>INVS_CANFA (Q6JAN1) Inversin (Inversion of embryo turning protein)|
            (Nephrocystin-2)
          Length = 1081

 Score = 35.4 bits (80), Expect = 0.11
 Identities = 35/111 (31%), Positives = 47/111 (42%), Gaps = 8/111 (7%)
 Frame = +3

Query: 159  RRCSLGRSWAH--GCRRRATAGKRG------IRHIRRQDTHSPRKGAPIRSEDG*DGRGC 314
            +RC  G+ +     C R A  G  G         + +QD H  RK  P R +D      C
Sbjct: 734  QRCDKGKGFLKQPSCLRVAGPGDEGEDPGWAAASLPQQDGH--RK--PSRRQDTASKAKC 789

Query: 315  ARQKVCRRLMALHGTSARHGSDEGPAGATGPGSSRQRTAVRGPSPRDHGLP 467
              QK  RR+  L G   RH     PAG++ PGS++      GP+   H  P
Sbjct: 790  TSQK--RRVQELRG--GRHS----PAGSSRPGSAKGEVVHAGPNALQHRTP 832

>ULK1_HUMAN (O75385) Serine/threonine-protein kinase ULK1 (EC 2.7.11.1)|
           (Unc-51-like kinase 1)
          Length = 1050

 Score = 33.5 bits (75), Expect = 0.41
 Identities = 24/77 (31%), Positives = 32/77 (41%), Gaps = 2/77 (2%)
 Frame = -3

Query: 505 PASRSCS-SSFKQAGRPWSRGLGPRTAVRCREDPGPVAPAGP-SSEPCRADVPCNAMSRL 332
           P S  CS SS   +    S G  P  +  C   P P   AGP SS  C A VP    +++
Sbjct: 379 PDSLMCSGSSLVASAGLESHGRTPSPSPPCSSSPSPSGRAGPFSSSRCGASVPIPVPTQV 438

Query: 331 QTFCRAHPRPSQPSSLR 281
           Q + R       P+  +
Sbjct: 439 QNYQRIERNLQSPTQFQ 455

>CO1A2_RABIT (Q28668) Collagen alpha-2(I) chain precursor (Fragment)|
          Length = 526

 Score = 33.5 bits (75), Expect = 0.41
 Identities = 31/101 (30%), Positives = 40/101 (39%), Gaps = 5/101 (4%)
 Frame = +3

Query: 168 SLGRSWAHGCRRRATAGKRG-IRHIRRQDTHSPRKGAPIRSEDG*DG----RGCARQKVC 332
           S+G +  HG   R   G  G I  +       P     IR + G  G    RG    K  
Sbjct: 128 SVGPTGKHG--NRGEPGPAGSIGPVGAAGPRGPSGPQGIRGDKGEPGDKGPRGLPGIKGH 185

Query: 333 RRLMALHGTSARHGSDEGPAGATGPGSSRQRTAVRGPSPRD 455
             L  L G + +HG D+G  GA GP   R      GP+ +D
Sbjct: 186 NGLQGLPGLAGQHG-DQGAPGAVGPAGPRGPAGPTGPAGKD 225

>CO1A2_CHICK (P02467) Collagen alpha-2(I) chain precursor (Fragments)|
          Length = 1362

 Score = 33.1 bits (74), Expect = 0.54
 Identities = 24/65 (36%), Positives = 30/65 (46%), Gaps = 3/65 (4%)
 Frame = +3

Query: 282  RSEDG*DG-RGCARQKVCRRLMALHGTSARHGSDEGPAGATGPGSSRQRTAVRGPSPRD- 455
            + E G  G RG    K    L  L G + +HG D+GP G  GP   R      GP  +D 
Sbjct: 1006 KGEPGDKGHRGLPGLKGHNGLQGLPGLAGQHG-DQGPPGNNGPAGPRGPPGPSGPPGKDG 1064

Query: 456  -HGLP 467
             +GLP
Sbjct: 1065 RNGLP 1069

>M4K1_HUMAN (Q92918) Mitogen-activated protein kinase kinase kinase kinase 1|
           (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 1) (MEK
           kinase kinase 1) (MEKKK 1) (Hematopoietic progenitor
           kinase)
          Length = 833

