>AP4S1_HUMAN (Q9Y587) AP-4 complex subunit sigma-1 (Adapter-related protein|
           complex 4 sigma-1 subunit) (Sigma subunit of AP-4) (AP-4
           adapter complex sigma subunit)
          Length = 144

 Score = 96.7 bits (239), Expect = 4e-20
 Identities = 39/74 (52%), Positives = 65/74 (87%)
 Frame = -3

Query: 446 IRFVLLVNKQGQTRLAQCYEHLSLDERRALEGEIIRKCLARTDQQCSFVEHRNYKVVYRR 267
           I+F L+VNKQGQTRL++ YEH+ +++R  LE E+I+ CL+R+++QCSF+E++++K++YR+
Sbjct: 2   IKFFLMVNKQGQTRLSKYYEHVDINKRTLLETEVIKSCLSRSNEQCSFIEYKDFKLIYRQ 61

Query: 266 YASLFFLVGVDNDE 225
           YA+LF +VGV++ E
Sbjct: 62  YAALFIVVGVNDTE 75

>AP4S1_MOUSE (Q9WVL1) AP-4 complex subunit sigma-1 (Adapter-related protein|
           complex 4 sigma-1 subunit) (Sigma subunit of AP-4) (AP-4
           adapter complex sigma subunit)
          Length = 144

 Score = 93.6 bits (231), Expect = 3e-19
 Identities = 38/74 (51%), Positives = 63/74 (85%)
 Frame = -3

Query: 446 IRFVLLVNKQGQTRLAQCYEHLSLDERRALEGEIIRKCLARTDQQCSFVEHRNYKVVYRR 267
           I+F L+VNKQGQTRL++ YEH+ +++R  LE E+ + CL+R+ +QCSF+E++++K++YR+
Sbjct: 2   IKFFLMVNKQGQTRLSKYYEHVDINKRALLETEVSKSCLSRSSEQCSFIEYKDFKLIYRQ 61

Query: 266 YASLFFLVGVDNDE 225
           YA+LF +VGV++ E
Sbjct: 62  YAALFVVVGVNDTE 75

>AP2S1_MAIZE (O50016) AP-2 complex subunit sigma-1 (Clathrin coat assembly|
           protein AP17) (Clathrin coat-associated protein AP17)
           (Plasma membrane adaptor AP-2 17 kDa protein) (Clathrin
           assembly protein 2 small chain)
          Length = 132

 Score = 70.1 bits (170), Expect = 4e-12
 Identities = 39/92 (42%), Positives = 57/92 (61%)
 Frame = -3

Query: 446 IRFVLLVNKQGQTRLAQCYEHLSLDERRALEGEIIRKCLARTDQQCSFVEHRNYKVVYRR 267
           IRF+LL N+QG+TRLA+ Y  L   E+  +E E+ R  + R  +  +FVE R +KV+YRR
Sbjct: 2   IRFILLQNRQGKTRLAKYYVPLEDSEKHKVEYEVHRLVVNRDPKFTNFVEFRTHKVIYRR 61

Query: 266 YASLFFLVGVDNDEASDRFCTCMLFSIFHEVL 171
           YA LFF + VD  +    +  C+   +F E+L
Sbjct: 62  YAGLFFSICVDITDNELAYLECI--HLFVEIL 91

>AP2S_NEUCR (Q7SAQ1) AP-2 complex subunit sigma (Clathrin assembly protein 2|
           small chain) (Adaptin small chain)
          Length = 143

 Score = 68.9 bits (167), Expect = 9e-12
 Identities = 42/93 (45%), Positives = 58/93 (62%), Gaps = 1/93 (1%)
 Frame = -3

Query: 446 IRFVLLVNKQGQTRLAQCYEHLSLDERRALEGEIIRKCLARTDQ-QCSFVEHRNYKVVYR 270
           + F+L+ N+QG+TRLA+ Y   S +E+  L+GEI R    R  + Q +FVE RN+KVVYR
Sbjct: 2   LSFILIQNRQGKTRLAKWYVPYSDEEKIKLKGEIHRLVAPRDQKYQSNFVEFRNHKVVYR 61

Query: 269 RYASLFFLVGVDNDEASDRFCTCMLFSIFHEVL 171
           RYA LFF   VD ++    +   + F  F EVL
Sbjct: 62  RYAGLFFCACVDTNDNELAYLEAIHF--FVEVL 92

>AP2S_GIBZE (Q4ICG5) AP-2 complex subunit sigma (Clathrin assembly protein 2|
           small chain) (Adaptin small chain)
          Length = 143

