ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
menu 
| Clone Name | rbasd3p09 |
|---|---|
| Clone Library Name | barley_pub |
>ARHG6_CHICK (Q5ZLR6) Rho guanine nucleotide exchange factor 6 (Rac/Cdc42| guanine nucleotide exchange factor 6) Length = 764 Score = 51.2 bits (121), Expect = 1e-06 Identities = 21/45 (46%), Positives = 29/45 (64%) Frame = -1 Query: 407 SFKXESEFELNLSVGDIVIVRKISSNGWAEGECKGKAGWFPHAYV 273 +FK +E EL+++ GDI+ V ++ GW EG GK GWFP YV Sbjct: 162 NFKQTNEDELSVNKGDIIYVTRVEEGGWWEGTLNGKTGWFPSNYV 206
>ARHG6_MOUSE (Q8K4I3) Rho guanine nucleotide exchange factor 6 (Rac/Cdc42| guanine nucleotide exchange factor 6) Length = 771 Score = 50.1 bits (118), Expect = 2e-06 Identities = 24/58 (41%), Positives = 33/58 (56%), Gaps = 3/58 (5%) Frame = -1 Query: 407 SFKXESEFELNLSVGDIVIVRKISSNGWAEGECKGKAGWFPHAYVER---RERVLASK 243 +FK +E EL++ GDI+ V ++ GW EG G+ GWFP YV ER L+ K Sbjct: 169 NFKQTNEDELSVCKGDIIYVTRVEEGGWWEGTLNGRTGWFPSNYVREIKPSERPLSPK 226
>ARHG6_RAT (Q5XXR3) Rho guanine nucleotide exchange factor 6 (Rac/Cdc42| guanine nucleotide exchange factor 6) Length = 772 Score = 50.1 bits (118), Expect = 2e-06 Identities = 24/58 (41%), Positives = 33/58 (56%), Gaps = 3/58 (5%) Frame = -1 Query: 407 SFKXESEFELNLSVGDIVIVRKISSNGWAEGECKGKAGWFPHAYVER---RERVLASK 243 +FK +E EL++ GDI+ V ++ GW EG G+ GWFP YV ER L+ K Sbjct: 170 NFKQTNEDELSVCKGDIIYVTRVEEGGWWEGTLNGRTGWFPSNYVREIKPSERPLSPK 227
>ARHG6_HUMAN (Q15052) Rho guanine nucleotide exchange factor 6 (Rac/Cdc42| guanine nucleotide exchange factor 6) (PAK-interacting exchange factor alpha) (Alpha-Pix) (COOL-2) Length = 776 Score = 50.1 bits (118), Expect = 2e-06 Identities = 24/58 (41%), Positives = 34/58 (58%), Gaps = 3/58 (5%) Frame = -1 Query: 407 SFKXESEFELNLSVGDIVIVRKISSNGWAEGECKGKAGWFPHAYV---ERRERVLASK 243 +FK +E EL++ GDI+ V ++ GW EG G+ GWFP YV + ER L+ K Sbjct: 170 NFKQTNEDELSVCKGDIIYVTRVEEGGWWEGTLNGRTGWFPSNYVREIKSSERPLSPK 227
>VAV3_HUMAN (Q9UKW4) Protein vav-3| Length = 847 Score = 49.3 bits (116), Expect = 4e-06 Identities = 23/42 (54%), Positives = 28/42 (66%), Gaps = 1/42 (2%) Frame = -1 Query: 383 ELNLSVGDIV-IVRKISSNGWAEGECKGKAGWFPHAYVERRE 261 EL+L GD+V I K+S+NGW GE G+ GWFP YVE E Sbjct: 806 ELSLLKGDVVKIYTKMSANGWWRGEVNGRVGWFPSTYVEEDE 847
>ARHG7_HUMAN (Q14155) Rho guanine nucleotide exchange factor 7 (PAK-interacting| exchange factor beta) (Beta-Pix) (COOL-1) (p85) Length = 803 Score = 48.9 bits (115), Expect = 5e-06 Identities = 23/57 (40%), Positives = 33/57 (57%) Frame = -1 Query: 407 SFKXESEFELNLSVGDIVIVRKISSNGWAEGECKGKAGWFPHAYVERRERVLASKVP 237 +F+ +E EL+ S GD++ V ++ GW EG G+ GWFP YV V AS+ P Sbjct: 194 NFQQTNEDELSFSKGDVIHVTRVEEGGWWEGTLNGRTGWFPSNYV---REVKASEKP 247
>VAV3_MOUSE (Q9R0C8) Protein vav-3| Length = 847 Score = 48.5 bits (114), Expect = 7e-06 Identities = 23/42 (54%), Positives = 28/42 (66%), Gaps = 1/42 (2%) Frame = -1 Query: 383 ELNLSVGDIV-IVRKISSNGWAEGECKGKAGWFPHAYVERRE 261 EL+L GD+V I K+S+NGW GE G+ GWFP YVE E Sbjct: 806 ELSLLKGDMVKIYTKMSANGWWRGEVNGRVGWFPSTYVEEDE 847
>NCF2_HUMAN (P19878) Neutrophil cytosol factor 2 (NCF-2) (Neutrophil NADPH| oxidase factor 2) (67 kDa neutrophil oxidase factor) (p67-phox) (NOXA2) Length = 526 Score = 47.8 bits (112), Expect = 1e-05 Identities = 22/50 (44%), Positives = 29/50 (58%) Frame = -1 Query: 419 EALDSFKXESEFELNLSVGDIVIVRKISSNGWAEGECKGKAGWFPHAYVE 270 EAL S++ +L GDI++V + W EGECKGK G FP +VE Sbjct: 463 EALFSYEATQPEDLEFQEGDIILVLSKVNEEWLEGECKGKVGIFPKVFVE 512 Score = 30.4 bits (67), Expect = 1.9 Identities = 20/54 (37%), Positives = 28/54 (51%), Gaps = 3/54 (5%) Frame = -1 Query: 422 GEA---LDSFKXESEFELNLSVGDIVIVRKISSNGWAEGECKGKAGWFPHAYVE 270 GEA L F E++ EL + G+IV V K ++ WA G+ G P Y+E Sbjct: 242 GEAHRVLFGFVPETKEELQVMPGNIVFVLKKGNDNWATVMFNGQKGLVPCNYLE 295
>ARHG7_RAT (O55043) Rho guanine nucleotide exchange factor 7 (PAK-interacting| exchange factor beta) (Beta-Pix) Length = 646 Score = 47.4 bits (111), Expect = 2e-05 Identities = 19/45 (42%), Positives = 28/45 (62%) Frame = -1 Query: 407 SFKXESEFELNLSVGDIVIVRKISSNGWAEGECKGKAGWFPHAYV 273 +F+ +E EL+ S GD++ V ++ GW EG G+ GWFP YV Sbjct: 16 NFQQTNEDELSFSKGDVIHVTRVEEGGWWEGTHNGRTGWFPSNYV 60
>ARHG7_MOUSE (Q9ES28) Rho guanine nucleotide exchange factor 7 (PAK-interacting| exchange factor beta) (Beta-Pix) (p85SPR) Length = 705 Score = 47.4 bits (111), Expect = 2e-05 Identities = 19/45 (42%), Positives = 28/45 (62%) Frame = -1 Query: 407 SFKXESEFELNLSVGDIVIVRKISSNGWAEGECKGKAGWFPHAYV 273 +F+ +E EL+ S GD++ V ++ GW EG G+ GWFP YV Sbjct: 16 NFQQTNEDELSFSKGDVIHVTRVEEGGWWEGTHNGRTGWFPSNYV 60
>NCF2_BOVIN (O77775) Neutrophil cytosol factor 2 (NCF-2) (Neutrophil NADPH| oxidase factor 2) (67 kDa neutrophil oxidase factor) (p67-phox) Length = 527 Score = 47.0 bits (110), Expect = 2e-05 Identities = 21/50 (42%), Positives = 30/50 (60%) Frame = -1 Query: 416 ALDSFKXESEFELNLSVGDIVIVRKISSNGWAEGECKGKAGWFPHAYVER 267 AL S++ +L GD+++V + W EGECKGK G FP A+VE+ Sbjct: 465 ALFSYEATQPEDLEFLEGDVILVISTVNEQWLEGECKGKVGIFPKAFVEQ 514 Score = 29.6 bits (65), Expect = 3.3 Identities = 20/54 (37%), Positives = 27/54 (50%), Gaps = 3/54 (5%) Frame = -1 Query: 422 GEA---LDSFKXESEFELNLSVGDIVIVRKISSNGWAEGECKGKAGWFPHAYVE 270 GEA L F E+ EL + G+IV V K ++ WA G+ G P Y+E Sbjct: 242 GEAHRVLFGFVPETPEELQVMPGNIVFVLKKGNDNWATVMFNGQKGLVPCNYLE 295
>ITSN1_XENLA (O42287) Intersectin-1| Length = 1270 Score = 46.6 bits (109), Expect = 3e-05 Identities = 23/52 (44%), Positives = 29/52 (55%), Gaps = 2/52 (3%) Frame = -1 Query: 416 ALDSFKXESEFELNLSVGDIVIVRKISSN--GWAEGECKGKAGWFPHAYVER 267 AL F S E+ + GDI++V + + GW GE KGK GWFP Y ER Sbjct: 739 ALYPFDARSHDEITIEPGDIIMVDESQTGEPGWLGGELKGKTGWFPANYAER 790 Score = 40.0 bits (92), Expect = 0.002 Identities = 18/57 (31%), Positives = 32/57 (56%), Gaps = 5/57 (8%) Frame = -1 Query: 425 LGEALDSFKXESEFELNLSVGDIVIVRKISSNGWAEGEC-----KGKAGWFPHAYVE 270 + + + S+ + +L L+ G ++++RK + GW EGE K + GWFP YV+ Sbjct: 1062 IAQVIASYAATAPEQLTLAPGQLILIRKKNPGGWWEGELQARGKKRQIGWFPANYVK 1118 Score = 36.2 bits (82), Expect = 0.035 Identities = 16/50 (32%), Positives = 30/50 (60%) Frame = -1 Query: 419 EALDSFKXESEFELNLSVGDIVIVRKISSNGWAEGECKGKAGWFPHAYVE 270 +AL ++ + + LN + D++ V + + W GE +G+ GWFP +YV+ Sbjct: 903 QALYPWRAKKDNHLNFNKNDVITVLE-QQDMWWFGEVQGQKGWFPKSYVK 951 Score = 30.0 bits (66), Expect = 2.5 Identities = 14/42 (33%), Positives = 21/42 (50%) Frame = -1 Query: 395 ESEFELNLSVGDIVIVRKISSNGWAEGECKGKAGWFPHAYVE 270 +++ EL S G ++ V W +GE G G FP YV+ Sbjct: 1153 QNDDELAFSKGQVINVLNKEDPDWWKGELNGHVGLFPSNYVK 1194
>ITSN1_MOUSE (Q9Z0R4) Intersectin-1 (EH and SH3 domains protein 1)| Length = 1714 Score = 46.6 bits (109), Expect = 3e-05 Identities = 23/52 (44%), Positives = 30/52 (57%), Gaps = 2/52 (3%) Frame = -1 Query: 416 ALDSFKXESEFELNLSVGDIVIVRKISSN--GWAEGECKGKAGWFPHAYVER 267 AL F+ S E+ + GDIV+V + + GW GE KGK GWFP Y E+ Sbjct: 745 ALYPFESRSHDEITIQPGDIVMVDESQTGEPGWLGGELKGKTGWFPANYAEK 796 Score = 39.7 bits (91), Expect = 0.003 Identities = 18/57 (31%), Positives = 31/57 (54%), Gaps = 5/57 (8%) Frame = -1 Query: 425 LGEALDSFKXESEFELNLSVGDIVIVRKISSNGWAEGEC-----KGKAGWFPHAYVE 270 + + + S+ +L L+ G ++++RK + GW EGE K + GWFP YV+ Sbjct: 1071 IAQVIASYAATGPEQLTLAPGQLILIRKKNPGGWWEGELQARGKKRQIGWFPANYVK 1127 Score = 36.2 bits (82), Expect = 0.035 Identities = 16/50 (32%), Positives = 30/50 (60%) Frame = -1 Query: 419 EALDSFKXESEFELNLSVGDIVIVRKISSNGWAEGECKGKAGWFPHAYVE 270 +AL ++ + + LN + D++ V + + W GE +G+ GWFP +YV+ Sbjct: 912 QALYPWRAKKDNHLNFNKSDVITVLE-QQDMWWFGEVQGQKGWFPKSYVK 960 Score = 32.0 bits (71), Expect = 0.67 Identities = 15/45 (33%), Positives = 23/45 (51%) Frame = -1 Query: 404 FKXESEFELNLSVGDIVIVRKISSNGWAEGECKGKAGWFPHAYVE 270 + +++ EL S G I+ V W +GE G+ G FP YV+ Sbjct: 1159 YTAQNDDELAFSKGQIINVLNKEDPDWWKGEVSGQVGLFPSNYVK 1203 Score = 30.8 bits (68), Expect = 1.5 Identities = 14/52 (26%), Positives = 27/52 (51%) Frame = -1 Query: 416 ALDSFKXESEFELNLSVGDIVIVRKISSNGWAEGECKGKAGWFPHAYVERRE 261 A+ +++ + +L GD+++V K + W G K+G FP YV ++ Sbjct: 1002 AMYTYESSEQGDLTFQQGDVIVVTKKDGDWWT-GTVGDKSGVFPSNYVRLKD 1052
