ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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| Clone Name | baak4l17 |
|---|---|
| Clone Library Name | barley_pub |
>NLE1_BOVIN (Q58D20) Notchless homolog 1| Length = 485 Score = 227 bits (579), Expect = 2e-59 Identities = 102/143 (71%), Positives = 123/143 (86%) Frame = +1 Query: 4 PXRLVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWN 183 P RLVSGSDDFT+FLW P K+P ARMTGHQ ++N V FSPD + +ASASFDKS+KLW+ Sbjct: 341 PERLVSGSDDFTLFLWSPAEDKKPLARMTGHQALINQVVFSPDSRVIASASFDKSIKLWD 400 Query: 184 GITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVY 363 G TGK++ + RGHVA VYQI+WSADSRLL+SGS DSTLKVWD++A+KL DLPGHADEVY Sbjct: 401 GRTGKYLASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDVKAQKLSTDLPGHADEVY 460 Query: 364 AVDWSPDGEKVVSGGKDRALKLW 432 AVDWSPDG++V SGGKD+ L++W Sbjct: 461 AVDWSPDGQRVASGGKDKCLRIW 483 Score = 85.1 bits (209), Expect = 1e-16 Identities = 51/146 (34%), Positives = 79/146 (54%), Gaps = 6/146 (4%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 L SGS D T+ W+ + ++ P GH+ V + +SPDG+ LAS + + LW+ T Sbjct: 129 LASGSGDTTVRFWDLS-TETPHFTCQGHRHWVLSISWSPDGKKLASGCKNGQILLWDPST 187 Query: 193 GKFV-TAFRGHVADVYQISW-----SADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHAD 354 GK V A GH + +SW + + R + S SKD +++VWD A + ++ L GHA Sbjct: 188 GKQVGRALTGHSKWITALSWEPLHANPECRYVASSSKDGSVRVWDTTAGRCERTLTGHAQ 247 Query: 355 EVYAVDWSPDGEKVVSGGKDRALKLW 432 V + W DG + S +DR +K+W Sbjct: 248 SVTCLRWGGDG-LLYSASQDRTIKVW 272 Score = 72.4 bits (176), Expect = 1e-12 Identities = 41/122 (33%), Positives = 66/122 (54%), Gaps = 6/122 (4%) Frame = +1 Query: 85 MTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSR 264 + GH + V V FSP G++LAS S D +V+ W+ T +GH V ISWS D + Sbjct: 110 LEGHSEAVISVAFSPTGKYLASGSGDTTVRFWDLSTETPHFTCQGHRHWVLSISWSPDGK 169 Query: 265 LLLSGSKDSTLKVWD-IRARKLKQDLPGHADEVYAVDW-----SPDGEKVVSGGKDRALK 426 L SG K+ + +WD +++ + L GH+ + A+ W +P+ V S KD +++ Sbjct: 170 KLASGCKNGQILLWDPSTGKQVGRALTGHSKWITALSWEPLHANPECRYVASSSKDGSVR 229 Query: 427 LW 432 +W Sbjct: 230 VW 231 Score = 72.0 bits (175), Expect = 1e-12 Identities = 42/130 (32%), Positives = 66/130 (50%), Gaps = 5/130 (3%) Frame = +1 Query: 10 RLVSGSDDFTMFLWEPTISKQPKARMTGHQKVV-----NHVYFSPDGQWLASASFDKSVK 174 +L SG + + LW+P+ KQ +TGH K + ++ +P+ +++AS+S D SV+ Sbjct: 170 KLASGCKNGQILLWDPSTGKQVGRALTGHSKWITALSWEPLHANPECRYVASSSKDGSVR 229 Query: 175 LWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHAD 354 +W+ G+ GH V + W D LL S S+D T+KVW L + L GH Sbjct: 230 VWDTTAGRCERTLTGHAQSVTCLRWGGDG-LLYSASQDRTIKVWRAHDGVLCRTLQGHGH 288 Query: 355 EVYAVDWSPD 384 V + S D Sbjct: 289 WVNTMALSTD 298 Score = 58.5 bits (140), Expect = 1e-08 Identities = 26/76 (34%), Positives = 42/76 (55%) Frame = +1 Query: 205 TAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPD 384 ++ GH V +++S + L SGS D+T++ WD+ GH V ++ WSPD Sbjct: 108 SSLEGHSEAVISVAFSPTGKYLASGSGDTTVRFWDLSTETPHFTCQGHRHWVLSISWSPD 167 Query: 385 GEKVVSGGKDRALKLW 432 G+K+ SG K+ + LW Sbjct: 168 GKKLASGCKNGQILLW 183 Score = 50.4 bits (119), Expect = 4e-06 Identities = 45/183 (24%), Positives = 73/183 (39%), Gaps = 43/183 (23%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 + S S D ++ +W+ T + + +TGH + V + + DG L SAS D+++K+W Sbjct: 219 VASSSKDGSVRVWDTTAGRCERT-LTGHAQSVTCLRWGGDGL-LYSASQDRTIKVWRAHD 276 Query: 193 GKFVTAFRGHVADVYQISWSADSRL----------------------------------- 267 G +GH V ++ S D L Sbjct: 277 GVLCRTLQGHGHWVNTMALSTDYALRTGAFEPAEASVNAQDLRGSLQELKERALSRYNLV 336 Query: 268 -------LLSGSKDSTLKVWD-IRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRAL 423 L+SGS D TL +W +K + GH + V +SPD + S D+++ Sbjct: 337 RGQGPERLVSGSDDFTLFLWSPAEDKKPLARMTGHQALINQVVFSPDSRVIASASFDKSI 396 Query: 424 KLW 432 KLW Sbjct: 397 KLW 399
>NLE1_MOUSE (Q8VEJ4) Notchless homolog 1| Length = 484 Score = 226 bits (577), Expect = 3e-59 Identities = 102/143 (71%), Positives = 123/143 (86%) Frame = +1 Query: 4 PXRLVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWN 183 P RLVSGSDDFT+FLW P K+P ARMTGHQ ++N V FSPD + +ASASFDKS+KLW+ Sbjct: 340 PERLVSGSDDFTLFLWSPAEDKKPLARMTGHQALINQVLFSPDSRIVASASFDKSIKLWD 399 Query: 184 GITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVY 363 G TGK++ + RGHVA VYQI+WSADSRLL+SGS DSTLKVWD++A+KL DLPGHADEVY Sbjct: 400 GRTGKYLASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDVKAQKLATDLPGHADEVY 459 Query: 364 AVDWSPDGEKVVSGGKDRALKLW 432 AVDWSPDG++V SGGKD+ L++W Sbjct: 460 AVDWSPDGQRVASGGKDKCLRIW 482 Score = 78.2 bits (191), Expect = 2e-14 Identities = 48/146 (32%), Positives = 76/146 (52%), Gaps = 6/146 (4%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 L SGS D T+ W+ + ++ P GH+ V + +SPDG+ LAS + + LW+ T Sbjct: 128 LASGSGDTTVRFWDLS-TETPHFTCKGHRHWVLSISWSPDGKKLASGCKNGQILLWDPST 186 Query: 193 GKFV-TAFRGHVADVYQISW-----SADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHAD 354 G V GH + +SW + + R + S SKD +++VWD A + ++ L GH Sbjct: 187 GLQVGRTLTGHSKWITGLSWEPLHMNPECRYVASSSKDGSVRVWDTTAGRCERILTGHTQ 246 Query: 355 EVYAVDWSPDGEKVVSGGKDRALKLW 432 V + W DG + S +DR +K+W Sbjct: 247 SVTCLRWGGDG-LLYSASQDRTIKVW 271 Score = 70.1 bits (170), Expect = 5e-12 Identities = 40/122 (32%), Positives = 64/122 (52%), Gaps = 6/122 (4%) Frame = +1 Query: 85 MTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSR 264 + GH + V V FSP G++LAS S D +V+ W+ T +GH V ISWS D + Sbjct: 109 LEGHSEAVISVAFSPTGKYLASGSGDTTVRFWDLSTETPHFTCKGHRHWVLSISWSPDGK 168 Query: 265 LLLSGSKDSTLKVWD-IRARKLKQDLPGHADEVYAVDW-----SPDGEKVVSGGKDRALK 426 L SG K+ + +WD ++ + L GH+ + + W +P+ V S KD +++ Sbjct: 169 KLASGCKNGQILLWDPSTGLQVGRTLTGHSKWITGLSWEPLHMNPECRYVASSSKDGSVR 228 Query: 427 LW 432 +W Sbjct: 229 VW 230 Score = 69.7 bits (169), Expect = 6e-12 Identities = 41/130 (31%), Positives = 65/130 (50%), Gaps = 5/130 (3%) Frame = +1 Query: 10 RLVSGSDDFTMFLWEPTISKQPKARMTGHQKVV-----NHVYFSPDGQWLASASFDKSVK 174 +L SG + + LW+P+ Q +TGH K + ++ +P+ +++AS+S D SV+ Sbjct: 169 KLASGCKNGQILLWDPSTGLQVGRTLTGHSKWITGLSWEPLHMNPECRYVASSSKDGSVR 228 Query: 175 LWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHAD 354 +W+ G+ GH V + W D LL S S+D T+KVW L + L GH Sbjct: 229 VWDTTAGRCERILTGHTQSVTCLRWGGDG-LLYSASQDRTIKVWRAHDGVLCRTLQGHGH 287 Query: 355 EVYAVDWSPD 384 V + S D Sbjct: 288 WVNTMALSTD 297 Score = 58.5 bits (140), Expect = 1e-08 Identities = 26/76 (34%), Positives = 42/76 (55%) Frame = +1 Query: 205 TAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPD 384 ++ GH V +++S + L SGS D+T++ WD+ GH V ++ WSPD Sbjct: 107 SSLEGHSEAVISVAFSPTGKYLASGSGDTTVRFWDLSTETPHFTCKGHRHWVLSISWSPD 166 Query: 385 GEKVVSGGKDRALKLW 432 G+K+ SG K+ + LW Sbjct: 167 GKKLASGCKNGQILLW 182 Score = 49.7 bits (117), Expect = 7e-06 Identities = 46/183 (25%), Positives = 73/183 (39%), Gaps = 43/183 (23%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 + S S D ++ +W+ T + + +TGH + V + + DG L SAS D+++K+W Sbjct: 218 VASSSKDGSVRVWDTTAGRCERI-LTGHTQSVTCLRWGGDGL-LYSASQDRTIKVWRAHD 275 Query: 193 GKFVTAFRGHVADVYQISWSADSRL----------------------------------- 267 G +GH V ++ S D L Sbjct: 276 GVLCRTLQGHGHWVNTMALSTDYALRTGAFEPAEATVNAQDLQGSLKELKERASSRYNLV 335 Query: 268 -------LLSGSKDSTLKVWD-IRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRAL 423 L+SGS D TL +W +K + GH + V +SPD V S D+++ Sbjct: 336 RGQGPERLVSGSDDFTLFLWSPAEDKKPLARMTGHQALINQVLFSPDSRIVASASFDKSI 395 Query: 424 KLW 432 KLW Sbjct: 396 KLW 398
>NLE1_PONPY (Q5RFF8) Notchless homolog 1| Length = 484 Score = 225 bits (574), Expect = 7e-59 Identities = 101/143 (70%), Positives = 122/143 (85%) Frame = +1 Query: 4 PXRLVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWN 183 P RLVSGSDDFT+FLW P K+P RMTGHQ ++N V FSPD + +ASASFDKS+KLW+ Sbjct: 340 PERLVSGSDDFTLFLWSPAEDKKPLTRMTGHQALINQVLFSPDSRIVASASFDKSIKLWD 399 Query: 184 GITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVY 363 G TGK++ + RGHVA VYQI+WSADSRLL+SGS DSTLKVWD++A+KL DLPGHADEVY Sbjct: 400 GRTGKYLASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDVKAQKLAMDLPGHADEVY 459 Query: 364 AVDWSPDGEKVVSGGKDRALKLW 432 AVDWSPDG++V SGGKD+ L++W Sbjct: 460 AVDWSPDGQRVASGGKDKCLRIW 482 Score = 80.5 bits (197), Expect = 4e-15 Identities = 48/146 (32%), Positives = 77/146 (52%), Gaps = 6/146 (4%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 L SGS D T+ W+ + ++ P GH+ V + +SPDG+ LAS + + LW+ T Sbjct: 128 LASGSGDTTVRFWDLS-TETPHFTCKGHRHWVLSISWSPDGKKLASGCKNGQILLWDPST 186 Query: 193 GKFV-TAFRGHVADVYQISW-----SADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHAD 354 GK V GH + +SW + + R + S SKD ++++WD A + ++ L GH Sbjct: 187 GKQVGRTLAGHSKWITGLSWEPLHANPECRYVASSSKDGSVRIWDTTAGRCERILTGHTQ 246 Query: 355 EVYAVDWSPDGEKVVSGGKDRALKLW 432 V + W DG + S +DR +K+W Sbjct: 247 SVTCLRWGGDG-LLYSASQDRTIKVW 271 Score = 72.0 bits (175), Expect = 1e-12 Identities = 40/122 (32%), Positives = 65/122 (53%), Gaps = 6/122 (4%) Frame = +1 Query: 85 MTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSR 264 + GH + V V FSP G++LAS S D +V+ W+ T +GH V ISWS D + Sbjct: 109 LEGHSEAVISVAFSPTGKYLASGSGDTTVRFWDLSTETPHFTCKGHRHWVLSISWSPDGK 168 Query: 265 LLLSGSKDSTLKVWD-IRARKLKQDLPGHADEVYAVDW-----SPDGEKVVSGGKDRALK 426 L SG K+ + +WD +++ + L GH+ + + W +P+ V S KD +++ Sbjct: 169 KLASGCKNGQILLWDPSTGKQVGRTLAGHSKWITGLSWEPLHANPECRYVASSSKDGSVR 228 Query: 427 LW 432 +W Sbjct: 229 IW 230 Score = 70.1 bits (170), Expect = 5e-12 Identities = 41/130 (31%), Positives = 65/130 (50%), Gaps = 5/130 (3%) Frame = +1 Query: 10 RLVSGSDDFTMFLWEPTISKQPKARMTGHQKVV-----NHVYFSPDGQWLASASFDKSVK 174 +L SG + + LW+P+ KQ + GH K + ++ +P+ +++AS+S D SV+ Sbjct: 169 KLASGCKNGQILLWDPSTGKQVGRTLAGHSKWITGLSWEPLHANPECRYVASSSKDGSVR 228 Query: 175 LWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHAD 354 +W+ G+ GH V + W D LL S S+D T+KVW L + L GH Sbjct: 229 IWDTTAGRCERILTGHTQSVTCLRWGGDG-LLYSASQDRTIKVWRAHDGVLCRTLQGHGH 287 Query: 355 EVYAVDWSPD 384 V + S D Sbjct: 288 WVNTMALSTD 297 Score = 58.5 bits (140), Expect = 1e-08 Identities = 26/76 (34%), Positives = 42/76 (55%) Frame = +1 Query: 205 TAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPD 384 ++ GH V +++S + L SGS D+T++ WD+ GH V ++ WSPD Sbjct: 107 SSLEGHSEAVISVAFSPTGKYLASGSGDTTVRFWDLSTETPHFTCKGHRHWVLSISWSPD 166 Query: 385 GEKVVSGGKDRALKLW 432 G+K+ SG K+ + LW Sbjct: 167 GKKLASGCKNGQILLW 182 Score = 50.1 bits (118), Expect = 5e-06 Identities = 46/183 (25%), Positives = 73/183 (39%), Gaps = 43/183 (23%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 + S S D ++ +W+ T + + +TGH + V + + DG L SAS D+++K+W Sbjct: 218 VASSSKDGSVRIWDTTAGRCERI-LTGHTQSVTCLRWGGDGL-LYSASQDRTIKVWRAHD 275 Query: 193 GKFVTAFRGHVADVYQISWSADSRL----------------------------------- 267 G +GH V ++ S D L Sbjct: 276 GVLCRTLQGHGHWVNTMALSTDYALRTGAFEPAEASVNPQDLQGSLQELKERALSRYNLM 335 Query: 268 -------LLSGSKDSTLKVWD-IRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRAL 423 L+SGS D TL +W +K + GH + V +SPD V S D+++ Sbjct: 336 RGQGPERLVSGSDDFTLFLWSPAEDKKPLTRMTGHQALINQVLFSPDSRIVASASFDKSI 395 Query: 424 KLW 432 KLW Sbjct: 396 KLW 398
>NLE1_HUMAN (Q9NVX2) Notchless homolog 1| Length = 484 Score = 225 bits (574), Expect = 7e-59 Identities = 101/143 (70%), Positives = 122/143 (85%) Frame = +1 Query: 4 PXRLVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWN 183 P RLVSGSDDFT+FLW P K+P RMTGHQ ++N V FSPD + +ASASFDKS+KLW+ Sbjct: 340 PERLVSGSDDFTLFLWSPAEDKKPLTRMTGHQALINQVLFSPDSRIVASASFDKSIKLWD 399 Query: 184 GITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVY 363 G TGK++ + RGHVA VYQI+WSADSRLL+SGS DSTLKVWD++A+KL DLPGHADEVY Sbjct: 400 GRTGKYLASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDVKAQKLAMDLPGHADEVY 459 Query: 364 AVDWSPDGEKVVSGGKDRALKLW 432 AVDWSPDG++V SGGKD+ L++W Sbjct: 460 AVDWSPDGQRVASGGKDKCLRIW 482 Score = 80.5 bits (197), Expect = 4e-15 Identities = 48/146 (32%), Positives = 77/146 (52%), Gaps = 6/146 (4%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 L SGS D T+ W+ + ++ P GH+ V + +SPDG+ LAS + + LW+ T Sbjct: 128 LASGSGDTTVRFWDLS-TETPHFTCKGHRHWVLSISWSPDGKKLASGCKNGQILLWDPST 186 Query: 193 GKFV-TAFRGHVADVYQISW-----SADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHAD 354 GK V GH + +SW + + R + S SKD ++++WD A + ++ L GH Sbjct: 187 GKQVGRTLAGHSKWITGLSWEPLHANPECRYVASSSKDGSVRIWDTTAGRCERILTGHTQ 246 Query: 355 EVYAVDWSPDGEKVVSGGKDRALKLW 432 V + W DG + S +DR +K+W Sbjct: 247 SVTCLRWGGDG-LLYSASQDRTIKVW 271 Score = 72.0 bits (175), Expect = 1e-12 Identities = 40/122 (32%), Positives = 65/122 (53%), Gaps = 6/122 (4%) Frame = +1 Query: 85 MTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSR 264 + GH + V V FSP G++LAS S D +V+ W+ T +GH V ISWS D + Sbjct: 109 LEGHSEAVISVAFSPTGKYLASGSGDTTVRFWDLSTETPHFTCKGHRHWVLSISWSPDGK 168 Query: 265 LLLSGSKDSTLKVWD-IRARKLKQDLPGHADEVYAVDW-----SPDGEKVVSGGKDRALK 426 L SG K+ + +WD +++ + L GH+ + + W +P+ V S KD +++ Sbjct: 169 KLASGCKNGQILLWDPSTGKQVGRTLAGHSKWITGLSWEPLHANPECRYVASSSKDGSVR 228 Query: 427 LW 432 +W Sbjct: 229 IW 230 Score = 70.1 bits (170), Expect = 5e-12 Identities = 41/130 (31%), Positives = 65/130 (50%), Gaps = 5/130 (3%) Frame = +1 Query: 10 RLVSGSDDFTMFLWEPTISKQPKARMTGHQKVV-----NHVYFSPDGQWLASASFDKSVK 174 +L SG + + LW+P+ KQ + GH K + ++ +P+ +++AS+S D SV+ Sbjct: 169 KLASGCKNGQILLWDPSTGKQVGRTLAGHSKWITGLSWEPLHANPECRYVASSSKDGSVR 228 Query: 175 LWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHAD 354 +W+ G+ GH V + W D LL S S+D T+KVW L + L GH Sbjct: 229 IWDTTAGRCERILTGHTQSVTCLRWGGDG-LLYSASQDRTIKVWRAHDGVLCRTLQGHGH 287 Query: 355 EVYAVDWSPD 384 V + S D Sbjct: 288 WVNTMALSTD 297 Score = 58.5 bits (140), Expect = 1e-08 Identities = 26/76 (34%), Positives = 42/76 (55%) Frame = +1 Query: 205 TAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPD 384 ++ GH V +++S + L SGS D+T++ WD+ GH V ++ WSPD Sbjct: 107 SSLEGHSEAVISVAFSPTGKYLASGSGDTTVRFWDLSTETPHFTCKGHRHWVLSISWSPD 166 Query: 385 GEKVVSGGKDRALKLW 432 G+K+ SG K+ + LW Sbjct: 167 GKKLASGCKNGQILLW 182 Score = 50.1 bits (118), Expect = 5e-06 Identities = 46/183 (25%), Positives = 73/183 (39%), Gaps = 43/183 (23%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 + S S D ++ +W+ T + + +TGH + V + + DG L SAS D+++K+W Sbjct: 218 VASSSKDGSVRIWDTTAGRCERI-LTGHTQSVTCLRWGGDGL-LYSASQDRTIKVWRAHD 275 Query: 193 GKFVTAFRGHVADVYQISWSADSRL----------------------------------- 267 G +GH V ++ S D L Sbjct: 276 GVLCRTLQGHGHWVNTMALSTDYALRTGAFEPAEASVNPQDLQGSLQELKERALSRYNLV 335 Query: 268 -------LLSGSKDSTLKVWD-IRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRAL 423 L+SGS D TL +W +K + GH + V +SPD V S D+++ Sbjct: 336 RGQGPERLVSGSDDFTLFLWSPAEDKKPLTRMTGHQALINQVLFSPDSRIVASASFDKSI 395 Query: 424 KLW 432 KLW Sbjct: 396 KLW 398
>YCW2_YEAST (P25382) Hypothetical WD-repeat protein YCR072C| Length = 515 Score = 212 bits (540), Expect = 6e-55 Identities = 94/140 (67%), Positives = 117/140 (83%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 +V+ SDD+TMFLW P S +P ARMTGHQK+VNHV FSPDG+++ SASFD S+KLW+G Sbjct: 374 MVTASDDYTMFLWNPLKSTKPIARMTGHQKLVNHVAFSPDGRYIVSASFDNSIKLWDGRD 433 Query: 193 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVD 372 GKF++ FRGHVA VYQ++WS+D RLL+S SKD+TLKVWD+R RKL DLPGH DEVY VD Sbjct: 434 GKFISTFRGHVASVYQVAWSSDCRLLVSCSKDTTLKVWDVRTRKLSVDLPGHKDEVYTVD 493 Query: 373 WSPDGEKVVSGGKDRALKLW 432 WS DG++V SGGKD+ ++LW Sbjct: 494 WSVDGKRVCSGGKDKMVRLW 513 Score = 84.7 bits (208), Expect = 2e-16 Identities = 48/149 (32%), Positives = 79/149 (53%), Gaps = 8/149 (5%) Frame = +1 Query: 10 RLVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGI 189 R+V+G+ D T +W+ ++ P + GH V V +SPDG+ +A+ S D +++LW+ Sbjct: 158 RMVTGAGDNTARIWDCD-TQTPMHTLKGHYNWVLCVSWSPDGEVIATGSMDNTIRLWDPK 216 Query: 190 TGKFV-TAFRGHVADVYQISWS-------ADSRLLLSGSKDSTLKVWDIRARKLKQDLPG 345 +G+ + A RGH + +SW L S SKD T+K+WD +R + + G Sbjct: 217 SGQCLGDALRGHSKWITSLSWEPIHLVKPGSKPRLASSSKDGTIKIWDTVSRVCQYTMSG 276 Query: 346 HADEVYAVDWSPDGEKVVSGGKDRALKLW 432 H + V V W G + SG DR +++W Sbjct: 277 HTNSVSCVKWGGQG-LLYSGSHDRTVRVW 304 Score = 57.8 bits (138), Expect = 2e-08 Identities = 31/125 (24%), Positives = 62/125 (49%), Gaps = 9/125 (7%) Frame = +1 Query: 85 MTGHQKVVNHVYFSPD-GQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADS 261 + GH + F+P + + + D + ++W+ T + +GH V +SWS D Sbjct: 139 IAGHGSTILCSAFAPHTSSRMVTGAGDNTARIWDCDTQTPMHTLKGHYNWVLCVSWSPDG 198 Query: 262 RLLLSGSKDSTLKVWDIRARKLKQD-LPGHADEVYAVDWSP-------DGEKVVSGGKDR 417 ++ +GS D+T+++WD ++ + D L GH+ + ++ W P ++ S KD Sbjct: 199 EVIATGSMDNTIRLWDPKSGQCLGDALRGHSKWITSLSWEPIHLVKPGSKPRLASSSKDG 258 Query: 418 ALKLW 432 +K+W Sbjct: 259 TIKIW 263 Score = 57.0 bits (136), Expect = 4e-08 Identities = 39/132 (29%), Positives = 62/132 (46%), Gaps = 8/132 (6%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSP-------DGQWLASASFDKSV 171 + +GS D T+ LW+P + + GH K + + + P LAS+S D ++ Sbjct: 201 IATGSMDNTIRLWDPKSGQCLGDALRGHSKWITSLSWEPIHLVKPGSKPRLASSSKDGTI 260 Query: 172 KLWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRAR-KLKQDLPGH 348 K+W+ ++ GH V + W LL SGS D T++VWDI ++ + L H Sbjct: 261 KIWDTVSRVCQYTMSGHTNSVSCVKWGGQG-LLYSGSHDRTVRVWDINSQGRCINILKSH 319 Query: 349 ADEVYAVDWSPD 384 A V + S D Sbjct: 320 AHWVNHLSLSTD 331 Score = 53.5 bits (127), Expect = 5e-07 Identities = 24/77 (31%), Positives = 43/77 (55%), Gaps = 1/77 (1%) Frame = +1 Query: 205 TAFRGHVADVYQISWSAD-SRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSP 381 +A GH + + +++ S +++G+ D+T ++WD + L GH + V V WSP Sbjct: 137 SAIAGHGSTILCSAFAPHTSSRMVTGAGDNTARIWDCDTQTPMHTLKGHYNWVLCVSWSP 196 Query: 382 DGEKVVSGGKDRALKLW 432 DGE + +G D ++LW Sbjct: 197 DGEVIATGSMDNTIRLW 213
>Y2124_ANASP (Q8YV57) Hypothetical WD-repeat protein all2124| Length = 1683 Score = 118 bits (296), Expect = 1e-26 Identities = 58/140 (41%), Positives = 89/140 (63%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 + SG D T+ LW+ + K +TGH++ VN+VYFSPDG+ LASAS D S+KLW+ + Sbjct: 1128 IASGGSDKTIKLWQTSDGTLLKT-ITGHEQTVNNVYFSPDGKNLASASSDHSIKLWDTTS 1186 Query: 193 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVD 372 G+ + GH A V + +S D + + +GS+D T+K+W + KL + L GH D V ++ Sbjct: 1187 GQLLMTLTGHSAGVITVRFSPDGQTIAAGSEDKTVKLWHRQDGKLLKTLNGHQDWVNSLS 1246 Query: 373 WSPDGEKVVSGGKDRALKLW 432 +SPDG+ + S D+ +KLW Sbjct: 1247 FSPDGKTLASASADKTIKLW 1266 Score = 117 bits (293), Expect = 3e-26 Identities = 58/140 (41%), Positives = 85/140 (60%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 + S + D T+ +W K K + GH VN V FSPDG+ LASAS D +VKLWN Sbjct: 1419 IASANADKTVKIWRVRDGKALKT-LIGHDNEVNKVNFSPDGKTLASASRDNTVKLWNVSD 1477 Query: 193 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVD 372 GKF +GH +V+ +S+S D +++ S S D T+++WD + L + LP H D VY+V+ Sbjct: 1478 GKFKKTLKGHTDEVFWVSFSPDGKIIASASADKTIRLWDSFSGNLIKSLPAHNDLVYSVN 1537 Query: 373 WSPDGEKVVSGGKDRALKLW 432 ++PDG + S D+ +KLW Sbjct: 1538 FNPDGSMLASTSADKTVKLW 1557 Score = 111 bits (277), Expect = 2e-24 Identities = 60/140 (42%), Positives = 82/140 (58%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 L S S D ++ LW+ T S Q +TGH V V FSPDGQ +A+ S DK+VKLW+ Sbjct: 1170 LASASSDHSIKLWDTT-SGQLLMTLTGHSAGVITVRFSPDGQTIAAGSEDKTVKLWHRQD 1228 Query: 193 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVD 372 GK + GH V +S+S D + L S S D T+K+W I KL + L GH D V+ V+ Sbjct: 1229 GKLLKTLNGHQDWVNSLSFSPDGKTLASASADKTIKLWRIADGKLVKTLKGHNDSVWDVN 1288 Query: 373 WSPDGEKVVSGGKDRALKLW 432 +S DG+ + S +D +KLW Sbjct: 1289 FSSDGKAIASASRDNTIKLW 1308 Score = 109 bits (272), Expect = 7e-24 Identities = 55/140 (39%), Positives = 85/140 (60%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 + +GS+D T+ LW K K + GHQ VN + FSPDG+ LASAS DK++KLW Sbjct: 1212 IAAGSEDKTVKLWHRQDGKLLKT-LNGHQDWVNSLSFSPDGKTLASASADKTIKLWRIAD 1270 Query: 193 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVD 372 GK V +GH V+ +++S+D + + S S+D+T+K+W+ +L + GH+ VYAV+ Sbjct: 1271 GKLVKTLKGHNDSVWDVNFSSDGKAIASASRDNTIKLWNRHGIEL-ETFTGHSGGVYAVN 1329 Query: 373 WSPDGEKVVSGGKDRALKLW 432 + PD + S D ++LW Sbjct: 1330 FLPDSNIIASASLDNTIRLW 1349 Score = 100 bits (250), Expect = 3e-21 Identities = 52/140 (37%), Positives = 77/140 (55%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 + SGS D T+ LW + + GH+ V V FSPDGQ +AS DK++KLW Sbjct: 1087 IASGSLDKTIKLWSR--DGRLFRTLNGHEDAVYSVSFSPDGQTIASGGSDKTIKLWQTSD 1144 Query: 193 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVD 372 G + GH V + +S D + L S S D ++K+WD + +L L GH+ V V Sbjct: 1145 GTLLKTITGHEQTVNNVYFSPDGKNLASASSDHSIKLWDTTSGQLLMTLTGHSAGVITVR 1204 Query: 373 WSPDGEKVVSGGKDRALKLW 432 +SPDG+ + +G +D+ +KLW Sbjct: 1205 FSPDGQTIAAGSEDKTVKLW 1224 Score = 100 bits (248), Expect = 4e-21 Identities = 51/140 (36%), Positives = 79/140 (56%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 L S S D T+ LW + K K + GH V V FSPDG+ +ASAS DK+++LW+ + Sbjct: 1461 LASASRDNTVKLWNVSDGKFKKT-LKGHTDEVFWVSFSPDGKIIASASADKTIRLWDSFS 1519 Query: 193 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVD 372 G + + H VY ++++ D +L S S D T+K+W L GH++ VY+ Sbjct: 1520 GNLIKSLPAHNDLVYSVNFNPDGSMLASTSADKTVKLWRSHDGHLLHTFSGHSNVVYSSS 1579 Query: 373 WSPDGEKVVSGGKDRALKLW 432 +SPDG + S +D+ +K+W Sbjct: 1580 FSPDGRYIASASEDKTVKIW 1599 Score = 98.2 bits (243), Expect = 2e-20 Identities = 55/140 (39%), Positives = 75/140 (53%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 + S S D T+ LW+ K+ + H +V V F+PDG LAS S DK+VKLW Sbjct: 1503 IASASADKTIRLWDSFSGNLIKS-LPAHNDLVYSVNFNPDGSMLASTSADKTVKLWRSHD 1561 Query: 193 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVD 372 G + F GH VY S+S D R + S S+D T+K+W I L LP H V + Sbjct: 1562 GHLLHTFSGHSNVVYSSSFSPDGRYIASASEDKTVKIWQIDGH-LLTTLPQHQAGVMSAI 1620 Query: 373 WSPDGEKVVSGGKDRALKLW 432 +SPDG+ ++SG D K+W Sbjct: 1621 FSPDGKTLISGSLDTTTKIW 1640 Score = 97.4 bits (241), Expect = 3e-20 Identities = 43/111 (38%), Positives = 71/111 (63%) Frame = +1 Query: 100 KVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLLLSG 279 K + + F+P G +ASA+ DK+VK+W GK + GH +V ++++S D + L S Sbjct: 1405 KAIYGISFTPQGDLIASANADKTVKIWRVRDGKALKTLIGHDNEVNKVNFSPDGKTLASA 1464 Query: 280 SKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 S+D+T+K+W++ K K+ L GH DEV+ V +SPDG+ + S D+ ++LW Sbjct: 1465 SRDNTVKLWNVSDGKFKKTLKGHTDEVFWVSFSPDGKIIASASADKTIRLW 1515 Score = 91.7 bits (226), Expect = 2e-18 Identities = 46/129 (35%), Positives = 69/129 (53%) Frame = +1 Query: 46 LWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHV 225 L + Q + R+ GH+ V + S DGQ +AS S DK++KLW+ G+ GH Sbjct: 1055 LQQALFEMQERNRLEGHKDGVISISISRDGQTIASGSLDKTIKLWSR-DGRLFRTLNGHE 1113 Query: 226 ADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSG 405 VY +S+S D + + SG D T+K+W L + + GH V V +SPDG+ + S Sbjct: 1114 DAVYSVSFSPDGQTIASGGSDKTIKLWQTSDGTLLKTITGHEQTVNNVYFSPDGKNLASA 1173 Query: 406 GKDRALKLW 432 D ++KLW Sbjct: 1174 SSDHSIKLW 1182 Score = 70.5 bits (171), Expect = 4e-12 Identities = 42/106 (39%), Positives = 59/106 (55%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 L S S D T+ LW + +GH VV FSPDG+++ASAS DK+VK+W I Sbjct: 1545 LASTSADKTVKLWR-SHDGHLLHTFSGHSNVVYSSSFSPDGRYIASASEDKTVKIWQ-ID 1602 Query: 193 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLK 330 G +T H A V +S D + L+SGS D+T K+W +++ K Sbjct: 1603 GHLLTTLPQHQAGVMSAIFSPDGKTLISGSLDTTTKIWRFDSQQAK 1648 Score = 67.8 bits (164), Expect = 2e-11 Identities = 49/181 (27%), Positives = 77/181 (42%), Gaps = 41/181 (22%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 L S S D T+ LW K K + GH V V FS DG+ +ASAS D ++KLWN Sbjct: 1254 LASASADKTIKLWRIADGKLVKT-LKGHNDSVWDVNFSSDGKAIASASRDNTIKLWNR-H 1311 Query: 193 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDS--------------------------- 291 G + F GH VY +++ DS ++ S S D+ Sbjct: 1312 GIELETFTGHSGGVYAVNFLPDSNIIASASLDNTIRLWQRPLISPLEVLAGNSGVYAVSF 1371 Query: 292 --------------TLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKL 429 +++W + L + LPG+ +Y + ++P G+ + S D+ +K+ Sbjct: 1372 LHDGSIIATAGADGNIQLWHSQDGSLLKTLPGN-KAIYGISFTPQGDLIASANADKTVKI 1430 Query: 430 W 432 W Sbjct: 1431 W 1431
>WDS_DROME (Q9V3J8) Protein will die slowly| Length = 361 Score = 117 bits (293), Expect = 3e-26 Identities = 51/119 (42%), Positives = 77/119 (64%) Frame = +1 Query: 76 KARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSA 255 K + GH K V+ V FSP+G+WLAS+S DK +K+W GKF GH + ++WS+ Sbjct: 65 KFTLAGHTKAVSAVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSS 124 Query: 256 DSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 DSRLL+SGS D TLKVW++ K + L GH++ V+ +++P +VSG D ++++W Sbjct: 125 DSRLLVSGSDDKTLKVWELSTGKSLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIW 183 Score = 84.0 bits (206), Expect = 3e-16 Identities = 48/141 (34%), Positives = 75/141 (53%), Gaps = 1/141 (0%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 LVSGSDD T+ +WE + K K + GH V F+P + S SFD+SV++W+ T Sbjct: 129 LVSGSDDKTLKVWELSTGKSLKT-LKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVRT 187 Query: 193 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARK-LKQDLPGHADEVYAV 369 GK + H V + ++ D L++S S D ++WD + + LK + V V Sbjct: 188 GKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPVSFV 247 Query: 370 DWSPDGEKVVSGGKDRALKLW 432 +SP+G+ +++ D LKLW Sbjct: 248 KFSPNGKYILAATLDNTLKLW 268 Score = 73.9 bits (180), Expect = 3e-13 Identities = 40/145 (27%), Positives = 76/145 (52%), Gaps = 5/145 (3%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 +VS S D +W+ + K + V+ V FSP+G+++ +A+ D ++KLW+ Sbjct: 213 IVSSSYDGLCRIWDTASGQCLKTLIDDDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSK 272 Query: 193 GKFVTAFRGHVADVYQISWS---ADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVY 363 GK + + GH + Y I + + ++SGS+D+ + +W+++++++ Q L GH D V Sbjct: 273 GKCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNMVYIWNLQSKEVVQKLQGHTDTVL 332 Query: 364 AVDWSPDGEKVVSGG--KDRALKLW 432 P + S D+ +KLW Sbjct: 333 CTACHPTENIIASAALENDKTIKLW 357 Score = 35.8 bits (81), Expect = 0.10 Identities = 16/36 (44%), Positives = 22/36 (61%) Frame = +1 Query: 325 LKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 LK L GH V AV +SP+GE + S D+ +K+W Sbjct: 64 LKFTLAGHTKAVSAVKFSPNGEWLASSSADKLIKIW 99
>WDR5_MOUSE (P61965) WD-repeat protein 5 (BMP2-induced 3-kb gene protein)| (WD-repeat protein BIG-3) Length = 334 Score = 115 bits (289), Expect = 8e-26 Identities = 49/119 (41%), Positives = 76/119 (63%) Frame = +1 Query: 76 KARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSA 255 K + GH K V+ V FSP+G+WLAS+S DK +K+W GKF GH + ++WS+ Sbjct: 38 KFTLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSS 97 Query: 256 DSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 DS LL+S S D TLK+WD+ + K + L GH++ V+ +++P +VSG D ++++W Sbjct: 98 DSNLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIW 156 Score = 91.3 bits (225), Expect = 2e-18 Identities = 47/140 (33%), Positives = 81/140 (57%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 L S S D + +W K K ++GH+ ++ V +S D L SAS DK++K+W+ + Sbjct: 60 LASSSADKLIKIWGAYDGKFEKT-ISGHKLGISDVAWSSDSNLLVSASDDKTLKIWDVSS 118 Query: 193 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVD 372 GK + +GH V+ +++ S L++SGS D ++++WD++ K + LP H+D V AV Sbjct: 119 GKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSAVH 178 Query: 373 WSPDGEKVVSGGKDRALKLW 432 ++ DG +VS D ++W Sbjct: 179 FNRDGSLIVSSSYDGLCRIW 198 Score = 79.7 bits (195), Expect = 6e-15 Identities = 46/141 (32%), Positives = 74/141 (52%), Gaps = 1/141 (0%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 LVS SDD T+ +W+ + K K + GH V F+P + S SFD+SV++W+ T Sbjct: 102 LVSASDDKTLKIWDVSSGKCLKT-LKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKT 160 Query: 193 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARK-LKQDLPGHADEVYAV 369 GK + H V + ++ D L++S S D ++WD + + LK + V V Sbjct: 161 GKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPVSFV 220 Query: 370 DWSPDGEKVVSGGKDRALKLW 432 +SP+G+ +++ D LKLW Sbjct: 221 KFSPNGKYILAATLDNTLKLW 241 Score = 73.9 bits (180), Expect = 3e-13 Identities = 40/145 (27%), Positives = 76/145 (52%), Gaps = 5/145 (3%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 +VS S D +W+ + K + V+ V FSP+G+++ +A+ D ++KLW+ Sbjct: 186 IVSSSYDGLCRIWDTASGQCLKTLIDDDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSK 245 Query: 193 GKFVTAFRGHVADVYQISWS---ADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVY 363 GK + + GH + Y I + + ++SGS+D+ + +W+++ +++ Q L GH D V Sbjct: 246 GKCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQGHTDVVI 305 Query: 364 AVDWSPDGEKVVSGG--KDRALKLW 432 + P + S D+ +KLW Sbjct: 306 STACHPTENIIASAALENDKTIKLW 330 Score = 34.7 bits (78), Expect = 0.23 Identities = 15/36 (41%), Positives = 22/36 (61%) Frame = +1 Query: 325 LKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 LK L GH V +V +SP+GE + S D+ +K+W Sbjct: 37 LKFTLAGHTKAVSSVKFSPNGEWLASSSADKLIKIW 72
>WDR5_HUMAN (P61964) WD-repeat protein 5 (BMP2-induced 3-kb gene protein)| Length = 334 Score = 115 bits (289), Expect = 8e-26 Identities = 49/119 (41%), Positives = 76/119 (63%) Frame = +1 Query: 76 KARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSA 255 K + GH K V+ V FSP+G+WLAS+S DK +K+W GKF GH + ++WS+ Sbjct: 38 KFTLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSS 97 Query: 256 DSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 DS LL+S S D TLK+WD+ + K + L GH++ V+ +++P +VSG D ++++W Sbjct: 98 DSNLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIW 156 Score = 91.3 bits (225), Expect = 2e-18 Identities = 47/140 (33%), Positives = 81/140 (57%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 L S S D + +W K K ++GH+ ++ V +S D L SAS DK++K+W+ + Sbjct: 60 LASSSADKLIKIWGAYDGKFEKT-ISGHKLGISDVAWSSDSNLLVSASDDKTLKIWDVSS 118 Query: 193 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVD 372 GK + +GH V+ +++ S L++SGS D ++++WD++ K + LP H+D V AV Sbjct: 119 GKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSAVH 178 Query: 373 WSPDGEKVVSGGKDRALKLW 432 ++ DG +VS D ++W Sbjct: 179 FNRDGSLIVSSSYDGLCRIW 198 Score = 79.7 bits (195), Expect = 6e-15 Identities = 46/141 (32%), Positives = 74/141 (52%), Gaps = 1/141 (0%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 LVS SDD T+ +W+ + K K + GH V F+P + S SFD+SV++W+ T Sbjct: 102 LVSASDDKTLKIWDVSSGKCLKT-LKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKT 160 Query: 193 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARK-LKQDLPGHADEVYAV 369 GK + H V + ++ D L++S S D ++WD + + LK + V V Sbjct: 161 GKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPVSFV 220 Query: 370 DWSPDGEKVVSGGKDRALKLW 432 +SP+G+ +++ D LKLW Sbjct: 221 KFSPNGKYILAATLDNTLKLW 241 Score = 73.9 bits (180), Expect = 3e-13 Identities = 40/145 (27%), Positives = 76/145 (52%), Gaps = 5/145 (3%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 +VS S D +W+ + K + V+ V FSP+G+++ +A+ D ++KLW+ Sbjct: 186 IVSSSYDGLCRIWDTASGQCLKTLIDDDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSK 245 Query: 193 GKFVTAFRGHVADVYQISWS---ADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVY 363 GK + + GH + Y I + + ++SGS+D+ + +W+++ +++ Q L GH D V Sbjct: 246 GKCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQGHTDVVI 305 Query: 364 AVDWSPDGEKVVSGG--KDRALKLW 432 + P + S D+ +KLW Sbjct: 306 STACHPTENIIASAALENDKTIKLW 330 Score = 34.7 bits (78), Expect = 0.23 Identities = 15/36 (41%), Positives = 22/36 (61%) Frame = +1 Query: 325 LKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 LK L GH V +V +SP+GE + S D+ +K+W Sbjct: 37 LKFTLAGHTKAVSSVKFSPNGEWLASSSADKLIKIW 72
>HETE1_PODAN (Q00808) Vegetatible incompatibility protein HET-E-1| Length = 1356 Score = 113 bits (283), Expect = 4e-25 Identities = 56/141 (39%), Positives = 84/141 (59%) Frame = +1 Query: 10 RLVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGI 189 R+ SGSDD T+ +W+ T S + GH V V FSPDGQ +AS S D ++K+W+ + Sbjct: 1023 RVASGSDDKTIKIWD-TASGTCTQTLEGHGGWVQSVVFSPDGQRVASGSDDHTIKIWDAV 1081 Query: 190 TGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAV 369 +G GH V+ +++S D + + SGS D T+K+WD + Q L GH V++V Sbjct: 1082 SGTCTQTLEGHGDSVWSVAFSPDGQRVASGSIDGTIKIWDAASGTCTQTLEGHGGWVHSV 1141 Query: 370 DWSPDGEKVVSGGKDRALKLW 432 +SPDG++V SG D +K+W Sbjct: 1142 AFSPDGQRVASGSIDGTIKIW 1162 Score = 113 bits (283), Expect = 4e-25 Identities = 56/141 (39%), Positives = 82/141 (58%) Frame = +1 Query: 10 RLVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGI 189 R+ SGSDD T+ +W+ S + GH V V FSPDGQ +AS S DK++K+W+ Sbjct: 939 RVASGSDDHTIKIWDAA-SGTCTQTLEGHGSSVLSVAFSPDGQRVASGSGDKTIKIWDTA 997 Query: 190 TGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAV 369 +G GH V+ +++S D + + SGS D T+K+WD + Q L GH V +V Sbjct: 998 SGTCTQTLEGHGGSVWSVAFSPDGQRVASGSDDKTIKIWDTASGTCTQTLEGHGGWVQSV 1057 Query: 370 DWSPDGEKVVSGGKDRALKLW 432 +SPDG++V SG D +K+W Sbjct: 1058 VFSPDGQRVASGSDDHTIKIW 1078 Score = 113 bits (283), Expect = 4e-25 Identities = 55/141 (39%), Positives = 83/141 (58%) Frame = +1 Query: 10 RLVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGI 189 R+ SGSDD T+ +W+ S + GH V V FSPDGQ +AS S D ++K+W+ Sbjct: 897 RVASGSDDKTIKIWDAA-SGTCTQTLEGHGGRVQSVAFSPDGQRVASGSDDHTIKIWDAA 955 Query: 190 TGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAV 369 +G GH + V +++S D + + SGS D T+K+WD + Q L GH V++V Sbjct: 956 SGTCTQTLEGHGSSVLSVAFSPDGQRVASGSGDKTIKIWDTASGTCTQTLEGHGGSVWSV 1015 Query: 370 DWSPDGEKVVSGGKDRALKLW 432 +SPDG++V SG D+ +K+W Sbjct: 1016 AFSPDGQRVASGSDDKTIKIW 1036 Score = 112 bits (281), Expect = 7e-25 Identities = 55/141 (39%), Positives = 83/141 (58%) Frame = +1 Query: 10 RLVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGI 189 R+ SGSDD T+ +W+ +S + GH V V FSPDGQ +AS S D ++K+W+ Sbjct: 1065 RVASGSDDHTIKIWD-AVSGTCTQTLEGHGDSVWSVAFSPDGQRVASGSIDGTIKIWDAA 1123 Query: 190 TGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAV 369 +G GH V+ +++S D + + SGS D T+K+WD + Q L GH V +V Sbjct: 1124 SGTCTQTLEGHGGWVHSVAFSPDGQRVASGSIDGTIKIWDAASGTCTQTLEGHGGWVQSV 1183 Query: 370 DWSPDGEKVVSGGKDRALKLW 432 +SPDG++V SG D+ +K+W Sbjct: 1184 AFSPDGQRVASGSSDKTIKIW 1204 Score = 110 bits (275), Expect = 3e-24 Identities = 55/141 (39%), Positives = 82/141 (58%) Frame = +1 Query: 10 RLVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGI 189 R+ SGSDD T+ +W+ T S + GH V V FSPD + +AS S DK++K+W+ Sbjct: 855 RVASGSDDKTIKIWD-TASGTGTQTLEGHGGSVWSVAFSPDRERVASGSDDKTIKIWDAA 913 Query: 190 TGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAV 369 +G GH V +++S D + + SGS D T+K+WD + Q L GH V +V Sbjct: 914 SGTCTQTLEGHGGRVQSVAFSPDGQRVASGSDDHTIKIWDAASGTCTQTLEGHGSSVLSV 973 Query: 370 DWSPDGEKVVSGGKDRALKLW 432 +SPDG++V SG D+ +K+W Sbjct: 974 AFSPDGQRVASGSGDKTIKIW 994 Score = 109 bits (273), Expect = 6e-24 Identities = 57/141 (40%), Positives = 82/141 (58%) Frame = +1 Query: 10 RLVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGI 189 R+ SGS D T+ +W+ T S + GH V V FSPDGQ +AS S DK++K+W+ Sbjct: 981 RVASGSGDKTIKIWD-TASGTCTQTLEGHGGSVWSVAFSPDGQRVASGSDDKTIKIWDTA 1039 Query: 190 TGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAV 369 +G GH V + +S D + + SGS D T+K+WD + Q L GH D V++V Sbjct: 1040 SGTCTQTLEGHGGWVQSVVFSPDGQRVASGSDDHTIKIWDAVSGTCTQTLEGHGDSVWSV 1099 Query: 370 DWSPDGEKVVSGGKDRALKLW 432 +SPDG++V SG D +K+W Sbjct: 1100 AFSPDGQRVASGSIDGTIKIW 1120 Score = 107 bits (267), Expect = 3e-23 Identities = 54/141 (38%), Positives = 80/141 (56%) Frame = +1 Query: 10 RLVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGI 189 R+ SGS D T+ +W+ S + GH V+ V FSPDGQ +AS S D ++K+W+ Sbjct: 1107 RVASGSIDGTIKIWDAA-SGTCTQTLEGHGGWVHSVAFSPDGQRVASGSIDGTIKIWDAA 1165 Query: 190 TGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAV 369 +G GH V +++S D + + SGS D T+K+WD + Q L GH V +V Sbjct: 1166 SGTCTQTLEGHGGWVQSVAFSPDGQRVASGSSDKTIKIWDTASGTCTQTLEGHGGWVQSV 1225 Query: 370 DWSPDGEKVVSGGKDRALKLW 432 +SPDG++V SG D +K+W Sbjct: 1226 AFSPDGQRVASGSSDNTIKIW 1246 Score = 99.0 bits (245), Expect = 1e-20 Identities = 46/116 (39%), Positives = 67/116 (57%) Frame = +1 Query: 85 MTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSR 264 + GH V V FS DGQ +AS S DK++K+W+ +G GH V+ +++S D Sbjct: 837 LEGHGSSVLSVAFSADGQRVASGSDDKTIKIWDTASGTGTQTLEGHGGSVWSVAFSPDRE 896 Query: 265 LLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 + SGS D T+K+WD + Q L GH V +V +SPDG++V SG D +K+W Sbjct: 897 RVASGSDDKTIKIWDAASGTCTQTLEGHGGRVQSVAFSPDGQRVASGSDDHTIKIW 952 Score = 76.6 bits (187), Expect = 5e-14 Identities = 41/110 (37%), Positives = 61/110 (55%) Frame = +1 Query: 10 RLVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGI 189 R+ SGS D T+ +W+ S + GH V V FSPDGQ +AS S DK++K+W+ Sbjct: 1149 RVASGSIDGTIKIWDAA-SGTCTQTLEGHGGWVQSVAFSPDGQRVASGSSDKTIKIWDTA 1207 Query: 190 TGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDL 339 +G GH V +++S D + + SGS D+T+K+WD + Q L Sbjct: 1208 SGTCTQTLEGHGGWVQSVAFSPDGQRVASGSSDNTIKIWDTASGTCTQTL 1257 Score = 41.2 bits (95), Expect = 0.002 Identities = 18/48 (37%), Positives = 27/48 (56%) Frame = +1 Query: 289 STLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 ST+ V + Q L GH V +V +S DG++V SG D+ +K+W Sbjct: 821 STISVVEAEWNACTQTLEGHGSSVLSVAFSADGQRVASGSDDKTIKIW 868
>YY46_ANASP (Q8YRI1) Hypothetical WD-repeat protein alr3466| Length = 1526 Score = 108 bits (270), Expect = 1e-23 Identities = 57/140 (40%), Positives = 81/140 (57%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 L SGS D T+ LWE SK GH VN V F+PDG LAS S DK+V+LW+ + Sbjct: 1215 LASGSSDQTVRLWEINSSKC-LCTFQGHTSWVNSVVFNPDGSMLASGSSDKTVRLWDISS 1273 Query: 193 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVD 372 K + F+GH V ++++ D +L SGS D T+++W+I + K GH V +V Sbjct: 1274 SKCLHTFQGHTNWVNSVAFNPDGSMLASGSGDQTVRLWEISSSKCLHTFQGHTSWVSSVT 1333 Query: 373 WSPDGEKVVSGGKDRALKLW 432 +SPDG + SG D+ ++LW Sbjct: 1334 FSPDGTMLASGSDDQTVRLW 1353 Score = 105 bits (263), Expect = 8e-23 Identities = 55/140 (39%), Positives = 83/140 (59%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 L SGS D T+ LW+ + SK + GH VN V F+PDG LAS S D++V+LW + Sbjct: 1173 LASGSGDQTVRLWDISSSKCLYI-LQGHTSWVNSVVFNPDGSTLASGSSDQTVRLWEINS 1231 Query: 193 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVD 372 K + F+GH + V + ++ D +L SGS D T+++WDI + K GH + V +V Sbjct: 1232 SKCLCTFQGHTSWVNSVVFNPDGSMLASGSSDKTVRLWDISSSKCLHTFQGHTNWVNSVA 1291 Query: 373 WSPDGEKVVSGGKDRALKLW 432 ++PDG + SG D+ ++LW Sbjct: 1292 FNPDGSMLASGSGDQTVRLW 1311 Score = 101 bits (252), Expect = 2e-21 Identities = 57/140 (40%), Positives = 82/140 (58%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 L SGS D T+ LWE + SK GH V+ V FSPDG LAS S D++V+LW+ + Sbjct: 1299 LASGSGDQTVRLWEISSSKCLHT-FQGHTSWVSSVTFSPDGTMLASGSDDQTVRLWSISS 1357 Query: 193 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVD 372 G+ + F GH V + +S D +L SGS D T+++W I + K L GH + V ++ Sbjct: 1358 GECLYTFLGHTNWVGSVIFSPDGAILASGSGDQTVRLWSISSGKCLYTLQGHNNWVGSIV 1417 Query: 373 WSPDGEKVVSGGKDRALKLW 432 +SPDG + SG D+ ++LW Sbjct: 1418 FSPDGTLLASGSDDQTVRLW 1437 Score = 101 bits (252), Expect = 2e-21 Identities = 55/140 (39%), Positives = 82/140 (58%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 L SGS D T+ LW+ + SK GH VN V F+PDG LAS S D++V+LW + Sbjct: 1257 LASGSSDKTVRLWDISSSKCLHT-FQGHTNWVNSVAFNPDGSMLASGSGDQTVRLWEISS 1315 Query: 193 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVD 372 K + F+GH + V +++S D +L SGS D T+++W I + + GH + V +V Sbjct: 1316 SKCLHTFQGHTSWVSSVTFSPDGTMLASGSDDQTVRLWSISSGECLYTFLGHTNWVGSVI 1375 Query: 373 WSPDGEKVVSGGKDRALKLW 432 +SPDG + SG D+ ++LW Sbjct: 1376 FSPDGAILASGSGDQTVRLW 1395 Score = 99.8 bits (247), Expect = 6e-21 Identities = 53/140 (37%), Positives = 82/140 (58%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 L SGSDD T+ LW+ + S Q GH V V FSP+ LAS S D++V+LW+ + Sbjct: 921 LASGSDDQTVRLWDIS-SGQCLKTFKGHTSRVRSVVFSPNSLMLASGSSDQTVRLWDISS 979 Query: 193 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVD 372 G+ + F+GH VY ++++ D +L +GS D T+++WDI + + GH V +V Sbjct: 980 GECLYIFQGHTGWVYSVAFNLDGSMLATGSGDQTVRLWDISSSQCFYIFQGHTSCVRSVV 1039 Query: 373 WSPDGEKVVSGGKDRALKLW 432 +S DG + SG D+ ++LW Sbjct: 1040 FSSDGAMLASGSDDQTVRLW 1059 Score = 99.0 bits (245), Expect = 1e-20 Identities = 58/140 (41%), Positives = 80/140 (57%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 L SGSDD T+ LW + S + GH V V FSPDG LAS S D++V+LW+ + Sbjct: 1341 LASGSDDQTVRLWSIS-SGECLYTFLGHTNWVGSVIFSPDGAILASGSGDQTVRLWSISS 1399 Query: 193 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVD 372 GK + +GH V I +S D LL SGS D T+++W+I + + L GH + V +V Sbjct: 1400 GKCLYTLQGHNNWVGSIVFSPDGTLLASGSDDQTVRLWNISSGECLYTLHGHINSVRSVA 1459 Query: 373 WSPDGEKVVSGGKDRALKLW 432 +S DG + SG D +KLW Sbjct: 1460 FSSDGLILASGSDDETIKLW 1479 Score = 98.6 bits (244), Expect = 1e-20 Identities = 52/140 (37%), Positives = 81/140 (57%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 L +GS D + LW+ + SK+ + GH VN V FSPDG LAS S D++V+LW+ + Sbjct: 1131 LANGSSDQIVRLWDIS-SKKCLYTLQGHTNWVNAVAFSPDGATLASGSGDQTVRLWDISS 1189 Query: 193 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVD 372 K + +GH + V + ++ D L SGS D T+++W+I + K GH V +V Sbjct: 1190 SKCLYILQGHTSWVNSVVFNPDGSTLASGSSDQTVRLWEINSSKCLCTFQGHTSWVNSVV 1249 Query: 373 WSPDGEKVVSGGKDRALKLW 432 ++PDG + SG D+ ++LW Sbjct: 1250 FNPDGSMLASGSSDKTVRLW 1269 Score = 96.3 bits (238), Expect = 6e-20 Identities = 53/140 (37%), Positives = 80/140 (57%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 L SGSDD T+ LW+ + S + GH V V FSPDG LAS D+ V+LW+ + Sbjct: 1047 LASGSDDQTVRLWDIS-SGNCLYTLQGHTSCVRSVVFSPDGAMLASGGDDQIVRLWDISS 1105 Query: 193 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVD 372 G + +G+ + V + +S + L +GS D +++WDI ++K L GH + V AV Sbjct: 1106 GNCLYTLQGYTSWVRFLVFSPNGVTLANGSSDQIVRLWDISSKKCLYTLQGHTNWVNAVA 1165 Query: 373 WSPDGEKVVSGGKDRALKLW 432 +SPDG + SG D+ ++LW Sbjct: 1166 FSPDGATLASGSGDQTVRLW 1185 Score = 95.1 bits (235), Expect = 1e-19 Identities = 53/140 (37%), Positives = 81/140 (57%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 L SGS D T+ LW+ + S + GH V V F+ DG LA+ S D++V+LW+ + Sbjct: 963 LASGSSDQTVRLWDIS-SGECLYIFQGHTGWVYSVAFNLDGSMLATGSGDQTVRLWDISS 1021 Query: 193 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVD 372 + F+GH + V + +S+D +L SGS D T+++WDI + L GH V +V Sbjct: 1022 SQCFYIFQGHTSCVRSVVFSSDGAMLASGSDDQTVRLWDISSGNCLYTLQGHTSCVRSVV 1081 Query: 373 WSPDGEKVVSGGKDRALKLW 432 +SPDG + SGG D+ ++LW Sbjct: 1082 FSPDGAMLASGGDDQIVRLW 1101 Score = 93.2 bits (230), Expect = 5e-19 Identities = 47/128 (36%), Positives = 75/128 (58%) Frame = +1 Query: 49 WEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVA 228 WE K+ GH VN V FS DG+ LAS S D++V+LW+ +G+ + F+GH + Sbjct: 891 WEAATGKE-LLTCKGHNSWVNSVGFSQDGKMLASGSDDQTVRLWDISSGQCLKTFKGHTS 949 Query: 229 DVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGG 408 V + +S +S +L SGS D T+++WDI + + GH VY+V ++ DG + +G Sbjct: 950 RVRSVVFSPNSLMLASGSSDQTVRLWDISSGECLYIFQGHTGWVYSVAFNLDGSMLATGS 1009 Query: 409 KDRALKLW 432 D+ ++LW Sbjct: 1010 GDQTVRLW 1017 Score = 90.1 bits (222), Expect = 5e-18 Identities = 50/140 (35%), Positives = 78/140 (55%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 L SG DD + LW+ + S + G+ V + FSP+G LA+ S D+ V+LW+ + Sbjct: 1089 LASGGDDQIVRLWDIS-SGNCLYTLQGYTSWVRFLVFSPNGVTLANGSSDQIVRLWDISS 1147 Query: 193 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVD 372 K + +GH V +++S D L SGS D T+++WDI + K L GH V +V Sbjct: 1148 KKCLYTLQGHTNWVNAVAFSPDGATLASGSGDQTVRLWDISSSKCLYILQGHTSWVNSVV 1207 Query: 373 WSPDGEKVVSGGKDRALKLW 432 ++PDG + SG D+ ++LW Sbjct: 1208 FNPDGSTLASGSSDQTVRLW 1227 Score = 87.0 bits (214), Expect = 4e-17 Identities = 48/140 (34%), Positives = 76/140 (54%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 L +GS D T+ LW+ + S Q GH V V FS DG LAS S D++V+LW+ + Sbjct: 1005 LATGSGDQTVRLWDIS-SSQCFYIFQGHTSCVRSVVFSSDGAMLASGSDDQTVRLWDISS 1063 Query: 193 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVD 372 G + +GH + V + +S D +L SG D +++WDI + L G+ V + Sbjct: 1064 GNCLYTLQGHTSCVRSVVFSPDGAMLASGGDDQIVRLWDISSGNCLYTLQGYTSWVRFLV 1123 Query: 373 WSPDGEKVVSGGKDRALKLW 432 +SP+G + +G D+ ++LW Sbjct: 1124 FSPNGVTLANGSSDQIVRLW 1143 Score = 81.3 bits (199), Expect = 2e-15 Identities = 41/101 (40%), Positives = 61/101 (60%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 L SGS D T+ LW + K + GH V + FSPDG LAS S D++V+LWN + Sbjct: 1383 LASGSGDQTVRLWSISSGKCLYT-LQGHNNWVGSIVFSPDGTLLASGSDDQTVRLWNISS 1441 Query: 193 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIR 315 G+ + GH+ V +++S+D +L SGS D T+K+WD++ Sbjct: 1442 GECLYTLHGHINSVRSVAFSSDGLILASGSDDETIKLWDVK 1482 Score = 79.3 bits (194), Expect = 8e-15 Identities = 37/106 (34%), Positives = 60/106 (56%) Frame = +1 Query: 115 VYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDST 294 V FSPDG+ A+ V+ W TGK + +GH + V + +S D ++L SGS D T Sbjct: 870 VAFSPDGKLFATGDSGGIVRFWEAATGKELLTCKGHNSWVNSVGFSQDGKMLASGSDDQT 929 Query: 295 LKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 +++WDI + + + GH V +V +SP+ + SG D+ ++LW Sbjct: 930 VRLWDISSGQCLKTFKGHTSRVRSVVFSPNSLMLASGSSDQTVRLW 975 Score = 47.0 bits (110), Expect = 4e-05 Identities = 28/68 (41%), Positives = 39/68 (57%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 L SGSDD T+ LW + S + + GH V V FS DG LAS S D+++KLW+ T Sbjct: 1425 LASGSDDQTVRLWNIS-SGECLYTLHGHINSVRSVAFSSDGLILASGSDDETIKLWDVKT 1483 Query: 193 GKFVTAFR 216 G+ + + Sbjct: 1484 GECIKTLK 1491 Score = 43.1 bits (100), Expect = 6e-04 Identities = 20/76 (26%), Positives = 37/76 (48%) Frame = +1 Query: 205 TAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPD 384 + F + V +++S D +L +G ++ W+ K GH V +V +S D Sbjct: 858 SVFTKILGSVLTVAFSPDGKLFATGDSGGIVRFWEAATGKELLTCKGHNSWVNSVGFSQD 917 Query: 385 GEKVVSGGKDRALKLW 432 G+ + SG D+ ++LW Sbjct: 918 GKMLASGSDDQTVRLW 933
>Y2800_ANASP (Q8YTC2) Hypothetical WD-repeat protein alr2800| Length = 1258 Score = 107 bits (267), Expect = 3e-23 Identities = 55/140 (39%), Positives = 86/140 (61%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 L S + D T+ LW+ + K + + H V V FS DGQ LAS S D+++K+WN T Sbjct: 783 LASSAADHTIKLWDVSQGKCLRT-LKSHTGWVRSVAFSADGQTLASGSGDRTIKIWNYHT 841 Query: 193 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVD 372 G+ + + GH VY I++S DS++L+SGS D T+K+WD + + L GH +EV +V Sbjct: 842 GECLKTYIGHTNSVYSIAYSPDSKILVSGSGDRTIKLWDCQTHICIKTLHGHTNEVCSVA 901 Query: 373 WSPDGEKVVSGGKDRALKLW 432 +SPDG+ + D++++LW Sbjct: 902 FSPDGQTLACVSLDQSVRLW 921 Score = 106 bits (265), Expect = 5e-23 Identities = 57/140 (40%), Positives = 82/140 (58%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 LVSGS D T+ LW+ K + GH V V FSPDGQ LA S D+SV+LWN T Sbjct: 867 LVSGSGDRTIKLWDCQTHICIKT-LHGHTNEVCSVAFSPDGQTLACVSLDQSVRLWNCRT 925 Query: 193 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVD 372 G+ + A+ G+ +++S D ++L SGS D T+K+WD + K L GH D +Y + Sbjct: 926 GQCLKAWYGNTDWALPVAFSPDRQILASGSNDKTVKLWDWQTGKYISSLEGHTDFIYGIA 985 Query: 373 WSPDGEKVVSGGKDRALKLW 432 +SPD + + S D +++LW Sbjct: 986 FSPDSQTLASASTDSSVRLW 1005 Score = 103 bits (256), Expect = 5e-22 Identities = 54/140 (38%), Positives = 81/140 (57%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 L S S D T+ LW+ + +TGH V V FSPDG LAS++ D ++KLW+ Sbjct: 741 LASASGDKTIKLWDIQDGTCLQT-LTGHTDWVRCVAFSPDGNTLASSAADHTIKLWDVSQ 799 Query: 193 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVD 372 GK + + H V +++SAD + L SGS D T+K+W+ + + GH + VY++ Sbjct: 800 GKCLRTLKSHTGWVRSVAFSADGQTLASGSGDRTIKIWNYHTGECLKTYIGHTNSVYSIA 859 Query: 373 WSPDGEKVVSGGKDRALKLW 432 +SPD + +VSG DR +KLW Sbjct: 860 YSPDSKILVSGSGDRTIKLW 879 Score = 102 bits (253), Expect = 1e-21 Identities = 51/140 (36%), Positives = 81/140 (57%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 L SGS+D T+ LW+ K + + GH + + FSPD Q LASAS D SV+LWN T Sbjct: 951 LASGSNDKTVKLWDWQTGKYISS-LEGHTDFIYGIAFSPDSQTLASASTDSSVRLWNIST 1009 Query: 193 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVD 372 G+ H VY + + +++ +GS D T+K+W+I + + L H+D++ + Sbjct: 1010 GQCFQILLEHTDWVYAVVFHPQGKIIATGSADCTVKLWNISTGQCLKTLSEHSDKILGMA 1069 Query: 373 WSPDGEKVVSGGKDRALKLW 432 WSPDG+ + S D++++LW Sbjct: 1070 WSPDGQLLASASADQSVRLW 1089 Score = 97.4 bits (241), Expect = 3e-20 Identities = 50/140 (35%), Positives = 83/140 (59%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 + +GS D T+ LW + + K ++ H + + +SPDGQ LASAS D+SV+LW+ T Sbjct: 1035 IATGSADCTVKLWNISTGQCLKT-LSEHSDKILGMAWSPDGQLLASASADQSVRLWDCCT 1093 Query: 193 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVD 372 G+ V RGH VY +S + ++ + S D T+K+WD + K + L GH + V+ + Sbjct: 1094 GRCVGILRGHSNRVYSAIFSPNGEIIATCSTDQTVKIWDWQQGKCLKTLTGHTNWVFDIA 1153 Query: 373 WSPDGEKVVSGGKDRALKLW 432 +SPDG+ + S D+ +++W Sbjct: 1154 FSPDGKILASASHDQTVRIW 1173 Score = 96.7 bits (239), Expect = 5e-20 Identities = 49/140 (35%), Positives = 80/140 (57%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 L S S D ++ LW+ + + + GH V FSP+G+ +A+ S D++VK+W+ Sbjct: 1077 LASASADQSVRLWD-CCTGRCVGILRGHSNRVYSAIFSPNGEIIATCSTDQTVKIWDWQQ 1135 Query: 193 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVD 372 GK + GH V+ I++S D ++L S S D T+++WD+ K GH V +V Sbjct: 1136 GKCLKTLTGHTNWVFDIAFSPDGKILASASHDQTVRIWDVNTGKCHHICIGHTHLVSSVA 1195 Query: 373 WSPDGEKVVSGGKDRALKLW 432 +SPDGE V SG +D+ +++W Sbjct: 1196 FSPDGEVVASGSQDQTVRIW 1215 Score = 95.9 bits (237), Expect = 8e-20 Identities = 48/106 (45%), Positives = 69/106 (65%) Frame = +1 Query: 115 VYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDST 294 V FSPD Q LAS S DK+VKLW+ TGK++++ GH +Y I++S DS+ L S S DS+ Sbjct: 942 VAFSPDRQILASGSNDKTVKLWDWQTGKYISSLEGHTDFIYGIAFSPDSQTLASASTDSS 1001 Query: 295 LKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 +++W+I + Q L H D VYAV + P G+ + +G D +KLW Sbjct: 1002 VRLWNISTGQCFQILLEHTDWVYAVVFHPQGKIIATGSADCTVKLW 1047 Score = 95.5 bits (236), Expect = 1e-19 Identities = 47/114 (41%), Positives = 63/114 (55%) Frame = +1 Query: 91 GHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLL 270 GH V V FSPDG+ LAS D++VKLW+ G + GH +V+ +++ D L Sbjct: 682 GHSNWVRFVVFSPDGEILASCGADENVKLWSVRDGVCIKTLTGHEHEVFSVAFHPDGETL 741 Query: 271 LSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 S S D T+K+WDI+ Q L GH D V V +SPDG + S D +KLW Sbjct: 742 ASASGDKTIKLWDIQDGTCLQTLTGHTDWVRCVAFSPDGNTLASSAADHTIKLW 795 Score = 91.3 bits (225), Expect = 2e-18 Identities = 46/116 (39%), Positives = 67/116 (57%) Frame = +1 Query: 85 MTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSR 264 +TGH+ V V F PDG+ LASAS DK++KLW+ G + GH V +++S D Sbjct: 722 LTGHEHEVFSVAFHPDGETLASASGDKTIKLWDIQDGTCLQTLTGHTDWVRCVAFSPDGN 781 Query: 265 LLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 L S + D T+K+WD+ K + L H V +V +S DG+ + SG DR +K+W Sbjct: 782 TLASSAADHTIKLWDVSQGKCLRTLKSHTGWVRSVAFSADGQTLASGSGDRTIKIW 837 Score = 83.2 bits (204), Expect = 6e-16 Identities = 46/140 (32%), Positives = 75/140 (53%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 L S S D ++ LW + Q + H V V F P G+ +A+ S D +VKLWN T Sbjct: 993 LASASTDSSVRLWNISTG-QCFQILLEHTDWVYAVVFHPQGKIIATGSADCTVKLWNIST 1051 Query: 193 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVD 372 G+ + H + ++WS D +LL S S D ++++WD + L GH++ VY+ Sbjct: 1052 GQCLKTLSEHSDKILGMAWSPDGQLLASASADQSVRLWDCCTGRCVGILRGHSNRVYSAI 1111 Query: 373 WSPDGEKVVSGGKDRALKLW 432 +SP+GE + + D+ +K+W Sbjct: 1112 FSPNGEIIATCSTDQTVKIW 1131 Score = 78.6 bits (192), Expect = 1e-14 Identities = 39/104 (37%), Positives = 58/104 (55%) Frame = +1 Query: 121 FSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLK 300 FSP+GQ LA+ D V++W +GK + RGH V + +S D +L S D +K Sbjct: 650 FSPEGQLLATCDTDCHVRVWEVKSGKLLLICRGHSNWVRFVVFSPDGEILASCGADENVK 709 Query: 301 VWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 +W +R + L GH EV++V + PDGE + S D+ +KLW Sbjct: 710 LWSVRDGVCIKTLTGHEHEVFSVAFHPDGETLASASGDKTIKLW 753 Score = 71.2 bits (173), Expect = 2e-12 Identities = 39/105 (37%), Positives = 63/105 (60%) Frame = +1 Query: 25 SDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFV 204 S D T+ +W+ K K +TGH V + FSPDG+ LASAS D++V++W+ TGK Sbjct: 1123 STDQTVKIWDWQQGKCLKT-LTGHTNWVFDIAFSPDGKILASASHDQTVRIWDVNTGKCH 1181 Query: 205 TAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDL 339 GH V +++S D ++ SGS+D T+++W+++ + Q L Sbjct: 1182 HICIGHTHLVSSVAFSPDGEVVASGSQDQTVRIWNVKTGECLQIL 1226 Score = 48.5 bits (114), Expect = 2e-05 Identities = 24/74 (32%), Positives = 43/74 (58%) Frame = +1 Query: 211 FRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGE 390 F + ++ ++S + +LL + D ++VW++++ KL GH++ V V +SPDGE Sbjct: 638 FTETLGNILSAAFSPEGQLLATCDTDCHVRVWEVKSGKLLLICRGHSNWVRFVVFSPDGE 697 Query: 391 KVVSGGKDRALKLW 432 + S G D +KLW Sbjct: 698 ILASCGADENVKLW 711 Score = 47.4 bits (111), Expect = 3e-05 Identities = 26/68 (38%), Positives = 40/68 (58%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 L S S D T+ +W+ K + GH +V+ V FSPDG+ +AS S D++V++WN T Sbjct: 1161 LASASHDQTVRIWDVNTGKCHHICI-GHTHLVSSVAFSPDGEVVASGSQDQTVRIWNVKT 1219 Query: 193 GKFVTAFR 216 G+ + R Sbjct: 1220 GECLQILR 1227
>TUP12_SCHPO (Q9UUG8) Transcriptional repressor tup12| Length = 586 Score = 103 bits (258), Expect = 3e-22 Identities = 56/152 (36%), Positives = 84/152 (55%), Gaps = 12/152 (7%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 LVSGS D T+ LW+ +Q T V V FSPDGQ++A+ S DK +++W + Sbjct: 391 LVSGSGDRTVCLWDVEAGEQKLILHTDDG--VTTVMFSPDGQFIAAGSLDKVIRIWTS-S 447 Query: 193 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARK------------LKQD 336 G V GH VY +++S D + L+SGS D+T+K+W+++ KQ Sbjct: 448 GTLVEQLHGHEESVYSVAFSPDGKYLVSGSLDNTIKLWELQCVSNVAPSMYKEGGICKQT 507 Query: 337 LPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 GH D + +V SPDG+ ++SG KDR ++ W Sbjct: 508 FTGHKDFILSVTVSPDGKWIISGSKDRTIQFW 539 Score = 81.6 bits (200), Expect = 2e-15 Identities = 53/164 (32%), Positives = 90/164 (54%), Gaps = 7/164 (4%) Frame = +1 Query: 52 EPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVA- 228 EP IS Q + H V+ +V FS DG++LA+ +++ ++N TGK +T + + Sbjct: 273 EPPISVQLLHTLE-HTSVICYVRFSADGKFLATGC-NRAAMVFNVETGKLITLLQEESSK 330 Query: 229 ---DVY--QISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEK 393 D+Y +++S D + L +G +D +++WDI +++ + L GH E+Y++D+S DG+ Sbjct: 331 REGDLYVRSVAFSPDGKYLATGVEDQQIRIWDIAQKRVYRLLTGHEQEIYSLDFSKDGKT 390 Query: 394 VVSGGKDRALKLWMN*ACL*YHHECY*DDKCDDQ-FIEHVDDGV 522 +VSG DR + LW D + +Q I H DDGV Sbjct: 391 LVSGSGDRTVCLW--------------DVEAGEQKLILHTDDGV 420 Score = 75.1 bits (183), Expect = 2e-13 Identities = 47/155 (30%), Positives = 76/155 (49%), Gaps = 15/155 (9%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWN--- 183 + +GS D + +W T S ++ GH++ V V FSPDG++L S S D ++KLW Sbjct: 432 IAAGSLDKVIRIW--TSSGTLVEQLHGHEESVYSVAFSPDGKYLVSGSLDNTIKLWELQC 489 Query: 184 ------------GITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKL 327 GI + F GH + ++ S D + ++SGSKD T++ W + Sbjct: 490 VSNVAPSMYKEGGICKQ---TFTGHKDFILSVTVSPDGKWIISGSKDRTIQFWSPDSPHS 546 Query: 328 KQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 + L GH + V +V SP+G +G D ++W Sbjct: 547 QLTLQGHNNSVISVAVSPNGHCFATGSGDLRARIW 581 Score = 37.4 bits (85), Expect = 0.035 Identities = 19/57 (33%), Positives = 29/57 (50%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWN 183 ++SGS D T+ W P S + + GH V V SP+G A+ S D ++W+ Sbjct: 527 IISGSKDRTIQFWSPD-SPHSQLTLQGHNNSVISVAVSPNGHCFATGSGDLRARIWS 582
>PKWA_THECU (P49695) Probable serine/threonine-protein kinase pkwA (EC| 2.7.11.1) Length = 742 Score = 102 bits (254), Expect = 9e-22 Identities = 53/140 (37%), Positives = 81/140 (57%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 L SGSDD T+ LW+ +++ +A GH V + FSPDG +AS S D + +LWN T Sbjct: 516 LASGSDDATVRLWDVAAAEE-RAVFEGHTHYVLDIAFSPDGSMVASGSRDGTARLWNVAT 574 Query: 193 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVD 372 G +GH VY +++S D ++ SGS+D T+++WD+ K + L A+ V ++ Sbjct: 575 GTEHAVLKGHTDYVYAVAFSPDGSMVASGSRDGTIRLWDVATGKERDVLQAPAENVVSLA 634 Query: 373 WSPDGEKVVSGGKDRALKLW 432 +SPDG +V G D + LW Sbjct: 635 FSPDGSMLVH-GSDSTVHLW 653 Score = 100 bits (250), Expect = 3e-21 Identities = 54/140 (38%), Positives = 75/140 (53%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 L GS D + +W+ S + GH V V FSPDG LAS S D +V+LW+ Sbjct: 474 LAGGSGDKLIHVWD-VASGDELHTLEGHTDWVRAVAFSPDGALLASGSDDATVRLWDVAA 532 Query: 193 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVD 372 + F GH V I++S D ++ SGS+D T ++W++ L GH D VYAV Sbjct: 533 AEERAVFEGHTHYVLDIAFSPDGSMVASGSRDGTARLWNVATGTEHAVLKGHTDYVYAVA 592 Query: 373 WSPDGEKVVSGGKDRALKLW 432 +SPDG V SG +D ++LW Sbjct: 593 FSPDGSMVASGSRDGTIRLW 612 Score = 92.4 bits (228), Expect = 9e-19 Identities = 48/140 (34%), Positives = 79/140 (56%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 + SGS D T+ LW+ K+ + VV+ + FSPDG L S D +V LW+ + Sbjct: 600 VASGSRDGTIRLWDVATGKERDVLQAPAENVVS-LAFSPDGSMLVHGS-DSTVHLWDVAS 657 Query: 193 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVD 372 G+ + F GH V +++S D LL SGS D T+++WD+ A++ L GH + V++V Sbjct: 658 GEALHTFEGHTDWVRAVAFSPDGALLASGSDDRTIRLWDVAAQEEHTTLEGHTEPVHSVA 717 Query: 373 WSPDGEKVVSGGKDRALKLW 432 + P+G + S +D +++W Sbjct: 718 FHPEGTTLASASEDGTIRIW 737 Score = 83.6 bits (205), Expect = 4e-16 Identities = 44/127 (34%), Positives = 67/127 (52%) Frame = +1 Query: 52 EPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVAD 231 +P +P+ T + V V FSP G LA S DK + +W+ +G + GH Sbjct: 446 DPHELNEPRILTTDREAVA--VAFSPGGSLLAGGSGDKLIHVWDVASGDELHTLEGHTDW 503 Query: 232 VYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGK 411 V +++S D LL SGS D+T+++WD+ A + + GH V + +SPDG V SG + Sbjct: 504 VRAVAFSPDGALLASGSDDATVRLWDVAAAEERAVFEGHTHYVLDIAFSPDGSMVASGSR 563 Query: 412 DRALKLW 432 D +LW Sbjct: 564 DGTARLW 570 Score = 65.5 bits (158), Expect = 1e-10 Identities = 36/100 (36%), Positives = 54/100 (54%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 LV GSD T+ LW+ S + GH V V FSPDG LAS S D++++LW+ Sbjct: 642 LVHGSDS-TVHLWD-VASGEALHTFEGHTDWVRAVAFSPDGALLASGSDDRTIRLWDVAA 699 Query: 193 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDI 312 + T GH V+ +++ + L S S+D T+++W I Sbjct: 700 QEEHTTLEGHTEPVHSVAFHPEGTTLASASEDGTIRIWPI 739
>GBLP_DROME (O18640) Guanine nucleotide-binding protein beta subunit-like| protein (Receptor of activated protein kinase C homolog) Length = 318 Score = 101 bits (252), Expect = 2e-21 Identities = 54/151 (35%), Positives = 86/151 (56%), Gaps = 8/151 (5%) Frame = +1 Query: 4 PXRLVSGSDDFTMFLWEPTISKQ-----PKARMTGHQKVVNHVYFSPDGQWLASASFDKS 168 P ++S S D T+ +W+ T + P+ R+ GH ++ V S DG + S S+D++ Sbjct: 28 PDTIISASRDKTLIVWKLTRDEDTNYGYPQKRLYGHSHFISDVVLSSDGNYALSGSWDQT 87 Query: 169 VKLWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRAR-KLKQDLPG 345 ++LW+ GK F GH DV +++SAD+R ++SGS+D T+K+W+ A K G Sbjct: 88 LRLWDLAAGKTTRRFEGHTKDVLSVAFSADNRQIVSGSRDKTIKLWNTLAECKFTIQEDG 147 Query: 346 HADEVYAVDWSPDGEK--VVSGGKDRALKLW 432 H D V V +SP+ +VS G DR +K+W Sbjct: 148 HTDWVSCVRFSPNHSNPIIVSCGWDRTVKVW 178 Score = 60.1 bits (144), Expect = 5e-09 Identities = 41/127 (32%), Positives = 62/127 (48%), Gaps = 2/127 (1%) Frame = +1 Query: 10 RLVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPD--GQWLASASFDKSVKLWN 183 ++VSGS D T+ LW + + GH V+ V FSP+ + S +D++VK+WN Sbjct: 120 QIVSGSRDKTIKLWNTLAECKFTIQEDGHTDWVSCVRFSPNHSNPIIVSCGWDRTVKVWN 179 Query: 184 GITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVY 363 K GH + ++ S D L SG KDS +WD+ K L H D + Sbjct: 180 LANCKLKNNHHGHNGYLNTVTVSPDGSLCTSGGKDSKALLWDLNDGKNLYTLE-HNDIIN 238 Query: 364 AVDWSPD 384 A+ +SP+ Sbjct: 239 ALCFSPN 245 Score = 50.8 bits (120), Expect = 3e-06 Identities = 33/107 (30%), Positives = 50/107 (46%), Gaps = 9/107 (8%) Frame = +1 Query: 19 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 198 SG D LW+ K H ++N + FSP+ WL A + S+K+W+ K Sbjct: 210 SGGKDSKALLWDLNDGKN--LYTLEHNDIINALCFSPNRYWLCVA-YGPSIKIWDLACKK 266 Query: 199 FVTAFRGHV------ADVYQ---ISWSADSRLLLSGSKDSTLKVWDI 312 V R V AD Q ++WS D + L +G D+T++VW + Sbjct: 267 TVEELRPEVVSPTSKADQPQCLSLAWSTDGQTLFAGYSDNTIRVWQV 313 Score = 37.7 bits (86), Expect = 0.027 Identities = 27/79 (34%), Positives = 39/79 (49%), Gaps = 7/79 (8%) Frame = +1 Query: 217 GHVADVYQISWSA-DSRLLLSGSKDSTLKVW------DIRARKLKQDLPGHADEVYAVDW 375 GH V QI+ + D ++S S+D TL VW D ++ L GH+ + V Sbjct: 13 GHNGWVTQIATNPKDPDTIISASRDKTLIVWKLTRDEDTNYGYPQKRLYGHSHFISDVVL 72 Query: 376 SPDGEKVVSGGKDRALKLW 432 S DG +SG D+ L+LW Sbjct: 73 SSDGNYALSGSWDQTLRLW 91
>GBLP_NEUCR (Q01369) Guanine nucleotide-binding protein beta subunit-like| protein (Cross-pathway control WD-repeat protein cpc-2) Length = 316 Score = 101 bits (251), Expect = 2e-21 Identities = 57/155 (36%), Positives = 89/155 (57%), Gaps = 7/155 (4%) Frame = +1 Query: 4 PXRLVSGSDDFTMFLWEPTISKQ----PKARMTGHQKVVNHVYFSPDGQWLASASFDKSV 171 P L+SGS D ++ +W T + PK R+ GH +V+ S DG + SAS+DK++ Sbjct: 28 PNMLLSGSRDKSLIIWNLTRDETSYGYPKRRLHGHSHIVSDCVISSDGAYALSASWDKTL 87 Query: 172 KLWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWD-IRARKLKQDLPGH 348 +LW TG F GH DV +S+SAD+R ++SGS+D T+K+W+ + K GH Sbjct: 88 RLWELSTGTTTRRFVGHTNDVLSVSFSADNRQIVSGSRDRTIKLWNTLGDCKFTITEKGH 147 Query: 349 ADEVYAVDWSPDGEK--VVSGGKDRALKLWMN*AC 447 + V V +SP+ + +VS G D+ +K+W +C Sbjct: 148 TEWVSCVRFSPNPQNPVIVSSGWDKLVKVWELSSC 182 Score = 65.9 bits (159), Expect = 9e-11 Identities = 43/127 (33%), Positives = 66/127 (51%), Gaps = 2/127 (1%) Frame = +1 Query: 10 RLVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQ--WLASASFDKSVKLWN 183 ++VSGS D T+ LW + GH + V+ V FSP+ Q + S+ +DK VK+W Sbjct: 119 QIVSGSRDRTIKLWNTLGDCKFTITEKGHTEWVSCVRFSPNPQNPVIVSSGWDKLVKVWE 178 Query: 184 GITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVY 363 + K T GH + ++ S D L SG KD T +WD+ K L + DE++ Sbjct: 179 LSSCKLQTDHIGHTGYINAVTISPDGSLCASGGKDGTTMLWDLNESKHLYSLNAN-DEIH 237 Query: 364 AVDWSPD 384 A+ +SP+ Sbjct: 238 ALVFSPN 244 Score = 37.4 bits (85), Expect = 0.035 Identities = 26/110 (23%), Positives = 51/110 (46%), Gaps = 9/110 (8%) Frame = +1 Query: 19 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASAS--------FDKSVK 174 SG D T LW+ SK + + ++ + FSP+ WL +A+ +K K Sbjct: 209 SGGKDGTTMLWDLNESKHLYSLNANDE--IHALVFSPNRYWLCAATSSSIIIFDLEKKSK 266 Query: 175 LWNGITGKFVT-AFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRAR 321 + + + +F + + ++WSAD + L +G D+ ++ W + +R Sbjct: 267 V-DELKPEFQNIGKKSREPECVSLAWSADGQTLFAGYTDNIIRAWGVMSR 315
>WD51A_MOUSE (Q8JZX3) WD-repeat protein 51A| Length = 405 Score = 97.4 bits (241), Expect = 3e-20 Identities = 54/141 (38%), Positives = 76/141 (53%), Gaps = 1/141 (0%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKA-RMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGI 189 L SGS D T+ +W + Q +A R TGH+ V V FSP G LAS S DK+V++W Sbjct: 34 LASGSMDSTLMIWH--MKPQSRAYRFTGHKDAVTCVNFSPSGHLLASGSRDKTVRIWVPN 91 Query: 190 TGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAV 369 T FR H A V + + +D + L++ S D T+KVW ++ L H + V Sbjct: 92 VKGESTVFRAHTATVRSVHFCSDGQSLVTASDDKTVKVWSTHRQRFLFSLTQHINWVRCA 151 Query: 370 DWSPDGEKVVSGGKDRALKLW 432 +SPDG +VS D+ +KLW Sbjct: 152 KFSPDGRLIVSASDDKTVKLW 172 Score = 89.0 bits (219), Expect = 1e-17 Identities = 49/140 (35%), Positives = 73/140 (52%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 L SGS D T+ +W P + K H V V+F DGQ L +AS DK+VK+W+ Sbjct: 76 LASGSRDKTVRIWVPNV-KGESTVFRAHTATVRSVHFCSDGQSLVTASDDKTVKVWSTHR 134 Query: 193 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVD 372 +F+ + H+ V +S D RL++S S D T+K+WD +R+ H V VD Sbjct: 135 QRFLFSLTQHINWVRCAKFSPDGRLIVSASDDKTVKLWDKTSRECIHSYCEHGGFVTYVD 194 Query: 373 WSPDGEKVVSGGKDRALKLW 432 + P G + + G D +K+W Sbjct: 195 FHPSGTCIAAAGMDNTVKVW 214 Score = 84.0 bits (206), Expect = 3e-16 Identities = 48/140 (34%), Positives = 73/140 (52%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 +VS SDD T+ LW+ T S++ H V +V F P G +A+A D +VK+W+ T Sbjct: 160 IVSASDDKTVKLWDKT-SRECIHSYCEHGGFVTYVDFHPSGTCIAAAGMDNTVKVWDART 218 Query: 193 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVD 372 + + ++ H A V +S+ L++ S DSTLK+ D+ +L L GH V Sbjct: 219 HRLLQHYQLHSAAVNALSFHPSGNYLITASSDSTLKILDLMEGRLLYTLHGHQGPATTVA 278 Query: 373 WSPDGEKVVSGGKDRALKLW 432 +S GE SGG D + +W Sbjct: 279 FSRTGEYFASGGSDEQVMVW 298 Score = 77.8 bits (190), Expect = 2e-14 Identities = 44/139 (31%), Positives = 73/139 (52%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 LV+ SDD T+ +W T ++ +T H V FSPDG+ + SAS DK+VKLW+ + Sbjct: 118 LVTASDDKTVKVWS-THRQRFLFSLTQHINWVRCAKFSPDGRLIVSASDDKTVKLWDKTS 176 Query: 193 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVD 372 + + ++ H V + + + + D+T+KVWD R +L Q H+ V A+ Sbjct: 177 RECIHSYCEHGGFVTYVDFHPSGTCIAAAGMDNTVKVWDARTHRLLQHYQLHSAAVNALS 236 Query: 373 WSPDGEKVVSGGKDRALKL 429 + P G +++ D LK+ Sbjct: 237 FHPSGNYLITASSDSTLKI 255 Score = 63.9 bits (154), Expect = 3e-10 Identities = 34/114 (29%), Positives = 57/114 (50%) Frame = +1 Query: 91 GHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLL 270 GH+ V V FS + + LAS S D ++ +W+ F GH V +++S LL Sbjct: 17 GHRDAVTCVDFSLNTKHLASGSMDSTLMIWHMKPQSRAYRFTGHKDAVTCVNFSPSGHLL 76 Query: 271 LSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 SGS+D T+++W + H V +V + DG+ +V+ D+ +K+W Sbjct: 77 ASGSRDKTVRIWVPNVKGESTVFRAHTATVRSVHFCSDGQSLVTASDDKTVKVW 130 Score = 60.1 bits (144), Expect = 5e-09 Identities = 26/75 (34%), Positives = 45/75 (60%) Frame = +1 Query: 211 FRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGE 390 F+GH V + +S +++ L SGS DSTL +W ++ + GH D V V++SP G Sbjct: 15 FKGHRDAVTCVDFSLNTKHLASGSMDSTLMIWHMKPQSRAYRFTGHKDAVTCVNFSPSGH 74 Query: 391 KVVSGGKDRALKLWM 435 + SG +D+ +++W+ Sbjct: 75 LLASGSRDKTVRIWV 89 Score = 30.0 bits (66), Expect = 5.6 Identities = 13/36 (36%), Positives = 20/36 (55%) Frame = +1 Query: 325 LKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 L++ GH D V VD+S + + + SG D L +W Sbjct: 11 LERHFKGHRDAVTCVDFSLNTKHLASGSMDSTLMIW 46
>GBLP_DICDI (P46800) Guanine nucleotide-binding protein beta subunit-like| protein Length = 329 Score = 96.3 bits (238), Expect = 6e-20 Identities = 55/151 (36%), Positives = 87/151 (57%), Gaps = 8/151 (5%) Frame = +1 Query: 4 PXRLVSGSDDFTMFLWE--PTISKQP-KAR--MTGHQKVVNHVYFSPDGQWLASASFDKS 168 P ++S S D T+ +W+ PT + P KA + GH V V S DGQ+ S S+D + Sbjct: 34 PDTIISSSRDKTVMVWQLTPTDATSPGKAHRSLKGHSHFVQDVVISHDGQFALSGSWDNT 93 Query: 169 VKLWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPG- 345 ++LW+ G F+GH DV +++S+D+R ++SGS+D+T+KVW+ + K L G Sbjct: 94 LRLWDITKGVSTRLFKGHTQDVMSVAFSSDNRQIISGSRDATIKVWNTLG-ECKFTLEGP 152 Query: 346 --HADEVYAVDWSPDGEKVVSGGKDRALKLW 432 H D V + +SP+ +VSG D +K+W Sbjct: 153 EAHQDWVSCIRFSPNTPTIVSGSWDNKVKIW 183 Score = 51.6 bits (122), Expect = 2e-06 Identities = 39/144 (27%), Positives = 70/144 (48%), Gaps = 3/144 (2%) Frame = +1 Query: 10 RLVSGSDDFTMFLWEPTISKQPKARMTG---HQKVVNHVYFSPDGQWLASASFDKSVKLW 180 +++SGS D T+ +W + K + G HQ V+ + FSP+ + S S+D VK+W Sbjct: 126 QIISGSRDATIKVWNTL--GECKFTLEGPEAHQDWVSCIRFSPNTPTIVSGSWDNKVKIW 183 Query: 181 NGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEV 360 + + K H V ++ S D L SG KD+ +W++ + K L + + Sbjct: 184 DIKSFKCNHTLTDHTGYVNTVTISPDGSLCASGGKDTFACLWELSSGKPLYKLEAR-NTI 242 Query: 361 YAVDWSPDGEKVVSGGKDRALKLW 432 A+ +SP+ + +S D + +W Sbjct: 243 NALAFSPN-KYWLSAATDDKIIIW 265 Score = 44.3 bits (103), Expect = 3e-04 Identities = 37/157 (23%), Positives = 65/157 (41%), Gaps = 17/157 (10%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 +VSGS D + +W+ S + +T H VN V SPDG AS D LW + Sbjct: 171 IVSGSWDNKVKIWDIK-SFKCNHTLTDHTGYVNTVTISPDGSLCASGGKDTFACLWELSS 229 Query: 193 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRAR----------------- 321 GK ++ + + ++ LS + D + +WD+ + Sbjct: 230 GK--PLYKLEARNTINALAFSPNKYWLSAATDDKIIIWDLLTKQVLAEIVPEVKEQAFDS 287 Query: 322 KLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 K K++ A ++ WS DG + +G D ++++ Sbjct: 288 KKKKESKPKAPACLSLAWSADGSVLYAGYNDGLIRVY 324
>KTNB1_BRARE (Q7ZUV2) Katanin p80 WD40-containing subunit B1 homolog| Length = 694 Score = 94.7 bits (234), Expect = 2e-19 Identities = 53/134 (39%), Positives = 75/134 (55%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 L SGS D + LW+ K R GH + V + FSPDG+WLASAS D +VKLW+ I Sbjct: 120 LASGSVDSNIKLWDVR-RKGCVFRYKGHTQAVRCLAFSPDGKWLASASDDSTVKLWDLIA 178 Query: 193 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVD 372 GK +T F H + V + + + LL SGS D T+K+WD+ + G V +V Sbjct: 179 GKMITEFTSHTSAVNVVQFHPNEYLLASGSADRTVKLWDLEKFNMIGSSEGETGVVRSVL 238 Query: 373 WSPDGEKVVSGGKD 414 ++PDG + SG ++ Sbjct: 239 FNPDGSCLYSGSEN 252 Score = 90.9 bits (224), Expect = 3e-18 Identities = 49/141 (34%), Positives = 80/141 (56%) Frame = +1 Query: 10 RLVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGI 189 R+V+GS ++ LW+ +K + M GH+ ++ + F P G++LAS S D ++KLW+ Sbjct: 77 RVVAGSLSGSLRLWDLEAAKILRTLM-GHKASISSLDFHPMGEYLASGSVDSNIKLWDVR 135 Query: 190 TGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAV 369 V ++GH V +++S D + L S S DST+K+WD+ A K+ + H V V Sbjct: 136 RKGCVFRYKGHTQAVRCLAFSPDGKWLASASDDSTVKLWDLIAGKMITEFTSHTSAVNVV 195 Query: 370 DWSPDGEKVVSGGKDRALKLW 432 + P+ + SG DR +KLW Sbjct: 196 QFHPNEYLLASGSADRTVKLW 216 Score = 75.9 bits (185), Expect = 9e-14 Identities = 43/142 (30%), Positives = 69/142 (48%), Gaps = 2/142 (1%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARM--TGHQKVVNHVYFSPDGQWLASASFDKSVKLWNG 186 L +G +D + +W +SK P M TGH V + F+ + + + S S++LW+ Sbjct: 36 LATGGEDCRVNIW--AVSK-PNCIMSLTGHTSAVGCIQFNSSEERVVAGSLSGSLRLWDL 92 Query: 187 ITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYA 366 K + GH A + + + L SGS DS +K+WD+R + GH V Sbjct: 93 EAAKILRTLMGHKASISSLDFHPMGEYLASGSVDSNIKLWDVRRKGCVFRYKGHTQAVRC 152 Query: 367 VDWSPDGEKVVSGGKDRALKLW 432 + +SPDG+ + S D +KLW Sbjct: 153 LAFSPDGKWLASASDDSTVKLW 174 Score = 64.7 bits (156), Expect = 2e-10 Identities = 36/132 (27%), Positives = 64/132 (48%), Gaps = 1/132 (0%) Frame = +1 Query: 40 MFLWEPTISKQPKARMTGHQKVVNHVYFSPD-GQWLASASFDKSVKLWNGITGKFVTAFR 216 M L TI+ + H V+ + G+ LA+ D V +W + + Sbjct: 1 MALTNTTITSWKLQEIVAHSSNVSSLVLGKSSGRLLATGGEDCRVNIWAVSKPNCIMSLT 60 Query: 217 GHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKV 396 GH + V I +++ +++GS +L++WD+ A K+ + L GH + ++D+ P GE + Sbjct: 61 GHTSAVGCIQFNSSEERVVAGSLSGSLRLWDLEAAKILRTLMGHKASISSLDFHPMGEYL 120 Query: 397 VSGGKDRALKLW 432 SG D +KLW Sbjct: 121 ASGSVDSNIKLW 132 Score = 55.5 bits (132), Expect = 1e-07 Identities = 41/135 (30%), Positives = 62/135 (45%), Gaps = 2/135 (1%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 L S SDD T+ LW+ I+ + T H VN V F P+ LAS S D++VKLW+ Sbjct: 162 LASASDDSTVKLWD-LIAGKMITEFTSHTSAVNVVQFHPNEYLLASGSADRTVKLWDLEK 220 Query: 193 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKV--WDIRARKLKQDLPGHADEVYA 366 + + G V + ++ D L SGS ++TL+V W+ P +V Sbjct: 221 FNMIGSSEGETGVVRSVLFNPDGSCLYSGS-ENTLRVYGWE----------PDRCFDVVH 269 Query: 367 VDWSPDGEKVVSGGK 411 V W + +S + Sbjct: 270 VGWGKVSDLAISNNQ 284
>GBLP_HYDAT (Q25189) Guanine nucleotide-binding protein beta subunit-like| protein (Receptor of activated protein kinase C) (RACK) Length = 317 Score = 94.4 bits (233), Expect = 2e-19 Identities = 54/151 (35%), Positives = 87/151 (57%), Gaps = 8/151 (5%) Frame = +1 Query: 4 PXRLVSGSDDFTMFLWEPTISKQ-----PKARMTGHQKVVNHVYFSPDGQWLASASFDKS 168 P ++S S D T+ W+ T Q PK +TGH V+ V S DGQ+ S S+DK+ Sbjct: 27 PDLILSASRDKTLIQWQLTRDDQTNYGFPKKCLTGHNHFVSDVVLSSDGQFALSCSWDKT 86 Query: 169 VKLWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRAR-KLKQDLPG 345 ++LW+ G F GH DV +++SAD+R ++SGS+D+T+K+W+ + K Sbjct: 87 LRLWDLNQGITTKQFVGHTKDVLSVAFSADNRQIVSGSRDNTIKLWNTLGQCKYTIQDES 146 Query: 346 HADEVYAVDWSPDGEK--VVSGGKDRALKLW 432 H++ V V +SP+ + +VS G D+ +K+W Sbjct: 147 HSEWVSCVRFSPNTQNPIIVSCGWDKMVKVW 177 Score = 59.7 bits (143), Expect = 7e-09 Identities = 41/127 (32%), Positives = 62/127 (48%), Gaps = 2/127 (1%) Frame = +1 Query: 10 RLVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQ--WLASASFDKSVKLWN 183 ++VSGS D T+ LW + + H + V+ V FSP+ Q + S +DK VK+WN Sbjct: 119 QIVSGSRDNTIKLWNTLGQCKYTIQDESHSEWVSCVRFSPNTQNPIIVSCGWDKMVKVWN 178 Query: 184 GITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVY 363 K T GH + ++ S D L SG KD +WD+ K L G + + Sbjct: 179 LTNCKLKTNHFGHTGYLNAVTVSPDGSLCASGGKDGNAMLWDLNEGKHLYTLDG-GNVIN 237 Query: 364 AVDWSPD 384 A+ +SP+ Sbjct: 238 ALCFSPN 244 Score = 47.4 bits (111), Expect = 3e-05 Identities = 30/110 (27%), Positives = 51/110 (46%), Gaps = 12/110 (10%) Frame = +1 Query: 19 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWN----- 183 SG D LW+ K G+ V+N + FSP+ WL +A+ +K+W+ Sbjct: 209 SGGKDGNAMLWDLNEGKHLYTLDGGN--VINALCFSPNRYWLCAAT-GPMIKIWDLEMKS 265 Query: 184 -------GITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDI 312 G+ G + + AD ++WSAD + L +G D+ ++VW + Sbjct: 266 VVDELKPGVIG---ISTKSRAADCISLAWSADGQTLFAGYTDNLIRVWQV 312
>WD51A_HUMAN (Q8NBT0) WD-repeat protein 51A| Length = 407 Score = 94.0 bits (232), Expect = 3e-19 Identities = 53/142 (37%), Positives = 75/142 (52%), Gaps = 1/142 (0%) Frame = +1 Query: 10 RLVSGSDDFTMFLWEPTISKQPKA-RMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNG 186 +L SGS D + +W + Q +A R TGH+ V V FSP G LAS S DK+V++W Sbjct: 33 QLASGSMDSCLMVWH--MKPQSRAYRFTGHKDAVTCVNFSPSGHLLASGSRDKTVRIWVP 90 Query: 187 ITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYA 366 T FR H A V + + +D + ++ S D T+KVW +K L H + V Sbjct: 91 NVKGESTVFRAHTATVRSVHFCSDGQSFVTASDDKTVKVWATHRQKFLFSLSQHINWVRC 150 Query: 367 VDWSPDGEKVVSGGKDRALKLW 432 +SPDG +VS D+ +KLW Sbjct: 151 AKFSPDGRLIVSASDDKTVKLW 172 Score = 87.8 bits (216), Expect = 2e-17 Identities = 49/140 (35%), Positives = 71/140 (50%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 L SGS D T+ +W P + K H V V+F DGQ +AS DK+VK+W Sbjct: 76 LASGSRDKTVRIWVPNV-KGESTVFRAHTATVRSVHFCSDGQSFVTASDDKTVKVWATHR 134 Query: 193 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVD 372 KF+ + H+ V +S D RL++S S D T+K+WD +R+ H V VD Sbjct: 135 QKFLFSLSQHINWVRCAKFSPDGRLIVSASDDKTVKLWDKSSRECVHSYCEHGGFVTYVD 194 Query: 373 WSPDGEKVVSGGKDRALKLW 432 + P G + + G D +K+W Sbjct: 195 FHPSGTCIAAAGMDNTVKVW 214 Score = 81.3 bits (199), Expect = 2e-15 Identities = 47/140 (33%), Positives = 73/140 (52%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 +VS SDD T+ LW+ + S++ H V +V F P G +A+A D +VK+W+ T Sbjct: 160 IVSASDDKTVKLWDKS-SRECVHSYCEHGGFVTYVDFHPSGTCIAAAGMDNTVKVWDVRT 218 Query: 193 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVD 372 + + ++ H A V +S+ L++ S DSTLK+ D+ +L L GH V Sbjct: 219 HRLLQHYQLHSAAVNGLSFHPSGNYLITASSDSTLKILDLMEGRLLYTLHGHQGPATTVA 278 Query: 373 WSPDGEKVVSGGKDRALKLW 432 +S GE SGG D + +W Sbjct: 279 FSRTGEYFASGGSDEQVMVW 298 Score = 74.3 bits (181), Expect = 3e-13 Identities = 42/138 (30%), Positives = 72/138 (52%) Frame = +1 Query: 16 VSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITG 195 V+ SDD T+ +W T ++ ++ H V FSPDG+ + SAS DK+VKLW+ + Sbjct: 119 VTASDDKTVKVWA-THRQKFLFSLSQHINWVRCAKFSPDGRLIVSASDDKTVKLWDKSSR 177 Query: 196 KFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDW 375 + V ++ H V + + + + D+T+KVWD+R +L Q H+ V + + Sbjct: 178 ECVHSYCEHGGFVTYVDFHPSGTCIAAAGMDNTVKVWDVRTHRLLQHYQLHSAAVNGLSF 237 Query: 376 SPDGEKVVSGGKDRALKL 429 P G +++ D LK+ Sbjct: 238 HPSGNYLITASSDSTLKI 255 Score = 62.0 bits (149), Expect = 1e-09 Identities = 34/114 (29%), Positives = 55/114 (48%) Frame = +1 Query: 91 GHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLL 270 GH+ V V FS + + LAS S D + +W+ F GH V +++S LL Sbjct: 17 GHRDAVTCVDFSINTKQLASGSMDSCLMVWHMKPQSRAYRFTGHKDAVTCVNFSPSGHLL 76 Query: 271 LSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 SGS+D T+++W + H V +V + DG+ V+ D+ +K+W Sbjct: 77 ASGSRDKTVRIWVPNVKGESTVFRAHTATVRSVHFCSDGQSFVTASDDKTVKVW 130 Score = 58.5 bits (140), Expect = 1e-08 Identities = 26/75 (34%), Positives = 44/75 (58%) Frame = +1 Query: 211 FRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGE 390 F+GH V + +S +++ L SGS DS L VW ++ + GH D V V++SP G Sbjct: 15 FKGHRDAVTCVDFSINTKQLASGSMDSCLMVWHMKPQSRAYRFTGHKDAVTCVNFSPSGH 74 Query: 391 KVVSGGKDRALKLWM 435 + SG +D+ +++W+ Sbjct: 75 LLASGSRDKTVRIWV 89
>WD51A_BOVIN (Q2TBP4) WD-repeat protein 51A| Length = 407 Score = 92.8 bits (229), Expect = 7e-19 Identities = 52/142 (36%), Positives = 74/142 (52%), Gaps = 1/142 (0%) Frame = +1 Query: 10 RLVSGSDDFTMFLWEPTISKQPKA-RMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNG 186 +L SGS D + +W + Q +A R GH+ V V FSP G LAS S DK+V++W Sbjct: 33 QLASGSMDSCLMVWH--MKPQTRAYRFAGHKDAVTCVNFSPSGHLLASGSRDKTVRIWVP 90 Query: 187 ITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYA 366 T FR H A V + + +D + ++ S D T+KVW +K L H + V Sbjct: 91 NVKGESTVFRAHTATVRSVHFCSDGQSFVTASDDKTVKVWSTHRQKFLFSLSQHINWVRC 150 Query: 367 VDWSPDGEKVVSGGKDRALKLW 432 +SPDG +VS D+ +KLW Sbjct: 151 AKFSPDGRLIVSASDDKTVKLW 172 Score = 89.0 bits (219), Expect = 1e-17 Identities = 49/140 (35%), Positives = 72/140 (51%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 L SGS D T+ +W P + K H V V+F DGQ +AS DK+VK+W+ Sbjct: 76 LASGSRDKTVRIWVPNV-KGESTVFRAHTATVRSVHFCSDGQSFVTASDDKTVKVWSTHR 134 Query: 193 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVD 372 KF+ + H+ V +S D RL++S S D T+K+WD +R+ H V VD Sbjct: 135 QKFLFSLSQHINWVRCAKFSPDGRLIVSASDDKTVKLWDKTSRECVHSYCEHGGFVTYVD 194 Query: 373 WSPDGEKVVSGGKDRALKLW 432 + P G + + G D +K+W Sbjct: 195 FHPSGTCIAAAGMDNTVKVW 214 Score = 82.8 bits (203), Expect = 7e-16 Identities = 48/140 (34%), Positives = 73/140 (52%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 +VS SDD T+ LW+ T S++ H V +V F P G +A+A D +VK+W+ T Sbjct: 160 IVSASDDKTVKLWDKT-SRECVHSYCEHGGFVTYVDFHPSGTCIAAAGMDNTVKVWDVRT 218 Query: 193 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVD 372 + + ++ H A V +S+ L++ S DSTLK+ D+ +L L GH V Sbjct: 219 HRLLQHYQLHSAAVNALSFHPSGNYLVTASSDSTLKILDLMEGRLLYTLHGHQGPATTVA 278 Query: 373 WSPDGEKVVSGGKDRALKLW 432 +S GE SGG D + +W Sbjct: 279 FSRTGEYFASGGSDEQVMVW 298 Score = 77.0 bits (188), Expect = 4e-14 Identities = 44/138 (31%), Positives = 73/138 (52%) Frame = +1 Query: 16 VSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITG 195 V+ SDD T+ +W T ++ ++ H V FSPDG+ + SAS DK+VKLW+ + Sbjct: 119 VTASDDKTVKVWS-THRQKFLFSLSQHINWVRCAKFSPDGRLIVSASDDKTVKLWDKTSR 177 Query: 196 KFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDW 375 + V ++ H V + + + + D+T+KVWD+R +L Q H+ V A+ + Sbjct: 178 ECVHSYCEHGGFVTYVDFHPSGTCIAAAGMDNTVKVWDVRTHRLLQHYQLHSAAVNALSF 237 Query: 376 SPDGEKVVSGGKDRALKL 429 P G +V+ D LK+ Sbjct: 238 HPSGNYLVTASSDSTLKI 255 Score = 62.4 bits (150), Expect = 1e-09 Identities = 34/114 (29%), Positives = 55/114 (48%) Frame = +1 Query: 91 GHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLL 270 GH+ V V FS + + LAS S D + +W+ F GH V +++S LL Sbjct: 17 GHRDAVTSVDFSLNTKQLASGSMDSCLMVWHMKPQTRAYRFAGHKDAVTCVNFSPSGHLL 76 Query: 271 LSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 SGS+D T+++W + H V +V + DG+ V+ D+ +K+W Sbjct: 77 ASGSRDKTVRIWVPNVKGESTVFRAHTATVRSVHFCSDGQSFVTASDDKTVKVW 130 Score = 59.3 bits (142), Expect = 9e-09 Identities = 26/75 (34%), Positives = 44/75 (58%) Frame = +1 Query: 211 FRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGE 390 F+GH V + +S +++ L SGS DS L VW ++ + GH D V V++SP G Sbjct: 15 FKGHRDAVTSVDFSLNTKQLASGSMDSCLMVWHMKPQTRAYRFAGHKDAVTCVNFSPSGH 74 Query: 391 KVVSGGKDRALKLWM 435 + SG +D+ +++W+ Sbjct: 75 LLASGSRDKTVRIWV 89
