: 538 LLGAVTQEQPVCMLFEYMNQGDLHEFL 564
>ERBB3_PONPY (Q5RB22) Receptor tyrosine-protein kinase erbB-3 precursor (EC| 2.7.10.1) Length = 1342 Score = 47.0 bits (110), Expect = 5e-05 Identities = 27/82 (32%), Positives = 46/82 (56%), Gaps = 6/82 (7%) Frame = +1 Query: 388 LGEGGFGVVYKGI-LPDNEEIAVKRL-----SQSSRQGIEELKNELVLVAKLQHKNLVRL 549 LG G FG V+KG+ +P+ E I + +S RQ + + + ++ + L H ++VRL Sbjct: 715 LGSGVFGTVHKGVWIPEGESIKIPVCIKVIEDKSGRQSFQAVTDHMLAIGSLDHAHIVRL 774 Query: 550 LGVCLEEQEKLLAYEYMPNKSL 615 LG+C +L+ +Y+P SL Sbjct: 775 LGLCPGSSLQLVT-QYLPLGSL 795
>ERBB3_HUMAN (P21860) Receptor tyrosine-protein kinase erbB-3 precursor (EC| 2.7.10.1) (c-erbB3) (Tyrosine kinase-type cell surface receptor HER3) Length = 1342 Score = 47.0 bits (110), Expect = 5e-05 Identities = 27/82 (32%), Positives = 46/82 (56%), Gaps = 6/82 (7%) Frame = +1 Query: 388 LGEGGFGVVYKGI-LPDNEEIAVKRL-----SQSSRQGIEELKNELVLVAKLQHKNLVRL 549 LG G FG V+KG+ +P+ E I + +S RQ + + + ++ + L H ++VRL Sbjct: 715 LGSGVFGTVHKGVWIPEGESIKIPVCIKVIEDKSGRQSFQAVTDHMLAIGSLDHAHIVRL 774 Query: 550 LGVCLEEQEKLLAYEYMPNKSL 615 LG+C +L+ +Y+P SL Sbjct: 775 LGLCPGSSLQLVT-QYLPLGSL 795
>SRC64_DROME (P00528) Tyrosine-protein kinase Src64B (EC 2.7.10.2) (Dsrc64)| Length = 552 Score = 47.0 bits (110), Expect = 5e-05 Identities = 27/77 (35%), Positives = 41/77 (53%) Frame = +1 Query: 385 KLGEGGFGVVYKGILPDNEEIAVKRLSQSSRQGIEELKNELVLVAKLQHKNLVRLLGVCL 564 KLG G FG V+ G ++ ++AVK L + + L+ E ++ K +H LV L VC Sbjct: 289 KLGRGNFGEVFYGKWRNSIDVAVKTLREGTMSTAAFLQ-EAAIMKKFRHNRLVALYAVCS 347 Query: 565 EEQEKLLAYEYMPNKSL 615 +E+ + EYM SL Sbjct: 348 QEEPIYIVQEYMSKGSL 364
>EGFR_MOUSE (Q01279) Epidermal growth factor receptor precursor (EC 2.7.10.1)| Length = 1210 Score = 46.6 bits (109), Expect = 6e-05 Identities = 28/84 (33%), Positives = 51/84 (60%), Gaps = 6/84 (7%) Frame = +1 Query: 370 FDERNKLGEGGFGVVYKGI-LPDNEEI----AVKRLSQS-SRQGIEELKNELVLVAKLQH 531 F + LG G FG VYKG+ +P+ E++ A+K L ++ S + +E+ +E ++A + + Sbjct: 714 FKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDN 773 Query: 532 KNLVRLLGVCLEEQEKLLAYEYMP 603 ++ RLLG+CL +L+ + MP Sbjct: 774 PHVCRLLGICLTSTVQLIT-QLMP 796
>EGFR_HUMAN (P00533) Epidermal growth factor receptor precursor (EC 2.7.10.1)| (Receptor tyrosine-protein kinase ErbB-1) Length = 1210 Score = 46.6 bits (109), Expect = 6e-05 Identities = 28/84 (33%), Positives = 51/84 (60%), Gaps = 6/84 (7%) Frame = +1 Query: 370 FDERNKLGEGGFGVVYKGI-LPDNEEI----AVKRLSQS-SRQGIEELKNELVLVAKLQH 531 F + LG G FG VYKG+ +P+ E++ A+K L ++ S + +E+ +E ++A + + Sbjct: 712 FKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDN 771 Query: 532 KNLVRLLGVCLEEQEKLLAYEYMP 603 ++ RLLG+CL +L+ + MP Sbjct: 772 PHVCRLLGICLTSTVQLIT-QLMP 794
>SRK2_SPOLA (P42688) Tyrosine-protein kinase SRK2 (EC 2.7.10.2) (Fragment)| Length = 362 Score = 46.6 bits (109), Expect = 6e-05 Identities = 28/87 (32%), Positives = 45/87 (51%) Frame = +1 Query: 355 VATDNFDERNKLGEGGFGVVYKGILPDNEEIAVKRLSQSSRQGIEELKNELVLVAKLQHK 534 ++ D+ KLG G FG VY+G+ ++ +AVK L + Q L E ++ KL+H Sbjct: 90 ISRDSITLIRKLGAGQFGEVYQGLWNNSTPVAVKTLKAGTMQPAAFLA-EAQIMKKLRHP 148 Query: 535 NLVRLLGVCLEEQEKLLAYEYMPNKSL 615 L++L VC + + + E M SL Sbjct: 149 KLIQLYAVCTQGEPVYIITELMSKGSL 175
>M3K5_MOUSE (O35099) Mitogen-activated protein kinase kinase kinase 5 (EC| 2.7.11.25) (MAPK/ERK kinase kinase 5) (MEK kinase 5) (MEKK 5) (Apoptosis signal-regulating kinase 1) (ASK-1) Length = 1380 Score = 46.6 bits (109), Expect = 6e-05 Identities = 29/89 (32%), Positives = 46/89 (51%), Gaps = 1/89 (1%) Frame = +1 Query: 364 DNFDERNKLGEGGFGVVYKGI-LPDNEEIAVKRLSQSSRQGIEELKNELVLVAKLQHKNL 540 D +R LG+G +G+VY G L + IA+K + + + + L E+ L L+HKN+ Sbjct: 685 DENGDRVVLGKGTYGIVYAGRDLSNQVRIAIKEIPERDSRYSQPLHEEIALHKHLKHKNI 744 Query: 541 VRLLGVCLEEQEKLLAYEYMPNKSLDTIL 627 V+ LG E + E +P SL +L Sbjct: 745 VQYLGSFSENGFIKIFMEQVPGGSLSALL 773
>SRK4_SPOLA (P42690) Tyrosine-protein kinase isoform SRK4 (EC 2.7.10.2)| Length = 506 Score = 46.6 bits (109), Expect = 6e-05 Identities = 26/76 (34%), Positives = 41/76 (53%) Frame = +1 Query: 388 LGEGGFGVVYKGILPDNEEIAVKRLSQSSRQGIEELKNELVLVAKLQHKNLVRLLGVCLE 567 LG G FG V++G+ +AVK L + IEE E ++ +L+H L++L VC + Sbjct: 246 LGAGQFGEVWEGLWNGTTSVAVKTLKPGT-MSIEEFLEEASIMKQLRHPKLIQLYAVCTK 304 Query: 568 EQEKLLAYEYMPNKSL 615 E+ + E M + SL Sbjct: 305 EEPIYIVTELMKHGSL 320
>ERBB_ALV (P00534) Tyrosine-protein kinase transforming protein erbB (EC| 2.7.10.1) Length = 634 Score = 46.6 bits (109), Expect = 6e-05 Identities = 28/84 (33%), Positives = 51/84 (60%), Gaps = 6/84 (7%) Frame = +1 Query: 370 FDERNKLGEGGFGVVYKGI-LPDNEEI----AVKRLSQS-SRQGIEELKNELVLVAKLQH 531 F + LG G FG VYKG+ +P+ E++ A+K L ++ S + +E+ +E ++A + + Sbjct: 132 FKKVKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDN 191 Query: 532 KNLVRLLGVCLEEQEKLLAYEYMP 603 ++ RLLG+CL +L+ + MP Sbjct: 192 PHVCRLLGICLTSTVQLIT-QLMP 214
>CDC21_MEDSA (P24923) Cell division control protein 2 homolog 1 (EC 2.7.11.22)| (EC 2.7.11.23) (Fragment) Length = 291 Score = 46.6 bits (109), Expect = 6e-05 Identities = 29/75 (38%), Positives = 42/75 (56%), Gaps = 3/75 (4%) Frame = +1 Query: 385 KLGEGGFGVVYKGI-LPDNEEIAVK--RLSQSSRQGIEELKNELVLVAKLQHKNLVRLLG 555 K+GEG +GVVYK NE IA+K RL Q E+ L+ ++QH+N+VRL Sbjct: 6 KIGEGTYGVVYKARDRVTNETIALKKIRLEQEDEGVPSTAIREISLLKEMQHRNIVRLQD 65 Query: 556 VCLEEQEKLLAYEYM 600 V ++ L +EY+ Sbjct: 66 VVHSDKRLYLVFEYL 80
>TESK1_RAT (Q63572) Dual specificity testis-specific protein kinase 1 (EC| 2.7.12.1) (Testicular protein kinase 1) Length = 628 Score = 46.6 bits (109), Expect = 6e-05 Identities = 26/88 (29%), Positives = 49/88 (55%) Frame = +1 Query: 364 DNFDERNKLGEGGFGVVYKGILPDNEEIAVKRLSQSSRQGIEELKNELVLVAKLQHKNLV 543 D+FD K+G G F VYK + ++ V ++++ L+ E+ L+ +L+H N++ Sbjct: 50 DDFDCAEKIGAGFFSEVYKVRHRQSGQVMVLKMNKLPSNRSNTLR-EVQLMNRLRHPNIL 108 Query: 544 RLLGVCLEEQEKLLAYEYMPNKSLDTIL 627 R +GVC+ + + EYM +L+ +L Sbjct: 109 RFMGVCVHQGQLHALTEYMNGGTLEQLL 136
>PHO85_CANAL (Q9HGY5) Negative regulator of the PHO system (EC 2.7.11.22)| (Serine/threonine-protein kinase PHO85) (CaPHO85) Length = 326 Score = 46.6 bits (109), Expect = 6e-05 Identities = 28/83 (33%), Positives = 43/83 (51%), Gaps = 2/83 (2%) Frame = +1 Query: 358 ATDNFDERNKLGEGGFGVVYKGI-LPDNEEIAVKRLSQSSRQGIEELK-NELVLVAKLQH 531 ++ F + KLGEG + VYKG +A+K +S S +G E+ L+ +L H Sbjct: 4 SSSQFQQLEKLGEGTYATVYKGRNRATGALVALKEISLDSEEGTPSTAIREISLMKELDH 63 Query: 532 KNLVRLLGVCLEEQEKLLAYEYM 600 +N+V L V E + L +EYM Sbjct: 64 ENIVTLYDVIHTENKLTLVFEYM 86
>CDC2_DROME (P23572) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) Length = 297 Score = 46.6 bits (109), Expect = 6e-05 Identities = 30/96 (31%), Positives = 57/96 (59%), Gaps = 6/96 (6%) Frame = +1 Query: 364 DNFDERNKLGEGGFGVVYKG-ILPDNEEIAVKRLS-QSSRQGIEELK-NELVLVAKLQHK 534 ++F++ K+GEG +GVVYKG + +A+K++ +S +G+ E+ L+ +L+H+ Sbjct: 2 EDFEKIEKIGEGTYGVVYKGRNRLTGQIVAMKKIRLESDDEGVPSTAIREISLLKELKHE 61 Query: 535 NLVRLLGVCLEEQEKLLAYEYMP---NKSLDTILFD 633 N+V L V +EE L +E++ K +D++ D Sbjct: 62 NIVCLEDVLMEENRIYLIFEFLSMDLKKYMDSLPVD 97
>CC2H2_TRYBB (P54665) Cell division control protein 2 homolog 2 (EC 2.7.11.22)| Length = 345 Score = 46.6 bits (109), Expect = 6e-05 Identities = 31/84 (36%), Positives = 44/84 (52%), Gaps = 5/84 (5%) Frame = +1 Query: 364 DNFDERNKLGEGGFGVVYKGILPDN---EEIAVKRLSQSSRQG--IEELKNELVLVAKLQ 528 D + K+GEG +G+VYK DN +A+KR+ G E+ L+ +L Sbjct: 44 DRYSRIEKVGEGSYGIVYK--CHDNFTGRTVAMKRIPLIVNDGGVPSTAVREVSLLRELN 101 Query: 529 HKNLVRLLGVCLEEQEKLLAYEYM 600 H +VRLL V L E + LL +EYM Sbjct: 102 HPYVVRLLDVVLHEAKLLLIFEYM 125
>M3K5_HUMAN (Q99683) Mitogen-activated protein kinase kinase kinase 5 (EC| 2.7.11.25) (MAPK/ERK kinase kinase 5) (MEK kinase 5) (MEKK 5) (Apoptosis signal-regulating kinase 1) (ASK-1) Length = 1374 Score = 46.6 bits (109), Expect = 6e-05 Identities = 29/89 (32%), Positives = 46/89 (51%), Gaps = 1/89 (1%) Frame = +1 Query: 364 DNFDERNKLGEGGFGVVYKGI-LPDNEEIAVKRLSQSSRQGIEELKNELVLVAKLQHKNL 540 D +R LG+G +G+VY G L + IA+K + + + + L E+ L L+HKN+ Sbjct: 678 DENGDRVVLGKGTYGIVYAGRDLSNQVRIAIKEIPERDSRYSQPLHEEIALHKHLKHKNI 737 Query: 541 VRLLGVCLEEQEKLLAYEYMPNKSLDTIL 627 V+ LG E + E +P SL +L Sbjct: 738 VQYLGSFSENGFIKIFMEQVPGGSLSALL 766
>AURKC_MOUSE (O88445) Serine/threonine-protein kinase 13 (EC 2.7.11.1)| (Aurora/Ipl1/Eg2 protein 1) (Aurora-C) Length = 282 Score = 46.6 bits (109), Expect = 6e-05 Identities = 28/88 (31%), Positives = 47/88 (53%), Gaps = 4/88 (4%) Frame = +1 Query: 364 DNFDERNKLGEGGFGVVYKGILPDNEEIAVKRL---SQSSRQGIE-ELKNELVLVAKLQH 531 ++F+ LG G FG VY L +N I ++ S+ ++G+E +L+ E+ + A LQH Sbjct: 14 NDFEIGRPLGRGKFGRVYLARLKENHFIVALKVLFKSEIEKEGLEHQLRREVEIQAHLQH 73 Query: 532 KNLVRLLGVCLEEQEKLLAYEYMPNKSL 615 +N++RL ++ L EY P L Sbjct: 74 RNILRLYNYFYDDTRIYLILEYAPGGEL 101
