Clone Name | baaln02 |
---|---|
Clone Library Name | barley_pub |
>C72A1_CATRO (Q05047) Cytochrome P450 72A1 (EC 1.3.3.9) (CYPLXXII) (Secologanin| synthase) (SLS) Length = 524 Score = 88.2 bits (217), Expect = 2e-17 Identities = 50/151 (33%), Positives = 79/151 (52%), Gaps = 1/151 (0%) Frame = +2 Query: 134 WDYAVVRLVW-RPYAMSKWFREQGIHGPSYRFLKGCNEDVRSIKEETDRLVLDVGDHKYL 310 W + V+ W P + K R+QG G YRFL G ++ + +E ++ ++ + Sbjct: 23 WAWRVLDWAWFTPKRIEKRLRQQGFRGNPYRFLVGDVKESGKMHQEALSKPMEF-NNDIV 81 Query: 311 PRIAPHYLKWRAQHGEPFLYWHGPQPRICIFEYEMARQILSTKSGHFVKNDAHPTLLALV 490 PR+ PH +G W G PRI + E E+ +++L+ S + D H L+ + Sbjct: 82 PRLMPHINHTINTYGRNSFTWMGRIPRIHVMEPELIKEVLTHSSKYQKNFDVHNPLVKFL 141 Query: 491 GKGLGFMEGADWVRHRRIINPVFTIDKLKMM 583 G+G EGA W +HRRII+P FT++KLK M Sbjct: 142 LTGVGSFEGAKWSKHRRIISPAFTLEKLKSM 172
>CP4X1_HUMAN (Q8N118) Cytochrome P450 4X1 (EC 1.14.14.1) (CYPIVX1)| Length = 509 Score = 46.2 bits (108), Expect = 7e-05 Identities = 26/81 (32%), Positives = 44/81 (54%), Gaps = 3/81 (3%) Frame = +2 Query: 362 FLYWHGP-QPRICIFEYEMARQILSTKS--GHFVKNDAHPTLLALVGKGLGFMEGADWVR 532 F +W GP Q CI++ + A+ +LS +++ + P L+GKGL ++G W + Sbjct: 80 FPFWIGPFQAFFCIYDPDYAKTLLSRTDPKSQYLQKFSPP----LLGKGLAALDGPKWFQ 135 Query: 533 HRRIINPVFTIDKLKMMTKTM 595 HRR++ P F + LK + M Sbjct: 136 HRRLLTPGFHFNILKAYIEVM 156
>CP4F1_RAT (P33274) Cytochrome P450 4F1 (EC 1.14.14.1) (CYPIVF1) (P450-A3)| Length = 524 Score = 43.1 bits (100), Expect = 6e-04 Identities = 28/82 (34%), Positives = 40/82 (48%), Gaps = 2/82 (2%) Frame = +2 Query: 362 FLYWHGPQ-PRICIFEYEMARQILSTKSGHFVKNDAHPTLLA-LVGKGLGFMEGADWVRH 535 FL W GP P I + ++ R IL+ + +K+ T+L +G GL G W RH Sbjct: 88 FLMWIGPMVPVITLCHSDIVRSILNASAAVALKDVIFYTILKPWLGDGLLVSAGDKWSRH 147 Query: 536 RRIINPVFTIDKLKMMTKTMLD 601 RR++ P F + LK K D Sbjct: 148 RRMLTPAFHFNILKPYVKIFND 169
>CP4AC_MOUSE (Q91WL5) Cytochrome P450 4A12 (EC 1.14.14.1) (CYPIVA12)| Length = 508 Score = 43.1 bits (100), Expect = 6e-04 Identities = 23/75 (30%), Positives = 39/75 (52%) Frame = +2 Query: 377 GPQPRICIFEYEMARQILSTKSGHFVKNDAHPTLLALVGKGLGFMEGADWVRHRRIINPV 556 G + RI +++ + + IL N ++ L +G+GL ++G W +HRR++ P Sbjct: 90 GSKVRIQVYDPDYMKLILGRSDPK--ANGSYRFLAPWIGRGLLLLDGQTWFQHRRMLTPA 147 Query: 557 FTIDKLKMMTKTMLD 601 F D LK T+ M D Sbjct: 148 FHYDILKPYTEIMAD 162
>CP3AI_RAT (Q64581) Cytochrome P450 3A18 (EC 1.14.14.1) (CYPIIIA18)| (P450(6)beta-2) Length = 497 Score = 42.0 bits (97), Expect = 0.001 Identities = 23/86 (26%), Positives = 42/86 (48%) Frame = +2 Query: 347 QHGEPFLYWHGPQPRICIFEYEMARQILSTKSGHFVKNDAHPTLLALVGKGLGFMEGADW 526 ++G+ + ++ GPQP + I + E+ + +L + N + + K + E +W Sbjct: 67 KYGKIWGFYEGPQPFLAIMDPEIIKMVLVKECYSVFTNRRCFGPMGFMKKAITMSEDEEW 126 Query: 527 VRHRRIINPVFTIDKLKMMTKTMLDF 604 R R I++P FT KLK M M + Sbjct: 127 KRLRTILSPTFTSGKLKEMFPLMRQY 152
>CP4A2_RAT (P20816) Cytochrome P450 4A2 precursor (EC 1.14.15.3) (CYPIVA2)| (Lauric acid omega-hydroxylase) (P450-LA-omega 2) (P450 K-5) (P-450 K-2) Length = 504 Score = 41.6 bits (96), Expect = 0.002 Identities = 28/104 (26%), Positives = 44/104 (42%), Gaps = 3/104 (2%) Frame = +2 Query: 299 HKYLPRIAPHYLKWRAQHGEPFLYW-HGPQPRICIFEYEMARQILSTKSGHFVKNDAHP- 472 H R L W + L W G R+ +++ + + +L ++D P Sbjct: 62 HNLKDREFQQVLTWVEKFPGACLQWLSGSTARVLLYDPDYVKVVLG-------RSDPKPY 114 Query: 473 -TLLALVGKGLGFMEGADWVRHRRIINPVFTIDKLKMMTKTMLD 601 +L +G GL + G W +HRR++ P F D LK K M D Sbjct: 115 QSLAPWIGYGLLLLNGKKWFQHRRMLTPAFHYDILKPYVKIMAD 158
>CP4AA_MOUSE (O88833) Cytochrome P450 4A10 (EC 1.14.15.3) (CYPIVA10) (Lauric| acid omega-hydroxylase) (P450-LA-omega 1) (P452) Length = 509 Score = 41.6 bits (96), Expect = 0.002 Identities = 24/81 (29%), Positives = 38/81 (46%) Frame = +2 Query: 359 PFLYWHGPQPRICIFEYEMARQILSTKSGHFVKNDAHPTLLALVGKGLGFMEGADWVRHR 538 P +W G + + +++ + + IL N A+ L +G GL + G W +HR Sbjct: 86 PRWFW-GSKAYLTVYDPDYMKVILGRSDPK--ANGAYRLLAPWIGYGLLLLNGQPWFQHR 142 Query: 539 RIINPVFTIDKLKMMTKTMLD 601 R++ P F D LK K M D Sbjct: 143 RMLTPAFHYDILKPYVKNMAD 163
>CP4FE_MOUSE (Q9EP75) Cytochrome P450 4F14 (EC 1.14.13.30) (Leukotriene-B4| omega-hydroxylase) (Leukotriene-B4 20-monooxygenase) (Cytochrome P450-LTB-omega) (Cyp4f-14) Length = 524 Score = 41.6 bits (96), Expect = 0.002 Identities = 27/82 (32%), Positives = 40/82 (48%), Gaps = 2/82 (2%) Frame = +2 Query: 362 FLYWHGPQ-PRICIFEYEMARQILSTKSGHFVKNDAHPTLLA-LVGKGLGFMEGADWVRH 535 FL W GP P I + ++ R IL+ + +K+ ++L +G GL G W RH Sbjct: 88 FLMWIGPMVPVITLCHSDIVRSILNASAAVALKDVIFYSILKPWLGDGLLVSAGDKWSRH 147 Query: 536 RRIINPVFTIDKLKMMTKTMLD 601 RR++ P F + LK K D Sbjct: 148 RRMLTPAFHFNILKPYVKIFND 169
>CP311_DROME (Q9VYQ7) Probable cytochrome P450 311a1 (EC 1.14.-.-) (CYPCCCXIA1)| Length = 483 Score = 40.4 bits (93), Expect = 0.004 Identities = 27/95 (28%), Positives = 43/95 (45%), Gaps = 5/95 (5%) Frame = +2 Query: 290 VGDHKYLPRIAPHYL-----KWRAQHGEPFLYWHGPQPRICIFEYEMARQILSTKSGHFV 454 +G+ + + ++ P Y+ + R + G + GPQ + + E RQ L + Sbjct: 38 LGNAQMVGKLRPEYIFLVFTELRDRFGATYRLRLGPQLWVFLHSAEETRQALHDPT--LR 95 Query: 455 KNDAHPTLLALVGKGLGFMEGADWVRHRRIINPVF 559 K D L L+G GL GA W R RR++ P F Sbjct: 96 KADTFMQLEPLIGNGLLISHGAHWTRQRRLLTPAF 130
>CP3AP_MOUSE (O09158) Cytochrome P450 3A25 (EC 1.14.14.1) (CYPIIIA25)| Length = 503 Score = 40.4 bits (93), Expect = 0.004 Identities = 22/86 (25%), Positives = 42/86 (48%) Frame = +2 Query: 347 QHGEPFLYWHGPQPRICIFEYEMARQILSTKSGHFVKNDAHPTLLALVGKGLGFMEGADW 526 ++G+ + ++ GPQP + I + E+ + +L + N + + K + E +W Sbjct: 67 KYGKIWGFYEGPQPILAIMDPEIIKIVLVKECYSVFTNRRFFGPVGFMKKAITISEDEEW 126 Query: 527 VRHRRIINPVFTIDKLKMMTKTMLDF 604 R R +++P FT KLK M M + Sbjct: 127 KRLRTLLSPTFTSGKLKEMFPIMRQY 152
>CP4AA_RAT (P08516) Cytochrome P450 4A10 (EC 1.14.15.3) (CYPIVA10) (Lauric| acid omega-hydroxylase) (P450-LA-omega 1) (P452) Length = 509 Score = 40.0 bits (92), Expect = 0.005 Identities = 23/81 (28%), Positives = 37/81 (45%) Frame = +2 Query: 359 PFLYWHGPQPRICIFEYEMARQILSTKSGHFVKNDAHPTLLALVGKGLGFMEGADWVRHR 538 P +W G + + +++ + + IL N + L +G GL + G W +HR Sbjct: 86 PRWFW-GSKAYLIVYDPDYMKVILGRSDPK--ANGVYRLLAPWIGYGLLLLNGQPWFQHR 142 Query: 539 RIINPVFTIDKLKMMTKTMLD 601 R++ P F D LK K M D Sbjct: 143 RMLTPAFHYDILKPYVKNMAD 163
>CP17A_HORSE (Q95328) Cytochrome P450 17A1 (EC 1.14.99.9) (CYPXVII) (P450-C17)| (P450c17) (Steroid 17-alpha-hydroxylase/17,20 lyase) Length = 508 Score = 39.7 bits (91), Expect = 0.007 Identities = 28/100 (28%), Positives = 48/100 (48%), Gaps = 6/100 (6%) Frame = +2 Query: 290 VGDHKYLPRIA-PH--YLKWRAQHGEPFLYWHGPQPRICIFEYEMARQILSTKSGHFVKN 460 VG +LPR PH + K + ++G + G + + + Y++A+++L K F Sbjct: 37 VGSLPFLPRHGHPHVNFFKLQKKYGPIYSLRMGTKTTVMVGHYQLAKEVLIKKGKEFSGR 96 Query: 461 DAHPTLLALVG--KGLGFME-GADWVRHRRIINPVFTIDK 571 TL L KG+ F + GA W HR+++ F + K Sbjct: 97 PQVATLNILSDNQKGVAFADHGAPWQLHRKLVRAAFALFK 136
>CP3AF_CAVPO (Q64406) Cytochrome P450 3A15 (EC 1.14.14.1) (CYPIIIA15)| Length = 503 Score = 39.7 bits (91), Expect = 0.007 Identities = 23/84 (27%), Positives = 40/84 (47%) Frame = +2 Query: 332 LKWRAQHGEPFLYWHGPQPRICIFEYEMARQILSTKSGHFVKNDAHPTLLALVGKGLGFM 511 ++ R ++G + + GPQP + I E +M + +L + N + + K + Sbjct: 62 IECRKKYGNMWGLYDGPQPVLAITEPDMIKAVLVKECYSVFTNRRSLVPVGFMKKSVSLS 121 Query: 512 EGADWVRHRRIINPVFTIDKLKMM 583 E +W R R ++P FT KLK M Sbjct: 122 EDEEWKRIRTQLSPNFTSGKLKEM 145
>CP3AE_CAVPO (Q64417) Cytochrome P450 3A14 (EC 1.14.14.1) (CYPIIIA14)| Length = 503 Score = 39.7 bits (91), Expect = 0.007 Identities = 23/84 (27%), Positives = 40/84 (47%) Frame = +2 Query: 332 LKWRAQHGEPFLYWHGPQPRICIFEYEMARQILSTKSGHFVKNDAHPTLLALVGKGLGFM 511 ++ R ++G + + GPQP + I E +M + +L + N + + K + Sbjct: 62 IECRKKYGNMWGLYDGPQPVLAITEPDMIKAVLVKECYSVFTNRRSLVPVGFMKKAVSLS 121 Query: 512 EGADWVRHRRIINPVFTIDKLKMM 583 E +W R R ++P FT KLK M Sbjct: 122 EDEEWKRIRTQLSPNFTSGKLKEM 145
>CP4A4_RABIT (P10611) Cytochrome P450 4A4 precursor (EC 1.14.14.1) (CYPIVA4)| (Prostaglandin omega-hydroxylase) (P450-P-2) Length = 510 Score = 39.7 bits (91), Expect = 0.007 Identities = 23/90 (25%), Positives = 42/90 (46%), Gaps = 1/90 (1%) Frame = +2 Query: 335 KWRAQHGEPFLYW-HGPQPRICIFEYEMARQILSTKSGHFVKNDAHPTLLALVGKGLGFM 511 KW + +W G + R+ +++ + + IL +N + + +G GL + Sbjct: 77 KWVEKFPGACPWWLSGNKARLLVYDPDYLKVILGRSDPKAPRN--YKLMTPWIGYGLLLL 134 Query: 512 EGADWVRHRRIINPVFTIDKLKMMTKTMLD 601 +G W +HRR++ P F D LK M+D Sbjct: 135 DGQTWFQHRRMLTPAFHYDILKPYVGLMVD 164
>C97B2_SOYBN (O48921) Cytochrome P450 97B2 (EC 1.14.-.-)| Length = 576 Score = 39.3 bits (90), Expect = 0.009 Identities = 24/84 (28%), Positives = 39/84 (46%) Frame = +2 Query: 338 WRAQHGEPFLYWHGPQPRICIFEYEMARQILSTKSGHFVKNDAHPTLLALVGKGLGFMEG 517 W +HG + GP+ + + + +AR IL + + K L ++GKGL + Sbjct: 101 WFLEHGAVYKLAFGPKAFVVVSDPIVARHILRENAFSYDKGVLADILEPIMGKGLIPADL 160 Query: 518 ADWVRHRRIINPVFTIDKLKMMTK 589 W + RR+I P F L+ M K Sbjct: 161 DTWKQRRRVIAPAFHNSYLEAMVK 184