 Score = 67.4 bits (163), Expect = 3e-11
 Identities = 40/93 (43%), Positives = 57/93 (61%), Gaps = 1/93 (1%)
 Frame = -3

Query: 446 IRFVLLVNKQGQTRLAQCYEHLSLDERRALEGEIIRKCLARTDQ-QCSFVEHRNYKVVYR 270
           + F+L+ N+QG+TRLA+ Y   S +++  L+GE+ R    R  + Q +FVE RN K+VYR
Sbjct: 2   LSFILIQNRQGKTRLAKWYAPFSDEQKIKLKGEVHRLVAPRDQKYQSNFVEFRNNKIVYR 61

Query: 269 RYASLFFLVGVDNDEASDRFCTCMLFSIFHEVL 171
           RYA LFF   VD ++    F   + F  F EVL
Sbjct: 62  RYAGLFFCACVDTNDNELAFLEAIHF--FVEVL 92

>AP1S2_MOUSE (Q9DB50) AP-1 complex subunit sigma-2 (Adapter-related protein|
           complex 1 sigma-1B subunit) (Sigma-adaptin 1B) (Adaptor
           protein complex AP-1 sigma-1B subunit) (Golgi adaptor
           HA1/AP1 adaptin sigma-1B subunit) (Clathrin assembly
           protein complex
          Length = 160

 Score = 65.9 bits (159), Expect = 8e-11
 Identities = 29/74 (39%), Positives = 52/74 (70%)
 Frame = -3

Query: 446 IRFVLLVNKQGQTRLAQCYEHLSLDERRALEGEIIRKCLARTDQQCSFVEHRNYKVVYRR 267
           ++F+LL ++QG+ RL + Y  LS  E++ +  E+++  LAR  + CSF+E R+ K+VY+R
Sbjct: 1   MQFMLLFSRQGKLRLQKWYVPLSDKEKKKITRELVQTVLARKPKMCSFLEWRDLKIVYKR 60

Query: 266 YASLFFLVGVDNDE 225
           YASL+F   +++ +
Sbjct: 61  YASLYFCCAIEDQD 74

>AP2S1_RAT (P62744) AP-2 complex subunit sigma-1 (Adapter-related protein|
           complex 2 sigma-1 subunit) (Sigma-adaptin 3b) (Clathrin
           coat assembly protein AP17) (Clathrin coat-associated
           protein AP17) (Plasma membrane adaptor AP-2 17 kDa
           protein) (Clathrin a
          Length = 142

 Score = 65.9 bits (159), Expect = 8e-11
 Identities = 33/97 (34%), Positives = 56/97 (57%), Gaps = 2/97 (2%)
 Frame = -3

Query: 446 IRFVLLVNKQGQTRLAQCYEHLSLDERRALEGEIIRKCLARTDQQCSFVEHRNYKVVYRR 267
           IRF+L+ N+ G+TRLA+ Y     DE++ L  E+      R  +  +FVE RN+K++YRR
Sbjct: 2   IRFILIQNRAGKTRLAKWYMQFDDDEKQKLIEEVHAVVTVRDAKHTNFVEFRNFKIIYRR 61

Query: 266 YASLFFLVGVDNDEASDRFCTCM--LFSIFHEVLHQI 162
           YA L+F + VD ++ +  +   +     + +E  H +
Sbjct: 62  YAGLYFCICVDVNDNNLAYLEAIHNFVEVLNEYFHNV 98

>AP2S1_PONPY (Q5R940) AP-2 complex subunit sigma-1 (Adapter-related protein|
           complex 2 sigma-1 subunit) (Sigma-adaptin 3b) (Clathrin
           coat assembly protein AP17) (Clathrin coat-associated
           protein AP17) (Plasma membrane adaptor AP-2 17 kDa
           protein) (Clathrin
          Length = 142

 Score = 65.9 bits (159), Expect = 8e-11
 Identities = 33/97 (34%), Positives = 56/97 (57%), Gaps = 2/97 (2%)
 Frame = -3

Query: 446 IRFVLLVNKQGQTRLAQCYEHLSLDERRALEGEIIRKCLARTDQQCSFVEHRNYKVVYRR 267
           IRF+L+ N+ G+TRLA+ Y     DE++ L  E+      R  +  +FVE RN+K++YRR
Sbjct: 2   IRFILIQNRAGKTRLAKWYMQFDDDEKQKLIEEVHAVVTVRDAKHTNFVEFRNFKIIYRR 61

Query: 266 YASLFFLVGVDNDEASDRFCTCM--LFSIFHEVLHQI 162
           YA L+F + VD ++ +  +   +     + +E  H +
Sbjct: 62  YAGLYFCICVDVNDNNLAYLEAIHNFVEVLNEYFHNV 98

