ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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| Clone Name | baak4j19 |
|---|---|
| Clone Library Name | barley_pub |
>ABCBA_MOUSE (Q9JI39) ATP-binding cassette sub-family B member 10, mitochondrial| precursor (ATP-binding cassette transporter 10) (ABC transporter 10 protein) (ABC-mitochondrial erythroid protein) (ABC-me protein) Length = 715 Score = 136 bits (342), Expect = 4e-32 Identities = 73/180 (40%), Positives = 104/180 (57%) Frame = +2 Query: 5 LRAWLFNSASERVVARLRQDLFSHLINQEIAFFDVTRTGELLSRLSEDTQIIKNAATTNL 184 +R +L S+ + +V RLR LFS ++ QE+AFFD TRTGEL++RLS DT ++ + T NL Sbjct: 196 IRVYLMQSSGQSIVNRLRTSLFSSILRQEVAFFDKTRTGELINRLSSDTALLGRSVTENL 255 Query: 185 SEALRNLTTTAIGLGFMFSTSWKLTLLALVIVPVISVAVRKFGRFLRELSHQTQXXXXXX 364 S+ LR ++G+G MF S L L +VP ISV +GR+LR+LS TQ Sbjct: 256 SDGLRAGAQASVGVGMMFFVSPSLATFVLSVVPPISVLAVIYGRYLRKLSKATQDSLAEA 315 Query: 365 XXXXXXXFGAIRTVRAFAQEPHEISRYGGKVNETLKLGLKQAKVVGLFSGGLNAASTLSV 544 G IRT+RAF +E E+ +Y G+V++ L+L K+A F G + L V Sbjct: 316 TQLAEERIGNIRTIRAFGKEMTEVEKYTGRVDQLLQLAQKEALARAGFFGAAGLSGNLIV 375
>ABCBA_HUMAN (Q9NRK6) ATP-binding cassette sub-family B member 10, mitochondrial| precursor (ATP-binding cassette transporter 10) (ABC transporter 10 protein) (Mitochondrial ATP-binding cassette 2) (M-ABC2) Length = 738 Score = 133 bits (335), Expect = 3e-31 Identities = 70/181 (38%), Positives = 103/181 (56%) Frame = +2 Query: 2 ALRAWLFNSASERVVARLRQDLFSHLINQEIAFFDVTRTGELLSRLSEDTQIIKNAATTN 181 A+R +L ++ +R+V RLR LFS ++ QE+AFFD TRTGEL++RLS DT ++ + T N Sbjct: 230 AIRVYLMQTSGQRIVNRLRTSLFSSILRQEVAFFDKTRTGELINRLSSDTALLGRSVTEN 289 Query: 182 LSEALRNLTTTAIGLGFMFSTSWKLTLLALVIVPVISVAVRKFGRFLRELSHQTQXXXXX 361 LS+ LR ++G+ MF S L L +VP +S+ +GR+LR+L+ TQ Sbjct: 290 LSDGLRAGAQASVGISMMFFVSPNLATFVLSVVPPVSIIAVIYGRYLRKLTKVTQDSLAQ 349 Query: 362 XXXXXXXXFGAIRTVRAFAQEPHEISRYGGKVNETLKLGLKQAKVVGLFSGGLNAASTLS 541 G +RTVRAF +E EI +Y KV+ ++L K+A F G + L Sbjct: 350 ATQLAEERIGNVRTVRAFGKEMTEIEKYASKVDHVMQLARKEAVARAGFFGATGLSGNLI 409 Query: 542 V 544 V Sbjct: 410 V 410
>MDL1_YEAST (P33310) ATP-dependent permease MDL1, mitochondrial precursor (ABC| transporter MDL1) (Multidrug resistance-like protein 1) Length = 695 Score = 111 bits (278), Expect = 1e-24 Identities = 58/171 (33%), Positives = 86/171 (50%) Frame = +2 Query: 2 ALRAWLFNSASERVVARLRQDLFSHLINQEIAFFDVTRTGELLSRLSEDTQIIKNAATTN 181 A R + ER+VARLR ++Q+ F D R G+L+SRLS D I+ + T N Sbjct: 171 ASRIIILKVTGERLVARLRTRTMKAALDQDATFLDTNRVGDLISRLSSDASIVAKSVTQN 230 Query: 182 LSEALRNLTTTAIGLGFMFSTSWKLTLLALVIVPVISVAVRKFGRFLRELSHQTQXXXXX 361 +S+ R + +G G M SWKLT + +++ P + +GR +R LS Q Q Sbjct: 231 VSDGTRAIIQGFVGFGMMSFLSWKLTCVMMILAPPLGAMALIYGRKIRNLSRQLQTSVGG 290 Query: 362 XXXXXXXXFGAIRTVRAFAQEPHEISRYGGKVNETLKLGLKQAKVVGLFSG 514 A RT++A+ E +E+ RY +V +GLK+A GLF G Sbjct: 291 LTKVAEEQLNATRTIQAYGGEKNEVRRYAKEVRNVFHIGLKEAVTSGLFFG 341
>ABCB9_HUMAN (Q9NP78) ATP-binding cassette sub-family B member 9 precursor| (ATP-binding cassette transporter 9) (ABC transporter 9 protein) (TAP-like protein) (TAPL) (hABCB9) Length = 766 Score = 104 bits (260), Expect = 1e-22 Identities = 55/162 (33%), Positives = 88/162 (54%) Frame = +2 Query: 5 LRAWLFNSASERVVARLRQDLFSHLINQEIAFFDVTRTGELLSRLSEDTQIIKNAATTNL 184 +R +F R+ RLR LF L++QE +FFD RTG+L+SRL+ DT ++ + + N+ Sbjct: 245 IRGGIFTLIFARLNIRLRNCLFRSLVSQETSFFDENRTGDLISRLTSDTTMVSDLVSQNI 304 Query: 185 SEALRNLTTTAIGLGFMFSTSWKLTLLALVIVPVISVAVRKFGRFLRELSHQTQXXXXXX 364 + LRN + FMFS SW+L+L+ + P+I + +G++ + LS + Q Sbjct: 305 NVFLRNTVKVTGVVVFMFSLSWQLSLVTFMGFPIIMMVSNIYGKYYKRLSKEVQNALARA 364 Query: 365 XXXXXXXFGAIRTVRAFAQEPHEISRYGGKVNETLKLGLKQA 490 A++TVR+FA E E Y K+ + KL K+A Sbjct: 365 SNTAEETISAMKTVRSFANEEEEAEVYLRKLQQVYKLNRKEA 406
>ABCB9_RAT (Q9QYJ4) ATP-binding cassette sub-family B member 9 precursor| (ATP-binding cassette transporter 9) (ABC transporter 9 protein) (TAP-like protein) (TAPL) Length = 762 Score = 103 bits (258), Expect = 2e-22 Identities = 54/162 (33%), Positives = 88/162 (54%) Frame = +2 Query: 5 LRAWLFNSASERVVARLRQDLFSHLINQEIAFFDVTRTGELLSRLSEDTQIIKNAATTNL 184 +R +F R+ RLR LF L++QE +FFD RTG+L+SRL+ DT ++ + + N+ Sbjct: 241 IRGGIFTLVFARLNIRLRNCLFRSLVSQETSFFDENRTGDLISRLTSDTTMVSDLVSQNI 300 Query: 185 SEALRNLTTTAIGLGFMFSTSWKLTLLALVIVPVISVAVRKFGRFLRELSHQTQXXXXXX 364 + LRN + FMFS SW+L+L+ + P+I + +G++ + LS + Q Sbjct: 301 NIFLRNTVKVTGVVVFMFSLSWQLSLVTFMGFPIIMMVSNIYGKYYKRLSKEVQSALARA 360 Query: 365 XXXXXXXFGAIRTVRAFAQEPHEISRYGGKVNETLKLGLKQA 490 A++TVR+FA E E + K+ + KL K+A Sbjct: 361 STTAEETISAMKTVRSFANEEEEAEVFLRKLQQVYKLNRKEA 402
>ABCB9_MOUSE (Q9JJ59) ATP-binding cassette sub-family B member 9 precursor| (ATP-binding cassette transporter 9) (ABC transporter 9 protein) (TAP-like protein) (TAPL) (mABCB9) Length = 762 Score = 103 bits (258), Expect = 2e-22 Identities = 54/162 (33%), Positives = 88/162 (54%) Frame = +2 Query: 5 LRAWLFNSASERVVARLRQDLFSHLINQEIAFFDVTRTGELLSRLSEDTQIIKNAATTNL 184 +R +F R+ RLR LF L++QE +FFD RTG+L+SRL+ DT ++ + + N+ Sbjct: 241 IRGGIFTLVFARLNIRLRNCLFRSLVSQETSFFDENRTGDLISRLTSDTTMVSDLVSQNI 300 Query: 185 SEALRNLTTTAIGLGFMFSTSWKLTLLALVIVPVISVAVRKFGRFLRELSHQTQXXXXXX 364 + LRN + FMFS SW+L+L+ + P+I + +G++ + LS + Q Sbjct: 301 NIFLRNTVKVTGVVVFMFSLSWQLSLVTFMGFPIIMMVSNIYGKYYKRLSKEVQSALARA 360 Query: 365 XXXXXXXFGAIRTVRAFAQEPHEISRYGGKVNETLKLGLKQA 490 A++TVR+FA E E + K+ + KL K+A Sbjct: 361 STTAEETISAMKTVRSFANEEEEAEVFLRKLQQVYKLNRKEA 402
>MDL1_CANAL (P97998) ATP-dependent permease MDL1| Length = 685 Score = 99.4 bits (246), Expect = 6e-21 Identities = 52/173 (30%), Positives = 90/173 (52%), Gaps = 6/173 (3%) Frame = +2 Query: 8 RAWLFNSASERVVARLRQDLFSHLINQEIAFFDV------TRTGELLSRLSEDTQIIKNA 169 R +L S ER+VARLR LFS ++ Q+ FFD+ +TG+L+SR++ DTQII + Sbjct: 176 RIYLLRSVGERLVARLRSRLFSKILAQDAYFFDLGPSKTGMKTGDLISRIASDTQIISKS 235 Query: 170 ATTNLSEALRNLTTTAIGLGFMFSTSWKLTLLALVIVPVISVAVRKFGRFLRELSHQTQX 349 + N+S+ +R + + +GL M SWKL+L +I P + +GR ++ LS Q Sbjct: 236 LSMNISDGIRAIISGCVGLSMMCYVSWKLSLCMSLIFPPLITMSWFYGRKIKALSKLIQE 295 Query: 350 XXXXXXXXXXXXFGAIRTVRAFAQEPHEISRYGGKVNETLKLGLKQAKVVGLF 508 ++ ++ F+Q+ + Y ++ +++AK+ G F Sbjct: 296 NIGDMTKVTEEKLNGVKVIQTFSQQQSVVHSYNQEIKNIFNSSMREAKLAGFF 348
>YNT9_SCHPO (Q9Y7M7) Probable ATP-dependent permease C9B6.09c| Length = 726 Score = 96.7 bits (239), Expect = 4e-20 Identities = 53/161 (32%), Positives = 87/161 (54%) Frame = +2 Query: 32 SERVVARLRQDLFSHLINQEIAFFDVTRTGELLSRLSEDTQIIKNAATTNLSEALRNLTT 211 SER+V+RLR LF+ ++ + AFFD + G+L+SRL+ D+ I+ + + LS+ LR+ + Sbjct: 230 SERIVSRLRARLFAKCMSLDGAFFDFHKHGDLISRLTTDSSIVGKSLSMYLSDGLRSSVS 289 Query: 212 TAIGLGFMFSTSWKLTLLALVIVPVISVAVRKFGRFLRELSHQTQXXXXXXXXXXXXXFG 391 G+G M S +LT +IVP I++ +G ++R+LS TQ Sbjct: 290 AIAGIGMMLYVSMRLTGYMSLIVPPIALGAFFYGEYVRKLSRTTQDALGDLTRVSEEKLA 349 Query: 392 AIRTVRAFAQEPHEISRYGGKVNETLKLGLKQAKVVGLFSG 514 +RT +AF E E++RY + L ++A G+F G Sbjct: 350 NVRTTQAFLGERQEVNRYNDYIRNLFVLAKREAFASGIFFG 390
>MSBA_DESPS (Q6AJW3) Lipid A export ATP-binding/permease protein msbA| Length = 572 Score = 94.0 bits (232), Expect = 2e-19 Identities = 46/161 (28%), Positives = 84/161 (52%) Frame = +2 Query: 11 AWLFNSASERVVARLRQDLFSHLINQEIAFFDVTRTGELLSRLSEDTQIIKNAATTNLSE 190 A + + ++ R +F+H+ Q ++FF T TG L+SR+ D +++ A +T + + Sbjct: 80 AIILERVGQSIIRDFRLKIFAHIHRQSLSFFHNTPTGTLISRVLSDVALMQQAVSTVIIQ 139 Query: 191 ALRNLTTTAIGLGFMFSTSWKLTLLALVIVPVISVAVRKFGRFLRELSHQTQXXXXXXXX 370 LR+ LG +F +WKL L+ +I+P+ ++ + KFG+ R+LS +TQ Sbjct: 140 LLRDFFQVIFLLGVIFYMNWKLALICFLIIPLAAIPIVKFGKIFRKLSTKTQEETAEVSN 199 Query: 371 XXXXXFGAIRTVRAFAQEPHEISRYGGKVNETLKLGLKQAK 493 R V+AF +E +E+ R+ +V + +K AK Sbjct: 200 MLHETISGSRIVKAFCREDYEVERFHRQVETLFTITMKNAK 240
>ABCB8_HUMAN (Q9NUT2) ATP-binding cassette sub-family B member 8, mitochondrial| precursor (Mitochondrial ATP-binding cassette 1) (M-ABC1) Length = 735 Score = 92.8 bits (229), Expect = 5e-19 Identities = 58/171 (33%), Positives = 84/171 (49%) Frame = +2 Query: 17 LFNSASERVVARLRQDLFSHLINQEIAFFDVTRTGELLSRLSEDTQIIKNAATTNLSEAL 196 L + ER+ +R+ LFS L+ Q I FFD +TG+L+SRL+ D Q K++ +S+ L Sbjct: 215 LLSHVGERMAVDMRRALFSSLLRQNITFFDANKTGQLVSRLTTDVQEFKSSFKLVISQGL 274 Query: 197 RNLTTTAIGLGFMFSTSWKLTLLALVIVPVISVAVRKFGRFLRELSHQTQXXXXXXXXXX 376 R+ + A L + S +LTLL +V P + G LR+LS Q Q Sbjct: 275 RSCSQVAGCLVSLSMLSTRLTLLLMVATPALMGVGTLMGSGLRKLSRQCQEHIARAMGVA 334 Query: 377 XXXFGAIRTVRAFAQEPHEISRYGGKVNETLKLGLKQAKVVGLFSGGLNAA 529 G +RTVRA A E E RYG ++ + + + LF G N A Sbjct: 335 DEALGNVRTVRALAMEQREEERYGAELEACRCRAEELGRGIALFQGLSNIA 385
>TAP2_HUMAN (Q03519) Antigen peptide transporter 2 (APT2) (Peptide transporter| TAP2) (Peptide transporter PSF2) (Peptide supply factor 2) (PSF-2) (Peptide transporter involved in antigen processing 2) Length = 686 Score = 92.0 bits (227), Expect = 9e-19 Identities = 52/146 (35%), Positives = 76/146 (52%) Frame = +2 Query: 8 RAWLFNSASERVVARLRQDLFSHLINQEIAFFDVTRTGELLSRLSEDTQIIKNAATTNLS 187 R F R+ R+R+ LFS L+ Q++ FF T+TGEL SRLS DT ++ N N + Sbjct: 210 RGGCFTYTMSRINLRIREQLFSSLLRQDLGFFQETKTGELNSRLSSDTTLMSNWLPLNAN 269 Query: 188 EALRNLTTTAIGLGFMFSTSWKLTLLALVIVPVISVAVRKFGRFLRELSHQTQXXXXXXX 367 LR+L GFM S S +LTLL+L+ +P A + + +E+ + Q Sbjct: 270 VLLRSLVKVVGLYGFMLSISPRLTLLSLLHMPFTIAAEKVYNTRHQEVLREIQDAVARAG 329 Query: 368 XXXXXXFGAIRTVRAFAQEPHEISRY 445 G ++TVR+F E HE+ RY Sbjct: 330 QVVREAVGGLQTVRSFGAEEHEVCRY 355
>MDL2_YEAST (P33311) ATP-dependent permease MDL2, mitochondrial precursor| (Multidrug resistance-like protein 2) Length = 773 Score = 90.9 bits (224), Expect = 2e-18 Identities = 47/154 (30%), Positives = 80/154 (51%) Frame = +2 Query: 17 LFNSASERVVARLRQDLFSHLINQEIAFFDVTRTGELLSRLSEDTQIIKNAATTNLSEAL 196 L SERVVARLR ++ ++Q+ FFD + G+L+SRL D ++ + T +S+ + Sbjct: 191 LLRILSERVVARLRANVIKKTLHQDAEFFDNHKVGDLISRLGSDAYVVSRSMTQKVSDGV 250 Query: 197 RNLTTTAIGLGFMFSTSWKLTLLALVIVPVISVAVRKFGRFLRELSHQTQXXXXXXXXXX 376 + L +G+G M S S +L++L L P + + FG+ +R S Q Sbjct: 251 KALICGVVGVGMMCSLSPQLSILLLFFTPPVLFSASVFGKQIRNTSKDLQEATGQLTRVA 310 Query: 377 XXXFGAIRTVRAFAQEPHEISRYGGKVNETLKLG 478 I+TV++F E +E+SRY + + ++G Sbjct: 311 EEQLSGIKTVQSFVAEGNELSRYNVAIRDIFQVG 344
>MDR1_RAT (P43245) Multidrug resistance protein 1 (EC 3.6.3.44)| (P-glycoprotein 1) (CD243 antigen) Length = 1277 Score = 88.2 bits (217), Expect = 1e-17 Identities = 48/162 (29%), Positives = 82/162 (50%) Frame = +2 Query: 29 ASERVVARLRQDLFSHLINQEIAFFDVTRTGELLSRLSEDTQIIKNAATTNLSEALRNLT 208 A+ R + ++RQ F ++NQEI +FDV GEL +RL++D I + L +++T Sbjct: 138 AAGRQIHKIRQKFFHAIMNQEIGWFDVNDAGELNTRLTDDVSKINDGIGDKLGMFFQSIT 197 Query: 209 TTAIGLGFMFSTSWKLTLLALVIVPVISVAVRKFGRFLRELSHQTQXXXXXXXXXXXXXF 388 T + G F + WKLTL+ L + P+I ++ + + L +++ Sbjct: 198 TFSAGFIIGFISGWKLTLVILAVSPLIGLSSAMWAKVLTSFTNKELQAYAKAGAVAEEVL 257 Query: 389 GAIRTVRAFAQEPHEISRYGGKVNETLKLGLKQAKVVGLFSG 514 AIRTV AF + E+ RY + E ++G+K+A + G Sbjct: 258 AAIRTVIAFGGQKKELERYNKNLEEAKRVGIKKAITANISIG 299 Score = 58.5 bits (140), Expect = 1e-08 Identities = 44/170 (25%), Positives = 78/170 (45%), Gaps = 4/170 (2%) Frame = +2 Query: 8 RAWLFNSASERVVARLRQDLFSHLINQEIAFFDVTR--TGELLSRLSEDTQIIKNAATTN 181 + + F A E + RLR +F ++ Q+I++FD + TG L +RL+ D +K A + Sbjct: 771 QGFTFGKAGEILTKRLRYMVFKSMLRQDISWFDDHKNTTGSLTTRLASDASNVKGAMGSR 830 Query: 182 LSEALRNLTT--TAIGLGFMFSTSWKLTLLALVIVPVISVAVRKFGRFLRELSHQTQXXX 355 L+ +N+ T I L + W+LTLL +VI+P+I + + L + + + Sbjct: 831 LAVVTQNVANLGTGIILSLVLVYGWQLTLLLVVIIPLIVLGGIIEMKLLSGQALKDKKEL 890 Query: 356 XXXXXXXXXXFGAIRTVRAFAQEPHEISRYGGKVNETLKLGLKQAKVVGL 505 RTV + +E + Y + + LK+A V G+ Sbjct: 891 EISGKIATEAIENFRTVVSLTREQKFETMYAQSLQIPYRNALKKAHVFGI 940
>ABCBB_RAT (O70127) Bile salt export pump (ATP-binding cassette sub-family B| member 11) (Sister of P-glycoprotein) Length = 1321 Score = 87.4 bits (215), Expect = 2e-17 Identities = 50/170 (29%), Positives = 81/170 (47%) Frame = +2 Query: 5 LRAWLFNSASERVVARLRQDLFSHLINQEIAFFDVTRTGELLSRLSEDTQIIKNAATTNL 184 +R W+ A R + R+R+ F ++ EI +FD T GEL SR ++D + I +A L Sbjct: 160 IRLWVITGA--RQIRRMRKIYFRRIMRMEIGWFDCTSVGELNSRFADDIEKINDAIADQL 217 Query: 185 SEALRNLTTTAIGLGFMFSTSWKLTLLALVIVPVISVAVRKFGRFLRELSHQTQXXXXXX 364 + L+ ++T GL F WKLTL+ L + P+I + G + + + Sbjct: 218 AHFLQRMSTAMCGLLLGFYRGWKLTLVILAVSPLIGIGAAVIGLSIAKFTELELKAYAKA 277 Query: 365 XXXXXXXFGAIRTVRAFAQEPHEISRYGGKVNETLKLGLKQAKVVGLFSG 514 +IRTV AF E E+ RY + + G+ + V+G F+G Sbjct: 278 GSIADEVLSSIRTVAAFGGENKEVERYEKNLVFAQRWGIWKGMVMGFFTG 327 Score = 60.1 bits (144), Expect = 4e-09 Identities = 42/177 (23%), Positives = 78/177 (44%), Gaps = 5/177 (2%) Frame = +2 Query: 5 LRAWLFNSASERVVARLRQDLFSHLINQEIAFFDVTRT--GELLSRLSEDTQIIKNAATT 178 L+ + F + E + RLR+ F ++ Q+I +FD R G L +RL+ D ++ A + Sbjct: 815 LQGYTFAKSGELLTKRLRKFGFKAMLGQDIGWFDDLRNNPGVLTTRLATDASQVQGATGS 874 Query: 179 NLSEALRNLTTTAIGLGFMFSTSWKLTLLALVIVPVISVAVRKFGRFLRELSHQTQXXXX 358 + + + T L F SWKL+L+ + P ++++ + L + Q + Sbjct: 875 QVGMMVNSFTNIIAALLIAFFFSWKLSLIITIFFPFLALSGAVQTKMLTGFASQDKQALE 934 Query: 359 XXXXXXXXXFGAIRTVRAFAQEPHEISRYGGKVNETLKLGLKQAKVVGL---FSGGL 520 IRTV E I + ++ + K +++A + GL FS G+ Sbjct: 935 KAGQITSEALSNIRTVAGIGVEGRFIKAFEVELQTSYKTAVRKANIYGLCFAFSQGI 991
>MDR3_ARATH (Q9SYI2) Putative multidrug resistance protein 3 (P-glycoprotein 3)| Length = 1229 Score = 84.7 bits (208), Expect = 1e-16 Identities = 48/172 (27%), Positives = 86/172 (50%), Gaps = 2/172 (1%) Frame = +2 Query: 5 LRAWLFNSASERVVARLRQDLFSHLINQEIAFFD--VTRTGELLSRLSEDTQIIKNAATT 178 + +LF A R++ R+R F +++ E+ +FD +G + SRLS D +IK Sbjct: 721 MHTYLFAVAGGRLIQRIRVMCFEKVVHMEVGWFDDPENSSGTIGSRLSADAALIKTLVGD 780 Query: 179 NLSEALRNLTTTAIGLGFMFSTSWKLTLLALVIVPVISVAVRKFGRFLRELSHQTQXXXX 358 +LS +++N GL F+ SWKL ++ LV++P+I + +F++ + + Sbjct: 781 SLSLSVKNAAAAVSGLIIAFTASWKLAVIILVMIPLIGINGYLQIKFIKGFTADAKAKYE 840 Query: 359 XXXXXXXXXFGAIRTVRAFAQEPHEISRYGGKVNETLKLGLKQAKVVGLFSG 514 G+IRTV +F E + Y + +T+K G+KQ + G+ G Sbjct: 841 EASQVANDAVGSIRTVASFCAEEKVMEMYKKRCEDTIKSGIKQGLISGVGFG 892 Score = 77.0 bits (188), Expect = 3e-14 Identities = 48/161 (29%), Positives = 76/161 (47%), Gaps = 1/161 (0%) Frame = +2 Query: 35 ERVVARLRQDLFSHLINQEIAFFDV-TRTGELLSRLSEDTQIIKNAATTNLSEALRNLTT 211 ER AR+R ++ Q+I FFDV T TGE++ R+S DT +I A + + ++ + T Sbjct: 96 ERQAARIRSLYLKTILRQDIGFFDVETSTGEVVGRMSGDTVLILEAMGEKVGKFIQLIAT 155 Query: 212 TAIGLGFMFSTSWKLTLLALVIVPVISVAVRKFGRFLRELSHQTQXXXXXXXXXXXXXFG 391 G F W LTL+ LV +P++++A + S + Q G Sbjct: 156 FVGGFVLAFVKGWLLTLVMLVSIPLLAIAGAAMPIIVTRASSREQAAYAKASTVVEQTLG 215 Query: 392 AIRTVRAFAQEPHEISRYGGKVNETLKLGLKQAKVVGLFSG 514 +IRTV +F E + Y +N + +KQ +GL G Sbjct: 216 SIRTVASFTGEKQAMKSYREFINLAYRASVKQGFSMGLGLG 256
>MDR1_MOUSE (P06795) Multidrug resistance protein 1 (EC 3.6.3.44)| (P-glycoprotein 1) (CD243 antigen) Length = 1276 Score = 84.7 bits (208), Expect = 1e-16 Identities = 47/162 (29%), Positives = 80/162 (49%) Frame = +2 Query: 29 ASERVVARLRQDLFSHLINQEIAFFDVTRTGELLSRLSEDTQIIKNAATTNLSEALRNLT 208 A+ R + ++RQ F ++NQEI +FDV GEL +RL++D I + + +++T Sbjct: 138 AAGRQIHKIRQKFFHAIMNQEIGWFDVHDVGELNTRLTDDVSKINDGIGDKIGMFFQSIT 197 Query: 209 TTAIGLGFMFSTSWKLTLLALVIVPVISVAVRKFGRFLRELSHQTQXXXXXXXXXXXXXF 388 T G F + WKLTL+ L + P+I ++ + + L +++ Sbjct: 198 TFLAGFIIGFISGWKLTLVILAVSPLIGLSSALWAKVLTSFTNKELQAYAKAGAVAEEVL 257 Query: 389 GAIRTVRAFAQEPHEISRYGGKVNETLKLGLKQAKVVGLFSG 514 AIRTV AF + E+ RY + E +G+K+A + G Sbjct: 258 AAIRTVIAFGGQQKELERYNKNLEEAKNVGIKKAITASISIG 299 Score = 57.8 bits (138), Expect = 2e-08 Identities = 39/168 (23%), Positives = 75/168 (44%), Gaps = 2/168 (1%) Frame = +2 Query: 8 RAWLFNSASERVVARLRQDLFSHLINQEIAFFDVTR--TGELLSRLSEDTQIIKNAATTN 181 + + F A E + R+R +F ++ Q+I++FD + TG L +RL+ D +K A Sbjct: 771 QGFTFGKAGEILTKRVRYMVFKSMLRQDISWFDDHKNSTGSLTTRLASDASSVKGAMGAR 830 Query: 182 LSEALRNLTTTAIGLGFMFSTSWKLTLLALVIVPVISVAVRKFGRFLRELSHQTQXXXXX 361 L+ +N+ G+ W+LTLL +VI+P+I + + L + + + Sbjct: 831 LAVVTQNVANLGTGVILSLVYGWQLTLLLVVIIPLIVLGGIIEMKLLSGQALKDKKQLEI 890 Query: 362 XXXXXXXXFGAIRTVRAFAQEPHEISRYGGKVNETLKLGLKQAKVVGL 505 RT+ + +E + Y + + +K+A V G+ Sbjct: 891 SGKIATEAIENFRTIVSLTREQKFETMYAQSLQVPYRNAMKKAHVFGI 938
>ABCBB_MOUSE (Q9QY30) Bile salt export pump (ATP-binding cassette sub-family B| member 11) (Sister of P-glycoprotein) Length = 1321 Score = 84.3 bits (207), Expect = 2e-16 Identities = 50/170 (29%), Positives = 79/170 (46%) Frame = +2 Query: 5 LRAWLFNSASERVVARLRQDLFSHLINQEIAFFDVTRTGELLSRLSEDTQIIKNAATTNL 184 +R W+ A R + ++R+ F ++ EI +FD T GEL SR S+D I A + Sbjct: 160 IRLWVITGA--RQIRKMRKFYFRRIMRMEIGWFDCTSVGELNSRFSDDINKIDEAIADQM 217 Query: 185 SEALRNLTTTAIGLGFMFSTSWKLTLLALVIVPVISVAVRKFGRFLRELSHQTQXXXXXX 364 + L+ L+T GL F WKLTL+ L + P+I + G + + + Sbjct: 218 ALFLQRLSTALSGLLLGFYRGWKLTLVILAVSPLIGIGAAVIGLSVAKFTELELKAYAKA 277 Query: 365 XXXXXXXFGAIRTVRAFAQEPHEISRYGGKVNETLKLGLKQAKVVGLFSG 514 +IRTV AF E E+ RY + + G+ + V+G F+G Sbjct: 278 GSIADEVLSSIRTVAAFGGENKEVERYEKNLMFAQRWGIWKGMVMGFFTG 327 Score = 57.8 bits (138), Expect = 2e-08 Identities = 41/178 (23%), Positives = 81/178 (45%), Gaps = 5/178 (2%) Frame = +2 Query: 5 LRAWLFNSASERVVARLRQDLFSHLINQEIAFFDVTRT--GELLSRLSEDTQIIKNAATT 178 L+ + F + E + RLR+ F ++ Q+I +FD + G L +RL+ D ++ A + Sbjct: 815 LQGYNFAKSGELLTKRLRKFGFKAMLRQDIGWFDDLKNNPGVLTTRLATDASQVQGATGS 874 Query: 179 NLSEALRNLTTTAIGLGFMFSTSWKLTLLALVIVPVISVAVRKFGRFLRELSHQTQXXXX 358 + + + T + + F +WKL+L+ V P ++++ + L + Q + Sbjct: 875 QVGMMVNSFTNIFVAVLIAFLFNWKLSLVISVFFPFLALSGAVQTKMLTGFASQDKEILE 934 Query: 359 XXXXXXXXXFGAIRTVRAFAQEPHEISRYGGKVNETLKLGLKQAKVVGL---FSGGLN 523 IRTV E I + ++ ++ K +++A V GL FS G++ Sbjct: 935 KAGQITNEALSNIRTVAGIGVEGRFIKAFEVELEKSYKTAIRKANVYGLCYAFSQGIS 992
>MDR3_MOUSE (P21447) Multidrug resistance protein 3 (EC 3.6.3.44)| (P-glycoprotein 3) (MDR1A) Length = 1276 Score = 83.6 bits (205), Expect = 3e-16 Identities = 48/162 (29%), Positives = 77/162 (47%) Frame = +2 Query: 29 ASERVVARLRQDLFSHLINQEIAFFDVTRTGELLSRLSEDTQIIKNAATTNLSEALRNLT 208 A+ R + ++RQ F ++NQEI +FDV GEL +RL++D I + + + Sbjct: 135 AAGRQIHKIRQKFFHAIMNQEIGWFDVHDVGELNTRLTDDVSKINEGIGDKIGMFFQAMA 194 Query: 209 TTAIGLGFMFSTSWKLTLLALVIVPVISVAVRKFGRFLRELSHQTQXXXXXXXXXXXXXF 388 T G F+ WKLTL+ L I PV+ ++ + + L + + Sbjct: 195 TFFGGFIIGFTRGWKLTLVILAISPVLGLSAGIWAKILSSFTDKELHAYAKAGAVAEEVL 254 Query: 389 GAIRTVRAFAQEPHEISRYGGKVNETLKLGLKQAKVVGLFSG 514 AIRTV AF + E+ RY + E +LG+K+A + G Sbjct: 255 AAIRTVIAFGGQKKELERYNNNLEEAKRLGIKKAITANISMG 296 Score = 65.5 bits (158), Expect = 9e-11 Identities = 43/169 (25%), Positives = 78/169 (46%), Gaps = 2/169 (1%) Frame = +2 Query: 5 LRAWLFNSASERVVARLRQDLFSHLINQEIAFFDVTR--TGELLSRLSEDTQIIKNAATT 178 L+ + F A E + RLR +F ++ Q++++FD + TG L +RL+ D +K A + Sbjct: 768 LQGFTFGKAGEILTKRLRYMVFKSMLRQDVSWFDDPKNTTGALTTRLANDAAQVKGATGS 827 Query: 179 NLSEALRNLTTTAIGLGFMFSTSWKLTLLALVIVPVISVAVRKFGRFLRELSHQTQXXXX 358 L+ +N+ G+ W+LTLL L IVP+I++A + L + + + Sbjct: 828 RLAVIFQNIANLGTGIIISLIYGWQLTLLLLAIVPIIAIAGVVEMKMLSGQALKDKKELE 887 Query: 359 XXXXXXXXXFGAIRTVRAFAQEPHEISRYGGKVNETLKLGLKQAKVVGL 505 RTV + +E + Y + + +K+A V G+ Sbjct: 888 GSGKIATEAIENFRTVVSLTREQKFETMYAQSLQIPYRNAMKKAHVFGI 936