>ITSN1_HUMAN (Q15811) Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17)| Length = 1721 Score = 45.4 bits (106), Expect = 6e-05 Identities = 23/57 (40%), Positives = 30/57 (52%), Gaps = 7/57 (12%) Frame = -1 Query: 416 ALDSFKXESEFELNLSVGDIVIVR-------KISSNGWAEGECKGKAGWFPHAYVER 267 AL F+ S E+ + GDIV+V+ + GW GE KGK GWFP Y E+ Sbjct: 747 ALYPFESRSHDEITIQPGDIVMVKGEWVDESQTGEPGWLGGELKGKTGWFPANYAEK 803 Score = 39.7 bits (91), Expect = 0.003 Identities = 18/57 (31%), Positives = 31/57 (54%), Gaps = 5/57 (8%) Frame = -1 Query: 425 LGEALDSFKXESEFELNLSVGDIVIVRKISSNGWAEGEC-----KGKAGWFPHAYVE 270 + + + S+ +L L+ G ++++RK + GW EGE K + GWFP YV+ Sbjct: 1078 IAQVIASYTATGPEQLTLAPGQLILIRKKNPGGWWEGELQARGKKRQIGWFPANYVK 1134 Score = 36.2 bits (82), Expect = 0.035 Identities = 16/50 (32%), Positives = 30/50 (60%) Frame = -1 Query: 419 EALDSFKXESEFELNLSVGDIVIVRKISSNGWAEGECKGKAGWFPHAYVE 270 +AL ++ + + LN + D++ V + + W GE +G+ GWFP +YV+ Sbjct: 919 QALYPWRAKKDNHLNFNKNDVITVLE-QQDMWWFGEVQGQKGWFPKSYVK 967 Score = 31.6 bits (70), Expect = 0.87 Identities = 15/52 (28%), Positives = 27/52 (51%) Frame = -1 Query: 416 ALDSFKXESEFELNLSVGDIVIVRKISSNGWAEGECKGKAGWFPHAYVERRE 261 A+ +++ + +L GD+++V K + W G KAG FP YV ++ Sbjct: 1009 AMYTYESSEQGDLTFQQGDVILVTKKDGDWWT-GTVGDKAGVFPSNYVRLKD 1059 Score = 30.8 bits (68), Expect = 1.5 Identities = 14/45 (31%), Positives = 23/45 (51%) Frame = -1 Query: 404 FKXESEFELNLSVGDIVIVRKISSNGWAEGECKGKAGWFPHAYVE 270 + +++ EL + G I+ V W +GE G+ G FP YV+ Sbjct: 1166 YTAQNDDELAFNKGQIINVLNKEDPDWWKGEVNGQVGLFPSNYVK 1210
>ITSN1_RAT (Q9WVE9) Intersectin-1 (EH domain and SH3 domain regulator of| endocytosis 1) Length = 1217 Score = 44.7 bits (104), Expect = 1e-04 Identities = 23/57 (40%), Positives = 30/57 (52%), Gaps = 7/57 (12%) Frame = -1 Query: 416 ALDSFKXESEFELNLSVGDIVIVR-------KISSNGWAEGECKGKAGWFPHAYVER 267 AL F+ S E+ + GDIV+V+ + GW GE KGK GWFP Y E+ Sbjct: 744 ALYPFESRSHDEITIQPGDIVMVKGEWVDESQTGEPGWLGGEPKGKTGWFPANYAEK 800 Score = 39.7 bits (91), Expect = 0.003 Identities = 18/57 (31%), Positives = 31/57 (54%), Gaps = 5/57 (8%) Frame = -1 Query: 425 LGEALDSFKXESEFELNLSVGDIVIVRKISSNGWAEGEC-----KGKAGWFPHAYVE 270 + + + S+ +L L+ G ++++RK + GW EGE K + GWFP YV+ Sbjct: 1075 IAQVIASYTATGPEQLTLAPGQLILIRKKNPGGWWEGELQARGKKRQIGWFPANYVK 1131 Score = 36.2 bits (82), Expect = 0.035 Identities = 16/50 (32%), Positives = 30/50 (60%) Frame = -1 Query: 419 EALDSFKXESEFELNLSVGDIVIVRKISSNGWAEGECKGKAGWFPHAYVE 270 +AL ++ + + LN + D++ V + + W GE +G+ GWFP +YV+ Sbjct: 916 QALYPWRAKKDNHLNFNKSDVITVLE-QQDMWWFGEVQGQKGWFPKSYVK 964 Score = 32.0 bits (71), Expect = 0.67 Identities = 15/45 (33%), Positives = 23/45 (51%) Frame = -1 Query: 404 FKXESEFELNLSVGDIVIVRKISSNGWAEGECKGKAGWFPHAYVE 270 + +++ EL S G I+ V W +GE G+ G FP YV+ Sbjct: 1163 YTAQNDDELAFSKGQIINVLSKEDPDWWKGEVSGQVGLFPSNYVK 1207
>SHAN1_HUMAN (Q9Y566) SH3 and multiple ankyrin repeat domains protein 1 (Shank1)| (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP) Length = 2161 Score = 43.9 bits (102), Expect = 2e-04 Identities = 19/49 (38%), Positives = 32/49 (65%) Frame = -1 Query: 416 ALDSFKXESEFELNLSVGDIVIVRKISSNGWAEGECKGKAGWFPHAYVE 270 A+ S++ ++E E++LS G+ + V I G+ EG+ KG+ GWFP +E Sbjct: 561 AVKSYQAQAEGEISLSKGEKIKVLSIGEGGFWEGQVKGRVGWFPSDCLE 609
>MYSB_ACACA (P19706) Myosin heavy chain IB (Myosin heavy chain IL)| Length = 1147 Score = 43.5 bits (101), Expect = 2e-04 Identities = 20/50 (40%), Positives = 27/50 (54%) Frame = -1 Query: 419 EALDSFKXESEFELNLSVGDIVIVRKISSNGWAEGECKGKAGWFPHAYVE 270 +AL + ++ EL GD +IV + GW EGE GK GW P YV+ Sbjct: 1096 KALYDYDAQTGDELTFKEGDTIIVHQKDPAGWWEGELNGKRGWVPANYVQ 1145
>SHAN1_RAT (Q9WV48) SH3 and multiple ankyrin repeat domains protein 1 (Shank1)| (GKAP/SAPAP-interacting protein) (SPANK-1) (Synamon) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP) Length = 2167 Score = 43.5 bits (101), Expect = 2e-04 Identities = 19/49 (38%), Positives = 31/49 (63%) Frame = -1 Query: 416 ALDSFKXESEFELNLSVGDIVIVRKISSNGWAEGECKGKAGWFPHAYVE 270 A+ S++ + E E++LS G+ + V I G+ EG+ KG+ GWFP +E Sbjct: 561 AVKSYQAQGEGEISLSKGEKIKVLSIGEGGFWEGQVKGRVGWFPSDCLE 609
>VINEX_MOUSE (Q9R1Z8) Vinexin (Sorbin and SH3 domain-containing protein 3)| (SH3-containing adapter molecule 1) (SCAM-1) (SH3 domain-containing protein SH3P3) Length = 733 Score = 43.1 bits (100), Expect = 3e-04 Identities = 21/45 (46%), Positives = 26/45 (57%) Frame = -1 Query: 404 FKXESEFELNLSVGDIVIVRKISSNGWAEGECKGKAGWFPHAYVE 270 F+ +S EL+L GDIV + K W EGE G+ G FP YVE Sbjct: 455 FQAQSPKELSLQKGDIVYIHKEVDKNWLEGEHHGRLGIFPANYVE 499 Score = 31.2 bits (69), Expect = 1.1 Identities = 18/49 (36%), Positives = 30/49 (61%), Gaps = 3/49 (6%) Frame = -1 Query: 407 SFKXESEFELNLSVGD-IVIVRKISSNGWAEGEC--KGKAGWFPHAYVE 270 +FK + E EL+ G+ I ++RK++ + W EG G+ G FP +YV+ Sbjct: 528 TFKGDLEVELSFRKGERICLIRKVNEH-WYEGRITGTGRQGIFPASYVQ 575
>ITSN2_MOUSE (Q9Z0R6) Intersectin-2 (SH3 domain-containing protein 1B) (EH and| SH3 domains protein 2) (EH domain and SH3 domain regulator of endocytosis 2) Length = 1658 Score = 43.1 bits (100), Expect = 3e-04 Identities = 24/63 (38%), Positives = 35/63 (55%), Gaps = 5/63 (7%) Frame = -1 Query: 416 ALDSFKXESEFELNLSVGDIVIV--RKISSNGWAEGECKGKAGWFPHAYVER---RERVL 252 AL F+ + E++ S GDI+ V + + GW G +GK GWFP YVE+ E+ L Sbjct: 724 ALYPFEARNHDEMSFSSGDIIQVDEKTVGEPGWLYGSFQGKFGWFPCNYVEKVLSSEKAL 783 Query: 251 ASK 243 + K Sbjct: 784 SPK 786 Score = 39.3 bits (90), Expect = 0.004 Identities = 20/50 (40%), Positives = 28/50 (56%) Frame = -1 Query: 419 EALDSFKXESEFELNLSVGDIVIVRKISSNGWAEGECKGKAGWFPHAYVE 270 +AL S+ + E LN S D++ V + N W GE G GWFP +YV+ Sbjct: 857 QALCSWTAKKENHLNFSKHDVITVLEQQENWWF-GEVHGGRGWFPKSYVK 905 Score = 35.4 bits (80), Expect = 0.061 Identities = 17/49 (34%), Positives = 24/49 (48%) Frame = -1 Query: 416 ALDSFKXESEFELNLSVGDIVIVRKISSNGWAEGECKGKAGWFPHAYVE 270 A+ + +E ELN S G ++ V W +GE G G FP YV+ Sbjct: 1094 AMYDYMANNEDELNFSKGQLINVMNKDDPDWWQGETNGLTGLFPSNYVK 1142 Score = 35.4 bits (80), Expect = 0.061 Identities = 14/57 (24%), Positives = 33/57 (57%), Gaps = 5/57 (8%) Frame = -1 Query: 425 LGEALDSFKXESEFELNLSVGDIVIVRKISSNGWAEGEC-----KGKAGWFPHAYVE 270 + + ++ +L+L+ G ++++ K +++GW +GE K + GWFP ++V+ Sbjct: 1017 IAQVTSAYAASGTEQLSLAPGQLILILKKNTSGWWQGELQARGKKRQKGWFPASHVK 1073
>STE6_SCHPO (P26674) Protein ste6| Length = 911 Score = 42.7 bits (99), Expect = 4e-04 Identities = 19/54 (35%), Positives = 30/54 (55%) Frame = -1 Query: 380 LNLSVGDIVIVRKISSNGWAEGECKGKAGWFPHAYVERRERVLASKVPHIF*GF 219 L S GD +IV ++ +GW +G C K GWFP + ++ +SK+ + F F Sbjct: 20 LKFSAGDTIIVIEVLEDGWCDGICSEKRGWFPTSCID------SSKIQNFFSSF 67
>VINEX_HUMAN (O60504) Vinexin (Sorbin and SH3 domain-containing protein 3)| (SH3-containing adapter molecule 1) (SCAM-1) Length = 671 Score = 42.7 bits (99), Expect = 4e-04 Identities = 21/45 (46%), Positives = 25/45 (55%) Frame = -1 Query: 404 FKXESEFELNLSVGDIVIVRKISSNGWAEGECKGKAGWFPHAYVE 270 F+ +S EL L GDIV + K W EGE G+ G FP YVE Sbjct: 391 FQAQSPKELTLQKGDIVYIHKEVDKNWLEGEHHGRLGIFPANYVE 435 Score = 33.5 bits (75), Expect = 0.23 Identities = 22/56 (39%), Positives = 34/56 (60%), Gaps = 5/56 (8%) Frame = -1 Query: 422 GEALD--SFKXESEFELNLSVGD-IVIVRKISSNGWAEGEC--KGKAGWFPHAYVE 270 GEA+ +FK + E EL+ G+ I ++RK++ N W EG G+ G FP +YV+ Sbjct: 457 GEAVAQYTFKGDLEVELSFRKGEHICLIRKVNEN-WYEGRITGTGRQGIFPASYVQ 511
>VAV_MOUSE (P27870) Proto-oncogene vav (p95vav)| Length = 845 Score = 42.7 bits (99), Expect = 4e-04 Identities = 21/46 (45%), Positives = 25/46 (54%), Gaps = 1/46 (2%) Frame = -1 Query: 404 FKXESEFELNLSVGDIV-IVRKISSNGWAEGECKGKAGWFPHAYVE 270 F EL+L GDI+ I+ K GW GE G+ GWFP YVE Sbjct: 793 FCARDRSELSLKEGDIIKILNKKGQQGWWRGEIYGRIGWFPSNYVE 838
>VAV_HUMAN (P15498) Proto-oncogene vav| Length = 845 Score = 42.7 bits (99), Expect = 4e-04 Identities = 21/46 (45%), Positives = 25/46 (54%), Gaps = 1/46 (2%) Frame = -1 Query: 404 FKXESEFELNLSVGDIV-IVRKISSNGWAEGECKGKAGWFPHAYVE 270 F EL+L GDI+ I+ K GW GE G+ GWFP YVE Sbjct: 793 FCARDRSELSLKEGDIIKILNKKGQQGWWRGEIYGRVGWFPANYVE 838
>VAV_RAT (P54100) Proto-oncogene vav (p95)| Length = 843 Score = 42.7 bits (99), Expect = 4e-04 Identities = 21/46 (45%), Positives = 25/46 (54%), Gaps = 1/46 (2%) Frame = -1 Query: 404 FKXESEFELNLSVGDIV-IVRKISSNGWAEGECKGKAGWFPHAYVE 270 F EL+L GDI+ I+ K GW GE G+ GWFP YVE Sbjct: 791 FCARDRSELSLKEGDIIKILNKKGQQGWWRGEIYGRIGWFPSNYVE 836
>SRBS1_HUMAN (Q9BX66) Sorbin and SH3 domain-containing protein 1 (Ponsin)| (c-Cbl-associated protein) (CAP) (SH3 domain protein 5) (SH3P12) Length = 1292 Score = 42.0 bits (97), Expect = 6e-04 Identities = 20/45 (44%), Positives = 25/45 (55%) Frame = -1 Query: 404 FKXESEFELNLSVGDIVIVRKISSNGWAEGECKGKAGWFPHAYVE 270 FK ++ EL L GDIV + K W EGE G+ G FP Y+E Sbjct: 804 FKAQTLKELPLQKGDIVYIYKQIDQNWYEGEHHGRVGIFPRTYIE 848 Score = 34.3 bits (77), Expect = 0.13 Identities = 22/57 (38%), Positives = 32/57 (56%), Gaps = 2/57 (3%) Frame = -1 Query: 434 DLFLGEALDSFKXESEFELNLSVGDIVIVRKISSNGWAEGECK--GKAGWFPHAYVE 270 DLF +AL S+ +++ EL L GDIV V + +GW G + + G FP YV+ Sbjct: 1232 DLFSYQALYSYIPQNDDELELRDGDIVDVMEKCDDGWFVGTSRRTKQFGTFPGNYVK 1288
>NCK1_HUMAN (P16333) Cytoplasmic protein NCK1 (NCK adaptor protein 1) (SH2/SH3| adaptor protein NCK-alpha) Length = 377 Score = 42.0 bits (97), Expect = 6e-04 Identities = 20/45 (44%), Positives = 26/45 (57%) Frame = -1 Query: 407 SFKXESEFELNLSVGDIVIVRKISSNGWAEGECKGKAGWFPHAYV 273 ++ E E EL+L G VIV + S+GW G G+ GWFP YV Sbjct: 116 NYMAEREDELSLIKGTKVIVMEKCSDGWWRGSYNGQVGWFPSNYV 160