>TESK1_MOUSE (O70146) Dual specificity testis-specific protein kinase 1 (EC| 2.7.12.1) (Testicular protein kinase 1) Length = 627 Score = 46.6 bits (109), Expect = 6e-05 Identities = 26/88 (29%), Positives = 49/88 (55%) Frame = +1 Query: 364 DNFDERNKLGEGGFGVVYKGILPDNEEIAVKRLSQSSRQGIEELKNELVLVAKLQHKNLV 543 D+FD K+G G F VYK + ++ V ++++ L+ E+ L+ +L+H N++ Sbjct: 50 DDFDCAEKIGAGFFSEVYKVRHRQSGQVMVLKMNKLPSNRSNTLR-EVQLMNRLRHPNIL 108 Query: 544 RLLGVCLEEQEKLLAYEYMPNKSLDTIL 627 R +GVC+ + + EYM +L+ +L Sbjct: 109 RFMGVCVHQGQLHALTEYMNGGTLEQLL 136
>ERBB_AVIER (P00535) Tyrosine-protein kinase transforming protein erbB (EC| 2.7.10.1) Length = 604 Score = 46.2 bits (108), Expect = 8e-05 Identities = 27/84 (32%), Positives = 51/84 (60%), Gaps = 6/84 (7%) Frame = +1 Query: 370 FDERNKLGEGGFGVVYKGI-LPDNEEI----AVKRLSQS-SRQGIEELKNELVLVAKLQH 531 F + LG G FG +YKG+ +P+ E++ A+K L ++ S + +E+ +E ++A + + Sbjct: 132 FKKVKVLGSGAFGTIYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDN 191 Query: 532 KNLVRLLGVCLEEQEKLLAYEYMP 603 ++ RLLG+CL +L+ + MP Sbjct: 192 PHVCRLLGICLTSTVQLIT-QLMP 214
>PHO85_YARLI (Q6C7U8) Negative regulator of the PHO system (EC 2.7.11.22)| (Serine/threonine-protein kinase PHO85) Length = 294 Score = 46.2 bits (108), Expect = 8e-05 Identities = 30/92 (32%), Positives = 48/92 (52%), Gaps = 5/92 (5%) Frame = +1 Query: 361 TDNFDERNKLGEGGFGVVYKGI-LPDNEEIAVKRLSQSSRQGIEELK-NELVLVAKLQHK 534 + F + KLGEG + VYKG + +A+K ++ S +G E+ L+ +L+H+ Sbjct: 4 SSQFQQLEKLGEGTYATVYKGRNRTTGQLVALKEINLDSEEGTPSTAIREISLMKELKHE 63 Query: 535 NLVRLLGVCLEEQEKLLAYEYMP---NKSLDT 621 N+V L V E + L +EYM K +DT Sbjct: 64 NIVTLYDVIHTENKLNLVFEYMDKDLKKFMDT 95
>PTK6_HUMAN (Q13882) Tyrosine-protein kinase 6 (EC 2.7.10.2) (Breast tumor| kinase) (Tyrosine-protein kinase BRK) Length = 451 Score = 46.2 bits (108), Expect = 8e-05 Identities = 27/90 (30%), Positives = 48/90 (53%) Frame = +1 Query: 364 DNFDERNKLGEGGFGVVYKGILPDNEEIAVKRLSQSSRQGIEELKNELVLVAKLQHKNLV 543 + F KLG G FG V++G+ D ++A+K +S+ + + L++E+ + KL+HK+++ Sbjct: 189 EEFTLCRKLGSGYFGEVFEGLWKDRVQVAIKVISRDNLLHQQMLQSEIQAMKKLRHKHIL 248 Query: 544 RLLGVCLEEQEKLLAYEYMPNKSLDTILFD 633 L V + E M SL +L D Sbjct: 249 ALYAVVSVGDPVYIITELMAKGSLLELLRD 278
>RYK_AVIR3 (P33497) Tyrosine-protein kinase transforming protein RYK (EC| 2.7.10.1) Length = 442 Score = 46.2 bits (108), Expect = 8e-05 Identities = 27/66 (40%), Positives = 38/66 (57%), Gaps = 6/66 (9%) Frame = +1 Query: 388 LGEGGFGVVYKGILPDNE----EIAVK--RLSQSSRQGIEELKNELVLVAKLQHKNLVRL 549 LGEG FG V +G L E ++AVK +L S + IEE +E + H N+++L Sbjct: 51 LGEGEFGSVMEGRLSQPEGTPQKVAVKTMKLDNFSHREIEEFLSEAACIKDFDHPNVIKL 110 Query: 550 LGVCLE 567 LGVC+E Sbjct: 111 LGVCIE 116
>VAB1_CAEEL (O61460) Ephrin receptor 1 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase Eph receptor) (Variable abnormal protein 1) Length = 1122 Score = 46.2 bits (108), Expect = 8e-05 Identities = 28/81 (34%), Positives = 42/81 (51%), Gaps = 1/81 (1%) Frame = +1 Query: 388 LGEGGFGVVYKGILPDNEEIAVKRL-SQSSRQGIEELKNELVLVAKLQHKNLVRLLGVCL 564 +G GG G Y+ E +A+K L S SS + E E ++ + H N++RL+GV Sbjct: 728 MGRGGGGGGYES--EPYETVAIKTLKSGSSAKAKAEFLTEATIMGQFSHPNVIRLIGVVT 785 Query: 565 EEQEKLLAYEYMPNKSLDTIL 627 + ++ EYM N SLD L Sbjct: 786 SAEPVMIVAEYMANGSLDQFL 806
>ROS_HUMAN (P08922) Proto-oncogene tyrosine-protein kinase ROS precursor (EC| 2.7.10.1) (c-ros-1) Length = 2347 Score = 46.2 bits (108), Expect = 8e-05 Identities = 33/89 (37%), Positives = 47/89 (52%), Gaps = 9/89 (10%) Frame = +1 Query: 388 LGEGGFGVVYKGILPD-------NEEIAVKRLSQSS--RQGIEELKNELVLVAKLQHKNL 540 LG G FG VY+G D ++AVK L + S ++ IE LK E L++K H N+ Sbjct: 1951 LGSGAFGEVYEGTAVDILGVGSGEIKVAVKTLKKGSTDQEKIEFLK-EAHLMSKFNHPNI 2009 Query: 541 VRLLGVCLEEQEKLLAYEYMPNKSLDTIL 627 ++ LGVCL + + + E M L T L Sbjct: 2010 LKQLGVCLLNEPQYIILELMEGGDLLTYL 2038
>CC2H1_TRYBB (P38973) Cell division control protein 2 homolog 1 (EC 2.7.11.22)| Length = 301 Score = 46.2 bits (108), Expect = 8e-05 Identities = 26/80 (32%), Positives = 47/80 (58%), Gaps = 3/80 (3%) Frame = +1 Query: 370 FDERNKLGEGGFGVVYKGI-LPDNEEIAVKRLS-QSSRQGIE-ELKNELVLVAKLQHKNL 540 ++ K+GEG +GVV++ + +AVKR+ + +G+ E+ ++ +L+H+N+ Sbjct: 5 YERLQKIGEGSYGVVFRARDVTTGTIVAVKRIRLEKEEEGVPCTAIREISILKELRHENI 64 Query: 541 VRLLGVCLEEQEKLLAYEYM 600 VRLL VC E+ L +E M Sbjct: 65 VRLLDVCHSEKRLTLVFECM 84
>M3K6_HUMAN (O95382) Mitogen-activated protein kinase kinase kinase 6 (EC| 2.7.11.25) Length = 1011 Score = 46.2 bits (108), Expect = 8e-05 Identities = 29/85 (34%), Positives = 45/85 (52%), Gaps = 1/85 (1%) Frame = +1 Query: 376 ERNKLGEGGFGVVYKGILPDNE-EIAVKRLSQSSRQGIEELKNELVLVAKLQHKNLVRLL 552 ER LG+G +GVVY G IA+K + + + + L E+ L +L+HKN+VR L Sbjct: 373 ERLVLGKGTYGVVYAGRDRHTRVRIAIKEIPERDSRFSQPLHEEIALHRRLRHKNIVRYL 432 Query: 553 GVCLEEQEKLLAYEYMPNKSLDTIL 627 G + + E +P SL ++L Sbjct: 433 GSASQGGYLKIFMEEVPGGSLSSLL 457
>EPHA1_MOUSE (Q60750) Ephrin type-A receptor 1 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor ESK) Length = 977 Score = 46.2 bits (108), Expect = 8e-05 Identities = 27/85 (31%), Positives = 45/85 (52%), Gaps = 5/85 (5%) Frame = +1 Query: 388 LGEGGFGVVYKGIL----PDNEEIAVKRLSQSSRQGI-EELKNELVLVAKLQHKNLVRLL 552 +GEG FG VY+G L D + +A+K L +S G E ++ + H +++RL Sbjct: 631 IGEGEFGEVYRGALRLPSQDCKTVAIKTLKDTSPDGYWWNFLREATIMGQFNHPHILRLE 690 Query: 553 GVCLEEQEKLLAYEYMPNKSLDTIL 627 GV + + ++ E+M N +LD L Sbjct: 691 GVITKRKPIMIITEFMENGALDAFL 715
>SRK1_SPOLA (P42686) Tyrosine-protein kinase isoform SRK1 (EC 2.7.10.2)| Length = 505 Score = 46.2 bits (108), Expect = 8e-05 Identities = 25/77 (32%), Positives = 41/77 (53%) Frame = +1 Query: 385 KLGEGGFGVVYKGILPDNEEIAVKRLSQSSRQGIEELKNELVLVAKLQHKNLVRLLGVCL 564 +LG G FG V++G+ +AVK L + +EE E ++ +L+H L++L VC Sbjct: 245 RLGAGQFGEVWEGLWNGTTSVAVKTLKPGT-MSVEEFLQEASIMKRLRHPKLIQLYAVCT 303 Query: 565 EEQEKLLAYEYMPNKSL 615 +E+ + E M SL Sbjct: 304 KEEPIYIVTELMKYGSL 320
>7LESS_DROVI (P20806) Protein sevenless (EC 2.7.10.1)| Length = 2594 Score = 46.2 bits (108), Expect = 8e-05 Identities = 27/75 (36%), Positives = 43/75 (57%), Gaps = 4/75 (5%) Frame = +1 Query: 388 LGEGGFGVVYKGILPDNEEIAVKRLS-QSSRQGIEE---LKNELVLVAKLQHKNLVRLLG 555 LG G FG VY+G L +E +R++ +S R+G E L E L++ +H+N+V L+G Sbjct: 2230 LGSGAFGEVYEGQLQAEDEAQPQRVAIKSLRKGASEFAELLQEAQLMSNFKHENIVCLIG 2289 Query: 556 VCLEEQEKLLAYEYM 600 +C + L E+M Sbjct: 2290 ICCDTDSISLIMEHM 2304
>NTRK3_PIG (P24786) NT-3 growth factor receptor precursor (EC 2.7.10.1)| (Neurotrophic tyrosine kinase receptor type 3) (TrkC tyrosine kinase) (GP145-TrkC) (Trk-C) Length = 825 Score = 46.2 bits (108), Expect = 8e-05 Identities = 26/89 (29%), Positives = 47/89 (52%), Gaps = 6/89 (6%) Frame = +1 Query: 379 RNKLGEGGFGVVYKG----ILPDNEE--IAVKRLSQSSRQGIEELKNELVLVAKLQHKNL 540 + +LGEG FG V+ + P + +AVK L + ++ + E L+ LQH+++ Sbjct: 541 KRELGEGAFGKVFLAECYNLSPTKVKMLVAVKALKDPTLAARKDFQREAELLTNLQHEHI 600 Query: 541 VRLLGVCLEEQEKLLAYEYMPNKSLDTIL 627 V+ GVC + ++ +EYM + L+ L Sbjct: 601 VKFYGVCGDGDPLIMVFEYMKHGDLNKFL 629
>CDC15_YEAST (P27636) Cell division control protein 15 (EC 2.7.11.1)| Length = 974 Score = 45.8 bits (107), Expect = 1e-04 Identities = 23/81 (28%), Positives = 43/81 (53%), Gaps = 1/81 (1%) Frame = +1 Query: 388 LGEGGFGVVYKGILPDNEEI-AVKRLSQSSRQGIEELKNELVLVAKLQHKNLVRLLGVCL 564 +G G +GVVYK I +++ A+K + + + + ++ E+ L+ L H N+V+ G Sbjct: 31 IGRGSYGVVYKAINKHTDQVVAIKEVVYENDEELNDIMAEISLLKNLNHNNIVKYHGFIR 90 Query: 565 EEQEKLLAYEYMPNKSLDTIL 627 + E + EY N SL ++ Sbjct: 91 KSYELYILLEYCANGSLRRLI 111
>ROR1_HUMAN (Q01973) Tyrosine-protein kinase transmembrane receptor ROR1| precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase, receptor-related 1) Length = 937 Score = 45.8 bits (107), Expect = 1e-04 Identities = 31/87 (35%), Positives = 46/87 (52%), Gaps = 6/87 (6%) Frame = +1 Query: 385 KLGEGGFGVVYKG--ILPDNEE---IAVKRLSQ-SSRQGIEELKNELVLVAKLQHKNLVR 546 +LGE FG +YKG LP + +A+K L ++ Q E + E L+A+L H N+V Sbjct: 478 ELGECAFGKIYKGHLYLPGMDHAQLVAIKTLKDYNNPQQWMEFQQEASLMAELHHPNIVC 537 Query: 547 LLGVCLEEQEKLLAYEYMPNKSLDTIL 627 LLG +EQ + +EY+ L L Sbjct: 538 LLGAVTQEQPVCMLFEYINQGDLHEFL 564
>IGF1R_MOUSE (Q60751) Insulin-like growth factor 1 receptor precursor (EC| 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain] Length = 1373 Score = 45.8 bits (107), Expect = 1e-04 Identities = 34/99 (34%), Positives = 54/99 (54%), Gaps = 8/99 (8%) Frame = +1 Query: 355 VATDNFDERNKLGEGGFGVVY----KGILPDNEE--IAVKRLSQ--SSRQGIEELKNELV 510 VA + +LG+G FG+VY KG++ D E +A+K +++ S R+ IE L NE Sbjct: 995 VAREKITMNRELGQGSFGMVYEGVAKGVVKDEPETRVAIKTVNEAASMRERIEFL-NEAS 1053 Query: 511 LVAKLQHKNLVRLLGVCLEEQEKLLAYEYMPNKSLDTIL 627 ++ + ++VRLLGV + Q L+ E M L + L Sbjct: 1054 VMKEFNCHHVVRLLGVVSQGQPTLVIMELMTRGDLKSYL 1092
>WRK19_ARATH (Q9SZ67) Probable WRKY transcription factor 19 (WRKY DNA-binding| protein 19) Length = 1895 Score = 45.8 bits (107), Expect = 1e-04 Identities = 25/81 (30%), Positives = 43/81 (53%), Gaps = 5/81 (6%) Frame = +1 Query: 388 LGEGGFGVVYKGILPDNEEIAVKRLS-----QSSRQGIEELKNELVLVAKLQHKNLVRLL 552 LG G G VY+GI D + A K +S + + I++++ + L+++LQH+N+VR Sbjct: 1632 LGRGSLGSVYEGISADGDFFAFKEVSLLDQGSQAHEWIQQVEGGIALLSQLQHQNIVRYR 1691 Query: 553 GVCLEEQEKLLAYEYMPNKSL 615 G +E + E + SL Sbjct: 1692 GTTKDESNLYIFLELVTQGSL 1712