>GBLP_SCHPO (Q10281) Guanine nucleotide-binding protein beta subunit-like| protein (Receptor of activated protein kinase C) Length = 314 Score = 92.4 bits (228), Expect = 9e-19 Identities = 55/150 (36%), Positives = 86/150 (57%), Gaps = 7/150 (4%) Frame = +1 Query: 4 PXRLVSGSDDFTMFLW----EPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSV 171 P L+SGS D ++ LW + + R+TGH V+ S D + SAS+DK++ Sbjct: 28 PDILLSGSRDKSIILWNLVRDDVNYGVAQRRLTGHSHFVSDCALSFDSHYALSASWDKTI 87 Query: 172 KLWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRAR-KLKQDLPGH 348 +LW+ G+ F GH +DV +S S D+R ++SGS+D T+K+W+I K GH Sbjct: 88 RLWDLEKGECTHQFVGHTSDVLSVSISPDNRQVVSGSRDKTIKIWNIIGNCKYTITDGGH 147 Query: 349 ADEVYAVDWSPDGEKV--VSGGKDRALKLW 432 +D V V +SP+ + + VS G D+A+K+W Sbjct: 148 SDWVSCVRFSPNPDNLTFVSAGWDKAVKVW 177 Score = 62.0 bits (149), Expect = 1e-09 Identities = 50/192 (26%), Positives = 76/192 (39%), Gaps = 51/192 (26%) Frame = +1 Query: 10 RLVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSP--DGQWLASASFDKSVKLWN 183 ++VSGS D T+ +W + + GH V+ V FSP D SA +DK+VK+W+ Sbjct: 119 QVVSGSRDKTIKIWNIIGNCKYTITDGGHSDWVSCVRFSPNPDNLTFVSAGWDKAVKVWD 178 Query: 184 GITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDI----------------- 312 T T+ GH V ++ S D L SG +D TL +WD+ Sbjct: 179 LETFSLRTSHYGHTGYVSAVTISPDGSLCASGGRDGTLMLWDLNESTHLYSLEAKANINA 238 Query: 313 ---------------------------RARKLKQDLPG-----HADEVYAVDWSPDGEKV 396 + +L D G E ++ WSPDG+ + Sbjct: 239 LVFSPNRYWLCAATGSSIRIFDLETQEKVDELTVDFVGVGKKSSEPECISLTWSPDGQTL 298 Query: 397 VSGGKDRALKLW 432 SG D +++W Sbjct: 299 FSGWTDNLIRVW 310 Score = 39.7 bits (91), Expect = 0.007 Identities = 26/107 (24%), Positives = 52/107 (48%), Gaps = 9/107 (8%) Frame = +1 Query: 19 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWN----- 183 SG D T+ LW+ +++ + +N + FSP+ WL +A+ S+++++ Sbjct: 209 SGGRDGTLMLWD--LNESTHLYSLEAKANINALVFSPNRYWLCAAT-GSSIRIFDLETQE 265 Query: 184 ---GITGKFV-TAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDI 312 +T FV + + ++WS D + L SG D+ ++VW + Sbjct: 266 KVDELTVDFVGVGKKSSEPECISLTWSPDGQTLFSGWTDNLIRVWQV 312
>Y163_SYNY3 (Q55563) Hypothetical WD-repeat protein sll0163| Length = 1693 Score = 92.4 bits (228), Expect = 9e-19 Identities = 48/140 (34%), Positives = 78/140 (55%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 +++ S D T +W+ +P + GHQ +V FSP+G +A+ S D + +LW+ + Sbjct: 1521 ILTASVDNTARIWD--FLGRPLLTLAGHQSIVYQARFSPEGNLIATVSADHTARLWDR-S 1577 Query: 193 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVD 372 GK V GH V + WS D ++L++ S D T ++WD+ R+L L GH + V + + Sbjct: 1578 GKTVAVLYGHQGLVGTVDWSPDGQMLVTASNDGTARLWDLSGREL-LTLEGHGNWVRSAE 1636 Query: 373 WSPDGEKVVSGGKDRALKLW 432 +SPDG V++ D KLW Sbjct: 1637 FSPDGRWVLTSSADGTAKLW 1656 Score = 92.0 bits (227), Expect = 1e-18 Identities = 51/141 (36%), Positives = 79/141 (56%) Frame = +1 Query: 10 RLVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGI 189 RL++ S D T LW T + A + HQ V FSPDGQW+ + S DK+ +LWN + Sbjct: 1356 RLLTVSRDKTARLW--TTEGECVAVLADHQGWVREGQFSPDGQWIVTGSADKTAQLWN-V 1412 Query: 190 TGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAV 369 GK +T RGH V + +S DS+ +++ SKD T +VW+ R+L L + ++A Sbjct: 1413 LGKKLTVLRGHQDAVLNVRFSPDSQYIVTASKDGTARVWNNTGRELAV-LRHYEKNIFAA 1471 Query: 370 DWSPDGEKVVSGGKDRALKLW 432 ++S DG+ +V+ D +W Sbjct: 1472 EFSADGQFIVTASDDNTAGIW 1492 Score = 82.8 bits (203), Expect = 7e-16 Identities = 49/140 (35%), Positives = 74/140 (52%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 +V+ S D T +W T + A + ++K + FS DGQ++ +AS D + +W I Sbjct: 1439 IVTASKDGTARVWNNT--GRELAVLRHYEKNIFAAEFSADGQFIVTASDDNTAGIWE-IV 1495 Query: 193 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVD 372 G+ V RGH VY +SADSR +L+ S D+T ++WD R L L GH VY Sbjct: 1496 GREVGICRGHEGPVYFAQFSADSRYILTASVDNTARIWDFLGRPL-LTLAGHQSIVYQAR 1554 Query: 373 WSPDGEKVVSGGKDRALKLW 432 +SP+G + + D +LW Sbjct: 1555 FSPEGNLIATVSADHTARLW 1574 Score = 80.5 bits (197), Expect = 4e-15 Identities = 46/138 (33%), Positives = 74/138 (53%) Frame = +1 Query: 25 SDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFV 204 S D T W+ IS++ +TGH V + +F+P G L + S DK+ +LW G+ V Sbjct: 1320 SADQTARQWD--ISQKDTITLTGHSHWVRNAHFNPKGDRLLTVSRDKTARLWT-TEGECV 1376 Query: 205 TAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPD 384 H V + +S D + +++GS D T ++W++ +KL L GH D V V +SPD Sbjct: 1377 AVLADHQGWVREGQFSPDGQWIVTGSADKTAQLWNVLGKKLTV-LRGHQDAVLNVRFSPD 1435 Query: 385 GEKVVSGGKDRALKLWMN 438 + +V+ KD ++W N Sbjct: 1436 SQYIVTASKDGTARVWNN 1453 Score = 80.5 bits (197), Expect = 4e-15 Identities = 44/140 (31%), Positives = 71/140 (50%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 L++ S D T LW+ + + GH V + FSPDGQW+ + S D + +LW+ ++ Sbjct: 1152 LLTASRDGTARLWD--LEGREIGLCQGHTSWVRNAQFSPDGQWIVTCSADGTARLWD-LS 1208 Query: 193 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVD 372 + +GH V WS D + +++ S D T +VW R K L GH ++ Sbjct: 1209 SQCFAVLKGHQNWVNNALWSPDGQHIITSSSDGTARVWS-RHGKCLGTLRGHDHNIHGAR 1267 Query: 373 WSPDGEKVVSGGKDRALKLW 432 +S DG+K+V+ D +LW Sbjct: 1268 FSLDGQKIVTYSTDNTARLW 1287 Score = 77.4 bits (189), Expect = 3e-14 Identities = 42/138 (30%), Positives = 74/138 (53%) Frame = +1 Query: 19 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 198 + S D T+ LW+ + A + GH+ V V+FSP Q+L ++ D + ++WN G+ Sbjct: 1072 TASADHTVKLWQR--HGEEVATLRGHEDWVRSVHFSPHHQFLVTSGQDNTARIWN-FAGE 1128 Query: 199 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWS 378 +T +GH V ++ ++LL+ S+D T ++WD+ R++ GH V +S Sbjct: 1129 QLTLCQGHADWVRNAEFNCHGQILLTASRDGTARLWDLEGREIGL-CQGHTSWVRNAQFS 1187 Query: 379 PDGEKVVSGGKDRALKLW 432 PDG+ +V+ D +LW Sbjct: 1188 PDGQWIVTCSADGTARLW 1205 Score = 75.5 bits (184), Expect = 1e-13 Identities = 45/142 (31%), Positives = 75/142 (52%), Gaps = 2/142 (1%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMT--GHQKVVNHVYFSPDGQWLASASFDKSVKLWNG 186 +++ S D T +W S+ K T GH ++ FS DGQ + + S D + +LW Sbjct: 1234 IITSSSDGTARVW----SRHGKCLGTLRGHDHNIHGARFSLDGQKIVTYSTDNTARLWTK 1289 Query: 187 ITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYA 366 G +T RGH +VY +SAD R + + S D T + WDI ++K L GH+ V Sbjct: 1290 -EGTLLTILRGHQKEVYDADFSADGRFVFTVSADQTARQWDI-SQKDTITLTGHSHWVRN 1347 Query: 367 VDWSPDGEKVVSGGKDRALKLW 432 ++P G+++++ +D+ +LW Sbjct: 1348 AHFNPKGDRLLTVSRDKTARLW 1369 Score = 68.9 bits (167), Expect = 1e-11 Identities = 36/116 (31%), Positives = 65/116 (56%) Frame = +1 Query: 85 MTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSR 264 + GHQ+ + + +S DGQ+ A+AS D +VKLW G+ V RGH V + +S + Sbjct: 1051 LRGHQEAITALDWSADGQYFATASADHTVKLWQR-HGEEVATLRGHEDWVRSVHFSPHHQ 1109 Query: 265 LLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 L++ +D+T ++W+ +L GHAD V +++ G+ +++ +D +LW Sbjct: 1110 FLVTSGQDNTARIWNFAGEQLTL-CQGHADWVRNAEFNCHGQILLTASRDGTARLW 1164 Score = 61.6 bits (148), Expect = 2e-09 Identities = 36/97 (37%), Positives = 55/97 (56%) Frame = +1 Query: 25 SDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFV 204 S D T LW+ S + A + GHQ +V V +SPDGQ L +AS D + +LW+ ++G+ + Sbjct: 1566 SADHTARLWDR--SGKTVAVLYGHQGLVGTVDWSPDGQMLVTASNDGTARLWD-LSGREL 1622 Query: 205 TAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIR 315 GH V +S D R +L+ S D T K+W ++ Sbjct: 1623 LTLEGHGNWVRSAEFSPDGRWVLTSSADGTAKLWPVK 1659 Score = 56.2 bits (134), Expect = 7e-08 Identities = 27/86 (31%), Positives = 46/86 (53%) Frame = +1 Query: 175 LWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHAD 354 LW+ G+ + RGH + + WSAD + + S D T+K+W ++ L GH D Sbjct: 1040 LWS-FHGELINVLRGHQEAITALDWSADGQYFATASADHTVKLWQRHGEEV-ATLRGHED 1097 Query: 355 EVYAVDWSPDGEKVVSGGKDRALKLW 432 V +V +SP + +V+ G+D ++W Sbjct: 1098 WVRSVHFSPHHQFLVTSGQDNTARIW 1123
>GBLP_TRYBR (P69104) Guanine nucleotide-binding protein beta subunit-like| protein (Activated protein kinase C receptor homolog) (Track) Length = 318 Score = 92.4 bits (228), Expect = 9e-19 Identities = 53/152 (34%), Positives = 82/152 (53%), Gaps = 11/152 (7%) Frame = +1 Query: 10 RLVSGSDDFTMFLWEPTISKQ--------PKARMTGHQKVVNHVYFSPDGQWLASASFDK 165 ++VS S D T+ W P + P R+ GH V+ V S +G + SAS+D Sbjct: 30 KVVSTSRDKTLLSWGPNPDRHSSECSYGLPDRRLEGHSAFVSDVALSNNGNFAVSASWDH 89 Query: 166 SVKLWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPG 345 S++LWN G+ F GH DV +++S D+R ++SG +D+ L+VW+++ + G Sbjct: 90 SLRLWNLQNGQCQYKFLGHTKDVLSVAFSPDNRQIVSGGRDNALRVWNVKGECMHTLSRG 149 Query: 346 -HADEVYAVDWSP--DGEKVVSGGKDRALKLW 432 H D V V +SP D +VSGG D +K+W Sbjct: 150 AHTDWVSCVRFSPSLDAPVIVSGGWDNLVKVW 181 Score = 55.5 bits (132), Expect = 1e-07 Identities = 32/103 (31%), Positives = 48/103 (46%), Gaps = 2/103 (1%) Frame = +1 Query: 10 RLVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSP--DGQWLASASFDKSVKLWN 183 ++VSG D + +W H V+ V FSP D + S +D VK+W+ Sbjct: 123 QIVSGGRDNALRVWNVKGECMHTLSRGAHTDWVSCVRFSPSLDAPVIVSGGWDNLVKVWD 182 Query: 184 GITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDI 312 TG+ VT +GH V ++ S D L S KD ++WD+ Sbjct: 183 LATGRLVTDLKGHTNYVTSVTVSPDGSLCASSDKDGVARLWDL 225 Score = 51.2 bits (121), Expect = 2e-06 Identities = 37/147 (25%), Positives = 69/147 (46%), Gaps = 7/147 (4%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 +VSG D + +W+ + + GH V V SPDG AS+ D +LW+ Sbjct: 169 IVSGGWDNLVKVWDLATGRLV-TDLKGHTNYVTSVTVSPDGSLCASSDKDGVARLWDLTK 227 Query: 193 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDL-PGH------A 351 G+ ++ A + QI +S +R + + + ++++D+ + + +L P H Sbjct: 228 GEALSEMAAG-APINQICFS-PNRYWMCAATEKGIRIFDLENKDIIVELAPEHQGSKKIV 285 Query: 352 DEVYAVDWSPDGEKVVSGGKDRALKLW 432 E ++ WS DG + SG D +++W Sbjct: 286 PECVSIAWSADGSTLYSGYTDNVIRVW 312 Score = 40.4 bits (93), Expect = 0.004 Identities = 27/105 (25%), Positives = 49/105 (46%), Gaps = 7/105 (6%) Frame = +1 Query: 19 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWN----G 186 S D LW+ T + G +N + FSP+ W+ +A+ +K +++++ Sbjct: 213 SSDKDGVARLWDLTKGEALSEMAAGAP--INQICFSPNRYWMCAAT-EKGIRIFDLENKD 269 Query: 187 ITGKFVTAFRGH---VADVYQISWSADSRLLLSGSKDSTLKVWDI 312 I + +G V + I+WSAD L SG D+ ++VW + Sbjct: 270 IIVELAPEHQGSKKIVPECVSIAWSADGSTLYSGYTDNVIRVWGV 314
>GBLP_TRYBB (P69103) Guanine nucleotide-binding protein beta subunit-like| protein (Activated protein kinase C receptor homolog) Length = 318 Score = 92.4 bits (228), Expect = 9e-19 Identities = 53/152 (34%), Positives = 82/152 (53%), Gaps = 11/152 (7%) Frame = +1 Query: 10 RLVSGSDDFTMFLWEPTISKQ--------PKARMTGHQKVVNHVYFSPDGQWLASASFDK 165 ++VS S D T+ W P + P R+ GH V+ V S +G + SAS+D Sbjct: 30 KVVSTSRDKTLLSWGPNPDRHSSECSYGLPDRRLEGHSAFVSDVALSNNGNFAVSASWDH 89 Query: 166 SVKLWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPG 345 S++LWN G+ F GH DV +++S D+R ++SG +D+ L+VW+++ + G Sbjct: 90 SLRLWNLQNGQCQYKFLGHTKDVLSVAFSPDNRQIVSGGRDNALRVWNVKGECMHTLSRG 149 Query: 346 -HADEVYAVDWSP--DGEKVVSGGKDRALKLW 432 H D V V +SP D +VSGG D +K+W Sbjct: 150 AHTDWVSCVRFSPSLDAPVIVSGGWDNLVKVW 181 Score = 55.5 bits (132), Expect = 1e-07 Identities = 32/103 (31%), Positives = 48/103 (46%), Gaps = 2/103 (1%) Frame = +1 Query: 10 RLVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSP--DGQWLASASFDKSVKLWN 183 ++VSG D + +W H V+ V FSP D + S +D VK+W+ Sbjct: 123 QIVSGGRDNALRVWNVKGECMHTLSRGAHTDWVSCVRFSPSLDAPVIVSGGWDNLVKVWD 182 Query: 184 GITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDI 312 TG+ VT +GH V ++ S D L S KD ++WD+ Sbjct: 183 LATGRLVTDLKGHTNYVTSVTVSPDGSLCASSDKDGVARLWDL 225 Score = 51.2 bits (121), Expect = 2e-06 Identities = 37/147 (25%), Positives = 69/147 (46%), Gaps = 7/147 (4%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 +VSG D + +W+ + + GH V V SPDG AS+ D +LW+ Sbjct: 169 IVSGGWDNLVKVWDLATGRLV-TDLKGHTNYVTSVTVSPDGSLCASSDKDGVARLWDLTK 227 Query: 193 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDL-PGH------A 351 G+ ++ A + QI +S +R + + + ++++D+ + + +L P H Sbjct: 228 GEALSEMAAG-APINQICFS-PNRYWMCAATEKGIRIFDLENKDIIVELAPEHQGSKKIV 285 Query: 352 DEVYAVDWSPDGEKVVSGGKDRALKLW 432 E ++ WS DG + SG D +++W Sbjct: 286 PECVSIAWSADGSTLYSGYTDNVIRVW 312 Score = 40.4 bits (93), Expect = 0.004 Identities = 27/105 (25%), Positives = 49/105 (46%), Gaps = 7/105 (6%) Frame = +1 Query: 19 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWN----G 186 S D LW+ T + G +N + FSP+ W+ +A+ +K +++++ Sbjct: 213 SSDKDGVARLWDLTKGEALSEMAAGAP--INQICFSPNRYWMCAAT-EKGIRIFDLENKD 269 Query: 187 ITGKFVTAFRGH---VADVYQISWSADSRLLLSGSKDSTLKVWDI 312 I + +G V + I+WSAD L SG D+ ++VW + Sbjct: 270 IIVELAPEHQGSKKIVPECVSIAWSADGSTLYSGYTDNVIRVWGV 314
>Y143_SYNY3 (P74442) Hypothetical WD-repeat protein slr0143| Length = 1191 Score = 92.4 bits (228), Expect = 9e-19 Identities = 45/116 (38%), Positives = 69/116 (59%) Frame = +1 Query: 85 MTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSR 264 +TGH+ V V S +ASAS D +V LW G+F+ F GH +Y++ +S + + Sbjct: 556 LTGHRDGVTSVAISSHKNLIASASRDGTVHLWTP-QGEFLREFTGHTGSIYRVDFSPNGK 614 Query: 265 LLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 + + +D T+K+WD+ L Q L GH D VY+V +SPDGE + S +DR ++LW Sbjct: 615 IFATAGQDQTVKIWDLDG-NLLQTLKGHQDSVYSVSFSPDGEILASTSRDRTVRLW 669 Score = 79.7 bits (195), Expect = 6e-15 Identities = 44/139 (31%), Positives = 73/139 (52%), Gaps = 1/139 (0%) Frame = +1 Query: 19 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 198 + D T+ +W+ + + GHQ V V FSPDG+ LAS S D++V+LW+ +GK Sbjct: 618 TAGQDQTVKIWD--LDGNLLQTLKGHQDSVYSVSFSPDGEILASTSRDRTVRLWHWRSGK 675 Query: 199 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQ-DLPGHADEVYAVDW 375 + GH V +S D + L+S +D +++WD+ ++Q LP A + V+W Sbjct: 676 TLAVLGGHTKSVDDAQFSPDGQTLVSVCRDGQIRLWDLDGNLIRQFGLPEVA--FFGVNW 733 Query: 376 SPDGEKVVSGGKDRALKLW 432 P+G + D ++LW Sbjct: 734 HPNGNLLAVAADDGTVRLW 752 Score = 69.3 bits (168), Expect = 8e-12 Identities = 43/140 (30%), Positives = 71/140 (50%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 L S S D T+ LW K A + GH K V+ FSPDGQ L S D ++LW+ + Sbjct: 657 LASTSRDRTVRLWHWRSGKT-LAVLGGHTKSVDDAQFSPDGQTLVSVCRDGQIRLWD-LD 714 Query: 193 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVD 372 G + F + ++W + LL + D T+++W + ++K L GH + V V Sbjct: 715 GNLIRQFGLPEVAFFGVNWHPNGNLLAVAADDGTVRLWTPQG-EIKATLSGHDEFVTRVV 773 Query: 373 WSPDGEKVVSGGKDRALKLW 432 ++PDG+++ S + ++ W Sbjct: 774 FTPDGKQLFSSSSNGSVIHW 793 Score = 63.5 bits (153), Expect = 5e-10 Identities = 33/100 (33%), Positives = 62/100 (62%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 L +DD T+ LW P + KA ++GH + V V F+PDG+ L S+S + SV W+ + Sbjct: 740 LAVAADDGTVRLWTP--QGEIKATLSGHDEFVTRVVFTPDGKQLFSSSSNGSVIHWS-TS 796 Query: 193 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDI 312 GK + ++G+ ++ ++ +++ LL G++++ +KVWD+ Sbjct: 797 GKMLKKYQGYPEAIFGLALASNGALLAIGAENNLVKVWDM 836 Score = 51.2 bits (121), Expect = 2e-06 Identities = 29/143 (20%), Positives = 75/143 (52%), Gaps = 2/143 (1%) Frame = +1 Query: 10 RLVSGSDDFTMFLW--EPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWN 183 +L +G + + LW + T+ + + H +N + +SP+G++L SA + + K+W+ Sbjct: 1011 QLAAGDEQGNLTLWNFDGTLIRS----IVAHGDRLNQLQYSPNGKYLLSAGREGTAKIWS 1066 Query: 184 GITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVY 363 + G+ + + + QI+ S DS+ + + + D +++WD + L+ + + + Sbjct: 1067 -VEGQLLHTLKSDPLPIDQIAISPDSQWIATAASDGMVRLWD-QQGNLRGEFTSTSGSLL 1124 Query: 364 AVDWSPDGEKVVSGGKDRALKLW 432 +D++ G+ +++ ++ L+ W Sbjct: 1125 GLDFNRQGQWLLAVAQNGDLQSW 1147 Score = 43.1 bits (100), Expect = 6e-04 Identities = 25/109 (22%), Positives = 48/109 (44%) Frame = +1 Query: 106 VNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSK 285 + V P LA+ ++ LWN G + + H + Q+ +S + + LLS + Sbjct: 1000 IRSVSLHPTLPQLAAGDEQGNLTLWN-FDGTLIRSIVAHGDRLNQLQYSPNGKYLLSAGR 1058 Query: 286 DSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 + T K+W + +L L + + SPD + + + D ++LW Sbjct: 1059 EGTAKIWSVEG-QLLHTLKSDPLPIDQIAISPDSQWIATAASDGMVRLW 1106 Score = 38.1 bits (87), Expect = 0.020 Identities = 23/104 (22%), Positives = 48/104 (46%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 L+S + T +W ++ Q + ++ + SPD QW+A+A+ D V+LW+ Sbjct: 1053 LLSAGREGTAKIW--SVEGQLLHTLKSDPLPIDQIAISPDSQWIATAASDGMVRLWDQ-Q 1109 Query: 193 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARK 324 G F + + ++ + LL+ +++ L+ W + K Sbjct: 1110 GNLRGEFTSTSGSLLGLDFNRQGQWLLAVAQNGDLQSWPVTPEK 1153
>TAF5_HUMAN (Q15542) Transcription initiation factor TFIID subunit 5| (Transcription initiation factor TFIID 100 kDa subunit) (TAF(II)100) (TAFII-100) (TAFII100) Length = 800 Score = 92.4 bits (228), Expect = 9e-19 Identities = 48/139 (34%), Positives = 75/139 (53%) Frame = +1 Query: 16 VSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITG 195 VSG D LW T QP GH VN F P+ ++A+ S D++V+LW+ + G Sbjct: 601 VSGGHDRVARLWA-TDHYQPLRIFAGHLADVNCTRFHPNSNYVATGSADRTVRLWDVLNG 659 Query: 196 KFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDW 375 V F GH ++ +++S + R L +G+ D + +WDI + +L GH D V ++ + Sbjct: 660 NCVRIFTGHKGPIHSLTFSPNGRFLATGATDGRVLLWDIGHGLMVGELKGHTDTVCSLRF 719 Query: 376 SPDGEKVVSGGKDRALKLW 432 S DGE + SG D ++LW Sbjct: 720 SRDGEILASGSMDNTVRLW 738 Score = 65.9 bits (159), Expect = 9e-11 Identities = 38/109 (34%), Positives = 63/109 (57%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 + +GS D T+ LW+ ++ TGH+ ++ + FSP+G++LA+ + D V LW+ Sbjct: 642 VATGSADRTVRLWD-VLNGNCVRIFTGHKGPIHSLTFSPNGRFLATGATDGRVLLWDIGH 700 Query: 193 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDL 339 G V +GH V + +S D +L SGS D+T+++WD A K +DL Sbjct: 701 GLMVGELKGHTDTVCSLRFSRDGEILASGSMDNTVRLWD--AIKAFEDL 747 Score = 57.0 bits (136), Expect = 4e-08 Identities = 37/140 (26%), Positives = 58/140 (41%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 + G D T+ +W T K + +++ S D ++ + T Sbjct: 485 IAGGFADSTVRVWSVTPKKLRSVKQASDLSLID------------KESDDVLERIMDEKT 532 Query: 193 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVD 372 + GH VY S+S D LLS S+D T+++W ++ GH V+ Sbjct: 533 ASELKILYGHSGPVYGASFSPDRNYLLSSSEDGTVRLWSLQTFTCLVGYKGHNYPVWDTQ 592 Query: 373 WSPDGEKVVSGGKDRALKLW 432 +SP G VSGG DR +LW Sbjct: 593 FSPYGYYFVSGGHDRVARLW 612 Score = 40.8 bits (94), Expect = 0.003 Identities = 27/109 (24%), Positives = 46/109 (42%), Gaps = 31/109 (28%) Frame = +1 Query: 199 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLK---------------- 330 F+ A++G A + + DS L+ G DST++VW + +KL+ Sbjct: 466 FLNAYQGLTA----VDVTDDSSLIAGGFADSTVRVWSVTPKKLRSVKQASDLSLIDKESD 521 Query: 331 ---------------QDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 + L GH+ VY +SPD ++S +D ++LW Sbjct: 522 DVLERIMDEKTASELKILYGHSGPVYGASFSPDRNYLLSSSEDGTVRLW 570
>WD51B_HUMAN (Q8TC44) WD-repeat protein 51B| Length = 478 Score = 91.7 bits (226), Expect = 2e-18 Identities = 60/179 (33%), Positives = 91/179 (50%), Gaps = 4/179 (2%) Frame = +1 Query: 10 RLVSGSDDFTMFLWEPTISKQPKARM---TGHQKVVNHVYFSPDGQWLASASFDKSVKLW 180 +L + S D + LW + +P AR GH+ VV V FSP G LASAS D++V+LW Sbjct: 32 QLATASWDTFLMLW----NFKPHARAYRYVGHKDVVTSVQFSPHGNLLASASRDRTVRLW 87 Query: 181 -NGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADE 357 GKF + F+ H A V + +SAD + L + S+D ++KVW + ++ L H Sbjct: 88 IPDKRGKF-SEFKAHTAPVRSVDFSADGQFLATASEDKSIKVWSMYRQRFLYSLYRHTHW 146 Query: 358 VYAVDWSPDGEKVVSGGKDRALKLWMN*ACL*YHHECY*DDKCDDQFIEHVDDGVG*AS 534 V +SPDG +VS +D+ +K+W D + Q + + D VG A+ Sbjct: 147 VRCAKFSPDGRLIVSCSEDKTIKIW---------------DTTNKQCVNNFSDSVGFAN 190 Score = 86.3 bits (212), Expect = 7e-17 Identities = 50/141 (35%), Positives = 76/141 (53%), Gaps = 1/141 (0%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPK-ARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGI 189 L S S D T+ LW P K+ K + H V V FS DGQ+LA+AS DKS+K+W+ Sbjct: 75 LASASRDRTVRLWIP--DKRGKFSEFKAHTAPVRSVDFSADGQFLATASEDKSIKVWSMY 132 Query: 190 TGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAV 369 +F+ + H V +S D RL++S S+D T+K+WD ++ + V Sbjct: 133 RQRFLYSLYRHTHWVRCAKFSPDGRLIVSCSEDKTIKIWDTTNKQCVNNFSDSVGFANFV 192 Query: 370 DWSPDGEKVVSGGKDRALKLW 432 D++P G + S G D+ +K+W Sbjct: 193 DFNPSGTCIASAGSDQTVKVW 213 Score = 82.8 bits (203), Expect = 7e-16 Identities = 48/140 (34%), Positives = 73/140 (52%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 +VS S+D T+ +W+ T +KQ + N V F+P G +ASA D++VK+W+ Sbjct: 159 IVSCSEDKTIKIWDTT-NKQCVNNFSDSVGFANFVDFNPSGTCIASAGSDQTVKVWDVRV 217 Query: 193 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVD 372 K + ++ H V IS+ L++ S D TLK+ D+ +L L GH V+ V Sbjct: 218 NKLLQHYQVHSGGVNCISFHPSGNYLITASSDGTLKILDLLEGRLIYTLQGHTGPVFTVS 277 Query: 373 WSPDGEKVVSGGKDRALKLW 432 +S GE SGG D + LW Sbjct: 278 FSKGGELFASGGADTQVLLW 297 Score = 69.3 bits (168), Expect = 8e-12 Identities = 35/114 (30%), Positives = 61/114 (53%) Frame = +1 Query: 91 GHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLL 270 GH+ + + SP+G+ LA+AS+D + LWN + GH V + +S LL Sbjct: 16 GHKAAITSLDLSPNGKQLATASWDTFLMLWNFKPHARAYRYVGHKDVVTSVQFSPHGNLL 75 Query: 271 LSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 S S+D T+++W R + H V +VD+S DG+ + + +D+++K+W Sbjct: 76 ASASRDRTVRLWIPDKRGKFSEFKAHTAPVRSVDFSADGQFLATASEDKSIKVW 129 Score = 50.8 bits (120), Expect = 3e-06 Identities = 23/75 (30%), Positives = 40/75 (53%) Frame = +1 Query: 211 FRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGE 390 F+GH A + + S + + L + S D+ L +W+ + GH D V +V +SP G Sbjct: 14 FKGHKAAITSLDLSPNGKQLATASWDTFLMLWNFKPHARAYRYVGHKDVVTSVQFSPHGN 73 Query: 391 KVVSGGKDRALKLWM 435 + S +DR ++LW+ Sbjct: 74 LLASASRDRTVRLWI 88
>WD51B_PONPY (Q5RD06) WD-repeat protein 51B| Length = 451 Score = 91.7 bits (226), Expect = 2e-18 Identities = 60/179 (33%), Positives = 91/179 (50%), Gaps = 4/179 (2%) Frame = +1 Query: 10 RLVSGSDDFTMFLWEPTISKQPKARM---TGHQKVVNHVYFSPDGQWLASASFDKSVKLW 180 +L + S D + LW + +P AR GH+ VV V FSP G LASAS D++V+LW Sbjct: 32 QLATASWDTFLMLW----NFKPHARAYRYVGHKDVVTSVQFSPHGNLLASASRDRTVRLW 87 Query: 181 -NGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADE 357 GKF + F+ H A V + +SAD + L + S+D ++KVW + ++ L H Sbjct: 88 IPDKRGKF-SEFKAHTAPVRSVDFSADGQFLATASEDKSIKVWSMYRQRFLYSLYRHTHW 146 Query: 358 VYAVDWSPDGEKVVSGGKDRALKLWMN*ACL*YHHECY*DDKCDDQFIEHVDDGVG*AS 534 V +SPDG +VS +D+ +K+W D + Q + + D VG A+ Sbjct: 147 VRCAKFSPDGRLIVSCSEDKTIKIW---------------DTTNKQCVNNFSDSVGFAN 190 Score = 86.3 bits (212), Expect = 7e-17 Identities = 50/141 (35%), Positives = 76/141 (53%), Gaps = 1/141 (0%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPK-ARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGI 189 L S S D T+ LW P K+ K + H V V FS DGQ+LA+AS DKS+K+W+ Sbjct: 75 LASASRDRTVRLWIP--DKRGKFSEFKAHTAPVRSVDFSADGQFLATASEDKSIKVWSMY 132 Query: 190 TGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAV 369 +F+ + H V +S D RL++S S+D T+K+WD ++ + V Sbjct: 133 RQRFLYSLYRHTHWVRCAKFSPDGRLIVSCSEDKTIKIWDTTNKQCVNNFSDSVGFANFV 192 Query: 370 DWSPDGEKVVSGGKDRALKLW 432 D++P G + S G D+ +K+W Sbjct: 193 DFNPSGTCIASAGSDQTVKVW 213 Score = 82.4 bits (202), Expect = 9e-16 Identities = 48/140 (34%), Positives = 73/140 (52%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 +VS S+D T+ +W+ T +KQ + N V F+P G +ASA D++VK+W+ Sbjct: 159 IVSCSEDKTIKIWDTT-NKQCVNNFSDSVGFANFVDFNPSGTCIASAGSDQTVKVWDVRV 217 Query: 193 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVD 372 K + ++ H V IS+ L++ S D TLK+ D+ +L L GH V+ V Sbjct: 218 NKLLQHYQVHSGGVNCISFHPSDNYLVTASSDGTLKILDLLEGRLIYTLQGHTGPVFTVS 277 Query: 373 WSPDGEKVVSGGKDRALKLW 432 +S GE SGG D + LW Sbjct: 278 FSKGGELFASGGADTQVLLW 297 Score = 69.3 bits (168), Expect = 8e-12 Identities = 35/114 (30%), Positives = 61/114 (53%) Frame = +1 Query: 91 GHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLL 270 GH+ + + SP+G+ LA+AS+D + LWN + GH V + +S LL Sbjct: 16 GHKAAITSLDLSPNGKQLATASWDTFLMLWNFKPHARAYRYVGHKDVVTSVQFSPHGNLL 75 Query: 271 LSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 S S+D T+++W R + H V +VD+S DG+ + + +D+++K+W Sbjct: 76 ASASRDRTVRLWIPDKRGKFSEFKAHTAPVRSVDFSADGQFLATASEDKSIKVW 129 Score = 50.8 bits (120), Expect = 3e-06 Identities = 23/75 (30%), Positives = 40/75 (53%) Frame = +1 Query: 211 FRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGE 390 F+GH A + + S + + L + S D+ L +W+ + GH D V +V +SP G Sbjct: 14 FKGHKAAITSLDLSPNGKQLATASWDTFLMLWNFKPHARAYRYVGHKDVVTSVQFSPHGN 73 Query: 391 KVVSGGKDRALKLWM 435 + S +DR ++LW+ Sbjct: 74 LLASASRDRTVRLWI 88
>SWD3_SCHPO (O43017) Set1 complex component swd3 (Set1C component swd3)| (COMPASS component swd3) (Complex proteins associated with set1 protein swd3) Length = 380 Score = 91.7 bits (226), Expect = 2e-18 Identities = 39/114 (34%), Positives = 68/114 (59%) Frame = +1 Query: 91 GHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLL 270 GH+K V V SP+ +W+A++S D ++K+W+ +T + GH + Q+ W+ S+ L Sbjct: 52 GHEKSVTCVSVSPNKRWIATSSSDGTIKIWSALTFRLECTLFGHYRGISQVKWATGSKYL 111 Query: 271 LSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 S S D T+++WD R + L GH + V ++D++P G +VSG D +++W Sbjct: 112 ASASDDKTIRIWDFEKRCSVRCLKGHTNYVSSIDFNPLGTLLVSGSWDETVRIW 165 Score = 72.8 bits (177), Expect = 7e-13 Identities = 37/140 (26%), Positives = 76/140 (54%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 + + S D T+ +W ++ + + + GH + ++ V ++ ++LASAS DK++++W+ Sbjct: 69 IATSSSDGTIKIWS-ALTFRLECTLFGHYRGISQVKWATGSKYLASASDDKTIRIWDFEK 127 Query: 193 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVD 372 V +GH V I ++ LL+SGS D T+++W+++ + LP H++ + +V Sbjct: 128 RCSVRCLKGHTNYVSSIDFNPLGTLLVSGSWDETVRIWNLQDGTCLRMLPAHSEPIISVS 187 Query: 373 WSPDGEKVVSGGKDRALKLW 432 S DG + D ++W Sbjct: 188 ISADGTLCATASYDGMARIW 207 Score = 61.2 bits (147), Expect = 2e-09 Identities = 33/101 (32%), Positives = 53/101 (52%), Gaps = 1/101 (0%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKAR-MTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGI 189 L S SDD T+ +W+ K+ R + GH V+ + F+P G L S S+D++V++WN Sbjct: 111 LASASDDKTIRIWD--FEKRCSVRCLKGHTNYVSSIDFNPLGTLLVSGSWDETVRIWNLQ 168 Query: 190 TGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDI 312 G + H + +S SAD L + S D ++WD+ Sbjct: 169 DGTCLRMLPAHSEPIISVSISADGTLCATASYDGMARIWDV 209 Score = 49.7 bits (117), Expect = 7e-06 Identities = 31/123 (25%), Positives = 62/123 (50%), Gaps = 2/123 (1%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMT-GHQKVVNHVYFSPDGQWLASASFDKSVKLWNGI 189 LVSGS D T+ +W + RM H + + V S DG A+AS+D ++W+ + Sbjct: 153 LVSGSWDETVRIWN--LQDGTCLRMLPAHSEPIISVSISADGTLCATASYDGMARIWDVL 210 Query: 190 TGKFV-TAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYA 366 +G+ + T + + ++ + + LL + +S +++WD R ++ + H + Y+ Sbjct: 211 SGQCLKTLVEPINVPLSNLQFTENRKYLLVSNLNSQIRLWDYRRNRVVRIFDSHVNTRYS 270 Query: 367 VDW 375 + W Sbjct: 271 MSW 273 Score = 34.7 bits (78), Expect = 0.23 Identities = 26/139 (18%), Positives = 58/139 (41%), Gaps = 30/139 (21%) Frame = +1 Query: 106 VNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADS-------- 261 ++++ F+ + ++L ++ + ++LW+ + V F HV Y +SW S Sbjct: 226 LSNLQFTENRKYLLVSNLNSQIRLWDYRRNRVVRIFDSHVNTRYSMSWDCYSSKNIPKNT 285 Query: 262 --------------------RLLLSGSKDSTLKVWDIRARKLKQDLPGHAD--EVYAVDW 375 LL S+D T+++ D + + D H+D E ++ Sbjct: 286 EALPNNDSSYPDDAESFMHDAYLLIPSEDGTIQITDPSTKIIIDDSIRHSDDPETSLLNV 345 Query: 376 SPDGEKVVSGGKDRALKLW 432 + G +++ G D +++W Sbjct: 346 TSLGPFIITSGTDPYVRVW 364
>WD51B_MOUSE (Q8BHD1) WD-repeat protein 51B| Length = 476 Score = 91.3 bits (225), Expect = 2e-18 Identities = 57/178 (32%), Positives = 90/178 (50%), Gaps = 3/178 (1%) Frame = +1 Query: 10 RLVSGSDDFTMFLWEPTISKQPKARM---TGHQKVVNHVYFSPDGQWLASASFDKSVKLW 180 ++ + S D + LW S +P AR GH+ VV + FSP G LASAS D++V+LW Sbjct: 32 QIATASWDTFLMLW----SLKPHARAYRYVGHKDVVTSLQFSPQGNLLASASRDRTVRLW 87 Query: 181 NGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEV 360 + F+ H A V + +SAD +LL++ S+D ++KVW + ++ L H V Sbjct: 88 VLDRKGKSSEFKAHTAPVRSVDFSADGQLLVTASEDKSIKVWSMFRQRFLYSLYRHTHWV 147 Query: 361 YAVDWSPDGEKVVSGGKDRALKLWMN*ACL*YHHECY*DDKCDDQFIEHVDDGVG*AS 534 +SPDG +VS +D+ +K+W D + Q + + D VG A+ Sbjct: 148 RCAKFSPDGRLIVSCSEDKTIKIW---------------DTTNKQCVNNFSDSVGFAN 190 Score = 84.0 bits (206), Expect = 3e-16 Identities = 48/140 (34%), Positives = 72/140 (51%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 L S S D T+ LW K + H V V FS DGQ L +AS DKS+K+W+ Sbjct: 75 LASASRDRTVRLWVLD-RKGKSSEFKAHTAPVRSVDFSADGQLLVTASEDKSIKVWSMFR 133 Query: 193 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVD 372 +F+ + H V +S D RL++S S+D T+K+WD ++ + VD Sbjct: 134 QRFLYSLYRHTHWVRCAKFSPDGRLIVSCSEDKTIKIWDTTNKQCVNNFSDSVGFANFVD 193 Query: 373 WSPDGEKVVSGGKDRALKLW 432 ++P+G + S G D A+K+W Sbjct: 194 FNPNGTCIASAGSDHAVKIW 213 Score = 79.3 bits (194), Expect = 8e-15 Identities = 46/140 (32%), Positives = 75/140 (53%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 +VS S+D T+ +W+ T +KQ + N V F+P+G +ASA D +VK+W+ Sbjct: 159 IVSCSEDKTIKIWDTT-NKQCVNNFSDSVGFANFVDFNPNGTCIASAGSDHAVKIWDIRM 217 Query: 193 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVD 372 K + ++ H V +S+ L++ S D T+K+ D+ +L L GH V+ V Sbjct: 218 NKLLQHYQVHSCGVNCLSFHPLGNSLVTASSDGTVKMLDLIEGRLIYTLQGHTGPVFTVS 277 Query: 373 WSPDGEKVVSGGKDRALKLW 432 +S DGE + SGG D + +W Sbjct: 278 FSKDGELLTSGGADAQVLIW 297 Score = 68.6 bits (166), Expect = 1e-11 Identities = 33/114 (28%), Positives = 62/114 (54%) Frame = +1 Query: 91 GHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLL 270 GH+ + FSP+ + +A+AS+D + LW+ + GH V + +S LL Sbjct: 16 GHKAAITSADFSPNCKQIATASWDTFLMLWSLKPHARAYRYVGHKDVVTSLQFSPQGNLL 75 Query: 271 LSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 S S+D T+++W + + + H V +VD+S DG+ +V+ +D+++K+W Sbjct: 76 ASASRDRTVRLWVLDRKGKSSEFKAHTAPVRSVDFSADGQLLVTASEDKSIKVW 129 Score = 65.9 bits (159), Expect = 9e-11 Identities = 38/139 (27%), Positives = 67/139 (48%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 LV+ S+D ++ +W ++ + H V FSPDG+ + S S DK++K+W+ Sbjct: 117 LVTASEDKSIKVWS-MFRQRFLYSLYRHTHWVRCAKFSPDGRLIVSCSEDKTIKIWDTTN 175 Query: 193 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVD 372 + V F V + ++ + + S D +K+WDIR KL Q H+ V + Sbjct: 176 KQCVNNFSDSVGFANFVDFNPNGTCIASAGSDHAVKIWDIRMNKLLQHYQVHSCGVNCLS 235 Query: 373 WSPDGEKVVSGGKDRALKL 429 + P G +V+ D +K+ Sbjct: 236 FHPLGNSLVTASSDGTVKM 254 Score = 49.7 bits (117), Expect = 7e-06 Identities = 21/76 (27%), Positives = 41/76 (53%) Frame = +1 Query: 208 AFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDG 387 +F+GH A + +S + + + + S D+ L +W ++ GH D V ++ +SP G Sbjct: 13 SFKGHKAAITSADFSPNCKQIATASWDTFLMLWSLKPHARAYRYVGHKDVVTSLQFSPQG 72 Query: 388 EKVVSGGKDRALKLWM 435 + S +DR ++LW+ Sbjct: 73 NLLASASRDRTVRLWV 88
>GBLP_BRARE (O42248) Guanine nucleotide-binding protein beta subunit 2-like 1| (Receptor of activated protein kinase C) (RACK) Length = 317 Score = 91.3 bits (225), Expect = 2e-18 Identities = 51/150 (34%), Positives = 84/150 (56%), Gaps = 7/150 (4%) Frame = +1 Query: 4 PXRLVSGSDDFTMFLWEPTISKQ----PKARMTGHQKVVNHVYFSPDGQWLASASFDKSV 171 P ++S S D T+ +W+ T + P+ + GH V+ V S DGQ+ S S+D ++ Sbjct: 28 PDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDVVISSDGQFALSGSWDGTL 87 Query: 172 KLWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWD-IRARKLKQDLPGH 348 +LW+ TG F GH DV +++SAD+R ++SGS+D T+K+W+ + K H Sbjct: 88 RLWDLTTGTTTRRFVGHTKDVLSVAFSADNRQIVSGSRDKTIKLWNTLGVCKYTIQDDSH 147 Query: 349 ADEVYAVDWSPDGEK--VVSGGKDRALKLW 432 + V V +SP+ +VS G D+ +K+W Sbjct: 148 TEWVSCVRFSPNSSNPIIVSCGWDKMVKVW 177 Score = 59.3 bits (142), Expect = 9e-09 Identities = 41/127 (32%), Positives = 61/127 (48%), Gaps = 2/127 (1%) Frame = +1 Query: 10 RLVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQ--WLASASFDKSVKLWN 183 ++VSGS D T+ LW + + H + V+ V FSP+ + S +DK VK+WN Sbjct: 119 QIVSGSRDKTIKLWNTLGVCKYTIQDDSHTEWVSCVRFSPNSSNPIIVSCGWDKMVKVWN 178 Query: 184 GITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVY 363 K T GH + ++ S D L SG KD +WD+ K L G D + Sbjct: 179 LANCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDG-GDTIN 237 Query: 364 AVDWSPD 384 A+ +SP+ Sbjct: 238 ALCFSPN 244 Score = 44.3 bits (103), Expect = 3e-04 Identities = 29/108 (26%), Positives = 49/108 (45%), Gaps = 10/108 (9%) Frame = +1 Query: 19 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 198 SG D LW+ K G +N + FSP+ WL +A+ S+K+W+ + GK Sbjct: 209 SGGKDGQAMLWDLNEGKHLYTLDGGD--TINALCFSPNRYWLCAAT-GPSIKIWD-LEGK 264 Query: 199 FV----------TAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDI 312 + T + ++WSAD + L +G D+ ++VW + Sbjct: 265 IIVDELRQDIITTNSKAEPPQCTSLAWSADGQTLFAGYTDNLIRVWQV 312
>TAF5_MOUSE (Q8C092) Transcription initiation factor TFIID subunit 5| (Transcription initiation factor TFIID 100 kDa subunit) (TAF(II)100) (TAFII-100) (TAFII100) Length = 801 Score = 91.3 bits (225), Expect = 2e-18 Identities = 47/139 (33%), Positives = 75/139 (53%) Frame = +1 Query: 16 VSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITG 195 VSG D LW T QP GH VN + P+ ++A+ S D++V+LW+ + G Sbjct: 602 VSGGHDRVARLWA-TDHYQPLRIFAGHLADVNCTRYHPNSNYVATGSADRTVRLWDVLNG 660 Query: 196 KFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDW 375 V F GH ++ +++S + R L +G+ D + +WDI + +L GH D V ++ + Sbjct: 661 NCVRIFTGHKGPIHSLTFSPNGRFLATGATDGRVLLWDIGHGLMVGELKGHTDTVCSLRF 720 Query: 376 SPDGEKVVSGGKDRALKLW 432 S DGE + SG D ++LW Sbjct: 721 SRDGEILASGSMDNTVRLW 739 Score = 65.9 bits (159), Expect = 9e-11 Identities = 38/109 (34%), Positives = 63/109 (57%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 + +GS D T+ LW+ ++ TGH+ ++ + FSP+G++LA+ + D V LW+ Sbjct: 643 VATGSADRTVRLWD-VLNGNCVRIFTGHKGPIHSLTFSPNGRFLATGATDGRVLLWDIGH 701 Query: 193 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDL 339 G V +GH V + +S D +L SGS D+T+++WD A K +DL Sbjct: 702 GLMVGELKGHTDTVCSLRFSRDGEILASGSMDNTVRLWD--AVKAFEDL 748 Score = 57.0 bits (136), Expect = 4e-08 Identities = 37/140 (26%), Positives = 58/140 (41%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 + G D T+ +W T K + +++ S D ++ + T Sbjct: 486 IAGGFADSTVRVWSVTPKKLRSVKQASDLSLID------------KESDDVLERIMDEKT 533 Query: 193 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVD 372 + GH VY S+S D LLS S+D T+++W ++ GH V+ Sbjct: 534 ASELKILYGHSGPVYGASFSPDRNYLLSSSEDGTVRLWSLQTFTCLVGYKGHNYPVWDTQ 593 Query: 373 WSPDGEKVVSGGKDRALKLW 432 +SP G VSGG DR +LW Sbjct: 594 FSPYGYYFVSGGHDRVARLW 613 Score = 40.8 bits (94), Expect = 0.003 Identities = 27/109 (24%), Positives = 46/109 (42%), Gaps = 31/109 (28%) Frame = +1 Query: 199 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLK---------------- 330 F+ A++G A + + DS L+ G DST++VW + +KL+ Sbjct: 467 FLNAYQGLTA----VDVTDDSSLIAGGFADSTVRVWSVTPKKLRSVKQASDLSLIDKESD 522 Query: 331 ---------------QDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 + L GH+ VY +SPD ++S +D ++LW Sbjct: 523 DVLERIMDEKTASELKILYGHSGPVYGASFSPDRNYLLSSSEDGTVRLW 571
>PRP4_YEAST (P20053) U4/U6 small nuclear ribonucleoprotein PRP4| Length = 465 Score = 90.9 bits (224), Expect = 3e-18 Identities = 40/116 (34%), Positives = 67/116 (57%) Frame = +1 Query: 85 MTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSR 264 + GH++ ++ V + P G+++ SAS D + +LW+ T + + GH V+ +S+ D Sbjct: 261 LVGHERRISDVKYHPSGKFIGSASHDMTWRLWDASTHQELLLQEGHDKGVFSLSFQCDGS 320 Query: 265 LLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 L+ SG DS +WDIR+ L GH+ +Y V WSP+G +V +GG D + +W Sbjct: 321 LVCSGGMDSLSMLWDIRSGSKVMTLAGHSKPIYTVAWSPNGYQVATGGGDGIINVW 376 Score = 70.5 bits (171), Expect = 4e-12 Identities = 49/184 (26%), Positives = 71/184 (38%), Gaps = 46/184 (25%) Frame = +1 Query: 19 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 198 S S D T LW+ + + Q GH K V + F DG + S D LW+ +G Sbjct: 282 SASHDMTWRLWDAS-THQELLLQEGHDKGVFSLSFQCDGSLVCSGGMDSLSMLWDIRSGS 340 Query: 199 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQ--------------- 333 V GH +Y ++WS + + +G D + VWDIR R Q Sbjct: 341 KVMTLAGHSKPIYTVAWSPNGYQVATGGGDGIINVWDIRKRDEGQLNQILAHRNIVTQVR 400 Query: 334 -------------------------------DLPGHADEVYAVDWSPDGEKVVSGGKDRA 420 L GH D++ ++D S + +VSGG DR+ Sbjct: 401 FSKEDGGKKLVSCGYDNLINVYSSDTWLKMGSLAGHTDKIISLDISNNSHFLVSGGWDRS 460 Query: 421 LKLW 432 +KLW Sbjct: 461 IKLW 464 Score = 43.1 bits (100), Expect = 6e-04 Identities = 25/105 (23%), Positives = 54/105 (51%), Gaps = 5/105 (4%) Frame = +1 Query: 10 RLVSGSDDFTMFLWEPTISKQPKARMT---GHQKVVNHVYFSPD--GQWLASASFDKSVK 174 ++ +G D + +W+ I K+ + ++ H+ +V V FS + G+ L S +D + Sbjct: 363 QVATGGGDGIINVWD--IRKRDEGQLNQILAHRNIVTQVRFSKEDGGKKLVSCGYDNLIN 420 Query: 175 LWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWD 309 +++ T + + GH + + S +S L+SG D ++K+W+ Sbjct: 421 VYSSDTWLKMGSLAGHTDKIISLDISNNSHFLVSGGWDRSIKLWN 465 Score = 38.1 bits (87), Expect = 0.020 Identities = 30/117 (25%), Positives = 53/117 (45%), Gaps = 6/117 (5%) Frame = +1 Query: 100 KVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTA-FRGHVADVYQISWSADSR-LLL 273 K ++ V S D +A+ S+ +++ N T + +T HV + I W DS ++ Sbjct: 176 KPISAVSLSTDDMVVATGSWAGDLQVLNSQTLQPLTQKLDSHVGKIGAIDWHPDSNNQMI 235 Query: 274 SGSKDSTLKVWDIRAR----KLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 S ++D +K + +L DL GH + V + P G+ + S D +LW Sbjct: 236 SCAEDGLIKNFQYSNEEGGLRLLGDLVGHERRISDVKYHPSGKFIGSASHDMTWRLW 292
>TAF5L_MOUSE (Q91WQ5) TAF5-like RNA polymerase II p300/CBP-associated| factor-associated factor 65 kDa subunit 5L (PCAF-associated factor 65 beta) (PAF65-beta) Length = 589 Score = 90.9 bits (224), Expect = 3e-18 Identities = 48/138 (34%), Positives = 75/138 (54%) Frame = +1 Query: 19 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 198 SGS D T LW + P GH V+ V F P+ +LA+ S DK+V+LW+ G Sbjct: 401 SGSHDRTARLWSFDRT-YPLRIYAGHLADVDCVKFHPNSNYLATGSTDKTVRLWSAQQGN 459 Query: 199 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWS 378 V F GH V +S+S + + L S +D LK+WD+ + L ++L GH D + ++ +S Sbjct: 460 SVRLFTGHRGPVLSLSFSPNGKYLASAGEDQRLKLWDLASGTLFKELRGHTDSITSLAFS 519 Query: 379 PDGEKVVSGGKDRALKLW 432 PD + S D ++++W Sbjct: 520 PDSGLIASASMDNSVRVW 537 Score = 77.8 bits (190), Expect = 2e-14 Identities = 42/119 (35%), Positives = 66/119 (55%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 L +GS D T+ LW + TGH+ V + FSP+G++LASA D+ +KLW+ + Sbjct: 441 LATGSTDKTVRLWSAQQGNSVRL-FTGHRGPVLSLSFSPNGKYLASAGEDQRLKLWDLAS 499 Query: 193 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAV 369 G RGH + +++S DS L+ S S D++++VWDIR+ G + E+ V Sbjct: 500 GTLFKELRGHTDSITSLAFSPDSGLIASASMDNSVRVWDIRSTCCNTPADGSSGELVGV 558 Score = 54.7 bits (130), Expect = 2e-07 Identities = 31/116 (26%), Positives = 51/116 (43%) Frame = +1 Query: 85 MTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSR 264 + GH V F D L S S D S++ W+ + ++GH V+ + S S Sbjct: 338 LRGHCGPVYSTRFLADSSGLLSCSEDMSIRYWDLGSFTNTVLYQGHAYPVWDVDISPFSL 397 Query: 265 LLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 SGS D T ++W + GH +V V + P+ + +G D+ ++LW Sbjct: 398 YFASGSHDRTARLWSFDRTYPLRIYAGHLADVDCVKFHPNSNYLATGSTDKTVRLW 453 Score = 53.9 bits (128), Expect = 4e-07 Identities = 31/81 (38%), Positives = 41/81 (50%) Frame = +1 Query: 190 TGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAV 369 TG + RGH VY + ADS LLS S+D +++ WD+ + GHA V+ V Sbjct: 331 TGTEMKILRGHCGPVYSTRFLADSSGLLSCSEDMSIRYWDLGSFTNTVLYQGHAYPVWDV 390 Query: 370 DWSPDGEKVVSGGKDRALKLW 432 D SP SG DR +LW Sbjct: 391 DISPFSLYFASGSHDRTARLW 411 Score = 37.0 bits (84), Expect = 0.045 Identities = 16/35 (45%), Positives = 26/35 (74%) Frame = +1 Query: 250 SADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHAD 354 S+DS+LL +G +S +K+W +R++KLK + P H D Sbjct: 277 SSDSKLLAAGFDNSCIKLWSLRSKKLKSE-PHHVD 310
>GBLP_RAT (P63245) Guanine nucleotide-binding protein beta subunit 2-like 1| (Receptor of activated protein kinase C 1) (RACK1) (Receptor for activated C kinase) Length = 316 Score = 90.9 bits (224), Expect = 3e-18 Identities = 50/150 (33%), Positives = 85/150 (56%), Gaps = 7/150 (4%) Frame = +1 Query: 4 PXRLVSGSDDFTMFLWEPTISKQ----PKARMTGHQKVVNHVYFSPDGQWLASASFDKSV 171 P ++S S D T+ +W+ T + P+ + GH V+ V S DGQ+ S S+D ++ Sbjct: 27 PDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDVVISSDGQFALSGSWDGTL 86 Query: 172 KLWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWD-IRARKLKQDLPGH 348 +LW+ TG F GH DV +++S+D+R ++SGS+D T+K+W+ + K H Sbjct: 87 RLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLWNTLGVCKYTVQDESH 146 Query: 349 ADEVYAVDWSPDGEK--VVSGGKDRALKLW 432 ++ V V +SP+ +VS G D+ +K+W Sbjct: 147 SEWVSCVRFSPNSSNPIIVSCGWDKLVKVW 176 Score = 58.9 bits (141), Expect = 1e-08 Identities = 41/127 (32%), Positives = 61/127 (48%), Gaps = 2/127 (1%) Frame = +1 Query: 10 RLVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQ--WLASASFDKSVKLWN 183 ++VSGS D T+ LW + + H + V+ V FSP+ + S +DK VK+WN Sbjct: 118 QIVSGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWN 177 Query: 184 GITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVY 363 K T GH + ++ S D L SG KD +WD+ K L G D + Sbjct: 178 LANCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDG-GDIIN 236 Query: 364 AVDWSPD 384 A+ +SP+ Sbjct: 237 ALCFSPN 243 Score = 46.2 bits (108), Expect = 7e-05 Identities = 29/108 (26%), Positives = 51/108 (47%), Gaps = 10/108 (9%) Frame = +1 Query: 19 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 198 SG D LW+ K G ++N + FSP+ WL +A+ S+K+W+ + GK Sbjct: 208 SGGKDGQAMLWDLNEGKHLYTLDGGD--IINALCFSPNRYWLCAAT-GPSIKIWD-LEGK 263 Query: 199 FV----------TAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDI 312 + T+ + ++WSAD + L +G D+ ++VW + Sbjct: 264 IIVDELKQEVISTSSKAEPPQCTSLAWSADGQTLFAGYTDNLVRVWQV 311
>GBLP_PIG (P63246) Guanine nucleotide-binding protein beta subunit 2-like 1| (Receptor of activated protein kinase C 1) (RACK1) (Receptor for activated C kinase) Length = 316 Score = 90.9 bits (224), Expect = 3e-18 Identities = 50/150 (33%), Positives = 85/150 (56%), Gaps = 7/150 (4%) Frame = +1 Query: 4 PXRLVSGSDDFTMFLWEPTISKQ----PKARMTGHQKVVNHVYFSPDGQWLASASFDKSV 171 P ++S S D T+ +W+ T + P+ + GH V+ V S DGQ+ S S+D ++ Sbjct: 27 PDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDVVISSDGQFALSGSWDGTL 86 Query: 172 KLWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWD-IRARKLKQDLPGH 348 +LW+ TG F GH DV +++S+D+R ++SGS+D T+K+W+ + K H Sbjct: 87 RLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLWNTLGVCKYTVQDESH 146 Query: 349 ADEVYAVDWSPDGEK--VVSGGKDRALKLW 432 ++ V V +SP+ +VS G D+ +K+W Sbjct: 147 SEWVSCVRFSPNSSNPIIVSCGWDKLVKVW 176 Score = 58.9 bits (141), Expect = 1e-08 Identities = 41/127 (32%), Positives = 61/127 (48%), Gaps = 2/127 (1%) Frame = +1 Query: 10 RLVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQ--WLASASFDKSVKLWN 183 ++VSGS D T+ LW + + H + V+ V FSP+ + S +DK VK+WN Sbjct: 118 QIVSGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWN 177 Query: 184 GITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVY 363 K T GH + ++ S D L SG KD +WD+ K L G D + Sbjct: 178 LANCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDG-GDIIN 236 Query: 364 AVDWSPD 384 A+ +SP+ Sbjct: 237 ALCFSPN 243 Score = 46.2 bits (108), Expect = 7e-05 Identities = 29/108 (26%), Positives = 51/108 (47%), Gaps = 10/108 (9%) Frame = +1 Query: 19 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 198 SG D LW+ K G ++N + FSP+ WL +A+ S+K+W+ + GK Sbjct: 208 SGGKDGQAMLWDLNEGKHLYTLDGGD--IINALCFSPNRYWLCAAT-GPSIKIWD-LEGK 263 Query: 199 FV----------TAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDI 312 + T+ + ++WSAD + L +G D+ ++VW + Sbjct: 264 IIVDELKQEVISTSSKAEPPQCTSLAWSADGQTLFAGYTDNLVRVWQV 311
>GBLP_MOUSE (P68040) Guanine nucleotide-binding protein beta subunit 2-like 1| (Receptor of activated protein kinase C 1) (RACK1) (Receptor for activated C kinase) (p205) (12-3) Length = 316 Score = 90.9 bits (224), Expect = 3e-18 Identities = 50/150 (33%), Positives = 85/150 (56%), Gaps = 7/150 (4%) Frame = +1 Query: 4 PXRLVSGSDDFTMFLWEPTISKQ----PKARMTGHQKVVNHVYFSPDGQWLASASFDKSV 171 P ++S S D T+ +W+ T + P+ + GH V+ V S DGQ+ S S+D ++ Sbjct: 27 PDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDVVISSDGQFALSGSWDGTL 86 Query: 172 KLWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWD-IRARKLKQDLPGH 348 +LW+ TG F GH DV +++S+D+R ++SGS+D T+K+W+ + K H Sbjct: 87 RLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLWNTLGVCKYTVQDESH 146 Query: 349 ADEVYAVDWSPDGEK--VVSGGKDRALKLW 432 ++ V V +SP+ +VS G D+ +K+W Sbjct: 147 SEWVSCVRFSPNSSNPIIVSCGWDKLVKVW 176 Score = 58.9 bits (141), Expect = 1e-08 Identities = 41/127 (32%), Positives = 61/127 (48%), Gaps = 2/127 (1%) Frame = +1 Query: 10 RLVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQ--WLASASFDKSVKLWN 183 ++VSGS D T+ LW + + H + V+ V FSP+ + S +DK VK+WN Sbjct: 118 QIVSGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWN 177 Query: 184 GITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVY 363 K T GH + ++ S D L SG KD +WD+ K L G D + Sbjct: 178 LANCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDG-GDIIN 236 Query: 364 AVDWSPD 384 A+ +SP+ Sbjct: 237 ALCFSPN 243 Score = 46.2 bits (108), Expect = 7e-05 Identities = 29/108 (26%), Positives = 51/108 (47%), Gaps = 10/108 (9%) Frame = +1 Query: 19 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 198 SG D LW+ K G ++N + FSP+ WL +A+ S+K+W+ + GK Sbjct: 208 SGGKDGQAMLWDLNEGKHLYTLDGGD--IINALCFSPNRYWLCAAT-GPSIKIWD-LEGK 263 Query: 199 FV----------TAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDI 312 + T+ + ++WSAD + L +G D+ ++VW + Sbjct: 264 IIVDELKQEVISTSSKAEPPQCTSLAWSADGQTLFAGYTDNLVRVWQV 311
>GBLP_MACFA (Q4R7Y4) Guanine nucleotide-binding protein beta subunit 2-like 1| Length = 316 Score = 90.9 bits (224), Expect = 3e-18 Identities = 50/150 (33%), Positives = 85/150 (56%), Gaps = 7/150 (4%) Frame = +1 Query: 4 PXRLVSGSDDFTMFLWEPTISKQ----PKARMTGHQKVVNHVYFSPDGQWLASASFDKSV 171 P ++S S D T+ +W+ T + P+ + GH V+ V S DGQ+ S S+D ++ Sbjct: 27 PDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDVVISSDGQFALSGSWDGTL 86 Query: 172 KLWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWD-IRARKLKQDLPGH 348 +LW+ TG F GH DV +++S+D+R ++SGS+D T+K+W+ + K H Sbjct: 87 RLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLWNTLGVCKYTVQDESH 146 Query: 349 ADEVYAVDWSPDGEK--VVSGGKDRALKLW 432 ++ V V +SP+ +VS G D+ +K+W Sbjct: 147 SEWVSCVRFSPNSSNPIIVSCGWDKLVKVW 176 Score = 58.9 bits (141), Expect = 1e-08 Identities = 41/127 (32%), Positives = 61/127 (48%), Gaps = 2/127 (1%) Frame = +1 Query: 10 RLVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQ--WLASASFDKSVKLWN 183 ++VSGS D T+ LW + + H + V+ V FSP+ + S +DK VK+WN Sbjct: 118 QIVSGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWN 177 Query: 184 GITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVY 363 K T GH + ++ S D L SG KD +WD+ K L G D + Sbjct: 178 LANCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDG-GDIIN 236 Query: 364 AVDWSPD 384 A+ +SP+ Sbjct: 237 ALCFSPN 243 Score = 46.2 bits (108), Expect = 7e-05 Identities = 29/108 (26%), Positives = 51/108 (47%), Gaps = 10/108 (9%) Frame = +1 Query: 19 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 198 SG D LW+ K G ++N + FSP+ WL +A+ S+K+W+ + GK Sbjct: 208 SGGKDGQAMLWDLNEGKHLYTLDGGD--IINALCFSPNRYWLCAAT-GPSIKIWD-LEGK 263 Query: 199 FV----------TAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDI 312 + T+ + ++WSAD + L +G D+ ++VW + Sbjct: 264 IIVDELKQEVISTSSKAEPPQCTSLAWSADGQTLFAGYTDNLVRVWQV 311
>GBLP_HUMAN (P63244) Guanine nucleotide-binding protein beta subunit 2-like 1| (Guanine nucleotide-binding protein beta subunit-like protein 12.3) (Receptor of activated protein kinase C 1) (RACK1) (Receptor for activated C kinase) Length = 316 Score = 90.9 bits (224), Expect = 3e-18 Identities = 50/150 (33%), Positives = 85/150 (56%), Gaps = 7/150 (4%) Frame = +1 Query: 4 PXRLVSGSDDFTMFLWEPTISKQ----PKARMTGHQKVVNHVYFSPDGQWLASASFDKSV 171 P ++S S D T+ +W+ T + P+ + GH V+ V S DGQ+ S S+D ++ Sbjct: 27 PDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDVVISSDGQFALSGSWDGTL 86 Query: 172 KLWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWD-IRARKLKQDLPGH 348 +LW+ TG F GH DV +++S+D+R ++SGS+D T+K+W+ + K H Sbjct: 87 RLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLWNTLGVCKYTVQDESH 146 Query: 349 ADEVYAVDWSPDGEK--VVSGGKDRALKLW 432 ++ V V +SP+ +VS G D+ +K+W Sbjct: 147 SEWVSCVRFSPNSSNPIIVSCGWDKLVKVW 176 Score = 58.9 bits (141), Expect = 1e-08 Identities = 41/127 (32%), Positives = 61/127 (48%), Gaps = 2/127 (1%) Frame = +1 Query: 10 RLVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQ--WLASASFDKSVKLWN 183 ++VSGS D T+ LW + + H + V+ V FSP+ + S +DK VK+WN Sbjct: 118 QIVSGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWN 177 Query: 184 GITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVY 363 K T GH + ++ S D L SG KD +WD+ K L G D + Sbjct: 178 LANCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDG-GDIIN 236 Query: 364 AVDWSPD 384 A+ +SP+ Sbjct: 237 ALCFSPN 243 Score = 46.2 bits (108), Expect = 7e-05 Identities = 29/108 (26%), Positives = 51/108 (47%), Gaps = 10/108 (9%) Frame = +1 Query: 19 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 198 SG D LW+ K G ++N + FSP+ WL +A+ S+K+W+ + GK Sbjct: 208 SGGKDGQAMLWDLNEGKHLYTLDGGD--IINALCFSPNRYWLCAAT-GPSIKIWD-LEGK 263 Query: 199 FV----------TAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDI 312 + T+ + ++WSAD + L +G D+ ++VW + Sbjct: 264 IIVDELKQEVISTSSKAEPPQCTSLAWSADGQTLFAGYTDNLVRVWQV 311
>GBLP_BOVIN (P63243) Guanine nucleotide-binding protein beta subunit 2-like 1| (Receptor of activated protein kinase C 1) (RACK1) (Receptor for activated C kinase) Length = 316 Score = 90.9 bits (224), Expect = 3e-18 Identities = 50/150 (33%), Positives = 85/150 (56%), Gaps = 7/150 (4%) Frame = +1 Query: 4 PXRLVSGSDDFTMFLWEPTISKQ----PKARMTGHQKVVNHVYFSPDGQWLASASFDKSV 171 P ++S S D T+ +W+ T + P+ + GH V+ V S DGQ+ S S+D ++ Sbjct: 27 PDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDVVISSDGQFALSGSWDGTL 86 Query: 172 KLWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWD-IRARKLKQDLPGH 348 +LW+ TG F GH DV +++S+D+R ++SGS+D T+K+W+ + K H Sbjct: 87 RLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLWNTLGVCKYTVQDESH 146 Query: 349 ADEVYAVDWSPDGEK--VVSGGKDRALKLW 432 ++ V V +SP+ +VS G D+ +K+W Sbjct: 147 SEWVSCVRFSPNSSNPIIVSCGWDKLVKVW 176 Score = 58.9 bits (141), Expect = 1e-08 Identities = 41/127 (32%), Positives = 61/127 (48%), Gaps = 2/127 (1%) Frame = +1 Query: 10 RLVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQ--WLASASFDKSVKLWN 183 ++VSGS D T+ LW + + H + V+ V FSP+ + S +DK VK+WN Sbjct: 118 QIVSGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWN 177 Query: 184 GITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVY 363 K T GH + ++ S D L SG KD +WD+ K L G D + Sbjct: 178 LANCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDG-GDIIN 236 Query: 364 AVDWSPD 384 A+ +SP+ Sbjct: 237 ALCFSPN 243 Score = 46.2 bits (108), Expect = 7e-05 Identities = 29/108 (26%), Positives = 51/108 (47%), Gaps = 10/108 (9%) Frame = +1 Query: 19 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 198 SG D LW+ K G ++N + FSP+ WL +A+ S+K+W+ + GK Sbjct: 208 SGGKDGQAMLWDLNEGKHLYTLDGGD--IINALCFSPNRYWLCAAT-GPSIKIWD-LEGK 263 Query: 199 FV----------TAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDI 312 + T+ + ++WSAD + L +G D+ ++VW + Sbjct: 264 IIVDELKQEVISTSSKAEPPQCTSLAWSADGQTLFAGYTDNLVRVWQV 311
>GBLP_CHICK (P63247) Guanine nucleotide-binding protein beta subunit 2-like 1| (Guanine nucleotide-binding protein beta subunit-like protein 12.3) (Receptor of activated protein kinase C 1) (RACK1) (Receptor for activated C kinase) Length = 317 Score = 90.9 bits (224), Expect = 3e-18 Identities = 50/150 (33%), Positives = 85/150 (56%), Gaps = 7/150 (4%) Frame = +1 Query: 4 PXRLVSGSDDFTMFLWEPTISKQ----PKARMTGHQKVVNHVYFSPDGQWLASASFDKSV 171 P ++S S D T+ +W+ T + P+ + GH V+ V S DGQ+ S S+D ++ Sbjct: 28 PDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDVVISSDGQFALSGSWDGTL 87 Query: 172 KLWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWD-IRARKLKQDLPGH 348 +LW+ TG F GH DV +++S+D+R ++SGS+D T+K+W+ + K H Sbjct: 88 RLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLWNTLGVCKYTVQDESH 147 Query: 349 ADEVYAVDWSPDGEK--VVSGGKDRALKLW 432 ++ V V +SP+ +VS G D+ +K+W Sbjct: 148 SEWVSCVRFSPNSSNPIIVSCGWDKLVKVW 177 Score = 58.9 bits (141), Expect = 1e-08 Identities = 41/127 (32%), Positives = 61/127 (48%), Gaps = 2/127 (1%) Frame = +1 Query: 10 RLVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQ--WLASASFDKSVKLWN 183 ++VSGS D T+ LW + + H + V+ V FSP+ + S +DK VK+WN Sbjct: 119 QIVSGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWN 178 Query: 184 GITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVY 363 K T GH + ++ S D L SG KD +WD+ K L G D + Sbjct: 179 LANCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDG-GDIIN 237 Query: 364 AVDWSPD 384 A+ +SP+ Sbjct: 238 ALCFSPN 244 Score = 46.2 bits (108), Expect = 7e-05 Identities = 29/108 (26%), Positives = 51/108 (47%), Gaps = 10/108 (9%) Frame = +1 Query: 19 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 198 SG D LW+ K G ++N + FSP+ WL +A+ S+K+W+ + GK Sbjct: 209 SGGKDGQAMLWDLNEGKHLYTLDGGD--IINALCFSPNRYWLCAAT-GPSIKIWD-LEGK 264 Query: 199 FV----------TAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDI 312 + T+ + ++WSAD + L +G D+ ++VW + Sbjct: 265 IIVDELKQEVISTSSKAEPPQCTSLAWSADGQTLFAGYTDNLVRVWQV 312
>KTNB1_MOUSE (Q8BG40) Katanin p80 WD40-containing subunit B1 (Katanin p80| subunit B1) (p80 katanin) Length = 658 Score = 90.5 bits (223), Expect = 3e-18 Identities = 50/134 (37%), Positives = 75/134 (55%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 + SGS D + LW+ K R GH + V + FSPDG+WLASA+ D +VKLW+ Sbjct: 120 VASGSQDTNIKLWDIR-RKGCVFRYRGHSQAVRCLRFSPDGKWLASAADDHTVKLWDLTA 178 Query: 193 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVD 372 GK ++ F GH V + + + LL SGS D T++ WD+ ++ + G V +V Sbjct: 179 GKMMSEFPGHTGPVNVVEFHPNEYLLASGSSDRTIRFWDLEKFQVVSCIEGEPGPVRSVL 238 Query: 373 WSPDGEKVVSGGKD 414 ++PDG + SG +D Sbjct: 239 FNPDGCCLYSGCQD 252 Score = 86.7 bits (213), Expect = 5e-17 Identities = 45/140 (32%), Positives = 78/140 (55%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 +V+GS ++ +W+ +K + M GH+ + + F P G+++AS S D ++KLW+ Sbjct: 78 IVAGSQSGSIRVWDLEAAKILRTLM-GHKANICSLDFHPYGEFVASGSQDTNIKLWDIRR 136 Query: 193 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVD 372 V +RGH V + +S D + L S + D T+K+WD+ A K+ + PGH V V+ Sbjct: 137 KGCVFRYRGHSQAVRCLRFSPDGKWLASAADDHTVKLWDLTAGKMMSEFPGHTGPVNVVE 196 Query: 373 WSPDGEKVVSGGKDRALKLW 432 + P+ + SG DR ++ W Sbjct: 197 FHPNEYLLASGSSDRTIRFW 216 Score = 74.7 bits (182), Expect = 2e-13 Identities = 43/142 (30%), Positives = 72/142 (50%), Gaps = 2/142 (1%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARM--TGHQKVVNHVYFSPDGQWLASASFDKSVKLWNG 186 L +G DD + LW +I+K P M TGH V V + + + + S S+++W+ Sbjct: 36 LATGGDDCRVNLW--SINK-PNCIMSLTGHTSPVESVRLNTPEELIVAGSQSGSIRVWDL 92 Query: 187 ITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYA 366 K + GH A++ + + + SGS+D+ +K+WDIR + GH+ V Sbjct: 93 EAAKILRTLMGHKANICSLDFHPYGEFVASGSQDTNIKLWDIRRKGCVFRYRGHSQAVRC 152 Query: 367 VDWSPDGEKVVSGGKDRALKLW 432 + +SPDG+ + S D +KLW Sbjct: 153 LRFSPDGKWLASAADDHTVKLW 174 Score = 69.3 bits (168), Expect = 8e-12 Identities = 32/100 (32%), Positives = 56/100 (56%) Frame = +1 Query: 133 GQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDI 312 G+ LA+ D V LW+ + + GH + V + + L+++GS+ +++VWD+ Sbjct: 33 GRLLATGGDDCRVNLWSINKPNCIMSLTGHTSPVESVRLNTPEELIVAGSQSGSIRVWDL 92 Query: 313 RARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 A K+ + L GH + ++D+ P GE V SG +D +KLW Sbjct: 93 EAAKILRTLMGHKANICSLDFHPYGEFVASGSQDTNIKLW 132 Score = 52.8 bits (125), Expect = 8e-07 Identities = 31/93 (33%), Positives = 47/93 (50%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 L S +DD T+ LW+ T K + GH VN V F P+ LAS S D++++ W+ Sbjct: 162 LASAADDHTVKLWDLTAGKM-MSEFPGHTGPVNVVEFHPNEYLLASGSSDRTIRFWDLEK 220 Query: 193 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDS 291 + V+ G V + ++ D L SG +DS Sbjct: 221 FQVVSCIEGEPGPVRSVLFNPDGCCLYSGCQDS 253 Score = 37.4 bits (85), Expect = 0.035 Identities = 17/60 (28%), Positives = 29/60 (48%) Frame = +1 Query: 253 ADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 A RLL +G D + +W I L GH V +V + E +V+G + ++++W Sbjct: 31 ASGRLLATGGDDCRVNLWSINKPNCIMSLTGHTSPVESVRLNTPEELIVAGSQSGSIRVW 90
>TAF5L_HUMAN (O75529) TAF5-like RNA polymerase II p300/CBP-associated| factor-associated factor 65 kDa subunit 5L (PCAF-associated factor 65 beta) (PAF65-beta) Length = 589 Score = 90.5 bits (223), Expect = 3e-18 Identities = 47/138 (34%), Positives = 75/138 (54%) Frame = +1 Query: 19 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 198 SGS D T LW + P GH V+ V F P+ +LA+ S DK+V+LW+ G Sbjct: 401 SGSHDRTARLWSFDRT-YPLRIYAGHLADVDCVKFHPNSNYLATGSTDKTVRLWSAQQGN 459 Query: 199 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWS 378 V F GH V +++S + + L S +D LK+WD+ + L ++L GH D + ++ +S Sbjct: 460 SVRLFTGHRGPVLSLAFSPNGKYLASAGEDQRLKLWDLASGTLYKELRGHTDNITSLTFS 519 Query: 379 PDGEKVVSGGKDRALKLW 432 PD + S D ++++W Sbjct: 520 PDSGLIASASMDNSVRVW 537 Score = 77.8 bits (190), Expect = 2e-14 Identities = 42/119 (35%), Positives = 66/119 (55%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 L +GS D T+ LW + TGH+ V + FSP+G++LASA D+ +KLW+ + Sbjct: 441 LATGSTDKTVRLWSAQQGNSVRL-FTGHRGPVLSLAFSPNGKYLASAGEDQRLKLWDLAS 499 Query: 193 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAV 369 G RGH ++ +++S DS L+ S S D++++VWDIR G + E+ V Sbjct: 500 GTLYKELRGHTDNITSLTFSPDSGLIASASMDNSVRVWDIRNTYCSAPADGSSSELVGV 558 Score = 54.3 bits (129), Expect = 3e-07 Identities = 31/116 (26%), Positives = 51/116 (43%) Frame = +1 Query: 85 MTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSR 264 + GH V F D L S S D S++ W+ + ++GH V+ + S S Sbjct: 338 LRGHCGPVYSTRFLADSSGLLSCSEDMSIRYWDLGSFTNTVLYQGHAYPVWDLDISPYSL 397 Query: 265 LLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 SGS D T ++W + GH +V V + P+ + +G D+ ++LW Sbjct: 398 YFASGSHDRTARLWSFDRTYPLRIYAGHLADVDCVKFHPNSNYLATGSTDKTVRLW 453 Score = 53.1 bits (126), Expect = 6e-07 Identities = 40/140 (28%), Positives = 62/140 (44%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 L +G D+ + LW + K + HQ V+ ++ + D + D+ Sbjct: 283 LAAGFDNSCIKLWS---LRSKKLKSEPHQVDVSRIHLACD---ILEEEDDEDDN-----A 331 Query: 193 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVD 372 G + RGH VY + ADS LLS S+D +++ WD+ + GHA V+ +D Sbjct: 332 GTEMKILRGHCGPVYSTRFLADSSGLLSCSEDMSIRYWDLGSFTNTVLYQGHAYPVWDLD 391 Query: 373 WSPDGEKVVSGGKDRALKLW 432 SP SG DR +LW Sbjct: 392 ISPYSLYFASGSHDRTARLW 411 Score = 36.2 bits (82), Expect = 0.077 Identities = 22/93 (23%), Positives = 39/93 (41%), Gaps = 32/93 (34%) Frame = +1 Query: 250 SADSRLLLSGSKDSTLKVWDIRARKLKQD------------------------------- 336 S DS+LL +G +S +K+W +R++KLK + Sbjct: 277 SPDSKLLAAGFDNSCIKLWSLRSKKLKSEPHQVDVSRIHLACDILEEEDDEDDNAGTEMK 336 Query: 337 -LPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 L GH VY+ + D ++S +D +++ W Sbjct: 337 ILRGHCGPVYSTRFLADSSGLLSCSEDMSIRYW 369
>GBLP_BIOGL (Q93134) Guanine nucleotide-binding protein beta subunit 2-like 1| (Receptor of activated protein kinase C) (RACK) Length = 316 Score = 90.5 bits (223), Expect = 3e-18 Identities = 51/150 (34%), Positives = 84/150 (56%), Gaps = 7/150 (4%) Frame = +1 Query: 4 PXRLVSGSDDFTMFLWEPTISKQ----PKARMTGHQKVVNHVYFSPDGQWLASASFDKSV 171 P ++S S D ++ +W T + P+ + GH V+ V S DGQ+ S S+D ++ Sbjct: 28 PDMILSASRDKSLIVWRLTRDESSYGVPQKSLHGHGHFVSDVILSSDGQFALSGSWDHTL 87 Query: 172 KLWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWD-IRARKLKQDLPGH 348 +LW+ TG+ F GH DV +++SAD+R ++SGS+D T+K+W+ + K H Sbjct: 88 RLWDLSTGQTTRRFVGHTKDVLSVAFSADNRQIVSGSRDKTIKLWNTLGVCKYTIQDDCH 147 Query: 349 ADEVYAVDWSPDGEK--VVSGGKDRALKLW 432 D V +SP+ + +VS G DR +K+W Sbjct: 148 TDWTSCVRFSPNTQNPIIVSSGWDRLVKVW 177 Score = 62.8 bits (151), Expect = 8e-10 Identities = 42/127 (33%), Positives = 62/127 (48%), Gaps = 2/127 (1%) Frame = +1 Query: 10 RLVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQ--WLASASFDKSVKLWN 183 ++VSGS D T+ LW + + H + V FSP+ Q + S+ +D+ VK+WN Sbjct: 119 QIVSGSRDKTIKLWNTLGVCKYTIQDDCHTDWTSCVRFSPNTQNPIIVSSGWDRLVKVWN 178 Query: 184 GITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVY 363 K T GH V ++ S D L SG KDS +WD+ K L G D + Sbjct: 179 LTNCKLKTNHYGHTGYVNTVTVSPDGSLCASGGKDSQAMLWDLNEGKHLYTLDGAGDTIN 238 Query: 364 AVDWSPD 384 A+ +SP+ Sbjct: 239 ALCFSPN 245 Score = 57.4 bits (137), Expect = 3e-08 Identities = 41/147 (27%), Positives = 66/147 (44%), Gaps = 7/147 (4%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 +VS D + +W T K K GH VN V SPDG AS D LW+ Sbjct: 165 IVSSGWDRLVKVWNLTNCKL-KTNHYGHTGYVNTVTVSPDGSLCASGGKDSQAMLWDLNE 223 Query: 193 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRAR----KLKQDLPG---HA 351 GK + G D + +R L + ++K+WD+ + +LK ++ G A Sbjct: 224 GKHLYTLDG-AGDTINALCFSPNRYWLCVASGPSIKIWDLEGKVVVDELKPEVMGTTSKA 282 Query: 352 DEVYAVDWSPDGEKVVSGGKDRALKLW 432 ++ WS DG+ + +G D+ +++W Sbjct: 283 PTCLSLAWSADGQTLFAGYTDKLIRVW 309 Score = 45.1 bits (105), Expect = 2e-04 Identities = 30/106 (28%), Positives = 46/106 (43%), Gaps = 8/106 (7%) Frame = +1 Query: 19 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 198 SG D LW+ K + G +N + FSP+ WL AS S+K+W+ + GK Sbjct: 209 SGGKDSQAMLWDLNEGKHLYT-LDGAGDTINALCFSPNRYWLCVAS-GPSIKIWD-LEGK 265 Query: 199 FVT--------AFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDI 312 V ++WSAD + L +G D ++VW + Sbjct: 266 VVVDELKPEVMGTTSKAPTCLSLAWSADGQTLFAGYTDKLIRVWQV 311
>GBLP_ORENI (O42249) Guanine nucleotide-binding protein beta subunit 2-like 1| (Receptor of activated protein kinase C) (RACK) Length = 317 Score = 90.5 bits (223), Expect = 3e-18 Identities = 50/150 (33%), Positives = 85/150 (56%), Gaps = 7/150 (4%) Frame = +1 Query: 4 PXRLVSGSDDFTMFLWEPTISKQ----PKARMTGHQKVVNHVYFSPDGQWLASASFDKSV 171 P ++S S D ++ +W+ T + P+ + GH V+ V S DGQ+ S ++D ++ Sbjct: 28 PDMILSASRDKSIIMWKLTRDETNYGIPQRSLKGHSHFVSDVVISSDGQFALSGAWDGTL 87 Query: 172 KLWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWD-IRARKLKQDLPGH 348 +LW+ TG F GH DV +++SAD+R ++SGS+D T+K+W+ + K GH Sbjct: 88 RLWDLTTGLTTRRFVGHTKDVLSVAFSADNRQIVSGSRDKTIKLWNTLGVCKYTIQDEGH 147 Query: 349 ADEVYAVDWSPDGEK--VVSGGKDRALKLW 432 + V V +SP+ +VS G D+ +K+W Sbjct: 148 TEWVSCVRFSPNSSNPIIVSCGWDKMVKVW 177 Score = 58.9 bits (141), Expect = 1e-08 Identities = 41/127 (32%), Positives = 61/127 (48%), Gaps = 2/127 (1%) Frame = +1 Query: 10 RLVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQ--WLASASFDKSVKLWN 183 ++VSGS D T+ LW + + GH + V+ V FSP+ + S +DK VK+WN Sbjct: 119 QIVSGSRDKTIKLWNTLGVCKYTIQDEGHTEWVSCVRFSPNSSNPIIVSCGWDKMVKVWN 178 Query: 184 GITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVY 363 K T GH + ++ S D L SG KD +WD+ K L D + Sbjct: 179 LANCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDS-GDVIN 237 Query: 364 AVDWSPD 384 A+ +SP+ Sbjct: 238 ALCFSPN 244 Score = 47.0 bits (110), Expect = 4e-05 Identities = 30/108 (27%), Positives = 51/108 (47%), Gaps = 10/108 (9%) Frame = +1 Query: 19 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 198 SG D LW+ K +G V+N + FSP+ WL +A+ S+K+W+ + GK Sbjct: 209 SGGKDGQAMLWDLNEGKHLYTLDSGD--VINALCFSPNRYWLCAAT-GPSIKIWD-LEGK 264 Query: 199 FV----------TAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDI 312 + T + ++WSAD + L +G D+ ++VW + Sbjct: 265 IIVDELRQEVISTNSKAEPPQCTSLAWSADGQTLFAGYTDNLIRVWQV 312
>KTNB1_HUMAN (Q9BVA0) Katanin p80 WD40-containing subunit B1 (Katanin p80| subunit B1) (p80 katanin) Length = 655 Score = 90.5 bits (223), Expect = 3e-18 Identities = 50/134 (37%), Positives = 75/134 (55%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 + SGS D + LW+ K R GH + V + FSPDG+WLASA+ D +VKLW+ Sbjct: 120 VASGSQDTNIKLWDIR-RKGCVFRYRGHSQAVRCLRFSPDGKWLASAADDHTVKLWDLTA 178 Query: 193 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVD 372 GK ++ F GH V + + + LL SGS D T++ WD+ ++ + G V +V Sbjct: 179 GKMMSEFPGHTGPVNVVEFHPNEYLLASGSSDRTIRFWDLEKFQVVSCIEGEPGPVRSVL 238 Query: 373 WSPDGEKVVSGGKD 414 ++PDG + SG +D Sbjct: 239 FNPDGCCLYSGCQD 252 Score = 86.7 bits (213), Expect = 5e-17 Identities = 45/140 (32%), Positives = 78/140 (55%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 +V+GS ++ +W+ +K + M GH+ + + F P G+++AS S D ++KLW+ Sbjct: 78 IVAGSQSGSIRVWDLEAAKILRTLM-GHKANICSLDFHPYGEFVASGSQDTNIKLWDIRR 136 Query: 193 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVD 372 V +RGH V + +S D + L S + D T+K+WD+ A K+ + PGH V V+ Sbjct: 137 KGCVFRYRGHSQAVRCLRFSPDGKWLASAADDHTVKLWDLTAGKMMSEFPGHTGPVNVVE 196 Query: 373 WSPDGEKVVSGGKDRALKLW 432 + P+ + SG DR ++ W Sbjct: 197 FHPNEYLLASGSSDRTIRFW 216 Score = 74.7 bits (182), Expect = 2e-13 Identities = 43/142 (30%), Positives = 72/142 (50%), Gaps = 2/142 (1%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARM--TGHQKVVNHVYFSPDGQWLASASFDKSVKLWNG 186 L +G DD + LW +I+K P M TGH V V + + + + S S+++W+ Sbjct: 36 LATGGDDCRVNLW--SINK-PNCIMSLTGHTSPVESVRLNTPEELIVAGSQSGSIRVWDL 92 Query: 187 ITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYA 366 K + GH A++ + + + SGS+D+ +K+WDIR + GH+ V Sbjct: 93 EAAKILRTLMGHKANICSLDFHPYGEFVASGSQDTNIKLWDIRRKGCVFRYRGHSQAVRC 152 Query: 367 VDWSPDGEKVVSGGKDRALKLW 432 + +SPDG+ + S D +KLW Sbjct: 153 LRFSPDGKWLASAADDHTVKLW 174 Score = 69.3 bits (168), Expect = 8e-12 Identities = 32/100 (32%), Positives = 56/100 (56%) Frame = +1 Query: 133 GQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDI 312 G+ LA+ D V LW+ + + GH + V + + L+++GS+ +++VWD+ Sbjct: 33 GRLLATGGDDCRVNLWSINKPNCIMSLTGHTSPVESVRLNTPEELIVAGSQSGSIRVWDL 92 Query: 313 RARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 A K+ + L GH + ++D+ P GE V SG +D +KLW Sbjct: 93 EAAKILRTLMGHKANICSLDFHPYGEFVASGSQDTNIKLW 132 Score = 52.8 bits (125), Expect = 8e-07 Identities = 31/93 (33%), Positives = 47/93 (50%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 L S +DD T+ LW+ T K + GH VN V F P+ LAS S D++++ W+ Sbjct: 162 LASAADDHTVKLWDLTAGKM-MSEFPGHTGPVNVVEFHPNEYLLASGSSDRTIRFWDLEK 220 Query: 193 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDS 291 + V+ G V + ++ D L SG +DS Sbjct: 221 FQVVSCIEGEPGPVRSVLFNPDGCCLYSGCQDS 253 Score = 37.4 bits (85), Expect = 0.035 Identities = 17/60 (28%), Positives = 29/60 (48%) Frame = +1 Query: 253 ADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 A RLL +G D + +W I L GH V +V + E +V+G + ++++W Sbjct: 31 ASGRLLATGGDDCRVNLWSINKPNCIMSLTGHTSPVESVRLNTPEELIVAGSQSGSIRVW 90
>GBLP_SOYBN (Q39836) Guanine nucleotide-binding protein beta subunit-like| protein Length = 325 Score = 89.4 bits (220), Expect = 8e-18 Identities = 51/148 (34%), Positives = 79/148 (53%), Gaps = 8/148 (5%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQ----PKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLW 180 +V+ S D ++ LW T + P+ R+TGH V V S DGQ+ S S+D ++LW Sbjct: 31 IVTASRDRSIILWHLTKEDKTYGVPRRRLTGHSHFVQDVVLSSDGQFALSGSWDGELRLW 90 Query: 181 NGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDI--RARKLKQDLPGHAD 354 + G F GH DV +++S D+R ++S S+D T+K+W+ + QD H+D Sbjct: 91 DLAAGTSARRFVGHTKDVLSVAFSIDNRQIVSASRDRTIKLWNTLGECKYTIQDGDAHSD 150 Query: 355 EVYAVDWSPD--GEKVVSGGKDRALKLW 432 V V +SP +VS DR +K+W Sbjct: 151 WVSCVRFSPSTLQPTIVSASWDRTVKVW 178 Score = 59.7 bits (143), Expect = 7e-09 Identities = 43/158 (27%), Positives = 74/158 (46%), Gaps = 18/158 (11%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 +VS S D T+ +W T K + + GH VN V SPDG AS D + LW+ Sbjct: 166 IVSASWDRTVKVWNLTNCKL-RNTLAGHNGYVNTVAVSPDGSLCASGGKDGVILLWDLAE 224 Query: 193 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLP---------- 342 GK + + + + SR L + + ++K+WD+ ++ + +DL Sbjct: 225 GKRLYSL--DAGSIIHALCFSPSRYWLCAATEQSIKIWDLESKSIVEDLKVDLKTEADAT 282 Query: 343 ---GHADE---VY--AVDWSPDGEKVVSGGKDRALKLW 432 G+A++ +Y +++WS DG + SG D ++W Sbjct: 283 SGGGNANKKKVIYCTSLNWSADGSTLFSGYTDGVARVW 320 Score = 56.2 bits (134), Expect = 7e-08 Identities = 43/145 (29%), Positives = 69/145 (47%), Gaps = 4/145 (2%) Frame = +1 Query: 10 RLVSGSDDFTMFLWEPTISKQPKARMTG--HQKVVNHVYFSPDG--QWLASASFDKSVKL 177 ++VS S D T+ LW T+ + G H V+ V FSP + SAS+D++VK+ Sbjct: 119 QIVSASRDRTIKLWN-TLGECKYTIQDGDAHSDWVSCVRFSPSTLQPTIVSASWDRTVKV 177 Query: 178 WNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADE 357 WN K GH V ++ S D L SG KD + +WD+ K L Sbjct: 178 WNLTNCKLRNTLAGHNGYVNTVAVSPDGSLCASGGKDGVILLWDLAEGKRLYSLDA-GSI 236 Query: 358 VYAVDWSPDGEKVVSGGKDRALKLW 432 ++A+ +SP + ++++K+W Sbjct: 237 IHALCFSP-SRYWLCAATEQSIKIW 260 Score = 41.2 bits (95), Expect = 0.002 Identities = 30/116 (25%), Positives = 50/116 (43%), Gaps = 18/116 (15%) Frame = +1 Query: 19 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 198 SG D + LW+ K+ + G +++ + FSP WL +A+ ++S+K+W+ + Sbjct: 210 SGGKDGVILLWDLAEGKRLYSLDAG--SIIHALCFSPSRYWLCAAT-EQSIKIWDLESKS 266 Query: 199 FV------------------TAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDI 312 V A + V ++WSAD L SG D +VW I Sbjct: 267 IVEDLKVDLKTEADATSGGGNANKKKVIYCTSLNWSADGSTLFSGYTDGVARVWAI 322
>GBLP_MEDSA (O24076) Guanine nucleotide-binding protein beta subunit-like| protein Length = 325 Score = 89.4 bits (220), Expect = 8e-18 Identities = 51/148 (34%), Positives = 80/148 (54%), Gaps = 8/148 (5%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQ----PKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLW 180 +V+ S D ++ LW T + P+ R+TGH V V S DGQ+ S S+D ++LW Sbjct: 31 IVTASRDKSIILWHLTKEDKTYGVPRRRLTGHSHFVQDVVLSSDGQFALSGSWDGELRLW 90 Query: 181 NGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDI--RARKLKQDLPGHAD 354 + G F GH DV +++S D+R ++S S+D T+K+W+ + QD H+D Sbjct: 91 DLNAGTSARRFVGHTKDVLSVAFSIDNRQIVSASRDRTIKLWNTLGECKYTIQDGDAHSD 150 Query: 355 EVYAVDWSPDGEK--VVSGGKDRALKLW 432 V V +SP + +VS DR +K+W Sbjct: 151 WVSCVRFSPSTPQPTIVSASWDRTVKVW 178 Score = 60.5 bits (145), Expect = 4e-09 Identities = 44/158 (27%), Positives = 71/158 (44%), Gaps = 18/158 (11%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 +VS S D T+ +W T K + + GH VN V SPDG AS D + LW+ Sbjct: 166 IVSASWDRTVKVWNLTNCKL-RNTLAGHSGYVNTVAVSPDGSLCASGGKDGVILLWDLAE 224 Query: 193 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARK----LKQDLPGHADEV 360 GK + + + + +R L + +S++K+WD+ ++ LK DL AD Sbjct: 225 GKRLYSL--DAGSIIHALCFSPNRYWLCAATESSIKIWDLESKSIVEDLKVDLKTEADAA 282 Query: 361 Y--------------AVDWSPDGEKVVSGGKDRALKLW 432 +++WS DG + SG D +++W Sbjct: 283 IGGDTTTKKKVIYCTSLNWSADGSTLFSGYTDGVVRVW 320 Score = 56.2 bits (134), Expect = 7e-08 Identities = 43/145 (29%), Positives = 69/145 (47%), Gaps = 4/145 (2%) Frame = +1 Query: 10 RLVSGSDDFTMFLWEPTISKQPKARMTG--HQKVVNHVYFSPDGQW--LASASFDKSVKL 177 ++VS S D T+ LW T+ + G H V+ V FSP + SAS+D++VK+ Sbjct: 119 QIVSASRDRTIKLWN-TLGECKYTIQDGDAHSDWVSCVRFSPSTPQPTIVSASWDRTVKV 177 Query: 178 WNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADE 357 WN K GH V ++ S D L SG KD + +WD+ K L Sbjct: 178 WNLTNCKLRNTLAGHSGYVNTVAVSPDGSLCASGGKDGVILLWDLAEGKRLYSLDA-GSI 236 Query: 358 VYAVDWSPDGEKVVSGGKDRALKLW 432 ++A+ +SP+ + + ++K+W Sbjct: 237 IHALCFSPN-RYWLCAATESSIKIW 260 Score = 43.1 bits (100), Expect = 6e-04 Identities = 30/116 (25%), Positives = 51/116 (43%), Gaps = 18/116 (15%) Frame = +1 Query: 19 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 198 SG D + LW+ K+ + G +++ + FSP+ WL +A+ + S+K+W+ + Sbjct: 210 SGGKDGVILLWDLAEGKRLYSLDAG--SIIHALCFSPNRYWLCAAT-ESSIKIWDLESKS 266 Query: 199 FV------------------TAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDI 312 V T + V ++WSAD L SG D ++VW I Sbjct: 267 IVEDLKVDLKTEADAAIGGDTTTKKKVIYCTSLNWSADGSTLFSGYTDGVVRVWGI 322
>YKY4_CAEEL (Q17963) Hypothetical WD-repeat protein C14B1.4| Length = 376 Score = 89.4 bits (220), Expect = 8e-18 Identities = 42/116 (36%), Positives = 70/116 (60%) Frame = +1 Query: 85 MTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSR 264 + GH K ++ FSP G++L ++S DK+VK+WN GH V I+WS+DSR Sbjct: 83 LEGHTKSISSAKFSPCGKYLGTSSADKTVKIWNMDHMICERTLTGHKLGVNDIAWSSDSR 142 Query: 265 LLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 ++S S D TLK+++I ++ + L GH + V+ +++P VVSG D ++++W Sbjct: 143 CVVSASDDKTLKIFEIVTSRMTKTLKGHNNYVFCCNFNPQSSLVVSGSFDESVRIW 198 Score = 84.7 bits (208), Expect = 2e-16 Identities = 38/116 (32%), Positives = 71/116 (61%) Frame = +1 Query: 85 MTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSR 264 +TGH+ VN + +S D + + SAS DK++K++ +T + +GH V+ +++ S Sbjct: 125 LTGHKLGVNDIAWSSDSRCVVSASDDKTLKIFEIVTSRMTKTLKGHNNYVFCCNFNPQSS 184 Query: 265 LLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 L++SGS D ++++WD++ + LP H+D V AV ++ DG + SG D +++W Sbjct: 185 LVVSGSFDESVRIWDVKTGMCIKTLPAHSDPVSAVSFNRDGSLIASGSYDGLVRIW 240 Score = 79.3 bits (194), Expect = 8e-15 Identities = 45/141 (31%), Positives = 74/141 (52%), Gaps = 1/141 (0%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 +VS SDD T+ ++E S+ K + GH V F+P + S SFD+SV++W+ T Sbjct: 144 VVSASDDKTLKIFEIVTSRMTKT-LKGHNNYVFCCNFNPQSSLVVSGSFDESVRIWDVKT 202 Query: 193 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWD-IRARKLKQDLPGHADEVYAV 369 G + H V +S++ D L+ SGS D +++WD + +K + V V Sbjct: 203 GMCIKTLPAHSDPVSAVSFNRDGSLIASGSYDGLVRIWDTANGQCIKTLVDDENPPVAFV 262 Query: 370 DWSPDGEKVVSGGKDRALKLW 432 +SP+G+ +++ D LKLW Sbjct: 263 KFSPNGKYILASNLDSTLKLW 283 Score = 70.9 bits (172), Expect = 3e-12 Identities = 40/145 (27%), Positives = 73/145 (50%), Gaps = 5/145 (3%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 + SGS D + +W+ + K + V V FSP+G+++ +++ D ++KLW+ Sbjct: 228 IASGSYDGLVRIWDTANGQCIKTLVDDENPPVAFVKFSPNGKYILASNLDSTLKLWDFSK 287 Query: 193 GKFVTAFRGHVADVYQISWS---ADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVY 363 GK + + GH Y I + + ++SGS+D + +W+++ R++ Q L GH V Sbjct: 288 GKTLKQYTGHENSKYCIFANFSVTGGKWIISGSEDCKIYIWNLQTREIVQCLEGHTQPVL 347 Query: 364 AVDWSPDGEKVVSGG--KDRALKLW 432 A D P + SG D + +W Sbjct: 348 ASDCHPVQNIIASGALEPDNKIHIW 372 Score = 46.2 bits (108), Expect = 7e-05 Identities = 23/79 (29%), Positives = 38/79 (48%) Frame = +1 Query: 196 KFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDW 375 K + GH + +S + L + S D T+K+W++ ++ L GH V + W Sbjct: 78 KLMCTLEGHTKSISSAKFSPCGKYLGTSSADKTVKIWNMDHMICERTLTGHKLGVNDIAW 137 Query: 376 SPDGEKVVSGGKDRALKLW 432 S D VVS D+ LK++ Sbjct: 138 SSDSRCVVSASDDKTLKIF 156
>UTP13_SCHPO (Q9USN3) Probable U3 small nucleolar RNA-associated protein 13 (U3| snoRNA-associated protein 13) Length = 777 Score = 89.0 bits (219), Expect = 1e-17 Identities = 51/150 (34%), Positives = 79/150 (52%), Gaps = 7/150 (4%) Frame = +1 Query: 4 PXRLVSGSDDFTMF-------LWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFD 162 P L S S D T+ L + S + + H + VN + S DG+ +ASAS D Sbjct: 427 PTFLASSSQDRTLKRFNLGSQLNKSDFSNRAVWTIKAHDRDVNAIQVSKDGRIIASASQD 486 Query: 163 KSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLP 342 K++KLW+ TG+ V RGH V+ S++ SR L SGS D T+++W++ ++ Q L Sbjct: 487 KTIKLWDSSTGEVVGVLRGHRRGVWACSFNPFSRQLASGSGDRTIRIWNVDTQQCVQTLE 546 Query: 343 GHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 GH + + + G +VVS D +K+W Sbjct: 547 GHTGAILKLIYISQGTQVVSAAADGLVKVW 576 Score = 60.8 bits (146), Expect = 3e-09 Identities = 40/133 (30%), Positives = 64/133 (48%), Gaps = 17/133 (12%) Frame = +1 Query: 85 MTGHQKVVNHVYFSPDGQWLASASFDKSVKLWN----GITGKFVTAFRGHVADVYQISW- 249 + GH +V + S DG WLA+ + D +V+LWN K + F GH A V ++ Sbjct: 360 LEGHTDIVLTLDSSEDGVWLATGAKDNTVRLWNLNIEDNVYKCIHVFTGHTASVTAVALG 419 Query: 250 ----SADSRLLLSGSKDSTLKVWDIRARKLKQD--------LPGHADEVYAVDWSPDGEK 393 + L S S+D TLK +++ ++ K D + H +V A+ S DG Sbjct: 420 PLDVNGYPTFLASSSQDRTLKRFNLGSQLNKSDFSNRAVWTIKAHDRDVNAIQVSKDGRI 479 Query: 394 VVSGGKDRALKLW 432 + S +D+ +KLW Sbjct: 480 IASASQDKTIKLW 492 Score = 60.5 bits (145), Expect = 4e-09 Identities = 36/132 (27%), Positives = 69/132 (52%), Gaps = 7/132 (5%) Frame = +1 Query: 58 TISKQPKAR----MTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVT-AFRGH 222 TI + P R M H+ V + P LA+ + VK+W+ I G +VT +FRGH Sbjct: 86 TIYEIPSGRRIKSMKAHETPVITMTIDPTNTLLATGGAEGLVKVWD-IAGAYVTHSFRGH 144 Query: 223 VADVYQISWS--ADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKV 396 + + + ++ +L SG+ DS +++WD+ + + GH+ + + + P G + Sbjct: 145 GGVISALCFGKHQNTWVLASGADDSRVRLWDLNSSRSMAVFEGHSSVIRGLTFEPTGSFL 204 Query: 397 VSGGKDRALKLW 432 +SG +D+ +++W Sbjct: 205 LSGSRDKTVQVW 216 Score = 55.5 bits (132), Expect = 1e-07 Identities = 33/119 (27%), Positives = 61/119 (51%), Gaps = 5/119 (4%) Frame = +1 Query: 91 GHQKVVNHVYFSP-DGQW-LASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSR 264 GH V++ + F W LAS + D V+LW+ + + + F GH + + +++ Sbjct: 143 GHGGVISALCFGKHQNTWVLASGADDSRVRLWDLNSSRSMAVFEGHSSVIRGLTFEPTGS 202 Query: 265 LLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDW---SPDGEKVVSGGKDRALKLW 432 LLSGS+D T++VW+I+ R + +P V A+ W P+ + + + G+ + W Sbjct: 203 FLLSGSRDKTVQVWNIKKRSAVRTIPVF-HSVEAIGWVNGQPEEKILYTAGEGNLILAW 260 Score = 47.0 bits (110), Expect = 4e-05 Identities = 30/102 (29%), Positives = 48/102 (47%), Gaps = 3/102 (2%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 L SG+DD + LW+ S+ A GH V+ + F P G +L S S DK+V++WN I Sbjct: 162 LASGADDSRVRLWDLNSSRS-MAVFEGHSSVIRGLTFEPTGSFLLSGSRDKTVQVWN-IK 219 Query: 193 GKFVTAFRGHVADVYQISW---SADSRLLLSGSKDSTLKVWD 309 + V I W + ++L + + + + WD Sbjct: 220 KRSAVRTIPVFHSVEAIGWVNGQPEEKILYTAGEGNLILAWD 261 Score = 38.5 bits (88), Expect = 0.016 Identities = 23/111 (20%), Positives = 49/111 (44%), Gaps = 2/111 (1%) Frame = +1 Query: 106 VNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSK 285 V + + D + L +A + + ++ +G+ + + + H V ++ + LL +G Sbjct: 64 VTALAITSDSKKLIAAFRSRLLTIYEIPSGRRIKSMKAHETPVITMTIDPTNTLLATGGA 123 Query: 286 DSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEK--VVSGGKDRALKLW 432 + +KVWDI + GH + A+ + + SG D ++LW Sbjct: 124 EGLVKVWDIAGAYVTHSFRGHGGVISALCFGKHQNTWVLASGADDSRVRLW 174
>GBLP_NICPL (P93340) Guanine nucleotide-binding protein beta subunit-like| protein Length = 326 Score = 88.2 bits (217), Expect = 2e-17 Identities = 49/148 (33%), Positives = 81/148 (54%), Gaps = 8/148 (5%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQ----PKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLW 180 +V+ S D ++ +W T P+ R+TGH V V S DG + S S+D ++LW Sbjct: 32 IVTSSRDKSIIVWSLTKDGPQYGVPRRRLTGHGHFVQDVVLSSDGMFALSGSWDGELRLW 91 Query: 181 NGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDI--RARKLKQDLPGHAD 354 + G F GH DV +++SAD+R ++S S+D ++++W+ + + QD H+D Sbjct: 92 DLQAGTTARRFVGHTKDVLSVAFSADNRQIVSASRDKSIRLWNTLGECKYIIQDGDSHSD 151 Query: 355 EVYAVDWSPDG--EKVVSGGKDRALKLW 432 V V +SP+ +VSG DR +K+W Sbjct: 152 WVSCVRFSPNNLQPTIVSGSWDRTVKIW 179 Score = 61.6 bits (148), Expect = 2e-09 Identities = 44/158 (27%), Positives = 75/158 (47%), Gaps = 18/158 (11%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 +VSGS D T+ +W T K +A + GH VN SPDG AS D + LW+ Sbjct: 167 IVSGSWDRTVKIWNLTNCKL-RATLAGHTGYVNTTAVSPDGSLCASGGKDGVILLWDLAE 225 Query: 193 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLP---------- 342 GK + + + ++ + +S + R L + +S++K+WD+ ++ + DL Sbjct: 226 GKKLYSLESG-SIIHSLCFSPN-RYWLCAATESSIKIWDLESKTIVDDLKVDLKQESEMS 283 Query: 343 ------GHADEVY--AVDWSPDGEKVVSGGKDRALKLW 432 G +Y ++ WS DG + SG D +++W Sbjct: 284 AEGTASGKNKVIYCTSLGWSADGSTLFSGYTDGLIRVW 321 Score = 52.4 bits (124), Expect = 1e-06 Identities = 40/145 (27%), Positives = 68/145 (46%), Gaps = 4/145 (2%) Frame = +1 Query: 10 RLVSGSDDFTMFLWEPTISKQPKARMTG--HQKVVNHVYFSPDG--QWLASASFDKSVKL 177 ++VS S D ++ LW T+ + G H V+ V FSP+ + S S+D++VK+ Sbjct: 120 QIVSASRDKSIRLWN-TLGECKYIIQDGDSHSDWVSCVRFSPNNLQPTIVSGSWDRTVKI 178 Query: 178 WNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADE 357 WN K GH V + S D L SG KD + +WD+ K L Sbjct: 179 WNLTNCKLRATLAGHTGYVNTTAVSPDGSLCASGGKDGVILLWDLAEGKKLYSLES-GSI 237 Query: 358 VYAVDWSPDGEKVVSGGKDRALKLW 432 ++++ +SP+ + + ++K+W Sbjct: 238 IHSLCFSPN-RYWLCAATESSIKIW 261 Score = 43.5 bits (101), Expect = 5e-04 Identities = 28/116 (24%), Positives = 52/116 (44%), Gaps = 18/116 (15%) Frame = +1 Query: 19 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWN----- 183 SG D + LW+ K+ + +G +++ + FSP+ WL +A+ + S+K+W+ Sbjct: 211 SGGKDGVILLWDLAEGKKLYSLESG--SIIHSLCFSPNRYWLCAAT-ESSIKIWDLESKT 267 Query: 184 -------------GITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDI 312 ++ + + + V + WSAD L SG D ++VW I Sbjct: 268 IVDDLKVDLKQESEMSAEGTASGKNKVIYCTSLGWSADGSTLFSGYTDGLIRVWGI 323