 Score = 32.3 bits (72), Expect = 0.92
 Identities = 17/38 (44%), Positives = 22/38 (57%), Gaps = 4/38 (10%)
 Frame = -2

Query: 200 PTAVRPGPPQRASSPHLSA----PLLGPCTRGVEDPLL 99
           P + RPGPP   SSPHL+A     L  P +R ++ P L
Sbjct: 434 PNSPRPGPPPSTSSPHLTAHSEPSLWNPPSRELDKPPL 471

>INVS_HUMAN (Q9Y283) Inversin (Inversion of embryo turning homolog)|
            (Nephrocystin-2)
          Length = 1065

 Score = 32.0 bits (71), Expect = 1.2
 Identities = 31/106 (29%), Positives = 41/106 (38%), Gaps = 4/106 (3%)
 Frame = +3

Query: 162  RCSLGRSWAH--GCRRRATAGKRGIRHIRRQDTHSPRKG--APIRSEDG*DGRGCARQKV 329
            RC+ G+ +     C R A   ++G    R   +  P      P R  D      CA QK 
Sbjct: 734  RCAKGKGFVKQPSCIRVAGPDEKGEDSRRAAASLPPHDSHWKPSRRHDTEPKAKCAPQK- 792

Query: 330  CRRLMALHGTSARHGSDEGPAGATGPGSSRQRTAVRGPSPRDHGLP 467
             RR   L G          PAG++ PGS+R      G +P  H  P
Sbjct: 793  -RRTQELRGGRC------SPAGSSRPGSARGEAVHAGQNPPHHRTP 831

>PAKM_DROME (Q9VXE5) Serine/threonine-protein kinase PAK mbt (EC 2.7.11.1)|
           (p21-activated kinase-related protein) (Protein mushroom
           bodies tiny)
          Length = 639

 Score = 31.6 bits (70), Expect = 1.6
 Identities = 24/89 (26%), Positives = 34/89 (38%), Gaps = 10/89 (11%)
 Frame = +2

Query: 20  PLQVLEPXXHPVQVLGP---------GVLLPHNSNIAAGLLLHECTGPIEERTNAAKMLV 172
           P+  + P  HP+   GP         G++LP  S++A    L   + P   R       V
Sbjct: 103 PMNPMAPGAHPMMSHGPGMMMPPETGGIVLPKTSHVARSNSLRSSSPPRVRRVANVPPSV 162

Query: 173 GEVLGARLSAT-GDGGEAGDPPHPEAGHP 256
            E  G   + T G GG +     P   HP
Sbjct: 163 PEEEGPPAAGTPGVGGASSGGFKPPGAHP 191

>CO1A2_BOVIN (P02465) Collagen alpha-2(I) chain precursor|
          Length = 1364

 Score = 31.6 bits (70), Expect = 1.6
 Identities = 22/63 (34%), Positives = 27/63 (42%), Gaps = 4/63 (6%)
 Frame = +3

Query: 279  IRSEDG*DG----RGCARQKVCRRLMALHGTSARHGSDEGPAGATGPGSSRQRTAVRGPS 446
            IR + G  G    RG    K    L  L G +  HG D+G  GA GP   R      GP+
Sbjct: 1002 IRGDKGEPGDKGPRGLPGLKGHNGLQGLPGLAGHHG-DQGAPGAVGPAGPRGPAGPSGPA 1060

Query: 447  PRD 455
             +D
Sbjct: 1061 GKD 1063

>Y3672_STRCO (P40180) Putative glycosyl transferase SCO3672 (EC 2.-.-.-)|
          Length = 411

 Score = 31.6 bits (70), Expect = 1.6
 Identities = 26/77 (33%), Positives = 34/77 (44%), Gaps = 1/77 (1%)
 Frame = +3