>MDR1_CRIGR (P21448) Multidrug resistance protein 1 (EC 3.6.3.44)| (P-glycoprotein 1) (CD243 antigen) Length = 1276 Score = 83.6 bits (205), Expect = 3e-16 Identities = 48/162 (29%), Positives = 77/162 (47%) Frame = +2 Query: 29 ASERVVARLRQDLFSHLINQEIAFFDVTRTGELLSRLSEDTQIIKNAATTNLSEALRNLT 208 A+ R + ++RQ F ++NQEI +FDV GEL +RL++D I + + + Sbjct: 136 AAGRQIHKIRQKFFHAIMNQEIGWFDVHDVGELNTRLTDDVSKINEGIGDKIGMFFQAMA 195 Query: 209 TTAIGLGFMFSTSWKLTLLALVIVPVISVAVRKFGRFLRELSHQTQXXXXXXXXXXXXXF 388 T G F+ WKLTL+ L I PV+ ++ + + L + + Sbjct: 196 TFFGGFIIGFTRGWKLTLVILAISPVLGLSAGIWAKILSSFTDKELQAYAKAGAVAEEVL 255 Query: 389 GAIRTVRAFAQEPHEISRYGGKVNETLKLGLKQAKVVGLFSG 514 AIRTV AF + E+ RY + E +LG+K+A + G Sbjct: 256 AAIRTVIAFGGQKKELERYNNNLEEAKRLGIKKAITANISMG 297 Score = 65.1 bits (157), Expect = 1e-10 Identities = 44/169 (26%), Positives = 77/169 (45%), Gaps = 2/169 (1%) Frame = +2 Query: 5 LRAWLFNSASERVVARLRQDLFSHLINQEIAFFDVTR--TGELLSRLSEDTQIIKNAATT 178 L+ + F A E + RLR +F ++ Q++++FD + TG L +RL+ D +K A Sbjct: 769 LQGFTFGKAGEILTKRLRYMVFKSMLRQDVSWFDNPKNTTGALTTRLANDAGQVKGATGA 828 Query: 179 NLSEALRNLTTTAIGLGFMFSTSWKLTLLALVIVPVISVAVRKFGRFLRELSHQTQXXXX 358 L+ +N+ G+ W+LTLL L IVP+I++A + L + + + Sbjct: 829 RLAVITQNIANLGTGIIISLIYGWQLTLLLLAIVPIIAIAGVVEMKMLSGQALKDKKELE 888 Query: 359 XXXXXXXXXFGAIRTVRAFAQEPHEISRYGGKVNETLKLGLKQAKVVGL 505 RTV + +E + Y + + LK+A V G+ Sbjct: 889 GSGKIATEAIENFRTVVSLTREQKFENMYAQSLQIPYRNALKKAHVFGI 937
>MDR11_ARATH (Q9LJX0) Multidrug resistance protein 11 (P-glycoprotein 19)| Length = 1252 Score = 81.3 bits (199), Expect = 2e-15 Identities = 46/171 (26%), Positives = 86/171 (50%), Gaps = 1/171 (0%) Frame = +2 Query: 5 LRAWLFNSASERVVARLRQDLFSHLINQEIAFFDV-TRTGELLSRLSEDTQIIKNAATTN 181 + W+++ ER VA LR+ ++ Q++ FFD RTG+++ +S DT ++++A + Sbjct: 105 IACWMYSG--ERQVAALRKKYLEAVLKQDVGFFDTDARTGDIVFSVSTDTLLVQDAISEK 162 Query: 182 LSEALRNLTTTAIGLGFMFSTSWKLTLLALVIVPVISVAVRKFGRFLRELSHQTQXXXXX 361 + + L+T GL F ++WKL LL++ ++P I+ A + L ++ +++ Sbjct: 163 VGNFIHYLSTFLAGLVVGFVSAWKLALLSVAVIPGIAFAGGLYAYTLTGITSKSRESYAN 222 Query: 362 XXXXXXXXFGAIRTVRAFAQEPHEISRYGGKVNETLKLGLKQAKVVGLFSG 514 +RTV ++ E ++ Y + TLKLG K GL G Sbjct: 223 AGVIAEQAIAQVRTVYSYVGESKALNAYSDAIQYTLKLGYKAGMAKGLGLG 273 Score = 52.8 bits (125), Expect = 6e-07 Identities = 38/172 (22%), Positives = 74/172 (43%), Gaps = 2/172 (1%) Frame = +2 Query: 5 LRAWLFNSASERVVARLRQDLFSHLINQEIAFFDVTRTGELL--SRLSEDTQIIKNAATT 178 ++ + F+ E + R+R+ + S ++ E+ +FD L +RL+ D +K+A Sbjct: 747 IQHYFFSIMGENLTTRVRRMMLSAILRNEVGWFDEDEHNSSLIAARLATDAADVKSAIAE 806 Query: 179 NLSEALRNLTTTAIGLGFMFSTSWKLTLLALVIVPVISVAVRKFGRFLRELSHQTQXXXX 358 +S L+N+T+ F W+++LL L P++ +A L+ + T Sbjct: 807 RISVILQNMTSLLTSFIVAFIVEWRVSLLILGTFPLLVLANFAQQLSLKGFAGDTAKAHA 866 Query: 359 XXXXXXXXXFGAIRTVRAFAQEPHEISRYGGKVNETLKLGLKQAKVVGLFSG 514 IRTV AF + +S + ++ K L +++ G G Sbjct: 867 KTSMIAGEGVSNIRTVAAFNAQSKILSLFCHELRVPQKRSLYRSQTSGFLFG 918
>MDR4_ARATH (O80725) Multidrug resistance protein 4 (P-glycoprotein 4)| Length = 1286 Score = 80.9 bits (198), Expect = 2e-15 Identities = 52/173 (30%), Positives = 83/173 (47%), Gaps = 1/173 (0%) Frame = +2 Query: 5 LRAWLFNSASERVVARLRQDLFSHLINQEIAFFDV-TRTGELLSRLSEDTQIIKNAATTN 181 L W+ + ER AR+R ++ Q+IAFFD+ T TGE++ R+S DT +I++A Sbjct: 124 LSGWMISG--ERQAARIRSLYLKTILRQDIAFFDIDTNTGEVVGRMSGDTVLIQDAMGEK 181 Query: 182 LSEALRNLTTTAIGLGFMFSTSWKLTLLALVIVPVISVAVRKFGRFLRELSHQTQXXXXX 361 + +A++ L T G F W LTL+ L +P++ +A + + + + Q Sbjct: 182 VGKAIQLLATFVGGFVIAFVRGWLLTLVMLSSIPLLVMAGALLAIVIAKTASRGQTAYAK 241 Query: 362 XXXXXXXXFGAIRTVRAFAQEPHEISRYGGKVNETLKLGLKQAKVVGLFSGGL 520 G+IRTV +F E IS Y + K G+ + GL G L Sbjct: 242 AATVVEQTIGSIRTVASFTGEKQAISNYNKHLVTAYKAGVIEGGSTGLGLGTL 294 Score = 73.2 bits (178), Expect = 5e-13 Identities = 43/171 (25%), Positives = 84/171 (49%), Gaps = 2/171 (1%) Frame = +2 Query: 8 RAWLFNSASERVVARLRQDLFSHLINQEIAFFDVTR--TGELLSRLSEDTQIIKNAATTN 181 + + F A ++V R+R F +++ E+ +FD +G + +RLS D I+ + Sbjct: 780 QTFFFAIAGCKLVQRIRSMCFEKVVHMEVGWFDEPENSSGTIGARLSADAATIRGLVGDS 839 Query: 182 LSEALRNLTTTAIGLGFMFSTSWKLTLLALVIVPVISVAVRKFGRFLRELSHQTQXXXXX 361 L++ ++NL++ GL F W+L + L ++P+I++ + +F++ S + Sbjct: 840 LAQTVQNLSSILAGLIIAFLACWQLAFVVLAMLPLIALNGFLYMKFMKGFSADAKKMYGE 899 Query: 362 XXXXXXXXFGAIRTVRAFAQEPHEISRYGGKVNETLKLGLKQAKVVGLFSG 514 G+IRTV +F E ++ Y K +K G++Q V G+ G Sbjct: 900 ASQVANDAVGSIRTVASFCAEDKVMNMYSKKCEGPMKNGIRQGIVSGIGFG 950
>TAP2_RAT (P36372) Antigen peptide transporter 2 (APT2)| Length = 703 Score = 80.9 bits (198), Expect = 2e-15 Identities = 48/146 (32%), Positives = 74/146 (50%) Frame = +2 Query: 8 RAWLFNSASERVVARLRQDLFSHLINQEIAFFDVTRTGELLSRLSEDTQIIKNAATTNLS 187 R F A R+ R+R+ LFS L+ Q++AFF T+TGEL SRLS DT ++ + N + Sbjct: 210 RGGSFLFAESRINLRIREQLFSSLLRQDLAFFQETKTGELNSRLSSDTSLMSQWLSLNAN 269 Query: 188 EALRNLTTTAIGLGFMFSTSWKLTLLALVIVPVISVAVRKFGRFLRELSHQTQXXXXXXX 367 LR+L FM S +LT L+L+ +P+ A + + + + + Q Sbjct: 270 ILLRSLVKVVGLYYFMLQVSPRLTFLSLLDLPLTIAAEKVYNPRHQAVLKEIQDAVAKAG 329 Query: 368 XXXXXXFGAIRTVRAFAQEPHEISRY 445 G ++TVR+F E E+ RY Sbjct: 330 QVVREAVGGLQTVRSFGAEEQEVRRY 355
>MDR1_HUMAN (P08183) Multidrug resistance protein 1 (EC 3.6.3.44)| (P-glycoprotein 1) (CD243 antigen) Length = 1280 Score = 80.9 bits (198), Expect = 2e-15 Identities = 45/162 (27%), Positives = 77/162 (47%) Frame = +2 Query: 29 ASERVVARLRQDLFSHLINQEIAFFDVTRTGELLSRLSEDTQIIKNAATTNLSEALRNLT 208 A+ R + ++R+ F ++ QEI +FDV GEL +RL++D I + +++ Sbjct: 139 AAGRQIHKIRKQFFHAIMRQEIGWFDVHDVGELNTRLTDDVSKINEGIGDKIGMFFQSMA 198 Query: 209 TTAIGLGFMFSTSWKLTLLALVIVPVISVAVRKFGRFLRELSHQTQXXXXXXXXXXXXXF 388 T G F+ WKLTL+ L I PV+ ++ + + L + + Sbjct: 199 TFFTGFIVGFTRGWKLTLVILAISPVLGLSAAVWAKILSSFTDKELLAYAKAGAVAEEVL 258 Query: 389 GAIRTVRAFAQEPHEISRYGGKVNETLKLGLKQAKVVGLFSG 514 AIRTV AF + E+ RY + E ++G+K+A + G Sbjct: 259 AAIRTVIAFGGQKKELERYNKNLEEAKRIGIKKAITANISIG 300 Score = 67.0 bits (162), Expect = 3e-11 Identities = 44/169 (26%), Positives = 78/169 (46%), Gaps = 2/169 (1%) Frame = +2 Query: 5 LRAWLFNSASERVVARLRQDLFSHLINQEIAFFDVTR--TGELLSRLSEDTQIIKNAATT 178 L+ + F A E + RLR +F ++ Q++++FD + TG L +RL+ D +K A + Sbjct: 772 LQGFTFGKAGEILTKRLRYMVFRSMLRQDVSWFDDPKNTTGALTTRLANDAAQVKGAIGS 831 Query: 179 NLSEALRNLTTTAIGLGFMFSTSWKLTLLALVIVPVISVAVRKFGRFLRELSHQTQXXXX 358 L+ +N+ G+ F W+LTLL L IVP+I++A + L + + + Sbjct: 832 RLAVITQNIANLGTGIIISFIYGWQLTLLLLAIVPIIAIAGVVEMKMLSGQALKDKKELE 891 Query: 359 XXXXXXXXXFGAIRTVRAFAQEPHEISRYGGKVNETLKLGLKQAKVVGL 505 RTV + QE Y + + L++A + G+ Sbjct: 892 GAGKIATEAIENFRTVVSLTQEQKFEHMYAQSLQVPYRNSLRKAHIFGI 940
>MDR5_ARATH (Q9SYI3) Putative multidrug resistance protein 5 (P-glycoprotein 5)| Length = 1230 Score = 80.5 bits (197), Expect = 3e-15 Identities = 45/169 (26%), Positives = 85/169 (50%), Gaps = 2/169 (1%) Frame = +2 Query: 14 WLFNSASERVVARLRQDLFSHLINQEIAFFDV--TRTGELLSRLSEDTQIIKNAATTNLS 187 +LF A R++ R+R F +++ E+ +FD +G + +RLS D +I+ +L Sbjct: 725 YLFAIAGGRLIRRIRSMCFEKVVHMEVGWFDEPGNSSGAMGARLSADAALIRTLVGDSLC 784 Query: 188 EALRNLTTTAIGLGFMFSTSWKLTLLALVIVPVISVAVRKFGRFLRELSHQTQXXXXXXX 367 +++N+ + GL F+ SW++ ++ LVI+P I + +F++ S + Sbjct: 785 LSVKNVASLVTGLIIAFTASWEVAIIILVIIPFIGINGYIQIKFMKGFSADAKAKYEEAS 844 Query: 368 XXXXXXFGAIRTVRAFAQEPHEISRYGGKVNETLKLGLKQAKVVGLFSG 514 G+IRTV +F E + Y + +T+K G+KQ + G+ G Sbjct: 845 QVANDAVGSIRTVASFCAEEKVMEMYKKRCEDTIKSGIKQGLISGVGFG 893 Score = 78.6 bits (192), Expect = 1e-14 Identities = 49/161 (30%), Positives = 77/161 (47%), Gaps = 1/161 (0%) Frame = +2 Query: 35 ERVVARLRQDLFSHLINQEIAFFDV-TRTGELLSRLSEDTQIIKNAATTNLSEALRNLTT 211 ER AR+R ++ Q+I FFDV TGE++ R+S DT +I +A + + ++ ++T Sbjct: 101 ERQAARIRSLYLKTILRQDIGFFDVEMTTGEVVGRMSGDTVLILDAMGEKVGKFIQLIST 160 Query: 212 TAIGLGFMFSTSWKLTLLALVIVPVISVAVRKFGRFLRELSHQTQXXXXXXXXXXXXXFG 391 G F W LTL+ L +P+++++ + S Q Q G Sbjct: 161 FVGGFVIAFLRGWLLTLVMLTSIPLLAMSGAAIAIIVTRASSQEQAAYAKASNVVEQTLG 220 Query: 392 AIRTVRAFAQEPHEISRYGGKVNETLKLGLKQAKVVGLFSG 514 +IRTV +F E +S Y +N K +KQ V GL G Sbjct: 221 SIRTVASFTGEKQAMSSYKELINLAYKSNVKQGFVTGLGLG 261
>MDR2_CRIGR (P21449) Multidrug resistance protein 2 (EC 3.6.3.44)| (P-glycoprotein 2) Length = 1276 Score = 80.1 bits (196), Expect = 4e-15 Identities = 45/162 (27%), Positives = 78/162 (48%) Frame = +2 Query: 29 ASERVVARLRQDLFSHLINQEIAFFDVTRTGELLSRLSEDTQIIKNAATTNLSEALRNLT 208 A+ R + ++RQ F ++NQEI +FDV GEL +RL++D I + + +++ Sbjct: 138 AAGRQINKIRQKFFHAIMNQEIGWFDVHDIGELNTRLTDDVSKINDGIGDKIGMFFQSIA 197 Query: 209 TTAIGLGFMFSTSWKLTLLALVIVPVISVAVRKFGRFLRELSHQTQXXXXXXXXXXXXXF 388 T F + WKLTL+ L + P+I ++ + + L +++ Sbjct: 198 TFLAAFIVGFISGWKLTLVILAVSPLIGLSSAMWAKVLTSFTNKELQAYAKAGAVAEEVL 257 Query: 389 GAIRTVRAFAQEPHEISRYGGKVNETLKLGLKQAKVVGLFSG 514 AIRTV AF + E+ RY + E +G+K+A + G Sbjct: 258 AAIRTVIAFGGQNKELERYNKNLEEAKNVGIKKAVTANISIG 299 Score = 61.6 bits (148), Expect = 1e-09 Identities = 43/168 (25%), Positives = 77/168 (45%), Gaps = 2/168 (1%) Frame = +2 Query: 8 RAWLFNSASERVVARLRQDLFSHLINQEIAFFDVTR--TGELLSRLSEDTQIIKNAATTN 181 + + F A E + RLR +F ++ Q+I++FD R TG L +RL+ D +K A ++ Sbjct: 771 QGFTFGKAGEILTKRLRYMVFKSMLRQDISWFDDHRNSTGALTTRLASDAANVKGAMSSR 830 Query: 182 LSEALRNLTTTAIGLGFMFSTSWKLTLLALVIVPVISVAVRKFGRFLRELSHQTQXXXXX 361 L+ +N+ G+ W+LTLL +VI P+I ++ + L + + + Sbjct: 831 LAGITQNVANLGTGIIISLVYGWQLTLLLVVIAPLIILSGMMEMKVLSGQALKDKKELEV 890 Query: 362 XXXXXXXXFGAIRTVRAFAQEPHEISRYGGKVNETLKLGLKQAKVVGL 505 RTV + +E + Y + + LK+A V G+ Sbjct: 891 SGKIATEAIENFRTVVSLTREQKFENMYAQSLQIPYRNALKKAHVFGI 938
>MDR8_ARATH (Q9FWX7) Multidrug resistance protein 8 (P-glycoprotein 11)| Length = 1278 Score = 79.7 bits (195), Expect = 5e-15 Identities = 49/169 (28%), Positives = 86/169 (50%), Gaps = 2/169 (1%) Frame = +2 Query: 14 WLFNSASERVVARLRQDLFSHLINQEIAFFDVTR--TGELLSRLSEDTQIIKNAATTNLS 187 +LF A +++ R+R F ++ E+A+FD + +G + +RLS D +I+ LS Sbjct: 772 YLFAVAGGKLIRRIRSMCFEKAVHMEVAWFDEPQNSSGTMGARLSADATLIRALVGDALS 831 Query: 188 EALRNLTTTAIGLGFMFSTSWKLTLLALVIVPVISVAVRKFGRFLRELSHQTQXXXXXXX 367 A++N+ + A GL F+ SW+L L+ LV++P+I + +F++ S + Sbjct: 832 LAVQNVASAASGLIIAFTASWELALIILVMLPLIGINGFVQVKFMKGFSADAKSKYEEAS 891 Query: 368 XXXXXXFGAIRTVRAFAQEPHEISRYGGKVNETLKLGLKQAKVVGLFSG 514 G+IRTV +F E + Y + +K G+KQ + GL G Sbjct: 892 QVANDAVGSIRTVASFCAEEKVMQMYKKQCEGPIKDGIKQGFISGLGFG 940 Score = 78.2 bits (191), Expect = 1e-14 Identities = 47/161 (29%), Positives = 77/161 (47%), Gaps = 1/161 (0%) Frame = +2 Query: 35 ERVVARLRQDLFSHLINQEIAFFDV-TRTGELLSRLSEDTQIIKNAATTNLSEALRNLTT 211 ER AR+R ++ Q+I FFDV T TGE++ R+S DT +I++A + + ++ ++T Sbjct: 129 ERQAARIRSTYLKTILRQDIGFFDVETNTGEVVGRMSGDTVLIQDAMGEKVGKFIQLVST 188 Query: 212 TAIGLGFMFSTSWKLTLLALVIVPVISVAVRKFGRFLRELSHQTQXXXXXXXXXXXXXFG 391 G F W LTL+ L +P++++A + S + Q G Sbjct: 189 FVGGFVLAFIKGWLLTLVMLTSIPLLAMAGAAMALIVTRASSRGQAAYAKAATVVEQTIG 248 Query: 392 AIRTVRAFAQEPHEISRYGGKVNETLKLGLKQAKVVGLFSG 514 +IRTV +F E I+ Y + K ++Q GL G Sbjct: 249 SIRTVASFTGEKQAINSYKKFITSAYKSSIQQGFSTGLGLG 289
>MSBA_SHEON (Q8EDF0) Lipid A export ATP-binding/permease protein msbA| Length = 601 Score = 79.0 bits (193), Expect = 8e-15 Identities = 48/158 (30%), Positives = 80/158 (50%), Gaps = 5/158 (3%) Frame = +2 Query: 32 SERVVARLRQDLFSHLINQEIAFFDVTRTGELLSRLSEDTQIIKNAATTNLSEALRNLTT 211 S R++ +RQ +F H ++ +++ D TG L+S+++ DT+ I A+ + L +R+ T Sbjct: 111 SARLIMDMRQQVFEHYLSLPVSYMDKENTGNLISKVTFDTEQIARASGSALISIVRDSVT 170 Query: 212 TAIGLGFMFSTSWKLTLLALVIVPVISVAVRKFGRFLRELSHQTQXXXXXXXXXXXXXFG 391 LG MF SWKL+L LVI P++ V + R R++S Q Q Sbjct: 171 IIGMLGLMFYNSWKLSLCILVIGPIMGVVITIVSRRFRKVSKQIQTAMGDVSAATEQMIK 230 Query: 392 AIRTVRAFAQEPHEISRYGGKVN-----ETLKLGLKQA 490 + V AF + E +R+ K+N + +KL + QA Sbjct: 231 GHKNVLAFGGQETETARF-AKINDRNRHQNMKLAVAQA 267
>MDR17_ARATH (Q9M1Q9) Multidrug resistance protein 17 (P-glycoprotein 21)| Length = 1292 Score = 79.0 bits (193), Expect = 8e-15 Identities = 47/166 (28%), Positives = 83/166 (50%), Gaps = 1/166 (0%) Frame = +2 Query: 29 ASERVVARLRQDLFSHLINQEIAFFDV-TRTGELLSRLSEDTQIIKNAATTNLSEALRNL 205 + ER R+R ++ Q+IAFFDV T TGE++ R+S DT +I++A + +A++ + Sbjct: 149 SGERQAGRIRSLYLQTILRQDIAFFDVETNTGEVVGRMSGDTVLIQDAMGEKVGKAIQLV 208 Query: 206 TTTAIGLGFMFSTSWKLTLLALVIVPVISVAVRKFGRFLRELSHQTQXXXXXXXXXXXXX 385 +T G F+ W LTL+ + +P++ ++ + +++ + Q Sbjct: 209 STFIGGFVIAFTEGWLLTLVMVSSIPLLVMSGAALAIVISKMASRGQTSYAKAAVVVEQT 268 Query: 386 FGAIRTVRAFAQEPHEISRYGGKVNETLKLGLKQAKVVGLFSGGLN 523 G+IRTV +F E IS Y + + G+ + GL G LN Sbjct: 269 VGSIRTVASFTGEKQAISNYNKHLVSAYRAGVFEGASTGLGLGTLN 314 Score = 68.9 bits (167), Expect = 8e-12 Identities = 43/167 (25%), Positives = 79/167 (47%), Gaps = 2/167 (1%) Frame = +2 Query: 20 FNSASERVVARLRQDLFSHLINQEIAFFDVTR--TGELLSRLSEDTQIIKNAATTNLSEA 193 F+ A ++V R+R F ++ E+ +FD T +G + +RLS D ++ L++ Sbjct: 794 FSIAGCKLVQRIRSMCFEKVVRMEVGWFDETENSSGAIGARLSADAATVRGLVGDALAQT 853 Query: 194 LRNLTTTAIGLGFMFSTSWKLTLLALVIVPVISVAVRKFGRFLRELSHQTQXXXXXXXXX 373 ++NL + GL F SW+L + L ++P+I + + +F+ S + Sbjct: 854 VQNLASVTAGLVIAFVASWQLAFIVLAMLPLIGLNGYIYMKFMVGFSADAK----EASQV 909 Query: 374 XXXXFGAIRTVRAFAQEPHEISRYGGKVNETLKLGLKQAKVVGLFSG 514 G+IRTV +F E + Y K ++ G++Q V G+ G Sbjct: 910 ANDAVGSIRTVASFCAEEKVMKMYKKKCEGPMRTGIRQGIVSGIGFG 956
>MSBA_CHRVO (Q7NZU6) Lipid A export ATP-binding/permease protein msbA| Length = 584 Score = 79.0 bits (193), Expect = 8e-15 Identities = 40/151 (26%), Positives = 77/151 (50%) Frame = +2 Query: 38 RVVARLRQDLFSHLINQEIAFFDVTRTGELLSRLSEDTQIIKNAATTNLSEALRNLTTTA 217 ++V RLRQ +F+ L+N ++D ++G L+SR++ D + A ++ +R+ T Sbjct: 94 QLVQRLRQQMFAKLVNLPARYYDEHQSGRLMSRITNDVNQVTEAGFNVITVTVRDGLTAL 153 Query: 218 IGLGFMFSTSWKLTLLALVIVPVISVAVRKFGRFLRELSHQTQXXXXXXXXXXXXXFGAI 397 LG M +T W+LTL+ LV++P ++ +R G+ LR L+ Q Q Sbjct: 154 GMLGLMLTTDWQLTLICLVVMPAVTYCMRLVGQRLRGLARQNQQHMAQMTQVLAESIQCQ 213 Query: 398 RTVRAFAQEPHEISRYGGKVNETLKLGLKQA 490 R ++ + + E++R+ + +KQ+ Sbjct: 214 RAIKVYGGQEREMARFDHTATSVRRNQVKQS 244
>TAP1_HUMAN (Q03518) Antigen peptide transporter 1 (APT1) (Peptide transporter| TAP1) (ATP-binding cassette sub-family B member 2) (Peptide transporter PSF1) (Peptide supply factor 1) (PSF-1) (Peptide transporter involved in antigen processing 1) Length = 748 Score = 79.0 bits (193), Expect = 8e-15 Identities = 45/158 (28%), Positives = 81/158 (51%) Frame = +2 Query: 17 LFNSASERVVARLRQDLFSHLINQEIAFFDVTRTGELLSRLSEDTQIIKNAATTNLSEAL 196 ++N+ V + L+ ++F ++ QE FF +TG ++SR++EDT + ++ + NLS L Sbjct: 248 IYNNTMGHVHSHLQGEVFGAVLRQETEFFQQNQTGNIMSRVTEDTSTLSDSLSENLSLFL 307 Query: 197 RNLTTTAIGLGFMFSTSWKLTLLALVIVPVISVAVRKFGRFLRELSHQTQXXXXXXXXXX 376 L LG M S LT++ L+ +P++ + +K G++ + L Q + Sbjct: 308 WYLVRGLCLLGIMLWGSVSLTMVTLITLPLLFLLPKKVGKWYQLLEVQVRESLAKSSQVA 367 Query: 377 XXXFGAIRTVRAFAQEPHEISRYGGKVNETLKLGLKQA 490 A+ TVR+FA E E ++ K+ E L K+A Sbjct: 368 IEALSAMPTVRSFANEEGEAQKFREKLQEIKTLNQKEA 405
>ABCBB_HUMAN (O95342) Bile salt export pump (ATP-binding cassette sub-family B| member 11) Length = 1321 Score = 78.2 bits (191), Expect = 1e-14 Identities = 42/162 (25%), Positives = 77/162 (47%) Frame = +2 Query: 29 ASERVVARLRQDLFSHLINQEIAFFDVTRTGELLSRLSEDTQIIKNAATTNLSEALRNLT 208 A+ R + ++R+ F ++ EI +FD GEL +R S+D I +A ++ ++ +T Sbjct: 166 AAARQIQKMRKFYFRRIMRMEIGWFDCNSVGELNTRFSDDINKINDAIADQMALFIQRMT 225 Query: 209 TTAIGLGFMFSTSWKLTLLALVIVPVISVAVRKFGRFLRELSHQTQXXXXXXXXXXXXXF 388 +T G F WKLTL+ + + P+I + G + + + Sbjct: 226 STICGFLLGFFRGWKLTLVIISVSPLIGIGAATIGLSVSKFTDYELKAYAKAGVVADEVI 285 Query: 389 GAIRTVRAFAQEPHEISRYGGKVNETLKLGLKQAKVVGLFSG 514 ++RTV AF E E+ RY + + G+++ V+G F+G Sbjct: 286 SSMRTVAAFGGEKREVERYEKNLVFAQRWGIRKGIVMGFFTG 327 Score = 64.7 bits (156), Expect = 2e-10 Identities = 41/168 (24%), Positives = 77/168 (45%), Gaps = 2/168 (1%) Frame = +2 Query: 5 LRAWLFNSASERVVARLRQDLFSHLINQEIAFFDVTRT--GELLSRLSEDTQIIKNAATT 178 L+ + F + E + RLR+ F ++ Q+IA+FD R G L +RL+ D ++ AA + Sbjct: 815 LQGYAFAKSGELLTKRLRKFGFRAMLGQDIAWFDDLRNSPGALTTRLATDASQVQGAAGS 874 Query: 179 NLSEALRNLTTTAIGLGFMFSTSWKLTLLALVIVPVISVAVRKFGRFLRELSHQTQXXXX 358 + + + T + + FS SWKL+L+ L P ++++ R L + + + Sbjct: 875 QIGMIVNSFTNVTVAMIIAFSFSWKLSLVILCFFPFLALSGATQTRMLTGFASRDKQALE 934 Query: 359 XXXXXXXXXFGAIRTVRAFAQEPHEISRYGGKVNETLKLGLKQAKVVG 502 IRTV +E I ++ + K +++A + G Sbjct: 935 MVGQITNEALSNIRTVAGIGKERRFIEALETELEKPFKTAIQKANIYG 982
>TAP1_GORGO (Q28433) Antigen peptide transporter 1 (APT1) (Peptide transporter| TAP1) (ATP-binding cassette sub-family B member 2) Length = 748 Score = 78.2 bits (191), Expect = 1e-14 Identities = 46/158 (29%), Positives = 80/158 (50%) Frame = +2 Query: 17 LFNSASERVVARLRQDLFSHLINQEIAFFDVTRTGELLSRLSEDTQIIKNAATTNLSEAL 196 ++N+ V + L+ ++F ++ QE FF +TG + SR++EDT + ++ + NLS L Sbjct: 248 IYNNTMGHVHSHLQGEVFGAVLRQETEFFQQNQTGNITSRVTEDTSTLSDSLSENLSLFL 307 Query: 197 RNLTTTAIGLGFMFSTSWKLTLLALVIVPVISVAVRKFGRFLRELSHQTQXXXXXXXXXX 376 L LG M S LT++ LV +P++ + +K G++ + L Q + Sbjct: 308 WYLVRGLCLLGIMLWGSVSLTMVTLVTLPLLFLLPKKVGKWYQLLEVQVRESLAKSSQVA 367 Query: 377 XXXFGAIRTVRAFAQEPHEISRYGGKVNETLKLGLKQA 490 A+ TVR+FA E E ++ K+ E L K+A Sbjct: 368 IEALSAMPTVRSFANEEGEAQKFREKLQEIKTLNQKEA 405
>MDR3_CRIGR (P23174) Multidrug resistance protein 3 (EC 3.6.3.44)| (P-glycoprotein 3) Length = 1281 Score = 77.8 bits (190), Expect = 2e-14 Identities = 43/154 (27%), Positives = 74/154 (48%) Frame = +2 Query: 29 ASERVVARLRQDLFSHLINQEIAFFDVTRTGELLSRLSEDTQIIKNAATTNLSEALRNLT 208 A+ R + ++RQ+ F ++ QE+ +FD+ T EL +RL++D I + + + Sbjct: 141 AAGRQIKKIRQNFFHAILRQEMGWFDIKGTTELNTRLTDDISKISEGIGDKVGMFFQAVA 200 Query: 209 TTAIGLGFMFSTSWKLTLLALVIVPVISVAVRKFGRFLRELSHQTQXXXXXXXXXXXXXF 388 T G F WKLTL+ + I P++ ++ + + L S + Sbjct: 201 TFFAGFIVGFIRGWKLTLVIMAISPILGLSAAVWAKILSTFSDKELAAYAKAGAVAEEAL 260 Query: 389 GAIRTVRAFAQEPHEISRYGGKVNETLKLGLKQA 490 GAIRTV AF + E+ RY + K+G+K+A Sbjct: 261 GAIRTVIAFGGQNKELERYQKHLENAKKIGIKKA 294 Score = 66.2 bits (160), Expect = 6e-11 Identities = 46/169 (27%), Positives = 79/169 (46%), Gaps = 2/169 (1%) Frame = +2 Query: 5 LRAWLFNSASERVVARLRQDLFSHLINQEIAFFDVTR--TGELLSRLSEDTQIIKNAATT 178 L+ + F A E + RLR F ++ Q++++FD + TG L +RL+ D ++ A T Sbjct: 773 LQGFTFGKAGEILTTRLRSMAFKAMLRQDMSWFDDYKNSTGALSTRLATDRAQVQGATGT 832 Query: 179 NLSEALRNLTTTAIGLGFMFSTSWKLTLLALVIVPVISVAVRKFGRFLRELSHQTQXXXX 358 L+ +N G+ F W+LTLL L +VP I+V+ + L + + + Sbjct: 833 RLALIAQNTANLGTGIIISFIYGWQLTLLLLSVVPFIAVSGIVEMKMLAGNAKRDKKALE 892 Query: 359 XXXXXXXXXFGAIRTVRAFAQEPHEISRYGGKVNETLKLGLKQAKVVGL 505 IRTV + QE S Y K++E + ++ A + G+ Sbjct: 893 AAGKIATEAIENIRTVVSLTQERKFESMYVEKLHEPYRNSVQMAHIYGI 941
>MSBA_MANSM (Q65U21) Lipid A export ATP-binding/permease protein msbA| Length = 585 Score = 77.8 bits (190), Expect = 2e-14 Identities = 46/158 (29%), Positives = 78/158 (49%) Frame = +2 Query: 11 AWLFNSASERVVARLRQDLFSHLINQEIAFFDVTRTGELLSRLSEDTQIIKNAATTNLSE 190 AW+ S +VV +R+ LF HL+ ++FFD TG LLSR++ D++ + N+++ L Sbjct: 92 AWV----SGKVVMTMRRRLFKHLMYMPVSFFDQNSTGRLLSRITYDSEQVANSSSNALVT 147 Query: 191 ALRNLTTTAIGLGFMFSTSWKLTLLALVIVPVISVAVRKFGRFLRELSHQTQXXXXXXXX 370 +R L M +TSW+L+++ +I PVI+V +R + R LS Q Sbjct: 148 IVREGAYIISLLAVMIATSWQLSVVLFIIGPVIAVLIRLVSKIFRRLSKNMQNSMGELTA 207 Query: 371 XXXXXFGAIRTVRAFAQEPHEISRYGGKVNETLKLGLK 484 + V +F + E R+ N+ + G+K Sbjct: 208 TAEQMLKGHKVVLSFGGQQIEEQRFNEVSNDMRRKGMK 245
