>SAP_CHICK (O13035) Proactivator polypeptide precursor [Contains: Saposin A;|
Saposin B; Saposin C; Saposin D]
Length = 518
Score = 45.4 bits (106), Expect = 1e-04
Identities = 31/123 (25%), Positives = 58/123 (47%), Gaps = 3/123 (2%)
Frame = -3
Query: 603 CRDNALLSGVRSESTCVFCHHLMDEVLSKLKDPDAEFEIIQILLKECKKI--EGHEQQCK 430
C+ N + C C L+ V LKD E EI L K C+ + +G +CK
Sbjct: 49 CQQNVWSKPAVNSIPCDLCKELVTVVGKVLKDNGTEDEIRSYLEKRCEFLPDQGLASECK 108
Query: 429 RLVLQYIPLIL-VNGEKFLEKNDICTIVQACDAGKKTVLGSFSEEGLLRDE*RQKDYTEP 253
+V Y+P+I+ + E+F + +C+ + C + +K + ++ L ++ + D++E
Sbjct: 109 EIVDSYLPVIMDMIKEEFDKPEVVCSALSLCQSLQKHLAAMKLQKQLQSNKIPELDFSEL 168
Query: 252 RKP 244
P
Sbjct: 169 TSP 171
Score = 37.0 bits (84), Expect = 0.047
Identities = 23/83 (27%), Positives = 39/83 (46%), Gaps = 1/83 (1%)
Frame = -3
Query: 558 CVFCHHLMDEVLSKLKDPDAEFEIIQILLKECKKI-EGHEQQCKRLVLQYIPLILVNGEK 382
C C ++ +L+ EI +L K C + E QC + V QY P+++ +
Sbjct: 403 CDICKMIVAYADKELEKNATTTEIEALLEKVCHFLPESVSDQCVQFVEQYEPVVVQLLAE 462
Query: 381 FLEKNDICTIVQACDAGKKTVLG 313
++ +CT + C A KK +LG
Sbjct: 463 MMDPTFVCTKLGVCGAAKKPLLG 485
>SAP_RAT (P10960) Sulfated glycoprotein 1 precursor (SGP-1) (Prosaposin)|
Length = 554
Score = 38.1 bits (87), Expect = 0.021
Identities = 21/84 (25%), Positives = 43/84 (51%), Gaps = 1/84 (1%)
Frame = -3
Query: 558 CVFCHHLMDEVLSKLKDPDAEFEIIQILLKECKKI-EGHEQQCKRLVLQYIPLILVNGEK 382
C C L+ + L+ + EI+ L K C + + +++QC V +Y PL+L +
Sbjct: 439 CEVCKKLVIYLEHNLEKNSTKEEILAALEKGCSFLPDPYQKQCDEFVAEYEPLLLEILVE 498
Query: 381 FLEKNDICTIVQACDAGKKTVLGS 310
++ + +C+ + C + K +LG+
Sbjct: 499 VMDPSFVCSKIGVCPSAYKLLLGT 522
Score = 37.0 bits (84), Expect = 0.047
Identities = 24/79 (30%), Positives = 37/79 (46%), Gaps = 4/79 (5%)
Frame = -3
Query: 558 CVFCHHLMDEVLSKLKDPDAEFEIIQILLKECKKIEGH--EQQCKRLVLQYIPLIL--VN 391
C C ++ E + LKD E EI+ L K C I CK +V Y+P+IL +
Sbjct: 63 CDICKTVVTEAGNLLKDNATEEEILHYLEKTCAWIHDSSLSASCKEVVDSYLPVILDMIK 122
Query: 390 GEKFLEKNDICTIVQACDA 334
GE ++C+ + C +
Sbjct: 123 GE-MSNPGEVCSALNLCQS 140
>SAP_HUMAN (P07602) Proactivator polypeptide precursor [Contains: Saposin A|
(Protein A); Saposin B-Val; Saposin B (Sphingolipid
activator protein 1) (SAP-1) (Cerebroside sulfate
activator) (CSAct) (Dispersin) (Sulfatide/GM1
activator); Saposin C (Co-beta-
Length = 524
Score = 38.1 bits (87), Expect = 0.021
Identities = 20/84 (23%), Positives = 44/84 (52%), Gaps = 1/84 (1%)
Frame = -3
Query: 558 CVFCHHLMDEVLSKLKDPDAEFEIIQILLKECKKI-EGHEQQCKRLVLQYIPLILVNGEK 382
C C L+ + L+ + EI+ L K C + + +++QC + V +Y P+++ +
Sbjct: 409 CEVCKKLVGYLDRNLEKNSTKQEILAALEKGCSFLPDPYQKQCDQFVAEYEPVLIEILVE 468
Query: 381 FLEKNDICTIVQACDAGKKTVLGS 310
++ + +C + AC + K +LG+
Sbjct: 469 VMDPSFVCLKIGACPSAHKPLLGT 492
Score = 36.2 bits (82), Expect = 0.080
Identities = 28/109 (25%), Positives = 49/109 (44%), Gaps = 4/109 (3%)
Frame = -3
Query: 558 CVFCHHLMDEVLSKLKDPDAEFEIIQILLKECKKI--EGHEQQCKRLVLQYIPLIL--VN 391
C C ++ LKD E EI+ L K C + CK +V Y+P+IL +
Sbjct: 63 CDICKDVVTAAGDMLKDNATEEEILVYLEKTCDWLPKPNMSASCKEIVDSYLPVILDIIK 122
Query: 390 GEKFLEKNDICTIVQACDAGKKTVLGSFSEEGLLRDE*RQKDYTEPRKP 244
GE ++C+ + C++ +K + ++ L ++ + D TE P