>ALK_HUMAN (Q9UM73) ALK tyrosine kinase receptor precursor (EC 2.7.10.1)| (Anaplastic lymphoma kinase) (CD246 antigen) Length = 1620 Score = 45.8 bits (107), Expect = 1e-04 Identities = 28/87 (32%), Positives = 45/87 (51%), Gaps = 7/87 (8%) Frame = +1 Query: 388 LGEGGFGVVYKGIL------PDNEEIAVKRLSQ-SSRQGIEELKNELVLVAKLQHKNLVR 546 LG G FG VY+G + P ++AVK L + S Q + E ++++K H+N+VR Sbjct: 1122 LGHGAFGEVYEGQVSGMPNDPSPLQVAVKTLPEVCSEQDELDFLMEALIISKFNHQNIVR 1181 Query: 547 LLGVCLEEQEKLLAYEYMPNKSLDTIL 627 +GV L+ + + E M L + L Sbjct: 1182 CIGVSLQSLPRFILLELMAGGDLKSFL 1208
>ABL_DROME (P00522) Tyrosine-protein kinase Abl (EC 2.7.10.2) (Abelson| protein) (D-ash) Length = 1620 Score = 45.8 bits (107), Expect = 1e-04 Identities = 24/80 (30%), Positives = 46/80 (57%), Gaps = 1/80 (1%) Frame = +1 Query: 379 RNKLGEGGFGVVYKGILPD-NEEIAVKRLSQSSRQGIEELKNELVLVAKLQHKNLVRLLG 555 ++KLG G +G VY+ + +AVK L + + +++ E ++ +++H NLV+L+G Sbjct: 374 KHKLGGGQYGEVYEAVWKRYGNTVAVKTLKEDT-MALKDFLEEAAIMKEMKHPNLVQLIG 432 Query: 556 VCLEEQEKLLAYEYMPNKSL 615 VC E + E+M + +L Sbjct: 433 VCTREPPFYIITEFMSHGNL 452
>TAOK2_XENLA (Q6GPK9) Serine/threonine-protein kinase TAO2 (EC 2.7.11.1)| (Thousand and one amino acid protein 2) Length = 1025 Score = 45.8 bits (107), Expect = 1e-04 Identities = 27/89 (30%), Positives = 45/89 (50%), Gaps = 4/89 (4%) Frame = +1 Query: 370 FDERNKLGEGGFGVVYKGI-LPDNEEIAVKRLSQSSRQGIE---ELKNELVLVAKLQHKN 537 F + ++G G FG VY + +NE +A+K++S S +Q E ++ E+ + KL+H N Sbjct: 28 FADLREIGHGSFGAVYFARDIRNNEVVAIKKMSYSGKQSNEKWQDIIKEVKFLQKLRHPN 87 Query: 538 LVRLLGVCLEEQEKLLAYEYMPNKSLDTI 624 + G L E L EY + D + Sbjct: 88 TIEYKGCYLREHTAWLVMEYCLGSASDLL 116
>CDC2H_PLACH (Q4Y4B1) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) Length = 288 Score = 45.8 bits (107), Expect = 1e-04 Identities = 24/74 (32%), Positives = 44/74 (59%), Gaps = 2/74 (2%) Frame = +1 Query: 385 KLGEGGFGVVYKGILPDNEEIAVKRLS-QSSRQGIEELK-NELVLVAKLQHKNLVRLLGV 558 K+GEG +GVVYK D E A+K++ + +GI E+ ++ +L+H N+V+L V Sbjct: 9 KIGEGTYGVVYKAQNSDGESFALKKIRLEKEDEGIPSTAIREISILKELRHSNIVKLYDV 68 Query: 559 CLEEQEKLLAYEYM 600 ++ +L +E++ Sbjct: 69 IHAKKRLILVFEHL 82
>CDC2H_PLABA (Q4Z6R1) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) Length = 288 Score = 45.8 bits (107), Expect = 1e-04 Identities = 24/74 (32%), Positives = 44/74 (59%), Gaps = 2/74 (2%) Frame = +1 Query: 385 KLGEGGFGVVYKGILPDNEEIAVKRLS-QSSRQGIEELK-NELVLVAKLQHKNLVRLLGV 558 K+GEG +GVVYK D E A+K++ + +GI E+ ++ +L+H N+V+L V Sbjct: 9 KIGEGTYGVVYKAQNSDGESFALKKIRLEKEDEGIPSTAIREISILKELRHSNIVKLYDV 68 Query: 559 CLEEQEKLLAYEYM 600 ++ +L +E++ Sbjct: 69 IHAKKRLILVFEHL 82
>RTK2_GEOCY (P42159) Class II receptor tyrosine kinase (EC 2.7.10.1) (GCTK)| Length = 605 Score = 45.8 bits (107), Expect = 1e-04 Identities = 31/113 (27%), Positives = 51/113 (45%), Gaps = 20/113 (17%) Frame = +1 Query: 349 LRVATDNFDERNKLGEGGFGVVY----------KGILPDNEE---------IAVKRLSQS 471 L V+ DN E ++G G FG V + +P + +AVK+L Sbjct: 339 LNVSVDNIREVKQIGVGQFGAVVLAEMTGLSGSERCVPTKRDPSMLNGVALVAVKKLKPD 398 Query: 472 SRQGIEE-LKNELVLVAKLQHKNLVRLLGVCLEEQEKLLAYEYMPNKSLDTIL 627 + + + E+ V++LQH ++V+LL VC + + EYM N L+ L Sbjct: 399 VSEEVRQSFDKEIKFVSQLQHDSIVQLLAVCTHSKHPFIVMEYMENGDLNQFL 451
>CDK2_RAT (Q63699) Cell division protein kinase 2 (EC 2.7.11.22)| Length = 298 Score = 45.8 bits (107), Expect = 1e-04 Identities = 27/82 (32%), Positives = 47/82 (57%), Gaps = 3/82 (3%) Frame = +1 Query: 364 DNFDERNKLGEGGFGVVYKGILP-DNEEIAVKRLS-QSSRQGIEELK-NELVLVAKLQHK 534 +NF + K+GEG +GVVYK E +A+K++ + +G+ E+ L+ +L H Sbjct: 2 ENFQKVEKIGEGTYGVVYKAKNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHP 61 Query: 535 NLVRLLGVCLEEQEKLLAYEYM 600 N+V+LL V E + L +E++ Sbjct: 62 NIVKLLDVIHTENKLYLVFEFL 83
>CDK2_HUMAN (P24941) Cell division protein kinase 2 (EC 2.7.11.22) (p33 protein| kinase) Length = 298 Score = 45.8 bits (107), Expect = 1e-04 Identities = 27/82 (32%), Positives = 47/82 (57%), Gaps = 3/82 (3%) Frame = +1 Query: 364 DNFDERNKLGEGGFGVVYKGILP-DNEEIAVKRLS-QSSRQGIEELK-NELVLVAKLQHK 534 +NF + K+GEG +GVVYK E +A+K++ + +G+ E+ L+ +L H Sbjct: 2 ENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHP 61 Query: 535 NLVRLLGVCLEEQEKLLAYEYM 600 N+V+LL V E + L +E++ Sbjct: 62 NIVKLLDVIHTENKLYLVFEFL 83
>CDK2_CRIGR (O55076) Cell division protein kinase 2 (EC 2.7.11.22)| Length = 298 Score = 45.8 bits (107), Expect = 1e-04 Identities = 27/82 (32%), Positives = 47/82 (57%), Gaps = 3/82 (3%) Frame = +1 Query: 364 DNFDERNKLGEGGFGVVYKGILP-DNEEIAVKRLS-QSSRQGIEELK-NELVLVAKLQHK 534 +NF + K+GEG +GVVYK E +A+K++ + +G+ E+ L+ +L H Sbjct: 2 ENFQKVEKIGEGTYGVVYKAKNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHP 61 Query: 535 NLVRLLGVCLEEQEKLLAYEYM 600 N+V+LL V E + L +E++ Sbjct: 62 NIVKLLDVIHTENKLYLVFEFL 83
>CDK2_BOVIN (Q5E9Y0) Cell division protein kinase 2 (EC 2.7.11.22)| Length = 298 Score = 45.8 bits (107), Expect = 1e-04 Identities = 27/82 (32%), Positives = 47/82 (57%), Gaps = 3/82 (3%) Frame = +1 Query: 364 DNFDERNKLGEGGFGVVYKGILP-DNEEIAVKRLS-QSSRQGIEELK-NELVLVAKLQHK 534 +NF + K+GEG +GVVYK E +A+K++ + +G+ E+ L+ +L H Sbjct: 2 ENFQKVEKIGEGTYGVVYKAKNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHP 61 Query: 535 NLVRLLGVCLEEQEKLLAYEYM 600 N+V+LL V E + L +E++ Sbjct: 62 NIVKLLDVIHTENKLYLVFEFL 83
>ROS_AVISU (P00529) Tyrosine-protein kinase transforming protein ros (EC| 2.7.10.1) Length = 402 Score = 45.8 bits (107), Expect = 1e-04 Identities = 32/92 (34%), Positives = 45/92 (48%), Gaps = 8/92 (8%) Frame = +1 Query: 364 DNFDERNKLGEGGFGVVYKG----ILPDNE---EIAVKRLSQSSR-QGIEELKNELVLVA 519 D + LG G FG VY+G IL D +AVK L + + Q E E L++ Sbjct: 96 DKLNLHKLLGSGAFGEVYEGTALDILADGSGESRVAVKTLKRGATDQEKSEFLKEAHLMS 155 Query: 520 KLQHKNLVRLLGVCLEEQEKLLAYEYMPNKSL 615 K H ++++LLGVCL + + L E M L Sbjct: 156 KFDHPHILKLLGVCLLNEPQYLILELMEGGDL 187
>EPB1A_XENLA (Q91571) Ephrin type-B receptor 1-A precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor XEK) Length = 985 Score = 45.8 bits (107), Expect = 1e-04 Identities = 29/85 (34%), Positives = 46/85 (54%), Gaps = 5/85 (5%) Frame = +1 Query: 388 LGEGGFGVVYKGIL--PDNEEI--AVKRLSQS-SRQGIEELKNELVLVAKLQHKNLVRLL 552 +G G FG VYKG L P EI A+K L S + + +E ++ + H N++RL Sbjct: 626 IGAGEFGEVYKGRLKLPSKREISVAIKTLKAGYSEKQRRDFLSEASIMGQFDHPNIIRLE 685 Query: 553 GVCLEEQEKLLAYEYMPNKSLDTIL 627 GV + + ++ E+M N +LD+ L Sbjct: 686 GVVTKSRPVMIITEFMENGALDSFL 710
>CDK2_MOUSE (P97377) Cell division protein kinase 2 (EC 2.7.11.22)| Length = 346 Score = 45.8 bits (107), Expect = 1e-04 Identities = 27/82 (32%), Positives = 47/82 (57%), Gaps = 3/82 (3%) Frame = +1 Query: 364 DNFDERNKLGEGGFGVVYKGILP-DNEEIAVKRLS-QSSRQGIEELK-NELVLVAKLQHK 534 +NF + K+GEG +GVVYK E +A+K++ + +G+ E+ L+ +L H Sbjct: 2 ENFQKVEKIGEGTYGVVYKAKNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHP 61 Query: 535 NLVRLLGVCLEEQEKLLAYEYM 600 N+V+LL V E + L +E++ Sbjct: 62 NIVKLLDVIHTENKLYLVFEFL 83
>BTK_HUMAN (Q06187) Tyrosine-protein kinase BTK (EC 2.7.10.2) (Bruton's| tyrosine kinase) (Agammaglobulinaemia tyrosine kinase) (ATK) (B cell progenitor kinase) (BPK) Length = 658 Score = 45.8 bits (107), Expect = 1e-04 Identities = 26/77 (33%), Positives = 41/77 (53%) Frame = +1 Query: 385 KLGEGGFGVVYKGILPDNEEIAVKRLSQSSRQGIEELKNELVLVAKLQHKNLVRLLGVCL 564 +LG G FGVV G ++A+K + + S +E E ++ L H+ LV+L GVC Sbjct: 406 ELGTGQFGVVKYGKWRGQYDVAIKMIKEGSMSE-DEFIEEAKVMMNLSHEKLVQLYGVCT 464 Query: 565 EEQEKLLAYEYMPNKSL 615 +++ + EYM N L Sbjct: 465 KQRPIFIITEYMANGCL 481
>ROS_CHICK (P08941) Proto-oncogene tyrosine-protein kinase ROS precursor (EC| 2.7.10.1) (c-ros-1) Length = 2311 Score = 45.8 bits (107), Expect = 1e-04 Identities = 32/92 (34%), Positives = 45/92 (48%), Gaps = 8/92 (8%) Frame = +1 Query: 364 DNFDERNKLGEGGFGVVYKG----ILPDNE---EIAVKRLSQSSR-QGIEELKNELVLVA 519 D + LG G FG VY+G IL D +AVK L + + Q E E L++ Sbjct: 1959 DKLNLHKLLGSGAFGEVYEGTALDILADGSGESRVAVKTLKRGATDQEKSEFLKEAHLMS 2018 Query: 520 KLQHKNLVRLLGVCLEEQEKLLAYEYMPNKSL 615 K H ++++LLGVCL + + L E M L Sbjct: 2019 KFDHPHILKLLGVCLLNEPQYLILELMEGGDL 2050
>CDC2C_DROME (P23573) Cell division control protein 2 cognate (EC 2.7.11.22) (EC| 2.7.11.23) Length = 314 Score = 45.8 bits (107), Expect = 1e-04 Identities = 24/82 (29%), Positives = 45/82 (54%), Gaps = 3/82 (3%) Frame = +1 Query: 364 DNFDERNKLGEGGFGVVYKG-ILPDNEEIAVKRLS-QSSRQGIEELK-NELVLVAKLQHK 534 DNF K+GEG +G+VYK +++A+K++ + +G+ E+ L+ L+H Sbjct: 6 DNFQRAEKIGEGTYGIVYKARSNSTGQDVALKKIRLEGETEGVPSTAIREISLLKNLKHP 65 Query: 535 NLVRLLGVCLEEQEKLLAYEYM 600 N+V+L V + + +EY+ Sbjct: 66 NVVQLFDVVISGNNLYMIFEYL 87
>IGF1R_RAT (P24062) Insulin-like growth factor 1 receptor precursor (EC| 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain] Length = 1370 Score = 45.8 bits (107), Expect = 1e-04 Identities = 34/99 (34%), Positives = 54/99 (54%), Gaps = 8/99 (8%) Frame = +1 Query: 355 VATDNFDERNKLGEGGFGVVY----KGILPDNEE--IAVKRLSQ--SSRQGIEELKNELV 510 VA + +LG+G FG+VY KG++ D E +A+K +++ S R+ IE L NE Sbjct: 995 VAREKITMNRELGQGSFGMVYEGVAKGVVKDEPETRVAIKTVNEAASMRERIEFL-NEAS 1053 Query: 511 LVAKLQHKNLVRLLGVCLEEQEKLLAYEYMPNKSLDTIL 627 ++ + ++VRLLGV + Q L+ E M L + L Sbjct: 1054 VMKEFNCHHVVRLLGVVSQGQPTLVIMELMTRGDLKSYL 1092