Query: 207 ATAGKRGIRHIRRQDTHSPRKGAPIRSEDG*DGRGCARQKVCRRLMALHGTSARHGSDEG 386
           A AG  G+  +R       R+GA +R+     GRG     V RR        AR G  + 
Sbjct: 313 AAAGVLGLLRVRVYGPARLRRGAGVRAPVRRAGRGARAWAVVRRPRTAM-RRARAGVSQA 371

Query: 387 PAGATG-PGSSRQRTAV 434
           P GATG  G +  R A+
Sbjct: 372 PRGATGAAGGASFRAAI 388

>COGA1_HUMAN (Q07092) Collagen alpha-1(XVI) chain precursor|
          Length = 1603

 Score = 31.2 bits (69), Expect = 2.0
 Identities = 22/63 (34%), Positives = 27/63 (42%), Gaps = 3/63 (4%)
 Frame = -3

Query: 508 IPASRSCSSSFKQAGRPWSRGLGPRTAVRCREDPGPVAPA---GPSSEPCRADVPCNAMS 338
           +P  +    +F +AG   S G            PGPV PA   G   EPC    PC A+S
Sbjct: 593 VPGLKGEKGNFGEAGPAGSPG-----------PPGPVGPAGIKGAKGEPCE---PCPALS 638

Query: 337 RLQ 329
            LQ
Sbjct: 639 NLQ 641

>SH23A_HUMAN (Q9BRG2) SH2 domain-containing protein 3A (Novel SH2-containing|
           protein 1)
          Length = 576

 Score = 31.2 bits (69), Expect = 2.0
 Identities = 16/38 (42%), Positives = 21/38 (55%)
 Frame = +2

Query: 98  IAAGLLLHECTGPIEERTNAAKMLVGEVLGARLSATGD 211
           +A  L +  C+GP+EER  A + LV   L  R  A GD
Sbjct: 372 LAGALAVLGCSGPLEERAAALRGLVELALALRPGAAGD 409

>ASXL1_HUMAN (Q8IXJ9) Putative Polycomb group protein ASXL1 (Additional sex|
           combs-like protein 1)
          Length = 1541

 Score = 31.2 bits (69), Expect = 2.0
 Identities = 15/32 (46%), Positives = 19/32 (59%)
 Frame = +2

Query: 185 GARLSATGDGGEAGDPPHPEAGHPFPKEGSSD 280
           G R S++GDGGEA   P P  G   P + +SD
Sbjct: 659 GGRGSSSGDGGEACGHPEPRGGPSTPGKCTSD 690

>CO1A2_CANFA (O46392) Collagen alpha-2(I) chain precursor|
          Length = 1366

 Score = 31.2 bits (69), Expect = 2.0
 Identities = 25/84 (29%), Positives = 34/84 (40%)
 Frame = +3

Query: 204  RATAGKRGIRHIRRQDTHSPRKGAPIRSEDG*DGRGCARQKVCRRLMALHGTSARHGSDE 383
            R  +G +GIR     D   P +  P         RG    K    L  L G + +HG D+
Sbjct: 996  RGPSGPQGIRG----DKGEPGEKGP---------RGLPGLKGHNGLQGLPGLAGQHG-DQ 1041

Query: 384  GPAGATGPGSSRQRTAVRGPSPRD 455
            G  G+ GP   R      GP+ +D
Sbjct: 1042 GAPGSVGPAGPRGPAGPSGPAGKD 1065

>XYLT1_CANFA (Q5QQ56) Xylosyltransferase 1 (EC 2.4.2.26) (Xylosyltransferase I)|
           (Peptide O-xylosyltransferase 1)
          Length = 950

 Score = 30.8 bits (68), Expect = 2.7
 Identities = 15/40 (37%), Positives = 17/40 (42%)
 Frame = -3

Query: 409 PGPVAPAGPSSEPCRADVPCNAMSRLQTFCRAHPRPSQPS 290
           PGP AP G          P  A +R    C   PRP QP+
Sbjct: 74  PGPAAPLGACCGGGGRGPPARARARALAGCPEEPRPQQPA 113

>CCNL1_RAT (Q9R1Q2) Cyclin-L1 (Cyclin-L) (Cyclin Ania-6a)|
          Length = 527