>PRP46_YARLI (Q6C709) Pre-mRNA-splicing factor PRP46 (Pre-mRNA-processing| protein 46) Length = 472 Score = 87.4 bits (215), Expect = 3e-17 Identities = 40/116 (34%), Positives = 62/116 (53%) Frame = +1 Query: 85 MTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSR 264 +TGHQ V V P+ QW A+ S DK++K+W+ TGK GH+ V + S Sbjct: 159 ITGHQGWVRSVCVEPENQWFATGSADKTIKIWDLATGKLRLTLTGHIMGVRALGVSPRHP 218 Query: 265 LLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 + SG +D +K WD+ K+ + GH VY++D P + +VS G+D ++W Sbjct: 219 YMFSGGEDKMVKCWDLETNKVVRHYHGHLSAVYSLDIHPTLDVLVSAGRDAVARVW 274 Score = 75.1 bits (183), Expect = 2e-13 Identities = 42/138 (30%), Positives = 68/138 (49%) Frame = +1 Query: 19 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 198 +GS D T+ +W+ K + +TGH V + SP ++ S DK VK W+ T K Sbjct: 180 TGSADKTIKIWDLATGKL-RLTLTGHIMGVRALGVSPRHPYMFSGGEDKMVKCWDLETNK 238 Query: 199 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWS 378 V + GH++ VY + +L+S +D+ +VWDIR R L GH + V + Sbjct: 239 VVRHYHGHLSAVYSLDIHPTLDVLVSAGRDAVARVWDIRTRDPVVVLSGHKSTINRVKFQ 298 Query: 379 PDGEKVVSGGKDRALKLW 432 +V++ D ++LW Sbjct: 299 ASEPQVITASADETVRLW 316 Score = 48.5 bits (114), Expect = 2e-05 Identities = 33/140 (23%), Positives = 60/140 (42%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 + SG +D + W+ +K + GH V + P L SA D ++W+ T Sbjct: 220 MFSGGEDKMVKCWDLETNKVVR-HYHGHLSAVYSLDIHPTLDVLVSAGRDAVARVWDIRT 278 Query: 193 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVD 372 V GH + + ++ + A +++ S D T+++W+++A K L H V + Sbjct: 279 RDPVVVLSGHKSTINRVKFQASEPQVITASADETVRLWNLQAGKTMTTLTHHKKSVRGLT 338 Query: 373 WSPDGEKVVSGGKDRALKLW 432 P+ E S + K W Sbjct: 339 LHPE-EFTFSTASANSSKQW 357
>GBLP_YEAST (P38011) Guanine nucleotide-binding protein beta subunit-like| protein (Receptor of activated protein kinase C 1) (RACK1) (Receptor for activated C kinase) Length = 318 Score = 87.4 bits (215), Expect = 3e-17 Identities = 52/153 (33%), Positives = 78/153 (50%), Gaps = 10/153 (6%) Frame = +1 Query: 4 PXRLVSGSDDFTMFLWEPTISKQ----PKARMTGHQKVVNHVYFSPDGQWLASASFDKSV 171 P L+S S D T+ W+ T Q P GH +V + DG + SAS+DK++ Sbjct: 29 PNLLLSASRDKTLISWKLTGDDQKFGVPVRSFKGHSHIVQDCTLTADGAYALSASWDKTL 88 Query: 172 KLWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHA 351 +LW+ TG+ F GH +DV + + +++SGS+D T+KVW I+ + L L GH Sbjct: 89 RLWDVATGETYQRFVGHKSDVMSVDIDKKASMIISGSRDKTIKVWTIKGQCL-ATLLGHN 147 Query: 352 DEVYAVDWSP------DGEKVVSGGKDRALKLW 432 D V V P D ++S G D+ +K W Sbjct: 148 DWVSQVRVVPNEKADDDSVTIISAGNDKMVKAW 180 Score = 52.4 bits (124), Expect = 1e-06 Identities = 40/148 (27%), Positives = 70/148 (47%), Gaps = 8/148 (5%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 ++S +D + W Q +A GH +N + SPDG +ASA D + LWN Sbjct: 168 IISAGNDKMVKAWNLN-QFQIEADFIGHNSNINTLTASPDGTLIASAGKDGEIMLWNLAA 226 Query: 193 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLP------GHAD 354 K + +V+ +++S +R L+ + + +KV+ + + L DL A Sbjct: 227 KKAMYTLSAQ-DEVFSLAFS-PNRYWLAAATATGIKVFSLDPQYLVDDLRPEFAGYSKAA 284 Query: 355 EVYAVD--WSPDGEKVVSGGKDRALKLW 432 E +AV WS DG+ + +G D +++W Sbjct: 285 EPHAVSLAWSADGQTLFAGYTDNVIRVW 312 Score = 36.6 bits (83), Expect = 0.059 Identities = 26/108 (24%), Positives = 49/108 (45%), Gaps = 8/108 (7%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASA--------SFDKS 168 + S D + LW +K+ ++ +V + + FSP+ WLA+A S D Sbjct: 210 IASAGKDGEIMLWN-LAAKKAMYTLSAQDEVFS-LAFSPNRYWLAAATATGIKVFSLDPQ 267 Query: 169 VKLWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDI 312 L + + +F + ++WSAD + L +G D+ ++VW + Sbjct: 268 Y-LVDDLRPEFAGYSKAAEPHAVSLAWSADGQTLFAGYTDNVIRVWQV 314
>KTNB1_STRPU (O61585) Katanin p80 WD40-containing subunit B1 (Katanin p80| subunit B1) (p80 katanin) Length = 690 Score = 86.7 bits (213), Expect = 5e-17 Identities = 44/140 (31%), Positives = 80/140 (57%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 +V+GS TM +++ +K + +TGH+ + + F P G+++AS S D +VKLW+ Sbjct: 74 VVAGSQSGTMKIYDLEPAKIVRT-LTGHRNSIRCMDFHPFGEFVASGSTDTNVKLWDVRR 132 Query: 193 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVD 372 + ++GH V I +S D + L++ S+D+T+K+WD+ KL Q+ H V ++ Sbjct: 133 KGCIYTYKGHSDQVNMIKFSPDGKWLVTASEDTTIKLWDLTMGKLFQEFKNHTGGVTGIE 192 Query: 373 WSPDGEKVVSGGKDRALKLW 432 + P+ + SG DR ++ W Sbjct: 193 FHPNEFLLASGSSDRTVQFW 212 Score = 83.6 bits (205), Expect = 4e-16 Identities = 46/134 (34%), Positives = 67/134 (50%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 + SGS D + LW+ K GH VN + FSPDG+WL +AS D ++KLW+ Sbjct: 116 VASGSTDTNVKLWDVR-RKGCIYTYKGHSDQVNMIKFSPDGKWLVTASEDTTIKLWDLTM 174 Query: 193 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVD 372 GK F+ H V I + + LL SGS D T++ WD+ +L A V ++ Sbjct: 175 GKLFQEFKNHTGGVTGIEFHPNEFLLASGSSDRTVQFWDLETFQLVSSTSPGASAVRSIS 234 Query: 373 WSPDGEKVVSGGKD 414 + PDG + +D Sbjct: 235 FHPDGSYLFCSSQD 248 Score = 72.4 bits (176), Expect = 1e-12 Identities = 39/141 (27%), Positives = 74/141 (52%), Gaps = 1/141 (0%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKA-RMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGI 189 +V+G +D + LW + KQ ++GH V+ V F+ + + + S ++K+++ Sbjct: 32 MVTGGEDKKVNLW--AVGKQNCIISLSGHTSPVDSVKFNSSEELVVAGSQSGTMKIYDLE 89 Query: 190 TGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAV 369 K V GH + + + + SGS D+ +K+WD+R + GH+D+V + Sbjct: 90 PAKIVRTLTGHRNSIRCMDFHPFGEFVASGSTDTNVKLWDVRRKGCIYTYKGHSDQVNMI 149 Query: 370 DWSPDGEKVVSGGKDRALKLW 432 +SPDG+ +V+ +D +KLW Sbjct: 150 KFSPDGKWLVTASEDTTIKLW 170 Score = 70.5 bits (171), Expect = 4e-12 Identities = 34/117 (29%), Positives = 61/117 (52%), Gaps = 1/117 (0%) Frame = +1 Query: 85 MTGHQKVVNHVYFSP-DGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADS 261 + H VN + P G+ + + DK V LW + + GH + V + +++ Sbjct: 12 LVAHSSNVNCLALGPMSGRVMVTGGEDKKVNLWAVGKQNCIISLSGHTSPVDSVKFNSSE 71 Query: 262 RLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 L+++GS+ T+K++D+ K+ + L GH + + +D+ P GE V SG D +KLW Sbjct: 72 ELVVAGSQSGTMKIYDLEPAKIVRTLTGHRNSIRCMDFHPFGEFVASGSTDTNVKLW 128
>GBLP_ARATH (O24456) Guanine nucleotide-binding protein beta subunit-like| protein (WD-40 repeat auxin-dependent protein ARCA) Length = 327 Score = 85.9 bits (211), Expect = 9e-17 Identities = 51/151 (33%), Positives = 81/151 (53%), Gaps = 11/151 (7%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKA------RMTGHQKVVNHVYFSPDGQWLASASFDKSVK 174 +VS S D ++ LW+ ++K KA R+TGH V V S DGQ+ S S+D ++ Sbjct: 31 IVSASRDKSIILWK--LTKDDKAYGVAQRRLTGHSHFVEDVVLSSDGQFALSGSWDGELR 88 Query: 175 LWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRAR---KLKQDLPG 345 LW+ G F GH DV +++S D+R ++S S+D T+K+W+ + + G Sbjct: 89 LWDLAAGVSTRRFVGHTKDVLSVAFSLDNRQIVSASRDRTIKLWNTLGECKYTISEGGEG 148 Query: 346 HADEVYAVDWSPD--GEKVVSGGKDRALKLW 432 H D V V +SP+ +VS D+ +K+W Sbjct: 149 HRDWVSCVRFSPNTLQPTIVSASWDKTVKVW 179 Score = 61.6 bits (148), Expect = 2e-09 Identities = 46/149 (30%), Positives = 75/149 (50%), Gaps = 8/149 (5%) Frame = +1 Query: 10 RLVSGSDDFTMFLWEP------TISKQPKARMTGHQKVVNHVYFSPDG--QWLASASFDK 165 ++VS S D T+ LW TIS+ + GH+ V+ V FSP+ + SAS+DK Sbjct: 119 QIVSASRDRTIKLWNTLGECKYTISEGGE----GHRDWVSCVRFSPNTLQPTIVSASWDK 174 Query: 166 SVKLWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPG 345 +VK+WN K + GH V ++ S D L SG KD + +WD+ K L Sbjct: 175 TVKVWNLSNCKLRSTLAGHTGYVSTVAVSPDGSLCASGGKDGVVLLWDLAEGKKLYSLEA 234 Query: 346 HADEVYAVDWSPDGEKVVSGGKDRALKLW 432 ++ ++A+ +SP+ + + +K+W Sbjct: 235 NS-VIHALCFSPN-RYWLCAATEHGIKIW 261 Score = 56.2 bits (134), Expect = 7e-08 Identities = 43/159 (27%), Positives = 77/159 (48%), Gaps = 19/159 (11%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 +VS S D T+ +W + K ++ + GH V+ V SPDG AS D V LW+ Sbjct: 167 IVSASWDKTVKVWNLSNCKL-RSTLAGHTGYVSTVAVSPDGSLCASGGKDGVVLLWDLAE 225 Query: 193 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARK----LKQDLPGHADE- 357 GK + + + ++ + +S + R L + + +K+WD+ ++ LK DL A++ Sbjct: 226 GKKLYSLEANSV-IHALCFSPN-RYWLCAATEHGIKIWDLESKSIVEDLKVDLKAEAEKA 283 Query: 358 ------------VY--AVDWSPDGEKVVSGGKDRALKLW 432 +Y +++WS DG + SG D +++W Sbjct: 284 DNSGPAATKRKVIYCTSLNWSADGSTLFSGYTDGVIRVW 322 Score = 41.2 bits (95), Expect = 0.002 Identities = 29/117 (24%), Positives = 50/117 (42%), Gaps = 19/117 (16%) Frame = +1 Query: 19 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 198 SG D + LW+ +++ K V++ + FSP+ WL +A+ + +K+W+ + Sbjct: 211 SGGKDGVVLLWD--LAEGKKLYSLEANSVIHALCFSPNRYWLCAAT-EHGIKIWDLESKS 267 Query: 199 FV-------------------TAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDI 312 V A + V ++WSAD L SG D ++VW I Sbjct: 268 IVEDLKVDLKAEAEKADNSGPAATKRKVIYCTSLNWSADGSTLFSGYTDGVIRVWGI 324
>TAF5_YEAST (P38129) Transcription initiation factor TFIID subunit 5| (TBP-associated factor 5) (TBP-associated factor 90 kDa) (TAFII-90) Length = 798 Score = 85.5 bits (210), Expect = 1e-16 Identities = 47/139 (33%), Positives = 74/139 (53%), Gaps = 1/139 (0%) Frame = +1 Query: 19 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 198 + S D T LW P GH V+ V F P+G ++ + S DK+ ++W+ TG Sbjct: 584 TASHDQTARLWSCD-HIYPLRIFAGHLNDVDCVSFHPNGCYVFTGSSDKTCRMWDVSTGD 642 Query: 199 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHA-DEVYAVDW 375 V F GH A V I+ D R L +GS+D + VWDI K + + GH + +Y++ + Sbjct: 643 SVRLFLGHTAPVISIAVCPDGRWLSTGSEDGIINVWDIGTGKRLKQMRGHGKNAIYSLSY 702 Query: 376 SPDGEKVVSGGKDRALKLW 432 S +G ++SGG D +++W Sbjct: 703 SKEGNVLISGGADHTVRVW 721 Score = 70.9 bits (172), Expect = 3e-12 Identities = 35/116 (30%), Positives = 60/116 (51%) Frame = +1 Query: 85 MTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSR 264 + GH V FSPD ++L S S DK+V+LW+ T + +++GH V+ +S+S Sbjct: 521 LVGHSGTVYSTSFSPDNKYLLSGSEDKTVRLWSMDTHTALVSYKGHNHPVWDVSFSPLGH 580 Query: 265 LLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 + S D T ++W + GH ++V V + P+G V +G D+ ++W Sbjct: 581 YFATASHDQTARLWSCDHIYPLRIFAGHLNDVDCVSFHPNGCYVFTGSSDKTCRMW 636 Score = 67.8 bits (164), Expect = 2e-11 Identities = 35/101 (34%), Positives = 59/101 (58%), Gaps = 2/101 (1%) Frame = +1 Query: 19 SGSDDFTMFLWEPTISKQPKARM-TGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITG 195 +GS D T +W+ +S R+ GH V + PDG+WL++ S D + +W+ TG Sbjct: 626 TGSSDKTCRMWD--VSTGDSVRLFLGHTAPVISIAVCPDGRWLSTGSEDGIINVWDIGTG 683 Query: 196 KFVTAFRGHVAD-VYQISWSADSRLLLSGSKDSTLKVWDIR 315 K + RGH + +Y +S+S + +L+SG D T++VWD++ Sbjct: 684 KRLKQMRGHGKNAIYSLSYSKEGNVLISGGADHTVRVWDLK 724 Score = 31.2 bits (69), Expect = 2.5 Identities = 18/58 (31%), Positives = 33/58 (56%), Gaps = 1/58 (1%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQK-VVNHVYFSPDGQWLASASFDKSVKLWN 183 L +GS+D + +W+ K+ K +M GH K + + +S +G L S D +V++W+ Sbjct: 666 LSTGSEDGIINVWDIGTGKRLK-QMRGHGKNAIYSLSYSKEGNVLISGGADHTVRVWD 722
>GBLP_CHLRE (P25387) Guanine nucleotide-binding protein beta subunit-like| protein Length = 318 Score = 85.5 bits (210), Expect = 1e-16 Identities = 49/148 (33%), Positives = 81/148 (54%), Gaps = 8/148 (5%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQ----PKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLW 180 L+S S D ++ +WE S+ + + GH V V S DGQ+ + S+D +++LW Sbjct: 32 LLSASRDKSVLVWELERSESNYGYARKALRGHSHFVQDVVISSDGQFCLTGSWDGTLRLW 91 Query: 181 NGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDI--RARKLKQDLPGHAD 354 + TG F GH DV +++S D+R ++SGS+D T+K+W+ + + GH + Sbjct: 92 DLNTGTTTRRFVGHTKDVLSVAFSVDNRQIVSGSRDKTIKLWNTLGECKYTIGEPEGHTE 151 Query: 355 EVYAVDWSP--DGEKVVSGGKDRALKLW 432 V V +SP +VSGG D+ +K+W Sbjct: 152 WVSCVRFSPMTTNPIIVSGGWDKMVKVW 179 Score = 73.2 bits (178), Expect = 6e-13 Identities = 43/126 (34%), Positives = 63/126 (50%), Gaps = 7/126 (5%) Frame = +1 Query: 76 KARMTGHQKVVNHVY--FSPDGQWLASASFDKSVKLW-----NGITGKFVTAFRGHVADV 234 +A + GH V + P L SAS DKSV +W G A RGH V Sbjct: 8 RATLKGHTNWVTAIATPLDPSSNTLLSASRDKSVLVWELERSESNYGYARKALRGHSHFV 67 Query: 235 YQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKD 414 + S+D + L+GS D TL++WD+ + GH +V +V +S D ++VSG +D Sbjct: 68 QDVVISSDGQFCLTGSWDGTLRLWDLNTGTTTRRFVGHTKDVLSVAFSVDNRQIVSGSRD 127 Query: 415 RALKLW 432 + +KLW Sbjct: 128 KTIKLW 133 Score = 62.0 bits (149), Expect = 1e-09 Identities = 45/149 (30%), Positives = 66/149 (44%), Gaps = 9/149 (6%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 +VSG D + +W T K K + GH VN V SPDG AS D LW+ Sbjct: 167 IVSGGWDKMVKVWNLTNCKL-KNNLVGHHGYVNTVTVSPDGSLCASGGKDGIAMLWDLAE 225 Query: 193 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGH-------A 351 GK + + DV + +R L + S++K+WD+ ++ + DL A Sbjct: 226 GKRLYSL--DAGDVIHCLCFSPNRYWLCAATQSSIKIWDLESKSIVDDLRPEFNITSKKA 283 Query: 352 DEVYAVD--WSPDGEKVVSGGKDRALKLW 432 Y V WS DG + SG D +++W Sbjct: 284 QVPYCVSLAWSADGSTLYSGYTDGQIRVW 312 Score = 56.2 bits (134), Expect = 7e-08 Identities = 43/144 (29%), Positives = 64/144 (44%), Gaps = 3/144 (2%) Frame = +1 Query: 10 RLVSGSDDFTMFLWEPTIS-KQPKARMTGHQKVVNHVYFSP--DGQWLASASFDKSVKLW 180 ++VSGS D T+ LW K GH + V+ V FSP + S +DK VK+W Sbjct: 120 QIVSGSRDKTIKLWNTLGECKYTIGEPEGHTEWVSCVRFSPMTTNPIIVSGGWDKMVKVW 179 Query: 181 NGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEV 360 N K GH V ++ S D L SG KD +WD+ K L D + Sbjct: 180 NLTNCKLKNNLVGHHGYVNTVTVSPDGSLCASGGKDGIAMLWDLAEGKRLYSLDA-GDVI 238 Query: 361 YAVDWSPDGEKVVSGGKDRALKLW 432 + + +SP+ + ++K+W Sbjct: 239 HCLCFSPN-RYWLCAATQSSIKIW 261 Score = 45.1 bits (105), Expect = 2e-04 Identities = 30/107 (28%), Positives = 52/107 (48%), Gaps = 9/107 (8%) Frame = +1 Query: 19 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWN----- 183 SG D LW+ K+ + G V++ + FSP+ WL +A+ S+K+W+ Sbjct: 211 SGGKDGIAMLWDLAEGKRLYSLDAGD--VIHCLCFSPNRYWLCAAT-QSSIKIWDLESKS 267 Query: 184 ---GITGKF-VTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDI 312 + +F +T+ + V ++WSAD L SG D ++VW + Sbjct: 268 IVDDLRPEFNITSKKAQVPYCVSLAWSADGSTLYSGYTDGQIRVWAV 314
>GBLP_TOBAC (P49026) Guanine nucleotide-binding protein beta subunit-like| protein Length = 326 Score = 85.5 bits (210), Expect = 1e-16 Identities = 48/148 (32%), Positives = 79/148 (53%), Gaps = 8/148 (5%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQ----PKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLW 180 +V+ S D ++ +W T P+ R+TGH V V S DG + S S+D ++LW Sbjct: 32 IVTSSRDKSIIVWSITKDGPQYGVPRRRLTGHGHFVQDVVLSSDGMFALSGSWDGELRLW 91 Query: 181 NGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDI--RARKLKQDLPGHAD 354 + G F GH DV +++S D+R ++S S+D ++++W+ + QD H+D Sbjct: 92 DLQAGTTARRFVGHTKDVLSVAFSVDNRQIVSASRDKSIRLWNTLGECKYTIQDGDSHSD 151 Query: 355 EVYAVDWSPDG--EKVVSGGKDRALKLW 432 V V +SP+ +VSG DR +K+W Sbjct: 152 WVSCVRFSPNNLQPTIVSGSWDRTVKIW 179 Score = 59.7 bits (143), Expect = 7e-09 Identities = 43/158 (27%), Positives = 74/158 (46%), Gaps = 18/158 (11%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 +VSGS D T+ +W T K + + GH VN SPDG AS D + LW+ Sbjct: 167 IVSGSWDRTVKIWNLTNCKL-RLTLAGHTGYVNTPAVSPDGSLCASGGKDGVILLWDLAE 225 Query: 193 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLP---------- 342 GK + + + ++ + +S + R L + +S++K+WD+ ++ + DL Sbjct: 226 GKKLYSLESG-SIIHSLCFSPN-RYWLCAATESSIKIWDLESKSIVDDLKVDLKQESEMS 283 Query: 343 ------GHADEVY--AVDWSPDGEKVVSGGKDRALKLW 432 G +Y ++ WS DG + SG D +++W Sbjct: 284 SEGTASGKNKVIYCTSLSWSADGSTLFSGYTDGLIRVW 321 Score = 51.6 bits (122), Expect = 2e-06 Identities = 40/145 (27%), Positives = 68/145 (46%), Gaps = 4/145 (2%) Frame = +1 Query: 10 RLVSGSDDFTMFLWEPTISKQPKARMTG--HQKVVNHVYFSPDG--QWLASASFDKSVKL 177 ++VS S D ++ LW T+ + G H V+ V FSP+ + S S+D++VK+ Sbjct: 120 QIVSASRDKSIRLWN-TLGECKYTIQDGDSHSDWVSCVRFSPNNLQPTIVSGSWDRTVKI 178 Query: 178 WNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADE 357 WN K GH V + S D L SG KD + +WD+ K L Sbjct: 179 WNLTNCKLRLTLAGHTGYVNTPAVSPDGSLCASGGKDGVILLWDLAEGKKLYSLES-GSI 237 Query: 358 VYAVDWSPDGEKVVSGGKDRALKLW 432 ++++ +SP+ + + ++K+W Sbjct: 238 IHSLCFSPN-RYWLCAATESSIKIW 261 Score = 45.1 bits (105), Expect = 2e-04 Identities = 29/116 (25%), Positives = 53/116 (45%), Gaps = 18/116 (15%) Frame = +1 Query: 19 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWN----- 183 SG D + LW+ K+ + +G +++ + FSP+ WL +A+ + S+K+W+ Sbjct: 211 SGGKDGVILLWDLAEGKKLYSLESG--SIIHSLCFSPNRYWLCAAT-ESSIKIWDLESKS 267 Query: 184 -------------GITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDI 312 ++ + + + V +SWSAD L SG D ++VW I Sbjct: 268 IVDDLKVDLKQESEMSSEGTASGKNKVIYCTSLSWSADGSTLFSGYTDGLIRVWGI 323
>GBLP_CAEEL (Q21215) Guanine nucleotide-binding protein beta subunit 2-like 1| Length = 324 Score = 85.1 bits (209), Expect = 1e-16 Identities = 51/151 (33%), Positives = 83/151 (54%), Gaps = 11/151 (7%) Frame = +1 Query: 13 LVSGSDDFTMFLWE----PTISKQPKAR----MTGHQKVVNHVYFSPDGQWLASASFDKS 168 ++S S D T+ +W+ + + P R +TGH V+ V S DGQ+ S S+DK+ Sbjct: 32 VLSSSRDKTILVWDVDSVAPVDEGPIGRPVRSLTGHNHFVSDVVISSDGQFALSGSWDKT 91 Query: 169 VKLWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRAR-KLKQDLPG 345 ++LW+ G F H DV +++SAD+R ++SGS+D ++K+W+ A+ K Sbjct: 92 LRLWDLNQGVSTRQFISHTKDVLSVAFSADNRQIVSGSRDKSIKLWNTLAQCKYTITDDC 151 Query: 346 HADEVYAVDWSPDGEK--VVSGGKDRALKLW 432 H D V V +SP +VS G D+ +K+W Sbjct: 152 HTDWVSTVRFSPSNRDPVIVSAGWDKVVKVW 182 Score = 61.6 bits (148), Expect = 2e-09 Identities = 42/127 (33%), Positives = 62/127 (48%), Gaps = 2/127 (1%) Frame = +1 Query: 10 RLVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQ--WLASASFDKSVKLWN 183 ++VSGS D ++ LW + H V+ V FSP + + SA +DK VK+WN Sbjct: 124 QIVSGSRDKSIKLWNTLAQCKYTITDDCHTDWVSTVRFSPSNRDPVIVSAGWDKVVKVWN 183 Query: 184 GITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVY 363 + T GH V ++ S D L SG KD +WD+ K LPG+ D + Sbjct: 184 LGNCRLKTNHIGHTGYVNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLPGN-DVIN 242 Query: 364 AVDWSPD 384 A+ +SP+ Sbjct: 243 AMSFSPN 249 Score = 54.7 bits (130), Expect = 2e-07 Identities = 35/129 (27%), Positives = 59/129 (45%), Gaps = 10/129 (7%) Frame = +1 Query: 76 KARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSA 255 K GH VN V SPDG AS D LW+ GK + G+ DV + Sbjct: 190 KTNHIGHTGYVNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLPGN--DVINAMSFS 247 Query: 256 DSRLLLSGSKDSTLKVWDIRARKLKQDLP----------GHADEVYAVDWSPDGEKVVSG 405 +R L + S++K+WD+ +K ++L G + + ++ WS DG+ + +G Sbjct: 248 PNRYWLCAAVGSSIKIWDLEDKKEIEELKPEIASSGSSRGSSPQCISLAWSQDGQTLFAG 307 Query: 406 GKDRALKLW 432 D ++++ Sbjct: 308 YTDNIIRVY 316 Score = 42.0 bits (97), Expect = 0.001 Identities = 29/90 (32%), Positives = 41/90 (45%), Gaps = 11/90 (12%) Frame = +1 Query: 196 KFVTAFRGHVADVYQISWSA--DSRLLLSGSKDSTLKVWDIRA---------RKLKQDLP 342 K GH V QI+ D +LS S+D T+ VWD+ + + + L Sbjct: 6 KLTGTLEGHTGWVTQIATYTRNDKTTVLSSSRDKTILVWDVDSVAPVDEGPIGRPVRSLT 65 Query: 343 GHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 GH V V S DG+ +SG D+ L+LW Sbjct: 66 GHNHFVSDVVISSDGQFALSGSWDKTLRLW 95
>TAF5_DROME (P49846) Transcription initiation factor TFIID subunit 5| (Transcription initiation factor TFIID 85 kDa subunit) (p85) (TAFII-80) Length = 704 Score = 85.1 bits (209), Expect = 1e-16 Identities = 50/139 (35%), Positives = 71/139 (51%) Frame = +1 Query: 16 VSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITG 195 VS S D T LW T S Q GH V+ V F P+ ++A+ S D++V+LW+ +TG Sbjct: 508 VSCSYDKTARLWA-TDSNQALRVFVGHLSDVDCVQFHPNSNYVATGSSDRTVRLWDNMTG 566 Query: 196 KFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDW 375 + V GH V +++SA R L SGS D + +WD+ L L H V + + Sbjct: 567 QSVRLMTGHKGSVSSLAFSACGRYLASGSVDHNIIIWDLSNGSLVTTLLRHTSTVTTITF 626 Query: 376 SPDGEKVVSGGKDRALKLW 432 S DG + + G D L LW Sbjct: 627 SRDGTVLAAAGLDNNLTLW 645 Score = 73.6 bits (179), Expect = 4e-13 Identities = 41/140 (29%), Positives = 73/140 (52%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 L+S S+D T+ LW ++ GH V V F+P G + S S+DK+ +LW + Sbjct: 465 LLSCSEDSTIRLWS-LLTWSCVVTYRGHVYPVWDVRFAPHGYYFVSCSYDKTARLWATDS 523 Query: 193 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVD 372 + + F GH++DV + + +S + +GS D T+++WD + + + GH V ++ Sbjct: 524 NQALRVFVGHLSDVDCVQFHPNSNYVATGSSDRTVRLWDNMTGQSVRLMTGHKGSVSSLA 583 Query: 373 WSPDGEKVVSGGKDRALKLW 432 +S G + SG D + +W Sbjct: 584 FSACGRYLASGSVDHNIIIW 603 Score = 71.6 bits (174), Expect = 2e-12 Identities = 35/118 (29%), Positives = 60/118 (50%) Frame = +1 Query: 85 MTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSR 264 + GH V F+P+ L S S D +++LW+ +T V +RGHV V+ + ++ Sbjct: 446 LMGHTGPVYRCAFAPEMNLLLSCSEDSTIRLWSLLTWSCVVTYRGHVYPVWDVRFAPHGY 505 Query: 265 LLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLWMN 438 +S S D T ++W + + + GH +V V + P+ V +G DR ++LW N Sbjct: 506 YFVSCSYDKTARLWATDSNQALRVFVGHLSDVDCVQFHPNSNYVATGSSDRTVRLWDN 563 Score = 64.3 bits (155), Expect = 3e-10 Identities = 34/99 (34%), Positives = 56/99 (56%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 + +GS D T+ LW+ ++ Q MTGH+ V+ + FS G++LAS S D ++ +W+ Sbjct: 549 VATGSSDRTVRLWD-NMTGQSVRLMTGHKGSVSSLAFSACGRYLASGSVDHNIIIWDLSN 607 Query: 193 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWD 309 G VT H + V I++S D +L + D+ L +WD Sbjct: 608 GSLVTTLLRHTSTVTTITFSRDGTVLAAAGLDNNLTLWD 646 Score = 55.5 bits (132), Expect = 1e-07 Identities = 29/97 (29%), Positives = 51/97 (52%) Frame = +1 Query: 142 LASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRAR 321 L S D +V++ + +G+ + GH VY+ +++ + LLLS S+DST+++W + Sbjct: 423 LDKESADINVRMLDDRSGEVTRSLMGHTGPVYRCAFAPEMNLLLSCSEDSTIRLWSLLTW 482 Query: 322 KLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 GH V+ V ++P G VS D+ +LW Sbjct: 483 SCVVTYRGHVYPVWDVRFAPHGYYFVSCSYDKTARLW 519
>LIS1_RAT (P63004) Platelet-activating factor acetylhydrolase IB alpha| subunit (PAF acetylhydrolase 45 kDa subunit) (PAF-AH 45 kDa subunit) (PAF-AH alpha) (PAFAH alpha) (Lissencephaly-1 protein) (LIS-1) Length = 409 Score = 84.7 bits (208), Expect = 2e-16 Identities = 41/119 (34%), Positives = 66/119 (55%) Frame = +1 Query: 76 KARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSA 255 K ++GH+ V V F P + SAS D ++K+W+ TG F +GH V IS+ Sbjct: 100 KYALSGHRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLKGHTDSVQDISFDH 159 Query: 256 DSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 +LL S S D T+K+WD + + + + GH V +V P+G+ +VS +D+ +K+W Sbjct: 160 SGKLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMW 218 Score = 77.8 bits (190), Expect = 2e-14 Identities = 48/160 (30%), Positives = 76/160 (47%), Gaps = 20/160 (12%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 L S S D T+ LW+ + + M GH V+ V P+G + SAS DK++K+W T Sbjct: 164 LASCSADMTIKLWDFQGFECIRT-MHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQT 222 Query: 193 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVD 372 G V F GH V + + D L+ S S D T++VW + ++ K +L H V + Sbjct: 223 GYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVWVVATKECKAELREHEHVVECIS 282 Query: 373 WSPD--------------------GEKVVSGGKDRALKLW 432 W+P+ G ++SG +D+ +K+W Sbjct: 283 WAPESSYSSISEATGSETKKSGKPGPFLLSGSRDKTIKMW 322 Score = 70.1 bits (170), Expect = 5e-12 Identities = 37/141 (26%), Positives = 72/141 (51%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 +VS S+D T+ +W+ + + GH V + F G+ LAS S D ++KLW+ Sbjct: 122 MVSASEDATIKVWDYETGDFERT-LKGHTDSVQDISFDHSGKLLASCSADMTIKLWDFQG 180 Query: 193 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVD 372 + + GH +V ++ + ++S S+D T+K+W+++ + GH + V V Sbjct: 181 FECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQTGYCVKTFTGHREWVRMVR 240 Query: 373 WSPDGEKVVSGGKDRALKLWM 435 + DG + S D+ +++W+ Sbjct: 241 PNQDGTLIASCSNDQTVRVWV 261 Score = 69.7 bits (169), Expect = 6e-12 Identities = 43/160 (26%), Positives = 79/160 (49%), Gaps = 20/160 (12%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPD-------------------- 132 + S S+D T+ +W +K+ KA + H+ VV + ++P+ Sbjct: 248 IASCSNDQTVRVWV-VATKECKAELREHEHVVECISWAPESSYSSISEATGSETKKSGKP 306 Query: 133 GQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDI 312 G +L S S DK++K+W+ TG + GH V + + + + +LS + D TL+VWD Sbjct: 307 GPFLLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDY 366 Query: 313 RARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 + ++ + L H V ++D+ VV+G D+ +K+W Sbjct: 367 KNKRCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVKVW 406 Score = 50.4 bits (119), Expect = 4e-06 Identities = 27/101 (26%), Positives = 52/101 (51%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 L+SGS D T+ +W+ + + GH V V F G+++ S + DK++++W+ Sbjct: 310 LLSGSRDKTIKMWDVSTG-MCLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDYKN 368 Query: 193 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIR 315 + + H V + + + +++GS D T+KVW+ R Sbjct: 369 KRCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVKVWECR 409
>LIS1_PANTR (Q5IS43) Platelet-activating factor acetylhydrolase IB alpha| subunit (PAF acetylhydrolase 45 kDa subunit) (PAF-AH 45 kDa subunit) (PAF-AH alpha) (PAFAH alpha) (Lissencephaly-1 protein) (LIS-1) Length = 409 Score = 84.7 bits (208), Expect = 2e-16 Identities = 41/119 (34%), Positives = 66/119 (55%) Frame = +1 Query: 76 KARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSA 255 K ++GH+ V V F P + SAS D ++K+W+ TG F +GH V IS+ Sbjct: 100 KYALSGHRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLKGHTDSVQDISFDH 159 Query: 256 DSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 +LL S S D T+K+WD + + + + GH V +V P+G+ +VS +D+ +K+W Sbjct: 160 SGKLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMW 218 Score = 77.8 bits (190), Expect = 2e-14 Identities = 48/160 (30%), Positives = 76/160 (47%), Gaps = 20/160 (12%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 L S S D T+ LW+ + + M GH V+ V P+G + SAS DK++K+W T Sbjct: 164 LASCSADMTIKLWDFQGFECIRT-MHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQT 222 Query: 193 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVD 372 G V F GH V + + D L+ S S D T++VW + ++ K +L H V + Sbjct: 223 GYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVWVVATKECKAELREHEHVVECIS 282 Query: 373 WSPD--------------------GEKVVSGGKDRALKLW 432 W+P+ G ++SG +D+ +K+W Sbjct: 283 WAPESSYSSISEATGSETKKSGKPGPFLLSGSRDKTIKMW 322 Score = 70.1 bits (170), Expect = 5e-12 Identities = 37/141 (26%), Positives = 72/141 (51%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 +VS S+D T+ +W+ + + GH V + F G+ LAS S D ++KLW+ Sbjct: 122 MVSASEDATIKVWDYETGDFERT-LKGHTDSVQDISFDHSGKLLASCSADMTIKLWDFQG 180 Query: 193 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVD 372 + + GH +V ++ + ++S S+D T+K+W+++ + GH + V V Sbjct: 181 FECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQTGYCVKTFTGHREWVRMVR 240 Query: 373 WSPDGEKVVSGGKDRALKLWM 435 + DG + S D+ +++W+ Sbjct: 241 PNQDGTLIASCSNDQTVRVWV 261 Score = 68.6 bits (166), Expect = 1e-11 Identities = 43/160 (26%), Positives = 79/160 (49%), Gaps = 20/160 (12%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPD-------------------- 132 + S S+D T+ +W +K+ KA + H+ VV + ++P+ Sbjct: 248 IASCSNDQTVRVWV-VATKECKAELREHEHVVECISWAPESSYSSISEATGSETKKSGKP 306 Query: 133 GQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDI 312 G +L S S DK++K+W+ TG + GH V + + + + +LS + D TL+VWD Sbjct: 307 GPFLLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDY 366 Query: 313 RARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 + ++ + L H V ++D+ VV+G D+ +K+W Sbjct: 367 KNKRCMKTLNAHEHFVTSLDFHKTAPYVVTGFVDQTVKVW 406 Score = 48.1 bits (113), Expect = 2e-05 Identities = 26/101 (25%), Positives = 51/101 (50%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 L+SGS D T+ +W+ + + GH V V F G+++ S + DK++++W+ Sbjct: 310 LLSGSRDKTIKMWDVSTG-MCLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDYKN 368 Query: 193 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIR 315 + + H V + + + +++G D T+KVW+ R Sbjct: 369 KRCMKTLNAHEHFVTSLDFHKTAPYVVTGFVDQTVKVWECR 409
>LIS1_MOUSE (P63005) Platelet-activating factor acetylhydrolase IB alpha| subunit (PAF acetylhydrolase 45 kDa subunit) (PAF-AH 45 kDa subunit) (PAF-AH alpha) (PAFAH alpha) (Lissencephaly-1 protein) (LIS-1) Length = 409 Score = 84.7 bits (208), Expect = 2e-16 Identities = 41/119 (34%), Positives = 66/119 (55%) Frame = +1 Query: 76 KARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSA 255 K ++GH+ V V F P + SAS D ++K+W+ TG F +GH V IS+ Sbjct: 100 KYALSGHRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLKGHTDSVQDISFDH 159 Query: 256 DSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 +LL S S D T+K+WD + + + + GH V +V P+G+ +VS +D+ +K+W Sbjct: 160 SGKLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMW 218 Score = 77.8 bits (190), Expect = 2e-14 Identities = 48/160 (30%), Positives = 76/160 (47%), Gaps = 20/160 (12%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 L S S D T+ LW+ + + M GH V+ V P+G + SAS DK++K+W T Sbjct: 164 LASCSADMTIKLWDFQGFECIRT-MHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQT 222 Query: 193 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVD 372 G V F GH V + + D L+ S S D T++VW + ++ K +L H V + Sbjct: 223 GYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVWVVATKECKAELREHEHVVECIS 282 Query: 373 WSPD--------------------GEKVVSGGKDRALKLW 432 W+P+ G ++SG +D+ +K+W Sbjct: 283 WAPESSYSSISEATGSETKKSGKPGPFLLSGSRDKTIKMW 322 Score = 70.1 bits (170), Expect = 5e-12 Identities = 37/141 (26%), Positives = 72/141 (51%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 +VS S+D T+ +W+ + + GH V + F G+ LAS S D ++KLW+ Sbjct: 122 MVSASEDATIKVWDYETGDFERT-LKGHTDSVQDISFDHSGKLLASCSADMTIKLWDFQG 180 Query: 193 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVD 372 + + GH +V ++ + ++S S+D T+K+W+++ + GH + V V Sbjct: 181 FECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQTGYCVKTFTGHREWVRMVR 240 Query: 373 WSPDGEKVVSGGKDRALKLWM 435 + DG + S D+ +++W+ Sbjct: 241 PNQDGTLIASCSNDQTVRVWV 261 Score = 69.7 bits (169), Expect = 6e-12 Identities = 43/160 (26%), Positives = 79/160 (49%), Gaps = 20/160 (12%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPD-------------------- 132 + S S+D T+ +W +K+ KA + H+ VV + ++P+ Sbjct: 248 IASCSNDQTVRVWV-VATKECKAELREHEHVVECISWAPESSYSSISEATGSETKKSGKP 306 Query: 133 GQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDI 312 G +L S S DK++K+W+ TG + GH V + + + + +LS + D TL+VWD Sbjct: 307 GPFLLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDY 366 Query: 313 RARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 + ++ + L H V ++D+ VV+G D+ +K+W Sbjct: 367 KNKRCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVKVW 406 Score = 50.4 bits (119), Expect = 4e-06 Identities = 27/101 (26%), Positives = 52/101 (51%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 L+SGS D T+ +W+ + + GH V V F G+++ S + DK++++W+ Sbjct: 310 LLSGSRDKTIKMWDVSTG-MCLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDYKN 368 Query: 193 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIR 315 + + H V + + + +++GS D T+KVW+ R Sbjct: 369 KRCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVKVWECR 409
>LIS1_HUMAN (P43034) Platelet-activating factor acetylhydrolase IB alpha| subunit (PAF acetylhydrolase 45 kDa subunit) (PAF-AH 45 kDa subunit) (PAF-AH alpha) (PAFAH alpha) (Lissencephaly-1 protein) (LIS-1) Length = 409 Score = 84.7 bits (208), Expect = 2e-16 Identities = 41/119 (34%), Positives = 66/119 (55%) Frame = +1 Query: 76 KARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSA 255 K ++GH+ V V F P + SAS D ++K+W+ TG F +GH V IS+ Sbjct: 100 KYALSGHRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLKGHTDSVQDISFDH 159 Query: 256 DSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 +LL S S D T+K+WD + + + + GH V +V P+G+ +VS +D+ +K+W Sbjct: 160 SGKLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMW 218 Score = 77.8 bits (190), Expect = 2e-14 Identities = 48/160 (30%), Positives = 76/160 (47%), Gaps = 20/160 (12%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 L S S D T+ LW+ + + M GH V+ V P+G + SAS DK++K+W T Sbjct: 164 LASCSADMTIKLWDFQGFECIRT-MHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQT 222 Query: 193 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVD 372 G V F GH V + + D L+ S S D T++VW + ++ K +L H V + Sbjct: 223 GYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVWVVATKECKAELREHEHVVECIS 282 Query: 373 WSPD--------------------GEKVVSGGKDRALKLW 432 W+P+ G ++SG +D+ +K+W Sbjct: 283 WAPESSYSSISEATGSETKKSGKPGPFLLSGSRDKTIKMW 322 Score = 70.1 bits (170), Expect = 5e-12 Identities = 37/141 (26%), Positives = 72/141 (51%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 +VS S+D T+ +W+ + + GH V + F G+ LAS S D ++KLW+ Sbjct: 122 MVSASEDATIKVWDYETGDFERT-LKGHTDSVQDISFDHSGKLLASCSADMTIKLWDFQG 180 Query: 193 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVD 372 + + GH +V ++ + ++S S+D T+K+W+++ + GH + V V Sbjct: 181 FECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQTGYCVKTFTGHREWVRMVR 240 Query: 373 WSPDGEKVVSGGKDRALKLWM 435 + DG + S D+ +++W+ Sbjct: 241 PNQDGTLIASCSNDQTVRVWV 261 Score = 69.7 bits (169), Expect = 6e-12 Identities = 43/160 (26%), Positives = 79/160 (49%), Gaps = 20/160 (12%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPD-------------------- 132 + S S+D T+ +W +K+ KA + H+ VV + ++P+ Sbjct: 248 IASCSNDQTVRVWV-VATKECKAELREHEHVVECISWAPESSYSSISEATGSETKKSGKP 306 Query: 133 GQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDI 312 G +L S S DK++K+W+ TG + GH V + + + + +LS + D TL+VWD Sbjct: 307 GPFLLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDY 366 Query: 313 RARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 + ++ + L H V ++D+ VV+G D+ +K+W Sbjct: 367 KNKRCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVKVW 406 Score = 50.4 bits (119), Expect = 4e-06 Identities = 27/101 (26%), Positives = 52/101 (51%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 L+SGS D T+ +W+ + + GH V V F G+++ S + DK++++W+ Sbjct: 310 LLSGSRDKTIKMWDVSTG-MCLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDYKN 368 Query: 193 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIR 315 + + H V + + + +++GS D T+KVW+ R Sbjct: 369 KRCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVKVWECR 409
>WS17_SCHMA (Q26544) WD-repeat protein SL1-17| Length = 301 Score = 84.3 bits (207), Expect = 2e-16 Identities = 40/117 (34%), Positives = 72/117 (61%), Gaps = 1/117 (0%) Frame = +1 Query: 85 MTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVT-AFRGHVADVYQISWSADS 261 + GH V V FSPDG+ LASAS DK +K+++ G+ V + GH V + +++D+ Sbjct: 182 LDGHATPVRSVSFSPDGRLLASASDDKQIKVFDVRDGRLVIPSLNGHKGWVVSVDFASDN 241 Query: 262 RLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 R L++ S D ++++WD+ +++ K H D+V+ +SP G ++S G DR++ ++ Sbjct: 242 RHLVTASTDCSVRIWDLASKEEKHCFNTHEDQVWCARYSPQGNNIISVGDDRSIMIY 298 Score = 60.8 bits (146), Expect = 3e-09 Identities = 37/132 (28%), Positives = 67/132 (50%), Gaps = 1/132 (0%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISK-QPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGI 189 +++GS D + WE T S+ + + GH+ V V + G AS+S D + LW+ Sbjct: 32 IITGSLDNGLIAWEWTNSQLKCLYQFEGHRLGVISVDINSTGTLAASSSLDSQILLWDLE 91 Query: 190 TGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAV 369 TG+ + G AD + I++S DSR L +GS + + +++ + + + VY + Sbjct: 92 TGRLTKTYDGDPADTWTIAFSPDSRFLATGSHTGCVNMINVQTAQKEGSIQLEGKFVYXL 151 Query: 370 DWSPDGEKVVSG 405 + DG K+ +G Sbjct: 152 AYISDGSKLAAG 163 Score = 37.7 bits (86), Expect = 0.027 Identities = 24/98 (24%), Positives = 47/98 (47%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 L S SDD + +++ + + GH+ V V F+ D + L +AS D SV++W+ + Sbjct: 201 LASASDDKQIKVFDVRDGRLVIPSLNGHKGWVVSVDFASDNRHLVTASTDCSVRIWDLAS 260 Query: 193 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVW 306 + F H V+ +S ++S D ++ ++ Sbjct: 261 KEEKHCFNTHEDQVWCARYSPQGNNIISVGDDRSIMIY 298 Score = 29.6 bits (65), Expect = 7.2 Identities = 19/79 (24%), Positives = 35/79 (44%), Gaps = 6/79 (7%) Frame = +1 Query: 214 RGHVADVYQISW----SADSRLLLSGSKDSTLKVWDIRARKLK--QDLPGHADEVYAVDW 375 + H ++ +W + + + +++GS D+ L W+ +LK GH V +VD Sbjct: 10 QAHKEGIWCCTWGENRNRNKQYIITGSLDNGLIAWEWTNSQLKCLYQFEGHRLGVISVDI 69 Query: 376 SPDGEKVVSGGKDRALKLW 432 + G S D + LW Sbjct: 70 NSTGTLAASSSLDSQILLW 88
>LIS1_CAEEL (Q9NDC9) Lissencephaly-1 homolog (Pronuclear migration abnormal| protein 1) Length = 404 Score = 84.3 bits (207), Expect = 2e-16 Identities = 54/159 (33%), Positives = 77/159 (48%), Gaps = 15/159 (9%) Frame = +1 Query: 1 APXRLVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLW 180 A +LVS S D ++ LW+ + + GH+ V+ V F P G ++ SAS D ++K W Sbjct: 159 AGKQLVSCSSDLSIKLWDFGQTYDCLKSLKGHEHTVSSVTFLPTGDFVLSASRDHTIKQW 218 Query: 181 NGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEV 360 + TG V FRGH V I S D L S S D T+ VW + K L H V Sbjct: 219 DISTGYCVYTFRGHNDWVRMIRISNDGTLFASASLDQTVTVWSFATKSAKLVLRDHEHAV 278 Query: 361 YAVDWSPD-------GEK--------VVSGGKDRALKLW 432 V+W+PD G++ + SG +DR++K W Sbjct: 279 ECVEWAPDTAYTNVTGQQPEGNSTHILFSGSRDRSIKAW 317 Score = 71.6 bits (174), Expect = 2e-12 Identities = 38/118 (32%), Positives = 63/118 (53%), Gaps = 1/118 (0%) Frame = +1 Query: 82 RMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADS 261 ++TGH+ + V F P +AS S D ++K+W+ TG+ +GH V I+ A Sbjct: 101 KLTGHRLPITRVIFHPLWTIMASCSEDATIKVWDYETGQLERTLKGHTDAVNDIAIDAAG 160 Query: 262 RLLLSGSKDSTLKVWDI-RARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 + L+S S D ++K+WD + + L GH V +V + P G+ V+S +D +K W Sbjct: 161 KQLVSCSSDLSIKLWDFGQTYDCLKSLKGHEHTVSSVTFLPTGDFVLSASRDHTIKQW 218 Score = 69.3 bits (168), Expect = 8e-12 Identities = 43/141 (30%), Positives = 67/141 (47%), Gaps = 1/141 (0%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWN-GI 189 + S S+D T+ +W+ Q + + GH VN + G+ L S S D S+KLW+ G Sbjct: 121 MASCSEDATIKVWDYETG-QLERTLKGHTDAVNDIAIDAAGKQLVSCSSDLSIKLWDFGQ 179 Query: 190 TGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAV 369 T + + +GH V +++ +LS S+D T+K WDI GH D V + Sbjct: 180 TYDCLKSLKGHEHTVSSVTFLPTGDFVLSASRDHTIKQWDISTGYCVYTFRGHNDWVRMI 239 Query: 370 DWSPDGEKVVSGGKDRALKLW 432 S DG S D+ + +W Sbjct: 240 RISNDGTLFASASLDQTVTVW 260 Score = 58.5 bits (140), Expect = 1e-08 Identities = 40/153 (26%), Positives = 69/153 (45%), Gaps = 15/153 (9%) Frame = +1 Query: 19 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQW---------------LASA 153 S S D T+ +W +K K + H+ V V ++PD + L S Sbjct: 250 SASLDQTVTVWS-FATKSAKLVLRDHEHAVECVEWAPDTAYTNVTGQQPEGNSTHILFSG 308 Query: 154 SFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQ 333 S D+S+K WN TG + H V +++ + L+S + D TL+VW++ A++ + Sbjct: 309 SRDRSIKAWNINTGDVLFTLLAHENWVRGLAFHPKGKYLISVADDKTLRVWELSAQRCMK 368 Query: 334 DLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 + H V V + V++G D + K+W Sbjct: 369 AIEAHEHFVSTVAFHQTSPFVITGSVDMSCKVW 401 Score = 47.0 bits (110), Expect = 4e-05 Identities = 27/101 (26%), Positives = 49/101 (48%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 L SGS D ++ W + H+ V + F P G++L S + DK++++W Sbjct: 305 LFSGSRDRSIKAWNINTG-DVLFTLLAHENWVRGLAFHPKGKYLISVADDKTLRVWELSA 363 Query: 193 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIR 315 + + A H V +++ S +++GS D + KVW+ R Sbjct: 364 QRCMKAIEAHEHFVSTVAFHQTSPFVITGSVDMSCKVWECR 404
>LIS1_BOVIN (P43033) Platelet-activating factor acetylhydrolase IB alpha| subunit (PAF acetylhydrolase 45 kDa subunit) (PAF-AH 45 kDa subunit) (PAF-AH alpha) (PAFAH alpha) (Lissencephaly-1 protein) (LIS-1) Length = 409 Score = 84.3 bits (207), Expect = 2e-16 Identities = 41/119 (34%), Positives = 66/119 (55%) Frame = +1 Query: 76 KARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSA 255 K ++GH+ V V F P + SAS D ++K+W+ TG F +GH V IS+ Sbjct: 100 KYALSGHRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLKGHTDSVEDISFDH 159 Query: 256 DSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 +LL S S D T+K+WD + + + + GH V +V P+G+ +VS +D+ +K+W Sbjct: 160 SGKLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMW 218 Score = 77.8 bits (190), Expect = 2e-14 Identities = 48/160 (30%), Positives = 76/160 (47%), Gaps = 20/160 (12%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 L S S D T+ LW+ + + M GH V+ V P+G + SAS DK++K+W T Sbjct: 164 LASCSADMTIKLWDFQGFECIRT-MHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQT 222 Query: 193 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVD 372 G V F GH V + + D L+ S S D T++VW + ++ K +L H V + Sbjct: 223 GYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVWVVATKECKAELREHEHVVECIS 282 Query: 373 WSPD--------------------GEKVVSGGKDRALKLW 432 W+P+ G ++SG +D+ +K+W Sbjct: 283 WAPESSYSSISEATGSETKKSGKPGPFLLSGSRDKTIKMW 322 Score = 70.1 bits (170), Expect = 5e-12 Identities = 37/141 (26%), Positives = 72/141 (51%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 +VS S+D T+ +W+ + + GH V + F G+ LAS S D ++KLW+ Sbjct: 122 MVSASEDATIKVWDYETGDFERT-LKGHTDSVEDISFDHSGKLLASCSADMTIKLWDFQG 180 Query: 193 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVD 372 + + GH +V ++ + ++S S+D T+K+W+++ + GH + V V Sbjct: 181 FECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQTGYCVKTFTGHREWVRMVR 240 Query: 373 WSPDGEKVVSGGKDRALKLWM 435 + DG + S D+ +++W+ Sbjct: 241 PNQDGTLIASCSNDQTVRVWV 261 Score = 69.7 bits (169), Expect = 6e-12 Identities = 43/160 (26%), Positives = 79/160 (49%), Gaps = 20/160 (12%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPD-------------------- 132 + S S+D T+ +W +K+ KA + H+ VV + ++P+ Sbjct: 248 IASCSNDQTVRVWV-VATKECKAELREHEHVVECISWAPESSYSSISEATGSETKKSGKP 306 Query: 133 GQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDI 312 G +L S S DK++K+W+ TG + GH V + + + + +LS + D TL+VWD Sbjct: 307 GPFLLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDY 366 Query: 313 RARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 + ++ + L H V ++D+ VV+G D+ +K+W Sbjct: 367 KNKRCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVKVW 406 Score = 50.4 bits (119), Expect = 4e-06 Identities = 27/101 (26%), Positives = 52/101 (51%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 L+SGS D T+ +W+ + + GH V V F G+++ S + DK++++W+ Sbjct: 310 LLSGSRDKTIKMWDVSTG-MCLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDYKN 368 Query: 193 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIR 315 + + H V + + + +++GS D T+KVW+ R Sbjct: 369 KRCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVKVWECR 409
>RCO1_NEUCR (P78706) Transcriptional repressor rco-1| Length = 604 Score = 84.0 bits (206), Expect = 3e-16 Identities = 49/143 (34%), Positives = 86/143 (60%), Gaps = 3/143 (2%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 L +G++D + +W+ S+ + GH++ + + FS DG+ +AS S D++V+LW+ T Sbjct: 359 LATGAEDKLIRVWDIQ-SRTIRNTFHGHEQDIYSLDFSRDGRTIASGSGDRTVRLWDIET 417 Query: 193 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIR---ARKLKQDLPGHADEVY 363 G+ T+ V ++ S D + + +GS D +++VWD+R A +L + GH D VY Sbjct: 418 GQ-NTSVLSIEDGVTTVAISPDKQFVAAGSLDKSVRVWDMRGYLAERL-EGPDGHKDSVY 475 Query: 364 AVDWSPDGEKVVSGGKDRALKLW 432 +V +SPDG +VSG D+ +K+W Sbjct: 476 SVAFSPDGRNLVSGSLDKTIKMW 498 Score = 68.2 bits (165), Expect = 2e-11 Identities = 46/131 (35%), Positives = 66/131 (50%), Gaps = 17/131 (12%) Frame = +1 Query: 91 GHQKVVNHVYFSPDGQWLASASFDKSVKLWN-----GIT-------GKFVTAFRGHVADV 234 GH+ V V FSPDG+ L S S DK++K+W GI G+ + F GH V Sbjct: 469 GHKDSVYSVAFSPDGRNLVSGSLDKTIKMWELSAPRGIPSSAPPKGGRCIKTFEGHRDFV 528 Query: 235 YQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSP-DGEKVV---- 399 ++ + DS+ +LSGSKD ++ WD R + L GH + V +V SP G V Sbjct: 529 LSVALTPDSQWVLSGSKDRGVQFWDPRTGHTQLMLQGHKNSVISVAPSPVTGPNGVGYFA 588 Query: 400 SGGKDRALKLW 432 +G D ++W Sbjct: 589 TGSGDMRARIW 599
>YZLL_CAEEL (Q93847) Hypothetical WD-repeat protein K04G11.4| Length = 395 Score = 84.0 bits (206), Expect = 3e-16 Identities = 37/113 (32%), Positives = 68/113 (60%) Frame = +1 Query: 94 HQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLLL 273 H+K ++ + FSPDG+++ S S D S+K+W + + GH + + SWS+DS+L++ Sbjct: 106 HKKSISGIKFSPDGRYMGSGSADCSIKIWR-MDFVYEKTLMGHRLGINEFSWSSDSKLIV 164 Query: 274 SGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 S S D +KV+D+ + + + L GH + V+ ++P G + SG D +++W Sbjct: 165 SCSDDKLVKVFDVSSGRCVKTLKGHTNYVFCCCFNPSGTLIASGSFDETIRIW 217 Score = 75.1 bits (183), Expect = 2e-13 Identities = 41/138 (29%), Positives = 72/138 (52%) Frame = +1 Query: 19 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 198 SGS D ++ +W + + GH+ +N +S D + + S S DK VK+++ +G+ Sbjct: 124 SGSADCSIKIWRMDFVYEKT--LMGHRLGINEFSWSSDSKLIVSCSDDKLVKVFDVSSGR 181 Query: 199 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWS 378 V +GH V+ ++ L+ SGS D T+++W R +PGH D V +V ++ Sbjct: 182 CVKTLKGHTNYVFCCCFNPSGTLIASGSFDETIRIWCARNGNTIFSIPGHEDPVSSVCFN 241 Query: 379 PDGEKVVSGGKDRALKLW 432 DG + SG D +++W Sbjct: 242 RDGAYLASGSYDGIVRIW 259 Score = 70.1 bits (170), Expect = 5e-12 Identities = 37/146 (25%), Positives = 76/146 (52%), Gaps = 6/146 (4%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 L SGS D + +W+ T K + + HV FSP+G+++ +++ + ++KLW+ Sbjct: 247 LASGSYDGIVRIWDSTTGTCVKTLIDEEHPPITHVKFSPNGKYILASNLNNTLKLWDYQK 306 Query: 193 GKFVTAFRGHVADVYQISWS---ADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVY 363 + + + GH Y ++ + + ++SGS+D + +W+++ R++ Q L GH V Sbjct: 307 LRVLKEYTGHENSKYCVAANFSVTGGKWIVSGSEDHKVYIWNLQTREILQTLDGHNTAVM 366 Query: 364 AVDWSPDGEKVVSGG---KDRALKLW 432 D P G+ +++ D +K+W Sbjct: 367 CTDCHP-GQNIIASAALEPDMRIKIW 391 Score = 67.8 bits (164), Expect = 2e-11 Identities = 39/141 (27%), Positives = 72/141 (51%), Gaps = 1/141 (0%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 +VS SDD + +++ + + K + GH V F+P G +AS SFD+++++W Sbjct: 163 IVSCSDDKLVKVFDVSSGRCVKT-LKGHTNYVFCCCFNPSGTLIASGSFDETIRIWCARN 221 Query: 193 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWD-IRARKLKQDLPGHADEVYAV 369 G + + GH V + ++ D L SGS D +++WD +K + + V Sbjct: 222 GNTIFSIPGHEDPVSSVCFNRDGAYLASGSYDGIVRIWDSTTGTCVKTLIDEEHPPITHV 281 Query: 370 DWSPDGEKVVSGGKDRALKLW 432 +SP+G+ +++ + LKLW Sbjct: 282 KFSPNGKYILASNLNNTLKLW 302
>LIS1_MACFA (Q8HXX0) Platelet-activating factor acetylhydrolase IB alpha| subunit (PAF acetylhydrolase 45 kDa subunit) (PAF-AH 45 kDa subunit) (PAF-AH alpha) (PAFAH alpha) (Lissencephaly-1 protein) (LIS-1) Length = 409 Score = 84.0 bits (206), Expect = 3e-16 Identities = 41/119 (34%), Positives = 66/119 (55%) Frame = +1 Query: 76 KARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSA 255 K ++GH+ V V F P + SAS D ++K+W+ TG F +GH V IS+ Sbjct: 100 KYALSGHRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLKGHTDSVQDISFDH 159 Query: 256 DSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 +LL S S D T+K+WD + + + + GH V +V P+G+ +VS +D+ +K+W Sbjct: 160 SGKLLTSCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHLVSASRDKTIKMW 218 Score = 78.6 bits (192), Expect = 1e-14 Identities = 49/160 (30%), Positives = 76/160 (47%), Gaps = 20/160 (12%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 L S S D T+ LW+ + + M GH V+ V P+G L SAS DK++K+W T Sbjct: 164 LTSCSADMTIKLWDFQGFECIRT-MHGHDHNVSSVAIMPNGDHLVSASRDKTIKMWEVQT 222 Query: 193 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVD 372 G V F GH V + + D L+ S S D T++VW + ++ K +L H V + Sbjct: 223 GYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVWVVATKECKAELREHEHVVECIS 282 Query: 373 WSPD--------------------GEKVVSGGKDRALKLW 432 W+P+ G ++SG +D+ +K+W Sbjct: 283 WAPESSYSSISEATGSETKKSGKPGPFLLSGSRDKTIKMW 322 Score = 69.7 bits (169), Expect = 6e-12 Identities = 43/160 (26%), Positives = 79/160 (49%), Gaps = 20/160 (12%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPD-------------------- 132 + S S+D T+ +W +K+ KA + H+ VV + ++P+ Sbjct: 248 IASCSNDQTVRVWV-VATKECKAELREHEHVVECISWAPESSYSSISEATGSETKKSGKP 306 Query: 133 GQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDI 312 G +L S S DK++K+W+ TG + GH V + + + + +LS + D TL+VWD Sbjct: 307 GPFLLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDY 366 Query: 313 RARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 + ++ + L H V ++D+ VV+G D+ +K+W Sbjct: 367 KNKRCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVKVW 406 Score = 69.3 bits (168), Expect = 8e-12 Identities = 37/141 (26%), Positives = 71/141 (50%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 +VS S+D T+ +W+ + + GH V + F G+ L S S D ++KLW+ Sbjct: 122 MVSASEDATIKVWDYETGDFERT-LKGHTDSVQDISFDHSGKLLTSCSADMTIKLWDFQG 180 Query: 193 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVD 372 + + GH +V ++ + L+S S+D T+K+W+++ + GH + V V Sbjct: 181 FECIRTMHGHDHNVSSVAIMPNGDHLVSASRDKTIKMWEVQTGYCVKTFTGHREWVRMVR 240 Query: 373 WSPDGEKVVSGGKDRALKLWM 435 + DG + S D+ +++W+ Sbjct: 241 PNQDGTLIASCSNDQTVRVWV 261 Score = 50.4 bits (119), Expect = 4e-06 Identities = 27/101 (26%), Positives = 52/101 (51%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 L+SGS D T+ +W+ + + GH V V F G+++ S + DK++++W+ Sbjct: 310 LLSGSRDKTIKMWDVSTG-MCLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDYKN 368 Query: 193 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIR 315 + + H V + + + +++GS D T+KVW+ R Sbjct: 369 KRCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVKVWECR 409
>GBLP_BRANA (Q39336) Guanine nucleotide-binding protein beta subunit-like| protein Length = 327 Score = 83.6 bits (205), Expect = 4e-16 Identities = 48/149 (32%), Positives = 79/149 (53%), Gaps = 9/149 (6%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQP----KARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLW 180 +VS S D ++ +W+ T + + R+TGH V V S DGQ+ S S+D ++LW Sbjct: 31 IVSASRDKSIIVWKLTKDDKSYGVRQRRLTGHSHFVEDVVLSSDGQFALSGSWDGELRLW 90 Query: 181 NGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRAR---KLKQDLPGHA 351 + G F GH DV +++S D+R ++S S+D T+K+W+ + + GH Sbjct: 91 DLAAGVSTRRFVGHTKDVLSVAFSLDNRQIVSASRDRTIKLWNTLGECKYTISEGGEGHR 150 Query: 352 DEVYAVDWSPD--GEKVVSGGKDRALKLW 432 D V V +SP+ +VS D+ +K+W Sbjct: 151 DWVSCVRFSPNTLQPTIVSASCDKTVKVW 179 Score = 59.7 bits (143), Expect = 7e-09 Identities = 45/149 (30%), Positives = 75/149 (50%), Gaps = 8/149 (5%) Frame = +1 Query: 10 RLVSGSDDFTMFLWEP------TISKQPKARMTGHQKVVNHVYFSPDG--QWLASASFDK 165 ++VS S D T+ LW TIS+ + GH+ V+ V FSP+ + SAS DK Sbjct: 119 QIVSASRDRTIKLWNTLGECKYTISEGGE----GHRDWVSCVRFSPNTLQPTIVSASCDK 174 Query: 166 SVKLWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPG 345 +VK+WN K + GH V ++ S D L SG KD + +WD+ K L Sbjct: 175 TVKVWNLSNCKLRSTLAGHTGYVSTVAVSPDGSLCASGGKDGVVLLWDLAEGKKLYSLEA 234 Query: 346 HADEVYAVDWSPDGEKVVSGGKDRALKLW 432 ++ ++A+ ++P+ + ++ +K+W Sbjct: 235 NS-VIHALCFTPN-RYWLCAATEQGIKIW 261 Score = 56.2 bits (134), Expect = 7e-08 Identities = 43/159 (27%), Positives = 73/159 (45%), Gaps = 19/159 (11%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 +VS S D T+ +W + K ++ + GH V+ V SPDG AS D V LW+ Sbjct: 167 IVSASCDKTVKVWNLSNCKL-RSTLAGHTGYVSTVAVSPDGSLCASGGKDGVVLLWDLAE 225 Query: 193 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARK----LKQDLPGHADE- 357 GK + + + V +R L + + +K+WD+ ++ LK DL A++ Sbjct: 226 GKKLYSLEAN--SVIHALCFTPNRYWLCAATEQGIKIWDLESKTVVEDLKVDLKAEAEKS 283 Query: 358 ------------VY--AVDWSPDGEKVVSGGKDRALKLW 432 +Y +++WS DG + SG D +++W Sbjct: 284 DGSGTAATKRKVIYCTSLNWSADGSTLFSGYTDGVIRVW 322 Score = 41.6 bits (96), Expect = 0.002 Identities = 28/117 (23%), Positives = 50/117 (42%), Gaps = 19/117 (16%) Frame = +1 Query: 19 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWN----- 183 SG D + LW+ +++ K V++ + F+P+ WL +A+ ++ +K+W+ Sbjct: 211 SGGKDGVVLLWD--LAEGKKLYSLEANSVIHALCFTPNRYWLCAAT-EQGIKIWDLESKT 267 Query: 184 --------------GITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDI 312 G A + V ++WSAD L SG D ++VW I Sbjct: 268 VVEDLKVDLKAEAEKSDGSGTAATKRKVIYCTSLNWSADGSTLFSGYTDGVIRVWGI 324
>PRP4_HUMAN (O43172) U4/U6 small nuclear ribonucleoprotein Prp4 (U4/U6 snRNP 60| kDa protein) (WD splicing factor Prp4) (hPrp4) Length = 522 Score = 82.8 bits (203), Expect = 7e-16 Identities = 44/140 (31%), Positives = 74/140 (52%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 L S + D ++ LW S +P A + GH V V + P G++L + +D+S +LW+ Sbjct: 296 LASCAADGSVKLWSLD-SDEPVADIEGHTVRVARVMWHPSGRFLGTTCYDRSWRLWDLEA 354 Query: 193 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVD 372 + + GH VY I++ D L +G D+ +VWD+R + L GH E+Y ++ Sbjct: 355 QEEILHQEGHSMGVYDIAFHQDGSLAGTGGLDAFGRVWDLRTGRCIMFLEGHLKEIYGIN 414 Query: 373 WSPDGEKVVSGGKDRALKLW 432 +SP+G + +G D K+W Sbjct: 415 FSPNGYHIATGSGDNTCKVW 434 Score = 72.4 bits (176), Expect = 1e-12 Identities = 35/115 (30%), Positives = 60/115 (52%), Gaps = 1/115 (0%) Frame = +1 Query: 91 GHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLL 270 GH V + F DG + D ++W+ TG+ + GH+ ++Y I++S + + Sbjct: 363 GHSMGVYDIAFHQDGSLAGTGGLDAFGRVWDLRTGRCIMFLEGHLKEIYGINFSPNGYHI 422 Query: 271 LSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSP-DGEKVVSGGKDRALKLW 432 +GS D+T KVWD+R R+ +P H + V V + P G +++G D K+W Sbjct: 423 ATGSGDNTCKVWDLRQRRCVYTIPAHQNLVTGVKFEPIHGNFLLTGAYDNTAKIW 477 Score = 63.2 bits (152), Expect = 6e-10 Identities = 36/118 (30%), Positives = 58/118 (49%), Gaps = 1/118 (0%) Frame = +1 Query: 85 MTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSA-DS 261 + GH K + + FSP+G +A+ S D + K+W+ + V H V + + Sbjct: 403 LEGHLKEIYGINFSPNGYHIATGSGDNTCKVWDLRQRRCVYTIPAHQNLVTGVKFEPIHG 462 Query: 262 RLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLWM 435 LL+G+ D+T K+W + L GH +V +D S DG+ + + DR KLWM Sbjct: 463 NFLLTGAYDNTAKIWTHPGWSPLKTLAGHEGKVMGLDISSDGQLIATCSYDRTFKLWM 520 Score = 57.0 bits (136), Expect = 4e-08 Identities = 35/124 (28%), Positives = 56/124 (45%), Gaps = 8/124 (6%) Frame = +1 Query: 85 MTGHQKVVNHVYFSPDGQW--------LASASFDKSVKLWNGITGKFVTAFRGHVADVYQ 240 + GH V + F P LAS + D SVKLW+ + + V GH V + Sbjct: 269 LRGHNTNVGAIVFHPKSTVSLDPKDVNLASCAADGSVKLWSLDSDEPVADIEGHTVRVAR 328 Query: 241 ISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRA 420 + W R L + D + ++WD+ A++ GH+ VY + + DG +GG D Sbjct: 329 VMWHPSGRFLGTTCYDRSWRLWDLEAQEEILHQEGHSMGVYDIAFHQDGSLAGTGGLDAF 388 Query: 421 LKLW 432 ++W Sbjct: 389 GRVW 392 Score = 55.5 bits (132), Expect = 1e-07 Identities = 33/122 (27%), Positives = 59/122 (48%), Gaps = 8/122 (6%) Frame = +1 Query: 91 GHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRL- 267 G + +++ +FSP+ + LA+A + KLW+ + RGH +V I + S + Sbjct: 229 GDDRPISYCHFSPNSKMLATACWSGLCKLWSVPDCNLLHTLRGHNTNVGAIVFHPKSTVS 288 Query: 268 -------LLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALK 426 L S + D ++K+W + + + D+ GH V V W P G + + DR+ + Sbjct: 289 LDPKDVNLASCAADGSVKLWSLDSDEPVADIEGHTVRVARVMWHPSGRFLGTTCYDRSWR 348 Query: 427 LW 432 LW Sbjct: 349 LW 350 Score = 36.6 bits (83), Expect = 0.059 Identities = 19/56 (33%), Positives = 31/56 (55%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLW 180 L++G+ D T +W P + GH+ V + S DGQ +A+ S+D++ KLW Sbjct: 465 LLTGAYDNTAKIWTHP-GWSPLKTLAGHEGKVMGLDISSDGQLIATCSYDRTFKLW 519
>TUP11_SCHPO (Q09715) Transcriptional repressor tup11| Length = 614 Score = 82.8 bits (203), Expect = 7e-16 Identities = 56/192 (29%), Positives = 89/192 (46%), Gaps = 52/192 (27%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLW---- 180 LV+G++D + LW+ + K + +GH++ + + FS +G+++ S S D++ +LW Sbjct: 375 LVTGTEDRQIKLWDLSTQKV-RYVFSGHEQDIYSLDFSHNGRFIVSGSGDRTARLWDVET 433 Query: 181 ----------NGIT--------------------------GKFVTAFRGHVADVYQISWS 252 NG+T G V GH VY I++S Sbjct: 434 GQCILKLEIENGVTAIAISPNDQFIAVGSLDQIIRVWSVSGTLVERLEGHKESVYSIAFS 493 Query: 253 ADSRLLLSGSKDSTLKVWDIRARK------------LKQDLPGHADEVYAVDWSPDGEKV 396 DS +LLSGS D T+KVW+++A + K GH D V +V SPD Sbjct: 494 PDSSILLSGSLDKTIKVWELQATRSVGLSAIKPEGICKATYTGHTDFVLSVAVSPDSRWG 553 Query: 397 VSGGKDRALKLW 432 +SG KDR+++ W Sbjct: 554 LSGSKDRSMQFW 565 Score = 81.3 bits (199), Expect = 2e-15 Identities = 49/149 (32%), Positives = 77/149 (51%), Gaps = 12/149 (8%) Frame = +1 Query: 22 GSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWN------ 183 GS D + +W ++S R+ GH++ V + FSPD L S S DK++K+W Sbjct: 461 GSLDQIIRVW--SVSGTLVERLEGHKESVYSIAFSPDSSILLSGSLDKTIKVWELQATRS 518 Query: 184 -GIT-----GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPG 345 G++ G + GH V ++ S DSR LSGSKD +++ WD++ + G Sbjct: 519 VGLSAIKPEGICKATYTGHTDFVLSVAVSPDSRWGLSGSKDRSMQFWDLQTGQSYLTCQG 578 Query: 346 HADEVYAVDWSPDGEKVVSGGKDRALKLW 432 H + V +V +SPDG + SG D ++W Sbjct: 579 HKNSVISVCFSPDGRQFASGSGDLRARIW 607 Score = 77.4 bits (189), Expect = 3e-14 Identities = 41/149 (27%), Positives = 69/149 (46%), Gaps = 40/149 (26%) Frame = +1 Query: 106 VNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSK 285 V + FSPDG++L + + D+ +KLW+ T K F GH D+Y + +S + R ++SGS Sbjct: 363 VRTIAFSPDGKYLVTGTEDRQIKLWDLSTQKVRYVFSGHEQDIYSLDFSHNGRFIVSGSG 422 Query: 286 DSTLKVWDIRARK----------------------------------------LKQDLPG 345 D T ++WD+ + L + L G Sbjct: 423 DRTARLWDVETGQCILKLEIENGVTAIAISPNDQFIAVGSLDQIIRVWSVSGTLVERLEG 482 Query: 346 HADEVYAVDWSPDGEKVVSGGKDRALKLW 432 H + VY++ +SPD ++SG D+ +K+W Sbjct: 483 HKESVYSIAFSPDSSILLSGSLDKTIKVW 511 Score = 63.2 bits (152), Expect = 6e-10 Identities = 38/111 (34%), Positives = 54/111 (48%), Gaps = 11/111 (9%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQP-----------KARMTGHQKVVNHVYFSPDGQWLASASF 159 L+SGS D T+ +WE ++ KA TGH V V SPD +W S S Sbjct: 499 LLSGSLDKTIKVWELQATRSVGLSAIKPEGICKATYTGHTDFVLSVAVSPDSRWGLSGSK 558 Query: 160 DKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDI 312 D+S++ W+ TG+ +GH V + +S D R SGS D ++W I Sbjct: 559 DRSMQFWDLQTGQSYLTCQGHKNSVISVCFSPDGRQFASGSGDLRARIWSI 609
>PRP4_PONPY (Q5NVD0) U4/U6 small nuclear ribonucleoprotein Prp4 (U4/U6 snRNP 60| kDa protein) (WD splicing factor Prp4) Length = 521 Score = 82.8 bits (203), Expect = 7e-16 Identities = 44/140 (31%), Positives = 74/140 (52%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 L S + D ++ LW S +P A + GH V V + P G++L + +D+S +LW+ Sbjct: 295 LASCAADGSVKLWSLD-SDEPVADIEGHTVRVARVMWHPSGRFLGTTCYDRSWRLWDLEA 353 Query: 193 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVD 372 + + GH VY I++ D L +G D+ +VWD+R + L GH E+Y ++ Sbjct: 354 QEEILHQEGHSMGVYDIAFHQDGSLAGTGGLDAFGRVWDLRTGRCIMFLEGHLKEIYGIN 413 Query: 373 WSPDGEKVVSGGKDRALKLW 432 +SP+G + +G D K+W Sbjct: 414 FSPNGYHIATGSGDNTCKVW 433 Score = 72.4 bits (176), Expect = 1e-12 Identities = 35/115 (30%), Positives = 60/115 (52%), Gaps = 1/115 (0%) Frame = +1 Query: 91 GHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLL 270 GH V + F DG + D ++W+ TG+ + GH+ ++Y I++S + + Sbjct: 362 GHSMGVYDIAFHQDGSLAGTGGLDAFGRVWDLRTGRCIMFLEGHLKEIYGINFSPNGYHI 421 Query: 271 LSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSP-DGEKVVSGGKDRALKLW 432 +GS D+T KVWD+R R+ +P H + V V + P G +++G D K+W Sbjct: 422 ATGSGDNTCKVWDLRQRRCVYTIPAHQNLVTGVKFEPIHGNFLLTGAYDNTAKIW 476 Score = 63.2 bits (152), Expect = 6e-10 Identities = 36/118 (30%), Positives = 58/118 (49%), Gaps = 1/118 (0%) Frame = +1 Query: 85 MTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSA-DS 261 + GH K + + FSP+G +A+ S D + K+W+ + V H V + + Sbjct: 402 LEGHLKEIYGINFSPNGYHIATGSGDNTCKVWDLRQRRCVYTIPAHQNLVTGVKFEPIHG 461 Query: 262 RLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLWM 435 LL+G+ D+T K+W + L GH +V +D S DG+ + + DR KLWM Sbjct: 462 NFLLTGAYDNTAKIWTHPGWSPLKTLAGHEGKVMGLDISSDGQLIATCSYDRTFKLWM 519 Score = 55.5 bits (132), Expect = 1e-07 Identities = 33/122 (27%), Positives = 59/122 (48%), Gaps = 8/122 (6%) Frame = +1 Query: 91 GHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRL- 267 G + +++ +FSP+ + LA+A + KLW+ + RGH +V I + S + Sbjct: 228 GDDRPISYCHFSPNSKMLATACWSGLCKLWSVPDCNLLHTLRGHNTNVGAIVFHPKSTVS 287 Query: 268 -------LLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALK 426 L S + D ++K+W + + + D+ GH V V W P G + + DR+ + Sbjct: 288 LDQKDVNLASCAADGSVKLWSLDSDEPVADIEGHTVRVARVMWHPSGRFLGTTCYDRSWR 347 Query: 427 LW 432 LW Sbjct: 348 LW 349 Score = 36.6 bits (83), Expect = 0.059 Identities = 19/56 (33%), Positives = 31/56 (55%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLW 180 L++G+ D T +W P + GH+ V + S DGQ +A+ S+D++ KLW Sbjct: 464 LLTGAYDNTAKIWTHP-GWSPLKTLAGHEGKVMGLDISSDGQLIATCSYDRTFKLW 518
>PRP4_MOUSE (Q9DAW6) U4/U6 small nuclear ribonucleoprotein Prp4 (U4/U6 snRNP 60| kDa protein) (WD splicing factor Prp4) Length = 521 Score = 82.8 bits (203), Expect = 7e-16 Identities = 44/140 (31%), Positives = 74/140 (52%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 L S + D ++ LW S +P A + GH V V + P G++L + +D+S +LW+ Sbjct: 295 LASCAADGSVKLWSLD-SDEPVADIEGHTVRVARVMWHPSGRFLGTTCYDRSWRLWDLEA 353 Query: 193 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVD 372 + + GH VY I++ D L +G D+ +VWD+R + L GH E+Y ++ Sbjct: 354 QEEILHQEGHSMGVYDIAFHQDGSLAGTGGLDAFGRVWDLRTGRCIMFLEGHLKEIYGIN 413 Query: 373 WSPDGEKVVSGGKDRALKLW 432 +SP+G + +G D K+W Sbjct: 414 FSPNGYHIATGSGDNTCKVW 433 Score = 73.2 bits (178), Expect = 6e-13 Identities = 35/115 (30%), Positives = 61/115 (53%), Gaps = 1/115 (0%) Frame = +1 Query: 91 GHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLL 270 GH V + F DG + D ++W+ TG+ + GH+ ++Y I++S + + Sbjct: 362 GHSMGVYDIAFHQDGSLAGTGGLDAFGRVWDLRTGRCIMFLEGHLKEIYGINFSPNGYHI 421 Query: 271 LSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSP-DGEKVVSGGKDRALKLW 432 +GS D+T KVWD+R R+ +P H + V V + P G+ +++G D K+W Sbjct: 422 ATGSGDNTCKVWDLRQRRCVYTIPAHQNLVTGVKFEPIHGDFLLTGAYDNTAKIW 476 Score = 62.4 bits (150), Expect = 1e-09 Identities = 36/118 (30%), Positives = 58/118 (49%), Gaps = 1/118 (0%) Frame = +1 Query: 85 MTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSA-DS 261 + GH K + + FSP+G +A+ S D + K+W+ + V H V + + Sbjct: 402 LEGHLKEIYGINFSPNGYHIATGSGDNTCKVWDLRQRRCVYTIPAHQNLVTGVKFEPIHG 461 Query: 262 RLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLWM 435 LL+G+ D+T K+W + L GH +V +D S DG+ + + DR KLWM Sbjct: 462 DFLLTGAYDNTAKIWTHPGWSPLKTLAGHEGKVMGLDISSDGQLIATCSYDRTFKLWM 519 Score = 55.5 bits (132), Expect = 1e-07 Identities = 33/122 (27%), Positives = 59/122 (48%), Gaps = 8/122 (6%) Frame = +1 Query: 91 GHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRL- 267 G + +++ +FSP+ + LA+A + KLW+ + RGH +V I + S + Sbjct: 228 GDDRPISYCHFSPNSKMLATACWSGLCKLWSVPDCSLLHTLRGHNTNVGAIVFHPKSTVS 287 Query: 268 -------LLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALK 426 L S + D ++K+W + + + D+ GH V V W P G + + DR+ + Sbjct: 288 LDQKDVNLASCAADGSVKLWSLDSDEPVADIEGHTVRVARVMWHPSGRFLGTTCYDRSWR 347 Query: 427 LW 432 LW Sbjct: 348 LW 349 Score = 36.6 bits (83), Expect = 0.059 Identities = 19/56 (33%), Positives = 31/56 (55%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLW 180 L++G+ D T +W P + GH+ V + S DGQ +A+ S+D++ KLW Sbjct: 464 LLTGAYDNTAKIWTHP-GWSPLKTLAGHEGKVMGLDISSDGQLIATCSYDRTFKLW 518
>PRP4_ARATH (O22212) U4/U6 small nuclear ribonucleoprotein PRP4-like protein| Length = 554 Score = 82.4 bits (202), Expect = 9e-16 Identities = 46/140 (32%), Positives = 72/140 (51%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 L + S D T LW+ + GH + V F P G++L + S+DK+ +LW+ T Sbjct: 313 LATASADRTAKLWKTDGTLLQT--FEGHLDRLARVAFHPSGKYLGTTSYDKTWRLWDINT 370 Query: 193 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVD 372 G + GH VY I++ D L S DS +VWD+R + GH V++V+ Sbjct: 371 GAELLLQEGHSRSVYGIAFQQDGALAASCGLDSLARVWDLRTGRSILVFQGHIKPVFSVN 430 Query: 373 WSPDGEKVVSGGKDRALKLW 432 +SP+G + SGG+D ++W Sbjct: 431 FSPNGYHLASGGEDNQCRIW 450 Score = 75.9 bits (185), Expect = 9e-14 Identities = 40/137 (29%), Positives = 70/137 (51%), Gaps = 1/137 (0%) Frame = +1 Query: 25 SDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFV 204 S D T LW+ + + GH + V + F DG AS D ++W+ TG+ + Sbjct: 358 SYDKTWRLWDINTGAELLLQ-EGHSRSVYGIAFQQDGALAASCGLDSLARVWDLRTGRSI 416 Query: 205 TAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSP- 381 F+GH+ V+ +++S + L SG +D+ ++WD+R RK +P HA+ V V + P Sbjct: 417 LVFQGHIKPVFSVNFSPNGYHLASGGEDNQCRIWDLRMRKSLYIIPAHANLVSQVKYEPQ 476 Query: 382 DGEKVVSGGKDRALKLW 432 +G + + D + +W Sbjct: 477 EGYFLATASYDMKVNIW 493 Score = 65.9 bits (159), Expect = 9e-11 Identities = 41/131 (31%), Positives = 64/131 (48%), Gaps = 2/131 (1%) Frame = +1 Query: 46 LWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHV 225 LWE A + H++ V FSP LA+AS D++ KLW G + F GH+ Sbjct: 281 LWEMPQVTNTIAVLKDHKERATDVVFSPVDDCLATASADRTAKLWK-TDGTLLQTFEGHL 339 Query: 226 ADVYQISWSADSRLLLSGSKDSTLKVWDIR--ARKLKQDLPGHADEVYAVDWSPDGEKVV 399 + ++++ + L + S D T ++WDI A L Q+ GH+ VY + + DG Sbjct: 340 DRLARVAFHPSGKYLGTTSYDKTWRLWDINTGAELLLQE--GHSRSVYGIAFQQDGALAA 397 Query: 400 SGGKDRALKLW 432 S G D ++W Sbjct: 398 SCGLDSLARVW 408 Score = 56.6 bits (135), Expect = 6e-08 Identities = 31/99 (31%), Positives = 53/99 (53%), Gaps = 1/99 (1%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSP-DGQWLASASFDKSVKLWNGI 189 L SG +D +W+ + K + H +V+ V + P +G +LA+AS+D V +W+G Sbjct: 438 LASGGEDNQCRIWDLRMRKSLYI-IPAHANLVSQVKYEPQEGYFLATASYDMKVNIWSGR 496 Query: 190 TGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVW 306 V + GH + V + +ADS + + S D T+K+W Sbjct: 497 DFSLVKSLAGHESKVASLDITADSSCIATVSHDRTIKLW 535 Score = 43.9 bits (102), Expect = 4e-04 Identities = 31/116 (26%), Positives = 49/116 (42%), Gaps = 2/116 (1%) Frame = +1 Query: 91 GHQKVVNHVYFSPDGQWLASASFDKSVKLWN--GITGKFVTAFRGHVADVYQISWSADSR 264 G + + FS DG+ LA+ S KLW +T + + H + +S Sbjct: 253 GDDRPLTGCSFSRDGKILATCSLSGVTKLWEMPQVTNT-IAVLKDHKERATDVVFSPVDD 311 Query: 265 LLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 L + S D T K+W L Q GH D + V + P G+ + + D+ +LW Sbjct: 312 CLATASADRTAKLWKTDG-TLLQTFEGHLDRLARVAFHPSGKYLGTTSYDKTWRLW 366
>TUP1_CANAL (P56093) Transcriptional repressor TUP1| Length = 514 Score = 82.4 bits (202), Expect = 9e-16 Identities = 50/153 (32%), Positives = 80/153 (52%), Gaps = 12/153 (7%) Frame = +1 Query: 10 RLVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGI 189 RLVSGS D ++ +W+ S+ + + V V SPDG+ +A+ S D++V++W+ Sbjct: 313 RLVSGSGDRSVRIWDLRTSQC--SLTLSIEDGVTTVAVSPDGKLIAAGSLDRTVRVWDST 370 Query: 190 TGKFVTAF-------RGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLP-- 342 TG V GH VY +++S + + SGS D T+K+W + + K+ Sbjct: 371 TGFLVERLDSGNENGNGHEDSVYSVAFSNNGEQIASGSLDRTVKLWHLEGKSDKKSTCEV 430 Query: 343 ---GHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 GH D V +V +PD E ++SG KDR + W Sbjct: 431 TYIGHKDFVLSVCCTPDNEYILSGSKDRGVIFW 463 Score = 81.3 bits (199), Expect = 2e-15 Identities = 57/177 (32%), Positives = 92/177 (51%), Gaps = 10/177 (5%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 L +G++D + +W+ + + K + GH++ + + F PDG L S S D+SV++W+ T Sbjct: 272 LATGAEDKLIRIWDLSTKRIIKI-LRGHEQDIYSLDFFPDGDRLVSGSGDRSVRIWDLRT 330 Query: 193 GKFVTAFRGHVAD-VYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLP-------GH 348 + + D V ++ S D +L+ +GS D T++VWD L + L GH Sbjct: 331 SQCSLTLS--IEDGVTTVAVSPDGKLIAAGSLDRTVRVWDSTTGFLVERLDSGNENGNGH 388 Query: 349 ADEVYAVDWSPDGEKVVSGGKDRALKLWMN*ACL*YHHECY*DDK--CDDQFIEHVD 513 D VY+V +S +GE++ SG DR +KLW H E D K C+ +I H D Sbjct: 389 EDSVYSVAFSNNGEQIASGSLDRTVKLW--------HLEGKSDKKSTCEVTYIGHKD 437 Score = 81.3 bits (199), Expect = 2e-15 Identities = 38/109 (34%), Positives = 64/109 (58%) Frame = +1 Query: 106 VNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSK 285 + V FSPDG+ LA+ + DK +++W+ T + + RGH D+Y + + D L+SGS Sbjct: 260 IRSVCFSPDGKLLATGAEDKLIRIWDLSTKRIIKILRGHEQDIYSLDFFPDGDRLVSGSG 319 Query: 286 DSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 D ++++WD+R + L D V V SPDG+ + +G DR +++W Sbjct: 320 DRSVRIWDLRTSQCSLTL-SIEDGVTTVAVSPDGKLIAAGSLDRTVRVW 367 Score = 78.6 bits (192), Expect = 1e-14 Identities = 43/146 (29%), Positives = 82/146 (56%), Gaps = 17/146 (11%) Frame = +1 Query: 46 LWEPTISKQPKARMT---GHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFR 216 L+ P SK M H VV V FS DG+++A+ +K+ +++N TG+ V Sbjct: 182 LYNPAFSKDLDIDMVHSLDHSSVVCCVRFSRDGKFIATGC-NKTTQVFNVTTGELVAKLI 240 Query: 217 GHVA------------DVY--QISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHAD 354 + D+Y + +S D +LL +G++D +++WD+ +++ + L GH Sbjct: 241 DESSNENKDDNTTASGDLYIRSVCFSPDGKLLATGAEDKLIRIWDLSTKRIIKILRGHEQ 300 Query: 355 EVYAVDWSPDGEKVVSGGKDRALKLW 432 ++Y++D+ PDG+++VSG DR++++W Sbjct: 301 DIYSLDFFPDGDRLVSGSGDRSVRIW 326 Score = 57.8 bits (138), Expect = 2e-08 Identities = 45/155 (29%), Positives = 72/155 (46%), Gaps = 15/155 (9%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTIS------KQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVK 174 + +GS D T+ +W+ T GH+ V V FS +G+ +AS S D++VK Sbjct: 355 IAAGSLDRTVRVWDSTTGFLVERLDSGNENGNGHEDSVYSVAFSNNGEQIASGSLDRTVK 414 Query: 175 LWN--GITGKFVTA---FRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDL 339 LW+ G + K T + GH V + + D+ +LSGSKD + WD + L Sbjct: 415 LWHLEGKSDKKSTCEVTYIGHKDFVLSVCCTPDNEYILSGSKDRGVIFWDQASGNPLLML 474 Query: 340 PGHADEVYAVDWSPDGEKV----VSGGKDRALKLW 432 GH + V +V S + + +G D ++W Sbjct: 475 QGHRNSVISVAVSLNSKGTEGIFATGSGDCKARIW 509 Score = 48.1 bits (113), Expect = 2e-05 Identities = 31/107 (28%), Positives = 54/107 (50%), Gaps = 8/107 (7%) Frame = +1 Query: 10 RLVSGSDDFTMFLW--EPTISKQPKARMT--GHQKVVNHVYFSPDGQWLASASFDKSVKL 177 ++ SGS D T+ LW E K+ +T GH+ V V +PD +++ S S D+ V Sbjct: 403 QIASGSLDRTVKLWHLEGKSDKKSTCEVTYIGHKDFVLSVCCTPDNEYILSGSKDRGVIF 462 Query: 178 WNGITGKFVTAFRGHVADVYQISWSADSR----LLLSGSKDSTLKVW 306 W+ +G + +GH V ++ S +S+ + +GS D ++W Sbjct: 463 WDQASGNPLLMLQGHRNSVISVAVSLNSKGTEGIFATGSGDCKARIW 509
>GBLP_ORYSA (P49027) Guanine nucleotide-binding protein beta subunit-like| protein (GPB-LR) (RWD) Length = 334 Score = 82.4 bits (202), Expect = 9e-16 Identities = 54/161 (33%), Positives = 81/161 (50%), Gaps = 21/161 (13%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQ-------------PKARMTGHQKVVNHVYFSPDGQWLASA 153 +VS S D ++ +W+ T Q P R+TGH V V S DGQ+ S Sbjct: 34 IVSSSRDKSLLVWDLTNPVQNVGEGAGASEYGVPFRRLTGHSHFVQDVVLSSDGQFALSG 93 Query: 154 SFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRAR---K 324 S+D ++LW+ TG F GH DV +++S D+R ++S S+D T+K+W+ Sbjct: 94 SWDGELRLWDLSTGVTTRRFVGHDKDVLSVAFSVDNRQIVSASRDRTIKLWNTLGECKYT 153 Query: 325 LKQDL---PGHADEVYAVDWSPD--GEKVVSGGKDRALKLW 432 + DL GH V V +SP+ +VSG DR +K+W Sbjct: 154 IGGDLGGGEGHNGWVSCVRFSPNTFQPTIVSGSWDRTVKVW 194 Score = 82.0 bits (201), Expect = 1e-15 Identities = 55/147 (37%), Positives = 78/147 (53%), Gaps = 8/147 (5%) Frame = +1 Query: 16 VSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGI-- 189 +SGS D + LW+ + + R GH K V V FS D + + SAS D+++KLWN + Sbjct: 91 LSGSWDGELRLWDLSTGVTTR-RFVGHDKDVLSVAFSVDNRQIVSASRDRTIKLWNTLGE 149 Query: 190 ----TGKFVTAFRGHVADVYQISWSADS--RLLLSGSKDSTLKVWDIRARKLKQDLPGHA 351 G + GH V + +S ++ ++SGS D T+KVW++ KL+ +L GH Sbjct: 150 CKYTIGGDLGGGEGHNGWVSCVRFSPNTFQPTIVSGSWDRTVKVWNLTNCKLRCNLEGHG 209 Query: 352 DEVYAVDWSPDGEKVVSGGKDRALKLW 432 V AV SPDG SGGKD LW Sbjct: 210 GYVNAVAVSPDGSLCASGGKDGVTLLW 236 Score = 60.1 bits (144), Expect = 5e-09 Identities = 42/147 (28%), Positives = 77/147 (52%), Gaps = 7/147 (4%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 +VSGS D T+ +W T K + + GH VN V SPDG AS D LW+ Sbjct: 182 IVSGSWDRTVKVWNLTNCKL-RCNLEGHGGYVNAVAVSPDGSLCASGGKDGVTLLWDLAE 240 Query: 193 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDL----PGHADEV 360 GK + + + ++ + +S + L + ++DS +K+WD+ ++ + QDL P +++ Sbjct: 241 GKRLYSLDAG-SIIHSLCFSPNRYWLCAATQDS-IKIWDLESKHIVQDLKPEIPVSKNQM 298 Query: 361 Y---AVDWSPDGEKVVSGGKDRALKLW 432 +++WS DG + +G D ++++ Sbjct: 299 LYCTSLNWSADGSTLYAGYTDGTIRIY 325 Score = 51.2 bits (121), Expect = 2e-06 Identities = 43/149 (28%), Positives = 69/149 (46%), Gaps = 8/149 (5%) Frame = +1 Query: 10 RLVSGSDDFTMFLWEP------TISKQPKARMTGHQKVVNHVYFSPDG--QWLASASFDK 165 ++VS S D T+ LW TI GH V+ V FSP+ + S S+D+ Sbjct: 131 QIVSASRDRTIKLWNTLGECKYTIGGDLGGG-EGHNGWVSCVRFSPNTFQPTIVSGSWDR 189 Query: 166 SVKLWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPG 345 +VK+WN K GH V ++ S D L SG KD +WD+ K L Sbjct: 190 TVKVWNLTNCKLRCNLEGHGGYVNAVAVSPDGSLCASGGKDGVTLLWDLAEGKRLYSLDA 249 Query: 346 HADEVYAVDWSPDGEKVVSGGKDRALKLW 432 ++++ +SP+ + + +D ++K+W Sbjct: 250 -GSIIHSLCFSPNRYWLCAATQD-SIKIW 276 Score = 42.0 bits (97), Expect = 0.001 Identities = 27/106 (25%), Positives = 51/106 (48%), Gaps = 8/106 (7%) Frame = +1 Query: 19 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 198 SG D LW+ K+ + G +++ + FSP+ WL +A+ D S+K+W+ + K Sbjct: 226 SGGKDGVTLLWDLAEGKRLYSLDAG--SIIHSLCFSPNRYWLCAATQD-SIKIWD-LESK 281 Query: 199 FVT--------AFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDI 312 + + + ++WSAD L +G D T++++ I Sbjct: 282 HIVQDLKPEIPVSKNQMLYCTSLNWSADGSTLYAGYTDGTIRIYKI 327 Score = 33.5 bits (75), Expect = 0.50 Identities = 28/87 (32%), Positives = 40/87 (45%), Gaps = 15/87 (17%) Frame = +1 Query: 217 GHVADVYQISWSAD-SRLLLSGSKDSTLKVWDIR---------ARKLKQDLP-----GHA 351 GH V I+ D S ++S S+D +L VWD+ A + +P GH+ Sbjct: 16 GHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPVQNVGEGAGASEYGVPFRRLTGHS 75 Query: 352 DEVYAVDWSPDGEKVVSGGKDRALKLW 432 V V S DG+ +SG D L+LW Sbjct: 76 HFVQDVVLSSDGQFALSGSWDGELRLW 102
>KTNB1_ARATH (Q8H0T9) Katanin p80 WD40-containing subunit B1 homolog 1| Length = 837 Score = 82.4 bits (202), Expect = 9e-16 Identities = 41/140 (29%), Positives = 77/140 (55%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 + +G+ T+ LW+ +K + +TGH+ V F P G++ AS S D ++K+W+ Sbjct: 74 VAAGAASGTIKLWDLEEAKIVRT-LTGHRSNCISVDFHPFGEFFASGSLDTNLKIWDIRK 132 Query: 193 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVD 372 + ++GH V + ++ D R ++SG +D+ +KVWD+ A KL + H ++ ++D Sbjct: 133 KGCIHTYKGHTRGVNVLRFTPDGRWVVSGGEDNIVKVWDLTAGKLLTEFKSHEGQIQSLD 192 Query: 373 WSPDGEKVVSGGKDRALKLW 432 + P + +G DR +K W Sbjct: 193 FHPHEFLLATGSADRTVKFW 212 Score = 79.0 bits (193), Expect = 1e-14 Identities = 46/142 (32%), Positives = 72/142 (50%), Gaps = 2/142 (1%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMT--GHQKVVNHVYFSPDGQWLASASFDKSVKLWNG 186 LV+G +D + LW I K P A ++ GH ++ V F +A+ + ++KLW+ Sbjct: 32 LVTGGEDHKVNLW--AIGK-PNAILSLYGHSSGIDSVTFDASEVLVAAGAASGTIKLWDL 88 Query: 187 ITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYA 366 K V GH ++ + + SGS D+ LK+WDIR + GH V Sbjct: 89 EEAKIVRTLTGHRSNCISVDFHPFGEFFASGSLDTNLKIWDIRKKGCIHTYKGHTRGVNV 148 Query: 367 VDWSPDGEKVVSGGKDRALKLW 432 + ++PDG VVSGG+D +K+W Sbjct: 149 LRFTPDGRWVVSGGEDNIVKVW 170 Score = 74.7 bits (182), Expect = 2e-13 Identities = 41/129 (31%), Positives = 65/129 (50%) Frame = +1 Query: 19 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 198 SGS D + +W+ K GH + VN + F+PDG+W+ S D VK+W+ GK Sbjct: 118 SGSLDTNLKIWDIR-KKGCIHTYKGHTRGVNVLRFTPDGRWVVSGGEDNIVKVWDLTAGK 176 Query: 199 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWS 378 +T F+ H + + + LL +GS D T+K WD+ +L V + ++ Sbjct: 177 LLTEFKSHEGQIQSLDFHPHEFLLATGSADRTVKFWDLETFELIGSGGPETAGVRCLSFN 236 Query: 379 PDGEKVVSG 405 PDG+ V+ G Sbjct: 237 PDGKTVLCG 245 Score = 40.8 bits (94), Expect = 0.003 Identities = 27/98 (27%), Positives = 51/98 (52%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 +VSG +D + +W+ T K H+ + + F P LA+ S D++VK W+ T Sbjct: 158 VVSGGEDNIVKVWDLTAGKL-LTEFKSHEGQIQSLDFHPHEFLLATGSADRTVKFWDLET 216 Query: 193 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVW 306 + + + A V +S++ D + +L G ++S LK++ Sbjct: 217 FELIGSGGPETAGVRCLSFNPDGKTVLCGLQES-LKIF 253 Score = 35.4 bits (80), Expect = 0.13 Identities = 24/100 (24%), Positives = 36/100 (36%), Gaps = 42/100 (42%) Frame = +1 Query: 259 SRLLLSGSKD------------------------------------------STLKVWDI 312 SR+L++G +D T+K+WD+ Sbjct: 29 SRVLVTGGEDHKVNLWAIGKPNAILSLYGHSSGIDSVTFDASEVLVAAGAASGTIKLWDL 88 Query: 313 RARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 K+ + L GH +VD+ P GE SG D LK+W Sbjct: 89 EEAKIVRTLTGHRSNCISVDFHPFGEFFASGSLDTNLKIW 128
>SPG16_HUMAN (Q8N0X2) Sperm-associated antigen 16 protein (PF20 protein homolog)| Length = 631 Score = 81.3 bits (199), Expect = 2e-15 Identities = 36/114 (31%), Positives = 61/114 (53%) Frame = +1 Query: 91 GHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLL 270 GH ++ F P G LA++S D +VKLW+ TG + F GH V+ +W + + Sbjct: 392 GHTDWLSDCCFHPSGDKLATSSGDTTVKLWDLCTGDCILTFEGHSRAVWSCTWHSCGNFV 451 Query: 271 LSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 S S D T K+WD+ + + + L GH D V ++++ P +++ D+ L +W Sbjct: 452 ASSSLDKTSKIWDVNSERCRCTLYGHTDSVNSIEFFPFSNTLLTSSADKTLSIW 505 Score = 65.5 bits (158), Expect = 1e-10 Identities = 41/141 (29%), Positives = 63/141 (44%) Frame = +1 Query: 10 RLVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGI 189 +L + S D T+ LW+ + GH + V + G ++AS+S DK+ K+W+ Sbjct: 408 KLATSSGDTTVKLWD-LCTGDCILTFEGHSRAVWSCTWHSCGNFVASSSLDKTSKIWDVN 466 Query: 190 TGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAV 369 + + GH V I + S LL+ S D TL +WD R +Q L GH + Sbjct: 467 SERCRCTLYGHTDSVNSIEFFPFSNTLLTSSADKTLSIWDARTGICEQSLYGHMHSINDA 526 Query: 370 DWSPDGEKVVSGGKDRALKLW 432 + P G + S KLW Sbjct: 527 IFDPRGHMIASCDACGVTKLW 547 Score = 55.8 bits (133), Expect = 9e-08 Identities = 34/140 (24%), Positives = 69/140 (49%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 L++ S D T+ +W+ ++ + GH +N F P G +AS KLW+ Sbjct: 493 LLTSSADKTLSIWDARTGICEQS-LYGHMHSINDAIFDPRGHMIASCDACGVTKLWDFRK 551 Query: 193 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVD 372 + + + ++++ + R+L S + + + D+++ ++ + L GH +E + V Sbjct: 552 LLPIVSIDIGPSPGNEVNFDSSGRVLAQASGNGVIHLLDLKSGEIHK-LMGHENEAHTVV 610 Query: 373 WSPDGEKVVSGGKDRALKLW 432 +S DGE + SGG D ++ W Sbjct: 611 FSHDGEILFSGGSDGTVRTW 630 Score = 29.3 bits (64), Expect = 9.5 Identities = 12/34 (35%), Positives = 20/34 (58%) Frame = +1 Query: 82 RMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWN 183 ++ GH+ + V FS DG+ L S D +V+ W+ Sbjct: 598 KLMGHENEAHTVVFSHDGEILFSGGSDGTVRTWS 631
