ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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更新日:2016年5月1日

Clone Information

BLAST Search Result

Clone Name baak4c12
Clone Library Name barley_pub

No. Definition Score
(bits)
E
Value
1KPYC_SOLTU (P22200) Pyruvate kinase, cytosolic isozyme (EC 2.7.1... 233 2e-61
2KPYC_SOYBN (Q42806) Pyruvate kinase, cytosolic isozyme (EC 2.7.1... 229 5e-60
3KPYC_TOBAC (Q42954) Pyruvate kinase, cytosolic isozyme (EC 2.7.1... 197 2e-50
4KPYC_ARATH (O65595) Probable pyruvate kinase, cytosolic isozyme ... 184 1e-46
5KPYK1_CANGA (Q6FIS9) Pyruvate kinase 1 (EC 2.7.1.40) (PK 1) 68 2e-11
6KPYK_EIMTE (O44006) Pyruvate kinase (EC 2.7.1.40) (PK) 66 7e-11
7KPYK_XENLA (Q92122) Pyruvate kinase muscle isozyme (EC 2.7.1.40)... 65 1e-10
8KPYK_SACKL (Q875S4) Pyruvate kinase (EC 2.7.1.40) (PK) 65 2e-10
9KPYK_DROME (O62619) Pyruvate kinase (EC 2.7.1.40) (PK) 64 4e-10
10KPYR_CANFA (Q29536) Pyruvate kinase isozyme R (EC 2.7.1.40) (Fra... 63 6e-10
11KPYK_SACCA (Q875Z9) Pyruvate kinase (EC 2.7.1.40) (PK) 63 6e-10
12KPYM_RAT (P11980) Pyruvate kinase isozymes M1/M2 (EC 2.7.1.40) (... 63 7e-10
13KPYM_HUMAN (P14618) Pyruvate kinase isozymes M1/M2 (EC 2.7.1.40)... 63 7e-10
14KPYK2_CANGA (Q6FV12) Pyruvate kinase 2 (EC 2.7.1.40) (PK 2) 63 7e-10
15KPYR_MOUSE (P53657) Pyruvate kinase isozymes R/L (EC 2.7.1.40) (... 63 7e-10
16KPYR_HUMAN (P30613) Pyruvate kinase isozymes R/L (EC 2.7.1.40) (... 62 1e-09
17KPYM_MOUSE (P52480) Pyruvate kinase isozyme M2 (EC 2.7.1.40) 62 1e-09
18KPYR_RAT (P12928) Pyruvate kinase isozymes R/L (EC 2.7.1.40) (L-PK) 62 2e-09
19KPYM_PONPY (Q5NVN0) Pyruvate kinase isozyme M1 (EC 2.7.1.40) 61 2e-09
20KPYK1_YEAST (P00549) Pyruvate kinase 1 (EC 2.7.1.40) (PK 1) 61 2e-09
21KPYK2_TRYBB (P30616) Pyruvate kinase 2 (EC 2.7.1.40) (PK 2) 61 3e-09
22KPYK1_TRYBB (P30615) Pyruvate kinase 1 (EC 2.7.1.40) (PK 1) 61 3e-09
23KPYK_KLULA (Q875M9) Pyruvate kinase (EC 2.7.1.40) (PK) 60 5e-09
24KPYK_CHICK (P00548) Pyruvate kinase muscle isozyme (EC 2.7.1.40) 60 5e-09
25KPYM_FELCA (P11979) Pyruvate kinase isozyme M1 (EC 2.7.1.40) (Py... 59 1e-08
26KPYK_YARLI (P30614) Pyruvate kinase (EC 2.7.1.40) (PK) 59 1e-08
27KPYM_RABIT (P11974) Pyruvate kinase isozymes M1/M2 (EC 2.7.1.40)... 58 2e-08
28KPYK_DEBHA (Q6BS75) Pyruvate kinase (EC 2.7.1.40) (PK) 58 2e-08
29KPYK_ASHGO (Q759A9) Pyruvate kinase (EC 2.7.1.40) (PK) 57 3e-08
30KPYK_TRIRE (P31865) Pyruvate kinase (EC 2.7.1.40) (PK) 54 3e-07
31KPYK2_YEAST (P52489) Pyruvate kinase 2 (EC 2.7.1.40) (PK 2) 54 4e-07
32KPYK_LEIME (Q27686) Pyruvate kinase (EC 2.7.1.40) (PK) 54 4e-07
33KPYK_NEUCR (Q7RVA8) Pyruvate kinase (EC 2.7.1.40) (PK) 54 4e-07
34KPYK_BACSU (P80885) Pyruvate kinase (EC 2.7.1.40) (PK) (Vegetati... 53 6e-07
35KPYK_ASPNG (Q12669) Pyruvate kinase (EC 2.7.1.40) (PK) 53 8e-07
36KPYK_BACPY (P51182) Pyruvate kinase (EC 2.7.1.40) (PK) 52 1e-06
37KPYK_EMENI (P22360) Pyruvate kinase (EC 2.7.1.40) (PK) 52 1e-06
38KPYK_LACLA (Q07637) Pyruvate kinase (EC 2.7.1.40) (PK) 50 4e-06
39KPYK_SCHPO (Q10208) Pyruvate kinase (EC 2.7.1.40) (PK) 50 4e-06
40KPYK1_SALTI (Q8Z6K2) Pyruvate kinase I (EC 2.7.1.40) (PK-1) 50 5e-06
41KPYK_CLOPE (Q46289) Pyruvate kinase (EC 2.7.1.40) (PK) 50 6e-06
42KPYK1_ECOLI (P0AD61) Pyruvate kinase I (EC 2.7.1.40) (PK-1) 50 6e-06
43KPYK1_ECO57 (P0AD62) Pyruvate kinase I (EC 2.7.1.40) (PK-1) 50 6e-06
44KPYK1_SALTY (P77983) Pyruvate kinase I (EC 2.7.1.40) (PK-1) 49 8e-06
45KPYK_BACST (Q02499) Pyruvate kinase (EC 2.7.1.40) (PK) 49 8e-06
46KPYK_TRYBO (Q27788) Pyruvate kinase (EC 2.7.1.40) (PK) 49 1e-05
47KPYK_BACLI (P51181) Pyruvate kinase (EC 2.7.1.40) (PK) 48 2e-05
48KPYK_AGABI (O94122) Pyruvate kinase (EC 2.7.1.40) (PK) 48 2e-05
49KPYK_LACDE (P34038) Pyruvate kinase (EC 2.7.1.40) (PK) 47 3e-05
50KPYK2_SYNY3 (P73534) Pyruvate kinase 2 (EC 2.7.1.40) (PK 2) 46 7e-05
51KPYK_CLOAB (O08309) Pyruvate kinase (EC 2.7.1.40) (PK) 45 2e-04
52KPYK_CHLMU (Q9PK61) Pyruvate kinase (EC 2.7.1.40) (PK) 44 5e-04
53KPYK1_AGRVI (P70789) Pyruvate kinase (EC 2.7.1.40) (PK) 42 0.001
54KPYK_CHLTR (P94685) Pyruvate kinase (EC 2.7.1.40) (PK) 42 0.001
55KPYK_THEAC (P32044) Pyruvate kinase (EC 2.7.1.40) (PK) 40 0.007
56KPYK_CHLPN (Q9Z984) Pyruvate kinase (EC 2.7.1.40) (PK) 38 0.025
57KPYK2_AGRVI (Q44473) Pyruvate kinase (EC 2.7.1.40) (PK) 37 0.056
58CO3A1_HUMAN (P02461) Collagen alpha-1(III) chain precursor 32 0.19
59HLDE_SALTY (Q7CPR9) Bifunctional protein hldE [Includes: D-beta-... 35 0.21
60HLDE_SALTI (Q8XEW9) Bifunctional protein hldE [Includes: D-beta-... 35 0.21
61COL2_CAEEL (P17656) Cuticle collagen 2 precursor 33 0.48
62VE1_HPV10 (P36720) Replication protein E1 (EC 3.6.1.-) (ATP-depe... 33 0.62
63CO1A2_RABIT (Q28668) Collagen alpha-2(I) chain precursor (Fragment) 33 0.81
64CO6A2_MOUSE (Q02788) Collagen alpha-2(VI) chain precursor 33 0.81
65ATX7_HUMAN (O15265) Ataxin-7 (Spinocerebellar ataxia type 7 prot... 32 1.1
66HYDL_STRCO (P42534) Putative polyketide hydroxylase (EC 1.14.13.... 32 1.1
67IF2_CORDI (Q6NGN2) Translation initiation factor IF-2 32 1.8
68BCOR_HUMAN (Q6W2J9) BCoR protein (BCL-6 corepressor) 32 1.8
69LAMC2_HUMAN (Q13753) Laminin gamma-2 chain precursor (Laminin 5 ... 31 2.4
70HLDE_ECOLI (P76658) Bifunctional protein hldE [Includes: D-beta-... 31 2.4
71HLDE_ECOL6 (Q8FDH5) Bifunctional protein hldE [Includes: D-beta-... 31 2.4
72HLDE_ECO57 (Q7AAQ7) Bifunctional protein hldE [Includes: D-beta-... 31 2.4
735E5_RAT (Q63003) 5E5 antigen 31 2.4
74CO1A1_CHICK (P02457) Collagen alpha-1(I) chain precursor 31 2.4
75CO1A1_BOVIN (P02453) Collagen alpha-1(I) chain (Fragments) 31 3.1
76YNU8_YEAST (P40159) Protein YNL208W 31 3.1
77IE63_HHV2H (P28276) Transcriptional regulator IE63 (VMW63) (ICP27) 31 3.1
78ATS1_HUMAN (Q9UHI8) ADAMTS-1 precursor (EC 3.4.24.-) (A disinteg... 31 3.1
79HLDE_YERPE (Q8ZI60) Bifunctional protein hldE [Includes: D-beta-... 30 4.0
80HLDE_SHIFL (Q7UBI8) Bifunctional protein hldE [Includes: D-beta-... 30 4.0
81COHA1_CHICK (Q90584) Collagen alpha-1(XVII) chain (Bullous pemph... 30 4.0
82CO1A1_RAT (P02454) Collagen alpha-1(I) chain precursor 30 4.0
83CO1A1_MOUSE (P11087) Collagen alpha-1(I) chain precursor 30 4.0
84EBNA1_EBV (P03211) Epstein-Barr nuclear antigen 1 (EBV nuclear a... 30 4.0
85IE63_HHV1E (P36295) Transcriptional regulator IE63 (VMW63) (ICP27) 30 5.3
86NOLC_RHIFR (P26508) Protein nolC 30 5.3
87CO1A1_CANFA (Q9XSJ7) Collagen alpha-1(I) chain precursor 30 5.3
88CO3A1_BOVIN (P04258) Collagen alpha-1(III) chain 30 5.3
89OSA_DROME (Q8IN94) Trithorax group protein osa (Protein eyelid) 30 5.3
90CO1A1_HUMAN (P02452) Collagen alpha-1(I) chain precursor 30 5.3
91LAMC2_HORSE (Q8HZI9) Laminin gamma-2 chain precursor (Laminin 5 ... 30 6.9
92KPYK_METEX (O05118) Pyruvate kinase (EC 2.7.1.40) (PK) 30 6.9
93PO4F1_HUMAN (Q01851) POU domain, class 4, transcription factor 1... 30 6.9
94VG16_BPP22 (Q01146) DNA transfer protein gp16 29 9.0
95NONA_DROME (Q04047) Protein no-on-transient A (Puff-specific pro... 29 9.0
96CLIC6_MOUSE (Q8BHB9) Chloride intracellular channel 6 29 9.0
97ACON_STAAW (P63434) Aconitate hydratase (EC 4.2.1.3) (Citrate hy... 29 9.0
98ACON_STAAS (Q6G9K9) Aconitate hydratase (EC 4.2.1.3) (Citrate hy... 29 9.0
99ACON_STAAR (Q6GH55) Aconitate hydratase (EC 4.2.1.3) (Citrate hy... 29 9.0
100ACON_STAAN (P99148) Aconitate hydratase (EC 4.2.1.3) (Citrate hy... 29 9.0
101ACON_STAAM (P63433) Aconitate hydratase (EC 4.2.1.3) (Citrate hy... 29 9.0
102ACON_STAAC (Q5HG69) Aconitate hydratase (EC 4.2.1.3) (Citrate hy... 29 9.0
103CI010_HUMAN (Q9NZB2) Protein C9orf10 29 9.0

>KPYC_SOLTU (P22200) Pyruvate kinase, cytosolic isozyme (EC 2.7.1.40) (PK)|
          Length = 510

 Score =  233 bits (595), Expect = 2e-61
 Identities = 122/143 (85%), Positives = 129/143 (90%)
 Frame = +1

Query: 34  MIKAAPLPMSPLESLASSAVRTANKARATLIVVLTRGGTTAKLVAKYRPRVPILSVVVPV 213
           MI+  PLPMSPLESLASSAVRTANKARA LIVVLTRGG+TAKLVAKYRP VPILSVVVPV
Sbjct: 368 MIRCTPLPMSPLESLASSAVRTANKARAKLIVVLTRGGSTAKLVAKYRPAVPILSVVVPV 427

Query: 214 LTTDSFDWTISSEGPARHSLIYRGLIPLLAEGSAKATDSESTEEILQAALKSAVKKQLCK 393
           LTTDSFDW+IS E PARHSL+YRGLIPLL EGSAKATDSESTE IL+AALKSAV + LCK
Sbjct: 428 LTTDSFDWSISDETPARHSLVYRGLIPLLGEGSAKATDSESTEVILEAALKSAVTRGLCK 487

Query: 394 AGDAVVVLHRIGVASVIKICTVQ 462
            GDAVV LHRIG ASVIKIC V+
Sbjct: 488 PGDAVVALHRIGSASVIKICVVK 510



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>KPYC_SOYBN (Q42806) Pyruvate kinase, cytosolic isozyme (EC 2.7.1.40) (PK)|
          Length = 511

 Score =  229 bits (584), Expect = 5e-60
 Identities = 118/143 (82%), Positives = 129/143 (90%)
 Frame = +1

Query: 34  MIKAAPLPMSPLESLASSAVRTANKARATLIVVLTRGGTTAKLVAKYRPRVPILSVVVPV 213
           MI++ PLPMSPLESLASSAVRTANKA+A LIVVLTRGG+TAKLVAKYRP VPILSVVVPV
Sbjct: 369 MIRSTPLPMSPLESLASSAVRTANKAKAKLIVVLTRGGSTAKLVAKYRPAVPILSVVVPV 428

Query: 214 LTTDSFDWTISSEGPARHSLIYRGLIPLLAEGSAKATDSESTEEILQAALKSAVKKQLCK 393
           L+TDSFDWT S E PARHSLIYRGLIP+L EGSAKATD+ESTE IL+AALKSA ++ LCK
Sbjct: 429 LSTDSFDWTCSDETPARHSLIYRGLIPILGEGSAKATDAESTEVILEAALKSATERALCK 488

Query: 394 AGDAVVVLHRIGVASVIKICTVQ 462
            GDAVV LHRIG ASVIKIC V+
Sbjct: 489 PGDAVVALHRIGAASVIKICIVK 511



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>KPYC_TOBAC (Q42954) Pyruvate kinase, cytosolic isozyme (EC 2.7.1.40) (PK)|
          Length = 508