>AP2S1_MOUSE (P62743) AP-2 complex subunit sigma-1 (Adapter-related protein|
           complex 2 sigma-1 subunit) (Sigma-adaptin 3b) (Clathrin
           coat assembly protein AP17) (Clathrin coat-associated
           protein AP17) (Plasma membrane adaptor AP-2 17 kDa
           protein) (Clathrin
          Length = 142

 Score = 65.9 bits (159), Expect = 8e-11
 Identities = 33/97 (34%), Positives = 56/97 (57%), Gaps = 2/97 (2%)
 Frame = -3

Query: 446 IRFVLLVNKQGQTRLAQCYEHLSLDERRALEGEIIRKCLARTDQQCSFVEHRNYKVVYRR 267
           IRF+L+ N+ G+TRLA+ Y     DE++ L  E+      R  +  +FVE RN+K++YRR
Sbjct: 2   IRFILIQNRAGKTRLAKWYMQFDDDEKQKLIEEVHAVVTVRDAKHTNFVEFRNFKIIYRR 61

Query: 266 YASLFFLVGVDNDEASDRFCTCM--LFSIFHEVLHQI 162
           YA L+F + VD ++ +  +   +     + +E  H +
Sbjct: 62  YAGLYFCICVDVNDNNLAYLEAIHNFVEVLNEYFHNV 98

>AP2S1_HUMAN (P53680) AP-2 complex subunit sigma-1 (Adapter-related protein|
           complex 2 sigma-1 subunit) (Clathrin coat assembly
           protein AP17) (Clathrin coat-associated protein AP17)
           (Plasma membrane adaptor AP-2 17 kDa protein) (HA2 17
           kDa subunit) (Clathr
          Length = 142

 Score = 65.9 bits (159), Expect = 8e-11
 Identities = 33/97 (34%), Positives = 56/97 (57%), Gaps = 2/97 (2%)
 Frame = -3

Query: 446 IRFVLLVNKQGQTRLAQCYEHLSLDERRALEGEIIRKCLARTDQQCSFVEHRNYKVVYRR 267
           IRF+L+ N+ G+TRLA+ Y     DE++ L  E+      R  +  +FVE RN+K++YRR
Sbjct: 2   IRFILIQNRAGKTRLAKWYMQFDDDEKQKLIEEVHAVVTVRDAKHTNFVEFRNFKIIYRR 61

Query: 266 YASLFFLVGVDNDEASDRFCTCM--LFSIFHEVLHQI 162
           YA L+F + VD ++ +  +   +     + +E  H +
Sbjct: 62  YAGLYFCICVDVNDNNLAYLEAIHNFVEVLNEYFHNV 98

>AP1S2_HUMAN (P56377) AP-1 complex subunit sigma-2 (Adapter-related protein|
           complex 1 sigma-1B subunit) (Sigma-adaptin 1B) (Adaptor
           protein complex AP-1 sigma-1B subunit) (Golgi adaptor
           HA1/AP1 adaptin sigma-1B subunit) (Clathrin assembly
           protein complex
          Length = 157

 Score = 65.9 bits (159), Expect = 8e-11
 Identities = 29/74 (39%), Positives = 52/74 (70%)
 Frame = -3

Query: 446 IRFVLLVNKQGQTRLAQCYEHLSLDERRALEGEIIRKCLARTDQQCSFVEHRNYKVVYRR 267
           ++F+LL ++QG+ RL + Y  LS  E++ +  E+++  LAR  + CSF+E R+ K+VY+R
Sbjct: 1   MQFMLLFSRQGKLRLQKWYVPLSDKEKKKITRELVQTVLARKPKMCSFLEWRDLKIVYKR 60

Query: 266 YASLFFLVGVDNDE 225
           YASL+F   +++ +
Sbjct: 61  YASLYFCCAIEDQD 74

>AP1T1_YEAST (P35181) AP-1 complex subunit theta-1 (Theta(1)-adaptin) (Clathrin|
           coat assembly protein AP19) (Clathrin coat-associated
           protein AP19) (Golgi adaptor AP-1 19 kDa adaptin) (HA1
           19 kDa subunit) (Clathrin assembly protein complex 1
           small chain)
          Length = 156

 Score = 65.1 bits (157), Expect = 1e-10
 Identities = 28/73 (38%), Positives = 51/73 (69%)
 Frame = -3