>SEL10_CAEEL (Q93794) F-box/WD-repeat protein sel-10 (Suppressor/enhancer of| lin-12) (Sel-10 protein) Length = 587 Score = 81.3 bits (199), Expect = 2e-15 Identities = 49/141 (34%), Positives = 80/141 (56%), Gaps = 1/141 (0%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISK-QPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGI 189 LV+GSDD T+ +W I K + + GH V S G+++ S S D++VK+W+ + Sbjct: 269 LVTGSDDNTLKVW--CIDKGEVMYTLVGHTGGVWTSQISQCGRYIVSGSTDRTVKVWSTV 326 Query: 190 TGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAV 369 G + +GH + V ++ + +L++GS+D+TL+VWD+ + + L GH V V Sbjct: 327 DGSLLHTLQGHTSTVRCMAMAGS--ILVTGSRDTTLRVWDVESGRHLATLHGHHAAVRCV 384 Query: 370 DWSPDGEKVVSGGKDRALKLW 432 + DG VVSGG D +K+W Sbjct: 385 QF--DGTTVVSGGYDFTVKIW 403 Score = 67.8 bits (164), Expect = 2e-11 Identities = 43/143 (30%), Positives = 72/143 (50%), Gaps = 3/143 (2%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 LV+GS D T+ +W+ S + A + GH V V F DG + S +D +VK+WN T Sbjct: 351 LVTGSRDTTLRVWDVE-SGRHLATLHGHHAAVRCVQF--DGTTVVSGGYDFTVKIWNAHT 407 Query: 193 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDI---RARKLKQDLPGHADEVY 363 G+ + GH VY + + ++ ++ SGS D++++VWD ++ L GH Sbjct: 408 GRCIRTLTGHNNRVYSLLFESERSIVCSGSLDTSIRVWDFTRPEGQECVALLQGHTSLTS 467 Query: 364 AVDWSPDGEKVVSGGKDRALKLW 432 + G +VS D +++W Sbjct: 468 GMQLR--GNILVSCNADSHVRVW 488 Score = 52.4 bits (124), Expect = 1e-06 Identities = 33/91 (36%), Positives = 43/91 (47%) Frame = +1 Query: 160 DKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDL 339 DK K WN RGH V D +L++GS D+TLKVW I ++ L Sbjct: 234 DKIEKNWNANPIMGSAVLRGHEDHVITCMQIHDD-VLVTGSDDNTLKVWCIDKGEVMYTL 292 Query: 340 PGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 GH V+ S G +VSG DR +K+W Sbjct: 293 VGHTGGVWTSQISQCGRYIVSGSTDRTVKVW 323
>EBI_DROME (Q95RJ9) F-box-like/WD repeat protein ebi| Length = 700 Score = 80.1 bits (196), Expect = 5e-15 Identities = 41/130 (31%), Positives = 66/130 (50%), Gaps = 9/130 (6%) Frame = +1 Query: 70 QPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISW 249 +P GH VN + + P GQ LAS S D ++K+W+ + + H ++Y I W Sbjct: 525 EPIKTFKGHTNEVNAIKWCPQGQLLASCSDDMTLKIWSMNRDRCCHDLQAHSKEIYTIKW 584 Query: 250 SAD---------SRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVS 402 S + +L S S DST+++WD+ L H + VY+V +SPDG+ + S Sbjct: 585 SPTGPGTNNPNTNLILASASFDSTVRLWDVERGSCIHTLTKHTEPVYSVAFSPDGKHLAS 644 Query: 403 GGKDRALKLW 432 G D+ + +W Sbjct: 645 GSFDKCVHIW 654 Score = 65.1 bits (157), Expect = 2e-10 Identities = 42/143 (29%), Positives = 65/143 (45%), Gaps = 9/143 (6%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQW---------LASASFDK 165 L S SDD T+ +W + + H K + + +SP G LASASFD Sbjct: 549 LASCSDDMTLKIWSMNRDRCCHD-LQAHSKEIYTIKWSPTGPGTNNPNTNLILASASFDS 607 Query: 166 SVKLWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPG 345 +V+LW+ G + H VY +++S D + L SGS D + +W + +L G Sbjct: 608 TVRLWDVERGSCIHTLTKHTEPVYSVAFSPDGKHLASGSFDKCVHIWSTQTGQLVHSYKG 667 Query: 346 HADEVYAVDWSPDGEKVVSGGKD 414 ++ V W+ G KV + D Sbjct: 668 -TGGIFEVCWNSKGTKVGASASD 689 Score = 63.2 bits (152), Expect = 6e-10 Identities = 40/149 (26%), Positives = 65/149 (43%), Gaps = 9/149 (6%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 ++S D T +W+ + Q + H V + + Q AS S D+ + + Sbjct: 466 ILSAGVDKTTIIWDASTG-QCTQQFAFHSAPALDVDWQTN-QAFASCSTDQRIHVCRLGV 523 Query: 193 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVD 372 + + F+GH +V I W +LL S S D TLK+W + + DL H+ E+Y + Sbjct: 524 NEPIKTFKGHTNEVNAIKWCPQGQLLASCSDDMTLKIWSMNRDRCCHDLQAHSKEIYTIK 583 Query: 373 WSPDGEK---------VVSGGKDRALKLW 432 WSP G + S D ++LW Sbjct: 584 WSPTGPGTNNPNTNLILASASFDSTVRLW 612 Score = 59.3 bits (142), Expect = 9e-09 Identities = 35/140 (25%), Positives = 64/140 (45%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 L +GS D +W+ + + + H+ + + ++ G ++ SA DK+ +W+ T Sbjct: 425 LATGSYDGYARIWKT--DGRLASTLGQHKGPIFALKWNKCGNYILSAGVDKTTIIWDAST 482 Query: 193 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVD 372 G+ F H A + W ++ S S D + V + + + GH +EV A+ Sbjct: 483 GQCTQQFAFHSAPALDVDWQT-NQAFASCSTDQRIHVCRLGVNEPIKTFKGHTNEVNAIK 541 Query: 373 WSPDGEKVVSGGKDRALKLW 432 W P G+ + S D LK+W Sbjct: 542 WCPQGQLLASCSDDMTLKIW 561 Score = 53.1 bits (126), Expect = 6e-07 Identities = 36/135 (26%), Positives = 59/135 (43%), Gaps = 14/135 (10%) Frame = +1 Query: 70 QPKAR-MTGHQKVVNHVYFSPDGQWLASASFDKSVKLW---NGITGKFVTAFRGHV---- 225 + KAR + GH+ V ++P LAS S D + ++W + T R + Sbjct: 345 ESKARVLRGHESEVFICAWNPSRDLLASGSGDSTARIWDMSDANTNSNQLVLRHCIQKGG 404 Query: 226 ------ADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDG 387 DV + W+ D LL +GS D ++W R L L H ++A+ W+ G Sbjct: 405 AEVPSNKDVTSLDWNCDGSLLATGSYDGYARIWKTDGR-LASTLGQHKGPIFALKWNKCG 463 Query: 388 EKVVSGGKDRALKLW 432 ++S G D+ +W Sbjct: 464 NYILSAGVDKTTIIW 478 Score = 33.1 bits (74), Expect = 0.66 Identities = 14/49 (28%), Positives = 26/49 (53%) Frame = +1 Query: 286 DSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 D +++ + +AR L+ GH EV+ W+P + + SG D ++W Sbjct: 338 DENIEIPESKARVLR----GHESEVFICAWNPSRDLLASGSGDSTARIW 382
>GBB1_CAEEL (P17343) Guanine nucleotide-binding protein beta subunit 1| Length = 340 Score = 79.7 bits (195), Expect = 6e-15 Identities = 42/116 (36%), Positives = 63/116 (54%) Frame = +1 Query: 85 MTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSR 264 + GH ++ F D Q + ++S D + LW+ TG+ TAF GH DV +S S D R Sbjct: 139 LPGHTGYLSCCRFLDDNQ-IVTSSGDMTCALWDIETGQQCTAFTGHTGDVMSLSLSPDFR 197 Query: 265 LLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 +SG+ D++ K+WDIR KQ PGH ++ AV + P G +G D +L+ Sbjct: 198 TFISGACDASAKLWDIRDGMCKQTFPGHESDINAVAFFPSGNAFATGSDDATCRLF 253 Score = 62.0 bits (149), Expect = 1e-09 Identities = 42/146 (28%), Positives = 71/146 (48%), Gaps = 5/146 (3%) Frame = +1 Query: 10 RLVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGI 189 ++V+ S D T LW+ +Q A TGH V + SPD + S + D S KLW+ Sbjct: 156 QIVTSSGDMTCALWDIETGQQCTA-FTGHTGDVMSLSLSPDFRTFISGACDASAKLWDIR 214 Query: 190 TGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADE---- 357 G F GH +D+ +++ +GS D+T +++DIRA Q+L ++ + Sbjct: 215 DGMCKQTFPGHESDINAVAFFPSGNAFATGSDDATCRLFDIRA---DQELAMYSHDNIIC 271 Query: 358 -VYAVDWSPDGEKVVSGGKDRALKLW 432 + +V +S G + +G D +W Sbjct: 272 GITSVAFSKSGRLLFAGYDDFNCNVW 297 Score = 59.7 bits (143), Expect = 7e-09 Identities = 41/142 (28%), Positives = 65/142 (45%), Gaps = 3/142 (2%) Frame = +1 Query: 16 VSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITG 195 +SG+ D + LW+ K GH+ +N V F P G A+ S D + +L++ I Sbjct: 200 ISGACDASAKLWDIR-DGMCKQTFPGHESDINAVAFFPSGNAFATGSDDATCRLFD-IRA 257 Query: 196 KFVTAFRGH---VADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYA 366 A H + + +++S RLL +G D VWD ++ L GH + V Sbjct: 258 DQELAMYSHDNIICGITSVAFSKSGRLLFAGYDDFNCNVWDSMRQERAGVLAGHDNRVSC 317 Query: 367 VDWSPDGEKVVSGGKDRALKLW 432 + + DG V +G D LK+W Sbjct: 318 LGVTEDGMAVCTGSWDSFLKIW 339 Score = 52.4 bits (124), Expect = 1e-06 Identities = 25/73 (34%), Positives = 38/73 (52%) Frame = +1 Query: 214 RGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEK 393 RGH+A +Y + W++DSR L+S S+D L VWD +P + V ++P G Sbjct: 52 RGHLAKIYAMHWASDSRNLVSASQDGKLIVWDSYTTNKVHAIPLRSSWVMTCAYAPSGSF 111 Query: 394 VVSGGKDRALKLW 432 V GG D ++ Sbjct: 112 VACGGLDNICSIY 124 Score = 42.4 bits (98), Expect = 0.001 Identities = 28/128 (21%), Positives = 57/128 (44%), Gaps = 4/128 (3%) Frame = +1 Query: 61 ISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQ 240 I + + + GH + ++++ D + L SAS D + +W+ T V A + V Sbjct: 43 IQMRTRRTLRGHLAKIYAMHWASDSRNLVSASQDGKLIVWDSYTTNKVHAIPLRSSWVMT 102 Query: 241 ISWSADSRLLLSGSKDSTLKVWDIRAR----KLKQDLPGHADEVYAVDWSPDGEKVVSGG 408 +++ + G D+ ++ ++ R ++ ++LPGH + + D + V S G Sbjct: 103 CAYAPSGSFVACGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFLDDNQIVTSSG 162 Query: 409 KDRALKLW 432 D LW Sbjct: 163 -DMTCALW 169 Score = 39.3 bits (90), Expect = 0.009 Identities = 27/100 (27%), Positives = 46/100 (46%), Gaps = 3/100 (3%) Frame = +1 Query: 19 SGSDDFTMFLWEPTISKQPKARMTGHQKVV---NHVYFSPDGQWLASASFDKSVKLWNGI 189 +GSDD T L++ I + M H ++ V FS G+ L + D + +W+ + Sbjct: 243 TGSDDATCRLFD--IRADQELAMYSHDNIICGITSVAFSKSGRLLFAGYDDFNCNVWDSM 300 Query: 190 TGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWD 309 + GH V + + D + +GS DS LK+W+ Sbjct: 301 RQERAGVLAGHDNRVSCLGVTEDGMAVCTGSWDSFLKIWN 340
>GBB1_CAEBR (Q61ZF6) Guanine nucleotide-binding protein beta subunit 1| Length = 340 Score = 79.7 bits (195), Expect = 6e-15 Identities = 42/116 (36%), Positives = 63/116 (54%) Frame = +1 Query: 85 MTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSR 264 + GH ++ F D Q + ++S D + LW+ TG+ TAF GH DV +S S D R Sbjct: 139 LPGHTGYLSCCRFLDDNQ-IVTSSGDMTCALWDIETGQQCTAFTGHTGDVMSLSLSPDFR 197 Query: 265 LLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 +SG+ D++ K+WDIR KQ PGH ++ AV + P G +G D +L+ Sbjct: 198 TFISGACDASAKLWDIRDGMCKQTFPGHESDINAVAFFPSGNAFATGSDDATCRLF 253 Score = 62.0 bits (149), Expect = 1e-09 Identities = 42/146 (28%), Positives = 71/146 (48%), Gaps = 5/146 (3%) Frame = +1 Query: 10 RLVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGI 189 ++V+ S D T LW+ +Q A TGH V + SPD + S + D S KLW+ Sbjct: 156 QIVTSSGDMTCALWDIETGQQCTA-FTGHTGDVMSLSLSPDFRTFISGACDASAKLWDIR 214 Query: 190 TGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADE---- 357 G F GH +D+ +++ +GS D+T +++DIRA Q+L ++ + Sbjct: 215 DGMCKQTFPGHESDINAVAFFPSGNAFATGSDDATCRLFDIRA---DQELAMYSHDNIIC 271 Query: 358 -VYAVDWSPDGEKVVSGGKDRALKLW 432 + +V +S G + +G D +W Sbjct: 272 GITSVAFSKSGRLLFAGYDDFNCNVW 297 Score = 59.7 bits (143), Expect = 7e-09 Identities = 41/142 (28%), Positives = 65/142 (45%), Gaps = 3/142 (2%) Frame = +1 Query: 16 VSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITG 195 +SG+ D + LW+ K GH+ +N V F P G A+ S D + +L++ I Sbjct: 200 ISGACDASAKLWDIR-DGMCKQTFPGHESDINAVAFFPSGNAFATGSDDATCRLFD-IRA 257 Query: 196 KFVTAFRGH---VADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYA 366 A H + + +++S RLL +G D VWD ++ L GH + V Sbjct: 258 DQELAMYSHDNIICGITSVAFSKSGRLLFAGYDDFNCNVWDSMRQERAGVLAGHDNRVSC 317 Query: 367 VDWSPDGEKVVSGGKDRALKLW 432 + + DG V +G D LK+W Sbjct: 318 LGVTEDGMAVCTGSWDSFLKIW 339 Score = 52.4 bits (124), Expect = 1e-06 Identities = 25/73 (34%), Positives = 38/73 (52%) Frame = +1 Query: 214 RGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEK 393 RGH+A +Y + W++DSR L+S S+D L VWD +P + V ++P G Sbjct: 52 RGHLAKIYAMHWASDSRNLVSASQDGKLIVWDSYTTNKVHAIPLRSSWVMTCAYAPSGSF 111 Query: 394 VVSGGKDRALKLW 432 V GG D ++ Sbjct: 112 VACGGLDNICSIY 124 Score = 42.4 bits (98), Expect = 0.001 Identities = 28/128 (21%), Positives = 57/128 (44%), Gaps = 4/128 (3%) Frame = +1 Query: 61 ISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQ 240 I + + + GH + ++++ D + L SAS D + +W+ T V A + V Sbjct: 43 IQMRTRRTLRGHLAKIYAMHWASDSRNLVSASQDGKLIVWDSYTTNKVHAIPLRSSWVMT 102 Query: 241 ISWSADSRLLLSGSKDSTLKVWDIRAR----KLKQDLPGHADEVYAVDWSPDGEKVVSGG 408 +++ + G D+ ++ ++ R ++ ++LPGH + + D + V S G Sbjct: 103 CAYAPSGSFVACGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFLDDNQIVTSSG 162 Query: 409 KDRALKLW 432 D LW Sbjct: 163 -DMTCALW 169 Score = 39.3 bits (90), Expect = 0.009 Identities = 27/100 (27%), Positives = 46/100 (46%), Gaps = 3/100 (3%) Frame = +1 Query: 19 SGSDDFTMFLWEPTISKQPKARMTGHQKVV---NHVYFSPDGQWLASASFDKSVKLWNGI 189 +GSDD T L++ I + M H ++ V FS G+ L + D + +W+ + Sbjct: 243 TGSDDATCRLFD--IRADQELAMYSHDNIICGITSVAFSKSGRLLFAGYDDFNCNVWDSM 300 Query: 190 TGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWD 309 + GH V + + D + +GS DS LK+W+ Sbjct: 301 RQERAGVLAGHDNRVSCLGVTEDGMAVCTGSWDSFLKIWN 340
>YH92_CAEEL (Q23256) Hypothetical WD-repeat protein ZC302.2| Length = 501 Score = 79.7 bits (195), Expect = 6e-15 Identities = 33/116 (28%), Positives = 66/116 (56%) Frame = +1 Query: 85 MTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSR 264 ++GH K V+ + FS G++L + S DK +K+WN + ++ H + SWS++S+ Sbjct: 209 ISGHTKSVSVIKFSYCGKYLGTGSADKQIKVWNTVDMTYLQTLASHQLGINDFSWSSNSQ 268 Query: 265 LLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 + S S D+T+K++D+ + + + GH + V+ ++P + S G D +++W Sbjct: 269 FIASASDDTTVKIFDVISGACLRTMRGHTNYVFCCSFNPQSSLIASAGFDETVRVW 324 Score = 79.0 bits (193), Expect = 1e-14 Identities = 40/140 (28%), Positives = 76/140 (54%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 L +GS D + +W T+ + HQ +N +S + Q++ASAS D +VK+++ I+ Sbjct: 228 LGTGSADKQIKVWN-TVDMTYLQTLASHQLGINDFSWSSNSQFIASASDDTTVKIFDVIS 286 Query: 193 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVD 372 G + RGH V+ S++ S L+ S D T++VWD + + +P H+D + ++ Sbjct: 287 GACLRTMRGHTNYVFCCSFNPQSSLIASAGFDETVRVWDFKTGLCVKCIPAHSDPITSIS 346 Query: 373 WSPDGEKVVSGGKDRALKLW 432 ++ DG + + D +++W Sbjct: 347 YNHDGNTMATSSYDGCIRVW 366 Score = 70.9 bits (172), Expect = 3e-12 Identities = 45/142 (31%), Positives = 73/142 (51%), Gaps = 2/142 (1%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 + S SDD T+ +++ IS M GH V F+P +ASA FD++V++W+ T Sbjct: 270 IASASDDTTVKIFD-VISGACLRTMRGHTNYVFCCSFNPQSSLIASAGFDETVRVWDFKT 328 Query: 193 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDL--PGHADEVYA 366 G V H + IS++ D + + S D ++VWD + + L HA + Sbjct: 329 GLCVKCIPAHSDPITSISYNHDGNTMATSSYDGCIRVWDAASGSCLKTLVDTDHAPVTF- 387 Query: 367 VDWSPDGEKVVSGGKDRALKLW 432 V +SP+G+ ++S D +LKLW Sbjct: 388 VCFSPNGKYLLSAQLDSSLKLW 409 Score = 70.5 bits (171), Expect = 4e-12 Identities = 43/145 (29%), Positives = 70/145 (48%), Gaps = 5/145 (3%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 + + S D + +W+ K + V V FSP+G++L SA D S+KLW+ Sbjct: 354 MATSSYDGCIRVWDAASGSCLKTLVDTDHAPVTFVCFSPNGKYLLSAQLDSSLKLWDPKK 413 Query: 193 GKFVTAFRGHVADVYQISWSADSRL---LLSGSKDSTLKVWDIRARKLKQDLPGHADEVY 363 K + + GH Y + + L ++SGS+D + VW I+ +++ Q L GH V Sbjct: 414 AKPLKYYNGHKNKKYCLFANMSVPLGKHIISGSEDGRILVWSIQTKQIVQILEGHTTPVL 473 Query: 364 AVDWSPDGEKVVSGG--KDRALKLW 432 A D P + SGG D +++W Sbjct: 474 ATDSHPTLNIIASGGLEPDNVIRIW 498 Score = 39.3 bits (90), Expect = 0.009 Identities = 28/99 (28%), Positives = 43/99 (43%), Gaps = 9/99 (9%) Frame = +1 Query: 181 NGITGK-------FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDL 339 +GIT K V GH V I +S + L +GS D +KVW+ Q L Sbjct: 192 SGITKKPENGEFSLVKTISGHTKSVSVIKFSYCGKYLGTGSADKQIKVWNTVDMTYLQTL 251 Query: 340 PGHADEVYAVDWSPDGEKVVSGGKDRALKLW--MN*ACL 450 H + WS + + + S D +K++ ++ ACL Sbjct: 252 ASHQLGINDFSWSSNSQFIASASDDTTVKIFDVISGACL 290
>LIS1_DROME (Q7KNS3) Lissencephaly-1 homolog (Lissencephaly1) (Dlis1) (DLis-1)| Length = 411 Score = 79.7 bits (195), Expect = 6e-15 Identities = 38/120 (31%), Positives = 70/120 (58%), Gaps = 1/120 (0%) Frame = +1 Query: 76 KARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSA 255 K +TGH+ + V F P + SAS D ++++W+ TG++ + +GH V +++ A Sbjct: 101 KFSLTGHRASITRVIFHPIFALMVSASEDATIRIWDFETGEYERSLKGHTDSVQDVAFDA 160 Query: 256 DSRLLLSGSKDSTLKVWDI-RARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 +LL S S D ++K+WD ++ + + + GH V +V + P G+ V+S +DR +K+W Sbjct: 161 QGKLLASCSADLSIKLWDFQQSYECIKTMHGHDHNVSSVAFVPAGDYVLSASRDRTIKMW 220 Score = 73.6 bits (179), Expect = 4e-13 Identities = 43/160 (26%), Positives = 73/160 (45%), Gaps = 20/160 (12%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 L S S D ++ LW+ S + M GH V+ V F P G ++ SAS D+++K+W T Sbjct: 165 LASCSADLSIKLWDFQQSYECIKTMHGHDHNVSSVAFVPAGDYVLSASRDRTIKMWEVAT 224 Query: 193 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVD 372 G V + GH V + + + + S D T++VW ++ K +L H V + Sbjct: 225 GYCVKTYTGHREWVRMVRVHIEGSIFATCSNDQTIRVWLTNSKDCKVELRDHEHTVECIA 284 Query: 373 WSPD--------------------GEKVVSGGKDRALKLW 432 W+P+ G + SG +D+ +++W Sbjct: 285 WAPEAAASAINEAAGADNKKGHHQGPFLASGSRDKTIRIW 324 Score = 67.4 bits (163), Expect = 3e-11 Identities = 41/156 (26%), Positives = 75/156 (48%), Gaps = 20/156 (12%) Frame = +1 Query: 25 SDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPD--------------------GQWL 144 S+D T+ +W T SK K + H+ V + ++P+ G +L Sbjct: 254 SNDQTIRVWL-TNSKDCKVELRDHEHTVECIAWAPEAAASAINEAAGADNKKGHHQGPFL 312 Query: 145 ASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARK 324 AS S DK++++W+ G + GH V +++ + L+S S D T++VWD+R ++ Sbjct: 313 ASGSRDKTIRIWDVSVGLCLLTLSGHDNWVRGLAFHPGGKYLVSASDDKTIRVWDLRNKR 372 Query: 325 LKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 + L H ++D+ V+SG D+ +K+W Sbjct: 373 CMKTLYAHQHFCTSIDFHKAHPYVISGSVDQTVKVW 408 Score = 65.9 bits (159), Expect = 9e-11 Identities = 38/142 (26%), Positives = 71/142 (50%), Gaps = 1/142 (0%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 +VS S+D T+ +W+ + ++ + GH V V F G+ LAS S D S+KLW+ Sbjct: 123 MVSASEDATIRIWDFETGEYERS-LKGHTDSVQDVAFDAQGKLLASCSADLSIKLWDFQQ 181 Query: 193 G-KFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAV 369 + + GH +V +++ +LS S+D T+K+W++ + GH + V V Sbjct: 182 SYECIKTMHGHDHNVSSVAFVPAGDYVLSASRDRTIKMWEVATGYCVKTYTGHREWVRMV 241 Query: 370 DWSPDGEKVVSGGKDRALKLWM 435 +G + D+ +++W+ Sbjct: 242 RVHIEGSIFATCSNDQTIRVWL 263 Score = 55.8 bits (133), Expect = 9e-08 Identities = 31/101 (30%), Positives = 53/101 (52%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 L SGS D T+ +W+ ++ ++GH V + F P G++L SAS DK++++W+ Sbjct: 312 LASGSRDKTIRIWDVSVGLC-LLTLSGHDNWVRGLAFHPGGKYLVSASDDKTIRVWDLRN 370 Query: 193 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIR 315 + + H I + ++SGS D T+KVW+ R Sbjct: 371 KRCMKTLYAHQHFCTSIDFHKAHPYVISGSVDQTVKVWECR 411
>PLRG1_RAT (Q9WUC8) Pleiotropic regulator 1| Length = 514 Score = 79.7 bits (195), Expect = 6e-15 Identities = 43/139 (30%), Positives = 70/139 (50%) Frame = +1 Query: 16 VSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITG 195 V+GS D T+ +W+ K K +TGH V V S +L S DK VK W+ Sbjct: 220 VTGSADRTIKIWDLASGKL-KLSLTGHISTVRGVIVSTRSPYLFSCGEDKQVKCWDLEYN 278 Query: 196 KFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDW 375 K + + GH++ VY + +L++ S+DST ++WD+R + L GH + V V Sbjct: 279 KVIRHYHGHLSAVYGLDLHPTIDVLVTCSRDSTARIWDVRTKASVHTLSGHTNAVATVRC 338 Query: 376 SPDGEKVVSGGKDRALKLW 432 ++++G D ++LW Sbjct: 339 QAAEPQIITGSHDTTIRLW 357 Score = 71.6 bits (174), Expect = 2e-12 Identities = 33/116 (28%), Positives = 59/116 (50%) Frame = +1 Query: 85 MTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSR 264 ++GH V + P QW + S D+++K+W+ +GK + GH++ V + S S Sbjct: 200 ISGHLGWVRCIAVEPGNQWFVTGSADRTIKIWDLASGKLKLSLTGHISTVRGVIVSTRSP 259 Query: 265 LLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 L S +D +K WD+ K+ + GH VY +D P + +V+ +D ++W Sbjct: 260 YLFSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYGLDLHPTIDVLVTCSRDSTARIW 315 Score = 54.3 bits (129), Expect = 3e-07 Identities = 39/152 (25%), Positives = 76/152 (50%), Gaps = 8/152 (5%) Frame = +1 Query: 1 APXRLVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLW 180 A ++++GS D T+ LW+ ++ + + +T H+K V V P AS S D ++K W Sbjct: 341 AEPQIITGSHDTTIRLWD-LVAGKTRVTLTNHKKSVRAVVLHPLHYTFASGSPD-NIKQW 398 Query: 181 NGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDL-----PG 345 G F+ GH A + ++ + D +L+SG+ + T+ +WD R Q + PG Sbjct: 399 KFPDGGFIQNLSGHNAIINTLAVNTDG-VLVSGADNGTMHLWDWRTGYNFQRVHAAVQPG 457 Query: 346 HADE---VYAVDWSPDGEKVVSGGKDRALKLW 432 D ++A + ++++ D+ +K++ Sbjct: 458 SLDSESGIFACAFDRSESRLLTAEADKTIKVY 489 Score = 49.3 bits (116), Expect = 9e-06 Identities = 26/79 (32%), Positives = 40/79 (50%) Frame = +1 Query: 196 KFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDW 375 K GH+ V I+ ++ ++GS D T+K+WD+ + KLK L GH V V Sbjct: 195 KLYRVISGHLGWVRCIAVEPGNQWFVTGSADRTIKIWDLASGKLKLSLTGHISTVRGVIV 254 Query: 376 SPDGEKVVSGGKDRALKLW 432 S + S G+D+ +K W Sbjct: 255 STRSPYLFSCGEDKQVKCW 273
>PLRG1_HUMAN (O43660) Pleiotropic regulator 1| Length = 514 Score = 79.7 bits (195), Expect = 6e-15 Identities = 43/139 (30%), Positives = 70/139 (50%) Frame = +1 Query: 16 VSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITG 195 V+GS D T+ +W+ K K +TGH V V S +L S DK VK W+ Sbjct: 220 VTGSADRTIKIWDLASGKL-KLSLTGHISTVRGVIVSTRSPYLFSCGEDKQVKCWDLEYN 278 Query: 196 KFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDW 375 K + + GH++ VY + +L++ S+DST ++WD+R + L GH + V V Sbjct: 279 KVIRHYHGHLSAVYGLDLHPTIDVLVTCSRDSTARIWDVRTKASVHTLSGHTNAVATVRC 338 Query: 376 SPDGEKVVSGGKDRALKLW 432 ++++G D ++LW Sbjct: 339 QAAEPQIITGSHDTTIRLW 357 Score = 71.6 bits (174), Expect = 2e-12 Identities = 33/116 (28%), Positives = 59/116 (50%) Frame = +1 Query: 85 MTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSR 264 ++GH V + P QW + S D+++K+W+ +GK + GH++ V + S S Sbjct: 200 ISGHLGWVRCIAVEPGNQWFVTGSADRTIKIWDLASGKLKLSLTGHISTVRGVIVSTRSP 259 Query: 265 LLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 L S +D +K WD+ K+ + GH VY +D P + +V+ +D ++W Sbjct: 260 YLFSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYGLDLHPTIDVLVTCSRDSTARIW 315 Score = 56.6 bits (135), Expect = 6e-08 Identities = 39/152 (25%), Positives = 77/152 (50%), Gaps = 8/152 (5%) Frame = +1 Query: 1 APXRLVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLW 180 A ++++GS D T+ LW+ ++ + + +T H+K V V P AS S D ++K W Sbjct: 341 AEPQIITGSHDTTIRLWD-LVAGKTRVTLTNHKKSVRAVVLHPRHYTFASGSPD-NIKQW 398 Query: 181 NGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDL-----PG 345 G F+ GH A + ++ ++D +L+SG+ + T+ +WD R Q + PG Sbjct: 399 KFPDGSFIQNLSGHNAIINTLTVNSDG-VLVSGADNGTMHLWDWRTGYNFQRVHAAVQPG 457 Query: 346 HADE---VYAVDWSPDGEKVVSGGKDRALKLW 432 D ++A + ++++ D+ +K++ Sbjct: 458 SLDSESGIFACAFDQSESRLLTAEADKTIKVY 489 Score = 49.3 bits (116), Expect = 9e-06 Identities = 26/79 (32%), Positives = 40/79 (50%) Frame = +1 Query: 196 KFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDW 375 K GH+ V I+ ++ ++GS D T+K+WD+ + KLK L GH V V Sbjct: 195 KLYRVISGHLGWVRCIAVEPGNQWFVTGSADRTIKIWDLASGKLKLSLTGHISTVRGVIV 254 Query: 376 SPDGEKVVSGGKDRALKLW 432 S + S G+D+ +K W Sbjct: 255 STRSPYLFSCGEDKQVKCW 273
>PLRG1_MOUSE (Q922V4) Pleiotropic regulator 1| Length = 513 Score = 79.7 bits (195), Expect = 6e-15 Identities = 43/139 (30%), Positives = 70/139 (50%) Frame = +1 Query: 16 VSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITG 195 V+GS D T+ +W+ K K +TGH V V S +L S DK VK W+ Sbjct: 219 VTGSADRTIKIWDLASGKL-KLSLTGHISTVRGVIVSTRSPYLFSCGEDKQVKCWDLEYN 277 Query: 196 KFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDW 375 K + + GH++ VY + +L++ S+DST ++WD+R + L GH + V V Sbjct: 278 KVIRHYHGHLSAVYGLDLHPTLDVLVTCSRDSTARIWDVRTKASVHTLSGHTNAVATVRC 337 Query: 376 SPDGEKVVSGGKDRALKLW 432 ++++G D ++LW Sbjct: 338 QAAEPQIITGSHDTTIRLW 356 Score = 71.6 bits (174), Expect = 2e-12 Identities = 33/116 (28%), Positives = 59/116 (50%) Frame = +1 Query: 85 MTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSR 264 ++GH V + P QW + S D+++K+W+ +GK + GH++ V + S S Sbjct: 199 ISGHLGWVRCIAVEPGNQWFVTGSADRTIKIWDLASGKLKLSLTGHISTVRGVIVSTRSP 258 Query: 265 LLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 L S +D +K WD+ K+ + GH VY +D P + +V+ +D ++W Sbjct: 259 YLFSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYGLDLHPTLDVLVTCSRDSTARIW 314 Score = 55.1 bits (131), Expect = 2e-07 Identities = 40/152 (26%), Positives = 77/152 (50%), Gaps = 8/152 (5%) Frame = +1 Query: 1 APXRLVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLW 180 A ++++GS D T+ LW+ ++ + + +T H+K V V P AS S D ++K W Sbjct: 340 AEPQIITGSHDTTIRLWD-LVAGKTRVTLTNHKKSVRAVVLHPLLYTFASGSPD-NIKQW 397 Query: 181 NGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDL-----PG 345 G F+ GH A + ++ +AD +L+SG+ + T+ +WD R Q + PG Sbjct: 398 KFPDGGFIQNLSGHNAIINTLAVNADG-VLVSGADNGTMHLWDWRTGYNFQRVHAAVQPG 456 Query: 346 HADE---VYAVDWSPDGEKVVSGGKDRALKLW 432 D ++A + ++++ D+ +K++ Sbjct: 457 SLDSESGIFACAFDRSESRLLTAEADKTIKVY 488 Score = 49.3 bits (116), Expect = 9e-06 Identities = 26/79 (32%), Positives = 40/79 (50%) Frame = +1 Query: 196 KFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDW 375 K GH+ V I+ ++ ++GS D T+K+WD+ + KLK L GH V V Sbjct: 194 KLYRVISGHLGWVRCIAVEPGNQWFVTGSADRTIKIWDLASGKLKLSLTGHISTVRGVIV 253 Query: 376 SPDGEKVVSGGKDRALKLW 432 S + S G+D+ +K W Sbjct: 254 STRSPYLFSCGEDKQVKCW 272
>WDR1_XENLA (Q9W7F2) WD-repeat protein 1 (Actin-interacting protein 1) (XAIP1)| Length = 608 Score = 79.7 bits (195), Expect = 6e-15 Identities = 49/109 (44%), Positives = 61/109 (55%), Gaps = 4/109 (3%) Frame = +1 Query: 4 PXRLVSGSDD-FTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLW 180 P RLV+GSDD FL P K M+ H + VN V FSPDG LASA D + L+ Sbjct: 159 PYRLVTGSDDNCCAFLEGPPFKF--KFTMSDHSRFVNCVRFSPDGSKLASAGADGQIFLY 216 Query: 181 NGITGKFVTAFRG---HVADVYQISWSADSRLLLSGSKDSTLKVWDIRA 318 +G TG+ V + G H +Y +SWS D LLS S D T K+WD+ A Sbjct: 217 DGKTGEKVCSLGGSKAHDGGIYAVSWSPDGTQLLSASGDKTTKIWDVAA 265 Score = 35.4 bits (80), Expect = 0.13 Identities = 22/70 (31%), Positives = 33/70 (47%), Gaps = 2/70 (2%) Frame = +1 Query: 10 RLVSGSDDFTMFLWEPTISKQ--PKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWN 183 +L S D +FL++ ++ H + V +SPDG L SAS DK+ K+W+ Sbjct: 203 KLASAGADGQIFLYDGKTGEKVCSLGGSKAHDGGIYAVSWSPDGTQLLSASGDKTTKIWD 262 Query: 184 GITGKFVTAF 213 VT F Sbjct: 263 VAANSAVTTF 272
>PRP46_DEBHA (Q6BU94) Pre-mRNA-splicing factor PRP46 (Pre-mRNA-processing| protein 46) Length = 417 Score = 79.7 bits (195), Expect = 6e-15 Identities = 44/144 (30%), Positives = 75/144 (52%), Gaps = 5/144 (3%) Frame = +1 Query: 16 VSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLW----- 180 V+GS D T+ +W+ S KA +TGH V + S +L S S DK+VK W Sbjct: 138 VTGSSDSTIKIWD-LASLNLKATITGHIMGVRSLAVSSRYPYLFSGSEDKTVKCWDLERT 196 Query: 181 NGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEV 360 N + G + + GHV +Y ++ + LL +G +DS ++VWD+R+R L GH ++ Sbjct: 197 NSLLGCQIRNYHGHVGGIYAMALHPELDLLFTGGRDSVIRVWDLRSRTEIMVLSGHRSDI 256 Query: 361 YAVDWSPDGEKVVSGGKDRALKLW 432 ++ ++++ D ++LW Sbjct: 257 TSIASQIGDPQIITSSMDATIRLW 280 Score = 60.1 bits (144), Expect = 5e-09 Identities = 33/119 (27%), Positives = 59/119 (49%), Gaps = 6/119 (5%) Frame = +1 Query: 94 HQKVVNHVYFSP-DGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLL 270 HQ V P +W + S D ++K+W+ + GH+ V ++ S+ L Sbjct: 120 HQGWVRSCTVDPVTNKWFVTGSSDSTIKIWDLASLNLKATITGHIMGVRSLAVSSRYPYL 179 Query: 271 LSGSKDSTLKVWDI-RARKLK----QDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 SGS+D T+K WD+ R L ++ GH +YA+ P+ + + +GG+D +++W Sbjct: 180 FSGSEDKTVKCWDLERTNSLLGCQIRNYHGHVGGIYAMALHPELDLLFTGGRDSVIRVW 238
>TAF73_SCHPO (O74319) Transcription initiation factor TFIID subunit taf73| (Transcription initiation factor TFIID 73 kDa subunit) (TAFII-73) Length = 642 Score = 79.3 bits (194), Expect = 8e-15 Identities = 45/138 (32%), Positives = 69/138 (50%) Frame = +1 Query: 19 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 198 + S D T LW+ + P GHQ V+ V F P+ +LA+ S D + ++W+ TG Sbjct: 462 TASHDQTARLWDVEHAA-PLRVFVGHQNDVDCVSFHPNAAYLATGSSDHTTRMWDVRTGG 520 Query: 199 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWS 378 V F H + V + SAD L S + +KVWD+R+ H+ VY++ +S Sbjct: 521 TVRVFNAHHSPVSALCMSADGLSLASADESGIIKVWDLRSSNQHVSFVKHSSIVYSLSFS 580 Query: 379 PDGEKVVSGGKDRALKLW 432 D + +VSGG D + W Sbjct: 581 YDNKILVSGGADTDVNFW 598 Score = 71.2 bits (173), Expect = 2e-12 Identities = 42/140 (30%), Positives = 69/140 (49%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 ++S S+D LW +K + GH + V FSP G + A+AS D++ +LW+ Sbjct: 418 ILSCSEDGFTRLWSKD-TKSTIVKYAGHNAPIWDVQFSPFGYYFATASHDQTARLWDVEH 476 Query: 193 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVD 372 + F GH DV +S+ ++ L +GS D T ++WD+R + H V A+ Sbjct: 477 AAPLRVFVGHQNDVDCVSFHPNAAYLATGSSDHTTRMWDVRTGGTVRVFNAHHSPVSALC 536 Query: 373 WSPDGEKVVSGGKDRALKLW 432 S DG + S + +K+W Sbjct: 537 MSADGLSLASADESGIIKVW 556 Score = 64.3 bits (155), Expect = 3e-10 Identities = 30/119 (25%), Positives = 57/119 (47%) Frame = +1 Query: 76 KARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSA 255 K+ + GH + V V SP +++ S S D +LW+ T + + GH A ++ + +S Sbjct: 396 KSSLIGHTRPVFGVSISPQKEFILSCSEDGFTRLWSKDTKSTIVKYAGHNAPIWDVQFSP 455 Query: 256 DSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 + S D T ++WD+ + GH ++V V + P+ + +G D ++W Sbjct: 456 FGYYFATASHDQTARLWDVEHAAPLRVFVGHQNDVDCVSFHPNAAYLATGSSDHTTRMW 514 Score = 55.5 bits (132), Expect = 1e-07 Identities = 32/108 (29%), Positives = 53/108 (49%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 L +GS D T +W+ + H V+ + S DG LASA +K+W+ + Sbjct: 502 LATGSSDHTTRMWDVRTGGTVRV-FNAHHSPVSALCMSADGLSLASADESGIIKVWDLRS 560 Query: 193 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQD 336 +F H + VY +S+S D+++L+SG D+ + WD+ R D Sbjct: 561 SNQHVSFVKHSSIVYSLSFSYDNKILVSGGADTDVNFWDLTYRNNLSD 608
>PRL1_ARATH (Q42384) PP1/PP2A phosphatases pleiotropic regulator PRL1| Length = 486 Score = 79.0 bits (193), Expect = 1e-14 Identities = 45/138 (32%), Positives = 72/138 (52%) Frame = +1 Query: 19 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 198 +GS D T+ +W+ K +TGH + V + S ++ SA DK VK W+ K Sbjct: 193 TGSADRTIKIWDVATGVL-KLTLTGHIEQVRGLAVSNRHTYMFSAGDDKQVKCWDLEQNK 251 Query: 199 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWS 378 + ++ GH++ VY ++ +LL+G +DS +VWDIR + L GH + V +V Sbjct: 252 VIRSYHGHLSGVYCLALHPTLDVLLTGGRDSVCRVWDIRTKMQIFALSGHDNTVCSVFTR 311 Query: 379 PDGEKVVSGGKDRALKLW 432 P +VV+G D +K W Sbjct: 312 PTDPQVVTGSHDTTIKFW 329 Score = 72.0 bits (175), Expect = 1e-12 Identities = 32/114 (28%), Positives = 55/114 (48%) Frame = +1 Query: 91 GHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLL 270 GH V V F P +W + S D+++K+W+ TG GH+ V ++ S + Sbjct: 174 GHLGWVRSVAFDPSNEWFCTGSADRTIKIWDVATGVLKLTLTGHIEQVRGLAVSNRHTYM 233 Query: 271 LSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 S D +K WD+ K+ + GH VY + P + +++GG+D ++W Sbjct: 234 FSAGDDKQVKCWDLEQNKVIRSYHGHLSGVYCLALHPTLDVLLTGGRDSVCRVW 287 Score = 47.8 bits (112), Expect = 3e-05 Identities = 22/73 (30%), Positives = 38/73 (52%) Frame = +1 Query: 214 RGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEK 393 +GH+ V +++ + +GS D T+K+WD+ LK L GH ++V + S Sbjct: 173 QGHLGWVRSVAFDPSNEWFCTGSADRTIKIWDVATGVLKLTLTGHIEQVRGLAVSNRHTY 232 Query: 394 VVSGGKDRALKLW 432 + S G D+ +K W Sbjct: 233 MFSAGDDKQVKCW 245 Score = 40.0 bits (92), Expect = 0.005 Identities = 33/149 (22%), Positives = 66/149 (44%), Gaps = 8/149 (5%) Frame = +1 Query: 10 RLVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGI 189 ++V+GS D T+ W+ K + +T H+K V + P ASAS D + K ++ Sbjct: 316 QVVTGSHDTTIKFWDLRYGKT-MSTLTHHKKSVRAMTLHPKENAFASASADNTKK-FSLP 373 Query: 190 TGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDL-----PGHAD 354 G+F + + ++++G + ++ WD ++ Q PG + Sbjct: 374 KGEFCHNMLSQQKTIINAMAVNEDGVMVTGGDNGSIWFWDWKSGHSFQQSETIVQPGSLE 433 Query: 355 E---VYAVDWSPDGEKVVSGGKDRALKLW 432 +YA + G ++V+ D+ +K+W Sbjct: 434 SEAGIYAACYDNTGSRLVTCEADKTIKMW 462
>WDR1_CHICK (O93277) WD-repeat protein 1 (Actin-interacting protein 1) (AIP1)| Length = 609 Score = 78.6 bits (192), Expect = 1e-14 Identities = 47/111 (42%), Positives = 62/111 (55%), Gaps = 3/111 (2%) Frame = +1 Query: 4 PXRLVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWN 183 P RL +GSDD +E K K ++ H + VN V FSPDG A+AS D + +++ Sbjct: 161 PYRLATGSDDNCAAFFEGPPFKF-KFTLSDHTRFVNCVRFSPDGNRFATASADGQIFIYD 219 Query: 184 GITGKFVTAFRG---HVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKL 327 G TG+ V A G H +Y ISWS DS LLS S D T K+WD+ A + Sbjct: 220 GKTGEKVCALGGGKAHDGGIYAISWSPDSSQLLSASGDKTAKIWDVGANSV 270 Score = 59.3 bits (142), Expect = 9e-09 Identities = 38/135 (28%), Positives = 60/135 (44%), Gaps = 4/135 (2%) Frame = +1 Query: 40 MFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQW-LASASFDKSVKLWNGITGKFVTAFR 216 +FLW+ S +TGH KV+N V + LA+ S D + G KF Sbjct: 132 VFLWD---SGSSVGEITGHNKVINSVDIKQTRPYRLATGSDDNCAAFFEGPPFKFKFTLS 188 Query: 217 GHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPG---HADEVYAVDWSPDG 387 H V + +S D + S D + ++D + + L G H +YA+ WSPD Sbjct: 189 DHTRFVNCVRFSPDGNRFATASADGQIFIYDGKTGEKVCALGGGKAHDGGIYAISWSPDS 248 Query: 388 EKVVSGGKDRALKLW 432 +++S D+ K+W Sbjct: 249 SQLLSASGDKTAKIW 263 Score = 40.8 bits (94), Expect = 0.003 Identities = 31/112 (27%), Positives = 50/112 (44%), Gaps = 3/112 (2%) Frame = +1 Query: 106 VNHVYFSPDGQWLASASFDKSVKLWNGITGKFV-TAFRGHVADVYQISWSADSRLLLSGS 282 V + +S DG +LA +K V +++ G F GH A V I+WS D+ SG Sbjct: 494 VTDLAYSHDGAFLAVCDANKVVTVFSVPDGYVEHNVFYGHHAKVVCIAWSPDNEHFASGG 553 Query: 283 KDSTLKVWDIRARKLKQDLPG--HADEVYAVDWSPDGEKVVSGGKDRALKLW 432 D + VW + + + +P V + W D +V+ D ++K W Sbjct: 554 MDMMVYVWTVSDPETRIKIPDAHRLHHVSGLAWL-DEHTLVTTSHDASVKEW 604 Score = 35.0 bits (79), Expect = 0.17 Identities = 28/109 (25%), Positives = 51/109 (46%), Gaps = 7/109 (6%) Frame = +1 Query: 127 PDGQWLASASFDKSVKLWNGITGKFVTA------FRGHVADVYQISWSADSRLLLSGSKD 288 P G +A D +V+L++ I G + + +G V D +++S D L + Sbjct: 457 PGGGSVAVGGTDGNVRLYS-IQGTSLKSDDKTLEAKGPVTD---LAYSHDGAFLAVCDAN 512 Query: 289 STLKVWDIRARKLKQDL-PGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 + V+ + ++ ++ GH +V + WSPD E SGG D + +W Sbjct: 513 KVVTVFSVPDGYVEHNVFYGHHAKVVCIAWSPDNEHFASGGMDMMVYVW 561 Score = 35.0 bits (79), Expect = 0.17 Identities = 39/150 (26%), Positives = 64/150 (42%), Gaps = 9/150 (6%) Frame = +1 Query: 10 RLVSGSDDFTMFLWEPTISKQPKARMTG--HQKVVNHVYFSPDGQWLASASFDKSVKLWN 183 R + S D +F+++ ++ A G H + + +SPD L SAS DK+ K+W+ Sbjct: 205 RFATASADGQIFIYDGKTGEKVCALGGGKAHDGGIYAISWSPDSSQLLSASGDKTAKIWD 264 Query: 184 GITGKFVTAFR--GHVADVYQIS--WSADSRLLLSGSKDSTLKVWD-IRARKLKQDLPGH 348 V+ F +V D Q+ W D LLS S + D K + + GH Sbjct: 265 VGANSVVSTFNMGSNVLD-QQLGCLWQKDH--LLSLSLSGYINYLDKNNPDKPLRVIKGH 321 Query: 349 ADEVYAVDWSPDGEK--VVSGGKDRALKLW 432 + + + +G K + SG D + W Sbjct: 322 SKSIQCLTVHKNGGKSYIYSGSNDGHINYW 351 Score = 32.0 bits (71), Expect = 1.5 Identities = 24/78 (30%), Positives = 35/78 (44%), Gaps = 4/78 (5%) Frame = +1 Query: 91 GHQKVVNHVYFSPDGQWLASASFDKSVKLWN----GITGKFVTAFRGHVADVYQISWSAD 258 GH V + +SPD + AS D V +W K A R H V ++W D Sbjct: 532 GHHAKVVCIAWSPDNEHFASGGMDMMVYVWTVSDPETRIKIPDAHRLH--HVSGLAW-LD 588 Query: 259 SRLLLSGSKDSTLKVWDI 312 L++ S D+++K W I Sbjct: 589 EHTLVTTSHDASVKEWSI 606
>MET30_YEAST (P39014) F-box protein MET30 (Methionine requiring protein 30) (E3| ubiquitin ligase complex SCF(Met30) subunit MET30) Length = 640 Score = 78.6 bits (192), Expect = 1e-14 Identities = 46/140 (32%), Positives = 77/140 (55%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 L +GS D T+ +W+ K + R++GH V +YF D + L + S DK++++WN IT Sbjct: 315 LFTGSYDSTIGIWDLFTGKLIR-RLSGHSDGVKTLYF--DDRKLITGSLDKTIRVWNYIT 371 Query: 193 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVD 372 G+ ++ +RGH V +S + ++++SGS D T+KVW + +R L GH + V V Sbjct: 372 GECISTYRGHSDSV--LSVDSYQKVIVSGSADKTVKVWHVESRTC-YTLRGHTEWVNCVK 428 Query: 373 WSPDGEKVVSGGKDRALKLW 432 P S D +++W Sbjct: 429 LHPKSFSCFSCSDDTTIRMW 448 Score = 54.3 bits (129), Expect = 3e-07 Identities = 44/187 (23%), Positives = 75/187 (40%), Gaps = 47/187 (25%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 +VSGS D T+ +W + + + GH + VN V P S S D ++++W+ T Sbjct: 395 IVSGSADKTVKVWH--VESRTCYTLRGHTEWVNCVKLHPKSFSCFSCSDDTTIRMWDIRT 452 Query: 193 GKFVTAFRGHVADVYQI-------------------SWSADSRLLLSGSK---------- 285 + FRGHV V +I S D + G+ Sbjct: 453 NSCLKVFRGHVGQVQKIIPLTIKDVENLATDNTSDGSSPQDDPTMTDGADESDTPSNEQE 512 Query: 286 ------------------DSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGK 411 D+T+K+WD++ K + GH + V+ D + D +++SG Sbjct: 513 TVLDENIPYPTHLLSCGLDNTIKLWDVKTGKCIRTQFGHVEGVW--DIAADNFRIISGSH 570 Query: 412 DRALKLW 432 D ++K+W Sbjct: 571 DGSIKVW 577 Score = 52.4 bits (124), Expect = 1e-06 Identities = 26/77 (33%), Positives = 47/77 (61%) Frame = +1 Query: 202 VTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSP 381 + F+GH+ V + ++ RLL +GS DST+ +WD+ KL + L GH+D V + + Sbjct: 295 IQEFKGHMDGVLTLQFNY--RLLFTGSYDSTIGIWDLFTGKLIRRLSGHSDGVKTLYF-- 350 Query: 382 DGEKVVSGGKDRALKLW 432 D K+++G D+ +++W Sbjct: 351 DDRKLITGSLDKTIRVW 367 Score = 51.6 bits (122), Expect = 2e-06 Identities = 26/68 (38%), Positives = 40/68 (58%) Frame = +1 Query: 142 LASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRAR 321 L S D ++KLW+ TGK + GHV V+ I +AD+ ++SGS D ++KVWD+++ Sbjct: 525 LLSCGLDNTIKLWDVKTGKCIRTQFGHVEGVWDI--AADNFRIISGSHDGSIKVWDLQSG 582 Query: 322 KLKQDLPG 345 K G Sbjct: 583 KCMHTFNG 590
>KTNB1_CHICK (Q5ZIU8) Katanin p80 WD40-containing subunit B1 (Katanin p80| subunit B1) (p80 katanin) Length = 657 Score = 78.6 bits (192), Expect = 1e-14 Identities = 40/140 (28%), Positives = 74/140 (52%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 +V+GS ++ +W+ +K + + GH+ + + F P G ++AS S D +KLW+ Sbjct: 77 IVAGSQSGSIRVWDLEAAKILRT-LLGHKANICSLDFHPYGSFVASGSLDTDIKLWDVRR 135 Query: 193 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVD 372 + ++ H V + +S D + L S + D T+K+WD+ A K+ + GH+ V V+ Sbjct: 136 KGCIFKYKSHTQAVRCLRFSPDGKWLASAADDHTVKLWDLTAGKVMFEFTGHSGPVNVVE 195 Query: 373 WSPDGEKVVSGGKDRALKLW 432 + P + SG DR ++ W Sbjct: 196 FHPSEYLLASGSSDRTIRFW 215 Score = 78.2 bits (191), Expect = 2e-14 Identities = 46/134 (34%), Positives = 69/134 (51%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 + SGS D + LW+ K + H + V + FSPDG+WLASA+ D +VKLW+ Sbjct: 119 VASGSLDTDIKLWDVR-RKGCIFKYKSHTQAVRCLRFSPDGKWLASAADDHTVKLWDLTA 177 Query: 193 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVD 372 GK + F GH V + + LL SGS D T++ WD+ + + A V + Sbjct: 178 GKVMFEFTGHSGPVNVVEFHPSEYLLASGSSDRTIRFWDLEKFHVVSCIEEEATPVRCIL 237 Query: 373 WSPDGEKVVSGGKD 414 ++PDG + G +D Sbjct: 238 FNPDGCCLYGGFQD 251 Score = 72.8 bits (177), Expect = 7e-13 Identities = 36/140 (25%), Positives = 68/140 (48%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 L +G DD + +W ++ Q + +TGH + + S + + + S S+++W+ Sbjct: 36 LATGGDDCQVNVW--SVKAQLRHELTGHTTPIESLQISAKEELIVAGSQSGSIRVWDLEA 93 Query: 193 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVD 372 K + GH A++ + + + SGS D+ +K+WD+R + H V + Sbjct: 94 AKILRTLLGHKANICSLDFHPYGSFVASGSLDTDIKLWDVRRKGCIFKYKSHTQAVRCLR 153 Query: 373 WSPDGEKVVSGGKDRALKLW 432 +SPDG+ + S D +KLW Sbjct: 154 FSPDGKWLASAADDHTVKLW 173 Score = 47.4 bits (111), Expect = 3e-05 Identities = 31/93 (33%), Positives = 43/93 (46%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 L S +DD T+ LW+ T K TGH VN V F P LAS S D++++ W+ Sbjct: 161 LASAADDHTVKLWDLTAGKV-MFEFTGHSGPVNVVEFHPSEYLLASGSSDRTIRFWDLEK 219 Query: 193 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDS 291 V+ V I ++ D L G +DS Sbjct: 220 FHVVSCIEEEATPVRCILFNPDGCCLYGGFQDS 252 Score = 40.0 bits (92), Expect = 0.005 Identities = 17/57 (29%), Positives = 34/57 (59%) Frame = +1 Query: 262 RLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 RLL +G D + VW ++A +L+ +L GH + ++ S E +V+G + ++++W Sbjct: 34 RLLATGGDDCQVNVWSVKA-QLRHELTGHTTPIESLQISAKEELIVAGSQSGSIRVW 89
>TBL1Y_HUMAN (Q9BQ87) F-box-like/WD-repeat protein TBL1Y (Transducin beta-like| 1Y protein) (Transducin-beta-like 1, Y-linked) Length = 522 Score = 78.2 bits (191), Expect = 2e-14 Identities = 42/129 (32%), Positives = 64/129 (49%), Gaps = 9/129 (6%) Frame = +1 Query: 73 PKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWS 252 P GH VN + + P G LAS S D ++K+W+ V + H ++Y I WS Sbjct: 351 PVKTFQGHTNEVNAIKWDPSGMLLASCSDDMTLKIWSMKQDACVHDLQAHSKEIYTIKWS 410 Query: 253 A---------DSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSG 405 S +L S S DST+++WD+ L H + VY+V +SPDG+ + SG Sbjct: 411 PTGPATSNPNSSIMLASASFDSTVRLWDVEQGVCTHTLMKHQEPVYSVAFSPDGKYLASG 470 Query: 406 GKDRALKLW 432 D+ + +W Sbjct: 471 SFDKYVHIW 479 Score = 65.1 bits (157), Expect = 2e-10 Identities = 44/145 (30%), Positives = 67/145 (46%), Gaps = 11/145 (7%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKA--RMTGHQKVVNHVYFSPDGQ---------WLASASF 159 L S SDD T+ +W KQ + H K + + +SP G LASASF Sbjct: 374 LASCSDDMTLKIWS---MKQDACVHDLQAHSKEIYTIKWSPTGPATSNPNSSIMLASASF 430 Query: 160 DKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDL 339 D +V+LW+ G H VY +++S D + L SGS D + +W+ ++ L Sbjct: 431 DSTVRLWDVEQGVCTHTLMKHQEPVYSVAFSPDGKYLASGSFDKYVHIWNTQSGSLVHSY 490 Query: 340 PGHADEVYAVDWSPDGEKVVSGGKD 414 G ++ V W+ G+KV + D Sbjct: 491 QG-TGGIFEVCWNARGDKVGASASD 514 Score = 60.8 bits (146), Expect = 3e-09 Identities = 35/100 (35%), Positives = 56/100 (56%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 L S S D T+ LW+ M HQ+ V V FSPDG++LAS SFDK V +WN + Sbjct: 425 LASASFDSTVRLWDVEQGVCTHTLMK-HQEPVYSVAFSPDGKYLASGSFDKYVHIWNTQS 483 Query: 193 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDI 312 G V +++G ++++ W+A + + + D ++ V D+ Sbjct: 484 GSLVHSYQG-TGGIFEVCWNARGDKVGASASDGSVCVLDL 522 Score = 59.7 bits (143), Expect = 7e-09 Identities = 40/149 (26%), Positives = 61/149 (40%), Gaps = 9/149 (6%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 ++S D T +W+ + K + H V + + AS S D + + Sbjct: 291 VLSAGVDKTTIIWDAHTG-EAKQQFPFHSAPALDVDWQ-NNMTFASCSTDMCIHVCRLGC 348 Query: 193 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVD 372 V F+GH +V I W LL S S D TLK+W ++ DL H+ E+Y + Sbjct: 349 DHPVKTFQGHTNEVNAIKWDPSGMLLASCSDDMTLKIWSMKQDACVHDLQAHSKEIYTIK 408 Query: 373 WSPDGE---------KVVSGGKDRALKLW 432 WSP G + S D ++LW Sbjct: 409 WSPTGPATSNPNSSIMLASASFDSTVRLW 437 Score = 55.8 bits (133), Expect = 9e-08 Identities = 44/194 (22%), Positives = 65/194 (33%), Gaps = 54/194 (27%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKA---------RMTGHQ----KVVNHVYFSPDGQWLASA 153 L SGS D T +W + + R GH K V + ++ DG LA Sbjct: 194 LASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDVPSNKDVTSLDWNSDGTLLAMG 253 Query: 154 SFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQ 333 S+D ++W G + H ++ + W+ +LS D T +WD + KQ Sbjct: 254 SYDGFARIWTE-NGNLASTLGQHKGPIFALKWNKKGNYVLSAGVDKTTIIWDAHTGEAKQ 312 Query: 334 DLP-----------------------------------------GHADEVYAVDWSPDGE 390 P GH +EV A+ W P G Sbjct: 313 QFPFHSAPALDVDWQNNMTFASCSTDMCIHVCRLGCDHPVKTFQGHTNEVNAIKWDPSGM 372 Query: 391 KVVSGGKDRALKLW 432 + S D LK+W Sbjct: 373 LLASCSDDMTLKIW 386 Score = 53.1 bits (126), Expect = 6e-07 Identities = 36/130 (27%), Positives = 57/130 (43%), Gaps = 14/130 (10%) Frame = +1 Query: 85 MTGHQKVVNHVYFSPDGQWLASASFDKSVKLW------NGITGKFVTAF----RGHVA-- 228 + GH+ V ++P LAS S D + ++W NG + + V GH Sbjct: 175 LRGHESEVFICAWNPVSDLLASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDVPS 234 Query: 229 --DVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVS 402 DV + W++D LL GS D ++W L L H ++A+ W+ G V+S Sbjct: 235 NKDVTSLDWNSDGTLLAMGSYDGFARIWTENG-NLASTLGQHKGPIFALKWNKKGNYVLS 293 Query: 403 GGKDRALKLW 432 G D+ +W Sbjct: 294 AGVDKTTIIW 303 Score = 51.6 bits (122), Expect = 2e-06 Identities = 28/91 (30%), Positives = 46/91 (50%), Gaps = 15/91 (16%) Frame = +1 Query: 205 TAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIR---------------ARKLKQDL 339 T RGH ++V+ +W+ S LL SGS DST ++W++ R+ D+ Sbjct: 173 TVLRGHESEVFICAWNPVSDLLASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDV 232 Query: 340 PGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 P + D V ++DW+ DG + G D ++W Sbjct: 233 PSNKD-VTSLDWNSDGTLLAMGSYDGFARIW 262
>PRP46_CANAL (Q5A7Q3) Pre-mRNA-splicing factor PRP46 (Pre-mRNA-processing| protein 46) Length = 389 Score = 78.2 bits (191), Expect = 2e-14 Identities = 43/144 (29%), Positives = 75/144 (52%), Gaps = 5/144 (3%) Frame = +1 Query: 16 VSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLW----- 180 V+GS D T+ +W+ + KA +TGH + + S +L S DKS++ W Sbjct: 102 VTGSADSTIKIWDFE-NNSLKAVLTGHVLGIRSLCISKRHPYLFSGGEDKSLRCWDLERS 160 Query: 181 NGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEV 360 N G + ++ GH+ VY I + +L SG KD ++VWDIR+R L GH +++ Sbjct: 161 NSDAGCQIRSYHGHLGGVYSIGLHPELDVLFSGGKDCVVRVWDIRSRVEAMTLLGHTNDI 220 Query: 361 YAVDWSPDGEKVVSGGKDRALKLW 432 +++ + +V++ D ++LW Sbjct: 221 TSIETDYNDPQVITSSMDGTIRLW 244 Score = 56.2 bits (134), Expect = 7e-08 Identities = 27/104 (25%), Positives = 48/104 (46%), Gaps = 5/104 (4%) Frame = +1 Query: 136 QWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIR 315 +W + S D ++K+W+ GHV + + S L SG +D +L+ WD+ Sbjct: 99 KWYVTGSADSTIKIWDFENNSLKAVLTGHVLGIRSLCISKRHPYLFSGGEDKSLRCWDLE 158 Query: 316 ARKLK-----QDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 + GH VY++ P+ + + SGGKD +++W Sbjct: 159 RSNSDAGCQIRSYHGHLGGVYSIGLHPELDVLFSGGKDCVVRVW 202
>TRCB_XENLA (Q91854) Beta-TrCP (Beta-transducin repeat-containing protein)| Length = 518 Score = 78.2 bits (191), Expect = 2e-14 Identities = 45/142 (31%), Positives = 80/142 (56%), Gaps = 2/142 (1%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKAR--MTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNG 186 +V+ S D ++ +W+ + R + GH+ VN V F D +++ SAS D+++K+WN Sbjct: 325 MVTCSKDRSIAVWDMASATDITLRRVLVGHRAAVNVVDF--DDKYIVSASGDRTIKVWNT 382 Query: 187 ITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYA 366 T +FV GH + + + RL++SGS D+T+++WDI + L GH + V Sbjct: 383 STCEFVRTLNGHKRGIACLQYR--DRLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRC 440 Query: 367 VDWSPDGEKVVSGGKDRALKLW 432 + + D +++VSG D +K+W Sbjct: 441 IRF--DNKRIVSGAYDGKIKVW 460 Score = 57.0 bits (136), Expect = 4e-08 Identities = 40/149 (26%), Positives = 78/149 (52%), Gaps = 3/149 (2%) Frame = +1 Query: 10 RLVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGI 189 ++VSG D T+ +W+ + + K + GH V + + D + + + S D +V++W+ Sbjct: 244 KIVSGLRDNTIKIWDKN-TLECKRVLMGHTGSVLCLQY--DERVIITGSSDSTVRVWDVN 300 Query: 190 TGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRAR---KLKQDLPGHADEV 360 TG+ + H V + ++ + ++++ SKD ++ VWD+ + L++ L GH V Sbjct: 301 TGEMLNTLIHHCEAVLHLRFN--NGMMVTCSKDRSIAVWDMASATDITLRRVLVGHRAAV 358 Query: 361 YAVDWSPDGEKVVSGGKDRALKLWMN*AC 447 VD+ D + +VS DR +K+W C Sbjct: 359 NVVDF--DDKYIVSASGDRTIKVWNTSTC 385 Score = 53.5 bits (127), Expect = 5e-07 Identities = 28/101 (27%), Positives = 54/101 (53%) Frame = +1 Query: 130 DGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWD 309 D Q + S D ++K+W+ T + GH V + + D R++++GS DST++VWD Sbjct: 241 DDQKIVSGLRDNTIKIWDKNTLECKRVLMGHTGSVLCLQY--DERVIITGSSDSTVRVWD 298 Query: 310 IRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 + ++ L H + V + + + +V+ KDR++ +W Sbjct: 299 VNTGEMLNTLIHHCEAVLHLRF--NNGMMVTCSKDRSIAVW 337
>GBLP_LEIMA (Q25306) Guanine nucleotide-binding protein beta subunit-like| protein (Antigen LACK) Length = 312 Score = 77.8 bits (190), Expect = 2e-14 Identities = 50/143 (34%), Positives = 80/143 (55%), Gaps = 4/143 (2%) Frame = +1 Query: 16 VSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITG 195 ++ S D ++ +W+ + Q + + H K V V FSPD + + SA D +++WN + G Sbjct: 81 LTASWDRSIRMWDLR-NGQCQRKFLKHTKDVLAVAFSPDDRLIVSAGRDNVIRVWN-VAG 138 Query: 196 KFVTAFR--GHVADVYQISWSA--DSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVY 363 + + F GH V I +S + +++SGS D+T+KVW++ K ++ L GH++ V Sbjct: 139 ECMHEFLRDGHEDWVSSICFSPSLEHPIVVSGSWDNTIKVWNVNGGKCERTLKGHSNYVS 198 Query: 364 AVDWSPDGEKVVSGGKDRALKLW 432 V SPDG SGGKD A LW Sbjct: 199 TVTVSPDGSLCASGGKDGAALLW 221 Score = 77.0 bits (188), Expect = 4e-14 Identities = 45/152 (29%), Positives = 80/152 (52%), Gaps = 11/152 (7%) Frame = +1 Query: 10 RLVSGSDDFTMFLWEPTISKQ--------PKARMTGHQKVVNHVYFSPDGQWLASASFDK 165 ++VS S D T+ W+ + P R+ GH V+ V + + +AS+D+ Sbjct: 28 KVVSTSRDGTVISWKANPDRHSVDSDYGLPNHRLEGHTGFVSCVSLAHATDYALTASWDR 87 Query: 166 SVKLWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDL-P 342 S+++W+ G+ F H DV +++S D RL++S +D+ ++VW++ + + L Sbjct: 88 SIRMWDLRNGQCQRKFLKHTKDVLAVAFSPDDRLIVSAGRDNVIRVWNVAGECMHEFLRD 147 Query: 343 GHADEVYAVDWSPDGEK--VVSGGKDRALKLW 432 GH D V ++ +SP E VVSG D +K+W Sbjct: 148 GHEDWVSSICFSPSLEHPIVVSGSWDNTIKVW 179 Score = 60.1 bits (144), Expect = 5e-09 Identities = 43/144 (29%), Positives = 74/144 (51%), Gaps = 4/144 (2%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 +VSGS D T+ +W K + + GH V+ V SPDG AS D + LW+ T Sbjct: 167 VVSGSWDNTIKVWNVNGGKCERT-LKGHSNYVSTVTVSPDGSLCASGGKDGAALLWDLST 225 Query: 193 GKFVTAFRGHV-ADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLP---GHADEV 360 G+ F+ +V + + QI +S +R + + + +L V+D+ ++ + +L E Sbjct: 226 GE--QLFKINVESPINQIGFS-PNRFWMCVATERSLSVYDLESKAVIAELTPDGAKPSEC 282 Query: 361 YAVDWSPDGEKVVSGGKDRALKLW 432 ++ WS DG + SG KD +++W Sbjct: 283 ISIAWSADGNTLYSGHKDNLIRVW 306
>GBLP_LEIIN (P62884) Guanine nucleotide-binding protein beta subunit-like| protein (Antigen LACK) (LiP36) (p36Li) Length = 312 Score = 77.8 bits (190), Expect = 2e-14 Identities = 50/143 (34%), Positives = 80/143 (55%), Gaps = 4/143 (2%) Frame = +1 Query: 16 VSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITG 195 ++ S D ++ +W+ + Q + + H K V V FSPD + + SA D +++WN + G Sbjct: 81 LTASWDRSIRMWDLR-NGQCQRKFLKHTKDVLAVAFSPDDRLIVSAGRDNVIRVWN-VAG 138 Query: 196 KFVTAFR--GHVADVYQISWSA--DSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVY 363 + + F GH V I +S + +++SGS D+T+KVW++ K ++ L GH++ V Sbjct: 139 ECMHEFLRDGHEDWVSSICFSPSLEHPIVVSGSWDNTIKVWNVNGGKCERTLKGHSNYVS 198 Query: 364 AVDWSPDGEKVVSGGKDRALKLW 432 V SPDG SGGKD A LW Sbjct: 199 TVTVSPDGSLCASGGKDGAALLW 221 Score = 76.3 bits (186), Expect = 7e-14 Identities = 45/152 (29%), Positives = 79/152 (51%), Gaps = 11/152 (7%) Frame = +1 Query: 10 RLVSGSDDFTMFLWEPTISKQ--------PKARMTGHQKVVNHVYFSPDGQWLASASFDK 165 ++VS S D T W+ + P R+ GH V+ V + + +AS+D+ Sbjct: 28 KVVSTSRDGTAISWKANPDRHSVDSDYGLPSHRLEGHTGFVSCVSLAHATDYALTASWDR 87 Query: 166 SVKLWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDL-P 342 S+++W+ G+ F H DV +++S D RL++S +D+ ++VW++ + + L Sbjct: 88 SIRMWDLRNGQCQRKFLKHTKDVLAVAFSPDDRLIVSAGRDNVIRVWNVAGECMHEFLRD 147 Query: 343 GHADEVYAVDWSPDGEK--VVSGGKDRALKLW 432 GH D V ++ +SP E VVSG D +K+W Sbjct: 148 GHEDWVSSICFSPSLEHPIVVSGSWDNTIKVW 179 Score = 60.5 bits (145), Expect = 4e-09 Identities = 43/144 (29%), Positives = 75/144 (52%), Gaps = 4/144 (2%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 +VSGS D T+ +W K + + GH V+ V SPDG AS D + LW+ T Sbjct: 167 VVSGSWDNTIKVWNVNGGKCERT-LKGHSNYVSTVTVSPDGSLCASGGKDGAALLWDLST 225 Query: 193 GKFVTAFRGHV-ADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLP---GHADEV 360 G+ F+ +V + + QI++S +R + + + +L V+D+ ++ + +L E Sbjct: 226 GE--QLFKINVESPINQIAFS-PNRFWMCVATERSLSVYDLESKAVIAELTPDGAKPSEC 282 Query: 361 YAVDWSPDGEKVVSGGKDRALKLW 432 ++ WS DG + SG KD +++W Sbjct: 283 ISIAWSADGNTLYSGHKDNLIRVW 306 Score = 43.9 bits (102), Expect = 4e-04 Identities = 29/102 (28%), Positives = 51/102 (50%), Gaps = 4/102 (3%) Frame = +1 Query: 19 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 198 SG D LW+ + +Q + +N + FSP+ W+ A+ ++S+ +++ + K Sbjct: 211 SGGKDGAALLWDLSTGEQ--LFKINVESPINQIAFSPNRFWMCVAT-ERSLSVYD-LESK 266 Query: 199 FV----TAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDI 312 V T ++ I+WSAD L SG KD+ ++VW I Sbjct: 267 AVIAELTPDGAKPSECISIAWSADGNTLYSGHKDNLIRVWSI 308
>GBLP_LEICH (P62883) Guanine nucleotide-binding protein beta subunit-like| protein (Antigen LACK) Length = 312 Score = 77.8 bits (190), Expect = 2e-14 Identities = 50/143 (34%), Positives = 80/143 (55%), Gaps = 4/143 (2%) Frame = +1 Query: 16 VSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITG 195 ++ S D ++ +W+ + Q + + H K V V FSPD + + SA D +++WN + G Sbjct: 81 LTASWDRSIRMWDLR-NGQCQRKFLKHTKDVLAVAFSPDDRLIVSAGRDNVIRVWN-VAG 138 Query: 196 KFVTAFR--GHVADVYQISWSA--DSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVY 363 + + F GH V I +S + +++SGS D+T+KVW++ K ++ L GH++ V Sbjct: 139 ECMHEFLRDGHEDWVSSICFSPSLEHPIVVSGSWDNTIKVWNVNGGKCERTLKGHSNYVS 198 Query: 364 AVDWSPDGEKVVSGGKDRALKLW 432 V SPDG SGGKD A LW Sbjct: 199 TVTVSPDGSLCASGGKDGAALLW 221 Score = 76.3 bits (186), Expect = 7e-14 Identities = 45/152 (29%), Positives = 79/152 (51%), Gaps = 11/152 (7%) Frame = +1 Query: 10 RLVSGSDDFTMFLWEPTISKQ--------PKARMTGHQKVVNHVYFSPDGQWLASASFDK 165 ++VS S D T W+ + P R+ GH V+ V + + +AS+D+ Sbjct: 28 KVVSTSRDGTAISWKANPDRHSVDSDYGLPSHRLEGHTGFVSCVSLAHATDYALTASWDR 87 Query: 166 SVKLWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDL-P 342 S+++W+ G+ F H DV +++S D RL++S +D+ ++VW++ + + L Sbjct: 88 SIRMWDLRNGQCQRKFLKHTKDVLAVAFSPDDRLIVSAGRDNVIRVWNVAGECMHEFLRD 147 Query: 343 GHADEVYAVDWSPDGEK--VVSGGKDRALKLW 432 GH D V ++ +SP E VVSG D +K+W Sbjct: 148 GHEDWVSSICFSPSLEHPIVVSGSWDNTIKVW 179 Score = 60.5 bits (145), Expect = 4e-09 Identities = 43/144 (29%), Positives = 75/144 (52%), Gaps = 4/144 (2%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 +VSGS D T+ +W K + + GH V+ V SPDG AS D + LW+ T Sbjct: 167 VVSGSWDNTIKVWNVNGGKCERT-LKGHSNYVSTVTVSPDGSLCASGGKDGAALLWDLST 225 Query: 193 GKFVTAFRGHV-ADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLP---GHADEV 360 G+ F+ +V + + QI++S +R + + + +L V+D+ ++ + +L E Sbjct: 226 GE--QLFKINVESPINQIAFS-PNRFWMCVATERSLSVYDLESKAVIAELTPDGAKPSEC 282 Query: 361 YAVDWSPDGEKVVSGGKDRALKLW 432 ++ WS DG + SG KD +++W Sbjct: 283 ISIAWSADGNTLYSGHKDNLIRVW 306 Score = 43.9 bits (102), Expect = 4e-04 Identities = 29/102 (28%), Positives = 51/102 (50%), Gaps = 4/102 (3%) Frame = +1 Query: 19 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 198 SG D LW+ + +Q + +N + FSP+ W+ A+ ++S+ +++ + K Sbjct: 211 SGGKDGAALLWDLSTGEQ--LFKINVESPINQIAFSPNRFWMCVAT-ERSLSVYD-LESK 266 Query: 199 FV----TAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDI 312 V T ++ I+WSAD L SG KD+ ++VW I Sbjct: 267 AVIAELTPDGAKPSECISIAWSADGNTLYSGHKDNLIRVWSI 308
>PEX7_HUMAN (O00628) Peroxisomal targeting signal 2 receptor (PTS2 receptor)| (Peroxin-7) Length = 323 Score = 77.8 bits (190), Expect = 2e-14 Identities = 46/144 (31%), Positives = 75/144 (52%), Gaps = 4/144 (2%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDG--QWLASASFDKSVKLWNG 186 L++ S D ++ LW+ + P H + V V +S Q + S S+D++VKLW+ Sbjct: 83 LITCSGDGSLQLWDTAKAAGPLQVYKEHAQEVYSVDWSQTRGEQLVVSGSWDQTVKLWDP 142 Query: 187 ITGKFVTAFRGHVADVYQISWSAD-SRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVY 363 GK + FRGH + +Y WS S S D TL++WD++A ++ +P H E+ Sbjct: 143 TVGKSLCTFRGHESIIYSTIWSPHIPGCFASASGDQTLRIWDVKAAGVRIVIPAHQAEIL 202 Query: 364 AVDWSPDGEK-VVSGGKDRALKLW 432 + DW E +V+G D +L+ W Sbjct: 203 SCDWCKYNENLLVTGAVDCSLRGW 226 Score = 41.2 bits (95), Expect = 0.002 Identities = 29/102 (28%), Positives = 48/102 (47%), Gaps = 3/102 (2%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSP-DGQWLASASFDKSVKLWN-G 186 LV+G+ D ++ W+ +QP + GH + V FSP LAS S+D +V+ WN Sbjct: 214 LVTGAVDCSLRGWDLRNVRQPVFELLGHTYAIRRVKFSPFHASVLASCSYDFTVRFWNFS 273 Query: 187 ITGKFVTAFRGHVADVYQISWSADSRLLLSG-SKDSTLKVWD 309 + H + +S S ++ S D T+K++D Sbjct: 274 KPDSLLETVEHHTEFTCGLDFSLQSPTQVADCSWDETIKIYD 315
>TBLX_MOUSE (Q9QXE7) F-box-like/WD-repeat protein TBL1X (Transducin beta-like| 1X protein) Length = 527 Score = 77.8 bits (190), Expect = 2e-14 Identities = 41/130 (31%), Positives = 65/130 (50%), Gaps = 9/130 (6%) Frame = +1 Query: 70 QPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISW 249 +P GH VN + + P G LAS S D ++K+W+ V + H ++Y I W Sbjct: 353 RPVKTFQGHTNEVNAIKWDPSGMLLASCSDDMTLKIWSMKQDACVHDLQAHSKEIYTIKW 412 Query: 250 SA---------DSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVS 402 S + +L S S DST+++WD+ L H + VY+V +SPDG+ + S Sbjct: 413 SPTGPATSNPNSNIMLASASFDSTVRLWDVERGVCIHTLTKHQEPVYSVAFSPDGKYLAS 472 Query: 403 GGKDRALKLW 432 G D+ + +W Sbjct: 473 GSFDKCVHIW 482 Score = 66.2 bits (160), Expect = 7e-11 Identities = 44/145 (30%), Positives = 68/145 (46%), Gaps = 11/145 (7%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKA--RMTGHQKVVNHVYFSPDGQ---------WLASASF 159 L S SDD T+ +W KQ + H K + + +SP G LASASF Sbjct: 377 LASCSDDMTLKIWS---MKQDACVHDLQAHSKEIYTIKWSPTGPATSNPNSNIMLASASF 433 Query: 160 DKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDL 339 D +V+LW+ G + H VY +++S D + L SGS D + +W+ ++ L Sbjct: 434 DSTVRLWDVERGVCIHTLTKHQEPVYSVAFSPDGKYLASGSFDKCVHIWNTQSGSLVHSY 493 Query: 340 PGHADEVYAVDWSPDGEKVVSGGKD 414 G ++ V W+ G+KV + D Sbjct: 494 RG-TGGIFEVCWNARGDKVGASASD 517 Score = 65.1 bits (157), Expect = 2e-10 Identities = 37/101 (36%), Positives = 58/101 (57%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 L S S D T+ LW+ +T HQ+ V V FSPDG++LAS SFDK V +WN + Sbjct: 428 LASASFDSTVRLWDVERGVCIHT-LTKHQEPVYSVAFSPDGKYLASGSFDKCVHIWNTQS 486 Query: 193 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIR 315 G V ++RG ++++ W+A + + + D ++ V D+R Sbjct: 487 GSLVHSYRG-TGGIFEVCWNARGDKVGASASDGSVCVLDLR 526 Score = 60.8 bits (146), Expect = 3e-09 Identities = 40/149 (26%), Positives = 62/149 (41%), Gaps = 9/149 (6%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 ++S D T +W+ + K + H V + + AS S D + + Sbjct: 294 ILSAGVDKTTIIWDAHTG-EAKQQFPFHSAPALDVDWQ-NNTTFASCSTDMCIHVCRLGC 351 Query: 193 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVD 372 + V F+GH +V I W LL S S D TLK+W ++ DL H+ E+Y + Sbjct: 352 DRPVKTFQGHTNEVNAIKWDPSGMLLASCSDDMTLKIWSMKQDACVHDLQAHSKEIYTIK 411 Query: 373 WSPDGE---------KVVSGGKDRALKLW 432 WSP G + S D ++LW Sbjct: 412 WSPTGPATSNPNSNIMLASASFDSTVRLW 440 Score = 56.6 bits (135), Expect = 6e-08 Identities = 44/194 (22%), Positives = 66/194 (34%), Gaps = 54/194 (27%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKA---------RMTGHQ----KVVNHVYFSPDGQWLASA 153 L SGS D T +W + + R GH K V + ++ DG LA+ Sbjct: 197 LASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDVPSNKDVTSLDWNSDGTLLATG 256 Query: 154 SFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQ 333 S+D ++W G + H ++ + W+ +LS D T +WD + KQ Sbjct: 257 SYDGFARIWTE-DGNLASTLGQHKGPIFALKWNKKGNYILSAGVDKTTIIWDAHTGEAKQ 315 Query: 334 DLP-----------------------------------------GHADEVYAVDWSPDGE 390 P GH +EV A+ W P G Sbjct: 316 QFPFHSAPALDVDWQNNTTFASCSTDMCIHVCRLGCDRPVKTFQGHTNEVNAIKWDPSGM 375 Query: 391 KVVSGGKDRALKLW 432 + S D LK+W Sbjct: 376 LLASCSDDMTLKIW 389 Score = 53.1 bits (126), Expect = 6e-07 Identities = 35/130 (26%), Positives = 58/130 (44%), Gaps = 14/130 (10%) Frame = +1 Query: 85 MTGHQKVVNHVYFSPDGQWLASASFDKSVKLW------NGITGKFVTAF----RGHVA-- 228 + GH+ V ++P LAS S D + ++W NG + + V GH Sbjct: 178 LRGHESEVFICAWNPVSDLLASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDVPS 237 Query: 229 --DVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVS 402 DV + W++D LL +GS D ++W L L H ++A+ W+ G ++S Sbjct: 238 NKDVTSLDWNSDGTLLATGSYDGFARIW-TEDGNLASTLGQHKGPIFALKWNKKGNYILS 296 Query: 403 GGKDRALKLW 432 G D+ +W Sbjct: 297 AGVDKTTIIW 306 Score = 52.4 bits (124), Expect = 1e-06 Identities = 28/91 (30%), Positives = 47/91 (51%), Gaps = 15/91 (16%) Frame = +1 Query: 205 TAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIR---------------ARKLKQDL 339 T RGH ++V+ +W+ S LL SGS DST ++W++ R+ D+ Sbjct: 176 TVLRGHESEVFICAWNPVSDLLASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDV 235 Query: 340 PGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 P + D V ++DW+ DG + +G D ++W Sbjct: 236 PSNKD-VTSLDWNSDGTLLATGSYDGFARIW 265
>PF20_CHLRE (P93107) Flagellar WD-repeat protein PF20| Length = 606 Score = 77.8 bits (190), Expect = 2e-14 Identities = 48/141 (34%), Positives = 69/141 (48%), Gaps = 1/141 (0%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQP-KARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGI 189 L SG D + +W+ KQ T H++ + V F G+ +AS S D +V+LW+ Sbjct: 383 LASGGGDSAVKIWD--FEKQRCVTTFTDHKQAIWSVRFHHLGEVVASGSLDHTVRLWDLP 440 Query: 190 TGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAV 369 GK A RGHV V ++W S L + S D T+ VWD RA Q GH + V Sbjct: 441 AGKCRMALRGHVDSVNDLAWQPFSSSLATASSDKTVSVWDARAGLCTQTYYGHQNSCNGV 500 Query: 370 DWSPDGEKVVSGGKDRALKLW 432 ++ G ++ S D +KLW Sbjct: 501 SFNILGTQLASTDADGVVKLW 521 Score = 77.8 bits (190), Expect = 2e-14 Identities = 44/144 (30%), Positives = 69/144 (47%), Gaps = 4/144 (2%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMT----GHQKVVNHVYFSPDGQWLASASFDKSVKLW 180 LV+ SDD T +W P + GH+ V V F P G LAS D +VK+W Sbjct: 341 LVTASDDKTWKMWH-----MPGGDLIMCGEGHKDWVAGVDFHPAGTCLASGGGDSAVKIW 395 Query: 181 NGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEV 360 + + VT F H ++ + + ++ SGS D T+++WD+ A K + L GH D V Sbjct: 396 DFEKQRCVTTFTDHKQAIWSVRFHHLGEVVASGSLDHTVRLWDLPAGKCRMALRGHVDSV 455 Query: 361 YAVDWSPDGEKVVSGGKDRALKLW 432 + W P + + D+ + +W Sbjct: 456 NDLAWQPFSSSLATASSDKTVSVW 479 Score = 64.3 bits (155), Expect = 3e-10 Identities = 51/182 (28%), Positives = 73/182 (40%), Gaps = 42/182 (23%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 + SGS D T+ LW+ K A + GH VN + + P LA+AS DK+V +W+ Sbjct: 425 VASGSLDHTVRLWDLPAGKCRMA-LRGHVDSVNDLAWQPFSSSLATASSDKTVSVWDARA 483 Query: 193 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIR--------------ARK-- 324 G + GH +S++ L S D +K+WD R A K Sbjct: 484 GLCTQTYYGHQNSCNGVSFNILGTQLASTDADGVVKLWDTRMTAEVATINTGKHPANKSC 543 Query: 325 --------------------------LKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALK 426 L+ +L GH D V AV + P G+ +VS G D + Sbjct: 544 FDRSGQVLAVACDDGKVKAYSTTDGVLQAELAGHEDAVQAVLFDPAGQYLVSCGSDNTFR 603 Query: 427 LW 432 LW Sbjct: 604 LW 605 Score = 59.3 bits (142), Expect = 9e-09 Identities = 33/114 (28%), Positives = 52/114 (45%) Frame = +1 Query: 91 GHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLL 270 GH V ++ P L +AS DK+ K+W+ G + GH V + + L Sbjct: 324 GHLLSVANLALHPTKPILVTASDDKTWKMWHMPGGDLIMCGEGHKDWVAGVDFHPAGTCL 383 Query: 271 LSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 SG DS +K+WD ++ H +++V + GE V SG D ++LW Sbjct: 384 ASGGGDSAVKIWDFEKQRCVTTFTDHKQAIWSVRFHHLGEVVASGSLDHTVRLW 437 Score = 52.0 bits (123), Expect = 1e-06 Identities = 26/74 (35%), Positives = 39/74 (52%) Frame = +1 Query: 211 FRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGE 390 F+GH+ V ++ +L++ S D T K+W + L GH D V VD+ P G Sbjct: 322 FKGHLLSVANLALHPTKPILVTASDDKTWKMWHMPGGDLIMCGEGHKDWVAGVDFHPAGT 381 Query: 391 KVVSGGKDRALKLW 432 + SGG D A+K+W Sbjct: 382 CLASGGGDSAVKIW 395 Score = 35.8 bits (81), Expect = 0.10 Identities = 14/36 (38%), Positives = 21/36 (58%) Frame = +1 Query: 76 KARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWN 183 +A + GH+ V V F P GQ+L S D + +LW+ Sbjct: 571 QAELAGHEDAVQAVLFDPAGQYLVSCGSDNTFRLWS 606
>TBL1X_HUMAN (O60907) F-box-like/WD-repeat protein TBL1X (Transducin beta-like| 1X protein) (Transducin-beta-like 1, X-linked) (SMAP55) Length = 526 Score = 77.4 bits (189), Expect = 3e-14 Identities = 41/130 (31%), Positives = 65/130 (50%), Gaps = 9/130 (6%) Frame = +1 Query: 70 QPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISW 249 +P GH VN + + P G LAS S D ++K+W+ + + H ++Y I W Sbjct: 352 RPVKTFQGHTNEVNAIKWDPSGMLLASCSDDMTLKIWSMKQEVCIHDLQAHNKEIYTIKW 411 Query: 250 SA---------DSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVS 402 S + +L S S DST+++WDI L H + VY+V +SPDG+ + S Sbjct: 412 SPTGPATSNPNSNIMLASASFDSTVRLWDIERGVCTHTLTKHQEPVYSVAFSPDGKYLAS 471 Query: 403 GGKDRALKLW 432 G D+ + +W Sbjct: 472 GSFDKCVHIW 481 Score = 65.5 bits (158), Expect = 1e-10 Identities = 37/101 (36%), Positives = 58/101 (57%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 L S S D T+ LW+ +T HQ+ V V FSPDG++LAS SFDK V +WN + Sbjct: 427 LASASFDSTVRLWDIERGVCTHT-LTKHQEPVYSVAFSPDGKYLASGSFDKCVHIWNTQS 485 Query: 193 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIR 315 G V ++RG ++++ W+A + + + D ++ V D+R Sbjct: 486 GNLVHSYRG-TGGIFEVCWNARGDKVGASASDGSVCVLDLR 525 Score = 64.3 bits (155), Expect = 3e-10 Identities = 44/145 (30%), Positives = 67/145 (46%), Gaps = 11/145 (7%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKA--RMTGHQKVVNHVYFSPDGQ---------WLASASF 159 L S SDD T+ +W KQ + H K + + +SP G LASASF Sbjct: 376 LASCSDDMTLKIWS---MKQEVCIHDLQAHNKEIYTIKWSPTGPATSNPNSNIMLASASF 432 Query: 160 DKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDL 339 D +V+LW+ G H VY +++S D + L SGS D + +W+ ++ L Sbjct: 433 DSTVRLWDIERGVCTHTLTKHQEPVYSVAFSPDGKYLASGSFDKCVHIWNTQSGNLVHSY 492 Query: 340 PGHADEVYAVDWSPDGEKVVSGGKD 414 G ++ V W+ G+KV + D Sbjct: 493 RG-TGGIFEVCWNARGDKVGASASD 516 Score = 59.7 bits (143), Expect = 7e-09 Identities = 40/149 (26%), Positives = 61/149 (40%), Gaps = 9/149 (6%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 ++S D T +W+ + K + H V + + AS S D + + Sbjct: 293 ILSAGVDKTTIIWDAHTG-EAKQQFPFHSAPALDVDWQ-NNTTFASCSTDMCIHVCRLGC 350 Query: 193 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVD 372 + V F+GH +V I W LL S S D TLK+W ++ DL H E+Y + Sbjct: 351 DRPVKTFQGHTNEVNAIKWDPSGMLLASCSDDMTLKIWSMKQEVCIHDLQAHNKEIYTIK 410 Query: 373 WSPDGE---------KVVSGGKDRALKLW 432 WSP G + S D ++LW Sbjct: 411 WSPTGPATSNPNSNIMLASASFDSTVRLW 439 Score = 54.7 bits (130), Expect = 2e-07 Identities = 43/194 (22%), Positives = 66/194 (34%), Gaps = 54/194 (27%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKA---------RMTGHQ----KVVNHVYFSPDGQWLASA 153 L SGS D T +W + + R GH K V + ++ +G LA+ Sbjct: 196 LASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDVPSNKDVTSLDWNTNGTLLATG 255 Query: 154 SFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQ 333 S+D ++W G + H ++ + W+ +LS D T +WD + KQ Sbjct: 256 SYDGFARIWTE-DGNLASTLGQHKGPIFALKWNRKGNYILSAGVDKTTIIWDAHTGEAKQ 314 Query: 334 DLP-----------------------------------------GHADEVYAVDWSPDGE 390 P GH +EV A+ W P G Sbjct: 315 QFPFHSAPALDVDWQNNTTFASCSTDMCIHVCRLGCDRPVKTFQGHTNEVNAIKWDPSGM 374 Query: 391 KVVSGGKDRALKLW 432 + S D LK+W Sbjct: 375 LLASCSDDMTLKIW 388 Score = 50.4 bits (119), Expect = 4e-06 Identities = 34/130 (26%), Positives = 57/130 (43%), Gaps = 14/130 (10%) Frame = +1 Query: 85 MTGHQKVVNHVYFSPDGQWLASASFDKSVKLW------NGITGKFVTAF----RGHVA-- 228 + GH+ V ++P LAS S D + ++W NG + + V GH Sbjct: 177 LRGHESEVFICAWNPVSDLLASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDVPS 236 Query: 229 --DVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVS 402 DV + W+ + LL +GS D ++W L L H ++A+ W+ G ++S Sbjct: 237 NKDVTSLDWNTNGTLLATGSYDGFARIW-TEDGNLASTLGQHKGPIFALKWNRKGNYILS 295 Query: 403 GGKDRALKLW 432 G D+ +W Sbjct: 296 AGVDKTTIIW 305 Score = 50.4 bits (119), Expect = 4e-06 Identities = 27/91 (29%), Positives = 47/91 (51%), Gaps = 15/91 (16%) Frame = +1 Query: 205 TAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIR---------------ARKLKQDL 339 T RGH ++V+ +W+ S LL SGS DST ++W++ R+ D+ Sbjct: 175 TVLRGHESEVFICAWNPVSDLLASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDV 234 Query: 340 PGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 P + D V ++DW+ +G + +G D ++W Sbjct: 235 PSNKD-VTSLDWNTNGTLLATGSYDGFARIW 264
>PRP46_YEAST (Q12417) Pre-mRNA-splicing factor PRP46 (Pre-mRNA-processing| protein 46) (Complexed with CEF1 protein 1) (PRP19-associated complex protein 50) (PRP nineteen-associated complex protein 50) Length = 451 Score = 77.4 bits (189), Expect = 3e-14 Identities = 44/139 (31%), Positives = 70/139 (50%) Frame = +1 Query: 16 VSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITG 195 ++GS+D TM +W+ K K + GH V V S +L S S DK+VK W+ Sbjct: 156 ITGSNDTTMKVWDLATGKL-KTTLAGHVMTVRDVAVSDRHPYLFSVSEDKTVKCWDLEKN 214 Query: 196 KFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDW 375 + + + GH++ V +S L+ + +DS +K+WD+R R L GH + V Sbjct: 215 QIIRDYYGHLSGVRTVSIHPTLDLIATAGRDSVIKLWDMRTRIPVITLVGHKGPINQVQC 274 Query: 376 SPDGEKVVSGGKDRALKLW 432 +P +VVS D ++LW Sbjct: 275 TPVDPQVVSSSTDATVRLW 293 Score = 73.9 bits (180), Expect = 3e-13 Identities = 39/117 (33%), Positives = 59/117 (50%), Gaps = 1/117 (0%) Frame = +1 Query: 85 MTGHQKVVNHVYFSP-DGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADS 261 + GH V V P D +W + S D ++K+W+ TGK T GHV V ++ S Sbjct: 135 INGHLGWVRCVAIDPVDNEWFITGSNDTTMKVWDLATGKLKTTLAGHVMTVRDVAVSDRH 194 Query: 262 RLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 L S S+D T+K WD+ ++ +D GH V V P + + + G+D +KLW Sbjct: 195 PYLFSVSEDKTVKCWDLEKNQIIRDYYGHLSGVRTVSIHPTLDLIATAGRDSVIKLW 251
>WDR1_HUMAN (O75083) WD-repeat protein 1 (Actin-interacting protein 1) (AIP1)| (NORI-1) Length = 605 Score = 77.4 bits (189), Expect = 3e-14 Identities = 47/116 (40%), Positives = 61/116 (52%), Gaps = 3/116 (2%) Frame = +1 Query: 4 PXRLVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWN 183 P RL +GSDD +E K K + H + VN V FSPDG A+AS D + +++ Sbjct: 158 PYRLATGSDDNCAAFFEGPPFKF-KFTIGDHSRFVNCVRFSPDGNRFATASADGQIYIYD 216 Query: 184 GITGKFVTAFRG---HVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLP 342 G TG+ V A G H +Y ISWS DS LLS S D T K+WD+ + P Sbjct: 217 GKTGEKVCALGGSKAHDGGIYAISWSPDSTHLLSASGDKTSKIWDVSVNSVVSTFP 272 Score = 57.4 bits (137), Expect = 3e-08 Identities = 38/135 (28%), Positives = 59/135 (43%), Gaps = 4/135 (2%) Frame = +1 Query: 40 MFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQW-LASASFDKSVKLWNGITGKFVTAFR 216 +FLW+ S +TGH KV+N V + LA+ S D + G KF Sbjct: 129 VFLWD---SGSSVGEITGHNKVINSVDIKQSRPYRLATGSDDNCAAFFEGPPFKFKFTIG 185 Query: 217 GHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPG---HADEVYAVDWSPDG 387 H V + +S D + S D + ++D + + L G H +YA+ WSPD Sbjct: 186 DHSRFVNCVRFSPDGNRFATASADGQIYIYDGKTGEKVCALGGSKAHDGGIYAISWSPDS 245 Query: 388 EKVVSGGKDRALKLW 432 ++S D+ K+W Sbjct: 246 THLLSASGDKTSKIW 260 Score = 38.5 bits (88), Expect = 0.016 Identities = 30/112 (26%), Positives = 49/112 (43%), Gaps = 3/112 (2%) Frame = +1 Query: 106 VNHVYFSPDGQWLASASFDKSVKLWNGITGKFVT-AFRGHVADVYQISWSADSRLLLSGS 282 V V +S DG +LA K V +++ G F GH A + ++WS D+ SG Sbjct: 491 VTDVAYSHDGAFLAVCDASKVVTVFSVADGYSENNVFYGHHAKIVCLAWSPDNEHFASGG 550 Query: 283 KDSTLKVWDIR--ARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 D + VW + ++K V ++ W D +V+ D ++K W Sbjct: 551 MDMMVYVWTLSDPETRVKIQDAHRLHHVSSLAWL-DEHTLVTTSHDASVKEW 601 Score = 38.5 bits (88), Expect = 0.016 Identities = 31/109 (28%), Positives = 51/109 (46%), Gaps = 7/109 (6%) Frame = +1 Query: 127 PDGQWLASASFDKSVKLWN--GIT----GKFVTAFRGHVADVYQISWSADSRLLLSGSKD 288 P G +A D +V+L++ G T GK + A +G V DV ++S D L Sbjct: 454 PGGDTVAIGGVDGNVRLYSILGTTLKDEGKLLEA-KGPVTDV---AYSHDGAFLAVCDAS 509 Query: 289 STLKVWDIRARKLKQDL-PGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 + V+ + + ++ GH ++ + WSPD E SGG D + +W Sbjct: 510 KVVTVFSVADGYSENNVFYGHHAKIVCLAWSPDNEHFASGGMDMMVYVW 558 Score = 31.6 bits (70), Expect = 1.9 Identities = 23/78 (29%), Positives = 35/78 (44%), Gaps = 4/78 (5%) Frame = +1 Query: 91 GHQKVVNHVYFSPDGQWLASASFDKSVKLWN----GITGKFVTAFRGHVADVYQISWSAD 258 GH + + +SPD + AS D V +W K A R H V ++W D Sbjct: 529 GHHAKIVCLAWSPDNEHFASGGMDMMVYVWTLSDPETRVKIQDAHRLH--HVSSLAW-LD 585 Query: 259 SRLLLSGSKDSTLKVWDI 312 L++ S D+++K W I Sbjct: 586 EHTLVTTSHDASVKEWTI 603
>FBW1A_HUMAN (Q9Y297) F-box/WD-repeat protein 1A (F-box and WD-repeats protein| beta-TrCP) (E3RSIkappaB) (pIkappaBalpha-E3 receptor subunit) Length = 605 Score = 77.4 bits (189), Expect = 3e-14 Identities = 45/142 (31%), Positives = 79/142 (55%), Gaps = 2/142 (1%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKAR--MTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNG 186 +V+ S D ++ +W+ R + GH+ VN V F D +++ SAS D+++K+WN Sbjct: 396 MVTCSKDRSIAVWDMASPTDITLRRVLVGHRAAVNVVDF--DDKYIVSASGDRTIKVWNT 453 Query: 187 ITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYA 366 T +FV GH + + + RL++SGS D+T+++WDI + L GH + V Sbjct: 454 STCEFVRTLNGHKRGIACLQYR--DRLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRC 511 Query: 367 VDWSPDGEKVVSGGKDRALKLW 432 + + D +++VSG D +K+W Sbjct: 512 IRF--DNKRIVSGAYDGKIKVW 531 Score = 58.9 bits (141), Expect = 1e-08 Identities = 41/149 (27%), Positives = 79/149 (53%), Gaps = 3/149 (2%) Frame = +1 Query: 10 RLVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGI 189 ++VSG D T+ +W+ + + K +TGH V + + D + + + S D +V++W+ Sbjct: 315 KIVSGLRDNTIKIWDKN-TLECKRILTGHTGSVLCLQY--DERVIITGSSDSTVRVWDVN 371 Query: 190 TGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRAR---KLKQDLPGHADEV 360 TG+ + H V + ++ + ++++ SKD ++ VWD+ + L++ L GH V Sbjct: 372 TGEMLNTLIHHCEAVLHLRFN--NGMMVTCSKDRSIAVWDMASPTDITLRRVLVGHRAAV 429 Query: 361 YAVDWSPDGEKVVSGGKDRALKLWMN*AC 447 VD+ D + +VS DR +K+W C Sbjct: 430 NVVDF--DDKYIVSASGDRTIKVWNTSTC 456 Score = 53.1 bits (126), Expect = 6e-07 Identities = 28/101 (27%), Positives = 54/101 (53%) Frame = +1 Query: 130 DGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWD 309 D Q + S D ++K+W+ T + GH V + + D R++++GS DST++VWD Sbjct: 312 DDQKIVSGLRDNTIKIWDKNTLECKRILTGHTGSVLCLQY--DERVIITGSSDSTVRVWD 369 Query: 310 IRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 + ++ L H + V + + + +V+ KDR++ +W Sbjct: 370 VNTGEMLNTLIHHCEAVLHLRF--NNGMMVTCSKDRSIAVW 408
>PRP46_CRYNE (Q5KDR4) Pre-mRNA-splicing factor PRP46 (Pre-mRNA-processing| protein 46) Length = 473 Score = 77.0 bits (188), Expect = 4e-14 Identities = 41/138 (29%), Positives = 71/138 (51%) Frame = +1 Query: 19 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 198 +G+ D + +W+ S + K +TGH + + S +L S + DK VK W+ T K Sbjct: 199 TGAGDRVIKIWD-LASGELKLSLTGHISTIRGLAVSDRHPYLFSCAEDKMVKCWDLETNK 257 Query: 199 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWS 378 + + GH + VY +S +L++G +D++++VWD+R R L GH V V Sbjct: 258 VIRHYHGHFSGVYSLSVHPTLDVLVTGGRDASVRVWDMRTRANIFTLTGHTSTVGDVKTQ 317 Query: 379 PDGEKVVSGGKDRALKLW 432 +++SG D ++LW Sbjct: 318 DSDPQIISGSMDSTVRLW 335 Score = 73.2 bits (178), Expect = 6e-13 Identities = 32/116 (27%), Positives = 64/116 (55%) Frame = +1 Query: 85 MTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSR 264 ++GH V V P QW A+ + D+ +K+W+ +G+ + GH++ + ++ S Sbjct: 178 ISGHMGWVRAVAMDPGNQWFATGAGDRVIKIWDLASGELKLSLTGHISTIRGLAVSDRHP 237 Query: 265 LLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 L S ++D +K WD+ K+ + GH VY++ P + +V+GG+D ++++W Sbjct: 238 YLFSCAEDKMVKCWDLETNKVIRHYHGHFSGVYSLSVHPTLDVLVTGGRDASVRVW 293 Score = 61.6 bits (148), Expect = 2e-09 Identities = 45/150 (30%), Positives = 76/150 (50%), Gaps = 9/150 (6%) Frame = +1 Query: 10 RLVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFD-KSVKLWNG 186 +++SGS D T+ LW+ K +T H+K V + P ASAS ++K W Sbjct: 322 QIISGSMDSTVRLWDLAAGKCMNT-LTHHKKSVRALAIHPTEYSFASASSGGNNIKKWKC 380 Query: 187 ITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDL-----PGHA 351 G FV F GH A + +S ++++ +L SG+ + TL +WD + Q L PG Sbjct: 381 PEGIFVNNFVGHEAIINTLSINSEN-VLFSGADNGTLTLWDYKTGLPFQHLKDIPQPGSL 439 Query: 352 DE---VYAVDWSPDGEKVVSGGKDRALKLW 432 D V+ + G ++++GG D+ +K++ Sbjct: 440 DAEAGVFCSTFDKTGTRLITGGADKTIKVY 469 Score = 40.8 bits (94), Expect = 0.003 Identities = 19/79 (24%), Positives = 37/79 (46%) Frame = +1 Query: 196 KFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDW 375 K GH+ V ++ ++ +G+ D +K+WD+ + +LK L GH + + Sbjct: 173 KLTRVISGHMGWVRAVAMDPGNQWFATGAGDRVIKIWDLASGELKLSLTGHISTIRGLAV 232 Query: 376 SPDGEKVVSGGKDRALKLW 432 S + S +D+ +K W Sbjct: 233 SDRHPYLFSCAEDKMVKCW 251
>WDR57_MOUSE (Q6PE01) WD-repeat protein 57| Length = 358 Score = 77.0 bits (188), Expect = 4e-14 Identities = 45/141 (31%), Positives = 73/141 (51%), Gaps = 1/141 (0%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 L S D + LW A + GH V ++++ DG L SAS DK+V +W+ T Sbjct: 82 LASAGFDRLILLWNVYGDCDNYATLKGHSGAVMELHYNTDGSMLFSASTDKTVAVWDSET 141 Query: 193 GKFVTAFRGHVADVYQ-ISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAV 369 G+ V +GH + V +L+ +GS D T+K+WDIR + Q + +V AV Sbjct: 142 GERVKRLKGHTSFVNSCYPARRGPQLVCTGSDDGTVKLWDIRKKAAVQTFQ-NTYQVLAV 200 Query: 370 DWSPDGEKVVSGGKDRALKLW 432 ++ ++++SGG D +K+W Sbjct: 201 TFNDTSDQIISGGIDNDIKVW 221 Score = 76.3 bits (186), Expect = 7e-14 Identities = 44/151 (29%), Positives = 72/151 (47%), Gaps = 8/151 (5%) Frame = +1 Query: 4 PXRLVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWN 183 P + +GSDD T+ LW+ I K+ + + V V F+ + S D +K+W+ Sbjct: 165 PQLVCTGSDDGTVKLWD--IRKKAAVQTFQNTYQVLAVTFNDTSDQIISGGIDNDIKVWD 222 Query: 184 GITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQ--------DL 339 K RGH V +S S++ LLS + D+T++VWD+R K+ ++ Sbjct: 223 LRQNKLTYTMRGHADSVTGLSLSSEGSYLLSNAMDNTVRVWDVRPFAPKERCVKIFQGNV 282 Query: 340 PGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 + WSPDG K+ +G DR + +W Sbjct: 283 HNFEKNLLRCSWSPDGSKIAAGSADRFVYVW 313 Score = 75.1 bits (183), Expect = 2e-13 Identities = 45/141 (31%), Positives = 75/141 (53%), Gaps = 1/141 (0%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDG-QWLASASFDKSVKLWNGI 189 L S S D T+ +W+ ++ K R+ GH VN Y + G Q + + S D +VKLW+ Sbjct: 125 LFSASTDKTVAVWDSETGERVK-RLKGHTSFVNSCYPARRGPQLVCTGSDDGTVKLWDIR 183 Query: 190 TGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAV 369 V F+ + V ++++ S ++SG D+ +KVWD+R KL + GHAD V + Sbjct: 184 KKAAVQTFQ-NTYQVLAVTFNDTSDQIISGGIDNDIKVWDLRQNKLTYTMRGHADSVTGL 242 Query: 370 DWSPDGEKVVSGGKDRALKLW 432 S +G ++S D +++W Sbjct: 243 SLSSEGSYLLSNAMDNTVRVW 263 Score = 68.9 bits (167), Expect = 1e-11 Identities = 42/146 (28%), Positives = 74/146 (50%), Gaps = 8/146 (5%) Frame = +1 Query: 10 RLVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWN-- 183 +++SG D + +W+ +K M GH V + S +G +L S + D +V++W+ Sbjct: 208 QIISGGIDNDIKVWDLRQNKLTYT-MRGHADSVTGLSLSSEGSYLLSNAMDNTVRVWDVR 266 Query: 184 --GITGKFVTAFRGHV----ADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPG 345 + V F+G+V ++ + SWS D + +GS D + VWD +R++ LPG Sbjct: 267 PFAPKERCVKIFQGNVHNFEKNLLRCSWSPDGSKIAAGSADRFVYVWDTTSRRVLYKLPG 326 Query: 346 HADEVYAVDWSPDGEKVVSGGKDRAL 423 HA + V + PD ++S D+ L Sbjct: 327 HAGSINEVAFHPDEPIILSASSDKRL 352 Score = 67.0 bits (162), Expect = 4e-11 Identities = 41/123 (33%), Positives = 63/123 (51%), Gaps = 3/123 (2%) Frame = +1 Query: 73 PKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWN--GITGKFVTAFRGHVADVYQIS 246 P ++GH+ V F P+G LASA FD+ + LWN G + T +GH V ++ Sbjct: 59 PIMLLSGHEGEVYCCKFHPNGSTLASAGFDRLILLWNVYGDCDNYAT-LKGHSGAVMELH 117 Query: 247 WSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVV-SGGKDRAL 423 ++ D +L S S D T+ VWD + + L GH V + + G ++V +G D + Sbjct: 118 YNTDGSMLFSASTDKTVAVWDSETGERVKRLKGHTSFVNSCYPARRGPQLVCTGSDDGTV 177 Query: 424 KLW 432 KLW Sbjct: 178 KLW 180 Score = 43.5 bits (101), Expect = 5e-04 Identities = 26/108 (24%), Positives = 55/108 (50%), Gaps = 7/108 (6%) Frame = +1 Query: 13 LVSGSDDFTMFLWE--PTISKQP-----KARMTGHQKVVNHVYFSPDGQWLASASFDKSV 171 L+S + D T+ +W+ P K+ + + +K + +SPDG +A+ S D+ V Sbjct: 251 LLSNAMDNTVRVWDVRPFAPKERCVKIFQGNVHNFEKNLLRCSWSPDGSKIAAGSADRFV 310 Query: 172 KLWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIR 315 +W+ + + + GH + ++++ D ++LS S D L + +I+ Sbjct: 311 YVWDTTSRRVLYKLPGHAGSINEVAFHPDEPIILSASSDKRLYMGEIQ 358
>PRP46_EMENI (Q5BE22) Pre-mRNA-splicing factor prp46 (Pre-mRNA-processing| protein 46) Length = 452 Score = 77.0 bits (188), Expect = 4e-14 Identities = 43/138 (31%), Positives = 67/138 (48%) Frame = +1 Query: 19 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 198 SG+ D T+ +W + +TGH V + SP +L S DK VK W+ T K Sbjct: 160 SGAGDRTIKIWNLATGAL-RLTLTGHISTVRGLAVSPRHPYLFSCGEDKMVKCWDLETNK 218 Query: 199 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWS 378 + + GH++ VY ++ LL++G +D +VWD+R R L GH V V Sbjct: 219 VIRHYHGHLSGVYTLALHPRLDLLVTGGRDGVARVWDMRTRSNIHVLSGHTGTVADVQCQ 278 Query: 379 PDGEKVVSGGKDRALKLW 432 +V++G D ++LW Sbjct: 279 EADPQVITGSLDATVRLW 296 Score = 74.3 bits (181), Expect = 3e-13 Identities = 39/148 (26%), Positives = 70/148 (47%), Gaps = 10/148 (6%) Frame = +1 Query: 19 SGSDDFTMFLWEPTISKQPKAR----------MTGHQKVVNHVYFSPDGQWLASASFDKS 168 +G D T + P+ ++Q ++GH V + P+ +W AS + D++ Sbjct: 107 AGDDKPTSLIQRPSATRQQPPEWHAPWKLMRVISGHLGWVRSLAVEPNNEWFASGAGDRT 166 Query: 169 VKLWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGH 348 +K+WN TG GH++ V ++ S L S +D +K WD+ K+ + GH Sbjct: 167 IKIWNLATGALRLTLTGHISTVRGLAVSPRHPYLFSCGEDKMVKCWDLETNKVIRHYHGH 226 Query: 349 ADEVYAVDWSPDGEKVVSGGKDRALKLW 432 VY + P + +V+GG+D ++W Sbjct: 227 LSGVYTLALHPRLDLLVTGGRDGVARVW 254 Score = 52.4 bits (124), Expect = 1e-06 Identities = 40/152 (26%), Positives = 73/152 (48%), Gaps = 8/152 (5%) Frame = +1 Query: 1 APXRLVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLW 180 A ++++GS D T+ LW+ K +T H+K + + P ASAS S+K W Sbjct: 280 ADPQVITGSLDATVRLWDLAAGKTMGV-LTHHKKGIRSLATHPREFTFASASTG-SIKQW 337 Query: 181 NGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDL-----PG 345 G+F+ F GH A + +S + D+ +L SG + ++ WD + Q + PG Sbjct: 338 KCPGGEFMQNFEGHNAIINTLSVNEDN-VLFSGGDNGSMSFWDWKTGYRYQTIDTTAQPG 396 Query: 346 HADE---VYAVDWSPDGEKVVSGGKDRALKLW 432 + + + G ++++G D+ +K+W Sbjct: 397 SLEAEAGIMTSTFDRTGLRLITGEADKTIKVW 428