>CP343_HUMAN (Q9HB55) Cytochrome P450 3A43 (EC 1.14.14.1)| Length = 503 Score = 39.3 bits (90), Expect = 0.009 Identities = 21/79 (26%), Positives = 37/79 (46%) Frame = +2 Query: 347 QHGEPFLYWHGPQPRICIFEYEMARQILSTKSGHFVKNDAHPTLLALVGKGLGFMEGADW 526 ++GE + + G QP + I + +M + +L + N + + L F E +W Sbjct: 67 KYGEMWGLYEGQQPMLVIMDPDMIKTVLVKECYSVFTNQMPLGPMGFLKSALSFAEDEEW 126 Query: 527 VRHRRIINPVFTIDKLKMM 583 R R +++P FT K K M Sbjct: 127 KRIRTLLSPAFTSVKFKEM 145
>CP4Z1_HUMAN (Q86W10) Cytochrome P450 4Z1 (EC 1.14.14.1) (CYPIVZ1)| Length = 505 Score = 38.9 bits (89), Expect = 0.012 Identities = 17/44 (38%), Positives = 27/44 (61%) Frame = +2 Query: 464 AHPTLLALVGKGLGFMEGADWVRHRRIINPVFTIDKLKMMTKTM 595 +H L + VG+GL ++G+ W +HR+I+ P F I LK+ M Sbjct: 113 SHKILESWVGRGLVTLDGSKWKKHRQIVKPGFNISILKIFITMM 156
>CP4B1_HUMAN (P13584) Cytochrome P450 4B1 (EC 1.14.14.1) (CYPIVB1) (P450-HP)| Length = 511 Score = 38.5 bits (88), Expect = 0.015 Identities = 20/60 (33%), Positives = 33/60 (55%) Frame = +2 Query: 398 IFEYEMARQILSTKSGHFVKNDAHPTLLALVGKGLGFMEGADWVRHRRIINPVFTIDKLK 577 I+E + A+ + S G D + L +G+GL +EG W++HR+++ P F D LK Sbjct: 94 IYEPDYAKAVYSR--GDPKAPDVYDFFLQWIGRGLLVLEGPKWLQHRKLLTPGFHYDVLK 151
>CP313_DROME (Q9VHP4) Probable cytochrome P450 313b1 (EC 1.14.-.-)| (CYPCCCXIIIB1) Length = 502 Score = 38.1 bits (87), Expect = 0.020 Identities = 24/72 (33%), Positives = 34/72 (47%), Gaps = 1/72 (1%) Frame = +2 Query: 347 QHGEPFLYWHGPQPRICIFEYEMARQILSTKSGHFV-KNDAHPTLLALVGKGLGFMEGAD 523 Q PF+ W G + I + QIL+ S H K D + + + +G GL Sbjct: 63 QFKAPFISWMGTSCFLYINDPHSVEQILN--STHCTNKGDFYRFMSSAIGDGLFTSSSPR 120 Query: 524 WVRHRRIINPVF 559 W +HRR+INP F Sbjct: 121 WHKHRRLINPAF 132
>CP4B1_RAT (P15129) Cytochrome P450 4B1 (EC 1.14.14.1) (CYPIVB1) (P450-isozyme| 5) (P450 L-2) Length = 510 Score = 38.1 bits (87), Expect = 0.020 Identities = 24/83 (28%), Positives = 37/83 (44%), Gaps = 1/83 (1%) Frame = +2 Query: 332 LKWRAQHGEPFLYWHGPQPRIC-IFEYEMARQILSTKSGHFVKNDAHPTLLALVGKGLGF 508 + W Q W G I+E + A+ + S G D + L +GKGL Sbjct: 70 VSWAQQFPHAHPLWFGQFVGFLNIYEPDYAKAVYSR--GDPKAADVYDFFLQWIGKGLLV 127 Query: 509 MEGADWVRHRRIINPVFTIDKLK 577 ++G W +HR+++ P F D LK Sbjct: 128 LDGPKWFQHRKLLTPGFHYDVLK 150
>CP4E2_DROME (Q27606) Cytochrome P450 4e2 (EC 1.14.-.-) (CYPIVE2)| Length = 526 Score = 38.1 bits (87), Expect = 0.020 Identities = 23/87 (26%), Positives = 43/87 (49%), Gaps = 1/87 (1%) Frame = +2 Query: 338 WRAQHGEP-FLYWHGPQPRICIFEYEMARQILSTKSGHFVKNDAHPTLLALVGKGLGFME 514 W Q+G+ F++W G + + + ILS+++ K+D + +G GL Sbjct: 62 WWHQYGKDNFVFWIGTYSNVLVTSSKYLEFILSSQT-LITKSDIYQLTHPWLGLGLLTST 120 Query: 515 GADWVRHRRIINPVFTIDKLKMMTKTM 595 G+ W +HR++I P F + L+ + M Sbjct: 121 GSKWHKHRKMITPAFHFNILQDFHEVM 147
>CP3A6_RABIT (P11707) Cytochrome P450 3A6 (EC 1.14.14.1) (CYPIIIA6) (P450-3C)| Length = 501 Score = 38.1 bits (87), Expect = 0.020 Identities = 22/84 (26%), Positives = 41/84 (48%) Frame = +2 Query: 332 LKWRAQHGEPFLYWHGPQPRICIFEYEMARQILSTKSGHFVKNDAHPTLLALVGKGLGFM 511 ++ R ++G+ + + G QP + I + +M + +L + N + + K + Sbjct: 60 IECRKKYGKMWGLFDGRQPLMVITDPDMIKTVLVKECYSVFTNRRSFGPVGFMKKAVSIS 119 Query: 512 EGADWVRHRRIINPVFTIDKLKMM 583 E DW R R +++P FT KLK M Sbjct: 120 EDEDWKRVRTLLSPTFTSGKLKEM 143
>C97B1_PEA (Q43078) Cytochrome P450 97B1 (EC 1.14.-.-) (P450 97A2)| Length = 552 Score = 38.1 bits (87), Expect = 0.020 Identities = 23/84 (27%), Positives = 39/84 (46%) Frame = +2 Query: 338 WRAQHGEPFLYWHGPQPRICIFEYEMARQILSTKSGHFVKNDAHPTLLALVGKGLGFMEG 517 W +HG + GP+ + + + +AR IL + + K L ++GKGL + Sbjct: 110 WFLEHGSVYKLAFGPKAFVVVSDPIVARHILRENAFSYDKGVLADILEPIMGKGLIPADL 169 Query: 518 ADWVRHRRIINPVFTIDKLKMMTK 589 W + RR+I P F L+ M + Sbjct: 170 ETWKQRRRVIAPGFHTSYLEAMVQ 193
>CP4F4_RAT (P51869) Cytochrome P450 4F4 (EC 1.14.14.1) (CYPIVF4)| Length = 522 Score = 38.1 bits (87), Expect = 0.020 Identities = 26/88 (29%), Positives = 41/88 (46%), Gaps = 2/88 (2%) Frame = +2 Query: 344 AQHGEPFLYWHGP-QPRICIFEYEMARQILSTKSGHFVKNDAHPTLLA-LVGKGLGFMEG 517 A + + F+ W GP P I + ++ R +LS + +K + L +G GL +G Sbjct: 82 ATYPQGFMTWLGPILPIITLCHPDVIRSVLSASASVALKEVIFYSFLKPWLGDGLLLSDG 141 Query: 518 ADWVRHRRIINPVFTIDKLKMMTKTMLD 601 W HRR++ P F + LK K D Sbjct: 142 DKWSCHRRMLTPAFHFNILKPYVKIFND 169
>CP4AE_RAT (P20817) Cytochrome P450 4A14 precursor (EC 1.14.15.3) (CYPIVA14)| (Lauric acid omega-hydroxylase) (P450-LA-omega 3) Length = 507 Score = 37.7 bits (86), Expect = 0.026 Identities = 25/102 (24%), Positives = 41/102 (40%), Gaps = 1/102 (0%) Frame = +2 Query: 299 HKYLPRIAPHYLKWRAQHGEPFLYW-HGPQPRICIFEYEMARQILSTKSGHFVKNDAHPT 475 H R L W + L W G + R+ +++ + + +L + + Sbjct: 62 HDLKDREFQQVLTWVEKFPGACLQWLSGSKTRVLLYDPDYVKVVLGRSDPK--ASGIYQF 119 Query: 476 LLALVGKGLGFMEGADWVRHRRIINPVFTIDKLKMMTKTMLD 601 L +G GL + G W +HRR++ P F LK K M D Sbjct: 120 LAPWIGYGLLLLNGKKWFQHRRMLTPAFHYGILKPYVKIMAD 161
>CP4B1_RABIT (P15128) Cytochrome P450 4B1 (EC 1.14.14.1) (CYPIVB1) (P450-isozyme| 5) Length = 506 Score = 37.7 bits (86), Expect = 0.026 Identities = 20/60 (33%), Positives = 32/60 (53%) Frame = +2 Query: 398 IFEYEMARQILSTKSGHFVKNDAHPTLLALVGKGLGFMEGADWVRHRRIINPVFTIDKLK 577 I+E + A+ + S G D + L +GKGL ++G W +HR+++ P F D LK Sbjct: 89 IYEPDYAKAVYSR--GDPKAPDVYDFFLQWIGKGLLVLDGPKWFQHRKLLTPGFHYDVLK 146
>CP4F8_HUMAN (P98187) Cytochrome P450 4F8 (EC 1.14.14.1) (CYPIVF8)| Length = 520 Score = 37.7 bits (86), Expect = 0.026 Identities = 25/84 (29%), Positives = 40/84 (47%), Gaps = 2/84 (2%) Frame = +2 Query: 344 AQHGEPFLYWHGP-QPRICIFEYEMARQILSTKSGHFVKNDA-HPTLLALVGKGLGFMEG 517 A + + F+ W GP P I + ++ R +++T K+ + TL +G GL G Sbjct: 82 ATYPQGFVRWLGPITPIINLCHPDIVRSVINTSDAITDKDIVFYKTLKPWLGDGLLLSVG 141 Query: 518 ADWVRHRRIINPVFTIDKLKMMTK 589 W HRR++ P F + LK K Sbjct: 142 DKWRHHRRLLTPAFHFNILKPYIK 165
>CP132_DROME (Q9VGB4) Probable cytochrome P450 313a2 (EC 1.14.-.-)| (CYPCCCXIIIA2) Length = 493 Score = 37.4 bits (85), Expect = 0.034 Identities = 21/74 (28%), Positives = 40/74 (54%), Gaps = 3/74 (4%) Frame = +2 Query: 347 QHGEPFLYWHGPQPRICIFEYEMARQILSTKSGHFVKNDAHPTLLAL---VGKGLGFMEG 517 +HG ++ W G P + + ++A ++L++ F N + T AL +G GL ++G Sbjct: 64 KHGSTYMAWIGTTPIVITRDPKIAEKVLTSP---FCINRSSQTTNALALSMGYGLLTLQG 120 Query: 518 ADWVRHRRIINPVF 559 + W+ R+ +NP F Sbjct: 121 SKWMARRKHMNPAF 134
>CP3A2_RAT (P05183) Cytochrome P450 3A2 (EC 1.14.14.1) (CYPIIIA2) (P450-PCN2)| (P450/6-beta-A) (Testosterone 6-beta-hydroxylase) Length = 504 Score = 37.4 bits (85), Expect = 0.034 Identities = 19/79 (24%), Positives = 39/79 (49%) Frame = +2 Query: 347 QHGEPFLYWHGPQPRICIFEYEMARQILSTKSGHFVKNDAHPTLLALVGKGLGFMEGADW 526 ++G+ + + G P I + EM + +L + N + ++GK + + +W Sbjct: 67 KYGKIWGLFDGQTPVFAIMDTEMIKNVLVKECFSVFTNRRDFGPVGIMGKAVSVAKDEEW 126 Query: 527 VRHRRIINPVFTIDKLKMM 583 R+R +++P FT +LK M Sbjct: 127 KRYRALLSPTFTSGRLKEM 145
>CP3A1_RAT (P04800) Cytochrome P450 3A1 (EC 1.14.14.1) (CYPIIIA1) (P450-PCN1)| Length = 504 Score = 37.4 bits (85), Expect = 0.034 Identities = 19/79 (24%), Positives = 39/79 (49%) Frame = +2 Query: 347 QHGEPFLYWHGPQPRICIFEYEMARQILSTKSGHFVKNDAHPTLLALVGKGLGFMEGADW 526 ++G+ + + G P I + EM + +L + N + ++GK + + +W Sbjct: 67 KYGKIWGLFDGQMPLFAITDTEMIKNVLVKECFSVFTNRRDFGPVGIMGKAVSVAKDEEW 126 Query: 527 VRHRRIINPVFTIDKLKMM 583 R+R +++P FT +LK M Sbjct: 127 KRYRALLSPTFTSGRLKEM 145
>CP341_MOUSE (Q9JMA7) Cytochrome P450 3A41 (EC 1.14.14.1)| Length = 504 Score = 37.4 bits (85), Expect = 0.034 Identities = 19/79 (24%), Positives = 38/79 (48%) Frame = +2 Query: 347 QHGEPFLYWHGPQPRICIFEYEMARQILSTKSGHFVKNDAHPTLLALVGKGLGFMEGADW 526 ++G+ + + G P I + EM + +L + N + ++ K + + +W Sbjct: 67 KYGKTWGLFDGQMPLFVITDPEMIKNVLVKECFSVFTNRREFGPVGIMSKAISISKDEEW 126 Query: 527 VRHRRIINPVFTIDKLKMM 583 R+R +++P FT KLK M Sbjct: 127 KRYRALLSPTFTSGKLKEM 145
>CP4A5_RABIT (P14579) Cytochrome P450 4A5 precursor (EC 1.14.15.3) (CYPIVA5)| (Lauric acid omega-hydroxylase) Length = 511 Score = 37.4 bits (85), Expect = 0.034 Identities = 23/91 (25%), Positives = 41/91 (45%), Gaps = 1/91 (1%) Frame = +2 Query: 332 LKWRAQHGEPFLYW-HGPQPRICIFEYEMARQILSTKSGHFVKNDAHPTLLALVGKGLGF 508 LKW + +W G + R+ +++ + + IL ++ + +G GL Sbjct: 76 LKWVEKFPRACPHWIGGNKVRVQLYDPDYMKVILGRSDPK--SRGSYTFVAPWIGYGLLL 133 Query: 509 MEGADWVRHRRIINPVFTIDKLKMMTKTMLD 601 + G W +HRR++ P F D LK M+D Sbjct: 134 LNGQPWFQHRRMLTPAFHYDILKPYVGLMVD 164
>CP17A_SHEEP (Q29497) Cytochrome P450 17A1 (EC 1.14.99.9) (CYPXVII) (P450-C17)| (P450c17) (Steroid 17-alpha-hydroxylase/17,20 lyase) Length = 509 Score = 37.4 bits (85), Expect = 0.034 Identities = 27/100 (27%), Positives = 48/100 (48%), Gaps = 6/100 (6%) Frame = +2 Query: 290 VGDHKYLPRIAP---HYLKWRAQHGEPFLYWHGPQPRICIFEYEMARQILSTKSGHFVKN 460 VG +LPR ++ K + ++G + + G + + I +++AR++L K F Sbjct: 37 VGSLPFLPRRGQQHENFFKLQEKYGPIYSFRLGSKTTVMIGHHQLAREVLLKKGKEFSGR 96 Query: 461 DAHPTLLALVG--KGLGFME-GADWVRHRRIINPVFTIDK 571 TL L KG+ F + GA W HR+++ F + K Sbjct: 97 PKVATLDILSDNQKGIAFADHGAHWQLHRKLVLNAFALFK 136