>MDR3_HUMAN (P21439) Multidrug resistance protein 3 (EC 3.6.3.44)| (P-glycoprotein 3) Length = 1279 Score = 77.0 bits (188), Expect = 3e-14 Identities = 43/154 (27%), Positives = 73/154 (47%) Frame = +2 Query: 29 ASERVVARLRQDLFSHLINQEIAFFDVTRTGELLSRLSEDTQIIKNAATTNLSEALRNLT 208 A+ R + ++RQ F ++ QEI +FD+ T EL +RL++D I + + + Sbjct: 141 AAGRQIRKIRQKFFHAILRQEIGWFDINDTTELNTRLTDDISKISEGIGDKVGMFFQAVA 200 Query: 209 TTAIGLGFMFSTSWKLTLLALVIVPVISVAVRKFGRFLRELSHQTQXXXXXXXXXXXXXF 388 T G F WKLTL+ + I P++ ++ + + L S + Sbjct: 201 TFFAGFIVGFIRGWKLTLVIMAISPILGLSAAVWAKILSAFSDKELAAYAKAGAVAEEAL 260 Query: 389 GAIRTVRAFAQEPHEISRYGGKVNETLKLGLKQA 490 GAIRTV AF + E+ RY + ++G+K+A Sbjct: 261 GAIRTVIAFGGQNKELERYQKHLENAKEIGIKKA 294 Score = 65.9 bits (159), Expect = 7e-11 Identities = 45/169 (26%), Positives = 80/169 (47%), Gaps = 2/169 (1%) Frame = +2 Query: 5 LRAWLFNSASERVVARLRQDLFSHLINQEIAFFDVTR--TGELLSRLSEDTQIIKNAATT 178 L+ + F A E + RLR F ++ Q++++FD + TG L +RL+ D ++ A T Sbjct: 771 LQGFTFGKAGEILTRRLRSMAFKAMLRQDMSWFDDHKNSTGALSTRLATDAAQVQGATGT 830 Query: 179 NLSEALRNLTTTAIGLGFMFSTSWKLTLLALVIVPVISVAVRKFGRFLRELSHQTQXXXX 358 L+ +N+ G+ F W+LTLL L +VP+I+V+ + L + + + Sbjct: 831 RLALIAQNIANLGTGIIISFIYGWQLTLLLLAVVPIIAVSGIVEMKLLAGNAKRDKKELE 890 Query: 359 XXXXXXXXXFGAIRTVRAFAQEPHEISRYGGKVNETLKLGLKQAKVVGL 505 IRTV + QE S Y K+ + +++A + G+ Sbjct: 891 AAGKIATEAIENIRTVVSLTQERKFESMYVEKLYGPYRNSVQKAHIYGI 939
>LMRA_LACLA (Q9CHL8) Multidrug resistance ABC transporter ATP-binding and| permease protein (EC 3.6.3.44) Length = 590 Score = 77.0 bits (188), Expect = 3e-14 Identities = 45/170 (26%), Positives = 78/170 (45%) Frame = +2 Query: 2 ALRAWLFNSASERVVARLRQDLFSHLINQEIAFFDVTRTGELLSRLSEDTQIIKNAATTN 181 A+ A + E VV LR ++ +I+ + +FD +TGE+ SRL+ DT +KN + Sbjct: 90 AIAAIVLGIFGESVVKNLRTRVWDKMIHLPVKYFDEVKTGEMSSRLANDTTQVKNLIANS 149 Query: 182 LSEALRNLTTTAIGLGFMFSTSWKLTLLALVIVPVISVAVRKFGRFLRELSHQTQXXXXX 361 + +A ++ + FM W+LTL ++ VPV+ + + F +++ Q Sbjct: 150 IPQAFTSILLLVGSIVFMLQMQWRLTLAMIIAVPVVMLIMFPIMTFGQKIGRTRQDSLAN 209 Query: 362 XXXXXXXXFGAIRTVRAFAQEPHEISRYGGKVNETLKLGLKQAKVVGLFS 511 IR V++ E + VN K+G+K+A GL S Sbjct: 210 FQGIASESLSEIRLVKSSNAEKQASKKAENDVNALYKIGVKEAIFDGLMS 259
>TAP2_MOUSE (P36371) Antigen peptide transporter 2 (APT2) (Histocompatibility| antigen modifier 2) Length = 702 Score = 76.3 bits (186), Expect = 5e-14 Identities = 46/146 (31%), Positives = 71/146 (48%) Frame = +2 Query: 8 RAWLFNSASERVVARLRQDLFSHLINQEIAFFDVTRTGELLSRLSEDTQIIKNAATTNLS 187 R F R+ R+R+ LFS L+ Q++ FF T+TGEL SRLS DT ++ N + Sbjct: 209 RGGSFLFTMSRINLRIREQLFSSLLRQDLGFFQETKTGELNSRLSSDTSLMSRWLPFNAN 268 Query: 188 EALRNLTTTAIGLGFMFSTSWKLTLLALVIVPVISVAVRKFGRFLRELSHQTQXXXXXXX 367 LR+L FM S +LT L+L+ +P+ A + + + + + Q Sbjct: 269 ILLRSLVKVVGLYFFMLQVSPRLTFLSLLDLPLTIAAEKVYNPRHQAVLKEIQDAVAKAG 328 Query: 368 XXXXXXFGAIRTVRAFAQEPHEISRY 445 G ++TVR+F E E+S Y Sbjct: 329 QVVREAVGGLQTVRSFGAEEQEVSHY 354
>MDR16_ARATH (Q9FWX8) Multidrug resistance protein 16 (P-glycoprotein 12)| Length = 1229 Score = 76.3 bits (186), Expect = 5e-14 Identities = 47/169 (27%), Positives = 84/169 (49%), Gaps = 2/169 (1%) Frame = +2 Query: 14 WLFNSASERVVARLRQDLFSHLINQEIAFFDVTR--TGELLSRLSEDTQIIKNAATTNLS 187 +LF A +++ R++ F ++ E+++FD +G + +RLS D +I+ LS Sbjct: 723 YLFAVAGGKLIRRIQSMCFEKAVHMEVSWFDEPENSSGTMGARLSTDAALIRALVGDALS 782 Query: 188 EALRNLTTTAIGLGFMFSTSWKLTLLALVIVPVISVAVRKFGRFLRELSHQTQXXXXXXX 367 A++N + A GL F+ SW+L L+ LV++P+I + +F++ S + Sbjct: 783 LAVQNAASAASGLIIAFTASWELALIILVMLPLIGINGFLQVKFMKGFSADAKSKYEEAS 842 Query: 368 XXXXXXFGAIRTVRAFAQEPHEISRYGGKVNETLKLGLKQAKVVGLFSG 514 G+IRTV +F E + Y + +K G+KQ + GL G Sbjct: 843 QVANDAVGSIRTVASFCAEEKVMQMYNKQCEGPIKDGVKQGFISGLGFG 891
>MDR2_MOUSE (P21440) Multidrug resistance protein 2 (EC 3.6.3.44)| (P-glycoprotein 2) Length = 1276 Score = 76.3 bits (186), Expect = 5e-14 Identities = 43/154 (27%), Positives = 73/154 (47%) Frame = +2 Query: 29 ASERVVARLRQDLFSHLINQEIAFFDVTRTGELLSRLSEDTQIIKNAATTNLSEALRNLT 208 A+ R + ++RQ F ++ QE+ +FD+ T EL +RL++D I + + + Sbjct: 138 AAGRQIKKIRQKFFHAILRQEMGWFDIKGTTELNTRLTDDVSKISEGIGDKVGMFFQAIA 197 Query: 209 TTAIGLGFMFSTSWKLTLLALVIVPVISVAVRKFGRFLRELSHQTQXXXXXXXXXXXXXF 388 T G F WKLTL+ + I P++ ++ + + L S + Sbjct: 198 TFFAGFIVGFIRGWKLTLVIMAISPILGLSTAVWAKILSTFSDKELAAYAKAGAVAEEAP 257 Query: 389 GAIRTVRAFAQEPHEISRYGGKVNETLKLGLKQA 490 GAIRTV AF + E+ RY + K+G+K+A Sbjct: 258 GAIRTVIAFGGQNKELERYQKHLENAKKIGIKKA 291 Score = 65.5 bits (158), Expect = 9e-11 Identities = 46/169 (27%), Positives = 79/169 (46%), Gaps = 2/169 (1%) Frame = +2 Query: 5 LRAWLFNSASERVVARLRQDLFSHLINQEIAFFDVTR--TGELLSRLSEDTQIIKNAATT 178 L+ + F A E + RLR F ++ Q++++FD + TG L +RL+ D ++ A T Sbjct: 768 LQGFTFGKAGEILTTRLRSMAFKAMLRQDMSWFDDHKNSTGALSTRLATDAAQVQGATGT 827 Query: 179 NLSEALRNLTTTAIGLGFMFSTSWKLTLLALVIVPVISVAVRKFGRFLRELSHQTQXXXX 358 L+ +N G+ F W+LTLL L +VP I+VA + L + + + Sbjct: 828 KLALIAQNTANLGTGIIISFIYGWQLTLLLLSVVPFIAVAGIVEMKMLAGNAKRDKKEME 887 Query: 359 XXXXXXXXXFGAIRTVRAFAQEPHEISRYGGKVNETLKLGLKQAKVVGL 505 IRTV + QE S Y K++ + +++A + G+ Sbjct: 888 AAGKIATEAIENIRTVVSLTQERKFESMYVEKLHGPYRNSVRKAHIYGI 936
>MDR22_ARATH (Q9LHK4) Putative multidrug resistance protein 22 (P-glycoprotein| 8) Length = 1241 Score = 75.9 bits (185), Expect = 7e-14 Identities = 45/179 (25%), Positives = 87/179 (48%), Gaps = 1/179 (0%) Frame = +2 Query: 5 LRAWLFNSASERVVARLRQDLFSHLINQEIAFFDVT-RTGELLSRLSEDTQIIKNAATTN 181 + + ++ SER V ++R+ ++ QE++FFD T E++ +S DT +I+ + Sbjct: 97 MEGYCWSKTSERQVMKIRRTYLEAVLRQEVSFFDSDISTSEIIHTISTDTSLIQQLLSEK 156 Query: 182 LSEALRNLTTTAIGLGFMFSTSWKLTLLALVIVPVISVAVRKFGRFLRELSHQTQXXXXX 361 + L +++ GL F SW+LT++A+ + ++ + +G++L LS ++ Sbjct: 157 VPIFLMHISVFITGLVFSAYFSWRLTVVAIPTLVLLLIPGLIYGKYLVHLSKKSFKEYTK 216 Query: 362 XXXXXXXXFGAIRTVRAFAQEPHEISRYGGKVNETLKLGLKQAKVVGLFSGGLNAASTL 538 +I+T+ +F E I +Y + KLGLKQ GL G + T+ Sbjct: 217 ANSIVEQALSSIKTILSFTAETQIIKKYSEVLERHKKLGLKQGLAKGLAVGSSGISFTI 275 Score = 48.9 bits (115), Expect = 9e-06 Identities = 27/96 (28%), Positives = 49/96 (51%), Gaps = 2/96 (2%) Frame = +2 Query: 5 LRAWLFNSASERVVARLRQDLFSHLINQEIAFFDVTR--TGELLSRLSEDTQIIKNAATT 178 L+ + F ER++ RLR + + E A+FDV T E+ SRL+ + I+K+ Sbjct: 736 LQHYSFAKMGERLMQRLRLKMLEKIFTFEPAWFDVEENFTSEICSRLNNEVSIVKSLVAD 795 Query: 179 NLSEALRNLTTTAIGLGFMFSTSWKLTLLALVIVPV 286 +S ++ ++ I + SWKL L+ + + P+ Sbjct: 796 RISLLVQTISGVTIAMIIGLLISWKLALVMIAVQPL 831
>LMRA_LACLC (P97046) Multidrug resistance ABC transporter ATP-binding and| permease protein (EC 3.6.3.44) Length = 590 Score = 75.9 bits (185), Expect = 7e-14 Identities = 44/170 (25%), Positives = 78/170 (45%) Frame = +2 Query: 2 ALRAWLFNSASERVVARLRQDLFSHLINQEIAFFDVTRTGELLSRLSEDTQIIKNAATTN 181 A+ A + E VV LR ++ +I+ + +FD +TGE+ SRL+ DT +KN + Sbjct: 90 AIAAIVLGIFGESVVKNLRTRVWDKMIHLPVKYFDEVKTGEMSSRLANDTTQVKNLIANS 149 Query: 182 LSEALRNLTTTAIGLGFMFSTSWKLTLLALVIVPVISVAVRKFGRFLRELSHQTQXXXXX 361 + +A ++ + FM W+LTL ++ VP++ + + F +++ Q Sbjct: 150 IPQAFTSILLLVGSIIFMLQMQWRLTLAMIIAVPIVMLIMFPIMTFGQKIGWTRQDSLAN 209 Query: 362 XXXXXXXXFGAIRTVRAFAQEPHEISRYGGKVNETLKLGLKQAKVVGLFS 511 IR V++ E + VN K+G+K+A GL S Sbjct: 210 FQGIASESLSEIRLVKSSNAEKQASKKAENDVNALYKIGVKEAVFDGLMS 259
>MDR49_DROME (Q00449) Multidrug resistance protein homolog 49 (EC 3.6.3.44)| (P-glycoprotein 49) Length = 1302 Score = 75.5 bits (184), Expect = 9e-14 Identities = 43/149 (28%), Positives = 74/149 (49%), Gaps = 2/149 (1%) Frame = +2 Query: 5 LRAWLFNSASERVVARLRQDLFSHLINQEIAFFDVTRT--GELLSRLSEDTQIIKNAATT 178 L+ ++F +A ++ RLR+ F +I Q+IA+FD R G L SRL+ D ++ A Sbjct: 795 LQTYMFTTAGVKMTTRLRKRAFGTIIGQDIAYFDDERNSVGALCSRLASDCSNVQGATGA 854 Query: 179 NLSEALRNLTTTAIGLGFMFSTSWKLTLLALVIVPVISVAVRKFGRFLRELSHQTQXXXX 358 + L+ + T +G+ F SW+ TLL LV +P++ ++V GRF+ + + + + Sbjct: 855 RVGTMLQAVATLVVGMVVGFVFSWQQTLLTLVTLPLVCLSVYLEGRFIMKSAQKAKASIE 914 Query: 359 XXXXXXXXXFGAIRTVRAFAQEPHEISRY 445 IRTV E + +Y Sbjct: 915 EASQVAVEAITNIRTVNGLCLERQVLDQY 943 Score = 65.9 bits (159), Expect = 7e-11 Identities = 48/176 (27%), Positives = 76/176 (43%) Frame = +2 Query: 17 LFNSASERVVARLRQDLFSHLINQEIAFFDVTRTGELLSRLSEDTQIIKNAATTNLSEAL 196 L N + + R+R+ ++ Q+IA++D + S+++ED +K + + Sbjct: 139 LANRIALNQIDRIRKLFLEAMLRQDIAWYDTSSGSNFASKMTEDLDKLKEGIGEKIVIVV 198 Query: 197 RNLTTTAIGLGFMFSTSWKLTLLALVIVPVISVAVRKFGRFLRELSHQTQXXXXXXXXXX 376 + T IG+ F WKLTL+ L VP I A R L+ + Sbjct: 199 FLIMTFVIGIVSAFVYGWKLTLVVLSCVPFIIAATSVVARLQGSLAEKELKSYSDAANVV 258 Query: 377 XXXFGAIRTVRAFAQEPHEISRYGGKVNETLKLGLKQAKVVGLFSGGLNAASTLSV 544 F IRTV AF+ + E R+G + G K+ GL+SG NA S L + Sbjct: 259 EEVFSGIRTVFAFSGQEKEKERFGKLLIPAENTGRKK----GLYSGMGNALSWLII 310
>MDR15_ARATH (Q9C7F8) Putative multidrug resistance protein 15 (P-glycoprotein| 13) Length = 1245 Score = 75.1 bits (183), Expect = 1e-13 Identities = 47/173 (27%), Positives = 78/173 (45%), Gaps = 5/173 (2%) Frame = +2 Query: 11 AWL----FNSASERVVARLRQDLFSHLINQEIAFFDV-TRTGELLSRLSEDTQIIKNAAT 175 AW+ + ER ARLR + ++ ++I FFD R L+ +S D ++++A Sbjct: 107 AWIGVSCWMQTGERQTARLRINYLKSILAKDITFFDTEARDSNLIFHISSDAILVQDAIG 166 Query: 176 TNLSEALRNLTTTAIGLGFMFSTSWKLTLLALVIVPVISVAVRKFGRFLRELSHQTQXXX 355 LR L+ G F + W+LTLL L +VP+I++A + + +S +++ Sbjct: 167 DKTDHVLRYLSQFIAGFVIGFLSVWQLTLLTLGVVPLIAIAGGGYAIVMSTISEKSETAY 226 Query: 356 XXXXXXXXXXFGAIRTVRAFAQEPHEISRYGGKVNETLKLGLKQAKVVGLFSG 514 +RTV AF E + Y + + LKLG + GL G Sbjct: 227 ADAGKVAEEVMSQVRTVYAFVGEEKAVKSYSNSLKKALKLGKRSGLAKGLGVG 279 Score = 65.5 bits (158), Expect = 9e-11 Identities = 43/175 (24%), Positives = 78/175 (44%), Gaps = 2/175 (1%) Frame = +2 Query: 5 LRAWLFNSASERVVARLRQDLFSHLINQEIAFFDV--TRTGELLSRLSEDTQIIKNAATT 178 L+ + + ER+ +R+R LFS +++ EI +FD+ TG L S L+ D ++++A Sbjct: 741 LQHYFYTLMGERLTSRVRLSLFSAILSNEIGWFDLDENNTGSLTSILAADATLVRSALAD 800 Query: 179 NLSEALRNLTTTAIGLGFMFSTSWKLTLLALVIVPVISVAVRKFGRFLRELSHQTQXXXX 358 LS ++NL+ T L F SW++ + P++ A FL+ Sbjct: 801 RLSTIVQNLSLTVTALALAFFYSWRVAAVVTACFPLLIAASLTEQLFLKGFGGDYTRAYS 860 Query: 359 XXXXXXXXXFGAIRTVRAFAQEPHEISRYGGKVNETLKLGLKQAKVVGLFSGGLN 523 IRTV A+ E ++ ++++ K + + G F GL+ Sbjct: 861 RATSVAREAIANIRTVAAYGAEKQISEQFTCELSKPTKNAFVRGHISG-FGYGLS 914
>MDR2_RAT (Q08201) Multidrug resistance protein 2 (EC 3.6.3.44)| (P-glycoprotein 2) (P-glycoprotein 3) Length = 1278 Score = 75.1 bits (183), Expect = 1e-13 Identities = 42/154 (27%), Positives = 72/154 (46%) Frame = +2 Query: 29 ASERVVARLRQDLFSHLINQEIAFFDVTRTGELLSRLSEDTQIIKNAATTNLSEALRNLT 208 A+ R + ++RQ F ++ QE+ +FD+ T EL +RL++D I + + + Sbjct: 138 AAGRQIRKIRQKFFHAILRQEMGWFDIKGTTELNTRLTDDISKISEGIGDKVGMFFQAIA 197 Query: 209 TTAIGLGFMFSTSWKLTLLALVIVPVISVAVRKFGRFLRELSHQTQXXXXXXXXXXXXXF 388 T G F WKLTL+ + I ++ ++ + + L S + Sbjct: 198 TFFAGFIVGFIRGWKLTLVIMAITAILGLSTAVWAKILSTFSDKELAAYAKAGAVAEEAL 257 Query: 389 GAIRTVRAFAQEPHEISRYGGKVNETLKLGLKQA 490 GAIRTV AF + E+ RY + K+G+K+A Sbjct: 258 GAIRTVIAFGGQNKELERYQKHLENAKKIGIKKA 291 Score = 65.5 bits (158), Expect = 9e-11 Identities = 46/169 (27%), Positives = 79/169 (46%), Gaps = 2/169 (1%) Frame = +2 Query: 5 LRAWLFNSASERVVARLRQDLFSHLINQEIAFFDVTR--TGELLSRLSEDTQIIKNAATT 178 L+ + F A E + RLR F ++ Q++++FD + TG L +RL+ D ++ A T Sbjct: 770 LQGFTFGKAGEILTTRLRSMAFKAMLRQDMSWFDDHKNSTGALSTRLATDAAQVQGATGT 829 Query: 179 NLSEALRNLTTTAIGLGFMFSTSWKLTLLALVIVPVISVAVRKFGRFLRELSHQTQXXXX 358 L+ +N G+ F W+LTLL L +VP I+VA + L + + + Sbjct: 830 RLALIAQNTANLGTGIIISFIYGWQLTLLLLSVVPFIAVAGIVEMKMLAGNAKRDKKEME 889 Query: 359 XXXXXXXXXFGAIRTVRAFAQEPHEISRYGGKVNETLKLGLKQAKVVGL 505 IRTV + QE S Y K++ + +++A + G+ Sbjct: 890 AAGKIATEAIENIRTVVSLTQERKFESMYVEKLHGPYRNSVRKAHIYGI 938
>MSBA_HAEIN (P44407) Lipid A export ATP-binding/permease protein msbA| Length = 587 Score = 74.7 bits (182), Expect = 2e-13 Identities = 45/158 (28%), Positives = 77/158 (48%) Frame = +2 Query: 11 AWLFNSASERVVARLRQDLFSHLINQEIAFFDVTRTGELLSRLSEDTQIIKNAATTNLSE 190 AW+ S +VV +R+ LF HL+ ++FFD TG LLSR++ D+Q+I ++++ +L Sbjct: 94 AWV----SGKVVMTMRRRLFKHLMFMPVSFFDQNSTGRLLSRITYDSQMIASSSSGSLIT 149 Query: 191 ALRNLTTTAIGLGFMFSTSWKLTLLALVIVPVISVAVRKFGRFLRELSHQTQXXXXXXXX 370 +R MF TSW+LT++ +I P+I+V +R + R LS Q Sbjct: 150 IVREGAYIISLFAVMFYTSWELTIVLFIIGPIIAVLIRLVSKIFRRLSKNLQDSMGELTS 209 Query: 371 XXXXXFGAIRTVRAFAQEPHEISRYGGKVNETLKLGLK 484 + V +F + E + N+ + +K Sbjct: 210 ATEQMLKGHKVVLSFGGQHVEEVHFNHVSNDMRRKSMK 247
>MSBA_YERPS (Q66CI3) Lipid A export ATP-binding/permease protein msbA| Length = 582 Score = 74.7 bits (182), Expect = 2e-13 Identities = 44/152 (28%), Positives = 78/152 (51%), Gaps = 1/152 (0%) Frame = +2 Query: 32 SERVVARLRQDLFSHLINQEIAFFDVTRTGELLSRLSEDTQIIKNAATTNLSEALRNLTT 211 S +VV +R+ LFSH++ ++FFD TG LLSR++ D++ + ++++ L +R Sbjct: 93 SGKVVMHIRRRLFSHMMGMPVSFFDQQSTGTLLSRITYDSEQVAASSSSALVTVVRE-GA 151 Query: 212 TAIGLG-FMFSTSWKLTLLALVIVPVISVAVRKFGRFLRELSHQTQXXXXXXXXXXXXXF 388 + IGL MF SW+L+L+ +VI P++S+++R + R +S Q Sbjct: 152 SIIGLFIMMFYYSWQLSLILIVIAPIVSISIRLVSKRFRNISKNMQNTMGEVTTSAEQML 211 Query: 389 GAIRTVRAFAQEPHEISRYGGKVNETLKLGLK 484 + V F + E R+ N + G+K Sbjct: 212 KGHKEVLIFGGQKVETERFDAVSNRMRQQGMK 243
>MSBA_YERPE (Q8ZGA9) Lipid A export ATP-binding/permease protein msbA| Length = 582 Score = 74.7 bits (182), Expect = 2e-13 Identities = 44/152 (28%), Positives = 78/152 (51%), Gaps = 1/152 (0%) Frame = +2 Query: 32 SERVVARLRQDLFSHLINQEIAFFDVTRTGELLSRLSEDTQIIKNAATTNLSEALRNLTT 211 S +VV +R+ LFSH++ ++FFD TG LLSR++ D++ + ++++ L +R Sbjct: 93 SGKVVMHIRRRLFSHMMGMPVSFFDQQSTGTLLSRITYDSEQVAASSSSALVTVVRE-GA 151 Query: 212 TAIGLG-FMFSTSWKLTLLALVIVPVISVAVRKFGRFLRELSHQTQXXXXXXXXXXXXXF 388 + IGL MF SW+L+L+ +VI P++S+++R + R +S Q Sbjct: 152 SIIGLFIMMFYYSWQLSLILIVIAPIVSISIRLVSKRFRNISKNMQNTMGEVTTSAEQML 211 Query: 389 GAIRTVRAFAQEPHEISRYGGKVNETLKLGLK 484 + V F + E R+ N + G+K Sbjct: 212 KGHKEVLIFGGQKVETERFDAVSNRMRQQGMK 243
>MSBA_PHOLL (Q7N6C6) Lipid A export ATP-binding/permease protein msbA| Length = 581 Score = 74.3 bits (181), Expect = 2e-13 Identities = 44/152 (28%), Positives = 79/152 (51%), Gaps = 1/152 (0%) Frame = +2 Query: 32 SERVVARLRQDLFSHLINQEIAFFDVTRTGELLSRLSEDTQIIKNAATTNLSEALRNLTT 211 S +VV ++R+ LFSH++ ++FFD TG LLSR++ D++ + +++++ L +R Sbjct: 92 SGKVVMQMRRRLFSHMMGMPVSFFDQQSTGTLLSRITYDSEQVASSSSSALITVVRE-GA 150 Query: 212 TAIGL-GFMFSTSWKLTLLALVIVPVISVAVRKFGRFLRELSHQTQXXXXXXXXXXXXXF 388 + IGL MF SW+L+L+ +VI P++S+ +R + R +S Q Sbjct: 151 SIIGLFVLMFYYSWQLSLILIVIAPIVSLVIRVVSKRFRSISKNMQNSMGQVTASAEQML 210 Query: 389 GAIRTVRAFAQEPHEISRYGGKVNETLKLGLK 484 + V F + E R+ N + G+K Sbjct: 211 KGHKEVLIFGGQNVETERFNKVSNHMRQQGMK 242
>MSBA_WIGBR (Q8D2U8) Lipid A export ATP-binding/permease protein msbA| Length = 581 Score = 73.9 bits (180), Expect = 3e-13 Identities = 40/148 (27%), Positives = 81/148 (54%), Gaps = 1/148 (0%) Frame = +2 Query: 5 LRAWLFNSASERVVARLRQDLFSHLINQEIAFFDVTRTGELLSRLSEDTQIIKNAATTNL 184 + ++ + S +VV +R++LF H++N ++FFD TG LLSR++ DT+ + +++++ L Sbjct: 83 ISSYFISWVSGKVVMNIRRNLFRHMMNMPVSFFDKRSTGALLSRITYDTEQVASSSSSVL 142 Query: 185 SEALRNLTTTAIGLGF-MFSTSWKLTLLALVIVPVISVAVRKFGRFLRELSHQTQXXXXX 361 +R + IGL F MF SWKL+ + ++I P++ ++ + + R+++ + Q Sbjct: 143 ITIVRE-GSLIIGLFFMMFFHSWKLSSVLIIITPIVFFSINQVSKRFRKINKKIQNNMGQ 201 Query: 362 XXXXXXXXFGAIRTVRAFAQEPHEISRY 445 + +R F + EI R+ Sbjct: 202 VNFIVEQMLKGHKEIRIFGGQKEEIDRF 229
>MSBA_PASMU (Q9CMG7) Lipid A export ATP-binding/permease protein msbA| Length = 582 Score = 73.9 bits (180), Expect = 3e-13 Identities = 43/162 (26%), Positives = 80/162 (49%) Frame = +2 Query: 5 LRAWLFNSASERVVARLRQDLFSHLINQEIAFFDVTRTGELLSRLSEDTQIIKNAATTNL 184 + ++ + S +VV +R+ +F HL+ + FFD +G LLSR++ D++++ N+++ L Sbjct: 83 ISSYCLSWVSGKVVMIMRRRIFKHLMFMPVPFFDQNSSGRLLSRITYDSELVANSSSGAL 142 Query: 185 SEALRNLTTTAIGLGFMFSTSWKLTLLALVIVPVISVAVRKFGRFLRELSHQTQXXXXXX 364 +R L M TSW+L+++ +I P+I+V +R + RELS Q Sbjct: 143 ITIVREGAYIISLLAVMLYTSWQLSIVLFLIGPIIAVLIRFVSKRFRELSKNMQNSMGEL 202 Query: 365 XXXXXXXFGAIRTVRAFAQEPHEISRYGGKVNETLKLGLKQA 490 + V +F + E R+ N+ + G+K A Sbjct: 203 TSTAEQMLKGHKVVLSFGGQIVEEERFNHVSNDMRRKGMKMA 244
>MSBA_ERWCT (Q6D437) Lipid A export ATP-binding/permease protein msbA| Length = 582 Score = 73.6 bits (179), Expect = 3e-13 Identities = 45/152 (29%), Positives = 77/152 (50%), Gaps = 1/152 (0%) Frame = +2 Query: 32 SERVVARLRQDLFSHLINQEIAFFDVTRTGELLSRLSEDTQIIKNAATTNLSEALRNLTT 211 S +VV +R+ LFSH++ +AFFD TG LLSR++ D++ + +++ L +R Sbjct: 93 SGKVVMNMRRRLFSHIMGMPVAFFDQQSTGTLLSRITYDSEQVAASSSGALITVVRE-GA 151 Query: 212 TAIGLG-FMFSTSWKLTLLALVIVPVISVAVRKFGRFLRELSHQTQXXXXXXXXXXXXXF 388 + IGL MF SW+L+++ +VI P++S+A+R + R +S Q Sbjct: 152 SIIGLFILMFYYSWQLSIILIVIAPIVSIAMRMVSKRFRSISKNMQDTMGHVTTSTEQML 211 Query: 389 GAIRTVRAFAQEPHEISRYGGKVNETLKLGLK 484 + V F + E R+ N + G+K Sbjct: 212 KGHKEVLMFGGQDVETKRFEQVSNRMRQQGMK 243
>MSBA_SALTY (P63359) Lipid A export ATP-binding/permease protein msbA| Length = 582 Score = 72.0 bits (175), Expect = 1e-12 Identities = 43/161 (26%), Positives = 81/161 (50%), Gaps = 1/161 (0%) Frame = +2 Query: 5 LRAWLFNSASERVVARLRQDLFSHLINQEIAFFDVTRTGELLSRLSEDTQIIKNAATTNL 184 + ++ + S +VV +R+ LF H++ +AFFD TG LLSR++ D++ + ++++ L Sbjct: 84 ISSYCISWVSGKVVMTMRRRLFGHMMGMPVAFFDKQSTGTLLSRITYDSEQVASSSSGAL 143 Query: 185 SEALRNLTTTAIGLG-FMFSTSWKLTLLALVIVPVISVAVRKFGRFLRELSHQTQXXXXX 361 +R + IGL MF SW+L+++ +V+ P++S+A+R + R +S Q Sbjct: 144 ITVVRE-GASIIGLFIMMFYYSWQLSIILVVLAPIVSIAIRVVSKRFRSISKNMQNTMGQ 202 Query: 362 XXXXXXXXFGAIRTVRAFAQEPHEISRYGGKVNETLKLGLK 484 + V F + E R+ N+ G+K Sbjct: 203 VTTSAEQMLKGHKEVLIFGGQEVETKRFDKVSNKMRLQGMK 243
>MSBA_SALTI (P63360) Lipid A export ATP-binding/permease protein msbA| Length = 582 Score = 72.0 bits (175), Expect = 1e-12 Identities = 43/161 (26%), Positives = 81/161 (50%), Gaps = 1/161 (0%) Frame = +2 Query: 5 LRAWLFNSASERVVARLRQDLFSHLINQEIAFFDVTRTGELLSRLSEDTQIIKNAATTNL 184 + ++ + S +VV +R+ LF H++ +AFFD TG LLSR++ D++ + ++++ L Sbjct: 84 ISSYCISWVSGKVVMTMRRRLFGHMMGMPVAFFDKQSTGTLLSRITYDSEQVASSSSGAL 143 Query: 185 SEALRNLTTTAIGLG-FMFSTSWKLTLLALVIVPVISVAVRKFGRFLRELSHQTQXXXXX 361 +R + IGL MF SW+L+++ +V+ P++S+A+R + R +S Q Sbjct: 144 ITVVRE-GASIIGLFIMMFYYSWQLSIILVVLAPIVSIAIRVVSKRFRSISKNMQNTMGQ 202 Query: 362 XXXXXXXXFGAIRTVRAFAQEPHEISRYGGKVNETLKLGLK 484 + V F + E R+ N+ G+K Sbjct: 203 VTTSAEQMLKGHKEVLIFGGQEVETKRFDKVSNKMRLQGMK 243
>MSBA_LEGPL (Q5WVN2) Lipid A export ATP-binding/permease protein msbA| Length = 588 Score = 72.0 bits (175), Expect = 1e-12 Identities = 40/163 (24%), Positives = 78/163 (47%) Frame = +2 Query: 2 ALRAWLFNSASERVVARLRQDLFSHLINQEIAFFDVTRTGELLSRLSEDTQIIKNAATTN 181 +L ++ + VV LRQ +FSH+I+ ++D +G+LLS++ D + + + Sbjct: 83 SLGSYCMTWVARSVVKVLRQTVFSHIIHLPADYYDEATSGQLLSKILYDVEQVAQVSADA 142 Query: 182 LSEALRNLTTTAIGLGFMFSTSWKLTLLALVIVPVISVAVRKFGRFLRELSHQTQXXXXX 361 L++ ++N+ L M W+L+L+ L+ +P + + V + +R +SH+ Q Sbjct: 143 LTDFIQNICLVIGLLTVMMVICWQLSLMFLLTIPFVGIIVNYTNKRVRRISHKVQKTMGE 202 Query: 362 XXXXXXXXFGAIRTVRAFAQEPHEISRYGGKVNETLKLGLKQA 490 R VR F E +EI+++ + K +K A Sbjct: 203 VTEIASEAIEGYRVVRIFGGERYEITKFNKATEYSRKNDMKVA 245
>MSBA_LEGPH (Q5ZUH9) Lipid A export ATP-binding/permease protein msbA| Length = 588 Score = 72.0 bits (175), Expect = 1e-12 Identities = 40/163 (24%), Positives = 78/163 (47%) Frame = +2 Query: 2 ALRAWLFNSASERVVARLRQDLFSHLINQEIAFFDVTRTGELLSRLSEDTQIIKNAATTN 181 +L ++ + VV LRQ +FSH+I+ ++D +G+LLS++ D + + + Sbjct: 83 SLGSYCMTWVARSVVKVLRQTVFSHIIHLPADYYDEATSGQLLSKILYDVEQVAQVSADA 142 Query: 182 LSEALRNLTTTAIGLGFMFSTSWKLTLLALVIVPVISVAVRKFGRFLRELSHQTQXXXXX 361 L++ ++N+ L M W+L+L+ L+ +P + + V + +R +SH+ Q Sbjct: 143 LTDFIQNICLVIGLLTVMMVICWQLSLMFLLTIPFVGIIVNYTNKRVRRISHKVQKTMGE 202 Query: 362 XXXXXXXXFGAIRTVRAFAQEPHEISRYGGKVNETLKLGLKQA 490 R VR F E +EI+++ + K +K A Sbjct: 203 VTEIASEAIEGYRVVRIFGGERYEITKFNKATEYSRKNDMKVA 245