>CRK_XENLA (P87378) SH2/SH3 adaptor crk (Adapter molecule crk) (CRK2)| Length = 296 Score = 41.6 bits (96), Expect = 8e-04 Identities = 21/41 (51%), Positives = 26/41 (63%) Frame = -1 Query: 380 LNLSVGDIVIVRKISSNGWAEGECKGKAGWFPHAYVERRER 258 L L VGD+V V KI+ +G EGEC GK G FP +V E+ Sbjct: 249 LALEVGDLVKVTKINVSGQWEGECNGKYGHFPFTHVRLLEQ 289
>BZZ1_YEAST (P38822) Protein BZZ1| Length = 633 Score = 41.6 bits (96), Expect = 8e-04 Identities = 17/49 (34%), Positives = 31/49 (63%), Gaps = 1/49 (2%) Frame = -1 Query: 419 EALDSFKXESEFELNLSVGDIV-IVRKISSNGWAEGECKGKAGWFPHAY 276 EA+ +++ + + E+++ GDI+ ++R +GW GEC G G FP +Y Sbjct: 583 EAIYAYEAQGDDEISIDPGDIITVIRGDDGSGWTYGECDGLKGLFPTSY 631
>YB65_SCHPO (Q09746) Hypothetical protein C12C2.05c in chromosome II| Length = 642 Score = 41.6 bits (96), Expect = 8e-04 Identities = 19/50 (38%), Positives = 31/50 (62%), Gaps = 1/50 (2%) Frame = -1 Query: 419 EALDSFKXESEFELNLSVGDIV-IVRKISSNGWAEGECKGKAGWFPHAYV 273 +AL ++ +S+ EL++ GDI+ + + + NGW+EG G G FP YV Sbjct: 590 KALYAYTAQSDMELSIQEGDIIQVTNRNAGNGWSEGILNGVTGQFPANYV 639
>DNMBP_MOUSE (Q6TXD4) Dynamin-binding protein (Scaffold protein Tuba)| Length = 1580 Score = 41.6 bits (96), Expect = 8e-04 Identities = 21/51 (41%), Positives = 28/51 (54%) Frame = -1 Query: 422 GEALDSFKXESEFELNLSVGDIVIVRKISSNGWAEGECKGKAGWFPHAYVE 270 G AL F+ EL+ VGD + + +GW EG KGK G FPH +V+ Sbjct: 249 GIALYRFQALETNELDFEVGDRIQILGTLEDGWLEGCLKGKTGVFPHRFVK 299 Score = 39.7 bits (91), Expect = 0.003 Identities = 17/49 (34%), Positives = 27/49 (55%) Frame = -1 Query: 416 ALDSFKXESEFELNLSVGDIVIVRKISSNGWAEGECKGKAGWFPHAYVE 270 AL + + EL+ GD++ + + GW EGE +G+ G FP +VE Sbjct: 153 ALMGLSAQLDEELDFREGDLITIIGVPEPGWFEGELEGRRGIFPEGFVE 201 Score = 29.6 bits (65), Expect = 3.3 Identities = 14/38 (36%), Positives = 21/38 (55%) Frame = -1 Query: 383 ELNLSVGDIVIVRKISSNGWAEGECKGKAGWFPHAYVE 270 EL L VGD++ V + W G+ + G FP ++VE Sbjct: 20 ELPLFVGDVIEVLAVVDEFWLLGKKEDVTGQFPSSFVE 57
>NCF4_HUMAN (Q15080) Neutrophil cytosol factor 4 (NCF-4) (Neutrophil NADPH| oxidase factor 4) (p40-phox) (p40phox) Length = 339 Score = 40.8 bits (94), Expect = 0.001 Identities = 18/50 (36%), Positives = 27/50 (54%) Frame = -1 Query: 419 EALDSFKXESEFELNLSVGDIVIVRKISSNGWAEGECKGKAGWFPHAYVE 270 EAL F S+ ELN GD++ + + W EG +G G FP ++V+ Sbjct: 176 EALFDFTGNSKLELNFKAGDVIFLLSRINKDWLEGTVRGATGIFPLSFVK 225
>SH3G2_RAT (O35179) SH3-containing GRB2-like protein 2 (EC 2.3.1.-) (SH3| domain protein 2A) (Endophilin 1) (SH3p4) (Fragment) Length = 248 Score = 40.4 bits (93), Expect = 0.002 Identities = 20/49 (40%), Positives = 27/49 (55%) Frame = -1 Query: 416 ALDSFKXESEFELNLSVGDIVIVRKISSNGWAEGECKGKAGWFPHAYVE 270 AL F+ E+E EL GDI+ + W EG G++G+FP YVE Sbjct: 193 ALYDFEPENEGELGFKEGDIITLTNQIDENWYEGMLHGQSGFFPINYVE 241
>SRBS1_MOUSE (Q62417) Sorbin and SH3 domain-containing protein 1 (Ponsin)| (c-Cbl-associated protein) (CAP) (SH3 domain protein 5) (SH3P12) Length = 1290 Score = 40.4 bits (93), Expect = 0.002 Identities = 18/45 (40%), Positives = 25/45 (55%) Frame = -1 Query: 404 FKXESEFELNLSVGDIVIVRKISSNGWAEGECKGKAGWFPHAYVE 270 FK ++ EL L GD+V + + W EGE G+ G FP Y+E Sbjct: 1060 FKAQTLKELPLQKGDVVYIYRQIDQNWYEGEHHGRVGIFPRTYIE 1104 Score = 31.6 bits (70), Expect = 0.87 Identities = 21/57 (36%), Positives = 31/57 (54%), Gaps = 2/57 (3%) Frame = -1 Query: 434 DLFLGEALDSFKXESEFELNLSVGDIVIVRKISSNGWAEGECK--GKAGWFPHAYVE 270 DL +AL S+ +++ EL L GDIV V + +GW G + + G FP YV+ Sbjct: 1230 DLCSYQALYSYVPQNDDELELRDGDIVDVMEKCDDGWFVGTSRRTRQFGTFPGNYVK 1286
>DNMBP_HUMAN (Q6XZF7) Dynamin-binding protein (Scaffold protein Tuba)| Length = 1577 Score = 40.4 bits (93), Expect = 0.002 Identities = 19/51 (37%), Positives = 28/51 (54%) Frame = -1 Query: 422 GEALDSFKXESEFELNLSVGDIVIVRKISSNGWAEGECKGKAGWFPHAYVE 270 G AL F+ EL+ VGD + + +GW EG KG+ G FP+ +V+ Sbjct: 248 GVALYRFQALEPNELDFEVGDKIRILATLEDGWLEGSLKGRTGIFPYRFVK 298 Score = 40.0 bits (92), Expect = 0.002 Identities = 17/49 (34%), Positives = 27/49 (55%) Frame = -1 Query: 416 ALDSFKXESEFELNLSVGDIVIVRKISSNGWAEGECKGKAGWFPHAYVE 270 AL + + EL+ GD++ + + GW EGE +G+ G FP +VE Sbjct: 152 ALMGLSAQLDEELDFREGDVITIIGVPEPGWFEGELEGRRGIFPEGFVE 200 Score = 32.3 bits (72), Expect = 0.51 Identities = 21/55 (38%), Positives = 30/55 (54%), Gaps = 1/55 (1%) Frame = -1 Query: 404 FKXESEFELNLSVGDIVIVRKISSNGWAEG-ECKGKAGWFPHAYVERRERVLASK 243 F + L L GD+VI+ I + GW +G C G G+FP + V RE L+S+ Sbjct: 77 FTSQELDNLPLHRGDLVILDGIPTAGWLQGRSCWGARGFFPSSCV--RELCLSSQ 129 Score = 30.0 bits (66), Expect = 2.5 Identities = 15/38 (39%), Positives = 21/38 (55%) Frame = -1 Query: 383 ELNLSVGDIVIVRKISSNGWAEGECKGKAGWFPHAYVE 270 EL L VGDI+ V + W G+ + G FP ++VE Sbjct: 20 ELPLFVGDIIEVLAVVDEFWLLGKKEDVTGQFPSSFVE 57
>VAV2_HUMAN (P52735) Protein vav-2| Length = 878 Score = 40.4 bits (93), Expect = 0.002 Identities = 20/48 (41%), Positives = 26/48 (54%), Gaps = 2/48 (4%) Frame = -1 Query: 407 SFKXESEFELNLSVGDIVIV--RKISSNGWAEGECKGKAGWFPHAYVE 270 +F EL+L GD+V + R GW +GE G+ GWFP YVE Sbjct: 826 NFAARDMRELSLREGDVVRIYSRIGGDQGWWKGETNGRIGWFPSTYVE 873
>VAV2_MOUSE (Q60992) Protein vav-2| Length = 868 Score = 40.4 bits (93), Expect = 0.002 Identities = 20/48 (41%), Positives = 26/48 (54%), Gaps = 2/48 (4%) Frame = -1 Query: 407 SFKXESEFELNLSVGDIVIV--RKISSNGWAEGECKGKAGWFPHAYVE 270 +F EL+L GD+V + R GW +GE G+ GWFP YVE Sbjct: 816 NFAARDMRELSLREGDVVKIYSRIGGDQGWWKGETNGRIGWFPSTYVE 863
>MYSC_ACACA (P10569) Myosin IC heavy chain| Length = 1168 Score = 40.0 bits (92), Expect = 0.002 Identities = 23/56 (41%), Positives = 29/56 (51%) Frame = -1 Query: 416 ALDSFKXESEFELNLSVGDIVIVRKISSNGWAEGECKGKAGWFPHAYVERRERVLA 249 AL F E+ EL + G +V V S+ W EGE G+ G FP +YVE R A Sbjct: 983 ALYDFAAENPDELTFNEGAVVTVINKSNPDWWEGELNGQRGVFPASYVELIPRAAA 1038
>SH3G3_MOUSE (Q62421) SH3-containing GRB2-like protein 3 (SH3 domain protein 2C)| (SH3p13) Length = 347 Score = 40.0 bits (92), Expect = 0.002 Identities = 19/48 (39%), Positives = 27/48 (56%) Frame = -1 Query: 413 LDSFKXESEFELNLSVGDIVIVRKISSNGWAEGECKGKAGWFPHAYVE 270 L F+ E+E EL GDI+ + W EG +G++G+FP YVE Sbjct: 293 LYDFEPENEGELGFKEGDIITLTNQIDENWYEGMLRGESGFFPINYVE 340
>CRK_CHICK (Q04929) Proto-oncogene C-crk (P38)| Length = 305 Score = 40.0 bits (92), Expect = 0.002 Identities = 19/36 (52%), Positives = 24/36 (66%) Frame = -1 Query: 380 LNLSVGDIVIVRKISSNGWAEGECKGKAGWFPHAYV 273 L L VG++V V KI+ +G EGEC GK G FP +V Sbjct: 257 LALEVGELVKVTKINMSGQWEGECNGKRGHFPFTHV 292
>OSTF1_MOUSE (Q62422) Osteoclast-stimulating factor 1 (SH3 domain protein 3)| Length = 215 Score = 40.0 bits (92), Expect = 0.002 Identities = 18/48 (37%), Positives = 26/48 (54%) Frame = -1 Query: 416 ALDSFKXESEFELNLSVGDIVIVRKISSNGWAEGECKGKAGWFPHAYV 273 AL +F+ + EL GDI+ + +S W +G CKG+ G P YV Sbjct: 19 ALYTFEPRTPDELYFEEGDIIYITDMSDTSWWKGTCKGRTGLIPSNYV 66
>NCK2_HUMAN (O43639) Cytoplasmic protein NCK2 (NCK adaptor protein 2) (SH2/SH3| adaptor protein NCK-beta) (Nck-2) Length = 380 Score = 40.0 bits (92), Expect = 0.002 Identities = 21/57 (36%), Positives = 29/57 (50%) Frame = -1 Query: 407 SFKXESEFELNLSVGDIVIVRKISSNGWAEGECKGKAGWFPHAYVERRERVLASKVP 237 ++ E E EL+L G V V + S+GW G G+ GWFP YV A++ P Sbjct: 121 AYVAEREDELSLVKGSRVTVMEKCSDGWWRGSYNGQIGWFPSNYVLEEVDEAAAESP 177
>SH3G3_RAT (O35180) SH3-containing GRB2-like protein 3 (SH3 domain protein 2C)| (SH3p13) (Fragment) Length = 291 Score = 40.0 bits (92), Expect = 0.002 Identities = 19/48 (39%), Positives = 27/48 (56%) Frame = -1 Query: 413 LDSFKXESEFELNLSVGDIVIVRKISSNGWAEGECKGKAGWFPHAYVE 270 L F+ E+E EL GDI+ + W EG +G++G+FP YVE Sbjct: 237 LYDFEPENEGELGFKEGDIITLTNQIDENWYEGMLRGESGFFPINYVE 284
>SH3G1_HUMAN (Q99961) SH3-containing GRB2-like protein 1 (SH3 domain protein 2B)| (Extra eleven-nineteen leukemia fusion gene) (EEN) (EEN fusion partner of MLL) Length = 368 Score = 40.0 bits (92), Expect = 0.002 Identities = 18/50 (36%), Positives = 29/50 (58%) Frame = -1 Query: 419 EALDSFKXESEFELNLSVGDIVIVRKISSNGWAEGECKGKAGWFPHAYVE 270 +AL F+ E++ EL GD++ + W EG G++G+FP +YVE Sbjct: 312 KALYDFEPENDGELGFHEGDVITLTNQIDENWYEGMLDGQSGFFPLSYVE 361
>ARHG5_HUMAN (Q12774) Rho guanine nucleotide exchange factor 5 (Guanine| nucleotide regulatory protein TIM) (Oncogene TIM) (p60 TIM) (Transforming immortalized mammary oncogene) Length = 519 Score = 39.7 bits (91), Expect = 0.003 Identities = 21/52 (40%), Positives = 29/52 (55%), Gaps = 2/52 (3%) Frame = -1 Query: 419 EALDSFKXESEFELNLSVGDIVIVRKISSNGWAEGE--CKGKAGWFPHAYVE 270 + L ++K EL L D+V+V + SS+GW EG G+ GWFP VE Sbjct: 438 QCLRAYKPRENDELALEKADVVMVTQQSSDGWLEGVRLSDGERGWFPVQQVE 489