>EPB1B_XENLA (Q91736) Ephrin type-B receptor 1-B (EC 2.7.10.1) (Tyrosine-protein| kinase receptor XELK) (Fragment) Length = 902 Score = 45.8 bits (107), Expect = 1e-04 Identities = 29/85 (34%), Positives = 46/85 (54%), Gaps = 5/85 (5%) Frame = +1 Query: 388 LGEGGFGVVYKGIL--PDNEEI--AVKRLSQS-SRQGIEELKNELVLVAKLQHKNLVRLL 552 +G G FG VYKG L P EI A+K L S + + +E ++ + H N++RL Sbjct: 543 IGAGEFGEVYKGRLKLPSKREISVAIKTLKAGYSEKQRRDFLSEASIMGQFDHPNIIRLE 602 Query: 553 GVCLEEQEKLLAYEYMPNKSLDTIL 627 GV + + ++ E+M N +LD+ L Sbjct: 603 GVVTKSRPVMIITEFMENGALDSFL 627
>MERTK_RAT (P57097) Proto-oncogene tyrosine-protein kinase MER precursor (EC| 2.7.10.1) (C-mer) (Receptor tyrosine kinase MerTK) Length = 994 Score = 45.8 bits (107), Expect = 1e-04 Identities = 27/66 (40%), Positives = 39/66 (59%), Gaps = 6/66 (9%) Frame = +1 Query: 388 LGEGGFGVVYKGILPD----NEEIAVK--RLSQSSRQGIEELKNELVLVAKLQHKNLVRL 549 LGEG FG V +G L ++++AVK +L S + IEE +E + H N++RL Sbjct: 588 LGEGEFGSVMEGNLKQEDGTSQKVAVKTMKLDNFSLREIEEFLSEAACMKDFNHPNVIRL 647 Query: 550 LGVCLE 567 LGVC+E Sbjct: 648 LGVCIE 653
>AURKB_MOUSE (O70126) Serine/threonine-protein kinase 12 (EC 2.7.11.1)| (Aurora-related kinase 2) (Serine/threonine-protein kinase 5) (STK-1) (Aurora-B) Length = 345 Score = 45.4 bits (106), Expect = 1e-04 Identities = 28/88 (31%), Positives = 46/88 (52%), Gaps = 4/88 (4%) Frame = +1 Query: 364 DNFDERNKLGEGGFGVVYKGILPDNEEIAVKRL---SQSSRQGIE-ELKNELVLVAKLQH 531 DNF+ LG+G FG VY + I ++ SQ ++G+E +L+ E+ + A L+H Sbjct: 80 DNFEIGRPLGKGKFGNVYLAREKKSRFIVALKILFKSQIEKEGVEHQLRREIEIQAHLKH 139 Query: 532 KNLVRLLGVCLEEQEKLLAYEYMPNKSL 615 N+++L ++Q L EY P L Sbjct: 140 PNILQLYNYFYDQQRIYLILEYAPRGEL 167
>ALK_MOUSE (P97793) ALK tyrosine kinase receptor precursor (EC 2.7.10.1)| (Anaplastic lymphoma kinase) (CD246 antigen) Length = 1621 Score = 45.4 bits (106), Expect = 1e-04 Identities = 28/87 (32%), Positives = 45/87 (51%), Gaps = 7/87 (8%) Frame = +1 Query: 388 LGEGGFGVVYKGIL------PDNEEIAVKRLSQ-SSRQGIEELKNELVLVAKLQHKNLVR 546 LG G FG VY+G + P ++AVK L + S Q + E ++++K H+N+VR Sbjct: 1126 LGHGAFGEVYEGQVSGMPNDPSPLQVAVKTLPEVCSEQDELDFLMEALIISKFNHQNIVR 1185 Query: 547 LLGVCLEEQEKLLAYEYMPNKSLDTIL 627 +GV L+ + + E M L + L Sbjct: 1186 CIGVSLQALPRFILLELMAGGDLKSFL 1212
>INSR_XENLA (Q9PVZ4) Insulin receptor precursor (EC 2.7.10.1) (IR) (Xe-InsR)| (XTK-1b) [Contains: Insulin receptor alpha subunit; Insulin receptor beta subunit] Length = 1362 Score = 45.4 bits (106), Expect = 1e-04 Identities = 34/99 (34%), Positives = 53/99 (53%), Gaps = 8/99 (8%) Frame = +1 Query: 355 VATDNFDERNKLGEGGFGVVYKGILPD------NEEIAVKRLSQSS--RQGIEELKNELV 510 V D + +LG+G FG+VY+GI D +AVK +++S+ R+ IE L NE Sbjct: 1007 VPRDKINLLRELGQGSFGMVYEGIAKDIIKGEPEVRVAVKTVNESASLRERIEFL-NEAS 1065 Query: 511 LVAKLQHKNLVRLLGVCLEEQEKLLAYEYMPNKSLDTIL 627 ++ ++VRLLGV + Q L+ E M + L + L Sbjct: 1066 VMKAFNCHHVVRLLGVVSKGQPTLVIMELMAHGDLKSYL 1104
>IGF1R_BOVIN (Q05688) Insulin-like growth factor 1 receptor precursor (EC| 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain] (F Length = 640 Score = 45.4 bits (106), Expect = 1e-04 Identities = 34/99 (34%), Positives = 54/99 (54%), Gaps = 8/99 (8%) Frame = +1 Query: 355 VATDNFDERNKLGEGGFGVVY----KGILPDNEE--IAVKRLSQ--SSRQGIEELKNELV 510 VA + +LG+G FG+VY KG++ D E +A+K +++ S R+ IE L NE Sbjct: 267 VAREKITMSRELGQGSFGMVYEGVAKGVVKDEPETRVAIKTVNEAASMRERIEFL-NEAS 325 Query: 511 LVAKLQHKNLVRLLGVCLEEQEKLLAYEYMPNKSLDTIL 627 ++ + ++VRLLGV + Q L+ E M L + L Sbjct: 326 VMKEFNCHHVVRLLGVVSQGQPTLVIMELMTRGDLKSYL 364
>CDC2_CHICK (P13863) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1) Length = 303 Score = 45.4 bits (106), Expect = 1e-04 Identities = 29/93 (31%), Positives = 53/93 (56%), Gaps = 6/93 (6%) Frame = +1 Query: 364 DNFDERNKLGEGGFGVVYKG-ILPDNEEIAVKRLS-QSSRQGIEELK-NELVLVAKLQHK 534 +++ + K+GEG +GVVYKG + +A+K++ +S +G+ E+ L+ +L H Sbjct: 2 EDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELHHP 61 Query: 535 NLVRLLGVCLEEQEKLLAYEYMP---NKSLDTI 624 N+V L V +++ L +E++ K LDTI Sbjct: 62 NIVCLQDVLMQDARLYLIFEFLSMDLKKYLDTI 94
>EPHB1_RAT (P09759) Ephrin type-B receptor 1 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EPH-2) (ELK) Length = 984 Score = 45.4 bits (106), Expect = 1e-04 Identities = 29/85 (34%), Positives = 46/85 (54%), Gaps = 5/85 (5%) Frame = +1 Query: 388 LGEGGFGVVYKGIL--PDNEEI--AVKRLSQS-SRQGIEELKNELVLVAKLQHKNLVRLL 552 +G G FG VYKG L P EI A+K L S + + +E ++ + H N++RL Sbjct: 625 IGAGEFGEVYKGRLKLPGKREIYVAIKTLKAGYSEKQRRDFLSEASIMGQFDHPNIIRLE 684 Query: 553 GVCLEEQEKLLAYEYMPNKSLDTIL 627 GV + + ++ E+M N +LD+ L Sbjct: 685 GVVTKSRPVMIITEFMENGALDSFL 709
>EPHB1_HUMAN (P54762) Ephrin type-B receptor 1 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EPH-2) (NET) (HEK6) (ELK) Length = 984 Score = 45.4 bits (106), Expect = 1e-04 Identities = 29/85 (34%), Positives = 46/85 (54%), Gaps = 5/85 (5%) Frame = +1 Query: 388 LGEGGFGVVYKGIL--PDNEEI--AVKRLSQS-SRQGIEELKNELVLVAKLQHKNLVRLL 552 +G G FG VYKG L P EI A+K L S + + +E ++ + H N++RL Sbjct: 625 IGAGEFGEVYKGRLKLPGKREIYVAIKTLKAGYSEKQRRDFLSEASIMGQFDHPNIIRLE 684 Query: 553 GVCLEEQEKLLAYEYMPNKSLDTIL 627 GV + + ++ E+M N +LD+ L Sbjct: 685 GVVTKSRPVMIITEFMENGALDSFL 709
>EPHB1_CHICK (Q07494) Ephrin type-B receptor 1 (EC 2.7.10.1) (Tyrosine-protein| kinase receptor EPH-2) (Tyrosine kinase CEK6 receptor) (Fragment) Length = 984 Score = 45.4 bits (106), Expect = 1e-04 Identities = 29/85 (34%), Positives = 46/85 (54%), Gaps = 5/85 (5%) Frame = +1 Query: 388 LGEGGFGVVYKGIL--PDNEEI--AVKRLSQS-SRQGIEELKNELVLVAKLQHKNLVRLL 552 +G G FG VYKG L P EI A+K L S + + +E ++ + H N++RL Sbjct: 625 IGAGEFGEVYKGRLKLPGKREIYVAIKTLKAGYSEKQRRDFLSEASIMGQFDHPNIIRLE 684 Query: 553 GVCLEEQEKLLAYEYMPNKSLDTIL 627 GV + + ++ E+M N +LD+ L Sbjct: 685 GVVTKSRPVMIITEFMENGALDSFL 709
>CDC21_ORYSA (P29618) Cell division control protein 2 homolog 1 (EC 2.7.11.22)| Length = 294 Score = 45.4 bits (106), Expect = 1e-04 Identities = 28/82 (34%), Positives = 44/82 (53%), Gaps = 3/82 (3%) Frame = +1 Query: 364 DNFDERNKLGEGGFGVVYKGI-LPDNEEIAVK--RLSQSSRQGIEELKNELVLVAKLQHK 534 + +++ K+GEG +GVVY+ NE IA+K RL Q E+ L+ ++ H Sbjct: 2 EQYEKEEKIGEGTYGVVYRARDKVTNETIALKKIRLEQEDEGVPSTAIREISLLKEMHHG 61 Query: 535 NLVRLLGVCLEEQEKLLAYEYM 600 N+VRL V E+ L +EY+ Sbjct: 62 NIVRLHDVIHSEKRIYLVFEYL 83
>ERBB_AVIEU (P11273) Tyrosine-protein kinase transforming protein erbB (EC| 2.7.10.1) Length = 540 Score = 45.4 bits (106), Expect = 1e-04 Identities = 28/84 (33%), Positives = 51/84 (60%), Gaps = 6/84 (7%) Frame = +1 Query: 370 FDERNKLGEGGFGVVYKGI-LPDNEEI----AVKRLSQS-SRQGIEELKNELVLVAKLQH 531 F + LG G FG VYKG+ +P+ E++ A+K L ++ S + +E+ +E ++A + + Sbjct: 132 FKKVKVLGFGAFGTVYKGLWIPEGEKVTIPVAIKELREATSPKANKEILDEAYVMASVDN 191 Query: 532 KNLVRLLGVCLEEQEKLLAYEYMP 603 ++ RLLG+CL +L+ + MP Sbjct: 192 PHVCRLLGICLTSTVQLIT-QLMP 214
>M3K10_HUMAN (Q02779) Mitogen-activated protein kinase kinase kinase 10 (EC| 2.7.11.25) (Mixed lineage kinase 2) (Protein kinase MST) Length = 954 Score = 45.4 bits (106), Expect = 1e-04 Identities = 30/84 (35%), Positives = 41/84 (48%), Gaps = 4/84 (4%) Frame = +1 Query: 388 LGEGGFGVVYKGILPDNEEIAVK--RLSQSSRQGI--EELKNELVLVAKLQHKNLVRLLG 555 +G GGFG VY+ + EE+AVK RL + E++ E L LQH N++ L G Sbjct: 104 IGVGGFGKVYRALWR-GEEVAVKAARLDPEKDPAVTAEQVCQEARLFGALQHPNIIALRG 162 Query: 556 VCLEEQEKLLAYEYMPNKSLDTIL 627 CL L EY +L +L Sbjct: 163 ACLNPPHLCLVMEYARGGALSRVL 186
>BTK_MOUSE (P35991) Tyrosine-protein kinase BTK (EC 2.7.10.2) (Bruton's| tyrosine kinase) (Agammaglobulinaemia tyrosine kinase) (ATK) (B cell progenitor kinase) (BPK) (Kinase EMB) Length = 658 Score = 45.4 bits (106), Expect = 1e-04 Identities = 26/77 (33%), Positives = 41/77 (53%) Frame = +1 Query: 385 KLGEGGFGVVYKGILPDNEEIAVKRLSQSSRQGIEELKNELVLVAKLQHKNLVRLLGVCL 564 +LG G FGVV G ++A+K + + S +E E ++ L H+ LV+L GVC Sbjct: 406 ELGTGQFGVVKYGKWRGQYDVAIKMIREGSMSE-DEFIEEAKVMMNLSHEKLVQLYGVCT 464 Query: 565 EEQEKLLAYEYMPNKSL 615 +++ + EYM N L Sbjct: 465 KQRPIFIITEYMANGCL 481
>CDC2_HUMAN (P06493) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1) Length = 297 Score = 45.4 bits (106), Expect = 1e-04 Identities = 28/93 (30%), Positives = 54/93 (58%), Gaps = 6/93 (6%) Frame = +1 Query: 364 DNFDERNKLGEGGFGVVYKG-ILPDNEEIAVKRLS-QSSRQGIEELK-NELVLVAKLQHK 534 +++ + K+GEG +GVVYKG + +A+K++ +S +G+ E+ L+ +L+H Sbjct: 2 EDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRHP 61 Query: 535 NLVRLLGVCLEEQEKLLAYEYMP---NKSLDTI 624 N+V L V +++ L +E++ K LD+I Sbjct: 62 NIVSLQDVLMQDSRLYLIFEFLSMDLKKYLDSI 94