>MSBA_LEGPA (Q5X498) Lipid A export ATP-binding/permease protein msbA| Length = 588 Score = 72.0 bits (175), Expect = 1e-12 Identities = 40/163 (24%), Positives = 78/163 (47%) Frame = +2 Query: 2 ALRAWLFNSASERVVARLRQDLFSHLINQEIAFFDVTRTGELLSRLSEDTQIIKNAATTN 181 +L ++ + VV LRQ +FSH+I+ ++D +G+LLS++ D + + + Sbjct: 83 SLGSYCMTWVARSVVKVLRQTVFSHIIHLPADYYDEATSGQLLSKILYDVEQVAQVSADA 142 Query: 182 LSEALRNLTTTAIGLGFMFSTSWKLTLLALVIVPVISVAVRKFGRFLRELSHQTQXXXXX 361 L++ ++N+ L M W+L+L+ L+ +P + + V + +R +SH+ Q Sbjct: 143 LTDFIQNICLVIGLLTVMMVICWQLSLMFLLTIPFVGIIVNYTNKRVRRISHKVQKTMGE 202 Query: 362 XXXXXXXXFGAIRTVRAFAQEPHEISRYGGKVNETLKLGLKQA 490 R VR F E +EI+++ + K +K A Sbjct: 203 VTEIASEAIEGYRVVRIFGGERYEITKFNKATEYSRKNDMKVA 245
>MDLA_BUCAP (Q8K985) Multidrug resistance-like ATP-binding protein mdlA (EC| 3.6.3.44) Length = 581 Score = 72.0 bits (175), Expect = 1e-12 Identities = 42/168 (25%), Positives = 84/168 (50%), Gaps = 4/168 (2%) Frame = +2 Query: 17 LFNSASERVVARLRQDLFSHLINQEIAFFDVTRTGELLSRLSEDTQIIKNAATTNLSEAL 196 L AS ++ LR +S+L Q FF RTG+L++R + D + AA + L Sbjct: 80 LLFGASYQLATELRVKFYSYLSKQSEIFFLKNRTGDLIARATNDVDRVVFAAGEGV---L 136 Query: 197 RNLTTTAIGLGFMF----STSWKLTLLALVIVPVISVAVRKFGRFLRELSHQTQXXXXXX 364 + ++ +G+ + SW LT+++L+ +P++++ ++K+G+ L + Q Sbjct: 137 TLVDSSVMGISVLIVMITQISWLLTIISLIPMPIMAILIKKYGKKLHDTFRNAQSAFSLL 196 Query: 365 XXXXXXXFGAIRTVRAFAQEPHEISRYGGKVNETLKLGLKQAKVVGLF 508 +IR +RAF E +++ ++ VN+T K ++ A++ F Sbjct: 197 NNQTQEILTSIRMIRAFGLEKNQLKKFNNIVNDTGKKNMEVAEIDARF 244
>MDR1_LEIEN (Q06034) Multidrug resistance protein 1 (EC 3.6.3.44)| (P-glycoprotein 1) Length = 1280 Score = 72.0 bits (175), Expect = 1e-12 Identities = 41/139 (29%), Positives = 72/139 (51%) Frame = +2 Query: 29 ASERVVARLRQDLFSHLINQEIAFFDVTRTGELLSRLSEDTQIIKNAATTNLSEALRNLT 208 A+ R VAR+R F ++ Q+I + D G L +R++ DT++I+N LS+ + N + Sbjct: 139 AACRQVARIRLLFFRAVLRQDIGWHDEHSPGALTARMTGDTRVIQNGINDKLSQGIMNGS 198 Query: 209 TTAIGLGFMFSTSWKLTLLALVIVPVISVAVRKFGRFLRELSHQTQXXXXXXXXXXXXXF 388 IG F SW+LTL+ + ++P I V G + +++ ++ Sbjct: 199 MGVIGYIAGFVFSWELTLMMIGMMPFIIVMAAIIGSIVSKITESSRKYFAKAGSLATEVM 258 Query: 389 GAIRTVRAFAQEPHEISRY 445 IRTV+AF +E +E+ R+ Sbjct: 259 ENIRTVQAFGREDYELERF 277
>MDR19_ARATH (Q9LSJ6) Putative multidrug resistance protein 19 (P-glycoprotein| 17) Length = 1240 Score = 71.6 bits (174), Expect = 1e-12 Identities = 41/172 (23%), Positives = 79/172 (45%), Gaps = 2/172 (1%) Frame = +2 Query: 5 LRAWLFNSASERVVARLRQDLFSHLINQEIAFFD--VTRTGELLSRLSEDTQIIKNAATT 178 L + + ER AR+R+ ++ Q++ +FD VT T ++++ +S D+ +I++ + Sbjct: 97 LEGYCWTRTGERQAARMREKYLRAVLRQDVGYFDLHVTSTSDVITSISSDSLVIQDFLSE 156 Query: 179 NLSEALRNLTTTAIGLGFMFSTSWKLTLLALVIVPVISVAVRKFGRFLRELSHQTQXXXX 358 L L N + F W+LT++ + ++ V +GR L +S + Sbjct: 157 KLPNFLMNASAFVASYIVSFILMWRLTIVGFPFIILLLVPGLMYGRALVSISRKIHEQYN 216 Query: 359 XXXXXXXXXFGAIRTVRAFAQEPHEISRYGGKVNETLKLGLKQAKVVGLFSG 514 ++RTV AF E I ++ + ++KLGL+Q G+ G Sbjct: 217 EAGSIAEQAISSVRTVYAFGSENKMIGKFSTALRGSVKLGLRQGLAKGITIG 268 Score = 51.2 bits (121), Expect = 2e-06 Identities = 28/137 (20%), Positives = 62/137 (45%), Gaps = 2/137 (1%) Frame = +2 Query: 20 FNSASERVVARLRQDLFSHLINQEIAFFDV--TRTGELLSRLSEDTQIIKNAATTNLSEA 193 F E + R+R+ + S ++ E+ +FD+ +G + SRL++D ++++ +S Sbjct: 737 FAYMGEYLTKRIREQMLSKILTFEVNWFDIDDNSSGAICSRLAKDANVVRSMVGDRMSLL 796 Query: 194 LRNLTTTAIGLGFMFSTSWKLTLLALVIVPVISVAVRKFGRFLRELSHQTQXXXXXXXXX 373 ++ ++ I +W+L ++ + + P+I V L+ LS + Sbjct: 797 VQTISAVIIACIIGLVIAWRLAIVMISVQPLIVVCFYTQRVLLKSLSEKASKAQDESSKL 856 Query: 374 XXXXFGAIRTVRAFAQE 424 IRT+ AF+ + Sbjct: 857 AAEAVSNIRTITAFSSQ 873
>MDR13_ARATH (Q9LHD1) Multidrug resistance protein 13 (P-glycoprotein 15)| Length = 1240 Score = 71.2 bits (173), Expect = 2e-12 Identities = 44/179 (24%), Positives = 88/179 (49%), Gaps = 4/179 (2%) Frame = +2 Query: 5 LRAWLFNSASERVVARLRQDLFSHLINQEIAFFD--VTRTGELLSRLSEDTQIIKNAATT 178 L + + ER AR+R+ ++ Q++ +FD VT T ++++ +S D+ +I++ + Sbjct: 97 LEGYCWTRTGERQTARMREKYLRAVLRQDVGYFDLHVTSTSDVITSVSSDSFVIQDVLSE 156 Query: 179 NLSEALRNLTTTAIGLGFMFSTSWKLTLLALVIVPVISVAVRKFGRFLRELSHQTQXXXX 358 L L + +T F W+L ++ L + ++ + +GR L +S + + Sbjct: 157 KLPNFLMSASTFVGSYIVGFILLWRLAIVGLPFIVLLVIPGLMYGRALISISRKIREEYN 216 Query: 359 XXXXXXXXXFGAIRTVRAFAQEPHEISRYGGKVNETLKLGLKQ--AKVVGLFSGGLNAA 529 ++RTV AF+ E IS++ + ++KLG+KQ AK + + S G+ A Sbjct: 217 EAGFVAEQAISSVRTVYAFSGERKTISKFSTALQGSVKLGIKQGLAKGITIGSNGITFA 275 Score = 49.3 bits (116), Expect = 7e-06 Identities = 27/137 (19%), Positives = 61/137 (44%), Gaps = 2/137 (1%) Frame = +2 Query: 20 FNSASERVVARLRQDLFSHLINQEIAFFD--VTRTGELLSRLSEDTQIIKNAATTNLSEA 193 F E + R+R+ + S ++ E+ +FD +G + SRL++D ++++ ++ Sbjct: 737 FAYMGEYLTKRIRERMLSKVLTFEVGWFDRDENSSGAICSRLAKDANVVRSLVGDRMALV 796 Query: 194 LRNLTTTAIGLGFMFSTSWKLTLLALVIVPVISVAVRKFGRFLRELSHQTQXXXXXXXXX 373 ++ ++ I +W+L L+ + + PVI V L+ +S + Sbjct: 797 VQTVSAVTIAFTMGLVIAWRLALVMIAVQPVIIVCFYTRRVLLKSMSKKAIKAQDESSKL 856 Query: 374 XXXXFGAIRTVRAFAQE 424 +RT+ AF+ + Sbjct: 857 AAEAVSNVRTITAFSSQ 873
>MSBA_ECOL6 (Q8FJB1) Lipid A export ATP-binding/permease protein msbA| Length = 582 Score = 70.9 bits (172), Expect = 2e-12 Identities = 42/161 (26%), Positives = 80/161 (49%), Gaps = 1/161 (0%) Frame = +2 Query: 5 LRAWLFNSASERVVARLRQDLFSHLINQEIAFFDVTRTGELLSRLSEDTQIIKNAATTNL 184 + ++ + S +VV +R+ LF H++ ++FFD TG LLSR++ D++ + ++++ L Sbjct: 84 ISSYCISWVSGKVVMTMRRRLFGHMMGMPVSFFDKQSTGTLLSRITYDSEQVASSSSGAL 143 Query: 185 SEALRNLTTTAIGLG-FMFSTSWKLTLLALVIVPVISVAVRKFGRFLRELSHQTQXXXXX 361 +R + IGL MF SW+L+++ +V+ P++S+A+R + R +S Q Sbjct: 144 ITVVRE-GASIIGLFIMMFYYSWQLSIILIVLAPIVSIAIRVVSKRFRNISKNMQNTMGQ 202 Query: 362 XXXXXXXXFGAIRTVRAFAQEPHEISRYGGKVNETLKLGLK 484 + V F + E R+ N G+K Sbjct: 203 VTTSAEQMLKGHKEVLIFGGQEVETKRFDKVSNRMRLQGMK 243
>MSBA_PSESM (Q87VF3) Lipid A export ATP-binding/permease protein msbA| Length = 600 Score = 70.9 bits (172), Expect = 2e-12 Identities = 41/157 (26%), Positives = 75/157 (47%) Frame = +2 Query: 41 VVARLRQDLFSHLINQEIAFFDVTRTGELLSRLSEDTQIIKNAATTNLSEALRNLTTTAI 220 +V LR +LF+ L+ +FD T +G L+SR++ + ++ AAT + +R T Sbjct: 109 LVHDLRVELFNKLLVLPNRYFDTTNSGHLISRITFNVTMVTGAATDAIKVVIREGLTVVF 168 Query: 221 GLGFMFSTSWKLTLLALVIVPVISVAVRKFGRFLRELSHQTQXXXXXXXXXXXXXFGAIR 400 ++ +WKLTL+ L I+P+I+V V + R+ S + Q R Sbjct: 169 LFIYLLMMNWKLTLVMLAILPLIAVMVSSASKKFRKQSKKIQVAMGDVTHVASETIQGYR 228 Query: 401 TVRAFAQEPHEISRYGGKVNETLKLGLKQAKVVGLFS 511 VR+F E +E +R+ + + L+ K +++ Sbjct: 229 VVRSFGGEAYEQNRFAEASDSNTRKQLRMTKTGAIYT 265
>MSBA_SHIFL (Q83LP0) Lipid A export ATP-binding/permease protein msbA| Length = 582 Score = 70.5 bits (171), Expect = 3e-12 Identities = 42/152 (27%), Positives = 76/152 (50%), Gaps = 1/152 (0%) Frame = +2 Query: 32 SERVVARLRQDLFSHLINQEIAFFDVTRTGELLSRLSEDTQIIKNAATTNLSEALRNLTT 211 S +VV +R+ LF H++ ++FFD TG LLSR++ D++ + ++++ L +R Sbjct: 93 SGKVVMTMRRRLFGHMMGMPVSFFDKQSTGTLLSRITYDSEQVASSSSGALITVVRE-GA 151 Query: 212 TAIGLG-FMFSTSWKLTLLALVIVPVISVAVRKFGRFLRELSHQTQXXXXXXXXXXXXXF 388 + IGL MF SW+L+++ +V+ P++S+A+R + R +S Q Sbjct: 152 SIIGLFIMMFYYSWQLSIILIVLAPIVSIAIRVVSKRFRNISKNMQNTMGQVTTSAEQML 211 Query: 389 GAIRTVRAFAQEPHEISRYGGKVNETLKLGLK 484 + V F + E R+ N G+K Sbjct: 212 KGHKEVLIFGGQEVETKRFDKVSNRMRLQGMK 243
>MSBA_ECOLI (P60752) Lipid A export ATP-binding/permease protein msbA| Length = 582 Score = 70.5 bits (171), Expect = 3e-12 Identities = 42/152 (27%), Positives = 76/152 (50%), Gaps = 1/152 (0%) Frame = +2 Query: 32 SERVVARLRQDLFSHLINQEIAFFDVTRTGELLSRLSEDTQIIKNAATTNLSEALRNLTT 211 S +VV +R+ LF H++ ++FFD TG LLSR++ D++ + ++++ L +R Sbjct: 93 SGKVVMTMRRRLFGHMMGMPVSFFDKQSTGTLLSRITYDSEQVASSSSGALITVVRE-GA 151 Query: 212 TAIGLG-FMFSTSWKLTLLALVIVPVISVAVRKFGRFLRELSHQTQXXXXXXXXXXXXXF 388 + IGL MF SW+L+++ +V+ P++S+A+R + R +S Q Sbjct: 152 SIIGLFIMMFYYSWQLSIILIVLAPIVSIAIRVVSKRFRNISKNMQNTMGQVTTSAEQML 211 Query: 389 GAIRTVRAFAQEPHEISRYGGKVNETLKLGLK 484 + V F + E R+ N G+K Sbjct: 212 KGHKEVLIFGGQEVETKRFDKVSNRMRLQGMK 243
>MSBA_ECO57 (P60753) Lipid A export ATP-binding/permease protein msbA| Length = 582 Score = 70.5 bits (171), Expect = 3e-12 Identities = 42/152 (27%), Positives = 76/152 (50%), Gaps = 1/152 (0%) Frame = +2 Query: 32 SERVVARLRQDLFSHLINQEIAFFDVTRTGELLSRLSEDTQIIKNAATTNLSEALRNLTT 211 S +VV +R+ LF H++ ++FFD TG LLSR++ D++ + ++++ L +R Sbjct: 93 SGKVVMTMRRRLFGHMMGMPVSFFDKQSTGTLLSRITYDSEQVASSSSGALITVVRE-GA 151 Query: 212 TAIGLG-FMFSTSWKLTLLALVIVPVISVAVRKFGRFLRELSHQTQXXXXXXXXXXXXXF 388 + IGL MF SW+L+++ +V+ P++S+A+R + R +S Q Sbjct: 152 SIIGLFIMMFYYSWQLSIILIVLAPIVSIAIRVVSKRFRNISKNMQNTMGQVTTSAEQML 211 Query: 389 GAIRTVRAFAQEPHEISRYGGKVNETLKLGLK 484 + V F + E R+ N G+K Sbjct: 212 KGHKEVLIFGGQEVETKRFDKVSNRMRLQGMK 243
>MDR12_ARATH (Q9C7F2) Multidrug resistance protein 12 (P-glycoprotein 14)| Length = 1247 Score = 70.5 bits (171), Expect = 3e-12 Identities = 45/173 (26%), Positives = 75/173 (43%), Gaps = 5/173 (2%) Frame = +2 Query: 11 AWL----FNSASERVVARLRQDLFSHLINQEIAFFDV-TRTGELLSRLSEDTQIIKNAAT 175 AW+ + ER ARLR + ++ ++I FFD R + +S D ++++A Sbjct: 108 AWIGVACWMQTGERQTARLRINYLKSILAKDITFFDTEARDSNFIFHISSDAILVQDAIG 167 Query: 176 TNLSEALRNLTTTAIGLGFMFSTSWKLTLLALVIVPVISVAVRKFGRFLRELSHQTQXXX 355 LR L G F + W+LTLL L +VP+I++A + + +S +++ Sbjct: 168 DKTGHVLRYLCQFIAGFVIGFLSVWQLTLLTLGVVPLIAIAGGGYAIVMSTISEKSEAAY 227 Query: 356 XXXXXXXXXXFGAIRTVRAFAQEPHEISRYGGKVNETLKLGLKQAKVVGLFSG 514 +RTV AF E + Y + + LKL + GL G Sbjct: 228 ADAGKVAEEVMSQVRTVYAFVGEEKAVKSYSNSLKKALKLSKRSGLAKGLGVG 280 Score = 68.6 bits (166), Expect = 1e-11 Identities = 45/175 (25%), Positives = 80/175 (45%), Gaps = 2/175 (1%) Frame = +2 Query: 5 LRAWLFNSASERVVARLRQDLFSHLINQEIAFFDV--TRTGELLSRLSEDTQIIKNAATT 178 L+ + + ER+ +R+R LFS +++ EI +FD+ TG L S L+ D ++++A Sbjct: 743 LQHYFYTLMGERLTSRVRLSLFSAILSNEIGWFDLDENNTGSLTSILAADATLVRSAIAD 802 Query: 179 NLSEALRNLTTTAIGLGFMFSTSWKLTLLALVIVPVISVAVRKFGRFLRELSHQTQXXXX 358 LS ++NL+ T L F SW++ + P++ A FL+ Sbjct: 803 RLSTIVQNLSLTITALALAFFYSWRVAAVVTACFPLLIAASLTEQLFLKGFGGDYTRAYS 862 Query: 359 XXXXXXXXXFGAIRTVRAFAQEPHEISRYGGKVNETLKLGLKQAKVVGLFSGGLN 523 IRTV AF+ E ++ ++++ K L + + G F GL+ Sbjct: 863 RATSLAREAISNIRTVAAFSAEKQISEQFTCELSKPTKSALLRGHISG-FGYGLS 916
>MDR2_ARATH (Q8LPK2) Multidrug resistance protein 2 (P-glycoprotein 2)| Length = 1233 Score = 70.5 bits (171), Expect = 3e-12 Identities = 43/170 (25%), Positives = 81/170 (47%), Gaps = 1/170 (0%) Frame = +2 Query: 35 ERVVARLRQDLFSHLINQEIAFFDV-TRTGELLSRLSEDTQIIKNAATTNLSEALRNLTT 211 ER A++R+ +++Q+I+ FD TGE++S ++ D ++++A + + L ++ Sbjct: 109 ERQAAKMRRAYLRSMLSQDISLFDTEASTGEVISAITSDILVVQDALSEKVGNFLHYISR 168 Query: 212 TAIGLGFMFSTSWKLTLLALVIVPVISVAVRKFGRFLRELSHQTQXXXXXXXXXXXXXFG 391 G F++ W+++L+ L IVP+I++A + L + + G Sbjct: 169 FIAGFAIGFTSVWQISLVTLSIVPLIALAGGIYAFVAIGLIARVRKSYIKAGEIAEEVIG 228 Query: 392 AIRTVRAFAQEPHEISRYGGKVNETLKLGLKQAKVVGLFSGGLNAASTLS 541 +RTV+AF E + Y + T K G K GL G ++ LS Sbjct: 229 NVRTVQAFTGEERAVRLYREALENTYKYGRKAGLTKGLGLGSMHCVLFLS 278 Score = 65.1 bits (157), Expect = 1e-10 Identities = 43/167 (25%), Positives = 71/167 (42%), Gaps = 2/167 (1%) Frame = +2 Query: 20 FNSASERVVARLRQDLFSHLINQEIAFFD-VTRTGELL-SRLSEDTQIIKNAATTNLSEA 193 F + ER+ R+R+++F ++ EI +FD V T +L SRL D ++K + Sbjct: 734 FGTMGERLTLRVRENMFRAILKNEIGWFDEVDNTSSMLASRLESDATLLKTIVVDRSTIL 793 Query: 194 LRNLTTTAIGLGFMFSTSWKLTLLALVIVPVISVAVRKFGRFLRELSHQTQXXXXXXXXX 373 L+NL F +W+LTL+ L P++ F++ Sbjct: 794 LQNLGLVVTSFIIAFILNWRLTLVVLATYPLVISGHISEKLFMQGYGGDLNKAYLKANML 853 Query: 374 XXXXFGAIRTVRAFAQEPHEISRYGGKVNETLKLGLKQAKVVGLFSG 514 IRTV AF E + Y ++ E K ++ ++ GLF G Sbjct: 854 AGESVSNIRTVAAFCAEEKILELYSRELLEPSKSSFRRGQIAGLFYG 900
>MDLB_ECOLI (P0AAG5) Multidrug resistance-like ATP-binding protein mdlB (EC| 3.6.3.44) Length = 593 Score = 70.5 bits (171), Expect = 3e-12 Identities = 38/149 (25%), Positives = 76/149 (51%) Frame = +2 Query: 17 LFNSASERVVARLRQDLFSHLINQEIAFFDVTRTGELLSRLSEDTQIIKNAATTNLSEAL 196 LFN A+ VV +LR D+ + Q ++ FD G+++SR++ DT++I++ T ++ L Sbjct: 88 LFNRAAVGVVQQLRTDVMDAALRQPLSEFDTQPVGQVISRVTNDTEVIRDLYVTVVATVL 147 Query: 197 RNLTTTAIGLGFMFSTSWKLTLLALVIVPVISVAVRKFGRFLRELSHQTQXXXXXXXXXX 376 R+ L MFS W++ L+A++I PV+ V + + R+ + + + Sbjct: 148 RSAALVGAMLVAMFSLDWRMALVAIMIFPVVLVVMVIYQRYSTPIVRRVRAYLADINDGF 207 Query: 377 XXXFGAIRTVRAFAQEPHEISRYGGKVNE 463 + ++ F Q+ +R+G ++ E Sbjct: 208 NEIINGMSVIQQFRQQ----ARFGERMGE 232
>MDLB_ECOL6 (P0AAG6) Multidrug resistance-like ATP-binding protein mdlB (EC| 3.6.3.44) Length = 593 Score = 70.5 bits (171), Expect = 3e-12 Identities = 38/149 (25%), Positives = 76/149 (51%) Frame = +2 Query: 17 LFNSASERVVARLRQDLFSHLINQEIAFFDVTRTGELLSRLSEDTQIIKNAATTNLSEAL 196 LFN A+ VV +LR D+ + Q ++ FD G+++SR++ DT++I++ T ++ L Sbjct: 88 LFNRAAVGVVQQLRTDVMDAALRQPLSEFDTQPVGQVISRVTNDTEVIRDLYVTVVATVL 147 Query: 197 RNLTTTAIGLGFMFSTSWKLTLLALVIVPVISVAVRKFGRFLRELSHQTQXXXXXXXXXX 376 R+ L MFS W++ L+A++I PV+ V + + R+ + + + Sbjct: 148 RSAALVGAMLVAMFSLDWRMALVAIMIFPVVLVVMVIYQRYSTPIVRRVRAYLADINDGF 207 Query: 377 XXXFGAIRTVRAFAQEPHEISRYGGKVNE 463 + ++ F Q+ +R+G ++ E Sbjct: 208 NEIINGMSVIQQFRQQ----ARFGERMGE 232
>MDLB_ECO57 (P0AAG7) Multidrug resistance-like ATP-binding protein mdlB (EC| 3.6.3.44) Length = 593 Score = 70.5 bits (171), Expect = 3e-12 Identities = 38/149 (25%), Positives = 76/149 (51%) Frame = +2 Query: 17 LFNSASERVVARLRQDLFSHLINQEIAFFDVTRTGELLSRLSEDTQIIKNAATTNLSEAL 196 LFN A+ VV +LR D+ + Q ++ FD G+++SR++ DT++I++ T ++ L Sbjct: 88 LFNRAAVGVVQQLRTDVMDAALRQPLSEFDTQPVGQVISRVTNDTEVIRDLYVTVVATVL 147 Query: 197 RNLTTTAIGLGFMFSTSWKLTLLALVIVPVISVAVRKFGRFLRELSHQTQXXXXXXXXXX 376 R+ L MFS W++ L+A++I PV+ V + + R+ + + + Sbjct: 148 RSAALVGAMLVAMFSLDWRMALVAIMIFPVVLVVMVIYQRYSTPIVRRVRAYLADINDGF 207 Query: 377 XXXFGAIRTVRAFAQEPHEISRYGGKVNE 463 + ++ F Q+ +R+G ++ E Sbjct: 208 NEIINGMSVIQQFRQQ----ARFGERMGE 232
>MSBA_ACIAD (Q6F9X0) Lipid A export ATP-binding/permease protein msbA| Length = 574 Score = 70.5 bits (171), Expect = 3e-12 Identities = 42/160 (26%), Positives = 79/160 (49%) Frame = +2 Query: 32 SERVVARLRQDLFSHLINQEIAFFDVTRTGELLSRLSEDTQIIKNAATTNLSEALRNLTT 211 S R++ +RQ++++ LI ++ +G + +++ + + + A++ +L +++ Sbjct: 87 SRRLIFSIRQEIYAKLIRLPSQYYLDNSSGHISAKIMYNVEQLTAASSESLKIMVKDGLI 146 Query: 212 TAIGLGFMFSTSWKLTLLALVIVPVISVAVRKFGRFLRELSHQTQXXXXXXXXXXXXXFG 391 T LG++ T+W+LTL + +P+I V VRK + +R+LS Q Q G Sbjct: 147 TLGLLGYLLYTNWRLTLCIFIFMPIIGVLVRKASKRMRKLSIQVQNTMGDVNHVVQESIG 206 Query: 392 AIRTVRAFAQEPHEISRYGGKVNETLKLGLKQAKVVGLFS 511 V++F E E R+ + LK GLK V L S Sbjct: 207 GQAVVKSFVGEEFEQKRFYKSSEDNLKRGLKMVIVQNLNS 246
>MDR7_ARATH (Q9FHF1) Multidrug resistance protein 7 (P-glycoprotein 7)| Length = 1248 Score = 70.1 bits (170), Expect = 4e-12 Identities = 46/173 (26%), Positives = 82/173 (47%), Gaps = 2/173 (1%) Frame = +2 Query: 5 LRAWLFNSASERVVARLRQDLFSHLINQEIAFFDVTR--TGELLSRLSEDTQIIKNAATT 178 L+ +LF A +++ R+R F +++Q+I++FD T+ +G + +RLS D +K+ Sbjct: 742 LQNYLFAIAGAKLIKRIRSLSFDRVLHQDISWFDDTKNSSGVIGARLSTDASTVKSIVGD 801 Query: 179 NLSEALRNLTTTAIGLGFMFSTSWKLTLLALVIVPVISVAVRKFGRFLRELSHQTQXXXX 358 L ++N+ T F+ +W L L+AL++ PV+ +F+ + + Sbjct: 802 VLGLIMQNMATIIGAFIIAFTANWLLALMALLVAPVMFFQGYYQIKFITGFGAKARGKYE 861 Query: 359 XXXXXXXXXFGAIRTVRAFAQEPHEISRYGGKVNETLKLGLKQAKVVGLFSGG 517 +IRTV +F E + Y K +E + G K V GL GG Sbjct: 862 EASQVASDAVSSIRTVASFCAEDKVMDLYQEKCDEPKQQGFKLGLVSGLCYGG 914 Score = 63.9 bits (154), Expect = 3e-10 Identities = 46/161 (28%), Positives = 75/161 (46%), Gaps = 1/161 (0%) Frame = +2 Query: 35 ERVVARLRQDLFSHLINQEIAFFDV-TRTGELLSRLSEDTQIIKNAATTNLSEALRNLTT 211 ER R+R+ ++ Q+I FFD T TGE++ R+S DT +I+++ + + + +++ Sbjct: 105 ERQSTRIRRLYLKTILRQDIGFFDTETNTGEVIGRMSGDTILIQDSMGEKVGKFTQLVSS 164 Query: 212 TAIGLGFMFSTSWKLTLLALVIVPVISVAVRKFGRFLRELSHQTQXXXXXXXXXXXXXFG 391 G F KLTL L VP+I + + + + Q G Sbjct: 165 FVGGFTVAFIVGMKLTLALLPCVPLIVGTGGAMTYIMSKKAQRVQLAYTEAGNVVQQAVG 224 Query: 392 AIRTVRAFAQEPHEISRYGGKVNETLKLGLKQAKVVGLFSG 514 +IRTV AF E + +Y K+ K +KQ GL+SG Sbjct: 225 SIRTVVAFTGEKQSMGKYEKKLEIAYKSMVKQ----GLYSG 261
>MSBA_HAEDU (Q7VL52) Lipid A export ATP-binding/permease protein msbA| Length = 582 Score = 70.1 bits (170), Expect = 4e-12 Identities = 41/180 (22%), Positives = 87/180 (48%) Frame = +2 Query: 5 LRAWLFNSASERVVARLRQDLFSHLINQEIAFFDVTRTGELLSRLSEDTQIIKNAATTNL 184 + ++ + S +VV LR+++F HL+ +++FD TG LLSR++ DT+++ ++++ L Sbjct: 83 IASYCLSWVSGKVVMTLRRNIFQHLMYMPVSYFDKNPTGRLLSRVTYDTEMVASSSSYVL 142 Query: 185 SEALRNLTTTAIGLGFMFSTSWKLTLLALVIVPVISVAVRKFGRFLRELSHQTQXXXXXX 364 +R M TSW+L+++ ++ P+I+ + + R LS Q Sbjct: 143 VTIVREGAYLISLFAVMVYTSWQLSIVLFLLAPIIAFLISIVSKRFRILSRNIQNSMGEL 202 Query: 365 XXXXXXXFGAIRTVRAFAQEPHEISRYGGKVNETLKLGLKQAKVVGLFSGGLNAASTLSV 544 + V +F + E +R+ N+ + G+K G+ G + ++L++ Sbjct: 203 TVTTEQMLKGHKVVLSFGGQKVEKARFDRVSNDMRRKGMKIVSADGISDGLVQLIASLAL 262
>MDR20_ARATH (Q9LSJ5) Putative multidrug resistance protein 20 (P-glycoprotein| 18) Length = 1225 Score = 68.9 bits (167), Expect = 8e-12 Identities = 41/179 (22%), Positives = 85/179 (47%), Gaps = 4/179 (2%) Frame = +2 Query: 5 LRAWLFNSASERVVARLRQDLFSHLINQEIAFFD--VTRTGELLSRLSEDTQIIKNAATT 178 + + + ER A++R+ ++ Q++ +FD VT T ++++ +S D+ +I++ + Sbjct: 85 IEGYCWTRTGERQAAKMREKYLKAVLRQDVGYFDLHVTSTSDVITSVSSDSLVIQDFLSE 144 Query: 179 NLSEALRNLTTTAIGLGFMFSTSWKLTLLALVIVPVISVAVRKFGRFLRELSHQTQXXXX 358 L L N + F W+LT++ + ++ + +GR L +S + + Sbjct: 145 KLPNFLMNTSAFVASYIVGFLLLWRLTIVGFPFIILLLIPGLMYGRALIRISMKIREEYN 204 Query: 359 XXXXXXXXXFGAIRTVRAFAQEPHEISRYGGKVNETLKLGLKQ--AKVVGLFSGGLNAA 529 ++RTV AF E I ++ + ++KLGL+Q AK + + S G+ A Sbjct: 205 EAGSIAEQVISSVRTVYAFGSEKKMIEKFSTALQGSVKLGLRQGLAKGIAIGSNGITYA 263 Score = 47.0 bits (110), Expect = 3e-05 Identities = 32/167 (19%), Positives = 70/167 (41%), Gaps = 2/167 (1%) Frame = +2 Query: 20 FNSASERVVARLRQDLFSHLINQEIAFFDVTR--TGELLSRLSEDTQIIKNAATTNLSEA 193 F E + R+R+ + ++ E+ +FD +G + SRL++D ++++ +S Sbjct: 722 FAYMGEYLTKRIRERMLGKILTFEVNWFDKDENSSGAICSRLAKDANMVRSLVGDRMSLL 781 Query: 194 LRNLTTTAIGLGFMFSTSWKLTLLALVIVPVISVAVRKFGRFLRELSHQTQXXXXXXXXX 373 ++ ++ +I SW+ +++ + + PVI V L+ +S Sbjct: 782 VQTISAVSITCAIGLVISWRFSIVMMSVQPVIVVCFYTQRVLLKSMSRNAIKGQDESSKL 841 Query: 374 XXXXFGAIRTVRAFAQEPHEISRYGGKVNETLKLGLKQAKVVGLFSG 514 IRT+ AF+ + I+ K +Q+ + G+ G Sbjct: 842 AAEAVSNIRTITAFSSQERIINLLKMVQEGPRKDSARQSWLAGIMLG 888
>MDR18_ARATH (Q9LSJ8) Multidrug resistance protein 18 (P-glycoprotein 16)| Length = 1228 Score = 68.9 bits (167), Expect = 8e-12 Identities = 41/176 (23%), Positives = 84/176 (47%), Gaps = 4/176 (2%) Frame = +2 Query: 5 LRAWLFNSASERVVARLRQDLFSHLINQEIAFFD--VTRTGELLSRLSEDTQIIKNAATT 178 L + + ER A++R+ ++ Q++ +FD VT T ++++ +S D+ +I++ + Sbjct: 84 LEGYCWTRTGERQAAKMRERYLRAVLRQDVGYFDLHVTSTSDIITSVSSDSLVIQDFLSE 143 Query: 179 NLSEALRNLTTTAIGLGFMFSTSWKLTLLALVIVPVISVAVRKFGRFLRELSHQTQXXXX 358 L L N + F W+LT++ + ++ + +GR L +S + + Sbjct: 144 KLPNILMNASAFVGSYIVGFMLLWRLTIVGFPFIILLLIPGLMYGRALIGISRKIREEYN 203 Query: 359 XXXXXXXXXFGAIRTVRAFAQEPHEISRYGGKVNETLKLGLKQ--AKVVGLFSGGL 520 ++RTV AF E I ++ + ++KLGL+Q AK + + S G+ Sbjct: 204 EAGSIAEQAISSVRTVYAFVSEKKMIEKFSDALQGSVKLGLRQGLAKGIAIGSNGI 259 Score = 49.7 bits (117), Expect = 5e-06 Identities = 27/137 (19%), Positives = 62/137 (45%), Gaps = 2/137 (1%) Frame = +2 Query: 20 FNSASERVVARLRQDLFSHLINQEIAFFDVTR--TGELLSRLSEDTQIIKNAATTNLSEA 193 F+ E + R+R+ + S ++ E+ +FD +G + SRL++D ++++ +S Sbjct: 723 FSYMGEYLTKRIREQMLSKILTFEVNWFDEEENSSGAICSRLAKDANVVRSLVGERMSLL 782 Query: 194 LRNLTTTAIGLGFMFSTSWKLTLLALVIVPVISVAVRKFGRFLRELSHQTQXXXXXXXXX 373 ++ ++T + +W+ T++ + + PVI V L+ +S + Sbjct: 783 VQTISTVMVACTIGLVIAWRFTIVMISVQPVIIVCYYIQRVLLKNMSKKAIIAQDESSKL 842 Query: 374 XXXXFGAIRTVRAFAQE 424 IRT+ F+ + Sbjct: 843 AAEAVSNIRTITTFSSQ 859