>ITSN2_HUMAN (Q9NZM3) Intersectin-2 (SH3 domain-containing protein 1B) (SH3P18)| (SH3P18-like WASP-associated protein) Length = 1696 Score = 39.7 bits (91), Expect = 0.003 Identities = 19/52 (36%), Positives = 29/52 (55%), Gaps = 2/52 (3%) Frame = -1 Query: 416 ALDSFKXESEFELNLSVGDIVIV--RKISSNGWAEGECKGKAGWFPHAYVER 267 AL F+ + E++ + GDI+ V + + GW G +G GWFP YVE+ Sbjct: 763 ALYPFEARNHDEMSFNSGDIIQVDEKTVGEPGWLYGSFQGNFGWFPCNYVEK 814 Score = 38.5 bits (88), Expect = 0.007 Identities = 20/50 (40%), Positives = 28/50 (56%) Frame = -1 Query: 419 EALDSFKXESEFELNLSVGDIVIVRKISSNGWAEGECKGKAGWFPHAYVE 270 +AL S+ + + LN S DI+ V + N W GE G GWFP +YV+ Sbjct: 903 QALCSWTAKKDNHLNFSKHDIITVLEQQENWWF-GEVHGGRGWFPKSYVK 951 Score = 35.4 bits (80), Expect = 0.061 Identities = 14/57 (24%), Positives = 33/57 (57%), Gaps = 5/57 (8%) Frame = -1 Query: 425 LGEALDSFKXESEFELNLSVGDIVIVRKISSNGWAEGEC-----KGKAGWFPHAYVE 270 + + ++ +L+L+ G ++++ K +++GW +GE K + GWFP ++V+ Sbjct: 1056 IAQVTSAYVASGSEQLSLAPGQLILILKKNTSGWWQGELQARGKKRQKGWFPASHVK 1112 Score = 33.5 bits (75), Expect = 0.23 Identities = 16/49 (32%), Positives = 24/49 (48%) Frame = -1 Query: 416 ALDSFKXESEFELNLSVGDIVIVRKISSNGWAEGECKGKAGWFPHAYVE 270 A+ + +E EL+ S G ++ V W +GE G G FP YV+ Sbjct: 1133 AMYDYAANNEDELSFSKGQLINVMNKDDPDWWQGEINGVTGLFPSNYVK 1181
>SRC8_HUMAN (Q14247) Src substrate cortactin (Amplaxin) (Oncogene EMS1)| Length = 550 Score = 39.7 bits (91), Expect = 0.003 Identities = 18/52 (34%), Positives = 29/52 (55%) Frame = -1 Query: 416 ALDSFKXESEFELNLSVGDIVIVRKISSNGWAEGECKGKAGWFPHAYVERRE 261 AL ++ + E++ DI+ ++ +GW G CKG+ G FP YVE R+ Sbjct: 499 ALYDYQAAGDDEISFDPDDIITNIEMIDDGWWRGVCKGRYGLFPANYVELRQ 550
>SRC8_CHICK (Q01406) Src substrate protein p85 (p80) (Cortactin)| Length = 563 Score = 39.7 bits (91), Expect = 0.003 Identities = 18/52 (34%), Positives = 29/52 (55%) Frame = -1 Query: 416 ALDSFKXESEFELNLSVGDIVIVRKISSNGWAEGECKGKAGWFPHAYVERRE 261 AL ++ + E++ DI+ ++ +GW G CKG+ G FP YVE R+ Sbjct: 512 ALYDYQAAGDDEISFDPDDIITNIEMIDDGWWRGVCKGRYGLFPANYVELRQ 563
>CRK_DROME (Q9XYM0) Adapter molecule Crk| Length = 271 Score = 39.7 bits (91), Expect = 0.003 Identities = 19/37 (51%), Positives = 23/37 (62%) Frame = -1 Query: 380 LNLSVGDIVIVRKISSNGWAEGECKGKAGWFPHAYVE 270 L L +GDI+ V K + NG EGE GK G FP +VE Sbjct: 220 LKLEIGDIIKVTKTNINGQWEGELNGKNGHFPFTHVE 256
>SRC8_MOUSE (Q60598) Src substrate cortactin| Length = 546 Score = 39.7 bits (91), Expect = 0.003 Identities = 18/52 (34%), Positives = 29/52 (55%) Frame = -1 Query: 416 ALDSFKXESEFELNLSVGDIVIVRKISSNGWAEGECKGKAGWFPHAYVERRE 261 AL ++ + E++ DI+ ++ +GW G CKG+ G FP YVE R+ Sbjct: 495 ALYDYQAAGDDEISFDPDDIITNIEMIDDGWWRGVCKGRYGLFPANYVELRQ 546
>CD2AP_MOUSE (Q9JLQ0) CD2-associated protein (Mesenchym-to-epithelium transition| protein with SH3 domains 1) (METS-1) Length = 637 Score = 39.7 bits (91), Expect = 0.003 Identities = 18/43 (41%), Positives = 27/43 (62%), Gaps = 1/43 (2%) Frame = -1 Query: 383 ELNLSVGDIVI-VRKISSNGWAEGECKGKAGWFPHAYVERRER 258 EL + VG+I+ V+K+ GW EGE G+ G FP +V+ +R Sbjct: 17 ELTIRVGEIIRNVKKLQEEGWLEGELNGRRGMFPDNFVKEIKR 59 Score = 36.2 bits (82), Expect = 0.035 Identities = 18/53 (33%), Positives = 27/53 (50%) Frame = -1 Query: 419 EALDSFKXESEFELNLSVGDIVIVRKISSNGWAEGECKGKAGWFPHAYVERRE 261 + L + ++E EL L VGD++ V + GW G K G FP +V+ E Sbjct: 114 KVLFDYSPQNEDELELIVGDVIDVIEEVEEGWWSGTLNNKLGLFPSNFVKELE 166 Score = 29.3 bits (64), Expect = 4.3 Identities = 15/38 (39%), Positives = 21/38 (55%), Gaps = 2/38 (5%) Frame = -1 Query: 392 SEFELNLSVGDIV--IVRKISSNGWAEGECKGKAGWFP 285 +E EL G+I+ I ++ GW +GE GK G FP Sbjct: 284 NEDELTFREGEIIHLISKETGEAGWWKGELNGKEGVFP 321
>MYOD_DICDI (P34109) Myosin ID heavy chain| Length = 1109 Score = 39.7 bits (91), Expect = 0.003 Identities = 20/50 (40%), Positives = 27/50 (54%) Frame = -1 Query: 419 EALDSFKXESEFELNLSVGDIVIVRKISSNGWAEGECKGKAGWFPHAYVE 270 +AL F ES EL+ GDI+ V SS W + E KG+ G P Y++ Sbjct: 964 KALYDFDAESSMELSFKEGDILTVLDQSSGDWWDAELKGRRGKVPSNYLQ 1013
>SH3G2_HUMAN (Q99962) SH3-containing GRB2-like protein 2 (EC 2.3.1.-) (SH3| domain protein 2A) (Endophilin 1) (EEN-B1) Length = 352 Score = 39.7 bits (91), Expect = 0.003 Identities = 20/49 (40%), Positives = 26/49 (53%) Frame = -1 Query: 416 ALDSFKXESEFELNLSVGDIVIVRKISSNGWAEGECKGKAGWFPHAYVE 270 AL F+ E+E EL GDI+ + W EG G +G+FP YVE Sbjct: 297 ALYDFEPENEGELGFKEGDIITLTNQIDENWYEGMLHGHSGFFPINYVE 345
>CRK_RAT (Q63768) Proto-oncogene C-crk (P38) (Adapter molecule crk)| Length = 304 Score = 39.7 bits (91), Expect = 0.003 Identities = 19/36 (52%), Positives = 24/36 (66%) Frame = -1 Query: 380 LNLSVGDIVIVRKISSNGWAEGECKGKAGWFPHAYV 273 L L VG++V V KI+ +G EGEC GK G FP +V Sbjct: 256 LALEVGELVKVTKINVSGQWEGECNGKRGHFPFTHV 291 Score = 31.6 bits (70), Expect = 0.87 Identities = 20/58 (34%), Positives = 26/58 (44%), Gaps = 1/58 (1%) Frame = -1 Query: 416 ALDSFKXESEFELNLSVGDIVIVR-KISSNGWAEGECKGKAGWFPHAYVERRERVLAS 246 AL F E +L GDI+ +R K W + +GK G P YVE+ AS Sbjct: 139 ALFDFNGNDEEDLPFKKGDILRIRDKPEEQWWNAEDSEGKRGMIPVPYVEKYRPASAS 196
>CRK_MOUSE (Q64010) Proto-oncogene C-crk (P38) (Adapter molecule crk)| Length = 304 Score = 39.7 bits (91), Expect = 0.003 Identities = 19/36 (52%), Positives = 24/36 (66%) Frame = -1 Query: 380 LNLSVGDIVIVRKISSNGWAEGECKGKAGWFPHAYV 273 L L VG++V V KI+ +G EGEC GK G FP +V Sbjct: 256 LALEVGELVKVTKINVSGQWEGECNGKRGHFPFTHV 291 Score = 31.6 bits (70), Expect = 0.87 Identities = 20/58 (34%), Positives = 26/58 (44%), Gaps = 1/58 (1%) Frame = -1 Query: 416 ALDSFKXESEFELNLSVGDIVIVR-KISSNGWAEGECKGKAGWFPHAYVERRERVLAS 246 AL F E +L GDI+ +R K W + +GK G P YVE+ AS Sbjct: 139 ALFDFNGNDEEDLPFKKGDILRIRDKPEEQWWNAEDSEGKRGMIPVPYVEKYRPASAS 196
>CD2AP_HUMAN (Q9Y5K6) CD2-associated protein (Cas ligand with multiple SH3| domains) (Adapter protein CMS) Length = 639 Score = 39.7 bits (91), Expect = 0.003 Identities = 18/43 (41%), Positives = 27/43 (62%), Gaps = 1/43 (2%) Frame = -1 Query: 383 ELNLSVGDIVI-VRKISSNGWAEGECKGKAGWFPHAYVERRER 258 EL + VG+I+ V+K+ GW EGE G+ G FP +V+ +R Sbjct: 17 ELTIRVGEIIRNVKKLQEEGWLEGELNGRRGMFPDNFVKEIKR 59 Score = 37.0 bits (84), Expect = 0.021 Identities = 17/45 (37%), Positives = 24/45 (53%) Frame = -1 Query: 395 ESEFELNLSVGDIVIVRKISSNGWAEGECKGKAGWFPHAYVERRE 261 ++E EL L VGDI+ + + GW G K G FP +V+ E Sbjct: 122 QNEDELELKVGDIIDINEEVEEGWWSGTLNNKLGLFPSNFVKELE 166 Score = 30.8 bits (68), Expect = 1.5 Identities = 16/45 (35%), Positives = 24/45 (53%), Gaps = 2/45 (4%) Frame = -1 Query: 413 LDSFKXESEFELNLSVGDIV--IVRKISSNGWAEGECKGKAGWFP 285 L +++ +E EL G+I+ I ++ GW GE GK G FP Sbjct: 277 LFAYEGTNEDELTFKEGEIIHLISKETGEAGWWRGELNGKEGVFP 321
>MYOB_DICDI (P34092) Myosin IB heavy chain| Length = 1111 Score = 39.3 bits (90), Expect = 0.004 Identities = 18/51 (35%), Positives = 29/51 (56%), Gaps = 1/51 (1%) Frame = -1 Query: 419 EALDSFKXESEFELNLSVGDIVIVRKISSNGWAEGECK-GKAGWFPHAYVE 270 +AL + S EL+ GDI+ + + + GW +GE K G+ GW P Y++ Sbjct: 1059 KALYDYDASSTDELSFKEGDIIFIVQKDNGGWTQGELKSGQKGWAPTNYLQ 1109
>NCF1_HUMAN (P14598) Neutrophil cytosol factor 1 (NCF-1) (Neutrophil NADPH| oxidase factor 1) (47 kDa neutrophil oxidase factor) (p47-phox) (NCF-47K) (47 kDa autosomal chronic granulomatous disease protein) (NOXO2) Length = 390 Score = 38.9 bits (89), Expect = 0.005 Identities = 18/49 (36%), Positives = 29/49 (59%) Frame = -1 Query: 416 ALDSFKXESEFELNLSVGDIVIVRKISSNGWAEGECKGKAGWFPHAYVE 270 A+ ++ S E+ LS GD+V V + S +GW + K K GW P +++E Sbjct: 163 AIADYEKTSGSEMALSTGDVVEVVEKSESGWWFCQMKAKRGWIPASFLE 211
>NCF4_MOUSE (P97369) Neutrophil cytosol factor 4 (NCF-4) (Neutrophil NADPH| oxidase factor 4) (p40-phox) (p40phox) Length = 339 Score = 38.9 bits (89), Expect = 0.005 Identities = 17/50 (34%), Positives = 27/50 (54%) Frame = -1 Query: 419 EALDSFKXESEFELNLSVGDIVIVRKISSNGWAEGECKGKAGWFPHAYVE 270 EAL F S+ EL+ GD++ + + W EG +G G FP ++V+ Sbjct: 176 EALFDFTGNSKLELSFKAGDVIFLLSKINKDWLEGTSQGATGIFPGSFVK 225
>SH3K1_MOUSE (Q8R550) SH3-domain kinase-binding protein 1 (SH3-containing,| expressed in tumorigenic astrocytes) (Regulator of ubiquitous kinase) (Ruk) Length = 709 Score = 38.5 bits (88), Expect = 0.007 Identities = 17/61 (27%), Positives = 35/61 (57%), Gaps = 5/61 (8%) Frame = -1 Query: 404 FKXESEFELNLSVGDIVIVRKISSNGWAEGECKGKAGWFPHAYV-----ERRERVLASKV 240 ++ + + EL +SVG+++ + GW EG+ G+ G FP +V + ++ +L++K Sbjct: 10 YQAQHDDELTISVGEVITNIRKEDGGWWEGQINGRRGLFPDNFVREIKKDMKKDLLSNKA 69 Query: 239 P 237 P Sbjct: 70 P 70 Score = 38.1 bits (87), Expect = 0.009 Identities = 18/46 (39%), Positives = 26/46 (56%) Frame = -1 Query: 407 SFKXESEFELNLSVGDIVIVRKISSNGWAEGECKGKAGWFPHAYVE 270 S+ +++ EL L VGDI+ V GW EG GK G FP +++ Sbjct: 108 SYLPQNDDELELKVGDIIEVVGEVEEGWWEGVLNGKTGMFPSNFIK 153 Score = 33.5 bits (75), Expect = 0.23 Identities = 17/47 (36%), Positives = 27/47 (57%), Gaps = 2/47 (4%) Frame = -1 Query: 404 FKXESEFELNLSVGDIV--IVRKISSNGWAEGECKGKAGWFPHAYVE 270 ++ +++ EL + GDIV I + GW EGE G+ G FP +V+ Sbjct: 322 YEAQNDDELTIKEGDIVTLINKDCIDVGWWEGELNGRRGVFPDNFVK 368