>WDR57_PONPY (Q5RF51) WD-repeat protein 57| Length = 357 Score = 76.6 bits (187), Expect = 5e-14 Identities = 44/151 (29%), Positives = 73/151 (48%), Gaps = 8/151 (5%) Frame = +1 Query: 4 PXRLVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWN 183 P + +GSDD T+ LW+ I K+ + + V V F+ + S D +K+W+ Sbjct: 164 PQLVCTGSDDGTVKLWD--IRKKAAIQTFQNTYQVLAVTFNDTSDQIISGGIDNDIKVWD 221 Query: 184 GITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQ--------DL 339 K RGH V +S S++ LLS + D+T++VWD+R K+ ++ Sbjct: 222 LRQNKLTYTMRGHADSVTGLSLSSEGSYLLSNAMDNTVRVWDVRPFAPKERCVKIFQGNV 281 Query: 340 PGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 + WSPDG K+ +G DR++ +W Sbjct: 282 HNFEKNLLRCSWSPDGSKIAAGSADRSVCVW 312 Score = 74.7 bits (182), Expect = 2e-13 Identities = 44/141 (31%), Positives = 75/141 (53%), Gaps = 1/141 (0%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDG-QWLASASFDKSVKLWNGI 189 L S S D T+ +W+ ++ K R+ GH VN Y + G Q + + S D +VKLW+ Sbjct: 124 LFSASTDKTVAVWDSETGERVK-RLKGHTSFVNSCYPARRGPQLVCTGSDDGTVKLWDIR 182 Query: 190 TGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAV 369 + F+ + V ++++ S ++SG D+ +KVWD+R KL + GHAD V + Sbjct: 183 KKAAIQTFQ-NTYQVLAVTFNDTSDQIISGGIDNDIKVWDLRQNKLTYTMRGHADSVTGL 241 Query: 370 DWSPDGEKVVSGGKDRALKLW 432 S +G ++S D +++W Sbjct: 242 SLSSEGSYLLSNAMDNTVRVW 262 Score = 73.6 bits (179), Expect = 4e-13 Identities = 44/141 (31%), Positives = 73/141 (51%), Gaps = 1/141 (0%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 L S D + LW A + G+ V ++++ DG L SAS DK+V +W+ T Sbjct: 81 LASAGFDRLILLWNVYGDCGNYATLKGYSGAVMELHYNTDGSMLFSASTDKTVAVWDSET 140 Query: 193 GKFVTAFRGHVADVYQ-ISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAV 369 G+ V +GH + V +L+ +GS D T+K+WDIR + Q + +V AV Sbjct: 141 GERVKRLKGHTSFVNSCYPARRGPQLVCTGSDDGTVKLWDIRKKAAIQTFQ-NTYQVLAV 199 Query: 370 DWSPDGEKVVSGGKDRALKLW 432 ++ ++++SGG D +K+W Sbjct: 200 TFNDTSDQIISGGIDNDIKVW 220 Score = 70.9 bits (172), Expect = 3e-12 Identities = 42/146 (28%), Positives = 75/146 (51%), Gaps = 8/146 (5%) Frame = +1 Query: 10 RLVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWN-- 183 +++SG D + +W+ +K M GH V + S +G +L S + D +V++W+ Sbjct: 207 QIISGGIDNDIKVWDLRQNKLTYT-MRGHADSVTGLSLSSEGSYLLSNAMDNTVRVWDVR 265 Query: 184 --GITGKFVTAFRGHV----ADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPG 345 + V F+G+V ++ + SWS D + +GS D ++ VWD +R++ LPG Sbjct: 266 PFAPKERCVKIFQGNVHNFEKNLLRCSWSPDGSKIAAGSADRSVCVWDTTSRRILYKLPG 325 Query: 346 HADEVYAVDWSPDGEKVVSGGKDRAL 423 HA + V + PD ++S D+ L Sbjct: 326 HAGSINEVAFHPDEPIIISASSDKRL 351 Score = 67.4 bits (163), Expect = 3e-11 Identities = 41/123 (33%), Positives = 64/123 (52%), Gaps = 3/123 (2%) Frame = +1 Query: 73 PKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWN--GITGKFVTAFRGHVADVYQIS 246 P ++GH+ V F P+G LASA FD+ + LWN G G + T +G+ V ++ Sbjct: 58 PIMLLSGHEGEVYCCKFHPNGSTLASAGFDRLILLWNVYGDCGNYAT-LKGYSGAVMELH 116 Query: 247 WSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVV-SGGKDRAL 423 ++ D +L S S D T+ VWD + + L GH V + + G ++V +G D + Sbjct: 117 YNTDGSMLFSASTDKTVAVWDSETGERVKRLKGHTSFVNSCYPARRGPQLVCTGSDDGTV 176 Query: 424 KLW 432 KLW Sbjct: 177 KLW 179 Score = 45.1 bits (105), Expect = 2e-04 Identities = 26/108 (24%), Positives = 56/108 (51%), Gaps = 7/108 (6%) Frame = +1 Query: 13 LVSGSDDFTMFLWE--PTISKQP-----KARMTGHQKVVNHVYFSPDGQWLASASFDKSV 171 L+S + D T+ +W+ P K+ + + +K + +SPDG +A+ S D+SV Sbjct: 250 LLSNAMDNTVRVWDVRPFAPKERCVKIFQGNVHNFEKNLLRCSWSPDGSKIAAGSADRSV 309 Query: 172 KLWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIR 315 +W+ + + + GH + ++++ D +++S S D L + +I+ Sbjct: 310 CVWDTTSRRILYKLPGHAGSINEVAFHPDEPIIISASSDKRLYMGEIQ 357
>WDR57_HUMAN (Q96DI7) WD-repeat protein 57 (Prp8-binding protein) (hPRP8BP) (U5| snRNP-specific 40 kDa protein) (38 kDa splicing factor) Length = 357 Score = 76.6 bits (187), Expect = 5e-14 Identities = 45/141 (31%), Positives = 73/141 (51%), Gaps = 1/141 (0%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 L S D + LW A + GH V ++++ DG L SAS DK+V +W+ T Sbjct: 81 LASAGFDRLILLWNVYGDCDNYATLKGHSGAVMELHYNTDGSMLFSASTDKTVAVWDSET 140 Query: 193 GKFVTAFRGHVADVYQ-ISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAV 369 G+ V +GH + V +L+ +GS D T+K+WDIR + Q + +V AV Sbjct: 141 GERVKRLKGHTSFVNSCYPARRGPQLVCTGSDDGTVKLWDIRKKAAIQTFQ-NTYQVLAV 199 Query: 370 DWSPDGEKVVSGGKDRALKLW 432 ++ ++++SGG D +K+W Sbjct: 200 TFNDTSDQIISGGIDNDIKVW 220 Score = 75.9 bits (185), Expect = 9e-14 Identities = 44/151 (29%), Positives = 72/151 (47%), Gaps = 8/151 (5%) Frame = +1 Query: 4 PXRLVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWN 183 P + +GSDD T+ LW+ I K+ + + V V F+ + S D +K+W+ Sbjct: 164 PQLVCTGSDDGTVKLWD--IRKKAAIQTFQNTYQVLAVTFNDTSDQIISGGIDNDIKVWD 221 Query: 184 GITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQ--------DL 339 K RGH V +S S++ LLS + D+T++VWD+R K+ ++ Sbjct: 222 LRQNKLTYTMRGHADSVTGLSLSSEGSYLLSNAMDNTVRVWDVRPFAPKERCVKIFQGNV 281 Query: 340 PGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 + WSPDG K+ +G DR + +W Sbjct: 282 HNFEKNLLRCSWSPDGSKIAAGSADRFVYVW 312 Score = 74.7 bits (182), Expect = 2e-13 Identities = 44/141 (31%), Positives = 75/141 (53%), Gaps = 1/141 (0%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDG-QWLASASFDKSVKLWNGI 189 L S S D T+ +W+ ++ K R+ GH VN Y + G Q + + S D +VKLW+ Sbjct: 124 LFSASTDKTVAVWDSETGERVK-RLKGHTSFVNSCYPARRGPQLVCTGSDDGTVKLWDIR 182 Query: 190 TGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAV 369 + F+ + V ++++ S ++SG D+ +KVWD+R KL + GHAD V + Sbjct: 183 KKAAIQTFQ-NTYQVLAVTFNDTSDQIISGGIDNDIKVWDLRQNKLTYTMRGHADSVTGL 241 Query: 370 DWSPDGEKVVSGGKDRALKLW 432 S +G ++S D +++W Sbjct: 242 SLSSEGSYLLSNAMDNTVRVW 262 Score = 70.1 bits (170), Expect = 5e-12 Identities = 42/146 (28%), Positives = 74/146 (50%), Gaps = 8/146 (5%) Frame = +1 Query: 10 RLVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWN-- 183 +++SG D + +W+ +K M GH V + S +G +L S + D +V++W+ Sbjct: 207 QIISGGIDNDIKVWDLRQNKLTYT-MRGHADSVTGLSLSSEGSYLLSNAMDNTVRVWDVR 265 Query: 184 --GITGKFVTAFRGHV----ADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPG 345 + V F+G+V ++ + SWS D + +GS D + VWD +R++ LPG Sbjct: 266 PFAPKERCVKIFQGNVHNFEKNLLRCSWSPDGSKIAAGSADRFVYVWDTTSRRILYKLPG 325 Query: 346 HADEVYAVDWSPDGEKVVSGGKDRAL 423 HA + V + PD ++S D+ L Sbjct: 326 HAGSINEVAFHPDEPIIISASSDKRL 351 Score = 67.0 bits (162), Expect = 4e-11 Identities = 41/123 (33%), Positives = 63/123 (51%), Gaps = 3/123 (2%) Frame = +1 Query: 73 PKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWN--GITGKFVTAFRGHVADVYQIS 246 P ++GH+ V F P+G LASA FD+ + LWN G + T +GH V ++ Sbjct: 58 PIMLLSGHEGEVYCCKFHPNGSTLASAGFDRLILLWNVYGDCDNYAT-LKGHSGAVMELH 116 Query: 247 WSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVV-SGGKDRAL 423 ++ D +L S S D T+ VWD + + L GH V + + G ++V +G D + Sbjct: 117 YNTDGSMLFSASTDKTVAVWDSETGERVKRLKGHTSFVNSCYPARRGPQLVCTGSDDGTV 176 Query: 424 KLW 432 KLW Sbjct: 177 KLW 179 Score = 43.1 bits (100), Expect = 6e-04 Identities = 25/108 (23%), Positives = 55/108 (50%), Gaps = 7/108 (6%) Frame = +1 Query: 13 LVSGSDDFTMFLWE--PTISKQP-----KARMTGHQKVVNHVYFSPDGQWLASASFDKSV 171 L+S + D T+ +W+ P K+ + + +K + +SPDG +A+ S D+ V Sbjct: 250 LLSNAMDNTVRVWDVRPFAPKERCVKIFQGNVHNFEKNLLRCSWSPDGSKIAAGSADRFV 309 Query: 172 KLWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIR 315 +W+ + + + GH + ++++ D +++S S D L + +I+ Sbjct: 310 YVWDTTSRRILYKLPGHAGSINEVAFHPDEPIIISASSDKRLYMGEIQ 357
>WDR1_MOUSE (O88342) WD-repeat protein 1 (Actin-interacting protein 1) (AIP1)| Length = 605 Score = 76.6 bits (187), Expect = 5e-14 Identities = 46/116 (39%), Positives = 61/116 (52%), Gaps = 3/116 (2%) Frame = +1 Query: 4 PXRLVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWN 183 P RL +GSDD +E K K + H + VN V FSPDG A+AS D + +++ Sbjct: 158 PYRLATGSDDNCAAFFEGPPFKF-KFTIGDHSRFVNCVRFSPDGNRFATASADGQIFIYD 216 Query: 184 GITGKFVTAF---RGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLP 342 G TG+ V A + H +Y ISWS DS LLS S D T K+WD+ + P Sbjct: 217 GKTGEKVCALGESKAHDGGIYAISWSPDSTHLLSASGDKTSKIWDVNVNSVVSTFP 272 Score = 53.9 bits (128), Expect = 4e-07 Identities = 37/135 (27%), Positives = 58/135 (42%), Gaps = 4/135 (2%) Frame = +1 Query: 40 MFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQW-LASASFDKSVKLWNGITGKFVTAFR 216 +FLW+ S +TGH KV+N V + LA+ S D + G KF Sbjct: 129 VFLWDTGSSV---GEITGHNKVINSVDIKQTRPYRLATGSDDNCAAFFEGPPFKFKFTIG 185 Query: 217 GHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDL---PGHADEVYAVDWSPDG 387 H V + +S D + S D + ++D + + L H +YA+ WSPD Sbjct: 186 DHSRFVNCVRFSPDGNRFATASADGQIFIYDGKTGEKVCALGESKAHDGGIYAISWSPDS 245 Query: 388 EKVVSGGKDRALKLW 432 ++S D+ K+W Sbjct: 246 THLLSASGDKTSKIW 260 Score = 39.7 bits (91), Expect = 0.007 Identities = 31/112 (27%), Positives = 49/112 (43%), Gaps = 3/112 (2%) Frame = +1 Query: 106 VNHVYFSPDGQWLASASFDKSVKLWNGITGKFVT-AFRGHVADVYQISWSADSRLLLSGS 282 V V +S DG +LA K V +++ G F GH A + ++WS D+ SG Sbjct: 491 VTDVAYSHDGAFLAVCDASKVVTVFSVADGYSENNVFYGHHAKIVCLAWSPDNEHFASGG 550 Query: 283 KDSTLKVWDIR--ARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 D + VW + K+K V ++ W D +V+ D ++K W Sbjct: 551 MDMMVYVWTLSDPETKVKIQDAHRLHHVSSLAWL-DEHTLVTTSHDASVKEW 601 Score = 36.6 bits (83), Expect = 0.059 Identities = 28/109 (25%), Positives = 50/109 (45%), Gaps = 7/109 (6%) Frame = +1 Query: 127 PDGQWLASASFDKSVKLWNGIT------GKFVTAFRGHVADVYQISWSADSRLLLSGSKD 288 P G +A D +V++++ + GK + A +G V DV ++S D L Sbjct: 454 PGGDTVAVGGTDGNVRVYSILASTLKDEGKLLEA-KGPVTDV---AYSHDGAFLAVCDAS 509 Query: 289 STLKVWDIRARKLKQDL-PGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 + V+ + + ++ GH ++ + WSPD E SGG D + +W Sbjct: 510 KVVTVFSVADGYSENNVFYGHHAKIVCLAWSPDNEHFASGGMDMMVYVW 558 Score = 31.6 bits (70), Expect = 1.9 Identities = 23/78 (29%), Positives = 35/78 (44%), Gaps = 4/78 (5%) Frame = +1 Query: 91 GHQKVVNHVYFSPDGQWLASASFDKSVKLWN----GITGKFVTAFRGHVADVYQISWSAD 258 GH + + +SPD + AS D V +W K A R H V ++W D Sbjct: 529 GHHAKIVCLAWSPDNEHFASGGMDMMVYVWTLSDPETKVKIQDAHRLH--HVSSLAW-LD 585 Query: 259 SRLLLSGSKDSTLKVWDI 312 L++ S D+++K W I Sbjct: 586 EHTLVTTSHDASVKEWTI 603
>FBW1B_HUMAN (Q9UKB1) F-box/WD-repeat protein 11 (F-box/WD-repeat protein 1B)| (F-box and WD-repeats protein beta-TrCP2) Length = 542 Score = 76.3 bits (186), Expect = 7e-14 Identities = 44/142 (30%), Positives = 80/142 (56%), Gaps = 2/142 (1%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKAR--MTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNG 186 +V+ S D ++ +W+ + R + GH+ VN V F D +++ SAS D+++K+W+ Sbjct: 333 MVTCSKDRSIAVWDMASATDITLRRVLVGHRAAVNVVDF--DDKYIVSASGDRTIKVWST 390 Query: 187 ITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYA 366 T +FV GH + + + RL++SGS D+T+++WDI + L GH + V Sbjct: 391 STCEFVRTLNGHKRGIACLQYR--DRLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRC 448 Query: 367 VDWSPDGEKVVSGGKDRALKLW 432 + + D +++VSG D +K+W Sbjct: 449 IRF--DNKRIVSGAYDGKIKVW 468 Score = 59.7 bits (143), Expect = 7e-09 Identities = 42/149 (28%), Positives = 79/149 (53%), Gaps = 3/149 (2%) Frame = +1 Query: 10 RLVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGI 189 +++SG D ++ +W+ T + K +TGH V + + D + + + S D +V++W+ Sbjct: 252 KIISGLRDNSIKIWDKTSLECLKV-LTGHTGSVLCLQY--DERVIVTGSSDSTVRVWDVN 308 Query: 190 TGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRAR---KLKQDLPGHADEV 360 TG+ + H V + +S + L+++ SKD ++ VWD+ + L++ L GH V Sbjct: 309 TGEVLNTLIHHNEAVLHLRFS--NGLMVTCSKDRSIAVWDMASATDITLRRVLVGHRAAV 366 Query: 361 YAVDWSPDGEKVVSGGKDRALKLWMN*AC 447 VD+ D + +VS DR +K+W C Sbjct: 367 NVVDF--DDKYIVSASGDRTIKVWSTSTC 393 Score = 52.8 bits (125), Expect = 8e-07 Identities = 28/101 (27%), Positives = 55/101 (54%) Frame = +1 Query: 130 DGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWD 309 D + + S D S+K+W+ + + + GH V + + D R++++GS DST++VWD Sbjct: 249 DDEKIISGLRDNSIKIWDKTSLECLKVLTGHTGSVLCLQY--DERVIVTGSSDSTVRVWD 306 Query: 310 IRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 + ++ L H + V + +S +V+ KDR++ +W Sbjct: 307 VNTGEVLNTLIHHNEAVLHLRFS--NGLMVTCSKDRSIAVW 345
>GBB1_DROME (P26308) Guanine nucleotide-binding protein beta subunit 1| Length = 340 Score = 75.9 bits (185), Expect = 9e-14 Identities = 40/116 (34%), Positives = 64/116 (55%) Frame = +1 Query: 85 MTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSR 264 + GH ++ F D Q + ++S D S LW+ TG VT+F GH DV +S + + Sbjct: 139 LPGHGGYLSCCRFLDDNQ-IVTSSGDMSCGLWDIETGLQVTSFLGHTGDVMALSLAPQCK 197 Query: 265 LLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 +SG+ D++ K+WDIR KQ PGH ++ AV + P+G+ +G D +L+ Sbjct: 198 TFVSGACDASAKLWDIREGVCKQTFPGHESDINAVTFFPNGQAFATGSDDATCRLF 253 Score = 60.5 bits (145), Expect = 4e-09 Identities = 43/144 (29%), Positives = 69/144 (47%), Gaps = 5/144 (3%) Frame = +1 Query: 16 VSGSDDFTMFLWE--PTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGI 189 VSG+ D + LW+ + KQ GH+ +N V F P+GQ A+ S D + +L++ I Sbjct: 200 VSGACDASAKLWDIREGVCKQT---FPGHESDINAVTFFPNGQAFATGSDDATCRLFD-I 255 Query: 190 TGKFVTAFRGH---VADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEV 360 A H + + +++S RLLL+G D VWD + L GH + V Sbjct: 256 RADQELAMYSHDNIICGITSVAFSKSGRLLLAGYDDFNCNVWDTMKAERSGILAGHDNRV 315 Query: 361 YAVDWSPDGEKVVSGGKDRALKLW 432 + + +G V +G D L++W Sbjct: 316 SCLGVTENGMAVATGSWDSFLRVW 339 Score = 53.5 bits (127), Expect = 5e-07 Identities = 37/146 (25%), Positives = 72/146 (49%), Gaps = 5/146 (3%) Frame = +1 Query: 10 RLVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGI 189 ++V+ S D + LW+ Q + + GH V + +P + S + D S KLW+ Sbjct: 156 QIVTSSGDMSCGLWDIETGLQVTSFL-GHTGDVMALSLAPQCKTFVSGACDASAKLWDIR 214 Query: 190 TGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADE---- 357 G F GH +D+ +++ + + +GS D+T +++DIRA Q+L ++ + Sbjct: 215 EGVCKQTFPGHESDINAVTFFPNGQAFATGSDDATCRLFDIRA---DQELAMYSHDNIIC 271 Query: 358 -VYAVDWSPDGEKVVSGGKDRALKLW 432 + +V +S G +++G D +W Sbjct: 272 GITSVAFSKSGRLLLAGYDDFNCNVW 297 Score = 52.0 bits (123), Expect = 1e-06 Identities = 25/73 (34%), Positives = 36/73 (49%) Frame = +1 Query: 214 RGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEK 393 RGH+A +Y + W DSR L+S S+D L VWD +P + V ++P G Sbjct: 52 RGHLAKIYAMHWGNDSRNLVSASQDGKLIVWDSHTTNKVHAIPLRSSWVMTCAYAPSGSY 111 Query: 394 VVSGGKDRALKLW 432 V GG D ++ Sbjct: 112 VACGGLDNMCSIY 124 Score = 40.8 bits (94), Expect = 0.003 Identities = 28/128 (21%), Positives = 58/128 (45%), Gaps = 4/128 (3%) Frame = +1 Query: 61 ISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQ 240 I + + + GH + +++ D + L SAS D + +W+ T V A + V Sbjct: 43 IQMRTRRTLRGHLAKIYAMHWGNDSRNLVSASQDGKLIVWDSHTTNKVHAIPLRSSWVMT 102 Query: 241 ISWSADSRLLLSGSKDSTLKVWDIRAR----KLKQDLPGHADEVYAVDWSPDGEKVVSGG 408 +++ + G D+ +++++ R ++ ++LPGH + + D + V S G Sbjct: 103 CAYAPSGSYVACGGLDNMCSIYNLKTREGNVRVSRELPGHGGYLSCCRFLDDNQIVTSSG 162 Query: 409 KDRALKLW 432 D + LW Sbjct: 163 -DMSCGLW 169 Score = 35.8 bits (81), Expect = 0.10 Identities = 26/100 (26%), Positives = 46/100 (46%), Gaps = 3/100 (3%) Frame = +1 Query: 19 SGSDDFTMFLWEPTISKQPKARMTGHQKVV---NHVYFSPDGQWLASASFDKSVKLWNGI 189 +GSDD T L++ I + M H ++ V FS G+ L + D + +W+ + Sbjct: 243 TGSDDATCRLFD--IRADQELAMYSHDNIICGITSVAFSKSGRLLLAGYDDFNCNVWDTM 300 Query: 190 TGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWD 309 + GH V + + + + +GS DS L+VW+ Sbjct: 301 KAERSGILAGHDNRVSCLGVTENGMAVATGSWDSFLRVWN 340
>GBB1_BRARE (Q6PH57) Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta| subunit 1 (Transducin beta chain 1) Length = 340 Score = 75.9 bits (185), Expect = 9e-14 Identities = 37/116 (31%), Positives = 64/116 (55%) Frame = +1 Query: 85 MTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSR 264 + GH ++ F D Q + ++S D + LW+ TG+ T F GH DV +S + D+R Sbjct: 139 LAGHTGYLSCCRFLDDNQ-IVTSSGDTTCALWDIETGQQTTTFAGHTGDVMSLSLAPDTR 197 Query: 265 LLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 L +SG+ D++ K+WD+R +Q GH ++ A+ + P+G +G D +L+ Sbjct: 198 LFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLF 253 Score = 60.8 bits (146), Expect = 3e-09 Identities = 40/141 (28%), Positives = 66/141 (46%), Gaps = 2/141 (1%) Frame = +1 Query: 16 VSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITG 195 VSG+ D + LW+ + TGH+ +N + F P+G A+ S D + +L++ Sbjct: 200 VSGACDASAKLWDVR-EGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRAD 258 Query: 196 K--FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAV 369 + V + + + +++S RLLL+G D VWD L GH + V + Sbjct: 259 QELMVYSHDNIICGITSVAFSKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDNRVSCL 318 Query: 370 DWSPDGEKVVSGGKDRALKLW 432 + DG V +G D LK+W Sbjct: 319 GVTDDGMAVATGSWDSFLKIW 339 Score = 58.2 bits (139), Expect = 2e-08 Identities = 39/146 (26%), Positives = 70/146 (47%), Gaps = 5/146 (3%) Frame = +1 Query: 10 RLVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGI 189 ++V+ S D T LW+ +Q GH V + +PD + S + D S KLW+ Sbjct: 156 QIVTSSGDTTCALWDIETGQQTTT-FAGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVR 214 Query: 190 TGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADE---- 357 G F GH +D+ I + + +GS D+T +++D+RA Q+L ++ + Sbjct: 215 EGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRA---DQELMVYSHDNIIC 271 Query: 358 -VYAVDWSPDGEKVVSGGKDRALKLW 432 + +V +S G +++G D +W Sbjct: 272 GITSVAFSKSGRLLLAGYDDFNCNVW 297 Score = 54.3 bits (129), Expect = 3e-07 Identities = 25/73 (34%), Positives = 37/73 (50%) Frame = +1 Query: 214 RGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEK 393 RGH+A +Y + W DSRLL+S S+D L +WD +P + V ++P G Sbjct: 52 RGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNY 111 Query: 394 VVSGGKDRALKLW 432 V GG D ++ Sbjct: 112 VACGGLDNICSIY 124 Score = 40.8 bits (94), Expect = 0.003 Identities = 33/169 (19%), Positives = 59/169 (34%), Gaps = 45/169 (26%) Frame = +1 Query: 61 ISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAF--------- 213 I + + + GH + +++ D + L SAS D + +W+ T V A Sbjct: 43 IQMRTRRTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMT 102 Query: 214 --------------RGHVADVYQISWS----------------------ADSRLLLSGSK 285 ++ +Y + D +++ S Sbjct: 103 CAYAPSGNYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVTSSG 162 Query: 286 DSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 D+T +WDI + GH +V ++ +PD VSG D + KLW Sbjct: 163 DTTCALWDIETGQQTTTFAGHTGDVMSLSLAPDTRLFVSGACDASAKLW 211 Score = 37.4 bits (85), Expect = 0.035 Identities = 25/100 (25%), Positives = 45/100 (45%), Gaps = 3/100 (3%) Frame = +1 Query: 19 SGSDDFTMFLWEPTISKQPKARMTGHQKVV---NHVYFSPDGQWLASASFDKSVKLWNGI 189 +GSDD T L++ + + + H ++ V FS G+ L + D + +W+ + Sbjct: 243 TGSDDATCRLFD--LRADQELMVYSHDNIICGITSVAFSKSGRLLLAGYDDFNCNVWDAL 300 Query: 190 TGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWD 309 GH V + + D + +GS DS LK+W+ Sbjct: 301 KADRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN 340
>RBBP4_BRARE (Q6P3H7) Histone-binding protein RBBP4 (Retinoblastoma-binding| protein 4) (RBBP-4) Length = 423 Score = 75.9 bits (185), Expect = 9e-14 Identities = 54/153 (35%), Positives = 80/153 (52%), Gaps = 13/153 (8%) Frame = +1 Query: 13 LVSGSDDFTMFLWE-PTISKQ-----PKARMTGHQKVVNHVYFSPDGQWL-ASASFDKSV 171 L+S SDD T+ LW+ T+ K+ K TGH VV V + + L S + D+ + Sbjct: 192 LLSASDDHTICLWDISTVPKEGKIVDAKTIFTGHTAVVEDVSWHLLHESLFGSVADDQKL 251 Query: 172 KLWN---GITGKFVTAFRGHVADVYQISWSADSRLLLS-GSKDSTLKVWDIRARKLK-QD 336 +W+ T K A H A+V +S++ S +L+ GS D T+ +WD+R KLK Sbjct: 252 MIWDTRSNNTSKPSHAVDAHTAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKLHS 311 Query: 337 LPGHADEVYAVDWSPDGEKVV-SGGKDRALKLW 432 H DE++ V WSP E ++ S G DR L +W Sbjct: 312 FESHKDEIFQVQWSPHNETILASSGTDRRLNVW 344 Score = 36.2 bits (82), Expect = 0.077 Identities = 27/82 (32%), Positives = 37/82 (45%), Gaps = 9/82 (10%) Frame = +1 Query: 214 RGHVADVYQISWSADSR-LLLSGSKDSTLKVWDI-------RARKLKQDLPGHADEVYAV 369 RGH + Y +SW+ + R LLS S D T+ +WDI + K GH V V Sbjct: 173 RGHQKEGYGLSWNPNLRSCLLSASDDHTICLWDISTVPKEGKIVDAKTIFTGHTAVVEDV 232 Query: 370 DWSPDGEKVV-SGGKDRALKLW 432 W E + S D+ L +W Sbjct: 233 SWHLLHESLFGSVADDQKLMIW 254
>GBB1_RAT (P54311) Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta| subunit 1 (Transducin beta chain 1) Length = 339 Score = 75.9 bits (185), Expect = 9e-14 Identities = 37/116 (31%), Positives = 64/116 (55%) Frame = +1 Query: 85 MTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSR 264 + GH ++ F D Q + ++S D + LW+ TG+ T F GH DV +S + D+R Sbjct: 138 LAGHTGYLSCCRFLDDNQ-IVTSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTR 196 Query: 265 LLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 L +SG+ D++ K+WD+R +Q GH ++ A+ + P+G +G D +L+ Sbjct: 197 LFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLF 252 Score = 61.6 bits (148), Expect = 2e-09 Identities = 40/141 (28%), Positives = 66/141 (46%), Gaps = 2/141 (1%) Frame = +1 Query: 16 VSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITG 195 VSG+ D + LW+ + TGH+ +N + F P+G A+ S D + +L++ Sbjct: 199 VSGACDASAKLWDVR-EGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRAD 257 Query: 196 KFVTAFRGH--VADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAV 369 + + + + + +S+S RLLL+G D VWD L GH + V + Sbjct: 258 QELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDNRVSCL 317 Query: 370 DWSPDGEKVVSGGKDRALKLW 432 + DG V +G D LK+W Sbjct: 318 GVTDDGMAVATGSWDSFLKIW 338 Score = 61.2 bits (147), Expect = 2e-09 Identities = 40/146 (27%), Positives = 71/146 (48%), Gaps = 5/146 (3%) Frame = +1 Query: 10 RLVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGI 189 ++V+ S D T LW+ +Q TGH V + +PD + S + D S KLW+ Sbjct: 155 QIVTSSGDTTCALWDIETGQQTTT-FTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVR 213 Query: 190 TGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADE---- 357 G F GH +D+ I + + +GS D+T +++D+RA Q+L ++ + Sbjct: 214 EGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRA---DQELMTYSHDNIIC 270 Query: 358 -VYAVDWSPDGEKVVSGGKDRALKLW 432 + +V +S G +++G D +W Sbjct: 271 GITSVSFSKSGRLLLAGYDDFNCNVW 296 Score = 54.3 bits (129), Expect = 3e-07 Identities = 25/73 (34%), Positives = 37/73 (50%) Frame = +1 Query: 214 RGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEK 393 RGH+A +Y + W DSRLL+S S+D L +WD +P + V ++P G Sbjct: 51 RGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNY 110 Query: 394 VVSGGKDRALKLW 432 V GG D ++ Sbjct: 111 VACGGLDNICSIY 123 Score = 40.8 bits (94), Expect = 0.003 Identities = 33/169 (19%), Positives = 59/169 (34%), Gaps = 45/169 (26%) Frame = +1 Query: 61 ISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAF--------- 213 I + + + GH + +++ D + L SAS D + +W+ T V A Sbjct: 42 IQMRTRRTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMT 101 Query: 214 --------------RGHVADVYQISWS----------------------ADSRLLLSGSK 285 ++ +Y + D +++ S Sbjct: 102 CAYAPSGNYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVTSSG 161 Query: 286 DSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 D+T +WDI + GH +V ++ +PD VSG D + KLW Sbjct: 162 DTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLW 210 Score = 36.6 bits (83), Expect = 0.059 Identities = 25/100 (25%), Positives = 44/100 (44%), Gaps = 3/100 (3%) Frame = +1 Query: 19 SGSDDFTMFLWEPTISKQPKARMTGHQKVV---NHVYFSPDGQWLASASFDKSVKLWNGI 189 +GSDD T L++ + + H ++ V FS G+ L + D + +W+ + Sbjct: 242 TGSDDATCRLFD--LRADQELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDAL 299 Query: 190 TGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWD 309 GH V + + D + +GS DS LK+W+ Sbjct: 300 KADRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN 339
>GBB1_PONPY (Q5R5W8) Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta| subunit 1 (Transducin beta chain 1) Length = 339 Score = 75.9 bits (185), Expect = 9e-14 Identities = 37/116 (31%), Positives = 64/116 (55%) Frame = +1 Query: 85 MTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSR 264 + GH ++ F D Q + ++S D + LW+ TG+ T F GH DV +S + D+R Sbjct: 138 LAGHTGYLSCCRFLDDNQ-IVTSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTR 196 Query: 265 LLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 L +SG+ D++ K+WD+R +Q GH ++ A+ + P+G +G D +L+ Sbjct: 197 LFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLF 252 Score = 63.5 bits (153), Expect = 5e-10 Identities = 41/141 (29%), Positives = 66/141 (46%), Gaps = 2/141 (1%) Frame = +1 Query: 16 VSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITG 195 VSG+ D + LW+ + TGH+ +N + F P+G A+ S D + +L++ Sbjct: 199 VSGACDASAKLWDVR-EGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRAD 257 Query: 196 KFVTAFRGH--VADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAV 369 + + + + + +S+S RLLL+G D VWD L GH D V + Sbjct: 258 QELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDDRVSCL 317 Query: 370 DWSPDGEKVVSGGKDRALKLW 432 + DG V +G D LK+W Sbjct: 318 GVTDDGMAVATGSWDSFLKIW 338 Score = 61.2 bits (147), Expect = 2e-09 Identities = 40/146 (27%), Positives = 71/146 (48%), Gaps = 5/146 (3%) Frame = +1 Query: 10 RLVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGI 189 ++V+ S D T LW+ +Q TGH V + +PD + S + D S KLW+ Sbjct: 155 QIVTSSGDTTCALWDIETGQQTTT-FTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVR 213 Query: 190 TGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADE---- 357 G F GH +D+ I + + +GS D+T +++D+RA Q+L ++ + Sbjct: 214 EGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRA---DQELMTYSHDNIIC 270 Query: 358 -VYAVDWSPDGEKVVSGGKDRALKLW 432 + +V +S G +++G D +W Sbjct: 271 GITSVSFSKSGRLLLAGYDDFNCNVW 296 Score = 54.3 bits (129), Expect = 3e-07 Identities = 25/73 (34%), Positives = 37/73 (50%) Frame = +1 Query: 214 RGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEK 393 RGH+A +Y + W DSRLL+S S+D L +WD +P + V ++P G Sbjct: 51 RGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNY 110 Query: 394 VVSGGKDRALKLW 432 V GG D ++ Sbjct: 111 VACGGLDNICSIY 123 Score = 40.8 bits (94), Expect = 0.003 Identities = 33/169 (19%), Positives = 59/169 (34%), Gaps = 45/169 (26%) Frame = +1 Query: 61 ISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAF--------- 213 I + + + GH + +++ D + L SAS D + +W+ T V A Sbjct: 42 IQMRTRRTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMT 101 Query: 214 --------------RGHVADVYQISWS----------------------ADSRLLLSGSK 285 ++ +Y + D +++ S Sbjct: 102 CAYAPSGNYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVTSSG 161 Query: 286 DSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 D+T +WDI + GH +V ++ +PD VSG D + KLW Sbjct: 162 DTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLW 210 Score = 36.6 bits (83), Expect = 0.059 Identities = 25/100 (25%), Positives = 44/100 (44%), Gaps = 3/100 (3%) Frame = +1 Query: 19 SGSDDFTMFLWEPTISKQPKARMTGHQKVV---NHVYFSPDGQWLASASFDKSVKLWNGI 189 +GSDD T L++ + + H ++ V FS G+ L + D + +W+ + Sbjct: 242 TGSDDATCRLFD--LRADQELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDAL 299 Query: 190 TGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWD 309 GH V + + D + +GS DS LK+W+ Sbjct: 300 KADRAGVLAGHDDRVSCLGVTDDGMAVATGSWDSFLKIWN 339
>GBB1_MOUSE (P62874) Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta| subunit 1 (Transducin beta chain 1) Length = 339 Score = 75.9 bits (185), Expect = 9e-14 Identities = 37/116 (31%), Positives = 64/116 (55%) Frame = +1 Query: 85 MTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSR 264 + GH ++ F D Q + ++S D + LW+ TG+ T F GH DV +S + D+R Sbjct: 138 LAGHTGYLSCCRFLDDNQ-IVTSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTR 196 Query: 265 LLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 L +SG+ D++ K+WD+R +Q GH ++ A+ + P+G +G D +L+ Sbjct: 197 LFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLF 252 Score = 61.6 bits (148), Expect = 2e-09 Identities = 40/141 (28%), Positives = 66/141 (46%), Gaps = 2/141 (1%) Frame = +1 Query: 16 VSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITG 195 VSG+ D + LW+ + TGH+ +N + F P+G A+ S D + +L++ Sbjct: 199 VSGACDASAKLWDVR-EGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRAD 257 Query: 196 KFVTAFRGH--VADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAV 369 + + + + + +S+S RLLL+G D VWD L GH + V + Sbjct: 258 QELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDNRVSCL 317 Query: 370 DWSPDGEKVVSGGKDRALKLW 432 + DG V +G D LK+W Sbjct: 318 GVTDDGMAVATGSWDSFLKIW 338 Score = 61.2 bits (147), Expect = 2e-09 Identities = 40/146 (27%), Positives = 71/146 (48%), Gaps = 5/146 (3%) Frame = +1 Query: 10 RLVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGI 189 ++V+ S D T LW+ +Q TGH V + +PD + S + D S KLW+ Sbjct: 155 QIVTSSGDTTCALWDIETGQQTTT-FTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVR 213 Query: 190 TGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADE---- 357 G F GH +D+ I + + +GS D+T +++D+RA Q+L ++ + Sbjct: 214 EGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRA---DQELMTYSHDNIIC 270 Query: 358 -VYAVDWSPDGEKVVSGGKDRALKLW 432 + +V +S G +++G D +W Sbjct: 271 GITSVSFSKSGRLLLAGYDDFNCNVW 296 Score = 54.3 bits (129), Expect = 3e-07 Identities = 25/73 (34%), Positives = 37/73 (50%) Frame = +1 Query: 214 RGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEK 393 RGH+A +Y + W DSRLL+S S+D L +WD +P + V ++P G Sbjct: 51 RGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNY 110 Query: 394 VVSGGKDRALKLW 432 V GG D ++ Sbjct: 111 VACGGLDNICSIY 123 Score = 40.8 bits (94), Expect = 0.003 Identities = 33/169 (19%), Positives = 59/169 (34%), Gaps = 45/169 (26%) Frame = +1 Query: 61 ISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAF--------- 213 I + + + GH + +++ D + L SAS D + +W+ T V A Sbjct: 42 IQMRTRRTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMT 101 Query: 214 --------------RGHVADVYQISWS----------------------ADSRLLLSGSK 285 ++ +Y + D +++ S Sbjct: 102 CAYAPSGNYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVTSSG 161 Query: 286 DSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 D+T +WDI + GH +V ++ +PD VSG D + KLW Sbjct: 162 DTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLW 210 Score = 36.6 bits (83), Expect = 0.059 Identities = 25/100 (25%), Positives = 44/100 (44%), Gaps = 3/100 (3%) Frame = +1 Query: 19 SGSDDFTMFLWEPTISKQPKARMTGHQKVV---NHVYFSPDGQWLASASFDKSVKLWNGI 189 +GSDD T L++ + + H ++ V FS G+ L + D + +W+ + Sbjct: 242 TGSDDATCRLFD--LRADQELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDAL 299 Query: 190 TGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWD 309 GH V + + D + +GS DS LK+W+ Sbjct: 300 KADRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN 339
>GBB1_HUMAN (P62873) Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta| subunit 1 (Transducin beta chain 1) Length = 339 Score = 75.9 bits (185), Expect = 9e-14 Identities = 37/116 (31%), Positives = 64/116 (55%) Frame = +1 Query: 85 MTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSR 264 + GH ++ F D Q + ++S D + LW+ TG+ T F GH DV +S + D+R Sbjct: 138 LAGHTGYLSCCRFLDDNQ-IVTSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTR 196 Query: 265 LLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 L +SG+ D++ K+WD+R +Q GH ++ A+ + P+G +G D +L+ Sbjct: 197 LFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLF 252 Score = 61.6 bits (148), Expect = 2e-09 Identities = 40/141 (28%), Positives = 66/141 (46%), Gaps = 2/141 (1%) Frame = +1 Query: 16 VSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITG 195 VSG+ D + LW+ + TGH+ +N + F P+G A+ S D + +L++ Sbjct: 199 VSGACDASAKLWDVR-EGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRAD 257 Query: 196 KFVTAFRGH--VADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAV 369 + + + + + +S+S RLLL+G D VWD L GH + V + Sbjct: 258 QELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDNRVSCL 317 Query: 370 DWSPDGEKVVSGGKDRALKLW 432 + DG V +G D LK+W Sbjct: 318 GVTDDGMAVATGSWDSFLKIW 338 Score = 61.2 bits (147), Expect = 2e-09 Identities = 40/146 (27%), Positives = 71/146 (48%), Gaps = 5/146 (3%) Frame = +1 Query: 10 RLVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGI 189 ++V+ S D T LW+ +Q TGH V + +PD + S + D S KLW+ Sbjct: 155 QIVTSSGDTTCALWDIETGQQTTT-FTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVR 213 Query: 190 TGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADE---- 357 G F GH +D+ I + + +GS D+T +++D+RA Q+L ++ + Sbjct: 214 EGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRA---DQELMTYSHDNIIC 270 Query: 358 -VYAVDWSPDGEKVVSGGKDRALKLW 432 + +V +S G +++G D +W Sbjct: 271 GITSVSFSKSGRLLLAGYDDFNCNVW 296 Score = 54.3 bits (129), Expect = 3e-07 Identities = 25/73 (34%), Positives = 37/73 (50%) Frame = +1 Query: 214 RGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEK 393 RGH+A +Y + W DSRLL+S S+D L +WD +P + V ++P G Sbjct: 51 RGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNY 110 Query: 394 VVSGGKDRALKLW 432 V GG D ++ Sbjct: 111 VACGGLDNICSIY 123 Score = 40.8 bits (94), Expect = 0.003 Identities = 33/169 (19%), Positives = 59/169 (34%), Gaps = 45/169 (26%) Frame = +1 Query: 61 ISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAF--------- 213 I + + + GH + +++ D + L SAS D + +W+ T V A Sbjct: 42 IQMRTRRTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMT 101 Query: 214 --------------RGHVADVYQISWS----------------------ADSRLLLSGSK 285 ++ +Y + D +++ S Sbjct: 102 CAYAPSGNYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVTSSG 161 Query: 286 DSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 D+T +WDI + GH +V ++ +PD VSG D + KLW Sbjct: 162 DTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLW 210 Score = 36.6 bits (83), Expect = 0.059 Identities = 25/100 (25%), Positives = 44/100 (44%), Gaps = 3/100 (3%) Frame = +1 Query: 19 SGSDDFTMFLWEPTISKQPKARMTGHQKVV---NHVYFSPDGQWLASASFDKSVKLWNGI 189 +GSDD T L++ + + H ++ V FS G+ L + D + +W+ + Sbjct: 242 TGSDDATCRLFD--LRADQELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDAL 299 Query: 190 TGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWD 309 GH V + + D + +GS DS LK+W+ Sbjct: 300 KADRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN 339
>GBB1_CANFA (P62872) Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta| subunit 1 (Transducin beta chain 1) Length = 339 Score = 75.9 bits (185), Expect = 9e-14 Identities = 37/116 (31%), Positives = 64/116 (55%) Frame = +1 Query: 85 MTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSR 264 + GH ++ F D Q + ++S D + LW+ TG+ T F GH DV +S + D+R Sbjct: 138 LAGHTGYLSCCRFLDDNQ-IVTSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTR 196 Query: 265 LLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 L +SG+ D++ K+WD+R +Q GH ++ A+ + P+G +G D +L+ Sbjct: 197 LFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLF 252 Score = 61.6 bits (148), Expect = 2e-09 Identities = 40/141 (28%), Positives = 66/141 (46%), Gaps = 2/141 (1%) Frame = +1 Query: 16 VSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITG 195 VSG+ D + LW+ + TGH+ +N + F P+G A+ S D + +L++ Sbjct: 199 VSGACDASAKLWDVR-EGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRAD 257 Query: 196 KFVTAFRGH--VADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAV 369 + + + + + +S+S RLLL+G D VWD L GH + V + Sbjct: 258 QELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDNRVSCL 317 Query: 370 DWSPDGEKVVSGGKDRALKLW 432 + DG V +G D LK+W Sbjct: 318 GVTDDGMAVATGSWDSFLKIW 338 Score = 61.2 bits (147), Expect = 2e-09 Identities = 40/146 (27%), Positives = 71/146 (48%), Gaps = 5/146 (3%) Frame = +1 Query: 10 RLVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGI 189 ++V+ S D T LW+ +Q TGH V + +PD + S + D S KLW+ Sbjct: 155 QIVTSSGDTTCALWDIETGQQTTT-FTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVR 213 Query: 190 TGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADE---- 357 G F GH +D+ I + + +GS D+T +++D+RA Q+L ++ + Sbjct: 214 EGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRA---DQELMTYSHDNIIC 270 Query: 358 -VYAVDWSPDGEKVVSGGKDRALKLW 432 + +V +S G +++G D +W Sbjct: 271 GITSVSFSKSGRLLLAGYDDFNCNVW 296 Score = 54.3 bits (129), Expect = 3e-07 Identities = 25/73 (34%), Positives = 37/73 (50%) Frame = +1 Query: 214 RGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEK 393 RGH+A +Y + W DSRLL+S S+D L +WD +P + V ++P G Sbjct: 51 RGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNY 110 Query: 394 VVSGGKDRALKLW 432 V GG D ++ Sbjct: 111 VACGGLDNICSIY 123 Score = 40.8 bits (94), Expect = 0.003 Identities = 33/169 (19%), Positives = 59/169 (34%), Gaps = 45/169 (26%) Frame = +1 Query: 61 ISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAF--------- 213 I + + + GH + +++ D + L SAS D + +W+ T V A Sbjct: 42 IQMRTRRTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMT 101 Query: 214 --------------RGHVADVYQISWS----------------------ADSRLLLSGSK 285 ++ +Y + D +++ S Sbjct: 102 CAYAPSGNYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVTSSG 161 Query: 286 DSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 D+T +WDI + GH +V ++ +PD VSG D + KLW Sbjct: 162 DTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLW 210 Score = 36.6 bits (83), Expect = 0.059 Identities = 25/100 (25%), Positives = 44/100 (44%), Gaps = 3/100 (3%) Frame = +1 Query: 19 SGSDDFTMFLWEPTISKQPKARMTGHQKVV---NHVYFSPDGQWLASASFDKSVKLWNGI 189 +GSDD T L++ + + H ++ V FS G+ L + D + +W+ + Sbjct: 242 TGSDDATCRLFD--LRADQELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDAL 299 Query: 190 TGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWD 309 GH V + + D + +GS DS LK+W+ Sbjct: 300 KADRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN 339
>GBB1_BOVIN (P62871) Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta| subunit 1 (Transducin beta chain 1) Length = 339 Score = 75.9 bits (185), Expect = 9e-14 Identities = 37/116 (31%), Positives = 64/116 (55%) Frame = +1 Query: 85 MTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSR 264 + GH ++ F D Q + ++S D + LW+ TG+ T F GH DV +S + D+R Sbjct: 138 LAGHTGYLSCCRFLDDNQ-IVTSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTR 196 Query: 265 LLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 L +SG+ D++ K+WD+R +Q GH ++ A+ + P+G +G D +L+ Sbjct: 197 LFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLF 252 Score = 61.6 bits (148), Expect = 2e-09 Identities = 40/141 (28%), Positives = 66/141 (46%), Gaps = 2/141 (1%) Frame = +1 Query: 16 VSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITG 195 VSG+ D + LW+ + TGH+ +N + F P+G A+ S D + +L++ Sbjct: 199 VSGACDASAKLWDVR-EGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRAD 257 Query: 196 KFVTAFRGH--VADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAV 369 + + + + + +S+S RLLL+G D VWD L GH + V + Sbjct: 258 QELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDNRVSCL 317 Query: 370 DWSPDGEKVVSGGKDRALKLW 432 + DG V +G D LK+W Sbjct: 318 GVTDDGMAVATGSWDSFLKIW 338 Score = 61.2 bits (147), Expect = 2e-09 Identities = 40/146 (27%), Positives = 71/146 (48%), Gaps = 5/146 (3%) Frame = +1 Query: 10 RLVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGI 189 ++V+ S D T LW+ +Q TGH V + +PD + S + D S KLW+ Sbjct: 155 QIVTSSGDTTCALWDIETGQQTTT-FTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVR 213 Query: 190 TGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADE---- 357 G F GH +D+ I + + +GS D+T +++D+RA Q+L ++ + Sbjct: 214 EGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRA---DQELMTYSHDNIIC 270 Query: 358 -VYAVDWSPDGEKVVSGGKDRALKLW 432 + +V +S G +++G D +W Sbjct: 271 GITSVSFSKSGRLLLAGYDDFNCNVW 296 Score = 54.3 bits (129), Expect = 3e-07 Identities = 25/73 (34%), Positives = 37/73 (50%) Frame = +1 Query: 214 RGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEK 393 RGH+A +Y + W DSRLL+S S+D L +WD +P + V ++P G Sbjct: 51 RGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNY 110 Query: 394 VVSGGKDRALKLW 432 V GG D ++ Sbjct: 111 VACGGLDNICSIY 123 Score = 40.8 bits (94), Expect = 0.003 Identities = 33/169 (19%), Positives = 59/169 (34%), Gaps = 45/169 (26%) Frame = +1 Query: 61 ISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAF--------- 213 I + + + GH + +++ D + L SAS D + +W+ T V A Sbjct: 42 IQMRTRRTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMT 101 Query: 214 --------------RGHVADVYQISWS----------------------ADSRLLLSGSK 285 ++ +Y + D +++ S Sbjct: 102 CAYAPSGNYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVTSSG 161 Query: 286 DSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 D+T +WDI + GH +V ++ +PD VSG D + KLW Sbjct: 162 DTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLW 210 Score = 36.6 bits (83), Expect = 0.059 Identities = 25/100 (25%), Positives = 44/100 (44%), Gaps = 3/100 (3%) Frame = +1 Query: 19 SGSDDFTMFLWEPTISKQPKARMTGHQKVV---NHVYFSPDGQWLASASFDKSVKLWNGI 189 +GSDD T L++ + + H ++ V FS G+ L + D + +W+ + Sbjct: 242 TGSDDATCRLFD--LRADQELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDAL 299 Query: 190 TGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWD 309 GH V + + D + +GS DS LK+W+ Sbjct: 300 KADRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN 339
>APAF_RAT (Q9EPV5) Apoptotic protease-activating factor 1 (Apaf-1)| Length = 1249 Score = 75.9 bits (185), Expect = 9e-14 Identities = 42/115 (36%), Positives = 61/115 (53%), Gaps = 2/115 (1%) Frame = +1 Query: 94 HQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSR--L 267 H+ V FS D ++A+ S DK VK+W+ TGK V + H V ++ S L Sbjct: 656 HEDEVLCCAFSSDDSYIATCSVDKKVKIWDSGTGKLVHTYEEHSEQVNCCHFTNKSNHLL 715 Query: 268 LLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 L +GS DS LK+WD+ ++ + + GH + V +SPD E + S D LKLW Sbjct: 716 LATGSNDSFLKLWDLNQKECRNTMFGHTNSVTHCRFSPDDELLASCSADGTLKLW 770 Score = 70.5 bits (171), Expect = 4e-12 Identities = 40/114 (35%), Positives = 61/114 (53%) Frame = +1 Query: 91 GHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLL 270 GH+K V H+ F+ DG+ L S+S D +++WN T ++V + H V DSR L Sbjct: 1001 GHKKAVRHIQFTADGKTLISSSEDSVIQVWNWQTEEYV-FLQAHQETVKDFRLLRDSR-L 1058 Query: 271 LSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 LS S D T+KVW++ ++++D H V + S D K S D+ K+W Sbjct: 1059 LSWSFDGTVKVWNVITGRIERDFTCHQGTVLSCAISSDATKFSSTSADKTAKIW 1112 Score = 63.2 bits (152), Expect = 6e-10 Identities = 41/140 (29%), Positives = 64/140 (45%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 L+S S+D + +W + + HQ+ V D + L S SFD +VK+WN IT Sbjct: 1018 LISSSEDSVIQVWN--WQTEEYVFLQAHQETVKDFRLLRDSR-LLSWSFDGTVKVWNVIT 1074 Query: 193 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVD 372 G+ F H V + S+D+ S S D T K+W +L GH V Sbjct: 1075 GRIERDFTCHQGTVLSCAISSDATKFSSTSADKTAKIWSFELPSPLHELKGHNSCVRCSA 1134 Query: 373 WSPDGEKVVSGGKDRALKLW 432 +S DG + +G + +++W Sbjct: 1135 FSLDGILLATGDDNGEIRIW 1154 Score = 60.1 bits (144), Expect = 5e-09 Identities = 49/195 (25%), Positives = 78/195 (40%), Gaps = 55/195 (28%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 L +GS+D + LW+ K+ + M GH V H FSPD + LAS S D ++KLW+ + Sbjct: 716 LATGSNDSFLKLWDLN-QKECRNTMFGHTNSVTHCRFSPDDELLASCSADGTLKLWDVRS 774 Query: 193 G---------KFVTAFRGHVADVYQI----SWSADSRLLLSGSKDSTL------------ 297 +F + DV I SWSAD ++ +K+ L Sbjct: 775 ANEKKSINVKRFFLSSEDPPEDVEVIVKCCSWSADGDRIIVAAKNKVLLLDIHTSGLLTE 834 Query: 298 ------------------------------KVWDIRARKLKQDLPGHADEVYAVDWSPDG 387 ++W+I +R D GH V+ V +SPDG Sbjct: 835 IHTGHHSTIQYCDFSPYDHLAVIALSQYCVELWNIDSRVKVADCRGHLSWVHGVMFSPDG 894 Query: 388 EKVVSGGKDRALKLW 432 ++ D+ +++W Sbjct: 895 SSFLTASDDQTIRVW 909 Score = 51.6 bits (122), Expect = 2e-06 Identities = 42/150 (28%), Positives = 70/150 (46%), Gaps = 9/150 (6%) Frame = +1 Query: 10 RLVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGI 189 RL+S S D T+ +W I+ + + T HQ V S D +S S DK+ K+W+ Sbjct: 1057 RLLSWSFDGTVKVWN-VITGRIERDFTCHQGTVLSCAISSDATKFSSTSADKTAKIWSFE 1115 Query: 190 TGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKL---------KQDLP 342 + +GH + V ++S D LL +G + +++W++ +L ++ Sbjct: 1116 LPSPLHELKGHNSCVRCSAFSLDGILLATGDDNGEIRIWNVSDGQLLHLCAPISIEEGTA 1175 Query: 343 GHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 H V V +SPD + +VS G LK W Sbjct: 1176 THGGWVTDVCFSPDRKMLVSAG--GYLKWW 1203 Score = 47.8 bits (112), Expect = 3e-05 Identities = 25/76 (32%), Positives = 38/76 (50%) Frame = +1 Query: 88 TGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRL 267 TGH + + FSP A V+LWN + V RGH++ V+ + +S D Sbjct: 837 TGHHSTIQYCDFSPYDHLAVIALSQYCVELWNIDSRVKVADCRGHLSWVHGVMFSPDGSS 896 Query: 268 LLSGSKDSTLKVWDIR 315 L+ S D T++VW+ R Sbjct: 897 FLTASDDQTIRVWETR 912 Score = 35.8 bits (81), Expect = 0.10 Identities = 25/103 (24%), Positives = 51/103 (49%) Frame = +1 Query: 124 SPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKV 303 SP +++A + ++K+ + ++ GH V I ++AD + L+S S+DS ++V Sbjct: 970 SPHLEYVAFGDEEGAIKIIELPNNRVFSSGIGHKKAVRHIQFTADGKTLISSSEDSVIQV 1029 Query: 304 WDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 W+ + + L H + V D +++S D +K+W Sbjct: 1030 WNWQTEEY-VFLQAHQETVKDFRLLRD-SRLLSWSFDGTVKVW 1070
>WSB2_MOUSE (O54929) WD repeat and SOCS box-containing protein 2 (WSB-2) (SOCS| box-containing WD protein SWiP-2) Length = 404 Score = 75.5 bits (184), Expect = 1e-13 Identities = 45/142 (31%), Positives = 76/142 (53%), Gaps = 2/142 (1%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQW-LASASFDKSVKLWN-G 186 L +G +D + +WE ++GHQ VV + F+P G L SAS DK++++W+ Sbjct: 126 LATGLNDGQIKIWEVQTGLL-LLNLSGHQDVVRDLSFTPSGSLILVSASRDKTLRIWDLN 184 Query: 187 ITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYA 366 GK + GH+ VY S S D +L S + + ++ +W +R+ L + L GH V + Sbjct: 185 KHGKQIQVLSGHLQWVYCCSISPDCSMLCSAAGEKSVFLWSMRSYTLIRKLEGHQSSVVS 244 Query: 367 VDWSPDGEKVVSGGKDRALKLW 432 D+SPD +V+ D ++ +W Sbjct: 245 CDFSPDSALLVTASYDTSVIMW 266 Score = 67.4 bits (163), Expect = 3e-11 Identities = 46/152 (30%), Positives = 74/152 (48%), Gaps = 12/152 (7%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 LVS S D T+ +W+ + ++GH + V SPD L SA+ +KSV LW+ + Sbjct: 169 LVSASRDKTLRIWDLNKHGKQIQVLSGHLQWVYCCSISPDCSMLCSAAGEKSVFLWSMRS 228 Query: 193 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWD----IRARKL--------KQD 336 + GH + V +S DS LL++ S D+++ +WD R R L D Sbjct: 229 YTLIRKLEGHQSSVVSCDFSPDSALLVTASYDTSVIMWDPYTGARLRSLHHTQLEPTMDD 288 Query: 337 LPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 H + +V +SP+G + + DR L++W Sbjct: 289 SDVHMSSLRSVCFSPEGLYLATVADDRLLRIW 320 Score = 43.5 bits (101), Expect = 5e-04 Identities = 18/57 (31%), Positives = 34/57 (59%), Gaps = 1/57 (1%) Frame = +1 Query: 265 LLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKV-VSGGKDRALKLW 432 +L +G D +K+W+++ L +L GH D V + ++P G + VS +D+ L++W Sbjct: 125 ILATGLNDGQIKIWEVQTGLLLLNLSGHQDVVRDLSFTPSGSLILVSASRDKTLRIW 181
>RBBP7_XENTR (Q6P315) Histone-binding protein RBBP7 (Retinoblastoma-binding| protein 7) (RBBP-7) Length = 425 Score = 75.5 bits (184), Expect = 1e-13 Identities = 55/155 (35%), Positives = 80/155 (51%), Gaps = 15/155 (9%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPK--------ARMTGHQKVVNHVYFSPDGQWL-ASASFDK 165 L+S SDD T+ LW+ IS PK A TGH VV V + + L S + D+ Sbjct: 192 LLSASDDHTVCLWD--ISAGPKEGKVVDAKAIFTGHSAVVEDVAWHLLHESLFGSVADDQ 249 Query: 166 SVKLWN---GITGKFVTAFRGHVADVYQISWSADSRLLLS-GSKDSTLKVWDIRARKLK- 330 + +W+ T K + H A+V +S++ S +L+ GS D T+ +WD+R KLK Sbjct: 250 KLMIWDTRSNTTSKPSHSVDAHTAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKL 309 Query: 331 QDLPGHADEVYAVDWSPDGEKVV-SGGKDRALKLW 432 H DE++ V WSP E ++ S G DR L +W Sbjct: 310 HSFESHKDEIFQVHWSPHNETILASSGTDRRLNVW 344
>RBBP7_XENLA (Q8AVH1) Histone-binding protein RBBP7 (Retinoblastoma-binding| protein 7) (RBBP-7) Length = 425 Score = 75.5 bits (184), Expect = 1e-13 Identities = 55/155 (35%), Positives = 80/155 (51%), Gaps = 15/155 (9%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPK--------ARMTGHQKVVNHVYFSPDGQWL-ASASFDK 165 L+S SDD T+ LW+ IS PK A TGH VV V + + L S + D+ Sbjct: 192 LLSASDDHTVCLWD--ISAGPKEGKVVDAKAVFTGHSAVVEDVAWHLLHESLFGSVADDQ 249 Query: 166 SVKLWN---GITGKFVTAFRGHVADVYQISWSADSRLLLS-GSKDSTLKVWDIRARKLK- 330 + +W+ T K + H A+V +S++ S +L+ GS D T+ +WD+R KLK Sbjct: 250 KLMIWDTRSNTTSKPSHSVDAHTAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKL 309 Query: 331 QDLPGHADEVYAVDWSPDGEKVV-SGGKDRALKLW 432 H DE++ V WSP E ++ S G DR L +W Sbjct: 310 HSFESHKDEIFQVHWSPHNETILASSGTDRRLNVW 344
>PRP46_ASHGO (Q75BY3) Pre-mRNA-splicing factor PRP46 (Pre-mRNA-processing| protein 46) Length = 425 Score = 75.5 bits (184), Expect = 1e-13 Identities = 44/138 (31%), Positives = 68/138 (49%) Frame = +1 Query: 19 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 198 +GS+D T+ +W+ K K + GH V + S ++ SAS DK VK W+ Sbjct: 131 TGSNDSTIRVWDLATGKL-KVTLQGHIMTVRDICISARHPYMFSASQDKLVKCWDLERNT 189 Query: 199 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWS 378 V F G ++ V+ + L++S +DS ++VWDIR+R L GH + V Sbjct: 190 VVRDFHGTLSGVHSVDLHPSLDLIVSAGRDSVVRVWDIRSRSCVLTLAGHRGPINKVRCL 249 Query: 379 PDGEKVVSGGKDRALKLW 432 P ++VS D +KLW Sbjct: 250 PVDPQIVSCSTDATVKLW 267 Score = 75.5 bits (184), Expect = 1e-13 Identities = 41/145 (28%), Positives = 71/145 (48%), Gaps = 9/145 (6%) Frame = +1 Query: 25 SDDFTMFLWEPTISKQPKAR--------MTGHQKVVNHVYFSP-DGQWLASASFDKSVKL 177 +D + +E +S++P+ + GH V V P D W A+ S D ++++ Sbjct: 81 ADTSALARYEEVVSQKPQWHAPWKLTRVINGHTGWVRCVCVDPVDNAWFATGSNDSTIRV 140 Query: 178 WNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADE 357 W+ TGK +GH+ V I SA + S S+D +K WD+ + +D G Sbjct: 141 WDLATGKLKVTLQGHIMTVRDICISARHPYMFSASQDKLVKCWDLERNTVVRDFHGTLSG 200 Query: 358 VYAVDWSPDGEKVVSGGKDRALKLW 432 V++VD P + +VS G+D +++W Sbjct: 201 VHSVDLHPSLDLIVSAGRDSVVRVW 225 Score = 46.6 bits (109), Expect = 6e-05 Identities = 35/149 (23%), Positives = 71/149 (47%), Gaps = 8/149 (5%) Frame = +1 Query: 10 RLVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGI 189 ++VS S D T+ LW+ ++ +P +T H++ V + F+P ASA D ++ W + Sbjct: 254 QIVSCSTDATVKLWD-LVAGKPMKTLTHHKRNVRDLAFNPTEFSFASACTD-DIRSWKLV 311 Query: 190 TGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRA----RKLKQD-LPGHAD 354 G+ +T F + +L +G L +D + +KL+ +PG + Sbjct: 312 DGQLLTNFNSEALGIVNTLACNQDGVLFAGGDTGELSFFDYKTGHKFQKLETTAMPGSLE 371 Query: 355 E---VYAVDWSPDGEKVVSGGKDRALKLW 432 V A + G ++++ +D+++K+W Sbjct: 372 SEKGVLASTFDRTGLRLLTCERDKSIKIW 400
>PRP46_SCHPO (O13615) Pre-mRNA-splicing factor prp46 (Pre-mRNA-processing| protein 5) (Complexed with cdc5 protein 1) Length = 473 Score = 75.5 bits (184), Expect = 1e-13 Identities = 42/138 (30%), Positives = 70/138 (50%) Frame = +1 Query: 19 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 198 +G+ D T+ +W+ S K +TGH V + SP +L S DK VK W+ T K Sbjct: 180 TGAGDRTIKIWD-LASGVLKLTLTGHIATVRGLAVSPRHPYLFSCGEDKMVKCWDLETNK 238 Query: 199 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWS 378 + + GH++ VY + +L++ +D+ +VWD+R R+ L GH V ++ Sbjct: 239 VIRHYHGHLSGVYALKLHPTLDVLVTAGRDAVARVWDMRTRQNVHVLSGHKSTVASLAVQ 298 Query: 379 PDGEKVVSGGKDRALKLW 432 +VV+G D ++LW Sbjct: 299 EFDPQVVTGSMDSTIRLW 316 Score = 68.9 bits (167), Expect = 1e-11 Identities = 33/116 (28%), Positives = 58/116 (50%) Frame = +1 Query: 85 MTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSR 264 ++GH V V P QW + + D+++K+W+ +G GH+A V ++ S Sbjct: 159 ISGHLGWVRCVDVEPGNQWFCTGAGDRTIKIWDLASGVLKLTLTGHIATVRGLAVSPRHP 218 Query: 265 LLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 L S +D +K WD+ K+ + GH VYA+ P + +V+ G+D ++W Sbjct: 219 YLFSCGEDKMVKCWDLETNKVIRHYHGHLSGVYALKLHPTLDVLVTAGRDAVARVW 274 Score = 58.5 bits (140), Expect = 1e-08 Identities = 42/149 (28%), Positives = 78/149 (52%), Gaps = 8/149 (5%) Frame = +1 Query: 10 RLVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGI 189 ++V+GS D T+ LW+ K +T H+K V + PD AS S D ++K W Sbjct: 303 QVVTGSMDSTIRLWDLAAGKT-LTTLTHHKKTVRALSLHPDEFTFASGSSD-NIKHWKFP 360 Query: 190 TGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDL-----PGHAD 354 G F+ F GH A V +S ++D+ ++ SG+ + ++ WD ++ Q+L PG D Sbjct: 361 EGAFMGNFEGHNAIVNTLSINSDN-VMFSGADNGSMCFWDWKSGHKYQELQSVVQPGSLD 419 Query: 355 E---VYAVDWSPDGEKVVSGGKDRALKLW 432 ++A + G ++++ D+++K++ Sbjct: 420 SEAGIFASSFDKTGLRLITCEADKSVKIY 448
>TBL1R_MOUSE (Q8BHJ5) F-box-like/WD-repeat protein TBL1XR1 (Transducin beta-like| 1X-related protein 1) (Nuclear receptor corepressor/HDAC3 complex subunit TBLR1) (TBL1-related protein 1) Length = 514 Score = 75.5 bits (184), Expect = 1e-13 Identities = 41/130 (31%), Positives = 64/130 (49%), Gaps = 9/130 (6%) Frame = +1 Query: 70 QPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISW 249 +P GH VN + + P G LAS S D ++K+W+ V + H ++Y I W Sbjct: 340 RPIKTFQGHTNEVNAIKWDPTGNLLASCSDDMTLKIWSMKQDNCVHDLQAHNKEIYTIKW 399 Query: 250 SAD---------SRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVS 402 S + +L S S DST+++WD+ L H + VY+V +SPDG + S Sbjct: 400 SPTGPGTNNPNANLMLASASFDSTVRLWDVDRGICIHTLTKHQEPVYSVAFSPDGRYLAS 459 Query: 403 GGKDRALKLW 432 G D+ + +W Sbjct: 460 GSFDKCVHIW 469 Score = 66.6 bits (161), Expect = 5e-11 Identities = 45/145 (31%), Positives = 67/145 (46%), Gaps = 11/145 (7%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKA--RMTGHQKVVNHVYFSPDGQ---------WLASASF 159 L S SDD T+ +W KQ + H K + + +SP G LASASF Sbjct: 364 LASCSDDMTLKIWS---MKQDNCVHDLQAHNKEIYTIKWSPTGPGTNNPNANLMLASASF 420 Query: 160 DKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDL 339 D +V+LW+ G + H VY +++S D R L SGS D + +W+ + L Sbjct: 421 DSTVRLWDVDRGICIHTLTKHQEPVYSVAFSPDGRYLASGSFDKCVHIWNTQTGALVHSY 480 Query: 340 PGHADEVYAVDWSPDGEKVVSGGKD 414 G ++ V W+ G+KV + D Sbjct: 481 RG-TGGIFEVCWNAAGDKVGASASD 504 Score = 65.9 bits (159), Expect = 9e-11 Identities = 38/101 (37%), Positives = 58/101 (57%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 L S S D T+ LW+ +T HQ+ V V FSPDG++LAS SFDK V +WN T Sbjct: 415 LASASFDSTVRLWDVDRGICIHT-LTKHQEPVYSVAFSPDGRYLASGSFDKCVHIWNTQT 473 Query: 193 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIR 315 G V ++RG ++++ W+A + + + D ++ V D+R Sbjct: 474 GALVHSYRG-TGGIFEVCWNAAGDKVGASASDGSVCVLDLR 513 Score = 60.5 bits (145), Expect = 4e-09 Identities = 39/149 (26%), Positives = 62/149 (41%), Gaps = 9/149 (6%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 ++S D T +W+ + K + H V + + + AS S D + + Sbjct: 281 ILSAGVDKTTIIWDAHTG-EAKQQFPFHSAPALDVDWQSNNTF-ASCSTDMCIHVCKLGQ 338 Query: 193 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVD 372 + + F+GH +V I W LL S S D TLK+W ++ DL H E+Y + Sbjct: 339 DRPIKTFQGHTNEVNAIKWDPTGNLLASCSDDMTLKIWSMKQDNCVHDLQAHNKEIYTIK 398 Query: 373 WSPDGE---------KVVSGGKDRALKLW 432 WSP G + S D ++LW Sbjct: 399 WSPTGPGTNNPNANLMLASASFDSTVRLW 427 Score = 57.4 bits (137), Expect = 3e-08 Identities = 36/140 (25%), Positives = 63/140 (45%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 L +GS D +W T + + H+ + + ++ G ++ SA DK+ +W+ T Sbjct: 240 LATGSYDGFARIW--TKDGNLASTLGQHKGPIFALKWNKKGNFILSAGVDKTTIIWDAHT 297 Query: 193 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVD 372 G+ F H A + W +++ S S D + V + + + GH +EV A+ Sbjct: 298 GEAKQQFPFHSAPALDVDWQSNN-TFASCSTDMCIHVCKLGQDRPIKTFQGHTNEVNAIK 356 Query: 373 WSPDGEKVVSGGKDRALKLW 432 W P G + S D LK+W Sbjct: 357 WDPTGNLLASCSDDMTLKIW 376 Score = 52.4 bits (124), Expect = 1e-06 Identities = 32/130 (24%), Positives = 57/130 (43%), Gaps = 14/130 (10%) Frame = +1 Query: 85 MTGHQKVVNHVYFSPDGQWLASASFDKSVKLW----NGITGKFVTAFRGHV--------- 225 + GH+ V ++P LAS S D + ++W N +G R + Sbjct: 165 LRGHESEVFICAWNPVSDLLASGSGDSTARIWNLSENSTSGPTQLVLRHCIREGGQDVPS 224 Query: 226 -ADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVS 402 DV + W+++ LL +GS D ++W + L L H ++A+ W+ G ++S Sbjct: 225 NKDVTSLDWNSEGTLLATGSYDGFARIW-TKDGNLASTLGQHKGPIFALKWNKKGNFILS 283 Query: 403 GGKDRALKLW 432 G D+ +W Sbjct: 284 AGVDKTTIIW 293
>TBL1R_HUMAN (Q9BZK7) F-box-like/WD-repeat protein TBL1XR1 (Transducin beta-like| 1X-related protein 1) (Nuclear receptor corepressor/HDAC3 complex subunit TBLR1) (TBL1-related protein 1) Length = 514 Score = 75.5 bits (184), Expect = 1e-13 Identities = 41/130 (31%), Positives = 64/130 (49%), Gaps = 9/130 (6%) Frame = +1 Query: 70 QPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISW 249 +P GH VN + + P G LAS S D ++K+W+ V + H ++Y I W Sbjct: 340 RPIKTFQGHTNEVNAIKWDPTGNLLASCSDDMTLKIWSMKQDNCVHDLQAHNKEIYTIKW 399 Query: 250 SAD---------SRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVS 402 S + +L S S DST+++WD+ L H + VY+V +SPDG + S Sbjct: 400 SPTGPGTNNPNANLMLASASFDSTVRLWDVDRGICIHTLTKHQEPVYSVAFSPDGRYLAS 459 Query: 403 GGKDRALKLW 432 G D+ + +W Sbjct: 460 GSFDKCVHIW 469 Score = 66.6 bits (161), Expect = 5e-11 Identities = 45/145 (31%), Positives = 67/145 (46%), Gaps = 11/145 (7%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKA--RMTGHQKVVNHVYFSPDGQ---------WLASASF 159 L S SDD T+ +W KQ + H K + + +SP G LASASF Sbjct: 364 LASCSDDMTLKIWS---MKQDNCVHDLQAHNKEIYTIKWSPTGPGTNNPNANLMLASASF 420 Query: 160 DKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDL 339 D +V+LW+ G + H VY +++S D R L SGS D + +W+ + L Sbjct: 421 DSTVRLWDVDRGICIHTLTKHQEPVYSVAFSPDGRYLASGSFDKCVHIWNTQTGALVHSY 480 Query: 340 PGHADEVYAVDWSPDGEKVVSGGKD 414 G ++ V W+ G+KV + D Sbjct: 481 RG-TGGIFEVCWNAAGDKVGASASD 504 Score = 65.9 bits (159), Expect = 9e-11 Identities = 38/101 (37%), Positives = 58/101 (57%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 L S S D T+ LW+ +T HQ+ V V FSPDG++LAS SFDK V +WN T Sbjct: 415 LASASFDSTVRLWDVDRGICIHT-LTKHQEPVYSVAFSPDGRYLASGSFDKCVHIWNTQT 473 Query: 193 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIR 315 G V ++RG ++++ W+A + + + D ++ V D+R Sbjct: 474 GALVHSYRG-TGGIFEVCWNAAGDKVGASASDGSVCVLDLR 513 Score = 60.5 bits (145), Expect = 4e-09 Identities = 39/149 (26%), Positives = 62/149 (41%), Gaps = 9/149 (6%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 ++S D T +W+ + K + H V + + + AS S D + + Sbjct: 281 ILSAGVDKTTIIWDAHTG-EAKQQFPFHSAPALDVDWQSNNTF-ASCSTDMCIHVCKLGQ 338 Query: 193 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVD 372 + + F+GH +V I W LL S S D TLK+W ++ DL H E+Y + Sbjct: 339 DRPIKTFQGHTNEVNAIKWDPTGNLLASCSDDMTLKIWSMKQDNCVHDLQAHNKEIYTIK 398 Query: 373 WSPDGE---------KVVSGGKDRALKLW 432 WSP G + S D ++LW Sbjct: 399 WSPTGPGTNNPNANLMLASASFDSTVRLW 427 Score = 57.4 bits (137), Expect = 3e-08 Identities = 36/140 (25%), Positives = 63/140 (45%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 L +GS D +W T + + H+ + + ++ G ++ SA DK+ +W+ T Sbjct: 240 LATGSYDGFARIW--TKDGNLASTLGQHKGPIFALKWNKKGNFILSAGVDKTTIIWDAHT 297 Query: 193 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVD 372 G+ F H A + W +++ S S D + V + + + GH +EV A+ Sbjct: 298 GEAKQQFPFHSAPALDVDWQSNN-TFASCSTDMCIHVCKLGQDRPIKTFQGHTNEVNAIK 356 Query: 373 WSPDGEKVVSGGKDRALKLW 432 W P G + S D LK+W Sbjct: 357 WDPTGNLLASCSDDMTLKIW 376 Score = 52.8 bits (125), Expect = 8e-07 Identities = 32/130 (24%), Positives = 57/130 (43%), Gaps = 14/130 (10%) Frame = +1 Query: 85 MTGHQKVVNHVYFSPDGQWLASASFDKSVKLW----NGITGKFVTAFRGHV--------- 225 + GH+ V ++P LAS S D + ++W N +G R + Sbjct: 165 LRGHESEVFICAWNPVSDLLASGSGDSTARIWNLSENSTSGSTQLVLRHCIREGGQDVPS 224 Query: 226 -ADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVS 402 DV + W+++ LL +GS D ++W + L L H ++A+ W+ G ++S Sbjct: 225 NKDVTSLDWNSEGTLLATGSYDGFARIW-TKDGNLASTLGQHKGPIFALKWNKKGNFILS 283 Query: 403 GGKDRALKLW 432 G D+ +W Sbjct: 284 AGVDKTTIIW 293
>RBBP7_CHICK (Q9I8G9) Histone-binding protein RBBP7 (Retinoblastoma-binding| protein 7) (RBBP-7) (Retinoblastoma-binding protein p46) Length = 424 Score = 75.5 bits (184), Expect = 1e-13 Identities = 55/155 (35%), Positives = 80/155 (51%), Gaps = 15/155 (9%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPK--------ARMTGHQKVVNHVYFSPDGQWL-ASASFDK 165 L+S SDD T+ LW+ IS PK A TGH VV V + + L S + D+ Sbjct: 191 LLSASDDHTVCLWD--ISAGPKEGKIVDAKAIFTGHSAVVEDVAWHLLHESLFGSVADDQ 248 Query: 166 SVKLWN---GITGKFVTAFRGHVADVYQISWSADSRLLLS-GSKDSTLKVWDIRARKLK- 330 + +W+ T K + H A+V +S++ S +L+ GS D T+ +WD+R KLK Sbjct: 249 KLMIWDTRSNTTSKPSHSVDAHTAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKL 308 Query: 331 QDLPGHADEVYAVDWSPDGEKVV-SGGKDRALKLW 432 H DE++ V WSP E ++ S G DR L +W Sbjct: 309 HSFESHKDEIFQVHWSPHNETILASSGTDRRLNVW 343 Score = 35.4 bits (80), Expect = 0.13 Identities = 27/82 (32%), Positives = 39/82 (47%), Gaps = 9/82 (10%) Frame = +1 Query: 214 RGHVADVYQISWSADSR-LLLSGSKDSTLKVWDIRAR-------KLKQDLPGHADEVYAV 369 RGH + Y +SW+++ + LLS S D T+ +WDI A K GH+ V V Sbjct: 172 RGHQKEGYGLSWNSNLKGHLLSASDDHTVCLWDISAGPKEGKIVDAKAIFTGHSAVVEDV 231 Query: 370 DWSPDGEKVV-SGGKDRALKLW 432 W E + S D+ L +W Sbjct: 232 AWHLLHESLFGSVADDQKLMIW 253
>APAF_BRARE (Q9I9H8) Apoptotic protease-activating factor 1 (Apaf-1)| Length = 1261 Score = 75.5 bits (184), Expect = 1e-13 Identities = 46/139 (33%), Positives = 76/139 (54%), Gaps = 2/139 (1%) Frame = +1 Query: 22 GSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKF 201 GS+D T+ + E SK +++GH K V+H F+ D + L ++S D ++++W TG+ Sbjct: 984 GSEDGTVQVIEVPSSKA-SVKLSGHTKTVHHCQFTDDCEILITSSEDSTIRVWKWRTGEC 1042 Query: 202 VTAFRGHVADV--YQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDW 375 + +GH+ V + + S+ S L S S D T+KVWD+ ++ QDL H V + D Sbjct: 1043 M-VLQGHMEPVRKFHLLSSSSSPHLFSWSFDGTVKVWDLTRGQMLQDLVCHEGAVLSCDV 1101 Query: 376 SPDGEKVVSGGKDRALKLW 432 S DG + +R K+W Sbjct: 1102 SSDGRLFATTSANRTAKVW 1120 Score = 60.5 bits (145), Expect = 4e-09 Identities = 41/142 (28%), Positives = 70/142 (49%), Gaps = 2/142 (1%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVN--HVYFSPDGQWLASASFDKSVKLWNG 186 L++ S+D T+ +W+ + + GH + V H+ S L S SFD +VK+W+ Sbjct: 1023 LITSSEDSTIRVWKWRTGECMV--LQGHMEPVRKFHLLSSSSSPHLFSWSFDGTVKVWDL 1080 Query: 187 ITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYA 366 G+ + H V S+D RL + S + T KVW + K+ L GH D V + Sbjct: 1081 TRGQMLQDLVCHEGAVLSCDVSSDGRLFATTSANRTAKVWSSASWKMLFLLEGHKDCVRS 1140 Query: 367 VDWSPDGEKVVSGGKDRALKLW 432 +S D +++ +G + ++LW Sbjct: 1141 CRFSWDNKRLATGDDNGEIRLW 1162 Score = 58.2 bits (139), Expect = 2e-08 Identities = 48/189 (25%), Positives = 77/189 (40%), Gaps = 53/189 (28%) Frame = +1 Query: 25 SDDFTMF-LWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKL-------- 177 +D FT LW P K + M GH + VNH FSP+ +LA++S D S+KL Sbjct: 724 NDKFTNTRLWNPN-KKTSQNTMFGHMEPVNHCCFSPNDLYLATSSSDGSLKLFEVSSANE 782 Query: 178 WNGIT--GKFVTAFRGHVADVYQISWSADSRLLLSGSKDS-------------------- 291 W I F + A V +WSAD ++ ++++ Sbjct: 783 WKSIDVDSFFPESDEEIKAMVKCSTWSADGSQIICAARNTVFVFDVETSDLLLKLKTSRL 842 Query: 292 ----------------------TLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSG 405 T+++W+ + K K + GH V+ V +SPDG ++S Sbjct: 843 STIQFCHACPNSSLLAVALSHYTVELWNFESSKKKAECSGHLSWVHCVQFSPDGSLLLSS 902 Query: 406 GKDRALKLW 432 D+ ++LW Sbjct: 903 SDDQTIRLW 911 Score = 53.9 bits (128), Expect = 4e-07 Identities = 41/173 (23%), Positives = 73/173 (42%), Gaps = 40/173 (23%) Frame = +1 Query: 34 FTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLW----------- 180 +T+ LW SK+ KA +GH V+ V FSPDG L S+S D++++LW Sbjct: 864 YTVELWNFESSKK-KAECSGHLSWVHCVQFSPDGSLLLSSSDDQTIRLWETDRVHTSSAV 922 Query: 181 -----------------------------NGITGKFVTAFRGHVADVYQISWSADSRLLL 273 +G TG V + + S ++ + Sbjct: 923 ALKRDTDVLSSHSDATIIAPDSSNRLQVLSGSTGAVVLESEELSSRIRCSCISRNAAFVA 982 Query: 274 SGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 GS+D T++V ++ + K L GH V+ ++ D E +++ +D +++W Sbjct: 983 LGSEDGTVQVIEVPSSKASVKLSGHTKTVHHCQFTDDCEILITSSEDSTIRVW 1035 Score = 49.7 bits (117), Expect = 7e-06 Identities = 37/132 (28%), Positives = 61/132 (46%), Gaps = 9/132 (6%) Frame = +1 Query: 37 TMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFR 216 T+F+++ S T + + P+ LA A +V+LWN + K Sbjct: 822 TVFVFDVETSDLLLKLKTSRLSTIQFCHACPNSSLLAVALSHYTVELWNFESSKKKAECS 881 Query: 217 GHVADVYQISWSADSRLLLSGSKDSTLKVWDI------RARKLKQD---LPGHADEVYAV 369 GH++ V+ + +S D LLLS S D T+++W+ A LK+D L H+D Sbjct: 882 GHLSWVHCVQFSPDGSLLLSSSDDQTIRLWETDRVHTSSAVALKRDTDVLSSHSDATIIA 941 Query: 370 DWSPDGEKVVSG 405 S + +V+SG Sbjct: 942 PDSSNRLQVLSG 953 Score = 46.6 bits (109), Expect = 6e-05 Identities = 36/139 (25%), Positives = 63/139 (45%), Gaps = 9/139 (6%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 L S S D T+ +W+ T Q + H+ V S DG+ A+ S +++ K+W+ + Sbjct: 1066 LFSWSFDGTVKVWDLTRG-QMLQDLVCHEGAVLSCDVSSDGRLFATTSANRTAKVWSSAS 1124 Query: 193 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPG--------- 345 K + GH V +S D++ L +G + +++W + L + P Sbjct: 1125 WKMLFLLEGHKDCVRSCRFSWDNKRLATGDDNGEIRLWSMLDGALLKICPRDTKDSMNSY 1184 Query: 346 HADEVYAVDWSPDGEKVVS 402 HA V + +SPD +VS Sbjct: 1185 HAGWVTDLHFSPDNRVLVS 1203 Score = 46.2 bits (108), Expect = 7e-05 Identities = 30/121 (24%), Positives = 57/121 (47%), Gaps = 5/121 (4%) Frame = +1 Query: 85 MTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFR-GHVADVYQISWSADS 261 + H++ V FSPD + +A+ + D+ VKLWN G + F H + ++ Sbjct: 655 LQAHEEDVLCCAFSPDDRHIATCASDRKVKLWNVERGVLIREFEVEHEEQINHCQFTNTG 714 Query: 262 RLLL----SGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKL 429 R +L S K + ++W+ + + + GH + V +SP+ + + D +LKL Sbjct: 715 RRVLLATCSNDKFTNTRLWNPNKKTSQNTMFGHMEPVNHCCFSPNDLYLATSSSDGSLKL 774 Query: 430 W 432 + Sbjct: 775 F 775 Score = 38.5 bits (88), Expect = 0.016 Identities = 27/105 (25%), Positives = 50/105 (47%), Gaps = 2/105 (1%) Frame = +1 Query: 124 SPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKV 303 S + ++A S D +V++ + K GH V+ ++ D +L++ S+DST++V Sbjct: 975 SRNAAFVALGSEDGTVQVIEVPSSKASVKLSGHTKTVHHCQFTDDCEILITSSEDSTIRV 1034 Query: 304 WDIRARKLKQDLPGHADEV--YAVDWSPDGEKVVSGGKDRALKLW 432 W R + L GH + V + + S + S D +K+W Sbjct: 1035 WKWRTGEC-MVLQGHMEPVRKFHLLSSSSSPHLFSWSFDGTVKVW 1078 Score = 37.4 bits (85), Expect = 0.035 Identities = 19/71 (26%), Positives = 32/71 (45%) Frame = +1 Query: 220 HVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVV 399 H VY +S D + S L+V+ + + +L H ++V +SPD + Sbjct: 616 HQGAVYYACFSKDGSKIASCGASKALRVFKSTSGEKLLELQAHEEDVLCCAFSPDDRHIA 675 Query: 400 SGGKDRALKLW 432 + DR +KLW Sbjct: 676 TCASDRKVKLW 686
>UTP13_YEAST (Q05946) U3 small nucleolar RNA-associated protein 13 (U3| snoRNA-associated protein 13) Length = 817 Score = 75.5 bits (184), Expect = 1e-13 Identities = 42/152 (27%), Positives = 76/152 (50%), Gaps = 9/152 (5%) Frame = +1 Query: 4 PXRLVSGSDDFTMFLW---EPTIS------KQPKARMTGHQKVVNHVYFSPDGQWLASAS 156 P L++ S+D T+ W +PT S K + H+K +N + SP+ A+AS Sbjct: 451 PEFLLTASNDLTIKKWIIPKPTASMDVQIIKVSEYTRHAHEKDINALSVSPNDSIFATAS 510 Query: 157 FDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQD 336 +DK+ K+WN G+ H ++ +S+ +LL + S D T+K+W + + + Sbjct: 511 YDKTCKIWNLENGELEATLANHKRGLWDVSFCQYDKLLATSSGDKTVKIWSLDTFSVMKT 570 Query: 337 LPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 L GH + V + ++++S G D +K+W Sbjct: 571 LEGHTNAVQRCSFINKQKQLISCGADGLIKIW 602 Score = 64.3 bits (155), Expect = 3e-10 Identities = 37/138 (26%), Positives = 69/138 (50%) Frame = +1 Query: 19 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 198 + S D T +W + + +A + H++ + V F + LA++S DK+VK+W+ T Sbjct: 508 TASYDKTCKIWNLE-NGELEATLANHKRGLWDVSFCQYDKLLATSSGDKTVKIWSLDTFS 566 Query: 199 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWS 378 + GH V + S+ + L+S D +K+WD + + + L GH + ++A+ Sbjct: 567 VMKTLEGHTNAVQRCSFINKQKQLISCGADGLIKIWDCSSGECLKTLDGHNNRLWALSTM 626 Query: 379 PDGEKVVSGGKDRALKLW 432 DG+ +VS D + W Sbjct: 627 NDGDMIVSADADGVFQFW 644 Score = 45.1 bits (105), Expect = 2e-04 Identities = 32/133 (24%), Positives = 53/133 (39%), Gaps = 19/133 (14%) Frame = +1 Query: 91 GHQKVVNHVYFSPDGQWLASASFDKSVKLW----NGITGKFVTAFRGHVADVYQISW--- 249 GH+ ++N + + DG W+A+AS D + +W N + GH A V + Sbjct: 386 GHEDLLNSLDATEDGLWIATASKDNTAIVWRYNENSCKFDIYAKYIGHSAAVTAVGLPNI 445 Query: 250 --SADSRLLLSGSKDSTLKVWDIRARKLKQDLP----------GHADEVYAVDWSPDGEK 393 LL+ S D T+K W I D+ H ++ A+ SP+ Sbjct: 446 VSKGYPEFLLTASNDLTIKKWIIPKPTASMDVQIIKVSEYTRHAHEKDINALSVSPNDSI 505 Query: 394 VVSGGKDRALKLW 432 + D+ K+W Sbjct: 506 FATASYDKTCKIW 518 Score = 38.5 bits (88), Expect = 0.016 Identities = 36/163 (22%), Positives = 64/163 (39%), Gaps = 51/163 (31%) Frame = +1 Query: 97 QKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVT----------------------- 207 ++ + + +PDGQ+L S + +K+++ TGK V Sbjct: 61 EQEITALKLTPDGQYLTYVSQAQLLKIFHLKTGKVVRSMKISSPSYILDADSTSTLLAVG 120 Query: 208 ------------------AFRGHVADVYQISW----SADSRLLLSGSKDSTLKVWDIRAR 321 +F+GH + + + ++ LL SG + +KVWD+ R Sbjct: 121 GTDGSIIVVDIENGYITHSFKGHGGTISSLKFYGQLNSKIWLLASGDTNGMVKVWDLVKR 180 Query: 322 KLKQDLPGHADEVYAVD--WSPDGEK----VVSGGKDRALKLW 432 K L H V +D PD ++ ++SGG+D + LW Sbjct: 181 KCLHTLQEHTSAVRGLDIIEVPDNDEPSLNLLSGGRDDIINLW 223 Score = 31.6 bits (70), Expect = 1.9 Identities = 18/67 (26%), Positives = 34/67 (50%), Gaps = 6/67 (8%) Frame = +1 Query: 142 LASASFDKSVKLWNGITGKFVTAFRGHVA-----DVYQISWSADSRL-LLSGSKDSTLKV 303 LAS + VK+W+ + K + + H + D+ ++ + + L LLSG +D + + Sbjct: 163 LASGDTNGMVKVWDLVKRKCLHTLQEHTSAVRGLDIIEVPDNDEPSLNLLSGGRDDIINL 222 Query: 304 WDIRARK 324 WD +K Sbjct: 223 WDFNMKK 229
>GBB1_CRIGR (Q6TMK6) Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta| subunit 1 (Transducin beta chain 1) Length = 339 Score = 75.5 bits (184), Expect = 1e-13 Identities = 37/116 (31%), Positives = 64/116 (55%) Frame = +1 Query: 85 MTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSR 264 + GH ++ F D Q + ++S D + LW+ TG+ T F GH DV +S + D+R Sbjct: 138 LAGHTGYLSCCRFLNDNQ-IVTSSEDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTR 196 Query: 265 LLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 L +SG+ D++ K+WD+R +Q GH ++ A+ + P+G +G D +L+ Sbjct: 197 LFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLF 252 Score = 62.4 bits (150), Expect = 1e-09 Identities = 40/146 (27%), Positives = 72/146 (49%), Gaps = 5/146 (3%) Frame = +1 Query: 10 RLVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGI 189 ++V+ S+D T LW+ +Q TGH V + +PD + S + D S KLW+ Sbjct: 155 QIVTSSEDTTCALWDIETGQQTTT-FTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVR 213 Query: 190 TGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADE---- 357 G F GH +D+ I + + +GS D+T +++D+RA Q+L ++ + Sbjct: 214 EGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRA---DQELMTYSHDNIIC 270 Query: 358 -VYAVDWSPDGEKVVSGGKDRALKLW 432 + +V +S G +++G D +W Sbjct: 271 GITSVSFSKSGRLLLAGYDDFNCNVW 296 Score = 61.6 bits (148), Expect = 2e-09 Identities = 40/141 (28%), Positives = 66/141 (46%), Gaps = 2/141 (1%) Frame = +1 Query: 16 VSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITG 195 VSG+ D + LW+ + TGH+ +N + F P+G A+ S D + +L++ Sbjct: 199 VSGACDASAKLWDVR-EGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRAD 257 Query: 196 KFVTAFRGH--VADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAV 369 + + + + + +S+S RLLL+G D VWD L GH + V + Sbjct: 258 QELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDNRVSCL 317 Query: 370 DWSPDGEKVVSGGKDRALKLW 432 + DG V +G D LK+W Sbjct: 318 GVTDDGMAVATGSWDSFLKIW 338 Score = 54.3 bits (129), Expect = 3e-07 Identities = 25/73 (34%), Positives = 37/73 (50%) Frame = +1 Query: 214 RGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEK 393 RGH+A +Y + W DSRLL+S S+D L +WD +P + V ++P G Sbjct: 51 RGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNY 110 Query: 394 VVSGGKDRALKLW 432 V GG D ++ Sbjct: 111 VACGGLDNICSIY 123 Score = 40.8 bits (94), Expect = 0.003 Identities = 35/170 (20%), Positives = 62/170 (36%), Gaps = 46/170 (27%) Frame = +1 Query: 61 ISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT---------------- 192 I + + + GH + +++ D + L SAS D + +W+ T Sbjct: 42 IQMRTRRTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMT 101 Query: 193 ------GKFVTA------------------------FRGHVADVYQISWSADSRLLLSGS 282 G +V GH + + D++++ S S Sbjct: 102 CAYAPSGNYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLNDNQIVTS-S 160 Query: 283 KDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 +D+T +WDI + GH +V ++ +PD VSG D + KLW Sbjct: 161 EDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLW 210 Score = 36.6 bits (83), Expect = 0.059 Identities = 25/100 (25%), Positives = 44/100 (44%), Gaps = 3/100 (3%) Frame = +1 Query: 19 SGSDDFTMFLWEPTISKQPKARMTGHQKVV---NHVYFSPDGQWLASASFDKSVKLWNGI 189 +GSDD T L++ + + H ++ V FS G+ L + D + +W+ + Sbjct: 242 TGSDDATCRLFD--LRADQELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDAL 299 Query: 190 TGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWD 309 GH V + + D + +GS DS LK+W+ Sbjct: 300 KADRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN 339
>GBB_LYMST (Q08706) Guanine nucleotide-binding protein beta subunit| Length = 341 Score = 75.1 bits (183), Expect = 2e-13 Identities = 38/116 (32%), Positives = 62/116 (53%) Frame = +1 Query: 85 MTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSR 264 + GH ++ F D + ++S D S LW+ TG+ T+F GH DV +S S D R Sbjct: 140 LPGHTGYLSCCRFIDDNS-IVTSSGDMSCALWDIETGQQTTSFTGHTGDVMSLSTSPDFR 198 Query: 265 LLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 +SG+ D++ K+WD+R KQ GH ++ A+ + P+G +G D +L+ Sbjct: 199 TFVSGACDASAKLWDVRDGMCKQTFSGHESDINAITYFPNGHAFATGSDDATCRLF 254 Score = 61.6 bits (148), Expect = 2e-09 Identities = 48/184 (26%), Positives = 75/184 (40%), Gaps = 44/184 (23%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 +V+ S D + LW+ +Q + TGH V + SPD + S + D S KLW+ Sbjct: 158 IVTSSGDMSCALWDIETGQQTTS-FTGHTGDVMSLSTSPDFRTFVSGACDASAKLWDVRD 216 Query: 193 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARK---------------- 324 G F GH +D+ I++ + +GS D+T +++DIRA + Sbjct: 217 GMCKQTFSGHESDINAITYFPNGHAFATGSDDATCRLFDIRADQEIGMYSHDNIICGITS 276 Query: 325 ------------------------LKQD----LPGHADEVYAVDWSPDGEKVVSGGKDRA 420 LKQ+ L GH + V + + DG V +G D Sbjct: 277 VAFSKSGRLLLGRYDDFNCNVWDVLKQETHGVLAGHDNRVSCLGVTEDGSAVATGSWDSF 336 Query: 421 LKLW 432 LK+W Sbjct: 337 LKIW 340 Score = 51.6 bits (122), Expect = 2e-06 Identities = 25/73 (34%), Positives = 38/73 (52%) Frame = +1 Query: 214 RGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEK 393 RGH+A +Y + W++DSR L+S S+D L VWD +P + V ++P G Sbjct: 53 RGHLAKIYAMHWASDSRNLVSASQDGKLIVWDGYTTNKVHAIPLRSSWVMTCAYAPSGNF 112 Query: 394 VVSGGKDRALKLW 432 V GG D ++ Sbjct: 113 VACGGLDNICSIY 125 Score = 44.7 bits (104), Expect = 2e-04 Identities = 29/128 (22%), Positives = 58/128 (45%), Gaps = 4/128 (3%) Frame = +1 Query: 61 ISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQ 240 I + + + GH + ++++ D + L SAS D + +W+G T V A + V Sbjct: 44 IQMRTRRTLRGHLAKIYAMHWASDSRNLVSASQDGKLIVWDGYTTNKVHAIPLRSSWVMT 103 Query: 241 ISWSADSRLLLSGSKDSTLKVWDIRAR----KLKQDLPGHADEVYAVDWSPDGEKVVSGG 408 +++ + G D+ ++ ++ R ++ ++LPGH + + D V S G Sbjct: 104 CAYAPSGNFVACGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFIDDNSIVTSSG 163 Query: 409 KDRALKLW 432 D + LW Sbjct: 164 -DMSCALW 170 Score = 37.0 bits (84), Expect = 0.045 Identities = 27/100 (27%), Positives = 45/100 (45%), Gaps = 3/100 (3%) Frame = +1 Query: 19 SGSDDFTMFLWEPTISKQPKARMTGHQKVV---NHVYFSPDGQWLASASFDKSVKLWNGI 189 +GSDD T L++ I + M H ++ V FS G+ L D + +W+ + Sbjct: 244 TGSDDATCRLFD--IRADQEIGMYSHDNIICGITSVAFSKSGRLLLGRYDDFNCNVWDVL 301 Query: 190 TGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWD 309 + GH V + + D + +GS DS LK+W+ Sbjct: 302 KQETHGVLAGHDNRVSCLGVTEDGSAVATGSWDSFLKIWN 341
>PEX7_MOUSE (P97865) Peroxisomal targeting signal 2 receptor (PTS2 receptor)| (Peroxin-7) Length = 318 Score = 75.1 bits (183), Expect = 2e-13 Identities = 45/144 (31%), Positives = 73/144 (50%), Gaps = 4/144 (2%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDG--QWLASASFDKSVKLWNG 186 LV+ S D ++ LW+ + P H + V V +S Q + S S+D++VK+W+ Sbjct: 78 LVTCSGDGSLQLWDTAKATGPLQVYKEHTQEVYSVDWSQTRGEQLVVSGSWDQTVKVWDP 137 Query: 187 ITGKFVTAFRGHVADVYQISWSAD-SRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVY 363 G + FRGH + +Y WS S S D TL++WD++ ++ +P H E+ Sbjct: 138 TVGNSLCTFRGHESVIYSTIWSPHIPGCFASASGDQTLRIWDVKTTGVRIVIPAHQTEIL 197 Query: 364 AVDWSPDGEK-VVSGGKDRALKLW 432 + DW E VV+G D +L+ W Sbjct: 198 SCDWCKYNENLVVTGAVDCSLRGW 221 Score = 38.5 bits (88), Expect = 0.016 Identities = 20/58 (34%), Positives = 32/58 (55%), Gaps = 1/58 (1%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSP-DGQWLASASFDKSVKLWN 183 +V+G+ D ++ W+ +QP + GH + V FSP LAS S+D +V+ WN Sbjct: 209 VVTGAVDCSLRGWDLRNVRQPVFELLGHTYAIRRVKFSPFHASVLASCSYDFTVRFWN 266
>PEX7_CRIGR (Q8R537) Peroxisomal targeting signal 2 receptor (PTS2 receptor)| (Peroxin-7) Length = 318 Score = 75.1 bits (183), Expect = 2e-13 Identities = 45/144 (31%), Positives = 73/144 (50%), Gaps = 4/144 (2%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDG--QWLASASFDKSVKLWNG 186 LV+ S D ++ LW+ + P H + V V +S Q + S S+D++VK+W+ Sbjct: 78 LVTCSGDGSLQLWDTAKATGPLQVYKEHTQEVYSVDWSQTRGEQLVVSGSWDQTVKVWDP 137 Query: 187 ITGKFVTAFRGHVADVYQISWSAD-SRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVY 363 G + FRGH + +Y WS S S D TL++WD++ ++ +P H E+ Sbjct: 138 TVGNSLCTFRGHESVIYSTIWSPHIPGCFASASGDQTLRIWDVKTAGVRIVIPAHQTEIL 197 Query: 364 AVDWSPDGEK-VVSGGKDRALKLW 432 + DW E VV+G D +L+ W Sbjct: 198 SCDWCKYNENLVVTGAVDCSLRGW 221 Score = 38.5 bits (88), Expect = 0.016 Identities = 20/58 (34%), Positives = 32/58 (55%), Gaps = 1/58 (1%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSP-DGQWLASASFDKSVKLWN 183 +V+G+ D ++ W+ +QP + GH + V FSP LAS S+D +V+ WN Sbjct: 209 VVTGAVDCSLRGWDLRNVRQPVFELLGHTYAIRRVKFSPFHASVLASCSYDFTVRFWN 266