>MDR1_CAEEL (P34712) Multidrug resistance protein 1 (EC 3.6.3.44)| (P-glycoprotein A) Length = 1321 Score = 68.6 bits (166), Expect = 1e-11 Identities = 39/170 (22%), Positives = 81/170 (47%) Frame = +2 Query: 32 SERVVARLRQDLFSHLINQEIAFFDVTRTGELLSRLSEDTQIIKNAATTNLSEALRNLTT 211 +E++ RLR++ ++ QEI++FD +G L ++L ++ + +K + A + L+ Sbjct: 164 AEQMNNRLRREFVKSILRQEISWFDTNHSGTLATKLFDNLERVKEGTGDKIGMAFQYLSQ 223 Query: 212 TAIGLGFMFSTSWKLTLLALVIVPVISVAVRKFGRFLRELSHQTQXXXXXXXXXXXXXFG 391 G F+ SW+LTL+ L + P+ ++ + + + + Sbjct: 224 FITGFIVAFTHSWQLTLVMLAVTPIQALCGFAIAKSMSTFAIRETLRYAKAGKVVEETIS 283 Query: 392 AIRTVRAFAQEPHEISRYGGKVNETLKLGLKQAKVVGLFSGGLNAASTLS 541 +IRTV + +E+ RY V E K G+ + +G+ G + A++ +S Sbjct: 284 SIRTVVSLNGLRYELERYSTAVEEAKKAGVLKGLFLGISFGAMQASNFIS 333 Score = 67.0 bits (162), Expect = 3e-11 Identities = 43/172 (25%), Positives = 79/172 (45%), Gaps = 2/172 (1%) Frame = +2 Query: 5 LRAWLFNSASERVVARLRQDLFSHLINQEIAFFDVTR--TGELLSRLSEDTQIIKNAATT 178 L + ASE + LR LF ++++Q I FFD + +G++ +RL+ D ++ A Sbjct: 813 LMTFFMGIASESLTRDLRNKLFRNVLSQHIGFFDSPQNASGKISTRLATDVPNLRTAIDF 872 Query: 179 NLSEALRNLTTTAIGLGFMFSTSWKLTLLALVIVPVISVAVRKFGRFLRELSHQTQXXXX 358 S + L + G+G F W++ LL + I+P+++ GR + ++ Sbjct: 873 RFSTVITTLVSMVAGIGLAFFYGWQMALLIIAILPIVAFGQYLRGRRFTGKNVKSASEFA 932 Query: 359 XXXXXXXXXFGAIRTVRAFAQEPHEISRYGGKVNETLKLGLKQAKVVGLFSG 514 +RTV+A A+E + K++ K +K+A + GL G Sbjct: 933 DSGKIAIEAIENVRTVQALAREDTFYENFCEKLDIPHKEAIKEAFIQGLSYG 984
>TAP1_MOUSE (P21958) Antigen peptide transporter 1 (APT1) (Peptide transporter| TAP1) (ATP-binding cassette sub-family B member 2) (Histocompatibility antigen modifier 1) Length = 724 Score = 68.2 bits (165), Expect = 1e-11 Identities = 44/158 (27%), Positives = 76/158 (48%) Frame = +2 Query: 17 LFNSASERVVARLRQDLFSHLINQEIAFFDVTRTGELLSRLSEDTQIIKNAATTNLSEAL 196 ++N + R+ +++F ++ QE FF G + SR++EDT + + + LS L Sbjct: 224 IYNITMGHMHGRVHREVFRAVLRQETGFFLKNPAGSITSRVTEDTANVCESISDTLSLLL 283 Query: 197 RNLTTTAIGLGFMFSTSWKLTLLALVIVPVISVAVRKFGRFLRELSHQTQXXXXXXXXXX 376 L L FMF S LTL+ L+ +P++ + +K G+ + L+ + Q Sbjct: 284 WYLGRALCLLVFMFWGSPYLTLVTLINLPLLFLLPKKLGKVHQSLAVKVQESLAKSTQVA 343 Query: 377 XXXFGAIRTVRAFAQEPHEISRYGGKVNETLKLGLKQA 490 A+ TVR+FA E E ++ K+ E L K+A Sbjct: 344 LEALSAMPTVRSFANEEGEAQKFRQKLEEMKTLNKKEA 381
>TAP1_RAT (P36370) Antigen peptide transporter 1 (APT1) (Peptide transporter| TAP1) (ATP-binding cassette sub-family B member 2) Length = 725 Score = 67.8 bits (164), Expect = 2e-11 Identities = 42/158 (26%), Positives = 78/158 (49%) Frame = +2 Query: 17 LFNSASERVVARLRQDLFSHLINQEIAFFDVTRTGELLSRLSEDTQIIKNAATTNLSEAL 196 ++N + +R+ ++F +++QE FF TG + SR++EDT + + + L+ L Sbjct: 225 IYNITMGHMHSRVHGEVFRAVLHQETGFFLKNPTGSITSRVTEDTSNVCESISDKLNLFL 284 Query: 197 RNLTTTAIGLGFMFSTSWKLTLLALVIVPVISVAVRKFGRFLRELSHQTQXXXXXXXXXX 376 L L FM S+ LT++ L+ +P++ + R+ G+ + L+ + Q Sbjct: 285 WYLGRGLCLLAFMIWGSFYLTVVTLLSLPLLFLLPRRLGKVYQSLAVKVQESLAKSTQVA 344 Query: 377 XXXFGAIRTVRAFAQEPHEISRYGGKVNETLKLGLKQA 490 A+ TVR+FA E E ++ K+ E L K+A Sbjct: 345 LEALSAMPTVRSFANEEGEAQKFRQKLEEMKPLNKKEA 382
>MDLA_BUCBP (Q89A97) Multidrug resistance-like ATP-binding protein mdlA (EC| 3.6.3.44) Length = 579 Score = 67.8 bits (164), Expect = 2e-11 Identities = 40/169 (23%), Positives = 88/169 (52%), Gaps = 1/169 (0%) Frame = +2 Query: 8 RAWLFNSASERVVARLRQDLFSHLINQEIAFFDVTRTGELLSRLSEDTQIIKNAATTNLS 187 R +LF AS ++ +LR +++++L Q+ F+ +TG+L++R++ D + AA + Sbjct: 78 RLFLFG-ASYKLAIKLRIEIYNYLCQQKNDFYLKHKTGDLIARITNDVDKVVFAAGEGVL 136 Query: 188 EALRNLTT-TAIGLGFMFSTSWKLTLLALVIVPVISVAVRKFGRFLRELSHQTQXXXXXX 364 + +L ++ + + SWKLT+++L+ +P++++ +++FG+ L H Q Sbjct: 137 TLVDSLIMGVSVIIVMITQISWKLTIISLIPMPIMAIIIKRFGKKLYSSYHDAQTTFSHL 196 Query: 365 XXXXXXXFGAIRTVRAFAQEPHEISRYGGKVNETLKLGLKQAKVVGLFS 511 I ++AF E + ++ ++T K +K AK+ F+ Sbjct: 197 NNYAQENLNNIHMIKAFGLENYYSKKFLKIAHKTRKKNIKIAKIDSKFN 245
>MDR21_ARATH (Q9LSJ2) Putative multidrug resistance protein 21 (P-glycoprotein| 22) Length = 1262 Score = 67.0 bits (162), Expect = 3e-11 Identities = 42/179 (23%), Positives = 83/179 (46%), Gaps = 4/179 (2%) Frame = +2 Query: 5 LRAWLFNSASERVVARLRQDLFSHLINQEIAFFD--VTRTGELLSRLSEDTQIIKNAATT 178 + + + ER +R+R+ ++ Q++ +FD VT T ++++ +S DT +I++ + Sbjct: 117 VEGYCWTRTGERQASRMREKYLRAVLRQDVGYFDLHVTSTSDVITSVSSDTLVIQDVLSE 176 Query: 179 NLSEALRNLTTTAIGLGFMFSTSWKLTLLALVIVPVISVAVRKFGRFLRELSHQTQXXXX 358 L L + + F W+LT++ ++ + GR L +S + + Sbjct: 177 KLPNFLMSASAFVASYIVGFIMLWRLTIVGFPFFILLLIPGLMCGRALINISRKIREEYN 236 Query: 359 XXXXXXXXXFGAIRTVRAFAQEPHEISRYGGKVNETLKLGLKQ--AKVVGLFSGGLNAA 529 +RTV AF E IS++ + ++KLGL+Q AK + + S G+ A Sbjct: 237 EAGSIAEQAISLVRTVYAFGSERKMISKFSAALEGSVKLGLRQGIAKGIAIGSNGVTYA 295 Score = 53.9 bits (128), Expect = 3e-07 Identities = 29/142 (20%), Positives = 68/142 (47%), Gaps = 2/142 (1%) Frame = +2 Query: 5 LRAWLFNSASERVVARLRQDLFSHLINQEIAFFDVTR--TGELLSRLSEDTQIIKNAATT 178 ++ + F E + R+R+++ S L+ E+++FD +G + SRL++D ++++ Sbjct: 754 IQQYSFAYMGEYLTKRIRENILSKLLTFEVSWFDEDENSSGSICSRLAKDANVVRSLVGE 813 Query: 179 NLSEALRNLTTTAIGLGFMFSTSWKLTLLALVIVPVISVAVRKFGRFLRELSHQTQXXXX 358 +S ++ ++ ++ + SWKL+++ + I PV+ L+ +S + Sbjct: 814 RVSLLVQTISAVSVACTLGLAISWKLSIVMIAIQPVVVGCFYTQRIVLKSISKKAIKAQD 873 Query: 359 XXXXXXXXXFGAIRTVRAFAQE 424 IRT+ AF+ + Sbjct: 874 ESSKLAAEAVSNIRTITAFSSQ 895
>MSBA_VIBCH (Q9KQW9) Lipid A export ATP-binding/permease protein msbA| Length = 582 Score = 67.0 bits (162), Expect = 3e-11 Identities = 39/147 (26%), Positives = 74/147 (50%) Frame = +2 Query: 32 SERVVARLRQDLFSHLINQEIAFFDVTRTGELLSRLSEDTQIIKNAATTNLSEALRNLTT 211 S VV ++R+ LF+H ++ + FFD TG LLSR++ D++ + A + L +R + Sbjct: 93 SGNVVMQMRRRLFNHFMHMPVRFFDQESTGGLLSRITYDSEQVAGATSRALVSIVREGAS 152 Query: 212 TAIGLGFMFSTSWKLTLLALVIVPVISVAVRKFGRFLRELSHQTQXXXXXXXXXXXXXFG 391 L MF SW+L+L+ +V+ PV++ A+ + R++S Q Sbjct: 153 IIGLLTLMFWNSWQLSLVLIVVAPVVAFAISFVSKRFRKISRNMQTAMGHVTSSAEQMLK 212 Query: 392 AIRTVRAFAQEPHEISRYGGKVNETLK 472 + V ++ + E R+ KV+ +++ Sbjct: 213 GHKVVLSYGGQEVERKRF-DKVSNSMR 238
>MDR3_CAEEL (P34713) Multidrug resistance protein 3 (EC 3.6.3.44)| (P-glycoprotein C) Length = 1268 Score = 66.6 bits (161), Expect = 4e-11 Identities = 37/157 (23%), Positives = 73/157 (46%) Frame = +2 Query: 35 ERVVARLRQDLFSHLINQEIAFFDVTRTGELLSRLSEDTQIIKNAATTNLSEALRNLTTT 214 ER + +R+ ++ Q+ +FD T G L ++S + IK+ + + + T Sbjct: 125 ERRLHCIRKKYLKSVLRQDAKWFDETTIGGLTQKMSSGIEKIKDGIGDKVGVLVGGVATF 184 Query: 215 AIGLGFMFSTSWKLTLLALVIVPVISVAVRKFGRFLRELSHQTQXXXXXXXXXXXXXFGA 394 G+ F W+LTL+ ++ VP+ ++ + L + Sbjct: 185 ISGVSIGFYMCWQLTLVMMITVPLQLGSMYLSAKHLNRATKNEMSAYSNAGGMANEVIAG 244 Query: 395 IRTVRAFAQEPHEISRYGGKVNETLKLGLKQAKVVGL 505 IRTV AF +P EI+RY ++NE ++G+++A ++ + Sbjct: 245 IRTVMAFNAQPFEINRYAHQLNEARRMGIRKAIILAI 281 Score = 55.1 bits (131), Expect = 1e-07 Identities = 32/140 (22%), Positives = 61/140 (43%), Gaps = 2/140 (1%) Frame = +2 Query: 17 LFNSASERVVARLRQDLFSHLINQEIAFFDVTR--TGELLSRLSEDTQIIKNAATTNLSE 190 L A E + RLR D+F +++ Q+ ++FD +R G L SRL+ D ++ A L+E Sbjct: 771 LLGKAGETMSGRLRMDVFRNIMQQDASYFDDSRHNVGSLTSRLATDAPNVQAAIDQRLAE 830 Query: 191 ALRNLTTTAIGLGFMFSTSWKLTLLALVIVPVISVAVRKFGRFLRELSHQTQXXXXXXXX 370 L + + G+G F W + + L ++ V ++L+ + Sbjct: 831 VLTGIVSLFCGVGVAFYYGWNMAPIGLATALLLVVVQSSVAQYLKFRGQRDMDSAIEASR 890 Query: 371 XXXXXFGAIRTVRAFAQEPH 430 +TV+A ++ + Sbjct: 891 LVTESISNWKTVQALTKQEY 910
>MSBA_COXBU (Q83D84) Lipid A export ATP-binding/permease protein msbA| Length = 589 Score = 66.2 bits (160), Expect = 6e-11 Identities = 47/168 (27%), Positives = 75/168 (44%), Gaps = 2/168 (1%) Frame = +2 Query: 5 LRAWLFNSASERVVARLRQDLFSHLINQEIAFFDVTRTGELLSRLSEDTQIIKNAATTNL 184 L + N + +V R+ +FSHL+ F+D +G LLS + + + + A++ L Sbjct: 83 LSTYFINRVARNIVMDFRRAIFSHLLRLPAEFYDRHSSGHLLSTVIYNVEQVAQASSDAL 142 Query: 185 SEALRNLTTTAIGLGFMFSTSWKLTLLALVIVPVISVAVRKFGRFLRELSHQTQXXXXXX 364 L+ + L MF SWKLTL LVI P+I+ +R LR LS Q Sbjct: 143 IITLQASSLVVGLLVVMFLVSWKLTLFFLVITPLIAWVMRVCSARLRHLSTSVQKSVGEV 202 Query: 365 XXXXXXXFGAIRTVRAFAQEPHEIS--RYGGKVNETLKLGLKQAKVVG 502 A + VR + + +E R+ K+N+ +L + VG Sbjct: 203 THIASEAIEAYKIVRLYGGQKYENEKFRHATKLNQQRELKVVVTNSVG 250
>MDR14_ARATH (Q9M3B9) Multidrug resistance protein 14 (P-glycoprotein 20)| Length = 1408 Score = 65.1 bits (157), Expect = 1e-10 Identities = 44/161 (27%), Positives = 70/161 (43%), Gaps = 1/161 (0%) Frame = +2 Query: 35 ERVVARLRQDLFSHLINQEIAFFDV-TRTGELLSRLSEDTQIIKNAATTNLSEALRNLTT 211 ER A +R L+NQ+++FFD G+++S++ D +I++A + + + N+ T Sbjct: 164 ERQTAVIRSKYVQVLLNQDMSFFDTYGNNGDIVSQVLSDVLLIQSALSEKVGNYIHNMAT 223 Query: 212 TAIGLGFMFSTSWKLTLLALVIVPVISVAVRKFGRFLRELSHQTQXXXXXXXXXXXXXFG 391 GL F W++ L+ L P I A FL L+ Q Sbjct: 224 FISGLVIGFVNCWEIALITLATGPFIVAAGGISNIFLHRLAENIQDAYAEAAGIAEQAIS 283 Query: 392 AIRTVRAFAQEPHEISRYGGKVNETLKLGLKQAKVVGLFSG 514 IRT+ AF E Y + TL+ G+ + V GL G Sbjct: 284 YIRTLYAFTNETLAKYSYATSLQATLRYGILISLVQGLGLG 324 Score = 46.6 bits (109), Expect = 5e-05 Identities = 36/172 (20%), Positives = 69/172 (40%), Gaps = 2/172 (1%) Frame = +2 Query: 5 LRAWLFNSASERVVARLRQDLFSHLINQEIAFFDVTRTGE--LLSRLSEDTQIIKNAATT 178 L+ + F E++ R+R+ +FS ++ E+ +FD L RL+ D ++ A + Sbjct: 896 LQHFYFGIMGEKMTERVRRMMFSAMLRNEVGWFDDEENSPDTLSMRLANDATFVRAAFSN 955 Query: 179 NLSEALRNLTTTAIGLGFMFSTSWKLTLLALVIVPVISVAVRKFGRFLRELSHQTQXXXX 358 LS +++ + L W+L L+AL +P+++++ +L S Q Sbjct: 956 RLSIFIQDSFAVIVALLIGLLLGWRLALVALATLPILTLSAIAQKLWLAGFSKGIQEMHR 1015 Query: 359 XXXXXXXXXFGAIRTVRAFAQEPHEISRYGGKVNETLKLGLKQAKVVGLFSG 514 I TV AF + Y ++ L+ +G G Sbjct: 1016 KASLVLEDAVRNIYTVVAFCAGNKVMELYRMQLQRILRQSYLHGMAIGFAFG 1067
>MSBA_VIBVY (Q7MJ07) Lipid A export ATP-binding/permease protein msbA| Length = 583 Score = 65.1 bits (157), Expect = 1e-10 Identities = 37/151 (24%), Positives = 76/151 (50%) Frame = +2 Query: 32 SERVVARLRQDLFSHLINQEIAFFDVTRTGELLSRLSEDTQIIKNAATTNLSEALRNLTT 211 S VV ++R+ +F+H + +++FD ++G LLSR++ D++ + A + L +R T+ Sbjct: 93 SGNVVMQVRRMVFNHYMQMPVSYFDKEKSGSLLSRITYDSEQVSAATSQALVSIVREGTS 152 Query: 212 TAIGLGFMFSTSWKLTLLALVIVPVISVAVRKFGRFLRELSHQTQXXXXXXXXXXXXXFG 391 L MF SW+L+L+ +++ PV++ A+ + R++S Q Sbjct: 153 IIGLLVLMFYNSWQLSLVLILVAPVVAWAIGFVSKRFRKISKNMQTTMGIVTSSAEQMLK 212 Query: 392 AIRTVRAFAQEPHEISRYGGKVNETLKLGLK 484 + V ++ + E SR+ N+ + +K Sbjct: 213 GHKVVLSYGGQEVEKSRFDVVSNQMRQQSMK 243
>MSBA_VIBVU (Q8DAV2) Lipid A export ATP-binding/permease protein msbA| Length = 583 Score = 65.1 bits (157), Expect = 1e-10 Identities = 37/151 (24%), Positives = 76/151 (50%) Frame = +2 Query: 32 SERVVARLRQDLFSHLINQEIAFFDVTRTGELLSRLSEDTQIIKNAATTNLSEALRNLTT 211 S VV ++R+ +F+H + +++FD ++G LLSR++ D++ + A + L +R T+ Sbjct: 93 SGNVVMQVRRMVFNHYMQMPVSYFDKEKSGSLLSRITYDSEQVSAATSQALVSIVREGTS 152 Query: 212 TAIGLGFMFSTSWKLTLLALVIVPVISVAVRKFGRFLRELSHQTQXXXXXXXXXXXXXFG 391 L MF SW+L+L+ +++ PV++ A+ + R++S Q Sbjct: 153 IIGLLVLMFYNSWQLSLVLILVAPVVAWAIGFVSKRFRKISKNMQTTMGIVTSSAEQMLK 212 Query: 392 AIRTVRAFAQEPHEISRYGGKVNETLKLGLK 484 + V ++ + E SR+ N+ + +K Sbjct: 213 GHKVVLSYGGQEVEKSRFDVVSNQMRQQSMK 243
>MSBA_RALSO (Q8XXB6) Lipid A export ATP-binding/permease protein msbA| Length = 592 Score = 64.7 bits (156), Expect = 2e-10 Identities = 42/174 (24%), Positives = 72/174 (41%) Frame = +2 Query: 14 WLFNSASERVVARLRQDLFSHLINQEIAFFDVTRTGELLSRLSEDTQIIKNAATTNLSEA 193 + + S +V+ LR +F L+ AF+ L++ + + + T Sbjct: 94 YFLSLVSNKVLLNLRMKMFERLLQAPAAFYQRNTAASLINAVIFEVNQVLQVLTGVFITL 153 Query: 194 LRNLTTTAIGLGFMFSTSWKLTLLALVIVPVISVAVRKFGRFLRELSHQTQXXXXXXXXX 373 +R+ T L F+F T+W+LTL+ VI+PVI + + R LR L+ + Q Sbjct: 154 VRDSMTVLALLIFLFYTNWRLTLVVAVILPVIGFLMSRINRRLRSLNREHQNLTNEAAYV 213 Query: 374 XXXXFGAIRTVRAFAQEPHEISRYGGKVNETLKLGLKQAKVVGLFSGGLNAAST 535 G + V+ E +E R+ N ++ A +GGLN T Sbjct: 214 VEEAAGGYKVVKLHGGEAYESRRFNAMTNRLRGYAMRMA-----VAGGLNQPVT 262
>MDR6_ARATH (Q8LPT1) Multidrug resistance protein 6 (P-glycoprotein 6)| Length = 1407 Score = 64.3 bits (155), Expect = 2e-10 Identities = 43/161 (26%), Positives = 70/161 (43%), Gaps = 1/161 (0%) Frame = +2 Query: 35 ERVVARLRQDLFSHLINQEIAFFDV-TRTGELLSRLSEDTQIIKNAATTNLSEALRNLTT 211 ER A +R L+NQ+++FFD G+++S++ D +I++A + + + N+ T Sbjct: 162 ERQTAVIRSKYVQVLLNQDMSFFDTYGNNGDIVSQVLSDVLLIQSALSEKVGNYIHNMAT 221 Query: 212 TAIGLGFMFSTSWKLTLLALVIVPVISVAVRKFGRFLRELSHQTQXXXXXXXXXXXXXFG 391 GL F W++ L+ L P I A FL L+ Q Sbjct: 222 FISGLIIGFVNCWEIALITLATGPFIVAAGGISNIFLHRLAENIQDAYAEAASIAEQAVS 281 Query: 392 AIRTVRAFAQEPHEISRYGGKVNETLKLGLKQAKVVGLFSG 514 +RT+ AF E Y + TL+ G+ + V GL G Sbjct: 282 YVRTLYAFTNETLAKYSYATSLQATLRYGILISLVQGLGLG 322 Score = 47.0 bits (110), Expect = 3e-05 Identities = 39/172 (22%), Positives = 71/172 (41%), Gaps = 2/172 (1%) Frame = +2 Query: 5 LRAWLFNSASERVVARLRQDLFSHLINQEIAFFDVTRTGE--LLSRLSEDTQIIKNAATT 178 L+ + F E++ R+R+ +FS ++ E+ ++D L RL+ D ++ A + Sbjct: 895 LQHFYFGIMGEKMTERVRRMMFSAMLRNEVGWYDEEENSPDTLSMRLANDATFVRAAFSN 954 Query: 179 NLSEALRNLTTTAIGLGFMFSTSWKLTLLALVIVPVISVAVRKFGRFLRELSHQTQXXXX 358 LS +++ + + W+L L+AL +PV++++ +L S Q Sbjct: 955 RLSIFIQDSFAVIVAILIGLLLGWRLALVALATLPVLTLSAIAQKLWLAGFSKGIQEMHR 1014 Query: 359 XXXXXXXXXFGAIRTVRAFAQEPHEISRYGGKVNETLKLGLKQAKVVGLFSG 514 I TV AF G KV E +L L++ F G Sbjct: 1015 KASLVLEDAVRNIYTVVAFCA--------GNKVMELYRLQLQRILRQSFFHG 1058
>MSBA_PSEAE (Q9HUG8) Lipid A export ATP-binding/permease protein msbA| Length = 603 Score = 64.3 bits (155), Expect = 2e-10 Identities = 40/135 (29%), Positives = 64/135 (47%) Frame = +2 Query: 41 VVARLRQDLFSHLINQEIAFFDVTRTGELLSRLSEDTQIIKNAATTNLSEALRNLTTTAI 220 +V LR LF+ L+ +FD +G L+SR++ + ++ AAT + +R T Sbjct: 112 LVHDLRVALFNKLLVLPNRYFDTHSSGHLISRITFNVTMVTGAATDAIKVVIREGLTVVF 171 Query: 221 GLGFMFSTSWKLTLLALVIVPVISVAVRKFGRFLRELSHQTQXXXXXXXXXXXXXFGAIR 400 ++ +WKLTL+ L I+PVI+V V R R+ S + Q R Sbjct: 172 LFLYLLWMNWKLTLVMLAILPVIAVMVTTASRKFRKQSKKIQVAMGDVTHVASETIQGYR 231 Query: 401 TVRAFAQEPHEISRY 445 VR+F E +E R+ Sbjct: 232 VVRSFGGEAYEEKRF 246
>MDR1_ARATH (Q9ZR72) Multidrug resistance protein 1 (P-glycoprotein 1) (AtPgp1)| Length = 1286 Score = 64.3 bits (155), Expect = 2e-10 Identities = 43/171 (25%), Positives = 75/171 (43%), Gaps = 1/171 (0%) Frame = +2 Query: 5 LRAWLFNSASERVVARLRQDLFSHLINQEIAFFDV-TRTGELLSRLSEDTQIIKNAATTN 181 + W+++ ER ++R +NQ+I FFD RT +++ ++ D ++++A + Sbjct: 108 ISCWMWSG--ERQTTKMRIKYLEAALNQDIQFFDTEVRTSDVVFAINTDAVMVQDAISEK 165 Query: 182 LSEALRNLTTTAIGLGFMFSTSWKLTLLALVIVPVISVAVRKFGRFLRELSHQTQXXXXX 361 L + + T G F+ W+L L+ L +VP+I+V L +LS+++Q Sbjct: 166 LGNFIHYMATFVSGFIVGFTAVWQLALVTLAVVPLIAVIGGIHTTTLSKLSNKSQESLSQ 225 Query: 362 XXXXXXXXFGAIRTVRAFAQEPHEISRYGGKVNETLKLGLKQAKVVGLFSG 514 IR V AF E Y + KLG K G+ G Sbjct: 226 AGNIVEQTVVQIRVVMAFVGESRASQAYSSALKIAQKLGYKTGLAKGMGLG 276 Score = 52.4 bits (124), Expect = 8e-07 Identities = 33/158 (20%), Positives = 65/158 (41%), Gaps = 2/158 (1%) Frame = +2 Query: 35 ERVVARLRQDLFSHLINQEIAFFDV--TRTGELLSRLSEDTQIIKNAATTNLSEALRNLT 208 E + R+R+ + S ++ E+A+FD + + +RL+ D +++A +S ++N Sbjct: 770 ENLTKRVREKMLSAVLKNEMAWFDQEENESARIAARLALDANNVRSAIGDRISVIVQNTA 829 Query: 209 TTAIGLGFMFSTSWKLTLLALVIVPVISVAVRKFGRFLRELSHQTQXXXXXXXXXXXXXF 388 + F W+L L+ + + PV+ A F+ S + Sbjct: 830 LMLVACTAGFVLQWRLALVLVAVFPVVVAATVLQKMFMTGFSGDLEAAHAKGTQLAGEAI 889 Query: 389 GAIRTVRAFAQEPHEISRYGGKVNETLKLGLKQAKVVG 502 +RTV AF E + Y + LK + ++ G Sbjct: 890 ANVRTVAAFNSEAKIVRLYTANLEPPLKRCFWKGQIAG 927
>YFIC_BACSU (P54719) Hypothetical ABC transporter ATP-binding protein yfiC| Length = 604 Score = 64.3 bits (155), Expect = 2e-10 Identities = 47/185 (25%), Positives = 86/185 (46%), Gaps = 5/185 (2%) Frame = +2 Query: 2 ALRAWLFN----SASERVVARLRQDLFSHLINQEIAFFDVTRTGELLSRLSEDTQIIKNA 169 +L W N + S+ V R+R +LF+HL I FFD R GEL+SR++ D + + + Sbjct: 101 SLSLWFQNYWMITISQGTVFRMRSELFTHLHELPIPFFDKQRHGELMSRVTNDIENVSST 160 Query: 170 ATTNLSEALRNLTTTAIGLGFMFSTSWKLTLLALVIVPVISVAVRKFGRFLRELSHQTQX 349 T++ + L ++ T + M S LTL+ L I+PV++ +++ +L + Q Sbjct: 161 LNTSVIQILSSVITFVGTIAVMLYMSPLLTLITLTIIPVMAASLKWITNRTGKLFKEQQK 220 Query: 350 XXXXXXXXXXXXFGAIRTVRAFAQEPHEISRYGGKVNETLKL-GLKQAKVVGLFSGGLNA 526 + ++A+++E + + K N LK G + G +N+ Sbjct: 221 NLGDLNGYIEESVSGAKVIKAYSREKQITAEFLEK-NAALKTSGFWAQTISGFIPKVMNS 279 Query: 527 ASTLS 541 + LS Sbjct: 280 LNNLS 284
>MSBA_BURPS (Q63VX7) Lipid A export ATP-binding/permease protein msbA| Length = 596 Score = 64.3 bits (155), Expect = 2e-10 Identities = 44/185 (23%), Positives = 79/185 (42%), Gaps = 8/185 (4%) Frame = +2 Query: 14 WLFNSASERVVARLRQDLFSHLINQEIAFFDVTRTGELLSRLSEDTQIIKNAATTNLSEA 193 +L S R++ LR +F +I+ ++FF +++ + + + + Sbjct: 98 YLLQYVSNRILLDLRIQMFERMIHTGVSFFQRETASTVINAVVFEVNQVLSVLMGVTITL 157 Query: 194 LRNLTTTAIGLGFMFSTSWKLTLLALVIVPVISVAVRKFGRFLRELSHQTQXXXXXXXXX 373 +R+ T LG++F +W+LTL+ +++P I V K R LR L+ + Q Sbjct: 158 VRDSLTVVFLLGYLFYLNWRLTLIVAILLPCIGWLVGKINRRLRRLNREHQTLTNQLAYI 217 Query: 374 XXXXFGAIRTVRAFAQEPHEISRY--------GGKVNETLKLGLKQAKVVGLFSGGLNAA 529 G + V+ EP+EI R+ G + T+ GL Q L S L Sbjct: 218 VEETVGGYKVVKVHNGEPYEIGRFNELSRKLRGYSMRMTVSGGLAQPLTQFLASIALAVV 277 Query: 530 STLSV 544 T++V Sbjct: 278 LTIAV 282
>MSBA_BURMA (Q62IG3) Lipid A export ATP-binding/permease protein msbA| Length = 596 Score = 64.3 bits (155), Expect = 2e-10 Identities = 44/185 (23%), Positives = 79/185 (42%), Gaps = 8/185 (4%) Frame = +2 Query: 14 WLFNSASERVVARLRQDLFSHLINQEIAFFDVTRTGELLSRLSEDTQIIKNAATTNLSEA 193 +L S R++ LR +F +I+ ++FF +++ + + + + Sbjct: 98 YLLQYVSNRILLDLRIQMFERMIHTGVSFFQRETASTVINAVVFEVNQVLSVLMGVTITL 157 Query: 194 LRNLTTTAIGLGFMFSTSWKLTLLALVIVPVISVAVRKFGRFLRELSHQTQXXXXXXXXX 373 +R+ T LG++F +W+LTL+ +++P I V K R LR L+ + Q Sbjct: 158 VRDSLTVVFLLGYLFYLNWRLTLIVAILLPCIGWLVGKINRRLRRLNREHQTLTNQLAYI 217 Query: 374 XXXXFGAIRTVRAFAQEPHEISRY--------GGKVNETLKLGLKQAKVVGLFSGGLNAA 529 G + V+ EP+EI R+ G + T+ GL Q L S L Sbjct: 218 VEETVGGYKVVKVHNGEPYEIGRFNELSRKLRGYSMRMTVSGGLAQPLTQFLASIALAVV 277 Query: 530 STLSV 544 T++V Sbjct: 278 LTIAV 282
>ABCBB_RABIT (Q9N0V3) Bile salt export pump (ATP-binding cassette sub-family B| member 11) (Sister of P-glycoprotein) Length = 1321 Score = 63.9 bits (154), Expect = 3e-10 Identities = 41/172 (23%), Positives = 77/172 (44%), Gaps = 2/172 (1%) Frame = +2 Query: 5 LRAWLFNSASERVVARLRQDLFSHLINQEIAFFDVTRT--GELLSRLSEDTQIIKNAATT 178 L+ + F + E + RLR+ F ++ Q+I +FD R G L +RL+ D ++ A + Sbjct: 815 LQGYTFAKSGELLTKRLRKFGFRAMLGQDIGWFDDLRNSPGALTTRLATDASQVQGATGS 874 Query: 179 NLSEALRNLTTTAIGLGFMFSTSWKLTLLALVIVPVISVAVRKFGRFLRELSHQTQXXXX 358 + + + T + + F SWKLTL + P ++++ + L + + + Sbjct: 875 QIGMMVNSFTNVTVAMIIAFLFSWKLTLGIVCFFPFLALSGALQTKMLTGFASRDKQALE 934 Query: 359 XXXXXXXXXFGAIRTVRAFAQEPHEISRYGGKVNETLKLGLKQAKVVGLFSG 514 IRTV +E I + ++ + K+ +K+A V GL G Sbjct: 935 KAGQITSEALSNIRTVAGIGKERKFIETFEAELEKPYKMAIKKANVYGLCFG 986 Score = 63.2 bits (152), Expect = 5e-10 Identities = 37/162 (22%), Positives = 73/162 (45%) Frame = +2 Query: 29 ASERVVARLRQDLFSHLINQEIAFFDVTRTGELLSRLSEDTQIIKNAATTNLSEALRNLT 208 A+ + ++R+ F ++ I + D G+L + S D I +++ L+ ++ +T Sbjct: 166 AAAHQIQKMRKSYFRKIMRMGIGWVDCNSVGKLNTPFSVDFNKINDSSADQLAIFIQGMT 225 Query: 209 TTAIGLGFMFSTSWKLTLLALVIVPVISVAVRKFGRFLRELSHQTQXXXXXXXXXXXXXF 388 + G FS WKLTL+ + + P+I + G + + + Sbjct: 226 SPIFGFLVGFSQWWKLTLVIISVSPLIGLGAAIIGLSVSKFTDYELKAYAKAGSVADEVI 285 Query: 389 GAIRTVRAFAQEPHEISRYGGKVNETLKLGLKQAKVVGLFSG 514 ++RTV AF E E+ RY + + G+++ V+G F+G Sbjct: 286 SSMRTVAAFGGEKKEVERYEKNLVFAQRWGIRKGIVMGFFTG 327