 Score = 30.8 bits (68), Expect = 2.7
 Identities = 25/92 (27%), Positives = 39/92 (42%), Gaps = 4/92 (4%)
 Frame = +3

Query: 240 RRQDTHSPRKGAPIRSEDG*DGRGCARQKVCRRLMALHGTSARHGSDEGPAGATGPGSSR 419
           R+Q + SP  G    S+   + R  +R +   R  +   T  RH ++      T    SR
Sbjct: 369 RQQASKSPYNGVRKDSKRSRNSRSASRSRSRTRSRSRSHTPRRHYNNRRSRSGTYSSRSR 428

Query: 420 QRTAVRGPSPR---DHGLPAC-LKEEEQDLEA 503
            R+     SPR   +HG P    K   +DL++
Sbjct: 429 SRSRSHSESPRRHHNHGSPHLKAKHTREDLKS 460

>CAC1A_RABIT (P27884) Voltage-dependent P/Q-type calcium channel alpha-1A subunit|
            (Voltage-gated calcium channel alpha subunit Cav2.1)
            (Calcium channel, L type, alpha-1 polypeptide isoform 4)
            (Brain calcium channel I) (BI)
          Length = 2424

 Score = 30.4 bits (67), Expect = 3.5
 Identities = 28/102 (27%), Positives = 34/102 (33%), Gaps = 16/102 (15%)
 Frame = +3

Query: 192  GCRRRATAGKRGIRHIRRQD--------THSPRKGAP--------IRSEDG*DGRGCARQ 323
            G   R  AG    RH  RQ         + SPR G          +    G DG     +
Sbjct: 921  GEAERGKAGDPHRRHAHRQGVGGSGGSRSGSPRTGTADGEPRRHRVHRRPGEDGPDDKAE 980

Query: 324  KVCRRLMALHGTSARHGSDEGPAGATGPGSSRQRTAVRGPSP 449
            +  R         +  G  EGP G  G G  R+R    GP P
Sbjct: 981  RRGRHREGSRPARSGEGEAEGPDGGGGGGGERRRRHRHGPPP 1022

>CO1A2_HUMAN (P08123) Collagen alpha-2(I) chain precursor|
          Length = 1366

 Score = 30.4 bits (67), Expect = 3.5
 Identities = 25/84 (29%), Positives = 33/84 (39%)
 Frame = +3

Query: 204  RATAGKRGIRHIRRQDTHSPRKGAPIRSEDG*DGRGCARQKVCRRLMALHGTSARHGSDE 383
            R  +G +GIR     D   P +  P         RG    K    L  L G +  HG D+
Sbjct: 996  RGPSGPQGIRG----DKGEPGEKGP---------RGLPGFKGHNGLQGLPGIAGHHG-DQ 1041

Query: 384  GPAGATGPGSSRQRTAVRGPSPRD 455
            G  G+ GP   R      GP+ +D
Sbjct: 1042 GAPGSVGPAGPRGPAGPSGPAGKD 1065

>CCNL1_HUMAN (Q9UK58) Cyclin-L1 (Cyclin-L)|
          Length = 526

 Score = 30.4 bits (67), Expect = 3.5
 Identities = 23/88 (26%), Positives = 36/88 (40%), Gaps = 3/88 (3%)
 Frame = +3

Query: 240 RRQDTHSPRKGAPIRSEDG*DGRGCARQKVCRRLMALHGTSARHGSDEGPAGATGPGSSR 419
           R+Q + SP  G    S+   + R  +R +   R  +   T  RH ++      T    SR
Sbjct: 368 RQQASKSPYNGVRKDSKRSRNSRSASRSRSRTRSRSRSHTPRRHYNNRRSRSGTYSSRSR 427

Query: 420 QRTAVRGPSPR---DHGLPACLKEEEQD 494
            R+     SPR   +HG P    +  +D
Sbjct: 428 SRSRSHSESPRRHHNHGSPHLKAKHTRD 455

>M3K12_HUMAN (Q12852) Mitogen-activated protein kinase kinase kinase 12 (EC|
           2.7.11.25) (Mixed lineage kinase) (Leucine-zipper
           protein kinase) (ZPK) (Dual leucine zipper bearing
           kinase) (DLK) (MAPK-upstream kinase) (MUK)
          Length = 859