>CP4AC_RAT (P24464) Cytochrome P450 4A12 (EC 1.14.14.1) (CYPIVA12) (CYPIVA8)| (P450-KP1) (P450-PP1) Length = 508 Score = 37.0 bits (84), Expect = 0.044 Identities = 24/78 (30%), Positives = 36/78 (46%), Gaps = 3/78 (3%) Frame = +2 Query: 377 GPQPRICIFEYEMARQILST---KSGHFVKNDAHPTLLALVGKGLGFMEGADWVRHRRII 547 G RI +++ + + IL KS H ++ L +G GL + G W +HRR++ Sbjct: 90 GSNVRIQVYDPDYMKLILGRSDPKSHH-----SYRFLAPWIGYGLLLLNGQTWFQHRRML 144 Query: 548 NPVFTIDKLKMMTKTMLD 601 P F D LK M D Sbjct: 145 TPAFHYDTLKPYVGIMAD 162
>CP4AE_MOUSE (O35728) Cytochrome P450 4A14 precursor (EC 1.14.15.3) (CYPIVA14)| (Lauric acid omega-hydroxylase 3) (P450-LA-omega 3) Length = 507 Score = 37.0 bits (84), Expect = 0.044 Identities = 16/38 (42%), Positives = 21/38 (55%) Frame = +2 Query: 488 VGKGLGFMEGADWVRHRRIINPVFTIDKLKMMTKTMLD 601 +G GL + G W +HRR++ P F D LK K M D Sbjct: 124 IGYGLLLLNGKKWFQHRRMLTPAFHYDILKPYVKIMAD 161
>CP4E1_DROME (Q9V4T5) Probable cytochrome P450 4e1 (EC 1.14.-.-) (CYPIVE1)| Length = 531 Score = 37.0 bits (84), Expect = 0.044 Identities = 25/94 (26%), Positives = 44/94 (46%), Gaps = 1/94 (1%) Frame = +2 Query: 317 IAPHYLKWRAQHGEP-FLYWHGPQPRICIFEYEMARQILSTKSGHFVKNDAHPTLLALVG 493 I + W ++G+ F YW G I + + ILS+++ K+D + +G Sbjct: 55 ILNRFFGWWHEYGKDNFRYWIGYYSNIMVTNPKYMEFILSSQT-LISKSDVYDLTHPWLG 113 Query: 494 KGLGFMEGADWVRHRRIINPVFTIDKLKMMTKTM 595 GL G+ W +HR++I P F + L+ + M Sbjct: 114 LGLLTSTGSKWHKHRKMITPAFHFNILQDFHEVM 147
>CP3AC_CANFA (P24463) Cytochrome P450 3A12 (EC 1.14.14.1) (CYPIIIA12)| (P450-PBD-1) Length = 503 Score = 37.0 bits (84), Expect = 0.044 Identities = 20/84 (23%), Positives = 40/84 (47%) Frame = +2 Query: 332 LKWRAQHGEPFLYWHGPQPRICIFEYEMARQILSTKSGHFVKNDAHPTLLALVGKGLGFM 511 +K +++G + ++ G QP + I + +M + +L + N + + + Sbjct: 62 MKCFSKYGRMWGFYDGRQPVLAITDPDMIKTVLVKECYSVFTNRRTLGPVGFMKSAISLS 121 Query: 512 EGADWVRHRRIINPVFTIDKLKMM 583 E +W R R +++P FT KLK M Sbjct: 122 EDEEWKRMRTLLSPTFTTGKLKEM 145
>CP4A7_RABIT (P14581) Cytochrome P450 4A7 precursor (EC 1.14.15.3) (CYPIVA7)| (Lauric acid omega-hydroxylase) (P450-KA-2) Length = 511 Score = 37.0 bits (84), Expect = 0.044 Identities = 16/38 (42%), Positives = 22/38 (57%) Frame = +2 Query: 488 VGKGLGFMEGADWVRHRRIINPVFTIDKLKMMTKTMLD 601 +G GL +EG W +HRR++ P F D LK M+D Sbjct: 127 IGYGLLLLEGQTWFQHRRMLTPAFHYDILKPYVGLMVD 164
>CP17A_CAPHI (Q9N0U7) Cytochrome P450 17A1 (EC 1.14.99.9) (CYPXVII) (P450-C17)| (P450c17) (Steroid 17-alpha-hydroxylase/17,20 lyase) Length = 509 Score = 37.0 bits (84), Expect = 0.044 Identities = 27/100 (27%), Positives = 48/100 (48%), Gaps = 6/100 (6%) Frame = +2 Query: 290 VGDHKYLPRIAP---HYLKWRAQHGEPFLYWHGPQPRICIFEYEMARQILSTKSGHFVKN 460 VG +LPR ++ K + ++G + + G + + I +++AR++L K F Sbjct: 37 VGSLLFLPRRGQQHENFFKLQEKYGPIYSFRLGSKTTVMIGHHQLAREVLLKKGKEFSGR 96 Query: 461 DAHPTLLALVG--KGLGFME-GADWVRHRRIINPVFTIDK 571 TL L KG+ F + GA W HR+++ F + K Sbjct: 97 PKVATLDILSDNQKGIAFADHGAHWQLHRKLVLNAFALFK 136
>CP3AT_PIG (P79401) Cytochrome P450 3A29 (EC 1.14.14.1) (CYPIIIA29)| Length = 503 Score = 36.6 bits (83), Expect = 0.058 Identities = 21/79 (26%), Positives = 36/79 (45%) Frame = +2 Query: 347 QHGEPFLYWHGPQPRICIFEYEMARQILSTKSGHFVKNDAHPTLLALVGKGLGFMEGADW 526 Q+G+ + + G QP + + + M + +L + N L + L E +W Sbjct: 67 QYGKMWGVYDGRQPLLAVTDPNMIKSVLVKECYSVFTNRRSFGPLGAMRNALSLAEDEEW 126 Query: 527 VRHRRIINPVFTIDKLKMM 583 R R +++P FT KLK M Sbjct: 127 KRIRTLLSPTFTSGKLKEM 145
>C97B3_ARATH (O23365) Cytochrome P450 97B3 (EC 1.14.-.-)| Length = 580 Score = 36.6 bits (83), Expect = 0.058 Identities = 25/88 (28%), Positives = 38/88 (43%) Frame = +2 Query: 338 WRAQHGEPFLYWHGPQPRICIFEYEMARQILSTKSGHFVKNDAHPTLLALVGKGLGFMEG 517 W +HG + GP+ + I + +AR +L + + K L ++GKGL + Sbjct: 106 WFLEHGGIYKLAFGPKAFVVISDPIIARHVLRENAFSYDKGVLAEILEPIMGKGLIPADL 165 Query: 518 ADWVRHRRIINPVFTIDKLKMMTKTMLD 601 W RR I P F L+ M K D Sbjct: 166 DTWKLRRRAITPAFHKLYLEAMVKVFSD 193
>CP4B1_MOUSE (Q64462) Cytochrome P450 4B1 (EC 1.14.14.1) (CYPIVB1)| Length = 511 Score = 36.2 bits (82), Expect = 0.076 Identities = 19/48 (39%), Positives = 26/48 (54%), Gaps = 7/48 (14%) Frame = +2 Query: 479 LALVGKGLGFMEGADWVRHRRIINPVFTIDKLK-------MMTKTMLD 601 L +GKGL +EG W +HR+++ P F D LK T+ MLD Sbjct: 119 LQWIGKGLLVLEGPKWFQHRKLLTPGFHYDVLKPYVAIFAESTRVMLD 166
>CP131_DROME (Q9VFJ0) Probable cytochrome P450 313a1 (EC 1.14.-.-)| (CYPCCCXIIIA1) Length = 492 Score = 36.2 bits (82), Expect = 0.076 Identities = 21/80 (26%), Positives = 34/80 (42%) Frame = +2 Query: 335 KWRAQHGEPFLYWHGPQPRICIFEYEMARQILSTKSGHFVKNDAHPTLLALVGKGLGFME 514 K+ ++G L W GP P I + ++ I S+ H + + +G GL + Sbjct: 60 KYLNKYGSTILTWMGPVPFIVTRDPKVVEDIFSSPDCHNKSQHIVNAITSCMGNGLLGKQ 119 Query: 515 GADWVRHRRIINPVFTIDKL 574 W+ R+ NP F D L Sbjct: 120 DPHWLDRRKHFNPSFKQDLL 139
>CP4F2_HUMAN (P78329) Cytochrome P450 4F2 (EC 1.14.13.30) (CYPIVF2)| (Leukotriene-B(4) omega-hydroxylase) (Leukotriene-B(4) 20-monooxygenase) (Cytochrome P450-LTB-omega) Length = 520 Score = 36.2 bits (82), Expect = 0.076 Identities = 23/84 (27%), Positives = 39/84 (46%), Gaps = 2/84 (2%) Frame = +2 Query: 344 AQHGEPFLYWHGP-QPRICIFEYEMARQILSTKSGHFVKNDAHPTLLA-LVGKGLGFMEG 517 A + + F W GP P + + ++ R +++ + K+ + L +G GL G Sbjct: 82 ATYPQGFKVWMGPISPLLSLCHPDIIRSVINASAAIAPKDKFFYSFLEPWLGDGLLLSAG 141 Query: 518 ADWVRHRRIINPVFTIDKLKMMTK 589 W RHRR++ P F + LK K Sbjct: 142 DKWSRHRRMLTPAFHFNILKPYMK 165
>CP4AB_HUMAN (Q02928) Cytochrome P450 4A11 precursor (EC 1.14.15.3) (CYPIVA11)| (Fatty acid omega-hydroxylase) (P-450 HK omega) (Lauric acid omega-hydroxylase) (CYP4AII) (P450-HL-omega) Length = 519 Score = 35.8 bits (81), Expect = 0.099 Identities = 22/81 (27%), Positives = 37/81 (45%) Frame = +2 Query: 359 PFLYWHGPQPRICIFEYEMARQILSTKSGHFVKNDAHPTLLALVGKGLGFMEGADWVRHR 538 P W G + R+ +++ + + IL + ++ L +G GL + G W +HR Sbjct: 87 PHWLWGG-KVRVQLYDPDYMKVILGRSDPK--SHGSYRFLAPWIGYGLLLLNGQTWFQHR 143 Query: 539 RIINPVFTIDKLKMMTKTMLD 601 R++ P F D LK M D Sbjct: 144 RMLTPAFHYDILKPYVGLMAD 164
>CP3A4_HUMAN (P08684) Cytochrome P450 3A4 (EC 1.14.13.67) (Quinine| 3-monooxygenase) (CYPIIIA4) (Nifedipine oxidase) (Taurochenodeoxycholate 6-alpha-hydroxylase) (EC 1.14.13.97) (NF-25) (P450-PCN1) Length = 502 Score = 35.8 bits (81), Expect = 0.099 Identities = 19/86 (22%), Positives = 40/86 (46%) Frame = +2 Query: 347 QHGEPFLYWHGPQPRICIFEYEMARQILSTKSGHFVKNDAHPTLLALVGKGLGFMEGADW 526 ++G+ + ++ G QP + I + +M + +L + N + + + E +W Sbjct: 66 KYGKVWGFYDGQQPVLAITDPDMIKTVLVKECYSVFTNRRPFGPVGFMKSAISIAEDEEW 125 Query: 527 VRHRRIINPVFTIDKLKMMTKTMLDF 604 R R +++P FT KLK M + + Sbjct: 126 KRLRSLLSPTFTSGKLKEMVPIIAQY 151
>C4D14_DROME (O46051) Probable cytochrome P450 4d14 (EC 1.14.-.-) (CYPIVD14)| Length = 507 Score = 35.8 bits (81), Expect = 0.099 Identities = 37/147 (25%), Positives = 59/147 (40%), Gaps = 5/147 (3%) Frame = +2 Query: 134 WDYAVVRLVWRPYAMSKWFREQGIHGPSYRFLKG-----CNEDVRSIKEETDRLVLDVGD 298 WDY R +K + E GI GP L G NE ++I + RL+ + G Sbjct: 16 WDYM------RKRRHNKMYAEAGIRGPKSYPLVGNAPLLINESPKTIFDMQFRLIAEFGK 69 Query: 299 HKYLPRIAPHYLKWRAQHGEPFLYWHGPQPRICIFEYEMARQILSTKSGHFVKNDAHPTL 478 + +K + F+ + +M I+S++ KN+ + L Sbjct: 70 N----------IKTQMLGESGFM----------TADSKMIEAIMSSQQT-IQKNNLYSLL 108 Query: 479 LALVGKGLGFMEGADWVRHRRIINPVF 559 + +G GL +G W R R+II P F Sbjct: 109 VNWLGDGLLISQGKKWFRRRKIITPAF 135
>CP4D8_DROME (Q9VS79) Cytochrome P450 4d8 (EC 1.14.-.-) (CYPIVD8)| Length = 463 Score = 35.8 bits (81), Expect = 0.099 Identities = 24/87 (27%), Positives = 40/87 (45%), Gaps = 8/87 (9%) Frame = +2 Query: 353 GEPFLYWHGPQPRICIF--------EYEMARQILSTKSGHFVKNDAHPTLLALVGKGLGF 508 G ++ G R+ IF + E+ Q+LS++ H VK+ + L +G GL Sbjct: 16 GREYVLKFGHLQRVWIFNRLLIMSGDAELNEQLLSSQE-HLVKHPVYKVLGQWLGNGLLL 74 Query: 509 MEGADWVRHRRIINPVFTIDKLKMMTK 589 +G W + R+II P F L+ + Sbjct: 75 SDGKVWHQRRKIITPTFHFSILEQFVE 101
>CP17A_PAPHU (Q9GLD2) Cytochrome P450 17A1 (EC 1.14.99.9) (CYPXVII) (P450-C17)| (P450c17) (Steroid 17-alpha-hydroxylase/17,20 lyase) Length = 508 Score = 35.4 bits (80), Expect = 0.13 Identities = 26/100 (26%), Positives = 47/100 (47%), Gaps = 6/100 (6%) Frame = +2 Query: 290 VGDHKYLPR---IAPHYLKWRAQHGEPFLYWHGPQPRICIFEYEMARQILSTKSGHFVKN 460 VG +LPR + ++ K + ++G + G + + + +++A+++L K F Sbjct: 37 VGSLPFLPRHGHMHNNFFKLQKKYGPIYSVRMGTKTTVIVGHHQLAKEVLIKKGKDFSGR 96 Query: 461 DAHPTLLALVG--KGLGFME-GADWVRHRRIINPVFTIDK 571 TL L KG+ F + GA W HRR+ F + K Sbjct: 97 PQVTTLDILSNNRKGIAFADYGAHWQLHRRLAMATFALFK 136