>TUP1_YEAST (P16649) Glucose repression regulatory protein TUP1 (Flocculation| suppressor protein) (Repressor AER2) Length = 713 Score = 75.1 bits (183), Expect = 2e-13 Identities = 38/110 (34%), Positives = 64/110 (58%), Gaps = 1/110 (0%) Frame = +1 Query: 106 VNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSK 285 + V FSPDG++LA+ + D+ +++W+ K V +GH D+Y + + L+SGS Sbjct: 446 IRSVCFSPDGKFLATGAEDRLIRIWDIENRKIVMILQGHEQDIYSLDYFPSGDKLVSGSG 505 Query: 286 DSTLKVWDIRARKLKQDLPGHADEVYAVDWSP-DGEKVVSGGKDRALKLW 432 D T+++WD+R + L D V V SP DG+ + +G DRA+++W Sbjct: 506 DRTVRIWDLRTGQCSLTL-SIEDGVTTVAVSPGDGKYIAAGSLDRAVRVW 554 Score = 71.2 bits (173), Expect = 2e-12 Identities = 45/160 (28%), Positives = 79/160 (49%), Gaps = 19/160 (11%) Frame = +1 Query: 10 RLVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGI 189 +LVSGS D T+ +W+ + Q ++ V DG+++A+ S D++V++W+ Sbjct: 499 KLVSGSGDRTVRIWD-LRTGQCSLTLSIEDGVTTVAVSPGDGKYIAAGSLDRAVRVWDSE 557 Query: 190 TGKFVTAF-------RGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLP-- 342 TG V GH VY + ++ D + ++SGS D ++K+W+++ K D Sbjct: 558 TGFLVERLDSENESGTGHKDSVYSVVFTRDGQSVVSGSLDRSVKLWNLQNANNKSDSKTP 617 Query: 343 ----------GHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 GH D V +V + + E ++SG KDR + W Sbjct: 618 NSGTCEVTYIGHKDFVLSVATTQNDEYILSGSKDRGVLFW 657 Score = 66.6 bits (161), Expect = 5e-11 Identities = 26/71 (36%), Positives = 48/71 (67%), Gaps = 2/71 (2%) Frame = +1 Query: 226 ADVY--QISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVV 399 +D+Y + +S D + L +G++D +++WDI RK+ L GH ++Y++D+ P G+K+V Sbjct: 442 SDLYIRSVCFSPDGKFLATGAEDRLIRIWDIENRKIVMILQGHEQDIYSLDYFPSGDKLV 501 Query: 400 SGGKDRALKLW 432 SG DR +++W Sbjct: 502 SGSGDRTVRIW 512 Score = 58.5 bits (140), Expect = 1e-08 Identities = 47/159 (29%), Positives = 68/159 (42%), Gaps = 18/159 (11%) Frame = +1 Query: 10 RLVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWN-- 183 R V D T FL E S+ TGH+ V V F+ DGQ + S S D+SVKLWN Sbjct: 549 RAVRVWDSETGFLVERLDSENESG--TGHKDSVYSVVFTRDGQSVVSGSLDRSVKLWNLQ 606 Query: 184 ----------GITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQ 333 +G + GH V ++ + + +LSGSKD + WD ++ Sbjct: 607 NANNKSDSKTPNSGTCEVTYIGHKDFVLSVATTQNDEYILSGSKDRGVLFWDKKSGNPLL 666 Query: 334 DLPGHADEVYAV------DWSPDGEKVVSGGKDRALKLW 432 L GH + V +V P+ +G D ++W Sbjct: 667 MLQGHRNSVISVAVANGSPLGPEYNVFATGSGDCKARIW 705
>GBB1_XENLA (P79959) Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta| subunit 1 (Transducin beta chain 1) (XGbeta1) Length = 340 Score = 74.7 bits (182), Expect = 2e-13 Identities = 37/116 (31%), Positives = 62/116 (53%) Frame = +1 Query: 85 MTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSR 264 + GH ++ F D Q + S+ D + LW+ TG+ T F GH DV +S + DSR Sbjct: 139 LAGHTGYLSCCRFLDDNQIITSSG-DTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDSR 197 Query: 265 LLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 +SG+ D++ K+WD+R +Q GH ++ A+ + P+G +G D +L+ Sbjct: 198 CFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLF 253 Score = 60.8 bits (146), Expect = 3e-09 Identities = 40/141 (28%), Positives = 66/141 (46%), Gaps = 2/141 (1%) Frame = +1 Query: 16 VSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITG 195 VSG+ D + LW+ + TGH+ +N + F P+G A+ S D + +L++ Sbjct: 200 VSGACDASAKLWDVR-EGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRAD 258 Query: 196 K--FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAV 369 + V + + + +++S RLLL+G D VWD L GH + V + Sbjct: 259 QELMVYSHDNIICGITSVAFSKSGRLLLAGYDDFNCNVWDTLKADRAGVLAGHDNRVSCL 318 Query: 370 DWSPDGEKVVSGGKDRALKLW 432 + DG V +G D LK+W Sbjct: 319 GVTDDGMAVATGSWDSFLKIW 339 Score = 60.5 bits (145), Expect = 4e-09 Identities = 39/146 (26%), Positives = 71/146 (48%), Gaps = 5/146 (3%) Frame = +1 Query: 10 RLVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGI 189 ++++ S D T LW+ +Q TGH V + +PD + S + D S KLW+ Sbjct: 156 QIITSSGDTTCALWDIETGQQTTT-FTGHTGDVMSLSLAPDSRCFVSGACDASAKLWDVR 214 Query: 190 TGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADE---- 357 G F GH +D+ I + + +GS D+T +++D+RA Q+L ++ + Sbjct: 215 EGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRA---DQELMVYSHDNIIC 271 Query: 358 -VYAVDWSPDGEKVVSGGKDRALKLW 432 + +V +S G +++G D +W Sbjct: 272 GITSVAFSKSGRLLLAGYDDFNCNVW 297 Score = 53.9 bits (128), Expect = 4e-07 Identities = 25/73 (34%), Positives = 37/73 (50%) Frame = +1 Query: 214 RGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEK 393 RGH+A +Y + W DSRLL+S S+D L +WD +P + V ++P G Sbjct: 52 RGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNY 111 Query: 394 VVSGGKDRALKLW 432 V GG D ++ Sbjct: 112 VACGGLDNICPIY 124 Score = 41.2 bits (95), Expect = 0.002 Identities = 33/169 (19%), Positives = 59/169 (34%), Gaps = 45/169 (26%) Frame = +1 Query: 61 ISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAF--------- 213 I + + + GH + +++ D + L SAS D + +W+ T V A Sbjct: 43 IQMRTRRTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMT 102 Query: 214 --------------RGHVADVYQISWS----------------------ADSRLLLSGSK 285 ++ +Y + D +++ S Sbjct: 103 CAYAPSGNYVACGGLDNICPIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIITSSG 162 Query: 286 DSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 D+T +WDI + GH +V ++ +PD VSG D + KLW Sbjct: 163 DTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDSRCFVSGACDASAKLW 211 Score = 36.6 bits (83), Expect = 0.059 Identities = 25/100 (25%), Positives = 45/100 (45%), Gaps = 3/100 (3%) Frame = +1 Query: 19 SGSDDFTMFLWEPTISKQPKARMTGHQKVV---NHVYFSPDGQWLASASFDKSVKLWNGI 189 +GSDD T L++ + + + H ++ V FS G+ L + D + +W+ + Sbjct: 243 TGSDDATCRLFD--LRADQELMVYSHDNIICGITSVAFSKSGRLLLAGYDDFNCNVWDTL 300 Query: 190 TGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWD 309 GH V + + D + +GS DS LK+W+ Sbjct: 301 KADRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN 340
>GBB1_HOMAM (O45040) Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta| subunit 1 (Transducin beta chain 1) Length = 340 Score = 74.7 bits (182), Expect = 2e-13 Identities = 39/116 (33%), Positives = 62/116 (53%) Frame = +1 Query: 85 MTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSR 264 + GH ++ F D Q + ++S D + LW+ TG+ T F GH DV +S S + R Sbjct: 139 LPGHTGYLSCCRFVDDNQ-IVTSSGDMTCALWDIETGQQCTQFTGHTGDVMSLSLSPNMR 197 Query: 265 LLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 SG+ D++ K+WDIR +Q PGH ++ AV + P+G +G D +L+ Sbjct: 198 TFTSGACDASAKLWDIRDGMCRQTFPGHESDINAVTFFPNGHAFATGSDDATCRLF 253 Score = 60.8 bits (146), Expect = 3e-09 Identities = 40/146 (27%), Positives = 74/146 (50%), Gaps = 5/146 (3%) Frame = +1 Query: 10 RLVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGI 189 ++V+ S D T LW+ +Q + TGH V + SP+ + S + D S KLW+ Sbjct: 156 QIVTSSGDMTCALWDIETGQQC-TQFTGHTGDVMSLSLSPNMRTFTSGACDASAKLWDIR 214 Query: 190 TGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADE---- 357 G F GH +D+ +++ + +GS D+T +++DIRA Q+L ++ + Sbjct: 215 DGMCRQTFPGHESDINAVTFFPNGHAFATGSDDATCRLFDIRA---DQELAMYSHDNIIC 271 Query: 358 -VYAVDWSPDGEKVVSGGKDRALKLW 432 + +V +S G+ +++G D +W Sbjct: 272 GITSVAFSKSGKLLLAGYDDFNCNVW 297 Score = 58.5 bits (140), Expect = 1e-08 Identities = 42/143 (29%), Positives = 67/143 (46%), Gaps = 5/143 (3%) Frame = +1 Query: 19 SGSDDFTMFLWEPTISKQPKARMT--GHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 SG+ D + LW+ + R T GH+ +N V F P+G A+ S D + +L++ I Sbjct: 201 SGACDASAKLWD---IRDGMCRQTFPGHESDINAVTFFPNGHAFATGSDDATCRLFD-IR 256 Query: 193 GKFVTAFRGH---VADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVY 363 A H + + +++S +LLL+G D VWD + L GH + V Sbjct: 257 ADQELAMYSHDNIICGITSVAFSKSGKLLLAGYDDFNCNVWDSMRTERAGVLAGHDNRVS 316 Query: 364 AVDWSPDGEKVVSGGKDRALKLW 432 + + DG V +G D LK+W Sbjct: 317 CLGVTEDGMAVATGSWDSFLKIW 339 Score = 52.4 bits (124), Expect = 1e-06 Identities = 25/73 (34%), Positives = 37/73 (50%) Frame = +1 Query: 214 RGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEK 393 RGH+A +Y + W +DSR L+S S+D L VWD +P + V ++P G Sbjct: 52 RGHLAKIYAMHWGSDSRNLVSASQDGKLIVWDSYTTNKVHAIPLRSSWVMTCAYAPSGSY 111 Query: 394 VVSGGKDRALKLW 432 V GG D ++ Sbjct: 112 VACGGLDNICSIY 124 Score = 41.6 bits (96), Expect = 0.002 Identities = 28/128 (21%), Positives = 56/128 (43%), Gaps = 4/128 (3%) Frame = +1 Query: 61 ISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQ 240 I + + + GH + +++ D + L SAS D + +W+ T V A + V Sbjct: 43 IQMRTRRTLRGHLAKIYAMHWGSDSRNLVSASQDGKLIVWDSYTTNKVHAIPLRSSWVMT 102 Query: 241 ISWSADSRLLLSGSKDSTLKVWDIRAR----KLKQDLPGHADEVYAVDWSPDGEKVVSGG 408 +++ + G D+ ++ ++ R ++ ++LPGH + + D + V S G Sbjct: 103 CAYAPSGSYVACGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFVDDNQIVTSSG 162 Query: 409 KDRALKLW 432 D LW Sbjct: 163 -DMTCALW 169 Score = 39.7 bits (91), Expect = 0.007 Identities = 27/100 (27%), Positives = 46/100 (46%), Gaps = 3/100 (3%) Frame = +1 Query: 19 SGSDDFTMFLWEPTISKQPKARMTGHQKVV---NHVYFSPDGQWLASASFDKSVKLWNGI 189 +GSDD T L++ I + M H ++ V FS G+ L + D + +W+ + Sbjct: 243 TGSDDATCRLFD--IRADQELAMYSHDNIICGITSVAFSKSGKLLLAGYDDFNCNVWDSM 300 Query: 190 TGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWD 309 + GH V + + D + +GS DS LK+W+ Sbjct: 301 RTERAGVLAGHDNRVSCLGVTEDGMAVATGSWDSFLKIWN 340
>TB1RB_XENLA (Q6GPC6) F-box-like/WD-repeat-containing protein TBL1XR1-B| (Transducin beta-like 1X-related homolog 1-B) (Nuclear receptor corepressor/HDAC3 complex subunit TBLR1-B) (TBL1-related protein 1-B) Length = 522 Score = 74.7 bits (182), Expect = 2e-13 Identities = 41/130 (31%), Positives = 64/130 (49%), Gaps = 9/130 (6%) Frame = +1 Query: 70 QPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISW 249 +P GH VN + + P G LAS S D ++K+W+ V + H ++Y I W Sbjct: 348 RPIKTFQGHTNEVNAIKWDPTGNLLASCSDDMTLKIWSMKHDTCVHDLQAHNKEIYTIKW 407 Query: 250 SAD---------SRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVS 402 S + +L S S DST+++WD+ L H + VY+V +SPDG + S Sbjct: 408 SPTGPGTNNPNANLMLASASFDSTVRLWDVDRGICIHTLTKHQEPVYSVAFSPDGRYLAS 467 Query: 403 GGKDRALKLW 432 G D+ + +W Sbjct: 468 GSFDKCVHIW 477 Score = 65.9 bits (159), Expect = 9e-11 Identities = 38/101 (37%), Positives = 58/101 (57%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 L S S D T+ LW+ +T HQ+ V V FSPDG++LAS SFDK V +WN T Sbjct: 423 LASASFDSTVRLWDVDRGICIHT-LTKHQEPVYSVAFSPDGRYLASGSFDKCVHIWNTQT 481 Query: 193 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIR 315 G V ++RG ++++ W+A + + + D ++ V D+R Sbjct: 482 GALVHSYRG-TGGIFEVCWNAAGDKVGASASDGSVCVLDLR 521 Score = 64.3 bits (155), Expect = 3e-10 Identities = 43/143 (30%), Positives = 65/143 (45%), Gaps = 9/143 (6%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQ---------WLASASFDK 165 L S SDD T+ +W + H K + + +SP G LASASFD Sbjct: 372 LASCSDDMTLKIWSMKHDTCVHD-LQAHNKEIYTIKWSPTGPGTNNPNANLMLASASFDS 430 Query: 166 SVKLWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPG 345 +V+LW+ G + H VY +++S D R L SGS D + +W+ + L G Sbjct: 431 TVRLWDVDRGICIHTLTKHQEPVYSVAFSPDGRYLASGSFDKCVHIWNTQTGALVHSYRG 490 Query: 346 HADEVYAVDWSPDGEKVVSGGKD 414 ++ V W+ G+KV + D Sbjct: 491 -TGGIFEVCWNAAGDKVGASASD 512 Score = 59.7 bits (143), Expect = 7e-09 Identities = 39/149 (26%), Positives = 62/149 (41%), Gaps = 9/149 (6%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 ++S D T +W+ + K + H V + + + AS S D + + Sbjct: 289 ILSAGVDKTTIIWDAHTG-EAKQQFPFHSAPALDVDWQSNNTF-ASCSTDMCIHVCKLGQ 346 Query: 193 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVD 372 + + F+GH +V I W LL S S D TLK+W ++ DL H E+Y + Sbjct: 347 DRPIKTFQGHTNEVNAIKWDPTGNLLASCSDDMTLKIWSMKHDTCVHDLQAHNKEIYTIK 406 Query: 373 WSPDGE---------KVVSGGKDRALKLW 432 WSP G + S D ++LW Sbjct: 407 WSPTGPGTNNPNANLMLASASFDSTVRLW 435 Score = 57.4 bits (137), Expect = 3e-08 Identities = 36/140 (25%), Positives = 63/140 (45%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 L +GS D +W T + + H+ + + ++ G ++ SA DK+ +W+ T Sbjct: 248 LATGSYDGFARIW--TKDGNLASTLGQHKGPIFALKWNKKGNFILSAGVDKTTIIWDAHT 305 Query: 193 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVD 372 G+ F H A + W +++ S S D + V + + + GH +EV A+ Sbjct: 306 GEAKQQFPFHSAPALDVDWQSNN-TFASCSTDMCIHVCKLGQDRPIKTFQGHTNEVNAIK 364 Query: 373 WSPDGEKVVSGGKDRALKLW 432 W P G + S D LK+W Sbjct: 365 WDPTGNLLASCSDDMTLKIW 384 Score = 52.8 bits (125), Expect = 8e-07 Identities = 32/130 (24%), Positives = 57/130 (43%), Gaps = 14/130 (10%) Frame = +1 Query: 85 MTGHQKVVNHVYFSPDGQWLASASFDKSVKLW----NGITGKFVTAFRGHV--------- 225 + GH+ V ++P LAS S D + ++W N +G R + Sbjct: 173 LRGHESEVFICAWNPVSDLLASGSGDSTARIWNLSENSTSGSTQLVLRHCIREGGQDVPS 232 Query: 226 -ADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVS 402 DV + W+++ LL +GS D ++W + L L H ++A+ W+ G ++S Sbjct: 233 NKDVTSLDWNSEGTLLATGSYDGFARIW-TKDGNLASTLGQHKGPIFALKWNKKGNFILS 291 Query: 403 GGKDRALKLW 432 G D+ +W Sbjct: 292 AGVDKTTIIW 301
>FBXW7_HUMAN (Q969H0) F-box/WD-repeat protein 7 (F-box and WD-40 domain protein| 7) (F-box protein FBX30) (hCdc4) (Archipelago homolog) (hAgo) (SEL-10) Length = 707 Score = 74.7 bits (182), Expect = 2e-13 Identities = 48/141 (34%), Positives = 74/141 (52%) Frame = +1 Query: 10 RLVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGI 189 R+VSGSDD T+ +W K + + GH V + + S S D+++K+WN Sbjct: 393 RIVSGSDDNTLKVWSAVTGKCLRT-LVGHTGGVWSSQMRDN--IIISGSTDRTLKVWNAE 449 Query: 190 TGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAV 369 TG+ + GH + V + + ++SGS+D+TL+VWDI + L GH V V Sbjct: 450 TGECIHTLYGHTSTVRCMH--LHEKRVVSGSRDATLRVWDIETGQCLHVLMGHVAAVRCV 507 Query: 370 DWSPDGEKVVSGGKDRALKLW 432 + DG +VVSG D +K+W Sbjct: 508 QY--DGRRVVSGAYDFMVKVW 526 Score = 67.4 bits (163), Expect = 3e-11 Identities = 42/140 (30%), Positives = 73/140 (52%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 ++SGS D T+ +W + + GH V ++ + + S S D ++++W+ T Sbjct: 434 IISGSTDRTLKVWNAETGECIHT-LYGHTSTVRCMHLHE--KRVVSGSRDATLRVWDIET 490 Query: 193 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVD 372 G+ + GHVA V + + D R ++SG+ D +KVWD L GH + VY++ Sbjct: 491 GQCLHVLMGHVAAVRCVQY--DGRRVVSGAYDFMVKVWDPETETCLHTLQGHTNRVYSLQ 548 Query: 373 WSPDGEKVVSGGKDRALKLW 432 + DG VVSG D ++++W Sbjct: 549 F--DGIHVVSGSLDTSIRVW 566 Score = 65.5 bits (158), Expect = 1e-10 Identities = 43/144 (29%), Positives = 73/144 (50%), Gaps = 3/144 (2%) Frame = +1 Query: 10 RLVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGI 189 R+VSG+ DF + +W+P ++ + GH V + F DG + S S D S+++W+ Sbjct: 513 RVVSGAYDFMVKVWDPE-TETCLHTLQGHTNRVYSLQF--DGIHVVSGSLDTSIRVWDVE 569 Query: 190 TGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPG---HADEV 360 TG + GH + +L+SG+ DST+K+WDI+ + Q L G H V Sbjct: 570 TGNCIHTLTGHQS--LTSGMELKDNILVSGNADSTVKIWDIKTGQCLQTLQGPNKHQSAV 627 Query: 361 YAVDWSPDGEKVVSGGKDRALKLW 432 + ++ + V++ D +KLW Sbjct: 628 TCLQFNKN--FVITSSDDGTVKLW 649 Score = 65.1 bits (157), Expect = 2e-10 Identities = 41/130 (31%), Positives = 62/130 (47%), Gaps = 2/130 (1%) Frame = +1 Query: 49 WEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVA 228 W K PK V+ + F G + S S D ++K+W+ +TGK + GH Sbjct: 365 WRRGELKSPKVLKGHDDHVITCLQFC--GNRIVSGSDDNTLKVWSAVTGKCLRTLVGHTG 422 Query: 229 DVYQISWSADSR--LLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVS 402 V WS+ R +++SGS D TLKVW+ + L GH V + ++VVS Sbjct: 423 GV----WSSQMRDNIIISGSTDRTLKVWNAETGECIHTLYGHTSTVRCMHLHE--KRVVS 476 Query: 403 GGKDRALKLW 432 G +D L++W Sbjct: 477 GSRDATLRVW 486 Score = 32.7 bits (73), Expect = 0.86 Identities = 21/66 (31%), Positives = 37/66 (56%), Gaps = 2/66 (3%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISK--QPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNG 186 LVSG+ D T+ +W+ + Q HQ V + F+ + ++ ++S D +VKLW+ Sbjct: 594 LVSGNADSTVKIWDIKTGQCLQTLQGPNKHQSAVTCLQFNKN--FVITSSDDGTVKLWDL 651 Query: 187 ITGKFV 204 TG+F+ Sbjct: 652 KTGEFI 657
>MORG1_XENLA (Q3KQ62) Mitogen-activated protein kinase organizer 1 (MAPK| organizer 1) Length = 314 Score = 74.7 bits (182), Expect = 2e-13 Identities = 36/126 (28%), Positives = 67/126 (53%) Frame = +1 Query: 55 PTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADV 234 P + ++ + ++ +Q V V F+ DG + + DKS+KLWN G + + GH +V Sbjct: 11 PELPQKLQHKLECNQGAVRAVRFNVDGNYCMTCGSDKSLKLWNPHKGSLLKTYSGHGYEV 70 Query: 235 YQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKD 414 + S D+ L S S D T+ +WD+ ++ + GHA +V V ++ + ++SG D Sbjct: 71 LDTAGSCDNSQLCSCSSDKTVILWDVAQGQVVRKFRGHAGKVNCVQFNEEATVIISGSID 130 Query: 415 RALKLW 432 +++ W Sbjct: 131 SSIRCW 136 Score = 62.0 bits (149), Expect = 1e-09 Identities = 40/125 (32%), Positives = 63/125 (50%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 + GSD ++ LW P K +GH V S D L S S DK+V LW+ Sbjct: 41 MTCGSDK-SLKLWNPHKGSLLKT-YSGHGYEVLDTAGSCDNSQLCSCSSDKTVILWDVAQ 98 Query: 193 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVD 372 G+ V FRGH V + ++ ++ +++SGS DS+++ WD R+R+ D + +D Sbjct: 99 GQVVRKFRGHAGKVNCVQFNEEATVIISGSIDSSIRCWDCRSRR--------PDAIQIMD 150 Query: 373 WSPDG 387 + DG Sbjct: 151 EAKDG 155 Score = 45.8 bits (107), Expect = 1e-04 Identities = 47/183 (25%), Positives = 74/183 (40%), Gaps = 42/183 (22%) Frame = +1 Query: 10 RLVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWN-- 183 +L S S D T+ LW+ Q + GH VN V F+ + + S S D S++ W+ Sbjct: 81 QLCSCSSDKTVILWD-VAQGQVVRKFRGHAGKVNCVQFNEEATVIISGSIDSSIRCWDCR 139 Query: 184 ---------------GITGKFVTAF-----------------RGHVADVYQ------ISW 249 GI+ V+A +G + Y +S+ Sbjct: 140 SRRPDAIQIMDEAKDGISSVKVSAHEILAGSVDGNLRRYDLRKGEMCADYLGSPITCVSF 199 Query: 250 SADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVD--WSPDGEKVVSGGKDRAL 423 S DS+ LL+ S DSTL++ D +L + GH + Y +D S V+S +D + Sbjct: 200 SQDSQCLLASSLDSTLRLLDKDTGELLGEYTGHQNLSYKLDSCLSEKDTHVLSCSEDGTV 259 Query: 424 KLW 432 W Sbjct: 260 CFW 262
>PRP46_ASPFU (Q4WT34) Pre-mRNA-splicing factor prp46 (Pre-mRNA-processing| protein 46) Length = 453 Score = 74.7 bits (182), Expect = 2e-13 Identities = 41/138 (29%), Positives = 67/138 (48%) Frame = +1 Query: 19 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 198 SG+ D T+ +W + +TGH V + SP +L S DK VK W+ T K Sbjct: 161 SGAGDRTIKIWNLATGAL-RLTLTGHISTVRGLAVSPRHPYLFSCGEDKMVKCWDLETNK 219 Query: 199 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWS 378 + + GH++ VY ++ LL++G +D +VWD+R R L GH V + Sbjct: 220 VIRHYHGHLSGVYTLALHPRLDLLVTGGRDGVARVWDMRTRSNIHVLSGHKGTVADLKCQ 279 Query: 379 PDGEKVVSGGKDRALKLW 432 ++++G D ++LW Sbjct: 280 EADPQIITGSLDATVRLW 297 Score = 73.2 bits (178), Expect = 6e-13 Identities = 34/116 (29%), Positives = 60/116 (51%) Frame = +1 Query: 85 MTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSR 264 ++GH V + P+ +W AS + D+++K+WN TG GH++ V ++ S Sbjct: 140 ISGHLGWVRSLAVEPNNEWFASGAGDRTIKIWNLATGALRLTLTGHISTVRGLAVSPRHP 199 Query: 265 LLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 L S +D +K WD+ K+ + GH VY + P + +V+GG+D ++W Sbjct: 200 YLFSCGEDKMVKCWDLETNKVIRHYHGHLSGVYTLALHPRLDLLVTGGRDGVARVW 255 Score = 55.1 bits (131), Expect = 2e-07 Identities = 41/152 (26%), Positives = 74/152 (48%), Gaps = 8/152 (5%) Frame = +1 Query: 1 APXRLVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLW 180 A ++++GS D T+ LW+ K +T H+K V ++ P ASAS S+K W Sbjct: 281 ADPQIITGSLDATVRLWDLAAGKTMGV-LTHHKKGVRNLAIHPREFTFASASTG-SIKQW 338 Query: 181 NGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDL-----PG 345 G F+ F GH A + ++ + D+ +L SG + ++ WD + Q + PG Sbjct: 339 KCPEGDFMQNFEGHNAVINSLAVNEDN-VLFSGGDNGSMCFWDWKTGYKFQSIDTMAQPG 397 Query: 346 HADE---VYAVDWSPDGEKVVSGGKDRALKLW 432 D + + + G ++++G D+ +K+W Sbjct: 398 SLDAEAGIMSATFDRTGLRLITGEADKTIKVW 429 Score = 45.1 bits (105), Expect = 2e-04 Identities = 22/79 (27%), Positives = 39/79 (49%) Frame = +1 Query: 196 KFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDW 375 K + GH+ V ++ ++ SG+ D T+K+W++ L+ L GH V + Sbjct: 135 KLMRVISGHLGWVRSLAVEPNNEWFASGAGDRTIKIWNLATGALRLTLTGHISTVRGLAV 194 Query: 376 SPDGEKVVSGGKDRALKLW 432 SP + S G+D+ +K W Sbjct: 195 SPRHPYLFSCGEDKMVKCW 213 Score = 33.9 bits (76), Expect = 0.38 Identities = 30/140 (21%), Positives = 55/140 (39%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 LV+G D +W+ ++GH+ V + + + S D +V+LW+ Sbjct: 243 LVTGGRDGVARVWDMRTRSNIHV-LSGHKGTVADLKCQEADPQIITGSLDATVRLWDLAA 301 Query: 193 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVD 372 GK + H V ++ S S S +K W Q+ GH + ++ Sbjct: 302 GKTMGVLTHHKKGVRNLAIHPREFTFASASTGS-IKQWKCPEGDFMQNFEGHNAVINSLA 360 Query: 373 WSPDGEKVVSGGKDRALKLW 432 + D + SGG + ++ W Sbjct: 361 VNED-NVLFSGGDNGSMCFW 379
>FBXW7_MOUSE (Q8VBV4) F-box/WD-repeat protein 7 (F-box and WD-40 domain protein| 7) (F-box protein FBW7) (F-box protein Fbxw6) (F-box-WD40 repeat protein 6) (SEL-10) Length = 629 Score = 74.7 bits (182), Expect = 2e-13 Identities = 48/141 (34%), Positives = 74/141 (52%) Frame = +1 Query: 10 RLVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGI 189 R+VSGSDD T+ +W K + + GH V + + S S D+++K+WN Sbjct: 315 RIVSGSDDNTLKVWSAVTGKCLRT-LVGHTGGVWSSQMRDN--IIISGSTDRTLKVWNAE 371 Query: 190 TGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAV 369 TG+ + GH + V + + ++SGS+D+TL+VWDI + L GH V V Sbjct: 372 TGECIHTLYGHTSTVRCMH--LHEKRVVSGSRDATLRVWDIETGQCLHVLMGHVAAVRCV 429 Query: 370 DWSPDGEKVVSGGKDRALKLW 432 + DG +VVSG D +K+W Sbjct: 430 QY--DGRRVVSGAYDFMVKVW 448 Score = 67.4 bits (163), Expect = 3e-11 Identities = 42/140 (30%), Positives = 73/140 (52%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 ++SGS D T+ +W + + GH V ++ + + S S D ++++W+ T Sbjct: 356 IISGSTDRTLKVWNAETGECIHT-LYGHTSTVRCMHLHE--KRVVSGSRDATLRVWDIET 412 Query: 193 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVD 372 G+ + GHVA V + + D R ++SG+ D +KVWD L GH + VY++ Sbjct: 413 GQCLHVLMGHVAAVRCVQY--DGRRVVSGAYDFMVKVWDPETETCLHTLQGHTNRVYSLQ 470 Query: 373 WSPDGEKVVSGGKDRALKLW 432 + DG VVSG D ++++W Sbjct: 471 F--DGIHVVSGSLDTSIRVW 488 Score = 65.9 bits (159), Expect = 9e-11 Identities = 43/142 (30%), Positives = 71/142 (50%), Gaps = 1/142 (0%) Frame = +1 Query: 10 RLVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGI 189 R+VSG+ DF + +W+P ++ + GH V + F DG + S S D S+++W+ Sbjct: 435 RVVSGAYDFMVKVWDPE-TETCLHTLQGHTNRVYSLQF--DGIHVVSGSLDTSIRVWDVE 491 Query: 190 TGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAV 369 TG + GH + +L+SG+ DST+K+WDI+ + Q L G + AV Sbjct: 492 TGNCIHTLTGHQS--LTSGMELKDNILVSGNADSTVKIWDIKTGQCLQTLQGPSKHQSAV 549 Query: 370 DWSPDGEK-VVSGGKDRALKLW 432 + V++ D +KLW Sbjct: 550 TCLQFNKNFVITSSDDGTVKLW 571 Score = 65.1 bits (157), Expect = 2e-10 Identities = 41/130 (31%), Positives = 62/130 (47%), Gaps = 2/130 (1%) Frame = +1 Query: 49 WEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVA 228 W K PK V+ + F G + S S D ++K+W+ +TGK + GH Sbjct: 287 WRRGELKSPKVLKGHDDHVITCLQFC--GNRIVSGSDDNTLKVWSAVTGKCLRTLVGHTG 344 Query: 229 DVYQISWSADSR--LLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVS 402 V WS+ R +++SGS D TLKVW+ + L GH V + ++VVS Sbjct: 345 GV----WSSQMRDNIIISGSTDRTLKVWNAETGECIHTLYGHTSTVRCMHLHE--KRVVS 398 Query: 403 GGKDRALKLW 432 G +D L++W Sbjct: 399 GSRDATLRVW 408 Score = 33.1 bits (74), Expect = 0.66 Identities = 21/66 (31%), Positives = 38/66 (57%), Gaps = 2/66 (3%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISK--QPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNG 186 LVSG+ D T+ +W+ + Q + HQ V + F+ + ++ ++S D +VKLW+ Sbjct: 516 LVSGNADSTVKIWDIKTGQCLQTLQGPSKHQSAVTCLQFNKN--FVITSSDDGTVKLWDL 573 Query: 187 ITGKFV 204 TG+F+ Sbjct: 574 KTGEFI 579
>SPG16_MOUSE (Q8K450) Sperm-associated antigen 16 protein (PF20 protein homolog)| Length = 639 Score = 74.7 bits (182), Expect = 2e-13 Identities = 41/142 (28%), Positives = 71/142 (50%), Gaps = 2/142 (1%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTG--HQKVVNHVYFSPDGQWLASASFDKSVKLWNG 186 L+S S+D LW+ Q +TG H ++ F P G LA++S D ++KLW+ Sbjct: 375 LISCSEDR---LWKMVGLPQGNVLLTGSGHTDWLSGCCFHPSGSKLATSSGDSTIKLWDL 431 Query: 187 ITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYA 366 G+ GH V+ +W + + S S D T K+WD+ + + + L GH D V + Sbjct: 432 NKGECTLTLEGHNHAVWSCTWHSCGDFVASASLDMTSKIWDVNSERCRYTLYGHTDSVNS 491 Query: 367 VDWSPDGEKVVSGGKDRALKLW 432 +++ P +++ D+ L +W Sbjct: 492 IEFFPFSNILLTASADKTLSVW 513 Score = 70.1 bits (170), Expect = 5e-12 Identities = 44/141 (31%), Positives = 65/141 (46%) Frame = +1 Query: 10 RLVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGI 189 +L + S D T+ LW+ + + GH V + G ++ASAS D + K+W+ Sbjct: 416 KLATSSGDSTIKLWDLN-KGECTLTLEGHNHAVWSCTWHSCGDFVASASLDMTSKIWDVN 474 Query: 190 TGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAV 369 + + GH V I + S +LL+ S D TL VWD R K +Q L GH V Sbjct: 475 SERCRYTLYGHTDSVNSIEFFPFSNILLTASADKTLSVWDARTGKCEQSLYGHMHSVNDA 534 Query: 370 DWSPDGEKVVSGGKDRALKLW 432 ++P G + S KLW Sbjct: 535 TFTPRGHIIASCDARGVTKLW 555 Score = 62.4 bits (150), Expect = 1e-09 Identities = 47/182 (25%), Positives = 75/182 (41%), Gaps = 41/182 (22%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 + S S D T +W+ S++ + + GH VN + F P L +AS DK++ +W+ T Sbjct: 459 VASASLDMTSKIWDVN-SERCRYTLYGHTDSVNSIEFFPFSNILLTASADKTLSVWDART 517 Query: 193 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIR------------------- 315 GK + GH+ V +++ ++ S K+WD R Sbjct: 518 GKCEQSLYGHMHSVNDATFTPRGHIIASCDARGVTKLWDFRKLIPIVSIDVGPSSGNEVN 577 Query: 316 ----ARKLKQ------------------DLPGHADEVYAVDWSPDGEKVVSGGKDRALKL 429 R L Q L GH EV++V +S GE + SGG D ++L Sbjct: 578 FDQSGRVLAQASANGIIHLLDLKSGQIHKLVGHESEVHSVVFSHLGENLYSGGSDGTIRL 637 Query: 430 WM 435 W+ Sbjct: 638 WI 639 Score = 49.7 bits (117), Expect = 7e-06 Identities = 30/113 (26%), Positives = 48/113 (42%) Frame = +1 Query: 94 HQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLLL 273 H+ V+ + P +L S S D+ K+ G + GH + + L Sbjct: 359 HELPVSCIVMHPCRDYLISCSEDRLWKMVGLPQGNVLLTGSGHTDWLSGCCFHPSGSKLA 418 Query: 274 SGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 + S DST+K+WD+ + L GH V++ W G+ V S D K+W Sbjct: 419 TSSGDSTIKLWDLNKGECTLTLEGHNHAVWSCTWHSCGDFVASASLDMTSKIW 471
>TB1RA_XENLA (Q7SZM9) F-box-like/WD-repeat-containing protein TBL1XR1-A| (Transducin beta-like 1X-related protein 1-A) (Nuclear receptor corepressor/HDAC3 complex subunit TBLR1-A) (TBL1-related protein 1-A) (xTBLR1) Length = 519 Score = 74.7 bits (182), Expect = 2e-13 Identities = 41/130 (31%), Positives = 64/130 (49%), Gaps = 9/130 (6%) Frame = +1 Query: 70 QPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISW 249 +P GH VN + + P G LAS S D ++K+W+ V + H ++Y I W Sbjct: 345 RPIKTFQGHTNEVNAIKWDPTGNLLASCSDDMTLKIWSMKHDTCVHDLQAHNKEIYTIKW 404 Query: 250 SAD---------SRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVS 402 S + +L S S DST+++WD+ L H + VY+V +SPDG + S Sbjct: 405 SPTGPGTNNPNANLMLASASFDSTVRLWDVDRGICIHTLTKHQEPVYSVAFSPDGRYLAS 464 Query: 403 GGKDRALKLW 432 G D+ + +W Sbjct: 465 GSFDKCVHIW 474 Score = 65.9 bits (159), Expect = 9e-11 Identities = 38/101 (37%), Positives = 58/101 (57%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 L S S D T+ LW+ +T HQ+ V V FSPDG++LAS SFDK V +WN T Sbjct: 420 LASASFDSTVRLWDVDRGICIHT-LTKHQEPVYSVAFSPDGRYLASGSFDKCVHIWNTQT 478 Query: 193 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIR 315 G V ++RG ++++ W+A + + + D ++ V D+R Sbjct: 479 GALVHSYRG-TGGIFEVCWNAAGDKVGASASDGSVCVLDLR 518 Score = 64.3 bits (155), Expect = 3e-10 Identities = 43/143 (30%), Positives = 65/143 (45%), Gaps = 9/143 (6%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQ---------WLASASFDK 165 L S SDD T+ +W + H K + + +SP G LASASFD Sbjct: 369 LASCSDDMTLKIWSMKHDTCVHD-LQAHNKEIYTIKWSPTGPGTNNPNANLMLASASFDS 427 Query: 166 SVKLWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPG 345 +V+LW+ G + H VY +++S D R L SGS D + +W+ + L G Sbjct: 428 TVRLWDVDRGICIHTLTKHQEPVYSVAFSPDGRYLASGSFDKCVHIWNTQTGALVHSYRG 487 Query: 346 HADEVYAVDWSPDGEKVVSGGKD 414 ++ V W+ G+KV + D Sbjct: 488 -TGGIFEVCWNAAGDKVGASASD 509 Score = 59.7 bits (143), Expect = 7e-09 Identities = 39/149 (26%), Positives = 62/149 (41%), Gaps = 9/149 (6%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 ++S D T +W+ + K + H V + + + AS S D + + Sbjct: 286 ILSAGVDKTTIIWDAHTG-EAKQQFPFHSAPALDVDWQSNNTF-ASCSTDMCIHVCKLGQ 343 Query: 193 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVD 372 + + F+GH +V I W LL S S D TLK+W ++ DL H E+Y + Sbjct: 344 DRPIKTFQGHTNEVNAIKWDPTGNLLASCSDDMTLKIWSMKHDTCVHDLQAHNKEIYTIK 403 Query: 373 WSPDGE---------KVVSGGKDRALKLW 432 WSP G + S D ++LW Sbjct: 404 WSPTGPGTNNPNANLMLASASFDSTVRLW 432 Score = 57.4 bits (137), Expect = 3e-08 Identities = 36/140 (25%), Positives = 63/140 (45%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 L +GS D +W T + + H+ + + ++ G ++ SA DK+ +W+ T Sbjct: 245 LATGSYDGFARIW--TKDGNLASTLGQHKGPIFALKWNKKGNFILSAGVDKTTIIWDAHT 302 Query: 193 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVD 372 G+ F H A + W +++ S S D + V + + + GH +EV A+ Sbjct: 303 GEAKQQFPFHSAPALDVDWQSNN-TFASCSTDMCIHVCKLGQDRPIKTFQGHTNEVNAIK 361 Query: 373 WSPDGEKVVSGGKDRALKLW 432 W P G + S D LK+W Sbjct: 362 WDPTGNLLASCSDDMTLKIW 381 Score = 52.8 bits (125), Expect = 8e-07 Identities = 32/130 (24%), Positives = 57/130 (43%), Gaps = 14/130 (10%) Frame = +1 Query: 85 MTGHQKVVNHVYFSPDGQWLASASFDKSVKLW----NGITGKFVTAFRGHV--------- 225 + GH+ V ++P LAS S D + ++W N +G R + Sbjct: 170 LRGHESEVFICAWNPVSDLLASGSGDSTARIWNLSENSTSGSTQLVLRHCIREGGQDVPS 229 Query: 226 -ADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVS 402 DV + W+++ LL +GS D ++W + L L H ++A+ W+ G ++S Sbjct: 230 NKDVTSLDWNSEGTLLATGSYDGFARIW-TKDGNLASTLGQHKGPIFALKWNKKGNFILS 288 Query: 403 GGKDRALKLW 432 G D+ +W Sbjct: 289 AGVDKTTIIW 298
>APAF_HUMAN (O14727) Apoptotic protease-activating factor 1 (Apaf-1)| Length = 1248 Score = 74.3 bits (181), Expect = 3e-13 Identities = 40/115 (34%), Positives = 62/115 (53%), Gaps = 2/115 (1%) Frame = +1 Query: 94 HQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSR--L 267 H+ V FS D +++A+ S DK VK+WN +TG+ V + H V ++ S L Sbjct: 656 HEDEVLCCAFSTDDRFIATCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSHHLL 715 Query: 268 LLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 L +GS D LK+WD+ ++ + + GH + V +SPD + + S D LKLW Sbjct: 716 LATGSSDCFLKLWDLNQKECRNTMFGHTNSVNHCRFSPDDKLLASCSADGTLKLW 770 Score = 63.5 bits (153), Expect = 5e-10 Identities = 40/113 (35%), Positives = 57/113 (50%) Frame = +1 Query: 94 HQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLLL 273 H+K V H+ F+ D + L S+S D +++WN K + RGH V +SR LL Sbjct: 1002 HKKTVWHIQFTADEKTLISSSDDAEIQVWNWQLDKCI-FLRGHQETVKDFRLLKNSR-LL 1059 Query: 274 SGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 S S D T+KVW+I ++D H V + D S D K S D+ K+W Sbjct: 1060 SWSFDGTVKVWNIITGNKEKDFVCHQGTVLSCDISHDATKFSSTSADKTAKIW 1112 Score = 60.5 bits (145), Expect = 4e-09 Identities = 48/195 (24%), Positives = 76/195 (38%), Gaps = 55/195 (28%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 L +GS D + LW+ K+ + M GH VNH FSPD + LAS S D ++KLW+ + Sbjct: 716 LATGSSDCFLKLWDLN-QKECRNTMFGHTNSVNHCRFSPDDKLLASCSADGTLKLWDATS 774 Query: 193 G---------KFVTAFRGHVADVYQI----SWSADSRLLLSGSKDS-------------- 291 +F D+ I SWSAD ++ +K+ Sbjct: 775 ANERKSINVKQFFLNLEDPQEDMEVIVKCCSWSADGARIMVAAKNKIFLFDIHTSGLLGE 834 Query: 292 ----------------------------TLKVWDIRARKLKQDLPGHADEVYAVDWSPDG 387 +++W+ +R D GH V+ V +SPDG Sbjct: 835 IHTGHHSTIQYCDFSPQNHLAVVALSQYCVELWNTDSRSKVADCRGHLSWVHGVMFSPDG 894 Query: 388 EKVVSGGKDRALKLW 432 ++ D+ ++LW Sbjct: 895 SSFLTSSDDQTIRLW 909 Score = 58.5 bits (140), Expect = 1e-08 Identities = 43/140 (30%), Positives = 62/140 (44%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 L+S SDD + +W + K R GHQ+ V + + L S SFD +VK+WN IT Sbjct: 1018 LISSSDDAEIQVWNWQLDKCIFLR--GHQETVKDFRLLKNSR-LLSWSFDGTVKVWNIIT 1074 Query: 193 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVD 372 G F H V S D+ S S D T K+W +L GH V Sbjct: 1075 GNKEKDFVCHQGTVLSCDISHDATKFSSTSADKTAKIWSFDLLLPLHELRGHNGCVRCSA 1134 Query: 373 WSPDGEKVVSGGKDRALKLW 432 +S D + +G + +++W Sbjct: 1135 FSVDSTLLATGDDNGEIRIW 1154 Score = 52.4 bits (124), Expect = 1e-06 Identities = 39/141 (27%), Positives = 66/141 (46%), Gaps = 8/141 (5%) Frame = +1 Query: 10 RLVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGI 189 RL+S S D T+ +W I+ + HQ V S D +S S DK+ K+W+ Sbjct: 1057 RLLSWSFDGTVKVWN-IITGNKEKDFVCHQGTVLSCDISHDATKFSSTSADKTAKIWSFD 1115 Query: 190 TGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKL--------KQDLPG 345 + RGH V ++S DS LL +G + +++W++ +L ++ Sbjct: 1116 LLLPLHELRGHNGCVRCSAFSVDSTLLATGDDNGEIRIWNVSNGELLHLCAPLSEEGAAT 1175 Query: 346 HADEVYAVDWSPDGEKVVSGG 408 H V + +SPDG+ ++S G Sbjct: 1176 HGGWVTDLCFSPDGKMLISAG 1196 Score = 48.5 bits (114), Expect = 2e-05 Identities = 23/76 (30%), Positives = 38/76 (50%) Frame = +1 Query: 88 TGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRL 267 TGH + + FSP A V+LWN + V RGH++ V+ + +S D Sbjct: 837 TGHHSTIQYCDFSPQNHLAVVALSQYCVELWNTDSRSKVADCRGHLSWVHGVMFSPDGSS 896 Query: 268 LLSGSKDSTLKVWDIR 315 L+ S D T+++W+ + Sbjct: 897 FLTSSDDQTIRLWETK 912 Score = 39.3 bits (90), Expect = 0.009 Identities = 20/73 (27%), Positives = 34/73 (46%) Frame = +1 Query: 214 RGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEK 393 R H VY +S D + + S D TL+V+ + ++ H DEV +S D Sbjct: 612 RPHTDAVYHACFSEDGQRIASCGADKTLQVFKAETGEKLLEIKAHEDEVLCCAFSTDDRF 671 Query: 394 VVSGGKDRALKLW 432 + + D+ +K+W Sbjct: 672 IATCSVDKKVKIW 684
>WSB2_HUMAN (Q9NYS7) WD repeat and SOCS box-containing protein 2 (WSB-2) (CS| box-containing WD protein) Length = 404 Score = 74.3 bits (181), Expect = 3e-13 Identities = 45/142 (31%), Positives = 75/142 (52%), Gaps = 2/142 (1%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQW-LASASFDKSVKLWN-G 186 L +G +D + +WE ++GHQ VV + F+P G L SAS DK++++W+ Sbjct: 126 LATGLNDGQIKIWEVQTGLL-LLNLSGHQDVVRDLSFTPSGSLILVSASRDKTLRIWDLN 184 Query: 187 ITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYA 366 GK + GH+ VY S S D +L S + + ++ +W +R+ L + L GH V + Sbjct: 185 KHGKQIQVLSGHLQWVYCCSISPDCSMLCSAAGEKSVFLWSMRSYTLIRKLEGHQSSVVS 244 Query: 367 VDWSPDGEKVVSGGKDRALKLW 432 D+SPD +V+ D + +W Sbjct: 245 CDFSPDSALLVTASYDTNVIMW 266 Score = 66.2 bits (160), Expect = 7e-11 Identities = 46/152 (30%), Positives = 73/152 (48%), Gaps = 12/152 (7%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 LVS S D T+ +W+ + ++GH + V SPD L SA+ +KSV LW+ + Sbjct: 169 LVSASRDKTLRIWDLNKHGKQIQVLSGHLQWVYCCSISPDCSMLCSAAGEKSVFLWSMRS 228 Query: 193 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWD----IRARKL--------KQD 336 + GH + V +S DS LL++ S D+ + +WD R R L D Sbjct: 229 YTLIRKLEGHQSSVVSCDFSPDSALLVTASYDTNVIMWDPYTGERLRSLHHTQVDPAMDD 288 Query: 337 LPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 H + +V +SP+G + + DR L++W Sbjct: 289 SDVHISSLRSVCFSPEGLYLATVADDRLLRIW 320 Score = 47.4 bits (111), Expect = 3e-05 Identities = 36/153 (23%), Positives = 68/153 (44%), Gaps = 13/153 (8%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 L S + + ++FLW S ++ GHQ V FSPD L +AS+D +V +W+ T Sbjct: 212 LCSAAGEKSVFLWSMR-SYTLIRKLEGHQSSVVSCDFSPDSALLVTASYDTNVIMWDPYT 270 Query: 193 GKFVTAFRG------------HVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQD 336 G+ + + H++ + + +S + L + + D L++W A +LK Sbjct: 271 GERLRSLHHTQVDPAMDDSDVHISSLRSVCFSPEGLYLATVADDRLLRIW---ALELKTP 327 Query: 337 LP-GHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 + + P G + +G +D ++ W Sbjct: 328 IAFAPMTNGLCCTFFPHGGVIATGTRDGHVQFW 360 Score = 43.1 bits (100), Expect = 6e-04 Identities = 18/57 (31%), Positives = 34/57 (59%), Gaps = 1/57 (1%) Frame = +1 Query: 265 LLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKV-VSGGKDRALKLW 432 +L +G D +K+W+++ L +L GH D V + ++P G + VS +D+ L++W Sbjct: 125 VLATGLNDGQIKIWEVQTGLLLLNLSGHQDVVRDLSFTPSGSLILVSASRDKTLRIW 181
>CAF1B_MOUSE (Q9D0N7) Chromatin assembly factor 1 subunit B (CAF-1 subunit B)| (Chromatin assembly factor I p60 subunit) (CAF-I 60 kDa subunit) (CAF-Ip60) Length = 572 Score = 74.3 bits (181), Expect = 3e-13 Identities = 49/168 (29%), Positives = 69/168 (41%), Gaps = 27/168 (16%) Frame = +1 Query: 10 RLVSGSDDFTMFLWEPTISKQPKA------RMTGHQKVVNHVYFSPDGQWLASASFDKSV 171 RL S D + +W+ KA + H K VN V FSP G+ LAS D + Sbjct: 31 RLASAGVDTAVRIWKLERGPDGKAIVEFLSNLARHTKAVNVVRFSPTGEILASGGDDAVI 90 Query: 172 KLWNGITGK---------------------FVTAFRGHVADVYQISWSADSRLLLSGSKD 288 LW K V RGH+ DVY I W+ D L+ S S D Sbjct: 91 LLWKMNDSKEPEQIAFQDEEEAQLNKENWTVVKTLRGHLEDVYDICWATDGNLMTSASVD 150 Query: 289 STLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 +T+ +WD+ + H V V W P G+ + + DR L+++ Sbjct: 151 NTVIIWDVSKGQKISIFNEHKSYVQGVTWDPLGQYIATLSCDRVLRIY 198 Score = 51.2 bits (121), Expect = 2e-06 Identities = 29/125 (23%), Positives = 59/125 (47%), Gaps = 20/125 (16%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKA--------------------RMTGHQKVVNHVYFSPD 132 L SG DD + LW+ SK+P+ + GH + V + ++ D Sbjct: 81 LASGGDDAVILLWKMNDSKEPEQIAFQDEEEAQLNKENWTVVKTLRGHLEDVYDICWATD 140 Query: 133 GQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDI 312 G + SAS D +V +W+ G+ ++ F H + V ++W + + + S D L++++ Sbjct: 141 GNLMTSASVDNTVIIWDVSKGQKISIFNEHKSYVQGVTWDPLGQYIATLSCDRVLRIYNT 200 Query: 313 RARKL 327 + +++ Sbjct: 201 QKKRV 205
>CAF1_DROME (Q24572) Probable histone-binding protein Caf1 (Chromatin assembly| factor 1 p55 subunit) (CAF-1 p55 subunit) (dCAF-1) (Nucleosome remodeling factor 55 kDa subunit) (NURF-55) Length = 430 Score = 74.3 bits (181), Expect = 3e-13 Identities = 54/155 (34%), Positives = 78/155 (50%), Gaps = 15/155 (9%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKAR--------MTGHQKVVNHVYFSPDGQWL-ASASFDK 165 L+S SDD T+ LW+ I+ PK TGH VV V + + L S + D+ Sbjct: 197 LLSASDDHTICLWD--INATPKEHRVIDAKNIFTGHTAVVEDVAWHLLHESLFGSVADDQ 254 Query: 166 SVKLW---NGITGKFVTAFRGHVADVYQISWSADSRLLLS-GSKDSTLKVWDIRARKLK- 330 + +W N T K H A+V +S++ S +L+ GS D T+ +WD+R KLK Sbjct: 255 KLMIWDTRNNNTSKPSHTVDAHTAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKL 314 Query: 331 QDLPGHADEVYAVDWSPDGEKVV-SGGKDRALKLW 432 H DE++ V WSP E ++ S G DR L +W Sbjct: 315 HSFESHKDEIFQVQWSPHNETILASSGTDRRLHVW 349
>TUP1_KLULA (P56094) Transcriptional repressor TUP1| Length = 682 Score = 74.3 bits (181), Expect = 3e-13 Identities = 46/158 (29%), Positives = 71/158 (44%), Gaps = 49/158 (31%) Frame = +1 Query: 106 VNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSK 285 + V FSPDG++LA+ + DK +++W+ T K V +GH D+Y + + L+SGS Sbjct: 409 IRSVCFSPDGKFLATGAEDKLIRIWDLETKKIVMTLKGHEQDIYSLDYFPSGNKLVSGSG 468 Query: 286 DSTLKVWD----------------------------IRARKLKQDL-------------- 339 D T+++WD I A L + + Sbjct: 469 DRTVRIWDLTTGTCSLTLSIEDGVTTVAVSPGEGKFIAAGSLDRTVRVWDSDTGFLVERL 528 Query: 340 -------PGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 GH D VY+V ++ DG+ VVSG DR++KLW Sbjct: 529 DSENELGTGHRDSVYSVVFTRDGKGVVSGSLDRSVKLW 566 Score = 68.6 bits (166), Expect = 1e-11 Identities = 45/156 (28%), Positives = 80/156 (51%), Gaps = 15/156 (9%) Frame = +1 Query: 10 RLVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSP-DGQWLASASFDKSVKLWNG 186 +LVSGS D T+ +W+ T + + V V SP +G+++A+ S D++V++W+ Sbjct: 462 KLVSGSGDRTVRIWDLTTG--TCSLTLSIEDGVTTVAVSPGEGKFIAAGSLDRTVRVWDS 519 Query: 187 ITGKFVTAF-------RGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRA-------RK 324 TG V GH VY + ++ D + ++SGS D ++K+W++ + Sbjct: 520 DTGFLVERLDSENELGTGHRDSVYSVVFTRDGKGVVSGSLDRSVKLWNLNGLSGQKSHAE 579 Query: 325 LKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 + GH D V +V + + E ++SG KDR + W Sbjct: 580 CEVTYTGHKDFVLSVATTQNDEYILSGSKDRGVLFW 615 Score = 66.2 bits (160), Expect = 7e-11 Identities = 27/83 (32%), Positives = 51/83 (61%), Gaps = 2/83 (2%) Frame = +1 Query: 190 TGKFVTAFRGHVADVY--QISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVY 363 TG +A +D+Y + +S D + L +G++D +++WD+ +K+ L GH ++Y Sbjct: 393 TGNQNSAASTASSDLYIRSVCFSPDGKFLATGAEDKLIRIWDLETKKIVMTLKGHEQDIY 452 Query: 364 AVDWSPDGEKVVSGGKDRALKLW 432 ++D+ P G K+VSG DR +++W Sbjct: 453 SLDYFPSGNKLVSGSGDRTVRIW 475 Score = 61.2 bits (147), Expect = 2e-09 Identities = 45/159 (28%), Positives = 73/159 (45%), Gaps = 19/159 (11%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTIS------KQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVK 174 + +GS D T+ +W+ TGH+ V V F+ DG+ + S S D+SVK Sbjct: 505 IAAGSLDRTVRVWDSDTGFLVERLDSENELGTGHRDSVYSVVFTRDGKGVVSGSLDRSVK 564 Query: 175 LW--NGITGKFVTA-----FRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQ 333 LW NG++G+ A + GH V ++ + + +LSGSKD + WD ++ Sbjct: 565 LWNLNGLSGQKSHAECEVTYTGHKDFVLSVATTQNDEYILSGSKDRGVLFWDTKSGNPLL 624 Query: 334 DLPGHADEVYAV------DWSPDGEKVVSGGKDRALKLW 432 L GH + V +V P+ +G D ++W Sbjct: 625 MLQGHRNSVISVTVANGHPLGPEYGVFATGSGDCKARIW 663
>CAF1B_HUMAN (Q13112) Chromatin assembly factor 1 subunit B (CAF-1 subunit B)| (Chromatin assembly factor I p60 subunit) (CAF-I 60 kDa subunit) (CAF-Ip60) (M-phase phosphoprotein 7) Length = 559 Score = 73.9 bits (180), Expect = 3e-13 Identities = 50/168 (29%), Positives = 68/168 (40%), Gaps = 27/168 (16%) Frame = +1 Query: 10 RLVSGSDDFTMFLWEPTISKQPKA------RMTGHQKVVNHVYFSPDGQWLASASFDKSV 171 RL S D + +W+ KA + H K VN V FSP G+ LAS D + Sbjct: 31 RLASAGVDTNVRIWKVEKGPDGKAIVEFLSNLARHTKAVNVVRFSPTGEILASGGDDAVI 90 Query: 172 KLWNGITGK---------------------FVTAFRGHVADVYQISWSADSRLLLSGSKD 288 LW K V RGH+ DVY I W+ D L+ S S D Sbjct: 91 LLWKVNDNKEPEQIAFQDEDEAQLNKENWTVVKTLRGHLEDVYDICWATDGNLMASASVD 150 Query: 289 STLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 +T +WD+ + H V V W P G+ V + DR L+++ Sbjct: 151 NTAIIWDVSKGQKISIFNEHKSYVQGVTWDPLGQYVATLSCDRVLRVY 198 Score = 51.6 bits (122), Expect = 2e-06 Identities = 30/125 (24%), Positives = 59/125 (47%), Gaps = 20/125 (16%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKA--------------------RMTGHQKVVNHVYFSPD 132 L SG DD + LW+ +K+P+ + GH + V + ++ D Sbjct: 81 LASGGDDAVILLWKVNDNKEPEQIAFQDEDEAQLNKENWTVVKTLRGHLEDVYDICWATD 140 Query: 133 GQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDI 312 G +ASAS D + +W+ G+ ++ F H + V ++W + + + S D L+V+ I Sbjct: 141 GNLMASASVDNTAIIWDVSKGQKISIFNEHKSYVQGVTWDPLGQYVATLSCDRVLRVYSI 200 Query: 313 RARKL 327 + +++ Sbjct: 201 QKKRV 205
>RBBP7_RAT (Q71UF4) Histone-binding protein RBBP7 (Retinoblastoma-binding| protein 7) (RBBP-7) Length = 425 Score = 73.9 bits (180), Expect = 3e-13 Identities = 54/153 (35%), Positives = 78/153 (50%), Gaps = 13/153 (8%) Frame = +1 Query: 13 LVSGSDDFTMFLWE----PTISK--QPKARMTGHQKVVNHVYFSPDGQWL-ASASFDKSV 171 L+S SDD T+ LW+ P K KA TGH VV V + + L S + D+ + Sbjct: 192 LLSASDDHTVCLWDINAGPKEGKIVDAKAIFTGHSAVVEDVAWHLLHESLFGSVADDQKL 251 Query: 172 KLWN---GITGKFVTAFRGHVADVYQISWSADSRLLLS-GSKDSTLKVWDIRARKLK-QD 336 +W+ T K H A+V +S++ S +L+ GS D T+ +WD+R KLK Sbjct: 252 MIWDTRSNTTSKPSHLVDAHTAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKLHT 311 Query: 337 LPGHADEVYAVDWSPDGEKVV-SGGKDRALKLW 432 H DE++ V WSP E ++ S G DR L +W Sbjct: 312 FESHKDEIFQVHWSPHNETILASSGTDRRLNVW 344
>RBBP7_MOUSE (Q60973) Histone-binding protein RBBP7 (Retinoblastoma-binding| protein 7) (RBBP-7) (Retinoblastoma-binding protein p46) (Histone acetyltransferase type B subunit 2) Length = 425 Score = 73.9 bits (180), Expect = 3e-13 Identities = 54/153 (35%), Positives = 78/153 (50%), Gaps = 13/153 (8%) Frame = +1 Query: 13 LVSGSDDFTMFLWE----PTISK--QPKARMTGHQKVVNHVYFSPDGQWL-ASASFDKSV 171 L+S SDD T+ LW+ P K KA TGH VV V + + L S + D+ + Sbjct: 192 LLSASDDHTVCLWDINAGPKEGKIVDAKAIFTGHSAVVEDVAWHLLHESLFGSVADDQKL 251 Query: 172 KLWN---GITGKFVTAFRGHVADVYQISWSADSRLLLS-GSKDSTLKVWDIRARKLK-QD 336 +W+ T K H A+V +S++ S +L+ GS D T+ +WD+R KLK Sbjct: 252 MIWDTRSNTTSKPSHLVDAHTAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKLHT 311 Query: 337 LPGHADEVYAVDWSPDGEKVV-SGGKDRALKLW 432 H DE++ V WSP E ++ S G DR L +W Sbjct: 312 FESHKDEIFQVHWSPHNETILASSGTDRRLNVW 344
>RBBP7_MACFA (Q4R304) Histone-binding protein RBBP7 (Retinoblastoma-binding| protein 7) (RBBP-7) Length = 425 Score = 73.9 bits (180), Expect = 3e-13 Identities = 54/153 (35%), Positives = 78/153 (50%), Gaps = 13/153 (8%) Frame = +1 Query: 13 LVSGSDDFTMFLWE----PTISK--QPKARMTGHQKVVNHVYFSPDGQWL-ASASFDKSV 171 L+S SDD T+ LW+ P K KA TGH VV V + + L S + D+ + Sbjct: 192 LLSASDDHTVCLWDINAGPKEGKIVDAKAIFTGHSAVVEDVAWHLLHESLFGSVADDQKL 251 Query: 172 KLWN---GITGKFVTAFRGHVADVYQISWSADSRLLLS-GSKDSTLKVWDIRARKLK-QD 336 +W+ T K H A+V +S++ S +L+ GS D T+ +WD+R KLK Sbjct: 252 MIWDTRSNTTSKPSHLVDAHTAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKLHT 311 Query: 337 LPGHADEVYAVDWSPDGEKVV-SGGKDRALKLW 432 H DE++ V WSP E ++ S G DR L +W Sbjct: 312 FESHKDEIFQVHWSPHNETILASSGTDRRLNVW 344
>RBBP7_HUMAN (Q16576) Histone-binding protein RBBP7 (Retinoblastoma-binding| protein 7) (RBBP-7) (Retinoblastoma-binding protein p46) (Histone acetyltransferase type B subunit 2) Length = 425 Score = 73.9 bits (180), Expect = 3e-13 Identities = 54/153 (35%), Positives = 78/153 (50%), Gaps = 13/153 (8%) Frame = +1 Query: 13 LVSGSDDFTMFLWE----PTISK--QPKARMTGHQKVVNHVYFSPDGQWL-ASASFDKSV 171 L+S SDD T+ LW+ P K KA TGH VV V + + L S + D+ + Sbjct: 192 LLSASDDHTVCLWDINAGPKEGKIVDAKAIFTGHSAVVEDVAWHLLHESLFGSVADDQKL 251 Query: 172 KLWN---GITGKFVTAFRGHVADVYQISWSADSRLLLS-GSKDSTLKVWDIRARKLK-QD 336 +W+ T K H A+V +S++ S +L+ GS D T+ +WD+R KLK Sbjct: 252 MIWDTRSNTTSKPSHLVDAHTAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKLHT 311 Query: 337 LPGHADEVYAVDWSPDGEKVV-SGGKDRALKLW 432 H DE++ V WSP E ++ S G DR L +W Sbjct: 312 FESHKDEIFQVHWSPHNETILASSGTDRRLNVW 344
>RBBP7_BOVIN (Q3SWX8) Histone-binding protein RBBP7 (Retinoblastoma-binding| protein 7) (RBBP-7) Length = 425 Score = 73.9 bits (180), Expect = 3e-13 Identities = 54/153 (35%), Positives = 78/153 (50%), Gaps = 13/153 (8%) Frame = +1 Query: 13 LVSGSDDFTMFLWE----PTISK--QPKARMTGHQKVVNHVYFSPDGQWL-ASASFDKSV 171 L+S SDD T+ LW+ P K KA TGH VV V + + L S + D+ + Sbjct: 192 LLSASDDHTVCLWDINAGPKEGKIVDAKAIFTGHSAVVEDVAWHLLHESLFGSVADDQKL 251 Query: 172 KLWN---GITGKFVTAFRGHVADVYQISWSADSRLLLS-GSKDSTLKVWDIRARKLK-QD 336 +W+ T K H A+V +S++ S +L+ GS D T+ +WD+R KLK Sbjct: 252 MIWDTRSNTTSKPSHLVDAHTAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKLHT 311 Query: 337 LPGHADEVYAVDWSPDGEKVV-SGGKDRALKLW 432 H DE++ V WSP E ++ S G DR L +W Sbjct: 312 FESHKDEIFQVHWSPHNETILASSGTDRRLNVW 344
>POF1_SCHPO (P87053) F-box/WD-repeat protein pof1 (Skp1-binding protein 1)| Length = 605 Score = 73.9 bits (180), Expect = 3e-13 Identities = 50/146 (34%), Positives = 74/146 (50%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 LVSGS D T+ LW S + + GH VN V D + S S D ++K+W+ T Sbjct: 366 LVSGSADCTVKLWH--FSGGKRITLRGHTGPVNSVRIIRDRGLVLSGSDDSTIKIWSLET 423 Query: 193 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVD 372 + F H+ V ++ ADSRL S S D T+K WDI +K L GH + V+ + Sbjct: 424 NTCLHTFSAHIGPVQSLAL-ADSRLF-SCSLDGTIKQWDIEKKKCVHTLFGHIEGVWEI- 480 Query: 373 WSPDGEKVVSGGKDRALKLWMN*ACL 450 + D +++SG D +K+W C+ Sbjct: 481 -AADHLRLISGAHDGVVKVWEACECV 505 Score = 62.8 bits (151), Expect = 8e-10 Identities = 35/97 (36%), Positives = 53/97 (54%) Frame = +1 Query: 142 LASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRAR 321 LAS S+D +++LWN T + V GH + V + + D L+SGS D T+++W+ R Sbjct: 286 LASGSYDATIRLWNLATFQQVALLEGHSSGVTCLQF--DQCKLISGSMDKTIRIWNYRTS 343 Query: 322 KLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 + L GH D V + + D +VSG D +KLW Sbjct: 344 ECISILHGHTDSVLCLTF--DSTLLVSGSADCTVKLW 378 Score = 60.8 bits (146), Expect = 3e-09 Identities = 45/141 (31%), Positives = 66/141 (46%) Frame = +1 Query: 10 RLVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGI 189 +L+SGS D T+ +W S+ + GH V + F D L S S D +VKLW+ Sbjct: 325 KLISGSMDKTIRIWNYRTSECISI-LHGHTDSVLCLTF--DSTLLVSGSADCTVKLWHFS 381 Query: 190 TGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAV 369 GK +T RGH V + D L+LSGS DST+K+W + H V ++ Sbjct: 382 GGKRIT-LRGHTGPVNSVRIIRDRGLVLSGSDDSTIKIWSLETNTCLHTFSAHIGPVQSL 440 Query: 370 DWSPDGEKVVSGGKDRALKLW 432 + ++ S D +K W Sbjct: 441 ALA--DSRLFSCSLDGTIKQW 459 Score = 37.7 bits (86), Expect = 0.027 Identities = 17/56 (30%), Positives = 34/56 (60%) Frame = +1 Query: 265 LLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 +L SGS D+T+++W++ + L GH+ V + + D K++SG D+ +++W Sbjct: 285 ILASGSYDATIRLWNLATFQQVALLEGHSSGVTCLQF--DQCKLISGSMDKTIRIW 338
>GBB4_RAT (O35353) Guanine nucleotide-binding protein beta subunit 4| (Transducin beta chain 4) Length = 339 Score = 73.9 bits (180), Expect = 3e-13 Identities = 39/116 (33%), Positives = 61/116 (52%) Frame = +1 Query: 85 MTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSR 264 + GH ++ F DGQ + S+ D + LW+ TG+ T F GH DV +S S D + Sbjct: 138 LPGHTGYLSCCRFLDDGQIITSSG-DTTCALWDIETGQQTTTFTGHSGDVMSLSLSPDLK 196 Query: 265 LLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 +SG+ D++ K+WDIR +Q GH ++ AV + P G +G D +L+ Sbjct: 197 TFVSGACDASSKLWDIRDGMCRQSFTGHISDINAVSFFPSGYAFATGSDDATCRLF 252 Score = 61.2 bits (147), Expect = 2e-09 Identities = 40/146 (27%), Positives = 73/146 (50%), Gaps = 5/146 (3%) Frame = +1 Query: 10 RLVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGI 189 ++++ S D T LW+ +Q TGH V + SPD + S + D S KLW+ Sbjct: 155 QIITSSGDTTCALWDIETGQQTTT-FTGHSGDVMSLSLSPDLKTFVSGACDASSKLWDIR 213 Query: 190 TGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADE---- 357 G +F GH++D+ +S+ +GS D+T +++D+RA Q+L ++ + Sbjct: 214 DGMCRQSFTGHISDINAVSFFPSGYAFATGSDDATCRLFDLRA---DQELLLYSHDNIIC 270 Query: 358 -VYAVDWSPDGEKVVSGGKDRALKLW 432 + +V +S G +++G D +W Sbjct: 271 GITSVAFSKSGRLLLAGYDDFNCSVW 296 Score = 53.9 bits (128), Expect = 4e-07 Identities = 25/73 (34%), Positives = 37/73 (50%) Frame = +1 Query: 214 RGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEK 393 RGH+A +Y + W DSRLL+S S+D L +WD +P + V ++P G Sbjct: 51 RGHLAKIYAMHWGYDSRLLVSASQDGKLIIWDSYTTNKMHAIPLRSSWVMTCAYAPSGNY 110 Query: 394 VVSGGKDRALKLW 432 V GG D ++ Sbjct: 111 VACGGLDNICSIY 123 Score = 43.5 bits (101), Expect = 5e-04 Identities = 27/128 (21%), Positives = 58/128 (45%), Gaps = 4/128 (3%) Frame = +1 Query: 61 ISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQ 240 I + + + GH + +++ D + L SAS D + +W+ T + A + V Sbjct: 42 IQMRTRRTLRGHLAKIYAMHWGYDSRLLVSASQDGKLIIWDSYTTNKMHAIPLRSSWVMT 101 Query: 241 ISWSADSRLLLSGSKDSTLKVWDIRAR----KLKQDLPGHADEVYAVDWSPDGEKVVSGG 408 +++ + G D+ +++++ R ++ ++LPGH + + DG+ + S G Sbjct: 102 CAYAPSGNYVACGGLDNICSIYNLKTREGNVRVSRELPGHTGYLSCCRFLDDGQIITSSG 161 Query: 409 KDRALKLW 432 D LW Sbjct: 162 -DTTCALW 168 Score = 38.1 bits (87), Expect = 0.020 Identities = 25/100 (25%), Positives = 46/100 (46%), Gaps = 3/100 (3%) Frame = +1 Query: 19 SGSDDFTMFLWEPTISKQPKARMTGHQKVV---NHVYFSPDGQWLASASFDKSVKLWNGI 189 +GSDD T L++ + + + H ++ V FS G+ L + D + +W+ + Sbjct: 242 TGSDDATCRLFD--LRADQELLLYSHDNIICGITSVAFSKSGRLLLAGYDDFNCSVWDAL 299 Query: 190 TGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWD 309 G GH V + + D + +GS DS L++W+ Sbjct: 300 KGGRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLRIWN 339
>GBB4_MOUSE (P29387) Guanine nucleotide-binding protein beta subunit 4| (Transducin beta chain 4) Length = 339 Score = 73.9 bits (180), Expect = 3e-13 Identities = 39/116 (33%), Positives = 61/116 (52%) Frame = +1 Query: 85 MTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSR 264 + GH ++ F DGQ + S+ D + LW+ TG+ T F GH DV +S S D + Sbjct: 138 LPGHTGYLSCCRFLDDGQIITSSG-DTTCALWDIETGQQTTTFTGHSGDVMSLSLSPDLK 196 Query: 265 LLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 +SG+ D++ K+WDIR +Q GH ++ AV + P G +G D +L+ Sbjct: 197 TFVSGACDASSKLWDIRDGMCRQSFTGHISDINAVSFFPSGYAFATGSDDATCRLF 252 Score = 61.2 bits (147), Expect = 2e-09 Identities = 40/146 (27%), Positives = 73/146 (50%), Gaps = 5/146 (3%) Frame = +1 Query: 10 RLVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGI 189 ++++ S D T LW+ +Q TGH V + SPD + S + D S KLW+ Sbjct: 155 QIITSSGDTTCALWDIETGQQTTT-FTGHSGDVMSLSLSPDLKTFVSGACDASSKLWDIR 213 Query: 190 TGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADE---- 357 G +F GH++D+ +S+ +GS D+T +++D+RA Q+L ++ + Sbjct: 214 DGMCRQSFTGHISDINAVSFFPSGYAFATGSDDATCRLFDLRA---DQELLLYSHDNIIC 270 Query: 358 -VYAVDWSPDGEKVVSGGKDRALKLW 432 + +V +S G +++G D +W Sbjct: 271 GITSVAFSKSGRLLLAGYDDFNCSVW 296 Score = 53.9 bits (128), Expect = 4e-07 Identities = 25/73 (34%), Positives = 37/73 (50%) Frame = +1 Query: 214 RGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEK 393 RGH+A +Y + W DSRLL+S S+D L +WD +P + V ++P G Sbjct: 51 RGHLAKIYAMHWGYDSRLLVSASQDGKLIIWDSYTTNKMHAIPLRSSWVMTCAYAPSGNY 110 Query: 394 VVSGGKDRALKLW 432 V GG D ++ Sbjct: 111 VACGGLDNICSIY 123 Score = 43.5 bits (101), Expect = 5e-04 Identities = 27/128 (21%), Positives = 58/128 (45%), Gaps = 4/128 (3%) Frame = +1 Query: 61 ISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQ 240 I + + + GH + +++ D + L SAS D + +W+ T + A + V Sbjct: 42 IQMRTRRTLRGHLAKIYAMHWGYDSRLLVSASQDGKLIIWDSYTTNKMHAIPLRSSWVMT 101 Query: 241 ISWSADSRLLLSGSKDSTLKVWDIRAR----KLKQDLPGHADEVYAVDWSPDGEKVVSGG 408 +++ + G D+ +++++ R ++ ++LPGH + + DG+ + S G Sbjct: 102 CAYAPSGNYVACGGLDNICSIYNLKTREGNVRVSRELPGHTGYLSCCRFLDDGQIITSSG 161 Query: 409 KDRALKLW 432 D LW Sbjct: 162 -DTTCALW 168 Score = 37.4 bits (85), Expect = 0.035 Identities = 25/100 (25%), Positives = 46/100 (46%), Gaps = 3/100 (3%) Frame = +1 Query: 19 SGSDDFTMFLWEPTISKQPKARMTGHQKVV---NHVYFSPDGQWLASASFDKSVKLWNGI 189 +GSDD T L++ + + + H ++ V FS G+ L + D + +W+ + Sbjct: 242 TGSDDATCRLFD--LRADQELLLYSHDNIICGITSVAFSKSGRLLLAGYDDFNCSVWDAL 299 Query: 190 TGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWD 309 G GH V + + D + +GS DS L++W+ Sbjct: 300 KGGRSGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLRIWN 339
>LIN23_CAEEL (Q09990) F-box/WD-repeat protein lin-23 (Abnormal cell lineage| protein 23) Length = 665 Score = 73.9 bits (180), Expect = 3e-13 Identities = 44/142 (30%), Positives = 81/142 (57%), Gaps = 2/142 (1%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKAR--MTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNG 186 +V+ S D ++ +W+ + R + GH+ VN V F D +++ SAS D+++K+W+ Sbjct: 315 MVTCSKDRSIAVWDMVSPRDITIRRVLVGHRAAVNVVDF--DDRYIVSASGDRTIKVWSM 372 Query: 187 ITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYA 366 T +FV GH + + + RL++SGS D+T+++WDI + + L GH + V Sbjct: 373 DTLEFVRTLAGHRRGIACLQYRG--RLVVSGSSDNTIRLWDIHSGVCLRVLEGHEELVRC 430 Query: 367 VDWSPDGEKVVSGGKDRALKLW 432 + + D +++VSG D +K+W Sbjct: 431 IRF--DEKRIVSGAYDGKIKVW 450 Score = 53.5 bits (127), Expect = 5e-07 Identities = 39/144 (27%), Positives = 75/144 (52%), Gaps = 3/144 (2%) Frame = +1 Query: 10 RLVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGI 189 ++VSG D T+ +W+ + ++GH V + + D + + S S D +V++W+ Sbjct: 234 KIVSGLRDNTIKIWDRKDYSCSRI-LSGHTGSVLCLQY--DNRVIISGSSDATVRVWDVE 290 Query: 190 TGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDI---RARKLKQDLPGHADEV 360 TG+ + H V + ++ + ++++ SKD ++ VWD+ R +++ L GH V Sbjct: 291 TGECIKTLIHHCEAVLHLRFA--NGIMVTCSKDRSIAVWDMVSPRDITIRRVLVGHRAAV 348 Query: 361 YAVDWSPDGEKVVSGGKDRALKLW 432 VD+ D +VS DR +K+W Sbjct: 349 NVVDF--DDRYIVSASGDRTIKVW 370 Score = 47.4 bits (111), Expect = 3e-05 Identities = 26/101 (25%), Positives = 52/101 (51%) Frame = +1 Query: 130 DGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWD 309 D + S D ++K+W+ GH V + + D+R+++SGS D+T++VWD Sbjct: 231 DDDKIVSGLRDNTIKIWDRKDYSCSRILSGHTGSVLCLQY--DNRVIISGSSDATVRVWD 288 Query: 310 IRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 + + + L H + V + ++ +V+ KDR++ +W Sbjct: 289 VETGECIKTLIHHCEAVLHLRFA--NGIMVTCSKDRSIAVW 327
>MORG1_MOUSE (Q9DAJ4) Mitogen-activated protein kinase organizer 1 (MAPK| organizer 1) Length = 315 Score = 73.6 bits (179), Expect = 4e-13 Identities = 38/130 (29%), Positives = 67/130 (51%), Gaps = 3/130 (2%) Frame = +1 Query: 52 EPTISKQPKARMTG---HQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGH 222 +P + P+ RM Q V V F+ DG + + DK++KLWN + G + + GH Sbjct: 7 KPRAPELPQKRMKTLDCSQGAVRAVRFNVDGNYCLTCGSDKTLKLWNPLRGTLLRTYSGH 66 Query: 223 VADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVS 402 +V + S D+ L SG D T+ +WD+ ++ + GHA +V V ++ + ++S Sbjct: 67 GYEVLDAAGSFDNSHLCSGGGDKTVVLWDVATGQVVRKFRGHAGKVNTVQFNEEATVILS 126 Query: 403 GGKDRALKLW 432 G D +++ W Sbjct: 127 GSIDSSVRCW 136 Score = 65.1 bits (157), Expect = 2e-10 Identities = 39/104 (37%), Positives = 56/104 (53%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 L GSD T+ LW P + +GH V S D L S DK+V LW+ T Sbjct: 41 LTCGSDK-TLKLWNPLRGTLLRT-YSGHGYEVLDAAGSFDNSHLCSGGGDKTVVLWDVAT 98 Query: 193 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARK 324 G+ V FRGH V + ++ ++ ++LSGS DS+++ WD R+RK Sbjct: 99 GQVVRKFRGHAGKVNTVQFNEEATVILSGSIDSSVRCWDCRSRK 142 Score = 36.6 bits (83), Expect = 0.059 Identities = 24/89 (26%), Positives = 44/89 (49%), Gaps = 2/89 (2%) Frame = +1 Query: 121 FSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSR--LLLSGSKDST 294 FS DGQ +S D +++L + TG+ + + GH Y++ R ++S S+D Sbjct: 199 FSRDGQCTLISSLDSTLRLLDKDTGELLGEYVGHKNQQYKLDCCLSERDTHVVSCSEDGK 258 Query: 295 LKVWDIRARKLKQDLPGHADEVYAVDWSP 381 + WD+ L LP ++ V ++ + P Sbjct: 259 VFFWDLVEGALALALPVGSNVVQSLAYHP 287
>WDR1_CAEEL (Q11176) Actin-interacting protein 1 (AIP1) (Uncoordinated protein| 78) Length = 611 Score = 73.6 bits (179), Expect = 4e-13 Identities = 39/120 (32%), Positives = 64/120 (53%), Gaps = 7/120 (5%) Frame = +1 Query: 4 PXRLVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWN 183 P R++SGSDD T+ ++E K K+ H K V+ V ++PDG AS D ++ L+N Sbjct: 160 PFRIISGSDDNTVAIFEGPPFKF-KSTFGEHTKFVHSVRYNPDGSLFASTGGDGTIVLYN 218 Query: 184 GITGKFVTAFR-------GHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLP 342 G+ G F H V+ ++WS D + S S D T+K+W++ K+++ +P Sbjct: 219 GVDGTKTGVFEDDSLKNVAHSGSVFGLTWSPDGTKIASASADKTIKIWNVATLKVEKTIP 278 Score = 42.7 bits (99), Expect = 8e-04 Identities = 36/146 (24%), Positives = 65/146 (44%), Gaps = 9/146 (6%) Frame = +1 Query: 22 GSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSV---KLWNGIT 192 G D + +++ + + + + H + V FS +G +L + + V + N Sbjct: 466 GGQDSKVHVYKLSGASVSEVKTIVHPAEITSVAFSNNGAFLVATDQSRKVIPYSVANNFE 525 Query: 193 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLP-----GHA-D 354 ++ H A V +SWS D+ L +GS D+++ VW++ D P HA Sbjct: 526 LAHTNSWTFHTAKVACVSWSPDNVRLATGSLDNSVIVWNMNK---PSDHPIIIKGAHAMS 582 Query: 355 EVYAVDWSPDGEKVVSGGKDRALKLW 432 V +V W + +VS G+D +K W Sbjct: 583 SVNSVIWLNE-TTIVSAGQDSNIKFW 607 Score = 34.3 bits (77), Expect = 0.29 Identities = 36/160 (22%), Positives = 53/160 (33%), Gaps = 55/160 (34%) Frame = +1 Query: 94 HQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT--------------------------- 192 H V + +SPDG +ASAS DK++K+WN T Sbjct: 238 HSGSVFGLTWSPDGTKIASASADKTIKIWNVATLKVEKTIPVGTRIEDQQLGIIWTKQAL 297 Query: 193 ----------------GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARK 324 G GH + +S SAD + L S + + WDI Sbjct: 298 VSISANGFINFVNPELGSIDQVRYGHNKAITALSSSADGKTLFSADAEGHINSWDISTGI 357 Query: 325 LKQDLPG-HA-----------DEVYAVDWSPDGEKVVSGG 408 + P HA +++ V W + V +GG Sbjct: 358 SNRVFPDVHATMITGIKTTSKGDLFTVSWDDHLKVVPAGG 397 Score = 34.3 bits (77), Expect = 0.29 Identities = 35/165 (21%), Positives = 57/165 (34%), Gaps = 50/165 (30%) Frame = +1 Query: 88 TGHQKVVNHVYFSPDGQWLASASFDKSVKLWN-----GITGKFVTAFRGHVADVYQISWS 252 T H SP G + AS +V++W+ I + F G V D ISW Sbjct: 56 TEHSHQTTVAKTSPSGYYCASGDVHGNVRIWDTTQTTHILKTTIPVFSGPVKD---ISWD 112 Query: 253 ADSR---------------------------------------------LLLSGSKDSTL 297 ++S+ ++SGS D+T+ Sbjct: 113 SESKRIAAVGEGRERFGHVFLFDTGTSNGNLTGQARAMNSVDFKPSRPFRIISGSDDNTV 172 Query: 298 KVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 +++ K K H V++V ++PDG S G D + L+ Sbjct: 173 AIFEGPPFKFKSTFGEHTKFVHSVRYNPDGSLFASTGGDGTIVLY 217
>PRL2_ARATH (Q39190) PP1/PP2A phosphatases pleiotropic regulator PRL2| Length = 479 Score = 73.6 bits (179), Expect = 4e-13 Identities = 33/116 (28%), Positives = 56/116 (48%) Frame = +1 Query: 85 MTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSR 264 + GH V V F P +W + S D+++K+W+ TG GH+ V ++ S Sbjct: 166 LQGHLGWVRSVAFDPSNEWFCTGSADRTIKIWDVATGVLKLTLTGHIGQVRGLAVSNRHT 225 Query: 265 LLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 + S D +K WD+ K+ + GH VY + P + V++GG+D ++W Sbjct: 226 YMFSAGDDKQVKCWDLEQNKVIRSYHGHLHGVYCLALHPTLDVVLTGGRDSVCRVW 281 Score = 72.8 bits (177), Expect = 7e-13 Identities = 43/138 (31%), Positives = 71/138 (51%) Frame = +1 Query: 19 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 198 +GS D T+ +W+ K +TGH V + S ++ SA DK VK W+ K Sbjct: 187 TGSADRTIKIWDVATGVL-KLTLTGHIGQVRGLAVSNRHTYMFSAGDDKQVKCWDLEQNK 245 Query: 199 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWS 378 + ++ GH+ VY ++ ++L+G +DS +VWDIR + LP H +V++V Sbjct: 246 VIRSYHGHLHGVYCLALHPTLDVVLTGGRDSVCRVWDIRTKMQIFVLP-HDSDVFSVLAR 304 Query: 379 PDGEKVVSGGKDRALKLW 432 P +V++G D +K W Sbjct: 305 PTDPQVITGSHDSTIKFW 322 Score = 41.6 bits (96), Expect = 0.002 Identities = 36/151 (23%), Positives = 66/151 (43%), Gaps = 10/151 (6%) Frame = +1 Query: 10 RLVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGI 189 ++++GS D T+ W+ K A +T H+K V + P SAS D ++K ++ Sbjct: 309 QVITGSHDSTIKFWDLRYGKS-MATITNHKKTVRAMALHPKENDFVSASAD-NIKKFSLP 366 Query: 190 TGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDI-------RARKLKQDLPGH 348 G+F D+ + ++++G L WD RA + Q PG Sbjct: 367 KGEFCHNMLSLQRDIINAVAVNEDGVMVTGGDKGGLWFWDWKSGHNFQRAETIVQ--PGS 424 Query: 349 ADE---VYAVDWSPDGEKVVSGGKDRALKLW 432 + +YA + G ++V+ D+ +K+W Sbjct: 425 LESEAGIYAACYDQTGSRLVTCEGDKTIKMW 455
>PRP46_CANGA (Q6FJZ9) Pre-mRNA-splicing factor PRP46 (Pre-mRNA-processing| protein 46) Length = 427 Score = 73.2 bits (178), Expect = 6e-13 Identities = 40/138 (28%), Positives = 68/138 (49%) Frame = +1 Query: 19 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 198 +GS+D T+ +W K K + H V + S ++ S S DK+VK W+ Sbjct: 133 TGSNDKTIKIWNLASGKL-KVTLKAHDMTVRDLAISNRHPYMFSVSEDKTVKCWDLEKNT 191 Query: 199 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWS 378 + + GH++ V+ + ++++ +DS +KVWDIR R LPGH + V Sbjct: 192 AIRNYHGHLSGVHTVDIHPTVDVVVTAGRDSVVKVWDIRTRLPVMTLPGHKGPITKVRCL 251 Query: 379 PDGEKVVSGGKDRALKLW 432 P +V+S D +++LW Sbjct: 252 PVDPQVISSSVDASIRLW 269 Score = 71.6 bits (174), Expect = 2e-12 Identities = 33/101 (32%), Positives = 54/101 (53%) Frame = +1 Query: 130 DGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWD 309 D +W A+ S DK++K+WN +GK + H V ++ S + S S+D T+K WD Sbjct: 127 DNEWFATGSNDKTIKIWNLASGKLKVTLKAHDMTVRDLAISNRHPYMFSVSEDKTVKCWD 186 Query: 310 IRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 + ++ GH V+ VD P + VV+ G+D +K+W Sbjct: 187 LEKNTAIRNYHGHLSGVHTVDIHPTVDVVVTAGRDSVVKVW 227 Score = 40.4 bits (93), Expect = 0.004 Identities = 32/124 (25%), Positives = 55/124 (44%), Gaps = 1/124 (0%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKAR-MTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGI 189 + S S+D T+ W+ + K R GH V+ V P + +A D VK+W+ Sbjct: 173 MFSVSEDKTVKCWD--LEKNTAIRNYHGHLSGVHTVDIHPTVDVVVTAGRDSVVKVWDIR 230 Query: 190 TGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAV 369 T V GH + ++ ++S S D+++++WD+ A K + L H V + Sbjct: 231 TRLPVMTLPGHKGPITKVRCLPVDPQVISSSVDASIRLWDLVAGKSMKVLTHHQRTVRDI 290 Query: 370 DWSP 381 P Sbjct: 291 SVHP 294
>WDR12_HUMAN (Q9GZL7) WD-repeat protein 12 (YTM1 homolog)| Length = 423 Score = 73.2 bits (178), Expect = 6e-13 Identities = 52/142 (36%), Positives = 80/142 (56%), Gaps = 5/142 (3%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 + S S D T+ +W+ S K+ +TG+ KV N + +SP + LAS S D+ ++LW+ T Sbjct: 271 ICSASWDHTIRVWDVE-SGSLKSTLTGN-KVFNCISYSPLCKRLASGSTDRHIRLWDPRT 328 Query: 193 --GKFVT-AFRGHVADVYQISWS-ADSRLLLSGSKDSTLKVWDIRARKLK-QDLPGHADE 357 G V+ + H V + WS + L+SGS D+ +K+WD R+ K DL H D+ Sbjct: 329 KDGSLVSLSLTSHTGWVTSVKWSPTHEQQLISGSLDNIVKLWDTRSCKAPLYDLAAHEDK 388 Query: 358 VYAVDWSPDGEKVVSGGKDRAL 423 V +VDW+ G ++SGG D L Sbjct: 389 VLSVDWTDTG-LLLSGGADNKL 409 Score = 66.6 bits (161), Expect = 5e-11 Identities = 46/170 (27%), Positives = 77/170 (45%), Gaps = 30/170 (17%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARM---TGHQKVVNHVYFSPDGQWLASASFDKSVKLWN 183 L+S S D T+ LWE + + + GH V+ + G S S+DK +K+W+ Sbjct: 158 LLSASMDQTILLWEWNVERNKVKALHCCRGHAGSVDSIAVDGSGTKFCSGSWDKMLKIWS 217 Query: 184 --------------------------GITGKFVTAFRGHVADVYQISWSADSRLLLSGSK 285 G+T + GH+ V + WS D+ + S S Sbjct: 218 TVPTDEEDEMEESTNRPRKKQKTEQLGLTRTPIVTLSGHMEAVSSVLWS-DAEEICSASW 276 Query: 286 DSTLKVWDIRARKLKQDLPGHADEVY-AVDWSPDGEKVVSGGKDRALKLW 432 D T++VWD+ + LK L G ++V+ + +SP +++ SG DR ++LW Sbjct: 277 DHTIRVWDVESGSLKSTLTG--NKVFNCISYSPLCKRLASGSTDRHIRLW 324 Score = 66.2 bits (160), Expect = 7e-11 Identities = 41/134 (30%), Positives = 74/134 (55%), Gaps = 5/134 (3%) Frame = +1 Query: 61 ISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQ 240 +++ P ++GH + V+ V +S D + + SAS+D ++++W+ +G + G+ V+ Sbjct: 245 LTRTPIVTLSGHMEAVSSVLWS-DAEEICSASWDHTIRVWDVESGSLKSTLTGN--KVFN 301 Query: 241 -ISWSADSRLLLSGSKDSTLKVWDIRARK---LKQDLPGHADEVYAVDWSPDGEK-VVSG 405 IS+S + L SGS D +++WD R + + L H V +V WSP E+ ++SG Sbjct: 302 CISYSPLCKRLASGSTDRHIRLWDPRTKDGSLVSLSLTSHTGWVTSVKWSPTHEQQLISG 361 Query: 406 GKDRALKLWMN*AC 447 D +KLW +C Sbjct: 362 SLDNIVKLWDTRSC 375 Score = 58.2 bits (139), Expect = 2e-08 Identities = 34/106 (32%), Positives = 56/106 (52%), Gaps = 7/106 (6%) Frame = +1 Query: 136 QWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISW---SADSRLLLSGSKDSTLKVW 306 +W+ + S+DK+ ++W+ + GK + GH V ++W + S LLLS S D T+ +W Sbjct: 112 EWILTGSYDKTSRIWS-LEGKSIMTIVGHTDVVKDVAWVKKDSLSCLLLSASMDQTILLW 170 Query: 307 D--IRARKLK--QDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 + + K+K GHA V ++ G K SG D+ LK+W Sbjct: 171 EWNVERNKVKALHCCRGHAGSVDSIAVDGSGTKFCSGSWDKMLKIW 216 Score = 44.3 bits (103), Expect = 3e-04 Identities = 36/100 (36%), Positives = 47/100 (47%), Gaps = 4/100 (4%) Frame = +1 Query: 10 RLVSGSDDFTMFLWEPTI--SKQPKARMTGHQKVVNHVYFSP-DGQWLASASFDKSVKLW 180 RL SGS D + LW+P +T H V V +SP Q L S S D VKLW Sbjct: 311 RLASGSTDRHIRLWDPRTKDGSLVSLSLTSHTGWVTSVKWSPTHEQQLISGSLDNIVKLW 370 Query: 181 NGITGKF-VTAFRGHVADVYQISWSADSRLLLSGSKDSTL 297 + + K + H V + W+ D+ LLLSG D+ L Sbjct: 371 DTRSCKAPLYDLAAHEDKVLSVDWT-DTGLLLSGGADNKL 409
>RBBP7_BRARE (Q7ZTY4) Histone-binding protein RBBP7 (Retinoblastoma-binding| protein 7) (RBBP-7) Length = 426 Score = 73.2 bits (178), Expect = 6e-13 Identities = 54/155 (34%), Positives = 79/155 (50%), Gaps = 15/155 (9%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKAR--------MTGHQKVVNHVYFSPDGQWL-ASASFDK 165 L+S SDD T+ LW+ IS PK TGH VV V + + L S + D+ Sbjct: 193 LLSASDDHTICLWD--ISGAPKEGKIVDAKTIFTGHTAVVEDVSWHLLHESLFGSVADDQ 250 Query: 166 SVKLWN---GITGKFVTAFRGHVADVYQISWSADSRLLLS-GSKDSTLKVWDIRARKLK- 330 + +W+ T K + H A+V +S++ S +L+ GS D T+ +WD+R KLK Sbjct: 251 KLMIWDTRSNNTSKPSHSVDAHTAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKL 310 Query: 331 QDLPGHADEVYAVDWSPDGEKVV-SGGKDRALKLW 432 H DE++ V WSP E ++ S G DR L +W Sbjct: 311 HSFESHKDEIFQVQWSPHNETILASSGTDRRLNVW 345
>RBP4B_XENLA (Q6INH0) Histone-binding protein RBBP4-B (Retinoblastoma-binding| protein 4-B) (RBBP-4-B) (Retinoblastoma-binding protein p48-B) Length = 424 Score = 73.2 bits (178), Expect = 6e-13 Identities = 54/155 (34%), Positives = 79/155 (50%), Gaps = 15/155 (9%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKAR--------MTGHQKVVNHVYFSPDGQWL-ASASFDK 165 L+S SDD T+ LW+ IS PK TGH VV V + + L S + D+ Sbjct: 192 LLSASDDHTICLWD--ISAVPKEGKVVDAKTIFTGHTAVVEDVSWHLLHESLFGSVADDQ 249 Query: 166 SVKLWN---GITGKFVTAFRGHVADVYQISWSADSRLLLS-GSKDSTLKVWDIRARKLK- 330 + +W+ T K + H A+V +S++ S +L+ GS D T+ +WD+R KLK Sbjct: 250 KLMIWDTRSNNTSKPSHSVDAHTAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKL 309 Query: 331 QDLPGHADEVYAVDWSPDGEKVV-SGGKDRALKLW 432 H DE++ V WSP E ++ S G DR L +W Sbjct: 310 HSFESHKDEIFQVQWSPHNETILASSGTDRRLNVW 344
>RBP4A_XENLA (O93377) Histone-binding protein RBBP4-A (Retinoblastoma-binding| protein 4-A) (RBBP-4-A) (Retinoblastoma-binding protein p48-A) Length = 424 Score = 73.2 bits (178), Expect = 6e-13 Identities = 54/155 (34%), Positives = 79/155 (50%), Gaps = 15/155 (9%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKAR--------MTGHQKVVNHVYFSPDGQWL-ASASFDK 165 L+S SDD T+ LW+ IS PK TGH VV V + + L S + D+ Sbjct: 192 LLSASDDHTICLWD--ISAVPKEGKVVDAKTIFTGHTAVVEDVSWHLLHESLFGSVADDQ 249 Query: 166 SVKLWN---GITGKFVTAFRGHVADVYQISWSADSRLLLS-GSKDSTLKVWDIRARKLK- 330 + +W+ T K + H A+V +S++ S +L+ GS D T+ +WD+R KLK Sbjct: 250 KLMIWDTRSNNTSKPSHSVDAHTAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKL 309 Query: 331 QDLPGHADEVYAVDWSPDGEKVV-SGGKDRALKLW 432 H DE++ V WSP E ++ S G DR L +W Sbjct: 310 HSFESHKDEIFQVQWSPHNETILASSGTDRRLNVW 344
>RBBP4_XENTR (Q5M7K4) Histone-binding protein RBBP4 (Retinoblastoma-binding| protein 4) (RBBP-4) Length = 424 Score = 73.2 bits (178), Expect = 6e-13 Identities = 54/155 (34%), Positives = 79/155 (50%), Gaps = 15/155 (9%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKAR--------MTGHQKVVNHVYFSPDGQWL-ASASFDK 165 L+S SDD T+ LW+ IS PK TGH VV V + + L S + D+ Sbjct: 192 LLSASDDHTICLWD--ISAVPKEGKVVDAKTIFTGHTAVVEDVSWHLLHESLFGSVADDQ 249 Query: 166 SVKLWN---GITGKFVTAFRGHVADVYQISWSADSRLLLS-GSKDSTLKVWDIRARKLK- 330 + +W+ T K + H A+V +S++ S +L+ GS D T+ +WD+R KLK Sbjct: 250 KLMIWDTRSNNTSKPSHSVDAHTAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKL 309 Query: 331 QDLPGHADEVYAVDWSPDGEKVV-SGGKDRALKLW 432 H DE++ V WSP E ++ S G DR L +W Sbjct: 310 HSFESHKDEIFQVQWSPHNETILASSGTDRRLNVW 344
>RBBP4_PONPY (Q5RF92) Histone-binding protein RBBP4 (Retinoblastoma-binding| protein 4) (RBBP-4) Length = 424 Score = 73.2 bits (178), Expect = 6e-13 Identities = 54/155 (34%), Positives = 79/155 (50%), Gaps = 15/155 (9%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKAR--------MTGHQKVVNHVYFSPDGQWL-ASASFDK 165 L+S SDD T+ LW+ IS PK TGH VV V + + L S + D+ Sbjct: 192 LLSASDDHTICLWD--ISAVPKEGKVVDAKTIFTGHTAVVEDVSWHLLHESLFGSVADDQ 249 Query: 166 SVKLWN---GITGKFVTAFRGHVADVYQISWSADSRLLLS-GSKDSTLKVWDIRARKLK- 330 + +W+ T K + H A+V +S++ S +L+ GS D T+ +WD+R KLK Sbjct: 250 KLMIWDTRSNNTSKPSHSVDAHTAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKL 309 Query: 331 QDLPGHADEVYAVDWSPDGEKVV-SGGKDRALKLW 432 H DE++ V WSP E ++ S G DR L +W Sbjct: 310 HSFESHKDEIFQVQWSPHNETILASSGTDRRLNVW 344
>RBBP4_MOUSE (Q60972) Histone-binding protein RBBP4 (Retinoblastoma-binding| protein 4) (RBBP-4) (Retinoblastoma-binding protein p48) (Chromatin assembly factor 1 subunit C) (CAF-1 subunit C) (Chromatin assembly factor I p48 subunit) (CAF-I 48 kDa subunit) Length = 424 Score = 73.2 bits (178), Expect = 6e-13 Identities = 54/155 (34%), Positives = 79/155 (50%), Gaps = 15/155 (9%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKAR--------MTGHQKVVNHVYFSPDGQWL-ASASFDK 165 L+S SDD T+ LW+ IS PK TGH VV V + + L S + D+ Sbjct: 192 LLSASDDHTICLWD--ISAVPKKGKVVDAKTIFTGHTAVVEDVSWHLLHESLFGSVADDQ 249 Query: 166 SVKLWN---GITGKFVTAFRGHVADVYQISWSADSRLLLS-GSKDSTLKVWDIRARKLK- 330 + +W+ T K + H A+V +S++ S +L+ GS D T+ +WD+R KLK Sbjct: 250 KLMIWDTRSNNTSKPSHSVDAHTAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKL 309 Query: 331 QDLPGHADEVYAVDWSPDGEKVV-SGGKDRALKLW 432 H DE++ V WSP E ++ S G DR L +W Sbjct: 310 HSFESHKDEIFQVQWSPHNETILASSGTDRRLNVW 344
>RBBP4_HUMAN (Q09028) Histone-binding protein RBBP4 (Retinoblastoma-binding| protein 4) (RBBP-4) (Retinoblastoma-binding protein p48) (Chromatin assembly factor 1 subunit C) (CAF-1 subunit C) (Chromatin assembly factor I p48 subunit) (CAF-I 48 kDa subunit) Length = 424 Score = 73.2 bits (178), Expect = 6e-13 Identities = 54/155 (34%), Positives = 79/155 (50%), Gaps = 15/155 (9%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKAR--------MTGHQKVVNHVYFSPDGQWL-ASASFDK 165 L+S SDD T+ LW+ IS PK TGH VV V + + L S + D+ Sbjct: 192 LLSASDDHTICLWD--ISAVPKEGKVVDAKTIFTGHTAVVEDVSWHLLHESLFGSVADDQ 249 Query: 166 SVKLWN---GITGKFVTAFRGHVADVYQISWSADSRLLLS-GSKDSTLKVWDIRARKLK- 330 + +W+ T K + H A+V +S++ S +L+ GS D T+ +WD+R KLK Sbjct: 250 KLMIWDTRSNNTSKPSHSVDAHTAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKL 309 Query: 331 QDLPGHADEVYAVDWSPDGEKVV-SGGKDRALKLW 432 H DE++ V WSP E ++ S G DR L +W Sbjct: 310 HSFESHKDEIFQVQWSPHNETILASSGTDRRLNVW 344
>RBBP4_CHICK (Q9W7I5) Histone-binding protein RBBP4 (Retinoblastoma-binding| protein 4) (RBBP-4) (Retinoblastoma-binding protein p48) (Chromatin assembly factor 1 subunit C) (CAF-1 subunit C) (Chromatin assembly factor I p48 subunit) (CAF-I 48 kDa subunit) Length = 424 Score = 73.2 bits (178), Expect = 6e-13 Identities = 54/155 (34%), Positives = 79/155 (50%), Gaps = 15/155 (9%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKAR--------MTGHQKVVNHVYFSPDGQWL-ASASFDK 165 L+S SDD T+ LW+ IS PK TGH VV V + + L S + D+ Sbjct: 192 LLSASDDHTICLWD--ISAVPKEGKVVDAKTIFTGHTAVVEDVSWHLLHESLFGSVADDQ 249 Query: 166 SVKLWN---GITGKFVTAFRGHVADVYQISWSADSRLLLS-GSKDSTLKVWDIRARKLK- 330 + +W+ T K + H A+V +S++ S +L+ GS D T+ +WD+R KLK Sbjct: 250 KLMIWDTRSNNTSKPSHSVDAHTAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKL 309 Query: 331 QDLPGHADEVYAVDWSPDGEKVV-SGGKDRALKLW 432 H DE++ V WSP E ++ S G DR L +W Sbjct: 310 HSFESHKDEIFQVQWSPHNETILASSGTDRRLNVW 344
>RBBP4_BOVIN (Q3MHL3) Histone-binding protein RBBP4 (Retinoblastoma-binding| protein 4) (RBBP-4) Length = 424 Score = 73.2 bits (178), Expect = 6e-13 Identities = 54/155 (34%), Positives = 79/155 (50%), Gaps = 15/155 (9%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKAR--------MTGHQKVVNHVYFSPDGQWL-ASASFDK 165 L+S SDD T+ LW+ IS PK TGH VV V + + L S + D+ Sbjct: 192 LLSASDDHTICLWD--ISAVPKEGKVVDAKTIFTGHTAVVEDVSWHLLHESLFGSVADDQ 249 Query: 166 SVKLWN---GITGKFVTAFRGHVADVYQISWSADSRLLLS-GSKDSTLKVWDIRARKLK- 330 + +W+ T K + H A+V +S++ S +L+ GS D T+ +WD+R KLK Sbjct: 250 KLMIWDTRSNNTSKPSHSVDAHTAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKL 309 Query: 331 QDLPGHADEVYAVDWSPDGEKVV-SGGKDRALKLW 432 H DE++ V WSP E ++ S G DR L +W Sbjct: 310 HSFESHKDEIFQVQWSPHNETILASSGTDRRLNVW 344
>A16L1_MOUSE (Q8C0J2) Autophagy-related protein 16-1 (APG16-like 1)| Length = 607 Score = 73.2 bits (178), Expect = 6e-13 Identities = 39/115 (33%), Positives = 58/115 (50%), Gaps = 2/115 (1%) Frame = +1 Query: 94 HQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK--FVTAFRGHVADVYQISWSADSRL 267 H VN V FSP + LA+ D+ VKLW K F + G A + I + + Sbjct: 321 HDGEVNAVQFSPGSRLLATGGMDRRVKLWEAFGDKCEFKGSLSGSNAGITSIEFDSAGAY 380 Query: 268 LLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 LL+ S D ++W + +L+ L GH+ +V + + D ++VSG DR LKLW Sbjct: 381 LLAASNDFASRIWTVDDYRLRHTLTGHSGKVLSAKFLLDNARIVSGSHDRTLKLW 435 Score = 53.5 bits (127), Expect = 5e-07 Identities = 37/143 (25%), Positives = 69/143 (48%), Gaps = 3/143 (2%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISK-QPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGI 189 L +G D + LWE K + K ++G + + F G +L +AS D + ++W Sbjct: 337 LATGGMDRRVKLWEAFGDKCEFKGSLSGSNAGITSIEFDSAGAYLLAASNDFASRIWTVD 396 Query: 190 TGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARK-LKQDLPGHA-DEVY 363 + GH V + D+ ++SGS D TLK+WD+R++ +K G + +++ Sbjct: 397 DYRLRHTLTGHSGKVLSAKFLLDNARIVSGSHDRTLKLWDLRSKVCIKTVFAGSSCNDIV 456 Query: 364 AVDWSPDGEKVVSGGKDRALKLW 432 + + V+SG D+ ++ W Sbjct: 457 CTE-----QCVMSGHFDKKIRFW 474 Score = 51.6 bits (122), Expect = 2e-06 Identities = 43/145 (29%), Positives = 67/145 (46%), Gaps = 4/145 (2%) Frame = +1 Query: 10 RLVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGI 189 R+VSGS D T+ LW+ K G N + + Q + S FDK ++ W+ I Sbjct: 422 RIVSGSHDRTLKLWDLRSKVCIKTVFAGSS--CNDIVCTE--QCVMSGHFDKKIRFWD-I 476 Query: 190 TGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQ--DLPGH--ADE 357 + V + + + + + LLS S+D LKV D+R +KQ PG + Sbjct: 477 RSESVVREMELLGKITALDLNPERTELLSCSRDDLLKVIDLRTNAVKQTFSAPGFKCGSD 536 Query: 358 VYAVDWSPDGEKVVSGGKDRALKLW 432 V +SPDG V +G + +L +W Sbjct: 537 WTRVVFSPDGSYVAAGSAEGSLYVW 561 Score = 40.4 bits (93), Expect = 0.004 Identities = 19/65 (29%), Positives = 36/65 (55%), Gaps = 1/65 (1%) Frame = +1 Query: 115 VYFSPDGQWLASASFDKSVKLWNGITGKFVTAF-RGHVADVYQISWSADSRLLLSGSKDS 291 V FSPDG ++A+ S + S+ +W+ +TGK + H + + ++W+ ++S K S Sbjct: 540 VVFSPDGSYVAAGSAEGSLYVWSVLTGKVEKVLSKQHSSSINAVAWAPSGLHVVSVDKGS 599 Query: 292 TLKVW 306 +W Sbjct: 600 RAVLW 604
>PRP46_KLULA (Q6CKE8) Pre-mRNA-splicing factor PRP46 (Pre-mRNA-processing| protein 46) Length = 434 Score = 73.2 bits (178), Expect = 6e-13 Identities = 39/138 (28%), Positives = 69/138 (50%) Frame = +1 Query: 19 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 198 +GS+D T+ +W+ K K + GH V + S ++ SAS DK VK W+ Sbjct: 140 TGSNDTTIKIWDLAAGKL-KITLIGHVMSVRDIAISKRHPYMFSASEDKLVKCWDLERNT 198 Query: 199 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWS 378 + F GH++ V+ + ++ + +D+ +++WDIR+R LPGH + V Sbjct: 199 AIRDFHGHLSGVHTVDVHPSLDIIATAGRDAVVRLWDIRSRSEIMVLPGHKSPINKVKCL 258 Query: 379 PDGEKVVSGGKDRALKLW 432 P +++S D ++LW Sbjct: 259 PVDPQIISCSGDATVRLW 276 Score = 72.4 bits (176), Expect = 1e-12 Identities = 37/117 (31%), Positives = 57/117 (48%), Gaps = 1/117 (0%) Frame = +1 Query: 85 MTGHQKVVNHVYFSP-DGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADS 261 + GH V V P D +W A+ S D ++K+W+ GK GHV V I+ S Sbjct: 118 INGHTGWVRCVCVDPVDNEWFATGSNDTTIKIWDLAAGKLKITLIGHVMSVRDIAISKRH 177 Query: 262 RLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 + S S+D +K WD+ +D GH V+ VD P + + + G+D ++LW Sbjct: 178 PYMFSASEDKLVKCWDLERNTAIRDFHGHLSGVHTVDVHPSLDIIATAGRDAVVRLW 234 Score = 31.2 bits (69), Expect = 2.5 Identities = 19/78 (24%), Positives = 35/78 (44%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 + + D + LW+ S+ + GH+ +N V P + S S D +V+LW+ I Sbjct: 222 IATAGRDAVVRLWDIR-SRSEIMVLPGHKSPINKVKCLPVDPQIISCSGDATVRLWDIIA 280 Query: 193 GKFVTAFRGHVADVYQIS 246 GK H ++ ++ Sbjct: 281 GKASKVLTHHSRNIRDLT 298
>APAF_MOUSE (O88879) Apoptotic protease-activating factor 1 (Apaf-1)| Length = 1249 Score = 73.2 bits (178), Expect = 6e-13 Identities = 40/115 (34%), Positives = 61/115 (53%), Gaps = 2/115 (1%) Frame = +1 Query: 94 HQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVY--QISWSADSRL 267 H+ V FS D ++A+ S DK VK+W+ TGK V + H V + S++ L Sbjct: 656 HEDEVLCCAFSSDDSYIATCSADKKVKIWDSATGKLVHTYDEHSEQVNCCHFTNSSNHLL 715 Query: 268 LLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 L +GS D LK+WD+ ++ + + GH + V +SPD E + S D L+LW Sbjct: 716 LATGSNDFFLKLWDLNQKECRNTMFGHTNSVNHCRFSPDDELLASCSADGTLRLW 770 Score = 72.8 bits (177), Expect = 7e-13 Identities = 41/114 (35%), Positives = 61/114 (53%) Frame = +1 Query: 91 GHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLL 270 GH+K V H+ F+ DG+ L S+S D +++WN TG +V + H V DSR L Sbjct: 1001 GHKKAVRHIQFTADGKTLISSSEDSVIQVWNWQTGDYV-FLQAHQETVKDFRLLQDSR-L 1058 Query: 271 LSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 LS S D T+KVW++ ++++D H V + S D K S D+ K+W Sbjct: 1059 LSWSFDGTVKVWNVITGRIERDFTCHQGTVLSCAISSDATKFSSTSADKTAKIW 1112 Score = 64.3 bits (155), Expect = 3e-10 Identities = 50/195 (25%), Positives = 80/195 (41%), Gaps = 55/195 (28%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 L +GS+DF + LW+ K+ + M GH VNH FSPD + LAS S D +++LW+ + Sbjct: 716 LATGSNDFFLKLWDLN-QKECRNTMFGHTNSVNHCRFSPDDELLASCSADGTLRLWDVRS 774 Query: 193 G---------KFVTAFRGHVADVYQI----SWSADSRLLLSGSKDSTL------------ 297 +F + DV I SWSAD ++ +K+ L Sbjct: 775 ANERKSINVKRFFLSSEDPPEDVEVIVKCCSWSADGDKIIVAAKNKVLLFDIHTSGLLAE 834 Query: 298 ------------------------------KVWDIRARKLKQDLPGHADEVYAVDWSPDG 387 ++W+I +R D GH V+ V +SPDG Sbjct: 835 IHTGHHSTIQYCDFSPYDHLAVIALSQYCVELWNIDSRLKVADCRGHLSWVHGVMFSPDG 894 Query: 388 EKVVSGGKDRALKLW 432 ++ D+ +++W Sbjct: 895 SSFLTASDDQTIRVW 909 Score = 61.2 bits (147), Expect = 2e-09 Identities = 41/140 (29%), Positives = 63/140 (45%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 L+S S+D + +W + HQ+ V D + L S SFD +VK+WN IT Sbjct: 1018 LISSSEDSVIQVWNWQTGDY--VFLQAHQETVKDFRLLQDSR-LLSWSFDGTVKVWNVIT 1074 Query: 193 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVD 372 G+ F H V + S+D+ S S D T K+W +L GH V Sbjct: 1075 GRIERDFTCHQGTVLSCAISSDATKFSSTSADKTAKIWSFDLLSPLHELKGHNGCVRCSA 1134 Query: 373 WSPDGEKVVSGGKDRALKLW 432 +S DG + +G + +++W Sbjct: 1135 FSLDGILLATGDDNGEIRIW 1154 Score = 46.6 bits (109), Expect = 6e-05 Identities = 24/76 (31%), Positives = 38/76 (50%) Frame = +1 Query: 88 TGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRL 267 TGH + + FSP A V+LWN + V RGH++ V+ + +S D Sbjct: 837 TGHHSTIQYCDFSPYDHLAVIALSQYCVELWNIDSRLKVADCRGHLSWVHGVMFSPDGSS 896 Query: 268 LLSGSKDSTLKVWDIR 315 L+ S D T++VW+ + Sbjct: 897 FLTASDDQTIRVWETK 912 Score = 38.1 bits (87), Expect = 0.020 Identities = 32/160 (20%), Positives = 62/160 (38%), Gaps = 37/160 (23%) Frame = +1 Query: 64 SKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLW--------------------- 180 S+ A GH V+ V FSPDG +AS D+++++W Sbjct: 871 SRLKVADCRGHLSWVHGVMFSPDGSSFLTASDDQTIRVWETKKVCKNSAIVLKQEIDVVF 930 Query: 181 ----------NGITG-KFVTAFRGHV-----ADVYQISWSADSRLLLSGSKDSTLKVWDI 312 + I G + + G + A V S + G +D +K+ ++ Sbjct: 931 QENETMVLAVDNIRGLQLIAGKTGQIDYLPEAQVSCCCLSPHLEYVAFGDEDGAIKIIEL 990 Query: 313 RARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 ++ GH V + ++ DG+ ++S +D +++W Sbjct: 991 PNNRVFSSGVGHKKAVRHIQFTADGKTLISSSEDSVIQVW 1030 Score = 34.7 bits (78), Expect = 0.23 Identities = 33/131 (25%), Positives = 53/131 (40%), Gaps = 9/131 (6%) Frame = +1 Query: 19 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 198 S S D T +W + P + GH V FS DG LA+ + +++WN G+ Sbjct: 1102 STSADKTAKIWSFDLLS-PLHELKGHNGCVRCSAFSLDGILLATGDDNGEIRIWNVSDGQ 1160 Query: 199 F------VTAFRG---HVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHA 351 ++ G H V + +S DS+ L+S LK W++ Q + Sbjct: 1161 LLHSCAPISVEEGTATHGGWVTDVCFSPDSKTLVSAG--GYLKWWNVATGDSSQTFYTNG 1218 Query: 352 DEVYAVDWSPD 384 + + SPD Sbjct: 1219 TNLKKIHVSPD 1229