>MSBA_PSEPK (Q88D92) Lipid A export ATP-binding/permease protein msbA| Length = 602 Score = 63.9 bits (154), Expect = 3e-10 Identities = 41/157 (26%), Positives = 70/157 (44%) Frame = +2 Query: 41 VVARLRQDLFSHLINQEIAFFDVTRTGELLSRLSEDTQIIKNAATTNLSEALRNLTTTAI 220 +V LR LF+ L+ +FD +G L+SR++ + ++ AAT + +R T Sbjct: 111 LVHDLRVALFNKLLVLPNRYFDNHNSGHLISRITFNVTMVTGAATDAIKVVIREGLTVVF 170 Query: 221 GLGFMFSTSWKLTLLALVIVPVISVAVRKFGRFLRELSHQTQXXXXXXXXXXXXXFGAIR 400 ++ +W LTL+ + I+PVI+V V + R+ S + Q R Sbjct: 171 LFAYLLWMNWHLTLVMVAILPVIAVMVSIASKKFRKQSKKIQVAMGDVTHVASETIQGYR 230 Query: 401 TVRAFAQEPHEISRYGGKVNETLKLGLKQAKVVGLFS 511 VR+F E +E R+G L+ K L++ Sbjct: 231 VVRSFGGEAYEQQRFGQASQSNTDKQLRMTKTGSLYT 267
>MSBA_METCA (Q60AA3) Lipid A export ATP-binding/permease protein msbA| Length = 601 Score = 63.5 bits (153), Expect = 4e-10 Identities = 45/180 (25%), Positives = 81/180 (45%) Frame = +2 Query: 5 LRAWLFNSASERVVARLRQDLFSHLINQEIAFFDVTRTGELLSRLSEDTQIIKNAATTNL 184 L + S RV+A LR+D+F L+N +F+D G+LLS+L +T+ + + + Sbjct: 89 LSEYCSGSVGRRVIADLRRDIFDQLLNLPCSFYDNASGGQLLSKLLYNTEQVSASLQQGI 148 Query: 185 SEALRNLTTTAIGLGFMFSTSWKLTLLALVIVPVISVAVRKFGRFLRELSHQTQXXXXXX 364 +R T + M + L+L+ LV+ PV+ ++VR + R LS + Q Sbjct: 149 ITCIREGFTVIGLMALMVYQNPVLSLVFLVLGPVLGLSVRFVSKRFRRLSMRIQESMGKV 208 Query: 365 XXXXXXXFGAIRTVRAFAQEPHEISRYGGKVNETLKLGLKQAKVVGLFSGGLNAASTLSV 544 A R V+ F + +E +++ + + K +K L G ++ S V Sbjct: 209 SHVTQEVIDAQRIVKVFNGKDYEAAKFATENDRNQKRQMKLIATDALGGGVIHLISVAGV 268
>Y288_THEMA (Q9WYC4) Hypothetical ABC transporter ATP-binding protein TM0288| Length = 598 Score = 62.8 bits (151), Expect = 6e-10 Identities = 45/179 (25%), Positives = 83/179 (46%), Gaps = 1/179 (0%) Frame = +2 Query: 5 LRAWLFNSASERVVARLRQDLFSHLINQEIAFFDVTRTGELLSRLSEDTQIIKNAATTNL 184 L+ + + S+ VV RLR++LF L + FFD T G+++SR+ D I N ++ Sbjct: 96 LQGKIMLTLSQDVVFRLRKELFEKLQRVPVGFFDRTPHGDIISRVINDVDNINNVLGNSI 155 Query: 185 SEALRNLTTTAIGLGFMFSTSWKLTLLALVIVPVISVAVRKFGRFLRELSHQTQXXXXXX 364 + + T A + MF + L+L+ L IVP+ + + R+ ++ Q Sbjct: 156 IQFFSGIVTLAGAVIMMFRVNVILSLVTLSIVPLTVLITQIVSSQTRKYFYENQRVLGQL 215 Query: 365 XXXXXXXFGAIRTVRAFAQEPHEISRYGGKVNETL-KLGLKQAKVVGLFSGGLNAASTL 538 + ++ F +E E+ ++ +VNE+L K+G K G+ +N + L Sbjct: 216 NGIIEEDISGLTVIKLFTREEKEMEKF-DRVNESLRKVGTKAQIFSGVLPPLMNMVNNL 273
>TAGC_DICDI (Q23868) Prestalk-specific protein tagC precursor (EC 3.4.21.-)| Length = 1743 Score = 62.8 bits (151), Expect = 6e-10 Identities = 37/156 (23%), Positives = 70/156 (44%) Frame = +2 Query: 5 LRAWLFNSASERVVARLRQDLFSHLINQEIAFFDVTRTGELLSRLSEDTQIIKNAATTNL 184 + +W+ +E++V RL+ +F LI Q++ FF L++ L DT ++++A T L Sbjct: 1088 ISSWISGIVNEKMVMRLQNKVFRALIAQDMGFFQKNNAAILMNVLISDTPMLRSALTGIL 1147 Query: 185 SEALRNLTTTAIGLGFMFSTSWKLTLLALVIVPVISVAVRKFGRFLRELSHQTQXXXXXX 364 L L F+F+ SWKL+L+ VPV++ + +F + L+ Sbjct: 1148 LSIATGLCKFVGSLVFIFTISWKLSLVFFATVPVLAFITQIQSQFTKRLTRALLFYNSKA 1207 Query: 365 XXXXXXXFGAIRTVRAFAQEPHEISRYGGKVNETLK 472 + V + ++ EI +Y +N + Sbjct: 1208 SQHGQESMVNMHVVTNYCRQDKEIIKYTDNLNNVFQ 1243
>MDLB_BUCAP (Q8K984) Multidrug resistance-like ATP-binding protein mdlB (EC| 3.6.3.44) Length = 580 Score = 62.4 bits (150), Expect = 8e-10 Identities = 34/153 (22%), Positives = 72/153 (47%) Frame = +2 Query: 17 LFNSASERVVARLRQDLFSHLINQEIAFFDVTRTGELLSRLSEDTQIIKNAATTNLSEAL 196 LFN + +V +LR D+ +NQ I+ FD G+++S+++ DT++IK T Sbjct: 88 LFNKIAVGIVNKLRNDVMKAALNQPISEFDSQPIGQMISKVTNDTEVIKELYDTVGPTFF 147 Query: 197 RNLTTTAIGLGFMFSTSWKLTLLALVIVPVISVAVRKFGRFLRELSHQTQXXXXXXXXXX 376 R++T I L MF+ W + ++ + I+P++ + + + + L + Sbjct: 148 RSITLIIIILFAMFTLEWHMAIITIFIIPLVIIVMSIYQYYSTPLLRNVRYYVANINNKF 207 Query: 377 XXXFGAIRTVRAFAQEPHEISRYGGKVNETLKL 475 + ++ F Q+ +R+ + E+ +L Sbjct: 208 NETINGMNVIQQFRQQ----TRFENNIKESSEL 236
>MDLA_ECOLI (P77265) Multidrug resistance-like ATP-binding protein mdlA (EC| 3.6.3.44) Length = 590 Score = 62.4 bits (150), Expect = 8e-10 Identities = 43/166 (25%), Positives = 77/166 (46%), Gaps = 2/166 (1%) Frame = +2 Query: 17 LFNSASERVVARLRQDLFSHLINQEIAFFDVTRTGELLSRLSEDTQIIKNAATTNLSEAL 196 L AS ++ LR+D + L Q F+ RTG+L++R + D + AA + + Sbjct: 80 LLFGASYQLAVELREDYYRQLSRQHPEFYLRHRTGDLMARATNDVDRVVFAAGEGVLTLV 139 Query: 197 RNLTTTAIGLGFMFST--SWKLTLLALVIVPVISVAVRKFGRFLRELSHQTQXXXXXXXX 370 +L L M ST SW+LTL +L+ +PV+++ +++ G L E Q Sbjct: 140 DSLVMGCAVL-IMMSTQISWQLTLFSLLPMPVMAIMIKRNGDALHERFKLAQAAFSSLND 198 Query: 371 XXXXXFGAIRTVRAFAQEPHEISRYGGKVNETLKLGLKQAKVVGLF 508 +IR ++AF E + + + +T K ++ A++ F Sbjct: 199 RTQESLTSIRMIKAFGLEDRQSALFAADAEDTGKKNMRVARIDARF 244
>MSBA_FRANO (Q47908) Lipid A export ATP-binding/permease protein msbA| Length = 593 Score = 62.0 bits (149), Expect = 1e-09 Identities = 36/175 (20%), Positives = 81/175 (46%) Frame = +2 Query: 14 WLFNSASERVVARLRQDLFSHLINQEIAFFDVTRTGELLSRLSEDTQIIKNAATTNLSEA 193 + S ++VV + R+D++ L++ +FFD TG+++SRL + + A +T + Sbjct: 91 YFIGSLGQKVVYKFRKDIYKRLMDLPASFFDKHSTGQIISRLLYNVDQVTEATSTAIITV 150 Query: 194 LRNLTTTAIGLGFMFSTSWKLTLLALVIVPVISVAVRKFGRFLRELSHQTQXXXXXXXXX 373 +++ T + MF +SW+L+L +V+ P + + + + R LS TQ Sbjct: 151 VQDGTFVIGLIVVMFVSSWQLSLFLIVVGPFLGLFISIINKKFRNLSRNTQSSMGNVTHT 210 Query: 374 XXXXFGAIRTVRAFAQEPHEISRYGGKVNETLKLGLKQAKVVGLFSGGLNAASTL 538 + +R F + + +++ ++ T ++ + L S + ++L Sbjct: 211 AEETIRNYKEIRIFGAQQKQQNKFFKNLDYTYSQQIRTIALDALTSPVIQIIASL 265
>HEPA_ANASP (P22638) Heterocyst differentiation ATP-binding protein hepA| Length = 607 Score = 61.6 bits (148), Expect = 1e-09 Identities = 37/153 (24%), Positives = 72/153 (47%) Frame = +2 Query: 26 SASERVVARLRQDLFSHLINQEIAFFDVTRTGELLSRLSEDTQIIKNAATTNLSEALRNL 205 SA + RL + +F L +++F TR+GEL++ ++ + + IK + L+ L + Sbjct: 115 SAQLNLADRLHKQIFEQLQALRLSYFAQTRSGELINTITTEIERIKQGFS-GLAFVLTRI 173 Query: 206 TTTAIGLGFMFSTSWKLTLLALVIVPVISVAVRKFGRFLRELSHQTQXXXXXXXXXXXXX 385 T + MFS SW+L++++++I +++V + + +RE S Sbjct: 174 MTVCVYFVVMFSISWQLSIISVLIFLLLAVGLSTLNKRVRETSFGISHANAQFTAVAVEF 233 Query: 386 FGAIRTVRAFAQEPHEISRYGGKVNETLKLGLK 484 IRT++AF + E R+ L +K Sbjct: 234 INGIRTIQAFGTQEFERQRFYKASTNQLNAAIK 266
>MDLA_BUCAI (P57551) Multidrug resistance-like ATP-binding protein mdlA (EC| 3.6.3.44) Length = 589 Score = 61.6 bits (148), Expect = 1e-09 Identities = 41/166 (24%), Positives = 80/166 (48%), Gaps = 2/166 (1%) Frame = +2 Query: 17 LFNSASERVVARLRQDLFSHLINQEIAFFDVTRTGELLSRLSEDTQIIKNAATTNLSEAL 196 L AS ++ LR +++L Q FF RTG+L++R + D + AA + + Sbjct: 80 LLFGASYQLATELRVKFYTYLSQQSQIFFLKNRTGDLIARATNDVDRVVFAAGEGVLTLV 139 Query: 197 RNLTTTAIGLGFMFST--SWKLTLLALVIVPVISVAVRKFGRFLRELSHQTQXXXXXXXX 370 +L + + ST S+ LT+++L+ +P++++ ++K+G+ L E Q Sbjct: 140 DSLVM-GFSVLIVMSTQISFLLTIISLIPMPIMAILIKKYGKELHETFRHAQISFSLLNN 198 Query: 371 XXXXXFGAIRTVRAFAQEPHEISRYGGKVNETLKLGLKQAKVVGLF 508 +IR +RAF E ++ +++ T K ++ AK+ F Sbjct: 199 QTQEILTSIRMIRAFGLEKNQSNKFNIITRNTGKKNMEVAKIDARF 244
>MDR65_DROME (Q00748) Multidrug resistance protein homolog 65 (EC 3.6.3.44)| (P-glycoprotein 65) Length = 1302 Score = 60.8 bits (146), Expect = 2e-09 Identities = 42/166 (25%), Positives = 72/166 (43%) Frame = +2 Query: 17 LFNSASERVVARLRQDLFSHLINQEIAFFDVTRTGELLSRLSEDTQIIKNAATTNLSEAL 196 +FN + R V R+R LFS +I Q+I + D+ + +D + I++ + + + Sbjct: 141 VFNMVALRQVTRMRIKLFSSVIRQDIGWHDLASKQNFTQSMVDDVEKIRDGISEKVGHFV 200 Query: 197 RNLTTTAIGLGFMFSTSWKLTLLALVIVPVISVAVRKFGRFLRELSHQTQXXXXXXXXXX 376 + I + FS WKLTL +P++ + +F +L+ + Q Sbjct: 201 YLVVGFIITVAISFSYGWKLTLAVSSYIPLVILLNYYVAKFQGKLTAREQESYAGAGNLA 260 Query: 377 XXXFGAIRTVRAFAQEPHEISRYGGKVNETLKLGLKQAKVVGLFSG 514 +IRTV +F E E+ RY L K ++ G FSG Sbjct: 261 EEILSSIRTVVSFGGEKSEVQRY----ENFLVPARKASQWKGAFSG 302 Score = 51.6 bits (122), Expect = 1e-06 Identities = 42/178 (23%), Positives = 76/178 (42%), Gaps = 2/178 (1%) Frame = +2 Query: 5 LRAWLFNSASERVVARLRQDLFSHLINQEIAFFD--VTRTGELLSRLSEDTQIIKNAATT 178 L+ +LFN A + R+R F+ ++NQE+ +FD G L +RLS + I+ A Sbjct: 792 LQTYLFNYAGIWLTTRMRAMTFNAMVNQEVGWFDDENNSVGALSARLSGEAVDIQGAIGY 851 Query: 179 NLSEALRNLTTTAIGLGFMFSTSWKLTLLALVIVPVISVAVRKFGRFLRELSHQTQXXXX 358 LS ++ L+ + +WKL LL L P+I +V + + + + Sbjct: 852 PLSGMIQALSNFISSVSVAMYYNWKLALLCLANCPIIVGSVILEAKMMSNAVVREKQVIE 911 Query: 359 XXXXXXXXXFGAIRTVRAFAQEPHEISRYGGKVNETLKLGLKQAKVVGLFSGGLNAAS 532 IRTV +E I Y ++ L ++ + G+ + + A++ Sbjct: 912 EACRIATESITNIRTVAGLRREADVIREYTEEIQRVEVLIRQKLRWRGVLNSTMQASA 969
>TAGB_DICDI (P54683) Prestalk-specific protein tagB precursor (EC 3.4.21.-)| Length = 1905 Score = 60.8 bits (146), Expect = 2e-09 Identities = 34/149 (22%), Positives = 69/149 (46%) Frame = +2 Query: 11 AWLFNSASERVVARLRQDLFSHLINQEIAFFDVTRTGELLSRLSEDTQIIKNAATTNLSE 190 +W+ +E++V RL+ +F LI Q++ FF + L++ L DT ++++A T L Sbjct: 1139 SWISGIVNEKMVMRLQNKVFRALIAQDMGFFQRNNSALLMNVLIVDTPMLRSALTGILLS 1198 Query: 191 ALRNLTTTAIGLGFMFSTSWKLTLLALVIVPVISVAVRKFGRFLRELSHQTQXXXXXXXX 370 + L F+F+ SWKL+L VP++ + + +F + L+ Q Sbjct: 1199 IATGVCKLVGSLVFIFTISWKLSLAFFAAVPILGLVTQIQSQFTKRLTRQLLFHNSKASQ 1258 Query: 371 XXXXXFGAIRTVRAFAQEPHEISRYGGKV 457 + V + ++ E+ +Y ++ Sbjct: 1259 HGTESLTNMHVVTNYCKQEKEMVKYSDQL 1287
>MSBA_BLOFL (Q7VR44) Lipid A export ATP-binding/permease protein msbA| Length = 583 Score = 60.5 bits (145), Expect = 3e-09 Identities = 38/172 (22%), Positives = 84/172 (48%), Gaps = 1/172 (0%) Frame = +2 Query: 32 SERVVARLRQDLFSHLINQEIAFFDVTRTGELLSRLSEDTQIIKNAATTNLSEALRNLTT 211 S +VV +R+ LF+H++N ++FF T L+SR++ D + ++++ L +R Sbjct: 95 SGKVVMHIRRLLFNHIMNMPVSFFIEQSTATLMSRITYDADQVASSSSGALITIIRE-GA 153 Query: 212 TAIGLG-FMFSTSWKLTLLALVIVPVISVAVRKFGRFLRELSHQTQXXXXXXXXXXXXXF 388 + +GL MF SW+L+L+ ++I+P+IS+ ++ +++ + Q Sbjct: 154 SVVGLCIMMFYYSWQLSLVLILIMPIISIIIKLVSNKFKDIGKKIQNSMSQLVNSVEQML 213 Query: 389 GAIRTVRAFAQEPHEISRYGGKVNETLKLGLKQAKVVGLFSGGLNAASTLSV 544 + V F + E +R+ N + +K + +F + ++L++ Sbjct: 214 KGHKEVLIFGGQHLEQNRFNYLSNRMRQYTMKMVQTSSVFEPLIQFVASLAL 265
>MSBA_VIBPA (Q87R16) Lipid A export ATP-binding/permease protein msbA| Length = 582 Score = 60.5 bits (145), Expect = 3e-09 Identities = 35/151 (23%), Positives = 71/151 (47%) Frame = +2 Query: 32 SERVVARLRQDLFSHLINQEIAFFDVTRTGELLSRLSEDTQIIKNAATTNLSEALRNLTT 211 S VV +R+ +F+H ++ +++FD +TG LLSR++ D++ + A + L +R + Sbjct: 93 SGNVVMLVRRMVFNHFMHMPVSYFDKEKTGNLLSRITYDSEQVSAATSQALVSIVREGAS 152 Query: 212 TAIGLGFMFSTSWKLTLLALVIVPVISVAVRKFGRFLRELSHQTQXXXXXXXXXXXXXFG 391 L MF SW+L+L+ + PV++ + + R++S Q Sbjct: 153 IIGLLVLMFYNSWQLSLVLFAVAPVVAWGIGVVSKRFRKISKNMQTMMGNVTASAEQMLK 212 Query: 392 AIRTVRAFAQEPHEISRYGGKVNETLKLGLK 484 + V ++ + E R+ N+ + +K Sbjct: 213 GHKVVLSYGGQDIERQRFDKVSNQMRQQSMK 243
>MSBA_XANCP (Q8P8W4) Lipid A export ATP-binding/permease protein msbA| Length = 589 Score = 60.1 bits (144), Expect = 4e-09 Identities = 40/159 (25%), Positives = 67/159 (42%), Gaps = 1/159 (0%) Frame = +2 Query: 32 SERVVAR-LRQDLFSHLINQEIAFFDVTRTGELLSRLSEDTQIIKNAATTNLSEALRNLT 208 S R +AR LR + S + + FD +L RL D+ + AA + ++ Sbjct: 96 SARSIARDLRVKVMSKYLRLPGSRFDSEPVPSMLIRLGSDSDQVAQAAVDAVKVMIQQSL 155 Query: 209 TTAIGLGFMFSTSWKLTLLALVIVPVISVAVRKFGRFLRELSHQTQXXXXXXXXXXXXXF 388 L M SW++TL LV+ PV++ + K R R +SH Q Sbjct: 156 QVIGALALMLWHSWQVTLTILVLAPVLAWVMDKVARRYRRISHSIQESGAHLLQAADQTL 215 Query: 389 GAIRTVRAFAQEPHEISRYGGKVNETLKLGLKQAKVVGL 505 + + V+ + + E+ RY G + L+L +K G+ Sbjct: 216 SSHQEVKIYGAQQSEMERYSGLADRNLRLAMKVESTRGI 254
>MSBA_XANAC (Q8PKS5) Lipid A export ATP-binding/permease protein msbA| Length = 589 Score = 60.1 bits (144), Expect = 4e-09 Identities = 40/159 (25%), Positives = 67/159 (42%), Gaps = 1/159 (0%) Frame = +2 Query: 32 SERVVAR-LRQDLFSHLINQEIAFFDVTRTGELLSRLSEDTQIIKNAATTNLSEALRNLT 208 S R +AR LR + + + + FD +L RL D+ + AA + ++ Sbjct: 96 SARSIARDLRIKVMAKYLRLPGSRFDSEPVPSMLIRLGSDSDQVAQAAVDAVKVMIQQSL 155 Query: 209 TTAIGLGFMFSTSWKLTLLALVIVPVISVAVRKFGRFLRELSHQTQXXXXXXXXXXXXXF 388 L M SW++TL LV+ PV++ + K R R +SH Q Sbjct: 156 QVIGALALMLWHSWQVTLTILVLAPVLAWVMDKVARRYRRISHSIQESGAQLLQAADQTL 215 Query: 389 GAIRTVRAFAQEPHEISRYGGKVNETLKLGLKQAKVVGL 505 + + V+ + + E+ RYG N L+L +K G+ Sbjct: 216 SSHQEVKIYGAQQTEMERYGALANRNLRLAMKVESTRGI 254
>MDLB_BUCBP (Q89A96) Multidrug resistance-like ATP-binding protein mdlB (EC| 3.6.3.44) Length = 578 Score = 59.7 bits (143), Expect = 5e-09 Identities = 33/136 (24%), Positives = 60/136 (44%) Frame = +2 Query: 17 LFNSASERVVARLRQDLFSHLINQEIAFFDVTRTGELLSRLSEDTQIIKNAATTNLSEAL 196 +FN S V+ +LR D+ S + I FD G+ +SR++ DT+ IK T + Sbjct: 86 IFNKISLTVIQKLRYDVMSSTLQLPIKMFDQRPIGQFISRITNDTETIKELYDTVIKSLF 145 Query: 197 RNLTTTAIGLGFMFSTSWKLTLLALVIVPVISVAVRKFGRFLRELSHQTQXXXXXXXXXX 376 +N+ I L MF W++ +A +I P+ + + + F + + + + Sbjct: 146 QNIILILITLITMFILEWRMACIASIIFPIALIIMLLYQYFSKPILRKIKVYIANIYNIF 205 Query: 377 XXXFGAIRTVRAFAQE 424 I ++ F QE Sbjct: 206 NEIINGIDVIQQFHQE 221
>MDR9_ARATH (Q9M0M2) Multidrug resistance protein 9 (P-glycoprotein 9)| Length = 1323 Score = 58.5 bits (140), Expect = 1e-08 Identities = 47/168 (27%), Positives = 77/168 (45%), Gaps = 4/168 (2%) Frame = +2 Query: 35 ERVVARLRQDLFSHLINQEIAFFDV-TRTGELLSRLSEDTQIIKNAATTNLSEALRNLTT 211 ER A +R ++ Q+I +FD T TGE++ R+S DT +I++A + + + L T Sbjct: 103 ERQSATIRGLYLKTILRQDIGYFDTETNTGEVIGRMSGDTILIQDAMGEKVGKFTQLLCT 162 Query: 212 TAIGLGFMFSTSWKLTLLALVI---VPVISVAVRKFGRFLRELSHQTQXXXXXXXXXXXX 382 G F +K LLA V+ +P+I +A + +++ + Q Sbjct: 163 FLGGFAIAF---YKGPLLAGVLCSCIPLIVIAGAAMSLIMSKMAGRGQVAYAEAGNVVEQ 219 Query: 383 XFGAIRTVRAFAQEPHEISRYGGKVNETLKLGLKQAKVVGLFSGGLNA 526 GAIRTV AF E +Y K+ K ++Q + G G + A Sbjct: 220 TVGAIRTVVAFTGEKQATEKYESKLEIAYKTVVQQGLISGFGLGTMLA 267 Score = 52.0 bits (123), Expect = 1e-06 Identities = 43/196 (21%), Positives = 74/196 (37%), Gaps = 29/196 (14%) Frame = +2 Query: 14 WLFNSASERVVARLRQDLFSHLINQEIAFFDVTRTGE----------------------- 124 + F A +++ R+R F +++QEI++FD T Sbjct: 748 YFFGIAGGKLIKRIRSMCFDKVVHQEISWFDDTANSRYYNFIYIINRRILYVLILIFICV 807 Query: 125 ------LLSRLSEDTQIIKNAATTNLSEALRNLTTTAIGLGFMFSTSWKLTLLALVIVPV 286 L S D +++ L+ ++N+ T GL F+ +W L L+ L + P Sbjct: 808 LLPPVRLERECSTDASTVRSLVGDALALIVQNIATVTTGLIIAFTANWILALIVLALSPF 867 Query: 287 ISVAVRKFGRFLRELSHQTQXXXXXXXXXXXXXFGAIRTVRAFAQEPHEISRYGGKVNET 466 I + +FL S + +IRTV +F E + Y K + Sbjct: 868 IVIQGYAQTKFLTGFSADAKAMYEEASQVANDAVSSIRTVASFCAEEKVMDLYQQKCDGP 927 Query: 467 LKLGLKQAKVVGLFSG 514 K G++ +GL SG Sbjct: 928 KKNGVR----LGLLSG 939
>PMD1_SCHPO (P36619) Leptomycin B resistance protein pmd1| Length = 1362 Score = 58.2 bits (139), Expect = 1e-08 Identities = 39/165 (23%), Positives = 65/165 (39%) Frame = +2 Query: 20 FNSASERVVARLRQDLFSHLINQEIAFFDVTRTGELLSRLSEDTQIIKNAATTNLSEALR 199 F A ER+ R+RQD +++Q I +FD GE+ +R++ DT I++ + Sbjct: 164 FIIAGERIARRIRQDYLHAILSQNIGYFDRLGAGEITTRITTDTNFIQDGLGEKVGLVFF 223 Query: 200 NLTTTAIGLGFMFSTSWKLTLLALVIVPVISVAVRKFGRFLRELSHQTQXXXXXXXXXXX 379 + T G F WK TL+ + P I + F+ + + Sbjct: 224 AIATFVSGFVIAFIRHWKFTLILSSMFPAICGGIGLGVPFITKNTKGQIAVVAESSTFVE 283 Query: 380 XXFGAIRTVRAFAQEPHEISRYGGKVNETLKLGLKQAKVVGLFSG 514 F IR AF + Y + + G+ +A +GL G Sbjct: 284 EVFSNIRNAFAFGTQDILAKLYNKYLITAQRFGINKAIAMGLMVG 328 Score = 50.8 bits (120), Expect = 2e-06 Identities = 44/173 (25%), Positives = 73/173 (42%), Gaps = 2/173 (1%) Frame = +2 Query: 2 ALRAWLFNSASERVVARLRQDLFSHLINQEIAFFDVTRT--GELLSRLSEDTQIIKNAAT 175 A+ + A E V+ R+R LF L+ Q++ FFD + G + + LS Q ++ + Sbjct: 854 AISNFAMTYAMEAVLQRIRYHLFRTLLRQDVEFFDRSENTVGAITTSLSTKIQSLEGLSG 913 Query: 176 TNLSEALRNLTTTAIGLGFMFSTSWKLTLLALVIVPVISVAVRKFGRFLRELSHQTQXXX 355 L + LT +T WKL L+ L PVI A R L ++ + Sbjct: 914 PTLGTFFQILTNIISVTILSLATGWKLGLVTLSTSPVIITAGYYRVRALDQVQEKLSAAY 973 Query: 356 XXXXXXXXXXFGAIRTVRAFAQEPHEISRYGGKVNETLKLGLKQAKVVGLFSG 514 AIRTV + +E + + Y + +K G +++ + L SG Sbjct: 974 KESAAFACESTSAIRTVASLNREENVFAEY---CDSLIKPG-RESAIASLKSG 1022
>YWJA_BACSU (P45861) Hypothetical ABC transporter ATP-binding protein ywjA| Length = 575 Score = 57.4 bits (137), Expect = 3e-08 Identities = 34/131 (25%), Positives = 54/131 (41%) Frame = +2 Query: 53 LRQDLFSHLINQEIAFFDVTRTGELLSRLSEDTQIIKNAATTNLSEALRNLTTTAIGLGF 232 +R+ LF HL F+D +TG L+S+L+ D I A + + T G Sbjct: 89 MRKSLFDHLQKLSFKFYDNNKTGTLMSKLTNDLMYIGEVAHHGPEDLFIAVMTILGAFGV 148 Query: 233 MFSTSWKLTLLALVIVPVISVAVRKFGRFLRELSHQTQXXXXXXXXXXXXXFGAIRTVRA 412 M +W+L LL +I+P++ F + + + G IR V+A Sbjct: 149 MLFINWQLALLTFIIMPIVIWLALYFNKKMTKAFTTLNKDIGDFSARVENNIGGIRLVQA 208 Query: 413 FAQEPHEISRY 445 F E E R+ Sbjct: 209 FGNEAFEKERF 219
>MDR10_ARATH (Q9SGY1) Multidrug resistance protein 10 (P-glycoprotein 10)| Length = 1316 Score = 56.2 bits (134), Expect = 6e-08 Identities = 46/183 (25%), Positives = 72/183 (39%), Gaps = 18/183 (9%) Frame = +2 Query: 20 FNSASERVVARLRQDLFSHLINQEIAFFD-VTRTGELL-SRLSEDTQIIKNAATTNLSEA 193 F ER+ R+RQ +FS ++ EI +FD V T +L SRL D +++ + Sbjct: 790 FGIMGERLTLRVRQKMFSAILRNEIGWFDKVDNTSSMLASRLESDATLLRTIVVDRSTIL 849 Query: 194 LRNLTTTAIGLGFMFSTSWKLTLLALVIVPV-----ISVAVRKFGR-----------FLR 325 L NL F +W+LTL+ L P+ IS R F R F++ Sbjct: 850 LENLGLVVTAFIISFILNWRLTLVVLATYPLIISGHISEVKRSFLRFYILFFGRQKIFMQ 909 Query: 326 ELSHQTQXXXXXXXXXXXXXFGAIRTVRAFAQEPHEISRYGGKVNETLKLGLKQAKVVGL 505 IRTV AF E + Y ++ E + ++ ++ G+ Sbjct: 910 GYGGNLSKAYLKANMLAGESISNIRTVVAFCAEEKVLDLYSKELLEPSERSFRRGQMAGI 969 Query: 506 FSG 514 G Sbjct: 970 LYG 972 Score = 54.7 bits (130), Expect = 2e-07 Identities = 43/198 (21%), Positives = 81/198 (40%), Gaps = 29/198 (14%) Frame = +2 Query: 35 ERVVARLRQDLFSHLINQEIAFFDVT-RTGELLSRLSEDTQIIKNAATTNL--------- 184 ER A++R+ +++Q+I+ FD TGE++S ++ + ++++A + + Sbjct: 113 ERQAAKIRKAYLRSMLSQDISLFDTEISTGEVISAITSEILVVQDAISEKVRYTKIKPVL 172 Query: 185 -------------------SEALRNLTTTAIGLGFMFSTSWKLTLLALVIVPVISVAVRK 307 + ++ G F++ W+++L+ L IVP I++A Sbjct: 173 VLNFGCWIFNFPIASMHLVGNFMHFISRFIAGFAIGFASVWQISLVTLSIVPFIALAGGI 232 Query: 308 FGRFLRELSHQTQXXXXXXXXXXXXXFGAIRTVRAFAQEPHEISRYGGKVNETLKLGLKQ 487 + L + + G +RTV+AF E +S Y G + T G K Sbjct: 233 YAFVSSGLIVRVRKSYVKANEIAEEVIGNVRTVQAFTGEEKAVSSYQGALRNTYNYGRKA 292 Query: 488 AKVVGLFSGGLNAASTLS 541 GL G L+ LS Sbjct: 293 GLAKGLGLGSLHFVLFLS 310
>EXP8_STRPN (P35598) Putative ABC transporter ATP-binding protein exp8| (Exported protein 8) Length = 583 Score = 55.5 bits (132), Expect = 1e-07 Identities = 35/136 (25%), Positives = 66/136 (48%) Frame = +2 Query: 17 LFNSASERVVARLRQDLFSHLINQEIAFFDVTRTGELLSRLSEDTQIIKNAATTNLSEAL 196 LF S +V +R+D F+++ +++FD T G ++SRL+ DT+ I + + LS + Sbjct: 85 LFARVSYSIVRDIRRDAFANMEKLGMSYFDKTPAGSIVSRLTNDTETISDMFSGILSSFI 144 Query: 197 RNLTTTAIGLGFMFSTSWKLTLLALVIVPVISVAVRKFGRFLRELSHQTQXXXXXXXXXX 376 + L M ++LT L L+ +P+I + V + + ++ +T+ Sbjct: 145 SAVFIFLTTLYTMLVLDFRLTALVLLFLPLIFLLVNLYRKKSVKIIEKTRSLLSDINSKL 204 Query: 377 XXXFGAIRTVRAFAQE 424 IR ++AF QE Sbjct: 205 AENIEGIRIIQAFNQE 220
>MDLB_BUCAI (P57552) Multidrug resistance-like ATP-binding protein mdlB (EC| 3.6.3.44) Length = 580 Score = 55.1 bits (131), Expect = 1e-07 Identities = 31/136 (22%), Positives = 62/136 (45%) Frame = +2 Query: 17 LFNSASERVVARLRQDLFSHLINQEIAFFDVTRTGELLSRLSEDTQIIKNAATTNLSEAL 196 LFN + + +LRQD+ + Q I+ FD G+++S+++ DT+ +K T Sbjct: 88 LFNKIAVESINKLRQDVMYAALQQPISEFDSQPIGQMISKVTNDTEAVKELYDTVGPTLF 147 Query: 197 RNLTTTAIGLGFMFSTSWKLTLLALVIVPVISVAVRKFGRFLRELSHQTQXXXXXXXXXX 376 R++ I L MF+ W + L+AL I+P++ + + + L + + Sbjct: 148 RSIILIFIILFAMFTLEWHMALVALFILPLVITIMLVYQYYSTPLLRKVRYYLAEINNKF 207 Query: 377 XXXFGAIRTVRAFAQE 424 + ++ F Q+ Sbjct: 208 NETINGMNVIQQFCQQ 223