Query: 446 IRFVLLVNKQGQTRLAQCYEHLSLDERRALEGEIIRKCLARTDQQCSFVEHRNYKVVYRR 267
           ++++LLV++QG+ RL + Y  +S  E+  +  ++    LAR  + C+ +E+ ++KVVY+R
Sbjct: 4   LKYLLLVSRQGKIRLKKWYTAMSAGEKAKIVKDLTPTILARKPKMCNIIEYNDHKVVYKR 63

Query: 266 YASLFFLVGVDND 228
           YASL+F+VG+  D
Sbjct: 64  YASLYFIVGMTPD 76

>AP1S1_MOUSE (P61967) AP-1 complex subunit sigma-1A (Adapter-related protein|
           complex 1 sigma-1A subunit) (Sigma-adaptin 1A) (Adaptor
           protein complex AP-1 sigma-1A subunit) (Golgi adaptor
           HA1/AP1 adaptin sigma-1A subunit) (Clathrin assembly
           protein complex
          Length = 158

 Score = 64.7 bits (156), Expect = 2e-10
 Identities = 31/74 (41%), Positives = 50/74 (67%)
 Frame = -3

Query: 446 IRFVLLVNKQGQTRLAQCYEHLSLDERRALEGEIIRKCLARTDQQCSFVEHRNYKVVYRR 267
           +RF+LL ++QG+ RL + Y   S  ER+ +  E+++  LAR  + CSF+E R+ KVVY+R
Sbjct: 2   MRFMLLFSRQGKLRLQKWYLATSDKERKKMVRELMQVVLARKPKMCSFLEWRDLKVVYKR 61

Query: 266 YASLFFLVGVDNDE 225
           YASL+F   ++  +
Sbjct: 62  YASLYFCCAIEGQD 75

>AP1S1_HUMAN (P61966) AP-1 complex subunit sigma-1A (Adapter-related protein|
           complex 1 sigma-1A subunit) (Sigma-adaptin 1A) (Adaptor
           protein complex AP-1 sigma-1A subunit) (Golgi adaptor
           HA1/AP1 adaptin sigma-1A subunit) (Clathrin assembly
           protein complex
          Length = 158

 Score = 64.7 bits (156), Expect = 2e-10
 Identities = 31/74 (41%), Positives = 50/74 (67%)
 Frame = -3

Query: 446 IRFVLLVNKQGQTRLAQCYEHLSLDERRALEGEIIRKCLARTDQQCSFVEHRNYKVVYRR 267
           +RF+LL ++QG+ RL + Y   S  ER+ +  E+++  LAR  + CSF+E R+ KVVY+R
Sbjct: 2   MRFMLLFSRQGKLRLQKWYLATSDKERKKMVRELMQVVLARKPKMCSFLEWRDLKVVYKR 61

Query: 266 YASLFFLVGVDNDE 225
           YASL+F   ++  +
Sbjct: 62  YASLYFCCAIEGQD 75

>AP2S_ASPFU (Q4WS49) AP-2 complex subunit sigma (Clathrin assembly protein 2|
           small chain) (Adaptin small chain)
          Length = 145

 Score = 61.6 bits (148), Expect = 1e-09
 Identities = 41/96 (42%), Positives = 58/96 (60%), Gaps = 2/96 (2%)
 Frame = -3

Query: 446 IRFVLLVNKQGQTRLAQCYEHLSLDERRALEGEIIRKCLARTDQ-QCSFVE-HRNYKVVY 273
           + F+L+ N+QG+TRLA+ Y   S +E+  L+GE+ R    R  + Q +FVE  R+ K+VY
Sbjct: 3   LSFILVQNRQGKTRLAKWYAPYSDEEKVKLKGEVHRLVAPRDQKYQSNFVEFKRSTKIVY 62

Query: 272 RRYASLFFLVGVDNDEASDRFCTCMLFSIFHEVLHQ 165
           RRYA LFF V VD  +    +   + F  F EVL Q
Sbjct: 63  RRYAGLFFCVCVDATDNELAYLEAIHF--FVEVLDQ 96

>AP1S3_MOUSE (Q7TN05) AP-1 complex subunit sigma-3 (Adapter-related protein|
           complex 1 sigma-1C subunit) (Sigma-adaptin 1C) (Adaptor
           protein complex AP-1 sigma-1C subunit) (Golgi adaptor
           HA1/AP1 adaptin sigma-1C subunit) (Clathrin assembly
           protein complex
          Length = 154

 Score = 60.5 bits (145), Expect = 3e-09
 Identities = 28/74 (37%), Positives = 48/74 (64%)
 Frame = -3