>CP17A_PAPCY (Q8HYN0) Cytochrome P450 17A1 (EC 1.14.99.9) (CYPXVII) (P450-C17)| (P450c17) (Steroid 17-alpha-hydroxylase/17,20 lyase) Length = 508 Score = 35.4 bits (80), Expect = 0.13 Identities = 26/100 (26%), Positives = 47/100 (47%), Gaps = 6/100 (6%) Frame = +2 Query: 290 VGDHKYLPR---IAPHYLKWRAQHGEPFLYWHGPQPRICIFEYEMARQILSTKSGHFVKN 460 VG +LPR + ++ K + ++G + G + + + +++A+++L K F Sbjct: 37 VGSLPFLPRHGHMHNNFFKLQKKYGPIYSVRMGTKTTVIVGHHQLAKEVLIKKGKDFSGR 96 Query: 461 DAHPTLLALVG--KGLGFME-GADWVRHRRIINPVFTIDK 571 TL L KG+ F + GA W HRR+ F + K Sbjct: 97 PQVTTLDILSNNRKGIAFADYGAHWQLHRRLAMATFALFK 136
>CP17A_MACMU (Q8HYM9) Cytochrome P450 17A1 (EC 1.14.99.9) (CYPXVII) (P450-C17)| (P450c17) (Steroid 17-alpha-hydroxylase/17,20 lyase) Length = 508 Score = 35.4 bits (80), Expect = 0.13 Identities = 26/100 (26%), Positives = 47/100 (47%), Gaps = 6/100 (6%) Frame = +2 Query: 290 VGDHKYLPR---IAPHYLKWRAQHGEPFLYWHGPQPRICIFEYEMARQILSTKSGHFVKN 460 VG +LPR + ++ K + ++G + G + + + +++A+++L K F Sbjct: 37 VGSLPFLPRHGHMHNNFFKLQKKYGPIYSVRMGTKTTVIVGHHQLAKEVLIKKGKDFSGR 96 Query: 461 DAHPTLLALVG--KGLGFME-GADWVRHRRIINPVFTIDK 571 TL L KG+ F + GA W HRR+ F + K Sbjct: 97 PQVTTLDILSNNRKGIAFADYGAHWQLHRRLAMATFALFK 136
>CP17A_MACFA (Q2XVA1) Cytochrome P450 17A1 (EC 1.14.99.9) (CYPXVII) (P450-C17)| (P450c17) (Steroid 17-alpha-hydroxylase/17,20 lyase) Length = 508 Score = 35.4 bits (80), Expect = 0.13 Identities = 26/100 (26%), Positives = 47/100 (47%), Gaps = 6/100 (6%) Frame = +2 Query: 290 VGDHKYLPR---IAPHYLKWRAQHGEPFLYWHGPQPRICIFEYEMARQILSTKSGHFVKN 460 VG +LPR + ++ K + ++G + G + + + +++A+++L K F Sbjct: 37 VGSLPFLPRHGHMHNNFFKLQKKYGPIYSVRMGTKTTVIVGHHQLAKEVLIKKGKDFSGR 96 Query: 461 DAHPTLLALVG--KGLGFME-GADWVRHRRIINPVFTIDK 571 TL L KG+ F + GA W HRR+ F + K Sbjct: 97 PQVTTLDILSNNRKGIAFADYGAHWQLHRRLAMATFALFK 136
>CP4A6_RABIT (P14580) Cytochrome P450 4A6 precursor (EC 1.14.15.3) (CYPIVA6)| (Lauric acid omega-hydroxylase) (P450-KA-1) Length = 510 Score = 35.4 bits (80), Expect = 0.13 Identities = 24/91 (26%), Positives = 38/91 (41%), Gaps = 1/91 (1%) Frame = +2 Query: 332 LKWRAQHGEPFLYW-HGPQPRICIFEYEMARQILSTKSGHFVKNDAHPTLLALVGKGLGF 508 LKW + W G + + I++ + + IL ++ L +G GL Sbjct: 76 LKWVEKFPSACPRWLWGSRAHLLIYDPDYMKVILGRSDPK--AQGSYRFLAPWIGYGLLL 133 Query: 509 MEGADWVRHRRIINPVFTIDKLKMMTKTMLD 601 + G W +HRR++ P F D LK M D Sbjct: 134 LNGQTWFQHRRMLTPAFHYDILKPYVGLMAD 164
>CP3A3_HUMAN (P05184) Cytochrome P450 3A3 (EC 1.14.14.1) (CYPIIIA3) (HLp)| Length = 503 Score = 35.4 bits (80), Expect = 0.13 Identities = 19/86 (22%), Positives = 40/86 (46%) Frame = +2 Query: 347 QHGEPFLYWHGPQPRICIFEYEMARQILSTKSGHFVKNDAHPTLLALVGKGLGFMEGADW 526 ++G+ + ++ G QP + I + +M + +L + N + + + E +W Sbjct: 66 KYGKVWGFYDGQQPVLAITDPDMIKLVLVKECYSVFTNREPFGPVGFMKSAISIAEDEEW 125 Query: 527 VRHRRIINPVFTIDKLKMMTKTMLDF 604 R R +++P FT KLK M + + Sbjct: 126 KRLRSLLSPTFTSGKLKEMVPIIAQY 151
>C4AA1_DROME (Q9V7G5) Probable cytochrome P450 4aa1 (EC 1.14.-.-) (CYPIVAA1)| Length = 514 Score = 35.4 bits (80), Expect = 0.13 Identities = 23/72 (31%), Positives = 34/72 (47%) Frame = +2 Query: 386 PRICIFEYEMARQILSTKSGHFVKNDAHPTLLALVGKGLGFMEGADWVRHRRIINPVFTI 565 P + E E + ILS+K H K + + +G GL G+ W HRR+I P F Sbjct: 96 PFFAVLEPEDLQVILSSKK-HTNKVFFYRLMHNFLGDGLITSSGSKWSNHRRLIQPAFHH 154 Query: 566 DKLKMMTKTMLD 601 + L+ T +D Sbjct: 155 NLLEKFIDTFVD 166
>CP4S3_DROME (Q9VXY0) Probable cytochrome P450 4s3 (EC 1.14.-.-) (CYPIVS3)| Length = 495 Score = 35.0 bits (79), Expect = 0.17 Identities = 21/73 (28%), Positives = 32/73 (43%) Frame = +2 Query: 341 RAQHGEPFLYWHGPQPRICIFEYEMARQILSTKSGHFVKNDAHPTLLALVGKGLGFMEGA 520 R +HG F W G + + E +Q+L K+ + L +GKGL G Sbjct: 60 REKHGPVFRIWFGKDLMVMFTDPEDIKQLLGNNQ-LLTKSRNYELLEPWLGKGLLTNGGE 118 Query: 521 DWVRHRRIINPVF 559 W R R+++ P F Sbjct: 119 SWHRRRKLLTPGF 131
>C13A6_CAEEL (Q27515) Putative cytochrome P450 CYP13A6 (EC 1.14.-.-)| Length = 518 Score = 35.0 bits (79), Expect = 0.17 Identities = 25/113 (22%), Positives = 49/113 (43%), Gaps = 7/113 (6%) Frame = +2 Query: 278 LVLDVGDHKYLPRIAPHYLKWRAQHGEPFLYWHGPQPRICIFEYEMARQILSTKSGHFVK 457 +++ DH+ P + Y W Q+G + + GPQ + I E EM +I + +F Sbjct: 40 MLIQTIDHENPPFLK--YRDWTKQYGPVYGFTEGPQQTMIISEPEMVNEIFKKQFDNFYG 97 Query: 458 NDAHPTLLALVGK-------GLGFMEGADWVRHRRIINPVFTIDKLKMMTKTM 595 P ++G + +G W R R + +P F+ + L+ + ++ Sbjct: 98 RKLRP----IIGDPEKDKRVNIFSTQGKRWKRLRTLSSPSFSNNSLRKVRNSV 146
>CP3A9_RAT (P51538) Cytochrome P450 3A9 (EC 1.14.14.1) (CYPIIIA9) (P450-OLF3)| (Olfactive) (3AH15) Length = 503 Score = 35.0 bits (79), Expect = 0.17 Identities = 19/79 (24%), Positives = 40/79 (50%) Frame = +2 Query: 347 QHGEPFLYWHGPQPRICIFEYEMARQILSTKSGHFVKNDAHPTLLALVGKGLGFMEGADW 526 ++G+ + + G QP + I + ++ + +L + N + + ++ K + E +W Sbjct: 67 KYGKLWGLYDGRQPVLAITDPDIIKTVLVKECYSTFTNRRNFGPVGILKKAISISEDEEW 126 Query: 527 VRHRRIINPVFTIDKLKMM 583 R R +++P FT KLK M Sbjct: 127 KRIRALLSPTFTSGKLKEM 145
>CP3AV_MESAU (O70537) Cytochrome P450 3A31 (EC 1.14.14.1) (CYPIIIA31) (P450| SH3A-1) Length = 501 Score = 35.0 bits (79), Expect = 0.17 Identities = 18/79 (22%), Positives = 38/79 (48%) Frame = +2 Query: 347 QHGEPFLYWHGPQPRICIFEYEMARQILSTKSGHFVKNDAHPTLLALVGKGLGFMEGADW 526 ++G+ + + G +P + + EM + +L + N + ++ K + + +W Sbjct: 67 KYGKIWGLFEGQRPLFTVTDTEMIKNVLVKECYSIFTNRRDFGPVGIMSKAVSISKDEEW 126 Query: 527 VRHRRIINPVFTIDKLKMM 583 R R +++P FT KLK M Sbjct: 127 KRIRALLSPTFTSGKLKEM 145
>CP3AB_MOUSE (Q64459) Cytochrome P450 3A11 (EC 1.14.14.1) (CYPIIIA11)| (P-450IIIAM1) (P-450UT) Length = 504 Score = 34.7 bits (78), Expect = 0.22 Identities = 17/79 (21%), Positives = 38/79 (48%) Frame = +2 Query: 347 QHGEPFLYWHGPQPRICIFEYEMARQILSTKSGHFVKNDAHPTLLALVGKGLGFMEGADW 526 ++G+ + + G P + + + E + +L + N + ++ K + + +W Sbjct: 67 KYGKTWGLFDGQTPLLAVTDPETIKNVLVKECFSVFTNRRDFGPVGIMSKAISISKDDEW 126 Query: 527 VRHRRIINPVFTIDKLKMM 583 R+R +++P FT KLK M Sbjct: 127 KRYRALLSPTFTSGKLKEM 145
>NOB1_RAT (Q6VEU1) RNA-binding protein NOB1| Length = 410 Score = 34.7 bits (78), Expect = 0.22 Identities = 29/102 (28%), Positives = 45/102 (44%), Gaps = 8/102 (7%) Frame = -1 Query: 322 RDPREVLVVANVQHQTVGLLLDAPHV--LVAAFQE------PVGGSMDPLFSEPLAHGVR 167 ++P +V V +++QH L + H+ A QE P GS + FS + R Sbjct: 105 KEPEKVKVSSSIQHPETPLHISGFHLPSKSKALQETVDHGPPADGSENLEFSSFMFW--R 162 Query: 166 PPYEAHDGVVPQLRAGNREQSNQNEEEHSKEGHGRGQEEDGG 41 P D + QL RE+ + EEE +E ++DGG Sbjct: 163 NPLPNIDHELQQLLIDGREEEEEEEEEEEEEDELEDSDDDGG 204
>CP4C3_DROME (Q9VA27) Cytochrome P450 4c3 (EC 1.14.-.-) (CYPIVC3)| Length = 535 Score = 34.7 bits (78), Expect = 0.22 Identities = 21/64 (32%), Positives = 32/64 (50%), Gaps = 1/64 (1%) Frame = +2 Query: 371 WHGPQPRICIFEYEMARQILSTKSGHFV-KNDAHPTLLALVGKGLGFMEGADWVRHRRII 547 W G PR+ +FE E IL+++ FV K+ + L +G+GL W R+I+ Sbjct: 101 WQGTAPRVLLFEPETVEPILNSQK--FVNKSHDYDYLHPWLGEGLLTSTDRKWHSRRKIL 158 Query: 548 NPVF 559 P F Sbjct: 159 TPAF 162
>CP3AD_MOUSE (Q64464) Cytochrome P450 3A13 (EC 1.14.14.1) (CYPIIIA13)| Length = 503 Score = 34.3 bits (77), Expect = 0.29 Identities = 18/79 (22%), Positives = 39/79 (49%) Frame = +2 Query: 347 QHGEPFLYWHGPQPRICIFEYEMARQILSTKSGHFVKNDAHPTLLALVGKGLGFMEGADW 526 ++G+ + + G QP + I + ++ + +L + N + ++ K + E +W Sbjct: 67 KYGKMWGLYDGRQPVLAITDPDIIKTVLVKECYSTFTNRRRFGPVGILKKAISISENEEW 126 Query: 527 VRHRRIINPVFTIDKLKMM 583 R R +++P FT +LK M Sbjct: 127 KRIRALLSPTFTSGRLKEM 145
>CP3A8_MACFA (P33268) Cytochrome P450 3A8 (EC 1.14.14.1) (CYPIIIA8) (P450-MKNF2)| (P-450-MK2) Length = 503 Score = 34.3 bits (77), Expect = 0.29 Identities = 19/79 (24%), Positives = 37/79 (46%) Frame = +2 Query: 347 QHGEPFLYWHGPQPRICIFEYEMARQILSTKSGHFVKNDAHPTLLALVGKGLGFMEGADW 526 ++G+ + ++ G QP + I + M + +L + N + + + E +W Sbjct: 67 KYGKVWGFYDGRQPVLAITDPNMIKTVLVKECYSVFTNRRPFGPVGFMKNAISIAEDEEW 126 Query: 527 VRHRRIINPVFTIDKLKMM 583 R R +++P FT KLK M Sbjct: 127 KRIRSLLSPTFTSGKLKEM 145
>CP4FC_HUMAN (Q9HCS2) Cytochrome P450 4F12 (EC 1.14.14.1) (CYPIVF12)| Length = 524 Score = 34.3 bits (77), Expect = 0.29 Identities = 23/80 (28%), Positives = 37/80 (46%), Gaps = 2/80 (2%) Frame = +2 Query: 344 AQHGEPFLYWHGPQ-PRICIFEYEMARQILSTKSGHFVKNDAHPTLLA-LVGKGLGFMEG 517 A + + F W GP P I + + R I + + K++ L +G+G+ G Sbjct: 82 ATYSQGFTVWLGPIIPFIVLCHPDTIRSITNASAAIAPKDNLFIRFLKPWLGEGILLSGG 141 Query: 518 ADWVRHRRIINPVFTIDKLK 577 W RHRR++ P F + LK Sbjct: 142 DKWSRHRRMLTPAFHFNILK 161
>CP6D1_MUSDO (Q27698) Cytochrome P450 6d1 (EC 1.14.-.-) (CYPVID1) (Pyrethroid| resistance cytochrome P450) (Cytochrome P450 Ipr) Length = 516 Score = 34.3 bits (77), Expect = 0.29 Identities = 27/83 (32%), Positives = 38/83 (45%), Gaps = 8/83 (9%) Frame = +2 Query: 383 QPRICIFEYEMARQILSTKSGHF--------VKNDAHPTLLALVGKGLGFMEGADWVRHR 538 +P + + + E+ARQIL+T F KND + L MEG W R Sbjct: 74 KPALLVRDAELARQILTTDFNSFHDRGLYVDEKNDP-------MSANLFVMEGQSWRTLR 126 Query: 539 RIINPVFTIDKLKMMTKTMLDFA 607 + P F+ KLK M +T+ D A Sbjct: 127 MKLAPSFSSGKLKGMFETVDDVA 149