 Score =  197 bits (500), Expect = 2e-50
 Identities = 101/139 (72%), Positives = 116/139 (83%)
 Frame = +1

Query: 46  APLPMSPLESLASSAVRTANKARATLIVVLTRGGTTAKLVAKYRPRVPILSVVVPVLTTD 225
           AP+PMSPLESLASSAVRTAN A+A LI+VLTRGG+TAKLVAKYRP +PILSVVVP + TD
Sbjct: 370 APVPMSPLESLASSAVRTANSAKAALILVLTRGGSTAKLVAKYRPGMPILSVVVPEIKTD 429

Query: 226 SFDWTISSEGPARHSLIYRGLIPLLAEGSAKATDSESTEEILQAALKSAVKKQLCKAGDA 405
           SFDWT S E PARHSLI+RGL+P+L  GSA+A+  ESTEE L  AL+ A  K LCK GD+
Sbjct: 430 SFDWTCSDESPARHSLIFRGLVPVLHAGSARASHEESTEEALDFALQHAKTKGLCKQGDS 489

Query: 406 VVVLHRIGVASVIKICTVQ 462
           VV LHR+G ASVIKI TV+
Sbjct: 490 VVALHRVGTASVIKIVTVK 508



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>KPYC_ARATH (O65595) Probable pyruvate kinase, cytosolic isozyme (EC 2.7.1.40)|
           (PK)
          Length = 497

 Score =  184 bits (468), Expect = 1e-46
 Identities = 95/139 (68%), Positives = 114/139 (82%)
 Frame = +1

Query: 46  APLPMSPLESLASSAVRTANKARATLIVVLTRGGTTAKLVAKYRPRVPILSVVVPVLTTD 225
           A +PMSP+ESLASSAVRTA  +RATL++VLTRGG+TA+LVAKYRP +PILSVVVP +T+D
Sbjct: 359 AAVPMSPMESLASSAVRTATSSRATLMMVLTRGGSTARLVAKYRPGIPILSVVVPEITSD 418

Query: 226 SFDWTISSEGPARHSLIYRGLIPLLAEGSAKATDSESTEEILQAALKSAVKKQLCKAGDA 405
           SFDW  S+E PARHSLIYRGL+P+L  GSA+A+  ESTEE L+ A +   KKQLCK GD+
Sbjct: 419 SFDWACSNEAPARHSLIYRGLVPVLYAGSARASIDESTEETLEFASEYGKKKQLCKTGDS 478

Query: 406 VVVLHRIGVASVIKICTVQ 462
           VV L R G A VIKI TV+
Sbjct: 479 VVALFRTGNAIVIKILTVK 497



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>KPYK1_CANGA (Q6FIS9) Pyruvate kinase 1 (EC 2.7.1.40) (PK 1)|
          Length = 501

 Score = 68.2 bits (165), Expect = 2e-11
 Identities = 44/140 (31%), Positives = 72/140 (51%), Gaps = 4/140 (2%)
 Frame = +1

Query: 49  PLPMSPLESLASSAVRTANKARATLIVVLTRGGTTAKLVAKYRPRVPILSVVVPVLTTDS 228
           P P S  E++A+SAV    + +A  I+VL+  GTTA+LV+KYRP  PI+ V     T   
Sbjct: 374 PKPTSTTETVAASAVAAVFEQKAKAIIVLSTSGTTARLVSKYRPNCPIILVTRNART--- 430

Query: 229 FDWTISSEGPARHSLIYRGLIPLLAEGSAKATDSESTEEILQAALKSAVKKQLCKAGDAV 408
                     AR S +YRG+ P + E  + +  +E  E  L   ++ A++  + K GD  
Sbjct: 431 ----------ARFSHLYRGVFPFVYEKESVSDWTEDVEARLNFGIEQAIEFGILKKGDTY 480

Query: 409 VVLH----RIGVASVIKICT 456
           V +      +G ++ +++ T
Sbjct: 481 VSIQGFKAGVGHSNTLQVST 500



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>KPYK_EIMTE (O44006) Pyruvate kinase (EC 2.7.1.40) (PK)|
          Length = 531

 Score = 66.2 bits (160), Expect = 7e-11
 Identities = 44/146 (30%), Positives = 76/146 (52%), Gaps = 5/146 (3%)
 Frame = +1

Query: 40  KAAPLPMSPLESLASSAVRTANKARATLIVVLTRGGTTAKLVAKYRPRVPILSVVVPVLT 219
           +A   P+   E++A +AV TA    A+LI+ LT  G TA+L+AKYRP  PIL++      
Sbjct: 405 QATMTPIDTQEAVARAAVETAQSINASLILALTETGRTARLIAKYRPMQPILAL------ 458

Query: 220 TDSFDWTISSEGPARHSLIYRGLIPLLAEGSAKATDSESTEEILQAALKSAVKKQLCKAG 399
                   +SE   +   + RG+   L          + T+++++ AL +A + QL   G
Sbjct: 459 -------SASEETIKQLQVIRGVTTFL------VPTFQGTDQLIRNALSAAKELQLVSEG 505

Query: 400 DAVVVLHRI-----GVASVIKICTVQ 462
           D++V +H I     G ++++K+  V+
Sbjct: 506 DSIVAVHGIKEEVAGWSNLLKVLVVE 531



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>KPYK_XENLA (Q92122) Pyruvate kinase muscle isozyme (EC 2.7.1.40) (Cytosolic|
           thyroid hormone-binding protein) (CTHBP)
          Length = 527

 Score = 65.5 bits (158), Expect = 1e-10
 Identities = 40/134 (29%), Positives = 67/134 (50%)
 Frame = +1

Query: 16  RRLQGXMIKAAPLPMSPLESLASSAVRTANKARATLIVVLTRGGTTAKLVAKYRPRVPIL 195
           R+L   + + +PL   P E+ A  AV  + K  +  I+VLT+ G +A L+++YRPR PI+
Sbjct: 388 RQLFEELRRVSPLTRDPTEATAVGAVEASFKCSSGAIIVLTKSGRSAHLLSRYRPRAPII 447

Query: 196 SVVVPVLTTDSFDWTISSEGPARHSLIYRGLIPLLAEGSAKATDSESTEEILQAALKSAV 375
           SV               +   AR + +YRG+ P+L   +     +E  +  +  A+    
Sbjct: 448 SVT-------------RNGQTARQAHLYRGIFPVLYREAVHEAWAEDVDSRVNFAMDIGK 494

Query: 376 KKQLCKAGDAVVVL 417
            +   K+GD V+VL
Sbjct: 495 ARGFFKSGDVVIVL 508



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>KPYK_SACKL (Q875S4) Pyruvate kinase (EC 2.7.1.40) (PK)|
          Length = 501

 Score = 64.7 bits (156), Expect = 2e-10
 Identities = 40/141 (28%), Positives = 72/141 (51%), Gaps = 4/141 (2%)
 Frame = +1

Query: 49  PLPMSPLESLASSAVRTANKARATLIVVLTRGGTTAKLVAKYRPRVPILSVVVPVLTTDS 228
           P P S  E++A++AV +  + +A  I+VL+  G T +LV+KY+P VPI+ V         
Sbjct: 374 PKPTSTTETIAAAAVSSVFEQKAKAIIVLSTTGDTPRLVSKYKPNVPIVMVT-------- 425

Query: 229 FDWTISSEGPARHSLIYRGLIPLLAEGSAKATDSESTEEILQAALKSAVKKQLCKAGDAV 408
                 +   AR S +YRG+ P + E   ++  ++  E  L   +  A +  + K GD +
Sbjct: 426 -----RNPRAARFSHLYRGVFPFVYESDTESEWTKDVESRLNFGIAKAKEFGMLKEGDTI 480

Query: 409 VVLH----RIGVASVIKICTV 459
           V +      +G ++ +++ TV
Sbjct: 481 VTIQGFAAGVGHSNTLRVLTV 501



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>KPYK_DROME (O62619) Pyruvate kinase (EC 2.7.1.40) (PK)|
          Length = 533

 Score = 63.5 bits (153), Expect = 4e-10
 Identities = 45/132 (34%), Positives = 67/132 (50%), Gaps = 4/132 (3%)
 Frame = +1

Query: 79  ASSAVRTANKARATLIVVLTRGGTTAKLVAKYRPRVPILSVVVPVLTTDSFDWTISSEGP 258
           A +AV  A KA+A+ IVV+T  G +A  V+KYRPR PI++V     T             
Sbjct: 415 AIAAVEAATKAKASAIVVITTSGKSAFQVSKYRPRCPIIAVTRFAQT------------- 461

Query: 259 ARHSLIYRGLIPLLAEGSAKATDSESTEEILQAALKSAVKKQLCKAGDAVVVL----HRI 426
           AR + +YRGL+PL+ +        +  +  +Q  L+   K    K GD+VVV+       
Sbjct: 462 ARQAHLYRGLVPLIYKEPGLGDWLKDVDVRVQFGLQVGKKNGFIKTGDSVVVVTGWKQGS 521

Query: 427 GVASVIKICTVQ 462
           G  + I+I TV+
Sbjct: 522 GFTNTIRIVTVE 533



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>KPYR_CANFA (Q29536) Pyruvate kinase isozyme R (EC 2.7.1.40) (Fragment)|
          Length = 519

 Score = 63.2 bits (152), Expect = 6e-10
 Identities = 41/139 (29%), Positives = 69/139 (49%)
 Frame = +1

Query: 1   ALXQRRRLQGXMIKAAPLPMSPLESLASSAVRTANKARATLIVVLTRGGTTAKLVAKYRP 180
           A    R+L   + +AAPL   P E  A + V  A K  A  I+VLT+ G +A+L+++YRP
Sbjct: 375 AAVYHRQLFEELRRAAPLSRDPTEVTAIATVEAAFKCCAAAIIVLTKTGRSAQLLSRYRP 434

Query: 181 RVPILSVVVPVLTTDSFDWTISSEGPARHSLIYRGLIPLLAEGSAKATDSESTEEILQAA 360
           R  +++V               S   AR + + RG+ PLL     +A  ++  +  +Q  
Sbjct: 435 RAAVIAVT-------------RSAQAARQAHLCRGVFPLLYSEPPEAIWADDVDRRVQFG 481

Query: 361 LKSAVKKQLCKAGDAVVVL 417
           ++S   +   + GD V+V+
Sbjct: 482 IESGKLRGFLRVGDLVIVV 500



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>KPYK_SACCA (Q875Z9) Pyruvate kinase (EC 2.7.1.40) (PK)|
          Length = 501

 Score = 63.2 bits (152), Expect = 6e-10
 Identities = 40/121 (33%), Positives = 62/121 (51%)
 Frame = +1

Query: 49  PLPMSPLESLASSAVRTANKARATLIVVLTRGGTTAKLVAKYRPRVPILSVVVPVLTTDS 228
           P P S  E++A+SAV    + +A  I+VL+  GTT +LV+KYRP  PI+ V         
Sbjct: 374 PKPTSTTETVAASAVAAVYEQKAKAIIVLSTSGTTPRLVSKYRPDCPIILVT-------- 425

Query: 229 FDWTISSEGPARHSLIYRGLIPLLAEGSAKATDSESTEEILQAALKSAVKKQLCKAGDAV 408
                 +   AR S + RG+ P + E  + A  +E  E  L+  ++ A++  + K GD  
Sbjct: 426 -----RNPRAARFSHLSRGVFPFVYEADSVADWTEDVELRLKFGIEKAIEMGVMKKGDTY 480

Query: 409 V 411
           V
Sbjct: 481 V 481



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>KPYM_RAT (P11980) Pyruvate kinase isozymes M1/M2 (EC 2.7.1.40) (Pyruvate|
           kinase muscle isozyme)
          Length = 530

 Score = 62.8 bits (151), Expect = 7e-10
 Identities = 39/134 (29%), Positives = 65/134 (48%)
 Frame = +1

Query: 16  RRLQGXMIKAAPLPMSPLESLASSAVRTANKARATLIVVLTRGGTTAKLVAKYRPRVPIL 195
           R L   + +A+     PLE++A  +V  + K  A  ++VLT  G +A  VA+YRPR PI+
Sbjct: 391 RLLFEELARASSQSTDPLEAMAMGSVEASYKCLAAALIVLTESGRSAHQVARYRPRAPII 450

Query: 196 SVVVPVLTTDSFDWTISSEGPARHSLIYRGLIPLLAEGSAKATDSESTEEILQAALKSAV 375
           +V               +   AR + +YRG+ P+L + +     +E  +  +  A+    
Sbjct: 451 AVT-------------RNPQTARQAHLYRGIFPVLCKDAVLDAWAEDVDLRVNLAMNVGK 497

Query: 376 KKQLCKAGDAVVVL 417
            +   K GD V+VL
Sbjct: 498 ARGFFKKGDVVIVL 511



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>KPYM_HUMAN (P14618) Pyruvate kinase isozymes M1/M2 (EC 2.7.1.40) (Pyruvate|
           kinase muscle isozyme) (Cytosolic thyroid
           hormone-binding protein) (CTHBP) (THBP1)
          Length = 530

 Score = 62.8 bits (151), Expect = 7e-10
 Identities = 38/126 (30%), Positives = 62/126 (49%)
 Frame = +1

Query: 40  KAAPLPMSPLESLASSAVRTANKARATLIVVLTRGGTTAKLVAKYRPRVPILSVVVPVLT 219
           + AP+   P E+ A  AV  + K  +  I+VLT+ G +A  VA+YRPR PI++V      
Sbjct: 399 RLAPITSDPTEATAVGAVEASFKCCSGAIIVLTKSGRSAHQVARYRPRAPIIAVT----- 453

Query: 220 TDSFDWTISSEGPARHSLIYRGLIPLLAEGSAKATDSESTEEILQAALKSAVKKQLCKAG 399
                    +   AR + +YRG+ P+L +   +   +E  +  +  A+     +   K G
Sbjct: 454 --------RNPQTARQAHLYRGIFPVLCKDPVQEAWAEDVDLRVNFAMNVGKARGFFKKG 505

Query: 400 DAVVVL 417
           D V+VL
Sbjct: 506 DVVIVL 511



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>KPYK2_CANGA (Q6FV12) Pyruvate kinase 2 (EC 2.7.1.40) (PK 2)|
          Length = 508

 Score = 62.8 bits (151), Expect = 7e-10
 Identities = 42/121 (34%), Positives = 61/121 (50%)
 Frame = +1

Query: 49  PLPMSPLESLASSAVRTANKARATLIVVLTRGGTTAKLVAKYRPRVPILSVVVPVLTTDS 228
           P P S  E++A+SAV    +  A LI+VL+  G TA+LV+KYRP+ PI+ V         
Sbjct: 374 PKPTSTTETVAASAVAAVQEQGAKLILVLSTSGNTARLVSKYRPQCPIVLVT-------- 425

Query: 229 FDWTISSEGPARHSLIYRGLIPLLAEGSAKATDSESTEEILQAALKSAVKKQLCKAGDAV 408
                 +   AR S ++RG+ P + E       SE T   L+  +  A +    K GDAV
Sbjct: 426 -----RNPRTARFSHLFRGVFPFVYEKEPLDDWSEDTHARLRFGVDMAKEYGFVKNGDAV 480

Query: 409 V 411
           +
Sbjct: 481 I 481



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>KPYR_MOUSE (P53657) Pyruvate kinase isozymes R/L (EC 2.7.1.40) (L-PK)|
          Length = 574