>MORG1_RAT (Q5BLX8) Mitogen-activated protein kinase organizer 1 (MAPK| organizer 1) Length = 315 Score = 72.8 bits (177), Expect = 7e-13 Identities = 35/126 (27%), Positives = 65/126 (51%) Frame = +1 Query: 55 PTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADV 234 P + ++ + Q V V F+ DG + + DK++KLWN + G + + GH +V Sbjct: 11 PELPRKQLKTLDCGQGAVRAVRFNVDGNYCLTCGSDKTLKLWNPLRGTLLRTYSGHGYEV 70 Query: 235 YQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKD 414 + S D+ L SG D T+ +WD+ ++ + GHA +V V ++ + ++SG D Sbjct: 71 LDAAGSFDNSHLCSGGGDKTVVLWDVATGQVVRKFRGHAGKVNTVQFNEEATVILSGSID 130 Query: 415 RALKLW 432 +++ W Sbjct: 131 SSVRCW 136 Score = 65.1 bits (157), Expect = 2e-10 Identities = 39/104 (37%), Positives = 56/104 (53%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 L GSD T+ LW P + +GH V S D L S DK+V LW+ T Sbjct: 41 LTCGSDK-TLKLWNPLRGTLLRT-YSGHGYEVLDAAGSFDNSHLCSGGGDKTVVLWDVAT 98 Query: 193 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARK 324 G+ V FRGH V + ++ ++ ++LSGS DS+++ WD R+RK Sbjct: 99 GQVVRKFRGHAGKVNTVQFNEEATVILSGSIDSSVRCWDCRSRK 142 Score = 37.0 bits (84), Expect = 0.045 Identities = 24/89 (26%), Positives = 44/89 (49%), Gaps = 2/89 (2%) Frame = +1 Query: 121 FSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSR--LLLSGSKDST 294 FS DGQ +S D +++L + TG+ + + GH Y++ R ++S S+D Sbjct: 199 FSRDGQCTLISSLDSTLRLLDKDTGELLGEYVGHKNQKYKLDCCLSERDTHVVSCSEDGK 258 Query: 295 LKVWDIRARKLKQDLPGHADEVYAVDWSP 381 + WD+ L LP ++ V ++ + P Sbjct: 259 VFFWDLVEGSLALALPVGSNVVQSLAYHP 287
>WDR12_MOUSE (Q9JJA4) WD-repeat protein 12 (YTM1 homolog)| Length = 423 Score = 72.4 bits (176), Expect = 1e-12 Identities = 52/142 (36%), Positives = 80/142 (56%), Gaps = 5/142 (3%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 + S S D T+ +W+ S K+ +TG+ KV N + +SP + LAS S D+ ++LW+ T Sbjct: 271 ICSASWDHTIRVWDVE-SGGLKSTLTGN-KVFNCISYSPLCKRLASGSTDRHIRLWDPRT 328 Query: 193 --GKFVT-AFRGHVADVYQISWS-ADSRLLLSGSKDSTLKVWDIRARKLK-QDLPGHADE 357 G V+ + H V + WS + L+SGS D+ +K+WD R+ K DL H D+ Sbjct: 329 KDGSLVSLSLTSHTGWVTSVKWSPTHEQQLISGSLDNIVKLWDTRSCKAPLYDLAAHEDK 388 Query: 358 VYAVDWSPDGEKVVSGGKDRAL 423 V +VDW+ G ++SGG D L Sbjct: 389 VLSVDWTDTG-LLLSGGADNKL 409 Score = 65.1 bits (157), Expect = 2e-10 Identities = 40/134 (29%), Positives = 74/134 (55%), Gaps = 5/134 (3%) Frame = +1 Query: 61 ISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQ 240 +++ P ++GH + ++ V +S D + + SAS+D ++++W+ +G + G+ V+ Sbjct: 245 LTRTPLVTLSGHTEAISSVLWS-DAEEICSASWDHTIRVWDVESGGLKSTLTGN--KVFN 301 Query: 241 -ISWSADSRLLLSGSKDSTLKVWDIRARK---LKQDLPGHADEVYAVDWSPDGEK-VVSG 405 IS+S + L SGS D +++WD R + + L H V +V WSP E+ ++SG Sbjct: 302 CISYSPLCKRLASGSTDRHIRLWDPRTKDGSLVSLSLTSHTGWVTSVKWSPTHEQQLISG 361 Query: 406 GKDRALKLWMN*AC 447 D +KLW +C Sbjct: 362 SLDNIVKLWDTRSC 375 Score = 64.3 bits (155), Expect = 3e-10 Identities = 45/170 (26%), Positives = 76/170 (44%), Gaps = 30/170 (17%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARM---TGHQKVVNHVYFSPDGQWLASASFDKSVKLWN 183 L++ S D T+ LWE + K + GH V+ + G S S+DK +K+W+ Sbjct: 158 LLTASMDQTVLLWEWNVEKNKVKALHCCRGHAGSVDAIAVDSSGAKFCSGSWDKMLKIWS 217 Query: 184 --------------------------GITGKFVTAFRGHVADVYQISWSADSRLLLSGSK 285 G+T + GH + + WS D+ + S S Sbjct: 218 TVPTDEEDEMEEATNRPRKKQKTEQLGLTRTPLVTLSGHTEAISSVLWS-DAEEICSASW 276 Query: 286 DSTLKVWDIRARKLKQDLPGHADEVY-AVDWSPDGEKVVSGGKDRALKLW 432 D T++VWD+ + LK L G ++V+ + +SP +++ SG DR ++LW Sbjct: 277 DHTIRVWDVESGGLKSTLTG--NKVFNCISYSPLCKRLASGSTDRHIRLW 324 Score = 60.1 bits (144), Expect = 5e-09 Identities = 35/106 (33%), Positives = 54/106 (50%), Gaps = 7/106 (6%) Frame = +1 Query: 136 QWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISW---SADSRLLLSGSKDSTLKVW 306 +W+ S S+DK+ ++W+ + GK + GH V ++W + S LLL+ S D T+ +W Sbjct: 112 EWILSGSYDKTSRIWS-LEGKSIMTIVGHTDVVKDVAWVKKDSLSCLLLTASMDQTVLLW 170 Query: 307 DIRARKLKQDL----PGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 + K K GHA V A+ G K SG D+ LK+W Sbjct: 171 EWNVEKNKVKALHCCRGHAGSVDAIAVDSSGAKFCSGSWDKMLKIW 216 Score = 44.3 bits (103), Expect = 3e-04 Identities = 36/100 (36%), Positives = 47/100 (47%), Gaps = 4/100 (4%) Frame = +1 Query: 10 RLVSGSDDFTMFLWEPTI--SKQPKARMTGHQKVVNHVYFSP-DGQWLASASFDKSVKLW 180 RL SGS D + LW+P +T H V V +SP Q L S S D VKLW Sbjct: 311 RLASGSTDRHIRLWDPRTKDGSLVSLSLTSHTGWVTSVKWSPTHEQQLISGSLDNIVKLW 370 Query: 181 NGITGKF-VTAFRGHVADVYQISWSADSRLLLSGSKDSTL 297 + + K + H V + W+ D+ LLLSG D+ L Sbjct: 371 DTRSCKAPLYDLAAHEDKVLSVDWT-DTGLLLSGGADNKL 409
>TIPD_DICDI (O15736) Protein tipD| Length = 612 Score = 72.4 bits (176), Expect = 1e-12 Identities = 38/131 (29%), Positives = 68/131 (51%) Frame = +1 Query: 40 MFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRG 219 +F E + + K R TGH + + F+ G LA+ DK VK+W+ I+G+ + G Sbjct: 305 VFSSEAMLPSKAKKRWTGHNSEIYCMAFNSIGNLLATGGGDKCVKVWDVISGQQKSTLLG 364 Query: 220 HVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVV 399 + +S+S + +L S D++ ++W+ + + L GH +VY + + +VV Sbjct: 365 ASQSIVSVSFSPNDESILGTSNDNSARLWNTELGRSRHTLTGHIGKVYTGKFI-NSNRVV 423 Query: 400 SGGKDRALKLW 432 +G DR +KLW Sbjct: 424 TGSHDRTIKLW 434 Score = 60.8 bits (146), Expect = 3e-09 Identities = 38/140 (27%), Positives = 68/140 (48%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 L +G D + +W+ IS Q K+ + G + + V FSP+ + + S D S +LWN Sbjct: 339 LATGGGDKCVKVWD-VISGQQKSTLLGASQSIVSVSFSPNDESILGTSNDNSARLWNTEL 397 Query: 193 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVD 372 G+ GH+ VY + +R++ +GS D T+K+WD++ + + + V Sbjct: 398 GRSRHTLTGHIGKVYTGKFINSNRVV-TGSHDRTIKLWDLQKGYCTRTIFCFSSCNDLVI 456 Query: 373 WSPDGEKVVSGGKDRALKLW 432 G + SG D +++ W Sbjct: 457 LGGSGTHLASGHVDHSVRFW 476 Score = 51.6 bits (122), Expect = 2e-06 Identities = 44/148 (29%), Positives = 65/148 (43%), Gaps = 7/148 (4%) Frame = +1 Query: 10 RLVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNH-VYFSPDGQWLASASFDKSVKLWNG 186 R+V+GS D T+ LW+ + K R N V G LAS D SV+ W+ Sbjct: 421 RVVTGSHDRTIKLWD--LQKGYCTRTIFCFSSCNDLVILGGSGTHLASGHVDHSVRFWDS 478 Query: 187 ITGKFVTAFRG-HVADVYQISWS-ADSRLLLSGSKDSTLKVWDIRA----RKLKQDLPGH 348 G+ H + I+ S ++ +L+ S+D TLK+ DIR R K + Sbjct: 479 NAGEPTQVLSSIHEGQITSITNSPTNTNQILTNSRDHTLKIIDIRTFDTIRTFKDPEYRN 538 Query: 349 ADEVYAVDWSPDGEKVVSGGKDRALKLW 432 WSPDG + SG D ++ +W Sbjct: 539 GLNWTKASWSPDGRYIASGSIDGSICIW 566 Score = 46.2 bits (108), Expect = 7e-05 Identities = 23/66 (34%), Positives = 37/66 (56%), Gaps = 3/66 (4%) Frame = +1 Query: 121 FSPDGQWLASASFDKSVKLW---NGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDS 291 +SPDG+++AS S D S+ +W NG T K +T + + V SWS + + +S KD Sbjct: 547 WSPDGRYIASGSIDGSICIWDATNGKTVKVLTKVHNNGSSVCCCSWSPLANIFISADKDK 606 Query: 292 TLKVWD 309 + W+ Sbjct: 607 NIIQWE 612 Score = 45.1 bits (105), Expect = 2e-04 Identities = 33/148 (22%), Positives = 64/148 (43%), Gaps = 8/148 (5%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDG-QWLASASFDKSVKLWNGI 189 L SG D ++ W+ + + + H+ + + SP + + S D ++K+ + Sbjct: 464 LASGHVDHSVRFWDSNAGEPTQVLSSIHEGQITSITNSPTNTNQILTNSRDHTLKIIDIR 523 Query: 190 TGKFVTAFRG----HVADVYQISWSADSRLLLSGSKDSTLKVWDI---RARKLKQDLPGH 348 T + F+ + + + SWS D R + SGS D ++ +WD + K+ + + Sbjct: 524 TFDTIRTFKDPEYRNGLNWTKASWSPDGRYIASGSIDGSICIWDATNGKTVKVLTKVHNN 583 Query: 349 ADEVYAVDWSPDGEKVVSGGKDRALKLW 432 V WSP +S KD+ + W Sbjct: 584 GSSVCCCSWSPLANIFISADKDKNIIQW 611
>A16L1_HUMAN (Q676U5) Autophagy-related protein 16-1 (APG16-like 1)| Length = 607 Score = 72.4 bits (176), Expect = 1e-12 Identities = 39/115 (33%), Positives = 59/115 (51%), Gaps = 2/115 (1%) Frame = +1 Query: 94 HQKVVNHVYFSPDGQWLASASFDKSVKLWN--GITGKFVTAFRGHVADVYQISWSADSRL 267 H VN V FSP + LA+ D+ VKLW G +F + G A + I + + Sbjct: 321 HDGEVNAVQFSPGSRLLATGGMDRRVKLWEVFGEKCEFKGSLSGSNAGITSIEFDSAGSY 380 Query: 268 LLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 LL+ S D ++W + +L+ L GH+ +V + + D ++VSG DR LKLW Sbjct: 381 LLAASNDFASRIWTVDDYRLRHTLTGHSGKVLSAKFLLDNARIVSGSHDRTLKLW 435 Score = 53.5 bits (127), Expect = 5e-07 Identities = 37/143 (25%), Positives = 69/143 (48%), Gaps = 3/143 (2%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISK-QPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGI 189 L +G D + LWE K + K ++G + + F G +L +AS D + ++W Sbjct: 337 LATGGMDRRVKLWEVFGEKCEFKGSLSGSNAGITSIEFDSAGSYLLAASNDFASRIWTVD 396 Query: 190 TGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARK-LKQDLPGHA-DEVY 363 + GH V + D+ ++SGS D TLK+WD+R++ +K G + +++ Sbjct: 397 DYRLRHTLTGHSGKVLSAKFLLDNARIVSGSHDRTLKLWDLRSKVCIKTVFAGSSCNDIV 456 Query: 364 AVDWSPDGEKVVSGGKDRALKLW 432 + + V+SG D+ ++ W Sbjct: 457 CTE-----QCVMSGHFDKKIRFW 474 Score = 52.0 bits (123), Expect = 1e-06 Identities = 42/145 (28%), Positives = 67/145 (46%), Gaps = 4/145 (2%) Frame = +1 Query: 10 RLVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGI 189 R+VSGS D T+ LW+ K G N + + Q + S FDK ++ W+ I Sbjct: 422 RIVSGSHDRTLKLWDLRSKVCIKTVFAGSS--CNDIVCTE--QCVMSGHFDKKIRFWD-I 476 Query: 190 TGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQ--DLPGH--ADE 357 + + + + + + + LLS S+D LKV D+R +KQ PG + Sbjct: 477 RSESIVREMELLGKITALDLNPERTELLSCSRDDLLKVIDLRTNAIKQTFSAPGFKCGSD 536 Query: 358 VYAVDWSPDGEKVVSGGKDRALKLW 432 V +SPDG V +G + +L +W Sbjct: 537 WTRVVFSPDGSYVAAGSAEGSLYIW 561 Score = 40.4 bits (93), Expect = 0.004 Identities = 19/65 (29%), Positives = 35/65 (53%), Gaps = 1/65 (1%) Frame = +1 Query: 115 VYFSPDGQWLASASFDKSVKLWNGITGKFVTAF-RGHVADVYQISWSADSRLLLSGSKDS 291 V FSPDG ++A+ S + S+ +W+ +TGK + H + + ++WS ++S K Sbjct: 540 VVFSPDGSYVAAGSAEGSLYIWSVLTGKVEKVLSKQHSSSINAVAWSPSGSHVVSVDKGC 599 Query: 292 TLKVW 306 +W Sbjct: 600 KAVLW 604 Score = 30.4 bits (67), Expect = 4.2 Identities = 14/56 (25%), Positives = 24/56 (42%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLW 180 + +GS + ++++W K K H +N V +SP G + S LW Sbjct: 549 VAAGSAEGSLYIWSVLTGKVEKVLSKQHSSSINAVAWSPSGSHVVSVDKGCKAVLW 604
>WDR1_DROME (Q9VU68) Putative actin-interacting protein 1 (AIP1)| Length = 608 Score = 72.4 bits (176), Expect = 1e-12 Identities = 41/110 (37%), Positives = 63/110 (57%), Gaps = 2/110 (1%) Frame = +1 Query: 4 PXRLVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWN 183 P R+V+GS+D T+ ++E K K H + V V +SPDG++ ASA FD V L++ Sbjct: 165 PFRIVTGSEDNTIAVFEGPPFKF-KMTKQDHSRFVQAVRYSPDGKFFASAGFDGKVFLYD 223 Query: 184 GITGKFVTAF--RGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKL 327 G + + V F H VY ++W DS LL+ S D T ++W + +R+L Sbjct: 224 GTSSELVGEFGSPAHKGGVYALAWKPDSTQLLTCSGDKTCRLWTVESREL 273 Score = 50.1 bits (118), Expect = 5e-06 Identities = 29/119 (24%), Positives = 56/119 (47%), Gaps = 3/119 (2%) Frame = +1 Query: 85 MTGHQKVVNHVYFSPDGQW-LASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADS 261 ++G K +N F P + + + S D ++ ++ G KF + H V + +S D Sbjct: 148 ISGQSKSINSADFRPARPFRIVTGSEDNTIAVFEGPPFKFKMTKQDHSRFVQAVRYSPDG 207 Query: 262 RLLLSGSKDSTLKVWDIRARKLKQDL--PGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 + S D + ++D + +L + P H VYA+ W PD ++++ D+ +LW Sbjct: 208 KFFASAGFDGKVFLYDGTSSELVGEFGSPAHKGGVYALAWKPDSTQLLTCSGDKTCRLW 266 Score = 45.8 bits (107), Expect = 1e-04 Identities = 36/126 (28%), Positives = 62/126 (49%), Gaps = 5/126 (3%) Frame = +1 Query: 70 QPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFV--TAFRGHVADVYQI 243 +PK + H V V +SPD ++L + + V L++ K + H A V + Sbjct: 481 EPKVELD-HLGAVTDVSYSPDLKYLVACDAHRKVVLYSVEEYKPAHNKEWGFHSARVNTV 539 Query: 244 SWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHA---DEVYAVDWSPDGEKVVSGGKD 414 +WS +S L+ SGS D+T+ +W + A K + +A ++ + W D V+S G+D Sbjct: 540 AWSPNSLLVASGSLDTTIIIWSV-ANPAKHTIIKNAHPQSQITRLVWL-DNNTVISTGQD 597 Query: 415 RALKLW 432 K+W Sbjct: 598 CNTKVW 603 Score = 41.6 bits (96), Expect = 0.002 Identities = 35/162 (21%), Positives = 62/162 (38%), Gaps = 47/162 (29%) Frame = +1 Query: 88 TGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFV--TAFRGHVADVYQISWSADS 261 T H VN +SP G ++AS +++W+ + + + F+ + ISWS D+ Sbjct: 61 TEHSCAVNVAKYSPSGFYIASGDASGKIRIWDTVNKEHLLKNEFQPIAGPIKDISWSPDN 120 Query: 262 R---------------------------------------------LLLSGSKDSTLKVW 306 + +++GS+D+T+ V+ Sbjct: 121 QRIVAVGEGRERFGHVFMSETGTSVGEISGQSKSINSADFRPARPFRIVTGSEDNTIAVF 180 Query: 307 DIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 + K K H+ V AV +SPDG+ S G D + L+ Sbjct: 181 EGPPFKFKMTKQDHSRFVQAVRYSPDGKFFASAGFDGKVFLY 222
>GRWD1_RAT (Q5XI13) Glutamate-rich WD repeat-containing protein 1| Length = 445 Score = 72.4 bits (176), Expect = 1e-12 Identities = 52/158 (32%), Positives = 73/158 (46%), Gaps = 15/158 (9%) Frame = +1 Query: 4 PXRLVSGSDDFTMFLWEPT------ISKQPKARMTGHQKVVNHVYFSP-DGQWLASASFD 162 P RL++G + LW PT + ++P GH + V + +SP + AS S D Sbjct: 226 PGRLLTGDCQKNIHLWTPTDGGSWNVDQRP---FVGHTRSVEDLQWSPTEDTVFASCSAD 282 Query: 163 KSVKLWN--GITGK--FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLK 330 S+++W+ GK +T H DV ISWS LLSG D TLKVWD+R K Sbjct: 283 ASIRIWDIRAAPGKACMLTTAAAHDGDVNVISWSRREPFLLSGGDDGTLKVWDLRQFKSG 342 Query: 331 QDL---PGHADEVYAVDWSP-DGEKVVSGGKDRALKLW 432 + H V +V+W P D + G D + W Sbjct: 343 SPVATFKQHVAPVTSVEWHPQDSGVFAASGADNQITQW 380 Score = 32.3 bits (72), Expect = 1.1 Identities = 26/131 (19%), Positives = 45/131 (34%), Gaps = 52/131 (39%) Frame = +1 Query: 196 KFVTAFRGHVADVYQISWS----------------------------------------- 252 K + +F GH+ + + + WS Sbjct: 204 KPIFSFAGHMGEGFALDWSPRVPGRLLTGDCQKNIHLWTPTDGGSWNVDQRPFVGHTRSV 263 Query: 253 -------ADSRLLLSGSKDSTLKVWDIRARKLKQDL----PGHADEVYAVDWSPDGEKVV 399 + + S S D+++++WDIRA K + H +V + WS ++ Sbjct: 264 EDLQWSPTEDTVFASCSADASIRIWDIRAAPGKACMLTTAAAHDGDVNVISWSRREPFLL 323 Query: 400 SGGKDRALKLW 432 SGG D LK+W Sbjct: 324 SGGDDGTLKVW 334
>WDR12_RAT (P61480) WD-repeat protein 12| Length = 423 Score = 72.0 bits (175), Expect = 1e-12 Identities = 52/140 (37%), Positives = 79/140 (56%), Gaps = 5/140 (3%) Frame = +1 Query: 19 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT-- 192 S S D T+ +W+ S K+ +TG+ KV N + +SP + LAS S D+ ++LW+ T Sbjct: 273 SASWDHTVRVWDVE-SGGLKSTLTGN-KVFNCISYSPLCKRLASGSTDRHIRLWDPRTKD 330 Query: 193 GKFVT-AFRGHVADVYQISWS-ADSRLLLSGSKDSTLKVWDIRARKLK-QDLPGHADEVY 363 G V+ + H V + WS + L+SGS D+ +K+WD R+ K DL H D+V Sbjct: 331 GSLVSLSLTSHTGWVTSVKWSPTHDQQLISGSLDNMVKLWDTRSCKAPLYDLAAHEDKVL 390 Query: 364 AVDWSPDGEKVVSGGKDRAL 423 +VDW+ G ++SGG D L Sbjct: 391 SVDWTDTG-LLLSGGADNKL 409 Score = 63.5 bits (153), Expect = 5e-10 Identities = 40/134 (29%), Positives = 73/134 (54%), Gaps = 5/134 (3%) Frame = +1 Query: 61 ISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQ 240 +++ P ++GH + ++ V +S D + SAS+D +V++W+ +G + G+ V+ Sbjct: 245 LTRTPLVTLSGHTEAISSVLWS-DADEVCSASWDHTVRVWDVESGGLKSTLTGN--KVFN 301 Query: 241 -ISWSADSRLLLSGSKDSTLKVWDIRARK---LKQDLPGHADEVYAVDWSPD-GEKVVSG 405 IS+S + L SGS D +++WD R + + L H V +V WSP ++++SG Sbjct: 302 CISYSPLCKRLASGSTDRHIRLWDPRTKDGSLVSLSLTSHTGWVTSVKWSPTHDQQLISG 361 Query: 406 GKDRALKLWMN*AC 447 D +KLW +C Sbjct: 362 SLDNMVKLWDTRSC 375 Score = 62.0 bits (149), Expect = 1e-09 Identities = 45/170 (26%), Positives = 76/170 (44%), Gaps = 30/170 (17%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARM---TGHQKVVNHVYFSPDGQWLASASFDKSVKLWN 183 L++ S D T+ LWE I + + GH V+ + G S S+DK +K+W+ Sbjct: 158 LLTASMDQTILLWEWNIERNKVKALHCCRGHAGSVDAIAVDSSGTKFCSGSWDKMLKIWS 217 Query: 184 --------------------------GITGKFVTAFRGHVADVYQISWSADSRLLLSGSK 285 G+T + GH + + WS D+ + S S Sbjct: 218 TVPTDEEDEIQEPTNRPRKKQKTEQLGLTRTPLVTLSGHTEAISSVLWS-DADEVCSASW 276 Query: 286 DSTLKVWDIRARKLKQDLPGHADEVY-AVDWSPDGEKVVSGGKDRALKLW 432 D T++VWD+ + LK L G ++V+ + +SP +++ SG DR ++LW Sbjct: 277 DHTVRVWDVESGGLKSTLTG--NKVFNCISYSPLCKRLASGSTDRHIRLW 324 Score = 60.1 bits (144), Expect = 5e-09 Identities = 36/106 (33%), Positives = 56/106 (52%), Gaps = 7/106 (6%) Frame = +1 Query: 136 QWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISW---SADSRLLLSGSKDSTLKVW 306 +W+ S S+DK+ ++W+ + GK + GH V ++W + S LLL+ S D T+ +W Sbjct: 112 EWILSGSYDKTSRIWS-LEGKSIMTIVGHTDVVKDVAWVKKDSLSCLLLTASMDQTILLW 170 Query: 307 D--IRARKLK--QDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 + I K+K GHA V A+ G K SG D+ LK+W Sbjct: 171 EWNIERNKVKALHCCRGHAGSVDAIAVDSSGTKFCSGSWDKMLKIW 216 Score = 45.1 bits (105), Expect = 2e-04 Identities = 36/100 (36%), Positives = 47/100 (47%), Gaps = 4/100 (4%) Frame = +1 Query: 10 RLVSGSDDFTMFLWEPTI--SKQPKARMTGHQKVVNHVYFSP-DGQWLASASFDKSVKLW 180 RL SGS D + LW+P +T H V V +SP Q L S S D VKLW Sbjct: 311 RLASGSTDRHIRLWDPRTKDGSLVSLSLTSHTGWVTSVKWSPTHDQQLISGSLDNMVKLW 370 Query: 181 NGITGKF-VTAFRGHVADVYQISWSADSRLLLSGSKDSTL 297 + + K + H V + W+ D+ LLLSG D+ L Sbjct: 371 DTRSCKAPLYDLAAHEDKVLSVDWT-DTGLLLSGGADNKL 409
>FBXW7_DROME (Q9VZF4) F-box/WD-repeat protein 7 (F-box and WD-40 domain protein 7)| (Protein archipelago) Length = 1326 Score = 72.0 bits (175), Expect = 1e-12 Identities = 48/141 (34%), Positives = 73/141 (51%) Frame = +1 Query: 10 RLVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGI 189 R+VSGSDD T+ +W K + + GH V S G + S S D+++K+W+ Sbjct: 1007 RIVSGSDDNTLKVWSAVNGKCLRT-LVGHTGGVWSSQMS--GNIIISGSTDRTLKVWDMD 1063 Query: 190 TGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAV 369 +G V +GH + V + ++SGS+D+TL+VWDI L GH V V Sbjct: 1064 SGACVHTLQGHTSTVRCMHLHGSK--VVSGSRDATLRVWDIEQGSCLHVLVGHLAAVRCV 1121 Query: 370 DWSPDGEKVVSGGKDRALKLW 432 + DG+ +VSG D +K+W Sbjct: 1122 QY--DGKLIVSGAYDYMVKIW 1140 Score = 70.9 bits (172), Expect = 3e-12 Identities = 41/128 (32%), Positives = 63/128 (49%) Frame = +1 Query: 49 WEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVA 228 W ++PK V+ + FS G + S S D ++K+W+ + GK + GH Sbjct: 979 WRSRPVRKPKVLKGHDDHVITCLQFS--GNRIVSGSDDNTLKVWSAVNGKCLRTLVGHTG 1036 Query: 229 DVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGG 408 V+ S + +++SGS D TLKVWD+ + L GH V + G KVVSG Sbjct: 1037 GVWSSQMSGN--IIISGSTDRTLKVWDMDSGACVHTLQGHTSTVRCMHL--HGSKVVSGS 1092 Query: 409 KDRALKLW 432 +D L++W Sbjct: 1093 RDATLRVW 1100 Score = 65.1 bits (157), Expect = 2e-10 Identities = 40/140 (28%), Positives = 74/140 (52%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 ++SGS D T+ +W+ S + GH V ++ G + S S D ++++W+ Sbjct: 1048 IISGSTDRTLKVWDMD-SGACVHTLQGHTSTVRCMHLH--GSKVVSGSRDATLRVWDIEQ 1104 Query: 193 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVD 372 G + GH+A V + + D +L++SG+ D +K+W ++ L GH + VY++ Sbjct: 1105 GSCLHVLVGHLAAVRCVQY--DGKLIVSGAYDYMVKIWHPERQECLHTLQGHTNRVYSLQ 1162 Query: 373 WSPDGEKVVSGGKDRALKLW 432 + DG VVSG D ++++W Sbjct: 1163 F--DGLHVVSGSLDTSIRVW 1180 Score = 60.1 bits (144), Expect = 5e-09 Identities = 43/143 (30%), Positives = 68/143 (47%), Gaps = 3/143 (2%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 +VSG+ D+ + +W P ++ + GH V + F DG + S S D S+++W+ T Sbjct: 1128 IVSGAYDYMVKIWHPE-RQECLHTLQGHTNRVYSLQF--DGLHVVSGSLDTSIRVWDVET 1184 Query: 193 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPG---HADEVY 363 G GH + +L+SG+ DST+KVWDI + Q L G H V Sbjct: 1185 GNCKHTLMGHQS--LTSGMELRQNILVSGNADSTVKVWDITTGQCLQTLSGPNKHHSAVT 1242 Query: 364 AVDWSPDGEKVVSGGKDRALKLW 432 + + + VV+ D +KLW Sbjct: 1243 CLQF--NSRFVVTSSDDGTVKLW 1263
>GBB_LOLFO (P23232) Guanine nucleotide-binding protein beta subunit| Length = 341 Score = 72.0 bits (175), Expect = 1e-12 Identities = 38/116 (32%), Positives = 63/116 (54%) Frame = +1 Query: 85 MTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSR 264 + GH ++ F D Q + ++S D + LWN TG +T+F GH DV +S + D R Sbjct: 140 LPGHTGYLSCCRFIDDNQ-IVTSSGDMTCALWNIETGNQITSFGGHTGDVMSLSLAPDMR 198 Query: 265 LLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 +SG+ D++ K++DIR KQ GH ++ A+ + P+G +G D +L+ Sbjct: 199 TFVSGACDASAKLFDIRDGICKQTFTGHESDINAITYFPNGFAFATGSDDATCRLF 254 Score = 58.2 bits (139), Expect = 2e-08 Identities = 33/121 (27%), Positives = 59/121 (48%), Gaps = 2/121 (1%) Frame = +1 Query: 76 KARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGH--VADVYQISW 249 K TGH+ +N + + P+G A+ S D + +L++ + + + + + +++ Sbjct: 220 KQTFTGHESDINAITYFPNGFAFATGSDDATCRLFDIRADQEIGMYSHDNIICGITSVAF 279 Query: 250 SADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKL 429 S RLLL G D VWD+ ++ L GH + V + + DG V +G D LK+ Sbjct: 280 SKSGRLLLGGYDDFNCNVWDVLKQERAGVLAGHDNRVSCLGVTEDGMAVATGSWDSFLKI 339 Query: 430 W 432 W Sbjct: 340 W 340 Score = 52.0 bits (123), Expect = 1e-06 Identities = 25/73 (34%), Positives = 38/73 (52%) Frame = +1 Query: 214 RGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEK 393 RGH+A +Y + W++DSR L+S S+D L VWD +P + V ++P G Sbjct: 53 RGHLAKIYAMHWASDSRNLVSASQDGKLIVWDGYTTNKVHAIPLRSSWVMTCAYAPSGNY 112 Query: 394 VVSGGKDRALKLW 432 V GG D ++ Sbjct: 113 VACGGLDNICSIY 125 Score = 45.1 bits (105), Expect = 2e-04 Identities = 33/133 (24%), Positives = 60/133 (45%), Gaps = 6/133 (4%) Frame = +1 Query: 52 EPTISKQPKARMT--GHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHV 225 EP Q + R T GH + ++++ D + L SAS D + +W+G T V A Sbjct: 39 EPVGRIQMRTRRTLRGHLAKIYAMHWASDSRNLVSASQDGKLIVWDGYTTNKVHAIPLRS 98 Query: 226 ADVYQISWSADSRLLLSGSKDSTLKVWDIRAR----KLKQDLPGHADEVYAVDWSPDGEK 393 + V +++ + G D+ ++ ++ R ++ ++LPGH + + D + Sbjct: 99 SWVMTCAYAPSGNYVACGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFIDDNQI 158 Query: 394 VVSGGKDRALKLW 432 V S G D LW Sbjct: 159 VTSSG-DMTCALW 170 Score = 38.1 bits (87), Expect = 0.020 Identities = 27/100 (27%), Positives = 45/100 (45%), Gaps = 3/100 (3%) Frame = +1 Query: 19 SGSDDFTMFLWEPTISKQPKARMTGHQKVV---NHVYFSPDGQWLASASFDKSVKLWNGI 189 +GSDD T L++ I + M H ++ V FS G+ L D + +W+ + Sbjct: 244 TGSDDATCRLFD--IRADQEIGMYSHDNIICGITSVAFSKSGRLLLGGYDDFNCNVWDVL 301 Query: 190 TGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWD 309 + GH V + + D + +GS DS LK+W+ Sbjct: 302 KQERAGVLAGHDNRVSCLGVTEDGMAVATGSWDSFLKIWN 341
>SCONB_EMENI (Q00659) Sulfur metabolite repression control protein| Length = 678 Score = 72.0 bits (175), Expect = 1e-12 Identities = 45/140 (32%), Positives = 71/140 (50%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 L +GS D T+ +W+ ++ + + GH+ + + F D L S S D+++K+WN T Sbjct: 362 LATGSYDTTIKIWDTETGEELRT-LRGHESGIRCLQF--DDTKLISGSMDRTIKVWNWRT 418 Query: 193 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVD 372 G+ ++ + GH V I D+ +L SGS D T+K+W+ K L GH D V AV Sbjct: 419 GECISTYTGHRGGV--IGLHFDASILASGSVDKTVKIWNFE-DKSTFSLRGHTDWVNAVR 475 Query: 373 WSPDGEKVVSGGKDRALKLW 432 V S D ++LW Sbjct: 476 VDTSSRTVFSASDDCTVRLW 495 Score = 61.2 bits (147), Expect = 2e-09 Identities = 40/120 (33%), Positives = 61/120 (50%) Frame = +1 Query: 10 RLVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGI 189 +L+SGS D T+ +W + + TGH+ V ++F D LAS S DK+VK+WN Sbjct: 401 KLISGSMDRTIKVWNWRTG-ECISTYTGHRGGVIGLHF--DASILASGSVDKTVKIWN-F 456 Query: 190 TGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAV 369 K + RGH V + SR + S S D T+++WD+ + + GH +V V Sbjct: 457 EDKSTFSLRGHTDWVNAVRVDTSSRTVFSASDDCTVRLWDLDTKTCIRTFHGHVGQVQQV 516 Score = 54.3 bits (129), Expect = 3e-07 Identities = 24/99 (24%), Positives = 56/99 (56%) Frame = +1 Query: 136 QWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIR 315 +++ +++ D +++LW TG+ + F GH+ V+ + AD+ ++SG++D +K+WD R Sbjct: 580 RYMVTSALDSTIRLWETTTGRCLRTFFGHLEGVWALG--ADTLRIVSGAEDRMIKIWDPR 637 Query: 316 ARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 K ++ GH+ V + + +G +D ++++ Sbjct: 638 TGKCERTFTGHSGPVTCIGLG--DSRFATGSEDCEVRMY 674 Score = 48.5 bits (114), Expect = 2e-05 Identities = 23/77 (29%), Positives = 42/77 (54%) Frame = +1 Query: 202 VTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSP 381 + F+GH V + + + +L +GS D+T+K+WD + + L GH + + + Sbjct: 342 IKTFKGHTNGVMCLQF--EDNILATGSYDTTIKIWDTETGEELRTLRGHESGIRCLQF-- 397 Query: 382 DGEKVVSGGKDRALKLW 432 D K++SG DR +K+W Sbjct: 398 DDTKLISGSMDRTIKVW 414 Score = 41.2 bits (95), Expect = 0.002 Identities = 18/61 (29%), Positives = 37/61 (60%) Frame = +1 Query: 250 SADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKL 429 +A R +++ + DST+++W+ + + GH + V+A+ D ++VSG +DR +K+ Sbjct: 576 AAPPRYMVTSALDSTIRLWETTTGRCLRTFFGHLEGVWAL--GADTLRIVSGAEDRMIKI 633 Query: 430 W 432 W Sbjct: 634 W 634
>CORO_YEAST (Q06440) Coronin-like protein| Length = 651 Score = 72.0 bits (175), Expect = 1e-12 Identities = 50/162 (30%), Positives = 80/162 (49%), Gaps = 21/162 (12%) Frame = +1 Query: 10 RLVSGSDDFTMFLWE---------------PTISKQPKARMTGHQKVVNHVYFSPDGQ-W 141 R+ SGSDD + +W+ I +P +TGH + V HV + P + Sbjct: 96 RIASGSDDSKIGIWDIPENYKFHDHVDEDGEPIDIKPVKFLTGHARKVGHVLYHPVAENV 155 Query: 142 LASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRAR 321 LAS+S D +VKLWN TGK + + H V +S+S D L + ++D L+VW+IR Sbjct: 156 LASSSGDYTVKLWNVETGKDMITLK-HPDMVTSMSFSYDGNYLATVARDKKLRVWNIREE 214 Query: 322 KLKQDLPGHAD-EVYAVDWSPDGEKVVSGG----KDRALKLW 432 K+ + P H + V W + +++ + G DR + +W Sbjct: 215 KIVSEGPAHTGAKNQRVVWLGNSDRLATTGFSKLSDRQIGIW 256
>COPB2_CAEEL (Q20168) Probable coatomer subunit beta' (Beta'-coat protein)| (Beta'-COP) Length = 1000 Score = 72.0 bits (175), Expect = 1e-12 Identities = 40/143 (27%), Positives = 70/143 (48%), Gaps = 3/143 (2%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSP-DGQWLASASFDKSVKLWNGI 189 ++S SDD + +W+ K GH V + +P D A+AS DK+VK+W Sbjct: 114 VISSSDDMLVKMWDWDNKWAMKQSFEGHTHYVMQIAINPKDNNTFATASLDKTVKVWQFG 173 Query: 190 TGKFVTAFRGHVADVYQISW--SADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVY 363 + GH V + + + ++SG+ D +K+WD + + Q L GHA V Sbjct: 174 SNVPNFTLEGHEKGVNCVDYYHGGEKPYIISGADDHLVKIWDYQNKTCVQTLDGHAQNVS 233 Query: 364 AVDWSPDGEKVVSGGKDRALKLW 432 +V + P+ +++G +D ++LW Sbjct: 234 SVCFHPELPLIITGSEDSTVRLW 256 Score = 50.8 bits (120), Expect = 3e-06 Identities = 34/134 (25%), Positives = 66/134 (49%), Gaps = 2/134 (1%) Frame = +1 Query: 19 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQ--WLASASFDKSVKLWNGIT 192 + S D T+ +W+ S P + GH+K VN V + G+ ++ S + D VK+W+ Sbjct: 160 TASLDKTVKVWQFG-SNVPNFTLEGHEKGVNCVDYYHGGEKPYIISGADDHLVKIWDYQN 218 Query: 193 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVD 372 V GH +V + + + L+++GS+DST+++W + + L + V+ + Sbjct: 219 KTCVQTLDGHAQNVSSVCFHPELPLIITGSEDSTVRLWHANTYRQEHTLNYGLERVWCIQ 278 Query: 373 WSPDGEKVVSGGKD 414 + G ++ G D Sbjct: 279 -AQKGANTIAIGYD 291 Score = 40.4 bits (93), Expect = 0.004 Identities = 26/119 (21%), Positives = 50/119 (42%) Frame = +1 Query: 76 KARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSA 255 K ++ V V P WL +A ++ +V +WN T V +F V + Sbjct: 8 KRKLLARSDRVKCVDLHPVETWLLAALYNGNVHIWNYETQTLVKSFEVCDVPVRAAKFVP 67 Query: 256 DSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 +++GS D ++V++ + H+D + ++ P V+S D +K+W Sbjct: 68 RKSWVVTGSDDMHIRVFNYNTLERVHQFEAHSDYLRSLVVHPTLPYVISSSDDMLVKMW 126
>GBB4_HUMAN (Q9HAV0) Guanine nucleotide-binding protein beta subunit 4| (Transducin beta chain 4) Length = 339 Score = 72.0 bits (175), Expect = 1e-12 Identities = 38/116 (32%), Positives = 61/116 (52%) Frame = +1 Query: 85 MTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSR 264 + GH ++ F D Q + ++S D + LW+ T + T F GH DV +S S D R Sbjct: 138 LPGHTGYLSCCRFLDDSQ-IVTSSGDTTCALWDIETAQQTTTFTGHSGDVMSLSLSPDMR 196 Query: 265 LLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 +SG+ D++ K+WDIR +Q GH ++ AV + P+G +G D +L+ Sbjct: 197 TFVSGACDASSKLWDIRDGMCRQSFTGHVSDINAVSFFPNGYAFATGSDDATCRLF 252 Score = 63.2 bits (152), Expect = 6e-10 Identities = 42/146 (28%), Positives = 75/146 (51%), Gaps = 5/146 (3%) Frame = +1 Query: 10 RLVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGI 189 ++V+ S D T LW+ ++Q TGH V + SPD + S + D S KLW+ Sbjct: 155 QIVTSSGDTTCALWDIETAQQTTT-FTGHSGDVMSLSLSPDMRTFVSGACDASSKLWDIR 213 Query: 190 TGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADE---- 357 G +F GHV+D+ +S+ + +GS D+T +++D+RA Q+L ++ + Sbjct: 214 DGMCRQSFTGHVSDINAVSFFPNGYAFATGSDDATCRLFDLRA---DQELLLYSHDNIIC 270 Query: 358 -VYAVDWSPDGEKVVSGGKDRALKLW 432 + +V +S G +++G D +W Sbjct: 271 GITSVAFSKSGRLLLAGYDDFNCNVW 296 Score = 53.9 bits (128), Expect = 4e-07 Identities = 25/73 (34%), Positives = 37/73 (50%) Frame = +1 Query: 214 RGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEK 393 RGH+A +Y + W DSRLL+S S+D L +WD +P + V ++P G Sbjct: 51 RGHLAKIYAMHWGYDSRLLVSASQDGKLIIWDSYTTNKMHAIPLRSSWVMTCAYAPSGNY 110 Query: 394 VVSGGKDRALKLW 432 V GG D ++ Sbjct: 111 VACGGLDNICSIY 123 Score = 42.0 bits (97), Expect = 0.001 Identities = 43/198 (21%), Positives = 68/198 (34%), Gaps = 46/198 (23%) Frame = +1 Query: 61 ISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT---------------- 192 I + + + GH + +++ D + L SAS D + +W+ T Sbjct: 42 IQMRTRRTLRGHLAKIYAMHWGYDSRLLVSASQDGKLIIWDSYTTNKMHAIPLRSSWVMT 101 Query: 193 ------GKFVTA------------------------FRGHVADVYQISWSADSRLLLSGS 282 G +V GH + + DS+++ S S Sbjct: 102 CAYAPSGNYVACGGLDNICSIYNLKTREGNVRVSRELPGHTGYLSCCRFLDDSQIVTS-S 160 Query: 283 KDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLWMN*ACL*YHH 462 D+T +WDI + GH+ +V ++ SPD VSG D + KLW Sbjct: 161 GDTTCALWDIETAQQTTTFTGHSGDVMSLSLSPDMRTFVSGACDASSKLW---------- 210 Query: 463 ECY*DDKCDDQFIEHVDD 516 D C F HV D Sbjct: 211 -DIRDGMCRQSFTGHVSD 227 Score = 37.7 bits (86), Expect = 0.027 Identities = 25/100 (25%), Positives = 46/100 (46%), Gaps = 3/100 (3%) Frame = +1 Query: 19 SGSDDFTMFLWEPTISKQPKARMTGHQKVV---NHVYFSPDGQWLASASFDKSVKLWNGI 189 +GSDD T L++ + + + H ++ V FS G+ L + D + +W+ + Sbjct: 242 TGSDDATCRLFD--LRADQELLLYSHDNIICGITSVAFSKSGRLLLAGYDDFNCNVWDTL 299 Query: 190 TGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWD 309 G GH V + + D + +GS DS L++W+ Sbjct: 300 KGDRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLRIWN 339
>MORG1_HUMAN (Q9BRX9) Mitogen-activated protein kinase organizer 1 (MAPK| organizer 1) Length = 315 Score = 71.6 bits (174), Expect = 2e-12 Identities = 33/112 (29%), Positives = 60/112 (53%) Frame = +1 Query: 97 QKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLLLS 276 Q V V F+ DG + + DK++KLWN + G + + GH +V + S D+ L S Sbjct: 25 QGAVRAVRFNVDGNYCLTCGSDKTLKLWNPLRGTLLRTYSGHGYEVLDAAGSFDNSSLCS 84 Query: 277 GSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 G D + +WD+ + ++ + GHA +V V ++ + ++SG D +++ W Sbjct: 85 GGGDKAVVLWDVASGQVVRKFRGHAGKVNTVQFNEEATVILSGSIDSSIRCW 136 Score = 62.4 bits (150), Expect = 1e-09 Identities = 37/104 (35%), Positives = 56/104 (53%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 L GSD T+ LW P + +GH V S D L S DK+V LW+ + Sbjct: 41 LTCGSDK-TLKLWNPLRGTLLRT-YSGHGYEVLDAAGSFDNSSLCSGGGDKAVVLWDVAS 98 Query: 193 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARK 324 G+ V FRGH V + ++ ++ ++LSGS DS+++ WD R+R+ Sbjct: 99 GQVVRKFRGHAGKVNTVQFNEEATVILSGSIDSSIRCWDCRSRR 142 Score = 37.7 bits (86), Expect = 0.027 Identities = 24/89 (26%), Positives = 44/89 (49%), Gaps = 2/89 (2%) Frame = +1 Query: 121 FSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSR--LLLSGSKDST 294 FS DGQ +S D +++L + TG+ + ++GH Y++ R ++S S+D Sbjct: 199 FSRDGQCTLVSSLDSTLRLLDKDTGELLGEYKGHKNQEYKLDCCLSERDTHVVSCSEDGK 258 Query: 295 LKVWDIRARKLKQDLPGHADEVYAVDWSP 381 + WD+ L LP + V ++ + P Sbjct: 259 VFFWDLVEGALALALPVGSGVVQSLAYHP 287
>ATG16_XENTR (Q5I0B9) Autophagy-related protein 16 (APG16-like 1)| Length = 537 Score = 71.6 bits (174), Expect = 2e-12 Identities = 39/115 (33%), Positives = 59/115 (51%), Gaps = 2/115 (1%) Frame = +1 Query: 94 HQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVT--AFRGHVADVYQISWSADSRL 267 H VN V FSP + LA+ D+ VKLW+ I K + G A + I + + Sbjct: 251 HDGEVNAVRFSPGSRLLATGGMDRRVKLWDVIGNKCEAKGSLTGSNAGITSIEFDSAGSY 310 Query: 268 LLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 LL+ S D ++W + +L+ L GH+ +V + + D ++VSG DR LKLW Sbjct: 311 LLAASNDFASRIWTVDDYRLRHTLTGHSGKVLSAKFLLDNARIVSGSHDRTLKLW 365 Score = 55.8 bits (133), Expect = 9e-08 Identities = 37/143 (25%), Positives = 70/143 (48%), Gaps = 3/143 (2%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISK-QPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGI 189 L +G D + LW+ +K + K +TG + + F G +L +AS D + ++W Sbjct: 267 LATGGMDRRVKLWDVIGNKCEAKGSLTGSNAGITSIEFDSAGSYLLAASNDFASRIWTVD 326 Query: 190 TGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARK-LKQDLPGHA-DEVY 363 + GH V + D+ ++SGS D TLK+WD+R++ +K G + +++ Sbjct: 327 DYRLRHTLTGHSGKVLSAKFLLDNARIVSGSHDRTLKLWDLRSKVCIKTVFAGSSCNDIV 386 Query: 364 AVDWSPDGEKVVSGGKDRALKLW 432 + + V+SG D+ ++ W Sbjct: 387 CTE-----QCVMSGHFDKKIRFW 404 Score = 47.0 bits (110), Expect = 4e-05 Identities = 41/145 (28%), Positives = 64/145 (44%), Gaps = 4/145 (2%) Frame = +1 Query: 10 RLVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGI 189 R+VSGS D T+ LW+ K G N + + Q + S FDK ++ W+ Sbjct: 352 RIVSGSHDRTLKLWDLRSKVCIKTVFAGSS--CNDIVCTE--QCVMSGHFDKKIRFWDIR 407 Query: 190 TGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQ--DLPGH--ADE 357 T V + + + + LLS S+D +K+ D+RA ++Q PG + Sbjct: 408 TECIVRELELQ-GRITALDLNPERTQLLSCSRDDLIKITDLRANAVQQTFSAPGFKCGSD 466 Query: 358 VYAVDWSPDGEKVVSGGKDRALKLW 432 V +SPDG V +G + L W Sbjct: 467 WTRVIFSPDGSYVSAGSAEGTLYFW 491 Score = 42.0 bits (97), Expect = 0.001 Identities = 20/65 (30%), Positives = 36/65 (55%), Gaps = 1/65 (1%) Frame = +1 Query: 115 VYFSPDGQWLASASFDKSVKLWNGITGKFVTAF-RGHVADVYQISWSADSRLLLSGSKDS 291 V FSPDG ++++ S + ++ WN +TGK F + H + + ++WS ++S K S Sbjct: 470 VIFSPDGSYVSAGSAEGTLYFWNVLTGKVERMFSKQHSSSINAVAWSPSGTHVVSVDKGS 529 Query: 292 TLKVW 306 +W Sbjct: 530 RGVLW 534 Score = 41.6 bits (96), Expect = 0.002 Identities = 37/145 (25%), Positives = 63/145 (43%), Gaps = 5/145 (3%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLW---- 180 ++SG D + W+ I + R Q + + +P+ L S S D +K+ Sbjct: 392 VMSGHFDKKIRFWD--IRTECIVRELELQGRITALDLNPERTQLLSCSRDDLIKITDLRA 449 Query: 181 NGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPG-HADE 357 N + F +D ++ +S D + +GS + TL W++ K+++ H+ Sbjct: 450 NAVQQTFSAPGFKCGSDWTRVIFSPDGSYVSAGSAEGTLYFWNVLTGKVERMFSKQHSSS 509 Query: 358 VYAVDWSPDGEKVVSGGKDRALKLW 432 + AV WSP G VVS K LW Sbjct: 510 INAVAWSPSGTHVVSVDKGSRGVLW 534
>YAGE_SCHPO (Q9UTN4) Hypothetical WD-repeat protein C12G12.14c in chromosome I| Length = 509 Score = 71.2 bits (173), Expect = 2e-12 Identities = 47/138 (34%), Positives = 72/138 (52%), Gaps = 3/138 (2%) Frame = +1 Query: 10 RLVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGI 189 + V+ SDD ++ +W +S + + ++TGH V V + P LAS S D VK W+ Sbjct: 178 KFVTASDDGSLKVWNFHMSTE-ELKLTGHGWDVKTVDWHPSKGLLASGSKDNLVKFWDPR 236 Query: 190 TGKFVTAFRGHVADVYQISWSAD--SRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVY 363 TG + GH + Q S+ + S L + S+DST +V+D+RA K + L GH +V Sbjct: 237 TGTCIATLHGHKNTIMQASFQKNFGSNYLATVSRDSTCRVFDLRAMKDVRVLRGHEKDVN 296 Query: 364 AVDWSP-DGEKVVSGGKD 414 V W P + +GG D Sbjct: 297 CVTWHPLYPNLLTTGGSD 314 Score = 63.5 bits (153), Expect = 5e-10 Identities = 43/151 (28%), Positives = 57/151 (37%), Gaps = 41/151 (27%) Frame = +1 Query: 103 VVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLLLSG- 279 V+N V ++PDG+ L + S LWNG+T F + H V WS D R L+SG Sbjct: 83 VINVVRWTPDGRRLLTGSSTGEFTLWNGLTFNFELINQSHDYAVRCAEWSTDGRWLISGD 142 Query: 280 ----------------------------------------SKDSTLKVWDIRARKLKQDL 339 S D +LKVW+ + L Sbjct: 143 GGGMVKYFEPNLNNVKIVQAHEMEVRDVAFSPNDSKFVTASDDGSLKVWNFHMSTEELKL 202 Query: 340 PGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 GH +V VDW P + SG KD +K W Sbjct: 203 TGHGWDVKTVDWHPSKGLLASGSKDNLVKFW 233 Score = 60.1 bits (144), Expect = 5e-09 Identities = 37/116 (31%), Positives = 53/116 (45%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 L+SG + +EP ++ + H+ V V FSP+ +AS D S+K+WN Sbjct: 138 LISGDGGGMVKYFEPNLNNVKIVQ--AHEMEVRDVAFSPNDSKFVTASDDGSLKVWNFHM 195 Query: 193 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEV 360 GH DV + W LL SGSKD+ +K WD R L GH + + Sbjct: 196 STEELKLTGHGWDVKTVDWHPSKGLLASGSKDNLVKFWDPRTGTCIATLHGHKNTI 251
>HIRA_DROME (O17468) HIRA protein homolog (dHIRA)| Length = 1047 Score = 71.2 bits (173), Expect = 2e-12 Identities = 55/166 (33%), Positives = 76/166 (45%), Gaps = 29/166 (17%) Frame = +1 Query: 22 GSDDFTMFLWE--PTISKQ-------PK--ARMTGHQKVVNHVYFSPDGQWLASASFDKS 168 GSD + +W P +S + PK +M H VN V +S +GQ LAS S DK Sbjct: 34 GSDCGRVVIWNLLPVLSDKAEFDADVPKMLCQMDQHLACVNCVRWSQNGQNLASGSDDKL 93 Query: 169 VKLWN---GITGKFVTA--------------FRGHVADVYQISWSADSRLLLSGSKDSTL 297 + +W G +G F T RGH DV ++WS + L S S D+T+ Sbjct: 94 IMIWRKSAGSSGVFGTGGMQKNHESWKCFYTLRGHDGDVLDLAWSPNDVYLASCSIDNTV 153 Query: 298 KVWDIRA-RKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 +WD +A L GH V V W P G + S DR++K+W Sbjct: 154 IIWDAQAFPHSVATLKGHTGLVKGVSWDPLGRFLASQSDDRSIKIW 199 Score = 60.1 bits (144), Expect = 5e-09 Identities = 42/153 (27%), Positives = 67/153 (43%), Gaps = 23/153 (15%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPT-----------ISKQPKA-----RMTGHQKVVNHVYFSPDGQWL 144 L SGSDD + +W + + K ++ + GH V + +SP+ +L Sbjct: 85 LASGSDDKLIMIWRKSAGSSGVFGTGGMQKNHESWKCFYTLRGHDGDVLDLAWSPNDVYL 144 Query: 145 ASASFDKSVKLWNG-ITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRAR 321 AS S D +V +W+ V +GH V +SW R L S S D ++K+W+ Sbjct: 145 ASCSIDNTVIIWDAQAFPHSVATLKGHTGLVKGVSWDPLGRFLASQSDDRSIKIWNTMNW 204 Query: 322 KLKQDLP------GHADEVYAVDWSPDGEKVVS 402 L + G + + WSPDG+ +VS Sbjct: 205 SLSHTITEPFEECGGTTHILRLSWSPDGQYLVS 237 Score = 58.5 bits (140), Expect = 1e-08 Identities = 46/167 (27%), Positives = 72/167 (43%), Gaps = 26/167 (15%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWN--- 183 L S S D T+ +W+ A + GH +V V + P G++LAS S D+S+K+WN Sbjct: 144 LASCSIDNTVIIWDAQAFPHSVATLKGHTGLVKGVSWDPLGRFLASQSDDRSIKIWNTMN 203 Query: 184 -GITGKFVTAFR--GHVADVYQISWSADSRLLLS----GSKDSTLKVWDIRARKLKQDLP 342 ++ F G + ++SWS D + L+S T ++ + K +D Sbjct: 204 WSLSHTITEPFEECGGTTHILRLSWSPDGQYLVSAHAMNGGGPTAQIIEREGWKCDKDFV 263 Query: 343 GHADEVYAV------------DWSPDGEK----VVSGGKDRALKLWM 435 GH V V D SP + G +DR+L +WM Sbjct: 264 GHRKAVTCVRFHNSILSRQENDGSPSKPLQYCCLAVGSRDRSLSVWM 310
>GBB_MAIZE (P49178) Guanine nucleotide-binding protein beta subunit| Length = 380 Score = 71.2 bits (173), Expect = 2e-12 Identities = 42/124 (33%), Positives = 74/124 (59%), Gaps = 8/124 (6%) Frame = +1 Query: 85 MTGHQKVVNHVYFSPDGQW-LASASFDKSVKLWNGITGKFVTAF-----RGHVADVYQIS 246 +TGH+ V+ + PD + L ++S D++ LW+ TG+ ++ F GH ADV +S Sbjct: 153 LTGHKGYVSSCQYVPDQETRLITSSGDQTCVLWDVTTGQRISIFGGEFPSGHTADVQSVS 212 Query: 247 W-SADSRLLLSGSKDSTLKVWDIR-ARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRA 420 S+++ + +SGS D+T+++WDIR A + + GH D+V +V + PDG + +G D Sbjct: 213 INSSNTNMFVSGSCDTTVRLWDIRIASRAVRTYHGHEDDVNSVKFFPDGHRFGTGSDDGT 272 Query: 421 LKLW 432 +L+ Sbjct: 273 CRLF 276 Score = 63.5 bits (153), Expect = 5e-10 Identities = 43/150 (28%), Positives = 69/150 (46%), Gaps = 11/150 (7%) Frame = +1 Query: 16 VSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITG 195 VSGS D T+ LW+ I+ + GH+ VN V F PDG + S D + +L++ TG Sbjct: 222 VSGSCDTTVRLWDIRIASRAVRTYHGHEDDVNSVKFFPDGHRFGTGSDDGTCRLFDMRTG 281 Query: 196 KFVTAF-------RGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDL----P 342 + + + V I++S RLL +G + VWD ++ +L Sbjct: 282 HQLQVYSREPDRNSNELPTVTSIAFSISGRLLFAGYSNGDCYVWDTLLAEVVLNLGNLQN 341 Query: 343 GHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 H + + S DG + +G D+ LK+W Sbjct: 342 SHDGRISCLGMSSDGSALCTGSWDKNLKIW 371 Score = 48.5 bits (114), Expect = 2e-05 Identities = 28/124 (22%), Positives = 60/124 (48%), Gaps = 8/124 (6%) Frame = +1 Query: 85 MTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSR 264 + GH V + ++P+ W+ SAS D + +WN +T + A + H V +++ + + Sbjct: 62 LQGHSGKVYSLDWTPEKNWIVSASQDGRLIVWNALTSQKTHAIKLHCPWVMACAFAPNGQ 121 Query: 265 LLLSGSKDSTLKVWDIRAR-------KLKQDLPGHADEVYAVDWSPDGE-KVVSGGKDRA 420 + G DS ++++ ++ + + L GH V + + PD E ++++ D+ Sbjct: 122 SVACGGLDSACSIFNLNSQADRDGNMPVSRILTGHKGYVSSCQYVPDQETRLITSSGDQT 181 Query: 421 LKLW 432 LW Sbjct: 182 CVLW 185 Score = 47.8 bits (112), Expect = 3e-05 Identities = 38/125 (30%), Positives = 57/125 (45%), Gaps = 6/125 (4%) Frame = +1 Query: 10 RLVSGSDDFTMFLWEPT----ISKQPKARMTGHQKVVNHVYF-SPDGQWLASASFDKSVK 174 RL++ S D T LW+ T IS +GH V V S + S S D +V+ Sbjct: 172 RLITSSGDQTCVLWDVTTGQRISIFGGEFPSGHTADVQSVSINSSNTNMFVSGSCDTTVR 231 Query: 175 LWN-GITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHA 351 LW+ I + V + GH DV + + D +GS D T +++D+R GH Sbjct: 232 LWDIRIASRAVRTYHGHEDDVNSVKFFPDGHRFGTGSDDGTCRLFDMRT--------GHQ 283 Query: 352 DEVYA 366 +VY+ Sbjct: 284 LQVYS 288
>MORG1_BRARE (Q6DH44) Mitogen-activated protein kinase organizer 1 (MAPK| organizer 1) Length = 315 Score = 71.2 bits (173), Expect = 2e-12 Identities = 36/112 (32%), Positives = 60/112 (53%) Frame = +1 Query: 97 QKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLLLS 276 Q V V F+ DG +L + DKS+KLW+ G + + GH +V S D+ L S Sbjct: 25 QGAVRAVRFNADGNYLLTCGSDKSLKLWSVSRGTLLKTYSGHGYEVLDADGSYDNSQLCS 84 Query: 277 GSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 S D T+ +WD+ + ++ + L GHA +V V ++ + ++SG D ++ W Sbjct: 85 CSSDKTVILWDVASGQVTRKLRGHAGKVNCVQFNEEATVMLSGSIDGTVRCW 136 Score = 57.8 bits (138), Expect = 2e-08 Identities = 39/125 (31%), Positives = 62/125 (49%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 L GSD ++ LW + K +GH V S D L S S DK+V LW+ + Sbjct: 41 LTCGSDK-SLKLWSVSRGTLLKT-YSGHGYEVLDADGSYDNSQLCSCSSDKTVILWDVAS 98 Query: 193 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVD 372 G+ RGH V + ++ ++ ++LSGS D T++ WD R+R++ + + +D Sbjct: 99 GQVTRKLRGHAGKVNCVQFNEEATVMLSGSIDGTVRCWDTRSRRM--------EPIQILD 150 Query: 373 WSPDG 387 S DG Sbjct: 151 ESQDG 155 Score = 44.3 bits (103), Expect = 3e-04 Identities = 30/108 (27%), Positives = 55/108 (50%), Gaps = 2/108 (1%) Frame = +1 Query: 115 VYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSR--LLLSGSKD 288 V FS DGQ S+S D +V+L + TG+ + + GHV Y++ + +LS S+D Sbjct: 197 VCFSRDGQCTLSSSLDSTVRLLDKSTGEMLGEYSGHVNKGYKLDCCLTDKDTHVLSCSED 256 Query: 289 STLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 + WD+ L LP V ++ + P ++++ + R +++W Sbjct: 257 GHVYYWDLVEGSLTLKLPVGKAVVQSLSFHPTEPRLLTSMEGR-VQVW 303
>MORG1_XENTR (Q5XGI5) Mitogen-activated protein kinase organizer 1 (MAPK| organizer 1) Length = 314 Score = 70.9 bits (172), Expect = 3e-12 Identities = 34/126 (26%), Positives = 67/126 (53%) Frame = +1 Query: 55 PTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADV 234 P + ++ + ++ +Q V V F+ DG + + DK++KLWN G + + GH +V Sbjct: 11 PELPQKLQHKLECNQGAVRAVRFNVDGNYCMTCGSDKTLKLWNPHKGTLLKTYSGHGYEV 70 Query: 235 YQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKD 414 + S D+ + S S D T+ +WD+ ++ + GHA +V V ++ + ++SG D Sbjct: 71 LDTAGSYDNSQMCSCSSDKTVILWDVAQGQVVRKFRGHAGKVNCVQFNEEATVIMSGSID 130 Query: 415 RALKLW 432 +++ W Sbjct: 131 SSIRCW 136 Score = 61.6 bits (148), Expect = 2e-09 Identities = 36/104 (34%), Positives = 56/104 (53%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 + GSD T+ LW P K +GH V S D + S S DK+V LW+ Sbjct: 41 MTCGSDK-TLKLWNPHKGTLLKT-YSGHGYEVLDTAGSYDNSQMCSCSSDKTVILWDVAQ 98 Query: 193 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARK 324 G+ V FRGH V + ++ ++ +++SGS DS+++ WD R+R+ Sbjct: 99 GQVVRKFRGHAGKVNCVQFNEEATVIMSGSIDSSIRCWDCRSRR 142 Score = 43.5 bits (101), Expect = 5e-04 Identities = 44/185 (23%), Positives = 73/185 (39%), Gaps = 44/185 (23%) Frame = +1 Query: 10 RLVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWN-- 183 ++ S S D T+ LW+ Q + GH VN V F+ + + S S D S++ W+ Sbjct: 81 QMCSCSSDKTVILWD-VAQGQVVRKFRGHAGKVNCVQFNEEATVIMSGSIDSSIRCWDCR 139 Query: 184 ---------------GIT-------------------------GKFVTAFRGHVADVYQI 243 GI+ G+ + G + + + Sbjct: 140 SRRPEAIQILDEAKDGISSIKISDHEILAGSVDGNLRRYDLRKGEMCADYLG--SPITCV 197 Query: 244 SWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVD--WSPDGEKVVSGGKDR 417 S+S DS+ LL+ S DSTL++ D +L + GH + Y +D S V+S +D Sbjct: 198 SFSQDSQCLLASSLDSTLRLLDKDTGELLGEYTGHQNHSYKLDSCLSEKDTHVLSCSEDG 257 Query: 418 ALKLW 432 + W Sbjct: 258 TVCFW 262
>COPB2_DROME (O62621) Coatomer subunit beta' (Beta'-coat protein) (Beta'-COP)| Length = 914 Score = 70.9 bits (172), Expect = 3e-12 Identities = 42/143 (29%), Positives = 70/143 (48%), Gaps = 3/143 (2%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSP-DGQWLASASFDKSVKLWNGI 189 +++ SDD + LW + GH V + F+P D ASAS D++VK+W Sbjct: 114 VLTSSDDMLIKLWNWEKMWACQRVFEGHTHYVMQIVFNPKDNNTFASASLDRTVKVWQLG 173 Query: 190 TGKFVTAFRGHVADVYQISW--SADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVY 363 + GH V + + D L+SG+ D +K+WD + + Q L GHA + Sbjct: 174 SNFANFTLEGHEKGVNCVDYYHGGDKPYLISGADDRLVKIWDYQNKTCVQTLEGHAQNIS 233 Query: 364 AVDWSPDGEKVVSGGKDRALKLW 432 AV + P+ V++G +D +++W Sbjct: 234 AVCFHPELPIVLTGSEDGTVRIW 256 Score = 50.4 bits (119), Expect = 4e-06 Identities = 37/134 (27%), Positives = 65/134 (48%), Gaps = 2/134 (1%) Frame = +1 Query: 19 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHV--YFSPDGQWLASASFDKSVKLWNGIT 192 S S D T+ +W+ S + GH+K VN V Y D +L S + D+ VK+W+ Sbjct: 160 SASLDRTVKVWQLG-SNFANFTLEGHEKGVNCVDYYHGGDKPYLISGADDRLVKIWDYQN 218 Query: 193 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVD 372 V GH ++ + + + ++L+GS+D T+++W +L+ L + V+ + Sbjct: 219 KTCVQTLEGHAQNISAVCFHPELPIVLTGSEDGTVRIWHSGTYRLETCLNYGFERVWTIS 278 Query: 373 WSPDGEKVVSGGKD 414 S G V+ G D Sbjct: 279 -SMRGTNNVALGYD 291 Score = 40.0 bits (92), Expect = 0.005 Identities = 27/119 (22%), Positives = 47/119 (39%) Frame = +1 Query: 76 KARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSA 255 K R+T V V P W+ A ++ V + N + V F V + A Sbjct: 8 KRRLTSRSDRVKCVDLHPAEPWMLCALYNGHVHIMNYENQQMVKDFEVCDVPVRSARFVA 67 Query: 256 DSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 +L+GS D ++V++ + H+D + + P V++ D +KLW Sbjct: 68 RKNWILTGSDDMQIRVFNYNTLEKVHSFEAHSDYLRCIAVHPTQPLVLTSSDDMLIKLW 126
>WDR39_HUMAN (O76071) WD-repeat protein 39 (Ciao 1 protein)| Length = 339 Score = 70.9 bits (172), Expect = 3e-12 Identities = 40/119 (33%), Positives = 60/119 (50%), Gaps = 5/119 (4%) Frame = +1 Query: 91 GHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKF--VTAFRGHVADVYQISWSADSR 264 GHQ+ V V +SP G +LASASFD + +W F VT GH +V ++W+ Sbjct: 59 GHQRTVRKVAWSPCGNYLASASFDATTCIWKKNQDDFECVTTLEGHENEVKSVAWAPSGN 118 Query: 265 LLLSGSKDSTLKVWDIRAR---KLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 LL + S+D ++ VW++ + L H +V V W P E + S D +KL+ Sbjct: 119 LLATCSRDKSVWVWEVDEEDEYECVSVLNSHTQDVKHVVWHPSQELLASASYDDTVKLY 177 Score = 67.4 bits (163), Expect = 3e-11 Identities = 44/150 (29%), Positives = 71/150 (47%), Gaps = 10/150 (6%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISK-QPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLW--- 180 L S S D T +W+ + + GH+ V V ++P G LA+ S DKSV +W Sbjct: 76 LASASFDATTCIWKKNQDDFECVTTLEGHENEVKSVAWAPSGNLLATCSRDKSVWVWEVD 135 Query: 181 NGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQD------LP 342 + V+ H DV + W LL S S D T+K++ R+ + D L Sbjct: 136 EEDEYECVSVLNSHTQDVKHVVWHPSQELLASASYDDTVKLY----REEEDDWVCCATLE 191 Query: 343 GHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 GH V+++ + P G+++ S DR +++W Sbjct: 192 GHESTVWSLAFDPSGQRLASCSDDRTVRIW 221 Score = 54.7 bits (130), Expect = 2e-07 Identities = 32/114 (28%), Positives = 55/114 (48%), Gaps = 10/114 (8%) Frame = +1 Query: 121 FSPDGQWLASASFDKSVKLWNGITGKFV---TAFRGHVADVYQISWSADSRLLLSGSKDS 291 ++P G LAS D+ +++W ++ GH V +++WS L S S D+ Sbjct: 24 WNPAGTLLASCGGDRRIRIWGTEGDSWICKSVLSEGHQRTVRKVAWSPCGNYLASASFDA 83 Query: 292 TLKVWDIRARKLKQD-------LPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 T +W K QD L GH +EV +V W+P G + + +D+++ +W Sbjct: 84 TTCIW-----KKNQDDFECVTTLEGHENEVKSVAWAPSGNLLATCSRDKSVWVW 132 Score = 50.4 bits (119), Expect = 4e-06 Identities = 34/120 (28%), Positives = 61/120 (50%), Gaps = 4/120 (3%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPK--ARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNG 186 L + S D ++++WE + + + + H + V HV + P + LASAS+D +VKL+ Sbjct: 120 LATCSRDKSVWVWEVDEEDEYECVSVLNSHTQDVKHVVWHPSQELLASASYDDTVKLYRE 179 Query: 187 ITGKFV--TAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEV 360 +V GH + V+ +++ + L S S D T+++W +Q LPG+ V Sbjct: 180 EEDDWVCCATLEGHESTVWSLAFDPSGQRLASCSDDRTVRIW-------RQYLPGNEQGV 232 Score = 39.7 bits (91), Expect = 0.007 Identities = 31/126 (24%), Positives = 51/126 (40%), Gaps = 25/126 (19%) Frame = +1 Query: 79 ARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLW--------NGI-------TGKFVTAF 213 A + GH+ V + F P GQ LAS S D++V++W G+ + K + Sbjct: 188 ATLEGHESTVWSLAFDPSGQRLASCSDDRTVRIWRQYLPGNEQGVACSGSDPSWKCICTL 247 Query: 214 RG-HVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQD---------LPGHADEVY 363 G H +Y I+W + L + D ++V+ Q H+ +V Sbjct: 248 SGFHSRTIYDIAWCQLTGALATACGDDAIRVFQEDPNSDPQQPTFSLTAHLHQAHSQDVN 307 Query: 364 AVDWSP 381 V W+P Sbjct: 308 CVAWNP 313
>TAF5_SCHPO (O13282) Transcription initiation factor TFIID subunit 5| (Transcription initiation factor TFIID 72 kDa subunit) (TAFII-72) Length = 643 Score = 70.9 bits (172), Expect = 3e-12 Identities = 35/101 (34%), Positives = 60/101 (59%), Gaps = 1/101 (0%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARM-TGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGI 189 +++GS D T LW+ + + R+ GH + V V +PDG +ASA + + LW+ Sbjct: 478 VLTGSSDKTCRLWD--VHRGHSVRVFNGHTQPVTAVAIAPDGHTMASADSEGLIHLWDIG 535 Query: 190 TGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDI 312 TG+ + RGH ++Y +S+S +S +L+SG D T++ WD+ Sbjct: 536 TGRRIKTMRGHRGNIYSLSFSRESTVLVSGGSDCTVRAWDV 576 Score = 70.5 bits (171), Expect = 4e-12 Identities = 38/138 (27%), Positives = 65/138 (47%) Frame = +1 Query: 19 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 198 + S D T LW P GH V+ V F P+ ++ + S DK+ +LW+ G Sbjct: 438 TASHDQTAQLWSCD-HIYPLRVFAGHLSDVDCVTFHPNSAYVLTGSSDKTCRLWDVHRGH 496 Query: 199 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWS 378 V F GH V ++ + D + S + + +WDI + + + GH +Y++ +S Sbjct: 497 SVRVFNGHTQPVTAVAIAPDGHTMASADSEGLIHLWDIGTGRRIKTMRGHRGNIYSLSFS 556 Query: 379 PDGEKVVSGGKDRALKLW 432 + +VSGG D ++ W Sbjct: 557 RESTVLVSGGSDCTVRAW 574 Score = 66.2 bits (160), Expect = 7e-11 Identities = 33/117 (28%), Positives = 56/117 (47%) Frame = +1 Query: 82 RMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADS 261 R+ H V FSPD ++L S S D S +LW+ T + A++GH V+ +++ Sbjct: 374 RLLSHSGPVYGTTFSPDNKYLLSCSEDASARLWSVDTKTALVAYKGHTGPVWDVAFGPFG 433 Query: 262 RLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 + S D T ++W + GH +V V + P+ V++G D+ +LW Sbjct: 434 HYFATASHDQTAQLWSCDHIYPLRVFAGHLSDVDCVTFHPNSAYVLTGSSDKTCRLW 490 Score = 47.4 bits (111), Expect = 3e-05 Identities = 29/122 (23%), Positives = 51/122 (41%), Gaps = 13/122 (10%) Frame = +1 Query: 106 VNHVYFSPDGQWLASASFDKSVKLWNGITGK-------------FVTAFRGHVADVYQIS 246 +N FSPD +A + ++LW+ K H VY + Sbjct: 327 MNCAEFSPDSTMIACGFQESYIRLWSIKADKKSLPKSTSVEDSDGSVRLLSHSGPVYGTT 386 Query: 247 WSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALK 426 +S D++ LLS S+D++ ++W + + GH V+ V + P G + D+ + Sbjct: 387 FSPDNKYLLSCSEDASARLWSVDTKTALVAYKGHTGPVWDVAFGPFGHYFATASHDQTAQ 446 Query: 427 LW 432 LW Sbjct: 447 LW 448 Score = 32.7 bits (73), Expect = 0.86 Identities = 21/92 (22%), Positives = 39/92 (42%), Gaps = 12/92 (13%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWN--- 183 + S + + LW+ ++ K M GH+ + + FS + L S D +V+ W+ Sbjct: 520 MASADSEGLIHLWDIGTGRRIKT-MRGHRGNIYSLSFSRESTVLVSGGSDCTVRAWDVFK 578 Query: 184 ---------GITGKFVTAFRGHVADVYQISWS 252 +TG VT F + +++WS Sbjct: 579 TNYNNPVSSSLTGSVVTPFSAKTSTFNEVNWS 610
>GBB2_RAT (P54313) Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta| subunit 2 (Transducin beta chain 2) (G protein beta 2 subunit) Length = 339 Score = 70.5 bits (171), Expect = 4e-12 Identities = 36/116 (31%), Positives = 61/116 (52%) Frame = +1 Query: 85 MTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSR 264 + GH ++ F D Q + S+ D + LW+ TG+ F GH DV +S + D R Sbjct: 138 LPGHTGYLSCCRFLDDNQIITSSG-DTTCALWDIETGQQTVGFAGHSGDVMSLSLAPDGR 196 Query: 265 LLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 +SG+ D+++K+WD+R +Q GH ++ AV + P+G +G D +L+ Sbjct: 197 TFVSGACDASIKLWDVRDSMCRQTFIGHESDINAVAFFPNGYAFTTGSDDATCRLF 252 Score = 58.2 bits (139), Expect = 2e-08 Identities = 37/146 (25%), Positives = 72/146 (49%), Gaps = 5/146 (3%) Frame = +1 Query: 10 RLVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGI 189 ++++ S D T LW+ +Q GH V + +PDG+ S + D S+KLW+ Sbjct: 155 QIITSSGDTTCALWDIETGQQTVG-FAGHSGDVMSLSLAPDGRTFVSGACDASIKLWDVR 213 Query: 190 TGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADE---- 357 F GH +D+ +++ + +GS D+T +++D+RA Q+L ++ + Sbjct: 214 DSMCRQTFIGHESDINAVAFFPNGYAFTTGSDDATCRLFDLRA---DQELLMYSHDNIIC 270 Query: 358 -VYAVDWSPDGEKVVSGGKDRALKLW 432 + +V +S G +++G D +W Sbjct: 271 GITSVAFSRSGRLLLAGYDDFNCNIW 296 Score = 57.8 bits (138), Expect = 2e-08 Identities = 38/141 (26%), Positives = 66/141 (46%), Gaps = 2/141 (1%) Frame = +1 Query: 16 VSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITG 195 VSG+ D ++ LW+ S + GH+ +N V F P+G + S D + +L++ Sbjct: 199 VSGACDASIKLWDVRDS-MCRQTFIGHESDINAVAFFPNGYAFTTGSDDATCRLFDLRAD 257 Query: 196 KFVTAFRGH--VADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAV 369 + + + + + +++S RLLL+G D +WD L GH + V + Sbjct: 258 QELLMYSHDNIICGITSVAFSRSGRLLLAGYDDFNCNIWDAMKGDRAGVLAGHDNRVSCL 317 Query: 370 DWSPDGEKVVSGGKDRALKLW 432 + DG V +G D LK+W Sbjct: 318 GVTDDGMAVATGSWDSFLKIW 338 Score = 53.9 bits (128), Expect = 4e-07 Identities = 25/73 (34%), Positives = 37/73 (50%) Frame = +1 Query: 214 RGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEK 393 RGH+A +Y + W DSRLL+S S+D L +WD +P + V ++P G Sbjct: 51 RGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNF 110 Query: 394 VVSGGKDRALKLW 432 V GG D ++ Sbjct: 111 VACGGLDNICSIY 123 Score = 46.6 bits (109), Expect = 6e-05 Identities = 41/197 (20%), Positives = 69/197 (35%), Gaps = 45/197 (22%) Frame = +1 Query: 61 ISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT---------------- 192 I + + + GH + +++ D + L SAS D + +W+ T Sbjct: 42 IQMRTRRTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMT 101 Query: 193 ------GKFVT-AFRGHVADVYQISWS----------------------ADSRLLLSGSK 285 G FV ++ +Y + D +++ S Sbjct: 102 CAYAPSGNFVACGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFLDDNQIITSSG 161 Query: 286 DSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLWMN*ACL*YHHE 465 D+T +WDI + GH+ +V ++ +PDG VSG D ++KLW Sbjct: 162 DTTCALWDIETGQQTVGFAGHSGDVMSLSLAPDGRTFVSGACDASIKLW----------- 210 Query: 466 CY*DDKCDDQFIEHVDD 516 D C FI H D Sbjct: 211 DVRDSMCRQTFIGHESD 227 Score = 40.4 bits (93), Expect = 0.004 Identities = 27/100 (27%), Positives = 46/100 (46%), Gaps = 3/100 (3%) Frame = +1 Query: 19 SGSDDFTMFLWEPTISKQPKARMTGHQKVV---NHVYFSPDGQWLASASFDKSVKLWNGI 189 +GSDD T L++ + + M H ++ V FS G+ L + D + +W+ + Sbjct: 242 TGSDDATCRLFD--LRADQELLMYSHDNIICGITSVAFSRSGRLLLAGYDDFNCNIWDAM 299 Query: 190 TGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWD 309 G GH V + + D + +GS DS LK+W+ Sbjct: 300 KGDRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN 339
>GBB2_MOUSE (P62880) Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta| subunit 2 (Transducin beta chain 2) (G protein beta 2 subunit) Length = 339 Score = 70.5 bits (171), Expect = 4e-12 Identities = 36/116 (31%), Positives = 61/116 (52%) Frame = +1 Query: 85 MTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSR 264 + GH ++ F D Q + S+ D + LW+ TG+ F GH DV +S + D R Sbjct: 138 LPGHTGYLSCCRFLDDNQIITSSG-DTTCALWDIETGQQTVGFAGHSGDVMSLSLAPDGR 196 Query: 265 LLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 +SG+ D+++K+WD+R +Q GH ++ AV + P+G +G D +L+ Sbjct: 197 TFVSGACDASIKLWDVRDSMCRQTFIGHESDINAVAFFPNGYAFTTGSDDATCRLF 252 Score = 58.2 bits (139), Expect = 2e-08 Identities = 37/146 (25%), Positives = 72/146 (49%), Gaps = 5/146 (3%) Frame = +1 Query: 10 RLVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGI 189 ++++ S D T LW+ +Q GH V + +PDG+ S + D S+KLW+ Sbjct: 155 QIITSSGDTTCALWDIETGQQTVG-FAGHSGDVMSLSLAPDGRTFVSGACDASIKLWDVR 213 Query: 190 TGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADE---- 357 F GH +D+ +++ + +GS D+T +++D+RA Q+L ++ + Sbjct: 214 DSMCRQTFIGHESDINAVAFFPNGYAFTTGSDDATCRLFDLRA---DQELLMYSHDNIIC 270 Query: 358 -VYAVDWSPDGEKVVSGGKDRALKLW 432 + +V +S G +++G D +W Sbjct: 271 GITSVAFSRSGRLLLAGYDDFNCNIW 296 Score = 57.8 bits (138), Expect = 2e-08 Identities = 38/141 (26%), Positives = 66/141 (46%), Gaps = 2/141 (1%) Frame = +1 Query: 16 VSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITG 195 VSG+ D ++ LW+ S + GH+ +N V F P+G + S D + +L++ Sbjct: 199 VSGACDASIKLWDVRDS-MCRQTFIGHESDINAVAFFPNGYAFTTGSDDATCRLFDLRAD 257 Query: 196 KFVTAFRGH--VADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAV 369 + + + + + +++S RLLL+G D +WD L GH + V + Sbjct: 258 QELLMYSHDNIICGITSVAFSRSGRLLLAGYDDFNCNIWDAMKGDRAGVLAGHDNRVSCL 317 Query: 370 DWSPDGEKVVSGGKDRALKLW 432 + DG V +G D LK+W Sbjct: 318 GVTDDGMAVATGSWDSFLKIW 338 Score = 53.9 bits (128), Expect = 4e-07 Identities = 25/73 (34%), Positives = 37/73 (50%) Frame = +1 Query: 214 RGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEK 393 RGH+A +Y + W DSRLL+S S+D L +WD +P + V ++P G Sbjct: 51 RGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNF 110 Query: 394 VVSGGKDRALKLW 432 V GG D ++ Sbjct: 111 VACGGLDNICSIY 123 Score = 46.6 bits (109), Expect = 6e-05 Identities = 41/197 (20%), Positives = 69/197 (35%), Gaps = 45/197 (22%) Frame = +1 Query: 61 ISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT---------------- 192 I + + + GH + +++ D + L SAS D + +W+ T Sbjct: 42 IQMRTRRTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMT 101 Query: 193 ------GKFVT-AFRGHVADVYQISWS----------------------ADSRLLLSGSK 285 G FV ++ +Y + D +++ S Sbjct: 102 CAYAPSGNFVACGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFLDDNQIITSSG 161 Query: 286 DSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLWMN*ACL*YHHE 465 D+T +WDI + GH+ +V ++ +PDG VSG D ++KLW Sbjct: 162 DTTCALWDIETGQQTVGFAGHSGDVMSLSLAPDGRTFVSGACDASIKLW----------- 210 Query: 466 CY*DDKCDDQFIEHVDD 516 D C FI H D Sbjct: 211 DVRDSMCRQTFIGHESD 227 Score = 40.4 bits (93), Expect = 0.004 Identities = 27/100 (27%), Positives = 46/100 (46%), Gaps = 3/100 (3%) Frame = +1 Query: 19 SGSDDFTMFLWEPTISKQPKARMTGHQKVV---NHVYFSPDGQWLASASFDKSVKLWNGI 189 +GSDD T L++ + + M H ++ V FS G+ L + D + +W+ + Sbjct: 242 TGSDDATCRLFD--LRADQELLMYSHDNIICGITSVAFSRSGRLLLAGYDDFNCNIWDAM 299 Query: 190 TGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWD 309 G GH V + + D + +GS DS LK+W+ Sbjct: 300 KGDRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN 339
>GBB2_HUMAN (P62879) Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta| subunit 2 (Transducin beta chain 2) (G protein beta 2 subunit) Length = 339 Score = 70.5 bits (171), Expect = 4e-12 Identities = 36/116 (31%), Positives = 61/116 (52%) Frame = +1 Query: 85 MTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSR 264 + GH ++ F D Q + S+ D + LW+ TG+ F GH DV +S + D R Sbjct: 138 LPGHTGYLSCCRFLDDNQIITSSG-DTTCALWDIETGQQTVGFAGHSGDVMSLSLAPDGR 196 Query: 265 LLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 +SG+ D+++K+WD+R +Q GH ++ AV + P+G +G D +L+ Sbjct: 197 TFVSGACDASIKLWDVRDSMCRQTFIGHESDINAVAFFPNGYAFTTGSDDATCRLF 252 Score = 58.2 bits (139), Expect = 2e-08 Identities = 37/146 (25%), Positives = 72/146 (49%), Gaps = 5/146 (3%) Frame = +1 Query: 10 RLVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGI 189 ++++ S D T LW+ +Q GH V + +PDG+ S + D S+KLW+ Sbjct: 155 QIITSSGDTTCALWDIETGQQTVG-FAGHSGDVMSLSLAPDGRTFVSGACDASIKLWDVR 213 Query: 190 TGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADE---- 357 F GH +D+ +++ + +GS D+T +++D+RA Q+L ++ + Sbjct: 214 DSMCRQTFIGHESDINAVAFFPNGYAFTTGSDDATCRLFDLRA---DQELLMYSHDNIIC 270 Query: 358 -VYAVDWSPDGEKVVSGGKDRALKLW 432 + +V +S G +++G D +W Sbjct: 271 GITSVAFSRSGRLLLAGYDDFNCNIW 296 Score = 57.8 bits (138), Expect = 2e-08 Identities = 38/141 (26%), Positives = 66/141 (46%), Gaps = 2/141 (1%) Frame = +1 Query: 16 VSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITG 195 VSG+ D ++ LW+ S + GH+ +N V F P+G + S D + +L++ Sbjct: 199 VSGACDASIKLWDVRDS-MCRQTFIGHESDINAVAFFPNGYAFTTGSDDATCRLFDLRAD 257 Query: 196 KFVTAFRGH--VADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAV 369 + + + + + +++S RLLL+G D +WD L GH + V + Sbjct: 258 QELLMYSHDNIICGITSVAFSRSGRLLLAGYDDFNCNIWDAMKGDRAGVLAGHDNRVSCL 317 Query: 370 DWSPDGEKVVSGGKDRALKLW 432 + DG V +G D LK+W Sbjct: 318 GVTDDGMAVATGSWDSFLKIW 338 Score = 53.9 bits (128), Expect = 4e-07 Identities = 25/73 (34%), Positives = 37/73 (50%) Frame = +1 Query: 214 RGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEK 393 RGH+A +Y + W DSRLL+S S+D L +WD +P + V ++P G Sbjct: 51 RGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNF 110 Query: 394 VVSGGKDRALKLW 432 V GG D ++ Sbjct: 111 VACGGLDNICSIY 123 Score = 46.6 bits (109), Expect = 6e-05 Identities = 41/197 (20%), Positives = 69/197 (35%), Gaps = 45/197 (22%) Frame = +1 Query: 61 ISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT---------------- 192 I + + + GH + +++ D + L SAS D + +W+ T Sbjct: 42 IQMRTRRTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMT 101 Query: 193 ------GKFVT-AFRGHVADVYQISWS----------------------ADSRLLLSGSK 285 G FV ++ +Y + D +++ S Sbjct: 102 CAYAPSGNFVACGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFLDDNQIITSSG 161 Query: 286 DSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLWMN*ACL*YHHE 465 D+T +WDI + GH+ +V ++ +PDG VSG D ++KLW Sbjct: 162 DTTCALWDIETGQQTVGFAGHSGDVMSLSLAPDGRTFVSGACDASIKLW----------- 210 Query: 466 CY*DDKCDDQFIEHVDD 516 D C FI H D Sbjct: 211 DVRDSMCRQTFIGHESD 227 Score = 40.4 bits (93), Expect = 0.004 Identities = 27/100 (27%), Positives = 46/100 (46%), Gaps = 3/100 (3%) Frame = +1 Query: 19 SGSDDFTMFLWEPTISKQPKARMTGHQKVV---NHVYFSPDGQWLASASFDKSVKLWNGI 189 +GSDD T L++ + + M H ++ V FS G+ L + D + +W+ + Sbjct: 242 TGSDDATCRLFD--LRADQELLMYSHDNIICGITSVAFSRSGRLLLAGYDDFNCNIWDAM 299 Query: 190 TGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWD 309 G GH V + + D + +GS DS LK+W+ Sbjct: 300 KGDRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN 339
>GBB2_BOVIN (P11017) Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta| subunit 2 (Transducin beta chain 2) (G protein beta 2 subunit) (Fragment) Length = 326 Score = 70.5 bits (171), Expect = 4e-12 Identities = 36/116 (31%), Positives = 61/116 (52%) Frame = +1 Query: 85 MTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSR 264 + GH ++ F D Q + S+ D + LW+ TG+ F GH DV +S + D R Sbjct: 125 LPGHTGYLSCCRFLDDNQIITSSG-DTTCALWDIETGQQTVGFAGHSGDVMSLSLAPDGR 183 Query: 265 LLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 +SG+ D+++K+WD+R +Q GH ++ AV + P+G +G D +L+ Sbjct: 184 TFVSGACDASIKLWDVRDSMCRQTFIGHESDINAVAFFPNGYAFTTGSDDATCRLF 239 Score = 58.2 bits (139), Expect = 2e-08 Identities = 37/146 (25%), Positives = 72/146 (49%), Gaps = 5/146 (3%) Frame = +1 Query: 10 RLVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGI 189 ++++ S D T LW+ +Q GH V + +PDG+ S + D S+KLW+ Sbjct: 142 QIITSSGDTTCALWDIETGQQTVG-FAGHSGDVMSLSLAPDGRTFVSGACDASIKLWDVR 200 Query: 190 TGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADE---- 357 F GH +D+ +++ + +GS D+T +++D+RA Q+L ++ + Sbjct: 201 DSMCRQTFIGHESDINAVAFFPNGYAFTTGSDDATCRLFDLRA---DQELLMYSHDNIIC 257 Query: 358 -VYAVDWSPDGEKVVSGGKDRALKLW 432 + +V +S G +++G D +W Sbjct: 258 GITSVAFSRSGRLLLAGYDDFNCNIW 283 Score = 57.8 bits (138), Expect = 2e-08 Identities = 38/141 (26%), Positives = 66/141 (46%), Gaps = 2/141 (1%) Frame = +1 Query: 16 VSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITG 195 VSG+ D ++ LW+ S + GH+ +N V F P+G + S D + +L++ Sbjct: 186 VSGACDASIKLWDVRDS-MCRQTFIGHESDINAVAFFPNGYAFTTGSDDATCRLFDLRAD 244 Query: 196 KFVTAFRGH--VADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAV 369 + + + + + +++S RLLL+G D +WD L GH + V + Sbjct: 245 QELLMYSHDNIICGITSVAFSRSGRLLLAGYDDFNCNIWDAMKGDRAGVLAGHDNRVSCL 304 Query: 370 DWSPDGEKVVSGGKDRALKLW 432 + DG V +G D LK+W Sbjct: 305 GVTDDGMAVATGSWDSFLKIW 325 Score = 53.9 bits (128), Expect = 4e-07 Identities = 25/73 (34%), Positives = 37/73 (50%) Frame = +1 Query: 214 RGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEK 393 RGH+A +Y + W DSRLL+S S+D L +WD +P + V ++P G Sbjct: 38 RGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNF 97 Query: 394 VVSGGKDRALKLW 432 V GG D ++ Sbjct: 98 VACGGLDNICSIY 110 Score = 46.6 bits (109), Expect = 6e-05 Identities = 41/197 (20%), Positives = 69/197 (35%), Gaps = 45/197 (22%) Frame = +1 Query: 61 ISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT---------------- 192 I + + + GH + +++ D + L SAS D + +W+ T Sbjct: 29 IQMRTRRTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMT 88 Query: 193 ------GKFVT-AFRGHVADVYQISWS----------------------ADSRLLLSGSK 285 G FV ++ +Y + D +++ S Sbjct: 89 CAYAPSGNFVACGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFLDDNQIITSSG 148 Query: 286 DSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLWMN*ACL*YHHE 465 D+T +WDI + GH+ +V ++ +PDG VSG D ++KLW Sbjct: 149 DTTCALWDIETGQQTVGFAGHSGDVMSLSLAPDGRTFVSGACDASIKLW----------- 197 Query: 466 CY*DDKCDDQFIEHVDD 516 D C FI H D Sbjct: 198 DVRDSMCRQTFIGHESD 214 Score = 40.4 bits (93), Expect = 0.004 Identities = 27/100 (27%), Positives = 46/100 (46%), Gaps = 3/100 (3%) Frame = +1 Query: 19 SGSDDFTMFLWEPTISKQPKARMTGHQKVV---NHVYFSPDGQWLASASFDKSVKLWNGI 189 +GSDD T L++ + + M H ++ V FS G+ L + D + +W+ + Sbjct: 229 TGSDDATCRLFD--LRADQELLMYSHDNIICGITSVAFSRSGRLLLAGYDDFNCNIWDAM 286 Query: 190 TGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWD 309 G GH V + + D + +GS DS LK+W+ Sbjct: 287 KGDRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN 326
>GRWD1_MOUSE (Q810D6) Glutamate-rich WD repeat-containing protein 1 (Protein| A301) Length = 446 Score = 70.1 bits (170), Expect = 5e-12 Identities = 51/158 (32%), Positives = 72/158 (45%), Gaps = 15/158 (9%) Frame = +1 Query: 4 PXRLVSGSDDFTMFLWEPT------ISKQPKARMTGHQKVVNHVYFSP-DGQWLASASFD 162 P RL++G + LW PT + ++P GH + V + +SP + AS S D Sbjct: 227 PGRLLTGDCQKNVHLWTPTEGGSWNVDQRP---FVGHTRSVEDLQWSPTEDTVFASCSAD 283 Query: 163 KSVKLWN--GITGK--FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLK 330 S+++W+ GK +T H DV ISWS LLSG D LKVWD+R K Sbjct: 284 ASIRIWDIRAAPGKACMLTTATAHDGDVNVISWSRREPFLLSGGDDGALKVWDLRQFKSG 343 Query: 331 QDL---PGHADEVYAVDWSP-DGEKVVSGGKDRALKLW 432 + H V +V+W P D + G D + W Sbjct: 344 SPVATFKQHMAPVTSVEWHPQDSGVFAASGADNQITQW 381 Score = 33.9 bits (76), Expect = 0.38 Identities = 27/131 (20%), Positives = 46/131 (35%), Gaps = 52/131 (39%) Frame = +1 Query: 196 KFVTAFRGHVADVYQISWS----------------------------------------- 252 K + +F GH+ + + + WS Sbjct: 205 KPIFSFAGHMGEGFALDWSPRVPGRLLTGDCQKNVHLWTPTEGGSWNVDQRPFVGHTRSV 264 Query: 253 -------ADSRLLLSGSKDSTLKVWDIRARKLKQDL----PGHADEVYAVDWSPDGEKVV 399 + + S S D+++++WDIRA K + H +V + WS ++ Sbjct: 265 EDLQWSPTEDTVFASCSADASIRIWDIRAAPGKACMLTTATAHDGDVNVISWSRREPFLL 324 Query: 400 SGGKDRALKLW 432 SGG D ALK+W Sbjct: 325 SGGDDGALKVW 335
>A16L1_PONPY (Q5RAC9) Autophagy-related protein 16-1 (APG16-like 1)| Length = 607 Score = 70.1 bits (170), Expect = 5e-12 Identities = 38/115 (33%), Positives = 58/115 (50%), Gaps = 2/115 (1%) Frame = +1 Query: 94 HQKVVNHVYFSPDGQWLASASFDKSVKLWN--GITGKFVTAFRGHVADVYQISWSADSRL 267 H VN V FSP + LA+ D+ VKLW G +F + G A + I + + Sbjct: 321 HDGEVNAVQFSPGSRLLATGGMDRRVKLWEVFGEKCEFKGSLSGSNAGITSIEFDSAGSY 380 Query: 268 LLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 LL+ S D ++W + +L+ L GH+ +V + + D ++VSG DR LK W Sbjct: 381 LLAASNDFASRIWTVDDSRLRHTLTGHSGKVLSAKFLLDNARIVSGSHDRTLKHW 435 Score = 53.1 bits (126), Expect = 6e-07 Identities = 37/143 (25%), Positives = 68/143 (47%), Gaps = 3/143 (2%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISK-QPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGI 189 L +G D + LWE K + K ++G + + F G +L +AS D + ++W Sbjct: 337 LATGGMDRRVKLWEVFGEKCEFKGSLSGSNAGITSIEFDSAGSYLLAASNDFASRIWTVD 396 Query: 190 TGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARK-LKQDLPGHA-DEVY 363 + GH V + D+ ++SGS D TLK WD+R++ +K G + +++ Sbjct: 397 DSRLRHTLTGHSGKVLSAKFLLDNARIVSGSHDRTLKHWDLRSKVCIKTVFAGSSCNDIV 456 Query: 364 AVDWSPDGEKVVSGGKDRALKLW 432 + + V+SG D+ ++ W Sbjct: 457 CTE-----QCVMSGHFDKKIRFW 474 Score = 48.1 bits (113), Expect = 2e-05 Identities = 41/145 (28%), Positives = 65/145 (44%), Gaps = 4/145 (2%) Frame = +1 Query: 10 RLVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGI 189 R+VSGS D T+ W+ K G N + + Q + S FDK ++ W+ I Sbjct: 422 RIVSGSHDRTLKHWDLRSKVCIKTVFAGSS--CNDIVCTE--QCVMSGHFDKKIRFWD-I 476 Query: 190 TGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQ--DLPGH--ADE 357 + + + + + + + LLS S+D LKV D+R +KQ PG + Sbjct: 477 RSESIVREMELLGKITALDLNPERTELLSCSRDDLLKVIDLRTNAIKQTFSAPGFKCGSD 536 Query: 358 VYAVDWSPDGEKVVSGGKDRALKLW 432 V +SPDG V +G + +L W Sbjct: 537 WTRVVFSPDGSYVAAGSAEGSLYTW 561 Score = 40.4 bits (93), Expect = 0.004 Identities = 20/76 (26%), Positives = 38/76 (50%), Gaps = 2/76 (2%) Frame = +1 Query: 211 FRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARK--LKQDLPGHADEVYAVDWSPD 384 F H +V + +S SRLL +G D +K+W++ K K L G + ++++ Sbjct: 318 FDAHDGEVNAVQFSPGSRLLATGGMDRRVKLWEVFGEKCEFKGSLSGSNAGITSIEFDSA 377 Query: 385 GEKVVSGGKDRALKLW 432 G +++ D A ++W Sbjct: 378 GSYLLAASNDFASRIW 393 Score = 39.7 bits (91), Expect = 0.007 Identities = 22/70 (31%), Positives = 36/70 (51%), Gaps = 1/70 (1%) Frame = +1 Query: 226 ADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPG-HADEVYAVDWSPDGEKVVS 402 +D ++ +S D + +GS + +L W + K+++ L H+ + AV WSP G VVS Sbjct: 535 SDWTRVVFSPDGSYVAAGSAEGSLYTWSVLTGKVEKVLSKQHSSSINAVAWSPSGLHVVS 594 Query: 403 GGKDRALKLW 432 K LW Sbjct: 595 VDKGCKAVLW 604 Score = 38.9 bits (89), Expect = 0.012 Identities = 19/65 (29%), Positives = 34/65 (52%), Gaps = 1/65 (1%) Frame = +1 Query: 115 VYFSPDGQWLASASFDKSVKLWNGITGKFVTAF-RGHVADVYQISWSADSRLLLSGSKDS 291 V FSPDG ++A+ S + S+ W+ +TGK + H + + ++WS ++S K Sbjct: 540 VVFSPDGSYVAAGSAEGSLYTWSVLTGKVEKVLSKQHSSSINAVAWSPSGLHVVSVDKGC 599 Query: 292 TLKVW 306 +W Sbjct: 600 KAVLW 604
>GBB3_RAT (P52287) Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta| subunit 3 (Transducin beta chain 3) Length = 340 Score = 70.1 bits (170), Expect = 5e-12 Identities = 32/101 (31%), Positives = 58/101 (57%) Frame = +1 Query: 130 DGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWD 309 D + ++S D + LW+ TG+ T F GH D ++ S D +L +SG+ D++ K+WD Sbjct: 153 DDNNIVTSSGDTTCALWDIETGQQKTVFVGHTGDCMSLAVSPDYKLFISGACDASAKLWD 212 Query: 310 IRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 +R +Q GH ++ A+ + P+GE + +G D + +L+ Sbjct: 213 VREGTCRQTFTGHESDINAICFFPNGEAICTGSDDASCRLF 253 Score = 62.8 bits (151), Expect = 8e-10 Identities = 39/141 (27%), Positives = 69/141 (48%), Gaps = 2/141 (1%) Frame = +1 Query: 16 VSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITG 195 +SG+ D + LW+ + TGH+ +N + F P+G+ + + S D S +L++ Sbjct: 200 ISGACDASAKLWDVR-EGTCRQTFTGHESDINAICFFPNGEAICTGSDDASCRLFDLRAD 258 Query: 196 KFVTAFRGH--VADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAV 369 + +TA+ + + +++S RLL +G D VWD + L GH + V + Sbjct: 259 QELTAYSHESIICGITSVAFSLSGRLLFAGYDDFNCNVWDSLKCERVGVLSGHDNRVSCL 318 Query: 370 DWSPDGEKVVSGGKDRALKLW 432 + DG V +G D LK+W Sbjct: 319 GVTADGMAVATGSWDSFLKIW 339 Score = 58.5 bits (140), Expect = 1e-08 Identities = 41/150 (27%), Positives = 71/150 (47%), Gaps = 5/150 (3%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 +V+ S D T LW+ +Q K GH + SPD + S + D S KLW+ Sbjct: 157 IVTSSGDTTCALWDIETGQQ-KTVFVGHTGDCMSLAVSPDYKLFISGACDASAKLWDVRE 215 Query: 193 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADE----- 357 G F GH +D+ I + + + +GS D++ +++D+RA Q+L ++ E Sbjct: 216 GTCRQTFTGHESDINAICFFPNGEAICTGSDDASCRLFDLRA---DQELTAYSHESIICG 272 Query: 358 VYAVDWSPDGEKVVSGGKDRALKLWMN*AC 447 + +V +S G + +G D +W + C Sbjct: 273 ITSVAFSLSGRLLFAGYDDFNCNVWDSLKC 302 Score = 53.9 bits (128), Expect = 4e-07 Identities = 25/73 (34%), Positives = 38/73 (52%) Frame = +1 Query: 214 RGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEK 393 RGH+A +Y + W+ DS+LL+S S+D L VWD +P + V ++P G Sbjct: 52 RGHLAKIYAMHWATDSKLLVSASQDGKLIVWDTYTTNKVHAIPLRSSWVMTCAYAPSGNF 111 Query: 394 VVSGGKDRALKLW 432 V GG D ++ Sbjct: 112 VACGGLDNMCSIY 124 Score = 38.9 bits (89), Expect = 0.012 Identities = 27/102 (26%), Positives = 50/102 (49%), Gaps = 3/102 (2%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVV---NHVYFSPDGQWLASASFDKSVKLWN 183 + +GSDD + L++ ++ A H+ ++ V FS G+ L + D + +W+ Sbjct: 241 ICTGSDDASCRLFDLRADQELTAY--SHESIICGITSVAFSLSGRLLFAGYDDFNCNVWD 298 Query: 184 GITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWD 309 + + V GH V + +AD + +GS DS LK+W+ Sbjct: 299 SLKCERVGVLSGHDNRVSCLGVTADGMAVATGSWDSFLKIWN 340 Score = 38.1 bits (87), Expect = 0.020 Identities = 35/169 (20%), Positives = 64/169 (37%), Gaps = 45/169 (26%) Frame = +1 Query: 61 ISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT---------------- 192 + + + + GH + ++++ D + L SAS D + +W+ T Sbjct: 43 VQMRTRRTLRGHLAKIYAMHWATDSKLLVSASQDGKLIVWDTYTTNKVHAIPLRSSWVMT 102 Query: 193 ------GKFVT--------------AFRGHVADVYQISWSA---------DSRLLLSGSK 285 G FV + G+V ++S D +++ S Sbjct: 103 CAYAPSGNFVACGGLDNMCSIYSLKSREGNVKVSRELSAHTGYLSCCRFLDDNNIVTSSG 162 Query: 286 DSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 D+T +WDI + K GH + ++ SPD + +SG D + KLW Sbjct: 163 DTTCALWDIETGQQKTVFVGHTGDCMSLAVSPDYKLFISGACDASAKLW 211
>GBB3_MOUSE (Q61011) Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta| subunit 3 (Transducin beta chain 3) Length = 340 Score = 70.1 bits (170), Expect = 5e-12 Identities = 32/101 (31%), Positives = 58/101 (57%) Frame = +1 Query: 130 DGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWD 309 D + ++S D + LW+ TG+ T F GH D ++ S D +L +SG+ D++ K+WD Sbjct: 153 DDNNIVTSSGDTTCALWDIETGQQKTVFVGHTGDCMSLAVSPDYKLFISGACDASAKLWD 212 Query: 310 IRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 +R +Q GH ++ A+ + P+GE + +G D + +L+ Sbjct: 213 VREGTCRQTFTGHESDINAICFFPNGEAICTGSDDASCRLF 253 Score = 62.8 bits (151), Expect = 8e-10 Identities = 39/141 (27%), Positives = 69/141 (48%), Gaps = 2/141 (1%) Frame = +1 Query: 16 VSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITG 195 +SG+ D + LW+ + TGH+ +N + F P+G+ + + S D S +L++ Sbjct: 200 ISGACDASAKLWDVR-EGTCRQTFTGHESDINAICFFPNGEAICTGSDDASCRLFDLRAD 258 Query: 196 KFVTAFRGH--VADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAV 369 + +TA+ + + +++S RLL +G D VWD + L GH + V + Sbjct: 259 QELTAYSQESIICGITSVAFSLSGRLLFAGYDDFNCNVWDSLKCERVGILSGHDNRVSCL 318 Query: 370 DWSPDGEKVVSGGKDRALKLW 432 + DG V +G D LK+W Sbjct: 319 GVTADGMAVATGSWDSFLKIW 339 Score = 58.9 bits (141), Expect = 1e-08 Identities = 41/150 (27%), Positives = 71/150 (47%), Gaps = 5/150 (3%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 +V+ S D T LW+ +Q K GH + SPD + S + D S KLW+ Sbjct: 157 IVTSSGDTTCALWDIETGQQ-KTVFVGHTGDCMSLAVSPDYKLFISGACDASAKLWDVRE 215 Query: 193 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADE----- 357 G F GH +D+ I + + + +GS D++ +++D+RA Q+L ++ E Sbjct: 216 GTCRQTFTGHESDINAICFFPNGEAICTGSDDASCRLFDLRA---DQELTAYSQESIICG 272 Query: 358 VYAVDWSPDGEKVVSGGKDRALKLWMN*AC 447 + +V +S G + +G D +W + C Sbjct: 273 ITSVAFSLSGRLLFAGYDDFNCNVWDSLKC 302 Score = 53.9 bits (128), Expect = 4e-07 Identities = 25/73 (34%), Positives = 38/73 (52%) Frame = +1 Query: 214 RGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEK 393 RGH+A +Y + W+ DS+LL+S S+D L VWD +P + V ++P G Sbjct: 52 RGHLAKIYAMHWATDSKLLVSASQDGKLIVWDTYTTNKVHAIPLRSSWVMTCAYAPSGNF 111 Query: 394 VVSGGKDRALKLW 432 V GG D ++ Sbjct: 112 VACGGLDNMCSIY 124 Score = 38.1 bits (87), Expect = 0.020 Identities = 26/128 (20%), Positives = 56/128 (43%), Gaps = 4/128 (3%) Frame = +1 Query: 61 ISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQ 240 + + + + GH + ++++ D + L SAS D + +W+ T V A + V Sbjct: 43 VQMRTRRTLRGHLAKIYAMHWATDSKLLVSASQDGKLIVWDTYTTNKVHAIPLRSSWVMT 102 Query: 241 ISWSADSRLLLSGSKDSTLKVWDIRAR----KLKQDLPGHADEVYAVDWSPDGEKVVSGG 408 +++ + G D+ ++++++R K+ ++L H + + D V S G Sbjct: 103 CAYAPSGNFVACGGLDNMCSIYNLKSREGNVKVSRELSAHTGYLSCCRFLDDNNIVTSSG 162 Query: 409 KDRALKLW 432 D LW Sbjct: 163 -DTTCALW 169 Score = 35.8 bits (81), Expect = 0.10 Identities = 26/104 (25%), Positives = 50/104 (48%), Gaps = 5/104 (4%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKV-----VNHVYFSPDGQWLASASFDKSVKL 177 + +GSDD + L++ ++ +T + + + V FS G+ L + D + + Sbjct: 241 ICTGSDDASCRLFDLRADQE----LTAYSQESIICGITSVAFSLSGRLLFAGYDDFNCNV 296 Query: 178 WNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWD 309 W+ + + V GH V + +AD + +GS DS LK+W+ Sbjct: 297 WDSLKCERVGILSGHDNRVSCLGVTADGMAVATGSWDSFLKIWN 340