>CP17A_PANTR (Q8HYN1) Cytochrome P450 17A1 (EC 1.14.99.9) (CYPXVII) (P450-C17)| (P450c17) (Steroid 17-alpha-hydroxylase/17,20 lyase) Length = 508 Score = 33.9 bits (76), Expect = 0.38 Identities = 25/100 (25%), Positives = 46/100 (46%), Gaps = 6/100 (6%) Frame = +2 Query: 290 VGDHKYLPR---IAPHYLKWRAQHGEPFLYWHGPQPRICIFEYEMARQILSTKSGHFVKN 460 VG +LPR + ++ K + ++G + G + + + +++A+++L K F Sbjct: 37 VGSLPFLPRHGHMHNNFFKLQKKYGPIYSVRMGTKTTVIVGHHQLAKEVLIKKGKDFSGR 96 Query: 461 DAHPTLLALVG--KGLGFME-GADWVRHRRIINPVFTIDK 571 TL KG+ F + GA W HRR+ F + K Sbjct: 97 PQMATLDIASNNRKGIAFADSGAHWQLHRRLAMATFALFK 136
>CP17A_HUMAN (P05093) Cytochrome P450 17A1 (EC 1.14.99.9) (CYPXVII) (P450-C17)| (P450c17) (Steroid 17-alpha-monooxygenase) (Steroid 17-alpha-hydroxylase/17,20 lyase) Length = 508 Score = 33.9 bits (76), Expect = 0.38 Identities = 25/100 (25%), Positives = 46/100 (46%), Gaps = 6/100 (6%) Frame = +2 Query: 290 VGDHKYLPR---IAPHYLKWRAQHGEPFLYWHGPQPRICIFEYEMARQILSTKSGHFVKN 460 VG +LPR + ++ K + ++G + G + + + +++A+++L K F Sbjct: 37 VGSLPFLPRHGHMHNNFFKLQKKYGPIYSVRMGTKTTVIVGHHQLAKEVLIKKGKDFSGR 96 Query: 461 DAHPTLLALVG--KGLGFME-GADWVRHRRIINPVFTIDK 571 TL KG+ F + GA W HRR+ F + K Sbjct: 97 PQMATLDIASNNRKGIAFADSGAHWQLHRRLAMATFALFK 136
>CP4F5_RAT (P51870) Cytochrome P450 4F5 (EC 1.14.14.1) (CYPIVF5)| Length = 526 Score = 33.9 bits (76), Expect = 0.38 Identities = 15/34 (44%), Positives = 18/34 (52%) Frame = +2 Query: 488 VGKGLGFMEGADWVRHRRIINPVFTIDKLKMMTK 589 +G GL G W RHRR++ P F D LK K Sbjct: 132 LGDGLFLSSGDKWSRHRRLLTPAFHFDILKPYVK 165
>CP132_MYCTU (P77900) Putative cytochrome P450 132 (EC 1.14.-.-)| Length = 461 Score = 33.9 bits (76), Expect = 0.38 Identities = 17/51 (33%), Positives = 25/51 (49%) Frame = +2 Query: 449 FVKNDAHPTLLALVGKGLGFMEGADWVRHRRIINPVFTIDKLKMMTKTMLD 601 +VK+D + + A G L EG W RHR +N F L+ + M+D Sbjct: 76 YVKSDEYGPIRATAGLNLLTDEGDSWARHRGALNSTFARRHLRGLVGLMID 126
>CP132_MYCBO (P59954) Putative cytochrome P450 132 (EC 1.14.-.-)| Length = 461 Score = 33.9 bits (76), Expect = 0.38 Identities = 17/51 (33%), Positives = 25/51 (49%) Frame = +2 Query: 449 FVKNDAHPTLLALVGKGLGFMEGADWVRHRRIINPVFTIDKLKMMTKTMLD 601 +VK+D + + A G L EG W RHR +N F L+ + M+D Sbjct: 76 YVKSDEYGPIRATAGLNLLTDEGDSWARHRGALNSTFARRHLRGLVGLMID 126
>CP4E5_DROMT (O44221) Cytochrome P450 4e5, mitochondrial precursor (EC 1.14.-.-)| (CYPIVE5) Length = 522 Score = 33.9 bits (76), Expect = 0.38 Identities = 21/86 (24%), Positives = 40/86 (46%) Frame = +2 Query: 338 WRAQHGEPFLYWHGPQPRICIFEYEMARQILSTKSGHFVKNDAHPTLLALVGKGLGFMEG 517 W + + F W G I + + I+++ + K D + L +G+GL +G Sbjct: 62 WHKYNKDNFRIWIGYYANILVSNPKHLEVIMNSTT-LIEKLDIYDMLHPWLGEGLLTSKG 120 Query: 518 ADWVRHRRIINPVFTIDKLKMMTKTM 595 + W +HR++I P F + L+ + M Sbjct: 121 SKWHKHRKMITPTFHFNILQDFHQVM 146
>CP6A1_MUSDO (P13527) Cytochrome P450 6A1 (EC 1.14.14.1) (CYPVIA1)| Length = 509 Score = 33.9 bits (76), Expect = 0.38 Identities = 25/97 (25%), Positives = 45/97 (46%), Gaps = 2/97 (2%) Frame = +2 Query: 317 IAPHYLKWRAQHGEPFLYWHGPQPRICIFEYEMARQILSTKSGHFVKNDAHPTLL--ALV 490 IA +Y K++ P ++ G +P + + E+ +++L +F + L Sbjct: 59 IADYYRKFKGSDPLPGIFL-GHKPAAVVLDKELRKRVLIKDFSNFANRGLYYNEKDDPLT 117 Query: 491 GKGLGFMEGADWVRHRRIINPVFTIDKLKMMTKTMLD 601 G L +EG W R ++P FT K+K M T+L+ Sbjct: 118 GH-LVMVEGEKWRSLRTKLSPTFTAGKMKYMYNTVLE 153
>CP2G1_RAT (P10610) Cytochrome P450 2G1 (EC 1.14.14.1) (CYPIIG1) (P450-OLF1)| (Olfactive) Length = 494 Score = 33.5 bits (75), Expect = 0.49 Identities = 20/72 (27%), Positives = 33/72 (45%), Gaps = 1/72 (1%) Frame = +2 Query: 329 YLKWRAQHGEPFLYWHGPQPRICIFEYEMARQILSTKSGHFVKNDAHPTL-LALVGKGLG 505 +LK + ++G F + GP+P + + +E ++ L ++ F PTL G GL Sbjct: 58 FLKLQKKYGSVFTVYFGPRPVVILCGHEAVKEALVDQADDFSGRGEMPTLEKNFQGYGLA 117 Query: 506 FMEGADWVRHRR 541 G W RR Sbjct: 118 LSNGERWKILRR 129
>PLC1_YEAST (P32383) 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase| 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-1) (Phospholipase C-1) Length = 869 Score = 33.5 bits (75), Expect = 0.49 Identities = 13/39 (33%), Positives = 25/39 (64%) Frame = +2 Query: 257 IKEETDRLVLDVGDHKYLPRIAPHYLKWRAQHGEPFLYW 373 IK++ +L LD + +YL R+ PH L++++ + P +W Sbjct: 624 IKDKHLKLSLDKHNRRYLMRVYPHVLRYKSSNFNPIPFW 662
>CP4F3_HUMAN (Q08477) Cytochrome P450 4F3 (EC 1.14.13.30) (CYPIVF3)| (Leukotriene-B(4) omega-hydroxylase) (Leukotriene-B(4) 20-monooxygenase) (Cytochrome P450-LTB-omega) Length = 520 Score = 33.5 bits (75), Expect = 0.49 Identities = 24/81 (29%), Positives = 35/81 (43%), Gaps = 2/81 (2%) Frame = +2 Query: 353 GEPFLYWHGPQPRIC-IFEYEMARQILSTKSGHFVKNDAHPTLLA-LVGKGLGFMEGADW 526 G+ +W GP I IF + +L + K+ + L +G GL G W Sbjct: 85 GDMCCWWVGPWHAIVRIFHPTYIKPVLFAPAAIVPKDKVFYSFLKPWLGDGLLLSAGEKW 144 Query: 527 VRHRRIINPVFTIDKLKMMTK 589 RHRR++ P F + LK K Sbjct: 145 SRHRRMLTPAFHFNILKPYMK 165
>CP4V3_MOUSE (Q9DBW0) Cytochrome P450 4V3 (EC 1.14.-.-)| Length = 525 Score = 33.5 bits (75), Expect = 0.49 Identities = 19/63 (30%), Positives = 30/63 (47%) Frame = +2 Query: 371 WHGPQPRICIFEYEMARQILSTKSGHFVKNDAHPTLLALVGKGLGFMEGADWVRHRRIIN 550 W GP P + +++ E IL T S K+ + L +G GL G+ W R+++ Sbjct: 93 WIGPVPLVALYKAENVEVIL-TSSKQIDKSFLYKFLQPWLGLGLLTSTGSKWRTRRKMLT 151 Query: 551 PVF 559 P F Sbjct: 152 PTF 154
>NTHL1_HUMAN (P78549) Endonuclease III-like protein 1 (EC 4.2.99.18)| Length = 312 Score = 33.1 bits (74), Expect = 0.64 Identities = 24/75 (32%), Positives = 29/75 (38%), Gaps = 7/75 (9%) Frame = +1 Query: 100 GCSARGCRHAAVGLRRRAPRMEAVRHEQVVQRTRDPWTLLQVLERLQRGREEHQGGDRPS 279 G RGCR LRRR EA + V+R R + QR R ++G D Sbjct: 26 GAGPRGCREEPGPLRRREAAAEARKSHSPVKRPR----------KAQRLRVAYEGSDSEK 75 Query: 280 GAGR-------WRPQ 303 G G W PQ Sbjct: 76 GEGAEPLKVPVWEPQ 90
>CP4X1_RAT (Q8K4D6) Cytochrome P450 4X1 (EC 1.14.14.1) (CYPIVX1)| Length = 507 Score = 33.1 bits (74), Expect = 0.64 Identities = 22/73 (30%), Positives = 34/73 (46%), Gaps = 1/73 (1%) Frame = +2 Query: 362 FLYWHGP-QPRICIFEYEMARQILSTKSGHFVKNDAHPTLLALVGKGLGFMEGADWVRHR 538 F W GP Q I++ + A+ LS H + +G+GL ++G W +HR Sbjct: 80 FPCWVGPFQAFFYIYDPDYAKIFLSRTDPK--TQYLHQLMTPFLGRGLLNLDGPRWFQHR 137 Query: 539 RIINPVFTIDKLK 577 ++ P F D LK Sbjct: 138 CLLTPAFHQDILK 150
>CP134_DROME (Q9VG40) Probable cytochrome P450 313a4 (EC 1.14.-.-)| (CYPCCCXIIIA4) Length = 478 Score = 33.1 bits (74), Expect = 0.64 Identities = 20/72 (27%), Positives = 35/72 (48%), Gaps = 1/72 (1%) Frame = +2 Query: 347 QHGEPFLYWHGPQPRICIFEYEMARQILSTKSGHFV-KNDAHPTLLALVGKGLGFMEGAD 523 +HG W GP P + + + ++ + I + S H V K + + G GL ++ Sbjct: 63 KHGPTIFSWLGPIPFMIVSDPQVVQDIFT--SPHCVNKGIIYKAVDDGAGVGLFSLKDPR 120 Query: 524 WVRHRRIINPVF 559 W HR+++NP F Sbjct: 121 WSIHRKLLNPAF 132
>CP4FB_HUMAN (Q9HBI6) Cytochrome P450 4F11 (EC 1.14.14.1) (CYPIVF11)| Length = 524 Score = 33.1 bits (74), Expect = 0.64 Identities = 24/78 (30%), Positives = 35/78 (44%), Gaps = 2/78 (2%) Frame = +2 Query: 362 FLYWHGPQ-PRICIFEYEMARQILSTKSGHFVKNDA-HPTLLALVGKGLGFMEGADWVRH 535 F W GP P + + ++ R I S + K+ + L +G GL G W RH Sbjct: 88 FKLWLGPTFPLLILCHPDIIRPITSASAAVAPKDMIFYGFLKPWLGDGLLLSGGDKWSRH 147 Query: 536 RRIINPVFTIDKLKMMTK 589 RR++ P F + LK K Sbjct: 148 RRMLTPAFHFNILKPYMK 165
>CP6W1_DROME (Q9V9L1) Probable cytochrome P450 6w1 (EC 1.14.-.-) (CYPVIW1)| Length = 514 Score = 33.1 bits (74), Expect = 0.64 Identities = 25/86 (29%), Positives = 40/86 (46%), Gaps = 5/86 (5%) Frame = +2 Query: 356 EPFL-YWHGPQPRICIFEYEMARQILSTKSGHF----VKNDAHPTLLALVGKGLGFMEGA 520 EPF+ + +P + I + E+ + ++ K +F ++ D H L K L F Sbjct: 68 EPFVGVYMTHRPALVIRDLELIKTVMIKKFQYFNNRVLQTDPHNDALGY--KNLFFARSP 125 Query: 521 DWVRHRRIINPVFTIDKLKMMTKTML 598 W R I+PVFT K+K M M+ Sbjct: 126 GWRELRTKISPVFTSGKIKQMYPLMV 151
>CP4C1_BLADI (P29981) Cytochrome P450 4C1 (EC 1.14.14.1) (CYPIVC1)| Length = 511 Score = 33.1 bits (74), Expect = 0.64 Identities = 20/70 (28%), Positives = 32/70 (45%) Frame = +2 Query: 350 HGEPFLYWHGPQPRICIFEYEMARQILSTKSGHFVKNDAHPTLLALVGKGLGFMEGADWV 529 +G + W GP ++ + E IL H K+ + + +G+GL GA W Sbjct: 70 YGPLYRIWAGPIAQVGLTRPEHVELILRDTK-HIDKSLVYSFIRPWLGEGLLTGTGAKWH 128 Query: 530 RHRRIINPVF 559 HR++I P F Sbjct: 129 SHRKMITPTF 138
>CP315_DROME (Q9VGH1) Cytochrome P450 315a1, mitochondrial precursor (EC| 1.14.99.-) (CYPCCCXVA1) (Shadow protein) Length = 520 Score = 33.1 bits (74), Expect = 0.64 Identities = 14/30 (46%), Positives = 20/30 (66%) Frame = +2 Query: 494 KGLGFMEGADWVRHRRIINPVFTIDKLKMM 583 +GL FMEGA+W+ +RRI+N + L M Sbjct: 147 RGLFFMEGAEWLHNRRILNRLLLNGNLNWM 176
>CP4V2_PONPY (Q5RCN6) Cytochrome P450 4V2 (EC 1.14.-.-)| Length = 525 Score = 33.1 bits (74), Expect = 0.64 Identities = 19/63 (30%), Positives = 28/63 (44%) Frame = +2 Query: 371 WHGPQPRICIFEYEMARQILSTKSGHFVKNDAHPTLLALVGKGLGFMEGADWVRHRRIIN 550 W GP P + ++ E IL T S K+ + L +G GL G W R+++ Sbjct: 93 WVGPVPMVALYNAENVEVIL-TSSRQIDKSSMYKFLEPWLGLGLLTSTGNKWRSRRKMLT 151 Query: 551 PVF 559 P F Sbjct: 152 PTF 154