>LCNC_LACLA (Q00564) Lactococcin-A transport/processing ATP-binding protein| lcnC (EC 3.4.22.-) Length = 715 Score = 53.9 bits (128), Expect = 3e-07 Identities = 36/139 (25%), Positives = 61/139 (43%) Frame = +2 Query: 8 RAWLFNSASERVVARLRQDLFSHLINQEIAFFDVTRTGELLSRLSEDTQIIKNAATTNLS 187 +A+L N S+R+ + H+ ++FF RTGE+ SR S+ + I+ A+T LS Sbjct: 226 KAFLLNVLSQRLAIDVILSYIRHIFQLPMSFFSTRRTGEITSRFSDASSILDAIASTILS 285 Query: 188 EALRNLTTTAIGLGFMFSTSWKLTLLALVIVPVISVAVRKFGRFLRELSHQTQXXXXXXX 367 L GL + + +L LL L+ +P+ V + F + +H+ Sbjct: 286 LFLDLTIVVMTGL-ILGLQNMQLFLLVLLAIPLYIVVIIIFTPLFEKQNHEVMQTNAVLN 344 Query: 368 XXXXXXFGAIRTVRAFAQE 424 I T++A A E Sbjct: 345 SSIIEDINGIETIKALASE 363
>MSBA_BORPE (Q7VWD8) Lipid A export ATP-binding/permease protein msbA| Length = 623 Score = 53.5 bits (127), Expect = 4e-07 Identities = 35/113 (30%), Positives = 56/113 (49%) Frame = +2 Query: 5 LRAWLFNSASERVVARLRQDLFSHLINQEIAFFDVTRTGELLSRLSEDTQIIKNAATTNL 184 L AW+ N+ V+ +R ++F L+ A F TG LL+R + D + AT + Sbjct: 127 LLAWVANN----VLRGIRGEMFERLLGLPDADFKRGDTGRLLNRFTIDAGNVTGYATDVI 182 Query: 185 SEALRNLTTTAIGLGFMFSTSWKLTLLALVIVPVISVAVRKFGRFLRELSHQT 343 + +R +G + SW LTL+ LV++PV R F R LR ++ +T Sbjct: 183 TVLVRETLVVIALIGVLLYMSWALTLIILVMLPVSVGIARAFTRRLRRINRET 235
>MSBA_BORPA (Q7W9N7) Lipid A export ATP-binding/permease protein msbA| Length = 623 Score = 53.5 bits (127), Expect = 4e-07 Identities = 35/113 (30%), Positives = 56/113 (49%) Frame = +2 Query: 5 LRAWLFNSASERVVARLRQDLFSHLINQEIAFFDVTRTGELLSRLSEDTQIIKNAATTNL 184 L AW+ N+ V+ +R ++F L+ A F TG LL+R + D + AT + Sbjct: 127 LLAWVANN----VLRGIRGEMFERLLGLPDADFKRGDTGRLLNRFTIDAGNVTGYATDVI 182 Query: 185 SEALRNLTTTAIGLGFMFSTSWKLTLLALVIVPVISVAVRKFGRFLRELSHQT 343 + +R +G + SW LTL+ LV++PV R F R LR ++ +T Sbjct: 183 TVLVRETLVVIALIGVLLYMSWALTLIILVMLPVSVGIARAFTRRLRRINRET 235
>MSBA_BORBR (Q7WH20) Lipid A export ATP-binding/permease protein msbA| Length = 623 Score = 53.5 bits (127), Expect = 4e-07 Identities = 35/113 (30%), Positives = 56/113 (49%) Frame = +2 Query: 5 LRAWLFNSASERVVARLRQDLFSHLINQEIAFFDVTRTGELLSRLSEDTQIIKNAATTNL 184 L AW+ N+ V+ +R ++F L+ A F TG LL+R + D + AT + Sbjct: 127 LLAWVANN----VLRGIRGEMFERLLGLPDADFKRGDTGRLLNRFTIDAGNVTGYATDVI 182 Query: 185 SEALRNLTTTAIGLGFMFSTSWKLTLLALVIVPVISVAVRKFGRFLRELSHQT 343 + +R +G + SW LTL+ LV++PV R F R LR ++ +T Sbjct: 183 TVLVRETLVVIALIGVLLYMSWALTLIILVMLPVSVGIARAFTRRLRRINRET 235
>Y742_STRCO (Q9ZNB0) Hypothetical ABC transporter ATP-binding protein SCO0742| Length = 584 Score = 53.1 bits (126), Expect = 5e-07 Identities = 44/168 (26%), Positives = 74/168 (44%), Gaps = 4/168 (2%) Frame = +2 Query: 2 ALRAWLFNSASERVVARLRQDLFSHLINQEIAFFDVTRTGELLSRLSEDTQIIKNAATTN 181 AL +++ +E VV R+ L S+L+ IA D T G+L++R++ DT +++ T + Sbjct: 80 ALGSYVLRRTAESVVLGARRTLSSYLLRLRIAAVDRTEPGDLMARITSDTTLLREVTTDS 139 Query: 182 L---SEALRNLTTTAIGLGFMFSTSWKLTL-LALVIVPVISVAVRKFGRFLRELSHQTQX 349 L L T + +G + +TL + L V+ + V + R S Q Q Sbjct: 140 LIGLGTGGLTLVATLVMMGVVDPVLLGVTLAVVLGAGTVLGLIVPRINR----ASRQAQD 195 Query: 350 XXXXXXXXXXXXFGAIRTVRAFAQEPHEISRYGGKVNETLKLGLKQAK 493 GA+RTV+A EP E E+ + ++ AK Sbjct: 196 AVGVMGAALERILGALRTVKASGAEPREERVLHEAAEESWRQSVRAAK 243
>LCNCL_LACLA (Q9CJB8) Lactococcin transport/processing ATP-binding protein| lcnC-like (EC 3.4.22.-) Length = 715 Score = 53.1 bits (126), Expect = 5e-07 Identities = 36/139 (25%), Positives = 60/139 (43%) Frame = +2 Query: 8 RAWLFNSASERVVARLRQDLFSHLINQEIAFFDVTRTGELLSRLSEDTQIIKNAATTNLS 187 +A+L N S+R+ + H+ ++FF RTGE+ SR S+ + I+ A+T LS Sbjct: 226 KAFLLNVLSQRLAIDVILSYIRHIFQLPMSFFSTRRTGEITSRFSDASSILDAIASTILS 285 Query: 188 EALRNLTTTAIGLGFMFSTSWKLTLLALVIVPVISVAVRKFGRFLRELSHQTQXXXXXXX 367 L GL + + +L LL L+ +P+ V + F +H+ Sbjct: 286 LFLDLTIVLMTGL-ILGLQNMQLFLLVLLAIPLYIVVIIIFTPLFERQNHEVMQTNAILN 344 Query: 368 XXXXXXFGAIRTVRAFAQE 424 I T++A A E Sbjct: 345 SSIIEDINGIETIKALASE 363
>Y1303_MYCBO (P63398) Hypothetical ABC transporter ATP-binding protein Mb1303c| Length = 631 Score = 52.4 bits (124), Expect = 8e-07 Identities = 29/103 (28%), Positives = 55/103 (53%) Frame = +2 Query: 8 RAWLFNSASERVVARLRQDLFSHLINQEIAFFDVTRTGELLSRLSEDTQIIKNAATTNLS 187 +A L N ++ + RLR D+ + +++FD + GELLSR++ D ++++ + +S Sbjct: 140 QARLLNLTVQKTMVRLRTDVEDKVHRLPLSYFDGQQRGELLSRVTNDIDNLQSSLSMTIS 199 Query: 188 EALRNLTTTAIGLGFMFSTSWKLTLLALVIVPVISVAVRKFGR 316 + + ++ T L M S S L L+ L+ VP+ + R R Sbjct: 200 QLVTSILTMVAVLAMMVSISGLLALITLLTVPLSLLVTRAITR 242
>Y1272_MYCTU (P63397) Hypothetical ABC transporter ATP-binding protein| Rv1272c/MT1310 Length = 631 Score = 52.4 bits (124), Expect = 8e-07 Identities = 29/103 (28%), Positives = 55/103 (53%) Frame = +2 Query: 8 RAWLFNSASERVVARLRQDLFSHLINQEIAFFDVTRTGELLSRLSEDTQIIKNAATTNLS 187 +A L N ++ + RLR D+ + +++FD + GELLSR++ D ++++ + +S Sbjct: 140 QARLLNLTVQKTMVRLRTDVEDKVHRLPLSYFDGQQRGELLSRVTNDIDNLQSSLSMTIS 199 Query: 188 EALRNLTTTAIGLGFMFSTSWKLTLLALVIVPVISVAVRKFGR 316 + + ++ T L M S S L L+ L+ VP+ + R R Sbjct: 200 QLVTSILTMVAVLAMMVSISGLLALITLLTVPLSLLVTRAITR 242
>CYAB_BORPE (P18770) Cyclolysin secretion/processing ATP-binding protein cyaB| (EC 3.4.22.-) Length = 712 Score = 51.6 bits (122), Expect = 1e-06 Identities = 43/178 (24%), Positives = 74/178 (41%) Frame = +2 Query: 5 LRAWLFNSASERVVARLRQDLFSHLINQEIAFFDVTRTGELLSRLSEDTQIIKNAATTNL 184 +R +LF S ++ L L++HL+ +A+F R G+ ++R+ E + I+ T N Sbjct: 214 IRTYLFAHTSSKLDVELGARLYAHLLRLPLAYFQARRVGDSVARVRE-LEHIRAFLTGNA 272 Query: 185 SEALRNLTTTAIGLGFMFSTSWKLTLLALVIVPVISVAVRKFGRFLRELSHQTQXXXXXX 364 L ++ + + + MF S KLTL+ L +P + LR Sbjct: 273 VTVLLDVVFSVVFIAVMFFYSVKLTLVVLAALPCYFLLSLVLTPVLRRRLDVKFNRGAEN 332 Query: 365 XXXXXXXFGAIRTVRAFAQEPHEISRYGGKVNETLKLGLKQAKVVGLFSGGLNAASTL 538 I TV++ A EP + ++ + GL A V L + G+ S L Sbjct: 333 QAFLVETVSGIDTVKSLAVEPQWQRNWDRQLAGYVAAGLSVANVAMLANTGVTLISRL 390
>HST6_CANAL (P53706) ATP-dependent permease HST6 (STE6 homolog)| Length = 1323 Score = 51.6 bits (122), Expect = 1e-06 Identities = 33/141 (23%), Positives = 63/141 (44%), Gaps = 4/141 (2%) Frame = +2 Query: 5 LRAWLFNSASERVVARLRQDLFSHLINQEIAFFDVTRTG----ELLSRLSEDTQIIKNAA 172 L ++ N E + LRQ F L NQ+++FF T E+ + L DT+ ++N Sbjct: 739 LSEFILNYCGENWIVSLRQLTFFKLNNQDLSFFTGFDTNWSSSEITALLMNDTRDLRNLI 798 Query: 173 TTNLSEALRNLTTTAIGLGFMFSTSWKLTLLALVIVPVISVAVRKFGRFLRELSHQTQXX 352 + ++ T IG+ + + WKL L+ + VP++ + +G+ L + ++ + Sbjct: 799 SQFFPLLANLVSMTLIGIIWSIVSGWKLALVGISFVPLVLLVTVLYGKILESIENKYKCK 858 Query: 353 XXXXXXXXXXXFGAIRTVRAF 415 IRT++ F Sbjct: 859 VNNVELDLYRTITTIRTIKIF 879 Score = 33.1 bits (74), Expect = 0.52 Identities = 25/154 (16%), Positives = 65/154 (42%), Gaps = 3/154 (1%) Frame = +2 Query: 47 ARLRQDLFSHLINQEIAFFDVTRTGELLSRLSEDTQIIKNAATTN---LSEALRNLTTTA 217 +R R +++ +IN+ +++D + L+ +L++ + I+ + N L+ ++ + Sbjct: 124 SRARMQIYNKIINESQSWYDSKQN--LIGQLTQINRCIEELRSCNGEILASLMQTIVLIL 181 Query: 218 IGLGFMFSTSWKLTLLALVIVPVISVAVRKFGRFLRELSHQTQXXXXXXXXXXXXXFGAI 397 L F SW TL+ + P++++ FG+ + + Sbjct: 182 ALLIMSFYQSWSTTLIIMASFPIMALCGWYFGKLTYKAQQDENEVTSKASKVFNWCYVNP 241 Query: 398 RTVRAFAQEPHEISRYGGKVNETLKLGLKQAKVV 499 VR F + E++++ + ++ + K + V Sbjct: 242 EMVRFFNSKNIELTKFKQLIEKSAQFYYKLSHAV 275
>COMA_STRR6 (P59653) Transport/processing ATP-binding protein comA (EC| 3.4.22.-) Length = 717 Score = 49.7 bits (117), Expect = 5e-06 Identities = 32/133 (24%), Positives = 59/133 (44%) Frame = +2 Query: 74 HLINQEIAFFDVTRTGELLSRLSEDTQIIKNAATTNLSEALRNLTTTAIGLGFMFSTSWK 253 H+ + ++FF RTGE++SR ++ II A+T LS L T I L +FS + Sbjct: 248 HVFHLPMSFFATRRTGEIVSRFTDANSIIDALASTILSIFLDVSTVVIISL-VLFSQNTN 306 Query: 254 LTLLALVIVPVISVAVRKFGRFLRELSHQTQXXXXXXXXXXXXXFGAIRTVRAFAQEPHE 433 L + L+ +P+ +V + F + +++ T I T+++ E Sbjct: 307 LFFMTLLALPIYTVIIFAFMKPFEKMNRDTMEANAVLSSSIIEDINGIETIKSLTSESQR 366 Query: 434 ISRYGGKVNETLK 472 + + + LK Sbjct: 367 YQKIDKEFVDYLK 379
>COMA_STRPN (Q03727) Transport/processing ATP-binding protein comA (EC| 3.4.22.-) Length = 717 Score = 49.7 bits (117), Expect = 5e-06 Identities = 32/133 (24%), Positives = 59/133 (44%) Frame = +2 Query: 74 HLINQEIAFFDVTRTGELLSRLSEDTQIIKNAATTNLSEALRNLTTTAIGLGFMFSTSWK 253 H+ + ++FF RTGE++SR ++ II A+T LS L T I L +FS + Sbjct: 248 HVFHLPMSFFATRRTGEIVSRFTDANSIIDALASTILSIFLDVSTVVIISL-VLFSQNTN 306 Query: 254 LTLLALVIVPVISVAVRKFGRFLRELSHQTQXXXXXXXXXXXXXFGAIRTVRAFAQEPHE 433 L + L+ +P+ +V + F + +++ T I T+++ E Sbjct: 307 LFFMTLLALPIYTVIIFAFMKPFEKMNRDTMEANAVLSSSIIEDINGIETIKSLTSESQR 366 Query: 434 ISRYGGKVNETLK 472 + + + LK Sbjct: 367 YQKIDKEFVDYLK 379
>MSBA_XYLFA (Q9PEE7) Lipid A export ATP-binding/permease protein msbA| Length = 589 Score = 49.3 bits (116), Expect = 7e-06 Identities = 30/140 (21%), Positives = 56/140 (40%) Frame = +2 Query: 101 FDVTRTGELLSRLSEDTQIIKNAATTNLSEALRNLTTTAIGLGFMFSTSWKLTLLALVIV 280 FD +L RL D++ + +A + ++ L M SW +TL L++ Sbjct: 120 FDGEPVASMLVRLGSDSEQVAHAVIDAMKVMVQQTLQVIGALVVMLWYSWTVTLAILLVA 179 Query: 281 PVISVAVRKFGRFLRELSHQTQXXXXXXXXXXXXXFGAIRTVRAFAQEPHEISRYGGKVN 460 P+++ +++ + R +SH Q + V+ +A + E+ RY N Sbjct: 180 PLLAWVMQRVAKRYRRISHHIQESNAQLMQAADQALSNYQDVKVYAAQESELERYARLAN 239 Query: 461 ETLKLGLKQAKVVGLFSGGL 520 L L +K L S + Sbjct: 240 INLGLAIKVESTRSLSSAAV 259
>Y4GM_RHISN (P55469) Probable ABC transporter ATP-binding protein y4gM| Length = 586 Score = 49.3 bits (116), Expect = 7e-06 Identities = 38/171 (22%), Positives = 75/171 (43%), Gaps = 7/171 (4%) Frame = +2 Query: 23 NSASERVVARLRQDLFSHLINQEIAFFDVTRTGELLSRLSEDTQIIKNAATTNLSEALRN 202 + A ++A ++ LF H++ Q ++F+ + + ELL RL+ + Q +++ ++ +R+ Sbjct: 92 SKAGNNIIAHTQRRLFEHVLRQGLSFYSIYPSSELLVRLTNNAQAVRSVIELVVTSFIRD 151 Query: 203 LTTTAIGLGFMFSTSWKLTLLALVIVPVISVAVRKFGRFLRELSHQTQXXXXXXXXXXXX 382 L + L M L+L++ + P + VR R +R++ Sbjct: 152 LFSLMGLLAVMVIQQPLLSLVSAAVGPGAILGVRVLTRKVRKIMELEIASIGQIIQSVQE 211 Query: 383 XFGAIRTVRAFAQEP---HEISRYGGKV----NETLKLGLKQAKVVGLFSG 514 IR V+AFA E + +Y G V N +L + ++ SG Sbjct: 212 TSTGIRIVKAFALEDFMRRRMDKYIGDVERRANSIARLEAASSPIMETLSG 262
>MSBA_XYLFT (Q87EF0) Lipid A export ATP-binding/permease protein msbA| Length = 589 Score = 48.5 bits (114), Expect = 1e-05 Identities = 28/128 (21%), Positives = 53/128 (41%) Frame = +2 Query: 101 FDVTRTGELLSRLSEDTQIIKNAATTNLSEALRNLTTTAIGLGFMFSTSWKLTLLALVIV 280 FD +L RL D++ + +A + ++ L M SW +TL L++ Sbjct: 120 FDGEPVASMLVRLGSDSEQVAHAVIDAMKVMVQQTLQVIGALVVMLWYSWTVTLAILLVA 179 Query: 281 PVISVAVRKFGRFLRELSHQTQXXXXXXXXXXXXXFGAIRTVRAFAQEPHEISRYGGKVN 460 P+++ +++ + R +SH Q + V+ +A + E+ RY N Sbjct: 180 PLLAWVMQRVAKRYRRISHHIQESNAQLMQAADQALSNYQDVKVYAAQESELERYARLAN 239 Query: 461 ETLKLGLK 484 L L +K Sbjct: 240 INLGLAVK 247
>MRP11_ARATH (Q9SKX0) Multidrug resistance-associated protein 11 (EC 3.6.3.44)| (Glutathione S-conjugate transporting ATPase 11) (ATP-energized glutathione S-conjugate pump 11) Length = 1194 Score = 46.6 bits (109), Expect = 5e-05 Identities = 40/153 (26%), Positives = 61/153 (39%), Gaps = 6/153 (3%) Frame = +2 Query: 5 LRAWLFNSASERVVARLRQDLFSHLINQEIAFFDVTRTGELLSRLSEDTQIIKNAATTNL 184 +RA+ F + + L S LIN FFD T +G +L+R S D I ++ L Sbjct: 693 VRAFSFAFGGLKAAVHVHNALISKLINAPTQFFDQTPSGRILNRFSSDLYTIDDSLPFIL 752 Query: 185 SEALRNLTTTAIGLGFMFSTSWKLTLLALVIVPV------ISVAVRKFGRFLRELSHQTQ 346 + L N LG + S+ L L+++P + V R R LR L ++ Sbjct: 753 NILLANFVGL---LGIIVVLSYVQVLFLLLLLPFWYIYSKLQVFYRSTSRELRRLDSVSR 809 Query: 347 XXXXXXXXXXXXXFGAIRTVRAFAQEPHEISRY 445 T+RAF E H + R+ Sbjct: 810 ---SPIYASFTETLDGSSTIRAFKSEEHFVGRF 839
>MRP5_RAT (Q9QYM0) Multidrug resistance-associated protein 5| Length = 1436 Score = 45.4 bits (106), Expect = 1e-04 Identities = 34/151 (22%), Positives = 63/151 (41%), Gaps = 3/151 (1%) Frame = +2 Query: 2 ALRAWLFNSASERVVARLRQDLFSHLINQEIAFFDVTRTGELLSRLSEDTQIIKNAATTN 181 A+R +F + R +RL +LF ++ + FFD T TG +L+R S+D + Sbjct: 929 AIRGVVFVKGTLRASSRLHDELFRRILRSPMKFFDTTPTGRILNRFSKDMDEVDVRLPFQ 988 Query: 182 LSEALRNLTTTAIGLGFMFST-SWKLTLLA--LVIVPVISVAVRKFGRFLRELSHQTQXX 352 ++N+ +G + W L + L++ V+ + R R L+ L + TQ Sbjct: 989 AEMFIQNVILVFFCVGMIAGVFPWFLVAVGPLLILFSVLHIVSRVLIRELKRLDNITQ-- 1046 Query: 353 XXXXXXXXXXXFGAIRTVRAFAQEPHEISRY 445 + T+ A+ + + RY Sbjct: 1047 -SPFLSHITSSIQGLATIHAYNKRQEFLHRY 1076
>PEDD_PEDAC (P36497) Pediocin PA-1 transport/processing ATP-binding protein| pedD (EC 3.4.22.-) (Pediocin AcH transport ATP-binding protein papD) Length = 724 Score = 45.1 bits (105), Expect = 1e-04 Identities = 31/117 (26%), Positives = 50/117 (42%) Frame = +2 Query: 74 HLINQEIAFFDVTRTGELLSRLSEDTQIIKNAATTNLSEALRNLTTTAIGLGFMFSTSWK 253 HL + + FF GE+ SR S+ ++II +T L+ L A+GL F+ + Sbjct: 250 HLFDLPMNFFTTRHVGEMTSRFSDASKIIDALGSTTLTLFLDMWILLAVGL-FLAYQNIN 308 Query: 254 LTLLALVIVPVISVAVRKFGRFLRELSHQTQXXXXXXXXXXXXXFGAIRTVRAFAQE 424 L L +LV+VP+ V F + L+ T I T+++ E Sbjct: 309 LFLCSLVVVPIYISIVWLFKKTFNRLNQDTMESNAVLNSAIIESLSGIETIKSLTGE 365
>MRP3_ARATH (Q9LK64) Multidrug resistance-associated protein 3 (EC 3.6.3.44)| (Glutathione S-conjugate transporting ATPase 3) (ATP-energized glutathione S-conjugate pump 3) Length = 1514 Score = 45.1 bits (105), Expect = 1e-04 Identities = 39/147 (26%), Positives = 62/147 (42%), Gaps = 7/147 (4%) Frame = +2 Query: 5 LRAWLFNSASERVVARLRQDLFSHLINQEIAFFDVTRTGELLSRLSEDTQIIKNAATTNL 184 LRA L +A + L + + ++FFD T +G ++SR S D ++A L Sbjct: 1007 LRATLLVTAGYKTATELFHKMHHCIFRSPMSFFDSTPSGRIMSRASTD----QSAVDLEL 1062 Query: 185 SEALRNLTTTAIGL----GFMFSTSWKLTLLALVIVPVISVAV---RKFGRFLRELSHQT 343 ++ T I L G M SW L+ LV +PV++ ++ R + RELS Sbjct: 1063 PYQFGSVAITVIQLIGIIGVMSQVSW---LVFLVFIPVVAASIWYQRYYIAAARELSRLV 1119 Query: 344 QXXXXXXXXXXXXXFGAIRTVRAFAQE 424 T+R+F+QE Sbjct: 1120 GVCKAPLIQHFSETISGATTIRSFSQE 1146
>MRP7_ARATH (Q9LK62) Multidrug resistance-associated protein 7 (EC 3.6.3.44)| (Glutathione S-conjugate transporting ATPase 7) (ATP-energized glutathione S-conjugate pump 7) Length = 1493 Score = 44.7 bits (104), Expect = 2e-04 Identities = 31/145 (21%), Positives = 59/145 (40%), Gaps = 4/145 (2%) Frame = +2 Query: 5 LRAWLFNSASERVVARLRQDLFSHLINQEIAFFDVTRTGELLSRLSEDTQIIKNAATTNL 184 +RA L ++ L + + ++FFD T G +L+R S D ++A L Sbjct: 979 VRAMLSAMTGFKIATELFNQMHFRIFRASMSFFDATPIGRILNRASTD----QSAVDLRL 1034 Query: 185 SEALRNLTTTAIGL----GFMFSTSWKLTLLALVIVPVISVAVRKFGRFLRELSHQTQXX 352 NL A+ + G M +W++ ++ + ++ + + + REL+ + Sbjct: 1035 PSQFSNLAIAAVNILGIIGVMGQVAWQVLIVFIPVIAACTWYRQYYISAARELARLSGIS 1094 Query: 353 XXXXXXXXXXXFGAIRTVRAFAQEP 427 I T+R+F QEP Sbjct: 1095 RSPLVQHFSETLSGITTIRSFDQEP 1119
>LAGD_LACLA (P59852) Lactococcin-G-processing and transport ATP-binding protein| lagD (EC 3.4.22.-) Length = 703 Score = 44.3 bits (103), Expect = 2e-04 Identities = 34/159 (21%), Positives = 64/159 (40%) Frame = +2 Query: 8 RAWLFNSASERVVARLRQDLFSHLINQEIAFFDVTRTGELLSRLSEDTQIIKNAATTNLS 187 R++L +R+ + F H+++ ++FF ++GE++SR + +II A+ LS Sbjct: 211 RSYLLLLIGQRMSMSIMLGYFKHVLSLPLSFFATRKSGEIISRFLDANKIIDALASATLS 270 Query: 188 EALRNLTTTAIGLGFMFSTSWKLTLLALVIVPVISVAVRKFGRFLRELSHQTQXXXXXXX 367 L +G S +L LL L +P + V F R + + + Sbjct: 271 LILDIGMVILVGTTLAIQ-STQLFLLTLAFLPFYILVVYVFIRSYDKANTEEMSAGAEVN 329 Query: 368 XXXXXXFGAIRTVRAFAQEPHEISRYGGKVNETLKLGLK 484 I T++++ E H R + +K K Sbjct: 330 SSIIESLKGIETIKSYNGENHVYDRVDSEFVTLMKKSFK 368
>MRP5_MOUSE (Q9R1X5) Multidrug resistance-associated protein 5 (ABC transporter| MOAT-C) (SMRP) Length = 1436 Score = 44.3 bits (103), Expect = 2e-04 Identities = 33/151 (21%), Positives = 63/151 (41%), Gaps = 3/151 (1%) Frame = +2 Query: 2 ALRAWLFNSASERVVARLRQDLFSHLINQEIAFFDVTRTGELLSRLSEDTQIIKNAATTN 181 A+R +F + R +RL +LF ++ + FFD T TG +L+R S+D + Sbjct: 929 AIRGVVFVKGTLRASSRLHDELFRRILRSPMKFFDTTPTGRILNRFSKDMDEVDVRLPFQ 988 Query: 182 LSEALRNLTTTAIGLGFMFST-SWKLTLLA--LVIVPVISVAVRKFGRFLRELSHQTQXX 352 ++N+ +G + W L + L++ ++ + R R L+ L + TQ Sbjct: 989 AEMFIQNVILVFFCVGMIAGVFPWFLVAVGPLLILFSLLHIVSRVLIRELKRLDNITQ-- 1046 Query: 353 XXXXXXXXXXXFGAIRTVRAFAQEPHEISRY 445 + T+ A+ + + RY Sbjct: 1047 -SPFLSHITSSIQGLATIHAYNKRQEFLHRY 1076
>MESD_LEUME (Q10418) Mesentericin Y105 transport/processing ATP-binding protein| mesD (EC 3.4.22.-) Length = 722 Score = 44.3 bits (103), Expect = 2e-04 Identities = 31/139 (22%), Positives = 59/139 (42%) Frame = +2 Query: 8 RAWLFNSASERVVARLRQDLFSHLINQEIAFFDVTRTGELLSRLSEDTQIIKNAATTNLS 187 R +L +R+ + H+ ++FF RTGE++SR ++ II+ A+T LS Sbjct: 231 RDYLLIVMGQRLSIDIILSYIKHIFELPMSFFATRRTGEIVSRFTDANAIIEALASTMLS 290 Query: 188 EALRNLTTTAIGLGFMFSTSWKLTLLALVIVPVISVAVRKFGRFLRELSHQTQXXXXXXX 367 L +G + S L L++L+ +P ++ V F R ++++ Sbjct: 291 VFLDLGILVIVGTVLVVQNS-TLFLISLIAIPAYALVVWLFMRPFSKMNNDQMQAGSMLS 349 Query: 368 XXXXXXFGAIRTVRAFAQE 424 + T++A E Sbjct: 350 SSIIEDINGVETIKALNSE 368
>MRP5_HUMAN (O15440) Multidrug resistance-associated protein 5 (Multi-specific| organic anion transporter-C) (MOAT-C) (pABC11) (SMRP) Length = 1437 Score = 43.5 bits (101), Expect = 4e-04 Identities = 29/118 (24%), Positives = 54/118 (45%), Gaps = 3/118 (2%) Frame = +2 Query: 2 ALRAWLFNSASERVVARLRQDLFSHLINQEIAFFDVTRTGELLSRLSEDTQIIKNAATTN 181 A+R +F + R +RL +LF ++ + FFD T TG +L+R S+D + Sbjct: 930 AIRGVVFVKGTLRASSRLHDELFRRILRSPMKFFDTTPTGRILNRFSKDMDEVDVRLPFQ 989 Query: 182 LSEALRNLTTTAIGLGFMFST-SWKLTLLA--LVIVPVISVAVRKFGRFLRELSHQTQ 346 ++N+ +G + W L + +++ V+ + R R L+ L + TQ Sbjct: 990 AEMFIQNVILVFFCVGMIAGVFPWFLVAVGPLVILFSVLHIVSRVLIRELKRLDNITQ 1047
>STE6_YEAST (P12866) Mating factor A secretion protein STE6 (Multiple drug| resistance protein homolog) (P-glycoprotein) Length = 1290 Score = 40.0 bits (92), Expect = 0.004 Identities = 28/143 (19%), Positives = 63/143 (44%), Gaps = 2/143 (1%) Frame = +2 Query: 8 RAWLFNSASERVVARLRQDLFSHLINQEIAFF--DVTRTGELLSRLSEDTQIIKNAATTN 181 + +L + SE V LR ++ L + + +F + + E+ + + D + +++ + Sbjct: 780 KGFLLDCCSEYWVMDLRNEVMEKLTRKNMDWFSGENNKASEISALVLNDLRDLRSLVSEF 839 Query: 182 LSEALRNLTTTAIGLGFMFSTSWKLTLLALVIVPVISVAVRKFGRFLRELSHQTQXXXXX 361 LS +T + IGL + + WKL+L+ + + P+I + +G L++ + Sbjct: 840 LSAMTSFVTVSTIGLIWALVSGWKLSLVCISMFPLIIIFSAIYGGILQKCETDYKTSVAQ 899 Query: 362 XXXXXXXXFGAIRTVRAFAQEPH 430 I+T++ E H Sbjct: 900 LENCLYQIVTNIKTIKCLQAEFH 922 Score = 34.7 bits (78), Expect = 0.18 Identities = 32/152 (21%), Positives = 63/152 (41%), Gaps = 4/152 (2%) Frame = +2 Query: 2 ALRAWLFNSASERVVARLR-QDLFSHLINQEIAFFDVTRTGELLSRLSEDTQIIKNAATT 178 +L +W+ ER R+R Q L ++L + + ++D +LL ++ + ++ ++ Sbjct: 92 SLTSWMH--IGERQGFRIRSQILEAYLEEKPMEWYD--NNEKLLGDFTQINRCVEELRSS 147 Query: 179 NLSEA---LRNLTTTAIGLGFMFSTSWKLTLLALVIVPVISVAVRKFGRFLRELSHQTQX 349 + + +NL LG F SW LTL+ L P+I+ F R + S + Sbjct: 148 SAEASAITFQNLVAICALLGTSFYYSWSLTLIILCSSPIITFFAVVFSRMIHVYSEKENS 207 Query: 350 XXXXXXXXXXXXFGAIRTVRAFAQEPHEISRY 445 A + VR + + E ++ Sbjct: 208 ETSKAAQLLTWSMNAAQLVRLYCTQRLERKKF 239
>MRP14_ARATH (Q9LYS2) Multidrug resistance-associated protein 14 (EC 3.6.3.44)| (Glutathione S-conjugate transporting ATPase 14) (ATP-energized glutathione S-conjugate pump 14) Length = 1389 Score = 40.0 bits (92), Expect = 0.004 Identities = 28/124 (22%), Positives = 52/124 (41%), Gaps = 4/124 (3%) Frame = +2 Query: 65 LFSHLINQ----EIAFFDVTRTGELLSRLSEDTQIIKNAATTNLSEALRNLTTTAIGLGF 232 LFS L+N ++F+D T G +LSR+S D I+ L + + T LG Sbjct: 897 LFSQLLNSLFRAPMSFYDSTPLGRILSRVSSDLSIVDLDVPFGLIFVVASSVNTGCSLGV 956 Query: 233 MFSTSWKLTLLALVIVPVISVAVRKFGRFLRELSHQTQXXXXXXXXXXXXXFGAIRTVRA 412 + +W++ +++ +V + + + + +EL T+RA Sbjct: 957 LAIVTWQVLFVSVPMVYLAFRLQKYYFQTAKELMRINGTTRSYVANHLAESVAGAITIRA 1016 Query: 413 FAQE 424 F +E Sbjct: 1017 FDEE 1020