 Score = 62.8 bits (151), Expect = 7e-10
 Identities = 43/157 (27%), Positives = 76/157 (48%), Gaps = 4/157 (2%)
 Frame = +1

Query: 1   ALXQRRRLQGXMIKAAPLPMSPLESLASSAVRTANKARATLIVVLTRGGTTAKLVAKYRP 180
           A    R+L   + +AAPL   P E  A  AV  + K  A  I+VLT+ G +A+L+++YRP
Sbjct: 430 AAVYHRQLFEELRRAAPLSRDPTEVTAIGAVEASFKCCAAAIIVLTKTGRSAQLLSRYRP 489

Query: 181 RVPILSVVVPVLTTDSFDWTISSEGPARHSLIYRGLIPLLAEGSAKATDSESTEEILQAA 360
           R  +++V               S   AR   + RG+ PLL     +A  ++  +  +Q  
Sbjct: 490 RAAVIAVT-------------RSAQAARQVHLSRGVFPLLYREPPEAVWADDVDRRVQFG 536

Query: 361 LKSAVKKQLCKAGDAVVVL----HRIGVASVIKICTV 459
           ++S   +   + GD V+V+       G  +++++ T+
Sbjct: 537 IESGKLRGFLRVGDLVIVVTGWRPGSGYTNIMRVLTI 573



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>KPYR_HUMAN (P30613) Pyruvate kinase isozymes R/L (EC 2.7.1.40) (R-type/L-type|
           pyruvate kinase) (Red cell/liver pyruvate kinase)
          Length = 574

 Score = 62.0 bits (149), Expect = 1e-09
 Identities = 42/139 (30%), Positives = 67/139 (48%)
 Frame = +1

Query: 1   ALXQRRRLQGXMIKAAPLPMSPLESLASSAVRTANKARATLIVVLTRGGTTAKLVAKYRP 180
           A    R+L   + +AAPL   P E  A  AV  A K  A  I+VLT  G +A+L+++YRP
Sbjct: 430 AAVYHRQLFEELRRAAPLSRDPTEVTAIGAVEAAFKCCAAAIIVLTTTGRSAQLLSRYRP 489

Query: 181 RVPILSVVVPVLTTDSFDWTISSEGPARHSLIYRGLIPLLAEGSAKATDSESTEEILQAA 360
           R  +++V               S   AR   + RG+ PLL     +A  ++  +  +Q  
Sbjct: 490 RAAVIAVT-------------RSAQAARQVHLCRGVFPLLYREPPEAIWADDVDRRVQFG 536

Query: 361 LKSAVKKQLCKAGDAVVVL 417
           ++S   +   + GD V+V+
Sbjct: 537 IESGKLRGFLRVGDLVIVV 555



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>KPYM_MOUSE (P52480) Pyruvate kinase isozyme M2 (EC 2.7.1.40)|
          Length = 530

 Score = 62.0 bits (149), Expect = 1e-09
 Identities = 38/126 (30%), Positives = 62/126 (49%)
 Frame = +1

Query: 40  KAAPLPMSPLESLASSAVRTANKARATLIVVLTRGGTTAKLVAKYRPRVPILSVVVPVLT 219
           + AP+   P E+ A  AV  + K  +  I+VLT+ G +A  VA+YRPR PI++V      
Sbjct: 399 RLAPITSDPTEAAAVGAVEASFKCCSGAIIVLTKSGRSAHQVARYRPRAPIIAVT----- 453

Query: 220 TDSFDWTISSEGPARHSLIYRGLIPLLAEGSAKATDSESTEEILQAALKSAVKKQLCKAG 399
                    +   AR + +YRG+ P+L + +     +E  +  +  A+     +   K G
Sbjct: 454 --------RNPQTARQAHLYRGIFPVLCKDAVLNAWAEDVDLRVNLAMDVGKARGFFKKG 505

Query: 400 DAVVVL 417
           D V+VL
Sbjct: 506 DVVIVL 511



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>KPYR_RAT (P12928) Pyruvate kinase isozymes R/L (EC 2.7.1.40) (L-PK)|
          Length = 574

 Score = 61.6 bits (148), Expect = 2e-09
 Identities = 41/139 (29%), Positives = 68/139 (48%)
 Frame = +1

Query: 1   ALXQRRRLQGXMIKAAPLPMSPLESLASSAVRTANKARATLIVVLTRGGTTAKLVAKYRP 180
           A    R+L   + +AAPL   P E  A  AV  + K  A  I+VLT+ G +A+L+++YRP
Sbjct: 430 AAVYHRQLFEELRRAAPLSRDPTEVTAIGAVEASFKCCAAAIIVLTKTGRSAQLLSQYRP 489

Query: 181 RVPILSVVVPVLTTDSFDWTISSEGPARHSLIYRGLIPLLAEGSAKATDSESTEEILQAA 360
           R  +++V               S   AR   + RG+ PLL     +A  ++  +  +Q  
Sbjct: 490 RAAVIAVT-------------RSAQAARQVHLSRGVFPLLYREPPEAIWADDVDRRVQFG 536

Query: 361 LKSAVKKQLCKAGDAVVVL 417
           ++S   +   + GD V+V+
Sbjct: 537 IESGKLRGFLRVGDLVIVV 555



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>KPYM_PONPY (Q5NVN0) Pyruvate kinase isozyme M1 (EC 2.7.1.40)|
          Length = 530

 Score = 61.2 bits (147), Expect = 2e-09
 Identities = 37/134 (27%), Positives = 66/134 (49%)
 Frame = +1

Query: 16  RRLQGXMIKAAPLPMSPLESLASSAVRTANKARATLIVVLTRGGTTAKLVAKYRPRVPIL 195
           R+L   +++A+      +E++A  +V  + K  A  ++VLT  G +A  VA+YRPR PI+
Sbjct: 391 RKLFEELVRASSHSTDLMEAMAMGSVEASYKCLAAALIVLTESGRSAHQVARYRPRAPII 450

Query: 196 SVVVPVLTTDSFDWTISSEGPARHSLIYRGLIPLLAEGSAKATDSESTEEILQAALKSAV 375
           +V               +   AR + +YRG+ P+L +   +   +E  +  +  A+    
Sbjct: 451 AVT-------------RNPQTARQAHLYRGIFPVLCKDPVQEAWAEDVDLRVNFAMNVGK 497

Query: 376 KKQLCKAGDAVVVL 417
            +   K GD V+VL
Sbjct: 498 ARGFFKKGDVVIVL 511



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>KPYK1_YEAST (P00549) Pyruvate kinase 1 (EC 2.7.1.40) (PK 1)|
          Length = 500

 Score = 61.2 bits (147), Expect = 2e-09
 Identities = 42/146 (28%), Positives = 69/146 (47%), Gaps = 4/146 (2%)
 Frame = +1

Query: 34  MIKAAPLPMSPLESLASSAVRTANKARATLIVVLTRGGTTAKLVAKYRPRVPILSVVVPV 213
           M    P P S  E++A+SAV    + +A  I+VL+  GTT +LV+KYRP  PI+ V    
Sbjct: 368 MRNCTPKPTSTTETVAASAVAAVFEQKAKAIIVLSTSGTTPRLVSKYRPNCPIILVT--- 424

Query: 214 LTTDSFDWTISSEGPARHSLIYRGLIPLLAEGSAKATDSESTEEILQAALKSAVKKQLCK 393
                          AR S +YRG+ P + E    +  ++  E  +   ++ A +  + K
Sbjct: 425 ----------RCPRAARFSHLYRGVFPFVFEKEPVSDWTDDVEARINFGIEKAKEFGILK 474

Query: 394 AGDAVVVLHRI----GVASVIKICTV 459
            GD  V +       G ++ +++ TV
Sbjct: 475 KGDTYVSIQGFKAGAGHSNTLQVSTV 500



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>KPYK2_TRYBB (P30616) Pyruvate kinase 2 (EC 2.7.1.40) (PK 2)|
          Length = 499

 Score = 60.8 bits (146), Expect = 3e-09
 Identities = 37/123 (30%), Positives = 67/123 (54%)
 Frame = +1

Query: 52  LPMSPLESLASSAVRTANKARATLIVVLTRGGTTAKLVAKYRPRVPILSVVVPVLTTDSF 231
           +PM P E++ SSAV +A + +A  ++VL+  G +A+L++KYRP  PI+ V   + T    
Sbjct: 373 IPMCPEEAVCSSAVASAFEVQAKAMLVLSNTGRSARLISKYRPNCPIICVTTRLQT---- 428

Query: 232 DWTISSEGPARHSLIYRGLIPLLAEGSAKATDSESTEEILQAALKSAVKKQLCKAGDAVV 411
                     R   + R ++ +  + +AK+ + +  E+ ++  L  A K++    GD VV
Sbjct: 429 ---------CRQLNVTRSVVSVFYD-AAKSGEDKDKEKRVKLGLDFAKKEKYASTGDVVV 478

Query: 412 VLH 420
           V+H
Sbjct: 479 VVH 481



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>KPYK1_TRYBB (P30615) Pyruvate kinase 1 (EC 2.7.1.40) (PK 1)|
          Length = 499

 Score = 60.8 bits (146), Expect = 3e-09
 Identities = 37/123 (30%), Positives = 67/123 (54%)
 Frame = +1

Query: 52  LPMSPLESLASSAVRTANKARATLIVVLTRGGTTAKLVAKYRPRVPILSVVVPVLTTDSF 231
           +PM P E++ SSAV +A + +A  ++VL+  G +A+L++KYRP  PI+ V   + T    
Sbjct: 373 IPMCPEEAVCSSAVASAFEVQAKAMLVLSNTGRSARLISKYRPNCPIICVTTRLQT---- 428

Query: 232 DWTISSEGPARHSLIYRGLIPLLAEGSAKATDSESTEEILQAALKSAVKKQLCKAGDAVV 411
                     R   + R ++ +  + +AK+ + +  E+ ++  L  A K++    GD VV
Sbjct: 429 ---------CRQLNVTRSVVSVFYD-AAKSGEDKDKEKRVKLGLDFAKKEKYASTGDVVV 478

Query: 412 VLH 420
           V+H
Sbjct: 479 VVH 481



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>KPYK_KLULA (Q875M9) Pyruvate kinase (EC 2.7.1.40) (PK)|
          Length = 501

 Score = 60.1 bits (144), Expect = 5e-09
 Identities = 38/141 (26%), Positives = 72/141 (51%), Gaps = 4/141 (2%)
 Frame = +1

Query: 49  PLPMSPLESLASSAVRTANKARATLIVVLTRGGTTAKLVAKYRPRVPILSVVVPVLTTDS 228
           P P S  E++A+++V    + +A  ++VL+  G T +LVAKY+P VPI+ V         
Sbjct: 374 PKPTSTTETIAAASVSAVFEQKARALIVLSTTGDTPRLVAKYKPNVPIVMVT-------- 425

Query: 229 FDWTISSEGPARHSLIYRGLIPLLAEGSAKATDSESTEEILQAALKSAVKKQLCKAGDAV 408
                 +   AR S +YRG+ P + + S+ +  +   E+ +   +K A +  +   GD +
Sbjct: 426 -----RNPRAARFSHLYRGVFPFVYDESSDSEWTVDVEKRINFGVKKAKEFGILVDGDTI 480

Query: 409 VVLH----RIGVASVIKICTV 459
           V +      +G ++ +++ TV
Sbjct: 481 VTIQGFAAGVGNSNTLRVLTV 501



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>KPYK_CHICK (P00548) Pyruvate kinase muscle isozyme (EC 2.7.1.40)|
          Length = 529

 Score = 60.1 bits (144), Expect = 5e-09
 Identities = 34/118 (28%), Positives = 60/118 (50%)
 Frame = +1

Query: 64  PLESLASSAVRTANKARATLIVVLTRGGTTAKLVAKYRPRVPILSVVVPVLTTDSFDWTI 243
           P +++A+ AV  + K  A  ++V+T  G +A LV++YRPR PI++V              
Sbjct: 406 PADAMAAGAVEASFKCLAAALIVMTESGRSAHLVSRYRPRAPIIAVT------------- 452

Query: 244 SSEGPARHSLIYRGLIPLLAEGSAKATDSESTEEILQAALKSAVKKQLCKAGDAVVVL 417
            ++  AR + +YRG+ P+L +  A    +E  +  +   +     +   K GD V+VL
Sbjct: 453 RNDQTARQAHLYRGVFPVLCKQPAHDAWAEDVDLRVNLGMNVGKARGFFKTGDLVIVL 510



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>KPYM_FELCA (P11979) Pyruvate kinase isozyme M1 (EC 2.7.1.40) (Pyruvate kinase|
           muscle isozyme)
          Length = 530

 Score = 58.9 bits (141), Expect = 1e-08
 Identities = 35/134 (26%), Positives = 65/134 (48%)
 Frame = +1

Query: 16  RRLQGXMIKAAPLPMSPLESLASSAVRTANKARATLIVVLTRGGTTAKLVAKYRPRVPIL 195
           R+L   +++ +      +E++A  +V  + K  A  ++VLT  G +A  VA+YRPR PI+
Sbjct: 391 RKLFEELVRGSSHSTDLMEAMAMGSVEASYKCLAAALIVLTESGRSAHQVARYRPRAPII 450

Query: 196 SVVVPVLTTDSFDWTISSEGPARHSLIYRGLIPLLAEGSAKATDSESTEEILQAALKSAV 375
           +V               +   AR + +YRG+ P++ +   +   +E  +  +  A+    
Sbjct: 451 AVT-------------RNHQTARQAHLYRGIFPVVCKDPVQEAWAEDVDLRVNLAMNVGK 497

Query: 376 KKQLCKAGDAVVVL 417
            +   K GD V+VL
Sbjct: 498 ARGFFKHGDVVIVL 511



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>KPYK_YARLI (P30614) Pyruvate kinase (EC 2.7.1.40) (PK)|
          Length = 515

 Score = 58.9 bits (141), Expect = 1e-08
 Identities = 41/124 (33%), Positives = 60/124 (48%), Gaps = 3/124 (2%)
 Frame = +1

Query: 55  PMSPLESLASSAVRTANKARATLIVVLTRGGTTAKLVAKYRPRVPILSVVVPVLTTDSFD 234
           P   +E++A SAV  + + +A  I+VL+  GT+A+L +KYRP  PIL V           
Sbjct: 386 PTETVETIAISAVSASFEQQARAIIVLSTSGTSARLCSKYRPNCPILMVT---------- 435

Query: 235 WTISSEGPARHSLIYRGLIPLL---AEGSAKATDSESTEEILQAALKSAVKKQLCKAGDA 405
               +   AR S +YRG+ P +   A  S  A      EE L+  +  AV   +   GD 
Sbjct: 436 ---RNAQAARFSHLYRGVYPFIYHKARASNPAEWQHDVEERLKWGMDEAVALGILNKGDV 492

Query: 406 VVVL 417
           VV +
Sbjct: 493 VVAI 496



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>KPYM_RABIT (P11974) Pyruvate kinase isozymes M1/M2 (EC 2.7.1.40) (Pyruvate|
           kinase muscle isozyme)
          Length = 530

 Score = 58.2 bits (139), Expect = 2e-08
 Identities = 35/134 (26%), Positives = 65/134 (48%)
 Frame = +1