>CP4V2_HUMAN (Q6ZWL3) Cytochrome P450 4V2 (EC 1.14.-.-)| Length = 525 Score = 33.1 bits (74), Expect = 0.64 Identities = 19/63 (30%), Positives = 28/63 (44%) Frame = +2 Query: 371 WHGPQPRICIFEYEMARQILSTKSGHFVKNDAHPTLLALVGKGLGFMEGADWVRHRRIIN 550 W GP P + ++ E IL T S K+ + L +G GL G W R+++ Sbjct: 93 WVGPVPMVALYNAENVEVIL-TSSKQIDKSSMYKFLEPWLGLGLLTSTGNKWRSRRKMLT 151 Query: 551 PVF 559 P F Sbjct: 152 PTF 154
>CP240_MOUSE (P56657) Cytochrome P450 2C40 (EC 1.14.14.1) (CYPIIC40)| Length = 491 Score = 33.1 bits (74), Expect = 0.64 Identities = 22/77 (28%), Positives = 33/77 (42%), Gaps = 1/77 (1%) Frame = +2 Query: 350 HGEPFLYWHGPQPRICIFEYEMARQILSTKSGHFVKNDAHPTLLAL-VGKGLGFMEGADW 526 +G F + G QP + + YE ++ L F P + GKG+GF G W Sbjct: 61 YGPVFTLYFGSQPIVVLHGYEAIKEALIDHGEEFSGRGRIPVFDKVSTGKGIGFSHGNVW 120 Query: 527 VRHRRIINPVFTIDKLK 577 R VFT++ L+ Sbjct: 121 KATR-----VFTVNTLR 132
>THAS_PIG (P47787) Thromboxane-A synthase (EC 5.3.99.5) (TXA synthase) (TXS)| Length = 534 Score = 32.7 bits (73), Expect = 0.84 Identities = 20/86 (23%), Positives = 39/86 (45%) Frame = +2 Query: 329 YLKWRAQHGEPFLYWHGPQPRICIFEYEMARQILSTKSGHFVKNDAHPTLLALVGKGLGF 508 +++ R Q+G Y+ G + + I + +M +Q+L+ K +F A V + F Sbjct: 67 HMELRKQYGPLSGYYLGRRMIVVISDPDMIKQVLAEKFSNFTNRMATGLESKPVADSILF 126 Query: 509 MEGADWVRHRRIINPVFTIDKLKMMT 586 + W R ++ F+ KL +T Sbjct: 127 LRDKRWEEVRSVLTSAFSPKKLNKLT 152
>CP6A8_DROME (Q27593) Cytochrome P450 6a8 (EC 1.14.-.-) (CYPVIA8)| Length = 506 Score = 32.7 bits (73), Expect = 0.84 Identities = 25/100 (25%), Positives = 42/100 (42%), Gaps = 6/100 (6%) Frame = +2 Query: 326 HYLKWRAQHGEPFLYWHGPQPRICIFEYEMARQILS------TKSGHFVKNDAHPTLLAL 487 HY K+R ++ P + + E+A+QIL + G F P Sbjct: 62 HYNKFRESKAPFVGFFFFQSPAAFVIDLELAKQILIKDFSNFSNKGIFYNEKDDP----- 116 Query: 488 VGKGLGFMEGADWVRHRRIINPVFTIDKLKMMTKTMLDFA 607 + L ++GA W R ++ FT K+K+M T++ A Sbjct: 117 ISAHLFNLDGAQWRLLRNKLSSTFTSGKMKLMYPTVVSVA 156
>CP133_DROME (Q9VGB3) Probable cytochrome P450 313a3 (EC 1.14.-.-)| (CYPCCCXIIIA3) Length = 492 Score = 32.7 bits (73), Expect = 0.84 Identities = 19/75 (25%), Positives = 34/75 (45%) Frame = +2 Query: 335 KWRAQHGEPFLYWHGPQPRICIFEYEMARQILSTKSGHFVKNDAHPTLLALVGKGLGFME 514 K+ +G L W GP P + + ++A +I + + + + G GL +E Sbjct: 60 KYMDIYGSTCLVWVGPTPFVITRDPKIAEEIFLSPECLNRSSIFSKPVNSCTGDGLLSLE 119 Query: 515 GADWVRHRRIINPVF 559 + WV R+ +NP F Sbjct: 120 ASKWVDRRKNLNPAF 134
>C6A14_DROME (Q9V4U7) Probable cytochrome P450 6a14 (EC 1.14.-.-) (CYPVIA14)| Length = 509 Score = 32.7 bits (73), Expect = 0.84 Identities = 13/31 (41%), Positives = 20/31 (64%) Frame = +2 Query: 509 MEGADWVRHRRIINPVFTIDKLKMMTKTMLD 601 +EG +W R + PVFT K+K M+K ++D Sbjct: 120 LEGEEWRAMRHKLTPVFTSGKIKQMSKVIVD 150
>CP3AS_BOVIN (P79102) Cytochrome P450 3A28 (EC 1.14.14.1) (CYPIIIA28)| Length = 507 Score = 32.3 bits (72), Expect = 1.1 Identities = 21/95 (22%), Positives = 42/95 (44%) Frame = +2 Query: 299 HKYLPRIAPHYLKWRAQHGEPFLYWHGPQPRICIFEYEMARQILSTKSGHFVKNDAHPTL 478 HK +P K ++G+ + ++ G QP + I + ++ + +L + N Sbjct: 54 HKGIPEFDNQCFK---KYGKMWGFYEGRQPMLAITDPDIIKTVLVKECYSVFTNRRIFGP 110 Query: 479 LALVGKGLGFMEGADWVRHRRIINPVFTIDKLKMM 583 + ++ + W R R +++P FT KLK M Sbjct: 111 MGIMKYAISLAWDEQWKRIRTLLSPAFTSGKLKEM 145
>CENPB_HUMAN (P07199) Major centromere autoantigen B (Centromere protein B)| (CENP-B) Length = 599 Score = 32.3 bits (72), Expect = 1.1 Identities = 22/78 (28%), Positives = 35/78 (44%) Frame = -1 Query: 265 LLDAPHVLVAAFQEPVGGSMDPLFSEPLAHGVRPPYEAHDGVVPQLRAGNREQSNQNEEE 86 L +A H + AA+Q + F E G P + + L++ E+ + EEE Sbjct: 361 LTEALHFVAAAWQAVEPSDIAACFREA-GFGGGP----NATITTSLKSEGEEEEEEEEEE 415 Query: 85 HSKEGHGRGQEEDGGVSE 32 +EG G +EE+G E Sbjct: 416 EEEEGEGEEEEEEGEEEE 433
>AMELX_HUMAN (Q99217) Amelogenin, X isoform precursor| Length = 191 Score = 32.3 bits (72), Expect = 1.1 Identities = 19/73 (26%), Positives = 31/73 (42%), Gaps = 6/73 (8%) Frame = -1 Query: 364 KWFSVLSPPFEVVGRDP------REVLVVANVQHQTVGLLLDAPHVLVAAFQEPVGGSMD 203 KW+ + PP+ G +P +++ V + QH L H+ V Q+PV Sbjct: 40 KWYQSIRPPYPSYGYEPMGGWLHHQIIPVLSQQHPPTHTLQPHHHIPVVPAQQPV-IPQQ 98 Query: 202 PLFSEPLAHGVRP 164 P+ P H + P Sbjct: 99 PMMPVPGQHSMTP 111
>F10A1_RAT (P50503) Hsc70-interacting protein (Hip) (Protein ST13 homolog)| (Protein FAM10A1) Length = 368 Score = 32.0 bits (71), Expect = 1.4 Identities = 17/56 (30%), Positives = 30/56 (53%), Gaps = 1/56 (1%) Frame = +1 Query: 127 AAVGLRRRAPRMEAV-RHEQVVQRTRDPWTLLQVLERLQRGREEHQGGDRPSGAGR 291 A+ LR PR + + H + +R R+ + + +ER+++ REEH+ R A R Sbjct: 216 ASAMLREVQPRAQKIAEHRRKYERKREEREIKERIERVKKAREEHEKAQREEEARR 271
>PLC1_CANAL (O13433) 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase| 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-1) (Phospholipase C-1) Length = 1099 Score = 32.0 bits (71), Expect = 1.4 Identities = 15/46 (32%), Positives = 26/46 (56%), Gaps = 1/46 (2%) Frame = +2 Query: 251 RSIKEETDRLVLDVGDHKYLPRIAPHYLKWRAQHGEPFLYW-HGPQ 385 R IK++ ++ LD + +YL R+ P + ++ + P YW HG Q Sbjct: 831 RMIKDDDKKISLDKHNRRYLMRVYPSGTRLKSSNFNPLPYWSHGVQ 876
>F10A1_MOUSE (Q99L47) Hsc70-interacting protein (Hip) (Protein ST13 homolog)| (Protein FAM10A1) Length = 371 Score = 32.0 bits (71), Expect = 1.4 Identities = 17/56 (30%), Positives = 30/56 (53%), Gaps = 1/56 (1%) Frame = +1 Query: 127 AAVGLRRRAPRMEAV-RHEQVVQRTRDPWTLLQVLERLQRGREEHQGGDRPSGAGR 291 A+ LR PR + + H + +R R+ + + +ER+++ REEH+ R A R Sbjct: 216 ASAMLREVQPRAQKIAEHRRKYERKREEREIKERIERVKKAREEHERAQREEEARR 271
>C4G15_DROME (Q9VYY4) Cytochrome P450 4g15 (EC 1.14.-.-) (CYPIVG15)| Length = 574 Score = 31.6 bits (70), Expect = 1.9 Identities = 19/69 (27%), Positives = 32/69 (46%) Frame = +2 Query: 371 WHGPQPRICIFEYEMARQILSTKSGHFVKNDAHPTLLALVGKGLGFMEGADWVRHRRIIN 550 W GP+ + I++ +LS+ + K + +G GL G W HR++I Sbjct: 86 WIGPKLVVFIYDPRDVELLLSSHV-YIDKASEYKFFKPWLGDGLLISTGQKWRSHRKLIA 144 Query: 551 PVFTIDKLK 577 P F ++ LK Sbjct: 145 PTFHLNVLK 153
>CP3AG_MOUSE (Q64481) Cytochrome P450 3A16 (EC 1.14.14.1) (CYPIIIA16)| Length = 504 Score = 31.6 bits (70), Expect = 1.9 Identities = 17/79 (21%), Positives = 36/79 (45%) Frame = +2 Query: 347 QHGEPFLYWHGPQPRICIFEYEMARQILSTKSGHFVKNDAHPTLLALVGKGLGFMEGADW 526 ++G+ + + G P I + E + +L + N + ++ K + + +W Sbjct: 67 KYGKTWGLFDGQIPLFVITDPETIKNVLVKECFSVFTNRQDFFPVGIMSKSISLAKDEEW 126 Query: 527 VRHRRIINPVFTIDKLKMM 583 R+R +++P FT LK M Sbjct: 127 KRYRALLSPTFTSGNLKEM 145
>CP3A5_HUMAN (P20815) Cytochrome P450 3A5 (EC 1.14.14.1) (CYPIIIA5) (P450-PCN3)| (HLp2) Length = 502 Score = 31.6 bits (70), Expect = 1.9 Identities = 18/79 (22%), Positives = 36/79 (45%) Frame = +2 Query: 347 QHGEPFLYWHGPQPRICIFEYEMARQILSTKSGHFVKNDAHPTLLALVGKGLGFMEGADW 526 ++G+ + + G P + I + ++ R +L + N + + + E +W Sbjct: 67 KYGKMWGTYEGQLPVLAITDPDVIRTVLVKECYSVFTNRRSLGPVGFMKSAISLAEDEEW 126 Query: 527 VRHRRIINPVFTIDKLKMM 583 R R +++P FT KLK M Sbjct: 127 KRIRSLLSPTFTSGKLKEM 145
>CP4F6_RAT (P51871) Cytochrome P450 4F6 (EC 1.14.14.1) (CYPIVF6)| Length = 537 Score = 31.6 bits (70), Expect = 1.9 Identities = 14/34 (41%), Positives = 17/34 (50%) Frame = +2 Query: 488 VGKGLGFMEGADWVRHRRIINPVFTIDKLKMMTK 589 +G GL G W HRR++ P F D LK K Sbjct: 132 LGDGLLMSAGEKWNHHRRLLTPAFHFDILKSYVK 165
>CP4G1_DROME (Q9V3S0) Cytochrome P450 4g1 (EC 1.14.-.-) (CYPIVG1)| Length = 556 Score = 31.6 bits (70), Expect = 1.9 Identities = 23/85 (27%), Positives = 32/85 (37%) Frame = +2 Query: 347 QHGEPFLYWHGPQPRICIFEYEMARQILSTKSGHFVKNDAHPTLLALVGKGLGFMEGADW 526 ++GE W G + + ILS H K + + G GL G W Sbjct: 90 KYGETMKAWLGNVLLVFLTNPSDIELILSGHQ-HLTKAEEYRYFKPWFGDGLLISNGHHW 148 Query: 527 VRHRRIINPVFTIDKLKMMTKTMLD 601 HR++I P F LK T +D Sbjct: 149 RHHRKMIAPTFHQSILKSFVPTFVD 173
>CP6D3_MUSDO (Q964Q7) Cytochrome P450 6d3 (EC 1.14.-.-) (CYPVID3) (Pyrethroid| resistance cytochrome P450) Length = 520 Score = 31.6 bits (70), Expect = 1.9 Identities = 29/99 (29%), Positives = 46/99 (46%), Gaps = 8/99 (8%) Frame = +2 Query: 329 YLKWRAQHGEPFLYWHGPQPRICIFEYEMARQILSTKSGHF--------VKNDAHPTLLA 484 Y K++ Q +L++ +P + I + E+ARQIL++ F KND Sbjct: 59 YEKFQEQVVGIYLFF---KPALLIRDAELARQILTSDFNSFHDRGIYVDEKNDP------ 109 Query: 485 LVGKGLGFMEGADWVRHRRIINPVFTIDKLKMMTKTMLD 601 + L +EG W R + P F+ KLK M +T+ D Sbjct: 110 -MSANLFALEGQSWRTLRMKLTPSFSSGKLKGMFETVDD 147
>CP3AO_SHEEP (Q29496) Cytochrome P450 3A24 (EC 1.14.14.1) (CYPIIIA24)| Length = 503 Score = 31.2 bits (69), Expect = 2.4 Identities = 18/79 (22%), Positives = 37/79 (46%) Frame = +2 Query: 347 QHGEPFLYWHGPQPRICIFEYEMARQILSTKSGHFVKNDAHPTLLALVGKGLGFMEGADW 526 ++G+ + + G QP + I + ++ + +L + N + ++ + E W Sbjct: 67 KYGKMWGVFEGKQPLLVITDPDVIKTVLVKECYSVFTNRRVFGPMGIMKNAVSVAEDEQW 126 Query: 527 VRHRRIINPVFTIDKLKMM 583 R R +++P FT KLK M Sbjct: 127 KRIRTLLSPTFTSGKLKDM 145