Sbjct: 123 GE-MSRPGEVCSALNLCESLQKHLAELNHQKQLESNKIPELDMTEVVAP 170
>SAP_BOVIN (P26779) Proactivator polypeptide precursor [Contains: Saposin A|
(Protein A); Saposin B (Sphingolipid activator protein
1) (SAP-1) (Cerebroside sulfate activator) (CSAct)
(Dispersin) (Sulfatide/GM1 activator); Saposin C
(Co-beta-glucosidase) (A
Length = 525
Score = 37.4 bits (85), Expect = 0.036
Identities = 20/84 (23%), Positives = 43/84 (51%), Gaps = 1/84 (1%)
Frame = -3
Query: 558 CVFCHHLMDEVLSKLKDPDAEFEIIQILLKECKKI-EGHEQQCKRLVLQYIPLILVNGEK 382
C C L+ + L+ + +I+ L K C + + + +QC + V +Y P+++ +
Sbjct: 410 CEVCKKLVGYLDRNLEKNSTKEQILAALEKGCSFLPDQYRKQCDQFVTEYEPVLIEILVE 469
Query: 381 FLEKNDICTIVQACDAGKKTVLGS 310
++ + +C + AC A K +LG+
Sbjct: 470 VMDPSFVCLKIGACPAAHKPLLGA 493
Score = 33.5 bits (75), Expect = 0.52
Identities = 21/82 (25%), Positives = 39/82 (47%), Gaps = 4/82 (4%)
Frame = -3
Query: 558 CVFCHHLMDEVLSKLKDPDAEFEIIQILLKECKKIE--GHEQQCKRLVLQYIPLIL--VN 391
C C ++ + LKD E EI+ L + C + CK +V Y+P+IL +
Sbjct: 63 CDICKDVITAAGNLLKDNATEQEILMYLERTCDWLPKPNMSASCKEIVDSYLPVILDMIK 122
Query: 390 GEKFLEKNDICTIVQACDAGKK 325
G+ ++C+ + C++ +K
Sbjct: 123 GQ-MSHPGEVCSALNLCESLQK 143
>SAP_MOUSE (Q61207) Sulfated glycoprotein 1 precursor (SGP-1) (Prosaposin)|
Length = 557
Score = 36.6 bits (83), Expect = 0.061
Identities = 21/84 (25%), Positives = 42/84 (50%), Gaps = 1/84 (1%)
Frame = -3
Query: 558 CVFCHHLMDEVLSKLKDPDAEFEIIQILLKECKKI-EGHEQQCKRLVLQYIPLILVNGEK 382
C C L+ + L+ + EI+ L K C + + +++QC V +Y PL+L +
Sbjct: 442 CEVCKKLVLYLEHNLEKNSTKEEILAALEKGCSFLPDPYQKQCDDFVAEYEPLLLEILVE 501
Query: 381 FLEKNDICTIVQACDAGKKTVLGS 310
++ +C+ + C + K +LG+
Sbjct: 502 VMDPGFVCSKIGVCPSAYKLLLGT 525
Score = 36.6 bits (83), Expect = 0.061
Identities = 23/79 (29%), Positives = 38/79 (48%), Gaps = 4/79 (5%)
Frame = -3
Query: 558 CVFCHHLMDEVLSKLKDPDAEFEIIQILLKECKKIEGH--EQQCKRLVLQYIPLIL--VN 391
C C ++ E + LKD + EI+ L K C+ I CK +V Y+P+IL +
Sbjct: 63 CDICKTVVTEAGNLLKDNATQEEILHYLEKTCEWIHDSSLSASCKEVVDSYLPVILDMIK 122
Query: 390 GEKFLEKNDICTIVQACDA 334
GE ++C+ + C +
Sbjct: 123 GE-MSNPGEVCSALNLCQS 140
>DSG3_MOUSE (O35902) Desmoglein-3 precursor (130 kDa pemphigus vulgaris antigen|
homolog)
Length = 993
Score = 29.3 bits (64), Expect = 9.8
Identities = 11/34 (32%), Positives = 20/34 (58%)
Frame = -3
Query: 456 IEGHEQQCKRLVLQYIPLILVNGEKFLEKNDICT 355
IEG + + K + +P + NG F+E +++CT
Sbjct: 671 IEGAQPEDKEITNICVPPVTTNGADFMESSEVCT 704
Database: uniprot_sprot.fasta
Posted date: May 25, 2006 5:36 PM
Number of letters in database: 80,573,946
Number of sequences in database: 219,361
Lambda K H
0.318 0.135 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 87,570,431
Number of Sequences: 219361
Number of extensions: 1761568
Number of successful extensions: 4992
Number of sequences better than 10.0: 15
Number of HSP's better than 10.0 without gapping: 4831
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4989
length of database: 80,573,946
effective HSP length: 107
effective length of database: 57,102,319
effective search space used: 5653129581
frameshift window, decay const: 50, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)