>CDC2_BOVIN (P48734) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1) Length = 297 Score = 45.4 bits (106), Expect = 1e-04 Identities = 28/93 (30%), Positives = 54/93 (58%), Gaps = 6/93 (6%) Frame = +1 Query: 364 DNFDERNKLGEGGFGVVYKG-ILPDNEEIAVKRLS-QSSRQGIEELK-NELVLVAKLQHK 534 +++ + K+GEG +GVVYKG + +A+K++ +S +G+ E+ L+ +L+H Sbjct: 2 EDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRHP 61 Query: 535 NLVRLLGVCLEEQEKLLAYEYMP---NKSLDTI 624 N+V L V +++ L +E++ K LD+I Sbjct: 62 NIVSLQDVLMQDSRLYLIFEFLSMDLKKYLDSI 94
>AURKB_RAT (O55099) Serine/threonine-protein kinase 12 (EC 2.7.11.1) (Aurora-| and Ipl1-like midbody-associated protein 1) (AIM-1) (Aurora-B) Length = 343 Score = 45.4 bits (106), Expect = 1e-04 Identities = 28/88 (31%), Positives = 46/88 (52%), Gaps = 4/88 (4%) Frame = +1 Query: 364 DNFDERNKLGEGGFGVVYKGILPDNEEIAVKRL---SQSSRQGIE-ELKNELVLVAKLQH 531 DNF+ LG+G FG VY + I ++ SQ ++G+E +L+ E+ + A L+H Sbjct: 78 DNFEIGRPLGKGKFGNVYLAREKKSRFIVALKILFKSQIEKEGVEHQLRREIEIQAHLKH 137 Query: 532 KNLVRLLGVCLEEQEKLLAYEYMPNKSL 615 N+++L ++Q L EY P L Sbjct: 138 PNILQLYNYFYDQQRIYLILEYAPRGEL 165
>CDC2H_PLAYO (Q7RM49) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) Length = 289 Score = 45.4 bits (106), Expect = 1e-04 Identities = 24/75 (32%), Positives = 45/75 (60%), Gaps = 3/75 (4%) Frame = +1 Query: 385 KLGEGGFGVVYKGILPDNEEIAVKRLS-QSSRQGIEELKN--ELVLVAKLQHKNLVRLLG 555 K+GEG +GVVYK D E A+K++ + +GI + E+ ++ +L+H N+V+L Sbjct: 9 KIGEGTYGVVYKAQNSDGESFALKKIRLEKEDEGIPSTVSIREISILKELRHSNIVKLYD 68 Query: 556 VCLEEQEKLLAYEYM 600 V ++ +L +E++ Sbjct: 69 VIHAKKRLILVFEHL 83
>UFO_HUMAN (P30530) Tyrosine-protein kinase receptor UFO precursor (EC| 2.7.10.1) (AXL oncogene) Length = 887 Score = 45.4 bits (106), Expect = 1e-04 Identities = 25/69 (36%), Positives = 42/69 (60%), Gaps = 5/69 (7%) Frame = +1 Query: 388 LGEGGFGVVYKGILPDNEEI---AVK--RLSQSSRQGIEELKNELVLVAKLQHKNLVRLL 552 LGEG FG V +G L ++ I AVK +++ +R +E+ +E V + + H N++RL+ Sbjct: 535 LGEGEFGAVMEGQLNQDDSILKVAVKTMKIAICTRSELEDFLSEAVCMKEFDHPNVMRLI 594 Query: 553 GVCLEEQEK 579 GVC + E+ Sbjct: 595 GVCFQGSER 603
>IGF1R_HUMAN (P08069) Insulin-like growth factor 1 receptor precursor (EC| 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD221 antigen) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 recepto Length = 1367 Score = 45.4 bits (106), Expect = 1e-04 Identities = 34/99 (34%), Positives = 54/99 (54%), Gaps = 8/99 (8%) Frame = +1 Query: 355 VATDNFDERNKLGEGGFGVVY----KGILPDNEE--IAVKRLSQ--SSRQGIEELKNELV 510 VA + +LG+G FG+VY KG++ D E +A+K +++ S R+ IE L NE Sbjct: 994 VAREKITMSRELGQGSFGMVYEGVAKGVVKDEPETRVAIKTVNEAASMRERIEFL-NEAS 1052 Query: 511 LVAKLQHKNLVRLLGVCLEEQEKLLAYEYMPNKSLDTIL 627 ++ + ++VRLLGV + Q L+ E M L + L Sbjct: 1053 VMKEFNCHHVVRLLGVVSQGQPTLVIMELMTRGDLKSYL 1091
>PTK7_HUMAN (Q13308) Tyrosine-protein kinase-like 7 precursor (Colon carcinoma| kinase 4) (CCK-4) Length = 1070 Score = 45.1 bits (105), Expect = 2e-04 Identities = 28/86 (32%), Positives = 40/86 (46%), Gaps = 6/86 (6%) Frame = +1 Query: 388 LGEGGFGVVYKGILPDNEE------IAVKRLSQSSRQGIEELKNELVLVAKLQHKNLVRL 549 LG+ FG V+ EE + VK L Q + + EL + KL H N+VRL Sbjct: 802 LGKSEFGEVFLAKAQGLEEGVAETLVLVKSLQSKDEQQQLDFRRELEMFGKLNHANVVRL 861 Query: 550 LGVCLEEQEKLLAYEYMPNKSLDTIL 627 LG+C E + + EY+ + L L Sbjct: 862 LGLCREAEPHYMVLEYVDLEDLKQFL 887
>PHO85_ASHGO (Q751E8) Negative regulator of the PHO system (EC 2.7.11.22)| (Serine/threonine-protein kinase PHO85) Length = 303 Score = 45.1 bits (105), Expect = 2e-04 Identities = 26/81 (32%), Positives = 43/81 (53%), Gaps = 2/81 (2%) Frame = +1 Query: 370 FDERNKLGEGGFGVVYKGILPDNE-EIAVKRLSQSSRQGIEELK-NELVLVAKLQHKNLV 543 F + +LG G + VYKG+ +A+K + S +G E+ L+ +L+H+N+V Sbjct: 9 FKQLERLGNGTYATVYKGLNKTTGLYVALKEVKLDSEEGTPSTAIREISLMKELKHENIV 68 Query: 544 RLLGVCLEEQEKLLAYEYMPN 606 RL V E + L +E+M N Sbjct: 69 RLYDVIHTENKLTLVFEFMDN 89
>BMX_HUMAN (P51813) Cytoplasmic tyrosine-protein kinase BMX (EC 2.7.10.2)| (Bone marrow tyrosine kinase gene in chromosome X protein) (Epithelial and endothelial tyrosine kinase) (ETK) (NTK38) Length = 675 Score = 45.1 bits (105), Expect = 2e-04 Identities = 27/77 (35%), Positives = 38/77 (49%) Frame = +1 Query: 385 KLGEGGFGVVYKGILPDNEEIAVKRLSQSSRQGIEELKNELVLVAKLQHKNLVRLLGVCL 564 +LG G FGVV G ++AVK + + S +E E + KL H LV+ GVC Sbjct: 422 ELGSGQFGVVQLGKWKGQYDVAVKMIKEGSMSE-DEFFQEAQTMMKLSHPKLVKFYGVCS 480 Query: 565 EEQEKLLAYEYMPNKSL 615 +E + EY+ N L Sbjct: 481 KEYPIYIVTEYISNGCL 497
>BTK_CHICK (Q8JH64) Tyrosine-protein kinase BTK (EC 2.7.10.2) (Bruton's| tyrosine kinase) Length = 657 Score = 45.1 bits (105), Expect = 2e-04 Identities = 26/77 (33%), Positives = 41/77 (53%) Frame = +1 Query: 385 KLGEGGFGVVYKGILPDNEEIAVKRLSQSSRQGIEELKNELVLVAKLQHKNLVRLLGVCL 564 +LG G FGVV G +A+K + + S +E +E ++ L H+ LV+L GVC Sbjct: 405 ELGTGQFGVVKYGKWRGQYNVAIKMIREGSMSE-DEFIDEAKVMMNLSHEKLVQLYGVCT 463 Query: 565 EEQEKLLAYEYMPNKSL 615 +++ + EYM N L Sbjct: 464 KQRPIFIITEYMANGCL 480
>CDK3_HUMAN (Q00526) Cell division protein kinase 3 (EC 2.7.11.22)| Length = 305 Score = 45.1 bits (105), Expect = 2e-04 Identities = 27/82 (32%), Positives = 48/82 (58%), Gaps = 3/82 (3%) Frame = +1 Query: 364 DNFDERNKLGEGGFGVVYKGILPDNEE-IAVKRLSQS-SRQGIEELK-NELVLVAKLQHK 534 D F + K+GEG +GVVYK + + +A+K++ +G+ E+ L+ +L+H Sbjct: 2 DMFQKVEKIGEGTYGVVYKAKNRETGQLVALKKIRLDLEMEGVPSTAIREISLLKELKHP 61 Query: 535 NLVRLLGVCLEEQEKLLAYEYM 600 N+VRLL V E++ L +E++ Sbjct: 62 NIVRLLDVVHNERKLYLVFEFL 83
>LCK_HUMAN (P06239) Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2)| (p56-LCK) (Lymphocyte cell-specific protein-tyrosine kinase) (LSK) (T cell-specific protein-tyrosine kinase) Length = 508 Score = 45.1 bits (105), Expect = 2e-04 Identities = 30/77 (38%), Positives = 42/77 (54%) Frame = +1 Query: 385 KLGEGGFGVVYKGILPDNEEIAVKRLSQSSRQGIEELKNELVLVAKLQHKNLVRLLGVCL 564 +LG G FG V+ G + ++AVK L Q S + E L+ +LQH+ LVRL V Sbjct: 249 RLGAGQFGEVWMGYYNGHTKVAVKSLKQGS-MSPDAFLAEANLMKQLQHQRLVRLYAVVT 307 Query: 565 EEQEKLLAYEYMPNKSL 615 +E ++ EYM N SL Sbjct: 308 QEPIYIIT-EYMENGSL 323
>LYN_MOUSE (P25911) Tyrosine-protein kinase Lyn (EC 2.7.10.2)| Length = 511 Score = 44.7 bits (104), Expect = 2e-04 Identities = 27/77 (35%), Positives = 40/77 (51%) Frame = +1 Query: 385 KLGEGGFGVVYKGILPDNEEIAVKRLSQSSRQGIEELKNELVLVAKLQHKNLVRLLGVCL 564 KLG G FG V+ G ++ ++AVK L + ++ E L+ LQH LVRL V Sbjct: 251 KLGAGQFGEVWMGYYNNSTKVAVKTLKPGT-MSVQAFLEEANLMKTLQHDKLVRLYAVVT 309 Query: 565 EEQEKLLAYEYMPNKSL 615 +E+ + E+M SL Sbjct: 310 KEEPIYIITEFMAKGSL 326
>LYN_HUMAN (P07948) Tyrosine-protein kinase Lyn (EC 2.7.10.2)| Length = 511 Score = 44.7 bits (104), Expect = 2e-04 Identities = 27/77 (35%), Positives = 39/77 (50%) Frame = +1 Query: 385 KLGEGGFGVVYKGILPDNEEIAVKRLSQSSRQGIEELKNELVLVAKLQHKNLVRLLGVCL 564 +LG G FG V+ G ++ ++AVK L + ++ E L+ LQH LVRL V Sbjct: 251 RLGAGQFGEVWMGYYNNSTKVAVKTLKPGT-MSVQAFLEEANLMKTLQHDKLVRLYAVVT 309 Query: 565 EEQEKLLAYEYMPNKSL 615 E+ + EYM SL Sbjct: 310 REEPIYIITEYMAKGSL 326
>PR2_DROME (Q9I7F7) Tyrosine-protein kinase PR2 (EC 2.7.10.2)| Length = 1337 Score = 44.7 bits (104), Expect = 2e-04 Identities = 29/97 (29%), Positives = 47/97 (48%), Gaps = 4/97 (4%) Frame = +1 Query: 355 VATDNFDERNKLGEGGFGVVYKGILPDNEE---IAVKRLSQSSRQGIE-ELKNELVLVAK 522 + D+ +LG G FG+V +G+ + E +A+K L + Q E E ++ Sbjct: 128 IPADSISVNKQLGTGEFGIVQQGVWSNGNERIQVAIKCLCRERMQSNPMEFLKEAAIMHS 187 Query: 523 LQHKNLVRLLGVCLEEQEKLLAYEYMPNKSLDTILFD 633 ++H+N+VRL GV L +L E +SL L D Sbjct: 188 IEHENIVRLYGVVLATDSLMLVTELAHLRSLLECLKD 224
>MET_PIG (Q2QLE0) Hepatocyte growth factor receptor precursor (EC 2.7.10.1)| (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met) Length = 1381 Score = 44.7 bits (104), Expect = 2e-04 Identities = 28/82 (34%), Positives = 44/82 (53%), Gaps = 6/82 (7%) Frame = +1 Query: 388 LGEGGFGVVYKGILPDNEE----IAVKRLSQSSRQG-IEELKNELVLVAKLQHKNLVRLL 552 +G G FG VY G L DN++ AVK L++ + G + + E +++ H N++ LL Sbjct: 1084 IGRGHFGCVYHGTLLDNDDKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNVLSLL 1143 Query: 553 GVCL-EEQEKLLAYEYMPNKSL 615 G+CL E L+ YM + L Sbjct: 1144 GICLRSEGSPLVVLPYMKHGDL 1165
>MET_HORSE (Q2QLA9) Hepatocyte growth factor receptor precursor (EC 2.7.10.1)| (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met) Length = 1381 Score = 44.7 bits (104), Expect = 2e-04 Identities = 28/82 (34%), Positives = 44/82 (53%), Gaps = 6/82 (7%) Frame = +1 Query: 388 LGEGGFGVVYKGILPDNEE----IAVKRLSQSSRQG-IEELKNELVLVAKLQHKNLVRLL 552 +G G FG VY G L DN++ AVK L++ + G + + E +++ H N++ LL Sbjct: 1084 IGRGHFGCVYHGTLLDNDDKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNVLSLL 1143 Query: 553 GVCL-EEQEKLLAYEYMPNKSL 615 G+CL E L+ YM + L Sbjct: 1144 GICLRSEGSPLVVLPYMKHGDL 1165