>MYO1E_HUMAN (Q12965) Myosin Ie (Myosin Ic)| Length = 1109 Score = 38.5 bits (88), Expect = 0.007 Identities = 17/51 (33%), Positives = 29/51 (56%) Frame = -1 Query: 419 EALDSFKXESEFELNLSVGDIVIVRKISSNGWAEGECKGKAGWFPHAYVER 267 +AL ++ + EL+ + DI+ + K +GW G +GK G FP+ YV + Sbjct: 1058 KALYAYDAQDTDELSFNANDIIDIIKEDPSGWWTGRLRGKPGLFPNNYVTK 1108
>SH3K1_HUMAN (Q96B97) SH3-domain kinase-binding protein 1 (Cbl-interacting| protein of 85 kDa) (Human Src-family kinase-binding protein 1) (HSB-1) (CD2-binding protein 3) (CD2BP3) Length = 665 Score = 38.5 bits (88), Expect = 0.007 Identities = 19/61 (31%), Positives = 33/61 (54%), Gaps = 5/61 (8%) Frame = -1 Query: 404 FKXESEFELNLSVGDIVIVRKISSNGWAEGECKGKAGWFPHAYV-----ERRERVLASKV 240 ++ + + EL +SVG+I+ + GW EG+ G+ G FP +V E ++ L +K Sbjct: 10 YQAQHDDELTISVGEIITNIRKEDGGWWEGQINGRRGLFPDNFVREIKKEMKKDPLTNKA 69 Query: 239 P 237 P Sbjct: 70 P 70 Score = 38.1 bits (87), Expect = 0.009 Identities = 18/46 (39%), Positives = 26/46 (56%) Frame = -1 Query: 407 SFKXESEFELNLSVGDIVIVRKISSNGWAEGECKGKAGWFPHAYVE 270 S+ +++ EL L VGDI+ V GW EG GK G FP +++ Sbjct: 108 SYLPQNDDELELKVGDIIEVVGEVEEGWWEGVLNGKTGMFPSNFIK 153 Score = 33.5 bits (75), Expect = 0.23 Identities = 17/47 (36%), Positives = 27/47 (57%), Gaps = 2/47 (4%) Frame = -1 Query: 404 FKXESEFELNLSVGDIV--IVRKISSNGWAEGECKGKAGWFPHAYVE 270 ++ +++ EL + GDIV I + GW EGE G+ G FP +V+ Sbjct: 278 YEAQNDDELTIKEGDIVTLINKDCIDVGWWEGELNGRRGVFPDNFVK 324
>SH3G1_RAT (O35964) SH3-containing GRB2-like protein 1 (SH3 domain protein 2B)| (SH3p8) Length = 368 Score = 38.5 bits (88), Expect = 0.007 Identities = 17/50 (34%), Positives = 29/50 (58%) Frame = -1 Query: 419 EALDSFKXESEFELNLSVGDIVIVRKISSNGWAEGECKGKAGWFPHAYVE 270 +AL F+ E++ EL GD++ + W EG G++G+FP +YV+ Sbjct: 312 KALYDFEPENDGELGFREGDLITLTNQIDENWYEGMLHGQSGFFPLSYVQ 361
>SH3G1_MOUSE (Q62419) SH3-containing GRB2-like protein 1 (SH3 domain protein 2B)| (SH3p8) Length = 368 Score = 38.5 bits (88), Expect = 0.007 Identities = 17/50 (34%), Positives = 29/50 (58%) Frame = -1 Query: 419 EALDSFKXESEFELNLSVGDIVIVRKISSNGWAEGECKGKAGWFPHAYVE 270 +AL F+ E++ EL GD++ + W EG G++G+FP +YV+ Sbjct: 312 KALYDFEPENDGELGFREGDLITLTNQIDENWYEGMLHGQSGFFPLSYVQ 361
>NCF1_MOUSE (Q09014) Neutrophil cytosol factor 1 (NCF-1) (Neutrophil NADPH| oxidase factor 1) (47 kDa neutrophil oxidase factor) (p47-phox) (NCF-47K) Length = 390 Score = 38.1 bits (87), Expect = 0.009 Identities = 17/49 (34%), Positives = 29/49 (59%) Frame = -1 Query: 416 ALDSFKXESEFELNLSVGDIVIVRKISSNGWAEGECKGKAGWFPHAYVE 270 A+ ++ S E+ ++ GD+V V + S +GW + K K GW P +Y+E Sbjct: 163 AIADYEKSSGTEMTVATGDVVDVVEKSESGWWFCQMKTKRGWVPASYLE 211
>ABI2_HUMAN (Q9NYB9) Abl interactor 2 (Abelson interactor 2) (Abi-2)| (Abl-binding protein 3) (AblBP3) (Arg-binding protein 1) (ArgBP1) Length = 513 Score = 38.1 bits (87), Expect = 0.009 Identities = 19/49 (38%), Positives = 26/49 (53%) Frame = -1 Query: 416 ALDSFKXESEFELNLSVGDIVIVRKISSNGWAEGECKGKAGWFPHAYVE 270 A+ + + E EL+ G I+ V K + +GW EG G G FP YVE Sbjct: 458 AIYDYTKDKEDELSFQEGAIIYVIKKNDDGWYEGVMNGVTGLFPGNYVE 506
>SH3K1_RAT (Q925Q9) SH3-domain kinase-binding protein 1 (SH3-containing,| expressed in tumorigenic astrocytes) (Regulator of ubiquitous kinase) (Ruk) Length = 709 Score = 38.1 bits (87), Expect = 0.009 Identities = 18/46 (39%), Positives = 26/46 (56%) Frame = -1 Query: 407 SFKXESEFELNLSVGDIVIVRKISSNGWAEGECKGKAGWFPHAYVE 270 S+ +++ EL L VGDI+ V GW EG GK G FP +++ Sbjct: 108 SYLPQNDDELELKVGDIIEVVGEVEEGWWEGVLNGKTGMFPSNFIK 153 Score = 38.1 bits (87), Expect = 0.009 Identities = 17/61 (27%), Positives = 34/61 (55%), Gaps = 5/61 (8%) Frame = -1 Query: 404 FKXESEFELNLSVGDIVIVRKISSNGWAEGECKGKAGWFPHAYVER-----RERVLASKV 240 ++ + + EL +SVG+++ + GW EG+ G+ G FP +V ++ +L++K Sbjct: 10 YQAQHDDELTISVGEVITNIRKEDGGWWEGQINGRRGLFPDNFVREIKKDVKKDLLSNKA 69 Query: 239 P 237 P Sbjct: 70 P 70 Score = 33.5 bits (75), Expect = 0.23 Identities = 17/47 (36%), Positives = 27/47 (57%), Gaps = 2/47 (4%) Frame = -1 Query: 404 FKXESEFELNLSVGDIV--IVRKISSNGWAEGECKGKAGWFPHAYVE 270 ++ +++ EL + GDIV I + GW EGE G+ G FP +V+ Sbjct: 322 YEAQNDDELTIKEGDIVTLINKDCIDVGWWEGELNGRRGVFPDNFVK 368
>ABI2_MOUSE (P62484) Abl interactor 2 (Abelson interactor 2) (Abi-2)| Length = 446 Score = 38.1 bits (87), Expect = 0.009 Identities = 19/49 (38%), Positives = 26/49 (53%) Frame = -1 Query: 416 ALDSFKXESEFELNLSVGDIVIVRKISSNGWAEGECKGKAGWFPHAYVE 270 A+ + + E EL+ G I+ V K + +GW EG G G FP YVE Sbjct: 391 AIYDYTKDKEDELSFQEGAIIYVIKKNDDGWYEGVMNGVTGLFPGNYVE 439
>GRB2_CHICK (Q07883) Growth factor receptor-bound protein 2 (Adapter protein| GRB2) (SH2/SH3 adapter GRB2) Length = 217 Score = 38.1 bits (87), Expect = 0.009 Identities = 19/49 (38%), Positives = 24/49 (48%) Frame = -1 Query: 419 EALDSFKXESEFELNLSVGDIVIVRKISSNGWAEGECKGKAGWFPHAYV 273 +AL F + E EL GD + V S W +G C G+ G FP YV Sbjct: 162 QALFDFDPQEEGELGFRRGDFIQVLDNSDPNWWKGACHGQTGMFPRNYV 210
>MYO1E_RAT (Q63356) Myosin Ie (Myosin heavy chain myr 3)| Length = 1107 Score = 38.1 bits (87), Expect = 0.009 Identities = 16/51 (31%), Positives = 29/51 (56%) Frame = -1 Query: 419 EALDSFKXESEFELNLSVGDIVIVRKISSNGWAEGECKGKAGWFPHAYVER 267 +AL ++ + EL+ + D++ + K +GW G +GK G FP+ YV + Sbjct: 1056 KALYAYDAQDTDELSFNANDVIDIIKEDPSGWWTGRLRGKQGLFPNNYVTK 1106
>ABI1_RAT (Q9QZM5) Abl interactor 1 (Abelson interactor 1) (Abi-1) (Eps8 SH3| domain-binding protein) (Eps8-binding protein) (e3B1) Length = 475 Score = 37.7 bits (86), Expect = 0.012 Identities = 18/49 (36%), Positives = 26/49 (53%) Frame = -1 Query: 416 ALDSFKXESEFELNLSVGDIVIVRKISSNGWAEGECKGKAGWFPHAYVE 270 A+ + + + EL+ G I+ V K + +GW EG C G FP YVE Sbjct: 420 AIYDYTKDKDDELSFKEGAIIYVIKKNDDGWFEGVCNRVTGLFPGNYVE 468
>SH3G3_HUMAN (Q99963) SH3-containing GRB2-like protein 3 (SH3 domain protein 2C)| (EEN-B2) Length = 347 Score = 37.7 bits (86), Expect = 0.012 Identities = 18/48 (37%), Positives = 26/48 (54%) Frame = -1 Query: 413 LDSFKXESEFELNLSVGDIVIVRKISSNGWAEGECKGKAGWFPHAYVE 270 L F+ E++ EL GDI+ + W EG G++G+FP YVE Sbjct: 293 LYDFEPENQGELGFKEGDIITLTNQIDENWYEGMIHGESGFFPINYVE 340
>ABI1_MOUSE (Q8CBW3) Abl interactor 1 (Abelson interactor 1) (Abi-1) (Spectrin| SH3 domain-binding protein 1) (Eps8 SH3 domain-binding protein) (Eps8-binding protein) (e3B1) (Ablphilin-1) Length = 480 Score = 37.7 bits (86), Expect = 0.012 Identities = 18/49 (36%), Positives = 26/49 (53%) Frame = -1 Query: 416 ALDSFKXESEFELNLSVGDIVIVRKISSNGWAEGECKGKAGWFPHAYVE 270 A+ + + + EL+ G I+ V K + +GW EG C G FP YVE Sbjct: 425 AIYDYTKDKDDELSFKEGAIIYVIKKNDDGWFEGVCNRVTGLFPGNYVE 473
>YKA7_CAEEL (P34258) Hypothetical protein B0303.7| Length = 493 Score = 37.7 bits (86), Expect = 0.012 Identities = 16/49 (32%), Positives = 27/49 (55%) Frame = -1 Query: 416 ALDSFKXESEFELNLSVGDIVIVRKISSNGWAEGECKGKAGWFPHAYVE 270 A+ + +LN +VG ++V + W EGEC G++G FP +V+ Sbjct: 278 AIYDYNSNEAGDLNFAVGSQIMVTARVNEEWLEGECFGRSGIFPSQFVD 326
>CDC25_CANAL (P43069) Cell division control protein 25| Length = 1333 Score = 37.4 bits (85), Expect = 0.016 Identities = 20/53 (37%), Positives = 26/53 (49%), Gaps = 5/53 (9%) Frame = -1 Query: 416 ALDSFKXESEFELNLSVGDIVIVRKISSNGWAEGECKGKA-----GWFPHAYV 273 AL F L L++GD + V S+ GW +G G + GWFPH YV Sbjct: 37 ALYDFPGTQSSHLPLNLGDTIHVLSKSATGWWDGVVMGNSGELQRGWFPHNYV 89
>ABI1_HUMAN (Q8IZP0) Abl interactor 1 (Abelson interactor 1) (Abi-1) (Spectrin| SH3 domain-binding protein 1) (Eps8 SH3 domain-binding protein) (Eps8-binding protein) (e3B1) (Nap1-binding protein) (Nap1BP) (Abl-binding protein 4) (AblBP4) Length = 507 Score = 37.4 bits (85), Expect = 0.016 Identities = 18/49 (36%), Positives = 26/49 (53%) Frame = -1 Query: 416 ALDSFKXESEFELNLSVGDIVIVRKISSNGWAEGECKGKAGWFPHAYVE 270 A+ + + + EL+ G I+ V K + +GW EG C G FP YVE Sbjct: 452 AIYDYTKDKDDELSFMEGAIIYVIKKNDDGWYEGVCNRVTGLFPGNYVE 500
>GRB2_RAT (P62994) Growth factor receptor-bound protein 2 (Adapter protein| GRB2) (SH2/SH3 adapter GRB2) (Protein Ash) Length = 217 Score = 37.4 bits (85), Expect = 0.016 Identities = 18/49 (36%), Positives = 24/49 (48%) Frame = -1 Query: 419 EALDSFKXESEFELNLSVGDIVIVRKISSNGWAEGECKGKAGWFPHAYV 273 +AL F + + EL GD + V S W +G C G+ G FP YV Sbjct: 162 QALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYV 210
>GRB2_PONPY (Q5R4J7) Growth factor receptor-bound protein 2 (Adapter protein| GRB2) (SH2/SH3 adapter GRB2) Length = 217 Score = 37.4 bits (85), Expect = 0.016 Identities = 18/49 (36%), Positives = 24/49 (48%) Frame = -1 Query: 419 EALDSFKXESEFELNLSVGDIVIVRKISSNGWAEGECKGKAGWFPHAYV 273 +AL F + + EL GD + V S W +G C G+ G FP YV Sbjct: 162 QALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYV 210