Query: 446 IRFVLLVNKQGQTRLAQCYEHLSLDERRALEGEIIRKCLARTDQQCSFVEHRNYKVVYRR 267
           I F+LL ++QG+ RL + Y  L   ER+ +  +II+  L+R  +  SF++ +  K+VY+R
Sbjct: 2   IHFILLFSRQGKLRLQKWYTTLPDKERKKITRDIIQTVLSRGHRTSSFIDWKELKLVYKR 61

Query: 266 YASLFFLVGVDNDE 225
           YASL+F   ++N +
Sbjct: 62  YASLYFCCAIENQD 75

>AP2S_EMENI (Q5BFF8) AP-2 complex subunit sigma (Clathrin assembly protein 2|
           small chain) (Adaptin small chain)
          Length = 145

 Score = 60.1 bits (144), Expect = 4e-09
 Identities = 40/96 (41%), Positives = 57/96 (59%), Gaps = 2/96 (2%)
 Frame = -3

Query: 446 IRFVLLVNKQGQTRLAQCYEHLSLDERRALEGEIIRKCLARTDQ-QCSFVE-HRNYKVVY 273
           + F+L+ N+QG+TRLA+ Y   S +E+  L+GE+ R    R  + Q +FVE  R+ K+VY
Sbjct: 3   LSFILVQNRQGKTRLAKWYAPYSDEEKVKLKGEVHRLVAPRDQKYQSNFVEFKRSTKIVY 62

Query: 272 RRYASLFFLVGVDNDEASDRFCTCMLFSIFHEVLHQ 165
           RRYA LFF   VD  +    +   + F  F EVL Q
Sbjct: 63  RRYAGLFFCACVDATDNELAYLEAIHF--FVEVLDQ 96

>AP1S3_HUMAN (Q96PC3) AP-1 complex subunit sigma-3 (Adapter-related protein|
           complex 1 sigma-1C subunit) (Sigma-adaptin 1C) (Adaptor
           protein complex AP-1 sigma-1C subunit) (Golgi adaptor
           HA1/AP1 adaptin sigma-1C subunit) (Clathrin assembly
           protein complex
          Length = 154

 Score = 60.1 bits (144), Expect = 4e-09
 Identities = 29/74 (39%), Positives = 48/74 (64%)
 Frame = -3

Query: 446 IRFVLLVNKQGQTRLAQCYEHLSLDERRALEGEIIRKCLARTDQQCSFVEHRNYKVVYRR 267
           I F+LL ++QG+ RL + Y  L   ER+ +  EI++  L+R  +  SFV+ +  K+VY+R
Sbjct: 2   IHFILLFSRQGKLRLQKWYITLPDKERKKITREIVQIILSRGHRTSSFVDWKELKLVYKR 61

Query: 266 YASLFFLVGVDNDE 225
           YASL+F   ++N +
Sbjct: 62  YASLYFCCAIENQD 75

>AP2S_SCHPO (Q9Y7L6) AP-2 complex subunit sigma (Clathrin assembly protein 2|
           small chain) (Adaptin small chain)
          Length = 143

 Score = 52.0 bits (123), Expect = 1e-06
 Identities = 28/75 (37%), Positives = 45/75 (60%), Gaps = 1/75 (1%)
 Frame = -3

Query: 446 IRFVLLVNKQGQTRLAQCYEHLSLDERRALEGEIIRKCLARTDQ-QCSFVEHRNYKVVYR 270
           I+F+L+ N+ G+ RL++ Y     DE+  L+  I +    R  + Q +F+E  N K+VYR
Sbjct: 2   IQFILIQNRHGKNRLSKYYVPFDDDEKVRLKARIHQLISQRNQKFQANFLEWENSKLVYR 61

Query: 269 RYASLFFLVGVDNDE 225
           RYA L+F   VD+ +
Sbjct: 62  RYAGLYFCFCVDSTD 76

>AP3S2_PONPY (Q5RDP9) AP-3 complex subunit sigma-2 (Adapter-related protein|
           complex 3 sigma-2 subunit) (Sigma-adaptin 3b) (AP-3
           complex sigma-3B subunit) (Sigma-3B-adaptin)
          Length = 193

 Score = 48.5 bits (114), Expect = 1e-05
 Identities = 25/81 (30%), Positives = 45/81 (55%), Gaps = 6/81 (7%)
 Frame = -3

Query: 446 IRFVLLVNKQGQTRLAQCYEHLSLDERRALEGEIIRKCLARTDQQCSFVEH------RNY 285
           I+ +L+ N  G+ RL + Y+    + ++ +  E     L R D  C+F+E        +Y
Sbjct: 2   IQAILVFNNHGKPRLVRFYQRFPEEIQQQIVRETFHLVLKRDDNICNFLEGGSLIGGSDY 61