>JAK1_HUMAN (P23458) Tyrosine-protein kinase JAK1 (EC 2.7.10.2) (Janus kinase 1)| (JAK-1) Length = 1142 Score = 44.7 bits (104), Expect = 2e-04 Identities = 31/87 (35%), Positives = 46/87 (52%), Gaps = 7/87 (8%) Frame = +1 Query: 388 LGEGGFGVV----YKGILPDNEEIAVKRLS-QSSRQGIEELKNELVLVAKLQHKNLVRLL 552 LGEG FG V Y E++AVK L +S I +LK E+ ++ L H+N+V+ Sbjct: 870 LGEGHFGKVELCRYDPEDNTGEQVAVKSLKPESGGNHIADLKKEIEILRNLYHENIVKYK 929 Query: 553 GVCLEEQEK--LLAYEYMPNKSLDTIL 627 G+C E+ L E++P+ SL L Sbjct: 930 GICTEDGGNGIKLIMEFLPSGSLKEYL 956 Score = 34.3 bits (77), Expect = 0.32 Identities = 23/103 (22%), Positives = 44/103 (42%), Gaps = 11/103 (10%) Frame = +1 Query: 352 RVATDNFDERNKLGEGGFGVVYKGILPDNEE-----------IAVKRLSQSSRQGIEELK 498 R+ + + LG G +Y G L D ++ + +K L S R Sbjct: 565 RILKKDLVQGEHLGRGTRTHIYSGTLMDYKDDEGTSEEKKIKVILKVLDPSHRDISLAFF 624 Query: 499 NELVLVAKLQHKNLVRLLGVCLEEQEKLLAYEYMPNKSLDTIL 627 ++ ++ HK++V L GVC+ + E ++ E++ LD + Sbjct: 625 EAASMMRQVSHKHIVYLYGVCVRDVENIMVEEFVEGGPLDLFM 667
>MET_CANFA (Q75ZY9) Hepatocyte growth factor receptor precursor (EC 2.7.10.1)| (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met) Length = 1382 Score = 44.7 bits (104), Expect = 2e-04 Identities = 28/82 (34%), Positives = 44/82 (53%), Gaps = 6/82 (7%) Frame = +1 Query: 388 LGEGGFGVVYKGILPDNEE----IAVKRLSQSSRQG-IEELKNELVLVAKLQHKNLVRLL 552 +G G FG VY G L DN++ AVK L++ + G + + E +++ H N++ LL Sbjct: 1085 IGRGHFGCVYHGTLLDNDDKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNVLSLL 1144 Query: 553 GVCL-EEQEKLLAYEYMPNKSL 615 G+CL E L+ YM + L Sbjct: 1145 GICLRSEGSPLVVLPYMKHGDL 1166
>TAOK2_RAT (Q9JLS3) Serine/threonine-protein kinase TAO2 (EC 2.7.11.1)| (Thousand and one amino acid protein 2) Length = 1235 Score = 44.3 bits (103), Expect = 3e-04 Identities = 26/89 (29%), Positives = 46/89 (51%), Gaps = 4/89 (4%) Frame = +1 Query: 370 FDERNKLGEGGFGVVY-KGILPDNEEIAVKRLSQSSRQGIE---ELKNELVLVAKLQHKN 537 F + ++G G FG VY + ++E +A+K++S S +Q E ++ E+ + KL+H N Sbjct: 28 FSDLREIGHGSFGAVYFARDVRNSEVVAIKKMSYSGKQSNEKWQDIIKEVRFLQKLRHPN 87 Query: 538 LVRLLGVCLEEQEKLLAYEYMPNKSLDTI 624 ++ G L E L EY + D + Sbjct: 88 TIQYRGCYLREHTAWLVMEYCLGSASDLL 116
>TAOK2_HUMAN (Q9UL54) Serine/threonine-protein kinase TAO2 (EC 2.7.11.1)| (Thousand and one amino acid protein 2) (Prostate-derived STE20-like kinase 1) (PSK-1) (Kinase from chicken homolog C) (hKFC-C) Length = 1235 Score = 44.3 bits (103), Expect = 3e-04 Identities = 26/89 (29%), Positives = 46/89 (51%), Gaps = 4/89 (4%) Frame = +1 Query: 370 FDERNKLGEGGFGVVY-KGILPDNEEIAVKRLSQSSRQGIE---ELKNELVLVAKLQHKN 537 F + ++G G FG VY + ++E +A+K++S S +Q E ++ E+ + KL+H N Sbjct: 28 FSDLREIGHGSFGAVYFARDVRNSEVVAIKKMSYSGKQSNEKWQDIIKEVRFLQKLRHPN 87 Query: 538 LVRLLGVCLEEQEKLLAYEYMPNKSLDTI 624 ++ G L E L EY + D + Sbjct: 88 TIQYRGCYLREHTAWLVMEYCLGSASDLL 116
>UFO_MOUSE (Q00993) Tyrosine-protein kinase receptor UFO precursor (EC| 2.7.10.1) (Adhesion-related kinase) Length = 888 Score = 44.3 bits (103), Expect = 3e-04 Identities = 24/69 (34%), Positives = 42/69 (60%), Gaps = 5/69 (7%) Frame = +1 Query: 388 LGEGGFGVVYKGILPDNEEI---AVK--RLSQSSRQGIEELKNELVLVAKLQHKNLVRLL 552 LGEG FG V +G L ++ I AVK +++ +R +E+ +E V + + H N++RL+ Sbjct: 536 LGEGEFGAVMEGQLNQDDSILKVAVKTMKIAICTRSELEDFLSEAVCMKEFDHPNVMRLI 595 Query: 553 GVCLEEQEK 579 GVC + ++ Sbjct: 596 GVCFQGSDR 604
>M3K7_DROME (Q9V3Q6) Mitogen-activated protein kinase kinase kinase 7 (EC| 2.7.11.25) (TGF-beta-activated kinase 1) (dTAK1) Length = 678 Score = 44.3 bits (103), Expect = 3e-04 Identities = 29/96 (30%), Positives = 52/96 (54%), Gaps = 3/96 (3%) Frame = +1 Query: 349 LRVATDNFDE---RNKLGEGGFGVVYKGILPDNEEIAVKRLSQSSRQGIEELKNELVLVA 519 L+ A +F E R K+G G +GVV K + D + +AVK S+ Q ++++ E+ ++ Sbjct: 9 LQAAYVDFSEITLREKVGHGSYGVVCKAVWRD-KLVAVKEFFASAEQ--KDIEKEVKQLS 65 Query: 520 KLQHKNLVRLLGVCLEEQEKLLAYEYMPNKSLDTIL 627 +++H N++ L G+ +Q L E+ SL L Sbjct: 66 RVKHPNIIALHGISSYQQATYLIMEFAEGGSLHNFL 101
>JAK1_MOUSE (P52332) Tyrosine-protein kinase JAK1 (EC 2.7.10.2) (Janus kinase 1)| (JAK-1) Length = 1153 Score = 44.3 bits (103), Expect = 3e-04 Identities = 36/107 (33%), Positives = 55/107 (51%), Gaps = 13/107 (12%) Frame = +1 Query: 346 TLRVATDNFDER-----NKLGEGGFGVVYKGILP---DN--EEIAVKRLS-QSSRQGIEE 492 T V +F++R LGEG FG V DN E++AVK L +S I + Sbjct: 861 TTEVDPTHFEKRFLKRIRDLGEGHFGKVELCRYDPEGDNTGEQVAVKSLKPESGGNHIAD 920 Query: 493 LKNELVLVAKLQHKNLVRLLGVCLEEQEK--LLAYEYMPNKSLDTIL 627 LK E+ ++ L H+N+V+ G+C+E+ L E++P+ SL L Sbjct: 921 LKKEIEILRNLYHENIVKYKGICMEDGGNGIKLIMEFLPSGSLKEYL 967 Score = 33.9 bits (76), Expect = 0.42 Identities = 23/103 (22%), Positives = 44/103 (42%), Gaps = 11/103 (10%) Frame = +1 Query: 352 RVATDNFDERNKLGEGGFGVVYKGILPDNEE-----------IAVKRLSQSSRQGIEELK 498 R+ + + LG G +Y G L D ++ + +K L S R Sbjct: 576 RILKKDIIQGEHLGRGTRTHIYSGTLLDYKDEEGIAEEKKIKVILKVLDPSHRDISLAFF 635 Query: 499 NELVLVAKLQHKNLVRLLGVCLEEQEKLLAYEYMPNKSLDTIL 627 ++ ++ HK++V L GVC+ + E ++ E++ LD + Sbjct: 636 EAASMMRQVSHKHIVYLYGVCVRDVENIMVEEFVEGGPLDLFM 678
>LTK_HUMAN (P29376) Leukocyte tyrosine kinase receptor precursor (EC 2.7.10.1)| (Protein tyrosine kinase 1) Length = 864 Score = 44.3 bits (103), Expect = 3e-04 Identities = 27/87 (31%), Positives = 48/87 (55%), Gaps = 7/87 (8%) Frame = +1 Query: 388 LGEGGFGVVYKGI---LPDNE---EIAVKRLSQ-SSRQGIEELKNELVLVAKLQHKNLVR 546 LG G FG VY+G+ LP + ++A+K L + S Q + E ++++K +H+N+VR Sbjct: 516 LGHGAFGEVYEGLVIGLPGDSSPLQVAIKTLPELCSPQDELDFLMEALIISKFRHQNIVR 575 Query: 547 LLGVCLEEQEKLLAYEYMPNKSLDTIL 627 +G+ L +L+ E M + + L Sbjct: 576 CVGLSLRATPRLILLELMSGGDMKSFL 602
>CDK2_MESAU (P48963) Cell division protein kinase 2 (EC 2.7.11.22)| Length = 298 Score = 44.3 bits (103), Expect = 3e-04 Identities = 27/82 (32%), Positives = 46/82 (56%), Gaps = 3/82 (3%) Frame = +1 Query: 364 DNFDERNKLGEGGFGVVYKGILP-DNEEIAVKRLS-QSSRQGIEELK-NELVLVAKLQHK 534 +NF + K+GEG +GVVYK E +A+K++ + +G+ E+ L+ +L H Sbjct: 2 ENFQKVEKIGEGTYGVVYKAKNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHP 61 Query: 535 NLVRLLGVCLEEQEKLLAYEYM 600 N+V+LL V E + L +E + Sbjct: 62 NIVKLLDVIHTENKLYLVFELL 83
>TAOK2_MOUSE (Q6ZQ29) Serine/threonine-protein kinase TAO2 (EC 2.7.11.1)| (Thousand and one amino acid protein 2) Length = 1055 Score = 44.3 bits (103), Expect = 3e-04 Identities = 26/89 (29%), Positives = 46/89 (51%), Gaps = 4/89 (4%) Frame = +1 Query: 370 FDERNKLGEGGFGVVY-KGILPDNEEIAVKRLSQSSRQGIE---ELKNELVLVAKLQHKN 537 F + ++G G FG VY + ++E +A+K++S S +Q E ++ E+ + KL+H N Sbjct: 28 FSDLREIGHGSFGAVYFARDVRNSEVVAIKKMSYSGKQSNEKWQDIIKEVRFLQKLRHPN 87 Query: 538 LVRLLGVCLEEQEKLLAYEYMPNKSLDTI 624 ++ G L E L EY + D + Sbjct: 88 TIQYRGCYLREHTAWLVMEYCLGSASDLL 116
>CDKL2_RAT (Q5XIT0) Cyclin-dependent kinase-like 2 (EC 2.7.11.22)| Length = 507 Score = 44.3 bits (103), Expect = 3e-04 Identities = 26/90 (28%), Positives = 51/90 (56%), Gaps = 3/90 (3%) Frame = +1 Query: 364 DNFDERNKLGEGGFGVVYKGILPDNEEI-AVKRLSQSSRQGIEE--LKNELVLVAKLQHK 534 + ++ +GEG +G+V K D+ I A+K+ +S + + E+ L+ +L+H+ Sbjct: 2 EKYENLGLVGEGSYGMVMKCRNKDSGRIVAIKKFLESDDDKMVKKIAMREIKLLKQLRHE 61 Query: 535 NLVRLLGVCLEEQEKLLAYEYMPNKSLDTI 624 NLV LL VC +++ L +E++ + LD + Sbjct: 62 NLVNLLEVCKKKKRWYLVFEFVDHTILDDL 91
>BUR1_ASHGO (Q75D46) Serine/threonine-protein kinase BUR1 (EC 2.7.11.22) (EC| 2.7.11.23) Length = 753 Score = 44.3 bits (103), Expect = 3e-04 Identities = 23/82 (28%), Positives = 46/82 (56%), Gaps = 3/82 (3%) Frame = +1 Query: 367 NFDERNKLGEGGFGVVYKGI-LPDNEEIAVKRLSQSSRQGIEEL--KNELVLVAKLQHKN 537 N+ E KLG+G FG VY+G+ L ++A+K++ + + + + E+ ++ +L H+N Sbjct: 55 NYKEEKKLGQGTFGEVYRGVHLATQRQVAMKKILVKTENDLFPITAQREITILKRLNHRN 114 Query: 538 LVRLLGVCLEEQEKLLAYEYMP 603 +V+L+ + Y+Y P Sbjct: 115 VVQLIE---------MVYDYPP 127
>CDC2_RAT (P39951) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1) Length = 297 Score = 44.3 bits (103), Expect = 3e-04 Identities = 28/93 (30%), Positives = 54/93 (58%), Gaps = 6/93 (6%) Frame = +1 Query: 364 DNFDERNKLGEGGFGVVYKG-ILPDNEEIAVKRLS-QSSRQGIEELK-NELVLVAKLQHK 534 +++ + K+GEG +GVVYKG + +A+K++ +S +G+ E+ L+ +L+H Sbjct: 2 EDYIKIEKIGEGTYGVVYKGRHRTTGQIVAMKKIRLESEEEGVPSTAIREISLLKELRHP 61 Query: 535 NLVRLLGVCLEEQEKLLAYEYMP---NKSLDTI 624 N+V L V +++ L +E++ K LD+I Sbjct: 62 NIVSLQDVLMQDSRLYLIFEFLSMDLKKYLDSI 94
>EPHA2_HUMAN (P29317) Ephrin type-A receptor 2 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor ECK) (Epithelial cell kinase) Length = 976 Score = 44.3 bits (103), Expect = 3e-04 Identities = 28/87 (32%), Positives = 47/87 (54%), Gaps = 7/87 (8%) Frame = +1 Query: 388 LGEGGFGVVYKGILPDNE-----EIAVKRLSQ--SSRQGIEELKNELVLVAKLQHKNLVR 546 +G G FG VYKG+L + +A+K L + +Q ++ L E ++ + H N++R Sbjct: 619 IGAGEFGEVYKGMLKTSSGKKEVPVAIKTLKAGYTEKQRVDFL-GEAGIMGQFSHHNIIR 677 Query: 547 LLGVCLEEQEKLLAYEYMPNKSLDTIL 627 L GV + + ++ EYM N +LD L Sbjct: 678 LEGVISKYKPMMIITEYMENGALDKFL 704
>CDKL2_RABIT (Q9TTK0) Cyclin-dependent kinase-like 2 (EC 2.7.11.22)| (Serine/threonine-protein kinase KKIAMRE) Length = 566 Score = 44.3 bits (103), Expect = 3e-04 Identities = 26/90 (28%), Positives = 51/90 (56%), Gaps = 3/90 (3%) Frame = +1 Query: 364 DNFDERNKLGEGGFGVVYKGILPDNEEI-AVKRLSQSSRQGIEE--LKNELVLVAKLQHK 534 + ++ +GEG +G+V K D+ I A+K+ +S + + E+ L+ +L+H+ Sbjct: 2 EKYENLGLVGEGSYGMVMKCRNKDSGRIVAIKKFLESDDDKMVKKIAMREIKLLKQLRHE 61 Query: 535 NLVRLLGVCLEEQEKLLAYEYMPNKSLDTI 624 NLV LL VC +++ L +E++ + LD + Sbjct: 62 NLVNLLEVCKKKKRWYLVFEFVDHTILDDL 91