>MRP8_ARATH (Q8VZZ4) Multidrug resistance-associated protein 8 (EC 3.6.3.44)| (Glutathione S-conjugate transporting ATPase 8) (ATP-energized glutathione S-conjugate pump 8) Length = 1466 Score = 38.5 bits (88), Expect = 0.012 Identities = 30/145 (20%), Positives = 56/145 (38%), Gaps = 4/145 (2%) Frame = +2 Query: 5 LRAWLFNSASERVVARLRQDLFSHLINQEIAFFDVTRTGELLSRLSEDTQIIKNAATTNL 184 +RA L ++ L + + ++FFD T G +L+R S D + A L Sbjct: 957 IRALLVAMTGFKMATELFTQMHLRIFRASMSFFDATPMGRILNRASTDQSV----ADLRL 1012 Query: 185 SEALRNLTTTAIGL----GFMFSTSWKLTLLALVIVPVISVAVRKFGRFLRELSHQTQXX 352 + AI + G + +W++ ++ + +V + + + REL+ Sbjct: 1013 PGQFAYVAIAAINILGIIGVIVQVAWQVLIVFIPVVAACAWYRQYYISAARELARLAGIS 1072 Query: 353 XXXXXXXXXXXFGAIRTVRAFAQEP 427 I T+R+F QEP Sbjct: 1073 RSPVVHHFSETLSGITTIRSFDQEP 1097
>ABCB7_RAT (Q704E8) ATP-binding cassette sub-family B member 7, mitochondrial| precursor (ATP-binding cassette transporter 7) (ABC transporter 7 protein) Length = 752 Score = 38.1 bits (87), Expect = 0.016 Identities = 37/178 (20%), Positives = 71/178 (39%), Gaps = 4/178 (2%) Frame = +2 Query: 5 LRAWLFNSASERVVARLRQDLFSHLINQEIAFFDVTRTGELLSRLSEDTQ---IIKNAAT 175 +R +F ++ + R+ +++F HL N ++ F +TG L + T+ + +A Sbjct: 209 VRNAVFGKVAQNSIRRIAKNVFLHLHNLDLGFHLSRQTGALSKAIDRGTRGISFVLSALV 268 Query: 176 TNLSEALRNLTTTAIGLGFMFSTSWKL-TLLALVIVPVISVAVRKFGRFLRELSHQTQXX 352 NL + +T + L + + L TL L +VAV ++ R ++ Sbjct: 269 FNLLPIVFEMTLVSSVLYYKCGAQFALVTLGTLGAYTAFTVAVTRWRTRFRIEMNKADND 328 Query: 353 XXXXXXXXXXXFGAIRTVRAFAQEPHEISRYGGKVNETLKLGLKQAKVVGLFSGGLNA 526 + TV+ F E +E RY G + LK + + + G +A Sbjct: 329 AGNAAIDSLLNY---ETVKYFNNEKYEAQRYDGFLKTYETASLKSTSTLAMLNFGQSA 383
>MAM1_SCHPO (P78966) Mating factor M secretion protein mam1 (Multiple drug| resistance protein homolog) (P-glycoprotein) Length = 1336 Score = 37.7 bits (86), Expect = 0.021 Identities = 36/166 (21%), Positives = 61/166 (36%), Gaps = 1/166 (0%) Frame = +2 Query: 50 RLRQDLFSHLINQEIAFFDVTRTGE-LLSRLSEDTQIIKNAATTNLSEALRNLTTTAIGL 226 R R F L ++ F+ +T + L++ + Q + + + + NL + L Sbjct: 184 RARSLCFHVLSSKSSTFYSLTESKSGLVNSVDRCIQFYEKSISLPMFHIAENLAISLSCL 243 Query: 227 GFMFSTSWKLTLLALVIVPVISVAVRKFGRFLRELSHQTQXXXXXXXXXXXXXFGAIRTV 406 F SW LTL+ L P+I + V FL + + AI+TV Sbjct: 244 IISFRYSWSLTLVVLASYPIIILVVGFINSFLSSAYEKDRKSSEKAASILEKSISAIQTV 303 Query: 407 RAFAQEPHEISRYGGKVNETLKLGLKQAKVVGLFSGGLNAASTLSV 544 + + E RY T + + F GG++ SV Sbjct: 304 IFHSMQDTEY-RYFADACSTSSKSFLRFSFLDAFQGGVSQFFLYSV 348 Score = 35.4 bits (80), Expect = 0.10 Identities = 21/80 (26%), Positives = 40/80 (50%), Gaps = 2/80 (2%) Frame = +2 Query: 77 LINQEIAFFDVTRTGEL-LSR-LSEDTQIIKNAATTNLSEALRNLTTTAIGLGFMFSTSW 250 L Q+ A+FD L LS+ L + ++N ++ + E T IG+ + F+T W Sbjct: 862 LFTQDQAWFDQIENYPLVLSKILVNNISDMRNMISSLIEEVFIAFTMAIIGIAWSFATGW 921 Query: 251 KLTLLALVIVPVISVAVRKF 310 +L + + + P++ + R F Sbjct: 922 RLAAVLVAVSPILCLTSRMF 941
>ABCB7_MOUSE (Q61102) ATP-binding cassette sub-family B member 7, mitochondrial| (ATP-binding cassette transporter 7) (ABC transporter 7 protein) (Fragment) Length = 694 Score = 37.7 bits (86), Expect = 0.021 Identities = 37/178 (20%), Positives = 70/178 (39%), Gaps = 4/178 (2%) Frame = +2 Query: 5 LRAWLFNSASERVVARLRQDLFSHLINQEIAFFDVTRTGELLSRLSEDTQ---IIKNAAT 175 +R +F ++ + R+ +++F HL N ++ F +TG L + T+ + +A Sbjct: 151 VRNAVFGKVAQNSIRRIAKNVFLHLHNLDLGFHLSRQTGALSKAIDRGTRGISFVLSALV 210 Query: 176 TNLSEALRNLTTTAIGLGFMFSTSWKL-TLLALVIVPVISVAVRKFGRFLRELSHQTQXX 352 NL + + + L + + L TL L +VAV ++ R ++ Sbjct: 211 FNLLPIVFEMMLVSSVLYYKCGAQFALVTLGTLGAYTAFTVAVTRWRTRFRIEMNKADND 270 Query: 353 XXXXXXXXXXXFGAIRTVRAFAQEPHEISRYGGKVNETLKLGLKQAKVVGLFSGGLNA 526 + TV+ F E +E RY G + LK + + + G NA Sbjct: 271 AGNAAIDSLLNY---ETVKYFNNEKYEAQRYDGFLKTYETASLKSTSTLAMLNFGQNA 325
>Y015_MYCGE (P47261) Hypothetical ABC transporter ATP-binding protein MG015| Length = 589 Score = 36.2 bits (82), Expect = 0.061 Identities = 26/101 (25%), Positives = 52/101 (51%), Gaps = 3/101 (2%) Frame = +2 Query: 35 ERVVARLRQDLFSHLINQEIAFFDVTRTGELLSRLSEDTQIIKNAATTNLSEALR---NL 205 ++ A LR + + + +FFD G+L+SRL+ D I N T +A++ N+ Sbjct: 96 QQTCATLRWKAYLKMQSMSTSFFDTQNNGDLMSRLTNDMYNIDNLFTQAGGQAIQSLFNI 155 Query: 206 TTTAIGLGFMFSTSWKLTLLALVIVPVISVAVRKFGRFLRE 328 TT++ L F+ S ++AL+ + +++ + FL++ Sbjct: 156 LTTSV-LIFLLS-----PVIALISLSILATLITFSFAFLKK 190
>ABCB7_HUMAN (O75027) ATP-binding cassette sub-family B member 7, mitochondrial| precursor (ATP-binding cassette transporter 7) (ABC transporter 7 protein) Length = 752 Score = 34.7 bits (78), Expect = 0.18 Identities = 36/178 (20%), Positives = 70/178 (39%), Gaps = 4/178 (2%) Frame = +2 Query: 5 LRAWLFNSASERVVARLRQDLFSHLINQEIAFFDVTRTGELLSRLSEDTQ---IIKNAAT 175 +R +F ++ + R+ +++F HL N ++ F +TG L + T+ + +A Sbjct: 209 VRNAVFGKVAQNSIRRIAKNVFLHLHNLDLGFHLSRQTGALSKAIDRGTRGISFVLSALV 268 Query: 176 TNLSEALRNLTTTAIGLGFMFSTSWKL-TLLALVIVPVISVAVRKFGRFLRELSHQTQXX 352 NL + + + L + + L TL L +VAV ++ R ++ Sbjct: 269 FNLLPIMFEVMLVSGVLYYKCGAQFALVTLGTLGTYTAFTVAVTRWRTRFRIEMNKADND 328 Query: 353 XXXXXXXXXXXFGAIRTVRAFAQEPHEISRYGGKVNETLKLGLKQAKVVGLFSGGLNA 526 + TV+ F E +E RY G + LK + + + G +A Sbjct: 329 AGNAAIDSLLNY---ETVKYFNNERYEAQRYDGFLKTYETASLKSTSTLAMLNFGQSA 383
>CYDD_BACSU (P94367) Transport ATP-binding protein cydD| Length = 575 Score = 34.3 bits (77), Expect = 0.23 Identities = 24/97 (24%), Positives = 48/97 (49%), Gaps = 7/97 (7%) Frame = +2 Query: 38 RVVARLRQDLFSHLINQEIAFFDVTRTGELLSRLSEDTQIIKNAATTNLSEALRNLTTTA 217 ++V+ +R L++ L + RTG++L LSED + +++A + A+ L A Sbjct: 87 KIVSDMRVRLYNMLEPGALMLRSRFRTGDMLGILSEDIEHLQDAFLKTIFPAISALLLYA 146 Query: 218 IGLGFMFSTSWKLTLL-------ALVIVPVISVAVRK 307 + + + SW +L +V+ PV+S+ V + Sbjct: 147 VSVIALGFFSWPFAILLALYLFVLVVLFPVVSLLVTR 183
>MCHF_ECOLI (Q9EXN5) Probable microcin H47 secretion/processing ATP-binding| protein mchF (EC 3.4.22.-) Length = 698 Score = 34.3 bits (77), Expect = 0.23 Identities = 41/175 (23%), Positives = 73/175 (41%), Gaps = 2/175 (1%) Frame = +2 Query: 5 LRAWLFNSASERVVARLRQDLFSHLINQEIAFFDVTRTGELLSRL-SEDTQIIKNAATTN 181 LRAW S + + + LF+HL+ +AFF+ + G++ SR S DT ++ TT Sbjct: 233 LRAWSSLVMSTLINIQWQSGLFNHLLRLPLAFFERRKLGDIQSRFGSLDT--LRATFTTC 290 Query: 182 LSEALRNLTTTAIGLGFMFSTSWKLTLLALVIVPV-ISVAVRKFGRFLRELSHQTQXXXX 358 + A+ + M LT + L V + + + +G + R++S +T Sbjct: 291 VVGAIMDSIMVVGVFVMMLLYGGYLTWIVLGFTMVYVLIRLVTYG-YYRQISEETLVRGA 349 Query: 359 XXXXXXXXXFGAIRTVRAFAQEPHEISRYGGKVNETLKLGLKQAKVVGLFSGGLN 523 I TV+ + + + + G+K K+ LF GG+N Sbjct: 350 RASSYFMESLYGIATVKIQGMAGIRGTHWLNLKIDAINSGIKLTKMDLLF-GGIN 403
>YCFI_YEAST (P39109) Metal resistance protein YCF1 (Yeast cadmium factor 1)| Length = 1515 Score = 33.9 bits (76), Expect = 0.30 Identities = 21/116 (18%), Positives = 43/116 (37%) Frame = +2 Query: 77 LINQEIAFFDVTRTGELLSRLSEDTQIIKNAATTNLSEALRNLTTTAIGLGFMFSTSWKL 256 ++ + FF+ T G +L+R S D + S+ N + + +T+W+ Sbjct: 1033 VLRAPMTFFETTPIGRILNRFSNDIYKVDALLGRTFSQFFVNAVKVTFTITVICATTWQF 1092 Query: 257 TLLALVIVPVISVAVRKFGRFLRELSHQTQXXXXXXXXXXXXXFGAIRTVRAFAQE 424 + + + + + R REL G + TVR ++Q+ Sbjct: 1093 IFIIIPLSVFYIYYQQYYLRTSRELRRLDSITRSPIYSHFQETLGGLATVRGYSQQ 1148
>Y019_MYCPN (P75094) Hypothetical ABC transporter ATP-binding protein MG015| homolog (D12_orf634) Length = 634 Score = 33.9 bits (76), Expect = 0.30 Identities = 19/82 (23%), Positives = 38/82 (46%) Frame = +2 Query: 35 ERVVARLRQDLFSHLINQEIAFFDVTRTGELLSRLSEDTQIIKNAATTNLSEALRNLTTT 214 + + A LR + + + +FFD G+L+SRL+ D I N + +++L Sbjct: 141 QEICALLRWKAYLKIQSMSTSFFDTQNNGDLMSRLTNDVYNINNLYAQVGGQTIQSLFIL 200 Query: 215 AIGLGFMFSTSWKLTLLALVIV 280 +F S + L++L ++ Sbjct: 201 MTTATILFVLSPVIALISLTVL 222
>ABCB6_HUMAN (Q9NP58) ATP-binding cassette sub-family B member 6, mitochondrial| precursor (Mitochondrial ABC transporter 3) (Mt-ABC transporter 3) (ABC transporter umat) Length = 842 Score = 33.1 bits (74), Expect = 0.52 Identities = 30/151 (19%), Positives = 59/151 (39%), Gaps = 4/151 (2%) Frame = +2 Query: 5 LRAWLFNSASERVVARLRQDLFSHLINQEIAFFDVTRTGELLSRLSEDTQIIKNAATTNL 184 LR +L+ + R+ +FSHL + + RTGE+L T + + + Sbjct: 329 LRTFLWIRVQQFTSRRVELLIFSHLHELSLRWHLGRRTGEVLRIADRGTSSVTGLLSYLV 388 Query: 185 SEALRNLTTTAIGLGF--MFSTSW--KLTLLALVIVPVISVAVRKFGRFLRELSHQTQXX 352 + L IG+ + MF +W + L + + +++ V ++ R + + Sbjct: 389 FNVIPTLADIIIGIIYFSMFFNAWFGLIVFLCMSLYLTLTIVVTEWRTKFRRAMNTQENA 448 Query: 353 XXXXXXXXXXXFGAIRTVRAFAQEPHEISRY 445 F TV+ + E +E+ RY Sbjct: 449 TRARAVDSLLNF---ETVKYYNAESYEVERY 476
>CCSA_GALSU (P31564) Cytochrome c biogenesis protein ccsA| Length = 306 Score = 32.7 bits (73), Expect = 0.67 Identities = 17/35 (48%), Positives = 20/35 (57%) Frame = +2 Query: 140 SEDTQIIKNAATTNLSEALRNLTTTAIGLGFMFST 244 S DT I+KN NL + NL+ IGLGF F T Sbjct: 189 SNDTLILKNEDKLNLLNTIDNLSYRIIGLGFPFLT 223
>MRP10_ARATH (Q9LZJ5) Multidrug resistance-associated protein 10 (EC 3.6.3.44)| (Glutathione S-conjugate transporting ATPase 10) (ATP-energized glutathione S-conjugate pump 10) Length = 1539 Score = 32.3 bits (72), Expect = 0.88 Identities = 33/160 (20%), Positives = 59/160 (36%), Gaps = 3/160 (1%) Frame = +2 Query: 5 LRAWLFNSASERVVARLRQDLFSHLINQEIAFFDVTRTGELLSRLSEDTQIIKNAATTNL 184 LRA+ + + + + L++ ++FFD T +G +LSR S D + + Sbjct: 1035 LRAFYVTHLGLKTAQIFFKQILNSLVHAPMSFFDTTPSGRILSRASTDQTNVDIFIPFMI 1094 Query: 185 SEALRNLTTTAIGLGFMFSTSWKLTLLALVIVPVISVAVRKFGRFL---RELSHQTQXXX 355 TT L T I+P+ + + G +L REL+ Sbjct: 1095 GLVATMYTTL---LSIFIVTCQYAWPTVFFIIPLGWLNIWYRGYYLASSRELTRLDSITK 1151 Query: 356 XXXXXXXXXXFGAIRTVRAFAQEPHEISRYGGKVNETLKL 475 + T+RAF ++P +VN L++ Sbjct: 1152 APVIHHFSESIAGVMTIRAFKKQPMFRQENVKRVNANLRM 1191
>YD01_SCHPO (O14286) Putative ABC transporter C15A10.01 in chromosome I| Length = 693 Score = 32.3 bits (72), Expect = 0.88 Identities = 28/175 (16%), Positives = 69/175 (39%), Gaps = 4/175 (2%) Frame = +2 Query: 5 LRAWLFNSASERVVARLRQDLFSHLINQEIAFFDVTRTGELLSRLSEDTQ---IIKNAAT 175 LR +F S+ + + +++ HL+N ++ F +TG + + T+ I ++ Sbjct: 182 LRNSVFAIVSQSAIRSVSSNVYQHLLNLDMNFHLSKQTGSITRAMDRGTKGISFILSSMV 241 Query: 176 TNLSEALRNLTTTAIGLGFMFSTSWK-LTLLALVIVPVISVAVRKFGRFLRELSHQTQXX 352 ++ + + L + + S+ + + + + +V + R ++ Sbjct: 242 LHIIPITLEIAMVSGILTYKYGPSFSAIAATTVALYALFTVRTTSWRTVFRRQANAADSK 301 Query: 353 XXXXXXXXXXXFGAIRTVRAFAQEPHEISRYGGKVNETLKLGLKQAKVVGLFSGG 517 + A++T F E +E+SRY ++ K +K A + + G Sbjct: 302 ASAAAIESLINYEAVKT---FNNESYEMSRYEKHLSAYEKANVKVASSLAFLNSG 353
>CVAB_ECOLI (P22520) Colicin V secretion/processing ATP-binding protein cvaB| (EC 3.4.22.-) Length = 698 Score = 32.3 bits (72), Expect = 0.88 Identities = 31/177 (17%), Positives = 68/177 (38%) Frame = +2 Query: 5 LRAWLFNSASERVVARLRQDLFSHLINQEIAFFDVTRTGELLSRLSEDTQIIKNAATTNL 184 LRAW S + + + LF HL+ +AFF+ + G++ SR + T+ + Sbjct: 233 LRAWSSLVMSTLINVQWQSGLFDHLLRLPLAFFERRKLGDIQSRFDSLDTLRATFTTSVI 292 Query: 185 SEALRNLTTTAIGLGFMFSTSWKLTLLALVIVPVISVAVRKFGRFLRELSHQTQXXXXXX 364 + ++ + + + + ++ I + + +G + R++S + Sbjct: 293 GFIMDSIMVVGVCVMMLLYGGYLTWIVLCFTTIYIFIRLVTYGNY-RQISEECLVREARA 351 Query: 365 XXXXXXXFGAIRTVRAFAQEPHEISRYGGKVNETLKLGLKQAKVVGLFSGGLNAAST 535 I TV+ + + + + G+K ++ LF GG+N T Sbjct: 352 ASYFMETLYGIATVKIQGMVGIRGAHWLNMKIDAINSGIKLTRMDLLF-GGINTFVT 407
>YAWB_SCHPO (Q10185) Probable ATP-dependent permease C3F10.11c| Length = 1478 Score = 32.3 bits (72), Expect = 0.88 Identities = 26/129 (20%), Positives = 47/129 (36%) Frame = +2 Query: 53 LRQDLFSHLINQEIAFFDVTRTGELLSRLSEDTQIIKNAATTNLSEALRNLTTTAIGLGF 232 L + ++ ++FF+ T TG +L+R S D + + RNL L Sbjct: 992 LHDSMVKAVLRAPMSFFETTPTGRILNRFSSDVYRVDEVISRVFMFFFRNLFQIVFVLAV 1051 Query: 233 MFSTSWKLTLLALVIVPVISVAVRKFGRFLRELSHQTQXXXXXXXXXXXXXFGAIRTVRA 412 + +S +L + + + + + REL G + T+RA Sbjct: 1052 ICYSSPMFMILIVPLFFLYRYNQVYYTQTSRELKRLDSVTRSPLYAHFQESLGGLSTIRA 1111 Query: 413 FAQEPHEIS 439 + E IS Sbjct: 1112 YDMEDTFIS 1120
>NPCL1_HUMAN (Q9UHC9) Niemann-Pick C1-like protein 1 precursor| Length = 1359 Score = 31.6 bits (70), Expect = 1.5 Identities = 17/45 (37%), Positives = 27/45 (60%), Gaps = 4/45 (8%) Frame = +2 Query: 176 TNLSEALRNLTTTAIGLGFM----FSTSWKLTLLALVIVPVISVA 298 T+LS+ L T T +G F + SW LT+L L ++PV+++A Sbjct: 323 TSLSDKLSFSTHTLLGQFFQGWGTWVASWPLTILVLSVIPVVALA 367
>EPIZ_STAEP (P30193) Hypothetical protein in epiA 5'region (Fragment)| Length = 275 Score = 31.6 bits (70), Expect = 1.5 Identities = 18/108 (16%), Positives = 44/108 (40%) Frame = +2 Query: 200 NLTTTAIGLGFMFSTSWKLTLLALVIVPVISVAVRKFGRFLRELSHQTQXXXXXXXXXXX 379 NL + + L F++ + LTL + +P++ + + G ++ +S ++Q Sbjct: 1 NLFSVIVSLIFLYIINKTLTLYLVCTLPILIIVILPIGNIMKRVSSKSQEATAKLSSYYS 60 Query: 380 XXFGAIRTVRAFAQEPHEISRYGGKVNETLKLGLKQAKVVGLFSGGLN 523 I+ ++ + E + + + L + KV+ F +N Sbjct: 61 NRLSTIKLIKTLSTYNIEKIKNYTLLKNIFDIELHKIKVLSFFEPIMN 108
>CFTR_CARPS (Q2QLC5) Cystic fibrosis transmembrane conductance regulator (CFTR)| (cAMP-dependent chloride channel) (ATP-binding cassette transporter sub-family C member 7) Length = 1482 Score = 31.6 bits (70), Expect = 1.5 Identities = 25/129 (19%), Positives = 55/129 (42%), Gaps = 3/129 (2%) Frame = +2 Query: 53 LRQDLFSHLINQEIAFFDVTRTGELLSRLSEDTQIIKNAATTNLSEALRNLTTTAIGLGF 232 L + +++ ++ ++ + GE+L+R S+DT I+ + + + ++ I +G Sbjct: 949 LHHKMLHSVLHAPMSTLNMLKAGEILNRFSKDTAILDDLLPLTIFDFIQ---LALIVIGA 1005 Query: 233 MFSTSWKLTLLALVIVPVISVAVRKFGRFL---RELSHQTQXXXXXXXXXXXXXFGAIRT 403 + S + L VPVI+ + FL ++L + T Sbjct: 1006 IAVVSVLQPYIFLATVPVITAFITLRAYFLPTSQQLKQLESEGRSPIFTHLVTSLRGLWT 1065 Query: 404 VRAFAQEPH 430 +RAF ++P+ Sbjct: 1066 LRAFGRQPY 1074
>DPOL_METJA (Q58295) DNA polymerase (EC 2.7.7.7) [Contains: Mja pol-1 intein; Mja| pol-2 intein] Length = 1634 Score = 30.4 bits (67), Expect = 3.3 Identities = 15/29 (51%), Positives = 17/29 (58%) Frame = +2 Query: 422 EPHEISRYGGKVNETLKLGLKQAKVVGLF 508 E EI Y GK+N LKL K AK +G F Sbjct: 1139 EDCEIGAYSGKINALLKLDEKLAKFLGFF 1167
>E13B_BACCI (P23903) Glucan endo-1,3-beta-glucosidase A1 precursor (EC| 3.2.1.39) ((1->3)-beta-glucan endohydrolase) ((1->3)-beta-glucanase A1) Length = 682 Score = 30.0 bits (66), Expect = 4.4 Identities = 17/58 (29%), Positives = 26/58 (44%), Gaps = 1/58 (1%) Frame = +2 Query: 326 ELSHQTQXXXXXXXXXXXXXFGAIRTVRAFAQEPHEISRY-GGKVNETLKLGLKQAKV 496 EL H T A+ ++F Q+P+ ++Y GK+N KL LK +V Sbjct: 462 ELQHYTNSTQNVYVQDGKLNIKAMNDSKSFPQDPNRYAQYSSGKINTKDKLSLKYGRV 519
>DPO5_YEAST (P39985) DNA polymerase V (EC 2.7.7.7) (POL V)| Length = 1022 Score = 29.6 bits (65), Expect = 5.7 Identities = 15/44 (34%), Positives = 26/44 (59%) Frame = +2 Query: 110 TRTGELLSRLSEDTQIIKNAATTNLSEALRNLTTTAIGLGFMFS 241 + G+L++ L E+ + IKN A + LS+ R+ T + GL + S Sbjct: 570 SHVGDLINPLDENLENIKNEAISCLSKVCRSRTAQSWGLSTLLS 613
>VIRB4_AGRTU (P0A3W0) Protein virB4 precursor| Length = 789 Score = 29.6 bits (65), Expect = 5.7 Identities = 23/75 (30%), Positives = 32/75 (42%) Frame = +2 Query: 41 VVARLRQDLFSHLINQEIAFFDVTRTGELLSRLSEDTQIIKNAATTNLSEALRNLTTTAI 220 V+A L Q + + FFD R GELL R + T + T + LR L TA Sbjct: 446 VLAMLEQSMVDRA--GTVVFFDKDRGGELLVRATGGTYLALRRGTPSGLAPLRGLENTAA 503 Query: 221 GLGFMFSTSWKLTLL 265 F+ W + L+ Sbjct: 504 SHDFL--REWIVALI 516
>VIRB4_AGRT9 (P0A3W1) Protein virB4 precursor| Length = 789 Score = 29.6 bits (65), Expect = 5.7 Identities = 23/75 (30%), Positives = 32/75 (42%) Frame = +2 Query: 41 VVARLRQDLFSHLINQEIAFFDVTRTGELLSRLSEDTQIIKNAATTNLSEALRNLTTTAI 220 V+A L Q + + FFD R GELL R + T + T + LR L TA Sbjct: 446 VLAMLEQSMVDRA--GTVVFFDKDRGGELLVRATGGTYLALRRGTPSGLAPLRGLENTAA 503 Query: 221 GLGFMFSTSWKLTLL 265 F+ W + L+ Sbjct: 504 SHDFL--REWIVALI 516
>CI076_HUMAN (Q9H9A7) Protein C9orf76| Length = 625 Score = 29.6 bits (65), Expect = 5.7 Identities = 15/56 (26%), Positives = 30/56 (53%), Gaps = 6/56 (10%) Frame = -3 Query: 407 LLCEWHQKIPQLWMK-----LQQPQLVSDVKAHEENAQIYAQQLIS-LEQLQVPTM 258 LL WH K+P +W++ +Q+ ++ + N Q++ Q L++ L L+ P + Sbjct: 14 LLAAWHVKVPPMWLEACINWIQEENNNVNLSQAQMNKQVFEQWLLTDLRDLEHPLL 69
>Y395_PASMU (Q9CNN2) UPF0319 protein PM0395 precursor| Length = 218 Score = 29.3 bits (64), Expect = 7.5 Identities = 21/74 (28%), Positives = 38/74 (51%), Gaps = 7/74 (9%) Frame = -2 Query: 306 LRTATDITGTITSANNVSFHEVENMKPRPIAVVVRLRSAS------ERFVVAAFFIIWVS 145 L + + G +TS++N+ F ++ KP +++ RS + + VV II Sbjct: 14 LTSTVSVAGVVTSSSNIDFLAIDGQKPSK-SLLKEKRSFNVSDTLPHQVVVRVAEIIRTG 72 Query: 144 SE-SLLKSSPVLVT 106 S+ SL +S P++VT Sbjct: 73 SDRSLYESDPIVVT 86
>Y1383_MYCBO (P63392) Hypothetical ABC transporter ATP-binding protein Mb1383| Length = 859 Score = 29.3 bits (64), Expect = 7.5 Identities = 20/88 (22%), Positives = 38/88 (43%) Frame = +2 Query: 2 ALRAWLFNSASERVVARLRQDLFSHLINQEIAFFDVTRTGELLSRLSEDTQIIKNAATTN 181 AL WL + R LR L S L + +F +G + +++DT + T Sbjct: 350 ALTLWL-HVIDARFARALRLRLLSKLSRLPLGWFTSRGSGSIKKLVTDDTLALHYLVTHA 408 Query: 182 LSEALRNLTTTAIGLGFMFSTSWKLTLL 265 + +A+ + L ++F W++ L+ Sbjct: 409 VPDAVAAVVAPVGVLVYLFVVDWRVALV 436
>Y1348_MYCTU (P63391) Hypothetical ABC transporter ATP-binding protein| Rv1348/MT1390 Length = 859 Score = 29.3 bits (64), Expect = 7.5 Identities = 20/88 (22%), Positives = 38/88 (43%) Frame = +2 Query: 2 ALRAWLFNSASERVVARLRQDLFSHLINQEIAFFDVTRTGELLSRLSEDTQIIKNAATTN 181 AL WL + R LR L S L + +F +G + +++DT + T Sbjct: 350 ALTLWL-HVIDARFARALRLRLLSKLSRLPLGWFTSRGSGSIKKLVTDDTLALHYLVTHA 408 Query: 182 LSEALRNLTTTAIGLGFMFSTSWKLTLL 265 + +A+ + L ++F W++ L+ Sbjct: 409 VPDAVAAVVAPVGVLVYLFVVDWRVALV 436
>CASP4_HUMAN (P49662) Caspase-4 precursor (EC 3.4.22.-) (CASP-4) (ICH-2| protease) (TX protease) (ICE(rel)-II) [Contains: Caspase-4 subunit 1; Caspase-4 subunit 2] Length = 377 Score = 28.9 bits (63), Expect = 9.7 Identities = 16/48 (33%), Positives = 22/48 (45%) Frame = +2 Query: 68 FSHLINQEIAFFDVTRTGELLSRLSEDTQIIKNAATTNLSEALRNLTT 211 F HL + A FD+T ELL L + +N ++ ALR T Sbjct: 146 FDHLPPRNGADFDITGMKELLEGLDYSVDVEENLTARDMESALRAFAT 193
>AAEB_ERWCT (Q6DAH4) p-hydroxybenzoic acid efflux pump subunit aaeB (pHBA| efflux pump protein B) Length = 662 Score = 28.9 bits (63), Expect = 9.7 Identities = 19/59 (32%), Positives = 32/59 (54%), Gaps = 3/59 (5%) Frame = +2 Query: 137 LSEDTQIIKNAATTN--LSEALRNLTTTAIGLGFMFSTSWKLTLLALVIVPVI-SVAVR 304 L+ D +I +A T+ + LR TA+G F ST W + +V++ V+ S+A+R Sbjct: 346 LNSDVEIKAPSAETHHAMINGLRTGVATALGCLFWLSTGWTSGSVCMVMIAVVTSLAMR 404 Database: uniprot_sprot.fasta Posted date: May 25, 2006 5:36 PM Number of letters in database: 80,573,946 Number of sequences in database: 219,361 Lambda K H 0.318 0.135 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 66,800,933 Number of Sequences: 219361 Number of extensions: 1151542 Number of successful extensions: 3845 Number of sequences better than 10.0: 172 Number of HSP's better than 10.0 without gapping: 3674 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 3782 length of database: 80,573,946 effective HSP length: 105 effective length of database: 57,541,041 effective search space used: 4315578075 frameshift window, decay const: 50, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