>GRB2_MOUSE (Q60631) Growth factor receptor-bound protein 2 (Adapter protein| GRB2) (SH2/SH3 adapter GRB2) Length = 217 Score = 37.4 bits (85), Expect = 0.016 Identities = 18/49 (36%), Positives = 24/49 (48%) Frame = -1 Query: 419 EALDSFKXESEFELNLSVGDIVIVRKISSNGWAEGECKGKAGWFPHAYV 273 +AL F + + EL GD + V S W +G C G+ G FP YV Sbjct: 162 QALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYV 210
>GRB2_HUMAN (P62993) Growth factor receptor-bound protein 2 (Adapter protein| GRB2) (SH2/SH3 adapter GRB2) (Protein Ash) Length = 217 Score = 37.4 bits (85), Expect = 0.016 Identities = 18/49 (36%), Positives = 24/49 (48%) Frame = -1 Query: 419 EALDSFKXESEFELNLSVGDIVIVRKISSNGWAEGECKGKAGWFPHAYV 273 +AL F + + EL GD + V S W +G C G+ G FP YV Sbjct: 162 QALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYV 210
>SH3G2_MOUSE (Q62420) SH3-containing GRB2-like protein 2 (EC 2.3.1.-) (SH3| domain protein 2A) (Endophilin 1) (SH3p4) Length = 352 Score = 37.4 bits (85), Expect = 0.016 Identities = 19/49 (38%), Positives = 26/49 (53%) Frame = -1 Query: 416 ALDSFKXESEFELNLSVGDIVIVRKISSNGWAEGECKGKAGWFPHAYVE 270 AL + E+E EL GDI+ + W EG G++G+FP YVE Sbjct: 297 ALYDLEPENEGELAFKEGDIITLTNQIDENWYEGMLHGQSGFFPINYVE 345
>SHAN3_RAT (Q9JLU4) SH3 and multiple ankyrin repeat domains 3 (Shank3)| (Proline-rich synapse associated protein 2) (ProSAP2) (SPANK-2) Length = 1815 Score = 37.0 bits (84), Expect = 0.021 Identities = 19/49 (38%), Positives = 26/49 (53%) Frame = -1 Query: 416 ALDSFKXESEFELNLSVGDIVIVRKISSNGWAEGECKGKAGWFPHAYVE 270 A+ + + E E+ L G+ V V I G+ EG KG+ GWFP VE Sbjct: 552 AVKAHSPQGEGEIPLHRGEAVKVLSIGEGGFWEGTVKGRTGWFPADCVE 600
>CRKL_MOUSE (P47941) Crk-like protein| Length = 303 Score = 37.0 bits (84), Expect = 0.021 Identities = 18/37 (48%), Positives = 24/37 (64%) Frame = -1 Query: 380 LNLSVGDIVIVRKISSNGWAEGECKGKAGWFPHAYVE 270 L L VGDIV V +++ NG EGE G+ G FP +V+ Sbjct: 256 LALEVGDIVKVTRMNINGQWEGEVNGRKGLFPFTHVK 292
>CRKL_HUMAN (P46109) Crk-like protein| Length = 303 Score = 37.0 bits (84), Expect = 0.021 Identities = 18/37 (48%), Positives = 24/37 (64%) Frame = -1 Query: 380 LNLSVGDIVIVRKISSNGWAEGECKGKAGWFPHAYVE 270 L L VGDIV V +++ NG EGE G+ G FP +V+ Sbjct: 256 LALEVGDIVKVTRMNINGQWEGEVNGRKGLFPFTHVK 292
>HCLS1_MOUSE (P49710) Hematopoietic lineage cell-specific protein (Hematopoietic| cell-specific LYN substrate 1) (LckBP1) Length = 486 Score = 37.0 bits (84), Expect = 0.021 Identities = 17/49 (34%), Positives = 26/49 (53%) Frame = -1 Query: 416 ALDSFKXESEFELNLSVGDIVIVRKISSNGWAEGECKGKAGWFPHAYVE 270 AL ++ E EL+ DI+ ++ GW G+C+G G FP YV+ Sbjct: 436 ALYDYQGEGSDELSFDPDDIITDIEMVDEGWWRGQCRGHFGLFPANYVK 484
>CRK_HUMAN (P46108) Proto-oncogene C-crk (P38) (Adapter molecule crk)| Length = 304 Score = 37.0 bits (84), Expect = 0.021 Identities = 18/36 (50%), Positives = 23/36 (63%) Frame = -1 Query: 380 LNLSVGDIVIVRKISSNGWAEGECKGKAGWFPHAYV 273 L L VG++V V KI+ +G EG C GK G FP +V Sbjct: 256 LALEVGELVKVTKINVSGQWEGGCNGKRGHFPFTHV 291 Score = 31.6 bits (70), Expect = 0.87 Identities = 20/58 (34%), Positives = 26/58 (44%), Gaps = 1/58 (1%) Frame = -1 Query: 416 ALDSFKXESEFELNLSVGDIVIVR-KISSNGWAEGECKGKAGWFPHAYVERRERVLAS 246 AL F E +L GDI+ +R K W + +GK G P YVE+ AS Sbjct: 139 ALFDFNGNDEEDLPFKKGDILRIRDKPEEQWWNAEDSEGKRGMIPVPYVEKYRPASAS 196
>ABI3_HUMAN (Q9P2A4) ABI gene family member 3 (New molecule including SH3)| (Nesh) Length = 366 Score = 36.6 bits (83), Expect = 0.027 Identities = 16/45 (35%), Positives = 25/45 (55%) Frame = -1 Query: 404 FKXESEFELNLSVGDIVIVRKISSNGWAEGECKGKAGWFPHAYVE 270 + + + EL+ S G ++ V + S+GW EG G+FP YVE Sbjct: 319 YTSQKDNELSFSEGTVICVTRRYSDGWCEGVSSEGTGFFPGNYVE 363
>GRB2_XENTR (Q66II3) Growth factor receptor-bound protein 2 (Adapter protein| GRB2) (SH2/SH3 adapter GRB2) Length = 229 Score = 36.2 bits (82), Expect = 0.035 Identities = 18/49 (36%), Positives = 24/49 (48%) Frame = -1 Query: 419 EALDSFKXESEFELNLSVGDIVIVRKISSNGWAEGECKGKAGWFPHAYV 273 +AL F + + EL GD + V S W +G C G+ G FP YV Sbjct: 174 QALFDFDPQEDGELGFRRGDFIQVVDNSDPNWWKGTCLGQTGMFPRNYV 222
>GRB2B_XENLA (Q6GPJ9) Growth factor receptor-bound protein 2-B (Adapter protein| GRB2-B) (SH2/SH3 adapter GRB2-B) Length = 229 Score = 36.2 bits (82), Expect = 0.035 Identities = 18/49 (36%), Positives = 24/49 (48%) Frame = -1 Query: 419 EALDSFKXESEFELNLSVGDIVIVRKISSNGWAEGECKGKAGWFPHAYV 273 +AL F + + EL GD + V S W +G C G+ G FP YV Sbjct: 174 QALFDFDPQEDGELGFRRGDFIQVVDNSDPNWWKGTCLGQTGMFPRNYV 222
>CSH3_SCHPO (O43125) Protein csh3| Length = 296 Score = 36.2 bits (82), Expect = 0.035 Identities = 18/52 (34%), Positives = 25/52 (48%) Frame = -1 Query: 416 ALDSFKXESEFELNLSVGDIVIVRKISSNGWAEGECKGKAGWFPHAYVERRE 261 A+ F +L G+++IV + +N W GE GK G FP YV E Sbjct: 147 AMYDFPGPDAGDLGFHAGEVIIVLEHVNNDWWRGELNGKEGIFPSNYVRLLE 198
>OSTF1_HUMAN (Q92882) Osteoclast-stimulating factor 1| Length = 214 Score = 36.2 bits (82), Expect = 0.035 Identities = 17/48 (35%), Positives = 25/48 (52%) Frame = -1 Query: 416 ALDSFKXESEFELNLSVGDIVIVRKISSNGWAEGECKGKAGWFPHAYV 273 AL +F+ + EL GDI+ + +S W +G KG+ G P YV Sbjct: 19 ALYTFEPRTPDELYFEEGDIIYITDMSDTNWWKGTSKGRTGLIPSNYV 66
>NCF1_BOVIN (O77774) Neutrophil cytosol factor 1 (NCF-1) (Neutrophil NADPH| oxidase factor 1) (47 kDa neutrophil oxidase factor) (p47-phox) (NCF-47K) Length = 392 Score = 36.2 bits (82), Expect = 0.035 Identities = 16/49 (32%), Positives = 29/49 (59%) Frame = -1 Query: 416 ALDSFKXESEFELNLSVGDIVIVRKISSNGWAEGECKGKAGWFPHAYVE 270 A+ ++ S ++ L+ GD+V V + + +GW + K K GW P +Y+E Sbjct: 163 AIADYEKGSSSQMALATGDVVDVVEKNESGWWFCQMKTKRGWVPASYLE 211
>PPIP1_MOUSE (P97814) Proline-serine-threonine phosphatase-interacting protein 1| (PEST phosphatase-interacting protein 1) Length = 415 Score = 35.8 bits (81), Expect = 0.046 Identities = 17/50 (34%), Positives = 29/50 (58%) Frame = -1 Query: 416 ALDSFKXESEFELNLSVGDIVIVRKISSNGWAEGECKGKAGWFPHAYVER 267 AL + ++ EL++S GDI+ V +GW E G+ G+ P +Y+E+ Sbjct: 365 ALYDYTAQNSDELDISAGDILAVILEGEDGWWTVERNGQRGFVPGSYLEK 414
>PPIP1_HUMAN (O43586) Proline-serine-threonine phosphatase-interacting protein 1| (PEST phosphatase-interacting protein 1) (CD2-binding protein 1) (H-PIP) Length = 416 Score = 35.4 bits (80), Expect = 0.061 Identities = 18/50 (36%), Positives = 29/50 (58%) Frame = -1 Query: 416 ALDSFKXESEFELNLSVGDIVIVRKISSNGWAEGECKGKAGWFPHAYVER 267 AL + ++ EL+LS GDI+ V +GW E G+ G+ P +Y+E+ Sbjct: 366 ALYDYTAQNPDELDLSAGDILEVILEGEDGWWTVERNGQRGFVPGSYLEK 415
>ABI3_MOUSE (Q8BYZ1) ABI gene family member 3 (New molecule including SH3)| (Nesh) Length = 367 Score = 35.4 bits (80), Expect = 0.061 Identities = 16/45 (35%), Positives = 25/45 (55%) Frame = -1 Query: 404 FKXESEFELNLSVGDIVIVRKISSNGWAEGECKGKAGWFPHAYVE 270 + + + EL+ S G ++ V + S+GW EG G+FP YVE Sbjct: 320 YTRQKDNELSFSEGTVICVIRRYSDGWCEGVSSEGTGFFPGNYVE 364
>YG3D_YEAST (P53281) Protein YGR136W| Length = 241 Score = 35.4 bits (80), Expect = 0.061 Identities = 18/50 (36%), Positives = 27/50 (54%) Frame = -1 Query: 419 EALDSFKXESEFELNLSVGDIVIVRKISSNGWAEGECKGKAGWFPHAYVE 270 EAL F+ + + +L+L GD + V + S W G+ K G FP YV+ Sbjct: 59 EALYDFEAQQDGDLSLKTGDKIQVLEKISPDWYRGKSNNKIGIFPANYVK 108
>LSB3_YEAST (P43603) LAS seventeen-binding protein 3 (LAS17-binding protein 3)| Length = 451 Score = 35.0 bits (79), Expect = 0.079 Identities = 20/51 (39%), Positives = 25/51 (49%), Gaps = 2/51 (3%) Frame = -1 Query: 416 ALDSFKXESEFELNLSVGDIVIVRKISS--NGWAEGECKGKAGWFPHAYVE 270 AL SF E +L GD++ + K S N W G G+ G FP YVE Sbjct: 399 ALYSFAGEESGDLPFRKGDVITILKKSDSQNDWWTGRVNGREGIFPANYVE 449
>HCLS1_HUMAN (P14317) Hematopoietic lineage cell-specific protein (Hematopoietic| cell-specific LYN substrate 1) (LckBP1) (p75) Length = 486 Score = 35.0 bits (79), Expect = 0.079 Identities = 17/52 (32%), Positives = 25/52 (48%) Frame = -1 Query: 416 ALDSFKXESEFELNLSVGDIVIVRKISSNGWAEGECKGKAGWFPHAYVERRE 261 AL ++ E EL+ D++ ++ GW G C G G FP YV+ E Sbjct: 435 ALYDYQGEGSDELSFDPDDVITDIEMVDEGWWRGRCHGHFGLFPANYVKLLE 486
>GRAP_MOUSE (Q9CX99) GRB2-related adapter protein| Length = 217 Score = 34.7 bits (78), Expect = 0.10 Identities = 17/50 (34%), Positives = 26/50 (52%) Frame = -1 Query: 419 EALDSFKXESEFELNLSVGDIVIVRKISSNGWAEGECKGKAGWFPHAYVE 270 +A F + +L+L GDIV V + W G G+ G+FP +YV+ Sbjct: 164 QAQFDFSAQDPSQLSLRRGDIVEVVEREDPHWWRGRAGGRLGFFPRSYVQ 213
>STAC_HUMAN (Q99469) SH3 and cysteine-rich domain-containing protein (SRC| homology 3 and cysteine-rich domain protein) Length = 402 Score = 34.3 bits (77), Expect = 0.13 Identities = 15/53 (28%), Positives = 31/53 (58%) Frame = -1 Query: 416 ALDSFKXESEFELNLSVGDIVIVRKISSNGWAEGECKGKAGWFPHAYVERRER 258 AL F + +L + GDI+ + + S+ W +G+ + + G+FP +V+R ++ Sbjct: 292 ALYKFVPQENEDLEMRPGDIITLLEDSNEDWWKGKIQDRIGFFPANFVQRLQQ 344