>LCK_MOUSE (P06240) Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2)| (p56-LCK) (Lymphocyte cell-specific protein-tyrosine kinase) (LSK) Length = 508 Score = 44.3 bits (103), Expect = 3e-04 Identities = 30/77 (38%), Positives = 41/77 (53%) Frame = +1 Query: 385 KLGEGGFGVVYKGILPDNEEIAVKRLSQSSRQGIEELKNELVLVAKLQHKNLVRLLGVCL 564 +LG G FG V+ G + ++AVK L Q S + E L+ +LQH LVRL V Sbjct: 249 RLGAGQFGEVWMGYYNGHTKVAVKSLKQGS-MSPDAFLAEANLMKQLQHPRLVRLYAVVT 307 Query: 565 EEQEKLLAYEYMPNKSL 615 +E ++ EYM N SL Sbjct: 308 QEPIYIIT-EYMENGSL 323
>CDKL2_MOUSE (Q9QUK0) Cyclin-dependent kinase-like 2 (EC 2.7.11.22)| (Serine/threonine-protein kinase KKIAMRE) Length = 568 Score = 44.3 bits (103), Expect = 3e-04 Identities = 26/90 (28%), Positives = 51/90 (56%), Gaps = 3/90 (3%) Frame = +1 Query: 364 DNFDERNKLGEGGFGVVYKGILPDNEEI-AVKRLSQSSRQGIEE--LKNELVLVAKLQHK 534 + ++ +GEG +G+V K D+ I A+K+ +S + + E+ L+ +L+H+ Sbjct: 2 EKYENLGLVGEGSYGMVMKCRNKDSGRIVAIKKFLESDDDKMVKKIAMREIKLLKQLRHE 61 Query: 535 NLVRLLGVCLEEQEKLLAYEYMPNKSLDTI 624 NLV LL VC +++ L +E++ + LD + Sbjct: 62 NLVNLLEVCKKKKRWYLVFEFVDHTILDDL 91
>ERBB2_MESAU (Q60553) Receptor tyrosine-protein kinase erbB-2 precursor (EC| 2.7.10.1) (p185erbB2) (C-erbB-2) (NEU proto-oncogene) Length = 1254 Score = 43.9 bits (102), Expect = 4e-04 Identities = 30/78 (38%), Positives = 46/78 (58%), Gaps = 6/78 (7%) Frame = +1 Query: 388 LGEGGFGVVYKGI-LPDNEE----IAVKRLSQ-SSRQGIEELKNELVLVAKLQHKNLVRL 549 LG G FG VYKGI +PD E +A+K L + +S + +E+ +E ++A L + RL Sbjct: 726 LGSGAFGTVYKGIWIPDGENVKIPVAIKVLRENTSPKANKEILDEAYVMAGLGSPYVSRL 785 Query: 550 LGVCLEEQEKLLAYEYMP 603 LG+CL +L+ + MP Sbjct: 786 LGICLTSTVQLVT-QLMP 802
>MET_CALMO (Q2QLC0) Hepatocyte growth factor receptor precursor (EC 2.7.10.1)| (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met) Length = 1381 Score = 43.9 bits (102), Expect = 4e-04 Identities = 28/82 (34%), Positives = 43/82 (52%), Gaps = 6/82 (7%) Frame = +1 Query: 388 LGEGGFGVVYKGILPDNE----EIAVKRLSQSSRQG-IEELKNELVLVAKLQHKNLVRLL 552 +G G FG VY G L DN+ AVK L++ + G + + E +++ H N++ LL Sbjct: 1084 IGRGHFGCVYHGTLLDNDGKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNVLSLL 1143 Query: 553 GVCL-EEQEKLLAYEYMPNKSL 615 G+CL E L+ YM + L Sbjct: 1144 GICLRSEGSPLVVLPYMKHGDL 1165
>MET_CALJA (Q2QLG5) Hepatocyte growth factor receptor precursor (EC 2.7.10.1)| (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met) Length = 1381 Score = 43.9 bits (102), Expect = 4e-04 Identities = 28/82 (34%), Positives = 43/82 (52%), Gaps = 6/82 (7%) Frame = +1 Query: 388 LGEGGFGVVYKGILPDNE----EIAVKRLSQSSRQG-IEELKNELVLVAKLQHKNLVRLL 552 +G G FG VY G L DN+ AVK L++ + G + + E +++ H N++ LL Sbjct: 1084 IGRGHFGCVYHGTLLDNDGKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNVLSLL 1143 Query: 553 GVCL-EEQEKLLAYEYMPNKSL 615 G+CL E L+ YM + L Sbjct: 1144 GICLRSEGSPLVVLPYMKHGDL 1165
>MET_PONPY (Q2IBD8) Hepatocyte growth factor receptor precursor (EC 2.7.10.1)| (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met) Length = 1390 Score = 43.9 bits (102), Expect = 4e-04 Identities = 28/82 (34%), Positives = 43/82 (52%), Gaps = 6/82 (7%) Frame = +1 Query: 388 LGEGGFGVVYKGILPDNE----EIAVKRLSQSSRQG-IEELKNELVLVAKLQHKNLVRLL 552 +G G FG VY G L DN+ AVK L++ + G + + E +++ H N++ LL Sbjct: 1084 IGRGHFGCVYHGTLLDNDGKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNVLSLL 1143 Query: 553 GVCL-EEQEKLLAYEYMPNKSL 615 G+CL E L+ YM + L Sbjct: 1144 GICLRSEGSPLVVLPYMKHGDL 1165
>MET_PANTR (Q2QLF1) Hepatocyte growth factor receptor precursor (EC 2.7.10.1)| (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met) Length = 1390 Score = 43.9 bits (102), Expect = 4e-04 Identities = 28/82 (34%), Positives = 43/82 (52%), Gaps = 6/82 (7%) Frame = +1 Query: 388 LGEGGFGVVYKGILPDNE----EIAVKRLSQSSRQG-IEELKNELVLVAKLQHKNLVRLL 552 +G G FG VY G L DN+ AVK L++ + G + + E +++ H N++ LL Sbjct: 1084 IGRGHFGCVYHGTLLDNDGKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNVLSLL 1143 Query: 553 GVCL-EEQEKLLAYEYMPNKSL 615 G+CL E L+ YM + L Sbjct: 1144 GICLRSEGSPLVVLPYMKHGDL 1165
>MET_HUMAN (P08581) Hepatocyte growth factor receptor precursor (EC 2.7.10.1)| (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met) Length = 1390 Score = 43.9 bits (102), Expect = 4e-04 Identities = 28/82 (34%), Positives = 43/82 (52%), Gaps = 6/82 (7%) Frame = +1 Query: 388 LGEGGFGVVYKGILPDNE----EIAVKRLSQSSRQG-IEELKNELVLVAKLQHKNLVRLL 552 +G G FG VY G L DN+ AVK L++ + G + + E +++ H N++ LL Sbjct: 1084 IGRGHFGCVYHGTLLDNDGKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNVLSLL 1143 Query: 553 GVCL-EEQEKLLAYEYMPNKSL 615 G+CL E L+ YM + L Sbjct: 1144 GICLRSEGSPLVVLPYMKHGDL 1165
>BMPR2_MOUSE (O35607) Bone morphogenetic protein receptor type-2 precursor (EC| 2.7.11.30) (Bone morphogenetic protein receptor type II) (BMP type II receptor) (BMPR-II) (BRK-3) Length = 1038 Score = 43.9 bits (102), Expect = 4e-04 Identities = 32/89 (35%), Positives = 42/89 (47%), Gaps = 5/89 (5%) Frame = +1 Query: 364 DNFDERNKLGEGGFGVVYKGILPDNEEIAVKRLSQSSRQGIEELKNELVLVAKLQHKNLV 543 DN +G G +G VYKG L D +AVK S ++RQ KN + V ++H N+ Sbjct: 201 DNLKLLELIGRGRYGAVYKGSL-DERPVAVKVFSFANRQNFINEKN-IYRVPLMEHDNIA 258 Query: 544 RLLG-----VCLEEQEKLLAYEYMPNKSL 615 R + E LL EY PN SL Sbjct: 259 RFIVGDERLTADGRMEYLLVMEYYPNGSL 287
>BMPR2_HUMAN (Q13873) Bone morphogenetic protein receptor type-2 precursor (EC| 2.7.11.30) (Bone morphogenetic protein receptor type II) (BMP type II receptor) (BMPR-II) Length = 1038 Score = 43.9 bits (102), Expect = 4e-04 Identities = 32/89 (35%), Positives = 42/89 (47%), Gaps = 5/89 (5%) Frame = +1 Query: 364 DNFDERNKLGEGGFGVVYKGILPDNEEIAVKRLSQSSRQGIEELKNELVLVAKLQHKNLV 543 DN +G G +G VYKG L D +AVK S ++RQ KN + V ++H N+ Sbjct: 201 DNLKLLELIGRGRYGAVYKGSL-DERPVAVKVFSFANRQNFINEKN-IYRVPLMEHDNIA 258 Query: 544 RLL-----GVCLEEQEKLLAYEYMPNKSL 615 R + E LL EY PN SL Sbjct: 259 RFIVGDERVTADGRMEYLLVMEYYPNGSL 287
>YR831_MIMIV (Q7T6Y2) Putative serine/threonine-protein kinase/receptor R831| precursor (EC 2.7.11.1) Length = 1624 Score = 43.9 bits (102), Expect = 4e-04 Identities = 25/92 (27%), Positives = 51/92 (55%), Gaps = 5/92 (5%) Frame = +1 Query: 367 NFDERN---KLGEGGFGVVYKGILPDNEEIAVKRLSQS--SRQGIEELKNELVLVAKLQH 531 N+DE + ++G G +G+V+ G ++AVK+ + S + E + E+ +++L+H Sbjct: 1360 NYDEISIGKQIGLGSYGIVFNGKWK-GVDVAVKKFVKQKLSETQLLEFRAEMAFLSELKH 1418 Query: 532 KNLVRLLGVCLEEQEKLLAYEYMPNKSLDTIL 627 N+V +G C+++ + EYM +L +L Sbjct: 1419 SNIVTFIGACIKKPNICIVTEYMRMGNLRDVL 1450 Score = 37.4 bits (85), Expect = 0.038 Identities = 25/82 (30%), Positives = 39/82 (47%), Gaps = 2/82 (2%) Frame = +1 Query: 388 LGEGGFGVVYKGILPDNEEIAVKRLSQS--SRQGIEELKNELVLVAKLQHKNLVRLLGVC 561 LG GG+G VYK I E+AVK +S S+ E+ ++ L+H N+V + Sbjct: 792 LGTGGYGEVYKSIW-KGTEVAVKLISSKHVSKDMERSFFEEVKIMTSLRHPNVVLFMAAS 850 Query: 562 LEEQEKLLAYEYMPNKSLDTIL 627 + + E+M SL +L Sbjct: 851 TKSPNMCIVMEFMSLGSLYDLL 872
>SRMS_MOUSE (Q62270) Tyrosine-protein kinase Srms (EC 2.7.10.2) (PTK70)| Length = 496 Score = 43.9 bits (102), Expect = 4e-04 Identities = 26/83 (31%), Positives = 45/83 (54%) Frame = +1 Query: 379 RNKLGEGGFGVVYKGILPDNEEIAVKRLSQSSRQGIEELKNELVLVAKLQHKNLVRLLGV 558 R KLGEG FG V++G+ + +AVK + +S+ + +L E+ + L+H+ L+RL + Sbjct: 237 RRKLGEGFFGEVWEGLWLGSIPVAVK-VIKSADMKLADLTKEIEALKSLRHERLIRLHAI 295 Query: 559 CLEEQEKLLAYEYMPNKSLDTIL 627 C + + E M +L L Sbjct: 296 CSLGEPVYIVTELMGKGNLQVYL 318
>MET_OTOGA (Q2QLH6) Hepatocyte growth factor receptor precursor (EC 2.7.10.1)| (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met) Length = 1382 Score = 43.9 bits (102), Expect = 4e-04 Identities = 28/82 (34%), Positives = 43/82 (52%), Gaps = 6/82 (7%) Frame = +1 Query: 388 LGEGGFGVVYKGILPDNE----EIAVKRLSQSSRQG-IEELKNELVLVAKLQHKNLVRLL 552 +G G FG VY G L DN+ AVK L++ + G + + E +++ H N++ LL Sbjct: 1085 IGRGHFGCVYHGTLLDNDGKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNVLSLL 1144 Query: 553 GVCL-EEQEKLLAYEYMPNKSL 615 G+CL E L+ YM + L Sbjct: 1145 GICLRSEGSPLVVLPYMKHGDL 1166
>MET_MICMU (Q2QL89) Hepatocyte growth factor receptor precursor (EC 2.7.10.1)| (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met) Length = 1382 Score = 43.9 bits (102), Expect = 4e-04 Identities = 28/82 (34%), Positives = 43/82 (52%), Gaps = 6/82 (7%) Frame = +1 Query: 388 LGEGGFGVVYKGILPDNE----EIAVKRLSQSSRQG-IEELKNELVLVAKLQHKNLVRLL 552 +G G FG VY G L DN+ AVK L++ + G + + E +++ H N++ LL Sbjct: 1085 IGRGHFGCVYHGTLLDNDGKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNVLSLL 1144 Query: 553 GVCL-EEQEKLLAYEYMPNKSL 615 G+CL E L+ YM + L Sbjct: 1145 GICLRSEGSPLVVLPYMKHGDL 1166
>CDC2_PONPY (Q5RCH1) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1) Length = 297 Score = 43.9 bits (102), Expect = 4e-04 Identities = 27/93 (29%), Positives = 53/93 (56%), Gaps = 6/93 (6%) Frame = +1 Query: 364 DNFDERNKLGEGGFGVVYKG-ILPDNEEIAVKRLS-QSSRQGIEELK-NELVLVAKLQHK 534 +++ + K+GEG +GVVYKG + + +K++ +S +G+ E+ L+ +L+H Sbjct: 2 EDYTKIEKIGEGTYGVVYKGRHKTTGQVVTMKKIRLESEEEGVPSTAIREISLLKELRHP 61 Query: 535 NLVRLLGVCLEEQEKLLAYEYMP---NKSLDTI 624 N+V L V +++ L +E++ K LD+I Sbjct: 62 NIVSLQDVLMQDSRLYLIFEFLSMDLKKYLDSI 94