Query: 16  RRLQGXMIKAAPLPMSPLESLASSAVRTANKARATLIVVLTRGGTTAKLVAKYRPRVPIL 195
           R+L   + +++      +E++A  +V  + K  A  ++VLT  G +A  VA+YRPR PI+
Sbjct: 391 RKLFEELARSSSHSTDLMEAMAMGSVEASYKCLAAALIVLTESGRSAHQVARYRPRAPII 450

Query: 196 SVVVPVLTTDSFDWTISSEGPARHSLIYRGLIPLLAEGSAKATDSESTEEILQAALKSAV 375
           +V               +   AR + +YRG+ P++ +   +   +E  +  +  A+    
Sbjct: 451 AVT-------------RNHQTARQAHLYRGIFPVVCKDPVQEAWAEDVDLRVNLAMNVGK 497

Query: 376 KKQLCKAGDAVVVL 417
            +   K GD V+VL
Sbjct: 498 ARGFFKKGDVVIVL 511



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>KPYK_DEBHA (Q6BS75) Pyruvate kinase (EC 2.7.1.40) (PK)|
          Length = 504

 Score = 58.2 bits (139), Expect = 2e-08
 Identities = 36/121 (29%), Positives = 59/121 (48%)
 Frame = +1

Query: 55  PMSPLESLASSAVRTANKARATLIVVLTRGGTTAKLVAKYRPRVPILSVVVPVLTTDSFD 234
           P    E+ A ++V  A +  A  IVVL+  G T++LV+KY+P VP++ V           
Sbjct: 379 PTPTTETCAMASVSAAYEQDAKAIVVLSTSGFTSRLVSKYKPNVPVMMVT---------- 428

Query: 235 WTISSEGPARHSLIYRGLIPLLAEGSAKATDSESTEEILQAALKSAVKKQLCKAGDAVVV 414
               +   AR+  +YRG+ P + E        E  E  L+ A+  A+   + K GD++V 
Sbjct: 429 ---RNHRAARYCHLYRGVYPFVYEKKTVDNWQEDVENRLRWAVSEAIDLGIIKKGDSIVT 485

Query: 415 L 417
           +
Sbjct: 486 I 486



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>KPYK_ASHGO (Q759A9) Pyruvate kinase (EC 2.7.1.40) (PK)|
          Length = 501

 Score = 57.4 bits (137), Expect = 3e-08
 Identities = 37/141 (26%), Positives = 69/141 (48%), Gaps = 4/141 (2%)
 Frame = +1

Query: 49  PLPMSPLESLASSAVRTANKARATLIVVLTRGGTTAKLVAKYRPRVPILSVVVPVLTTDS 228
           P P    E++A++AV    + +A  IVVL+  G T +LV+KY+P VPI+ V         
Sbjct: 374 PKPTPTSETIAAAAVAATFEQKAKAIVVLSTSGDTTRLVSKYKPNVPIVMVT-------- 425

Query: 229 FDWTISSEGPARHSLIYRGLIPLLAEGSAKATDSESTEEILQAALKSAVKKQLCKAGDAV 408
                 +   AR+  ++RG+ P + E  A    ++  E  L   ++ + +  +   GD +
Sbjct: 426 -----RNPRAARYCHLHRGVFPFVYEQEAADEWTDDVEARLNFGVEKSKELGILSEGDTI 480

Query: 409 VVLH----RIGVASVIKICTV 459
           V +      +G ++ +++ TV
Sbjct: 481 VTIQGFASGVGHSNTLRVLTV 501



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>KPYK_TRIRE (P31865) Pyruvate kinase (EC 2.7.1.40) (PK)|
          Length = 538

 Score = 53.9 bits (128), Expect = 3e-07
 Identities = 40/125 (32%), Positives = 63/125 (50%), Gaps = 4/125 (3%)
 Frame = +1

Query: 55  PMSPLESLASSAVRTANKARATLIVVLTRGGTTAKLVAKYRPRVPILSVVVPVLTTDSFD 234
           P+S +ES A +AVR +    A  I+VL+  G +A+L++KYRP  PI  V     T     
Sbjct: 398 PVSTVESCAMAAVRASLDLGAGGIIVLSTSGDSARLLSKYRPVCPIFMVTRNPTT----- 452

Query: 235 WTISSEGPARHSLIYRGLIPLLAEGSAKATDS----ESTEEILQAALKSAVKKQLCKAGD 402
                   +R S +YRG+ P L        D+    E  ++ ++ A+  A++ +   AGD
Sbjct: 453 --------SRFSHLYRGVYPFLYPEQKPDFDTVNWQEDVDKRIKWAVTRAIELKTLTAGD 504

Query: 403 AVVVL 417
            VVV+
Sbjct: 505 TVVVV 509



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>KPYK2_YEAST (P52489) Pyruvate kinase 2 (EC 2.7.1.40) (PK 2)|
          Length = 506

 Score = 53.5 bits (127), Expect = 4e-07
 Identities = 42/143 (29%), Positives = 65/143 (45%), Gaps = 4/143 (2%)
 Frame = +1

Query: 43  AAPLPMSPLESLASSAVRTANKARATLIVVLTRGGTTAKLVAKYRPRVPILSVVVPVLTT 222
           A P P S  E++A++A     +     IVVL+  G TA+L++KYRP  PI+ V     T 
Sbjct: 373 ATPKPTSTTETVAAAATAAILEQDGKAIVVLSTTGNTARLLSKYRPSCPIILVTRHART- 431

Query: 223 DSFDWTISSEGPARHSLIYRGLIPLLAEGSAKATDSESTEEILQAALKSAVKKQLCKAGD 402
                       AR + +YRG+ P L E        E     L+  ++ A    +   GD
Sbjct: 432 ------------ARIAHLYRGVFPFLYEPKRLDDWGEDVHRRLKFGVEMARSFGMVDNGD 479

Query: 403 AVVVLH----RIGVASVIKICTV 459
            VV +      +G ++ ++I TV
Sbjct: 480 TVVSIQGFKGGVGHSNTLRISTV 502



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>KPYK_LEIME (Q27686) Pyruvate kinase (EC 2.7.1.40) (PK)|
          Length = 499

 Score = 53.5 bits (127), Expect = 4e-07
 Identities = 39/127 (30%), Positives = 60/127 (47%)
 Frame = +1

Query: 40  KAAPLPMSPLESLASSAVRTANKARATLIVVLTRGGTTAKLVAKYRPRVPILSVVVPVLT 219
           K   +PMS  E++  SAV + ++ +A  +VVL+  G  A+LVAKYRP  PI+ V   + T
Sbjct: 369 KLQHIPMSADEAVCGSAVNSVSETKAKAMVVLSNTGAGARLVAKYRPNCPIVCVTTRLQT 428

Query: 220 TDSFDWTISSEGPARHSLIYRGLIPLLAEGSAKATDSESTEEILQAALKSAVKKQLCKAG 399
                         R   I +G+  +  +   K    E  E  + A ++ A  K   + G
Sbjct: 429 -------------CRQLNITQGVESVFFDAD-KLGHDEGKEHRVAAGVEFAKSKGYVQTG 474

Query: 400 DAVVVLH 420
           D  VV+H
Sbjct: 475 DYCVVIH 481



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>KPYK_NEUCR (Q7RVA8) Pyruvate kinase (EC 2.7.1.40) (PK)|
          Length = 527

 Score = 53.5 bits (127), Expect = 4e-07
 Identities = 35/128 (27%), Positives = 64/128 (50%), Gaps = 4/128 (3%)
 Frame = +1

Query: 46  APLPMSPLESLASSAVRTANKARATLIVVLTRGGTTAKLVAKYRPRVPILSVVVPVLTTD 225
           A  P+S +ES A ++VR +    A  I+VL+  G +A+L++KYRP  PI+ +        
Sbjct: 385 AKRPVSIVESCAMASVRASLDLNAAAILVLSTSGESARLISKYRPVCPIIMIT------- 437

Query: 226 SFDWTISSEGPARHSLIYRGLIPLLAEGS----AKATDSESTEEILQAALKSAVKKQLCK 393
                  ++  +R++ +YRG+ P L   S    +K    E  +  ++  L   +  ++  
Sbjct: 438 ------RNDSASRYAHLYRGVYPFLFPESKPDFSKVNWQEDVDRRIKWGLSHGIGLKVLN 491

Query: 394 AGDAVVVL 417
            G+ VVV+
Sbjct: 492 EGETVVVV 499



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>KPYK_BACSU (P80885) Pyruvate kinase (EC 2.7.1.40) (PK) (Vegetative protein 17)|
           (VEG17)
          Length = 585

 Score = 53.1 bits (126), Expect = 6e-07
 Identities = 38/138 (27%), Positives = 69/138 (50%), Gaps = 4/138 (2%)
 Frame = +1

Query: 58  MSPLESLASSAVRTANKARATLIVVLTRGGTTAKLVAKYRPRVPILSVVVPVLTTDSFDW 237
           M+  +++  S   TA    A  IV  T  G TA+++AKYRP+ PI++V V          
Sbjct: 354 MTITDAIGQSVAHTAINLNAAAIVTPTESGHTARMIAKYRPQAPIVAVTV---------- 403

Query: 238 TISSEGPARHSLIYRGLIPLLAEGSAKATDSESTEEILQAALKSAVKKQLCKAGDAVVV- 414
              ++  +R   +  G   + AE    A+   ST+E+L+ A++ ++   + K GD +V+ 
Sbjct: 404 ---NDSISRKLALVSG---VFAESGQNAS---STDEMLEDAVQKSLNSGIVKHGDLIVIT 454

Query: 415 ---LHRIGVASVIKICTV 459
              +   G  +++K+ TV
Sbjct: 455 AGTVGESGTTNLMKVHTV 472



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>KPYK_ASPNG (Q12669) Pyruvate kinase (EC 2.7.1.40) (PK)|
          Length = 526

 Score = 52.8 bits (125), Expect = 8e-07
 Identities = 40/128 (31%), Positives = 60/128 (46%), Gaps = 6/128 (4%)
 Frame = +1

Query: 46  APLPMSPLESLASSAVRTANKARATLIVVLTRGGTTAKLVAKYRPRVPILSVVVPVLTTD 225
           AP P   +ES+A +AV  + +  A  IVVLT  G TA+ ++KYRP  PI+ V        
Sbjct: 386 APRPTDTVESIAMAAVSASLELNAGAIVVLTTSGKTARYLSKYRPVCPIVMVT------- 438

Query: 226 SFDWTISSEGPARHSLIYRGLIPLLAEGSAKATD------SESTEEILQAALKSAVKKQL 387
                  +   +R+S +YRG+ P L     K  D       E  +  L+  +  A+K  +
Sbjct: 439 ------RNPAASRYSHLYRGVWPFLF--PEKKPDFNVKVWQEDVDRRLKWGINHALKLGI 490

Query: 388 CKAGDAVV 411
              GD +V
Sbjct: 491 INKGDNIV 498



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>KPYK_BACPY (P51182) Pyruvate kinase (EC 2.7.1.40) (PK)|
          Length = 586

 Score = 52.4 bits (124), Expect = 1e-06
 Identities = 33/115 (28%), Positives = 58/115 (50%)
 Frame = +1

Query: 70  ESLASSAVRTANKARATLIVVLTRGGTTAKLVAKYRPRVPILSVVVPVLTTDSFDWTISS 249
           E++  +A  TA   +   ++  T  G TAK++AKYRP  P+++V              SS
Sbjct: 358 EAIGQAAAYTAINLKVKAVLAPTESGHTAKMIAKYRPGCPVIAVT-------------SS 404

Query: 250 EGPARHSLIYRGLIPLLAEGSAKATDSESTEEILQAALKSAVKKQLCKAGDAVVV 414
           E  +R   +  G+ P++ +       + S +EILQ +++ +VK Q    GD V++
Sbjct: 405 EMCSRKLSLIWGVYPIVGK------KASSIDEILQESVEESVKHQYVGHGDVVII 453



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>KPYK_EMENI (P22360) Pyruvate kinase (EC 2.7.1.40) (PK)|
          Length = 526

 Score = 52.4 bits (124), Expect = 1e-06
 Identities = 33/85 (38%), Positives = 46/85 (54%), Gaps = 2/85 (2%)
 Frame = +1

Query: 46  APLPMSPLESLASSAVRTANKARATLIVVLTRGGTTAKLVAKYRPRVPILSVVVPVLTTD 225
           AP P   +ES+A +AV  + +  A  IVVLT  G TA++++KYRP  PI+ V        
Sbjct: 386 APRPTDTVESIAMAAVSASLELNAGAIVVLTTSGNTARMISKYRPVCPIIMV-------- 437

Query: 226 SFDWTISSEGPA--RHSLIYRGLIP 294
                  S  PA  R+S +YRG+ P
Sbjct: 438 -------SRNPAATRYSHLYRGVWP 455



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>KPYK_LACLA (Q07637) Pyruvate kinase (EC 2.7.1.40) (PK)|
          Length = 502

 Score = 50.4 bits (119), Expect = 4e-06
 Identities = 36/123 (29%), Positives = 61/123 (49%)
 Frame = +1

Query: 70  ESLASSAVRTANKARATLIVVLTRGGTTAKLVAKYRPRVPILSVVVPVLTTDSFDWTISS 249
           E +A+S    A      LIV LT  G TA+L++K+RP   IL++        +FD     
Sbjct: 387 EVVAASVKNAAEAMDIKLIVALTESGNTARLISKHRPNADILAI--------TFD----- 433

Query: 250 EGPARHSLIYRGLIPLLAEGSAKATDSESTEEILQAALKSAVKKQLCKAGDAVVVLHRIG 429
           E   R  +I  G+IP + E         ST+++ + A K A+   L ++GD ++++  + 
Sbjct: 434 EKVERGLMINWGVIPTMTE------KPSSTDDMFEVAEKVALASGLVESGDNIIIVAGVP 487

Query: 430 VAS 438
           V +
Sbjct: 488 VGT 490



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>KPYK_SCHPO (Q10208) Pyruvate kinase (EC 2.7.1.40) (PK)|
          Length = 509

 Score = 50.4 bits (119), Expect = 4e-06
 Identities = 33/116 (28%), Positives = 56/116 (48%)
 Frame = +1

Query: 70  ESLASSAVRTANKARATLIVVLTRGGTTAKLVAKYRPRVPILSVVVPVLTTDSFDWTISS 249
           E+ A +A+  + ++ A  IVVL+  G TA+L +KYRP +PI+ V                
Sbjct: 388 ETTAVAAIGASIESDAKAIVVLSTSGNTARLCSKYRPSIPIVMVT-------------RC 434

Query: 250 EGPARHSLIYRGLIPLLAEGSAKATDSESTEEILQAALKSAVKKQLCKAGDAVVVL 417
              AR S + RG+ P++ E    +   +  +  +    + A K  + K GD ++VL
Sbjct: 435 PQRARQSHLNRGVYPVIYEKEPLSDWQKDVDARVAYGCQQAYKMNILKKGDKIIVL 490



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>KPYK1_SALTI (Q8Z6K2) Pyruvate kinase I (EC 2.7.1.40) (PK-1)|
          Length = 470

 Score = 50.1 bits (118), Expect = 5e-06
 Identities = 37/116 (31%), Positives = 60/116 (51%)
 Frame = +1

Query: 70  ESLASSAVRTANKARATLIVVLTRGGTTAKLVAKYRPRVPILSVVVPVLTTDSFDWTISS 249
           E++   AV TA K +A LIVV T+GG +A+ V KY P   IL+     LTT        +
Sbjct: 356 EAVCRGAVETAEKLKAPLIVVATQGGKSARAVRKYFPDATILA-----LTT--------N 402