Query: 284 KVVYRRYASLFFLVGVDNDEA 222
           K++YR YA+L+F+  VD+ E+
Sbjct: 62  KLIYRHYATLYFVFCVDSSES 82

>AP3S2_MOUSE (Q8BSZ2) AP-3 complex subunit sigma-2 (Adapter-related protein|
           complex 3 sigma-2 subunit) (Sigma-adaptin 3b) (AP-3
           complex sigma-3B subunit) (Sigma-3B-adaptin)
          Length = 193

 Score = 48.5 bits (114), Expect = 1e-05
 Identities = 25/81 (30%), Positives = 45/81 (55%), Gaps = 6/81 (7%)
 Frame = -3

Query: 446 IRFVLLVNKQGQTRLAQCYEHLSLDERRALEGEIIRKCLARTDQQCSFVEH------RNY 285
           I+ +L+ N  G+ RL + Y+    + ++ +  E     L R D  C+F+E        +Y
Sbjct: 2   IQAILVFNNHGKPRLVRFYQRFPEEIQQQIVRETFHLVLKRDDNICNFLEGGSLIGGSDY 61

Query: 284 KVVYRRYASLFFLVGVDNDEA 222
           K++YR YA+L+F+  VD+ E+
Sbjct: 62  KLIYRHYATLYFVFCVDSSES 82

>AP3S2_HUMAN (P59780) AP-3 complex subunit sigma-2 (Adapter-related protein|
           complex 3 sigma-2 subunit) (Sigma-adaptin 3b) (AP-3
           complex sigma-3B subunit) (Sigma-3B-adaptin)
          Length = 193

 Score = 48.5 bits (114), Expect = 1e-05
 Identities = 25/81 (30%), Positives = 45/81 (55%), Gaps = 6/81 (7%)
 Frame = -3

Query: 446 IRFVLLVNKQGQTRLAQCYEHLSLDERRALEGEIIRKCLARTDQQCSFVEH------RNY 285
           I+ +L+ N  G+ RL + Y+    + ++ +  E     L R D  C+F+E        +Y
Sbjct: 2   IQAILVFNNHGKPRLVRFYQRFPEEIQQQIVRETFHLVLKRDDNICNFLEGGSLIGGSDY 61

Query: 284 KVVYRRYASLFFLVGVDNDEA 222
           K++YR YA+L+F+  VD+ E+
Sbjct: 62  KLIYRHYATLYFVFCVDSSES 82

>AP2S_YEAST (Q00381) AP-2 complex subunit sigma (Clathrin assembly protein 2|
           small chain) (Adaptin small chain) (Clathrin coat
           assembly protein AP17) (Clathrin coat-associated protein
           AP17) (Plasma membrane adaptor AP-2 17 kDa protein)
          Length = 147

 Score = 48.5 bits (114), Expect = 1e-05
 Identities = 29/75 (38%), Positives = 48/75 (64%), Gaps = 4/75 (5%)
 Frame = -3

Query: 446 IRFVLLVNKQGQTRLAQCYEHLSLDERRALEG--EIIRKCLARTDQ-QCSFVEHRNY-KV 279
           ++F+L  NKQG  RL + ++  S D +R+ +   +I R   +R  + Q +FVE  +  K+
Sbjct: 3   VQFILCFNKQGVVRLVRWFDVHSSDPQRSQDAIAQIYRLISSRDHKHQSNFVEFSDSTKL 62

Query: 278 VYRRYASLFFLVGVD 234
           +YRRYA L+F++GVD
Sbjct: 63  IYRRYAGLYFVMGVD 77

>AP3S1_MOUSE (Q9DCR2) AP-3 complex subunit sigma-1 (Adapter-related protein|
           complex 3 sigma-1 subunit) (Sigma-adaptin 3a) (AP-3
           complex sigma-3A subunit) (Sigma-3A-adaptin)
          Length = 193

 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 24/81 (29%), Positives = 45/81 (55%), Gaps = 6/81 (7%)
 Frame = -3

Query: 446 IRFVLLVNKQGQTRLAQCYEHLSLDERRALEGEIIRKCLARTDQQCSFVEH------RNY 285
           I+ +L+ N  G+ RL++ Y+  S D ++ +  E       R +  C+F+E        + 
Sbjct: 2   IKAILIFNNHGKPRLSKFYQPYSEDTQQQIIRETFHLVSKRDENVCNFLEGGLLIGGSDN 61