>CDC2_MOUSE (P11440) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1) Length = 297 Score = 43.9 bits (102), Expect = 4e-04 Identities = 28/93 (30%), Positives = 54/93 (58%), Gaps = 6/93 (6%) Frame = +1 Query: 364 DNFDERNKLGEGGFGVVYKG-ILPDNEEIAVKRLS-QSSRQGIEELK-NELVLVAKLQHK 534 +++ + K+GEG +GVVYKG + +A+K++ +S +G+ E+ L+ +L+H Sbjct: 2 EDYIKIEKIGEGTYGVVYKGRHRVTGQIVAMKKIRLESEEEGVPSTAIREISLLKELRHP 61 Query: 535 NLVRLLGVCLEEQEKLLAYEYMP---NKSLDTI 624 N+V L V +++ L +E++ K LD+I Sbjct: 62 NIVSLQDVLMQDSRLYLIFEFLSMDLKKYLDSI 94
>CDKL2_MACFA (Q4R7T5) Cyclin-dependent kinase-like 2 (EC 2.7.11.22)| Length = 570 Score = 43.9 bits (102), Expect = 4e-04 Identities = 26/90 (28%), Positives = 50/90 (55%), Gaps = 3/90 (3%) Frame = +1 Query: 364 DNFDERNKLGEGGFGVVYKGILPDNEEI-AVKRLSQSSRQGIEE--LKNELVLVAKLQHK 534 + ++ +GEG +G+V K D I A+K+ +S + + E+ L+ +L+H+ Sbjct: 2 EKYENLGLVGEGSYGMVVKCRNKDTGRIVAIKKFLESDDDKMVKKIAMREIKLLKQLRHE 61 Query: 535 NLVRLLGVCLEEQEKLLAYEYMPNKSLDTI 624 NLV LL VC +++ L +E++ + LD + Sbjct: 62 NLVNLLEVCKKKKRWYLVFEFVDHTILDDL 91
>PAKM_DROME (Q9VXE5) Serine/threonine-protein kinase PAK mbt (EC 2.7.11.1)| (p21-activated kinase-related protein) (Protein mushroom bodies tiny) Length = 639 Score = 43.9 bits (102), Expect = 4e-04 Identities = 29/91 (31%), Positives = 44/91 (48%), Gaps = 3/91 (3%) Frame = +1 Query: 364 DNFDERNKLGEGGFGVVYKGILPDNE---EIAVKRLSQSSRQGIEELKNELVLVAKLQHK 534 +N D NK+GEG G V I D ++AVK++ +Q E L NE+V++ H Sbjct: 366 ENLDHFNKIGEGSTGTVC--IATDKSTGRQVAVKKMDLRKQQRRELLFNEVVIMRDYHHP 423 Query: 535 NLVRLLGVCLEEQEKLLAYEYMPNKSLDTIL 627 N+V L E + EY+ +L I+ Sbjct: 424 NIVETYSSFLVNDELWVVMEYLEGGALTDIV 454
>CDKL2_PONPY (Q5R754) Cyclin-dependent kinase-like 2 (EC 2.7.11.22)| Length = 493 Score = 43.9 bits (102), Expect = 4e-04 Identities = 26/90 (28%), Positives = 50/90 (55%), Gaps = 3/90 (3%) Frame = +1 Query: 364 DNFDERNKLGEGGFGVVYKGILPDNEEI-AVKRLSQSSRQGIEE--LKNELVLVAKLQHK 534 + ++ +GEG +G+V K D I A+K+ +S + + E+ L+ +L+H+ Sbjct: 2 EKYENLGLVGEGSYGMVMKCRNKDTGRIVAIKKFLESDDDKMVKKIAMREIKLLKQLRHE 61 Query: 535 NLVRLLGVCLEEQEKLLAYEYMPNKSLDTI 624 NLV LL VC +++ L +E++ + LD + Sbjct: 62 NLVNLLEVCKKKKRWYLVFEFVDHTILDDL 91
>CDKL2_HUMAN (Q92772) Cyclin-dependent kinase-like 2 (EC 2.7.11.22)| (Serine/threonine-protein kinase KKIAMRE) (Protein kinase p56 KKIAMRE) Length = 493 Score = 43.9 bits (102), Expect = 4e-04 Identities = 26/90 (28%), Positives = 50/90 (55%), Gaps = 3/90 (3%) Frame = +1 Query: 364 DNFDERNKLGEGGFGVVYKGILPDNEEI-AVKRLSQSSRQGIEE--LKNELVLVAKLQHK 534 + ++ +GEG +G+V K D I A+K+ +S + + E+ L+ +L+H+ Sbjct: 2 EKYENLGLVGEGSYGMVMKCRNKDTGRIVAIKKFLESDDDKMVKKIAMREIKLLKQLRHE 61 Query: 535 NLVRLLGVCLEEQEKLLAYEYMPNKSLDTI 624 NLV LL VC +++ L +E++ + LD + Sbjct: 62 NLVNLLEVCKKKKRWYLVFEFVDHTILDDL 91
>IGF1R_XENLA (O73798) Insulin-like growth factor 1 receptor precursor (EC| 2.7.10.1) (xIGF-1R) (xIGFR) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain] Length = 1358 Score = 43.9 bits (102), Expect = 4e-04 Identities = 33/99 (33%), Positives = 53/99 (53%), Gaps = 8/99 (8%) Frame = +1 Query: 355 VATDNFDERNKLGEGGFGVVY----KGILPDNEE--IAVKRLSQ--SSRQGIEELKNELV 510 V + +LG+G FG+VY KG++ D E +A+K +++ S R+ IE L NE Sbjct: 990 VPREKITMNRELGQGSFGMVYEGIAKGVVKDEAETKVAIKTVNEAASMRERIEFL-NEAS 1048 Query: 511 LVAKLQHKNLVRLLGVCLEEQEKLLAYEYMPNKSLDTIL 627 ++ + ++VRLLGV + Q L+ E M L + L Sbjct: 1049 VMKEFNCHHVVRLLGVVSQGQPTLVIMELMTRGDLKSYL 1087
>IRAK2_HUMAN (O43187) Interleukin-1 receptor-associated kinase-like 2 (IRAK-2)| Length = 590 Score = 43.5 bits (101), Expect = 5e-04 Identities = 30/90 (33%), Positives = 45/90 (50%), Gaps = 4/90 (4%) Frame = +1 Query: 358 ATDNFDERNKLGEGGFGVVYKGILPDNEEIAVKRLSQ---SSRQGIEEL-KNELVLVAKL 525 ATD+F++ K+ +G F VY+G + K+L + SS IE + EL + + Sbjct: 206 ATDDFNQNRKISQGTFADVYRGHR-HGKPFVFKKLRETACSSPGSIERFFQAELQICLRC 264 Query: 526 QHKNLVRLLGVCLEEQEKLLAYEYMPNKSL 615 H N++ +LG C Q Y YM N SL Sbjct: 265 CHPNVLPVLGFCAARQFHSFIYPYMANGSL 294
>INSR_DROME (P09208) Insulin-like receptor precursor (EC 2.7.10.1) (DIR) (DInr)| (dIRH) [Contains: Insulin-like receptor alpha subunit; Insulin-like receptor beta 1 subunit; Insulin-like receptor beta 2 subunit] Length = 2144 Score = 43.5 bits (101), Expect = 5e-04 Identities = 31/98 (31%), Positives = 51/98 (52%), Gaps = 7/98 (7%) Frame = +1 Query: 355 VATDNFDERNKLGEGGFGVVYKGIL---PDN---EEIAVKRLSQSSR-QGIEELKNELVL 513 V +N + LG+G FG+VY+GIL P N E A+K +++++ + +E + Sbjct: 1366 VLRENIIQLAPLGQGSFGMVYEGILKSFPPNGVDRECAIKTVNENATDRERTNFLSEASV 1425 Query: 514 VAKLQHKNLVRLLGVCLEEQEKLLAYEYMPNKSLDTIL 627 + + ++VRLLGVC Q L+ E M L + L Sbjct: 1426 MKEFDTYHVVRLLGVCSRGQPALVVMELMKKGDLKSYL 1463
>TAOK3_MOUSE (Q8BYC6) Serine/threonine-protein kinase TAO3 (EC 2.7.11.1)| (Thousand and one amino acid protein 3) Length = 898 Score = 43.5 bits (101), Expect = 5e-04 Identities = 27/89 (30%), Positives = 45/89 (50%), Gaps = 4/89 (4%) Frame = +1 Query: 370 FDERNKLGEGGFGVVYKGI-LPDNEEIAVKRLSQSSRQGIE---ELKNELVLVAKLQHKN 537 F + +++G G FG VY NE +AVK++S S +Q E ++ E+ + +L+H N Sbjct: 24 FIDLHEIGHGSFGAVYFATNAHTNEVVAVKKMSYSGKQTHEKWQDILKEVKFLQQLKHPN 83 Query: 538 LVRLLGVCLEEQEKLLAYEYMPNKSLDTI 624 + G L+E L EY + D + Sbjct: 84 TIEYKGCYLKEHTAWLVMEYCLGSASDLL 112
>TAOK1_RAT (O88664) Serine/threonine-protein kinase TAO1 (EC 2.7.11.1)| (Thousand and one amino acid protein 1) Length = 1001 Score = 43.5 bits (101), Expect = 5e-04 Identities = 25/89 (28%), Positives = 44/89 (49%), Gaps = 4/89 (4%) Frame = +1 Query: 370 FDERNKLGEGGFGVVY-KGILPDNEEIAVKRLSQSSRQGIE---ELKNELVLVAKLQHKN 537 F + ++G G FG VY + NE +A+K++S S +Q E ++ E+ + +++H N Sbjct: 28 FTDLREIGHGSFGAVYFARDVRTNEVVAIKKMSYSGKQSTEKWQDIIKEVKFLQRIKHPN 87 Query: 538 LVRLLGVCLEEQEKLLAYEYMPNKSLDTI 624 + G L E L EY + D + Sbjct: 88 SIEYKGCYLREHTAWLVMEYCLGSASDLL 116
>TAOK1_MOUSE (Q5F2E8) Serine/threonine-protein kinase TAO1 (EC 2.7.11.1)| (Thousand and one amino acid protein 1) Length = 1001 Score = 43.5 bits (101), Expect = 5e-04 Identities = 25/89 (28%), Positives = 44/89 (49%), Gaps = 4/89 (4%) Frame = +1 Query: 370 FDERNKLGEGGFGVVY-KGILPDNEEIAVKRLSQSSRQGIE---ELKNELVLVAKLQHKN 537 F + ++G G FG VY + NE +A+K++S S +Q E ++ E+ + +++H N Sbjct: 28 FTDLREIGHGSFGAVYFARDVRTNEVVAIKKMSYSGKQSTEKWQDIIKEVKFLQRIKHPN 87 Query: 538 LVRLLGVCLEEQEKLLAYEYMPNKSLDTI 624 + G L E L EY + D + Sbjct: 88 SIEYKGCYLREHTAWLVMEYCLGSASDLL 116
>TAOK1_HUMAN (Q7L7X3) Serine/threonine-protein kinase TAO1 (EC 2.7.11.1)| (Thousand and one amino acid protein 1) (STE20-like kinase PSK2) (Kinase from chicken homolog B) (hKFC-B) Length = 1001 Score = 43.5 bits (101), Expect = 5e-04 Identities = 25/89 (28%), Positives = 44/89 (49%), Gaps = 4/89 (4%) Frame = +1 Query: 370 FDERNKLGEGGFGVVY-KGILPDNEEIAVKRLSQSSRQGIE---ELKNELVLVAKLQHKN 537 F + ++G G FG VY + NE +A+K++S S +Q E ++ E+ + +++H N Sbjct: 28 FTDLREIGHGSFGAVYFARDVRTNEVVAIKKMSYSGKQSTEKWQDIIKEVKFLQRIKHPN 87 Query: 538 LVRLLGVCLEEQEKLLAYEYMPNKSLDTI 624 + G L E L EY + D + Sbjct: 88 SIEYKGCYLREHTAWLVMEYCLGSASDLL 116
>SRC42_DROME (Q9V9J3) Tyrosine-protein kinase Src42A (EC 2.7.10.2) (Dsrc41)| Length = 517 Score = 43.5 bits (101), Expect = 5e-04 Identities = 25/77 (32%), Positives = 42/77 (54%) Frame = +1 Query: 385 KLGEGGFGVVYKGILPDNEEIAVKRLSQSSRQGIEELKNELVLVAKLQHKNLVRLLGVCL 564 KLG G FG V++G+ + +A+K L +S ++ E ++ KL+H L++L VC Sbjct: 253 KLGSGQFGDVWEGLWNNTTPVAIKTL-KSGTMDPKDFLAEAQIMKKLRHTKLIQLYAVCT 311 Query: 565 EEQEKLLAYEYMPNKSL 615 E+ + E M + SL Sbjct: 312 VEEPIYIITELMKHGSL 328
>FYN_MOUSE (P39688) Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2)| (p59-Fyn) Length = 533 Score = 43.5 bits (101), Expect = 5e-04 Identities = 32/93 (34%), Positives = 45/93 (48%) Frame = +1 Query: 355 VATDNFDERNKLGEGGFGVVYKGILPDNEEIAVKRLSQSSRQGIEELKNELVLVAKLQHK 534 VA D+ KLG+G F V+ G N ++A+K L + E E ++ KL+H Sbjct: 262 VARDSLFLEKKLGQGCFAEVWLGTWNGNTKVAIKTLKPGT-MSPESFLEEAQIMKKLKHD 320 Query: 535 NLVRLLGVCLEEQEKLLAYEYMPNKSLDTILFD 633 LV+L V EE ++ EYM SL L D Sbjct: 321 KLVQLYAVVSEEPIYIVT-EYMSKGSLLDFLKD 352 Database: uniprot_sprot.fasta Posted date: May 25, 2006 5:36 PM Number of letters in database: 80,573,946 Number of sequences in database: 219,361 Lambda K H 0.318 0.135 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 82,456,293 Number of Sequences: 219361 Number of extensions: 1526149 Number of successful extensions: 6080 Number of sequences better than 10.0: 500 Number of HSP's better than 10.0 without gapping: 5455 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 5738 length of database: 80,573,946 effective HSP length: 107 effective length of database: 57,102,319 effective search space used: 5938641176 frameshift window, decay const: 50, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