Query: 250 EGPARHSLIYRGLIPLLAEGSAKATDSESTEEILQAALKSAVKKQLCKAGDAVVVL 417
           E  AR  ++ +G++  L +      +  ST++  +     A++  L + GD VV++
Sbjct: 403 EVTARQLVLSKGVVSQLVK------EINSTDDFYRLGKDVALQSGLAQKGDVVVMV 452



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>KPYK_CLOPE (Q46289) Pyruvate kinase (EC 2.7.1.40) (PK)|
          Length = 474

 Score = 49.7 bits (117), Expect = 6e-06
 Identities = 35/122 (28%), Positives = 62/122 (50%)
 Frame = +1

Query: 49  PLPMSPLESLASSAVRTANKARATLIVVLTRGGTTAKLVAKYRPRVPILSVVVPVLTTDS 228
           P P +  ++++ SA +TA+K     IV  T+ G+TAK+++KY+P  PI+++         
Sbjct: 352 PNPDAFADAISYSASKTASKFPTKAIVAATQTGSTAKILSKYKPSCPIIAIT-------- 403

Query: 229 FDWTISSEGPARHSLIYRGLIPLLAEGSAKATDSESTEEILQAALKSAVKKQLCKAGDAV 408
                  E   R   +  G+I      S K     ST+EI++ A K A + ++ + GD +
Sbjct: 404 -----PYEKVRRSLALNFGII------SKKCAYFNSTDEIIEEARKVAKEFEIAETGDNI 452

Query: 409 VV 414
           +V
Sbjct: 453 MV 454



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>KPYK1_ECOLI (P0AD61) Pyruvate kinase I (EC 2.7.1.40) (PK-1)|
          Length = 470

 Score = 49.7 bits (117), Expect = 6e-06
 Identities = 37/116 (31%), Positives = 59/116 (50%)
 Frame = +1

Query: 70  ESLASSAVRTANKARATLIVVLTRGGTTAKLVAKYRPRVPILSVVVPVLTTDSFDWTISS 249
           E++   AV TA K  A LIVV T+GG +A+ V KY P   IL+     LTT        +
Sbjct: 356 EAVCRGAVETAEKLDAPLIVVATQGGKSARAVRKYFPDATILA-----LTT--------N 402

Query: 250 EGPARHSLIYRGLIPLLAEGSAKATDSESTEEILQAALKSAVKKQLCKAGDAVVVL 417
           E  A   ++ +G++P L +      +  ST++  +   + A++  L   GD VV++
Sbjct: 403 EKTAHQLVLSKGVVPQLVK------EITSTDDFYRLGKELALQSGLAHKGDVVVMV 452



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>KPYK1_ECO57 (P0AD62) Pyruvate kinase I (EC 2.7.1.40) (PK-1)|
          Length = 470

 Score = 49.7 bits (117), Expect = 6e-06
 Identities = 37/116 (31%), Positives = 59/116 (50%)
 Frame = +1

Query: 70  ESLASSAVRTANKARATLIVVLTRGGTTAKLVAKYRPRVPILSVVVPVLTTDSFDWTISS 249
           E++   AV TA K  A LIVV T+GG +A+ V KY P   IL+     LTT        +
Sbjct: 356 EAVCRGAVETAEKLDAPLIVVATQGGKSARAVRKYFPDATILA-----LTT--------N 402

Query: 250 EGPARHSLIYRGLIPLLAEGSAKATDSESTEEILQAALKSAVKKQLCKAGDAVVVL 417
           E  A   ++ +G++P L +      +  ST++  +   + A++  L   GD VV++
Sbjct: 403 EKTAHQLVLSKGVVPQLVK------EITSTDDFYRLGKELALQSGLAHKGDVVVMV 452



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>KPYK1_SALTY (P77983) Pyruvate kinase I (EC 2.7.1.40) (PK-1)|
          Length = 470

 Score = 49.3 bits (116), Expect = 8e-06
 Identities = 37/116 (31%), Positives = 59/116 (50%)
 Frame = +1

Query: 70  ESLASSAVRTANKARATLIVVLTRGGTTAKLVAKYRPRVPILSVVVPVLTTDSFDWTISS 249
           E++   AV TA K  A LIVV T+GG +A+ V KY P   IL+     LTT        +
Sbjct: 356 EAVCRGAVETAEKLEAPLIVVATQGGKSARAVRKYFPDATILA-----LTT--------N 402

Query: 250 EGPARHSLIYRGLIPLLAEGSAKATDSESTEEILQAALKSAVKKQLCKAGDAVVVL 417
           E  AR  ++ +G++  L +      +  ST++  +     A++  L + GD VV++
Sbjct: 403 EVTARQLVLSKGVVSQLVK------EINSTDDFYRLGKDVALQSGLAQKGDVVVMV 452



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>KPYK_BACST (Q02499) Pyruvate kinase (EC 2.7.1.40) (PK)|
          Length = 587

 Score = 49.3 bits (116), Expect = 8e-06
 Identities = 34/115 (29%), Positives = 55/115 (47%)
 Frame = +1

Query: 70  ESLASSAVRTANKARATLIVVLTRGGTTAKLVAKYRPRVPILSVVVPVLTTDSFDWTISS 249
           +++  S   TA       IV  T  G T ++VAKYRP+ PI++V              S+
Sbjct: 359 DAIGQSVAHTALNLDVAAIVTPTVSGKTPQMVAKYRPKAPIIAVT-------------SN 405

Query: 250 EGPARHSLIYRGLIPLLAEGSAKATDSESTEEILQAALKSAVKKQLCKAGDAVVV 414
           E  +R   +  G+       + +A    +T+E+L  A+ +AV+  L K GD VV+
Sbjct: 406 EAVSRRLALVWGVY------TKEAPHVNTTDEMLDVAVDAAVRSGLVKHGDLVVI 454



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>KPYK_TRYBO (Q27788) Pyruvate kinase (EC 2.7.1.40) (PK)|
          Length = 498

 Score = 48.9 bits (115), Expect = 1e-05
 Identities = 38/122 (31%), Positives = 58/122 (47%)
 Frame = +1

Query: 55  PMSPLESLASSAVRTANKARATLIVVLTRGGTTAKLVAKYRPRVPILSVVVPVLTTDSFD 234
           P+ P E++ SSAV +  +  A  I+VLT  G +A +V+KYRP VPI      +  +   D
Sbjct: 373 PLIPEEAICSSAVNSIFELHAKAILVLTNTGRSAHMVSKYRPPVPI------ICASQELD 426

Query: 235 WTISSEGPARHSLIYRGLIPLLAEGSAKATDSESTEEILQAALKSAVKKQLCKAGDAVVV 414
                    R   I RG IP+  +      D +  E+ +  A+    +  + K GD VV 
Sbjct: 427 -------VCRLLSITRGTIPVYYDTEKLGPDYD-REKRVGLAIDVGKQMGVFKEGDVVVA 478

Query: 415 LH 420
           +H
Sbjct: 479 VH 480



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>KPYK_BACLI (P51181) Pyruvate kinase (EC 2.7.1.40) (PK)|
          Length = 585

 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 32/144 (22%), Positives = 66/144 (45%), Gaps = 4/144 (2%)
 Frame = +1

Query: 40  KAAPLPMSPLESLASSAVRTANKARATLIVVLTRGGTTAKLVAKYRPRVPILSVVVPVLT 219
           ++  + MS  +++  S   TA       IV  T  G TA++++KYRP+ PI++V V    
Sbjct: 348 RSKQVSMSITDAIGQSVAHTAINLDVNAIVTPTESGHTARMISKYRPQAPIVAVTV---- 403

Query: 220 TDSFDWTISSEGPARHSLIYRGLIPLLAEGSAKATDSESTEEILQAALKSAVKKQLCKAG 399
                          +  + R L  +    +    +  ST+E+L+ A++ ++   + + G
Sbjct: 404 ---------------NDAVSRKLSLVFGVFATSGQNHSSTDEMLEKAVQKSLDTGIVRHG 448

Query: 400 DAVVV----LHRIGVASVIKICTV 459
           D +V+    +   G  +++K+  V
Sbjct: 449 DLIVITAGAVGEAGTTNLMKVYVV 472



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>KPYK_AGABI (O94122) Pyruvate kinase (EC 2.7.1.40) (PK)|
          Length = 532

 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 35/142 (24%), Positives = 67/142 (47%), Gaps = 7/142 (4%)
 Frame = +1

Query: 55  PMSPLESLASSAVRTANKARATLIVVLTRGGTTAKLVAKYRPRVPILSVVVPVLTTDSFD 234
           P    E++A +AV  A +  A  ++VL+  G TA+LV+KYRP++PI++V           
Sbjct: 389 PTETAETVAIAAVAAAAEQDAKALLVLSTSGETARLVSKYRPKIPIITVT---------- 438

Query: 235 WTISSEGPARHSLIYRGLIPLL---AEGSAKATDSESTEEILQAALKSAVKKQLCKAGDA 405
               +E  AR   ++RG  P       G          +  ++  L++A+   + + G +
Sbjct: 439 ---RNEQTARQIHLHRGCYPFWYPEPRGVQNHQWQTDVDNRIRFGLRNALALNVIQPGAS 495

Query: 406 VVVLH----RIGVASVIKICTV 459
           ++ +      +G  + ++I TV
Sbjct: 496 IIAVQGWKGGLGHTNTLRILTV 517



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>KPYK_LACDE (P34038) Pyruvate kinase (EC 2.7.1.40) (PK)|
          Length = 589

 Score = 47.4 bits (111), Expect = 3e-05
 Identities = 35/117 (29%), Positives = 60/117 (51%), Gaps = 1/117 (0%)
 Frame = +1

Query: 70  ESLASSAVRTANKARATLIVVLTRGGTTAKLVAKYRPRVPILSVVVPVLTTDSFDWTISS 249
           E++  S VRTA +     I+  T  G TA++++KYRP   I+++        +FD  I  
Sbjct: 361 EAIGESVVRTAQELGVKTIIAATSSGYTARMISKYRPDATIVAL--------TFDEKI-- 410

Query: 250 EGPARHSL-IYRGLIPLLAEGSAKATDSESTEEILQAALKSAVKKQLCKAGDAVVVL 417
               +HSL I  G+ P+LA+         +T+E+ + A + A +    K GD V+++
Sbjct: 411 ----QHSLGIVWGVEPVLAK------KPSNTDEMFEEAARVAKEHGFVKDGDLVIIV 457



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>KPYK2_SYNY3 (P73534) Pyruvate kinase 2 (EC 2.7.1.40) (PK 2)|
          Length = 591

 Score = 46.2 bits (108), Expect = 7e-05
 Identities = 34/114 (29%), Positives = 55/114 (48%)
 Frame = +1

Query: 73  SLASSAVRTANKARATLIVVLTRGGTTAKLVAKYRPRVPILSVVVPVLTTDSFDWTISSE 252
           +++S+  + A    A  I+ LT+ G+TA+ V+K+RP+ PIL+V   V             
Sbjct: 362 AISSAVSQIAETLNAAAIMSLTKTGSTARHVSKFRPKTPILAVTPHV------------- 408

Query: 253 GPARHSLIYRGLIPLLAEGSAKATDSESTEEILQAALKSAVKKQLCKAGDAVVV 414
             +R   +  G+ PLL        D  ST +  QAA+  A +    + GD VV+
Sbjct: 409 DVSRQLQLVWGVKPLL------VLDLPSTSQTFQAAINVAQENHFLRDGDLVVM 456



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>KPYK_CLOAB (O08309) Pyruvate kinase (EC 2.7.1.40) (PK)|
          Length = 473

 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 31/121 (25%), Positives = 61/121 (50%), Gaps = 5/121 (4%)
 Frame = +1

Query: 115 ATLIVVLTRGGTTAKLVAKYRPRVPILSVVVPVLTTDSFDWTISSEGPARHSLIYRGLIP 294
           A+ I+  T+ G+TA+ V+KYRP+ P+++V               SE  AR   +  G+ P
Sbjct: 372 ASAIITATQTGSTARTVSKYRPKAPVIAVT-------------PSEKVARKLAMSWGVHP 418

Query: 295 LLAEGSAKATDSESTEEILQAALKSAVKKQLCKAGDAVVVLHRI-----GVASVIKICTV 459
           ++++         ST+E++  ++  A++    + GD VVV   +     G  +++K+  V
Sbjct: 419 IISDKFG------STDELISTSVDKALEAGYVQKGDLVVVAAGVPTNVSGTTNMLKVQVV 472

Query: 460 Q 462
           +
Sbjct: 473 E 473



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>KPYK_CHLMU (Q9PK61) Pyruvate kinase (EC 2.7.1.40) (PK)|
          Length = 481

 Score = 43.5 bits (101), Expect = 5e-04
 Identities = 27/79 (34%), Positives = 45/79 (56%), Gaps = 16/79 (20%)
 Frame = +1

Query: 40  KAAPLPMSP-LESLASSAVRTANKARATLIVVLTRGGTTAKLVAKYRPRVPILSV----- 201
           K + L +SP LE++ +S ++ A KA A  I+V T+ G +   ++KYRP +PI++V     
Sbjct: 349 KNSALKVSPYLEAIGASGIQIAEKASAKAIIVYTQTGGSPMFLSKYRPYLPIIAVTPNRN 408

Query: 202 ----------VVPVLTTDS 228
                     V P+LT++S
Sbjct: 409 VYYRLAVEWGVYPMLTSES 427



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>KPYK1_AGRVI (P70789) Pyruvate kinase (EC 2.7.1.40) (PK)|
          Length = 474

 Score = 42.0 bits (97), Expect = 0.001
 Identities = 32/119 (26%), Positives = 59/119 (49%)
 Frame = +1

Query: 61  SPLESLASSAVRTANKARATLIVVLTRGGTTAKLVAKYRPRVPILSVVVPVLTTDSFDWT 240
           +P  ++A++A   A   +A +IV  T  GTTA  +++ RP +PIL++             
Sbjct: 355 TPPHAVATAAADVALALKAPVIVAFTVSGTTASRISRARPPLPILALT------------ 402

Query: 241 ISSEGPARHSLIYRGLIPLLAEGSAKATDSESTEEILQAALKSAVKKQLCKAGDAVVVL 417
             SE  AR   +  G++ LL      +   ++ E+ +  A ++AV+  L +  D +VV+
Sbjct: 403 -PSEQTARQLGLMWGVVSLL------SPTVDTYEQSVDRATQAAVQTGLAEKSDQIVVV 454



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>KPYK_CHLTR (P94685) Pyruvate kinase (EC 2.7.1.40) (PK)|
          Length = 485

 Score = 42.0 bits (97), Expect = 0.001
 Identities = 22/55 (40%), Positives = 36/55 (65%), Gaps = 1/55 (1%)
 Frame = +1

Query: 40  KAAPLPMSP-LESLASSAVRTANKARATLIVVLTRGGTTAKLVAKYRPRVPILSV 201
           K + L +SP LE++  S ++ A KA A  I+V T+ G +   ++KYRP +PI++V
Sbjct: 349 KNSALKVSPYLEAIGFSGIQIAEKASAKAIIVYTQTGGSPMFLSKYRPYLPIIAV 403



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>KPYK_THEAC (P32044) Pyruvate kinase (EC 2.7.1.40) (PK)|
          Length = 544