 Score = 29.6 bits (65), Expect = 5.9
 Identities = 17/48 (35%), Positives = 27/48 (56%), Gaps = 1/48 (2%)
 Frame = +2

Query: 137 IEERTNAAKMLVGEVLGAR-LSATGDGGEAGDPPHPEAGHPFPKEGSS 277
           + + ++++  L+   LG+R   ATG  G+ G PP P  G   P EGS+
Sbjct: 603 LRKMSSSSPDLLSAALGSRGRGATGGAGDPGSPP-PARGDTPPSEGSA 649

>CO020_HUMAN (Q9H611) Protein C15orf20|
          Length = 266

 Score = 29.6 bits (65), Expect = 5.9
 Identities = 15/38 (39%), Positives = 21/38 (55%)
 Frame = +3

Query: 390 AGATGPGSSRQRTAVRGPSPRDHGLPACLKEEEQDLEA 503
           A A GPG +  R  + GP PRD    + ++ EE+ L A
Sbjct: 125 AAAPGPGPASARAQLLGPRPRDFVTISPVQPEERRLRA 162

>KCNN1_HUMAN (Q92952) Small conductance calcium-activated potassium channel|
           protein 1 (SK1)
          Length = 561

 Score = 29.6 bits (65), Expect = 5.9
 Identities = 15/29 (51%), Positives = 16/29 (55%)
 Frame = +2

Query: 170 VGEVLGARLSATGDGGEAGDPPHPEAGHP 256
           VG  LG+     G G    DPP PEAGHP
Sbjct: 28  VGRPLGS-----GPGALGRDPPDPEAGHP 51

>C1QL3_MOUSE (Q9ESN4) Complement C1q-like protein 3 precursor (Gliacolin)|
          Length = 255

 Score = 29.6 bits (65), Expect = 5.9
 Identities = 17/40 (42%), Positives = 19/40 (47%)
 Frame = -3

Query: 472 QAGRPWSRGLGPRTAVRCREDPGPVAPAGPSSEPCRADVP 353
           +AGRP   G  PR        PGPV P G   EP R  +P
Sbjct: 65  EAGRPGKAG--PRGPPGEPGPPGPVGPPGEKGEPGRQGLP 102

>B4GT1_HUMAN (P15291) Beta-1,4-galactosyltransferase 1 (EC 2.4.1.-)|
           (Beta-1,4-GalTase 1) (Beta4Gal-T1) (b4Gal-T1)
           (UDP-galactose:beta-N-acetylglucosamine
           beta-1,4-galactosyltransferase 1) (UDP-Gal:beta-GlcNAc
           beta-1,4-galactosyltransferase 1) [Includes: L
          Length = 397

 Score = 29.6 bits (65), Expect = 5.9
 Identities = 15/39 (38%), Positives = 19/39 (48%)
 Frame = +3

Query: 366 RHGSDEGPAGATGPGSSRQRTAVRGPSPRDHGLPACLKE 482
           R G D  P   +GPG +   T+V  P      LPAC +E
Sbjct: 94  RPGGDSSPVVDSGPGPASNLTSVPVPHTTALSLPACPEE 132

>XKR4_PANTR (Q49LS4) XK-related protein 4|
          Length = 650

 Score = 29.3 bits (64), Expect = 7.8
 Identities = 22/60 (36%), Positives = 27/60 (45%), Gaps = 1/60 (1%)
 Frame = +3

Query: 300 DGRGCARQKVCRRLMALHGTSARHGSDEGPAGATGPGSSRQRTAVR-GPSPRDHGLPACL 476
           DG GC+R   C    A  G+SA  G   G AG  G G+      +R G   R + L  CL
Sbjct: 57  DGGGCSR---CCCCCAGSGSSAGSGGSGGVAGPGGGGAGSAALCLRLGREQRRYSLWDCL 113

>CO6A1_CHICK (P20785) Collagen alpha-1(VI) chain precursor|
          Length = 1019