>CP3A7_HUMAN (P24462) Cytochrome P450 3A7 (EC 1.14.14.1) (CYPIIIA7) (P450-HFLA)| Length = 503 Score = 31.2 bits (69), Expect = 2.4 Identities = 17/74 (22%), Positives = 32/74 (43%) Frame = +2 Query: 383 QPRICIFEYEMARQILSTKSGHFVKNDAHPTLLALVGKGLGFMEGADWVRHRRIINPVFT 562 QP + I + +M + +L + N + + + E +W R R +++P FT Sbjct: 79 QPMLAITDPDMIKTVLVKECYSVFTNRRPFGPVGFMKNAISIAEDEEWKRIRSLLSPTFT 138 Query: 563 IDKLKMMTKTMLDF 604 KLK M + + Sbjct: 139 SGKLKEMVPIIAQY 152
>C13A8_CAEEL (Q27516) Putative cytochrome P450 CYP13A8 (EC 1.14.-.-)| Length = 509 Score = 31.2 bits (69), Expect = 2.4 Identities = 23/97 (23%), Positives = 43/97 (44%), Gaps = 8/97 (8%) Frame = +2 Query: 335 KWRAQHGEPFLYWHGPQPRICIFEYEMARQILSTKSGHFVKNDAHPTL--------LALV 490 KW ++G+ + + G Q + I + ++ ++IL + +F +P + +V Sbjct: 54 KWTKEYGKIYGFTEGMQKVMVISDPDLVQEILVKQYDNFYGRKHNPVQGDPDKDKDIHIV 113 Query: 491 GKGLGFMEGADWVRHRRIINPVFTIDKLKMMTKTMLD 601 G +G W R R I P F+ +K + TM D Sbjct: 114 GA-----QGFRWKRLRTITAPAFSNGSIKKVLTTMED 145
>C6A22_DROME (Q9V769) Cytochrome P450 6a22 (EC 1.14.-.-) (CYPVIA22)| Length = 499 Score = 30.8 bits (68), Expect = 3.2 Identities = 37/144 (25%), Positives = 62/144 (43%), Gaps = 3/144 (2%) Frame = +2 Query: 179 SKWFREQGIHGPSYRFLKGCNEDVRSIKEETDRLVLDVGDHKYLPRIAPHYLKWRAQHGE 358 S W R +GI RF G E R K ++ + P Y K++ +G Sbjct: 24 SYWTR-RGIGSEPARFPVGNMEGFRKNKH-------------FIDIVTPIYEKFKG-NGA 68 Query: 359 PFL-YWHGPQPRICIFEYEMARQILSTKSGHFVKNDAHPTLL--ALVGKGLGFMEGADWV 529 PF ++ +P + + + E+A+QIL +F + L G L ++G W Sbjct: 69 PFAGFFMMLRPVVLVTDLELAKQILIQDFANFEDRGMYHNERDDPLTGH-LFRIDGPKWR 127 Query: 530 RHRRIINPVFTIDKLKMMTKTMLD 601 R+ ++P FT K+K M T+ + Sbjct: 128 PLRQKMSPTFTSAKMKYMFPTVCE 151
>CP3AH_CAVPO (Q64409) Cytochrome P450 3A17 (EC 1.14.14.1) (CYPIIIA17)| Length = 503 Score = 30.8 bits (68), Expect = 3.2 Identities = 20/79 (25%), Positives = 35/79 (44%) Frame = +2 Query: 347 QHGEPFLYWHGPQPRICIFEYEMARQILSTKSGHFVKNDAHPTLLALVGKGLGFMEGADW 526 ++G + + GP+P + I E +M + +L + N + K L + +W Sbjct: 67 KYGNMWGLYDGPRPVLSITEPDMIKAVLVKECYSVFTNRRSIFPAGFMKKALSISKDEEW 126 Query: 527 VRHRRIINPVFTIDKLKMM 583 R R ++ FT KLK M Sbjct: 127 KRIRTQLSQNFTSGKLKEM 145
>CP3AA_MESAU (Q64148) Cytochrome P450 3A10 (EC 1.14.13.94) (CYPIIIA10)| (Lithocholate 6-beta-hydroxylase) (6 beta-hydroxylase) Length = 503 Score = 30.8 bits (68), Expect = 3.2 Identities = 18/79 (22%), Positives = 38/79 (48%) Frame = +2 Query: 347 QHGEPFLYWHGPQPRICIFEYEMARQILSTKSGHFVKNDAHPTLLALVGKGLGFMEGADW 526 ++G+ + ++ G P + I + E+ + +L + N + + K + + +W Sbjct: 67 KYGKIWGFYDGRVPVLAIADPEIIKTVLVKECYSNFTNRRSFGPVGFMKKSITISKDEEW 126 Query: 527 VRHRRIINPVFTIDKLKMM 583 R R +++P FT KLK M Sbjct: 127 KRLRTLLSPAFTSGKLKEM 145
>F10A1_HUMAN (P50502) Hsc70-interacting protein (Hip) (Suppression of| tumorigenicity protein 13) (Putative tumor suppressor ST13) (Protein FAM10A1) (Progesterone receptor-associated p48 protein) (NY-REN-33 antigen) Length = 369 Score = 30.8 bits (68), Expect = 3.2 Identities = 16/56 (28%), Positives = 30/56 (53%), Gaps = 1/56 (1%) Frame = +1 Query: 127 AAVGLRRRAPRMEAV-RHEQVVQRTRDPWTLLQVLERLQRGREEHQGGDRPSGAGR 291 A+ L+ PR + + H + +R R+ + + +ER+++ REEH+ R A R Sbjct: 217 ASAMLKEVQPRAQKIAEHRRKYERKREEREIKERIERVKKAREEHERAQREEEARR 272
>CENPB_SHEEP (P49451) Major centromere autoantigen B (Centromere protein B)| (CENP-B) (Fragment) Length = 239 Score = 30.8 bits (68), Expect = 3.2 Identities = 12/37 (32%), Positives = 20/37 (54%) Frame = -1 Query: 142 VVPQLRAGNREQSNQNEEEHSKEGHGRGQEEDGGVSE 32 + L++ E+ + EEE +EG G +EE+ G E Sbjct: 38 ITTALKSEGEEEEEEEEEEEEEEGEGEEEEEEDGEEE 74
>F10A1_CHICK (Q5ZLF0) Hsc70-interacting protein (Hip) (Protein ST13 homolog)| (Protein FAM10A1) Length = 361 Score = 30.8 bits (68), Expect = 3.2 Identities = 16/56 (28%), Positives = 30/56 (53%), Gaps = 1/56 (1%) Frame = +1 Query: 127 AAVGLRRRAPRMEAV-RHEQVVQRTRDPWTLLQVLERLQRGREEHQGGDRPSGAGR 291 A+ L+ PR + + H + +R R+ + + +ER+++ REEH+ R A R Sbjct: 215 ASAMLKEVQPRAQKIAEHRRKYERKREEKEIKERMERVKKAREEHERAQREEEARR 270
>CP6D4_DROME (Q9VCW1) Probable cytochrome P450 6d4 (EC 1.14.-.-) (CYPVID4)| Length = 515 Score = 30.4 bits (67), Expect = 4.2 Identities = 20/79 (25%), Positives = 36/79 (45%), Gaps = 6/79 (7%) Frame = +2 Query: 383 QPRICIFEYEMARQILSTK------SGHFVKNDAHPTLLALVGKGLGFMEGADWVRHRRI 544 +P + I + ++AR++L+ G +V + P + + + G W R + Sbjct: 77 RPAVLIRDADLARRVLAQDFASFHDRGVYVDEERDP-----LSANIFSLRGQSWRSMRHM 131 Query: 545 INPVFTIDKLKMMTKTMLD 601 ++P FT KLK M T D Sbjct: 132 LSPCFTSGKLKSMFSTSED 150
>CP6J1_BLAGE (Q964R1) Cytochrome P450 6j1 (EC 1.14.-.-) (CYPVIJ1)| Length = 501 Score = 30.4 bits (67), Expect = 4.2 Identities = 18/69 (26%), Positives = 30/69 (43%), Gaps = 2/69 (2%) Frame = +2 Query: 383 QPRICIFEYEMARQILSTKSGHFVKN--DAHPTLLALVGKGLGFMEGADWVRHRRIINPV 556 QP + + + E+ + IL S +F+ +L L + + G W R + P Sbjct: 84 QPALLVNDLEIVKNILVKDSRNFIDRMVKVDESLSPLNANAIFALRGQKWKHVRTSLTPT 143 Query: 557 FTIDKLKMM 583 FT K+K M Sbjct: 144 FTTGKMKNM 152
>CP4D2_DROME (Q27589) Cytochrome P450 4d2 (EC 1.14.-.-) (CYPIVD2)| Length = 501 Score = 30.4 bits (67), Expect = 4.2 Identities = 16/45 (35%), Positives = 23/45 (51%) Frame = +2 Query: 425 ILSTKSGHFVKNDAHPTLLALVGKGLGFMEGADWVRHRRIINPVF 559 +LS++ H KN+ + L +G GL G W R+II P F Sbjct: 90 VLSSQQ-HITKNNLYKLLNCWLGDGLLMSTGRKWHGRRKIITPTF 133
>CP4CU_BLAGE (Q964T1) Cytochrome P450 4c21 (EC 1.14.14.1) (CYPIVC21)| Length = 501 Score = 30.4 bits (67), Expect = 4.2 Identities = 20/69 (28%), Positives = 32/69 (46%), Gaps = 1/69 (1%) Frame = +2 Query: 356 EPFLYWH-GPQPRICIFEYEMARQILSTKSGHFVKNDAHPTLLALVGKGLGFMEGADWVR 532 +P + W+ G +P + I E+ +L K + + +G GL GA W + Sbjct: 69 KPLILWYFGNRPFVNISSPELIEVVLRNTQ-LIDKAFLYDLFHSWLGTGLLTSSGAKWHQ 127 Query: 533 HRRIINPVF 559 HR+II P F Sbjct: 128 HRKIITPTF 136
>CP9F2_DROME (Q9VG82) Probable cytochrome P450 9f2 (EC 1.14.-.-) (CYPIXF2)| Length = 516 Score = 30.4 bits (67), Expect = 4.2 Identities = 21/81 (25%), Positives = 35/81 (43%), Gaps = 10/81 (12%) Frame = +2 Query: 383 QPRICIFEYEMARQILSTKSGHFVKN----------DAHPTLLALVGKGLGFMEGADWVR 532 QP + + + ++ +QI HF+ + D H + L G L M A W Sbjct: 78 QPLLMVRDPDLIKQITIKDFDHFINHRNVFATSSDDDPHD-MSNLFGSSLFSMRDARWKD 136 Query: 533 HRRIINPVFTIDKLKMMTKTM 595 R ++P FT K++ M + M Sbjct: 137 MRSTLSPAFTGSKMRQMFQLM 157
>CP6A2_DROME (P33270) Cytochrome P450 6a2 (EC 1.14.-.-) (CYPVIA2) (P450-B1)| Length = 506 Score = 30.4 bits (67), Expect = 4.2 Identities = 24/93 (25%), Positives = 46/93 (49%), Gaps = 2/93 (2%) Frame = +2 Query: 326 HYLKWRAQHGEPFL-YWHGPQPRICIFEYEMARQILSTKSGHFV-KNDAHPTLLALVGKG 499 +Y K+R + G PF+ ++ +P I + ++A+ IL +F + H + + Sbjct: 59 YYNKYR-KSGFPFVGFYFLHKPAAFIVDTQLAKNILIKDFSNFADRGQFHNGRDDPLTQH 117 Query: 500 LGFMEGADWVRHRRIINPVFTIDKLKMMTKTML 598 L ++G W R+ + P FT K+K M T++ Sbjct: 118 LFNLDGKKWKDMRQRLTPTFTSGKMKFMFPTVI 150
>AXN1_RAT (O70239) Axin-1 (Axis inhibition protein 1) (rAxin)| Length = 827 Score = 30.0 bits (66), Expect = 5.4 Identities = 22/53 (41%), Positives = 29/53 (54%), Gaps = 4/53 (7%) Frame = +1 Query: 163 EAVRHEQVVQRTRDPWTLLQVLERLQRGREEHQG--GDRPSG--AGRWRPQVP 309 E + + VQRTR+ L+ ERL+R R E +G G+ PSG A P VP Sbjct: 391 ELIHRLEAVQRTREAEEKLE--ERLKRVRMEEEGEDGEMPSGPMASHKLPSVP 441
>PVRL1_HUMAN (Q15223) Poliovirus receptor-related protein 1 precursor (Herpes| virus entry mediator C) (HveC) (Nectin-1) (Herpesvirus Ig-like receptor) (HIgR) (CD111 antigen) Length = 517 Score = 30.0 bits (66), Expect = 5.4 Identities = 17/54 (31%), Positives = 28/54 (51%) Frame = -1 Query: 202 PLFSEPLAHGVRPPYEAHDGVVPQLRAGNREQSNQNEEEHSKEGHGRGQEEDGG 41 P P+A ++ P ++ D + +AG S+ EEE +EG G G+ + GG Sbjct: 406 PQHHPPMAQNLQYPDDSDD----EKKAGPLGGSSYEEEEEEEEGGGGGERKVGG 455
>AXN1_MOUSE (O35625) Axin-1 (Axis inhibition protein 1) (Fused protein)| Length = 863 Score = 30.0 bits (66), Expect = 5.4 Identities = 22/53 (41%), Positives = 29/53 (54%), Gaps = 4/53 (7%) Frame = +1 Query: 163 EAVRHEQVVQRTRDPWTLLQVLERLQRGREEHQG--GDRPSG--AGRWRPQVP 309 E + + VQRTR+ L+ ERL+R R E +G G+ PSG A P VP Sbjct: 391 ELIHRLEAVQRTREAEEKLE--ERLKRVRMEEEGEDGEMPSGPMASHKLPSVP 441
>BACC_BACLI (O68008) Bacitracin synthetase 3 (BA3) [Includes: ATP-dependent| isoleucine adenylase (IleA) (Isoleucine activase); ATP-dependent D-phenylalanine adenylase (D-PheA) (D-phenylalanine activase); ATP-dependent histidine adenylase (HisA) (Histidine Length = 6359 Score = 30.0 bits (66), Expect = 5.4 Identities = 16/47 (34%), Positives = 23/47 (48%) Frame = -1 Query: 157 EAHDGVVPQLRAGNREQSNQNEEEHSKEGHGRGQEEDGGVSESCVVW 17 E +D ++ L R+ + QN+ + EGHGR Q DG V W Sbjct: 4866 EINDILITALLVAARDMNGQNQLRITLEGHGREQVADGIDISRTVGW 4912