 Score = 39.7 bits (91), Expect = 0.007
 Identities = 31/111 (27%), Positives = 56/111 (50%), Gaps = 1/111 (0%)
 Frame = +1

Query: 73  SLASSAVRTANKARATLIVVLTRGGTTAKLVAKYRPRVPILSVVVPVLTTDSFDWTISSE 252
           S+A +A   ++  ++  IV LT  G+T ++++  RP+  + +  V             SE
Sbjct: 337 SVARAAKILSDDIKSDGIVALTHTGSTVRMISSLRPKAMVYAATV-------------SE 383

Query: 253 GPARHSLIYRGLIPLLAEGSAK-ATDSESTEEILQAALKSAVKKQLCKAGD 402
             AR   IY G++PL  EG+A+  + SE  E I+++   +   K +  +GD
Sbjct: 384 SLARKLNIYFGVLPLHMEGNAEDLSFSEIMEYIVRSGRFADGSKLVMTSGD 434



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>KPYK_CHLPN (Q9Z984) Pyruvate kinase (EC 2.7.1.40) (PK)|
          Length = 484

 Score = 37.7 bits (86), Expect = 0.025
 Identities = 17/51 (33%), Positives = 33/51 (64%), Gaps = 1/51 (1%)
 Frame = +1

Query: 52  LPMSP-LESLASSAVRTANKARATLIVVLTRGGTTAKLVAKYRPRVPILSV 201
           L +SP L ++  + ++ A +A A  ++V T  G++   ++KYRP+ PI++V
Sbjct: 353 LQVSPYLSAIGLAGIQIAERADAKALIVYTESGSSPMFLSKYRPKFPIIAV 403



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>KPYK2_AGRVI (Q44473) Pyruvate kinase (EC 2.7.1.40) (PK)|
          Length = 482

 Score = 36.6 bits (83), Expect = 0.056
 Identities = 28/119 (23%), Positives = 55/119 (46%)
 Frame = +1

Query: 61  SPLESLASSAVRTANKARATLIVVLTRGGTTAKLVAKYRPRVPILSVVVPVLTTDSFDWT 240
           SP  ++A++A   A    + ++V  T  GTTA  +++ RP +PIL++             
Sbjct: 355 SPPHAVATAAANVAVALGSPVVVAYTSSGTTAARISRARPALPILALT------------ 402

Query: 241 ISSEGPARHSLIYRGLIPLLAEGSAKATDSESTEEILQAALKSAVKKQLCKAGDAVVVL 417
             SE  AR   ++ G++        ++ D  + E  L  A ++  + +L    D +V++
Sbjct: 403 -PSEQVARRLNMFWGVV------GVRSQDVHTYEASLIHAQQAVQEAKLASPSDHIVIV 454



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>CO3A1_HUMAN (P02461) Collagen alpha-1(III) chain precursor|
          Length = 1466

 Score = 31.6 bits (70), Expect(2) = 0.19
 Identities = 34/120 (28%), Positives = 42/120 (35%), Gaps = 2/120 (1%)
 Frame = +3

Query: 3    PGTTTPSSRXXDQGRTPPDEPARVPRLLGGADRQQGQGHSDCRPDPWRHHGQAGCQVPA- 179
            PG   P+ +  D+G + P  PA  P   G       QG       P    G+ G +  A 
Sbjct: 1052 PGPVGPAGKSGDRGESGPAGPAGAPGPAGSRGAPGPQG-------PRGDKGETGERGAAG 1104

Query: 180  -QGSDPFGGRPGAXXXXXXXXXXXXGPCQAQPDLQRPDPAPCRRLRQGHRLRVDGGDPPG 356
             +G   F G PGA            GP   Q  +  P PA       G R  V    PPG
Sbjct: 1105 IKGHRGFPGNPGA--------PGSPGPAGQQGAIGSPGPA-------GPRGPVGPSGPPG 1149



 Score = 21.9 bits (45), Expect(2) = 0.19
 Identities = 7/10 (70%), Positives = 7/10 (70%)
 Frame = +2

Query: 485  PEHPGPCCRG 514
            P  PGPCC G
Sbjct: 1190 PGAPGPCCGG 1199



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>HLDE_SALTY (Q7CPR9) Bifunctional protein hldE [Includes: D-beta-D-heptose|
           7-phosphate kinase (EC 2.7.1.-) (D-beta-D-heptose
           7-phosphotransferase); D-beta-D-heptose 1-phosphate
           adenosyltransferase (EC 2.7.7.-)]
          Length = 477

 Score = 34.7 bits (78), Expect = 0.21
 Identities = 25/90 (27%), Positives = 42/90 (46%), Gaps = 2/90 (2%)
 Frame = +1

Query: 85  SAVRTANKARATLIVVLTRGGTTAKLVAKYRPRVPILSVVVPVLTTDSFDWTISSEGPAR 264
           S +  A K    LIV +    +T +L  + RP  P+   ++ +   +S DW +S E    
Sbjct: 358 SYLANARKLGDRLIVAVNSDASTKRLKGESRPVNPLEQRMIVLGALESVDWVVSFEEDTP 417

Query: 265 HSLIYRGLIP--LLAEGSAKATDSESTEEI 348
             LI  G++P  L+  G  K  +   +EE+
Sbjct: 418 QRLI-AGILPDLLVKGGDYKPEEIAGSEEV 446



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>HLDE_SALTI (Q8XEW9) Bifunctional protein hldE [Includes: D-beta-D-heptose|
           7-phosphate kinase (EC 2.7.1.-) (D-beta-D-heptose
           7-phosphotransferase); D-beta-D-heptose 1-phosphate
           adenosyltransferase (EC 2.7.7.-)]
          Length = 477

 Score = 34.7 bits (78), Expect = 0.21
 Identities = 25/90 (27%), Positives = 42/90 (46%), Gaps = 2/90 (2%)
 Frame = +1

Query: 85  SAVRTANKARATLIVVLTRGGTTAKLVAKYRPRVPILSVVVPVLTTDSFDWTISSEGPAR 264
           S +  A K    LIV +    +T +L  + RP  P+   ++ +   +S DW +S E    
Sbjct: 358 SYLANARKLGDRLIVAVNSDASTKRLKGESRPVNPLEQRMIVLGALESVDWVVSFEEDTP 417

Query: 265 HSLIYRGLIP--LLAEGSAKATDSESTEEI 348
             LI  G++P  L+  G  K  +   +EE+
Sbjct: 418 QRLI-AGILPDLLVKGGDYKPEEIAGSEEV 446



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>COL2_CAEEL (P17656) Cuticle collagen 2 precursor|
          Length = 301

 Score = 33.5 bits (75), Expect = 0.48
 Identities = 29/96 (30%), Positives = 36/96 (37%), Gaps = 1/96 (1%)
 Frame = -3

Query: 321 GLGGAFGKERDQASVDQAVPGRALGANGPVERVSRQHRDDHRKDRNPGPV-LGNQLGRGA 145
           G  GA G   +  + +Q  PG   G  GP         D       PGP       G   
Sbjct: 198 GAPGAPGGPGEPGASEQGGPGEP-GPAGPPGPAGPAGNDGAPGTGGPGPAGPKGPPGAAG 256

Query: 144 ATGQDDNQSGPGLVGGPHRRGGEGLERAHREGCGLD 37
           A G D N  GPG  G   + GGEG +    + C +D
Sbjct: 257 APGADGNPGGPGTAG---KPGGEGEKGICPKYCAID 289



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>VE1_HPV10 (P36720) Replication protein E1 (EC 3.6.1.-) (ATP-dependent|
           helicase E1)
          Length = 681

 Score = 33.1 bits (74), Expect = 0.62
 Identities = 23/81 (28%), Positives = 37/81 (45%)
 Frame = -3

Query: 243 NGPVERVSRQHRDDHRKDRNPGPVLGNQLGRGAATGQDDNQSGPGLVGGPHRRGGEGLER 64
           +GP +        D R+D + G V+ + L  G   G+ +N  G G   G H  G +  ER
Sbjct: 147 SGPKQVQGSSETQDGRQDDDEGSVVQSTLDTGNQNGRQNNDEGSGRNVGEH--GSQEEER 204

Query: 63  AHREGCGLDHXXLKTASLXQG 1
           A  +G   +   L++ S  +G
Sbjct: 205 AGGDG---EESDLQSTSTGKG 222



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>CO1A2_RABIT (Q28668) Collagen alpha-2(I) chain precursor (Fragment)|
          Length = 526

 Score = 32.7 bits (73), Expect = 0.81
 Identities = 24/85 (28%), Positives = 32/85 (37%), Gaps = 2/85 (2%)
 Frame = -3

Query: 321 GLGGAFGKERDQASVDQAVPGRALGANGPVERVSRQHRDDHRKDRNPGPVLGNQLGRGAA 142
           GL G  G+  DQ +     P    G  GP     +  R  H     P  + G+Q  +G A
Sbjct: 190 GLPGLAGQHGDQGAPGAVGPAGPRGPAGPTGPAGKDGRSGHPGTVGPAGLRGSQGSQGPA 249

Query: 141 --TGQDDNQSGPGLVGGPHRRGGEG 73
              G       PG  GG +  G +G
Sbjct: 250 GPPGPPGPPGPPGASGGGYDFGYDG 274



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>CO6A2_MOUSE (Q02788) Collagen alpha-2(VI) chain precursor|
          Length = 1029

 Score = 32.7 bits (73), Expect = 0.81
 Identities = 26/86 (30%), Positives = 40/86 (46%), Gaps = 3/86 (3%)
 Frame = -3

Query: 321 GLGGAFGKERDQ-ASVDQAVPGRALGANGPVERVSRQHRDDHRKDRNPGPVLGNQLGRG- 148
           G  G+ G+  DQ A  D   PGR      P ++ S+ ++ ++    +PG V G + G G 
Sbjct: 368 GEAGSPGERGDQGAKGDSGRPGRRGPPGDPGDKGSKGYQGNNGAPGSPG-VKGGKGGPGP 426

Query: 147 -AATGQDDNQSGPGLVGGPHRRGGEG 73
               G+   +  PG  GGP   G +G
Sbjct: 427 RGPKGEPGRRGDPGTKGGPGSDGPKG 452



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>ATX7_HUMAN (O15265) Ataxin-7 (Spinocerebellar ataxia type 7 protein)|
          Length = 892

 Score = 32.3 bits (72), Expect = 1.1
 Identities = 34/116 (29%), Positives = 41/116 (35%), Gaps = 4/116 (3%)
 Frame = +3

Query: 21  SSRXXDQGRTPPDEPARVPRLLGGAD----RQQGQGHSDCRPDPWRHHGQAGCQVPAQGS 188
           S R  D  R    EP R     GGA     RQQ Q     +P P +   Q     P + +
Sbjct: 2   SERAADDVR---GEPRRAAAAAGGAAAAAARQQQQQQQQQQPPPPQPQRQQHPPPPPRRT 58

Query: 189 DPFGGRPGAXXXXXXXXXXXXGPCQAQPDLQRPDPAPCRRLRQGHRLRVDGGDPPG 356
            P  G PGA                A    +RP P+P   L Q   L V+    PG
Sbjct: 59  RPEDGGPGAASTSAA--------AMATVGERRPLPSPEVMLGQSWNLWVEASKLPG 106



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>HYDL_STRCO (P42534) Putative polyketide hydroxylase (EC 1.14.13.-) (WhiE ORF|
           VIII)
          Length = 627

 Score = 32.3 bits (72), Expect = 1.1
 Identities = 16/36 (44%), Positives = 17/36 (47%)
 Frame = -3

Query: 180 GPVLGNQLGRGAATGQDDNQSGPGLVGGPHRRGGEG 73
           GP  G   G G  TG      GPG +GGP   GG G
Sbjct: 399 GPGAGTPGGAGRGTGGPGGPGGPGGLGGPGGPGGTG 434



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>IF2_CORDI (Q6NGN2) Translation initiation factor IF-2|
          Length = 953

 Score = 31.6 bits (70), Expect = 1.8
 Identities = 28/110 (25%), Positives = 36/110 (32%), Gaps = 14/110 (12%)
 Frame = +3

Query: 9   TTTPSSRXXDQGRTPPDEPARVPRLL--------------GGADRQQGQGHSDCRPDPWR 146
           T TP S    Q +  P    R PR+               GG +R          P P  
Sbjct: 151 TATPGSMPRPQAKPAPKPGGRAPRVANNPFSSGPRPAPRPGGGNRSGNAPRPGGGPRPGG 210

Query: 147 HHGQAGCQVPAQGSDPFGGRPGAXXXXXXXXXXXXGPCQAQPDLQRPDPA 296
           +  Q G   PA+ +   GGR G             G  + Q   +RP PA
Sbjct: 211 NRPQGGQGGPAERAPRPGGRGGQPRPQGGSRSQQSGGQERQGGGRRPSPA 260



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>BCOR_HUMAN (Q6W2J9) BCoR protein (BCL-6 corepressor)|
          Length = 1755

 Score = 31.6 bits (70), Expect = 1.8
 Identities = 16/45 (35%), Positives = 24/45 (53%)
 Frame = -1

Query: 479 MPGGHHWTVQILMTEATPMRCRTTTASPALQSCFFTADLSAAWRI 345
           +P  H+    I  + A+PMR  T +ASPA+      AD S  W++
Sbjct: 247 LPPPHYVGPHIPSSLASPMRLSTPSASPAIPPLVHCADKSLPWKM 291



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>LAMC2_HUMAN (Q13753) Laminin gamma-2 chain precursor (Laminin 5 gamma 2|
           subunit) (Kalinin/nicein/epiligrin 100 kDa subunit)
           (Laminin B2t chain) (Cell-scattering factor 140 kDa
           subunit) (CSF 140 kDa subunit) (Large adhesive scatter
           factor 140 kDa subunit)
          Length = 1193

 Score = 31.2 bits (69), Expect = 2.4
 Identities = 17/43 (39%), Positives = 22/43 (51%), Gaps = 2/43 (4%)
 Frame = +3

Query: 252 GPCQAQPDLQRPDPAP--CRRLRQGHRLRVDGGDPPGCAQVGC 374
           GPC A   + +P      C R R G+   +DGG+P GC Q  C
Sbjct: 148 GPCDAGRCVCKPAVTGERCDRCRSGY-YNLDGGNPEGCTQCFC 189



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>HLDE_ECOLI (P76658) Bifunctional protein hldE [Includes: D-beta-D-heptose|
           7-phosphate kinase (EC 2.7.1.-) (D-beta-D-heptose
           7-phosphotransferase); D-beta-D-heptose 1-phosphate
           adenosyltransferase (EC 2.7.7.-)]
          Length = 477

 Score = 31.2 bits (69), Expect = 2.4
 Identities = 23/90 (25%), Positives = 41/90 (45%), Gaps = 2/90 (2%)
 Frame = +1

Query: 85  SAVRTANKARATLIVVLTRGGTTAKLVAKYRPRVPILSVVVPVLTTDSFDWTISSEGPAR 264
           S +  A K    LIV +    +T +L    RP  P+   ++ +   ++ DW +S E    
Sbjct: 358 SYLANARKLGDRLIVAVNSDASTKRLKGDSRPVNPLEQRMIVLGALEAVDWVVSFEEDTP 417

Query: 265 HSLIYRGLIP--LLAEGSAKATDSESTEEI 348
             LI  G++P  L+  G  K  +   ++E+
Sbjct: 418 QRLI-AGILPDLLVKGGDYKPEEIAGSKEV 446