Query: 284 KVVYRRYASLFFLVGVDNDEA 222
           K++YR YA+L+F+  VD+ E+
Sbjct: 62  KLIYRHYATLYFVFCVDSSES 82

>AP3S1_HUMAN (Q92572) AP-3 complex subunit sigma-1 (Adapter-related protein|
           complex 3 sigma-1 subunit) (Sigma-adaptin 3a) (AP-3
           complex sigma-3A subunit) (Sigma-3A-adaptin)
           (Clathrin-associated/assembly/adapter protein, small 3)
          Length = 193

 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 24/81 (29%), Positives = 45/81 (55%), Gaps = 6/81 (7%)
 Frame = -3

Query: 446 IRFVLLVNKQGQTRLAQCYEHLSLDERRALEGEIIRKCLARTDQQCSFVEH------RNY 285
           I+ +L+ N  G+ RL++ Y+  S D ++ +  E       R +  C+F+E        + 
Sbjct: 2   IKAILIFNNHGKPRLSKFYQPYSEDTQQQIIRETFHLVSKRDENVCNFLEGGLLIGGSDN 61

Query: 284 KVVYRRYASLFFLVGVDNDEA 222
           K++YR YA+L+F+  VD+ E+
Sbjct: 62  KLIYRHYATLYFVFCVDSSES 82

>AP3S_SCHPO (Q09905) AP-3 complex subunit sigma (Adapter-related protein|
           complex 3 sigma subunit) (Sigma-adaptin 3A) (AP-3
           complex sigma3A subunit) (Sigma-adaptin)
           (Clathrin-associated/assembly/adapter protein, small 3)
          Length = 165

 Score = 42.0 bits (97), Expect = 0.001
 Identities = 22/76 (28%), Positives = 40/76 (52%), Gaps = 4/76 (5%)
 Frame = -3

Query: 437 VLLVNKQGQTRLAQCYEHLSLDERRALEGEIIRKCLARTDQQCSFVEHR----NYKVVYR 270
           V + N +G+ RL + Y  +    ++ L G+I      R    C+F+E        +++YR
Sbjct: 5   VFIFNNKGKPRLTKFYTPIDESIQQKLIGDIYAAVSTRPPTACNFLESNLIAGKNRIIYR 64

Query: 269 RYASLFFLVGVDNDEA 222
           +YA+L+F+  VD  E+
Sbjct: 65  QYATLYFVFVVDEGES 80

>AP3S_YEAST (P47064) AP-3 complex subunit sigma (Adapter-related protein|
           complex 3 sigma subunit) (Sigma-adaptin 3A) (AP-3
           complex sigma3A subunit) (Sigma-adaptin)
           (Clathrin-associated/assembly/adapter protein, small 3)
          Length = 194

 Score = 35.8 bits (81), Expect = 0.086
 Identities = 39/147 (26%), Positives = 61/147 (41%), Gaps = 23/147 (15%)
 Frame = -3

Query: 446 IRFVLLVNKQGQTRLAQCYEHLSLDERRALEGEIIRKCLAR-TDQQCSF----------- 303
           I  VL+ NK+ Q RL + Y  + L +++ L  ++      R +D Q SF           
Sbjct: 2   IHAVLIFNKKCQPRLVKFYTPVDLPKQKLLLEQVYELISQRNSDFQSSFLVTPPSLLLSN 61

Query: 302 ------VEHRNYKVVYRRYASLFFLVGVDNDEASDRFCTCMLFSIFHEVLHQITFTSREA 141
                 V + + +++Y+ YA+L+F   VD+ E+        L   F E L +      E 
Sbjct: 62  ENNNDEVNNEDIQIIYKNYATLYFTFIVDDQES--ELAILDLIQTFVESLDRCFTEVNEL 119

Query: 140 -----WQILMKCLKMISCNMGCIETIV 75
                WQ L   L+ I      IET V
Sbjct: 120 DLIFNWQTLESVLEEIVQGGMVIETNV 146

>CSN10_CANGA (Q6FVG5) COP9 signalosome complex subunit 10|
          Length = 643

 Score = 35.0 bits (79), Expect = 0.15
 Identities = 28/104 (26%), Positives = 47/104 (45%), Gaps = 12/104 (11%)
 Frame = -3

Query: 404 LAQCYEHLSLDERRAL--EGEIIRKCLARTDQQCS---FVEHRNYKVVYRRYASLFFLV- 243
           + QCY    ++++  L  EGE+ R CL + DQ+C+    V  R+   +   ++   FL+ 
Sbjct: 236 ILQCYIARYIEDQHLLCNEGEVFRMCLNQLDQKCNESLAVAQRSDINLILHFSKALFLIL 295