 Score = 29.3 bits (64), Expect = 7.8
 Identities = 26/75 (34%), Positives = 29/75 (38%), Gaps = 6/75 (8%)
 Frame = +3

Query: 255 HSPRKGAPIRSEDG*DGR----GCARQKVCRRLMALHGTSARHGSDEGPAGATGPGSSRQ 422
           + P+ G     EDG  GR    G   +K         G     G DEG  GA GP   R 
Sbjct: 365 YGPKGGKGEPGEDGKPGRQGIPGSPGEKGAPGNRGEPGPLGETG-DEGSPGADGPPGERG 423

Query: 423 RTAVRGP--SPRDHG 461
               RGP  SP D G
Sbjct: 424 SNGERGPPGSPGDRG 438

>NADB_RHILO (Q98AV8) L-aspartate oxidase (EC 1.4.3.16) (LASPO) (Quinolinate|
           synthetase B)
          Length = 513

 Score = 29.3 bits (64), Expect = 7.8
 Identities = 18/51 (35%), Positives = 21/51 (41%)
 Frame = +1

Query: 310 DARGRRSVGGSWRCTEHQLGTVPMKDPQERRGLGLHGNERLCAXQVHETMA 462
           DA GR SV G W C E                 GLHG  RL +  + E +A
Sbjct: 346 DAEGRTSVSGLWACGEVAC-------------TGLHGANRLASNSLTEAVA 383

>VANB_PSEUH (O05617) Vanillate O-demethylase oxidoreductase (EC 1.14.13.-)|
           (Vanillate degradation ferredoxin-like protein)
          Length = 317

 Score = 29.3 bits (64), Expect = 7.8
 Identities = 14/36 (38%), Positives = 18/36 (50%)
 Frame = +2

Query: 119 HECTGPIEERTNAAKMLVGEVLGARLSATGDGGEAG 226
           H   GP +++ NAA +L  E  G  L   G GG  G
Sbjct: 163 HFDNGPDQQKLNAAALLAAEAEGTHLYVCGPGGFMG 198

>ATBF1_MOUSE (Q61329) Alpha-fetoprotein enhancer-binding protein (AT|
           motif-binding factor) (AT-binding transcription factor
           1)
          Length = 3726

 Score = 29.3 bits (64), Expect = 7.8
 Identities = 17/42 (40%), Positives = 22/42 (52%), Gaps = 5/42 (11%)
 Frame = -3

Query: 391 AGPSSEPCRADVPCN----AMSRLQTFCRAH-PRPSQPSSLR 281
           AGP +EP   +V CN    + S LQT+   H P    P +LR
Sbjct: 68  AGPPAEPASKEVSCNECSASFSSLQTYMEHHCPGTHPPPALR 109

>CABL2_HUMAN (Q9BTV7) CDK5 and ABL1 enzyme substrate 2 (Interactor with CDK3 2)|
           (Ik3-2)
          Length = 478

 Score = 29.3 bits (64), Expect = 7.8
 Identities = 18/50 (36%), Positives = 20/50 (40%), Gaps = 4/50 (8%)
 Frame = -3

Query: 466 GRPWSRGLG----PRTAVRCREDPGPVAPAGPSSEPCRADVPCNAMSRLQ 329
           GRP S G G    P      RE P P  P  P+  P R   P   +S  Q
Sbjct: 59  GRPPSLGPGGEKPPPPPAEAREPPAPPPPEPPTGLPARTPAPQGLLSPTQ 108


  Database: uniprot_sprot.fasta
    Posted date:  May 25, 2006  5:36 PM
  Number of letters in database: 80,573,946
  Number of sequences in database:  219,361
  
Lambda     K      H
   0.318    0.135    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 80,489,992
Number of Sequences: 219361
Number of extensions: 1797134
Number of successful extensions: 8054
Number of sequences better than 10.0: 29
Number of HSP's better than 10.0 without gapping: 6273
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 8000
length of database: 80,573,946
effective HSP length: 105
effective length of database: 57,541,041
effective search space used: 4488201198
frameshift window, decay const: 50,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)