>CP3AL_CALJA (O18993) Cytochrome P450 3A21 (EC 1.14.14.1) (CYPIIIA21) (P450| CM3A-10) Length = 503 Score = 30.0 bits (66), Expect = 5.4 Identities = 17/86 (19%), Positives = 38/86 (44%) Frame = +2 Query: 347 QHGEPFLYWHGPQPRICIFEYEMARQILSTKSGHFVKNDAHPTLLALVGKGLGFMEGADW 526 ++G+ + + G QP + I + + + +L + N + + + + +W Sbjct: 67 KYGKMWGIYDGRQPVLAITDPNIIKTVLVKECYSVFTNRRPFGPVGFMKSAISIAQDDEW 126 Query: 527 VRHRRIINPVFTIDKLKMMTKTMLDF 604 R R +++P FT KLK M + + Sbjct: 127 KRIRSLLSPTFTSGKLKEMVPIIAQY 152
>Y020_YERPS (Q66GG2) UPF0241 protein YPTB0020| Length = 188 Score = 30.0 bits (66), Expect = 5.4 Identities = 16/46 (34%), Positives = 23/46 (50%) Frame = -1 Query: 157 EAHDGVVPQLRAGNREQSNQNEEEHSKEGHGRGQEEDGGVSESCVV 20 EA D + +GNR + N E +K+GH + QE+D V V Sbjct: 34 EARDRKRQKKHSGNRSGARTNVEGSNKKGHSQTQEKDPRVGSKVPV 79
>Y020_YERPE (Q8ZJR9) UPF0241 protein YPO0020/y3808/YP0021| Length = 188 Score = 30.0 bits (66), Expect = 5.4 Identities = 16/46 (34%), Positives = 23/46 (50%) Frame = -1 Query: 157 EAHDGVVPQLRAGNREQSNQNEEEHSKEGHGRGQEEDGGVSESCVV 20 EA D + +GNR + N E +K+GH + QE+D V V Sbjct: 34 EARDRKRQKKHSGNRSGARTNVEGSNKKGHSQTQEKDPRVGSKVPV 79
>DOS_HUMAN (Q8N350) Protein Dos| Length = 725 Score = 30.0 bits (66), Expect = 5.4 Identities = 33/107 (30%), Positives = 43/107 (40%), Gaps = 12/107 (11%) Frame = +1 Query: 85 APPRSGCSARGCRHAAVGLRRRAPRMEAVRHEQVVQRTRDPWTLLQVLERLQRGREEHQ- 261 +PP G + G L A R EQ RD W+L LE L +H Sbjct: 419 SPPERGAGSAGPEQQQPPLEPDAERDAGP--EQAQTSYRDLWSLRASLE-LHAAASDHSS 475 Query: 262 -GGDRPS---------GAGRWRPQV-PPADRAPLPQMEGSARRTISI 369 G DR S G+G P PP+ AP P+ +G ARR + + Sbjct: 476 SGNDRDSVRSGDSSGSGSGGAAPAFPPPSPPAPRPK-DGEARRLLQM 521
>CLH_CAEEL (P34574) Probable clathrin heavy chain protein 1| Length = 1681 Score = 30.0 bits (66), Expect = 5.4 Identities = 17/52 (32%), Positives = 26/52 (50%) Frame = +1 Query: 184 VVQRTRDPWTLLQVLERLQRGREEHQGGDRPSGAGRWRPQVPPADRAPLPQM 339 ++Q RD T L+ LER + R+E + + + PQ+ AP PQM Sbjct: 1601 MIQVMRDYQTRLEKLERSEHERKEEKAEQQQNNGMTMEPQLMLTYGAPAPQM 1652
>GAG_RSVP (P03322) Gag polyprotein [Contains: Core protein p19; Core protein| p2A; Core protein p2B; Core protein p10; Capsid protein p27; Inner coat protein p12; Protease p15 (EC 3.4.23.-)] Length = 701 Score = 29.6 bits (65), Expect = 7.1 Identities = 15/37 (40%), Positives = 21/37 (56%) Frame = +1 Query: 244 GREEHQGGDRPSGAGRWRPQVPPADRAPLPQMEGSAR 354 G ++ QGGD P GA + R + A +AP P + AR Sbjct: 188 GEQQGQGGDTPPGAEQSRAEPGHAGQAPGPALTDWAR 224
>SET1A_HUMAN (O15047) Histone-lysine N-methyltransferase, H3 lysine-4 specific| SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A) Length = 1707 Score = 29.6 bits (65), Expect = 7.1 Identities = 27/96 (28%), Positives = 39/96 (40%) Frame = -1 Query: 316 PREVLVVANVQHQTVGLLLDAPHVLVAAFQEPVGGSMDPLFSEPLAHGVRPPYEAHDGVV 137 PR +L ++H + P EPV LFS P + EA + VV Sbjct: 1289 PRPLLSHILLEHNYALAVKPTPPAPALRPPEPVPAPA-ALFSSPADEVL----EAPEVVV 1343 Query: 136 PQLRAGNREQSNQNEEEHSKEGHGRGQEEDGGVSES 29 + +Q Q EE +EG G+EE+ S+S Sbjct: 1344 AEAEEPKPQQLQQQREEGEEEGEEEGEEEEEESSDS 1379
>MEF2D_HUMAN (Q14814) Myocyte-specific enhancer factor 2D| Length = 521 Score = 29.6 bits (65), Expect = 7.1 Identities = 14/41 (34%), Positives = 22/41 (53%) Frame = +1 Query: 256 HQGGDRPSGAGRWRPQVPPADRAPLPQMEGSARRTISILAW 378 ++ GDR G G + P + AP P+ EGSA + + + W Sbjct: 478 YETGDRDDGRGDFGPTLGLLRPAPEPEAEGSAVKRMRLDTW 518
>NEDD4_DROME (Q9VVI3) E3 ubiquitin-protein ligase Nedd-4 (EC 6.3.2.-) (DNedd4)| Length = 1007 Score = 29.6 bits (65), Expect = 7.1 Identities = 26/83 (31%), Positives = 38/83 (45%), Gaps = 1/83 (1%) Frame = +1 Query: 250 EEHQGGDRPSGAGRWRPQVPPADRAPLPQMEGSARRTISILAWATATNLHI*VRNGKANP 429 E++ GG+ RW QV P R ++ ++RRT W I RNG+A+P Sbjct: 521 EQNTGGEEEPLPPRWSMQVAPNGRTFF--IDHASRRT----TW-------IDPRNGRASP 567 Query: 430 F-NQVRTFREERCTPNPLGFGWQ 495 NQ R ++ PL GW+ Sbjct: 568 MPNQTRRVEDDL---GPLPEGWE 587
>MEF2D_MOUSE (Q63943) Myocyte-specific enhancer factor 2D| Length = 514 Score = 29.6 bits (65), Expect = 7.1 Identities = 14/41 (34%), Positives = 22/41 (53%) Frame = +1 Query: 256 HQGGDRPSGAGRWRPQVPPADRAPLPQMEGSARRTISILAW 378 ++ GDR G G + P + AP P+ EGSA + + + W Sbjct: 471 YETGDRDDGRGDFGPTLGLLRPAPEPEAEGSAVKRMRLDTW 511
>F10A1_PONPY (Q5RF31) Hsc70-interacting protein (Hip) (Protein ST13 homolog)| (Protein FAM10A1) Length = 369 Score = 29.6 bits (65), Expect = 7.1 Identities = 15/56 (26%), Positives = 30/56 (53%), Gaps = 1/56 (1%) Frame = +1 Query: 127 AAVGLRRRAPRMEAV-RHEQVVQRTRDPWTLLQVLERLQRGREEHQGGDRPSGAGR 291 A+ L+ P+ + + H + +R R+ + + +ER+++ REEH+ R A R Sbjct: 217 ASAMLKEVQPKAQKIAEHRRKYERKREEREIKERIERVKKAREEHERAQREEEARR 272
>MYOB_DICDI (P34092) Myosin IB heavy chain| Length = 1111 Score = 29.6 bits (65), Expect = 7.1 Identities = 17/53 (32%), Positives = 27/53 (50%), Gaps = 2/53 (3%) Frame = +1 Query: 202 DPWTLLQVLERLQRGREEHQGGDRPSGAGRWRPQVPPADRAPLPQME--GSAR 354 +P ++ Q R + +G P GAG+ +PQ P + P+PQ + G AR Sbjct: 926 NPNSMSQASSRPAPQQSAGRGRGMPQGAGQPQPQQPQQQQRPMPQPQQGGGAR 978
>SYE_AZOSE (Q5NY25) Glutamyl-tRNA synthetase (EC 6.1.1.17) (Glutamate--tRNA| ligase) (GluRS) Length = 465 Score = 29.6 bits (65), Expect = 7.1 Identities = 21/68 (30%), Positives = 31/68 (45%), Gaps = 4/68 (5%) Frame = +1 Query: 229 ERLQRGREEHQG-GDRPSGAGRWRPQ---VPPADRAPLPQMEGSARRTISILAWATATNL 396 E L R REE + G++P GRWRP+ V PA A + + ++AW Sbjct: 105 EELDRMREEQRARGEKPRYDGRWRPEPGKVLPAMPAGVEPVVRFRNPVEGVVAWDDLVKG 164 Query: 397 HI*VRNGK 420 I + N + Sbjct: 165 RIEIANAE 172
>C13AA_CAEEL (Q09653) Putative cytochrome P450 CYP13A10 (EC 1.14.-.-)| Length = 519 Score = 29.3 bits (64), Expect = 9.3 Identities = 25/105 (23%), Positives = 44/105 (41%), Gaps = 10/105 (9%) Frame = +2 Query: 323 PHYLK---WRAQHGEPFLYWHGPQPRICIFEYEMARQILSTKSGHFVKNDAHPTLLALVG 493 P YL+ W +G + Y G + + + ++ RQI + +F +P + G Sbjct: 52 PQYLQIRDWTKLYGPIYGYTEGTIKTLIVSDIDIVRQIFVEQYDNFYGRKLNP----IQG 107 Query: 494 K-------GLGFMEGADWVRHRRIINPVFTIDKLKMMTKTMLDFA 607 L +G W R R I +P F+ + L+ + T+ D A Sbjct: 108 DPEKDERTNLFSAQGFRWKRLRAISSPTFSNNSLRKINVTVEDSA 152
>FBIC_STRAW (Q82GV2) FO synthase (EC 2.5.1.-)| (7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase) Length = 861 Score = 29.3 bits (64), Expect = 9.3 Identities = 25/95 (26%), Positives = 35/95 (36%), Gaps = 4/95 (4%) Frame = +1 Query: 115 GCRHAAVGLRRRAPRMEAVRHEQVVQRTRDPWTLLQVLERLQRGREEHQGG----DRPSG 282 GCR A RR + EQV R + W + V +Q G G D Sbjct: 545 GCRFCAFAQRRTDADAYTLSLEQVADRAQQAWDVGAVEVCMQGGIHPDLPGTAYFDIAKA 604 Query: 283 AGRWRPQVPPADRAPLPQMEGSARRTISILAWATA 387 P + +P+ + G+ R +SI W TA Sbjct: 605 VKERVPGMHVHAFSPMEVVNGATRTGLSIREWLTA 639
>K1849_MOUSE (Q69Z89) Protein KIAA1849| Length = 1099 Score = 29.3 bits (64), Expect = 9.3 Identities = 24/74 (32%), Positives = 37/74 (50%), Gaps = 6/74 (8%) Frame = +1 Query: 58 GLAHGLPCCAPPRSGCSARGCRHAAVGLRRR-APRMEAV---RHEQVVQRTRD-PWTLLQ 222 G A LP CA R G + + CR LR R AP + A R +++ D TLLQ Sbjct: 388 GQAQPLPACALARLGAAPQSCRMCGAVLRARGAPSLPAAVVRRRSLLLEFEPDVEDTLLQ 447 Query: 223 -VLERLQRGREEHQ 261 ++ ++ G ++H+ Sbjct: 448 RIMTLIEPGGDDHK 461
>GAG_AVIMC (P03323) Gag polyprotein [Contains: Core protein p19; Core protein| p10; Core protein p27] Length = 453 Score = 29.3 bits (64), Expect = 9.3 Identities = 15/37 (40%), Positives = 21/37 (56%) Frame = +1 Query: 244 GREEHQGGDRPSGAGRWRPQVPPADRAPLPQMEGSAR 354 G ++ QGGD P GA + R + A +AP P + AR Sbjct: 188 GEQQGQGGDTPRGAEQPRAEPGHAGQAPGPALTDWAR 224
>SNP33_ARATH (Q9S7P9) SNAP25 homologous protein SNAP33 (AtSNAP33)| (Synaptosomal-associated protein SNAP25-like 1) (SNAP-25-like protein 1) (Snap25a) Length = 300 Score = 29.3 bits (64), Expect = 9.3 Identities = 23/89 (25%), Positives = 38/89 (42%) Frame = +1 Query: 106 SARGCRHAAVGLRRRAPRMEAVRHEQVVQRTRDPWTLLQVLERLQRGREEHQGGDRPSGA 285 S +GC A +R A R + H+Q Q TR +++ L RG E+ G + Sbjct: 115 SVQGCLKVAEDIRSDATRTLVMLHDQGEQITRTHHKAVEIDHDLSRG-EKLLGSLGGMFS 173 Query: 286 GRWRPQVPPADRAPLPQMEGSARRTISIL 372 W+P+ P+ + S R ++ L Sbjct: 174 KTWKPKKTRPINGPVVTRDDSPTRRVNHL 202 Database: uniprot_sprot.fasta Posted date: May 25, 2006 5:36 PM Number of letters in database: 80,573,946 Number of sequences in database: 219,361 Lambda K H 0.318 0.135 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 97,051,367 Number of Sequences: 219361 Number of extensions: 2235249 Number of successful extensions: 8121 Number of sequences better than 10.0: 141 Number of HSP's better than 10.0 without gapping: 7435 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 8074 length of database: 80,573,946 effective HSP length: 107 effective length of database: 57,102,319 effective search space used: 5367617986 frameshift window, decay const: 50, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)