>GBB3_CANFA (P79147) Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta| subunit 3 (Transducin beta chain 3) Length = 340 Score = 70.1 bits (170), Expect = 5e-12 Identities = 32/101 (31%), Positives = 58/101 (57%) Frame = +1 Query: 130 DGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWD 309 D + ++S D + LW+ TG+ T F GH D ++ S D +L +SG+ D++ K+WD Sbjct: 153 DDNNIVTSSGDTTCALWDIETGQQKTVFVGHTGDCMSLAVSPDFKLFISGACDASAKLWD 212 Query: 310 IRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 +R +Q GH ++ A+ + P+GE + +G D + +L+ Sbjct: 213 VREGTCRQTFTGHESDINAICFFPNGEAICTGSDDASCRLF 253 Score = 63.2 bits (152), Expect = 6e-10 Identities = 38/141 (26%), Positives = 69/141 (48%), Gaps = 2/141 (1%) Frame = +1 Query: 16 VSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITG 195 +SG+ D + LW+ + TGH+ +N + F P+G+ + + S D S +L++ Sbjct: 200 ISGACDASAKLWDVR-EGTCRQTFTGHESDINAICFFPNGEAICTGSDDASCRLFDLRAD 258 Query: 196 KFVTAFRGH--VADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAV 369 + +TA+ + + +++S RLL +G D +WD + L GH + V + Sbjct: 259 QELTAYSDESIICGITSVAFSLSGRLLFAGYDDFNCNIWDSMKGERVGILSGHDNRVSCL 318 Query: 370 DWSPDGEKVVSGGKDRALKLW 432 + DG V +G D LK+W Sbjct: 319 GVTADGMAVATGSWDSFLKVW 339 Score = 60.8 bits (146), Expect = 3e-09 Identities = 41/145 (28%), Positives = 70/145 (48%), Gaps = 5/145 (3%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 +V+ S D T LW+ +Q K GH + SPD + S + D S KLW+ Sbjct: 157 IVTSSGDTTCALWDIETGQQ-KTVFVGHTGDCMSLAVSPDFKLFISGACDASAKLWDVRE 215 Query: 193 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADE----- 357 G F GH +D+ I + + + +GS D++ +++D+RA Q+L ++DE Sbjct: 216 GTCRQTFTGHESDINAICFFPNGEAICTGSDDASCRLFDLRA---DQELTAYSDESIICG 272 Query: 358 VYAVDWSPDGEKVVSGGKDRALKLW 432 + +V +S G + +G D +W Sbjct: 273 ITSVAFSLSGRLLFAGYDDFNCNIW 297 Score = 53.9 bits (128), Expect = 4e-07 Identities = 25/73 (34%), Positives = 38/73 (52%) Frame = +1 Query: 214 RGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEK 393 RGH+A +Y + W+ DS+LL+S S+D L VWD +P + V ++P G Sbjct: 52 RGHLAKIYAMHWATDSKLLVSASQDGKLIVWDTYTTNKVHAIPLRSSWVMTCAYAPSGNF 111 Query: 394 VVSGGKDRALKLW 432 V GG D ++ Sbjct: 112 VACGGLDNMCSIY 124 Score = 39.3 bits (90), Expect = 0.009 Identities = 22/68 (32%), Positives = 35/68 (51%) Frame = +1 Query: 106 VNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSK 285 + V FS G+ L + D + +W+ + G+ V GH V + +AD + +GS Sbjct: 273 ITSVAFSLSGRLLFAGYDDFNCNIWDSMKGERVGILSGHDNRVSCLGVTADGMAVATGSW 332 Query: 286 DSTLKVWD 309 DS LKVW+ Sbjct: 333 DSFLKVWN 340 Score = 38.1 bits (87), Expect = 0.020 Identities = 35/169 (20%), Positives = 64/169 (37%), Gaps = 45/169 (26%) Frame = +1 Query: 61 ISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT---------------- 192 + + + + GH + ++++ D + L SAS D + +W+ T Sbjct: 43 VQMRTRRTLRGHLAKIYAMHWATDSKLLVSASQDGKLIVWDTYTTNKVHAIPLRSSWVMT 102 Query: 193 ------GKFVT--------------AFRGHVADVYQISWSA---------DSRLLLSGSK 285 G FV + G+V ++S D +++ S Sbjct: 103 CAYAPSGNFVACGGLDNMCSIYSLKSREGNVKVSRELSAHTGYLSCCRFLDDNNIVTSSG 162 Query: 286 DSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 D+T +WDI + K GH + ++ SPD + +SG D + KLW Sbjct: 163 DTTCALWDIETGQQKTVFVGHTGDCMSLAVSPDFKLFISGACDASAKLW 211 Score = 35.8 bits (81), Expect = 0.10 Identities = 17/57 (29%), Positives = 33/57 (57%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWN 183 L +G DDF +W+ ++ + ++GH V+ + + DG +A+ S+D +K+WN Sbjct: 285 LFAGYDDFNCNIWD-SMKGERVGILSGHDNRVSCLGVTADGMAVATGSWDSFLKVWN 340
>RBBP7_PONPY (Q5R654) Histone-binding protein RBBP7 (Retinoblastoma-binding| protein 7) (RBBP-7) Length = 426 Score = 69.7 bits (169), Expect = 6e-12 Identities = 54/154 (35%), Positives = 78/154 (50%), Gaps = 14/154 (9%) Frame = +1 Query: 13 LVSGSDDFTMFLWE----PTISK--QPKARMTGHQKVVNHVYFSPDGQWL-ASASFDKSV 171 L+S SDD T+ LW+ P K KA TGH VV V + + L S + D+ + Sbjct: 192 LLSASDDHTVCLWDINAGPKEGKIVDAKAVFTGHSAVVEDVAWHLLHESLFGSVADDQKL 251 Query: 172 KLWN---GITGKFVTAFRGHVADVYQISWSADSRLLLS-GSKDSTLKVWDIRARKLK-QD 336 +W+ T K H A+V +S++ S +L+ GS D T+ +WD+R KLK Sbjct: 252 MMWDTRSNTTSKPSHLVDAHTAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKLHT 311 Query: 337 LPGHADEVY-AVDWSPDGEKVV-SGGKDRALKLW 432 H DE++ V WSP E ++ S G DR L +W Sbjct: 312 FESHKDEIFQVVHWSPHNETILASSGTDRRLNVW 345
>WSB1_HUMAN (Q9Y6I7) WD repeat and SOCS box-containing protein 1 (WSB-1) (SOCS| box-containing WD protein SWiP-1) Length = 421 Score = 69.7 bits (169), Expect = 6e-12 Identities = 42/142 (29%), Positives = 73/142 (51%), Gaps = 2/142 (1%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQW-LASASFDKSVKLWN-G 186 L +G ++ + +W+ K + H +VV + F+PDG L SAS DK++++W+ Sbjct: 143 LATGLNNGRIKIWDVYTGKL-LLNLVDHTEVVRDLTFAPDGSLILVSASRDKTLRVWDLK 201 Query: 187 ITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYA 366 G + RGH VY ++S DS +L S + +W++ + + L GH +V A Sbjct: 202 DDGNMMKVLRGHQNWVYSCAFSPDSSMLCSVGASKAVFLWNMDKYTMIRKLEGHHHDVVA 261 Query: 367 VDWSPDGEKVVSGGKDRALKLW 432 D+SPDG + + D + +W Sbjct: 262 CDFSPDGALLATASYDTRVYIW 283 Score = 62.8 bits (151), Expect = 8e-10 Identities = 45/153 (29%), Positives = 65/153 (42%), Gaps = 13/153 (8%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 LVS S D T+ +W+ + GHQ V FSPD L S K+V LWN Sbjct: 186 LVSASRDKTLRVWDLKDDGNMMKVLRGHQNWVYSCAFSPDSSMLCSVGASKAVFLWNMDK 245 Query: 193 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQD-----------L 339 + GH DV +S D LL + S D+ + +WD + + Sbjct: 246 YTMIRKLEGHHHDVVACDFSPDGALLATASYDTRVYIWDPHNGDILMEFGHLFPPPTPIF 305 Query: 340 PGHADE--VYAVDWSPDGEKVVSGGKDRALKLW 432 G A++ V +V +S DG V S D+ ++ W Sbjct: 306 AGGANDRWVRSVSFSHDGLHVASLADDKMVRFW 338 Score = 61.2 bits (147), Expect = 2e-09 Identities = 35/106 (33%), Positives = 58/106 (54%), Gaps = 2/106 (1%) Frame = +1 Query: 121 FSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLLL-SGSKDSTL 297 F D LA+ + +K+W+ TGK + H V ++++ D L+L S S+D TL Sbjct: 136 FGQDQLLLATGLNNGRIKIWDVYTGKLLLNLVDHTEVVRDLTFAPDGSLILVSASRDKTL 195 Query: 298 KVWDIR-ARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 +VWD++ + + L GH + VY+ +SPD + S G +A+ LW Sbjct: 196 RVWDLKDDGNMMKVLRGHQNWVYSCAFSPDSSMLCSVGASKAVFLW 241 Score = 45.1 bits (105), Expect = 2e-04 Identities = 20/67 (29%), Positives = 38/67 (56%), Gaps = 1/67 (1%) Frame = +1 Query: 235 YQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKV-VSGGK 411 ++ + D LL +G + +K+WD+ KL +L H + V + ++PDG + VS + Sbjct: 132 HRFRFGQDQLLLATGLNNGRIKIWDVYTGKLLLNLVDHTEVVRDLTFAPDGSLILVSASR 191 Query: 412 DRALKLW 432 D+ L++W Sbjct: 192 DKTLRVW 198
>GBB_ORYSA (Q40687) Guanine nucleotide-binding protein beta subunit| Length = 380 Score = 69.7 bits (169), Expect = 6e-12 Identities = 41/124 (33%), Positives = 74/124 (59%), Gaps = 8/124 (6%) Frame = +1 Query: 85 MTGHQKVVNHVYFSPDGQW-LASASFDKSVKLWNGITGKFVTAF-----RGHVADVYQIS 246 +TGH+ V+ + PD + L ++S D++ LW+ TG+ ++ F GH ADV +S Sbjct: 153 LTGHKGYVSSCQYVPDQETRLITSSGDQTCVLWDVTTGQRISIFGGEFPSGHTADVLSLS 212 Query: 247 W-SADSRLLLSGSKDSTLKVWDIR-ARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRA 420 S++S + +SGS D+T+++WDIR A + + GH ++ +V + PDG++ +G D Sbjct: 213 INSSNSNMFVSGSCDATVRLWDIRIASRAVRTYHGHEGDINSVKFFPDGQRFGTGSDDGT 272 Query: 421 LKLW 432 +L+ Sbjct: 273 CRLF 276 Score = 64.7 bits (156), Expect = 2e-10 Identities = 43/150 (28%), Positives = 70/150 (46%), Gaps = 11/150 (7%) Frame = +1 Query: 16 VSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITG 195 VSGS D T+ LW+ I+ + GH+ +N V F PDGQ + S D + +L++ TG Sbjct: 222 VSGSCDATVRLWDIRIASRAVRTYHGHEGDINSVKFFPDGQRFGTGSDDGTCRLFDVRTG 281 Query: 196 KFVTAFR-------GHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDL----P 342 + + + V I++S RLL +G + VWD ++ +L Sbjct: 282 HQLQVYSREPDRNDNELPTVTSIAFSISGRLLFAGYSNGDCYVWDTLLAEVVLNLGNLQN 341 Query: 343 GHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 H + + S DG + +G D+ LK+W Sbjct: 342 SHEGRISCLGLSSDGSALCTGSWDKNLKIW 371 Score = 48.5 bits (114), Expect = 2e-05 Identities = 28/124 (22%), Positives = 60/124 (48%), Gaps = 8/124 (6%) Frame = +1 Query: 85 MTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSR 264 + GH V + ++P+ W+ SAS D + +WN +T + A + H V +++ + + Sbjct: 62 LQGHSGKVYSLDWTPEKNWIVSASQDGRLIVWNALTSQKTHAIKLHCPWVMTCAFAPNGQ 121 Query: 265 LLLSGSKDSTLKVWDIRAR-------KLKQDLPGHADEVYAVDWSPDGE-KVVSGGKDRA 420 + G DS ++++ ++ + + L GH V + + PD E ++++ D+ Sbjct: 122 SVACGGLDSACSIFNLNSQADRDGNIPVSRILTGHKGYVSSCQYVPDQETRLITSSGDQT 181 Query: 421 LKLW 432 LW Sbjct: 182 CVLW 185
>GBB3_HUMAN (P16520) Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta| subunit 3 (Transducin beta chain 3) Length = 340 Score = 69.3 bits (168), Expect = 8e-12 Identities = 32/101 (31%), Positives = 57/101 (56%) Frame = +1 Query: 130 DGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWD 309 D + ++S D + LW+ TG+ T F GH D ++ S D L +SG+ D++ K+WD Sbjct: 153 DDNNIVTSSGDTTCALWDIETGQQKTVFVGHTGDCMSLAVSPDFNLFISGACDASAKLWD 212 Query: 310 IRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 +R +Q GH ++ A+ + P+GE + +G D + +L+ Sbjct: 213 VREGTCRQTFTGHESDINAICFFPNGEAICTGSDDASCRLF 253 Score = 61.2 bits (147), Expect = 2e-09 Identities = 38/141 (26%), Positives = 67/141 (47%), Gaps = 2/141 (1%) Frame = +1 Query: 16 VSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITG 195 +SG+ D + LW+ + TGH+ +N + F P+G+ + + S D S +L++ Sbjct: 200 ISGACDASAKLWDVR-EGTCRQTFTGHESDINAICFFPNGEAICTGSDDASCRLFDLRAD 258 Query: 196 KFVTAFRGH--VADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAV 369 + + F + + +++S RLL +G D VWD + L GH + V + Sbjct: 259 QELICFSHESIICGITSVAFSLSGRLLFAGYDDFNCNVWDSMKSERVGILSGHDNRVSCL 318 Query: 370 DWSPDGEKVVSGGKDRALKLW 432 + DG V +G D LK+W Sbjct: 319 GVTADGMAVATGSWDSFLKIW 339 Score = 54.3 bits (129), Expect = 3e-07 Identities = 40/145 (27%), Positives = 67/145 (46%), Gaps = 5/145 (3%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 +V+ S D T LW+ +Q K GH + SPD S + D S KLW+ Sbjct: 157 IVTSSGDTTCALWDIETGQQ-KTVFVGHTGDCMSLAVSPDFNLFISGACDASAKLWDVRE 215 Query: 193 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADE----- 357 G F GH +D+ I + + + +GS D++ +++D+RA Q+L + E Sbjct: 216 GTCRQTFTGHESDINAICFFPNGEAICTGSDDASCRLFDLRA---DQELICFSHESIICG 272 Query: 358 VYAVDWSPDGEKVVSGGKDRALKLW 432 + +V +S G + +G D +W Sbjct: 273 ITSVAFSLSGRLLFAGYDDFNCNVW 297 Score = 53.5 bits (127), Expect = 5e-07 Identities = 25/73 (34%), Positives = 38/73 (52%) Frame = +1 Query: 214 RGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEK 393 RGH+A +Y + W+ DS+LL+S S+D L VWD +P + V ++P G Sbjct: 52 RGHLAKIYAMHWATDSKLLVSASQDGKLIVWDSYTTNKVHAIPLRSSWVMTCAYAPSGNF 111 Query: 394 VVSGGKDRALKLW 432 V GG D ++ Sbjct: 112 VACGGLDNMCSIY 124 Score = 38.9 bits (89), Expect = 0.012 Identities = 26/128 (20%), Positives = 56/128 (43%), Gaps = 4/128 (3%) Frame = +1 Query: 61 ISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQ 240 + + + + GH + ++++ D + L SAS D + +W+ T V A + V Sbjct: 43 VQMRTRRTLRGHLAKIYAMHWATDSKLLVSASQDGKLIVWDSYTTNKVHAIPLRSSWVMT 102 Query: 241 ISWSADSRLLLSGSKDSTLKVWDIRAR----KLKQDLPGHADEVYAVDWSPDGEKVVSGG 408 +++ + G D+ ++++++R K+ ++L H + + D V S G Sbjct: 103 CAYAPSGNFVACGGLDNMCSIYNLKSREGNVKVSRELSAHTGYLSCCRFLDDNNIVTSSG 162 Query: 409 KDRALKLW 432 D LW Sbjct: 163 -DTTCALW 169 Score = 38.1 bits (87), Expect = 0.020 Identities = 26/102 (25%), Positives = 49/102 (48%), Gaps = 3/102 (2%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVV---NHVYFSPDGQWLASASFDKSVKLWN 183 + +GSDD + L++ + + H+ ++ V FS G+ L + D + +W+ Sbjct: 241 ICTGSDDASCRLFD--LRADQELICFSHESIICGITSVAFSLSGRLLFAGYDDFNCNVWD 298 Query: 184 GITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWD 309 + + V GH V + +AD + +GS DS LK+W+ Sbjct: 299 SMKSERVGILSGHDNRVSCLGVTADGMAVATGSWDSFLKIWN 340
>COPB2_MOUSE (O55029) Coatomer subunit beta' (Beta'-coat protein) (Beta'-COP)| (p102) Length = 905 Score = 69.3 bits (168), Expect = 8e-12 Identities = 39/143 (27%), Positives = 67/143 (46%), Gaps = 3/143 (2%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSP-DGQWLASASFDKSVKLWNGI 189 +++ SDD + LW+ GH V + +P D ASAS D+++K+W Sbjct: 114 ILTSSDDMLIKLWDWDKKWSCSQVFEGHTHYVMQIVINPKDNNQFASASLDRTIKVWQLG 173 Query: 190 TGKFVTAFRGHVADVYQISW--SADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVY 363 + GH V I + D L+SG+ D +K+WD + + Q L GHA V Sbjct: 174 SSSPNFTLEGHEKGVNCIDYYSGGDKPYLISGADDRLVKIWDYQNKTCVQTLEGHAQNVS 233 Query: 364 AVDWSPDGEKVVSGGKDRALKLW 432 + P+ +++G +D +++W Sbjct: 234 CASFHPELPIIITGSEDGTVRIW 256 Score = 55.8 bits (133), Expect = 9e-08 Identities = 34/122 (27%), Positives = 61/122 (50%), Gaps = 2/122 (1%) Frame = +1 Query: 10 RLVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHV--YFSPDGQWLASASFDKSVKLWN 183 + S S D T+ +W+ S P + GH+K VN + Y D +L S + D+ VK+W+ Sbjct: 157 QFASASLDRTIKVWQLG-SSSPNFTLEGHEKGVNCIDYYSGGDKPYLISGADDRLVKIWD 215 Query: 184 GITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVY 363 V GH +V S+ + ++++GS+D T+++W +L+ L + V+ Sbjct: 216 YQNKTCVQTLEGHAQNVSCASFHPELPIIITGSEDGTVRIWHSSTYRLESTLNYGMERVW 275 Query: 364 AV 369 V Sbjct: 276 CV 277 Score = 43.1 bits (100), Expect = 6e-04 Identities = 25/119 (21%), Positives = 50/119 (42%) Frame = +1 Query: 76 KARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSA 255 K ++T V V P W+ ++ ++ SV +WN T V F V + A Sbjct: 8 KRKLTARSDRVKSVDLHPTEPWMLASLYNGSVCVWNHETQTLVKTFEVCDLPVRAAKFVA 67 Query: 256 DSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 +++G+ D ++V++ + H+D + + P +++ D +KLW Sbjct: 68 RKNWVVTGADDMQIRVFNYNTLERVHMFEAHSDYIRCIAVHPTQPFILTSSDDMLIKLW 126
>COPB2_HUMAN (P35606) Coatomer subunit beta' (Beta'-coat protein) (Beta'-COP)| (p102) Length = 905 Score = 69.3 bits (168), Expect = 8e-12 Identities = 39/143 (27%), Positives = 67/143 (46%), Gaps = 3/143 (2%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSP-DGQWLASASFDKSVKLWNGI 189 +++ SDD + LW+ GH V + +P D ASAS D+++K+W Sbjct: 113 ILTSSDDMLIKLWDWDKKWSCSQVFEGHTHYVMQIVINPKDNNQFASASLDRTIKVWQLG 172 Query: 190 TGKFVTAFRGHVADVYQISW--SADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVY 363 + GH V I + D L+SG+ D +K+WD + + Q L GHA V Sbjct: 173 SSSPNFTLEGHEKGVNCIDYYSGGDKPYLISGADDRLVKIWDYQNKTCVQTLEGHAQNVS 232 Query: 364 AVDWSPDGEKVVSGGKDRALKLW 432 + P+ +++G +D +++W Sbjct: 233 CASFHPELPIIITGSEDGTVRIW 255 Score = 55.8 bits (133), Expect = 9e-08 Identities = 34/122 (27%), Positives = 61/122 (50%), Gaps = 2/122 (1%) Frame = +1 Query: 10 RLVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHV--YFSPDGQWLASASFDKSVKLWN 183 + S S D T+ +W+ S P + GH+K VN + Y D +L S + D+ VK+W+ Sbjct: 156 QFASASLDRTIKVWQLG-SSSPNFTLEGHEKGVNCIDYYSGGDKPYLISGADDRLVKIWD 214 Query: 184 GITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVY 363 V GH +V S+ + ++++GS+D T+++W +L+ L + V+ Sbjct: 215 YQNKTCVQTLEGHAQNVSCASFHPELPIIITGSEDGTVRIWHSSTYRLESTLNYGMERVW 274 Query: 364 AV 369 V Sbjct: 275 CV 276 Score = 43.1 bits (100), Expect = 6e-04 Identities = 25/119 (21%), Positives = 50/119 (42%) Frame = +1 Query: 76 KARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSA 255 K ++T V V P W+ ++ ++ SV +WN T V F V + A Sbjct: 7 KRKLTARSDRVKSVDLHPTEPWMLASLYNGSVCVWNHETQTLVKTFEVCDLPVRAAKFVA 66 Query: 256 DSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 +++G+ D ++V++ + H+D + + P +++ D +KLW Sbjct: 67 RKNWVVTGADDMQIRVFNYNTLERVHMFEAHSDYIRCIAVHPTQPFILTSSDDMLIKLW 125
>COPB2_BOVIN (P35605) Coatomer subunit beta' (Beta'-coat protein) (Beta'-COP)| (p102) Length = 905 Score = 69.3 bits (168), Expect = 8e-12 Identities = 39/143 (27%), Positives = 67/143 (46%), Gaps = 3/143 (2%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSP-DGQWLASASFDKSVKLWNGI 189 +++ SDD + LW+ GH V + +P D ASAS D+++K+W Sbjct: 113 ILTSSDDMLIKLWDWDKKWSCSQVFEGHTHYVMQIVINPKDNNQFASASLDRTIKVWQLG 172 Query: 190 TGKFVTAFRGHVADVYQISW--SADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVY 363 + GH V I + D L+SG+ D +K+WD + + Q L GHA V Sbjct: 173 SSSPNFTLEGHEKGVNCIDYYSGGDKPYLISGADDRLVKIWDYQNKTCVQTLEGHAQNVS 232 Query: 364 AVDWSPDGEKVVSGGKDRALKLW 432 + P+ +++G +D +++W Sbjct: 233 CASFHPELPIIITGSEDGTVRIW 255 Score = 55.8 bits (133), Expect = 9e-08 Identities = 34/122 (27%), Positives = 61/122 (50%), Gaps = 2/122 (1%) Frame = +1 Query: 10 RLVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHV--YFSPDGQWLASASFDKSVKLWN 183 + S S D T+ +W+ S P + GH+K VN + Y D +L S + D+ VK+W+ Sbjct: 156 QFASASLDRTIKVWQLG-SSSPNFTLEGHEKGVNCIDYYSGGDKPYLISGADDRLVKIWD 214 Query: 184 GITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVY 363 V GH +V S+ + ++++GS+D T+++W +L+ L + V+ Sbjct: 215 YQNKTCVQTLEGHAQNVSCASFHPELPIIITGSEDGTVRIWHSSTYRLESTLNYGMERVW 274 Query: 364 AV 369 V Sbjct: 275 CV 276 Score = 43.1 bits (100), Expect = 6e-04 Identities = 25/119 (21%), Positives = 50/119 (42%) Frame = +1 Query: 76 KARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSA 255 K ++T V V P W+ ++ ++ SV +WN T V F V + A Sbjct: 7 KRKLTARSDRVKSVDLHPTEPWMLASLYNGSVCVWNHETQTLVKTFEVCDLPVRAAKFVA 66 Query: 256 DSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 +++G+ D ++V++ + H+D + + P +++ D +KLW Sbjct: 67 RKNWVVTGADDMQIRVFNYNTLERVHMFEAHSDYIRCIAVHPTQPFILTSSDDMLIKLW 125
>GBB_SOLTU (P93563) Guanine nucleotide-binding protein beta subunit| Length = 377 Score = 68.9 bits (167), Expect = 1e-11 Identities = 45/152 (29%), Positives = 69/152 (45%), Gaps = 9/152 (5%) Frame = +1 Query: 4 PXRLVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWN 183 P VSGS D T LW+ ++ + + GH+ VN V F PDG + S D S +L++ Sbjct: 217 PKLFVSGSCDTTARLWDTRVASRAQRTFHGHESDVNTVKFFPDGNRFGTGSDDGSCRLFD 276 Query: 184 GITGKFVTAFR-----GHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDL--- 339 TG + + G + V +++S RLL G + VWD K+ +L Sbjct: 277 IRTGHQLQVYNQPHGDGDIPHVTSMAFSISGRLLFVGYSNGDCYVWDTLLAKVVLNLGSV 336 Query: 340 -PGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 H + + S DG + +G D LK+W Sbjct: 337 QNSHEGRISCLGLSADGSALCTGSWDTNLKIW 368 Score = 65.1 bits (157), Expect = 2e-10 Identities = 43/129 (33%), Positives = 72/129 (55%), Gaps = 9/129 (6%) Frame = +1 Query: 73 PKARM-TGHQKVVNHVYFSPDGQW-LASASFDKSVKLWNGITGKFVTAF-----RGHVAD 231 P +RM +GH+ V+ + PD L ++S D++ LW+ TG + F GH AD Sbjct: 147 PVSRMLSGHKGYVSSCQYVPDEDTHLITSSGDQTCVLWDITTGLRTSVFGGEFQSGHTAD 206 Query: 232 VYQISWSADS-RLLLSGSKDSTLKVWDIR-ARKLKQDLPGHADEVYAVDWSPDGEKVVSG 405 V +S S+ + +L +SGS D+T ++WD R A + ++ GH +V V + PDG + +G Sbjct: 207 VLSVSISSSNPKLFVSGSCDTTARLWDTRVASRAQRTFHGHESDVNTVKFFPDGNRFGTG 266 Query: 406 GKDRALKLW 432 D + +L+ Sbjct: 267 SDDGSCRLF 275 Score = 42.4 bits (98), Expect = 0.001 Identities = 20/73 (27%), Positives = 34/73 (46%) Frame = +1 Query: 214 RGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEK 393 +GH VY + W+ + ++S S+D L VW+ + + V +SP G+ Sbjct: 62 QGHTGKVYSLDWTPEKNRIVSASQDGRLIVWNALTSQKTHAIKLPCAWVMTCAFSPSGQS 121 Query: 394 VVSGGKDRALKLW 432 V GG D A ++ Sbjct: 122 VACGGLDSACSIF 134 Score = 38.9 bits (89), Expect = 0.012 Identities = 27/124 (21%), Positives = 56/124 (45%), Gaps = 8/124 (6%) Frame = +1 Query: 85 MTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSR 264 + GH V + ++P+ + SAS D + +WN +T + A + A V ++S + Sbjct: 61 LQGHTGKVYSLDWTPEKNRIVSASQDGRLIVWNALTSQKTHAIKLPCAWVMTCAFSPSGQ 120 Query: 265 LLLSGSKDSTLKVWDIRA-------RKLKQDLPGHADEVYAVDWSPDGE-KVVSGGKDRA 420 + G DS ++++ + + + L GH V + + PD + +++ D+ Sbjct: 121 SVACGGLDSACSIFNLNSPIDKDGIHPVSRMLSGHKGYVSSCQYVPDEDTHLITSSGDQT 180 Query: 421 LKLW 432 LW Sbjct: 181 CVLW 184
>POP2_SCHPO (O14170) WD-repeat protein pop2 (Proteolysis factor sud1)| Length = 703 Score = 68.9 bits (167), Expect = 1e-11 Identities = 43/140 (30%), Positives = 70/140 (50%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 LVSGS D ++ +W + + + GH + V + P+ S S DKS+++W+ T Sbjct: 520 LVSGSYDSSIRIWRVSTG-ECLYHLRGHSLRIYSVLYEPERNICISGSMDKSIRVWDLST 578 Query: 193 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVD 372 G GH D + + L+SGS DST+++WD+ K LP ++ Y Sbjct: 579 GTCKYVLEGH--DAFVTLLNVFQNRLISGSADSTIRIWDLNTGKPLMVLPSNSG--YISS 634 Query: 373 WSPDGEKVVSGGKDRALKLW 432 + D K++S G D ++KLW Sbjct: 635 FVSDEHKIIS-GNDGSVKLW 653 Score = 67.4 bits (163), Expect = 3e-11 Identities = 40/159 (25%), Positives = 72/159 (45%), Gaps = 19/159 (11%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKA-------------------RMTGHQKVVNHVYFSPDG 135 +VSGS D T+ +W+ + P + GH V + S G Sbjct: 460 IVSGSRDHTLRVWKLPKNTDPPYLPDNTNSIDRWEKNPYFVHTLIGHTDSVRTI--SGYG 517 Query: 136 QWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIR 315 L S S+D S+++W TG+ + RGH +Y + + + + +SGS D +++VWD+ Sbjct: 518 DILVSGSYDSSIRIWRVSTGECLYHLRGHSLRIYSVLYEPERNICISGSMDKSIRVWDLS 577 Query: 316 ARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 K L GH + + + +++SG D +++W Sbjct: 578 TGTCKYVLEGH--DAFVTLLNVFQNRLISGSADSTIRIW 614 Score = 53.1 bits (126), Expect = 6e-07 Identities = 43/153 (28%), Positives = 67/153 (43%), Gaps = 34/153 (22%) Frame = +1 Query: 76 KARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSA 255 +AR+ GH++ V V + L S S DK+V++WN K FRGH++ + + Sbjct: 384 EARLEGHKEGVWAVKIHENT--LVSGSIDKTVRVWNIEKAKCTHIFRGHISIIRCLEILV 441 Query: 256 DSRL--------------LLSGSKDSTLKVWDIRARKLKQDLP----------------- 342 SRL ++SGS+D TL+VW + LP Sbjct: 442 PSRLIRHGVEIVEPDQPYIVSGSRDHTLRVWKLPKNTDPPYLPDNTNSIDRWEKNPYFVH 501 Query: 343 ---GHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 GH D V + S G+ +VSG D ++++W Sbjct: 502 TLIGHTDSVRTI--SGYGDILVSGSYDSSIRIW 532 Score = 32.3 bits (72), Expect = 1.1 Identities = 23/82 (28%), Positives = 40/82 (48%) Frame = +1 Query: 10 RLVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGI 189 RL+SGS D T+ +W+ K P + + ++ F D + S + D SVKLW+ Sbjct: 601 RLISGSADSTIRIWDLNTGK-PLMVLPSNSGYISS--FVSDEHKIISGN-DGSVKLWDVR 656 Query: 190 TGKFVTAFRGHVADVYQISWSA 255 TGK + + ++ + + A Sbjct: 657 TGKLLRFLLTDLTKIWHVDFDA 678
>COPA_YEAST (P53622) Coatomer subunit alpha (Alpha-coat protein) (Alpha-COP)| Length = 1201 Score = 68.9 bits (167), Expect = 1e-11 Identities = 45/169 (26%), Positives = 70/169 (41%), Gaps = 30/169 (17%) Frame = +1 Query: 16 VSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITG 195 VS DD+T+ +W +K +TGH V V+F + W+ SAS D+++++WN Sbjct: 69 VSAGDDYTIKVWSLDTNKCLYT-LTGHLDYVRTVFFHRELPWIISASDDQTIRIWNWQNR 127 Query: 196 KFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLP----------- 342 K + GH V + L++S S D T+++WDI + + P Sbjct: 128 KEIACLTGHNHFVMCAQFHPTDDLIVSASLDETIRIWDISGLRKRHSAPGTSSFEEQMSA 187 Query: 343 -------------------GHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 GH V + P +VSG DR +KLW Sbjct: 188 QQNLLDGSLGDCVVKFILEGHTRGVNWASFHPTLPLIVSGSDDRQVKLW 236 Score = 62.0 bits (149), Expect = 1e-09 Identities = 46/172 (26%), Positives = 75/172 (43%), Gaps = 32/172 (18%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWN--- 183 ++S SDD T+ +W K+ A +TGH V F P + SAS D+++++W+ Sbjct: 110 IISASDDQTIRIWNWQNRKEI-ACLTGHNHFVMCAQFHPTDDLIVSASLDETIRIWDISG 168 Query: 184 -------------------------GITGKFVTAF--RGHVADVYQISWSADSRLLLSGS 282 G G V F GH V S+ L++SGS Sbjct: 169 LRKRHSAPGTSSFEEQMSAQQNLLDGSLGDCVVKFILEGHTRGVNWASFHPTLPLIVSGS 228 Query: 283 KDSTLKVWDIRARKLKQ--DLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 D +K+W + A K + GH + V +V + P ++S G+D+ L++W Sbjct: 229 DDRQVKLWRMSATKAWEVDTCRGHTNNVDSVIFHPHQNLIISVGEDKTLRVW 280 Score = 58.2 bits (139), Expect = 2e-08 Identities = 31/117 (26%), Positives = 55/117 (47%) Frame = +1 Query: 82 RMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADS 261 R H+ V + F P SA D ++K+W+ T K + GH+ V + + + Sbjct: 48 RFEDHEGPVRGLDFHPTQPIFVSAGDDYTIKVWSLDTNKCLYTLTGHLDYVRTVFFHREL 107 Query: 262 RLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 ++S S D T+++W+ + RK L GH V + P + +VS D +++W Sbjct: 108 PWIISASDDQTIRIWNWQNRKEIACLTGHNHFVMCAQFHPTDDLIVSASLDETIRIW 164 Score = 57.4 bits (137), Expect = 3e-08 Identities = 27/106 (25%), Positives = 48/106 (45%) Frame = +1 Query: 115 VYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDST 294 + F P W+ A F +++LW+ G + F H V + + + +S D T Sbjct: 17 IAFHPSRPWVLVALFSSTIQLWDYRMGTLLHRFEDHEGPVRGLDFHPTQPIFVSAGDDYT 76 Query: 295 LKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 +KVW + K L GH D V V + + ++S D+ +++W Sbjct: 77 IKVWSLDTNKCLYTLTGHLDYVRTVFFHRELPWIISASDDQTIRIW 122 Score = 49.3 bits (116), Expect = 9e-06 Identities = 28/81 (34%), Positives = 40/81 (49%), Gaps = 2/81 (2%) Frame = +1 Query: 85 MTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKF--VTAFRGHVADVYQISWSAD 258 + GH + VN F P + S S D+ VKLW K V RGH +V + + Sbjct: 205 LEGHTRGVNWASFHPTLPLIVSGSDDRQVKLWRMSATKAWEVDTCRGHTNNVDSVIFHPH 264 Query: 259 SRLLLSGSKDSTLKVWDIRAR 321 L++S +D TL+VWD+ R Sbjct: 265 QNLIISVGEDKTLRVWDLDKR 285
>HIRA_MOUSE (Q61666) HIRA protein (TUP1-like enhancer of split protein 1)| Length = 1015 Score = 68.6 bits (166), Expect = 1e-11 Identities = 42/137 (30%), Positives = 65/137 (47%), Gaps = 20/137 (14%) Frame = +1 Query: 82 RMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWN-----------GITGKF--------V 204 +M H VN V +S G +LAS DK + +W G +GK V Sbjct: 65 QMDNHLACVNCVRWSNSGMYLASGGDDKLIMVWKRATYIGPSTVFGSSGKLANVEQWRCV 124 Query: 205 TAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWD-IRARKLKQDLPGHADEVYAVDWSP 381 + R H DV ++WS L S S D+T+ +W+ ++ ++ L GH+ V + W P Sbjct: 125 SILRSHSGDVMDVAWSPHDAWLASCSVDNTVVIWNAVKFPEILATLRGHSGLVKGLTWDP 184 Query: 382 DGEKVVSGGKDRALKLW 432 G+ + S DR+LK+W Sbjct: 185 VGKYIASQADDRSLKVW 201 Score = 57.0 bits (136), Expect = 4e-08 Identities = 42/168 (25%), Positives = 71/168 (42%), Gaps = 27/168 (16%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 L S S D T+ +W + A + GH +V + + P G+++AS + D+S+K+W + Sbjct: 146 LASCSVDNTVVIWNAVKFPEILATLRGHSGLVKGLTWDPVGKYIASQADDRSLKVWRTLD 205 Query: 193 GKFVTAFR------GHVADVYQISWSADSRLLLS----GSKDSTLKVWDIRARKLKQDLP 342 + T+ G V ++SWS D L+S + T ++ + K D Sbjct: 206 WQLETSITKPCDECGGTTHVLRLSWSPDGHYLVSAHAMNNSGPTAQIIEREGWKTNMDFV 265 Query: 343 GHADEVYAVDWSPDGEK-----------------VVSGGKDRALKLWM 435 GH V V ++P K G KDR+L +W+ Sbjct: 266 GHRKAVTVVKFNPKIFKKKQKNGSSTKPSCPYCCCAVGSKDRSLSVWL 313
>PRP17_YEAST (P40968) Pre-mRNA-splicing factor PRP17 (Cell division control| protein 40) Length = 455 Score = 68.6 bits (166), Expect = 1e-11 Identities = 40/145 (27%), Positives = 70/145 (48%), Gaps = 3/145 (2%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 ++SG +D T+ +W+ + GH K + + F+ D Q S+SFD+SVK+W+ T Sbjct: 178 ILSGGNDHTIKIWDFYHDYECLRDFQGHNKPIKALRFTEDCQSFLSSSFDRSVKIWDTET 237 Query: 193 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARK---LKQDLPGHADEVY 363 GK T + S + + G +S + +D R + L Q H + Sbjct: 238 GKVKTRLHLNSTPADVESRPTNPHEFIVGLSNSKILHYDDRVSENQGLVQTYDHHLSSIL 297 Query: 364 AVDWSPDGEKVVSGGKDRALKLWMN 438 A+ + PDG K +S +D+ +++W N Sbjct: 298 ALKYFPDGSKFISSSEDKTVRIWEN 322 Score = 44.7 bits (104), Expect = 2e-04 Identities = 38/142 (26%), Positives = 64/142 (45%), Gaps = 9/142 (6%) Frame = +1 Query: 10 RLVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGI 189 + +S S+D T+ +WE I+ K Q + + P + + S D + ++ + Sbjct: 307 KFISSSEDKTVRIWENQINVPIKQISDTAQHSMPFLNVHPSQNYFCAQSMDNRIYSFS-L 365 Query: 190 TGKF----VTAFRGHVADVYQIS--WSADSRLLLSGSKDSTLKVWDIRARKLKQD--LPG 345 K+ F+GH + Y IS +S D R + SG S L WD +L + +PG Sbjct: 366 KPKYKRHPKKIFKGHSSAGYGISLAFSGDGRYICSGDSKSRLFTWDWNTSRLLNNIKIPG 425 Query: 346 HADEVYAVDWSP-DGEKVVSGG 408 + + VDW P + KV+ G Sbjct: 426 N-KPITQVDWHPQETSKVICSG 446 Score = 42.0 bits (97), Expect = 0.001 Identities = 19/57 (33%), Positives = 33/57 (57%), Gaps = 1/57 (1%) Frame = +1 Query: 265 LLLSGSKDSTLKVWDI-RARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 L+LSG D T+K+WD + +D GH + A+ ++ D + +S DR++K+W Sbjct: 177 LILSGGNDHTIKIWDFYHDYECLRDFQGHNKPIKALRFTEDCQSFLSSSFDRSVKIW 233 Score = 32.0 bits (71), Expect = 1.5 Identities = 13/39 (33%), Positives = 24/39 (61%), Gaps = 1/39 (2%) Frame = +1 Query: 319 RKLKQDLPGHADEVYAVDWSPD-GEKVVSGGKDRALKLW 432 +K+ ++ PGH + A+ + P G ++SGG D +K+W Sbjct: 152 KKVIRNYPGHPEGTTALKFLPKTGHLILSGGNDHTIKIW 190
>HIRA_HUMAN (P54198) HIRA protein (TUP1-like enhancer of split protein 1)| Length = 1017 Score = 68.6 bits (166), Expect = 1e-11 Identities = 42/137 (30%), Positives = 65/137 (47%), Gaps = 20/137 (14%) Frame = +1 Query: 82 RMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWN-----------GITGKF--------V 204 +M H VN V +S G +LAS DK + +W G +GK V Sbjct: 65 QMDNHLACVNCVRWSNSGMYLASGGDDKLIMVWKRATYIGPSTVFGSSGKLANVEQWRCV 124 Query: 205 TAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWD-IRARKLKQDLPGHADEVYAVDWSP 381 + R H DV ++WS L S S D+T+ +W+ ++ ++ L GH+ V + W P Sbjct: 125 SILRNHSGDVMDVAWSPHDAWLASCSVDNTVVIWNAVKFPEILATLRGHSGLVKGLTWDP 184 Query: 382 DGEKVVSGGKDRALKLW 432 G+ + S DR+LK+W Sbjct: 185 VGKYIASQADDRSLKVW 201 Score = 57.0 bits (136), Expect = 4e-08 Identities = 42/168 (25%), Positives = 71/168 (42%), Gaps = 27/168 (16%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 L S S D T+ +W + A + GH +V + + P G+++AS + D+S+K+W + Sbjct: 146 LASCSVDNTVVIWNAVKFPEILATLRGHSGLVKGLTWDPVGKYIASQADDRSLKVWRTLD 205 Query: 193 GKFVTAFR------GHVADVYQISWSADSRLLLS----GSKDSTLKVWDIRARKLKQDLP 342 + T+ G V ++SWS D L+S + T ++ + K D Sbjct: 206 WQLETSITKPFDECGGTTHVLRLSWSPDGHYLVSAHAMNNSGPTAQIIEREGWKTNMDFV 265 Query: 343 GHADEVYAVDWSPDGEK-----------------VVSGGKDRALKLWM 435 GH V V ++P K G KDR+L +W+ Sbjct: 266 GHRKAVTVVKFNPKIFKKKQKNGSSAKPSCPYCCCAVGSKDRSLSVWL 313
>PRP17_MOUSE (Q9DC48) Pre-mRNA-splicing factor PRP17 (Cell division cycle 40| homolog) Length = 579 Score = 68.2 bits (165), Expect = 2e-11 Identities = 39/143 (27%), Positives = 71/143 (49%), Gaps = 3/143 (2%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 L+S S D + LWE ++ GH K V + F+ G SA++D+ +KLW+ T Sbjct: 304 LLSCSMDCKIKLWEVYGDRRCLRTFIGHSKAVRDICFNTAGTQFLSAAYDRYLKLWDTET 363 Query: 193 GKFVTAFRGHVADVYQISWSAD---SRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVY 363 G+ ++ F Y + ++ D L ++G D + WDIR+ ++ Q+ H V Sbjct: 364 GQCISRFTNRKVP-YCVKFNPDEDKQNLFVAGMSDKKIVQWDIRSGEIVQEYDRHLGAVN 422 Query: 364 AVDWSPDGEKVVSGGKDRALKLW 432 + + + + VS D++L++W Sbjct: 423 TIVFVDENRRFVSTSDDKSLRVW 445 Score = 66.2 bits (160), Expect = 7e-11 Identities = 45/148 (30%), Positives = 68/148 (45%), Gaps = 7/148 (4%) Frame = +1 Query: 10 RLVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGI 189 R VS SDD ++ +WE I K + V SP+G+WLA S D + ++ G Sbjct: 432 RFVSTSDDKSLRVWEWDIPVDFKYIAEPSMHSMPAVTLSPNGKWLACQSMDNQILIF-GA 490 Query: 190 TGKF----VTAFRGHVADVY--QISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHA 351 +F F+GH+ Y Q+ +S D ++SG + L +WD + KL H Sbjct: 491 QNRFRLNKKKIFKGHMVAGYACQVDFSPDMSYVISGDGNGKLNIWDWKTTKLYSRFKAHD 550 Query: 352 DEVYAVDWSP-DGEKVVSGGKDRALKLW 432 W P + KV++ G D +KLW Sbjct: 551 KVCIGAVWHPHETSKVITCGWDGLIKLW 578 Score = 40.4 bits (93), Expect = 0.004 Identities = 29/91 (31%), Positives = 48/91 (52%), Gaps = 1/91 (1%) Frame = +1 Query: 163 KSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRA-RKLKQDL 339 K + +W+G T K V+A R ++ +S LLLS S D +K+W++ R+ + Sbjct: 279 KQIHVWSGHT-KGVSAVR-----LFPLS----GHLLLSCSMDCKIKLWEVYGDRRCLRTF 328 Query: 340 PGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 GH+ V + ++ G + +S DR LKLW Sbjct: 329 IGHSKAVRDICFNTAGTQFLSAAYDRYLKLW 359
>PRP17_HUMAN (O60508) Pre-mRNA-splicing factor PRP17 (hPRP17) (Cell division| cycle 40 homolog) (EH-binding protein 3) (Ehb3) Length = 579 Score = 68.2 bits (165), Expect = 2e-11 Identities = 39/143 (27%), Positives = 71/143 (49%), Gaps = 3/143 (2%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 L+S S D + LWE ++ GH K V + F+ G SA++D+ +KLW+ T Sbjct: 304 LLSCSMDCKIKLWEVYGERRCLRTFIGHSKAVRDICFNTAGTQFLSAAYDRYLKLWDTET 363 Query: 193 GKFVTAFRGHVADVYQISWSAD---SRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVY 363 G+ ++ F Y + ++ D L ++G D + WDIR+ ++ Q+ H V Sbjct: 364 GQCISRFTNRKVP-YCVKFNPDEDKQNLFVAGMSDKKIVQWDIRSGEIVQEYDRHLGAVN 422 Query: 364 AVDWSPDGEKVVSGGKDRALKLW 432 + + + + VS D++L++W Sbjct: 423 TIVFVDENRRFVSTSDDKSLRVW 445 Score = 66.2 bits (160), Expect = 7e-11 Identities = 45/148 (30%), Positives = 68/148 (45%), Gaps = 7/148 (4%) Frame = +1 Query: 10 RLVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGI 189 R VS SDD ++ +WE I K + V SP+G+WLA S D + ++ G Sbjct: 432 RFVSTSDDKSLRVWEWDIPVDFKYIAEPSMHSMPAVTLSPNGKWLACQSMDNQILIF-GA 490 Query: 190 TGKF----VTAFRGHVADVY--QISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHA 351 +F F+GH+ Y Q+ +S D ++SG + L +WD + KL H Sbjct: 491 QNRFRLNKKKIFKGHMVAGYACQVDFSPDMSYVISGDGNGKLNIWDWKTTKLYSRFKAHD 550 Query: 352 DEVYAVDWSP-DGEKVVSGGKDRALKLW 432 W P + KV++ G D +KLW Sbjct: 551 KVCIGAVWHPHETSKVITCGWDGLIKLW 578 Score = 40.4 bits (93), Expect = 0.004 Identities = 29/91 (31%), Positives = 48/91 (52%), Gaps = 1/91 (1%) Frame = +1 Query: 163 KSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRA-RKLKQDL 339 K + +W+G T K V+A R ++ +S LLLS S D +K+W++ R+ + Sbjct: 279 KQIHVWSGHT-KGVSAVR-----LFPLS----GHLLLSCSMDCKIKLWEVYGERRCLRTF 328 Query: 340 PGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 GH+ V + ++ G + +S DR LKLW Sbjct: 329 IGHSKAVRDICFNTAGTQFLSAAYDRYLKLW 359
>GBB3_TOBAC (Q40507) Guanine nucleotide-binding protein beta subunit| Length = 375 Score = 68.2 bits (165), Expect = 2e-11 Identities = 45/152 (29%), Positives = 70/152 (46%), Gaps = 9/152 (5%) Frame = +1 Query: 4 PXRLVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWN 183 P VSGS D T LW+ ++ + + GH+ VN V F PDG + S D + +L++ Sbjct: 217 PRLFVSGSCDTTARLWDNRVASRAQRTFYGHEGDVNTVKFFPDGNRFGTGSEDGTCRLFD 276 Query: 184 GITGKFVTAF-----RGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPG- 345 TG + + G + V +++S RLL G + VWD K+ +L G Sbjct: 277 IRTGHQLQVYYQPHGDGDIPHVTSMAFSISGRLLFVGYSNGDCYVWDTLLAKVVLNLGGV 336 Query: 346 ---HADEVYAVDWSPDGEKVVSGGKDRALKLW 432 H + + S DG + +G D LK+W Sbjct: 337 QNSHEGRISCLGLSADGSALCTGSWDTNLKIW 368 Score = 65.1 bits (157), Expect = 2e-10 Identities = 44/129 (34%), Positives = 72/129 (55%), Gaps = 9/129 (6%) Frame = +1 Query: 73 PKARM-TGHQKVVNHVYFSPDGQW-LASASFDKSVKLWNGITGKFVTAF-----RGHVAD 231 P +RM +GH+ V+ + PD L ++S D++ LW+ TG + F GH AD Sbjct: 147 PVSRMLSGHKGYVSSCQYVPDEDTHLITSSGDQTCVLWDITTGLRTSVFGGEFQSGHTAD 206 Query: 232 VYQISWSADS-RLLLSGSKDSTLKVWDIR-ARKLKQDLPGHADEVYAVDWSPDGEKVVSG 405 V +S S+ + RL +SGS D+T ++WD R A + ++ GH +V V + PDG + +G Sbjct: 207 VQSVSISSSNPRLFVSGSCDTTARLWDNRVASRAQRTFYGHEGDVNTVKFFPDGNRFGTG 266 Query: 406 GKDRALKLW 432 +D +L+ Sbjct: 267 SEDGTCRLF 275 Score = 39.3 bits (90), Expect = 0.009 Identities = 27/124 (21%), Positives = 56/124 (45%), Gaps = 8/124 (6%) Frame = +1 Query: 85 MTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSR 264 + GH V + ++P+ + SAS D + +WN +T + A + A V ++S + Sbjct: 61 LQGHTGKVYSLDWTPEKNRIVSASQDGRLIVWNALTSQKTHAIKLPCAWVMTCAFSPSGQ 120 Query: 265 LLLSGSKDSTLKVWDIRA-------RKLKQDLPGHADEVYAVDWSPDGE-KVVSGGKDRA 420 + G DS ++++ + + + L GH V + + PD + +++ D+ Sbjct: 121 SVACGGLDSVCSIYNLNSPIDKDGNHPVSRMLSGHKGYVSSCQYVPDEDTHLITSSGDQT 180 Query: 421 LKLW 432 LW Sbjct: 181 CVLW 184
>FZR_MOUSE (Q9R1K5) Fizzy-related protein homolog (Fzr) (Cdh1/Hct1 homolog)| Length = 493 Score = 67.8 bits (164), Expect = 2e-11 Identities = 42/134 (31%), Positives = 67/134 (50%), Gaps = 3/134 (2%) Frame = +1 Query: 40 MFLWEPTISKQPK-ARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFR 216 ++LW S+ + ++ V V +S G +A + V++W+ GK ++ Sbjct: 209 VYLWSACTSQVTRLCDLSVEGDSVTSVGWSERGNLVAVGTHKGFVQIWDAAAGKKLSMLE 268 Query: 217 GHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQD--LPGHADEVYAVDWSPDGE 390 GH A V ++W+AD L SGS+D + DIR L+ + L GH EV + WS D + Sbjct: 269 GHTARVGALAWNADQ--LSSGSRDRMILQRDIRTPPLQSERRLQGHRQEVCGLKWSTDHQ 326 Query: 391 KVVSGGKDRALKLW 432 + SGG D L +W Sbjct: 327 LLASGGNDNKLLVW 340 Score = 61.2 bits (147), Expect = 2e-09 Identities = 40/145 (27%), Positives = 69/145 (47%), Gaps = 5/145 (3%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASA---SFDKSVKLWN 183 L SG +D + +W + S P + T H V + +SP L ++ + D+ ++ WN Sbjct: 328 LASGGNDNKLLVWNHS-SLSPVQQYTEHLAAVKAIAWSPHQHGLLASGGGTADRCIRFWN 386 Query: 184 GITGKFVTAFRGHVADVYQISWSADSRLLLS--GSKDSTLKVWDIRARKLKQDLPGHADE 357 +TG+ + + V ++WS + L+S G + + VW + L GH+ Sbjct: 387 TLTGQPLQCIDTG-SQVCNLAWSKHANELVSTHGYSQNQILVWKYPSLTQVAKLTGHSYR 445 Query: 358 VYAVDWSPDGEKVVSGGKDRALKLW 432 V + SPDGE +V+G D L+ W Sbjct: 446 VLYLAMSPDGEAIVTGAGDETLRFW 470 Score = 50.4 bits (119), Expect = 4e-06 Identities = 37/134 (27%), Positives = 62/134 (46%), Gaps = 5/134 (3%) Frame = +1 Query: 46 LWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFR--G 219 +W+ K+ + + GH V + ++ D L+S S D+ + + T + R G Sbjct: 255 IWDAAAGKK-LSMLEGHTARVGALAWNADQ--LSSGSRDRMILQRDIRTPPLQSERRLQG 311 Query: 220 HVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVV 399 H +V + WS D +LL SG D+ L VW+ + Q H V A+ WSP ++ Sbjct: 312 HRQEVCGLKWSTDHQLLASGGNDNKLLVWNHSSLSPVQQYTEHLAAVKAIAWSPHQHGLL 371 Query: 400 SGG---KDRALKLW 432 + G DR ++ W Sbjct: 372 ASGGGTADRCIRFW 385 Score = 39.7 bits (91), Expect = 0.007 Identities = 26/94 (27%), Positives = 40/94 (42%), Gaps = 2/94 (2%) Frame = +1 Query: 148 SASFDKSVKLWNGITGKFVTAFRGHVA--DVYQISWSADSRLLLSGSKDSTLKVWDIRAR 321 S V LW+ T + V V + WS L+ G+ +++WD A Sbjct: 202 SVGLGTCVYLWSACTSQVTRLCDLSVEGDSVTSVGWSERGNLVAVGTHKGFVQIWDAAAG 261 Query: 322 KLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRAL 423 K L GH V A+ W+ D ++ SG +DR + Sbjct: 262 KKLSMLEGHTARVGALAWNAD--QLSSGSRDRMI 293 Score = 33.5 bits (75), Expect = 0.50 Identities = 12/35 (34%), Positives = 24/35 (68%) Frame = +1 Query: 79 ARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWN 183 A++TGH V ++ SPDG+ + + + D++++ WN Sbjct: 437 AKLTGHSYRVLYLAMSPDGEAIVTGAGDETLRFWN 471
>LIN53_CAEEL (P90916) Probable histone-binding protein lin-53 (Abnormal cell| lineage protein 53) Length = 417 Score = 67.4 bits (163), Expect = 3e-11 Identities = 46/151 (30%), Positives = 76/151 (50%), Gaps = 11/151 (7%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISK------QPKARMTGHQKVVNHV--YFSPDGQWLASASFDKS 168 ++S SDD T+ W+ ++ Q K GH+ VV V + DG + S DK Sbjct: 188 ILSASDDQTVCHWDINANQNVAGELQAKDVFKGHESVVEDVAWHVLHDGVF-GSVGDDKK 246 Query: 169 VKLWNGITGKFVTAFRGHVADVYQISWSADSRLLLS-GSKDSTLKVWDIRARKLK-QDLP 342 + +W+ T H A+V ++++ S +L+ GS D T+ +WD+R ++K Sbjct: 247 LLIWDVRTSTPGHCIDAHSAEVNCLAFNPYSEFILATGSADKTVALWDLRNLRMKLHSFE 306 Query: 343 GHADEVYAVDWSPDGEKVV-SGGKDRALKLW 432 H DE++ V WSP E ++ S G D+ L +W Sbjct: 307 SHRDEIFQVQWSPHNETILASSGTDKRLHVW 337 Score = 39.3 bits (90), Expect = 0.009 Identities = 27/82 (32%), Positives = 38/82 (46%), Gaps = 9/82 (10%) Frame = +1 Query: 214 RGHVADVYQISWSADSR-LLLSGSKDSTLKVWDIRAR-------KLKQDLPGHADEVYAV 369 +GH + Y +SW+ + L+LS S D T+ WDI A + K GH V V Sbjct: 169 KGHTKEGYGLSWNPNKEGLILSASDDQTVCHWDINANQNVAGELQAKDVFKGHESVVEDV 228 Query: 370 DWSPDGEKVV-SGGKDRALKLW 432 W + V S G D+ L +W Sbjct: 229 AWHVLHDGVFGSVGDDKKLLIW 250
>POF11_SCHPO (Q09855) F-box/WD-repeat protein pof11| Length = 506 Score = 67.4 bits (163), Expect = 3e-11 Identities = 40/143 (27%), Positives = 74/143 (51%), Gaps = 3/143 (2%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARM---TGHQKVVNHVYFSPDGQWLASASFDKSVKLWN 183 ++S S D T +W + +A M GH VN V +S + +AS D++++ W+ Sbjct: 316 IISSSRDHTARVWRLDATSPAEACMHVLRGHLASVNSVQYSSKTGLIVTASSDRTLRTWD 375 Query: 184 GITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVY 363 TG + H + ++ + ++SGS D T+++++ + KL + L GH D + Sbjct: 376 ITTGHCIRIIHAHQRGIACAQYNG--KFIVSGSSDLTIRIFEASSGKLLRMLQGHEDLIR 433 Query: 364 AVDWSPDGEKVVSGGKDRALKLW 432 V + + EK+VSGG D +++W Sbjct: 434 TVRF--NDEKIVSGGYDGTVRIW 454 Score = 57.4 bits (137), Expect = 3e-08 Identities = 38/144 (26%), Positives = 72/144 (50%), Gaps = 4/144 (2%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWN--- 183 LVSGS D T+ +W+ +++P GH V V S + ++ S+S D + ++W Sbjct: 276 LVSGSSDSTIIIWDWQ-NRRPLKVYFGHTDNVLGVVVSEN--YIISSSRDHTARVWRLDA 332 Query: 184 -GITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEV 360 + RGH+A V + +S+ + L+++ S D TL+ WDI + + H + Sbjct: 333 TSPAEACMHVLRGHLASVNSVQYSSKTGLIVTASSDRTLRTWDITTGHCIRIIHAHQRGI 392 Query: 361 YAVDWSPDGEKVVSGGKDRALKLW 432 + +G+ +VSG D ++++ Sbjct: 393 ACAQY--NGKFIVSGSSDLTIRIF 414 Score = 53.1 bits (126), Expect = 6e-07 Identities = 39/144 (27%), Positives = 67/144 (46%), Gaps = 4/144 (2%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 +VSGS D T+ +W+ S+ ++ GH V + F L S S D ++ +W+ Sbjct: 234 MVSGSKDRTVSVWDVN-SRFILYKLYGHSGSVLCLDFCRRRNLLVSGSSDSTIIIWDWQN 292 Query: 193 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQD----LPGHADEV 360 + + + GH +V + S ++S S+D T +VW + A + L GH V Sbjct: 293 RRPLKVYFGHTDNVLGVVVS--ENYIISSSRDHTARVWRLDATSPAEACMHVLRGHLASV 350 Query: 361 YAVDWSPDGEKVVSGGKDRALKLW 432 +V +S +V+ DR L+ W Sbjct: 351 NSVQYSSKTGLIVTASSDRTLRTW 374 Score = 52.0 bits (123), Expect = 1e-06 Identities = 25/74 (33%), Positives = 41/74 (55%) Frame = +1 Query: 211 FRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGE 390 FR + VY + + D +++SGSKD T+ VWD+ +R + L GH+ V +D+ Sbjct: 217 FRATLDSVYCVQY--DDEIMVSGSKDRTVSVWDVNSRFILYKLYGHSGSVLCLDFCRRRN 274 Query: 391 KVVSGGKDRALKLW 432 +VSG D + +W Sbjct: 275 LLVSGSSDSTIIIW 288 Score = 51.6 bits (122), Expect = 2e-06 Identities = 29/101 (28%), Positives = 51/101 (50%) Frame = +1 Query: 130 DGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWD 309 D + + S S D++V +W+ + + GH V + + LL+SGS DST+ +WD Sbjct: 230 DDEIMVSGSKDRTVSVWDVNSRFILYKLYGHSGSVLCLDFCRRRNLLVSGSSDSTIIIWD 289 Query: 310 IRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 + R+ + GH D V V S + ++S +D ++W Sbjct: 290 WQNRRPLKVYFGHTDNVLGVVVSEN--YIISSSRDHTARVW 328 Score = 37.7 bits (86), Expect = 0.027 Identities = 25/100 (25%), Positives = 53/100 (53%), Gaps = 1/100 (1%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 +VSGS D T+ ++E + K + + GH+ ++ V F+ + + S +D +V++WN T Sbjct: 402 IVSGSSDLTIRIFEASSGKLLRM-LQGHEDLIRTVRFNDEK--IVSGGYDGTVRIWNFNT 458 Query: 193 G-KFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWD 309 G + + V+ + + D R +++ + S + VW+ Sbjct: 459 GEQHCVLHNSRNSRVFGLQF--DHRRIIACTHSSEILVWN 496
>COPB2_YEAST (P41811) Coatomer subunit beta' (Beta'-coat protein) (Beta'-COP)| Length = 889 Score = 67.4 bits (163), Expect = 3e-11 Identities = 43/144 (29%), Positives = 69/144 (47%), Gaps = 4/144 (2%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSP-DGQWLASASFDKSVKLWN-G 186 ++SGSDD T+ LW + + GH+ V V F+P D AS D++VK+W+ G Sbjct: 112 VLSGSDDLTVKLWNWENNWALEQTFEGHEHFVMCVAFNPKDPSTFASGCLDRTVKVWSLG 171 Query: 187 ITGKFVTAFRGHVADVYQISWSA--DSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEV 360 + T G V + + D +++ S D T+K+WD + + L GH V Sbjct: 172 QSTPNFTLTTGQERGVNYVDYYPLPDKPYMITASDDLTIKIWDYQTKSCVATLEGHMSNV 231 Query: 361 YAVDWSPDGEKVVSGGKDRALKLW 432 + P ++SG +D LK+W Sbjct: 232 SFAVFHPTLPIIISGSEDGTLKIW 255 Score = 63.9 bits (154), Expect = 3e-10 Identities = 38/132 (28%), Positives = 66/132 (50%), Gaps = 2/132 (1%) Frame = +1 Query: 4 PXRLVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHV--YFSPDGQWLASASFDKSVKL 177 P SG D T+ +W S TG ++ VN+V Y PD ++ +AS D ++K+ Sbjct: 153 PSTFASGCLDRTVKVWSLGQSTPNFTLTTGQERGVNYVDYYPLPDKPYMITASDDLTIKI 212 Query: 178 WNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADE 357 W+ T V GH+++V + +++SGS+D TLK+W+ K+++ L + Sbjct: 213 WDYQTKSCVATLEGHMSNVSFAVFHPTLPIIISGSEDGTLKIWNSSTYKVEKTLNVGLER 272 Query: 358 VYAVDWSPDGEK 393 + + P G K Sbjct: 273 SWCIATHPTGRK 284 Score = 50.1 bits (118), Expect = 5e-06 Identities = 32/100 (32%), Positives = 49/100 (49%), Gaps = 2/100 (2%) Frame = +1 Query: 139 WLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRA 318 W+ S D ++++N TG+ V F H + I+ +LSGS D T+K+W+ Sbjct: 69 WIIVGSDDFRIRVFNYNTGEKVVDFEAHPDYIRSIAVHPTKPYVLSGSDDLTVKLWNWEN 128 Query: 319 R-KLKQDLPGHADEVYAVDWSP-DGEKVVSGGKDRALKLW 432 L+Q GH V V ++P D SG DR +K+W Sbjct: 129 NWALEQTFEGHEHFVMCVAFNPKDPSTFASGCLDRTVKVW 168 Score = 43.9 bits (102), Expect = 4e-04 Identities = 37/145 (25%), Positives = 61/145 (42%), Gaps = 5/145 (3%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 ++ GSDDF + ++ ++ H + + P ++ S S D +VKLWN Sbjct: 70 IIVGSDDFRIRVFNYNTGEKV-VDFEAHPDYIRSIAVHPTKPYVLSGSDDLTVKLWNWEN 128 Query: 193 G-KFVTAFRGHVADVYQISWS-ADSRLLLSGSKDSTLKVWDIRARKLKQDL-PGHADEVY 363 F GH V ++++ D SG D T+KVW + L G V Sbjct: 129 NWALEQTFEGHEHFVMCVAFNPKDPSTFASGCLDRTVKVWSLGQSTPNFTLTTGQERGVN 188 Query: 364 AVDW--SPDGEKVVSGGKDRALKLW 432 VD+ PD +++ D +K+W Sbjct: 189 YVDYYPLPDKPYMITASDDLTIKIW 213 Score = 43.9 bits (102), Expect = 4e-04 Identities = 27/109 (24%), Positives = 47/109 (43%) Frame = +1 Query: 106 VNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSK 285 V + F P W+ + + V+LWN T V + + V + A ++ GS Sbjct: 16 VKGIDFHPTEPWVLTTLYSGRVELWNYETQVEVRSIQVTETPVRAGKFIARKNWIIVGSD 75 Query: 286 DSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 D ++V++ + D H D + ++ P V+SG D +KLW Sbjct: 76 DFRIRVFNYNTGEKVVDFEAHPDYIRSIAVHPTKPYVLSGSDDLTVKLW 124
>SCON2_NEUCR (Q01277) Sulfur controller 2 (SCON2)| Length = 650 Score = 67.0 bits (162), Expect = 4e-11 Identities = 45/140 (32%), Positives = 68/140 (48%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 L +GS D T+ +W + + + GH + + F D L S S D ++K+WN T Sbjct: 307 LATGSYDTTIKIWNIETEECIRT-LVGHTAGIRALQF--DDSKLISGSLDHTIKVWNWHT 363 Query: 193 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVD 372 G+ ++ F H V IS D LL SGS D T+K++D +++ L GH+D V + Sbjct: 364 GECLSTFAAHTDSV--ISVHFDGHLLASGSSDKTVKIFDFNSKE-TYCLKGHSDWVNSTH 420 Query: 373 WSPDGEKVVSGGKDRALKLW 432 V S D +KLW Sbjct: 421 VDIKSRTVFSASDDTTIKLW 440 Score = 60.8 bits (146), Expect = 3e-09 Identities = 35/116 (30%), Positives = 59/116 (50%) Frame = +1 Query: 85 MTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSR 264 + GH+ V + D LA+ S+D ++K+WN T + + GH A + + + D Sbjct: 290 LKGHENGVTCLQL--DDNILATGSYDTTIKIWNIETEECIRTLVGHTAGIRALQF--DDS 345 Query: 265 LLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 L+SGS D T+KVW+ + H D V +V + DG + SG D+ +K++ Sbjct: 346 KLISGSLDHTIKVWNWHTGECLSTFAAHTDSVISVHF--DGHLLASGSSDKTVKIF 399 Score = 59.3 bits (142), Expect = 9e-09 Identities = 44/137 (32%), Positives = 70/137 (51%), Gaps = 5/137 (3%) Frame = +1 Query: 10 RLVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGI 189 +L+SGS D T+ +W + + + H V V+F DG LAS S DK+VK+++ Sbjct: 346 KLISGSLDHTIKVWN-WHTGECLSTFAAHTDSVISVHF--DGHLLASGSSDKTVKIFD-F 401 Query: 190 TGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAV 369 K +GH V SR + S S D+T+K+WD+ R++ + GH V V Sbjct: 402 NSKETYCLKGHSDWVNSTHVDIKSRTVFSASDDTTIKLWDLDTRQVIRTYEGHVGHVQQV 461 Query: 370 -----DWSPDGEKVVSG 405 ++ PD E+V++G Sbjct: 462 LILPPEYEPD-EEVLNG 477 Score = 47.8 bits (112), Expect = 3e-05 Identities = 25/98 (25%), Positives = 49/98 (50%) Frame = +1 Query: 136 QWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIR 315 ++ + D +++LW+ TG+ + GH+ V+ ++ D+ ++SG+ D +K W+ R Sbjct: 549 RYFMTGGLDSTMRLWDSATGRCLRTLFGHLEGVWSLA--GDTIRVISGANDGMVKTWEPR 606 Query: 316 ARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKL 429 + K GH V V S + SG +D ++L Sbjct: 607 SGKCDATYTGHCGPVTCVGLS--DSLMASGSEDGTIRL 642 Score = 42.7 bits (99), Expect = 8e-04 Identities = 27/98 (27%), Positives = 48/98 (48%), Gaps = 5/98 (5%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 L SGS D T+ +++ + + + GH VN + + + SAS D ++KLW+ T Sbjct: 387 LASGSSDKTVKIFD--FNSKETYCLKGHSDWVNSTHVDIKSRTVFSASDDTTIKLWDLDT 444 Query: 193 GKFVTAFRGHVADVYQI-----SWSADSRLLLSGSKDS 291 + + + GHV V Q+ + D +L S+D+ Sbjct: 445 RQVIRTYEGHVGHVQQVLILPPEYEPDEEVLNGASQDN 482 Score = 38.5 bits (88), Expect = 0.016 Identities = 18/57 (31%), Positives = 33/57 (57%) Frame = +1 Query: 262 RLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 R ++G DST+++WD + + L GH + V+++ + D +V+SG D +K W Sbjct: 549 RYFMTGGLDSTMRLWDSATGRCLRTLFGHLEGVWSL--AGDTIRVISGANDGMVKTW 603
>HAT2_USTMA (Q4P553) Histone acetyltransferase type B subunit 2 (EC 2.3.1.48)| Length = 485 Score = 67.0 bits (162), Expect = 4e-11 Identities = 45/152 (29%), Positives = 77/152 (50%), Gaps = 12/152 (7%) Frame = +1 Query: 13 LVSGSDDFTMFLWE------PTISKQPKARMTGHQKVVNHVYFSPDGQWL-ASASFDKSV 171 +++ S+D T+ W+ P + QP A TGH +V V + + L S D+ + Sbjct: 257 ILAASEDTTVCHWDINNYTKPNNTLQPSATYTGHTAIVEDVAWHNHHESLFGSVGDDRQL 316 Query: 172 KLWNGITGKFVTAFR--GHVADVYQISWSADSR-LLLSGSKDSTLKVWDIRARKLK-QDL 339 +W+ +R H +V +++S ++ +L++GS D ++ VWD+R K+K L Sbjct: 317 LIWDIREPASAPKYRVEAHTGEVNALAFSPENENILVTGSSDKSVGVWDLRNLKVKLHSL 376 Query: 340 PGHADEVYAVDWSPDGEKVV-SGGKDRALKLW 432 H DE+ +V WSP V+ S DR + LW Sbjct: 377 ESHTDEILSVCWSPHHATVLASASADRRVNLW 408 Score = 33.9 bits (76), Expect = 0.38 Identities = 29/114 (25%), Positives = 48/114 (42%), Gaps = 16/114 (14%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPD-GQWLASASFDKSVKLWN-- 183 LV+GS D ++ +W+ K + H + V +SP LASAS D+ V LW+ Sbjct: 352 LVTGSSDKSVGVWDLRNLKVKLHSLESHTDEILSVCWSPHHATVLASASADRRVNLWDLS 411 Query: 184 ------------GITGKFVTAFRGHVADVYQISWSADSR-LLLSGSKDSTLKVW 306 + + GH + ++WS L S ++D+ + VW Sbjct: 412 KIGQEQTPDDAEDGPPELIFVHGGHTSRPTDLAWSPHMEWALTSAAEDNIVMVW 465
>WDR31_HUMAN (Q8NA23) WD-repeat protein 31| Length = 367 Score = 67.0 bits (162), Expect = 4e-11 Identities = 42/143 (29%), Positives = 65/143 (45%), Gaps = 5/143 (3%) Frame = +1 Query: 19 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 198 S S D + +W+ S QP+ ++ GH VV + SPD L + S D ++ LW+ +TG+ Sbjct: 120 SASRDRMVMMWDLHGSSQPRQQLCGHAMVVTGLAVSPDSSQLCTGSRDNTLLLWDVVTGQ 179 Query: 199 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWS 378 V V + W +L S+D TL++WD R ++ P + S Sbjct: 180 SVERASVSRNVVTHLCWVPREPYILQTSEDKTLRLWDSRGLQVAHMFPAKQHIQTYCEVS 239 Query: 379 PDGEKVVS-----GGKDRALKLW 432 DG K +S GG+ LW Sbjct: 240 VDGHKCISCSNGFGGEGCEATLW 262 Score = 58.2 bits (139), Expect = 2e-08 Identities = 31/96 (32%), Positives = 51/96 (53%), Gaps = 1/96 (1%) Frame = +1 Query: 148 SASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIR-ARK 324 S DK+V +N TG V F+GH ++ +++ S S S+D + +WD+ + + Sbjct: 78 SGGKDKTVVAYNWKTGNVVKRFKGHEHEITKVACIPKSSQFFSASRDRMVMMWDLHGSSQ 137 Query: 325 LKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 +Q L GHA V + SPD ++ +G +D L LW Sbjct: 138 PRQQLCGHAMVVTGLAVSPDSSQLCTGSRDNTLLLW 173 Score = 52.4 bits (124), Expect = 1e-06 Identities = 39/141 (27%), Positives = 64/141 (45%), Gaps = 2/141 (1%) Frame = +1 Query: 16 VSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITG 195 VSG D T+ + K R GH+ + V P SAS D+ V +W+ + G Sbjct: 77 VSGGKDKTVVAYNWKTGNVVK-RFKGHEHEITKVACIPKSSQFFSASRDRMVMMWD-LHG 134 Query: 196 KFVTAFR--GHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAV 369 + GH V ++ S DS L +GS+D+TL +WD+ + + + V + Sbjct: 135 SSQPRQQLCGHAMVVTGLAVSPDSSQLCTGSRDNTLLLWDVVTGQSVERASVSRNVVTHL 194 Query: 370 DWSPDGEKVVSGGKDRALKLW 432 W P ++ +D+ L+LW Sbjct: 195 CWVPREPYILQTSEDKTLRLW 215 Score = 35.8 bits (81), Expect = 0.10 Identities = 17/68 (25%), Positives = 32/68 (47%) Frame = +1 Query: 229 DVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGG 408 D + + +S L +SG KD T+ ++ + + + GH E+ V P + S Sbjct: 63 DTVSVVAALNSDLCVSGGKDKTVVAYNWKTGNVVKRFKGHEHEITKVACIPKSSQFFSAS 122 Query: 409 KDRALKLW 432 +DR + +W Sbjct: 123 RDRMVMMW 130
>WDR48_PONPY (Q5RAW8) WD-repeat protein 48| Length = 677 Score = 66.6 bits (161), Expect = 5e-11 Identities = 42/149 (28%), Positives = 71/149 (47%), Gaps = 9/149 (6%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 L+S S D T+ +W T H+ V + ++ D + +ASA D+ + LW+ T Sbjct: 90 LISASSDTTVKVWNAHKGFCMSTLRT-HKDYVKALAYAKDKELVASAGLDRQIFLWDVNT 148 Query: 193 GKFVTA---------FRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPG 345 +TA G+ +Y ++ + +++SGS + L+VWD R L G Sbjct: 149 LTALTASNNTVTTSSLSGNKDSIYSLAMNQLGTIIVSGSTEKVLRVWDPRTCAKLMKLKG 208 Query: 346 HADEVYAVDWSPDGEKVVSGGKDRALKLW 432 H D V A+ + DG + +SG D ++LW Sbjct: 209 HTDNVKALLLNRDGTQCLSGSSDGTIRLW 237 Score = 65.1 bits (157), Expect = 2e-10 Identities = 41/152 (26%), Positives = 69/152 (45%), Gaps = 11/152 (7%) Frame = +1 Query: 10 RLVSGSDDFTMFLWEPTISKQPK--ARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWN 183 RL + D + +W KQ A M H VN + +G+ L SAS D +VK+WN Sbjct: 44 RLFTAGRDSIIRIWSVNQHKQDPYIASMEHHTDWVNDIVLCCNGKTLISASSDTTVKVWN 103 Query: 184 GITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRA---------RKLKQD 336 G ++ R H V ++++ D L+ S D + +WD+ Sbjct: 104 AHKGFCMSTLRTHKDYVKALAYAKDKELVASAGLDRQIFLWDVNTLTALTASNNTVTTSS 163 Query: 337 LPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 L G+ D +Y++ + G +VSG ++ L++W Sbjct: 164 LSGNKDSIYSLAMNQLGTIIVSGSTEKVLRVW 195 Score = 50.1 bits (118), Expect = 5e-06 Identities = 32/145 (22%), Positives = 67/145 (46%), Gaps = 8/145 (5%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTI--------SKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKS 168 + S D +FLW+ + + ++G++ + + + G + S S +K Sbjct: 132 VASAGLDRQIFLWDVNTLTALTASNNTVTTSSLSGNKDSIYSLAMNQLGTIIVSGSTEKV 191 Query: 169 VKLWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGH 348 +++W+ T + +GH +V + + D LSGS D T+++W + ++ H Sbjct: 192 LRVWDPRTCAKLMKLKGHTDNVKALLLNRDGTQCLSGSSDGTIRLWSLGQQRCIATYRVH 251 Query: 349 ADEVYAVDWSPDGEKVVSGGKDRAL 423 + V+A+ + V SGG+DR + Sbjct: 252 DEGVWALQVNDAFTHVYSGGRDRKI 276 Score = 41.2 bits (95), Expect = 0.002 Identities = 27/102 (26%), Positives = 50/102 (49%), Gaps = 1/102 (0%) Frame = +1 Query: 13 LVSGSDDFTMFLWEP-TISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGI 189 +VSGS + + +W+P T +K K + GH V + + DG S S D +++LW+ Sbjct: 183 IVSGSTEKVLRVWDPRTCAKLMKLK--GHTDNVKALLLNRDGTQCLSGSSDGTIRLWSLG 240 Query: 190 TGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIR 315 + + +R H V+ + + + SG +D + D+R Sbjct: 241 QQRCIATYRVHDEGVWALQVNDAFTHVYSGGRDRKIYCTDLR 282
>WDR48_HUMAN (Q8TAF3) WD-repeat protein 48 (WD repeat endosomal protein) (p80)| Length = 677 Score = 66.6 bits (161), Expect = 5e-11 Identities = 42/149 (28%), Positives = 71/149 (47%), Gaps = 9/149 (6%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 L+S S D T+ +W T H+ V + ++ D + +ASA D+ + LW+ T Sbjct: 90 LISASSDTTVKVWNAHKGFCMSTLRT-HKDYVKALAYAKDKELVASAGLDRQIFLWDVNT 148 Query: 193 GKFVTA---------FRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPG 345 +TA G+ +Y ++ + +++SGS + L+VWD R L G Sbjct: 149 LTALTASNNTVTTSSLSGNKDSIYSLAMNQLGTIIVSGSTEKVLRVWDPRTCAKLMKLKG 208 Query: 346 HADEVYAVDWSPDGEKVVSGGKDRALKLW 432 H D V A+ + DG + +SG D ++LW Sbjct: 209 HTDNVKALLLNRDGTQCLSGSSDGTIRLW 237 Score = 65.1 bits (157), Expect = 2e-10 Identities = 41/152 (26%), Positives = 69/152 (45%), Gaps = 11/152 (7%) Frame = +1 Query: 10 RLVSGSDDFTMFLWEPTISKQPK--ARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWN 183 RL + D + +W KQ A M H VN + +G+ L SAS D +VK+WN Sbjct: 44 RLFTAGRDSIIRIWSVNQHKQDPYIASMEHHTDWVNDIVLCCNGKTLISASSDTTVKVWN 103 Query: 184 GITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRA---------RKLKQD 336 G ++ R H V ++++ D L+ S D + +WD+ Sbjct: 104 AHKGFCMSTLRTHKDYVKALAYAKDKELVASAGLDRQIFLWDVNTLTALTASNNTVTTSS 163 Query: 337 LPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 L G+ D +Y++ + G +VSG ++ L++W Sbjct: 164 LSGNKDSIYSLAMNQLGTIIVSGSTEKVLRVW 195 Score = 50.1 bits (118), Expect = 5e-06 Identities = 32/145 (22%), Positives = 67/145 (46%), Gaps = 8/145 (5%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTI--------SKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKS 168 + S D +FLW+ + + ++G++ + + + G + S S +K Sbjct: 132 VASAGLDRQIFLWDVNTLTALTASNNTVTTSSLSGNKDSIYSLAMNQLGTIIVSGSTEKV 191 Query: 169 VKLWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGH 348 +++W+ T + +GH +V + + D LSGS D T+++W + ++ H Sbjct: 192 LRVWDPRTCAKLMKLKGHTDNVKALLLNRDGTQCLSGSSDGTIRLWSLGQQRCIATYRVH 251 Query: 349 ADEVYAVDWSPDGEKVVSGGKDRAL 423 + V+A+ + V SGG+DR + Sbjct: 252 DEGVWALQVNDAFTHVYSGGRDRKI 276 Score = 41.2 bits (95), Expect = 0.002 Identities = 27/102 (26%), Positives = 50/102 (49%), Gaps = 1/102 (0%) Frame = +1 Query: 13 LVSGSDDFTMFLWEP-TISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGI 189 +VSGS + + +W+P T +K K + GH V + + DG S S D +++LW+ Sbjct: 183 IVSGSTEKVLRVWDPRTCAKLMKLK--GHTDNVKALLLNRDGTQCLSGSSDGTIRLWSLG 240 Query: 190 TGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIR 315 + + +R H V+ + + + SG +D + D+R Sbjct: 241 QQRCIATYRVHDEGVWALQVNDAFTHVYSGGRDRKIYCTDLR 282
>WDR48_BRARE (Q6PFM9) WD-repeat protein 48| Length = 677 Score = 66.6 bits (161), Expect = 5e-11 Identities = 41/149 (27%), Positives = 71/149 (47%), Gaps = 9/149 (6%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 L+S S D T+ +W T H+ V + ++ D + +ASA D+ + LW+ T Sbjct: 90 LISASSDTTVKVWNAHKGFCMSTLRT-HKDYVKALAYAKDKELVASAGLDRQIFLWDVNT 148 Query: 193 GKFVTA---------FRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPG 345 +TA G+ +Y ++ + +++SGS + L+VWD R L G Sbjct: 149 LTALTASNNTVTTSSLSGNKDSIYSLAMNQTGTVIISGSTEKVLRVWDPRTCAKLMKLKG 208 Query: 346 HADEVYAVDWSPDGEKVVSGGKDRALKLW 432 H D V ++ + DG + +SG D ++LW Sbjct: 209 HTDNVKSLLLNRDGTQCLSGSSDGTIRLW 237 Score = 66.2 bits (160), Expect = 7e-11 Identities = 40/152 (26%), Positives = 69/152 (45%), Gaps = 11/152 (7%) Frame = +1 Query: 10 RLVSGSDDFTMFLWEPTISKQPK--ARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWN 183 RL + D + +W KQ A M H VN + +G+ L SAS D +VK+WN Sbjct: 44 RLFTAGRDSIIRIWSVNQHKQDPYIASMEHHTDWVNDIILCCNGKTLISASSDTTVKVWN 103 Query: 184 GITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRA---------RKLKQD 336 G ++ R H V ++++ D L+ S D + +WD+ Sbjct: 104 AHKGFCMSTLRTHKDYVKALAYAKDKELVASAGLDRQIFLWDVNTLTALTASNNTVTTSS 163 Query: 337 LPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 L G+ D +Y++ + G ++SG ++ L++W Sbjct: 164 LSGNKDSIYSLAMNQTGTVIISGSTEKVLRVW 195 Score = 50.8 bits (120), Expect = 3e-06 Identities = 31/145 (21%), Positives = 67/145 (46%), Gaps = 8/145 (5%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTI--------SKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKS 168 + S D +FLW+ + + ++G++ + + + G + S S +K Sbjct: 132 VASAGLDRQIFLWDVNTLTALTASNNTVTTSSLSGNKDSIYSLAMNQTGTVIISGSTEKV 191 Query: 169 VKLWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGH 348 +++W+ T + +GH +V + + D LSGS D T+++W + ++ H Sbjct: 192 LRVWDPRTCAKLMKLKGHTDNVKSLLLNRDGTQCLSGSSDGTIRLWSLGQQRCIATYRVH 251 Query: 349 ADEVYAVDWSPDGEKVVSGGKDRAL 423 + V+A+ + + SGG+DR + Sbjct: 252 DEGVWALQVNEAFTHIYSGGRDRKI 276 Score = 42.0 bits (97), Expect = 0.001 Identities = 26/102 (25%), Positives = 50/102 (49%), Gaps = 1/102 (0%) Frame = +1 Query: 13 LVSGSDDFTMFLWEP-TISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGI 189 ++SGS + + +W+P T +K K + GH V + + DG S S D +++LW+ Sbjct: 183 IISGSTEKVLRVWDPRTCAKLMKLK--GHTDNVKSLLLNRDGTQCLSGSSDGTIRLWSLG 240 Query: 190 TGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIR 315 + + +R H V+ + + + SG +D + D+R Sbjct: 241 QQRCIATYRVHDEGVWALQVNEAFTHIYSGGRDRKIYCTDLR 282
>WDR48_CHICK (Q5F3K4) WD-repeat protein 48| Length = 678 Score = 66.6 bits (161), Expect = 5e-11 Identities = 42/149 (28%), Positives = 71/149 (47%), Gaps = 9/149 (6%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 L+S S D T+ +W T H+ V + ++ D + +ASA D+ + LW+ T Sbjct: 90 LISASSDTTVKVWNAHKGFCMSTLRT-HKDYVKALAYAKDKELVASAGLDRQIFLWDVNT 148 Query: 193 GKFVTA---------FRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPG 345 +TA G+ +Y ++ + +++SGS + L+VWD R L G Sbjct: 149 LTALTASNNTVTTSSLSGNKDSIYSLAMNQMGTVIVSGSTEKVLRVWDPRTCAKLMKLKG 208 Query: 346 HADEVYAVDWSPDGEKVVSGGKDRALKLW 432 H D V A+ + DG + +SG D ++LW Sbjct: 209 HTDNVKALLLNRDGTQCLSGSSDGTIRLW 237 Score = 65.9 bits (159), Expect = 9e-11 Identities = 41/152 (26%), Positives = 69/152 (45%), Gaps = 11/152 (7%) Frame = +1 Query: 10 RLVSGSDDFTMFLWEPTISKQPK--ARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWN 183 RL + D + +W KQ A M H VN + +G+ L SAS D +VK+WN Sbjct: 44 RLFTAGRDSIIRIWSVNQHKQDPYIASMEHHTDWVNDIVLCCNGKTLISASSDTTVKVWN 103 Query: 184 GITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRA---------RKLKQD 336 G ++ R H V ++++ D L+ S D + +WD+ Sbjct: 104 AHKGFCMSTLRTHKDYVKALAYAKDKELVASAGLDRQIFLWDVNTLTALTASNNTVTTSS 163 Query: 337 LPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 L G+ D +Y++ + G +VSG ++ L++W Sbjct: 164 LSGNKDSIYSLAMNQMGTVIVSGSTEKVLRVW 195 Score = 50.4 bits (119), Expect = 4e-06 Identities = 32/145 (22%), Positives = 67/145 (46%), Gaps = 8/145 (5%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTI--------SKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKS 168 + S D +FLW+ + + ++G++ + + + G + S S +K Sbjct: 132 VASAGLDRQIFLWDVNTLTALTASNNTVTTSSLSGNKDSIYSLAMNQMGTVIVSGSTEKV 191 Query: 169 VKLWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGH 348 +++W+ T + +GH +V + + D LSGS D T+++W + ++ H Sbjct: 192 LRVWDPRTCAKLMKLKGHTDNVKALLLNRDGTQCLSGSSDGTIRLWSLGQQRCIATYRVH 251 Query: 349 ADEVYAVDWSPDGEKVVSGGKDRAL 423 + V+A+ + V SGG+DR + Sbjct: 252 DEGVWALQVNEAFTHVYSGGRDRKI 276 Score = 41.6 bits (96), Expect = 0.002 Identities = 27/102 (26%), Positives = 50/102 (49%), Gaps = 1/102 (0%) Frame = +1 Query: 13 LVSGSDDFTMFLWEP-TISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGI 189 +VSGS + + +W+P T +K K + GH V + + DG S S D +++LW+ Sbjct: 183 IVSGSTEKVLRVWDPRTCAKLMKLK--GHTDNVKALLLNRDGTQCLSGSSDGTIRLWSLG 240 Query: 190 TGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIR 315 + + +R H V+ + + + SG +D + D+R Sbjct: 241 QQRCIATYRVHDEGVWALQVNEAFTHVYSGGRDRKIYCTDLR 282
>WDR48_MACFA (Q4R2Z6) WD-repeat protein 48| Length = 622 Score = 66.6 bits (161), Expect = 5e-11 Identities = 42/149 (28%), Positives = 71/149 (47%), Gaps = 9/149 (6%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 L+S S D T+ +W T H+ V + ++ D + +ASA D+ + LW+ T Sbjct: 90 LISASSDTTVKVWNAHKGFCMSTLRT-HKDYVKALAYAKDKELVASAGLDRQIFLWDVNT 148 Query: 193 GKFVTA---------FRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPG 345 +TA G+ +Y ++ + +++SGS + L+VWD R L G Sbjct: 149 LTALTASNNTVTTSSLSGNKDSIYSLAMNQLGTIIVSGSTEKVLRVWDPRTCAKLMKLKG 208 Query: 346 HADEVYAVDWSPDGEKVVSGGKDRALKLW 432 H D V A+ + DG + +SG D ++LW Sbjct: 209 HTDNVKALLLNRDGTQCLSGSSDGTIRLW 237 Score = 65.1 bits (157), Expect = 2e-10 Identities = 41/152 (26%), Positives = 69/152 (45%), Gaps = 11/152 (7%) Frame = +1 Query: 10 RLVSGSDDFTMFLWEPTISKQPK--ARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWN 183 RL + D + +W KQ A M H VN + +G+ L SAS D +VK+WN Sbjct: 44 RLFTAGRDSIIRIWSVNQHKQDPYIASMEHHTDWVNDIVLCCNGKTLISASSDTTVKVWN 103 Query: 184 GITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRA---------RKLKQD 336 G ++ R H V ++++ D L+ S D + +WD+ Sbjct: 104 AHKGFCMSTLRTHKDYVKALAYAKDKELVASAGLDRQIFLWDVNTLTALTASNNTVTTSS 163 Query: 337 LPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 L G+ D +Y++ + G +VSG ++ L++W Sbjct: 164 LSGNKDSIYSLAMNQLGTIIVSGSTEKVLRVW 195 Score = 50.1 bits (118), Expect = 5e-06 Identities = 32/145 (22%), Positives = 67/145 (46%), Gaps = 8/145 (5%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTI--------SKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKS 168 + S D +FLW+ + + ++G++ + + + G + S S +K Sbjct: 132 VASAGLDRQIFLWDVNTLTALTASNNTVTTSSLSGNKDSIYSLAMNQLGTIIVSGSTEKV 191 Query: 169 VKLWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGH 348 +++W+ T + +GH +V + + D LSGS D T+++W + ++ H Sbjct: 192 LRVWDPRTCAKLMKLKGHTDNVKALLLNRDGTQCLSGSSDGTIRLWSLGQQRCIATYRVH 251 Query: 349 ADEVYAVDWSPDGEKVVSGGKDRAL 423 + V+A+ + V SGG+DR + Sbjct: 252 DEGVWALQVNDAFTHVYSGGRDRKI 276 Score = 41.2 bits (95), Expect = 0.002 Identities = 27/102 (26%), Positives = 50/102 (49%), Gaps = 1/102 (0%) Frame = +1 Query: 13 LVSGSDDFTMFLWEP-TISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGI 189 +VSGS + + +W+P T +K K + GH V + + DG S S D +++LW+ Sbjct: 183 IVSGSTEKVLRVWDPRTCAKLMKLK--GHTDNVKALLLNRDGTQCLSGSSDGTIRLWSLG 240 Query: 190 TGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIR 315 + + +R H V+ + + + SG +D + D+R Sbjct: 241 QQRCIATYRVHDEGVWALQVNDAFTHVYSGGRDRKIYCTDLR 282
>WDR3_HUMAN (Q9UNX4) WD-repeat protein 3| Length = 943 Score = 66.6 bits (161), Expect = 5e-11 Identities = 37/114 (32%), Positives = 57/114 (50%) Frame = +1 Query: 91 GHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLL 270 GH+ V + S DG +A+ S D++VK+W G + H V + + S L Sbjct: 589 GHKLPVICMDISHDGALIATGSADRNVKIWGLDFGDCHKSLFAHDDSVMYLQFVPKSHLF 648 Query: 271 LSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 + KD +K WD + Q L GH E++ + SP G+ VVS D++L+LW Sbjct: 649 FTAGKDHKIKQWDADKFEHIQTLEGHHQEIWCLAVSPSGDYVVSSSHDKSLRLW 702 Score = 59.7 bits (143), Expect = 7e-09 Identities = 29/124 (23%), Positives = 61/124 (49%) Frame = +1 Query: 61 ISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQ 240 +S + GH+ + + + G LAS S D + +W+ I + +GH + Q Sbjct: 95 LSGEGNVTFNGHKAAITTLKYDQLGGRLASGSKDTDIIVWDVINESGLYRLKGHKDAITQ 154 Query: 241 ISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRA 420 + + LL++ KD+ +K WD+ + + + GH EV+ + + +++++G D Sbjct: 155 ALFLREKNLLVTSGKDTMVKWWDLDTQHCFKTMVGHRTEVWGLVLLSEEKRLITGASDSE 214 Query: 421 LKLW 432 L++W Sbjct: 215 LRVW 218 Score = 58.5 bits (140), Expect = 1e-08 Identities = 37/133 (27%), Positives = 62/133 (46%), Gaps = 12/133 (9%) Frame = +1 Query: 10 RLVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGI 189 RL SGS D + +W+ I++ R+ GH+ + F + L ++ D VK W+ Sbjct: 121 RLASGSKDTDIIVWD-VINESGLYRLKGHKDAITQALFLREKNLLVTSGKDTMVKWWDLD 179 Query: 190 TGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIR------------ARKLKQ 333 T GH +V+ + ++ + L++G+ DS L+VWDI +K+K Sbjct: 180 TQHCFKTMVGHRTEVWGLVLLSEEKRLITGASDSELRVWDIAYLQEIEDPEEPDPKKIKG 239 Query: 334 DLPGHADEVYAVD 372 PG D + A D Sbjct: 240 SSPGIQDTLEAED 252 Score = 58.2 bits (139), Expect = 2e-08 Identities = 38/132 (28%), Positives = 66/132 (50%), Gaps = 1/132 (0%) Frame = +1 Query: 40 MFLWEPTISKQPKAR-MTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFR 216 +F+W+ + K K + G ++ V + SPDG LA D S+++++ ++G+ F Sbjct: 47 VFIWD--LRKGEKILILQGLKQEVTCLCPSPDGLHLAVGYEDGSIRIFSLLSGEGNVTFN 104 Query: 217 GHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKV 396 GH A + + + L SGSKD+ + VWD+ L GH D + + + + Sbjct: 105 GHKAAITTLKYDQLGGRLASGSKDTDIIVWDVINESGLYRLKGHKDAITQALFLREKNLL 164 Query: 397 VSGGKDRALKLW 432 V+ GKD +K W Sbjct: 165 VTSGKDTMVKWW 176 Score = 55.5 bits (132), Expect = 1e-07 Identities = 32/106 (30%), Positives = 51/106 (48%) Frame = +1 Query: 115 VYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDST 294 V +SP+ + LA + D +VK++ T KF + GH V + S D L+ +GS D Sbjct: 555 VSYSPNQKLLAVSLLDCTVKIFYVDTLKFFLSLYGHKLPVICMDISHDGALIATGSADRN 614 Query: 295 LKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 +K+W + + L H D V + + P + GKD +K W Sbjct: 615 VKIWGLDFGDCHKSLFAHDDSVMYLQFVPKSHLFFTAGKDHKIKQW 660 Score = 51.6 bits (122), Expect = 2e-06 Identities = 36/129 (27%), Positives = 65/129 (50%), Gaps = 3/129 (2%) Frame = +1 Query: 55 PTISKQPKARMT--GHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVA 228 PT +R+T GH+ V + FS D + SA+ D S+K+WN T + R Sbjct: 399 PTPQPVRTSRITIGGHRSDVRTLSFSSDNIAVLSAAAD-SIKIWNRST---LQCIRTMTC 454 Query: 229 DVYQISWSADS-RLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSG 405 + S+ R ++ G+K L+++D+ + L + + H ++++ SPD V+G Sbjct: 455 EYALCSFFVPGDRQVVIGTKTGKLQLYDLASGNLLETIDAHDGALWSMSLSPDQRGFVTG 514 Query: 406 GKDRALKLW 432 G D+++K W Sbjct: 515 GADKSVKFW 523 Score = 50.8 bits (120), Expect = 3e-06 Identities = 34/124 (27%), Positives = 56/124 (45%), Gaps = 11/124 (8%) Frame = +1 Query: 94 HQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVA-----------DVYQ 240 H + + SPD + + DKSVK W+ K + + ++ DV Sbjct: 495 HDGALWSMSLSPDQRGFVTGGADKSVKFWDFELVKDENSTQKRLSVKQTRTLQLDEDVLC 554 Query: 241 ISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRA 420 +S+S + +LL D T+K++ + K L GH V +D S DG + +G DR Sbjct: 555 VSYSPNQKLLAVSLLDCTVKIFYVDTLKFFLSLYGHKLPVICMDISHDGALIATGSADRN 614 Query: 421 LKLW 432 +K+W Sbjct: 615 VKIW 618 Score = 40.0 bits (92), Expect = 0.005 Identities = 21/99 (21%), Positives = 45/99 (45%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 + +GS D + +W K+ + H V ++ F P +A D +K W+ Sbjct: 606 IATGSADRNVKIWGLDFGDCHKS-LFAHDDSVMYLQFVPKSHLFFTAGKDHKIKQWDADK 664 Query: 193 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWD 309 + + GH +++ ++ S ++S S D +L++W+ Sbjct: 665 FEHIQTLEGHHQEIWCLAVSPSGDYVVSSSHDKSLRLWE 703
>PFS2_YEAST (P42841) Protein PFS2| Length = 465 Score = 66.2 bits (160), Expect = 7e-11 Identities = 37/141 (26%), Positives = 63/141 (44%) Frame = +1 Query: 10 RLVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGI 189 RLV + LW + S + M H V + +S D W+ S D +K+W Sbjct: 107 RLVVATYSGEFSLWNAS-SFTFETLMQAHDSAVTTMKYSHDSDWMISGDADGMIKIWQPN 165 Query: 190 TGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAV 369 H + +++S++ ++ S D+ LK+W+ K ++ L GH +V + Sbjct: 166 FSMVKEIDAAHTESIRDMAFSSNDSKFVTCSDDNILKIWNFSNGKQERVLSGHHWDVKSC 225 Query: 370 DWSPDGEKVVSGGKDRALKLW 432 DW P+ + S KD +KLW Sbjct: 226 DWHPEMGLIASASKDNLVKLW 246 Score = 60.1 bits (144), Expect = 5e-09 Identities = 29/110 (26%), Positives = 55/110 (50%) Frame = +1 Query: 103 VVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGS 282 V+ + ++P+G+ L A++ LWN + F T + H + V + +S DS ++SG Sbjct: 95 VIPAIQWTPEGRRLVVATYSGEFSLWNASSFTFETLMQAHDSAVTTMKYSHDSDWMISGD 154 Query: 283 KDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 D +K+W +K+ H + + + +S + K V+ D LK+W Sbjct: 155 ADGMIKIWQPNFSMVKEIDAAHTESIRDMAFSSNDSKFVTCSDDNILKIW 204 Score = 59.3 bits (142), Expect = 9e-09 Identities = 36/141 (25%), Positives = 64/141 (45%), Gaps = 1/141 (0%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 192 ++SG D + +W+P S K H + + + FS + + S D +K+WN Sbjct: 150 MISGDADGMIKIWQPNFS-MVKEIDAAHTESIRDMAFSSNDSKFVTCSDDNILKIWNFSN 208 Query: 193 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVD 372 GK GH DV W + L+ S SKD+ +K+WD R+ + V Sbjct: 209 GKQERVLSGHHWDVKSCDWHPEMGLIASASKDNLVKLWDPRSGNCISSILKFKHTVLKTR 268 Query: 373 WSP-DGEKVVSGGKDRALKLW 432 + P G +++ KD++ +++ Sbjct: 269 FQPTKGNLLMAISKDKSCRVF 289
>FZR_HUMAN (Q9UM11) Fizzy-related protein homolog (Fzr) (Cdh1/Hct1 homolog)| (hCDH1) (CDC20-like protein 1) Length = 496 Score = 66.2 bits (160), Expect = 7e-11 Identities = 41/134 (30%), Positives = 67/134 (50%), Gaps = 3/134 (2%) Frame = +1 Query: 40 MFLWEPTISKQPK-ARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFR 216 ++LW S+ + ++ V V +S G +A + V++W+ GK ++ Sbjct: 209 VYLWSACTSQVTRLCDLSVEGDSVTSVGWSERGNLVAVGTHKGFVQIWDAAAGKKLSMLE 268 Query: 217 GHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQD--LPGHADEVYAVDWSPDGE 390 GH A V ++W+A+ L SGS+D + DIR L+ + L GH EV + WS D + Sbjct: 269 GHTARVGALAWNAEQ--LSSGSRDRMILQRDIRTPPLQSERRLQGHRQEVCGLKWSTDHQ 326 Query: 391 KVVSGGKDRALKLW 432 + SGG D L +W Sbjct: 327 LLASGGNDNKLLVW 340 Score = 61.2 bits (147), Expect = 2e-09 Identities = 40/145 (27%), Positives = 69/145 (47%), Gaps = 5/145 (3%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASA---SFDKSVKLWN 183 L SG +D + +W + S P + T H V + +SP L ++ + D+ ++ WN Sbjct: 328 LASGGNDNKLLVWNHS-SLSPVQQYTEHLAAVKAIAWSPHQHGLLASGGGTADRCIRFWN 386 Query: 184 GITGKFVTAFRGHVADVYQISWSADSRLLLS--GSKDSTLKVWDIRARKLKQDLPGHADE 357 +TG+ + + V ++WS + L+S G + + VW + L GH+ Sbjct: 387 TLTGQPLQCIDTG-SQVCNLAWSKHANELVSTHGYSQNQILVWKYPSLTQVAKLTGHSYR 445 Query: 358 VYAVDWSPDGEKVVSGGKDRALKLW 432 V + SPDGE +V+G D L+ W Sbjct: 446 VLYLAMSPDGEAIVTGAGDETLRFW 470 Score = 49.3 bits (116), Expect = 9e-06 Identities = 25/76 (32%), Positives = 38/76 (50%), Gaps = 3/76 (3%) Frame = +1 Query: 214 RGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEK 393 +GH +V + WS D +LL SG D+ L VW+ + Q H V A+ WSP Sbjct: 310 QGHRQEVCGLKWSTDHQLLASGGNDNKLLVWNHSSLSPVQQYTEHLAAVKAIAWSPHQHG 369 Query: 394 VVSGG---KDRALKLW 432 +++ G DR ++ W Sbjct: 370 LLASGGGTADRCIRFW 385 Score = 39.7 bits (91), Expect = 0.007 Identities = 26/94 (27%), Positives = 40/94 (42%), Gaps = 2/94 (2%) Frame = +1 Query: 148 SASFDKSVKLWNGITGKFVTAFRGHVA--DVYQISWSADSRLLLSGSKDSTLKVWDIRAR 321 S V LW+ T + V V + WS L+ G+ +++WD A Sbjct: 202 SVGLGTCVYLWSACTSQVTRLCDLSVEGDSVTSVGWSERGNLVAVGTHKGFVQIWDAAAG 261 Query: 322 KLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRAL 423 K L GH V A+ W + E++ SG +DR + Sbjct: 262 KKLSMLEGHTARVGALAW--NAEQLSSGSRDRMI 293 Score = 33.5 bits (75), Expect = 0.50 Identities = 12/35 (34%), Positives = 24/35 (68%) Frame = +1 Query: 79 ARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWN 183 A++TGH V ++ SPDG+ + + + D++++ WN Sbjct: 437 AKLTGHSYRVLYLAMSPDGEAIVTGAGDETLRFWN 471
>COPB2_RAT (O35142) Coatomer subunit beta' (Beta'-coat protein) (Beta'-COP)| (p102) Length = 904 Score = 66.2 bits (160), Expect = 7e-11 Identities = 38/143 (26%), Positives = 66/143 (46%), Gaps = 3/143 (2%) Frame = +1 Query: 13 LVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSP-DGQWLASASFDKSVKLWNGI 189 +++ SDD + LW+ GH V + +P D ASAS D+++K+W Sbjct: 113 ILTSSDDMLIKLWDWDKKWSCSQVFEGHTHYVMQIVINPKDNNQFASASLDRTIKVWQLG 172 Query: 190 TGKFVTAFRGHVADVYQISW--SADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVY 363 + GH V I + D L+SG+ D +K+WD + + Q GHA V Sbjct: 173 SSSPNFTLEGHEKGVNCIDYYSGGDKPYLISGADDRLVKIWDYQNKTCVQTPEGHAQNVS 232 Query: 364 AVDWSPDGEKVVSGGKDRALKLW 432 + P+ +++G +D +++W Sbjct: 233 CATFHPELPIIITGSEDGTVRIW 255 Score = 53.1 bits (126), Expect = 6e-07 Identities = 33/122 (27%), Positives = 61/122 (50%), Gaps = 2/122 (1%) Frame = +1 Query: 10 RLVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHV--YFSPDGQWLASASFDKSVKLWN 183 + S S D T+ +W+ S P + GH+K VN + Y D +L S + D+ VK+W+ Sbjct: 156 QFASASLDRTIKVWQLG-SSSPNFTLEGHEKGVNCIDYYSGGDKPYLISGADDRLVKIWD 214 Query: 184 GITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVY 363 V GH +V ++ + ++++GS+D T+++W +L+ L + V+ Sbjct: 215 YQNKTCVQTPEGHAQNVSCATFHPELPIIITGSEDGTVRIWHSSTYRLESTLNYGMERVW 274 Query: 364 AV 369 V Sbjct: 275 CV 276 Score = 42.4 bits (98), Expect = 0.001 Identities = 25/119 (21%), Positives = 50/119 (42%) Frame = +1 Query: 76 KARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSA 255 K ++T V V P W+ ++ ++ SV +WN T V F V + A Sbjct: 7 KRKLTAMSDRVKSVDLHPTEPWMLASLYNGSVCVWNHETQTLVKTFEVCDLPVRAAKFVA 66 Query: 256 DSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 +++G+ D ++V++ + H+D + + P +++ D +KLW Sbjct: 67 RKNWVVTGADDMQIRVFNYNTLERVHMFEAHSDYIRCIAVHPTQPFILTSSDDMLIKLW 125
>GBB2_TOBAC (P93398) Guanine nucleotide-binding protein beta subunit 2| Length = 377 Score = 66.2 bits (160), Expect = 7e-11 Identities = 44/152 (28%), Positives = 69/152 (45%), Gaps = 9/152 (5%) Frame = +1 Query: 4 PXRLVSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWN 183 P VSGS D T LW+ ++ + + GH+ VN V F PDG + S D + +L++ Sbjct: 217 PRLFVSGSCDSTARLWDTRVASRAQRTFYGHEGDVNTVKFFPDGNRFGTGSDDGTCRLFD 276 Query: 184 GITGKFVTAF-----RGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDL--- 339 TG + + G + V +++S RLL G + VWD K+ +L Sbjct: 277 IRTGHQLQVYYQPHGDGDIPHVTSMAFSISGRLLFVGYSNGDCYVWDTLLAKVVLNLGAV 336 Query: 340 -PGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 H + + S DG + +G D LK+W Sbjct: 337 QNSHEGRISCLGLSADGSALCTGSWDTNLKIW 368 Score = 65.1 bits (157), Expect = 2e-10 Identities = 44/129 (34%), Positives = 71/129 (55%), Gaps = 9/129 (6%) Frame = +1 Query: 73 PKARM-TGHQKVVNHVYFSPDGQW-LASASFDKSVKLWNGITGKFVTAF-----RGHVAD 231 P +RM +GH+ V+ + PD + ++S D++ LW+ TG + F GH AD Sbjct: 147 PVSRMLSGHKGYVSSCQYVPDEDTHVITSSGDQTCVLWDITTGLRTSVFGGEFQSGHTAD 206 Query: 232 VYQISWSADS-RLLLSGSKDSTLKVWDIR-ARKLKQDLPGHADEVYAVDWSPDGEKVVSG 405 V +S S+ + RL +SGS DST ++WD R A + ++ GH +V V + PDG + +G Sbjct: 207 VQSVSISSSNPRLFVSGSCDSTARLWDTRVASRAQRTFYGHEGDVNTVKFFPDGNRFGTG 266 Query: 406 GKDRALKLW 432 D +L+ Sbjct: 267 SDDGTCRLF 275 Score = 40.8 bits (94), Expect = 0.003 Identities = 19/73 (26%), Positives = 33/73 (45%) Frame = +1 Query: 214 RGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEK 393 +GH VY + W+ + ++S S+D L VW+ + + V +SP G+ Sbjct: 62 QGHTGKVYSLDWTPEKNRIVSASQDGRLIVWNALTSQKTHAIKLPCAWVMTCAFSPSGQS 121 Query: 394 VVSGGKDRALKLW 432 V GG D ++ Sbjct: 122 VACGGLDSVCSIF 134 Score = 40.0 bits (92), Expect = 0.005 Identities = 28/124 (22%), Positives = 56/124 (45%), Gaps = 8/124 (6%) Frame = +1 Query: 85 MTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSR 264 + GH V + ++P+ + SAS D + +WN +T + A + A V ++S + Sbjct: 61 LQGHTGKVYSLDWTPEKNRIVSASQDGRLIVWNALTSQKTHAIKLPCAWVMTCAFSPSGQ 120 Query: 265 LLLSGSKDSTLKVWDIRA-------RKLKQDLPGHADEVYAVDWSPDGE-KVVSGGKDRA 420 + G DS ++++ + + + L GH V + + PD + V++ D+ Sbjct: 121 SVACGGLDSVCSIFNLNSPIDKDGNHPVSRMLSGHKGYVSSCQYVPDEDTHVITSSGDQT 180 Query: 421 LKLW 432 LW Sbjct: 181 CVLW 184
>GBB_DICDI (P36408) Guanine nucleotide-binding protein beta subunit| Length = 347 Score = 65.9 bits (159), Expect = 9e-11 Identities = 36/116 (31%), Positives = 60/116 (51%) Frame = +1 Query: 85 MTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSR 264 + H ++ F D Q + ++S D + LW+ G +T F H DV +S S D Sbjct: 146 LNSHTGYLSCCRFLNDRQ-IVTSSGDMTCILWDVENGTKITEFSDHNGDVMSVSVSPDKN 204 Query: 265 LLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 +SG+ D+T K+WD+R+ K Q GH ++ AV + P+G +G D + +L+ Sbjct: 205 YFISGACDATAKLWDLRSGKCVQTFTGHEADINAVQYFPNGLSFGTGSDDASCRLF 260 Score = 58.9 bits (141), Expect = 1e-08 Identities = 42/144 (29%), Positives = 71/144 (49%), Gaps = 3/144 (2%) Frame = +1 Query: 10 RLVSGSDDFTMFLWEPTISKQPK-ARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNG 186 ++V+ S D T LW+ + K + H V V SPD + S + D + KLW+ Sbjct: 163 QIVTSSGDMTCILWD--VENGTKITEFSDHNGDVMSVSVSPDKNYFISGACDATAKLWDL 220 Query: 187 ITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRA-RKLKQDLPGH-ADEV 360 +GK V F GH AD+ + + + +GS D++ +++DIRA R+L Q + + Sbjct: 221 RSGKCVQTFTGHEADINAVQYFPNGLSFGTGSDDASCRLFDIRADRELMQYTHDNILCGI 280 Query: 361 YAVDWSPDGEKVVSGGKDRALKLW 432 +V +S G + +G D +W Sbjct: 281 TSVGFSFSGRFLFAGYDDFTCNVW 304 Score = 58.2 bits (139), Expect = 2e-08 Identities = 38/141 (26%), Positives = 64/141 (45%), Gaps = 2/141 (1%) Frame = +1 Query: 16 VSGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITG 195 +SG+ D T LW+ K + TGH+ +N V + P+G + S D S +L++ Sbjct: 207 ISGACDATAKLWDLRSGKCVQT-FTGHEADINAVQYFPNGLSFGTGSDDASCRLFDIRAD 265 Query: 196 KFVTAFRGH--VADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAV 369 + + + + + + +S R L +G D T VWD + L GH + V + Sbjct: 266 RELMQYTHDNILCGITSVGFSFSGRFLFAGYDDFTCNVWDTLKGERVLSLTGHGNRVSCL 325 Query: 370 DWSPDGEKVVSGGKDRALKLW 432 DG + +G D LK+W Sbjct: 326 GVPTDGMALCTGSWDSLLKIW 346 Score = 44.3 bits (103), Expect = 3e-04 Identities = 22/73 (30%), Positives = 35/73 (47%) Frame = +1 Query: 214 RGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEK 393 +GH+A +Y + W+ D+ L+S S+D L VWD +P + V +SP Sbjct: 59 KGHLAKIYAMHWAEDNVHLVSASQDGKLLVWDGLTTNKVHAIPLRSSWVMTCAYSPTANF 118 Query: 394 VVSGGKDRALKLW 432 V GG D ++ Sbjct: 119 VACGGLDNICSIY 131 Score = 39.7 bits (91), Expect = 0.007 Identities = 28/123 (22%), Positives = 57/123 (46%), Gaps = 4/123 (3%) Frame = +1 Query: 76 KARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSA 255 + + GH + ++++ D L SAS D + +W+G+T V A + V ++S Sbjct: 55 RRNLKGHLAKIYAMHWAEDNVHLVSASQDGKLLVWDGLTTNKVHAIPLRSSWVMTCAYSP 114 Query: 256 DSRLLLSGSKDSTLKVWDIRAR----KLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRAL 423 + + G D+ ++++R+R ++ ++L H + + D + V S G D Sbjct: 115 TANFVACGGLDNICSIYNLRSREQPIRVCRELNSHTGYLSCCRFLNDRQIVTSSG-DMTC 173 Query: 424 KLW 432 LW Sbjct: 174 ILW 176 Score = 35.4 bits (80), Expect = 0.13 Identities = 13/37 (35%), Positives = 24/37 (64%) Frame = +1 Query: 322 KLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 432 K++++L GH ++YA+ W+ D +VS +D L +W Sbjct: 53 KVRRNLKGHLAKIYAMHWAEDNVHLVSASQDGKLLVW 89 Database: uniprot_sprot.fasta Posted date: May 25, 2006 5:36 PM Number of letters in database: 80,573,946 Number of sequences in database: 219,361 Lambda K H 0.318 0.135 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 92,348,585 Number of Sequences: 219361 Number of extensions: 1993746 Number of successful extensions: 10761 Number of sequences better than 10.0: 500 Number of HSP's better than 10.0 without gapping: 5814 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 8448 length of database: 80,573,946 effective HSP length: 107 effective length of database: 57,102,319 effective search space used: 5481822624 frameshift window, decay const: 50, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