Query: 242 -GVDNDEASD----RFCTCM-LFSIFHEVLHQITFTSREAWQIL 129
             +D D+  D       TC+  F   H+    I     E W+ L
Sbjct: 296 FELDQDDLGDGNKVTGSTCVRRFVTIHKFYQNIECCKEEFWECL 339

>AP3S_ASHGO (Q75F71) AP-3 complex subunit sigma (Adapter-related protein|
           complex 3 sigma subunit) (Sigma-adaptin 3A) (AP-3
           complex sigma3A subunit) (Sigma-adaptin)
           (Clathrin-associated/assembly/adapter protein, small 3)
          Length = 185

 Score = 34.3 bits (77), Expect = 0.25
 Identities = 37/143 (25%), Positives = 59/143 (41%), Gaps = 19/143 (13%)
 Frame = -3

Query: 446 IRFVLLVNKQGQTRLAQCYEHLSLDERRALEGEIIRKCLARTDQ-QCSFVE--------- 297
           I  VL+ NK+ Q RL + Y  + L +++ L  ++      R    Q SF+          
Sbjct: 2   IHAVLIFNKKCQPRLVKYYTPVDLPKQKLLLEQVYELISQRNSSIQSSFLITPPSLLSSG 61

Query: 296 ----HRNYKVVYRRYASLFFLVGVDNDEASDRFCTCMLFSIFHEVLHQITFTSREA---- 141
               + + +++Y+ YA+L+F   VD+ E+        L   F E L +      E     
Sbjct: 62  SETINEDIQIIYKNYATLYFTFIVDDQES--ELAILDLIQTFVEALDRCFAEVNELDLIF 119

Query: 140 -WQILMKCLKMISCNMGCIETIV 75
            WQ L   L+ I      IET V
Sbjct: 120 NWQTLESVLEEIIQGGMVIETNV 142

>LIT_ECOLI (P11072) Bacteriophage T4 late gene expression-blocking protein|
           (GpLit)
          Length = 297

 Score = 30.0 bits (66), Expect = 4.7
 Identities = 20/75 (26%), Positives = 29/75 (38%)
 Frame = -3

Query: 404 LAQCYEHLSLDERRALEGEIIRKCLARTDQQCSFVEHRNYKVVYRRYASLFFLVGVDNDE 225
           L   YE     ++RAL       C+   + +  F     +   Y R  S      V N+E
Sbjct: 193 LGNLYESAPELKKRALGIATAVLCIQSLEVENYFCLQNTHPAAYERIYSNISCYPVGNEE 252

Query: 224 ASDRFCTCMLFSIFH 180
             +  CT ML  +FH
Sbjct: 253 LIEALCTVMLQYLFH 267

>PCF11_YEAST (P39081) Protein PCF11 (protein 1 of CF I)|
          Length = 626

 Score = 30.0 bits (66), Expect = 4.7
 Identities = 20/68 (29%), Positives = 32/68 (47%), Gaps = 5/68 (7%)
 Frame = +3

Query: 78  NSFNTTHVTRNHLQAFHQYLP-----SFP*SEGNLMQYLMEYGEEHAGAEPVGRLIVVHA 242
           NS   T  TR ++Q+ + YL      +F   E    ++  +Y + HA        + +HA
Sbjct: 465 NSNLNTTTTRKNIQSRNWYLSDSQWAAFKDDEITSTKHKNDYTDPHANKNIDKSALNIHA 524

Query: 243 DEEEEGGV 266
           DE +EG V
Sbjct: 525 DENDEGSV 532

>DREB_HUMAN (Q16643) Drebrin (Developmentally-regulated brain protein)|
          Length = 648

 Score = 29.3 bits (64), Expect = 8.0
 Identities = 15/31 (48%), Positives = 19/31 (61%), Gaps = 3/31 (9%)
 Frame = +3

Query: 372 VEGEVLVALRQPRLPLLVH---QQHEPDPHL 455
           VEGE L A + P LP  +    Q+ EP+PHL
Sbjct: 548 VEGEPLAAPQTPTLPSALEELEQEQEPEPHL 578


  Database: uniprot_sprot.fasta
    Posted date:  May 25, 2006  5:36 PM
  Number of letters in database: 80,573,946
  Number of sequences in database:  219,361
  
Lambda     K      H
   0.318    0.135    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 60,990,158
Number of Sequences: 219361
Number of extensions: 1035038
Number of successful extensions: 3175
Number of sequences better than 10.0: 32
Number of HSP's better than 10.0 without gapping: 3120
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3167
length of database: 80,573,946
effective HSP length: 106
effective length of database: 57,321,680
effective search space used: 4643056080
frameshift window, decay const: 50,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)