>RHG26_HUMAN (Q9UNA1) Rho-GTPase-activating protein 26 (Oligophrenin-1-like| protein) (GTPase regulator associated with focal adhesion kinase) Length = 814 Score = 34.3 bits (77), Expect = 0.13 Identities = 19/51 (37%), Positives = 25/51 (49%), Gaps = 1/51 (1%) Frame = -1 Query: 419 EALDSFKXESEFELNLSVGDIVI-VRKISSNGWAEGECKGKAGWFPHAYVE 270 +AL + K E + EL+ + G + V GW EG GK G P YVE Sbjct: 762 KALYACKAEHDSELSFTAGTVFDNVHPSQEPGWLEGTLNGKTGLIPENYVE 812
>MYO1F_MOUSE (P70248) Myosin If| Length = 1099 Score = 34.3 bits (77), Expect = 0.13 Identities = 16/50 (32%), Positives = 28/50 (56%) Frame = -1 Query: 416 ALDSFKXESEFELNLSVGDIVIVRKISSNGWAEGECKGKAGWFPHAYVER 267 AL + + EL+ +V +++ + S+GW +G G+ G FP YVE+ Sbjct: 1049 ALYQYIGQDVDELSFNVNEVIEILIEDSSGWWKGRLHGQEGLFPGNYVEK 1098
>APP1_SCHPO (Q9P7E8) Protein app1| Length = 857 Score = 33.9 bits (76), Expect = 0.18 Identities = 16/50 (32%), Positives = 25/50 (50%) Frame = -1 Query: 419 EALDSFKXESEFELNLSVGDIVIVRKISSNGWAEGECKGKAGWFPHAYVE 270 +A+ ++ + + EL+ +I+ W EGEC G G FP YVE Sbjct: 806 KAIYDYQAQEDNELSFFEDEIIANVDCVDPNWWEGECHGHRGLFPSNYVE 855 Score = 29.6 bits (65), Expect = 3.3 Identities = 16/46 (34%), Positives = 24/46 (52%), Gaps = 1/46 (2%) Frame = -1 Query: 404 FKXESEFELNLSVGDIVIVRKISSNGWAEGE-CKGKAGWFPHAYVE 270 + E E E+ L + + + + +GW GE KG+ G FP YVE Sbjct: 736 YSPEEENEIELVENEQIQILEFVDDGWWLGENSKGQQGLFPSNYVE 781
>GRB2A_XENLA (P87379) Growth factor receptor-bound protein 2-A (Adapter protein| GRB2-A) (SH2/SH3 adapter GRB2-A) Length = 229 Score = 33.9 bits (76), Expect = 0.18 Identities = 17/49 (34%), Positives = 23/49 (46%) Frame = -1 Query: 419 EALDSFKXESEFELNLSVGDIVIVRKISSNGWAEGECKGKAGWFPHAYV 273 +AL F + + EL GD + V S W +G C + G FP YV Sbjct: 174 QALFDFDPQEDGELGFRRGDFIQVVDNSDPNWWKGTCLSQTGMFPRNYV 222
>MYO1F_HUMAN (O00160) Myosin If (Myosin-IE)| Length = 1098 Score = 33.5 bits (75), Expect = 0.23 Identities = 15/50 (30%), Positives = 27/50 (54%) Frame = -1 Query: 416 ALDSFKXESEFELNLSVGDIVIVRKISSNGWAEGECKGKAGWFPHAYVER 267 AL + + EL+ +V +++ + +GW +G G+ G FP YVE+ Sbjct: 1048 ALYQYVGQDVDELSFNVNEVIEILMEDPSGWWKGRLHGQEGLFPGNYVEK 1097
>STAC_MOUSE (P97306) SH3 and cysteine-rich domain-containing protein (SRC| homology 3 and cysteine-rich domain protein) Length = 403 Score = 33.1 bits (74), Expect = 0.30 Identities = 15/52 (28%), Positives = 30/52 (57%) Frame = -1 Query: 416 ALDSFKXESEFELNLSVGDIVIVRKISSNGWAEGECKGKAGWFPHAYVERRE 261 AL F + +L + GD++ + + S+ W +G+ + + G+FP +V+R E Sbjct: 293 ALYRFIPQENEDLEMRPGDMITLLEDSNEDWWKGKIQDRVGFFPANFVQRVE 344
>STAM2_RAT (Q5XHY7) Signal transducing adapter molecule 2 (STAM-2)| Length = 523 Score = 32.7 bits (73), Expect = 0.39 Identities = 18/48 (37%), Positives = 24/48 (50%) Frame = -1 Query: 416 ALDSFKXESEFELNLSVGDIVIVRKISSNGWAEGECKGKAGWFPHAYV 273 AL F+ + EL G+I+ V S W EGE AG FP ++V Sbjct: 209 ALYDFEAVEDNELTFKHGEIITVLDDSDANWWEGENHRGAGLFPSSFV 256
>ARHG4_HUMAN (Q9NR80) Rho guanine nucleotide exchange factor 4 (APC-stimulated| guanine nucleotide exchange factor) (Asef) Length = 657 Score = 32.3 bits (72), Expect = 0.51 Identities = 16/52 (30%), Positives = 23/52 (44%) Frame = -1 Query: 419 EALDSFKXESEFELNLSVGDIVIVRKISSNGWAEGECKGKAGWFPHAYVERR 264 EAL + EL GD++ V ++ W G GWFP ++V R Sbjct: 167 EALWDHVTMDDQELGFKAGDVIEVMDATNREWWWGRVADGEGWFPASFVRLR 218
>MYO5_YEAST (Q04439) Myosin-5| Length = 1219 Score = 32.3 bits (72), Expect = 0.51 Identities = 15/43 (34%), Positives = 24/43 (55%), Gaps = 2/43 (4%) Frame = -1 Query: 392 SEFELNLSVGDIVIVRKISSNGWAEGEC--KGKAGWFPHAYVE 270 S EL L GD++ + + +GW+ G+ K GW P AY++ Sbjct: 1101 SPSELPLKKGDVIYITREEPSGWSLGKLLDGSKEGWVPTAYMK 1143
>GRAP_HUMAN (Q13588) GRB2-related adapter protein| Length = 217 Score = 32.3 bits (72), Expect = 0.51 Identities = 15/50 (30%), Positives = 25/50 (50%) Frame = -1 Query: 419 EALDSFKXESEFELNLSVGDIVIVRKISSNGWAEGECKGKAGWFPHAYVE 270 +A F + +L+ GDI+ V + W G G+ G+FP +YV+ Sbjct: 164 QAQFDFSAQDPSQLSFRRGDIIEVLERPDPHWWRGRSCGRVGFFPRSYVQ 213
>RHG04_HUMAN (P98171) Rho-GTPase-activating protein 4 (Rho-GAP hematopoietic| protein C1) (p115) Length = 946 Score = 32.0 bits (71), Expect = 0.67 Identities = 13/37 (35%), Positives = 21/37 (56%) Frame = -1 Query: 383 ELNLSVGDIVIVRKISSNGWAEGECKGKAGWFPHAYV 273 EL+ GD++ + + +S+ W GE G G PH Y+ Sbjct: 764 ELSFRRGDVLRLHERASSDWWRGEHNGMRGLIPHKYI 800
>M3KSL_DROME (Q95UN8) Mitogen-activated protein kinase kinase kinase (EC| 2.7.11.25) (Mixed lineage kinase) (dMLK) (Protein slipper) Length = 1161 Score = 31.6 bits (70), Expect = 0.87 Identities = 20/56 (35%), Positives = 26/56 (46%), Gaps = 5/56 (8%) Frame = -1 Query: 425 LGEALDSFKXESEFELNLSVGDIVIVRKISSN-----GWAEGECKGKAGWFPHAYV 273 L AL + + E EL L G+IV+V S GW G+ K G FP +V Sbjct: 60 LWTALYDYDAQGEDELTLRRGEIVVVLSTDSEVSGDVGWWTGKIGDKVGVFPKDFV 115
>MYO3_YEAST (P36006) Myosin-3| Length = 1273 Score = 31.2 bits (69), Expect = 1.1 Identities = 16/42 (38%), Positives = 22/42 (52%), Gaps = 2/42 (4%) Frame = -1 Query: 392 SEFELNLSVGDIVIVRKISSNGWAEGEC--KGKAGWFPHAYV 273 S EL L GDIV + + +GW+ + K GW P AY+ Sbjct: 1137 SSSELPLKKGDIVFISRDEPSGWSLAKLLDGSKEGWVPTAYM 1178
>SEM5_CAEEL (P29355) Sex muscle abnormal protein 5| Length = 228 Score = 31.2 bits (69), Expect = 1.1 Identities = 15/49 (30%), Positives = 22/49 (44%) Frame = -1 Query: 419 EALDSFKXESEFELNLSVGDIVIVRKISSNGWAEGECKGKAGWFPHAYV 273 +AL F + EL GD++ + W EG+ + G FP YV Sbjct: 160 QALFDFNPQESGELAFKRGDVITLINKDDPNWWEGQLNNRRGIFPSNYV 208
>ARHGG_MOUSE (Q3U5C8) Rho guanine nucleotide exchange factor 16| Length = 713 Score = 31.2 bits (69), Expect = 1.1 Identities = 16/50 (32%), Positives = 26/50 (52%), Gaps = 2/50 (4%) Frame = -1 Query: 419 EALDSFKXESEFELNLSVGDIVIVRKISSNGWAEGEC--KGKAGWFPHAY 276 E ++ + E+ L DIV+V + +GW GE G+ GWFP ++ Sbjct: 639 EVTKAYFAKQADEITLQQADIVLVLQ-EEDGWLHGERLRDGETGWFPESF 687
>M3K9_HUMAN (P80192) Mitogen-activated protein kinase kinase kinase 9 (EC| 2.7.11.25) (Mixed lineage kinase 1) Length = 1104 Score = 31.2 bits (69), Expect = 1.1 Identities = 19/56 (33%), Positives = 26/56 (46%), Gaps = 5/56 (8%) Frame = -1 Query: 416 ALDSFKXESEFELNLSVGDIVIVRKISSN-----GWAEGECKGKAGWFPHAYVERR 264 A+ ++ E EL L +GD+V V S GW G+ + G FP YV R Sbjct: 59 AVFEYEAAGEDELTLRLGDVVEVLSKDSQVSGDEGWWTGQLNQRVGIFPSNYVTPR 114
>JIP1_DROME (Q9W0K0) JNK-interacting protein 1 (JIP-1) (Protein eye| developmental SP512) (APP-like-interacting protein 1) (APLIP1) Length = 490 Score = 31.2 bits (69), Expect = 1.1 Identities = 17/48 (35%), Positives = 24/48 (50%), Gaps = 2/48 (4%) Frame = -1 Query: 413 LDSFKXESEFELNLSVGDIVIVRKISSNGWAEGE--CKGKAGWFPHAY 276 L F E+ L +GD + V+K + + W EG G+ G FP AY Sbjct: 279 LHKFVPRHHDEIELEIGDAIYVQKEAEDLWCEGVNLRTGRQGIFPSAY 326
>ARHG4_MOUSE (Q7TNR9) Rho guanine nucleotide exchange factor 4 (APC-stimulated| guanine nucleotide exchange factor) (Asef) Length = 484 Score = 31.2 bits (69), Expect = 1.1 Identities = 13/40 (32%), Positives = 19/40 (47%) Frame = -1 Query: 383 ELNLSVGDIVIVRKISSNGWAEGECKGKAGWFPHAYVERR 264 EL GD++ V ++ W G GWFP ++V R Sbjct: 5 ELGFKAGDVIEVMDATNREWWWGRVADGEGWFPASFVRLR 44
>SPTA2_RAT (P16086) Spectrin alpha chain, brain (Spectrin, non-erythroid alpha| chain) (Alpha-II spectrin) (Fodrin alpha chain) Length = 2472 Score = 30.8 bits (68), Expect = 1.5 Identities = 14/50 (28%), Positives = 28/50 (56%) Frame = -1 Query: 416 ALDSFKXESEFELNLSVGDIVIVRKISSNGWAEGECKGKAGWFPHAYVER 267 AL ++ +S E+ + GDI+ + ++ W + E + G+ P AYV++ Sbjct: 974 ALYDYQEKSPREVTMKKGDILTLLNSTNKDWWKVEVNDRQGFVPAAYVKK 1023
>SPTA2_HUMAN (Q13813) Spectrin alpha chain, brain (Spectrin, non-erythroid alpha| chain) (Alpha-II spectrin) (Fodrin alpha chain) Length = 2472 Score = 30.8 bits (68), Expect = 1.5 Identities = 14/50 (28%), Positives = 28/50 (56%) Frame = -1 Query: 416 ALDSFKXESEFELNLSVGDIVIVRKISSNGWAEGECKGKAGWFPHAYVER 267 AL ++ +S E+ + GDI+ + ++ W + E + G+ P AYV++ Sbjct: 974 ALYDYQEKSPREVTMKKGDILTLLNSTNKDWWKVEVNDRQGFVPAAYVKK 1023
>SPTA2_CHICK (P07751) Spectrin alpha chain, brain (Spectrin, non-erythroid alpha| chain) (Fodrin alpha chain) Length = 2477 Score = 30.8 bits (68), Expect = 1.5 Identities = 14/50 (28%), Positives = 28/50 (56%) Frame = -1 Query: 416 ALDSFKXESEFELNLSVGDIVIVRKISSNGWAEGECKGKAGWFPHAYVER 267 AL ++ +S E+ + GDI+ + ++ W + E + G+ P AYV++ Sbjct: 974 ALYDYQEKSPREVTMKKGDILTLLNSTNKDWWKVEVNDRQGFVPAAYVKK 1023
>STAC3_XENTR (Q68F99) SH3 and cysteine-rich domain-containing protein 3| Length = 337 Score = 30.8 bits (68), Expect = 1.5 Identities = 16/50 (32%), Positives = 26/50 (52%) Frame = -1 Query: 416 ALDSFKXESEFELNLSVGDIVIVRKISSNGWAEGECKGKAGWFPHAYVER 267 AL FK + +L+ G+ + V S+ W G+ KAG+FP ++ R Sbjct: 227 ALYRFKALEKDDLDFQAGERITVIDDSNEEWWRGKVGEKAGYFPANFIIR 276