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>HLDE_ECOL6 (Q8FDH5) Bifunctional protein hldE [Includes: D-beta-D-heptose|
           7-phosphate kinase (EC 2.7.1.-) (D-beta-D-heptose
           7-phosphotransferase); D-beta-D-heptose 1-phosphate
           adenosyltransferase (EC 2.7.7.-)]
          Length = 477

 Score = 31.2 bits (69), Expect = 2.4
 Identities = 23/90 (25%), Positives = 41/90 (45%), Gaps = 2/90 (2%)
 Frame = +1

Query: 85  SAVRTANKARATLIVVLTRGGTTAKLVAKYRPRVPILSVVVPVLTTDSFDWTISSEGPAR 264
           S +  A K    LIV +    +T +L    RP  P+   ++ +   ++ DW +S E    
Sbjct: 358 SYLANARKLGDRLIVAVNSDASTKRLKGDSRPVNPLEQRMIVLGALEAVDWVVSFEEDTP 417

Query: 265 HSLIYRGLIP--LLAEGSAKATDSESTEEI 348
             LI  G++P  L+  G  K  +   ++E+
Sbjct: 418 QRLI-AGILPDLLVKGGDYKPEEIAGSKEV 446



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>HLDE_ECO57 (Q7AAQ7) Bifunctional protein hldE [Includes: D-beta-D-heptose|
           7-phosphate kinase (EC 2.7.1.-) (D-beta-D-heptose
           7-phosphotransferase); D-beta-D-heptose 1-phosphate
           adenosyltransferase (EC 2.7.7.-)]
          Length = 477

 Score = 31.2 bits (69), Expect = 2.4
 Identities = 23/90 (25%), Positives = 41/90 (45%), Gaps = 2/90 (2%)
 Frame = +1

Query: 85  SAVRTANKARATLIVVLTRGGTTAKLVAKYRPRVPILSVVVPVLTTDSFDWTISSEGPAR 264
           S +  A K    LIV +    +T +L    RP  P+   ++ +   ++ DW +S E    
Sbjct: 358 SYLANARKLGDRLIVAVNSDASTKRLKGDSRPVNPLEQRMIVLGALEAVDWVVSFEEDTP 417

Query: 265 HSLIYRGLIP--LLAEGSAKATDSESTEEI 348
             LI  G++P  L+  G  K  +   ++E+
Sbjct: 418 QRLI-AGILPDLLVKGGDYKPEEIAGSKEV 446



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>5E5_RAT (Q63003) 5E5 antigen|
          Length = 825

 Score = 31.2 bits (69), Expect = 2.4
 Identities = 28/96 (29%), Positives = 32/96 (33%)
 Frame = -3

Query: 327 VCGLGGAFGKERDQASVDQAVPGRALGANGPVERVSRQHRDDHRKDRNPGPVLGNQLGRG 148
           V GLG   G++R  A   Q +P  A         V             PGP      GRG
Sbjct: 520 VLGLGTTSGEQR--ADQSQTLPALAGAPTAHAHAVP-----------GPGPAAATLGGRG 566

Query: 147 AATGQDDNQSGPGLVGGPHRRGGEGLERAHREGCGL 40
                   + G G       RGG G  R  R G GL
Sbjct: 567 RRGSWRGGRRGGGAGASGGGRGGRGRGRGGRRGSGL 602



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>CO1A1_CHICK (P02457) Collagen alpha-1(I) chain precursor|
          Length = 1453

 Score = 31.2 bits (69), Expect = 2.4
 Identities = 25/71 (35%), Positives = 28/71 (39%), Gaps = 1/71 (1%)
 Frame = -3

Query: 276 DQAVPGRALGANGPV-ERVSRQHRDDHRKDRNPGPVLGNQLGRGAATGQDDNQSGPGLVG 100
           +Q VPG A GA GP   R  R    +      PGP      G   A G D  +   G  G
Sbjct: 649 EQGVPGNA-GAPGPAGARGERGFPGERGVQGPPGPQ--GPRGANGAPGNDGAKGDAGAPG 705

Query: 99  GPHRRGGEGLE 67
            P   G  GLE
Sbjct: 706 APGNEGPPGLE 716



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>CO1A1_BOVIN (P02453) Collagen alpha-1(I) chain (Fragments)|
          Length = 779

 Score = 30.8 bits (68), Expect = 3.1
 Identities = 24/71 (33%), Positives = 30/71 (42%), Gaps = 1/71 (1%)
 Frame = -3

Query: 276 DQAVPGRALGANGPV-ERVSRQHRDDHRKDRNPGPVLGNQLGRGAATGQDDNQSGPGLVG 100
           +Q VPG  LGA GP   R  R    +   +  PGP      G   A G D  +   G  G
Sbjct: 225 EQGVPGD-LGAPGPSGARGERGFPGERGVEGPPGPA--GPRGANGAPGNDGAKGDAGAPG 281

Query: 99  GPHRRGGEGLE 67
            P  +G  GL+
Sbjct: 282 APGSQGAPGLQ 292



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>YNU8_YEAST (P40159) Protein YNL208W|
          Length = 199

 Score = 30.8 bits (68), Expect = 3.1
 Identities = 20/60 (33%), Positives = 25/60 (41%), Gaps = 6/60 (10%)
 Frame = -3

Query: 204 DHRKDRNPGPVLGNQLGRGAATG------QDDNQSGPGLVGGPHRRGGEGLERAHREGCG 43
           D RK+       GN    GA  G      + DN +  G  GGP   GG+G  R   +G G
Sbjct: 87  DERKEHKQQEQYGNSNFGGAPQGGHNNHHRQDNNNNNGGFGGPGGPGGQGFGRQGPQGFG 146



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>IE63_HHV2H (P28276) Transcriptional regulator IE63 (VMW63) (ICP27)|
          Length = 512

 Score = 30.8 bits (68), Expect = 3.1
 Identities = 28/83 (33%), Positives = 33/83 (39%)
 Frame = -3

Query: 315 GGAFGKERDQASVDQAVPGRALGANGPVERVSRQHRDDHRKDRNPGPVLGNQLGRGAATG 136
           GG  G+ R +       PG A     P  RVSR                 NQ GR  A+ 
Sbjct: 139 GGRRGRRRGRGRYG---PGGADSTPKPRRRVSRNAH--------------NQGGRHPASA 181

Query: 135 QDDNQSGPGLVGGPHRRGGEGLE 67
           + D   GPG   G  RRGGE L+
Sbjct: 182 RTD---GPGATHGEARRGGEQLD 201



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>ATS1_HUMAN (Q9UHI8) ADAMTS-1 precursor (EC 3.4.24.-) (A disintegrin and|
           metalloproteinase with thrombospondin motifs 1) (ADAM-TS
           1) (ADAM-TS1) (METH-1)
          Length = 967

 Score = 30.8 bits (68), Expect = 3.1
 Identities = 17/41 (41%), Positives = 20/41 (48%)
 Frame = -2

Query: 400 LQPCRAASSQPT*AQPGGSPPSTLSLWPWRSLRQGAGSGLC 278
           +QP  AAS +   A PG  PP+ L     R  RQG   G C
Sbjct: 158 IQPLPAASERLATAAPGEKPPAPLQFHLLRRNRQGDVGGTC 198



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>HLDE_YERPE (Q8ZI60) Bifunctional protein hldE [Includes: D-beta-D-heptose|
           7-phosphate kinase (EC 2.7.1.-) (D-beta-D-heptose
           7-phosphotransferase); D-beta-D-heptose 1-phosphate
           adenosyltransferase (EC 2.7.7.-)]
          Length = 476

 Score = 30.4 bits (67), Expect = 4.0
 Identities = 25/92 (27%), Positives = 40/92 (43%), Gaps = 1/92 (1%)
 Frame = +1

Query: 85  SAVRTANKARATLIVVLTRGGTTAKLVAKYRPRVPILSVVVPVLTTDSFDWTISSEGPAR 264
           S +  A K    LIV +    +T +L  + RP  P+   +V +   ++ DW +  E    
Sbjct: 358 SYLANARKLGDRLIVAVNSDASTKRLKGEKRPVNPLEQRMVVLGALEAVDWVVPFEEDTP 417

Query: 265 HSLIYRGLIPLLAE-GSAKATDSESTEEILQA 357
             LI   L  LL + G  K  +   +EE+  A
Sbjct: 418 QRLIADILPDLLVKGGDYKPHEIAGSEEVWAA 449



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>HLDE_SHIFL (Q7UBI8) Bifunctional protein hldE [Includes: D-beta-D-heptose|
           7-phosphate kinase (EC 2.7.1.-) (D-beta-D-heptose
           7-phosphotransferase); D-beta-D-heptose 1-phosphate
           adenosyltransferase (EC 2.7.7.-)]
          Length = 477

 Score = 30.4 bits (67), Expect = 4.0
 Identities = 22/85 (25%), Positives = 39/85 (45%), Gaps = 2/85 (2%)
 Frame = +1

Query: 100 ANKARATLIVVLTRGGTTAKLVAKYRPRVPILSVVVPVLTTDSFDWTISSEGPARHSLIY 279
           A K    LIV +    +T +L    RP  P+   ++ +   ++ DW +S E      LI 
Sbjct: 363 ARKLGDRLIVAVNSDASTKRLKGDSRPVNPLEQRMIVLGALEAVDWVVSFEEDTPQRLI- 421

Query: 280 RGLIP--LLAEGSAKATDSESTEEI 348
            G++P  L+  G  K  +   ++E+
Sbjct: 422 AGILPDLLVKGGDYKPEEIAGSKEV 446



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>COHA1_CHICK (Q90584) Collagen alpha-1(XVII) chain (Bullous pemphigoid antigen|
           2) (180 kDa bullous pemphigoid antigen 2) (Fragment)
          Length = 1146

 Score = 30.4 bits (67), Expect = 4.0
 Identities = 28/93 (30%), Positives = 33/93 (35%), Gaps = 10/93 (10%)
 Frame = -3

Query: 321 GLGGAFGKERDQASVDQAVPGRALGANGPVERVSRQHRDDHRKDRN----------PGPV 172
           G  GA G   +Q S     P    GA GP  +  R  +   R +            PGP 
Sbjct: 296 GEKGAHGMTGEQGSRGIPGPPGEPGAKGPAGQAGRDGQPGERGEPGLMGIPGARGPPGP- 354

Query: 171 LGNQLGRGAATGQDDNQSGPGLVGGPHRRGGEG 73
                G    TG    Q  PGL G P R G +G
Sbjct: 355 -SGDTGEPGLTGP---QGPPGLPGNPGRPGAKG 383



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>CO1A1_RAT (P02454) Collagen alpha-1(I) chain precursor|
          Length = 1453

 Score = 30.4 bits (67), Expect = 4.0
 Identities = 24/71 (33%), Positives = 29/71 (40%), Gaps = 1/71 (1%)
 Frame = -3

Query: 276 DQAVPGRALGANGPV-ERVSRQHRDDHRKDRNPGPVLGNQLGRGAATGQDDNQSGPGLVG 100
           +Q VPG  LGA GP   R  R    +      PGP      G   A G D  +   G  G
Sbjct: 649 EQGVPGD-LGAPGPSGARGERGFPGERGVQGPPGPA--GPRGNNGAPGNDGAKGDTGAPG 705

Query: 99  GPHRRGGEGLE 67
            P  +G  GL+
Sbjct: 706 APGSQGAPGLQ 716



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>CO1A1_MOUSE (P11087) Collagen alpha-1(I) chain precursor|
          Length = 1453

 Score = 30.4 bits (67), Expect = 4.0
 Identities = 24/71 (33%), Positives = 29/71 (40%), Gaps = 1/71 (1%)
 Frame = -3

Query: 276 DQAVPGRALGANGPV-ERVSRQHRDDHRKDRNPGPVLGNQLGRGAATGQDDNQSGPGLVG 100
           +Q VPG  LGA GP   R  R    +      PGP      G   A G D  +   G  G
Sbjct: 649 EQGVPGD-LGAPGPSGARGERGFPGERGVQGPPGPA--GPRGNNGAPGNDGAKGDTGAPG 705

Query: 99  GPHRRGGEGLE 67
            P  +G  GL+
Sbjct: 706 APGSQGAPGLQ 716



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>EBNA1_EBV (P03211) Epstein-Barr nuclear antigen 1 (EBV nuclear antigen 1)|
           (EBNA-1)
          Length = 641

 Score = 30.4 bits (67), Expect = 4.0
 Identities = 18/50 (36%), Positives = 20/50 (40%)
 Frame = -3

Query: 192 DRNPGPVLGNQLGRGAATGQDDNQSGPGLVGGPHRRGGEGLERAHREGCG 43
           D  PG   GN LG    T   +   G     GP RRGG+   R    G G
Sbjct: 3   DEGPGTGPGNGLGEKGDTSGPEGSGG----SGPQRRGGDNHGRGRGRGRG 48



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>IE63_HHV1E (P36295) Transcriptional regulator IE63 (VMW63) (ICP27)|
          Length = 511

 Score = 30.0 bits (66), Expect = 5.3
 Identities = 23/63 (36%), Positives = 27/63 (42%), Gaps = 3/63 (4%)
 Frame = -3

Query: 261 GRALGANGPVERVSRQHRDDHRKDRNPG--PVLGNQLGRGAATGQD-DNQSGPGLVGGPH 91
           GR  G  G  + +S   R   R +RNPG  P  G   G GA  G+       P   GGP 
Sbjct: 147 GRGRGGPGAADGLSDPRRRAPRTNRNPGDRPGAGWTDGPGAPHGEAWRGSEQPDPPGGPR 206

Query: 90  RRG 82
            RG
Sbjct: 207 TRG 209



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>NOLC_RHIFR (P26508) Protein nolC|
          Length = 392

 Score = 30.0 bits (66), Expect = 5.3
 Identities = 28/83 (33%), Positives = 33/83 (39%), Gaps = 2/83 (2%)
 Frame = -3

Query: 321 GLGGAFGKERDQASVDQAVPGRALGANGPVERVSRQH--RDDHRKDRNPGPVLGNQLGRG 148
           G+G  FG             G A G+ G   R  R+H  RDD R  R+  P+LG    R 
Sbjct: 77  GMGAGFGN------------GFAGGSAGGTSRHFRRHLRRDDGR--RSSAPLLGRSRTR- 121

Query: 147 AATGQDDNQSGPGLVGGPHRRGG 79
                     GP L  G H RGG
Sbjct: 122 ---------CGPSLQHGDHPRGG 135



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>CO1A1_CANFA (Q9XSJ7) Collagen alpha-1(I) chain precursor|
          Length = 1460

 Score = 30.0 bits (66), Expect = 5.3
 Identities = 24/71 (33%), Positives = 29/71 (40%), Gaps = 1/71 (1%)
 Frame = -3

Query: 276 DQAVPGRALGANGPV-ERVSRQHRDDHRKDRNPGPVLGNQLGRGAATGQDDNQSGPGLVG 100
           +Q VPG  LGA GP   R  R    +      PGP      G   A G D  +   G  G
Sbjct: 656 EQGVPGD-LGAPGPSGARGERGFPGERGVQGPPGPA--GPRGANGAPGNDGAKGDAGAPG 712

Query: 99  GPHRRGGEGLE 67
            P  +G  GL+
Sbjct: 713 APGSQGAPGLQ 723



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>CO3A1_BOVIN (P04258) Collagen alpha-1(III) chain|
          Length = 1049