>CDC15_SCHPO (Q09822) Cell division control protein 15| Length = 927 Score = 30.0 bits (66), Expect = 2.5 Identities = 15/53 (28%), Positives = 27/53 (50%), Gaps = 4/53 (7%) Frame = -1 Query: 416 ALDSFKXESEFELNLSVGDIVIVRKISSNGWAEGEC----KGKAGWFPHAYVE 270 AL ++ + E++ GD ++V + +GW +GE K G FP +V+ Sbjct: 873 ALYDYQAQIPEEISFQKGDTLMVLRTQEDGWWDGEIINVPNSKRGLFPSNFVQ 925
>STAM2_HUMAN (O75886) Signal transducing adapter molecule 2 (STAM-2)| Length = 525 Score = 30.0 bits (66), Expect = 2.5 Identities = 17/48 (35%), Positives = 23/48 (47%) Frame = -1 Query: 416 ALDSFKXESEFELNLSVGDIVIVRKISSNGWAEGECKGKAGWFPHAYV 273 AL F+ + EL G+I+IV S W +GE G FP +V Sbjct: 209 ALYDFEAVEDNELTFKHGEIIIVLDDSDANWWKGENHRGIGLFPSNFV 256
>SPTCA_DROME (P13395) Spectrin alpha chain| Length = 2415 Score = 30.0 bits (66), Expect = 2.5 Identities = 13/57 (22%), Positives = 32/57 (56%) Frame = -1 Query: 416 ALDSFKXESEFELNLSVGDIVIVRKISSNGWAEGECKGKAGWFPHAYVERRERVLAS 246 AL + +S E+++ GD++ + ++ W + E + G+ P AY+++ + L++ Sbjct: 977 ALYDYTEKSPREVSMKKGDVLTLLNSNNKDWWKVEVNDRQGFVPAAYIKKIDAGLSA 1033
>STAM1_MOUSE (P70297) Signal transducing adapter molecule 1 (STAM-1)| Length = 547 Score = 29.6 bits (65), Expect = 3.3 Identities = 15/48 (31%), Positives = 22/48 (45%) Frame = -1 Query: 416 ALDSFKXESEFELNLSVGDIVIVRKISSNGWAEGECKGKAGWFPHAYV 273 A+ F+ + EL G+I+ V S W +GE G FP +V Sbjct: 216 AVYDFEAAEDNELTFKAGEIITVLDDSDPNWWKGETHQGVGLFPSNFV 263
>STAM1_HUMAN (Q92783) Signal transducing adapter molecule 1 (STAM-1)| Length = 539 Score = 29.6 bits (65), Expect = 3.3 Identities = 15/48 (31%), Positives = 22/48 (45%) Frame = -1 Query: 416 ALDSFKXESEFELNLSVGDIVIVRKISSNGWAEGECKGKAGWFPHAYV 273 A+ F+ + EL G+I+ V S W +GE G FP +V Sbjct: 216 AIYDFEAAEDNELTFKAGEIITVLDDSDPNWWKGETHQGIGLFPSNFV 263
>STAM2_CHICK (O93436) Signal transducing adapter molecule 2 (STAM-2) (Epidermal| growth factor receptor-associated protein with SH3 and TAM domain) Length = 468 Score = 29.6 bits (65), Expect = 3.3 Identities = 16/48 (33%), Positives = 22/48 (45%) Frame = -1 Query: 416 ALDSFKXESEFELNLSVGDIVIVRKISSNGWAEGECKGKAGWFPHAYV 273 AL F+ + EL G+I+ V S W +GE G FP +V Sbjct: 208 ALYDFEAVEDNELTFKSGEIIFVLDDSDTDWWKGENHRGVGLFPSNFV 255
>MYO1_SCHPO (Q9Y7Z8) Myosin-1| Length = 1217 Score = 29.3 bits (64), Expect = 4.3 Identities = 17/54 (31%), Positives = 25/54 (46%) Frame = -1 Query: 434 DLFLGEALDSFKXESEFELNLSVGDIVIVRKISSNGWAEGECKGKAGWFPHAYV 273 DL+L AL F S E+ + +I+ + + +GW G GW P YV Sbjct: 1109 DLYL--ALYDFAGRSPNEMTIKKDEIIEIVQKEPSGWWLALKNGAEGWVPATYV 1160
>ABL1_HUMAN (P00519) Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2)| (p150) (c-ABL) (Abelson murine leukemia viral oncogene homolog 1) Length = 1130 Score = 29.3 bits (64), Expect = 4.3 Identities = 15/49 (30%), Positives = 24/49 (48%), Gaps = 1/49 (2%) Frame = -1 Query: 416 ALDSFKXESEFELNLSVGDIVIVRKISSNG-WAEGECKGKAGWFPHAYV 273 AL F + L+++ G+ + V + NG W E + K GW P Y+ Sbjct: 68 ALYDFVASGDNTLSITKGEKLRVLGYNHNGEWCEAQTKNGQGWVPSNYI 116
>ABL1_MOUSE (P00520) Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2)| (p150) (c-ABL) (Abelson murine leukemia viral oncogene homolog 1) Length = 1123 Score = 29.3 bits (64), Expect = 4.3 Identities = 15/49 (30%), Positives = 24/49 (48%), Gaps = 1/49 (2%) Frame = -1 Query: 416 ALDSFKXESEFELNLSVGDIVIVRKISSNG-WAEGECKGKAGWFPHAYV 273 AL F + L+++ G+ + V + NG W E + K GW P Y+ Sbjct: 68 ALYDFVASGDNTLSITKGEKLRVLGYNHNGEWCEAQTKNGQGWVPSNYI 116
>AMPH_CHICK (P50478) Amphiphysin| Length = 682 Score = 29.3 bits (64), Expect = 4.3 Identities = 21/47 (44%), Positives = 25/47 (53%) Frame = -1 Query: 431 LFLGEALDSFKXESEFELNLSVGDIVIVRKISSNGWAEGECKGKAGW 291 LF E L F+ + ELNL GDIV+V I S A+ E AGW Sbjct: 611 LFKVEVLHDFEAANSDELNLKRGDIVLV--IPSETTADQE----AGW 651
>ABL_FSVHY (P10447) Tyrosine-protein kinase transforming protein Abl (EC| 2.7.10.2) (V-abl) Length = 439 Score = 29.3 bits (64), Expect = 4.3 Identities = 15/49 (30%), Positives = 24/49 (48%), Gaps = 1/49 (2%) Frame = -1 Query: 416 ALDSFKXESEFELNLSVGDIVIVRKISSNG-WAEGECKGKAGWFPHAYV 273 AL F + L+++ G+ + V + NG W E + K GW P Y+ Sbjct: 17 ALYDFVASGDNTLSITKGEKLRVLGYNHNGEWCEAQTKNGQGWVPSNYI 65
>CSK_CHICK (P41239) Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase)| Length = 450 Score = 28.9 bits (63), Expect = 5.7 Identities = 17/55 (30%), Positives = 31/55 (56%), Gaps = 2/55 (3%) Frame = -1 Query: 407 SFKXESEFELNLSVGDIVIVRKISSN-GWAEGECK-GKAGWFPHAYVERRERVLA 249 +F +E +L S GD++ + ++ + W + + K G+ G P YV++RE V A Sbjct: 19 NFHGTAEQDLPFSKGDVLTIVAVTKDPNWYKAKNKVGREGIIPANYVQKREGVKA 73
>UAS3_DROME (Q9VCE9) Protein UBASH3A homolog| Length = 751 Score = 28.9 bits (63), Expect = 5.7 Identities = 18/45 (40%), Positives = 22/45 (48%), Gaps = 6/45 (13%) Frame = -1 Query: 383 ELNLSVGDIVIVRK----ISSNGWAEG--ECKGKAGWFPHAYVER 267 EL L +GD + + SS+GWAEG G G P Y ER Sbjct: 289 ELELRIGDYIYLNTEVVDSSSDGWAEGISWLTGSTGHLPVNYTER 333
>RBGPR_DROME (Q9VKB9) Rab3 GTPase-activating protein regulatory subunit| Length = 1341 Score = 28.9 bits (63), Expect = 5.7 Identities = 11/33 (33%), Positives = 19/33 (57%) Frame = -3 Query: 132 EFSPREPVFARMMYI*HFRTPNWRPKRALCCCL 34 + S + + A ++ + FRTP+W K +CC L Sbjct: 982 QLSSLDHLKAALLCLNQFRTPDWALKHGICCML 1014
>SDC25_YEAST (P14771) Guanine nucleotide exchange factor SDC25| Length = 1252 Score = 28.9 bits (63), Expect = 5.7 Identities = 17/60 (28%), Positives = 27/60 (45%), Gaps = 12/60 (20%) Frame = -1 Query: 419 EALDSFKXESEFELNLSVGDIVIVRKISSNGWAEGECKGKA------------GWFPHAY 276 E + +S +L+L VGD++ V SNGW +G + GWFP ++ Sbjct: 32 ECTYQYFTKSRNKLSLRVGDLIYVLTKGSNGWWDGVLIRHSANNNNNSLILDRGWFPPSF 91
>VAV_DROME (Q9NHV9) Protein vav (DroVav)| Length = 793 Score = 28.5 bits (62), Expect = 7.4 Identities = 16/50 (32%), Positives = 26/50 (52%) Frame = -1 Query: 392 SEFELNLSVGDIVIVRKISSNGWAEGECKGKAGWFPHAYVERRERVLASK 243 ++ +L +VI + S GW G+ G+FP YV+ E+ LAS+ Sbjct: 744 NQLQLRTDCQVLVIGKDGDSKGWWRGKIGDTVGYFPKEYVQ--EQKLASE 791
>M3K11_HUMAN (Q16584) Mitogen-activated protein kinase kinase kinase 11 (EC| 2.7.11.25) (Mixed lineage kinase 3) (Src-homology 3 domain-containing proline-rich kinase) Length = 847 Score = 28.5 bits (62), Expect = 7.4 Identities = 19/55 (34%), Positives = 25/55 (45%), Gaps = 5/55 (9%) Frame = -1 Query: 416 ALDSFKXESEFELNLSVGDIVIVRKISS-----NGWAEGECKGKAGWFPHAYVER 267 AL ++ + EL L GD V V + GW G+ G+ G FP YV R Sbjct: 48 ALFDYEPSGQDELALRKGDRVEVLSRDAAISGDEGWWAGQVGGQVGIFPSNYVSR 102
>ABL2_HUMAN (P42684) Tyrosine-protein kinase ABL2 (EC 2.7.10.2) (Abelson murine| leukemia viral oncogene homolog 2) (Tyrosine kinase ARG) Length = 1182 Score = 28.1 bits (61), Expect = 9.7 Identities = 15/49 (30%), Positives = 24/49 (48%), Gaps = 1/49 (2%) Frame = -1 Query: 416 ALDSFKXESEFELNLSVGDIVIVRKISSNG-WAEGECKGKAGWFPHAYV 273 AL F + L+++ G+ + V + NG W+E K GW P Y+ Sbjct: 114 ALYDFVASGDNTLSITKGEKLRVLGYNQNGEWSEVRSKNGQGWVPSNYI 162
>STAM2_MOUSE (O88811) Signal transducing adapter molecule 2 (STAM-2)| (Hrs-binding protein) Length = 523 Score = 28.1 bits (61), Expect = 9.7 Identities = 15/48 (31%), Positives = 22/48 (45%) Frame = -1 Query: 416 ALDSFKXESEFELNLSVGDIVIVRKISSNGWAEGECKGKAGWFPHAYV 273 AL F+ + EL G+++ V S W +GE G FP +V Sbjct: 209 ALYDFEAVEDNELTFKHGELITVLDDSDANWWQGENHRGTGLFPSNFV 256
>JHD1_CAEEL (Q95Q98) JmjC domain-containing histone demethylation protein 1 (EC| 1.14.11.-) Length = 1076 Score = 28.1 bits (61), Expect = 9.7 Identities = 27/87 (31%), Positives = 40/87 (45%), Gaps = 6/87 (6%) Frame = -2 Query: 421 ERPSIPSRXRVSLSSTYQLVTSLSSERYQATAGRKVN------AREKQDGSHMLTSKGAS 260 ++P + S VS ++ YQL +SSER + AG + A +QD + ++GAS Sbjct: 880 QKPKLSSPAMVSSTNEYQLRKHMSSERRSSDAGSAMKKGVYMPAMSRQD---KMIAEGAS 936 Query: 259 VFWRAKSRIFSRGFEEEHRL*VFDFNS 179 A S S E + DFNS Sbjct: 937 ----APSSRHSSISSERRPSFIPDFNS 959
>NPHP1_MOUSE (Q9QY53) Nephrocystin-1| Length = 687 Score = 28.1 bits (61), Expect = 9.7 Identities = 14/50 (28%), Positives = 22/50 (44%), Gaps = 1/50 (2%) Frame = -1 Query: 416 ALDSFKXESEFELNLSVGDIV-IVRKISSNGWAEGECKGKAGWFPHAYVE 270 AL F + +L GD++ I+ K W + +G G P Y+E Sbjct: 162 ALGDFAAQQTGDLTFKKGDVLHIIEKKPDGWWLAKDAEGVEGLIPRTYLE 211 Database: uniprot_sprot.fasta Posted date: May 25, 2006 5:36 PM Number of letters in database: 80,573,946 Number of sequences in database: 219,361 Lambda K H 0.318 0.135 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 61,399,068 Number of Sequences: 219361 Number of extensions: 1213244 Number of successful extensions: 2847 Number of sequences better than 10.0: 143 Number of HSP's better than 10.0 without gapping: 2748 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 2840 length of database: 80,573,946 effective HSP length: 101 effective length of database: 58,418,485 effective search space used: 2511994855 frameshift window, decay const: 50, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