 Score = 30.0 bits (66), Expect = 5.3
 Identities = 32/118 (27%), Positives = 42/118 (35%)
 Frame = +3

Query: 3    PGTTTPSSRXXDQGRTPPDEPARVPRLLGGADRQQGQGHSDCRPDPWRHHGQAGCQVPAQ 182
            PG   P+ +  D+G T P  P+  P   G       QG    + +     G+ G  +  +
Sbjct: 896  PGPVGPAGKSGDRGETGPAGPSGAPGPAGSRGPPGPQGPRGDKGET----GERGA-MGIK 950

Query: 183  GSDPFGGRPGAXXXXXXXXXXXXGPCQAQPDLQRPDPAPCRRLRQGHRLRVDGGDPPG 356
            G   F G PGA            GP   Q  +  P PA       G R  V    PPG
Sbjct: 951  GHRGFPGNPGA--------PGSPGPAGHQGAVGSPGPA-------GPRGPVGPSGPPG 993



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>OSA_DROME (Q8IN94) Trithorax group protein osa (Protein eyelid)|
          Length = 2716

 Score = 30.0 bits (66), Expect = 5.3
 Identities = 37/139 (26%), Positives = 46/139 (33%), Gaps = 16/139 (11%)
 Frame = +3

Query: 3    PGTTTPSSRXXDQGRTPPDEPARVPRLLGG---ADRQQGQGHSDCRPDPWRH-HGQAGCQ 170
            PG   P  +   QG+ PP      P + GG   A +Q G G     P P +H    AG  
Sbjct: 1290 PGPPPPQQQQGQQGQQPP------PSVGGGPPPAPQQHGPG--QVPPSPQQHVRPAAGAP 1341

Query: 171  VPAQGS-----------DPFGGRPGAXXXXXXXXXXXXGPCQAQPDLQRPDPAPCRRLRQ 317
             P  GS            P+  +PGA                 QP  Q P   P +    
Sbjct: 1342 YPPGGSGYPTPVSRTPGSPYPSQPGAYGQYGSSDQYNATGPPGQPFGQGPGQYPPQNRNM 1401

Query: 318  GHRLRVDGGDPP-GCAQVG 371
                  +G  PP G  Q G
Sbjct: 1402 YPPYGPEGEAPPTGANQYG 1420



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>CO1A1_HUMAN (P02452) Collagen alpha-1(I) chain precursor|
          Length = 1464

 Score = 30.0 bits (66), Expect = 5.3
 Identities = 24/71 (33%), Positives = 29/71 (40%), Gaps = 1/71 (1%)
 Frame = -3

Query: 276 DQAVPGRALGANGPV-ERVSRQHRDDHRKDRNPGPVLGNQLGRGAATGQDDNQSGPGLVG 100
           +Q VPG  LGA GP   R  R    +      PGP      G   A G D  +   G  G
Sbjct: 660 EQGVPGD-LGAPGPSGARGERGFPGERGVQGPPGPA--GPRGANGAPGNDGAKGDAGAPG 716

Query: 99  GPHRRGGEGLE 67
            P  +G  GL+
Sbjct: 717 APGSQGAPGLQ 727



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>LAMC2_HORSE (Q8HZI9) Laminin gamma-2 chain precursor (Laminin 5 gamma 2|
           subunit)
          Length = 1190

 Score = 29.6 bits (65), Expect = 6.9
 Identities = 16/43 (37%), Positives = 22/43 (51%), Gaps = 2/43 (4%)
 Frame = +3

Query: 252 GPCQAQPDLQRPDPAP--CRRLRQGHRLRVDGGDPPGCAQVGC 374
           GPC +   + +P      C R R G+   +DGG+P GC Q  C
Sbjct: 148 GPCDSGRCVCKPAVTGERCDRCRPGY-YHLDGGNPQGCTQCFC 189



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>KPYK_METEX (O05118) Pyruvate kinase (EC 2.7.1.40) (PK)|
          Length = 483

 Score = 29.6 bits (65), Expect = 6.9
 Identities = 24/135 (17%), Positives = 59/135 (43%), Gaps = 5/135 (3%)
 Frame = +1

Query: 70  ESLASSAVRTANKARATLIVVLTRGGTTAKLVAKYRPRVPILSVVVPVLTTDSFDWTISS 249
           +++A++A +         I+  T  G+T   +A+ RP   ++++                
Sbjct: 360 DAIAAAAHQIVEALSLRSIMAWTHSGSTVLRLARARPNASVIALT-------------PK 406

Query: 250 EGPARHSLIYRGLIPLLAEGSAKATDSESTEEILQAALKSAVKKQLCKAGDAVVVLHRI- 426
              AR   +  G+ P++ +      D+   +++   A K AV+++  + GD V+++  + 
Sbjct: 407 RETARRLTMAWGVHPIVTK------DASDVDDMAFRAAKFAVRERFAEIGDRVIIVAGVP 460

Query: 427 ----GVASVIKICTV 459
               G  ++++I  V
Sbjct: 461 FGIPGATNMVRIAFV 475



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>PO4F1_HUMAN (Q01851) POU domain, class 4, transcription factor 1|
           (Brain-specific homeobox/POU domain protein 3A) (Brn-3A)
           (Oct-T1) (Homeobox/POU domain protein RDC-1)
          Length = 423

 Score = 29.6 bits (65), Expect = 6.9
 Identities = 20/61 (32%), Positives = 22/61 (36%), Gaps = 14/61 (22%)
 Frame = -3

Query: 213 HRDDHRKDRNPGPVL--------------GNQLGRGAATGQDDNQSGPGLVGGPHRRGGE 76
           H   H +   PG +L              G   G GAA G      GPG  GGP   GG 
Sbjct: 103 HHHHHHQALEPGDLLDHISSPSLALMAGAGGAGGAGAAAGGGGAHDGPGGGGGPGGGGGP 162

Query: 75  G 73
           G
Sbjct: 163 G 163



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>VG16_BPP22 (Q01146) DNA transfer protein gp16|
          Length = 609

 Score = 29.3 bits (64), Expect = 9.0
 Identities = 24/83 (28%), Positives = 39/83 (46%), Gaps = 2/83 (2%)
 Frame = -3

Query: 285 ASVDQAVPGRALGANGPVERVSRQHRDDHRKDRNPGPVLGNQLGRGAATGQDDNQSGPGL 106
           A+VD+   G+A  A     + + Q  +  + +++     G+ L  G + GQ   Q+G GL
Sbjct: 23  AAVDEYFAGQASAAE---TQPAEQQEEPQQPEQSLMQRAGDLLTGGQSAGQIAEQAGRGL 79

Query: 105 VGGPH--RRGGEGLERAHREGCG 43
           V  P    +GG  L  A  +G G
Sbjct: 80  VNIPFDVLQGGASLINAISQGLG 102



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>NONA_DROME (Q04047) Protein no-on-transient A (Puff-specific protein Bj6)|
          Length = 700

 Score = 29.3 bits (64), Expect = 9.0
 Identities = 16/57 (28%), Positives = 25/57 (43%)
 Frame = -3

Query: 243 NGPVERVSRQHRDDHRKDRNPGPVLGNQLGRGAATGQDDNQSGPGLVGGPHRRGGEG 73
           N P    + Q++ +   ++      G    +    GQ  NQ GPG  GG   +GG+G
Sbjct: 139 NEPATAAAGQNQANQNANKGQNQRQGQNQNQNQVHGQG-NQGGPGNQGGAGNQGGQG 194



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>CLIC6_MOUSE (Q8BHB9) Chloride intracellular channel 6|
          Length = 596

 Score = 29.3 bits (64), Expect = 9.0
 Identities = 30/108 (27%), Positives = 38/108 (35%), Gaps = 3/108 (2%)
 Frame = +3

Query: 39  QGRTPPDEPARVPRLLGGA--DRQQGQGHSDCRPDPWRHHGQAGCQVPAQGSDPFGGRPG 212
           +GR   +E A  PR LG     R  G+    C  D     G  G Q     + P    PG
Sbjct: 35  EGREASEEAAEAPRDLGAGVEARASGKEEGGCGQD----EGTGGAQAQDPRTGPEAETPG 90

Query: 213 AXXXXXXXXXXXXGPCQAQPDLQRPDPAPCRRLRQGHRLRVDG-GDPP 353
           A             P  A P  Q  + AP  +  QG    +D  G+ P
Sbjct: 91  ASGAPGEAEAAERDPEGAIP--QGAEEAPSAQQVQGMSSGLDSQGEAP 136



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>ACON_STAAW (P63434) Aconitate hydratase (EC 4.2.1.3) (Citrate hydro-lyase)|
           (Aconitase)
          Length = 901

 Score = 29.3 bits (64), Expect = 9.0
 Identities = 22/72 (30%), Positives = 32/72 (44%), Gaps = 3/72 (4%)
 Frame = -3

Query: 303 GKERDQASVDQAVPGRALGANGPVERVSRQHRDDHRKDRNPGPVLGNQ--LGRGA-ATGQ 133
           GK  D  + D   P  A+G + P  +  + H+   R+  + G   GN   + RG  A  +
Sbjct: 675 GKFGDSVTTDHISPAGAIGKDTPAGKYLQDHQVPIREFNSYGSRRGNHEVMVRGTFANIR 734

Query: 132 DDNQSGPGLVGG 97
             NQ  PG  GG
Sbjct: 735 IKNQLAPGTEGG 746



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>ACON_STAAS (Q6G9K9) Aconitate hydratase (EC 4.2.1.3) (Citrate hydro-lyase)|
           (Aconitase)
          Length = 901

 Score = 29.3 bits (64), Expect = 9.0
 Identities = 22/72 (30%), Positives = 32/72 (44%), Gaps = 3/72 (4%)
 Frame = -3

Query: 303 GKERDQASVDQAVPGRALGANGPVERVSRQHRDDHRKDRNPGPVLGNQ--LGRGA-ATGQ 133
           GK  D  + D   P  A+G + P  +  + H+   R+  + G   GN   + RG  A  +
Sbjct: 675 GKFGDSVTTDHISPAGAIGKDTPAGKYLQDHQVPIREFNSYGSRRGNHEVMVRGTFANIR 734

Query: 132 DDNQSGPGLVGG 97
             NQ  PG  GG
Sbjct: 735 IKNQLAPGTEGG 746



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>ACON_STAAR (Q6GH55) Aconitate hydratase (EC 4.2.1.3) (Citrate hydro-lyase)|
           (Aconitase)
          Length = 901

 Score = 29.3 bits (64), Expect = 9.0
 Identities = 22/72 (30%), Positives = 32/72 (44%), Gaps = 3/72 (4%)
 Frame = -3

Query: 303 GKERDQASVDQAVPGRALGANGPVERVSRQHRDDHRKDRNPGPVLGNQ--LGRGA-ATGQ 133
           GK  D  + D   P  A+G + P  +  + H+   R+  + G   GN   + RG  A  +
Sbjct: 675 GKFGDSVTTDHISPAGAIGKDTPAGKYLQDHQVPIREFNSYGSRRGNHEVMVRGTFANIR 734

Query: 132 DDNQSGPGLVGG 97
             NQ  PG  GG
Sbjct: 735 IKNQLAPGTEGG 746



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>ACON_STAAN (P99148) Aconitate hydratase (EC 4.2.1.3) (Citrate hydro-lyase)|
           (Aconitase)
          Length = 901

 Score = 29.3 bits (64), Expect = 9.0
 Identities = 22/72 (30%), Positives = 32/72 (44%), Gaps = 3/72 (4%)
 Frame = -3

Query: 303 GKERDQASVDQAVPGRALGANGPVERVSRQHRDDHRKDRNPGPVLGNQ--LGRGA-ATGQ 133
           GK  D  + D   P  A+G + P  +  + H+   R+  + G   GN   + RG  A  +
Sbjct: 675 GKFGDSVTTDHISPAGAIGKDTPAGKYLQDHQVPIREFNSYGSRRGNHEVMVRGTFANIR 734

Query: 132 DDNQSGPGLVGG 97
             NQ  PG  GG
Sbjct: 735 IKNQLAPGTEGG 746



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>ACON_STAAM (P63433) Aconitate hydratase (EC 4.2.1.3) (Citrate hydro-lyase)|
           (Aconitase)
          Length = 901

 Score = 29.3 bits (64), Expect = 9.0
 Identities = 22/72 (30%), Positives = 32/72 (44%), Gaps = 3/72 (4%)
 Frame = -3

Query: 303 GKERDQASVDQAVPGRALGANGPVERVSRQHRDDHRKDRNPGPVLGNQ--LGRGA-ATGQ 133
           GK  D  + D   P  A+G + P  +  + H+   R+  + G   GN   + RG  A  +
Sbjct: 675 GKFGDSVTTDHISPAGAIGKDTPAGKYLQDHQVPIREFNSYGSRRGNHEVMVRGTFANIR 734

Query: 132 DDNQSGPGLVGG 97
             NQ  PG  GG
Sbjct: 735 IKNQLAPGTEGG 746



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>ACON_STAAC (Q5HG69) Aconitate hydratase (EC 4.2.1.3) (Citrate hydro-lyase)|
           (Aconitase)
          Length = 901

 Score = 29.3 bits (64), Expect = 9.0
 Identities = 22/72 (30%), Positives = 32/72 (44%), Gaps = 3/72 (4%)
 Frame = -3

Query: 303 GKERDQASVDQAVPGRALGANGPVERVSRQHRDDHRKDRNPGPVLGNQ--LGRGA-ATGQ 133
           GK  D  + D   P  A+G + P  +  + H+   R+  + G   GN   + RG  A  +
Sbjct: 675 GKFGDSVTTDHISPAGAIGKDTPAGKYLQDHQVPIREFNSYGSRRGNHEVMVRGTFANIR 734

Query: 132 DDNQSGPGLVGG 97
             NQ  PG  GG
Sbjct: 735 IKNQLAPGTEGG 746



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>CI010_HUMAN (Q9NZB2) Protein C9orf10|
          Length = 1069

 Score = 29.3 bits (64), Expect = 9.0
 Identities = 22/80 (27%), Positives = 29/80 (36%)
 Frame = -2

Query: 352  GGSPPSTLSLWPWRSLRQGAGSGLCRSGCAWQGPRXXXXXXXXXXSAPGRPPKGSEPWAG 173
            GG    T++  P+R+ R  A SG C    A+ G              P     G    AG
Sbjct: 895  GGPYGETVATGPYRAFRVAAASGHCG---AFSGSDSSRTSKSQGGVQPIPSQGGKLEIAG 951

Query: 172  TWQPAWPWCRHGSGRQSEWP 113
            T    W   R G G +  +P
Sbjct: 952  TVVGHWAGSRRGRGGRGPFP 971


  Database: uniprot_sprot.fasta
    Posted date:  May 25, 2006  5:36 PM
  Number of letters in database: 80,573,946
  Number of sequences in database:  219,361
  
Lambda     K      H
   0.318    0.135    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 86,505,679
Number of Sequences: 219361
Number of extensions: 1932602
Number of successful extensions: 7342
Number of sequences better than 10.0: 103
Number of HSP's better than 10.0 without gapping: 6564
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 7305
length of database: 80,573,946
effective HSP length: 107
effective length of database: 57,102,319
effective search space used: 5196311029
frameshift window, decay const: 50,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
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